## Sat Jan  4 07:05:33 2025
## emapper-2.1.12
## /data/home/zhuyingjie/miniforge3/envs/eggnog/bin/emapper.py -i /data/home/zhuyingjie/01_Project/01_metagenome/mangrove/mmseqs_cluster/PRJNA629394/SRR11734709/SRR11734709_p_cluster_rep_seq.fasta --output PRJNA629394_SRR11734709 --data_dir /data/software/eggnog_database -m diamond --sensmode fast --output_dir /data/home/zhuyingjie/01_Project/01_metagenome/mangrove/annotation --temp_dir /data/software/eggnog_database/temp --excel --dbmem --cpu 24
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
k59_237494_1	933262.AXAM01000029_gene2756	4.76e-06	47.4	COG1354@1|root,COG1354@2|Bacteria,1MVCN@1224|Proteobacteria,42RG5@68525|delta/epsilon subdivisions,2WNRE@28221|Deltaproteobacteria,2MKHT@213118|Desulfobacterales	28221|Deltaproteobacteria	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves	scpA	-	-	ko:K05896	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpA
k59_237494_2	933262.AXAM01000029_gene2755	1.84e-68	217.0	COG0180@1|root,COG0180@2|Bacteria,1MV4T@1224|Proteobacteria,42MCV@68525|delta/epsilon subdivisions,2WJI2@28221|Deltaproteobacteria,2MJCB@213118|Desulfobacterales	28221|Deltaproteobacteria	J	TIGRFAM tryptophanyl-tRNA synthetase	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
k59_78346_1	1278073.MYSTI_06351	3.31e-33	128.0	COG3267@1|root,COG3267@2|Bacteria,1MU3G@1224|Proteobacteria,42MM0@68525|delta/epsilon subdivisions,2WKXZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	U	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22
k59_78346_2	237368.SCABRO_01325	0.000153	44.7	COG2206@1|root,COG2206@2|Bacteria,2J0TK@203682|Planctomycetes	203682|Planctomycetes	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	HD_5
k59_70528_1	1121013.P873_11325	0.000686	44.3	COG4796@1|root,COG4796@2|Bacteria,1QTT6@1224|Proteobacteria,1RN3Z@1236|Gammaproteobacteria,1X3SF@135614|Xanthomonadales	135614|Xanthomonadales	U	Type II secretory pathway, component HofQ	pilQ	-	-	ko:K02666	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	AMIN,STN,Secretin,Secretin_N
k59_70528_2	272123.Anacy_4175	7.5e-11	67.8	COG0642@1|root,COG0745@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria,1G0YJ@1117|Cyanobacteria,1HJHN@1161|Nostocales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
k59_161739_1	335543.Sfum_3083	9.41e-86	266.0	COG0138@1|root,COG0138@2|Bacteria,1MUDQ@1224|Proteobacteria,42MV4@68525|delta/epsilon subdivisions,2WKHZ@28221|Deltaproteobacteria,2MQ6K@213462|Syntrophobacterales	28221|Deltaproteobacteria	F	PFAM AICARFT IMPCHase bienzyme	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
k59_123874_1	177439.DP0903	8.33e-47	164.0	COG0518@1|root,COG0519@1|root,COG0518@2|Bacteria,COG0519@2|Bacteria,1MU2A@1224|Proteobacteria,42M0I@68525|delta/epsilon subdivisions,2WJ6D@28221|Deltaproteobacteria,2MJ7G@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Catalyzes the synthesis of GMP from XMP	guaA	GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase,tRNA_Me_trans
k59_123874_2	1125725.HMPREF1325_0312	5.2e-16	77.8	COG0587@1|root,COG0587@2|Bacteria,2J5B5@203691|Spirochaetes	203691|Spirochaetes	L	DNA-directed DNA polymerase	dnaE	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
k59_101006_1	1167006.UWK_01346	5.84e-86	269.0	COG1249@1|root,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,42MBP@68525|delta/epsilon subdivisions,2WJAJ@28221|Deltaproteobacteria,2MHTN@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Pyr_redox_dim
k59_10103_1	1366050.N234_28120	1.79e-81	270.0	COG0515@1|root,COG2203@1|root,COG3899@1|root,COG4191@1|root,COG0515@2|Bacteria,COG2203@2|Bacteria,COG3899@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2VICN@28216|Betaproteobacteria,1K3Q3@119060|Burkholderiaceae	28216|Betaproteobacteria	T	ATP-binding region ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GAF,HATPase_c,HisKA,PAS_3,PAS_9,Pkinase
k59_32677_1	1547437.LL06_15435	5.58e-13	70.1	COG0559@1|root,COG0559@2|Bacteria,1N5XH@1224|Proteobacteria,2TSH5@28211|Alphaproteobacteria,43KGM@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	E	Branched-chain amino acid transport system / permease component	MA20_16475	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
k59_161759_1	1232437.KL662031_gene2526	1.44e-78	255.0	COG1148@1|root,COG1148@2|Bacteria,1QUM4@1224|Proteobacteria,42MPP@68525|delta/epsilon subdivisions,2WJ3U@28221|Deltaproteobacteria,2MMQ1@213118|Desulfobacterales	28221|Deltaproteobacteria	C	NAD(P)-binding Rossmann-like domain	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_6,Pyr_redox_2
k59_168999_1	1125863.JAFN01000001_gene1218	3.56e-64	217.0	COG1529@1|root,COG1529@2|Bacteria,1MUEA@1224|Proteobacteria,42MER@68525|delta/epsilon subdivisions,2WIYV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	aldehyde oxidase and xanthine dehydrogenase, a b hammerhead	-	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
k59_101014_1	1089553.Tph_c14870	9.45e-48	162.0	COG3383@1|root,COG3383@2|Bacteria,1V1Y2@1239|Firmicutes,24FSX@186801|Clostridia,42I7W@68295|Thermoanaerobacterales	186801|Clostridia	C	NADH-ubiquinone oxidoreductase-G iron-sulfur binding region	-	-	1.17.1.9,1.6.5.3	ko:K00123,ko:K00336	ko00190,ko00630,ko00680,ko01100,ko01120,ko01200,map00190,map00630,map00680,map01100,map01120,map01200	M00144	R00519,R11945	RC00061,RC02796	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,Fer4,Fer4_21,NADH-G_4Fe-4S_3
k59_108446_1	933262.AXAM01000005_gene2494	9.01e-66	212.0	COG1706@1|root,COG1706@2|Bacteria,1MVKW@1224|Proteobacteria,42MAU@68525|delta/epsilon subdivisions,2WK22@28221|Deltaproteobacteria,2MI2Y@213118|Desulfobacterales	28221|Deltaproteobacteria	N	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation	flgI	-	-	ko:K02394	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FlgI
k59_161770_1	670292.JH26_20290	3.16e-66	209.0	COG3665@1|root,COG3665@2|Bacteria,1N9DM@1224|Proteobacteria,2TSFM@28211|Alphaproteobacteria,1JUEV@119045|Methylobacteriaceae	28211|Alphaproteobacteria	S	Domain of unknown function (DUF1989)	-	-	-	ko:K09967	-	-	-	-	ko00000	-	-	-	DUF1989
k59_85708_1	555779.Dthio_PD0367	1.35e-22	96.3	COG2199@1|root,COG2208@1|root,COG2208@2|Bacteria,COG3706@2|Bacteria,1N4K5@1224|Proteobacteria,42T2F@68525|delta/epsilon subdivisions,2WPGM@28221|Deltaproteobacteria,2MGHA@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	response regulator, receiver	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	Response_reg,SpoIIE
k59_207205_1	1038869.AXAN01000020_gene4136	6.36e-34	131.0	COG1488@1|root,COG1488@2|Bacteria,1MV8U@1224|Proteobacteria,2VGZ5@28216|Betaproteobacteria,1K2JW@119060|Burkholderiaceae	28216|Betaproteobacteria	F	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP	pncB	GO:0000183,GO:0001302,GO:0003674,GO:0003824,GO:0004516,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0006139,GO:0006325,GO:0006342,GO:0006348,GO:0006355,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006996,GO:0007568,GO:0007569,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016043,GO:0016458,GO:0016874,GO:0016879,GO:0018130,GO:0019219,GO:0019222,GO:0019357,GO:0019358,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032502,GO:0034641,GO:0034654,GO:0040029,GO:0043094,GO:0043173,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0045814,GO:0045892,GO:0045934,GO:0046483,GO:0046497,GO:0048519,GO:0048523,GO:0048869,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051186,GO:0051188,GO:0051252,GO:0051253,GO:0051276,GO:0055086,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0072524,GO:0072525,GO:0080090,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141	6.3.4.21	ko:K00763	ko00760,ko01100,map00760,map01100	-	R01724	RC00033	ko00000,ko00001,ko01000	-	-	-	NAPRTase
k59_237524_1	1121405.dsmv_2203	1.17e-84	259.0	COG0329@1|root,COG0329@2|Bacteria,1MUCM@1224|Proteobacteria,42M0X@68525|delta/epsilon subdivisions,2WK4D@28221|Deltaproteobacteria,2MHXX@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
k59_222390_1	933262.AXAM01000016_gene178	2.52e-102	307.0	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,42MSR@68525|delta/epsilon subdivisions,2WIXG@28221|Deltaproteobacteria,2MI9F@213118|Desulfobacterales	28221|Deltaproteobacteria	I	Belongs to the thiolase family	bamN	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
k59_17357_1	706587.Desti_3169	8.17e-48	166.0	COG0683@1|root,COG0683@2|Bacteria,1MXPJ@1224|Proteobacteria,42NFF@68525|delta/epsilon subdivisions,2WKDK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Amino acid amide ABC transporter substrate-binding protein, HAAT family	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
k59_25133_2	875454.BAEW01000002_gene398	8.1e-09	59.3	COG0125@1|root,COG0125@2|Bacteria,1V1HE@1239|Firmicutes,24HHC@186801|Clostridia,22HCP@1570339|Peptoniphilaceae	186801|Clostridia	F	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	tmk	-	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylate_kin
k59_131387_1	1408428.JNJP01000076_gene2780	5.21e-26	102.0	COG1148@1|root,COG1148@2|Bacteria,1QV9V@1224|Proteobacteria,42SKG@68525|delta/epsilon subdivisions,2WP8G@28221|Deltaproteobacteria,2MBB5@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	PFAM NIL domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_4,Fer4_7,NIL
k59_115907_1	292563.Cyast_2883	0.000516	41.6	COG0174@1|root,COG0174@2|Bacteria,1G255@1117|Cyanobacteria	1117|Cyanobacteria	E	glutamine synthetase	glnA	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
k59_115907_2	933262.AXAM01000040_gene1228	4.2e-55	174.0	COG0347@1|root,COG0347@2|Bacteria,1RGWK@1224|Proteobacteria,42SJJ@68525|delta/epsilon subdivisions,2WP4E@28221|Deltaproteobacteria,2MK8A@213118|Desulfobacterales	28221|Deltaproteobacteria	K	Belongs to the P(II) protein family	-	-	-	ko:K04751	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	P-II
k59_17372_1	335543.Sfum_3291	2.51e-32	128.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,42MK5@68525|delta/epsilon subdivisions,2WJ3Z@28221|Deltaproteobacteria,2MQ86@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	PFAM Acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
k59_55649_1	572546.Arcpr_1846	2.79e-33	128.0	COG4177@1|root,arCOG01274@2157|Archaea,2XW08@28890|Euryarchaeota,2463K@183980|Archaeoglobi	183980|Archaeoglobi	E	Branched-chain amino acid transport system / permease component	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
k59_108465_1	439235.Dalk_1818	4.53e-36	131.0	COG0437@1|root,COG0437@2|Bacteria,1MU1B@1224|Proteobacteria,42M97@68525|delta/epsilon subdivisions,2WJB4@28221|Deltaproteobacteria,2MJB7@213118|Desulfobacterales	28221|Deltaproteobacteria	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	DmsC,Fer4_11,Fer4_4
k59_108465_2	439235.Dalk_1819	2.15e-44	155.0	COG5557@1|root,COG5557@2|Bacteria,1MWYI@1224|Proteobacteria,42PH3@68525|delta/epsilon subdivisions,2WJZH@28221|Deltaproteobacteria,2MIN0@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Polysulphide reductase, NrfD	-	-	-	-	-	-	-	-	-	-	-	-	NrfD
k59_237550_1	1156919.QWC_09974	3.71e-13	77.4	COG0726@1|root,COG2304@1|root,COG2931@1|root,COG0726@2|Bacteria,COG2304@2|Bacteria,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,2VKA9@28216|Betaproteobacteria,3T4YM@506|Alcaligenaceae	28216|Betaproteobacteria	Q	von Willebrand factor (vWF) type A domain	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,He_PIG,HemolysinCabind,VWA_2
k59_32707_1	933262.AXAM01000023_gene662	7.51e-78	252.0	COG0539@1|root,COG0539@2|Bacteria,1MVAV@1224|Proteobacteria,42M29@68525|delta/epsilon subdivisions,2WJ0X@28221|Deltaproteobacteria,2MI6Q@213118|Desulfobacterales	28221|Deltaproteobacteria	J	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence	rpsA	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
k59_222409_1	258052.JNYV01000002_gene1601	9.47e-09	58.9	COG2050@1|root,COG2050@2|Bacteria,2GKY1@201174|Actinobacteria	201174|Actinobacteria	Q	PFAM thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
k59_70545_1	502025.Hoch_3072	1.66e-63	212.0	COG1070@1|root,COG1070@2|Bacteria,1MW4A@1224|Proteobacteria,42Q1B@68525|delta/epsilon subdivisions,2WKJH@28221|Deltaproteobacteria,2YU85@29|Myxococcales	28221|Deltaproteobacteria	G	FGGY family of carbohydrate kinases, N-terminal domain	-	-	2.7.1.17	ko:K00854	ko00040,ko01100,map00040,map01100	M00014	R01639	RC00002,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	-	FGGY_C,FGGY_N
k59_222410_2	498761.HM1_2618	1.48e-29	117.0	COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia	186801|Clostridia	C	electron transfer flavoprotein	-	-	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
k59_2261_1	1232437.KL661961_gene2983	5.45e-60	195.0	COG2358@1|root,COG2358@2|Bacteria,1MXW1@1224|Proteobacteria,42MGJ@68525|delta/epsilon subdivisions,2WJ5E@28221|Deltaproteobacteria,2MHXN@213118|Desulfobacterales	28221|Deltaproteobacteria	S	TIGRFAM TRAP transporter solute receptor, TAXI family	-	-	-	ko:K07080	-	-	-	-	ko00000	-	-	-	NMT1_3
k59_169044_1	879212.DespoDRAFT_02969	2.97e-43	154.0	COG0438@1|root,COG0438@2|Bacteria,1NA28@1224|Proteobacteria,42NZA@68525|delta/epsilon subdivisions,2WK1T@28221|Deltaproteobacteria,2MIH3@213118|Desulfobacterales	28221|Deltaproteobacteria	M	PFAM Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	DUF3524,Glycos_transf_1
k59_146416_2	448385.sce1496	4.4e-26	107.0	COG0025@1|root,COG0025@2|Bacteria,1MW5T@1224|Proteobacteria,42M9Y@68525|delta/epsilon subdivisions,2WTUE@28221|Deltaproteobacteria,2YV6R@29|Myxococcales	28221|Deltaproteobacteria	P	Sodium/hydrogen exchanger family	-	-	-	ko:K03316	-	-	-	-	ko00000	2.A.36	-	-	Na_H_Exchanger
k59_161780_1	56780.SYN_02917	2.66e-94	288.0	COG2509@1|root,COG2509@2|Bacteria,1MV6P@1224|Proteobacteria,42N2K@68525|delta/epsilon subdivisions,2WJ5D@28221|Deltaproteobacteria,2MR6D@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	FAD binding domain	-	-	-	ko:K07137	-	-	-	-	ko00000	-	-	-	DAO,FAD_binding_2,GIDA,HI0933_like,Pyr_redox_2
k59_78382_1	656519.Halsa_0481	1.02e-66	224.0	COG0556@1|root,COG0556@2|Bacteria,1TPKB@1239|Firmicutes,247P7@186801|Clostridia,3WACS@53433|Halanaerobiales	186801|Clostridia	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
k59_78382_2	1121405.dsmv_2803	5.78e-46	164.0	COG0322@1|root,COG0322@2|Bacteria,1MV38@1224|Proteobacteria,42MB1@68525|delta/epsilon subdivisions,2WJ76@28221|Deltaproteobacteria,2MIHC@213118|Desulfobacterales	28221|Deltaproteobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:1902494,GO:1905347,GO:1905348,GO:1990391	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N
k59_85745_1	335543.Sfum_2062	3.9e-69	223.0	COG0057@1|root,COG0057@2|Bacteria,1R8ZT@1224|Proteobacteria,42PY6@68525|delta/epsilon subdivisions,2WKEI@28221|Deltaproteobacteria,2MR58@213462|Syntrophobacterales	28221|Deltaproteobacteria	G	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain	-	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
k59_154316_1	933262.AXAM01000017_gene3137	4.2e-102	327.0	COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1143@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1143@2|Bacteria,1MVM0@1224|Proteobacteria,42MZ0@68525|delta/epsilon subdivisions,2WJ96@28221|Deltaproteobacteria,2MHRJ@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	poR	-	1.2.7.1	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00173,M00307	R01196,R10866	RC00004,RC02742	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	EKR,Fer4_16,PFOR_II,POR,POR_N,TPP_enzyme_C
k59_161786_1	1121405.dsmv_0697	6.14e-31	116.0	COG1410@1|root,COG1410@2|Bacteria,1RGFK@1224|Proteobacteria,42RMB@68525|delta/epsilon subdivisions,2WNS1@28221|Deltaproteobacteria,2MJX5@213118|Desulfobacterales	28221|Deltaproteobacteria	E	PFAM dihydropteroate synthase DHPS	-	-	2.1.1.258	ko:K15023	ko00720,ko01120,ko01200,map00720,map01120,map01200	M00377	R02289,R10243	RC00004,RC00113,RC01144,RC02871,RC02977	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
k59_108490_1	631362.Thi970DRAFT_04432	4.52e-100	304.0	COG3263@1|root,COG3263@2|Bacteria,1MVKV@1224|Proteobacteria,1T2D1@1236|Gammaproteobacteria,1X28U@135613|Chromatiales	135613|Chromatiales	P	Sodium/hydrogen exchanger family	-	-	-	ko:K11105	-	-	-	-	ko00000,ko02000	2.A.36.6	-	-	Na_H_Exchanger
k59_10147_1	706587.Desti_2679	1.67e-85	264.0	COG1168@1|root,COG1168@2|Bacteria,1MY33@1224|Proteobacteria,42M6F@68525|delta/epsilon subdivisions,2WK37@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	PFAM aminotransferase class I and II	-	-	4.4.1.8	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	-	R00782,R01286,R02408,R04941	RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
k59_154317_1	335543.Sfum_1300	2.02e-26	105.0	2EFDI@1|root,3396C@2|Bacteria,1N9D7@1224|Proteobacteria,42W2W@68525|delta/epsilon subdivisions,2WR8J@28221|Deltaproteobacteria,2MS20@213462|Syntrophobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_184470_1	96561.Dole_1148	6.79e-94	289.0	COG4269@1|root,COG4269@2|Bacteria,1MW5P@1224|Proteobacteria,42R97@68525|delta/epsilon subdivisions,2WMRA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Bacterial protein of unknown function (DUF898)	-	-	-	-	-	-	-	-	-	-	-	-	DUF898
k59_10156_2	335543.Sfum_3207	6.9e-30	115.0	COG0115@1|root,COG0115@2|Bacteria,1MVB0@1224|Proteobacteria,42PRS@68525|delta/epsilon subdivisions,2WK0H@28221|Deltaproteobacteria	28221|Deltaproteobacteria	EH	PFAM aminotransferase, class IV	-	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
k59_2284_1	402777.KB235903_gene401	6.5e-63	217.0	COG0457@1|root,COG3914@1|root,COG0457@2|Bacteria,COG3914@2|Bacteria,1G0YS@1117|Cyanobacteria,1H82I@1150|Oscillatoriales	1117|Cyanobacteria	O	O-linked N-acetylglucosamine transferase SPINDLY family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_41,Glycos_transf_2,Sulfotransfer_2,TPR_1,TPR_11,TPR_16,TPR_17,TPR_19,TPR_2,TPR_8
k59_229923_1	1121918.ARWE01000001_gene1693	3.27e-56	183.0	COG1296@1|root,COG1296@2|Bacteria,1P6U3@1224|Proteobacteria,42QVQ@68525|delta/epsilon subdivisions,2WMW1@28221|Deltaproteobacteria,43T17@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	AzlC protein	-	-	-	-	-	-	-	-	-	-	-	-	AzlC
k59_229923_2	335543.Sfum_0195	3.78e-24	94.0	COG4392@1|root,COG4392@2|Bacteria,1NEQP@1224|Proteobacteria,42VHX@68525|delta/epsilon subdivisions,2WRER@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Branched-chain amino acid transport protein (AzlD)	-	-	-	-	-	-	-	-	-	-	-	-	AzlD
k59_214576_1	335543.Sfum_3089	4.5e-162	466.0	COG1060@1|root,COG1060@2|Bacteria,1QN23@1224|Proteobacteria,42M6Z@68525|delta/epsilon subdivisions,2WJ4C@28221|Deltaproteobacteria,2MQ6F@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate	mqnE	-	1.21.98.1,2.5.1.120,2.5.1.77	ko:K11779,ko:K11784,ko:K18285	ko00130,ko00680,ko01110,ko01120,map00130,map00680,map01110,map01120	M00378	R08588,R09396,R10667	RC00021,RC01381,RC02329,RC03002,RC03007,RC03234	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_3391	Radical_SAM
k59_47939_1	530564.Psta_1836	1.18e-76	248.0	COG3519@1|root,COG3519@2|Bacteria,2IYES@203682|Planctomycetes	203682|Planctomycetes	S	TIGRFAM type VI secretion protein, VC_A0110 family	-	-	-	ko:K11896	-	M00334	-	-	ko00000,ko00002,ko02044	3.A.23.1	-	-	T6SS_TssF
k59_131425_1	926569.ANT_15550	2.21e-76	243.0	COG1032@1|root,COG1032@2|Bacteria,2G6X0@200795|Chloroflexi	200795|Chloroflexi	C	B12 binding domain	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,DUF4070,Radical_SAM
k59_154339_1	237368.SCABRO_01744	5.32e-36	134.0	COG3666@1|root,COG3666@2|Bacteria,2J1Y1@203682|Planctomycetes	203682|Planctomycetes	L	Transposase domain (DUF772)	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_6,DUF772
k59_71076_1	933262.AXAM01000010_gene1381	3.56e-100	312.0	COG0768@1|root,COG0768@2|Bacteria,1MV8C@1224|Proteobacteria,42M1S@68525|delta/epsilon subdivisions,2WJ02@28221|Deltaproteobacteria,2MHV4@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Penicillin-binding Protein dimerisation domain	mrdA	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	iAF987.Gmet_0928	PBP_dimer,Transpeptidase
k59_192446_1	643648.Slip_0189	1.25e-44	154.0	COG0123@1|root,COG0123@2|Bacteria,1V066@1239|Firmicutes,2483W@186801|Clostridia,42KJV@68298|Syntrophomonadaceae	186801|Clostridia	BQ	Histone deacetylase domain	-	-	-	-	-	-	-	-	-	-	-	-	Hist_deacetyl
k59_40878_1	1151292.QEW_1684	0.000262	49.7	COG3103@1|root,COG4193@1|root,COG3103@2|Bacteria,COG4193@2|Bacteria,COG4991@2|Bacteria,1V0NC@1239|Firmicutes,25BAR@186801|Clostridia,25UK8@186804|Peptostreptococcaceae	186801|Clostridia	GT	Src homology 3 domains	-	-	-	-	-	-	-	-	-	-	-	-	Glucosaminidase,SH3_3
k59_139573_1	1121423.JONT01000035_gene904	2.22e-28	121.0	COG1196@1|root,COG5283@1|root,COG1196@2|Bacteria,COG5283@2|Bacteria,1UHQM@1239|Firmicutes,25E9Q@186801|Clostridia	186801|Clostridia	M	phage tail tape measure protein	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23,PhageMin_Tail
k59_71085_1	1408254.T458_04770	1.07e-85	266.0	COG0001@1|root,COG0001@2|Bacteria,1TPNH@1239|Firmicutes,4HANQ@91061|Bacilli,26QYR@186822|Paenibacillaceae	91061|Bacilli	H	Glutamate-1-semialdehyde aminotransferase	hemL	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	iSB619.SA_RS08395	Aminotran_3
k59_33285_1	941449.dsx2_1873	2.97e-145	456.0	COG0577@1|root,COG2234@1|root,COG0577@2|Bacteria,COG2234@2|Bacteria,1MVYE@1224|Proteobacteria,42PKN@68525|delta/epsilon subdivisions,2WIWP@28221|Deltaproteobacteria,2M8ZJ@213115|Desulfovibrionales	28221|Deltaproteobacteria	V	FtsX-like permease family	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,PA,Peptidase_M28
k59_2768_1	1487921.DP68_13375	2.84e-48	170.0	COG0642@1|root,COG3437@1|root,COG2205@2|Bacteria,COG3437@2|Bacteria,1TQMV@1239|Firmicutes,247SE@186801|Clostridia,36ERF@31979|Clostridiaceae	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
k59_56237_1	240016.ABIZ01000001_gene769	4.11e-20	93.6	COG4591@1|root,COG4591@2|Bacteria,46Z4Y@74201|Verrucomicrobia,2IVII@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	FtsX-like permease family	-	-	-	-	-	-	-	-	-	-	-	-	FtsX
k59_56237_2	1121405.dsmv_2053	1.01e-45	157.0	COG0727@1|root,COG0727@2|Bacteria,1RDHS@1224|Proteobacteria,42RM7@68525|delta/epsilon subdivisions,2WNHD@28221|Deltaproteobacteria,2MJV8@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Putative zinc- or iron-chelating domain	-	-	-	-	-	-	-	-	-	-	-	-	CxxCxxCC
k59_139581_1	177439.DP0096	5.29e-81	248.0	COG0428@1|root,COG0428@2|Bacteria,1MWEZ@1224|Proteobacteria,42NT2@68525|delta/epsilon subdivisions,2WJM5@28221|Deltaproteobacteria,2MJ6D@213118|Desulfobacterales	28221|Deltaproteobacteria	P	ZIP Zinc transporter	gufA	-	-	ko:K07238	-	-	-	-	ko00000,ko02000	2.A.5.5	-	-	Zip
k59_139581_2	1125863.JAFN01000001_gene1563	4.24e-19	84.3	COG1305@1|root,COG1305@2|Bacteria,1R9XR@1224|Proteobacteria,42QTZ@68525|delta/epsilon subdivisions,2WMV1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	PFAM transglutaminase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
k59_71094_1	1304885.AUEY01000002_gene424	4.86e-70	233.0	COG0643@1|root,COG0643@2|Bacteria,1MUAG@1224|Proteobacteria,42M6Q@68525|delta/epsilon subdivisions,2WJ5U@28221|Deltaproteobacteria,2MHZP@213118|Desulfobacterales	28221|Deltaproteobacteria	NT	Signal transducing histidine kinase, homodimeric	-	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt
k59_185334_1	338963.Pcar_0534	1.1e-34	136.0	COG3666@1|root,COG3666@2|Bacteria,1N3QR@1224|Proteobacteria,42N7X@68525|delta/epsilon subdivisions,2WMM9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_6,DUF772
k59_192465_1	315730.BcerKBAB4_5752	4.74e-25	102.0	2CIJK@1|root,33ZV7@2|Bacteria,1VXUZ@1239|Firmicutes,4HXMR@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_108974_1	439235.Dalk_2445	2.42e-110	327.0	COG2046@1|root,COG2046@2|Bacteria,1MUQB@1224|Proteobacteria,42NAI@68525|delta/epsilon subdivisions,2WJYY@28221|Deltaproteobacteria,2MIP2@213118|Desulfobacterales	28221|Deltaproteobacteria	P	sulfate adenylyltransferase	sat	-	2.7.1.25,2.7.7.4	ko:K00958,ko:K13811	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00509,R00529,R04928,R04929	RC00002,RC00078,RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase,ATP-sulfurylase,PUA_2
k59_78967_1	386456.JQKN01000001_gene1666	1.71e-13	75.5	COG0784@1|root,COG3920@1|root,arCOG02348@1|root,arCOG02352@1|root,arCOG02335@2157|Archaea,arCOG02348@2157|Archaea,arCOG02352@2157|Archaea,arCOG06537@2157|Archaea	2157|Archaea	T	response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA_2,PAS,PAS_3,PAS_4,PAS_9,Response_reg
k59_223047_1	1318628.MARLIPOL_05415	1.66e-105	335.0	COG0591@1|root,COG0642@1|root,COG0591@2|Bacteria,COG2205@2|Bacteria,1MUY7@1224|Proteobacteria,1RP2U@1236|Gammaproteobacteria,46A0J@72275|Alteromonadaceae	1236|Gammaproteobacteria	ET	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_7,Response_reg
k59_185338_1	555088.DealDRAFT_0130	1.74e-16	82.8	COG1600@1|root,COG1600@2|Bacteria,1UFJF@1239|Firmicutes,24GR0@186801|Clostridia	186801|Clostridia	C	binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_56245_1	96561.Dole_0545	4.28e-16	77.0	COG0330@1|root,COG0330@2|Bacteria,1MUM2@1224|Proteobacteria,42NUT@68525|delta/epsilon subdivisions,2WKQX@28221|Deltaproteobacteria,2MI5I@213118|Desulfobacterales	28221|Deltaproteobacteria	O	HflC and HflK could encode or regulate a protease	hflK	-	-	ko:K04088	-	M00742	-	-	ko00000,ko00002,ko01000	-	-	-	Band_7
k59_56245_2	933262.AXAM01000031_gene3021	1.09e-118	350.0	COG0330@1|root,COG0330@2|Bacteria,1MV7R@1224|Proteobacteria,42N2V@68525|delta/epsilon subdivisions,2WIPS@28221|Deltaproteobacteria,2MIPC@213118|Desulfobacterales	28221|Deltaproteobacteria	O	HflC and HflK could regulate a protease	hflC	-	-	ko:K04087	-	M00742	-	-	ko00000,ko00002,ko01000	-	-	-	Band_7
k59_206308_1	706587.Desti_3164	1.02e-81	258.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,42M5F@68525|delta/epsilon subdivisions,2WISF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	IQ	PFAM AMP-dependent synthetase and ligase	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
k59_77473_1	381666.PHG041	2.84e-07	55.8	COG0582@1|root,COG0582@2|Bacteria,1NX90@1224|Proteobacteria,2VJRU@28216|Betaproteobacteria,1K5P0@119060|Burkholderiaceae	28216|Betaproteobacteria	L	integrase recombinase Y4RB (NP_444040))	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
k59_9092_1	1089439.KB902270_gene2593	1.54e-47	165.0	COG5323@1|root,COG5323@2|Bacteria,1MW8S@1224|Proteobacteria,1SYQD@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Terminase RNaseH-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Terminase_6C
k59_9092_2	697281.Mahau_0566	1.52e-24	100.0	COG3728@1|root,COG3728@2|Bacteria,1VAD9@1239|Firmicutes,24JSU@186801|Clostridia	186801|Clostridia	L	Terminase Small Subunit	-	-	-	ko:K07474	-	-	-	-	ko00000	-	-	-	Terminase_2
k59_1435_1	1125863.JAFN01000001_gene688	6.01e-54	190.0	COG1298@1|root,COG1298@2|Bacteria,1MUF3@1224|Proteobacteria,42NB2@68525|delta/epsilon subdivisions,2WIWG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	N	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin	flhA	-	-	ko:K02400	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	FHIPEP
k59_175911_1	163908.KB235896_gene4764	2.43e-47	157.0	COG3335@1|root,COG3335@2|Bacteria,1G9JW@1117|Cyanobacteria	1117|Cyanobacteria	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISAZ013
k59_175911_2	1173020.Cha6605_6235	1.13e-93	284.0	COG3335@1|root,COG3335@2|Bacteria,1G3S8@1117|Cyanobacteria	1117|Cyanobacteria	L	Rhodopirellula transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISAZ013
k59_31810_2	247490.KSU1_C1051	2.59e-10	68.9	COG3419@1|root,COG3419@2|Bacteria	2|Bacteria	NU	Tfp pilus assembly protein tip-associated adhesin	pilY1	-	-	ko:K02674	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	CarboxypepD_reg,Neisseria_PilC
k59_31810_4	644968.DFW101_3505	1.71e-10	63.5	2BTNS@1|root,32NVS@2|Bacteria,1RJWC@1224|Proteobacteria,4339K@68525|delta/epsilon subdivisions,2WXRT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_62307_1	96561.Dole_1467	3.43e-93	283.0	COG1090@1|root,COG1090@2|Bacteria,1MUB4@1224|Proteobacteria,42QUU@68525|delta/epsilon subdivisions,2WKRY@28221|Deltaproteobacteria,2MJ1I@213118|Desulfobacterales	28221|Deltaproteobacteria	S	epimerase dehydratase	-	-	-	ko:K07071	-	-	-	-	ko00000	-	-	-	DUF1731,Epimerase
k59_62309_1	335543.Sfum_3079	1.39e-67	217.0	COG0620@1|root,COG0620@2|Bacteria,1R6KI@1224|Proteobacteria,42PCN@68525|delta/epsilon subdivisions,2WKT3@28221|Deltaproteobacteria,2MRM1@213462|Syntrophobacterales	28221|Deltaproteobacteria	E	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_39457_1	909663.KI867150_gene410	5.36e-96	304.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MFW@68525|delta/epsilon subdivisions,2WKMP@28221|Deltaproteobacteria,2MQVW@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_9,Response_reg
k59_9106_1	1121403.AUCV01000079_gene4212	5.46e-106	311.0	COG0160@1|root,COG0160@2|Bacteria,1R5BV@1224|Proteobacteria,42PBI@68525|delta/epsilon subdivisions,2WM05@28221|Deltaproteobacteria,2MIJT@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Aminotransferase class-III	-	-	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
k59_92897_1	439235.Dalk_0681	1.09e-104	322.0	COG1614@1|root,COG1614@2|Bacteria,1MVI5@1224|Proteobacteria,42N9A@68525|delta/epsilon subdivisions,2WK4H@28221|Deltaproteobacteria,2MIRV@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM CO dehydrogenase acetyl-CoA synthase complex beta subunit	-	-	2.3.1.169	ko:K14138	ko00720,ko01120,ko01200,map00720,map01120,map01200	M00377	R08433,R10243	RC00004,RC00113,RC01144,RC02963,RC02964,RC02977	ko00000,ko00001,ko00002,ko01000	-	-	-	CdhC
k59_9658_1	945713.IALB_2618	1.03e-127	376.0	COG3033@1|root,COG3033@2|Bacteria	2|Bacteria	E	tryptophanase activity	tnaA	-	4.1.99.1	ko:K01667	ko00380,map00380	-	R00673	RC00209,RC00355	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
k59_191488_1	439235.Dalk_1318	1.24e-76	231.0	COG1943@1|root,COG1943@2|Bacteria,1MX19@1224|Proteobacteria,43BHF@68525|delta/epsilon subdivisions,2WQUJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	PFAM Transposase IS200 like	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
k59_123374_2	1121448.DGI_1721	1.19e-73	224.0	2ARF5@1|root,31GRB@2|Bacteria,1RJBS@1224|Proteobacteria,42SKA@68525|delta/epsilon subdivisions,2WPHN@28221|Deltaproteobacteria,2MB9R@213115|Desulfovibrionales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	AmiS_UreI
k59_214215_1	28072.Nos7524_2231	5.24e-25	108.0	2EMFU@1|root,33F4J@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_8
k59_168635_2	573413.Spirs_0155	4.72e-30	118.0	COG0455@1|root,COG0455@2|Bacteria,2J5K5@203691|Spirochaetes	203691|Spirochaetes	D	ATP-binding protein	ylxH-2	-	-	ko:K04562	-	-	-	-	ko00000,ko02035	-	-	-	CbiA,ParA
k59_229423_1	998674.ATTE01000001_gene3883	6.71e-36	131.0	COG4149@1|root,COG4149@2|Bacteria,1MUXR@1224|Proteobacteria,1RRDV@1236|Gammaproteobacteria,461SD@72273|Thiotrichales	72273|Thiotrichales	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02018	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	-	BPD_transp_1
k59_161366_1	401053.AciPR4_2332	5.59e-16	81.3	COG2374@1|root,COG4932@1|root,COG5276@1|root,COG2374@2|Bacteria,COG4932@2|Bacteria,COG5276@2|Bacteria,3Y8ZJ@57723|Acidobacteria	57723|Acidobacteria	M	Protein of unknown function (DUF3494)	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,DUF3494
k59_161366_2	685778.AORL01000004_gene3448	6.59e-05	44.3	COG1028@1|root,COG1028@2|Bacteria,1MWJI@1224|Proteobacteria,2TRNJ@28211|Alphaproteobacteria,2K382@204457|Sphingomonadales	204457|Sphingomonadales	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
k59_85301_1	335543.Sfum_3202	3.9e-77	242.0	COG0181@1|root,COG0181@2|Bacteria,1MU56@1224|Proteobacteria,42M84@68525|delta/epsilon subdivisions,2WJ5V@28221|Deltaproteobacteria,2MQX5@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps	hemC	GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.61	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084	RC02317	ko00000,ko00001,ko00002,ko01000	-	-	-	Porphobil_deam,Porphobil_deamC
k59_108098_1	555779.Dthio_PD1145	4.19e-51	170.0	COG0207@1|root,COG0207@2|Bacteria,1Q4ZG@1224|Proteobacteria,42QWZ@68525|delta/epsilon subdivisions,2WMY5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	Thymidylate synthase	-	-	2.1.1.45	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	M00053	R02101	RC00219,RC00332	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylat_synt
k59_32285_1	29730.Gorai.009G191500.1	3.72e-11	68.6	COG0564@1|root,KOG0032@1|root,KOG0032@2759|Eukaryota,KOG1919@2759|Eukaryota,37K7F@33090|Viridiplantae,3GD8W@35493|Streptophyta	35493|Streptophyta	T	calcium-dependent protein kinase	-	GO:0001101,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0004683,GO:0005488,GO:0005515,GO:0005516,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006952,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009620,GO:0009719,GO:0009725,GO:0009737,GO:0009738,GO:0009755,GO:0009931,GO:0009987,GO:0010033,GO:0010857,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018105,GO:0018193,GO:0018209,GO:0019538,GO:0023052,GO:0032870,GO:0033993,GO:0035556,GO:0036211,GO:0042221,GO:0043170,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0046777,GO:0047484,GO:0048518,GO:0048583,GO:0048584,GO:0050789,GO:0050794,GO:0050832,GO:0050896,GO:0051704,GO:0051707,GO:0051716,GO:0065007,GO:0070887,GO:0071215,GO:0071229,GO:0071310,GO:0071396,GO:0071495,GO:0071704,GO:0071944,GO:0080134,GO:0097305,GO:0097306,GO:0098542,GO:0140096,GO:1901000,GO:1901002,GO:1901564,GO:1901700,GO:1901701	2.7.11.1,5.4.99.23	ko:K06180,ko:K13412	ko04626,ko05145,map04626,map05145	-	-	-	ko00000,ko00001,ko01000,ko01001,ko03009	-	-	-	EF-hand_1,EF-hand_5,EF-hand_7,Pkinase
k59_32285_2	1216932.CM240_2476	2.26e-18	84.0	COG4956@1|root,COG4956@2|Bacteria,1TP0P@1239|Firmicutes,248F4@186801|Clostridia,36DKW@31979|Clostridiaceae	186801|Clostridia	S	PFAM PilT protein domain protein	yacL	-	-	-	-	-	-	-	-	-	-	-	PIN,PIN_4,TRAM
k59_17046_1	1128421.JAGA01000002_gene1304	4.02e-19	93.2	COG4262@1|root,COG4262@2|Bacteria	2|Bacteria	H	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	-	-	-	-	-	-	-	-	-	-	-	-	Spermine_synth
k59_221969_1	335543.Sfum_3724	1.56e-92	288.0	COG0077@1|root,COG2876@1|root,COG0077@2|Bacteria,COG2876@2|Bacteria,1QVAD@1224|Proteobacteria,42MU4@68525|delta/epsilon subdivisions,2WJ8Y@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	PFAM DAHP synthetase I KDSA	-	-	2.5.1.54,5.4.99.5	ko:K03856,ko:K04516	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022,M00024,M00025	R01715,R01826	RC00435,RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,CM_2,DAHP_synth_1,PDT
k59_17054_1	589865.DaAHT2_2039	1.51e-17	81.6	COG0637@1|root,COG0637@2|Bacteria,1QW0J@1224|Proteobacteria,43BQD@68525|delta/epsilon subdivisions,2X71F@28221|Deltaproteobacteria,2MPIT@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
k59_199156_2	326426.Bbr_1779	0.000844	47.8	COG0584@1|root,COG0584@2|Bacteria,2GNM5@201174|Actinobacteria,4CYS4@85004|Bifidobacteriales	201174|Actinobacteria	C	Glycerophosphoryl diester phosphodiesterase family	glpQ	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD,Laminin_G_3
k59_85325_1	662479.C440_05258	4.1e-23	100.0	COG1184@1|root,arCOG01127@2157|Archaea,2XUMH@28890|Euryarchaeota,23SF4@183963|Halobacteria	183963|Halobacteria	J	Belongs to the eIF-2B alpha beta delta subunits family	tif2Ba	-	-	-	-	-	-	-	-	-	-	-	IF-2B,NUDIX
k59_47582_1	1304888.ATWF01000002_gene308	8.31e-48	173.0	COG0265@1|root,COG0308@1|root,COG3016@1|root,COG0265@2|Bacteria,COG0308@2|Bacteria,COG3016@2|Bacteria,2GFIT@200930|Deferribacteres	200930|Deferribacteres	EO	Peptidase family M1 domain	-	-	-	-	-	-	-	-	-	-	-	-	Cofac_haem_bdg,PDZ_2,Peptidase_M1
k59_32286_1	1121127.JAFA01000005_gene4763	1.12e-08	63.5	COG2378@1|root,COG2378@2|Bacteria,1QYA2@1224|Proteobacteria,2VMMT@28216|Betaproteobacteria,1K5TK@119060|Burkholderiaceae	28216|Betaproteobacteria	K	WYL domain	-	-	-	-	-	-	-	-	-	-	-	-	WYL
k59_100695_1	1121405.dsmv_2792	7.01e-57	184.0	COG1102@1|root,COG1102@2|Bacteria,1N69V@1224|Proteobacteria,42UCK@68525|delta/epsilon subdivisions,2WQ7M@28221|Deltaproteobacteria,2MKKM@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Cytidylate kinase-like family	-	-	-	-	-	-	-	-	-	-	-	-	Cytidylate_kin2
k59_161388_1	1121272.KB903272_gene29	3.9e-27	112.0	COG0639@1|root,COG0639@2|Bacteria,2I2UI@201174|Actinobacteria,4DMD5@85008|Micromonosporales	201174|Actinobacteria	T	RNA ligase	-	-	6.5.1.3	ko:K14680	-	-	-	-	ko00000,ko01000	-	-	-	RNA_lig_T4_1
k59_100697_1	882.DVU_0126	4.39e-24	104.0	COG0842@1|root,COG1131@1|root,COG0842@2|Bacteria,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,42MV1@68525|delta/epsilon subdivisions,2WK9W@28221|Deltaproteobacteria,2MA8B@213115|Desulfovibrionales	28221|Deltaproteobacteria	V	pfam abc	-	-	-	ko:K01990,ko:K01992,ko:K09695	ko02010,map02010	M00252,M00254	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.102	-	-	ABC2_membrane_3,ABC_tran
k59_100697_2	338966.Ppro_2904	1.93e-21	92.4	COG0845@1|root,COG0845@2|Bacteria,1MUG6@1224|Proteobacteria,42R8A@68525|delta/epsilon subdivisions,2WM6Z@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM secretion protein HlyD family protein	-	-	-	ko:K01993	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_D23
k59_199159_1	675812.VHA_001478	4.17e-06	55.8	COG1674@1|root,COG1674@2|Bacteria,1MVPI@1224|Proteobacteria,1RM9A@1236|Gammaproteobacteria,1XUE7@135623|Vibrionales	135623|Vibrionales	D	COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins	ftsK	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
k59_153862_1	1123261.AXDW01000005_gene2503	1e-23	103.0	COG0750@1|root,COG0750@2|Bacteria,1MU91@1224|Proteobacteria,1RMIX@1236|Gammaproteobacteria,1X3KG@135614|Xanthomonadales	135614|Xanthomonadales	M	zinc metalloprotease	rseP	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_M50
k59_24698_1	246194.CHY_1547	1.8e-39	149.0	COG3829@1|root,COG4624@1|root,COG3829@2|Bacteria,COG4624@2|Bacteria,1TP0E@1239|Firmicutes,247MB@186801|Clostridia,42F02@68295|Thermoanaerobacterales	186801|Clostridia	K	transcriptional regulator	-	-	-	ko:K03721	-	-	-	-	ko00000,ko03000	-	-	-	FeS,Fe_hyd_lg_C,Fer4,HTH_8,PAS,PAS_4,PAS_9,PTS-HPr,Sigma54_activat
k59_1957_1	96561.Dole_0623	1.45e-34	128.0	COG0642@1|root,COG2205@2|Bacteria,1RK25@1224|Proteobacteria,42T3D@68525|delta/epsilon subdivisions,2WMAT@28221|Deltaproteobacteria,2MI6G@213118|Desulfobacterales	28221|Deltaproteobacteria	T	PFAM ATP-binding region ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
k59_153863_1	1265505.ATUG01000001_gene4058	1.83e-43	152.0	COG4177@1|root,COG4177@2|Bacteria,1MV66@1224|Proteobacteria,42MTH@68525|delta/epsilon subdivisions,2WJQY@28221|Deltaproteobacteria,2MK6I@213118|Desulfobacterales	28221|Deltaproteobacteria	E	PFAM inner-membrane translocator	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
k59_153863_2	1265505.ATUG01000001_gene4057	1.58e-75	233.0	COG0559@1|root,COG0559@2|Bacteria,1N54M@1224|Proteobacteria,42PNV@68525|delta/epsilon subdivisions,2WJVJ@28221|Deltaproteobacteria,2MK8B@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Branched-chain amino acid transport system / permease component	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
k59_206851_1	420247.Msm_1279	1.06e-07	53.1	COG1545@1|root,arCOG01285@2157|Archaea,2XXGF@28890|Euryarchaeota,23P3X@183925|Methanobacteria	183925|Methanobacteria	V	DUF35 OB-fold domain, acyl-CoA-associated	-	-	-	ko:K07068	-	-	-	-	ko00000	-	-	-	DUF35_N,OB_aCoA_assoc
k59_206851_2	1121422.AUMW01000009_gene3327	2.27e-32	122.0	COG0183@1|root,COG0183@2|Bacteria,1TT8U@1239|Firmicutes,24AD9@186801|Clostridia,263K7@186807|Peptococcaceae	186801|Clostridia	I	Thiolase, C-terminal domain	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	DUF35_N,Thiolase_C,Thiolase_N,ketoacyl-synt
k59_214247_1	186497.PF1638	2.05e-43	152.0	COG1355@1|root,arCOG01728@2157|Archaea,2XVYU@28890|Euryarchaeota,2435M@183968|Thermococci	183968|Thermococci	S	Belongs to the MEMO1 family	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0032886,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0065007	-	ko:K06990	-	-	-	-	ko00000,ko04812	-	-	-	Memo
k59_229456_1	309799.DICTH_0721	1.83e-66	225.0	COG2804@1|root,COG2804@2|Bacteria	2|Bacteria	NU	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB	ctsE	-	-	ko:K02454,ko:K02652	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSE,T2SSE_N
k59_32299_1	1499967.BAYZ01000009_gene5393	1.38e-143	418.0	COG2718@1|root,COG2718@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF444)	yhbH	-	-	ko:K09786	-	-	-	-	ko00000	-	-	-	DUF444,Haem_oxygenas_2
k59_62757_2	1121405.dsmv_0106	3.58e-63	197.0	COG3005@1|root,COG3005@2|Bacteria,1RIC0@1224|Proteobacteria,42NW0@68525|delta/epsilon subdivisions,2WK0R@28221|Deltaproteobacteria,2MJCY@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM NapC NirT cytochrome c	-	-	-	ko:K02569,ko:K03532	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	5.A.3.4	-	-	Cytochrom_NNT
k59_40009_1	880072.Desac_0171	3.79e-65	207.0	COG0496@1|root,COG0496@2|Bacteria,1MVHE@1224|Proteobacteria,42N0I@68525|delta/epsilon subdivisions,2WMUX@28221|Deltaproteobacteria,2MQHN@213462|Syntrophobacterales	28221|Deltaproteobacteria	F	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates	surE	-	3.1.3.5	ko:K03787	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	SurE
k59_70225_1	335543.Sfum_3193	5.73e-06	53.5	COG0859@1|root,COG0859@2|Bacteria,1NABN@1224|Proteobacteria,42V15@68525|delta/epsilon subdivisions,2WRJN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM glycosyl transferase family 9	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_9
k59_183918_1	1432050.IE4771_CH01153	1.23e-74	234.0	COG4977@1|root,COG4977@2|Bacteria,1MUDK@1224|Proteobacteria,2U1C5@28211|Alphaproteobacteria,4BC24@82115|Rhizobiaceae	28211|Alphaproteobacteria	K	Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain	-	-	-	-	-	-	-	-	-	-	-	-	DJ-1_PfpI,HTH_18
k59_214255_1	1121403.AUCV01000004_gene2002	4.55e-36	127.0	COG1592@1|root,COG1592@2|Bacteria,1R9WG@1224|Proteobacteria,42N9V@68525|delta/epsilon subdivisions,2WJWQ@28221|Deltaproteobacteria,2MHUF@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM Rubrerythrin	-	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
k59_214255_2	933262.AXAM01000083_gene767	2e-25	95.9	2CCKF@1|root,334IH@2|Bacteria,1NDED@1224|Proteobacteria,42VZE@68525|delta/epsilon subdivisions,2WRMN@28221|Deltaproteobacteria,2MM08@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_206863_1	1121405.dsmv_3401	1.27e-36	139.0	COG1032@1|root,COG1032@2|Bacteria,1MU15@1224|Proteobacteria,42N12@68525|delta/epsilon subdivisions,2WK0X@28221|Deltaproteobacteria,2MI8S@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
k59_54671_1	96561.Dole_0613	1.58e-30	120.0	2EN50@1|root,33FT1@2|Bacteria,1NIJS@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_130606_2	1232410.KI421423_gene1872	5.84e-47	159.0	COG1924@1|root,COG1924@2|Bacteria,1RDZA@1224|Proteobacteria,42RYS@68525|delta/epsilon subdivisions,2WNJX@28221|Deltaproteobacteria,43T2B@69541|Desulfuromonadales	28221|Deltaproteobacteria	I	BadF/BadG/BcrA/BcrD ATPase family	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG
k59_107663_1	335543.Sfum_1586	2.18e-68	219.0	COG0142@1|root,COG0142@2|Bacteria,1MUK6@1224|Proteobacteria,42M1B@68525|delta/epsilon subdivisions,2WK2M@28221|Deltaproteobacteria,2MQBX@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	Belongs to the FPP GGPP synthase family	ispB	-	2.5.1.1,2.5.1.10,2.5.1.29,2.5.1.90	ko:K02523,ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00366	R01658,R02003,R02061,R09248	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
k59_145699_1	502025.Hoch_3072	2.79e-61	205.0	COG1070@1|root,COG1070@2|Bacteria,1MW4A@1224|Proteobacteria,42Q1B@68525|delta/epsilon subdivisions,2WKJH@28221|Deltaproteobacteria,2YU85@29|Myxococcales	28221|Deltaproteobacteria	G	FGGY family of carbohydrate kinases, N-terminal domain	-	-	2.7.1.17	ko:K00854	ko00040,ko01100,map00040,map01100	M00014	R01639	RC00002,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	-	FGGY_C,FGGY_N
k59_153394_1	1322246.BN4_11219	1.05e-92	279.0	COG2169@1|root,COG2169@2|Bacteria,1QTXR@1224|Proteobacteria	1224|Proteobacteria	K	AraC family transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,Cupin_2,HTH_18
k59_122978_1	1396418.BATQ01000189_gene762	2.56e-34	131.0	COG3344@1|root,COG3344@2|Bacteria,46TQ6@74201|Verrucomicrobia	74201|Verrucomicrobia	L	PFAM RNA-directed DNA polymerase (Reverse transcriptase)	-	-	-	-	-	-	-	-	-	-	-	-	GIIM,RVT_1
k59_62368_1	1121405.dsmv_0482	2.79e-47	156.0	COG0355@1|root,COG0355@2|Bacteria,1RHE4@1224|Proteobacteria,42TII@68525|delta/epsilon subdivisions,2WPVK@28221|Deltaproteobacteria,2MK6Z@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpC	GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_DE,ATP-synt_DE_N
k59_62368_2	96561.Dole_0603	1.74e-116	346.0	COG0055@1|root,COG0055@2|Bacteria,1MUFU@1224|Proteobacteria,42KZA@68525|delta/epsilon subdivisions,2WJ1V@28221|Deltaproteobacteria,2MI99@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
k59_176024_1	1121448.DGI_2578	2.4e-10	64.7	COG0784@1|root,COG0784@2|Bacteria,1R0J3@1224|Proteobacteria,43CY3@68525|delta/epsilon subdivisions,2WRP4@28221|Deltaproteobacteria,2MHC6@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	zinc-ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	zinc_ribbon_4
k59_176024_2	335543.Sfum_1694	2.51e-26	106.0	COG2805@1|root,COG2805@2|Bacteria,1MU3J@1224|Proteobacteria,42M7F@68525|delta/epsilon subdivisions,2WJ4Z@28221|Deltaproteobacteria,2MR4Y@213462|Syntrophobacterales	28221|Deltaproteobacteria	NU	Type IV secretion-system coupling protein DNA-binding domain	pilT1	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
k59_92550_1	999423.HMPREF9161_00982	2.44e-27	108.0	COG0517@1|root,COG0517@2|Bacteria,1V0XU@1239|Firmicutes,4H33K@909932|Negativicutes	909932|Negativicutes	S	CBS domain	acuB	-	-	ko:K04767	-	-	-	-	ko00000	-	-	-	ACT,CBS
k59_24353_2	330214.NIDE3435	8.91e-66	212.0	COG1131@1|root,COG1131@2|Bacteria,3J122@40117|Nitrospirae	40117|Nitrospirae	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
k59_92552_1	1121405.dsmv_2227	2.14e-116	354.0	28HQ2@1|root,2Z7XV@2|Bacteria,1P4Z7@1224|Proteobacteria,42NSG@68525|delta/epsilon subdivisions,2WJ6K@28221|Deltaproteobacteria,2MJCF@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_206413_2	626887.J057_23810	3.03e-60	192.0	2DC7W@1|root,2ZD7C@2|Bacteria,1QU8S@1224|Proteobacteria,1S6MA@1236|Gammaproteobacteria,46BPC@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Chalcone isomerase-like	-	-	-	-	-	-	-	-	-	-	-	-	Chalcone_3
k59_122999_1	1167006.UWK_02601	2.83e-25	107.0	COG0427@1|root,COG1670@1|root,COG0427@2|Bacteria,COG1670@2|Bacteria,1MUGE@1224|Proteobacteria,42MHC@68525|delta/epsilon subdivisions,2WINZ@28221|Deltaproteobacteria,2MI87@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM Acetyl-CoA hydrolase transferase	-	-	-	-	-	-	-	-	-	-	-	-	AcetylCoA_hyd_C,AcetylCoA_hydro,Acetyltransf_1,Acetyltransf_3
k59_47207_1	1121396.KB893077_gene741	4.36e-61	204.0	COG2152@1|root,COG2152@2|Bacteria,1MX8M@1224|Proteobacteria,42YYU@68525|delta/epsilon subdivisions,2WU8G@28221|Deltaproteobacteria,2MN6U@213118|Desulfobacterales	28221|Deltaproteobacteria	G	Pfam:DUF377	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_130
k59_39608_1	644282.Deba_1864	8.19e-76	240.0	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,42M0D@68525|delta/epsilon subdivisions,2WK8T@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	Belongs to the thiolase family	-	-	2.3.1.16	ko:K00632	ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212	M00087,M00113	R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955	ko00000,ko00001,ko00002,ko01000	-	-	-	Thiolase_C,Thiolase_N
k59_100232_2	1499967.BAYZ01000171_gene5607	4.49e-07	55.5	COG0484@1|root,COG0484@2|Bacteria	2|Bacteria	O	heat shock protein binding	-	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
k59_213873_1	1265505.ATUG01000001_gene3589	1.17e-55	198.0	COG1148@1|root,COG1148@2|Bacteria,1QUM4@1224|Proteobacteria,42MPP@68525|delta/epsilon subdivisions,2WJ3U@28221|Deltaproteobacteria,2MMQ1@213118|Desulfobacterales	28221|Deltaproteobacteria	C	NAD(P)-binding Rossmann-like domain	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_6,Pyr_redox_2
k59_92563_1	56780.SYN_00075	3.02e-59	207.0	COG0031@1|root,COG0215@1|root,COG0031@2|Bacteria,COG0215@2|Bacteria,1MUBE@1224|Proteobacteria,42M6M@68525|delta/epsilon subdivisions,2WIQM@28221|Deltaproteobacteria,2MR3Q@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	Pyridoxal-phosphate dependent enzyme	cysM	-	2.5.1.47,6.1.1.16	ko:K01738,ko:K01883,ko:K12339	ko00270,ko00920,ko00970,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map00970,map01100,map01110,map01120,map01130,map01200,map01230	M00021,M00359,M00360	R00897,R03132,R03601,R03650,R04859	RC00020,RC00055,RC00523,RC02814,RC02821,RC02876	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,PALP,tRNA-synt_1e
k59_84946_1	1358423.N180_16555	8.02e-06	46.2	COG0724@1|root,COG0724@2|Bacteria,4NUIS@976|Bacteroidetes,1ITB6@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
k59_100235_1	3641.EOX92582	7.62e-46	164.0	COG0123@1|root,KOG1343@2759|Eukaryota,37N54@33090|Viridiplantae,3GEM7@35493|Streptophyta	35493|Streptophyta	B	histone deacetylase	-	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005829,GO:0006464,GO:0006476,GO:0006807,GO:0008092,GO:0008150,GO:0008152,GO:0009507,GO:0009536,GO:0009987,GO:0015631,GO:0016787,GO:0016810,GO:0016811,GO:0019213,GO:0019538,GO:0019899,GO:0019902,GO:0019903,GO:0033558,GO:0035601,GO:0036211,GO:0042903,GO:0043014,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043412,GO:0043621,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0048487,GO:0051721,GO:0071704,GO:0090042,GO:0098732,GO:0140096,GO:1901564	-	-	-	-	-	-	-	-	-	-	Hist_deacetyl
k59_77615_1	1121405.dsmv_2552	1.06e-105	317.0	COG0174@1|root,COG0174@2|Bacteria,1MUGQ@1224|Proteobacteria,42M7A@68525|delta/epsilon subdivisions,2WJ8P@28221|Deltaproteobacteria,2MHRE@213118|Desulfobacterales	28221|Deltaproteobacteria	E	TIGRFAM glutamine synthetase, type I	glnA	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
k59_16707_1	85643.Tmz1t_3892	2.52e-57	197.0	COG5421@1|root,COG5421@2|Bacteria,1R3NX@1224|Proteobacteria,2VZHX@28216|Betaproteobacteria	28216|Betaproteobacteria	L	Transposase, IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
k59_16708_1	933262.AXAM01000083_gene769	1.76e-120	362.0	COG0445@1|root,COG0445@2|Bacteria,1MU6F@1224|Proteobacteria,42KZC@68525|delta/epsilon subdivisions,2WJ31@28221|Deltaproteobacteria,2MJBM@213118|Desulfobacterales	28221|Deltaproteobacteria	D	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34	gidA	GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363	-	ko:K03495	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko03016,ko03036	-	-	-	GIDA,GIDA_assoc
k59_198789_1	1265505.ATUG01000002_gene1718	3.01e-47	167.0	COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,43AZ5@68525|delta/epsilon subdivisions,2X6DH@28221|Deltaproteobacteria,2MPHT@213118|Desulfobacterales	1224|Proteobacteria	KT	Bacterial regulatory protein, Fis family	-	-	-	ko:K06714	-	-	-	-	ko00000,ko03000	-	-	-	HTH_8,PAS_4,PAS_9,Sigma54_activat
k59_130629_2	335543.Sfum_2771	3.46e-39	139.0	arCOG13273@1|root,33MKU@2|Bacteria,1PAEN@1224|Proteobacteria,432F9@68525|delta/epsilon subdivisions,2WY9V@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_213885_1	349161.Dred_1192	5.12e-43	157.0	COG0553@1|root,COG0553@2|Bacteria,1TP2C@1239|Firmicutes,24DVA@186801|Clostridia	186801|Clostridia	L	DEAD-like helicases superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,N6_N4_Mtase,SNF2_N
k59_213885_2	1089548.KI783301_gene2629	9.1e-44	152.0	COG0863@1|root,COG0863@2|Bacteria,1UZIN@1239|Firmicutes,4HU16@91061|Bacilli	91061|Bacilli	L	DNA methylase	-	-	-	-	-	-	-	-	-	-	-	-	N6_N4_Mtase
k59_62404_1	269799.Gmet_0956	6.17e-100	314.0	COG0525@1|root,COG0525@2|Bacteria,1MV7B@1224|Proteobacteria,42MPZ@68525|delta/epsilon subdivisions,2WIR9@28221|Deltaproteobacteria,43TAT@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
k59_54733_1	180332.JTGN01000007_gene3716	5.85e-53	174.0	COG1396@1|root,COG1396@2|Bacteria,1V1K5@1239|Firmicutes,24FTC@186801|Clostridia	186801|Clostridia	K	domain protein	puuR	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,HTH_19,HTH_3
k59_1556_1	1379698.RBG1_1C00001G0159	2.49e-58	195.0	COG2204@1|root,COG2204@2|Bacteria	2|Bacteria	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
k59_39635_1	177437.HRM2_04880	6.02e-111	341.0	COG2414@1|root,COG2414@2|Bacteria,1R76Y@1224|Proteobacteria,42QE3@68525|delta/epsilon subdivisions,2WIIW@28221|Deltaproteobacteria,2MIUU@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Aldehyde ferredoxin oxidoreductase, N-terminal domain	-	-	1.2.7.5	ko:K03738	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00309	R08571	RC00242	ko00000,ko00001,ko00002,ko01000	-	-	-	AFOR_C,AFOR_N
k59_176044_1	1033738.CAEP01000143_gene1179	1.21e-08	55.1	COG0410@1|root,COG0410@2|Bacteria,1TPW4@1239|Firmicutes,4HABJ@91061|Bacilli,26D96@186818|Planococcaceae	91061|Bacilli	E	ATPases associated with a variety of cellular activities	livF	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
k59_176044_2	485913.Krac_9797	7.85e-41	146.0	COG0411@1|root,COG0411@2|Bacteria,2G5W6@200795|Chloroflexi	200795|Chloroflexi	E	PFAM ABC transporter related	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
k59_92576_1	933115.GPDM_12182	2.61e-07	57.8	COG4856@1|root,COG4856@2|Bacteria,1TSIV@1239|Firmicutes,4HD8Y@91061|Bacilli,26DTB@186818|Planococcaceae	91061|Bacilli	S	protein conserved in bacteria	ybbR	GO:0008150,GO:0031279,GO:0031281,GO:0043085,GO:0044093,GO:0045761,GO:0045762,GO:0050790,GO:0051339,GO:0051349,GO:0065007,GO:0065009	-	-	-	-	-	-	-	-	-	-	YbbR
k59_9223_1	880072.Desac_0834	4.8e-112	351.0	COG1145@1|root,COG1148@1|root,COG1145@2|Bacteria,COG1148@2|Bacteria,1QUM4@1224|Proteobacteria,42MPP@68525|delta/epsilon subdivisions,2WJ3U@28221|Deltaproteobacteria,2MQVU@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	4Fe-4S ferredoxin iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_20,Pyr_redox_2
k59_77643_1	1200792.AKYF01000011_gene3443	5.41e-50	172.0	COG0743@1|root,COG0743@2|Bacteria,1TP1C@1239|Firmicutes,4HBAV@91061|Bacilli,26S2E@186822|Paenibacillaceae	91061|Bacilli	I	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)	dxr	-	1.1.1.267	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05688	RC01452	ko00000,ko00001,ko00002,ko01000	-	-	-	DXPR_C,DXP_redisom_C,DXP_reductoisom
k59_69840_1	118797.XP_007446469.1	4.2e-39	142.0	COG0846@1|root,KOG2684@2759|Eukaryota,38EG6@33154|Opisthokonta,3BC0K@33208|Metazoa,3CRV9@33213|Bilateria,4898J@7711|Chordata,48ZY9@7742|Vertebrata,3J5J0@40674|Mammalia,4J5NE@91561|Cetartiodactyla	33208|Metazoa	BK	NAD-dependent protein deacylase sirtuin-5, mitochondrial	SIRT5	GO:0000166,GO:0003674,GO:0003824,GO:0003950,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005758,GO:0005759,GO:0005829,GO:0006325,GO:0006342,GO:0006355,GO:0006464,GO:0006471,GO:0006476,GO:0006807,GO:0006996,GO:0007005,GO:0008150,GO:0008152,GO:0008270,GO:0009605,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0009991,GO:0010468,GO:0010556,GO:0010558,GO:0010565,GO:0010566,GO:0010605,GO:0010629,GO:0010656,GO:0010660,GO:0010662,GO:0010664,GO:0010665,GO:0010667,GO:0010941,GO:0016020,GO:0016043,GO:0016458,GO:0016740,GO:0016757,GO:0016763,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018205,GO:0019213,GO:0019219,GO:0019222,GO:0019538,GO:0019866,GO:0031090,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031667,GO:0031966,GO:0031967,GO:0031970,GO:0031974,GO:0031975,GO:0033558,GO:0034979,GO:0035601,GO:0036046,GO:0036047,GO:0036048,GO:0036049,GO:0036054,GO:0036055,GO:0036094,GO:0036211,GO:0040029,GO:0042981,GO:0043066,GO:0043067,GO:0043069,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0045814,GO:0045892,GO:0045934,GO:0046872,GO:0046914,GO:0048037,GO:0048519,GO:0048523,GO:0050662,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051276,GO:0051287,GO:0060255,GO:0060548,GO:0061697,GO:0061698,GO:0061699,GO:0062012,GO:0065007,GO:0070013,GO:0070403,GO:0071704,GO:0071840,GO:0080090,GO:0097159,GO:0098732,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2000377,GO:2000378,GO:2001141	-	ko:K11415	-	-	-	-	ko00000,ko01000,ko03036	-	-	-	SIR2
k59_115217_1	1121405.dsmv_0392	1.45e-36	135.0	COG0394@1|root,COG0655@1|root,COG0394@2|Bacteria,COG0655@2|Bacteria,1NANP@1224|Proteobacteria,42Q16@68525|delta/epsilon subdivisions,2WIJ7@28221|Deltaproteobacteria,2MIC1@213118|Desulfobacterales	28221|Deltaproteobacteria	T	PFAM NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red,LMWPc
k59_115219_1	525897.Dbac_1064	3.92e-32	129.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42NNT@68525|delta/epsilon subdivisions,2WJDP@28221|Deltaproteobacteria,2M8A1@213115|Desulfovibrionales	28221|Deltaproteobacteria	NT	histidine kinase HAMP region domain protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	DUF3365,HAMP,MCPsignal,dCache_1
k59_153451_1	1121405.dsmv_2533	6e-79	237.0	COG2606@1|root,COG2606@2|Bacteria,1R9YR@1224|Proteobacteria,42SA8@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	YbaK proline--tRNA ligase associated domain protein	yeaK	GO:0002161,GO:0002196,GO:0003674,GO:0003824,GO:0006139,GO:0006399,GO:0006417,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0016070,GO:0016787,GO:0016788,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0034248,GO:0034250,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0045727,GO:0045903,GO:0046483,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0052689,GO:0060255,GO:0065007,GO:0065008,GO:0071704,GO:0080090,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360,GO:2000112	-	ko:K19055	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA_edit
k59_31940_1	1278971.AOGF01000045_gene639	3.1e-25	105.0	COG3676@1|root,COG3676@2|Bacteria,1QTF7@1224|Proteobacteria,1SZQV@1236|Gammaproteobacteria,1YAXA@135625|Pasteurellales	1236|Gammaproteobacteria	L	ISXO2-like transposase domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS1595
k59_229127_1	1121405.dsmv_1235	4.99e-83	252.0	COG0412@1|root,COG0412@2|Bacteria,1NKIB@1224|Proteobacteria,43B7J@68525|delta/epsilon subdivisions,2X6KZ@28221|Deltaproteobacteria,2MMAU@213118|Desulfobacterales	28221|Deltaproteobacteria	Q	Dienelactone hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	DLH
k59_191200_1	1125863.JAFN01000001_gene3488	3.42e-89	281.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,42M5F@68525|delta/epsilon subdivisions,2WISF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	IQ	PFAM AMP-dependent synthetase and ligase	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
k59_100288_1	1121405.dsmv_3645	5.27e-134	418.0	COG0085@1|root,COG0085@2|Bacteria,1MUC4@1224|Proteobacteria,43DMZ@68525|delta/epsilon subdivisions,2WIW5@28221|Deltaproteobacteria,2MI5C@213118|Desulfobacterales	28221|Deltaproteobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
k59_108221_1	686340.Metal_0724	3.88e-22	92.8	COG3293@1|root,COG3385@1|root,COG3293@2|Bacteria,COG3385@2|Bacteria,1RBFK@1224|Proteobacteria,1S22S@1236|Gammaproteobacteria,1XGGK@135618|Methylococcales	135618|Methylococcales	L	PFAM Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DUF4096
k59_62875_1	1232410.KI421421_gene3541	2.58e-38	133.0	COG4103@1|root,COG4103@2|Bacteria,1N6YZ@1224|Proteobacteria,42WGY@68525|delta/epsilon subdivisions,2WS4W@28221|Deltaproteobacteria,43VDK@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Tellurite resistance protein TerB	-	-	-	-	-	-	-	-	-	-	-	-	TerB
k59_229568_1	177437.HRM2_19280	7.99e-92	276.0	COG3267@1|root,COG3267@2|Bacteria,1Q4DA@1224|Proteobacteria,42YYB@68525|delta/epsilon subdivisions,2WU9J@28221|Deltaproteobacteria	28221|Deltaproteobacteria	U	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22
k59_161530_1	388413.ALPR1_04975	1.43e-16	78.2	COG0500@1|root,COG2226@2|Bacteria,4NE6P@976|Bacteroidetes,47K6K@768503|Cytophagia	976|Bacteroidetes	Q	Methyltransferase domain	rebM	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
k59_70342_1	1117315.AHCA01000010_gene997	2.86e-271	748.0	COG3119@1|root,COG3119@2|Bacteria,1P73G@1224|Proteobacteria,1RYE9@1236|Gammaproteobacteria,2Q4SR@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	P	PFAM sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4994,Sulfatase,Sulfatase_C
k59_131154_1	1047013.AQSP01000137_gene548	1.46e-85	270.0	COG2203@1|root,COG2206@1|root,COG2203@2|Bacteria,COG2206@2|Bacteria,2NS55@2323|unclassified Bacteria	2|Bacteria	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HD,HD_5,PAS_4,PAS_9,PocR
k59_40148_1	335543.Sfum_1174	4.97e-38	127.0	COG1908@1|root,COG1908@2|Bacteria,1NFTQ@1224|Proteobacteria,42VFD@68525|delta/epsilon subdivisions,2WS6S@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Methyl-viologen-reducing hydrogenase, delta subunit	-	-	-	-	-	-	-	-	-	-	-	-	FlpD
k59_40148_2	335543.Sfum_1175	2.33e-19	79.3	COG1908@1|root,COG1908@2|Bacteria,1NM99@1224|Proteobacteria,42X5B@68525|delta/epsilon subdivisions,2WTHK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Methyl-viologen-reducing hydrogenase, delta subunit	-	-	-	-	-	-	-	-	-	-	-	-	FlpD
k59_115658_1	28229.ND2E_2529	2.24e-09	60.8	COG1392@1|root,COG1392@2|Bacteria,1MXY9@1224|Proteobacteria,1RQHT@1236|Gammaproteobacteria,2Q6KN@267889|Colwelliaceae	1236|Gammaproteobacteria	P	Protein of unknown function DUF47	VY92_08315	-	-	ko:K07220	-	-	-	-	ko00000	-	-	-	PhoU_div
k59_115658_2	1121405.dsmv_0098	5.56e-53	178.0	COG0306@1|root,COG0306@2|Bacteria,1MVXK@1224|Proteobacteria,42MYT@68525|delta/epsilon subdivisions,2WM6R@28221|Deltaproteobacteria,2MI10@213118|Desulfobacterales	28221|Deltaproteobacteria	P	PFAM phosphate transporter	-	-	-	ko:K03306	-	-	-	-	ko00000	2.A.20	-	-	PHO4
k59_168775_1	96561.Dole_0073	6.53e-80	246.0	COG0074@1|root,COG0074@2|Bacteria,1MUGA@1224|Proteobacteria,42M2W@68525|delta/epsilon subdivisions,2WJBV@28221|Deltaproteobacteria,2MJ9I@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit	sucD	-	6.2.1.5	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,CoA_binding,Ligase_CoA
k59_222133_1	76114.ebA5622	4.56e-38	146.0	COG0243@1|root,COG0243@2|Bacteria,1P01N@1224|Proteobacteria,2VKSY@28216|Betaproteobacteria,2KVC6@206389|Rhodocyclales	206389|Rhodocyclales	C	Molybdopterin oxidoreductase Fe4S4 domain	-	-	-	-	-	-	-	-	-	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
k59_9820_1	236097.ADG881_822	5.02e-74	236.0	COG5361@1|root,COG5361@2|Bacteria,1NX2A@1224|Proteobacteria,1RZYZ@1236|Gammaproteobacteria,1XPPQ@135619|Oceanospirillales	135619|Oceanospirillales	S	Protein of unknown function (DUF1254)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1214,DUF1254
k59_184056_1	335543.Sfum_2362	3.63e-08	62.0	COG1345@1|root,COG2931@1|root,COG1345@2|Bacteria,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,42R1I@68525|delta/epsilon subdivisions,2WMVI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	Q	COG2931, RTX toxins and related Ca2 -binding proteins	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	DUF4215
k59_24847_1	1121403.AUCV01000018_gene3230	1.63e-08	64.3	COG0834@1|root,COG2199@1|root,COG0834@2|Bacteria,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,42MNN@68525|delta/epsilon subdivisions,2WKGY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Bacterial periplasmic substrate-binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,SBP_bac_3
k59_2099_1	1232437.KL662031_gene2544	1.78e-116	346.0	COG2367@1|root,COG2367@2|Bacteria,1R4Y9@1224|Proteobacteria,42YC9@68525|delta/epsilon subdivisions,2WTSH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_93074_1	913865.DOT_1769	1.65e-127	372.0	COG4974@1|root,COG4974@2|Bacteria,1U0MD@1239|Firmicutes,24FWH@186801|Clostridia,261AT@186807|Peptococcaceae	186801|Clostridia	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_1,Phage_int_SAM_4,Phage_integrase
k59_62889_1	323848.Nmul_A2564	4.13e-61	192.0	COG0512@1|root,COG0512@2|Bacteria,1MV5Y@1224|Proteobacteria,2VHGQ@28216|Betaproteobacteria,371WE@32003|Nitrosomonadales	28216|Betaproteobacteria	EH	PFAM Glutamine amidotransferase class-I	trpG	-	4.1.3.27	ko:K01658	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
k59_70347_1	1236541.BALL01000045_gene4073	1.35e-51	178.0	28I8B@1|root,2Z8B5@2|Bacteria,1MUNM@1224|Proteobacteria,1RQ1H@1236|Gammaproteobacteria,2Q8W2@267890|Shewanellaceae	1236|Gammaproteobacteria	C	Cytochrome c bacterial	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554,Cytochrome_cB
k59_174922_1	999419.HMPREF1077_03002	9.3e-33	118.0	COG1725@1|root,COG1725@2|Bacteria,4NT1X@976|Bacteroidetes,2FTX9@200643|Bacteroidia,22YHZ@171551|Porphyromonadaceae	976|Bacteroidetes	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	GntR
k59_61295_1	1121456.ATVA01000016_gene1968	1.28e-40	145.0	COG0619@1|root,COG0619@2|Bacteria,1RJIT@1224|Proteobacteria,42RU5@68525|delta/epsilon subdivisions,2WNB7@28221|Deltaproteobacteria,2MA26@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	TIGRFAM cobalt ABC transporter, inner membrane subunit CbiQ	cbiQ	-	-	ko:K02008	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	CbiQ
k59_212692_1	56780.SYN_00027	2.64e-17	80.5	COG0459@1|root,COG0459@2|Bacteria,1MURR@1224|Proteobacteria,42M52@68525|delta/epsilon subdivisions,2WIRK@28221|Deltaproteobacteria,2MRAR@213462|Syntrophobacterales	28221|Deltaproteobacteria	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	-	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
k59_212692_2	909663.KI867151_gene3126	1.88e-44	145.0	COG0234@1|root,COG0234@2|Bacteria,1MZ2X@1224|Proteobacteria,42U7E@68525|delta/epsilon subdivisions,2WPZP@28221|Deltaproteobacteria,2MS29@213462|Syntrophobacterales	28221|Deltaproteobacteria	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
k59_488_1	439235.Dalk_1330	3.99e-64	209.0	COG3464@1|root,COG3464@2|Bacteria,1PFY7@1224|Proteobacteria,4377W@68525|delta/epsilon subdivisions,2X29U@28221|Deltaproteobacteria,2MP93@213118|Desulfobacterales	28221|Deltaproteobacteria	L	Helix-turn-helix domain of transposase family ISL3	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISL3,HTH_Tnp_ISL3
k59_488_2	439235.Dalk_1330	1.88e-15	76.6	COG3464@1|root,COG3464@2|Bacteria,1PFY7@1224|Proteobacteria,4377W@68525|delta/epsilon subdivisions,2X29U@28221|Deltaproteobacteria,2MP93@213118|Desulfobacterales	28221|Deltaproteobacteria	L	Helix-turn-helix domain of transposase family ISL3	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISL3,HTH_Tnp_ISL3
k59_144515_1	392500.Swoo_2821	4.67e-59	194.0	COG3938@1|root,COG3938@2|Bacteria,1N02K@1224|Proteobacteria,1RRIB@1236|Gammaproteobacteria,2Q9AM@267890|Shewanellaceae	1236|Gammaproteobacteria	E	Belongs to the proline racemase family	-	-	5.1.1.4	ko:K01777	ko00330,ko01100,map00330,map01100	-	R01255	RC00479	ko00000,ko00001,ko01000	-	-	-	Pro_racemase
k59_76329_1	338966.Ppro_0709	5.17e-59	203.0	COG5000@1|root,COG5000@2|Bacteria,1MWKZ@1224|Proteobacteria,42MCN@68525|delta/epsilon subdivisions,2WIYA@28221|Deltaproteobacteria,43TNJ@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	histidine kinase, HAMP	ntrY	-	2.7.13.3	ko:K13598	ko02020,map02020	M00498	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4
k59_83849_1	500635.MITSMUL_04809	2.2e-28	118.0	COG1032@1|root,COG5011@1|root,COG1032@2|Bacteria,COG5011@2|Bacteria,1TR2C@1239|Firmicutes,4H33G@909932|Negativicutes	909932|Negativicutes	C	Radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF2344,Radical_SAM
k59_91419_1	933262.AXAM01000213_gene1883	2.29e-58	182.0	2DN2Z@1|root,32V89@2|Bacteria,1N3VG@1224|Proteobacteria,42TI7@68525|delta/epsilon subdivisions,2WQNX@28221|Deltaproteobacteria,2MKM9@213118|Desulfobacterales	28221|Deltaproteobacteria	S	zinc-ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	zf-ribbon_3
k59_189987_1	1121405.dsmv_3225	7.7e-77	251.0	COG0031@1|root,COG0215@1|root,COG0031@2|Bacteria,COG0215@2|Bacteria,1MUBE@1224|Proteobacteria,42M6M@68525|delta/epsilon subdivisions,2WIQM@28221|Deltaproteobacteria,2MIN1@213118|Desulfobacterales	28221|Deltaproteobacteria	J	cysteinyl-tRNA synthetase	cysM	-	2.5.1.47,6.1.1.16	ko:K01738,ko:K01883,ko:K12339	ko00270,ko00920,ko00970,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map00970,map01100,map01110,map01120,map01130,map01200,map01230	M00021,M00359,M00360	R00897,R03132,R03601,R03650,R04859	RC00020,RC00055,RC00523,RC02814,RC02821,RC02876	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,PALP,tRNA-synt_1e
k59_99024_1	643562.Daes_2060	4.36e-63	210.0	COG0446@1|root,COG0607@1|root,COG0446@2|Bacteria,COG0607@2|Bacteria,1NR3M@1224|Proteobacteria,42N3G@68525|delta/epsilon subdivisions,2WIS9@28221|Deltaproteobacteria,2M89U@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	Pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Pyr_redox_dim,Rhodanese
k59_220479_1	1089553.Tph_c08010	3.65e-64	213.0	COG2801@1|root,COG3415@1|root,COG2801@2|Bacteria,COG3415@2|Bacteria,1TT8V@1239|Firmicutes,24BFH@186801|Clostridia,42ETS@68295|Thermoanaerobacterales	186801|Clostridia	L	PFAM Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_28,HTH_29,HTH_32,rve
k59_61310_1	1408473.JHXO01000009_gene3389	5.48e-87	263.0	COG3315@1|root,COG3315@2|Bacteria,4NKIE@976|Bacteroidetes,2G005@200643|Bacteroidia	976|Bacteroidetes	Q	Leucine carboxyl methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	LCM
k59_53576_1	335543.Sfum_3645	3.48e-28	110.0	COG1057@1|root,COG1057@2|Bacteria,1RD0J@1224|Proteobacteria,42SD9@68525|delta/epsilon subdivisions,2WPPN@28221|Deltaproteobacteria,2MQIZ@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_3200	CTP_transf_like
k59_220483_1	439235.Dalk_2439	2e-64	212.0	COG0402@1|root,COG0402@2|Bacteria,1MVPA@1224|Proteobacteria,42NI6@68525|delta/epsilon subdivisions,2WKI1@28221|Deltaproteobacteria,2MIIK@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine	mtaD	-	3.5.4.28,3.5.4.31	ko:K12960	ko00270,ko01100,map00270,map01100	-	R09660	RC00477	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
k59_76350_1	96561.Dole_1956	2.63e-124	361.0	COG0489@1|root,COG0489@2|Bacteria,1MU7R@1224|Proteobacteria,42NR0@68525|delta/epsilon subdivisions,2WIPG@28221|Deltaproteobacteria,2MHV5@213118|Desulfobacterales	28221|Deltaproteobacteria	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	-	-	-	-	-	-	-	-	-	-	-	-	ParA
k59_76350_2	1265505.ATUG01000003_gene496	9.65e-10	63.5	COG2905@1|root,COG2905@2|Bacteria,1MW8U@1224|Proteobacteria,42NAX@68525|delta/epsilon subdivisions,2WJF5@28221|Deltaproteobacteria,2MIA9@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Putative nucleotidyltransferase substrate binding domain	-	-	-	ko:K07182	-	-	-	-	ko00000	-	-	-	CBS,DUF294,DUF294_C,PAS_8,cNMP_binding,sCache_2
k59_137498_1	56780.SYN_02637	6.98e-131	383.0	COG2025@1|root,COG2025@2|Bacteria,1MUFI@1224|Proteobacteria,42M3T@68525|delta/epsilon subdivisions,2WIV8@28221|Deltaproteobacteria,2MR3X@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	Electron transfer flavoprotein FAD-binding domain	-	-	-	ko:K03522	-	-	-	-	ko00000,ko04147	-	-	-	ETF,ETF_alpha
k59_221025_1	96561.Dole_0775	1.17e-61	206.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,1MU1Q@1224|Proteobacteria,42ND6@68525|delta/epsilon subdivisions,2WIJS@28221|Deltaproteobacteria,2MHY5@213118|Desulfobacterales	28221|Deltaproteobacteria	G	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	Carb_kinase,YjeF_N
k59_198146_2	875328.JDM601_3235	5.74e-05	45.4	COG2261@1|root,COG2261@2|Bacteria,2GSMN@201174|Actinobacteria,239ZC@1762|Mycobacteriaceae	201174|Actinobacteria	S	Transglycosylase associated protein	-	-	-	-	-	-	-	-	-	-	-	-	Transgly_assoc
k59_190490_1	756067.MicvaDRAFT_1158	1.91e-14	74.3	COG1073@1|root,COG1073@2|Bacteria,1G1YP@1117|Cyanobacteria,1H80J@1150|Oscillatoriales	1117|Cyanobacteria	S	Alpha beta	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Hydrolase_4,PhoPQ_related
k59_190490_2	96561.Dole_2335	9.16e-11	65.5	COG0745@1|root,COG0745@2|Bacteria,1NE8H@1224|Proteobacteria,42NEH@68525|delta/epsilon subdivisions,2WK1M@28221|Deltaproteobacteria,2MHU4@213118|Desulfobacterales	28221|Deltaproteobacteria	T	PFAM response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Cytidylate_kin2,Response_reg
k59_152764_1	1304885.AUEY01000010_gene1685	9.46e-82	253.0	COG0451@1|root,COG0451@2|Bacteria,1MVI8@1224|Proteobacteria,42R49@68525|delta/epsilon subdivisions,2WNEZ@28221|Deltaproteobacteria,2MN63@213118|Desulfobacterales	28221|Deltaproteobacteria	M	NAD(P)H-binding	-	-	5.1.3.25	ko:K17947	ko00523,ko01130,map00523,map01130	-	R10279	RC00289	ko00000,ko00001,ko01000	-	-	-	Epimerase
k59_38991_1	335543.Sfum_2709	9.82e-80	253.0	COG0642@1|root,COG2205@2|Bacteria,1QHXX@1224|Proteobacteria,42NW1@68525|delta/epsilon subdivisions,2WJUF@28221|Deltaproteobacteria,2MR85@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	Histidine kinase-like ATPases	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
k59_198149_1	941449.dsx2_0659	2.45e-22	92.8	COG2204@1|root,COG2204@2|Bacteria,1RCHU@1224|Proteobacteria,42QWT@68525|delta/epsilon subdivisions,2WN23@28221|Deltaproteobacteria,2MAFK@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,STAS,STAS_2
k59_198149_2	1395516.PMO01_27550	0.000338	46.6	COG5002@1|root,COG5002@2|Bacteria,1QTV1@1224|Proteobacteria,1T1I6@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	member of a two-component regulatory system	irlS	-	2.7.13.3	ko:K07636,ko:K07644	ko02020,map02020	M00434,M00452,M00745	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022	-	-	-	HAMP,HATPase_c,HisKA
k59_16124_1	1499968.TCA2_4525	2.47e-36	140.0	2EZ4U@1|root,33SAZ@2|Bacteria,1VSTZ@1239|Firmicutes,4HT72@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Phage_capsid
k59_69254_1	439235.Dalk_2377	4.42e-82	251.0	COG1489@1|root,COG1489@2|Bacteria,1MUC3@1224|Proteobacteria,42QXT@68525|delta/epsilon subdivisions,2WN0R@28221|Deltaproteobacteria,2MJ9Y@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Belongs to the SfsA family	sfsA	-	-	ko:K06206	-	-	-	-	ko00000	-	-	-	SfsA
k59_137508_2	1089551.KE386572_gene3172	1.86e-67	227.0	COG2718@1|root,COG2718@2|Bacteria,1MWQM@1224|Proteobacteria,2TTWI@28211|Alphaproteobacteria,4BSQY@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	S	Protein of unknown function (DUF444)	yhbH	-	-	ko:K09786	-	-	-	-	ko00000	-	-	-	DUF444
k59_31357_1	580340.Tlie_0313	2.81e-31	129.0	COG4907@1|root,COG4907@2|Bacteria,3TA8F@508458|Synergistetes	508458|Synergistetes	S	membrane protein (DUF2207)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2207
k59_122355_1	1500897.JQNA01000001_gene6547	7.64e-97	317.0	COG0515@1|root,COG2203@1|root,COG3899@1|root,COG4191@1|root,COG0515@2|Bacteria,COG2203@2|Bacteria,COG3899@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2VICN@28216|Betaproteobacteria,1K3Q3@119060|Burkholderiaceae	28216|Betaproteobacteria	T	ATP-binding region ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GAF,GAF_2,HATPase_c,HisKA,PAS_3,PAS_9,Pkinase
k59_972_1	177437.HRM2_48570	3.69e-37	134.0	COG1397@1|root,COG1397@2|Bacteria,1Q98F@1224|Proteobacteria,42U7M@68525|delta/epsilon subdivisions,2WQUY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	ADP-ribosylglycohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	ADP_ribosyl_GH
k59_972_2	1304872.JAGC01000009_gene447	1.02e-33	129.0	COG0560@1|root,COG0560@2|Bacteria,1MWA3@1224|Proteobacteria,42NIR@68525|delta/epsilon subdivisions,2WIVQ@28221|Deltaproteobacteria,2M8ZT@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	TIGRFAM Phosphoserine phosphatase SerB	serB	-	3.1.3.3	ko:K01079	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R00582	RC00017	ko00000,ko00001,ko00002,ko01000,ko01009	-	-	-	ACT_6,HAD
k59_99602_1	933262.AXAM01000006_gene1837	2.1e-37	145.0	COG2114@1|root,COG2114@2|Bacteria,1MV1V@1224|Proteobacteria,42SUQ@68525|delta/epsilon subdivisions,2WPIY@28221|Deltaproteobacteria,2MPS7@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc,HAMP
k59_198155_1	1121405.dsmv_3317	8.67e-83	260.0	COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,42MEA@68525|delta/epsilon subdivisions,2WIW6@28221|Deltaproteobacteria,2MI74@213118|Desulfobacterales	28221|Deltaproteobacteria	KT	Sigma-54 interaction domain	-	-	2.1.1.80	ko:K00575	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	HTH_8,PAS_4,PAS_9,Sigma54_activat
k59_46515_1	589865.DaAHT2_1309	1.06e-60	212.0	COG4775@1|root,COG4775@2|Bacteria,1MU0D@1224|Proteobacteria,42MMA@68525|delta/epsilon subdivisions,2WIZB@28221|Deltaproteobacteria,2MIBK@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamA	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
k59_205832_1	1434929.X946_3446	2.62e-30	121.0	COG0741@1|root,COG0741@2|Bacteria,1MZ4X@1224|Proteobacteria,2VKFN@28216|Betaproteobacteria,1K0GR@119060|Burkholderiaceae	28216|Betaproteobacteria	M	transglycosylase	slt	-	3.2.1.17	ko:K01185	-	-	-	-	ko00000,ko01000	-	-	-	SLT
k59_975_1	290397.Adeh_1711	1.2e-14	79.7	COG1716@1|root,COG3829@1|root,COG1716@2|Bacteria,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,43C02@68525|delta/epsilon subdivisions,2X7AU@28221|Deltaproteobacteria,2YU9K@29|Myxococcales	28221|Deltaproteobacteria	KT	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	FHA,GAF,GAF_2,HTH_8,Sigma54_activat,Yop-YscD_cpl
k59_31365_1	1121405.dsmv_1665	4.29e-107	320.0	COG5557@1|root,COG5557@2|Bacteria,1PFX4@1224|Proteobacteria,42PIE@68525|delta/epsilon subdivisions,2WM3C@28221|Deltaproteobacteria,2MMPY@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Polysulphide reductase, NrfD	moz	-	-	ko:K00185	-	-	-	-	ko00000	5.A.3	-	-	DUF3341,NrfD
k59_228431_1	335543.Sfum_1911	1.35e-14	73.2	COG3028@1|root,COG3028@2|Bacteria,1MZ4R@1224|Proteobacteria,42WA0@68525|delta/epsilon subdivisions,2WRFU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Belongs to the UPF0307 family	-	-	-	ko:K09889	-	-	-	-	ko00000,ko03009	-	-	-	DUF615
k59_114716_1	880073.Calab_0319	1.15e-16	86.7	COG3604@1|root,COG3604@2|Bacteria	2|Bacteria	KT	transcription factor binding	nifA	-	-	ko:K02584,ko:K11914	ko02020,map02020	-	-	-	ko00000,ko00001,ko02044,ko03000	-	-	-	GAF,GAF_2,HTH_8,Sigma54_activat
k59_213265_1	56780.SYN_02231	1.96e-75	238.0	COG2843@1|root,COG2843@2|Bacteria,1P1MG@1224|Proteobacteria,42T4H@68525|delta/epsilon subdivisions,2X5J5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Bacterial capsule synthesis protein PGA_cap	-	-	6.3.2.10	ko:K01929,ko:K07282	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	PGA_cap
k59_198165_1	880072.Desac_0968	5.17e-60	196.0	COG1082@1|root,COG1082@2|Bacteria,1N8KJ@1224|Proteobacteria,42SR1@68525|delta/epsilon subdivisions,2WP5P@28221|Deltaproteobacteria,2MQKJ@213462|Syntrophobacterales	28221|Deltaproteobacteria	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
k59_46526_1	443152.MDG893_06660	1.24e-79	246.0	COG4239@1|root,COG4239@2|Bacteria,1MUM5@1224|Proteobacteria,1RNUH@1236|Gammaproteobacteria,464AH@72275|Alteromonadaceae	1236|Gammaproteobacteria	P	transport system, permease component	yejE	GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006857,GO:0008150,GO:0015833,GO:0015893,GO:0016020,GO:0035672,GO:0042221,GO:0042493,GO:0042884,GO:0042886,GO:0042891,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944	-	ko:K13895	ko02010,map02010	M00349	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.21,3.A.1.5.24	-	-	BPD_transp_1,OppC_N
k59_46526_2	1122212.AULO01000008_gene1321	7.49e-06	47.0	COG4174@1|root,COG4174@2|Bacteria,1MVKE@1224|Proteobacteria,1RMH8@1236|Gammaproteobacteria,1XH8Z@135619|Oceanospirillales	135619|Oceanospirillales	P	With YejAEF is involved in resistance to microcin C	oppB	-	-	ko:K13894	ko02010,map02010	M00349	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.21,3.A.1.5.24	-	-	BPD_transp_1
k59_39009_1	1121430.JMLG01000002_gene1079	1.88e-09	61.2	COG1024@1|root,COG1024@2|Bacteria,1TQ89@1239|Firmicutes,247RK@186801|Clostridia,26121@186807|Peptococcaceae	186801|Clostridia	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	4.2.1.17	ko:K01715	ko00650,ko01200,map00650,map01200	-	R03026	RC00831	ko00000,ko00001,ko01000	-	-	-	ECH_1
k59_190514_1	933262.AXAM01000001_gene333	4.18e-75	238.0	COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,42P5W@68525|delta/epsilon subdivisions,2WMA6@28221|Deltaproteobacteria,2MHP7@213118|Desulfobacterales	28221|Deltaproteobacteria	M	PFAM peptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
k59_175449_1	1128421.JAGA01000001_gene2057	1.88e-06	52.8	COG0745@1|root,COG0745@2|Bacteria,2NQA9@2323|unclassified Bacteria	2|Bacteria	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
k59_46529_1	1307761.L21SP2_2654	1.92e-23	100.0	COG3547@1|root,COG3547@2|Bacteria	2|Bacteria	L	Transposase (IS116 IS110 IS902 family)	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_236153_1	1121405.dsmv_0622	2.56e-91	274.0	COG0727@1|root,COG0727@2|Bacteria,1Q0JM@1224|Proteobacteria,42N6S@68525|delta/epsilon subdivisions,2WMTR@28221|Deltaproteobacteria,2MIXY@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Putative zinc- or iron-chelating domain	-	-	-	ko:K06940	-	-	-	-	ko00000	-	-	-	CxxCxxCC
k59_221042_1	667014.Thein_0249	8.25e-11	63.2	COG4177@1|root,COG4177@2|Bacteria,2GIF6@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	E	Branched-chain amino acid transport system / permease component	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
k59_221042_2	1121405.dsmv_0924	9.76e-83	255.0	COG0411@1|root,COG0411@2|Bacteria,1MUTY@1224|Proteobacteria,42M5G@68525|delta/epsilon subdivisions,2X5IV@28221|Deltaproteobacteria,2MPF2@213118|Desulfobacterales	28221|Deltaproteobacteria	E	branched-chain amino acid	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
k59_221042_3	880072.Desac_1842	1.52e-106	314.0	COG0410@1|root,COG0410@2|Bacteria,1MVVC@1224|Proteobacteria,42M9C@68525|delta/epsilon subdivisions,2WJ75@28221|Deltaproteobacteria,2MQVR@213462|Syntrophobacterales	28221|Deltaproteobacteria	E	ABC transporter	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
k59_183007_1	1278307.KB906976_gene1564	6.58e-62	212.0	COG1033@1|root,COG1033@2|Bacteria,1MUE1@1224|Proteobacteria,1RNWM@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Exporters of the RND superfamily	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
k59_31388_2	1336803.PHEL49_0972	2.07e-17	79.0	COG1595@1|root,COG1595@2|Bacteria,4NHNI@976|Bacteroidetes,1HY4K@117743|Flavobacteriia,3VV5J@52959|Polaribacter	976|Bacteroidetes	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
k59_137522_1	999141.GME_10031	3.94e-30	120.0	COG3650@1|root,COG3650@2|Bacteria,1N019@1224|Proteobacteria,1SBAD@1236|Gammaproteobacteria,1XQ93@135619|Oceanospirillales	135619|Oceanospirillales	S	Membrane-bound lysozyme-inhibitor of c-type lysozyme	-	-	-	-	-	-	-	-	-	-	-	-	MliC
k59_137522_2	1232437.KL662067_gene2490	2.7e-46	154.0	COG0252@1|root,COG0252@2|Bacteria,1RHAW@1224|Proteobacteria,42SNH@68525|delta/epsilon subdivisions,2WPQC@28221|Deltaproteobacteria,2MK6U@213118|Desulfobacterales	28221|Deltaproteobacteria	EJ	Asparaginase, N-terminal	aspG	-	3.5.1.1	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	-	R00485	RC00010,RC02798	ko00000,ko00001,ko01000	-	-	-	Asparaginase
k59_129991_1	756272.Plabr_1743	9.51e-13	65.9	COG3157@1|root,COG3157@2|Bacteria,2J0G0@203682|Planctomycetes	203682|Planctomycetes	S	TIGRFAM type VI secretion system effector, Hcp1 family	-	-	-	ko:K11903	ko02025,ko03070,map02025,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko02044	-	-	-	T6SS_HCP
k59_92037_1	933262.AXAM01000003_gene2862	1.7e-07	52.8	COG0795@1|root,COG0795@2|Bacteria,1MUF2@1224|Proteobacteria,42NYD@68525|delta/epsilon subdivisions,2WKHT@28221|Deltaproteobacteria,2MHU9@213118|Desulfobacterales	28221|Deltaproteobacteria	S	permease YjgP YjgQ family	lptF	-	-	ko:K07091	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
k59_92037_2	1167006.UWK_03507	9.89e-13	65.1	COG0764@1|root,COG0764@2|Bacteria,1RH2T@1224|Proteobacteria,42SCN@68525|delta/epsilon subdivisions,2WP3E@28221|Deltaproteobacteria,2MK6G@213118|Desulfobacterales	28221|Deltaproteobacteria	I	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs	fabZ	-	4.2.1.59	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121	RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FabA
k59_152812_1	556268.OFAG_02091	9.95e-09	57.0	COG3634@1|root,COG3634@2|Bacteria,1MUKD@1224|Proteobacteria,2VJ01@28216|Betaproteobacteria,473AQ@75682|Oxalobacteraceae	28216|Betaproteobacteria	O	Alkyl hydroperoxide reductase	ahpF	-	-	ko:K03387	-	-	-	-	ko00000,ko01000	-	-	-	Pyr_redox_2,Thioredoxin_3
k59_160393_1	760568.Desku_0815	6.22e-35	135.0	COG1053@1|root,COG1053@2|Bacteria,1TPAR@1239|Firmicutes,247SY@186801|Clostridia	186801|Clostridia	C	PFAM fumarate reductase succinate dehydrogenase flavoprotein	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_2,Succ_DH_flav_C
k59_145101_1	857087.Metme_4163	0.000213	46.6	COG0607@1|root,COG0607@2|Bacteria	2|Bacteria	P	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS	-	-	2.7.7.80,2.8.1.11	ko:K21147	ko04122,map04122	-	R07459,R07461	RC00043	ko00000,ko00001,ko01000	-	-	-	Rhodanese,Thioredoxin
k59_145101_2	316067.Geob_2508	3.79e-101	307.0	COG0709@1|root,COG0709@2|Bacteria,1MWFG@1224|Proteobacteria,42MC3@68525|delta/epsilon subdivisions,2WK3M@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	Synthesizes selenophosphate from selenide and ATP	selD	-	2.7.9.3	ko:K01008	ko00450,ko01100,map00450,map01100	-	R03595	RC00002,RC02878	ko00000,ko00001,ko01000,ko03016	-	-	-	AIRS,AIRS_C
k59_129996_1	96561.Dole_0595	1.13e-79	258.0	COG0768@1|root,COG0768@2|Bacteria,1MV8C@1224|Proteobacteria,42M1S@68525|delta/epsilon subdivisions,2WJ02@28221|Deltaproteobacteria,2MHV4@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Penicillin-binding Protein dimerisation domain	mrdA	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	iAF987.Gmet_0928	PBP_dimer,Transpeptidase
k59_152815_1	591019.Shell_0344	4.59e-12	66.2	COG0071@1|root,arCOG01833@2157|Archaea,2XQD6@28889|Crenarchaeota	28889|Crenarchaeota	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
k59_31393_1	498761.HM1_2373	1.71e-36	137.0	COG1058@1|root,COG1546@1|root,COG1058@2|Bacteria,COG1546@2|Bacteria,1TQ1N@1239|Firmicutes,249WC@186801|Clostridia	186801|Clostridia	S	Belongs to the CinA family	cinA	-	3.5.1.42	ko:K03742,ko:K03743	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA,MoCF_biosynth
k59_46548_1	1265505.ATUG01000001_gene3573	5.09e-98	306.0	COG0471@1|root,COG0471@2|Bacteria,1MU0K@1224|Proteobacteria,42MR7@68525|delta/epsilon subdivisions,2WIKA@28221|Deltaproteobacteria,2MIU8@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Citrate transporter	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS,Na_sulph_symp,TrkA_C
k59_28655_1	671143.DAMO_3067	5.08e-38	138.0	COG0702@1|root,COG0702@2|Bacteria	2|Bacteria	GM	epimerase	-	-	1.6.5.3,1.6.99.3	ko:K00329,ko:K00356	ko00190,map00190	-	R11945	RC00061	ko00000,ko00001,ko01000	-	-	-	Epimerase,NAD_binding_10
k59_28655_2	1304275.C41B8_04656	9.37e-59	199.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,1T1II@1236|Gammaproteobacteria	1236|Gammaproteobacteria	IQ	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II	JD73_00810	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C_2,PP-binding
k59_43919_1	289376.THEYE_A0933	1.79e-68	216.0	COG0329@1|root,COG0329@2|Bacteria,3J0CF@40117|Nitrospirae	40117|Nitrospirae	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
k59_112829_1	292564.Cyagr_2825	3.09e-12	71.6	COG0457@1|root,COG2114@1|root,COG3899@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG3899@2|Bacteria,1G4G4@1117|Cyanobacteria	1117|Cyanobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Guanylate_cyc
k59_218581_1	667014.Thein_0095	4.14e-48	171.0	COG4231@1|root,COG4231@2|Bacteria,2GH8H@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	C	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain	-	-	1.2.7.8	ko:K00179	-	-	-	-	br01601,ko00000,ko01000	-	-	-	POR_N,TPP_enzyme_C
k59_234434_1	1173020.Cha6605_0123	1.76e-18	90.9	COG3541@1|root,COG3541@2|Bacteria,1G2ZU@1117|Cyanobacteria	1117|Cyanobacteria	S	Nucleotidyltransferase	-	-	-	ko:K07074	-	-	-	-	ko00000	-	-	-	Nuc-transf
k59_189011_1	96561.Dole_2495	4.83e-78	248.0	COG1220@1|root,COG1220@2|Bacteria,1MVK9@1224|Proteobacteria,42M48@68525|delta/epsilon subdivisions,2WISV@28221|Deltaproteobacteria,2MIBH@213118|Desulfobacterales	28221|Deltaproteobacteria	O	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis	hslU	-	-	ko:K03667	-	-	-	-	ko00000,ko03110	-	-	-	AAA_2,ClpB_D2-small
k59_180478_2	1232437.KL662032_gene2513	6.14e-19	79.7	2EQSX@1|root,33ICQ@2|Bacteria,1NMT6@1224|Proteobacteria,42XF7@68525|delta/epsilon subdivisions,2WT05@28221|Deltaproteobacteria,2MPAZ@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Putative transposon-encoded protein (DUF2080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2080
k59_218585_1	933262.AXAM01000034_gene1557	3.91e-154	448.0	COG0465@1|root,COG0465@2|Bacteria,1MU6J@1224|Proteobacteria,42M4Z@68525|delta/epsilon subdivisions,2WJ0D@28221|Deltaproteobacteria,2MIPH@213118|Desulfobacterales	28221|Deltaproteobacteria	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
k59_226189_2	5786.XP_003291681.1	1.91e-06	52.4	28Q01@1|root,2QWNR@2759|Eukaryota,3X9TN@554915|Amoebozoa	554915|Amoebozoa	S	NYN domain	-	-	-	-	-	-	-	-	-	-	-	-	AMPK1_CBM,NYN,OHA
k59_127966_2	575788.VS_II1098	1.75e-15	82.0	COG4104@1|root,COG4104@2|Bacteria	2|Bacteria	T	PAAR repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	PAAR_motif
k59_189014_1	1121405.dsmv_3267	2.4e-91	283.0	COG1530@1|root,COG1530@2|Bacteria,1MV65@1224|Proteobacteria,42M5E@68525|delta/epsilon subdivisions,2WIV6@28221|Deltaproteobacteria,2MISJ@213118|Desulfobacterales	28221|Deltaproteobacteria	J	ribonuclease Rne Rng family	cafA	-	3.1.26.12	ko:K08300,ko:K08301	ko03018,map03018	M00394	-	-	ko00000,ko00001,ko00002,ko01000,ko03009,ko03019	-	-	-	RNase_E_G,S1
k59_241235_1	1165841.SULAR_09619	1.62e-146	415.0	COG2020@1|root,COG2020@2|Bacteria,1R7G6@1224|Proteobacteria,42TT9@68525|delta/epsilon subdivisions	1224|Proteobacteria	O	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	ICMT,PEMT
k59_127973_1	933262.AXAM01000093_gene1593	4.66e-50	170.0	COG3385@1|root,COG3385@2|Bacteria,1REZ3@1224|Proteobacteria,42RPA@68525|delta/epsilon subdivisions,2WNFF@28221|Deltaproteobacteria,2MPI9@213118|Desulfobacterales	28221|Deltaproteobacteria	L	PFAM transposase, IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
k59_43933_1	455436.DS989813_gene1031	1.26e-23	105.0	COG1472@1|root,COG1472@2|Bacteria,1MVAJ@1224|Proteobacteria,1RMQF@1236|Gammaproteobacteria,465G4@72275|Alteromonadaceae	1236|Gammaproteobacteria	G	Beta-N-acetylhexosaminidase	ybbD	-	3.2.1.52	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	M00628	R00022,R05963,R07809,R07810,R10831	RC00049	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyco_hydro_3,Glyco_hydro_3_C
k59_43933_2	335543.Sfum_0531	5.5e-55	186.0	COG1208@1|root,COG1208@2|Bacteria,1PDPD@1224|Proteobacteria,43A25@68525|delta/epsilon subdivisions,2X1ZV@28221|Deltaproteobacteria,2MRR3@213462|Syntrophobacterales	28221|Deltaproteobacteria	JM	Nucleotidyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transferase
k59_135875_1	397291.C804_05817	1.98e-18	93.6	COG5518@1|root,COG5518@2|Bacteria,1TT5R@1239|Firmicutes,24XUM@186801|Clostridia	186801|Clostridia	S	Bacteriophage capsid portal protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_211609_1	1121405.dsmv_1982	1.08e-13	71.2	COG2876@1|root,COG2876@2|Bacteria,1QVAD@1224|Proteobacteria,42MU4@68525|delta/epsilon subdivisions,2WJ8Y@28221|Deltaproteobacteria,2MJBB@213118|Desulfobacterales	28221|Deltaproteobacteria	E	PFAM DAHP synthetase I	-	-	2.5.1.54,5.4.99.5	ko:K03856,ko:K04516	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022,M00024,M00025	R01715,R01826	RC00435,RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	CM_2,DAHP_synth_1
k59_97472_1	665942.HMPREF1022_00032	9.6e-06	52.0	COG0574@1|root,COG3848@1|root,COG0574@2|Bacteria,COG3848@2|Bacteria,1MU0R@1224|Proteobacteria,42MW3@68525|delta/epsilon subdivisions,2WIXV@28221|Deltaproteobacteria,2M800@213115|Desulfovibrionales	28221|Deltaproteobacteria	G	PFAM Pyruvate phosphate dikinase, PEP	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PPDK_N
k59_97472_2	1121441.AUCX01000021_gene714	0.000212	46.2	2AFUA@1|root,315WQ@2|Bacteria,1NHGB@1224|Proteobacteria,42TSA@68525|delta/epsilon subdivisions,2WQKD@28221|Deltaproteobacteria,2M9ZQ@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Putative transmembrane protein (Alph_Pro_TM)	-	-	-	-	-	-	-	-	-	-	-	-	Alph_Pro_TM
k59_143442_2	644282.Deba_1846	7.76e-28	103.0	COG0776@1|root,COG0776@2|Bacteria,1RH5Z@1224|Proteobacteria,42W2F@68525|delta/epsilon subdivisions,2WRUM@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control	ihfA	-	-	ko:K04764	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
k59_43939_1	439235.Dalk_3669	8.78e-96	290.0	COG0683@1|root,COG0683@2|Bacteria,1MWJ1@1224|Proteobacteria,42MSJ@68525|delta/epsilon subdivisions,2WKHJ@28221|Deltaproteobacteria,2MITB@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Receptor family ligand binding region	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
k59_43939_2	335543.Sfum_1404	4.97e-20	88.6	COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,42MQS@68525|delta/epsilon subdivisions,2WINP@28221|Deltaproteobacteria,2MR0I@213462|Syntrophobacterales	28221|Deltaproteobacteria	I	PFAM Enoyl-CoA hydratase isomerase	-	-	1.1.1.35,4.2.1.17,5.1.2.3,5.3.3.8	ko:K01782,ko:K01825	ko00071,ko00280,ko00281,ko00310,ko00362,ko00380,ko00410,ko00640,ko00650,ko00903,ko00930,ko01040,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00071,map00280,map00281,map00310,map00362,map00380,map00410,map00640,map00650,map00903,map00930,map01040,map01100,map01110,map01120,map01130,map01200,map01212	M00032,M00087	R01975,R03026,R03045,R03276,R04137,R04170,R04203,R04204,R04224,R04737,R04738,R04739,R04740,R04741,R04744,R04745,R04746,R04748,R04749,R04756,R05066,R05305,R06411,R06412,R06941,R06942,R07935,R07951,R08093,R08094	RC00029,RC00099,RC00117,RC00241,RC00525,RC00831,RC00834,RC00896,RC01078,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	3HCDH,3HCDH_N,ECH_1
k59_143445_1	641491.DND132_1390	1.58e-19	88.2	COG1035@1|root,COG1150@1|root,COG1035@2|Bacteria,COG1150@2|Bacteria,1R4GN@1224|Proteobacteria,42P9J@68525|delta/epsilon subdivisions,2WJ9S@28221|Deltaproteobacteria,2MGKM@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein	-	-	1.17.1.9	ko:K00125	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Fer4,Fer4_17,FrhB_FdhB_C
k59_143445_2	335543.Sfum_0823	1.48e-55	175.0	COG1908@1|root,COG1908@2|Bacteria,1RCZY@1224|Proteobacteria,42RK0@68525|delta/epsilon subdivisions,2WNZZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM methyl-viologen-reducing hydrogenase delta subunit	-	-	1.8.98.5,1.8.98.6	ko:K14127	ko00680,map00680	-	R00019,R11943,R11944	RC00011	ko00000,ko00001,ko01000	-	-	-	FlpD
k59_37086_1	1009370.ALO_09899	2.49e-67	230.0	COG0068@1|root,COG0068@2|Bacteria,1TQM7@1239|Firmicutes,4H3B6@909932|Negativicutes	909932|Negativicutes	O	Belongs to the carbamoyltransferase HypF family	hypF	-	-	ko:K04656	-	-	-	-	ko00000	-	-	-	Acylphosphatase,Sua5_yciO_yrdC,zf-HYPF
k59_66808_2	1121405.dsmv_1912	2.8e-22	94.7	COG2086@1|root,COG2086@2|Bacteria,1MVH6@1224|Proteobacteria,42RCI@68525|delta/epsilon subdivisions,2WMYC@28221|Deltaproteobacteria,2MJI4@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Electron transfer flavoprotein domain	etfB	-	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
k59_21419_1	933262.AXAM01000020_gene23	9.04e-65	214.0	COG0342@1|root,COG0342@2|Bacteria,1MV5U@1224|Proteobacteria,42M6V@68525|delta/epsilon subdivisions,2WJCI@28221|Deltaproteobacteria,2MHS8@213118|Desulfobacterales	28221|Deltaproteobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
k59_165298_2	593750.Metfor_2049	3.56e-38	136.0	COG4294@1|root,arCOG01898@2157|Archaea,2XVT2@28890|Euryarchaeota	28890|Euryarchaeota	L	UV-endonuclease UvdE	uvsE	-	-	ko:K13281	-	-	-	-	ko00000,ko01000	-	-	-	UvdE
k59_234451_1	1121918.ARWE01000001_gene1120	2.79e-77	238.0	COG1136@1|root,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,42PYJ@68525|delta/epsilon subdivisions,2WKHY@28221|Deltaproteobacteria,43SDA@69541|Desulfuromonadales	28221|Deltaproteobacteria	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
k59_51635_1	1190606.AJYG01000074_gene170	4.9e-91	283.0	COG1178@1|root,COG1178@2|Bacteria,1MXZZ@1224|Proteobacteria,1RY3W@1236|Gammaproteobacteria,1XTGS@135623|Vibrionales	135623|Vibrionales	P	ABC-type Fe3 transport system, permease component	-	-	-	ko:K02011	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	BPD_transp_1
k59_37094_1	582515.KR51_00034820	2.78e-07	55.1	COG2159@1|root,COG2159@2|Bacteria,1G4XF@1117|Cyanobacteria	1117|Cyanobacteria	S	Transposase DDE domain group 1	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_4
k59_66814_1	1430331.EP10_10790	3.67e-31	125.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4HA3S@91061|Bacilli,1WEWQ@129337|Geobacillus	91061|Bacilli	V	ABC transporter transmembrane region	yfiC3	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
k59_173314_1	1121413.JMKT01000008_gene1110	1.2e-62	195.0	COG4852@1|root,COG4852@2|Bacteria,1MZHP@1224|Proteobacteria,42TD7@68525|delta/epsilon subdivisions,2WPIH@28221|Deltaproteobacteria,2MF5C@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Predicted membrane protein (DUF2177)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2177
k59_165301_1	933262.AXAM01000107_gene1504	2.57e-86	276.0	COG0493@1|root,COG2878@1|root,COG0493@2|Bacteria,COG2878@2|Bacteria,1NZIR@1224|Proteobacteria,42MPF@68525|delta/epsilon subdivisions,2X5BJ@28221|Deltaproteobacteria,2MISB@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Putative Fe-S cluster	-	-	-	-	-	-	-	-	-	-	-	-	FeS,Fer4,Fer4_20,Fer4_9,Pyr_redox_2
k59_195511_1	225849.swp_4060	3.33e-85	264.0	COG2829@1|root,COG2829@2|Bacteria,1PC8I@1224|Proteobacteria,1RMJH@1236|Gammaproteobacteria,2QA4P@267890|Shewanellaceae	1236|Gammaproteobacteria	M	PFAM phospholipase A1	pldA	-	3.1.1.32,3.1.1.4	ko:K01058	ko00564,ko00565,ko00590,ko00591,ko00592,ko01100,ko01110,map00564,map00565,map00590,map00591,map00592,map01100,map01110	-	R01315,R01316,R01317,R02053,R02054,R04034,R07064,R07379,R07387,R07859,R07860	RC00020,RC00037,RC00041,RC00094	ko00000,ko00001,ko01000	-	-	-	PLA1
k59_82617_1	335543.Sfum_1741	5.21e-61	212.0	COG1074@1|root,COG1074@2|Bacteria,1MUTF@1224|Proteobacteria,42NKH@68525|delta/epsilon subdivisions,2WJTY@28221|Deltaproteobacteria,2MRGC@213462|Syntrophobacterales	28221|Deltaproteobacteria	L	Belongs to the helicase family. UvrD subfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
k59_66824_1	1232410.KI421418_gene2263	3.71e-47	158.0	COG0528@1|root,COG0528@2|Bacteria,1MV3N@1224|Proteobacteria,42M3X@68525|delta/epsilon subdivisions,2WJDF@28221|Deltaproteobacteria,43SW0@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
k59_189033_1	879212.DespoDRAFT_01976	1.02e-105	316.0	COG0701@1|root,COG0701@2|Bacteria,1MUN8@1224|Proteobacteria,42N6E@68525|delta/epsilon subdivisions,2WJXG@28221|Deltaproteobacteria,2MJ1N@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Predicted permease	-	-	-	ko:K07089	-	-	-	-	ko00000	-	-	-	ArsP_1
k59_158302_1	526222.Desal_3678	6.78e-30	120.0	COG2204@1|root,COG2206@1|root,COG2204@2|Bacteria,COG2206@2|Bacteria,1RAQS@1224|Proteobacteria,42YJ6@68525|delta/epsilon subdivisions,2WURA@28221|Deltaproteobacteria,2MH8V@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	metal-dependent phosphohydrolase HD region	-	-	-	-	-	-	-	-	-	-	-	-	HD,PAS_4,PAS_9,Response_reg
k59_66827_1	62928.azo2691	4.63e-09	62.4	COG2199@1|root,COG3706@2|Bacteria,1MXAW@1224|Proteobacteria,2VK79@28216|Betaproteobacteria,2KUEF@206389|Rhodocyclales	206389|Rhodocyclales	T	GGDEF domain	-	-	2.7.7.65	ko:K13590	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000	-	-	-	GGDEF
k59_203772_1	1043493.BBLU01000005_gene1971	1.6e-15	75.9	COG0071@1|root,COG0071@2|Bacteria,2IHVJ@201174|Actinobacteria	201174|Actinobacteria	O	Belongs to the small heat shock protein (HSP20) family	hsp18	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
k59_43973_1	439235.Dalk_3023	4.17e-88	279.0	COG1038@1|root,COG1038@2|Bacteria,1R7P1@1224|Proteobacteria,42PQ3@68525|delta/epsilon subdivisions,2WJK5@28221|Deltaproteobacteria,2MJRR@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Conserved carboxylase domain	-	-	6.4.1.1	ko:K01958	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	M00173	R00344	RC00040,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_lipoyl,HMGL-like,PYC_OADA
k59_66829_1	634499.EpC_29040	5.14e-39	135.0	COG1396@1|root,COG1396@2|Bacteria,1RF9G@1224|Proteobacteria,1S5F5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
k59_158305_1	864051.BurJ1DRAFT_0734	3.16e-37	131.0	COG2050@1|root,COG2050@2|Bacteria,1N5HF@1224|Proteobacteria,2VQ8W@28216|Betaproteobacteria,1KM7Y@119065|unclassified Burkholderiales	28216|Betaproteobacteria	Q	Thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
k59_158305_2	518637.EUBIFOR_02514	3.55e-12	68.9	COG1307@1|root,COG1307@2|Bacteria,1TRM7@1239|Firmicutes,3VQ9D@526524|Erysipelotrichia	526524|Erysipelotrichia	S	EDD domain protein, DegV family	-	-	-	-	-	-	-	-	-	-	-	-	DegV
k59_211649_1	1232410.KI421422_gene2071	4.21e-78	256.0	COG0542@1|root,COG0542@2|Bacteria,1MURH@1224|Proteobacteria,42M9S@68525|delta/epsilon subdivisions,2WJSZ@28221|Deltaproteobacteria,43S73@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
k59_37580_1	573370.DMR_07000	2.36e-16	78.2	COG4244@1|root,COG4892@1|root,COG4244@2|Bacteria,COG4892@2|Bacteria,1N3DP@1224|Proteobacteria,42U1X@68525|delta/epsilon subdivisions,2WQFI@28221|Deltaproteobacteria,2M8Q3@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	PFAM cytochrome	-	-	-	-	-	-	-	-	-	-	-	-	CopD,Cyt-b5
k59_44502_1	985665.HPL003_10025	3.04e-43	157.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,1TNZE@1239|Firmicutes,4HBZC@91061|Bacilli,26SRH@186822|Paenibacillaceae	91061|Bacilli	G	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	Carb_kinase,YjeF_N
k59_181006_1	207559.Dde_0310	7.13e-76	245.0	COG0038@1|root,COG0517@1|root,COG0038@2|Bacteria,COG0517@2|Bacteria,1MV4K@1224|Proteobacteria,42PJQ@68525|delta/epsilon subdivisions,2WKR4@28221|Deltaproteobacteria,2M7SH@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	Voltage gated chloride channel	-	-	-	ko:K03281	-	-	-	-	ko00000	2.A.49	-	iAF987.Gmet_3470	CBS,Voltage_CLC
k59_219127_1	309800.C498_02055	0.000792	47.4	arCOG05978@1|root,arCOG05978@2157|Archaea,2XU7Y@28890|Euryarchaeota,23SST@183963|Halobacteria	183963|Halobacteria	S	Fibronectin type III domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_226751_1	1121430.JMLG01000021_gene1382	1.04e-22	94.7	COG0169@1|root,COG0169@2|Bacteria,1TQRY@1239|Firmicutes,2497S@186801|Clostridia,2619R@186807|Peptococcaceae	186801|Clostridia	E	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	aroE	-	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	-	Shikimate_DH,Shikimate_dh_N
k59_226751_2	13333.ERN16858	5.48e-14	75.9	COG0169@1|root,KOG0692@2759|Eukaryota,37I1M@33090|Viridiplantae,3GDN1@35493|Streptophyta	35493|Streptophyta	E	Bifunctional 3-dehydroquinate dehydratase shikimate dehydrogenase	-	-	1.1.1.25,4.2.1.10	ko:K13832	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413,R03084	RC00206,RC00848	ko00000,ko00001,ko00002,ko01000	-	-	-	DHquinase_I,Shikimate_DH,Shikimate_dh_N
k59_37586_1	263358.VAB18032_11710	1.18e-07	59.7	COG1233@1|root,COG1233@2|Bacteria,2GMUC@201174|Actinobacteria,4DB0E@85008|Micromonosporales	201174|Actinobacteria	Q	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase,NAD_binding_8
k59_150619_1	1121405.dsmv_0457	1.52e-78	253.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,42M51@68525|delta/epsilon subdivisions,2WIPP@28221|Deltaproteobacteria,2MHPE@213118|Desulfobacterales	28221|Deltaproteobacteria	NU	type II secretion system protein E	gspE	-	-	ko:K02454	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSE,T2SSE_N
k59_113479_1	706587.Desti_2333	2.24e-48	163.0	COG0546@1|root,COG0546@2|Bacteria,1P1EG@1224|Proteobacteria,431YQ@68525|delta/epsilon subdivisions,2WWM2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	HAD-hyrolase-like	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
k59_60480_1	1499967.BAYZ01000054_gene4804	4.18e-55	179.0	COG0647@1|root,COG0647@2|Bacteria,2NPEG@2323|unclassified Bacteria	2|Bacteria	G	Haloacid dehalogenase-like hydrolase	nagD	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006220,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008252,GO:0008253,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009125,GO:0009129,GO:0009131,GO:0009158,GO:0009161,GO:0009164,GO:0009166,GO:0009173,GO:0009175,GO:0009218,GO:0009222,GO:0009259,GO:0009261,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042454,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046049,GO:0046050,GO:0046131,GO:0046133,GO:0046135,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0055086,GO:0071704,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658	-	ko:K02566	-	-	-	-	ko00000	-	-	-	Hydrolase_6,Hydrolase_like
k59_196044_1	909663.KI867150_gene900	6.61e-24	110.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42PZ5@68525|delta/epsilon subdivisions,2WKWB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase HAMP	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
k59_75193_1	755732.Fluta_3961	1.87e-184	535.0	COG3666@1|root,COG3666@2|Bacteria,4NEDD@976|Bacteroidetes,1HYXT@117743|Flavobacteriia,2PC3Q@246874|Cryomorphaceae	976|Bacteroidetes	L	COGs COG3666 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_6,DUF772
k59_226767_2	1237149.C900_04343	1.94e-50	177.0	COG4770@1|root,COG4770@2|Bacteria,4NM1W@976|Bacteroidetes,47M7U@768503|Cytophagia	976|Bacteroidetes	I	PFAM Carbamoyl-phosphate synthase L chain, ATP binding	-	-	6.3.4.14,6.4.1.2,6.4.1.3	ko:K01961,ko:K01965	ko00061,ko00280,ko00620,ko00630,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00373,M00376,M00741	R00742,R01859,R04385	RC00040,RC00097,RC00253,RC00367,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
k59_67379_1	439235.Dalk_2669	1.22e-63	219.0	COG1924@1|root,COG3580@1|root,COG3581@1|root,COG1924@2|Bacteria,COG3580@2|Bacteria,COG3581@2|Bacteria,1PKG6@1224|Proteobacteria,42MY4@68525|delta/epsilon subdivisions,2WJFI@28221|Deltaproteobacteria,2MIP0@213118|Desulfobacterales	28221|Deltaproteobacteria	I	BadF BadG BcrA BcrD	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG,DUF2229
k59_164502_1	338963.Pcar_1181	2.49e-75	257.0	COG2114@1|root,COG3899@1|root,COG2114@2|Bacteria,COG3899@2|Bacteria,1PFBZ@1224|Proteobacteria,439XJ@68525|delta/epsilon subdivisions,2X1UU@28221|Deltaproteobacteria,43VBR@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc
k59_59132_1	883080.HMPREF9697_00862	7.19e-23	96.7	COG3090@1|root,COG3090@2|Bacteria,1MVKS@1224|Proteobacteria,2U08K@28211|Alphaproteobacteria,3JQRU@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	G	Tripartite ATP-independent periplasmic transporters, DctQ component	MA20_30165	-	-	-	-	-	-	-	-	-	-	-	DctQ
k59_194685_2	439235.Dalk_3626	3.38e-81	254.0	COG0055@1|root,COG0055@2|Bacteria,1MUFU@1224|Proteobacteria,42KZA@68525|delta/epsilon subdivisions,2WJ1V@28221|Deltaproteobacteria,2MI99@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
k59_217844_1	525897.Dbac_3016	2.1e-24	95.5	COG3030@1|root,COG3030@2|Bacteria,1MZJJ@1224|Proteobacteria,42VMT@68525|delta/epsilon subdivisions,2WPFB@28221|Deltaproteobacteria,2MCEP@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	PFAM FxsA cytoplasmic membrane protein	fsxA	-	-	ko:K07113	-	-	-	-	ko00000	-	-	-	FxsA
k59_50847_1	794903.OPIT5_05135	9.05e-68	233.0	COG0178@1|root,COG0178@2|Bacteria,46SAF@74201|Verrucomicrobia,3K79V@414999|Opitutae	414999|Opitutae	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	-	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
k59_188152_1	867903.ThesuDRAFT_02360	5.23e-72	244.0	COG0178@1|root,COG0178@2|Bacteria,1TPIJ@1239|Firmicutes,2485F@186801|Clostridia,3WCFP@538999|Clostridiales incertae sedis	186801|Clostridia	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
k59_240376_1	1121405.dsmv_2186	3.38e-30	120.0	COG1219@1|root,COG1219@2|Bacteria,1MWIZ@1224|Proteobacteria,42N1Z@68525|delta/epsilon subdivisions,2WJUS@28221|Deltaproteobacteria,2MHMD@213118|Desulfobacterales	28221|Deltaproteobacteria	O	Belongs to the ClpX chaperone family	-	-	-	-	-	-	-	-	-	-	-	-	AAA_2,ClpB_D2-small
k59_240376_2	525146.Ddes_0289	2.93e-45	156.0	COG0535@1|root,COG0535@2|Bacteria,1MUQP@1224|Proteobacteria,42N9E@68525|delta/epsilon subdivisions,2WJAX@28221|Deltaproteobacteria,2M7YX@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	SMART Elongator protein 3 MiaB NifB	-	-	-	ko:K22226	-	-	-	-	ko00000	-	-	-	Fer4_12,Radical_SAM,SPASM
k59_217848_1	880072.Desac_1111	1.18e-86	273.0	COG0443@1|root,COG0443@2|Bacteria,1MVEN@1224|Proteobacteria,42M64@68525|delta/epsilon subdivisions,2WIWS@28221|Deltaproteobacteria,2MR7D@213462|Syntrophobacterales	28221|Deltaproteobacteria	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
k59_194690_1	502025.Hoch_5903	2.75e-50	170.0	COG0468@1|root,COG0468@2|Bacteria,1MU3C@1224|Proteobacteria,42M69@68525|delta/epsilon subdivisions,2WIYC@28221|Deltaproteobacteria,2YTSX@29|Myxococcales	28221|Deltaproteobacteria	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	-	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
k59_217849_1	102232.GLO73106DRAFT_00018930	6.55e-41	147.0	COG1752@1|root,COG1752@2|Bacteria,1G2F8@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM Patatin	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
k59_111966_2	1121085.AUCI01000055_gene2480	4.48e-97	306.0	COG4584@1|root,COG4584@2|Bacteria,1TR5X@1239|Firmicutes,4H9QJ@91061|Bacilli,1ZD2W@1386|Bacillus	91061|Bacilli	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	HTH_38,HTH_7,rve
k59_81667_1	96561.Dole_1174	5.56e-59	195.0	COG1968@1|root,COG1968@2|Bacteria,1MX02@1224|Proteobacteria,42N67@68525|delta/epsilon subdivisions,2WPKC@28221|Deltaproteobacteria,2MJE6@213118|Desulfobacterales	28221|Deltaproteobacteria	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
k59_97161_1	102125.Xen7305DRAFT_00039590	1.51e-52	168.0	2ERVI@1|root,33JEQ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_97161_2	269797.Mbar_A3080	2.96e-60	197.0	COG0641@1|root,arCOG00945@2157|Archaea,2Y0F7@28890|Euryarchaeota,2NAGD@224756|Methanomicrobia	224756|Methanomicrobia	K	SEC-C motif	-	-	-	ko:K06871	-	-	-	-	ko00000	-	-	-	Fer4_12,Radical_SAM,SEC-C,SPASM
k59_119581_1	933262.AXAM01000048_gene2587	1.29e-64	206.0	COG0020@1|root,COG0020@2|Bacteria,1MVP1@1224|Proteobacteria,42PTV@68525|delta/epsilon subdivisions,2WMWK@28221|Deltaproteobacteria,2MIZD@213118|Desulfobacterales	28221|Deltaproteobacteria	I	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	uppS	GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
k59_14324_1	1265505.ATUG01000002_gene1932	2.91e-148	441.0	COG1882@1|root,COG1882@2|Bacteria,1MWBF@1224|Proteobacteria,42M5J@68525|delta/epsilon subdivisions,2WJAK@28221|Deltaproteobacteria,2MI4X@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM formate C-acetyltransferase glycine radical	-	-	2.3.1.54,4.1.99.11	ko:K00656,ko:K07540	ko00620,ko00623,ko00640,ko00650,ko01100,ko01120,ko01220,map00620,map00623,map00640,map00650,map01100,map01120,map01220	M00418	R00212,R05598,R06987	RC00004,RC01181,RC01433,RC01434,RC02742,RC02833	ko00000,ko00001,ko00002,ko01000	-	-	-	Gly_radical,PFL-like
k59_82233_1	1265505.ATUG01000002_gene2618	5.72e-56	184.0	COG0301@1|root,COG0301@2|Bacteria,1N1R1@1224|Proteobacteria,42MQ9@68525|delta/epsilon subdivisions,2WJPN@28221|Deltaproteobacteria,2MICH@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Thiamine biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF814,ThiI
k59_43611_1	596151.DesfrDRAFT_3125	1.57e-83	259.0	COG4671@1|root,COG4671@2|Bacteria,1N1PQ@1224|Proteobacteria,42MDW@68525|delta/epsilon subdivisions,2WKQK@28221|Deltaproteobacteria,2M92X@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	PFAM Glycosyltransferase 28	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tran_28_C
k59_97176_2	1121413.JMKT01000009_gene2035	4.13e-35	129.0	COG0558@1|root,COG0558@2|Bacteria,1MZ8B@1224|Proteobacteria,42TIF@68525|delta/epsilon subdivisions,2WQC4@28221|Deltaproteobacteria,2MBN3@213115|Desulfovibrionales	28221|Deltaproteobacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pgsA-2	-	2.7.8.41	ko:K08744	ko00564,ko01100,map00564,map01100	-	R02030	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
k59_143055_1	439235.Dalk_0544	3.46e-45	166.0	COG0642@1|root,COG0745@1|root,COG0784@1|root,COG2198@1|root,COG0745@2|Bacteria,COG0784@2|Bacteria,COG2198@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,42M0Y@68525|delta/epsilon subdivisions,2WJCX@28221|Deltaproteobacteria,2MPM4@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Histidine Phosphotransfer domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF3365,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_9,PilJ,Response_reg,dCache_1
k59_195203_1	552811.Dehly_1358	1.4e-15	80.5	COG1477@1|root,COG1477@2|Bacteria,2G6WH@200795|Chloroflexi,34CQG@301297|Dehalococcoidia	301297|Dehalococcoidia	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	-	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
k59_203480_1	439235.Dalk_0340	4.19e-63	208.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,2MIB8@213118|Desulfobacterales	28221|Deltaproteobacteria	T	response regulator receiver	-	-	-	ko:K02481,ko:K07713	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
k59_66520_1	118005.AWNK01000009_gene198	4.04e-31	129.0	COG0642@1|root,COG0715@1|root,COG0834@1|root,COG0642@2|Bacteria,COG0715@2|Bacteria,COG0834@2|Bacteria	2|Bacteria	ET	amino acid transport	-	-	2.7.13.3	ko:K07679,ko:K20974	ko02020,ko02025,ko05133,map02020,map02025,map05133	M00477,M00820	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	GGDEF,HATPase_c,HisKA,Hpt,NMT1,PAS_3,PAS_4,PAS_8,PAS_9,Peripla_BP_4,Response_reg,SBP_bac_3
k59_97179_1	1232437.KL661999_gene4697	1.29e-25	101.0	COG2057@1|root,COG2057@2|Bacteria,1MY3S@1224|Proteobacteria,42R4B@68525|delta/epsilon subdivisions,2WMZN@28221|Deltaproteobacteria,2MHNA@213118|Desulfobacterales	28221|Deltaproteobacteria	I	PFAM Coenzyme A transferase	-	-	2.8.3.12	ko:K01040	ko00643,ko00650,ko01120,map00643,map00650,map01120	-	R04000,R05509	RC00012,RC00131,RC00137	ko00000,ko00001,ko01000	-	-	-	CoA_trans
k59_97179_2	177437.HRM2_38690	8.49e-89	271.0	COG1788@1|root,COG1788@2|Bacteria,1NGS5@1224|Proteobacteria,42Q6C@68525|delta/epsilon subdivisions,2WMD6@28221|Deltaproteobacteria,2MHY6@213118|Desulfobacterales	28221|Deltaproteobacteria	I	Coenzyme A transferase	-	-	2.8.3.12	ko:K01039	ko00643,ko00650,ko01120,map00643,map00650,map01120	-	R04000,R05509	RC00012,RC00131,RC00137	ko00000,ko00001,ko01000	-	-	-	CoA_trans
k59_180190_2	933262.AXAM01000013_gene1326	6.6e-36	125.0	COG0789@1|root,COG0789@2|Bacteria,1RGYB@1224|Proteobacteria,42V1F@68525|delta/epsilon subdivisions,2WR79@28221|Deltaproteobacteria,2MKW6@213118|Desulfobacterales	28221|Deltaproteobacteria	K	Regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
k59_59682_1	1163730.FFONT_0759	5.21e-21	88.2	COG1056@1|root,arCOG00972@2157|Archaea,2XQI1@28889|Crenarchaeota	28889|Crenarchaeota	F	nicotinamide-nucleotide adenylyltransferase	nadM	-	2.7.7.1	ko:K00952	ko00760,ko01100,map00760,map01100	-	R00137,R03005	RC00002	ko00000,ko00001,ko01000	-	-	-	CTP_transf_like
k59_225872_1	324602.Caur_3745	9.18e-112	339.0	COG3385@1|root,COG3385@2|Bacteria	2|Bacteria	L	transposase activity	-	-	-	-	-	-	-	-	-	-	-	-	DDE_5
k59_51366_1	879212.DespoDRAFT_03765	3.89e-85	258.0	COG2022@1|root,COG2022@2|Bacteria,1N0N5@1224|Proteobacteria,42MNC@68525|delta/epsilon subdivisions,2WIUI@28221|Deltaproteobacteria,2MIPN@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S	thiG	GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.8.1.10	ko:K03149	ko00730,ko01100,map00730,map01100	-	R10247	RC03096,RC03097,RC03461	ko00000,ko00001,ko01000	-	-	-	ThiG
k59_211268_1	1382306.JNIM01000001_gene2906	3.4e-158	455.0	COG2224@1|root,COG2224@2|Bacteria,2G61J@200795|Chloroflexi	200795|Chloroflexi	C	PFAM isocitrate lyase and phosphorylmutase	-	-	4.1.3.1	ko:K01637	ko00630,ko01100,ko01110,ko01120,ko01200,map00630,map01100,map01110,map01120,map01200	M00012	R00479	RC00311,RC00313	ko00000,ko00001,ko00002,ko01000	-	-	-	ICL
k59_143060_1	68219.JNXI01000017_gene7267	4.22e-55	182.0	COG2197@1|root,COG2197@2|Bacteria,2GJHH@201174|Actinobacteria	201174|Actinobacteria	T	Response regulator receiver	-	-	-	ko:K07696	ko02020,map02020	M00483	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
k59_240992_1	1027273.GZ77_15850	5.72e-21	96.3	COG5433@1|root,COG5433@2|Bacteria,1MXI8@1224|Proteobacteria,1SP0E@1236|Gammaproteobacteria	1224|Proteobacteria	L	Pfam Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
k59_135551_1	316067.Geob_1843	2.3e-08	56.6	COG1167@1|root,COG1167@2|Bacteria,1MV6F@1224|Proteobacteria,42MID@68525|delta/epsilon subdivisions,2WJYT@28221|Deltaproteobacteria,43UJC@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	helix_turn_helix gluconate operon transcriptional repressor	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2,GntR
k59_135551_2	926549.KI421517_gene455	9.33e-106	318.0	COG2234@1|root,COG2234@2|Bacteria,4NIQX@976|Bacteroidetes,47MWW@768503|Cytophagia	976|Bacteroidetes	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
k59_43629_1	1121396.KB892946_gene2897	1.4e-47	172.0	COG1033@1|root,COG1033@2|Bacteria,1MUE1@1224|Proteobacteria,42ME2@68525|delta/epsilon subdivisions,2WJRI@28221|Deltaproteobacteria,2MHZ1@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Sterol-sensing domain of SREBP cleavage-activation	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
k59_211270_1	1265505.ATUG01000002_gene1754	1.4e-131	389.0	COG1292@1|root,COG1292@2|Bacteria,1MV0K@1224|Proteobacteria,42N6Q@68525|delta/epsilon subdivisions,2WJVG@28221|Deltaproteobacteria,2MN1K@213118|Desulfobacterales	28221|Deltaproteobacteria	M	BCCT, betaine/carnitine/choline family transporter	-	-	-	ko:K02168,ko:K03451	-	-	-	-	ko00000,ko02000	2.A.15,2.A.15.1.3,2.A.15.1.4	-	-	BCCT
k59_135554_1	1121405.dsmv_2785	3.91e-78	247.0	COG1570@1|root,COG1570@2|Bacteria,1MUA4@1224|Proteobacteria,42MSB@68525|delta/epsilon subdivisions,2WJI6@28221|Deltaproteobacteria,2MHYI@213118|Desulfobacterales	28221|Deltaproteobacteria	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseA	-	3.1.11.6	ko:K03601	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
k59_240995_1	323097.Nham_3901	7.23e-76	252.0	COG1961@1|root,COG1961@2|Bacteria,1MVIE@1224|Proteobacteria,2TVFI@28211|Alphaproteobacteria,3JU9X@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	L	DNA invertase Pin	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17,Recombinase,Resolvase,Zn_ribbon_recom
k59_180214_1	266265.Bxe_C0838	4.81e-76	244.0	COG3547@1|root,COG3547@2|Bacteria,1MW0N@1224|Proteobacteria,2VWYN@28216|Betaproteobacteria,1K8UX@119060|Burkholderiaceae	28216|Betaproteobacteria	L	Transposase IS116/IS110/IS902 family	-	-	-	ko:K07486	-	-	-	-	ko00000	-	-	-	Transposase_20
k59_59698_1	1167006.UWK_01037	1.78e-46	154.0	COG0735@1|root,COG0735@2|Bacteria,1N4Z7@1224|Proteobacteria,42UD5@68525|delta/epsilon subdivisions,2WQSV@28221|Deltaproteobacteria,2MM4F@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Ferric uptake regulator family	-	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
k59_74471_2	1210884.HG799462_gene8969	1.36e-81	257.0	COG0649@1|root,COG0649@2|Bacteria,2IYN8@203682|Planctomycetes	203682|Planctomycetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	-	1.6.5.3	ko:K00333	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_49kDa
k59_43636_1	1123371.ATXH01000001_gene1284	1.43e-47	173.0	COG3005@1|root,COG3005@2|Bacteria,2GHZU@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	C	Doubled CXXCH motif (Paired_CXXCH_1)	-	-	-	-	-	-	-	-	-	-	-	-	Paired_CXXCH_1
k59_234208_1	1225184.ALXE01000045_gene470	2.62e-17	85.1	COG4658@1|root,COG4658@2|Bacteria,1MVY6@1224|Proteobacteria,1RMEU@1236|Gammaproteobacteria,3VXJ5@53335|Pantoea	1236|Gammaproteobacteria	C	Part of a membrane complex involved in electron transport	rnfD	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0044464,GO:0055114,GO:0071944	-	ko:K03614	-	-	-	-	ko00000	-	-	-	NQR2_RnfD_RnfE
k59_74478_1	595460.RRSWK_04245	5.67e-43	159.0	COG3210@1|root,COG3391@1|root,COG3210@2|Bacteria,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_149729_2	926554.KI912668_gene5153	1.11e-08	57.8	COG4696@1|root,COG4696@2|Bacteria	2|Bacteria	J	Protein conserved in bacteria	XK27_03185	-	-	ko:K16785	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	Acetyltransf_3,Hydrolase_3,PRA-PH
k59_127732_1	1499967.BAYZ01000154_gene1466	3.24e-18	85.1	COG0699@1|root,COG0699@2|Bacteria	2|Bacteria	T	ATPase. Has a role at an early stage in the morphogenesis of the spore coat	-	-	-	-	-	-	-	-	-	-	-	-	Dynamin_N
k59_59703_1	326423.RBAM_025970	2.27e-06	55.8	COG3275@1|root,COG3275@2|Bacteria,1VTXF@1239|Firmicutes,4H9Z1@91061|Bacilli,1ZBKQ@1386|Bacillus	91061|Bacilli	T	Histidine kinase	lytS	-	2.7.13.3	ko:K07704	ko02020,map02020	M00492	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	5TM-5TMR_LYT,GAF_3,HATPase_c,His_kinase
k59_135570_1	177437.HRM2_06920	2.13e-32	127.0	COG1726@1|root,COG1726@2|Bacteria,1MU36@1224|Proteobacteria,42PMT@68525|delta/epsilon subdivisions,2WK84@28221|Deltaproteobacteria,2MIE5@213118|Desulfobacterales	28221|Deltaproteobacteria	C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol	nqrA	-	1.6.5.8	ko:K00346	-	-	-	-	ko00000,ko01000	-	-	-	Fer4_10,NQRA,NQRA_SLBB
k59_135573_1	1121413.JMKT01000009_gene1913	7.88e-42	146.0	COG2181@1|root,COG2181@2|Bacteria,1RERF@1224|Proteobacteria,42RXQ@68525|delta/epsilon subdivisions,2WN8Q@28221|Deltaproteobacteria,2MACS@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	nitrate reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	Nitrate_red_gam
k59_211292_1	335543.Sfum_1329	8.54e-69	228.0	COG0348@1|root,COG1143@1|root,COG1152@1|root,COG0348@2|Bacteria,COG1143@2|Bacteria,COG1152@2|Bacteria,1MY5M@1224|Proteobacteria,43BPV@68525|delta/epsilon subdivisions,2WJVS@28221|Deltaproteobacteria,2MSKF@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_5,Fer4_7
k59_195243_1	335543.Sfum_0002	2.54e-35	122.0	COG0776@1|root,COG0776@2|Bacteria,1RH5Z@1224|Proteobacteria,42W2F@68525|delta/epsilon subdivisions,2WRUM@28221|Deltaproteobacteria,2MS8Q@213462|Syntrophobacterales	28221|Deltaproteobacteria	K	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control	ihfA	-	-	ko:K04764	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
k59_173055_1	1123376.AUIU01000019_gene1260	5.96e-08	53.1	2DDIC@1|root,32U1K@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF1634
k59_180231_1	768672.Desfe_1184	1.75e-36	133.0	COG0258@1|root,arCOG04050@2157|Archaea,2XPRH@28889|Crenarchaeota	28889|Crenarchaeota	L	Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double- stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. Acts as a genome stabilization factor that prevents flaps from equilibrating into	fen	-	-	ko:K04799	ko03030,ko03410,ko03450,map03030,map03410,map03450	-	-	-	ko00000,ko00001,ko01000,ko03032,ko03400,ko04147	-	-	-	XPG_I,XPG_N
k59_234217_2	1120963.KB894495_gene3327	1.25e-19	82.4	2E33E@1|root,32Y3I@2|Bacteria,1N9MJ@1224|Proteobacteria,1SETP@1236|Gammaproteobacteria,2Q54M@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_234217_3	1116375.VEJY3_09895	2.32e-24	103.0	2DMKC@1|root,32S64@2|Bacteria,1Q94U@1224|Proteobacteria,1TC3F@1236|Gammaproteobacteria,1XYYT@135623|Vibrionales	135623|Vibrionales	S	HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	HNH_3
k59_112604_1	335543.Sfum_0378	2.07e-91	281.0	COG0683@1|root,COG0683@2|Bacteria,1MX94@1224|Proteobacteria,42PYP@68525|delta/epsilon subdivisions,2WMA1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	PFAM Extracellular ligand-binding receptor	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
k59_218347_1	1121405.dsmv_2973	9.14e-17	77.8	COG1410@1|root,COG1410@2|Bacteria,1MV6G@1224|Proteobacteria,42Q13@68525|delta/epsilon subdivisions,2WJHD@28221|Deltaproteobacteria,2MJ10@213118|Desulfobacterales	28221|Deltaproteobacteria	E	PFAM dihydropteroate synthase DHPS	-	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
k59_218347_2	574087.Acear_1221	3.43e-64	203.0	COG5012@1|root,COG5012@2|Bacteria,1V1P0@1239|Firmicutes,24G08@186801|Clostridia,3WBKW@53433|Halanaerobiales	186801|Clostridia	S	Methionine synthase B12-binding module cap domain protein	-	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2
k59_180232_1	1121405.dsmv_1991	6.94e-91	278.0	COG1894@1|root,COG1894@2|Bacteria,1MV8F@1224|Proteobacteria,42N6N@68525|delta/epsilon subdivisions,2WJ1W@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Respiratory-chain NADH dehydrogenase domain 51 kDa subunit	nuoF-2	-	1.6.5.3	ko:K00334,ko:K00335	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx,Complex1_51K,NADH_4Fe-4S,SLBB
k59_195244_1	247634.GPB2148_14	2.75e-122	358.0	COG2801@1|root,COG2963@1|root,COG2801@2|Bacteria,COG2963@2|Bacteria,1PBHA@1224|Proteobacteria	1224|Proteobacteria	L	Transposase and inactivated derivatives	-	-	2.7.7.49	ko:K00986,ko:K07497	-	-	-	-	ko00000,ko01000	-	-	-	HTH_32,rve,rve_3
k59_55062_1	163908.KB235896_gene2472	8.09e-91	289.0	COG3385@1|root,COG3385@2|Bacteria,1G0M7@1117|Cyanobacteria,1HQC6@1161|Nostocales	1117|Cyanobacteria	L	transposase activity	-	-	-	-	-	-	-	-	-	-	-	-	DDE_5
k59_130871_2	1032480.MLP_22740	9.03e-10	63.2	COG3107@1|root,COG3107@2|Bacteria	2|Bacteria	M	peptidoglycan biosynthetic process	-	-	-	ko:K07121	-	-	-	-	ko00000	-	-	-	LppC
k59_92781_2	1278078.G419_02290	8.21e-58	193.0	COG5361@1|root,COG5361@2|Bacteria,2GRDZ@201174|Actinobacteria,4FWN7@85025|Nocardiaceae	201174|Actinobacteria	S	Protein of unknown function (DUF1254)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1214,DUF1254
k59_206687_1	335543.Sfum_0458	2.79e-100	306.0	COG1884@1|root,COG1884@2|Bacteria,1MUXX@1224|Proteobacteria,42P03@68525|delta/epsilon subdivisions,2WIPY@28221|Deltaproteobacteria,2MR53@213462|Syntrophobacterales	28221|Deltaproteobacteria	I	PFAM Methylmalonyl-CoA mutase	-	-	5.4.99.2	ko:K01848	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
k59_229303_1	795359.TOPB45_1372	2.68e-76	240.0	COG1180@1|root,COG1180@2|Bacteria,2GH3H@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	C	4Fe-4S single cluster domain	-	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
k59_1796_1	349161.Dred_3203	6e-61	198.0	COG1116@1|root,COG1116@2|Bacteria,1TSW5@1239|Firmicutes,25AZG@186801|Clostridia,261IG@186807|Peptococcaceae	186801|Clostridia	P	ABC-type nitrate sulfonate bicarbonate transport system ATPase component	-	-	-	ko:K02049	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	ABC_tran
k59_1796_2	485915.Dret_2296	2.85e-95	286.0	COG0600@1|root,COG0600@2|Bacteria,1MVAE@1224|Proteobacteria,42PYZ@68525|delta/epsilon subdivisions,2WK4B@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	inner membrane component	-	-	-	ko:K02050,ko:K15599	ko02010,map02010	M00188,M00442	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.16,3.A.1.17,3.A.1.17.3,3.A.1.17.6	-	-	BPD_transp_1
k59_1796_3	1123366.TH3_16824	3.37e-09	58.2	COG0715@1|root,COG0715@2|Bacteria,1MVRA@1224|Proteobacteria,2TQPE@28211|Alphaproteobacteria,2JPG6@204441|Rhodospirillales	204441|Rhodospirillales	P	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components	-	-	-	ko:K15598	ko02010,map02010	M00442	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.17.3,3.A.1.17.6	-	-	NMT1
k59_130881_1	1121468.AUBR01000070_gene1040	1.1e-82	259.0	COG0004@1|root,COG0004@2|Bacteria,1TQYG@1239|Firmicutes,247W1@186801|Clostridia,42F7G@68295|Thermoanaerobacterales	186801|Clostridia	P	TIGRFAM Ammonium transporter	nrgA	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
k59_214108_1	1121405.dsmv_1991	1.66e-93	285.0	COG1894@1|root,COG1894@2|Bacteria,1MV8F@1224|Proteobacteria,42N6N@68525|delta/epsilon subdivisions,2WJ1W@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Respiratory-chain NADH dehydrogenase domain 51 kDa subunit	nuoF-2	-	1.6.5.3	ko:K00334,ko:K00335	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx,Complex1_51K,NADH_4Fe-4S,SLBB
k59_1802_1	933262.AXAM01000017_gene3146	5.02e-26	96.7	COG1148@1|root,COG1148@2|Bacteria,1NA53@1224|Proteobacteria,42V92@68525|delta/epsilon subdivisions,2WS6E@28221|Deltaproteobacteria,2MM0X@213118|Desulfobacterales	28221|Deltaproteobacteria	C	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_8,Pyr_redox_2
k59_39864_1	985053.VMUT_1787	7.11e-29	117.0	COG0451@1|root,arCOG04762@2157|Archaea,2XQ3Z@28889|Crenarchaeota	28889|Crenarchaeota	M	PFAM NAD dependent epimerase dehydratase family	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase,GDP_Man_Dehyd
k59_70099_1	34506.g2227	3.34e-60	211.0	COG0524@1|root,COG0642@1|root,KOG0519@2759|Eukaryota,KOG2855@2759|Eukaryota	2759|Eukaryota	G	carbohydrate kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PfkB,Response_reg
k59_236959_1	1121405.dsmv_1096	8.34e-28	116.0	COG1132@1|root,COG1132@2|Bacteria,1MWTY@1224|Proteobacteria,42N23@68525|delta/epsilon subdivisions,2WKW2@28221|Deltaproteobacteria,2MMXV@213118|Desulfobacterales	28221|Deltaproteobacteria	V	ABC transporter transmembrane region	-	-	-	ko:K02021	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.110,3.A.1.112,3.A.1.113,3.A.1.117,3.A.1.21	-	-	ABC_membrane,ABC_tran
k59_199054_1	1101195.Meth11DRAFT_1563	1.1e-76	240.0	COG4974@1|root,COG4974@2|Bacteria,1MVAN@1224|Proteobacteria,2VHUC@28216|Betaproteobacteria,2KKW1@206350|Nitrosomonadales	206350|Nitrosomonadales	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
k59_32188_1	2850.Phatr29758	1.61e-42	161.0	COG0308@1|root,KOG1046@2759|Eukaryota,2XF5U@2836|Bacillariophyta	2836|Bacillariophyta	E	ERAP1-like C-terminal domain	-	-	-	ko:K08776	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	ERAP1_C,Peptidase_M1
k59_39876_1	880072.Desac_0497	1.84e-20	82.4	2FJKA@1|root,34B9P@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_39876_3	880072.Desac_0495	3.51e-73	221.0	2F79F@1|root,33ZQP@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_206714_1	1123320.KB889719_gene7363	0.000194	48.5	COG0265@1|root,COG0265@2|Bacteria,2GJ96@201174|Actinobacteria	201174|Actinobacteria	O	Peptidase s1 and s6 chymotrypsin hap	-	-	-	ko:K08372	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ_2,Trypsin_2
k59_39878_2	1403313.AXBR01000007_gene363	7.52e-28	103.0	COG0776@1|root,COG0776@2|Bacteria,1V9XQ@1239|Firmicutes,4HKF2@91061|Bacilli,1ZH48@1386|Bacillus	91061|Bacilli	L	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions	hbs	GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009889,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2001141	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
k59_236973_1	1265505.ATUG01000001_gene2967	5.49e-76	235.0	COG0834@1|root,COG0834@2|Bacteria,1MV5D@1224|Proteobacteria,43BDC@68525|delta/epsilon subdivisions,2WK43@28221|Deltaproteobacteria,2MHPC@213118|Desulfobacterales	28221|Deltaproteobacteria	ET	Bacterial extracellular solute-binding proteins, family 3	aapJ	-	-	ko:K09969	ko02010,map02010	M00232	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3.18,3.A.1.3.7,3.A.1.3.8	-	-	SBP_bac_3
k59_92796_1	1125863.JAFN01000001_gene2314	1.18e-57	185.0	COG2120@1|root,COG2120@2|Bacteria,1MUTM@1224|Proteobacteria,42Q20@68525|delta/epsilon subdivisions,2WP8Q@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	GlcNAc-PI de-N-acetylase	-	-	-	ko:K01463	-	-	-	-	ko00000,ko01000	-	-	-	PIG-L
k59_77885_1	634176.NT05HA_0259	2.19e-47	176.0	COG3209@1|root,COG3501@1|root,COG3209@2|Bacteria,COG3501@2|Bacteria,1MU7Q@1224|Proteobacteria,1RMZS@1236|Gammaproteobacteria,1Y9W8@135625|Pasteurellales	135625|Pasteurellales	M	RHS protein	-	-	-	ko:K11904	ko03070,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	Phage_GPD,RHS,RHS_repeat
k59_108033_1	96561.Dole_3250	1.64e-62	204.0	COG3039@1|root,COG3039@2|Bacteria,1QQ9Q@1224|Proteobacteria,42S7X@68525|delta/epsilon subdivisions,2WNJ2@28221|Deltaproteobacteria,2MJG4@213118|Desulfobacterales	28221|Deltaproteobacteria	L	PFAM transposase IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DUF772
k59_55103_1	177437.HRM2_11180	1.24e-58	188.0	29GM5@1|root,303IT@2|Bacteria,1RG3T@1224|Proteobacteria,42RUX@68525|delta/epsilon subdivisions,2WNMJ@28221|Deltaproteobacteria,2MJY1@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4390)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4390
k59_153778_1	1121405.dsmv_0822	4.26e-72	220.0	COG0517@1|root,COG0517@2|Bacteria,1QUKQ@1224|Proteobacteria,42TPD@68525|delta/epsilon subdivisions,2WQQ5@28221|Deltaproteobacteria,2MK07@213118|Desulfobacterales	28221|Deltaproteobacteria	S	PFAM CBS domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS
k59_123309_1	706587.Desti_0904	4.04e-83	256.0	COG4177@1|root,COG4177@2|Bacteria,1NNMV@1224|Proteobacteria,42PQV@68525|delta/epsilon subdivisions,2WJDV@28221|Deltaproteobacteria	2|Bacteria	U	PFAM Branched-chain amino acid transport system permease component	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
k59_85174_1	63737.Npun_R5897	0.000775	47.4	COG0642@1|root,COG0784@1|root,COG2202@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG2205@2|Bacteria,1G09B@1117|Cyanobacteria,1HRFM@1161|Nostocales	1117|Cyanobacteria	T	response regulator, receiver	-	-	2.7.13.3	ko:K11527	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	CBS,GAF,GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
k59_39885_1	521000.PROVRETT_06010	1.24e-56	191.0	28J9D@1|root,2Z94E@2|Bacteria,1QE0C@1224|Proteobacteria,1RZ22@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	P22 coat protein - gene protein 5	-	-	-	-	-	-	-	-	-	-	-	-	P22_CoatProtein
k59_123312_1	1265505.ATUG01000001_gene3023	1.84e-107	317.0	COG0685@1|root,COG0685@2|Bacteria,1MWQ3@1224|Proteobacteria,42PKP@68525|delta/epsilon subdivisions,2WK0A@28221|Deltaproteobacteria,2MIZB@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Methylenetetrahydrofolate reductase	-	-	-	-	-	-	-	-	-	-	-	-	MTHFR
k59_236988_2	1158614.I592_01226	5.86e-16	74.3	2DJXV@1|root,307TG@2|Bacteria,1TVRS@1239|Firmicutes,4IABJ@91061|Bacilli,4B5C3@81852|Enterococcaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_55113_1	909663.KI867150_gene2362	7.42e-21	86.7	COG2391@1|root,COG2391@2|Bacteria,1RIWE@1224|Proteobacteria,42QRV@68525|delta/epsilon subdivisions,2WMUE@28221|Deltaproteobacteria,2MRP5@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Sulphur transport	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
k59_145986_1	1265505.ATUG01000002_gene1947	3.73e-43	159.0	COG0741@1|root,COG1388@1|root,COG0741@2|Bacteria,COG1388@2|Bacteria,1MWKE@1224|Proteobacteria,42QM3@68525|delta/epsilon subdivisions,2WKI2@28221|Deltaproteobacteria,2MI4S@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Lysin motif	-	-	-	ko:K08307	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	LysM,SLT
k59_16952_1	933262.AXAM01000002_gene503	2.71e-82	262.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,1MU1Q@1224|Proteobacteria,42ND6@68525|delta/epsilon subdivisions,2WIJS@28221|Deltaproteobacteria,2MHY5@213118|Desulfobacterales	28221|Deltaproteobacteria	G	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	Carb_kinase,YjeF_N
k59_85179_1	335543.Sfum_4069	1.21e-61	203.0	COG0683@1|root,COG0683@2|Bacteria,1MXR4@1224|Proteobacteria,42MXX@68525|delta/epsilon subdivisions,2WKJM@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	PFAM Extracellular ligand-binding receptor	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
k59_39891_1	879212.DespoDRAFT_03764	2.01e-61	201.0	COG0502@1|root,COG0502@2|Bacteria,1MXK0@1224|Proteobacteria,42M3U@68525|delta/epsilon subdivisions,2WJQ6@28221|Deltaproteobacteria,2MHKZ@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Biotin and Thiamin Synthesis associated	thiH	-	4.1.99.19	ko:K03150	ko00730,ko01100,map00730,map01100	-	R10246	RC01434,RC03095	ko00000,ko00001,ko01000	-	-	-	BATS,Radical_SAM
k59_2289_1	1124983.PFLCHA0_c30360	2.47e-88	282.0	COG3501@1|root,COG3501@2|Bacteria,1MU7Q@1224|Proteobacteria,1RMZS@1236|Gammaproteobacteria,1YMYR@136843|Pseudomonas fluorescens group	1236|Gammaproteobacteria	U	type VI secretion system	-	-	-	ko:K11904	ko03070,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	Gp5_C,Phage_GPD
k59_78393_1	1178482.BJB45_01325	1.19e-34	137.0	COG4191@1|root,COG4192@1|root,COG4191@2|Bacteria,COG4192@2|Bacteria,1RCM9@1224|Proteobacteria,1RQIN@1236|Gammaproteobacteria,1XHA0@135619|Oceanospirillales	135619|Oceanospirillales	T	Integral membrane sensor signal transduction histidine kinase	-	-	2.7.13.3	ko:K08475,ko:K10125	ko02020,map02020	M00503,M00504	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
k59_169095_1	56780.SYN_02850	2.02e-72	229.0	COG0167@1|root,COG0167@2|Bacteria,1MU7C@1224|Proteobacteria,42M46@68525|delta/epsilon subdivisions,2WJ7G@28221|Deltaproteobacteria,2MQCF@213462|Syntrophobacterales	28221|Deltaproteobacteria	F	Catalyzes the conversion of dihydroorotate to orotate	pyrD	GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	1.3.1.14,1.3.5.2	ko:K00254,ko:K02823,ko:K17828	ko00240,ko01100,map00240,map01100	M00051	R01868,R01869	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
k59_222444_1	1232437.KL661989_gene449	3.7e-84	256.0	COG0559@1|root,COG0559@2|Bacteria,1MU25@1224|Proteobacteria,42NUE@68525|delta/epsilon subdivisions,2WJYH@28221|Deltaproteobacteria,2MI0A@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
k59_93392_1	1121396.KB893100_gene4313	3.41e-11	62.4	COG1035@1|root,COG4656@1|root,COG1035@2|Bacteria,COG4656@2|Bacteria,1NQN7@1224|Proteobacteria,42MGI@68525|delta/epsilon subdivisions,2WKNC@28221|Deltaproteobacteria,2MIJN@213118|Desulfobacterales	28221|Deltaproteobacteria	C	4Fe-4S ferredoxin iron-sulfur binding domain protein	hdrD	-	-	-	-	-	-	-	-	-	-	-	Fer4_10,Fer4_17,Fer4_8,FlpD,FrhB_FdhB_C
k59_93392_2	1121396.KB893100_gene4312	8.68e-66	213.0	COG1150@1|root,COG1150@2|Bacteria,1QWNB@1224|Proteobacteria,43BTA@68525|delta/epsilon subdivisions,2X741@28221|Deltaproteobacteria,2MI1V@213118|Desulfobacterales	28221|Deltaproteobacteria	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_22
k59_40385_2	429009.Adeg_1078	2.1e-46	165.0	COG1148@1|root,COG1908@1|root,COG1148@2|Bacteria,COG1908@2|Bacteria,1UT78@1239|Firmicutes,24A6H@186801|Clostridia,42FPJ@68295|Thermoanaerobacterales	186801|Clostridia	C	PFAM methyl-viologen-reducing hydrogenase delta subunit	-	-	-	ko:K16886	-	-	-	-	ko00000	-	-	-	Fer4,Fer4_9,FlpD,Pyr_redox_2
k59_32729_1	768671.ThimaDRAFT_4913	2.9e-22	97.8	COG3464@1|root,COG3464@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K07485	-	-	-	-	ko00000	-	-	-	DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3
k59_70574_1	1123405.AUMM01000051_gene1831	2.26e-72	228.0	COG4177@1|root,COG4177@2|Bacteria,1TPMZ@1239|Firmicutes,4HDIU@91061|Bacilli,26PUU@186821|Sporolactobacillaceae	91061|Bacilli	E	Branched-chain amino acid transport system / permease component	livM	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
k59_237594_2	84531.JMTZ01000038_gene3638	1.31e-22	97.8	COG3500@1|root,COG3500@2|Bacteria,1R67C@1224|Proteobacteria,1S49W@1236|Gammaproteobacteria,1X9ZI@135614|Xanthomonadales	135614|Xanthomonadales	S	Phage late control gene D protein (GPD)	-	-	-	-	-	-	-	-	-	-	-	-	Phage_GPD
k59_40395_1	335543.Sfum_0854	7.52e-54	185.0	COG3290@1|root,COG3852@1|root,COG3290@2|Bacteria,COG3852@2|Bacteria,1MVN6@1224|Proteobacteria,43BPS@68525|delta/epsilon subdivisions,2X710@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Signal transduction histidine kinase, nitrogen specific	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
k59_115933_1	243159.AFE_1843	5.32e-101	313.0	COG0021@1|root,COG0021@2|Bacteria,1MUEY@1224|Proteobacteria,1SJQ1@1236|Gammaproteobacteria,2NDRU@225057|Acidithiobacillales	225057|Acidithiobacillales	G	Transketolase, thiamine diphosphate binding domain	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
k59_78414_1	1499967.BAYZ01000028_gene1309	3.77e-127	367.0	COG0410@1|root,COG0410@2|Bacteria,2NNXF@2323|unclassified Bacteria	2|Bacteria	E	ABC transporter	livF	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
k59_237609_1	177437.HRM2_22700	6.82e-93	290.0	COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,42M88@68525|delta/epsilon subdivisions,2WIZI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	KT	PFAM sigma-54 factor interaction domain-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,PAS_9,Sigma54_activat
k59_131433_1	1112217.PPL19_13420	9.57e-05	49.3	COG5524@1|root,COG5524@2|Bacteria,1N49E@1224|Proteobacteria,1SNQD@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Bacteriorhodopsin-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Bac_rhodopsin
k59_161825_1	1116369.KB890024_gene2499	9.66e-07	57.4	COG0740@1|root,COG0740@2|Bacteria,1MV46@1224|Proteobacteria,2U07E@28211|Alphaproteobacteria,43J99@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	OU	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP1	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
k59_184514_1	529507.PMI2407	4.3e-11	68.6	COG1840@1|root,COG1840@2|Bacteria,1MWWI@1224|Proteobacteria,1RRWU@1236|Gammaproteobacteria,3Z1V0@583|Proteus	1236|Gammaproteobacteria	P	Bacterial extracellular solute-binding protein	pgtC	-	-	ko:K08478	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	SBP_bac_6
k59_237611_1	1499967.BAYZ01000171_gene5606	2.43e-10	60.5	COG1277@1|root,COG1277@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2
k59_237611_2	1122223.KB890700_gene2006	1.89e-16	80.9	COG1131@1|root,COG1131@2|Bacteria	2|Bacteria	V	ATPase activity	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
k59_40409_1	472759.Nhal_1309	5.16e-75	245.0	COG1657@1|root,COG1657@2|Bacteria,1MUIP@1224|Proteobacteria,1S118@1236|Gammaproteobacteria,1X0F2@135613|Chromatiales	135613|Chromatiales	I	Squalene-hopene cyclase N-terminal domain	-	-	4.2.1.129,5.4.99.17	ko:K06045	ko00909,ko01110,map00909,map01110	-	R07322,R07323	RC01850,RC01851	ko00000,ko00001,ko01000	-	-	-	SQHop_cyclase_C,SQHop_cyclase_N
k59_207271_1	1443122.Z958_12325	1.2e-20	92.4	COG0619@1|root,COG0619@2|Bacteria,1TQ0E@1239|Firmicutes,248AB@186801|Clostridia,36FFB@31979|Clostridiaceae	186801|Clostridia	P	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates	ecfT	-	-	ko:K16783,ko:K16785	ko02010,map02010	M00581,M00582	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.25,3.A.1.25.1,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	CbiQ
k59_207271_2	177439.DP2773	7.08e-17	78.2	COG0742@1|root,COG0742@2|Bacteria,1MXKW@1224|Proteobacteria,42U1F@68525|delta/epsilon subdivisions,2WQQM@28221|Deltaproteobacteria,2MK2T@213118|Desulfobacterales	28221|Deltaproteobacteria	L	PFAM conserved	-	-	2.1.1.171	ko:K08316	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Cons_hypoth95
k59_55738_1	879212.DespoDRAFT_03678	1.57e-37	134.0	COG0345@1|root,COG0345@2|Bacteria,1R5J1@1224|Proteobacteria,42P7F@68525|delta/epsilon subdivisions,2WJW9@28221|Deltaproteobacteria,2MIK9@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline	proC	-	1.5.1.2	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	M00015	R01248,R01251,R03291,R03293	RC00054,RC00083	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_0899	F420_oxidored,P5CR_dimer
k59_6013_1	1121403.AUCV01000056_gene3012	2.57e-46	165.0	COG0661@1|root,COG0661@2|Bacteria,1MU1Z@1224|Proteobacteria,42N87@68525|delta/epsilon subdivisions,2WK1B@28221|Deltaproteobacteria,2MHU5@213118|Desulfobacterales	28221|Deltaproteobacteria	S	pfam abc-1	-	-	-	ko:K03688	-	-	-	-	ko00000	-	-	-	ABC1,APH
k59_158702_1	765913.ThidrDRAFT_2390	3.47e-40	141.0	COG1280@1|root,COG1280@2|Bacteria,1RF18@1224|Proteobacteria,1S4TM@1236|Gammaproteobacteria,1WYI1@135613|Chromatiales	135613|Chromatiales	E	PFAM Lysine exporter protein (LYSE YGGA)	-	-	-	-	-	-	-	-	-	-	-	-	LysE
k59_158702_2	1380394.JADL01000004_gene5996	8.48e-05	44.3	COG1123@1|root,COG4172@2|Bacteria,1MU09@1224|Proteobacteria,2TQNH@28211|Alphaproteobacteria,2JR2G@204441|Rhodospirillales	204441|Rhodospirillales	P	Oligopeptide/dipeptide transporter, C-terminal region	-	-	-	ko:K02031,ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
k59_21837_1	1265505.ATUG01000002_gene1865	6.53e-51	186.0	COG1198@1|root,COG1198@2|Bacteria,1MUUZ@1224|Proteobacteria,42MNH@68525|delta/epsilon subdivisions,2WJ4G@28221|Deltaproteobacteria,2MINK@213118|Desulfobacterales	28221|Deltaproteobacteria	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,ResIII
k59_227370_1	1150621.SMUL_3266	5.82e-53	168.0	2B9ZZ@1|root,323DM@2|Bacteria,1MZ6J@1224|Proteobacteria,42WB2@68525|delta/epsilon subdivisions,2YRYT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	COG NOG15344 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_227374_1	1038866.KB902791_gene3353	1.8e-39	145.0	COG0604@1|root,COG0604@2|Bacteria,1QWJV@1224|Proteobacteria,2TX01@28211|Alphaproteobacteria,3JRM5@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	Alcohol dehydrogenase GroES-like domain	-	-	1.1.1.1	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
k59_219680_2	96561.Dole_0541	1.92e-05	44.3	COG0718@1|root,COG0718@2|Bacteria,1RGZD@1224|Proteobacteria,42TGQ@68525|delta/epsilon subdivisions,2WQ6R@28221|Deltaproteobacteria,2MK5K@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection	-	-	-	ko:K09747	-	-	-	-	ko00000	-	-	-	YbaB_DNA_bd
k59_181559_1	225937.HP15_1649	1.04e-24	107.0	COG1167@1|root,COG1167@2|Bacteria,1MV6F@1224|Proteobacteria,1RMQ0@1236|Gammaproteobacteria,465KT@72275|Alteromonadaceae	1236|Gammaproteobacteria	K	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2,GntR
k59_181559_2	1122182.KB903833_gene5364	1.98e-29	118.0	COG0611@1|root,COG0611@2|Bacteria,2GP6E@201174|Actinobacteria,4DADB@85008|Micromonosporales	201174|Actinobacteria	H	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1	thiL	GO:0008150,GO:0040007	2.7.4.16	ko:K00946	ko00730,ko01100,map00730,map01100	M00127	R00617	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv2977c	AIRS,AIRS_C
k59_67956_1	1227454.C446_10075	2.71e-11	63.2	COG0521@1|root,arCOG00214@2157|Archaea,2XXIW@28890|Euryarchaeota,23VQZ@183963|Halobacteria	183963|Halobacteria	H	Molybdenum cofactor synthesis	-	-	2.7.7.75	ko:K03638	ko00790,ko01100,map00790,map01100	-	R09726	RC00002	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth
k59_67956_2	937777.Deipe_0663	1.06e-21	95.1	COG2896@1|root,COG2896@2|Bacteria,1WIGS@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	H	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate	moaA	-	4.1.99.22	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394	RC03420	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Mob_synth_C,Radical_SAM
k59_166420_1	1121405.dsmv_1630	8.17e-81	249.0	COG0204@1|root,COG0204@2|Bacteria,1MVWG@1224|Proteobacteria,42PBW@68525|delta/epsilon subdivisions,2WJV5@28221|Deltaproteobacteria,2MIXQ@213118|Desulfobacterales	28221|Deltaproteobacteria	I	PFAM phospholipid glycerol acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
k59_30063_1	194439.CT0108	1.46e-20	96.7	COG2203@1|root,COG3829@1|root,COG2203@2|Bacteria,COG3829@2|Bacteria,1FESR@1090|Chlorobi	1090|Chlorobi	KT	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HTH_8,Sigma54_activat
k59_52919_1	497964.CfE428DRAFT_0736	5.67e-83	266.0	COG0265@1|root,COG0265@2|Bacteria,46SZ1@74201|Verrucomicrobia	74201|Verrucomicrobia	O	Domain present in PSD-95, Dlg, and ZO-1/2.	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2
k59_196738_1	313606.M23134_04935	2.41e-95	310.0	COG1538@1|root,COG1538@2|Bacteria,4NHGK@976|Bacteroidetes	976|Bacteroidetes	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC_sub_bind,OEP
k59_151352_1	933262.AXAM01000001_gene342	2.56e-54	180.0	COG3383@1|root,COG3383@2|Bacteria,1QW12@1224|Proteobacteria,43BQY@68525|delta/epsilon subdivisions,2X5UH@28221|Deltaproteobacteria,2MHPH@213118|Desulfobacterales	28221|Deltaproteobacteria	C	2Fe-2S iron-sulfur cluster binding domain	sfrA	GO:0003674,GO:0003824,GO:0003954,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016651,GO:0044237,GO:0044424,GO:0044464,GO:0045333,GO:0048037,GO:0051536,GO:0051540,GO:0055114,GO:0071944	1.17.1.10	ko:K05299	ko00680,ko00720,ko01100,ko01120,ko01200,map00680,map00720,map01100,map01120,map01200	M00377	R00134	RC02796	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_4,Fer4,Fer4_10,Fer4_7,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
k59_151352_2	1121405.dsmv_3043	7e-27	108.0	COG3383@1|root,COG3383@2|Bacteria,1QTZB@1224|Proteobacteria,42SPZ@68525|delta/epsilon subdivisions,2WIV9@28221|Deltaproteobacteria,2MIGI@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM molybdopterin oxidoreductase	-	-	1.17.1.10,1.17.1.9	ko:K00123,ko:K05299	ko00630,ko00680,ko00720,ko01100,ko01120,ko01200,map00630,map00680,map00720,map01100,map01120,map01200	M00377	R00134,R00519	RC02796	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_4,Fer4,Fer4_7,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
k59_166435_2	33876.JNXY01000017_gene7354	4.37e-08	55.5	COG2197@1|root,COG2197@2|Bacteria,2GN80@201174|Actinobacteria,4DHHH@85008|Micromonosporales	201174|Actinobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
k59_181582_1	933262.AXAM01000030_gene824	2.27e-49	173.0	COG3437@1|root,COG3437@2|Bacteria,1P1A3@1224|Proteobacteria,42MD7@68525|delta/epsilon subdivisions,2WJH1@28221|Deltaproteobacteria,2MJF7@213118|Desulfobacterales	28221|Deltaproteobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	HD,HD_5,Response_reg
k59_166438_1	1121324.CLIT_5c01610	5.74e-29	112.0	COG0414@1|root,COG0414@2|Bacteria,1TP7A@1239|Firmicutes,248AN@186801|Clostridia,25T51@186804|Peptostreptococcaceae	186801|Clostridia	H	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate	panC	-	6.3.2.1	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R02473	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_ligase
k59_166438_2	264732.Moth_2131	9.95e-38	140.0	COG2206@1|root,COG2206@2|Bacteria,1V6WM@1239|Firmicutes,24FPG@186801|Clostridia,42J9V@68295|Thermoanaerobacterales	186801|Clostridia	T	HDOD domain	-	-	-	-	-	-	-	-	-	-	-	-	HD,HD_5
k59_30101_1	1232410.KI421424_gene1610	3.23e-19	87.8	COG1295@1|root,COG1295@2|Bacteria,1QICW@1224|Proteobacteria,42MBW@68525|delta/epsilon subdivisions,2WK2Z@28221|Deltaproteobacteria,43SWT@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	PFAM ribonuclease BN	-	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Rrf2,Virul_fac_BrkB
k59_219714_2	665029.EAMY_0658	1.51e-05	48.9	COG1186@1|root,COG1186@2|Bacteria,1MUAW@1224|Proteobacteria,1RP9Z@1236|Gammaproteobacteria,3X5K2@551|Erwinia	1236|Gammaproteobacteria	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016149,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
k59_242405_1	118173.KB235914_gene646	1.65e-83	257.0	COG3385@1|root,COG3385@2|Bacteria	2|Bacteria	L	transposase activity	-	-	-	-	-	-	-	-	-	-	-	-	DDE_5,DDE_Tnp_1
k59_52953_1	706587.Desti_4234	1.1e-98	293.0	COG0410@1|root,COG0410@2|Bacteria,1MUR3@1224|Proteobacteria,42R5R@68525|delta/epsilon subdivisions,2WMRR@28221|Deltaproteobacteria,2MR65@213462|Syntrophobacterales	28221|Deltaproteobacteria	E	PFAM ABC transporter	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
k59_52953_2	913865.DOT_4545	2.77e-20	87.8	COG0411@1|root,COG0411@2|Bacteria,1V7H4@1239|Firmicutes,2510H@186801|Clostridia,265BZ@186807|Peptococcaceae	186801|Clostridia	E	Branched-chain amino acid ATP-binding cassette transporter	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
k59_68000_1	765911.Thivi_2283	2.09e-114	356.0	COG0542@1|root,COG0542@2|Bacteria,1MVBH@1224|Proteobacteria,1RMZH@1236|Gammaproteobacteria,1WX5Q@135613|Chromatiales	135613|Chromatiales	O	associated with various cellular activities	-	-	-	ko:K11907	ko02025,ko03070,map02025,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	AAA,AAA_2,ClpB_D2-small
k59_181610_1	296587.XP_002500451.1	1.1e-69	218.0	COG0214@1|root,KOG1606@2759|Eukaryota,37KWB@33090|Viridiplantae,34H49@3041|Chlorophyta	3041|Chlorophyta	H	Belongs to the PdxS SNZ family	-	-	4.3.3.6	ko:K06215	ko00750,map00750	-	R07456	RC00010,RC01783,RC03043	ko00000,ko00001,ko01000	-	-	-	SOR_SNZ
k59_68013_1	1307759.JOMJ01000004_gene3008	1.81e-70	222.0	COG3016@1|root,COG3016@2|Bacteria,1MX1I@1224|Proteobacteria,42U2R@68525|delta/epsilon subdivisions,2WMNG@28221|Deltaproteobacteria,2MBCH@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Haem-binding uptake, Tiki superfamily, ChaN	-	-	-	-	-	-	-	-	-	-	-	-	Cofac_haem_bdg
k59_45237_1	744872.Spica_1949	2.04e-17	90.9	COG3233@1|root,COG3233@2|Bacteria,2J7B8@203691|Spirochaetes	203691|Spirochaetes	S	deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_22610_1	998088.B565_1525	1.78e-08	59.3	2EP36@1|root,33GPZ@2|Bacteria,1NHCW@1224|Proteobacteria,1SGB0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Lipid A 3-O-deacylase (PagL)	-	-	-	-	-	-	-	-	-	-	-	-	PagL
k59_22610_2	243233.MCA0363	6.24e-09	56.6	COG1463@1|root,COG3008@1|root,COG1463@2|Bacteria,COG3008@2|Bacteria,1MU1T@1224|Proteobacteria,1RN89@1236|Gammaproteobacteria,1XEQ8@135618|Methylococcales	135618|Methylococcales	Q	MlaD protein	pqiB	-	-	ko:K06192	-	-	-	-	ko00000	-	-	-	MlaD
k59_219738_1	555779.Dthio_PD3704	1.35e-84	267.0	COG4974@1|root,COG4974@2|Bacteria,1RC0C@1224|Proteobacteria,42W1W@68525|delta/epsilon subdivisions,2WRTZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	PFAM transposase IS66	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS66
k59_166475_1	177437.HRM2_11340	1.36e-10	63.2	COG3149@1|root,COG3149@2|Bacteria,1NEZ3@1224|Proteobacteria,42WMP@68525|delta/epsilon subdivisions,2WR67@28221|Deltaproteobacteria,2MKKX@213118|Desulfobacterales	28221|Deltaproteobacteria	U	Type II secretion system (T2SS), protein M	-	-	-	ko:K02462	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSM
k59_166478_1	1304880.JAGB01000002_gene2153	2.61e-28	110.0	COG1595@1|root,COG1595@2|Bacteria,1TS3M@1239|Firmicutes,24IW2@186801|Clostridia	186801|Clostridia	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	algU	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
k59_219747_1	1499967.BAYZ01000163_gene6590	4.94e-61	192.0	2DTSB@1|root,33MG4@2|Bacteria	2|Bacteria	S	Tripartite ATP-independent periplasmic transporters, DctQ component	-	-	-	-	-	-	-	-	-	-	-	-	DctQ
k59_196811_1	1121405.dsmv_3589	4.18e-05	45.1	COG0087@1|root,COG0087@2|Bacteria,1MUST@1224|Proteobacteria,42NV2@68525|delta/epsilon subdivisions,2WNJ1@28221|Deltaproteobacteria,2MJKX@213118|Desulfobacterales	28221|Deltaproteobacteria	J	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit	rplC	-	-	ko:K02906	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L3
k59_196811_2	933262.AXAM01000052_gene1991	5.12e-60	191.0	COG0088@1|root,COG0088@2|Bacteria,1MXPF@1224|Proteobacteria,42MPW@68525|delta/epsilon subdivisions,2WN96@28221|Deltaproteobacteria,2MJHZ@213118|Desulfobacterales	28221|Deltaproteobacteria	J	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome	rplD	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02926	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L4
k59_22639_1	56780.SYN_01481	2.34e-27	115.0	COG2114@1|root,COG4252@1|root,COG2114@2|Bacteria,COG4252@2|Bacteria,1MV1V@1224|Proteobacteria,42N5S@68525|delta/epsilon subdivisions,2WIUS@28221|Deltaproteobacteria,2MQZ2@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	Adenylyl cyclase class-3 4 guanylyl cyclase	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	CHASE2,Guanylate_cyc
k59_181635_1	269799.Gmet_0072	5.22e-79	248.0	COG0182@1|root,COG0182@2|Bacteria,1MUPM@1224|Proteobacteria,42MJ2@68525|delta/epsilon subdivisions,2WJQB@28221|Deltaproteobacteria,43UJ9@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)	mtnA	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	5.3.1.23	ko:K08963	ko00270,ko01100,map00270,map01100	M00034	R04420	RC01151	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_0072	IF-2B
k59_68041_1	1380391.JIAS01000020_gene1537	1.24e-66	214.0	COG1744@1|root,COG1744@2|Bacteria,1MVU5@1224|Proteobacteria,2TTTH@28211|Alphaproteobacteria,2JQGQ@204441|Rhodospirillales	204441|Rhodospirillales	S	ABC transporter substrate-binding protein PnrA-like	-	-	-	-	-	-	-	-	-	-	-	-	Bmp
k59_30174_1	667014.Thein_1409	5.79e-66	226.0	COG0574@1|root,COG3848@1|root,COG0574@2|Bacteria,COG3848@2|Bacteria,2GGWR@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	GT	Pyruvate phosphate dikinase, PEP/pyruvate binding domain	-	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PPDK_N
k59_181639_2	177437.HRM2_28000	5.19e-94	284.0	COG0535@1|root,COG0535@2|Bacteria,1MUQP@1224|Proteobacteria,42M55@68525|delta/epsilon subdivisions,2WIKM@28221|Deltaproteobacteria,2MJ60@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM Radical SAM domain protein	-	-	-	ko:K22227	-	-	-	-	ko00000	-	-	-	Fer4_12,Fer4_14,Radical_SAM,SPASM
k59_166516_1	1183438.GKIL_0288	2.15e-13	73.2	COG0451@1|root,COG0451@2|Bacteria,1G02N@1117|Cyanobacteria	1117|Cyanobacteria	GM	Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction	fcl	-	1.1.1.271	ko:K02377	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R05692	RC01014	ko00000,ko00001,ko01000	-	-	-	Epimerase
k59_166516_2	1194165.CAJF01000006_gene2462	1.4e-19	87.0	COG0413@1|root,COG0413@2|Bacteria,2GJP6@201174|Actinobacteria,4FM52@85023|Microbacteriaceae	201174|Actinobacteria	H	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate	panB	GO:0000287,GO:0003674,GO:0003824,GO:0003864,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016020,GO:0016053,GO:0016740,GO:0016741,GO:0016742,GO:0019752,GO:0032787,GO:0034641,GO:0040007,GO:0042364,GO:0042398,GO:0043167,GO:0043169,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046872,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:0072330,GO:1901564,GO:1901566,GO:1901576	2.1.2.11	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R01226	RC00022,RC00200	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_transf
k59_22666_1	595536.ADVE02000002_gene4225	9.33e-26	106.0	COG1116@1|root,COG1116@2|Bacteria,1R7ZX@1224|Proteobacteria,2U1V1@28211|Alphaproteobacteria,370A5@31993|Methylocystaceae	28211|Alphaproteobacteria	P	ATPases associated with a variety of cellular activities	-	-	-	ko:K02049	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	ABC_tran
k59_53013_1	445685.E3SKK5_9CAUD	1.81e-90	275.0	4QBWS@10239|Viruses,4QWQM@35237|dsDNA viruses  no RNA stage,4QUHG@28883|Caudovirales,4QI4T@10662|Myoviridae	10662|Myoviridae	S	phosphate ion transmembrane transport	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_196857_1	429009.Adeg_1312	1.79e-28	111.0	COG0631@1|root,COG0631@2|Bacteria,1V6K5@1239|Firmicutes,24JD4@186801|Clostridia,42EM8@68295|Thermoanaerobacterales	186801|Clostridia	T	protein phosphatase 2C domain protein	prpC	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C,PP2C_2,SpoIIE
k59_30212_1	933262.AXAM01000005_gene2515	3.68e-38	133.0	COG1886@1|root,COG1886@2|Bacteria,1RGWT@1224|Proteobacteria,42TQB@68525|delta/epsilon subdivisions,2WQCQ@28221|Deltaproteobacteria,2MKA6@213118|Desulfobacterales	28221|Deltaproteobacteria	N	Flagellar motor switch protein FliN	fliN	-	-	ko:K02417	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	FliMN_C
k59_22677_3	457570.Nther_2850	1.14e-26	106.0	COG0636@1|root,COG0636@2|Bacteria,1V1B0@1239|Firmicutes,24G2R@186801|Clostridia	186801|Clostridia	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	-	-	-	-	-	-	-	-	-	-	-	-	ATP-synt_C
k59_242456_1	1298867.AUES01000051_gene4511	3.17e-50	182.0	COG0771@1|root,COG2931@1|root,COG4625@1|root,COG0771@2|Bacteria,COG2931@2|Bacteria,COG4625@2|Bacteria,1MU7T@1224|Proteobacteria,2TRVY@28211|Alphaproteobacteria,3K2H3@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	Q	Haemolysin-type calcium-binding repeat (2 copies)	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP,HemolysinCabind
k59_6832_1	1121405.dsmv_1683	6.52e-118	356.0	COG0511@1|root,COG5016@1|root,COG0511@2|Bacteria,COG5016@2|Bacteria,1QTTG@1224|Proteobacteria,43BUE@68525|delta/epsilon subdivisions,2X75I@28221|Deltaproteobacteria,2MPKE@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Conserved carboxylase domain	oadA	-	2.1.3.1,4.1.1.3,6.4.1.1	ko:K01571,ko:K01960,ko:K03416	ko00020,ko00620,ko00640,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00640,map00720,map01100,map01120,map01200,map01230	M00173,M00620	R00217,R00344,R00353,R00930	RC00040,RC00097,RC00367	ko00000,ko00001,ko00002,ko01000,ko02000	3.B.1.1.1	-	-	Biotin_lipoyl,HMGL-like,PYC_OADA
k59_196868_1	335543.Sfum_0418	2.84e-67	209.0	COG1259@1|root,COG1259@2|Bacteria,1RFFV@1224|Proteobacteria,42SCI@68525|delta/epsilon subdivisions,2WPWT@28221|Deltaproteobacteria,2MQHM@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Bifunctional nuclease	-	-	-	ko:K08999	-	-	-	-	ko00000	-	-	-	DNase-RNase
k59_30228_1	1499967.BAYZ01000167_gene6742	7.08e-72	233.0	COG0747@1|root,COG0747@2|Bacteria	2|Bacteria	E	dipeptide transport	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
k59_22689_1	1304885.AUEY01000033_gene1894	3.92e-79	253.0	COG0664@1|root,COG0664@2|Bacteria,1RCF4@1224|Proteobacteria,43BRQ@68525|delta/epsilon subdivisions,2X72K@28221|Deltaproteobacteria,2MJHW@213118|Desulfobacterales	28221|Deltaproteobacteria	T	PFAM Cyclic nucleotide-binding	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388,cNMP_binding
k59_22689_2	933262.AXAM01000016_gene168	5.62e-13	66.6	COG1100@1|root,COG1100@2|Bacteria,1R6NS@1224|Proteobacteria,42NIX@68525|delta/epsilon subdivisions,2WJ44@28221|Deltaproteobacteria,2MI9K@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Gtr1/RagA G protein conserved region	mglA	GO:0008150,GO:0032879,GO:0032880,GO:0050789,GO:0065007	-	ko:K06883	-	-	-	-	ko00000	-	-	-	Arf
k59_196880_1	1121405.dsmv_0965	3.31e-121	369.0	COG0550@1|root,COG0550@2|Bacteria,1MUFZ@1224|Proteobacteria,42MM9@68525|delta/epsilon subdivisions,2WJTT@28221|Deltaproteobacteria,2MITA@213118|Desulfobacterales	28221|Deltaproteobacteria	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,zf-C4_Topoisom
k59_126668_2	1307759.JOMJ01000003_gene1875	5.66e-49	163.0	COG3271@1|root,COG3271@2|Bacteria,1RA3D@1224|Proteobacteria,42W4J@68525|delta/epsilon subdivisions,2WRJC@28221|Deltaproteobacteria,2MCIS@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Peptidase_C39 like family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C39_2
k59_27186_1	1121405.dsmv_2703	2.43e-79	247.0	COG0842@1|root,COG0842@2|Bacteria,1Q99P@1224|Proteobacteria,42M53@68525|delta/epsilon subdivisions,2WMEY@28221|Deltaproteobacteria,2MIY1@213118|Desulfobacterales	28221|Deltaproteobacteria	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane,ABC2_membrane_3
k59_81013_1	1265505.ATUG01000001_gene3485	3.32e-120	352.0	COG1638@1|root,COG1638@2|Bacteria,1MVYB@1224|Proteobacteria,42Q4E@68525|delta/epsilon subdivisions,2WKUU@28221|Deltaproteobacteria,2MK7S@213118|Desulfobacterales	28221|Deltaproteobacteria	G	Bacterial extracellular solute-binding protein, family 7	-	-	-	-	-	-	-	-	-	-	-	-	DctP
k59_194038_1	56780.SYN_02009	3.97e-46	155.0	COG2890@1|root,COG2890@2|Bacteria,1QUYS@1224|Proteobacteria,42UV8@68525|delta/epsilon subdivisions,2WQQU@28221|Deltaproteobacteria,2MRUR@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	Tellurite resistance protein TehB	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
k59_27188_1	1048834.TC41_1408	8.16e-11	67.4	COG1426@1|root,COG1426@2|Bacteria,1V1N7@1239|Firmicutes,4HKW3@91061|Bacilli	91061|Bacilli	S	Protein conserved in bacteria	ymfM	-	-	ko:K15539	-	-	-	-	ko00000	-	-	-	DUF4115,HTH_25
k59_163919_1	96561.Dole_2055	1.07e-11	65.9	COG4105@1|root,COG4105@2|Bacteria,1MVS5@1224|Proteobacteria,42RV8@68525|delta/epsilon subdivisions,2WKU0@28221|Deltaproteobacteria,2MJ58@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamD	-	-	ko:K05807	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	YfiO
k59_35585_1	1049564.TevJSym_af00930	7.38e-38	140.0	COG1639@1|root,COG2204@1|root,COG1639@2|Bacteria,COG2204@2|Bacteria,1RCW6@1224|Proteobacteria,1S3XV@1236|Gammaproteobacteria,1J6BK@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	T	HDOD domain	-	-	-	-	-	-	-	-	-	-	-	-	HDOD,Response_reg
k59_118217_1	314285.KT71_03162	8.51e-22	99.0	28HMZ@1|root,2Z7WD@2|Bacteria,1MU3Q@1224|Proteobacteria,1RRUM@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF3604)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3604
k59_27195_1	1454004.AW11_03649	2.34e-47	165.0	COG1253@1|root,COG1253@2|Bacteria,1MV3P@1224|Proteobacteria,2VHBA@28216|Betaproteobacteria	28216|Betaproteobacteria	S	CBS domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,DUF21
k59_141681_1	866536.Belba_0242	3.87e-09	66.6	COG0457@1|root,COG2885@1|root,COG0457@2|Bacteria,COG2885@2|Bacteria,4NE6G@976|Bacteroidetes,47MTM@768503|Cytophagia	976|Bacteroidetes	MU	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA,PD40,TPR_16,TPR_2,TPR_8
k59_111296_1	485916.Dtox_3052	3.62e-50	167.0	COG1456@1|root,COG1456@2|Bacteria,1VTSK@1239|Firmicutes,24XXV@186801|Clostridia,263UF@186807|Peptococcaceae	186801|Clostridia	C	CO dehydrogenase acetyl-CoA synthase gamma subunit (Corrinoid Fe-S protein)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3786,FeS
k59_81027_1	335543.Sfum_3079	4.46e-72	229.0	COG0620@1|root,COG0620@2|Bacteria,1R6KI@1224|Proteobacteria,42PCN@68525|delta/epsilon subdivisions,2WKT3@28221|Deltaproteobacteria,2MRM1@213462|Syntrophobacterales	28221|Deltaproteobacteria	E	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_42438_1	290397.Adeh_3905	3.1e-226	646.0	COG2225@1|root,COG2225@2|Bacteria,1MVEV@1224|Proteobacteria,42P3R@68525|delta/epsilon subdivisions,2X349@28221|Deltaproteobacteria,2YU6W@29|Myxococcales	28221|Deltaproteobacteria	H	Malate synthase	-	-	2.3.3.9	ko:K01638	ko00620,ko00630,ko01100,ko01110,ko01120,ko01200,map00620,map00630,map01100,map01110,map01120,map01200	M00012	R00472	RC00004,RC00308,RC02747	ko00000,ko00001,ko00002,ko01000	-	-	-	Malate_synthase
k59_50158_1	1125699.HMPREF9194_00894	0.000603	47.4	COG4856@1|root,COG4856@2|Bacteria,2J5XW@203691|Spirochaetes	203691|Spirochaetes	S	YbbR-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YbbR
k59_163944_1	485915.Dret_1795	4.98e-97	295.0	COG0475@1|root,COG0475@2|Bacteria,1RFKE@1224|Proteobacteria,43B2P@68525|delta/epsilon subdivisions,2X6GM@28221|Deltaproteobacteria,2M9P0@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	Sodium/hydrogen exchanger family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
k59_103750_2	1167006.UWK_03138	1.47e-16	75.9	COG3937@1|root,COG3937@2|Bacteria,1N4MU@1224|Proteobacteria,42UUE@68525|delta/epsilon subdivisions,2WQEZ@28221|Deltaproteobacteria,2MKJF@213118|Desulfobacterales	28221|Deltaproteobacteria	S	granule-associated protein	-	-	-	-	-	-	-	-	-	-	-	-	Phasin
k59_73411_1	258594.RPA1868	2.23e-55	179.0	COG2983@1|root,COG2983@2|Bacteria,1RHMX@1224|Proteobacteria,2U99S@28211|Alphaproteobacteria,3JR5E@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Belongs to the UPF0260 family	MA20_15575	-	-	ko:K09160	-	-	-	-	ko00000	-	-	-	CxxCxxCC
k59_35603_1	553174.HMPREF0659_A5455	1.41e-31	126.0	COG0128@1|root,COG0128@2|Bacteria,4NE8T@976|Bacteroidetes,2FNY8@200643|Bacteroidia	976|Bacteroidetes	E	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	aroA	-	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	EPSP_synthase
k59_35607_1	1121396.KB893084_gene407	4.59e-112	332.0	COG0683@1|root,COG0683@2|Bacteria,1MWQB@1224|Proteobacteria,42PN2@68525|delta/epsilon subdivisions,2WM53@28221|Deltaproteobacteria,2MKDA@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Receptor family ligand binding region	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
k59_239627_2	566466.NOR53_546	2.54e-71	218.0	COG1970@1|root,COG1970@2|Bacteria,1RHG8@1224|Proteobacteria,1S3PD@1236|Gammaproteobacteria,1JB6E@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell	mscL	GO:0003674,GO:0005215,GO:0005216,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015075,GO:0015267,GO:0015318,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022838,GO:0022857,GO:0030104,GO:0031224,GO:0031226,GO:0032535,GO:0034220,GO:0042592,GO:0042802,GO:0044425,GO:0044459,GO:0044464,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0071944,GO:0090066	-	ko:K03282	-	-	-	-	ko00000,ko02000	1.A.22.1	-	-	MscL
k59_50162_1	448385.sce0655	5.64e-08	57.4	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,42PPB@68525|delta/epsilon subdivisions,2X5YN@28221|Deltaproteobacteria,2YUEJ@29|Myxococcales	28221|Deltaproteobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_10,TPR_12
k59_50162_2	1380390.JIAT01000015_gene5810	2.39e-51	169.0	COG2050@1|root,COG2050@2|Bacteria,2IJ48@201174|Actinobacteria,4CQAC@84995|Rubrobacteria	84995|Rubrobacteria	Q	Domain of unknown function (DUF4442)	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
k59_50162_3	1121405.dsmv_0138	1.73e-46	154.0	COG0745@1|root,COG0745@2|Bacteria,1NBQZ@1224|Proteobacteria,42V8P@68525|delta/epsilon subdivisions,2WS87@28221|Deltaproteobacteria,2MN9A@213118|Desulfobacterales	28221|Deltaproteobacteria	KT	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
k59_187451_1	1291050.JAGE01000001_gene2182	1.13e-26	108.0	COG2801@1|root,COG2801@2|Bacteria,1V8EJ@1239|Firmicutes,24MA4@186801|Clostridia	186801|Clostridia	L	PFAM Integrase catalytic region	-	-	-	-	-	-	-	-	-	-	-	-	HTH_29,HTH_8,rve
k59_178979_1	96561.Dole_0142	1.31e-49	167.0	COG0012@1|root,COG0012@2|Bacteria,1MVM4@1224|Proteobacteria,42MNJ@68525|delta/epsilon subdivisions,2WIZZ@28221|Deltaproteobacteria,2MI8E@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Protein of unknown function (DUF933)	-	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
k59_217176_1	1198449.ACAM_1383	9.36e-61	206.0	COG2511@1|root,arCOG01719@2157|Archaea,2XPPH@28889|Crenarchaeota	28889|Crenarchaeota	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate	gatE	GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564	6.3.5.7	ko:K03330	ko00970,ko01100,map00970,map01100	-	R03905	RC00010	ko00000,ko00001,ko01000	-	-	-	GAD,GatB_N,GatB_Yqey
k59_134203_1	1121918.ARWE01000001_gene1602	2.51e-83	248.0	COG4564@1|root,COG4564@2|Bacteria,1N7NM@1224|Proteobacteria,42W17@68525|delta/epsilon subdivisions,2WRGB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	PFAM Cache	-	-	-	-	-	-	-	-	-	-	-	-	dCache_2,sCache_2
k59_42498_2	596151.DesfrDRAFT_1898	1.81e-46	152.0	COG0425@1|root,COG0425@2|Bacteria,1MZA5@1224|Proteobacteria,42VCF@68525|delta/epsilon subdivisions,2WRI6@28221|Deltaproteobacteria,2ME7G@213115|Desulfovibrionales	28221|Deltaproteobacteria	O	Belongs to the sulfur carrier protein TusA family	-	-	-	ko:K04085	ko04122,map04122	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	TusA
k59_134217_1	1123504.JQKD01000008_gene5435	5.17e-79	248.0	COG1413@1|root,COG1413@2|Bacteria,1NUN2@1224|Proteobacteria,2VMQF@28216|Betaproteobacteria,4ADK1@80864|Comamonadaceae	28216|Betaproteobacteria	C	lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
k59_239639_1	1232437.KL661988_gene276	2.3e-49	167.0	COG0589@1|root,COG0745@1|root,COG0589@2|Bacteria,COG0745@2|Bacteria,1MZPD@1224|Proteobacteria,42U2Y@68525|delta/epsilon subdivisions,2WQ1I@28221|Deltaproteobacteria,2MQ25@213118|Desulfobacterales	28221|Deltaproteobacteria	KT	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Usp
k59_27724_1	706587.Desti_1836	1.36e-96	293.0	COG1541@1|root,COG1541@2|Bacteria,1MXF5@1224|Proteobacteria,42MZA@68525|delta/epsilon subdivisions,2WIUC@28221|Deltaproteobacteria,2MRDJ@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)	paaK-3	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C_2
k59_65783_1	765910.MARPU_06455	5.06e-06	55.1	COG0642@1|root,COG3614@1|root,COG0642@2|Bacteria,COG2205@2|Bacteria,COG3614@2|Bacteria,1NRP8@1224|Proteobacteria,1SKTW@1236|Gammaproteobacteria,1WY3Z@135613|Chromatiales	135613|Chromatiales	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,HATPase_c,HisKA,Hpt,PAS_3,Response_reg
k59_111676_1	555779.Dthio_PD1478	2.24e-57	190.0	COG3547@1|root,COG3547@2|Bacteria,1MUER@1224|Proteobacteria,42WT2@68525|delta/epsilon subdivisions,2WR9X@28221|Deltaproteobacteria,2MAU1@213115|Desulfovibrionales	28221|Deltaproteobacteria	L	PFAM transposase IS116 IS110 IS902 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_240125_1	880072.Desac_0827	1.67e-123	369.0	COG0784@1|root,COG5002@1|root,COG0784@2|Bacteria,COG5002@2|Bacteria,1NC9X@1224|Proteobacteria,43DC7@68525|delta/epsilon subdivisions,2X8I7@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_9,Response_reg
k59_27733_1	1380390.JIAT01000017_gene5296	5.77e-49	174.0	COG1459@1|root,COG1459@2|Bacteria,2GQW0@201174|Actinobacteria,4CPUI@84995|Rubrobacteria	84995|Rubrobacteria	NU	COG COG1459 Type II secretory pathway component PulF Cell motility and secretion Intracellular trafficking and secretion	-	-	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
k59_157267_1	257310.BB0784	5.94e-16	82.8	COG1450@1|root,COG1450@2|Bacteria,1MVNC@1224|Proteobacteria,2VMZA@28216|Betaproteobacteria	28216|Betaproteobacteria	NU	type II and III secretion system protein	-	-	-	ko:K02453,ko:K12282	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	STN,Secretin,Secretin_N_2
k59_240127_1	883.DvMF_0487	4.71e-120	354.0	COG0462@1|root,COG0462@2|Bacteria,1MW21@1224|Proteobacteria,42MI2@68525|delta/epsilon subdivisions,2WJ5W@28221|Deltaproteobacteria,2M99U@213115|Desulfovibrionales	28221|Deltaproteobacteria	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	prs	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2848	Pribosyl_synth,Pribosyltran_N
k59_194523_2	1335230.S5VZM6_9CAUD	1.64e-24	94.4	4QAVS@10239|Viruses,4QX2I@35237|dsDNA viruses  no RNA stage,4QR41@28883|Caudovirales,4QIEF@10662|Myoviridae	10662|Myoviridae	S	Protein of unknown function (DUF2829)	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_50643_1	933262.AXAM01000016_gene149	1.85e-83	268.0	COG5009@1|root,COG5009@2|Bacteria,1MU5A@1224|Proteobacteria,42MJB@68525|delta/epsilon subdivisions,2WIXF@28221|Deltaproteobacteria,2MI9W@213118|Desulfobacterales	28221|Deltaproteobacteria	M	TIGRFAM penicillin-binding protein, 1A family	mrcA	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	iAF987.Gmet_0354	PCB_OB,Transgly,Transpeptidase
k59_88799_1	290318.Cvib_0103	2.63e-39	138.0	COG2801@1|root,COG2801@2|Bacteria	2|Bacteria	L	transposition	-	-	-	-	-	-	-	-	-	-	-	-	HTH_21,HTH_32,rve,rve_3
k59_217672_1	335543.Sfum_0605	1.05e-109	333.0	COG0029@1|root,COG0029@2|Bacteria,1RBQW@1224|Proteobacteria,43BKD@68525|delta/epsilon subdivisions,2WJNK@28221|Deltaproteobacteria,2MR7G@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	Catalyzes the oxidation of L-aspartate to iminoaspartate	nadB	-	1.4.3.16	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	M00115	R00357,R00481	RC00006,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
k59_88800_1	1121447.JONL01000002_gene1997	1.9e-87	276.0	COG0823@1|root,COG0823@2|Bacteria,1NR8W@1224|Proteobacteria,42YPB@68525|delta/epsilon subdivisions,2WTWD@28221|Deltaproteobacteria,2MAN0@213115|Desulfovibrionales	28221|Deltaproteobacteria	U	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	PD40
k59_13558_2	1121033.AUCF01000012_gene853	4.61e-31	121.0	COG0028@1|root,COG0028@2|Bacteria,1MX3Q@1224|Proteobacteria,2U2RW@28211|Alphaproteobacteria,2JVNM@204441|Rhodospirillales	204441|Rhodospirillales	EH	Thiamine pyrophosphate enzyme, central domain	-	-	-	-	-	-	-	-	-	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
k59_104279_1	1198232.CYCME_2142	1.61e-28	114.0	COG0642@1|root,COG2199@1|root,COG2205@2|Bacteria,COG3706@2|Bacteria,1NRP8@1224|Proteobacteria,1S5BV@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,HATPase_c,HisKA,MASE1
k59_65807_1	398767.Glov_0905	4.53e-17	81.6	COG0477@1|root,COG2814@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	yhjX	-	-	ko:K08177,ko:K18326	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.1.11,2.A.1.3.26	-	-	MFS_1
k59_164386_1	941449.dsx2_0448	3.03e-09	60.8	COG0484@1|root,COG0484@2|Bacteria,1R20J@1224|Proteobacteria,43DCY@68525|delta/epsilon subdivisions,2X8IV@28221|Deltaproteobacteria	2|Bacteria	O	PFAM Cytochrome c, class III, conserved region	-	-	-	ko:K03686,ko:K04082,ko:K05516	-	-	-	-	ko00000,ko03029,ko03036,ko03110	-	-	-	Cytochrom_CIII,Cytochrom_c3_2,DnaJ_C,DnaJ_CXXCXGXG
k59_225045_1	525909.Afer_0528	8.42e-17	84.3	COG0084@1|root,COG0084@2|Bacteria,2GMJJ@201174|Actinobacteria,4CN2X@84992|Acidimicrobiia	84992|Acidimicrobiia	L	TatD related DNase	-	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
k59_104287_1	756067.MicvaDRAFT_1931	1.35e-36	144.0	COG0642@1|root,COG0745@1|root,COG2770@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria,COG2770@2|Bacteria,1G09B@1117|Cyanobacteria,1H7M4@1150|Oscillatoriales	1117|Cyanobacteria	T	Signal transduction histidine kinase, subgroup 1, dimerisation phosphoacceptor domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HAMP,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg,dCache_1
k59_73875_1	706587.Desti_2952	1.29e-98	306.0	COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,42MQS@68525|delta/epsilon subdivisions,2WINP@28221|Deltaproteobacteria,2MR0I@213462|Syntrophobacterales	28221|Deltaproteobacteria	I	PFAM Enoyl-CoA hydratase isomerase	-	-	1.1.1.35,4.2.1.17,5.1.2.3,5.3.3.8	ko:K01782,ko:K01825	ko00071,ko00280,ko00281,ko00310,ko00362,ko00380,ko00410,ko00640,ko00650,ko00903,ko00930,ko01040,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00071,map00280,map00281,map00310,map00362,map00380,map00410,map00640,map00650,map00903,map00930,map01040,map01100,map01110,map01120,map01130,map01200,map01212	M00032,M00087	R01975,R03026,R03045,R03276,R04137,R04170,R04203,R04204,R04224,R04737,R04738,R04739,R04740,R04741,R04744,R04745,R04746,R04748,R04749,R04756,R05066,R05305,R06411,R06412,R06941,R06942,R07935,R07951,R08093,R08094	RC00029,RC00099,RC00117,RC00241,RC00525,RC00831,RC00834,RC00896,RC01078,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	3HCDH,3HCDH_N,ECH_1
k59_149055_1	1123284.KB899045_gene2502	1.36e-15	79.3	COG1360@1|root,COG1360@2|Bacteria,1V8KE@1239|Firmicutes,4H9MD@91061|Bacilli,26NZW@186821|Sporolactobacillaceae	91061|Bacilli	N	OmpA family	ytxE	-	-	ko:K02557	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	MotB_plug,OmpA
k59_104290_1	1121403.AUCV01000016_gene4416	3.61e-37	131.0	COG0834@1|root,COG0834@2|Bacteria,1RHMR@1224|Proteobacteria,42TGV@68525|delta/epsilon subdivisions,2WQZJ@28221|Deltaproteobacteria,2MKSF@213118|Desulfobacterales	28221|Deltaproteobacteria	ET	ABC-type amino acid transport signal transduction systems periplasmic component domain	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_164394_1	880072.Desac_0436	8.71e-48	173.0	COG0574@1|root,COG3848@1|root,COG0574@2|Bacteria,COG3848@2|Bacteria,1QFX3@1224|Proteobacteria,42PIP@68525|delta/epsilon subdivisions,2WKWI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	PFAM pyruvate phosphate dikinase, PEP pyruvate-binding	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PPDK_N
k59_174939_1	1265505.ATUG01000002_gene1747	4.27e-94	283.0	COG4177@1|root,COG4177@2|Bacteria,1MU52@1224|Proteobacteria,42RI3@68525|delta/epsilon subdivisions,2WNVC@28221|Deltaproteobacteria,2MJX3@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Branched-chain amino acid transport system / permease component	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
k59_53589_1	768706.Desor_5448	4.15e-19	88.2	COG2199@1|root,COG2206@1|root,COG2199@2|Bacteria,COG2206@2|Bacteria,1V6WM@1239|Firmicutes,25E5R@186801|Clostridia,2603J@186807|Peptococcaceae	186801|Clostridia	T	diguanylate cyclase (GGDEF) domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,HD,HD_5,PAS_9
k59_197672_1	768710.DesyoDRAFT_1842	1.81e-07	56.2	COG3335@1|root,COG3415@1|root,COG3335@2|Bacteria,COG3415@2|Bacteria,1V41H@1239|Firmicutes,24J23@186801|Clostridia	186801|Clostridia	L	Transposase and inactivated derivatives-like protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,HTH_29,HTH_32,HTH_33
k59_182431_1	1121012.AUKX01000002_gene3413	4.3e-123	363.0	COG2801@1|root,COG2801@2|Bacteria,4NHJD@976|Bacteroidetes,1IABF@117743|Flavobacteriia	976|Bacteroidetes	L	COG2801 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	HTH_29,rve,rve_3
k59_182432_1	633131.TR2A62_0118	8.29e-19	88.2	COG0559@1|root,COG0559@2|Bacteria,1MU25@1224|Proteobacteria,2TSZP@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01997,ko:K11956	ko02010,ko02024,map02010,map02024	M00237,M00322	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4,3.A.1.4.2,3.A.1.4.6	-	-	BPD_transp_2
k59_182432_2	1232437.KL662012_gene1400	2.82e-45	152.0	COG0410@1|root,COG0410@2|Bacteria,1MVVC@1224|Proteobacteria,42YP9@68525|delta/epsilon subdivisions,2WTKT@28221|Deltaproteobacteria,2MN4Y@213118|Desulfobacterales	28221|Deltaproteobacteria	E	ABC transporter	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
k59_99045_1	338963.Pcar_1695	2.86e-58	196.0	COG0084@1|root,COG0535@1|root,COG0084@2|Bacteria,COG0535@2|Bacteria,1MUC0@1224|Proteobacteria,42MMS@68525|delta/epsilon subdivisions,2WMUI@28221|Deltaproteobacteria,43S50@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	TatD related DNase	tatD	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	Fer4_14,Radical_SAM,TatD_DNase
k59_30837_1	742817.HMPREF9449_01416	1.67e-13	72.0	COG1213@1|root,COG1213@2|Bacteria,4NH70@976|Bacteroidetes,2FP2J@200643|Bacteroidia,22XH9@171551|Porphyromonadaceae	976|Bacteroidetes	M	Nucleotidyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_3,NTP_transferase
k59_159805_1	880072.Desac_0718	1.37e-62	207.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WJ88@28221|Deltaproteobacteria,2MRG9@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	two component, sigma54 specific, transcriptional regulator, Fis family	ntrX	-	-	ko:K13599	ko02020,map02020	M00498	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
k59_106693_1	882.DVU_0571	4.41e-85	263.0	COG0686@1|root,COG0686@2|Bacteria,1QTX1@1224|Proteobacteria,42MSF@68525|delta/epsilon subdivisions,2WKJ5@28221|Deltaproteobacteria,2M87G@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	Belongs to the AlaDH PNT family	ald	-	1.4.1.1	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	-	R00396	RC00008	ko00000,ko00001,ko01000	-	-	iAF987.Gmet_1099	AlaDh_PNT_C,AlaDh_PNT_N
k59_91443_1	883.DvMF_1570	3.78e-69	216.0	COG0765@1|root,COG0765@2|Bacteria,1QSE9@1224|Proteobacteria,42PC3@68525|delta/epsilon subdivisions,2WIMY@28221|Deltaproteobacteria,2MAQF@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	amino acid ABC transporter	-	-	-	ko:K02029	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	BPD_transp_1
k59_23295_1	1232437.KL661985_gene3578	4.83e-30	124.0	COG0457@1|root,COG0501@1|root,COG0457@2|Bacteria,COG0501@2|Bacteria,1R5A7@1224|Proteobacteria,42MP6@68525|delta/epsilon subdivisions,2WK92@28221|Deltaproteobacteria,2MIHI@213118|Desulfobacterales	28221|Deltaproteobacteria	O	PFAM peptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48,TPR_11,TPR_17
k59_23295_2	96561.Dole_1180	3.93e-32	116.0	COG1636@1|root,COG1636@2|Bacteria,1MUG5@1224|Proteobacteria,42M1E@68525|delta/epsilon subdivisions,2WMR5@28221|Deltaproteobacteria,2MJG7@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)	queH	-	1.17.99.6	ko:K09765	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF208
k59_15677_1	1499967.BAYZ01000171_gene5604	7.93e-86	265.0	COG1470@1|root,COG1470@2|Bacteria	2|Bacteria	S	cell adhesion involved in biofilm formation	-	-	3.2.1.22	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	-	R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091	RC00049,RC00059,RC00451	ko00000,ko00001,ko01000	-	-	-	Melibiase_2,NPCBM,NPCBM_assoc
k59_227913_1	1121405.dsmv_1447	4e-61	193.0	COG1014@1|root,COG1014@2|Bacteria,1R92Y@1224|Proteobacteria,42QJI@68525|delta/epsilon subdivisions,2WMFZ@28221|Deltaproteobacteria,2MJ4M@213118|Desulfobacterales	28221|Deltaproteobacteria	C	TIGRFAM 2-oxoacid acceptor oxidoreductase, gamma subunit, pyruvate 2-ketoisovalerate family	-	-	1.2.7.3	ko:K00177	ko00020,ko00720,ko01100,ko01120,ko01200,map00020,map00720,map01100,map01120,map01200	M00009,M00011,M00173,M00620	R01197	RC00004,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	POR
k59_152156_1	941449.dsx2_3189	1.34e-106	312.0	COG2009@1|root,2ZBTX@2|Bacteria,1RB22@1224|Proteobacteria,42NAY@68525|delta/epsilon subdivisions,2WMPM@28221|Deltaproteobacteria,2M7WC@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	PFAM fumarate reductase respiratory complex	-	-	-	ko:K00246	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	M00009,M00011,M00150,M00173	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	Sdh_cyt
k59_152156_2	485915.Dret_1066	7.01e-80	254.0	COG1053@1|root,COG1053@2|Bacteria,1MU5M@1224|Proteobacteria,42M81@68525|delta/epsilon subdivisions,2WJXY@28221|Deltaproteobacteria,2M826@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	TIGRFAM succinate dehydrogenase or fumarate reductase, flavoprotein subunit	sdhA	-	1.3.5.1,1.3.5.4	ko:K00239,ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,ko05134,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020,map05134	M00009,M00011,M00149,M00150,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
k59_197688_1	1123274.KB899414_gene3684	1.02e-47	165.0	COG1639@1|root,COG1639@2|Bacteria,2J74B@203691|Spirochaetes	203691|Spirochaetes	T	HDOD domain	-	-	-	-	-	-	-	-	-	-	-	-	HDOD
k59_167233_1	1121403.AUCV01000002_gene519	1.59e-168	479.0	COG1883@1|root,COG1883@2|Bacteria,1MV0G@1224|Proteobacteria,42MH1@68525|delta/epsilon subdivisions,2WJD7@28221|Deltaproteobacteria,2MIY0@213118|Desulfobacterales	28221|Deltaproteobacteria	C	TIGRFAM sodium ion-translocating decarboxylase, beta subunit	-	-	4.1.1.3	ko:K01572	ko00620,ko01100,map00620,map01100	-	R00217	RC00040	ko00000,ko00001,ko01000,ko02000	3.B.1.1.1	-	-	OAD_beta
k59_121860_1	316067.Geob_2698	9.22e-64	209.0	COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,42P7N@68525|delta/epsilon subdivisions,2WJKE@28221|Deltaproteobacteria,43TZJ@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	PFAM peptidase M16 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
k59_137030_1	1127673.GLIP_1795	2.83e-12	73.2	COG2304@1|root,COG3419@1|root,COG2304@2|Bacteria,COG3419@2|Bacteria,1NUAV@1224|Proteobacteria,1RPV3@1236|Gammaproteobacteria,46578@72275|Alteromonadaceae	1236|Gammaproteobacteria	NU	Tfp pilus assembly protein tip-associated adhesin	pilY1	-	-	ko:K02674	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	Neisseria_PilC,VWA_2
k59_152166_1	1121396.KB892935_gene3839	4.91e-89	273.0	COG0535@1|root,COG0535@2|Bacteria,1R5RB@1224|Proteobacteria,42NU3@68525|delta/epsilon subdivisions,2WJ27@28221|Deltaproteobacteria,2MJDN@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Iron-sulfur cluster-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Fer4_14,Radical_SAM,SPASM
k59_205334_1	338966.Ppro_1321	4.32e-40	141.0	COG3267@1|root,COG3267@2|Bacteria,1Q4DA@1224|Proteobacteria,42YYB@68525|delta/epsilon subdivisions,2WU9J@28221|Deltaproteobacteria	28221|Deltaproteobacteria	U	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22
k59_205334_2	177437.HRM2_44660	5.15e-47	164.0	COG2801@1|root,COG2801@2|Bacteria,1MUSB@1224|Proteobacteria,43AFH@68525|delta/epsilon subdivisions,2X5V7@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	PFAM Integrase catalytic region	-	-	-	-	-	-	-	-	-	-	-	-	rve
k59_182468_1	871963.Desdi_1557	1.9e-26	101.0	COG0494@1|root,COG0494@2|Bacteria,1V6ET@1239|Firmicutes,25EBI@186801|Clostridia,267A9@186807|Peptococcaceae	186801|Clostridia	L	Belongs to the Nudix hydrolase family	mutT	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
k59_23321_1	335543.Sfum_1328	1.11e-19	89.7	COG1453@1|root,COG1453@2|Bacteria,1RAU3@1224|Proteobacteria,43A0M@68525|delta/epsilon subdivisions,2X9UN@28221|Deltaproteobacteria,2MS7U@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	PFAM aldo keto reductase	-	-	-	ko:K07079	-	-	-	-	ko00000	-	-	-	Aldo_ket_red
k59_235605_1	1265505.ATUG01000003_gene52	3.61e-75	232.0	COG0204@1|root,COG0204@2|Bacteria,1MY51@1224|Proteobacteria,42QIX@68525|delta/epsilon subdivisions,2WJHE@28221|Deltaproteobacteria,2MIMI@213118|Desulfobacterales	28221|Deltaproteobacteria	I	Phosphate acyltransferases	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
k59_68832_1	1232437.KL662011_gene1495	3.49e-105	322.0	28J96@1|root,2Z947@2|Bacteria,1R6TE@1224|Proteobacteria,42PZG@68525|delta/epsilon subdivisions,2WIKY@28221|Deltaproteobacteria,2MHY0@213118|Desulfobacterales	28221|Deltaproteobacteria	S	PFAM Oligopeptide transporter OPT superfamily	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_68834_1	509190.Cseg_2754	2.88e-106	313.0	COG0451@1|root,COG0451@2|Bacteria,1MXKV@1224|Proteobacteria,2TRM0@28211|Alphaproteobacteria,2KF4B@204458|Caulobacterales	204458|Caulobacterales	GM	Dehydratase	-	-	4.1.1.35	ko:K08678	ko00520,ko01100,map00520,map01100	M00361	R01384	RC00508	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
k59_23323_2	96561.Dole_2313	1.2e-14	80.1	COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,42MEA@68525|delta/epsilon subdivisions,2WIW6@28221|Deltaproteobacteria,2MI74@213118|Desulfobacterales	28221|Deltaproteobacteria	KT	Sigma-54 interaction domain	-	-	2.1.1.80	ko:K00575	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	HTH_8,PAS_4,PAS_9,Sigma54_activat
k59_106723_1	439235.Dalk_0743	6.68e-63	209.0	COG0457@1|root,COG0457@2|Bacteria,1R64F@1224|Proteobacteria,42Q6D@68525|delta/epsilon subdivisions,2WKT0@28221|Deltaproteobacteria,2MHV1@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4388)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388
k59_227933_1	765869.BDW_00880	1.86e-51	180.0	COG0568@1|root,COG0568@2|Bacteria,1MVNJ@1224|Proteobacteria,42N2S@68525|delta/epsilon subdivisions,2MST9@213481|Bdellovibrionales,2WJ0E@28221|Deltaproteobacteria	213481|Bdellovibrionales	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	rpoD	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_ner,Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
k59_152184_1	1121405.dsmv_1536	3.94e-75	231.0	COG0664@1|root,COG0664@2|Bacteria,1MZZD@1224|Proteobacteria,42QUX@68525|delta/epsilon subdivisions,2WMWV@28221|Deltaproteobacteria,2MJH7@213118|Desulfobacterales	28221|Deltaproteobacteria	K	cyclic nucleotide-binding	fnr-1	-	-	ko:K01420,ko:K21563	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
k59_23327_1	96561.Dole_1417	1.34e-127	383.0	COG0247@1|root,COG0247@2|Bacteria,1MUMH@1224|Proteobacteria,42MIV@68525|delta/epsilon subdivisions,2WJ5X@28221|Deltaproteobacteria,2MIC5@213118|Desulfobacterales	28221|Deltaproteobacteria	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_8,Fer4_9
k59_137049_1	272556.CF65_00263	9.99e-47	166.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,1RMWA@1236|Gammaproteobacteria,1Y7XU@135625|Pasteurellales	135625|Pasteurellales	JKL	DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA	rhlB	GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360	3.6.4.13	ko:K03732	ko03018,map03018	M00394	-	-	ko00000,ko00001,ko00002,ko01000,ko03019	-	-	-	DEAD,Helicase_C
k59_61392_1	439235.Dalk_5215	6.69e-159	455.0	COG1158@1|root,COG1158@2|Bacteria,1MUCF@1224|Proteobacteria,42M15@68525|delta/epsilon subdivisions,2WIQN@28221|Deltaproteobacteria,2MI44@213118|Desulfobacterales	28221|Deltaproteobacteria	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
k59_535_1	153721.MYP_4752	2.23e-13	77.0	COG0437@1|root,COG0437@2|Bacteria,4NE5M@976|Bacteroidetes,47NK7@768503|Cytophagia	976|Bacteroidetes	C	4Fe-4S dicluster domain	nrfC	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_7,Molydop_binding
k59_91483_1	203119.Cthe_2755	2.32e-70	220.0	COG1397@1|root,COG1397@2|Bacteria,1TQPF@1239|Firmicutes,24AQ2@186801|Clostridia,3WHM0@541000|Ruminococcaceae	186801|Clostridia	O	ADP-ribosylglycohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	ADP_ribosyl_GH
k59_91483_2	937774.TEQUI_0251	1.73e-13	68.9	COG4974@1|root,COG4974@2|Bacteria,1MVNF@1224|Proteobacteria,2VIHD@28216|Betaproteobacteria,3T1RX@506|Alcaligenaceae	28216|Betaproteobacteria	D	recombinase XerD	xerD	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
k59_220561_1	1121405.dsmv_3585	1.64e-48	155.0	COG0185@1|root,COG0185@2|Bacteria,1RGYX@1224|Proteobacteria,42THY@68525|delta/epsilon subdivisions,2WQ0F@28221|Deltaproteobacteria,2MKPD@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA	rpsS	GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904	-	ko:K02965	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S19
k59_137059_1	1121405.dsmv_0333	8.59e-106	319.0	COG1055@1|root,COG1055@2|Bacteria,1QUC0@1224|Proteobacteria,42NUZ@68525|delta/epsilon subdivisions,2WJNH@28221|Deltaproteobacteria,2MPNS@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Sodium:sulfate symporter transmembrane region	-	-	-	ko:K14445	-	-	-	-	ko00000,ko02000	2.A.47.1	-	-	Na_sulph_symp
k59_541_1	1237149.C900_04195	1.49e-51	174.0	COG0382@1|root,COG0382@2|Bacteria,4NIRK@976|Bacteroidetes,47SWZ@768503|Cytophagia	976|Bacteroidetes	H	UbiA prenyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	UbiA
k59_159868_1	335543.Sfum_1225	1.19e-96	315.0	COG0587@1|root,COG0587@2|Bacteria,1MUIF@1224|Proteobacteria,42MGP@68525|delta/epsilon subdivisions,2WIZ2@28221|Deltaproteobacteria,2MQUW@213462|Syntrophobacterales	28221|Deltaproteobacteria	L	DNA polymerase III alpha subunit	dnaE	-	2.7.7.7	ko:K02337,ko:K14162	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
k59_559_1	429009.Adeg_1078	1.69e-130	397.0	COG1148@1|root,COG1908@1|root,COG1148@2|Bacteria,COG1908@2|Bacteria,1UT78@1239|Firmicutes,24A6H@186801|Clostridia,42FPJ@68295|Thermoanaerobacterales	186801|Clostridia	C	PFAM methyl-viologen-reducing hydrogenase delta subunit	-	-	-	ko:K16886	-	-	-	-	ko00000	-	-	-	Fer4,Fer4_9,FlpD,Pyr_redox_2
k59_38558_1	1121405.dsmv_0071	2.31e-86	267.0	COG1249@1|root,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,42N8Y@68525|delta/epsilon subdivisions,2WIR7@28221|Deltaproteobacteria,2MHP6@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM Pyridine nucleotide-disulphide oxidoreductase, FAD NAD(P)-binding domain, pyridine nucleotide-disulfide oxidoreductase dimerization region, FAD-dependent pyridine nucleotide-disulfide oxidoreductase	lpdA-1	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
k59_129443_1	795359.TOPB45_0885	1.6e-12	66.2	COG0374@1|root,COG0374@2|Bacteria,2GH4N@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	C	Nickel-dependent hydrogenase	-	-	1.12.99.6	ko:K06281	ko00633,ko01120,map00633,map01120	-	R08034	RC00250	ko00000,ko00001,ko01000	-	-	-	NiFeSe_Hases
k59_129443_2	439235.Dalk_2275	3.73e-70	219.0	COG1740@1|root,COG1740@2|Bacteria,1MWAC@1224|Proteobacteria,42MI0@68525|delta/epsilon subdivisions,2WIW4@28221|Deltaproteobacteria,2MJ8Z@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Hydrogenase (NiFe) small subunit HydA	hydA	GO:0005575,GO:0005623,GO:0042597,GO:0044464	1.12.2.1,1.12.5.1,1.12.7.2,1.12.99.6	ko:K00534,ko:K05927,ko:K06282,ko:K18008	ko00633,ko01120,map00633,map01120	-	R00019,R08034	RC00250	ko00000,ko00001,ko01000	-	-	-	NiFe_hyd_SSU_C,Oxidored_q6,TAT_signal
k59_152205_1	331869.BAL199_13523	1.13e-16	80.9	COG0779@1|root,COG0779@2|Bacteria,1RDP2@1224|Proteobacteria,2TS4E@28211|Alphaproteobacteria,4BQU4@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	J	Required for maturation of 30S ribosomal subunits	rimP	GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576	-	ko:K09748	-	-	-	-	ko00000,ko03009	-	-	-	DUF150,DUF150_C
k59_152205_2	1121405.dsmv_2731	4.26e-28	112.0	COG0195@1|root,COG0195@2|Bacteria,1MWT7@1224|Proteobacteria,42MUW@68525|delta/epsilon subdivisions,2WIXI@28221|Deltaproteobacteria,2MHW6@213118|Desulfobacterales	28221|Deltaproteobacteria	K	Participates in both transcription termination and antitermination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	HHH_5,KH_5,NusA_N,S1
k59_23339_1	1220534.B655_0809	1.94e-45	157.0	COG0524@1|root,arCOG00014@2157|Archaea,2XU7Z@28890|Euryarchaeota,23NZS@183925|Methanobacteria	183925|Methanobacteria	G	Belongs to the carbohydrate kinase PfkB family	-	-	2.7.1.15	ko:K00852	ko00030,map00030	-	R01051,R02750	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
k59_23339_2	868131.MSWAN_0958	3.95e-21	90.9	COG2037@1|root,arCOG02695@2157|Archaea,2XUV2@28890|Euryarchaeota,23NJN@183925|Methanobacteria	183925|Methanobacteria	C	Formylmethanofuran-tetrahydromethanopterin formyltransferase	ftr1	-	2.3.1.101	ko:K00672	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00567	R03390	RC00197,RC00870,RC02881	ko00000,ko00001,ko00002,ko01000	-	-	-	FTR,FTR_C
k59_159876_1	933262.AXAM01000005_gene2473	2.17e-69	223.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42PZ5@68525|delta/epsilon subdivisions,2WM1A@28221|Deltaproteobacteria,2MJZM@213118|Desulfobacterales	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,PocR,Response_reg,SBP_bac_3,sCache_2
k59_167277_1	1121405.dsmv_3642	8.03e-79	237.0	COG0049@1|root,COG0049@2|Bacteria,1MXC8@1224|Proteobacteria,42QR7@68525|delta/epsilon subdivisions,2WNFM@28221|Deltaproteobacteria,2MJJG@213118|Desulfobacterales	28221|Deltaproteobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA	rpsG	GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02992	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S7
k59_23340_1	335543.Sfum_1954	5.11e-77	253.0	COG1034@1|root,COG1034@2|Bacteria,1P8MN@1224|Proteobacteria,42PT5@68525|delta/epsilon subdivisions,2WIPN@28221|Deltaproteobacteria,2MR73@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	TIGRFAM NADH-quinone oxidoreductase, chain G	nuoG-2	-	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
k59_106746_1	335543.Sfum_0798	1.62e-71	231.0	COG1193@1|root,COG1193@2|Bacteria,1NCS6@1224|Proteobacteria,42VGJ@68525|delta/epsilon subdivisions,2WRA6@28221|Deltaproteobacteria,2MS78@213462|Syntrophobacterales	28221|Deltaproteobacteria	L	PFAM Smr protein MutS2	-	-	-	-	-	-	-	-	-	-	-	-	Smr
k59_46062_1	880072.Desac_1971	9.04e-55	181.0	COG1899@1|root,COG1899@2|Bacteria,1R3WQ@1224|Proteobacteria,42M57@68525|delta/epsilon subdivisions,2WJ6N@28221|Deltaproteobacteria,2MREK@213462|Syntrophobacterales	28221|Deltaproteobacteria	O	peptidyl-lysine modification to peptidyl-hypusine	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_152216_1	96561.Dole_1461	1.32e-101	313.0	COG0369@1|root,COG1151@2|Bacteria,1NYH2@1224|Proteobacteria,42NE1@68525|delta/epsilon subdivisions,2WIVX@28221|Deltaproteobacteria,2MINQ@213118|Desulfobacterales	28221|Deltaproteobacteria	C	TIGRFAM carbon-monoxide dehydrogenase, catalytic subunit	-	-	1.2.7.4	ko:K00198	ko00633,ko00680,ko00720,ko01120,ko01200,map00633,map00680,map00720,map01120,map01200	M00377	R07157,R08034	RC00250,RC02800	ko00000,ko00001,ko00002,ko01000	-	-	-	Prismane
k59_30886_1	1121405.dsmv_1757	1.54e-104	310.0	COG0351@1|root,COG0351@2|Bacteria,1MU9J@1224|Proteobacteria,42N1F@68525|delta/epsilon subdivisions,2WK2V@28221|Deltaproteobacteria,2MI0R@213118|Desulfobacterales	28221|Deltaproteobacteria	H	PFAM Phosphomethylpyrimidine kinase	thiD	-	2.5.1.3,2.7.1.49,2.7.4.7	ko:K00941,ko:K14153,ko:K21219	ko00730,ko01100,map00730,map01100	M00127	R03223,R03471,R04509,R10712	RC00002,RC00017,RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2909	Phos_pyr_kin,TMP-TENI,ThiP_synth
k59_30886_2	886379.AEWI01000002_gene464	4.46e-47	157.0	COG2206@1|root,COG2206@2|Bacteria,4PKEV@976|Bacteroidetes,2G3ER@200643|Bacteroidia,3XK10@558415|Marinilabiliaceae	976|Bacteroidetes	T	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	ko:K06950	-	-	-	-	ko00000	-	-	-	HD
k59_152220_1	1121405.dsmv_1650	1.48e-50	178.0	COG0633@1|root,COG3894@1|root,COG0633@2|Bacteria,COG3894@2|Bacteria,1MV6C@1224|Proteobacteria,42MF5@68525|delta/epsilon subdivisions,2WIJD@28221|Deltaproteobacteria,2MHUT@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Domain of unknown function (DUF4445)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4445,Fer2
k59_175010_1	1232437.KL662006_gene4388	4.41e-71	218.0	2C477@1|root,32RDF@2|Bacteria,1RKW1@1224|Proteobacteria,42SWN@68525|delta/epsilon subdivisions,2WP88@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	DGC domain	-	-	-	-	-	-	-	-	-	-	-	-	DGC
k59_46657_1	1121405.dsmv_1695	1.53e-40	142.0	COG3640@1|root,COG3640@2|Bacteria,1RB02@1224|Proteobacteria,42NBP@68525|delta/epsilon subdivisions,2WKS7@28221|Deltaproteobacteria,2MJA2@213118|Desulfobacterales	28221|Deltaproteobacteria	D	PFAM Cobyrinic acid ac-diamide synthase	cooC	-	-	ko:K07321	-	-	-	-	ko00000	-	-	-	CbiA
k59_46657_2	2423.NA23_0200640	1.14e-25	102.0	COG1469@1|root,COG1469@2|Bacteria,2GC82@200918|Thermotogae	200918|Thermotogae	F	Converts GTP to 7,8-dihydroneopterin triphosphate	folE2	-	3.5.4.16	ko:K09007	ko00790,ko01100,map00790,map01100	M00126	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	GCHY-1
k59_175569_2	754476.Q7A_1879	1.76e-23	93.6	COG1848@1|root,COG1848@2|Bacteria,1RFD9@1224|Proteobacteria,1S6PP@1236|Gammaproteobacteria,463AW@72273|Thiotrichales	72273|Thiotrichales	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
k59_167825_1	1416760.AYMS01000107_gene88	3.12e-43	158.0	COG3385@1|root,COG3385@2|Bacteria,4NXT2@976|Bacteroidetes	976|Bacteroidetes	L	hmm pf01609	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_4
k59_236283_1	177437.HRM2_37620	1.28e-41	156.0	COG1643@1|root,COG1643@2|Bacteria,1MUEQ@1224|Proteobacteria,42MD4@68525|delta/epsilon subdivisions,2WJ7Z@28221|Deltaproteobacteria,2MIAK@213118|Desulfobacterales	28221|Deltaproteobacteria	L	TIGRFAM ATP-dependent helicase HrpA	hrpA	-	3.6.4.13	ko:K03578,ko:K03579	-	-	-	-	ko00000,ko01000	-	-	-	AAA_19,DEAD,DUF3418,HA2,Helicase_C,OB_NTP_bind
k59_175570_1	292564.Cyagr_1734	5.62e-46	158.0	COG1064@1|root,COG1064@2|Bacteria,1G0B9@1117|Cyanobacteria	1117|Cyanobacteria	C	alcohol dehydrogenase	-	-	-	ko:K12957	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
k59_175572_1	251229.Chro_4009	1.72e-07	57.0	COG0842@1|root,COG1131@1|root,COG1716@1|root,COG0842@2|Bacteria,COG1131@2|Bacteria,COG1716@2|Bacteria,1G102@1117|Cyanobacteria,3VI20@52604|Pleurocapsales	1117|Cyanobacteria	V	ABC-type multidrug transport system ATPase component	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane,ABC_tran,FHA
k59_239876_1	177437.HRM2_07790	1.07e-83	263.0	COG0471@1|root,COG0471@2|Bacteria,1MUSA@1224|Proteobacteria,42MAP@68525|delta/epsilon subdivisions,2WIYI@28221|Deltaproteobacteria,2MJA8@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Sodium:sulfate symporter transmembrane region	sdcS	-	-	ko:K14445	-	-	-	-	ko00000,ko02000	2.A.47.1	-	-	Na_sulph_symp
k59_224778_1	1232437.KL662064_gene4024	7.43e-48	173.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42NFY@68525|delta/epsilon subdivisions,2WKC0@28221|Deltaproteobacteria,2MI11@213118|Desulfobacterales	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	2.7.13.3	ko:K10819	-	-	-	-	ko00000,ko01000	-	-	-	HATPase_c,HisKA,PAS_8,PAS_9,sCache_3_2
k59_141982_1	398580.Dshi_0642	1.24e-25	107.0	COG0530@1|root,COG0530@2|Bacteria,1MU3R@1224|Proteobacteria,2TST5@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	COG0530 Ca2 Na antiporter	-	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
k59_210250_1	933262.AXAM01000036_gene2181	2.45e-82	271.0	COG1197@1|root,COG1197@2|Bacteria,1MUXG@1224|Proteobacteria,42N8X@68525|delta/epsilon subdivisions,2WIVR@28221|Deltaproteobacteria,2MI3P@213118|Desulfobacterales	28221|Deltaproteobacteria	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
k59_104001_1	1121405.dsmv_2598	1.37e-194	556.0	COG0595@1|root,COG0595@2|Bacteria,1MUGV@1224|Proteobacteria,42M65@68525|delta/epsilon subdivisions,2WIQ9@28221|Deltaproteobacteria,2MHNU@213118|Desulfobacterales	28221|Deltaproteobacteria	S	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay	rnj	-	-	ko:K12574	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	Lactamase_B,Lactamase_B_2,RMMBL
k59_239889_1	1304885.AUEY01000005_gene842	2.33e-86	270.0	COG1008@1|root,COG1008@2|Bacteria,1MV7V@1224|Proteobacteria,42NGD@68525|delta/epsilon subdivisions,2WJDC@28221|Deltaproteobacteria,2MJG3@213118|Desulfobacterales	28221|Deltaproteobacteria	C	TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M	nuoM	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q5_N,Proton_antipo_M
k59_13258_1	935948.KE386494_gene504	1.18e-66	213.0	COG1924@1|root,COG1924@2|Bacteria,1TPU5@1239|Firmicutes,2481F@186801|Clostridia,42FAJ@68295|Thermoanaerobacterales	186801|Clostridia	I	ATPase BadF BadG BcrA BcrD type	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG
k59_239891_1	1327982.R9ZYM1_9CAUD	1.42e-71	220.0	4QD0J@10239|Viruses,4R0A5@35237|dsDNA viruses  no RNA stage,4QSK9@28883|Caudovirales	28883|Caudovirales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_179180_1	335543.Sfum_1424	1.25e-48	169.0	COG0172@1|root,COG0172@2|Bacteria,1MUJF@1224|Proteobacteria,42M7H@68525|delta/epsilon subdivisions,2WIT7@28221|Deltaproteobacteria,2MQ90@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iAF987.Gmet_3528	Seryl_tRNA_N,tRNA-synt_2b
k59_118512_1	933262.AXAM01000001_gene422	3.88e-37	127.0	COG0762@1|root,COG0762@2|Bacteria,1QDB9@1224|Proteobacteria,42VCU@68525|delta/epsilon subdivisions,2WRHX@28221|Deltaproteobacteria,2MKPA@213118|Desulfobacterales	28221|Deltaproteobacteria	S	YGGT family	-	-	-	ko:K02221	-	-	-	-	ko00000,ko02044	-	-	-	YGGT
k59_148726_2	589865.DaAHT2_2278	6.78e-45	166.0	COG3419@1|root,COG3419@2|Bacteria,1NUAV@1224|Proteobacteria,42NJ7@68525|delta/epsilon subdivisions,2WJYB@28221|Deltaproteobacteria,2MPX7@213118|Desulfobacterales	28221|Deltaproteobacteria	NU	Tfp pilus assembly protein tip-associated adhesin	-	-	-	ko:K02674	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	Neisseria_PilC
k59_58720_1	138119.DSY0349	3.76e-35	134.0	COG1680@1|root,COG1680@2|Bacteria,1TR9E@1239|Firmicutes,2480P@186801|Clostridia,265WQ@186807|Peptococcaceae	186801|Clostridia	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
k59_142000_1	192875.XP_004365086.1	8.74e-07	57.0	COG0417@1|root,KOG0969@2759|Eukaryota,38DSD@33154|Opisthokonta	33154|Opisthokonta	L	DNA replication proofreading	POLD1	GO:0000109,GO:0000228,GO:0000278,GO:0000723,GO:0000731,GO:0000781,GO:0000784,GO:0003674,GO:0003676,GO:0003677,GO:0003682,GO:0003684,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005657,GO:0005694,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006278,GO:0006281,GO:0006283,GO:0006284,GO:0006287,GO:0006289,GO:0006296,GO:0006297,GO:0006301,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007049,GO:0008150,GO:0008152,GO:0008296,GO:0008408,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009987,GO:0016043,GO:0016070,GO:0016234,GO:0016235,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0018130,GO:0019438,GO:0019439,GO:0019725,GO:0019899,GO:0019985,GO:0022402,GO:0022616,GO:0030894,GO:0031974,GO:0031981,GO:0032200,GO:0032201,GO:0032991,GO:0032993,GO:0033260,GO:0033554,GO:0033567,GO:0033683,GO:0034061,GO:0034641,GO:0034644,GO:0034645,GO:0034654,GO:0034655,GO:0042575,GO:0042592,GO:0042769,GO:0043137,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043596,GO:0043601,GO:0043625,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044271,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044444,GO:0044446,GO:0044454,GO:0044464,GO:0044786,GO:0045004,GO:0045005,GO:0046483,GO:0046700,GO:0048878,GO:0050801,GO:0050896,GO:0051276,GO:0051606,GO:0051716,GO:0055081,GO:0055088,GO:0055089,GO:0060249,GO:0061695,GO:0065007,GO:0065008,GO:0070013,GO:0070914,GO:0071214,GO:0071478,GO:0071482,GO:0071704,GO:0071840,GO:0071897,GO:0090304,GO:0090305,GO:0097159,GO:0098687,GO:0104004,GO:0140097,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901575,GO:1901576,GO:1902296,GO:1902319,GO:1902494,GO:1902969,GO:1902983,GO:1903047,GO:1903459,GO:1904161,GO:1990234,GO:1990391	2.7.7.7	ko:K02327	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03430,ko03440,ko05166,map00230,map00240,map01100,map03030,map03410,map03420,map03430,map03440,map05166	M00262	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol_B,DNA_pol_B_exo1,zf-C4pol
k59_20187_1	1121403.AUCV01000004_gene2076	8.4e-18	91.3	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42PE6@68525|delta/epsilon subdivisions,2X5DJ@28221|Deltaproteobacteria,2MMJA@213118|Desulfobacterales	28221|Deltaproteobacteria	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal,dCache_1
k59_217398_1	335543.Sfum_3027	7.7e-46	158.0	COG0688@1|root,COG0688@2|Bacteria,1MW45@1224|Proteobacteria,42QDS@68525|delta/epsilon subdivisions,2WMQ3@28221|Deltaproteobacteria,2MQID@213462|Syntrophobacterales	28221|Deltaproteobacteria	I	Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)	psd	-	4.1.1.65	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	M00093	R02055	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	PS_Dcarbxylase
k59_202578_1	335543.Sfum_3063	1.57e-114	343.0	COG0793@1|root,COG0793@2|Bacteria,1MU39@1224|Proteobacteria,42MHD@68525|delta/epsilon subdivisions,2WJKC@28221|Deltaproteobacteria,2MQ40@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	PDZ domain (Also known as DHR or GLGF)	ctpA	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_S41
k59_210277_1	1121405.dsmv_1666	2.23e-109	343.0	COG0243@1|root,COG0437@1|root,COG0243@2|Bacteria,COG0437@2|Bacteria,1MU1B@1224|Proteobacteria,42NEG@68525|delta/epsilon subdivisions,2WKHA@28221|Deltaproteobacteria,2MMPS@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	actB	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_7,Molybdop_Fe4S4,Molybdopterin,Molydop_binding
k59_20196_1	485913.Krac_11000	5.73e-29	116.0	COG1609@1|root,COG1609@2|Bacteria	2|Bacteria	K	purine nucleotide biosynthetic process	-	-	5.3.1.12	ko:K01812,ko:K02529,ko:K16210	ko00040,ko01100,map00040,map01100	M00061,M00631	R01482,R01983	RC00376	ko00000,ko00001,ko00002,ko01000,ko02000,ko03000	2.A.2.5	-	-	DDE_Tnp_ISAZ013,Peripla_BP_3
k59_96324_2	1232437.KL662013_gene1341	2.23e-38	139.0	COG1597@1|root,COG1597@2|Bacteria,1RCJT@1224|Proteobacteria,42W6W@68525|delta/epsilon subdivisions	1224|Proteobacteria	I	Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
k59_13281_1	469381.Dpep_1453	3.85e-45	157.0	COG0739@1|root,COG0739@2|Bacteria,3TAYS@508458|Synergistetes	508458|Synergistetes	M	Peptidase, M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
k59_13281_2	999141.GME_09616	1.04e-09	57.4	COG1722@1|root,COG1722@2|Bacteria,1N72V@1224|Proteobacteria,1SC7N@1236|Gammaproteobacteria,1XMTV@135619|Oceanospirillales	135619|Oceanospirillales	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseB	-	3.1.11.6	ko:K03602	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_S
k59_13281_3	1123070.KB899259_gene2021	1.09e-15	76.6	COG0142@1|root,COG0142@2|Bacteria,46S62@74201|Verrucomicrobia,2IU28@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	Polyprenyl synthetase	-	-	2.5.1.1,2.5.1.10,2.5.1.29	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00366	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
k59_27453_1	177437.HRM2_31140	1.76e-66	220.0	COG0145@1|root,COG0145@2|Bacteria,1MU2Y@1224|Proteobacteria,42P6S@68525|delta/epsilon subdivisions,2WIWC@28221|Deltaproteobacteria,2MI1I@213118|Desulfobacterales	28221|Deltaproteobacteria	EQ	PFAM Hydantoinase oxoprolinase	-	-	-	-	-	-	-	-	-	-	-	-	Hydant_A_N,Hydantoinase_A
k59_148745_1	903814.ELI_3780	1.27e-22	93.6	COG5496@1|root,COG5496@2|Bacteria,1VAZJ@1239|Firmicutes,24MWR@186801|Clostridia,25WV6@186806|Eubacteriaceae	186801|Clostridia	S	THIoesterase	-	-	3.1.2.29	ko:K18700	-	-	-	-	ko00000,ko01000	-	-	-	4HBT
k59_148745_2	402880.MmarC5_1142	1.15e-06	48.9	COG0655@1|root,arCOG02573@2157|Archaea,2XWPJ@28890|Euryarchaeota	28890|Euryarchaeota	S	PFAM NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
k59_65515_1	1121423.JONT01000001_gene2152	1.47e-51	174.0	COG2896@1|root,COG2896@2|Bacteria,1TP89@1239|Firmicutes,247PP@186801|Clostridia,260P7@186807|Peptococcaceae	186801|Clostridia	H	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate	moaA	-	4.1.99.22	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394	RC03420	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Fer4_14,Mob_synth_C,Radical_SAM
k59_4433_1	237368.SCABRO_02100	9.21e-25	97.4	COG4276@1|root,COG4276@2|Bacteria,2J0FI@203682|Planctomycetes	203682|Planctomycetes	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc
k59_4433_2	945543.VIBR0546_20008	9.98e-35	123.0	COG1051@1|root,COG1051@2|Bacteria,1RF2T@1224|Proteobacteria,1S44A@1236|Gammaproteobacteria,1XXP0@135623|Vibrionales	135623|Vibrionales	F	Belongs to the Nudix hydrolase family	-	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
k59_233187_2	443152.MDG893_10246	4.62e-05	52.0	COG4254@1|root,COG4254@2|Bacteria,1NKA2@1224|Proteobacteria,1S1E7@1236|Gammaproteobacteria,46B8N@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	FecR,LysM
k59_217413_1	1454004.AW11_00535	4.59e-74	238.0	COG2267@1|root,COG2267@2|Bacteria,1QTZP@1224|Proteobacteria,2VKTF@28216|Betaproteobacteria	28216|Betaproteobacteria	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6,Hydrolase_4
k59_58749_1	1121405.dsmv_2992	3.33e-31	120.0	296GG@1|root,2ZTS1@2|Bacteria,1P6CJ@1224|Proteobacteria,4325G@68525|delta/epsilon subdivisions,2WXXV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_118539_1	933262.AXAM01000084_gene1045	5.68e-130	377.0	COG0463@1|root,COG0463@2|Bacteria	2|Bacteria	M	Glycosyl transferase, family 2	-	-	2.4.1.266	ko:K13693	-	-	-	-	ko00000,ko01000,ko01003	-	GT81	-	Glycos_transf_2
k59_217420_1	641491.DND132_2026	8.14e-35	130.0	COG4671@1|root,COG4671@2|Bacteria,1N1PQ@1224|Proteobacteria,42MDW@68525|delta/epsilon subdivisions,2WKQK@28221|Deltaproteobacteria,2M92X@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	PFAM Glycosyltransferase 28	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tran_28_C
k59_240505_1	1327981.R9ZYG2_9CAUD	2.68e-11	68.6	4QB5I@10239|Viruses,4QUT2@35237|dsDNA viruses  no RNA stage,4QPQ9@28883|Caudovirales,4QKRP@10699|Siphoviridae	10699|Siphoviridae	S	helicase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_13817_1	1121405.dsmv_3562	2.88e-25	101.0	COG0289@1|root,COG0289@2|Bacteria,1QB39@1224|Proteobacteria,42NRC@68525|delta/epsilon subdivisions,2WJGM@28221|Deltaproteobacteria,2MJ2I@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Belongs to the DapB family	-	-	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	-	DapB_C,DapB_N
k59_157467_1	1121405.dsmv_2904	1.15e-118	350.0	COG0138@1|root,COG0138@2|Bacteria,1MUDQ@1224|Proteobacteria,42MV4@68525|delta/epsilon subdivisions,2WKHZ@28221|Deltaproteobacteria,2MI2I@213118|Desulfobacterales	28221|Deltaproteobacteria	F	PFAM AICARFT IMPCHase bienzyme	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
k59_13820_1	696281.Desru_1453	4.2e-08	60.1	COG1566@1|root,COG1566@2|Bacteria,1UJ4C@1239|Firmicutes,25G1C@186801|Clostridia,267E1@186807|Peptococcaceae	186801|Clostridia	V	PFAM secretion protein HlyD family protein	-	-	-	ko:K01993,ko:K03543	-	M00701	-	-	ko00000,ko00002,ko02000	8.A.1.1	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
k59_164623_1	999141.GME_13808	2.59e-07	50.4	COG1886@1|root,COG1886@2|Bacteria,1RGWT@1224|Proteobacteria,1S5YE@1236|Gammaproteobacteria,1XJY8@135619|Oceanospirillales	135619|Oceanospirillales	N	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation	fliN	-	-	ko:K02417	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	FliMN_C
k59_164623_2	933262.AXAM01000005_gene2514	3.61e-20	86.7	2DF9M@1|root,2ZR0E@2|Bacteria	2|Bacteria	N	Flagellar biosynthesis protein, FliO	-	-	-	-	-	-	-	-	-	-	-	-	FliO
k59_112082_1	1121405.dsmv_3476	1.83e-107	333.0	COG0495@1|root,COG0495@2|Bacteria,1MV47@1224|Proteobacteria,42MRQ@68525|delta/epsilon subdivisions,2WJ3E@28221|Deltaproteobacteria,2MJ6A@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	iAF987.Gmet_2300	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
k59_203100_1	234267.Acid_0127	1.69e-35	134.0	COG1102@1|root,COG1102@2|Bacteria	2|Bacteria	F	Psort location Cytoplasmic, score	-	-	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Cytidylate_kin2,GAF_2,Pribosyltran
k59_43175_1	335543.Sfum_0820	2.28e-17	78.6	COG1150@1|root,COG1150@2|Bacteria,1RHH3@1224|Proteobacteria,42SBS@68525|delta/epsilon subdivisions,2WPKY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	4Fe-4S dicluster domain	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03390,ko:K16887	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4_17,Fer4_9
k59_43175_2	555779.Dthio_PD2367	3.86e-59	198.0	COG2048@1|root,COG2048@2|Bacteria,1N37J@1224|Proteobacteria,42P51@68525|delta/epsilon subdivisions,2WK1J@28221|Deltaproteobacteria,2M7RR@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	heterodisulfide reductase	hdrB	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03389	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	CCG
k59_43175_3	764298.STRMA_1271	1.56e-08	56.6	COG1309@1|root,COG1309@2|Bacteria,1VB5A@1239|Firmicutes	1239|Firmicutes	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
k59_142579_1	331678.Cphamn1_0514	1.62e-48	177.0	COG2931@1|root,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	HemolysinCabind
k59_104489_1	1232410.KI421420_gene3227	1.38e-86	281.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2WJ8D@28221|Deltaproteobacteria,43U53@69541|Desulfuromonadales	28221|Deltaproteobacteria	V	AcrB/AcrD/AcrF family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran,OEP
k59_59244_1	1121405.dsmv_2932	5.63e-119	349.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,42MK5@68525|delta/epsilon subdivisions,2WJ3Z@28221|Deltaproteobacteria,2MIA8@213118|Desulfobacterales	28221|Deltaproteobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
k59_13834_1	1121405.dsmv_1271	5.5e-68	218.0	COG0589@1|root,COG0589@2|Bacteria,1NY54@1224|Proteobacteria	1224|Proteobacteria	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
k59_36348_1	743299.Acife_0020	1.84e-18	90.1	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RRXX@1236|Gammaproteobacteria,2NBWM@225057|Acidithiobacillales	225057|Acidithiobacillales	T	Bacterial regulatory protein, Fis family	-	-	-	ko:K13599	ko02020,map02020	M00498	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
k59_194791_1	1278073.MYSTI_07288	4.1e-42	154.0	COG0492@1|root,COG3437@1|root,COG0492@2|Bacteria,COG3437@2|Bacteria,1MV15@1224|Proteobacteria,42MHR@68525|delta/epsilon subdivisions,2WIY8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,cNMP_binding
k59_96792_1	1121405.dsmv_0326	2.92e-97	290.0	COG1192@1|root,COG1192@2|Bacteria,1MV43@1224|Proteobacteria,42MTF@68525|delta/epsilon subdivisions,2WJ6X@28221|Deltaproteobacteria,2MHMY@213118|Desulfobacterales	28221|Deltaproteobacteria	D	PFAM CobQ CobB MinD ParA nucleotide binding domain	soj	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
k59_157476_1	1121405.dsmv_0507	3.55e-79	250.0	COG2204@1|root,COG2204@2|Bacteria,1PAPS@1224|Proteobacteria,42YHK@68525|delta/epsilon subdivisions,2WUDF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Bacterial regulatory protein, Fis family	-	-	-	ko:K07713	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
k59_179687_1	1232436.CAPF01000008_gene1786	0.000196	48.1	COG0834@1|root,COG0834@2|Bacteria,2GJQW@201174|Actinobacteria,4CVTJ@84998|Coriobacteriia	84998|Coriobacteriia	ET	PFAM extracellular solute-binding protein family 3	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
k59_210813_1	118161.KB235919_gene6402	4.22e-101	312.0	2DMFF@1|root,32R5F@2|Bacteria,1GAQC@1117|Cyanobacteria	1117|Cyanobacteria	S	IMG reference gene	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_194794_1	330214.NIDE2408	1.1e-24	109.0	COG3206@1|root,COG3206@2|Bacteria	2|Bacteria	M	extracellular polysaccharide biosynthetic process	-	-	-	ko:K07011,ko:K16706	-	-	-	-	ko00000	-	-	-	GNVR,Wzz
k59_217949_1	1116472.MGMO_17c00060	1.12e-34	138.0	COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,1RMHY@1236|Gammaproteobacteria,1XEIK@135618|Methylococcales	135618|Methylococcales	KT	PFAM RNA polymerase sigma factor 54, interaction	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,PAS_4,Sigma54_activat
k59_13843_1	1121405.dsmv_3781	7.92e-92	280.0	COG5421@1|root,COG5421@2|Bacteria,1R3NX@1224|Proteobacteria,42QDV@68525|delta/epsilon subdivisions,2WIRQ@28221|Deltaproteobacteria,2MN1S@213118|Desulfobacterales	68525|delta/epsilon subdivisions	L	PFAM transposase IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
k59_89152_1	1123242.JH636437_gene6066	9.47e-13	72.8	COG0859@1|root,COG0859@2|Bacteria,2IYZS@203682|Planctomycetes	203682|Planctomycetes	M	COG0859 ADP-heptose LPS heptosyltransferase	-	-	-	ko:K02841,ko:K02849	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
k59_194798_1	1280953.HOC_16990	1.21e-38	141.0	COG3039@1|root,COG3039@2|Bacteria,1MUVI@1224|Proteobacteria,2TSA7@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_6,DUF772
k59_194798_2	525897.Dbac_2569	4.84e-06	47.4	COG0399@1|root,COG0399@2|Bacteria,1N0QW@1224|Proteobacteria,42W70@68525|delta/epsilon subdivisions,2X245@28221|Deltaproteobacteria,2MFSC@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
k59_104503_1	1232410.KI421422_gene2087	6.97e-09	58.9	COG0589@1|root,COG0589@2|Bacteria,1RA7K@1224|Proteobacteria,42V2P@68525|delta/epsilon subdivisions,2WRFB@28221|Deltaproteobacteria,43UR0@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
k59_104503_2	522772.Dacet_1218	6.11e-20	89.7	COG4666@1|root,COG4666@2|Bacteria,2GEUP@200930|Deferribacteres	200930|Deferribacteres	S	transport system permease	-	-	-	-	-	-	-	-	-	-	-	-	DUF3394,DctM
k59_233743_1	1117108.PAALTS15_21533	6.21e-17	80.1	COG1932@1|root,COG1932@2|Bacteria,1TP6Y@1239|Firmicutes,4HATT@91061|Bacilli,26SI9@186822|Paenibacillaceae	91061|Bacilli	E	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine	serC	GO:0003674,GO:0003824,GO:0004648,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006563,GO:0006564,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.6.1.52	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	M00020,M00124	R04173,R05085	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
k59_233743_2	96561.Dole_2074	1.32e-29	115.0	COG1350@1|root,COG1350@2|Bacteria,1N07Y@1224|Proteobacteria,42MPB@68525|delta/epsilon subdivisions,2WJUV@28221|Deltaproteobacteria,2MJ5P@213118|Desulfobacterales	28221|Deltaproteobacteria	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB2	-	4.2.1.20	ko:K06001	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
k59_13849_1	1121405.dsmv_3084	1.01e-32	127.0	COG0477@1|root,COG2814@2|Bacteria,1R842@1224|Proteobacteria,42QBY@68525|delta/epsilon subdivisions,2WKB6@28221|Deltaproteobacteria,2MHNH@213118|Desulfobacterales	28221|Deltaproteobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
k59_13849_2	335543.Sfum_0813	4.98e-80	253.0	COG0624@1|root,COG0624@2|Bacteria,1MW20@1224|Proteobacteria,42N09@68525|delta/epsilon subdivisions,2WIRX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Peptidase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
k59_210823_1	1232437.KL662020_gene769	1.17e-114	344.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,42M5F@68525|delta/epsilon subdivisions,2WISF@28221|Deltaproteobacteria,2MIAR@213118|Desulfobacterales	28221|Deltaproteobacteria	IQ	PFAM AMP-dependent synthetase and ligase	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
k59_172553_1	1089551.KE386572_gene1293	7.94e-43	150.0	COG1192@1|root,COG1192@2|Bacteria,1MV43@1224|Proteobacteria,2TSWH@28211|Alphaproteobacteria,4BPR9@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	D	PFAM CobQ CobB MinD ParA nucleotide binding domain	parA	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
k59_43193_1	96561.Dole_0013	8.01e-30	118.0	COG0064@1|root,COG0064@2|Bacteria,1MUKG@1224|Proteobacteria,42M31@68525|delta/epsilon subdivisions,2WJK4@28221|Deltaproteobacteria,2MIIZ@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
k59_59255_1	1125863.JAFN01000001_gene613	1.69e-101	309.0	COG0677@1|root,COG0677@2|Bacteria,1MUC6@1224|Proteobacteria,42M4F@68525|delta/epsilon subdivisions,2WKK3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM UDP-glucose GDP-mannose dehydrogenase	-	-	1.1.1.136	ko:K02474,ko:K13015	ko00520,map00520	-	R00421,R06894	RC00291	ko00000,ko00001,ko01000,ko01005	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
k59_10489_1	999541.bgla_1g13630	1.51e-13	73.6	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2VJP6@28216|Betaproteobacteria,1K2AK@119060|Burkholderiaceae	28216|Betaproteobacteria	K	PFAM sigma-54 factor interaction domain-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Sigma54_activat
k59_70991_1	933262.AXAM01000009_gene1495	2.44e-59	196.0	COG0141@1|root,COG0141@2|Bacteria,1MUUF@1224|Proteobacteria,42M3R@68525|delta/epsilon subdivisions,2WJGT@28221|Deltaproteobacteria,2MICP@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine	hisD	GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.23	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01158,R01163,R03012	RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000	-	-	-	Histidinol_dh
k59_131828_1	933262.AXAM01000100_gene3391	2.77e-115	358.0	COG0187@1|root,COG0187@2|Bacteria,1MVKT@1224|Proteobacteria,42M7M@68525|delta/epsilon subdivisions,2WJ9X@28221|Deltaproteobacteria,2MHSK@213118|Desulfobacterales	28221|Deltaproteobacteria	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
k59_238010_1	1167006.UWK_01245	4.44e-20	88.2	COG0648@1|root,COG0648@2|Bacteria,1MX4Y@1224|Proteobacteria,42MYE@68525|delta/epsilon subdivisions,2WJC7@28221|Deltaproteobacteria,2MIWS@213118|Desulfobacterales	28221|Deltaproteobacteria	L	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin	nfo	GO:0003674,GO:0003824,GO:0003906,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008081,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360	3.1.21.2	ko:K01151	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AP_endonuc_2
k59_238010_2	1304874.JAFY01000002_gene661	1.01e-132	389.0	COG0477@1|root,COG2814@2|Bacteria,3TACG@508458|Synergistetes	508458|Synergistetes	EGP	PFAM Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
k59_56147_1	1201290.M902_0698	7.7e-13	69.3	2DPB2@1|root,331BY@2|Bacteria,1NBDA@1224|Proteobacteria,42VNW@68525|delta/epsilon subdivisions,2WSXY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_33132_1	933262.AXAM01000039_gene1162	1.29e-11	61.6	COG0359@1|root,COG0359@2|Bacteria,1RD0R@1224|Proteobacteria,42SCQ@68525|delta/epsilon subdivisions,2WPZQ@28221|Deltaproteobacteria,2MJFS@213118|Desulfobacterales	28221|Deltaproteobacteria	J	binds to the 23S rRNA	rplI	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02939	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L9_C,Ribosomal_L9_N
k59_78874_1	192952.MM_1893	2.03e-183	520.0	COG0641@1|root,arCOG00945@2157|Archaea,2Y0F7@28890|Euryarchaeota,2NAGD@224756|Methanomicrobia	224756|Methanomicrobia	K	SEC-C motif	-	-	-	ko:K06871	-	-	-	-	ko00000	-	-	-	Fer4_12,Radical_SAM,SEC-C,SPASM
k59_93874_1	1121468.AUBR01000020_gene2863	1.81e-52	174.0	COG0727@1|root,COG0727@2|Bacteria,1V2T2@1239|Firmicutes,24H4P@186801|Clostridia,42H0T@68295|Thermoanaerobacterales	186801|Clostridia	S	Putative zinc- or iron-chelating domain	-	-	-	ko:K06940	-	-	-	-	ko00000	-	-	-	CxxCxxCC
k59_48281_1	555779.Dthio_PD2818	1.05e-27	110.0	COG1433@1|root,COG1433@2|Bacteria,1N7IQ@1224|Proteobacteria,42WGA@68525|delta/epsilon subdivisions,2WS2U@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Dinitrogenase iron-molybdenum cofactor	-	-	-	-	-	-	-	-	-	-	-	-	Nitro_FeMo-Co
k59_222955_1	272558.10175997	3.39e-12	67.8	COG3551@1|root,COG3551@2|Bacteria,1UBXJ@1239|Firmicutes,4IND9@91061|Bacilli,1ZNAQ@1386|Bacillus	91061|Bacilli	S	Sulfotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_3
k59_222955_2	1415780.JPOG01000001_gene1011	8.93e-10	61.2	COG3119@1|root,COG3119@2|Bacteria,1NIZU@1224|Proteobacteria,1S0SZ@1236|Gammaproteobacteria,1X5WH@135614|Xanthomonadales	135614|Xanthomonadales	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
k59_230386_1	933262.AXAM01000048_gene2576	4.38e-22	99.8	COG0457@1|root,COG1944@1|root,COG0457@2|Bacteria,COG1944@2|Bacteria,1MV7K@1224|Proteobacteria,42N4B@68525|delta/epsilon subdivisions,2WJ34@28221|Deltaproteobacteria,2MHRU@213118|Desulfobacterales	28221|Deltaproteobacteria	S	YcaO cyclodehydratase, ATP-ad Mg2+-binding	-	-	-	ko:K09136	-	-	-	-	ko00000,ko03009	-	-	-	TPR_1,TPR_16,TPR_2,TPR_8,YcaO
k59_116329_1	314345.SPV1_09633	1.16e-14	80.1	COG1988@1|root,COG1988@2|Bacteria,1R5QP@1224|Proteobacteria	1224|Proteobacteria	S	membrane-bound metal-dependent	-	-	-	ko:K07038	-	-	-	-	ko00000	-	-	-	YdjM
k59_17913_1	935948.KE386494_gene211	3.68e-24	92.8	COG0694@1|root,COG0694@2|Bacteria,1VAAU@1239|Firmicutes,24R29@186801|Clostridia,42GUA@68295|Thermoanaerobacterales	186801|Clostridia	O	PFAM nitrogen-fixing NifU domain protein	-	-	-	-	-	-	-	-	-	-	-	-	NifU
k59_17913_2	269799.Gmet_3202	5.03e-34	124.0	COG1576@1|root,COG1576@2|Bacteria,1N7WB@1224|Proteobacteria,42V41@68525|delta/epsilon subdivisions,2X6IT@28221|Deltaproteobacteria,43UX0@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA	rlmH	-	2.1.1.177	ko:K00783	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SPOUT_MTase
k59_63624_1	1313304.CALK_1985	2.88e-42	154.0	COG1228@1|root,COG1228@2|Bacteria	2|Bacteria	Q	imidazolonepropionase activity	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
k59_116338_1	1293054.HSACCH_01202	3.3e-63	210.0	COG0168@1|root,COG0168@2|Bacteria,1TPAF@1239|Firmicutes,248K4@186801|Clostridia,3WB17@53433|Halanaerobiales	186801|Clostridia	P	PFAM Cation	trkH	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
k59_93882_1	880072.Desac_0177	2.19e-122	362.0	COG5621@1|root,COG5621@2|Bacteria,1MUVF@1224|Proteobacteria,42Q9D@68525|delta/epsilon subdivisions,2WK21@28221|Deltaproteobacteria,2MQ4M@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Lipocalin-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CrtC,Lipocalin_9
k59_215030_1	439235.Dalk_0268	6.61e-217	617.0	COG5421@1|root,COG5421@2|Bacteria,1R3NX@1224|Proteobacteria,42QDV@68525|delta/epsilon subdivisions,2WIRQ@28221|Deltaproteobacteria,2MN1S@213118|Desulfobacterales	28221|Deltaproteobacteria	L	PFAM transposase IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
k59_93883_1	880072.Desac_0122	3.06e-19	89.0	COG0767@1|root,COG0767@2|Bacteria,1N2HV@1224|Proteobacteria,42UV1@68525|delta/epsilon subdivisions,2WQXM@28221|Deltaproteobacteria	28221|Deltaproteobacteria	Q	COG0767 ABC-type transport system involved in resistance to organic solvents, permease component	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
k59_17926_2	565033.GACE_1810	1.29e-06	48.5	COG1656@1|root,arCOG04290@2157|Archaea,2XXTT@28890|Euryarchaeota,2468Z@183980|Archaeoglobi	183980|Archaeoglobi	S	Mut7-C RNAse domain	-	-	-	ko:K09122	-	-	-	-	ko00000	-	-	-	Mut7-C
k59_162175_1	269482.Bcep1808_1171	5.81e-18	88.2	28JKJ@1|root,2Z9DD@2|Bacteria,1MUN2@1224|Proteobacteria,2W6XZ@28216|Betaproteobacteria,1KD72@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Phage P22-like portal protein	-	-	-	-	-	-	-	-	-	-	-	-	P22_portal
k59_154755_1	177437.HRM2_39510	3.57e-116	348.0	COG4584@1|root,COG4584@2|Bacteria,1MWIV@1224|Proteobacteria,42SM4@68525|delta/epsilon subdivisions,2WPVD@28221|Deltaproteobacteria,2MNUX@213118|Desulfobacterales	28221|Deltaproteobacteria	L	PFAM Integrase catalytic region	-	-	-	-	-	-	-	-	-	-	-	-	rve
k59_131880_1	177437.HRM2_15120	4.65e-71	221.0	COG2010@1|root,COG2010@2|Bacteria,1P88Q@1224|Proteobacteria,43BRV@68525|delta/epsilon subdivisions,2X73R@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Cytochrome c7 and related cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_CIII,Cytochrome_C7
k59_131880_2	1121405.dsmv_1663	1.28e-55	188.0	COG5557@1|root,COG5557@2|Bacteria,1QURB@1224|Proteobacteria,43BT1@68525|delta/epsilon subdivisions,2X73S@28221|Deltaproteobacteria,2MMX3@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Pfam Polysulphide reductase, NrfD	actF	-	-	-	-	-	-	-	-	-	-	-	-
k59_185203_1	764298.STRMA_1131	3.39e-17	75.9	COG0776@1|root,COG0776@2|Bacteria,1V9XQ@1239|Firmicutes,4HKF2@91061|Bacilli	91061|Bacilli	L	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions	hup	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
k59_33165_1	880072.Desac_0826	8.08e-162	466.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	two component, sigma54 specific, transcriptional regulator, Fis family	-	-	-	ko:K07714	ko02020,map02020	M00500	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
k59_10509_1	744980.TRICHSKD4_6172	1.52e-50	182.0	COG4644@1|root,COG4644@2|Bacteria,1MUIU@1224|Proteobacteria,2UPXC@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	Tn3 transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_Tn3
k59_86114_1	1232437.KL662038_gene2303	1.07e-96	305.0	COG1067@1|root,COG1067@2|Bacteria,1MWGB@1224|Proteobacteria,42NJD@68525|delta/epsilon subdivisions,2WJFK@28221|Deltaproteobacteria,2MHNT@213118|Desulfobacterales	28221|Deltaproteobacteria	O	Belongs to the peptidase S16 family	-	-	3.4.21.53	ko:K01338,ko:K04076,ko:K04770	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA_32,Lon_C
k59_162181_1	401526.TcarDRAFT_1175	4.39e-37	138.0	COG0849@1|root,COG0849@2|Bacteria,1TQC5@1239|Firmicutes,4H1XB@909932|Negativicutes	909932|Negativicutes	D	MutL protein	-	-	-	-	-	-	-	-	-	-	-	-	MutL
k59_131881_1	1121405.dsmv_3621	1.85e-107	322.0	COG1052@1|root,COG1052@2|Bacteria,1MU2D@1224|Proteobacteria,42P72@68525|delta/epsilon subdivisions,2WKRS@28221|Deltaproteobacteria,2MJS8@213118|Desulfobacterales	28221|Deltaproteobacteria	C	D-isomer specific 2-hydroxyacid dehydrogenase	gyaR	-	1.1.1.26	ko:K00015,ko:K15893	ko00260,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,map00260,map00630,map01100,map01110,map01120,map01130,map01200	M00532	R00717,R01388	RC00031,RC00042	ko00000,ko00001,ko00002,ko01000	-	-	-	2-Hacid_dh,2-Hacid_dh_C
k59_2728_1	595460.RRSWK_03372	7.68e-78	268.0	COG2197@1|root,COG2909@1|root,COG2197@2|Bacteria,COG2909@2|Bacteria,2IZND@203682|Planctomycetes	203682|Planctomycetes	K	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
k59_192351_1	446468.Ndas_3326	1.42e-41	167.0	COG0209@1|root,COG1372@1|root,COG0209@2|Bacteria,COG1372@2|Bacteria,2I9SJ@201174|Actinobacteria,4EI6W@85012|Streptosporangiales	201174|Actinobacteria	FL	Intein splicing domain	-	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Intein_splicing,LAGLIDADG_3,Ribonuc_red_2_N,Ribonuc_red_lgC
k59_238037_1	1304874.JAFY01000002_gene834	8.94e-27	103.0	COG1720@1|root,COG1720@2|Bacteria,3TBKI@508458|Synergistetes	508458|Synergistetes	S	Uncharacterised protein family UPF0066	-	-	-	-	-	-	-	-	-	-	-	-	UPF0066
k59_185217_1	439235.Dalk_1211	2e-67	212.0	COG0330@1|root,COG0330@2|Bacteria,1MUM8@1224|Proteobacteria,42NX0@68525|delta/epsilon subdivisions,2WISZ@28221|Deltaproteobacteria,2MI3Y@213118|Desulfobacterales	28221|Deltaproteobacteria	O	PFAM band 7 protein	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
k59_3110_1	1196324.A374_03359	1.84e-71	230.0	COG1160@1|root,COG1160@2|Bacteria,1TPNM@1239|Firmicutes,4HAJ6@91061|Bacilli	91061|Bacilli	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	-	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
k59_64150_1	879212.DespoDRAFT_01413	6.17e-52	175.0	COG2853@1|root,COG2853@2|Bacteria,1MVX0@1224|Proteobacteria,42RII@68525|delta/epsilon subdivisions,2WNS9@28221|Deltaproteobacteria,2MJZ8@213118|Desulfobacterales	28221|Deltaproteobacteria	M	PFAM VacJ family lipoprotein	-	-	-	ko:K04754	-	-	-	-	ko00000	-	-	-	MlaA
k59_208490_1	1232437.KL661965_gene3270	1.56e-175	508.0	COG2414@1|root,COG2414@2|Bacteria,1MWBB@1224|Proteobacteria,42NR7@68525|delta/epsilon subdivisions,2WK49@28221|Deltaproteobacteria,2MJNF@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Aldehyde ferredoxin oxidoreductase	-	-	1.2.7.5	ko:K03738	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00309	R08571	RC00242	ko00000,ko00001,ko00002,ko01000	-	-	-	AFOR_C,AFOR_N
k59_11302_2	1357423.S5MB93_9CAUD	5.63e-25	108.0	4QAM2@10239|Viruses,4QV3W@35237|dsDNA viruses  no RNA stage,4QPGK@28883|Caudovirales,4QIRV@10662|Myoviridae	10662|Myoviridae	S	5'-3' exonuclease, N-terminal resolvase-like domain	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_125140_1	335543.Sfum_0306	1.23e-122	365.0	COG0119@1|root,COG0119@2|Bacteria,1MUNQ@1224|Proteobacteria,42MSP@68525|delta/epsilon subdivisions,2WIUZ@28221|Deltaproteobacteria,2MQXU@213462|Syntrophobacterales	28221|Deltaproteobacteria	E	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)	leuA	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
k59_162642_1	1123371.ATXH01000007_gene560	3.46e-123	374.0	COG0480@1|root,COG0480@2|Bacteria,2GH7F@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	J	Elongation factor G, domain IV	-	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU
k59_102305_1	497965.Cyan7822_3550	2.53e-24	105.0	COG0427@1|root,COG1670@1|root,COG0427@2|Bacteria,COG1670@2|Bacteria,1G2D3@1117|Cyanobacteria	1117|Cyanobacteria	CJ	TIGRFAM acetyl coenzyme A synthetase (ADP forming), alpha domain	-	-	-	-	-	-	-	-	-	-	-	-	AcetylCoA_hyd_C,AcetylCoA_hydro,Acetyltransf_1
k59_94506_1	1121405.dsmv_0063	4.64e-124	376.0	COG0045@1|root,COG1042@1|root,COG0045@2|Bacteria,COG1042@2|Bacteria,1MW98@1224|Proteobacteria,42KZW@68525|delta/epsilon subdivisions,2WIQB@28221|Deltaproteobacteria,2MITU@213118|Desulfobacterales	28221|Deltaproteobacteria	C	CoA binding domain	-	-	6.2.1.13	ko:K01905,ko:K22224	ko00010,ko00620,ko00640,ko01100,ko01120,map00010,map00620,map00640,map01100,map01120	-	R00229,R00920	RC00004,RC00012,RC00014	ko00000,ko00001,ko01000,ko01004	-	-	-	ATP-grasp_5,Acetyltransf_3,CoA_binding_2,Succ_CoA_lig
k59_192882_1	643562.Daes_3095	3.13e-54	183.0	COG3547@1|root,COG3547@2|Bacteria,1MUER@1224|Proteobacteria,42WT2@68525|delta/epsilon subdivisions,2WR9X@28221|Deltaproteobacteria,2MAU1@213115|Desulfovibrionales	28221|Deltaproteobacteria	L	PFAM transposase IS116 IS110 IS902 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_185902_1	1121405.dsmv_1515	4.6e-14	70.1	COG1595@1|root,COG1595@2|Bacteria,1N413@1224|Proteobacteria,42SGS@68525|delta/epsilon subdivisions,2WPQ9@28221|Deltaproteobacteria,2MKU0@213118|Desulfobacterales	28221|Deltaproteobacteria	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
k59_140194_1	1167006.UWK_00888	7.48e-12	66.6	COG0581@1|root,COG0581@2|Bacteria,1MUWB@1224|Proteobacteria,42MWK@68525|delta/epsilon subdivisions,2WJKH@28221|Deltaproteobacteria,2MJ8E@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Domain of unknown function (DUF3333)	pstA	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1,DUF3333
k59_140194_2	1121448.DGI_1886	1.35e-41	148.0	COG0573@1|root,COG0573@2|Bacteria,1MVKP@1224|Proteobacteria,42N2N@68525|delta/epsilon subdivisions,2WJJ1@28221|Deltaproteobacteria,2M8CM@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	probably responsible for the translocation of the substrate across the membrane	pstC	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1,DUF3708
k59_64157_1	1123234.AUKI01000003_gene172	9.72e-27	104.0	COG2963@1|root,COG2963@2|Bacteria,4NW8K@976|Bacteroidetes	2|Bacteria	L	Transposase	-	-	-	ko:K07483,ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_Tnp_1
k59_64157_2	655815.ZPR_4711	1e-39	147.0	COG2801@1|root,COG2801@2|Bacteria,4NRIR@976|Bacteroidetes,1I4VB@117743|Flavobacteriia	976|Bacteroidetes	L	Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	rve
k59_64157_3	643867.Ftrac_3626	3.21e-08	55.5	COG2909@1|root,COG2909@2|Bacteria,4PBPM@976|Bacteroidetes,47W4T@768503|Cytophagia	976|Bacteroidetes	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,TPR_12
k59_94510_1	1125863.JAFN01000001_gene1617	1.33e-61	209.0	COG1226@1|root,COG4651@1|root,COG1226@2|Bacteria,COG4651@2|Bacteria,1MV34@1224|Proteobacteria,42MEM@68525|delta/epsilon subdivisions,2WK23@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family	-	-	-	ko:K03455,ko:K11747	-	-	-	-	ko00000,ko02000	2.A.37,2.A.37.1.2	-	-	Na_H_Exchanger,TrkA_C,TrkA_N
k59_33917_2	439235.Dalk_1678	4.37e-74	229.0	COG0425@1|root,COG0425@2|Bacteria,1N08X@1224|Proteobacteria,42RUG@68525|delta/epsilon subdivisions,2WNNK@28221|Deltaproteobacteria,2MJVC@213118|Desulfobacterales	28221|Deltaproteobacteria	O	Belongs to the sulfur carrier protein TusA family	yedF	-	-	-	-	-	-	-	-	-	-	-	DrsE,TusA
k59_132539_2	1121406.JAEX01000018_gene2816	3.55e-67	219.0	COG0472@1|root,COG0472@2|Bacteria,1MWYW@1224|Proteobacteria,42NVY@68525|delta/epsilon subdivisions,2X5IH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Glycosyl transferase family 4	-	-	2.7.8.33,2.7.8.35	ko:K02851	-	-	R08856	RC00002	ko00000,ko01000,ko01003,ko01005	-	-	-	CoA_binding_3,Glycos_transf_4
k59_86725_1	335543.Sfum_0057	4.05e-45	155.0	COG0253@1|root,COG0253@2|Bacteria,1MWDH@1224|Proteobacteria,42MRX@68525|delta/epsilon subdivisions,2WMP4@28221|Deltaproteobacteria,2MQD5@213462|Syntrophobacterales	28221|Deltaproteobacteria	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	dapF	-	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	DAP_epimerase
k59_185906_1	933262.AXAM01000014_gene231	2.99e-57	185.0	COG2159@1|root,COG2159@2|Bacteria,1RJPH@1224|Proteobacteria,42T4E@68525|delta/epsilon subdivisions,2WPSE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
k59_192883_1	585502.HMPREF0645_2349	1.82e-111	341.0	COG0657@1|root,COG0657@2|Bacteria	2|Bacteria	I	acetylesterase activity	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3,Lipase_GDSL_2
k59_196491_1	316067.Geob_0994	1.51e-39	147.0	COG3344@1|root,COG3344@2|Bacteria,1MVI1@1224|Proteobacteria,42RS8@68525|delta/epsilon subdivisions,2WND0@28221|Deltaproteobacteria,43UCV@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	PFAM RNA-directed DNA polymerase (Reverse transcriptase)	-	-	2.7.7.49	ko:K00986	-	-	-	-	ko00000,ko01000	-	-	-	Cas_Cas1,GIIM,RVT_1
k59_29842_1	1121439.dsat_1103	6.42e-31	112.0	COG1366@1|root,COG1366@2|Bacteria,1N7D9@1224|Proteobacteria,42V1I@68525|delta/epsilon subdivisions,2WRH0@28221|Deltaproteobacteria,2MD3V@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	transporter antisigma-factor antagonist STAS	-	-	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS
k59_174294_1	177437.HRM2_00870	6.71e-23	97.8	COG3303@1|root,COG3303@2|Bacteria,1P8CP@1224|Proteobacteria,42MXS@68525|delta/epsilon subdivisions,2WKEK@28221|Deltaproteobacteria,2MI5R@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Seven times multi-haem cytochrome CxxCH	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554,Multi-haem_cyto
k59_174294_2	485915.Dret_2384	4.95e-90	269.0	COG3005@1|root,COG3005@2|Bacteria,1RIC0@1224|Proteobacteria,42NW0@68525|delta/epsilon subdivisions,2WK0R@28221|Deltaproteobacteria,2MB00@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	Cytochrome c-type protein	-	-	-	ko:K02569,ko:K03532	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	5.A.3.4	-	-	Cytochrom_NNT
k59_242190_1	177437.HRM2_41800	1.17e-73	236.0	2DBU2@1|root,2ZB3S@2|Bacteria,1N1MT@1224|Proteobacteria,42VJX@68525|delta/epsilon subdivisions,2WSPP@28221|Deltaproteobacteria,2MNKM@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_4
k59_98464_1	1049564.TevJSym_ac01220	5.71e-39	143.0	COG1420@1|root,COG1420@2|Bacteria,1MVX4@1224|Proteobacteria,1RR2F@1236|Gammaproteobacteria,1J95I@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	K	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons	hrcA	-	-	ko:K03705	-	-	-	-	ko00000,ko03000	-	-	-	HrcA,HrcA_DNA-bdg
k59_22330_1	1121405.dsmv_2732	2.37e-93	298.0	COG0532@1|root,COG0532@2|Bacteria,1MV26@1224|Proteobacteria,42M5Q@68525|delta/epsilon subdivisions,2WIIX@28221|Deltaproteobacteria,2MIGT@213118|Desulfobacterales	28221|Deltaproteobacteria	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,IF-2,IF2_N
k59_98467_1	926550.CLDAP_08070	1.87e-35	135.0	COG1714@1|root,COG1714@2|Bacteria,2G7CB@200795|Chloroflexi	200795|Chloroflexi	S	PFAM RDD domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	RDD
k59_166248_1	391612.CY0110_02722	3.64e-78	244.0	COG1404@1|root,COG1404@2|Bacteria,1G04W@1117|Cyanobacteria	1117|Cyanobacteria	O	PFAM Proprotein convertase P-domain	prcA	-	-	-	-	-	-	-	-	-	-	-	P_proprotein,Peptidase_S8
k59_67798_1	269799.Gmet_0852	3.11e-151	436.0	COG0343@1|root,COG0343@2|Bacteria,1MUCA@1224|Proteobacteria,42M5Y@68525|delta/epsilon subdivisions,2WIMT@28221|Deltaproteobacteria,43TNC@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	tgt	-	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
k59_67798_2	645512.GCWU000246_01871	0.000798	43.5	COG1862@1|root,COG1862@2|Bacteria,3TBBD@508458|Synergistetes	508458|Synergistetes	U	TIGRFAM preprotein translocase, YajC subunit	yajC	-	-	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	YajC
k59_29855_1	368408.Tpen_0588	5.61e-79	258.0	COG0574@1|root,arCOG01111@2157|Archaea,2XPWQ@28889|Crenarchaeota	28889|Crenarchaeota	G	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate	ppsA	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
k59_166249_1	338963.Pcar_0451	3.92e-33	125.0	COG2854@1|root,COG2854@2|Bacteria,1NKFA@1224|Proteobacteria,42U8G@68525|delta/epsilon subdivisions,2WQPS@28221|Deltaproteobacteria,43UX2@69541|Desulfuromonadales	28221|Deltaproteobacteria	Q	MlaC protein	-	-	-	ko:K07323	ko02010,map02010	M00210	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27.3	-	-	MlaC
k59_196518_1	1121468.AUBR01000036_gene1308	2.95e-66	227.0	COG2203@1|root,COG3437@1|root,COG3605@1|root,COG4936@1|root,COG2203@2|Bacteria,COG3437@2|Bacteria,COG3605@2|Bacteria,COG4936@2|Bacteria,1V7YT@1239|Firmicutes,25ET2@186801|Clostridia,42JGC@68295|Thermoanaerobacterales	186801|Clostridia	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HD,PocR,SBP_bac_3
k59_98490_1	1121405.dsmv_0324	3.76e-138	411.0	COG0480@1|root,COG0480@2|Bacteria,1MUCV@1224|Proteobacteria,42M4T@68525|delta/epsilon subdivisions,2WIM7@28221|Deltaproteobacteria,2MIK2@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA-2	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
k59_98490_2	933262.AXAM01000038_gene910	3.18e-23	94.4	COG5401@1|root,COG5401@2|Bacteria,1NA0G@1224|Proteobacteria,42V1V@68525|delta/epsilon subdivisions,2WRCV@28221|Deltaproteobacteria,2MKUK@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Sporulation and spore germination	-	-	-	-	-	-	-	-	-	-	-	-	Germane
k59_181427_1	742821.HMPREF9464_00954	8.04e-05	48.5	COG0262@1|root,COG0262@2|Bacteria,1RH0P@1224|Proteobacteria,2VSH8@28216|Betaproteobacteria,4PR6G@995019|Sutterellaceae	28216|Betaproteobacteria	H	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis	folA	-	1.5.1.3	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	M00126,M00840	R00936,R00937,R00939,R00940,R02235,R02236,R11765	RC00109,RC00110,RC00158	ko00000,ko00001,ko00002,ko01000	-	-	-	DHFR_1
k59_22363_1	90813.JQMT01000001_gene1057	5.29e-55	184.0	COG2826@1|root,COG2826@2|Bacteria,1MWI0@1224|Proteobacteria,1RRSE@1236|Gammaproteobacteria,461TE@72273|Thiotrichales	72273|Thiotrichales	L	Homeodomain-like domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_38,rve
k59_98496_1	366602.Caul_4644	4.82e-15	85.1	COG2982@1|root,COG2982@2|Bacteria,1MUAN@1224|Proteobacteria,2U26R@28211|Alphaproteobacteria,2KEYV@204458|Caulobacterales	204458|Caulobacterales	M	AsmA family	-	-	-	ko:K07290	-	-	-	-	ko00000	9.B.121	-	-	AsmA
k59_166274_1	880073.Calab_1611	2.18e-47	171.0	COG0642@1|root,COG4191@1|root,COG2205@2|Bacteria,COG4191@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
k59_151156_1	1121396.KB893066_gene1581	8.1e-47	171.0	COG0834@1|root,COG4191@1|root,COG0834@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MC4@68525|delta/epsilon subdivisions,2WIZU@28221|Deltaproteobacteria,2MJ29@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg,SBP_bac_3,dCache_3
k59_98501_1	1265505.ATUG01000002_gene1713	3.61e-87	283.0	COG0404@1|root,COG0446@1|root,COG0404@2|Bacteria,COG0446@2|Bacteria,1MVEK@1224|Proteobacteria,42P3Z@68525|delta/epsilon subdivisions,2WKRN@28221|Deltaproteobacteria,2MJ14@213118|Desulfobacterales	28221|Deltaproteobacteria	C	2Fe-2S iron-sulfur cluster binding domain	-	-	1.5.3.1	ko:K00302	ko00260,ko01100,map00260,map01100	-	R00610	RC00060,RC00557	ko00000,ko00001,ko01000	-	-	-	Fer2_4,Fer2_BFD,GCV_T,GCV_T_C,Pyr_redox_2
k59_114123_1	391625.PPSIR1_41444	8.01e-73	236.0	COG1680@1|root,COG1680@2|Bacteria,1MY4Y@1224|Proteobacteria,42ZU5@68525|delta/epsilon subdivisions,2WV5X@28221|Deltaproteobacteria,2YUT0@29|Myxococcales	28221|Deltaproteobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
k59_8079_1	297246.lpp2499	1.8e-41	148.0	COG1409@1|root,COG1409@2|Bacteria,1N2UT@1224|Proteobacteria	1224|Proteobacteria	E	Calcineurin-like phosphoesterase	phoA	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,Metallophos,Metallophos_C
k59_227834_1	335543.Sfum_3047	7.94e-66	212.0	COG0313@1|root,COG0313@2|Bacteria,1MU0E@1224|Proteobacteria,42P3I@68525|delta/epsilon subdivisions,2WM37@28221|Deltaproteobacteria,2MQHP@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA	rsmI	-	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
k59_235509_1	555779.Dthio_PD0479	7.29e-16	72.0	COG3093@1|root,COG3093@2|Bacteria,1N76J@1224|Proteobacteria,42VQB@68525|delta/epsilon subdivisions,2WRF4@28221|Deltaproteobacteria,2MD69@213115|Desulfovibrionales	28221|Deltaproteobacteria	K	TIGRFAM Addiction module antidote protein, HigA	-	-	-	ko:K21498	-	-	-	-	ko00000,ko02048	-	-	-	HTH_3
k59_235509_2	1205680.CAKO01000017_gene28	8.52e-33	116.0	COG3549@1|root,COG3549@2|Bacteria,1PU0P@1224|Proteobacteria,2VCRI@28211|Alphaproteobacteria,2JTZ6@204441|Rhodospirillales	204441|Rhodospirillales	S	RelE-like toxin of type II toxin-antitoxin system HigB	-	-	-	ko:K07334	-	-	-	-	ko00000,ko02048	-	-	-	HigB-like_toxin
k59_114124_1	1121405.dsmv_1661	1.24e-101	307.0	COG3278@1|root,COG3278@2|Bacteria,1MU18@1224|Proteobacteria,42M5M@68525|delta/epsilon subdivisions,2WM27@28221|Deltaproteobacteria,2MJRK@213118|Desulfobacterales	28221|Deltaproteobacteria	C	cytochrome c oxidase	ccoN	-	1.9.3.1	ko:K00404	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	COX1
k59_91393_2	1279009.ADICEAN_00363	1.29e-64	208.0	COG0111@1|root,COG0111@2|Bacteria,4NE9J@976|Bacteroidetes,47JBD@768503|Cytophagia	976|Bacteroidetes	EH	D-isomer specific 2-hydroxyacid dehydrogenase	ghrA	-	1.1.1.79,1.1.1.81	ko:K12972	ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00260,map00620,map00630,map01100,map01110,map01120	-	R00465,R01388,R01392,R02527	RC00031,RC00042,RC00670	ko00000,ko00001,ko01000	-	-	-	2-Hacid_dh_C
k59_61245_1	1169143.KB911035_gene2095	1.61e-34	129.0	COG5361@1|root,COG5361@2|Bacteria,1PB8E@1224|Proteobacteria,2VZ7I@28216|Betaproteobacteria,1K60R@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF1214)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1214,DUF1254
k59_235513_1	765912.Thimo_0884	1.02e-95	293.0	COG1850@1|root,COG1850@2|Bacteria,1MWEB@1224|Proteobacteria,1RZ4S@1236|Gammaproteobacteria,1WX7Q@135613|Chromatiales	135613|Chromatiales	G	PFAM Ribulose bisphosphate carboxylase large	-	-	4.1.1.39	ko:K01601	ko00630,ko00710,ko01100,ko01120,ko01200,map00630,map00710,map01100,map01120,map01200	M00165,M00166,M00532	R00024,R03140	RC00172,RC00859	ko00000,ko00001,ko00002,ko01000	-	-	-	RuBisCO_large,RuBisCO_large_N
k59_136955_1	247490.KSU1_D0223	1.06e-62	213.0	COG0633@1|root,COG3894@1|root,COG0633@2|Bacteria,COG3894@2|Bacteria,2J2QB@203682|Planctomycetes	203682|Planctomycetes	C	Domain of unknown function (DUF4445)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4445,Fer2
k59_235514_1	933262.AXAM01000016_gene161	4.3e-38	129.0	COG0228@1|root,COG0228@2|Bacteria,1MZCT@1224|Proteobacteria,42V30@68525|delta/epsilon subdivisions,2WRH7@28221|Deltaproteobacteria,2MKIH@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Belongs to the bacterial ribosomal protein bS16 family	rpsP	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02959	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S16
k59_129362_1	1304888.ATWF01000001_gene2451	2.93e-71	222.0	COG0463@1|root,COG0463@2|Bacteria,2GGMK@200930|Deferribacteres	200930|Deferribacteres	M	Glycosyl transferase family 2	-	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
k59_38414_1	1250232.JQNJ01000001_gene2906	5.33e-19	91.3	COG5283@1|root,COG5283@2|Bacteria,4NIZH@976|Bacteroidetes	976|Bacteroidetes	D	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PhageMin_Tail
k59_152069_1	1195236.CTER_4832	5.25e-48	164.0	COG1811@1|root,COG1811@2|Bacteria,1UH19@1239|Firmicutes,24AZ3@186801|Clostridia,3WINZ@541000|Ruminococcaceae	186801|Clostridia	S	Na channel or pump	-	-	-	ko:K07150	-	-	-	-	ko00000	-	-	-	DUF554
k59_45931_2	880072.Desac_2716	1.34e-55	178.0	COG0764@1|root,COG0764@2|Bacteria,1RH2T@1224|Proteobacteria,42SCN@68525|delta/epsilon subdivisions,2WP3E@28221|Deltaproteobacteria,2MQIG@213462|Syntrophobacterales	28221|Deltaproteobacteria	I	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs	fabZ	-	4.2.1.59	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121	RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FabA
k59_45931_3	443144.GM21_3419	6.52e-22	95.9	COG1044@1|root,COG1044@2|Bacteria,1MUX6@1224|Proteobacteria,42M4X@68525|delta/epsilon subdivisions,2WJJY@28221|Deltaproteobacteria,43TUE@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxD	GO:0003674,GO:0003824,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	2.3.1.191	ko:K02536	ko00540,ko01100,map00540,map01100	M00060	R04550	RC00039,RC00166	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hexapep,Hexapep_2,LpxD
k59_144486_1	338963.Pcar_3121	1.31e-52	184.0	2E2HF@1|root,32XMD@2|Bacteria,1N5B9@1224|Proteobacteria,42WRZ@68525|delta/epsilon subdivisions,2WRVW@28221|Deltaproteobacteria,43VYK@69541|Desulfuromonadales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_23217_1	1121396.KB893101_gene476	4.63e-89	272.0	COG2025@1|root,COG2025@2|Bacteria,1MUFI@1224|Proteobacteria,42MH7@68525|delta/epsilon subdivisions,2WK12@28221|Deltaproteobacteria,2MIA2@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM Electron transfer flavoprotein alpha	-	-	-	ko:K03522	-	-	-	-	ko00000,ko04147	-	-	-	ETF,ETF_alpha
k59_23217_2	879212.DespoDRAFT_02543	3.43e-36	129.0	COG2086@1|root,COG2086@2|Bacteria,1MVH6@1224|Proteobacteria,42PYM@68525|delta/epsilon subdivisions,2WJ37@28221|Deltaproteobacteria,2MIP8@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Electron transfer flavoprotein	-	-	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
k59_68758_1	880072.Desac_1620	1.55e-125	374.0	COG1797@1|root,COG1797@2|Bacteria,1MV7Z@1224|Proteobacteria,42M8T@68525|delta/epsilon subdivisions,2WIXE@28221|Deltaproteobacteria,2MQYU@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source	cbiA	-	6.3.5.11,6.3.5.9	ko:K02224	ko00860,ko01100,ko01120,map00860,map01100,map01120	-	R05224,R05815	RC00010,RC01301	ko00000,ko00001,ko01000	-	-	-	AAA_26,CbiA,GATase_3
k59_205263_2	1248232.BANQ01000020_gene144	2.46e-05	48.5	COG0838@1|root,COG0838@2|Bacteria,1RGUT@1224|Proteobacteria,1S644@1236|Gammaproteobacteria,1Y0TC@135623|Vibrionales	135623|Vibrionales	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_q4
k59_144488_1	1304885.AUEY01000028_gene2790	2.08e-92	280.0	COG0150@1|root,COG0150@2|Bacteria,1MURG@1224|Proteobacteria,42KZT@68525|delta/epsilon subdivisions,2WIXY@28221|Deltaproteobacteria,2MHNK@213118|Desulfobacterales	28221|Deltaproteobacteria	F	PFAM AIR synthase related protein	purM	-	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1844	AIRS,AIRS_C
k59_220445_1	439235.Dalk_0551	6.78e-46	161.0	COG0392@1|root,COG0392@2|Bacteria,1R98C@1224|Proteobacteria,42U6V@68525|delta/epsilon subdivisions,2WKTZ@28221|Deltaproteobacteria,2MJCJ@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
k59_167195_1	388467.A19Y_4547	1.1e-55	192.0	COG0280@1|root,COG0857@1|root,COG0280@2|Bacteria,COG0857@2|Bacteria,1G16R@1117|Cyanobacteria,1H85V@1150|Oscillatoriales	1117|Cyanobacteria	C	belongs to the CobB CobQ family	pta	-	2.3.1.8	ko:K13788	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00230,R00921	RC00004,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_26,DRTGG,PTA_PTB
k59_98998_1	1121396.KB893077_gene745	3.25e-35	136.0	COG1075@1|root,COG1075@2|Bacteria,1R5PF@1224|Proteobacteria,43BHB@68525|delta/epsilon subdivisions,2X6VQ@28221|Deltaproteobacteria,2MMMX@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Alpha/beta hydrolase of unknown function (DUF915)	-	-	-	-	-	-	-	-	-	-	-	-	DUF915
k59_53549_1	335543.Sfum_3112	1.09e-56	196.0	COG0784@1|root,COG4191@1|root,COG0784@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42M1R@68525|delta/epsilon subdivisions,2WK3J@28221|Deltaproteobacteria,2MSIC@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
k59_76273_1	96561.Dole_0326	2.04e-15	75.9	COG2329@1|root,COG2329@2|Bacteria,1NBCH@1224|Proteobacteria,42VX2@68525|delta/epsilon subdivisions,2WRPB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_136967_1	880072.Desac_1312	2.34e-120	373.0	COG0046@1|root,COG1828@1|root,COG0046@2|Bacteria,COG1828@2|Bacteria,1MYN4@1224|Proteobacteria,42M08@68525|delta/epsilon subdivisions,2WITS@28221|Deltaproteobacteria,2MR4G@213462|Syntrophobacterales	28221|Deltaproteobacteria	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C,PurS
k59_83827_1	1005048.CFU_2263	4.46e-44	161.0	COG1463@1|root,COG3008@1|root,COG1463@2|Bacteria,COG3008@2|Bacteria,1MU1T@1224|Proteobacteria,2VJ44@28216|Betaproteobacteria,4725P@75682|Oxalobacteraceae	28216|Betaproteobacteria	Q	MlaD protein	pqiB	-	-	ko:K06192	-	-	-	-	ko00000	-	-	-	MlaD
k59_76301_1	1301098.PKB_1993	1.23e-84	268.0	COG1123@1|root,COG4172@2|Bacteria,1MU09@1224|Proteobacteria,1RMEI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	Belongs to the ABC transporter superfamily	yejF	GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006857,GO:0008144,GO:0008150,GO:0015399,GO:0015405,GO:0015833,GO:0015893,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0035672,GO:0036094,GO:0042221,GO:0042493,GO:0042623,GO:0042626,GO:0042884,GO:0042886,GO:0042891,GO:0043167,GO:0043168,GO:0043492,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	ko:K13896	ko02010,map02010	M00349	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.21,3.A.1.5.24	-	-	ABC_tran,oligo_HPY
k59_45955_1	1121403.AUCV01000056_gene3012	3.89e-59	200.0	COG0661@1|root,COG0661@2|Bacteria,1MU1Z@1224|Proteobacteria,42N87@68525|delta/epsilon subdivisions,2WK1B@28221|Deltaproteobacteria,2MHU5@213118|Desulfobacterales	28221|Deltaproteobacteria	S	pfam abc-1	-	-	-	ko:K03688	-	-	-	-	ko00000	-	-	-	ABC1,APH
k59_38432_1	247490.KSU1_C0986	2.58e-39	147.0	COG0617@1|root,COG0617@2|Bacteria,2IXYM@203682|Planctomycetes	203682|Planctomycetes	H	tRNA nucleotidyltransferase poly(A) polymerase	papS	-	2.7.7.19,2.7.7.72	ko:K00970,ko:K00974	ko03013,ko03018,map03013,map03018	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	HD,PolyA_pol,PolyA_pol_RNAbd,tRNA_NucTran2_2
k59_152096_3	351627.Csac_1681	2.53e-05	48.5	COG0457@1|root,COG0463@1|root,COG0457@2|Bacteria,COG0463@2|Bacteria,1TRCN@1239|Firmicutes,25E6P@186801|Clostridia,42J3X@68295|Thermoanaerobacterales	186801|Clostridia	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
k59_23231_1	240016.ABIZ01000001_gene5928	2.38e-65	226.0	COG0178@1|root,COG0178@2|Bacteria,46SAF@74201|Verrucomicrobia,2ITHY@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
k59_91409_1	411902.CLOBOL_06507	2.88e-28	114.0	COG0653@1|root,COG0653@2|Bacteria,1TPEY@1239|Firmicutes,247N2@186801|Clostridia,21YP5@1506553|Lachnoclostridium	186801|Clostridia	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	-	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	Helicase_C,SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
k59_91409_2	1322246.BN4_10186	2.74e-13	68.2	COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,42P5W@68525|delta/epsilon subdivisions,2WMA6@28221|Deltaproteobacteria,2M8GP@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	PFAM Peptidase M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
k59_205285_2	745411.B3C1_14218	8.27e-30	120.0	COG0188@1|root,COG0188@2|Bacteria,1MURI@1224|Proteobacteria,1RMTC@1236|Gammaproteobacteria,1J4FT@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	L	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule	parC	GO:0000819,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006265,GO:0006276,GO:0006725,GO:0006807,GO:0006996,GO:0007049,GO:0007059,GO:0007062,GO:0008150,GO:0008152,GO:0009330,GO:0009987,GO:0016020,GO:0016043,GO:0019897,GO:0019898,GO:0022402,GO:0030541,GO:0032991,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0098813,GO:1901360,GO:1901363	-	ko:K02621	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
k59_152102_2	1254432.SCE1572_23510	4.45e-10	60.5	COG2919@1|root,COG2919@2|Bacteria,1NM5U@1224|Proteobacteria,42X2K@68525|delta/epsilon subdivisions,2WSPM@28221|Deltaproteobacteria,2YW2R@29|Myxococcales	28221|Deltaproteobacteria	D	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic	divIC	-	-	ko:K05589,ko:K13052	-	-	-	-	ko00000,ko03036	-	-	-	DivIC
k59_15630_1	1120983.KB894574_gene1005	3.35e-15	78.2	COG3677@1|root,COG3677@2|Bacteria,1MXYX@1224|Proteobacteria,2TQR3@28211|Alphaproteobacteria,1JPHB@119043|Rhodobiaceae	28211|Alphaproteobacteria	L	Transposase zinc-ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS1595,Zn_Tnp_IS1595
k59_15630_2	246200.SPO0479	4.38e-53	179.0	COG3676@1|root,COG3677@1|root,COG3676@2|Bacteria,COG3677@2|Bacteria,1MXYX@1224|Proteobacteria,2TQR3@28211|Alphaproteobacteria,4NDP6@97050|Ruegeria	28211|Alphaproteobacteria	L	ISXO2-like transposase domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS1595,Zn_Tnp_IS1595
k59_68787_1	768706.Desor_3625	2.29e-31	127.0	COG0587@1|root,COG0587@2|Bacteria,1TPYG@1239|Firmicutes,247U0@186801|Clostridia,2605R@186807|Peptococcaceae	186801|Clostridia	L	DNA polymerase III alpha subunit	dnaE	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
k59_182387_1	706587.Desti_1281	9.97e-44	152.0	COG1180@1|root,COG1180@2|Bacteria,1NQC1@1224|Proteobacteria,42QX3@68525|delta/epsilon subdivisions,2WPC7@28221|Deltaproteobacteria,2MRS6@213462|Syntrophobacterales	28221|Deltaproteobacteria	O	4Fe-4S single cluster domain	pflA	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
k59_83842_1	933262.AXAM01000014_gene275	1.01e-151	440.0	COG0519@1|root,COG0519@2|Bacteria,1MU2A@1224|Proteobacteria,42M0I@68525|delta/epsilon subdivisions,2WJ6D@28221|Deltaproteobacteria,2MJ7G@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Catalyzes the synthesis of GMP from XMP	guaA	GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase,tRNA_Me_trans
k59_3298_1	1449126.JQKL01000043_gene1900	0.000595	42.4	COG0247@1|root,COG0247@2|Bacteria,1TPG1@1239|Firmicutes,24BBE@186801|Clostridia	186801|Clostridia	C	Fe-S oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_8,Nitrate_red_gam
k59_3298_2	335543.Sfum_0108	3.04e-38	142.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,42M5F@68525|delta/epsilon subdivisions,2WISF@28221|Deltaproteobacteria,2MSIT@213462|Syntrophobacterales	28221|Deltaproteobacteria	IQ	AMP-dependent synthetase and ligase	fadD	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
k59_132955_1	880072.Desac_1008	1.87e-58	186.0	COG4871@1|root,COG4871@2|Bacteria	880072.Desac_1008|-	C	Putative Fe-S cluster	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_110506_1	443143.GM18_3205	2.83e-39	144.0	COG1243@1|root,COG1243@2|Bacteria,1MUYS@1224|Proteobacteria,42N2I@68525|delta/epsilon subdivisions,2WKZX@28221|Deltaproteobacteria,43TDM@69541|Desulfuromonadales	28221|Deltaproteobacteria	BK	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM,Radical_SAM_C
k59_201447_1	861208.AGROH133_15140	1.02e-64	206.0	COG1280@1|root,COG1280@2|Bacteria,1MWA1@1224|Proteobacteria,2V825@28211|Alphaproteobacteria,4BG91@82115|Rhizobiaceae	28211|Alphaproteobacteria	E	LysE type translocator	-	-	-	-	-	-	-	-	-	-	-	-	LysE
k59_72620_1	96561.Dole_2249	1.87e-16	80.5	2E0M7@1|root,32W6F@2|Bacteria,1NB9Z@1224|Proteobacteria,42W6T@68525|delta/epsilon subdivisions,2WSFF@28221|Deltaproteobacteria,2MNT8@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_216306_1	335543.Sfum_1999	6.78e-73	238.0	COG1053@1|root,COG1053@2|Bacteria,1MU5M@1224|Proteobacteria,42M81@68525|delta/epsilon subdivisions,2WJXY@28221|Deltaproteobacteria,2MQTE@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	TIGRFAM succinate dehydrogenase or fumarate reductase, flavoprotein	sdhA	-	1.3.5.1,1.3.5.4	ko:K00239,ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,ko05134,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020,map05134	M00009,M00011,M00149,M00150,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
k59_147707_1	107636.JQNK01000009_gene1523	2.76e-09	58.2	COG0626@1|root,COG0626@2|Bacteria,1MU57@1224|Proteobacteria,2TW14@28211|Alphaproteobacteria,36ZFE@31993|Methylocystaceae	28211|Alphaproteobacteria	E	Cys/Met metabolism PLP-dependent enzyme	mdeA	-	2.5.1.48,4.4.1.11	ko:K01739,ko:K01761	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017	R00654,R00999,R01288,R02508,R03217,R03260,R04770,R04944,R04945,R04946	RC00020,RC00056,RC00069,RC00196,RC00348,RC00420,RC01209,RC01210,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000	-	-	-	Cys_Met_Meta_PP
k59_238857_1	561229.Dd1591_2056	3.71e-28	120.0	COG0845@1|root,COG1994@1|root,COG0845@2|Bacteria,COG1994@2|Bacteria,1MW9I@1224|Proteobacteria,1RRTY@1236|Gammaproteobacteria,2JD1H@204037|Dickeya	1236|Gammaproteobacteria	M	Biotin-lipoyl like	-	-	-	ko:K16922	-	-	-	-	ko00000,ko01002	-	-	-	Biotin_lipoyl_2,HlyD_3
k59_110519_1	1123228.AUIH01000009_gene1940	6.98e-17	78.6	28I6Z@1|root,2Z89U@2|Bacteria,1R8YM@1224|Proteobacteria,1S0GG@1236|Gammaproteobacteria,1XNAN@135619|Oceanospirillales	135619|Oceanospirillales	S	von Willebrand factor (vWF) type A domain	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_110519_2	1121935.AQXX01000142_gene2326	1.89e-27	112.0	28HC9@1|root,2Z7P5@2|Bacteria,1R4BH@1224|Proteobacteria,1RSAN@1236|Gammaproteobacteria,1XNEQ@135619|Oceanospirillales	135619|Oceanospirillales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_223785_1	335543.Sfum_2379	1.32e-76	265.0	COG0784@1|root,COG2202@1|root,COG3829@1|root,COG4191@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG3829@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MC4@68525|delta/epsilon subdivisions,2WIZU@28221|Deltaproteobacteria,2MR92@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_8,PAS_9,PocR,Response_reg,dCache_1
k59_216319_1	880072.Desac_1264	5.51e-35	137.0	COG2199@1|root,COG2203@1|root,COG2203@2|Bacteria,COG3706@2|Bacteria,1NECV@1224|Proteobacteria,42PZK@68525|delta/epsilon subdivisions,2WMIG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GGDEF
k59_57577_1	756272.Plabr_0747	1.3e-20	91.7	COG1678@1|root,COG1678@2|Bacteria,2J0F0@203682|Planctomycetes	203682|Planctomycetes	K	Transcriptional regulator	-	-	-	ko:K07735	-	-	-	-	ko00000,ko03000	-	-	-	DUF179
k59_193318_2	717605.Theco_0890	6.92e-09	58.5	COG1484@1|root,COG1484@2|Bacteria,1TPPI@1239|Firmicutes,4HAKP@91061|Bacilli,275FX@186822|Paenibacillaceae	91061|Bacilli	L	Bacterial dnaA  protein	-	-	-	-	-	-	-	-	-	-	-	-	IstB_IS21
k59_171155_1	333138.LQ50_10445	3.73e-11	66.2	COG1638@1|root,COG1638@2|Bacteria,1UY2X@1239|Firmicutes,4HCVD@91061|Bacilli,1ZFCD@1386|Bacillus	91061|Bacilli	G	COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component	-	-	-	-	-	-	-	-	-	-	-	-	DctP
k59_49523_1	96561.Dole_3250	5e-75	239.0	COG3039@1|root,COG3039@2|Bacteria,1QQ9Q@1224|Proteobacteria,42S7X@68525|delta/epsilon subdivisions,2WNJ2@28221|Deltaproteobacteria,2MJG4@213118|Desulfobacterales	28221|Deltaproteobacteria	L	PFAM transposase IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DUF772
k59_147725_1	880074.BARVI_03915	7.33e-86	264.0	COG3328@1|root,COG3328@2|Bacteria,4NY5M@976|Bacteroidetes,2FTUC@200643|Bacteroidia	976|Bacteroidetes	L	Transposase, Mutator family	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_mut
k59_34769_1	370438.PTH_1766	1.1e-50	176.0	COG0644@1|root,COG0644@2|Bacteria,1TRRU@1239|Firmicutes,2481K@186801|Clostridia,2604Q@186807|Peptococcaceae	186801|Clostridia	C	Oxidoreductase	-	-	-	ko:K00313	-	-	-	-	ko00000,ko01000	-	-	-	DAO,FAD_oxidored
k59_201475_1	1460634.JCM19037_732	2.15e-40	147.0	COG0626@1|root,COG0626@2|Bacteria,1TPC7@1239|Firmicutes,4HBQK@91061|Bacilli	91061|Bacilli	E	Methionine gamma-lyase	-	-	2.5.1.48	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017	R00999,R01288,R02508,R03217,R03260,R04944,R04945,R04946	RC00020,RC00056,RC00069,RC00420,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000	-	-	-	Cys_Met_Meta_PP
k59_49527_1	335543.Sfum_2647	1.47e-33	124.0	COG0022@1|root,COG0022@2|Bacteria,1R8KB@1224|Proteobacteria,42N06@68525|delta/epsilon subdivisions,2WK5N@28221|Deltaproteobacteria,2MR64@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	Transketolase, pyrimidine binding domain	bkdB	-	1.2.4.1,1.2.4.4	ko:K00162,ko:K00167	ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00036,M00307	R00014,R00209,R01699,R03270,R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00004,RC00027,RC00627,RC02742,RC02743,RC02744,RC02882,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
k59_49527_2	223184.AS25_08850	1.23e-09	60.5	COG0508@1|root,COG0508@2|Bacteria,2GM0D@201174|Actinobacteria,1W7XA@1268|Micrococcaceae	201174|Actinobacteria	C	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex	-	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
k59_156096_1	926550.CLDAP_28990	4.07e-20	96.3	COG0464@1|root,COG0464@2|Bacteria,2G87K@200795|Chloroflexi	200795|Chloroflexi	O	ATPase family associated with various cellular activities (AAA)	-	-	-	-	-	-	-	-	-	-	-	-	AAA
k59_3508_1	56780.SYN_01263	1.38e-81	254.0	COG1127@1|root,COG2199@1|root,COG1127@2|Bacteria,COG2199@2|Bacteria,1MUSD@1224|Proteobacteria,42NI4@68525|delta/epsilon subdivisions,2WKRT@28221|Deltaproteobacteria,2MQX9@213462|Syntrophobacterales	28221|Deltaproteobacteria	Q	ABC transporter	-	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran,GGDEF
k59_72650_1	502025.Hoch_1127	2.03e-12	67.4	COG3344@1|root,COG3344@2|Bacteria,1MVI1@1224|Proteobacteria,42Y93@68525|delta/epsilon subdivisions,2WU1Y@28221|Deltaproteobacteria,2YTTS@29|Myxococcales	28221|Deltaproteobacteria	H	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	GIIM,RVT_1
k59_34786_1	555779.Dthio_PD2541	6.53e-11	63.2	COG1270@1|root,COG1270@2|Bacteria,1MURM@1224|Proteobacteria,42PDX@68525|delta/epsilon subdivisions,2WKH4@28221|Deltaproteobacteria,2M8AJ@213115|Desulfovibrionales	28221|Deltaproteobacteria	H	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group	cobD	-	6.3.1.10	ko:K02227	ko00860,ko01100,map00860,map01100	M00122	R06529,R07302	RC00090,RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	CobD_Cbib
k59_34786_2	290318.Cvib_0815	1.54e-42	152.0	COG0079@1|root,COG0079@2|Bacteria,1FE4A@1090|Chlorobi	1090|Chlorobi	E	PFAM aminotransferase, class I and II	-	-	2.6.1.9,4.1.1.81	ko:K00817,ko:K04720	ko00340,ko00350,ko00360,ko00400,ko00401,ko00860,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00860,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243,R06530	RC00006,RC00517,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
k59_133411_1	933262.AXAM01000016_gene191	6.5e-46	154.0	COG0670@1|root,COG0670@2|Bacteria,1MU69@1224|Proteobacteria,42MWD@68525|delta/epsilon subdivisions,2WMG9@28221|Deltaproteobacteria,2MJCA@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Belongs to the BI1 family	ybhL	-	-	ko:K06890,ko:K19416	-	M00742	-	-	ko00000,ko00002,ko02000	1.A.14.2.1	-	-	Bax1-I
k59_133411_2	326442.PSHAa0163	5.68e-06	54.3	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria,2Q0N0@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	T	COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains	glnG	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K07712	ko02020,map02020	M00497	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
k59_141006_1	1532558.JL39_15220	0.000247	48.9	COG1638@1|root,COG1638@2|Bacteria,1MVYB@1224|Proteobacteria,2TT88@28211|Alphaproteobacteria,4BB09@82115|Rhizobiaceae	28211|Alphaproteobacteria	G	Bacterial extracellular solute-binding protein, family 7	-	-	-	-	-	-	-	-	-	-	-	-	DctP
k59_80259_1	1121405.dsmv_3773	1.44e-106	335.0	COG0567@1|root,COG0567@2|Bacteria,1MVBF@1224|Proteobacteria,42NY6@68525|delta/epsilon subdivisions,2WJSE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Dehydrogenase E1 component	sucA	-	1.2.4.2	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R00621,R01933,R01940,R03316,R08549	RC00004,RC00027,RC00627,RC02743,RC02833,RC02883	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr
k59_64627_1	290397.Adeh_3072	2.64e-16	87.0	2AIHE@1|root,318Z9@2|Bacteria,1NWQ1@1224|Proteobacteria,42ZTQ@68525|delta/epsilon subdivisions,2WV9Q@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_147755_1	412597.AEPN01000031_gene524	6.14e-27	108.0	COG2945@1|root,COG2945@2|Bacteria,1MUDY@1224|Proteobacteria,2TRMI@28211|Alphaproteobacteria,2PV3G@265|Paracoccus	28211|Alphaproteobacteria	S	X-Pro dipeptidyl-peptidase (S15 family)	QU41_16170	-	-	ko:K07018	-	-	-	-	ko00000	-	-	-	Hydrolase_4,Peptidase_S15
k59_133417_1	386415.NT01CX_0936	4.26e-34	133.0	COG1199@1|root,COG1199@2|Bacteria,1TPNB@1239|Firmicutes,248ZI@186801|Clostridia,36E0Y@31979|Clostridiaceae	186801|Clostridia	L	helicase	dinG	-	3.1.12.1,3.6.4.12	ko:K07464,ko:K10844	ko03022,ko03420,map03022,map03420	M00290	-	-	ko00000,ko00001,ko00002,ko01000,ko02048,ko03021,ko03400	-	-	-	DEAD,DEAD_2,HBB,Helicase_C_2,PDDEXK_1
k59_201480_1	335543.Sfum_2498	3.59e-67	218.0	COG4591@1|root,COG4591@2|Bacteria,1R4Q2@1224|Proteobacteria,42PIT@68525|delta/epsilon subdivisions,2WKT1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	COG4591 ABC-type transport system, involved in lipoprotein release, permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
k59_102916_1	344747.PM8797T_21943	1.44e-54	182.0	COG0451@1|root,COG0451@2|Bacteria,2IYGP@203682|Planctomycetes	203682|Planctomycetes	M	PFAM NAD dependent epimerase dehydratase family	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
k59_41752_1	1230460.C495_10784	2.09e-05	49.3	COG2047@1|root,arCOG00348@2157|Archaea,2XSX4@28890|Euryarchaeota,23SFH@183963|Halobacteria	183963|Halobacteria	S	protein (ATP-grasp superfamily)	-	-	-	ko:K07159	-	-	-	-	ko00000	-	-	-	PAC2
k59_12240_1	314345.SPV1_11601	0.000514	44.7	COG1333@1|root,COG1333@2|Bacteria,1N6XE@1224|Proteobacteria	1224|Proteobacteria	O	PFAM ResB family protein	resB	-	-	ko:K07399	-	-	-	-	ko00000	-	-	-	ResB
k59_186656_1	671143.DAMO_1757	5.29e-14	68.9	COG1677@1|root,COG1677@2|Bacteria,2NRRQ@2323|unclassified Bacteria	2|Bacteria	NU	Flagellar hook-basal body complex protein FliE	fliE	-	-	ko:K02408	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliE
k59_186656_2	933262.AXAM01000005_gene2525	2.83e-94	295.0	COG1766@1|root,COG1766@2|Bacteria,1MUQR@1224|Proteobacteria,42N04@68525|delta/epsilon subdivisions,2WJS0@28221|Deltaproteobacteria,2MHWU@213118|Desulfobacterales	28221|Deltaproteobacteria	N	The M ring may be actively involved in energy transduction	fliF	-	-	ko:K02409	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	YscJ_FliF,YscJ_FliF_C
k59_156108_1	1121405.dsmv_0136	1.56e-58	197.0	COG3850@1|root,COG4191@1|root,COG3850@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42NFY@68525|delta/epsilon subdivisions,2WJKV@28221|Deltaproteobacteria,2MIPK@213118|Desulfobacterales	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_9
k59_80261_1	1121405.dsmv_2622	5.62e-166	479.0	COG0527@1|root,COG0527@2|Bacteria,1MW3H@1224|Proteobacteria,42PZ6@68525|delta/epsilon subdivisions,2WKNQ@28221|Deltaproteobacteria,2MI1H@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Amino acid kinase family	-	-	1.1.1.3,2.7.2.4	ko:K00928,ko:K12524	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480,R01773,R01775	RC00002,RC00043,RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT,ACT_7,Homoserine_dh,NAD_binding_3
k59_201496_1	1150864.MILUP08_42570	2.67e-37	135.0	COG0078@1|root,COG0078@2|Bacteria,2GJ6H@201174|Actinobacteria,4DAH1@85008|Micromonosporales	201174|Actinobacteria	E	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline	argF	GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0040007,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.1.3.3	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844	R01398	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
k59_201496_2	563040.Saut_0878	4.16e-17	79.7	COG0137@1|root,COG0137@2|Bacteria,1MV0Y@1224|Proteobacteria,42N81@68525|delta/epsilon subdivisions,2YMAU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Belongs to the argininosuccinate synthase family. Type 1 subfamily	argG	-	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Arginosuc_synth
k59_102930_1	1056820.KB900681_gene2859	8.47e-124	363.0	COG3385@1|root,COG3385@2|Bacteria,1PMXF@1224|Proteobacteria,1RMHK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	COG3385 FOG Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DUF4372
k59_186662_1	488538.SAR116_0190	1.96e-29	116.0	COG0730@1|root,COG0730@2|Bacteria,1Q2Z1@1224|Proteobacteria,2UJBP@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Sulfite exporter TauE/SafE	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
k59_193350_1	933262.AXAM01000084_gene1044	5.98e-44	153.0	COG2896@1|root,COG2896@2|Bacteria,1MW3W@1224|Proteobacteria,42NBV@68525|delta/epsilon subdivisions,2WK0F@28221|Deltaproteobacteria,2MI38@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate	moaA	GO:0003674,GO:0003824,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0071704,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.99.22	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394	RC03420	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Fer4_14,Mob_synth_C,Radical_SAM
k59_163136_1	572547.Amico_0584	0.000162	49.3	COG0628@1|root,COG0628@2|Bacteria,3TA0S@508458|Synergistetes	508458|Synergistetes	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
k59_133438_1	96561.Dole_2381	4.08e-54	188.0	COG1283@1|root,COG1283@2|Bacteria,1MUDE@1224|Proteobacteria,42PW9@68525|delta/epsilon subdivisions,2WJTI@28221|Deltaproteobacteria,2MJ12@213118|Desulfobacterales	28221|Deltaproteobacteria	P	PFAM Na Pi-cotransporter	-	-	-	ko:K03324	-	-	-	-	ko00000,ko02000	2.A.58.2	-	-	Na_Pi_cotrans,PhoU
k59_156113_1	644282.Deba_0776	4.33e-175	521.0	COG1703@1|root,COG1884@1|root,COG2185@1|root,COG1703@2|Bacteria,COG1884@2|Bacteria,COG2185@2|Bacteria,1MUXX@1224|Proteobacteria,42MVK@68525|delta/epsilon subdivisions,2WKEN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	EI	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly	icmF	-	5.4.99.13	ko:K11942	-	-	-	-	ko00000,ko01000	-	-	-	ArgK,B12-binding,MM_CoA_mutase
k59_216343_1	596151.DesfrDRAFT_0508	3.42e-19	85.1	COG1225@1|root,COG1225@2|Bacteria,1N3ZR@1224|Proteobacteria,42TQK@68525|delta/epsilon subdivisions,2WQSX@28221|Deltaproteobacteria,2MB7S@213115|Desulfovibrionales	28221|Deltaproteobacteria	O	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
k59_19157_1	240292.Ava_0231	1.97e-71	224.0	COG3335@1|root,COG3415@1|root,COG3335@2|Bacteria,COG3415@2|Bacteria	2|Bacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,DDE_Tnp_ISAZ013,DUF3105,HTH_28,HTH_33
k59_26583_1	697281.Mahau_1193	2.01e-31	124.0	COG1609@1|root,COG1609@2|Bacteria,1TQ7K@1239|Firmicutes,247M2@186801|Clostridia,42FY5@68295|Thermoanaerobacterales	186801|Clostridia	K	Periplasmic binding protein LacI transcriptional regulator	-	-	5.1.1.1	ko:K01775,ko:K02529,ko:K05499	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011,ko03000	-	-	-	LacI,Peripla_BP_3
k59_216344_1	335543.Sfum_3074	1.78e-56	184.0	COG1763@1|root,COG1763@2|Bacteria,1RD3Q@1224|Proteobacteria,42RZK@68525|delta/epsilon subdivisions,2WQ3C@28221|Deltaproteobacteria,2MQKK@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	Molybdopterin guanine dinucleotide synthesis protein B	mobB	-	2.7.7.77	ko:K03753,ko:K13818	ko00790,ko01100,map00790,map01100	-	R11581	-	ko00000,ko00001,ko01000	-	-	-	MobB,NTP_transf_3
k59_80266_1	1121405.dsmv_2932	1.15e-35	131.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,42MK5@68525|delta/epsilon subdivisions,2WJ3Z@28221|Deltaproteobacteria,2MIA8@213118|Desulfobacterales	28221|Deltaproteobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
k59_80266_2	1232437.KL661988_gene288	4.28e-19	87.0	COG1813@1|root,COG1917@1|root,COG1813@2|Bacteria,COG1917@2|Bacteria,1R8QC@1224|Proteobacteria,42NJP@68525|delta/epsilon subdivisions,2WMAB@28221|Deltaproteobacteria,2MIRS@213118|Desulfobacterales	28221|Deltaproteobacteria	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,HTH_3,HTH_31
k59_57620_1	698757.Pogu_0361	6.24e-15	79.0	COG1258@1|root,arCOG01015@2157|Archaea,2XQ08@28889|Crenarchaeota	28889|Crenarchaeota	J	Responsible for synthesis of pseudouridine from uracil- 54 and uracil-55 in the psi GC loop of transfer RNAs	pus10	-	5.4.99.25	ko:K07583	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	THUMP
k59_201504_5	298654.FraEuI1c_7196	1.87e-15	81.3	COG0860@1|root,COG3409@1|root,COG0860@2|Bacteria,COG3409@2|Bacteria,2GPA9@201174|Actinobacteria,4ERBQ@85013|Frankiales	201174|Actinobacteria	M	Cell wall hydrolase autolysin	cwlM	GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3,PG_binding_1
k59_117979_1	706587.Desti_2137	8.33e-113	345.0	COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,42MQS@68525|delta/epsilon subdivisions,2WINP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	1.1.1.35,4.2.1.17,5.1.2.3	ko:K01782,ko:K07516	ko00071,ko00280,ko00281,ko00310,ko00362,ko00380,ko00410,ko00640,ko00650,ko00903,ko00930,ko01040,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00071,map00280,map00281,map00310,map00362,map00380,map00410,map00640,map00650,map00903,map00930,map01040,map01100,map01110,map01120,map01130,map01200,map01212	M00032,M00087	R01975,R03026,R03045,R03276,R04137,R04170,R04203,R04204,R04224,R04737,R04738,R04739,R04740,R04741,R04743,R04744,R04745,R04746,R04748,R04749,R05066,R05305,R06411,R06412,R06941,R06942,R07935,R07951,R08093,R08094	RC00029,RC00099,RC00117,RC00241,RC00525,RC00831,RC00834,RC00896,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	3HCDH,3HCDH_N,ECH_1
k59_224304_1	880070.Cycma_1141	1.53e-11	65.9	COG1664@1|root,COG1664@2|Bacteria,4NUZA@976|Bacteroidetes,47RT9@768503|Cytophagia	976|Bacteroidetes	M	Polymer-forming cytoskeletal	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
k59_217235_2	933262.AXAM01000101_gene2550	7.26e-19	87.8	COG0711@1|root,COG0711@2|Bacteria,1ND52@1224|Proteobacteria,42V20@68525|delta/epsilon subdivisions,2WRR4@28221|Deltaproteobacteria,2MKYZ@213118|Desulfobacterales	28221|Deltaproteobacteria	C	ATP synthase B/B' CF(0)	-	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
k59_4266_1	1163398.AJJP01000074_gene2523	4.45e-51	176.0	COG2230@1|root,COG2230@2|Bacteria,1MX3U@1224|Proteobacteria,1S1KY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	COG2230 Cyclopropane fatty acid synthase and related methyltransferases	cfa2	-	2.1.1.79	ko:K00574	-	-	-	-	ko00000,ko01000	-	-	-	CMAS
k59_118298_1	519989.ECTPHS_14156	2.03e-68	210.0	COG1943@1|root,COG1943@2|Bacteria,1MX19@1224|Proteobacteria,1RSJY@1236|Gammaproteobacteria,1WY4B@135613|Chromatiales	135613|Chromatiales	L	PFAM Transposase	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
k59_73485_1	1123371.ATXH01000018_gene1394	3.73e-57	194.0	COG0111@1|root,COG2150@1|root,COG0111@2|Bacteria,COG2150@2|Bacteria,2GH7H@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	E	D-isomer specific 2-hydroxyacid dehydrogenase	-	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C,ACT
k59_141819_1	1121403.AUCV01000005_gene358	4.19e-14	77.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,43BKN@68525|delta/epsilon subdivisions,2X6YR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF3365,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
k59_164028_1	555779.Dthio_PD3244	1.52e-50	167.0	COG0655@1|root,COG0655@2|Bacteria,1RAZP@1224|Proteobacteria,42QXN@68525|delta/epsilon subdivisions,2WMR3@28221|Deltaproteobacteria,2MCCB@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
k59_35696_1	1304885.AUEY01000052_gene1554	1.36e-58	206.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,42P9Y@68525|delta/epsilon subdivisions,2WM6A@28221|Deltaproteobacteria,2MJCC@213118|Desulfobacterales	28221|Deltaproteobacteria	NTU	General secretory system II protein E domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,T2SSE,T2SSE_N
k59_35698_1	1499967.BAYZ01000135_gene85	3.11e-32	121.0	COG1127@1|root,COG1127@2|Bacteria,2NP3U@2323|unclassified Bacteria	2|Bacteria	Q	ABC-type transport system involved in resistance to organic solvents, ATPase component	ttg2A	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
k59_35698_2	525897.Dbac_0468	6.74e-19	85.1	COG0767@1|root,COG1366@1|root,COG0767@2|Bacteria,COG1366@2|Bacteria,1MVPN@1224|Proteobacteria,42MG3@68525|delta/epsilon subdivisions,2WKC7@28221|Deltaproteobacteria,2M940@213115|Desulfovibrionales	28221|Deltaproteobacteria	Q	Permease MlaE	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE,STAS_2
k59_179038_1	596151.DesfrDRAFT_3553	2.06e-62	214.0	COG1450@1|root,COG1450@2|Bacteria,1MUUA@1224|Proteobacteria,42M9I@68525|delta/epsilon subdivisions,2WK1H@28221|Deltaproteobacteria,2M98X@213115|Desulfovibrionales	28221|Deltaproteobacteria	NU	PFAM type II and III secretion system protein	gspD	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	Secretin,Secretin_N
k59_103874_1	526222.Desal_0371	2.73e-61	208.0	COG0243@1|root,COG0243@2|Bacteria,1P01N@1224|Proteobacteria,42M9D@68525|delta/epsilon subdivisions,2WJ43@28221|Deltaproteobacteria,2M8UY@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	1.8.5.5	ko:K08352	ko00920,ko01120,map00920,map01120	-	R10149	RC02823	ko00000,ko00001,ko01000,ko02000	5.A.3.5	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
k59_217254_1	439235.Dalk_2926	3.26e-65	205.0	COG1102@1|root,COG1102@2|Bacteria,1RCTZ@1224|Proteobacteria,42R0B@68525|delta/epsilon subdivisions,2WMVD@28221|Deltaproteobacteria,2MJH5@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Cytidylate kinase-like family	-	-	-	-	-	-	-	-	-	-	-	-	Cytidylate_kin2
k59_27291_1	28042.GU90_08250	1.14e-20	89.0	COG0491@1|root,COG0491@2|Bacteria,2GJU0@201174|Actinobacteria,4E019@85010|Pseudonocardiales	201174|Actinobacteria	S	Metallo-beta-lactamase superfamily	-	-	3.1.2.6	ko:K01069	ko00620,map00620	-	R01736	RC00004,RC00137	ko00000,ko00001,ko01000	-	-	-	Lactamase_B
k59_239740_1	1267533.KB906735_gene4730	1.34e-11	65.1	COG1506@1|root,COG1506@2|Bacteria,3Y357@57723|Acidobacteria,2JIKY@204432|Acidobacteriia	204432|Acidobacteriia	E	Tannase and feruloyl esterase	-	-	-	-	-	-	-	-	-	-	-	-	Tannase
k59_179047_1	247634.GPB2148_990	5.78e-92	288.0	28HMZ@1|root,2Z7WD@2|Bacteria,1MU3Q@1224|Proteobacteria,1RRUM@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF3604)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3604
k59_58577_1	1125863.JAFN01000001_gene1160	8.4e-69	221.0	COG0683@1|root,COG0683@2|Bacteria,1MWQB@1224|Proteobacteria,42PN2@68525|delta/epsilon subdivisions,2WM53@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	PFAM Extracellular ligand-binding receptor	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
k59_134287_1	228410.NE1093	1.36e-30	121.0	COG3666@1|root,COG3666@2|Bacteria,1N3QR@1224|Proteobacteria,2WADG@28216|Betaproteobacteria,374FC@32003|Nitrosomonadales	28216|Betaproteobacteria	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF772
k59_224687_1	565045.NOR51B_1051	1.23e-28	117.0	COG2079@1|root,COG2079@2|Bacteria,1R5UM@1224|Proteobacteria,1RSKM@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	MmgE/PrpD family	-	-	-	-	-	-	-	-	-	-	-	-	MmgE_PrpD
k59_13102_1	439235.Dalk_1966	5.07e-85	266.0	COG3604@1|root,COG3604@2|Bacteria,1QTT3@1224|Proteobacteria,42Y69@68525|delta/epsilon subdivisions,2WJ5F@28221|Deltaproteobacteria,2MI66@213118|Desulfobacterales	28221|Deltaproteobacteria	KT	PFAM sigma-54 factor interaction domain-containing protein	-	-	-	ko:K02584	ko02020,map02020	-	-	-	ko00000,ko00001,ko03000	-	-	-	GAF,GAF_2,HTH_8,Sigma54_activat
k59_111845_1	1121403.AUCV01000005_gene206	3.59e-80	238.0	COG1917@1|root,COG1917@2|Bacteria,1RH1V@1224|Proteobacteria,42U9N@68525|delta/epsilon subdivisions,2WUT7@28221|Deltaproteobacteria,2MNKF@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Cupin	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
k59_157377_1	596152.DesU5LDRAFT_2887	0.000306	47.8	COG0457@1|root,COG0457@2|Bacteria,1R438@1224|Proteobacteria,42PQ9@68525|delta/epsilon subdivisions,2WJ0C@28221|Deltaproteobacteria,2M83F@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	SMART Tetratricopeptide	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_10,TPR_11,TPR_16,TPR_19,TPR_2,TPR_8
k59_217801_1	420662.Mpe_A0326	4.9e-40	152.0	COG1080@1|root,COG1080@2|Bacteria,1MUT8@1224|Proteobacteria,2VH9N@28216|Betaproteobacteria,1KJSR@119065|unclassified Burkholderiales	28216|Betaproteobacteria	G	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)	ptsI	-	2.7.3.9	ko:K08483	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	8.A.7	-	-	PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C
k59_240274_1	315730.BcerKBAB4_3073	6e-12	68.2	COG2365@1|root,COG2365@2|Bacteria,1V851@1239|Firmicutes,4HJB2@91061|Bacilli,1ZHEI@1386|Bacillus	91061|Bacilli	T	Tyrosine phosphatase family	-	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	Y_phosphatase3
k59_118893_1	909663.KI867150_gene1321	2.63e-108	323.0	COG0500@1|root,COG1846@1|root,COG1846@2|Bacteria,COG2226@2|Bacteria,1MW7J@1224|Proteobacteria,43BRY@68525|delta/epsilon subdivisions,2X72R@28221|Deltaproteobacteria,2MQCD@213462|Syntrophobacterales	28221|Deltaproteobacteria	KQ	Dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	Dimerisation2,Methyltransf_2
k59_127167_4	556268.OFAG_00321	3.89e-46	162.0	COG1783@1|root,COG1783@2|Bacteria,1R66A@1224|Proteobacteria,2W8DW@28216|Betaproteobacteria,477HA@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Terminase RNAseH like domain	-	-	-	-	-	-	-	-	-	-	-	-	Terminase_3,Terminase_3C
k59_194636_1	1121405.dsmv_3587	1.09e-35	123.0	COG0089@1|root,COG0089@2|Bacteria,1MZXX@1224|Proteobacteria,42V3Y@68525|delta/epsilon subdivisions,2WRMX@28221|Deltaproteobacteria,2MKJ3@213118|Desulfobacterales	28221|Deltaproteobacteria	J	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome	rplW	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02892	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L23
k59_194636_2	926561.KB900620_gene3198	1.9e-50	167.0	COG0090@1|root,COG0090@2|Bacteria,1TP9X@1239|Firmicutes,247XY@186801|Clostridia,3WACR@53433|Halanaerobiales	186801|Clostridia	J	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity	rplB	-	-	ko:K02886	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L2,Ribosomal_L2_C
k59_27849_1	572547.Amico_0549	7.58e-39	138.0	COG1139@1|root,COG1139@2|Bacteria,3TAUE@508458|Synergistetes	508458|Synergistetes	C	PFAM Uncharacterised ACR, YkgG family COG1556	-	-	-	-	-	-	-	-	-	-	-	-	LUD_dom
k59_233548_1	177437.HRM2_34570	8.54e-78	250.0	COG0477@1|root,COG2814@2|Bacteria,1R9V9@1224|Proteobacteria,42Q1C@68525|delta/epsilon subdivisions,2WK7P@28221|Deltaproteobacteria,2MMQA@213118|Desulfobacterales	28221|Deltaproteobacteria	EGP	Major Facilitator Superfamily	-	-	-	ko:K02575	ko00910,map00910	M00615	-	-	ko00000,ko00001,ko00002,ko02000	2.A.1.8	-	-	MFS_1
k59_88921_1	1027273.GZ77_25795	1.59e-124	369.0	COG2801@1|root,COG2801@2|Bacteria,1PBHA@1224|Proteobacteria,1RQ7I@1236|Gammaproteobacteria,1XN8Z@135619|Oceanospirillales	135619|Oceanospirillales	L	Homeodomain-like domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_32,rve
k59_233552_1	96561.Dole_1777	5.13e-62	207.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,2MPSH@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Sigma-54 interaction domain	-	-	-	ko:K07714	ko02020,map02020	M00500	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
k59_203012_1	1192868.CAIU01000023_gene3331	5.39e-107	322.0	COG0677@1|root,COG0677@2|Bacteria,1MUC6@1224|Proteobacteria,2TR5F@28211|Alphaproteobacteria,43I34@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	-	-	1.1.1.136	ko:K13015	ko00520,map00520	-	R00421	RC00291	ko00000,ko00001,ko01000,ko01005	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
k59_142422_1	713586.KB900536_gene241	1.57e-84	271.0	COG3666@1|root,COG3666@2|Bacteria,1N3QR@1224|Proteobacteria,1RR2W@1236|Gammaproteobacteria,1X0AF@135613|Chromatiales	135613|Chromatiales	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_6,DUF772
k59_50812_1	1232437.KL661988_gene188	9.44e-34	129.0	COG1624@1|root,COG1624@2|Bacteria,1PEQT@1224|Proteobacteria,42P5A@68525|delta/epsilon subdivisions,2WKPP@28221|Deltaproteobacteria,2MIQR@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DisA_N,YbbR
k59_142425_1	589865.DaAHT2_0294	4.58e-36	137.0	COG0337@1|root,COG0337@2|Bacteria,1MUBK@1224|Proteobacteria,42MW5@68525|delta/epsilon subdivisions,2WJKR@28221|Deltaproteobacteria,2MIGY@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	-	2.7.1.71,4.2.3.4	ko:K01735,ko:K13829	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412,R03083	RC00002,RC00078,RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase,SKI
k59_179525_1	589865.DaAHT2_0484	1.81e-91	282.0	COG3666@1|root,COG3666@2|Bacteria,1N3QR@1224|Proteobacteria,42N7X@68525|delta/epsilon subdivisions,2WMM9@28221|Deltaproteobacteria,2MMU3@213118|Desulfobacterales	28221|Deltaproteobacteria	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_6,DUF772
k59_149195_2	225937.HP15_2780	2.19e-13	70.5	COG0744@1|root,COG0744@2|Bacteria,1RDAQ@1224|Proteobacteria,1RMGB@1236|Gammaproteobacteria,466WZ@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors	mtgA	GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008955,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016758,GO:0030203,GO:0034645,GO:0042546,GO:0043164,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	2.4.1.129	ko:K03814	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly
k59_88936_1	1211112.ALJC01000127_gene4372	2.97e-18	87.4	COG1804@1|root,COG1804@2|Bacteria,1MU2K@1224|Proteobacteria,1RNB5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	acyl-CoA transferases carnitine dehydratase	coaT	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
k59_36239_2	765869.BDW_02245	6.06e-09	62.8	COG3291@1|root,COG3291@2|Bacteria,1RCXG@1224|Proteobacteria,42SKT@68525|delta/epsilon subdivisions,2X89X@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Mycoplasma protein of unknown function, DUF285	-	-	-	-	-	-	-	-	-	-	-	-	DUF285
k59_157384_1	1499967.BAYZ01000021_gene207	8.18e-15	78.2	2DSRS@1|root,33H75@2|Bacteria	2|Bacteria	S	Curli production assembly/transport component CsgG	-	-	-	-	-	-	-	-	-	-	-	-	CsgG
k59_20479_1	1322246.BN4_10654	5.72e-80	258.0	COG1150@1|root,COG2181@1|root,COG1150@2|Bacteria,COG2181@2|Bacteria,1R44N@1224|Proteobacteria,42NTE@68525|delta/epsilon subdivisions,2WJN8@28221|Deltaproteobacteria,2M8U1@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_17,Fer4_8,Nitrate_red_gam
k59_225217_1	313612.L8106_15335	4.49e-30	123.0	COG0642@1|root,COG2204@1|root,COG2204@2|Bacteria,COG2205@2|Bacteria,1G09B@1117|Cyanobacteria,1H7T9@1150|Oscillatoriales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4118,GAF,GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
k59_149199_1	1121430.JMLG01000022_gene2418	1.42e-14	75.1	COG3829@1|root,COG3829@2|Bacteria,1V0EF@1239|Firmicutes,24DXA@186801|Clostridia	186801|Clostridia	KT	Bacterial regulatory protein, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,PAS_9,Sigma54_activat
k59_210704_1	626939.HMPREF9443_00550	5.64e-46	164.0	COG1207@1|root,COG1207@2|Bacteria,1TP88@1239|Firmicutes,4H30V@909932|Negativicutes	909932|Negativicutes	M	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain	glmU	-	2.3.1.157,2.7.7.23	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00362	R00416,R05332	RC00002,RC00004,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transf_3,NTP_transferase
k59_96676_1	1121405.dsmv_3525	2.2e-28	107.0	2B2GI@1|root,31V1F@2|Bacteria,1RJXV@1224|Proteobacteria,42TBF@68525|delta/epsilon subdivisions,2WP6H@28221|Deltaproteobacteria,2MK5H@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_13679_1	439235.Dalk_3859	7.23e-38	144.0	COG1219@1|root,COG1219@2|Bacteria,1MWIZ@1224|Proteobacteria,42N1Z@68525|delta/epsilon subdivisions,2WJUS@28221|Deltaproteobacteria,2MHMD@213118|Desulfobacterales	28221|Deltaproteobacteria	O	Belongs to the ClpX chaperone family	-	-	-	-	-	-	-	-	-	-	-	-	AAA_2,ClpB_D2-small
k59_111900_1	933262.AXAM01000041_gene1892	5.09e-56	193.0	COG0443@1|root,COG0443@2|Bacteria,1MVEN@1224|Proteobacteria,42M64@68525|delta/epsilon subdivisions,2WIWS@28221|Deltaproteobacteria,2MJ2X@213118|Desulfobacterales	28221|Deltaproteobacteria	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
k59_59110_1	96561.Dole_1037	2.64e-19	91.3	COG4972@1|root,COG4972@2|Bacteria,1MYIB@1224|Proteobacteria,42SIX@68525|delta/epsilon subdivisions,2WP1G@28221|Deltaproteobacteria,2MKAU@213118|Desulfobacterales	28221|Deltaproteobacteria	NU	Fimbrial assembly family protein	gspL	-	-	ko:K02461	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	GspL_C,PilM_2,PilN,T2SSL
k59_96679_1	690850.Desaf_0089	2.2e-96	296.0	COG0364@1|root,COG0364@2|Bacteria,1MUN0@1224|Proteobacteria,42M0J@68525|delta/epsilon subdivisions,2WK1D@28221|Deltaproteobacteria,2M9K4@213115|Desulfovibrionales	28221|Deltaproteobacteria	G	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone	zwf	-	1.1.1.363,1.1.1.49	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	M00004,M00006,M00008	R00835,R02736,R10907	RC00001,RC00066	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	G6PD_C,G6PD_N
k59_13684_1	1121413.JMKT01000012_gene650	5.14e-70	226.0	COG3259@1|root,COG3259@2|Bacteria,1QUQ7@1224|Proteobacteria,42RHV@68525|delta/epsilon subdivisions,2WNH5@28221|Deltaproteobacteria,2MA5W@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	Nickel-dependent hydrogenase	hyhL	-	-	-	-	-	-	-	-	-	-	-	NiFeSe_Hases
k59_65925_1	335543.Sfum_1940	6.75e-92	272.0	COG1143@1|root,COG1143@2|Bacteria,1MV90@1224|Proteobacteria,42R5T@68525|delta/epsilon subdivisions,2WMVQ@28221|Deltaproteobacteria,2MRW5@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoI	-	1.6.5.3	ko:K00338	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer4
k59_4733_1	626887.J057_11271	2.67e-20	93.6	28HC9@1|root,2Z7P5@2|Bacteria,1R4BH@1224|Proteobacteria,1RSAN@1236|Gammaproteobacteria,4642U@72275|Alteromonadaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_4733_2	690850.Desaf_2363	5.7e-22	92.4	28I6Z@1|root,2Z89U@2|Bacteria,1R8YM@1224|Proteobacteria	1224|Proteobacteria	S	von Willebrand factor (vWF) type A domain	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_210716_1	1232437.KL662050_gene5290	2.65e-54	187.0	COG2204@1|root,COG5000@1|root,COG2204@2|Bacteria,COG5000@2|Bacteria,1RBB9@1224|Proteobacteria,42R73@68525|delta/epsilon subdivisions,2WMPX@28221|Deltaproteobacteria,2MMXA@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Histidine kinase-like ATPases	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,Response_reg
k59_210716_2	243231.GSU1555	1.07e-13	71.6	COG3829@1|root,COG4191@1|root,COG3829@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MC4@68525|delta/epsilon subdivisions,2WIU5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	5TM-5TMR_LYT,GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
k59_164485_2	1121405.dsmv_2548	7.82e-07	50.4	COG2896@1|root,COG2896@2|Bacteria,1MXMH@1224|Proteobacteria,42NTM@68525|delta/epsilon subdivisions,2WKIQ@28221|Deltaproteobacteria,2MPJN@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Radical SAM superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
k59_188137_1	1232453.BAIF02000135_gene1598	1.31e-47	169.0	COG2801@1|root,COG2801@2|Bacteria	2|Bacteria	L	transposition	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_28,HTH_32,LZ_Tnp_IS481,rve,rve_3
k59_104409_1	439235.Dalk_3701	3.02e-31	125.0	COG0457@1|root,COG0683@1|root,COG0457@2|Bacteria,COG0683@2|Bacteria,1R8IG@1224|Proteobacteria,42N7H@68525|delta/epsilon subdivisions,2WIUQ@28221|Deltaproteobacteria,2MHTC@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Periplasmic binding protein	-	-	-	ko:K07121	-	-	-	-	ko00000	-	-	-	LppC,Peripla_BP_6,TPR_16,TPR_6
k59_111929_1	1151119.KB895499_gene3690	2.1e-07	59.7	COG2358@1|root,COG2358@2|Bacteria,2GKQJ@201174|Actinobacteria	201174|Actinobacteria	S	TRAP transporter solute receptor TAXI family	-	-	-	ko:K07080	-	-	-	-	ko00000	-	-	-	NMT1_3
k59_20502_1	1463936.JOJI01000018_gene7665	1.09e-09	60.1	COG0509@1|root,COG0509@2|Bacteria,2IKN2@201174|Actinobacteria	201174|Actinobacteria	E	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein	gcvH	-	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	-	GCV_H
k59_127213_1	247490.KSU1_B0406	2.83e-90	277.0	arCOG06766@1|root,2Z87F@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_13693_1	1121396.KB893118_gene3101	7.52e-128	378.0	COG1032@1|root,COG1032@2|Bacteria,1MY2Y@1224|Proteobacteria,42NG3@68525|delta/epsilon subdivisions,2WJ95@28221|Deltaproteobacteria,2MJ57@213118|Desulfobacterales	28221|Deltaproteobacteria	C	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,DUF4070,Radical_SAM
k59_142460_1	28229.ND2E_3441	7e-34	123.0	COG1196@1|root,COG1196@2|Bacteria,1NK8W@1224|Proteobacteria,1SGJD@1236|Gammaproteobacteria	1236|Gammaproteobacteria	D	DNA N-6-adenine-methyltransferase (Dam)	-	-	-	-	-	-	-	-	-	-	-	-	Dam
k59_213584_1	1167006.UWK_00025	9.94e-66	214.0	COG0402@1|root,COG0402@2|Bacteria,1MVPA@1224|Proteobacteria,42NI6@68525|delta/epsilon subdivisions,2WKI1@28221|Deltaproteobacteria,2MJDX@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine	mtaD	-	3.5.4.28,3.5.4.31	ko:K12960	ko00270,ko01100,map00270,map01100	-	R09660	RC00477	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
k59_122700_1	1094466.KQS_01445	2.05e-15	79.3	COG4974@1|root,COG4974@2|Bacteria,4NGE1@976|Bacteroidetes,1HY1D@117743|Flavobacteriia,2NSBS@237|Flavobacterium	976|Bacteroidetes	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
k59_198428_1	555779.Dthio_PD0866	3.09e-19	84.0	COG1738@1|root,COG1738@2|Bacteria,1RJV6@1224|Proteobacteria,43BF6@68525|delta/epsilon subdivisions,2X6TJ@28221|Deltaproteobacteria,2MH6P@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage	-	-	-	ko:K09125	-	-	-	-	ko00000	-	-	-	Vut_1
k59_198428_2	1121438.JNJA01000010_gene1942	6.68e-42	142.0	COG0780@1|root,COG0780@2|Bacteria,1MW0M@1224|Proteobacteria,42TKK@68525|delta/epsilon subdivisions,2X5NX@28221|Deltaproteobacteria,2MGTN@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)	queF	-	1.7.1.13	ko:K09457	ko00790,ko01100,map00790,map01100	-	R07605	RC01875	ko00000,ko00001,ko01000,ko03016	-	-	-	QueF
k59_1290_1	247490.KSU1_C1354	1.39e-41	164.0	COG3850@1|root,COG3852@1|root,COG4191@1|root,COG3850@2|Bacteria,COG3852@2|Bacteria,COG4191@2|Bacteria,2J2AR@203682|Planctomycetes	203682|Planctomycetes	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HAMP,HATPase_c,HisKA,PAS_9
k59_213593_1	768706.Desor_1620	9.33e-77	238.0	COG0441@1|root,COG0441@2|Bacteria,1V041@1239|Firmicutes,24BS9@186801|Clostridia,261EI@186807|Peptococcaceae	186801|Clostridia	J	PFAM tRNA synthetase class II	-	-	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2d
k59_84644_2	768704.Desmer_3258	1.55e-101	302.0	COG0500@1|root,COG2226@2|Bacteria,1UWCG@1239|Firmicutes,25KSV@186801|Clostridia,266DB@186807|Peptococcaceae	186801|Clostridia	Q	Methylase involved in ubiquinone menaquinone biosynthesis	-	-	-	ko:K15256	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_25
k59_84644_3	1121943.KB899997_gene1708	4.44e-08	53.9	COG0473@1|root,COG0473@2|Bacteria,1MUH4@1224|Proteobacteria,1RRPI@1236|Gammaproteobacteria,1XNNF@135619|Oceanospirillales	135619|Oceanospirillales	CE	Tartrate dehydrogenase	tdh	-	1.1.1.83,1.1.1.93,4.1.1.73	ko:K07246	ko00630,ko00650,map00630,map00650	-	R00215,R01751,R02545,R06180	RC00084,RC00105,RC00594	ko00000,ko00001,ko01000	-	-	-	Iso_dh
k59_130328_1	596151.DesfrDRAFT_4009	8.25e-14	75.5	COG0038@1|root,COG0517@1|root,COG0038@2|Bacteria,COG0517@2|Bacteria,1MV4K@1224|Proteobacteria,42N93@68525|delta/epsilon subdivisions,2WJ9N@28221|Deltaproteobacteria,2M9G4@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	PFAM Cl- channel voltage-gated family protein	-	-	-	ko:K03281	-	-	-	-	ko00000	2.A.49	-	-	CBS,Voltage_CLC
k59_130328_2	266779.Meso_1466	1.77e-23	93.2	COG4274@1|root,COG4274@2|Bacteria,1N29P@1224|Proteobacteria,2UD2U@28211|Alphaproteobacteria,43QUM@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	GYD domain	-	-	-	-	-	-	-	-	-	-	-	-	GYD
k59_175768_1	1123504.JQKD01000008_gene5428	0.000959	47.0	COG3501@1|root,COG3501@2|Bacteria,1MU7Q@1224|Proteobacteria,2VJDF@28216|Betaproteobacteria,4ACY7@80864|Comamonadaceae	28216|Betaproteobacteria	U	Rhs element Vgr protein	-	-	-	ko:K11904	ko03070,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	Gp5_C,Phage_GPD
k59_175769_1	1121405.dsmv_1665	2.15e-106	320.0	COG5557@1|root,COG5557@2|Bacteria,1PFX4@1224|Proteobacteria,42PIE@68525|delta/epsilon subdivisions,2WM3C@28221|Deltaproteobacteria,2MMPY@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Polysulphide reductase, NrfD	moz	-	-	ko:K00185	-	-	-	-	ko00000	5.A.3	-	-	DUF3341,NrfD
k59_175769_2	1121920.AUAU01000026_gene1441	3.51e-10	65.9	COG2010@1|root,COG2010@2|Bacteria,3Y3HF@57723|Acidobacteria	57723|Acidobacteria	C	Protein of unknown function (DUF3341)	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3,DUF3341
k59_130343_1	335543.Sfum_0367	1.13e-95	290.0	COG0192@1|root,COG0192@2|Bacteria,1MUFQ@1224|Proteobacteria,42MFM@68525|delta/epsilon subdivisions,2WIQ3@28221|Deltaproteobacteria,2MQ9B@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
k59_198453_1	398580.Dshi_1678	1.16e-19	88.2	2CDFF@1|root,32RXP@2|Bacteria,1N26W@1224|Proteobacteria,2UDNJ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_137902_1	1121918.ARWE01000001_gene500	1.03e-113	346.0	COG4585@1|root,COG4585@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
k59_137902_2	1121918.ARWE01000001_gene501	2.8e-14	69.7	COG2197@1|root,COG2197@2|Bacteria,1RGXD@1224|Proteobacteria,43AY7@68525|delta/epsilon subdivisions,2X6CK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
k59_198462_1	439235.Dalk_5180	9.06e-137	397.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,42MK5@68525|delta/epsilon subdivisions,2WJ3Z@28221|Deltaproteobacteria,2MIMJ@213118|Desulfobacterales	28221|Deltaproteobacteria	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
k59_236479_1	329726.AM1_5416	2.47e-36	129.0	COG1943@1|root,COG1943@2|Bacteria,1G9TK@1117|Cyanobacteria	1117|Cyanobacteria	L	PFAM Transposase IS200 like	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
k59_206138_1	335543.Sfum_0245	7.84e-29	106.0	COG3357@1|root,COG3357@2|Bacteria,1N7JG@1224|Proteobacteria,42VEP@68525|delta/epsilon subdivisions,2WRD7@28221|Deltaproteobacteria,2MQP0@213462|Syntrophobacterales	28221|Deltaproteobacteria	K	transcriptional regulator containing an HTH domain fused to a Zn-ribbon	-	-	-	ko:K07743	-	-	-	-	ko00000	-	-	-	HTH_5
k59_54431_1	288000.BBta_0440	6.77e-23	90.1	COG2963@1|root,COG2963@2|Bacteria,1RGZ5@1224|Proteobacteria,2UAIS@28211|Alphaproteobacteria,3K1PX@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	L	Transposase	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_Tnp_1
k59_54431_2	1096546.WYO_5544	5.2e-68	213.0	COG2801@1|root,COG2801@2|Bacteria,1MVN5@1224|Proteobacteria,2TQK0@28211|Alphaproteobacteria,1JTSW@119045|Methylobacteriaceae	28211|Alphaproteobacteria	L	PFAM Integrase catalytic region	-	-	-	-	-	-	-	-	-	-	-	-	HTH_21,rve,rve_3
k59_153114_2	1121428.DESHY_60303___1	4.07e-28	107.0	COG1051@1|root,COG1051@2|Bacteria,1UIGB@1239|Firmicutes,24QBF@186801|Clostridia	186801|Clostridia	F	pfam nudix	-	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
k59_39332_1	258052.JNYV01000006_gene2663	1.06e-66	213.0	COG0560@1|root,COG0560@2|Bacteria,2GKRQ@201174|Actinobacteria	201174|Actinobacteria	E	haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD
k59_8940_1	1121405.dsmv_2731	3.4e-85	265.0	COG0195@1|root,COG0195@2|Bacteria,1MWT7@1224|Proteobacteria,42MUW@68525|delta/epsilon subdivisions,2WIXI@28221|Deltaproteobacteria,2MHW6@213118|Desulfobacterales	28221|Deltaproteobacteria	K	Participates in both transcription termination and antitermination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	HHH_5,KH_5,NusA_N,S1
k59_115001_1	1487923.DP73_04875	1.19e-37	140.0	COG0517@1|root,COG0517@2|Bacteria,1TQ4J@1239|Firmicutes,24B68@186801|Clostridia,260BK@186807|Peptococcaceae	186801|Clostridia	S	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	Y2_Tnp,Zn_Tnp_IS91
k59_8947_1	1123376.AUIU01000014_gene579	8.06e-50	171.0	COG0564@1|root,COG0564@2|Bacteria,3J0HF@40117|Nitrospirae	40117|Nitrospirae	J	Responsible for synthesis of pseudouridine from uracil	-	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
k59_84675_1	1121403.AUCV01000003_gene1794	2.69e-12	65.5	COG1100@1|root,COG1100@2|Bacteria,1R6NS@1224|Proteobacteria,42NIX@68525|delta/epsilon subdivisions,2WJ44@28221|Deltaproteobacteria,2MI9K@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Gtr1/RagA G protein conserved region	mglA	GO:0008150,GO:0032879,GO:0032880,GO:0050789,GO:0065007	-	ko:K06883	-	-	-	-	ko00000	-	-	-	Arf,Ras
k59_168060_1	96561.Dole_2108	8.03e-71	226.0	COG1234@1|root,COG1234@2|Bacteria,1PPRD@1224|Proteobacteria,42N8A@68525|delta/epsilon subdivisions,2WKHD@28221|Deltaproteobacteria,2MIHV@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Beta-lactamase superfamily domain	-	-	3.1.26.11	ko:K00784	ko03013,map03013	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	Lactamase_B_2
k59_115003_1	933262.AXAM01000010_gene1402	6.55e-56	184.0	COG0484@1|root,COG0705@1|root,COG0484@2|Bacteria,COG0705@2|Bacteria,1MYFP@1224|Proteobacteria,42P0V@68525|delta/epsilon subdivisions,2WJGR@28221|Deltaproteobacteria,2MI6P@213118|Desulfobacterales	28221|Deltaproteobacteria	O	Rhomboid family	-	-	-	ko:K07059	-	-	-	-	ko00000	-	-	-	DnaJ_C,Rhomboid
k59_115003_2	748247.AZKH_p0081	3.22e-21	91.3	COG2084@1|root,COG2084@2|Bacteria,1P0X0@1224|Proteobacteria,2VS06@28216|Betaproteobacteria	28216|Betaproteobacteria	I	6-phosphogluconate dehydrogenase, NAD-binding	-	-	1.1.1.31	ko:K00020	ko00280,ko01100,map00280,map01100	-	R05066	RC00099	ko00000,ko00001,ko01000	-	-	-	NAD_binding_11,NAD_binding_2
k59_84677_1	1121447.JONL01000001_gene1111	4.67e-22	99.8	COG3437@1|root,COG3437@2|Bacteria,1NDRJ@1224|Proteobacteria,42TDX@68525|delta/epsilon subdivisions,2WV2R@28221|Deltaproteobacteria,2M9V2@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
k59_130375_1	1121403.AUCV01000025_gene2298	4.24e-87	282.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42R36@68525|delta/epsilon subdivisions,2WU0Z@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	frzCD	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal,PAS_4,PAS_9,dCache_1,sCache_3_2,sCache_3_3
k59_153135_1	439235.Dalk_4377	4.78e-33	118.0	2EDMA@1|root,337H4@2|Bacteria,1N9ES@1224|Proteobacteria,42VB1@68525|delta/epsilon subdivisions,2WRQZ@28221|Deltaproteobacteria,2MKGP@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_77337_1	43989.cce_1174	2.25e-12	70.9	COG0125@1|root,COG0125@2|Bacteria,1G5JT@1117|Cyanobacteria,3KHQU@43988|Cyanothece	1117|Cyanobacteria	F	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	tmk	GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylate_kin
k59_221388_1	999419.HMPREF1077_03498	5.82e-59	198.0	COG1069@1|root,COG1069@2|Bacteria,4NEFQ@976|Bacteroidetes,2FNNI@200643|Bacteroidia,22X1M@171551|Porphyromonadaceae	976|Bacteroidetes	G	FGGY family of carbohydrate kinases, N-terminal domain	araB	-	2.7.1.16	ko:K00853	ko00040,ko01100,map00040,map01100	-	R01526,R02439	RC00002,RC00538	ko00000,ko00001,ko01000	-	-	-	FGGY_C,FGGY_N
k59_54448_1	991.IW20_20160	3.48e-34	131.0	COG0626@1|root,COG0626@2|Bacteria,4NF4W@976|Bacteroidetes,1HWS8@117743|Flavobacteriia,2NSUB@237|Flavobacterium	976|Bacteroidetes	E	Cystathionine beta-lyase	-	-	4.4.1.11	ko:K01761	ko00270,ko00450,map00270,map00450	-	R00654,R04770	RC00196,RC00348,RC01209,RC01210	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
k59_92298_1	1120963.KB894491_gene1062	1.15e-51	171.0	COG0204@1|root,COG0204@2|Bacteria	2|Bacteria	I	Acyl-transferase	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
k59_115009_1	1045855.DSC_00315	1.27e-10	65.9	COG1028@1|root,COG1028@2|Bacteria,1MUUV@1224|Proteobacteria,1RMJU@1236|Gammaproteobacteria,1X51Z@135614|Xanthomonadales	135614|Xanthomonadales	IQ	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	-	-	1.5.1.33	ko:K03793	-	-	-	-	ko00000,ko01000	-	-	-	adh_short_C2
k59_8953_1	643562.Daes_0386	3.41e-36	136.0	COG3464@1|root,COG3464@2|Bacteria,1MV5J@1224|Proteobacteria,42M93@68525|delta/epsilon subdivisions,2WK5I@28221|Deltaproteobacteria,2MBEI@213115|Desulfovibrionales	28221|Deltaproteobacteria	L	PFAM Transposase, IS204 IS1001 IS1096 IS1165	-	-	-	ko:K07485	-	-	-	-	ko00000	-	-	-	DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3
k59_24164_1	1201293.AKXQ01000022_gene425	1.25e-84	269.0	COG0277@1|root,COG0277@2|Bacteria,1MXTV@1224|Proteobacteria,1RRN8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	COG0277 FAD FMN-containing dehydrogenases	ygcU	-	2.5.1.26	ko:K00803	ko00565,ko01100,ko04146,map00565,map01100,map04146	-	R04311	RC00020,RC02886	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
k59_138455_1	1121405.dsmv_1468	4.57e-58	190.0	COG0697@1|root,COG0697@2|Bacteria,1N024@1224|Proteobacteria,42NW9@68525|delta/epsilon subdivisions,2WJEJ@28221|Deltaproteobacteria,2MJ3K@213118|Desulfobacterales	28221|Deltaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
k59_62650_1	34007.IT40_09095	2.46e-15	77.0	COG0145@1|root,COG0145@2|Bacteria,1MU2Y@1224|Proteobacteria,2TQZ6@28211|Alphaproteobacteria,2PVBA@265|Paracoccus	28211|Alphaproteobacteria	EQ	Hydantoinase/oxoprolinase N-terminal region	-	-	3.5.2.14	ko:K01473	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydant_A_N,Hydantoinase_A
k59_62650_2	706587.Desti_1840	1.91e-27	110.0	COG1529@1|root,COG1529@2|Bacteria,1MUEA@1224|Proteobacteria,42MER@68525|delta/epsilon subdivisions,2WIYV@28221|Deltaproteobacteria,2MR87@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	aldehyde oxidase and xanthine dehydrogenase, a b hammerhead	-	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
k59_39837_1	439235.Dalk_0047	3.46e-107	323.0	COG2239@1|root,COG2239@2|Bacteria,1MW24@1224|Proteobacteria,42MA7@68525|delta/epsilon subdivisions,2WIPC@28221|Deltaproteobacteria,2MI8B@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Acts as a magnesium transporter	-	-	-	ko:K06213	-	-	-	-	ko00000,ko02000	1.A.26.1	-	-	CBS,MgtE,MgtE_N
k59_130858_1	439235.Dalk_5241	6.68e-10	56.6	COG3436@1|root,COG3436@2|Bacteria,1MZFT@1224|Proteobacteria,42URZ@68525|delta/epsilon subdivisions,2WQ58@28221|Deltaproteobacteria,2MKGK@213118|Desulfobacterales	28221|Deltaproteobacteria	L	PFAM IS66 Orf2 like protein	-	-	-	ko:K07484	-	-	-	-	ko00000	-	-	-	TnpB_IS66
k59_236936_1	323848.Nmul_A2249	2.01e-26	98.6	COG3360@1|root,COG3360@2|Bacteria,1PW6C@1224|Proteobacteria,2VXDE@28216|Betaproteobacteria,373H6@32003|Nitrosomonadales	28216|Betaproteobacteria	S	Dodecin	-	-	-	ko:K09165	-	-	-	-	ko00000	-	-	-	Dodecin
k59_32145_1	935567.JAES01000003_gene234	1.42e-84	262.0	COG1960@1|root,COG1960@2|Bacteria,1MUK0@1224|Proteobacteria,1RNBX@1236|Gammaproteobacteria,1X45S@135614|Xanthomonadales	135614|Xanthomonadales	I	Acyl-CoA dehydrogenase	gcdH	-	1.3.8.6	ko:K00252	ko00071,ko00310,ko00362,ko00380,ko01100,ko01120,ko01130,map00071,map00310,map00362,map00380,map01100,map01120,map01130	M00032	R02487,R02488,R10074	RC00052,RC00156	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
k59_214080_1	933262.AXAM01000073_gene3360	6.61e-108	318.0	COG0159@1|root,COG0159@2|Bacteria,1MXJV@1224|Proteobacteria,42N5B@68525|delta/epsilon subdivisions,2WJX4@28221|Deltaproteobacteria,2MIHZ@213118|Desulfobacterales	28221|Deltaproteobacteria	E	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate	trpA	-	4.2.1.20	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_syntA
k59_214080_2	1214242.B446_10680	4.38e-14	73.2	COG0133@1|root,COG0133@2|Bacteria,2GM7Z@201174|Actinobacteria	201174|Actinobacteria	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB	GO:0000162,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.2.1.20	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
k59_153752_1	1232437.KL662077_gene1888	3.08e-35	130.0	COG1902@1|root,COG1902@2|Bacteria,1MVE0@1224|Proteobacteria,42NA7@68525|delta/epsilon subdivisions,2WIN5@28221|Deltaproteobacteria,2MJ30@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM NADH flavin oxidoreductase NADH oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_FMN
k59_92770_2	1121434.AULY01000006_gene748	4.77e-38	137.0	COG3383@1|root,COG3383@2|Bacteria,1QTZB@1224|Proteobacteria,43BP2@68525|delta/epsilon subdivisions,2WK8X@28221|Deltaproteobacteria,2MGYP@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	NADH-ubiquinone oxidoreductase-G iron-sulfur binding region	-	-	-	-	-	-	-	-	-	-	-	-	Fer2_4,Fer4_7,Molybdop_Fe4S4,Molybdopterin,NADH-G_4Fe-4S_3
k59_62655_1	1048983.EL17_01580	6.08e-80	255.0	COG1236@1|root,COG1236@2|Bacteria,4NESD@976|Bacteroidetes,47K9F@768503|Cytophagia	976|Bacteroidetes	J	exonuclease of the beta-lactamase fold involved in RNA processing	-	-	-	ko:K07576	-	-	-	-	ko00000	-	-	-	Beta-Casp,Lactamase_B,Lactamase_B_6,RMMBL
k59_100529_1	573370.DMR_34290	3.65e-93	277.0	COG0479@1|root,COG0479@2|Bacteria,1MVHS@1224|Proteobacteria,42M2J@68525|delta/epsilon subdivisions,2WJMH@28221|Deltaproteobacteria,2M84J@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein	sdhB	-	1.3.5.1,1.3.5.4	ko:K00240,ko:K00245	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	M00009,M00011,M00149,M00150,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_3,Fer4_10,Fer4_8
k59_199044_1	592316.Pat9b_0591	0.000244	49.3	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,3W0HW@53335|Pantoea	1236|Gammaproteobacteria	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal
k59_16906_1	1121405.dsmv_2921	8.93e-66	220.0	COG0493@1|root,COG2878@1|root,COG0493@2|Bacteria,COG2878@2|Bacteria,1NZIR@1224|Proteobacteria,42MPF@68525|delta/epsilon subdivisions,2X5BJ@28221|Deltaproteobacteria,2MISB@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Putative Fe-S cluster	-	-	-	-	-	-	-	-	-	-	-	-	FeS,Fer4,Fer4_20,Fer4_9,Pyr_redox_2
k59_77861_2	335543.Sfum_1609	1.02e-122	368.0	COG1530@1|root,COG1530@2|Bacteria,1MV65@1224|Proteobacteria,42M5E@68525|delta/epsilon subdivisions,2WIV6@28221|Deltaproteobacteria,2MQAN@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	TIGRFAM ribonuclease, Rne Rng family	cafA	-	3.1.26.12	ko:K08300,ko:K08301	ko03018,map03018	M00394	-	-	ko00000,ko00001,ko00002,ko01000,ko03009,ko03019	-	-	-	RNase_E_G,S1
k59_92777_1	335543.Sfum_3475	1.82e-72	237.0	COG1032@1|root,COG1032@2|Bacteria,1MU15@1224|Proteobacteria,42N12@68525|delta/epsilon subdivisions,2WK0X@28221|Deltaproteobacteria,2MRDF@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	PFAM Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
k59_239087_2	768704.Desmer_4478	7.28e-47	159.0	COG3723@1|root,COG3723@2|Bacteria,1UNDF@1239|Firmicutes,24ECD@186801|Clostridia	186801|Clostridia	L	RecT family	-	-	-	ko:K07455	-	-	-	-	ko00000,ko03400	-	-	-	RecT
k59_232319_1	1040989.AWZU01000007_gene719	3.2e-59	192.0	COG1225@1|root,COG1225@2|Bacteria,1MWFZ@1224|Proteobacteria,2TRJM@28211|Alphaproteobacteria,3JTTW@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	O	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
k59_126102_1	177437.HRM2_21630	5.7e-49	172.0	COG0427@1|root,COG1670@1|root,COG0427@2|Bacteria,COG1670@2|Bacteria,1MUGE@1224|Proteobacteria,42MHC@68525|delta/epsilon subdivisions,2WINZ@28221|Deltaproteobacteria,2MJ4K@213118|Desulfobacterales	28221|Deltaproteobacteria	CK	PFAM Acetyl-CoA hydrolase transferase	-	-	-	-	-	-	-	-	-	-	-	-	AcetylCoA_hyd_C,AcetylCoA_hydro,Acetyltransf_1
k59_103228_1	1121405.dsmv_1427	2.4e-77	239.0	COG2836@1|root,COG2836@2|Bacteria,1PJER@1224|Proteobacteria,43EBU@68525|delta/epsilon subdivisions,2X2D4@28221|Deltaproteobacteria,2MMFS@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Cytochrome C biogenesis protein transmembrane region	-	-	-	ko:K09792	-	-	-	-	ko00000	-	-	-	DsbD_2
k59_209537_1	439235.Dalk_1568	1.25e-79	249.0	COG1148@1|root,COG1148@2|Bacteria,1Q0ZF@1224|Proteobacteria,42NHH@68525|delta/epsilon subdivisions,2WJ6M@28221|Deltaproteobacteria,2MIS1@213118|Desulfobacterales	28221|Deltaproteobacteria	C	FAD dependent oxidoreductase	qmoA	-	-	ko:K16885	-	-	-	-	ko00000	-	-	-	FAD_oxidored,NAD_binding_8,Pyr_redox_2
k59_126104_1	1304885.AUEY01000052_gene1553	5.75e-34	124.0	2CIGB@1|root,32TRQ@2|Bacteria,1N6CT@1224|Proteobacteria,42UF7@68525|delta/epsilon subdivisions,2WR4N@28221|Deltaproteobacteria,2MKHP@213118|Desulfobacterales	28221|Deltaproteobacteria	S	PilZ domain	-	-	-	-	-	-	-	-	-	-	-	-	PilZ
k59_163402_1	314271.RB2654_20383	9.85e-06	53.5	COG1233@1|root,COG1233@2|Bacteria,1MV2R@1224|Proteobacteria,2TSR0@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	Phytoene dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase,NAD_binding_8
k59_72902_1	526222.Desal_0482	1.78e-41	143.0	COG4577@1|root,COG4577@2|Bacteria,1R55P@1224|Proteobacteria,42RUF@68525|delta/epsilon subdivisions,2WNT1@28221|Deltaproteobacteria,2MB2A@213115|Desulfovibrionales	28221|Deltaproteobacteria	CQ	BMC	-	-	-	-	-	-	-	-	-	-	-	-	BMC
k59_72902_2	350688.Clos_2393	5.61e-35	130.0	COG4820@1|root,COG4820@2|Bacteria,1TQVV@1239|Firmicutes,249HD@186801|Clostridia,36E4Y@31979|Clostridiaceae	186801|Clostridia	E	Ethanolamine utilization protein EutJ	eutJ	-	-	ko:K04024	-	-	-	-	ko00000	-	-	-	MreB_Mbl,PilM_2
k59_148052_1	933262.AXAM01000004_gene2405	1.07e-103	318.0	COG1154@1|root,COG1154@2|Bacteria,1MUSJ@1224|Proteobacteria,42M35@68525|delta/epsilon subdivisions,2WIX5@28221|Deltaproteobacteria,2MI30@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)	dxs	-	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	-	DXP_synthase_N,Transket_pyr,Transketolase_C
k59_49803_1	744872.Spica_2234	1.71e-33	127.0	COG0123@1|root,COG0123@2|Bacteria,2J9NT@203691|Spirochaetes	203691|Spirochaetes	BQ	Histone deacetylase domain	-	-	-	-	-	-	-	-	-	-	-	-	Hist_deacetyl
k59_126125_1	583355.Caka_1597	3.6e-83	258.0	COG0668@1|root,COG0668@2|Bacteria,46UFI@74201|Verrucomicrobia,3K8BZ@414999|Opitutae	414999|Opitutae	M	mechanosensitive ion channel	-	-	-	ko:K16052	-	-	-	-	ko00000,ko02000	1.A.23.4	-	-	MS_channel
k59_163416_1	1232410.KI421421_gene3337	2.85e-14	73.2	COG0168@1|root,COG0168@2|Bacteria,1MUIJ@1224|Proteobacteria,42YBV@68525|delta/epsilon subdivisions,2WTTU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Cation transport protein	-	-	-	-	-	-	-	-	-	-	-	-	TrkH
k59_163416_2	1121405.dsmv_1645	1.15e-24	95.9	2DNS2@1|root,32YVY@2|Bacteria,1N9QQ@1224|Proteobacteria,42X5E@68525|delta/epsilon subdivisions,2WSAR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_148059_1	643562.Daes_1946	1.49e-64	206.0	COG1149@1|root,COG1149@2|Bacteria,1NCD9@1224|Proteobacteria,42PHV@68525|delta/epsilon subdivisions,2WKDZ@28221|Deltaproteobacteria,2M8KV@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	PFAM Cobyrinic acid ac-diamide synthase	-	-	-	-	-	-	-	-	-	-	-	-	CbiA,Fer4
k59_64858_1	706587.Desti_3169	8.95e-18	82.4	COG0683@1|root,COG0683@2|Bacteria,1MXPJ@1224|Proteobacteria,42NFF@68525|delta/epsilon subdivisions,2WKDK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Amino acid amide ABC transporter substrate-binding protein, HAAT family	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
k59_232340_1	118005.AWNK01000013_gene890	1.46e-57	198.0	COG4974@1|root,COG4974@2|Bacteria	2|Bacteria	L	Belongs to the 'phage' integrase family	-	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_4,Phage_integrase
k59_232340_2	913865.DOT_3301	9.15e-73	239.0	COG0517@1|root,COG0517@2|Bacteria,1TQ4J@1239|Firmicutes,24B68@186801|Clostridia,260BK@186807|Peptococcaceae	186801|Clostridia	S	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	Y2_Tnp,Zn_Tnp_IS91
k59_193616_1	1499967.BAYZ01000154_gene1444	1.05e-52	172.0	COG2080@1|root,COG2080@2|Bacteria,2NPPX@2323|unclassified Bacteria	2|Bacteria	C	PFAM 2Fe-2S -binding	-	-	1.2.5.3,1.3.99.16	ko:K03518,ko:K07302	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Fer2,Fer2_2
k59_49810_1	1121405.dsmv_3269	3.15e-103	314.0	COG0706@1|root,COG0706@2|Bacteria,1MV5M@1224|Proteobacteria,42MS8@68525|delta/epsilon subdivisions,2WJB6@28221|Deltaproteobacteria,2MJ96@213118|Desulfobacterales	28221|Deltaproteobacteria	U	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins	yidC	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP,YidC_periplas
k59_216679_1	1232437.KL661956_gene2429	5.88e-52	166.0	COG5561@1|root,COG5561@2|Bacteria,1RH81@1224|Proteobacteria,42SY4@68525|delta/epsilon subdivisions,2WPAG@28221|Deltaproteobacteria,2MK3G@213118|Desulfobacterales	28221|Deltaproteobacteria	S	CGGC	-	-	-	-	-	-	-	-	-	-	-	-	CGGC
k59_187301_1	690850.Desaf_0688	3.82e-26	109.0	COG2369@1|root,COG2369@2|Bacteria,1R40R@1224|Proteobacteria,42P0H@68525|delta/epsilon subdivisions,2WJK7@28221|Deltaproteobacteria,2MGMC@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Phage Mu protein F like protein	-	-	-	-	-	-	-	-	-	-	-	-	Phage_Mu_F
k59_163771_1	335543.Sfum_3753	8.88e-49	166.0	COG0826@1|root,COG0826@2|Bacteria,1N4QJ@1224|Proteobacteria,42YJR@68525|delta/epsilon subdivisions,2WUQ1@28221|Deltaproteobacteria,2MR6V@213462|Syntrophobacterales	28221|Deltaproteobacteria	O	Peptidase family U32	-	-	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_U32
k59_118112_1	335543.Sfum_0110	3.26e-107	329.0	COG4198@1|root,COG4198@2|Bacteria,1NPPY@1224|Proteobacteria,42NTB@68525|delta/epsilon subdivisions,2WKNX@28221|Deltaproteobacteria,2MQH0@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF1015)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1015
k59_58255_1	335543.Sfum_2525	4.79e-13	73.6	COG0568@1|root,COG0568@2|Bacteria,1MXGX@1224|Proteobacteria,42PIS@68525|delta/epsilon subdivisions,2WKSS@28221|Deltaproteobacteria,2MQYD@213462|Syntrophobacterales	28221|Deltaproteobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	-	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
k59_103592_2	491915.Aflv_2449	4.4e-41	145.0	COG2801@1|root,COG2801@2|Bacteria,1TU21@1239|Firmicutes,4HDK4@91061|Bacilli	91061|Bacilli	L	COG2801 Transposase and inactivated derivatives	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve
k59_65232_2	1123242.JH636434_gene5037	2.07e-14	73.9	COG2993@1|root,COG2993@2|Bacteria,2IYKY@203682|Planctomycetes	203682|Planctomycetes	C	PFAM cytochrome C oxidase mono-heme subunit FixO	-	-	-	-	-	-	-	-	-	-	-	-	FixO
k59_217048_1	1379858.N508_01619	4.05e-12	63.2	COG5336@1|root,COG5336@2|Bacteria,2GG0Q@200930|Deferribacteres	200930|Deferribacteres	S	Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter	-	-	-	ko:K02116	-	-	-	-	ko00000,ko00194	3.A.2.1	-	-	ATPase_gene1
k59_27112_1	1121022.ABENE_13040	1.21e-24	105.0	COG5659@1|root,COG5659@2|Bacteria,1MWAV@1224|Proteobacteria,2U2Q3@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_5
k59_232815_2	690850.Desaf_2573	4.24e-140	409.0	COG3119@1|root,COG3119@2|Bacteria,1MUJH@1224|Proteobacteria,42Q8I@68525|delta/epsilon subdivisions,2X5IX@28221|Deltaproteobacteria,2MA7R@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	Sulfatase	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase,Sulfatase_C
k59_171717_1	767817.Desgi_4248	3.95e-36	137.0	COG3829@1|root,COG3829@2|Bacteria	2|Bacteria	T	transcription factor binding	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,PAS_4,PAS_9,Sigma54_activat
k59_134034_2	1121918.ARWE01000001_gene2577	3.57e-57	185.0	COG0745@1|root,COG0745@2|Bacteria,1MU67@1224|Proteobacteria,42N90@68525|delta/epsilon subdivisions,2WJUU@28221|Deltaproteobacteria,43SE9@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
k59_193962_1	314278.NB231_10163	8.37e-12	62.8	2CNK3@1|root,32SH9@2|Bacteria,1N02U@1224|Proteobacteria,1SA77@1236|Gammaproteobacteria,1X22S@135613|Chromatiales	135613|Chromatiales	S	Protein of Unknown function (DUF2784)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2784
k59_209875_1	1499967.BAYZ01000068_gene1948	1.34e-87	273.0	COG2204@1|root,COG2204@2|Bacteria,2NNWS@2323|unclassified Bacteria	2|Bacteria	T	Two component, sigma54 specific, transcriptional regulator, Fis family	-	-	-	ko:K07714	ko02020,map02020	M00500	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
k59_4108_1	1121405.dsmv_1490	1.62e-71	237.0	COG0243@1|root,COG0243@2|Bacteria,1NR6J@1224|Proteobacteria,43BMM@68525|delta/epsilon subdivisions,2WJJV@28221|Deltaproteobacteria,2MHWI@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
k59_156801_1	1265505.ATUG01000002_gene1612	4.98e-94	292.0	COG2204@1|root,COG4191@1|root,COG2204@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42PZ5@68525|delta/epsilon subdivisions,2WKB1@28221|Deltaproteobacteria,2MIJB@213118|Desulfobacterales	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
k59_126545_1	1121405.dsmv_3781	5.28e-124	365.0	COG5421@1|root,COG5421@2|Bacteria,1R3NX@1224|Proteobacteria,42QDV@68525|delta/epsilon subdivisions,2WIRQ@28221|Deltaproteobacteria,2MN1S@213118|Desulfobacterales	68525|delta/epsilon subdivisions	L	PFAM transposase IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
k59_19827_1	1469607.KK073769_gene5573	2.26e-193	549.0	COG3385@1|root,COG3385@2|Bacteria,1G27F@1117|Cyanobacteria,1HM6Y@1161|Nostocales	1117|Cyanobacteria	L	PFAM Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
k59_111190_1	1499967.BAYZ01000013_gene6451	1.7e-192	548.0	COG0033@1|root,COG0033@2|Bacteria,2NS5G@2323|unclassified Bacteria	2|Bacteria	G	Phosphoglucomutase/phosphomannomutase, C-terminal domain	pgm	GO:0000271,GO:0003674,GO:0003824,GO:0004614,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0005996,GO:0006006,GO:0006012,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016052,GO:0016853,GO:0016866,GO:0016868,GO:0019318,GO:0019320,GO:0019388,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0055114,GO:0071704,GO:1901575,GO:1901576	5.4.2.2	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00549	R00959,R01057,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	iAPECO1_1312.APECO1_1376,iECED1_1282.ECED1_0670,iECNA114_1301.ECNA114_0627,iECOK1_1307.ECOK1_0699,iECP_1309.ECP_0709,iECS88_1305.ECS88_0725,iJN678.pgm,iLF82_1304.LF82_1632,iNRG857_1313.NRG857_03110,iUMN146_1321.UM146_14115,iYL1228.KPN_00711	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
k59_65255_1	269799.Gmet_2371	1.08e-28	125.0	COG1480@1|root,COG1480@2|Bacteria,1NCY5@1224|Proteobacteria,42MI9@68525|delta/epsilon subdivisions,2WJI1@28221|Deltaproteobacteria,43UC4@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Metal-dependent phosphohydrolase	-	-	-	ko:K07037	-	-	-	-	ko00000	-	-	-	7TM-7TMR_HD,7TMR-HDED,HD
k59_103628_1	335543.Sfum_0588	1.4e-88	273.0	COG2704@1|root,COG2704@2|Bacteria,1MVHH@1224|Proteobacteria,42MDH@68525|delta/epsilon subdivisions,2WU9Z@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane	-	-	-	ko:K07791	-	-	-	-	ko00000,ko02000	2.A.13.1	-	-	DcuA_DcuB
k59_232842_1	247490.KSU1_B0405	3.42e-70	217.0	COG1765@1|root,COG1765@2|Bacteria	2|Bacteria	O	OsmC-like protein	-	-	-	-	-	-	-	-	-	-	-	-	OsmC
k59_187312_1	316067.Geob_2641	3.58e-45	159.0	COG3005@1|root,COG3005@2|Bacteria	2|Bacteria	C	denitrification pathway	-	-	-	-	-	-	-	-	-	-	-	-	Paired_CXXCH_1
k59_27123_1	335543.Sfum_1278	1.67e-117	357.0	COG0427@1|root,COG0454@1|root,COG0427@2|Bacteria,COG0456@2|Bacteria,1MUGE@1224|Proteobacteria,42MHC@68525|delta/epsilon subdivisions,2WINZ@28221|Deltaproteobacteria,2MR2F@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	acetyl-CoA	-	-	-	ko:K18122,ko:K18288	ko00650,ko00660,ko01100,ko01200,map00650,map00660,map01100,map01200	-	R02407,R05336,R10600	RC00012,RC00014	ko00000,ko00001,ko01000	-	-	iAF987.Gmet_2142,iAF987.Gmet_3304	AcetylCoA_hyd_C,AcetylCoA_hydro,Acetyltransf_1,Acetyltransf_3
k59_12886_1	715451.ambt_18175	6.36e-48	172.0	COG0427@1|root,COG1247@1|root,COG0427@2|Bacteria,COG1247@2|Bacteria,1MUGE@1224|Proteobacteria,1RP19@1236|Gammaproteobacteria,46429@72275|Alteromonadaceae	1236|Gammaproteobacteria	C	acetyl-CoA hydrolase	-	-	-	ko:K18288	ko00660,map00660	-	R02407,R10600	RC00012,RC00014	ko00000,ko00001,ko01000	-	-	-	AcetylCoA_hyd_C,AcetylCoA_hydro,Acetyltransf_1,Acetyltransf_3
k59_187314_1	555088.DealDRAFT_2322	2.29e-82	264.0	COG0318@1|root,COG0318@2|Bacteria,1TPSX@1239|Firmicutes,248JC@186801|Clostridia,42KF5@68298|Syntrophomonadaceae	186801|Clostridia	IQ	PFAM AMP-dependent synthetase and ligase	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
k59_19848_1	1121405.dsmv_0585	5.2e-74	244.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,42M2R@68525|delta/epsilon subdivisions,2WJ4J@28221|Deltaproteobacteria,2MHN2@213118|Desulfobacterales	28221|Deltaproteobacteria	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
k59_163794_1	880073.Calab_1086	3.03e-61	201.0	COG2203@1|root,COG3437@1|root,COG2203@2|Bacteria,COG3437@2|Bacteria,2NQE8@2323|unclassified Bacteria	2|Bacteria	T	HD domain	-	-	-	ko:K07814	-	-	-	-	ko00000,ko02022	-	-	-	GAF,GAF_2,HD,HD_5
k59_239503_1	880072.Desac_2296	1.88e-57	200.0	COG1480@1|root,COG1480@2|Bacteria,1NCY5@1224|Proteobacteria,42MI9@68525|delta/epsilon subdivisions,2WJI1@28221|Deltaproteobacteria,2MR04@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	7TM-HD extracellular	-	-	-	ko:K07037	-	-	-	-	ko00000	-	-	-	7TM-7TMR_HD,7TMR-HDED,HD
k59_126591_2	1121413.JMKT01000010_gene868	1.24e-55	181.0	COG1738@1|root,COG1738@2|Bacteria,1RJV6@1224|Proteobacteria,43BF6@68525|delta/epsilon subdivisions,2X6TJ@28221|Deltaproteobacteria,2MH6P@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage	-	-	-	ko:K09125	-	-	-	-	ko00000	-	-	-	Vut_1
k59_134071_1	1168034.FH5T_05330	1.73e-57	192.0	COG0739@1|root,COG0739@2|Bacteria,4NECF@976|Bacteroidetes,2FQ2Q@200643|Bacteroidia	976|Bacteroidetes	M	Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
k59_103644_1	589924.Ferp_0086	7.56e-86	272.0	COG0574@1|root,arCOG01114@2157|Archaea,2XVIT@28890|Euryarchaeota	28890|Euryarchaeota	G	PEP-utilising enzyme, mobile domain	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers
k59_111225_1	1121405.dsmv_1295	3.26e-130	375.0	COG1013@1|root,COG1013@2|Bacteria,1R5BF@1224|Proteobacteria,42MD3@68525|delta/epsilon subdivisions,2WJQ0@28221|Deltaproteobacteria,2MIEW@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM Thiamine pyrophosphate	-	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
k59_163811_1	472759.Nhal_0308	6.91e-64	206.0	COG1398@1|root,COG1398@2|Bacteria,1N2MA@1224|Proteobacteria,1RM88@1236|Gammaproteobacteria,1X29C@135613|Chromatiales	135613|Chromatiales	I	Fatty acid desaturase	-	-	1.14.19.1	ko:K00507	ko01040,ko01212,ko03320,ko04152,ko04212,map01040,map01212,map03320,map04152,map04212	-	R02222	RC00917	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase
k59_209929_1	138119.DSY4729	2.81e-54	189.0	COG0247@1|root,COG0247@2|Bacteria,1TPG1@1239|Firmicutes,24BBE@186801|Clostridia,260K6@186807|Peptococcaceae	186801|Clostridia	C	Fe-S oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_8,Nitrate_red_gam
k59_42378_1	582899.Hden_0708	3.53e-36	132.0	COG3293@1|root,COG3293@2|Bacteria,1PVIT@1224|Proteobacteria,2TURP@28211|Alphaproteobacteria,3N8G4@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DUF4096
k59_42378_2	1521187.JPIM01000127_gene250	3.93e-06	47.0	COG3293@1|root,COG3293@2|Bacteria	2|Bacteria	L	Transposase	-	-	-	ko:K07492	-	-	-	-	ko00000	-	-	-	DDE_Tnp_1,DDE_Tnp_1_2,DUF4096
k59_88202_1	570952.ATVH01000011_gene353	8.45e-29	119.0	2EXSU@1|root,33R23@2|Bacteria,1NS77@1224|Proteobacteria,2UR4M@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_95984_1	1459636.NTE_01195	7.28e-08	52.0	COG1522@1|root,arCOG01117@2157|Archaea	1459636.NTE_01195|-	K	COG1522 Transcriptional regulators	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_239510_1	1121405.dsmv_1522	2.89e-69	222.0	COG2271@1|root,COG2271@2|Bacteria,1PND6@1224|Proteobacteria,42QTW@68525|delta/epsilon subdivisions,2WMNU@28221|Deltaproteobacteria,2MJYF@213118|Desulfobacterales	28221|Deltaproteobacteria	G	Major Facilitator Superfamily	-	-	-	ko:K02445	-	-	-	-	ko00000,ko02000	2.A.1.4.3	-	-	MFS_1
k59_92196_1	717231.Flexsi_0440	4.12e-55	184.0	COG3547@1|root,COG3547@2|Bacteria	2|Bacteria	L	Transposase (IS116 IS110 IS902 family)	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_92198_1	1242864.D187_004810	5.12e-76	238.0	COG0202@1|root,COG0202@2|Bacteria,1MU75@1224|Proteobacteria,42MIX@68525|delta/epsilon subdivisions,2WJ5K@28221|Deltaproteobacteria,2YXN1@29|Myxococcales	28221|Deltaproteobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
k59_31553_1	644282.Deba_1092	7.28e-10	57.8	COG1838@1|root,COG1838@2|Bacteria,1RCSV@1224|Proteobacteria,42NRW@68525|delta/epsilon subdivisions,2X5RX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Hydro-lyase, Fe-S type, tartrate fumarate subfamily, beta subunit	-	-	4.2.1.2	ko:K01678	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumerase_C
k59_31553_2	1121448.DGI_1571	4.4e-54	177.0	COG1951@1|root,COG1951@2|Bacteria,1MUV9@1224|Proteobacteria,42MC7@68525|delta/epsilon subdivisions,2WKIV@28221|Deltaproteobacteria,2M85S@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	hydro-lyase, Fe-S type, tartrate fumarate subfamily, alpha subunit	fumA	-	4.2.1.2	ko:K01677	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumerase
k59_183202_1	1123508.JH636441_gene3358	3.98e-51	184.0	COG0046@1|root,COG0046@2|Bacteria,2IXRT@203682|Planctomycetes	203682|Planctomycetes	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C,PurS
k59_16300_1	1167006.UWK_00151	1.41e-101	329.0	COG0500@1|root,COG4258@1|root,COG0500@2|Bacteria,COG4258@2|Bacteria,1MU1E@1224|Proteobacteria,42P70@68525|delta/epsilon subdivisions,2WJGD@28221|Deltaproteobacteria,2MJYG@213118|Desulfobacterales	28221|Deltaproteobacteria	Q	MMPL family	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
k59_92203_1	1121405.dsmv_2816	1.33e-58	198.0	COG1482@1|root,COG1482@2|Bacteria,1MUD8@1224|Proteobacteria,42QR1@68525|delta/epsilon subdivisions,2WU24@28221|Deltaproteobacteria,2MMJP@213118|Desulfobacterales	28221|Deltaproteobacteria	G	Phosphomannose isomerase type I	-	-	5.3.1.8,5.4.2.8	ko:K01809,ko:K01840	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01818,R01819	RC00376,RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PMI_typeI
k59_175670_1	742723.HMPREF9477_00970	5.2e-65	215.0	COG0129@1|root,COG0129@2|Bacteria,1TP1R@1239|Firmicutes,247UC@186801|Clostridia,27I6F@186928|unclassified Lachnospiraceae	186801|Clostridia	EG	Dehydratase family	-	-	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
k59_198333_1	1121403.AUCV01000020_gene3080	3.25e-07	56.6	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02457,ko:K02459,ko:K10927,ko:K12285	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,SBP_bac_10
k59_99835_1	933262.AXAM01000052_gene1988	1.87e-111	329.0	COG0050@1|root,COG0050@2|Bacteria,1MVC0@1224|Proteobacteria,42MWZ@68525|delta/epsilon subdivisions,2WJ2B@28221|Deltaproteobacteria,2MHTQ@213118|Desulfobacterales	28221|Deltaproteobacteria	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
k59_92205_1	933262.AXAM01000027_gene2112	4.11e-66	217.0	COG2885@1|root,COG3267@1|root,COG2885@2|Bacteria,COG3267@2|Bacteria,1MU3G@1224|Proteobacteria,42PJ3@68525|delta/epsilon subdivisions,2WJF6@28221|Deltaproteobacteria,2MJ4S@213118|Desulfobacterales	28221|Deltaproteobacteria	MU	AAA domain	-	-	-	ko:K02450	-	M00331	-	-	ko00000,ko00002,ko02044	9.B.42	-	-	AAA_22,OmpA
k59_167920_1	234267.Acid_6259	4.82e-131	392.0	COG1321@1|root,COG1321@2|Bacteria	2|Bacteria	K	iron dependent repressor	nagC	-	-	ko:K02003,ko:K02565,ko:K15545	-	M00258	-	-	ko00000,ko00002,ko02000,ko03000	3.A.1	-	-	HTH_IclR,MarR,ROK
k59_160619_1	56780.SYN_00833	1.65e-58	199.0	COG1305@1|root,COG1305@2|Bacteria,1Q1D3@1224|Proteobacteria,43772@68525|delta/epsilon subdivisions,2WSIA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Transglutaminase/protease-like homologues	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
k59_137784_1	370438.PTH_2126	6e-32	122.0	COG0517@1|root,COG0517@2|Bacteria,1V0XU@1239|Firmicutes,24I2P@186801|Clostridia,261WS@186807|Peptococcaceae	186801|Clostridia	S	PFAM CBS domain	acuB	-	-	ko:K04767	-	-	-	-	ko00000	-	-	-	ACT,CBS
k59_1201_1	556261.HMPREF0240_00631	4.91e-70	232.0	COG0493@1|root,COG3383@1|root,COG0493@2|Bacteria,COG3383@2|Bacteria,1TQ1A@1239|Firmicutes,248EK@186801|Clostridia,36FQY@31979|Clostridiaceae	186801|Clostridia	C	Oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer2_4,Fer4,Fer4_20,Fer4_7,NADH-G_4Fe-4S_3,Pyr_redox_2
k59_160632_1	1121085.AUCI01000006_gene1479	1.05e-13	72.4	COG1494@1|root,COG1494@2|Bacteria,1TP0D@1239|Firmicutes,4H9MV@91061|Bacilli,1ZD19@1386|Bacillus	91061|Bacilli	G	fructose-1,6-bisphosphatase	glpX	-	3.1.3.11	ko:K02446	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00165,M00167	R00762,R04780	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FBPase_glpX
k59_160632_2	335543.Sfum_1296	5.26e-11	58.5	COG1532@1|root,COG1532@2|Bacteria,1NHW7@1224|Proteobacteria,42X58@68525|delta/epsilon subdivisions,2WSZ3@28221|Deltaproteobacteria,2MSBQ@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Predicted RNA-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	RNA_bind_2
k59_31568_1	1156935.QWE_07231	5.89e-36	138.0	COG0404@1|root,COG0665@1|root,COG0404@2|Bacteria,COG0665@2|Bacteria,1MUXJ@1224|Proteobacteria,2TRGS@28211|Alphaproteobacteria,4B8TC@82115|Rhizobiaceae	28211|Alphaproteobacteria	E	Belongs to the GcvT family	-	-	1.5.3.19	ko:K19191	ko00760,ko01120,map00760,map01120	-	R10102	RC00060,RC00557	ko00000,ko00001,ko01000	-	-	-	DAO,FAO_M,GCV_T,GCV_T_C
k59_8833_1	1265505.ATUG01000003_gene146	3.63e-58	187.0	COG1024@1|root,COG1024@2|Bacteria,1R61Y@1224|Proteobacteria,42P4M@68525|delta/epsilon subdivisions,2WJJU@28221|Deltaproteobacteria,2MIKD@213118|Desulfobacterales	28221|Deltaproteobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	4.2.1.17	ko:K01715	ko00650,ko01200,map00650,map01200	-	R03026	RC00831	ko00000,ko00001,ko01000	-	-	-	ECH_1
k59_8833_2	335543.Sfum_0940	1.5e-24	96.7	COG2062@1|root,COG2062@2|Bacteria,1RGWQ@1224|Proteobacteria,42SEE@68525|delta/epsilon subdivisions,2WPM2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	PFAM Phosphoglycerate mutase	-	-	-	ko:K08296	-	-	-	-	ko00000,ko01000	-	-	-	His_Phos_1
k59_221284_1	1121405.dsmv_2842	1.05e-112	332.0	COG1893@1|root,COG1893@2|Bacteria,1PHGH@1224|Proteobacteria,43A7I@68525|delta/epsilon subdivisions,2X25K@28221|Deltaproteobacteria,2MNME@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Ketopantoate reductase PanE/ApbA C terminal	-	-	1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000	-	-	-	ApbA,ApbA_C
k59_62073_1	1304885.AUEY01000008_gene2052	1.19e-131	385.0	COG0538@1|root,COG0538@2|Bacteria,1MW3J@1224|Proteobacteria,42M56@68525|delta/epsilon subdivisions,2WJ8W@28221|Deltaproteobacteria,2MI0G@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Isocitrate dehydrogenase	icd	-	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
k59_31570_1	1121405.dsmv_1454	2.84e-85	276.0	COG2937@1|root,COG2937@2|Bacteria,1MWZ6@1224|Proteobacteria,42MN4@68525|delta/epsilon subdivisions,2WJJ5@28221|Deltaproteobacteria,2MHRG@213118|Desulfobacterales	28221|Deltaproteobacteria	I	Belongs to the GPAT DAPAT family	plsB	-	2.3.1.15	ko:K00631	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
k59_145326_1	1267533.KB906734_gene3895	1.39e-09	64.7	COG1721@1|root,COG1721@2|Bacteria	2|Bacteria	E	protein (some members contain a von Willebrand factor type A (vWA) domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,DUF58
k59_145326_2	953739.SVEN_2760	3.87e-55	184.0	COG0714@1|root,COG0714@2|Bacteria,2GK07@201174|Actinobacteria	201174|Actinobacteria	S	associated with various cellular activities	moxR2	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
k59_183226_1	880072.Desac_1631	1.15e-59	203.0	COG0303@1|root,COG1910@1|root,COG0303@2|Bacteria,COG1910@2|Bacteria,1MVD5@1224|Proteobacteria,42NQY@68525|delta/epsilon subdivisions,2WISG@28221|Deltaproteobacteria,2MQ4V@213462|Syntrophobacterales	28221|Deltaproteobacteria	HP	TIGRFAM molybdenum cofactor synthesis domain	-	-	2.10.1.1	ko:K03750,ko:K07219	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N,PBP_like
k59_228702_1	747365.Thena_0747	1.72e-06	55.1	COG0617@1|root,COG0617@2|Bacteria,1TQ2A@1239|Firmicutes,247XC@186801|Clostridia,42FBY@68295|Thermoanaerobacterales	186801|Clostridia	H	PFAM Polynucleotide adenylyltransferase region	-	-	2.7.7.19,2.7.7.72	ko:K00970,ko:K00974	ko03013,ko03018,map03013,map03018	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	HD,PolyA_pol,PolyA_pol_RNAbd,tRNA_NucTran2_2
k59_99862_1	335543.Sfum_3028	6.58e-48	164.0	COG1183@1|root,COG1183@2|Bacteria,1MWD9@1224|Proteobacteria,42QV4@68525|delta/epsilon subdivisions,2WMR6@28221|Deltaproteobacteria,2MQE6@213462|Syntrophobacterales	28221|Deltaproteobacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pssA	-	2.7.8.8	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	M00093	R01800	RC00002,RC00017,RC02795	ko00000,ko00001,ko00002,ko01000	-	-	-	CDP-OH_P_transf
k59_183227_2	933262.AXAM01000042_gene1832	1.38e-63	206.0	COG3825@1|root,COG3825@2|Bacteria,1MUAJ@1224|Proteobacteria,42N7R@68525|delta/epsilon subdivisions,2WJBI@28221|Deltaproteobacteria,2MIB1@213118|Desulfobacterales	28221|Deltaproteobacteria	S	VWA containing CoxE family protein	-	-	-	ko:K09989	-	-	-	-	ko00000	-	-	-	VWA_CoxE
k59_39241_1	565045.NOR51B_1830	3.59e-70	223.0	COG0774@1|root,COG0774@2|Bacteria,1MV6T@1224|Proteobacteria,1RQ72@1236|Gammaproteobacteria,1J54C@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis	lpxC	GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0008610,GO:0008654,GO:0008759,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016787,GO:0016810,GO:0016811,GO:0019213,GO:0019637,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044464,GO:0046467,GO:0046493,GO:0046872,GO:0046914,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	3.5.1.108	ko:K02535	ko00540,ko01100,map00540,map01100	M00060	R04587	RC00166,RC00300	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	iECS88_1305.ECS88_0100	LpxC
k59_122616_1	314345.SPV1_04173	1.86e-38	134.0	COG0071@1|root,COG0071@2|Bacteria,1N7C7@1224|Proteobacteria	1224|Proteobacteria	O	Belongs to the small heat shock protein (HSP20) family	hspA-1	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
k59_221296_1	1379698.RBG1_1C00001G1620	1.99e-32	127.0	COG2222@1|root,COG2222@2|Bacteria,2NQVV@2323|unclassified Bacteria	2|Bacteria	M	Bacterial phospho-glucose isomerase C-terminal SIS domain	pgi	-	5.3.1.8,5.3.1.9	ko:K15916	ko00010,ko00030,ko00051,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R01819,R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000	-	-	-	SIS,bact-PGI_C
k59_1217_1	404589.Anae109_2754	1.32e-75	240.0	COG1148@1|root,COG1148@2|Bacteria,1PTJ7@1224|Proteobacteria,42NJN@68525|delta/epsilon subdivisions,2WJHG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_6
k59_46779_1	28072.Nos7524_1286	1.38e-07	58.5	COG2931@1|root,COG3210@1|root,COG3291@1|root,COG3595@1|root,COG4070@1|root,COG2931@2|Bacteria,COG3210@2|Bacteria,COG3291@2|Bacteria,COG3595@2|Bacteria,COG4070@2|Bacteria,1GHDQ@1117|Cyanobacteria,1HUA0@1161|Nostocales	1117|Cyanobacteria	Q	Domain of unknown function (DUF4114)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4114
k59_99871_1	1121405.dsmv_3059	2.6e-69	230.0	COG0751@1|root,COG0751@2|Bacteria,1MV2F@1224|Proteobacteria,42M6A@68525|delta/epsilon subdivisions,2WJIT@28221|Deltaproteobacteria,2MHVB@213118|Desulfobacterales	28221|Deltaproteobacteria	J	glycyl-tRNA synthetase, beta	glyS	-	6.1.1.14	ko:K01879	ko00970,map00970	M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_1,tRNA_synt_2f
k59_24066_1	709032.Sulku_2664	1.9e-19	93.6	COG1538@1|root,COG1538@2|Bacteria,1MYXE@1224|Proteobacteria,42TA7@68525|delta/epsilon subdivisions,2YS8S@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
k59_84609_1	926561.KB900622_gene462	1.29e-34	130.0	COG4974@1|root,COG4974@2|Bacteria,1TR57@1239|Firmicutes,24ACW@186801|Clostridia,3WB6M@53433|Halanaerobiales	186801|Clostridia	L	Phage integrase, N-terminal SAM-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
k59_84609_2	1121396.KB892913_gene116	3.56e-70	229.0	COG0517@1|root,COG0517@2|Bacteria,1MXI6@1224|Proteobacteria,42WI2@68525|delta/epsilon subdivisions,2WRPD@28221|Deltaproteobacteria,2MQ18@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Transposase zinc-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Y2_Tnp,Zn_Tnp_IS91
k59_24067_1	545693.BMQ_3328	6.36e-51	171.0	COG0604@1|root,COG0604@2|Bacteria,1TSWF@1239|Firmicutes,4HANV@91061|Bacilli,1ZPZP@1386|Bacillus	91061|Bacilli	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N,ADH_zinc_N_2
k59_190705_1	933262.AXAM01000052_gene2002	1.14e-96	284.0	COG0094@1|root,COG0094@2|Bacteria,1MUU9@1224|Proteobacteria,42QS6@68525|delta/epsilon subdivisions,2WMPD@28221|Deltaproteobacteria,2MJFM@213118|Desulfobacterales	28221|Deltaproteobacteria	J	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits	rplE	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02931	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L5,Ribosomal_L5_C
k59_54350_1	641107.CDLVIII_4284	6.44e-46	155.0	COG1853@1|root,COG1853@2|Bacteria,1TSTQ@1239|Firmicutes,24FYK@186801|Clostridia,36EHC@31979|Clostridiaceae	186801|Clostridia	S	Flavin reductase like domain	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
k59_213528_1	1121405.dsmv_0929	1.55e-63	213.0	COG0457@1|root,COG0501@1|root,COG0457@2|Bacteria,COG0501@2|Bacteria,1R5A7@1224|Proteobacteria,42MP6@68525|delta/epsilon subdivisions,2WK92@28221|Deltaproteobacteria,2MIHI@213118|Desulfobacterales	28221|Deltaproteobacteria	O	PFAM peptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48,TPR_11,TPR_17
k59_221305_1	1267534.KB906757_gene860	1.87e-36	139.0	COG1519@1|root,COG1519@2|Bacteria,3Y3X5@57723|Acidobacteria,2JI61@204432|Acidobacteriia	204432|Acidobacteriia	M	3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase)	-	-	2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15	ko:K02527	ko00540,ko01100,map00540,map01100	M00060,M00080	R04658,R05074,R09763	RC00009,RC00077,RC00247	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT30	-	Glycos_transf_N
k59_24075_1	908340.HMPREF9406_0142	4.89e-14	67.0	COG3311@1|root,COG3311@2|Bacteria,1VFSN@1239|Firmicutes,24S51@186801|Clostridia,36PPB@31979|Clostridiaceae	186801|Clostridia	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
k59_228727_1	671143.DAMO_0837	2.31e-23	97.4	COG1277@1|root,COG1277@2|Bacteria,2NPGK@2323|unclassified Bacteria	2|Bacteria	S	ABC-2 family transporter protein	yxlG	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC2_membrane_3,ABC_transp_aux
k59_228727_2	880072.Desac_0030	1.01e-15	77.4	COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,42NF6@68525|delta/epsilon subdivisions,2WKVH@28221|Deltaproteobacteria,2MR9V@213462|Syntrophobacterales	28221|Deltaproteobacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
k59_228728_1	316067.Geob_2279	4.82e-61	196.0	COG1137@1|root,COG1137@2|Bacteria,1MU8M@1224|Proteobacteria,42M4J@68525|delta/epsilon subdivisions,2WJM8@28221|Deltaproteobacteria,43T7P@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	PFAM ABC transporter related	lptB	-	-	ko:K06861	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	1.B.42.1	-	-	ABC_tran,BCA_ABC_TP_C
k59_190716_1	713587.THITH_09665	3.58e-61	199.0	2CAM1@1|root,301FE@2|Bacteria,1RJ36@1224|Proteobacteria,1S7TX@1236|Gammaproteobacteria,1X0ZI@135613|Chromatiales	135613|Chromatiales	S	Ceramidase	-	-	-	-	-	-	-	-	-	-	-	-	Ceramidase
k59_153062_2	4006.Lus10031083	0.000281	45.8	2CY0S@1|root,2S16E@2759|Eukaryota,37VTN@33090|Viridiplantae,3GJDN@35493|Streptophyta,4JPQ5@91835|fabids	35493|Streptophyta	S	FHA domain-containing protein	-	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044464,GO:0097159,GO:1901363	-	-	-	-	-	-	-	-	-	-	FHA
k59_213543_1	575605.ACQN01000020_gene713	6.06e-05	50.8	COG1737@1|root,COG1737@2|Bacteria,1TR5E@1239|Firmicutes,4HGM0@91061|Bacilli,3F49F@33958|Lactobacillaceae	91061|Bacilli	K	Helix-turn-helix domain, rpiR family	-	-	-	-	-	-	-	-	-	-	-	iSB619.SA_RS01765	HTH_6,SIS
k59_198387_1	1535422.ND16A_0193	0.000432	48.1	COG4967@1|root,COG4967@2|Bacteria,1NJIG@1224|Proteobacteria,1T19T@1236|Gammaproteobacteria	1236|Gammaproteobacteria	NU	type IV pilus modification protein PilV	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
k59_175709_1	1121451.DESAM_22429	2.05e-40	149.0	COG4671@1|root,COG4671@2|Bacteria,1NS2U@1224|Proteobacteria,42YUZ@68525|delta/epsilon subdivisions,2WTMQ@28221|Deltaproteobacteria,2M9WI@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Glycosyl Transferase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1239_1	1123037.AUDE01000046_gene849	1.15e-107	327.0	COG1228@1|root,COG1228@2|Bacteria,4NFI3@976|Bacteroidetes,1HY2V@117743|Flavobacteriia	976|Bacteroidetes	Q	Imidazolonepropionase and related	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
k59_39257_1	243231.GSU2321	3.13e-14	70.5	2E7HP@1|root,33206@2|Bacteria,1NN68@1224|Proteobacteria	1224|Proteobacteria	S	Protein of unknown function (DUF1475)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1475
k59_39257_2	1499967.BAYZ01000048_gene2696	2.57e-59	195.0	COG2230@1|root,COG2230@2|Bacteria	2|Bacteria	M	cyclopropane-fatty-acyl-phospholipid synthase	cfa	-	2.1.1.317,2.1.1.79	ko:K00574,ko:K20238	-	-	-	-	ko00000,ko01000	-	-	iJN746.PP_2734	CMAS
k59_160657_1	1121921.KB898706_gene3039	7.36e-52	179.0	COG1783@1|root,COG1783@2|Bacteria,1R66A@1224|Proteobacteria,1RQFD@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Phage terminase, large subunit	Z012_12305	-	-	ko:K06909	-	-	-	-	ko00000	-	-	-	Terminase_3,Terminase_3C
k59_137850_1	933262.AXAM01000077_gene1703	1.11e-83	261.0	COG0569@1|root,COG0569@2|Bacteria,1MW8R@1224|Proteobacteria,42NWZ@68525|delta/epsilon subdivisions,2WJU7@28221|Deltaproteobacteria,2MJ2C@213118|Desulfobacterales	28221|Deltaproteobacteria	P	PFAM TrkA-N domain	trkA	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
k59_16364_1	290315.Clim_1455	3.23e-55	184.0	COG1509@1|root,COG1509@2|Bacteria	2|Bacteria	E	lysine 2,3-aminomutase activity	-	-	5.4.3.2	ko:K01843	ko00310,map00310	-	R00461	RC00303	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Fer4_14,Radical_SAM
k59_183249_1	485916.Dtox_2613	9.39e-90	297.0	COG1201@1|root,COG1201@2|Bacteria,1UHYQ@1239|Firmicutes,25E79@186801|Clostridia	186801|Clostridia	L	DEAD DEAH box helicase	-	-	-	ko:K03724	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DEAD_assoc,Helicase_C
k59_183250_1	439235.Dalk_2752	1.85e-44	160.0	COG0021@1|root,COG0021@2|Bacteria,1MUEY@1224|Proteobacteria,42M80@68525|delta/epsilon subdivisions,2WINJ@28221|Deltaproteobacteria,2MHY9@213118|Desulfobacterales	28221|Deltaproteobacteria	G	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate	tkt	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
k59_122667_1	439235.Dalk_1918	2.43e-49	160.0	COG0049@1|root,COG0049@2|Bacteria,1MXC8@1224|Proteobacteria,42QR7@68525|delta/epsilon subdivisions,2WNFM@28221|Deltaproteobacteria,2MJJG@213118|Desulfobacterales	28221|Deltaproteobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA	rpsG	GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02992	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S7
k59_16380_1	118005.AWNK01000006_gene1381	5.63e-53	182.0	COG0306@1|root,COG0306@2|Bacteria	2|Bacteria	P	phosphate transporter	pitA	GO:0003674,GO:0005215,GO:0005315,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0015291,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0035435,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661	-	ko:K03306	-	-	-	-	ko00000	2.A.20	-	-	PHO4
k59_31590_1	1307759.JOMJ01000003_gene257	6.76e-28	114.0	COG0068@1|root,COG0068@2|Bacteria,1MVP8@1224|Proteobacteria,42M3G@68525|delta/epsilon subdivisions,2WJ51@28221|Deltaproteobacteria,2M8IT@213115|Desulfovibrionales	28221|Deltaproteobacteria	O	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide	hypF	-	-	ko:K04656	-	-	-	-	ko00000	-	-	iAF987.Gmet_0119	Acylphosphatase,Sua5_yciO_yrdC,zf-HYPF
k59_138307_1	903818.KI912268_gene620	6.24e-83	271.0	COG0243@1|root,COG0243@2|Bacteria,3Y2IU@57723|Acidobacteria	2|Bacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	athL	-	1.7.2.3	ko:K07812	-	-	-	-	ko00000,ko01000,ko02000	5.A.3.4	-	-	Molybdopterin,Molydop_binding
k59_39698_1	56780.SYN_01534	8.29e-25	108.0	COG2239@1|root,COG2239@2|Bacteria,1MW24@1224|Proteobacteria,42MA7@68525|delta/epsilon subdivisions,2WIPC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Acts as a magnesium transporter	mgtE	-	-	ko:K06213	-	-	-	-	ko00000,ko02000	1.A.26.1	-	-	CBS,MgtE,MgtE_N
k59_145793_1	1121434.AULY01000013_gene63	4e-54	179.0	COG1023@1|root,COG1023@2|Bacteria,1QU14@1224|Proteobacteria,42MJI@68525|delta/epsilon subdivisions,2WJQP@28221|Deltaproteobacteria,2M88E@213115|Desulfovibrionales	28221|Deltaproteobacteria	G	PFAM 6-phosphogluconate dehydrogenase NAD-binding	gnd	-	1.1.1.343,1.1.1.44	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	M00004,M00006	R01528,R10221	RC00001,RC00539	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2620	6PGD,NAD_binding_2
k59_198906_1	497964.CfE428DRAFT_6230	3e-08	59.3	COG0784@1|root,COG2204@1|root,COG4191@1|root,COG0784@2|Bacteria,COG2204@2|Bacteria,COG4191@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	ko:K01991,ko:K03413	ko02020,ko02026,ko02030,map02020,map02026,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02000,ko02022,ko02035	1.B.18	-	-	GAF_2,HATPase_c,HisKA,PAS_9,Response_reg
k59_42933_1	1265505.ATUG01000002_gene2174	4.22e-86	271.0	COG4231@1|root,COG4231@2|Bacteria,1MUKS@1224|Proteobacteria,42N44@68525|delta/epsilon subdivisions,2WKYE@28221|Deltaproteobacteria,2MHUM@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates	iorA-2	-	1.2.7.8	ko:K00179	-	-	-	-	br01601,ko00000,ko01000	-	-	-	Fer4,POR_N,TPP_enzyme_C
k59_240136_1	1089550.ATTH01000001_gene153	2.11e-81	266.0	COG1615@1|root,COG1615@2|Bacteria,4P0RW@976|Bacteroidetes,1FJVZ@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Uncharacterised protein family (UPF0182)	-	-	-	ko:K09118	-	-	-	-	ko00000	-	-	-	UPF0182
k59_188027_2	1121405.dsmv_1725	6.33e-59	192.0	COG0484@1|root,COG0484@2|Bacteria,1MVMS@1224|Proteobacteria,42KZM@68525|delta/epsilon subdivisions,2WJGP@28221|Deltaproteobacteria,2MIAD@213118|Desulfobacterales	28221|Deltaproteobacteria	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
k59_127106_1	98439.AJLL01000089_gene3723	5.82e-44	149.0	COG0529@1|root,COG0529@2|Bacteria	2|Bacteria	P	adenylylsulfate kinase activity	cysC	GO:0000096,GO:0000103,GO:0003674,GO:0003824,GO:0004020,GO:0004779,GO:0004781,GO:0006082,GO:0006520,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010134,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016779,GO:0019379,GO:0019419,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0055114,GO:0070566,GO:0071704,GO:1901564	1.8.4.10,1.8.4.8,2.7.1.25,2.7.7.4	ko:K00390,ko:K00860,ko:K00958,ko:K13811	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00509,R00529,R02021,R04928,R04929	RC00002,RC00007,RC00078,RC02809,RC02862,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase,ATP-sulfurylase,PUA_2
k59_96593_1	338966.Ppro_1404	8.36e-169	489.0	COG0443@1|root,COG0443@2|Bacteria,1MVEN@1224|Proteobacteria,42M64@68525|delta/epsilon subdivisions,2WIWS@28221|Deltaproteobacteria,43TCM@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
k59_202896_1	1265505.ATUG01000002_gene2074	7.57e-89	283.0	COG1109@1|root,COG1109@2|Bacteria,1QUGD@1224|Proteobacteria,43BUU@68525|delta/epsilon subdivisions,2WKYP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	phosphoglucomutase phosphomannomutase alpha beta alpha domain I	-	-	5.4.2.2,5.4.2.8	ko:K01835,ko:K01840	ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00114,M00549	R00959,R01057,R01818,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
k59_142321_1	933262.AXAM01000023_gene644	9.82e-93	295.0	COG0466@1|root,COG0466@2|Bacteria,1MUV2@1224|Proteobacteria,42M9W@68525|delta/epsilon subdivisions,2WJ29@28221|Deltaproteobacteria,2MJ5T@213118|Desulfobacterales	28221|Deltaproteobacteria	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon-2	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
k59_217713_1	706587.Desti_1653	7.37e-71	232.0	COG4191@1|root,COG4191@2|Bacteria,1MY5P@1224|Proteobacteria,42MTA@68525|delta/epsilon subdivisions,2WJ9Q@28221|Deltaproteobacteria,2MR6C@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	4HB_MCP_1,CHASE3,HAMP,HATPase_c,HisKA
k59_134790_1	595460.RRSWK_03709	3.04e-82	267.0	COG0457@1|root,COG1807@1|root,COG0457@2|Bacteria,COG1807@2|Bacteria,2IYMF@203682|Planctomycetes	203682|Planctomycetes	M	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_2,TPR_8
k59_210596_1	335543.Sfum_2005	3.36e-166	479.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,42NB6@68525|delta/epsilon subdivisions,2WIWE@28221|Deltaproteobacteria,2MQB7@213462|Syntrophobacterales	28221|Deltaproteobacteria	O	Belongs to the peptidase S1C family	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
k59_194548_1	933262.AXAM01000073_gene3363	6.08e-40	137.0	COG0558@1|root,COG0558@2|Bacteria,1RCZ7@1224|Proteobacteria,42QQ4@68525|delta/epsilon subdivisions,2WQGH@28221|Deltaproteobacteria,2MJJ6@213118|Desulfobacterales	28221|Deltaproteobacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pgsA	-	2.7.8.5	ko:K00995	ko00564,ko01100,map00564,map01100	-	R01801	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
k59_50691_1	177437.HRM2_35300	1.19e-30	127.0	COG1055@1|root,COG1055@2|Bacteria,1MUH8@1224|Proteobacteria,42KZP@68525|delta/epsilon subdivisions,2WKSV@28221|Deltaproteobacteria,2MHUQ@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Na H antiporter	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS,PAS
k59_65825_1	335543.Sfum_0664	1.22e-28	120.0	COG0309@1|root,COG0826@1|root,COG0309@2|Bacteria,COG0826@2|Bacteria,1MUQG@1224|Proteobacteria,42M8P@68525|delta/epsilon subdivisions,2X5K8@28221|Deltaproteobacteria,2MQGN@213462|Syntrophobacterales	28221|Deltaproteobacteria	O	PFAM peptidase U32	-	-	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_U32
k59_179424_1	96561.Dole_0660	6.47e-65	213.0	COG3039@1|root,COG3039@2|Bacteria,1QQ9Q@1224|Proteobacteria,42S7X@68525|delta/epsilon subdivisions,2WNJ2@28221|Deltaproteobacteria,2MJG4@213118|Desulfobacterales	28221|Deltaproteobacteria	L	PFAM transposase IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DUF772
k59_202908_1	338966.Ppro_1768	8.33e-65	205.0	COG0558@1|root,COG0558@2|Bacteria,1RCZ7@1224|Proteobacteria,42QQ4@68525|delta/epsilon subdivisions,2WQGH@28221|Deltaproteobacteria,43UAM@69541|Desulfuromonadales	28221|Deltaproteobacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pgsA	-	2.7.8.5	ko:K00995	ko00564,ko01100,map00564,map01100	-	R01801	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
k59_13601_1	455436.DS989811_gene1802	3.32e-08	60.5	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,1RMBS@1236|Gammaproteobacteria,465TY@72275|Alteromonadaceae	1236|Gammaproteobacteria	NTU	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB	-	-	-	-	-	-	-	-	-	-	-	-	GAF,T2SSE,T2SSE_N
k59_118812_1	1121456.ATVA01000011_gene1766	1.8e-55	196.0	COG1578@1|root,COG1578@2|Bacteria,1R50K@1224|Proteobacteria,42Q0S@68525|delta/epsilon subdivisions,2WJ5M@28221|Deltaproteobacteria,2M85H@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Protein of unknown function DUF89	-	-	-	-	-	-	-	-	-	-	-	-	DUF89
k59_65828_1	477641.MODMU_0029	1.16e-09	63.5	COG1716@1|root,COG1716@2|Bacteria,2GNU2@201174|Actinobacteria,4ESRE@85013|Frankiales	201174|Actinobacteria	T	FHA domain containing protein	fhaA	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944,GO:0097159,GO:1901363	-	-	-	-	-	-	-	-	-	-	DUF3662,FHA,Yop-YscD_cpl
k59_142347_1	439235.Dalk_1046	2.63e-71	237.0	COG1132@1|root,COG1132@2|Bacteria,1MWTY@1224|Proteobacteria,42N23@68525|delta/epsilon subdivisions,2WKW2@28221|Deltaproteobacteria,2MHZB@213118|Desulfobacterales	28221|Deltaproteobacteria	V	ABC transporter transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	ABC_membrane,ABC_tran
k59_172384_1	1121405.dsmv_0458	9.9e-53	186.0	COG1450@1|root,COG1450@2|Bacteria,1MUUA@1224|Proteobacteria,42M9I@68525|delta/epsilon subdivisions,2WK1H@28221|Deltaproteobacteria,2MIEH@213118|Desulfobacterales	28221|Deltaproteobacteria	NU	type II and III secretion system protein	gspD	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	Secretin,Secretin_N
k59_13605_1	909663.KI867150_gene677	9.41e-97	293.0	COG2309@1|root,COG2309@2|Bacteria,1MW2Y@1224|Proteobacteria,42P6P@68525|delta/epsilon subdivisions,2WJF8@28221|Deltaproteobacteria,2MQZ9@213462|Syntrophobacterales	28221|Deltaproteobacteria	E	Thermophilic metalloprotease (M29)	-	-	-	ko:K19689	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M29
k59_202912_1	667014.Thein_2037	1.73e-46	156.0	2EAAE@1|root,334ER@2|Bacteria,2GHMY@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_202912_2	273068.TTE0874	1.55e-39	149.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1TPKJ@1239|Firmicutes,248NG@186801|Clostridia,42FDS@68295|Thermoanaerobacterales	186801|Clostridia	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
k59_50705_1	1437824.BN940_01586	0.000117	50.4	COG1629@1|root,COG4771@2|Bacteria,1MUC1@1224|Proteobacteria,2VK0M@28216|Betaproteobacteria,3T28S@506|Alcaligenaceae	28216|Betaproteobacteria	P	COG4771 Outer membrane receptor for ferrienterochelin and colicins	-	-	-	ko:K02014,ko:K16087,ko:K16089	-	-	-	-	ko00000,ko02000	1.B.14,1.B.14.1,1.B.14.10,1.B.14.2	-	-	Plug,TonB_dep_Rec
k59_217735_1	593750.Metfor_1719	3.67e-128	377.0	COG1614@1|root,arCOG04360@2157|Archaea,2XU0D@28890|Euryarchaeota,2N95I@224756|Methanomicrobia	224756|Methanomicrobia	C	Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing growth on acetate as sole source of carbon and energy. The alpha-epsilon complex generates CO from CO(2), while the beta subunit (this protein) combines the CO with CoA and a methyl group to form acetyl-CoA. The methyl group, which is incorporated into acetyl-CoA, is transferred to the beta subunit by a corrinoid iron-sulfur protein (the gamma-delta complex)	cdhC	-	-	ko:K00193	ko00680,ko01120,ko01200,map00680,map01120,map01200	M00357,M00422	R09096,R10219	RC00004,RC00113,RC02977	ko00000,ko00001,ko00002,ko01000	-	-	-	CdhC
k59_134812_1	158189.SpiBuddy_0113	2.26e-64	209.0	COG0067@1|root,COG0067@2|Bacteria,2J777@203691|Spirochaetes	203691|Spirochaetes	E	PFAM Glutamine amidotransferases class-II	-	-	-	-	-	-	-	-	-	-	-	-	GATase_2
k59_142360_1	933262.AXAM01000002_gene543	1.95e-71	227.0	COG1916@1|root,COG1916@2|Bacteria,1MWJ0@1224|Proteobacteria,42P2H@68525|delta/epsilon subdivisions,2WJQM@28221|Deltaproteobacteria,2MI76@213118|Desulfobacterales	28221|Deltaproteobacteria	S	TIGRFAM TraB family protein	-	-	-	-	-	-	-	-	-	-	-	-	TraB
k59_179436_1	177437.HRM2_45270	2.04e-87	268.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,42MK5@68525|delta/epsilon subdivisions,2WJ3Z@28221|Deltaproteobacteria,2MI0N@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM Acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
k59_118817_1	1121413.JMKT01000008_gene1483	6.3e-64	218.0	COG1148@1|root,COG1148@2|Bacteria,1QUM4@1224|Proteobacteria,42MPP@68525|delta/epsilon subdivisions,2WJ3U@28221|Deltaproteobacteria,2M7SC@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	4Fe-4S ferredoxin iron-sulfur binding domain protein	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_7,Pyr_redox_2
k59_194573_1	397278.JOJN01000019_gene2333	0.000233	47.4	COG2132@1|root,COG2133@1|root,COG2982@1|root,COG3291@1|root,COG3401@1|root,COG4733@1|root,COG2132@2|Bacteria,COG2133@2|Bacteria,COG2982@2|Bacteria,COG3291@2|Bacteria,COG3401@2|Bacteria,COG4733@2|Bacteria,2HCWC@201174|Actinobacteria	201174|Actinobacteria	Q	PA14 domain	-	-	-	-	-	-	-	-	-	-	-	-	Malectin,PA14
k59_217745_2	443143.GM18_2495	3.15e-66	213.0	COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,42NES@68525|delta/epsilon subdivisions,2WJ0V@28221|Deltaproteobacteria,43TBZ@69541|Desulfuromonadales	28221|Deltaproteobacteria	U	PFAM type II secretion system	pilC	-	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
k59_134816_1	1125863.JAFN01000001_gene430	5.73e-51	168.0	COG1028@1|root,COG1028@2|Bacteria,1MU5Y@1224|Proteobacteria	1224|Proteobacteria	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	ko:K12420	ko00253,ko01056,ko01130,map00253,map01056,map01130	M00778	R06642,R09262,R09263,R09264	RC00029,RC00144	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	-	-	-	adh_short,adh_short_C2
k59_104332_1	1120919.AUBI01000003_gene1710	3.45e-24	100.0	COG1010@1|root,COG1010@2|Bacteria,1MU79@1224|Proteobacteria,2TQJQ@28211|Alphaproteobacteria,2JQ9W@204441|Rhodospirillales	204441|Rhodospirillales	H	Precorrin-3B	cobJ	-	2.1.1.131,3.7.1.12	ko:K05934,ko:K13541	ko00860,ko01100,map00860,map01100	-	R05180,R05809,R07772	RC00003,RC01293,RC01545,RC02097,RC03471	ko00000,ko00001,ko01000	-	-	-	CbiG_C,CbiG_N,TP_methylase
k59_74246_1	335543.Sfum_1328	3.07e-67	218.0	COG1453@1|root,COG1453@2|Bacteria,1RAU3@1224|Proteobacteria,43A0M@68525|delta/epsilon subdivisions,2X9UN@28221|Deltaproteobacteria,2MS7U@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	PFAM aldo keto reductase	-	-	-	ko:K07079	-	-	-	-	ko00000	-	-	-	Aldo_ket_red
k59_240763_1	391735.Veis_3561	6.3e-141	410.0	COG4948@1|root,COG4948@2|Bacteria,1MURK@1224|Proteobacteria,2VJR9@28216|Betaproteobacteria,4A9VX@80864|Comamonadaceae	28216|Betaproteobacteria	M	Mandelate racemase / muconate lactonizing enzyme, C-terminal domain	rspA	-	4.2.1.8	ko:K08323	ko00040,ko01100,map00040,map01100	M00061	R05606	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
k59_240763_2	1211115.ALIQ01000021_gene4558	1.8e-61	198.0	COG1802@1|root,COG1802@2|Bacteria,1MWG2@1224|Proteobacteria,2U3AK@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	transcriptional regulator	-	-	-	ko:K22293	-	-	-	-	ko00000,ko03000	-	-	-	FCD,GntR
k59_172761_1	1121468.AUBR01000012_gene2605	6.4e-44	156.0	COG0457@1|root,COG0491@1|root,COG0457@2|Bacteria,COG0491@2|Bacteria	2|Bacteria	GM	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B,TPR_16
k59_5052_1	1121447.JONL01000006_gene25	3.31e-110	335.0	28J96@1|root,2Z947@2|Bacteria,1R6TE@1224|Proteobacteria,42PZG@68525|delta/epsilon subdivisions,2WIKY@28221|Deltaproteobacteria,2M87N@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	PFAM Oligopeptide transporter OPT superfamily	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_149527_1	706587.Desti_3270	1.73e-52	187.0	COG2202@1|root,COG2203@1|root,COG2204@1|root,COG4191@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG2204@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MC4@68525|delta/epsilon subdivisions,2WIU5@28221|Deltaproteobacteria,2MQZQ@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
k59_51156_1	933262.AXAM01000010_gene1350	2.99e-71	233.0	COG1196@1|root,COG1196@2|Bacteria,1MUAQ@1224|Proteobacteria,42MN9@68525|delta/epsilon subdivisions,2WJZF@28221|Deltaproteobacteria,2MHU0@213118|Desulfobacterales	28221|Deltaproteobacteria	D	Required for chromosome condensation and partitioning	smc	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
k59_188393_1	1353531.AZNX01000008_gene606	1.96e-14	79.3	COG1529@1|root,COG1529@2|Bacteria,1QTTJ@1224|Proteobacteria,2TQVK@28211|Alphaproteobacteria,4BNUF@82115|Rhizobiaceae	28211|Alphaproteobacteria	C	Molybdopterin-binding domain of aldehyde dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
k59_82030_1	1265505.ATUG01000002_gene2194	8.4e-86	267.0	COG2768@1|root,COG2768@2|Bacteria,1MXMK@1224|Proteobacteria,42M2Z@68525|delta/epsilon subdivisions,2WIN6@28221|Deltaproteobacteria,2MI71@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Domain of unknown function (DUF362)	-	-	-	ko:K07138	-	-	-	-	ko00000	-	-	-	DUF362,Fer4,Fer4_4,Fer4_6,Fer4_7
k59_225605_1	1406840.Q763_07425	3.27e-24	100.0	COG1044@1|root,COG1044@2|Bacteria,4NH6I@976|Bacteroidetes,1HXDW@117743|Flavobacteriia,2NU1K@237|Flavobacterium	976|Bacteroidetes	M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	-	-	2.3.1.191	ko:K02536	ko00540,ko01100,map00540,map01100	M00060	R04550	RC00039,RC00166	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hexapep,Hexapep_2,LpxD
k59_225605_2	1121396.KB893118_gene3101	6.27e-76	241.0	COG1032@1|root,COG1032@2|Bacteria,1MY2Y@1224|Proteobacteria,42NG3@68525|delta/epsilon subdivisions,2WJ95@28221|Deltaproteobacteria,2MJ57@213118|Desulfobacterales	28221|Deltaproteobacteria	C	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,DUF4070,Radical_SAM
k59_233955_1	1121405.dsmv_0689	8.24e-58	185.0	COG2197@1|root,COG2197@2|Bacteria,1MWGM@1224|Proteobacteria,42R03@68525|delta/epsilon subdivisions,2WMTZ@28221|Deltaproteobacteria,2MJ7X@213118|Desulfobacterales	28221|Deltaproteobacteria	T	PFAM response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
k59_112288_1	56780.SYN_02429	4.32e-12	62.8	COG3462@1|root,COG3462@2|Bacteria,1Q55M@1224|Proteobacteria,42WZ8@68525|delta/epsilon subdivisions,2WSP8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Short C-terminal domain	-	-	-	ko:K08982	-	-	-	-	ko00000	-	-	-	SHOCT
k59_135255_1	909663.KI867150_gene1152	2.92e-97	298.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,42NB6@68525|delta/epsilon subdivisions,2WIWE@28221|Deltaproteobacteria,2MQU0@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	PDZ domain (Also known as DHR or GLGF)	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
k59_51169_1	1088721.NSU_3004	9.27e-63	206.0	COG1236@1|root,COG1236@2|Bacteria,1MUDD@1224|Proteobacteria,2TVFM@28211|Alphaproteobacteria,2K114@204457|Sphingomonadales	204457|Sphingomonadales	J	Metallo-beta-lactamase superfamily domain	-	-	-	ko:K07576	-	-	-	-	ko00000	-	-	-	Beta-Casp,Lactamase_B,RMMBL
k59_82037_1	1121396.KB893079_gene821	1.89e-54	188.0	COG0761@1|root,COG0761@2|Bacteria,1MU7G@1224|Proteobacteria,42MJK@68525|delta/epsilon subdivisions,2WJ8V@28221|Deltaproteobacteria,2MI49@213118|Desulfobacterales	28221|Deltaproteobacteria	IM	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis	ispH	-	1.17.7.4	ko:K02945,ko:K03527	ko00900,ko01100,ko01110,ko01130,ko03010,map00900,map01100,map01110,map01130,map03010	M00096,M00178	R05884,R08210	RC01137,RC01487	br01610,ko00000,ko00001,ko00002,ko01000,ko03011	-	-	-	LYTB,UbiA
k59_43377_1	56780.SYN_01263	2.56e-34	127.0	COG1127@1|root,COG2199@1|root,COG1127@2|Bacteria,COG2199@2|Bacteria,1MUSD@1224|Proteobacteria,42NI4@68525|delta/epsilon subdivisions,2WKRT@28221|Deltaproteobacteria,2MQX9@213462|Syntrophobacterales	28221|Deltaproteobacteria	Q	ABC transporter	-	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran,GGDEF
k59_172766_1	933262.AXAM01000040_gene1226	5.12e-80	265.0	COG2844@1|root,COG2844@2|Bacteria,1MV54@1224|Proteobacteria,42MN5@68525|delta/epsilon subdivisions,2WINN@28221|Deltaproteobacteria,2MI1W@213118|Desulfobacterales	28221|Deltaproteobacteria	O	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen	glnD	-	2.7.7.59	ko:K00990	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	-	-	-	ACT,DUF294,GlnD_UR_UTase,GlnE,HD,NTP_transf_2
k59_66295_1	290317.Cpha266_1571	1.91e-61	194.0	COG1592@1|root,COG1592@2|Bacteria,1FE9N@1090|Chlorobi	1090|Chlorobi	C	PFAM Rubrerythrin	-	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
k59_195002_1	251229.Chro_4605	1.81e-75	236.0	28NSU@1|root,2ZBRQ@2|Bacteria,1G22S@1117|Cyanobacteria	1117|Cyanobacteria	S	Methyltransferase FkbM domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21
k59_51170_1	1121451.DESAM_21269	1.4e-39	152.0	COG0457@1|root,COG0457@2|Bacteria,1NNJ6@1224|Proteobacteria,42PBD@68525|delta/epsilon subdivisions,2WKWJ@28221|Deltaproteobacteria,2M91R@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2,TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8
k59_74279_1	754476.Q7A_2984	3.07e-08	58.5	COG1639@1|root,COG1639@2|Bacteria,1RCW6@1224|Proteobacteria,1S3XV@1236|Gammaproteobacteria,463MA@72273|Thiotrichales	72273|Thiotrichales	T	HDOD domain	-	-	-	-	-	-	-	-	-	-	-	-	HDOD
k59_225618_2	96561.Dole_0802	2.25e-35	122.0	COG0636@1|root,COG0636@2|Bacteria,1NAIE@1224|Proteobacteria,42UFU@68525|delta/epsilon subdivisions,2WR59@28221|Deltaproteobacteria,2MKI0@213118|Desulfobacterales	28221|Deltaproteobacteria	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	-	-	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
k59_225618_3	96561.Dole_0801	5.54e-24	96.3	COG0356@1|root,COG0356@2|Bacteria,1MV87@1224|Proteobacteria,42NZS@68525|delta/epsilon subdivisions,2WINI@28221|Deltaproteobacteria,2MI5U@213118|Desulfobacterales	28221|Deltaproteobacteria	C	it plays a direct role in the translocation of protons across the membrane	-	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
k59_135272_1	1232410.KI421419_gene2478	2.2e-127	380.0	COG1048@1|root,COG1048@2|Bacteria,1MU9T@1224|Proteobacteria,42N5M@68525|delta/epsilon subdivisions,2WIIV@28221|Deltaproteobacteria,43RYP@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Aconitase C-terminal domain	-	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2763	Aconitase,Aconitase_C
k59_172781_1	1487923.DP73_16475	1.29e-59	197.0	COG0389@1|root,COG0389@2|Bacteria,1TP42@1239|Firmicutes,24855@186801|Clostridia,2601Y@186807|Peptococcaceae	186801|Clostridia	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	dinB	-	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
k59_66303_1	1232437.KL662064_gene4059	8.61e-73	236.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42NWT@68525|delta/epsilon subdivisions,2X5DA@28221|Deltaproteobacteria,2MMYJ@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Sigma-54 interaction domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
k59_157763_1	644282.Deba_2183	1.75e-45	164.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2WJN5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_157766_1	933262.AXAM01000029_gene2750	2.94e-73	224.0	COG0440@1|root,COG0440@2|Bacteria,1RAGN@1224|Proteobacteria,42RRU@68525|delta/epsilon subdivisions,2WNBY@28221|Deltaproteobacteria,2MJMK@213118|Desulfobacterales	28221|Deltaproteobacteria	E	TIGRFAM acetolactate synthase, small subunit	ilvN	-	2.2.1.6	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,ACT_5,ALS_ss_C
k59_179978_1	102125.Xen7305DRAFT_00039590	5.98e-30	112.0	2ERVI@1|root,33JEQ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_36540_1	1121456.ATVA01000001_gene3072	7.79e-40	142.0	2AFUA@1|root,315WQ@2|Bacteria,1NHGB@1224|Proteobacteria,42TSA@68525|delta/epsilon subdivisions,2WQKD@28221|Deltaproteobacteria,2M9ZQ@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Putative transmembrane protein (Alph_Pro_TM)	-	-	-	-	-	-	-	-	-	-	-	-	Alph_Pro_TM
k59_112327_1	207559.Dde_1552	2.17e-38	145.0	COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,42P4S@68525|delta/epsilon subdivisions,2WJXD@28221|Deltaproteobacteria,2MG1R@213115|Desulfovibrionales	28221|Deltaproteobacteria	K	PFAM sigma-54 factor interaction domain-containing protein	-	-	-	ko:K03721	-	-	-	-	ko00000,ko03000	-	-	-	HTH_8,PAS,PAS_4,Sigma54_activat
k59_119391_1	879212.DespoDRAFT_01601	7.92e-27	116.0	COG4775@1|root,COG4775@2|Bacteria,1R75N@1224|Proteobacteria,42MIG@68525|delta/epsilon subdivisions,2WMI0@28221|Deltaproteobacteria,2MIJA@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Surface antigen	-	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
k59_9647_1	1232437.KL661985_gene3580	2.66e-125	365.0	COG0834@1|root,COG0834@2|Bacteria,1MV5D@1224|Proteobacteria,43BDC@68525|delta/epsilon subdivisions,2WK43@28221|Deltaproteobacteria,2MHPC@213118|Desulfobacterales	28221|Deltaproteobacteria	ET	Bacterial extracellular solute-binding proteins, family 3	aapJ	-	-	ko:K09969	ko02010,map02010	M00232	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3.18,3.A.1.3.7,3.A.1.3.8	-	-	SBP_bac_3
k59_115522_1	1121396.KB893133_gene652	0.000432	45.8	2E0C3@1|root,32VZ5@2|Bacteria,1N5NQ@1224|Proteobacteria,42WJC@68525|delta/epsilon subdivisions,2WSB2@28221|Deltaproteobacteria,2MM62@213118|Desulfobacterales	28221|Deltaproteobacteria	S	PEP-CTERM motif	-	-	-	-	-	-	-	-	-	-	-	-	VPEP
k59_146073_1	690850.Desaf_2299	3.69e-10	65.9	COG5616@1|root,COG5616@2|Bacteria,1RBBE@1224|Proteobacteria,42QR8@68525|delta/epsilon subdivisions,2WN1X@28221|Deltaproteobacteria,2M8NQ@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	cAMP biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	CsgG,VCBS
k59_70192_1	1167006.UWK_02137	1.67e-47	165.0	COG2204@1|root,COG4191@1|root,COG2204@2|Bacteria,COG4191@2|Bacteria,1R891@1224|Proteobacteria,42P2C@68525|delta/epsilon subdivisions,2WJZT@28221|Deltaproteobacteria,2MIG9@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,Response_reg
k59_199132_1	1121422.AUMW01000002_gene2176	7.08e-20	88.2	COG0806@1|root,COG0806@2|Bacteria,1V6HD@1239|Firmicutes,24I1G@186801|Clostridia,2623V@186807|Peptococcaceae	186801|Clostridia	J	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes	rimM	-	-	ko:K02860	-	-	-	-	ko00000,ko03009	-	-	-	PRC,RimM
k59_206804_1	338966.Ppro_2890	1.21e-48	171.0	COG1797@1|root,COG1797@2|Bacteria,1MV7Z@1224|Proteobacteria,42M8T@68525|delta/epsilon subdivisions,2WIXE@28221|Deltaproteobacteria,43T2Y@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source	cbiA	-	6.3.5.11,6.3.5.9	ko:K02224	ko00860,ko01100,ko01120,map00860,map01100,map01120	-	R05224,R05815	RC00010,RC01301	ko00000,ko00001,ko01000	-	-	iAF987.Gmet_0470	CPT,CbiA,GATase_3
k59_85280_1	1307759.JOMJ01000003_gene1397	3.27e-06	48.1	COG4117@1|root,COG4117@2|Bacteria,1R5GN@1224|Proteobacteria,42QVP@68525|delta/epsilon subdivisions,2WMT7@28221|Deltaproteobacteria,2M7S8@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	Prokaryotic cytochrome b561	cbcB	-	-	-	-	-	-	-	-	-	-	-	Ni_hydr_CYTB
k59_85280_2	1265505.ATUG01000002_gene2120	3.85e-99	312.0	COG3264@1|root,COG3264@2|Bacteria,1MWSA@1224|Proteobacteria,42N78@68525|delta/epsilon subdivisions,2WM0M@28221|Deltaproteobacteria,2MHVS@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Mechanosensitive ion channel	mscS-2	-	-	-	-	-	-	-	-	-	-	-	MS_channel
k59_138606_1	357808.RoseRS_0444	6.96e-99	304.0	COG3385@1|root,COG3385@2|Bacteria,2G9A6@200795|Chloroflexi	200795|Chloroflexi	L	PFAM transposase, IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
k59_123368_1	1042156.CXIVA_06860	1.33e-12	73.9	COG0493@1|root,COG0493@2|Bacteria,1TQ1A@1239|Firmicutes,248EK@186801|Clostridia,36FQY@31979|Clostridiaceae	186801|Clostridia	C	Oxidoreductase	sfrB	-	1.17.1.10	ko:K15022	ko00680,ko00720,ko01120,ko01200,map00680,map00720,map01120,map01200	M00377	R00134	RC02796	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_20,NADH_4Fe-4S,Pyr_redox_2
k59_146083_1	765912.Thimo_0459	1.89e-72	231.0	COG3344@1|root,COG3344@2|Bacteria,1MVI1@1224|Proteobacteria,1RQP7@1236|Gammaproteobacteria,1WVZP@135613|Chromatiales	135613|Chromatiales	L	reverse transcriptase	-	-	-	-	-	-	-	-	-	-	-	-	RVT_1
k59_77959_1	706587.Desti_3270	1.67e-116	378.0	COG2202@1|root,COG2203@1|root,COG2204@1|root,COG4191@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG2204@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MC4@68525|delta/epsilon subdivisions,2WIU5@28221|Deltaproteobacteria,2MQZQ@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
k59_214209_2	1394178.AWOO02000036_gene8915	4.92e-31	123.0	COG0559@1|root,COG0559@2|Bacteria,2GKAR@201174|Actinobacteria,4EPNF@85012|Streptosporangiales	201174|Actinobacteria	U	Branched-chain amino acid transport system / permease component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_2
k59_184583_1	641491.DND132_0110	1.01e-08	58.5	COG1286@1|root,COG1286@2|Bacteria,1RJE1@1224|Proteobacteria,42SCW@68525|delta/epsilon subdivisions,2WPNX@28221|Deltaproteobacteria,2MDHW@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	PFAM Colicin V production protein	-	-	-	ko:K03558	-	-	-	-	ko00000	-	-	-	Colicin_V
k59_25249_1	596152.DesU5LDRAFT_1490	6.24e-164	485.0	COG0210@1|root,COG0210@2|Bacteria,1NTDR@1224|Proteobacteria,42Z5K@68525|delta/epsilon subdivisions,2WTHU@28221|Deltaproteobacteria,2M95F@213115|Desulfovibrionales	28221|Deltaproteobacteria	L	UvrD-like helicase C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	UvrD-helicase,UvrD_C
k59_139190_1	1167006.UWK_01451	1.18e-65	206.0	COG1305@1|root,COG1305@2|Bacteria,1R4TK@1224|Proteobacteria,42QWS@68525|delta/epsilon subdivisions,2WN7P@28221|Deltaproteobacteria,2MK1X@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
k59_214691_1	1265505.ATUG01000002_gene2074	2.28e-41	152.0	COG1109@1|root,COG1109@2|Bacteria,1QUGD@1224|Proteobacteria,43BUU@68525|delta/epsilon subdivisions,2WKYP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	phosphoglucomutase phosphomannomutase alpha beta alpha domain I	-	-	5.4.2.2,5.4.2.8	ko:K01835,ko:K01840	ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00114,M00549	R00959,R01057,R01818,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
k59_131485_1	1121445.ATUZ01000011_gene432	2.49e-08	55.5	COG4753@1|root,COG4753@2|Bacteria,1NKNV@1224|Proteobacteria,43CQT@68525|delta/epsilon subdivisions,2X7YC@28221|Deltaproteobacteria,2MD5T@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_237665_1	439235.Dalk_1966	6.01e-92	284.0	COG3604@1|root,COG3604@2|Bacteria,1QTT3@1224|Proteobacteria,42Y69@68525|delta/epsilon subdivisions,2WJ5F@28221|Deltaproteobacteria,2MI66@213118|Desulfobacterales	28221|Deltaproteobacteria	KT	PFAM sigma-54 factor interaction domain-containing protein	-	-	-	ko:K02584	ko02020,map02020	-	-	-	ko00000,ko00001,ko03000	-	-	-	GAF,GAF_2,HTH_8,Sigma54_activat
k59_101182_1	118168.MC7420_6205	3.39e-27	114.0	COG4225@1|root,COG4225@2|Bacteria	2|Bacteria	S	unsaturated chondroitin disaccharide hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	Alginate_lyase,BNR_4
k59_2345_2	1265505.ATUG01000002_gene2622	4.9e-72	221.0	COG0437@1|root,COG0437@2|Bacteria,1MU5T@1224|Proteobacteria,42R9D@68525|delta/epsilon subdivisions,2WN5Q@28221|Deltaproteobacteria,2MJN0@213118|Desulfobacterales	28221|Deltaproteobacteria	C	4Fe-4S dicluster domain	-	-	-	ko:K00124	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001	-	-	-	Fer4_11,Fer4_4,Fer4_7
k59_78509_1	3847.GLYMA13G11980.1	3.54e-81	271.0	2CUMQ@1|root,2RN4M@2759|Eukaryota,37U2D@33090|Viridiplantae,3GX5D@35493|Streptophyta,4JTXP@91835|fabids	35493|Streptophyta	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_154394_1	743722.Sph21_3062	0.000603	47.0	COG0457@1|root,COG0457@2|Bacteria,4PM5D@976|Bacteroidetes,1J0VV@117747|Sphingobacteriia	976|Bacteroidetes	S	TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_19,TPR_6,TPR_8
k59_70618_1	316067.Geob_2508	4.14e-71	226.0	COG0709@1|root,COG0709@2|Bacteria,1MWFG@1224|Proteobacteria,42MC3@68525|delta/epsilon subdivisions,2WK3M@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	Synthesizes selenophosphate from selenide and ATP	selD	-	2.7.9.3	ko:K01008	ko00450,ko01100,map00450,map01100	-	R03595	RC00002,RC02878	ko00000,ko00001,ko01000,ko03016	-	-	-	AIRS,AIRS_C
k59_176870_2	1293054.HSACCH_00119	1.6e-49	164.0	COG3290@1|root,COG3290@2|Bacteria,1UJ85@1239|Firmicutes,25EY1@186801|Clostridia,3WBTR@53433|Halanaerobiales	186801|Clostridia	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
k59_222531_1	1123276.KB893272_gene2436	8.23e-47	164.0	COG3385@1|root,COG3385@2|Bacteria,4P02Y@976|Bacteroidetes,47TUA@768503|Cytophagia	976|Bacteroidetes	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
k59_191980_1	639283.Snov_3262	9.96e-75	235.0	COG1638@1|root,COG1638@2|Bacteria,1MVHC@1224|Proteobacteria,2TRZE@28211|Alphaproteobacteria,3EY6T@335928|Xanthobacteraceae	28211|Alphaproteobacteria	G	Bacterial extracellular solute-binding protein, family 7	MA20_38040	GO:0003674,GO:0005488,GO:0006810,GO:0006950,GO:0006974,GO:0008150,GO:0008643,GO:0009987,GO:0030246,GO:0033554,GO:0034219,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0055085,GO:0071702	-	ko:K21395	-	-	-	-	ko00000,ko02000	2.A.56.1	-	-	DctP
k59_214705_1	177437.HRM2_36120	1.64e-64	199.0	COG0096@1|root,COG0096@2|Bacteria,1RDG3@1224|Proteobacteria,42SF6@68525|delta/epsilon subdivisions,2WPDP@28221|Deltaproteobacteria,2MJZV@213118|Desulfobacterales	28221|Deltaproteobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit	rpsH	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02994	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S8
k59_85809_1	933262.AXAM01000021_gene478	1.74e-99	300.0	COG0438@1|root,COG0438@2|Bacteria,1NA28@1224|Proteobacteria,42NZA@68525|delta/epsilon subdivisions,2WK1T@28221|Deltaproteobacteria,2MIH3@213118|Desulfobacterales	28221|Deltaproteobacteria	M	PFAM Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	DUF3524,Glycos_transf_1
k59_131501_1	96561.Dole_0660	1.78e-41	149.0	COG3039@1|root,COG3039@2|Bacteria,1QQ9Q@1224|Proteobacteria,42S7X@68525|delta/epsilon subdivisions,2WNJ2@28221|Deltaproteobacteria,2MJG4@213118|Desulfobacterales	28221|Deltaproteobacteria	L	PFAM transposase IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DUF772
k59_139213_1	880072.Desac_0500	4.92e-160	459.0	COG1804@1|root,COG1804@2|Bacteria,1NWFC@1224|Proteobacteria,4300F@68525|delta/epsilon subdivisions,2X2A6@28221|Deltaproteobacteria,2MRS4@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	L-carnitine dehydratase bile acid-inducible protein F	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
k59_108571_1	580332.Slit_2788	1.15e-40	147.0	COG2801@1|root,COG2801@2|Bacteria,1MVXQ@1224|Proteobacteria,2VQF1@28216|Betaproteobacteria	28216|Betaproteobacteria	L	PFAM Integrase catalytic region	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve
k59_214709_1	338963.Pcar_2468	8.06e-57	188.0	COG0477@1|root,COG2814@2|Bacteria,1PFB3@1224|Proteobacteria,42N9W@68525|delta/epsilon subdivisions,2WJW0@28221|Deltaproteobacteria,43TQH@69541|Desulfuromonadales	28221|Deltaproteobacteria	EGP	MFS_1 like family	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
k59_214709_2	555088.DealDRAFT_0594	7.96e-14	70.5	COG0479@1|root,COG0479@2|Bacteria,1TP17@1239|Firmicutes,24AN0@186801|Clostridia	186801|Clostridia	C	TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein	-	-	1.3.5.1,1.3.5.4	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_3,Fer4_8
k59_55777_1	1120971.AUCA01000003_gene1371	2.34e-12	73.2	COG0144@1|root,COG0144@2|Bacteria,1TPGQ@1239|Firmicutes,4HCHQ@91061|Bacilli,2784D@186823|Alicyclobacillaceae	91061|Bacilli	J	RNA-binding PUA-like domain of methyltransferase RsmF	rsmF	-	-	-	-	-	-	-	-	-	-	-	Methyltr_RsmB-F,Methyltr_RsmF_N,Methyltranf_PUA,RsmF_methylt_CI
k59_40463_1	933262.AXAM01000077_gene1698	5.99e-40	134.0	2APA5@1|root,31EC7@2|Bacteria,1RHMQ@1224|Proteobacteria,42UND@68525|delta/epsilon subdivisions,2WQK4@28221|Deltaproteobacteria,2MM23@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_40463_2	1121405.dsmv_0507	1.47e-11	65.5	COG2204@1|root,COG2204@2|Bacteria,1PAPS@1224|Proteobacteria,42YHK@68525|delta/epsilon subdivisions,2WUDF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Bacterial regulatory protein, Fis family	-	-	-	ko:K07713	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
k59_70635_1	634497.HAH_0761	2.15e-06	55.5	COG1078@1|root,arCOG04430@2157|Archaea,2XUT7@28890|Euryarchaeota,23S02@183963|Halobacteria	183963|Halobacteria	S	COG1078 HD superfamily phosphohydrolases	-	-	-	ko:K06885	-	-	-	-	ko00000	-	-	-	HD
k59_146522_1	1121403.AUCV01000004_gene2061	6.76e-16	74.7	COG5608@1|root,COG5608@2|Bacteria,1Q3JI@1224|Proteobacteria,42XEN@68525|delta/epsilon subdivisions,2WSWH@28221|Deltaproteobacteria,2MQ1I@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Late embryogenesis abundant protein	-	-	-	-	-	-	-	-	-	-	-	-	LEA_2
k59_214711_1	706587.Desti_0410	5.44e-15	79.0	COG1638@1|root,COG1638@2|Bacteria,1MVHI@1224|Proteobacteria,42QBT@68525|delta/epsilon subdivisions,2WJK6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	Bacterial extracellular solute-binding protein, family 7	-	-	-	-	-	-	-	-	-	-	-	-	DctP
k59_101209_1	1232437.KL661988_gene276	1.46e-20	90.1	COG0589@1|root,COG0745@1|root,COG0589@2|Bacteria,COG0745@2|Bacteria,1MZPD@1224|Proteobacteria,42U2Y@68525|delta/epsilon subdivisions,2WQ1I@28221|Deltaproteobacteria,2MQ25@213118|Desulfobacterales	28221|Deltaproteobacteria	KT	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Usp
k59_101209_2	690850.Desaf_1237	2.9e-05	49.7	COG3267@1|root,COG3267@2|Bacteria,1MU3G@1224|Proteobacteria,42NNX@68525|delta/epsilon subdivisions,2WJ9P@28221|Deltaproteobacteria,2MD1V@213115|Desulfovibrionales	28221|Deltaproteobacteria	U	AAA domain	-	-	-	ko:K02450	-	M00331	-	-	ko00000,ko00002,ko02044	9.B.42	-	-	AAA_22
k59_230039_1	933262.AXAM01000031_gene3013	1.1e-72	232.0	COG0477@1|root,COG2814@2|Bacteria,1MVSH@1224|Proteobacteria,42NA4@68525|delta/epsilon subdivisions,2WKTU@28221|Deltaproteobacteria,2MHYA@213118|Desulfobacterales	28221|Deltaproteobacteria	EGP	PFAM Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_1_like,MFS_3,Sugar_tr
k59_222548_1	177437.HRM2_31130	6.12e-81	258.0	COG1960@1|root,COG1960@2|Bacteria,1MU20@1224|Proteobacteria,42MUH@68525|delta/epsilon subdivisions,2WJ16@28221|Deltaproteobacteria,2MIWK@213118|Desulfobacterales	28221|Deltaproteobacteria	I	Acetyl-CoA dehydrogenase C-terminal like	-	-	-	ko:K09456	-	-	-	-	ko00000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_C,Acyl-CoA_dh_M,Acyl-CoA_dh_N,AcylCoA_DH_N
k59_176889_1	177437.HRM2_20940	1.71e-151	447.0	COG4666@1|root,COG4666@2|Bacteria,1MUNB@1224|Proteobacteria,42MEV@68525|delta/epsilon subdivisions,2WK2S@28221|Deltaproteobacteria,2MIMQ@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF3394)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3394,DctM
k59_10257_1	909663.KI867150_gene2010	5.16e-40	145.0	COG3328@1|root,COG3328@2|Bacteria,1MU4P@1224|Proteobacteria,42S30@68525|delta/epsilon subdivisions,2WQ5S@28221|Deltaproteobacteria,2MRTS@213462|Syntrophobacterales	28221|Deltaproteobacteria	L	Transposase, Mutator family	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_mut
k59_40470_2	338969.Rfer_3520	2.81e-36	132.0	COG1309@1|root,COG1309@2|Bacteria,1R6RX@1224|Proteobacteria,2VKE3@28216|Betaproteobacteria,4ABAH@80864|Comamonadaceae	28216|Betaproteobacteria	K	PFAM regulatory protein TetR	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
k59_230042_2	573413.Spirs_3836	1.41e-14	75.1	arCOG07533@1|root,2ZF5I@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4386)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4386
k59_199682_1	452637.Oter_1799	9.56e-64	199.0	2C7QB@1|root,341QI@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_131506_1	1232437.KL661988_gene210	1.74e-24	100.0	COG1092@1|root,COG1092@2|Bacteria,1QW1V@1224|Proteobacteria,42Q3P@68525|delta/epsilon subdivisions,2WJXM@28221|Deltaproteobacteria,2MHVR@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Belongs to the methyltransferase superfamily	-	-	2.1.1.173,2.1.1.191,2.1.1.264	ko:K06969,ko:K12297	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
k59_131506_2	1307761.L21SP2_0622	7.24e-40	139.0	COG3012@1|root,COG3012@2|Bacteria,2J7G8@203691|Spirochaetes	203691|Spirochaetes	U	SEC-C domain protein	-	-	-	ko:K09858	-	-	-	-	ko00000	-	-	-	SEC-C
k59_108577_1	1125863.JAFN01000001_gene613	1.87e-101	309.0	COG0677@1|root,COG0677@2|Bacteria,1MUC6@1224|Proteobacteria,42M4F@68525|delta/epsilon subdivisions,2WKK3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM UDP-glucose GDP-mannose dehydrogenase	-	-	1.1.1.136	ko:K02474,ko:K13015	ko00520,map00520	-	R00421,R06894	RC00291	ko00000,ko00001,ko01000,ko01005	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
k59_17527_1	1121413.JMKT01000009_gene2214	3.26e-28	105.0	2DP9Z@1|root,3316S@2|Bacteria,1R1CI@1224|Proteobacteria,42V8N@68525|delta/epsilon subdivisions,2X8FK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_124081_1	933262.AXAM01000002_gene558	2.17e-140	419.0	COG0466@1|root,COG0466@2|Bacteria,1MUV2@1224|Proteobacteria,42M9W@68525|delta/epsilon subdivisions,2WJ29@28221|Deltaproteobacteria,2MHRD@213118|Desulfobacterales	28221|Deltaproteobacteria	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	-	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
k59_237685_1	218284.CCDN010000008_gene4139	1.21e-49	171.0	COG3547@1|root,COG3547@2|Bacteria,1V427@1239|Firmicutes,4HGY6@91061|Bacilli,1ZERT@1386|Bacillus	91061|Bacilli	L	PFAM transposase IS116 IS110 IS902 family	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_116034_1	909663.KI867150_gene229	1.21e-19	81.6	2E9PU@1|root,333W6@2|Bacteria,1N6VC@1224|Proteobacteria,42WJ7@68525|delta/epsilon subdivisions,2WRB6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_85830_1	944480.ATUV01000001_gene1527	1.26e-13	72.8	COG0247@1|root,COG0247@2|Bacteria,1MWTK@1224|Proteobacteria,42MMF@68525|delta/epsilon subdivisions,2WJ1F@28221|Deltaproteobacteria,2M6A8@213113|Desulfurellales	28221|Deltaproteobacteria	C	4Fe-4S dicluster domain	larF	-	-	ko:K11473	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001	-	-	-	CCG,Fer4_8
k59_146537_1	289376.THEYE_A1932	1.79e-48	161.0	COG0461@1|root,COG0461@2|Bacteria,3J0T8@40117|Nitrospirae	40117|Nitrospirae	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	pyrE	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran
k59_32836_1	1232437.KL662001_gene4589	2.51e-55	194.0	COG2197@1|root,COG4191@1|root,COG2197@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42PZ5@68525|delta/epsilon subdivisions,2WM1A@28221|Deltaproteobacteria,2MJZM@213118|Desulfobacterales	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4,PAS_9,Response_reg
k59_222564_1	207559.Dde_0803	1.55e-31	122.0	COG2241@1|root,COG2242@1|root,COG2241@2|Bacteria,COG2242@2|Bacteria,1MVJX@1224|Proteobacteria,42MEZ@68525|delta/epsilon subdivisions,2WIUW@28221|Deltaproteobacteria,2M8JD@213115|Desulfovibrionales	28221|Deltaproteobacteria	H	Precorrin-6y C5,15-methyltransferase (Decarboxylating), CbiE subunit	cbiET	-	2.1.1.132	ko:K00595	ko00860,ko01100,map00860,map01100	-	R05149	RC00003,RC01279	ko00000,ko00001,ko01000	-	-	-	Cons_hypoth95,Methyltransf_31,Methyltransf_4,PCMT,TP_methylase
k59_101231_2	335543.Sfum_3646	2.28e-36	128.0	COG0799@1|root,COG0799@2|Bacteria,1MZEF@1224|Proteobacteria,42VN5@68525|delta/epsilon subdivisions,2WRGG@28221|Deltaproteobacteria,2MQM6@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation	rsfS	-	-	ko:K09710	-	-	-	-	ko00000,ko03009	-	-	-	RsfS
k59_207347_2	1200567.JNKD01000009_gene329	2.63e-14	72.8	COG0187@1|root,COG0187@2|Bacteria,1MVKT@1224|Proteobacteria,1RNB2@1236|Gammaproteobacteria,1Y43E@135624|Aeromonadales	135624|Aeromonadales	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
k59_146540_1	335543.Sfum_3313	1.64e-66	213.0	COG0583@1|root,COG0583@2|Bacteria,1MWVU@1224|Proteobacteria,42PMQ@68525|delta/epsilon subdivisions,2WKB8@28221|Deltaproteobacteria,2MQEZ@213462|Syntrophobacterales	28221|Deltaproteobacteria	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
k59_199703_1	1121396.KB893077_gene740	7.78e-115	335.0	COG2152@1|root,COG2152@2|Bacteria,1MX8M@1224|Proteobacteria,42QDF@68525|delta/epsilon subdivisions,2WMG5@28221|Deltaproteobacteria,2MJJI@213118|Desulfobacterales	28221|Deltaproteobacteria	G	beta-1,4-mannooligosaccharide phosphorylase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_130
k59_199703_2	1121396.KB893077_gene741	4.19e-192	548.0	COG2152@1|root,COG2152@2|Bacteria,1MX8M@1224|Proteobacteria,42YYU@68525|delta/epsilon subdivisions,2WU8G@28221|Deltaproteobacteria,2MN6U@213118|Desulfobacterales	28221|Deltaproteobacteria	G	Pfam:DUF377	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_130
k59_176894_1	1069080.KB913028_gene1851	8.07e-16	80.9	COG1561@1|root,COG1561@2|Bacteria,1TQHJ@1239|Firmicutes,4H2DA@909932|Negativicutes	909932|Negativicutes	S	TIGR00255 family	-	-	-	-	-	-	-	-	-	-	-	-	DUF1732,YicC_N
k59_184654_2	931626.Awo_c05190	0.000809	42.7	COG5012@1|root,COG5012@2|Bacteria,1V1P0@1239|Firmicutes,24G08@186801|Clostridia,25YJ3@186806|Eubacteriaceae	186801|Clostridia	S	B12 binding domain	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,B12-binding_2
k59_192016_1	234267.Acid_4507	1.21e-78	249.0	COG0366@1|root,COG0366@2|Bacteria,3Y2P1@57723|Acidobacteria	57723|Acidobacteria	G	Alpha amylase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase
k59_116051_1	269797.Mbar_A2511	2.69e-26	110.0	COG5659@1|root,arCOG07789@2157|Archaea,2Y4ED@28890|Euryarchaeota	28890|Euryarchaeota	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_5
k59_40518_2	933262.AXAM01000004_gene2411	6.36e-48	166.0	COG0053@1|root,COG1433@1|root,COG0053@2|Bacteria,COG1433@2|Bacteria,1MUDS@1224|Proteobacteria,42NCJ@68525|delta/epsilon subdivisions,2WKDR@28221|Deltaproteobacteria,2MJE3@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Dimerisation domain of Zinc Transporter	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,Nitro_FeMo-Co,ZT_dimer
k59_70656_1	589924.Ferp_0086	2.32e-146	432.0	COG0574@1|root,arCOG01114@2157|Archaea,2XVIT@28890|Euryarchaeota	28890|Euryarchaeota	G	PEP-utilising enzyme, mobile domain	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers
k59_199709_1	1191523.MROS_1011	8.59e-63	208.0	COG3547@1|root,COG3547@2|Bacteria	2|Bacteria	L	Transposase (IS116 IS110 IS902 family)	-	-	-	ko:K07486	-	-	-	-	ko00000	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_2398_2	106370.Francci3_1018	1.21e-68	225.0	COG3335@1|root,COG3415@1|root,COG3335@2|Bacteria,COG3415@2|Bacteria,2GJQI@201174|Actinobacteria,4ERUS@85013|Frankiales	201174|Actinobacteria	L	manually curated	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,HTH_32
k59_222581_1	335543.Sfum_3724	4.17e-84	269.0	COG0077@1|root,COG2876@1|root,COG0077@2|Bacteria,COG2876@2|Bacteria,1QVAD@1224|Proteobacteria,42MU4@68525|delta/epsilon subdivisions,2WJ8Y@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	PFAM DAHP synthetase I KDSA	-	-	2.5.1.54,5.4.99.5	ko:K03856,ko:K04516	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022,M00024,M00025	R01715,R01826	RC00435,RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,CM_2,DAHP_synth_1,PDT
k59_241022_1	765913.ThidrDRAFT_2237	5.12e-24	106.0	COG2203@1|root,COG4191@1|root,COG5000@1|root,COG5002@1|root,COG2203@2|Bacteria,COG4191@2|Bacteria,COG5000@2|Bacteria,COG5002@2|Bacteria,1RCM9@1224|Proteobacteria,1RN52@1236|Gammaproteobacteria,1X0NW@135613|Chromatiales	135613|Chromatiales	T	Signal transduction histidine kinase, subgroup 1, dimerisation phosphoacceptor region	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,PAS_9
k59_234244_1	717231.Flexsi_1734	6.72e-78	259.0	COG0841@1|root,COG0841@2|Bacteria,2GESU@200930|Deferribacteres	200930|Deferribacteres	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
k59_59727_2	1265505.ATUG01000003_gene789	5.99e-79	250.0	COG3666@1|root,COG3666@2|Bacteria,1N3QR@1224|Proteobacteria,42N7X@68525|delta/epsilon subdivisions,2WMM9@28221|Deltaproteobacteria,2MMU3@213118|Desulfobacterales	28221|Deltaproteobacteria	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_6,DUF772
k59_14392_1	1123234.AUKI01000019_gene466	2.22e-50	179.0	COG0531@1|root,COG0531@2|Bacteria,4NDU2@976|Bacteroidetes,1I02U@117743|Flavobacteriia	976|Bacteroidetes	E	amino acid	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
k59_36817_1	335543.Sfum_1225	4.54e-99	320.0	COG0587@1|root,COG0587@2|Bacteria,1MUIF@1224|Proteobacteria,42MGP@68525|delta/epsilon subdivisions,2WIZ2@28221|Deltaproteobacteria,2MQUW@213462|Syntrophobacterales	28221|Deltaproteobacteria	L	DNA polymerase III alpha subunit	dnaE	-	2.7.7.7	ko:K02337,ko:K14162	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
k59_225958_1	1167006.UWK_01256	1.93e-102	329.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2WJ8D@28221|Deltaproteobacteria,2MHXW@213118|Desulfobacterales	28221|Deltaproteobacteria	V	AcrB/AcrD/AcrF family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_135628_2	717231.Flexsi_0145	1.44e-18	78.2	COG1141@1|root,COG1141@2|Bacteria	2|Bacteria	C	electron transfer activity	-	-	-	ko:K05337	-	-	-	-	ko00000	-	-	-	Fer4_13
k59_28477_1	335543.Sfum_0098	6.96e-111	342.0	COG0466@1|root,COG0466@2|Bacteria,1MUV2@1224|Proteobacteria,42M9W@68525|delta/epsilon subdivisions,2WJ29@28221|Deltaproteobacteria,2MQZP@213462|Syntrophobacterales	28221|Deltaproteobacteria	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon-2	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
k59_149755_1	187272.Mlg_1359	3.12e-20	90.5	COG0114@1|root,COG0114@2|Bacteria,1MUQI@1224|Proteobacteria,1RNUS@1236|Gammaproteobacteria,1WWB4@135613|Chromatiales	135613|Chromatiales	C	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate	fumC	-	4.2.1.2	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	M00009,M00011,M00173,M00376	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	FumaraseC_C,Lyase_1
k59_143101_1	1121405.dsmv_0131	9.89e-76	242.0	COG0107@1|root,COG0118@1|root,COG0107@2|Bacteria,COG0118@2|Bacteria,1MUS0@1224|Proteobacteria,42M44@68525|delta/epsilon subdivisions,2WJFW@28221|Deltaproteobacteria,2MIFH@213118|Desulfobacterales	28221|Deltaproteobacteria	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit	hisF	-	-	ko:K01663,ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase,His_biosynth
k59_218404_1	1121405.dsmv_3299	1.85e-101	303.0	COG0709@1|root,COG0709@2|Bacteria,1MWFG@1224|Proteobacteria,42MC3@68525|delta/epsilon subdivisions,2WK3M@28221|Deltaproteobacteria,2MIG0@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Synthesizes selenophosphate from selenide and ATP	selD	-	2.7.9.3	ko:K01008	ko00450,ko01100,map00450,map01100	-	R03595	RC00002,RC02878	ko00000,ko00001,ko01000,ko03016	-	-	-	AIRS,AIRS_C
k59_51410_2	690850.Desaf_2378	1.69e-25	102.0	COG0765@1|root,COG0765@2|Bacteria,1R4RU@1224|Proteobacteria,42PW7@68525|delta/epsilon subdivisions,2WK9J@28221|Deltaproteobacteria,2M8W2@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	polar amino acid ABC transporter, inner membrane subunit	-	-	-	ko:K02029	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	BPD_transp_1
k59_234261_1	990285.RGCCGE502_00200	4.99e-10	62.4	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2TQPG@28211|Alphaproteobacteria,4B8MB@82115|Rhizobiaceae	28211|Alphaproteobacteria	T	Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains	dctD	-	-	ko:K10126	ko02020,map02020	M00504	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
k59_28489_1	439235.Dalk_3467	1.04e-79	263.0	COG0178@1|root,COG0178@2|Bacteria,1MW0W@1224|Proteobacteria,42M4I@68525|delta/epsilon subdivisions,2WJHM@28221|Deltaproteobacteria,2MI09@213118|Desulfobacterales	28221|Deltaproteobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
k59_173097_1	589865.DaAHT2_0507	1.42e-68	223.0	COG0008@1|root,COG1384@1|root,COG0008@2|Bacteria,COG1384@2|Bacteria,1MUCR@1224|Proteobacteria,42MAI@68525|delta/epsilon subdivisions,2WJ8M@28221|Deltaproteobacteria,2MHXE@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
k59_28493_1	383372.Rcas_3100	1.95e-06	53.9	COG1216@1|root,COG1216@2|Bacteria,2G76E@200795|Chloroflexi,377ZP@32061|Chloroflexia	32061|Chloroflexia	S	PFAM glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
k59_195261_1	82654.Pse7367_1750	2.41e-62	209.0	COG1619@1|root,COG1619@2|Bacteria,1G059@1117|Cyanobacteria,1H7XC@1150|Oscillatoriales	1117|Cyanobacteria	V	microcin C7 resistance	-	-	3.4.17.13	ko:K01297	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_S66
k59_158062_1	1121403.AUCV01000013_gene4008	2.04e-11	66.6	COG5492@1|root,COG5492@2|Bacteria,1QY8X@1224|Proteobacteria,43CAR@68525|delta/epsilon subdivisions,2X7M8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_158062_2	371731.Rsw2DRAFT_1277	1.46e-11	65.9	COG3658@1|root,COG3658@2|Bacteria,1RIG7@1224|Proteobacteria,2U3PI@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	cytochrome	-	-	-	-	-	-	-	-	-	-	-	-	Ni_hydr_CYTB
k59_112635_1	644283.Micau_5332	2.9e-17	85.9	COG0312@1|root,COG0312@2|Bacteria,2GZPS@201174|Actinobacteria,4D8XK@85008|Micromonosporales	201174|Actinobacteria	S	peptidase U62, modulator of DNA gyrase	-	-	-	-	-	-	-	-	-	-	-	-	PmbA_TldD
k59_14407_1	485913.Krac_2474	8.68e-95	288.0	COG3328@1|root,COG3328@2|Bacteria,2G6SX@200795|Chloroflexi	200795|Chloroflexi	L	PFAM transposase mutator type	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_mut
k59_119691_1	1232437.KL661971_gene4894	1.38e-28	111.0	COG2423@1|root,COG2423@2|Bacteria,1MWH6@1224|Proteobacteria,42SUF@68525|delta/epsilon subdivisions,2WPJU@28221|Deltaproteobacteria,2MKU8@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Ornithine cyclodeaminase/mu-crystallin family	-	-	1.4.1.1,4.3.1.12	ko:K01750,ko:K19244	ko00250,ko00330,ko00430,ko01100,ko01110,ko01130,ko01230,map00250,map00330,map00430,map01100,map01110,map01130,map01230	-	R00396,R00671	RC00008,RC00354	ko00000,ko00001,ko01000	-	-	-	OCD_Mu_crystall
k59_119691_2	999541.bgla_2g24710	4.08e-09	57.8	COG0665@1|root,COG0665@2|Bacteria,1MXD1@1224|Proteobacteria,2VKJ5@28216|Betaproteobacteria,1K0VS@119060|Burkholderiaceae	28216|Betaproteobacteria	E	fad dependent oxidoreductase	-	-	1.4.99.6	ko:K19746	ko00472,ko01100,map00472,map01100	-	R11018	RC00006	ko00000,ko00001,ko01000	-	-	-	DAO
k59_36865_1	689781.AUJX01000028_gene1710	3.49e-23	100.0	COG0741@1|root,COG0741@2|Bacteria,1V6DD@1239|Firmicutes,24JDA@186801|Clostridia,2PR11@265975|Oribacterium	186801|Clostridia	M	Transglycosylase SLT domain	yjbJ	-	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	SLT
k59_97260_1	1121875.KB907556_gene617	6.98e-143	413.0	COG3039@1|root,COG3039@2|Bacteria,4NGW9@976|Bacteroidetes,1HZ0D@117743|Flavobacteriia	976|Bacteroidetes	L	PFAM Transposase domain (DUF772)	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_2,DUF772
k59_66582_1	596151.DesfrDRAFT_3125	1.1e-84	262.0	COG4671@1|root,COG4671@2|Bacteria,1N1PQ@1224|Proteobacteria,42MDW@68525|delta/epsilon subdivisions,2WKQK@28221|Deltaproteobacteria,2M92X@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	PFAM Glycosyltransferase 28	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tran_28_C
k59_105124_1	439235.Dalk_2282	2.23e-63	214.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42NFY@68525|delta/epsilon subdivisions,2WKC0@28221|Deltaproteobacteria,2MI11@213118|Desulfobacterales	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	2.7.13.3	ko:K10819	-	-	-	-	ko00000,ko01000	-	-	-	HATPase_c,HisKA,PAS_8,PAS_9,sCache_3_2
k59_105124_2	439235.Dalk_2281	0.000741	41.2	COG0374@1|root,COG0374@2|Bacteria,1MWFJ@1224|Proteobacteria,42Z00@68525|delta/epsilon subdivisions,2WTI9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Nickel-dependent hydrogenase	-	-	1.12.99.6	ko:K06281	ko00633,ko01120,map00633,map01120	-	R08034	RC00250	ko00000,ko00001,ko01000	-	-	-	NiFeSe_Hases
k59_173117_1	96561.Dole_2597	1.12e-44	155.0	COG1082@1|root,COG1082@2|Bacteria,1RB9A@1224|Proteobacteria,42QVE@68525|delta/epsilon subdivisions,2WMSP@28221|Deltaproteobacteria,2MJQN@213118|Desulfobacterales	28221|Deltaproteobacteria	G	PFAM Xylose	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
k59_51438_1	933801.Ahos_0663	4.71e-41	143.0	COG0522@1|root,arCOG04239@2157|Archaea,2XQCT@28889|Crenarchaeota	28889|Crenarchaeota	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rps4	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
k59_241073_1	1279038.KB907338_gene865	6.75e-67	220.0	COG0581@1|root,COG0581@2|Bacteria,1MUWB@1224|Proteobacteria,2TQYQ@28211|Alphaproteobacteria,2JQA8@204441|Rhodospirillales	204441|Rhodospirillales	P	Phosphate transport system permease	pstA	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1,DUF3333
k59_97261_1	102125.Xen7305DRAFT_00039550	8.88e-54	178.0	COG0385@1|root,COG0385@2|Bacteria,1GJMG@1117|Cyanobacteria,3VNEQ@52604|Pleurocapsales	1117|Cyanobacteria	S	PFAM Sodium Bile acid symporter family	-	-	-	ko:K03453	-	-	-	-	ko00000	2.A.28	-	-	SBF
k59_97261_2	1312959.KI914641_gene1300	1.1e-10	58.5	COG4828@1|root,COG4828@2|Bacteria,2IQJ3@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF1622)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1622
k59_158092_1	1094980.Mpsy_0926	1.21e-18	90.1	COG5016@1|root,arCOG02095@2157|Archaea,2XV3W@28890|Euryarchaeota,2N90X@224756|Methanomicrobia	224756|Methanomicrobia	C	TIGRFAM oxaloacetate decarboxylase alpha subunit	pycB	-	6.4.1.1	ko:K01960	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	M00173,M00620	R00344	RC00040,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	iAF692.Mbar_A1586	Biotin_lipoyl,HMGL-like,PYC_OADA
k59_119697_1	639282.DEFDS_1268	1.1e-97	292.0	COG0489@1|root,COG0489@2|Bacteria,2GEUR@200930|Deferribacteres	200930|Deferribacteres	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	-	-	-	-	-	-	-	-	-	-	-	-	ParA
k59_218447_1	1121405.dsmv_1442	3.15e-74	248.0	COG0587@1|root,COG0587@2|Bacteria,1MUIF@1224|Proteobacteria,42MGP@68525|delta/epsilon subdivisions,2WIZ2@28221|Deltaproteobacteria,2MI79@213118|Desulfobacterales	28221|Deltaproteobacteria	L	DNA polymerase III alpha subunit	dnaE	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
k59_143142_1	96561.Dole_2289	2.93e-49	173.0	COG2414@1|root,COG2414@2|Bacteria,1MWBB@1224|Proteobacteria,42NR7@68525|delta/epsilon subdivisions,2WK49@28221|Deltaproteobacteria,2MHYC@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Aldehyde ferredoxin oxidoreductase	-	-	1.2.7.5	ko:K03738	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00309	R08571	RC00242	ko00000,ko00001,ko00002,ko01000	-	-	-	AFOR_C,AFOR_N
k59_211391_1	589865.DaAHT2_1360	9.67e-67	221.0	COG1085@1|root,COG1085@2|Bacteria,1R6SM@1224|Proteobacteria,42QFF@68525|delta/epsilon subdivisions,2WKFN@28221|Deltaproteobacteria,2MIE7@213118|Desulfobacterales	28221|Deltaproteobacteria	C	galactose-1-phosphate uridylyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_173121_1	1123399.AQVE01000045_gene3190	2.1e-24	104.0	COG1783@1|root,COG1783@2|Bacteria,1R66A@1224|Proteobacteria,1RQFD@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Phage terminase, large subunit	Z012_12305	-	-	ko:K06909	-	-	-	-	ko00000	-	-	-	Terminase_3,Terminase_3C
k59_218450_2	56110.Oscil6304_5620	0.000969	43.5	COG0642@1|root,COG5002@1|root,COG0642@2|Bacteria,COG2205@2|Bacteria,COG5002@2|Bacteria,1G09B@1117|Cyanobacteria,1H82F@1150|Oscillatoriales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_9,Response_reg
k59_218451_1	1167006.UWK_02393	1.62e-82	263.0	COG1624@1|root,COG4856@1|root,COG1624@2|Bacteria,COG4856@2|Bacteria,1PEQT@1224|Proteobacteria,42P5A@68525|delta/epsilon subdivisions,2WKPP@28221|Deltaproteobacteria,2MIQR@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria	dacA	-	-	-	-	-	-	-	-	-	-	-	DisA_N,YbbR
k59_180301_1	987059.RBXJA2T_12477	3.42e-61	202.0	COG0483@1|root,COG0483@2|Bacteria,1MUQT@1224|Proteobacteria,2VIXG@28216|Betaproteobacteria,1KJ4K@119065|unclassified Burkholderiales	28216|Betaproteobacteria	G	Inositol monophosphatase	suhB	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
k59_218455_1	644282.Deba_2001	1.69e-89	287.0	COG0525@1|root,COG0525@2|Bacteria,1MV7B@1224|Proteobacteria,42MPZ@68525|delta/epsilon subdivisions,2WIR9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
k59_67113_4	1089439.KB902273_gene2252	9.73e-07	51.2	COG1215@1|root,COG1215@2|Bacteria,1R8C3@1224|Proteobacteria,1RYY8@1236|Gammaproteobacteria,4621Z@72273|Thiotrichales	72273|Thiotrichales	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_173646_2	1121861.KB899915_gene1793	7.88e-23	102.0	COG0210@1|root,COG1379@1|root,COG0210@2|Bacteria,COG1379@2|Bacteria,1MU0G@1224|Proteobacteria,2TS2B@28211|Alphaproteobacteria,2JQP5@204441|Rhodospirillales	204441|Rhodospirillales	L	DNA helicase	-	-	-	-	-	-	-	-	-	-	-	-	UvrD-helicase,UvrD_C
k59_75013_2	335543.Sfum_2548	3.15e-81	247.0	COG1225@1|root,COG1225@2|Bacteria,1N9JS@1224|Proteobacteria,42R82@68525|delta/epsilon subdivisions,2WMVA@28221|Deltaproteobacteria,2MRME@213462|Syntrophobacterales	28221|Deltaproteobacteria	O	Redoxin	-	-	1.11.1.15	ko:K03386	ko04214,map04214	-	-	-	ko00000,ko00001,ko01000,ko04147	-	-	-	AhpC-TSA
k59_173654_1	335543.Sfum_0154	5.74e-73	238.0	COG0073@1|root,COG0143@1|root,COG0073@2|Bacteria,COG0143@2|Bacteria,1MUBY@1224|Proteobacteria,42N1K@68525|delta/epsilon subdivisions,2WIT6@28221|Deltaproteobacteria,2MQAG@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	-	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g,tRNA_bind
k59_75015_1	1380390.JIAT01000010_gene3399	1.12e-05	46.6	COG0411@1|root,COG0411@2|Bacteria,2GMEE@201174|Actinobacteria	201174|Actinobacteria	E	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,BCA_ABC_TP_C
k59_75015_2	439235.Dalk_3799	3.92e-53	176.0	COG0410@1|root,COG0410@2|Bacteria,1MVVC@1224|Proteobacteria,42N2W@68525|delta/epsilon subdivisions,2WJRB@28221|Deltaproteobacteria,2MJD8@213118|Desulfobacterales	28221|Deltaproteobacteria	E	ABC transporter	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
k59_120343_1	335543.Sfum_2572	8.55e-91	271.0	COG0225@1|root,COG0225@2|Bacteria,1R33Z@1224|Proteobacteria,42RS2@68525|delta/epsilon subdivisions,2X9GK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	-	1.8.4.11	ko:K07304	-	-	-	-	ko00000,ko01000	-	-	-	PMSR
k59_234766_1	1121405.dsmv_3288	3.04e-38	132.0	COG0724@1|root,COG0724@2|Bacteria,1N6VR@1224|Proteobacteria,42UQP@68525|delta/epsilon subdivisions,2WQKU@28221|Deltaproteobacteria,2MMAC@213118|Desulfobacterales	28221|Deltaproteobacteria	S	RNA recognition motif	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
k59_234766_2	1232437.KL662042_gene2028	7.68e-21	86.7	COG0328@1|root,COG0328@2|Bacteria,1RI5K@1224|Proteobacteria,42T01@68525|delta/epsilon subdivisions,2WPRB@28221|Deltaproteobacteria,2MNEJ@213118|Desulfobacterales	28221|Deltaproteobacteria	L	RNase H	-	-	-	-	-	-	-	-	-	-	-	-	RNase_H
k59_51999_1	1541960.KQ78_01293	3.51e-86	275.0	COG3299@1|root,COG3497@1|root,COG3299@2|Bacteria,COG3497@2|Bacteria	2|Bacteria	S	Phage tail sheath protein subtilisin-like domain	-	-	3.2.1.78	ko:K01218,ko:K06907	ko00051,ko02024,map00051,map02024	-	R01332	RC00467	ko00000,ko00001,ko01000	-	GH26	-	Baseplate_J,PA14,Phage_sheath_1,Phage_sheath_1C,fn3
k59_79449_2	868595.Desca_0101	6.43e-44	162.0	COG1694@1|root,COG3956@2|Bacteria,1TPK1@1239|Firmicutes,247XM@186801|Clostridia,2613S@186807|Peptococcaceae	186801|Clostridia	S	TIGRFAM MazG family protein	mazG	-	3.6.1.66	ko:K02428,ko:K02499	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000,ko03036	-	-	-	MazG,TP_methylase
k59_11243_1	335543.Sfum_0004	5.52e-22	97.4	COG5345@1|root,COG5345@2|Bacteria,1MWVH@1224|Proteobacteria,42NJB@68525|delta/epsilon subdivisions,2WM62@28221|Deltaproteobacteria,2MS28@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Uncharacterized protein conserved in bacteria (DUF2333)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2333
k59_79451_2	1121396.KB893077_gene738	2.18e-68	226.0	COG0438@1|root,COG0438@2|Bacteria,1R3Q9@1224|Proteobacteria,42MQ2@68525|delta/epsilon subdivisions,2WM1F@28221|Deltaproteobacteria,2MQ1W@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Glycosyl transferases group 1	-	-	2.4.1.345	ko:K08256	-	-	R11702	-	ko00000,ko01000,ko01003	-	GT4	-	Glyco_transf_4,Glycos_transf_1
k59_200625_1	1379281.AVAG01000011_gene1290	7.91e-27	113.0	COG0860@1|root,COG1729@1|root,COG0860@2|Bacteria,COG1729@2|Bacteria,1MUQK@1224|Proteobacteria,42MPH@68525|delta/epsilon subdivisions,2WJHW@28221|Deltaproteobacteria,2M7QR@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	PFAM cell wall hydrolase autolysin	amiC	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	AMIN,Amidase_3,TPR_6
k59_94447_1	706587.Desti_2454	3.62e-143	416.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,42MK5@68525|delta/epsilon subdivisions,2WJ3Z@28221|Deltaproteobacteria,2MQ86@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	PFAM Acyl-CoA dehydrogenase	-	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016491,GO:0016627,GO:0022607,GO:0036094,GO:0043167,GO:0043168,GO:0043933,GO:0044085,GO:0048037,GO:0050660,GO:0050662,GO:0051259,GO:0051262,GO:0052890,GO:0055114,GO:0065003,GO:0071840,GO:0097159,GO:1901265,GO:1901363	1.3.8.10,1.3.8.11	ko:K19066,ko:K19067	ko00362,ko01120,map00362,map01120	-	R09252,R10601	RC00248,RC02035	ko00000,ko00001,ko01000	-	-	iAF987.Gmet_3306	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
k59_18423_1	1121085.AUCI01000017_gene2527	2.96e-49	159.0	COG0662@1|root,COG0662@2|Bacteria,1V7K2@1239|Firmicutes,4HJNP@91061|Bacilli,1ZHWZ@1386|Bacillus	91061|Bacilli	G	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
k59_185852_1	1026970.XP_008824872.1	1.22e-57	196.0	COG2036@1|root,COG5262@1|root,KOG1745@2759|Eukaryota,KOG1756@2759|Eukaryota,KOG3467@2759|Eukaryota,39ZTV@33154|Opisthokonta,3BPDH@33208|Metazoa,3D6BK@33213|Bilateria,48E1W@7711|Chordata,49B7M@7742|Vertebrata,3JEM2@40674|Mammalia,35PS8@314146|Euarchontoglires	33208|Metazoa	B	Histone cluster 1	HIST1H3D	GO:0000228,GO:0000785,GO:0000786,GO:0000788,GO:0000790,GO:0003674,GO:0003676,GO:0003677,GO:0003682,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005694,GO:0006323,GO:0006325,GO:0006333,GO:0006334,GO:0006335,GO:0006996,GO:0008150,GO:0009987,GO:0010468,GO:0016043,GO:0019222,GO:0022607,GO:0031490,GO:0031491,GO:0031492,GO:0031497,GO:0031974,GO:0031981,GO:0032991,GO:0032993,GO:0034622,GO:0034723,GO:0034728,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043933,GO:0044085,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044446,GO:0044454,GO:0044464,GO:0044815,GO:0044877,GO:0050789,GO:0050794,GO:0051259,GO:0051262,GO:0051276,GO:0051290,GO:0051291,GO:0060255,GO:0060968,GO:0065003,GO:0065004,GO:0065007,GO:0070013,GO:0071103,GO:0071824,GO:0071840,GO:0097159,GO:1901363	-	ko:K11253,ko:K11254	ko05034,ko05202,ko05203,ko05322,map05034,map05202,map05203,map05322	-	-	-	ko00000,ko00001,ko03036,ko04147	-	-	-	CENP-T_C,Histone,Histone_H2A_C
k59_185852_3	12957.ACEP26606-PA	5.32e-45	149.0	KOG1744@1|root,KOG1744@2759|Eukaryota,3A1HW@33154|Opisthokonta,3BQEI@33208|Metazoa,3D7NQ@33213|Bilateria,41ZBP@6656|Arthropoda,3SQBI@50557|Insecta,46IDR@7399|Hymenoptera	33208|Metazoa	B	Histone H2B	-	GO:0000228,GO:0000785,GO:0000786,GO:0000788,GO:0000790,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005694,GO:0006323,GO:0006325,GO:0006333,GO:0006334,GO:0006996,GO:0008150,GO:0009987,GO:0016043,GO:0022607,GO:0031497,GO:0031974,GO:0031981,GO:0032991,GO:0032993,GO:0034622,GO:0034728,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043933,GO:0044085,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044446,GO:0044454,GO:0044464,GO:0044815,GO:0051276,GO:0065003,GO:0065004,GO:0070013,GO:0071103,GO:0071824,GO:0071840,GO:0097159,GO:1901363	-	ko:K11252,ko:K11275	ko05034,ko05203,ko05322,map05034,map05203,map05322	-	-	-	ko00000,ko00001,ko03036,ko04147	-	-	-	Histone
k59_170241_1	439235.Dalk_2649	6.55e-151	434.0	COG1104@1|root,COG1104@2|Bacteria,1MU1C@1224|Proteobacteria,42M5V@68525|delta/epsilon subdivisions,2WIR6@28221|Deltaproteobacteria,2MHW4@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine	nifS-1	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
k59_33856_1	439235.Dalk_1820	1.3e-56	193.0	28I8B@1|root,2Z8B5@2|Bacteria,1MUNM@1224|Proteobacteria,42NZH@68525|delta/epsilon subdivisions,2WKHB@28221|Deltaproteobacteria,2MISZ@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM Cytochrome c, bacterial	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_CIII,Cytochrome_C554,Cytochrome_cB
k59_102273_1	395019.Bmul_5727	9.96e-39	142.0	COG3335@1|root,COG3335@2|Bacteria,1MW7X@1224|Proteobacteria,2VMDX@28216|Betaproteobacteria,1K2WH@119060|Burkholderiaceae	28216|Betaproteobacteria	L	Elements of external origin	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,HTH_32
k59_231116_2	56780.SYN_00994	2.5e-40	148.0	COG0018@1|root,COG0018@2|Bacteria,1MU4J@1224|Proteobacteria,42MTY@68525|delta/epsilon subdivisions,2WKII@28221|Deltaproteobacteria,2MQ9N@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	TIGRFAM Arginyl-tRNA synthetase	argS	GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	iAF987.Gmet_1434	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
k59_86671_1	933262.AXAM01000040_gene1222	8.39e-37	134.0	COG4123@1|root,COG4123@2|Bacteria,1MXEQ@1224|Proteobacteria,42SAA@68525|delta/epsilon subdivisions,2WPCM@28221|Deltaproteobacteria,2MJTD@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Methyltransferase small domain	-	-	2.1.1.223	ko:K15460	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	MTS,Methyltransf_31
k59_86671_2	335543.Sfum_0110	2.52e-21	94.4	COG4198@1|root,COG4198@2|Bacteria,1NPPY@1224|Proteobacteria,42NTB@68525|delta/epsilon subdivisions,2WKNX@28221|Deltaproteobacteria,2MQH0@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF1015)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1015
k59_132477_1	335543.Sfum_0213	9.96e-226	653.0	COG0550@1|root,COG0550@2|Bacteria,1MUFZ@1224|Proteobacteria,42MM9@68525|delta/epsilon subdivisions,2WJTT@28221|Deltaproteobacteria,2MQTZ@213462|Syntrophobacterales	28221|Deltaproteobacteria	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,zf-C4_Topoisom
k59_155341_1	1121935.AQXX01000126_gene903	3.74e-35	132.0	COG0726@1|root,COG0726@2|Bacteria,1MVKH@1224|Proteobacteria,1RZ5C@1236|Gammaproteobacteria,1XMR2@135619|Oceanospirillales	135619|Oceanospirillales	G	Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
k59_102275_1	1304885.AUEY01000036_gene2247	6.59e-86	270.0	COG0591@1|root,COG0591@2|Bacteria,1PNHU@1224|Proteobacteria,43AQ2@68525|delta/epsilon subdivisions,2X63U@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Sodium:solute symporter family	-	-	-	-	-	-	-	-	-	-	-	-	SSF
k59_26009_1	177437.HRM2_03300	9.34e-12	65.5	COG0296@1|root,COG0296@2|Bacteria,1NIZI@1224|Proteobacteria,42WYM@68525|delta/epsilon subdivisions,2WSNX@28221|Deltaproteobacteria,2MMER@213118|Desulfobacterales	28221|Deltaproteobacteria	G	Glycogen recognition site of AMP-activated protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	AMPK1_CBM
k59_200633_1	1370122.JHXQ01000012_gene3519	1.67e-05	51.2	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,2TS6B@28211|Alphaproteobacteria,4B8QD@82115|Rhizobiaceae	28211|Alphaproteobacteria	M	Belongs to the peptidase S1C family	htrA2	GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006457,GO:0006508,GO:0006515,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0009056,GO:0009057,GO:0009266,GO:0009408,GO:0009628,GO:0009897,GO:0009986,GO:0009987,GO:0016020,GO:0016021,GO:0016787,GO:0017171,GO:0019538,GO:0030163,GO:0030288,GO:0030313,GO:0031224,GO:0031226,GO:0031233,GO:0031975,GO:0042597,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051603,GO:0061077,GO:0070011,GO:0071575,GO:0071704,GO:0071944,GO:0098552,GO:0140096,GO:1901564,GO:1901565,GO:1901575	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
k59_200633_2	305700.B447_07137	1.52e-72	235.0	COG2211@1|root,COG2211@2|Bacteria,1MWSH@1224|Proteobacteria,2VJEQ@28216|Betaproteobacteria,2KUQ3@206389|Rhodocyclales	206389|Rhodocyclales	G	BT1 family	-	-	-	-	-	-	-	-	-	-	-	-	BT1
k59_71695_2	933262.AXAM01000054_gene2670	4.26e-62	195.0	COG0494@1|root,COG0494@2|Bacteria,1Q0FU@1224|Proteobacteria,42S2C@68525|delta/epsilon subdivisions,2WNP0@28221|Deltaproteobacteria,2MJSY@213118|Desulfobacterales	28221|Deltaproteobacteria	L	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
k59_170257_1	378806.STAUR_3195	2.37e-22	101.0	COG1450@1|root,COG1450@2|Bacteria,1MUUA@1224|Proteobacteria,42M9I@68525|delta/epsilon subdivisions,2WK1H@28221|Deltaproteobacteria,2YUDZ@29|Myxococcales	28221|Deltaproteobacteria	NU	Type II and III secretion system protein	gspD	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	Secretin,Secretin_N
k59_64140_2	335543.Sfum_1385	6.96e-52	168.0	2DUTK@1|root,32UXS@2|Bacteria,1N1IZ@1224|Proteobacteria,42TJU@68525|delta/epsilon subdivisions,2WQQ7@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_223366_1	1121468.AUBR01000123_gene1674	7.87e-11	65.1	COG2201@1|root,COG2201@2|Bacteria,1V3IU@1239|Firmicutes,24HJF@186801|Clostridia,42GI7@68295|Thermoanaerobacterales	186801|Clostridia	T	PFAM response regulator receiver	-	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
k59_125125_1	1121456.ATVA01000012_gene2676	6.56e-28	114.0	COG2304@1|root,COG2885@1|root,COG2304@2|Bacteria,COG2885@2|Bacteria,1R7WJ@1224|Proteobacteria,42QJK@68525|delta/epsilon subdivisions,2WJX0@28221|Deltaproteobacteria,2M7W6@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Belongs to the ompA family	-	-	-	ko:K03286	-	-	-	-	ko00000,ko02000	1.B.6	-	-	OmpA,TSP_3,VWA,VWA_2
k59_140149_1	706587.Desti_1835	7.64e-101	309.0	COG0146@1|root,COG0146@2|Bacteria,1QU46@1224|Proteobacteria,43CGH@68525|delta/epsilon subdivisions,2WJ3J@28221|Deltaproteobacteria,2MS4N@213462|Syntrophobacterales	28221|Deltaproteobacteria	EQ	Hydantoinase B/oxoprolinase	hyuB	-	3.5.2.14	ko:K01474	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydantoinase_B
k59_231130_1	1161902.HMPREF0378_1504	3.11e-37	142.0	COG0493@1|root,COG3383@1|root,COG0493@2|Bacteria,COG3383@2|Bacteria,1TQ1A@1239|Firmicutes,248EK@186801|Clostridia,3WCXB@538999|Clostridiales incertae sedis	186801|Clostridia	C	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster	-	-	1.17.1.9,1.3.1.1	ko:K00123,ko:K17722	ko00240,ko00410,ko00630,ko00680,ko00770,ko01100,ko01120,ko01200,map00240,map00410,map00630,map00680,map00770,map01100,map01120,map01200	M00046	R00519,R00977,R01414,R11026	RC00072,RC00123,RC02796	ko00000,ko00001,ko00002,ko01000	-	-	-	Fe_hyd_SSU,Fe_hyd_lg_C,Fer2_4,Fer4,Fer4_20,Fer4_9,Molybdop_Fe4S4,Molybdopterin,Pyr_redox_2,Pyr_redox_3
k59_116900_1	649639.Bcell_0781	1.17e-42	156.0	COG3616@1|root,COG3616@2|Bacteria,1TSES@1239|Firmicutes,4HA93@91061|Bacilli,1ZQJR@1386|Bacillus	91061|Bacilli	E	Putative serine dehydratase domain	-	-	-	-	-	-	-	-	-	-	-	-	Ala_racemase_N,D-ser_dehydrat
k59_177679_1	706587.Desti_3892	2.47e-52	177.0	COG0509@1|root,COG0509@2|Bacteria,1RC80@1224|Proteobacteria,42R79@68525|delta/epsilon subdivisions,2WN04@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Glycine cleavage H-protein	-	-	-	-	-	-	-	-	-	-	-	-	GCV_H
k59_11276_1	1121451.DESAM_22094	4.47e-12	69.3	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42MXI@68525|delta/epsilon subdivisions,2X222@28221|Deltaproteobacteria,2M8BY@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal,PAS_4,dCache_1
k59_48845_1	926550.CLDAP_02040	2.19e-183	522.0	COG3385@1|root,COG3385@2|Bacteria,2G7UE@200795|Chloroflexi	200795|Chloroflexi	L	transposase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_200651_1	1242864.D187_007111	4.64e-45	154.0	COG0854@1|root,COG0854@2|Bacteria,1MU9W@1224|Proteobacteria,42NZY@68525|delta/epsilon subdivisions,2WJDY@28221|Deltaproteobacteria,2YVHT@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate	pdxJ	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	2.6.99.2	ko:K03474	ko00750,ko01100,map00750,map01100	M00124	R05838	RC01476	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1885	PdxJ
k59_231135_1	247490.KSU1_C1306	1.32e-71	237.0	COG1449@1|root,COG1449@2|Bacteria,2IYKX@203682|Planctomycetes	203682|Planctomycetes	G	Belongs to the glycosyl hydrolase 57 family	-	-	-	-	-	-	-	-	-	-	-	-	DUF3536,Glyco_hydro_57
k59_11279_1	335543.Sfum_0488	5.81e-93	281.0	COG0429@1|root,COG0429@2|Bacteria,1MWV1@1224|Proteobacteria,42N26@68525|delta/epsilon subdivisions,2WK9Q@28221|Deltaproteobacteria,2MR40@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Alpha/beta hydrolase family	-	-	-	ko:K07019	-	-	-	-	ko00000	-	-	-	Abhydrolase_1,Hydrolase_4
k59_155353_1	1121405.dsmv_2651	2.16e-82	262.0	COG5421@1|root,COG5421@2|Bacteria,1R3NX@1224|Proteobacteria,42QDV@68525|delta/epsilon subdivisions,2WIRQ@28221|Deltaproteobacteria,2MN1S@213118|Desulfobacterales	68525|delta/epsilon subdivisions	L	PFAM transposase IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
k59_185883_1	1150621.SMUL_1208	3.24e-13	73.2	COG0119@1|root,COG0119@2|Bacteria,1MUNQ@1224|Proteobacteria,42MSP@68525|delta/epsilon subdivisions,2YNBC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Belongs to the alpha-IPM synthase homocitrate synthase family	-	-	2.3.3.14	ko:K02594	ko00620,map00620	-	R00271	RC00004,RC00067,RC02754	ko00000,ko00001,ko01000	-	-	-	HMGL-like
k59_48852_1	502025.Hoch_5214	6.35e-14	74.7	COG0206@1|root,COG3170@1|root,COG0206@2|Bacteria,COG3170@2|Bacteria,1MV2X@1224|Proteobacteria,42MHK@68525|delta/epsilon subdivisions,2WJAZ@28221|Deltaproteobacteria,2YTTW@29|Myxococcales	28221|Deltaproteobacteria	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
k59_56774_1	7668.SPU_009575-tr	1.6e-79	266.0	COG2801@1|root,KOG0017@2759|Eukaryota,39Z2B@33154|Opisthokonta,3BIIP@33208|Metazoa,3D489@33213|Bilateria	33208|Metazoa	L	SCAN domain	-	-	-	-	-	-	-	-	-	-	-	-	RVT_1,SCAN,rve
k59_64147_1	555779.Dthio_PD3706	2.29e-42	140.0	COG3436@1|root,COG3436@2|Bacteria,1N638@1224|Proteobacteria,430NK@68525|delta/epsilon subdivisions,2WVZ0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	PFAM IS66 Orf2 family protein	-	-	-	ko:K07484	-	-	-	-	ko00000	-	-	-	TnpB_IS66
k59_208488_2	96561.Dole_2251	1.19e-51	176.0	COG0437@1|root,COG0437@2|Bacteria,1MU1B@1224|Proteobacteria,42M97@68525|delta/epsilon subdivisions,2WJB4@28221|Deltaproteobacteria,2MJB7@213118|Desulfobacterales	28221|Deltaproteobacteria	C	4Fe-4S dicluster domain	hmcB	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Fer4_11,Fer4_4,Fer4_7
k59_125134_1	1121430.JMLG01000041_gene2463	4.08e-97	307.0	COG5421@1|root,COG5421@2|Bacteria,1TPAA@1239|Firmicutes,2492T@186801|Clostridia,262BK@186807|Peptococcaceae	186801|Clostridia	L	PFAM Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
k59_140699_2	1121396.KB892925_gene3644	1.19e-21	89.0	COG1359@1|root,COG1359@2|Bacteria,1NGPW@1224|Proteobacteria,42TXG@68525|delta/epsilon subdivisions,2WQI4@28221|Deltaproteobacteria,2MKN6@213118|Desulfobacterales	28221|Deltaproteobacteria	S	PFAM Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	ABM
k59_140699_3	929556.Solca_1877	8.04e-07	50.1	COG0288@1|root,COG0659@1|root,COG0288@2|Bacteria,COG0659@2|Bacteria,4NE9G@976|Bacteroidetes,1INYY@117747|Sphingobacteriia	976|Bacteroidetes	P	COGs COG0659 Sulfate permease and related transporter (MFS superfamily)	sulP	-	4.2.1.1	ko:K01673,ko:K03321	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000,ko02000	2.A.53.3	-	-	Sulfate_transp
k59_125570_1	1121447.JONL01000002_gene1998	7.49e-104	326.0	28HB2@1|root,2Z7N8@2|Bacteria,1P4RV@1224|Proteobacteria,42NVF@68525|delta/epsilon subdivisions,2WKNV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Fatty acid cis/trans isomerase (CTI)	-	-	-	-	-	-	-	-	-	-	-	-	CTI
k59_186422_1	96561.Dole_1460	8.25e-89	263.0	COG0652@1|root,COG0652@2|Bacteria,1R9ZQ@1224|Proteobacteria,42RI1@68525|delta/epsilon subdivisions,2WNBG@28221|Deltaproteobacteria,2MK83@213118|Desulfobacterales	28221|Deltaproteobacteria	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	ppiB	-	5.2.1.8	ko:K03767,ko:K03768	ko01503,ko04217,map01503,map04217	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04147	-	-	-	Pro_isomerase
k59_140701_1	589924.Ferp_1136	2e-37	139.0	COG0087@1|root,arCOG04070@2157|Archaea,2XT9B@28890|Euryarchaeota,245SD@183980|Archaeoglobi	183980|Archaeoglobi	J	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit	rpl3	-	-	ko:K02906	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L3
k59_95040_1	1123371.ATXH01000010_gene735	5.4e-131	383.0	COG0538@1|root,COG0538@2|Bacteria,2GH2J@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	C	Isocitrate/isopropylmalate dehydrogenase	-	-	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
k59_223650_1	269799.Gmet_1687	6.98e-67	218.0	COG0535@1|root,COG0535@2|Bacteria,1Q4F6@1224|Proteobacteria,42Z23@68525|delta/epsilon subdivisions,2WU1H@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Iron-sulfur cluster-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_14,Radical_SAM,SPASM
k59_34511_1	1121405.dsmv_1924	3.36e-48	164.0	COG0620@1|root,COG0620@2|Bacteria,1QB3M@1224|Proteobacteria,42NP4@68525|delta/epsilon subdivisions,2WK9Z@28221|Deltaproteobacteria,2MJ74@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_64451_1	653733.Selin_1858	2.48e-29	121.0	COG1924@1|root,COG3580@1|root,COG1924@2|Bacteria,COG3580@2|Bacteria	2|Bacteria	I	CoA-substrate-specific enzyme activase	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG,DUF2229
k59_72380_1	1121456.ATVA01000011_gene1881	1.02e-66	217.0	COG2403@1|root,COG2403@2|Bacteria,1MV4C@1224|Proteobacteria,42NE0@68525|delta/epsilon subdivisions,2WJ94@28221|Deltaproteobacteria,2M9KE@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	cyclic 2,3-diphosphoglycerate synthetase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_201233_1	1121439.dsat_0673	4.86e-50	167.0	COG2427@1|root,COG2427@2|Bacteria,1P6AT@1224|Proteobacteria,43355@68525|delta/epsilon subdivisions,2WXWE@28221|Deltaproteobacteria,2MBQA@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF1641)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1641
k59_223653_1	316274.Haur_1728	1.11e-07	54.3	COG2909@1|root,COG2909@2|Bacteria,2G7Q4@200795|Chloroflexi,3754G@32061|Chloroflexia	32061|Chloroflexia	K	ATP-dependent transcriptional regulator, MalT-like, LuxR family	-	-	-	ko:K03556	-	-	-	-	ko00000,ko03000	-	-	-	GerE
k59_18920_1	570967.JMLV01000002_gene1806	1.73e-72	227.0	COG0604@1|root,COG0604@2|Bacteria,1MWBD@1224|Proteobacteria,2TS3Z@28211|Alphaproteobacteria,2JQBK@204441|Rhodospirillales	204441|Rhodospirillales	C	COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases	-	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
k59_133139_1	520999.PROVALCAL_00518	1.55e-46	164.0	COG2201@1|root,COG2201@2|Bacteria,1MWCN@1224|Proteobacteria,1RN67@1236|Gammaproteobacteria,3Z8WM@586|Providencia	1236|Gammaproteobacteria	NT	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR	cheB	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006464,GO:0006482,GO:0006807,GO:0006935,GO:0008150,GO:0008152,GO:0008214,GO:0008984,GO:0009605,GO:0009987,GO:0016020,GO:0016787,GO:0016788,GO:0018277,GO:0019538,GO:0019899,GO:0036211,GO:0040011,GO:0042221,GO:0042330,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051723,GO:0052689,GO:0070988,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1990827	3.1.1.61,3.5.1.44	ko:K03412	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,Response_reg
k59_209030_1	1265505.ATUG01000002_gene1896	4.6e-69	223.0	COG2308@1|root,COG2308@2|Bacteria,1NG4H@1224|Proteobacteria,42WK0@68525|delta/epsilon subdivisions,2WS0X@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Evidence 4 Homologs of previously reported genes of	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_11986_1	1265505.ATUG01000002_gene1598	4.41e-54	175.0	COG1309@1|root,COG1309@2|Bacteria,1R6RX@1224|Proteobacteria,42T50@68525|delta/epsilon subdivisions,2WPVV@28221|Deltaproteobacteria,2MK9W@213118|Desulfobacterales	28221|Deltaproteobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	ko:K16137	-	-	-	-	ko00000,ko03000	-	-	-	TetR_C_13,TetR_N
k59_3382_1	675814.VIC_003488	3.69e-13	65.5	COG0607@1|root,COG0607@2|Bacteria,1RHUS@1224|Proteobacteria,1S3ZV@1236|Gammaproteobacteria,1XXFI@135623|Vibrionales	135623|Vibrionales	P	Rhodanese-related sulfurtransferase	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
k59_3382_2	349521.HCH_04055	2.74e-64	206.0	COG4977@1|root,COG4977@2|Bacteria,1MUDK@1224|Proteobacteria,1RP9W@1236|Gammaproteobacteria,1XP5I@135619|Oceanospirillales	135619|Oceanospirillales	K	Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain	-	-	-	ko:K13633	-	-	-	-	ko00000,ko03000	-	-	-	DJ-1_PfpI,HTH_18
k59_186438_1	1121865.OMW_00174	5.25e-13	71.2	COG0675@1|root,COG0675@2|Bacteria,1TRNY@1239|Firmicutes,4HBB6@91061|Bacilli,4B2BQ@81852|Enterococcaceae	91061|Bacilli	L	Putative transposase DNA-binding domain	-	-	-	ko:K07496	-	-	-	-	ko00000	-	-	-	HTH_OrfB_IS605,OrfB_IS605,OrfB_Zn_ribbon
k59_18924_1	1274524.BSONL12_07008	2.54e-50	174.0	COG0471@1|root,COG0471@2|Bacteria,1TSGE@1239|Firmicutes,4HDE4@91061|Bacilli,1ZC2I@1386|Bacillus	91061|Bacilli	P	Sodium:sulfate symporter transmembrane region	yflS	-	-	ko:K03319	-	-	-	-	ko00000	2.A.47	-	-	Na_sulph_symp
k59_18924_2	103690.17131131	2.97e-35	129.0	COG2334@1|root,COG2334@2|Bacteria,1G1QD@1117|Cyanobacteria,1HIXP@1161|Nostocales	1117|Cyanobacteria	S	PFAM Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
k59_201242_1	335543.Sfum_2415	8.42e-130	374.0	COG1127@1|root,COG1127@2|Bacteria,1MUSD@1224|Proteobacteria,42NTG@68525|delta/epsilon subdivisions,2WKHW@28221|Deltaproteobacteria,2MQ9V@213462|Syntrophobacterales	28221|Deltaproteobacteria	Q	ABC-type transport system involved in resistance to organic solvents, ATPase component	-	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
k59_170910_1	525897.Dbac_1964	6.63e-63	206.0	COG2848@1|root,COG2848@2|Bacteria,1NAFG@1224|Proteobacteria,42NH7@68525|delta/epsilon subdivisions,2WJJM@28221|Deltaproteobacteria,2M94X@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	UPF0210 protein	-	-	-	ko:K09157	-	-	-	-	ko00000	-	-	-	DUF711
k59_196014_1	335543.Sfum_0824	2.32e-75	251.0	COG0493@1|root,COG1148@1|root,COG0493@2|Bacteria,COG1148@2|Bacteria,1MU2H@1224|Proteobacteria,42M6X@68525|delta/epsilon subdivisions,2X6YD@28221|Deltaproteobacteria,2MQTQ@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.17.1.10,1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388,ko:K15022	ko00680,ko00720,ko01100,ko01120,ko01200,map00680,map00720,map01100,map01120,map01200	M00356,M00357,M00377,M00563,M00567	R00134,R04540,R11928,R11931,R11943,R11944	RC00011,RC02796	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_20,Pyr_redox_2
k59_234930_1	635013.TherJR_0023	1.39e-37	139.0	COG0502@1|root,COG0502@2|Bacteria,1TPYQ@1239|Firmicutes,248H8@186801|Clostridia,261CE@186807|Peptococcaceae	186801|Clostridia	C	TIGRFAM pyrrolysine biosynthesis radical SAM protein	-	-	5.4.99.58	ko:K16180	ko00300,ko01120,map00300,map01120	-	R10010	RC02995	ko00000,ko00001,ko01000	-	-	-	Radical_SAM
k59_136352_1	876269.ARWA01000001_gene209	2.75e-77	244.0	COG1032@1|root,COG1032@2|Bacteria,1MY2Y@1224|Proteobacteria,2TUIT@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,DUF4070,Radical_SAM
k59_196015_1	335543.Sfum_0062	1.72e-66	213.0	COG0078@1|root,COG0078@2|Bacteria,1MUFM@1224|Proteobacteria,42M0Q@68525|delta/epsilon subdivisions,2WJ3G@28221|Deltaproteobacteria,2MQ5Z@213462|Syntrophobacterales	28221|Deltaproteobacteria	E	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline	argF	GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.1.3.3,2.1.3.9	ko:K00611,ko:K09065	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01398,R07245	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
k59_21915_1	706587.Desti_4160	5e-39	137.0	COG0745@1|root,COG0745@2|Bacteria,1MZPD@1224|Proteobacteria,42U2Y@68525|delta/epsilon subdivisions,2WQ1I@28221|Deltaproteobacteria,2MRWP@213462|Syntrophobacterales	28221|Deltaproteobacteria	KT	Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Usp
k59_90537_1	1304888.ATWF01000001_gene2452	3.02e-56	192.0	COG0367@1|root,COG0367@2|Bacteria	2|Bacteria	E	asparagine synthase	asnB	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_6,GATase_7
k59_150595_2	96561.Dole_0512	3.81e-76	243.0	COG0739@1|root,COG0739@2|Bacteria,1NESH@1224|Proteobacteria,42MGB@68525|delta/epsilon subdivisions,2WJ7F@28221|Deltaproteobacteria,2MI1U@213118|Desulfobacterales	28221|Deltaproteobacteria	M	PFAM peptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
k59_113451_1	1499967.BAYZ01000048_gene2696	2.95e-103	312.0	COG2230@1|root,COG2230@2|Bacteria	2|Bacteria	M	cyclopropane-fatty-acyl-phospholipid synthase	cfa	-	2.1.1.317,2.1.1.79	ko:K00574,ko:K20238	-	-	-	-	ko00000,ko01000	-	-	iJN746.PP_2734	CMAS
k59_120718_1	395494.Galf_2147	4.58e-37	129.0	COG0853@1|root,COG0853@2|Bacteria,1RI1B@1224|Proteobacteria,2VSDU@28216|Betaproteobacteria,44VUZ@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine	panD	-	4.1.1.11	ko:K01579	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R00489	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Asp_decarbox
k59_6075_1	335543.Sfum_3753	4.16e-70	222.0	COG0826@1|root,COG0826@2|Bacteria,1N4QJ@1224|Proteobacteria,42YJR@68525|delta/epsilon subdivisions,2WUQ1@28221|Deltaproteobacteria,2MR6V@213462|Syntrophobacterales	28221|Deltaproteobacteria	O	Peptidase family U32	-	-	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_U32
k59_219099_1	706587.Desti_1206	4.49e-93	286.0	COG0119@1|root,COG0119@2|Bacteria,1MUNQ@1224|Proteobacteria,42MSP@68525|delta/epsilon subdivisions,2WIUZ@28221|Deltaproteobacteria,2MQXU@213462|Syntrophobacterales	28221|Deltaproteobacteria	E	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)	leuA	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
k59_83103_1	497964.CfE428DRAFT_5292	9.49e-34	123.0	COG0745@1|root,COG0745@2|Bacteria,46UQH@74201|Verrucomicrobia	74201|Verrucomicrobia	K	Two component transcriptional regulator, winged helix family	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
k59_21917_1	1121405.dsmv_3759	1.71e-93	281.0	COG1108@1|root,COG1108@2|Bacteria,1MVC2@1224|Proteobacteria,42MYM@68525|delta/epsilon subdivisions,2WJAM@28221|Deltaproteobacteria,2MIQY@213118|Desulfobacterales	28221|Deltaproteobacteria	P	PFAM ABC 3 transport family	-	-	-	ko:K09816,ko:K09819	ko02010,map02010	M00242,M00243	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15,3.A.1.15.3,3.A.1.15.5	-	-	ABC-3
k59_44483_1	1033737.CAEV01000022_gene3295	0.000139	47.8	COG3279@1|root,COG3279@2|Bacteria,1TSDB@1239|Firmicutes,24MQ4@186801|Clostridia,36KUT@31979|Clostridiaceae	186801|Clostridia	KT	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
k59_158753_1	1210884.HG799462_gene8346	1.55e-39	141.0	COG0031@1|root,COG0031@2|Bacteria,2IXCX@203682|Planctomycetes	203682|Planctomycetes	E	cysteine synthase	-	-	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
k59_158753_2	933262.AXAM01000031_gene3006	1.32e-32	122.0	COG1045@1|root,COG1045@2|Bacteria,1MVFX@1224|Proteobacteria,42MND@68525|delta/epsilon subdivisions,2WJC3@28221|Deltaproteobacteria,2MIG5@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Bacterial transferase hexapeptide (six repeats)	cysE	-	2.3.1.30	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	M00021	R00586	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,SATase_N
k59_196022_1	195103.CPF_1963	3.74e-19	84.7	COG0336@1|root,COG0336@2|Bacteria,1TPBV@1239|Firmicutes,247JF@186801|Clostridia,36EJ7@31979|Clostridiaceae	186801|Clostridia	J	Belongs to the RNA methyltransferase TrmD family	trmD	-	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	tRNA_m1G_MT
k59_196022_2	439235.Dalk_4645	5.1e-59	189.0	COG4752@1|root,COG4752@2|Bacteria,1RJ2G@1224|Proteobacteria,42SXX@68525|delta/epsilon subdivisions,2WP1I@28221|Deltaproteobacteria,2MJZA@213118|Desulfobacterales	28221|Deltaproteobacteria	S	SAM-dependent RNA methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltrn_RNA_4
k59_196022_3	1121405.dsmv_2124	1.01e-52	168.0	COG0335@1|root,COG0335@2|Bacteria,1RH3A@1224|Proteobacteria,42TMU@68525|delta/epsilon subdivisions,2WQ67@28221|Deltaproteobacteria,2MK6N@213118|Desulfobacterales	28221|Deltaproteobacteria	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	rplS	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
k59_44486_1	1116232.AHBF01000116_gene4393	1.01e-11	71.6	COG2021@1|root,COG2021@2|Bacteria,2IAQP@201174|Actinobacteria	201174|Actinobacteria	E	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
k59_204337_1	68170.KL590487_gene8931	2.08e-68	219.0	COG5659@1|root,COG5659@2|Bacteria,2GIU9@201174|Actinobacteria,4E1YI@85010|Pseudonocardiales	201174|Actinobacteria	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_5
k59_226746_1	933262.AXAM01000041_gene1901	2.35e-90	270.0	COG0247@1|root,COG0247@2|Bacteria,1R4ZK@1224|Proteobacteria,42NMT@68525|delta/epsilon subdivisions,2WIQV@28221|Deltaproteobacteria,2MJ6N@213118|Desulfobacterales	28221|Deltaproteobacteria	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_8
k59_75182_1	768670.Calni_0382	4.68e-38	139.0	COG1984@1|root,COG1984@2|Bacteria	2|Bacteria	E	allophanate hydrolase subunit 2	kipA	-	6.3.4.6	ko:K01941,ko:K06350	ko00220,ko00791,ko01100,map00220,map00791,map01100	-	R00774	RC00378	ko00000,ko00001,ko01000	-	-	-	CT_A_B,CT_C_D,SLH
k59_128565_1	335543.Sfum_3301	1.04e-102	315.0	COG0119@1|root,COG0119@2|Bacteria,1R8DM@1224|Proteobacteria,42PDN@68525|delta/epsilon subdivisions,2WKIJ@28221|Deltaproteobacteria,2MQ4N@213462|Syntrophobacterales	28221|Deltaproteobacteria	E	PFAM Pyruvate carboxyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	HMGL-like,dCache_1
k59_38342_1	631362.Thi970DRAFT_03296	4.15e-55	179.0	COG3267@1|root,COG3267@2|Bacteria,1REWJ@1224|Proteobacteria,1S518@1236|Gammaproteobacteria,1X0QD@135613|Chromatiales	1236|Gammaproteobacteria	U	Type II secretory pathway, component ExeA	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22
k59_68683_1	111780.Sta7437_0246	8.71e-11	63.9	COG3216@1|root,COG3216@2|Bacteria,1G7YZ@1117|Cyanobacteria,3VJZF@52604|Pleurocapsales	1117|Cyanobacteria	S	Uncharacterized protein conserved in bacteria (DUF2062)	-	-	-	ko:K09928	-	-	-	-	ko00000	-	-	-	DUF2062
k59_68683_2	1121405.dsmv_0566	7.01e-45	158.0	COG0030@1|root,COG0030@2|Bacteria,1MVNU@1224|Proteobacteria,42QAC@68525|delta/epsilon subdivisions,2WN8H@28221|Deltaproteobacteria,2MIAF@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
k59_91304_1	880072.Desac_0689	6.17e-77	249.0	COG1154@1|root,COG1154@2|Bacteria,1MUSJ@1224|Proteobacteria,42M35@68525|delta/epsilon subdivisions,2WIX5@28221|Deltaproteobacteria,2MQAA@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)	dxs	-	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	-	DXP_synthase_N,Transket_pyr,Transketolase_C
k59_45839_1	1121396.KB892913_gene116	2.46e-114	344.0	COG0517@1|root,COG0517@2|Bacteria,1MXI6@1224|Proteobacteria,42WI2@68525|delta/epsilon subdivisions,2WRPD@28221|Deltaproteobacteria,2MQ18@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Transposase zinc-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Y2_Tnp,Zn_Tnp_IS91
k59_45839_2	1121396.KB892913_gene117	3.92e-74	235.0	COG4974@1|root,COG4974@2|Bacteria,1MVAN@1224|Proteobacteria,42N7M@68525|delta/epsilon subdivisions,2X5JU@28221|Deltaproteobacteria,2MPFA@213118|Desulfobacterales	28221|Deltaproteobacteria	L	Phage integrase, N-terminal SAM-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
k59_61165_1	1121405.dsmv_2227	5.15e-83	264.0	28HQ2@1|root,2Z7XV@2|Bacteria,1P4Z7@1224|Proteobacteria,42NSG@68525|delta/epsilon subdivisions,2WJ6K@28221|Deltaproteobacteria,2MJCF@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_189895_1	1049564.TevJSym_as00320	5.34e-90	271.0	COG0501@1|root,COG0501@2|Bacteria,1MUNA@1224|Proteobacteria,1RMZ6@1236|Gammaproteobacteria,1J5TZ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	O	COG0501 Zn-dependent protease with chaperone function	Z012_09445	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
k59_30729_1	237368.SCABRO_00286	1.83e-11	62.4	COG0614@1|root,COG0614@2|Bacteria,2J0J0@203682|Planctomycetes	203682|Planctomycetes	P	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_3
k59_91308_1	335543.Sfum_1795	2.65e-168	484.0	COG3383@1|root,COG3383@2|Bacteria,1QTZB@1224|Proteobacteria,42SPZ@68525|delta/epsilon subdivisions,2WIV9@28221|Deltaproteobacteria,2MRHE@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Fer2_4,Fer4_7,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
k59_30731_1	573370.DMR_10790	8.72e-12	70.5	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MR8@68525|delta/epsilon subdivisions,2WIUA@28221|Deltaproteobacteria,2MA08@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	histidine kinase HAMP region domain protein	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
k59_197557_1	1501230.ET33_08420	1.19e-22	98.2	COG5441@1|root,COG5441@2|Bacteria,1TQ3W@1239|Firmicutes,4HATW@91061|Bacilli,26SAD@186822|Paenibacillaceae	91061|Bacilli	S	Uncharacterised protein family (UPF0261)	-	-	-	-	-	-	-	-	-	-	-	-	UPF0261
k59_91319_1	880072.Desac_2468	1.29e-60	197.0	COG3568@1|root,COG3568@2|Bacteria,1PPNP@1224|Proteobacteria,42QW2@68525|delta/epsilon subdivisions,2WMRN@28221|Deltaproteobacteria,2MRQ9@213462|Syntrophobacterales	28221|Deltaproteobacteria	L	PFAM Endonuclease Exonuclease phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
k59_167135_1	485915.Dret_1635	1.4e-41	143.0	2A1M5@1|root,30PV9@2|Bacteria,1N5W2@1224|Proteobacteria,42RI6@68525|delta/epsilon subdivisions,2WNKT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_189900_1	96561.Dole_1001	1.7e-56	191.0	COG1150@1|root,COG1150@2|Bacteria,1QUKA@1224|Proteobacteria,42MNE@68525|delta/epsilon subdivisions,2WIN3@28221|Deltaproteobacteria,2MHSC@213118|Desulfobacterales	28221|Deltaproteobacteria	C	4Fe-4S dicluster domain	qmoC	-	-	ko:K16887	-	-	-	-	ko00000	-	-	-	Fer4_17,Fer4_8,Fer4_9,Nitrate_red_gam
k59_167137_1	1265505.ATUG01000001_gene4046	1.9e-45	167.0	COG0642@1|root,COG4191@1|root,COG2205@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MC4@68525|delta/epsilon subdivisions,2WIU5@28221|Deltaproteobacteria,2MIV8@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS_9,Response_reg
k59_235469_1	526222.Desal_1095	2.8e-24	103.0	COG0845@1|root,COG0845@2|Bacteria,1RI9S@1224|Proteobacteria,42T1D@68525|delta/epsilon subdivisions,2X5J9@28221|Deltaproteobacteria,2MGRU@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
k59_144444_2	177437.HRM2_15130	4.8e-47	165.0	COG5557@1|root,COG5557@2|Bacteria,1QURB@1224|Proteobacteria,43BT1@68525|delta/epsilon subdivisions,2X73S@28221|Deltaproteobacteria,2MMX3@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Pfam Polysulphide reductase, NrfD	actF	-	-	-	-	-	-	-	-	-	-	-	-
k59_129315_1	318464.IO99_12340	1.11e-14	74.7	COG4659@1|root,COG4659@2|Bacteria,1V7R1@1239|Firmicutes,24JVM@186801|Clostridia,36K2X@31979|Clostridiaceae	186801|Clostridia	C	Part of a membrane complex involved in electron transport	rnfG	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K03612	-	-	-	-	ko00000	-	-	-	FMN_bind
k59_129315_2	1121344.JHZO01000004_gene1160	4.38e-10	60.8	COG4658@1|root,COG4658@2|Bacteria,1TQAY@1239|Firmicutes,247TM@186801|Clostridia,3WGC0@541000|Ruminococcaceae	186801|Clostridia	C	Part of a membrane complex involved in electron transport	rnfD	-	-	ko:K03614	-	-	-	-	ko00000	-	-	-	NQR2_RnfD_RnfE
k59_23163_1	1162668.LFE_1103	2.81e-31	126.0	COG0741@1|root,COG1388@1|root,COG0741@2|Bacteria,COG1388@2|Bacteria,3J0J4@40117|Nitrospirae	40117|Nitrospirae	M	Lysin motif	-	-	-	ko:K08307	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	LysM,SLT
k59_144445_1	1041930.Mtc_1312	2.81e-14	69.3	COG1888@1|root,arCOG04140@2157|Archaea,2Y02A@28890|Euryarchaeota	28890|Euryarchaeota	S	protein conserved in archaea	-	-	-	ko:K09732	-	-	-	-	ko00000	-	-	-	DUF211
k59_174830_1	1094980.Mpsy_1446	5.29e-47	159.0	COG1830@1|root,arCOG04044@2157|Archaea,2XTBQ@28890|Euryarchaeota,2N93C@224756|Methanomicrobia	224756|Methanomicrobia	E	Catalyzes a transaldol reaction between 6-deoxy-5- ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2- amino-3,7-dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids	-	-	2.2.1.10,4.1.2.13	ko:K16306	ko00010,ko00030,ko00051,ko00400,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00400,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001	R01068,R01070,R02568,R08568	RC00438,RC00439,RC00721,RC02301	ko00000,ko00001,ko00002,ko01000	-	-	-	DeoC
k59_114103_1	1304284.L21TH_0287	3.54e-38	147.0	COG0539@1|root,COG0761@1|root,COG0539@2|Bacteria,COG0761@2|Bacteria,1TQ9N@1239|Firmicutes,247UK@186801|Clostridia,36DPA@31979|Clostridiaceae	186801|Clostridia	J	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis	ispH	-	1.17.7.4	ko:K02945,ko:K03527	ko00900,ko01100,ko01110,ko01130,ko03010,map00900,map01100,map01110,map01130,map03010	M00096,M00178	R05884,R08210	RC01137,RC01487	br01610,ko00000,ko00001,ko00002,ko01000,ko03011	-	-	-	LYTB,S1
k59_45869_1	177437.HRM2_11030	9.43e-49	174.0	COG4796@1|root,COG4796@2|Bacteria,1QTT6@1224|Proteobacteria,42MKN@68525|delta/epsilon subdivisions,2WJV6@28221|Deltaproteobacteria,2MHUC@213118|Desulfobacterales	28221|Deltaproteobacteria	U	type II and III secretion system protein	pilQ	-	-	ko:K02666	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	AMIN,STN,Secretin,Secretin_N
k59_189905_1	1442599.JAAN01000020_gene2591	5.59e-109	323.0	COG2801@1|root,COG2801@2|Bacteria,1MVXQ@1224|Proteobacteria,1RSHU@1236|Gammaproteobacteria,1X4HC@135614|Xanthomonadales	135614|Xanthomonadales	L	Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_21,rve
k59_83772_1	796945.HMPREF1145_1625	0.00097	46.2	COG1776@1|root,COG1776@2|Bacteria,1UNKB@1239|Firmicutes,247MX@186801|Clostridia,2PRCB@265975|Oribacterium	186801|Clostridia	NT	Chemotaxis phosphatase CheX	cheC	-	-	ko:K03410	ko02030,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheC
k59_38358_1	745014.OMB55_00022110	9.27e-42	145.0	COG0500@1|root,COG2226@2|Bacteria,1MVSY@1224|Proteobacteria,1S24V@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	Methionine biosynthesis protein MetW	metW	-	-	-	-	-	-	-	-	-	-	-	MetW
k59_114110_1	1317122.ATO12_23440	2e-55	180.0	COG0288@1|root,COG0288@2|Bacteria,4NH0X@976|Bacteroidetes,1HXY7@117743|Flavobacteriia,2YI1C@290174|Aquimarina	976|Bacteroidetes	P	Carbonic anhydrase	-	-	4.2.1.1	ko:K01673	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Pro_CA
k59_91345_3	477974.Daud_1943	7.78e-23	95.5	COG2131@1|root,COG2131@2|Bacteria,1V3PU@1239|Firmicutes,24HF0@186801|Clostridia,261R0@186807|Peptococcaceae	186801|Clostridia	F	PFAM Cytidine and deoxycytidylate deaminase zinc-binding region	comEB	-	3.5.4.12	ko:K01493	ko00240,ko01100,map00240,map01100	M00429	R01663	RC00074	ko00000,ko00001,ko00002,ko01000,ko02044	-	-	-	dCMP_cyt_deam_1
k59_167158_1	1121405.dsmv_2874	1.64e-20	89.7	COG0314@1|root,COG0746@1|root,COG0314@2|Bacteria,COG0746@2|Bacteria,1RKCH@1224|Proteobacteria,42T8X@68525|delta/epsilon subdivisions,2WP3Q@28221|Deltaproteobacteria,2MK7Z@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor	mobA	-	2.7.7.77	ko:K03752	ko00790,ko01100,map00790,map01100	-	R11581	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
k59_23179_1	370438.PTH_1043	1.46e-37	144.0	COG0608@1|root,COG0608@2|Bacteria,1TPXE@1239|Firmicutes,247NU@186801|Clostridia,25ZYA@186807|Peptococcaceae	186801|Clostridia	L	TIGRFAM single-stranded-DNA-specific exonuclease RecJ	recJ	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1,Helicase_C
k59_205202_1	552811.Dehly_0051	2.7e-42	150.0	COG2801@1|root,COG2801@2|Bacteria	2|Bacteria	L	transposition	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_91357_1	338963.Pcar_3052	1.8e-77	248.0	COG3666@1|root,COG3666@2|Bacteria,1N3QR@1224|Proteobacteria,42N7X@68525|delta/epsilon subdivisions,2WMM9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_6,DUF772
k59_159494_1	338963.Pcar_0712	5.45e-41	138.0	COG0198@1|root,COG0198@2|Bacteria,1MZQD@1224|Proteobacteria,42TGC@68525|delta/epsilon subdivisions,2WQ2G@28221|Deltaproteobacteria,43VB6@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Ribosomal proteins 50S L24/mitochondrial 39S L24	rplX	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02895	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KOW,ribosomal_L24
k59_136728_2	96561.Dole_1861	7.5e-36	131.0	COG3547@1|root,COG3547@2|Bacteria	2|Bacteria	L	Transposase (IS116 IS110 IS902 family)	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_151910_1	944479.JQLX01000010_gene573	1.64e-19	86.7	COG1396@1|root,COG1917@1|root,COG1396@2|Bacteria,COG1917@2|Bacteria,1MVQY@1224|Proteobacteria,42REC@68525|delta/epsilon subdivisions,2WNN1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,HTH_3
k59_45707_1	106582.XP_004539855.1	0.000195	50.4	COG0484@1|root,KOG0712@2759|Eukaryota,38CPQ@33154|Opisthokonta,3BCGW@33208|Metazoa,3CWJE@33213|Bilateria,485P9@7711|Chordata,4910D@7742|Vertebrata,49XJS@7898|Actinopterygii	33208|Metazoa	O	homolog subfamily A member	DNAJA2	GO:0001671,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005829,GO:0006457,GO:0006950,GO:0008047,GO:0008150,GO:0008152,GO:0008284,GO:0009987,GO:0010033,GO:0018885,GO:0030234,GO:0032781,GO:0035966,GO:0042026,GO:0042127,GO:0042221,GO:0043085,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043462,GO:0044093,GO:0044424,GO:0044444,GO:0044464,GO:0048518,GO:0048522,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051082,GO:0051087,GO:0051336,GO:0051345,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0071704,GO:0098772	-	ko:K09502,ko:K09503	ko04141,map04141	-	-	-	ko00000,ko00001,ko03029,ko03110,ko04131	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
k59_235321_1	748727.CLJU_c09940	4.03e-05	50.8	COG0457@1|root,COG0463@1|root,COG0457@2|Bacteria,COG0463@2|Bacteria,1TSF5@1239|Firmicutes,25B5G@186801|Clostridia,36WAT@31979|Clostridiaceae	186801|Clostridia	M	PFAM Glycosyl transferase family 2	-	-	-	ko:K00786	-	-	-	-	ko00000,ko01000	-	-	-	Glycos_transf_2,TPR_2,TPR_8
k59_121601_1	483219.LILAB_17260	8.38e-39	149.0	COG3316@1|root,COG3599@1|root,COG3316@2|Bacteria,COG3599@2|Bacteria,1QWDK@1224|Proteobacteria,43CXP@68525|delta/epsilon subdivisions,2X85T@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	Transposase IS66 family	-	-	-	ko:K07484	-	-	-	-	ko00000	-	-	-	DDE_Tnp_IS66
k59_235322_1	1121422.AUMW01000003_gene836	1.45e-31	120.0	COG2267@1|root,COG2267@2|Bacteria,1V4GY@1239|Firmicutes,25EJZ@186801|Clostridia,261ST@186807|Peptococcaceae	186801|Clostridia	I	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
k59_235322_2	1121472.AQWN01000004_gene835	9.06e-142	420.0	COG0318@1|root,COG0318@2|Bacteria,1TPSX@1239|Firmicutes,248JC@186801|Clostridia,260H6@186807|Peptococcaceae	186801|Clostridia	IQ	Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
k59_121610_2	661478.OP10G_0669	5.49e-18	84.7	COG1082@1|root,COG1082@2|Bacteria	2|Bacteria	G	myo-inosose-2 dehydratase activity	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
k59_167003_1	1265505.ATUG01000001_gene3487	4.04e-40	144.0	COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,42M9N@68525|delta/epsilon subdivisions,2WIZR@28221|Deltaproteobacteria,2MIYC@213118|Desulfobacterales	28221|Deltaproteobacteria	G	Tripartite ATP-independent periplasmic transporter, DctM component	-	-	-	-	-	-	-	-	-	-	-	-	DctM
k59_167003_2	1121396.KB893035_gene3569	2.66e-52	183.0	COG0145@1|root,COG0146@1|root,COG0145@2|Bacteria,COG0146@2|Bacteria,1MU2Y@1224|Proteobacteria,42NFP@68525|delta/epsilon subdivisions,2X7WN@28221|Deltaproteobacteria,2MJWY@213118|Desulfobacterales	28221|Deltaproteobacteria	EQ	Hydantoinase oxoprolinase N-terminal region	-	-	3.5.2.9	ko:K01469	ko00480,map00480	-	R00251	RC00553	ko00000,ko00001,ko01000	-	-	-	Hydant_A_N,Hydantoinase_A,Hydantoinase_B
k59_220213_2	1183377.Py04_1756	6.76e-22	98.2	COG0582@1|root,arCOG01241@2157|Archaea,2XV3E@28890|Euryarchaeota,242ZK@183968|Thermococci	183968|Thermococci	J	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules	xerA	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_int_SAM_4,Phage_integrase
k59_106433_1	483219.LILAB_36230	1.72e-72	226.0	COG2884@1|root,COG2884@2|Bacteria,1MVQ4@1224|Proteobacteria,42MAM@68525|delta/epsilon subdivisions,2WK4Y@28221|Deltaproteobacteria,2YV0E@29|Myxococcales	28221|Deltaproteobacteria	D	ABC transporter	ftsE	-	-	ko:K09812	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	ABC_tran
k59_151926_1	96561.Dole_3250	1.98e-123	369.0	COG3039@1|root,COG3039@2|Bacteria,1QQ9Q@1224|Proteobacteria,42S7X@68525|delta/epsilon subdivisions,2WNJ2@28221|Deltaproteobacteria,2MJG4@213118|Desulfobacterales	28221|Deltaproteobacteria	L	PFAM transposase IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DUF772
k59_235328_1	1232437.KL662015_gene1255	3.46e-39	149.0	COG2909@1|root,COG3187@1|root,COG2909@2|Bacteria,COG3187@2|Bacteria	2|Bacteria	O	response to heat	-	-	-	ko:K03668,ko:K03929	-	-	-	-	ko00000,ko01000	-	CE10	-	GerE,META
k59_53334_1	880070.Cycma_3396	4.35e-71	235.0	COG2183@1|root,COG2183@2|Bacteria,4NETD@976|Bacteroidetes,47MKQ@768503|Cytophagia	976|Bacteroidetes	K	TIGRFAM competence protein ComEA helix-hairpin-helix repeat region	yhgF	-	-	ko:K06959	-	-	-	-	ko00000	-	-	-	HHH_3,S1,Tex_N,Tex_YqgF
k59_144283_1	760568.Desku_1074	3.65e-51	179.0	COG1053@1|root,COG1053@2|Bacteria,1TRE8@1239|Firmicutes,247TH@186801|Clostridia,25ZZD@186807|Peptococcaceae	186801|Clostridia	C	reductase alpha subunit	-	-	1.8.99.2	ko:K00394	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00596	R00860,R04927,R08553	RC00007,RC01239,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
k59_174665_1	1121405.dsmv_2845	4.27e-116	348.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,42PXA@68525|delta/epsilon subdivisions,2WM6E@28221|Deltaproteobacteria	28221|Deltaproteobacteria	IQ	PFAM AMP-dependent synthetase and ligase	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
k59_91209_1	56780.SYN_01988	8.33e-17	79.0	COG1350@1|root,COG1350@2|Bacteria,1N07Y@1224|Proteobacteria,42MPB@68525|delta/epsilon subdivisions,2WJUV@28221|Deltaproteobacteria,2MQZ7@213462|Syntrophobacterales	28221|Deltaproteobacteria	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB2	-	4.2.1.20	ko:K06001	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
k59_159524_1	330214.NIDE2454	1.8e-81	257.0	COG0114@1|root,COG0114@2|Bacteria,3J0FU@40117|Nitrospirae	40117|Nitrospirae	C	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate	fumC	-	4.2.1.2	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	M00009,M00011,M00173,M00376	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	FumaraseC_C,Lyase_1
k59_197412_1	1347086.CCBA010000010_gene1717	1.21e-102	310.0	COG1541@1|root,COG1541@2|Bacteria,1TQA1@1239|Firmicutes,4HAU0@91061|Bacilli,1ZBRF@1386|Bacillus	91061|Bacilli	H	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)	paaK	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C_2
k59_121617_1	1123054.KB907702_gene1639	5.74e-27	112.0	COG2972@1|root,COG2972@2|Bacteria,1MXVQ@1224|Proteobacteria,1RQDA@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	signal transduction protein with a C-terminal ATPase domain	-	-	2.7.13.3	ko:K08082	ko02020,map02020	M00493	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,His_kinase
k59_151943_1	1121405.dsmv_2060	4.58e-82	250.0	COG2834@1|root,COG2834@2|Bacteria,1R5U8@1224|Proteobacteria,42MIS@68525|delta/epsilon subdivisions,2WMK7@28221|Deltaproteobacteria,2MJNM@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Outer membrane lipoprotein-sorting protein	-	-	-	-	-	-	-	-	-	-	-	-	LolA_like
k59_53346_2	177437.HRM2_17610	2.87e-47	158.0	COG4662@1|root,COG4662@2|Bacteria,1MZVS@1224|Proteobacteria,42N6T@68525|delta/epsilon subdivisions,2WMKR@28221|Deltaproteobacteria,2MIW9@213118|Desulfobacterales	28221|Deltaproteobacteria	P	PFAM binding-protein-dependent transport systems inner membrane component	tupB	-	-	ko:K05773	ko02010,map02010	M00186	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.2,3.A.1.6.4	-	-	BPD_transp_1
k59_98836_1	335543.Sfum_3643	2.19e-142	417.0	COG0263@1|root,COG0263@2|Bacteria,1MUBG@1224|Proteobacteria,42NEA@68525|delta/epsilon subdivisions,2WIVS@28221|Deltaproteobacteria,2MQBU@213462|Syntrophobacterales	28221|Deltaproteobacteria	F	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate	proB	GO:0003674,GO:0003824,GO:0004349,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0018130,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.2.11	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	M00015	R00239	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_3198	AA_kinase,PUA
k59_91224_1	521719.ATXQ01000001_gene456	4.38e-05	46.2	COG0642@1|root,COG0642@2|Bacteria,1MX6R@1224|Proteobacteria,1RPMH@1236|Gammaproteobacteria,1YD12@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
k59_91224_2	237368.SCABRO_01069	1.05e-24	104.0	COG2204@1|root,COG2204@2|Bacteria	2|Bacteria	T	phosphorelay signal transduction system	-	-	-	ko:K07713	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
k59_227705_1	56780.SYN_01263	3.6e-31	122.0	COG1127@1|root,COG2199@1|root,COG1127@2|Bacteria,COG2199@2|Bacteria,1MUSD@1224|Proteobacteria,42NI4@68525|delta/epsilon subdivisions,2WKRT@28221|Deltaproteobacteria,2MQX9@213462|Syntrophobacterales	28221|Deltaproteobacteria	Q	ABC transporter	-	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran,GGDEF
k59_113997_1	1121396.KB893035_gene3592	1.8e-146	431.0	COG0696@1|root,COG0696@2|Bacteria,1MUQ1@1224|Proteobacteria,42N6C@68525|delta/epsilon subdivisions,2WJ66@28221|Deltaproteobacteria,2MIE2@213118|Desulfobacterales	28221|Deltaproteobacteria	G	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate	gpmI	-	5.4.2.12	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,Phosphodiest,iPGM_N
k59_136760_1	1121405.dsmv_1982	2.83e-98	295.0	COG2876@1|root,COG2876@2|Bacteria,1QVAD@1224|Proteobacteria,42MU4@68525|delta/epsilon subdivisions,2WJ8Y@28221|Deltaproteobacteria,2MJBB@213118|Desulfobacterales	28221|Deltaproteobacteria	E	PFAM DAHP synthetase I	-	-	2.5.1.54,5.4.99.5	ko:K03856,ko:K04516	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022,M00024,M00025	R01715,R01826	RC00435,RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	CM_2,DAHP_synth_1
k59_23033_1	679937.Bcop_1802	1.83e-08	59.3	COG2801@1|root,COG2963@1|root,COG2801@2|Bacteria,COG2963@2|Bacteria,4NM64@976|Bacteroidetes,2FS2W@200643|Bacteroidia,4AVKT@815|Bacteroidaceae	976|Bacteroidetes	L	SPTR Prolipoprotein diacylglyceryl transferase	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	rve
k59_23033_2	762903.Pedsa_3732	1.62e-63	205.0	COG2801@1|root,COG2801@2|Bacteria,4NM64@976|Bacteroidetes,1IS2R@117747|Sphingobacteriia	976|Bacteroidetes	L	PFAM Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	rve
k59_7905_1	1121438.JNJA01000009_gene4169	7.89e-101	297.0	COG0491@1|root,COG0491@2|Bacteria,1PHBX@1224|Proteobacteria,43EAP@68525|delta/epsilon subdivisions,2X9C9@28221|Deltaproteobacteria,2MAVY@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
k59_83660_1	335543.Sfum_1330	1.8e-104	311.0	COG2006@1|root,COG2006@2|Bacteria,1QMGX@1224|Proteobacteria,42PRJ@68525|delta/epsilon subdivisions,2WMFN@28221|Deltaproteobacteria,2MQHV@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF362)	-	-	-	-	-	-	-	-	-	-	-	-	DUF362
k59_114000_2	1125863.JAFN01000001_gene167	6.74e-117	342.0	COG0410@1|root,COG0410@2|Bacteria,1MVVC@1224|Proteobacteria,42N2W@68525|delta/epsilon subdivisions,2WJRB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	PFAM ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
k59_205040_2	1232437.KL662058_gene3945	2.95e-34	132.0	COG3850@1|root,COG4191@1|root,COG3850@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42NFY@68525|delta/epsilon subdivisions,2WJKV@28221|Deltaproteobacteria,2MIPK@213118|Desulfobacterales	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_9
k59_53358_1	1232437.KL661965_gene3272	6.85e-54	177.0	COG1414@1|root,COG1414@2|Bacteria,1MUNW@1224|Proteobacteria,42M2F@68525|delta/epsilon subdivisions,2WKUG@28221|Deltaproteobacteria,2MM3S@213118|Desulfobacterales	28221|Deltaproteobacteria	K	helix_turn_helix isocitrate lyase regulation	-	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR,IclR
k59_114001_1	1121405.dsmv_1649	2.89e-82	272.0	COG0449@1|root,COG0449@2|Bacteria,1MW4K@1224|Proteobacteria,42KZ7@68525|delta/epsilon subdivisions,2WJP6@28221|Deltaproteobacteria,2MIWZ@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	iAF987.Gmet_1487	GATase_6,SIS
k59_121628_1	177437.HRM2_41800	2.61e-55	187.0	2DBU2@1|root,2ZB3S@2|Bacteria,1N1MT@1224|Proteobacteria,42VJX@68525|delta/epsilon subdivisions,2WSPP@28221|Deltaproteobacteria,2MNKM@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_4
k59_144325_1	1262449.CP6013_3928	1.47e-05	49.3	COG3267@1|root,COG3267@2|Bacteria,1TRGM@1239|Firmicutes,24EPV@186801|Clostridia,36HUB@31979|Clostridiaceae	186801|Clostridia	U	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22
k59_7917_1	909663.KI867150_gene2389	7.5e-57	187.0	COG0642@1|root,COG2205@2|Bacteria,1MW8M@1224|Proteobacteria,42QF7@68525|delta/epsilon subdivisions,2WJAU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K07644	ko02020,map02020	M00452,M00745	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS_9,Response_reg
k59_23039_4	156889.Mmc1_2892	1.55e-48	166.0	28H75@1|root,2Z7JG@2|Bacteria,1MU3Y@1224|Proteobacteria,2TVB5@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Phage major capsid protein E	-	-	-	-	-	-	-	-	-	-	-	-	Phage_cap_E
k59_197427_1	1206744.BAGL01000063_gene4747	1.38e-06	55.5	COG0318@1|root,COG3321@1|root,COG3882@1|root,COG0318@2|Bacteria,COG3321@2|Bacteria,COG3882@2|Bacteria,2H477@201174|Actinobacteria,4FU0A@85025|Nocardiaceae	201174|Actinobacteria	Q	Acyl transferase domain in polyketide synthase (PKS) enzymes.	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,Acyl_transf_1,Condensation,KAsynt_C_assoc,KR,Ketoacyl-synt_C,PP-binding,PS-DH,ketoacyl-synt
k59_91238_2	1499683.CCFF01000017_gene1836	1.01e-07	54.3	COG4658@1|root,COG4658@2|Bacteria,1TQAY@1239|Firmicutes,247TM@186801|Clostridia,36FI0@31979|Clostridiaceae	186801|Clostridia	C	Part of a membrane complex involved in electron transport	rnfD	-	-	ko:K03614	-	-	-	-	ko00000	-	-	-	NQR2_RnfD_RnfE
k59_205058_1	1121396.KB893100_gene4325	1.26e-41	151.0	COG0661@1|root,COG0661@2|Bacteria,1MW1J@1224|Proteobacteria,42T05@68525|delta/epsilon subdivisions,2WPA4@28221|Deltaproteobacteria,2MNJS@213118|Desulfobacterales	28221|Deltaproteobacteria	S	ABC1 family	-	-	-	-	-	-	-	-	-	-	-	-	ABC1,APH
k59_296_2	1121423.JONT01000051_gene922	2.3e-57	195.0	COG4422@1|root,COG4422@2|Bacteria,1TPRY@1239|Firmicutes,247VT@186801|Clostridia,264JU@186807|Peptococcaceae	186801|Clostridia	S	Protein of unknown function (DUF5131)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5131
k59_296_4	1094557.ME3_01290	1.51e-12	69.7	COG0817@1|root,COG0817@2|Bacteria,1RCYK@1224|Proteobacteria,2U727@28211|Alphaproteobacteria,48U1J@772|Bartonellaceae	28211|Alphaproteobacteria	L	genomic island protein Bartonella henselae str. Houston-1 gi 49238285 emb CAF27499.1 and to	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_296_7	99598.Cal7507_1583	2.57e-37	138.0	COG0305@1|root,COG0305@2|Bacteria,1G0R8@1117|Cyanobacteria,1HJAT@1161|Nostocales	1117|Cyanobacteria	L	Participates in initiation and elongation during chromosome replication	dnaB	GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0032392,GO:0032508,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C,Intein_splicing,LAGLIDADG_3
k59_174680_1	485915.Dret_2383	3.12e-100	303.0	COG3303@1|root,COG3303@2|Bacteria,1P8CP@1224|Proteobacteria,42MXS@68525|delta/epsilon subdivisions,2WKEK@28221|Deltaproteobacteria,2M8WD@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	Seven times multi-haem cytochrome CxxCH	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554,Multi-haem_cyto
k59_151967_1	1121405.dsmv_3317	1.36e-136	401.0	COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,42MEA@68525|delta/epsilon subdivisions,2WIW6@28221|Deltaproteobacteria,2MI74@213118|Desulfobacterales	28221|Deltaproteobacteria	KT	Sigma-54 interaction domain	-	-	2.1.1.80	ko:K00575	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	HTH_8,PAS_4,PAS_9,Sigma54_activat
k59_68597_2	706587.Desti_1890	5.28e-21	95.9	COG0479@1|root,COG0723@1|root,COG0479@2|Bacteria,COG0723@2|Bacteria,1MVHS@1224|Proteobacteria,42M2J@68525|delta/epsilon subdivisions,2WJMH@28221|Deltaproteobacteria,2MQFY@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein	sdhB	-	1.3.5.1,1.3.5.4	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_3,Fer4_10,Fer4_8
k59_220249_1	335543.Sfum_1184	2.51e-113	348.0	COG0457@1|root,COG2114@1|root,COG5616@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG5616@2|Bacteria,1PFB9@1224|Proteobacteria,437WC@68525|delta/epsilon subdivisions,2X35Z@28221|Deltaproteobacteria,2MS2F@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_46428_1	880072.Desac_2093	2.19e-48	163.0	COG2877@1|root,COG2877@2|Bacteria,1MV91@1224|Proteobacteria,42M61@68525|delta/epsilon subdivisions,2WIXU@28221|Deltaproteobacteria,2MQA2@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	PFAM DAHP synthetase I	kdsA	-	2.5.1.55	ko:K01627	ko00540,ko01100,map00540,map01100	M00063	R03254	RC00435	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	DAHP_synth_1
k59_46428_2	1167006.UWK_00897	6.13e-62	206.0	COG0504@1|root,COG0504@2|Bacteria,1MUIT@1224|Proteobacteria,42MEU@68525|delta/epsilon subdivisions,2WJ0F@28221|Deltaproteobacteria,2MHTP@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1276	CTP_synth_N,GATase
k59_198060_1	551275.KB899546_gene2241	5.65e-14	78.2	28M5W@1|root,2ZAJK@2|Bacteria,1R5C9@1224|Proteobacteria,2U7DQ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_129835_1	1121935.AQXX01000139_gene2999	7.26e-16	78.2	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,1RSDZ@1236|Gammaproteobacteria,1XIZU@135619|Oceanospirillales	135619|Oceanospirillales	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
k59_129835_2	56780.SYN_01093	2.21e-66	219.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,2MRFN@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	Bacterial regulatory protein, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
k59_31274_1	237368.SCABRO_02098	1.86e-111	345.0	COG0574@1|root,COG3848@1|root,COG0574@2|Bacteria,COG3848@2|Bacteria,2IX0T@203682|Planctomycetes	203682|Planctomycetes	GT	Pyruvate phosphate dikinase, PEP/pyruvate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	PEP-utilizers,PPDK_N
k59_31274_2	472759.Nhal_3535	8.05e-31	114.0	COG0748@1|root,COG0748@2|Bacteria,1N6EJ@1224|Proteobacteria	1224|Proteobacteria	P	Pfam Pyridoxamine 5'-phosphate	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
k59_46436_1	1121405.dsmv_0316	1.69e-51	181.0	COG1048@1|root,COG1048@2|Bacteria,1MU9T@1224|Proteobacteria,42M33@68525|delta/epsilon subdivisions,2WJGS@28221|Deltaproteobacteria,2MIFE@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate	-	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
k59_182906_1	1232437.KL661961_gene2966	5.01e-99	317.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,42NAV@68525|delta/epsilon subdivisions,2WJ3W@28221|Deltaproteobacteria,2MIIB@213118|Desulfobacterales	28221|Deltaproteobacteria	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
k59_152654_1	933262.AXAM01000175_gene2920	1.29e-43	142.0	COG2161@1|root,COG2161@2|Bacteria,1N7B5@1224|Proteobacteria,42V0B@68525|delta/epsilon subdivisions,2WS9N@28221|Deltaproteobacteria,2MPES@213118|Desulfobacterales	28221|Deltaproteobacteria	D	Antitoxin Phd_YefM, type II toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
k59_175384_1	1121930.AQXG01000002_gene2050	6.68e-62	207.0	COG0459@1|root,COG0459@2|Bacteria,4NDZM@976|Bacteroidetes,1INP2@117747|Sphingobacteriia	976|Bacteroidetes	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
k59_144993_1	1265505.ATUG01000002_gene1077	1.06e-106	317.0	COG0683@1|root,COG0683@2|Bacteria,1MWJ1@1224|Proteobacteria,42MSJ@68525|delta/epsilon subdivisions,2WKHJ@28221|Deltaproteobacteria,2MITB@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Receptor family ligand binding region	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
k59_122273_2	1122933.JNIY01000003_gene179	1.84e-09	61.2	2B189@1|root,31TNP@2|Bacteria,2GSQX@201174|Actinobacteria,4F2YQ@85016|Cellulomonadaceae	201174|Actinobacteria	S	Ion channel	-	-	-	-	-	-	-	-	-	-	-	-	Ion_trans_2
k59_140796_1	880072.Desac_2749	1.17e-45	162.0	COG2203@1|root,COG3605@1|root,COG2203@2|Bacteria,COG3605@2|Bacteria,1RHTM@1224|Proteobacteria,43F2G@68525|delta/epsilon subdivisions,2X340@28221|Deltaproteobacteria,2MRSC@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	GAF domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2
k59_163026_1	439235.Dalk_4322	4.09e-66	221.0	COG3290@1|root,COG4191@1|root,COG3290@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42PZ5@68525|delta/epsilon subdivisions,2WM5Q@28221|Deltaproteobacteria,2MJDG@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
k59_178033_1	525897.Dbac_0976	1.6e-11	71.2	COG1366@1|root,COG2204@1|root,COG1366@2|Bacteria,COG2204@2|Bacteria,1RCHU@1224|Proteobacteria,42QWT@68525|delta/epsilon subdivisions,2WN23@28221|Deltaproteobacteria,2MAFK@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,STAS,STAS_2
k59_87301_1	882.DVU_1298	9.78e-67	204.0	COG0048@1|root,COG0048@2|Bacteria,1RCWY@1224|Proteobacteria,42RDQ@68525|delta/epsilon subdivisions,2WND8@28221|Deltaproteobacteria,2MBJ6@213115|Desulfovibrionales	28221|Deltaproteobacteria	J	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit	rpsL	-	-	ko:K02950	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosom_S12_S23
k59_216187_1	425104.Ssed_2791	6.3e-25	104.0	COG4262@1|root,COG4262@2|Bacteria,1QUPY@1224|Proteobacteria,1RMJV@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	-	-	-	-	-	-	-	-	-	-	-	-	Spermine_synth
k59_216187_2	425104.Ssed_2790	4.74e-40	139.0	COG2518@1|root,COG2518@2|Bacteria,1MXQC@1224|Proteobacteria,1RMHZ@1236|Gammaproteobacteria,2Q9RW@267890|Shewanellaceae	1236|Gammaproteobacteria	J	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	pcm2	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
k59_41647_1	335543.Sfum_2793	1.37e-49	159.0	COG1144@1|root,COG1144@2|Bacteria,1N99V@1224|Proteobacteria,42V8C@68525|delta/epsilon subdivisions,2WRCP@28221|Deltaproteobacteria,2MS61@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	4Fe-4S dicluster domain	-	-	1.2.7.1	ko:K00171	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4
k59_41647_2	335543.Sfum_2794	4.19e-65	209.0	COG0674@1|root,COG0674@2|Bacteria,1MVM0@1224|Proteobacteria,42MZ0@68525|delta/epsilon subdivisions,2WJG3@28221|Deltaproteobacteria,2MQ4Y@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	ferredoxin oxidoreductase alpha subunit	-	-	1.2.7.1	ko:K00169	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR_N
k59_216189_1	1122621.ATZA01000045_gene3565	2.4e-57	196.0	COG1008@1|root,COG1008@2|Bacteria,4NEJ1@976|Bacteroidetes,1IR24@117747|Sphingobacteriia	976|Bacteroidetes	C	NADH-quinone oxidoreductase, chain M	-	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q5_N,Proton_antipo_M
k59_231894_1	667014.Thein_0250	8.08e-45	155.0	COG0559@1|root,COG0559@2|Bacteria,2GIAU@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	E	Branched-chain amino acid transport system / permease component	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
k59_72493_1	1131269.AQVV01000024_gene2358	1.41e-54	192.0	COG1033@1|root,COG1033@2|Bacteria	2|Bacteria	S	growth of symbiont in host cell	acrB	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
k59_133244_1	891968.Anamo_1467	9.4e-40	150.0	COG2414@1|root,COG2414@2|Bacteria,3TAIE@508458|Synergistetes	508458|Synergistetes	C	Aldehyde ferredoxin oxidoreductase	-	-	1.2.7.5	ko:K03738	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00309	R08571	RC00242	ko00000,ko00001,ko00002,ko01000	-	-	-	AFOR_C,AFOR_N
k59_57462_1	266117.Rxyl_0466	6.45e-53	184.0	COG1473@1|root,COG1473@2|Bacteria,2GNEG@201174|Actinobacteria	201174|Actinobacteria	S	Peptidase, M20	-	-	-	ko:K12941	-	-	-	-	ko00000,ko01002	-	-	-	M20_dimer,Peptidase_M20
k59_19000_1	933262.AXAM01000039_gene1156	1.76e-80	252.0	COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,42NES@68525|delta/epsilon subdivisions,2WJ0V@28221|Deltaproteobacteria,2MHWD@213118|Desulfobacterales	28221|Deltaproteobacteria	NU	type II secretion system	pilC	-	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
k59_87314_1	402777.KB235903_gene401	5.39e-71	242.0	COG0457@1|root,COG3914@1|root,COG0457@2|Bacteria,COG3914@2|Bacteria,1G0YS@1117|Cyanobacteria,1H82I@1150|Oscillatoriales	1117|Cyanobacteria	O	O-linked N-acetylglucosamine transferase SPINDLY family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_41,Glycos_transf_2,Sulfotransfer_2,TPR_1,TPR_11,TPR_16,TPR_17,TPR_19,TPR_2,TPR_8
k59_117412_1	203124.Tery_2136	2.07e-37	143.0	COG1262@1|root,COG1262@2|Bacteria	2|Bacteria	T	PFAM Formylglycine-generating sulfatase enzyme	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,PEGA,Peptidase_C14,Pkinase,TIR_2
k59_209131_1	880072.Desac_0010	1.87e-87	271.0	COG0044@1|root,COG0044@2|Bacteria,1MVXY@1224|Proteobacteria,42MJ9@68525|delta/epsilon subdivisions,2WJH8@28221|Deltaproteobacteria,2MQ49@213462|Syntrophobacterales	28221|Deltaproteobacteria	F	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily	pyrC	GO:0003674,GO:0003824,GO:0004038,GO:0004151,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046390,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
k59_209131_2	96561.Dole_0514	1.38e-36	132.0	COG0540@1|root,COG0540@2|Bacteria,1MWAB@1224|Proteobacteria,42NMR@68525|delta/epsilon subdivisions,2WJQR@28221|Deltaproteobacteria,2MIUY@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Belongs to the ATCase OTCase family	pyrB	GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
k59_140817_1	1089553.Tph_c00740	1.31e-05	50.4	COG1349@1|root,COG1349@2|Bacteria,1VC1B@1239|Firmicutes,24P9E@186801|Clostridia	186801|Clostridia	GK	Protein of unknown function (DUF1670)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1670
k59_95151_1	933262.AXAM01000066_gene1682	2.27e-17	83.2	COG1508@1|root,COG1508@2|Bacteria,1MW4V@1224|Proteobacteria,42M3C@68525|delta/epsilon subdivisions,2WJ21@28221|Deltaproteobacteria,2MHTM@213118|Desulfobacterales	28221|Deltaproteobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	rpoN	-	-	ko:K03092	ko02020,ko05111,map02020,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma54_AID,Sigma54_CBD,Sigma54_DBD
k59_95151_2	998088.B565_0304	2.81e-29	111.0	COG1137@1|root,COG1137@2|Bacteria,1MU8M@1224|Proteobacteria,1RPW1@1236|Gammaproteobacteria,1Y3MI@135624|Aeromonadales	135624|Aeromonadales	S	Branched-chain amino acid ATP-binding cassette transporter	-	-	-	ko:K06861	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	1.B.42.1	-	-	ABC_tran,BCA_ABC_TP_C
k59_102842_1	1123371.ATXH01000012_gene1427	9.47e-58	185.0	COG1051@1|root,COG1051@2|Bacteria,2GI88@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	F	NUDIX domain	-	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
k59_49418_1	224914.BMEI0274	1.02e-45	163.0	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,2TQQ7@28211|Alphaproteobacteria,1J2QE@118882|Brucellaceae	28211|Alphaproteobacteria	I	Belongs to the thiolase family	phbA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
k59_49418_2	671143.DAMO_0994	2.02e-17	79.0	COG1247@1|root,COG1247@2|Bacteria	2|Bacteria	M	phosphinothricin N-acetyltransferase activity	MA20_16670	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
k59_201350_1	933262.AXAM01000014_gene273	9.06e-82	246.0	COG0231@1|root,COG0231@2|Bacteria,1MW2J@1224|Proteobacteria,42N6H@68525|delta/epsilon subdivisions,2WNG7@28221|Deltaproteobacteria,2MHWW@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase	efp	GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
k59_41655_1	335543.Sfum_1464	4.62e-57	202.0	COG2202@1|root,COG3829@1|root,COG2202@2|Bacteria,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,42MEA@68525|delta/epsilon subdivisions,2WIW6@28221|Deltaproteobacteria,2MR33@213462|Syntrophobacterales	28221|Deltaproteobacteria	KT	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HTH_8,PAS_3,PAS_4,Sigma54_activat
k59_34651_1	595494.Tola_0317	2.52e-42	154.0	COG0446@1|root,COG0607@1|root,COG0446@2|Bacteria,COG0607@2|Bacteria,1NR3M@1224|Proteobacteria,1T1WT@1236|Gammaproteobacteria,1Y41B@135624|Aeromonadales	135624|Aeromonadales	P	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Pyr_redox_dim,Rhodanese
k59_155945_1	1121405.dsmv_1447	1.01e-18	80.9	COG1014@1|root,COG1014@2|Bacteria,1R92Y@1224|Proteobacteria,42QJI@68525|delta/epsilon subdivisions,2WMFZ@28221|Deltaproteobacteria,2MJ4M@213118|Desulfobacterales	28221|Deltaproteobacteria	C	TIGRFAM 2-oxoacid acceptor oxidoreductase, gamma subunit, pyruvate 2-ketoisovalerate family	-	-	1.2.7.3	ko:K00177	ko00020,ko00720,ko01100,ko01120,ko01200,map00020,map00720,map01100,map01120,map01200	M00009,M00011,M00173,M00620	R01197	RC00004,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	POR
k59_155945_2	1121405.dsmv_1448	1.15e-72	224.0	COG1013@1|root,COG1013@2|Bacteria,1N0HY@1224|Proteobacteria,42MTM@68525|delta/epsilon subdivisions,2WJS6@28221|Deltaproteobacteria,2MIRW@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain	-	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
k59_209140_1	945713.IALB_0341	3.87e-82	269.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria	2|Bacteria	G	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)	ppdK	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
k59_72517_1	1232437.KL662058_gene3953	1.1e-70	238.0	COG0493@1|root,COG1148@1|root,COG0493@2|Bacteria,COG1148@2|Bacteria,1MU2H@1224|Proteobacteria,42M6X@68525|delta/epsilon subdivisions,2X6YD@28221|Deltaproteobacteria,2MIN8@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_20,Pyr_redox_2
k59_49421_1	521460.Athe_1507	8.59e-50	173.0	COG1541@1|root,COG1541@2|Bacteria,1TQA1@1239|Firmicutes,248G9@186801|Clostridia,42EK2@68295|Thermoanaerobacterales	186801|Clostridia	H	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)	paaK	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C_2
k59_95154_1	1121405.dsmv_0204	5.76e-85	261.0	COG1702@1|root,COG1702@2|Bacteria,1MVDV@1224|Proteobacteria,42N58@68525|delta/epsilon subdivisions,2WIQS@28221|Deltaproteobacteria,2MID1@213118|Desulfobacterales	28221|Deltaproteobacteria	T	PFAM PhoH family protein	phoH2	-	-	ko:K06217	-	-	-	-	ko00000	-	-	-	PhoH
k59_95154_2	177437.HRM2_35760	3.3e-47	158.0	COG1286@1|root,COG1286@2|Bacteria,1RJE1@1224|Proteobacteria,42SCW@68525|delta/epsilon subdivisions,2WPNX@28221|Deltaproteobacteria,2MKBI@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Colicin V production protein	-	-	-	ko:K03558	-	-	-	-	ko00000	-	-	-	Colicin_V
k59_49895_1	479434.Sthe_1344	2.55e-61	202.0	COG0309@1|root,COG0309@2|Bacteria,2G8E4@200795|Chloroflexi,27XEQ@189775|Thermomicrobia	189775|Thermomicrobia	O	AIR synthase related protein, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AIRS,AIRS_C
k59_232475_1	1265505.ATUG01000001_gene4509	1.85e-77	245.0	COG4191@1|root,COG4191@2|Bacteria,1R682@1224|Proteobacteria,42P91@68525|delta/epsilon subdivisions,2WKQI@28221|Deltaproteobacteria,2MJEK@213118|Desulfobacterales	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4,PAS_9
k59_178528_1	269797.Mbar_A1823	8.41e-42	156.0	COG0038@1|root,arCOG02569@2157|Archaea,2XW6N@28890|Euryarchaeota,2N9N7@224756|Methanomicrobia	224756|Methanomicrobia	P	Cl- channel, voltage-gated family protein	-	-	-	ko:K03281	-	-	-	-	ko00000	2.A.49	-	-	CBS,Voltage_CLC
k59_80660_1	635013.TherJR_0588	6.26e-82	264.0	COG0699@1|root,COG0699@2|Bacteria,1TR0Q@1239|Firmicutes,24BWJ@186801|Clostridia,261EP@186807|Peptococcaceae	186801|Clostridia	S	Dynamin family	-	-	-	-	-	-	-	-	-	-	-	-	Dynamin_N
k59_216741_1	1123371.ATXH01000020_gene478	8.32e-15	74.3	COG1579@1|root,COG1579@2|Bacteria,2GH3N@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	S	C4-type zinc ribbon domain	-	-	-	ko:K07164	-	-	-	-	ko00000	-	-	-	zf-RING_7
k59_19531_1	335543.Sfum_2845	5.8e-91	275.0	COG1073@1|root,COG1073@2|Bacteria,1RBV1@1224|Proteobacteria,42M9M@68525|delta/epsilon subdivisions,2WM64@28221|Deltaproteobacteria,2MQDT@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Serine aminopeptidase, S33	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Hydrolase_4
k59_110890_1	335543.Sfum_0700	8.1e-33	120.0	COG0704@1|root,COG0704@2|Bacteria,1MUMI@1224|Proteobacteria,42QWG@68525|delta/epsilon subdivisions,2WNCJ@28221|Deltaproteobacteria,2MQJC@213462|Syntrophobacterales	28221|Deltaproteobacteria	P	Plays a role in the regulation of phosphate uptake	-	-	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
k59_103344_1	589865.DaAHT2_0484	9.61e-65	211.0	COG3666@1|root,COG3666@2|Bacteria,1N3QR@1224|Proteobacteria,42N7X@68525|delta/epsilon subdivisions,2WMM9@28221|Deltaproteobacteria,2MMU3@213118|Desulfobacterales	28221|Deltaproteobacteria	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_6,DUF772
k59_209614_1	243231.GSU2327	4.36e-69	222.0	COG2907@1|root,COG2907@2|Bacteria,1MV4Z@1224|Proteobacteria,42N4S@68525|delta/epsilon subdivisions,2WJXX@28221|Deltaproteobacteria,43UK3@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
k59_201916_1	1242864.D187_002235	0.000108	52.8	COG0683@1|root,COG1729@1|root,COG0683@2|Bacteria,COG1729@2|Bacteria,1R8IG@1224|Proteobacteria,42N7H@68525|delta/epsilon subdivisions,2WIUQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	ABC-type branched-chain amino acid transport	-	-	-	ko:K07121	-	-	-	-	ko00000	-	-	-	LppC,Peripla_BP_6,TPR_16,TPR_6
k59_49898_1	589865.DaAHT2_1875	2.07e-121	372.0	COG1185@1|root,COG1185@2|Bacteria,1MVB9@1224|Proteobacteria,42MTZ@68525|delta/epsilon subdivisions,2WJCE@28221|Deltaproteobacteria,2MIS9@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004654,GO:0005488,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
k59_216742_1	986075.CathTA2_2774	9.62e-96	290.0	COG0444@1|root,COG0444@2|Bacteria,1TP6E@1239|Firmicutes,4HA4E@91061|Bacilli	91061|Bacilli	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K02031,ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
k59_35182_1	298386.PBPRA1265	1.69e-93	295.0	COG2015@1|root,COG2015@2|Bacteria,1MU82@1224|Proteobacteria,1RMHR@1236|Gammaproteobacteria,1XUC7@135623|Vibrionales	135623|Vibrionales	Q	COG2015 Alkyl sulfatase and related hydrolases	-	-	-	ko:K01138	-	-	-	-	ko00000,ko01000	-	-	-	Alkyl_sulf_C,Alkyl_sulf_dimr,Lactamase_B
k59_148154_3	1121403.AUCV01000056_gene3013	1.75e-58	186.0	COG3678@1|root,COG3678@2|Bacteria,1NW18@1224|Proteobacteria,43048@68525|delta/epsilon subdivisions,2WV68@28221|Deltaproteobacteria,2MNGN@213118|Desulfobacterales	28221|Deltaproteobacteria	NPTU	ATP-independent chaperone mediated protein folding	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_148154_4	525897.Dbac_2183	3.5e-155	445.0	COG0464@1|root,COG0464@2|Bacteria,1QFHD@1224|Proteobacteria,42QEP@68525|delta/epsilon subdivisions,2WIT4@28221|Deltaproteobacteria,2M9XS@213115|Desulfovibrionales	28221|Deltaproteobacteria	O	AAA ATPase central domain protein	-	-	-	-	-	-	-	-	-	-	-	-	AAA,DUF4032
k59_73024_1	880072.Desac_0868	1.39e-16	79.7	COG0683@1|root,COG0683@2|Bacteria,1NHBN@1224|Proteobacteria,42RYV@68525|delta/epsilon subdivisions,2WNEF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	PFAM Extracellular ligand-binding receptor	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
k59_73024_2	1231391.AMZF01000002_gene3226	5.59e-14	74.7	COG0559@1|root,COG0559@2|Bacteria,1P3FU@1224|Proteobacteria,2W967@28216|Betaproteobacteria,3T755@506|Alcaligenaceae	28216|Betaproteobacteria	E	Branched-chain amino acid transport system / permease component	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
k59_12614_1	1122179.KB890413_gene4914	2.62e-10	69.3	COG0739@1|root,COG0739@2|Bacteria,4NGHH@976|Bacteroidetes	976|Bacteroidetes	M	peptidase M23	-	-	-	-	-	-	-	-	-	-	-	-	Glucosaminidase,Peptidase_M23
k59_57958_1	335543.Sfum_4100	1.03e-83	254.0	COG1469@1|root,COG1469@2|Bacteria,1MV1B@1224|Proteobacteria,42N4U@68525|delta/epsilon subdivisions,2WJR7@28221|Deltaproteobacteria,2MQ3Z@213462|Syntrophobacterales	28221|Deltaproteobacteria	F	Converts GTP to 7,8-dihydroneopterin triphosphate	folE2	-	3.5.4.16	ko:K09007	ko00790,ko01100,map00790,map01100	M00126	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	GCHY-1
k59_26908_1	443143.GM18_2767	3.55e-118	345.0	COG1484@1|root,COG1484@2|Bacteria,1MWQX@1224|Proteobacteria,42NG2@68525|delta/epsilon subdivisions,2WK33@28221|Deltaproteobacteria,43V8D@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	IstB-like ATP binding protein	-	-	-	-	-	-	-	-	-	-	-	-	IstB_IS21
k59_26908_2	879212.DespoDRAFT_02827	6.59e-197	562.0	COG4584@1|root,COG4584@2|Bacteria,1MW5J@1224|Proteobacteria,42X93@68525|delta/epsilon subdivisions,2WSXR@28221|Deltaproteobacteria,2MQ06@213118|Desulfobacterales	28221|Deltaproteobacteria	L	PFAM Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	rve
k59_80684_1	177437.HRM2_09430	3.04e-215	605.0	COG3385@1|root,COG3385@2|Bacteria,1R8CS@1224|Proteobacteria,42P9F@68525|delta/epsilon subdivisions,2WKTA@28221|Deltaproteobacteria,2MJAY@213118|Desulfobacterales	28221|Deltaproteobacteria	L	PFAM transposase IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_5,DDE_Tnp_2
k59_133764_1	1192034.CAP_7003	1.65e-96	294.0	COG0626@1|root,COG0626@2|Bacteria,1MU57@1224|Proteobacteria,42M67@68525|delta/epsilon subdivisions,2WJQX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Cys Met metabolism	-	-	2.5.1.48,4.4.1.11,4.4.1.8	ko:K01739,ko:K01760,ko:K01761	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017	R00654,R00782,R00999,R01286,R01288,R02408,R02508,R03217,R03260,R04770,R04941,R04944,R04945,R04946	RC00020,RC00056,RC00069,RC00196,RC00348,RC00382,RC00420,RC00488,RC00710,RC01209,RC01210,RC01245,RC02303,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000	-	-	-	Cys_Met_Meta_PP
k59_100136_1	1304885.AUEY01000072_gene1710	7.72e-73	228.0	COG2605@1|root,COG2605@2|Bacteria,1QW1A@1224|Proteobacteria,42N0X@68525|delta/epsilon subdivisions,2WK4R@28221|Deltaproteobacteria,2MKF9@213118|Desulfobacterales	28221|Deltaproteobacteria	S	GHMP kinases C terminal	-	-	2.7.1.168	ko:K07031	ko00540,map00540	-	R09770	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
k59_31863_1	1121468.AUBR01000046_gene1908	1.26e-40	145.0	COG1082@1|root,COG1082@2|Bacteria,1V1Y1@1239|Firmicutes,24Y9G@186801|Clostridia,42HWD@68295|Thermoanaerobacterales	186801|Clostridia	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
k59_221559_1	1304885.AUEY01000002_gene392	2.18e-34	131.0	COG0457@1|root,COG0457@2|Bacteria,1RCWA@1224|Proteobacteria,42RIH@68525|delta/epsilon subdivisions,2WNE2@28221|Deltaproteobacteria,2MJRW@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_9161_1	909663.KI867150_gene2032	1.84e-84	281.0	COG3829@1|root,COG4191@1|root,COG3829@2|Bacteria,COG4191@2|Bacteria,1PFBE@1224|Proteobacteria,42YSB@68525|delta/epsilon subdivisions,2WU00@28221|Deltaproteobacteria,2MR36@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HisKA
k59_92510_1	880072.Desac_2462	1.39e-97	304.0	COG0449@1|root,COG0449@2|Bacteria,1MW4K@1224|Proteobacteria,42KZ7@68525|delta/epsilon subdivisions,2WJP6@28221|Deltaproteobacteria,2MQ67@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	iAF987.Gmet_1487	GATase_6,SIS
k59_54645_1	1123277.KB893183_gene33	1.86e-77	241.0	COG3385@1|root,COG3385@2|Bacteria	2|Bacteria	L	transposase activity	-	-	-	ko:K07495	-	-	-	-	ko00000	-	-	-	DDE_5,DDE_Tnp_1
k59_16648_1	335543.Sfum_0609	4.61e-131	377.0	COG0437@1|root,COG0437@2|Bacteria,1MU1B@1224|Proteobacteria,42NEG@68525|delta/epsilon subdivisions,2WKHA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	iron-sulfur binding	qrcC	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_7
k59_175983_1	1307759.JOMJ01000003_gene1621	4.24e-46	162.0	COG0124@1|root,COG0124@2|Bacteria,1MV2K@1224|Proteobacteria,42MG0@68525|delta/epsilon subdivisions,2WJE1@28221|Deltaproteobacteria,2M7TH@213115|Desulfovibrionales	28221|Deltaproteobacteria	J	PFAM tRNA synthetase class II (G H P and S)	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
k59_191107_1	243159.AFE_1843	2.95e-57	197.0	COG0021@1|root,COG0021@2|Bacteria,1MUEY@1224|Proteobacteria,1SJQ1@1236|Gammaproteobacteria,2NDRU@225057|Acidithiobacillales	225057|Acidithiobacillales	G	Transketolase, thiamine diphosphate binding domain	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
k59_69786_1	335543.Sfum_0500	9.01e-108	318.0	COG0105@1|root,COG0105@2|Bacteria,1R9ZA@1224|Proteobacteria,42RIR@68525|delta/epsilon subdivisions,2WP3R@28221|Deltaproteobacteria,2MSCP@213462|Syntrophobacterales	28221|Deltaproteobacteria	F	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate	ndk	GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564	2.7.4.6	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	M00049,M00050,M00052,M00053	R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895	RC00002	ko00000,ko00001,ko00002,ko01000,ko04131	-	-	-	NDK
k59_198719_1	1123290.AUDQ01000020_gene697	5.39e-14	79.7	COG4974@1|root,COG4974@2|Bacteria,1TQXV@1239|Firmicutes,4HD04@91061|Bacilli,26ERV@186818|Planococcaceae	91061|Bacilli	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_1,Phage_int_SAM_4,Phage_integrase
k59_153895_1	638303.Thal_0034	2.4e-14	74.3	COG0436@1|root,COG0436@2|Bacteria,2G3VY@200783|Aquificae	200783|Aquificae	E	PFAM Aminotransferase class I and II	-	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
k59_214282_1	1121918.ARWE01000001_gene3199	6.86e-26	113.0	COG2199@1|root,COG2202@1|root,COG4191@1|root,COG5002@1|root,COG2202@2|Bacteria,COG3706@2|Bacteria,COG4191@2|Bacteria,COG5002@2|Bacteria,1RCM9@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_8,PAS_9,Response_reg
k59_115567_1	1183377.Py04_1748	1.28e-50	168.0	COG1491@1|root,arCOG04130@2157|Archaea,2XXAI@28890|Euryarchaeota,242KI@183968|Thermococci	183968|Thermococci	J	Protein of unknown function (DUF655)	-	-	-	ko:K07572	-	-	-	-	ko00000	-	-	-	DUF655
k59_9722_1	1121456.ATVA01000012_gene2655	1.11e-47	171.0	COG1022@1|root,COG1022@2|Bacteria,1MU4D@1224|Proteobacteria,42N2G@68525|delta/epsilon subdivisions,2WIXB@28221|Deltaproteobacteria,2M8U6@213115|Desulfovibrionales	28221|Deltaproteobacteria	I	AMP-dependent synthetase and ligase	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
k59_100728_1	1235798.C817_05211	2.59e-12	72.4	COG1063@1|root,COG1063@2|Bacteria,1TPWP@1239|Firmicutes,248MY@186801|Clostridia	186801|Clostridia	E	Alcohol dehydrogenase zinc-binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
k59_62789_1	1121115.AXVN01000132_gene730	1.54e-08	60.5	COG0546@1|root,COG0546@2|Bacteria,1UHUD@1239|Firmicutes,25E2T@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
k59_161424_1	485915.Dret_1021	2.86e-81	253.0	COG0053@1|root,COG0053@2|Bacteria,1MUDS@1224|Proteobacteria,42NCJ@68525|delta/epsilon subdivisions,2WMIS@28221|Deltaproteobacteria,2MG31@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
k59_85378_1	1232410.KI421424_gene1730	7.74e-53	190.0	COG1352@1|root,COG1352@2|Bacteria,1R6N1@1224|Proteobacteria,42T12@68525|delta/epsilon subdivisions,2WPTY@28221|Deltaproteobacteria,43TRF@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Methyltransferase, chemotaxis proteins	-	-	2.1.1.80	ko:K00575	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheR,CheR_N,Response_reg,TPR_16
k59_2006_1	1265505.ATUG01000002_gene2502	1.62e-86	260.0	COG5012@1|root,COG5012@2|Bacteria,1PXII@1224|Proteobacteria,42UWK@68525|delta/epsilon subdivisions,2X5FM@28221|Deltaproteobacteria,2MNRC@213118|Desulfobacterales	28221|Deltaproteobacteria	S	B12 binding domain	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,B12-binding_2
k59_24747_1	1499967.BAYZ01000028_gene1305	1.39e-113	335.0	COG0683@1|root,COG0683@2|Bacteria	2|Bacteria	E	ABC-type branched-chain amino acid transport systems, periplasmic component	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
k59_146166_1	1265505.ATUG01000001_gene3058	6.42e-73	235.0	2C99Z@1|root,2Z9YV@2|Bacteria,1N0B7@1224|Proteobacteria,42P3M@68525|delta/epsilon subdivisions,2WN6Z@28221|Deltaproteobacteria,2MMGX@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF3373)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3373
k59_191577_1	1265505.ATUG01000001_gene4625	1.2e-168	478.0	COG1024@1|root,COG1024@2|Bacteria,1QY95@1224|Proteobacteria,42N5K@68525|delta/epsilon subdivisions,2WK1G@28221|Deltaproteobacteria,2MHYP@213118|Desulfobacterales	28221|Deltaproteobacteria	I	Enoyl-CoA hydratase/isomerase	bamA	GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009150,GO:0009154,GO:0009166,GO:0009259,GO:0009261,GO:0009987,GO:0016787,GO:0016822,GO:0016823,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0033865,GO:0033869,GO:0033875,GO:0034031,GO:0034032,GO:0034034,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035383,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044273,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901787,GO:1901788	3.7.1.21	ko:K07539	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00541	R05593,R05594,R10696	RC01430,RC01431,RC03237	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
k59_32343_1	880072.Desac_0689	9.41e-82	261.0	COG1154@1|root,COG1154@2|Bacteria,1MUSJ@1224|Proteobacteria,42M35@68525|delta/epsilon subdivisions,2WIX5@28221|Deltaproteobacteria,2MQAA@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)	dxs	-	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	-	DXP_synthase_N,Transket_pyr,Transketolase_C
k59_176469_1	387631.Asulf_02111	1.39e-83	266.0	COG1053@1|root,arCOG00573@2157|Archaea,2XVVQ@28890|Euryarchaeota,2464F@183980|Archaeoglobi	183980|Archaeoglobi	C	adenylylsulfate reductase alpha subunit	-	-	1.8.99.2	ko:K00394	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00596	R00860,R04927,R08553	RC00007,RC01239,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
k59_206928_1	1121405.dsmv_2233	9.68e-26	106.0	2ADFT@1|root,3135W@2|Bacteria,1MY8W@1224|Proteobacteria,42SW3@68525|delta/epsilon subdivisions,2WPYE@28221|Deltaproteobacteria,2MK86@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_32344_1	96561.Dole_0566	5.56e-127	374.0	COG0004@1|root,COG0004@2|Bacteria,1R50W@1224|Proteobacteria,42PKR@68525|delta/epsilon subdivisions,2WM8P@28221|Deltaproteobacteria,2MII5@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Ammonium Transporter Family	-	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
k59_2019_1	1089553.Tph_c19830	1.97e-79	249.0	COG0065@1|root,COG0065@2|Bacteria,1TPE5@1239|Firmicutes,2484F@186801|Clostridia,42F1K@68295|Thermoanaerobacterales	186801|Clostridia	H	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuC	-	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase
k59_85392_1	1283300.ATXB01000001_gene1059	0.000392	43.5	2EB0T@1|root,3351P@2|Bacteria,1NCHM@1224|Proteobacteria,1SJ6Z@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_108171_1	335543.Sfum_1150	9.48e-74	232.0	COG5557@1|root,COG5557@2|Bacteria,1PFX4@1224|Proteobacteria,42NUN@68525|delta/epsilon subdivisions,2WJHN@28221|Deltaproteobacteria,2MQS4@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	PFAM Polysulphide reductase, NrfD	dsrP	-	-	ko:K00185	-	-	-	-	ko00000	5.A.3	-	-	NrfD
k59_9752_1	1121459.AQXE01000001_gene2663	1.26e-38	138.0	COG0492@1|root,COG0492@2|Bacteria,1R82E@1224|Proteobacteria,42PSM@68525|delta/epsilon subdivisions,2WJYX@28221|Deltaproteobacteria,2M8GU@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,Pyr_redox_3
k59_222051_1	56780.SYN_00295	2.56e-48	176.0	COG0366@1|root,COG3408@1|root,COG0366@2|Bacteria,COG3408@2|Bacteria,1MWBZ@1224|Proteobacteria,43AE9@68525|delta/epsilon subdivisions,2X5U3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	Alpha amylase catalytic	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase,GDE_C,GDE_N
k59_62819_1	1304275.C41B8_00145	1.04e-06	51.6	COG3547@1|root,COG3547@2|Bacteria	2|Bacteria	L	Transposase (IS116 IS110 IS902 family)	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_100750_1	1167006.UWK_02275	1.13e-07	51.2	COG4969@1|root,COG4969@2|Bacteria,1QV9X@1224|Proteobacteria,42W4E@68525|delta/epsilon subdivisions,2X70G@28221|Deltaproteobacteria,2MM3H@213118|Desulfobacterales	28221|Deltaproteobacteria	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
k59_78067_1	580340.Tlie_1594	1.3e-63	205.0	COG2199@1|root,COG3829@1|root,COG3706@2|Bacteria,COG3829@2|Bacteria,3TAI8@508458|Synergistetes	508458|Synergistetes	T	PFAM GGDEF domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS_9
k59_184007_1	1168065.DOK_17840	6.85e-24	105.0	COG3291@1|root,COG3291@2|Bacteria,1QXQ7@1224|Proteobacteria,1T3G4@1236|Gammaproteobacteria,1J7AT@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_55352_1	439235.Dalk_3695	2.89e-09	61.6	COG3018@1|root,COG3018@2|Bacteria,1R9S8@1224|Proteobacteria,42RI7@68525|delta/epsilon subdivisions,2WP0N@28221|Deltaproteobacteria,2MIVN@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	LPP20
k59_55352_2	1121405.dsmv_0150	3.55e-16	76.6	COG0061@1|root,COG0061@2|Bacteria,1MUBC@1224|Proteobacteria,42MP8@68525|delta/epsilon subdivisions,2WKMR@28221|Deltaproteobacteria,2MIXA@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	nadK	-	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	NAD_kinase
k59_24774_2	484770.UFO1_0395	1.31e-28	112.0	COG0697@1|root,COG0697@2|Bacteria,1V1H0@1239|Firmicutes,4H40S@909932|Negativicutes	909932|Negativicutes	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
k59_32389_1	439235.Dalk_1047	2.22e-43	148.0	COG0664@1|root,COG0664@2|Bacteria,1RI6M@1224|Proteobacteria,42U8A@68525|delta/epsilon subdivisions,2WPZ6@28221|Deltaproteobacteria,2MKSU@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
k59_32389_2	941449.dsx2_3086	9.7e-73	241.0	COG1132@1|root,COG1132@2|Bacteria,1MWTY@1224|Proteobacteria,42N23@68525|delta/epsilon subdivisions,2WKW2@28221|Deltaproteobacteria,2M7Z1@213115|Desulfovibrionales	28221|Deltaproteobacteria	V	ABC transporter, transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	ABC_membrane,ABC_tran
k59_161478_1	177437.HRM2_03780	3.44e-35	124.0	COG1359@1|root,COG1359@2|Bacteria,1NGPW@1224|Proteobacteria,42TXG@68525|delta/epsilon subdivisions,2WQI4@28221|Deltaproteobacteria,2MKN6@213118|Desulfobacterales	28221|Deltaproteobacteria	S	PFAM Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	ABM
k59_32391_1	880072.Desac_1161	9.07e-31	125.0	COG1042@1|root,COG1042@2|Bacteria,1MW98@1224|Proteobacteria,42KZW@68525|delta/epsilon subdivisions,2WIQB@28221|Deltaproteobacteria,2MQ95@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	CoA binding domain	-	-	6.2.1.13	ko:K01905,ko:K09181,ko:K22224	ko00010,ko00620,ko00640,ko01100,ko01120,map00010,map00620,map00640,map01100,map01120	-	R00229,R00920	RC00004,RC00012,RC00014	ko00000,ko00001,ko01000,ko01004	-	-	-	ATP-grasp_5,Acetyltransf_3,CoA_binding_2,Succ_CoA_lig
k59_168743_1	456442.Mboo_0339	2.63e-15	81.3	COG0642@1|root,arCOG02385@1|root,arCOG05183@1|root,arCOG02385@2157|Archaea,arCOG05183@2157|Archaea,arCOG06192@2157|Archaea,2Y7TZ@28890|Euryarchaeota,2NAUN@224756|Methanomicrobia	224756|Methanomicrobia	T	PFAM response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,PAS_3,PAS_9,Response_reg
k59_191615_1	1121451.DESAM_20709	9.19e-42	159.0	COG0402@1|root,COG0402@2|Bacteria,1MVPA@1224|Proteobacteria,42MJ7@68525|delta/epsilon subdivisions,2WIRS@28221|Deltaproteobacteria,2M8QD@213115|Desulfovibrionales	28221|Deltaproteobacteria	F	PFAM amidohydrolase	-	-	3.5.4.40	ko:K20810	ko00130,ko01110,map00130,map01110	-	R10695	RC00477	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
k59_191615_2	671143.DAMO_2574	1.63e-22	97.1	COG1427@1|root,COG1427@2|Bacteria,2NRPR@2323|unclassified Bacteria	2|Bacteria	S	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnA	-	1.21.98.1,4.2.1.151	ko:K07081,ko:K11782,ko:K11784	ko00130,ko01110,map00130,map01110	-	R08588,R10666	RC02329,RC03232	ko00000,ko00001,ko01000	-	-	-	VitK2_biosynth
k59_237204_1	1156937.MFUM_270075	1.43e-39	139.0	COG5483@1|root,COG5483@2|Bacteria,46TB0@74201|Verrucomicrobia,37H9I@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	S	Protein of unknown function, DUF488	-	-	-	-	-	-	-	-	-	-	-	-	DUF488
k59_123499_1	744872.Spica_2162	2.47e-18	87.8	COG2454@1|root,COG2454@2|Bacteria,2JADQ@203691|Spirochaetes	203691|Spirochaetes	S	Protein of unknown function (DUF434)	-	-	-	-	-	-	-	-	-	-	-	-	DUF434
k59_55370_1	1297742.A176_03875	8.23e-23	95.5	COG0454@1|root,COG0454@2|Bacteria,1QX9F@1224|Proteobacteria,42XG7@68525|delta/epsilon subdivisions,2WTE1@28221|Deltaproteobacteria,2Z0P8@29|Myxococcales	28221|Deltaproteobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_10
k59_199250_1	485916.Dtox_2814	6.44e-25	109.0	COG2202@1|root,COG3437@1|root,COG4191@1|root,COG2202@2|Bacteria,COG3437@2|Bacteria,COG4191@2|Bacteria,1UQJH@1239|Firmicutes,248UM@186801|Clostridia,261WQ@186807|Peptococcaceae	186801|Clostridia	T	HD domain	-	-	-	ko:K07814	-	-	-	-	ko00000,ko02022	-	-	-	GAF_2,HD,HD_5
k59_40113_1	96561.Dole_2074	2.14e-34	128.0	COG1350@1|root,COG1350@2|Bacteria,1N07Y@1224|Proteobacteria,42MPB@68525|delta/epsilon subdivisions,2WJUV@28221|Deltaproteobacteria,2MJ5P@213118|Desulfobacterales	28221|Deltaproteobacteria	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB2	-	4.2.1.20	ko:K06001	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
k59_40113_2	546271.Selsp_0971	4.19e-06	49.7	COG1397@1|root,COG4333@1|root,COG1397@2|Bacteria,COG4333@2|Bacteria,1TQPF@1239|Firmicutes,4H4B7@909932|Negativicutes	909932|Negativicutes	O	ADP-ribosylglycohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	ADP_ribosyl_GH,DUF1643,SseB
k59_55371_1	1232437.KL661988_gene45	1.3e-17	77.0	COG2257@1|root,COG2257@2|Bacteria,1N7F1@1224|Proteobacteria,42VB5@68525|delta/epsilon subdivisions,2WRJD@28221|Deltaproteobacteria,2MKVP@213118|Desulfobacterales	28221|Deltaproteobacteria	S	PFAM FlhB HrpN YscU SpaS Family	-	-	-	ko:K04061	-	-	-	-	ko00000,ko02044	-	-	-	Bac_export_2
k59_85445_1	880072.Desac_0486	1.37e-81	265.0	COG0187@1|root,COG0187@2|Bacteria,1MVKT@1224|Proteobacteria,42M7M@68525|delta/epsilon subdivisions,2WJ9X@28221|Deltaproteobacteria,2MQ5F@213462|Syntrophobacterales	28221|Deltaproteobacteria	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
k59_176532_1	395494.Galf_2311	1.84e-26	110.0	COG3267@1|root,COG3267@2|Bacteria,1MU3G@1224|Proteobacteria,2W9RR@28216|Betaproteobacteria,44WF1@713636|Nitrosomonadales	28216|Betaproteobacteria	U	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22
k59_222106_1	1443665.JACA01000023_gene3744	2.83e-55	181.0	COG1484@1|root,COG1484@2|Bacteria,4NFE0@976|Bacteroidetes,1HYB4@117743|Flavobacteriia,2YJNT@290174|Aquimarina	976|Bacteroidetes	L	IstB-like ATP binding protein	-	-	-	-	-	-	-	-	-	-	-	-	IstB_IS21
k59_85452_1	1121374.KB891586_gene2692	2.42e-25	109.0	COG1033@1|root,COG1033@2|Bacteria,1MUE1@1224|Proteobacteria,1RNWM@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Exporters of the RND superfamily	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
k59_154006_1	945713.IALB_0341	3.83e-130	399.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria	2|Bacteria	G	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)	ppdK	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
k59_168757_1	118005.AWNK01000007_gene565	0.000102	48.5	COG2804@1|root,COG2804@2|Bacteria	2|Bacteria	NU	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB	mshE	-	-	ko:K12276	ko05111,map05111	-	-	-	ko00000,ko00001,ko02044	-	-	-	T2SSE,T2SSE_N
k59_24824_1	1423321.AS29_01850	1.81e-25	103.0	COG0118@1|root,COG0118@2|Bacteria,1TQT0@1239|Firmicutes,4HFXQ@91061|Bacilli,1ZBC4@1386|Bacillus	91061|Bacilli	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR	hisH	GO:0000105,GO:0000107,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	-	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
k59_62862_1	706587.Desti_3761	7.09e-26	106.0	COG0493@1|root,COG1143@1|root,COG0493@2|Bacteria,COG1143@2|Bacteria,1MU2H@1224|Proteobacteria,42PJ7@68525|delta/epsilon subdivisions,2WMEM@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_20,Fer4_7,Pyr_redox_2
k59_119271_2	159087.Daro_2892	5.82e-23	97.8	COG0607@1|root,COG0607@2|Bacteria	2|Bacteria	P	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
k59_135203_1	1121943.KB899993_gene127	2.05e-80	253.0	COG0215@1|root,COG0215@2|Bacteria,1MV8H@1224|Proteobacteria,1RP5K@1236|Gammaproteobacteria,1XH2Z@135619|Oceanospirillales	135619|Oceanospirillales	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	-	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e,tRNA-synt_1g
k59_240694_1	880072.Desac_0395	3.49e-10	60.5	COG0589@1|root,COG0589@2|Bacteria	2|Bacteria	T	AMP binding	usp-3	-	-	-	-	-	-	-	-	-	-	-	Usp
k59_14002_1	335543.Sfum_2564	4.17e-82	257.0	COG1456@1|root,COG1456@2|Bacteria,1R4RE@1224|Proteobacteria,42M89@68525|delta/epsilon subdivisions,2WJVQ@28221|Deltaproteobacteria,2MR7F@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	CO dehydrogenase acetyl-CoA synthase delta subunit	-	-	2.1.1.245	ko:K00197	ko00680,ko00720,ko01120,ko01200,map00680,map00720,map01120,map01200	M00357,M00377,M00422	R09096,R10219,R10243	RC00004,RC00113,RC02977	ko00000,ko00001,ko00002,ko01000	-	-	-	CdhD,FeS
k59_210964_1	28072.Nos7524_3258	7.53e-22	100.0	COG1572@1|root,COG1864@1|root,COG3209@1|root,COG3210@1|root,COG3291@1|root,COG3386@1|root,COG3391@1|root,COG1572@2|Bacteria,COG1864@2|Bacteria,COG3209@2|Bacteria,COG3210@2|Bacteria,COG3291@2|Bacteria,COG3386@2|Bacteria,COG3391@2|Bacteria,1GQ08@1117|Cyanobacteria,1HRMZ@1161|Nostocales	1117|Cyanobacteria	U	PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,Calx-beta,PKD,RHS_repeat
k59_43308_1	177437.HRM2_39480	7.69e-225	629.0	COG3385@1|root,COG3385@2|Bacteria,1RM2A@1224|Proteobacteria,42WE3@68525|delta/epsilon subdivisions,2X6QW@28221|Deltaproteobacteria,2MN97@213118|Desulfobacterales	28221|Deltaproteobacteria	L	Transposase DDE domain group 1	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_4
k59_127457_1	1082933.MEA186_27680	5.93e-35	132.0	COG4974@1|root,COG4974@2|Bacteria,1MXZX@1224|Proteobacteria,2U0B6@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_1,Phage_integrase
k59_4992_1	266264.Rmet_1281	6.39e-90	275.0	COG0309@1|root,COG0309@2|Bacteria,1MVCC@1224|Proteobacteria,2VH3K@28216|Betaproteobacteria,1K3J9@119060|Burkholderiaceae	28216|Betaproteobacteria	O	hydrogenase expression formation protein HypE	hypE	-	-	ko:K04655	-	-	-	-	ko00000	-	-	-	AIRS,AIRS_C
k59_104646_1	401053.AciPR4_4271	1.54e-42	154.0	COG0438@1|root,COG0438@2|Bacteria,3Y58K@57723|Acidobacteria,2JJTZ@204432|Acidobacteriia	204432|Acidobacteriia	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
k59_51092_1	237368.SCABRO_00981	5.24e-54	177.0	COG0546@1|root,COG0546@2|Bacteria,2J0GC@203682|Planctomycetes	203682|Planctomycetes	S	haloacid dehalogenase-like hydrolase	-	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
k59_4998_1	314278.NB231_11694	5.61e-75	244.0	COG1657@1|root,COG1657@2|Bacteria,1MUIP@1224|Proteobacteria,1S118@1236|Gammaproteobacteria,1X0F2@135613|Chromatiales	135613|Chromatiales	I	Squalene-hopene cyclase N-terminal domain	-	-	4.2.1.129,5.4.99.17	ko:K06045	ko00909,ko01110,map00909,map01110	-	R07322,R07323	RC01850,RC01851	ko00000,ko00001,ko01000	-	-	-	SQHop_cyclase_C,SQHop_cyclase_N
k59_203243_1	1121451.DESAM_21249	1.19e-64	216.0	COG0145@1|root,COG0145@2|Bacteria,1MU2Y@1224|Proteobacteria,42NFP@68525|delta/epsilon subdivisions,2WK64@28221|Deltaproteobacteria,2M9T7@213115|Desulfovibrionales	28221|Deltaproteobacteria	EQ	PFAM Hydantoinase oxoprolinase	hyuA	-	3.5.2.14	ko:K01473	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydant_A_N,Hydantoinase_A
k59_119286_1	742818.HMPREF9451_00599	5.39e-43	150.0	COG1974@1|root,COG1974@2|Bacteria,2GMBN@201174|Actinobacteria,4CVG6@84998|Coriobacteriia	84998|Coriobacteriia	K	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair	lexA	-	3.4.21.88	ko:K01356	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	LexA_DNA_bind,Peptidase_S24
k59_20797_1	1037409.BJ6T_66550	7.75e-17	81.3	COG2203@1|root,COG4191@1|root,COG2203@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2TTJ0@28211|Alphaproteobacteria,3JS5D@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HAMP,HATPase_c,HisKA,PAS_7,dCache_1
k59_20797_2	28444.JODQ01000007_gene5417	0.000187	43.9	COG0745@1|root,COG0745@2|Bacteria,2GIZB@201174|Actinobacteria,4EH3M@85012|Streptosporangiales	201174|Actinobacteria	T	Transcriptional regulatory protein, C terminal	mprA	-	-	ko:K07669,ko:K07672	ko02020,map02020	M00460,M00463	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
k59_210993_1	292415.Tbd_0874	5.67e-63	206.0	COG2046@1|root,COG2046@2|Bacteria,1MUQB@1224|Proteobacteria,2VR2T@28216|Betaproteobacteria,1KSBH@119069|Hydrogenophilales	119069|Hydrogenophilales	P	PUA-like domain	-	-	2.7.7.4	ko:K00958	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R04929	RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-sulfurylase,PUA_2
k59_164767_1	338963.Pcar_2643	8.57e-47	163.0	COG1943@1|root,COG1943@2|Bacteria,1MX0E@1224|Proteobacteria,42NN0@68525|delta/epsilon subdivisions,2WM14@28221|Deltaproteobacteria,43UIC@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Bac_DnaA_C,Y1_Tnp
k59_179865_1	1382306.JNIM01000001_gene1463	1.17e-54	185.0	COG3875@1|root,COG3875@2|Bacteria,2G8B3@200795|Chloroflexi	200795|Chloroflexi	S	Domain of unknown function (DUF2088)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2088
k59_119296_1	177437.HRM2_15530	4.19e-69	225.0	COG0668@1|root,COG3064@1|root,COG0668@2|Bacteria,COG3064@2|Bacteria,1N596@1224|Proteobacteria,42Z9C@68525|delta/epsilon subdivisions,2WUFQ@28221|Deltaproteobacteria,2MN3G@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Mechanosensitive ion channel	-	-	-	ko:K03442	-	-	-	-	ko00000,ko02000	1.A.23.2	-	-	MS_channel
k59_240716_1	747365.Thena_1757	1.06e-63	198.0	COG0437@1|root,COG0437@2|Bacteria,1V85Z@1239|Firmicutes,25DIJ@186801|Clostridia,42J57@68295|Thermoanaerobacterales	186801|Clostridia	C	4Fe-4S dicluster domain	-	-	-	ko:K07307	ko00920,map00920	-	R09501	RC02555	ko00000,ko00001,ko02000	5.A.3.3	-	-	Fer4_11,Fer4_4
k59_112230_1	1232410.KI421415_gene3124	9.29e-53	186.0	COG5000@1|root,COG5000@2|Bacteria,1MWKZ@1224|Proteobacteria,42MCN@68525|delta/epsilon subdivisions,2WIYA@28221|Deltaproteobacteria,43SDF@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	PAS domain	ntrY	-	2.7.13.3	ko:K13598	ko02020,map02020	M00498	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4
k59_188364_1	1122138.AQUZ01000013_gene5773	1.77e-10	64.3	2F5KP@1|root,2ZQBG@2|Bacteria,2I8A7@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	SMI1_KNR4
k59_233904_1	1461694.ATO9_09630	2.09e-35	137.0	COG5016@1|root,COG5016@2|Bacteria,1QTTG@1224|Proteobacteria,2TT4W@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Conserved carboxylase domain	-	-	4.1.1.3	ko:K01571	ko00620,ko01100,map00620,map01100	-	R00217	RC00040	ko00000,ko00001,ko01000,ko02000	3.B.1.1.1	-	-	HMGL-like,PYC_OADA
k59_127467_1	1121405.dsmv_3146	4.84e-84	266.0	COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,42M01@68525|delta/epsilon subdivisions,2WJ7M@28221|Deltaproteobacteria,2MHMW@213118|Desulfobacterales	28221|Deltaproteobacteria	V	Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation	msbA	-	-	ko:K06147,ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
k59_179872_1	460265.Mnod_5186	2.52e-67	214.0	COG0031@1|root,COG0031@2|Bacteria,1MUBE@1224|Proteobacteria,2TS33@28211|Alphaproteobacteria,1JQTK@119045|Methylobacteriaceae	28211|Alphaproteobacteria	E	Cysteine synthase A	cysK	-	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
k59_104665_1	1499967.BAYZ01000009_gene5393	1.38e-104	314.0	COG2718@1|root,COG2718@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF444)	yhbH	-	-	ko:K09786	-	-	-	-	ko00000	-	-	-	DUF444,Haem_oxygenas_2
k59_119299_1	439235.Dalk_0581	8.46e-73	234.0	COG4671@1|root,COG4671@2|Bacteria,1NE6T@1224|Proteobacteria,42M07@68525|delta/epsilon subdivisions,2WJA3@28221|Deltaproteobacteria,2MHTF@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Glycosyltransferase family 28 C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tran_28_C
k59_225550_1	1167006.UWK_01521	2.2e-15	80.1	28WPZ@1|root,2ZIPP@2|Bacteria,1RA62@1224|Proteobacteria,42QRN@68525|delta/epsilon subdivisions,2WN0T@28221|Deltaproteobacteria,2MJGA@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_89381_1	658086.HMPREF0994_01534	1.49e-07	59.3	COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,247VG@186801|Clostridia,27I92@186928|unclassified Lachnospiraceae	186801|Clostridia	T	His Kinase A (phospho-acceptor) domain	phoR	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4,sCache_like
k59_179874_2	756067.MicvaDRAFT_1231	1.75e-109	335.0	COG1506@1|root,COG1506@2|Bacteria,1G200@1117|Cyanobacteria,1H8T3@1150|Oscillatoriales	1117|Cyanobacteria	E	PFAM Prolyl oligopeptidase family	dap2	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
k59_149491_2	1499967.BAYZ01000113_gene2935	1.79e-73	223.0	COG0080@1|root,COG0080@2|Bacteria,2NP7W@2323|unclassified Bacteria	2|Bacteria	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors	rplK	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0006950,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0010467,GO:0015934,GO:0015968,GO:0016043,GO:0019538,GO:0019843,GO:0022411,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0032984,GO:0032991,GO:0033554,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0042594,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0051716,GO:0065003,GO:0070925,GO:0071496,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02867	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L11,Ribosomal_L11_N
k59_179881_1	525904.Tter_2465	1.18e-31	127.0	COG2217@1|root,COG2217@2|Bacteria,2NNPJ@2323|unclassified Bacteria	2|Bacteria	P	E1-E2 ATPase	-	-	3.6.3.4	ko:K01533,ko:K12955	-	-	R00086	RC00002	ko00000,ko01000	3.A.3.24,3.A.3.5	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,HMA,Hydrolase
k59_157706_1	290397.Adeh_1975	2.32e-52	172.0	COG0290@1|root,COG0290@2|Bacteria,1RDD2@1224|Proteobacteria,42RHA@68525|delta/epsilon subdivisions,2WNQW@28221|Deltaproteobacteria,2YVAJ@29|Myxococcales	28221|Deltaproteobacteria	J	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins	infC	GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008	-	ko:K02520	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	IF3_C,IF3_N
k59_96992_1	335543.Sfum_0687	7.61e-38	149.0	COG1413@1|root,COG1413@2|Bacteria,1P1H4@1224|Proteobacteria,431VX@68525|delta/epsilon subdivisions,2WWU3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_43336_1	706587.Desti_4488	7.69e-25	103.0	COG1641@1|root,COG1641@2|Bacteria,1MUKU@1224|Proteobacteria,42MHQ@68525|delta/epsilon subdivisions,2WJAC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Belongs to the LarC family	-	-	4.99.1.12	ko:K09121	-	-	-	-	ko00000,ko01000	-	-	-	DUF111
k59_43336_2	485915.Dret_0175	5.09e-15	74.3	COG2414@1|root,COG2414@2|Bacteria,1MWBB@1224|Proteobacteria,42MZJ@68525|delta/epsilon subdivisions,2WJK1@28221|Deltaproteobacteria,2M804@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	PFAM Aldehyde ferredoxin oxidoreductase	-	-	1.2.7.5	ko:K03738	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00309	R08571	RC00242	ko00000,ko00001,ko00002,ko01000	-	-	-	AFOR_C,AFOR_N
k59_43340_1	879212.DespoDRAFT_03644	9.52e-55	182.0	COG2264@1|root,COG2264@2|Bacteria,1MUPC@1224|Proteobacteria,42NSS@68525|delta/epsilon subdivisions,2WIVV@28221|Deltaproteobacteria,2MHQ2@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Methylates ribosomal protein L11	prmA	-	-	ko:K02687	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PrmA
k59_179897_1	177437.HRM2_48070	4.39e-51	175.0	COG0582@1|root,COG0582@2|Bacteria,1MVZB@1224|Proteobacteria,42T3Q@68525|delta/epsilon subdivisions,2WPUB@28221|Deltaproteobacteria,2MKDP@213118|Desulfobacterales	28221|Deltaproteobacteria	L	Phage integrase, N-terminal SAM-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
k59_179901_1	335543.Sfum_2756	1.34e-40	152.0	COG0707@1|root,COG1413@1|root,COG0707@2|Bacteria,COG1413@2|Bacteria,1MVIB@1224|Proteobacteria,42ME1@68525|delta/epsilon subdivisions,2WJNY@28221|Deltaproteobacteria,2MRPC@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
k59_225574_1	469382.Hbor_00810	0.000312	48.9	COG2203@1|root,arCOG02329@1|root,arCOG02387@1|root,arCOG02329@2157|Archaea,arCOG02369@2157|Archaea,arCOG02387@2157|Archaea,2Y149@28890|Euryarchaeota,240V2@183963|Halobacteria	183963|Halobacteria	T	COG0784 FOG CheY-like receiver	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_3,Response_reg
k59_66275_1	228410.NE1093	2.05e-52	181.0	COG3666@1|root,COG3666@2|Bacteria,1N3QR@1224|Proteobacteria,2WADG@28216|Betaproteobacteria,374FC@32003|Nitrosomonadales	28216|Betaproteobacteria	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF772
k59_28156_1	667014.Thein_2095	2.42e-107	318.0	COG0052@1|root,COG0052@2|Bacteria,2GHHG@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	J	Belongs to the universal ribosomal protein uS2 family	rpsB	-	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
k59_127498_1	1122929.KB908216_gene2224	2.69e-05	46.2	COG0621@1|root,COG0621@2|Bacteria,1MURS@1224|Proteobacteria,2TQN6@28211|Alphaproteobacteria	28211|Alphaproteobacteria	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
k59_127498_2	177439.DP2226	7.02e-19	89.7	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,42M51@68525|delta/epsilon subdivisions,2WIPP@28221|Deltaproteobacteria,2MI4H@213118|Desulfobacterales	28221|Deltaproteobacteria	NU	TIGRFAM type IV-A pilus assembly ATPase PilB	pilB	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE,T2SSE_N,cNMP_binding
k59_203272_1	436308.Nmar_0083	1.08e-25	107.0	COG1903@1|root,arCOG04383@2157|Archaea,41S70@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A	cbiD	-	2.1.1.195	ko:K02188	ko00860,ko01100,map00860,map01100	-	R07773	RC00003,RC02051	ko00000,ko00001,ko01000	-	-	-	CbiD
k59_218108_1	1121451.DESAM_23070	1.77e-73	244.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42NFY@68525|delta/epsilon subdivisions,2WKC0@28221|Deltaproteobacteria,2M7TX@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	PFAM ATP-binding region ATPase domain protein	-	-	2.7.13.3	ko:K10819	-	-	-	-	ko00000,ko01000	-	-	-	HATPase_c,HisKA,PAS_8,PAS_9,sCache_3_2
k59_211055_1	400682.PAC_15728378	3.38e-10	67.4	COG5021@1|root,KOG0941@2759|Eukaryota,38BET@33154|Opisthokonta,3BB1I@33208|Metazoa	33208|Metazoa	O	HECT and RLD domain containing E3 ubiquitin protein ligase	HERC4	GO:0000003,GO:0000209,GO:0001650,GO:0002682,GO:0002684,GO:0003674,GO:0003824,GO:0004842,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005730,GO:0005737,GO:0005829,GO:0006464,GO:0006508,GO:0006511,GO:0006807,GO:0007276,GO:0007283,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009966,GO:0009967,GO:0009968,GO:0009987,GO:0010646,GO:0010647,GO:0010648,GO:0016567,GO:0016740,GO:0019538,GO:0019787,GO:0019941,GO:0019953,GO:0022414,GO:0023051,GO:0023056,GO:0023057,GO:0030163,GO:0031347,GO:0031349,GO:0031974,GO:0031981,GO:0032446,GO:0032501,GO:0032504,GO:0032879,GO:0032880,GO:0034121,GO:0034123,GO:0034124,GO:0034126,GO:0035330,GO:0035331,GO:0036211,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044452,GO:0044464,GO:0044703,GO:0045088,GO:0045089,GO:0048232,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048584,GO:0048585,GO:0048609,GO:0050776,GO:0050778,GO:0050789,GO:0050794,GO:0051603,GO:0051704,GO:0051865,GO:0060341,GO:0061630,GO:0061659,GO:0065007,GO:0070013,GO:0070647,GO:0071704,GO:0080134,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1902531,GO:1902532,GO:1903076,GO:1903078,GO:1903827,GO:1903829,GO:1904375,GO:1904377,GO:1905475,GO:1905477	2.3.2.26	ko:K10614,ko:K10615	ko04120,map04120	-	-	-	ko00000,ko00001,ko01000,ko04121	-	-	-	HECT,RCC1
k59_240756_1	1121434.AULY01000010_gene2360	1.32e-72	230.0	COG0614@1|root,COG0614@2|Bacteria,1MWVF@1224|Proteobacteria,42PQA@68525|delta/epsilon subdivisions,2WNUY@28221|Deltaproteobacteria,2M887@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	PFAM periplasmic binding protein	-	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
k59_240756_2	207559.Dde_3105	3.54e-28	109.0	COG1120@1|root,COG1120@2|Bacteria,1MUNG@1224|Proteobacteria,42P8N@68525|delta/epsilon subdivisions,2WIWA@28221|Deltaproteobacteria,2M9KN@213115|Desulfovibrionales	28221|Deltaproteobacteria	HP	PFAM ABC transporter related	-	-	3.6.3.34	ko:K02013	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	ABC_tran
k59_89417_1	526222.Desal_3047	1.43e-64	222.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2WJN5@28221|Deltaproteobacteria,2MG2T@213115|Desulfovibrionales	28221|Deltaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_36510_1	404589.Anae109_1288	1.38e-72	222.0	COG0377@1|root,COG0377@2|Bacteria,1MUI2@1224|Proteobacteria,42MDJ@68525|delta/epsilon subdivisions,2WNNV@28221|Deltaproteobacteria,2Z08H@29|Myxococcales	28221|Deltaproteobacteria	C	Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoB	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
k59_164806_1	710111.FraQA3DRAFT_3349	0.000242	45.8	COG0647@1|root,COG0647@2|Bacteria,2GJG6@201174|Actinobacteria	201174|Actinobacteria	G	Belongs to the HAD-like hydrolase superfamily	-	-	-	ko:K02566	-	-	-	-	ko00000	-	-	-	Hydrolase_6,Hydrolase_like
k59_164806_2	583355.Caka_0770	1.35e-64	210.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1,Glycos_transf_2
k59_28164_1	1265505.ATUG01000002_gene2122	3.99e-159	451.0	COG0189@1|root,COG0189@2|Bacteria,1MX62@1224|Proteobacteria,42NIA@68525|delta/epsilon subdivisions,2WKAY@28221|Deltaproteobacteria,2MMEB@213118|Desulfobacterales	28221|Deltaproteobacteria	HJ	Prokaryotic glutathione synthetase, ATP-grasp domain	rimK	-	-	ko:K05844	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	RimK,TrkA_C
k59_225589_1	459495.SPLC1_S171240	1.2e-17	84.3	COG3735@1|root,COG3735@2|Bacteria,1G6DE@1117|Cyanobacteria	1117|Cyanobacteria	S	TraB family	-	-	-	ko:K09973	-	-	-	-	ko00000	-	-	-	TraB
k59_59885_1	395964.KE386496_gene784	1.93e-07	55.5	COG0741@1|root,COG0741@2|Bacteria,1RD96@1224|Proteobacteria,2U8C8@28211|Alphaproteobacteria,3NB24@45404|Beijerinckiaceae	28211|Alphaproteobacteria	M	Transglycosylase SLT domain	slt	-	-	-	-	-	-	-	-	-	-	-	SLT
k59_180450_1	1232410.KI421425_gene1575	2.15e-12	69.7	2AKQ6@1|root,31BGX@2|Bacteria,1RCS3@1224|Proteobacteria,43CF4@68525|delta/epsilon subdivisions,2WP3G@28221|Deltaproteobacteria,43SKD@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF3426)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3426,zinc_ribbon_4
k59_180450_2	398767.Glov_0875	2.53e-48	167.0	COG1226@1|root,COG1226@2|Bacteria,1MU1R@1224|Proteobacteria,42MW6@68525|delta/epsilon subdivisions,2WIYU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Ion transport 2 domain protein	-	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans_2,TrkA_C,TrkA_N
k59_143368_1	1040989.AWZU01000112_gene4443	7.79e-104	310.0	COG2801@1|root,COG2801@2|Bacteria,1MVXQ@1224|Proteobacteria,2U0FG@28211|Alphaproteobacteria,3JX5H@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	L	COG2801 Transposase and inactivated derivatives	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve
k59_165261_1	555779.Dthio_PD3181	6.7e-24	101.0	2CC7H@1|root,32RJ0@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_74758_1	795359.TOPB45_1204	7.91e-46	160.0	COG5557@1|root,COG5557@2|Bacteria,2GHG7@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	C	Polysulphide reductase, NrfD	-	-	-	ko:K00185	-	-	-	-	ko00000	5.A.3	-	-	NrfD
k59_234409_1	1250006.JHZZ01000001_gene976	3.19e-42	152.0	COG3039@1|root,COG3039@2|Bacteria,4NGW9@976|Bacteroidetes,1I40S@117743|Flavobacteriia	976|Bacteroidetes	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_2,DUF772
k59_105327_1	96561.Dole_1446	1.13e-57	204.0	COG0458@1|root,COG0458@2|Bacteria,1NPMZ@1224|Proteobacteria,42NF3@68525|delta/epsilon subdivisions,2WM4C@28221|Deltaproteobacteria,2MIQ1@213118|Desulfobacterales	28221|Deltaproteobacteria	F	ATP-grasp domain	-	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_0661	CPSase_L_D2,CPSase_L_D3,MGS
k59_135865_1	335543.Sfum_3774	2.29e-18	86.7	COG3164@1|root,COG3164@2|Bacteria,1NSC1@1224|Proteobacteria,43CFQ@68525|delta/epsilon subdivisions,2X7QS@28221|Deltaproteobacteria,2MQQM@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	AsmA-like C-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	AsmA_2,DUF3971
k59_59893_1	983545.Glaag_3147	6.36e-26	110.0	COG0750@1|root,COG0750@2|Bacteria,1MU91@1224|Proteobacteria,1RMIX@1236|Gammaproteobacteria,46453@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	zinc metalloprotease	rseP	GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006355,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016020,GO:0016021,GO:0016787,GO:0019219,GO:0019222,GO:0019538,GO:0031224,GO:0031226,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0043170,GO:0043856,GO:0044238,GO:0044425,GO:0044459,GO:0044464,GO:0045152,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:0140110,GO:1901564,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_M50
k59_180463_1	1121405.dsmv_3476	1.16e-118	363.0	COG0495@1|root,COG0495@2|Bacteria,1MV47@1224|Proteobacteria,42MRQ@68525|delta/epsilon subdivisions,2WJ3E@28221|Deltaproteobacteria,2MJ6A@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	iAF987.Gmet_2300	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
k59_211297_1	933262.AXAM01000038_gene896	2.19e-68	214.0	COG1235@1|root,COG1235@2|Bacteria,1NW4Z@1224|Proteobacteria,42PTI@68525|delta/epsilon subdivisions,2WIWT@28221|Deltaproteobacteria,2MIKY@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
k59_97207_1	755178.Cyan10605_2092	1.27e-07	55.1	COG3225@1|root,COG3225@2|Bacteria,1G0JN@1117|Cyanobacteria	1117|Cyanobacteria	N	transport system involved in gliding motility, auxiliary component	-	-	-	-	-	-	-	-	-	-	-	-	ABC_transp_aux
k59_234218_1	46234.ANA_C20259	0.000109	50.1	COG0739@1|root,COG0739@2|Bacteria,1G42A@1117|Cyanobacteria,1HKFF@1161|Nostocales	1117|Cyanobacteria	M	Peptidase family M23	-	-	3.4.24.75	ko:K08259	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M23
k59_14381_1	574375.BAGA_03890	1e-18	89.0	COG0373@1|root,COG0373@2|Bacteria,1TQN9@1239|Firmicutes,4HAVC@91061|Bacilli,1ZBER@1386|Bacillus	91061|Bacilli	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS08420	GlutR_N,GlutR_dimer,Shikimate_DH
k59_149746_1	439235.Dalk_3670	8.34e-112	328.0	COG0559@1|root,COG0559@2|Bacteria,1MU25@1224|Proteobacteria,42NME@68525|delta/epsilon subdivisions,2WJ4A@28221|Deltaproteobacteria,2MJ1K@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Branched-chain amino acid transport system / permease component	livH	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
k59_149746_2	439235.Dalk_3671	5.59e-68	221.0	COG4177@1|root,COG4177@2|Bacteria,1MV66@1224|Proteobacteria,42M19@68525|delta/epsilon subdivisions,2WIYH@28221|Deltaproteobacteria,2MI08@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Branched-chain amino acid transport system / permease component	livM	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
k59_21109_1	1121405.dsmv_1688	4.04e-27	106.0	COG2185@1|root,COG2185@2|Bacteria,1NXT9@1224|Proteobacteria,430CW@68525|delta/epsilon subdivisions,2WVX6@28221|Deltaproteobacteria,2MNQ9@213118|Desulfobacterales	28221|Deltaproteobacteria	I	B12 binding domain	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding
k59_173059_2	1519464.HY22_12830	2.18e-05	52.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
k59_66533_1	1304885.AUEY01000003_gene542	7.94e-53	182.0	COG0130@1|root,COG0130@2|Bacteria,1MV0N@1224|Proteobacteria,42MU5@68525|delta/epsilon subdivisions,2WKWY@28221|Deltaproteobacteria,2MJFR@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481	5.4.99.25	ko:K03177	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruB_C,TruB_C_2,TruB_N
k59_135587_1	558152.IQ37_02135	4.72e-64	210.0	COG3666@1|root,COG3666@2|Bacteria,4NEDD@976|Bacteroidetes,1I0PW@117743|Flavobacteriia,3ZSET@59732|Chryseobacterium	976|Bacteroidetes	L	Transposase domain (DUF772)	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_6,DUF772
k59_188645_1	637389.Acaty_c1033	1.38e-43	147.0	COG3547@1|root,COG3547@2|Bacteria,1MXKJ@1224|Proteobacteria,1RSCP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_82298_1	1205908.AKXW01000108_gene1253	2.41e-104	318.0	COG2985@1|root,COG2985@2|Bacteria,1MUVM@1224|Proteobacteria,1RQ47@1236|Gammaproteobacteria,1XUJ4@135623|Vibrionales	135623|Vibrionales	S	Predicted Permease Membrane Region	-	-	-	ko:K07085	-	-	-	-	ko00000	2.A.81	-	-	Asp-Al_Ex
k59_143084_1	1429046.RR21198_0294	2.86e-47	163.0	COG1652@1|root,COG1652@2|Bacteria,2IAAU@201174|Actinobacteria,4G82J@85025|Nocardiaceae	201174|Actinobacteria	S	PFAM Peptidoglycan-binding	-	-	-	-	-	-	-	-	-	-	-	-	LysM
k59_28813_1	1121403.AUCV01000012_gene4110	1.36e-54	196.0	COG0308@1|root,COG3016@1|root,COG0308@2|Bacteria,COG3016@2|Bacteria,1MX1I@1224|Proteobacteria,42U2R@68525|delta/epsilon subdivisions,2WQAR@28221|Deltaproteobacteria,2MPWA@213118|Desulfobacterales	28221|Deltaproteobacteria	EO	Haem-binding uptake, Tiki superfamily, ChaN	-	-	-	-	-	-	-	-	-	-	-	-	Cofac_haem_bdg,PDZ_2,Peptidase_M1
k59_66952_1	272134.KB731325_gene566	2.93e-70	229.0	COG4467@1|root,COG4467@2|Bacteria	2|Bacteria	L	Involved in initiation control of chromosome replication	-	-	-	ko:K07484	-	-	-	-	ko00000	-	-	-	DDE_Tnp_IS66,zf-IS66
k59_82721_1	331869.BAL199_14507	2.5e-37	135.0	COG3473@1|root,COG3473@2|Bacteria,1RB05@1224|Proteobacteria,2U5DB@28211|Alphaproteobacteria,4BTBP@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	Q	Asp Glu Hydantoin racemase family protein	-	-	5.2.1.1	ko:K01799	ko00650,ko00760,ko01120,map00650,map00760,map01120	M00622	R01087	RC00448	ko00000,ko00001,ko00002,ko01000	-	-	-	Asp_Glu_race
k59_135974_1	555779.Dthio_PD3202	8.02e-60	185.0	COG3093@1|root,COG3093@2|Bacteria,1N76J@1224|Proteobacteria,42VQB@68525|delta/epsilon subdivisions,2WRF4@28221|Deltaproteobacteria,2MD69@213115|Desulfovibrionales	28221|Deltaproteobacteria	K	TIGRFAM Addiction module antidote protein, HigA	-	-	-	ko:K21498	-	-	-	-	ko00000,ko02048	-	-	-	HTH_3
k59_51774_1	351160.RCIX1330	5.02e-16	80.5	COG1082@1|root,arCOG01895@2157|Archaea	2157|Archaea	G	PFAM Xylose isomerase domain protein TIM barrel	-	-	5.1.3.30,5.1.3.31	ko:K18910	-	-	R10817,R10818	RC03111,RC03283	ko00000,ko01000	-	-	-	AP_endonuc_2
k59_150182_1	96561.Dole_2243	9.6e-67	215.0	COG1104@1|root,COG1104@2|Bacteria,1MU1C@1224|Proteobacteria,42M5V@68525|delta/epsilon subdivisions,2WIR6@28221|Deltaproteobacteria,2MHV8@213118|Desulfobacterales	28221|Deltaproteobacteria	H	aminotransferase class V	-	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
k59_120008_1	338966.Ppro_3094	1.22e-54	186.0	COG0621@1|root,COG0621@2|Bacteria,1MU7N@1224|Proteobacteria,42MRJ@68525|delta/epsilon subdivisions,2WITA@28221|Deltaproteobacteria,43TZ3@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12	rimO	-	2.8.4.4	ko:K14441	-	-	R10652	RC00003,RC03217	ko00000,ko01000,ko03009	-	-	-	Radical_SAM,TRAM,UPF0004
k59_90062_1	665571.STHERM_c02830	2.13e-88	273.0	COG0174@1|root,COG0174@2|Bacteria,2J6JS@203691|Spirochaetes	203691|Spirochaetes	E	PFAM Glutamine synthetase, catalytic domain	-	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
k59_28824_1	335543.Sfum_4070	1.32e-108	324.0	COG0559@1|root,COG0559@2|Bacteria,1MU25@1224|Proteobacteria,42MKP@68525|delta/epsilon subdivisions,2WJU9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
k59_128090_1	323848.Nmul_A2478	3.53e-19	88.6	COG1678@1|root,COG1678@2|Bacteria,1RCXM@1224|Proteobacteria,2VJQA@28216|Betaproteobacteria,372DD@32003|Nitrosomonadales	28216|Betaproteobacteria	K	Belongs to the UPF0301 (AlgH) family	algH	-	-	ko:K07735	-	-	-	-	ko00000,ko03000	-	-	-	DUF179
k59_51785_1	439235.Dalk_4371	8.72e-40	139.0	COG3640@1|root,COG3640@2|Bacteria,1RB02@1224|Proteobacteria,42NBP@68525|delta/epsilon subdivisions,2WKS7@28221|Deltaproteobacteria,2MJA2@213118|Desulfobacterales	28221|Deltaproteobacteria	D	PFAM Cobyrinic acid ac-diamide synthase	cooC	-	-	ko:K07321	-	-	-	-	ko00000	-	-	-	CbiA
k59_37176_1	1120746.CCNL01000017_gene2748	2.7e-08	57.8	COG4177@1|root,COG4177@2|Bacteria	2|Bacteria	E	L-phenylalanine transmembrane transporter activity	MA20_22605	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
k59_37176_2	880072.Desac_0869	3.23e-13	68.9	COG0559@1|root,COG0559@2|Bacteria,1N5XH@1224|Proteobacteria,42PN7@68525|delta/epsilon subdivisions,2WIRP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
k59_226338_1	194867.ALBQ01000060_gene3404	1.1e-25	106.0	COG3666@1|root,COG3666@2|Bacteria,1N3QR@1224|Proteobacteria,2TRXG@28211|Alphaproteobacteria,2K252@204457|Sphingomonadales	204457|Sphingomonadales	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_6,DUF772
k59_158387_1	331678.Cphamn1_1145	3.2e-26	108.0	COG4974@1|root,COG4974@2|Bacteria	2|Bacteria	L	Belongs to the 'phage' integrase family	int	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_4,Phage_integrase
k59_234552_2	1353537.TP2_14975	3.34e-26	101.0	COG0509@1|root,COG0509@2|Bacteria,1RGV7@1224|Proteobacteria,2U9BY@28211|Alphaproteobacteria,2XNBY@285107|Thioclava	28211|Alphaproteobacteria	E	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein	gcvH	-	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	-	GCV_H
k59_44086_1	1125863.JAFN01000001_gene2454	8.8e-61	197.0	COG1045@1|root,COG1045@2|Bacteria,1MVFX@1224|Proteobacteria,42MND@68525|delta/epsilon subdivisions,2WJC3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	serine O-acetyltransferase	cysE	-	2.3.1.30	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	M00021	R00586	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,SATase_N
k59_37198_1	335543.Sfum_2408	1.45e-39	140.0	COG0702@1|root,COG0702@2|Bacteria,1PDTN@1224|Proteobacteria,42M8X@68525|delta/epsilon subdivisions,2WJ5J@28221|Deltaproteobacteria	28221|Deltaproteobacteria	GM	PFAM NAD-dependent epimerase dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	DUF2867,NAD_binding_10
k59_234555_1	879212.DespoDRAFT_00143	7.93e-15	73.6	COG0309@1|root,COG0309@2|Bacteria,1MVCC@1224|Proteobacteria,42M3M@68525|delta/epsilon subdivisions,2WJ8B@28221|Deltaproteobacteria,2MHUA@213118|Desulfobacterales	28221|Deltaproteobacteria	O	hydrogenase expression formation protein HypE	hypE	-	-	ko:K04655	-	-	-	-	ko00000	-	-	-	AIRS,AIRS_C
k59_234555_2	1265505.ATUG01000001_gene3999	9.78e-83	256.0	COG0409@1|root,COG0409@2|Bacteria,1MU1F@1224|Proteobacteria,42M6R@68525|delta/epsilon subdivisions,2WJDQ@28221|Deltaproteobacteria,2MIT3@213118|Desulfobacterales	28221|Deltaproteobacteria	O	hydrogenase expression formation protein HypD	hypD	-	-	ko:K04654	-	-	-	-	ko00000	-	-	iAF987.Gmet_0117	HypD
k59_60039_1	1125863.JAFN01000001_gene1961	1.47e-60	202.0	COG1030@1|root,COG1030@2|Bacteria,1MUJN@1224|Proteobacteria,42MWM@68525|delta/epsilon subdivisions,2WK3H@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Membrane-bound serine protease (ClpP class)	nfeD	-	-	ko:K07403	-	-	-	-	ko00000	-	-	-	CLP_protease,NfeD,SDH_sah
k59_60039_2	485915.Dret_1024	1.39e-14	72.4	COG0330@1|root,COG0330@2|Bacteria,1MUM8@1224|Proteobacteria,42NX0@68525|delta/epsilon subdivisions,2WISZ@28221|Deltaproteobacteria,2M97G@213115|Desulfovibrionales	28221|Deltaproteobacteria	O	PFAM Band 7 protein	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
k59_241354_1	679935.Alfi_0751	5.61e-46	168.0	2A774@1|root,30W38@2|Bacteria,4NPP9@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_44092_1	96561.Dole_0545	3.92e-16	79.7	COG0330@1|root,COG0330@2|Bacteria,1MUM2@1224|Proteobacteria,42NUT@68525|delta/epsilon subdivisions,2WKQX@28221|Deltaproteobacteria,2MI5I@213118|Desulfobacterales	28221|Deltaproteobacteria	O	HflC and HflK could encode or regulate a protease	hflK	-	-	ko:K04088	-	M00742	-	-	ko00000,ko00002,ko01000	-	-	-	Band_7
k59_44092_2	1056820.KB900633_gene2080	1.88e-18	84.0	COG0330@1|root,COG0330@2|Bacteria,1MV7R@1224|Proteobacteria,1RM8Z@1236|Gammaproteobacteria,2PMU8@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	O	prohibitin homologues	hflC	-	-	ko:K04087	-	M00742	-	-	ko00000,ko00002,ko01000	-	-	-	Band_7
k59_150226_1	1121405.dsmv_0458	3.64e-60	205.0	COG1450@1|root,COG1450@2|Bacteria,1MUUA@1224|Proteobacteria,42M9I@68525|delta/epsilon subdivisions,2WK1H@28221|Deltaproteobacteria,2MIEH@213118|Desulfobacterales	28221|Deltaproteobacteria	NU	type II and III secretion system protein	gspD	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	Secretin,Secretin_N
k59_195611_1	96561.Dole_1876	1.52e-64	218.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,42M2R@68525|delta/epsilon subdivisions,2WJ4J@28221|Deltaproteobacteria,2MHN2@213118|Desulfobacterales	28221|Deltaproteobacteria	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
k59_5680_1	1121405.dsmv_2311	4.9e-29	113.0	COG2208@1|root,COG3437@1|root,COG2208@2|Bacteria,COG3437@2|Bacteria,1N4K5@1224|Proteobacteria,42T2F@68525|delta/epsilon subdivisions,2WPGM@28221|Deltaproteobacteria,2MKRM@213118|Desulfobacterales	28221|Deltaproteobacteria	KT	Sigma factor PP2C-like phosphatases	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	Response_reg,SpoIIE
k59_5680_2	1121447.JONL01000003_gene3227	8.37e-25	97.4	COG1366@1|root,COG1366@2|Bacteria,1N7D9@1224|Proteobacteria,42V1I@68525|delta/epsilon subdivisions,2WRH0@28221|Deltaproteobacteria,2MD3V@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	transporter antisigma-factor antagonist STAS	-	-	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS
k59_241355_1	436114.SYO3AOP1_0394	4.33e-24	102.0	COG0664@1|root,COG0664@2|Bacteria,2G4H3@200783|Aquificae	200783|Aquificae	K	Transcriptional regulator, Crp Fnr family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Crp_2,cNMP_binding
k59_195614_1	1459636.NTE_03123	5.94e-50	175.0	COG0459@1|root,arCOG01257@2157|Archaea,41SDG@651137|Thaumarchaeota	651137|Thaumarchaeota	O	PFAM TCP-1 cpn60 chaperonin family	-	-	-	ko:K22447	-	-	-	-	ko00000,ko03110	-	-	-	Cpn60_TCP1
k59_203932_2	4432.XP_010268174.1	1.97e-07	53.1	COG0533@1|root,KOG2708@2759|Eukaryota,37P73@33090|Viridiplantae,3GBBG@35493|Streptophyta	35493|Streptophyta	O	Component of the EKC KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity	GCP2	GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
k59_21543_1	562970.Btus_2732	2.27e-06	55.1	COG0845@1|root,COG0845@2|Bacteria,1V2JZ@1239|Firmicutes,4HIQ8@91061|Bacilli,27A6Z@186823|Alicyclobacillaceae	91061|Bacilli	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
k59_51800_1	1219084.AP014508_gene1056	1.98e-12	75.1	COG1196@1|root,COG1196@2|Bacteria,2GBZE@200918|Thermotogae	200918|Thermotogae	D	Required for chromosome condensation and partitioning	smc	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
k59_150238_1	1125863.JAFN01000001_gene1391	3.73e-40	152.0	COG0265@1|root,COG0308@1|root,COG2234@1|root,COG0265@2|Bacteria,COG0308@2|Bacteria,COG2234@2|Bacteria,1PEPK@1224|Proteobacteria,42NJ8@68525|delta/epsilon subdivisions,2WM57@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	PFAM peptidase M1, membrane alanine aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	iAF987.Gmet_0348	Peptidase_M1
k59_189130_1	1121405.dsmv_2616	4.4e-95	287.0	COG0492@1|root,COG0492@2|Bacteria,1R82E@1224|Proteobacteria,42PSM@68525|delta/epsilon subdivisions,2WJYX@28221|Deltaproteobacteria,2MN1E@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,Pyr_redox_3
k59_165431_1	1121918.ARWE01000001_gene188	5.39e-45	150.0	COG4852@1|root,COG4852@2|Bacteria,1MZHP@1224|Proteobacteria,42TD7@68525|delta/epsilon subdivisions,2WPIH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Predicted membrane protein (DUF2177)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2177
k59_51810_2	65093.PCC7418_0736	5.51e-21	92.8	COG0003@1|root,COG0003@2|Bacteria,1G1UB@1117|Cyanobacteria	1117|Cyanobacteria	P	TIGRFAM arsenite-activated ATPase ArsA	-	-	3.6.3.16	ko:K01551	-	-	-	-	ko00000,ko01000,ko02000	3.A.19.1,3.A.21.1,3.A.4.1	-	-	ArsA_ATPase
k59_113009_1	443144.GM21_2039	1.88e-70	222.0	COG0559@1|root,COG0559@2|Bacteria,1MU25@1224|Proteobacteria,42MKP@68525|delta/epsilon subdivisions,2WJU9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Belongs to the binding-protein-dependent transport system permease family	livH	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
k59_44110_1	1144325.PMI22_06098	3.59e-43	150.0	COG1028@1|root,COG1028@2|Bacteria,1R413@1224|Proteobacteria,1S3TR@1236|Gammaproteobacteria	1236|Gammaproteobacteria	IQ	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
k59_14783_1	985255.APHJ01000021_gene1288	0.000117	49.7	COG0845@1|root,COG0845@2|Bacteria,4NFT4@976|Bacteroidetes,1HYKR@117743|Flavobacteriia,2P6DY@244698|Gillisia	976|Bacteroidetes	M	Barrel-sandwich domain of CusB or HlyD membrane-fusion	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_D23,OEP
k59_44111_1	644968.DFW101_3074	9.24e-43	154.0	COG0745@1|root,COG0745@2|Bacteria,1NE8H@1224|Proteobacteria,42NEH@68525|delta/epsilon subdivisions,2WK1M@28221|Deltaproteobacteria,2M7RK@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	Cytidylate_kin2,Response_reg
k59_226365_1	158189.SpiBuddy_2443	2.73e-50	170.0	COG1172@1|root,COG1172@2|Bacteria,2J781@203691|Spirochaetes	203691|Spirochaetes	G	PFAM Branched-chain amino acid transport system permease component	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
k59_226365_2	158190.SpiGrapes_2787	5.54e-234	654.0	COG1129@1|root,COG1129@2|Bacteria,2J5EN@203691|Spirochaetes	203691|Spirochaetes	P	Part of the ABC transporter complex MglABC involved in galactose methyl galactoside import. Responsible for energy coupling to the transport system	-	-	3.6.3.17	ko:K02056,ko:K10441,ko:K10542,ko:K10548,ko:K17215	ko02010,map02010	M00212,M00214,M00216,M00221,M00593	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2,3.A.1.2.1,3.A.1.2.13,3.A.1.2.19,3.A.1.2.3,3.A.1.2.5	-	-	ABC_tran
k59_82740_1	658086.HMPREF0994_03425	8.03e-20	95.5	COG1123@1|root,COG4172@2|Bacteria,1VRD0@1239|Firmicutes,25ECM@186801|Clostridia,27UGX@186928|unclassified Lachnospiraceae	186801|Clostridia	P	ATPases associated with a variety of cellular activities	-	-	-	ko:K16786,ko:K16787	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ABC_tran,DUF3744
k59_150257_1	388051.AUFE01000166_gene71	2.33e-63	211.0	COG4467@1|root,COG4467@2|Bacteria,1PPMF@1224|Proteobacteria,2VMNS@28216|Betaproteobacteria,1KE34@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Involved in initiation control of chromosome replication	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS66
k59_226369_1	234267.Acid_5892	1.24e-39	145.0	COG1032@1|root,COG1032@2|Bacteria	2|Bacteria	C	radical SAM domain protein	-	-	-	ko:K22318	-	-	-	-	ko00000	-	-	-	B12-binding,Radical_SAM
k59_143604_1	1121405.dsmv_1156	3.44e-55	184.0	COG0463@1|root,COG0463@2|Bacteria,1MXC1@1224|Proteobacteria,42PE4@68525|delta/epsilon subdivisions,2WK83@28221|Deltaproteobacteria,2MPWY@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Glycosyltransferase like family 2	-	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
k59_173454_1	335543.Sfum_2955	2.75e-79	253.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42NWT@68525|delta/epsilon subdivisions,2X5DA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Sigma-54 interaction domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
k59_158419_1	102125.Xen7305DRAFT_00035610	0.000437	43.5	COG0643@1|root,COG0745@1|root,COG2198@1|root,COG0643@2|Bacteria,COG0745@2|Bacteria,COG2198@2|Bacteria,1G0VR@1117|Cyanobacteria,3VHRJ@52604|Pleurocapsales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	ko:K06596	ko02020,ko02025,map02020,map02025	M00507	-	-	ko00000,ko00001,ko00002,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt,Response_reg
k59_158419_2	1232437.KL662050_gene5290	2.26e-52	179.0	COG2204@1|root,COG5000@1|root,COG2204@2|Bacteria,COG5000@2|Bacteria,1RBB9@1224|Proteobacteria,42R73@68525|delta/epsilon subdivisions,2WMPX@28221|Deltaproteobacteria,2MMXA@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Histidine kinase-like ATPases	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,Response_reg
k59_150267_1	1121422.AUMW01000045_gene1210	2.79e-58	201.0	COG0446@1|root,COG1902@1|root,COG0446@2|Bacteria,COG1902@2|Bacteria,1TPM6@1239|Firmicutes,247V1@186801|Clostridia,260YA@186807|Peptococcaceae	186801|Clostridia	C	NADH flavin oxidoreductase NADH oxidase	-	-	1.3.1.34	ko:K00219	-	-	-	-	ko00000,ko01000	-	-	-	Oxidored_FMN,Pyr_redox_2
k59_55738_2	1121451.DESAM_22400	7.54e-19	82.0	COG2259@1|root,COG2259@2|Bacteria,1R0SH@1224|Proteobacteria,43D19@68525|delta/epsilon subdivisions,2X894@28221|Deltaproteobacteria,2MBJN@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	DoxX	-	-	-	-	-	-	-	-	-	-	-	-	MauE
k59_176841_1	1121456.ATVA01000002_gene3167	2.17e-90	272.0	COG0437@1|root,COG0437@2|Bacteria,1MU1B@1224|Proteobacteria,42Q3D@68525|delta/epsilon subdivisions,2WM24@28221|Deltaproteobacteria,2MGKS@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	4Fe-4S dicluster domain	-	-	-	ko:K00124	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001	-	-	-	Fer4_11
k59_131440_1	335543.Sfum_1817	7.97e-222	629.0	COG0661@1|root,COG0661@2|Bacteria,1MU1Z@1224|Proteobacteria,42N87@68525|delta/epsilon subdivisions,2WK1B@28221|Deltaproteobacteria,2MRH3@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	ABC1 family	-	-	-	ko:K03688	-	-	-	-	ko00000	-	-	-	ABC1,RIO1
k59_222488_1	667014.Thein_0393	1.17e-33	131.0	COG2864@1|root,COG2864@2|Bacteria,2GHPY@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	C	Prokaryotic cytochrome b561	-	-	-	-	-	-	-	-	-	-	-	-	Ni_hydr_CYTB
k59_101125_1	439235.Dalk_0086	0.000462	48.5	COG1032@1|root,COG1032@2|Bacteria,1MWR0@1224|Proteobacteria,42YMF@68525|delta/epsilon subdivisions,2WUKB@28221|Deltaproteobacteria,2MN0B@213118|Desulfobacterales	28221|Deltaproteobacteria	C	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
k59_154353_1	96561.Dole_2313	2.81e-60	201.0	COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,42MEA@68525|delta/epsilon subdivisions,2WIW6@28221|Deltaproteobacteria,2MI74@213118|Desulfobacterales	28221|Deltaproteobacteria	KT	Sigma-54 interaction domain	-	-	2.1.1.80	ko:K00575	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	HTH_8,PAS_4,PAS_9,Sigma54_activat
k59_154355_1	234267.Acid_3241	5.38e-15	73.2	COG0020@1|root,COG0020@2|Bacteria,3Y485@57723|Acidobacteria	57723|Acidobacteria	I	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	-	-	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
k59_154355_2	933262.AXAM01000048_gene2588	7.49e-57	189.0	COG4589@1|root,COG4589@2|Bacteria,1R34Q@1224|Proteobacteria,42QTH@68525|delta/epsilon subdivisions,2WQ6V@28221|Deltaproteobacteria,2MIDG@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Belongs to the CDS family	cdsA	-	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
k59_32757_2	1335757.SPICUR_09435	4.38e-37	130.0	COG5002@1|root,COG5002@2|Bacteria,1R2EY@1224|Proteobacteria,1T5PC@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	-	-	-	-	-	-	-	-	-	-	-	-	PAS_9
k59_55748_1	589865.DaAHT2_1663	2.89e-19	84.0	COG1246@1|root,COG1246@2|Bacteria,1RHT7@1224|Proteobacteria,42SGE@68525|delta/epsilon subdivisions,2WP91@28221|Deltaproteobacteria,2MK41@213118|Desulfobacterales	28221|Deltaproteobacteria	E	PFAM GCN5-related N-acetyltransferase	argA	-	2.3.1.1	ko:K00619	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_0946	Acetyltransf_1,Acetyltransf_7
k59_237631_1	589865.DaAHT2_0973	3.9e-95	291.0	COG0743@1|root,COG0743@2|Bacteria,1MU4G@1224|Proteobacteria,42NI1@68525|delta/epsilon subdivisions,2WK14@28221|Deltaproteobacteria,2MIFC@213118|Desulfobacterales	28221|Deltaproteobacteria	I	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)	dxr	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576	1.1.1.267	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05688	RC01452	ko00000,ko00001,ko00002,ko01000	-	-	-	DXPR_C,DXP_redisom_C,DXP_reductoisom
k59_139137_1	931626.Awo_c07520	2.94e-11	63.2	COG1962@1|root,COG1962@2|Bacteria,1UYYD@1239|Firmicutes,24AC2@186801|Clostridia	186801|Clostridia	H	PFAM Tetrahydromethanopterin S-methyltransferase MtrH subunit	-	-	2.1.1.86	ko:K00584	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00357,M00567	R04347	RC00035,RC00113,RC02892	ko00000,ko00001,ko00002,ko01000	-	-	-	MtrH
k59_139137_2	1410608.JNKX01000025_gene523	5.49e-09	60.1	COG0646@1|root,COG5012@1|root,COG0646@2|Bacteria,COG5012@2|Bacteria,4NK9D@976|Bacteroidetes,2FQBD@200643|Bacteroidia,4AMD4@815|Bacteroidaceae	976|Bacteroidetes	E	B12 binding domain	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,B12-binding_2
k59_101136_1	933262.AXAM01000015_gene94	7.04e-73	230.0	COG2414@1|root,COG2414@2|Bacteria,1R76Y@1224|Proteobacteria,42QE3@68525|delta/epsilon subdivisions,2WIIW@28221|Deltaproteobacteria,2MIUU@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Aldehyde ferredoxin oxidoreductase, N-terminal domain	-	-	1.2.7.5	ko:K03738	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00309	R08571	RC00242	ko00000,ko00001,ko00002,ko01000	-	-	-	AFOR_C,AFOR_N
k59_214646_1	1499967.BAYZ01000034_gene1071	4.61e-09	55.5	2E46N@1|root,32Z2M@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_214646_2	679926.Mpet_1150	3.47e-07	55.5	COG0642@1|root,COG2202@1|root,arCOG02385@1|root,arCOG06721@1|root,arCOG02385@2157|Archaea,arCOG06193@2157|Archaea,arCOG06721@2157|Archaea,arCOG06918@2157|Archaea	2157|Archaea	T	Pas domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_8,PAS_9,PocR,Response_reg
k59_47989_1	1381123.AYOD01000001_gene994	1.53e-11	64.3	COG4957@1|root,COG4957@2|Bacteria,1RGUW@1224|Proteobacteria,2U99M@28211|Alphaproteobacteria,43PM3@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	K	Transcriptional regulator	ros	-	-	-	-	-	-	-	-	-	-	-	ROS_MUCR
k59_70592_1	177437.HRM2_22700	9.09e-54	187.0	COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,42M88@68525|delta/epsilon subdivisions,2WIZI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	KT	PFAM sigma-54 factor interaction domain-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,PAS_9,Sigma54_activat
k59_229987_1	1265505.ATUG01000001_gene2927	7.05e-66	218.0	COG1960@1|root,COG1960@2|Bacteria,1MU20@1224|Proteobacteria,42MUH@68525|delta/epsilon subdivisions,2WJ16@28221|Deltaproteobacteria,2MHYV@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Acyl-CoA dehydrogenase N terminal	-	-	-	ko:K09456	-	-	-	-	ko00000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_C,Acyl-CoA_dh_M,Acyl-CoA_dh_N,AcylCoA_DH_N
k59_10200_1	318167.Sfri_0415	2.13e-55	198.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,2Q8ZG@267890|Shewanellaceae	1236|Gammaproteobacteria	T	Two component regulator three Y domain protein	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_3,PAS_9,Reg_prop,Y_Y_Y
k59_139148_1	1121918.ARWE01000001_gene211	5.06e-113	345.0	COG1807@1|root,COG1807@2|Bacteria,1NMIZ@1224|Proteobacteria,42RXF@68525|delta/epsilon subdivisions,2WUR2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
k59_101143_1	643648.Slip_2363	2.05e-105	314.0	COG1924@1|root,COG1924@2|Bacteria,1TPU5@1239|Firmicutes,2481F@186801|Clostridia,42JKR@68298|Syntrophomonadaceae	186801|Clostridia	I	PFAM ATPase BadF BadG BcrA BcrD type	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG
k59_237643_1	697282.Mettu_1209	6.48e-45	155.0	COG1893@1|root,COG1893@2|Bacteria,1MX5M@1224|Proteobacteria,1SZ0M@1236|Gammaproteobacteria,1XDRD@135618|Methylococcales	135618|Methylococcales	H	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid	-	-	1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000	-	-	-	ApbA,ApbA_C
k59_139151_1	335543.Sfum_1380	8.11e-113	335.0	COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,1MU8P@1224|Proteobacteria,42N1C@68525|delta/epsilon subdivisions,2WIP5@28221|Deltaproteobacteria,2MQ94@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	ribBA	-	3.5.4.25,4.1.99.12	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	DHBP_synthase,GTP_cyclohydro2
k59_176848_1	1121918.ARWE01000001_gene2640	1.85e-13	68.9	COG2875@1|root,COG2875@2|Bacteria,1MVYY@1224|Proteobacteria,42P88@68525|delta/epsilon subdivisions,2WMR1@28221|Deltaproteobacteria,43T6V@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	PFAM Uroporphyrin-III C tetrapyrrole (Corrin Porphyrin) methyltransferase	cbiF	-	2.1.1.133,2.1.1.271	ko:K05936	ko00860,ko01100,map00860,map01100	-	R05181,R05810	RC00003,RC01294,RC02049	ko00000,ko00001,ko01000	-	-	-	CbiG_C,CbiG_N,TP_methylase
k59_63255_1	720554.Clocl_3920	5.77e-24	105.0	COG3391@1|root,COG3391@2|Bacteria,1V16K@1239|Firmicutes,24C3C@186801|Clostridia,3WHF2@541000|Ruminococcaceae	186801|Clostridia	U	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	Dockerin_1
k59_10204_1	1121441.AUCX01000005_gene1406	4.45e-34	131.0	COG0857@1|root,COG0857@2|Bacteria,1R6HC@1224|Proteobacteria,42MUU@68525|delta/epsilon subdivisions,2WK3T@28221|Deltaproteobacteria,2M7RH@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	DRTGG domain protein	-	-	-	ko:K06873	-	-	-	-	ko00000	-	-	-	AAA_26,DRTGG
k59_2322_1	1121403.AUCV01000017_gene4543	6.25e-14	77.8	29JMV@1|root,32R9B@2|Bacteria,1MYZI@1224|Proteobacteria,431IJ@68525|delta/epsilon subdivisions,2WX0E@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Protein of unknown function (DUF2860)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2860
k59_55752_1	1121405.dsmv_2881	5.4e-44	147.0	COG5421@1|root,COG5421@2|Bacteria,1R3NX@1224|Proteobacteria,42QDV@68525|delta/epsilon subdivisions,2WIRQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	PFAM transposase, IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_108546_1	1005994.GTGU_01445	1.95e-14	79.0	COG0553@1|root,COG0553@2|Bacteria	2|Bacteria	L	helicase activity	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,SNF2_N
k59_207290_1	1232437.KL662062_gene4228	1.8e-61	203.0	COG0560@1|root,COG3830@1|root,COG0560@2|Bacteria,COG3830@2|Bacteria,1MWA3@1224|Proteobacteria,42NIR@68525|delta/epsilon subdivisions,2WIVQ@28221|Deltaproteobacteria,2MJ7K@213118|Desulfobacterales	28221|Deltaproteobacteria	E	ACT domain	serB	-	3.1.3.3	ko:K01079	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R00582	RC00017	ko00000,ko00001,ko00002,ko01000,ko01009	-	-	-	ACT_6,HAD
k59_146477_1	1121405.dsmv_3653	1.22e-158	449.0	COG0050@1|root,COG0050@2|Bacteria,1MVC0@1224|Proteobacteria,42MWZ@68525|delta/epsilon subdivisions,2WJ2B@28221|Deltaproteobacteria,2MHTQ@213118|Desulfobacterales	28221|Deltaproteobacteria	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
k59_176853_1	1125863.JAFN01000001_gene2814	4.41e-64	202.0	COG1573@1|root,COG1573@2|Bacteria,1PIX8@1224|Proteobacteria,42P41@68525|delta/epsilon subdivisions,2WM40@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	PFAM Uracil-DNA glycosylase superfamily	-	-	-	ko:K10800	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
k59_85788_2	56780.SYN_03818	5.48e-49	162.0	COG0607@1|root,COG0607@2|Bacteria,1RA3A@1224|Proteobacteria,42QNH@68525|delta/epsilon subdivisions,2WMPB@28221|Deltaproteobacteria,2MRWM@213462|Syntrophobacterales	28221|Deltaproteobacteria	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	MauE,Rhodanese
k59_131467_1	1121413.JMKT01000009_gene1799	4.99e-38	141.0	COG0189@1|root,COG0189@2|Bacteria,1MWQA@1224|Proteobacteria,43B1R@68525|delta/epsilon subdivisions,2X6FW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	HJ	RimK domain protein ATP-grasp	-	-	-	ko:K05844	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	RimK
k59_131467_2	335543.Sfum_0364	1.36e-58	201.0	COG1061@1|root,COG1061@2|Bacteria,1QWMJ@1224|Proteobacteria,42NXF@68525|delta/epsilon subdivisions,2WJWA@28221|Deltaproteobacteria,2MRP4@213462|Syntrophobacterales	28221|Deltaproteobacteria	L	Type III restriction enzyme, res subunit	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,ResIII
k59_115988_1	1198232.CYCME_1741	2.83e-19	88.6	COG4591@1|root,COG4591@2|Bacteria,1MVV7@1224|Proteobacteria,1RMP9@1236|Gammaproteobacteria,46067@72273|Thiotrichales	72273|Thiotrichales	M	lipoprotein releasing system, transmembrane protein, LolC E family	-	-	-	ko:K09808	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125	-	-	FtsX,MacB_PCD
k59_115988_2	443143.GM18_0732	3.56e-33	121.0	COG1136@1|root,COG1136@2|Bacteria,1MVSQ@1224|Proteobacteria,42QNS@68525|delta/epsilon subdivisions,2WMSN@28221|Deltaproteobacteria,43SYM@69541|Desulfuromonadales	28221|Deltaproteobacteria	V	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner	lolD	-	-	ko:K09810	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.125	-	-	ABC_tran
k59_2326_1	690850.Desaf_0854	9.15e-58	189.0	COG0639@1|root,COG0639@2|Bacteria,1MUV1@1224|Proteobacteria,42RNB@68525|delta/epsilon subdivisions,2WNEW@28221|Deltaproteobacteria,2MBFV@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	PFAM Metallophosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos_2
k59_191965_1	648885.KB316282_gene273	0.000125	44.7	COG0784@1|root,COG2202@1|root,COG4191@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2TQQ9@28211|Alphaproteobacteria,1JRVE@119045|Methylobacteriaceae	28211|Alphaproteobacteria	T	PFAM response regulator receiver	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,PAS_3,PAS_4,Response_reg,dCache_1
k59_191965_2	269799.Gmet_2563	3.75e-41	151.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,43U5W@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	response regulator	gnfM	-	-	ko:K07712	ko02020,map02020	M00497	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
k59_55761_1	558152.IQ37_17775	1.55e-06	53.1	COG0141@1|root,COG0141@2|Bacteria,4NFPZ@976|Bacteroidetes,1HZ69@117743|Flavobacteriia,3ZQKD@59732|Chryseobacterium	976|Bacteroidetes	E	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine	hisD	GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.23	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01158,R01163,R03012	RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000	-	-	-	Histidinol_dh
k59_124016_1	1121405.dsmv_1700	3.33e-26	105.0	COG2203@1|root,COG2203@2|Bacteria,1R8AK@1224|Proteobacteria,42MTP@68525|delta/epsilon subdivisions,2WIST@28221|Deltaproteobacteria,2MIJP@213118|Desulfobacterales	28221|Deltaproteobacteria	T	GAF domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2
k59_78486_1	710696.Intca_3494	1.17e-143	431.0	COG1321@1|root,COG1321@2|Bacteria,2GN2R@201174|Actinobacteria	201174|Actinobacteria	K	iron dependent repressor	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_40435_1	1121403.AUCV01000002_gene540	4.87e-109	321.0	COG2358@1|root,COG2358@2|Bacteria,1MXW1@1224|Proteobacteria,42MR6@68525|delta/epsilon subdivisions,2WITP@28221|Deltaproteobacteria,2MHTE@213118|Desulfobacterales	28221|Deltaproteobacteria	S	TIGRFAM TRAP transporter solute receptor, TAXI family	-	-	-	ko:K07080	-	-	-	-	ko00000	-	-	-	NMT1_3
k59_70597_1	1123057.P872_20605	3.98e-56	176.0	COG4680@1|root,COG4680@2|Bacteria,4NQ54@976|Bacteroidetes,47SE3@768503|Cytophagia	976|Bacteroidetes	S	HigB_toxin, RelE-like toxic component of a toxin-antitoxin system	-	-	-	ko:K19166	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HigB_toxin
k59_70597_2	385682.AFSL01000082_gene1169	4.02e-32	114.0	COG5499@1|root,COG5499@2|Bacteria,4PK5Q@976|Bacteroidetes,2G1N4@200643|Bacteroidia,3XKXZ@558415|Marinilabiliaceae	976|Bacteroidetes	K	transcription regulator containing HTH domain	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_184579_1	335543.Sfum_1330	2.77e-24	101.0	COG2006@1|root,COG2006@2|Bacteria,1QMGX@1224|Proteobacteria,42PRJ@68525|delta/epsilon subdivisions,2WMFN@28221|Deltaproteobacteria,2MQHV@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF362)	-	-	-	-	-	-	-	-	-	-	-	-	DUF362
k59_184579_2	335543.Sfum_1331	1.02e-68	221.0	2CK1R@1|root,32V4M@2|Bacteria,1NNEB@1224|Proteobacteria,437YS@68525|delta/epsilon subdivisions,2X38Q@28221|Deltaproteobacteria,2MSEY@213462|Syntrophobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_2339_1	1121405.dsmv_0112	6.38e-73	228.0	COG2234@1|root,COG2234@2|Bacteria,1MXZS@1224|Proteobacteria,42S82@68525|delta/epsilon subdivisions,2WNJE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM peptidase M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
k59_169466_1	313628.LNTAR_07926	6.62e-57	190.0	COG3547@1|root,COG3547@2|Bacteria	2|Bacteria	L	Transposase (IS116 IS110 IS902 family)	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_237923_1	1144307.PMI04_04186	1.82e-64	208.0	COG0500@1|root,COG2226@2|Bacteria,1MV7N@1224|Proteobacteria,2TYS2@28211|Alphaproteobacteria,2KEVC@204457|Sphingomonadales	204457|Sphingomonadales	H	RNA cap guanine-N2 methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
k59_78754_2	523850.TON_0048	8.15e-23	96.7	COG0430@1|root,arCOG04125@2157|Archaea,2XT7I@28890|Euryarchaeota,2438J@183968|Thermococci	183968|Thermococci	J	Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP	rtcA	GO:0003674,GO:0003824,GO:0003963,GO:0009975,GO:0016874,GO:0016886,GO:0140098	6.5.1.5	ko:K18105	-	-	-	-	ko00000,ko01000	-	-	-	RTC,RTC_insert
k59_93740_1	694429.Pyrfu_1589	1.93e-06	55.5	COG2414@1|root,arCOG00709@2157|Archaea,2XPTI@28889|Crenarchaeota	28889|Crenarchaeota	C	PFAM Aldehyde ferredoxin oxidoreductase	-	-	1.2.7.5	ko:K03738	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00309	R08571	RC00242	ko00000,ko00001,ko00002,ko01000	-	-	-	AFOR_C,AFOR_N
k59_177188_1	880072.Desac_0499	1.56e-129	379.0	COG1804@1|root,COG1804@2|Bacteria,1MU2K@1224|Proteobacteria,42NP0@68525|delta/epsilon subdivisions,2WVG4@28221|Deltaproteobacteria,2MRQ6@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	L-carnitine dehydratase bile acid-inducible protein F	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
k59_40726_1	236097.ADG881_2167	7.37e-49	173.0	COG0277@1|root,COG0277@2|Bacteria,1MXTV@1224|Proteobacteria,1RRN8@1236|Gammaproteobacteria,1XJ31@135619|Oceanospirillales	135619|Oceanospirillales	C	COG0277 FAD FMN-containing dehydrogenases	-	-	2.5.1.26	ko:K00803	ko00565,ko01100,ko04146,map00565,map01100,map04146	-	R04311	RC00020,RC02886	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
k59_169488_2	187272.Mlg_0586	5.75e-14	69.3	COG0359@1|root,COG0359@2|Bacteria,1RD0R@1224|Proteobacteria,1S3WS@1236|Gammaproteobacteria,1WYD2@135613|Chromatiales	135613|Chromatiales	J	binds to the 23S rRNA	rplI	-	-	ko:K02939	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L9_C,Ribosomal_L9_N
k59_146731_1	880072.Desac_1171	1.02e-85	262.0	COG1077@1|root,COG1077@2|Bacteria,1MUMW@1224|Proteobacteria,42M1J@68525|delta/epsilon subdivisions,2WIQR@28221|Deltaproteobacteria,2MQB1@213462|Syntrophobacterales	28221|Deltaproteobacteria	D	TIGRFAM cell shape determining protein, MreB Mrl family	mreB	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
k59_93748_1	1499967.BAYZ01000048_gene2713	2.18e-79	256.0	COG2103@1|root,COG2103@2|Bacteria,2NP6Y@2323|unclassified Bacteria	2|Bacteria	S	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate	murQ	-	4.2.1.126	ko:K07106	ko00520,ko01100,map00520,map01100	-	R08555	RC00397,RC00746	ko00000,ko00001,ko01000	-	-	-	SIS,SIS_2
k59_162097_2	411154.GFO_1387	1.02e-56	179.0	COG2963@1|root,COG2963@2|Bacteria,4NP72@976|Bacteroidetes,1I2BH@117743|Flavobacteriia	976|Bacteroidetes	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Tnp_1
k59_48201_1	1265505.ATUG01000002_gene1043	2.93e-38	140.0	2C4IE@1|root,30ERP@2|Bacteria,1RG2Q@1224|Proteobacteria,42S4W@68525|delta/epsilon subdivisions,2WND7@28221|Deltaproteobacteria,2MN1X@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_2606_1	177437.HRM2_08090	7.69e-77	250.0	COG0115@1|root,COG0147@1|root,COG0115@2|Bacteria,COG0147@2|Bacteria,1MVBJ@1224|Proteobacteria,42P55@68525|delta/epsilon subdivisions,2WJNC@28221|Deltaproteobacteria,2MHT3@213118|Desulfobacterales	28221|Deltaproteobacteria	EH	Anthranilate synthase component I domain protein	pabB	-	2.6.1.85	ko:K01665	ko00790,map00790	-	R01716	RC00010,RC01418	ko00000,ko00001,ko01000	-	-	-	Aminotran_4,Anth_synt_I_N,Chorismate_bind
k59_48206_1	335543.Sfum_3470	6.02e-51	174.0	COG0773@1|root,COG0773@2|Bacteria,1MV68@1224|Proteobacteria,42MMP@68525|delta/epsilon subdivisions,2WK50@28221|Deltaproteobacteria,2MR03@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	Belongs to the MurCDEF family	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
k59_40732_1	335543.Sfum_0478	6.4e-69	230.0	COG0031@1|root,COG0215@1|root,COG0031@2|Bacteria,COG0215@2|Bacteria,1MUBE@1224|Proteobacteria,42M6M@68525|delta/epsilon subdivisions,2WIQM@28221|Deltaproteobacteria,2MR3Q@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	Pyridoxal-phosphate dependent enzyme	cysM	-	2.5.1.47,6.1.1.16	ko:K01738,ko:K01883,ko:K12339	ko00270,ko00920,ko00970,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map00970,map01100,map01110,map01120,map01130,map01200,map01230	M00021,M00359,M00360	R00897,R03132,R03601,R03650,R04859	RC00020,RC00055,RC00523,RC02814,RC02821,RC02876	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,PALP,tRNA-synt_1e
k59_78769_1	335543.Sfum_1550	4.5e-152	464.0	COG0086@1|root,COG0086@2|Bacteria,1MU3M@1224|Proteobacteria,42NAW@68525|delta/epsilon subdivisions,2WISU@28221|Deltaproteobacteria,2MR5Q@213462|Syntrophobacterales	28221|Deltaproteobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	-	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
k59_33072_2	290397.Adeh_0625	3.98e-17	90.1	COG3852@1|root,COG3852@2|Bacteria,1QVPN@1224|Proteobacteria,42PS3@68525|delta/epsilon subdivisions,2X7MQ@28221|Deltaproteobacteria,2YVCB@29|Myxococcales	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	2.7.13.3	ko:K02668	ko02020,map02020	M00501	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	HATPase_c,HisKA,PAS,PAS_8
k59_185050_1	177437.HRM2_32590	1.53e-51	182.0	COG3225@1|root,COG3225@2|Bacteria,1MY63@1224|Proteobacteria,42N95@68525|delta/epsilon subdivisions,2WJ0N@28221|Deltaproteobacteria,2MIKM@213118|Desulfobacterales	28221|Deltaproteobacteria	N	ABC-type uncharacterized transport system	-	-	-	-	-	-	-	-	-	-	-	-	ABC_transp_aux
k59_101622_1	439235.Dalk_5067	9.09e-65	207.0	COG2048@1|root,COG2048@2|Bacteria,1RC7G@1224|Proteobacteria,43B85@68525|delta/epsilon subdivisions,2WMVG@28221|Deltaproteobacteria,2MJQR@213118|Desulfobacterales	28221|Deltaproteobacteria	C	heterodisulfide reductase, subunit	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03389	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	CCG
k59_101622_2	644282.Deba_0780	3.32e-09	57.0	COG1150@1|root,COG2181@1|root,COG1150@2|Bacteria,COG2181@2|Bacteria,1R44N@1224|Proteobacteria,42NTE@68525|delta/epsilon subdivisions,2WJN8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Nitrate reductase gamma subunit	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_17,Fer4_8,Nitrate_red_gam
k59_93767_1	1177928.TH2_15902	1.11e-28	107.0	2CEUC@1|root,32S0I@2|Bacteria,1MZ90@1224|Proteobacteria,2UCBC@28211|Alphaproteobacteria,2JTPS@204441|Rhodospirillales	204441|Rhodospirillales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_93767_2	335543.Sfum_3091	1.21e-66	206.0	COG2050@1|root,COG2050@2|Bacteria,1N66F@1224|Proteobacteria,42WVQ@68525|delta/epsilon subdivisions,2X2FE@28221|Deltaproteobacteria,2MSED@213462|Syntrophobacterales	28221|Deltaproteobacteria	Q	Domain of unknown function (DUF4442)	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
k59_93767_3	323848.Nmul_A2478	0.00029	43.9	COG1678@1|root,COG1678@2|Bacteria,1RCXM@1224|Proteobacteria,2VJQA@28216|Betaproteobacteria,372DD@32003|Nitrosomonadales	28216|Betaproteobacteria	K	Belongs to the UPF0301 (AlgH) family	algH	-	-	ko:K07735	-	-	-	-	ko00000,ko03000	-	-	-	DUF179
k59_25510_1	272562.CA_C0061	5.5e-19	95.5	COG1345@1|root,COG5412@1|root,COG1345@2|Bacteria,COG5412@2|Bacteria,1TPR1@1239|Firmicutes,24NN1@186801|Clostridia,36F0M@31979|Clostridiaceae	186801|Clostridia	D	tape measure	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_25511_1	1499967.BAYZ01000131_gene322	9.4e-69	218.0	COG3839@1|root,COG3839@2|Bacteria	2|Bacteria	P	tungstate ion transport	ugpC	-	3.6.3.55	ko:K06857,ko:K17325	ko02010,map02010	M00186,M00607	R10531	RC00002	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.1.35,3.A.1.6.2,3.A.1.6.4	-	-	ABC_tran,TOBE_2
k59_70938_1	555779.Dthio_PD1031	4.03e-78	249.0	COG0247@1|root,COG0247@2|Bacteria,1R467@1224|Proteobacteria,42Z6B@68525|delta/epsilon subdivisions,2WU13@28221|Deltaproteobacteria,2MH5B@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_17
k59_101629_1	706587.Desti_3270	7.91e-89	303.0	COG2202@1|root,COG2203@1|root,COG2204@1|root,COG4191@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG2204@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MC4@68525|delta/epsilon subdivisions,2WIU5@28221|Deltaproteobacteria,2MQZQ@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
k59_234348_1	1173026.Glo7428_3485	1.22e-56	191.0	COG0766@1|root,COG0766@2|Bacteria,1G1HX@1117|Cyanobacteria	1117|Cyanobacteria	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
k59_195395_1	639282.DEFDS_1582	1.12e-102	307.0	COG0687@1|root,COG0687@2|Bacteria,2GFTA@200930|Deferribacteres	200930|Deferribacteres	E	Bacterial extracellular solute-binding protein	-	-	-	ko:K11069	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	SBP_bac_8
k59_5414_2	443144.GM21_0081	7.64e-34	123.0	COG1047@1|root,COG1047@2|Bacteria,1RD35@1224|Proteobacteria,42MCS@68525|delta/epsilon subdivisions,2WV5U@28221|Deltaproteobacteria,43UX5@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	FKBP-type peptidyl-prolyl cis-trans isomerase	-	-	5.2.1.8	ko:K01802	-	-	-	-	ko00000,ko01000	-	-	-	FKBP_C
k59_97341_1	1122135.KB893134_gene3780	1.19e-52	177.0	COG3676@1|root,COG3677@1|root,COG3676@2|Bacteria,COG3677@2|Bacteria,1MXYX@1224|Proteobacteria,2TQR3@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS1595,Zn_Tnp_IS1595
k59_211496_1	1121918.ARWE01000001_gene1112	6.39e-25	106.0	COG0601@1|root,COG0601@2|Bacteria,1NS80@1224|Proteobacteria,42N5D@68525|delta/epsilon subdivisions,2WIRR@28221|Deltaproteobacteria,43S9X@69541|Desulfuromonadales	28221|Deltaproteobacteria	EP	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
k59_127884_1	443143.GM18_0136	9.79e-107	335.0	COG1032@1|root,COG5011@1|root,COG1032@2|Bacteria,COG5011@2|Bacteria,1MV5G@1224|Proteobacteria,42MPT@68525|delta/epsilon subdivisions,2WJG9@28221|Deltaproteobacteria,43UIU@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	DUF2344,Radical_SAM
k59_135776_1	1382359.JIAL01000001_gene2614	8.9e-27	108.0	COG1960@1|root,COG1960@2|Bacteria,3Y3T6@57723|Acidobacteria,2JIV6@204432|Acidobacteriia	204432|Acidobacteriia	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
k59_212027_1	1499967.BAYZ01000138_gene184	2.07e-133	386.0	28IMV@1|root,2Z8NA@2|Bacteria	2|Bacteria	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_150447_1	398767.Glov_0523	1.39e-38	139.0	COG2003@1|root,COG2003@2|Bacteria,1MXZ5@1224|Proteobacteria,42PPW@68525|delta/epsilon subdivisions,2WM1S@28221|Deltaproteobacteria,43SVY@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	metallopeptidase activity	radC	-	-	ko:K03630	-	-	-	-	ko00000	-	-	-	RadC
k59_212030_1	497965.Cyan7822_1448	2.66e-49	169.0	COG0392@1|root,COG0392@2|Bacteria,1G3F6@1117|Cyanobacteria,3KFWD@43988|Cyanothece	1117|Cyanobacteria	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	DUF2156,LPG_synthase_TM
k59_82955_1	1324957.K933_16842	3.57e-14	77.4	COG0380@1|root,arCOG02831@2157|Archaea,2XSTE@28890|Euryarchaeota,23TQX@183963|Halobacteria	183963|Halobacteria	G	COG0380 Trehalose-6-phosphate synthase	-	-	2.4.1.15,2.4.1.347	ko:K00697	ko00500,ko01100,map00500,map01100	-	R02737	RC00005,RC00049,RC02748	ko00000,ko00001,ko01000,ko01003	-	GT20	-	Glyco_transf_20
k59_90336_1	202954.BBNK01000012_gene1083	4.47e-05	49.3	COG0110@1|root,COG0110@2|Bacteria,1MZV9@1224|Proteobacteria,1RXAQ@1236|Gammaproteobacteria,3NMZH@468|Moraxellaceae	1236|Gammaproteobacteria	S	Hexapeptide repeat of succinyl-transferase	wxcM	-	-	-	-	-	-	-	-	-	-	-	FdtA,Hexapep
k59_52072_1	247490.KSU1_B0406	1.99e-84	262.0	arCOG06766@1|root,2Z87F@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_97781_1	177437.HRM2_38470	2.04e-84	266.0	COG0644@1|root,COG2440@1|root,COG0644@2|Bacteria,COG2440@2|Bacteria,1MVU6@1224|Proteobacteria,42PTE@68525|delta/epsilon subdivisions,2WKRZ@28221|Deltaproteobacteria,2MIH0@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Electron transfer flavoprotein-ubiquinone oxidoreductase	-	-	1.5.5.1	ko:K00311	-	-	-	-	ko00000,ko01000	-	-	-	ETF_QO
k59_105758_1	1499967.BAYZ01000111_gene2946	2.43e-81	268.0	COG0642@1|root,COG2205@2|Bacteria,2NS4W@2323|unclassified Bacteria	2|Bacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
k59_105758_2	1499967.BAYZ01000111_gene2947	3.82e-76	233.0	COG0745@1|root,COG0745@2|Bacteria,2NPCK@2323|unclassified Bacteria	2|Bacteria	T	Two component transcriptional regulator, winged helix family	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
k59_15070_1	933262.AXAM01000052_gene1999	1.56e-18	78.2	COG0186@1|root,COG0186@2|Bacteria,1MZIK@1224|Proteobacteria,42TNS@68525|delta/epsilon subdivisions,2WR6G@28221|Deltaproteobacteria,2MKWR@213118|Desulfobacterales	28221|Deltaproteobacteria	J	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA	rpsQ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02961	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S17
k59_15070_2	1226322.HMPREF1545_02727	4.41e-11	59.7	COG0255@1|root,COG0255@2|Bacteria,1UG3Q@1239|Firmicutes,25N9Y@186801|Clostridia,2N7Q5@216572|Oscillospiraceae	186801|Clostridia	J	Ribosomal L29 protein	rpmC	-	-	ko:K02904	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L29
k59_15070_3	177437.HRM2_36190	1.29e-12	63.9	COG0197@1|root,COG0197@2|Bacteria,1RA0Z@1224|Proteobacteria,42QW5@68525|delta/epsilon subdivisions,2WP71@28221|Deltaproteobacteria,2MJKH@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs	rplP	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904	-	ko:K02878	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L16
k59_136236_1	1144342.PMI40_01999	2.85e-10	66.6	COG1408@1|root,COG1408@2|Bacteria,1MUH5@1224|Proteobacteria,2VH7E@28216|Betaproteobacteria,473GY@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Calcineurin-like phosphoesterase	-	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	Metallophos
k59_52083_1	685778.AORL01000021_gene1229	9.06e-34	137.0	COG1749@1|root,COG1749@2|Bacteria,1MU5J@1224|Proteobacteria,2TSF2@28211|Alphaproteobacteria,2KD3N@204457|Sphingomonadales	204457|Sphingomonadales	N	Flagellar basal body rod protein	-	-	-	ko:K02390	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FlaE,Flg_bb_rod,Flg_bbr_C
k59_218946_1	335543.Sfum_2600	1.92e-64	210.0	COG3547@1|root,COG3547@2|Bacteria,1NGR7@1224|Proteobacteria,42NNQ@68525|delta/epsilon subdivisions,2WM2H@28221|Deltaproteobacteria,2MSJJ@213462|Syntrophobacterales	28221|Deltaproteobacteria	L	PFAM transposase IS116 IS110 IS902 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_37461_1	933262.AXAM01000042_gene1834	5.44e-77	241.0	COG0620@1|root,COG0620@2|Bacteria,1R6KI@1224|Proteobacteria,42PCN@68525|delta/epsilon subdivisions,2WKT3@28221|Deltaproteobacteria,2MID3@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_150471_1	1121405.dsmv_3406	9.29e-33	125.0	COG0707@1|root,COG0707@2|Bacteria,1MVIB@1224|Proteobacteria,42ME1@68525|delta/epsilon subdivisions,2WJNY@28221|Deltaproteobacteria,2MHZT@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
k59_204217_1	439235.Dalk_0122	1.08e-09	60.1	COG0589@1|root,COG0589@2|Bacteria,1N2H4@1224|Proteobacteria,42UE7@68525|delta/epsilon subdivisions,2WQV7@28221|Deltaproteobacteria,2MKEV@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
k59_15082_1	1121405.dsmv_0958	1.45e-70	227.0	COG1061@1|root,COG1061@2|Bacteria,1QWMJ@1224|Proteobacteria,42NXF@68525|delta/epsilon subdivisions,2WJWA@28221|Deltaproteobacteria,2MHPY@213118|Desulfobacterales	28221|Deltaproteobacteria	L	type III restriction protein res subunit	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,ResIII
k59_105773_1	1121346.KB899853_gene136	2.33e-17	87.0	COG4974@1|root,COG4974@2|Bacteria,1UA9R@1239|Firmicutes,4HUK0@91061|Bacilli	91061|Bacilli	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_5,Phage_integrase
k59_120485_1	1265505.ATUG01000001_gene4461	4.43e-67	216.0	COG0477@1|root,COG2814@2|Bacteria,1MVSH@1224|Proteobacteria,42NA4@68525|delta/epsilon subdivisions,2WKTU@28221|Deltaproteobacteria,2MHYA@213118|Desulfobacterales	28221|Deltaproteobacteria	EGP	PFAM Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_1_like,MFS_3,Sugar_tr
k59_143819_1	592015.HMPREF1705_01096	1.9e-38	137.0	COG0752@1|root,COG0752@2|Bacteria,3TA64@508458|Synergistetes	508458|Synergistetes	J	glycyl-tRNA synthetase alpha subunit	glyQ	-	6.1.1.14	ko:K01878	ko00970,map00970	M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2e
k59_143819_2	1121430.JMLG01000001_gene2240	3.13e-16	79.7	COG0751@1|root,COG0751@2|Bacteria,1TNZ7@1239|Firmicutes,248RS@186801|Clostridia,2608I@186807|Peptococcaceae	186801|Clostridia	J	Glycyl-tRNA synthetase beta subunit	glyS	-	6.1.1.14	ko:K01879	ko00970,map00970	M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_1,tRNA_synt_2f
k59_75101_1	335543.Sfum_1278	1.36e-91	289.0	COG0427@1|root,COG0454@1|root,COG0427@2|Bacteria,COG0456@2|Bacteria,1MUGE@1224|Proteobacteria,42MHC@68525|delta/epsilon subdivisions,2WINZ@28221|Deltaproteobacteria,2MR2F@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	acetyl-CoA	-	-	-	ko:K18122,ko:K18288	ko00650,ko00660,ko01100,ko01200,map00650,map00660,map01100,map01200	-	R02407,R05336,R10600	RC00012,RC00014	ko00000,ko00001,ko01000	-	-	iAF987.Gmet_2142,iAF987.Gmet_3304	AcetylCoA_hyd_C,AcetylCoA_hydro,Acetyltransf_1,Acetyltransf_3
k59_120488_1	573063.Metin_0273	7.29e-26	108.0	COG1962@1|root,arCOG04336@2157|Archaea,2XV9A@28890|Euryarchaeota,23QMN@183939|Methanococci	183939|Methanococci	H	Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step. MtrH catalyzes the transfer of the methyl group from methyl-tetrahydromethanopterin to the corrinoid prosthetic group of MtrA	mtrH	-	2.1.1.86	ko:K00584	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00357,M00567	R04347	RC00035,RC00113,RC02892	ko00000,ko00001,ko00002,ko01000	-	-	-	MtrH
k59_218964_1	1122604.JONR01000007_gene2812	4.98e-43	161.0	COG0841@1|root,COG0841@2|Bacteria,1QXYC@1224|Proteobacteria,1T3KA@1236|Gammaproteobacteria,1XDE0@135614|Xanthomonadales	135614|Xanthomonadales	V	MMPL family	-	-	-	-	-	-	-	-	-	-	-	-	MMPL
k59_52102_1	335543.Sfum_2126	1.63e-22	90.9	COG0537@1|root,COG0537@2|Bacteria,1RHYQ@1224|Proteobacteria,42SEG@68525|delta/epsilon subdivisions,2WPFW@28221|Deltaproteobacteria,2MRQA@213462|Syntrophobacterales	28221|Deltaproteobacteria	FG	Scavenger mRNA decapping enzyme C-term binding	-	-	2.7.7.53	ko:K19710	ko00230,map00230	-	R00126,R01618	RC00002,RC02753,RC02795	ko00000,ko00001,ko01000	-	-	-	CwfJ_C_1,HIT
k59_52102_2	641491.DND132_0464	9.71e-11	62.4	COG5416@1|root,COG5416@2|Bacteria,1NNQS@1224|Proteobacteria,42Y27@68525|delta/epsilon subdivisions,2WSRP@28221|Deltaproteobacteria,2MDFK@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Lipopolysaccharide assembly protein A domain	-	-	-	-	-	-	-	-	-	-	-	-	LapA_dom
k59_105781_2	324925.Ppha_0360	3.42e-22	95.5	COG0745@1|root,COG2202@1|root,COG3829@1|root,COG0745@2|Bacteria,COG2202@2|Bacteria,COG3829@2|Bacteria,1FF5G@1090|Chlorobi	1090|Chlorobi	KT	SMART PAS domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	PAS_9
k59_241596_1	1499967.BAYZ01000171_gene5615	2.69e-75	248.0	COG0392@1|root,COG2898@1|root,COG0392@2|Bacteria,COG2898@2|Bacteria	2|Bacteria	K	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms	mprF	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	2.3.2.3	ko:K07027,ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	M00726	-	-	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	2.A.1.3.37,4.D.2	-	iYO844.BG12900	DUF2156,LPG_synthase_TM
k59_60331_1	439235.Dalk_3962	1.95e-99	301.0	COG1350@1|root,COG1350@2|Bacteria,1N07Y@1224|Proteobacteria,42MPB@68525|delta/epsilon subdivisions,2WJUV@28221|Deltaproteobacteria,2MJ5P@213118|Desulfobacterales	28221|Deltaproteobacteria	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB2	-	4.2.1.20	ko:K06001	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
k59_218972_1	1307759.JOMJ01000004_gene2844	2.84e-36	140.0	COG1132@1|root,COG1132@2|Bacteria,1MWTY@1224|Proteobacteria,42N23@68525|delta/epsilon subdivisions,2WKW2@28221|Deltaproteobacteria,2M7Z1@213115|Desulfovibrionales	28221|Deltaproteobacteria	V	ABC transporter, transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	ABC_membrane,ABC_tran
k59_44390_1	1121396.KB893012_gene4082	6.25e-39	142.0	COG4177@1|root,COG4177@2|Bacteria,1MV66@1224|Proteobacteria,42MAQ@68525|delta/epsilon subdivisions,2WKK0@28221|Deltaproteobacteria,2MINE@213118|Desulfobacterales	28221|Deltaproteobacteria	E	transport system permease	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
k59_218981_1	1121405.dsmv_0056	3.92e-09	58.9	COG1141@1|root,COG3383@1|root,COG1141@2|Bacteria,COG3383@2|Bacteria,1RAIK@1224|Proteobacteria,42SGD@68525|delta/epsilon subdivisions,2WP4S@28221|Deltaproteobacteria,2MJN9@213118|Desulfobacterales	28221|Deltaproteobacteria	C	2Fe-2S iron-sulfur cluster binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer2_4,Fer4,Fer4_7
k59_218981_2	1232437.KL661961_gene3040	3.11e-34	118.0	2EDHV@1|root,337DV@2|Bacteria,1NEJZ@1224|Proteobacteria,42V5G@68525|delta/epsilon subdivisions,2WRIF@28221|Deltaproteobacteria,2MKYD@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_52116_1	47763.JNZA01000014_gene335	1.96e-51	177.0	COG1903@1|root,COG1903@2|Bacteria,2GM41@201174|Actinobacteria	201174|Actinobacteria	H	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A	cbiD	-	2.1.1.195	ko:K02188	ko00860,ko01100,map00860,map01100	-	R07773	RC00003,RC02051	ko00000,ko00001,ko01000	-	-	-	CbiD
k59_120523_1	469381.Dpep_1250	4.76e-50	179.0	COG4907@1|root,COG4907@2|Bacteria,3TA8F@508458|Synergistetes	508458|Synergistetes	S	membrane protein (DUF2207)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2207
k59_143828_1	313606.M23134_02755	7.71e-16	73.2	COG3436@1|root,COG3436@2|Bacteria,4NV0F@976|Bacteroidetes,47X5Z@768503|Cytophagia	976|Bacteroidetes	L	IS66 Orf2 like protein	-	-	-	ko:K07484	-	-	-	-	ko00000	-	-	-	TnpB_IS66
k59_21784_1	1121405.dsmv_3644	2.08e-66	224.0	COG0086@1|root,COG0086@2|Bacteria,1MU3M@1224|Proteobacteria,42NAW@68525|delta/epsilon subdivisions,2WISU@28221|Deltaproteobacteria,2MIYJ@213118|Desulfobacterales	28221|Deltaproteobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	-	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
k59_21784_2	933262.AXAM01000079_gene2202	2.02e-114	364.0	COG0085@1|root,COG0085@2|Bacteria,1MUC4@1224|Proteobacteria,43DMZ@68525|delta/epsilon subdivisions,2WIW5@28221|Deltaproteobacteria,2MI5C@213118|Desulfobacterales	28221|Deltaproteobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
k59_113313_1	96561.Dole_3007	9.52e-86	259.0	COG0410@1|root,COG0410@2|Bacteria,1MVVC@1224|Proteobacteria,42QDN@68525|delta/epsilon subdivisions,2WKRW@28221|Deltaproteobacteria,2MMXT@213118|Desulfobacterales	28221|Deltaproteobacteria	E	ABC transporter	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
k59_83018_1	439235.Dalk_0710	2.36e-133	387.0	COG0436@1|root,COG0436@2|Bacteria,1MWS8@1224|Proteobacteria,42MEF@68525|delta/epsilon subdivisions,2WJ4D@28221|Deltaproteobacteria,2MI6F@213118|Desulfobacterales	28221|Deltaproteobacteria	E	PFAM aminotransferase class I and II	yfdZ	-	2.6.1.83	ko:K10206,ko:K14261	ko00300,ko01100,ko01110,ko01130,ko01230,map00300,map01100,map01110,map01130,map01230	M00527	R07613	RC00006,RC01847	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
k59_90408_1	335543.Sfum_1550	1.97e-103	332.0	COG0086@1|root,COG0086@2|Bacteria,1MU3M@1224|Proteobacteria,42NAW@68525|delta/epsilon subdivisions,2WISU@28221|Deltaproteobacteria,2MR5Q@213462|Syntrophobacterales	28221|Deltaproteobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	-	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
k59_226631_1	1151127.KB906325_gene4525	0.000278	51.6	COG2203@1|root,COG3899@1|root,COG4191@1|root,COG2203@2|Bacteria,COG3899@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,1RR5W@1236|Gammaproteobacteria,1YQ0P@136843|Pseudomonas fluorescens group	1236|Gammaproteobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	AAA_16,GAF,HATPase_c,HisKA,MASE1,PAS_3,PAS_4,PAS_9,Pkinase
k59_165727_1	1235799.C818_03775	2.28e-63	214.0	COG0446@1|root,COG1902@1|root,COG0446@2|Bacteria,COG1902@2|Bacteria,1TPM6@1239|Firmicutes,247V1@186801|Clostridia,27I89@186928|unclassified Lachnospiraceae	186801|Clostridia	C	NADH:flavin oxidoreductase / NADH oxidase family	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_FMN,Pyr_redox_2
k59_158679_1	1499967.BAYZ01000014_gene6353	3.18e-55	189.0	COG0297@1|root,COG0297@2|Bacteria,2NP1F@2323|unclassified Bacteria	2|Bacteria	G	Synthesizes alpha-1,4-glucan chains using ADP-glucose	glgA	GO:0003674,GO:0003824,GO:0016740,GO:0016757	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Glyco_transf_5,Glycos_transf_1
k59_241608_1	1429916.X566_01530	2.11e-37	138.0	28M7D@1|root,2ZAKV@2|Bacteria,1R6BC@1224|Proteobacteria,2U3UN@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_120543_1	1121405.dsmv_3465	2.61e-69	220.0	COG0568@1|root,COG0568@2|Bacteria,1MVWR@1224|Proteobacteria,42NRM@68525|delta/epsilon subdivisions,2WJ0S@28221|Deltaproteobacteria,2MHVP@213118|Desulfobacterales	28221|Deltaproteobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	rpoH	-	-	ko:K03086,ko:K03089	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
k59_234853_2	1479238.JQMZ01000001_gene101	1.82e-29	108.0	COG3118@1|root,COG3118@2|Bacteria,1MZBB@1224|Proteobacteria,2UCCR@28211|Alphaproteobacteria,43Y3Z@69657|Hyphomonadaceae	28211|Alphaproteobacteria	O	Belongs to the thioredoxin family	trxA	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
k59_173782_1	1293054.HSACCH_02358	3.15e-15	75.5	COG3842@1|root,COG3842@2|Bacteria,1TP2M@1239|Firmicutes,247JR@186801|Clostridia,3WABU@53433|Halanaerobiales	186801|Clostridia	P	ABC transporter	-	-	3.6.3.55	ko:K15497	ko02010,map02010	M00423	R10531	RC00002	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.6.5	-	-	ABC_tran,TOBE_2
k59_173782_2	1499967.BAYZ01000117_gene3315	1.83e-130	378.0	COG1840@1|root,COG1840@2|Bacteria	2|Bacteria	P	iron ion homeostasis	-	-	-	ko:K02012	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	SBP_bac_6
k59_21811_1	1347392.CCEZ01000018_gene1143	1.12e-33	131.0	COG1120@1|root,COG1120@2|Bacteria,1TP2Q@1239|Firmicutes,2492Z@186801|Clostridia,36EEP@31979|Clostridiaceae	186801|Clostridia	HP	ABC transporter	-	-	3.6.3.34	ko:K02013	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	ABC_tran
k59_75144_1	311424.DhcVS_812	2.61e-79	243.0	COG0410@1|root,COG0410@2|Bacteria,2G654@200795|Chloroflexi,34D18@301297|Dehalococcoidia	301297|Dehalococcoidia	E	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
k59_83039_1	1121405.dsmv_2864	5.38e-90	273.0	COG1173@1|root,COG1173@2|Bacteria,1MUG0@1224|Proteobacteria,43B4R@68525|delta/epsilon subdivisions,2X5VN@28221|Deltaproteobacteria,2MITT@213118|Desulfobacterales	28221|Deltaproteobacteria	EP	N-terminal TM domain of oligopeptide transport permease C	-	-	-	ko:K02034,ko:K12370	ko02010,ko02024,map02010,map02024	M00239,M00324	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
k59_173796_1	335543.Sfum_3570	1.12e-138	404.0	COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,42MQI@68525|delta/epsilon subdivisions,2WN1S@28221|Deltaproteobacteria,2MR7B@213462|Syntrophobacterales	28221|Deltaproteobacteria	E	Aminotransferase class I and II	-	-	2.6.1.2	ko:K00814	ko00220,ko00250,ko00710,ko01100,ko01120,ko01200,ko01210,ko01230,map00220,map00250,map00710,map01100,map01120,map01200,map01210,map01230	M00171	R00258	RC00006,RC00008	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
k59_234867_2	96561.Dole_2665	1.59e-49	164.0	COG0727@1|root,COG0727@2|Bacteria,1R3YG@1224|Proteobacteria,42NM0@68525|delta/epsilon subdivisions,2WM96@28221|Deltaproteobacteria,2MHSQ@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Putative zinc- or iron-chelating domain	-	-	-	ko:K06940	-	-	-	-	ko00000	-	-	-	CxxCxxCC
k59_219018_1	1121405.dsmv_1603	1.69e-55	174.0	COG3118@1|root,COG3118@2|Bacteria,1MZBB@1224|Proteobacteria,42TPU@68525|delta/epsilon subdivisions,2WQ1M@28221|Deltaproteobacteria,2MKJV@213118|Desulfobacterales	28221|Deltaproteobacteria	O	Belongs to the thioredoxin family	trxA	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
k59_113359_1	439235.Dalk_4430	2.41e-41	147.0	COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,42M9N@68525|delta/epsilon subdivisions,2WIZR@28221|Deltaproteobacteria,2MHKG@213118|Desulfobacterales	28221|Deltaproteobacteria	G	PFAM TRAP C4-dicarboxylate transport system permease DctM subunit	-	-	-	-	-	-	-	-	-	-	-	-	DctM
k59_113359_2	1499967.BAYZ01000093_gene4022	5.41e-17	77.8	COG3090@1|root,COG3090@2|Bacteria	2|Bacteria	G	Trap-type c4-dicarboxylate transport system, small permease component	-	-	-	ko:K11689	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.56.1	-	-	DctQ
k59_143861_1	1430440.MGMSRv2_1913	2.01e-05	52.0	2DBCS@1|root,2Z8FF@2|Bacteria,1QVT2@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_94759_2	335543.Sfum_1754	3.83e-44	152.0	COG1277@1|root,COG1277@2|Bacteria,1NZZ9@1224|Proteobacteria,42SH9@68525|delta/epsilon subdivisions,2WPWW@28221|Deltaproteobacteria,2MRMI@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC2_membrane_3,ABC_transp_aux
k59_192997_1	596151.DesfrDRAFT_1895	3.97e-98	305.0	COG1148@1|root,COG1148@2|Bacteria,1QUM4@1224|Proteobacteria,42MPP@68525|delta/epsilon subdivisions,2WJ3U@28221|Deltaproteobacteria,2MEP8@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	4Fe-4S ferredoxin iron-sulfur binding	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_7,Pyr_redox_2
k59_79738_1	179408.Osc7112_2341	5.89e-168	483.0	COG3335@1|root,COG3335@2|Bacteria,1GQVS@1117|Cyanobacteria,1HC3Z@1150|Oscillatoriales	1117|Cyanobacteria	L	Rhodopirellula transposase family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISAZ013
k59_125333_1	266117.Rxyl_3051	4.5e-80	256.0	COG3385@1|root,COG3385@2|Bacteria	2|Bacteria	L	transposase activity	-	-	-	-	-	-	-	-	-	-	-	-	DDE_5,DDE_Tnp_1
k59_79742_1	1167006.UWK_01424	1.53e-56	190.0	COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,42MK4@68525|delta/epsilon subdivisions,2WJJ8@28221|Deltaproteobacteria,2MI9P@213118|Desulfobacterales	28221|Deltaproteobacteria	G	PFAM TRAP C4-dicarboxylate transport system permease DctM subunit	-	-	-	-	-	-	-	-	-	-	-	-	DctM,DctQ
k59_231449_1	1382304.JNIL01000001_gene275	6.03e-50	174.0	COG3039@1|root,COG3039@2|Bacteria,1TRUS@1239|Firmicutes,4HCCQ@91061|Bacilli	91061|Bacilli	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_2,DUF772
k59_72041_2	237368.SCABRO_01247	1.04e-44	152.0	COG3335@1|root,COG3335@2|Bacteria,2J1BU@203682|Planctomycetes	203682|Planctomycetes	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3
k59_132824_1	1121012.AUKX01000071_gene3243	1.1e-37	139.0	COG3666@1|root,COG3666@2|Bacteria,4NEDD@976|Bacteroidetes,1HYXT@117743|Flavobacteriia,23HQW@178469|Arenibacter	976|Bacteroidetes	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_6,DUF772
k59_102497_1	96561.Dole_1776	6.06e-76	246.0	COG4191@1|root,COG4191@2|Bacteria,1R9AK@1224|Proteobacteria,42Q2G@68525|delta/epsilon subdivisions,2WM8Y@28221|Deltaproteobacteria,2MI84@213118|Desulfobacterales	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
k59_238582_1	706587.Desti_2954	1.49e-76	246.0	COG1960@1|root,COG1960@2|Bacteria,1MU20@1224|Proteobacteria,42MUH@68525|delta/epsilon subdivisions,2WJ16@28221|Deltaproteobacteria,2MR2Y@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	PFAM Acyl-CoA dehydrogenase	-	-	-	ko:K09456	-	-	-	-	ko00000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_C,Acyl-CoA_dh_M,Acyl-CoA_dh_N,AcylCoA_DH_N
k59_64305_1	1232428.CAVO010000006_gene1063	3.54e-05	46.6	COG0668@1|root,COG0668@2|Bacteria,1TR9Z@1239|Firmicutes,4H5JY@909932|Negativicutes	909932|Negativicutes	M	Transporter, small conductance mechanosensitive ion channel MscS family protein	-	-	-	ko:K03442	-	-	-	-	ko00000,ko02000	1.A.23.2	-	-	MS_channel,TM_helix
k59_117067_1	933262.AXAM01000017_gene3127	2.94e-27	106.0	COG0546@1|root,COG0546@2|Bacteria,1MY9Y@1224|Proteobacteria,42SSC@68525|delta/epsilon subdivisions,2WN7Q@28221|Deltaproteobacteria,2MKDC@213118|Desulfobacterales	28221|Deltaproteobacteria	S	haloacid dehalogenase superfamily, subfamily IA, variant 1 with third motif having Dx(3-4)D or Dx(3-4)E	-	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
k59_231452_1	402880.MmarC5_0439	7.72e-29	118.0	COG0034@1|root,arCOG00093@2157|Archaea,2XSWJ@28890|Euryarchaeota,23Q7H@183939|Methanococci	183939|Methanococci	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_7,Pribosyltran
k59_86953_1	1121406.JAEX01000018_gene2820	7.54e-07	52.0	COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,1MVI9@1224|Proteobacteria,42NB4@68525|delta/epsilon subdivisions,2WK9E@28221|Deltaproteobacteria,2M8NV@213115|Desulfovibrionales	28221|Deltaproteobacteria	DM	PFAM lipopolysaccharide biosynthesis protein	wzc2	-	-	ko:K16554	ko05111,map05111	-	-	-	ko00000,ko00001,ko02000	8.A.3.1	-	-	AAA_31,CbiA,GNVR,ParA,Wzz
k59_208754_1	1121930.AQXG01000003_gene2564	5.36e-40	146.0	COG1972@1|root,COG1972@2|Bacteria,4NEYN@976|Bacteroidetes,1IRNQ@117747|Sphingobacteriia	976|Bacteroidetes	F	Na dependent nucleoside transporter	nupC	-	-	ko:K03317	-	-	-	-	ko00000	2.A.41	-	-	Gate,Nucleos_tra2_C,Nucleos_tra2_N
k59_11631_1	483219.LILAB_02170	4.69e-17	88.2	COG0457@1|root,COG0457@2|Bacteria,1PC4W@1224|Proteobacteria,438IM@68525|delta/epsilon subdivisions,2X3TG@28221|Deltaproteobacteria,2YX2F@29|Myxococcales	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_208758_1	268407.PWYN_19590	7.92e-76	236.0	COG0604@1|root,COG0604@2|Bacteria,1TSWF@1239|Firmicutes,4HANV@91061|Bacilli,274FR@186822|Paenibacillaceae	91061|Bacilli	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N,ADH_zinc_N_2
k59_186156_1	96561.Dole_0669	3.38e-82	258.0	COG0124@1|root,COG0124@2|Bacteria,1MV2K@1224|Proteobacteria,42MG0@68525|delta/epsilon subdivisions,2WJE1@28221|Deltaproteobacteria,2MI2D@213118|Desulfobacterales	28221|Deltaproteobacteria	J	TIGRFAM histidyl-tRNA synthetase	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
k59_193006_1	158189.SpiBuddy_2443	9.11e-100	299.0	COG1172@1|root,COG1172@2|Bacteria,2J781@203691|Spirochaetes	203691|Spirochaetes	G	PFAM Branched-chain amino acid transport system permease component	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
k59_64310_1	883.DvMF_1881	3.4e-27	114.0	COG0840@1|root,COG5278@1|root,COG0840@2|Bacteria,COG5278@2|Bacteria,1MU9B@1224|Proteobacteria,42Q64@68525|delta/epsilon subdivisions,2WKDM@28221|Deltaproteobacteria,2M9JV@213115|Desulfovibrionales	28221|Deltaproteobacteria	NT	Four helix bundle sensory module for signal transduction	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,CZB,HAMP,MCPsignal
k59_64310_2	1265505.ATUG01000003_gene800	0.000383	41.6	COG0834@1|root,COG0834@2|Bacteria,1RHMR@1224|Proteobacteria,42TGV@68525|delta/epsilon subdivisions,2WQZJ@28221|Deltaproteobacteria,2MKSF@213118|Desulfobacterales	28221|Deltaproteobacteria	ET	ABC-type amino acid transport signal transduction systems periplasmic component domain	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_79750_1	335543.Sfum_1220	1.59e-185	538.0	COG3276@1|root,COG3276@2|Bacteria,1MWXH@1224|Proteobacteria,42M49@68525|delta/epsilon subdivisions,2WJ5G@28221|Deltaproteobacteria,2MR17@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	Elongation factor Tu domain 2	selB	-	-	ko:K03833	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,SelB-wing_2,SelB-wing_3
k59_18681_1	1265505.ATUG01000002_gene2077	1.31e-96	301.0	COG4231@1|root,COG4231@2|Bacteria,1MUKS@1224|Proteobacteria,42N44@68525|delta/epsilon subdivisions,2WIX6@28221|Deltaproteobacteria,2MHSF@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates	iorA	-	1.2.7.8	ko:K00179	-	-	-	-	br01601,ko00000,ko01000	-	-	-	Fer4,POR_N,TPP_enzyme_C
k59_57084_1	439235.Dalk_0422	1.92e-60	198.0	COG0429@1|root,COG0429@2|Bacteria,1MWV1@1224|Proteobacteria,42S0M@68525|delta/epsilon subdivisions,2WNYE@28221|Deltaproteobacteria,2MMEA@213118|Desulfobacterales	28221|Deltaproteobacteria	S	alpha/beta hydrolase fold	yheT	-	-	ko:K07019	-	-	-	-	ko00000	-	-	-	Abhydrolase_1,Abhydrolase_6
k59_26205_1	5039.XP_002622232.1	0.000677	43.5	KOG1406@1|root,KOG1406@2759|Eukaryota,38CKQ@33154|Opisthokonta,3NVYV@4751|Fungi,3QPDS@4890|Ascomycota,20FDQ@147545|Eurotiomycetes,3B15A@33183|Onygenales	4751|Fungi	I	sterol carrier protein	-	-	2.3.1.176	ko:K08764	ko00120,ko01100,ko03320,ko04146,map00120,map01100,map03320,map04146	M00104	R03719,R04811	RC00004,RC00405,RC02725	ko00000,ko00001,ko00002,ko01000	-	-	-	Thiolase_C,Thiolase_N
k59_26205_2	562970.Btus_1990	5.91e-24	101.0	COG0183@1|root,COG0183@2|Bacteria,1TT8U@1239|Firmicutes,4HDWF@91061|Bacilli,279X4@186823|Alicyclobacillaceae	91061|Bacilli	I	Thiolase, C-terminal domain	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
k59_11645_1	335543.Sfum_0826	3.85e-73	240.0	COG4191@1|root,COG4191@2|Bacteria,1R682@1224|Proteobacteria,42P91@68525|delta/epsilon subdivisions,2WKQI@28221|Deltaproteobacteria,2MR7I@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	Signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4,PAS_9
k59_94788_1	859653.HIMB5_00013750	2.95e-10	63.2	COG0169@1|root,COG0169@2|Bacteria,1MVH4@1224|Proteobacteria,2TS99@28211|Alphaproteobacteria,4BQ53@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	E	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	aroE	-	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	-	Shikimate_DH,Shikimate_dh_N
k59_94788_2	439235.Dalk_3262	3.73e-62	193.0	COG0745@1|root,COG0745@2|Bacteria,1RINR@1224|Proteobacteria,42T1R@68525|delta/epsilon subdivisions,2WPHY@28221|Deltaproteobacteria,2MK8T@213118|Desulfobacterales	28221|Deltaproteobacteria	T	PFAM response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
k59_94788_3	879212.DespoDRAFT_03247	1.79e-08	54.7	COG0685@1|root,COG0685@2|Bacteria,1MXTZ@1224|Proteobacteria,42NTS@68525|delta/epsilon subdivisions,2WK04@28221|Deltaproteobacteria,2MIIA@213118|Desulfobacterales	28221|Deltaproteobacteria	E	PFAM Methylenetetrahydrofolate reductase	-	-	1.5.1.20,2.1.1.10	ko:K00297,ko:K00547	ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523	M00377	R00650,R01224,R07168	RC00003,RC00035,RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	CdhD,MTHFR
k59_140437_1	177437.HRM2_15110	4.25e-91	279.0	COG3278@1|root,COG3278@2|Bacteria,1MU18@1224|Proteobacteria,42M5M@68525|delta/epsilon subdivisions,2WM27@28221|Deltaproteobacteria,2MJRK@213118|Desulfobacterales	28221|Deltaproteobacteria	C	cytochrome c oxidase	ccoN	-	1.9.3.1	ko:K00404	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	COX1
k59_34240_1	1041138.KB890233_gene2170	4.79e-61	209.0	COG0457@1|root,COG0607@1|root,COG2114@1|root,COG5616@1|root,COG0457@2|Bacteria,COG0607@2|Bacteria,COG2114@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,2TRUI@28211|Alphaproteobacteria,4B9BA@82115|Rhizobiaceae	28211|Alphaproteobacteria	T	Adenylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,HEAT_2,Rhodanese,TPR_16,TPR_19,TPR_8,TolB_N
k59_208769_1	1304885.AUEY01000001_gene3251	1.09e-83	276.0	COG0086@1|root,COG0086@2|Bacteria,1MU3M@1224|Proteobacteria,42NAW@68525|delta/epsilon subdivisions,2WISU@28221|Deltaproteobacteria,2MIYJ@213118|Desulfobacterales	28221|Deltaproteobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	-	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
k59_86971_1	1232437.KL662020_gene690	2.31e-40	154.0	COG0204@1|root,COG1647@1|root,COG0204@2|Bacteria,COG1647@2|Bacteria,1MVZP@1224|Proteobacteria,42NBK@68525|delta/epsilon subdivisions,2WIUP@28221|Deltaproteobacteria,2MHMP@213118|Desulfobacterales	28221|Deltaproteobacteria	I	Phosphate acyltransferases	-	-	3.1.1.1	ko:K03928	-	-	-	-	ko00000,ko01000	-	-	-	Acyltransferase,Hydrolase_4
k59_109926_1	883126.HMPREF9710_03468	2.75e-30	120.0	COG2358@1|root,COG2358@2|Bacteria,1PNJV@1224|Proteobacteria,2VI8H@28216|Betaproteobacteria,473TS@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	transport system, periplasmic component	-	-	-	-	-	-	-	-	-	-	-	-	NMT1_3
k59_186170_1	1469613.JT55_11180	1.18e-11	70.1	COG5002@1|root,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,2VDU7@28211|Alphaproteobacteria,3FDU1@34008|Rhodovulum	28211|Alphaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
k59_223530_1	933262.AXAM01000032_gene699	4.26e-80	256.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,42NB6@68525|delta/epsilon subdivisions,2WNAS@28221|Deltaproteobacteria,2MMUH@213118|Desulfobacterales	28221|Deltaproteobacteria	O	Trypsin	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
k59_193014_1	316058.RPB_4438	7.79e-15	70.5	COG4456@1|root,COG4456@2|Bacteria,1N06P@1224|Proteobacteria,2UEZJ@28211|Alphaproteobacteria,3K1I6@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	L	SpoVT / AbrB like domain	-	-	-	ko:K18829	-	-	-	-	ko00000,ko02048	-	-	-	MazE_antitoxin
k59_11657_1	443144.GM21_2067	4.43e-60	191.0	COG0717@1|root,COG0717@2|Bacteria	2|Bacteria	F	dUTP biosynthetic process	-	-	3.5.4.13	ko:K01494	ko00240,ko01100,map00240,map01100	M00053	R00568,R02325	RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	dUTPase
k59_200973_1	96561.Dole_0549	4.42e-28	103.0	COG0234@1|root,COG0234@2|Bacteria,1MZ2X@1224|Proteobacteria,42U7E@68525|delta/epsilon subdivisions,2WPZP@28221|Deltaproteobacteria,2MKH2@213118|Desulfobacterales	28221|Deltaproteobacteria	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
k59_64319_1	1408303.JNJJ01000009_gene2231	1.42e-41	153.0	COG0446@1|root,COG0446@2|Bacteria,1TPWW@1239|Firmicutes,4HA11@91061|Bacilli,1ZATE@1386|Bacillus	91061|Bacilli	P	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain	cdr2	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Pyr_redox_dim,Rhodanese
k59_208777_1	1231057.AMGD01000056_gene162	1.04e-27	114.0	COG0303@1|root,COG0303@2|Bacteria,1TQJ8@1239|Firmicutes,4HAFT@91061|Bacilli,26DNT@186818|Planococcaceae	91061|Bacilli	H	MoeA N-terminal region (domain I and II)	moeA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009144,GO:0009150,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0018130,GO:0019538,GO:0019637,GO:0019693,GO:0032324,GO:0034641,GO:0042278,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044464,GO:0046039,GO:0046128,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
k59_79764_1	522772.Dacet_1039	1.49e-27	119.0	COG3604@1|root,COG3604@2|Bacteria,2GEZF@200930|Deferribacteres	200930|Deferribacteres	KT	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	-	ko:K02584	ko02020,map02020	-	-	-	ko00000,ko00001,ko03000	-	-	-	GAF,GAF_2,HTH_8,Sigma54_activat
k59_170633_1	1123054.KB907705_gene2512	7.18e-06	50.1	COG1580@1|root,COG1580@2|Bacteria,1N0RT@1224|Proteobacteria,1S9SJ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	N	Controls the rotational direction of flagella during chemotaxis	fliL2	-	-	ko:K02415	-	-	-	-	ko00000,ko02035	-	-	-	FliL
k59_170633_2	1304885.AUEY01000005_gene784	2.57e-11	64.3	COG1868@1|root,COG1868@2|Bacteria,1MX01@1224|Proteobacteria,42N2Y@68525|delta/epsilon subdivisions,2WIS2@28221|Deltaproteobacteria,2MI59@213118|Desulfobacterales	28221|Deltaproteobacteria	N	flagellar motor switch protein FliM	fliM	-	-	ko:K02416	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliM,FliMN_C
k59_162822_1	981085.XP_010104274.1	8.75e-34	134.0	COG0751@1|root,2QS5T@2759|Eukaryota,37JRG@33090|Viridiplantae,3GB3M@35493|Streptophyta,4JEYV@91835|fabids	35493|Streptophyta	J	glycine--tRNA ligase	-	GO:0000003,GO:0003006,GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006426,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0007275,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009790,GO:0009791,GO:0009793,GO:0009987,GO:0010154,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0022414,GO:0032501,GO:0032502,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0045995,GO:0046483,GO:0046983,GO:0048316,GO:0048608,GO:0048731,GO:0048856,GO:0050789,GO:0050793,GO:0051239,GO:0061458,GO:0065007,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:2000026	6.1.1.14	ko:K14164	ko00970,map00970	M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	tRNA-synt_2e,tRNA_synt_2f
k59_34260_1	644282.Deba_2836	1.1e-28	116.0	COG1033@1|root,COG1033@2|Bacteria,1MUE1@1224|Proteobacteria,42ME2@68525|delta/epsilon subdivisions,2WJRI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	PFAM MMPL family	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
k59_34260_2	439235.Dalk_0752	3.24e-07	52.4	COG2834@1|root,COG2834@2|Bacteria,1MXW0@1224|Proteobacteria,42QPE@68525|delta/epsilon subdivisions,2WN39@28221|Deltaproteobacteria,2MJHS@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Protein of unknown function (DUF1329)	-	-	-	-	-	-	-	-	-	-	-	-	LolA_like
k59_49569_2	96561.Dole_0077	3.13e-14	72.4	COG4799@1|root,COG4799@2|Bacteria,1MVAX@1224|Proteobacteria,43AEE@68525|delta/epsilon subdivisions,2WIRF@28221|Deltaproteobacteria,2MIPI@213118|Desulfobacterales	28221|Deltaproteobacteria	I	PFAM carboxyl transferase	-	-	2.1.3.1,2.1.3.15,6.4.1.3	ko:K01966,ko:K17489	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	M00373,M00741	R00353,R01859	RC00040,RC00097,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
k59_232082_1	335543.Sfum_1797	2.33e-82	254.0	COG1143@1|root,COG1143@2|Bacteria,1R412@1224|Proteobacteria,42ND5@68525|delta/epsilon subdivisions,2WIR2@28221|Deltaproteobacteria,2MQSB@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_209287_1	338966.Ppro_0975	2.98e-32	118.0	COG1544@1|root,COG1544@2|Bacteria,1MZHW@1224|Proteobacteria,42SJW@68525|delta/epsilon subdivisions,2WPF7@28221|Deltaproteobacteria,43TY8@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase	hpf	-	-	ko:K05808	-	-	-	-	ko00000,ko03009	-	-	-	Ribosom_S30AE_C,Ribosomal_S30AE
k59_209287_2	335543.Sfum_2067	3.41e-55	176.0	COG1762@1|root,COG1762@2|Bacteria,1RD0E@1224|Proteobacteria,42SD2@68525|delta/epsilon subdivisions,2WP7H@28221|Deltaproteobacteria,2MQJW@213462|Syntrophobacterales	28221|Deltaproteobacteria	G	PFAM phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2	ptsN	-	-	ko:K02806	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	-	-	-	PTS_EIIA_2
k59_26589_1	1265505.ATUG01000003_gene496	1.11e-21	99.0	COG2905@1|root,COG2905@2|Bacteria,1MW8U@1224|Proteobacteria,42NAX@68525|delta/epsilon subdivisions,2WJF5@28221|Deltaproteobacteria,2MIA9@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Putative nucleotidyltransferase substrate binding domain	-	-	-	ko:K07182	-	-	-	-	ko00000	-	-	-	CBS,DUF294,DUF294_C,PAS_8,cNMP_binding,sCache_2
k59_57625_1	883096.HMPREF9699_01837	8.81e-41	152.0	COG1253@1|root,COG1253@2|Bacteria,4NDZ7@976|Bacteroidetes,1HXF3@117743|Flavobacteriia	976|Bacteroidetes	S	gliding motility-associated protein GldE	gldE	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,DUF21
k59_156135_2	1121403.AUCV01000056_gene3013	4.92e-40	137.0	COG3678@1|root,COG3678@2|Bacteria,1NW18@1224|Proteobacteria,43048@68525|delta/epsilon subdivisions,2WV68@28221|Deltaproteobacteria,2MNGN@213118|Desulfobacterales	28221|Deltaproteobacteria	NPTU	ATP-independent chaperone mediated protein folding	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_147775_1	1304872.JAGC01000003_gene3474	6.35e-105	335.0	COG1132@1|root,COG1132@2|Bacteria,1MWTY@1224|Proteobacteria,42N23@68525|delta/epsilon subdivisions,2WKW2@28221|Deltaproteobacteria,2M7Z1@213115|Desulfovibrionales	28221|Deltaproteobacteria	V	ABC transporter, transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	ABC_membrane,ABC_tran
k59_223855_1	596154.Alide2_2212	4.15e-25	110.0	COG1053@1|root,COG1053@2|Bacteria,1MU5M@1224|Proteobacteria,2VHM6@28216|Betaproteobacteria,4ABBD@80864|Comamonadaceae	28216|Betaproteobacteria	C	Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily	sdhA	GO:0000104,GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016627,GO:0016999,GO:0017144,GO:0019752,GO:0022900,GO:0032991,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045273,GO:0045274,GO:0045281,GO:0045282,GO:0045333,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072350,GO:0097159,GO:0098796,GO:0098797,GO:0098803,GO:1901265,GO:1901363,GO:1902494,GO:1990204	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
k59_110589_1	439235.Dalk_1445	6.86e-60	208.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2WJN5@28221|Deltaproteobacteria,2MHZ6@213118|Desulfobacterales	28221|Deltaproteobacteria	V	AcrB/AcrD/AcrF family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_186694_1	1265505.ATUG01000001_gene4044	2.44e-06	47.8	291H0@1|root,2ZP3M@2|Bacteria,1P8IE@1224|Proteobacteria,432V6@68525|delta/epsilon subdivisions,2WXWA@28221|Deltaproteobacteria,2MP3S@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_19184_1	224325.AF_1027	7.39e-42	153.0	COG2368@1|root,arCOG02143@2157|Archaea,2Y372@28890|Euryarchaeota,246UM@183980|Archaeoglobi	183980|Archaeoglobi	Q	4-hydroxyphenylacetate 3-hydroxylase C terminal	-	-	1.14.14.9,4.2.1.120,5.3.3.3	ko:K00483,ko:K14534	ko00350,ko00650,ko00720,ko01100,ko01120,ko01200,ko01220,map00350,map00650,map00720,map01100,map01120,map01200,map01220	M00374,M00375	R02698,R03031,R03299,R10782	RC00046,RC01857,RC03277	ko00000,ko00001,ko00002,ko01000	-	-	-	HpaB,HpaB_N
k59_201508_1	1121405.dsmv_3327	1.51e-29	108.0	COG2329@1|root,COG2329@2|Bacteria,1NBCH@1224|Proteobacteria,42VX2@68525|delta/epsilon subdivisions,2WRPB@28221|Deltaproteobacteria,2MM0B@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	ABM
k59_201508_2	1121405.dsmv_0417	0.000194	48.1	2EMAC@1|root,33EZD@2|Bacteria,1NMXS@1224|Proteobacteria,42WZR@68525|delta/epsilon subdivisions,2WTCM@28221|Deltaproteobacteria,2MM8Y@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4124
k59_87507_1	1304885.AUEY01000046_gene20	3.26e-77	246.0	COG1236@1|root,COG1236@2|Bacteria,1MUDD@1224|Proteobacteria,42N91@68525|delta/epsilon subdivisions,2WIMM@28221|Deltaproteobacteria,2MIKE@213118|Desulfobacterales	28221|Deltaproteobacteria	J	RNA-metabolising metallo-beta-lactamase	-	-	-	ko:K07576	-	-	-	-	ko00000	-	-	-	Beta-Casp,Lactamase_B,Lactamase_B_6,RMMBL
k59_216384_1	1231185.BAMP01000011_gene2068	7.65e-08	55.1	COG1734@1|root,COG1734@2|Bacteria,1RD08@1224|Proteobacteria,2U74V@28211|Alphaproteobacteria,43JKC@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	T	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters	dksA	-	-	ko:K06204	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000,ko03009,ko03021	-	-	-	zf-dskA_traR
k59_163150_1	1307759.JOMJ01000003_gene1714	3.29e-85	278.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2WJ8D@28221|Deltaproteobacteria,2M7S1@213115|Desulfovibrionales	28221|Deltaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
k59_156150_1	1190606.AJYG01000074_gene169	3.43e-64	213.0	COG1840@1|root,COG1840@2|Bacteria,1MXZ8@1224|Proteobacteria,1RPPC@1236|Gammaproteobacteria,1XSDQ@135623|Vibrionales	135623|Vibrionales	P	ABC-type Fe3 transport system, periplasmic component	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_6
k59_49601_1	1121456.ATVA01000001_gene3074	2.49e-47	154.0	COG2204@1|root,COG2204@2|Bacteria,1N33V@1224|Proteobacteria,42U3U@68525|delta/epsilon subdivisions,2WQ8H@28221|Deltaproteobacteria,2MBNT@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
k59_49601_2	641491.DND132_1373	1.4e-10	62.8	COG0574@1|root,COG3848@1|root,COG0574@2|Bacteria,COG3848@2|Bacteria,1QFX3@1224|Proteobacteria,42PIP@68525|delta/epsilon subdivisions,2WKWI@28221|Deltaproteobacteria,2MG9J@213115|Desulfovibrionales	28221|Deltaproteobacteria	G	PFAM Pyruvate phosphate dikinase, PEP pyruvate-binding	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PPDK_N
k59_209325_1	439235.Dalk_1317	9.35e-230	643.0	COG3039@1|root,COG3039@2|Bacteria,1MVTU@1224|Proteobacteria,42Q03@68525|delta/epsilon subdivisions,2WMFQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	Transposase domain (DUF772)	-	-	-	ko:K07481	-	-	-	-	ko00000	-	-	-	DDE_Tnp_1,DDE_Tnp_1_6,DUF772
k59_57639_1	56780.SYN_01535	5.84e-27	111.0	COG1381@1|root,COG1381@2|Bacteria,1RIBW@1224|Proteobacteria,42PUE@68525|delta/epsilon subdivisions,2WK4W@28221|Deltaproteobacteria,2MQM5@213462|Syntrophobacterales	28221|Deltaproteobacteria	L	Involved in DNA repair and RecF pathway recombination	recO	-	-	ko:K03584	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecO_C,RecO_N
k59_216404_1	641491.DND132_1373	3.61e-26	112.0	COG0574@1|root,COG3848@1|root,COG0574@2|Bacteria,COG3848@2|Bacteria,1QFX3@1224|Proteobacteria,42PIP@68525|delta/epsilon subdivisions,2WKWI@28221|Deltaproteobacteria,2MG9J@213115|Desulfovibrionales	28221|Deltaproteobacteria	G	PFAM Pyruvate phosphate dikinase, PEP pyruvate-binding	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PPDK_N
k59_144385_2	96561.Dole_2807	1.07e-96	296.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,2MIB8@213118|Desulfobacterales	28221|Deltaproteobacteria	T	response regulator receiver	-	-	-	ko:K02481,ko:K07713	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
k59_61105_2	880072.Desac_0829	5.9e-82	258.0	COG0527@1|root,COG0527@2|Bacteria,1NAE6@1224|Proteobacteria,42VF1@68525|delta/epsilon subdivisions,2WSF3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	aspartate kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_227767_1	879212.DespoDRAFT_00838	3.77e-56	193.0	COG0497@1|root,COG0497@2|Bacteria,1MUNP@1224|Proteobacteria,42N50@68525|delta/epsilon subdivisions,2WJ23@28221|Deltaproteobacteria,2MHTD@213118|Desulfobacterales	28221|Deltaproteobacteria	L	May be involved in recombinational repair of damaged DNA	recN	-	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,SMC_N
k59_53432_1	1219049.SP5_067_00180	3.83e-14	72.0	COG0438@1|root,COG0438@2|Bacteria,1MWSZ@1224|Proteobacteria,2U3HT@28211|Alphaproteobacteria,2KCTF@204457|Sphingomonadales	204457|Sphingomonadales	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
k59_53432_2	1121396.KB893077_gene740	3.73e-41	144.0	COG2152@1|root,COG2152@2|Bacteria,1MX8M@1224|Proteobacteria,42QDF@68525|delta/epsilon subdivisions,2WMG5@28221|Deltaproteobacteria,2MJJI@213118|Desulfobacterales	28221|Deltaproteobacteria	G	beta-1,4-mannooligosaccharide phosphorylase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_130
k59_205104_1	96561.Dole_1849	4.61e-87	274.0	COG0166@1|root,COG0166@2|Bacteria,1MUFP@1224|Proteobacteria,42MNB@68525|delta/epsilon subdivisions,2WJ0I@28221|Deltaproteobacteria,2MIAG@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Belongs to the GPI family	pgi	-	5.3.1.9	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI
k59_76177_1	997830.HMPREF1124_1526	9.5e-53	187.0	COG1198@1|root,COG1198@2|Bacteria,1TNYB@1239|Firmicutes,4H9WW@91061|Bacilli,43FRD@68892|Streptococcus infantis	91061|Bacilli	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,ResIII
k59_61115_1	86106.I862_02625	5e-26	108.0	COG0745@1|root,COG2199@1|root,COG0745@2|Bacteria,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,2TQQM@28211|Alphaproteobacteria,47F0K@766|Rickettsiales	766|Rickettsiales	T	response regulator containing a CheY-like receiver domain and a GGDEF domain	pleD	-	2.7.7.65	ko:K02488	ko02020,ko04112,map02020,map04112	M00511	R08057	-	ko00000,ko00001,ko00002,ko01000,ko02022	-	-	-	GGDEF,Response_reg
k59_53458_1	1307759.JOMJ01000004_gene2986	0.000156	45.4	COG1044@1|root,COG1044@2|Bacteria,1MUX6@1224|Proteobacteria,42M4X@68525|delta/epsilon subdivisions,2WJJY@28221|Deltaproteobacteria,2M7TA@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxD	GO:0003674,GO:0003824,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	2.3.1.191	ko:K02536	ko00540,ko01100,map00540,map01100	M00060	R04550	RC00039,RC00166	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hexapep,Hexapep_2,LpxD
k59_53458_2	1121439.dsat_1245	7.55e-56	179.0	COG0764@1|root,COG0764@2|Bacteria,1RH2T@1224|Proteobacteria,42SCN@68525|delta/epsilon subdivisions,2WP3E@28221|Deltaproteobacteria,2MCBA@213115|Desulfovibrionales	28221|Deltaproteobacteria	I	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs	fabZ	-	4.2.1.59	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121	RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FabA
k59_53471_1	388401.RB2150_12956	1.99e-101	303.0	COG3839@1|root,COG3839@2|Bacteria,1MU7W@1224|Proteobacteria,2TQNF@28211|Alphaproteobacteria,3ZGB8@58840|unclassified Rhodobacteraceae	28211|Alphaproteobacteria	G	COG3839 ABC-type sugar transport systems, ATPase components	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,TOBE_2
k59_136863_1	1121405.dsmv_2056	9.1e-54	185.0	2C2F5@1|root,32WND@2|Bacteria,1ND6R@1224|Proteobacteria,42Q4T@68525|delta/epsilon subdivisions,2WK9F@28221|Deltaproteobacteria,2MHXS@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_8014_1	983920.Y88_1933	1.4e-46	162.0	COG2070@1|root,COG2070@2|Bacteria,1MWPC@1224|Proteobacteria,2TQRT@28211|Alphaproteobacteria,2K0DQ@204457|Sphingomonadales	204457|Sphingomonadales	S	2-nitropropane dioxygenase	-	-	1.3.1.9	ko:K02371	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00083	R04429,R04724,R04955,R04958,R04961,R04966,R04969,R07765	RC00052,RC00076	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	NMO,ThiG
k59_152006_1	1121405.dsmv_2105	8.33e-111	337.0	COG0427@1|root,COG0454@1|root,COG0427@2|Bacteria,COG0456@2|Bacteria,1MUGE@1224|Proteobacteria,42MHC@68525|delta/epsilon subdivisions,2WINZ@28221|Deltaproteobacteria,2MI87@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM Acetyl-CoA hydrolase transferase	-	-	-	-	-	-	-	-	-	-	-	-	AcetylCoA_hyd_C,AcetylCoA_hydro,Acetyltransf_1,Acetyltransf_3
k59_121707_1	945713.IALB_1713	4.79e-45	159.0	COG0859@1|root,COG0859@2|Bacteria	2|Bacteria	M	ADP-heptose-lipopolysaccharide heptosyltransferase activity	-	-	-	ko:K02843	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
k59_61137_1	1121405.dsmv_3635	6.64e-62	207.0	COG1021@1|root,COG1021@2|Bacteria,1NSN8@1224|Proteobacteria,42NP6@68525|delta/epsilon subdivisions,2WIZK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	Q	2,3-dihydroxybenzoate-AMP ligase	-	-	2.7.7.58,6.3.2.14	ko:K02363	ko01053,ko01110,ko01130,map01053,map01110,map01130	-	R07644	RC00162,RC03046	ko00000,ko00001,ko01000,ko01008	-	-	-	AMP-binding,AMP-binding_C
k59_167106_1	1128421.JAGA01000002_gene1053	3.07e-26	103.0	COG1514@1|root,COG1514@2|Bacteria,2NPRT@2323|unclassified Bacteria	2|Bacteria	J	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester	ligT	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008104,GO:0008150,GO:0009966,GO:0010646,GO:0010738,GO:0023051,GO:0033036,GO:0034237,GO:0044424,GO:0044444,GO:0044464,GO:0048583,GO:0050789,GO:0050794,GO:0051018,GO:0051179,GO:0065007,GO:1902531	3.1.4.58	ko:K01975	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	LigT_PEase
k59_23132_1	1121405.dsmv_0690	7.31e-65	212.0	COG3829@1|root,COG4585@1|root,COG3829@2|Bacteria,COG4585@2|Bacteria,1MWPN@1224|Proteobacteria,42RUN@68525|delta/epsilon subdivisions,2WNJZ@28221|Deltaproteobacteria,2MPS9@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE4,HAMP,HATPase_c,HisKA_3,PAS_3,PAS_4,PAS_9
k59_114081_1	1265505.ATUG01000003_gene519	4.07e-71	235.0	COG3829@1|root,COG4191@1|root,COG3829@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42NFY@68525|delta/epsilon subdivisions,2WKC0@28221|Deltaproteobacteria,2MN70@213118|Desulfobacterales	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_9
k59_212585_1	289376.THEYE_A0677	1.4e-12	67.4	COG2804@1|root,COG2804@2|Bacteria,3J0XR@40117|Nitrospirae	40117|Nitrospirae	NU	Type II/IV secretion system protein	-	-	-	ko:K02454,ko:K02652	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSE,T2SSE_N
k59_212585_2	879212.DespoDRAFT_02312	8.93e-52	176.0	COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,42NES@68525|delta/epsilon subdivisions,2WJ0V@28221|Deltaproteobacteria,2MHWD@213118|Desulfobacterales	28221|Deltaproteobacteria	NU	type II secretion system	pilC	-	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
k59_235451_1	56780.SYN_00464	1.15e-44	156.0	28IH6@1|root,2Z8IF@2|Bacteria,1R4Z0@1224|Proteobacteria,42R34@68525|delta/epsilon subdivisions,2WN49@28221|Deltaproteobacteria,2MRQ5@213462|Syntrophobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_61623_1	1121405.dsmv_3129	2.22e-115	344.0	COG0499@1|root,COG0499@2|Bacteria,1MUQ2@1224|Proteobacteria,42M83@68525|delta/epsilon subdivisions,2WIZE@28221|Deltaproteobacteria,2MI5G@213118|Desulfobacterales	28221|Deltaproteobacteria	H	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine	ahcY	GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
k59_160122_1	857087.Metme_1336	1.15e-48	173.0	COG0367@1|root,COG0367@2|Bacteria,1MW4E@1224|Proteobacteria,1RQ7D@1236|Gammaproteobacteria,1XDVZ@135618|Methylococcales	135618|Methylococcales	F	PFAM Asparagine synthase	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
k59_129694_1	1121405.dsmv_0694	3.66e-60	201.0	COG4260@1|root,COG4260@2|Bacteria,1MXTD@1224|Proteobacteria,42P7D@68525|delta/epsilon subdivisions,2WJ6S@28221|Deltaproteobacteria,2MIXK@213118|Desulfobacterales	28221|Deltaproteobacteria	S	PFAM SPFH domain Band 7 family	-	-	-	-	-	-	-	-	-	-	-	-	Band_7_1,DZR,SHOCT,zinc_ribbon_2
k59_747_1	1340434.AXVA01000035_gene92	2.65e-24	106.0	COG3829@1|root,COG3829@2|Bacteria,1TP0E@1239|Firmicutes,4HC5M@91061|Bacilli,1ZB0M@1386|Bacillus	91061|Bacilli	KT	COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains	-	-	-	ko:K06714	-	-	-	-	ko00000,ko03000	-	-	-	HTH_8,PAS,PAS_4,PAS_9,Sigma54_activat
k59_84165_1	246194.CHY_1730	2.19e-44	159.0	COG2368@1|root,COG2368@2|Bacteria,1TQ70@1239|Firmicutes,248RP@186801|Clostridia,42I6F@68295|Thermoanaerobacterales	186801|Clostridia	Q	4-hydroxyphenylacetate 3-hydroxylase C terminal	-	-	1.14.14.9,4.2.1.120,5.3.3.3	ko:K00483,ko:K14534	ko00350,ko00650,ko00720,ko01100,ko01120,ko01200,ko01220,map00350,map00650,map00720,map01100,map01120,map01200,map01220	M00374,M00375	R02698,R03031,R03299,R10782	RC00046,RC01857,RC03277	ko00000,ko00001,ko00002,ko01000	-	-	-	HpaB,HpaB_N
k59_46283_1	1408428.JNJP01000001_gene3269	8.69e-56	181.0	COG1014@1|root,COG1014@2|Bacteria,1RBZA@1224|Proteobacteria,42QT3@68525|delta/epsilon subdivisions,2X6H9@28221|Deltaproteobacteria,2MH2Y@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	Pyruvate ferredoxin/flavodoxin oxidoreductase	-	-	1.2.7.8	ko:K00180	-	-	-	-	br01601,ko00000,ko01000	-	-	-	POR
k59_144857_1	218284.CCDN010000001_gene579	6.54e-08	54.3	COG3547@1|root,COG3547@2|Bacteria,1V427@1239|Firmicutes,4HGY6@91061|Bacilli,1ZERT@1386|Bacillus	91061|Bacilli	L	PFAM transposase IS116 IS110 IS902 family	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_53889_1	420246.GTNG_2362	7.76e-15	74.3	COG1003@1|root,COG1003@2|Bacteria,1TPK9@1239|Firmicutes,4HB80@91061|Bacilli,1WEFM@129337|Geobacillus	91061|Bacilli	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvPB	-	1.4.4.2	ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	-	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko01000	-	-	-	GDC-P
k59_15965_1	234267.Acid_1263	2.33e-65	212.0	COG1063@1|root,COG1063@2|Bacteria,3Y2H8@57723|Acidobacteria	57723|Acidobacteria	E	PFAM Alcohol dehydrogenase	-	-	1.1.1.14	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	M00014	R00875,R01896	RC00085,RC00102	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N
k59_15967_1	1121422.AUMW01000010_gene1159	4.23e-23	99.4	COG0001@1|root,COG0001@2|Bacteria,1TPNH@1239|Firmicutes,248II@186801|Clostridia,26072@186807|Peptococcaceae	186801|Clostridia	H	PFAM Aminotransferase class-III	hemL	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
k59_15967_2	96561.Dole_0628	2.25e-11	60.1	COG5336@1|root,COG5336@2|Bacteria,1NHIS@1224|Proteobacteria,42VWC@68525|delta/epsilon subdivisions,2WS5S@28221|Deltaproteobacteria,2MKV4@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter	-	-	-	ko:K02116	-	-	-	-	ko00000,ko00194	3.A.2.1	-	-	ATPase_gene1
k59_91768_1	868864.Dester_0424	5.23e-55	185.0	COG0151@1|root,COG0151@2|Bacteria,2G3J3@200783|Aquificae	200783|Aquificae	F	Belongs to the GARS family	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	GARS_A,GARS_C,GARS_N
k59_31153_1	446469.Sked_35990	1.04e-06	57.4	COG3591@1|root,COG3591@2|Bacteria,2GJVS@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the glycosyl hydrolase 3 family	-	-	-	-	-	-	-	-	-	-	-	-	Trypsin,Trypsin_2
k59_205617_2	1121434.AULY01000007_gene1331	4.92e-16	79.7	COG0437@1|root,COG0437@2|Bacteria,1MU1B@1224|Proteobacteria,42M97@68525|delta/epsilon subdivisions,2WJB4@28221|Deltaproteobacteria,2M9HU@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein	hmcB	-	-	-	-	-	-	-	-	-	-	-	Fer4_11,Fer4_4,Fer4_7
k59_53890_1	1304885.AUEY01000003_gene496	6.86e-28	100.0	COG1773@1|root,COG1773@2|Bacteria,1N731@1224|Proteobacteria,42VC4@68525|delta/epsilon subdivisions,2WRDM@28221|Deltaproteobacteria,2MKVE@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Rubredoxin	rub	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	-	-	-	-	-	-	-	-	-	Rubredoxin
k59_53890_2	357804.Ping_3444	2.8e-42	142.0	COG0251@1|root,COG0251@2|Bacteria,1MZ3J@1224|Proteobacteria,1S5XS@1236|Gammaproteobacteria,2QJ31@267894|Psychromonadaceae	1236|Gammaproteobacteria	J	Endoribonuclease L-PSP	-	-	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP
k59_53890_3	335543.Sfum_1613	2.48e-90	275.0	COG0037@1|root,COG0037@2|Bacteria,1MW5Q@1224|Proteobacteria,42MMC@68525|delta/epsilon subdivisions,2WN12@28221|Deltaproteobacteria,2MQHR@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	PP-loop family	ttcA	-	-	ko:K14058	-	-	-	-	ko00000,ko03016	-	-	-	ATP_bind_3
k59_53890_5	335543.Sfum_1766	9.19e-34	128.0	COG2896@1|root,COG2896@2|Bacteria,1MXMH@1224|Proteobacteria,42NTM@68525|delta/epsilon subdivisions,2WKIQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
k59_91769_2	1139219.I569_01661	2.08e-05	53.9	28KEB@1|root,2ZA0K@2|Bacteria,1V14E@1239|Firmicutes,4HNU7@91061|Bacilli,4B291@81852|Enterococcaceae	91061|Bacilli	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_15971_1	264732.Moth_0254	5.6e-70	236.0	COG0210@1|root,COG1379@1|root,COG0210@2|Bacteria,COG1379@2|Bacteria,1TPSU@1239|Firmicutes,247RM@186801|Clostridia,42EUR@68295|Thermoanaerobacterales	186801|Clostridia	L	PFAM UvrD REP helicase	-	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
k59_197965_1	439235.Dalk_5173	7.68e-49	176.0	COG2204@1|root,COG4191@1|root,COG2204@2|Bacteria,COG4191@2|Bacteria,1R891@1224|Proteobacteria,42P2C@68525|delta/epsilon subdivisions,2WJZT@28221|Deltaproteobacteria,2MIG9@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
k59_235931_1	706587.Desti_0693	6.39e-37	140.0	COG1013@1|root,COG1014@1|root,COG1013@2|Bacteria,COG1014@2|Bacteria,1R5BF@1224|Proteobacteria,42MD3@68525|delta/epsilon subdivisions,2WJQ0@28221|Deltaproteobacteria,2MR0N@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	ferredoxin oxidoreductase beta subunit	korB	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
k59_205622_1	688245.CtCNB1_4328	2.55e-39	146.0	COG0683@1|root,COG0683@2|Bacteria,1MV5T@1224|Proteobacteria,2VI33@28216|Betaproteobacteria,4A9NB@80864|Comamonadaceae	28216|Betaproteobacteria	E	Amino acid amide ABC transporter substrate-binding protein, HAAT family	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
k59_114500_1	396588.Tgr7_2590	5.46e-06	55.1	COG0425@1|root,COG2391@1|root,COG0425@2|Bacteria,COG2391@2|Bacteria	2|Bacteria	O	sulfur carrier activity	tusA-2	GO:0008150,GO:0009987,GO:0019725,GO:0042592,GO:0048878,GO:0055082,GO:0065007,GO:0065008	-	ko:K04085,ko:K07112	ko04122,map04122	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	HTH_20,HTH_5,Sulf_transp,TusA
k59_213044_1	1450525.JATV01000001_gene2502	3.19e-51	174.0	COG0628@1|root,COG0628@2|Bacteria,4NN3B@976|Bacteroidetes,1HYEH@117743|Flavobacteriia,2NUR6@237|Flavobacterium	976|Bacteroidetes	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
k59_31173_1	1304885.AUEY01000002_gene380	1.39e-14	74.7	COG3168@1|root,COG3168@2|Bacteria,1N39F@1224|Proteobacteria,42U30@68525|delta/epsilon subdivisions,2WRT8@28221|Deltaproteobacteria,2MPRF@213118|Desulfobacterales	28221|Deltaproteobacteria	NU	Pilus assembly protein, PilP	-	-	-	ko:K02665	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilP
k59_106996_1	1423807.BACO01000036_gene1015	6.78e-07	57.4	COG0477@1|root,COG2814@2|Bacteria,1TRUT@1239|Firmicutes,4HEF9@91061|Bacilli,3FC49@33958|Lactobacillaceae	91061|Bacilli	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_3
k59_122152_1	335543.Sfum_0379	1.59e-97	296.0	COG1541@1|root,COG1541@2|Bacteria,1MXF5@1224|Proteobacteria,42MZA@68525|delta/epsilon subdivisions,2WIUC@28221|Deltaproteobacteria,2MRDJ@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)	-	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C_2
k59_144886_1	945713.IALB_2289	1.42e-13	71.2	COG0589@1|root,COG0589@2|Bacteria	2|Bacteria	T	AMP binding	-	-	-	-	-	-	-	-	-	-	-	-	Usp
k59_144888_1	1121403.AUCV01000029_gene2659	1.69e-46	168.0	COG1075@1|root,COG1075@2|Bacteria,1R5PF@1224|Proteobacteria,43BHB@68525|delta/epsilon subdivisions,2X6VQ@28221|Deltaproteobacteria,2MMMX@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Alpha/beta hydrolase of unknown function (DUF915)	-	-	-	-	-	-	-	-	-	-	-	-	DUF915
k59_46305_1	697282.Mettu_2809	3.28e-41	148.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,1RX1K@1236|Gammaproteobacteria,1XGJU@135618|Methylococcales	135618|Methylococcales	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
k59_8439_1	330214.NIDE2332	3.66e-50	178.0	COG0028@1|root,COG0028@2|Bacteria,3J0D6@40117|Nitrospirae	2|Bacteria	H	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
k59_114519_1	335543.Sfum_0853	5.3e-96	295.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,2MR37@213462|Syntrophobacterales	28221|Deltaproteobacteria	K	two component, sigma54 specific, transcriptional regulator, Fis family	-	-	-	ko:K02481	-	-	-	-	ko00000,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
k59_31180_1	269799.Gmet_1848	1.06e-94	291.0	COG1570@1|root,COG1570@2|Bacteria,1MUA4@1224|Proteobacteria,42MSB@68525|delta/epsilon subdivisions,2WJI6@28221|Deltaproteobacteria,43TW2@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseA	-	3.1.11.6	ko:K03601	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
k59_8446_1	56780.SYN_01010	1.21e-57	197.0	COG1538@1|root,COG1538@2|Bacteria,1PTZ6@1224|Proteobacteria,42RK2@68525|delta/epsilon subdivisions,2WNMB@28221|Deltaproteobacteria,2MS0Y@213462|Syntrophobacterales	28221|Deltaproteobacteria	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
k59_220887_1	706587.Desti_2860	2.74e-75	236.0	COG0533@1|root,COG0533@2|Bacteria,1MU6S@1224|Proteobacteria,42MHX@68525|delta/epsilon subdivisions,2WIKS@28221|Deltaproteobacteria,2MQ83@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
k59_205630_1	439235.Dalk_2731	1.44e-110	331.0	COG2368@1|root,COG2368@2|Bacteria,1PEQG@1224|Proteobacteria,42NUH@68525|delta/epsilon subdivisions,2WISE@28221|Deltaproteobacteria,2MI4T@213118|Desulfobacterales	28221|Deltaproteobacteria	Q	PFAM 4-hydroxyphenylacetate 3-hydroxylase N terminal	-	-	4.2.1.120,5.3.3.3	ko:K14534	ko00650,ko00720,ko01100,ko01120,ko01200,map00650,map00720,map01100,map01120,map01200	M00374,M00375	R03031,R10782	RC01857,RC03277	ko00000,ko00001,ko00002,ko01000	-	-	-	HpaB,HpaB_N
k59_175277_1	945543.VIBR0546_06757	2.04e-33	129.0	COG4670@1|root,COG4670@2|Bacteria,1MUJW@1224|Proteobacteria,1RP80@1236|Gammaproteobacteria,1Y251@135623|Vibrionales	135623|Vibrionales	I	CoA transferase having broad substrate specificity for short-chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons	-	-	2.8.3.1	ko:K01026	ko00620,ko00640,ko00643,ko01100,ko01120,map00620,map00640,map00643,map01100,map01120	-	R00928,R01449,R05508	RC00012,RC00014,RC00137	ko00000,ko00001,ko01000	-	-	-	CoA_trans
k59_167603_1	338966.Ppro_2399	8.62e-190	550.0	COG0317@1|root,COG0317@2|Bacteria,1MU44@1224|Proteobacteria,42M6W@68525|delta/epsilon subdivisions,2WIZF@28221|Deltaproteobacteria,43SZI@69541|Desulfuromonadales	28221|Deltaproteobacteria	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	relA	-	2.7.6.5	ko:K00951	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
k59_205635_1	1121405.dsmv_3059	1.43e-53	188.0	COG0751@1|root,COG0751@2|Bacteria,1MV2F@1224|Proteobacteria,42M6A@68525|delta/epsilon subdivisions,2WJIT@28221|Deltaproteobacteria,2MHVB@213118|Desulfobacterales	28221|Deltaproteobacteria	J	glycyl-tRNA synthetase, beta	glyS	-	6.1.1.14	ko:K01879	ko00970,map00970	M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_1,tRNA_synt_2f
k59_107021_2	585394.RHOM_09450	2.07e-11	60.8	COG0251@1|root,COG0251@2|Bacteria,1V6HG@1239|Firmicutes,24J8Y@186801|Clostridia	186801|Clostridia	J	endoribonuclease L-PSP	TdcF	-	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP
k59_160213_1	272557.APE_1045.1	2.4e-30	120.0	COG0281@1|root,arCOG01331@2157|Archaea,2XPXF@28889|Crenarchaeota	28889|Crenarchaeota	O	Belongs to the peptidase M48B family	htpX	-	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	Peptidase_M48
k59_129744_1	1121405.dsmv_3678	1.83e-22	91.7	COG0071@1|root,COG0071@2|Bacteria,1N7C7@1224|Proteobacteria,42U0T@68525|delta/epsilon subdivisions,2WQ88@28221|Deltaproteobacteria,2MPZC@213118|Desulfobacterales	28221|Deltaproteobacteria	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
k59_117496_1	1001530.BACE01000011_gene2109	5.98e-37	132.0	COG3184@1|root,COG3184@2|Bacteria,1N7UG@1224|Proteobacteria,1SBGC@1236|Gammaproteobacteria,1XYZC@135623|Vibrionales	135623|Vibrionales	S	Uncharacterized protein conserved in bacteria (DUF2059)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2059
k59_201444_1	1121403.AUCV01000002_gene520	1.44e-20	87.4	2CP6B@1|root,32SIH@2|Bacteria,1N48E@1224|Proteobacteria,42TWR@68525|delta/epsilon subdivisions,2WPZM@28221|Deltaproteobacteria,2MKFT@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Oxaloacetate decarboxylase, gamma chain	-	-	-	-	-	-	-	-	-	-	-	-	OAD_gamma
k59_156567_2	877455.Metbo_0865	5.05e-18	85.9	COG0451@1|root,arCOG01369@2157|Archaea,2XTTP@28890|Euryarchaeota,23NT5@183925|Methanobacteria	183925|Methanobacteria	M	PFAM NAD dependent epimerase dehydratase family	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
k59_187097_1	935261.JAGL01000001_gene1813	2.4e-13	75.1	COG0747@1|root,COG0747@2|Bacteria,1MUZH@1224|Proteobacteria,2TR1D@28211|Alphaproteobacteria,43N5M@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02033,ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
k59_26980_2	335543.Sfum_1583	4.25e-54	174.0	COG0203@1|root,COG0203@2|Bacteria,1RCWN@1224|Proteobacteria,42SBD@68525|delta/epsilon subdivisions,2WP9P@28221|Deltaproteobacteria,2MQIR@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	PFAM ribosomal protein L17	rplQ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02879	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L17
k59_58005_1	1237149.C900_05514	2.71e-104	314.0	COG0626@1|root,COG0626@2|Bacteria,4PKE6@976|Bacteroidetes,47KC8@768503|Cytophagia	976|Bacteroidetes	E	Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide	-	-	2.5.1.48,4.4.1.8	ko:K01739,ko:K01760	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017	R00782,R00999,R01286,R01288,R02408,R02508,R03217,R03260,R04941,R04944,R04945,R04946	RC00020,RC00056,RC00069,RC00382,RC00420,RC00488,RC00710,RC01245,RC02303,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000	-	-	-	Cys_Met_Meta_PP
k59_12682_1	909663.KI867149_gene3455	2.29e-50	185.0	COG0574@1|root,COG3848@1|root,COG0574@2|Bacteria,COG3848@2|Bacteria,1MXBU@1224|Proteobacteria,42M59@68525|delta/epsilon subdivisions,2WIUK@28221|Deltaproteobacteria,2MR7V@213462|Syntrophobacterales	28221|Deltaproteobacteria	G	Pyruvate phosphate dikinase, PEP/pyruvate binding domain	-	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PPDK_N
k59_201999_1	331678.Cphamn1_1659	1.54e-21	88.2	COG1661@1|root,COG1661@2|Bacteria,1FF1P@1090|Chlorobi	1090|Chlorobi	S	Domain of unknown function (DUF296)	-	-	-	-	-	-	-	-	-	-	-	-	DUF296
k59_201999_2	1173023.KE650771_gene4342	2.95e-05	46.6	COG3240@1|root,COG4625@1|root,COG3240@2|Bacteria,COG4625@2|Bacteria,1G2WT@1117|Cyanobacteria,1JKJE@1189|Stigonemataceae	1117|Cyanobacteria	I	Autotransporter beta-domain	-	-	-	ko:K12686	-	-	-	-	ko00000,ko02000,ko02044	1.B.12.8	-	-	Autotransporter,Lipase_GDSL
k59_141442_1	363253.LI0383	6.51e-51	166.0	COG0233@1|root,COG0233@2|Bacteria,1N66T@1224|Proteobacteria,42NAA@68525|delta/epsilon subdivisions,2WNMN@28221|Deltaproteobacteria,2M8XC@213115|Desulfovibrionales	28221|Deltaproteobacteria	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
k59_141442_2	596151.DesfrDRAFT_2331	4.25e-49	163.0	COG0528@1|root,COG0528@2|Bacteria,1MV3N@1224|Proteobacteria,42M3X@68525|delta/epsilon subdivisions,2WJDF@28221|Deltaproteobacteria,2M9TD@213115|Desulfovibrionales	28221|Deltaproteobacteria	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
k59_133826_1	1469245.JFBG01000011_gene839	1.6e-73	243.0	COG0747@1|root,COG0747@2|Bacteria,1MUZH@1224|Proteobacteria	1224|Proteobacteria	E	ABC-Type Dipeptide Transport System Periplasmic Component	appA	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
k59_3933_1	933262.AXAM01000017_gene3132	1.84e-08	61.6	COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,1MUKF@1224|Proteobacteria,42N3S@68525|delta/epsilon subdivisions,2WJ5P@28221|Deltaproteobacteria,2MI3T@213118|Desulfobacterales	28221|Deltaproteobacteria	S	DNA internalization-related competence protein ComEC Rec2	-	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131,Lactamase_B
k59_148220_2	96561.Dole_2251	3.85e-34	127.0	COG0437@1|root,COG0437@2|Bacteria,1MU1B@1224|Proteobacteria,42M97@68525|delta/epsilon subdivisions,2WJB4@28221|Deltaproteobacteria,2MJB7@213118|Desulfobacterales	28221|Deltaproteobacteria	C	4Fe-4S dicluster domain	hmcB	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Fer4_11,Fer4_4,Fer4_7
k59_26988_1	177437.HRM2_09060	2.4e-47	169.0	COG1032@1|root,COG1032@2|Bacteria,1R52J@1224|Proteobacteria,42P9G@68525|delta/epsilon subdivisions,2WKFU@28221|Deltaproteobacteria,2MIVS@213118|Desulfobacterales	28221|Deltaproteobacteria	C	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
k59_65023_1	411468.CLOSCI_03453	1.15e-59	208.0	COG0210@1|root,COG1379@1|root,COG0210@2|Bacteria,COG1379@2|Bacteria,1TT86@1239|Firmicutes,247QE@186801|Clostridia,21XY2@1506553|Lachnoclostridium	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	UvrD-helicase,UvrD_C
k59_103453_1	96561.Dole_0660	4.44e-52	176.0	COG3039@1|root,COG3039@2|Bacteria,1QQ9Q@1224|Proteobacteria,42S7X@68525|delta/epsilon subdivisions,2WNJ2@28221|Deltaproteobacteria,2MJG4@213118|Desulfobacterales	28221|Deltaproteobacteria	L	PFAM transposase IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DUF772
k59_193774_1	933262.AXAM01000062_gene948	1.67e-67	229.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2WJN5@28221|Deltaproteobacteria,2MIEI@213118|Desulfobacterales	28221|Deltaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_126327_1	1125863.JAFN01000001_gene77	1.42e-32	120.0	COG4729@1|root,COG4729@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF1850)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1850
k59_126327_2	1125863.JAFN01000001_gene76	6.52e-62	209.0	COG4666@1|root,COG4666@2|Bacteria,1MUNB@1224|Proteobacteria,42MEV@68525|delta/epsilon subdivisions,2WK2S@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	TIGRFAM TRAP transporter, 4TM 12TM fusion protein	-	-	-	-	-	-	-	-	-	-	-	-	DctM
k59_232588_1	1449058.JQKT01000007_gene1717	3.58e-05	52.4	COG4972@1|root,COG4972@2|Bacteria,2IBNF@201174|Actinobacteria,4FMGF@85023|Microbacteriaceae	201174|Actinobacteria	NU	Type IV pilus assembly protein PilM;	pilM	-	-	ko:K02662	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilM_2
k59_65025_1	666685.R2APBS1_3900	3.67e-37	140.0	COG3666@1|root,COG3666@2|Bacteria,1N3QR@1224|Proteobacteria,1RR2W@1236|Gammaproteobacteria,1X8XV@135614|Xanthomonadales	135614|Xanthomonadales	L	PFAM Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_6,DUF772
k59_133837_1	716541.ECL_01999	9.4e-23	99.4	COG0329@1|root,COG0329@2|Bacteria,1R4AY@1224|Proteobacteria,1RRPJ@1236|Gammaproteobacteria,3X3JQ@547|Enterobacter	1236|Gammaproteobacteria	H	Dihydrodipicolinate synthetase family	-	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
k59_12693_1	335543.Sfum_3497	5.23e-27	114.0	COG1178@1|root,COG1178@2|Bacteria,1MWEV@1224|Proteobacteria,42TI5@68525|delta/epsilon subdivisions,2WQR8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02011	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	BPD_transp_1
k59_126342_1	169963.lmo0066	4.87e-33	130.0	COG5585@1|root,COG5585@2|Bacteria,1V069@1239|Firmicutes,4HD0D@91061|Bacilli,26JXZ@186820|Listeriaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	ADPrib_exo_Tox,PT-TG
k59_156589_1	1121405.dsmv_1162	3.49e-79	243.0	COG0682@1|root,COG0682@2|Bacteria,1MVE3@1224|Proteobacteria,42M2I@68525|delta/epsilon subdivisions,2WMSH@28221|Deltaproteobacteria,2MPU8@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
k59_12705_1	543728.Vapar_4891	4.95e-38	135.0	COG0745@1|root,COG0745@2|Bacteria,1MY3D@1224|Proteobacteria,2VIYR@28216|Betaproteobacteria,4ACV9@80864|Comamonadaceae	28216|Betaproteobacteria	K	Two component transcriptional regulator	-	-	-	ko:K11329	ko02020,map02020	M00467	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
k59_224287_1	1408473.JHXO01000009_gene3404	7.84e-77	253.0	COG1615@1|root,COG1615@2|Bacteria	2|Bacteria	S	Uncharacterised protein family (UPF0182)	-	GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	ko:K09118	-	-	-	-	ko00000	-	-	-	UPF0182
k59_58047_1	96561.Dole_0333	7.83e-28	111.0	COG4972@1|root,COG4972@2|Bacteria,1MX8P@1224|Proteobacteria,42M36@68525|delta/epsilon subdivisions,2WJFJ@28221|Deltaproteobacteria,2MID0@213118|Desulfobacterales	28221|Deltaproteobacteria	NU	TIGRFAM type IV pilus assembly protein PilM	pilM	-	-	ko:K02662	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilM_2
k59_19638_1	1304885.AUEY01000068_gene1406	6.05e-58	200.0	COG2183@1|root,COG2183@2|Bacteria,1MUA7@1224|Proteobacteria,42M9U@68525|delta/epsilon subdivisions,2WJ4X@28221|Deltaproteobacteria,2MI7A@213118|Desulfobacterales	28221|Deltaproteobacteria	K	RNA binding S1 domain protein	tex	-	-	ko:K06959	-	-	-	-	ko00000	-	-	-	HHH_3,S1,Tex_N,Tex_YqgF
k59_239312_1	316067.Geob_3374	3.95e-67	223.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,42M51@68525|delta/epsilon subdivisions,2WIPP@28221|Deltaproteobacteria,43TCZ@69541|Desulfuromonadales	28221|Deltaproteobacteria	NU	General secretory system II, protein E domain protein	pilB	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE,T2SSE_N,cNMP_binding
k59_42160_1	485916.Dtox_0342	5.22e-36	131.0	COG3640@1|root,COG3640@2|Bacteria,1V308@1239|Firmicutes,24H11@186801|Clostridia	186801|Clostridia	D	CobQ/CobB/MinD/ParA nucleotide binding domain	-	-	-	ko:K07321	-	-	-	-	ko00000	-	-	-	CbiA
k59_224289_1	391735.Veis_4536	1.13e-29	120.0	COG3552@1|root,COG3552@2|Bacteria,1MUHH@1224|Proteobacteria,2VNH5@28216|Betaproteobacteria,4ACDG@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM VWA containing CoxE family protein	-	-	-	ko:K07161	-	-	-	-	ko00000	-	-	-	VWA_CoxE
k59_95804_1	522772.Dacet_1039	1.94e-46	169.0	COG3604@1|root,COG3604@2|Bacteria,2GEZF@200930|Deferribacteres	200930|Deferribacteres	KT	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	-	ko:K02584	ko02020,map02020	-	-	-	ko00000,ko00001,ko03000	-	-	-	GAF,GAF_2,HTH_8,Sigma54_activat
k59_224290_1	1121405.dsmv_1097	1.67e-91	278.0	COG0484@1|root,COG0484@2|Bacteria,1R9Y3@1224|Proteobacteria,42RBH@68525|delta/epsilon subdivisions,2WP1M@28221|Deltaproteobacteria,2MK1W@213118|Desulfobacterales	28221|Deltaproteobacteria	O	DnaJ molecular chaperone homology domain	-	-	-	ko:K05516	-	-	-	-	ko00000,ko03036,ko03110	-	-	-	DnaJ,DnaJ_C
k59_87971_1	96561.Dole_0550	1.87e-75	242.0	COG0459@1|root,COG0459@2|Bacteria,1MURR@1224|Proteobacteria,42M52@68525|delta/epsilon subdivisions,2WIRK@28221|Deltaproteobacteria,2MHPV@213118|Desulfobacterales	28221|Deltaproteobacteria	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	-	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
k59_58055_1	1167006.UWK_03489	8.76e-50	181.0	COG0769@1|root,COG0770@1|root,COG0769@2|Bacteria,COG0770@2|Bacteria,1QTSF@1224|Proteobacteria,43BV1@68525|delta/epsilon subdivisions,2X760@28221|Deltaproteobacteria,2MPKR@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	-	6.3.2.10,6.3.2.13	ko:K15792	ko00300,ko00550,map00300,map00550	-	R02788,R04617	RC00064,RC00090,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
k59_35282_1	211165.AJLN01000051_gene4893	4.48e-96	290.0	COG1335@1|root,COG1335@2|Bacteria,1G10P@1117|Cyanobacteria,1JHM2@1189|Stigonemataceae	1117|Cyanobacteria	Q	isochorismatase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_239326_2	56780.SYN_00123	2.73e-45	163.0	COG0111@1|root,COG0111@2|Bacteria,1MU5Z@1224|Proteobacteria,42M1C@68525|delta/epsilon subdivisions,2WIZQ@28221|Deltaproteobacteria,2MQZI@213462|Syntrophobacterales	28221|Deltaproteobacteria	EH	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic	-	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C,ACT
k59_87977_1	177437.HRM2_07450	1.4e-65	217.0	COG0427@1|root,COG1670@1|root,COG0427@2|Bacteria,COG1670@2|Bacteria,1MUGE@1224|Proteobacteria,42MHC@68525|delta/epsilon subdivisions,2WINZ@28221|Deltaproteobacteria,2MMNB@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Acetyl-CoA hydrolase/transferase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AcetylCoA_hyd_C,AcetylCoA_hydro,Acetyltransf_1
k59_126368_1	946483.Cenrod_1069	1.82e-18	92.8	COG0834@1|root,COG5001@1|root,COG0834@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,4A9PA@80864|Comamonadaceae	28216|Betaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS,PAS_4,PAS_8,PAS_9,SBP_bac_3
k59_239327_1	335543.Sfum_0364	9.92e-64	210.0	COG1061@1|root,COG1061@2|Bacteria,1QWMJ@1224|Proteobacteria,42NXF@68525|delta/epsilon subdivisions,2WJWA@28221|Deltaproteobacteria,2MRP4@213462|Syntrophobacterales	28221|Deltaproteobacteria	L	Type III restriction enzyme, res subunit	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,ResIII
k59_141484_1	1415630.U771_17995	5.08e-17	85.5	COG3666@1|root,COG3666@2|Bacteria,1N3QR@1224|Proteobacteria,1S01K@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	COG3666 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_6,DUF772
k59_80817_1	748247.AZKH_1723	5.52e-49	178.0	COG2176@1|root,COG5002@1|root,COG2176@2|Bacteria,COG5002@2|Bacteria,1QUVW@1224|Proteobacteria,2VHZ3@28216|Betaproteobacteria,2KUQR@206389|Rhodocyclales	206389|Rhodocyclales	L	DNA polymerase III	-	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	RNase_T
k59_156613_1	1120966.AUBU01000001_gene1039	2.1e-18	89.7	COG0642@1|root,COG5002@1|root,COG2205@2|Bacteria,COG5002@2|Bacteria,4NDXU@976|Bacteroidetes,47JK3@768503|Cytophagia	976|Bacteroidetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISMED2,AAA_16,GAF,GAF_2,HATPase_c,HisKA,Hpt,PAS_3,PAS_4,PAS_9,Pkinase,Response_reg,SpoIIE,Y_Y_Y
k59_42175_1	1232437.KL662015_gene1286	3.35e-91	278.0	COG1902@1|root,COG1902@2|Bacteria,1MVE0@1224|Proteobacteria,42PDA@68525|delta/epsilon subdivisions,2WK0K@28221|Deltaproteobacteria,2MIH5@213118|Desulfobacterales	28221|Deltaproteobacteria	C	NADH:flavin oxidoreductase / NADH oxidase family	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_FMN
k59_141488_1	1499967.BAYZ01000176_gene5693	2.62e-114	340.0	COG1012@1|root,COG1012@2|Bacteria	2|Bacteria	C	belongs to the aldehyde dehydrogenase family	-	-	1.2.1.67	ko:K21802	ko00627,ko01120,map00627,map01120	-	R05699	RC00075	ko00000,ko00001,ko01000	-	-	-	Aldedh
k59_110990_2	483219.LILAB_22900	4.41e-38	135.0	COG2840@1|root,COG2840@2|Bacteria,1RH34@1224|Proteobacteria,42TQG@68525|delta/epsilon subdivisions,2WQG8@28221|Deltaproteobacteria,2YW3V@29|Myxococcales	28221|Deltaproteobacteria	S	Smr domain	-	-	-	-	-	-	-	-	-	-	-	-	Smr
k59_156615_1	795359.TOPB45_1140	1.38e-16	82.8	COG0704@1|root,COG1392@1|root,COG0704@2|Bacteria,COG1392@2|Bacteria,2GGUJ@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	P	Protein of unknown function DUF47	-	-	-	-	-	-	-	-	-	-	-	-	PhoU,PhoU_div
k59_156615_2	876044.IMCC3088_2347	9.82e-08	53.9	COG0306@1|root,COG0306@2|Bacteria,1MVXK@1224|Proteobacteria,1RP0Q@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	phosphate transporter	pitA	GO:0003674,GO:0005215,GO:0005315,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0015291,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0035435,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661	-	ko:K03306	-	-	-	-	ko00000	2.A.20	-	-	PHO4
k59_163671_1	1265505.ATUG01000002_gene1644	4.18e-105	310.0	COG0226@1|root,COG0226@2|Bacteria,1MVXP@1224|Proteobacteria,42PP7@68525|delta/epsilon subdivisions,2WJ4T@28221|Deltaproteobacteria,2MJBR@213118|Desulfobacterales	28221|Deltaproteobacteria	P	PBP superfamily domain	-	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
k59_209726_1	335543.Sfum_2077	6.72e-39	142.0	COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,42P0M@68525|delta/epsilon subdivisions,2WJMC@28221|Deltaproteobacteria,2MR1W@213462|Syntrophobacterales	28221|Deltaproteobacteria	I	AMP-dependent synthetase and ligase	-	-	6.2.1.1,6.2.1.32	ko:K01895,ko:K08295	ko00010,ko00620,ko00627,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00627,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R00982,R01354	RC00004,RC00012,RC00043,RC00070,RC00174,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
k59_65076_1	335543.Sfum_1034	1.78e-66	214.0	COG1420@1|root,COG1420@2|Bacteria,1MVX4@1224|Proteobacteria,42MTI@68525|delta/epsilon subdivisions,2WIXW@28221|Deltaproteobacteria,2MR88@213462|Syntrophobacterales	28221|Deltaproteobacteria	K	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons	hrcA	-	-	ko:K03705	-	-	-	-	ko00000,ko03000	-	-	-	HrcA,HrcA_DNA-bdg
k59_117974_1	1207055.C100_11530	7.08e-06	55.5	COG0784@1|root,COG4191@1|root,COG0784@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2TQQ9@28211|Alphaproteobacteria,2K01C@204457|Sphingomonadales	204457|Sphingomonadales	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_9,Response_reg
k59_103481_1	1121405.dsmv_0133	4.02e-64	213.0	COG2203@1|root,COG4585@1|root,COG2203@2|Bacteria,COG4585@2|Bacteria,1MWPN@1224|Proteobacteria,42U4X@68525|delta/epsilon subdivisions,2WPU1@28221|Deltaproteobacteria,2MNE3@213118|Desulfobacterales	28221|Deltaproteobacteria	T	ATP-binding region ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3,PAS_4
k59_117975_1	933262.AXAM01000048_gene2584	1.03e-101	298.0	COG0264@1|root,COG0264@2|Bacteria,1MUS2@1224|Proteobacteria,42NNS@68525|delta/epsilon subdivisions,2WMS3@28221|Deltaproteobacteria,2MI7H@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
k59_193804_1	640511.BC1002_4561	9.31e-79	243.0	COG0411@1|root,COG0411@2|Bacteria,1MUTY@1224|Proteobacteria,2VI2N@28216|Betaproteobacteria,1K414@119060|Burkholderiaceae	28216|Betaproteobacteria	E	ABC transporter	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
k59_42187_1	1121405.dsmv_2189	4.88e-80	247.0	COG0535@1|root,COG0535@2|Bacteria,1MUQP@1224|Proteobacteria,42M55@68525|delta/epsilon subdivisions,2WIKM@28221|Deltaproteobacteria,2MJ60@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM Radical SAM domain protein	-	-	-	ko:K22227	-	-	-	-	ko00000	-	-	-	Fer4_12,Fer4_14,Radical_SAM,SPASM
k59_217271_1	518766.Rmar_0923	4.95e-70	236.0	COG1703@1|root,COG1884@1|root,COG2185@1|root,COG1703@2|Bacteria,COG1884@2|Bacteria,COG2185@2|Bacteria,4NFHX@976|Bacteroidetes,1FIM5@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	EI	ArgK protein	icmF	-	5.4.99.13	ko:K11942	-	-	-	-	ko00000,ko01000	-	-	-	ArgK,B12-binding,MM_CoA_mutase
k59_88439_1	644282.Deba_0019	1.72e-23	105.0	COG2203@1|root,COG2204@1|root,COG3829@1|root,COG4191@1|root,COG2203@2|Bacteria,COG2204@2|Bacteria,COG3829@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,43BKN@68525|delta/epsilon subdivisions,2X7ZK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,Response_reg
k59_187602_1	1280685.AUKC01000007_gene2380	2.42e-07	50.4	COG2747@1|root,COG2747@2|Bacteria,1VFH9@1239|Firmicutes,24QZ8@186801|Clostridia,4BZQS@830|Butyrivibrio	186801|Clostridia	KNU	Anti-sigma-28 factor, FlgM	flgM	-	-	ko:K02398	ko02020,ko02025,ko02026,ko02040,map02020,map02025,map02026,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FlgM
k59_138390_1	1265505.ATUG01000002_gene1807	1.55e-18	83.6	COG1740@1|root,COG1740@2|Bacteria,1MWAC@1224|Proteobacteria,42MI0@68525|delta/epsilon subdivisions,2WIW4@28221|Deltaproteobacteria,2MJ8Z@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Hydrogenase (NiFe) small subunit HydA	hydA	GO:0005575,GO:0005623,GO:0042597,GO:0044464	1.12.2.1,1.12.5.1,1.12.7.2,1.12.99.6	ko:K00534,ko:K05927,ko:K06282,ko:K18008	ko00633,ko01120,map00633,map01120	-	R00019,R08034	RC00250	ko00000,ko00001,ko01000	-	-	-	NiFe_hyd_SSU_C,Oxidored_q6,TAT_signal
k59_161163_1	335543.Sfum_0698	4.74e-14	75.9	COG0492@1|root,COG0492@2|Bacteria,1R82E@1224|Proteobacteria,42PSM@68525|delta/epsilon subdivisions,2WJYX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,Pyr_redox_3
k59_9460_1	588581.Cpap_1808	2.81e-23	102.0	COG1032@1|root,COG1032@2|Bacteria,1UYAF@1239|Firmicutes,24D1D@186801|Clostridia	186801|Clostridia	C	PFAM Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,DUF4070,Radical_SAM
k59_183664_1	211586.SO_4053	3.99e-33	133.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,2QAI3@267890|Shewanellaceae	1236|Gammaproteobacteria	NT	PFAM histidine kinase, HAMP region domain protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal,dCache_3
k59_39789_1	400668.Mmwyl1_4205	1.78e-27	113.0	COG3039@1|root,COG3039@2|Bacteria,1MVTU@1224|Proteobacteria,1RZGN@1236|Gammaproteobacteria,1XPAH@135619|Oceanospirillales	135619|Oceanospirillales	L	Transposase domain (DUF772)	-	-	-	-	-	-	-	-	-	-	-	-	DUF772
k59_107937_1	1996.JOFO01000002_gene5652	6e-15	78.6	COG0466@1|root,COG0466@2|Bacteria,2GK9D@201174|Actinobacteria,4EFM3@85012|Streptosporangiales	201174|Actinobacteria	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
k59_62590_1	1500890.JQNL01000001_gene3038	2.8e-12	68.9	COG3501@1|root,COG3501@2|Bacteria,1MU7Q@1224|Proteobacteria,1RMZS@1236|Gammaproteobacteria,1X542@135614|Xanthomonadales	135614|Xanthomonadales	S	type VI secretion system Vgr family protein	-	-	-	ko:K11904	ko03070,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	Phage_GPD
k59_168487_1	1380350.JIAP01000001_gene1562	4.45e-07	57.0	COG1309@1|root,COG1309@2|Bacteria,1MZ9E@1224|Proteobacteria,2U0MU@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_7,TetR_N
k59_54984_1	177437.HRM2_02770	6.91e-121	356.0	COG4177@1|root,COG4177@2|Bacteria,1MV66@1224|Proteobacteria,42M11@68525|delta/epsilon subdivisions,2WK66@28221|Deltaproteobacteria,2MI46@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
k59_39793_1	177437.HRM2_43550	2.91e-24	105.0	COG0784@1|root,COG2198@1|root,COG4936@1|root,COG5002@1|root,COG0784@2|Bacteria,COG2198@2|Bacteria,COG4936@2|Bacteria,COG5002@2|Bacteria,1NC9X@1224|Proteobacteria,43BU6@68525|delta/epsilon subdivisions,2X756@28221|Deltaproteobacteria,2MPK6@213118|Desulfobacterales	28221|Deltaproteobacteria	KT	Sensory domain found in PocR	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,PAS,PAS_4,PAS_8,PAS_9,PocR,Response_reg
k59_138411_1	1307759.JOMJ01000003_gene704	9.13e-33	130.0	COG1022@1|root,COG1022@2|Bacteria,1MU4D@1224|Proteobacteria,42N2G@68525|delta/epsilon subdivisions,2WIXB@28221|Deltaproteobacteria,2M8U6@213115|Desulfovibrionales	28221|Deltaproteobacteria	I	AMP-dependent synthetase and ligase	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
k59_198994_2	1121405.dsmv_3041	3.44e-64	214.0	COG0441@1|root,COG0441@2|Bacteria,1MUP2@1224|Proteobacteria,42M20@68525|delta/epsilon subdivisions,2WJ2N@28221|Deltaproteobacteria,2MI0Z@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD
k59_77819_1	987059.RBXJA2T_14221	1.22e-07	58.9	COG0577@1|root,COG0577@2|Bacteria,1MVCT@1224|Proteobacteria,2VJAI@28216|Betaproteobacteria,1KJGP@119065|unclassified Burkholderiales	28216|Betaproteobacteria	V	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
k59_62592_1	1122185.N792_07570	4.64e-13	77.8	COG0305@1|root,COG0305@2|Bacteria,1MUG9@1224|Proteobacteria,1RPM2@1236|Gammaproteobacteria,1X3P0@135614|Xanthomonadales	135614|Xanthomonadales	L	it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins	dnaB	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
k59_39804_1	1121430.JMLG01000016_gene372	2.86e-40	142.0	COG1196@1|root,COG1196@2|Bacteria	2|Bacteria	D	nuclear chromosome segregation	-	-	4.2.2.20,4.2.2.21	ko:K02026,ko:K03529,ko:K08961	-	M00207	-	-	ko00000,ko00002,ko01000,ko02000,ko03036	3.A.1.1	-	-	BPD_transp_1,Big_4,FIVAR,Laminin_G_3,Lyase_8,Lyase_8_C,Lyase_N,Lyase_catalyt,MS_channel,SMC_N
k59_39804_2	883158.HMPREF9140_00515	7.49e-05	45.8	COG2217@1|root,COG2217@2|Bacteria,4NERS@976|Bacteroidetes,2FNJA@200643|Bacteroidia	976|Bacteroidetes	P	copper-exporting ATPase	actP	-	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
k59_130785_1	177437.HRM2_20940	5.2e-37	140.0	COG4666@1|root,COG4666@2|Bacteria,1MUNB@1224|Proteobacteria,42MEV@68525|delta/epsilon subdivisions,2WK2S@28221|Deltaproteobacteria,2MIMQ@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF3394)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3394,DctM
k59_236877_1	1121405.dsmv_1000	4.9e-44	157.0	COG0621@1|root,COG0621@2|Bacteria,1MUCS@1224|Proteobacteria,42MN1@68525|delta/epsilon subdivisions,2WJ1H@28221|Deltaproteobacteria,2MI7N@213118|Desulfobacterales	28221|Deltaproteobacteria	J	MiaB-like tRNA modifying enzyme	mtaB	-	2.8.4.5	ko:K18707	-	-	R10649	RC00003,RC03221	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,UPF0004
k59_145895_1	1121405.dsmv_0484	7.19e-111	330.0	COG0162@1|root,COG0162@2|Bacteria,1MVUQ@1224|Proteobacteria,42N2A@68525|delta/epsilon subdivisions,2WIP6@28221|Deltaproteobacteria,2MI9Q@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
k59_191347_1	1167006.UWK_02139	4.93e-41	156.0	COG1032@1|root,COG1032@2|Bacteria,1NAY8@1224|Proteobacteria,42TR8@68525|delta/epsilon subdivisions,2WQC1@28221|Deltaproteobacteria,2MMMU@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
k59_62597_1	1121405.dsmv_0315	7.86e-84	258.0	COG1883@1|root,COG1883@2|Bacteria,1MV0G@1224|Proteobacteria,42MH1@68525|delta/epsilon subdivisions,2WJD7@28221|Deltaproteobacteria,2MIY0@213118|Desulfobacterales	28221|Deltaproteobacteria	C	TIGRFAM sodium ion-translocating decarboxylase, beta subunit	-	-	4.1.1.3	ko:K01572	ko00620,ko01100,map00620,map01100	-	R00217	RC00040	ko00000,ko00001,ko01000,ko02000	3.B.1.1.1	-	-	OAD_beta
k59_236879_1	706587.Desti_2661	1.39e-38	142.0	COG2006@1|root,COG2006@2|Bacteria,1RK6S@1224|Proteobacteria,42SZ3@68525|delta/epsilon subdivisions,2WP5C@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Domain of unknown function (DUF362)	-	-	-	-	-	-	-	-	-	-	-	-	DUF362
k59_168505_2	1123057.P872_13075	3.62e-37	131.0	COG4122@1|root,COG4122@2|Bacteria,4PBU1@976|Bacteroidetes,47WBZ@768503|Cytophagia	976|Bacteroidetes	S	O-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_3
k59_153696_1	880072.Desac_0493	1.76e-20	91.3	COG0457@1|root,COG0491@1|root,COG0457@2|Bacteria,COG0491@2|Bacteria,1NX55@1224|Proteobacteria,430IJ@68525|delta/epsilon subdivisions,2WVK3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
k59_153696_2	880072.Desac_0501	1.77e-21	94.0	COG2202@1|root,COG2204@1|root,COG3290@1|root,COG2202@2|Bacteria,COG2204@2|Bacteria,COG3290@2|Bacteria,1MU0N@1224|Proteobacteria,43BK2@68525|delta/epsilon subdivisions,2X6XX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Sigma-54 factor interaction domain-containing protein	-	-	-	ko:K02481,ko:K07712,ko:K07713	ko02020,map02020	M00497,M00499	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,PAS_4,Response_reg,Sigma54_activat
k59_16844_1	335543.Sfum_0824	2.21e-73	246.0	COG0493@1|root,COG1148@1|root,COG0493@2|Bacteria,COG1148@2|Bacteria,1MU2H@1224|Proteobacteria,42M6X@68525|delta/epsilon subdivisions,2X6YD@28221|Deltaproteobacteria,2MQTQ@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.17.1.10,1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388,ko:K15022	ko00680,ko00720,ko01100,ko01120,ko01200,map00680,map00720,map01100,map01120,map01200	M00356,M00357,M00377,M00563,M00567	R00134,R04540,R11928,R11931,R11943,R11944	RC00011,RC02796	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_20,Pyr_redox_2
k59_229268_1	335543.Sfum_0122	6.3e-76	253.0	COG0060@1|root,COG0060@2|Bacteria,1MVBQ@1224|Proteobacteria,42MKB@68525|delta/epsilon subdivisions,2WJ4W@28221|Deltaproteobacteria,2MQ7V@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1,zf-FPG_IleRS
k59_176218_1	1265505.ATUG01000001_gene4387	2.46e-59	189.0	COG5423@1|root,COG5423@2|Bacteria,1NWG4@1224|Proteobacteria,4307C@68525|delta/epsilon subdivisions,2WVDB@28221|Deltaproteobacteria,2MNHA@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Predicted metal-binding protein (DUF2284)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2284
k59_229269_1	370438.PTH_0459	3.36e-61	198.0	COG0559@1|root,COG0559@2|Bacteria,1V5DJ@1239|Firmicutes,24IN9@186801|Clostridia,2600T@186807|Peptococcaceae	186801|Clostridia	U	PFAM Branched-chain amino acid transport system permease component	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
k59_62607_1	1237149.C900_00604	9.61e-39	149.0	COG0834@1|root,COG2202@1|root,COG4585@1|root,COG0834@2|Bacteria,COG2202@2|Bacteria,COG4585@2|Bacteria,4NMRZ@976|Bacteroidetes,47QIU@768503|Cytophagia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISMED2,7TMR-DISM_7TM,HATPase_c,HisKA_3
k59_161208_1	1121403.AUCV01000029_gene2659	1.82e-47	171.0	COG1075@1|root,COG1075@2|Bacteria,1R5PF@1224|Proteobacteria,43BHB@68525|delta/epsilon subdivisions,2X6VQ@28221|Deltaproteobacteria,2MMMX@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Alpha/beta hydrolase of unknown function (DUF915)	-	-	-	-	-	-	-	-	-	-	-	-	DUF915
k59_168508_1	1168289.AJKI01000055_gene3693	1.89e-42	153.0	COG4974@1|root,COG4974@2|Bacteria,4NEK2@976|Bacteroidetes,2FMJC@200643|Bacteroidia,3XJ8A@558415|Marinilabiliaceae	976|Bacteroidetes	L	IS66 family element, transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS66,DDE_Tnp_IS66_C,LZ_Tnp_IS66
k59_168508_2	886379.AEWI01000170_gene1006	5.6e-40	135.0	COG3436@1|root,COG3436@2|Bacteria,4NV0F@976|Bacteroidetes,2FU7G@200643|Bacteroidia,3XK5I@558415|Marinilabiliaceae	976|Bacteroidetes	L	IS66 Orf2 like protein	-	-	-	ko:K07484	-	-	-	-	ko00000	-	-	-	TnpB_IS66
k59_168508_3	927658.AJUM01000034_gene386	3.63e-22	90.9	2AW0R@1|root,31MVB@2|Bacteria,4PJDA@976|Bacteroidetes,2G295@200643|Bacteroidia,3XKEE@558415|Marinilabiliaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Tnp_1
k59_62613_1	981384.AEYW01000004_gene1771	2.65e-38	143.0	COG1228@1|root,COG1228@2|Bacteria,1MVAF@1224|Proteobacteria,2TTYC@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	COG1228 Imidazolonepropionase and related amidohydrolases	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
k59_77840_1	580327.Tthe_0921	1.31e-13	70.9	COG1078@1|root,COG1078@2|Bacteria,1TPVB@1239|Firmicutes,24DGJ@186801|Clostridia,42FPH@68295|Thermoanaerobacterales	186801|Clostridia	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	ko:K06885	-	-	-	-	ko00000	-	-	-	HD
k59_77840_2	523845.AQXV01000049_gene949	2.4e-15	74.7	COG0125@1|root,arCOG01891@2157|Archaea,2XTAM@28890|Euryarchaeota,23QXM@183939|Methanococci	183939|Methanococci	F	PFAM thymidylate kinase	tmk	GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylate_kin
k59_115380_1	1123399.AQVE01000001_gene575	2.36e-09	57.0	COG0586@1|root,COG0586@2|Bacteria,1MX4M@1224|Proteobacteria,1RPB1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	Pfam SNARE associated Golgi protein	VV0785	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
k59_115380_2	944480.ATUV01000001_gene800	4.3e-13	74.3	COG0038@1|root,COG0038@2|Bacteria,1MV4K@1224|Proteobacteria,42N93@68525|delta/epsilon subdivisions,2WJ9N@28221|Deltaproteobacteria,2M7KB@213113|Desulfurellales	28221|Deltaproteobacteria	P	Voltage gated chloride channel	-	-	-	-	-	-	-	-	-	-	-	-	Voltage_CLC
k59_1758_1	289376.THEYE_A0111	4.35e-94	286.0	COG0499@1|root,COG0499@2|Bacteria,3J0AH@40117|Nitrospirae	40117|Nitrospirae	H	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine	ahcY	-	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
k59_62630_1	948106.AWZT01000014_gene625	1.62e-52	187.0	COG0178@1|root,COG0178@2|Bacteria,1MW0W@1224|Proteobacteria,2VI87@28216|Betaproteobacteria,1K1YU@119060|Burkholderiaceae	28216|Betaproteobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA2	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
k59_47428_1	1121396.KB892900_gene2107	1.87e-23	102.0	COG0727@1|root,COG0727@2|Bacteria,1N683@1224|Proteobacteria,42TJ1@68525|delta/epsilon subdivisions,2WQ91@28221|Deltaproteobacteria,2MKF6@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Putative zinc- or iron-chelating domain	-	-	-	-	-	-	-	-	-	-	-	-	CxxCxxCC
k59_85135_1	936596.HMPREF1495_2137	1.68e-25	108.0	COG1975@1|root,COG1975@2|Bacteria,1UZDB@1239|Firmicutes,25D6N@186801|Clostridia,1HUWN@1164882|Lachnoanaerobaculum	186801|Clostridia	O	XdhC and CoxI family	-	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	XdhC_C,XdhC_CoxI
k59_70067_1	351160.RCIX1841	5.39e-61	205.0	COG0129@1|root,arCOG04045@2157|Archaea,2XSW2@28890|Euryarchaeota,2N992@224756|Methanomicrobia	224756|Methanomicrobia	E	Belongs to the IlvD Edd family	ilvD	-	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	iAF692.Mbar_A2069	ILVD_EDD
k59_199020_1	484018.BACPLE_00794	4.22e-71	224.0	COG2304@1|root,COG2304@2|Bacteria,4NDUC@976|Bacteroidetes,2FNXM@200643|Bacteroidia,4AMB6@815|Bacteroidaceae	976|Bacteroidetes	S	Von Willebrand factor type A domain	batA	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	BatA,VWA
k59_107962_1	1125863.JAFN01000001_gene224	6.99e-32	128.0	COG0243@1|root,COG0243@2|Bacteria,1NR6J@1224|Proteobacteria,43BMM@68525|delta/epsilon subdivisions,2WJJV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
k59_100520_1	1121405.dsmv_1764	6.97e-66	219.0	COG1080@1|root,COG1080@2|Bacteria,1MUT8@1224|Proteobacteria,42P77@68525|delta/epsilon subdivisions,2WK7E@28221|Deltaproteobacteria,2MIQB@213118|Desulfobacterales	28221|Deltaproteobacteria	G	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)	ptsI	-	2.7.3.9	ko:K08483	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	8.A.7	-	-	PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C
k59_214057_1	1121405.dsmv_2787	7.82e-106	323.0	COG1154@1|root,COG1154@2|Bacteria,1MUSJ@1224|Proteobacteria,42M35@68525|delta/epsilon subdivisions,2WIX5@28221|Deltaproteobacteria,2MI30@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)	dxs	-	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	-	DXP_synthase_N,Transket_pyr,Transketolase_C
k59_229285_1	156889.Mmc1_0484	1.24e-70	229.0	COG2821@1|root,COG2821@2|Bacteria,1MXD4@1224|Proteobacteria,2TS5S@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	membrane-bound lytic murein transglycosylase	mltA	-	-	ko:K08304	-	-	-	-	ko00000,ko01000,ko01011	-	GH102	-	3D,MltA
k59_176244_1	335543.Sfum_2600	7.74e-67	216.0	COG3547@1|root,COG3547@2|Bacteria,1NGR7@1224|Proteobacteria,42NNQ@68525|delta/epsilon subdivisions,2WM2H@28221|Deltaproteobacteria,2MSJJ@213462|Syntrophobacterales	28221|Deltaproteobacteria	L	PFAM transposase IS116 IS110 IS902 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_92754_2	1454004.AW11_00535	5.99e-38	140.0	COG2267@1|root,COG2267@2|Bacteria,1QTZP@1224|Proteobacteria,2VKTF@28216|Betaproteobacteria	28216|Betaproteobacteria	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6,Hydrolase_4
k59_1771_1	1304875.JAFZ01000004_gene476	1.49e-08	53.9	2DD8T@1|root,2ZH33@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1771_2	6334.EFV57401	0.000199	48.9	KOG3629@1|root,KOG2378@2759|Eukaryota,39DVR@33154|Opisthokonta,3BBRB@33208|Metazoa,3CTHF@33213|Bilateria,40BQA@6231|Nematoda	33208|Metazoa	T	Cyclic nucleotide-monophosphate binding domain	-	GO:0008150,GO:0009966,GO:0010646,GO:0023051,GO:0032487,GO:0046578,GO:0048583,GO:0050789,GO:0050794,GO:0051056,GO:0065007,GO:1902531	-	ko:K04351	ko04015,ko04024,ko04072,ko04261,ko04670,ko04911,map04015,map04024,map04072,map04261,map04670,map04911	-	-	-	ko00000,ko00001,ko04131	-	-	-	DEP,RasGEF,RasGEF_N,cNMP_binding
k59_9537_2	335543.Sfum_2070	5.36e-26	102.0	COG1137@1|root,COG1137@2|Bacteria,1MU8M@1224|Proteobacteria,42M4J@68525|delta/epsilon subdivisions,2WJM8@28221|Deltaproteobacteria,2MQ7U@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	PFAM ABC transporter	lptB	-	-	ko:K06861	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	1.B.42.1	-	-	ABC_tran,BCA_ABC_TP_C
k59_55051_1	335543.Sfum_0452	5.77e-56	185.0	COG2890@1|root,COG2890@2|Bacteria,1N5B4@1224|Proteobacteria,42VIS@68525|delta/epsilon subdivisions,2WR53@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	PFAM methyltransferase small	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_16
k59_16885_1	96561.Dole_0042	1.25e-66	212.0	COG0414@1|root,COG0414@2|Bacteria,1MV1S@1224|Proteobacteria,42N3J@68525|delta/epsilon subdivisions,2WJ19@28221|Deltaproteobacteria,2MHRN@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate	panC	GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605	6.3.2.1	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R02473	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_ligase
k59_123257_1	314265.R2601_06308	3.12e-89	276.0	COG3547@1|root,COG3547@2|Bacteria,1Q4TE@1224|Proteobacteria,2TT7C@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_92766_1	398767.Glov_3274	0.00035	43.9	COG1344@1|root,COG1344@2|Bacteria	2|Bacteria	N	bacterial-type flagellum-dependent cell motility	flgL	-	-	ko:K02397	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flagellin_C,Flagellin_N
k59_214076_1	641491.DND132_0702	0.000796	42.4	COG1977@1|root,COG1977@2|Bacteria,1NH6M@1224|Proteobacteria,42X05@68525|delta/epsilon subdivisions,2WSK5@28221|Deltaproteobacteria,2MD55@213115|Desulfovibrionales	28221|Deltaproteobacteria	H	PFAM ThiamineS	-	-	-	-	-	-	-	-	-	-	-	-	ThiS,Ub-Mut7C
k59_138995_1	269799.Gmet_1934	2.13e-85	272.0	COG1154@1|root,COG1154@2|Bacteria,1MUSJ@1224|Proteobacteria,42M35@68525|delta/epsilon subdivisions,2WIX5@28221|Deltaproteobacteria,43UFS@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)	dxs	-	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	-	DXP_synthase_N,Transket_pyr,Transketolase_C
k59_115855_1	1353531.AZNX01000001_gene1673	2.15e-39	149.0	COG1009@1|root,COG2111@1|root,COG1009@2|Bacteria,COG2111@2|Bacteria,1MW2M@1224|Proteobacteria,2TRIR@28211|Alphaproteobacteria,4B8KB@82115|Rhizobiaceae	28211|Alphaproteobacteria	CP	NADH ubiquinone oxidoreductase subunit 5 (Chain L) multisubunit Na H antiporter, MnhA subunit	mrpA	GO:0003674,GO:0005215,GO:0005451,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008150,GO:0008324,GO:0015075,GO:0015077,GO:0015078,GO:0015081,GO:0015291,GO:0015297,GO:0015298,GO:0015299,GO:0015318,GO:0015385,GO:0015491,GO:0015672,GO:0022804,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0035725,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0098655,GO:0098660,GO:0098662,GO:0099516,GO:1902600	-	ko:K05565	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	DUF4040,Proton_antipo_M,Proton_antipo_N
k59_93281_1	1232437.KL661965_gene3271	3.32e-60	189.0	COG1142@1|root,COG1142@2|Bacteria,1MWE1@1224|Proteobacteria,42TQV@68525|delta/epsilon subdivisions,2WQAE@28221|Deltaproteobacteria,2MKXW@213118|Desulfobacterales	28221|Deltaproteobacteria	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_11,Fer4_4,Fer4_7
k59_176764_1	7668.SPU_028323-tr	1.2e-58	188.0	2BG5J@1|root,2S18N@2759|Eukaryota,3A435@33154|Opisthokonta,3BRGG@33208|Metazoa,3D8KM@33213|Bilateria	33208|Metazoa	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_63106_1	313628.LNTAR_16863	3.19e-54	182.0	COG3547@1|root,COG3547@2|Bacteria	2|Bacteria	L	Transposase (IS116 IS110 IS902 family)	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_139001_1	641491.DND132_3084	0.000998	41.2	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42ME4@68525|delta/epsilon subdivisions,2WJA5@28221|Deltaproteobacteria,2MA0T@213115|Desulfovibrionales	28221|Deltaproteobacteria	K	PFAM sigma-54 factor interaction domain-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
k59_63109_1	1123326.JFBL01000020_gene2641	9.49e-69	221.0	COG0160@1|root,COG0160@2|Bacteria,1QY1E@1224|Proteobacteria,43C8R@68525|delta/epsilon subdivisions	1224|Proteobacteria	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.11,2.6.1.17,2.6.1.19,2.6.1.22,2.6.1.33,2.6.1.36	ko:K00821,ko:K03918,ko:K07250,ko:K20428	ko00220,ko00250,ko00280,ko00300,ko00410,ko00525,ko00640,ko00650,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00250,map00280,map00300,map00410,map00525,map00640,map00650,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00027,M00028,M00845	R00457,R00908,R01648,R02283,R02773,R04188,R04475	RC00006,RC00062,RC00160,RC00781	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
k59_25124_2	1123355.JHYO01000019_gene1689	1.4e-39	143.0	COG0683@1|root,COG0683@2|Bacteria,1MWNB@1224|Proteobacteria,2TTAH@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component	MA20_26550	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
k59_123843_1	1121405.dsmv_0691	1.17e-111	337.0	COG5421@1|root,COG5421@2|Bacteria,1R3NX@1224|Proteobacteria,42QDV@68525|delta/epsilon subdivisions,2WIRQ@28221|Deltaproteobacteria,2MN1S@213118|Desulfobacterales	68525|delta/epsilon subdivisions	L	PFAM transposase IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
k59_40340_1	1192034.CAP_4164	2.77e-22	97.4	COG1651@1|root,COG1651@2|Bacteria	2|Bacteria	O	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_4
k59_224172_1	1230457.C476_05477	7.52e-06	52.8	arCOG07560@1|root,arCOG07560@2157|Archaea,2XTTK@28890|Euryarchaeota,23TWW@183963|Halobacteria	183963|Halobacteria	Q	Archaeal Type IV pilin, N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	CARDB
k59_178496_1	1089553.Tph_c27720	5.32e-67	214.0	arCOG06710@1|root,2ZAS5@2|Bacteria,1V0TY@1239|Firmicutes,24ZW3@186801|Clostridia	186801|Clostridia	H	Dimethylamine methyltransferase (Dimeth_PyL)	-	-	2.1.1.249	ko:K16178	ko00680,ko01120,ko01200,map00680,map01120,map01200	M00563	R09999,R10015	RC00035,RC00556,RC01144,RC02986	ko00000,ko00001,ko00002,ko01000	-	-	-	Dimeth_Pyl
k59_178496_2	1089553.Tph_c27710	2.56e-09	54.7	arCOG06710@1|root,2ZUSJ@2|Bacteria	2|Bacteria	H	Dimethylamine methyltransferase (Dimeth_PyL)	-	-	2.1.1.249	ko:K16178	ko00680,ko01120,ko01200,map00680,map01120,map01200	M00563	R09999,R10015	RC00035,RC00556,RC01144,RC02986	ko00000,ko00001,ko00002,ko01000	-	-	-	Dimeth_Pyl
k59_239159_1	880072.Desac_0868	2.88e-58	194.0	COG0683@1|root,COG0683@2|Bacteria,1NHBN@1224|Proteobacteria,42RYV@68525|delta/epsilon subdivisions,2WNEF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	PFAM Extracellular ligand-binding receptor	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
k59_35120_1	439235.Dalk_4766	1.19e-120	350.0	COG1028@1|root,COG1028@2|Bacteria,1MU5Y@1224|Proteobacteria,42PM3@68525|delta/epsilon subdivisions,2WKSN@28221|Deltaproteobacteria,2MI0X@213118|Desulfobacterales	28221|Deltaproteobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.30	ko:K00019	ko00072,ko00650,ko01100,map00072,map00650,map01100	M00088	R01361	RC00117	ko00000,ko00001,ko00002,ko01000	-	-	-	adh_short_C2
k59_80621_1	1121434.AULY01000007_gene1492	1.06e-48	174.0	COG0038@1|root,COG0038@2|Bacteria,1MV4K@1224|Proteobacteria,42PJQ@68525|delta/epsilon subdivisions,2WKR4@28221|Deltaproteobacteria,2M7SH@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	Voltage gated chloride channel	-	-	-	ko:K03281	-	-	-	-	ko00000	2.A.49	-	iAF987.Gmet_3470	CBS,Voltage_CLC
k59_178503_1	933262.AXAM01000010_gene1349	1.15e-37	145.0	COG1196@1|root,COG1196@2|Bacteria,1MUAQ@1224|Proteobacteria,42MN9@68525|delta/epsilon subdivisions,2WJZF@28221|Deltaproteobacteria,2MHU0@213118|Desulfobacterales	28221|Deltaproteobacteria	D	Required for chromosome condensation and partitioning	smc	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
k59_42040_1	269799.Gmet_2371	4.66e-32	134.0	COG1480@1|root,COG1480@2|Bacteria,1NCY5@1224|Proteobacteria,42MI9@68525|delta/epsilon subdivisions,2WJI1@28221|Deltaproteobacteria,43UC4@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Metal-dependent phosphohydrolase	-	-	-	ko:K07037	-	-	-	-	ko00000	-	-	-	7TM-7TMR_HD,7TMR-HDED,HD
k59_95701_1	1304885.AUEY01000040_gene1598	6.34e-82	249.0	COG0569@1|root,COG0569@2|Bacteria,1R7KM@1224|Proteobacteria,42PJH@68525|delta/epsilon subdivisions,2WMZT@28221|Deltaproteobacteria,2MJ9H@213118|Desulfobacterales	28221|Deltaproteobacteria	P	PFAM TrkA-N domain	-	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
k59_80624_1	439235.Dalk_5190	6.5e-55	188.0	COG3547@1|root,COG3547@2|Bacteria,1NCHY@1224|Proteobacteria,42TM4@68525|delta/epsilon subdivisions,2WR4U@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	PFAM transposase IS116 IS110 IS902 family	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_216718_1	1298867.AUES01000066_gene4685	3.8e-33	131.0	COG1572@1|root,COG1572@2|Bacteria,1QVRG@1224|Proteobacteria	1224|Proteobacteria	G	PFAM SMP-30 Gluconolaconase	-	-	-	ko:K20952	ko05111,map05111	-	-	-	ko00000,ko00001	-	-	-	Beta-prism_lec,Calx-beta,DUF5122
k59_239168_2	1117319.PSPO_09964	2.59e-70	239.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,2Q1ZW@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K18138	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
k59_171422_2	1232437.KL662010_gene1571	5.28e-92	275.0	COG2357@1|root,COG2357@2|Bacteria,1RCHE@1224|Proteobacteria,42PPK@68525|delta/epsilon subdivisions,2WJBS@28221|Deltaproteobacteria,2MHSG@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Region found in RelA / SpoT proteins	-	-	-	-	-	-	-	-	-	-	-	-	RelA_SpoT
k59_193677_1	913865.DOT_3301	8.91e-21	94.7	COG0517@1|root,COG0517@2|Bacteria,1TQ4J@1239|Firmicutes,24B68@186801|Clostridia,260BK@186807|Peptococcaceae	186801|Clostridia	S	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	Y2_Tnp,Zn_Tnp_IS91
k59_148136_1	96561.Dole_2836	2.33e-66	219.0	COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,42M01@68525|delta/epsilon subdivisions,2WJ7M@28221|Deltaproteobacteria,2MHMW@213118|Desulfobacterales	28221|Deltaproteobacteria	V	Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation	msbA	-	-	ko:K06147,ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
k59_156484_2	443254.Marpi_0837	1.09e-43	160.0	COG0366@1|root,COG0366@2|Bacteria	2|Bacteria	G	hydrolase activity, hydrolyzing O-glycosyl compounds	amyA	-	2.4.1.7	ko:K00690	ko00500,map00500	-	R00803	RC00028	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,DUF3459,Malt_amylase_C
k59_201863_2	446469.Sked_19050	1.67e-18	90.9	COG1215@1|root,COG1215@2|Bacteria,2GJCE@201174|Actinobacteria	201174|Actinobacteria	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Polysacc_deac_1
k59_49855_1	1265505.ATUG01000001_gene4305	2.15e-40	144.0	COG2423@1|root,COG2423@2|Bacteria	2|Bacteria	E	ornithine cyclodeaminase activity	ocd	-	1.5.1.51,2.5.1.140,4.3.1.12	ko:K01750,ko:K16182,ko:K21721,ko:K21949	ko00300,ko00330,ko01110,ko01120,ko01130,ko01230,map00300,map00330,map01110,map01120,map01130,map01230	-	R00671,R10012,R11705	RC00062,RC00354	ko00000,ko00001,ko01000	-	-	iSB619.SA_RS00720	OCD_Mu_crystall
k59_193678_2	1235792.C808_05390	1.41e-48	174.0	28HHC@1|root,2Z7T2@2|Bacteria,1TR3B@1239|Firmicutes,24D5P@186801|Clostridia,27KWD@186928|unclassified Lachnospiraceae	186801|Clostridia	S	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_24
k59_117872_1	177437.HRM2_15130	3.06e-60	200.0	COG5557@1|root,COG5557@2|Bacteria,1QURB@1224|Proteobacteria,43BT1@68525|delta/epsilon subdivisions,2X73S@28221|Deltaproteobacteria,2MMX3@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Pfam Polysulphide reductase, NrfD	actF	-	-	-	-	-	-	-	-	-	-	-	-
k59_110879_1	1304885.AUEY01000017_gene3765	2.67e-103	310.0	COG0330@1|root,COG0330@2|Bacteria,1R8RD@1224|Proteobacteria,42QFB@68525|delta/epsilon subdivisions,2WJQE@28221|Deltaproteobacteria,2MMN0@213118|Desulfobacterales	28221|Deltaproteobacteria	O	prohibitin homologues	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
k59_49857_1	1499967.BAYZ01000131_gene329	9.3e-108	330.0	COG2987@1|root,COG2987@2|Bacteria,2NP09@2323|unclassified Bacteria	2|Bacteria	E	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate	hutU	GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006547,GO:0006548,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009987,GO:0016054,GO:0016153,GO:0016829,GO:0016835,GO:0016836,GO:0019439,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046395,GO:0046483,GO:0046700,GO:0052803,GO:0052805,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	4.2.1.49	ko:K01712	ko00340,ko01100,map00340,map01100	M00045	R02914	RC00804	ko00000,ko00001,ko00002,ko01000	-	-	iECIAI39_1322.ECIAI39_0688	Urocanase,Urocanase_C,Urocanase_N
k59_3843_1	1191523.MROS_1011	6.14e-100	308.0	COG3547@1|root,COG3547@2|Bacteria	2|Bacteria	L	Transposase (IS116 IS110 IS902 family)	-	-	-	ko:K07486	-	-	-	-	ko00000	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_232444_1	706587.Desti_5299	3.62e-58	200.0	COG0188@1|root,COG0188@2|Bacteria,1MUGG@1224|Proteobacteria,42KZ9@68525|delta/epsilon subdivisions,2WJBC@28221|Deltaproteobacteria,2MR01@213462|Syntrophobacterales	2|Bacteria	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	parC	GO:0000819,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006265,GO:0006276,GO:0006725,GO:0006807,GO:0006996,GO:0007049,GO:0007059,GO:0007062,GO:0008150,GO:0008152,GO:0009330,GO:0009987,GO:0016020,GO:0016043,GO:0019897,GO:0019898,GO:0022402,GO:0030541,GO:0032991,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0098813,GO:1901360,GO:1901363	5.99.1.3	ko:K02469,ko:K02621	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
k59_126195_1	1121943.KB900008_gene1991	9.91e-49	179.0	COG1196@1|root,COG5283@1|root,COG1196@2|Bacteria,COG5283@2|Bacteria,1R97W@1224|Proteobacteria	1224|Proteobacteria	D	Phage-related minor tail protein	-	-	-	-	-	-	-	-	-	-	-	-	PhageMin_Tail
k59_201878_1	670487.Ocepr_0084	1.26e-43	158.0	COG0554@1|root,COG0554@2|Bacteria,1WI6Q@1297|Deinococcus-Thermus	2|Bacteria	C	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate	-	-	2.7.1.30	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	-	R00847	RC00002,RC00017	ko00000,ko00001,ko01000,ko04147	-	-	-	FGGY_C,FGGY_N
k59_232456_2	177437.HRM2_03680	0.000232	42.0	294U0@1|root,2ZS77@2|Bacteria,1PBP0@1224|Proteobacteria,4329Q@68525|delta/epsilon subdivisions,2WY84@28221|Deltaproteobacteria,2MP66@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_156505_1	269799.Gmet_2452	6.77e-47	158.0	COG0526@1|root,COG0526@2|Bacteria,1N726@1224|Proteobacteria,42U61@68525|delta/epsilon subdivisions,2WQRF@28221|Deltaproteobacteria,43UYU@69541|Desulfuromonadales	28221|Deltaproteobacteria	CO	Thioredoxin-like	resA	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
k59_126205_1	933262.AXAM01000088_gene298	1.04e-92	283.0	COG2605@1|root,COG2605@2|Bacteria,1QW1A@1224|Proteobacteria,42N0X@68525|delta/epsilon subdivisions,2WJYP@28221|Deltaproteobacteria,2MHZ0@213118|Desulfobacterales	28221|Deltaproteobacteria	S	PFAM GHMP kinase	-	-	2.7.1.168	ko:K07031	ko00540,map00540	-	R09770	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
k59_87838_1	177437.HRM2_27650	6.75e-48	177.0	COG3419@1|root,COG3419@2|Bacteria,1NUAV@1224|Proteobacteria,42NJ7@68525|delta/epsilon subdivisions,2WKJV@28221|Deltaproteobacteria,2MPX6@213118|Desulfobacterales	28221|Deltaproteobacteria	NU	Tfp pilus assembly protein tip-associated adhesin	pilY1	-	-	ko:K02674	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	Neisseria_PilC,PA14
k59_224202_1	335543.Sfum_1681	6.24e-70	224.0	COG0683@1|root,COG0683@2|Bacteria,1MXR4@1224|Proteobacteria,42MXX@68525|delta/epsilon subdivisions,2WKJM@28221|Deltaproteobacteria,2MQZG@213462|Syntrophobacterales	28221|Deltaproteobacteria	E	PFAM Extracellular ligand-binding receptor	livK-1	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	iAF987.Gmet_1823	Peripla_BP_6
k59_72996_1	1094980.Mpsy_1741	1.97e-24	102.0	COG1045@1|root,arCOG01847@2157|Archaea,2XUZJ@28890|Euryarchaeota,2N9VY@224756|Methanomicrobia	224756|Methanomicrobia	E	TIGRFAM serine O-acetyltransferase	-	-	2.3.1.30	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	M00021	R00586	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	FeS_assembly_P,Hexapep,SATase_N
k59_117880_1	983545.Glaag_2332	1.28e-49	183.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,464D1@72275|Alteromonadaceae	1236|Gammaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K18138	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
k59_209596_1	96561.Dole_1616	6.01e-32	120.0	COG5401@1|root,COG5401@2|Bacteria,1NA0G@1224|Proteobacteria,42V1V@68525|delta/epsilon subdivisions,2WRCV@28221|Deltaproteobacteria,2MKUK@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Sporulation and spore germination	-	-	-	-	-	-	-	-	-	-	-	-	Germane
k59_4371_1	760568.Desku_2029	2.02e-47	165.0	COG0482@1|root,COG0482@2|Bacteria,1TPIZ@1239|Firmicutes,247YV@186801|Clostridia,2608Q@186807|Peptococcaceae	186801|Clostridia	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
k59_96271_1	84531.JMTZ01000051_gene912	2.31e-15	78.2	COG1878@1|root,COG1878@2|Bacteria,1R8IH@1224|Proteobacteria,1S46Y@1236|Gammaproteobacteria,1X5VG@135614|Xanthomonadales	135614|Xanthomonadales	S	Putative cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Cyclase
k59_239831_1	439235.Dalk_3112	2.59e-40	145.0	COG2203@1|root,COG3437@1|root,COG2203@2|Bacteria,COG3437@2|Bacteria,1RGKE@1224|Proteobacteria,42QI9@68525|delta/epsilon subdivisions,2WIV3@28221|Deltaproteobacteria,2MI92@213118|Desulfobacterales	28221|Deltaproteobacteria	T	GAF domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HD,Lactamase_B_2
k59_187653_1	706587.Desti_5326	6.22e-30	119.0	COG3852@1|root,COG3852@2|Bacteria,1R1JU@1224|Proteobacteria,43DA4@68525|delta/epsilon subdivisions,2X8GR@28221|Deltaproteobacteria	2|Bacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	regM	-	2.7.13.3	ko:K02668,ko:K07709	ko02020,map02020	M00499,M00501	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	HATPase_c,HisKA,PAS,PAS_9,Response_reg
k59_20118_1	879212.DespoDRAFT_01472	2.56e-19	84.7	COG3677@1|root,COG3677@2|Bacteria	2|Bacteria	L	transposition, DNA-mediated	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS1595,HTH_23
k59_134406_1	7668.SPU_001651-tr	2.48e-56	198.0	COG2801@1|root,KOG0017@2759|Eukaryota,38F42@33154|Opisthokonta,3BA5H@33208|Metazoa	33208|Metazoa	OU	K02A2.6-like	-	-	-	-	-	-	-	-	-	-	-	-	RVT_1,SCAN,gag-asp_proteas,rve,zf-CCHC,zf-H2C2
k59_224742_1	1121405.dsmv_2738	2.03e-72	238.0	COG1185@1|root,COG1185@2|Bacteria,1MVB9@1224|Proteobacteria,42MTZ@68525|delta/epsilon subdivisions,2WJCE@28221|Deltaproteobacteria,2MIS9@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004654,GO:0005488,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
k59_224742_2	243231.GSU1594	7.49e-25	102.0	COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,42P7N@68525|delta/epsilon subdivisions,2WJKE@28221|Deltaproteobacteria,43TZJ@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	PFAM peptidase M16 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
k59_103974_1	1121403.AUCV01000045_gene1130	4.03e-79	265.0	COG0642@1|root,COG2204@1|root,COG2204@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,43CHE@68525|delta/epsilon subdivisions,2X7SI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
k59_239842_1	439235.Dalk_2556	2.35e-76	236.0	COG0685@1|root,COG0685@2|Bacteria,1MWQ3@1224|Proteobacteria,42PKP@68525|delta/epsilon subdivisions,2WK0A@28221|Deltaproteobacteria,2MIZB@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Methylenetetrahydrofolate reductase	-	-	-	-	-	-	-	-	-	-	-	-	MTHFR
k59_210195_1	1304888.ATWF01000001_gene1077	5.51e-52	172.0	COG0559@1|root,COG0559@2|Bacteria,2GEK5@200930|Deferribacteres	200930|Deferribacteres	P	Branched-chain amino acid transport system / permease component	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
k59_35834_1	1265505.ATUG01000003_gene519	1.45e-16	85.5	COG3829@1|root,COG4191@1|root,COG3829@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42NFY@68525|delta/epsilon subdivisions,2WKC0@28221|Deltaproteobacteria,2MN70@213118|Desulfobacterales	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_9
k59_217377_1	335543.Sfum_0824	7.56e-90	291.0	COG0493@1|root,COG1148@1|root,COG0493@2|Bacteria,COG1148@2|Bacteria,1MU2H@1224|Proteobacteria,42M6X@68525|delta/epsilon subdivisions,2X6YD@28221|Deltaproteobacteria,2MQTQ@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.17.1.10,1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388,ko:K15022	ko00680,ko00720,ko01100,ko01120,ko01200,map00680,map00720,map01100,map01120,map01200	M00356,M00357,M00377,M00563,M00567	R00134,R04540,R11928,R11931,R11943,R11944	RC00011,RC02796	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_20,Pyr_redox_2
k59_13194_1	1294143.H681_14790	4.45e-55	187.0	COG2067@1|root,COG2067@2|Bacteria,1R3SS@1224|Proteobacteria,1S0X2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	long-chain fatty acid transport protein	-	-	-	ko:K06076	-	-	-	-	ko00000,ko02000	1.B.9	-	-	Toluene_X
k59_141953_1	526222.Desal_1719	1.59e-34	124.0	COG1126@1|root,COG1126@2|Bacteria,1MU9Q@1224|Proteobacteria,42M0S@68525|delta/epsilon subdivisions,2WITR@28221|Deltaproteobacteria,2M7ZW@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	PFAM ABC transporter related	-	-	3.6.3.21	ko:K02028,ko:K09972,ko:K10038	ko02010,map02010	M00227,M00232,M00236	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.3,3.A.1.3.17,3.A.1.3.18,3.A.1.3.2,3.A.1.3.7,3.A.1.3.8	-	-	ABC_tran
k59_141953_2	883.DvMF_1343	6.03e-64	204.0	COG0765@1|root,COG0765@2|Bacteria,1MX3E@1224|Proteobacteria,42N9B@68525|delta/epsilon subdivisions,2WIYW@28221|Deltaproteobacteria,2M9VH@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	TIGRFAM polar amino acid ABC transporter, inner membrane subunit	-	-	-	ko:K02029,ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	BPD_transp_1,SBP_bac_3
k59_88554_1	1379270.AUXF01000004_gene3069	1.51e-24	107.0	28M0D@1|root,2ZAFE@2|Bacteria,1ZUP5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Putative ATP-binding cassette	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran_2
k59_81235_1	1265505.ATUG01000002_gene1866	2.76e-08	53.5	COG0035@1|root,COG0035@2|Bacteria,1MV4N@1224|Proteobacteria,42NNR@68525|delta/epsilon subdivisions,2WK6M@28221|Deltaproteobacteria,2MJ9Q@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate	upp	GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.4.2.9	ko:K00761	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000	-	-	-	UPRTase
k59_50320_1	877455.Metbo_2269	4.96e-42	146.0	COG1646@1|root,arCOG01085@2157|Archaea,2XTEC@28890|Euryarchaeota,23NWS@183925|Methanobacteria	183925|Methanobacteria	H	Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids	-	-	2.5.1.41	ko:K17104	ko00564,map00564	-	R04158	RC01091	ko00000,ko00001,ko01000	-	-	-	PcrB
k59_13195_1	1232437.KL662020_gene705	4.17e-69	223.0	COG3547@1|root,COG3547@2|Bacteria	2|Bacteria	L	Transposase (IS116 IS110 IS902 family)	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_118462_1	264198.Reut_C6194	6.36e-108	330.0	COG0465@1|root,COG0465@2|Bacteria,1MU6J@1224|Proteobacteria,2VHEM@28216|Betaproteobacteria,1K0XH@119060|Burkholderiaceae	28216|Betaproteobacteria	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	-	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
k59_224755_2	398767.Glov_0511	1.21e-20	94.4	COG1906@1|root,COG1906@2|Bacteria,1RAQQ@1224|Proteobacteria,42QZ0@68525|delta/epsilon subdivisions,2WMXK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Protein of unknown function (DUF401)	-	-	-	ko:K09133	-	-	-	-	ko00000	-	-	-	DUF401
k59_217382_1	335543.Sfum_0615	5.72e-74	243.0	COG0303@1|root,COG1910@1|root,COG0303@2|Bacteria,COG1910@2|Bacteria,1MVD5@1224|Proteobacteria,42NQY@68525|delta/epsilon subdivisions,2WISG@28221|Deltaproteobacteria,2MQ4V@213462|Syntrophobacterales	28221|Deltaproteobacteria	HP	TIGRFAM molybdenum cofactor synthesis domain	-	-	2.10.1.1	ko:K03750,ko:K07219	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N,PBP_like
k59_164156_1	335543.Sfum_2958	1.06e-83	260.0	COG0205@1|root,COG0205@2|Bacteria,1MVN3@1224|Proteobacteria,42NMZ@68525|delta/epsilon subdivisions,2WIZ0@28221|Deltaproteobacteria,2MRBW@213462|Syntrophobacterales	28221|Deltaproteobacteria	F	Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Atypical ATP- dependent clade X sub-subfamily	pfkA	-	2.7.1.11	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	M00001,M00345	R00756,R03236,R03237,R03238,R03239,R04779	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	-	-	-	PFK
k59_111448_2	626887.J057_13241	1.98e-37	129.0	COG2329@1|root,COG2329@2|Bacteria,1N2ZS@1224|Proteobacteria	1224|Proteobacteria	S	Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_179157_1	1410632.JHWW01000011_gene2436	1.47e-32	121.0	COG0742@1|root,COG0742@2|Bacteria,1V3JF@1239|Firmicutes,24JHR@186801|Clostridia,27MPE@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Conserved hypothetical protein 95	rsmD	-	2.1.1.171	ko:K08316	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Cons_hypoth95
k59_172123_1	444860.E3SIW4_9CAUD	2.52e-69	220.0	4QFU0@10239|Viruses,4QW3E@35237|dsDNA viruses  no RNA stage,4QUG7@28883|Caudovirales,4QI5N@10662|Myoviridae	10662|Myoviridae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_233115_1	1121918.ARWE01000001_gene2276	1.44e-86	285.0	COG0086@1|root,COG0086@2|Bacteria,1MU3M@1224|Proteobacteria,42NAW@68525|delta/epsilon subdivisions,2WISU@28221|Deltaproteobacteria,43S5H@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	RNA polymerase I subunit A N-terminus	rpoC	-	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
k59_187662_1	96561.Dole_0171	1.25e-83	267.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,42MMK@68525|delta/epsilon subdivisions,2WJC1@28221|Deltaproteobacteria,2MIZF@213118|Desulfobacterales	28221|Deltaproteobacteria	S	PFAM ABC transporter	uup	-	-	ko:K15738	-	-	-	-	ko00000,ko02000	3.A.1.120.6	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
k59_148693_1	56107.Cylst_6262	3.99e-35	128.0	COG0667@1|root,COG0667@2|Bacteria,1G3GW@1117|Cyanobacteria,1HMUJ@1161|Nostocales	1117|Cyanobacteria	C	PFAM aldo keto reductase	-	-	1.1.1.65	ko:K05275	ko00750,ko01100,ko01120,map00750,map01100,map01120	-	R01708	RC00116	ko00000,ko00001,ko01000	-	-	-	Aldo_ket_red
k59_172126_1	177437.HRM2_20930	5.7e-91	276.0	COG2358@1|root,COG2358@2|Bacteria,1MXW1@1224|Proteobacteria,42MR6@68525|delta/epsilon subdivisions,2WITP@28221|Deltaproteobacteria,2MHTE@213118|Desulfobacterales	28221|Deltaproteobacteria	S	TIGRFAM TRAP transporter solute receptor, TAXI family	-	-	-	ko:K07080	-	-	-	-	ko00000	-	-	-	NMT1_3
k59_202549_1	1167006.UWK_00558	1.54e-67	215.0	COG2864@1|root,COG2864@2|Bacteria,1PAKU@1224|Proteobacteria	1224|Proteobacteria	C	formate dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_20156_1	933262.AXAM01000034_gene1574	2.62e-48	159.0	COG2109@1|root,COG2109@2|Bacteria,1MUN6@1224|Proteobacteria,42RPD@68525|delta/epsilon subdivisions,2WNI0@28221|Deltaproteobacteria,2MK1B@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids	-	-	2.5.1.17	ko:K19221	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	CobA_CobO_BtuR
k59_157025_1	153948.NAL212_3119	3.99e-85	261.0	COG3677@1|root,COG3677@2|Bacteria,1R3ZS@1224|Proteobacteria,2WFCR@28216|Betaproteobacteria	1224|Proteobacteria	L	Transposase zinc-ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS1595,Zn_Tnp_IS1595
k59_111455_1	1121405.dsmv_1335	3.8e-125	370.0	COG1139@1|root,COG1139@2|Bacteria,1MV6J@1224|Proteobacteria,42MN2@68525|delta/epsilon subdivisions,2WIMJ@28221|Deltaproteobacteria,2MHYD@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Domain of unknown function (DUF3390)	-	-	-	ko:K18929	-	-	-	-	ko00000	-	-	-	DUF3390,Fer4_8,LUD_dom
k59_55856_1	1047013.AQSP01000138_gene1042	4.34e-10	60.1	COG1089@1|root,COG1089@2|Bacteria,2NP6U@2323|unclassified Bacteria	2|Bacteria	M	Polysaccharide biosynthesis protein	wcbK	-	1.1.1.281,4.2.1.47	ko:K01711,ko:K15856	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R00888,R03397,R03399	RC00182,RC00402	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
k59_192122_1	1379698.RBG1_1C00001G0023	9.43e-15	71.6	COG0852@1|root,COG0852@2|Bacteria	2|Bacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	-	-	-	-	-	-	-	-	-	-	-	Complex1_30kDa
k59_192122_2	335543.Sfum_0202	3.54e-40	142.0	COG0649@1|root,COG0649@2|Bacteria,1MVIN@1224|Proteobacteria,42M9G@68525|delta/epsilon subdivisions,2WIS7@28221|Deltaproteobacteria,2MQ5T@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0016020,GO:0044424,GO:0044464,GO:0071944	1.6.5.3	ko:K00333,ko:K13378,ko:K13380	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa,Complex1_49kDa
k59_184770_1	1121405.dsmv_1717	1.25e-69	221.0	COG0618@1|root,COG0618@2|Bacteria,1N0JS@1224|Proteobacteria,42P1S@68525|delta/epsilon subdivisions,2WJV0@28221|Deltaproteobacteria,2MI7M@213118|Desulfobacterales	28221|Deltaproteobacteria	S	PFAM phosphoesterase RecJ domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DHH,DHHA1
k59_32907_1	1121405.dsmv_1078	9e-40	155.0	COG0243@1|root,COG0243@2|Bacteria,1R4RR@1224|Proteobacteria,42PA5@68525|delta/epsilon subdivisions,2WM0K@28221|Deltaproteobacteria,2MI3Z@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	qrcB	-	-	ko:K08357	ko00920,ko01120,ko02020,map00920,map01120,map02020	-	R10150	RC03109	ko00000,ko00001,ko02000	5.A.3.10	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
k59_184776_1	1037409.BJ6T_79860	1.22e-109	330.0	COG3344@1|root,COG3344@2|Bacteria,1MVI1@1224|Proteobacteria,2U0JQ@28211|Alphaproteobacteria,3JXFE@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	L	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	Intron_maturas2,RVT_1
k59_25354_1	316067.Geob_1228	1.19e-25	99.4	COG1846@1|root,COG1846@2|Bacteria,1ND45@1224|Proteobacteria,42VCT@68525|delta/epsilon subdivisions,2WSSM@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	ko:K15973	-	-	-	-	ko00000,ko03000	-	-	-	MarR
k59_32908_1	931627.MycrhDRAFT_0457	0.000544	47.8	COG0243@1|root,COG0243@2|Bacteria,2GNYQ@201174|Actinobacteria,233RN@1762|Mycobacteriaceae	201174|Actinobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	1.17.1.9	ko:K00122	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
k59_101359_1	1265505.ATUG01000002_gene1014	1.78e-26	107.0	28J96@1|root,2Z947@2|Bacteria,1R6TE@1224|Proteobacteria,42PZG@68525|delta/epsilon subdivisions,2WIKY@28221|Deltaproteobacteria,2MHY0@213118|Desulfobacterales	28221|Deltaproteobacteria	S	PFAM Oligopeptide transporter OPT superfamily	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_10331_2	1121405.dsmv_2911	4.02e-31	117.0	COG0805@1|root,COG0805@2|Bacteria,1MVAY@1224|Proteobacteria,42MM7@68525|delta/epsilon subdivisions,2WKJW@28221|Deltaproteobacteria,2MI7G@213118|Desulfobacterales	28221|Deltaproteobacteria	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides	tatC	-	-	ko:K03118	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	TatC
k59_17608_1	1499967.BAYZ01000009_gene5391	3.21e-119	365.0	COG2766@1|root,COG2766@2|Bacteria	2|Bacteria	T	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	AAA_PrkA,PrkA
k59_222654_1	504487.JCM19302_3226	1.48e-28	111.0	COG0745@1|root,COG0745@2|Bacteria,4NG7D@976|Bacteroidetes,1HWZ6@117743|Flavobacteriia	976|Bacteroidetes	T	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	phoP	-	-	ko:K07658	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
k59_78617_1	96561.Dole_1719	1.2e-65	225.0	COG1196@1|root,COG1196@2|Bacteria,1MUAQ@1224|Proteobacteria,42MN9@68525|delta/epsilon subdivisions,2WJZF@28221|Deltaproteobacteria,2MHU0@213118|Desulfobacterales	28221|Deltaproteobacteria	D	Required for chromosome condensation and partitioning	smc	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
k59_230129_1	933262.AXAM01000063_gene622	3.55e-94	293.0	COG0365@1|root,COG0365@2|Bacteria,1MUX7@1224|Proteobacteria,42P5R@68525|delta/epsilon subdivisions,2WJDU@28221|Deltaproteobacteria,2MI4P@213118|Desulfobacterales	28221|Deltaproteobacteria	I	PFAM AMP-dependent synthetase and ligase	-	-	6.2.1.16	ko:K01907	ko00280,ko00650,map00280,map00650	-	R01357	RC00004,RC00014	ko00000,ko00001,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
k59_55884_1	335543.Sfum_0540	2.64e-26	112.0	COG4796@1|root,COG4796@2|Bacteria,1QTT6@1224|Proteobacteria,42MKN@68525|delta/epsilon subdivisions,2WJV6@28221|Deltaproteobacteria,2MQHQ@213462|Syntrophobacterales	28221|Deltaproteobacteria	U	Secretin and TonB N terminus short domain	pilQ	-	-	ko:K02666	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	AMIN,STN,Secretin,Secretin_N
k59_25374_1	1121413.JMKT01000009_gene2216	5.49e-84	259.0	COG0243@1|root,COG0243@2|Bacteria,1MWPS@1224|Proteobacteria,42QIW@68525|delta/epsilon subdivisions,2WJPY@28221|Deltaproteobacteria,2MB0B@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	molybdopterin oxidoreductase Fe4S4	-	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Molybdop_Fe4S4,Molybdopterin,TAT_signal
k59_207469_1	1121422.AUMW01000016_gene2095	3.26e-45	159.0	COG5433@1|root,COG5433@2|Bacteria,1V3B8@1239|Firmicutes,25DWJ@186801|Clostridia	186801|Clostridia	L	DDE_Tnp_1-associated	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_214808_1	933262.AXAM01000016_gene146	1.3e-89	263.0	COG0432@1|root,COG0432@2|Bacteria,1RA5G@1224|Proteobacteria,42QZ8@68525|delta/epsilon subdivisions,2WMV9@28221|Deltaproteobacteria,2MJMB@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Uncharacterised protein family UPF0047	-	-	-	-	-	-	-	-	-	-	-	-	UPF0047
k59_200229_1	570268.ANBB01000033_gene2055	1.41e-16	80.9	COG0210@1|root,COG1379@1|root,COG0210@2|Bacteria,COG1379@2|Bacteria,2I12T@201174|Actinobacteria,4ENF0@85012|Streptosporangiales	201174|Actinobacteria	L	PFAM UvrD REP helicase	pcrA	-	-	-	-	-	-	-	-	-	-	-	UvrD-helicase,UvrD_C
k59_124778_1	1303518.CCALI_01593	7.51e-78	243.0	COG2084@1|root,COG2084@2|Bacteria	2|Bacteria	I	phosphogluconate dehydrogenase (decarboxylating) activity	yfjR	-	1.1.1.31	ko:K00020	ko00280,ko01100,map00280,map01100	-	R05066	RC00099	ko00000,ko00001,ko01000	-	-	-	NAD_binding_11,NAD_binding_2
k59_192610_1	102107.XP_008244695.1	2.25e-26	105.0	COG0537@1|root,KOG3275@2759|Eukaryota,37U5N@33090|Viridiplantae,3GI9V@35493|Streptophyta,4JP57@91835|fabids	35493|Streptophyta	T	Scavenger mRNA decapping enzyme C-term binding	-	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016787,GO:0016817,GO:0016819,GO:0019637,GO:0019693,GO:0034641,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0047627,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564	-	-	-	-	-	-	-	-	-	-	HIT
k59_185463_1	1232437.KL662077_gene1960	8.47e-22	87.8	COG2203@1|root,COG2203@2|Bacteria	2|Bacteria	T	Gaf domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,PAS_4
k59_200245_1	1121405.dsmv_2695	2.01e-78	247.0	COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,42M88@68525|delta/epsilon subdivisions,2WIZI@28221|Deltaproteobacteria,2MJ2S@213118|Desulfobacterales	28221|Deltaproteobacteria	T	PFAM sigma-54 factor interaction domain-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,PAS_9,Sigma54_activat
k59_185466_1	1265505.ATUG01000001_gene4046	5.46e-49	177.0	COG0642@1|root,COG4191@1|root,COG2205@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MC4@68525|delta/epsilon subdivisions,2WIU5@28221|Deltaproteobacteria,2MIV8@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS_9,Response_reg
k59_124788_1	439235.Dalk_0708	1.56e-88	280.0	COG0472@1|root,COG1086@1|root,COG0472@2|Bacteria,COG1086@2|Bacteria,1MWYW@1224|Proteobacteria,42NVY@68525|delta/epsilon subdivisions,2X5IH@28221|Deltaproteobacteria,2MQ3P@213118|Desulfobacterales	28221|Deltaproteobacteria	M	PFAM Glycosyl transferase family 4	-	-	2.7.8.33,2.7.8.35	ko:K02851	-	-	R08856	RC00002	ko00000,ko01000,ko01003,ko01005	-	-	-	CoA_binding_3,Glycos_transf_4
k59_116631_1	62977.ACIAD2026	0.000127	45.1	COG3049@1|root,COG3049@2|Bacteria,1MWPQ@1224|Proteobacteria,1RN43@1236|Gammaproteobacteria,3NJE7@468|Moraxellaceae	1236|Gammaproteobacteria	M	Linear amide C-N hydrolases, choloylglycine hydrolase family	cbh	-	3.5.1.24	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	-	R02797,R03975,R03977,R04486,R04487,R05835	RC00090,RC00096	ko00000,ko00001,ko01000	-	-	-	CBAH
k59_63867_1	933262.AXAM01000013_gene1289	1.93e-109	328.0	COG0773@1|root,COG0773@2|Bacteria,1MV68@1224|Proteobacteria,42MMP@68525|delta/epsilon subdivisions,2WK50@28221|Deltaproteobacteria,2MIR1@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Belongs to the MurCDEF family	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
k59_124791_1	713586.KB900536_gene589	1.17e-27	112.0	COG1073@1|root,COG1073@2|Bacteria,1RIWI@1224|Proteobacteria,1S0GF@1236|Gammaproteobacteria,1X0AW@135613|Chromatiales	135613|Chromatiales	S	Serine aminopeptidase, S33	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Hydrolase_4
k59_208069_1	243233.MCA1247	1.35e-52	181.0	COG0166@1|root,COG0166@2|Bacteria,1MUFP@1224|Proteobacteria,1RNIT@1236|Gammaproteobacteria,1XEDN@135618|Methylococcales	135618|Methylococcales	G	Belongs to the GPI family	pgi	-	5.3.1.9	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI
k59_40997_1	1123371.ATXH01000006_gene847	4.33e-07	51.6	COG0809@1|root,COG0809@2|Bacteria,2GH2H@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	J	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	queA	-	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
k59_40997_2	96561.Dole_0082	1.01e-18	78.6	COG3242@1|root,COG3242@2|Bacteria,1PKNQ@1224|Proteobacteria,42X3S@68525|delta/epsilon subdivisions,2X0TB@28221|Deltaproteobacteria,2MM97@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Uncharacterized protein conserved in bacteria (DUF2065)	-	-	-	ko:K09937	-	-	-	-	ko00000	-	-	-	DUF2065
k59_139748_1	1121405.dsmv_2792	2.96e-68	214.0	COG1102@1|root,COG1102@2|Bacteria,1N69V@1224|Proteobacteria,42UCK@68525|delta/epsilon subdivisions,2WQ7M@28221|Deltaproteobacteria,2MKKM@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Cytidylate kinase-like family	-	-	-	-	-	-	-	-	-	-	-	-	Cytidylate_kin2
k59_230690_1	177437.HRM2_14260	1.7e-67	231.0	COG2204@1|root,COG4191@1|root,COG2204@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MFW@68525|delta/epsilon subdivisions,2WKMP@28221|Deltaproteobacteria,2MI6S@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,PAS,Response_reg,dCache_1
k59_86326_1	102129.Lepto7375DRAFT_1521	2.66e-48	165.0	COG2008@1|root,COG2008@2|Bacteria,1G4PN@1117|Cyanobacteria	1117|Cyanobacteria	E	Threonine aldolase	-	-	4.1.2.48	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	-	R00751,R06171	RC00312,RC00372	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
k59_56333_1	159087.Daro_1690	1.16e-35	135.0	COG1903@1|root,COG1903@2|Bacteria,1MXU3@1224|Proteobacteria,2VITG@28216|Betaproteobacteria,2KUJC@206389|Rhodocyclales	206389|Rhodocyclales	H	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A	cbiD	-	2.1.1.195	ko:K02188	ko00860,ko01100,map00860,map01100	-	R07773	RC00003,RC02051	ko00000,ko00001,ko01000	-	-	-	CbiD
k59_192621_1	743836.AYNA01000025_gene2261	2.62e-47	167.0	COG1364@1|root,COG1364@2|Bacteria,1MU0T@1224|Proteobacteria,2TS98@28211|Alphaproteobacteria,36X82@31993|Methylocystaceae	28211|Alphaproteobacteria	E	ArgJ family	argJ	GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.3.1.1,2.3.1.35	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259,R02282	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	ArgJ
k59_124806_1	1392498.JQLH01000001_gene2108	1.66e-10	61.2	COG0568@1|root,COG0568@2|Bacteria,4NHJK@976|Bacteroidetes,1HZ9N@117743|Flavobacteriia,2PIIE@252356|Maribacter	976|Bacteroidetes	K	Sigma-70 region 3	-	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
k59_124806_2	1123240.ATVO01000004_gene1091	5.66e-07	52.0	COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,2UF6W@28211|Alphaproteobacteria,2JZZ2@204457|Sphingomonadales	204457|Sphingomonadales	K	Cold shock	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
k59_124806_3	4006.Lus10020953	1.15e-09	59.3	KOG0118@1|root,KOG0118@2759|Eukaryota,37JV2@33090|Viridiplantae,3GHCU@35493|Streptophyta,4JF1K@91835|fabids	35493|Streptophyta	A	Glycine-rich RNA-binding	-	GO:0000166,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005829,GO:0006950,GO:0008150,GO:0009266,GO:0009409,GO:0009628,GO:0036094,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0097159,GO:1901265,GO:1901363	-	ko:K12885	ko03040,map03040	-	-	-	ko00000,ko00001,ko03041	-	-	-	RRM_1,zf-CCHC
k59_185477_2	1279019.ARQK01000045_gene517	2.3e-15	77.8	COG1196@1|root,COG5283@1|root,COG1196@2|Bacteria,COG5283@2|Bacteria,1R97W@1224|Proteobacteria,1TK9M@1236|Gammaproteobacteria,1X0PG@135613|Chromatiales	135613|Chromatiales	D	Phage-related minor tail protein	-	-	-	-	-	-	-	-	-	-	-	-	PhageMin_Tail
k59_56340_2	1279009.ADICEAN_00261	2.95e-07	53.9	COG4099@1|root,COG4733@1|root,COG4099@2|Bacteria,COG4733@2|Bacteria,4NK2V@976|Bacteroidetes,47P6C@768503|Cytophagia	976|Bacteroidetes	G	PFAM Fibronectin type III domain	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,PA14,fn3
k59_185479_1	641491.DND132_2897	4.91e-50	175.0	COG0471@1|root,COG0471@2|Bacteria,1MU0K@1224|Proteobacteria,42MR7@68525|delta/epsilon subdivisions,2WIKA@28221|Deltaproteobacteria,2M9JU@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	PFAM Citrate transporter	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS,Na_sulph_symp,TrkA_C
k59_116654_1	1167006.UWK_03515	1.02e-37	138.0	COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,42MQI@68525|delta/epsilon subdivisions,2WN1S@28221|Deltaproteobacteria,2MJMW@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Aminotransferase class I and II	-	-	2.6.1.2	ko:K00814	ko00220,ko00250,ko00710,ko01100,ko01120,ko01200,ko01210,ko01230,map00220,map00250,map00710,map01100,map01120,map01200,map01210,map01230	M00171	R00258	RC00006,RC00008	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
k59_116654_2	641491.DND132_2498	8.66e-28	106.0	COG0607@1|root,COG0607@2|Bacteria,1R0JB@1224|Proteobacteria,42W7F@68525|delta/epsilon subdivisions,2WQ3E@28221|Deltaproteobacteria,2MC3S@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	SMART Rhodanese domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
k59_132066_1	1380394.JADL01000009_gene3208	5.13e-105	321.0	COG3264@1|root,COG3264@2|Bacteria,1MWSA@1224|Proteobacteria,2TRKK@28211|Alphaproteobacteria,2JPKF@204441|Rhodospirillales	204441|Rhodospirillales	M	COG3264 Small-conductance mechanosensitive channel	-	-	-	ko:K05802	-	-	-	-	ko00000,ko02000	1.A.23.1.1	-	-	DUF3772,MS_channel
k59_18127_1	317619.ANKN01000088_gene1120	3.79e-20	94.7	COG3437@1|root,COG3437@2|Bacteria	2|Bacteria	T	response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Response_reg
k59_116656_1	177437.HRM2_09080	6.63e-79	243.0	COG0388@1|root,COG0388@2|Bacteria,1MUUB@1224|Proteobacteria,42QTI@68525|delta/epsilon subdivisions,2WMRH@28221|Deltaproteobacteria,2MJMC@213118|Desulfobacterales	28221|Deltaproteobacteria	S	PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	-	-	3.5.1.3	ko:K13566	ko00250,map00250	-	R00269,R00348	RC00010	ko00000,ko00001,ko01000	-	-	-	CN_hydrolase
k59_132070_1	1167006.UWK_00627	1.52e-54	192.0	COG0574@1|root,COG3848@1|root,COG0574@2|Bacteria,COG3848@2|Bacteria,1MU0R@1224|Proteobacteria,42MW3@68525|delta/epsilon subdivisions,2WIXV@28221|Deltaproteobacteria,2MIGX@213118|Desulfobacterales	28221|Deltaproteobacteria	GT	pyruvate phosphate dikinase	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PPDK_N
k59_33444_1	1265505.ATUG01000003_gene341	3.12e-09	55.8	COG1908@1|root,COG1908@2|Bacteria,1RGF7@1224|Proteobacteria,42S3H@68525|delta/epsilon subdivisions,2WNTN@28221|Deltaproteobacteria,2MKRI@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Methyl-viologen-reducing hydrogenase, delta subunit	-	-	-	-	-	-	-	-	-	-	-	-	FlpD
k59_33444_2	1232437.KL662038_gene2288	1.32e-120	347.0	COG4656@1|root,COG4656@2|Bacteria,1MWAX@1224|Proteobacteria,42NJM@68525|delta/epsilon subdivisions,2WJJB@28221|Deltaproteobacteria,2MHNS@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Methylene-tetrahydrofolate reductase C terminal	-	-	-	-	-	-	-	-	-	-	-	-	MTHFR_C
k59_238221_1	237368.SCABRO_01657	1.24e-41	158.0	COG2114@1|root,COG4252@1|root,COG2114@2|Bacteria,COG4252@2|Bacteria,2IYZI@203682|Planctomycetes	203682|Planctomycetes	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	CHASE2,Guanylate_cyc
k59_86343_1	96561.Dole_0593	3.15e-26	108.0	COG1792@1|root,COG1792@2|Bacteria,1N8ZS@1224|Proteobacteria,42S9I@68525|delta/epsilon subdivisions,2WNTW@28221|Deltaproteobacteria,2MJMG@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Involved in formation and maintenance of cell shape	mreC	-	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
k59_86343_2	335543.Sfum_2592	8.04e-43	149.0	COG1077@1|root,COG1077@2|Bacteria,1MUMW@1224|Proteobacteria,42M1J@68525|delta/epsilon subdivisions,2WIQR@28221|Deltaproteobacteria,2MQB1@213462|Syntrophobacterales	28221|Deltaproteobacteria	D	TIGRFAM cell shape determining protein, MreB Mrl family	mreB	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
k59_192629_1	278963.ATWD01000001_gene3082	3.47e-05	51.6	COG0265@1|root,COG0265@2|Bacteria,3Y3HE@57723|Acidobacteria,2JHN5@204432|Acidobacteriia	204432|Acidobacteriia	O	peptidase S1 and S6 chymotrypsin Hap	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
k59_230714_1	883.DvMF_1911	1.37e-06	51.6	COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,42MTX@68525|delta/epsilon subdivisions,2WITE@28221|Deltaproteobacteria,2M8SG@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	Belongs to the DegT DnrJ EryC1 family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
k59_132072_1	1121403.AUCV01000026_gene2384	6.52e-13	70.1	COG0574@1|root,COG3848@1|root,COG0574@2|Bacteria,COG3848@2|Bacteria,1MU0R@1224|Proteobacteria,42MW3@68525|delta/epsilon subdivisions,2WIXV@28221|Deltaproteobacteria,2MIGX@213118|Desulfobacterales	28221|Deltaproteobacteria	GT	pyruvate phosphate dikinase	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PPDK_N
k59_132072_2	1322246.BN4_20089	3.3e-79	249.0	COG2453@1|root,COG2453@2|Bacteria,1R6EU@1224|Proteobacteria,42NUR@68525|delta/epsilon subdivisions,2WJKY@28221|Deltaproteobacteria,2M7YH@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	PFAM Dual specificity protein phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	DSPc
k59_63902_1	552811.Dehly_0336	7.05e-28	108.0	COG2120@1|root,COG2120@2|Bacteria,2G6FB@200795|Chloroflexi,34CVG@301297|Dehalococcoidia	301297|Dehalococcoidia	S	GlcNAc-PI de-N-acetylase	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
k59_215287_1	1056820.KB900696_gene4099	9.31e-37	131.0	COG0656@1|root,COG0656@2|Bacteria,1MWFS@1224|Proteobacteria,1RMX6@1236|Gammaproteobacteria,2PMK2@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	S	Aldo/keto reductase family	dkgA	GO:0003674,GO:0003824,GO:0004033,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0008106,GO:0008150,GO:0008152,GO:0009056,GO:0009438,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0042180,GO:0042182,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046185,GO:0051596,GO:0055114,GO:0071704,GO:1901575	1.1.1.346	ko:K06221	-	-	R08878	RC00089	ko00000,ko01000	-	-	iECH74115_1262.ECH74115_4323,iECSP_1301.ECSP_3988	Aldo_ket_red
k59_109094_1	1121447.JONL01000002_gene1996	3.01e-31	126.0	COG4782@1|root,COG4782@2|Bacteria,1PSSD@1224|Proteobacteria,430S8@68525|delta/epsilon subdivisions,2WW3H@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Alpha/beta hydrolase of unknown function (DUF900)	-	-	-	-	-	-	-	-	-	-	-	-	DUF900
k59_56365_1	234267.Acid_7639	3.48e-188	536.0	COG3344@1|root,COG3344@2|Bacteria,3Y46K@57723|Acidobacteria	57723|Acidobacteria	L	PFAM RNA-directed DNA polymerase (Reverse transcriptase)	-	-	2.7.7.49	ko:K00986	-	-	-	-	ko00000,ko01000	-	-	-	GIIM,RVT_1,RVT_N
k59_18146_1	522772.Dacet_0801	2.41e-85	266.0	COG2204@1|root,COG2204@2|Bacteria,2GF2T@200930|Deferribacteres	2|Bacteria	T	PFAM sigma-54 factor interaction domain-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
k59_33461_1	1094980.Mpsy_0890	1.56e-79	247.0	COG1405@1|root,arCOG01981@2157|Archaea,2XT0Z@28890|Euryarchaeota,2N96C@224756|Methanomicrobia	224756|Methanomicrobia	K	Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB)	tfb	-	-	ko:K03124	ko03022,ko05169,ko05203,map03022,map05169,map05203	-	-	-	ko00000,ko00001,ko03021	-	-	-	TFIIB,TF_Zn_Ribbon
k59_132085_1	344747.PM8797T_02329	5.59e-46	163.0	COG0025@1|root,COG0025@2|Bacteria,2IZBZ@203682|Planctomycetes	203682|Planctomycetes	P	Sodium/hydrogen exchanger family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
k59_155022_1	1197477.IA57_01720	5.67e-19	90.5	COG1216@1|root,COG1216@2|Bacteria,4PKGS@976|Bacteroidetes,1IJRT@117743|Flavobacteriia	976|Bacteroidetes	S	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
k59_71266_1	65393.PCC7424_1082	3.72e-138	432.0	COG0745@1|root,COG2202@1|root,COG2203@1|root,COG3829@1|root,COG5002@1|root,COG0745@2|Bacteria,COG2202@2|Bacteria,COG2203@2|Bacteria,COG3829@2|Bacteria,COG5002@2|Bacteria,1GHFQ@1117|Cyanobacteria,3KKU4@43988|Cyanothece	1117|Cyanobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K11527	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	GAF,GAF_2,HAMP,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg,dCache_1
k59_185490_1	1250278.JQNQ01000001_gene1673	7.95e-99	302.0	COG1409@1|root,COG1409@2|Bacteria,4NF9K@976|Bacteroidetes,1HY33@117743|Flavobacteriia	976|Bacteroidetes	S	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,MetallophosC,MetallophosN
k59_208112_1	388401.RB2150_02584	1.91e-79	246.0	COG2801@1|root,COG2963@1|root,COG2801@2|Bacteria,COG2963@2|Bacteria,1PBHA@1224|Proteobacteria,2TRQF@28211|Alphaproteobacteria,3ZI18@58840|unclassified Rhodobacteraceae	28211|Alphaproteobacteria	L	L COG2801 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	HTH_32,rve,rve_3
k59_56375_1	696281.Desru_1825	6.44e-47	154.0	COG3603@1|root,COG3603@2|Bacteria,1V9Y8@1239|Firmicutes,24JKN@186801|Clostridia,2663Q@186807|Peptococcaceae	186801|Clostridia	S	ACT domain	-	-	-	ko:K09707	-	-	-	-	ko00000	-	-	-	ACT_7
k59_71271_2	999547.KI421503_gene72	1.06e-28	107.0	COG2963@1|root,COG2963@2|Bacteria,1RHKX@1224|Proteobacteria,2U9TV@28211|Alphaproteobacteria,281TR@191028|Leisingera	28211|Alphaproteobacteria	L	Transposase	-	-	-	ko:K07483	-	-	-	-	ko00000	-	-	-	HTH_Tnp_1
k59_2918_1	264732.Moth_2268	2.9e-81	251.0	COG1063@1|root,COG1063@2|Bacteria,1TPWP@1239|Firmicutes,24ATV@186801|Clostridia,42FBE@68295|Thermoanaerobacterales	186801|Clostridia	C	PFAM Alcohol dehydrogenase GroES domain protein	-	-	1.1.1.14	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	M00014	R00875,R01896	RC00085,RC00102	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N
k59_20244_1	1121440.AUMA01000007_gene1286	1.5e-15	77.0	COG1212@1|root,COG1212@2|Bacteria,1MUUU@1224|Proteobacteria,42PTX@68525|delta/epsilon subdivisions,2WMQW@28221|Deltaproteobacteria,2M9T9@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria	kdsB	-	2.7.7.38	ko:K00979	ko00540,ko01100,map00540,map01100	M00063	R03351,R11396	RC00152,RC00910	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_3
k59_111511_1	161156.JQKW01000001_gene1470	7.67e-108	320.0	COG0725@1|root,COG0725@2|Bacteria,2GIAT@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	P	Bacterial extracellular solute-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_11
k59_233255_1	177437.HRM2_29520	2.07e-63	204.0	COG1721@1|root,COG1721@2|Bacteria,1Q7RR@1224|Proteobacteria,42PJB@68525|delta/epsilon subdivisions,2WK1X@28221|Deltaproteobacteria,2MJBE@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
k59_20246_1	350688.Clos_1491	4.75e-28	112.0	COG1360@1|root,COG1360@2|Bacteria,1V8KE@1239|Firmicutes,24GQQ@186801|Clostridia,36FHM@31979|Clostridiaceae	186801|Clostridia	N	PFAM OmpA MotB domain protein	motB	-	-	ko:K02557	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	MotB_plug,OmpA
k59_50420_1	1280686.AUKE01000014_gene644	4.09e-19	89.0	COG0526@1|root,COG0785@1|root,COG0526@2|Bacteria,COG0785@2|Bacteria,1VAPY@1239|Firmicutes,25B5Z@186801|Clostridia,4BYQG@830|Butyrivibrio	186801|Clostridia	CO	Cytochrome C biogenesis protein transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,DsbD,Redoxin
k59_42755_1	1232437.KL661960_gene3073	3.88e-78	246.0	COG0247@1|root,COG0247@2|Bacteria,1MUMH@1224|Proteobacteria,42N9U@68525|delta/epsilon subdivisions,2WINY@28221|Deltaproteobacteria,2MHR0@213118|Desulfobacterales	28221|Deltaproteobacteria	C	4Fe-4S dicluster domain	tmcB	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_17,Fer4_8
k59_210355_1	335543.Sfum_3616	9.11e-48	170.0	COG2304@1|root,COG2304@2|Bacteria,1MUTS@1224|Proteobacteria,42R8X@68525|delta/epsilon subdivisions,2WN6U@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	von Willebrand factor, type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA
k59_111516_1	192952.MM_1417	9.7e-45	161.0	COG0527@1|root,arCOG00861@2157|Archaea,2XTJ0@28890|Euryarchaeota,2N91C@224756|Methanomicrobia	224756|Methanomicrobia	E	Belongs to the aspartokinase family	lysC	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT,ACT_7
k59_58806_1	1041147.AUFB01000094_gene5706	2.22e-73	233.0	COG3344@1|root,COG3344@2|Bacteria,1MVI1@1224|Proteobacteria,2U1Z0@28211|Alphaproteobacteria,4BMWU@82115|Rhizobiaceae	28211|Alphaproteobacteria	L	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	2.7.7.49	ko:K00986,ko:K15342	-	-	-	-	ko00000,ko01000,ko02048,ko03400	-	-	-	Cas_Cas1,GIIM,RVT_1
k59_81366_1	439235.Dalk_0774	6.52e-33	128.0	COG0322@1|root,COG0322@2|Bacteria,1MV38@1224|Proteobacteria,42MB1@68525|delta/epsilon subdivisions,2WJ76@28221|Deltaproteobacteria,2MIHC@213118|Desulfobacterales	28221|Deltaproteobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:1902494,GO:1905347,GO:1905348,GO:1990391	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N
k59_148823_1	933262.AXAM01000003_gene2794	1.29e-69	219.0	COG0331@1|root,COG0331@2|Bacteria,1MV6N@1224|Proteobacteria,42MKH@68525|delta/epsilon subdivisions,2WIWQ@28221|Deltaproteobacteria,2MI91@213118|Desulfobacterales	28221|Deltaproteobacteria	I	TIGRFAM malonyl CoA-acyl carrier protein transacylase	fabD	-	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
k59_164248_1	626939.HMPREF9443_01838	8.32e-87	275.0	COG0129@1|root,COG0129@2|Bacteria,1TP1R@1239|Firmicutes,4H2IM@909932|Negativicutes	909932|Negativicutes	EG	Belongs to the IlvD Edd family	ilvD	-	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
k59_4499_2	1304885.AUEY01000047_gene77	2.64e-123	362.0	COG0849@1|root,COG0849@2|Bacteria,1MUSR@1224|Proteobacteria,42MS2@68525|delta/epsilon subdivisions,2WIQ0@28221|Deltaproteobacteria,2MHV9@213118|Desulfobacterales	28221|Deltaproteobacteria	D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring	ftsA	-	-	ko:K03590	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036,ko04812	-	-	-	FtsA,SHS2_FTSA
k59_217461_1	339860.Msp_0171	1.69e-29	121.0	COG0495@1|root,arCOG00809@2157|Archaea,2XU7M@28890|Euryarchaeota,23NV4@183925|Methanobacteria	183925|Methanobacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	-	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1
k59_179257_1	335543.Sfum_2956	9.91e-130	391.0	COG1523@1|root,COG1523@2|Bacteria,1MU19@1224|Proteobacteria,42P3J@68525|delta/epsilon subdivisions,2WKFS@28221|Deltaproteobacteria,2MQ9F@213462|Syntrophobacterales	28221|Deltaproteobacteria	G	Belongs to the glycosyl hydrolase 13 family	-	-	3.2.1.68	ko:K01214	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R09995,R11261	-	ko00000,ko00001,ko00002,ko01000	-	CBM48,GH13	-	Alpha-amylase,CBM_48
k59_96373_1	643648.Slip_1786	6.32e-39	144.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,1TNZE@1239|Firmicutes,2480H@186801|Clostridia,42JJQ@68298|Syntrophomonadaceae	186801|Clostridia	H	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	ACPS,Carb_kinase,YjeF_N
k59_42774_1	1191523.MROS_2097	2.04e-62	201.0	COG0407@1|root,COG0407@2|Bacteria	2|Bacteria	H	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III	-	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
k59_27535_1	933262.AXAM01000159_gene2160	6.44e-135	396.0	COG2986@1|root,COG2986@2|Bacteria,1MU6K@1224|Proteobacteria,42MST@68525|delta/epsilon subdivisions,2WKAN@28221|Deltaproteobacteria,2MIWB@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Aromatic amino acid lyase	hutH	-	4.3.1.3	ko:K01745	ko00340,ko01100,map00340,map01100	M00045	R01168	RC00361	ko00000,ko00001,ko00002,ko01000	-	-	-	Lyase_aromatic
k59_73683_1	555779.Dthio_PD1739	6.32e-42	145.0	2DB88@1|root,2Z7QT@2|Bacteria,1R0WJ@1224|Proteobacteria,42RMG@68525|delta/epsilon subdivisions,2WNWJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4338)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4338
k59_148830_1	1232437.KL662068_gene2785	1.01e-29	120.0	COG0697@1|root,COG0697@2|Bacteria,1R6KH@1224|Proteobacteria,42SGW@68525|delta/epsilon subdivisions,2WPC6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
k59_194347_1	289376.THEYE_A0011	1.33e-67	215.0	COG1212@1|root,COG1212@2|Bacteria,3J0NR@40117|Nitrospirae	40117|Nitrospirae	M	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria	kdsB	-	2.7.7.38	ko:K00979	ko00540,ko01100,map00540,map01100	M00063	R03351,R11396	RC00152,RC00910	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_3
k59_142094_1	1121405.dsmv_1877	2.01e-110	333.0	COG0318@1|root,COG0318@2|Bacteria,1MUMC@1224|Proteobacteria,42NT5@68525|delta/epsilon subdivisions,2WIWR@28221|Deltaproteobacteria,2MHQV@213118|Desulfobacterales	28221|Deltaproteobacteria	IQ	PFAM AMP-dependent synthetase and ligase	alkK	-	6.2.1.3	ko:K00666,ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
k59_134567_1	485915.Dret_0776	2.96e-64	211.0	COG2204@1|root,COG2204@2|Bacteria,1MVWX@1224|Proteobacteria,42MIB@68525|delta/epsilon subdivisions,2WJQK@28221|Deltaproteobacteria,2M80M@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	two component, sigma54 specific, transcriptional regulator	-	-	-	ko:K02481	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Sigma54_activat
k59_118628_1	247634.GPB2148_1603	1.72e-38	139.0	COG0584@1|root,COG0584@2|Bacteria,1QHQ6@1224|Proteobacteria,1S8CK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	glycerophosphoryl diester phosphodiesterase	avrBs2	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
k59_50462_1	1539298.JO41_00275	7.72e-25	108.0	COG4666@1|root,COG4666@2|Bacteria,2J57Z@203691|Spirochaetes	203691|Spirochaetes	S	TIGRFAM TRAP transporter, 4TM 12TM fusion protein	-	-	-	-	-	-	-	-	-	-	-	-	DctM
k59_142107_1	1443125.Z962_03015	8.62e-25	99.4	COG2110@1|root,COG2110@2|Bacteria,1TPCU@1239|Firmicutes,24ARG@186801|Clostridia,36J60@31979|Clostridiaceae	186801|Clostridia	S	Appr-1-p processing	ymdB	-	-	-	-	-	-	-	-	-	-	-	Macro
k59_142107_3	1041147.AUFB01000023_gene5140	9.81e-17	79.3	COG0483@1|root,COG0483@2|Bacteria,1MUQT@1224|Proteobacteria,2TR06@28211|Alphaproteobacteria,4B8R5@82115|Rhizobiaceae	28211|Alphaproteobacteria	G	Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family	suhB	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
k59_4516_1	879212.DespoDRAFT_02931	3.64e-42	150.0	28J8Y@1|root,2Z943@2|Bacteria,1REXC@1224|Proteobacteria	1224|Proteobacteria	S	Domain of unknown function (DUF4338)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4338
k59_50477_1	1124780.ANNU01000003_gene1398	1.12e-77	246.0	COG4198@1|root,COG4198@2|Bacteria,4NGQH@976|Bacteroidetes,47NI5@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF1015)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1015
k59_134600_1	933262.AXAM01000054_gene2658	1.12e-89	280.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,42M51@68525|delta/epsilon subdivisions,2WIPP@28221|Deltaproteobacteria,2MHPE@213118|Desulfobacterales	28221|Deltaproteobacteria	NU	type II secretion system protein E	-	-	-	-	-	-	-	-	-	-	-	-	T2SSE,T2SSE_N
k59_157144_2	324925.Ppha_2419	1.32e-44	151.0	COG1432@1|root,COG1432@2|Bacteria,1FECY@1090|Chlorobi	1090|Chlorobi	NU	OST-HTH/LOTUS domain	-	-	-	-	-	-	-	-	-	-	-	-	NYN,OST-HTH
k59_164265_1	768710.DesyoDRAFT_3378	1.24e-19	86.7	COG5012@1|root,COG5012@2|Bacteria,1V1DJ@1239|Firmicutes,24GX9@186801|Clostridia	186801|Clostridia	S	TIGRFAM methyltransferase cognate corrinoid proteins, Methanosarcina family	-	-	-	ko:K14084	ko00680,ko01120,ko01200,map00680,map01120,map01200	M00563	R09124	RC00035,RC00732,RC02984	ko00000,ko00001,ko00002	-	-	-	B12-binding,B12-binding_2
k59_164265_2	1123288.SOV_2c07540	5.25e-12	68.6	arCOG05143@1|root,2Z8AM@2|Bacteria,1TSB3@1239|Firmicutes,4H7XQ@909932|Negativicutes	909932|Negativicutes	S	Monomethylamine methyltransferase MtmB	mtmB	-	2.1.1.248	ko:K16176	ko00680,ko01120,ko01200,map00680,map01120,map01200	M00563	R09998,R10014	RC00035,RC01144,RC02985	ko00000,ko00001,ko00002,ko01000	-	-	-	MtmB
k59_42805_1	631454.N177_1637	4.39e-51	175.0	COG1149@1|root,COG1149@2|Bacteria,1QTYV@1224|Proteobacteria,2TTH3@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	TIGRFAM CitB domain protein	tcuB	-	-	ko:K13795	-	-	-	-	ko00000	-	-	-	-
k59_126984_1	1249997.JHZW01000002_gene207	9.06e-08	54.7	COG1225@1|root,COG1225@2|Bacteria,4NKV2@976|Bacteroidetes,1IGH9@117743|Flavobacteriia,2PI05@252356|Maribacter	976|Bacteroidetes	O	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
k59_126984_2	706587.Desti_1769	4.48e-25	100.0	COG1225@1|root,COG1225@2|Bacteria,1MWFZ@1224|Proteobacteria,42SCA@68525|delta/epsilon subdivisions,2WP2G@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
k59_58854_1	1265505.ATUG01000001_gene3058	2.03e-70	229.0	2C99Z@1|root,2Z9YV@2|Bacteria,1N0B7@1224|Proteobacteria,42P3M@68525|delta/epsilon subdivisions,2WN6Z@28221|Deltaproteobacteria,2MMGX@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF3373)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3373
k59_96379_1	304371.MCP_2382	3.67e-50	174.0	COG0438@1|root,arCOG01403@2157|Archaea,2Y8B9@28890|Euryarchaeota,2NAKA@224756|Methanomicrobia	224756|Methanomicrobia	M	Starch synthase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
k59_42813_1	399549.Msed_0415	8.05e-07	55.8	COG1233@1|root,COG1902@1|root,arCOG00615@2157|Archaea,arCOG01521@2157|Archaea	2157|Archaea	Q	COG1233 Phytoene dehydrogenase and related proteins	fmn	-	1.14.13.40,4.2.1.53	ko:K09461,ko:K10254,ko:K10680	ko00627,ko00633,ko01120,map00627,map00633,map01120	-	R03998,R03999,R08014,R08017,R08042	RC00244,RC00250	ko00000,ko00001,ko01000	-	-	-	Amino_oxidase,MCRA,NAD_binding_8,Oxidored_FMN
k59_224881_1	526222.Desal_3560	4.42e-117	343.0	COG1073@1|root,COG1073@2|Bacteria,1MUCD@1224|Proteobacteria,42NEK@68525|delta/epsilon subdivisions,2WJPT@28221|Deltaproteobacteria,2M87E@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Dienelactone hydrolase family	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	DLH,Peptidase_S15
k59_195046_1	1121405.dsmv_2119	9.01e-106	330.0	COG0466@1|root,COG0466@2|Bacteria,1MUV2@1224|Proteobacteria,42M9W@68525|delta/epsilon subdivisions,2WJ29@28221|Deltaproteobacteria,2MIDR@213118|Desulfobacterales	28221|Deltaproteobacteria	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon-3	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
k59_59546_1	1131269.AQVV01000008_gene970	1.7e-34	127.0	COG2077@1|root,COG2077@2|Bacteria	2|Bacteria	O	thioredoxin peroxidase activity	tpx	-	1.11.1.15	ko:K11065	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA,Redoxin
k59_74331_2	1122918.KB907284_gene1186	3.49e-17	82.0	COG0382@1|root,COG0382@2|Bacteria,1TQU5@1239|Firmicutes,4HAGP@91061|Bacilli,26R65@186822|Paenibacillaceae	91061|Bacilli	H	4-hydroxybenzoate polyprenyltransferase	ubiA	-	2.5.1.39	ko:K03179	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R05000,R05615	RC00209,RC02895	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
k59_28252_1	1225184.ALXE01000029_gene1549	7.7e-31	125.0	COG0043@1|root,COG0043@2|Bacteria,1PZMY@1224|Proteobacteria,1S199@1236|Gammaproteobacteria,3W2VB@53335|Pantoea	1236|Gammaproteobacteria	H	3-octaprenyl-4-hydroxybenzoate carboxy-lyase	-	-	4.1.1.98	ko:K03182	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04985,R04986	RC00391	ko00000,ko00001,ko00002,ko01000	-	-	-	UbiD
k59_36602_1	1121912.AUHD01000009_gene3776	2.47e-13	73.2	COG0451@1|root,COG0451@2|Bacteria,4NI4C@976|Bacteroidetes,1HYXU@117743|Flavobacteriia	976|Bacteroidetes	M	Male sterility protein	-	-	-	-	-	-	-	-	-	-	-	-	3Beta_HSD,Epimerase
k59_135359_1	1463864.JOGO01000085_gene4284	2.9e-20	91.7	COG0411@1|root,COG0411@2|Bacteria,2GMEE@201174|Actinobacteria	201174|Actinobacteria	E	ABC transporter	livG	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
k59_135359_2	1125863.JAFN01000001_gene3442	3.96e-12	67.4	COG4177@1|root,COG4177@2|Bacteria,1PTVX@1224|Proteobacteria,42Q12@68525|delta/epsilon subdivisions,2WKBF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
k59_112400_1	1265505.ATUG01000002_gene1473	3.93e-68	231.0	COG0574@1|root,COG0745@1|root,COG0574@2|Bacteria,COG0745@2|Bacteria,1N38V@1224|Proteobacteria,42MWC@68525|delta/epsilon subdivisions,2WKAZ@28221|Deltaproteobacteria,2MICZ@213118|Desulfobacterales	28221|Deltaproteobacteria	GT	pyruvate phosphate dikinase	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_2,PPDK_N
k59_5144_1	1121022.ABENE_13040	3.52e-09	61.6	COG5659@1|root,COG5659@2|Bacteria,1MWAV@1224|Proteobacteria,2U2Q3@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_5
k59_59553_1	1259795.ARJK01000002_gene417	1.6e-29	114.0	COG0745@1|root,COG0745@2|Bacteria,1TPQG@1239|Firmicutes,248Z4@186801|Clostridia,42ESX@68295|Thermoanaerobacterales	186801|Clostridia	K	Response regulator receiver	-	-	-	ko:K07667,ko:K07668,ko:K07776	ko02020,ko02024,map02020,map02024	M00443,M00454,M00459	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
k59_225717_1	1121405.dsmv_2735	4.47e-93	283.0	COG0618@1|root,COG0618@2|Bacteria,1RAUQ@1224|Proteobacteria,42RKG@68525|delta/epsilon subdivisions,2WN0X@28221|Deltaproteobacteria,2MJ6U@213118|Desulfobacterales	28221|Deltaproteobacteria	S	PFAM phosphoesterase RecJ domain protein	-	-	3.1.13.3,3.1.3.7	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
k59_240850_1	1265505.ATUG01000003_gene578	2.5e-111	325.0	COG2801@1|root,COG2801@2|Bacteria,1MZ45@1224|Proteobacteria,42MM6@68525|delta/epsilon subdivisions,2WJ53@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	PFAM Integrase catalytic region	-	-	-	-	-	-	-	-	-	-	-	-	HTH_29,rve
k59_5147_1	1121430.JMLG01000003_gene507	5.48e-16	78.2	COG1545@1|root,COG3425@1|root,COG1545@2|Bacteria,COG3425@2|Bacteria,1UDNN@1239|Firmicutes,24DF4@186801|Clostridia,263HP@186807|Peptococcaceae	186801|Clostridia	I	DUF35 OB-fold domain, acyl-CoA-associated	-	-	2.3.3.10	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	M00088,M00095	R01978	RC00004,RC00503	ko00000,ko00001,ko00002,ko01000	-	-	-	ACP_syn_III_C,DUF35_N,OB_aCoA_assoc
k59_218210_2	272123.Anacy_3440	1.4e-17	90.5	COG4249@1|root,COG4249@2|Bacteria	2|Bacteria	S	B-1 B cell differentiation	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,Peptidase_C14
k59_74342_1	247490.KSU1_C1309	1.23e-105	325.0	COG5421@1|root,COG5421@2|Bacteria,2J33B@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_164914_1	1167006.UWK_00961	1.25e-61	199.0	COG0765@1|root,COG0765@2|Bacteria,1R4RU@1224|Proteobacteria,42PW7@68525|delta/epsilon subdivisions,2WK9J@28221|Deltaproteobacteria,2MJID@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02029	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	BPD_transp_1
k59_127610_1	104355.XP_007871309.1	8.56e-21	83.2	2E1I0@1|root,2S8UZ@2759|Eukaryota,3A9DK@33154|Opisthokonta,3Q6KM@4751|Fungi,3V5DS@5204|Basidiomycota	4751|Fungi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_127610_2	6211.A0A068Y3R8	1.26e-20	89.4	2DZJG@1|root,2S72Z@2759|Eukaryota	2759|Eukaryota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_127610_3	6211.A0A068Y139	8.11e-15	74.7	2DZJG@1|root,2S72Z@2759|Eukaryota	2759|Eukaryota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_14212_1	335543.Sfum_0309	9.84e-25	101.0	COG0517@1|root,COG0517@2|Bacteria,1RA25@1224|Proteobacteria,42R80@68525|delta/epsilon subdivisions,2WMW6@28221|Deltaproteobacteria,2MRHW@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	PFAM CBS domain	-	-	-	ko:K04767	-	-	-	-	ko00000	-	-	-	CBS
k59_14212_2	1121439.dsat_1410	1.13e-33	128.0	COG0683@1|root,COG0683@2|Bacteria,1MWR8@1224|Proteobacteria,42NI3@68525|delta/epsilon subdivisions,2WJ6P@28221|Deltaproteobacteria,2M856@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	PFAM Extracellular ligand-binding receptor	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_6
k59_211147_1	335543.Sfum_2305	1.19e-43	156.0	COG0683@1|root,COG0683@2|Bacteria,1MWJ1@1224|Proteobacteria,42MSJ@68525|delta/epsilon subdivisions,2WMCE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	PFAM Extracellular ligand-binding receptor	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_6
k59_74346_1	335543.Sfum_2466	2.46e-129	390.0	COG1042@1|root,COG1042@2|Bacteria,1MW98@1224|Proteobacteria,42KZW@68525|delta/epsilon subdivisions,2WIQB@28221|Deltaproteobacteria,2MR9S@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	CoA binding domain	-	-	6.2.1.13	ko:K01905,ko:K22224	ko00010,ko00620,ko00640,ko01100,ko01120,map00010,map00620,map00640,map01100,map01120	-	R00229,R00920	RC00004,RC00012,RC00014	ko00000,ko00001,ko01000,ko01004	-	-	-	ATP-grasp_5,CoA_binding_2,Succ_CoA_lig
k59_157830_1	1125863.JAFN01000001_gene3206	1.53e-15	76.6	COG2159@1|root,COG2159@2|Bacteria,1QZ3W@1224|Proteobacteria,42PKB@68525|delta/epsilon subdivisions,2WM59@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	PFAM transposase, IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_4
k59_157830_2	1125863.JAFN01000001_gene3206	5.34e-10	59.7	COG2159@1|root,COG2159@2|Bacteria,1QZ3W@1224|Proteobacteria,42PKB@68525|delta/epsilon subdivisions,2WM59@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	PFAM transposase, IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_4
k59_240869_1	1121405.dsmv_0962	5.6e-82	258.0	COG0342@1|root,COG0342@2|Bacteria,1MV5U@1224|Proteobacteria,42M6V@68525|delta/epsilon subdivisions,2WJCI@28221|Deltaproteobacteria,2MHS8@213118|Desulfobacterales	28221|Deltaproteobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
k59_157836_1	936136.ARRT01000006_gene4700	1.32e-09	64.3	COG0493@1|root,COG0493@2|Bacteria,1MU2H@1224|Proteobacteria,2TQK5@28211|Alphaproteobacteria,4B7WJ@82115|Rhizobiaceae	28211|Alphaproteobacteria	E	dihydropyrimidine dehydrogenase	preT	-	1.3.1.1	ko:K17722	ko00240,ko00410,ko00770,ko01100,map00240,map00410,map00770,map01100	M00046	R00977,R01414,R11026	RC00072,RC00123	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4_20,Pyr_redox_2
k59_149642_3	1313421.JHBV01000041_gene3449	3.76e-14	73.6	COG1480@1|root,COG1480@2|Bacteria,4NEHV@976|Bacteroidetes,1IPKB@117747|Sphingobacteriia	976|Bacteroidetes	S	7TM receptor with intracellular HD hydrolase	-	-	-	ko:K07037	-	-	-	-	ko00000	-	-	-	7TM-7TMR_HD,7TMR-HDED,HD
k59_74362_1	2002.JOEQ01000005_gene3672	3.05e-07	60.1	COG0421@1|root,COG0421@2|Bacteria,2I3HX@201174|Actinobacteria,4EHKS@85012|Streptosporangiales	201174|Actinobacteria	E	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	-	-	-	-	-	-	-	-	-	-	-	-	Spermine_synth
k59_172882_1	1499967.BAYZ01000164_gene6691	7.58e-83	261.0	COG0110@1|root,COG0673@1|root,COG0110@2|Bacteria,COG0673@2|Bacteria,2NP38@2323|unclassified Bacteria	2|Bacteria	S	Oxidoreductase family, NAD-binding Rossmann fold	wbpD	-	2.3.1.201	ko:K13018	ko00520,map00520	-	R10100	RC00004,RC00166	ko00000,ko00001,ko01000,ko01005	-	-	-	GFO_IDH_MocA,Hexapep,Hexapep_2
k59_234070_2	1121918.ARWE01000001_gene2240	8.42e-29	107.0	COG1359@1|root,COG1359@2|Bacteria,1N2BB@1224|Proteobacteria,42ZU2@68525|delta/epsilon subdivisions,2WVEC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_225766_1	1196323.ALKF01000187_gene5750	1.85e-12	68.6	COG1024@1|root,COG1024@2|Bacteria,1TQ89@1239|Firmicutes,4HCH3@91061|Bacilli,26VPR@186822|Paenibacillaceae	91061|Bacilli	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
k59_139352_1	565045.NOR51B_1564	2.19e-52	177.0	COG3288@1|root,COG3288@2|Bacteria,1MVXU@1224|Proteobacteria,1RN23@1236|Gammaproteobacteria,1J4FV@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	NAD(P) transhydrogenase, alpha subunit	pntA	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006740,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008746,GO:0008750,GO:0009117,GO:0009987,GO:0016020,GO:0016021,GO:0016491,GO:0016651,GO:0016652,GO:0019362,GO:0019637,GO:0031224,GO:0031226,GO:0034641,GO:0036094,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0046483,GO:0046496,GO:0046983,GO:0048037,GO:0050661,GO:0050662,GO:0051186,GO:0051287,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072524,GO:0097159,GO:1901265,GO:1901360,GO:1901363,GO:1901564	1.6.1.2	ko:K00324	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	iEcE24377_1341.EcE24377A_1810	AlaDh_PNT_C,AlaDh_PNT_N,PNTB_4TM
k59_40647_1	366649.XFF4834R_chr40110	5.97e-71	231.0	COG3519@1|root,COG3519@2|Bacteria,1MUY4@1224|Proteobacteria,1RPK4@1236|Gammaproteobacteria,1X4C2@135614|Xanthomonadales	135614|Xanthomonadales	S	type VI secretion protein	-	-	-	ko:K11896	-	M00334	-	-	ko00000,ko00002,ko02044	3.A.23.1	-	-	T6SS_TssF
k59_40647_2	1234364.AMSF01000056_gene1199	2.45e-51	168.0	COG3518@1|root,COG3518@2|Bacteria,1RF51@1224|Proteobacteria,1S7ZZ@1236|Gammaproteobacteria,1X6RV@135614|Xanthomonadales	135614|Xanthomonadales	S	Gene 25-like lysozyme	-	-	-	ko:K11897	-	M00334	-	-	ko00000,ko00002,ko02044	-	-	-	GPW_gp25
k59_70821_1	690850.Desaf_2484	6.14e-54	174.0	COG2391@1|root,COG2391@2|Bacteria,1RDQK@1224|Proteobacteria,42RU6@68525|delta/epsilon subdivisions,2WNJT@28221|Deltaproteobacteria,2MBSU@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Sulphur transport	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
k59_70821_2	999411.HMPREF1092_02141	0.000245	45.8	COG0454@1|root,COG0456@2|Bacteria,1V6KU@1239|Firmicutes,24J9Z@186801|Clostridia,36JIM@31979|Clostridiaceae	186801|Clostridia	K	This enzyme acetylates the N-terminal alanine of ribosomal protein S18	rimI	-	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1,Acetyltransf_10
k59_116184_1	279238.Saro_3022	3.77e-36	130.0	2C0VP@1|root,32ZQ9@2|Bacteria,1NENB@1224|Proteobacteria,2UGGI@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_70825_1	1134912.AJTV01000023_gene2878	3.07e-50	176.0	COG1538@1|root,COG1538@2|Bacteria,1MUA8@1224|Proteobacteria,2TSN8@28211|Alphaproteobacteria,36Y6U@31993|Methylocystaceae	28211|Alphaproteobacteria	MU	Outer membrane efflux protein	oprN	-	-	ko:K18300,ko:K19593	-	M00641,M00769	-	-	ko00000,ko00002,ko01504,ko02000	1.B.17,2.A.6.2.34	-	-	OEP
k59_85934_1	326427.Cagg_2210	3.45e-91	287.0	COG2766@1|root,COG2766@2|Bacteria,2G65T@200795|Chloroflexi,3756U@32061|Chloroflexia	32061|Chloroflexia	T	PFAM PrkA serine kinase	-	-	-	ko:K07180	-	-	-	-	ko00000	-	-	-	AAA_PrkA,PrkA
k59_223185_2	1121447.JONL01000003_gene2980	1.67e-09	65.9	COG0642@1|root,COG0642@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,42M0Y@68525|delta/epsilon subdivisions,2WIR4@28221|Deltaproteobacteria,2M7T3@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,PAS,PAS_9,Response_reg
k59_155040_1	443143.GM18_2768	8.67e-53	184.0	COG4584@1|root,COG4584@2|Bacteria,1MW5J@1224|Proteobacteria,42X93@68525|delta/epsilon subdivisions,2WSXR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	PFAM Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	rve
k59_2925_1	316067.Geob_0774	3.37e-73	241.0	COG0768@1|root,COG0768@2|Bacteria,1MUNY@1224|Proteobacteria,42M1T@68525|delta/epsilon subdivisions,2WK0W@28221|Deltaproteobacteria,43TGP@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Penicillin-binding protein, dimerisation domain	ftsI	-	3.4.16.4	ko:K03587	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PASTA,PBP_dimer,Transpeptidase
k59_230751_1	335543.Sfum_1217	9.86e-68	219.0	COG3635@1|root,COG3635@2|Bacteria,1R4TM@1224|Proteobacteria,42NCT@68525|delta/epsilon subdivisions,2WKEG@28221|Deltaproteobacteria,2MQ6B@213462|Syntrophobacterales	28221|Deltaproteobacteria	G	Proposed homoserine kinase	apgM	-	5.4.2.12	ko:K15635	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,PhosphMutase
k59_109130_1	933262.AXAM01000034_gene1563	1.21e-16	88.6	COG2885@1|root,COG3267@1|root,COG2885@2|Bacteria,COG3267@2|Bacteria,1MU3G@1224|Proteobacteria,42PJ3@68525|delta/epsilon subdivisions,2WJF6@28221|Deltaproteobacteria,2MJ4S@213118|Desulfobacterales	28221|Deltaproteobacteria	MU	AAA domain	-	-	-	ko:K02450	-	M00331	-	-	ko00000,ko00002,ko02044	9.B.42	-	-	AAA_22,OmpA
k59_94124_1	1459636.NTE_01453	1.92e-52	173.0	arCOG05906@1|root,arCOG05906@2157|Archaea,41T21@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_33496_1	335543.Sfum_3470	1.33e-167	482.0	COG0773@1|root,COG0773@2|Bacteria,1MV68@1224|Proteobacteria,42MMP@68525|delta/epsilon subdivisions,2WK50@28221|Deltaproteobacteria,2MR03@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	Belongs to the MurCDEF family	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
k59_101989_1	555779.Dthio_PD2105	2.03e-49	167.0	COG3677@1|root,COG3677@2|Bacteria,1MXYX@1224|Proteobacteria,43B03@68525|delta/epsilon subdivisions,2X6E6@28221|Deltaproteobacteria,2MH1Y@213115|Desulfovibrionales	28221|Deltaproteobacteria	L	Transposase zinc-ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS1595,Zn_Tnp_IS1595
k59_109134_1	515635.Dtur_1383	9.56e-25	103.0	COG0209@1|root,COG0209@2|Bacteria	2|Bacteria	F	ribonucleoside-diphosphate reductase activity	nrdZ	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	LAGLIDADG_3,Ribonuc_red_lgC,Ribonuc_red_lgN,TSCPD
k59_139816_1	283699.D172_2061	2.4e-39	154.0	COG3523@1|root,COG3523@2|Bacteria,1MV3D@1224|Proteobacteria,1RPQ2@1236|Gammaproteobacteria,2Q1SA@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	S	ImcF-related N-terminal domain	icmF	-	-	ko:K11891	ko02025,ko03070,map02025,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	IcmF-related,IcmF_C,ImcF-related_N
k59_10849_1	1408473.JHXO01000007_gene732	1.53e-18	81.3	COG2210@1|root,COG2210@2|Bacteria,4PNG4@976|Bacteroidetes,2FS0V@200643|Bacteroidia	976|Bacteroidetes	O	DsrE/DsrF/DrsH-like family	-	-	-	-	-	-	-	-	-	-	-	-	DrsE_2
k59_10849_2	575609.HMPREF0629_01439	3.34e-09	59.3	COG0446@1|root,COG0607@1|root,COG2210@1|root,COG0446@2|Bacteria,COG0607@2|Bacteria,COG2210@2|Bacteria,1TPWW@1239|Firmicutes,2484C@186801|Clostridia,22H02@1570339|Peptoniphilaceae	186801|Clostridia	C	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain	cdr	-	-	-	-	-	-	-	-	-	-	-	DrsE_2,Pyr_redox_2,Pyr_redox_dim,Rhodanese,TusA
k59_200326_1	933262.AXAM01000005_gene2509	4.02e-85	270.0	COG1298@1|root,COG1298@2|Bacteria,1MUF3@1224|Proteobacteria,42NB2@68525|delta/epsilon subdivisions,2WIWG@28221|Deltaproteobacteria,2MI0U@213118|Desulfobacterales	28221|Deltaproteobacteria	N	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin	flhA	-	-	ko:K02400	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	FHIPEP
k59_162427_1	335541.Swol_1053	2.9e-22	95.9	COG4936@1|root,COG4936@2|Bacteria	2|Bacteria	KT	Sensory domain found in PocR	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,MEDS,PAS,PAS_3,PAS_4,PAS_9,PocR,Response_reg
k59_139822_1	96561.Dole_0073	7.64e-73	227.0	COG0074@1|root,COG0074@2|Bacteria,1MUGA@1224|Proteobacteria,42M2W@68525|delta/epsilon subdivisions,2WJBV@28221|Deltaproteobacteria,2MJ9I@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit	sucD	-	6.2.1.5	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,CoA_binding,Ligase_CoA
k59_230765_1	1123373.ATXI01000010_gene1044	1.71e-80	251.0	COG0082@1|root,COG0082@2|Bacteria,2GGRE@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	-	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_synt
k59_94135_1	335543.Sfum_1059	2.35e-170	487.0	COG1900@1|root,COG1900@2|Bacteria,1P1MT@1224|Proteobacteria,42M1I@68525|delta/epsilon subdivisions,2WIQ2@28221|Deltaproteobacteria,2MQT8@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Homocysteine biosynthesis enzyme, sulfur-incorporation	-	-	-	-	-	-	-	-	-	-	-	-	HcyBio
k59_147070_1	933262.AXAM01000002_gene508	2.19e-92	294.0	COG1480@1|root,COG1480@2|Bacteria,1NCY5@1224|Proteobacteria,42MI9@68525|delta/epsilon subdivisions,2WJI1@28221|Deltaproteobacteria,2MI01@213118|Desulfobacterales	28221|Deltaproteobacteria	S	metal-dependent phosphohydrolase 7TM intracellular region	-	-	-	ko:K07037	-	-	-	-	ko00000	-	-	-	7TM-7TMR_HD,7TMR-HDED,HD
k59_10867_1	96561.Dole_2296	4.86e-83	254.0	COG3264@1|root,COG3264@2|Bacteria,1QUBW@1224|Proteobacteria,43BRN@68525|delta/epsilon subdivisions,2X72H@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Mechanosensitive ion channel	-	-	-	ko:K03442	-	-	-	-	ko00000,ko02000	1.A.23.2	-	-	MS_channel,TM_helix
k59_215321_1	643562.Daes_0373	4.94e-44	165.0	COG2199@1|root,COG3852@1|root,COG5001@1|root,COG3706@2|Bacteria,COG3852@2|Bacteria,COG5001@2|Bacteria,1MZV7@1224|Proteobacteria,42S7S@68525|delta/epsilon subdivisions,2WNFR@28221|Deltaproteobacteria,2M9XW@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GGDEF,PAS,PAS_3,PAS_4
k59_192668_1	1232410.KI421413_gene960	3.69e-24	107.0	COG0760@1|root,COG0760@2|Bacteria,1MWV0@1224|Proteobacteria,42MPK@68525|delta/epsilon subdivisions,2WJM1@28221|Deltaproteobacteria,43RYI@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	SurA N-terminal domain	nifM	-	5.2.1.8	ko:K03770	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N_3
k59_86402_1	1437824.BN940_02131	1.84e-53	183.0	COG1686@1|root,COG1686@2|Bacteria,1MUU7@1224|Proteobacteria,2VH46@28216|Betaproteobacteria,3T1UE@506|Alcaligenaceae	28216|Betaproteobacteria	M	Belongs to the peptidase S11 family	dacC	-	3.4.16.4	ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	PBP5_C,Peptidase_S11
k59_238254_1	879212.DespoDRAFT_02349	7.7e-29	109.0	COG0250@1|root,COG0250@2|Bacteria,1QTE5@1224|Proteobacteria,42QT0@68525|delta/epsilon subdivisions,2WN4B@28221|Deltaproteobacteria,2MJNB@213118|Desulfobacterales	28221|Deltaproteobacteria	K	Transcription termination factor nusG	-	-	-	ko:K05785	-	-	-	-	ko00000,ko03000	-	-	-	NusG
k59_25839_1	933262.AXAM01000057_gene1535	2.42e-103	310.0	COG1183@1|root,COG1183@2|Bacteria,1MWD9@1224|Proteobacteria,42QV4@68525|delta/epsilon subdivisions,2WMR6@28221|Deltaproteobacteria,2MJGV@213118|Desulfobacterales	28221|Deltaproteobacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pssA	-	2.7.8.8	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	M00093	R01800	RC00002,RC00017,RC02795	ko00000,ko00001,ko00002,ko01000	-	-	-	CDP-OH_P_transf
k59_230776_2	243159.AFE_2678	0.000917	40.8	COG0297@1|root,COG0297@2|Bacteria,1MUGM@1224|Proteobacteria,1RNMP@1236|Gammaproteobacteria,2NCD0@225057|Acidithiobacillales	225057|Acidithiobacillales	G	Synthesizes alpha-1,4-glucan chains using ADP-glucose	glgA	-	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Glyco_transf_5,Glycos_transf_1
k59_10871_1	439235.Dalk_2373	5.52e-82	256.0	COG0426@1|root,COG0426@2|Bacteria,1R4UD@1224|Proteobacteria,43AF5@68525|delta/epsilon subdivisions,2X5UW@28221|Deltaproteobacteria,2MPG5@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Flavodoxin	roo	-	-	-	-	-	-	-	-	-	-	-	Flavodoxin_1,Lactamase_B,Lactamase_B_2
k59_94142_1	1123355.JHYO01000025_gene2126	2.23e-20	89.0	COG1763@1|root,COG1763@2|Bacteria,1RD3Q@1224|Proteobacteria,2U5T0@28211|Alphaproteobacteria,370HD@31993|Methylocystaceae	28211|Alphaproteobacteria	H	Molybdopterin guanine dinucleotide synthesis protein B	mobB	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0005488,GO:0005525,GO:0017076,GO:0019001,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	ko:K03753	-	-	-	-	ko00000	-	-	-	MobB
k59_94142_2	111781.Lepto7376_3044	9.4e-36	130.0	COG1489@1|root,COG1489@2|Bacteria,1G1PM@1117|Cyanobacteria,1HA1K@1150|Oscillatoriales	1117|Cyanobacteria	S	Belongs to the SfsA family	sfsA	-	-	ko:K06206	-	-	-	-	ko00000	-	-	-	SfsA
k59_162437_1	479434.Sthe_3388	8.96e-126	389.0	COG0243@1|root,COG3383@1|root,COG0243@2|Bacteria,COG3383@2|Bacteria,2G62W@200795|Chloroflexi,27YXY@189775|Thermomicrobia	189775|Thermomicrobia	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Molybdopterin,Molydop_binding
k59_71338_1	768671.ThimaDRAFT_0873	2.07e-83	263.0	COG3653@1|root,COG3653@2|Bacteria,1MWWY@1224|Proteobacteria,1TFGB@1236|Gammaproteobacteria,1X1MI@135613|Chromatiales	135613|Chromatiales	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
k59_102008_2	742767.HMPREF9456_00608	0.0002	48.1	COG1538@1|root,COG1538@2|Bacteria,4NF4V@976|Bacteroidetes,2FM0S@200643|Bacteroidia,22WY2@171551|Porphyromonadaceae	976|Bacteroidetes	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
k59_200343_1	767817.Desgi_4277	2.61e-140	428.0	COG0745@1|root,COG5002@1|root,COG0745@2|Bacteria,COG5002@2|Bacteria,1VRP7@1239|Firmicutes,24YHW@186801|Clostridia	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,Hpt,PAS_9,Response_reg
k59_238256_1	641491.DND132_2395	4.4e-25	108.0	COG2414@1|root,COG2414@2|Bacteria,1MWBB@1224|Proteobacteria,42NR7@68525|delta/epsilon subdivisions,2WK49@28221|Deltaproteobacteria,2MAH4@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	PFAM Aldehyde ferredoxin oxidoreductase	-	-	1.2.7.5	ko:K03738	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00309	R08571	RC00242	ko00000,ko00001,ko00002,ko01000	-	-	-	AFOR_C,AFOR_N
k59_200345_1	56780.SYN_00309	1.1e-90	280.0	COG0064@1|root,COG0064@2|Bacteria,1MUKG@1224|Proteobacteria,42M31@68525|delta/epsilon subdivisions,2WJK4@28221|Deltaproteobacteria,2MQ8D@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
k59_116718_1	56780.SYN_00591	1.14e-87	263.0	COG1225@1|root,COG1225@2|Bacteria,1N9JS@1224|Proteobacteria,42R82@68525|delta/epsilon subdivisions,2WMVA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	1.11.1.15	ko:K03386	ko04214,map04214	-	-	-	ko00000,ko00001,ko01000,ko04147	-	-	-	AhpC-TSA
k59_177518_1	1121405.dsmv_0661	4.59e-59	190.0	COG0517@1|root,COG0517@2|Bacteria,1PDG6@1224|Proteobacteria,42QQ0@68525|delta/epsilon subdivisions,2WMQ6@28221|Deltaproteobacteria,2MKN2@213118|Desulfobacterales	28221|Deltaproteobacteria	S	PFAM CBS domain	-	-	-	ko:K04767	-	-	-	-	ko00000	-	-	-	CBS
k59_41071_1	1121405.dsmv_1522	9.1e-67	218.0	COG2271@1|root,COG2271@2|Bacteria,1PND6@1224|Proteobacteria,42QTW@68525|delta/epsilon subdivisions,2WMNU@28221|Deltaproteobacteria,2MJYF@213118|Desulfobacterales	28221|Deltaproteobacteria	G	Major Facilitator Superfamily	-	-	-	ko:K02445	-	-	-	-	ko00000,ko02000	2.A.1.4.3	-	-	MFS_1
k59_124898_2	1121439.dsat_2791	1.17e-47	160.0	COG1291@1|root,COG1291@2|Bacteria,1MXK3@1224|Proteobacteria,42PR1@68525|delta/epsilon subdivisions,2WIQ8@28221|Deltaproteobacteria,2M7ZH@213115|Desulfovibrionales	28221|Deltaproteobacteria	N	PFAM MotA TolQ ExbB proton channel	motA	-	-	ko:K02556	ko02020,ko02030,ko02040,map02020,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	MotA_ExbB
k59_139851_1	1454004.AW11_02535	2.79e-101	315.0	COG2358@1|root,COG2358@2|Bacteria,1PNJV@1224|Proteobacteria,2VI8H@28216|Betaproteobacteria,1KQBK@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	S	NMT1-like family	-	-	-	-	-	-	-	-	-	-	-	-	NMT1_3
k59_10894_1	1121405.dsmv_0340	1.74e-107	324.0	COG0260@1|root,COG0260@2|Bacteria,1MUF9@1224|Proteobacteria,42M2G@68525|delta/epsilon subdivisions,2WJ80@28221|Deltaproteobacteria,2MIFW@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides	pepA	-	3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17,Peptidase_M17_N
k59_10895_1	1265505.ATUG01000001_gene3684	4.73e-44	166.0	COG4191@1|root,COG4564@1|root,COG4191@2|Bacteria,COG4564@2|Bacteria,1RCM9@1224|Proteobacteria,43BKN@68525|delta/epsilon subdivisions,2X7PG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4,PAS_9,Response_reg
k59_71366_1	1121405.dsmv_2328	1.12e-80	250.0	COG4972@1|root,COG4972@2|Bacteria,1MX8P@1224|Proteobacteria,42M36@68525|delta/epsilon subdivisions,2WJFJ@28221|Deltaproteobacteria,2MID0@213118|Desulfobacterales	28221|Deltaproteobacteria	NU	TIGRFAM type IV pilus assembly protein PilM	pilM	-	-	ko:K02662	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilM_2
k59_102029_1	163908.KB235896_gene4419	1.42e-36	136.0	COG1215@1|root,COG1215@2|Bacteria,1G5XD@1117|Cyanobacteria,1HTSA@1161|Nostocales	1117|Cyanobacteria	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
k59_132163_1	1121406.JAEX01000003_gene1497	7.14e-79	243.0	COG0410@1|root,COG0410@2|Bacteria,1MVVC@1224|Proteobacteria,42M5A@68525|delta/epsilon subdivisions,2WK03@28221|Deltaproteobacteria,2M9W9@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	PFAM ABC transporter related	livF	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
k59_94169_1	1121405.dsmv_3255	1.99e-24	102.0	COG0465@1|root,COG0465@2|Bacteria,1MU6J@1224|Proteobacteria,42M4Z@68525|delta/epsilon subdivisions,2WJ0D@28221|Deltaproteobacteria,2MIPH@213118|Desulfobacterales	28221|Deltaproteobacteria	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
k59_162454_1	335543.Sfum_0614	5.11e-105	311.0	COG0388@1|root,COG0388@2|Bacteria	2|Bacteria	S	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	-	-	-	-	-	-	-	-	-	-	-	-	CN_hydrolase
k59_169958_7	760732.E5E454_9CAUD	6.01e-33	122.0	4QAZ8@10239|Viruses,4R074@35237|dsDNA viruses  no RNA stage,4QQTR@28883|Caudovirales,4QJ63@10662|Myoviridae	10662|Myoviridae	S	DNA mediated transformation	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_169958_11	1045856.EcWSU1_02345	3.49e-08	59.7	COG0270@1|root,COG0270@2|Bacteria,1MV9H@1224|Proteobacteria,1RPSH@1236|Gammaproteobacteria,3X3FF@547|Enterobacter	1236|Gammaproteobacteria	H	C-5 cytosine-specific DNA methylase	-	-	2.1.1.37	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	M00035	R04858	RC00003,RC00332	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_methylase,Dam,MethyltransfD12
k59_41077_1	472759.Nhal_0237	2.22e-156	450.0	COG3385@1|root,COG3385@2|Bacteria,1PMXF@1224|Proteobacteria,1RMHK@1236|Gammaproteobacteria,1X1NE@135613|Chromatiales	135613|Chromatiales	L	transposase IS4	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DUF4372
k59_139864_1	439235.Dalk_1318	2.63e-65	202.0	COG1943@1|root,COG1943@2|Bacteria,1MX19@1224|Proteobacteria,43BHF@68525|delta/epsilon subdivisions,2WQUJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	PFAM Transposase IS200 like	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
k59_208195_1	384765.SIAM614_02246	1.31e-14	79.3	COG1835@1|root,COG1835@2|Bacteria,1MV2W@1224|Proteobacteria,2TRT8@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	Acyl-transferase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
k59_86436_1	768672.Desfe_1077	1.07e-42	152.0	COG0624@1|root,arCOG01107@2157|Archaea,2XPT0@28889|Crenarchaeota	28889|Crenarchaeota	E	TIGRFAM acetylornithine deacetylase or succinyl-diaminopimelate desuccinylase	-	-	3.5.1.18	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R02734	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
k59_33553_1	335543.Sfum_0610	1.42e-67	228.0	COG0243@1|root,COG0243@2|Bacteria,1R4RR@1224|Proteobacteria,42PA5@68525|delta/epsilon subdivisions,2WM0K@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	qrcB	-	-	ko:K08357	ko00920,ko01120,ko02020,map00920,map01120,map02020	-	R10150	RC03109	ko00000,ko00001,ko02000	5.A.3.10	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
k59_33553_2	941449.dsx2_3078	1.77e-54	178.0	COG3474@1|root,COG3474@2|Bacteria,1QUNA@1224|Proteobacteria,42PVG@68525|delta/epsilon subdivisions,2WJ7N@28221|Deltaproteobacteria,2M95U@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	PFAM cytochrome c class III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_CIII,Cytochrome_C7
k59_56463_1	1121456.ATVA01000014_gene756	0.000484	47.0	COG0457@1|root,COG3147@1|root,COG0457@2|Bacteria,COG3147@2|Bacteria,1PDTX@1224|Proteobacteria,42RK5@68525|delta/epsilon subdivisions,2WNZC@28221|Deltaproteobacteria,2M93P@213115|Desulfovibrionales	28221|Deltaproteobacteria	D	repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	SPOR,TPR_1,TPR_11,TPR_16,TPR_19,TPR_2,TPR_8
k59_124917_1	1089553.Tph_c03400	5.21e-40	150.0	COG1239@1|root,COG1240@1|root,COG1239@2|Bacteria,COG1240@2|Bacteria,1UHYK@1239|Firmicutes,24BJ0@186801|Clostridia,42FRU@68295|Thermoanaerobacterales	186801|Clostridia	H	von Willebrand factor (vWF) type A domain	-	-	6.6.1.1	ko:K03404,ko:K03405	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R03877	RC01012	ko00000,ko00001,ko01000	-	-	-	AAA_5,Mg_chelatase,VWA_2
k59_197758_1	643562.Daes_0559	4.86e-47	172.0	COG2208@1|root,COG2972@1|root,COG2208@2|Bacteria,COG2972@2|Bacteria,1QUX7@1224|Proteobacteria,42ZQY@68525|delta/epsilon subdivisions,2WUWY@28221|Deltaproteobacteria,2MGWA@213115|Desulfovibrionales	28221|Deltaproteobacteria	KT	histidine kinase HAMP region domain protein	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	HAMP,HATPase_c_2,SpoIIE
k59_190101_1	439235.Dalk_2557	3.49e-63	216.0	COG3383@1|root,COG3383@2|Bacteria,1QTZB@1224|Proteobacteria,42SPZ@68525|delta/epsilon subdivisions,2WIV9@28221|Deltaproteobacteria,2MIGI@213118|Desulfobacterales	68525|delta/epsilon subdivisions	C	PFAM molybdopterin oxidoreductase	nuoG-1	-	1.17.1.10,1.6.5.3	ko:K00336,ko:K05299	ko00190,ko00680,ko00720,ko01100,ko01120,ko01200,map00190,map00680,map00720,map01100,map01120,map01200	M00144,M00377	R00134,R11945	RC00061,RC02796	ko00000,ko00001,ko00002,ko01000	3.D.1	-	iAF987.Gmet_3349	Fer2_4,Fer4,Fer4_10,Fer4_7,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
k59_227965_1	880072.Desac_2383	2.18e-18	86.7	COG1226@1|root,32Y28@2|Bacteria,1PVKD@1224|Proteobacteria,4379F@68525|delta/epsilon subdivisions,2X2D3@28221|Deltaproteobacteria,2MSI0@213462|Syntrophobacterales	28221|Deltaproteobacteria	P	Ion transport 2 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Ion_trans_2
k59_144639_1	1121468.AUBR01000019_gene2662	6.2e-62	206.0	COG0407@1|root,COG0407@2|Bacteria,1TRJG@1239|Firmicutes,24B34@186801|Clostridia,42G9W@68295|Thermoanaerobacterales	186801|Clostridia	H	Evidence 4 Homologs of previously reported genes of	-	-	-	-	-	-	-	-	-	-	-	-	URO-D
k59_152251_1	27923.ML063336a-PA	7.22e-28	116.0	COG0349@1|root,KOG2206@2759|Eukaryota,38D24@33154|Opisthokonta,3BK12@33208|Metazoa	33208|Metazoa	J	exosome component 10	EXOSC10	GO:0000175,GO:0000176,GO:0000178,GO:0000278,GO:0000460,GO:0000737,GO:0000785,GO:0000956,GO:0002252,GO:0002376,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005652,GO:0005654,GO:0005694,GO:0005730,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006308,GO:0006309,GO:0006364,GO:0006378,GO:0006396,GO:0006397,GO:0006401,GO:0006402,GO:0006403,GO:0006725,GO:0006807,GO:0006810,GO:0006897,GO:0006909,GO:0006915,GO:0006921,GO:0006950,GO:0006952,GO:0007049,GO:0007059,GO:0007275,GO:0007549,GO:0008150,GO:0008152,GO:0008219,GO:0008298,GO:0008334,GO:0008408,GO:0009048,GO:0009056,GO:0009057,GO:0009605,GO:0009607,GO:0009615,GO:0009790,GO:0009792,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0010639,GO:0012501,GO:0016043,GO:0016070,GO:0016071,GO:0016072,GO:0016075,GO:0016192,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0019219,GO:0019222,GO:0019439,GO:0022411,GO:0022613,GO:0030262,GO:0031123,GO:0031124,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031974,GO:0031981,GO:0032204,GO:0032205,GO:0032210,GO:0032211,GO:0032501,GO:0032502,GO:0032879,GO:0032991,GO:0033036,GO:0033043,GO:0033044,GO:0034399,GO:0034470,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0035327,GO:0040029,GO:0042254,GO:0043170,GO:0043207,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043277,GO:0043631,GO:0043632,GO:0043633,GO:0043634,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044444,GO:0044446,GO:0044464,GO:0045934,GO:0046483,GO:0046700,GO:0048519,GO:0048523,GO:0048856,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051053,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051179,GO:0051234,GO:0051607,GO:0051641,GO:0051704,GO:0051707,GO:0060255,GO:0065007,GO:0065008,GO:0070013,GO:0070034,GO:0070727,GO:0071025,GO:0071027,GO:0071028,GO:0071029,GO:0071030,GO:0071033,GO:0071034,GO:0071035,GO:0071043,GO:0071044,GO:0071046,GO:0071048,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:0097194,GO:0098542,GO:0098657,GO:0140098,GO:1901360,GO:1901361,GO:1901363,GO:1901575,GO:1902494,GO:1904356,GO:1904357,GO:1904872,GO:1905354,GO:2000112,GO:2000113,GO:2000278,GO:2000279,GO:2001251	-	ko:K12591	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DNA_pol_A_exo1,HRDC,PMC2NT
k59_152257_1	1125863.JAFN01000001_gene39	3.59e-31	118.0	COG0332@1|root,COG0332@2|Bacteria,1MU9N@1224|Proteobacteria,42MU6@68525|delta/epsilon subdivisions,2WIJN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH-2	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
k59_152257_2	177437.HRM2_36670	1.28e-61	202.0	COG0569@1|root,COG0569@2|Bacteria,1MW8R@1224|Proteobacteria,42NWZ@68525|delta/epsilon subdivisions,2WJU7@28221|Deltaproteobacteria,2MJ2C@213118|Desulfobacterales	28221|Deltaproteobacteria	P	PFAM TrkA-N domain	trkA	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
k59_175046_1	1541960.KQ78_01293	4.94e-26	107.0	COG3299@1|root,COG3497@1|root,COG3299@2|Bacteria,COG3497@2|Bacteria	2|Bacteria	S	Phage tail sheath protein subtilisin-like domain	-	-	3.2.1.78	ko:K01218,ko:K06907	ko00051,ko02024,map00051,map02024	-	R01332	RC00467	ko00000,ko00001,ko01000	-	GH26	-	Baseplate_J,PA14,Phage_sheath_1,Phage_sheath_1C,fn3
k59_8214_1	330214.NIDE0660	6.45e-47	165.0	COG1373@1|root,COG1373@2|Bacteria,3J14P@40117|Nitrospirae	40117|Nitrospirae	S	AAA domain	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
k59_121946_1	335543.Sfum_0561	1.3e-78	253.0	COG0018@1|root,COG0018@2|Bacteria,1MU4J@1224|Proteobacteria,42MTY@68525|delta/epsilon subdivisions,2WKII@28221|Deltaproteobacteria,2MQ9N@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	TIGRFAM Arginyl-tRNA synthetase	argS	GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	iAF987.Gmet_1434	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
k59_220616_3	794903.OPIT5_03930	1.22e-53	181.0	COG0175@1|root,COG0175@2|Bacteria	2|Bacteria	EH	sulfate reduction	-	-	1.8.4.10,1.8.4.8	ko:K00390	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00176	R02021	RC00007,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	-	PAPS_reduct
k59_159928_1	903818.KI912268_gene3428	2.15e-12	72.4	COG4584@1|root,COG4584@2|Bacteria,3Y6WU@57723|Acidobacteria	57723|Acidobacteria	L	PFAM Integrase catalytic	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_8217_1	941449.dsx2_1445	4.39e-133	387.0	COG3049@1|root,COG3049@2|Bacteria,1MWPQ@1224|Proteobacteria,42QQ7@68525|delta/epsilon subdivisions,2WN8Z@28221|Deltaproteobacteria,2M8UD@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Linear amide C-N hydrolases, choloylglycine hydrolase family	-	-	3.5.1.24	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	-	R02797,R03975,R03977,R04486,R04487,R05835	RC00090,RC00096	ko00000,ko00001,ko01000	-	-	-	CBAH
k59_15769_1	1121405.dsmv_0302	1.23e-120	360.0	COG1508@1|root,COG1508@2|Bacteria,1MW4V@1224|Proteobacteria,42M3C@68525|delta/epsilon subdivisions,2WJ21@28221|Deltaproteobacteria,2MHTM@213118|Desulfobacterales	28221|Deltaproteobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	rpoN	-	-	ko:K03092	ko02020,ko05111,map02020,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma54_AID,Sigma54_CBD,Sigma54_DBD
k59_114263_1	477974.Daud_0493	7.66e-18	79.0	COG1661@1|root,COG1661@2|Bacteria,1VFBA@1239|Firmicutes,24QM1@186801|Clostridia,265QB@186807|Peptococcaceae	186801|Clostridia	S	Domain of unknown function (DUF296)	-	-	-	-	-	-	-	-	-	-	-	-	DUF296
k59_182543_1	1304885.AUEY01000001_gene3187	7.69e-50	164.0	COG2181@1|root,COG2181@2|Bacteria,1RADK@1224|Proteobacteria,42RA7@68525|delta/epsilon subdivisions,2WMPI@28221|Deltaproteobacteria,2MJKM@213118|Desulfobacterales	28221|Deltaproteobacteria	C	nitrate reductase activity	hmcE	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Nitrate_red_gam
k59_46104_1	1167006.UWK_00950	2.79e-08	56.2	COG0835@1|root,COG0835@2|Bacteria,1RAH1@1224|Proteobacteria,42TH2@68525|delta/epsilon subdivisions,2WQPG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	NT	Two component signalling adaptor domain	-	-	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
k59_46104_2	1121403.AUCV01000025_gene2298	4.47e-14	77.8	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42R36@68525|delta/epsilon subdivisions,2WU0Z@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	frzCD	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal,PAS_4,PAS_9,dCache_1,sCache_3_2,sCache_3_3
k59_61470_2	933262.AXAM01000061_gene1669	3.59e-19	89.0	COG4966@1|root,COG4966@2|Bacteria,1N2NR@1224|Proteobacteria,42TRJ@68525|delta/epsilon subdivisions,2WQQ2@28221|Deltaproteobacteria,2MKHU@213118|Desulfobacterales	28221|Deltaproteobacteria	NU	pilus assembly protein PilW	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,PilW
k59_99137_1	1121127.JAFA01000043_gene4191	1.28e-26	108.0	COG2995@1|root,COG2995@2|Bacteria,1MWG1@1224|Proteobacteria,2VMXT@28216|Betaproteobacteria,1K33I@119060|Burkholderiaceae	28216|Betaproteobacteria	S	paraquat-inducible protein A	pqiA	-	-	ko:K03808	-	-	-	-	ko00000	-	-	-	PqiA
k59_99137_2	933262.AXAM01000106_gene2631	1.86e-16	79.7	COG2995@1|root,COG2995@2|Bacteria,1MWG1@1224|Proteobacteria,42R11@68525|delta/epsilon subdivisions,2WMWN@28221|Deltaproteobacteria,2MMZB@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Paraquat-inducible protein A	-	-	-	ko:K03808	-	-	-	-	ko00000	-	-	-	PqiA
k59_76479_3	10761.Q716H0_BPSFV	2.53e-21	93.6	4QBD3@10239|Viruses,4QXFU@35237|dsDNA viruses  no RNA stage,4QQ7Z@28883|Caudovirales,4QNJ0@10744|Podoviridae	10744|Podoviridae	S	P22 coat protein - gene protein 5	-	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0008150,GO:0009987,GO:0016032,GO:0016043,GO:0019012,GO:0019028,GO:0019030,GO:0019058,GO:0019068,GO:0019069,GO:0019075,GO:0022607,GO:0039620,GO:0042802,GO:0042803,GO:0044085,GO:0044403,GO:0044419,GO:0044423,GO:0046729,GO:0046797,GO:0046983,GO:0051704,GO:0071840	-	-	-	-	-	-	-	-	-	-	-
k59_167338_1	211165.AJLN01000113_gene5972	1.94e-83	263.0	COG1228@1|root,COG1228@2|Bacteria,1G3PN@1117|Cyanobacteria,1JJVV@1189|Stigonemataceae	1117|Cyanobacteria	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
k59_15777_1	335543.Sfum_0717	3.06e-80	247.0	COG1032@1|root,COG1032@2|Bacteria,1P9J0@1224|Proteobacteria,42MWG@68525|delta/epsilon subdivisions,2WIV5@28221|Deltaproteobacteria,2MQYP@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
k59_190129_1	1232410.KI421421_gene3812	2.84e-15	76.6	COG0330@1|root,COG0330@2|Bacteria,1MV7R@1224|Proteobacteria,42N2V@68525|delta/epsilon subdivisions,2WIPS@28221|Deltaproteobacteria,43TMP@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	prohibitin homologues	hflC	-	-	ko:K04087	-	M00742	-	-	ko00000,ko00002,ko01000	-	-	-	Band_7
k59_129503_1	933262.AXAM01000057_gene1536	1.04e-97	293.0	COG0473@1|root,COG0473@2|Bacteria,1MUH4@1224|Proteobacteria,42M8G@68525|delta/epsilon subdivisions,2WIYB@28221|Deltaproteobacteria,2MIG1@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate	leuB	-	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
k59_83995_1	1280954.HPO_12608	0.000126	48.1	COG2091@1|root,COG2091@2|Bacteria,1MZHC@1224|Proteobacteria,2UFA4@28211|Alphaproteobacteria	28211|Alphaproteobacteria	H	Belongs to the P-Pant transferase superfamily	-	-	-	ko:K06133	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	-	ACPS
k59_83995_2	1265505.ATUG01000001_gene2919	1.69e-34	129.0	COG0443@1|root,COG0443@2|Bacteria,1P7BK@1224|Proteobacteria,42PNW@68525|delta/epsilon subdivisions,2WKSX@28221|Deltaproteobacteria,2MHUK@213118|Desulfobacterales	28221|Deltaproteobacteria	O	PRTRC system protein D	-	-	-	ko:K18640	-	-	-	-	ko00000,ko04812	-	-	-	-
k59_144664_1	504472.Slin_2662	2.41e-67	215.0	COG2801@1|root,COG2963@1|root,COG2801@2|Bacteria,COG2963@2|Bacteria,4NJ32@976|Bacteroidetes,47TE9@768503|Cytophagia	976|Bacteroidetes	L	PFAM Integrase catalytic region	-	-	-	-	-	-	-	-	-	-	-	-	HTH_32,rve,rve_3
k59_212832_1	1236976.JCM16418_3174	1.02e-14	77.0	COG0382@1|root,COG0382@2|Bacteria,1TQU5@1239|Firmicutes,4HAGP@91061|Bacilli,26R65@186822|Paenibacillaceae	91061|Bacilli	H	4-hydroxybenzoate polyprenyltransferase	ubiA	-	2.5.1.39	ko:K03179	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R05000,R05615	RC00209,RC02895	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
k59_190141_1	1167006.UWK_00817	2.82e-67	228.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2WJN5@28221|Deltaproteobacteria,2MMWB@213118|Desulfobacterales	28221|Deltaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_15792_1	637905.SVI_1747	1.66e-47	170.0	COG2267@1|root,COG2267@2|Bacteria,1QTZP@1224|Proteobacteria,1RPB9@1236|Gammaproteobacteria,2Q93K@267890|Shewanellaceae	1236|Gammaproteobacteria	I	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6,Hydrolase_4
k59_15792_2	765911.Thivi_0537	1.26e-20	90.1	COG4782@1|root,COG4782@2|Bacteria,1MVAD@1224|Proteobacteria,1S13M@1236|Gammaproteobacteria,1WWSG@135613|Chromatiales	135613|Chromatiales	S	PFAM Alpha beta hydrolase of	-	-	-	-	-	-	-	-	-	-	-	-	DUF900
k59_61483_1	1500897.JQNA01000002_gene4620	2.76e-21	95.9	COG3437@1|root,COG4585@1|root,COG3437@2|Bacteria,COG4585@2|Bacteria,1RGET@1224|Proteobacteria,2VPRS@28216|Betaproteobacteria,1KHSR@119060|Burkholderiaceae	28216|Betaproteobacteria	T	Multi-sensor signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA_3,PAS,PAS_4,PAS_9,Reg_prop,Response_reg,Y_Y_Y
k59_61483_2	177437.HRM2_34570	4.99e-28	112.0	COG0477@1|root,COG2814@2|Bacteria,1R9V9@1224|Proteobacteria,42Q1C@68525|delta/epsilon subdivisions,2WK7P@28221|Deltaproteobacteria,2MMQA@213118|Desulfobacterales	28221|Deltaproteobacteria	EGP	Major Facilitator Superfamily	-	-	-	ko:K02575	ko00910,map00910	M00615	-	-	ko00000,ko00001,ko00002,ko02000	2.A.1.8	-	-	MFS_1
k59_23429_1	439235.Dalk_4508	3.97e-34	134.0	COG1295@1|root,COG1295@2|Bacteria,1QICW@1224|Proteobacteria,42MBW@68525|delta/epsilon subdivisions,2WK2Z@28221|Deltaproteobacteria,2MIKX@213118|Desulfobacterales	28221|Deltaproteobacteria	K	ribonuclease BN	-	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Rrf2,Virul_fac_BrkB
k59_106811_1	610130.Closa_1217	5.63e-05	48.5	COG2844@1|root,COG2844@2|Bacteria,1V2GH@1239|Firmicutes,24FRR@186801|Clostridia,220NU@1506553|Lachnoclostridium	186801|Clostridia	O	PFAM metal-dependent phosphohydrolase HD sub domain	-	-	-	-	-	-	-	-	-	-	-	-	HD
k59_68932_1	1548903.A0A0A1IUT4_9CAUD	3.76e-29	119.0	4QF04@10239|Viruses,4QPIK@28883|Caudovirales,4QIGQ@10662|Myoviridae	10662|Myoviridae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_228012_1	983544.Lacal_2910	4.32e-76	235.0	COG2801@1|root,COG2801@2|Bacteria,4NM64@976|Bacteroidetes,1HZ28@117743|Flavobacteriia	976|Bacteroidetes	L	COG2801 Transposase and inactivated derivatives	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	rve,rve_3
k59_23439_1	1121405.dsmv_2539	6.52e-97	301.0	COG3276@1|root,COG3276@2|Bacteria,1MWXH@1224|Proteobacteria,42M49@68525|delta/epsilon subdivisions,2WJ5G@28221|Deltaproteobacteria,2MIIX@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Elongation factor SelB winged helix	selB	-	-	ko:K03833	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,SelB-wing_2,SelB-wing_3
k59_190557_1	7668.SPU_009575-tr	2.52e-84	279.0	COG2801@1|root,KOG0017@2759|Eukaryota,39Z2B@33154|Opisthokonta,3BIIP@33208|Metazoa,3D489@33213|Bilateria	33208|Metazoa	L	SCAN domain	-	-	-	-	-	-	-	-	-	-	-	-	RVT_1,SCAN,rve
k59_61917_1	1125863.JAFN01000001_gene2796	2.3e-24	107.0	COG0493@1|root,COG0493@2|Bacteria,1MU2H@1224|Proteobacteria,42PJ7@68525|delta/epsilon subdivisions,2WMEM@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_20,Fer4_7,Pyr_redox_2
k59_61917_2	1265505.ATUG01000001_gene4572	4.27e-12	66.2	COG0633@1|root,COG3894@1|root,COG0633@2|Bacteria,COG3894@2|Bacteria,1MV6C@1224|Proteobacteria,42MF5@68525|delta/epsilon subdivisions,2WKC6@28221|Deltaproteobacteria,2MI4B@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Domain of unknown function (DUF4445)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4445,Fer2
k59_114772_1	693661.Arcve_1009	2.4e-58	196.0	COG0683@1|root,arCOG01020@2157|Archaea,2Y3WF@28890|Euryarchaeota	28890|Euryarchaeota	E	Periplasmic binding protein	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
k59_114772_2	644282.Deba_1014	2.06e-123	363.0	COG4177@1|root,COG4177@2|Bacteria,1MV66@1224|Proteobacteria,42MTH@68525|delta/epsilon subdivisions,2WJQY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	PFAM Branched-chain amino acid transport system permease component	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
k59_228477_1	96561.Dole_2686	1.57e-65	221.0	COG0515@1|root,COG0515@2|Bacteria,1N9V2@1224|Proteobacteria,42Q0B@68525|delta/epsilon subdivisions,2WJXJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	KLT	type IV pilus assembly PilZ	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_99638_1	1408422.JHYF01000002_gene2527	7.66e-06	53.5	COG1589@1|root,COG1589@2|Bacteria,1VEMW@1239|Firmicutes,24QKM@186801|Clostridia	186801|Clostridia	D	Cell division protein FtsQ	ftsQ	-	-	ko:K03589	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036	-	-	-	FtsQ,POTRA_1
k59_8655_1	1121405.dsmv_0564	1.94e-59	206.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1MXBU@1224|Proteobacteria,42M59@68525|delta/epsilon subdivisions,2WIUK@28221|Deltaproteobacteria,2MICN@213118|Desulfobacterales	28221|Deltaproteobacteria	G	Pyruvate phosphate dikinase, PEP	-	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PPDK_N
k59_54153_1	1504672.669787359	2.08e-54	181.0	COG2826@1|root,COG2826@2|Bacteria,1MWI0@1224|Proteobacteria,2VSAV@28216|Betaproteobacteria,4AJAN@80864|Comamonadaceae	28216|Betaproteobacteria	L	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_38,rve
k59_23889_1	880072.Desac_0138	4.27e-41	145.0	COG0002@1|root,COG0002@2|Bacteria,1MVJ6@1224|Proteobacteria,42MDN@68525|delta/epsilon subdivisions,2WINX@28221|Deltaproteobacteria,2MQBD@213462|Syntrophobacterales	28221|Deltaproteobacteria	E	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde	argC	-	1.2.1.38	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R03443	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
k59_23889_2	335543.Sfum_1666	2.2e-69	220.0	COG0101@1|root,COG0101@2|Bacteria,1MUYI@1224|Proteobacteria,42RTC@68525|delta/epsilon subdivisions,2WNQ6@28221|Deltaproteobacteria,2MQGR@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
k59_54158_1	1121405.dsmv_1568	2.33e-26	105.0	COG1418@1|root,COG1418@2|Bacteria,1R60M@1224|Proteobacteria,42NFJ@68525|delta/epsilon subdivisions,2WIJT@28221|Deltaproteobacteria,2MJ3J@213118|Desulfobacterales	28221|Deltaproteobacteria	S	PFAM metal-dependent phosphohydrolase HD sub	-	-	-	-	-	-	-	-	-	-	-	-	HD
k59_77088_1	985665.HPL003_13960	2.1e-22	99.8	COG0489@1|root,COG0489@2|Bacteria,1TS4R@1239|Firmicutes,4HCEN@91061|Bacilli,26TAD@186822|Paenibacillaceae	91061|Bacilli	D	capsular	yveL	-	-	-	-	-	-	-	-	-	-	-	AAA_31
k59_8664_1	879212.DespoDRAFT_00152	5.05e-30	110.0	COG2109@1|root,COG2109@2|Bacteria,1MUN6@1224|Proteobacteria,42RPD@68525|delta/epsilon subdivisions,2WNI0@28221|Deltaproteobacteria,2MK1B@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids	-	-	2.5.1.17	ko:K19221	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	CobA_CobO_BtuR
k59_99646_1	1201288.M900_0557	5.06e-59	206.0	COG0643@1|root,COG0643@2|Bacteria,1MUAG@1224|Proteobacteria,42M6Q@68525|delta/epsilon subdivisions,2WJ5U@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Signal transducing histidine kinase homodimeric	-	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt,Response_reg
k59_160451_1	335543.Sfum_1695	7.93e-84	258.0	COG2805@1|root,COG2805@2|Bacteria,1MU3J@1224|Proteobacteria,42M7F@68525|delta/epsilon subdivisions,2WIMF@28221|Deltaproteobacteria,2MQ3Y@213462|Syntrophobacterales	28221|Deltaproteobacteria	NU	PFAM Type II IV secretion system protein	-	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
k59_145141_1	933262.AXAM01000013_gene1310	7.21e-190	559.0	COG1026@1|root,COG1026@2|Bacteria,1MVDJ@1224|Proteobacteria,42MRG@68525|delta/epsilon subdivisions,2WJ5Q@28221|Deltaproteobacteria,2MINB@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Peptidase M16C associated	PREP	-	-	ko:K06972	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M16C_assoc,Peptidase_M16,Peptidase_M16_C
k59_205884_1	391587.KAOT1_04280	8.75e-29	116.0	COG1033@1|root,COG1033@2|Bacteria,4NKHV@976|Bacteroidetes,1HZPQ@117743|Flavobacteriia	976|Bacteroidetes	S	Patched family	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
k59_183065_1	1157943.KB892705_gene2039	4.34e-62	204.0	COG3969@1|root,COG3969@2|Bacteria,2H4MT@201174|Actinobacteria	201174|Actinobacteria	S	Phosphoadenosine phosphosulfate reductase family	-	-	-	-	-	-	-	-	-	-	-	-	PAPS_reduct
k59_122438_1	398767.Glov_3047	2.49e-13	68.6	COG0152@1|root,COG0152@2|Bacteria,1MUR9@1224|Proteobacteria,42M8A@68525|delta/epsilon subdivisions,2WJY0@28221|Deltaproteobacteria,43UB6@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	PFAM SAICAR synthetase	purC	GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.2.6	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04591	RC00064,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	SAICAR_synt
k59_122438_2	439235.Dalk_3890	7.96e-30	110.0	2EC3H@1|root,3362D@2|Bacteria,1NDXP@1224|Proteobacteria,42WQJ@68525|delta/epsilon subdivisions,2WRNF@28221|Deltaproteobacteria,2MKWZ@213118|Desulfobacterales	28221|Deltaproteobacteria	S	PilZ domain	-	-	-	-	-	-	-	-	-	-	-	-	PilZ
k59_228512_1	411464.DESPIG_02711	2.3e-07	52.4	COG0618@1|root,COG0618@2|Bacteria,1RAUQ@1224|Proteobacteria,42RKG@68525|delta/epsilon subdivisions,2WN0X@28221|Deltaproteobacteria,2M8N4@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	PFAM phosphoesterase RecJ domain protein	-	-	3.1.13.3,3.1.3.7	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
k59_228512_2	1449063.JMLS01000018_gene5930	7.01e-29	108.0	COG0858@1|root,COG0858@2|Bacteria,1VA0P@1239|Firmicutes,4HII1@91061|Bacilli,26YF0@186822|Paenibacillaceae	91061|Bacilli	J	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA	rbfA	-	-	ko:K02834	-	-	-	-	ko00000,ko03009	-	-	-	RBFA
k59_78308_2	1120949.KB903294_gene4622	1.37e-08	58.2	COG2084@1|root,COG2084@2|Bacteria,2GNB0@201174|Actinobacteria,4DIJ9@85008|Micromonosporales	201174|Actinobacteria	I	NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase	-	-	1.1.1.31	ko:K00020	ko00280,ko01100,map00280,map01100	-	R05066	RC00099	ko00000,ko00001,ko01000	-	-	-	NAD_binding_11,NAD_binding_2
k59_10032_1	641491.DND132_3165	1.36e-14	81.3	COG0642@1|root,COG5000@1|root,COG2205@2|Bacteria,COG5000@2|Bacteria,1Q0K1@1224|Proteobacteria,43EQ6@68525|delta/epsilon subdivisions,2X9KG@28221|Deltaproteobacteria,2MERK@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
k59_40273_1	880073.Calab_1785	2.47e-103	320.0	COG0709@1|root,COG1104@1|root,COG0709@2|Bacteria,COG1104@2|Bacteria,2NNVR@2323|unclassified Bacteria	2|Bacteria	E	Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine	selD	-	2.7.9.3,2.8.1.7	ko:K01008,ko:K04487	ko00450,ko00730,ko01100,ko04122,map00450,map00730,map01100,map04122	-	R03595,R07460,R11528,R11529	RC00002,RC01789,RC02313,RC02878	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	AIRS,AIRS_C,Aminotran_5
k59_78310_1	706587.Desti_3092	1.09e-103	315.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,42NB6@68525|delta/epsilon subdivisions,2WNAS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Trypsin	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
k59_70495_1	316067.Geob_1601	2.16e-21	97.8	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42P9E@68525|delta/epsilon subdivisions,2WMH3@28221|Deltaproteobacteria,43SU5@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	histidine kinase, HAMP	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4
k59_214482_1	555779.Dthio_PD1478	3.07e-61	201.0	COG3547@1|root,COG3547@2|Bacteria,1MUER@1224|Proteobacteria,42WT2@68525|delta/epsilon subdivisions,2WR9X@28221|Deltaproteobacteria,2MAU1@213115|Desulfovibrionales	28221|Deltaproteobacteria	L	PFAM transposase IS116 IS110 IS902 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_214482_2	1121405.dsmv_2867	1.8e-23	96.3	COG1910@1|root,COG1910@2|Bacteria,1MVS4@1224|Proteobacteria,42NF7@68525|delta/epsilon subdivisions,2WJA9@28221|Deltaproteobacteria,2MI63@213118|Desulfobacterales	28221|Deltaproteobacteria	P	TIGRFAM DNA binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17,PBP_like
k59_176743_1	32057.KB217478_gene7117	4.4e-43	156.0	COG4191@1|root,COG4191@2|Bacteria,1G0AZ@1117|Cyanobacteria	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
k59_108359_1	7668.SPU_008488-tr	9.24e-71	234.0	KOG1075@1|root,KOG1075@2759|Eukaryota	7668.SPU_008488-tr|-	E	Ribonuclease H protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_47866_1	1232437.KL662043_gene2209	7.37e-80	251.0	COG1145@1|root,COG1145@2|Bacteria,1R1JN@1224|Proteobacteria,42PNJ@68525|delta/epsilon subdivisions,2WKVQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	4fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	1.3.7.1	ko:K20449	ko00760,ko01120,map00760,map01120	-	R03164	RC02422	ko00000,ko00001,ko01000	-	-	-	-
k59_123767_1	335543.Sfum_2303	4.09e-18	84.3	COG2199@1|root,COG3706@2|Bacteria,1QWNG@1224|Proteobacteria,42SDQ@68525|delta/epsilon subdivisions,2WP1N@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
k59_32635_1	1125863.JAFN01000001_gene1830	8.56e-27	112.0	COG0617@1|root,COG0617@2|Bacteria,1MU2X@1224|Proteobacteria,42N0S@68525|delta/epsilon subdivisions,2WJR0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Poly A polymerase, head domain	ccaC	-	2.7.7.19	ko:K00970	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	HD,PolyA_pol,PolyA_pol_RNAbd,tRNA_NucTran2_2
k59_146349_1	1304885.AUEY01000011_gene1749	6.56e-53	190.0	COG2844@1|root,COG2844@2|Bacteria,1MV54@1224|Proteobacteria,42MN5@68525|delta/epsilon subdivisions,2WINN@28221|Deltaproteobacteria,2MI1W@213118|Desulfobacterales	28221|Deltaproteobacteria	O	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen	glnD	-	2.7.7.59	ko:K00990	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	-	-	-	ACT,DUF294,GlnD_UR_UTase,GlnE,HD,NTP_transf_2
k59_222341_1	177437.HRM2_25830	5.42e-95	304.0	COG3850@1|root,COG4191@1|root,COG3850@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42NFY@68525|delta/epsilon subdivisions,2WJKV@28221|Deltaproteobacteria,2MIPK@213118|Desulfobacterales	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_9
k59_108363_1	439235.Dalk_4385	1.01e-22	95.9	COG0411@1|root,COG0411@2|Bacteria,1MUTY@1224|Proteobacteria,42NMG@68525|delta/epsilon subdivisions,2WJ48@28221|Deltaproteobacteria,2MITM@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Branched-chain amino acid ATP-binding cassette transporter	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
k59_108363_2	911045.PSE_2976	4.36e-24	100.0	COG0510@1|root,COG0510@2|Bacteria,1MVBB@1224|Proteobacteria,2TT5Z@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	Choline kinase	-	-	-	-	-	-	-	-	-	-	-	-	Choline_kinase
k59_176747_1	1121430.JMLG01000005_gene686	3.12e-53	173.0	COG1522@1|root,COG1522@2|Bacteria,1V6TH@1239|Firmicutes,24JH9@186801|Clostridia,260KT@186807|Peptococcaceae	186801|Clostridia	K	transcriptional regulator, AsnC family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_AsnC-type
k59_146351_1	1232437.KL662016_gene1006	3.79e-69	227.0	COG2834@1|root,COG2834@2|Bacteria,1PK0I@1224|Proteobacteria,432AX@68525|delta/epsilon subdivisions,2WXRC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Protein of unknown function (DUF1329)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1329
k59_123777_1	1121439.dsat_2572	2.26e-63	214.0	COG0659@1|root,COG0659@2|Bacteria,1MWDF@1224|Proteobacteria,43AD6@68525|delta/epsilon subdivisions,2WJCC@28221|Deltaproteobacteria,2M8PA@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	transporter antisigma-factor antagonist STAS	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
k59_161682_1	177437.HRM2_29480	7.81e-38	145.0	COG0457@1|root,COG0457@2|Bacteria,1MXK4@1224|Proteobacteria,42PK9@68525|delta/epsilon subdivisions,2WM9F@28221|Deltaproteobacteria,2MJ6C@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Oxygen tolerance	-	-	-	-	-	-	-	-	-	-	-	-	BatD
k59_214491_1	82654.Pse7367_1013	1.2e-80	264.0	COG0058@1|root,COG0058@2|Bacteria,1FZUX@1117|Cyanobacteria,1H71S@1150|Oscillatoriales	1117|Cyanobacteria	G	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties	-	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	Phosphorylase
k59_55586_1	563040.Saut_0985	4.86e-09	58.2	COG0715@1|root,COG4191@1|root,COG0715@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,43CE0@68525|delta/epsilon subdivisions,2YTBK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Bacterial periplasmic substrate-binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,NMT1,SBP_bac_3
k59_123780_1	177437.HRM2_21730	2e-144	424.0	COG1966@1|root,COG1966@2|Bacteria,1MWF9@1224|Proteobacteria,42NBI@68525|delta/epsilon subdivisions,2WM33@28221|Deltaproteobacteria,2MIM6@213118|Desulfobacterales	28221|Deltaproteobacteria	T	5TM C-terminal transporter carbon starvation CstA	cstA	-	-	ko:K06200	-	-	-	-	ko00000	-	-	-	CstA,CstA_5TM
k59_85652_1	1054860.KB913030_gene5314	5.16e-06	55.1	COG5184@1|root,COG5184@2|Bacteria,2IG31@201174|Actinobacteria	201174|Actinobacteria	DZ	PFAM regulator of chromosome condensation, RCC1	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,RCC1
k59_17290_1	335543.Sfum_3278	4.6e-101	302.0	COG0150@1|root,COG0150@2|Bacteria,1MURG@1224|Proteobacteria,42KZT@68525|delta/epsilon subdivisions,2WIXY@28221|Deltaproteobacteria,2MR0X@213462|Syntrophobacterales	28221|Deltaproteobacteria	F	PFAM AIR synthase related protein	purM	-	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1844	AIRS,AIRS_C
k59_25090_1	439235.Dalk_1201	1.35e-29	107.0	COG1917@1|root,COG1917@2|Bacteria,1N2Q9@1224|Proteobacteria,42UBE@68525|delta/epsilon subdivisions,2WQDI@28221|Deltaproteobacteria,2MNQC@213118|Desulfobacterales	28221|Deltaproteobacteria	S	PFAM Cupin 2 conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,Cupin_2
k59_25090_2	706587.Desti_2522	4.86e-74	243.0	COG3256@1|root,COG3256@2|Bacteria,1MVT1@1224|Proteobacteria,42NBM@68525|delta/epsilon subdivisions,2WKTG@28221|Deltaproteobacteria,2MRCW@213462|Syntrophobacterales	28221|Deltaproteobacteria	P	Cytochrome C and Quinol oxidase polypeptide I	norZ	-	1.7.2.5	ko:K04561	ko00910,ko01120,map00910,map01120	M00529	R00294	RC02794	ko00000,ko00001,ko00002,ko01000	3.D.4.10	-	-	COX1
k59_85657_1	909663.KI867150_gene2710	8.97e-61	199.0	COG3547@1|root,COG3547@2|Bacteria,1NGR7@1224|Proteobacteria,42NNQ@68525|delta/epsilon subdivisions,2WM2H@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	PFAM transposase IS116 IS110 IS902 family	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_138976_1	1232437.KL662001_gene4576	7.87e-23	101.0	COG0457@1|root,COG0457@2|Bacteria,1RDNA@1224|Proteobacteria,42Q5I@68525|delta/epsilon subdivisions,2WIX0@28221|Deltaproteobacteria,2MJTP@213118|Desulfobacterales	28221|Deltaproteobacteria	T	TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,TPR_11,TPR_16,TPR_19,TPR_2,TPR_4,TPR_7,TPR_8
k59_146365_1	323261.Noc_1747	1.33e-56	199.0	COG1033@1|root,COG1033@2|Bacteria,1QW3H@1224|Proteobacteria,1RZA3@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	TIGRFAM Hopanoid biosynthesis associated RND transporter like protein HpnN	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
k59_154243_1	1278073.MYSTI_00461	8.9e-24	109.0	COG4258@1|root,COG4258@2|Bacteria,1QX46@1224|Proteobacteria,42QK9@68525|delta/epsilon subdivisions,2WKGH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	MMPL family	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
k59_138978_1	1121405.dsmv_1453	9.4e-30	108.0	2E6FN@1|root,3312Z@2|Bacteria,1N6QM@1224|Proteobacteria,42V22@68525|delta/epsilon subdivisions,2WRF9@28221|Deltaproteobacteria,2MM34@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_10052_1	1123228.AUIH01000023_gene3133	8.32e-33	132.0	COG2909@1|root,COG2909@2|Bacteria,1MVZZ@1224|Proteobacteria,1RN29@1236|Gammaproteobacteria,1XMG0@135619|Oceanospirillales	135619|Oceanospirillales	K	ATP-dependent transcriptional regulator	-	-	-	ko:K03556	-	-	-	-	ko00000,ko03000	-	-	-	GerE
k59_115843_1	335543.Sfum_1603	3.95e-117	338.0	COG2344@1|root,COG2344@2|Bacteria,1R55V@1224|Proteobacteria,42M2S@68525|delta/epsilon subdivisions,2WM6N@28221|Deltaproteobacteria,2MQEC@213462|Syntrophobacterales	28221|Deltaproteobacteria	K	Modulates transcription in response to changes in cellular NADH NAD( ) redox state	rex	-	-	ko:K01926	-	-	-	-	ko00000,ko03000	-	-	-	CoA_binding,Put_DNA-bind_N
k59_115843_2	880072.Desac_2886	9.7e-32	115.0	COG0636@1|root,COG0636@2|Bacteria,1NAIE@1224|Proteobacteria,42VAI@68525|delta/epsilon subdivisions,2WRI4@28221|Deltaproteobacteria,2MQNG@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpE	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
k59_207155_2	335543.Sfum_0064	1.86e-44	152.0	COG0548@1|root,COG0548@2|Bacteria,1MU17@1224|Proteobacteria,42N8G@68525|delta/epsilon subdivisions,2WKBC@28221|Deltaproteobacteria,2MQ75@213462|Syntrophobacterales	28221|Deltaproteobacteria	F	Belongs to the acetylglutamate kinase family. ArgB subfamily	argB	GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.2.8	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R02649	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
k59_138984_1	390989.JOEG01000019_gene5888	2.22e-40	139.0	COG1720@1|root,COG1720@2|Bacteria,2IKKT@201174|Actinobacteria,4DE3M@85008|Micromonosporales	201174|Actinobacteria	S	Uncharacterised protein family UPF0066	-	-	-	-	-	-	-	-	-	-	-	-	UPF0066
k59_17295_1	933262.AXAM01000038_gene910	7.6e-35	126.0	COG5401@1|root,COG5401@2|Bacteria,1NA0G@1224|Proteobacteria,42V1V@68525|delta/epsilon subdivisions,2WRCV@28221|Deltaproteobacteria,2MKUK@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Sporulation and spore germination	-	-	-	-	-	-	-	-	-	-	-	-	Germane
k59_25105_1	913865.DOT_3301	1.46e-31	125.0	COG0517@1|root,COG0517@2|Bacteria,1TQ4J@1239|Firmicutes,24B68@186801|Clostridia,260BK@186807|Peptococcaceae	186801|Clostridia	S	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	Y2_Tnp,Zn_Tnp_IS91
k59_93269_1	555779.Dthio_PD1010	7.99e-19	85.5	COG2181@1|root,COG2181@2|Bacteria,1R48S@1224|Proteobacteria,42MZU@68525|delta/epsilon subdivisions,2WKKU@28221|Deltaproteobacteria,2M7X4@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	PFAM Nitrate reductase gamma subunit	dsrM	-	1.7.5.1	ko:K00374	ko00910,ko01120,ko02020,map00910,map01120,map02020	M00529,M00530	R00798,R01106,R09497	RC02812	ko00000,ko00001,ko00002,ko01000	5.A.3.1	-	-	Nitrate_red_gam
k59_93269_2	1487923.DP73_20900	9.13e-48	160.0	2CDHP@1|root,32RXU@2|Bacteria,1VQ7W@1239|Firmicutes,251NF@186801|Clostridia,265N8@186807|Peptococcaceae	186801|Clostridia	S	RsbT co-antagonist protein rsbRD N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RsbRD_N
k59_17297_2	1123009.AUID01000009_gene459	1.41e-24	101.0	COG1521@1|root,COG1521@2|Bacteria,1TR0X@1239|Firmicutes,248PX@186801|Clostridia,268P1@186813|unclassified Clostridiales	186801|Clostridia	K	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis	coaX	-	2.7.1.33	ko:K03525	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Pan_kinase
k59_237458_1	697284.ERIC2_c02030	1.72e-27	115.0	COG0438@1|root,COG0438@2|Bacteria,1U8D6@1239|Firmicutes,4IQ9P@91061|Bacilli,26WJU@186822|Paenibacillaceae	91061|Bacilli	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glycos_transf_1
k59_154771_1	1121396.KB893068_gene1467	5.85e-99	301.0	COG1271@1|root,COG1271@2|Bacteria,1MV60@1224|Proteobacteria,42MB8@68525|delta/epsilon subdivisions,2WIW7@28221|Deltaproteobacteria,2MID8@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM cytochrome bd ubiquinol oxidase subunit I	cydA	-	1.10.3.14	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	Cyt_bd_oxida_I
k59_71021_1	744980.TRICHSKD4_4797	5.75e-54	188.0	COG0330@1|root,COG0330@2|Bacteria,1MW1D@1224|Proteobacteria,2TRE5@28211|Alphaproteobacteria	28211|Alphaproteobacteria	O	SPFH domain / Band 7 family	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
k59_199986_1	316067.Geob_0551	2.5e-54	188.0	COG0215@1|root,COG0215@2|Bacteria,1MV8H@1224|Proteobacteria,42M04@68525|delta/epsilon subdivisions,2WJJD@28221|Deltaproteobacteria,43TS3@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e,tRNA-synt_1g
k59_71023_1	706587.Desti_1915	2.96e-39	145.0	COG1148@1|root,COG1149@1|root,COG1148@2|Bacteria,COG1149@2|Bacteria,1QUM4@1224|Proteobacteria,42MPP@68525|delta/epsilon subdivisions,2WJ3U@28221|Deltaproteobacteria,2MQTI@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_4,Fer4_7,Pyr_redox_2
k59_71023_2	767817.Desgi_3841	6.29e-28	113.0	COG0446@1|root,COG1148@1|root,COG0446@2|Bacteria,COG1148@2|Bacteria,1V5YJ@1239|Firmicutes,248CC@186801|Clostridia	1239|Firmicutes	C	binding domain	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_7,Pyr_redox_2
k59_71023_3	1125863.JAFN01000001_gene2441	2.42e-12	67.0	COG0247@1|root,COG0247@2|Bacteria,1MUMH@1224|Proteobacteria,42N5J@68525|delta/epsilon subdivisions,2WJ6B@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Cysteine-rich domain	bamD	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_17,Fer4_8
k59_86126_1	330214.NIDE0561	1.37e-38	144.0	COG0535@1|root,COG0535@2|Bacteria,3J10V@40117|Nitrospirae	40117|Nitrospirae	C	Iron-sulfur cluster-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM,SPASM
k59_146839_2	933262.AXAM01000039_gene1154	7.2e-17	73.6	2EINH@1|root,33CDW@2|Bacteria,1NN5W@1224|Proteobacteria,42XC5@68525|delta/epsilon subdivisions,2WT26@28221|Deltaproteobacteria,2MMA6@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_154779_2	1121405.dsmv_3736	1.2e-29	112.0	COG1028@1|root,COG1028@2|Bacteria,1MUEV@1224|Proteobacteria,42QAM@68525|delta/epsilon subdivisions,2WM04@28221|Deltaproteobacteria	28221|Deltaproteobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.100,1.1.1.36	ko:K00023,ko:K00059	ko00061,ko00333,ko00630,ko00650,ko00780,ko01040,ko01100,ko01120,ko01130,ko01200,ko01212,map00061,map00333,map00630,map00650,map00780,map01040,map01100,map01120,map01130,map01200,map01212	M00083,M00373,M00572	R01779,R01977,R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00103,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
k59_86132_2	913865.DOT_0875	5.8e-24	98.6	COG2267@1|root,COG2267@2|Bacteria,1VDKR@1239|Firmicutes,24YIZ@186801|Clostridia,264S4@186807|Peptococcaceae	186801|Clostridia	I	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_154785_2	1307436.PBF_04255	2.04e-21	100.0	COG3723@1|root,COG3723@2|Bacteria,1UNDF@1239|Firmicutes,4HB2T@91061|Bacilli,1ZEC2@1386|Bacillus	91061|Bacilli	L	RecT family	recT	-	-	ko:K07455	-	-	-	-	ko00000,ko03400	-	-	-	RecT
k59_207868_1	1265505.ATUG01000001_gene4464	3.91e-10	60.1	COG0642@1|root,COG3437@1|root,COG4191@1|root,COG2205@2|Bacteria,COG3437@2|Bacteria,COG4191@2|Bacteria,1R891@1224|Proteobacteria,42P2C@68525|delta/epsilon subdivisions,2WJZT@28221|Deltaproteobacteria,2MIG9@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
k59_230476_2	1218086.BBNB01000002_gene2609	3.5e-08	55.5	COG1309@1|root,COG1309@2|Bacteria,1NDME@1224|Proteobacteria,1RQQB@1236|Gammaproteobacteria,3WXWN@544|Citrobacter	1236|Gammaproteobacteria	K	Domain of unknown function (DUF1956)	ybiH	GO:0003674,GO:0003700,GO:0005488,GO:0005515,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031333,GO:0031334,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0042802,GO:0043170,GO:0043254,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0046483,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051130,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901576,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2000144,GO:2001141	-	-	-	-	-	-	-	-	-	-	DUF1956,TetR_N
k59_78932_1	880072.Desac_2760	5.6e-50	176.0	COG0013@1|root,COG0013@2|Bacteria,1MU9A@1224|Proteobacteria,42M70@68525|delta/epsilon subdivisions,2WJA8@28221|Deltaproteobacteria,2MQ85@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
k59_78932_2	1479238.JQMZ01000001_gene1203	1.91e-14	72.8	COG0468@1|root,COG0468@2|Bacteria,1MU3C@1224|Proteobacteria,2TRPR@28211|Alphaproteobacteria,43W8I@69657|Hyphomonadaceae	28211|Alphaproteobacteria	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0071496	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
k59_177347_1	269797.Mbar_A2422	6.95e-56	183.0	COG0031@1|root,arCOG01430@2157|Archaea,2XTJR@28890|Euryarchaeota,2NAAJ@224756|Methanomicrobia	224756|Methanomicrobia	E	Cysteine synthase A	-	-	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
k59_56205_1	373994.Riv7116_6899	1.39e-07	57.4	COG1216@1|root,COG1216@2|Bacteria,1G2MT@1117|Cyanobacteria,1HMBH@1161|Nostocales	1117|Cyanobacteria	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_2_C,Glycos_transf_2
k59_169686_1	1121456.ATVA01000011_gene1349	6.54e-31	115.0	2F67A@1|root,33YRB@2|Bacteria,1N6HC@1224|Proteobacteria,42TTW@68525|delta/epsilon subdivisions,2WQHV@28221|Deltaproteobacteria,2MC5S@213115|Desulfovibrionales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_169686_2	1322246.BN4_10942	1.63e-13	67.0	COG0745@1|root,COG0745@2|Bacteria,1NBQZ@1224|Proteobacteria,42V8P@68525|delta/epsilon subdivisions,2WS87@28221|Deltaproteobacteria,2MCPN@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	Response regulator receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
k59_139544_1	990285.RGCCGE502_19365	3.84e-71	228.0	COG3039@1|root,COG3039@2|Bacteria,1MUVI@1224|Proteobacteria,2TSA7@28211|Alphaproteobacteria,4BBSC@82115|Rhizobiaceae	28211|Alphaproteobacteria	L	Transposase domain (DUF772)	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_6,DUF772
k59_223001_1	96561.Dole_3250	3.38e-101	309.0	COG3039@1|root,COG3039@2|Bacteria,1QQ9Q@1224|Proteobacteria,42S7X@68525|delta/epsilon subdivisions,2WNJ2@28221|Deltaproteobacteria,2MJG4@213118|Desulfobacterales	28221|Deltaproteobacteria	L	PFAM transposase IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DUF772
k59_33759_1	1232437.KL662028_gene2798	4.66e-92	282.0	COG1541@1|root,COG1541@2|Bacteria,1MV1W@1224|Proteobacteria,42NKD@68525|delta/epsilon subdivisions,2WIWV@28221|Deltaproteobacteria,2MIVW@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)	-	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C_2
k59_25961_1	596151.DesfrDRAFT_1894	2e-16	75.5	2BJV9@1|root,32E7H@2|Bacteria,1QTNM@1224|Proteobacteria,43ETJ@68525|delta/epsilon subdivisions,2X1Q8@28221|Deltaproteobacteria,2MFGB@213115|Desulfovibrionales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_25961_2	596151.DesfrDRAFT_1895	4.33e-09	57.8	COG1148@1|root,COG1148@2|Bacteria,1QUM4@1224|Proteobacteria,42MPP@68525|delta/epsilon subdivisions,2WJ3U@28221|Deltaproteobacteria,2MEP8@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	4Fe-4S ferredoxin iron-sulfur binding	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_7,Pyr_redox_2
k59_132394_1	1121440.AUMA01000007_gene1215	4.45e-89	267.0	COG0410@1|root,COG0410@2|Bacteria,1MVVC@1224|Proteobacteria,42M9C@68525|delta/epsilon subdivisions,2WJ75@28221|Deltaproteobacteria,2M8GA@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	PFAM ABC transporter related	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
k59_231028_1	367336.OM2255_11790	3.42e-164	473.0	COG1653@1|root,COG1653@2|Bacteria,1R4UG@1224|Proteobacteria,2TUMF@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	ABC transporter substrate-binding protein	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1,SBP_bac_8
k59_200564_1	1089455.MOPEL_009_00150	0.000935	47.8	COG1620@1|root,COG1620@2|Bacteria,2GIUF@201174|Actinobacteria,4F603@85018|Dermatophilaceae	201174|Actinobacteria	C	L-lactate permease	-	-	-	ko:K03303	-	-	-	-	ko00000,ko02000	2.A.14	-	-	Lactate_perm
k59_162573_1	1121413.JMKT01000011_gene2241	9.8e-11	64.7	COG3829@1|root,COG3829@2|Bacteria,1R63H@1224|Proteobacteria,42PJI@68525|delta/epsilon subdivisions,2WK7M@28221|Deltaproteobacteria,2M8XG@213115|Desulfovibrionales	28221|Deltaproteobacteria	K	Bacterial regulatory protein, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Sigma54_activat
k59_86615_1	763034.HMPREF9446_02020	4.84e-08	58.2	COG0745@1|root,COG3292@1|root,COG5002@1|root,COG0745@2|Bacteria,COG3292@2|Bacteria,COG5002@2|Bacteria,4P0IA@976|Bacteroidetes,2FWSR@200643|Bacteroidia,4AN4W@815|Bacteroidaceae	976|Bacteroidetes	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HTH_18,HTH_AraC,HisKA,Reg_prop,Response_reg,Y_Y_Y
k59_64097_1	177437.HRM2_39300	2.17e-67	226.0	COG1032@1|root,COG1032@2|Bacteria,1NAY8@1224|Proteobacteria,42TR8@68525|delta/epsilon subdivisions,2WQC1@28221|Deltaproteobacteria,2MMMU@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
k59_170169_1	118173.KB235914_gene2583	2.58e-74	234.0	COG0399@1|root,COG0399@2|Bacteria,1G0XH@1117|Cyanobacteria,1H93R@1150|Oscillatoriales	1117|Cyanobacteria	E	Belongs to the DegT DnrJ EryC1 family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
k59_170169_2	63737.Npun_R5406	6.44e-05	44.7	COG1045@1|root,COG1045@2|Bacteria,1G2SI@1117|Cyanobacteria,1HJA3@1161|Nostocales	1117|Cyanobacteria	E	PFAM Bacterial transferase hexapeptide (three repeats)	-	-	2.3.1.30	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	M00021	R00586	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep
k59_125059_1	351160.RCIX1106	1.7e-15	82.0	COG1384@1|root,arCOG00485@2157|Archaea,2XTR5@28890|Euryarchaeota,2N9FV@224756|Methanomicrobia	224756|Methanomicrobia	J	Belongs to the class-I aminoacyl-tRNA synthetase family	lysS	-	6.1.1.6	ko:K04566	ko00970,map00970	M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1f
k59_48777_1	876044.IMCC3088_2379	1.74e-24	101.0	COG0664@1|root,COG0664@2|Bacteria,1MXID@1224|Proteobacteria,1S5PP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	Catabolite gene activator and regulatory subunit of cAMP-dependent protein	-	-	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	Crp,HTH_Crp_2,cNMP_binding
k59_33774_1	439235.Dalk_2945	2.91e-83	256.0	COG0468@1|root,COG0468@2|Bacteria,1MU3C@1224|Proteobacteria,42M69@68525|delta/epsilon subdivisions,2WIYC@28221|Deltaproteobacteria,2MI4Q@213118|Desulfobacterales	28221|Deltaproteobacteria	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
k59_200573_1	1121405.dsmv_1967	1.22e-201	578.0	COG1894@1|root,COG1894@2|Bacteria,1MV8F@1224|Proteobacteria,42N6N@68525|delta/epsilon subdivisions,2WJ1W@28221|Deltaproteobacteria,2MMTC@213118|Desulfobacterales	28221|Deltaproteobacteria	C	NADH-ubiquinone oxidoreductase-F iron-sulfur binding region	-	-	1.12.1.3,1.6.5.3	ko:K00124,ko:K00335,ko:K05587,ko:K18331	ko00190,ko00630,ko00680,ko01100,ko01120,ko01200,map00190,map00630,map00680,map01100,map01120,map01200	M00144	R00519,R11945	RC00061,RC02796	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx,Complex1_51K,Fer4,NADH_4Fe-4S,SLBB
k59_185805_1	591019.Shell_1229	1.27e-51	185.0	COG1241@1|root,arCOG03155@1|root,arCOG00439@2157|Archaea,arCOG03155@2157|Archaea,2XQ2Z@28889|Crenarchaeota	28889|Crenarchaeota	L	Belongs to the MCM family	-	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	ko:K10726	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	Intein_splicing,MCM,MCM_N,MCM_OB
k59_192809_2	1120965.AUBV01000015_gene1081	7.44e-11	65.1	COG1087@1|root,COG1087@2|Bacteria,4NEM9@976|Bacteroidetes,47JM5@768503|Cytophagia	976|Bacteroidetes	M	PFAM NAD dependent epimerase dehydratase family	galE	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
k59_71626_1	675814.VIC_001997	0.00025	50.4	COG1404@1|root,COG4935@1|root,COG1404@2|Bacteria,COG4935@2|Bacteria,1MU3S@1224|Proteobacteria,1RNB8@1236|Gammaproteobacteria,1XTS1@135623|Vibrionales	135623|Vibrionales	O	COG1404 Subtilisin-like serine proteases	-	-	-	ko:K14645	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	Inhibitor_I9,PA,PPC,P_proprotein,Peptidase_S8
k59_116869_1	1229172.JQFA01000002_gene2488	2.15e-57	202.0	COG1452@1|root,COG1452@2|Bacteria,1G0TW@1117|Cyanobacteria,1H7RX@1150|Oscillatoriales	1117|Cyanobacteria	M	Mannosyl oligosaccharide glucosidase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_63
k59_231051_1	1121403.AUCV01000001_gene675	3.37e-53	179.0	COG0079@1|root,COG0079@2|Bacteria,1MW7I@1224|Proteobacteria,42NV6@68525|delta/epsilon subdivisions,2WIPB@28221|Deltaproteobacteria,2MIMA@213118|Desulfobacterales	28221|Deltaproteobacteria	E	PFAM aminotransferase class I and II	-	-	4.1.1.81	ko:K04720	ko00860,map00860	-	R06530	RC00517	ko00000,ko00001,ko01000	-	-	-	Aminotran_1_2
k59_25971_1	7668.SPU_009573-tr	1.51e-20	98.2	COG2801@1|root,KOG0017@2759|Eukaryota,39Z2B@33154|Opisthokonta,3BIIP@33208|Metazoa,3D489@33213|Bilateria	33208|Metazoa	L	SCAN domain	-	-	-	-	-	-	-	-	-	-	-	-	RVT_1,SCAN,rve
k59_18381_1	1120971.AUCA01000032_gene3024	3.15e-121	360.0	COG3007@1|root,COG3007@2|Bacteria,1TWIF@1239|Firmicutes,4HCSV@91061|Bacilli	91061|Bacilli	I	Involved in the fatty acid synthesis (FAS II). Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to a coenzyme A (CoA)	fabV	-	1.3.1.44,1.3.1.9	ko:K00209	ko00061,ko00650,ko01100,ko01120,ko01200,ko01212,map00061,map00650,map01100,map01120,map01200,map01212	M00083	R01171,R04429,R04724,R04955,R04958,R04961,R04966,R04969	RC00052,RC00076	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Eno-Rase_FAD_bd,Eno-Rase_NADH_b,Enoyl_reductase
k59_140081_1	753085.F4YCV3_9CAUD	1.32e-117	363.0	4QB5I@10239|Viruses,4QUT2@35237|dsDNA viruses  no RNA stage,4QPQ9@28883|Caudovirales,4QKRP@10699|Siphoviridae	10699|Siphoviridae	S	helicase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_11191_1	1439940.BAY1663_03778	5.16e-06	53.5	COG2861@1|root,COG2861@2|Bacteria,1N3JP@1224|Proteobacteria,1RNKH@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	protein conserved in bacteria	yibQ	-	-	ko:K09798	-	-	-	-	ko00000	-	-	-	Polysacc_deac_2
k59_56689_1	1167006.UWK_01150	8.64e-75	244.0	COG2070@1|root,COG2070@2|Bacteria,1R8ZS@1224|Proteobacteria,42N1N@68525|delta/epsilon subdivisions,2WMIF@28221|Deltaproteobacteria,2MMMQ@213118|Desulfobacterales	28221|Deltaproteobacteria	S	2-Nitropropane dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_79417_1	330214.NIDE3284	3.88e-31	139.0	COG3829@1|root,COG4191@1|root,COG5000@1|root,COG3829@2|Bacteria,COG4191@2|Bacteria,COG5000@2|Bacteria,3J117@40117|Nitrospirae	40117|Nitrospirae	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF3365,HAMP,HATPase_c,HisKA,PAS_4
k59_162586_1	880072.Desac_0830	2.29e-15	71.6	COG0745@1|root,COG0745@2|Bacteria,1PGXZ@1224|Proteobacteria,437JJ@68525|delta/epsilon subdivisions,2X2TK@28221|Deltaproteobacteria,2MSE0@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
k59_18385_1	1121405.dsmv_2196	3.26e-60	203.0	COG1960@1|root,COG1960@2|Bacteria,1MU20@1224|Proteobacteria,42MUH@68525|delta/epsilon subdivisions,2WJ16@28221|Deltaproteobacteria,2MJ7S@213118|Desulfobacterales	28221|Deltaproteobacteria	I	acyl-CoA dehydrogenase	-	-	-	ko:K09456	-	-	-	-	ko00000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_C,Acyl-CoA_dh_M,Acyl-CoA_dh_N,AcylCoA_DH_N
k59_155298_1	717231.Flexsi_0865	7.9e-33	128.0	COG1253@1|root,COG1253@2|Bacteria,2GF7Z@200930|Deferribacteres	200930|Deferribacteres	S	SMART CBS domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,DUF21
k59_116875_1	1245469.S58_52730	0.000469	43.9	COG1917@1|root,COG1917@2|Bacteria,1PJ5Y@1224|Proteobacteria,2TVK5@28211|Alphaproteobacteria,3K6KQ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Cupin	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
k59_140089_2	485918.Cpin_3093	1.1e-09	62.4	COG0513@1|root,COG0513@2|Bacteria,4NEJV@976|Bacteroidetes,1IQEP@117747|Sphingobacteriia	976|Bacteroidetes	L	Belongs to the DEAD box helicase family	deaD	-	3.6.4.13	ko:K05592	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	DEAD,DbpA,Helicase_C
k59_79426_1	289376.THEYE_A1377	2.15e-25	109.0	COG2204@1|root,COG2204@2|Bacteria,3J0C2@40117|Nitrospirae	40117|Nitrospirae	T	Bacterial regulatory protein, Fis family	-	-	-	ko:K13599	ko02020,map02020	M00498	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
k59_56697_1	1283283.ATXA01000001_gene846	1.07e-19	90.9	COG1938@1|root,COG1938@2|Bacteria,2GK10@201174|Actinobacteria,4ERHG@85013|Frankiales	201174|Actinobacteria	S	PAC2 family	-	-	-	-	-	-	-	-	-	-	-	-	PAC2
k59_162875_1	448385.sce7776	2.97e-74	249.0	COG0642@1|root,COG0642@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,42M0Y@68525|delta/epsilon subdivisions,2WJCX@28221|Deltaproteobacteria,2YXI4@29|Myxococcales	28221|Deltaproteobacteria	T	PFAM ATP-binding region ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,Response_reg
k59_231589_1	880072.Desac_1077	6.89e-85	263.0	COG0719@1|root,COG0719@2|Bacteria,1MVKY@1224|Proteobacteria,42NJ3@68525|delta/epsilon subdivisions,2WKHX@28221|Deltaproteobacteria,2MQTA@213462|Syntrophobacterales	28221|Deltaproteobacteria	O	Uncharacterized protein family (UPF0051)	-	-	-	ko:K07033	-	-	-	-	ko00000	-	-	-	UPF0051
k59_201066_1	1382359.JIAL01000001_gene2111	1.17e-21	99.8	COG1956@1|root,COG2203@1|root,COG2208@1|root,COG1956@2|Bacteria,COG2203@2|Bacteria,COG2208@2|Bacteria,3Y358@57723|Acidobacteria,2JIID@204432|Acidobacteriia	204432|Acidobacteriia	T	Sigma factor PP2C-like phosphatases	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	GAF_2,SpoIIE
k59_147502_1	439235.Dalk_2412	2.62e-69	221.0	COG0745@1|root,COG1387@1|root,COG0745@2|Bacteria,COG1387@2|Bacteria,1R9W5@1224|Proteobacteria,42QNF@68525|delta/epsilon subdivisions,2WMV0@28221|Deltaproteobacteria,2MJIA@213118|Desulfobacterales	28221|Deltaproteobacteria	E	SMART phosphoesterase PHP domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PHP
k59_147502_2	96561.Dole_0148	2.27e-30	126.0	COG1305@1|root,COG1305@2|Bacteria,1RARF@1224|Proteobacteria,42R14@68525|delta/epsilon subdivisions,2WN3R@28221|Deltaproteobacteria,2MJNR@213118|Desulfobacterales	28221|Deltaproteobacteria	E	PFAM transglutaminase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
k59_140544_1	1125863.JAFN01000001_gene94	3.28e-143	412.0	COG0473@1|root,COG0473@2|Bacteria,1MUH4@1224|Proteobacteria,42M8G@68525|delta/epsilon subdivisions,2WIYB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate	-	-	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
k59_125443_1	1232437.KL662019_gene628	2.73e-87	265.0	COG3385@1|root,COG3385@2|Bacteria,1NUI6@1224|Proteobacteria,42ZJ8@68525|delta/epsilon subdivisions,2WV27@28221|Deltaproteobacteria,2MND0@213118|Desulfobacterales	28221|Deltaproteobacteria	L	transposase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_201068_2	868595.Desca_2266	2.94e-57	186.0	COG1490@1|root,COG1490@2|Bacteria,1V6GH@1239|Firmicutes,24J90@186801|Clostridia,2626H@186807|Peptococcaceae	186801|Clostridia	J	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality	dtd	-	-	ko:K07560	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Tyr_Deacylase
k59_49178_1	879212.DespoDRAFT_03401	6.16e-25	103.0	COG0618@1|root,COG0618@2|Bacteria,1N0JS@1224|Proteobacteria,42P1S@68525|delta/epsilon subdivisions,2WJV0@28221|Deltaproteobacteria,2MI7M@213118|Desulfobacterales	28221|Deltaproteobacteria	S	PFAM phosphoesterase RecJ domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DHH,DHHA1
k59_41526_1	1232437.KL662031_gene2561	5.12e-99	298.0	COG2206@1|root,COG2206@2|Bacteria,1RAQS@1224|Proteobacteria,42QQI@68525|delta/epsilon subdivisions,2X706@28221|Deltaproteobacteria,2MPNA@213118|Desulfobacterales	28221|Deltaproteobacteria	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HD,HD_5,PAS,PAS_4,PAS_9,Response_reg,sCache_2
k59_117185_1	335543.Sfum_0207	1.76e-08	56.6	COG1009@1|root,COG1009@2|Bacteria,1MW2M@1224|Proteobacteria,42KZE@68525|delta/epsilon subdivisions,2WIPT@28221|Deltaproteobacteria,2MR8Q@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	NADH-Ubiquinone oxidoreductase (complex I), chain 5	nuoL-2	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_C,Proton_antipo_M,Proton_antipo_N
k59_117185_2	335543.Sfum_0206	1.16e-41	139.0	COG0713@1|root,COG0713@2|Bacteria,1RH0S@1224|Proteobacteria,42UWR@68525|delta/epsilon subdivisions,2WQRB@28221|Deltaproteobacteria,2MQNF@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoK	-	1.6.5.3	ko:K00340,ko:K05576	ko00190,ko01100,map00190,map01100	M00144,M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q2
k59_117185_3	452637.Oter_0749	6.54e-31	118.0	COG0839@1|root,COG0839@2|Bacteria	2|Bacteria	C	Belongs to the complex I subunit 6 family	ndhG	-	1.6.5.3	ko:K00339,ko:K05578	ko00190,ko01100,map00190,map01100	M00144,M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q3
k59_34353_1	1265505.ATUG01000001_gene2845	7.42e-54	190.0	COG0768@1|root,COG0768@2|Bacteria,1MV8C@1224|Proteobacteria,42M1S@68525|delta/epsilon subdivisions,2WJ02@28221|Deltaproteobacteria,2MHV4@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Penicillin-binding Protein dimerisation domain	mrdA	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	iAF987.Gmet_0928	PBP_dimer,Transpeptidase
k59_208869_1	1121405.dsmv_1425	4.94e-46	158.0	COG1045@1|root,COG1045@2|Bacteria,1MVFX@1224|Proteobacteria,42MND@68525|delta/epsilon subdivisions,2WJC3@28221|Deltaproteobacteria,2MIG5@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Bacterial transferase hexapeptide (six repeats)	cysE	-	2.3.1.30	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	M00021	R00586	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,SATase_N
k59_215999_1	247490.KSU1_B0100	1.45e-96	292.0	COG3385@1|root,COG3385@2|Bacteria	2|Bacteria	L	transposase activity	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DUF4372
k59_238647_1	177437.HRM2_41050	1.29e-90	277.0	COG0372@1|root,COG0372@2|Bacteria,1MUKX@1224|Proteobacteria,42N8U@68525|delta/epsilon subdivisions,2WJAN@28221|Deltaproteobacteria,2MHQF@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Belongs to the citrate synthase family	citZ	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt,HTH_17
k59_193083_1	350688.Clos_0569	9.16e-61	197.0	COG1526@1|root,COG1526@2|Bacteria,1TU8R@1239|Firmicutes,24G61@186801|Clostridia,36HJU@31979|Clostridiaceae	186801|Clostridia	C	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH	fdhD	-	-	ko:K02379	-	-	-	-	ko00000	-	-	-	FdhD-NarQ
k59_201071_1	909663.KI867150_gene2871	1.5e-147	436.0	COG3039@1|root,COG3039@2|Bacteria,1QY2X@1224|Proteobacteria	1224|Proteobacteria	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_6
k59_140553_1	1121405.dsmv_1666	2.42e-79	262.0	COG0243@1|root,COG0437@1|root,COG0243@2|Bacteria,COG0437@2|Bacteria,1MU1B@1224|Proteobacteria,42NEG@68525|delta/epsilon subdivisions,2WKHA@28221|Deltaproteobacteria,2MMPS@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	actB	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_7,Molybdop_Fe4S4,Molybdopterin,Molydop_binding
k59_216003_1	1265505.ATUG01000001_gene3406	1.61e-70	226.0	COG2984@1|root,COG2984@2|Bacteria,1R84M@1224|Proteobacteria,42PKD@68525|delta/epsilon subdivisions,2WMBV@28221|Deltaproteobacteria,2MJYP@213118|Desulfobacterales	28221|Deltaproteobacteria	S	ABC transporter substrate binding protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC_sub_bind
k59_162888_1	857087.Metme_3441	1.02e-34	134.0	COG0631@1|root,COG3913@1|root,COG0631@2|Bacteria,COG3913@2|Bacteria,1R7UF@1224|Proteobacteria,1S4U5@1236|Gammaproteobacteria,1XG5S@135618|Methylococcales	135618|Methylococcales	T	Serine/threonine phosphatases, family 2C, catalytic domain	-	-	-	ko:K11890	ko02025,map02025	-	-	-	ko00000,ko00001,ko02044	-	-	-	DUF2094,PP2C_2
k59_147509_1	522772.Dacet_0043	8.75e-15	81.6	COG0587@1|root,COG0587@2|Bacteria,2GEJ5@200930|Deferribacteres	200930|Deferribacteres	L	Bacterial DNA polymerase III alpha subunit	-	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
k59_41531_1	1265505.ATUG01000001_gene4782	8.61e-114	339.0	COG0112@1|root,COG0112@2|Bacteria,1MUIS@1224|Proteobacteria,42M0T@68525|delta/epsilon subdivisions,2WJ3C@28221|Deltaproteobacteria,2MHY8@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	-	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
k59_64377_2	1121405.dsmv_1655	6.18e-171	508.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,42Z0I@68525|delta/epsilon subdivisions,2WUFE@28221|Deltaproteobacteria,2MN2T@213118|Desulfobacterales	28221|Deltaproteobacteria	P	heavy metal translocating P-type ATPase	-	-	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
k59_231614_1	515635.Dtur_1454	1.17e-107	322.0	COG1215@1|root,COG1215@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Glyco_tranf_2_3,Glyco_trans_2_3
k59_11800_1	335543.Sfum_0091	7.04e-78	236.0	COG4117@1|root,COG4117@2|Bacteria,1R5GN@1224|Proteobacteria,42QVP@68525|delta/epsilon subdivisions,2WMT7@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM cytochrome B561	cbcB	-	-	-	-	-	-	-	-	-	-	-	Ni_hydr_CYTB
k59_87094_1	177437.HRM2_04480	8.83e-64	207.0	COG1150@1|root,COG1150@2|Bacteria,1QUKA@1224|Proteobacteria,42MNE@68525|delta/epsilon subdivisions,2WIN3@28221|Deltaproteobacteria,2MHSC@213118|Desulfobacterales	28221|Deltaproteobacteria	C	4Fe-4S dicluster domain	qmoC	-	-	ko:K16887	-	-	-	-	ko00000	-	-	-	Fer4_17,Fer4_8,Fer4_9,Nitrate_red_gam
k59_147513_1	177437.HRM2_32620	1.28e-38	137.0	28PNF@1|root,2ZCB7@2|Bacteria,1RA6N@1224|Proteobacteria,42RBI@68525|delta/epsilon subdivisions,2WN4P@28221|Deltaproteobacteria,2MJHU@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_110067_1	335543.Sfum_2759	9.62e-83	257.0	COG0151@1|root,COG0151@2|Bacteria,1MUAH@1224|Proteobacteria,42MCI@68525|delta/epsilon subdivisions,2WJ7H@28221|Deltaproteobacteria,2MQ82@213462|Syntrophobacterales	28221|Deltaproteobacteria	F	Phosphoribosylglycinamide synthetase, C domain	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC,GARS_A,GARS_C,GARS_N
k59_208901_1	1497679.EP56_05975	4.52e-45	155.0	COG0164@1|root,COG0164@2|Bacteria,1V1D6@1239|Firmicutes,4HB7M@91061|Bacilli,26J94@186820|Listeriaceae	91061|Bacilli	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhB	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
k59_34384_1	1121396.KB893077_gene745	1.46e-51	180.0	COG1075@1|root,COG1075@2|Bacteria,1R5PF@1224|Proteobacteria,43BHB@68525|delta/epsilon subdivisions,2X6VQ@28221|Deltaproteobacteria,2MMMX@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Alpha/beta hydrolase of unknown function (DUF915)	-	-	-	-	-	-	-	-	-	-	-	-	DUF915
k59_193095_1	96561.Dole_2313	1.47e-117	352.0	COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,42MEA@68525|delta/epsilon subdivisions,2WIW6@28221|Deltaproteobacteria,2MI74@213118|Desulfobacterales	28221|Deltaproteobacteria	KT	Sigma-54 interaction domain	-	-	2.1.1.80	ko:K00575	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	HTH_8,PAS_4,PAS_9,Sigma54_activat
k59_147514_1	338966.Ppro_1409	2.49e-63	202.0	COG2518@1|root,COG2518@2|Bacteria,1RC4G@1224|Proteobacteria,43E9Z@68525|delta/epsilon subdivisions,2X7S5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	PFAM Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
k59_102634_1	880073.Calab_1130	1.81e-34	129.0	COG1638@1|root,COG1638@2|Bacteria,2NS33@2323|unclassified Bacteria	2|Bacteria	G	Bacterial extracellular solute-binding protein, family 7	-	-	-	ko:K11688,ko:K21395	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.56.1	-	-	DctP
k59_140581_1	240015.ACP_0460	9.58e-60	201.0	COG0038@1|root,COG0038@2|Bacteria,3Y7TT@57723|Acidobacteria,2JMYW@204432|Acidobacteriia	204432|Acidobacteriia	P	Voltage gated chloride channel	-	-	-	ko:K03281	-	-	-	-	ko00000	2.A.49	-	-	Voltage_CLC
k59_11820_1	335543.Sfum_0736	1.76e-67	219.0	COG1171@1|root,COG1171@2|Bacteria,1MVWJ@1224|Proteobacteria,42MKY@68525|delta/epsilon subdivisions,2WM9K@28221|Deltaproteobacteria,2MQRE@213462|Syntrophobacterales	28221|Deltaproteobacteria	E	Pyridoxal-phosphate dependent enzyme	tdcB	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
k59_208913_1	1047013.AQSP01000122_gene2249	9.69e-82	261.0	28NDD@1|root,2ZBG6@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
k59_193102_1	335543.Sfum_0929	2.62e-67	228.0	COG0587@1|root,COG0587@2|Bacteria,1MUIF@1224|Proteobacteria,42MGP@68525|delta/epsilon subdivisions,2WIZ2@28221|Deltaproteobacteria,2MQUW@213462|Syntrophobacterales	28221|Deltaproteobacteria	L	DNA polymerase III alpha subunit	-	-	2.7.7.7	ko:K02337,ko:K14162	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
k59_155741_1	1265505.ATUG01000002_gene1613	7.16e-65	221.0	COG2204@1|root,COG3829@1|root,COG2204@2|Bacteria,COG3829@2|Bacteria,1MU0N@1224|Proteobacteria,43CWU@68525|delta/epsilon subdivisions	1224|Proteobacteria	T	Bacterial regulatory protein, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
k59_57252_1	439235.Dalk_3149	3.93e-25	99.0	COG0817@1|root,COG0817@2|Bacteria,1MUJI@1224|Proteobacteria,42QPX@68525|delta/epsilon subdivisions,2WNF9@28221|Deltaproteobacteria,2MJWT@213118|Desulfobacterales	28221|Deltaproteobacteria	L	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group	ruvC	GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576	3.1.22.4	ko:K01159	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvC
k59_57252_2	933262.AXAM01000015_gene86	7.78e-60	189.0	COG0632@1|root,COG0632@2|Bacteria,1Q5HB@1224|Proteobacteria,42R4Y@68525|delta/epsilon subdivisions,2WMRB@28221|Deltaproteobacteria,2MJPI@213118|Desulfobacterales	28221|Deltaproteobacteria	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB	ruvA	-	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_N
k59_208915_1	1122915.AUGY01000061_gene3759	6.55e-53	179.0	COG3677@1|root,COG3677@2|Bacteria,1V4D1@1239|Firmicutes,4HJM6@91061|Bacilli,26XVB@186822|Paenibacillaceae	91061|Bacilli	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS1595,Zn_Tnp_IS1595
k59_26296_1	1321781.HMPREF1985_02028	5.7e-62	206.0	COG0484@1|root,COG0484@2|Bacteria,1TP00@1239|Firmicutes,4H28A@909932|Negativicutes	909932|Negativicutes	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
k59_26296_3	1125863.JAFN01000001_gene2142	1.68e-54	181.0	COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,42NF6@68525|delta/epsilon subdivisions,2WKVH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
k59_170784_1	1459636.NTE_02683	8.38e-49	166.0	COG0177@1|root,arCOG00459@2157|Archaea,41SFM@651137|Thaumarchaeota	651137|Thaumarchaeota	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD
k59_162908_1	177437.HRM2_09900	1.44e-37	140.0	COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,42M88@68525|delta/epsilon subdivisions,2WIZI@28221|Deltaproteobacteria,2MJ2S@213118|Desulfobacterales	28221|Deltaproteobacteria	T	PFAM sigma-54 factor interaction domain-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,PAS_9,Sigma54_activat
k59_162908_2	1035308.AQYY01000001_gene3239	1.18e-06	50.8	COG0607@1|root,COG0607@2|Bacteria	2|Bacteria	P	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS	-	-	-	ko:K03972	-	-	-	-	ko00000	-	-	-	Rhodanese
k59_216030_1	933262.AXAM01000078_gene1610	1.03e-53	177.0	COG1294@1|root,COG1294@2|Bacteria,1MURP@1224|Proteobacteria,42NHN@68525|delta/epsilon subdivisions,2WJ4S@28221|Deltaproteobacteria,2MHWJ@213118|Desulfobacterales	28221|Deltaproteobacteria	C	TIGRFAM cytochrome d ubiquinol oxidase, subunit II	cydB	-	1.10.3.14	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	Cyt_bd_oxida_II
k59_216030_2	1121920.AUAU01000005_gene937	5.57e-27	107.0	COG1271@1|root,COG1271@2|Bacteria,3Y44V@57723|Acidobacteria	2|Bacteria	C	Cytochrome bd terminal oxidase subunit I	cydA	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016679,GO:0016682,GO:0019646,GO:0020037,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046906,GO:0048037,GO:0055114,GO:0070069,GO:0071944,GO:0097159,GO:1901363	1.10.3.14	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	iPC815.YPO1117,iSBO_1134.SBO_2253,iSFxv_1172.SFxv_0621,iS_1188.S0577,iSbBS512_1146.SbBS512_E2337	Cyt_bd_oxida_I
k59_231650_1	1125863.JAFN01000001_gene214	3.42e-59	196.0	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,42PRI@68525|delta/epsilon subdivisions,2X5GA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
k59_72261_1	1121904.ARBP01000002_gene6986	9.88e-48	173.0	COG0446@1|root,COG0446@2|Bacteria,4PKEU@976|Bacteroidetes,47KJ9@768503|Cytophagia	976|Bacteroidetes	P	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Pyr_redox_dim,Rhodanese
k59_49227_1	644282.Deba_2842	1.31e-74	244.0	COG0243@1|root,COG0243@2|Bacteria,1P01N@1224|Proteobacteria,42M9D@68525|delta/epsilon subdivisions,2WJ43@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	1.8.5.5	ko:K08352	ko00920,ko01120,map00920,map01120	-	R10149	RC02823	ko00000,ko00001,ko01000,ko02000	5.A.3.5	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
k59_11845_1	246200.SPO0289	6.47e-45	153.0	COG2129@1|root,COG2129@2|Bacteria,1R3TH@1224|Proteobacteria,2U5Q8@28211|Alphaproteobacteria,4NA5C@97050|Ruegeria	28211|Alphaproteobacteria	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos_2
k59_11845_2	96561.Dole_0071	0.000473	41.6	COG0655@1|root,COG0655@2|Bacteria,1QV9P@1224|Proteobacteria,42RJT@68525|delta/epsilon subdivisions,2WNM5@28221|Deltaproteobacteria,2MJWR@213118|Desulfobacterales	28221|Deltaproteobacteria	S	NADPH-dependent FMN reductase	-	-	1.6.5.2	ko:K03809	ko00130,ko01110,map00130,map01110	-	R02964,R03643,R03816	RC00819	ko00000,ko00001,ko01000	-	-	-	FMN_red
k59_133025_1	96561.Dole_0565	5.68e-55	184.0	COG0004@1|root,COG0004@2|Bacteria,1NR9F@1224|Proteobacteria,42MFT@68525|delta/epsilon subdivisions,2WIXC@28221|Deltaproteobacteria,2MHRV@213118|Desulfobacterales	28221|Deltaproteobacteria	P	TIGRFAM ammonium transporter	amt	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
k59_133025_2	96561.Dole_0567	9.43e-13	67.8	COG2844@1|root,COG2844@2|Bacteria,1MV54@1224|Proteobacteria,42MN5@68525|delta/epsilon subdivisions,2WINN@28221|Deltaproteobacteria,2MI1W@213118|Desulfobacterales	28221|Deltaproteobacteria	O	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen	glnD	-	2.7.7.59	ko:K00990	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	-	-	-	ACT,DUF294,GlnD_UR_UTase,GlnE,HD,NTP_transf_2
k59_41549_1	264732.Moth_2268	2.5e-96	290.0	COG1063@1|root,COG1063@2|Bacteria,1TPWP@1239|Firmicutes,24ATV@186801|Clostridia,42FBE@68295|Thermoanaerobacterales	186801|Clostridia	C	PFAM Alcohol dehydrogenase GroES domain protein	-	-	1.1.1.14	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	M00014	R00875,R01896	RC00085,RC00102	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N
k59_94951_1	667014.Thein_2069	1.49e-73	249.0	COG1148@1|root,COG1148@2|Bacteria,2GIFP@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	C	Glucose inhibited division protein A	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Pyr_redox_2
k59_72265_1	643648.Slip_1163	5.98e-105	334.0	COG1615@1|root,COG1615@2|Bacteria,1TQHM@1239|Firmicutes,248PM@186801|Clostridia,42JMJ@68298|Syntrophomonadaceae	186801|Clostridia	S	Uncharacterised protein family (UPF0182)	-	-	-	ko:K09118	-	-	-	-	ko00000	-	-	-	UPF0182
k59_216032_1	395961.Cyan7425_3874	3.61e-91	290.0	COG0367@1|root,COG0367@2|Bacteria,1G1WZ@1117|Cyanobacteria,3KI02@43988|Cyanothece	1117|Cyanobacteria	E	TIGRFAM asparagine synthase (glutamine-hydrolyzing)	asnB	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
k59_64398_1	378806.STAUR_0336	9.54e-142	421.0	COG3666@1|root,COG3666@2|Bacteria,1N3QR@1224|Proteobacteria,42R6X@68525|delta/epsilon subdivisions,2WMY9@28221|Deltaproteobacteria,2Z18Z@29|Myxococcales	28221|Deltaproteobacteria	L	COG3666 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_6,DUF772
k59_26309_1	177437.HRM2_30200	2.74e-41	149.0	COG0392@1|root,COG0392@2|Bacteria,1R98C@1224|Proteobacteria,42U6V@68525|delta/epsilon subdivisions,2WKTZ@28221|Deltaproteobacteria,2MJCJ@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
k59_147831_1	494419.ALPM01000048_gene2448	8.82e-23	95.1	COG0411@1|root,COG0411@2|Bacteria,2GMEE@201174|Actinobacteria	201174|Actinobacteria	E	ABC transporter	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
k59_147831_2	1265505.ATUG01000002_gene1743	6.04e-94	288.0	COG0683@1|root,COG0683@2|Bacteria,1MYGR@1224|Proteobacteria,42YJT@68525|delta/epsilon subdivisions,2WU23@28221|Deltaproteobacteria,2MN85@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Receptor family ligand binding region	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
k59_163214_1	439235.Dalk_3415	1.9e-172	518.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2WJN5@28221|Deltaproteobacteria,2MMWB@213118|Desulfobacterales	28221|Deltaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_216464_1	272123.Anacy_3210	1.2e-114	355.0	COG0542@1|root,COG0542@2|Bacteria,1G04Z@1117|Cyanobacteria,1HKJQ@1161|Nostocales	1117|Cyanobacteria	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
k59_163218_1	706587.Desti_3270	5.51e-58	202.0	COG2202@1|root,COG2203@1|root,COG2204@1|root,COG4191@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG2204@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MC4@68525|delta/epsilon subdivisions,2WIU5@28221|Deltaproteobacteria,2MQZQ@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
k59_72748_1	1242864.D187_008877	3.41e-60	199.0	COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,42P5W@68525|delta/epsilon subdivisions,2WMA6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM peptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
k59_133520_1	1307759.JOMJ01000003_gene1755	2.42e-45	163.0	COG4191@1|root,COG4191@2|Bacteria,1R7KQ@1224|Proteobacteria,42PAP@68525|delta/epsilon subdivisions,2WITB@28221|Deltaproteobacteria,2M8JR@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	PFAM ATP-binding region ATPase domain protein	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,dCache_1
k59_49648_1	1139219.I569_00916	4.39e-37	136.0	COG0517@1|root,COG0517@2|Bacteria,1V4CD@1239|Firmicutes,4HGX4@91061|Bacilli,4AZTP@81852|Enterococcaceae	91061|Bacilli	S	Domain in cystathionine beta-synthase and other proteins.	XK27_04065	-	-	ko:K04767	-	-	-	-	ko00000	-	-	-	ACT,CBS
k59_3605_1	573370.DMR_23810	9.05e-30	124.0	COG5000@1|root,COG5000@2|Bacteria,1RHCV@1224|Proteobacteria,42TBY@68525|delta/epsilon subdivisions,2WP6T@28221|Deltaproteobacteria,2M8JS@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	PFAM ATP-binding region ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_4,PAS_9
k59_95422_1	1123290.AUDQ01000013_gene1217	4.83e-44	149.0	COG0231@1|root,COG0231@2|Bacteria,1TR8P@1239|Firmicutes,4H9YX@91061|Bacilli,26D05@186818|Planococcaceae	91061|Bacilli	J	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase	efp	GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
k59_125906_1	1202962.KB907154_gene751	1.97e-06	52.8	29I5E@1|root,3052G@2|Bacteria,1QR7E@1224|Proteobacteria,1SMYW@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Flagellar assembly protein T, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	FlgT_N
k59_103031_1	420324.KI911934_gene181	1.38e-99	305.0	COG5361@1|root,COG5361@2|Bacteria,1PB8E@1224|Proteobacteria,2U4FU@28211|Alphaproteobacteria,1JXIA@119045|Methylobacteriaceae	28211|Alphaproteobacteria	S	Protein of unknown function (DUF1254)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1214,DUF1254
k59_64705_1	1232437.KL662073_gene1727	1.37e-32	118.0	COG2358@1|root,COG2358@2|Bacteria,1MXW1@1224|Proteobacteria,42MR6@68525|delta/epsilon subdivisions,2WITP@28221|Deltaproteobacteria,2MHTE@213118|Desulfobacterales	28221|Deltaproteobacteria	S	TIGRFAM TRAP transporter solute receptor, TAXI family	-	-	-	ko:K07080	-	-	-	-	ko00000	-	-	-	NMT1_3
k59_201573_1	1232437.KL661957_gene2904	1.23e-109	321.0	COG0600@1|root,COG0600@2|Bacteria,1MWDJ@1224|Proteobacteria,42SE1@68525|delta/epsilon subdivisions,2WPX3@28221|Deltaproteobacteria,2MKIX@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02050,ko:K15552	ko00920,ko02010,map00920,map02010	M00188,M00435	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.16,3.A.1.17,3.A.1.17.1,3.A.1.17.4	-	-	BPD_transp_1
k59_193423_1	1499967.BAYZ01000016_gene6501	3.46e-92	290.0	COG0296@1|root,COG0296@2|Bacteria	2|Bacteria	G	1,4-alpha-glucan branching enzyme activity	glgB	GO:0000271,GO:0003674,GO:0003824,GO:0003844,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016020,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033554,GO:0033692,GO:0034637,GO:0034645,GO:0040007,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0055114,GO:0071704,GO:0071944,GO:1901576	2.4.1.18,3.2.1.141,3.2.1.20	ko:K00700,ko:K01187,ko:K01236,ko:K17734	ko00052,ko00500,ko01100,ko01110,map00052,map00500,map01100,map01110	M00565	R00028,R00801,R00802,R02110,R06087,R06088,R09995,R11256	RC00028,RC00049,RC00077	ko00000,ko00001,ko00002,ko01000,ko01002,ko04147	-	CBM48,GH13,GH31	iAPECO1_1312.APECO1_3025,iECNA114_1301.ECNA114_3542,iECOK1_1307.ECOK1_3857,iECS88_1305.ECS88_3830,iECSF_1327.ECSF_3253,iJN678.glgB,iLF82_1304.LF82_0837,iNRG857_1313.NRG857_17030,iUTI89_1310.UTI89_C3941	Alpha-amylase,Alpha-amylase_C,CBM_48
k59_34905_1	96561.Dole_3267	9.53e-24	105.0	COG0784@1|root,COG4191@1|root,COG0784@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42YDH@68525|delta/epsilon subdivisions,2WU7S@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	PAS PAC sensor hybrid histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg,dCache_1
k59_87582_1	1121396.KB893012_gene4054	3.47e-25	101.0	COG0307@1|root,COG0307@2|Bacteria,1MUMB@1224|Proteobacteria,42QT1@68525|delta/epsilon subdivisions,2WNK6@28221|Deltaproteobacteria,2MJM4@213118|Desulfobacterales	28221|Deltaproteobacteria	H	TIGRFAM riboflavin synthase, alpha subunit	ribE	-	2.5.1.9	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00066	RC00958,RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	Lum_binding
k59_223917_2	313628.LNTAR_04151	1.01e-19	93.2	COG1349@1|root,COG1349@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	-	-	3.6.4.12	ko:K02444,ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03000,ko03400	-	-	-	AlbA_2,DUF1670,DeoRC,HATPase_c_4,HTH_DeoR
k59_141112_1	439235.Dalk_1004	2.57e-48	166.0	COG1377@1|root,COG1377@2|Bacteria,1MUWI@1224|Proteobacteria,42NKR@68525|delta/epsilon subdivisions,2WJIQ@28221|Deltaproteobacteria,2MISK@213118|Desulfobacterales	28221|Deltaproteobacteria	N	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin	flhB	-	-	ko:K02401	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	Bac_export_2
k59_12331_1	1167006.UWK_02267	1.04e-50	164.0	COG5499@1|root,COG5499@2|Bacteria,1N89F@1224|Proteobacteria,42XNP@68525|delta/epsilon subdivisions,2WSJU@28221|Deltaproteobacteria,2MNH3@213118|Desulfobacterales	28221|Deltaproteobacteria	K	regulator	-	-	-	ko:K18831	-	-	-	-	ko00000,ko02048,ko03000	-	-	-	HTH_3
k59_117626_1	1522072.IL54_0710	5.34e-05	50.8	COG2801@1|root,COG2963@1|root,COG2801@2|Bacteria,COG2963@2|Bacteria,1PBHA@1224|Proteobacteria,2TRQF@28211|Alphaproteobacteria,2K16S@204457|Sphingomonadales	204457|Sphingomonadales	L	COG2801 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	HTH_32,rve,rve_3
k59_216471_1	246200.SPO3036	1.15e-80	260.0	COG2015@1|root,COG2015@2|Bacteria,1MU82@1224|Proteobacteria,2TSM1@28211|Alphaproteobacteria,4ND2Q@97050|Ruegeria	28211|Alphaproteobacteria	Q	Alkyl sulfatase dimerisation	-	-	-	-	-	-	-	-	-	-	-	-	Alkyl_sulf_C,Alkyl_sulf_dimr,Lactamase_B
k59_178267_2	1403819.BATR01000010_gene354	1.74e-50	166.0	COG4803@1|root,COG4803@2|Bacteria,46VW5@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Protein of unknown function (DUF1269)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1269
k59_178267_3	1294143.H681_14790	4.79e-75	244.0	COG2067@1|root,COG2067@2|Bacteria,1R3SS@1224|Proteobacteria,1S0X2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	long-chain fatty acid transport protein	-	-	-	ko:K06076	-	-	-	-	ko00000,ko02000	1.B.9	-	-	Toluene_X
k59_171243_2	1121405.dsmv_3642	7.54e-43	143.0	COG0049@1|root,COG0049@2|Bacteria,1MXC8@1224|Proteobacteria,42QR7@68525|delta/epsilon subdivisions,2WNFM@28221|Deltaproteobacteria,2MJJG@213118|Desulfobacterales	28221|Deltaproteobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA	rpsG	GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02992	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S7
k59_201578_1	641107.CDLVIII_5309	2.73e-05	51.6	COG1032@1|root,COG1032@2|Bacteria,1UYAF@1239|Firmicutes,24D1D@186801|Clostridia,36WVW@31979|Clostridiaceae	186801|Clostridia	C	PFAM Radical SAM	-	-	1.21.98.3	ko:K04034	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R06268,R06269,R06270	RC00741,RC01491,RC01492	ko00000,ko00001,ko01000	-	-	-	B12-binding,Radical_SAM
k59_110654_1	335543.Sfum_2379	4.41e-68	236.0	COG0784@1|root,COG2202@1|root,COG3829@1|root,COG4191@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG3829@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MC4@68525|delta/epsilon subdivisions,2WIZU@28221|Deltaproteobacteria,2MR92@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_8,PAS_9,PocR,Response_reg,dCache_1
k59_110655_1	1177154.Y5S_01462	5.43e-13	74.3	COG0795@1|root,COG0795@2|Bacteria,1MVW3@1224|Proteobacteria,1RM8H@1236|Gammaproteobacteria,1XIT5@135619|Oceanospirillales	135619|Oceanospirillales	S	permease	lptG	-	-	ko:K11720	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
k59_163228_1	314278.NB231_00520	8.92e-07	55.8	COG0659@1|root,COG0659@2|Bacteria,1MVWV@1224|Proteobacteria,1RMCN@1236|Gammaproteobacteria,1WX2K@135613|Chromatiales	135613|Chromatiales	P	sulphate transporter	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
k59_147864_1	521011.Mpal_0643	1.23e-26	113.0	COG1032@1|root,arCOG01356@2157|Archaea,2XU04@28890|Euryarchaeota,2N9P9@224756|Methanomicrobia	224756|Methanomicrobia	C	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
k59_49673_1	929556.Solca_0499	4.05e-38	142.0	COG4452@1|root,COG4452@2|Bacteria,4NGKY@976|Bacteroidetes,1IPKH@117747|Sphingobacteriia	976|Bacteroidetes	V	Inner membrane protein CreD	creD	-	-	ko:K06143	-	-	-	-	ko00000	-	-	-	CreD
k59_49673_2	1349820.M707_04250	6.16e-06	49.3	COG0318@1|root,COG0318@2|Bacteria,2GIUC@201174|Actinobacteria,1W7ZR@1268|Micrococcaceae	201174|Actinobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
k59_209373_1	1167006.UWK_03338	1.25e-30	114.0	COG0353@1|root,COG0353@2|Bacteria,1MV9Q@1224|Proteobacteria,42QZJ@68525|delta/epsilon subdivisions,2WNCH@28221|Deltaproteobacteria,2MIIY@213118|Desulfobacterales	28221|Deltaproteobacteria	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecR,Toprim_4
k59_87603_1	335543.Sfum_4024	7.36e-86	278.0	COG4285@1|root,COG4285@2|Bacteria,1RH97@1224|Proteobacteria,42TDA@68525|delta/epsilon subdivisions,2WPVZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Biotin-protein ligase, N terminal	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_57695_1	177437.HRM2_10980	1.74e-94	292.0	COG5000@1|root,COG5000@2|Bacteria,1QWMS@1224|Proteobacteria,43BSR@68525|delta/epsilon subdivisions,2X73I@28221|Deltaproteobacteria,2MPJM@213118|Desulfobacterales	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
k59_186773_1	1121403.AUCV01000022_gene3474	1.37e-63	202.0	COG1032@1|root,COG1032@2|Bacteria,1MYYB@1224|Proteobacteria,42N3I@68525|delta/epsilon subdivisions,2WIPK@28221|Deltaproteobacteria,2MJDH@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
k59_238974_1	1232683.ADIMK_1639	3.15e-09	63.2	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,465R0@72275|Alteromonadaceae	1236|Gammaproteobacteria	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal,TarH
k59_110661_1	521674.Plim_2585	7.45e-05	51.2	COG0189@1|root,COG0189@2|Bacteria,2IWYK@203682|Planctomycetes	203682|Planctomycetes	HJ	Belongs to the RimK family	-	-	-	ko:K05844	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	GSH-S_N,RimK
k59_216476_1	998088.B565_1296	1.75e-51	178.0	COG1502@1|root,COG1502@2|Bacteria,1MWUW@1224|Proteobacteria,1RPQG@1236|Gammaproteobacteria,1Y439@135624|Aeromonadales	135624|Aeromonadales	I	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol	cls	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2,PLDc_N
k59_125953_1	1047013.AQSP01000076_gene1475	1.24e-97	290.0	COG0190@1|root,COG0190@2|Bacteria,2NNY1@2323|unclassified Bacteria	2|Bacteria	E	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
k59_181967_1	335543.Sfum_0824	3.27e-97	312.0	COG0493@1|root,COG1148@1|root,COG0493@2|Bacteria,COG1148@2|Bacteria,1MU2H@1224|Proteobacteria,42M6X@68525|delta/epsilon subdivisions,2X6YD@28221|Deltaproteobacteria,2MQTQ@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.17.1.10,1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388,ko:K15022	ko00680,ko00720,ko01100,ko01120,ko01200,map00680,map00720,map01100,map01120,map01200	M00356,M00357,M00377,M00563,M00567	R00134,R04540,R11928,R11931,R11943,R11944	RC00011,RC02796	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_20,Pyr_redox_2
k59_75839_1	96561.Dole_2037	2.07e-105	322.0	COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,42M1X@68525|delta/epsilon subdivisions,2WJA2@28221|Deltaproteobacteria,2MHZK@213118|Desulfobacterales	28221|Deltaproteobacteria	EH	TIGRFAM acetolactate synthase, large subunit, biosynthetic type	ilvB	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
k59_189561_1	933262.AXAM01000004_gene2364	7.96e-73	231.0	COG0438@1|root,COG0438@2|Bacteria,1R8YI@1224|Proteobacteria,42N8I@68525|delta/epsilon subdivisions,2WIYJ@28221|Deltaproteobacteria,2MMJB@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
k59_98602_1	1282876.BAOK01000001_gene1464	1.22e-64	224.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2TQT0@28211|Alphaproteobacteria,4BPAA@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
k59_91004_1	880072.Desac_2814	1.34e-166	479.0	COG4799@1|root,COG4799@2|Bacteria,1MVAX@1224|Proteobacteria,43AEE@68525|delta/epsilon subdivisions,2WIRF@28221|Deltaproteobacteria,2MQFX@213462|Syntrophobacterales	28221|Deltaproteobacteria	I	Acetyl-CoA carboxylase carboxyltransferase component (subunits alpha and beta)	-	-	2.1.3.1,2.1.3.15,6.4.1.3	ko:K01966,ko:K17489	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	M00373,M00741	R00353,R01859	RC00040,RC00097,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
k59_30360_1	251221.35213244	2.1e-73	230.0	COG2801@1|root,COG2801@2|Bacteria,1G5GD@1117|Cyanobacteria	1117|Cyanobacteria	L	PFAM Integrase core domain	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,HTH_Tnp_1,rve
k59_37955_1	439235.Dalk_1816	1.04e-36	137.0	COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,42M88@68525|delta/epsilon subdivisions,2WIZI@28221|Deltaproteobacteria,2MJ2S@213118|Desulfobacterales	28221|Deltaproteobacteria	T	PFAM sigma-54 factor interaction domain-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,PAS_9,Sigma54_activat
k59_91005_1	933262.AXAM01000006_gene1837	4.3e-89	280.0	COG2114@1|root,COG2114@2|Bacteria,1MV1V@1224|Proteobacteria,42SUQ@68525|delta/epsilon subdivisions,2WPIY@28221|Deltaproteobacteria,2MPS7@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc,HAMP
k59_227472_2	335543.Sfum_1970	3.12e-151	430.0	COG0543@1|root,COG0543@2|Bacteria,1R6QZ@1224|Proteobacteria,42MVW@68525|delta/epsilon subdivisions,2WKKC@28221|Deltaproteobacteria,2MQGV@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	Oxidoreductase NAD-binding domain	hdrF	-	-	-	-	-	-	-	-	-	-	-	DHODB_Fe-S_bind,FAD_binding_6,NAD_binding_1
k59_121345_1	1162668.LFE_0763	2.26e-61	202.0	COG0820@1|root,COG0820@2|Bacteria,3J0CH@40117|Nitrospirae	40117|Nitrospirae	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	-	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Fer4_14,Radical_SAM
k59_45542_1	1049564.TevJSym_ad01020	6.22e-16	76.3	COG0811@1|root,COG0811@2|Bacteria,1MX60@1224|Proteobacteria,1RRX1@1236|Gammaproteobacteria,1J5SH@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	U	COG0811 Biopolymer transport proteins	exbB2	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
k59_45542_2	754477.Q7C_1387	1.09e-38	133.0	COG0848@1|root,COG0848@2|Bacteria,1RI4M@1224|Proteobacteria,1S4GX@1236|Gammaproteobacteria	1236|Gammaproteobacteria	U	biopolymer transport protein	exbD	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
k59_174415_3	768710.DesyoDRAFT_1268	2.89e-10	61.2	2C2FS@1|root,3347I@2|Bacteria,1VFU8@1239|Firmicutes,24T1A@186801|Clostridia	186801|Clostridia	S	ASCH domain	-	-	-	-	-	-	-	-	-	-	-	-	ASCH
k59_227478_1	1304874.JAFY01000005_gene1379	3.11e-61	207.0	COG0058@1|root,COG0058@2|Bacteria,3T9UV@508458|Synergistetes	508458|Synergistetes	G	alpha-glucan phosphorylase	glgP	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	Phosphorylase
k59_235067_1	96561.Dole_0549	6.35e-45	147.0	COG0234@1|root,COG0234@2|Bacteria,1MZ2X@1224|Proteobacteria,42U7E@68525|delta/epsilon subdivisions,2WPZP@28221|Deltaproteobacteria,2MKH2@213118|Desulfobacterales	28221|Deltaproteobacteria	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
k59_235067_2	96561.Dole_0550	1.56e-42	152.0	COG0459@1|root,COG0459@2|Bacteria,1MURR@1224|Proteobacteria,42M52@68525|delta/epsilon subdivisions,2WIRK@28221|Deltaproteobacteria,2MHPV@213118|Desulfobacterales	28221|Deltaproteobacteria	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	-	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
k59_174423_1	1267211.KI669560_gene887	8.33e-21	94.4	COG2989@1|root,COG2989@2|Bacteria,4NH3J@976|Bacteroidetes,1INPY@117747|Sphingobacteriia	976|Bacteroidetes	S	L,D-transpeptidase catalytic domain	-	-	-	ko:K21470	-	-	-	-	ko00000,ko01002,ko01011	-	-	-	PG_binding_1,YkuD
k59_22803_1	335543.Sfum_0203	1.09e-109	325.0	COG1005@1|root,COG1005@2|Bacteria,1MU2R@1224|Proteobacteria,42MMX@68525|delta/epsilon subdivisions,2WIX8@28221|Deltaproteobacteria,2MQ5S@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	nuoH	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
k59_181994_1	765914.ThisiDRAFT_1601	4.22e-72	231.0	COG0675@1|root,COG0675@2|Bacteria,1R8FN@1224|Proteobacteria,1SJT3@1236|Gammaproteobacteria,1X0HP@135613|Chromatiales	135613|Chromatiales	L	PFAM Transposase, IS605 OrfB, C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	OrfB_Zn_ribbon
k59_45551_1	1159870.KB907784_gene751	6.75e-35	127.0	COG0410@1|root,COG0410@2|Bacteria,1MUR3@1224|Proteobacteria,2VI3W@28216|Betaproteobacteria,3T1Z2@506|Alcaligenaceae	28216|Betaproteobacteria	E	ABC transporter	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
k59_45551_2	1121403.AUCV01000019_gene3291	1.62e-17	80.1	COG0411@1|root,COG0411@2|Bacteria,1MUTY@1224|Proteobacteria,43AMP@68525|delta/epsilon subdivisions,2X61S@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Branched-chain amino acid ATP-binding cassette transporter	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
k59_174425_1	439235.Dalk_2379	9.7e-97	301.0	COG0369@1|root,COG1151@2|Bacteria,1NYH2@1224|Proteobacteria,42NE1@68525|delta/epsilon subdivisions,2WIVX@28221|Deltaproteobacteria,2MINQ@213118|Desulfobacterales	28221|Deltaproteobacteria	C	TIGRFAM carbon-monoxide dehydrogenase, catalytic subunit	-	-	1.2.7.4	ko:K00198	ko00633,ko00680,ko00720,ko01120,ko01200,map00633,map00680,map00720,map01120,map01200	M00377	R07157,R08034	RC00250,RC02800	ko00000,ko00001,ko00002,ko01000	-	-	-	Prismane
k59_219913_1	288000.BBta_7802	1.64e-103	318.0	COG0465@1|root,COG0465@2|Bacteria,1MU6J@1224|Proteobacteria,2TRNK@28211|Alphaproteobacteria,3JVXA@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	-	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
k59_15209_2	177437.HRM2_08060	3.28e-44	156.0	COG0446@1|root,COG0446@2|Bacteria,1NR3M@1224|Proteobacteria,42N3G@68525|delta/epsilon subdivisions,2WJKF@28221|Deltaproteobacteria,2MJD9@213118|Desulfobacterales	2|Bacteria	C	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain	-	-	1.6.99.3	ko:K03885	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,Pyr_redox_dim
k59_75888_1	393595.ABO_1698	1.19e-38	135.0	COG4333@1|root,COG4333@2|Bacteria,1N19M@1224|Proteobacteria,1SAS8@1236|Gammaproteobacteria,1XQS8@135619|Oceanospirillales	135619|Oceanospirillales	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF1643
k59_68310_1	489825.LYNGBM3L_53820	8.44e-34	119.0	COG0073@1|root,COG0073@2|Bacteria	2|Bacteria	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	-	6.1.1.10,6.1.1.20,6.1.1.6	ko:K01874,ko:K01890,ko:K04566,ko:K06878	ko00450,ko00970,map00450,map00970	M00359,M00360	R03658,R03659,R03660,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,B5,tRNA-synt_1f,tRNA-synt_1g,tRNA_bind
k59_60745_1	335543.Sfum_1219	1.88e-174	495.0	COG0436@1|root,COG0436@2|Bacteria,1MWS8@1224|Proteobacteria,42MEF@68525|delta/epsilon subdivisions,2WJ4D@28221|Deltaproteobacteria,2MQW6@213462|Syntrophobacterales	28221|Deltaproteobacteria	E	PFAM Aminotransferase class I and II	yfdZ	-	2.6.1.83	ko:K10206,ko:K14261	ko00300,ko01100,ko01110,ko01130,ko01230,map00300,map01100,map01110,map01130,map01230	M00527	R07613	RC00006,RC01847	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
k59_60745_2	335543.Sfum_1218	2.06e-141	414.0	COG0460@1|root,COG0460@2|Bacteria,1MUDC@1224|Proteobacteria,42MGS@68525|delta/epsilon subdivisions,2WJ1K@28221|Deltaproteobacteria,2MQ61@213462|Syntrophobacterales	28221|Deltaproteobacteria	E	PFAM Homoserine dehydrogenase	hom	-	1.1.1.3	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00017,M00018	R01773,R01775	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,Homoserine_dh,NAD_binding_3
k59_121364_1	666509.RCA23_c13130	8.49e-159	455.0	COG2801@1|root,COG2801@2|Bacteria,1MZ45@1224|Proteobacteria,2TTG7@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	InterPro IPR001584 COGs COG2801	-	-	-	-	-	-	-	-	-	-	-	-	HTH_29,rve
k59_144109_1	1410676.JNKL01000019_gene1405	0.000799	43.1	COG2208@1|root,COG2208@2|Bacteria,1MXJQ@1224|Proteobacteria,1RQIY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	KT	Stage II sporulation protein E	icfG	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	HAMP,HATPase_c_2,SpoIIE,dCache_1
k59_72_1	1122194.AUHU01000012_gene406	4.6e-39	149.0	COG1048@1|root,COG1048@2|Bacteria,1MU9T@1224|Proteobacteria,1RN5I@1236|Gammaproteobacteria,465HN@72275|Alteromonadaceae	1236|Gammaproteobacteria	C	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate	acnA	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0003994,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006081,GO:0006082,GO:0006091,GO:0006097,GO:0006099,GO:0006101,GO:0006629,GO:0006631,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009060,GO:0009061,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019541,GO:0019679,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044262,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046459,GO:0046487,GO:0046872,GO:0046914,GO:0047456,GO:0048037,GO:0050896,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0072350,GO:0097159,GO:1901363	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	iAPECO1_1312.APECO1_436,iECOK1_1307.ECOK1_1491,iECS88_1305.ECS88_1416,iJN746.PP_2112,iUMN146_1321.UM146_10390,iUTI89_1310.UTI89_C1547	Aconitase,Aconitase_C
k59_136534_1	335543.Sfum_3291	2.38e-47	169.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,42MK5@68525|delta/epsilon subdivisions,2WJ3Z@28221|Deltaproteobacteria,2MQ86@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	PFAM Acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
k59_15210_1	1121396.KB893012_gene4012	1.83e-79	260.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,42M2R@68525|delta/epsilon subdivisions,2WJ4J@28221|Deltaproteobacteria,2MHN2@213118|Desulfobacterales	28221|Deltaproteobacteria	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
k59_15210_2	96561.Dole_1877	7.7e-27	99.4	COG2608@1|root,COG2608@2|Bacteria,1PUDD@1224|Proteobacteria,42XJ7@68525|delta/epsilon subdivisions,2WSKI@28221|Deltaproteobacteria,2MP4U@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Heavy-metal-associated domain	-	-	-	-	-	-	-	-	-	-	-	-	HMA
k59_15210_3	645991.Sgly_2351	4.94e-13	65.1	COG2768@1|root,COG2768@2|Bacteria,1UK08@1239|Firmicutes,25FG6@186801|Clostridia,267F2@186807|Peptococcaceae	186801|Clostridia	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4
k59_7667_1	398512.JQKC01000027_gene3936	5.13e-54	179.0	COG2122@1|root,COG2122@2|Bacteria,1TQ6A@1239|Firmicutes,249KT@186801|Clostridia,3WNIH@541000|Ruminococcaceae	186801|Clostridia	S	PFAM ApbE family	-	-	-	ko:K09740	-	-	-	-	ko00000	-	-	-	-
k59_30399_1	1379281.AVAG01000065_gene1139	1.03e-70	220.0	COG0655@1|root,COG0655@2|Bacteria,1RAK6@1224|Proteobacteria,42QS5@68525|delta/epsilon subdivisions,2WN2M@28221|Deltaproteobacteria,2M7SB@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	PFAM NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
k59_91040_1	379066.GAU_2776	4.73e-20	91.3	COG0515@1|root,COG0515@2|Bacteria,1ZTFJ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	KLT	Serine/Threonine protein kinases, catalytic domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
k59_75917_1	1121405.dsmv_2328	1.57e-50	171.0	COG4972@1|root,COG4972@2|Bacteria,1MX8P@1224|Proteobacteria,42M36@68525|delta/epsilon subdivisions,2WJFJ@28221|Deltaproteobacteria,2MID0@213118|Desulfobacterales	28221|Deltaproteobacteria	NU	TIGRFAM type IV pilus assembly protein PilM	pilM	-	-	ko:K02662	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilM_2
k59_121387_1	497964.CfE428DRAFT_5404	8.3e-46	159.0	COG0429@1|root,COG0429@2|Bacteria,46TRD@74201|Verrucomicrobia	74201|Verrucomicrobia	S	alpha/beta hydrolase fold	-	-	-	ko:K07019	-	-	-	-	ko00000	-	-	-	Abhydrolase_1
k59_128967_1	395019.Bmul_2729	2.06e-56	191.0	COG0014@1|root,COG0014@2|Bacteria,1MUGJ@1224|Proteobacteria,2VJ5M@28216|Betaproteobacteria,1K3QQ@119060|Burkholderiaceae	28216|Betaproteobacteria	E	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate	proA	GO:0003674,GO:0003824,GO:0004350,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0018130,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.2.1.41	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	M00015	R03313	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
k59_182017_1	933262.AXAM01000008_gene1971	1.54e-98	298.0	COG0172@1|root,COG0172@2|Bacteria,1MUJF@1224|Proteobacteria,42M7H@68525|delta/epsilon subdivisions,2WIT7@28221|Deltaproteobacteria,2MI2A@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iAF987.Gmet_3528	Seryl_tRNA_N,tRNA-synt_2b
k59_75923_1	1122217.KB899574_gene2024	8.57e-28	113.0	COG0621@1|root,COG0621@2|Bacteria,1TP2W@1239|Firmicutes,4H28W@909932|Negativicutes	909932|Negativicutes	H	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12	rimO	-	2.8.4.4	ko:K14441	-	-	R10652	RC00003,RC03217	ko00000,ko01000,ko03009	-	-	-	Radical_SAM,TRAM,UPF0004
k59_15236_1	1168289.AJKI01000002_gene2293	2.34e-38	139.0	COG3568@1|root,COG3568@2|Bacteria,4NGUV@976|Bacteroidetes,2FNIX@200643|Bacteroidia,3XJRZ@558415|Marinilabiliaceae	976|Bacteroidetes	S	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
k59_197201_1	1408322.JHYK01000015_gene1902	1.23e-08	55.5	COG0332@1|root,COG0332@2|Bacteria,1TP0K@1239|Firmicutes,248V8@186801|Clostridia,27JH4@186928|unclassified Lachnospiraceae	186801|Clostridia	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
k59_197201_2	1121403.AUCV01000002_gene507	3.54e-13	68.6	COG1399@1|root,COG1399@2|Bacteria,1N7GQ@1224|Proteobacteria,42U2P@68525|delta/epsilon subdivisions,2WRMV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Uncharacterized ACR, COG1399	-	-	-	ko:K07040	-	-	-	-	ko00000	-	-	-	DUF177
k59_227525_1	1265505.ATUG01000003_gene578	3.14e-98	293.0	COG2801@1|root,COG2801@2|Bacteria,1MZ45@1224|Proteobacteria,42MM6@68525|delta/epsilon subdivisions,2WJ53@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	PFAM Integrase catalytic region	-	-	-	-	-	-	-	-	-	-	-	-	HTH_29,rve
k59_227527_1	1121403.AUCV01000002_gene586	1.49e-31	123.0	COG0471@1|root,COG0471@2|Bacteria,1MU0K@1224|Proteobacteria,42MR7@68525|delta/epsilon subdivisions,2WIKA@28221|Deltaproteobacteria,2MMWR@213118|Desulfobacterales	28221|Deltaproteobacteria	P	TrkA-C domain	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS,Na_sulph_symp,TrkA_C
k59_227529_1	459349.CLOAM0964	2.97e-43	160.0	COG0446@1|root,COG0479@1|root,COG1142@1|root,COG1251@1|root,COG0446@2|Bacteria,COG0479@2|Bacteria,COG1142@2|Bacteria,COG1251@2|Bacteria,2NP2E@2323|unclassified Bacteria	2|Bacteria	C	FAD dependent oxidoreductase	nifJ	-	1.12.5.1,1.2.7.1,1.7.1.15	ko:K00205,ko:K00362,ko:K02573,ko:K03737,ko:K05927	ko00010,ko00020,ko00620,ko00650,ko00680,ko00720,ko00910,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00680,map00720,map00910,map01100,map01120,map01130,map01200	M00173,M00307,M00530,M00567	R00787,R01196,R03015,R08060,R10866,R11743	RC00004,RC00176,RC00197,RC00323,RC02742	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	EKR,Fer2_4,Fer2_BFD,Fer4,Fer4_16,Fer4_20,Fer4_7,GXGXG,NiFe_hyd_SSU_C,Oxidored_q6,PFOR_II,POR,POR_N,Pyr_redox_2,TPP_enzyme_C
k59_151802_1	926692.AZYG01000085_gene856	1.56e-62	205.0	COG2801@1|root,COG2801@2|Bacteria,1TU21@1239|Firmicutes,249HN@186801|Clostridia,3WA8E@53433|Halanaerobiales	186801|Clostridia	L	Integrase catalytic region	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve
k59_98738_1	203120.LEUM_1454	1.52e-27	111.0	COG0207@1|root,COG0207@2|Bacteria,1U3AP@1239|Firmicutes,4ID2R@91061|Bacilli,4AX5K@81850|Leuconostocaceae	91061|Bacilli	F	COG0207 Thymidylate synthase	-	-	2.1.1.45	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	M00053	R02101	RC00219,RC00332	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylat_synt
k59_98738_2	264732.Moth_2389	2.02e-16	75.5	COG2131@1|root,COG2131@2|Bacteria,1V3PU@1239|Firmicutes,24HF0@186801|Clostridia,42GBV@68295|Thermoanaerobacterales	186801|Clostridia	F	PFAM CMP dCMP deaminase zinc-binding	comEB	-	3.5.4.12	ko:K01493	ko00240,ko01100,map00240,map01100	M00429	R01663	RC00074	ko00000,ko00001,ko00002,ko01000,ko02044	-	-	-	dCMP_cyt_deam_1
k59_113884_1	1121405.dsmv_3233	8.87e-105	311.0	COG1774@1|root,COG1774@2|Bacteria,1MZBX@1224|Proteobacteria,42NE3@68525|delta/epsilon subdivisions,2WK98@28221|Deltaproteobacteria,2MHSJ@213118|Desulfobacterales	28221|Deltaproteobacteria	S	PFAM PSP1 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PSP1
k59_121485_1	439235.Dalk_2669	1.08e-40	153.0	COG1924@1|root,COG3580@1|root,COG3581@1|root,COG1924@2|Bacteria,COG3580@2|Bacteria,COG3581@2|Bacteria,1PKG6@1224|Proteobacteria,42MY4@68525|delta/epsilon subdivisions,2WJFI@28221|Deltaproteobacteria,2MIP0@213118|Desulfobacterales	28221|Deltaproteobacteria	I	BadF BadG BcrA BcrD	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG,DUF2229
k59_7788_1	1379281.AVAG01000009_gene630	5.55e-60	195.0	COG2181@1|root,COG2181@2|Bacteria,1R48S@1224|Proteobacteria,42MZU@68525|delta/epsilon subdivisions,2WKKU@28221|Deltaproteobacteria,2M7X4@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	PFAM Nitrate reductase gamma subunit	dsrM	-	1.7.5.1	ko:K00374	ko00910,ko01120,ko02020,map00910,map01120,map02020	M00529,M00530	R00798,R01106,R09497	RC02812	ko00000,ko00001,ko00002,ko01000	5.A.3.1	-	-	Nitrate_red_gam
k59_7788_2	933262.AXAM01000094_gene2192	1.26e-23	99.4	COG0247@1|root,COG0247@2|Bacteria,1NZIG@1224|Proteobacteria,42M60@68525|delta/epsilon subdivisions,2WITJ@28221|Deltaproteobacteria,2MHXY@213118|Desulfobacterales	28221|Deltaproteobacteria	C	4Fe-4S dicluster domain	dsrK	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_8
k59_60847_1	1304885.AUEY01000050_gene1189	1.06e-65	213.0	COG1916@1|root,COG1916@2|Bacteria,1MWJ0@1224|Proteobacteria,42P2H@68525|delta/epsilon subdivisions,2WJQM@28221|Deltaproteobacteria,2MI76@213118|Desulfobacterales	28221|Deltaproteobacteria	S	TIGRFAM TraB family protein	-	-	-	-	-	-	-	-	-	-	-	-	TraB
k59_185_1	1121438.JNJA01000061_gene3336	5.44e-49	162.0	COG1484@1|root,COG1484@2|Bacteria,1MWQX@1224|Proteobacteria,42NG2@68525|delta/epsilon subdivisions,2WK33@28221|Deltaproteobacteria,2MGH2@213115|Desulfovibrionales	28221|Deltaproteobacteria	L	PFAM IstB domain protein ATP-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	IstB_IS21
k59_220072_1	1121396.KB893078_gene786	2.66e-78	250.0	COG4467@1|root,COG4467@2|Bacteria,1PPMF@1224|Proteobacteria	1224|Proteobacteria	S	Involved in initiation control of chromosome replication	-	-	-	ko:K07484	-	-	-	-	ko00000	-	-	-	DDE_Tnp_IS66
k59_190_1	350058.Mvan_0238	0.000319	45.4	COG1960@1|root,COG1960@2|Bacteria,2GJIB@201174|Actinobacteria,235J8@1762|Mycobacteriaceae	201174|Actinobacteria	I	Dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_C,Acyl-CoA_dh_M,AcylCoA_DH_N
k59_190_2	224325.AF_1766	2.15e-15	78.6	COG0642@1|root,COG0834@1|root,arCOG01799@2157|Archaea,arCOG06192@2157|Archaea,2Y395@28890|Euryarchaeota,246VU@183980|Archaeoglobi	183980|Archaeoglobi	ET	Bacterial periplasmic substrate-binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_3
k59_197275_1	717785.HYPMC_3361	1.34e-70	228.0	COG0043@1|root,COG0043@2|Bacteria,1MU62@1224|Proteobacteria,2TTSQ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	H	Belongs to the UbiD family	-	-	4.1.1.98	ko:K03182	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04985,R04986	RC00391	ko00000,ko00001,ko00002,ko01000	-	-	-	UbiD
k59_235221_1	439235.Dalk_0495	1.53e-12	72.8	COG0515@1|root,COG0515@2|Bacteria,1R8C8@1224|Proteobacteria,42Q9Y@68525|delta/epsilon subdivisions,2WME3@28221|Deltaproteobacteria,2MJ3C@213118|Desulfobacterales	28221|Deltaproteobacteria	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
k59_60855_1	1304885.AUEY01000005_gene804	4.87e-65	211.0	COG0820@1|root,COG0820@2|Bacteria,1MUYK@1224|Proteobacteria,42N69@68525|delta/epsilon subdivisions,2WIUJ@28221|Deltaproteobacteria,2MJ4T@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Fer4_14,Radical_SAM
k59_91116_1	697281.Mahau_2159	2.07e-94	296.0	COG0480@1|root,COG0480@2|Bacteria,1TPF9@1239|Firmicutes,247VN@186801|Clostridia,42EYD@68295|Thermoanaerobacterales	186801|Clostridia	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
k59_133085_1	1179778.PMM47T1_22807	7.8e-29	116.0	COG2067@1|root,COG2067@2|Bacteria,1R3SS@1224|Proteobacteria,1S0X2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	long-chain fatty acid transport protein	-	-	-	ko:K06076	-	-	-	-	ko00000,ko02000	1.B.9	-	-	Toluene_X
k59_231717_1	1408422.JHYF01000006_gene1028	1.03e-85	268.0	COG0520@1|root,COG0520@2|Bacteria,1TQ1W@1239|Firmicutes,249CS@186801|Clostridia,36EP2@31979|Clostridiaceae	186801|Clostridia	E	TIGRFAM cysteine desulfurase family protein	csd2	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
k59_231717_2	760568.Desku_2913	1.65e-06	50.1	COG1526@1|root,COG1526@2|Bacteria,1TU8R@1239|Firmicutes,24G61@186801|Clostridia,261G6@186807|Peptococcaceae	186801|Clostridia	C	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH	fdhD	-	-	ko:K02379	-	-	-	-	ko00000	-	-	-	FdhD-NarQ
k59_177964_1	1232437.KL662077_gene1918	8.38e-11	60.8	COG0711@1|root,COG0711@2|Bacteria,1NA9K@1224|Proteobacteria,42VN2@68525|delta/epsilon subdivisions,2WR8C@28221|Deltaproteobacteria,2MKBA@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	atpX	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
k59_57330_1	335543.Sfum_0342	1.07e-104	316.0	COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,42M88@68525|delta/epsilon subdivisions,2WIZI@28221|Deltaproteobacteria,2MRE2@213462|Syntrophobacterales	28221|Deltaproteobacteria	KT	PFAM Bacterial regulatory protein, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,PAS_9,Sigma54_activat
k59_72339_1	439235.Dalk_3702	1.95e-59	201.0	COG1519@1|root,COG1519@2|Bacteria,1MU9F@1224|Proteobacteria,42PCH@68525|delta/epsilon subdivisions,2WMQM@28221|Deltaproteobacteria,2MJN5@213118|Desulfobacterales	28221|Deltaproteobacteria	M	PFAM Three-deoxy-D-manno-octulosonic-acid transferase domain protein	kdtA	-	2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15	ko:K02527	ko00540,ko01100,map00540,map01100	M00060,M00080	R04658,R05074,R09763	RC00009,RC00077,RC00247	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT30	-	Glycos_transf_N
k59_216079_2	1340493.JNIF01000004_gene1055	1.08e-34	133.0	COG2204@1|root,COG2204@2|Bacteria,3Y2J1@57723|Acidobacteria	57723|Acidobacteria	T	two component, sigma54 specific, transcriptional regulator, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
k59_170858_1	1304885.AUEY01000056_gene1443	1.08e-76	249.0	COG3316@1|root,COG3316@2|Bacteria,1RHKZ@1224|Proteobacteria,43CRI@68525|delta/epsilon subdivisions,2X7Z7@28221|Deltaproteobacteria,2MIWI@213118|Desulfobacterales	28221|Deltaproteobacteria	L	PFAM Transposase IS66 family	-	-	-	ko:K07484	-	-	-	-	ko00000	-	-	-	DDE_Tnp_IS66,DDE_Tnp_IS66_C,LZ_Tnp_IS66,zf-IS66
k59_170858_2	439235.Dalk_5241	1.56e-46	152.0	COG3436@1|root,COG3436@2|Bacteria,1MZFT@1224|Proteobacteria,42URZ@68525|delta/epsilon subdivisions,2WQ58@28221|Deltaproteobacteria,2MKGK@213118|Desulfobacterales	28221|Deltaproteobacteria	L	PFAM IS66 Orf2 like protein	-	-	-	ko:K07484	-	-	-	-	ko00000	-	-	-	TnpB_IS66
k59_140687_2	572480.Arnit_2205	9.04e-08	54.3	COG0715@1|root,COG0834@1|root,COG2199@1|root,COG2202@1|root,COG0715@2|Bacteria,COG0834@2|Bacteria,COG2202@2|Bacteria,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria	1224|Proteobacteria	T	Diguanylate cyclase	-	-	-	ko:K02030,ko:K03320	-	M00236	-	-	ko00000,ko00002,ko02000	1.A.11,3.A.1.3	-	-	EAL,GGDEF,NMT1,PAS,PAS_3,PAS_9,SBP_bac_3
k59_186401_1	7668.SPU_009575-tr	4.05e-79	265.0	COG2801@1|root,KOG0017@2759|Eukaryota,39Z2B@33154|Opisthokonta,3BIIP@33208|Metazoa,3D489@33213|Bilateria	33208|Metazoa	L	SCAN domain	-	-	-	-	-	-	-	-	-	-	-	-	RVT_1,SCAN,rve
k59_57333_1	690850.Desaf_1972	5.33e-29	106.0	2EF0Y@1|root,338U3@2|Bacteria,1NEBW@1224|Proteobacteria,42VND@68525|delta/epsilon subdivisions,2WSBJ@28221|Deltaproteobacteria,2MDEW@213115|Desulfovibrionales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_57333_2	96561.Dole_2117	7.86e-22	95.1	COG1972@1|root,COG1972@2|Bacteria,1MXXX@1224|Proteobacteria,42PC9@68525|delta/epsilon subdivisions,2WKA4@28221|Deltaproteobacteria,2MJ22@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Na dependent nucleoside transporter	-	-	-	ko:K03317	-	-	-	-	ko00000	2.A.41	-	-	Gate,Nucleos_tra2_C,Nucleos_tra2_N
k59_41582_2	1121405.dsmv_2461	3.27e-87	263.0	COG1250@1|root,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,42M6J@68525|delta/epsilon subdivisions,2WJZQ@28221|Deltaproteobacteria,2MJ1A@213118|Desulfobacterales	28221|Deltaproteobacteria	I	PFAM 3-hydroxyacyl-CoA dehydrogenase	-	-	1.1.1.157,1.1.1.35,4.2.1.17	ko:K00074,ko:K15016	ko00360,ko00362,ko00650,ko00720,ko01100,ko01120,ko01200,map00360,map00362,map00650,map00720,map01100,map01120,map01200	M00374,M00375	R01975,R01976,R03026,R05576,R06941	RC00029,RC00117,RC00831	ko00000,ko00001,ko00002,ko01000	-	-	-	3HCDH,3HCDH_N
k59_95021_1	744985.HIMB59_00002710	0.000131	47.0	COG0584@1|root,COG0584@2|Bacteria,1MW6Z@1224|Proteobacteria,2V43Q@28211|Alphaproteobacteria,4BSD3@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	C	Glycerophosphoryl diester phosphodiesterase family	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
k59_18900_1	1429046.RR21198_1416	9.53e-49	171.0	COG1960@1|root,COG1960@2|Bacteria,2GIX8@201174|Actinobacteria,4FWEK@85025|Nocardiaceae	201174|Actinobacteria	I	acyl-CoA dehydrogenase	mmgC	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
k59_11937_1	237368.SCABRO_00990	1.82e-44	153.0	COG0134@1|root,COG0134@2|Bacteria,2IX3M@203682|Planctomycetes	203682|Planctomycetes	E	Belongs to the TrpC family	trpC	GO:0003674,GO:0003824,GO:0004425,GO:0016829,GO:0016830,GO:0016831	4.1.1.48	ko:K01609	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03508	RC00944	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPS
k59_140694_1	1121441.AUCX01000024_gene1755	5.78e-53	189.0	COG2208@1|root,COG2972@1|root,COG2208@2|Bacteria,COG2972@2|Bacteria,1QCM5@1224|Proteobacteria,435K8@68525|delta/epsilon subdivisions,2WZYM@28221|Deltaproteobacteria,2M8S7@213115|Desulfovibrionales	28221|Deltaproteobacteria	KT	Sigma factor PP2C-like phosphatases	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,SpoIIE
k59_72353_1	96561.Dole_0851	2.75e-25	105.0	COG0366@1|root,COG3408@1|root,COG0366@2|Bacteria,COG3408@2|Bacteria,1MWBZ@1224|Proteobacteria,43AE9@68525|delta/epsilon subdivisions,2X5U3@28221|Deltaproteobacteria,2MJ5S@213118|Desulfobacterales	28221|Deltaproteobacteria	G	alpha amylase catalytic	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase,GDE_C,GDE_N
k59_162957_1	1121405.dsmv_2651	5.91e-145	426.0	COG5421@1|root,COG5421@2|Bacteria,1R3NX@1224|Proteobacteria,42QDV@68525|delta/epsilon subdivisions,2WIRQ@28221|Deltaproteobacteria,2MN1S@213118|Desulfobacterales	68525|delta/epsilon subdivisions	L	PFAM transposase IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
k59_170873_1	1121405.dsmv_2789	2.09e-91	287.0	COG0480@1|root,COG0480@2|Bacteria,1R0V4@1224|Proteobacteria,42M1F@68525|delta/epsilon subdivisions,2WIYM@28221|Deltaproteobacteria,2MHPT@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Elongation factor Tu domain 2	fusA-1	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
k59_49307_1	1121459.AQXE01000015_gene288	2.93e-38	146.0	COG5001@1|root,COG5002@1|root,COG5001@2|Bacteria,COG5002@2|Bacteria,1MU2C@1224|Proteobacteria,43EHM@68525|delta/epsilon subdivisions,2X8EA@28221|Deltaproteobacteria,2MHH2@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS,PAS_9
k59_209474_1	1218075.BAYA01000052_gene6846	2.94e-30	119.0	COG3039@1|root,COG3039@2|Bacteria,1MUVI@1224|Proteobacteria,2VK9J@28216|Betaproteobacteria,1K4IS@119060|Burkholderiaceae	28216|Betaproteobacteria	L	Product type h extrachromosomal origin	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DUF772
k59_171339_1	1304885.AUEY01000053_gene151	1.47e-23	102.0	COG1127@1|root,COG1127@2|Bacteria,1MUSD@1224|Proteobacteria,42NI4@68525|delta/epsilon subdivisions,2WKRT@28221|Deltaproteobacteria,2MIVB@213118|Desulfobacterales	28221|Deltaproteobacteria	Q	PFAM ABC transporter	-	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran,GGDEF
k59_72854_1	335541.Swol_2054	1.18e-08	63.5	COG0426@1|root,COG1251@1|root,COG0426@2|Bacteria,COG1251@2|Bacteria,1TQE9@1239|Firmicutes,249CU@186801|Clostridia,42KEB@68298|Syntrophomonadaceae	186801|Clostridia	C	Metallo-beta-lactamase superfamily	fprA2	-	1.6.3.4	ko:K22405	-	-	-	-	ko00000,ko01000	-	-	-	Flavodoxin_1,Lactamase_B,Pyr_redox_2
k59_239058_2	992406.RIA_1420	1.3e-13	72.4	COG1040@1|root,COG1040@2|Bacteria,4NNI1@976|Bacteroidetes,1I22C@117743|Flavobacteriia	976|Bacteroidetes	S	amidophosphoribosyl-transferase	comF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	Pribosyltran
k59_87708_2	177437.HRM2_31670	1.58e-100	301.0	COG0437@1|root,COG0437@2|Bacteria,1NBU3@1224|Proteobacteria,42MNU@68525|delta/epsilon subdivisions,2WJRG@28221|Deltaproteobacteria,2MIME@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein	dsrO	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_11,Fer4_4
k59_87708_3	1123376.AUIU01000015_gene472	1.29e-21	87.0	arCOG10385@1|root,32SEM@2|Bacteria	2|Bacteria	-	-	dsrJ	-	-	-	-	-	-	-	-	-	-	-	-
k59_209486_1	177437.HRM2_48210	7.5e-76	238.0	COG0701@1|root,COG0701@2|Bacteria,1MUN8@1224|Proteobacteria,42N6E@68525|delta/epsilon subdivisions,2WJXG@28221|Deltaproteobacteria,2MJ1N@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Predicted permease	-	-	-	ko:K07089	-	-	-	-	ko00000	-	-	-	ArsP_1
k59_141222_1	909663.KI867150_gene944	7.87e-36	134.0	COG0499@1|root,COG0499@2|Bacteria,1MUQ2@1224|Proteobacteria,42M83@68525|delta/epsilon subdivisions,2WIZE@28221|Deltaproteobacteria,2MQA7@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine	ahcY	-	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
k59_178401_1	941449.dsx2_1083	1.3e-73	240.0	COG0367@1|root,COG0367@2|Bacteria,1MW4E@1224|Proteobacteria,42MEI@68525|delta/epsilon subdivisions,2WJEG@28221|Deltaproteobacteria,2M88F@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	TIGRFAM asparagine synthase (glutamine-hydrolyzing)	asnB	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
k59_80510_2	1307759.JOMJ01000003_gene1158	7.64e-87	264.0	COG0765@1|root,COG0765@2|Bacteria,1MX3E@1224|Proteobacteria,42MFY@68525|delta/epsilon subdivisions,2WJS5@28221|Deltaproteobacteria,2M877@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	polar amino acid ABC transporter, inner membrane subunit	-	-	-	ko:K02029	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	BPD_transp_1
k59_216603_1	1265505.ATUG01000001_gene4508	6.72e-87	269.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WKFQ@28221|Deltaproteobacteria,2MIXP@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains	-	-	-	ko:K07713	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
k59_224045_1	1265505.ATUG01000002_gene1691	5.53e-65	209.0	COG0306@1|root,COG0306@2|Bacteria,1PNTZ@1224|Proteobacteria,42MXE@68525|delta/epsilon subdivisions,2WIRG@28221|Deltaproteobacteria,2MPZ0@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Phosphate transporter family	-	-	-	-	-	-	-	-	-	-	-	-	PHO4
k59_49776_1	177437.HRM2_41800	1.62e-160	467.0	2DBU2@1|root,2ZB3S@2|Bacteria,1N1MT@1224|Proteobacteria,42VJX@68525|delta/epsilon subdivisions,2WSPP@28221|Deltaproteobacteria,2MNKM@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_4
k59_12492_1	1265505.ATUG01000001_gene2927	1.12e-33	132.0	COG1960@1|root,COG1960@2|Bacteria,1MU20@1224|Proteobacteria,42MUH@68525|delta/epsilon subdivisions,2WJ16@28221|Deltaproteobacteria,2MHYV@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Acyl-CoA dehydrogenase N terminal	-	-	-	ko:K09456	-	-	-	-	ko00000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_C,Acyl-CoA_dh_M,Acyl-CoA_dh_N,AcylCoA_DH_N
k59_209496_1	1040989.AWZU01000112_gene4443	6.2e-92	281.0	COG2801@1|root,COG2801@2|Bacteria,1MVXQ@1224|Proteobacteria,2U0FG@28211|Alphaproteobacteria,3JX5H@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	L	COG2801 Transposase and inactivated derivatives	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve
k59_147972_1	1041146.ATZB01000008_gene2192	2.96e-78	253.0	28HMZ@1|root,2Z7WD@2|Bacteria,1MU3Q@1224|Proteobacteria,2TSGX@28211|Alphaproteobacteria,4BCDP@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Protein of unknown function (DUF3604)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3604
k59_133643_1	742742.HMPREF9452_02080	2.38e-21	98.2	COG4974@1|root,COG4974@2|Bacteria,2GNDP@201174|Actinobacteria,4CUM8@84998|Coriobacteriia	201174|Actinobacteria	D	Belongs to the 'phage' integrase family. XerC subfamily	-	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
k59_201709_1	879212.DespoDRAFT_01991	6.67e-62	202.0	COG1559@1|root,COG1559@2|Bacteria,1MUQF@1224|Proteobacteria,42MPA@68525|delta/epsilon subdivisions,2WJ0Q@28221|Deltaproteobacteria,2MI3R@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation	mltG	-	-	ko:K07082	-	-	-	-	ko00000	-	-	-	YceG
k59_186862_1	1304885.AUEY01000034_gene1876	5.31e-55	179.0	COG3417@1|root,COG3417@2|Bacteria,1RA6V@1224|Proteobacteria,42UKY@68525|delta/epsilon subdivisions,2WR6E@28221|Deltaproteobacteria,2MPC5@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Peptidoglycan-synthase activator LpoB	-	-	-	ko:K07337	-	-	-	-	ko00000	-	-	-	LpoB
k59_133649_1	1121405.dsmv_1369	5.6e-56	182.0	COG2834@1|root,COG2834@2|Bacteria,1PDTV@1224|Proteobacteria,42TAB@68525|delta/epsilon subdivisions,2WPXY@28221|Deltaproteobacteria,2MK70@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)	lolA	-	-	ko:K03634	-	-	-	-	ko00000	-	-	-	LolA
k59_64828_1	1121440.AUMA01000010_gene317	6.93e-55	192.0	COG3850@1|root,COG4191@1|root,COG3850@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42NFY@68525|delta/epsilon subdivisions,2WJKV@28221|Deltaproteobacteria,2M7VM@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	PFAM ATP-binding region ATPase domain protein	-	-	2.7.13.3	ko:K02482,ko:K10819	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_9
k59_64828_2	1121440.AUMA01000010_gene312	1.31e-35	124.0	COG0745@1|root,COG0745@2|Bacteria,1NBDV@1224|Proteobacteria,42UVC@68525|delta/epsilon subdivisions,2WQ45@28221|Deltaproteobacteria,2MBV0@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	PFAM response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
k59_3767_1	933262.AXAM01000050_gene3482	6.16e-81	257.0	COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,42NCR@68525|delta/epsilon subdivisions,2WKMY@28221|Deltaproteobacteria,2MHTZ@213118|Desulfobacterales	28221|Deltaproteobacteria	V	ABC transporter transmembrane region	-	-	-	ko:K06147,ko:K18889	ko02010,map02010	M00707	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.106,3.A.1.106.13,3.A.1.106.5,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
k59_186866_1	933262.AXAM01000052_gene2016	8.82e-79	248.0	COG2199@1|root,COG3706@2|Bacteria,1R8F2@1224|Proteobacteria,42QMA@68525|delta/epsilon subdivisions,2WKC1@28221|Deltaproteobacteria,2MHN4@213118|Desulfobacterales	28221|Deltaproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	DUF484,GGDEF
k59_216618_1	880072.Desac_0829	6.03e-73	234.0	COG0527@1|root,COG0527@2|Bacteria,1NAE6@1224|Proteobacteria,42VF1@68525|delta/epsilon subdivisions,2WSF3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	aspartate kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_232286_1	696281.Desru_1189	1.45e-10	62.4	COG1592@1|root,COG1853@1|root,COG1592@2|Bacteria,COG1853@2|Bacteria,1V3CX@1239|Firmicutes,24IC2@186801|Clostridia,261SK@186807|Peptococcaceae	186801|Clostridia	C	PFAM Flavin reductase like domain	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
k59_232286_2	177437.HRM2_32050	5.79e-11	60.8	COG3086@1|root,COG3086@2|Bacteria,1PKXC@1224|Proteobacteria,42UU9@68525|delta/epsilon subdivisions,2WPMZ@28221|Deltaproteobacteria,2MK8X@213118|Desulfobacterales	28221|Deltaproteobacteria	T	PFAM Positive regulator of sigma(E) RseC MucC	-	-	-	ko:K03803	-	-	-	-	ko00000,ko03021	-	-	-	RseC_MucC
k59_72868_1	335543.Sfum_0020	3.43e-63	215.0	COG1067@1|root,COG1067@2|Bacteria,1MWGB@1224|Proteobacteria,42NJD@68525|delta/epsilon subdivisions,2WJFK@28221|Deltaproteobacteria,2MQ92@213462|Syntrophobacterales	28221|Deltaproteobacteria	O	Belongs to the peptidase S16 family	-	-	3.4.21.53	ko:K01338,ko:K04076	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA_32,Lon_C
k59_171377_1	1307759.JOMJ01000003_gene901	1.51e-77	259.0	COG0568@1|root,COG0568@2|Bacteria,1MVNJ@1224|Proteobacteria,42N2S@68525|delta/epsilon subdivisions,2WJ0E@28221|Deltaproteobacteria,2M7SM@213115|Desulfovibrionales	28221|Deltaproteobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	rpoD	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_ner,Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
k59_148005_1	177439.DP0499	3.21e-79	246.0	COG2145@1|root,COG2145@2|Bacteria,1MVES@1224|Proteobacteria,42PAR@68525|delta/epsilon subdivisions,2WMWU@28221|Deltaproteobacteria,2MJHN@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)	thiM	-	2.7.1.50	ko:K00878	ko00730,ko01100,map00730,map01100	M00127	R04448	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HK
k59_103202_1	933262.AXAM01000044_gene1408	5.15e-43	154.0	COG3385@1|root,COG3385@2|Bacteria,1MVRM@1224|Proteobacteria,42U5W@68525|delta/epsilon subdivisions,2WQUQ@28221|Deltaproteobacteria,2MKFC@213118|Desulfobacterales	28221|Deltaproteobacteria	L	PFAM transposase IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,Nterm_IS4
k59_193597_1	1121405.dsmv_2894	7.41e-84	250.0	COG4747@1|root,COG4747@2|Bacteria,1RG0Y@1224|Proteobacteria,42RJV@68525|delta/epsilon subdivisions,2WNZV@28221|Deltaproteobacteria,2MJW9@213118|Desulfobacterales	28221|Deltaproteobacteria	S	ACT domain protein	-	-	-	-	-	-	-	-	-	-	-	-	ACT
k59_72873_1	439235.Dalk_2209	8e-99	298.0	COG3264@1|root,COG3264@2|Bacteria,1MWSA@1224|Proteobacteria,42NUP@68525|delta/epsilon subdivisions,2WKSD@28221|Deltaproteobacteria,2MNKG@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Mechanosensitive ion channel	mscS-1	-	-	ko:K16052	-	-	-	-	ko00000,ko02000	1.A.23.4	-	-	MS_channel
k59_12508_1	880072.Desac_0652	1.53e-114	335.0	COG1830@1|root,COG1830@2|Bacteria,1MWJW@1224|Proteobacteria,42NP9@68525|delta/epsilon subdivisions,2WIP9@28221|Deltaproteobacteria,2MRSW@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	DeoC/LacD family aldolase	aroA'	-	4.1.2.13	ko:K11645	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	DeoC
k59_12508_2	439235.Dalk_1759	7.96e-27	107.0	COG1465@1|root,COG1465@2|Bacteria,1P42W@1224|Proteobacteria,42MQM@68525|delta/epsilon subdivisions,2WK5X@28221|Deltaproteobacteria,2MIRC@213118|Desulfobacterales	28221|Deltaproteobacteria	E	3-dehydroquinate synthase (EC 4.6.1.3)	-	-	1.4.1.24	ko:K11646	ko00400,ko01110,ko01130,map00400,map01110,map01130	-	R08569	RC02302	ko00000,ko00001,ko01000	-	-	-	DHQS
k59_80545_2	637905.SVI_3142	7.12e-23	101.0	COG1574@1|root,COG1574@2|Bacteria,1MWP2@1224|Proteobacteria,1RNB7@1236|Gammaproteobacteria,2Q9PB@267890|Shewanellaceae	1236|Gammaproteobacteria	S	PFAM Amidohydrolase 3	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
k59_57835_1	335543.Sfum_2328	9.14e-89	271.0	COG0189@1|root,COG0189@2|Bacteria,1QX79@1224|Proteobacteria,42P6H@68525|delta/epsilon subdivisions,2WKP1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	HJ	ATP-grasp domain	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_3
k59_110799_2	1459636.NTE_00783	5.39e-14	67.0	COG1998@1|root,arCOG04183@2157|Archaea,41SWB@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Belongs to the eukaryotic ribosomal protein eS31 family	rps27ae	-	-	ko:K02977	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko04147	-	-	-	Ribosomal_S27
k59_183589_1	240016.ABIZ01000001_gene1763	9.28e-39	141.0	COG1354@1|root,COG1354@2|Bacteria,46UBD@74201|Verrucomicrobia,2IUKJ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	D	Segregation and condensation protein ScpA	-	-	-	-	-	-	-	-	-	-	-	-	SMC_ScpA
k59_123118_2	382464.ABSI01000011_gene3132	1.34e-23	99.4	COG0330@1|root,COG0330@2|Bacteria,46X93@74201|Verrucomicrobia,2IV2B@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	C-terminal region of band_7	-	-	-	-	-	-	-	-	-	-	-	-	Band_7,Band_7_C
k59_123121_1	1167006.UWK_03239	1.35e-50	173.0	COG0673@1|root,COG0673@2|Bacteria,1MV7C@1224|Proteobacteria,42NV0@68525|delta/epsilon subdivisions,2WK1Y@28221|Deltaproteobacteria,2MHUD@213118|Desulfobacterales	28221|Deltaproteobacteria	S	PFAM oxidoreductase domain protein	gnnA	-	-	ko:K09949	-	-	-	-	ko00000	-	-	iAF987.Gmet_2352	GFO_IDH_MocA,GFO_IDH_MocA_C
k59_1617_1	596151.DesfrDRAFT_3630	1.41e-32	129.0	COG4191@1|root,COG4191@2|Bacteria,1P0U1@1224|Proteobacteria,42PTP@68525|delta/epsilon subdivisions,2WJ8U@28221|Deltaproteobacteria,2M8NY@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
k59_1618_1	1510531.JQJJ01000013_gene38	1.16e-15	77.4	COG0500@1|root,COG2226@2|Bacteria,1RFDN@1224|Proteobacteria,2UEKT@28211|Alphaproteobacteria,3K32C@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
k59_1618_2	234267.Acid_5472	2.41e-32	127.0	COG0457@1|root,COG0457@2|Bacteria,3Y3RA@57723|Acidobacteria	57723|Acidobacteria	M	SMART Tetratricopeptide	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2,TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8
k59_236792_1	404589.Anae109_3879	5.76e-46	164.0	COG0769@1|root,COG0769@2|Bacteria,1MU6P@1224|Proteobacteria,42NKY@68525|delta/epsilon subdivisions,2WJJG@28221|Deltaproteobacteria,2YU1E@29|Myxococcales	28221|Deltaproteobacteria	M	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008765,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
k59_62520_2	981336.F944_01437	3.54e-18	87.4	COG1253@1|root,COG1253@2|Bacteria,1QTUN@1224|Proteobacteria,1RMTY@1236|Gammaproteobacteria,3NIPV@468|Moraxellaceae	1236|Gammaproteobacteria	P	Transporter associated domain	yoaE	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,TerC
k59_47287_1	933262.AXAM01000002_gene503	5.14e-30	119.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,1MU1Q@1224|Proteobacteria,42ND6@68525|delta/epsilon subdivisions,2WIJS@28221|Deltaproteobacteria,2MHY5@213118|Desulfobacterales	28221|Deltaproteobacteria	G	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	Carb_kinase,YjeF_N
k59_47287_2	1397528.Q671_16375	1.37e-17	77.8	COG0736@1|root,COG0736@2|Bacteria,1MZBF@1224|Proteobacteria,1S98P@1236|Gammaproteobacteria,1XKU7@135619|Oceanospirillales	135619|Oceanospirillales	I	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein	acpS	-	2.7.8.7	ko:K00997	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	-	ACPS
k59_183609_1	714943.Mucpa_6180	3.13e-54	178.0	COG0388@1|root,COG0388@2|Bacteria,4NE37@976|Bacteroidetes,1INZJ@117747|Sphingobacteriia	976|Bacteroidetes	S	Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	yafV	-	3.5.1.3	ko:K13566	ko00250,map00250	-	R00269,R00348	RC00010	ko00000,ko00001,ko01000	-	-	-	CN_hydrolase
k59_236799_1	439235.Dalk_3033	1.49e-18	85.5	COG0004@1|root,COG0004@2|Bacteria,1NR9F@1224|Proteobacteria,42M8M@68525|delta/epsilon subdivisions,2WJE2@28221|Deltaproteobacteria,2MISS@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Ammonium Transporter	-	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
k59_1629_1	1238184.CM001792_gene3545	8.96e-05	49.3	COG1309@1|root,COG1309@2|Bacteria,1UX6P@1239|Firmicutes,4I447@91061|Bacilli,23N3Z@182709|Oceanobacillus	91061|Bacilli	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
k59_229192_1	765420.OSCT_0760	7.03e-44	162.0	COG2366@1|root,COG2366@2|Bacteria,2G63N@200795|Chloroflexi,376RD@32061|Chloroflexia	32061|Chloroflexia	S	PFAM peptidase S45 penicillin amidase	-	-	3.5.1.11	ko:K01434	ko00311,ko01130,map00311,map01130	-	R02170	RC00166,RC00328	ko00000,ko00001,ko01000,ko01002	-	-	-	Penicil_amidase
k59_1637_1	439235.Dalk_1965	2.06e-65	216.0	COG4191@1|root,COG4191@2|Bacteria,1QUMH@1224|Proteobacteria,42MM2@68525|delta/epsilon subdivisions,2WJBF@28221|Deltaproteobacteria,2MHM2@213118|Desulfobacterales	28221|Deltaproteobacteria	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
k59_115279_1	1121405.dsmv_3382	5.42e-75	242.0	COG0111@1|root,COG0111@2|Bacteria,1MU5Z@1224|Proteobacteria,42M1C@68525|delta/epsilon subdivisions,2WIZQ@28221|Deltaproteobacteria,2MHQ6@213118|Desulfobacterales	28221|Deltaproteobacteria	E	D-isomer specific 2-hydroxyacid dehydrogenase catalytic	-	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C,ACT
k59_107831_1	1121405.dsmv_3265	5.73e-05	46.6	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,42N89@68525|delta/epsilon subdivisions,2WIUT@28221|Deltaproteobacteria,2MN57@213118|Desulfobacterales	28221|Deltaproteobacteria	O	Trypsin	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
k59_107831_2	177437.HRM2_06720	1.5e-33	129.0	COG1032@1|root,COG5011@1|root,COG1032@2|Bacteria,COG5011@2|Bacteria,1MV5G@1224|Proteobacteria,42MPT@68525|delta/epsilon subdivisions,2WJG9@28221|Deltaproteobacteria,2MHW1@213118|Desulfobacterales	28221|Deltaproteobacteria	C	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	DUF2344,Radical_SAM
k59_123155_1	1177154.Y5S_01610	2.2e-28	117.0	COG0154@1|root,COG0154@2|Bacteria,1MWWQ@1224|Proteobacteria,1RMKH@1236|Gammaproteobacteria,1XIWD@135619|Oceanospirillales	135619|Oceanospirillales	J	Belongs to the amidase family	-	-	3.5.1.4	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	-	R02540,R03096,R03180,R03909,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000	-	-	-	Amidase
k59_85054_1	335543.Sfum_1683	6.05e-118	348.0	COG1541@1|root,COG1541@2|Bacteria,1MV1W@1224|Proteobacteria,42NKD@68525|delta/epsilon subdivisions,2WIWV@28221|Deltaproteobacteria,2MR0M@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)	paaK-2	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	iAF987.Gmet_1825	AMP-binding,AMP-binding_C_2
k59_69958_1	1121405.dsmv_0100	1.08e-67	209.0	COG2316@1|root,COG2316@2|Bacteria,1RA50@1224|Proteobacteria,42QZZ@68525|delta/epsilon subdivisions,2WMUN@28221|Deltaproteobacteria,2MJHQ@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	-	-	-	-	-	-	-	-	-	HD
k59_69958_2	1304874.JAFY01000001_gene2576	6.67e-10	61.6	COG3437@1|root,COG3437@2|Bacteria,3TCKE@508458|Synergistetes	508458|Synergistetes	KT	PFAM metal-dependent phosphohydrolase HD sub domain	-	-	-	-	-	-	-	-	-	-	-	-	CHASE2,HD
k59_138335_1	1121439.dsat_2182	1.79e-38	146.0	COG1150@1|root,COG2181@1|root,COG1150@2|Bacteria,COG2181@2|Bacteria,1R44N@1224|Proteobacteria,42NTE@68525|delta/epsilon subdivisions,2WJN8@28221|Deltaproteobacteria,2M8U1@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_17,Fer4_8,Nitrate_red_gam
k59_213944_1	1042377.AFPJ01000051_gene87	1.42e-94	291.0	COG3119@1|root,COG3119@2|Bacteria,1MUJH@1224|Proteobacteria,1RN2V@1236|Gammaproteobacteria,46DHJ@72275|Alteromonadaceae	1236|Gammaproteobacteria	P	Sulfatase	aslA	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase,Sulfatase_C
k59_69967_1	1173029.JH980292_gene690	2.09e-05	52.8	COG4191@1|root,COG4191@2|Bacteria,1G2MR@1117|Cyanobacteria,1HA47@1150|Oscillatoriales	1117|Cyanobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,PAS_9
k59_16790_1	439235.Dalk_2830	1.49e-104	322.0	COG2208@1|root,COG2972@1|root,COG2208@2|Bacteria,COG2972@2|Bacteria,1R7WZ@1224|Proteobacteria,42Q3R@68525|delta/epsilon subdivisions,2WM5A@28221|Deltaproteobacteria,2MIDF@213118|Desulfobacterales	28221|Deltaproteobacteria	KT	Sigma factor PP2C-like phosphatases	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	GAF_2,SSF,SpoIIE
k59_100433_1	498761.HM1_0663	7.43e-47	164.0	COG0340@1|root,COG1654@1|root,COG0340@2|Bacteria,COG1654@2|Bacteria,1TQCU@1239|Firmicutes,248CK@186801|Clostridia	186801|Clostridia	HK	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor	birA	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_C,BPL_LplA_LipB,HTH_11
k59_1672_2	487796.Flav2ADRAFT_1114	4.82e-05	50.4	COG2931@1|root,COG3210@1|root,COG3266@1|root,COG4625@1|root,COG4733@1|root,COG5644@1|root,COG2931@2|Bacteria,COG3210@2|Bacteria,COG3266@2|Bacteria,COG4625@2|Bacteria,COG4733@2|Bacteria,COG5644@2|Bacteria	2|Bacteria	H	endopeptidase inhibitor activity	yddG	-	3.4.24.40	ko:K01406,ko:K03201,ko:K07451,ko:K13613,ko:K19360	ko01503,ko03070,map01503,map03070	M00333	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko01004,ko01008,ko02044,ko02048,ko03036	3.A.7	-	-	DUF4335,HemolysinCabind,Phage-tail_3
k59_213957_1	314270.RB2083_2750	5.5e-72	231.0	COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,2TQNK@28211|Alphaproteobacteria	1224|Proteobacteria	G	COG1593 TRAP-type C4-dicarboxylate transport system, large permease component	MA20_18685	-	-	-	-	-	-	-	-	-	-	-	DctM
k59_1681_1	1499967.BAYZ01000048_gene2698	2.13e-187	531.0	COG2907@1|root,COG2907@2|Bacteria,2NS11@2323|unclassified Bacteria	2|Bacteria	S	Flavin containing amine oxidoreductase	-	-	-	ko:K06954	-	-	-	-	ko00000	-	-	-	Amino_oxidase,NAD_binding_8
k59_47334_1	888832.HMPREF9420_0926	1.17e-18	85.5	COG1028@1|root,COG1028@2|Bacteria,4NEAI@976|Bacteroidetes,2FNB4@200643|Bacteroidia	976|Bacteroidetes	IQ	reductase	fabG	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
k59_39725_2	1278073.MYSTI_01922	3.3e-40	155.0	COG4228@1|root,COG4228@2|Bacteria,1R4HU@1224|Proteobacteria,42Y6H@68525|delta/epsilon subdivisions,2WUJZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	DNA circulation	-	-	-	-	-	-	-	-	-	-	-	-	DNA_circ_N
k59_39725_3	411464.DESPIG_00863	2.03e-61	208.0	COG4379@1|root,COG4379@2|Bacteria,1MX68@1224|Proteobacteria,42RQV@68525|delta/epsilon subdivisions,2WNV4@28221|Deltaproteobacteria,2MAZ0@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Tail protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_39725_5	690850.Desaf_0705	7.15e-32	118.0	COG4381@1|root,COG4381@2|Bacteria,1N954@1224|Proteobacteria,430E3@68525|delta/epsilon subdivisions,2WVTH@28221|Deltaproteobacteria,2MCQV@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Phage protein GP46	-	-	-	-	-	-	-	-	-	-	-	-	GP46
k59_39725_6	1000565.METUNv1_01740	5.04e-48	172.0	COG3299@1|root,COG3299@2|Bacteria,1PYEJ@1224|Proteobacteria,2VRSP@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Baseplate J family protein	-	-	-	-	-	-	-	-	-	-	-	-	Baseplate_J
k59_92680_1	700598.Niako_1437	1.98e-31	121.0	COG0702@1|root,COG0702@2|Bacteria,4NGMK@976|Bacteroidetes,1IRD8@117747|Sphingobacteriia	976|Bacteroidetes	GM	PFAM NmrA-like family	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10,NmrA
k59_206580_1	459495.SPLC1_S201490	5.03e-13	68.6	COG0306@1|root,COG0306@2|Bacteria,1G13U@1117|Cyanobacteria	1117|Cyanobacteria	P	PFAM phosphate transporter	-	-	-	ko:K03306	-	-	-	-	ko00000	2.A.20	-	-	PHO4
k59_206580_2	1265505.ATUG01000002_gene1690	9.3e-32	119.0	COG1392@1|root,COG1392@2|Bacteria	2|Bacteria	P	Protein of unknown function DUF47	-	-	-	ko:K07220	-	-	-	-	ko00000	-	-	-	PhoU_div
k59_85077_1	113355.CM001775_gene2197	3.9e-17	85.9	COG4644@1|root,COG4644@2|Bacteria,1G1DD@1117|Cyanobacteria	1117|Cyanobacteria	L	COG4644 Transposase and inactivated derivatives TnpA family	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_Tn3,DUF4158
k59_168458_1	589865.DaAHT2_1333	1.56e-37	145.0	COG0745@1|root,COG0784@1|root,COG2203@1|root,COG2770@1|root,COG3437@1|root,COG4251@1|root,COG0745@2|Bacteria,COG0784@2|Bacteria,COG2203@2|Bacteria,COG2770@2|Bacteria,COG3437@2|Bacteria,COG4251@2|Bacteria,1NC9X@1224|Proteobacteria,43BZ2@68525|delta/epsilon subdivisions,2X79T@28221|Deltaproteobacteria,2MPN3@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,GAF_2,HAMP,HATPase_c,HisKA,Response_reg
k59_47343_1	933262.AXAM01000002_gene525	2.42e-50	180.0	COG0449@1|root,COG0449@2|Bacteria,1MW4K@1224|Proteobacteria,42KZ7@68525|delta/epsilon subdivisions,2WJP6@28221|Deltaproteobacteria,2MIWZ@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	iAF987.Gmet_1487	GATase_6,SIS
k59_198953_1	471854.Dfer_1397	7.21e-08	60.5	COG2152@1|root,COG2152@2|Bacteria,4NJA9@976|Bacteroidetes,47P20@768503|Cytophagia	976|Bacteroidetes	G	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_107883_1	177437.HRM2_38620	1.01e-23	99.8	COG2414@1|root,COG2414@2|Bacteria,1MWBB@1224|Proteobacteria,42NR7@68525|delta/epsilon subdivisions,2WK49@28221|Deltaproteobacteria,2MHYC@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Aldehyde ferredoxin oxidoreductase	-	-	1.2.7.5	ko:K03738	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00309	R08571	RC00242	ko00000,ko00001,ko00002,ko01000	-	-	-	AFOR_C,AFOR_N
k59_39750_1	1121405.dsmv_2224	1.64e-72	245.0	COG0577@1|root,COG2234@1|root,COG0577@2|Bacteria,COG2234@2|Bacteria,1MVYE@1224|Proteobacteria,42PKN@68525|delta/epsilon subdivisions,2WIWP@28221|Deltaproteobacteria,2MIQI@213118|Desulfobacterales	28221|Deltaproteobacteria	V	FtsX-like permease family	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,PA,Peptidase_M28
k59_213985_1	880072.Desac_0364	1.01e-64	212.0	COG0402@1|root,COG0402@2|Bacteria,1MVPA@1224|Proteobacteria,42NI6@68525|delta/epsilon subdivisions,2WKI1@28221|Deltaproteobacteria,2MQBT@213462|Syntrophobacterales	28221|Deltaproteobacteria	F	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine	mtaD	-	3.5.4.28,3.5.4.31	ko:K12960	ko00270,ko01100,map00270,map01100	-	R09660	RC00477	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
k59_130764_1	113355.CM001775_gene3795	2.76e-48	163.0	COG1121@1|root,COG1121@2|Bacteria,1G2EJ@1117|Cyanobacteria	1117|Cyanobacteria	P	ABC transporter	-	-	-	ko:K09817	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ABC_tran
k59_176172_1	335543.Sfum_1239	2.27e-71	233.0	COG0342@1|root,COG0342@2|Bacteria,1MV5U@1224|Proteobacteria,42M6V@68525|delta/epsilon subdivisions,2WJCI@28221|Deltaproteobacteria,2MR54@213462|Syntrophobacterales	28221|Deltaproteobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
k59_161132_1	246197.MXAN_5363	7.11e-22	96.3	COG0061@1|root,COG0061@2|Bacteria,1MUBC@1224|Proteobacteria,42MP8@68525|delta/epsilon subdivisions,2WKMR@28221|Deltaproteobacteria,2YUYM@29|Myxococcales	28221|Deltaproteobacteria	H	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	nadK	-	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	NAD_kinase
k59_115332_1	1499967.BAYZ01000028_gene1333	4.2e-53	186.0	COG3829@1|root,COG3829@2|Bacteria,2NQNU@2323|unclassified Bacteria	2|Bacteria	KT	Sigma-54 interaction domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HTH_8,Sigma54_activat
k59_77787_1	768671.ThimaDRAFT_4561	1.83e-48	162.0	COG0628@1|root,COG0628@2|Bacteria,1MVX7@1224|Proteobacteria,1RNN1@1236|Gammaproteobacteria,1WXTE@135613|Chromatiales	135613|Chromatiales	S	Pfam:UPF0118	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
k59_47356_1	926692.AZYG01000085_gene856	5.14e-61	201.0	COG2801@1|root,COG2801@2|Bacteria,1TU21@1239|Firmicutes,249HN@186801|Clostridia,3WA8E@53433|Halanaerobiales	186801|Clostridia	L	Integrase catalytic region	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve
k59_9416_1	933262.AXAM01000084_gene1046	6.45e-88	269.0	COG0624@1|root,COG0624@2|Bacteria,1NYRF@1224|Proteobacteria,42SSP@68525|delta/epsilon subdivisions,2WP84@28221|Deltaproteobacteria,2MN7M@213118|Desulfobacterales	28221|Deltaproteobacteria	E	peptidase	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer
k59_115333_1	335543.Sfum_0121	1.83e-193	550.0	COG0459@1|root,COG0459@2|Bacteria,1MURR@1224|Proteobacteria,42M52@68525|delta/epsilon subdivisions,2WIRK@28221|Deltaproteobacteria,2MRAR@213462|Syntrophobacterales	28221|Deltaproteobacteria	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	-	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
k59_108284_1	760568.Desku_1076	6.05e-77	252.0	COG1148@1|root,COG1908@1|root,COG1148@2|Bacteria,COG1908@2|Bacteria,1UT78@1239|Firmicutes,24A6H@186801|Clostridia,26171@186807|Peptococcaceae	186801|Clostridia	C	Methyl-viologen-reducing hydrogenase, delta subunit	-	-	-	ko:K16886	-	-	-	-	ko00000	-	-	-	Fer4,Fer4_9,FlpD,Pyr_redox_2
k59_17185_1	658172.CKC_05465	0.000159	50.8	COG0749@1|root,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,2TRJF@28211|Alphaproteobacteria,4B86G@82115|Rhizobiaceae	28211|Alphaproteobacteria	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
k59_131233_2	933262.AXAM01000069_gene2684	2.27e-23	99.8	COG1190@1|root,COG1190@2|Bacteria,1MX1V@1224|Proteobacteria,42M90@68525|delta/epsilon subdivisions,2WJ9G@28221|Deltaproteobacteria,2MHV2@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Belongs to the class-II aminoacyl-tRNA synthetase family	lysS	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
k59_199392_1	1232437.KL662050_gene5287	8.83e-184	523.0	COG1055@1|root,COG1055@2|Bacteria,1MXKG@1224|Proteobacteria,42PAX@68525|delta/epsilon subdivisions,2WKEP@28221|Deltaproteobacteria,2MN68@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Putative citrate transport	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS_2
k59_40193_1	338966.Ppro_0674	1.63e-131	411.0	COG0086@1|root,COG0086@2|Bacteria,1MU3M@1224|Proteobacteria,42NAW@68525|delta/epsilon subdivisions,2WISU@28221|Deltaproteobacteria,43UIG@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	-	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
k59_17190_1	1353529.M899_0024	1.77e-25	106.0	COG1005@1|root,COG1005@2|Bacteria,1MU2R@1224|Proteobacteria,42MMX@68525|delta/epsilon subdivisions,2MSXI@213481|Bdellovibrionales,2WIX8@28221|Deltaproteobacteria	213481|Bdellovibrionales	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	nuoH	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh,PDZ_2
k59_17190_2	383372.Rcas_2091	2.93e-42	151.0	COG0649@1|root,COG0649@2|Bacteria,2G5JF@200795|Chloroflexi,37504@32061|Chloroflexia	32061|Chloroflexia	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoD2	-	1.6.5.3	ko:K00333	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_49kDa
k59_51190_2	1492922.GY26_16060	4.56e-11	68.6	COG4653@1|root,COG4653@2|Bacteria,1PF7B@1224|Proteobacteria,1TKHN@1236|Gammaproteobacteria,1JBN6@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Phage capsid family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_capsid
k59_59496_1	1121405.dsmv_0970	1.29e-85	268.0	COG0119@1|root,COG0119@2|Bacteria,1MUNQ@1224|Proteobacteria,42MAV@68525|delta/epsilon subdivisions,2WJC9@28221|Deltaproteobacteria,2MIPJ@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Belongs to the alpha-IPM synthase homocitrate synthase family	cimA	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
k59_28194_1	589865.DaAHT2_1125	1.18e-06	51.6	COG0463@1|root,COG3216@1|root,COG0463@2|Bacteria,COG3216@2|Bacteria,1QTWH@1224|Proteobacteria,43D0B@68525|delta/epsilon subdivisions,2X8CP@28221|Deltaproteobacteria,2MPN2@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Uncharacterized protein conserved in bacteria (DUF2062)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2062,Glycos_transf_2
k59_28194_2	1121403.AUCV01000014_gene4644	5.43e-24	100.0	COG4261@1|root,COG4261@2|Bacteria,1MVXJ@1224|Proteobacteria,42TFF@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	lipid A biosynthesis acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Lip_A_acyltrans
k59_104721_1	177437.HRM2_17430	2.28e-41	149.0	COG0104@1|root,COG0104@2|Bacteria,1MU5B@1224|Proteobacteria,42M9E@68525|delta/epsilon subdivisions,2WJ3F@28221|Deltaproteobacteria,2MI7I@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
k59_135295_1	177437.HRM2_46080	9.66e-58	191.0	COG0842@1|root,COG0842@2|Bacteria,1Q99P@1224|Proteobacteria,42M53@68525|delta/epsilon subdivisions,2WMEY@28221|Deltaproteobacteria,2MIY1@213118|Desulfobacterales	28221|Deltaproteobacteria	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane,ABC2_membrane_3
k59_225642_1	1449069.JMLO01000010_gene379	3.2e-05	52.0	COG0654@1|root,COG0654@2|Bacteria,2GK88@201174|Actinobacteria,4FV9E@85025|Nocardiaceae	201174|Actinobacteria	CH	FAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3
k59_195020_1	1121405.dsmv_3691	1.11e-93	285.0	COG3547@1|root,COG3547@2|Bacteria,1NP2U@1224|Proteobacteria,43A5Q@68525|delta/epsilon subdivisions,2X2AM@28221|Deltaproteobacteria,2MPDW@213118|Desulfobacterales	28221|Deltaproteobacteria	L	Transposase (IS116 IS110 IS902 family)	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_225644_1	1122918.KB907260_gene1931	2.69e-29	119.0	COG1653@1|root,COG1653@2|Bacteria,1TPWV@1239|Firmicutes,4HEIR@91061|Bacilli,275IK@186822|Paenibacillaceae	91061|Bacilli	G	Extracellular solute-binding protein	-	-	-	ko:K17318	ko02010,map02010	M00603	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.29,3.A.1.1.9	-	-	DUF3502,SBP_bac_1,SBP_bac_8
k59_74305_1	1235803.C825_04573	4.06e-07	58.5	COG0845@1|root,COG0845@2|Bacteria,4NERP@976|Bacteroidetes,2FPPN@200643|Bacteroidia,22WZ1@171551|Porphyromonadaceae	976|Bacteroidetes	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
k59_28216_1	439235.Dalk_3213	9.96e-77	248.0	COG1022@1|root,COG1022@2|Bacteria,1MU4D@1224|Proteobacteria,42N2G@68525|delta/epsilon subdivisions,2WIXB@28221|Deltaproteobacteria,2MHUE@213118|Desulfobacterales	28221|Deltaproteobacteria	I	PFAM AMP-dependent synthetase and ligase	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
k59_188439_1	759914.BP951000_0013	7.64e-35	131.0	COG1847@1|root,COG1847@2|Bacteria,2J5S0@203691|Spirochaetes	203691|Spirochaetes	S	PFAM Single-stranded nucleic acid binding R3H	jag	-	-	ko:K06346	-	-	-	-	ko00000	-	-	-	Jag_N,KH_4,R3H
k59_188439_2	335543.Sfum_2599	9.59e-82	259.0	COG0486@1|root,COG0486@2|Bacteria,1MUCQ@1224|Proteobacteria,42M6T@68525|delta/epsilon subdivisions,2WIWY@28221|Deltaproteobacteria,2MQAK@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34	mnmE	-	-	ko:K03650	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko01000,ko03016	-	-	-	MMR_HSR1,MnmE_helical,TrmE_N
k59_66318_1	1121405.dsmv_1967	8.4e-102	314.0	COG1894@1|root,COG1894@2|Bacteria,1MV8F@1224|Proteobacteria,42N6N@68525|delta/epsilon subdivisions,2WJ1W@28221|Deltaproteobacteria,2MMTC@213118|Desulfobacterales	28221|Deltaproteobacteria	C	NADH-ubiquinone oxidoreductase-F iron-sulfur binding region	-	-	1.12.1.3,1.6.5.3	ko:K00124,ko:K00335,ko:K05587,ko:K18331	ko00190,ko00630,ko00680,ko01100,ko01120,ko01200,map00190,map00630,map00680,map01100,map01120,map01200	M00144	R00519,R11945	RC00061,RC02796	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx,Complex1_51K,Fer4,NADH_4Fe-4S,SLBB
k59_36555_1	443143.GM18_0017	1.55e-41	150.0	COG2067@1|root,COG2067@2|Bacteria,1MV7W@1224|Proteobacteria,42NZ4@68525|delta/epsilon subdivisions,2WQTT@28221|Deltaproteobacteria,43VJV@69541|Desulfuromonadales	28221|Deltaproteobacteria	I	Outer membrane protein transport protein (OMPP1/FadL/TodX)	-	-	-	ko:K06076	-	-	-	-	ko00000,ko02000	1.B.9	-	-	Toluene_X
k59_233994_1	335543.Sfum_0463	6.53e-30	110.0	2ECCP@1|root,336AZ@2|Bacteria,1N9PN@1224|Proteobacteria,42W93@68525|delta/epsilon subdivisions,2WRXB@28221|Deltaproteobacteria,2MS3Z@213462|Syntrophobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Rho_N
k59_89488_1	933262.AXAM01000096_gene2623	9.22e-48	167.0	COG3039@1|root,COG3039@2|Bacteria,1R6NB@1224|Proteobacteria,42RBZ@68525|delta/epsilon subdivisions,2WMWZ@28221|Deltaproteobacteria,2MQ2G@213118|Desulfobacterales	28221|Deltaproteobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_142833_1	706587.Desti_4771	7.33e-90	276.0	COG0407@1|root,COG0407@2|Bacteria,1R9IN@1224|Proteobacteria,42Q1Q@68525|delta/epsilon subdivisions,2WMDE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	PFAM Uroporphyrinogen decarboxylase (URO-D)	-	-	-	-	-	-	-	-	-	-	-	-	URO-D
k59_14138_2	665942.HMPREF1022_03100	9.65e-09	53.1	COG1146@1|root,COG1146@2|Bacteria,1QWQ4@1224|Proteobacteria,43BUY@68525|delta/epsilon subdivisions,2X75X@28221|Deltaproteobacteria,2MHB0@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_7
k59_14141_1	1408473.JHXO01000008_gene2751	2.81e-09	59.7	2E5Q2@1|root,330EP@2|Bacteria,4NUMS@976|Bacteroidetes,2FUW0@200643|Bacteroidia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_36570_1	1121405.dsmv_3151	7.16e-57	197.0	COG0699@1|root,COG0699@2|Bacteria,1R3WJ@1224|Proteobacteria,42N0G@68525|delta/epsilon subdivisions,2WKFJ@28221|Deltaproteobacteria,2MJ5I@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Dynamin family	-	-	-	-	-	-	-	-	-	-	-	-	Dynamin_N
k59_5114_1	485913.Krac_3598	3.9e-23	98.6	COG1011@1|root,COG1011@2|Bacteria,2G787@200795|Chloroflexi	200795|Chloroflexi	S	TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3	-	-	3.1.3.10	ko:K07025,ko:K20866	ko00010,ko01120,map00010,map01120	-	R00947	RC00078	ko00000,ko00001,ko01000	-	-	-	HAD_2
k59_112367_1	177437.HRM2_25830	1.6e-67	226.0	COG3850@1|root,COG4191@1|root,COG3850@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42NFY@68525|delta/epsilon subdivisions,2WJKV@28221|Deltaproteobacteria,2MIPK@213118|Desulfobacterales	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_9
k59_172840_1	1382356.JQMP01000004_gene488	6.48e-124	371.0	COG0296@1|root,COG0296@2|Bacteria,2G5IR@200795|Chloroflexi,27XZS@189775|Thermomicrobia	189775|Thermomicrobia	G	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position	glgB	-	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_48
k59_225689_1	1232437.KL662073_gene1743	2.56e-20	87.4	COG1902@1|root,COG1902@2|Bacteria	2|Bacteria	C	pentaerythritol trinitrate reductase activity	-	-	1.3.1.34	ko:K00219	-	-	-	-	ko00000,ko01000	-	-	-	Oxidored_FMN
k59_203349_1	335543.Sfum_2891	4.19e-51	181.0	COG5002@1|root,COG5002@2|Bacteria,1MWF3@1224|Proteobacteria,42NB5@68525|delta/epsilon subdivisions,2WJGX@28221|Deltaproteobacteria,2MQCA@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	Signal transduction histidine kinase	-	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_8,PAS_9,sCache_like
k59_112374_1	439235.Dalk_4515	1.34e-107	329.0	COG3316@1|root,COG3316@2|Bacteria,1RHKZ@1224|Proteobacteria,43CRI@68525|delta/epsilon subdivisions,2X7Z7@28221|Deltaproteobacteria,2MIWI@213118|Desulfobacterales	28221|Deltaproteobacteria	L	PFAM Transposase IS66 family	-	-	-	ko:K07484	-	-	-	-	ko00000	-	-	-	DDE_Tnp_IS66,DDE_Tnp_IS66_C,LZ_Tnp_IS66,zf-IS66
k59_14165_1	933262.AXAM01000015_gene99	1.31e-85	259.0	28P46@1|root,2ZBZF@2|Bacteria,1RAZ9@1224|Proteobacteria,42QY4@68525|delta/epsilon subdivisions,2WN76@28221|Deltaproteobacteria,2MJH3@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Etoposide-induced protein 2.4 (EI24)	-	-	-	ko:K06203	-	-	-	-	ko00000	-	-	-	EI24
k59_189043_1	335543.Sfum_0672	1.42e-14	73.9	COG1361@1|root,COG1361@2|Bacteria	2|Bacteria	M	extracellular matrix structural constituent	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Cohesin,SprB
k59_218616_1	439235.Dalk_0134	5.1e-52	174.0	COG0568@1|root,COG0568@2|Bacteria,1MVWR@1224|Proteobacteria,42NRM@68525|delta/epsilon subdivisions,2WJ0S@28221|Deltaproteobacteria,2MHVP@213118|Desulfobacterales	28221|Deltaproteobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	rpoH	-	-	ko:K03086,ko:K03089	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
k59_226217_1	1236976.JCM16418_377	4.98e-120	354.0	COG0620@1|root,COG0620@2|Bacteria,1TPDQ@1239|Firmicutes,4HADW@91061|Bacilli,26Q9G@186822|Paenibacillaceae	91061|Bacilli	E	Catalyzes the formation of tetrahydropteroyl-L-glutamate and methionine from L-homocysteine and 5-methyltetrahydropteroyltri-L-glutamate	yxjG	-	-	-	-	-	-	-	-	-	-	-	Meth_synt_2
k59_211652_1	335543.Sfum_1404	9.32e-64	214.0	COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,42MQS@68525|delta/epsilon subdivisions,2WINP@28221|Deltaproteobacteria,2MR0I@213462|Syntrophobacterales	28221|Deltaproteobacteria	I	PFAM Enoyl-CoA hydratase isomerase	-	-	1.1.1.35,4.2.1.17,5.1.2.3,5.3.3.8	ko:K01782,ko:K01825	ko00071,ko00280,ko00281,ko00310,ko00362,ko00380,ko00410,ko00640,ko00650,ko00903,ko00930,ko01040,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00071,map00280,map00281,map00310,map00362,map00380,map00410,map00640,map00650,map00903,map00930,map01040,map01100,map01110,map01120,map01130,map01200,map01212	M00032,M00087	R01975,R03026,R03045,R03276,R04137,R04170,R04203,R04204,R04224,R04737,R04738,R04739,R04740,R04741,R04744,R04745,R04746,R04748,R04749,R04756,R05066,R05305,R06411,R06412,R06941,R06942,R07935,R07951,R08093,R08094	RC00029,RC00099,RC00117,RC00241,RC00525,RC00831,RC00834,RC00896,RC01078,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	3HCDH,3HCDH_N,ECH_1
k59_189048_1	335543.Sfum_2526	5.9e-79	244.0	COG1163@1|root,COG1163@2|Bacteria,1RFPD@1224|Proteobacteria,42ZF3@68525|delta/epsilon subdivisions,2WUZY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	TGS domain	-	-	-	ko:K06944	-	-	-	-	ko00000	-	-	-	MMR_HSR1,TGS
k59_28724_1	96561.Dole_1063	1.78e-81	256.0	COG0372@1|root,COG0372@2|Bacteria,1MUKX@1224|Proteobacteria,42N8U@68525|delta/epsilon subdivisions,2WJAN@28221|Deltaproteobacteria,2MHQF@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Belongs to the citrate synthase family	citZ	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt,HTH_17
k59_203785_1	644281.MFS40622_1027	1.38e-51	167.0	COG1943@1|root,arCOG02759@2157|Archaea,2XXEA@28890|Euryarchaeota	28890|Euryarchaeota	L	COG1943 Transposase and inactivated derivatives	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
k59_203785_2	518766.Rmar_2858	1.49e-64	209.0	COG0675@1|root,COG0675@2|Bacteria,4P0KK@976|Bacteroidetes,1FJQR@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	L	Probable transposase	-	-	-	ko:K07496	-	-	-	-	ko00000	-	-	-	OrfB_IS605,OrfB_Zn_ribbon
k59_180513_1	335543.Sfum_0384	1.06e-76	248.0	COG0411@1|root,COG4177@1|root,COG0411@2|Bacteria,COG4177@2|Bacteria,1MUTY@1224|Proteobacteria,42QBI@68525|delta/epsilon subdivisions,2WJWJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01995,ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C,BPD_transp_2
k59_51679_2	1232437.KL661966_gene3136	4.23e-47	160.0	COG2048@1|root,COG2048@2|Bacteria,1N37J@1224|Proteobacteria,42P51@68525|delta/epsilon subdivisions,2WK1J@28221|Deltaproteobacteria,2MKTG@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Cysteine-rich domain	hdrB	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03389	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	CCG
k59_119926_1	909663.KI867150_gene391	6.94e-52	171.0	COG1633@1|root,COG1633@2|Bacteria,1NG4N@1224|Proteobacteria,42W3T@68525|delta/epsilon subdivisions,2WREZ@28221|Deltaproteobacteria,2MRRS@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Rubrerythrin	-	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
k59_97511_1	194439.CT1391	1.04e-48	175.0	COG0038@1|root,COG2239@1|root,COG0038@2|Bacteria,COG2239@2|Bacteria,1FD6C@1090|Chlorobi	1090|Chlorobi	P	PFAM CBS domain containing protein	-	-	-	ko:K03281	-	-	-	-	ko00000	2.A.49	-	-	CBS,Voltage_CLC
k59_66856_1	153948.NAL212_1363	2.74e-86	264.0	COG3677@1|root,COG3677@2|Bacteria,1R3ZS@1224|Proteobacteria,2WFCR@28216|Betaproteobacteria	1224|Proteobacteria	L	Transposase zinc-ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS1595,Zn_Tnp_IS1595
k59_51686_1	1232437.KL661976_gene4970	6.39e-32	125.0	COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,42M88@68525|delta/epsilon subdivisions,2WIZI@28221|Deltaproteobacteria,2MJ2S@213118|Desulfobacterales	28221|Deltaproteobacteria	T	PFAM sigma-54 factor interaction domain-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,PAS_9,Sigma54_activat
k59_173342_2	472759.Nhal_3385	3.38e-08	59.7	COG0859@1|root,COG0859@2|Bacteria,1MYZA@1224|Proteobacteria,1RPMN@1236|Gammaproteobacteria,1WVVR@135613|Chromatiales	135613|Chromatiales	M	PFAM glycosyl transferase family 9	-	-	-	ko:K02841	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
k59_51694_1	929556.Solca_1449	2.45e-06	52.8	COG4339@1|root,COG4339@2|Bacteria,4PKIS@976|Bacteroidetes,1J0HU@117747|Sphingobacteriia	976|Bacteroidetes	S	SMART Metal-dependent phosphohydrolase, HD region	-	-	-	-	-	-	-	-	-	-	-	-	HD
k59_66871_2	247490.KSU1_D0452	5.97e-27	111.0	COG0859@1|root,COG0859@2|Bacteria,2J4DC@203682|Planctomycetes	203682|Planctomycetes	M	Glycosyltransferase family 9 (heptosyltransferase)	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_9
k59_203808_1	748449.Halha_0880	3.24e-68	230.0	COG1198@1|root,COG1198@2|Bacteria,1TNYB@1239|Firmicutes,248EI@186801|Clostridia,3WACI@53433|Halanaerobiales	186801|Clostridia	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,ResIII
k59_173355_1	335543.Sfum_4076	4.02e-26	101.0	COG1014@1|root,COG1014@2|Bacteria,1RBZA@1224|Proteobacteria,42QT3@68525|delta/epsilon subdivisions,2X6H9@28221|Deltaproteobacteria,2MS04@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	PFAM pyruvate ferredoxin flavodoxin oxidoreductase	-	-	1.2.7.8	ko:K00180	-	-	-	-	br01601,ko00000,ko01000	-	-	-	POR
k59_218640_1	1499967.BAYZ01000155_gene659	5.96e-51	185.0	COG3829@1|root,COG4251@1|root,COG3829@2|Bacteria,COG4251@2|Bacteria,2NR7U@2323|unclassified Bacteria	2|Bacteria	T	PAS fold	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,HisKA_3,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
k59_66881_1	313606.M23134_06185	1.49e-17	85.1	COG5433@1|root,COG5433@2|Bacteria,4NUMH@976|Bacteroidetes,47SE2@768503|Cytophagia	976|Bacteroidetes	L	transposase activity	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_assoc
k59_105395_1	1265505.ATUG01000003_gene21	2.86e-36	129.0	COG2259@1|root,COG2259@2|Bacteria,1NPDG@1224|Proteobacteria,42TWF@68525|delta/epsilon subdivisions,2WQ14@28221|Deltaproteobacteria,2MKQD@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Methylamine utilisation protein MauE	-	-	-	-	-	-	-	-	-	-	-	-	MauE
k59_89994_1	880072.Desac_0834	4.11e-190	558.0	COG1145@1|root,COG1148@1|root,COG1145@2|Bacteria,COG1148@2|Bacteria,1QUM4@1224|Proteobacteria,42MPP@68525|delta/epsilon subdivisions,2WJ3U@28221|Deltaproteobacteria,2MQVU@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	4Fe-4S ferredoxin iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_20,Pyr_redox_2
k59_66885_1	273068.TTE0537	2.67e-14	73.2	COG0454@1|root,COG0456@2|Bacteria,1V6KU@1239|Firmicutes,24J9Z@186801|Clostridia,42G5T@68295|Thermoanaerobacterales	186801|Clostridia	K	This enzyme acetylates the N-terminal alanine of ribosomal protein S18	rimI	-	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1,Acetyltransf_10
k59_241308_1	269799.Gmet_0034	2.9e-49	170.0	COG1408@1|root,COG1408@2|Bacteria,1MUH5@1224|Proteobacteria,42N75@68525|delta/epsilon subdivisions,2WKJY@28221|Deltaproteobacteria,43SDV@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Calcineurin-like phosphoesterase	-	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	Metallophos
k59_189074_1	1322246.BN4_10033	7.69e-96	289.0	COG0444@1|root,COG0444@2|Bacteria,1R4KB@1224|Proteobacteria,42M3F@68525|delta/epsilon subdivisions,2WJ32@28221|Deltaproteobacteria,2M7V3@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	Belongs to the ABC transporter superfamily	oppD	-	-	ko:K02031,ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
k59_189074_2	177439.DP0151	3.01e-24	100.0	COG4608@1|root,COG4608@2|Bacteria,1NU4K@1224|Proteobacteria,42TDH@68525|delta/epsilon subdivisions,2WIQT@28221|Deltaproteobacteria,2MI06@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Belongs to the ABC transporter superfamily	-	-	-	ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
k59_28762_1	1265505.ATUG01000001_gene3026	4.68e-33	127.0	COG0493@1|root,COG1148@1|root,COG0493@2|Bacteria,COG1148@2|Bacteria,1MU2H@1224|Proteobacteria,42M6X@68525|delta/epsilon subdivisions,2X6YD@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_20,Pyr_redox_2
k59_28762_2	1232437.KL662061_gene4184	6.19e-89	265.0	COG0247@1|root,COG0247@2|Bacteria,1NTE3@1224|Proteobacteria,42Z1T@68525|delta/epsilon subdivisions,2WUIQ@28221|Deltaproteobacteria,2MN6B@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Cysteine-rich domain	-	-	-	-	-	-	-	-	-	-	-	-	CCG
k59_82660_2	1123242.JH636434_gene5030	5.02e-07	54.7	COG2204@1|root,COG2204@2|Bacteria,2IY95@203682|Planctomycetes	203682|Planctomycetes	T	COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
k59_165361_1	113395.AXAI01000021_gene3452	5.46e-37	140.0	COG0745@1|root,COG0784@1|root,COG2203@1|root,COG4191@1|root,COG0745@2|Bacteria,COG0784@2|Bacteria,COG2203@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2TR8X@28211|Alphaproteobacteria,3JV46@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Response_reg
k59_135935_1	33035.JPJF01000001_gene2548	2.82e-23	105.0	COG0209@1|root,COG0209@2|Bacteria,1TPFH@1239|Firmicutes,249EN@186801|Clostridia,3Y12B@572511|Blautia	186801|Clostridia	F	Ribonucleotide reductase, barrel domain	-	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	ATP-cone,Ribonuc_red_lgC
k59_82663_1	886293.Sinac_7397	2.41e-41	150.0	COG1861@1|root,COG1861@2|Bacteria,2J3F7@203682|Planctomycetes	203682|Planctomycetes	M	PFAM Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_4
k59_143511_1	96561.Dole_0493	1.2e-47	169.0	COG3233@1|root,COG3233@2|Bacteria,1RB7V@1224|Proteobacteria,42RBC@68525|delta/epsilon subdivisions,2WMQB@28221|Deltaproteobacteria,2MJK1@213118|Desulfobacterales	28221|Deltaproteobacteria	S	deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_37130_1	1120934.KB894459_gene1371	1.85e-14	77.8	2DR6Y@1|root,33AFQ@2|Bacteria,2I8DZ@201174|Actinobacteria	201174|Actinobacteria	S	RNA ligase	-	-	6.5.1.3	ko:K14680	-	-	-	-	ko00000,ko01000	-	-	-	RNA_lig_T4_1
k59_207370_2	933262.AXAM01000001_gene353	1.67e-40	144.0	COG0329@1|root,COG0329@2|Bacteria,1MUCM@1224|Proteobacteria,42M0X@68525|delta/epsilon subdivisions,2WK4D@28221|Deltaproteobacteria,2MHXX@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
k59_63337_1	997346.HMPREF9374_3275	1.39e-35	131.0	COG1062@1|root,COG1062@2|Bacteria,1TP8E@1239|Firmicutes,4HAH9@91061|Bacilli	91061|Bacilli	C	alcohol dehydrogenase	adhC	-	1.1.1.90	ko:K00055	ko00350,ko00360,ko00622,ko00623,ko01100,ko01120,ko01220,map00350,map00360,map00622,map00623,map01100,map01120,map01220	M00537,M00538	R01763,R02611,R04304,R05282,R05347,R05348	RC00087,RC00116	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N
k59_184684_2	215803.DB30_0959	5.4e-05	49.7	COG1716@1|root,COG2114@1|root,COG2203@1|root,COG1716@2|Bacteria,COG2114@2|Bacteria,COG2203@2|Bacteria,1RAHZ@1224|Proteobacteria,42UGY@68525|delta/epsilon subdivisions,2WQPI@28221|Deltaproteobacteria,2YUJD@29|Myxococcales	28221|Deltaproteobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	FHA,GAF,GAF_2,Guanylate_cyc
k59_161906_1	335543.Sfum_2401	1.88e-47	172.0	COG0784@1|root,COG3829@1|root,COG4191@1|root,COG0784@2|Bacteria,COG3829@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MC4@68525|delta/epsilon subdivisions,2WIZU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,PocR,Response_reg,dCache_1
k59_63775_1	1232437.KL662042_gene2028	1.98e-23	93.6	COG0328@1|root,COG0328@2|Bacteria,1RI5K@1224|Proteobacteria,42T01@68525|delta/epsilon subdivisions,2WPRB@28221|Deltaproteobacteria,2MNEJ@213118|Desulfobacterales	28221|Deltaproteobacteria	L	RNase H	-	-	-	-	-	-	-	-	-	-	-	-	RNase_H
k59_63775_2	879212.DespoDRAFT_02386	3.29e-18	84.3	COG2357@1|root,COG2357@2|Bacteria,1RCHE@1224|Proteobacteria,42PPK@68525|delta/epsilon subdivisions,2WJBS@28221|Deltaproteobacteria,2MHSG@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Region found in RelA / SpoT proteins	-	-	-	-	-	-	-	-	-	-	-	-	RelA_SpoT
k59_124696_1	1121403.AUCV01000001_gene674	1.95e-69	224.0	COG1492@1|root,COG1492@2|Bacteria,1MUFY@1224|Proteobacteria,42M9K@68525|delta/epsilon subdivisions,2WJ22@28221|Deltaproteobacteria,2MI02@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation	cobQ	-	6.3.5.10	ko:K02232	ko00860,ko01100,map00860,map01100	M00122	R05225	RC00010,RC01302	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_26,Aminotran_1_2,CbiA,GATase_3,TP_methylase
k59_139675_1	338963.Pcar_1079	7.88e-18	80.5	COG0599@1|root,COG0599@2|Bacteria,1QTZH@1224|Proteobacteria,42TJW@68525|delta/epsilon subdivisions,2X5P7@28221|Deltaproteobacteria,43UQ2@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Carboxymuconolactone decarboxylase family	-	-	-	-	-	-	-	-	-	-	-	-	CMD
k59_139675_2	269797.Mbar_A0765	1.43e-45	157.0	COG4925@1|root,arCOG06704@2157|Archaea,2XY6I@28890|Euryarchaeota,2NB4J@224756|Methanomicrobia	224756|Methanomicrobia	I	sulfurtransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_139675_3	527002.yaldo0001_1670	1.15e-60	196.0	COG0667@1|root,COG0667@2|Bacteria,1MVEH@1224|Proteobacteria,1RPX5@1236|Gammaproteobacteria,41EUQ@629|Yersinia	1236|Gammaproteobacteria	C	aldo keto reductase	iolS	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
k59_192548_1	452637.Oter_0946	1.59e-25	109.0	COG4251@1|root,COG5278@1|root,COG4251@2|Bacteria,COG5278@2|Bacteria,46U7H@74201|Verrucomicrobia	74201|Verrucomicrobia	T	PFAM ATP-binding region ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,HATPase_c,HisKA
k59_154885_1	1121396.KB893077_gene740	6.37e-112	328.0	COG2152@1|root,COG2152@2|Bacteria,1MX8M@1224|Proteobacteria,42QDF@68525|delta/epsilon subdivisions,2WMG5@28221|Deltaproteobacteria,2MJJI@213118|Desulfobacterales	28221|Deltaproteobacteria	G	beta-1,4-mannooligosaccharide phosphorylase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_130
k59_109017_2	525897.Dbac_3138	1.07e-09	60.1	COG0310@1|root,COG0310@2|Bacteria,1RJRC@1224|Proteobacteria,42QZ5@68525|delta/epsilon subdivisions,2WMQX@28221|Deltaproteobacteria,2MB0Q@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	PFAM cobalamin (vitamin B12) biosynthesis CbiM	cbiM	-	-	ko:K02007	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	CbiM
k59_48417_1	589865.DaAHT2_1636	9.45e-103	313.0	COG0034@1|root,COG0034@2|Bacteria,1MU0V@1224|Proteobacteria,42MDB@68525|delta/epsilon subdivisions,2WITV@28221|Deltaproteobacteria,2MI1E@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_6,GATase_7,Pribosyltran
k59_2820_1	385682.AFSL01000088_gene852	1.33e-23	102.0	COG3547@1|root,COG3547@2|Bacteria,4NJ8G@976|Bacteroidetes,2FRWC@200643|Bacteroidia	976|Bacteroidetes	L	COG COG3547 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_146962_2	338963.Pcar_2450	1.47e-43	157.0	COG1048@1|root,COG1048@2|Bacteria,1MU9T@1224|Proteobacteria,42N5M@68525|delta/epsilon subdivisions,2WIIV@28221|Deltaproteobacteria,43RYP@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Aconitase C-terminal domain	-	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2763	Aconitase,Aconitase_C
k59_79034_1	933262.AXAM01000033_gene1644	1.54e-122	363.0	COG2069@1|root,COG2069@2|Bacteria,1QS8G@1224|Proteobacteria,437H2@68525|delta/epsilon subdivisions,2WKVX@28221|Deltaproteobacteria,2MI1T@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM CO dehydrogenase acetyl-CoA synthase delta subunit	-	-	2.1.1.245	ko:K00194	ko00680,ko00720,ko01120,ko01200,map00680,map00720,map01120,map01200	M00357,M00377,M00422	R09096,R10219,R10243	RC00004,RC00113,RC02977	ko00000,ko00001,ko00002,ko01000	-	-	-	CdhD
k59_207972_2	56780.SYN_01904	3.59e-15	74.7	COG0464@1|root,COG0464@2|Bacteria,1QFHD@1224|Proteobacteria,42QEP@68525|delta/epsilon subdivisions,2WIT4@28221|Deltaproteobacteria,2MQYB@213462|Syntrophobacterales	28221|Deltaproteobacteria	O	ATPase family associated with various cellular activities (AAA)	-	-	-	-	-	-	-	-	-	-	-	-	AAA,DUF4032
k59_116531_1	439235.Dalk_5070	4.24e-105	322.0	COG3829@1|root,COG4191@1|root,COG3829@2|Bacteria,COG4191@2|Bacteria,1R682@1224|Proteobacteria,42P91@68525|delta/epsilon subdivisions,2WKQI@28221|Deltaproteobacteria,2MJEK@213118|Desulfobacterales	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4,PAS_9
k59_185427_1	1121405.dsmv_0373	2.48e-20	89.7	COG0593@1|root,COG0593@2|Bacteria,1MU5H@1224|Proteobacteria,42MA0@68525|delta/epsilon subdivisions,2WJAT@28221|Deltaproteobacteria,2MHNX@213118|Desulfobacterales	28221|Deltaproteobacteria	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	-	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
k59_185427_3	1304885.AUEY01000110_gene2944	6.61e-12	64.7	COG0483@1|root,COG0483@2|Bacteria,1MUQT@1224|Proteobacteria,42R1W@68525|delta/epsilon subdivisions,2WMQ4@28221|Deltaproteobacteria,2MJPN@213118|Desulfobacterales	28221|Deltaproteobacteria	G	PFAM Inositol monophosphatase	suhB	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
k59_56273_1	439235.Dalk_1166	1.28e-14	79.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42N0F@68525|delta/epsilon subdivisions,2WJAE@28221|Deltaproteobacteria,2MIUP@213118|Desulfobacterales	28221|Deltaproteobacteria	NT	PFAM chemotaxis sensory transducer	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CZB,HAMP,MCPsignal
k59_223109_1	1265505.ATUG01000002_gene2326	7.71e-18	75.1	2ET10@1|root,33KJ8@2|Bacteria,1NM0I@1224|Proteobacteria,42XRS@68525|delta/epsilon subdivisions,2WTDQ@28221|Deltaproteobacteria,2MMCN@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_63803_1	1183438.GKIL_2514	1.67e-44	160.0	COG0141@1|root,COG0141@2|Bacteria,1G1I2@1117|Cyanobacteria	1117|Cyanobacteria	E	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine	hisD	GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.23	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01158,R01163,R03012	RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000	-	-	-	Histidinol_dh
k59_230633_1	439235.Dalk_0979	1.97e-18	83.2	2C8BN@1|root,32RKS@2|Bacteria,1N7Z0@1224|Proteobacteria,42WEU@68525|delta/epsilon subdivisions,2WS8J@28221|Deltaproteobacteria,2MP0X@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Glycine-zipper domain	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_86251_1	335543.Sfum_1697	4.65e-82	249.0	COG2220@1|root,COG2220@2|Bacteria,1QB9E@1224|Proteobacteria,42N7W@68525|delta/epsilon subdivisions,2WNMC@28221|Deltaproteobacteria,2MQPI@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_3
k59_124728_1	1229909.NSED_04875	1.11e-41	152.0	COG0017@1|root,arCOG00406@2157|Archaea,41SBT@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)	-	-	6.1.1.23	ko:K09759	ko00970,map00970	M00360	R03647,R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
k59_139701_1	1298867.AUES01000008_gene5163	1.77e-98	295.0	COG0620@1|root,COG0620@2|Bacteria	2|Bacteria	E	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation	xecA1	-	2.1.1.14,4.4.1.23	ko:K00549,ko:K22363	ko00270,ko00450,ko00625,ko01100,ko01110,ko01230,map00270,map00450,map00625,map01100,map01110,map01230	M00017	R04405,R09365,R11897,R11899	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	Meth_synt_2
k59_132014_2	287.DR97_3736	4.86e-67	215.0	COG4397@1|root,COG4397@2|Bacteria,1MWX8@1224|Proteobacteria,1RR4A@1236|Gammaproteobacteria,1YHJA@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	S	Mu-like prophage major head subunit gpT	-	-	-	-	-	-	-	-	-	-	-	-	Mu-like_gpT
k59_63807_1	1265505.ATUG01000001_gene4261	1.65e-40	149.0	COG1185@1|root,COG1185@2|Bacteria,1MVB9@1224|Proteobacteria,42MTZ@68525|delta/epsilon subdivisions,2WJCE@28221|Deltaproteobacteria,2MIS9@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004654,GO:0005488,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
k59_63807_2	1304885.AUEY01000003_gene539	6.6e-77	243.0	COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,42P7N@68525|delta/epsilon subdivisions,2WJKE@28221|Deltaproteobacteria,2MICX@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Insulinase (Peptidase family M16)	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
k59_238170_1	1235835.C814_00118	2.36e-21	92.0	COG0546@1|root,COG0546@2|Bacteria,1V3YI@1239|Firmicutes,24CRF@186801|Clostridia,3WRHJ@541000|Ruminococcaceae	186801|Clostridia	K	HAD-hyrolase-like	gph	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
k59_101896_1	690850.Desaf_3306	3.64e-45	154.0	COG3293@1|root,COG3293@2|Bacteria,1R5NV@1224|Proteobacteria,430FR@68525|delta/epsilon subdivisions,2WVKI@28221|Deltaproteobacteria,2MFEK@213115|Desulfovibrionales	28221|Deltaproteobacteria	L	manually curated	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_2,DUF4096
k59_139706_2	316067.Geob_0785	9.09e-54	180.0	COG0849@1|root,COG0849@2|Bacteria,1MUSR@1224|Proteobacteria,42MS2@68525|delta/epsilon subdivisions,2WIQ0@28221|Deltaproteobacteria,43SXW@69541|Desulfuromonadales	28221|Deltaproteobacteria	D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring	ftsA	-	-	ko:K03590	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036,ko04812	-	-	-	FtsA,SHS2_FTSA
k59_33380_1	1121405.dsmv_2690	6.91e-67	205.0	COG0599@1|root,COG0599@2|Bacteria,1Q5KF@1224|Proteobacteria,42SAS@68525|delta/epsilon subdivisions,2WP9N@28221|Deltaproteobacteria,2MKBW@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Carboxymuconolactone decarboxylase family	-	-	4.1.1.44	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	-	R03470	RC00938	ko00000,ko00001,ko01000	-	-	-	CMD
k59_33380_2	1232437.KL661961_gene3023	9.33e-33	122.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,42NHU@68525|delta/epsilon subdivisions,2WIZ1@28221|Deltaproteobacteria,2MIQ6@213118|Desulfobacterales	28221|Deltaproteobacteria	I	acyl-CoA dehydrogenase	-	-	1.3.99.32	ko:K16173	ko00362,ko01120,map00362,map01120	-	R05579	RC00052	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
k59_94028_1	1504672.669787022	4.33e-16	73.9	COG3335@1|root,COG3335@2|Bacteria,1N2V9@1224|Proteobacteria,2VRMI@28216|Betaproteobacteria	1224|Proteobacteria	L	Homeodomain-like domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_32
k59_94028_2	555779.Dthio_PD2189	2.09e-124	358.0	COG3335@1|root,COG3335@2|Bacteria,1N5WI@1224|Proteobacteria,42R7X@68525|delta/epsilon subdivisions,2WQV8@28221|Deltaproteobacteria,2MEUM@213115|Desulfovibrionales	28221|Deltaproteobacteria	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3
k59_124741_1	56780.SYN_00987	9.7e-12	61.2	COG0089@1|root,COG0089@2|Bacteria,1MZXX@1224|Proteobacteria,42V3Y@68525|delta/epsilon subdivisions,2WRMX@28221|Deltaproteobacteria,2MQN2@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome	rplW	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02892	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L23
k59_124741_2	177439.DP1125	4.96e-74	229.0	COG0088@1|root,COG0088@2|Bacteria,1MXPF@1224|Proteobacteria,42MPW@68525|delta/epsilon subdivisions,2WN96@28221|Deltaproteobacteria,2MJHZ@213118|Desulfobacterales	28221|Deltaproteobacteria	J	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome	rplD	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02926	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L4
k59_124741_3	589865.DaAHT2_1452	2.8e-69	217.0	COG0087@1|root,COG0087@2|Bacteria,1MUST@1224|Proteobacteria,42NV2@68525|delta/epsilon subdivisions,2WNJ1@28221|Deltaproteobacteria,2MJKX@213118|Desulfobacterales	28221|Deltaproteobacteria	J	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit	rplC	-	-	ko:K02906	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L3
k59_124741_4	439235.Dalk_1916	3.38e-46	150.0	COG0051@1|root,COG0051@2|Bacteria,1RGWF@1224|Proteobacteria,42SE4@68525|delta/epsilon subdivisions,2WP4K@28221|Deltaproteobacteria,2MK4M@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Involved in the binding of tRNA to the ribosomes	rpsJ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02946	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S10
k59_10671_1	1121405.dsmv_3234	1.8e-90	285.0	COG0143@1|root,COG0143@2|Bacteria,1MUBY@1224|Proteobacteria,42N1K@68525|delta/epsilon subdivisions,2WIT6@28221|Deltaproteobacteria,2MHP4@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	-	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g,tRNA_bind
k59_79043_1	96561.Dole_2658	1.8e-72	227.0	COG1092@1|root,COG1092@2|Bacteria,1QW1V@1224|Proteobacteria,42Q3P@68525|delta/epsilon subdivisions,2WJXM@28221|Deltaproteobacteria,2MHVR@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Belongs to the methyltransferase superfamily	-	-	2.1.1.173,2.1.1.191,2.1.1.264	ko:K06969,ko:K12297	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
k59_71193_1	589865.DaAHT2_2126	1.63e-40	139.0	COG1607@1|root,COG1607@2|Bacteria,1RAEQ@1224|Proteobacteria,42SPA@68525|delta/epsilon subdivisions,2WPPE@28221|Deltaproteobacteria,2MJW0@213118|Desulfobacterales	28221|Deltaproteobacteria	I	Thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
k59_169798_1	1121405.dsmv_0320	5.42e-68	223.0	COG0644@1|root,COG2440@1|root,COG0644@2|Bacteria,COG2440@2|Bacteria,1MVU6@1224|Proteobacteria,42PTE@68525|delta/epsilon subdivisions,2WKRZ@28221|Deltaproteobacteria,2MIH0@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Electron transfer flavoprotein-ubiquinone oxidoreductase	-	-	1.5.5.1	ko:K00311	-	-	-	-	ko00000,ko01000	-	-	-	ETF_QO
k59_208016_1	118168.MC7420_4451	4.47e-24	108.0	COG2199@1|root,COG2202@1|root,COG3829@1|root,COG3850@1|root,COG4191@1|root,COG4251@1|root,COG5002@1|root,COG2202@2|Bacteria,COG3706@2|Bacteria,COG3829@2|Bacteria,COG3850@2|Bacteria,COG4191@2|Bacteria,COG4251@2|Bacteria,COG5002@2|Bacteria,1GHCI@1117|Cyanobacteria,1HHXQ@1150|Oscillatoriales	1117|Cyanobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,GAF,HAMP,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg,dCache_1
k59_238185_1	1232437.KL662048_gene5098	1.16e-58	194.0	COG0674@1|root,COG0674@2|Bacteria,1R4K0@1224|Proteobacteria,42NQJ@68525|delta/epsilon subdivisions,2WJ0K@28221|Deltaproteobacteria,2MIND@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Pyruvate:ferredoxin oxidoreductase core domain II	-	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR_N
k59_18082_1	96561.Dole_1949	4.75e-22	96.7	COG0128@1|root,COG0128@2|Bacteria,1MWMK@1224|Proteobacteria,42N01@68525|delta/epsilon subdivisions,2WKJQ@28221|Deltaproteobacteria,2MI6K@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	aroA	-	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	EPSP_synthase
k59_33404_1	335543.Sfum_3097	1.2e-85	277.0	COG2937@1|root,COG2937@2|Bacteria,1MWZ6@1224|Proteobacteria,42MN4@68525|delta/epsilon subdivisions,2WJJ5@28221|Deltaproteobacteria,2MR0U@213462|Syntrophobacterales	28221|Deltaproteobacteria	I	Belongs to the GPAT DAPAT family	plsB	-	2.3.1.15	ko:K00631	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
k59_124744_1	335543.Sfum_2525	4.25e-101	307.0	COG0568@1|root,COG0568@2|Bacteria,1MXGX@1224|Proteobacteria,42PIS@68525|delta/epsilon subdivisions,2WKSS@28221|Deltaproteobacteria,2MQYD@213462|Syntrophobacterales	28221|Deltaproteobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	-	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
k59_109067_1	1408823.AXUS01000006_gene44	7.7e-29	119.0	COG1249@1|root,COG1249@2|Bacteria,1TP1W@1239|Firmicutes,249R3@186801|Clostridia,25RJ2@186804|Peptostreptococcaceae	186801|Clostridia	C	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain	lpdA	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
k59_33411_1	1121405.dsmv_2419	2.22e-08	56.2	COG0715@1|root,COG0715@2|Bacteria,1PEB1@1224|Proteobacteria,42PTA@68525|delta/epsilon subdivisions,2WM25@28221|Deltaproteobacteria,2MIGF@213118|Desulfobacterales	28221|Deltaproteobacteria	P	NMT1/THI5 like	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1
k59_33411_2	1121405.dsmv_2418	2.94e-34	124.0	COG0600@1|root,COG0600@2|Bacteria,1NDW4@1224|Proteobacteria,42PPI@68525|delta/epsilon subdivisions,2WMA3@28221|Deltaproteobacteria,2MI72@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02050	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	BPD_transp_1
k59_177447_1	1121405.dsmv_1977	3.44e-70	226.0	COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,42M88@68525|delta/epsilon subdivisions,2WIZI@28221|Deltaproteobacteria,2MJ2S@213118|Desulfobacterales	28221|Deltaproteobacteria	T	PFAM sigma-54 factor interaction domain-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,PAS_9,Sigma54_activat
k59_79057_1	1121403.AUCV01000051_gene2131	4.61e-68	230.0	COG3264@1|root,COG3264@2|Bacteria,1MWSA@1224|Proteobacteria,42N78@68525|delta/epsilon subdivisions,2WM0M@28221|Deltaproteobacteria,2MHVS@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Mechanosensitive ion channel	-	-	-	ko:K05802	-	-	-	-	ko00000,ko02000	1.A.23.1.1	-	-	MS_channel
k59_139726_1	323259.Mhun_0486	3.36e-24	106.0	COG1404@1|root,arCOG00702@2157|Archaea,2XUT1@28890|Euryarchaeota,2NBHB@224756|Methanomicrobia	28890|Euryarchaeota	O	Subtilase family	hly	GO:0005575,GO:0005576	-	ko:K14645	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	PKD,Peptidase_S8,TAT_signal
k59_86287_1	1094980.Mpsy_1741	9.3e-69	218.0	COG1045@1|root,arCOG01847@2157|Archaea,2XUZJ@28890|Euryarchaeota,2N9VY@224756|Methanomicrobia	224756|Methanomicrobia	E	TIGRFAM serine O-acetyltransferase	-	-	2.3.1.30	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	M00021	R00586	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	FeS_assembly_P,Hexapep,SATase_N
k59_177448_1	331678.Cphamn1_1830	7.98e-30	110.0	COG2044@1|root,COG2044@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K06039,ko:K07092	-	-	-	-	ko00000	-	-	-	DrsE
k59_10705_1	411476.BACOVA_03925	4.15e-26	110.0	COG1783@1|root,COG1783@2|Bacteria,4NSQV@976|Bacteroidetes,2G22K@200643|Bacteroidia,4AKTX@815|Bacteroidaceae	976|Bacteroidetes	S	Phage terminase large subunit	-	-	-	ko:K06909	-	-	-	-	ko00000	-	-	-	Terminase_3
k59_40980_1	706587.Desti_3540	6.58e-42	147.0	COG1600@1|root,COG1600@2|Bacteria,1RAYI@1224|Proteobacteria,42R4W@68525|delta/epsilon subdivisions,2WK0B@28221|Deltaproteobacteria,2MSDE@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_169812_1	706587.Desti_1742	6.36e-103	312.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WJF9@28221|Deltaproteobacteria,2MR5I@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	PFAM response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
k59_208034_1	1121920.AUAU01000014_gene2832	1e-25	111.0	COG1652@1|root,COG1652@2|Bacteria	2|Bacteria	S	positive regulation of growth rate	-	-	-	-	-	-	-	-	-	-	-	-	CW_binding_2,LysM
k59_162356_1	498761.HM1_3125	3.24e-09	58.5	2DSV3@1|root,33HII@2|Bacteria,1VQ64@1239|Firmicutes,24VWA@186801|Clostridia	186801|Clostridia	S	ORF located using Blastx	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_205947_1	1121405.dsmv_1703	5.16e-68	229.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,42NAV@68525|delta/epsilon subdivisions,2WJ3W@28221|Deltaproteobacteria,2MIIB@213118|Desulfobacterales	28221|Deltaproteobacteria	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
k59_167835_1	335543.Sfum_0929	6.22e-66	224.0	COG0587@1|root,COG0587@2|Bacteria,1MUIF@1224|Proteobacteria,42MGP@68525|delta/epsilon subdivisions,2WIZ2@28221|Deltaproteobacteria,2MQUW@213462|Syntrophobacterales	28221|Deltaproteobacteria	L	DNA polymerase III alpha subunit	-	-	2.7.7.7	ko:K02337,ko:K14162	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
k59_99730_1	335543.Sfum_0155	6.12e-95	285.0	COG1774@1|root,COG1774@2|Bacteria,1MZBX@1224|Proteobacteria,42NE3@68525|delta/epsilon subdivisions,2WK98@28221|Deltaproteobacteria,2MQEI@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	PSP1 C-terminal conserved region	-	-	-	-	-	-	-	-	-	-	-	-	PSP1
k59_46671_1	243090.RB1661	1.59e-43	162.0	COG2911@1|root,COG2911@2|Bacteria	2|Bacteria	S	protein secretion	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Cadherin,Cadherin_3,Calx-beta,DUF4347,He_PIG,Invasin_D3,Laminin_G_3,Lectin_C,PA14,Pentaxin,Peptidase_S74
k59_8744_1	1463825.JNXC01000003_gene3834	9.2e-26	105.0	COG0110@1|root,COG0110@2|Bacteria,2GKZ4@201174|Actinobacteria,4E1D3@85010|Pseudonocardiales	201174|Actinobacteria	S	Bacterial transferase hexapeptide (six repeats)	-	-	-	ko:K18234	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	Hexapep
k59_175575_1	177439.DP2993	1.79e-40	152.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42MXI@68525|delta/epsilon subdivisions,2X5DH@28221|Deltaproteobacteria,2MQ31@213118|Desulfobacterales	68525|delta/epsilon subdivisions	NT	helical bimodular (HBM) domain	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,Cache_3-Cache_2,HAMP,MCPsignal,PAS_3,dCache_1
k59_31517_1	869213.JCM21142_31000	1.91e-05	45.8	COG0205@1|root,COG0205@2|Bacteria,4NFPT@976|Bacteroidetes	976|Bacteroidetes	G	Phosphofructokinase	-	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
k59_221174_1	1304885.AUEY01000044_gene226	8.32e-77	235.0	COG2197@1|root,COG2197@2|Bacteria,1MWGM@1224|Proteobacteria,42Q40@68525|delta/epsilon subdivisions,2WKYI@28221|Deltaproteobacteria,2MJHB@213118|Desulfobacterales	28221|Deltaproteobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	ko:K02479	-	-	-	-	ko00000,ko02022	-	-	-	GerE,Response_reg
k59_92136_1	667014.Thein_0412	5.57e-17	81.6	COG2204@1|root,COG2204@2|Bacteria,2GI78@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	T	AAA domain (Cdc48 subfamily)	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
k59_46676_1	177437.HRM2_08140	4.35e-120	363.0	COG2202@1|root,COG2208@1|root,COG3290@1|root,COG2202@2|Bacteria,COG2208@2|Bacteria,COG3290@2|Bacteria,1RCHY@1224|Proteobacteria,42R1G@68525|delta/epsilon subdivisions,2WMR7@28221|Deltaproteobacteria,2MJNU@213118|Desulfobacterales	28221|Deltaproteobacteria	T	protein phosphatase 2C domain protein	rsbP	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	PAS,PAS_3,PAS_9,SpoIIE
k59_77168_1	1173025.GEI7407_2343	4.04e-38	147.0	COG2217@1|root,COG2217@2|Bacteria,1G0JR@1117|Cyanobacteria,1H9J4@1150|Oscillatoriales	1117|Cyanobacteria	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	pacS	GO:0000041,GO:0003674,GO:0005488,GO:0005507,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006825,GO:0008150,GO:0015677,GO:0016020,GO:0030001,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0046914,GO:0051179,GO:0051234,GO:0071944	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
k59_39136_1	589865.DaAHT2_0507	3.35e-114	343.0	COG0008@1|root,COG1384@1|root,COG0008@2|Bacteria,COG1384@2|Bacteria,1MUCR@1224|Proteobacteria,42MAI@68525|delta/epsilon subdivisions,2WJ8M@28221|Deltaproteobacteria,2MHXE@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
k59_213420_1	330214.NIDE2454	1.52e-87	273.0	COG0114@1|root,COG0114@2|Bacteria,3J0FU@40117|Nitrospirae	40117|Nitrospirae	C	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate	fumC	-	4.2.1.2	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	M00009,M00011,M00173,M00376	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	FumaraseC_C,Lyase_1
k59_190629_1	1304888.ATWF01000001_gene2411	3.13e-20	95.5	COG0751@1|root,COG0751@2|Bacteria,2GF2Q@200930|Deferribacteres	200930|Deferribacteres	J	Glycyl-tRNA synthetase beta subunit	glyS	-	6.1.1.14	ko:K01879	ko00970,map00970	M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_1,tRNA_synt_2f
k59_175589_1	706587.Desti_3693	5.79e-82	263.0	COG1022@1|root,COG1022@2|Bacteria,1MU4D@1224|Proteobacteria,42N2G@68525|delta/epsilon subdivisions,2WIXB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	PFAM AMP-dependent synthetase and ligase	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
k59_39143_1	1118054.CAGW01000083_gene2911	0.000234	47.4	COG2204@1|root,COG2204@2|Bacteria,1VSKG@1239|Firmicutes,4HCST@91061|Bacilli,26SMB@186822|Paenibacillaceae	91061|Bacilli	T	Sigma-54 interaction domain	-	-	-	ko:K07714	ko02020,map02020	M00500	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
k59_8758_1	485916.Dtox_1443	4.86e-07	56.6	COG0535@1|root,COG0535@2|Bacteria,1VD3I@1239|Firmicutes,25CAI@186801|Clostridia	186801|Clostridia	C	4Fe-4S single cluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM
k59_31524_1	880072.Desac_0689	1.94e-80	258.0	COG1154@1|root,COG1154@2|Bacteria,1MUSJ@1224|Proteobacteria,42M35@68525|delta/epsilon subdivisions,2WIX5@28221|Deltaproteobacteria,2MQAA@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)	dxs	-	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	-	DXP_synthase_N,Transket_pyr,Transketolase_C
k59_92154_1	335543.Sfum_2467	1.69e-39	136.0	COG5496@1|root,COG5496@2|Bacteria,1RKFT@1224|Proteobacteria,434CW@68525|delta/epsilon subdivisions,2X34J@28221|Deltaproteobacteria,2MRVR@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Thioesterase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_92156_1	555079.Toce_0451	1.38e-23	99.8	COG1013@1|root,COG1013@2|Bacteria,1TPF0@1239|Firmicutes,24BE5@186801|Clostridia,42HZF@68295|Thermoanaerobacterales	186801|Clostridia	C	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain	-	GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016054,GO:0016491,GO:0016625,GO:0016903,GO:0019752,GO:0033609,GO:0033611,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:1901575	1.2.7.1,1.2.7.10	ko:K00170,ko:K19071	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
k59_39157_1	56780.SYN_01742	2.13e-57	196.0	COG0770@1|root,COG0770@2|Bacteria,1QTSF@1224|Proteobacteria,42MXF@68525|delta/epsilon subdivisions,2WIJZ@28221|Deltaproteobacteria,2MQDM@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
k59_130150_1	1499967.BAYZ01000154_gene1502	2.29e-46	168.0	COG5421@1|root,COG5421@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_46684_1	1121403.AUCV01000015_gene4702	3.21e-51	174.0	COG2805@1|root,COG2805@2|Bacteria,1MU3J@1224|Proteobacteria,42M7F@68525|delta/epsilon subdivisions,2WJ4Z@28221|Deltaproteobacteria,2MHXJ@213118|Desulfobacterales	28221|Deltaproteobacteria	NU	PFAM type II secretion system protein E	pilT1	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
k59_84527_1	1035196.HMPREF9998_01359	3.17e-34	131.0	COG1319@1|root,COG1319@2|Bacteria,1TQA5@1239|Firmicutes,248WI@186801|Clostridia,25UH9@186804|Peptostreptococcaceae	186801|Clostridia	C	CO dehydrogenase flavoprotein C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	CO_deh_flav_C,FAD_binding_5
k59_39164_2	1045004.OKIT_0553	1.01e-36	129.0	2AK1X@1|root,31ARI@2|Bacteria,1V717@1239|Firmicutes,4HIQ9@91061|Bacilli,4AXZF@81850|Leuconostocaceae	91061|Bacilli	S	Pyrimidine dimer DNA glycosylase	yqeB	-	-	-	-	-	-	-	-	-	-	-	Pyr_excise
k59_167881_1	879212.DespoDRAFT_01398	4.65e-62	203.0	COG0304@1|root,COG0304@2|Bacteria,1MU1X@1224|Proteobacteria,42YVN@68525|delta/epsilon subdivisions,2WU2B@28221|Deltaproteobacteria,2MMVP@213118|Desulfobacterales	28221|Deltaproteobacteria	IQ	Beta-ketoacyl synthase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
k59_152980_1	258052.JNYV01000011_gene2816	2.42e-47	171.0	COG1021@1|root,COG1021@2|Bacteria,2I2IR@201174|Actinobacteria,2M42P@2063|Kitasatospora	201174|Actinobacteria	Q	AMP-binding enzyme C-terminal domain	entE	-	2.7.7.58,6.3.2.14	ko:K02363,ko:K12238	ko01053,ko01110,ko01130,map01053,map01110,map01130	-	R07644	RC00162,RC03046	ko00000,ko00001,ko01000,ko01008	-	-	-	AMP-binding,AMP-binding_C
k59_205982_1	1121405.dsmv_2856	1.99e-30	127.0	COG3039@1|root,COG3039@2|Bacteria,1PKUP@1224|Proteobacteria,43ECD@68525|delta/epsilon subdivisions,2X0BQ@28221|Deltaproteobacteria,2MP4F@213118|Desulfobacterales	28221|Deltaproteobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_23998_1	983545.Glaag_1305	1.64e-16	78.6	COG0835@1|root,COG0835@2|Bacteria,1RAH1@1224|Proteobacteria,1SYDF@1236|Gammaproteobacteria,466IY@72275|Alteromonadaceae	1236|Gammaproteobacteria	NT	COG0835 Chemotaxis signal transduction protein	cheW	-	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
k59_23998_2	763034.HMPREF9446_02018	3.97e-22	97.8	COG0745@1|root,COG2207@1|root,COG3292@1|root,COG5002@1|root,COG0745@2|Bacteria,COG2207@2|Bacteria,COG3292@2|Bacteria,COG5002@2|Bacteria,4P0IA@976|Bacteroidetes,2FWSR@200643|Bacteroidia,4ANR8@815|Bacteroidaceae	976|Bacteroidetes	T	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HTH_18,HisKA,Reg_prop,Response_reg,Y_Y_Y
k59_39168_1	530564.Psta_3595	1.98e-35	142.0	COG1716@1|root,COG2203@1|root,COG2204@1|root,COG1716@2|Bacteria,COG2203@2|Bacteria,COG2204@2|Bacteria,2IY6A@203682|Planctomycetes	203682|Planctomycetes	T	Ornithine decarboxylase inhibitor-putative sigma54 transciptional regulator	-	-	-	ko:K02584	ko02020,map02020	-	-	-	ko00000,ko00001,ko03000	-	-	-	FHA,GAF,GAF_2,HTH_8,Sigma54_activat
k59_77203_1	742735.HMPREF9467_02611	4.35e-46	166.0	COG0584@1|root,COG0584@2|Bacteria,1UGF1@1239|Firmicutes,25E4R@186801|Clostridia,21YGG@1506553|Lachnoclostridium	186801|Clostridia	C	glycerophosphoryl diester phosphodiesterase	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD,GPDPase_memb
k59_107334_1	1265505.ATUG01000002_gene2120	1.43e-100	316.0	COG3264@1|root,COG3264@2|Bacteria,1MWSA@1224|Proteobacteria,42N78@68525|delta/epsilon subdivisions,2WM0M@28221|Deltaproteobacteria,2MHVS@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Mechanosensitive ion channel	mscS-2	-	-	-	-	-	-	-	-	-	-	-	MS_channel
k59_122543_1	984262.SGRA_2225	1.45e-27	110.0	COG2339@1|root,COG2339@2|Bacteria,4NGUS@976|Bacteroidetes,1IXTR@117747|Sphingobacteriia	976|Bacteroidetes	S	Protease prsW family	-	-	-	-	-	-	-	-	-	-	-	-	PrsW-protease
k59_175618_1	1121405.dsmv_0049	5.75e-38	142.0	COG4191@1|root,COG4191@2|Bacteria,1MY12@1224|Proteobacteria,42PID@68525|delta/epsilon subdivisions,2WJVW@28221|Deltaproteobacteria,2MI1P@213118|Desulfobacterales	28221|Deltaproteobacteria	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_9
k59_39170_1	439235.Dalk_1184	3.29e-41	147.0	COG0758@1|root,COG1948@1|root,COG0758@2|Bacteria,COG1948@2|Bacteria,1MVF6@1224|Proteobacteria,42N10@68525|delta/epsilon subdivisions,2WJI9@28221|Deltaproteobacteria,2MHSD@213118|Desulfobacterales	28221|Deltaproteobacteria	LU	TIGRFAM DNA protecting protein DprA	dprA	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A
k59_107340_1	1121396.KB893035_gene3569	3.04e-64	221.0	COG0145@1|root,COG0146@1|root,COG0145@2|Bacteria,COG0146@2|Bacteria,1MU2Y@1224|Proteobacteria,42NFP@68525|delta/epsilon subdivisions,2X7WN@28221|Deltaproteobacteria,2MJWY@213118|Desulfobacterales	28221|Deltaproteobacteria	EQ	Hydantoinase oxoprolinase N-terminal region	-	-	3.5.2.9	ko:K01469	ko00480,map00480	-	R00251	RC00553	ko00000,ko00001,ko01000	-	-	-	Hydant_A_N,Hydantoinase_A,Hydantoinase_B
k59_1155_1	933262.AXAM01000016_gene191	9.44e-39	136.0	COG0670@1|root,COG0670@2|Bacteria,1MU69@1224|Proteobacteria,42MWD@68525|delta/epsilon subdivisions,2WMG9@28221|Deltaproteobacteria,2MJCA@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Belongs to the BI1 family	ybhL	-	-	ko:K06890,ko:K19416	-	M00742	-	-	ko00000,ko00002,ko02000	1.A.14.2.1	-	-	Bax1-I
k59_167892_1	439235.Dalk_4976	5.9e-97	293.0	COG1145@1|root,COG1145@2|Bacteria,1MW11@1224|Proteobacteria,42NUY@68525|delta/epsilon subdivisions,2WK01@28221|Deltaproteobacteria,2MMY1@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4
k59_205989_1	1232437.KL661961_gene3035	7.64e-207	585.0	COG0730@1|root,COG0730@2|Bacteria,1N1I6@1224|Proteobacteria,42N92@68525|delta/epsilon subdivisions,2WJT2@28221|Deltaproteobacteria,2MIX7@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Sulfite exporter TauE/SafE	-	-	-	-	-	-	-	-	-	-	-	-	TauE
k59_175624_1	583355.Caka_2137	2.38e-21	93.2	COG3735@1|root,COG3735@2|Bacteria,46VTS@74201|Verrucomicrobia	74201|Verrucomicrobia	S	TraB family	-	-	-	ko:K09973	-	-	-	-	ko00000	-	-	-	TraB
k59_39176_1	82654.Pse7367_1013	2.57e-118	367.0	COG0058@1|root,COG0058@2|Bacteria,1FZUX@1117|Cyanobacteria,1H71S@1150|Oscillatoriales	1117|Cyanobacteria	G	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties	-	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	Phosphorylase
k59_54288_1	56780.SYN_01459	4.05e-54	177.0	COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,42MV1@68525|delta/epsilon subdivisions,2WK9W@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	PFAM ABC transporter	-	-	-	ko:K01990,ko:K01992,ko:K09695	ko02010,map02010	M00252,M00254	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.102	-	-	ABC2_membrane_3,ABC_tran
k59_54288_2	56780.SYN_01460	4.28e-56	182.0	COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,42PIB@68525|delta/epsilon subdivisions,2WKFC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
k59_198293_1	456442.Mboo_1496	4.14e-24	102.0	COG3920@1|root,arCOG02330@1|root,arCOG02350@1|root,arCOG02330@2157|Archaea,arCOG02335@2157|Archaea,arCOG02350@2157|Archaea	2157|Archaea	T	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	-	-	-	ko:K02485	-	-	-	-	ko00000,ko02022	-	-	-	GAF,GAF_2,HATPase_c,HisKA,HisKA_2,PAS,PAS_3,PAS_4,PAS_9,Response_reg
k59_198293_2	1232437.KL662040_gene2136	2.5e-262	729.0	COG1032@1|root,COG1032@2|Bacteria,1MY2Y@1224|Proteobacteria,42NG3@68525|delta/epsilon subdivisions,2WJ95@28221|Deltaproteobacteria,2MJ57@213118|Desulfobacterales	28221|Deltaproteobacteria	C	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,DUF4070,Radical_SAM
k59_160580_1	880073.Calab_2683	6.35e-43	156.0	COG1007@1|root,COG1007@2|Bacteria,2NNMY@2323|unclassified Bacteria	2|Bacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN	GO:0003674,GO:0003824,GO:0003954,GO:0008137,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
k59_69460_1	933262.AXAM01000001_gene347	5.49e-54	184.0	COG1797@1|root,COG1797@2|Bacteria,1MV7Z@1224|Proteobacteria,42M8T@68525|delta/epsilon subdivisions,2WIXE@28221|Deltaproteobacteria,2MHZW@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source	cbiA	-	6.3.5.11,6.3.5.9	ko:K02224	ko00860,ko01100,ko01120,map00860,map01100,map01120	-	R05224,R05815	RC00010,RC01301	ko00000,ko00001,ko01000	-	-	-	AAA_26,CbiA,GATase_3
k59_160581_1	333138.LQ50_19480	2.4e-10	62.8	COG3090@1|root,COG3090@2|Bacteria,1V3PZ@1239|Firmicutes,4HI3P@91061|Bacilli,1ZFMD@1386|Bacillus	91061|Bacilli	G	Tripartite ATP-independent periplasmic transporters, DctQ component	-	-	-	-	-	-	-	-	-	-	-	-	DctQ
k59_137743_2	1033738.CAEP01000137_gene1483	1.54e-22	95.9	2C0BD@1|root,33ZWH@2|Bacteria,1VY4T@1239|Firmicutes,4HXM0@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_198299_1	96561.Dole_2846	4.32e-50	173.0	COG4591@1|root,COG4591@2|Bacteria,1MVV7@1224|Proteobacteria,42MV0@68525|delta/epsilon subdivisions,2WITK@28221|Deltaproteobacteria,2MHM1@213118|Desulfobacterales	28221|Deltaproteobacteria	M	TIGRFAM lipoprotein releasing system, transmembrane protein, LolC E family	lolC	-	-	ko:K09808	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125	-	-	FtsX,MacB_PCD
k59_221221_1	933262.AXAM01000005_gene2509	7.59e-69	229.0	COG1298@1|root,COG1298@2|Bacteria,1MUF3@1224|Proteobacteria,42NB2@68525|delta/epsilon subdivisions,2WIWG@28221|Deltaproteobacteria,2MI0U@213118|Desulfobacterales	28221|Deltaproteobacteria	N	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin	flhA	-	-	ko:K02400	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	FHIPEP
k59_39198_1	96561.Dole_1397	3.11e-86	263.0	COG0620@1|root,COG0620@2|Bacteria,1QB3M@1224|Proteobacteria,42NP4@68525|delta/epsilon subdivisions,2WK9Z@28221|Deltaproteobacteria,2MJ74@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1173_1	1121127.JAFA01000006_gene5633	3.21e-33	130.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,2VH80@28216|Betaproteobacteria,1K09P@119060|Burkholderiaceae	28216|Betaproteobacteria	IQ	amp-dependent synthetase and ligase	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
k59_183182_1	1121403.AUCV01000002_gene542	3.92e-20	85.5	COG0589@1|root,COG0589@2|Bacteria,1N5PT@1224|Proteobacteria,42UH3@68525|delta/epsilon subdivisions,2WR0A@28221|Deltaproteobacteria,2MKTU@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
k59_183182_2	768671.ThimaDRAFT_0156	1.4e-09	63.5	COG1262@1|root,COG1262@2|Bacteria,1R6GS@1224|Proteobacteria,1S5ET@1236|Gammaproteobacteria,1WYQP@135613|Chromatiales	135613|Chromatiales	S	Protein of unknown function (DUF1566)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1566
k59_130190_2	565034.BHWA1_01969	6.05e-24	108.0	COG1783@1|root,COG1783@2|Bacteria	2|Bacteria	S	DNA packaging	xtmB	-	-	ko:K06909	-	-	-	-	ko00000	-	-	-	Terminase_3,Terminase_3C
k59_221238_1	269797.Mbar_A1372	8.44e-25	99.4	COG1601@1|root,arCOG01640@2157|Archaea,2XTVZ@28890|Euryarchaeota,2N9JI@224756|Methanomicrobia	224756|Methanomicrobia	J	eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA	eif2b	-	-	ko:K03238	ko03013,map03013	-	-	-	ko00000,ko00001,ko01009,ko03012	-	-	-	TRAM,eIF-5_eIF-2B
k59_221238_2	694429.Pyrfu_1958	1.45e-19	83.6	COG2412@1|root,arCOG04051@2157|Archaea,2XR9B@28889|Crenarchaeota	28889|Crenarchaeota	S	Protein of unknown function (DUF424)	-	-	-	ko:K09148	-	-	-	-	ko00000	-	-	-	DUF424
k59_114892_1	179408.Osc7112_0619	1.27e-08	59.3	COG3179@1|root,COG3409@1|root,COG3770@1|root,COG3179@2|Bacteria,COG3409@2|Bacteria,COG3770@2|Bacteria,1G1SC@1117|Cyanobacteria,1H7Z0@1150|Oscillatoriales	1117|Cyanobacteria	M	Chitinase class I	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_19,PG_binding_1,Peptidase_M74,VanY
k59_54314_1	1122132.AQYH01000010_gene4196	0.000158	47.8	COG0330@1|root,COG0330@2|Bacteria,1MUM8@1224|Proteobacteria,2TRUY@28211|Alphaproteobacteria,4B7YY@82115|Rhizobiaceae	28211|Alphaproteobacteria	O	SPFH domain / Band 7 family	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
k59_46744_1	997353.HMPREF9144_0247	1.15e-09	63.9	COG1672@1|root,COG1672@2|Bacteria,4NGM3@976|Bacteroidetes,2FM92@200643|Bacteroidia	976|Bacteroidetes	S	ATPase (AAA superfamily)	-	-	-	ko:K06921	-	-	-	-	ko00000	-	-	-	ATPase_2
k59_122592_1	335543.Sfum_0457	1.87e-64	199.0	COG2185@1|root,COG2185@2|Bacteria,1RKGS@1224|Proteobacteria,42SKV@68525|delta/epsilon subdivisions,2WP2X@28221|Deltaproteobacteria,2MS30@213462|Syntrophobacterales	28221|Deltaproteobacteria	I	TIGRFAM methylmalonyl-CoA mutase C-terminal domain	-	-	5.4.99.2	ko:K01849	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding
k59_183651_1	1121405.dsmv_0608	1.8e-82	261.0	COG0773@1|root,COG0773@2|Bacteria,1MUC5@1224|Proteobacteria,42NMY@68525|delta/epsilon subdivisions,2WJ8S@28221|Deltaproteobacteria,2MHS5@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Belongs to the MurCDEF family	mpl	-	6.3.2.45	ko:K02558	-	-	-	-	ko00000,ko01000	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
k59_92722_1	335543.Sfum_1971	1.05e-26	108.0	COG1150@1|root,COG1150@2|Bacteria,1QWNB@1224|Proteobacteria,43BTA@68525|delta/epsilon subdivisions,2X741@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_22
k59_107916_1	1307759.JOMJ01000003_gene2075	1.28e-33	133.0	COG0574@1|root,COG3848@1|root,COG0574@2|Bacteria,COG3848@2|Bacteria,1MU0R@1224|Proteobacteria,42MW3@68525|delta/epsilon subdivisions,2WIXV@28221|Deltaproteobacteria,2M800@213115|Desulfovibrionales	28221|Deltaproteobacteria	G	PFAM Pyruvate phosphate dikinase, PEP	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PPDK_N
k59_54966_1	909663.KI867150_gene1265	4.71e-63	212.0	COG0465@1|root,COG0465@2|Bacteria,1MU6J@1224|Proteobacteria,42M4Z@68525|delta/epsilon subdivisions,2WJZ3@28221|Deltaproteobacteria,2MQ7P@213462|Syntrophobacterales	28221|Deltaproteobacteria	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
k59_191342_1	70601.3257229	2.87e-27	114.0	COG1032@1|root,arCOG01356@2157|Archaea,2XU04@28890|Euryarchaeota,243ZB@183968|Thermococci	183968|Thermococci	C	B12 binding domain	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
k59_229246_1	935840.JAEQ01000021_gene4390	8.7e-53	179.0	COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,2TQMJ@28211|Alphaproteobacteria,43GWP@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	E	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system	-	-	-	ko:K02052	ko02024,map02024	M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11	-	-	ABC_tran,TOBE_2
k59_32080_1	1267533.KB906734_gene4243	5.01e-51	176.0	COG1171@1|root,COG1171@2|Bacteria,3Y2RI@57723|Acidobacteria,2JHRQ@204432|Acidobacteriia	204432|Acidobacteriia	E	PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit	-	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
k59_1710_1	439235.Dalk_3793	1.55e-87	273.0	COG4799@1|root,COG4799@2|Bacteria,1MVAX@1224|Proteobacteria,42N6D@68525|delta/epsilon subdivisions,2X5IJ@28221|Deltaproteobacteria,2MI9M@213118|Desulfobacterales	28221|Deltaproteobacteria	I	Carboxyl transferase domain	mccB	-	6.4.1.4,6.4.1.5	ko:K01969,ko:K13778	ko00280,ko00281,ko01100,map00280,map00281,map01100	M00036	R03494,R04138	RC00367,RC00942	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_3290	Carboxyl_trans
k59_27984_1	316067.Geob_1313	1.26e-44	159.0	COG3359@1|root,COG3359@2|Bacteria,1R6A2@1224|Proteobacteria,42MVN@68525|delta/epsilon subdivisions,2WK0C@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	RNase_H superfamily	-	-	-	ko:K07502	-	-	-	-	ko00000	-	-	-	RNase_H_2
k59_135034_1	944481.JAFP01000001_gene617	7.35e-80	253.0	COG0146@1|root,COG0146@2|Bacteria,1QU46@1224|Proteobacteria,43CGH@68525|delta/epsilon subdivisions,2WJ3J@28221|Deltaproteobacteria,2M6HY@213113|Desulfurellales	28221|Deltaproteobacteria	EQ	Hydantoinase B/oxoprolinase	hyuB	-	3.5.2.14	ko:K01474	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydantoinase_B
k59_233756_1	96561.Dole_2104	1.41e-61	197.0	COG1145@1|root,COG1145@2|Bacteria,1PW12@1224|Proteobacteria,42MZ9@68525|delta/epsilon subdivisions,2WN0W@28221|Deltaproteobacteria,2MHYH@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_6
k59_210834_1	1278073.MYSTI_00461	1.07e-11	71.2	COG4258@1|root,COG4258@2|Bacteria,1QX46@1224|Proteobacteria,42QK9@68525|delta/epsilon subdivisions,2WKGH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	MMPL family	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
k59_194801_1	1385513.N780_12765	1.83e-25	111.0	COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,4HBZ0@91061|Bacilli,2YA4X@289201|Pontibacillus	91061|Bacilli	T	Histidine kinase	resE	-	2.7.13.3	ko:K07651	ko02020,map02020	M00458	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4
k59_194801_2	1125863.JAFN01000001_gene17	1.29e-15	77.0	COG4566@1|root,COG4566@2|Bacteria,1PHNS@1224|Proteobacteria,431JN@68525|delta/epsilon subdivisions,2WWNY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
k59_157498_1	589865.DaAHT2_0339	1.47e-73	239.0	COG2262@1|root,COG2262@2|Bacteria,1MUA0@1224|Proteobacteria,42NA6@68525|delta/epsilon subdivisions,2WIMU@28221|Deltaproteobacteria,2MJ6H@213118|Desulfobacterales	28221|Deltaproteobacteria	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
k59_81806_1	398512.JQKC01000111_gene2504	1.09e-26	105.0	COG4467@1|root,COG4467@2|Bacteria	2|Bacteria	L	Involved in initiation control of chromosome replication	-	-	-	ko:K07484	-	-	-	-	ko00000	-	-	-	DDE_Tnp_IS66,zf-IS66
k59_142614_1	1121405.dsmv_0006	2.53e-87	265.0	COG2043@1|root,COG2043@2|Bacteria,1NR18@1224|Proteobacteria,42TWC@68525|delta/epsilon subdivisions,2WQ80@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM Uncharacterised ArCR, COG2043	-	-	-	-	-	-	-	-	-	-	-	-	DUF169
k59_135037_1	765913.ThidrDRAFT_0358	4.28e-18	82.0	COG0189@1|root,COG0189@2|Bacteria,1MX62@1224|Proteobacteria,1RM8B@1236|Gammaproteobacteria,1WX7Z@135613|Chromatiales	135613|Chromatiales	HJ	Belongs to the RimK family	rimK	-	-	ko:K05844	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	RimK
k59_135037_2	1265505.ATUG01000002_gene2121	1.16e-49	162.0	COG4067@1|root,COG4067@2|Bacteria,1RGX8@1224|Proteobacteria,43B1T@68525|delta/epsilon subdivisions	1224|Proteobacteria	O	Putative ATP-dependant zinc protease	-	-	-	-	-	-	-	-	-	-	-	-	Zn_protease
k59_89190_1	1121405.dsmv_0475	2.08e-85	263.0	COG0772@1|root,COG0772@2|Bacteria,1MUK3@1224|Proteobacteria,42MQT@68525|delta/epsilon subdivisions,2WIP1@28221|Deltaproteobacteria,2MJ4R@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Peptidoglycan polymerase that is essential for cell wall elongation	mrdB	-	-	ko:K05837	-	-	-	-	ko00000,ko03036	-	-	-	FTSW_RODA_SPOVE
k59_179715_1	305700.B447_07137	2.14e-161	471.0	COG2211@1|root,COG2211@2|Bacteria,1MWSH@1224|Proteobacteria,2VJEQ@28216|Betaproteobacteria,2KUQ3@206389|Rhodocyclales	206389|Rhodocyclales	G	BT1 family	-	-	-	-	-	-	-	-	-	-	-	-	BT1
k59_66135_1	1121405.dsmv_1014	5.14e-79	249.0	COG1925@1|root,COG1925@2|Bacteria,1PW7I@1224|Proteobacteria,42N77@68525|delta/epsilon subdivisions,2WKSU@28221|Deltaproteobacteria,2MI26@213118|Desulfobacterales	28221|Deltaproteobacteria	G	phosphoenolpyruvate-dependent sugar phosphotransferase system	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_20627_1	204773.HEAR2872	5.49e-15	77.4	COG0627@1|root,COG0627@2|Bacteria,1MY73@1224|Proteobacteria,2VS12@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Serine hydrolase involved in the detoxification of formaldehyde	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
k59_66137_1	644968.DFW101_0374	5.36e-39	145.0	COG2204@1|root,COG4191@1|root,COG2204@2|Bacteria,COG4191@2|Bacteria,1QZPK@1224|Proteobacteria,42NQE@68525|delta/epsilon subdivisions,2WJPH@28221|Deltaproteobacteria,2M8MZ@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,PAS_4,PAS_9,Response_reg
k59_66137_2	1121438.JNJA01000007_gene1659	2.07e-11	60.8	COG2204@1|root,COG2204@2|Bacteria,1RHQV@1224|Proteobacteria,42T2A@68525|delta/epsilon subdivisions,2WPA0@28221|Deltaproteobacteria,2MBWC@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
k59_66138_1	1123279.ATUS01000002_gene245	2.7e-07	57.8	COG0457@1|root,COG0457@2|Bacteria,1MYB8@1224|Proteobacteria,1RQIX@1236|Gammaproteobacteria,1J5FN@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	O	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_14,TPR_16,TPR_19,TPR_2,TPR_6,TPR_8
k59_74075_1	933262.AXAM01000040_gene1215	4.03e-63	199.0	COG0241@1|root,COG0241@2|Bacteria,1RDGR@1224|Proteobacteria,42SCB@68525|delta/epsilon subdivisions,2WPEA@28221|Deltaproteobacteria,2MJSF@213118|Desulfobacterales	28221|Deltaproteobacteria	E	D,D-heptose 1,7-bisphosphate phosphatase	-	-	3.1.3.82,3.1.3.83	ko:K03273	ko00540,ko01100,map00540,map01100	M00064	R05647,R09771	RC00017	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hydrolase_like
k59_96832_1	760568.Desku_2752	1.2e-146	436.0	COG0243@1|root,COG0243@2|Bacteria,1TPZG@1239|Firmicutes,247JV@186801|Clostridia,2605J@186807|Peptococcaceae	186801|Clostridia	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	1.8.5.5,1.8.5.6	ko:K08352,ko:K21307	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R10149,R11487	RC00168,RC02823	ko00000,ko00001,ko01000,ko02000	5.A.3.5	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding,TAT_signal
k59_217958_1	1307759.JOMJ01000003_gene2349	4.12e-30	123.0	COG5002@1|root,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,42NK9@68525|delta/epsilon subdivisions,2WMCQ@28221|Deltaproteobacteria,2MH9G@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS_4,Response_reg
k59_135056_1	1211115.ALIQ01000108_gene1209	8.72e-24	105.0	COG0784@1|root,COG4191@1|root,COG0784@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2TR8X@28211|Alphaproteobacteria,3NAFU@45404|Beijerinckiaceae	28211|Alphaproteobacteria	T	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_4,Response_reg
k59_59282_2	722417.D5GV46_9CAUD	1.52e-40	152.0	4QEIG@10239|Viruses,4R0E7@35237|dsDNA viruses  no RNA stage,4QTGA@28883|Caudovirales,4QJNG@10662|Myoviridae	10662|Myoviridae	S	regulation of transcription, DNA-dependent	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_127330_1	335543.Sfum_1829	5.36e-43	160.0	COG1924@1|root,COG3580@1|root,COG1924@2|Bacteria,COG3580@2|Bacteria,1PKG6@1224|Proteobacteria,42MY4@68525|delta/epsilon subdivisions,2WJFI@28221|Deltaproteobacteria,2MQ8R@213462|Syntrophobacterales	28221|Deltaproteobacteria	I	BadF BadG BcrA BcrD	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG,DUF2229
k59_119130_1	525897.Dbac_2289	1.31e-22	98.6	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42PZ5@68525|delta/epsilon subdivisions,2WM1A@28221|Deltaproteobacteria,2MAT9@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	SMART ATP-binding region ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Response_reg,SBP_bac_3
k59_119130_2	525897.Dbac_2288	1.69e-51	178.0	COG2204@1|root,COG2204@2|Bacteria,1PAPS@1224|Proteobacteria,42NMK@68525|delta/epsilon subdivisions,2WK6K@28221|Deltaproteobacteria,2M8IR@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	two component, sigma54 specific, transcriptional regulator, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
k59_135066_1	96561.Dole_1338	5.9e-83	261.0	COG1055@1|root,COG1055@2|Bacteria,1MUX4@1224|Proteobacteria,42MHN@68525|delta/epsilon subdivisions,2WJU0@28221|Deltaproteobacteria,2MMHX@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Arsenical pump membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS
k59_13892_1	1408423.JHYA01000004_gene2248	1.41e-35	134.0	COG1284@1|root,COG1284@2|Bacteria,1TQTP@1239|Firmicutes,4H3DB@909932|Negativicutes	909932|Negativicutes	S	Psort location CytoplasmicMembrane, score 10.00	-	-	-	-	-	-	-	-	-	-	-	-	DUF2179,YitT_membrane
k59_66152_2	868131.MSWAN_1185	1e-28	106.0	COG0640@1|root,arCOG00731@2157|Archaea,2XYSK@28890|Euryarchaeota	28890|Euryarchaeota	K	transcriptional	-	-	-	-	-	-	-	-	-	-	-	-	HTH_5
k59_96848_1	1123248.KB893351_gene1791	5.36e-64	214.0	COG3039@1|root,COG3039@2|Bacteria,4PKH0@976|Bacteroidetes,1J0XZ@117747|Sphingobacteriia	976|Bacteroidetes	L	Transposase domain (DUF772)	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_6,DUF772
k59_28008_1	1121405.dsmv_3041	3.28e-90	283.0	COG0441@1|root,COG0441@2|Bacteria,1MUP2@1224|Proteobacteria,42M20@68525|delta/epsilon subdivisions,2WJ2N@28221|Deltaproteobacteria,2MI0Z@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD
k59_188271_1	1304885.AUEY01000001_gene3192	9.74e-60	186.0	COG0607@1|root,COG0607@2|Bacteria,1RE94@1224|Proteobacteria,42RGF@68525|delta/epsilon subdivisions,2WNWK@28221|Deltaproteobacteria,2MK0V@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
k59_89864_1	177437.HRM2_28820	1.82e-128	373.0	COG0123@1|root,COG0123@2|Bacteria,1MU7P@1224|Proteobacteria,42NQP@68525|delta/epsilon subdivisions,2WIQD@28221|Deltaproteobacteria,2MJIG@213118|Desulfobacterales	28221|Deltaproteobacteria	BQ	PFAM Histone deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Hist_deacetyl
k59_36975_1	96561.Dole_1162	1.41e-66	213.0	COG0204@1|root,COG0204@2|Bacteria,1MVWG@1224|Proteobacteria,42PBW@68525|delta/epsilon subdivisions,2WJV5@28221|Deltaproteobacteria,2MIXQ@213118|Desulfobacterales	28221|Deltaproteobacteria	I	PFAM phospholipid glycerol acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
k59_158181_1	1217652.F954_01946	9.97e-27	113.0	COG0188@1|root,COG0188@2|Bacteria,1MURI@1224|Proteobacteria,1RMTC@1236|Gammaproteobacteria,3NIU5@468|Moraxellaceae	1236|Gammaproteobacteria	L	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule	parC	GO:0000819,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006265,GO:0006276,GO:0006725,GO:0006807,GO:0006996,GO:0007049,GO:0007059,GO:0007062,GO:0008150,GO:0008152,GO:0009330,GO:0009987,GO:0016020,GO:0016043,GO:0019897,GO:0019898,GO:0022402,GO:0030541,GO:0032991,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0098813,GO:1901360,GO:1901363	-	ko:K02621	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
k59_59841_1	526222.Desal_1353	2.23e-70	233.0	COG1657@1|root,COG1657@2|Bacteria,1MUIP@1224|Proteobacteria,42Q4W@68525|delta/epsilon subdivisions,2WJ9H@28221|Deltaproteobacteria,2MASC@213115|Desulfovibrionales	28221|Deltaproteobacteria	I	Squalene-hopene cyclase C-terminal domain	shc-2	-	4.2.1.129,5.4.99.17,5.4.99.7	ko:K01852,ko:K06045	ko00100,ko00909,ko01100,ko01110,ko01130,map00100,map00909,map01100,map01110,map01130	M00101	R03199,R07322,R07323	RC00874,RC01850,RC01851	ko00000,ko00001,ko00002,ko01000	-	-	-	SQHop_cyclase_C,SQHop_cyclase_N
k59_59846_1	224719.Abm4_1186	1.91e-28	120.0	COG1042@1|root,arCOG01340@2157|Archaea,2XT9G@28890|Euryarchaeota,23NP5@183925|Methanobacteria	183925|Methanobacteria	C	CoA binding domain	acs	-	6.2.1.13	ko:K01905,ko:K22224	ko00010,ko00620,ko00640,ko01100,ko01120,map00010,map00620,map00640,map01100,map01120	-	R00229,R00920	RC00004,RC00012,RC00014	ko00000,ko00001,ko01000,ko01004	-	-	-	ATP-grasp_5,CoA_binding_2,Succ_CoA_lig
k59_158182_2	760192.Halhy_2757	8.59e-24	101.0	COG2133@1|root,COG2133@2|Bacteria,4NDV1@976|Bacteroidetes,1ISZC@117747|Sphingobacteriia	976|Bacteroidetes	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
k59_149891_1	469381.Dpep_1176	3.68e-67	215.0	COG0618@1|root,COG0618@2|Bacteria,3TBXW@508458|Synergistetes	508458|Synergistetes	S	3'(2'),5'-bisphosphate nucleotidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_188891_1	335543.Sfum_1561	2.82e-101	298.0	COG0092@1|root,COG0092@2|Bacteria,1MUAI@1224|Proteobacteria,42N5W@68525|delta/epsilon subdivisions,2WIU3@28221|Deltaproteobacteria,2MQ8I@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation	rpsC	GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02982	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KH_2,Ribosomal_S3_C
k59_14542_1	525897.Dbac_2078	2.15e-68	225.0	COG0272@1|root,COG0272@2|Bacteria,1MV3R@1224|Proteobacteria,42MC5@68525|delta/epsilon subdivisions,2WIT5@28221|Deltaproteobacteria,2M8QF@213115|Desulfovibrionales	28221|Deltaproteobacteria	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	-	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
k59_158186_1	933262.AXAM01000073_gene3359	4.15e-47	158.0	COG0047@1|root,COG0047@2|Bacteria,1MU4Y@1224|Proteobacteria,42MNY@68525|delta/epsilon subdivisions,2WJ6C@28221|Deltaproteobacteria,2MI5J@213118|Desulfobacterales	28221|Deltaproteobacteria	F	CobB/CobQ-like glutamine amidotransferase domain	purQ	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase_5
k59_158186_2	1265505.ATUG01000001_gene3368	4.06e-30	121.0	COG0046@1|root,COG1828@1|root,COG0046@2|Bacteria,COG1828@2|Bacteria,1MYN4@1224|Proteobacteria,42M08@68525|delta/epsilon subdivisions,2WITS@28221|Deltaproteobacteria,2MIFX@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C,PurS
k59_97381_2	439235.Dalk_4322	3.09e-26	108.0	COG3290@1|root,COG4191@1|root,COG3290@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42PZ5@68525|delta/epsilon subdivisions,2WM5Q@28221|Deltaproteobacteria,2MJDG@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
k59_149897_1	1121447.JONL01000010_gene2381	1.12e-06	54.7	COG1262@1|root,COG1262@2|Bacteria,1R6GS@1224|Proteobacteria,42R3Z@68525|delta/epsilon subdivisions,2WN4D@28221|Deltaproteobacteria,2MGMW@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF1566)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1566
k59_158187_1	1121405.dsmv_1454	4.06e-106	331.0	COG2937@1|root,COG2937@2|Bacteria,1MWZ6@1224|Proteobacteria,42MN4@68525|delta/epsilon subdivisions,2WJJ5@28221|Deltaproteobacteria,2MHRG@213118|Desulfobacterales	28221|Deltaproteobacteria	I	Belongs to the GPAT DAPAT family	plsB	-	2.3.1.15	ko:K00631	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
k59_203697_2	335543.Sfum_3450	3.23e-92	284.0	COG2270@1|root,COG2270@2|Bacteria,1MWXB@1224|Proteobacteria,42N2B@68525|delta/epsilon subdivisions,2WJS9@28221|Deltaproteobacteria,2MQ4E@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Vacuole effluxer Atg22 like	-	-	-	ko:K06902	ko04138,map04138	-	-	-	ko00000,ko00001,ko02000,ko04131	2.A.1.24,9.A.15.1	-	-	ATG22
k59_218521_1	1232437.KL662047_gene5166	3.49e-22	92.0	COG1472@1|root,COG1472@2|Bacteria,1MVAJ@1224|Proteobacteria,42N8K@68525|delta/epsilon subdivisions,2WN0Z@28221|Deltaproteobacteria,2MHV6@213118|Desulfobacterales	28221|Deltaproteobacteria	G	PFAM glycoside hydrolase family 3 domain protein	-	-	3.2.1.52	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	M00628	R00022,R05963,R07809,R07810,R10831	RC00049	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyco_hydro_3,Glyco_hydro_3_C
k59_218521_2	864051.BurJ1DRAFT_3618	1.07e-26	110.0	COG0533@1|root,COG0533@2|Bacteria,1MU6S@1224|Proteobacteria,2VHDR@28216|Betaproteobacteria,1KK5I@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	-	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
k59_188907_1	1121405.dsmv_3527	1.13e-93	283.0	COG0765@1|root,COG0765@2|Bacteria,1MV3I@1224|Proteobacteria,42PDT@68525|delta/epsilon subdivisions,2WKER@28221|Deltaproteobacteria,2MIIP@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K09971	ko02010,map02010	M00232	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3.18,3.A.1.3.7,3.A.1.3.8	-	-	BPD_transp_1
k59_149911_1	1125863.JAFN01000001_gene2501	8.12e-19	82.4	COG1314@1|root,COG1314@2|Bacteria,1NJ1D@1224|Proteobacteria,42TKW@68525|delta/epsilon subdivisions,2WRA3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	U	PFAM Preprotein translocase SecG subunit	secG	-	-	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecG
k59_149911_2	1469607.KK073768_gene3498	5.21e-14	70.1	COG0149@1|root,COG0149@2|Bacteria,1FZYM@1117|Cyanobacteria,1HJDN@1161|Nostocales	1117|Cyanobacteria	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
k59_28629_1	335543.Sfum_1977	1.86e-90	293.0	COG1148@1|root,COG1148@2|Bacteria,1QUM4@1224|Proteobacteria,42MPP@68525|delta/epsilon subdivisions,2WJ3U@28221|Deltaproteobacteria,2MQTI@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_4,Fer4_7,Pyr_redox_2
k59_43863_1	335543.Sfum_0821	3.08e-66	226.0	COG1148@1|root,COG2204@1|root,COG1148@2|Bacteria,COG2204@2|Bacteria,1QUM4@1224|Proteobacteria,42MPP@68525|delta/epsilon subdivisions,2WJ3U@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	4Fe-4S ferredoxin iron-sulfur binding domain protein	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,FAD_oxidored,Fer4,Fer4_7,NAD_binding_8,Pyr_redox_2,Response_reg
k59_43863_2	335543.Sfum_0820	1.02e-45	153.0	COG1150@1|root,COG1150@2|Bacteria,1RHH3@1224|Proteobacteria,42SBS@68525|delta/epsilon subdivisions,2WPKY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	4Fe-4S dicluster domain	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03390,ko:K16887	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4_17,Fer4_9
k59_135826_1	1437448.AZRT01000188_gene4158	7.79e-41	145.0	COG4664@1|root,COG4664@2|Bacteria,1R4MZ@1224|Proteobacteria,2TQNR@28211|Alphaproteobacteria,1J3SH@118882|Brucellaceae	28211|Alphaproteobacteria	Q	Tripartite ATP-independent periplasmic transporter, DctM component	dctM1	-	-	-	-	-	-	-	-	-	-	-	DctM
k59_135826_2	867845.KI911784_gene246	2.84e-20	88.6	COG0589@1|root,COG0589@2|Bacteria	2|Bacteria	T	AMP binding	-	-	-	-	-	-	-	-	-	-	-	-	CBS,Usp
k59_14557_1	880072.Desac_1620	4.24e-64	211.0	COG1797@1|root,COG1797@2|Bacteria,1MV7Z@1224|Proteobacteria,42M8T@68525|delta/epsilon subdivisions,2WIXE@28221|Deltaproteobacteria,2MQYU@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source	cbiA	-	6.3.5.11,6.3.5.9	ko:K02224	ko00860,ko01100,ko01120,map00860,map01100,map01120	-	R05224,R05815	RC00010,RC01301	ko00000,ko00001,ko01000	-	-	-	AAA_26,CbiA,GATase_3
k59_112769_1	335543.Sfum_1546	8.33e-119	345.0	COG0081@1|root,COG0081@2|Bacteria,1MUE6@1224|Proteobacteria,42MZP@68525|delta/epsilon subdivisions,2WJ1Z@28221|Deltaproteobacteria,2MQWW@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release	rplA	GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02863	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L1
k59_234387_1	1121405.dsmv_3151	5.18e-65	219.0	COG0699@1|root,COG0699@2|Bacteria,1R3WJ@1224|Proteobacteria,42N0G@68525|delta/epsilon subdivisions,2WKFJ@28221|Deltaproteobacteria,2MJ5I@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Dynamin family	-	-	-	-	-	-	-	-	-	-	-	-	Dynamin_N
k59_89890_1	933262.AXAM01000017_gene3144	1.8e-19	79.3	COG1908@1|root,COG1908@2|Bacteria,1RCZY@1224|Proteobacteria,42T3M@68525|delta/epsilon subdivisions,2WPVI@28221|Deltaproteobacteria,2MKVM@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Methyl-viologen-reducing hydrogenase, delta subunit	-	-	-	-	-	-	-	-	-	-	-	-	FlpD
k59_89890_2	1957.JODX01000014_gene1091	2.61e-45	154.0	COG0663@1|root,COG0663@2|Bacteria,2GP22@201174|Actinobacteria	201174|Actinobacteria	K	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep,Hexapep_2
k59_43868_1	880072.Desac_0553	1.29e-96	294.0	COG0304@1|root,COG0304@2|Bacteria,1MU1X@1224|Proteobacteria,42MUZ@68525|delta/epsilon subdivisions,2WJT6@28221|Deltaproteobacteria,2MQ97@213462|Syntrophobacterales	28221|Deltaproteobacteria	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabF	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
k59_180429_1	555079.Toce_1916	3.22e-49	174.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,1TNZE@1239|Firmicutes,2480H@186801|Clostridia,42EWB@68295|Thermoanaerobacterales	186801|Clostridia	H	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	ACPS,Carb_kinase,YjeF_N
k59_211535_1	443144.GM21_0323	1.9e-44	163.0	COG0507@1|root,COG0507@2|Bacteria,1MW43@1224|Proteobacteria,42NRK@68525|delta/epsilon subdivisions,2WIM6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD	recD	-	3.1.11.5	ko:K03581	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AAA_30,UvrD_C_2
k59_234389_1	1282362.AEAC466_07860	2.09e-16	84.7	COG0470@1|root,COG0470@2|Bacteria,1MY1W@1224|Proteobacteria,2TV3E@28211|Alphaproteobacteria,2KF0N@204458|Caulobacterales	204458|Caulobacterales	L	DNA polymerase III	-	-	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2
k59_66729_1	1121405.dsmv_1714	6.17e-107	313.0	COG0356@1|root,COG0356@2|Bacteria,1MV87@1224|Proteobacteria,42NZS@68525|delta/epsilon subdivisions,2WINI@28221|Deltaproteobacteria,2MI5U@213118|Desulfobacterales	28221|Deltaproteobacteria	C	it plays a direct role in the translocation of protons across the membrane	-	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
k59_149929_1	525146.Ddes_1274	2.48e-28	111.0	COG1259@1|root,COG1259@2|Bacteria,1RFFV@1224|Proteobacteria,42SCI@68525|delta/epsilon subdivisions,2WPWT@28221|Deltaproteobacteria,2M8KC@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Bifunctional nuclease	-	-	-	ko:K08999	-	-	-	-	ko00000	-	-	-	DNase-RNase
k59_14564_1	1265505.ATUG01000002_gene2671	3.15e-63	214.0	COG0370@1|root,COG0370@2|Bacteria,1MUZC@1224|Proteobacteria,42MCY@68525|delta/epsilon subdivisions,2WIWJ@28221|Deltaproteobacteria,2MIW3@213118|Desulfobacterales	28221|Deltaproteobacteria	P	transporter of a GTP-driven Fe(2 ) uptake system	feoB	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoB_C,FeoB_N,Gate
k59_218533_1	56780.SYN_02536	4.05e-107	328.0	COG0119@1|root,COG0119@2|Bacteria,1R8DM@1224|Proteobacteria,42PDN@68525|delta/epsilon subdivisions,2WKIJ@28221|Deltaproteobacteria,2MQ4N@213462|Syntrophobacterales	28221|Deltaproteobacteria	E	PFAM Pyruvate carboxyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	HMGL-like,dCache_1
k59_222004_1	1265505.ATUG01000001_gene4016	1.73e-182	513.0	COG0667@1|root,COG0667@2|Bacteria,1MVEH@1224|Proteobacteria,42MDR@68525|delta/epsilon subdivisions,2WKUR@28221|Deltaproteobacteria,2MI64@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
k59_9688_1	304371.MCP_2481	7.09e-102	305.0	COG1759@1|root,arCOG04346@2157|Archaea,2XUFR@28890|Euryarchaeota,2N9HE@224756|Methanomicrobia	224756|Methanomicrobia	F	Protein of unknown function (DUF1246)	-	-	6.3.4.23	ko:K06863	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R06975	RC00263,RC00323	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF1246,DUF1297
k59_17079_2	439235.Dalk_2741	4.36e-22	96.3	COG1943@1|root,COG1943@2|Bacteria,1MX0E@1224|Proteobacteria,42NN0@68525|delta/epsilon subdivisions,2WM14@28221|Deltaproteobacteria,2MIW7@213118|Desulfobacterales	28221|Deltaproteobacteria	L	SMART Chromosomal replication initiator DnaA domain	-	-	-	-	-	-	-	-	-	-	-	-	Bac_DnaA_C,Y1_Tnp
k59_168687_1	933262.AXAM01000046_gene145	6.05e-104	316.0	COG0260@1|root,COG0260@2|Bacteria,1MUF9@1224|Proteobacteria,42M2G@68525|delta/epsilon subdivisions,2WJ80@28221|Deltaproteobacteria,2MIFW@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides	pepA	-	3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17,Peptidase_M17_N
k59_55274_1	555779.Dthio_PD0193	3.78e-26	111.0	COG0507@1|root,COG0507@2|Bacteria,1QCFP@1224|Proteobacteria,42NH5@68525|delta/epsilon subdivisions,2WKAR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	PIF1-like helicase	-	-	3.6.4.12	ko:K15255	-	-	-	-	ko00000,ko01000,ko03029,ko03032	-	-	-	HRDC,HTH_40,Herpes_Helicase,PIF1
k59_9695_1	1121405.dsmv_3781	1.17e-100	302.0	COG5421@1|root,COG5421@2|Bacteria,1R3NX@1224|Proteobacteria,42QDV@68525|delta/epsilon subdivisions,2WIRQ@28221|Deltaproteobacteria,2MN1S@213118|Desulfobacterales	68525|delta/epsilon subdivisions	L	PFAM transposase IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
k59_47608_2	1499967.BAYZ01000065_gene6086	7.71e-22	93.2	COG3938@1|root,COG3938@2|Bacteria,2NQES@2323|unclassified Bacteria	2|Bacteria	E	Proline racemase	-	GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016854,GO:0016855,GO:0018112,GO:0019752,GO:0036361,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0047661,GO:0050346,GO:0071704,GO:1901564	5.1.1.4	ko:K01777	ko00330,ko01100,map00330,map01100	-	R01255	RC00479	ko00000,ko00001,ko01000	-	-	-	Pro_racemase
k59_32314_1	742767.HMPREF9456_01407	5.69e-25	99.4	COG0177@1|root,COG0177@2|Bacteria,4NFF3@976|Bacteroidetes,2FM8U@200643|Bacteroidia,22WI0@171551|Porphyromonadaceae	976|Bacteroidetes	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD
k59_32314_2	1185653.A1A1_06537	6.54e-11	63.5	COG0488@1|root,COG0488@2|Bacteria,1TPAX@1239|Firmicutes,4H9ZK@91061|Bacilli,26DMH@186818|Planococcaceae	91061|Bacilli	S	ATPase components of ABC transporters with duplicated ATPase domains	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
k59_9697_1	933262.AXAM01000004_gene2404	5.74e-63	202.0	COG1189@1|root,COG1189@2|Bacteria,1MWP5@1224|Proteobacteria,42R2J@68525|delta/epsilon subdivisions,2WIJ6@28221|Deltaproteobacteria,2MIMF@213118|Desulfobacterales	28221|Deltaproteobacteria	J	PFAM ribosomal RNA methyltransferase RrmJ FtsJ	tlyA	-	2.1.1.226,2.1.1.227	ko:K06442	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ,S4
k59_138672_1	316067.Geob_0392	5.48e-98	310.0	COG0060@1|root,COG0060@2|Bacteria,1MVBQ@1224|Proteobacteria,42MKB@68525|delta/epsilon subdivisions,2WJ4W@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1,zf-FPG_IleRS
k59_85355_1	589865.DaAHT2_2316	2.15e-68	221.0	COG0044@1|root,COG0044@2|Bacteria,1MVXY@1224|Proteobacteria,42MJ9@68525|delta/epsilon subdivisions,2WJH8@28221|Deltaproteobacteria,2MI0K@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily	pyrC	GO:0003674,GO:0003824,GO:0004038,GO:0004151,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046390,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
k59_85358_1	933262.AXAM01000010_gene1349	2.74e-09	57.0	COG1196@1|root,COG1196@2|Bacteria,1MUAQ@1224|Proteobacteria,42MN9@68525|delta/epsilon subdivisions,2WJZF@28221|Deltaproteobacteria,2MHU0@213118|Desulfobacterales	28221|Deltaproteobacteria	D	Required for chromosome condensation and partitioning	smc	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
k59_229486_1	880072.Desac_0816	1.26e-72	230.0	COG0247@1|root,COG0247@2|Bacteria,1N5Q2@1224|Proteobacteria,42P5D@68525|delta/epsilon subdivisions,2WJ9I@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM Cysteine-rich	-	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_17
k59_92952_1	880071.Fleli_1823	2.27e-29	115.0	COG1423@1|root,COG1423@2|Bacteria	2|Bacteria	L	RNA ligase	-	-	-	-	-	-	-	-	-	-	-	-	RNA_ligase
k59_206878_2	525897.Dbac_0447	1.8e-13	68.2	COG0822@1|root,COG0822@2|Bacteria,1MZ7I@1224|Proteobacteria,42TH3@68525|delta/epsilon subdivisions,2WQ08@28221|Deltaproteobacteria,2MBFR@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	Nitrogen-fixing NifU domain protein	-	-	-	ko:K04488	-	-	-	-	ko00000	-	-	-	NifU_N
k59_1982_1	706587.Desti_2842	1.86e-21	86.7	2EUYT@1|root,33NE0@2|Bacteria,1P79U@1224|Proteobacteria,432X2@68525|delta/epsilon subdivisions,2WXB8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1982_2	933262.AXAM01000008_gene1980	8.28e-15	73.9	COG0760@1|root,COG0760@2|Bacteria,1MWV0@1224|Proteobacteria,42MPK@68525|delta/epsilon subdivisions,2WJM1@28221|Deltaproteobacteria,2MHM6@213118|Desulfobacterales	28221|Deltaproteobacteria	O	PFAM PpiC-type peptidyl-prolyl cis-trans isomerase	nifM	-	5.2.1.8	ko:K03770	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N_3
k59_100721_1	156889.Mmc1_1519	8.68e-90	291.0	COG1033@1|root,COG1033@2|Bacteria,1MUE1@1224|Proteobacteria,2TRI9@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	exporters of the RND superfamily	MA20_16090	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
k59_108602_1	439235.Dalk_0585	1.44e-48	177.0	COG0577@1|root,COG1340@1|root,COG2234@1|root,COG0577@2|Bacteria,COG1340@2|Bacteria,COG2234@2|Bacteria,1MVYE@1224|Proteobacteria,42PKN@68525|delta/epsilon subdivisions,2WIWP@28221|Deltaproteobacteria,2MIQI@213118|Desulfobacterales	28221|Deltaproteobacteria	V	FtsX-like permease family	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,PA,Peptidase_M28
k59_10294_1	335543.Sfum_2413	4.48e-75	256.0	COG3523@1|root,COG3523@2|Bacteria,1NRHK@1224|Proteobacteria,42Z87@68525|delta/epsilon subdivisions,2WTYM@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_184689_1	1232410.KI421422_gene1990	1.66e-26	109.0	COG1454@1|root,COG1454@2|Bacteria,1NTAV@1224|Proteobacteria,42Y7V@68525|delta/epsilon subdivisions,2WTJT@28221|Deltaproteobacteria,43TFK@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Iron-containing alcohol dehydrogenase	-	-	1.1.99.37,1.2.98.1	ko:K17067	ko00625,ko00680,ko01120,ko01200,map00625,map00680,map01120,map01200	-	R00614	RC00034,RC00188	ko00000,ko00001,ko01000	-	-	-	Fe-ADH
k59_101273_1	910964.GEAM_3025	1.16e-09	63.5	COG0524@1|root,COG0524@2|Bacteria,1R52G@1224|Proteobacteria,1RN4W@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway	rbsK	-	-	-	-	-	-	-	-	-	-	-	HTH_DeoR,PfkB
k59_101273_2	439481.Aboo_0801	3.94e-08	52.0	arCOG05330@1|root,arCOG05330@2157|Archaea,2Y24Y@28890|Euryarchaeota,3F3GX@33867|unclassified Euryarchaeota	28890|Euryarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_93515_1	340177.Cag_0245	6.02e-05	45.1	COG3259@1|root,COG3259@2|Bacteria,1FDQF@1090|Chlorobi	1090|Chlorobi	C	PFAM nickel-dependent hydrogenase, large subunit	-	-	1.12.1.2	ko:K00436	-	-	R00700	-	ko00000,ko01000	-	-	-	NiFeSe_Hases
k59_93515_2	552811.Dehly_0928	1.16e-54	178.0	COG1941@1|root,COG1941@2|Bacteria,2G8TW@200795|Chloroflexi	200795|Chloroflexi	C	NADH ubiquinone oxidoreductase, 20 Kd subunit	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_q6
k59_40526_1	880072.Desac_0306	4.62e-64	203.0	COG1521@1|root,COG1521@2|Bacteria,1MUYA@1224|Proteobacteria,42MVZ@68525|delta/epsilon subdivisions,2WJ3N@28221|Deltaproteobacteria,2MQTU@213462|Syntrophobacterales	28221|Deltaproteobacteria	F	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis	coaX	-	2.7.1.33	ko:K03525	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1986	Pan_kinase
k59_139247_1	765420.OSCT_1932	2.56e-40	154.0	COG0642@1|root,COG5002@1|root,COG0642@2|Bacteria,COG2205@2|Bacteria,COG5002@2|Bacteria,2G7J9@200795|Chloroflexi	200795|Chloroflexi	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA,Hpt,PAS,PAS_4,Response_reg
k59_25298_2	439235.Dalk_1964	2.38e-72	233.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,2MIQF@213118|Desulfobacterales	28221|Deltaproteobacteria	T	response regulator receiver	-	-	-	ko:K02481	-	-	-	-	ko00000,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
k59_230102_1	338966.Ppro_1852	9.4e-81	254.0	COG0469@1|root,COG0469@2|Bacteria,1MU21@1224|Proteobacteria,42N30@68525|delta/epsilon subdivisions,2WJSW@28221|Deltaproteobacteria,43T0A@69541|Desulfuromonadales	28221|Deltaproteobacteria	G	Pyruvate kinase, barrel domain	pyk	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PK,PK_C
k59_199732_2	335543.Sfum_1324	7.61e-74	234.0	COG4012@1|root,COG4012@2|Bacteria,1R94F@1224|Proteobacteria,42Q7K@68525|delta/epsilon subdivisions,2WK3Y@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM Domain of unkown function DUF1786	-	-	-	-	-	-	-	-	-	-	-	-	DUF1786
k59_169280_1	1121405.dsmv_1440	6.29e-72	236.0	COG0557@1|root,COG0557@2|Bacteria,1MUS6@1224|Proteobacteria,42NHP@68525|delta/epsilon subdivisions,2X6U1@28221|Deltaproteobacteria,2MHMI@213118|Desulfobacterales	28221|Deltaproteobacteria	K	PFAM ribonuclease II	-	-	3.1.13.1	ko:K01147,ko:K12573	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	OB_RNB,RNB,S1
k59_70689_1	388467.A19Y_4547	1.41e-77	253.0	COG0280@1|root,COG0857@1|root,COG0280@2|Bacteria,COG0857@2|Bacteria,1G16R@1117|Cyanobacteria,1H85V@1150|Oscillatoriales	1117|Cyanobacteria	C	belongs to the CobB CobQ family	pta	-	2.3.1.8	ko:K13788	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00230,R00921	RC00004,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_26,DRTGG,PTA_PTB
k59_101298_1	1121396.KB892913_gene163	7.65e-120	363.0	COG0471@1|root,COG0471@2|Bacteria,1MU0K@1224|Proteobacteria,42MR7@68525|delta/epsilon subdivisions,2WIKA@28221|Deltaproteobacteria,2MHKE@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Citrate transporter	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS,TrkA_C
k59_124157_1	179408.Osc7112_5096	9.73e-51	183.0	COG0515@1|root,COG0745@1|root,COG2203@1|root,COG3899@1|root,COG5002@1|root,COG0515@2|Bacteria,COG0745@2|Bacteria,COG2203@2|Bacteria,COG3899@2|Bacteria,COG5002@2|Bacteria,1GBKM@1117|Cyanobacteria,1H7D9@1150|Oscillatoriales	1117|Cyanobacteria	KLT	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GAF,HATPase_c,HisKA,PAS_3,Pkinase,Response_reg
k59_55849_1	439235.Dalk_0627	3.89e-23	102.0	COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,42MTX@68525|delta/epsilon subdivisions,2WITE@28221|Deltaproteobacteria,2MIIQ@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Belongs to the DegT DnrJ EryC1 family	pseC	-	2.6.1.102	ko:K13010	ko00520,map00520	-	R10460	RC00006,RC00781	ko00000,ko00001,ko01000,ko01005,ko01007	-	-	-	DegT_DnrJ_EryC1
k59_154450_1	933262.AXAM01000018_gene1014	4.45e-33	125.0	COG2006@1|root,COG2221@1|root,COG2006@2|Bacteria,COG2221@2|Bacteria,1RABP@1224|Proteobacteria,42QQA@68525|delta/epsilon subdivisions,2WMRX@28221|Deltaproteobacteria,2MK55@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF362,Fer4
k59_154450_2	202954.BBNK01000005_gene1785	5.32e-23	99.0	COG0119@1|root,COG0119@2|Bacteria,1MUMX@1224|Proteobacteria,1RMUX@1236|Gammaproteobacteria,3NJHS@468|Moraxellaceae	1236|Gammaproteobacteria	E	HMGL-like	mvaB	-	4.1.3.4	ko:K01640	ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146	M00036,M00088	R01360,R08090	RC00502,RC00503,RC01118,RC01946	ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like
k59_40556_1	1125863.JAFN01000001_gene3443	3.08e-107	318.0	COG0559@1|root,COG0559@2|Bacteria,1MU25@1224|Proteobacteria,42NUE@68525|delta/epsilon subdivisions,2WMSB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
k59_70705_1	439235.Dalk_1239	5.84e-11	60.5	COG0782@1|root,COG0782@2|Bacteria,1RCXW@1224|Proteobacteria,42SDX@68525|delta/epsilon subdivisions,2WP41@28221|Deltaproteobacteria,2MK62@213118|Desulfobacterales	28221|Deltaproteobacteria	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	-	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
k59_70705_2	879212.DespoDRAFT_02038	1.29e-19	91.3	COG0699@1|root,COG0699@2|Bacteria,1R3WJ@1224|Proteobacteria,42N0G@68525|delta/epsilon subdivisions,2WKFJ@28221|Deltaproteobacteria,2MJ5I@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Dynamin family	-	-	-	-	-	-	-	-	-	-	-	-	Dynamin_N
k59_214760_1	335543.Sfum_2562	4.71e-60	207.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1MU0R@1224|Proteobacteria,42NDJ@68525|delta/epsilon subdivisions,2WJSH@28221|Deltaproteobacteria,2MQB6@213462|Syntrophobacterales	28221|Deltaproteobacteria	G	Belongs to the PEP-utilizing enzyme family	ppdK	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
k59_63390_1	1009370.ALO_18170	6.21e-38	146.0	COG0744@1|root,COG0744@2|Bacteria,1TPM5@1239|Firmicutes,4H360@909932|Negativicutes	909932|Negativicutes	M	Penicillin-binding Protein	pbpD	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
k59_10310_1	1157490.EL26_15380	5.09e-48	163.0	COG0351@1|root,COG0351@2|Bacteria,1TQ4A@1239|Firmicutes,4HAAH@91061|Bacilli,2786M@186823|Alicyclobacillaceae	91061|Bacilli	H	Phosphomethylpyrimidine kinase	thiD	-	2.7.1.49,2.7.4.7	ko:K00941	ko00730,ko01100,map00730,map01100	M00127	R03471,R04509	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Phos_pyr_kin
k59_17576_1	1115515.EV102420_12_00990	2.38e-11	69.7	COG1196@1|root,COG3264@1|root,COG1196@2|Bacteria,COG3264@2|Bacteria,1MWSA@1224|Proteobacteria,1RMYY@1236|Gammaproteobacteria,3XMHD@561|Escherichia	1236|Gammaproteobacteria	DM	Mechanosensitive channel that opens in response to membrane tension and specific ionic conditions. Requires high concentrations of external K( ), NH(4)( ), Rb( ) or Cs( ) to gate. May participate in the regulation of osmotic pressure changes within the cell, although it does not appear to have a major role in osmolarity regulation. Forms an ion channel of 1.0 nanosiemens conductance. The channel can remain active for between 30 seconds and over 3 minutes	kefA	GO:0005575,GO:0005623,GO:0005886,GO:0006884,GO:0008150,GO:0008361,GO:0009987,GO:0009992,GO:0016020,GO:0016043,GO:0019725,GO:0030104,GO:0032535,GO:0042592,GO:0044464,GO:0048878,GO:0055082,GO:0065007,GO:0065008,GO:0071840,GO:0071944,GO:0090066	-	ko:K05802,ko:K22051	-	-	-	-	ko00000,ko02000	1.A.23.1.1,1.A.23.1.2,1.A.23.1.3	-	-	MS_channel,MscS_TM,MscS_porin
k59_63397_1	1121405.dsmv_1308	6.9e-68	214.0	COG1309@1|root,COG1309@2|Bacteria,1R7QV@1224|Proteobacteria,43AFI@68525|delta/epsilon subdivisions,2WINE@28221|Deltaproteobacteria,2MJ31@213118|Desulfobacterales	28221|Deltaproteobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
k59_78613_1	398767.Glov_3716	1.81e-39	146.0	COG4584@1|root,COG4584@2|Bacteria,1MU2G@1224|Proteobacteria,42N2X@68525|delta/epsilon subdivisions,2X7GJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	Sigma-70, region 4	-	-	-	-	-	-	-	-	-	-	-	-	rve
k59_78613_2	1182590.BN5_02221	5.9e-48	161.0	COG1484@1|root,COG1484@2|Bacteria,1MVU2@1224|Proteobacteria,1RNUA@1236|Gammaproteobacteria,1YE8I@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	L	IstB-like ATP binding protein	istB3	-	-	-	-	-	-	-	-	-	-	-	IstB_IS21,IstB_IS21_ATP
k59_207407_1	742818.HMPREF9451_00313	8.82e-19	90.1	COG2223@1|root,COG2223@2|Bacteria,2I2RR@201174|Actinobacteria,4CYKJ@84998|Coriobacteriia	84998|Coriobacteriia	P	Major Facilitator Superfamily	-	-	-	ko:K08177	-	-	-	-	ko00000,ko02000	2.A.1.11	-	-	MFS_1
k59_207409_2	767029.HMPREF9154_1565	0.000334	43.5	COG1716@1|root,COG1716@2|Bacteria,2GK99@201174|Actinobacteria	201174|Actinobacteria	T	(FHA) domain	garA	-	-	-	-	-	-	-	-	-	-	-	FHA,Yop-YscD_cpl,zinc_ribbon_2
k59_2433_2	247490.KSU1_D0297	6.36e-22	95.5	COG0438@1|root,COG0438@2|Bacteria,2J10U@203682|Planctomycetes	203682|Planctomycetes	M	Glycosyl transferase 4-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
k59_154474_1	742735.HMPREF9467_00844	4.73e-11	67.8	2BZV6@1|root,33KK7@2|Bacteria,1V00S@1239|Firmicutes,24DEM@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_207412_1	644107.SL1157_0208	3.79e-07	52.8	COG0824@1|root,COG0824@2|Bacteria,1MZH6@1224|Proteobacteria,2UBYM@28211|Alphaproteobacteria,4NC4G@97050|Ruegeria	28211|Alphaproteobacteria	S	Tol-pal system-associated acyl-CoA thioesterase	ybgC	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT
k59_222646_1	411459.RUMOBE_02481	1.32e-41	147.0	COG3640@1|root,COG3640@2|Bacteria,1V308@1239|Firmicutes,24H11@186801|Clostridia	186801|Clostridia	D	CobQ/CobB/MinD/ParA nucleotide binding domain	-	-	-	ko:K07321	-	-	-	-	ko00000	-	-	-	CbiA
k59_25338_1	335543.Sfum_1404	1.71e-78	254.0	COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,42MQS@68525|delta/epsilon subdivisions,2WINP@28221|Deltaproteobacteria,2MR0I@213462|Syntrophobacterales	28221|Deltaproteobacteria	I	PFAM Enoyl-CoA hydratase isomerase	-	-	1.1.1.35,4.2.1.17,5.1.2.3,5.3.3.8	ko:K01782,ko:K01825	ko00071,ko00280,ko00281,ko00310,ko00362,ko00380,ko00410,ko00640,ko00650,ko00903,ko00930,ko01040,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00071,map00280,map00281,map00310,map00362,map00380,map00410,map00640,map00650,map00903,map00930,map01040,map01100,map01110,map01120,map01130,map01200,map01212	M00032,M00087	R01975,R03026,R03045,R03276,R04137,R04170,R04203,R04204,R04224,R04737,R04738,R04739,R04740,R04741,R04744,R04745,R04746,R04748,R04749,R04756,R05066,R05305,R06411,R06412,R06941,R06942,R07935,R07951,R08093,R08094	RC00029,RC00099,RC00117,RC00241,RC00525,RC00831,RC00834,RC00896,RC01078,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	3HCDH,3HCDH_N,ECH_1
k59_101334_1	933262.AXAM01000010_gene1377	2.38e-16	79.7	COG1680@1|root,COG1680@2|Bacteria,1QUYZ@1224|Proteobacteria,42PUC@68525|delta/epsilon subdivisions,2WK0V@28221|Deltaproteobacteria,2MIWD@213118|Desulfobacterales	28221|Deltaproteobacteria	V	PFAM Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
k59_101334_2	1463926.JOCA01000001_gene4262	6.72e-16	77.8	COG1619@1|root,COG1619@2|Bacteria,2I358@201174|Actinobacteria	201174|Actinobacteria	V	peptidase U61	-	-	3.4.17.13	ko:K01297	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_S66
k59_40577_1	439235.Dalk_0447	3.18e-46	163.0	COG3366@1|root,COG3366@2|Bacteria,1NEIQ@1224|Proteobacteria,42P9X@68525|delta/epsilon subdivisions,2WM1E@28221|Deltaproteobacteria,2MHVZ@213118|Desulfobacterales	28221|Deltaproteobacteria	S	PFAM Nucleoside recognition	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_154476_1	706587.Desti_0760	3.25e-69	224.0	COG0025@1|root,COG0025@2|Bacteria,1REWR@1224|Proteobacteria,437JE@68525|delta/epsilon subdivisions,2X2TE@28221|Deltaproteobacteria,2MQZ0@213462|Syntrophobacterales	28221|Deltaproteobacteria	P	PFAM sodium hydrogen exchanger	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
k59_63410_1	330214.NIDE3284	1.2e-11	75.1	COG3829@1|root,COG4191@1|root,COG5000@1|root,COG3829@2|Bacteria,COG4191@2|Bacteria,COG5000@2|Bacteria,3J117@40117|Nitrospirae	40117|Nitrospirae	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF3365,HAMP,HATPase_c,HisKA,PAS_4
k59_146608_1	1265505.ATUG01000002_gene1613	5.03e-62	213.0	COG2204@1|root,COG3829@1|root,COG2204@2|Bacteria,COG3829@2|Bacteria,1MU0N@1224|Proteobacteria,43CWU@68525|delta/epsilon subdivisions	1224|Proteobacteria	T	Bacterial regulatory protein, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
k59_101342_1	102129.Lepto7375DRAFT_5092	3.38e-17	84.0	COG0608@1|root,COG0608@2|Bacteria,1G0QE@1117|Cyanobacteria,1H709@1150|Oscillatoriales	1117|Cyanobacteria	L	single-stranded-DNA-specific exonuclease RecJ	recJ	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
k59_239044_1	96561.Dole_2243	4.08e-44	155.0	COG1104@1|root,COG1104@2|Bacteria,1MU1C@1224|Proteobacteria,42M5V@68525|delta/epsilon subdivisions,2WIR6@28221|Deltaproteobacteria,2MHV8@213118|Desulfobacterales	28221|Deltaproteobacteria	H	aminotransferase class V	-	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
k59_141209_1	237368.SCABRO_02415	2.26e-67	216.0	COG0598@1|root,COG0598@2|Bacteria,2IX61@203682|Planctomycetes	203682|Planctomycetes	P	Mediates influx of magnesium ions	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
k59_3724_1	102129.Lepto7375DRAFT_0252	7.43e-22	95.1	COG5433@1|root,COG5433@2|Bacteria,1G2IT@1117|Cyanobacteria,1HHU1@1150|Oscillatoriales	1117|Cyanobacteria	L	IMG reference gene	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
k59_209463_1	1304885.AUEY01000022_gene3403	1.38e-135	399.0	COG0498@1|root,COG0498@2|Bacteria,1MUWQ@1224|Proteobacteria,42M1W@68525|delta/epsilon subdivisions,2WK53@28221|Deltaproteobacteria,2MIJV@213118|Desulfobacterales	28221|Deltaproteobacteria	E	TIGRFAM threonine synthase	thrC	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
k59_232256_1	933262.AXAM01000016_gene188	3.17e-44	163.0	COG3225@1|root,COG3225@2|Bacteria,1MY63@1224|Proteobacteria,42N95@68525|delta/epsilon subdivisions,2WJ0N@28221|Deltaproteobacteria,2MIKM@213118|Desulfobacterales	28221|Deltaproteobacteria	N	ABC-type uncharacterized transport system	-	-	-	-	-	-	-	-	-	-	-	-	ABC_transp_aux
k59_117732_1	665942.HMPREF1022_03100	7.21e-16	71.2	COG1146@1|root,COG1146@2|Bacteria,1QWQ4@1224|Proteobacteria,43BUY@68525|delta/epsilon subdivisions,2X75X@28221|Deltaproteobacteria,2MHB0@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_7
k59_95522_1	1379698.RBG1_1C00001G1222	3.96e-11	58.2	COG4892@1|root,COG4892@2|Bacteria	2|Bacteria	S	Cytochrome b5-like Heme/Steroid binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Cyt-b5
k59_95522_2	1229172.JQFA01000002_gene4947	7.07e-57	184.0	COG1215@1|root,COG1215@2|Bacteria,1GDJY@1117|Cyanobacteria,1H8JX@1150|Oscillatoriales	1117|Cyanobacteria	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
k59_178372_1	886293.Sinac_6086	1.85e-36	134.0	COG0174@1|root,COG0174@2|Bacteria,2IXHM@203682|Planctomycetes	203682|Planctomycetes	E	glutamine synthetase	-	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
k59_58169_1	593750.Metfor_2917	2.23e-06	56.6	COG0642@1|root,COG2203@1|root,arCOG02348@1|root,arCOG02349@1|root,arCOG02352@1|root,arCOG02376@1|root,arCOG02385@1|root,arCOG02348@2157|Archaea,arCOG02349@2157|Archaea,arCOG02352@2157|Archaea,arCOG02369@2157|Archaea,arCOG02376@2157|Archaea,arCOG02385@2157|Archaea,arCOG06193@2157|Archaea,2Y7U3@28890|Euryarchaeota,2NAXF@224756|Methanomicrobia	224756|Methanomicrobia	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,PAS,PAS_3,PAS_9,Response_reg
k59_73269_1	1094980.Mpsy_1130	7.06e-19	82.4	COG0097@1|root,arCOG04090@2157|Archaea,2XTIS@28890|Euryarchaeota,2N9KP@224756|Methanomicrobia	224756|Methanomicrobia	J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center	rpl6	-	-	ko:K02933	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L6
k59_73269_2	136037.KDR21989	1.29e-16	77.0	COG1717@1|root,KOG0878@2759|Eukaryota,3A0DJ@33154|Opisthokonta,3BPE5@33208|Metazoa,3D6EA@33213|Bilateria,41YXQ@6656|Arthropoda,3SM9H@50557|Insecta	33208|Metazoa	J	Structural constituent of ribosome. It is involved in the biological process described with	RPL32	GO:0000184,GO:0000956,GO:0001889,GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005730,GO:0005737,GO:0005783,GO:0005789,GO:0005791,GO:0005829,GO:0005840,GO:0005844,GO:0006139,GO:0006401,GO:0006402,GO:0006412,GO:0006413,GO:0006518,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006725,GO:0006807,GO:0006810,GO:0006886,GO:0007275,GO:0008104,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009410,GO:0009719,GO:0009725,GO:0009892,GO:0009987,GO:0010033,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0012505,GO:0014070,GO:0015031,GO:0015833,GO:0015934,GO:0016020,GO:0016070,GO:0016071,GO:0019222,GO:0019439,GO:0019538,GO:0022625,GO:0022626,GO:0030867,GO:0031090,GO:0031099,GO:0031100,GO:0031960,GO:0031974,GO:0031981,GO:0031984,GO:0032501,GO:0032502,GO:0032870,GO:0032991,GO:0033036,GO:0033365,GO:0033993,GO:0034613,GO:0034641,GO:0034645,GO:0034655,GO:0035690,GO:0042175,GO:0042221,GO:0042493,GO:0042788,GO:0042886,GO:0043043,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044267,GO:0044270,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044425,GO:0044428,GO:0044432,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045047,GO:0045184,GO:0046483,GO:0046700,GO:0046907,GO:0048513,GO:0048519,GO:0048545,GO:0048731,GO:0048732,GO:0048856,GO:0050789,GO:0050896,GO:0051179,GO:0051234,GO:0051384,GO:0051641,GO:0051649,GO:0051716,GO:0060255,GO:0061008,GO:0065007,GO:0070013,GO:0070727,GO:0070887,GO:0070972,GO:0071310,GO:0071383,GO:0071384,GO:0071385,GO:0071396,GO:0071407,GO:0071466,GO:0071495,GO:0071548,GO:0071549,GO:0071702,GO:0071704,GO:0071705,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:0090304,GO:0097327,GO:0097421,GO:0098552,GO:0098554,GO:0098556,GO:0098562,GO:0098588,GO:0098827,GO:1901360,GO:1901361,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901654,GO:1901655,GO:1901700,GO:1901701,GO:1990904	-	ko:K02912	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L32e
k59_42254_1	1173020.Cha6605_4495	2.05e-177	513.0	COG5659@1|root,COG5659@2|Bacteria	2|Bacteria	L	transposition	-	-	-	-	-	-	-	-	-	-	-	-	DDE_5
k59_239425_1	338963.Pcar_1418	2.39e-92	290.0	COG0441@1|root,COG0441@2|Bacteria,1MUP2@1224|Proteobacteria,42M20@68525|delta/epsilon subdivisions,2WJ2N@28221|Deltaproteobacteria,43S1X@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Threonyl and Alanyl tRNA synthetase second additional domain	thrS	GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD
k59_35391_1	457421.CBFG_00838	7.6e-27	110.0	COG1679@1|root,COG1679@2|Bacteria,1UJDG@1239|Firmicutes,24DTH@186801|Clostridia,26AXI@186813|unclassified Clostridiales	186801|Clostridia	S	Protein of unknown function (DUF521)	-	-	-	ko:K09123	-	-	-	-	ko00000	-	-	-	DUF521
k59_133939_1	1449351.RISW2_13375	3.73e-31	126.0	COG0178@1|root,COG0178@2|Bacteria,1MW0W@1224|Proteobacteria,2TQK9@28211|Alphaproteobacteria,4KKNK@93682|Roseivivax	28211|Alphaproteobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
k59_118073_1	1232410.KI421422_gene2071	3.63e-69	232.0	COG0542@1|root,COG0542@2|Bacteria,1MURH@1224|Proteobacteria,42M9S@68525|delta/epsilon subdivisions,2WJSZ@28221|Deltaproteobacteria,43S73@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
k59_80899_1	1088721.NSU_4947	2.37e-58	191.0	COG2801@1|root,COG2801@2|Bacteria,1MVC8@1224|Proteobacteria,2TRX0@28211|Alphaproteobacteria,2K3CJ@204457|Sphingomonadales	204457|Sphingomonadales	L	Integrase core domain	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve
k59_95884_1	1121405.dsmv_0078	6.37e-149	437.0	COG0443@1|root,COG0443@2|Bacteria,1MVEN@1224|Proteobacteria,42M64@68525|delta/epsilon subdivisions,2WIWS@28221|Deltaproteobacteria,2MJ2X@213118|Desulfobacterales	28221|Deltaproteobacteria	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
k59_193888_1	690850.Desaf_0690	2.07e-12	64.7	COG4388@1|root,COG4388@2|Bacteria,1QZFH@1224|Proteobacteria,43D9A@68525|delta/epsilon subdivisions,2X8FY@28221|Deltaproteobacteria,2MHHZ@213115|Desulfovibrionales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_224378_1	95619.PM1_0222110	9.08e-100	304.0	COG1271@1|root,COG1271@2|Bacteria,1MV60@1224|Proteobacteria,1RN2U@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	oxidase, subunit	cydA	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016679,GO:0019646,GO:0020037,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046906,GO:0048037,GO:0055114,GO:0070069,GO:0071944,GO:0097159,GO:1901363	1.10.3.14	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	iPC815.YPO1117,iSFxv_1172.SFxv_0621,iS_1188.S0577	Cyt_bd_oxida_I
k59_42266_1	1105031.HMPREF1141_0275	3.64e-63	211.0	COG2804@1|root,COG2804@2|Bacteria,1TPGE@1239|Firmicutes,247KA@186801|Clostridia,36DG2@31979|Clostridiaceae	186801|Clostridia	NU	type II secretion system protein E	xcpR	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE,T2SSE_N
k59_224382_1	1121405.dsmv_3317	7.03e-192	545.0	COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,42MEA@68525|delta/epsilon subdivisions,2WIW6@28221|Deltaproteobacteria,2MI74@213118|Desulfobacterales	28221|Deltaproteobacteria	KT	Sigma-54 interaction domain	-	-	2.1.1.80	ko:K00575	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	HTH_8,PAS_4,PAS_9,Sigma54_activat
k59_42272_1	935866.JAER01000012_gene3549	1.57e-35	136.0	COG1233@1|root,COG1233@2|Bacteria,2HZ9J@201174|Actinobacteria,4DRF3@85009|Propionibacteriales	201174|Actinobacteria	Q	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
k59_232764_1	706587.Desti_1351	1.49e-81	249.0	COG0438@1|root,COG0438@2|Bacteria,1RA8H@1224|Proteobacteria,42RMM@68525|delta/epsilon subdivisions,2WNQY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_118085_1	631454.N177_1638	7.49e-65	213.0	COG1053@1|root,COG1053@2|Bacteria,1MX5A@1224|Proteobacteria,2TV7T@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	COG1053 Succinate dehydrogenase fumarate reductase flavoprotein subunit	cobZ	-	-	ko:K13796	-	-	-	-	ko00000	-	-	-	FAD_binding_2
k59_95901_1	1121887.AUDK01000017_gene82	3.38e-40	138.0	COG0338@1|root,COG0338@2|Bacteria	2|Bacteria	L	D12 class N6 adenine-specific DNA methyltransferase	dmnB	-	2.1.1.72	ko:K06223	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko02048,ko03032,ko03400	-	-	-	Dam,MethyltransfD12
k59_19761_1	335543.Sfum_1857	2.93e-50	166.0	COG2203@1|root,COG2203@2|Bacteria,1R8AK@1224|Proteobacteria,42MTP@68525|delta/epsilon subdivisions,2WIST@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	PFAM GAF domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2
k59_224387_1	1345023.M467_14105	2.49e-23	100.0	COG2264@1|root,COG2264@2|Bacteria,1TPKI@1239|Firmicutes,4HAMF@91061|Bacilli,3WE34@539002|Bacillales incertae sedis	91061|Bacilli	J	Ribosomal protein L11 methyltransferase	prmA	-	-	ko:K02687	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PrmA
k59_19764_1	335543.Sfum_1977	9.97e-65	223.0	COG1148@1|root,COG1148@2|Bacteria,1QUM4@1224|Proteobacteria,42MPP@68525|delta/epsilon subdivisions,2WJ3U@28221|Deltaproteobacteria,2MQTI@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_4,Fer4_7,Pyr_redox_2
k59_118091_1	335543.Sfum_0928	3.09e-46	164.0	COG0389@1|root,COG0389@2|Bacteria,1RBTJ@1224|Proteobacteria,42QY9@68525|delta/epsilon subdivisions,2WMTI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	PFAM UMUC domain protein DNA-repair protein	-	-	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C
k59_12824_1	335543.Sfum_0098	3.83e-93	295.0	COG0466@1|root,COG0466@2|Bacteria,1MUV2@1224|Proteobacteria,42M9W@68525|delta/epsilon subdivisions,2WJ29@28221|Deltaproteobacteria,2MQZP@213462|Syntrophobacterales	28221|Deltaproteobacteria	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon-2	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
k59_58201_1	96561.Dole_0647	1.39e-150	443.0	COG0661@1|root,COG0661@2|Bacteria,1MU1Z@1224|Proteobacteria,42N87@68525|delta/epsilon subdivisions,2WK1B@28221|Deltaproteobacteria,2MHU5@213118|Desulfobacterales	28221|Deltaproteobacteria	S	pfam abc-1	-	-	-	ko:K03688	-	-	-	-	ko00000	-	-	-	ABC1,APH
k59_224389_1	1340493.JNIF01000003_gene3040	8.37e-44	148.0	COG3293@1|root,COG3293@2|Bacteria,3Y7X8@57723|Acidobacteria	57723|Acidobacteria	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_2
k59_193907_1	640081.Dsui_2953	3.68e-10	66.2	COG0834@1|root,COG2199@1|root,COG0834@2|Bacteria,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,2WH96@28216|Betaproteobacteria,2KZY4@206389|Rhodocyclales	206389|Rhodocyclales	T	Bacterial periplasmic substrate-binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,SBP_bac_3
k59_202141_2	1121396.KB892913_gene116	3.83e-32	125.0	COG0517@1|root,COG0517@2|Bacteria,1MXI6@1224|Proteobacteria,42WI2@68525|delta/epsilon subdivisions,2WRPD@28221|Deltaproteobacteria,2MQ18@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Transposase zinc-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Y2_Tnp,Zn_Tnp_IS91
k59_133971_1	690850.Desaf_2573	1.57e-148	430.0	COG3119@1|root,COG3119@2|Bacteria,1MUJH@1224|Proteobacteria,42Q8I@68525|delta/epsilon subdivisions,2X5IX@28221|Deltaproteobacteria,2MA7R@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	Sulfatase	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase,Sulfatase_C
k59_88102_1	10029.XP_007634688.1	8.66e-77	250.0	COG2036@1|root,COG5262@1|root,KOG1745@2759|Eukaryota,KOG1756@2759|Eukaryota,39ZTV@33154|Opisthokonta,3BPDH@33208|Metazoa,3D6BK@33213|Bilateria,48E1W@7711|Chordata,49B7M@7742|Vertebrata,3JGKY@40674|Mammalia,35PSM@314146|Euarchontoglires,4Q54X@9989|Rodentia	33208|Metazoa	B	Core histone H2A/H2B/H3/H4	HIST3H3	GO:0000228,GO:0000723,GO:0000726,GO:0000785,GO:0000786,GO:0000788,GO:0000790,GO:0003674,GO:0003676,GO:0003677,GO:0003682,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005694,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006303,GO:0006323,GO:0006325,GO:0006333,GO:0006334,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016233,GO:0022607,GO:0031333,GO:0031490,GO:0031491,GO:0031492,GO:0031497,GO:0031974,GO:0031981,GO:0032200,GO:0032459,GO:0032460,GO:0032991,GO:0032993,GO:0033554,GO:0034622,GO:0034641,GO:0034728,GO:0042592,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043254,GO:0043933,GO:0044085,GO:0044087,GO:0044237,GO:0044238,GO:0044260,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044446,GO:0044454,GO:0044464,GO:0044815,GO:0044877,GO:0046483,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051129,GO:0051259,GO:0051262,GO:0051276,GO:0051290,GO:0051291,GO:0051716,GO:0060249,GO:0065003,GO:0065004,GO:0065007,GO:0065008,GO:0070013,GO:0071103,GO:0071704,GO:0071824,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363	-	ko:K11253,ko:K11275	ko05034,ko05202,ko05322,map05034,map05202,map05322	-	-	-	ko00000,ko00001,ko03036,ko04147	-	-	-	Histone
k59_193910_1	909663.KI867149_gene3386	3.3e-62	196.0	2DBU2@1|root,2ZB3S@2|Bacteria,1N1MT@1224|Proteobacteria,42VJX@68525|delta/epsilon subdivisions,2WSPP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_4
k59_35426_1	472759.Nhal_1238	8e-105	316.0	COG1215@1|root,COG1215@2|Bacteria,1MW1E@1224|Proteobacteria,1RZY2@1236|Gammaproteobacteria,1X091@135613|Chromatiales	135613|Chromatiales	M	Glycosyl transferase family 21	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3
k59_88105_1	1125863.JAFN01000001_gene2312	6.84e-38	139.0	COG5653@1|root,COG5653@2|Bacteria	2|Bacteria	M	Protein involved in cellulose biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_6
k59_42287_1	335543.Sfum_0721	4.79e-105	315.0	COG0010@1|root,COG0010@2|Bacteria,1MVFH@1224|Proteobacteria,42NBC@68525|delta/epsilon subdivisions,2WIMR@28221|Deltaproteobacteria,2MRRB@213462|Syntrophobacterales	28221|Deltaproteobacteria	E	Belongs to the arginase family	speB	-	3.5.3.1,3.5.3.11	ko:K01476,ko:K01480	ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146	M00029,M00133,M00134	R00551,R01157	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
k59_95919_1	177437.HRM2_24580	1.27e-46	164.0	COG0477@1|root,COG2814@2|Bacteria,1MX2Q@1224|Proteobacteria,43BTD@68525|delta/epsilon subdivisions,2X745@28221|Deltaproteobacteria,2MJEE@213118|Desulfobacterales	28221|Deltaproteobacteria	EGP	Major Facilitator Superfamily	-	-	-	ko:K03446	-	M00701	-	-	ko00000,ko00002,ko02000	2.A.1.3	-	-	MFS_1
k59_95919_2	489825.LYNGBM3L_36000	1.17e-07	51.6	COG1672@1|root,COG1672@2|Bacteria,1G871@1117|Cyanobacteria,1HHDP@1150|Oscillatoriales	1117|Cyanobacteria	S	Electron transfer DM13	-	-	-	-	-	-	-	-	-	-	-	-	DM13
k59_27090_1	1123228.AUIH01000010_gene3993	5.32e-34	132.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,1RMMJ@1236|Gammaproteobacteria,1XI78@135619|Oceanospirillales	135619|Oceanospirillales	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
k59_58216_1	313606.M23134_06138	4.99e-06	55.8	COG2931@1|root,COG3203@1|root,COG5306@1|root,COG2931@2|Bacteria,COG3203@2|Bacteria,COG5306@2|Bacteria,4PM6S@976|Bacteroidetes,47Y33@768503|Cytophagia	976|Bacteroidetes	M	FG-GAP repeat	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP_2
k59_42291_1	96561.Dole_2306	3.74e-67	213.0	COG0336@1|root,COG0336@2|Bacteria,1MUN1@1224|Proteobacteria,42P8R@68525|delta/epsilon subdivisions,2WKIR@28221|Deltaproteobacteria,2MIUI@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Belongs to the RNA methyltransferase TrmD family	trmD	GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	Methyltrn_RNA_4,tRNA_m1G_MT
k59_27095_1	1177154.Y5S_01704	8.73e-70	241.0	COG1361@1|root,COG4932@1|root,COG1361@2|Bacteria,COG4932@2|Bacteria,1R5G4@1224|Proteobacteria,1SEWA@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Domain of unknown function DUF11	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,SdrD_B
k59_232792_1	314230.DSM3645_29461	1.2e-27	113.0	COG2855@1|root,COG2855@2|Bacteria,2IX2B@203682|Planctomycetes	203682|Planctomycetes	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	Cons_hypoth698
k59_209832_1	1121447.JONL01000002_gene2004	1.57e-83	261.0	COG5476@1|root,COG5476@2|Bacteria,1MX4P@1224|Proteobacteria	1224|Proteobacteria	J	Involved in peptidolytic degradation of cyclic heptapeptide hepatotoxin microcystin (MC)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1485,MlrC_C
k59_178800_1	335543.Sfum_1863	3.55e-106	311.0	COG1611@1|root,COG1611@2|Bacteria,1MU6N@1224|Proteobacteria,42P56@68525|delta/epsilon subdivisions,2WK5J@28221|Deltaproteobacteria,2MQ5V@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Possible lysine decarboxylase	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
k59_156766_1	1230476.C207_00518	6.55e-24	110.0	COG0457@1|root,COG2114@1|root,COG5616@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,2TRUI@28211|Alphaproteobacteria,3JR8W@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	T	Adenylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,Guanylate_cyc,Trans_reg_C
k59_163768_1	1121405.dsmv_3105	2.7e-114	331.0	COG0740@1|root,COG0740@2|Bacteria,1MV46@1224|Proteobacteria,42MFU@68525|delta/epsilon subdivisions,2WK74@28221|Deltaproteobacteria,2MJ0K@213118|Desulfobacterales	28221|Deltaproteobacteria	O	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
k59_134004_1	32057.KB217478_gene7264	1.85e-06	57.4	COG0643@1|root,COG0643@2|Bacteria,1G26V@1117|Cyanobacteria	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt
k59_88122_1	1173020.Cha6605_3406	2.43e-35	129.0	COG1234@1|root,COG1234@2|Bacteria,1G1SW@1117|Cyanobacteria	1117|Cyanobacteria	L	PFAM Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_4,HTH_Tnp_4
k59_88122_2	1173020.Cha6605_1673	1.18e-28	111.0	COG1234@1|root,COG1234@2|Bacteria,1G1SW@1117|Cyanobacteria	1117|Cyanobacteria	L	PFAM Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_4,HTH_Tnp_4
k59_141575_1	580340.Tlie_1312	1.5e-50	175.0	COG3199@1|root,COG3199@2|Bacteria,3T9RA@508458|Synergistetes	508458|Synergistetes	H	PFAM ATP-NAD AcoX kinase	-	-	-	-	-	-	-	-	-	-	-	-	NAD_kinase
k59_134010_1	644282.Deba_0243	1.17e-77	249.0	COG2069@1|root,COG2069@2|Bacteria,1QS8G@1224|Proteobacteria,437H2@68525|delta/epsilon subdivisions,2WKVX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM CO dehydrogenase acetyl-CoA synthase delta subunit	-	-	2.1.1.245	ko:K00194	ko00680,ko00720,ko01120,ko01200,map00680,map00720,map01120,map01200	M00357,M00377,M00422	R09096,R10219,R10243	RC00004,RC00113,RC02977	ko00000,ko00001,ko00002,ko01000	-	-	-	CdhD
k59_111146_1	335543.Sfum_0458	3.93e-85	267.0	COG1884@1|root,COG1884@2|Bacteria,1MUXX@1224|Proteobacteria,42P03@68525|delta/epsilon subdivisions,2WIPY@28221|Deltaproteobacteria,2MR53@213462|Syntrophobacterales	28221|Deltaproteobacteria	I	PFAM Methylmalonyl-CoA mutase	-	-	5.4.99.2	ko:K01848	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
k59_178813_1	637389.Acaty_c2070	1.02e-38	139.0	COG2854@1|root,COG2854@2|Bacteria,1N275@1224|Proteobacteria,1SB2V@1236|Gammaproteobacteria,2NCVH@225057|Acidithiobacillales	225057|Acidithiobacillales	Q	membrane protein HpnM	-	-	-	ko:K07323	ko02010,map02010	M00210	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27.3	-	-	MlaC
k59_224424_1	439235.Dalk_5205	9.34e-38	139.0	COG2807@1|root,COG2807@2|Bacteria,1QW3Y@1224|Proteobacteria,42MUB@68525|delta/epsilon subdivisions,2WIX2@28221|Deltaproteobacteria,2MJ4V@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Major facilitator superfamily	-	-	-	ko:K08218	ko01501,map01501	M00628	-	-	ko00000,ko00001,ko00002,ko02000	2.A.1.25	-	-	MFS_1
k59_88128_2	1304875.JAFZ01000001_gene823	1.96e-74	235.0	COG0477@1|root,COG2814@2|Bacteria,3TACG@508458|Synergistetes	508458|Synergistetes	EGP	PFAM Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
k59_118109_3	96561.Dole_2319	1.41e-28	105.0	COG1359@1|root,COG1359@2|Bacteria,1NGPW@1224|Proteobacteria,42TXG@68525|delta/epsilon subdivisions,2WQI4@28221|Deltaproteobacteria,2MKN6@213118|Desulfobacterales	28221|Deltaproteobacteria	S	PFAM Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	ABM
k59_187298_1	1121413.JMKT01000008_gene1659	8.01e-19	85.5	COG0664@1|root,COG0664@2|Bacteria,1QZ42@1224|Proteobacteria,42XK7@68525|delta/epsilon subdivisions,2WSIV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	PFAM Cyclic nucleotide-binding	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
k59_187298_2	1008459.TASI_1342	6.68e-25	103.0	COG0621@1|root,COG0621@2|Bacteria,1MURS@1224|Proteobacteria,2VHQM@28216|Betaproteobacteria,3T2I4@506|Alcaligenaceae	28216|Betaproteobacteria	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
k59_239466_1	335543.Sfum_3273	1.06e-64	206.0	COG0500@1|root,COG2226@2|Bacteria,1MX8I@1224|Proteobacteria,42P2Z@68525|delta/epsilon subdivisions,2WNJ6@28221|Deltaproteobacteria,2MRA3@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2)	ubiE	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
k59_50055_1	335543.Sfum_2686	1.97e-75	233.0	COG0190@1|root,COG0190@2|Bacteria,1MWU4@1224|Proteobacteria,42MW0@68525|delta/epsilon subdivisions,2WJ90@28221|Deltaproteobacteria,2MQ6N@213462|Syntrophobacterales	28221|Deltaproteobacteria	F	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	-	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
k59_208508_1	1056512.D515_00989	2.26e-47	157.0	COG3439@1|root,COG3439@2|Bacteria,1MZ38@1224|Proteobacteria,1S60I@1236|Gammaproteobacteria,1XY3V@135623|Vibrionales	135623|Vibrionales	S	Domain of unknown function DUF302	-	-	-	-	-	-	-	-	-	-	-	-	DUF302
k59_208508_2	236097.ADG881_723	1.94e-31	111.0	COG0361@1|root,COG0361@2|Bacteria,1MZFU@1224|Proteobacteria,1S8WZ@1236|Gammaproteobacteria,1XKHQ@135619|Oceanospirillales	135619|Oceanospirillales	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	-	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
k59_238453_1	90675.XP_010416767.1	3.85e-30	123.0	COG0486@1|root,KOG1191@2759|Eukaryota,37KHP@33090|Viridiplantae,3GB6H@35493|Streptophyta,3HSG6@3699|Brassicales	35493|Streptophyta	J	Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin- like GTPase superfamily. TrmE GTPase family	-	-	-	ko:K03650	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko01000,ko03016	-	-	-	MMR_HSR1,MnmE_helical,TrmE_N
k59_18481_1	926692.AZYG01000085_gene856	2.09e-56	189.0	COG2801@1|root,COG2801@2|Bacteria,1TU21@1239|Firmicutes,249HN@186801|Clostridia,3WA8E@53433|Halanaerobiales	186801|Clostridia	L	Integrase catalytic region	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve
k59_215685_1	96561.Dole_0602	3.54e-40	144.0	COG0224@1|root,COG0224@2|Bacteria,1MU28@1224|Proteobacteria,42N8B@68525|delta/epsilon subdivisions,2WJ6I@28221|Deltaproteobacteria,2MIR3@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	-	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
k59_132551_1	292459.STH704	3.57e-38	142.0	COG1022@1|root,COG1022@2|Bacteria,1V0YG@1239|Firmicutes,25E9H@186801|Clostridia	186801|Clostridia	I	AMP-binding enzyme	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
k59_132551_2	644282.Deba_1011	2.08e-107	316.0	COG0411@1|root,COG0411@2|Bacteria,1MUTY@1224|Proteobacteria,42NI5@68525|delta/epsilon subdivisions,2WIN8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	PFAM ABC transporter	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
k59_116927_1	515635.Dtur_0279	4.34e-49	164.0	COG0716@1|root,COG0716@2|Bacteria	2|Bacteria	C	FMN binding	-	-	-	-	-	-	-	-	-	-	-	-	Flavodoxin_4
k59_116927_2	1121396.KB893080_gene888	6.19e-89	262.0	COG1917@1|root,COG1917@2|Bacteria,1RH1V@1224|Proteobacteria,42U9N@68525|delta/epsilon subdivisions,2WUT7@28221|Deltaproteobacteria,2MNKF@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Cupin	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
k59_48889_1	909663.KI867150_gene967	1.85e-24	94.7	COG1837@1|root,COG1837@2|Bacteria,1N7IX@1224|Proteobacteria,42TXI@68525|delta/epsilon subdivisions,2WQBS@28221|Deltaproteobacteria,2MQIW@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	KH domain	-	-	-	ko:K06960	-	-	-	-	ko00000	-	-	-	KH_4
k59_223389_1	395961.Cyan7425_3096	1.01e-176	506.0	COG3328@1|root,COG3328@2|Bacteria,1G3YG@1117|Cyanobacteria	1117|Cyanobacteria	L	PFAM transposase mutator type	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_mut
k59_79523_1	158190.SpiGrapes_2789	1.04e-52	176.0	COG1172@1|root,COG1172@2|Bacteria,2J78F@203691|Spirochaetes	203691|Spirochaetes	G	PFAM Branched-chain amino acid transport system permease component	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
k59_79523_2	555779.Dthio_PD0736	1.08e-27	108.0	COG1943@1|root,COG1943@2|Bacteria,1MVUV@1224|Proteobacteria,43B13@68525|delta/epsilon subdivisions,2WS1C@28221|Deltaproteobacteria	1224|Proteobacteria	L	COG1943 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_192889_1	1121015.N789_07970	4.73e-29	118.0	COG2267@1|root,COG2267@2|Bacteria,1QTZP@1224|Proteobacteria,1RPB9@1236|Gammaproteobacteria,1XC31@135614|Xanthomonadales	135614|Xanthomonadales	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4
k59_170318_1	1121405.dsmv_0325	3.33e-21	95.1	COG4783@1|root,COG4783@2|Bacteria,1MVFV@1224|Proteobacteria,42MBR@68525|delta/epsilon subdivisions,2WJ0Z@28221|Deltaproteobacteria,2MHRK@213118|Desulfobacterales	28221|Deltaproteobacteria	S	PFAM peptidase	-	-	-	-	-	-	-	-	-	-	-	iAF987.Gmet_1238	Peptidase_M48,TPR_14,TPR_16,TPR_19
k59_71775_1	335543.Sfum_2527	7.99e-103	323.0	COG0013@1|root,COG0013@2|Bacteria,1MU9A@1224|Proteobacteria,42M70@68525|delta/epsilon subdivisions,2WJA8@28221|Deltaproteobacteria,2MQ85@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
k59_155396_1	1167006.UWK_00834	3.1e-15	75.9	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WJKZ@28221|Deltaproteobacteria,2MI48@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Bacterial regulatory protein, Fis family	-	-	-	ko:K07713	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
k59_155396_2	382464.ABSI01000011_gene2374	6.05e-161	473.0	COG0531@1|root,COG0531@2|Bacteria	2|Bacteria	E	amino acid	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
k59_3129_1	574087.Acear_0533	2.57e-14	73.9	COG4656@1|root,COG4656@2|Bacteria,1TPCC@1239|Firmicutes,24805@186801|Clostridia,3WAC6@53433|Halanaerobiales	186801|Clostridia	C	Part of a membrane complex involved in electron transport	rnfC	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K03615	-	-	-	-	ko00000	-	-	-	Complex1_51K,Fer4_10,RnfC_N,SLBB
k59_26057_1	1232410.KI421421_gene3541	3.23e-34	124.0	COG4103@1|root,COG4103@2|Bacteria,1N6YZ@1224|Proteobacteria,42WGY@68525|delta/epsilon subdivisions,2WS4W@28221|Deltaproteobacteria,43VDK@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Tellurite resistance protein TerB	-	-	-	-	-	-	-	-	-	-	-	-	TerB
k59_56825_1	56780.SYN_03223	1.16e-88	277.0	COG0459@1|root,COG0459@2|Bacteria,1MURR@1224|Proteobacteria,42M52@68525|delta/epsilon subdivisions,2WIRK@28221|Deltaproteobacteria,2MRAR@213462|Syntrophobacterales	28221|Deltaproteobacteria	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	-	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
k59_192890_1	232721.Ajs_2156	3.09e-91	280.0	COG3328@1|root,COG3328@2|Bacteria,1MU4P@1224|Proteobacteria,2VP71@28216|Betaproteobacteria	28216|Betaproteobacteria	L	PFAM transposase, mutator type	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_mut
k59_140217_1	335543.Sfum_0683	6.51e-76	237.0	COG1187@1|root,COG1187@2|Bacteria,1MUCE@1224|Proteobacteria,42NI7@68525|delta/epsilon subdivisions,2WNPX@28221|Deltaproteobacteria,2MQHH@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	Belongs to the pseudouridine synthase RsuA family	rluB	-	5.4.99.21,5.4.99.22	ko:K06178,ko:K06182	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
k59_140217_2	316067.Geob_3014	1.09e-57	187.0	COG1386@1|root,COG1386@2|Bacteria,1PUA6@1224|Proteobacteria,42SVD@68525|delta/epsilon subdivisions,2WPFX@28221|Deltaproteobacteria,43US2@69541|Desulfuromonadales	28221|Deltaproteobacteria	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves	scpB	-	-	ko:K06024	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpB
k59_26059_1	883078.HMPREF9695_03670	1.68e-13	76.6	COG3264@1|root,COG3264@2|Bacteria,1MWSA@1224|Proteobacteria,2TRKK@28211|Alphaproteobacteria,3JSMB@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	M	Mechanosensitive ion channel	MA20_40450	-	-	-	-	-	-	-	-	-	-	-	MS_channel
k59_132567_1	604354.TSIB_0771	7.15e-41	154.0	COG0446@1|root,COG0579@1|root,arCOG00754@2157|Archaea,arCOG05745@2157|Archaea,2Y8CD@28890|Euryarchaeota,242ZP@183968|Thermococci	183968|Thermococci	C	BFD-like [2Fe-2S] binding domain	-	-	1.1.5.3	ko:K00111	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	DAO,Fer2_BFD
k59_140218_1	927658.AJUM01000042_gene1581	7.33e-193	550.0	COG4974@1|root,COG4974@2|Bacteria,4NEK2@976|Bacteroidetes,2FMJC@200643|Bacteroidia,3XJ8A@558415|Marinilabiliaceae	976|Bacteroidetes	L	IS66 family element, transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS66,DDE_Tnp_IS66_C,LZ_Tnp_IS66
k59_140220_1	177439.DP0331	4.59e-66	210.0	COG2998@1|root,COG2998@2|Bacteria,1MVSF@1224|Proteobacteria,42NK5@68525|delta/epsilon subdivisions,2WJ49@28221|Deltaproteobacteria,2MJA7@213118|Desulfobacterales	28221|Deltaproteobacteria	H	PBP superfamily domain	-	-	-	ko:K05772	ko02010,map02010	M00186	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.2,3.A.1.6.4	-	-	PBP_like_2
k59_18504_1	1411123.JQNH01000001_gene972	7.22e-08	60.5	COG4166@1|root,COG4166@2|Bacteria,1P91R@1224|Proteobacteria,2TT6P@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	ABC-type oligopeptide transport system periplasmic component	oppA	-	-	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	SBP_bac_5
k59_41350_1	1121396.KB892924_gene599	1.11e-47	165.0	COG1045@1|root,COG1045@2|Bacteria,1MVFX@1224|Proteobacteria,42MND@68525|delta/epsilon subdivisions,2WJC3@28221|Deltaproteobacteria,2MIG5@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Bacterial transferase hexapeptide (six repeats)	cysE	-	2.3.1.30	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	M00021	R00586	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,SATase_N
k59_11362_1	443143.GM18_4036	4.39e-60	206.0	COG1360@1|root,COG2885@1|root,COG1360@2|Bacteria,COG2885@2|Bacteria,1QW22@1224|Proteobacteria,42TDV@68525|delta/epsilon subdivisions,2WP7K@28221|Deltaproteobacteria,43UHJ@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	OmpA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
k59_11362_2	1232410.KI421425_gene1551	3.48e-56	179.0	2B4XH@1|root,32REP@2|Bacteria,1PXEZ@1224|Proteobacteria,4305C@68525|delta/epsilon subdivisions,2WVH5@28221|Deltaproteobacteria,43UUP@69541|Desulfuromonadales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_33962_1	644968.DFW101_0070	5.51e-62	214.0	COG0577@1|root,COG2234@1|root,COG0577@2|Bacteria,COG2234@2|Bacteria,1MVYE@1224|Proteobacteria,42PKN@68525|delta/epsilon subdivisions,2WIWP@28221|Deltaproteobacteria,2M8ZJ@213115|Desulfovibrionales	28221|Deltaproteobacteria	V	FtsX-like permease family	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,PA,Peptidase_M28
k59_125187_1	1380391.JIAS01000012_gene4251	4.61e-05	53.1	COG0457@1|root,COG2114@1|root,COG3899@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG3899@2|Bacteria,1MUDT@1224|Proteobacteria,2TQVN@28211|Alphaproteobacteria,2JQNY@204441|Rhodospirillales	204441|Rhodospirillales	T	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Guanylate_cyc,SAM_1
k59_140225_1	926561.KB900617_gene1671	6.73e-07	55.1	COG1589@1|root,COG1589@2|Bacteria,1VKJ9@1239|Firmicutes,24WRA@186801|Clostridia,3WAX7@53433|Halanaerobiales	186801|Clostridia	M	Cell division protein FtsQ	-	-	-	ko:K03589	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036	-	-	-	FtsQ,POTRA_1
k59_102342_1	1121396.KB893002_gene3548	1.84e-28	109.0	COG2203@1|root,COG2203@2|Bacteria,1RM3C@1224|Proteobacteria,42T8V@68525|delta/epsilon subdivisions,2WP3I@28221|Deltaproteobacteria,2MKCM@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2
k59_18511_1	558152.IQ37_05485	1.16e-09	61.2	2EHX5@1|root,33BNR@2|Bacteria,4NXNQ@976|Bacteroidetes,1IIRM@117743|Flavobacteriia,3ZS18@59732|Chryseobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_109628_1	1506994.JNLQ01000002_gene2255	0.000291	42.0	2EVBX@1|root,33NSE@2|Bacteria,1VKHC@1239|Firmicutes,24WCF@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_155414_1	383372.Rcas_0546	9.95e-52	172.0	COG0411@1|root,COG0411@2|Bacteria,2G5VI@200795|Chloroflexi,376EN@32061|Chloroflexia	32061|Chloroflexia	E	PFAM ABC transporter related	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
k59_125189_1	1121405.dsmv_2225	3.09e-14	77.8	COG0760@1|root,COG0760@2|Bacteria,1MZDK@1224|Proteobacteria,42RVN@68525|delta/epsilon subdivisions,2WNJW@28221|Deltaproteobacteria,2MNB1@213118|Desulfobacterales	28221|Deltaproteobacteria	M	peptidylprolyl isomerase	-	-	5.2.1.8	ko:K03769	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N_3
k59_33969_1	156889.Mmc1_3409	1.13e-28	119.0	COG0642@1|root,COG0784@1|root,COG0834@1|root,COG2198@1|root,COG2202@1|root,COG0642@2|Bacteria,COG0784@2|Bacteria,COG0834@2|Bacteria,COG2198@2|Bacteria,COG2202@2|Bacteria,1NC9X@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K07678	ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111	M00475	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg,SBP_bac_3,dCache_1
k59_56849_1	690850.Desaf_1234	4.98e-147	432.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,42M51@68525|delta/epsilon subdivisions,2WIPP@28221|Deltaproteobacteria,2M915@213115|Desulfovibrionales	28221|Deltaproteobacteria	NU	PFAM Type II secretion system protein E	gspE	-	-	ko:K02454	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSE,T2SSE_N
k59_147337_1	335543.Sfum_0186	6.56e-106	321.0	COG0463@1|root,COG0463@2|Bacteria,1R547@1224|Proteobacteria,42PDC@68525|delta/epsilon subdivisions,2WKYW@28221|Deltaproteobacteria,2MR35@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	glycosyl transferase family 2	-	-	2.4.1.268	ko:K21349	-	-	-	-	ko00000,ko01000	-	GT81	-	Glycos_transf_2
k59_11378_1	1249975.JQLP01000003_gene262	1.34e-12	72.4	COG0642@1|root,COG0642@2|Bacteria,4NEW4@976|Bacteroidetes,1HZ62@117743|Flavobacteriia,2P79J@244698|Gillisia	976|Bacteroidetes	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
k59_140238_1	1121405.dsmv_1967	1.25e-109	335.0	COG1894@1|root,COG1894@2|Bacteria,1MV8F@1224|Proteobacteria,42N6N@68525|delta/epsilon subdivisions,2WJ1W@28221|Deltaproteobacteria,2MMTC@213118|Desulfobacterales	28221|Deltaproteobacteria	C	NADH-ubiquinone oxidoreductase-F iron-sulfur binding region	-	-	1.12.1.3,1.6.5.3	ko:K00124,ko:K00335,ko:K05587,ko:K18331	ko00190,ko00630,ko00680,ko01100,ko01120,ko01200,map00190,map00630,map00680,map01100,map01120,map01200	M00144	R00519,R11945	RC00061,RC02796	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx,Complex1_51K,Fer4,NADH_4Fe-4S,SLBB
k59_140238_2	1089553.Tph_c14870	3.33e-26	103.0	COG3383@1|root,COG3383@2|Bacteria,1V1Y2@1239|Firmicutes,24FSX@186801|Clostridia,42I7W@68295|Thermoanaerobacterales	186801|Clostridia	C	NADH-ubiquinone oxidoreductase-G iron-sulfur binding region	-	-	1.17.1.9,1.6.5.3	ko:K00123,ko:K00336	ko00190,ko00630,ko00680,ko01100,ko01120,ko01200,map00190,map00630,map00680,map01100,map01120,map01200	M00144	R00519,R11945	RC00061,RC02796	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,Fer4,Fer4_21,NADH-G_4Fe-4S_3
k59_102354_1	1313304.CALK_0546	2.26e-53	184.0	COG1282@1|root,COG1282@2|Bacteria	2|Bacteria	C	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane	pntB	-	1.6.1.2	ko:K00325	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	PNTB
k59_18520_1	43989.cce_0732	8.36e-24	103.0	COG4783@1|root,COG4783@2|Bacteria,1G3BT@1117|Cyanobacteria,3KHB6@43988|Cyanothece	1117|Cyanobacteria	S	Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
k59_132600_1	335543.Sfum_2084	5.52e-121	369.0	COG0495@1|root,COG0495@2|Bacteria,1MV47@1224|Proteobacteria,42MRQ@68525|delta/epsilon subdivisions,2WJ3E@28221|Deltaproteobacteria,2MQ60@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	TIGRFAM leucyl-tRNA synthetase	leuS	GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	iAF987.Gmet_2300	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
k59_48922_1	32042.PstZobell_01222	3e-53	178.0	COG4974@1|root,COG4974@2|Bacteria,1MVAN@1224|Proteobacteria,1RMSS@1236|Gammaproteobacteria,1Z160@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
k59_133197_1	573370.DMR_07030	4.95e-28	117.0	COG0210@1|root,COG0210@2|Bacteria,1MU0G@1224|Proteobacteria,42MKU@68525|delta/epsilon subdivisions,2WJR3@28221|Deltaproteobacteria,2M9BW@213115|Desulfovibrionales	28221|Deltaproteobacteria	L	PFAM UvrD REP helicase	pcrA	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
k59_87282_1	1322246.BN4_10036	1.59e-91	282.0	COG0747@1|root,COG0747@2|Bacteria,1MUZH@1224|Proteobacteria,42N74@68525|delta/epsilon subdivisions,2WKUN@28221|Deltaproteobacteria,2M7UW@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	extracellular solute-binding protein, family 5	-	-	-	ko:K02035,ko:K15584	ko02010,ko02024,map02010,map02024	M00239,M00440	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
k59_223689_1	492774.JQMB01000006_gene6535	3.07e-55	186.0	COG0665@1|root,COG0665@2|Bacteria,1MVGP@1224|Proteobacteria,2TRX9@28211|Alphaproteobacteria,4BBA4@82115|Rhizobiaceae	28211|Alphaproteobacteria	E	Oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
k59_140774_1	880072.Desac_2350	1.73e-45	157.0	COG0702@1|root,COG0702@2|Bacteria,1MW54@1224|Proteobacteria,42PP6@68525|delta/epsilon subdivisions,2WJN2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	GM	PFAM NAD-dependent epimerase dehydratase	-	-	1.6.5.3,1.6.99.3	ko:K00329,ko:K00356	ko00190,map00190	-	R11945	RC00061	ko00000,ko00001,ko01000	-	-	-	NAD_binding_10
k59_231858_1	1219035.NT2_27_00020	2.45e-11	67.0	COG3547@1|root,COG3547@2|Bacteria,1MUER@1224|Proteobacteria,2TSGZ@28211|Alphaproteobacteria,2K503@204457|Sphingomonadales	204457|Sphingomonadales	L	PFAM Transposase IS116 IS110 IS902 family, Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_12055_1	400668.Mmwyl1_0356	3.04e-36	143.0	COG3437@1|root,COG3437@2|Bacteria,1MUB8@1224|Proteobacteria,1RPH3@1236|Gammaproteobacteria,1XKSN@135619|Oceanospirillales	135619|Oceanospirillales	T	Response regulator receiver	-	-	-	ko:K07814	-	-	-	-	ko00000,ko02022	-	-	-	HD,HD_5,Response_reg
k59_72458_1	237368.SCABRO_01083	8e-226	637.0	COG0008@1|root,COG0008@2|Bacteria,2IYSE@203682|Planctomycetes	203682|Planctomycetes	J	tRNA synthetases class I (E and Q), anti-codon binding domain	glnS	-	6.1.1.18	ko:K01886	ko00970,ko01100,map00970,map01100	M00359,M00360	R03652	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1c,tRNA-synt_1c_C
k59_110319_1	933262.AXAM01000041_gene1901	8.75e-153	431.0	COG0247@1|root,COG0247@2|Bacteria,1R4ZK@1224|Proteobacteria,42NMT@68525|delta/epsilon subdivisions,2WIQV@28221|Deltaproteobacteria,2MJ6N@213118|Desulfobacterales	28221|Deltaproteobacteria	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_8
k59_110319_2	177437.HRM2_37640	5.41e-26	104.0	COG0247@1|root,COG0247@2|Bacteria,1N5Q2@1224|Proteobacteria,42P5D@68525|delta/epsilon subdivisions,2WJ9I@28221|Deltaproteobacteria,2MI9D@213118|Desulfobacterales	28221|Deltaproteobacteria	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_17,Fer4_8,Fer4_9
k59_209095_1	926692.AZYG01000085_gene856	3.73e-58	194.0	COG2801@1|root,COG2801@2|Bacteria,1TU21@1239|Firmicutes,249HN@186801|Clostridia,3WA8E@53433|Halanaerobiales	186801|Clostridia	L	Integrase catalytic region	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve
k59_3409_1	706587.Desti_4231	3.22e-21	91.7	COG0559@1|root,COG0559@2|Bacteria,1MY1E@1224|Proteobacteria,42RIK@68525|delta/epsilon subdivisions,2WNDV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Branched-chain amino acid transport system / permease component	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
k59_3409_2	1232410.KI421421_gene3446	2.01e-51	176.0	COG0683@1|root,COG0683@2|Bacteria,1MWNB@1224|Proteobacteria,42TEX@68525|delta/epsilon subdivisions,2WPG8@28221|Deltaproteobacteria,43T5H@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	Periplasmic binding protein domain	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
k59_72459_1	479433.Caci_4118	2.68e-20	96.3	COG2208@1|root,COG2208@2|Bacteria,2GKG3@201174|Actinobacteria	201174|Actinobacteria	KT	phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	ANTAR,GAF_2,PAS_3,SpoIIE
k59_57437_1	1500893.JQNB01000001_gene255	3.43e-06	56.2	COG1216@1|root,COG1216@2|Bacteria,1NM61@1224|Proteobacteria,1RRUD@1236|Gammaproteobacteria,1X2Z2@135614|Xanthomonadales	135614|Xanthomonadales	S	Glycosyl transferase	-	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glyco_tranf_2_3,Glyco_trans_2_3,Glycos_transf_2
k59_170983_1	1121405.dsmv_3218	3.26e-51	166.0	COG0799@1|root,COG0799@2|Bacteria,1MZEF@1224|Proteobacteria,42VN5@68525|delta/epsilon subdivisions,2WRGG@28221|Deltaproteobacteria,2MKMJ@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation	rsfS	-	-	ko:K09710	-	-	-	-	ko00000,ko03009	-	-	-	RsfS
k59_64497_1	44251.PDUR_19865	9.48e-40	137.0	COG2001@1|root,COG2001@2|Bacteria,1V3JD@1239|Firmicutes,4HH23@91061|Bacilli,26WUX@186822|Paenibacillaceae	91061|Bacilli	K	Belongs to the MraZ family	mraZ	GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141	-	ko:K03925	-	-	-	-	ko00000	-	-	-	MraZ
k59_87292_1	335543.Sfum_0385	1.72e-71	224.0	COG0559@1|root,COG0559@2|Bacteria,1MU25@1224|Proteobacteria,43AMG@68525|delta/epsilon subdivisions,2X61G@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Branched-chain amino acid transport system / permease component	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
k59_117383_1	96561.Dole_0342	2.05e-61	196.0	COG0735@1|root,COG1918@1|root,COG0735@2|Bacteria,COG1918@2|Bacteria,1RDWJ@1224|Proteobacteria,42P61@68525|delta/epsilon subdivisions,2X5PQ@28221|Deltaproteobacteria,2MJ7H@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Belongs to the Fur family	-	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR,FeoA
k59_95129_2	1167006.UWK_02077	7.98e-49	161.0	COG0264@1|root,COG0264@2|Bacteria,1MUS2@1224|Proteobacteria,42NNS@68525|delta/epsilon subdivisions,2WMS3@28221|Deltaproteobacteria,2MI7H@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
k59_231875_2	309799.DICTH_1701	7.06e-21	92.4	COG0664@1|root,COG0664@2|Bacteria	2|Bacteria	T	cyclic nucleotide binding	-	-	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
k59_34606_1	1121405.dsmv_3079	1.69e-133	381.0	COG0500@1|root,COG2226@2|Bacteria,1QU24@1224|Proteobacteria,43BNY@68525|delta/epsilon subdivisions,2X70A@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Mycolic acid cyclopropane synthetase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
k59_72473_1	1125863.JAFN01000001_gene769	4.01e-61	210.0	COG0542@1|root,COG0542@2|Bacteria,1MURH@1224|Proteobacteria,42M9S@68525|delta/epsilon subdivisions,2WJSZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
k59_193215_1	1140002.I570_02324	2.72e-22	99.0	COG3344@1|root,COG3344@2|Bacteria,1TP9A@1239|Firmicutes,4H9NW@91061|Bacilli	91061|Bacilli	L	reverse transcriptase	-	-	-	-	-	-	-	-	-	-	-	-	Intron_maturas2,RVT_1
k59_80083_3	1073999.BN137_1161	4.82e-15	77.8	2C0FK@1|root,32R6X@2|Bacteria,1RIG4@1224|Proteobacteria,1S7T1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	stfP	-	-	-	-	-	-	-	-	-	-	-	-
k59_69291_1	999413.HMPREF1094_02407	1.02e-45	159.0	COG0444@1|root,COG0444@2|Bacteria,1TP6E@1239|Firmicutes,3VNWI@526524|Erysipelotrichia	526524|Erysipelotrichia	P	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,oligo_HPY
k59_160405_1	706587.Desti_2340	4.12e-97	301.0	COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,42MHP@68525|delta/epsilon subdivisions,2WIQG@28221|Deltaproteobacteria,2MR4C@213462|Syntrophobacterales	28221|Deltaproteobacteria	F	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	acsA	-	6.2.1.1,6.2.1.17	ko:K01895,ko:K01908	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
k59_16157_1	350688.Clos_1104	1.38e-43	147.0	COG1763@1|root,COG1763@2|Bacteria,1V3U5@1239|Firmicutes,25CJD@186801|Clostridia,36WX4@31979|Clostridiaceae	186801|Clostridia	H	PFAM molybdopterin-guanine dinucleotide biosynthesis MobB region	mobB	-	-	ko:K03753	-	-	-	-	ko00000	-	-	-	MobB
k59_122391_1	1469245.JFBG01000019_gene1116	3.44e-13	74.3	COG0621@1|root,COG0621@2|Bacteria,1MURS@1224|Proteobacteria,1RMD8@1236|Gammaproteobacteria,1WWN1@135613|Chromatiales	135613|Chromatiales	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
k59_39023_1	589865.DaAHT2_1174	5.97e-189	540.0	COG0541@1|root,COG0541@2|Bacteria,1MVIA@1224|Proteobacteria,42M94@68525|delta/epsilon subdivisions,2WINB@28221|Deltaproteobacteria,2MHWE@213118|Desulfobacterales	28221|Deltaproteobacteria	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components	ffh	-	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
k59_39023_2	335543.Sfum_3039	2.61e-32	114.0	COG0228@1|root,COG0228@2|Bacteria,1MZCT@1224|Proteobacteria,42V30@68525|delta/epsilon subdivisions,2WRH7@28221|Deltaproteobacteria,2MQN6@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	Ribosomal protein S16	rpsP	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02959	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S16
k59_99622_1	1120956.JHZK01000023_gene1104	3.32e-23	102.0	COG1752@1|root,COG1752@2|Bacteria,1NT1Q@1224|Proteobacteria,2TRM3@28211|Alphaproteobacteria,1JQ5F@119043|Rhodobiaceae	28211|Alphaproteobacteria	S	Patatin-like phospholipase	-	-	-	-	-	-	-	-	-	-	-	-	Patatin
k59_69296_1	335543.Sfum_4075	5.58e-168	491.0	COG4231@1|root,COG4231@2|Bacteria,1MUKS@1224|Proteobacteria,42N44@68525|delta/epsilon subdivisions,2WIX6@28221|Deltaproteobacteria,2MR22@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates	iorA	-	1.2.7.8	ko:K00179	-	-	-	-	br01601,ko00000,ko01000	-	-	-	Fer4,POR_N,TPP_enzyme_C
k59_130014_1	138119.DSY0313	6.62e-05	45.4	COG0247@1|root,COG0247@2|Bacteria,1TSC1@1239|Firmicutes,24B10@186801|Clostridia,260AF@186807|Peptococcaceae	186801|Clostridia	C	4Fe-4S dicluster domain	hmeD	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_8
k59_130014_2	1121405.dsmv_2240	9.34e-66	202.0	arCOG10385@1|root,32SEM@2|Bacteria,1N1IG@1224|Proteobacteria,42TMW@68525|delta/epsilon subdivisions,2WQBW@28221|Deltaproteobacteria,2MK19@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	dsrJ	-	-	-	-	-	-	-	-	-	-	-	-
k59_8639_1	1255043.TVNIR_1343	3.57e-09	56.2	COG0517@1|root,COG0517@2|Bacteria,1N0H3@1224|Proteobacteria,1T5A0@1236|Gammaproteobacteria,1WZ3D@135613|Chromatiales	135613|Chromatiales	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
k59_167753_1	909663.KI867150_gene214	6.55e-34	135.0	COG0457@1|root,COG1807@1|root,COG0457@2|Bacteria,COG1807@2|Bacteria,1NNJ6@1224|Proteobacteria,42PBD@68525|delta/epsilon subdivisions,2WKWJ@28221|Deltaproteobacteria,2MRCI@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	PFAM Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2,TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8
k59_122401_1	335543.Sfum_1225	2.67e-118	374.0	COG0587@1|root,COG0587@2|Bacteria,1MUIF@1224|Proteobacteria,42MGP@68525|delta/epsilon subdivisions,2WIZ2@28221|Deltaproteobacteria,2MQUW@213462|Syntrophobacterales	28221|Deltaproteobacteria	L	DNA polymerase III alpha subunit	dnaE	-	2.7.7.7	ko:K02337,ko:K14162	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
k59_69722_1	552811.Dehly_1535	2.37e-119	349.0	COG3547@1|root,COG3547@2|Bacteria,2G8GZ@200795|Chloroflexi	200795|Chloroflexi	L	transposase IS116 IS110 IS902 family protein	-	-	-	ko:K07486	-	-	-	-	ko00000	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_84828_1	1121405.dsmv_2871	2.04e-38	140.0	COG0699@1|root,COG0699@2|Bacteria,1MV59@1224|Proteobacteria,42MBS@68525|delta/epsilon subdivisions,2WJVE@28221|Deltaproteobacteria,2MJ8T@213118|Desulfobacterales	28221|Deltaproteobacteria	S	PFAM Dynamin family	-	-	-	-	-	-	-	-	-	-	-	-	Dynamin_N
k59_84828_2	909663.KI867150_gene523	3.23e-07	50.4	COG2050@1|root,COG2050@2|Bacteria,1N5HF@1224|Proteobacteria,42RQZ@68525|delta/epsilon subdivisions,2WNIY@28221|Deltaproteobacteria,2MRSF@213462|Syntrophobacterales	28221|Deltaproteobacteria	Q	Thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
k59_213781_1	237368.SCABRO_01325	5.12e-35	133.0	COG2206@1|root,COG2206@2|Bacteria,2J0TK@203682|Planctomycetes	203682|Planctomycetes	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	HD_5
k59_100094_1	1463909.KL585972_gene3561	1.77e-15	85.9	COG3934@1|root,COG3934@2|Bacteria,2GNN6@201174|Actinobacteria	201174|Actinobacteria	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	-	-	-	-	-	-	-	-	-	-	-	-	Cellulase
k59_77493_1	439235.Dalk_0888	3.99e-170	490.0	COG0297@1|root,COG0297@2|Bacteria,1MUGM@1224|Proteobacteria,42MT8@68525|delta/epsilon subdivisions,2WITI@28221|Deltaproteobacteria,2MIZ1@213118|Desulfobacterales	28221|Deltaproteobacteria	G	PFAM Starch synthase catalytic	-	-	2.4.1.21,3.2.1.1	ko:K00703,ko:K01176	ko00500,ko01100,ko01110,ko02026,ko04973,map00500,map01100,map01110,map02026,map04973	M00565	R02108,R02112,R02421,R11262	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GH13,GT5	-	Glyco_trans_1_4,Glyco_transf_5,Glycos_transf_1
k59_47072_1	63737.Npun_R1017	1.89e-126	376.0	COG1449@1|root,COG1449@2|Bacteria,1G0B0@1117|Cyanobacteria,1HJIJ@1161|Nostocales	1117|Cyanobacteria	G	Belongs to the glycosyl hydrolase 57 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_57
k59_92475_1	338963.Pcar_1514	1.42e-54	184.0	COG3635@1|root,COG3635@2|Bacteria,1R4TM@1224|Proteobacteria,42NCT@68525|delta/epsilon subdivisions,2WKEG@28221|Deltaproteobacteria,43SUK@69541|Desulfuromonadales	28221|Deltaproteobacteria	G	Proposed homoserine kinase	apgM	-	5.4.2.12	ko:K15635	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,PhosphMutase
k59_31817_1	991905.SL003B_0692	4.34e-45	148.0	COG2337@1|root,COG2337@2|Bacteria,1N0JV@1224|Proteobacteria,2UFG0@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	Toxic component of a toxin-antitoxin (TA) module	-	-	-	ko:K07171	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PemK_toxin
k59_31817_2	489825.LYNGBM3L_26210	9.33e-28	102.0	COG2336@1|root,COG2336@2|Bacteria,1G88T@1117|Cyanobacteria,1HC8R@1150|Oscillatoriales	1117|Cyanobacteria	T	SpoVT / AbrB like domain	-	-	-	ko:K07172	-	-	-	-	ko00000,ko02048	-	-	-	MazE_antitoxin
k59_9121_2	1121396.KB893053_gene2346	3.03e-18	89.4	COG0544@1|root,COG0544@2|Bacteria,1MUJP@1224|Proteobacteria,42MBB@68525|delta/epsilon subdivisions,2WIU1@28221|Deltaproteobacteria,2MHZ5@213118|Desulfobacterales	28221|Deltaproteobacteria	D	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C,Trigger_N
k59_77504_1	335543.Sfum_3243	2.02e-49	177.0	COG2202@1|root,COG4585@1|root,COG2202@2|Bacteria,COG4585@2|Bacteria,1MWPN@1224|Proteobacteria,42SJA@68525|delta/epsilon subdivisions	1224|Proteobacteria	T	histidine kinase, dimerisation and phosphoacceptor region	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3,PAS,PAS_4,PAS_9
k59_39480_1	1304885.AUEY01000015_gene3004	2.31e-19	87.0	COG2820@1|root,COG2820@2|Bacteria,1QW1B@1224|Proteobacteria,42R3X@68525|delta/epsilon subdivisions,2WP50@28221|Deltaproteobacteria,2MKA8@213118|Desulfobacterales	28221|Deltaproteobacteria	F	PFAM purine or other phosphorylase family 1	-	-	-	-	-	-	-	-	-	-	-	-	PNP_UDP_1
k59_31828_1	1095767.CAHD01000057_gene398	1.82e-09	58.2	COG0359@1|root,COG0359@2|Bacteria,2IKX7@201174|Actinobacteria,4F19C@85016|Cellulomonadaceae	201174|Actinobacteria	J	Binds to the 23S rRNA	rplI	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02939	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L9_C,Ribosomal_L9_N
k59_31828_2	56780.SYN_00640	4.54e-22	95.5	COG0305@1|root,COG0305@2|Bacteria,1MUG9@1224|Proteobacteria,42M7X@68525|delta/epsilon subdivisions,2WJCA@28221|Deltaproteobacteria,2MQ50@213462|Syntrophobacterales	28221|Deltaproteobacteria	L	it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins	dnaB	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
k59_9124_1	1123376.AUIU01000018_gene46	4.53e-89	288.0	COG0188@1|root,COG0188@2|Bacteria,3J0EH@40117|Nitrospirae	40117|Nitrospirae	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
k59_47087_1	96561.Dole_3054	9.6e-35	121.0	COG0762@1|root,COG0762@2|Bacteria,1QDB9@1224|Proteobacteria,42VCU@68525|delta/epsilon subdivisions,2WRHX@28221|Deltaproteobacteria,2MKPA@213118|Desulfobacterales	28221|Deltaproteobacteria	S	YGGT family	-	-	-	ko:K02221	-	-	-	-	ko00000,ko02044	-	-	-	YGGT
k59_191035_1	1047013.AQSP01000095_gene2313	1.04e-28	115.0	COG3804@1|root,COG3804@2|Bacteria,2NP85@2323|unclassified Bacteria	2|Bacteria	S	dihydrodipicolinate reductase	ord	GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0047530,GO:0055114,GO:0071704,GO:1901564,GO:1901605	1.4.1.12,1.4.1.16,1.4.1.26	ko:K03340,ko:K21672	ko00300,ko00310,ko00330,ko00472,ko01100,ko01110,ko01230,map00300,map00310,map00330,map00472,map01100,map01110,map01230	M00526	R02755,R02825,R04200,R04201,R04687,R04688	RC00006,RC00249,RC00790	ko00000,ko00001,ko00002,ko01000	-	-	-	DapB_N
k59_39489_1	1121403.AUCV01000017_gene4456	1.46e-62	205.0	COG0426@1|root,COG0426@2|Bacteria,1NDXY@1224|Proteobacteria,42N11@68525|delta/epsilon subdivisions,2WJ8Z@28221|Deltaproteobacteria,2MI4R@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM Metallo-beta-lactamase superfamily	roo	-	1.6.3.4	ko:K22405	-	-	-	-	ko00000,ko01000	-	-	-	Flavodoxin_1,Lactamase_B
k59_54620_1	999630.TUZN_0326	1.13e-17	83.6	COG0084@1|root,arCOG00891@2157|Archaea,2XQ78@28889|Crenarchaeota	28889|Crenarchaeota	L	PFAM TatD-related deoxyribonuclease	-	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
k59_213807_1	439235.Dalk_1794	1.03e-14	74.3	COG0763@1|root,COG0763@2|Bacteria,1MVBI@1224|Proteobacteria,42P35@68525|delta/epsilon subdivisions,2WJFA@28221|Deltaproteobacteria,2MIFD@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxB	GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	2.4.1.182	ko:K00748	ko00540,ko01100,map00540,map01100	M00060	R04606	RC00005,RC00059	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT19	-	LpxB
k59_213807_2	690850.Desaf_2761	4.36e-20	88.2	COG1043@1|root,COG1043@2|Bacteria,1MUHQ@1224|Proteobacteria,42NPG@68525|delta/epsilon subdivisions,2WJVP@28221|Deltaproteobacteria,2M9DB@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxA	-	2.3.1.129	ko:K00677	ko00540,ko01100,ko01503,map00540,map01100,map01503	M00060	R04567	RC00039,RC00055	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Acetyltransf_11,Hexapep
k59_62317_1	1120959.ATXF01000005_gene1504	0.000161	44.7	COG1716@1|root,COG1716@2|Bacteria,2GKA7@201174|Actinobacteria,4FNUE@85023|Microbacteriaceae	201174|Actinobacteria	T	Forkhead associated domain	fhaB	GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006950,GO:0006979,GO:0008150,GO:0009987,GO:0016020,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044464,GO:0050896,GO:0051301,GO:0051704,GO:0071944	-	-	-	-	-	-	-	-	-	-	FHA,Yop-YscD_cpl
k59_1457_1	1168067.JAGP01000001_gene2068	1.88e-12	65.1	COG1758@1|root,COG1758@2|Bacteria,1N6TX@1224|Proteobacteria,1SCSR@1236|Gammaproteobacteria,4618M@72273|Thiotrichales	72273|Thiotrichales	K	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits	rpoZ	-	2.7.7.6	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb6
k59_1457_3	883158.HMPREF9140_00929	7.05e-07	50.1	COG0484@1|root,COG0484@2|Bacteria,4NF41@976|Bacteroidetes,2FPHH@200643|Bacteroidia	976|Bacteroidetes	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
k59_39506_1	526222.Desal_2697	7.34e-55	186.0	COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,42M9N@68525|delta/epsilon subdivisions,2WIZR@28221|Deltaproteobacteria,2M9FR@213115|Desulfovibrionales	28221|Deltaproteobacteria	G	PFAM TRAP C4-dicarboxylate transport system permease DctM subunit	-	-	-	-	-	-	-	-	-	-	-	-	DctM
k59_236621_1	1256908.HMPREF0373_02463	1.01e-36	134.0	COG4177@1|root,COG4177@2|Bacteria,1TPMZ@1239|Firmicutes,248WH@186801|Clostridia,25WAG@186806|Eubacteriaceae	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 10.00	-	-	-	ko:K01998,ko:K11961	ko02010,ko02024,map02010,map02024	M00237,M00323	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4,3.A.1.4.4,3.A.1.4.5	-	-	BPD_transp_2
k59_39511_1	179408.Osc7112_5102	4.16e-36	139.0	COG1007@1|root,COG1007@2|Bacteria,1G1FM@1117|Cyanobacteria,1H7W8@1150|Oscillatoriales	1117|Cyanobacteria	C	electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and or the photosynthetic chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient. Cyanobacterial NDH-1 also plays a role in inorganic carbon- concentration	ndhB	-	1.6.5.3	ko:K05573	ko00190,ko01100,map00190,map01100	M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	-	-	iJN678.ndhB	Proton_antipo_M
k59_153332_1	1121918.ARWE01000001_gene2220	2.89e-05	49.3	COG0745@1|root,COG0745@2|Bacteria,1QZ5N@1224|Proteobacteria,4307W@68525|delta/epsilon subdivisions,2X7RC@28221|Deltaproteobacteria,43UV3@69541|Desulfuromonadales	28221|Deltaproteobacteria	KT	PilZ domain	-	-	-	-	-	-	-	-	-	-	-	-	PilZ,Response_reg
k59_198694_1	933262.AXAM01000008_gene1929	4.92e-29	115.0	2EZEE@1|root,33SJJ@2|Bacteria,1NT85@1224|Proteobacteria,42ZA7@68525|delta/epsilon subdivisions,2WURF@28221|Deltaproteobacteria,2MMZQ@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_115140_1	177437.HRM2_24960	6.41e-33	124.0	COG0321@1|root,COG0321@2|Bacteria,1MU6A@1224|Proteobacteria,42RIC@68525|delta/epsilon subdivisions,2WNRX@28221|Deltaproteobacteria,2MJS6@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate	lipB	GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564	2.3.1.181	ko:K03801	ko00785,ko01100,map00785,map01100	-	R07766,R07769	RC00039,RC00992,RC02867	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB
k59_221539_2	1123508.JH636442_gene4492	6.62e-27	105.0	COG1611@1|root,COG1611@2|Bacteria	2|Bacteria	S	cytokinin biosynthetic process	CP_0264	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox,TIR_2
k59_145660_2	335543.Sfum_3398	4.29e-136	392.0	COG4177@1|root,COG4177@2|Bacteria,1MU52@1224|Proteobacteria,42RI3@68525|delta/epsilon subdivisions,2WNVC@28221|Deltaproteobacteria,2MRT0@213462|Syntrophobacterales	28221|Deltaproteobacteria	U	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
k59_77519_1	926569.ANT_00920	1.96e-36	138.0	COG2199@1|root,COG2199@2|Bacteria	2|Bacteria	T	diguanylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GGDEF,PAS_4,PAS_8,PAS_9
k59_9142_1	1410626.JHXB01000001_gene2299	2.41e-52	181.0	COG0621@1|root,COG0621@2|Bacteria,1TP2W@1239|Firmicutes,2487D@186801|Clostridia,27ISW@186928|unclassified Lachnospiraceae	186801|Clostridia	J	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12	rimO	-	2.8.4.4	ko:K14441	-	-	R10652	RC00003,RC03217	ko00000,ko01000,ko03009	-	-	-	Radical_SAM,TRAM,UPF0004
k59_115142_1	933262.AXAM01000013_gene1328	1.09e-69	221.0	COG0016@1|root,COG0016@2|Bacteria,1MVD7@1224|Proteobacteria,42MB0@68525|delta/epsilon subdivisions,2WJ42@28221|Deltaproteobacteria,2MI3B@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily	pheS	GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iAF987.Gmet_1415	Phe_tRNA-synt_N,tRNA-synt_2d
k59_168233_1	398767.Glov_1689	1.12e-55	183.0	COG0489@1|root,COG0489@2|Bacteria,1MU7R@1224|Proteobacteria,42NR0@68525|delta/epsilon subdivisions,2WIPG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	-	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	Nitro_FeMo-Co,ParA
k59_138133_2	983548.Krodi_0264	2.56e-80	249.0	COG3367@1|root,COG3367@2|Bacteria,4NGXN@976|Bacteroidetes,1I06G@117743|Flavobacteriia,37FQI@326319|Dokdonia	976|Bacteroidetes	S	Domain of unknown function (DUF1611_N) Rossmann-like domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF1611,DUF1611_N
k59_153342_1	1265505.ATUG01000001_gene4139	1.43e-83	261.0	COG5598@1|root,COG5598@2|Bacteria,1MWJN@1224|Proteobacteria,42Q8R@68525|delta/epsilon subdivisions,2WMDK@28221|Deltaproteobacteria,2MJEG@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Trimethylamine methyltransferase	-	-	2.1.1.250	ko:K14083	ko00680,ko01120,ko01200,map00680,map01120,map01200	M00563	R09124,R10016	RC00035,RC00732,RC01144,RC02984	ko00000,ko00001,ko00002,ko01000	-	-	-	MTTB
k59_31852_1	1173024.KI912151_gene1625	6.61e-165	487.0	COG0058@1|root,COG0058@2|Bacteria,1FZUX@1117|Cyanobacteria,1JKQ6@1189|Stigonemataceae	1117|Cyanobacteria	G	Carbohydrate phosphorylase	glgP	GO:0000272,GO:0003674,GO:0003824,GO:0004645,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0005976,GO:0005977,GO:0005980,GO:0006073,GO:0006091,GO:0006112,GO:0008144,GO:0008150,GO:0008152,GO:0008184,GO:0009056,GO:0009057,GO:0009251,GO:0009987,GO:0015980,GO:0016052,GO:0016740,GO:0016757,GO:0016758,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044247,GO:0044248,GO:0044260,GO:0044262,GO:0044264,GO:0044275,GO:0044424,GO:0044464,GO:0048037,GO:0050662,GO:0055114,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901575	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	Phosphorylase
k59_130582_1	1322246.BN4_10655	9.2e-06	47.8	COG3075@1|root,COG3075@2|Bacteria,1MU3K@1224|Proteobacteria,42Q09@68525|delta/epsilon subdivisions,2WKE0@28221|Deltaproteobacteria,2M7WY@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	Glycerol-3-phosphate dehydrogenase, anaerobic, B subunit	glpB	-	1.1.5.3	ko:K00112	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	FAD_binding_2
k59_130582_2	177437.HRM2_03220	6e-43	155.0	COG0578@1|root,COG0578@2|Bacteria,1MUMY@1224|Proteobacteria,42M8D@68525|delta/epsilon subdivisions,2WJ6E@28221|Deltaproteobacteria,2MIEK@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family	glpA	-	1.1.5.3	ko:K00111	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	DAO,DAO_C,Fer2_BFD
k59_54632_1	1232437.KL662073_gene1725	1.63e-113	346.0	COG4666@1|root,COG4666@2|Bacteria,1MUNB@1224|Proteobacteria,42MEV@68525|delta/epsilon subdivisions,2WK2S@28221|Deltaproteobacteria,2MIMQ@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF3394)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3394,DctM
k59_145669_1	1122169.AREN01000018_gene2202	4.24e-107	342.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,1JCKK@118969|Legionellales	118969|Legionellales	U	AcrB/AcrD/AcrF family	lmxF_2	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_191081_1	997296.PB1_09847	7.91e-26	99.8	COG0509@1|root,COG0509@2|Bacteria,1V6WV@1239|Firmicutes,4HIMA@91061|Bacilli,1ZGG0@1386|Bacillus	91061|Bacilli	E	Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate	gcvH	GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	-	GCV_H
k59_202065_1	756272.Plabr_3333	3.62e-36	128.0	COG0745@1|root,COG0745@2|Bacteria,2IZAH@203682|Planctomycetes	203682|Planctomycetes	T	response regulator receiver	-	-	2.7.7.65	ko:K02488	ko02020,ko04112,map02020,map04112	M00511	R08057	-	ko00000,ko00001,ko00002,ko01000,ko02022	-	-	-	Response_reg
k59_187174_1	933262.AXAM01000036_gene2186	8.99e-46	157.0	COG1381@1|root,COG1381@2|Bacteria,1RIBW@1224|Proteobacteria,42PUE@68525|delta/epsilon subdivisions,2WK4W@28221|Deltaproteobacteria,2MJFE@213118|Desulfobacterales	28221|Deltaproteobacteria	L	Involved in DNA repair and RecF pathway recombination	recO	-	-	ko:K03584	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecO_C,RecO_N
k59_95810_1	1125863.JAFN01000001_gene151	1.24e-141	410.0	COG1744@1|root,COG1744@2|Bacteria,1MWTM@1224|Proteobacteria,42NPH@68525|delta/epsilon subdivisions,2WIXM@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM Basic membrane	-	-	-	ko:K02058	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	Bmp
k59_148263_1	1379698.RBG1_1C00001G1511	2.79e-149	439.0	COG0312@1|root,COG0312@2|Bacteria,2NPIS@2323|unclassified Bacteria	2|Bacteria	S	Putative modulator of DNA gyrase	tldD2	-	-	ko:K03568	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
k59_187179_1	935948.KE386495_gene2020	2.13e-57	197.0	COG0449@1|root,COG0449@2|Bacteria,1TPGU@1239|Firmicutes,248F8@186801|Clostridia,42EKN@68295|Thermoanaerobacterales	186801|Clostridia	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	GATase_6,SIS
k59_65105_2	1121403.AUCV01000060_gene3708	3.38e-16	77.4	COG0436@1|root,COG0436@2|Bacteria,1MWS8@1224|Proteobacteria,42MEF@68525|delta/epsilon subdivisions,2WJ4D@28221|Deltaproteobacteria,2MI6F@213118|Desulfobacterales	28221|Deltaproteobacteria	E	PFAM aminotransferase class I and II	yfdZ	-	2.6.1.83	ko:K10206,ko:K14261	ko00300,ko01100,ko01110,ko01130,ko01230,map00300,map01100,map01110,map01130,map01230	M00527	R07613	RC00006,RC01847	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
k59_88004_1	234267.Acid_1198	1.2e-51	181.0	COG1321@1|root,COG1321@2|Bacteria	2|Bacteria	K	iron dependent repressor	nagC	-	-	ko:K02003,ko:K02565,ko:K15545	-	M00258	-	-	ko00000,ko00002,ko02000,ko03000	3.A.1	-	-	HTH_IclR,MarR,ROK
k59_49954_1	1265505.ATUG01000002_gene1612	1.9e-64	214.0	COG2204@1|root,COG4191@1|root,COG2204@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42PZ5@68525|delta/epsilon subdivisions,2WKB1@28221|Deltaproteobacteria,2MIJB@213118|Desulfobacterales	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
k59_193822_1	1121405.dsmv_1660	1.74e-169	479.0	COG2010@1|root,COG2993@1|root,COG2010@2|Bacteria,COG2993@2|Bacteria,1MXEY@1224|Proteobacteria,42NZG@68525|delta/epsilon subdivisions,2WNX9@28221|Deltaproteobacteria,2MKZC@213118|Desulfobacterales	28221|Deltaproteobacteria	C	cytochrome C oxidase mono-heme subunit FixO	-	-	-	ko:K00405	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	Cytochrome_CBB3,FixO
k59_178669_1	1121403.AUCV01000056_gene3021	1.25e-116	344.0	COG0330@1|root,COG0330@2|Bacteria,1MUM2@1224|Proteobacteria,42NUT@68525|delta/epsilon subdivisions,2WKQX@28221|Deltaproteobacteria,2MI5I@213118|Desulfobacterales	28221|Deltaproteobacteria	O	HflC and HflK could encode or regulate a protease	hflK	-	-	ko:K04088	-	M00742	-	-	ko00000,ko00002,ko01000	-	-	-	Band_7
k59_111020_1	177437.HRM2_24470	2.02e-88	275.0	COG2357@1|root,COG2357@2|Bacteria,1RCHE@1224|Proteobacteria,42PPK@68525|delta/epsilon subdivisions,2WJBS@28221|Deltaproteobacteria,2MHSG@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Region found in RelA / SpoT proteins	-	-	-	-	-	-	-	-	-	-	-	-	RelA_SpoT
k59_88008_1	335543.Sfum_1179	6.92e-92	285.0	COG1148@1|root,COG1148@2|Bacteria,1PZ04@1224|Proteobacteria,42PT3@68525|delta/epsilon subdivisions,2WMJU@28221|Deltaproteobacteria,2MR5J@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	FAD dependent oxidoreductase	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Pyr_redox_2
k59_209765_1	335543.Sfum_1609	4.19e-99	303.0	COG1530@1|root,COG1530@2|Bacteria,1MV65@1224|Proteobacteria,42M5E@68525|delta/epsilon subdivisions,2WIV6@28221|Deltaproteobacteria,2MQAN@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	TIGRFAM ribonuclease, Rne Rng family	cafA	-	3.1.26.12	ko:K08300,ko:K08301	ko03018,map03018	M00394	-	-	ko00000,ko00001,ko00002,ko01000,ko03009,ko03019	-	-	-	RNase_E_G,S1
k59_27033_1	335543.Sfum_3972	5.05e-82	263.0	COG4805@1|root,COG4805@2|Bacteria,1R5EP@1224|Proteobacteria,42ZIG@68525|delta/epsilon subdivisions,2WUZE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
k59_126408_1	1322246.BN4_12721	1.1e-85	263.0	COG4603@1|root,COG4603@2|Bacteria,1MX6V@1224|Proteobacteria,42MWE@68525|delta/epsilon subdivisions,2WKIZ@28221|Deltaproteobacteria,2MGK9@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
k59_58084_1	1307759.JOMJ01000003_gene1399	1.42e-12	68.9	COG1656@1|root,COG1656@2|Bacteria,1R442@1224|Proteobacteria,42RIS@68525|delta/epsilon subdivisions,2WMWC@28221|Deltaproteobacteria,2MB5G@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Mut7-C RNAse domain	-	-	-	ko:K09122	-	-	-	-	ko00000	-	-	-	Mut7-C,Ub-Mut7C
k59_58084_2	56780.SYN_02931	6.53e-62	196.0	COG0521@1|root,COG0521@2|Bacteria,1R9W2@1224|Proteobacteria,42PGH@68525|delta/epsilon subdivisions,2WPJ6@28221|Deltaproteobacteria,2MQG2@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	molybdenum cofactor	moaB	-	2.7.7.75	ko:K03638,ko:K03831	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09726	RC00002	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth
k59_141507_1	439235.Dalk_2485	7.77e-72	221.0	COG1100@1|root,COG1100@2|Bacteria,1R6NS@1224|Proteobacteria,42NIX@68525|delta/epsilon subdivisions,2WJ44@28221|Deltaproteobacteria,2MI9K@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Gtr1/RagA G protein conserved region	mglA	GO:0008150,GO:0032879,GO:0032880,GO:0050789,GO:0065007	-	ko:K06883	-	-	-	-	ko00000	-	-	-	Arf,Ras
k59_224318_1	180332.JTGN01000002_gene5723	7.15e-86	261.0	COG1402@1|root,COG1402@2|Bacteria,1V0N8@1239|Firmicutes,24BWG@186801|Clostridia	186801|Clostridia	S	Creatinine amidohydrolase	-	-	3.5.2.10	ko:K01470,ko:K22232	ko00330,ko00562,map00330,map00562	-	R01884,R11771	RC00615	ko00000,ko00001,ko01000	-	-	-	Creatininase
k59_202073_1	880072.Desac_1429	1.48e-113	329.0	COG0522@1|root,COG0522@2|Bacteria,1MW0U@1224|Proteobacteria,42M5X@68525|delta/epsilon subdivisions,2WJGN@28221|Deltaproteobacteria,2MRHQ@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
k59_202073_2	335543.Sfum_1580	4.43e-73	221.0	COG0100@1|root,COG0100@2|Bacteria,1RD0A@1224|Proteobacteria,42R43@68525|delta/epsilon subdivisions,2WPH1@28221|Deltaproteobacteria,2MQGH@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome	rpsK	GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
k59_202073_3	335543.Sfum_1579	2.94e-68	208.0	COG0099@1|root,COG0099@2|Bacteria,1RD1G@1224|Proteobacteria,42RE3@68525|delta/epsilon subdivisions,2WPD5@28221|Deltaproteobacteria,2MRU2@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	rpsM	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
k59_224324_1	1304885.AUEY01000021_gene3472	8.04e-09	57.4	COG3437@1|root,COG3437@2|Bacteria,1MUB8@1224|Proteobacteria,42M4Y@68525|delta/epsilon subdivisions,2WKKD@28221|Deltaproteobacteria,2MIK0@213118|Desulfobacterales	28221|Deltaproteobacteria	T	HD domain	-	-	-	ko:K07814	-	-	-	-	ko00000,ko02022	-	-	-	HD,HD_5,Response_reg
k59_156668_1	335543.Sfum_3690	1.85e-38	147.0	COG2304@1|root,COG2304@2|Bacteria,1MW8K@1224|Proteobacteria,42NNC@68525|delta/epsilon subdivisions,2WKQW@28221|Deltaproteobacteria,2MQ7A@213462|Syntrophobacterales	1224|Proteobacteria	S	von Willebrand factor, type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	FecR,VIT,VWA_3
k59_3992_1	530564.Psta_3049	4.81e-42	142.0	2CGRW@1|root,33JMU@2|Bacteria,2J4DX@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_193841_1	1265505.ATUG01000001_gene3029	3.51e-16	76.3	COG0685@1|root,COG0685@2|Bacteria,1MXTZ@1224|Proteobacteria,42NTS@68525|delta/epsilon subdivisions,2WJQC@28221|Deltaproteobacteria,2MPSW@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Methylenetetrahydrofolate reductase	-	-	-	-	-	-	-	-	-	-	-	-	MTHFR
k59_193841_2	1265505.ATUG01000001_gene3028	4.11e-101	297.0	COG4656@1|root,COG4656@2|Bacteria,1MWAX@1224|Proteobacteria,42NJM@68525|delta/epsilon subdivisions,2WJJB@28221|Deltaproteobacteria,2MMJW@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Methylene-tetrahydrofolate reductase C terminal	-	-	-	-	-	-	-	-	-	-	-	-	MTHFR_C
k59_224331_1	933262.AXAM01000015_gene78	1.48e-91	279.0	COG1451@1|root,COG1451@2|Bacteria,1RDZ9@1224|Proteobacteria,42SB4@68525|delta/epsilon subdivisions,2WNVN@28221|Deltaproteobacteria,2MKE7@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF2786)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2786,SprT-like
k59_163711_1	1232437.KL662050_gene5395	7.32e-21	93.2	COG3829@1|root,COG3829@2|Bacteria,1MXSB@1224|Proteobacteria,42PHW@68525|delta/epsilon subdivisions,2WJSS@28221|Deltaproteobacteria,2MHWS@213118|Desulfobacterales	28221|Deltaproteobacteria	KT	Sigma-54 interaction domain	-	-	-	-	-	-	-	-	-	-	-	-	Sigma54_activat
k59_163711_2	390235.PputW619_3010	2.26e-15	78.6	COG2199@1|root,COG3706@2|Bacteria,1RCJQ@1224|Proteobacteria,1RQUA@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
k59_141529_1	933262.AXAM01000004_gene2402	1.16e-67	221.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,42Q67@68525|delta/epsilon subdivisions,2WKZ1@28221|Deltaproteobacteria,2MHTH@213118|Desulfobacterales	28221|Deltaproteobacteria	KLT	PFAM Protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	CHASE2,Pkinase
k59_202079_2	1280673.AUJJ01000040_gene11	2.43e-63	211.0	COG0517@1|root,COG0517@2|Bacteria,1TQ4J@1239|Firmicutes,24B68@186801|Clostridia,4BXRC@830|Butyrivibrio	186801|Clostridia	S	Putative transposase	-	-	-	-	-	-	-	-	-	-	-	-	Y2_Tnp,Zn_Tnp_IS91
k59_65128_1	1229172.JQFA01000002_gene4233	3.17e-58	187.0	COG3415@1|root,COG3415@2|Bacteria,1G802@1117|Cyanobacteria	1117|Cyanobacteria	L	Homeodomain-like domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_23,HTH_32
k59_49978_1	1538644.KO02_01635	3.89e-08	58.9	COG1040@1|root,COG1040@2|Bacteria,4NNI1@976|Bacteroidetes,1IRYV@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Phosphoribosyl transferase domain	comF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	Pribosyltran
k59_27035_1	338963.Pcar_2422	1.9e-38	135.0	COG0289@1|root,COG0289@2|Bacteria,1MUCT@1224|Proteobacteria,42N84@68525|delta/epsilon subdivisions,2WJKT@28221|Deltaproteobacteria,43THZ@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	Dihydrodipicolinate reductase, C-terminus	dapB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	-	DapB_C,DapB_N
k59_80871_1	335543.Sfum_2077	8.38e-170	490.0	COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,42P0M@68525|delta/epsilon subdivisions,2WJMC@28221|Deltaproteobacteria,2MR1W@213462|Syntrophobacterales	28221|Deltaproteobacteria	I	AMP-dependent synthetase and ligase	-	-	6.2.1.1,6.2.1.32	ko:K01895,ko:K08295	ko00010,ko00620,ko00627,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00627,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R00982,R01354	RC00004,RC00012,RC00043,RC00070,RC00174,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
k59_27043_1	264730.PSPPH_4794	2.92e-25	100.0	COG0693@1|root,COG0693@2|Bacteria,1MY0C@1224|Proteobacteria,1S3SC@1236|Gammaproteobacteria,1Z8DQ@136849|Pseudomonas syringae group	1236|Gammaproteobacteria	S	DJ-1/PfpI family	pfpI	-	3.5.1.124	ko:K05520	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DJ-1_PfpI
k59_58120_1	386456.JQKN01000008_gene1397	1.55e-18	80.9	COG0071@1|root,arCOG01838@2157|Archaea,2Y1IR@28890|Euryarchaeota	28890|Euryarchaeota	O	response to heat	-	-	-	-	-	-	-	-	-	-	-	-	HSP20
k59_73227_1	1125863.JAFN01000001_gene600	3.37e-96	285.0	COG1126@1|root,COG1126@2|Bacteria,1MU9Q@1224|Proteobacteria,42M0S@68525|delta/epsilon subdivisions,2WITR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	PFAM ABC transporter related	-	-	3.6.3.21	ko:K02028	-	M00236	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.3	-	-	ABC_tran
k59_193861_2	637910.ROD_47321	1.05e-44	159.0	COG4379@1|root,COG4379@2|Bacteria,1MX68@1224|Proteobacteria,1RYCD@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	tail protein	-	-	-	-	-	-	-	-	-	-	-	-	Phage_GPD
k59_65147_1	933262.AXAM01000052_gene2016	2.37e-90	280.0	COG2199@1|root,COG3706@2|Bacteria,1R8F2@1224|Proteobacteria,42QMA@68525|delta/epsilon subdivisions,2WKC1@28221|Deltaproteobacteria,2MHN4@213118|Desulfobacterales	28221|Deltaproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	DUF484,GGDEF
k59_163721_1	933262.AXAM01000142_gene2436	5.53e-118	358.0	COG0493@1|root,COG1148@1|root,COG0493@2|Bacteria,COG1148@2|Bacteria,1MU2H@1224|Proteobacteria,42M6X@68525|delta/epsilon subdivisions,2X6YD@28221|Deltaproteobacteria,2MHMN@213118|Desulfobacterales	28221|Deltaproteobacteria	E	PFAM Pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_20,Pyr_redox_2
k59_171607_2	132113.XP_003485606.1	5.19e-74	223.0	COG5262@1|root,KOG1756@2759|Eukaryota,3A1K0@33154|Opisthokonta,3BQBZ@33208|Metazoa,3D6DA@33213|Bilateria,41Z19@6656|Arthropoda,3SM7V@50557|Insecta,46I5V@7399|Hymenoptera	33208|Metazoa	B	Histone H2A	-	GO:0002376,GO:0006139,GO:0006259,GO:0006281,GO:0006355,GO:0006725,GO:0006807,GO:0006950,GO:0006952,GO:0006955,GO:0006974,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009617,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0033554,GO:0034641,GO:0042742,GO:0043170,GO:0043207,GO:0044237,GO:0044238,GO:0044260,GO:0045087,GO:0046483,GO:0050789,GO:0050794,GO:0050829,GO:0050896,GO:0051171,GO:0051252,GO:0051704,GO:0051707,GO:0051716,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0098542,GO:1901360,GO:1903506,GO:2000112,GO:2001141	-	ko:K11251	ko04217,ko05034,ko05322,map04217,map05034,map05322	-	-	-	ko00000,ko00001,ko03036,ko04147	-	-	-	Histone,Histone_H2A_C
k59_73231_1	335543.Sfum_1817	1.45e-51	180.0	COG0661@1|root,COG0661@2|Bacteria,1MU1Z@1224|Proteobacteria,42N87@68525|delta/epsilon subdivisions,2WK1B@28221|Deltaproteobacteria,2MRH3@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	ABC1 family	-	-	-	ko:K03688	-	-	-	-	ko00000	-	-	-	ABC1,RIO1
k59_216948_1	335543.Sfum_0821	6.49e-46	168.0	COG1148@1|root,COG2204@1|root,COG1148@2|Bacteria,COG2204@2|Bacteria,1QUM4@1224|Proteobacteria,42MPP@68525|delta/epsilon subdivisions,2WJ3U@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	4Fe-4S ferredoxin iron-sulfur binding domain protein	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,FAD_oxidored,Fer4,Fer4_7,NAD_binding_8,Pyr_redox_2,Response_reg
k59_171615_1	1207076.ALAT01000089_gene964	7.4e-63	209.0	COG1012@1|root,COG1012@2|Bacteria,1MUHV@1224|Proteobacteria,1RNFN@1236|Gammaproteobacteria,1Z09R@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	C	COG1012 NAD-dependent aldehyde dehydrogenases	mmsA	-	1.2.1.18,1.2.1.27	ko:K00140	ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200	M00013	R00705,R00706,R00922,R00935	RC00004,RC02723,RC02817	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
k59_65156_1	1131269.AQVV01000039_gene1546	3.96e-77	238.0	COG1290@1|root,COG1290@2|Bacteria	2|Bacteria	C	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_B_C,Cytochrome_B
k59_73241_2	458817.Shal_3043	7.15e-61	200.0	COG0076@1|root,COG0076@2|Bacteria,1MX25@1224|Proteobacteria,1RNSQ@1236|Gammaproteobacteria,2QBFQ@267890|Shewanellaceae	1236|Gammaproteobacteria	H	Belongs to the group II decarboxylase family	gadB	GO:0003674,GO:0003824,GO:0004351,GO:0006082,GO:0006520,GO:0006536,GO:0006807,GO:0008150,GO:0008152,GO:0009064,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0071704,GO:1901564,GO:1901605	4.1.1.15	ko:K01580	ko00250,ko00410,ko00430,ko00650,ko01100,ko01110,ko01120,ko02024,ko04727,ko04940,map00250,map00410,map00430,map00650,map01100,map01110,map01120,map02024,map04727,map04940	M00027	R00261,R00489,R01682,R02466	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Pyridoxal_deC
k59_141531_1	556261.HMPREF0240_04462	4.19e-24	101.0	COG1847@1|root,COG1847@2|Bacteria,1V3IN@1239|Firmicutes,249EA@186801|Clostridia,36F11@31979|Clostridiaceae	186801|Clostridia	S	R3H domain protein	jag	-	-	ko:K06346	-	-	-	-	ko00000	-	-	-	Jag_N,KH_4,R3H
k59_95853_1	522306.CAP2UW1_4031	1.59e-58	199.0	COG1253@1|root,COG1253@2|Bacteria,1MV3P@1224|Proteobacteria,2VHBA@28216|Betaproteobacteria,1KPY4@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	S	Domain of unknown function DUF21	-	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,DUF21
k59_111085_1	224324.aq_2053	3.47e-34	135.0	COG1200@1|root,COG1200@2|Bacteria,2G3KW@200783|Aquificae	200783|Aquificae	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
k59_4030_1	935845.JADQ01000014_gene3467	3.69e-58	200.0	COG1570@1|root,COG1570@2|Bacteria,1TP4E@1239|Firmicutes,4HAN2@91061|Bacilli,26QBK@186822|Paenibacillaceae	91061|Bacilli	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseA	-	3.1.11.6	ko:K03601	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
k59_19737_1	1172190.M947_09465	2.04e-30	114.0	COG3658@1|root,COG3658@2|Bacteria,1N28F@1224|Proteobacteria,42RSP@68525|delta/epsilon subdivisions,2YPDS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Dihaem cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	DHC
k59_65169_1	1265505.ATUG01000003_gene134	5.53e-12	67.8	COG1075@1|root,COG1075@2|Bacteria,1R5PK@1224|Proteobacteria,42ZS8@68525|delta/epsilon subdivisions,2WV2F@28221|Deltaproteobacteria,2MN8J@213118|Desulfobacterales	28221|Deltaproteobacteria	S	acetyltransferases and hydrolases with the alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_73251_1	1408444.JHYC01000001_gene1110	0.000788	41.2	COG1898@1|root,COG1898@2|Bacteria,1R9YD@1224|Proteobacteria,1S245@1236|Gammaproteobacteria,1JDEJ@118969|Legionellales	118969|Legionellales	G	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose	rmlC	-	5.1.3.13	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R06514	RC01531	ko00000,ko00001,ko00002,ko01000	-	-	-	dTDP_sugar_isom
k59_73251_2	96561.Dole_1011	1.76e-66	210.0	COG1209@1|root,COG1209@2|Bacteria,1MU0X@1224|Proteobacteria,42MTN@68525|delta/epsilon subdivisions,2WJAI@28221|Deltaproteobacteria,2MHRS@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis	rmlA	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
k59_118048_1	247490.KSU1_C0392	6.41e-124	377.0	COG0466@1|root,COG0466@2|Bacteria,2IYNA@203682|Planctomycetes	203682|Planctomycetes	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
k59_42247_1	335543.Sfum_3763	8.63e-86	262.0	COG3335@1|root,COG3415@1|root,COG3335@2|Bacteria,COG3415@2|Bacteria,1MW7X@1224|Proteobacteria	1224|Proteobacteria	L	COG3335 Transposase and inactivated derivatives	-	-	-	ko:K07494	-	-	-	-	ko00000	-	-	-	DDE_3,HTH_23,HTH_32,HTH_33
k59_178748_1	335543.Sfum_0855	8.32e-109	329.0	COG2256@1|root,COG2256@2|Bacteria,1MUVS@1224|Proteobacteria,42M9X@68525|delta/epsilon subdivisions,2WJ7E@28221|Deltaproteobacteria,2MQ8K@213462|Syntrophobacterales	28221|Deltaproteobacteria	L	PFAM MgsA AAA ATPase C terminal	rarA	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA,AAA_assoc_2,MgsA_C,RuvB_N
k59_12789_1	1167006.UWK_02393	9.25e-55	186.0	COG1624@1|root,COG4856@1|root,COG1624@2|Bacteria,COG4856@2|Bacteria,1PEQT@1224|Proteobacteria,42P5A@68525|delta/epsilon subdivisions,2WKPP@28221|Deltaproteobacteria,2MIQR@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria	dacA	-	-	-	-	-	-	-	-	-	-	-	DisA_N,YbbR
k59_202117_1	570967.JMLV01000002_gene1944	1.11e-31	120.0	COG0697@1|root,COG0697@2|Bacteria,1MZQM@1224|Proteobacteria,2TUPG@28211|Alphaproteobacteria,2JQS8@204441|Rhodospirillales	204441|Rhodospirillales	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
k59_4034_2	1280686.AUKE01000002_gene1280	2.45e-08	58.2	COG2200@1|root,COG5001@1|root,COG2200@2|Bacteria,COG5001@2|Bacteria,1TP8V@1239|Firmicutes,247PX@186801|Clostridia,4C28Z@830|Butyrivibrio	186801|Clostridia	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
k59_118057_1	521045.Kole_0419	6.88e-38	144.0	COG4412@1|root,COG4412@2|Bacteria,2GDTB@200918|Thermotogae	200918|Thermotogae	M	TIGRFAM M6 family metalloprotease domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M6
k59_35384_1	1125863.JAFN01000001_gene1617	5.57e-137	414.0	COG1226@1|root,COG4651@1|root,COG1226@2|Bacteria,COG4651@2|Bacteria,1MV34@1224|Proteobacteria,42MEM@68525|delta/epsilon subdivisions,2WK23@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family	-	-	-	ko:K03455,ko:K11747	-	-	-	-	ko00000,ko02000	2.A.37,2.A.37.1.2	-	-	Na_H_Exchanger,TrkA_C,TrkA_N
k59_19742_1	1379281.AVAG01000001_gene268	6.93e-184	524.0	COG5557@1|root,COG5557@2|Bacteria,1MWYI@1224|Proteobacteria,42N47@68525|delta/epsilon subdivisions,2WIKZ@28221|Deltaproteobacteria,2M8JX@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	PFAM Polysulphide reductase, NrfD	qrcD	-	-	ko:K00185	-	-	-	-	ko00000	5.A.3	-	-	NrfD
k59_42252_2	268739.Nmlp_2277	1.07e-12	72.4	arCOG02387@1|root,arCOG02387@2157|Archaea,2Y149@28890|Euryarchaeota,240V2@183963|Halobacteria	183963|Halobacteria	T	COG0784 FOG CheY-like receiver	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Response_reg
k59_13368_1	744980.TRICHSKD4_4797	5.03e-79	256.0	COG0330@1|root,COG0330@2|Bacteria,1MW1D@1224|Proteobacteria,2TRE5@28211|Alphaproteobacteria	28211|Alphaproteobacteria	O	SPFH domain / Band 7 family	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
k59_96382_1	1123321.KB905818_gene4750	3.95e-27	110.0	COG1028@1|root,COG1028@2|Bacteria,2GNM4@201174|Actinobacteria	201174|Actinobacteria	IQ	Short-chain dehydrogenase reductase sdr	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
k59_194353_2	1437882.AZRU01000081_gene6693	7.33e-14	73.6	COG4220@1|root,COG4220@2|Bacteria,1R3AU@1224|Proteobacteria,1T65U@1236|Gammaproteobacteria,1YKGN@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	L	transposase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_69320_1	439235.Dalk_5088	3.45e-40	148.0	COG2204@1|root,COG2204@2|Bacteria	2|Bacteria	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388,GGDEF,Response_reg
k59_145146_1	1265505.ATUG01000002_gene1161	2.08e-44	152.0	COG0407@1|root,COG0407@2|Bacteria,1PXIF@1224|Proteobacteria,42SKI@68525|delta/epsilon subdivisions,2WPBF@28221|Deltaproteobacteria,2MKAD@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
k59_145146_2	1121430.JMLG01000016_gene381	4.13e-14	67.8	COG0407@1|root,COG0407@2|Bacteria	2|Bacteria	H	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III	-	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
k59_175527_1	1232410.KI421412_gene178	4.68e-159	477.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2WJ8D@28221|Deltaproteobacteria,43S5E@69541|Desulfuromonadales	28221|Deltaproteobacteria	V	AcrB/AcrD/AcrF family	-	-	-	ko:K03296,ko:K18138	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
k59_16188_1	2423.NA23_0202905	1.04e-15	80.1	COG2262@1|root,COG2262@2|Bacteria,2GBX9@200918|Thermotogae	200918|Thermotogae	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
k59_198215_1	926569.ANT_04650	1.21e-35	133.0	COG0031@1|root,COG0031@2|Bacteria,2G8GE@200795|Chloroflexi	200795|Chloroflexi	E	Pyridoxal-phosphate dependent enzyme	-	-	-	-	-	-	-	-	-	-	-	-	PALP
k59_198215_2	1167006.UWK_01323	5.84e-15	75.1	COG0498@1|root,COG0498@2|Bacteria,1MUWQ@1224|Proteobacteria,42M1W@68525|delta/epsilon subdivisions,2WK53@28221|Deltaproteobacteria,2MIJV@213118|Desulfobacterales	28221|Deltaproteobacteria	E	TIGRFAM threonine synthase	-	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
k59_54179_1	1121943.KB899997_gene1708	1.67e-37	136.0	COG0473@1|root,COG0473@2|Bacteria,1MUH4@1224|Proteobacteria,1RRPI@1236|Gammaproteobacteria,1XNNF@135619|Oceanospirillales	135619|Oceanospirillales	CE	Tartrate dehydrogenase	tdh	-	1.1.1.83,1.1.1.93,4.1.1.73	ko:K07246	ko00630,ko00650,map00630,map00650	-	R00215,R01751,R02545,R06180	RC00084,RC00105,RC00594	ko00000,ko00001,ko01000	-	-	-	Iso_dh
k59_122447_1	1470591.BW41_02201	6.16e-18	79.7	COG5573@1|root,COG5573@2|Bacteria,1N3BU@1224|Proteobacteria,2U65X@28211|Alphaproteobacteria,2K7E0@204457|Sphingomonadales	204457|Sphingomonadales	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	-	-	-	-	-	-	-	-	-	PIN
k59_31435_1	706587.Desti_3019	1.02e-24	103.0	COG0673@1|root,COG1063@1|root,COG0673@2|Bacteria,COG1063@2|Bacteria,1PDZZ@1224|Proteobacteria,42M63@68525|delta/epsilon subdivisions,2WJDW@28221|Deltaproteobacteria,2MQXM@213462|Syntrophobacterales	28221|Deltaproteobacteria	E	PFAM Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	ADH_zinc_N,GFO_IDH_MocA
k59_69327_1	1280692.AUJL01000044_gene2346	3.88e-88	274.0	COG0553@1|root,COG0553@2|Bacteria,1TP2C@1239|Firmicutes,24DVA@186801|Clostridia,36FNM@31979|Clostridiaceae	186801|Clostridia	L	SNF2 family N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,N6_N4_Mtase,SNF2_N
k59_167782_1	356851.JOAN01000002_gene615	2.06e-28	115.0	COG2041@1|root,COG2041@2|Bacteria,2GMG2@201174|Actinobacteria,4D93Q@85008|Micromonosporales	201174|Actinobacteria	S	Mo-co oxidoreductase dimerisation domain	-	-	1.8.3.1	ko:K00387	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R00533	RC00168	ko00000,ko00001,ko01000	-	-	-	Mo-co_dimer,Oxidored_molyb
k59_8695_1	1121396.KB893077_gene738	1.13e-81	263.0	COG0438@1|root,COG0438@2|Bacteria,1R3Q9@1224|Proteobacteria,42MQ2@68525|delta/epsilon subdivisions,2WM1F@28221|Deltaproteobacteria,2MQ1W@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Glycosyl transferases group 1	-	-	2.4.1.345	ko:K08256	-	-	R11702	-	ko00000,ko01000,ko01003	-	GT4	-	Glyco_transf_4,Glycos_transf_1
k59_8695_2	1123008.KB905693_gene1166	2.99e-23	96.7	COG0438@1|root,COG0438@2|Bacteria,4NIP2@976|Bacteroidetes,2FQ2U@200643|Bacteroidia,22X1C@171551|Porphyromonadaceae	976|Bacteroidetes	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
k59_69339_1	706587.Desti_3270	5.59e-65	223.0	COG2202@1|root,COG2203@1|root,COG2204@1|root,COG4191@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG2204@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MC4@68525|delta/epsilon subdivisions,2WIU5@28221|Deltaproteobacteria,2MQZQ@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
k59_228543_2	1550073.JROH01000001_gene687	4.83e-31	119.0	COG0766@1|root,COG0766@2|Bacteria,1MUH7@1224|Proteobacteria,2TRPH@28211|Alphaproteobacteria,2K1H1@204457|Sphingomonadales	204457|Sphingomonadales	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
k59_152914_1	1125863.JAFN01000001_gene1443	4.11e-98	291.0	COG1136@1|root,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,43ADX@68525|delta/epsilon subdivisions,2WMPG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	PFAM ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
k59_61943_1	281687.CJA37273	3.14e-05	50.1	KOG0576@1|root,KOG0576@2759|Eukaryota,3AJ5W@33154|Opisthokonta,3BAP0@33208|Metazoa,3CRVB@33213|Bilateria,40AZY@6231|Nematoda,1KUE5@119089|Chromadorea,40SYS@6236|Rhabditida	33208|Metazoa	T	Belongs to the protein kinase superfamily. STE Ser Thr protein kinase family. STE20 subfamily	MAP4K1	GO:0000165,GO:0000166,GO:0000185,GO:0000187,GO:0001932,GO:0001934,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006915,GO:0006950,GO:0006996,GO:0007030,GO:0007154,GO:0007165,GO:0007254,GO:0007257,GO:0007346,GO:0007610,GO:0008144,GO:0008150,GO:0008152,GO:0008219,GO:0008283,GO:0008349,GO:0008361,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009636,GO:0009893,GO:0009966,GO:0009967,GO:0009968,GO:0009987,GO:0010033,GO:0010256,GO:0010562,GO:0010604,GO:0010646,GO:0010647,GO:0010648,GO:0010941,GO:0010942,GO:0012501,GO:0016043,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0017124,GO:0018105,GO:0018193,GO:0018209,GO:0019220,GO:0019222,GO:0019538,GO:0019904,GO:0023014,GO:0023051,GO:0023052,GO:0023056,GO:0023057,GO:0030534,GO:0030554,GO:0031098,GO:0031323,GO:0031325,GO:0031399,GO:0031401,GO:0032006,GO:0032008,GO:0032147,GO:0032268,GO:0032270,GO:0032501,GO:0032535,GO:0032553,GO:0032555,GO:0032559,GO:0032872,GO:0032874,GO:0033554,GO:0033674,GO:0033993,GO:0034097,GO:0034612,GO:0035330,GO:0035332,GO:0035556,GO:0035639,GO:0035690,GO:0036094,GO:0036211,GO:0040008,GO:0040009,GO:0042058,GO:0042059,GO:0042221,GO:0042325,GO:0042327,GO:0042493,GO:0042592,GO:0042981,GO:0043065,GO:0043067,GO:0043068,GO:0043085,GO:0043167,GO:0043168,GO:0043170,GO:0043405,GO:0043406,GO:0043408,GO:0043410,GO:0043412,GO:0043506,GO:0043507,GO:0043549,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0045471,GO:0045793,GO:0045859,GO:0045860,GO:0045937,GO:0046328,GO:0046330,GO:0046677,GO:0046777,GO:0048149,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048584,GO:0048585,GO:0048878,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051174,GO:0051246,GO:0051247,GO:0051338,GO:0051347,GO:0051403,GO:0051716,GO:0051726,GO:0055088,GO:0055090,GO:0060255,GO:0065007,GO:0065008,GO:0065009,GO:0070302,GO:0070304,GO:0070328,GO:0070887,GO:0071310,GO:0071396,GO:0071704,GO:0071840,GO:0071900,GO:0071902,GO:0080090,GO:0080134,GO:0080135,GO:0090066,GO:0097159,GO:0097305,GO:0097306,GO:0097327,GO:0097367,GO:0140096,GO:1901184,GO:1901185,GO:1901265,GO:1901363,GO:1901564,GO:1901654,GO:1901655,GO:1901700,GO:1901701,GO:1902531,GO:1902533,GO:1903432,GO:1904263,GO:1904627,GO:1904628	2.7.11.1	ko:K04406,ko:K04408,ko:K08833	ko04010,map04010	-	-	-	ko00000,ko00001,ko01000,ko01001	-	-	-	CNH,Pkinase
k59_39084_1	1000565.METUNv1_00006	5.05e-121	360.0	COG3039@1|root,COG3039@2|Bacteria,1MUVI@1224|Proteobacteria,2VK9J@28216|Betaproteobacteria,2KUE1@206389|Rhodocyclales	206389|Rhodocyclales	L	COG3666 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DUF772
k59_130089_1	555779.Dthio_PD1799	1.13e-58	206.0	COG1924@1|root,COG3580@1|root,COG1924@2|Bacteria,COG3580@2|Bacteria,1PKG6@1224|Proteobacteria,42MY4@68525|delta/epsilon subdivisions,2WJFI@28221|Deltaproteobacteria,2M8T9@213115|Desulfovibrionales	28221|Deltaproteobacteria	I	ATPase BadF BadG BcrA BcrD type	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG,DUF2229
k59_99686_1	867845.KI911784_gene1341	4.55e-134	397.0	COG0675@1|root,COG0675@2|Bacteria,2G823@200795|Chloroflexi,3779K@32061|Chloroflexia	32061|Chloroflexia	L	Putative transposase DNA-binding domain	-	-	-	ko:K07496	-	-	-	-	ko00000	-	-	-	HTH_OrfB_IS605,OrfB_IS605,OrfB_Zn_ribbon
k59_99686_2	1002339.HMPREF9373_1118	7.93e-26	100.0	COG2452@1|root,COG2452@2|Bacteria,1QV30@1224|Proteobacteria,1S2GA@1236|Gammaproteobacteria,3NJJA@468|Moraxellaceae	1236|Gammaproteobacteria	L	Resolvase, N terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MerR,Resolvase
k59_31464_1	880072.Desac_0816	1.36e-93	286.0	COG0247@1|root,COG0247@2|Bacteria,1N5Q2@1224|Proteobacteria,42P5D@68525|delta/epsilon subdivisions,2WJ9I@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM Cysteine-rich	-	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_17
k59_137631_1	1121396.KB892920_gene51	5.3e-21	92.0	COG0404@1|root,COG0446@1|root,COG0404@2|Bacteria,COG0446@2|Bacteria,1MVEK@1224|Proteobacteria,42P3Z@68525|delta/epsilon subdivisions,2WKRN@28221|Deltaproteobacteria,2MJ14@213118|Desulfobacterales	28221|Deltaproteobacteria	C	2Fe-2S iron-sulfur cluster binding domain	-	-	1.5.3.1	ko:K00302	ko00260,ko01100,map00260,map01100	-	R00610	RC00060,RC00557	ko00000,ko00001,ko01000	-	-	-	Fer2_4,Fer2_BFD,GCV_T,GCV_T_C,Pyr_redox_2
k59_137631_2	1121405.dsmv_1464	3.1e-32	118.0	2C345@1|root,2ZNZ7@2|Bacteria,1RFJQ@1224|Proteobacteria,42RNP@68525|delta/epsilon subdivisions,2WNQN@28221|Deltaproteobacteria,2MJWB@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Aminomethyltransferase folate-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GCV_T
k59_54209_1	96561.Dole_3040	7.11e-95	286.0	COG0016@1|root,COG0016@2|Bacteria,1MVD7@1224|Proteobacteria,42MB0@68525|delta/epsilon subdivisions,2WJ42@28221|Deltaproteobacteria,2MI3B@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily	pheS	GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iAF987.Gmet_1415	Phe_tRNA-synt_N,tRNA-synt_2d
k59_205915_2	1128398.Curi_c29330	2.71e-27	108.0	COG1526@1|root,COG1526@2|Bacteria,1TU8R@1239|Firmicutes,24G61@186801|Clostridia,26B8F@186813|unclassified Clostridiales	186801|Clostridia	C	FdhD/NarQ family	fdhD	-	-	ko:K02379	-	-	-	-	ko00000	-	-	-	FdhD-NarQ
k59_122480_1	335543.Sfum_1754	3.69e-20	87.4	COG1277@1|root,COG1277@2|Bacteria,1NZZ9@1224|Proteobacteria,42SH9@68525|delta/epsilon subdivisions,2WPWW@28221|Deltaproteobacteria,2MRMI@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC2_membrane_3,ABC_transp_aux
k59_122480_2	335543.Sfum_1753	2.8e-39	145.0	COG3225@1|root,COG3225@2|Bacteria,1MUXW@1224|Proteobacteria,42MRY@68525|delta/epsilon subdivisions,2WJ4F@28221|Deltaproteobacteria,2MRB3@213462|Syntrophobacterales	28221|Deltaproteobacteria	P	transport system involved in gliding motility auxiliary component-like	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC_transp_aux
k59_160493_1	1122212.AULO01000010_gene328	2.36e-06	55.1	COG2931@1|root,COG5276@1|root,COG2931@2|Bacteria,COG5276@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF4347,FG-GAP,HemolysinCabind,PPC,Peptidase_S8,TSP_3
k59_221142_1	555779.Dthio_PD1393	8.41e-20	89.4	COG0661@1|root,COG0661@2|Bacteria,1MU1Z@1224|Proteobacteria,42N87@68525|delta/epsilon subdivisions,2WK1B@28221|Deltaproteobacteria,2MAFI@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	pfam abc1	-	-	-	ko:K03688	-	-	-	-	ko00000	-	-	-	ABC1,APH
k59_221142_2	314278.NB231_06211	4.66e-21	84.3	2EGMT@1|root,33ADY@2|Bacteria,1NH3I@1224|Proteobacteria,1SGAI@1236|Gammaproteobacteria,1WZTM@135613|Chromatiales	135613|Chromatiales	S	Phospholipase_D-nuclease N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	PLDc_N
k59_122485_1	439235.Dalk_2779	7.82e-51	169.0	COG0685@1|root,COG0685@2|Bacteria,1MXTZ@1224|Proteobacteria,42NTS@68525|delta/epsilon subdivisions,2WK04@28221|Deltaproteobacteria,2MIIA@213118|Desulfobacterales	28221|Deltaproteobacteria	E	PFAM Methylenetetrahydrofolate reductase	-	-	1.5.1.20,2.1.1.10	ko:K00297,ko:K00547	ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523	M00377	R00650,R01224,R07168	RC00003,RC00035,RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR
k59_39094_1	933262.AXAM01000005_gene2507	1.44e-35	131.0	COG0455@1|root,COG0455@2|Bacteria,1R8IW@1224|Proteobacteria,42PF7@68525|delta/epsilon subdivisions,2WJB5@28221|Deltaproteobacteria,2MIVC@213118|Desulfobacterales	28221|Deltaproteobacteria	D	Belongs to the ParA family	flhG	-	-	ko:K04562	-	-	-	-	ko00000,ko02035	-	-	-	AAA_31,CbiA,ParA
k59_137645_1	879212.DespoDRAFT_00606	3.18e-16	84.0	COG1766@1|root,COG1766@2|Bacteria,1MUQR@1224|Proteobacteria,42N04@68525|delta/epsilon subdivisions,2WJS0@28221|Deltaproteobacteria,2MHWU@213118|Desulfobacterales	28221|Deltaproteobacteria	N	The M ring may be actively involved in energy transduction	fliF	-	-	ko:K02409	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	YscJ_FliF,YscJ_FliF_C
k59_39098_1	290315.Clim_1949	3.23e-67	231.0	COG0642@1|root,COG5002@1|root,COG0642@2|Bacteria,COG2205@2|Bacteria,COG5002@2|Bacteria,1FDBJ@1090|Chlorobi	1090|Chlorobi	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,PAS_3,Response_reg,dCache_3
k59_236270_1	797210.Halxa_1270	3.43e-28	124.0	COG2202@1|root,COG2203@1|root,COG3413@1|root,arCOG02329@1|root,arCOG02348@1|root,arCOG02352@1|root,arCOG02276@2157|Archaea,arCOG02329@2157|Archaea,arCOG02334@2157|Archaea,arCOG02348@2157|Archaea,arCOG02352@2157|Archaea,arCOG02369@2157|Archaea,2XTCA@28890|Euryarchaeota,23S6Z@183963|Halobacteria	183963|Halobacteria	T	COG2202 FOG PAS PAC domain	-	-	-	-	-	-	-	-	-	-	-	-	BAT,GAF_2,HTH_10,PAS_3,PAS_4,PAS_9
k59_228569_1	1121405.dsmv_1067	2.3e-38	137.0	COG0496@1|root,COG0496@2|Bacteria,1MVHE@1224|Proteobacteria,42N0I@68525|delta/epsilon subdivisions,2WMUX@28221|Deltaproteobacteria,2MJHY@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates	surE	-	3.1.3.5	ko:K03787	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	SurE
k59_99700_1	1499967.BAYZ01000009_gene5391	1.14e-111	343.0	COG2766@1|root,COG2766@2|Bacteria	2|Bacteria	T	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	AAA_PrkA,PrkA
k59_8733_1	1216932.CM240_3182	6.14e-11	68.2	COG0348@1|root,COG0348@2|Bacteria,1TPHF@1239|Firmicutes,247KH@186801|Clostridia	186801|Clostridia	C	4Fe-4S binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_5,Fer4_9
k59_39100_1	194439.CT0867	4.81e-93	297.0	COG1148@1|root,COG1908@1|root,COG1148@2|Bacteria,COG1908@2|Bacteria,1FEM4@1090|Chlorobi	1090|Chlorobi	C	Methyl-viologen-reducing hydrogenase, delta subunit	-	-	-	ko:K16886	-	-	-	-	ko00000	-	-	-	Fer4_9,FlpD,Pyr_redox_2
k59_61971_1	59919.PMM1416	8.32e-92	288.0	COG2931@1|root,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin,DUF4114,HemolysinCabind,PA14
k59_39103_2	1499967.BAYZ01000014_gene6360	2.23e-83	266.0	COG5012@1|root,COG5012@2|Bacteria	2|Bacteria	T	cobalamin binding	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding
k59_236278_1	1047013.AQSP01000106_gene1765	1.39e-94	288.0	COG1509@1|root,COG1509@2|Bacteria,2NNY6@2323|unclassified Bacteria	2|Bacteria	E	lysine 2,3-aminomutase activity	kamA	-	5.4.3.2,5.4.3.9	ko:K01843,ko:K19810,ko:K19814	ko00310,map00310	-	R00461	RC00303	ko00000,ko00001,ko01000,ko03012	-	-	-	Fer4_12,Fer4_14,LAM_C,Radical_SAM
k59_114845_1	269799.Gmet_2618	7.59e-54	179.0	COG0363@1|root,COG0363@2|Bacteria,1R5K6@1224|Proteobacteria,42UV6@68525|delta/epsilon subdivisions,2WP1R@28221|Deltaproteobacteria,43TFM@69541|Desulfuromonadales	28221|Deltaproteobacteria	G	Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase	pgl	-	3.1.1.31	ko:K01057	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	M00004,M00006,M00008	R02035	RC00537	ko00000,ko00001,ko00002,ko01000	-	-	-	Glucosamine_iso
k59_221624_1	1499967.BAYZ01000154_gene1466	7.08e-58	197.0	COG0699@1|root,COG0699@2|Bacteria	2|Bacteria	T	ATPase. Has a role at an early stage in the morphogenesis of the spore coat	-	-	-	-	-	-	-	-	-	-	-	-	Dynamin_N
k59_1562_2	1121396.KB893079_gene878	1.78e-26	101.0	COG1837@1|root,COG1837@2|Bacteria	2|Bacteria	L	Belongs to the UPF0109 family	CP_0026	-	-	ko:K06960	-	-	-	-	ko00000	-	-	-	KH_4
k59_84962_1	1122947.FR7_0819	4.15e-28	112.0	COG2207@1|root,COG2207@2|Bacteria,1TPNZ@1239|Firmicutes,4H55K@909932|Negativicutes	909932|Negativicutes	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
k59_39639_1	429009.Adeg_0542	8.86e-05	45.1	COG3027@1|root,COG3027@2|Bacteria	2|Bacteria	D	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division	zapA	-	-	ko:K09888	-	-	-	-	ko00000,ko03036	-	-	-	ZapA
k59_100296_1	335543.Sfum_1572	1.34e-81	245.0	COG0098@1|root,COG0098@2|Bacteria,1MUS4@1224|Proteobacteria,42QX0@68525|delta/epsilon subdivisions,2WNBN@28221|Deltaproteobacteria,2MRKN@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	Belongs to the universal ribosomal protein uS5 family	rpsE	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02988	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S5,Ribosomal_S5_C
k59_77651_1	1121405.dsmv_0315	1.32e-131	383.0	COG1883@1|root,COG1883@2|Bacteria,1MV0G@1224|Proteobacteria,42MH1@68525|delta/epsilon subdivisions,2WJD7@28221|Deltaproteobacteria,2MIY0@213118|Desulfobacterales	28221|Deltaproteobacteria	C	TIGRFAM sodium ion-translocating decarboxylase, beta subunit	-	-	4.1.1.3	ko:K01572	ko00620,ko01100,map00620,map01100	-	R00217	RC00040	ko00000,ko00001,ko01000,ko02000	3.B.1.1.1	-	-	OAD_beta
k59_1571_1	933262.AXAM01000013_gene1293	2.82e-13	69.7	COG0206@1|root,COG0206@2|Bacteria,1MV2X@1224|Proteobacteria,42MHK@68525|delta/epsilon subdivisions,2WJAZ@28221|Deltaproteobacteria,2MHTR@213118|Desulfobacterales	28221|Deltaproteobacteria	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
k59_1571_2	290397.Adeh_3640	1.47e-38	144.0	COG1032@1|root,COG1032@2|Bacteria,1MU15@1224|Proteobacteria,42N12@68525|delta/epsilon subdivisions,2WK0X@28221|Deltaproteobacteria,2Z2X2@29|Myxococcales	28221|Deltaproteobacteria	C	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
k59_107737_1	1121396.KB893116_gene3131	2.05e-84	251.0	COG3542@1|root,COG3542@2|Bacteria,1RHBE@1224|Proteobacteria,42T2P@68525|delta/epsilon subdivisions,2WPQ3@28221|Deltaproteobacteria,2MKI3@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Cupin superfamily (DUF985)	-	-	-	ko:K09705	-	-	-	-	ko00000	-	-	-	Cupin_5
k59_160983_1	1286632.P278_33320	2.13e-20	90.5	2C852@1|root,32YB2@2|Bacteria,4NM63@976|Bacteroidetes,1I1C4@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4136)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4136
k59_47234_1	1379698.RBG1_1C00001G1740	3.66e-47	173.0	COG3852@1|root,COG3852@2|Bacteria	2|Bacteria	T	phosphorelay sensor kinase activity	-	-	2.7.13.3	ko:K02668	ko02020,map02020	M00501	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_8,PAS_9
k59_62472_1	880072.Desac_0499	6e-51	173.0	COG1804@1|root,COG1804@2|Bacteria,1MU2K@1224|Proteobacteria,42NP0@68525|delta/epsilon subdivisions,2WVG4@28221|Deltaproteobacteria,2MRQ6@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	L-carnitine dehydratase bile acid-inducible protein F	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
k59_62472_2	880072.Desac_0498	2.68e-42	141.0	2F0YS@1|root,33U0E@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_153487_1	1168065.DOK_08649	3.82e-11	70.1	COG0642@1|root,COG0642@2|Bacteria,1NTJ3@1224|Proteobacteria,1SN02@1236|Gammaproteobacteria,1J9UP@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	T	PAS fold	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_9
k59_1574_1	644282.Deba_2124	1.28e-82	260.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42NWT@68525|delta/epsilon subdivisions,2X5DA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Sigma-54 interaction domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
k59_1574_2	1167006.UWK_02670	6.33e-30	119.0	COG0477@1|root,COG2814@2|Bacteria,1R9V9@1224|Proteobacteria,42Q1C@68525|delta/epsilon subdivisions,2WK7P@28221|Deltaproteobacteria,2MMQA@213118|Desulfobacterales	28221|Deltaproteobacteria	EGP	Major Facilitator Superfamily	-	-	-	ko:K02575	ko00910,map00910	M00615	-	-	ko00000,ko00001,ko00002,ko02000	2.A.1.8	-	-	MFS_1
k59_154825_2	754477.Q7C_666	6.89e-05	47.0	COG0160@1|root,COG0160@2|Bacteria,1MWY6@1224|Proteobacteria,1RQKU@1236|Gammaproteobacteria,45ZS5@72273|Thiotrichales	72273|Thiotrichales	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.76	ko:K00836	ko00260,ko01100,ko01120,ko01210,ko01230,map00260,map01100,map01120,map01210,map01230	M00033	R06977	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
k59_108934_1	1232410.KI421417_gene2773	3.07e-42	160.0	COG4388@1|root,COG4388@2|Bacteria,1RA2J@1224|Proteobacteria,42S1P@68525|delta/epsilon subdivisions,2WNAJ@28221|Deltaproteobacteria,43VGV@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Mu-like prophage I protein	-	-	-	-	-	-	-	-	-	-	-	-	Mu-like_Pro
k59_108934_2	643562.Daes_2403	1.67e-18	88.2	2CDSP@1|root,32RYD@2|Bacteria,1N213@1224|Proteobacteria,42U4H@68525|delta/epsilon subdivisions,2WQTU@28221|Deltaproteobacteria,2MDKW@213115|Desulfovibrionales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_108934_3	1028801.RG1141_CH24140	8.1e-69	223.0	COG4397@1|root,COG4397@2|Bacteria,1MWX8@1224|Proteobacteria,2U0B4@28211|Alphaproteobacteria,4BC6J@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Mu-like prophage major head subunit gpT	-	-	-	-	-	-	-	-	-	-	-	-	Mu-like_gpT
k59_108934_5	371042.NG99_04605	3.74e-14	72.4	COG4387@1|root,COG4387@2|Bacteria,1N1K0@1224|Proteobacteria,1S9W3@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Mu-like prophage protein GP36	-	-	-	-	-	-	-	-	-	-	-	-	DUF1320
k59_108934_6	882.DVU_1114	7.56e-08	55.8	COG5005@1|root,COG5005@2|Bacteria,1N6UC@1224|Proteobacteria,42VJB@68525|delta/epsilon subdivisions,2WSEP@28221|Deltaproteobacteria,2MD3X@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	TIGRFAM phage virion morphogenesis	-	-	-	-	-	-	-	-	-	-	-	-	Phage_tail_S
k59_108934_9	296591.Bpro_3741	2.18e-138	414.0	COG4386@1|root,COG4386@2|Bacteria,1MXZD@1224|Proteobacteria,2VKVD@28216|Betaproteobacteria,4AH5R@80864|Comamonadaceae	28216|Betaproteobacteria	S	Phage tail sheath C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Phage_sheath_1,Phage_sheath_1C
k59_192401_1	1094980.Mpsy_0445	5.93e-33	127.0	COG2195@1|root,arCOG05229@2157|Archaea,2Y380@28890|Euryarchaeota,2NAGH@224756|Methanomicrobia	224756|Methanomicrobia	E	Peptidase family M20/M25/M40	-	-	-	ko:K01270	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M20
k59_56211_1	469371.Tbis_1992	8.58e-54	182.0	COG0126@1|root,COG0126@2|Bacteria,2GJC6@201174|Actinobacteria,4DX3T@85010|Pseudonocardiales	201174|Actinobacteria	G	Belongs to the phosphoglycerate kinase family	pgk	GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044464,GO:0071944	2.7.2.3,5.3.1.1	ko:K00927,ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01015,R01512	RC00002,RC00043,RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
k59_116440_1	933262.AXAM01000017_gene3141	1.35e-94	288.0	COG1150@1|root,COG1150@2|Bacteria,1QWNB@1224|Proteobacteria,43BTA@68525|delta/epsilon subdivisions,2X741@28221|Deltaproteobacteria,2MI1V@213118|Desulfobacterales	28221|Deltaproteobacteria	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_22
k59_131937_1	1232437.KL662000_gene4731	3.15e-39	140.0	COG0604@1|root,COG0604@2|Bacteria,1MV3W@1224|Proteobacteria,42MXJ@68525|delta/epsilon subdivisions,2WKAC@28221|Deltaproteobacteria,2MJ1T@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Zinc-binding dehydrogenase	acuI	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
k59_131937_2	1167006.UWK_02199	1.18e-33	120.0	COG3467@1|root,COG3467@2|Bacteria,1N4RH@1224|Proteobacteria,42TKQ@68525|delta/epsilon subdivisions,2WQ06@28221|Deltaproteobacteria,2MKN9@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	ko:K07005	-	-	-	-	ko00000	-	-	-	Pyridox_ox_2
k59_48341_1	1232437.KL662016_gene1034	4.68e-49	167.0	COG5653@1|root,COG5653@2|Bacteria,1MV00@1224|Proteobacteria,42PW5@68525|delta/epsilon subdivisions,2WKPE@28221|Deltaproteobacteria,2MIEF@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_6
k59_2736_1	1487923.DP73_12740	1.87e-13	68.9	COG0376@1|root,COG0376@2|Bacteria,1TQDA@1239|Firmicutes,24DM7@186801|Clostridia,260RF@186807|Peptococcaceae	186801|Clostridia	P	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity	katG	-	1.11.1.21	ko:K03782	ko00360,ko00380,ko00940,ko00983,ko01100,ko01110,map00360,map00380,map00940,map00983,map01100,map01110	-	R00602,R00698,R02596,R02670,R03919,R04007,R07443,R11906	RC00034,RC00213,RC00767,RC02141	ko00000,ko00001,ko01000	-	-	-	peroxidase
k59_17976_1	913865.DOT_4450	9.05e-46	169.0	COG0659@1|root,COG0659@2|Bacteria,1TPI4@1239|Firmicutes,24978@186801|Clostridia,260IT@186807|Peptococcaceae	186801|Clostridia	U	PFAM Sulfate transporter	sulP	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
k59_78963_1	1343158.SACS_0382	1.34e-11	68.2	COG1538@1|root,COG1538@2|Bacteria,1MUA8@1224|Proteobacteria,2TSN8@28211|Alphaproteobacteria	28211|Alphaproteobacteria	MU	RND efflux system, outer membrane lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
k59_78963_2	667014.Thein_0138	1.94e-49	167.0	COG1309@1|root,COG1309@2|Bacteria,2GIHE@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	K	Domain of unknown function (DUF1956)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1956,TetR_N
k59_71056_1	335543.Sfum_2527	2.87e-89	285.0	COG0013@1|root,COG0013@2|Bacteria,1MU9A@1224|Proteobacteria,42M70@68525|delta/epsilon subdivisions,2WJA8@28221|Deltaproteobacteria,2MQ85@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
k59_40854_1	886293.Sinac_2777	7.24e-110	343.0	COG3119@1|root,COG3119@2|Bacteria,2IX0Y@203682|Planctomycetes	203682|Planctomycetes	P	PFAM sulfatase	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
k59_2749_1	880072.Desac_2296	9.82e-61	209.0	COG1480@1|root,COG1480@2|Bacteria,1NCY5@1224|Proteobacteria,42MI9@68525|delta/epsilon subdivisions,2WJI1@28221|Deltaproteobacteria,2MR04@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	7TM-HD extracellular	-	-	-	ko:K07037	-	-	-	-	ko00000	-	-	-	7TM-7TMR_HD,7TMR-HDED,HD
k59_116453_1	12360.Q38045_BPPHA	1.33e-05	55.5	4QAQE@10239|Viruses,4QUYF@35237|dsDNA viruses  no RNA stage,4QPDM@28883|Caudovirales,4QKN9@10699|Siphoviridae	10699|Siphoviridae	S	Phage integrase family	-	GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0015074,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:1901360	-	-	-	-	-	-	-	-	-	-	-
k59_207911_1	1172188.KB911823_gene513	8.19e-07	51.6	COG2047@1|root,COG2047@2|Bacteria,2I2H9@201174|Actinobacteria,4FFKZ@85021|Intrasporangiaceae	201174|Actinobacteria	S	Carboxylate--amine ligase	-	-	-	-	-	-	-	-	-	-	-	-	PAC2
k59_108956_1	888059.HMPREF9071_2314	1.19e-44	154.0	COG0020@1|root,COG0020@2|Bacteria,4NF2B@976|Bacteroidetes,1HXRP@117743|Flavobacteriia,1EQBN@1016|Capnocytophaga	976|Bacteroidetes	H	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	uppS	GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
k59_185312_1	1403313.AXBR01000023_gene2520	5.86e-06	51.6	COG0745@1|root,COG0745@2|Bacteria,1UX1V@1239|Firmicutes,4HD2J@91061|Bacilli,1ZDIX@1386|Bacillus	91061|Bacilli	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
k59_169700_2	1265505.ATUG01000003_gene516	4.58e-56	184.0	COG0589@1|root,COG0589@2|Bacteria,1RJMY@1224|Proteobacteria,439UF@68525|delta/epsilon subdivisions,2X583@28221|Deltaproteobacteria,2MMT1@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
k59_86587_1	335543.Sfum_4046	4.75e-16	71.6	COG1146@1|root,COG1146@2|Bacteria,1QWQ4@1224|Proteobacteria,43BUY@68525|delta/epsilon subdivisions,2X75X@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_7
k59_86587_2	1121406.JAEX01000011_gene2027	4.32e-11	57.8	COG1146@1|root,COG1146@2|Bacteria,1QWQ4@1224|Proteobacteria,43BUY@68525|delta/epsilon subdivisions,2X75X@28221|Deltaproteobacteria,2MHB0@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_7
k59_215516_1	509191.AEDB02000067_gene845	2.32e-07	52.0	COG2360@1|root,COG2360@2|Bacteria,1UY1P@1239|Firmicutes,248TU@186801|Clostridia,3WJ75@541000|Ruminococcaceae	186801|Clostridia	O	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine	aat	-	2.3.2.6	ko:K00684	-	-	R03813,R11443,R11444	RC00055,RC00064	ko00000,ko01000	-	-	-	Leu_Phe_trans
k59_215516_2	933262.AXAM01000015_gene82	2.35e-82	265.0	COG0542@1|root,COG0542@2|Bacteria,1MV8B@1224|Proteobacteria,42M2T@68525|delta/epsilon subdivisions,2WJ2W@28221|Deltaproteobacteria,2MHMB@213118|Desulfobacterales	28221|Deltaproteobacteria	O	ATP-dependent Clp protease ATP-binding subunit ClpA	clpA	-	-	ko:K03694	-	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
k59_132363_2	1196028.ALEF01000014_gene2707	2.61e-10	63.5	COG0305@1|root,COG0305@2|Bacteria,1TPCT@1239|Firmicutes,4H9Y8@91061|Bacilli,4C5ET@84406|Virgibacillus	91061|Bacilli	L	DnaB-like helicase C terminal domain	dnaB	GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0032392,GO:0032508,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
k59_170129_1	1047013.AQSP01000144_gene863	0.000138	45.4	COG0110@1|root,COG0110@2|Bacteria,2NQ73@2323|unclassified Bacteria	2|Bacteria	S	Bacterial transferase hexapeptide (six repeats)	-	-	2.3.1.18,2.3.1.79	ko:K00633,ko:K00661	-	-	-	-	ko00000,ko01000	-	-	-	Hexapep,Hexapep_2
k59_170129_2	118161.KB235922_gene3800	3.18e-05	47.4	COG2244@1|root,COG2244@2|Bacteria,1G2BA@1117|Cyanobacteria,3VHQ7@52604|Pleurocapsales	1117|Cyanobacteria	S	Membrane protein involved in the export of O-antigen and teichoic acid	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_C
k59_170131_1	909663.KI867150_gene940	3.88e-36	127.0	COG2893@1|root,COG2893@2|Bacteria,1RHH7@1224|Proteobacteria,42SST@68525|delta/epsilon subdivisions,2WPWN@28221|Deltaproteobacteria,2MQJY@213462|Syntrophobacterales	28221|Deltaproteobacteria	G	PTS system fructose IIA component	-	-	2.7.1.191	ko:K02793	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	M00276	R02630	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.6.1	-	-	EIIA-man
k59_94356_1	96561.Dole_2208	1.94e-40	145.0	COG1729@1|root,COG1729@2|Bacteria,1MUSV@1224|Proteobacteria,42P32@68525|delta/epsilon subdivisions,2WM9Q@28221|Deltaproteobacteria,2MISR@213118|Desulfobacterales	28221|Deltaproteobacteria	D	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division	cpoB	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6
k59_41229_1	933262.AXAM01000011_gene1733	2.34e-61	204.0	COG1236@1|root,COG1236@2|Bacteria,1MUDD@1224|Proteobacteria,42N91@68525|delta/epsilon subdivisions,2WIMM@28221|Deltaproteobacteria,2MIKE@213118|Desulfobacterales	28221|Deltaproteobacteria	J	RNA-metabolising metallo-beta-lactamase	-	-	-	ko:K07576	-	-	-	-	ko00000	-	-	-	Beta-Casp,Lactamase_B,Lactamase_B_6,RMMBL
k59_25945_1	243231.GSU2599	7.75e-145	420.0	COG3547@1|root,COG3547@2|Bacteria,1NGR7@1224|Proteobacteria,42NNQ@68525|delta/epsilon subdivisions,2WM2H@28221|Deltaproteobacteria,43TYM@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_185757_1	941449.dsx2_2960	1.01e-90	279.0	COG1148@1|root,COG1148@2|Bacteria,1R99M@1224|Proteobacteria,42Q2T@68525|delta/epsilon subdivisions,2WJTB@28221|Deltaproteobacteria,2MEIA@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Pyr_redox_2
k59_125040_1	1296416.JACB01000052_gene2812	2.2e-22	101.0	COG4251@1|root,COG4251@2|Bacteria,4PM7A@976|Bacteroidetes,1IJK9@117743|Flavobacteriia,2YM57@290174|Aquimarina	976|Bacteroidetes	T	PAS domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HNOBA,HisKA,PAS_3,PAS_9,Response_reg
k59_125040_2	1121445.ATUZ01000011_gene621	1.67e-40	141.0	COG0589@1|root,COG0589@2|Bacteria,1RA7K@1224|Proteobacteria,42V2P@68525|delta/epsilon subdivisions,2WRFB@28221|Deltaproteobacteria,2MBG2@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	Universal stress protein	usp-2	-	-	ko:K06149	-	-	-	-	ko00000	-	-	-	Usp
k59_125040_3	335543.Sfum_0650	3.43e-81	255.0	COG0589@1|root,COG0589@2|Bacteria,1REA3@1224|Proteobacteria,42RXY@68525|delta/epsilon subdivisions,2WNM6@28221|Deltaproteobacteria,2MSDJ@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	PFAM UspA domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
k59_86593_1	1121405.dsmv_1036	9.39e-85	273.0	COG0653@1|root,COG0653@2|Bacteria,1MUJZ@1224|Proteobacteria,42MMV@68525|delta/epsilon subdivisions,2WIZ4@28221|Deltaproteobacteria,2MIJD@213118|Desulfobacterales	28221|Deltaproteobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	Helicase_C,SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
k59_33741_1	96561.Dole_2586	1.09e-90	286.0	COG1674@1|root,COG1674@2|Bacteria,1MVPI@1224|Proteobacteria,42N4X@68525|delta/epsilon subdivisions,2WIPR@28221|Deltaproteobacteria,2MI69@213118|Desulfobacterales	28221|Deltaproteobacteria	D	DNA segregation ATPase, FtsK SpoIIIE family	ftsK	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
k59_102197_1	1121918.ARWE01000001_gene1548	1.13e-87	281.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	two component, sigma54 specific, transcriptional regulator, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
k59_140039_1	1200792.AKYF01000025_gene6051	1.25e-35	140.0	COG0714@1|root,COG1112@1|root,COG0714@2|Bacteria,COG1112@2|Bacteria,1TP20@1239|Firmicutes,4HDDW@91061|Bacilli,26VZZ@186822|Paenibacillaceae	91061|Bacilli	L	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_11,AAA_12,DUF2726,DUF3320,DUF4011,DUF559
k59_18350_1	706587.Desti_4230	8.12e-85	264.0	COG0683@1|root,COG0683@2|Bacteria,1MWNB@1224|Proteobacteria,42TEX@68525|delta/epsilon subdivisions,2WPG8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Receptor family ligand binding region	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
k59_162559_1	536233.CLO_2680	6.97e-24	103.0	COG0331@1|root,COG0331@2|Bacteria,1TPB7@1239|Firmicutes,247UF@186801|Clostridia,36FFG@31979|Clostridiaceae	186801|Clostridia	I	malonyl CoA-acyl carrier protein transacylase	fabD	-	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
k59_132382_1	1121406.JAEX01000011_gene2006	2.42e-41	152.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2WJ8D@28221|Deltaproteobacteria,2M9AP@213115|Desulfovibrionales	28221|Deltaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
k59_132382_2	643562.Daes_2483	1.86e-89	278.0	COG0845@1|root,COG0845@2|Bacteria,1RI9S@1224|Proteobacteria,42T1D@68525|delta/epsilon subdivisions,2X5J9@28221|Deltaproteobacteria,2MGRU@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
k59_109414_1	555779.Dthio_PD1151	9.45e-124	384.0	COG0458@1|root,COG0458@2|Bacteria,1MUDZ@1224|Proteobacteria,42MGK@68525|delta/epsilon subdivisions,2WJQH@28221|Deltaproteobacteria,2M8J7@213115|Desulfovibrionales	28221|Deltaproteobacteria	F	Belongs to the CarB family	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
k59_132389_1	439235.Dalk_4970	1.48e-19	83.6	COG0316@1|root,COG0316@2|Bacteria,1N8FK@1224|Proteobacteria,42VBF@68525|delta/epsilon subdivisions,2WR7Y@28221|Deltaproteobacteria,2MKZ6@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Belongs to the HesB IscA family	-	-	-	-	-	-	-	-	-	-	-	-	Fe-S_biosyn
k59_125051_1	1232437.KL662025_gene932	7.5e-153	440.0	COG0133@1|root,COG0133@2|Bacteria,1MUS8@1224|Proteobacteria,42MIA@68525|delta/epsilon subdivisions,2WJJA@28221|Deltaproteobacteria,2MHP8@213118|Desulfobacterales	28221|Deltaproteobacteria	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB	-	4.2.1.20	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
k59_125051_2	635013.TherJR_1603	1.73e-40	141.0	COG0135@1|root,COG0135@2|Bacteria,1V6Y0@1239|Firmicutes,24HBQ@186801|Clostridia,2623G@186807|Peptococcaceae	186801|Clostridia	E	Belongs to the TrpF family	trpF	-	5.3.1.24	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03509	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	PRAI
k59_71597_1	56780.SYN_01010	4.51e-46	166.0	COG1538@1|root,COG1538@2|Bacteria,1PTZ6@1224|Proteobacteria,42RK2@68525|delta/epsilon subdivisions,2WNMB@28221|Deltaproteobacteria,2MS0Y@213462|Syntrophobacterales	28221|Deltaproteobacteria	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
k59_223323_1	690850.Desaf_2364	9.55e-50	174.0	28HC9@1|root,2Z7P5@2|Bacteria,1R4BH@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_200557_1	1121904.ARBP01000018_gene2636	1.31e-60	199.0	COG0006@1|root,COG0006@2|Bacteria,4NG40@976|Bacteroidetes,47MAV@768503|Cytophagia	976|Bacteroidetes	E	Belongs to the peptidase M24B family	pepP	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	AMP_N,Peptidase_M24
k59_234602_1	244581.IM40_07720	2.19e-34	128.0	COG1043@1|root,COG1043@2|Bacteria,1MUHQ@1224|Proteobacteria,2TRK9@28211|Alphaproteobacteria,47ETJ@766|Rickettsiales	766|Rickettsiales	M	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxA	-	2.3.1.129	ko:K00677	ko00540,ko01100,ko01503,map00540,map01100,map01503	M00060	R04567	RC00039,RC00055	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Acetyltransf_11,Hexapep
k59_44127_1	933262.AXAM01000011_gene1756	2.67e-96	293.0	COG0674@1|root,COG0674@2|Bacteria,1MVM0@1224|Proteobacteria,42MZ0@68525|delta/epsilon subdivisions,2WJG3@28221|Deltaproteobacteria,2MJ3H@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Pyruvate:ferredoxin oxidoreductase core domain II	-	-	1.2.7.1	ko:K00169	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR_N
k59_44127_2	1121405.dsmv_1954	4.38e-87	263.0	COG1013@1|root,COG1013@2|Bacteria,1MUY9@1224|Proteobacteria,42MQY@68525|delta/epsilon subdivisions,2WJGJ@28221|Deltaproteobacteria,2MJ2R@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain	-	-	1.2.7.1,1.2.7.7	ko:K00170,ko:K00187	ko00010,ko00020,ko00280,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R07160,R08034,R08566,R08567	RC00004,RC00250,RC02742,RC02833,RC02856	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
k59_143608_1	1168065.DOK_15504	5.63e-09	61.6	COG1595@1|root,COG1595@2|Bacteria,1RI7C@1224|Proteobacteria,1S6D1@1236|Gammaproteobacteria,1J6CR@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	K	COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog	rpoE	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
k59_97613_1	1144275.COCOR_01063	9.86e-43	153.0	COG0596@1|root,COG0596@2|Bacteria,1QVBQ@1224|Proteobacteria	1224|Proteobacteria	S	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_226382_1	933262.AXAM01000025_gene3415	7.71e-142	414.0	COG0593@1|root,COG0593@2|Bacteria,1MU5H@1224|Proteobacteria,42MA0@68525|delta/epsilon subdivisions,2WJAT@28221|Deltaproteobacteria,2MHNX@213118|Desulfobacterales	28221|Deltaproteobacteria	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	-	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
k59_234604_1	335543.Sfum_3630	7.23e-60	192.0	COG0194@1|root,COG0194@2|Bacteria,1MW92@1224|Proteobacteria,42R4H@68525|delta/epsilon subdivisions,2WNAD@28221|Deltaproteobacteria,2MRZT@213462|Syntrophobacterales	28221|Deltaproteobacteria	F	Essential for recycling GMP and indirectly, cGMP	gmk	GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_kin
k59_234604_2	335543.Sfum_3631	1.2e-14	68.6	COG2052@1|root,COG2052@2|Bacteria,1N0KP@1224|Proteobacteria,42TSK@68525|delta/epsilon subdivisions,2WQHH@28221|Deltaproteobacteria,2MS3J@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Belongs to the UPF0296 family	-	-	-	ko:K09777	-	-	-	-	ko00000	-	-	-	DUF370
k59_158429_1	443143.GM18_3095	1.66e-45	165.0	COG0123@1|root,COG0123@2|Bacteria,1MU7P@1224|Proteobacteria,42MY3@68525|delta/epsilon subdivisions,2WJEF@28221|Deltaproteobacteria,43TQX@69541|Desulfuromonadales	28221|Deltaproteobacteria	BQ	Histone deacetylase domain	-	-	-	ko:K04768	-	-	-	-	ko00000	-	-	-	Hist_deacetyl
k59_241380_1	880072.Desac_2532	5.42e-110	335.0	COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,42M1X@68525|delta/epsilon subdivisions,2WJA2@28221|Deltaproteobacteria,2MQ8Y@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	Thiamine pyrophosphate enzyme, central	ilvB	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
k59_90132_1	398767.Glov_2122	2.77e-26	107.0	COG3267@1|root,COG3267@2|Bacteria,1REY9@1224|Proteobacteria,42RJB@68525|delta/epsilon subdivisions,2WN99@28221|Deltaproteobacteria,43TEB@69541|Desulfuromonadales	28221|Deltaproteobacteria	U	Pfam:Arch_ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22
k59_120080_1	1121405.dsmv_0525	6.48e-74	229.0	COG2003@1|root,COG2003@2|Bacteria,1MXZ5@1224|Proteobacteria,42PPW@68525|delta/epsilon subdivisions,2WM1S@28221|Deltaproteobacteria,2MIWE@213118|Desulfobacterales	28221|Deltaproteobacteria	L	Belongs to the UPF0758 family	radC	-	-	ko:K03630	-	-	-	-	ko00000	-	-	-	RadC
k59_21570_2	1121382.JQKG01000010_gene4646	3.09e-20	95.1	28M0D@1|root,2ZAFE@2|Bacteria,1WM8R@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Putative ATP-binding cassette	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran_2
k59_83262_1	126957.SMAR011751-PA	7.33e-27	105.0	COG0237@1|root,KOG3220@2759|Eukaryota,38DFB@33154|Opisthokonta,3BCMM@33208|Metazoa,3CYKU@33213|Bilateria,41XVB@6656|Arthropoda	33208|Metazoa	H	dephospho-CoA kinase activity. It is involved in the biological process described with coenzyme A biosynthetic process	dcakd	GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.1.24,3.4.22.68	ko:K00859,ko:K08597	ko00770,ko01100,map00770,map01100	M00120	R00130	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01002,ko04121	-	-	-	CoaE
k59_219277_1	335543.Sfum_3201	5.41e-96	296.0	COG0007@1|root,COG1587@1|root,COG0007@2|Bacteria,COG1587@2|Bacteria,1MUI0@1224|Proteobacteria,42MCB@68525|delta/epsilon subdivisions,2WIRJ@28221|Deltaproteobacteria,2MQX4@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	Belongs to the precorrin methyltransferase family	hemD	-	1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.4	ko:K02302,ko:K02303,ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03165,R03194,R03947	RC00003,RC00871,RC01012,RC01034,RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4,TP_methylase
k59_98054_1	1047013.AQSP01000134_gene1362	2.14e-80	255.0	2DBU2@1|root,2ZB3S@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_4
k59_165947_1	118163.Ple7327_3996	1.73e-87	269.0	COG2334@1|root,COG2334@2|Bacteria,1G1QD@1117|Cyanobacteria,3VHR8@52604|Pleurocapsales	1117|Cyanobacteria	S	PFAM Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
k59_106127_2	1121403.AUCV01000008_gene1543	8.82e-07	56.6	COG0438@1|root,COG0438@2|Bacteria,1R2HF@1224|Proteobacteria,43DDY@68525|delta/epsilon subdivisions,2X8JT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_6285_1	764298.STRMA_1904	0.000696	45.4	COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1U766@1239|Firmicutes,4HG3G@91061|Bacilli	91061|Bacilli	T	response regulator	rr09	-	-	ko:K07720	ko02020,map02020	M00519	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_18,Response_reg
k59_204550_1	374847.Kcr_0561	7.78e-09	58.9	COG2095@1|root,arCOG01997@2157|Archaea	2157|Archaea	U	UPF0056 membrane protein	-	-	-	ko:K05595	-	-	-	-	ko00000,ko02000	2.A.95.1	-	-	MarC
k59_219282_1	1232437.KL661988_gene227	1.17e-83	262.0	COG4591@1|root,COG4591@2|Bacteria,1R4Q2@1224|Proteobacteria,42QGA@68525|delta/epsilon subdivisions,2WJYS@28221|Deltaproteobacteria,2MI4W@213118|Desulfobacterales	28221|Deltaproteobacteria	M	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
k59_37775_1	439235.Dalk_4801	7.71e-75	234.0	COG3385@1|root,COG3385@2|Bacteria,1PMXF@1224|Proteobacteria,43B8Z@68525|delta/epsilon subdivisions,2X6NB@28221|Deltaproteobacteria,2MPI8@213118|Desulfobacterales	1224|Proteobacteria	L	PFAM transposase IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DUF4372
k59_90804_1	335543.Sfum_0121	6.92e-119	355.0	COG0459@1|root,COG0459@2|Bacteria,1MURR@1224|Proteobacteria,42M52@68525|delta/epsilon subdivisions,2WIRK@28221|Deltaproteobacteria,2MRAR@213462|Syntrophobacterales	28221|Deltaproteobacteria	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	-	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
k59_6293_1	765911.Thivi_1896	7.45e-31	122.0	COG1075@1|root,COG1075@2|Bacteria,1R5PK@1224|Proteobacteria,1RP0G@1236|Gammaproteobacteria,1WX6E@135613|Chromatiales	135613|Chromatiales	S	acetyltransferases and hydrolases with the alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
k59_29447_1	1121405.dsmv_3644	1.61e-100	326.0	COG0086@1|root,COG0086@2|Bacteria,1MU3M@1224|Proteobacteria,42NAW@68525|delta/epsilon subdivisions,2WISU@28221|Deltaproteobacteria,2MIYJ@213118|Desulfobacterales	28221|Deltaproteobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	-	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
k59_98078_1	266265.Bxe_C0332	0.000239	44.3	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,2VH4C@28216|Betaproteobacteria,1K6MA@119060|Burkholderiaceae	28216|Betaproteobacteria	I	Thiolase, C-terminal domain	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
k59_98078_2	997346.HMPREF9374_2432	2.89e-09	57.0	COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,4HAKV@91061|Bacilli,27BD9@186824|Thermoactinomycetaceae	91061|Bacilli	I	Acyl-CoA dehydrogenase, C-terminal domain	acdA	-	1.3.8.1,1.3.8.7	ko:K00248,ko:K00249	ko00071,ko00280,ko00410,ko00640,ko00650,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map00650,map01100,map01110,map01120,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01178,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00120,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
k59_52452_1	439235.Dalk_2209	1.75e-84	259.0	COG3264@1|root,COG3264@2|Bacteria,1MWSA@1224|Proteobacteria,42NUP@68525|delta/epsilon subdivisions,2WKSD@28221|Deltaproteobacteria,2MNKG@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Mechanosensitive ion channel	mscS-1	-	-	ko:K16052	-	-	-	-	ko00000,ko02000	1.A.23.4	-	-	MS_channel
k59_226923_1	63737.Npun_F1376	5.84e-95	287.0	COG0451@1|root,COG0451@2|Bacteria,1G0GJ@1117|Cyanobacteria,1HJAB@1161|Nostocales	1117|Cyanobacteria	M	PFAM NAD dependent epimerase dehydratase family	-	-	5.1.3.6	ko:K08679	ko00520,ko01100,map00520,map01100	-	R01385	RC00289	ko00000,ko00001,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
k59_241894_1	269799.Gmet_0653	4.24e-135	392.0	COG0202@1|root,COG0202@2|Bacteria,1MU75@1224|Proteobacteria,42MIX@68525|delta/epsilon subdivisions,2WJ5K@28221|Deltaproteobacteria,43TN3@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
k59_98084_1	314345.SPV1_06539	7.61e-102	311.0	COG1295@1|root,COG1295@2|Bacteria,1QICW@1224|Proteobacteria	1224|Proteobacteria	K	UPF0761 membrane protein	rbn	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
k59_226926_1	156889.Mmc1_2394	3.8e-37	145.0	COG0642@1|root,COG0745@1|root,COG0784@1|root,COG0834@1|root,COG2198@1|root,COG0745@2|Bacteria,COG0784@2|Bacteria,COG0834@2|Bacteria,COG2198@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HAMP,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_9,Response_reg,SBP_bac_3
k59_98099_1	1333998.M2A_0859	7.37e-72	225.0	COG1294@1|root,COG1294@2|Bacteria,1MURP@1224|Proteobacteria,2TU3I@28211|Alphaproteobacteria,4BR9P@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	C	Cytochrome bd terminal oxidase subunit II	cydB	-	1.10.3.14	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	Cyt_bd_oxida_II
k59_98099_2	1232437.KL662047_gene5208	5.04e-21	92.0	COG1271@1|root,COG1271@2|Bacteria,1MV60@1224|Proteobacteria,42P0J@68525|delta/epsilon subdivisions,2WJJQ@28221|Deltaproteobacteria,2MIYI@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Cytochrome bd terminal oxidase subunit I	-	-	1.10.3.14	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	Cyt_bd_oxida_I
k59_181163_1	1121405.dsmv_1659	3.43e-17	76.3	COG3197@1|root,COG3197@2|Bacteria,1P4MU@1224|Proteobacteria,432XF@68525|delta/epsilon subdivisions,2WYHY@28221|Deltaproteobacteria,2MPDK@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Cytochrome oxidase maturation protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_165963_1	1480694.DC28_09190	3.75e-128	377.0	COG0442@1|root,COG0442@2|Bacteria,2J5HF@203691|Spirochaetes	203691|Spirochaetes	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS	proS	-	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,ProRS-C_1,tRNA-synt_2b
k59_226934_1	985665.HPL003_07240	2.45e-61	201.0	COG1235@1|root,COG1235@2|Bacteria,1TQ8E@1239|Firmicutes,4HAKD@91061|Bacilli,26RZN@186822|Paenibacillaceae	91061|Bacilli	S	Metal-dependent hydrolases of the beta-lactamase superfamily I	vicX	-	3.1.26.11	ko:K00784	ko03013,map03013	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	Lactamase_B,Lactamase_B_2
k59_29473_1	1121927.GOHSU_02_02450	2.43e-07	59.7	COG0842@1|root,COG1131@1|root,COG1716@1|root,COG0842@2|Bacteria,COG1131@2|Bacteria,COG1716@2|Bacteria,2GKEU@201174|Actinobacteria,4GBVK@85026|Gordoniaceae	201174|Actinobacteria	V	Inner membrane component of T3SS, cytoplasmic domain	-	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006810,GO:0008150,GO:0015399,GO:0015405,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0030312,GO:0031224,GO:0042623,GO:0042626,GO:0043492,GO:0044424,GO:0044425,GO:0044444,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944	-	ko:K01990,ko:K21397	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane,ABC_tran,FHA
k59_165965_1	177437.HRM2_39480	1.8e-09	63.9	COG3385@1|root,COG3385@2|Bacteria,1RM2A@1224|Proteobacteria,42WE3@68525|delta/epsilon subdivisions,2X6QW@28221|Deltaproteobacteria,2MN97@213118|Desulfobacterales	28221|Deltaproteobacteria	L	Transposase DDE domain group 1	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_4
k59_75381_1	378806.STAUR_6990	1.75e-33	133.0	COG4412@1|root,COG4412@2|Bacteria,1R3SG@1224|Proteobacteria,42SZZ@68525|delta/epsilon subdivisions,2WPD0@28221|Deltaproteobacteria,2YUKS@29|Myxococcales	28221|Deltaproteobacteria	E	Fungalysin metallopeptidase (M36)	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M36,REJ
k59_44734_1	880072.Desac_1090	8.13e-52	184.0	COG0031@1|root,COG0215@1|root,COG0031@2|Bacteria,COG0215@2|Bacteria,1MUBE@1224|Proteobacteria,42M6M@68525|delta/epsilon subdivisions,2WIQM@28221|Deltaproteobacteria,2MR3Q@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	Pyridoxal-phosphate dependent enzyme	cysM	-	2.5.1.47,6.1.1.16	ko:K01738,ko:K01883,ko:K12339	ko00270,ko00920,ko00970,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map00970,map01100,map01110,map01120,map01130,map01200,map01230	M00021,M00359,M00360	R00897,R03132,R03601,R03650,R04859	RC00020,RC00055,RC00523,RC02814,RC02821,RC02876	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,PALP,tRNA-synt_1e
k59_37798_1	1283300.ATXB01000001_gene387	3.31e-76	242.0	COG1752@1|root,COG1752@2|Bacteria,1NT1Q@1224|Proteobacteria,1RP9M@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	esterase of the alpha-beta hydrolase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Patatin
k59_204607_1	96561.Dole_2972	4.31e-30	118.0	COG4783@1|root,COG4783@2|Bacteria,1MVFV@1224|Proteobacteria,42P1P@68525|delta/epsilon subdivisions,2WJ99@28221|Deltaproteobacteria,2MJA4@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48,TAT_signal,TPR_16,TPR_19
k59_204607_2	1304885.AUEY01000017_gene3728	1.61e-39	135.0	COG0219@1|root,COG0219@2|Bacteria,1RCY4@1224|Proteobacteria,42RJX@68525|delta/epsilon subdivisions,2WQNR@28221|Deltaproteobacteria,2MJWZ@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide	trmL	-	2.1.1.207	ko:K03216	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
k59_226953_1	177437.HRM2_44240	1.16e-06	48.9	COG0546@1|root,COG0546@2|Bacteria,1RDDY@1224|Proteobacteria,42T69@68525|delta/epsilon subdivisions,2WNN3@28221|Deltaproteobacteria,2MJYN@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Haloacid dehalogenase-like hydrolase	gph	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
k59_128824_1	522772.Dacet_0048	5.04e-104	312.0	COG0489@1|root,COG0489@2|Bacteria,2GEUR@200930|Deferribacteres	200930|Deferribacteres	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	-	-	-	-	-	-	-	-	-	-	-	-	ParA
k59_150823_1	351348.Maqu_0236	1.64e-113	335.0	COG2801@1|root,COG2801@2|Bacteria,1MVC8@1224|Proteobacteria,1RXYF@1236|Gammaproteobacteria,46ABE@72275|Alteromonadaceae	1236|Gammaproteobacteria	L	DDE domain	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve,rve_3
k59_83331_2	335543.Sfum_0470	4.33e-12	64.7	COG0778@1|root,COG0778@2|Bacteria,1RECN@1224|Proteobacteria,42SPP@68525|delta/epsilon subdivisions,2WPPZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM Nitroreductase	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
k59_29510_1	649638.Trad_1301	9.82e-58	194.0	COG0415@1|root,COG0415@2|Bacteria,1WM2P@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	L	DNA photolyase	-	-	4.1.99.3	ko:K01669	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_photolyase
k59_44758_1	335543.Sfum_1549	2.17e-125	395.0	COG0085@1|root,COG0085@2|Bacteria,1MUC4@1224|Proteobacteria,43DMZ@68525|delta/epsilon subdivisions,2WIW5@28221|Deltaproteobacteria,2MR0B@213462|Syntrophobacterales	28221|Deltaproteobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
k59_83336_1	228410.NE1154	2.87e-16	82.0	COG2199@1|root,COG3706@2|Bacteria,1MZV7@1224|Proteobacteria,2VUP7@28216|Betaproteobacteria,374K3@32003|Nitrosomonadales	28216|Betaproteobacteria	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	2.7.7.65	ko:K13069,ko:K21085	ko02026,map02026	-	R08057	-	ko00000,ko00001,ko01000	-	-	-	CHASE7,GGDEF,HAMP
k59_44759_1	909663.KI867150_gene4	1.11e-08	55.8	COG3462@1|root,COG3462@2|Bacteria,1Q55M@1224|Proteobacteria,42WZ8@68525|delta/epsilon subdivisions,2WSP8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Short C-terminal domain	-	-	-	ko:K08982	-	-	-	-	ko00000	-	-	-	SHOCT
k59_44759_2	1167006.UWK_02486	7.89e-08	52.8	COG0670@1|root,COG0670@2|Bacteria,1MU69@1224|Proteobacteria,42MWD@68525|delta/epsilon subdivisions,2WMG9@28221|Deltaproteobacteria,2MJCA@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Belongs to the BI1 family	ybhL	-	-	ko:K06890,ko:K19416	-	M00742	-	-	ko00000,ko00002,ko02000	1.A.14.2.1	-	-	Bax1-I
k59_29515_1	56780.SYN_02777	7.45e-81	258.0	COG0465@1|root,COG0465@2|Bacteria,1MU6J@1224|Proteobacteria,42M4Z@68525|delta/epsilon subdivisions,2WJ0D@28221|Deltaproteobacteria,2MQTC@213462|Syntrophobacterales	28221|Deltaproteobacteria	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
k59_196207_1	1121456.ATVA01000013_gene907	1.7e-19	87.8	COG0517@1|root,COG0794@1|root,COG0517@2|Bacteria,COG0794@2|Bacteria,1MUXD@1224|Proteobacteria,42M0M@68525|delta/epsilon subdivisions,2WJ4Y@28221|Deltaproteobacteria,2M802@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Belongs to the SIS family. GutQ KpsF subfamily	kpsF	-	5.3.1.13	ko:K06041	ko00540,ko01100,map00540,map01100	M00063	R01530	RC00541	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CBS,SIS
k59_150839_1	909663.KI867150_gene213	3.46e-127	388.0	COG0457@1|root,COG0457@2|Bacteria,1NNJ6@1224|Proteobacteria,42PBD@68525|delta/epsilon subdivisions,2WKWJ@28221|Deltaproteobacteria,2MRCI@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	PFAM Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2,TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8
k59_159013_2	1242864.D187_007080	1.53e-68	220.0	COG1573@1|root,COG1573@2|Bacteria,1MWX1@1224|Proteobacteria,42QXV@68525|delta/epsilon subdivisions,2WMXB@28221|Deltaproteobacteria,2YUZZ@29|Myxococcales	28221|Deltaproteobacteria	L	Uracil-DNA glycosylase	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
k59_159013_3	880072.Desac_2316	1.96e-77	246.0	COG0452@1|root,COG0452@2|Bacteria,1MVQP@1224|Proteobacteria,42NIG@68525|delta/epsilon subdivisions,2WIR1@28221|Deltaproteobacteria,2MQ4I@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	coaBC	-	4.1.1.36,6.3.2.5	ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
k59_52509_1	439235.Dalk_1445	2.71e-41	153.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2WJN5@28221|Deltaproteobacteria,2MHZ6@213118|Desulfobacterales	28221|Deltaproteobacteria	V	AcrB/AcrD/AcrF family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_169501_1	351607.Acel_0906	1.35e-15	81.3	COG0683@1|root,COG0683@2|Bacteria,2HTRQ@201174|Actinobacteria,4ETY3@85013|Frankiales	201174|Actinobacteria	E	Periplasmic binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_6
k59_25514_1	1123228.AUIH01000002_gene1440	3.31e-16	73.2	COG1925@1|root,COG1925@2|Bacteria,1N6RM@1224|Proteobacteria,1SCXX@1236|Gammaproteobacteria,1XKZ0@135619|Oceanospirillales	135619|Oceanospirillales	G	Phosphocarrier protein HPr	ptsO	-	-	ko:K08485,ko:K11189	ko02060,map02060	-	-	-	ko00000,ko00001,ko02000	4.A.2.1	-	-	PTS-HPr
k59_25514_2	1232437.KL661980_gene3707	1.38e-27	114.0	COG1080@1|root,COG1080@2|Bacteria,1MUT8@1224|Proteobacteria,42P77@68525|delta/epsilon subdivisions,2WK7E@28221|Deltaproteobacteria,2MIQB@213118|Desulfobacterales	28221|Deltaproteobacteria	G	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)	ptsI	-	2.7.3.9	ko:K08483	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	8.A.7	-	-	PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C
k59_162115_1	926566.Terro_1591	1.49e-15	81.3	COG1414@1|root,COG1414@2|Bacteria,3Y4JW@57723|Acidobacteria,2JKV2@204432|Acidobacteriia	204432|Acidobacteriia	K	TIGRFAM beta-ketoadipate pathway transcriptional regulators, PcaR PcaU PobR family	-	-	-	ko:K02624	-	-	-	-	ko00000,ko03000	-	-	-	HTH_IclR,IclR
k59_207736_1	397945.Aave_0072	7.48e-11	65.1	COG2241@1|root,COG2242@1|root,COG2241@2|Bacteria,COG2242@2|Bacteria,1MVJX@1224|Proteobacteria,2VME3@28216|Betaproteobacteria,4ACX3@80864|Comamonadaceae	28216|Betaproteobacteria	H	PFAM Uroporphyrin-III C tetrapyrrole (Corrin Porphyrin) methyltransferase	cobL	-	2.1.1.132	ko:K00595	ko00860,ko01100,map00860,map01100	-	R05149	RC00003,RC01279	ko00000,ko00001,ko01000	-	-	-	Methyltransf_31,PCMT,TP_methylase
k59_207736_2	1125863.JAFN01000001_gene2366	2.86e-86	265.0	COG2875@1|root,COG2875@2|Bacteria,1MVYY@1224|Proteobacteria,42P88@68525|delta/epsilon subdivisions,2WMR1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	PFAM Uroporphyrin-III C tetrapyrrole (Corrin Porphyrin) methyltransferase	cbiF	-	2.1.1.133,2.1.1.271	ko:K05936	ko00860,ko01100,map00860,map01100	-	R05181,R05810	RC00003,RC01294,RC02049	ko00000,ko00001,ko01000	-	-	-	CbiG_C,CbiG_N,TP_methylase
k59_17841_1	573370.DMR_28530	1.32e-12	70.1	COG3149@1|root,COG3149@2|Bacteria,1NEZ3@1224|Proteobacteria,42WMP@68525|delta/epsilon subdivisions,2WSE1@28221|Deltaproteobacteria,2MDVY@213115|Desulfovibrionales	28221|Deltaproteobacteria	U	Type II secretion system (T2SS), protein M	-	-	-	ko:K02462	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSM
k59_185083_1	1499967.BAYZ01000164_gene6661	1.23e-85	282.0	COG0642@1|root,COG5002@1|root,COG0642@2|Bacteria,COG5002@2|Bacteria,2NS5N@2323|unclassified Bacteria	2|Bacteria	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HAMP,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_9,PilJ,Response_reg,dCache_1
k59_230269_1	1173022.Cri9333_4542	3.08e-47	165.0	COG0675@1|root,COG0675@2|Bacteria,1G2I1@1117|Cyanobacteria,1H9DE@1150|Oscillatoriales	1117|Cyanobacteria	L	COG0675 Transposase and inactivated derivatives	-	-	-	ko:K07496	-	-	-	-	ko00000	-	-	-	OrfB_IS605,OrfB_Zn_ribbon
k59_48234_1	439235.Dalk_2889	1.03e-29	108.0	COG0776@1|root,COG0776@2|Bacteria,1MZ5B@1224|Proteobacteria,42VDU@68525|delta/epsilon subdivisions,2WQZ5@28221|Deltaproteobacteria,2MKK3@213118|Desulfobacterales	28221|Deltaproteobacteria	L	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions	-	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
k59_48234_2	439235.Dalk_2743	1.42e-27	103.0	COG1734@1|root,COG1734@2|Bacteria,1RD08@1224|Proteobacteria,42RVK@68525|delta/epsilon subdivisions,2WNNA@28221|Deltaproteobacteria,2MJSM@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters	dksA	-	-	ko:K06204	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000,ko03009,ko03021	-	-	-	zf-dskA_traR
k59_63562_1	1323663.AROI01000022_gene840	1.57e-23	101.0	COG0664@1|root,COG0664@2|Bacteria,1R5P7@1224|Proteobacteria,1S6X3@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases	dnr	-	-	ko:K21563	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
k59_63562_2	439235.Dalk_3152	5.1e-61	200.0	COG1912@1|root,COG1912@2|Bacteria,1MV99@1224|Proteobacteria,42SHG@68525|delta/epsilon subdivisions,2WP1D@28221|Deltaproteobacteria,2MJYI@213118|Desulfobacterales	28221|Deltaproteobacteria	S	S-adenosyl-l-methionine hydroxide adenosyltransferase	-	-	-	ko:K22205	-	-	-	-	ko00000,ko01000	-	-	-	SAM_adeno_trans
k59_63562_3	1121468.AUBR01000001_gene572	5.98e-104	314.0	COG2008@1|root,COG2008@2|Bacteria,1TPZI@1239|Firmicutes,25J0X@186801|Clostridia,42F6Z@68295|Thermoanaerobacterales	186801|Clostridia	E	aromatic amino acid beta-eliminating lyase threonine aldolase	ltaA	-	4.1.2.48	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	-	R00751,R06171	RC00312,RC00372	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
k59_116279_1	1121405.dsmv_0564	8.11e-78	260.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1MXBU@1224|Proteobacteria,42M59@68525|delta/epsilon subdivisions,2WIUK@28221|Deltaproteobacteria,2MICN@213118|Desulfobacterales	28221|Deltaproteobacteria	G	Pyruvate phosphate dikinase, PEP	-	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PPDK_N
k59_162117_1	574087.Acear_1671	8.39e-12	68.9	COG0552@1|root,COG0552@2|Bacteria,1TPRI@1239|Firmicutes,247JD@186801|Clostridia,3WAG4@53433|Halanaerobiales	186801|Clostridia	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)	ftsY	-	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
k59_162117_2	439235.Dalk_0785	1.09e-20	90.9	COG1196@1|root,COG1196@2|Bacteria,1MUAQ@1224|Proteobacteria,42MN9@68525|delta/epsilon subdivisions,2WJZF@28221|Deltaproteobacteria,2MHU0@213118|Desulfobacterales	28221|Deltaproteobacteria	D	Required for chromosome condensation and partitioning	smc	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
k59_17852_1	880072.Desac_1854	2.66e-128	375.0	COG1219@1|root,COG1219@2|Bacteria,1MVQK@1224|Proteobacteria	2|Bacteria	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	-	-	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small
k59_177233_1	335543.Sfum_0020	7.38e-83	269.0	COG1067@1|root,COG1067@2|Bacteria,1MWGB@1224|Proteobacteria,42NJD@68525|delta/epsilon subdivisions,2WJFK@28221|Deltaproteobacteria,2MQ92@213462|Syntrophobacterales	28221|Deltaproteobacteria	O	Belongs to the peptidase S16 family	-	-	3.4.21.53	ko:K01338,ko:K04076	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA_32,Lon_C
k59_154663_1	42256.RradSPS_1697	5.33e-17	86.7	COG2217@1|root,COG2217@2|Bacteria,2GIRF@201174|Actinobacteria,4CPA7@84995|Rubrobacteria	84995|Rubrobacteria	P	heavy metal translocating P-type ATPase	-	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
k59_230281_1	1121459.AQXE01000008_gene792	1.15e-06	56.6	COG2181@1|root,COG2181@2|Bacteria,1R48S@1224|Proteobacteria,42MZU@68525|delta/epsilon subdivisions,2WKKU@28221|Deltaproteobacteria,2M7X4@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	PFAM Nitrate reductase gamma subunit	dsrM	-	1.7.5.1	ko:K00374	ko00910,ko01120,ko02020,map00910,map01120,map02020	M00529,M00530	R00798,R01106,R09497	RC02812	ko00000,ko00001,ko00002,ko01000	5.A.3.1	-	-	Nitrate_red_gam
k59_56068_1	96561.Dole_1556	1.11e-48	170.0	COG1053@1|root,COG1053@2|Bacteria,1MU5M@1224|Proteobacteria,42M81@68525|delta/epsilon subdivisions,2WIJ5@28221|Deltaproteobacteria,2MHSR@213118|Desulfobacterales	28221|Deltaproteobacteria	C	TIGRFAM succinate dehydrogenase or fumarate reductase, flavoprotein subunit	frdA	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
k59_108833_1	1121405.dsmv_0146	4.04e-52	182.0	COG0484@1|root,COG0484@2|Bacteria,1R72H@1224|Proteobacteria,42NCE@68525|delta/epsilon subdivisions,2WKDN@28221|Deltaproteobacteria,2MKP5@213118|Desulfobacterales	28221|Deltaproteobacteria	O	Class III cytochrome C family	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_CIII
k59_162129_1	335543.Sfum_0006	1.47e-87	270.0	COG0517@1|root,COG0794@1|root,COG0517@2|Bacteria,COG0794@2|Bacteria,1MUXD@1224|Proteobacteria,42M0M@68525|delta/epsilon subdivisions,2WJ4Y@28221|Deltaproteobacteria,2MQCV@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	Belongs to the SIS family. GutQ KpsF subfamily	kpsF	-	5.3.1.13	ko:K06041	ko00540,ko01100,map00540,map01100	M00063	R01530	RC00541	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CBS,SIS
k59_33097_1	545264.KB898750_gene249	5.8e-60	203.0	COG0188@1|root,COG0188@2|Bacteria,1MURI@1224|Proteobacteria,1RMTC@1236|Gammaproteobacteria,1WWE3@135613|Chromatiales	135613|Chromatiales	L	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule	parC	-	-	ko:K02621	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
k59_56074_1	1121405.dsmv_3562	4.23e-85	258.0	COG0289@1|root,COG0289@2|Bacteria,1QB39@1224|Proteobacteria,42NRC@68525|delta/epsilon subdivisions,2WJGM@28221|Deltaproteobacteria,2MJ2I@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Belongs to the DapB family	-	-	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	-	DapB_C,DapB_N
k59_25529_1	1391646.AVSU01000102_gene628	5.71e-28	112.0	COG0639@1|root,COG0639@2|Bacteria,1UYXB@1239|Firmicutes,24D3D@186801|Clostridia,25RX0@186804|Peptostreptococcaceae	186801|Clostridia	T	Calcineurin-like phosphoesterase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos_2
k59_185105_1	1121441.AUCX01000012_gene3309	5.53e-52	176.0	COG0805@1|root,COG0805@2|Bacteria,1MVAY@1224|Proteobacteria,42MM7@68525|delta/epsilon subdivisions,2WKJW@28221|Deltaproteobacteria,2M9RT@213115|Desulfovibrionales	28221|Deltaproteobacteria	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides	tatC	-	-	ko:K03118	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	TatC
k59_93813_1	203122.Sde_2346	1.19e-45	167.0	COG3547@1|root,COG3547@2|Bacteria,1NGR7@1224|Proteobacteria,1RMF9@1236|Gammaproteobacteria,464W8@72275|Alteromonadaceae	1236|Gammaproteobacteria	L	COG3547 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_10469_2	479434.Sthe_0126	4.32e-10	63.9	COG2515@1|root,COG2515@2|Bacteria,2G6PX@200795|Chloroflexi,27YZ5@189775|Thermomicrobia	189775|Thermomicrobia	E	Pyridoxal-phosphate dependent enzyme	-	-	4.4.1.15	ko:K05396	ko00270,map00270	-	R01874	RC00382	ko00000,ko00001,ko01000	-	-	-	PALP
k59_101674_1	479434.Sthe_2616	7.87e-61	198.0	COG1177@1|root,COG1177@2|Bacteria,2G6DH@200795|Chloroflexi	2|Bacteria	E	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02053	ko02024,map02024	M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11	-	-	BPD_transp_1
k59_230297_1	335541.Swol_1899	3.8e-38	143.0	COG3934@1|root,COG3934@2|Bacteria,1UEWM@1239|Firmicutes,24AQC@186801|Clostridia,42KI0@68298|Syntrophomonadaceae	186801|Clostridia	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	-	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	Cellulase,Glyco_hydro_42M
k59_78811_1	742159.HMPREF0004_0306	6.83e-14	72.8	COG1215@1|root,COG1215@2|Bacteria,1QTWU@1224|Proteobacteria,2WGWG@28216|Betaproteobacteria,3T9IV@506|Alcaligenaceae	28216|Betaproteobacteria	M	Glycosyl transferase family 2	-	-	-	ko:K20534	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.2.1.9	GT2	-	Glycos_transf_2
k59_48259_1	479434.Sthe_1720	9.43e-98	298.0	COG0427@1|root,COG0427@2|Bacteria,2G60V@200795|Chloroflexi	200795|Chloroflexi	C	PFAM Acetyl-CoA hydrolase transferase	-	-	3.1.2.1	ko:K01067	ko00620,map00620	-	R00227	RC00004,RC00012	ko00000,ko00001,ko01000	-	-	-	AcetylCoA_hyd_C,AcetylCoA_hydro
k59_48259_2	484770.UFO1_4601	3.34e-114	335.0	COG1024@1|root,COG1024@2|Bacteria,1V0K6@1239|Firmicutes,4H295@909932|Negativicutes	909932|Negativicutes	I	Enoyl-CoA hydratase/isomerase	-	-	4.1.1.41	ko:K11264	ko00640,map00640	-	R00923	RC00097	ko00000,ko00001,ko01000	-	-	-	ECH_1
k59_108846_1	96561.Dole_2566	1.93e-59	198.0	COG1032@1|root,COG1032@2|Bacteria,1MUMS@1224|Proteobacteria,42QFG@68525|delta/epsilon subdivisions,2WK91@28221|Deltaproteobacteria,2MK0R@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM Radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
k59_223270_1	335543.Sfum_3479	2.89e-58	206.0	COG1197@1|root,COG1197@2|Bacteria,1MUXG@1224|Proteobacteria,42N8X@68525|delta/epsilon subdivisions,2WIVR@28221|Deltaproteobacteria,2MQ8P@213462|Syntrophobacterales	28221|Deltaproteobacteria	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
k59_170052_1	991905.SL003B_2493	4.19e-95	285.0	COG1638@1|root,COG1638@2|Bacteria,1MWAM@1224|Proteobacteria,2TTT8@28211|Alphaproteobacteria,4BRHF@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	G	Bacterial extracellular solute-binding protein, family 7	-	-	-	-	-	-	-	-	-	-	-	-	DctP
k59_215444_1	428125.CLOLEP_01726	7.36e-08	59.3	COG1453@1|root,COG1453@2|Bacteria,1TPBG@1239|Firmicutes,2497N@186801|Clostridia,3WGTV@541000|Ruminococcaceae	186801|Clostridia	S	4Fe-4S dicluster domain	-	-	-	ko:K07079	-	-	-	-	ko00000	-	-	-	Aldo_ket_red,Fer4_17
k59_102124_1	323261.Noc_1320	2.56e-94	295.0	COG1657@1|root,COG1657@2|Bacteria,1MUIP@1224|Proteobacteria,1S118@1236|Gammaproteobacteria,1X0F2@135613|Chromatiales	135613|Chromatiales	I	Squalene-hopene cyclase N-terminal domain	-	-	4.2.1.129,5.4.99.17	ko:K06045	ko00909,ko01110,map00909,map01110	-	R07322,R07323	RC01850,RC01851	ko00000,ko00001,ko01000	-	-	-	SQHop_cyclase_C,SQHop_cyclase_N
k59_139961_1	644282.Deba_0864	1.16e-46	164.0	COG1215@1|root,COG1215@2|Bacteria,1MWH9@1224|Proteobacteria,42PX0@68525|delta/epsilon subdivisions,2WJUG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	COG0463 Glycosyltransferases involved in cell wall biogenesis	-	-	2.4.1.266	ko:K13693	-	-	-	-	ko00000,ko01000,ko01003	-	GT81	-	-
k59_155182_1	767817.Desgi_1785	4.75e-89	281.0	COG0365@1|root,COG0365@2|Bacteria,1TQTI@1239|Firmicutes,24DPN@186801|Clostridia,260G2@186807|Peptococcaceae	186801|Clostridia	I	TIGRFAM Acetoacetyl-CoA synthase	-	-	6.2.1.16	ko:K01907	ko00280,ko00650,map00280,map00650	-	R01357	RC00004,RC00014	ko00000,ko00001,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
k59_109309_1	1502851.FG93_00182	1.62e-75	254.0	COG0642@1|root,COG2203@1|root,COG5002@1|root,COG2203@2|Bacteria,COG2205@2|Bacteria,COG5002@2|Bacteria,1NRP8@1224|Proteobacteria,2TX3Q@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	Histidine kinase-like ATPases	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HAMP,HATPase_c,HisKA,Hpt,Response_reg,dCache_1
k59_162516_1	436308.Nmar_1794	3.8e-61	213.0	COG1933@1|root,arCOG04447@2157|Archaea,41SYW@651137|Thaumarchaeota	651137|Thaumarchaeota	L	Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase	polC	-	2.7.7.7	ko:K02322	ko00230,ko00240,ko01100,ko03030,map00230,map00240,map01100,map03030	M00264	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032	-	-	-	PolC_DP2
k59_41160_2	118161.KB235922_gene2524	2.55e-14	77.4	COG0739@1|root,COG0739@2|Bacteria,1G1GS@1117|Cyanobacteria,3VJK5@52604|Pleurocapsales	1117|Cyanobacteria	M	PFAM Peptidase family M23	nlpD	-	-	-	-	-	-	-	-	-	-	-	LysM,Peptidase_M23
k59_223271_1	237368.SCABRO_02054	2.73e-40	149.0	COG0560@1|root,COG0560@2|Bacteria,2J2N0@203682|Planctomycetes	203682|Planctomycetes	ET	ACT domain	-	-	3.1.3.3	ko:K01079	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R00582	RC00017	ko00000,ko00001,ko00002,ko01000,ko01009	-	-	-	ACT_6,HAD
k59_18286_1	500153.JOEK01000002_gene323	3.64e-41	147.0	COG4977@1|root,COG4977@2|Bacteria,2GIRA@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain	-	-	-	ko:K13633	-	-	-	-	ko00000,ko03000	-	-	-	DJ-1_PfpI,HTH_18
k59_200456_1	1282362.AEAC466_03765	3.2e-15	76.6	COG0300@1|root,COG0300@2|Bacteria,1MWNZ@1224|Proteobacteria,2VEWB@28211|Alphaproteobacteria,2KIII@204458|Caulobacterales	204458|Caulobacterales	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
k59_116791_1	706587.Desti_2925	1.75e-74	233.0	COG1235@1|root,COG1235@2|Bacteria,1MVJH@1224|Proteobacteria,42W9U@68525|delta/epsilon subdivisions,2WRHS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Beta-lactamase superfamily domain	-	-	3.1.4.55	ko:K06167	ko00440,map00440	-	R10205	RC00296	ko00000,ko00001,ko01000	-	-	-	Lactamase_B_2
k59_25910_1	933262.AXAM01000113_gene2117	1.56e-103	320.0	COG1328@1|root,COG1328@2|Bacteria,1MWMS@1224|Proteobacteria,42M8V@68525|delta/epsilon subdivisions,2WJ7S@28221|Deltaproteobacteria,2MHTW@213118|Desulfobacterales	28221|Deltaproteobacteria	F	anaerobic ribonucleoside-triphosphate reductase	nrdD	-	1.1.98.6	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R11633,R11634,R11635,R11636	RC00613	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-cone,NRDD
k59_162519_2	1469245.JFBG01000052_gene2168	5.4e-62	197.0	COG0411@1|root,COG0411@2|Bacteria,1MUTY@1224|Proteobacteria,1RQU2@1236|Gammaproteobacteria,1X2CD@135613|Chromatiales	135613|Chromatiales	E	Branched-chain amino acid ATP-binding cassette transporter	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
k59_238319_1	10224.XP_006825930.1	6.01e-47	171.0	KOG1075@1|root,KOG1075@2759|Eukaryota,39Y6T@33154|Opisthokonta,3BEGN@33208|Metazoa,3CZ7K@33213|Bilateria	33208|Metazoa	G	positive regulation of TOR signaling	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos_2,RVT_1
k59_109319_2	177439.DP0110	5.3e-32	122.0	COG3167@1|root,COG3167@2|Bacteria,1RBGW@1224|Proteobacteria,42S1V@68525|delta/epsilon subdivisions,2WNDR@28221|Deltaproteobacteria,2MJVB@213118|Desulfobacterales	28221|Deltaproteobacteria	NU	PFAM Pilus assembly protein PilO	pilO	-	-	ko:K02664	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilO
k59_71504_1	555779.Dthio_PD3138	6.89e-23	90.9	COG0776@1|root,COG0776@2|Bacteria,1MZ7M@1224|Proteobacteria,42TVD@68525|delta/epsilon subdivisions,2WQPX@28221|Deltaproteobacteria,2MCIY@213115|Desulfovibrionales	28221|Deltaproteobacteria	L	Belongs to the bacterial histone-like protein family	ihfB	-	-	ko:K05788	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
k59_25911_1	1265505.ATUG01000003_gene114	2.4e-111	326.0	COG0752@1|root,COG0752@2|Bacteria,1MVCJ@1224|Proteobacteria,42MNQ@68525|delta/epsilon subdivisions,2WJJW@28221|Deltaproteobacteria,2MI7B@213118|Desulfobacterales	28221|Deltaproteobacteria	J	PFAM glycyl-tRNA synthetase alpha subunit	glyQ	-	6.1.1.14	ko:K01878	ko00970,map00970	M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iAF987.Gmet_2942	tRNA-synt_2e
k59_102139_1	1120979.ATVB01000003_gene441	2.34e-07	53.9	COG0196@1|root,COG0196@2|Bacteria,2GKQF@201174|Actinobacteria,4CYXT@85004|Bifidobacteriales	201174|Actinobacteria	H	riboflavin kinase	ribF	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0006139,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006771,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008531,GO:0009058,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009124,GO:0009156,GO:0009161,GO:0009165,GO:0009231,GO:0009259,GO:0009260,GO:0009398,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019866,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0034641,GO:0034654,GO:0042364,GO:0042726,GO:0042727,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046390,GO:0046444,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
k59_170072_1	1121405.dsmv_2795	1.74e-54	184.0	COG2223@1|root,COG2223@2|Bacteria,1MWC7@1224|Proteobacteria,42P53@68525|delta/epsilon subdivisions,2WJ2U@28221|Deltaproteobacteria,2MIZU@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Major Facilitator Superfamily	-	-	-	ko:K08177	-	-	-	-	ko00000,ko02000	2.A.1.11	-	-	MFS_1
k59_124997_1	983548.Krodi_0264	3.49e-28	113.0	COG3367@1|root,COG3367@2|Bacteria,4NGXN@976|Bacteroidetes,1I06G@117743|Flavobacteriia,37FQI@326319|Dokdonia	976|Bacteroidetes	S	Domain of unknown function (DUF1611_N) Rossmann-like domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF1611,DUF1611_N
k59_124997_2	1121405.dsmv_2608	3.72e-14	71.2	COG0498@1|root,COG0498@2|Bacteria	2|Bacteria	E	threonine synthase activity	-	-	2.5.1.76,4.2.3.1	ko:K01733,ko:K15527	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetyltransf_1,PALP
k59_230929_1	1265505.ATUG01000001_gene3091	2.23e-81	256.0	COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,42MFH@68525|delta/epsilon subdivisions,2WIRW@28221|Deltaproteobacteria,2MMJY@213118|Desulfobacterales	28221|Deltaproteobacteria	KT	Sigma-54 interaction domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,PAS,PAS_9,Sigma54_activat
k59_41174_1	660470.Theba_0066	2.01e-18	83.2	COG1410@1|root,COG1410@2|Bacteria	2|Bacteria	E	methionine synthase	-	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	Met_synt_B12
k59_223280_1	941449.dsx2_1488	2.14e-45	164.0	COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,42N7Y@68525|delta/epsilon subdivisions,2WIX7@28221|Deltaproteobacteria,2M7ZC@213115|Desulfovibrionales	28221|Deltaproteobacteria	KT	sigma54 specific transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,PAS,PAS_4,PAS_8,Sigma54_activat
k59_56571_1	706587.Desti_2549	3.56e-28	118.0	COG0348@1|root,COG1143@1|root,COG1149@1|root,COG0348@2|Bacteria,COG1143@2|Bacteria,COG1149@2|Bacteria,1QUNB@1224|Proteobacteria,43BMZ@68525|delta/epsilon subdivisions,2X701@28221|Deltaproteobacteria,2MQGZ@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	PFAM 4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_4,Fer4_5
k59_230932_1	463191.SSEG_01719	6.48e-19	91.3	COG0683@1|root,COG0683@2|Bacteria,2GM00@201174|Actinobacteria	201174|Actinobacteria	E	PFAM Extracellular ligand-binding receptor	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
k59_208310_1	1121405.dsmv_1129	1.22e-72	244.0	COG3852@1|root,COG4191@1|root,COG3852@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42M1R@68525|delta/epsilon subdivisions,2X734@28221|Deltaproteobacteria,2MIC0@213118|Desulfobacterales	28221|Deltaproteobacteria	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
k59_59364_1	641107.CDLVIII_5310	1.46e-41	154.0	COG4467@1|root,COG4467@2|Bacteria,1VK8R@1239|Firmicutes,24979@186801|Clostridia	186801|Clostridia	S	Transposase IS66 family	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS66
k59_149415_1	1229780.BN381_40079	3.05e-64	207.0	COG2135@1|root,COG2135@2|Bacteria,2GKY8@201174|Actinobacteria,3UWQB@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	SOS response associated peptidase (SRAP)	-	-	-	-	-	-	-	-	-	-	-	-	SRAP
k59_157618_1	439235.Dalk_1072	2.43e-44	163.0	COG0784@1|root,COG2203@1|root,COG2204@1|root,COG4191@1|root,COG0784@2|Bacteria,COG2203@2|Bacteria,COG2204@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MC4@68525|delta/epsilon subdivisions,2WIZU@28221|Deltaproteobacteria,2MJ2F@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	ABC_sub_bind,GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
k59_59367_1	1121405.dsmv_0591	1.3e-20	90.5	COG0370@1|root,COG0370@2|Bacteria,1QWMI@1224|Proteobacteria,43BSF@68525|delta/epsilon subdivisions,2X739@28221|Deltaproteobacteria,2MI8F@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Transporter of a GTP-driven Fe(2 ) uptake system	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_59367_2	889378.Spiaf_2779	3.14e-41	151.0	COG0455@1|root,COG0455@2|Bacteria,2J5K5@203691|Spirochaetes	203691|Spirochaetes	D	ATP-binding protein	ylxH-2	-	-	ko:K04562	-	-	-	-	ko00000,ko02035	-	-	-	CbiA,ParA
k59_164749_1	946483.Cenrod_2139	2.13e-51	186.0	COG0643@1|root,COG0745@1|root,COG2198@1|root,COG0643@2|Bacteria,COG0745@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,2VJSZ@28216|Betaproteobacteria,4ACMW@80864|Comamonadaceae	28216|Betaproteobacteria	T	Two component signalling adaptor domain	-	GO:0003674,GO:0005488,GO:0005515,GO:0019904	2.7.13.3	ko:K03407,ko:K13490	ko02020,ko02025,ko02030,map02020,map02025,map02030	M00506,M00509	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,HATPase_c,Hpt,Response_reg
k59_188324_1	1121403.AUCV01000008_gene1588	1.13e-57	183.0	COG1329@1|root,COG1329@2|Bacteria,1MWI2@1224|Proteobacteria,42RXS@68525|delta/epsilon subdivisions,2WNA0@28221|Deltaproteobacteria,2MJTK@213118|Desulfobacterales	28221|Deltaproteobacteria	K	PFAM transcription factor CarD	-	-	-	ko:K07736	-	-	-	-	ko00000,ko03000	-	-	-	CarD_CdnL_TRCF
k59_142697_1	269799.Gmet_2785	2.82e-59	197.0	COG2403@1|root,COG2403@2|Bacteria,1MV4C@1224|Proteobacteria,42NE0@68525|delta/epsilon subdivisions,2WJ94@28221|Deltaproteobacteria,43TJC@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	cyclic 2,3-diphosphoglycerate synthetase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_66215_2	264732.Moth_0836	1.63e-07	54.3	COG4839@1|root,COG4839@2|Bacteria	2|Bacteria	D	cell division protein FtsL	ftsL	-	-	-	-	-	-	-	-	-	-	-	DivIC
k59_51051_1	398767.Glov_1376	2.19e-37	145.0	COG5000@1|root,COG5000@2|Bacteria,1MWKZ@1224|Proteobacteria,42MCN@68525|delta/epsilon subdivisions,2WIYA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	histidine kinase HAMP region domain protein	ntrY	-	2.7.13.3	ko:K13598	ko02020,map02020	M00498	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4
k59_51051_2	439235.Dalk_0920	1.61e-64	204.0	29GM5@1|root,303IT@2|Bacteria,1RG3T@1224|Proteobacteria,42RUX@68525|delta/epsilon subdivisions,2WNMJ@28221|Deltaproteobacteria,2MJY1@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4390)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4390
k59_104622_1	335543.Sfum_1337	3.96e-65	221.0	COG0745@1|root,COG4191@1|root,COG0745@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MC4@68525|delta/epsilon subdivisions,2WIU5@28221|Deltaproteobacteria,2MQZQ@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
k59_74166_1	1265505.ATUG01000002_gene1748	8.58e-101	314.0	COG0404@1|root,COG0665@1|root,COG0404@2|Bacteria,COG0665@2|Bacteria,1MUXJ@1224|Proteobacteria,43AZ4@68525|delta/epsilon subdivisions,2X6DG@28221|Deltaproteobacteria,2MPHR@213118|Desulfobacterales	1224|Proteobacteria	E	FAD dependent oxidoreductase central domain	dmgdh2	-	1.5.8.4	ko:K00315	ko00260,ko01100,map00260,map01100	-	R01565	RC00181	ko00000,ko00001,ko01000	-	-	-	DAO,FAO_M,GCV_T,GCV_T_C
k59_119263_1	335543.Sfum_1699	4.88e-57	185.0	COG0250@1|root,COG0250@2|Bacteria,1QTE5@1224|Proteobacteria,42QT0@68525|delta/epsilon subdivisions,2WN4B@28221|Deltaproteobacteria,2MS5A@213462|Syntrophobacterales	28221|Deltaproteobacteria	K	antitermination protein NusG	-	-	-	ko:K05785	-	-	-	-	ko00000,ko03000	-	-	-	NusG
k59_172703_1	933262.AXAM01000020_gene23	7.63e-22	97.8	COG0342@1|root,COG0342@2|Bacteria,1MV5U@1224|Proteobacteria,42M6V@68525|delta/epsilon subdivisions,2WJCI@28221|Deltaproteobacteria,2MHS8@213118|Desulfobacterales	28221|Deltaproteobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
k59_164759_1	879212.DespoDRAFT_03566	3.28e-75	245.0	COG4467@1|root,COG4467@2|Bacteria,1PPMF@1224|Proteobacteria	1224|Proteobacteria	S	Involved in initiation control of chromosome replication	-	-	-	ko:K07484	-	-	-	-	ko00000	-	-	-	DDE_Tnp_IS66
k59_135671_1	118168.MC7420_3125	5.58e-42	148.0	COG3457@1|root,COG3457@2|Bacteria,1G485@1117|Cyanobacteria,1HA6G@1150|Oscillatoriales	1117|Cyanobacteria	E	Alanine racemase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Ala_racemase_N
k59_158098_1	1191523.MROS_0489	1.03e-16	77.8	COG0013@1|root,COG0013@2|Bacteria	2|Bacteria	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
k59_188767_2	1232437.KL662022_gene857	5.86e-46	156.0	COG1149@1|root,COG1149@2|Bacteria,1NCD9@1224|Proteobacteria,42PHV@68525|delta/epsilon subdivisions,2WKDZ@28221|Deltaproteobacteria,2MIUE@213118|Desulfobacterales	28221|Deltaproteobacteria	C	CobQ CobB MinD ParA nucleotide binding domain	-	-	-	-	-	-	-	-	-	-	-	-	CbiA,Fer4
k59_158099_1	1121405.dsmv_2870	3.15e-64	213.0	COG0728@1|root,COG0728@2|Bacteria,1MUH0@1224|Proteobacteria,42M28@68525|delta/epsilon subdivisions,2WJPF@28221|Deltaproteobacteria,2MHXP@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane	murJ	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
k59_149807_1	1121405.dsmv_3464	7.52e-31	129.0	COG0457@1|root,COG0457@2|Bacteria,1MYB8@1224|Proteobacteria,42P5H@68525|delta/epsilon subdivisions,2WKAU@28221|Deltaproteobacteria,2MIEU@213118|Desulfobacterales	28221|Deltaproteobacteria	G	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_14,TPR_16,TPR_19,TPR_2,TPR_4,TPR_6,TPR_7,TPR_8
k59_234296_1	335543.Sfum_0185	1.28e-82	255.0	COG0330@1|root,COG0330@2|Bacteria,1MV7R@1224|Proteobacteria,42N2V@68525|delta/epsilon subdivisions,2WIPS@28221|Deltaproteobacteria,2MRVG@213462|Syntrophobacterales	28221|Deltaproteobacteria	O	HflC and HflK could regulate a protease	hflC	-	-	ko:K04087	-	M00742	-	-	ko00000,ko00002,ko01000	-	-	-	Band_7
k59_211411_1	335543.Sfum_0854	5.85e-100	312.0	COG3290@1|root,COG3852@1|root,COG3290@2|Bacteria,COG3852@2|Bacteria,1MVN6@1224|Proteobacteria,43BPS@68525|delta/epsilon subdivisions,2X710@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Signal transduction histidine kinase, nitrogen specific	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
k59_211411_2	1408428.JNJP01000067_gene1714	1.26e-16	80.5	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,2M8CJ@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	Two component, sigma54 specific, transcriptional regulator, Fis family	-	-	-	ko:K02481	-	-	-	-	ko00000,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
k59_66613_1	1121448.DGI_3094	1.11e-23	109.0	COG2951@1|root,COG2951@2|Bacteria,1MUZ3@1224|Proteobacteria,42QGE@68525|delta/epsilon subdivisions,2X5RP@28221|Deltaproteobacteria,2M9UY@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Peptidoglycan-binding domain 1 protein	-	-	-	ko:K08305	-	-	-	-	ko00000,ko01000,ko01011	-	GH103	-	PG_binding_1,SLT_2
k59_135679_1	224719.Abm4_0510	1.27e-33	130.0	COG1964@1|root,arCOG00933@2157|Archaea,2XTMK@28890|Euryarchaeota,23NK2@183925|Methanobacteria	183925|Methanobacteria	S	4Fe-4S single cluster domain	-	-	-	ko:K06937	-	-	-	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
k59_36900_1	1121403.AUCV01000043_gene106	8.9e-48	172.0	COG0204@1|root,COG1647@1|root,COG0204@2|Bacteria,COG1647@2|Bacteria,1MVZP@1224|Proteobacteria,42NBK@68525|delta/epsilon subdivisions,2WIUP@28221|Deltaproteobacteria,2MHMP@213118|Desulfobacterales	28221|Deltaproteobacteria	I	Phosphate acyltransferases	-	-	3.1.1.1	ko:K03928	-	-	-	-	ko00000,ko01000	-	-	-	Acyltransferase,Hydrolase_4
k59_36901_1	404380.Gbem_1114	6.86e-39	147.0	COG0457@1|root,COG0457@2|Bacteria,1NNJ6@1224|Proteobacteria,42PBD@68525|delta/epsilon subdivisions,2WKWJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2,TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8
k59_135686_1	485915.Dret_0659	1.04e-05	54.3	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42N0F@68525|delta/epsilon subdivisions,2WJAE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	NT	PFAM chemotaxis sensory transducer	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CZB,HAMP,MCPsignal
k59_82394_1	1232410.KI421413_gene672	3.44e-66	228.0	COG0072@1|root,COG0072@2|Bacteria,1MWKS@1224|Proteobacteria,42M1G@68525|delta/epsilon subdivisions,2WJ7V@28221|Deltaproteobacteria,43TCH@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	TIGRFAM phenylalanyl-tRNA synthetase, beta subunit	pheT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
k59_28544_1	693977.Deipr_1618	1.28e-18	85.5	COG1947@1|root,COG1947@2|Bacteria,1WJXM@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	I	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol	ispE	GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515	2.7.1.148	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05634	RC00002,RC01439	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
k59_28544_2	335543.Sfum_3650	2.29e-31	114.0	2EAFJ@1|root,334IY@2|Bacteria,1NA2Y@1224|Proteobacteria,42VJ1@68525|delta/epsilon subdivisions,2WRKE@28221|Deltaproteobacteria,2MQME@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF1844)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1844
k59_165119_1	335543.Sfum_3649	1.03e-74	240.0	COG0111@1|root,COG0111@2|Bacteria,1MU5Z@1224|Proteobacteria,42M1C@68525|delta/epsilon subdivisions,2WIZQ@28221|Deltaproteobacteria,2MQZI@213462|Syntrophobacterales	28221|Deltaproteobacteria	EH	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic	-	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C,ACT
k59_135695_1	1444306.JFZC01000009_gene1914	4.96e-15	81.3	COG0714@1|root,COG1112@1|root,COG0714@2|Bacteria,COG1112@2|Bacteria,1TP20@1239|Firmicutes,4HDDW@91061|Bacilli	91061|Bacilli	L	Superfamily I DNA and RNA	-	-	-	-	-	-	-	-	-	-	-	-	AAA_11,AAA_12,DUF2726,DUF3320,DUF4011,DUF559
k59_143196_1	641491.DND132_1375	3.27e-108	320.0	COG0730@1|root,COG0730@2|Bacteria,1MWX2@1224|Proteobacteria,42R15@68525|delta/epsilon subdivisions,2WJR6@28221|Deltaproteobacteria,2MGF0@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
k59_89786_2	1307759.JOMJ01000003_gene1714	5.81e-121	377.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2WJ8D@28221|Deltaproteobacteria,2M7S1@213115|Desulfovibrionales	28221|Deltaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
k59_51466_1	177437.HRM2_18710	2.92e-44	162.0	COG0760@1|root,COG0760@2|Bacteria,1MWV0@1224|Proteobacteria,42MPK@68525|delta/epsilon subdivisions,2WJM1@28221|Deltaproteobacteria,2MHM6@213118|Desulfobacterales	28221|Deltaproteobacteria	O	PFAM PpiC-type peptidyl-prolyl cis-trans isomerase	nifM	-	5.2.1.8	ko:K03770	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N_3
k59_173151_1	589924.Ferp_1509	7.64e-58	200.0	COG0046@1|root,arCOG00641@2157|Archaea,2XU49@28890|Euryarchaeota,245S4@183980|Archaeoglobi	183980|Archaeoglobi	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
k59_158127_1	470145.BACCOP_01020	2.33e-45	167.0	COG1660@1|root,COG3178@1|root,COG1660@2|Bacteria,COG3178@2|Bacteria,4NIT0@976|Bacteroidetes,2FMEM@200643|Bacteroidia,4ANGQ@815|Bacteroidaceae	976|Bacteroidetes	S	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	APH,ATP_bind_2
k59_28552_1	1121405.dsmv_2218	9.59e-63	210.0	COG1960@1|root,COG1960@2|Bacteria,1NU73@1224|Proteobacteria,42Z96@68525|delta/epsilon subdivisions,2WTTK@28221|Deltaproteobacteria,2MN2J@213118|Desulfobacterales	28221|Deltaproteobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
k59_66620_1	1304885.AUEY01000002_gene375	3.84e-50	171.0	COG0524@1|root,COG0524@2|Bacteria,1MUUC@1224|Proteobacteria,42M1U@68525|delta/epsilon subdivisions,2WKK5@28221|Deltaproteobacteria,2MINI@213118|Desulfobacterales	28221|Deltaproteobacteria	G	pfkB family carbohydrate kinase	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
k59_66620_2	1232437.KL662066_gene4085	3.65e-11	57.4	COG3807@1|root,COG3807@2|Bacteria	2|Bacteria	S	protein conserved in bacteria	yrvJ	-	3.2.1.96,3.4.17.14,3.5.1.28	ko:K01227,ko:K01447,ko:K01448,ko:K06385,ko:K07260,ko:K11060,ko:K11062	ko00511,ko00550,ko01100,ko01502,ko01503,ko02020,map00511,map00550,map01100,map01502,map01503,map02020	M00651,M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504,ko02042,ko03036	-	-	-	Amidase_3,Glucosaminidase,NLPC_P60,SH3_3,SH3_4
k59_112719_2	273063.STK_17720	1.51e-11	68.2	COG1131@1|root,arCOG00194@2157|Archaea,2XPVP@28889|Crenarchaeota	28889|Crenarchaeota	V	TIGRFAM daunorubicin resistance ABC transporter ATPase subunit	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
k59_143215_1	857087.Metme_3144	8.25e-43	154.0	COG0767@1|root,COG0767@2|Bacteria,1MVPN@1224|Proteobacteria,1RYHN@1236|Gammaproteobacteria,1XDM2@135618|Methylococcales	135618|Methylococcales	Q	Permease MlaE	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
k59_234318_2	1121438.JNJA01000008_gene3908	1.33e-14	69.7	2AHS4@1|root,31H8F@2|Bacteria,1QEY4@1224|Proteobacteria,43631@68525|delta/epsilon subdivisions,2X0KX@28221|Deltaproteobacteria,2MCRZ@213115|Desulfovibrionales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_89799_1	1121405.dsmv_0430	3.73e-74	231.0	COG0501@1|root,COG0501@2|Bacteria,1MUV4@1224|Proteobacteria,42MEE@68525|delta/epsilon subdivisions,2WJYV@28221|Deltaproteobacteria,2MJ0G@213118|Desulfobacterales	28221|Deltaproteobacteria	O	Belongs to the peptidase M48B family	htpX	-	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	Peptidase_M48
k59_173161_1	1121456.ATVA01000011_gene1357	4.81e-44	162.0	COG3850@1|root,COG4191@1|root,COG3850@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42NFY@68525|delta/epsilon subdivisions,2WJKV@28221|Deltaproteobacteria,2M7VM@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	PFAM ATP-binding region ATPase domain protein	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_9
k59_112723_1	1279009.ADICEAN_02505	1.3e-101	318.0	COG0465@1|root,COG0465@2|Bacteria,4NF0E@976|Bacteroidetes,47KKF@768503|Cytophagia	976|Bacteroidetes	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
k59_14496_2	765952.PUV_27640	4.66e-49	166.0	COG0214@1|root,COG0214@2|Bacteria,2JG0Q@204428|Chlamydiae	204428|Chlamydiae	H	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively	pdxS	-	4.3.3.6	ko:K06215	ko00750,map00750	-	R07456	RC00010,RC01783,RC03043	ko00000,ko00001,ko01000	-	-	-	SOR_SNZ
k59_211445_1	1123248.KB893349_gene382	3.96e-14	75.9	COG4974@1|root,COG4974@2|Bacteria,4NGE1@976|Bacteroidetes,1IRMS@117747|Sphingobacteriia	976|Bacteroidetes	L	Phage integrase, N-terminal SAM-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
k59_21270_1	1267535.KB906767_gene4292	5.42e-27	107.0	COG2802@1|root,COG2802@2|Bacteria,3Y7UX@57723|Acidobacteria	57723|Acidobacteria	S	ATP-dependent protease La (LON) substrate-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LON_substr_bdg
k59_211452_1	439235.Dalk_3789	1.71e-128	383.0	COG0365@1|root,COG0365@2|Bacteria,1MUX7@1224|Proteobacteria,42P5R@68525|delta/epsilon subdivisions,2WJDU@28221|Deltaproteobacteria,2MI4P@213118|Desulfobacterales	28221|Deltaproteobacteria	I	PFAM AMP-dependent synthetase and ligase	-	-	6.2.1.16	ko:K01907	ko00280,ko00650,map00280,map00650	-	R01357	RC00004,RC00014	ko00000,ko00001,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
k59_165156_4	1235457.C404_22860	1.37e-06	49.3	COG1396@1|root,COG1396@2|Bacteria,1P08F@1224|Proteobacteria,2W75Q@28216|Betaproteobacteria,1KDW8@119060|Burkholderiaceae	28216|Betaproteobacteria	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
k59_51486_1	933262.AXAM01000046_gene136	2.66e-68	221.0	COG0606@1|root,COG0606@2|Bacteria,1MU4R@1224|Proteobacteria,42NBJ@68525|delta/epsilon subdivisions,2WJ52@28221|Deltaproteobacteria,2MHQI@213118|Desulfobacterales	28221|Deltaproteobacteria	O	chelatase, subunit ChlI	comM	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
k59_211460_1	515635.Dtur_1578	1.37e-05	50.1	COG1073@1|root,COG1073@2|Bacteria	2|Bacteria	S	thiolester hydrolase activity	yfhR3	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Abhydrolase_1,Hydrolase_4,Peptidase_S9
k59_195377_1	439235.Dalk_4284	1.32e-41	148.0	COG0017@1|root,COG0017@2|Bacteria,1MWFV@1224|Proteobacteria,42MJX@68525|delta/epsilon subdivisions,2WJDM@28221|Deltaproteobacteria,2MIBQ@213118|Desulfobacterales	28221|Deltaproteobacteria	J	class II (D K and N)	asnS	-	6.1.1.22	ko:K01893	ko00970,map00970	M00359,M00360	R03648	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
k59_195377_2	439235.Dalk_4147	1.98e-94	281.0	COG0207@1|root,COG0207@2|Bacteria,1Q4ZG@1224|Proteobacteria,42QWZ@68525|delta/epsilon subdivisions,2WMY5@28221|Deltaproteobacteria,2MJKN@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Thymidylate synthase	-	-	2.1.1.45	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	M00053	R02101	RC00219,RC00332	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylat_synt
k59_59794_1	398527.Bphyt_1683	2.18e-72	244.0	COG0515@1|root,COG2203@1|root,COG3899@1|root,COG4191@1|root,COG0515@2|Bacteria,COG2203@2|Bacteria,COG3899@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2VICN@28216|Betaproteobacteria,1K3Q3@119060|Burkholderiaceae	28216|Betaproteobacteria	T	ATP-binding region ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GAF,HATPase_c,HisKA,PAS_9,Pkinase
k59_66642_1	1144275.COCOR_04924	5.34e-13	72.8	COG0664@1|root,COG0664@2|Bacteria	2|Bacteria	T	cyclic nucleotide binding	-	-	1.8.1.9	ko:K00384,ko:K04739,ko:K07001,ko:K10914	ko00450,ko02020,ko02024,ko02025,ko02026,ko04910,ko05111,map00450,map02020,map02024,map02025,map02026,map04910,map05111	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000,ko03000	-	-	-	cNMP_binding
k59_158159_1	379066.GAU_1460	1.73e-34	132.0	COG0287@1|root,COG1605@1|root,COG0287@2|Bacteria,COG1605@2|Bacteria,1ZT61@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Chorismate mutase type II	-	-	1.3.1.12,5.4.99.5	ko:K14187	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00024,M00025	R01715,R01728	RC00125,RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	CM_2,PDH
k59_234342_1	1121405.dsmv_1758	6.25e-167	477.0	COG0493@1|root,COG0493@2|Bacteria,1MU2H@1224|Proteobacteria,42MGY@68525|delta/epsilon subdivisions,2WJHC@28221|Deltaproteobacteria,2MHYJ@213118|Desulfobacterales	28221|Deltaproteobacteria	E	TIGRFAM glutamate synthase (NADPH), homotetrameric	-	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	Fer4_20,Pyr_redox_2
k59_173203_1	1123489.AUAN01000002_gene741	1.22e-29	114.0	COG2890@1|root,COG2890@2|Bacteria,1TSMA@1239|Firmicutes,4H2VA@909932|Negativicutes	909932|Negativicutes	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif	prmC	-	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS,Methyltransf_31
k59_173203_2	177437.HRM2_17080	9.43e-24	99.8	COG0216@1|root,COG0216@2|Bacteria,1MV28@1224|Proteobacteria,42NA3@68525|delta/epsilon subdivisions,2WIQU@28221|Deltaproteobacteria,2MHQM@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
k59_195391_1	1352941.M877_38825	1.52e-32	125.0	COG1131@1|root,COG1131@2|Bacteria,2GIY8@201174|Actinobacteria	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
k59_14537_1	1121428.DESHY_110411___1	9.6e-10	63.5	COG0493@1|root,COG1148@1|root,COG0493@2|Bacteria,COG1148@2|Bacteria,1TQ1A@1239|Firmicutes,248EK@186801|Clostridia,26166@186807|Peptococcaceae	186801|Clostridia	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_20,Fer4_7,NAD_binding_8,Pyr_redox_2
k59_74692_1	1227497.C491_14422	1.73e-40	148.0	COG1804@1|root,arCOG02304@2157|Archaea,2XVUE@28890|Euryarchaeota,23UHK@183963|Halobacteria	183963|Halobacteria	C	acyl-CoA transferases carnitine dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
k59_14538_1	1121405.dsmv_0564	4.23e-81	271.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1MXBU@1224|Proteobacteria,42M59@68525|delta/epsilon subdivisions,2WIUK@28221|Deltaproteobacteria,2MICN@213118|Desulfobacterales	28221|Deltaproteobacteria	G	Pyruvate phosphate dikinase, PEP	-	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PPDK_N
k59_51506_1	365044.Pnap_1343	5.45e-36	138.0	COG0644@1|root,COG0644@2|Bacteria,1MZVI@1224|Proteobacteria,2VH6J@28216|Betaproteobacteria,4ABDG@80864|Comamonadaceae	28216|Betaproteobacteria	C	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Trp_halogenase
k59_135765_1	658086.HMPREF0994_05278	7.18e-33	125.0	COG1214@1|root,COG1214@2|Bacteria,1V4YX@1239|Firmicutes,24A0P@186801|Clostridia,27IG5@186928|unclassified Lachnospiraceae	186801|Clostridia	O	Glycoprotease family	yeaZ	-	-	ko:K14742	-	-	-	-	ko00000,ko03016	-	-	-	Acetyltransf_1,Peptidase_M22
k59_85947_1	589865.DaAHT2_1282	5.67e-112	335.0	COG0112@1|root,COG0112@2|Bacteria,1MUIS@1224|Proteobacteria,42M0T@68525|delta/epsilon subdivisions,2WJ3C@28221|Deltaproteobacteria,2MHY8@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
k59_146673_1	338963.Pcar_3003	1.15e-75	253.0	COG1538@1|root,COG1538@2|Bacteria,1MYXE@1224|Proteobacteria,42TA7@68525|delta/epsilon subdivisions,2WR7T@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
k59_93649_1	443152.MDG893_04382	7.58e-41	153.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,464D1@72275|Alteromonadaceae	1236|Gammaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K18138	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
k59_40659_2	1125863.JAFN01000001_gene3302	2.68e-52	167.0	COG0197@1|root,COG0197@2|Bacteria,1RA0Z@1224|Proteobacteria,42QW5@68525|delta/epsilon subdivisions,2WP71@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs	rplP	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904	-	ko:K02878	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L16
k59_207598_1	1219076.N646_4610	1.85e-18	88.6	COG0568@1|root,COG0568@2|Bacteria,1MUDI@1224|Proteobacteria,1RN8V@1236|Gammaproteobacteria,1XSEF@135623|Vibrionales	135623|Vibrionales	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	-	-	-	ko:K03087	ko02026,ko05111,map02026,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r4
k59_214866_2	933262.AXAM01000023_gene647	7.36e-19	89.0	COG0544@1|root,COG0544@2|Bacteria,1MUJP@1224|Proteobacteria,42MBB@68525|delta/epsilon subdivisions,2WIU1@28221|Deltaproteobacteria,2MHZ5@213118|Desulfobacterales	28221|Deltaproteobacteria	D	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C,Trigger_N
k59_146676_1	391595.RLO149_c022170	0.000896	45.1	2CDFF@1|root,31AC8@2|Bacteria,1Q5BT@1224|Proteobacteria,2VBQG@28211|Alphaproteobacteria,2P535@2433|Roseobacter	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_146676_2	63737.Npun_R1245	1.67e-50	164.0	2D8VC@1|root,32TS1@2|Bacteria,1G8H1@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_146676_3	243231.GSU2788	1.54e-90	270.0	COG1765@1|root,COG1765@2|Bacteria,1MWPR@1224|Proteobacteria,42S3G@68525|delta/epsilon subdivisions,2WNET@28221|Deltaproteobacteria,43UXB@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	OsmC-like protein	-	-	-	-	-	-	-	-	-	-	-	-	OsmC
k59_116198_1	235985.BBPN01000008_gene4114	2.83e-08	58.9	COG5553@1|root,COG5553@2|Bacteria,2I8K9@201174|Actinobacteria,2NMQG@228398|Streptacidiphilus	201174|Actinobacteria	S	Cysteine dioxygenase type I	-	-	-	-	-	-	-	-	-	-	-	-	CDO_I
k59_17753_1	1121422.AUMW01000013_gene1529	1.01e-18	86.7	COG0699@1|root,COG0699@2|Bacteria,1TR0Q@1239|Firmicutes,24BWJ@186801|Clostridia,261EP@186807|Peptococcaceae	186801|Clostridia	S	Dynamin family	-	-	-	-	-	-	-	-	-	-	-	-	Dynamin_N
k59_93670_1	887327.HMPREF0476_0239	1.12e-27	106.0	COG0782@1|root,COG0782@2|Bacteria,1RCXW@1224|Proteobacteria,2VQ16@28216|Betaproteobacteria,2KQY9@206351|Neisseriales	206351|Neisseriales	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	-	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
k59_207614_1	398720.MED217_12439	9.15e-22	86.3	2EPEC@1|root,33H0Y@2|Bacteria,4P4SQ@976|Bacteroidetes,1I9R8@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_33027_1	1380386.JIAW01000001_gene4848	1.91e-16	80.9	COG1233@1|root,COG1233@2|Bacteria,2GMUC@201174|Actinobacteria,234PD@1762|Mycobacteriaceae	201174|Actinobacteria	Q	NAD(P)-binding Rossmann-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
k59_33027_2	909663.KI867150_gene2418	3.85e-40	150.0	COG3848@1|root,COG3848@2|Bacteria,1MV5C@1224|Proteobacteria,43B08@68525|delta/epsilon subdivisions,2X6EC@28221|Deltaproteobacteria	1224|Proteobacteria	T	PEP-utilising enzyme, mobile domain	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers
k59_93672_1	1379281.AVAG01000021_gene1108	1.27e-262	749.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,42M51@68525|delta/epsilon subdivisions,2WIPP@28221|Deltaproteobacteria,2M915@213115|Desulfovibrionales	28221|Deltaproteobacteria	NU	PFAM Type II secretion system protein E	gspE	-	-	ko:K02454	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	GAF,T2SSE,T2SSE_N
k59_139393_1	1131730.BAVI_09741	4.79e-73	231.0	COG0334@1|root,COG0334@2|Bacteria,1TQU2@1239|Firmicutes,4HAB2@91061|Bacilli,1ZB55@1386|Bacillus	91061|Bacilli	E	Belongs to the Glu Leu Phe Val dehydrogenases family	-	-	1.4.1.20	ko:K00270	ko00350,ko00360,ko00400,ko01100,ko01110,ko01130,map00350,map00360,map00400,map01100,map01110,map01130	-	R00688,R09830	RC00006	ko00000,ko00001,ko01000	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
k59_124307_1	159087.Daro_2284	1.68e-17	77.8	COG2963@1|root,COG2963@2|Bacteria,1N06K@1224|Proteobacteria,2VUF3@28216|Betaproteobacteria,2KZ7Q@206389|Rhodocyclales	206389|Rhodocyclales	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Tnp_1
k59_124307_2	1088721.NSU_4947	1.83e-54	180.0	COG2801@1|root,COG2801@2|Bacteria,1MVC8@1224|Proteobacteria,2TRX0@28211|Alphaproteobacteria,2K3CJ@204457|Sphingomonadales	204457|Sphingomonadales	L	Integrase core domain	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve
k59_192190_1	335543.Sfum_3466	2.21e-68	225.0	COG0769@1|root,COG0769@2|Bacteria,1MU6P@1224|Proteobacteria,42NKY@68525|delta/epsilon subdivisions,2WJJG@28221|Deltaproteobacteria,2MR5A@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008765,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
k59_124308_1	335543.Sfum_3743	2.09e-51	176.0	COG4591@1|root,COG4591@2|Bacteria,1MVV7@1224|Proteobacteria,42MV0@68525|delta/epsilon subdivisions,2WITK@28221|Deltaproteobacteria,2MQRN@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	TIGRFAM Lipoprotein releasing system, transmembrane protein, LolC E family	lolC	-	-	ko:K09808	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125	-	-	FtsX,MacB_PCD
k59_40696_1	756067.MicvaDRAFT_5445	1.66e-26	114.0	COG0810@1|root,COG1404@1|root,COG2931@1|root,COG0810@2|Bacteria,COG1404@2|Bacteria,COG2931@2|Bacteria,1G3AC@1117|Cyanobacteria,1HE4V@1150|Oscillatoriales	1117|Cyanobacteria	Q	PFAM Peptidase C11, clostripain	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,DUF4347,HemolysinCabind,Peptidase_C11,VCBS
k59_78725_1	335543.Sfum_2069	6.58e-151	440.0	COG1508@1|root,COG1508@2|Bacteria,1MW4V@1224|Proteobacteria,42M3C@68525|delta/epsilon subdivisions,2WJ21@28221|Deltaproteobacteria,2MQBH@213462|Syntrophobacterales	28221|Deltaproteobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	rpoN	-	-	ko:K03092	ko02020,ko05111,map02020,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma54_AID,Sigma54_CBD,Sigma54_DBD
k59_222783_1	290400.Jann_0261	1.96e-23	104.0	COG0111@1|root,COG0111@2|Bacteria,1MU5Z@1224|Proteobacteria,2TR0F@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family	serA	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C,ACT
k59_184975_1	864069.MicloDRAFT_00005550	7.87e-72	228.0	COG3415@1|root,COG3415@2|Bacteria,1QWT2@1224|Proteobacteria,2TX4K@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	Rhodopirellula transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISAZ013
k59_85964_1	1265505.ATUG01000002_gene1212	1.75e-39	138.0	COG2197@1|root,COG2197@2|Bacteria,1MWGM@1224|Proteobacteria,42R03@68525|delta/epsilon subdivisions,2WMTZ@28221|Deltaproteobacteria,2MJ7X@213118|Desulfobacterales	28221|Deltaproteobacteria	T	PFAM response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
k59_146700_1	880072.Desac_2722	3.59e-88	275.0	COG1190@1|root,COG1190@2|Bacteria,1MX1V@1224|Proteobacteria,42M90@68525|delta/epsilon subdivisions,2WJ9G@28221|Deltaproteobacteria,2MQW7@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	Belongs to the class-II aminoacyl-tRNA synthetase family	lysS	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
k59_177152_1	706587.Desti_1825	1.77e-109	324.0	COG1748@1|root,COG1748@2|Bacteria,1NIU2@1224|Proteobacteria,42MHS@68525|delta/epsilon subdivisions,2WJQW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	PFAM Saccharopine dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Sacchrp_dh_C,Sacchrp_dh_NADP
k59_207651_1	1123037.AUDE01000046_gene849	1.09e-59	197.0	COG1228@1|root,COG1228@2|Bacteria,4NFI3@976|Bacteroidetes,1HY2V@117743|Flavobacteriia	976|Bacteroidetes	Q	Imidazolonepropionase and related	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
k59_237886_1	32057.KB217483_gene9456	9.09e-95	286.0	COG5433@1|root,COG5433@2|Bacteria,1G0VN@1117|Cyanobacteria,1HJR6@1161|Nostocales	1117|Cyanobacteria	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_assoc
k59_162082_1	289376.THEYE_A1636	2.9e-33	125.0	COG2086@1|root,COG2086@2|Bacteria	2|Bacteria	C	electron transfer activity	etfB	GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016020,GO:0016491,GO:0022900,GO:0030312,GO:0040007,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0071944	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
k59_101546_1	1167006.UWK_00139	1.9e-24	97.1	COG0764@1|root,COG0764@2|Bacteria,1NNU2@1224|Proteobacteria,437EX@68525|delta/epsilon subdivisions,2X2M8@28221|Deltaproteobacteria,2MP7V@213118|Desulfobacterales	28221|Deltaproteobacteria	I	FabA-like domain	-	-	-	-	-	-	-	-	-	-	-	-	FabA
k59_101546_2	1167006.UWK_00140	4e-38	129.0	COG0236@1|root,COG0236@2|Bacteria	2|Bacteria	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	-	GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
k59_101546_3	1167006.UWK_00141	7.62e-36	131.0	COG0535@1|root,COG0535@2|Bacteria	2|Bacteria	I	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Fer4_14,Radical_SAM,SPASM
k59_116235_1	886293.Sinac_3637	4.98e-44	163.0	COG0764@1|root,COG3321@1|root,COG0764@2|Bacteria,COG3321@2|Bacteria,2IYQE@203682|Planctomycetes	203682|Planctomycetes	IQ	FabA-like domain	-	-	-	-	-	-	-	-	-	-	-	-	FabA,Ketoacyl-synt_C,ketoacyl-synt
k59_230203_1	1499967.BAYZ01000151_gene1668	8.86e-108	341.0	COG0841@1|root,COG0841@2|Bacteria,2NNUH@2323|unclassified Bacteria	2|Bacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
k59_63517_1	177437.HRM2_12360	3.72e-13	64.3	2EJAZ@1|root,3356X@2|Bacteria,1NFZK@1224|Proteobacteria,42V0Q@68525|delta/epsilon subdivisions,2WS7N@28221|Deltaproteobacteria,2MMC0@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_207653_1	1408422.JHYF01000001_gene2801	5.41e-32	127.0	COG2804@1|root,COG2804@2|Bacteria,1TPGE@1239|Firmicutes,247KA@186801|Clostridia,36DG2@31979|Clostridiaceae	186801|Clostridia	NU	type II secretion system protein E	xcpR	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE,T2SSE_N
k59_184989_1	3880.AET02208	7.18e-19	84.7	COG0115@1|root,KOG0975@2759|Eukaryota	2759|Eukaryota	E	branched-chain-amino-acid transaminase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_101552_2	1232437.KL662036_gene2708	1.09e-34	122.0	COG0748@1|root,COG0748@2|Bacteria,1N2JV@1224|Proteobacteria,42TYW@68525|delta/epsilon subdivisions,2WQEM@28221|Deltaproteobacteria,2MK6D@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Pfam:Pyridox_oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
k59_131742_1	335543.Sfum_1795	1.82e-72	233.0	COG3383@1|root,COG3383@2|Bacteria,1QTZB@1224|Proteobacteria,42SPZ@68525|delta/epsilon subdivisions,2WIV9@28221|Deltaproteobacteria,2MRHE@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Fer2_4,Fer4_7,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
k59_63527_1	7955.ENSDARP00000106282	5.43e-34	135.0	KOG1075@1|root,KOG1075@2759|Eukaryota,39Y6T@33154|Opisthokonta,3BEGN@33208|Metazoa,3CZ7K@33213|Bilateria,48DPU@7711|Chordata,49A9G@7742|Vertebrata	33208|Metazoa	S	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos_2,RVT_1
k59_2586_1	1382304.JNIL01000001_gene2310	3.18e-59	202.0	COG0247@1|root,COG0247@2|Bacteria,1TPG1@1239|Firmicutes,4HB2J@91061|Bacilli,277YN@186823|Alicyclobacillaceae	91061|Bacilli	C	4Fe-4S dicluster domain	ywjF	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_8
k59_131748_1	631362.Thi970DRAFT_00760	1.49e-45	160.0	COG2995@1|root,COG2995@2|Bacteria,1MWG1@1224|Proteobacteria,1RM9Z@1236|Gammaproteobacteria,1WX87@135613|Chromatiales	135613|Chromatiales	S	PFAM Paraquat-inducible protein A	-	-	-	ko:K03808	-	-	-	-	ko00000	-	-	-	PqiA
k59_131748_2	933262.AXAM01000106_gene2631	1.9e-23	99.0	COG2995@1|root,COG2995@2|Bacteria,1MWG1@1224|Proteobacteria,42R11@68525|delta/epsilon subdivisions,2WMWN@28221|Deltaproteobacteria,2MMZB@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Paraquat-inducible protein A	-	-	-	ko:K03808	-	-	-	-	ko00000	-	-	-	PqiA
k59_169461_1	1121405.dsmv_0036	3.36e-116	360.0	COG0060@1|root,COG0060@2|Bacteria,1MVBQ@1224|Proteobacteria,42MKB@68525|delta/epsilon subdivisions,2WJ4W@28221|Deltaproteobacteria,2MI4Z@213118|Desulfobacterales	28221|Deltaproteobacteria	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1,zf-FPG_IleRS
k59_237916_1	644282.Deba_2592	3.7e-17	87.0	COG0863@1|root,COG1475@1|root,COG0863@2|Bacteria,COG1475@2|Bacteria,1RD30@1224|Proteobacteria,42NX1@68525|delta/epsilon subdivisions,2WTTS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	KL	DNA methylase	-	-	-	-	-	-	-	-	-	-	-	-	N6_N4_Mtase
k59_56006_1	335543.Sfum_1234	3.06e-80	259.0	COG1185@1|root,COG1185@2|Bacteria,1MVB9@1224|Proteobacteria,42MTZ@68525|delta/epsilon subdivisions,2WJCE@28221|Deltaproteobacteria,2MQ7E@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004654,GO:0005488,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
k59_56006_2	1232410.KI421413_gene522	4.97e-41	136.0	COG0184@1|root,COG0184@2|Bacteria,1MZ2W@1224|Proteobacteria,42TPZ@68525|delta/epsilon subdivisions,2WQ0P@28221|Deltaproteobacteria,43SNS@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Ribosomal_S15	rpsO	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
k59_185006_2	909663.KI867150_gene2871	1.87e-107	326.0	COG3039@1|root,COG3039@2|Bacteria,1QY2X@1224|Proteobacteria	1224|Proteobacteria	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_6
k59_48598_1	485915.Dret_2384	4.46e-44	148.0	COG3005@1|root,COG3005@2|Bacteria,1RIC0@1224|Proteobacteria,42NW0@68525|delta/epsilon subdivisions,2WK0R@28221|Deltaproteobacteria,2MB00@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	Cytochrome c-type protein	-	-	-	ko:K02569,ko:K03532	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	5.A.3.4	-	-	Cytochrom_NNT
k59_48598_2	879212.DespoDRAFT_01337	4.41e-54	183.0	COG3303@1|root,COG3303@2|Bacteria,1P8CP@1224|Proteobacteria,42MXS@68525|delta/epsilon subdivisions,2WKEK@28221|Deltaproteobacteria,2MI5R@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Seven times multi-haem cytochrome CxxCH	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554,Multi-haem_cyto
k59_109222_1	1009370.ALO_11644	1.9e-21	99.0	COG0243@1|root,COG0243@2|Bacteria,1TPZG@1239|Firmicutes,4H4MY@909932|Negativicutes	909932|Negativicutes	C	Anaerobic dimethyl sulfoxide reductase, A subunit, DmsA YnfE	-	-	1.8.5.3	ko:K07306	ko00920,map00920	-	R09501	RC02555	ko00000,ko00001,ko01000,ko02000	5.A.3.3	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
k59_230840_1	1196322.A370_04081	3.37e-31	118.0	COG1413@1|root,COG1413@2|Bacteria,1VTQX@1239|Firmicutes,24J5Z@186801|Clostridia,36J93@31979|Clostridiaceae	186801|Clostridia	C	lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_185609_1	933262.AXAM01000058_gene3196	7.8e-64	219.0	COG0574@1|root,COG0745@1|root,COG0574@2|Bacteria,COG0745@2|Bacteria,1N38V@1224|Proteobacteria,42MWC@68525|delta/epsilon subdivisions,2WKAZ@28221|Deltaproteobacteria,2MICZ@213118|Desulfobacterales	28221|Deltaproteobacteria	GT	pyruvate phosphate dikinase	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_2,PPDK_N
k59_155124_1	933262.AXAM01000016_gene149	3.44e-70	234.0	COG5009@1|root,COG5009@2|Bacteria,1MU5A@1224|Proteobacteria,42MJB@68525|delta/epsilon subdivisions,2WIXF@28221|Deltaproteobacteria,2MI9W@213118|Desulfobacterales	28221|Deltaproteobacteria	M	TIGRFAM penicillin-binding protein, 1A family	mrcA	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	iAF987.Gmet_0354	PCB_OB,Transgly,Transpeptidase
k59_63986_1	589865.DaAHT2_1221	2.63e-98	303.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,42MGZ@68525|delta/epsilon subdivisions,2WIY6@28221|Deltaproteobacteria,2MHSH@213118|Desulfobacterales	28221|Deltaproteobacteria	L	DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA	rhlB	-	3.6.4.13	ko:K03732	ko03018,map03018	M00394	-	-	ko00000,ko00001,ko00002,ko01000,ko03019	-	-	-	DEAD,Helicase_C,R3H
k59_169984_1	330214.NIDE1386	3.95e-71	228.0	COG0015@1|root,COG0015@2|Bacteria,3J0EM@40117|Nitrospirae	40117|Nitrospirae	F	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	purB	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ADSL_C,Lyase_1
k59_48605_1	1565129.JSFF01000060_gene678	6.83e-29	115.0	COG3385@1|root,COG3385@2|Bacteria,1R55Y@1224|Proteobacteria,1RRSD@1236|Gammaproteobacteria,2QBDP@267890|Shewanellaceae	1236|Gammaproteobacteria	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
k59_200390_1	998674.ATTE01000001_gene4190	9.24e-58	195.0	COG1271@1|root,COG1271@2|Bacteria,1MV60@1224|Proteobacteria,1RN2U@1236|Gammaproteobacteria,45ZXF@72273|Thiotrichales	72273|Thiotrichales	C	Cytochrome bd ubiquinol oxidase, subunit I	-	-	1.10.3.14	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	Cyt_bd_oxida_I
k59_200390_2	1150626.PHAMO_210342	8.64e-108	321.0	COG1294@1|root,COG1294@2|Bacteria,1MURP@1224|Proteobacteria,2TU3I@28211|Alphaproteobacteria,2JQ3X@204441|Rhodospirillales	204441|Rhodospirillales	C	oxidase, subunit	cydB	-	1.10.3.14	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	Cyt_bd_oxida_II
k59_86461_1	1347369.CCAD010000056_gene4248	1.55e-17	84.0	COG3509@1|root,COG3509@2|Bacteria,1UZP5@1239|Firmicutes,4HAWI@91061|Bacilli,1ZF2M@1386|Bacillus	91061|Bacilli	Q	Esterase PHB depolymerase	phaZ	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,Esterase_phd
k59_102071_1	1121405.dsmv_0408	3.42e-125	384.0	COG0517@1|root,COG0617@1|root,COG0618@1|root,COG0517@2|Bacteria,COG0617@2|Bacteria,COG0618@2|Bacteria,1MU2X@1224|Proteobacteria,42MJJ@68525|delta/epsilon subdivisions,2WJBN@28221|Deltaproteobacteria,2MI4C@213118|Desulfobacterales	28221|Deltaproteobacteria	J	CBS domain	ccaA	-	2.7.7.72	ko:K00974	ko03013,map03013	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016	-	-	-	CBS,DHH,DHHA1,PolyA_pol,PolyA_pol_RNAbd
k59_109236_1	1499967.BAYZ01000036_gene2438	1.3e-50	169.0	COG0330@1|root,COG0330@2|Bacteria,2NP2X@2323|unclassified Bacteria	2|Bacteria	O	HflC and HflK could regulate a protease	hflC	-	-	ko:K04087	-	M00742	-	-	ko00000,ko00002,ko01000	-	-	-	Band_7
k59_109236_2	1121403.AUCV01000056_gene3021	9.89e-24	98.2	COG0330@1|root,COG0330@2|Bacteria,1MUM2@1224|Proteobacteria,42NUT@68525|delta/epsilon subdivisions,2WKQX@28221|Deltaproteobacteria,2MI5I@213118|Desulfobacterales	28221|Deltaproteobacteria	O	HflC and HflK could encode or regulate a protease	hflK	-	-	ko:K04088	-	M00742	-	-	ko00000,ko00002,ko01000	-	-	-	Band_7
k59_56492_1	439235.Dalk_2558	2.43e-79	239.0	COG1905@1|root,COG1905@2|Bacteria,1RHBU@1224|Proteobacteria,42U8S@68525|delta/epsilon subdivisions,2WQ8V@28221|Deltaproteobacteria,2MKT7@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit	nuoE-1	-	1.6.5.3	ko:K00334	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx
k59_56492_2	439235.Dalk_2559	0.000425	42.4	COG0493@1|root,COG1894@1|root,COG0493@2|Bacteria,COG1894@2|Bacteria,1MV8F@1224|Proteobacteria,42N6N@68525|delta/epsilon subdivisions,2WJ1W@28221|Deltaproteobacteria,2MJ8N@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Respiratory-chain NADH dehydrogenase domain 51 kDa subunit	-	-	1.12.1.3,1.6.5.2,1.6.5.3	ko:K00124,ko:K00335,ko:K00355,ko:K18331	ko00130,ko00190,ko00630,ko00680,ko01100,ko01110,ko01120,ko01200,ko05200,ko05225,ko05418,map00130,map00190,map00630,map00680,map01100,map01110,map01120,map01200,map05200,map05225,map05418	M00144	R00519,R02964,R03643,R03816,R11945	RC00061,RC00819,RC02796	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx,Complex1_51K,Fer4,NADH_4Fe-4S,SLBB
k59_200395_1	525904.Tter_0370	3.33e-11	67.0	COG0619@1|root,COG0619@2|Bacteria,2NRH2@2323|unclassified Bacteria	2|Bacteria	P	Cobalt transport protein	-	-	-	ko:K16785,ko:K16786,ko:K16787	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	CbiQ
k59_102072_1	335543.Sfum_1893	2.43e-11	70.1	COG3210@1|root,COG4723@1|root,COG4733@1|root,COG3210@2|Bacteria,COG4723@2|Bacteria,COG4733@2|Bacteria,1MXXZ@1224|Proteobacteria,42QDD@68525|delta/epsilon subdivisions,2WIU9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	U	Phage-related protein, tail	-	-	-	-	-	-	-	-	-	-	-	-	Phage-tail_3
k59_71423_1	96561.Dole_0844	1.65e-127	375.0	COG0593@1|root,COG1943@1|root,COG0593@2|Bacteria,COG1943@2|Bacteria,1MX0E@1224|Proteobacteria,42NN0@68525|delta/epsilon subdivisions,2WM14@28221|Deltaproteobacteria,2MIW7@213118|Desulfobacterales	28221|Deltaproteobacteria	L	SMART Chromosomal replication initiator DnaA domain	-	-	-	-	-	-	-	-	-	-	-	-	Bac_DnaA_C,Y1_Tnp
k59_41110_1	1121403.AUCV01000007_gene1200	2.49e-100	316.0	COG1215@1|root,COG1215@2|Bacteria,1NQ1J@1224|Proteobacteria,42ZP1@68525|delta/epsilon subdivisions	1224|Proteobacteria	M	Glycosyl transferase family group 2	alg8	-	2.4.1.33	ko:K19290	ko00051,map00051	-	R08692	RC00005	ko00000,ko00001,ko01000,ko01003,ko02000	4.D.1.1.7,4.D.1.1.9	GT2	-	Glyco_tranf_2_3
k59_238281_1	335543.Sfum_0063	2.34e-157	453.0	COG4992@1|root,COG4992@2|Bacteria,1MV3C@1224|Proteobacteria,42MHH@68525|delta/epsilon subdivisions,2WIMW@28221|Deltaproteobacteria,2MQ76@213462|Syntrophobacterales	28221|Deltaproteobacteria	E	TIGRFAM acetylornithine and succinylornithine	argD	-	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	iAF987.Gmet_0204	Aminotran_3
k59_109246_1	1415778.JQMM01000001_gene809	5.18e-41	149.0	COG0793@1|root,COG0793@2|Bacteria,1MU39@1224|Proteobacteria,1RMSR@1236|Gammaproteobacteria,1J4IS@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	Belongs to the peptidase S41A family	ctpA	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_S41
k59_56498_1	335543.Sfum_1817	3.12e-34	131.0	COG0661@1|root,COG0661@2|Bacteria,1MU1Z@1224|Proteobacteria,42N87@68525|delta/epsilon subdivisions,2WK1B@28221|Deltaproteobacteria,2MRH3@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	ABC1 family	-	-	-	ko:K03688	-	-	-	-	ko00000	-	-	-	ABC1,RIO1
k59_195563_1	1380384.JADN01000009_gene237	5.15e-27	115.0	COG1300@1|root,COG1300@2|Bacteria,4NG8D@976|Bacteroidetes,1HWW9@117743|Flavobacteriia	976|Bacteroidetes	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIM
k59_218666_1	63737.Npun_F3747	6.41e-85	260.0	COG1091@1|root,COG1091@2|Bacteria,1G3IE@1117|Cyanobacteria,1HJTK@1161|Nostocales	1117|Cyanobacteria	M	PFAM RmlD substrate binding domain	rmlD	-	1.1.1.133	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777	RC00182	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
k59_44043_1	1123504.JQKD01000038_gene3013	3.93e-28	114.0	COG0559@1|root,COG4177@1|root,COG0559@2|Bacteria,COG4177@2|Bacteria,1MY1E@1224|Proteobacteria,2VMZ5@28216|Betaproteobacteria,4AB9X@80864|Comamonadaceae	28216|Betaproteobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01997,ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
k59_173373_1	933262.AXAM01000001_gene339	2.07e-90	277.0	COG0304@1|root,COG0304@2|Bacteria,1MU1X@1224|Proteobacteria,42MUZ@68525|delta/epsilon subdivisions,2WJT6@28221|Deltaproteobacteria,2MHUV@213118|Desulfobacterales	28221|Deltaproteobacteria	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabF	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
k59_173373_2	1121405.dsmv_2216	2.26e-28	103.0	COG0236@1|root,COG0236@2|Bacteria,1MZ4P@1224|Proteobacteria,42V9M@68525|delta/epsilon subdivisions,2WRDW@28221|Deltaproteobacteria,2MKUS@213118|Desulfobacterales	28221|Deltaproteobacteria	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
k59_74816_1	933262.AXAM01000013_gene1324	6.71e-87	280.0	COG0532@1|root,COG0532@2|Bacteria,1MV26@1224|Proteobacteria,42M5Q@68525|delta/epsilon subdivisions,2WIIX@28221|Deltaproteobacteria,2MIGT@213118|Desulfobacterales	28221|Deltaproteobacteria	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,IF-2,IF2_N
k59_226267_1	706587.Desti_4840	6.51e-08	53.5	COG0607@1|root,COG1633@1|root,COG0607@2|Bacteria,COG1633@2|Bacteria,1MZPW@1224|Proteobacteria,42NX5@68525|delta/epsilon subdivisions,2WMJ4@28221|Deltaproteobacteria,2MRIH@213462|Syntrophobacterales	28221|Deltaproteobacteria	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese,Rubrerythrin
k59_226267_2	1499967.BAYZ01000019_gene6299	1.39e-34	123.0	COG1633@1|root,COG1633@2|Bacteria	2|Bacteria	S	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)	-	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
k59_158361_1	96561.Dole_2491	3.48e-76	239.0	COG0137@1|root,COG0137@2|Bacteria,1MV0Y@1224|Proteobacteria,42N81@68525|delta/epsilon subdivisions,2WJB0@28221|Deltaproteobacteria,2MIV2@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Belongs to the argininosuccinate synthase family. Type 1 subfamily	argG	GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Arginosuc_synth
k59_180561_1	754252.PFREUD_06790	1.8e-10	67.0	COG1502@1|root,COG1502@2|Bacteria,2GM0P@201174|Actinobacteria,4DP3Y@85009|Propionibacteriales	201174|Actinobacteria	I	Phospholipase D. Active site motifs.	-	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2
k59_143525_2	485916.Dtox_4070	9.6e-57	186.0	COG3385@1|root,COG3385@2|Bacteria,1TSGW@1239|Firmicutes,24E38@186801|Clostridia	186801|Clostridia	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_5,DDE_Tnp_1
k59_119964_1	765420.OSCT_2092	1.98e-12	70.1	COG2203@1|root,COG2208@1|root,COG2203@2|Bacteria,COG2208@2|Bacteria,2G790@200795|Chloroflexi,375DF@32061|Chloroflexia	32061|Chloroflexia	T	SMART protein phosphatase 2C domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,SpoIIE
k59_128068_1	247633.GP2143_15086	2.34e-06	55.8	COG0557@1|root,COG0557@2|Bacteria,1R33Q@1224|Proteobacteria,1T62R@1236|Gammaproteobacteria,1J5FB@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	Belongs to the RNR ribonuclease family	-	-	3.1.13.1	ko:K01147,ko:K12573	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	OB_RNB,RNB,S1
k59_203849_1	755731.Clo1100_3901	6.17e-54	183.0	COG0566@1|root,COG0566@2|Bacteria,1TP9G@1239|Firmicutes,247SC@186801|Clostridia,36DW4@31979|Clostridiaceae	186801|Clostridia	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	yacO	-	2.1.1.185	ko:K03218	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SpoU_methylase,SpoU_sub_bind
k59_218681_1	525378.HMPREF0793_1950	2.1e-11	69.3	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,1TP3F@1239|Firmicutes,4H9KD@91061|Bacilli,4GY5R@90964|Staphylococcaceae	91061|Bacilli	KLT	Serine threonine protein kinase	prkC	GO:0002237,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005539,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009617,GO:0009719,GO:0009847,GO:0009987,GO:0010033,GO:0010243,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0023052,GO:0032494,GO:0032502,GO:0036211,GO:0042221,GO:0042834,GO:0043170,GO:0043207,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051704,GO:0051707,GO:0051716,GO:0065007,GO:0070887,GO:0071216,GO:0071219,GO:0071224,GO:0071310,GO:0071417,GO:0071495,GO:0071704,GO:0071944,GO:0097367,GO:0140096,GO:1901564,GO:1901698,GO:1901699,GO:1901700,GO:1901701	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
k59_143530_1	436308.Nmar_0801	1.36e-19	82.8	COG0186@1|root,arCOG04096@2157|Archaea,41SSH@651137|Thaumarchaeota	651137|Thaumarchaeota	J	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA	rps17	-	-	ko:K02961	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S17
k59_143530_2	267377.MMP1407	4.08e-15	71.2	COG1588@1|root,arCOG00784@2157|Archaea,2XYYU@28890|Euryarchaeota,23R6Y@183939|Methanococci	183939|Methanococci	J	Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends	rnp1	GO:0000966,GO:0001682,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0030677,GO:0032991,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0099116,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1902555,GO:1905348,GO:1990904	3.1.26.5	ko:K03538	ko03008,ko03013,map03008,map03013	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03016,ko03029	-	-	-	UPF0086
k59_143535_1	1232437.KL662020_gene700	3.64e-27	114.0	COG0845@1|root,COG0845@2|Bacteria,1MU8D@1224|Proteobacteria,42PAC@68525|delta/epsilon subdivisions,2WKAD@28221|Deltaproteobacteria,2MMGU@213118|Desulfobacterales	28221|Deltaproteobacteria	M	HlyD membrane-fusion protein of T1SS	-	-	-	ko:K02005,ko:K13888	-	M00709	-	-	ko00000,ko00002,ko02000	8.A.1	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
k59_165386_1	1283300.ATXB01000001_gene2071	1.94e-42	154.0	COG1858@1|root,COG1858@2|Bacteria,1MV70@1224|Proteobacteria,1RPPQ@1236|Gammaproteobacteria,1XERF@135618|Methylococcales	135618|Methylococcales	C	PFAM Di-haem cytochrome c peroxidase	-	-	1.11.1.5	ko:K00428	-	-	-	-	ko00000,ko01000	-	-	-	CCP_MauG,Cytochrom_C
k59_211716_1	1499967.BAYZ01000076_gene816	1.74e-83	256.0	COG1064@1|root,COG1064@2|Bacteria,2NP06@2323|unclassified Bacteria	2|Bacteria	S	Alcohol dehydrogenase GroES-like domain	adhA	-	1.1.1.1	ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
k59_203874_1	398767.Glov_2700	1.08e-63	206.0	COG2199@1|root,COG3706@2|Bacteria,1RAKG@1224|Proteobacteria,42QYD@68525|delta/epsilon subdivisions,2WN6A@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS_9
k59_60006_1	649638.Trad_2387	2.14e-52	186.0	COG2199@1|root,COG3850@1|root,COG5278@1|root,COG3706@2|Bacteria,COG3850@2|Bacteria,COG5278@2|Bacteria,1WI95@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	T	TIGRFAM diguanylate cyclase (GGDEF) domain	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,GAF_3,GGDEF,HAMP,HisKA_7TM,PAS_4
k59_67447_1	87626.PTD2_07289	2.68e-25	112.0	COG0642@1|root,COG3614@1|root,COG0642@2|Bacteria,COG2205@2|Bacteria,COG3614@2|Bacteria,1NRP8@1224|Proteobacteria,1SKTW@1236|Gammaproteobacteria,2Q5GD@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	T	PAS domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_3,HATPase_c,HisKA,Hpt,PAS_3,PAS_9,Response_reg
k59_181074_1	504472.Slin_0795	0.000122	50.4	COG3829@1|root,COG4251@1|root,COG3829@2|Bacteria,COG4251@2|Bacteria,4P08P@976|Bacteroidetes,47TG6@768503|Cytophagia	976|Bacteroidetes	T	signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4,PAS_9
k59_44597_1	1121440.AUMA01000010_gene452	3.85e-09	62.8	COG1578@1|root,COG1578@2|Bacteria,1R50K@1224|Proteobacteria,42Q0S@68525|delta/epsilon subdivisions,2WJ5M@28221|Deltaproteobacteria,2M85H@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Protein of unknown function DUF89	-	-	-	-	-	-	-	-	-	-	-	-	DUF89
k59_90669_1	1265505.ATUG01000002_gene1250	7.26e-29	115.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,43BR8@68525|delta/epsilon subdivisions,2X724@28221|Deltaproteobacteria,2MPMS@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Sigma-54 interaction domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Sigma54_activat
k59_120941_1	555779.Dthio_PD1862	9.77e-32	127.0	COG2414@1|root,COG2414@2|Bacteria,1MWBB@1224|Proteobacteria,42NR7@68525|delta/epsilon subdivisions,2WK49@28221|Deltaproteobacteria,2MAH4@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	PFAM Aldehyde ferredoxin oxidoreductase	-	-	1.2.7.5	ko:K03738	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00309	R08571	RC00242	ko00000,ko00001,ko00002,ko01000	-	-	-	AFOR_C,AFOR_N
k59_97956_1	927677.ALVU02000001_gene1927	8.58e-30	123.0	COG2885@1|root,COG2885@2|Bacteria,1G2YF@1117|Cyanobacteria	1117|Cyanobacteria	M	COGs COG2885 Outer membrane protein and related peptidoglycan-associated (lipo)protein	-	-	-	ko:K02557,ko:K03286	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1,1.B.6	-	-	OmpA
k59_83181_1	880072.Desac_0544	4.64e-106	339.0	COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1145@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1145@2|Bacteria,1MVM0@1224|Proteobacteria,42MZ0@68525|delta/epsilon subdivisions,2WJ96@28221|Deltaproteobacteria,2MSJC@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	Pyruvate:ferredoxin oxidoreductase core domain II	por	-	1.2.7.1	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00173,M00307	R01196,R10866	RC00004,RC02742	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	EKR,Fer4_16,Fer4_7,PFOR_II,POR,POR_N,TPP_enzyme_C
k59_90679_1	335543.Sfum_4102	9.03e-84	256.0	COG1181@1|root,COG1181@2|Bacteria,1MUTB@1224|Proteobacteria,42NF2@68525|delta/epsilon subdivisions,2WJ7Q@28221|Deltaproteobacteria,2MQE4@213462|Syntrophobacterales	28221|Deltaproteobacteria	F	Belongs to the D-alanine--D-alanine ligase family	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
k59_143991_2	697282.Mettu_3252	1.88e-18	85.5	COG1216@1|root,COG1216@2|Bacteria,1QVEM@1224|Proteobacteria,1T2CN@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Glycosyl Transferase	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
k59_173945_1	76114.ebA2038	3.1e-54	190.0	COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,2VGZU@28216|Betaproteobacteria,2KY7I@206389|Rhodocyclales	1224|Proteobacteria	I	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain	-	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N,ECH_1
k59_97961_1	1499967.BAYZ01000048_gene2696	2.76e-77	244.0	COG2230@1|root,COG2230@2|Bacteria	2|Bacteria	M	cyclopropane-fatty-acyl-phospholipid synthase	cfa	-	2.1.1.317,2.1.1.79	ko:K00574,ko:K20238	-	-	-	-	ko00000,ko01000	-	-	iJN746.PP_2734	CMAS
k59_29371_2	1121405.dsmv_1271	1.02e-08	56.6	COG0589@1|root,COG0589@2|Bacteria,1NY54@1224|Proteobacteria	1224|Proteobacteria	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
k59_204433_1	1499967.BAYZ01000005_gene5439	1.14e-05	46.6	COG1410@1|root,COG1410@2|Bacteria	2|Bacteria	E	methionine synthase	metH	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
k59_204433_2	706587.Desti_4771	1.35e-64	211.0	COG0407@1|root,COG0407@2|Bacteria,1R9IN@1224|Proteobacteria,42Q1Q@68525|delta/epsilon subdivisions,2WMDE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	PFAM Uroporphyrinogen decarboxylase (URO-D)	-	-	-	-	-	-	-	-	-	-	-	-	URO-D
k59_6198_1	439235.Dalk_3717	4.5e-40	141.0	COG1192@1|root,COG1192@2|Bacteria,1MV43@1224|Proteobacteria,42MTF@68525|delta/epsilon subdivisions,2WJ6X@28221|Deltaproteobacteria,2MHMY@213118|Desulfobacterales	28221|Deltaproteobacteria	D	PFAM CobQ CobB MinD ParA nucleotide binding domain	soj	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
k59_120956_1	880072.Desac_2370	7.59e-32	122.0	COG0767@1|root,COG0767@2|Bacteria,1MVPN@1224|Proteobacteria,42MG3@68525|delta/epsilon subdivisions,2WKC7@28221|Deltaproteobacteria,2MQ7Q@213462|Syntrophobacterales	28221|Deltaproteobacteria	Q	COGs COG0767 ABC-type transport system involved in resistance to organic solvents permease component	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
k59_196113_1	933262.AXAM01000029_gene2749	4.82e-99	304.0	COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,42M1X@68525|delta/epsilon subdivisions,2WJA2@28221|Deltaproteobacteria,2MHZK@213118|Desulfobacterales	28221|Deltaproteobacteria	EH	TIGRFAM acetolactate synthase, large subunit, biosynthetic type	ilvB	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
k59_6199_1	756067.MicvaDRAFT_3403	2.36e-39	149.0	COG1449@1|root,COG1449@2|Bacteria,1G0BM@1117|Cyanobacteria,1H9KC@1150|Oscillatoriales	1117|Cyanobacteria	G	Belongs to the glycosyl hydrolase 57 family	-	-	-	-	-	-	-	-	-	-	-	-	DUF3536,Glyco_hydro_57
k59_29384_1	880072.Desac_0831	8.71e-81	247.0	COG0685@1|root,COG0685@2|Bacteria,1MXTZ@1224|Proteobacteria,42NTS@68525|delta/epsilon subdivisions,2WK04@28221|Deltaproteobacteria,2MRE6@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	Methylenetetrahydrofolate reductase	-	-	1.5.1.20,2.1.1.10	ko:K00297,ko:K00547	ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523	M00377	R00650,R01224,R07168	RC00003,RC00035,RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	CdhD,MTHFR
k59_29384_2	880072.Desac_0832	1.13e-83	251.0	COG4656@1|root,COG4656@2|Bacteria,1MWAX@1224|Proteobacteria,42NJM@68525|delta/epsilon subdivisions,2WJJB@28221|Deltaproteobacteria,2MRCN@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	Methylene-tetrahydrofolate reductase C terminal	-	-	-	-	-	-	-	-	-	-	-	-	MTHFR_C
k59_106065_1	1121405.dsmv_0557	4.37e-73	238.0	COG0427@1|root,COG0454@1|root,COG0427@2|Bacteria,COG0456@2|Bacteria,1MUGE@1224|Proteobacteria,42MHC@68525|delta/epsilon subdivisions,2WINZ@28221|Deltaproteobacteria,2MJ4K@213118|Desulfobacterales	28221|Deltaproteobacteria	CK	PFAM Acetyl-CoA hydrolase transferase	-	-	-	-	-	-	-	-	-	-	-	-	AcetylCoA_hyd_C,AcetylCoA_hydro,Acetyltransf_1
k59_219226_2	243233.MCA0970	3.56e-15	75.1	COG0524@1|root,COG0524@2|Bacteria,1MWX4@1224|Proteobacteria,1RU49@1236|Gammaproteobacteria,1XETS@135618|Methylococcales	135618|Methylococcales	G	Belongs to the carbohydrate kinase PfkB family	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
k59_165911_1	335543.Sfum_2164	3.85e-143	432.0	COG1480@1|root,COG1480@2|Bacteria,1NCY5@1224|Proteobacteria,42MI9@68525|delta/epsilon subdivisions,2WJI1@28221|Deltaproteobacteria,2MR04@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	7TM-HD extracellular	-	-	-	ko:K07037	-	-	-	-	ko00000	-	-	-	7TM-7TMR_HD,7TMR-HDED,HD
k59_83202_1	439235.Dalk_4523	1.12e-79	255.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,43BR8@68525|delta/epsilon subdivisions,2X724@28221|Deltaproteobacteria,2MPMS@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Sigma-54 interaction domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Sigma54_activat
k59_75267_1	933262.AXAM01000015_gene116	7.88e-44	161.0	COG0728@1|root,COG0728@2|Bacteria,1MUH0@1224|Proteobacteria,42M28@68525|delta/epsilon subdivisions,2WJPF@28221|Deltaproteobacteria,2MIBD@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane	murJ	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
k59_97986_1	570417.WP0972	4.34e-54	184.0	COG3344@1|root,COG3344@2|Bacteria,1MVI1@1224|Proteobacteria,2U1Z0@28211|Alphaproteobacteria,47GRS@766|Rickettsiales	766|Rickettsiales	L	Group II intron, maturase-specific domain	-	-	-	-	-	-	-	-	-	-	-	-	GIIM,RVT_1
k59_219233_1	1121406.JAEX01000019_gene2772	1.2e-55	194.0	COG0341@1|root,COG0342@1|root,COG0341@2|Bacteria,COG0342@2|Bacteria,1MV5U@1224|Proteobacteria,42M6V@68525|delta/epsilon subdivisions,2WJCI@28221|Deltaproteobacteria,2M865@213115|Desulfovibrionales	28221|Deltaproteobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
k59_158871_1	177437.HRM2_16600	1.07e-113	342.0	COG1894@1|root,COG1894@2|Bacteria,1MV8F@1224|Proteobacteria,42N6N@68525|delta/epsilon subdivisions,2WJ1W@28221|Deltaproteobacteria,2MJ8N@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Respiratory-chain NADH dehydrogenase domain 51 kDa subunit	-	-	1.12.1.3,1.6.5.2,1.6.5.3	ko:K00124,ko:K00335,ko:K00355,ko:K18331	ko00130,ko00190,ko00630,ko00680,ko01100,ko01110,ko01120,ko01200,ko05200,ko05225,ko05418,map00130,map00190,map00630,map00680,map01100,map01110,map01120,map01200,map05200,map05225,map05418	M00144	R00519,R02964,R03643,R03816,R11945	RC00061,RC00819,RC02796	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx,Complex1_51K,Fer4,NADH_4Fe-4S,SLBB
k59_22029_2	933262.AXAM01000015_gene115	7.3e-13	68.2	COG0436@1|root,COG0436@2|Bacteria,1QW10@1224|Proteobacteria,42MQA@68525|delta/epsilon subdivisions,2WJDK@28221|Deltaproteobacteria,2MJ7D@213118|Desulfobacterales	28221|Deltaproteobacteria	E	PFAM aminotransferase class I and II	bamJ	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
k59_212257_1	497965.Cyan7822_1250	1.61e-80	248.0	COG0667@1|root,COG0667@2|Bacteria,1G1J4@1117|Cyanobacteria,3KG02@43988|Cyanothece	1117|Cyanobacteria	C	PFAM aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
k59_44630_1	264732.Moth_2229	1.03e-128	375.0	COG2801@1|root,COG2801@2|Bacteria,1TRNK@1239|Firmicutes,24B7I@186801|Clostridia,42G6M@68295|Thermoanaerobacterales	186801|Clostridia	L	HTH-like domain	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,HTH_Tnp_1,rve,rve_3
k59_44630_2	679200.HMPREF9333_02169	3.39e-16	74.7	COG2963@1|root,COG2963@2|Bacteria,1VCUH@1239|Firmicutes,24NX4@186801|Clostridia	186801|Clostridia	L	Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Tnp_1
k59_6229_1	207559.Dde_3718	8.31e-66	225.0	COG3850@1|root,COG4191@1|root,COG3850@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42NFY@68525|delta/epsilon subdivisions,2WJKV@28221|Deltaproteobacteria,2M7VM@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	PFAM ATP-binding region ATPase domain protein	-	-	2.7.13.3	ko:K02482,ko:K10819	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS_4,PAS_9
k59_204478_2	1232437.KL662006_gene4387	1.79e-38	130.0	COG2208@1|root,COG2208@2|Bacteria	2|Bacteria	T	phosphoserine phosphatase activity	pkn5	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	AAA_16,GAF,HAMP,Pkinase,Response_reg,SpoIIE,dCache_1
k59_83216_1	335543.Sfum_3548	5.77e-115	343.0	COG0508@1|root,COG0508@2|Bacteria,1MUJD@1224|Proteobacteria,42N18@68525|delta/epsilon subdivisions,2WJSK@28221|Deltaproteobacteria,2MRUP@213462|Syntrophobacterales	28221|Deltaproteobacteria	I	2-oxoacid dehydrogenases acyltransferase (catalytic domain)	sucB	-	2.3.1.12,2.3.1.61	ko:K00627,ko:K00658	ko00010,ko00020,ko00310,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00310,map00620,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032,M00307	R00209,R02569,R02570,R02571,R08549	RC00004,RC02727,RC02742,RC02833,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2766	2-oxoacid_dh,Biotin_lipoyl,E3_binding
k59_109073_1	207559.Dde_1479	1.93e-55	190.0	COG1253@1|root,COG1253@2|Bacteria,1MWT3@1224|Proteobacteria,42N45@68525|delta/epsilon subdivisions,2WKUD@28221|Deltaproteobacteria,2M8FS@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	CBS domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CBS,DUF21
k59_238194_1	1121405.dsmv_2695	1.95e-71	231.0	COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,42M88@68525|delta/epsilon subdivisions,2WIZI@28221|Deltaproteobacteria,2MJ2S@213118|Desulfobacterales	28221|Deltaproteobacteria	T	PFAM sigma-54 factor interaction domain-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,PAS_9,Sigma54_activat
k59_132604_1	481448.Minf_2442	9.71e-28	117.0	COG0577@1|root,COG0577@2|Bacteria,46SI8@74201|Verrucomicrobia,37GGE@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	V	MacB-like periplasmic core domain	salY	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
k59_94570_1	1304885.AUEY01000094_gene3538	2.47e-97	302.0	COG2070@1|root,COG2070@2|Bacteria,1MWMI@1224|Proteobacteria,42P2I@68525|delta/epsilon subdivisions,2WK0M@28221|Deltaproteobacteria,2MIJJ@213118|Desulfobacterales	28221|Deltaproteobacteria	S	TIGRFAM PfaD family protein	-	-	-	-	-	-	-	-	-	-	-	-	NMO
k59_26083_1	123214.PERMA_0105	4.29e-55	189.0	COG1030@1|root,COG1030@2|Bacteria,2G4F0@200783|Aquificae	200783|Aquificae	O	NfeD-like C-terminal, partner-binding	nfeD	-	-	ko:K07403	-	-	-	-	ko00000	-	-	-	CLP_protease,NfeD
k59_215732_1	1385935.N836_09375	6.38e-14	72.4	COG3324@1|root,COG3324@2|Bacteria,1GA6T@1117|Cyanobacteria	1117|Cyanobacteria	S	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	ko:K06996	-	-	-	-	ko00000	-	-	-	Glyoxalase
k59_71838_1	1312959.KI914677_gene2203	7.23e-11	66.6	COG2984@1|root,COG2984@2|Bacteria,2GKNV@201174|Actinobacteria,1W7KU@1268|Micrococcaceae	201174|Actinobacteria	S	sugar ABC transporter, substrate-binding protein	-	-	-	ko:K01989	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_sub_bind
k59_177738_1	1459636.NTE_00355	1.35e-68	225.0	COG0459@1|root,arCOG01257@2157|Archaea,41SDG@651137|Thaumarchaeota	2157|Archaea	O	PFAM TCP-1 cpn60 chaperonin family	thsA	GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0044183,GO:0051082,GO:0061077	-	ko:K22447	-	-	-	-	ko00000,ko03110	-	-	-	Cpn60_TCP1
k59_86785_1	439235.Dalk_4002	2.17e-89	276.0	COG0232@1|root,COG0232@2|Bacteria,1R6QQ@1224|Proteobacteria,42M0H@68525|delta/epsilon subdivisions,2WJ33@28221|Deltaproteobacteria,2MHN1@213118|Desulfobacterales	28221|Deltaproteobacteria	F	SMART metal-dependent phosphohydrolase HD region	-	-	3.1.5.1	ko:K01129	ko00230,map00230	-	R01856	RC00017	ko00000,ko00001,ko01000	-	-	-	HD,HD_assoc
k59_86785_2	690850.Desaf_3811	1.81e-06	50.4	COG0457@1|root,COG1944@1|root,COG0457@2|Bacteria,COG1944@2|Bacteria,1MV7K@1224|Proteobacteria,42N4B@68525|delta/epsilon subdivisions,2WJ34@28221|Deltaproteobacteria,2M7ZT@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	repeat-containing protein	-	-	-	ko:K09136	-	-	-	-	ko00000,ko03009	-	-	-	TPR_1,TPR_16,TPR_2,TPR_8,YcaO
k59_170389_1	335543.Sfum_1265	3.05e-102	320.0	COG0037@1|root,COG0037@2|Bacteria,1MU85@1224|Proteobacteria,42NF0@68525|delta/epsilon subdivisions,2WIJK@28221|Deltaproteobacteria,2MQFN@213462|Syntrophobacterales	28221|Deltaproteobacteria	D	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	6.3.4.19	ko:K04075	-	-	R09597	RC02633,RC02634	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3,TilS,TilS_C
k59_56874_1	1444309.JAQG01000078_gene4110	6.35e-27	111.0	COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,4IS6U@91061|Bacilli,277BY@186822|Paenibacillaceae	91061|Bacilli	T	His Kinase A (phosphoacceptor) domain	yclK	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
k59_11410_1	903818.KI912268_gene2028	8.47e-11	60.5	COG1633@1|root,COG1633@2|Bacteria	2|Bacteria	S	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)	-	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
k59_11410_2	880072.Desac_2166	1.13e-38	143.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,1NBSJ@1224|Proteobacteria,42MXV@68525|delta/epsilon subdivisions,2WIIT@28221|Deltaproteobacteria,2MRG4@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain	porA	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR,POR_N,Transketolase_C
k59_140257_1	521460.Athe_1248	2.12e-27	113.0	COG0165@1|root,COG0165@2|Bacteria,1TNZ6@1239|Firmicutes,2489H@186801|Clostridia,42F08@68295|Thermoanaerobacterales	186801|Clostridia	E	TIGRFAM argininosuccinate lyase	argH	-	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ASL_C2,Lyase_1
k59_231269_1	933262.AXAM01000083_gene762	3.75e-36	132.0	COG0426@1|root,COG0426@2|Bacteria,1R4UD@1224|Proteobacteria,43AF5@68525|delta/epsilon subdivisions,2X5UW@28221|Deltaproteobacteria,2MPG5@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Flavodoxin	roo	-	-	-	-	-	-	-	-	-	-	-	Flavodoxin_1,Lactamase_B,Lactamase_B_2
k59_231269_2	693979.Bache_0962	1.64e-24	92.4	COG1773@1|root,COG1773@2|Bacteria,4NHF0@976|Bacteroidetes,2FUN6@200643|Bacteroidia,4AS7V@815|Bacteroidaceae	976|Bacteroidetes	C	Psort location Cytoplasmic, score	rubR	-	-	-	-	-	-	-	-	-	-	-	Rubredoxin
k59_125218_1	216596.RL0061	8.37e-36	134.0	COG0366@1|root,COG0366@2|Bacteria,1PDXT@1224|Proteobacteria,2UQIK@28211|Alphaproteobacteria,4BIGR@82115|Rhizobiaceae	28211|Alphaproteobacteria	G	alpha amylase, catalytic region	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase
k59_125218_2	99598.Cal7507_5856	1.12e-35	137.0	COG0296@1|root,COG0296@2|Bacteria,1G1IW@1117|Cyanobacteria,1HJD9@1161|Nostocales	1117|Cyanobacteria	G	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position	glgB	-	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	iJN678.glgB	Alpha-amylase,Alpha-amylase_C,CBM_48
k59_86792_1	323097.Nham_0803	6.62e-17	87.0	COG0863@1|root,COG1475@1|root,COG0863@2|Bacteria,COG1475@2|Bacteria,1MVH7@1224|Proteobacteria,2TRNA@28211|Alphaproteobacteria,3JW7V@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	KL	DNA methylase	-	-	-	-	-	-	-	-	-	-	-	-	N6_N4_Mtase,ParBc
k59_3164_1	485915.Dret_0276	5.12e-56	188.0	COG2309@1|root,COG2309@2|Bacteria,1MW2Y@1224|Proteobacteria,42P6P@68525|delta/epsilon subdivisions,2WJF8@28221|Deltaproteobacteria,2M90N@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	PFAM Peptidase M29, aminopeptidase II	-	-	-	ko:K19689	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M29
k59_185995_1	439235.Dalk_1467	1.07e-73	239.0	COG1960@1|root,COG1960@2|Bacteria,1MU20@1224|Proteobacteria	1224|Proteobacteria	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_C,Acyl-CoA_dh_M,Acyl-CoA_dh_N,AcylCoA_DH_N
k59_192927_1	1034807.FBFL15_2404	9.99e-37	135.0	COG1044@1|root,COG1044@2|Bacteria,4NH6I@976|Bacteroidetes,1HXDW@117743|Flavobacteriia,2NU1K@237|Flavobacterium	976|Bacteroidetes	M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	-	-	2.3.1.191	ko:K02536	ko00540,ko01100,map00540,map01100	M00060	R04550	RC00039,RC00166	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hexapep,Hexapep_2,LpxD
k59_200781_1	316067.Geob_1232	3.47e-196	565.0	COG0556@1|root,COG0556@2|Bacteria,1MUFK@1224|Proteobacteria,42MFA@68525|delta/epsilon subdivisions,2WJ20@28221|Deltaproteobacteria,43U9W@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
k59_185999_1	443143.GM18_3025	7.81e-29	119.0	COG3501@1|root,COG3501@2|Bacteria,1MU7Q@1224|Proteobacteria,42Q4M@68525|delta/epsilon subdivisions,2WKZN@28221|Deltaproteobacteria,43UM5@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Phage late control gene D protein (GPD)	tssI	-	-	ko:K11904	ko03070,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	Gp5_C,Phage_GPD
k59_125225_1	338963.Pcar_1001	1.69e-213	602.0	COG1109@1|root,COG1109@2|Bacteria,1MU24@1224|Proteobacteria,42M6I@68525|delta/epsilon subdivisions,2WJTV@28221|Deltaproteobacteria,43T4H@69541|Desulfuromonadales	28221|Deltaproteobacteria	G	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate	glmM	-	5.4.2.10	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	-	R02060	RC00408	ko00000,ko00001,ko01000	-	-	iAF987.Gmet_1886	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
k59_116962_1	933262.AXAM01000002_gene544	3.17e-41	143.0	COG0714@1|root,COG0714@2|Bacteria,1MXIW@1224|Proteobacteria,42MX4@68525|delta/epsilon subdivisions,2WKVB@28221|Deltaproteobacteria,2MHKN@213118|Desulfobacterales	28221|Deltaproteobacteria	S	ATPase associated with various cellular activities AAA_5	-	-	-	ko:K04748	-	-	R00294	RC02794	ko00000	3.D.4.10	-	-	AAA_5,CbbQ_C
k59_11432_1	192952.MM_1645	3.3e-25	110.0	COG2006@1|root,arCOG02447@2157|Archaea	2157|Archaea	S	4Fe-4S ferredoxin iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF362
k59_26106_1	525897.Dbac_2634	1.95e-79	254.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,42M51@68525|delta/epsilon subdivisions,2WIPP@28221|Deltaproteobacteria,2M915@213115|Desulfovibrionales	28221|Deltaproteobacteria	NU	PFAM Type II secretion system protein E	epsE	-	-	ko:K02454,ko:K02652	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSE,T2SSE_N
k59_109699_1	1121405.dsmv_0691	6.98e-124	369.0	COG5421@1|root,COG5421@2|Bacteria,1R3NX@1224|Proteobacteria,42QDV@68525|delta/epsilon subdivisions,2WIRQ@28221|Deltaproteobacteria,2MN1S@213118|Desulfobacterales	68525|delta/epsilon subdivisions	L	PFAM transposase IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
k59_34035_1	1168067.JAGP01000001_gene2036	2.92e-64	208.0	COG1162@1|root,COG1162@2|Bacteria,1MUEF@1224|Proteobacteria,1RMMB@1236|Gammaproteobacteria,461YZ@72273|Thiotrichales	72273|Thiotrichales	S	Pfam:DUF258	-	-	-	-	-	-	-	-	-	-	-	-	RsgA_GTPase
k59_125226_2	1128421.JAGA01000002_gene1033	1.69e-39	143.0	COG0275@1|root,COG0275@2|Bacteria,2NP8Y@2323|unclassified Bacteria	2|Bacteria	J	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH	-	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
k59_140276_1	1123376.AUIU01000004_gene1175	2.81e-14	75.9	COG3385@1|root,COG3385@2|Bacteria,3J1AD@40117|Nitrospirae	40117|Nitrospirae	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_4
k59_132650_1	1262914.BN533_00197	6.54e-12	68.6	COG3740@1|root,COG3740@2|Bacteria,1VWCZ@1239|Firmicutes	1239|Firmicutes	S	Phage prohead protease, HK97 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S78
k59_192929_1	525909.Afer_0320	0.000453	42.7	COG0074@1|root,COG0074@2|Bacteria,2GK00@201174|Actinobacteria,4CMSK@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit	sucD	-	6.2.1.5	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_binding,Ligase_CoA
k59_192929_2	161156.JQKW01000010_gene291	2.28e-34	126.0	COG0703@1|root,COG0703@2|Bacteria,2GI06@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	E	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate	aroK	-	2.7.1.71	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	SKI
k59_48954_2	335543.Sfum_1392	4.1e-12	65.1	COG0655@1|root,COG0655@2|Bacteria,1RCJ8@1224|Proteobacteria,42QQT@68525|delta/epsilon subdivisions,2WMRW@28221|Deltaproteobacteria,2MQYY@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	PFAM NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
k59_11437_1	177437.HRM2_22360	5.12e-80	256.0	COG0374@1|root,COG0374@2|Bacteria,1MWFJ@1224|Proteobacteria,42M4S@68525|delta/epsilon subdivisions,2WJQS@28221|Deltaproteobacteria,2MI12@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Belongs to the NiFe NiFeSe hydrogenase large subunit family	hynA	GO:0005575,GO:0005623,GO:0042597,GO:0044464	1.12.2.1,1.12.5.1,1.12.7.2,1.12.99.6	ko:K00437,ko:K00533,ko:K05922,ko:K06281	ko00633,ko01120,map00633,map01120	-	R00019,R08034	RC00250	ko00000,ko00001,ko01000	-	-	-	NiFeSe_Hases
k59_3171_2	237368.SCABRO_02795	5.72e-20	96.7	COG0784@1|root,COG3290@1|root,COG4191@1|root,COG0784@2|Bacteria,COG3290@2|Bacteria,COG4191@2|Bacteria,2IYAX@203682|Planctomycetes	203682|Planctomycetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,PAS,PAS_9,Response_reg
k59_231296_2	234267.Acid_6122	9.18e-58	188.0	2DB88@1|root,2Z7QT@2|Bacteria,3Y61J@57723|Acidobacteria	57723|Acidobacteria	S	Domain of unknown function (DUF4338)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4338
k59_64220_1	1121438.JNJA01000001_gene2510	6.95e-42	151.0	COG1639@1|root,COG1639@2|Bacteria,1RAH3@1224|Proteobacteria,42PRF@68525|delta/epsilon subdivisions,2WMIN@28221|Deltaproteobacteria,2M912@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	PFAM Metal-dependent hydrolase HDOD	-	-	-	-	-	-	-	-	-	-	-	-	HDOD
k59_132655_2	397291.C804_04932	2.37e-45	167.0	COG2801@1|root,COG2801@2|Bacteria,1TT3E@1239|Firmicutes,24BA2@186801|Clostridia,27KHK@186928|unclassified Lachnospiraceae	186801|Clostridia	L	DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS240
k59_186009_1	1121405.dsmv_0963	1.37e-105	316.0	COG0341@1|root,COG0341@2|Bacteria,1MU74@1224|Proteobacteria,42M2H@68525|delta/epsilon subdivisions,2WJ8I@28221|Deltaproteobacteria,2MI34@213118|Desulfobacterales	28221|Deltaproteobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secF	-	-	ko:K03074	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
k59_132661_1	96561.Dole_3026	4.63e-39	148.0	COG0515@1|root,COG0515@2|Bacteria,1R8C8@1224|Proteobacteria,42Q9Y@68525|delta/epsilon subdivisions,2WME3@28221|Deltaproteobacteria,2MJ3C@213118|Desulfobacterales	28221|Deltaproteobacteria	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
k59_170436_1	682795.AciX8_1687	1.15e-35	133.0	COG0482@1|root,COG0482@2|Bacteria,3Y2JX@57723|Acidobacteria,2JHKV@204432|Acidobacteriia	204432|Acidobacteriia	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
k59_170436_2	1120972.AUMH01000001_gene1252	5e-34	131.0	COG0621@1|root,COG0621@2|Bacteria,1TPBR@1239|Firmicutes,4HBYZ@91061|Bacilli,2795D@186823|Alicyclobacillaceae	91061|Bacilli	J	Uncharacterized protein family UPF0004	yqeV	GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016782,GO:0034470,GO:0034641,GO:0034660,GO:0035596,GO:0035598,GO:0035600,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0050497,GO:0071704,GO:0090304,GO:1901360	2.8.4.5	ko:K18707	-	-	R10649	RC00003,RC03221	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
k59_155486_1	1121405.dsmv_2161	4.1e-112	337.0	COG0459@1|root,COG0459@2|Bacteria,1MURR@1224|Proteobacteria,42M52@68525|delta/epsilon subdivisions,2WIRK@28221|Deltaproteobacteria,2MHPV@213118|Desulfobacterales	28221|Deltaproteobacteria	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	-	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
k59_215774_1	756272.Plabr_1743	2.86e-15	72.4	COG3157@1|root,COG3157@2|Bacteria,2J0G0@203682|Planctomycetes	203682|Planctomycetes	S	TIGRFAM type VI secretion system effector, Hcp1 family	-	-	-	ko:K11903	ko02025,ko03070,map02025,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko02044	-	-	-	T6SS_HCP
k59_71899_1	519989.ECTPHS_14156	6.75e-51	166.0	COG1943@1|root,COG1943@2|Bacteria,1MX19@1224|Proteobacteria,1RSJY@1236|Gammaproteobacteria,1WY4B@135613|Chromatiales	135613|Chromatiales	L	PFAM Transposase	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
k59_208618_2	216596.RL0355	3.88e-19	85.9	COG1741@1|root,COG1741@2|Bacteria,1MWIP@1224|Proteobacteria,2TRHR@28211|Alphaproteobacteria,4BBDC@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Belongs to the pirin family	yhhW	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin,Pirin_C
k59_155487_1	1121405.dsmv_2727	6.69e-81	261.0	COG0466@1|root,COG0466@2|Bacteria,1MUV2@1224|Proteobacteria,42M9W@68525|delta/epsilon subdivisions,2WJ29@28221|Deltaproteobacteria,2MHRD@213118|Desulfobacterales	28221|Deltaproteobacteria	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	-	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
k59_109730_1	1121439.dsat_0673	2.73e-14	72.4	COG2427@1|root,COG2427@2|Bacteria,1P6AT@1224|Proteobacteria,43355@68525|delta/epsilon subdivisions,2WXWE@28221|Deltaproteobacteria,2MBQA@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF1641)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1641
k59_18567_1	933262.AXAM01000053_gene2714	2.41e-118	350.0	COG0045@1|root,COG0045@2|Bacteria,1MVCE@1224|Proteobacteria,42M5K@68525|delta/epsilon subdivisions,2WJTS@28221|Deltaproteobacteria,2MHZ2@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit	sucC	-	6.2.1.5	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2261	ATP-grasp_2,Ligase_CoA
k59_140299_1	1121405.dsmv_1656	2.5e-31	116.0	COG2010@1|root,COG2010@2|Bacteria,1QSQ1@1224|Proteobacteria,437J9@68525|delta/epsilon subdivisions,2X2T9@28221|Deltaproteobacteria,2MNXV@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
k59_140299_2	1121405.dsmv_1657	1.45e-25	96.7	298U3@1|root,2ZVYA@2|Bacteria,1P6XQ@1224|Proteobacteria,432W5@68525|delta/epsilon subdivisions,2WXGU@28221|Deltaproteobacteria,2MP3E@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_102405_1	1232437.KL662031_gene2606	2.02e-27	102.0	COG1837@1|root,COG1837@2|Bacteria,1N7IX@1224|Proteobacteria,42TXI@68525|delta/epsilon subdivisions,2WQBS@28221|Deltaproteobacteria,2MKI6@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Belongs to the UPF0109 family	-	-	-	ko:K06960	-	-	-	-	ko00000	-	-	-	KH_4
k59_86837_1	207559.Dde_3718	7.37e-06	53.5	COG3850@1|root,COG4191@1|root,COG3850@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42NFY@68525|delta/epsilon subdivisions,2WJKV@28221|Deltaproteobacteria,2M7VM@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	PFAM ATP-binding region ATPase domain protein	-	-	2.7.13.3	ko:K02482,ko:K10819	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS_4,PAS_9
k59_26122_1	1123392.AQWL01000002_gene2032	5.19e-28	109.0	COG0526@1|root,COG0526@2|Bacteria,1MZ36@1224|Proteobacteria,2VWK8@28216|Betaproteobacteria,1KT4G@119069|Hydrogenophilales	119069|Hydrogenophilales	CO	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
k59_71911_1	690850.Desaf_0246	2.38e-12	66.2	COG1246@1|root,COG1246@2|Bacteria,1R0RF@1224|Proteobacteria,43D0Y@68525|delta/epsilon subdivisions,2X88U@28221|Deltaproteobacteria,2MHDF@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	TIGRFAM C_GCAxxG_C_C family protein	-	-	-	-	-	-	-	-	-	-	-	-	C_GCAxxG_C_C
k59_125250_1	933262.AXAM01000003_gene2802	5.05e-79	260.0	COG0517@1|root,COG0617@1|root,COG0618@1|root,COG0517@2|Bacteria,COG0617@2|Bacteria,COG0618@2|Bacteria,1MU2X@1224|Proteobacteria,42MJJ@68525|delta/epsilon subdivisions,2WJBN@28221|Deltaproteobacteria,2MI4C@213118|Desulfobacterales	28221|Deltaproteobacteria	J	CBS domain	ccaA	-	2.7.7.72	ko:K00974	ko03013,map03013	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016	-	-	-	CBS,DHH,DHHA1,PolyA_pol,PolyA_pol_RNAbd
k59_208630_1	1123393.KB891331_gene2937	6.02e-19	83.6	COG3658@1|root,COG3658@2|Bacteria,1N28F@1224|Proteobacteria,2VU1H@28216|Betaproteobacteria,1KSP1@119069|Hydrogenophilales	119069|Hydrogenophilales	C	Dihaem cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	DHC
k59_208630_2	861299.J421_1627	1.9e-24	98.6	COG1720@1|root,COG1720@2|Bacteria	2|Bacteria	S	tRNA m6t6A37 methyltransferase activity	tsaA	-	-	-	-	-	-	-	-	-	-	-	UPF0066
k59_231327_1	96561.Dole_0502	2.36e-41	139.0	COG2893@1|root,COG2893@2|Bacteria,1RHH7@1224|Proteobacteria,42SST@68525|delta/epsilon subdivisions,2WPWN@28221|Deltaproteobacteria,2MK4F@213118|Desulfobacterales	28221|Deltaproteobacteria	G	PFAM PTS system fructose subfamily IIA component	-	-	2.7.1.191	ko:K02793	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	M00276	R02630	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.6.1	-	-	EIIA-man
k59_215787_1	1265505.ATUG01000001_gene3468	3.94e-79	249.0	COG5598@1|root,COG5598@2|Bacteria,1MWJN@1224|Proteobacteria,42Q8R@68525|delta/epsilon subdivisions,2WMDK@28221|Deltaproteobacteria,2MJEG@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Trimethylamine methyltransferase	-	-	2.1.1.250	ko:K14083	ko00680,ko01120,ko01200,map00680,map01120,map01200	M00563	R09124,R10016	RC00035,RC00732,RC01144,RC02984	ko00000,ko00001,ko00002,ko01000	-	-	-	MTTB
k59_67119_1	439235.Dalk_1883	2.1e-85	273.0	COG0457@1|root,COG0457@2|Bacteria,1RKQQ@1224|Proteobacteria,42T9T@68525|delta/epsilon subdivisions,2WPQ0@28221|Deltaproteobacteria,2MN67@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2,TPR_16,TPR_2,TPR_8
k59_52003_2	1049564.TevJSym_cc00010	5.88e-40	145.0	COG1075@1|root,COG1075@2|Bacteria,1R5PK@1224|Proteobacteria,1RP0G@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	acetyltransferases and hydrolases with the alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
k59_113170_1	1499967.BAYZ01000026_gene1558	2.42e-123	371.0	COG0376@1|root,COG0376@2|Bacteria,2NQNQ@2323|unclassified Bacteria	2|Bacteria	P	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity	katG	GO:0000302,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016684,GO:0016999,GO:0017001,GO:0017144,GO:0020037,GO:0033554,GO:0034599,GO:0034614,GO:0035690,GO:0042221,GO:0042493,GO:0042542,GO:0042737,GO:0042743,GO:0042744,GO:0044237,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0046906,GO:0048037,GO:0050896,GO:0051186,GO:0051187,GO:0051716,GO:0055114,GO:0070301,GO:0070887,GO:0071236,GO:0072593,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901363,GO:1901700,GO:1901701,GO:1990748	1.11.1.21	ko:K03782	ko00360,ko00380,ko00940,ko00983,ko01100,ko01110,map00360,map00380,map00940,map00983,map01100,map01110	-	R00602,R00698,R02596,R02670,R03919,R04007,R07443,R11906	RC00034,RC00213,RC00767,RC02141	ko00000,ko00001,ko01000	-	-	-	peroxidase
k59_44315_1	1202962.KB907154_gene751	5.98e-10	68.9	29I5E@1|root,3052G@2|Bacteria,1QR7E@1224|Proteobacteria,1SMYW@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Flagellar assembly protein T, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	FlgT_N
k59_226546_2	177437.HRM2_32920	3.11e-33	117.0	COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,42V0K@68525|delta/epsilon subdivisions,2WR92@28221|Deltaproteobacteria,2MKYU@213118|Desulfobacterales	28221|Deltaproteobacteria	K	PFAM Cold-shock	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
k59_226546_3	380358.XALC_2189	2.6e-17	80.5	COG1272@1|root,COG1272@2|Bacteria,1PGRH@1224|Proteobacteria,1RR4R@1236|Gammaproteobacteria,1X3JH@135614|Xanthomonadales	135614|Xanthomonadales	S	hemolysin III	hly3	-	-	ko:K11068	-	-	-	-	ko00000,ko02042	-	-	-	HlyIII
k59_241529_1	1042877.GQS_00445	3.09e-71	218.0	COG1720@1|root,arCOG00761@2157|Archaea,2XY3D@28890|Euryarchaeota,2440R@183968|Thermococci	183968|Thermococci	S	Uncharacterised protein family UPF0066	-	-	-	-	-	-	-	-	-	-	-	-	UPF0066
k59_165612_1	944480.ATUV01000002_gene311	1.3e-60	203.0	COG1012@1|root,COG1012@2|Bacteria,1QWN5@1224|Proteobacteria,43BT3@68525|delta/epsilon subdivisions,2X73T@28221|Deltaproteobacteria,2M6JC@213113|Desulfurellales	28221|Deltaproteobacteria	C	Aldehyde dehydrogenase family	pruA	-	1.2.1.88	ko:K00294	ko00250,ko00330,ko01100,map00250,map00330,map01100	-	R00245,R00707,R00708,R04444,R04445,R05051	RC00080,RC00216,RC00242,RC00255	ko00000,ko00001,ko01000	-	-	-	Aldedh
k59_234773_1	1121403.AUCV01000054_gene2598	9.74e-75	228.0	COG2220@1|root,COG2220@2|Bacteria,1PFZZ@1224|Proteobacteria,42SXY@68525|delta/epsilon subdivisions,2WPFM@28221|Deltaproteobacteria,2MMG4@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_3
k59_234773_2	243231.GSU2429	3.62e-13	69.7	COG0760@1|root,COG0760@2|Bacteria,1MZDK@1224|Proteobacteria,42RVN@68525|delta/epsilon subdivisions,2WNJW@28221|Deltaproteobacteria,43SP4@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	SurA N-terminal domain	-	-	5.2.1.8	ko:K03769	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N_3
k59_120359_1	96561.Dole_0367	5.38e-24	100.0	COG0021@1|root,COG0021@2|Bacteria,1MUEY@1224|Proteobacteria,42M80@68525|delta/epsilon subdivisions,2WINJ@28221|Deltaproteobacteria,2MHY9@213118|Desulfobacterales	28221|Deltaproteobacteria	G	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate	tkt	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
k59_120359_2	1121405.dsmv_0317	2.7e-21	90.1	COG1032@1|root,COG1032@2|Bacteria,1P9J0@1224|Proteobacteria,42MWG@68525|delta/epsilon subdivisions,2WIV5@28221|Deltaproteobacteria,2MI1A@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM Radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
k59_67132_1	1501230.ET33_33920	2.31e-05	53.1	COG0477@1|root,COG2814@2|Bacteria,1TQHD@1239|Firmicutes,4HBCZ@91061|Bacilli,26QDE@186822|Paenibacillaceae	91061|Bacilli	EGP	major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_1_like,MFS_3,Sugar_tr
k59_211960_1	933262.AXAM01000011_gene1763	2.47e-26	112.0	COG4191@1|root,COG4191@2|Bacteria,1QUWB@1224|Proteobacteria,42ZJA@68525|delta/epsilon subdivisions,2WV3K@28221|Deltaproteobacteria,2MNAU@213118|Desulfobacterales	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,Response_reg
k59_218906_1	589865.DaAHT2_1704	3.92e-43	145.0	COG1734@1|root,COG1734@2|Bacteria,1RD08@1224|Proteobacteria,42RVK@68525|delta/epsilon subdivisions,2WNNA@28221|Deltaproteobacteria,2MJSM@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters	dksA	-	-	ko:K06204	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000,ko03009,ko03021	-	-	-	zf-dskA_traR
k59_218906_2	1218173.BALCAV_0211195	1.51e-17	84.0	COG0613@1|root,COG0613@2|Bacteria,1TPI5@1239|Firmicutes,4HB6B@91061|Bacilli,1ZDNY@1386|Bacillus	91061|Bacilli	S	DNA polymerase alpha chain like domain	-	-	3.1.3.97	ko:K07053	-	-	R00188,R11188	RC00078	ko00000,ko01000	-	-	-	PHP
k59_82916_1	880072.Desac_1216	6.69e-128	378.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WJKZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Response regulator receiver	-	-	-	ko:K07713	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
k59_60262_1	228405.HNE_3446	1.97e-87	270.0	COG3547@1|root,COG3547@2|Bacteria,1MXKJ@1224|Proteobacteria,2U2G6@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	transposase IS116 IS110 IS902 family protein	-	-	-	ko:K07486	-	-	-	-	ko00000	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_150429_1	314345.SPV1_07004	1.31e-41	156.0	COG0574@1|root,COG0574@2|Bacteria,1P35R@1224|Proteobacteria	1224|Proteobacteria	G	Pyruvate phosphate dikinase	-	-	-	-	-	-	-	-	-	-	-	-	LTD,PPDK_N
k59_241539_1	96561.Dole_3163	1.68e-90	278.0	COG0123@1|root,COG0123@2|Bacteria,1MU7P@1224|Proteobacteria,42MY3@68525|delta/epsilon subdivisions,2WJEF@28221|Deltaproteobacteria,2MI47@213118|Desulfobacterales	28221|Deltaproteobacteria	BQ	PFAM Histone deacetylase	-	-	-	ko:K04768	-	-	-	-	ko00000	-	-	-	Hist_deacetyl
k59_120382_1	555779.Dthio_PD3532	2.38e-61	207.0	COG5421@1|root,COG5421@2|Bacteria,1R7NE@1224|Proteobacteria,42M25@68525|delta/epsilon subdivisions,2WKHV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	IMG reference gene	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
k59_29120_1	1121405.dsmv_2653	1.86e-78	243.0	COG3335@1|root,COG3335@2|Bacteria,1MW8A@1224|Proteobacteria,42RGI@68525|delta/epsilon subdivisions,2WNGP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,HTH_28,HTH_33
k59_21706_1	714943.Mucpa_5776	3.14e-47	174.0	COG0642@1|root,COG3292@1|root,COG0642@2|Bacteria,COG2205@2|Bacteria,COG3292@2|Bacteria,4NDXU@976|Bacteroidetes,1IRJZ@117747|Sphingobacteriia	976|Bacteroidetes	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISM_7TM,GAF,HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Reg_prop,Response_reg,Y_Y_Y
k59_113193_1	335543.Sfum_1549	6.8e-122	384.0	COG0085@1|root,COG0085@2|Bacteria,1MUC4@1224|Proteobacteria,43DMZ@68525|delta/epsilon subdivisions,2WIW5@28221|Deltaproteobacteria,2MR0B@213462|Syntrophobacterales	28221|Deltaproteobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
k59_173690_1	1304885.AUEY01000046_gene9	7.33e-125	374.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,42M51@68525|delta/epsilon subdivisions,2WIVD@28221|Deltaproteobacteria,2MHZ9@213118|Desulfobacterales	28221|Deltaproteobacteria	NU	type II secretion system	pulE-3	-	-	ko:K02454	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSE,T2SSE_N
k59_211989_1	335543.Sfum_3317	1.75e-47	166.0	COG0477@1|root,COG2814@2|Bacteria,1MU1I@1224|Proteobacteria,42KZU@68525|delta/epsilon subdivisions,2WJ6T@28221|Deltaproteobacteria,2MSKS@213462|Syntrophobacterales	28221|Deltaproteobacteria	P	PFAM major facilitator superfamily MFS_1	-	-	-	ko:K03446	-	M00701	-	-	ko00000,ko00002,ko02000	2.A.1.3	-	-	MFS_1
k59_211989_2	335543.Sfum_3316	2.14e-57	190.0	COG1566@1|root,COG1566@2|Bacteria,1MU7I@1224|Proteobacteria,42NIC@68525|delta/epsilon subdivisions,2WKV5@28221|Deltaproteobacteria,2MQDK@213462|Syntrophobacterales	28221|Deltaproteobacteria	V	HlyD membrane-fusion protein of T1SS	-	-	-	ko:K03543	-	M00701	-	-	ko00000,ko00002,ko02000	8.A.1.1	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
k59_120392_1	1173022.Cri9333_3469	3.16e-152	446.0	COG1506@1|root,COG1506@2|Bacteria,1G200@1117|Cyanobacteria,1H8T3@1150|Oscillatoriales	1117|Cyanobacteria	E	PFAM Prolyl oligopeptidase family	dap2	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
k59_204187_1	1042326.AZNV01000013_gene3416	3.99e-46	164.0	COG0596@1|root,COG0596@2|Bacteria,1MWVN@1224|Proteobacteria,2TQVB@28211|Alphaproteobacteria,4B7GV@82115|Rhizobiaceae	28211|Alphaproteobacteria	Q	epoxide hydrolase	-	-	3.3.2.9	ko:K01253,ko:K21159	ko00980,ko01059,ko04976,ko05204,map00980,map01059,map04976,map05204	-	R07013,R07014,R07027,R07071,R07072,R07082,R09410,R09417,R09443	RC01447,RC01728,RC01764,RC02528	ko00000,ko00001,ko01000,ko01002	-	-	-	EHN
k59_226561_1	1209989.TepiRe1_1693	1.52e-15	72.4	COG2119@1|root,COG2119@2|Bacteria,1VI2Y@1239|Firmicutes,24RBN@186801|Clostridia,42H8V@68295|Thermoanaerobacterales	186801|Clostridia	S	Uncharacterized protein family UPF0016	-	-	-	-	-	-	-	-	-	-	-	-	UPF0016
k59_180845_1	880072.Desac_2446	4.6e-87	272.0	COG2812@1|root,COG2812@2|Bacteria,1MVCK@1224|Proteobacteria,42M09@68525|delta/epsilon subdivisions,2WJ1G@28221|Deltaproteobacteria,2MQ7N@213462|Syntrophobacterales	28221|Deltaproteobacteria	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
k59_5926_1	439235.Dalk_5173	8.29e-51	180.0	COG2204@1|root,COG4191@1|root,COG2204@2|Bacteria,COG4191@2|Bacteria,1R891@1224|Proteobacteria,42P2C@68525|delta/epsilon subdivisions,2WJZT@28221|Deltaproteobacteria,2MIG9@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
k59_136223_1	335543.Sfum_0824	1.37e-75	252.0	COG0493@1|root,COG1148@1|root,COG0493@2|Bacteria,COG1148@2|Bacteria,1MU2H@1224|Proteobacteria,42M6X@68525|delta/epsilon subdivisions,2X6YD@28221|Deltaproteobacteria,2MQTQ@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.17.1.10,1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388,ko:K15022	ko00680,ko00720,ko01100,ko01120,ko01200,map00680,map00720,map01100,map01120,map01200	M00356,M00357,M00377,M00563,M00567	R00134,R04540,R11928,R11931,R11943,R11944	RC00011,RC02796	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_20,Pyr_redox_2
k59_150443_1	1121405.dsmv_2115	4.46e-26	97.4	COG1758@1|root,COG1758@2|Bacteria,1N6TX@1224|Proteobacteria,42V07@68525|delta/epsilon subdivisions,2WRQ6@28221|Deltaproteobacteria,2MKV2@213118|Desulfobacterales	28221|Deltaproteobacteria	K	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits	rpoZ	-	2.7.7.6	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb6
k59_37432_1	667014.Thein_2048	1.8e-41	150.0	COG3264@1|root,COG3264@2|Bacteria,2GHQX@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	M	Mechanosensitive ion channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel
k59_90310_1	586416.GZ22_11235	1.27e-19	92.4	COG0037@1|root,COG0037@2|Bacteria,1TPXP@1239|Firmicutes,4H9ZM@91061|Bacilli	91061|Bacilli	D	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	2.4.2.8,6.3.4.19	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	-	R01132,R01229,R02142,R09597	RC00063,RC00122,RC02633,RC02634	ko00000,ko00001,ko01000,ko03016	-	-	-	ATP_bind_3,TilS,TilS_C
k59_120409_1	1121405.dsmv_1087	6.78e-74	254.0	COG1198@1|root,COG1198@2|Bacteria,1MUUZ@1224|Proteobacteria,42MNH@68525|delta/epsilon subdivisions,2WJ4G@28221|Deltaproteobacteria,2MINK@213118|Desulfobacterales	28221|Deltaproteobacteria	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,ResIII
k59_105737_1	153948.NAL212_0013	2.27e-109	320.0	COG3676@1|root,COG3676@2|Bacteria,1QTF7@1224|Proteobacteria,2VSUV@28216|Betaproteobacteria	28216|Betaproteobacteria	L	ISXO2-like transposase domain	-	-	-	ko:K07488	-	-	-	-	ko00000	-	-	-	DDE_Tnp_IS1595
k59_90314_2	177437.HRM2_11450	6.8e-43	145.0	COG0461@1|root,COG0461@2|Bacteria,1PI8N@1224|Proteobacteria,42QSR@68525|delta/epsilon subdivisions,2WMT5@28221|Deltaproteobacteria,2MJH0@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	pyrE	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran
k59_37438_1	56780.SYN_00295	6.58e-40	149.0	COG0366@1|root,COG3408@1|root,COG0366@2|Bacteria,COG3408@2|Bacteria,1MWBZ@1224|Proteobacteria,43AE9@68525|delta/epsilon subdivisions,2X5U3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	Alpha amylase catalytic	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase,GDE_C,GDE_N
k59_52028_1	1499967.BAYZ01000094_gene4042	4.54e-94	288.0	2DBFF@1|root,2Z8YA@2|Bacteria	2|Bacteria	L	PFAM transposase, IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_4,HTH_Tnp_4
k59_113227_1	933262.AXAM01000015_gene116	1.38e-65	216.0	COG0728@1|root,COG0728@2|Bacteria,1MUH0@1224|Proteobacteria,42M28@68525|delta/epsilon subdivisions,2WJPF@28221|Deltaproteobacteria,2MIBD@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane	murJ	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
k59_105740_1	370438.PTH_2420	9.81e-83	262.0	COG4865@1|root,COG4865@2|Bacteria,1TS6B@1239|Firmicutes,24AYE@186801|Clostridia,2610W@186807|Peptococcaceae	186801|Clostridia	E	Catalyzes the carbon skeleton rearrangement of L- glutamate to L-threo-3-methylaspartate ((2S,3S)-3- methylaspartate)	glmE	-	5.4.99.1	ko:K19268	ko00630,ko00660,ko01100,ko01200,map00630,map00660,map01100,map01200	M00740	R00262	RC01221	ko00000,ko00001,ko00002,ko01000	-	-	-	Met_asp_mut_E
k59_212022_1	313606.M23134_03049	3.05e-47	162.0	COG0332@1|root,COG0332@2|Bacteria,4NFIN@976|Bacteroidetes,47JAR@768503|Cytophagia	976|Bacteroidetes	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
k59_212022_2	29581.BW37_01645	9.27e-21	90.1	COG2267@1|root,COG2267@2|Bacteria,1NK3M@1224|Proteobacteria,2VKPD@28216|Betaproteobacteria,474PY@75682|Oxalobacteraceae	28216|Betaproteobacteria	I	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
k59_120433_2	331678.Cphamn1_0650	1.83e-07	53.5	COG3794@1|root,COG3794@2|Bacteria	2|Bacteria	C	PFAM blue (type 1) copper domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
k59_242228_1	1196323.ALKF01000101_gene9	1.96e-12	71.6	COG0488@1|root,COG0488@2|Bacteria,1TNYS@1239|Firmicutes,4HBFK@91061|Bacilli,26QVH@186822|Paenibacillaceae	91061|Bacilli	S	Glycosyl transferase family 1	yjcA	-	-	ko:K19350	ko02010,map02010	-	-	-	ko00000,ko00001,ko01504,ko02000	3.A.1.121	-	-	ABC_tran,ABC_tran_Xtn
k59_22373_1	1004149.AFOE01000006_gene2000	2.34e-43	149.0	COG2930@1|root,COG2930@2|Bacteria,4NP71@976|Bacteroidetes,1I20I@117743|Flavobacteriia	976|Bacteroidetes	S	Pfam Family of	-	-	-	-	-	-	-	-	-	-	-	-	Ysc84
k59_6556_1	96561.Dole_2313	3.47e-91	282.0	COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,42MEA@68525|delta/epsilon subdivisions,2WIW6@28221|Deltaproteobacteria,2MI74@213118|Desulfobacterales	28221|Deltaproteobacteria	KT	Sigma-54 interaction domain	-	-	2.1.1.80	ko:K00575	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	HTH_8,PAS_4,PAS_9,Sigma54_activat
k59_227237_1	933262.AXAM01000023_gene663	2.81e-68	226.0	COG0079@1|root,COG0283@1|root,COG0079@2|Bacteria,COG0283@2|Bacteria,1MW7I@1224|Proteobacteria,42NCH@68525|delta/epsilon subdivisions,2WJDR@28221|Deltaproteobacteria,2MIX3@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily	hisC	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
k59_242231_1	1346330.M472_11805	1.04e-18	81.3	COG1308@1|root,COG1308@2|Bacteria	2|Bacteria	K	protein transport	-	-	-	-	-	-	-	-	-	-	-	-	DUF4342
k59_242231_2	45351.EDO38962	2.75e-07	49.7	COG0532@1|root,KOG1144@2759|Eukaryota,38DE9@33154|Opisthokonta,3BBMB@33208|Metazoa	33208|Metazoa	J	eukaryotic translation initiation factor	EIF5B	GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006417,GO:0006446,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0017151,GO:0019222,GO:0019538,GO:0019899,GO:0031323,GO:0031326,GO:0032268,GO:0034248,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051246,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2000112	-	ko:K03243,ko:K12162	ko03013,map03013	-	-	-	ko00000,ko00001,ko03012,ko04121	-	-	-	GTP_EFTU,GTP_EFTU_D2,IF-2
k59_219562_1	573370.DMR_17610	7.17e-69	209.0	COG2033@1|root,COG2033@2|Bacteria,1RHE0@1224|Proteobacteria,42SB9@68525|delta/epsilon subdivisions,2WP2D@28221|Deltaproteobacteria,2MBEZ@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	PFAM Desulfoferrodoxin ferrous iron-binding region	dfx	-	1.15.1.2	ko:K05919	-	-	-	-	ko00000,ko01000	-	-	-	Desulfoferrod_N,Desulfoferrodox
k59_174350_1	439235.Dalk_4073	8.89e-32	128.0	COG2208@1|root,COG2770@1|root,COG2208@2|Bacteria,COG2770@2|Bacteria,1R7B6@1224|Proteobacteria,42QKS@68525|delta/epsilon subdivisions,2WIW2@28221|Deltaproteobacteria,2MII8@213118|Desulfobacterales	28221|Deltaproteobacteria	KT	Sigma factor PP2C-like phosphatases	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,SpoIIE
k59_242241_1	933262.AXAM01000048_gene2583	1.86e-108	318.0	COG0052@1|root,COG0052@2|Bacteria,1MU33@1224|Proteobacteria,42M3Y@68525|delta/epsilon subdivisions,2WJH5@28221|Deltaproteobacteria,2MJCG@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Belongs to the universal ribosomal protein uS2 family	rpsB	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
k59_227245_1	113395.AXAI01000001_gene3185	2.22e-42	163.0	COG1289@1|root,COG1289@2|Bacteria,1Q5JG@1224|Proteobacteria,2VBX6@28211|Alphaproteobacteria,3K2KA@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Aromatic acid exporter family member 1	-	-	-	-	-	-	-	-	-	-	-	-	FUSC
k59_52795_1	335543.Sfum_3131	7.67e-23	92.8	COG4656@1|root,COG4656@2|Bacteria,1MWAX@1224|Proteobacteria,42NJM@68525|delta/epsilon subdivisions,2WJJB@28221|Deltaproteobacteria,2MRCN@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	Methylene-tetrahydrofolate reductase C terminal	-	-	-	-	-	-	-	-	-	-	-	-	MTHFR_C
k59_52795_2	429009.Adeg_0343	2e-47	156.0	COG1908@1|root,COG1908@2|Bacteria,1V638@1239|Firmicutes,24J0E@186801|Clostridia,42IDY@68295|Thermoanaerobacterales	186801|Clostridia	C	Methyl-viologen-reducing hydrogenase, delta subunit	-	-	-	-	-	-	-	-	-	-	-	-	FlpD
k59_98525_1	1232437.KL662061_gene4190	5.89e-13	66.6	COG4656@1|root,COG4656@2|Bacteria,1MWAX@1224|Proteobacteria,42NJM@68525|delta/epsilon subdivisions,2WJJB@28221|Deltaproteobacteria,2MMJW@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Methylene-tetrahydrofolate reductase C terminal	-	-	-	-	-	-	-	-	-	-	-	-	MTHFR_C
k59_242244_1	1121405.dsmv_3071	3.9e-75	233.0	COG0834@1|root,COG0834@2|Bacteria,1MWDK@1224|Proteobacteria,42NVT@68525|delta/epsilon subdivisions,2WIRY@28221|Deltaproteobacteria,2MI8X@213118|Desulfobacterales	28221|Deltaproteobacteria	ET	SMART ABC-type transporter, periplasmic subunit family 3, ionotropic glutamate receptor	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
k59_133146_1	1235457.C404_26095	3.55e-81	259.0	COG0465@1|root,COG0465@2|Bacteria,1MU6J@1224|Proteobacteria,2VHEM@28216|Betaproteobacteria,1K0XH@119060|Burkholderiaceae	28216|Betaproteobacteria	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	-	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
k59_80025_1	879212.DespoDRAFT_02486	8.59e-50	160.0	COG0100@1|root,COG0100@2|Bacteria,1RD0A@1224|Proteobacteria,42R43@68525|delta/epsilon subdivisions,2WPH1@28221|Deltaproteobacteria,2MJYB@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome	rpsK	GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
k59_57372_1	795359.TOPB45_0431	3.94e-120	354.0	COG0536@1|root,COG0536@2|Bacteria,2GHPW@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	-	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	GTP1_OBG,MMR_HSR1
k59_57372_2	1121405.dsmv_3222	7.73e-39	130.0	COG0211@1|root,COG0211@2|Bacteria,1MZGH@1224|Proteobacteria,42THK@68525|delta/epsilon subdivisions,2WQ2U@28221|Deltaproteobacteria,2MKMM@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Belongs to the bacterial ribosomal protein bL27 family	rpmA	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02899	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27
k59_102748_1	177439.DP0642	1.83e-43	153.0	COG0079@1|root,COG0079@2|Bacteria,1MW7I@1224|Proteobacteria,42NCH@68525|delta/epsilon subdivisions,2WJDR@28221|Deltaproteobacteria,2MIX3@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily	hisC	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
k59_117324_1	1265505.ATUG01000001_gene3467	4.2e-43	160.0	COG2199@1|root,COG2202@1|root,COG2202@2|Bacteria,COG3706@2|Bacteria,1MZV7@1224|Proteobacteria,42S7S@68525|delta/epsilon subdivisions,2WNFR@28221|Deltaproteobacteria,2MJU7@213118|Desulfobacterales	28221|Deltaproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GGDEF,PAS,PAS_3,PAS_4
k59_80028_1	525904.Tter_2546	6.4e-23	100.0	COG0589@1|root,COG0589@2|Bacteria,2NRGN@2323|unclassified Bacteria	2|Bacteria	T	PFAM UspA domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
k59_133152_1	1121405.dsmv_3101	1.1e-80	253.0	COG0592@1|root,COG0592@2|Bacteria,1MVD9@1224|Proteobacteria,42NQW@68525|delta/epsilon subdivisions,2WJZM@28221|Deltaproteobacteria,2MHS9@213118|Desulfobacterales	28221|Deltaproteobacteria	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	dnaN	-	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
k59_133152_2	933262.AXAM01000032_gene686	9.98e-60	191.0	COG2974@1|root,COG2974@2|Bacteria,1RCUH@1224|Proteobacteria,42QVW@68525|delta/epsilon subdivisions,2WN5B@28221|Deltaproteobacteria,2MJPM@213118|Desulfobacterales	28221|Deltaproteobacteria	L	May be involved in recombination	-	-	-	-	-	-	-	-	-	-	-	-	RdgC
k59_49343_1	335543.Sfum_3317	5.77e-90	279.0	COG0477@1|root,COG2814@2|Bacteria,1MU1I@1224|Proteobacteria,42KZU@68525|delta/epsilon subdivisions,2WJ6T@28221|Deltaproteobacteria,2MSKS@213462|Syntrophobacterales	28221|Deltaproteobacteria	P	PFAM major facilitator superfamily MFS_1	-	-	-	ko:K03446	-	M00701	-	-	ko00000,ko00002,ko02000	2.A.1.3	-	-	MFS_1
k59_177999_1	1121405.dsmv_0179	5.1e-90	271.0	COG1573@1|root,COG1573@2|Bacteria,1PIX8@1224|Proteobacteria,42P41@68525|delta/epsilon subdivisions,2WM40@28221|Deltaproteobacteria,2MN8M@213118|Desulfobacterales	28221|Deltaproteobacteria	L	PFAM Uracil-DNA glycosylase superfamily	-	-	-	ko:K10800	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
k59_201248_1	667014.Thein_0253	2.87e-87	267.0	COG0473@1|root,COG0473@2|Bacteria,2GGUW@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	CE	Isocitrate/isopropylmalate dehydrogenase	-	-	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
k59_72414_1	1121904.ARBP01000003_gene6591	2.87e-50	179.0	COG0531@1|root,COG0531@2|Bacteria,4NDU2@976|Bacteroidetes,47JF7@768503|Cytophagia	976|Bacteroidetes	E	PFAM amino acid permease-associated region	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease,AA_permease_2,AA_permease_C,PTS_EIIA_2,TrkA_C,Usp
k59_95074_1	1499967.BAYZ01000048_gene2700	9.34e-103	310.0	COG2211@1|root,COG2211@2|Bacteria	2|Bacteria	G	Major facilitator Superfamily	-	-	-	ko:K03292	-	-	-	-	ko00000	2.A.2	-	-	MFS_2,MFS_3
k59_34541_1	858215.Thexy_1688	2.32e-109	324.0	COG1606@1|root,COG1606@2|Bacteria,1TPB2@1239|Firmicutes,2485J@186801|Clostridia,42FCT@68295|Thermoanaerobacterales	186801|Clostridia	S	PFAM PP-loop domain protein	-	-	-	ko:K06864	-	-	-	-	ko00000	-	-	-	ATP_bind_3,NAD_synthase
k59_133160_1	247490.KSU1_B0348	3.17e-67	211.0	COG0501@1|root,COG0501@2|Bacteria,2J512@203682|Planctomycetes	203682|Planctomycetes	O	Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
k59_125608_1	335543.Sfum_0822	1.26e-111	331.0	COG1035@1|root,COG1152@1|root,COG1035@2|Bacteria,COG1152@2|Bacteria,1R4GN@1224|Proteobacteria,42P9J@68525|delta/epsilon subdivisions,2WJ9S@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	1.17.1.9	ko:K00125	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Fer4,Fer4_17,FrhB_FdhB_C
k59_238749_1	573370.DMR_18670	8.19e-76	247.0	COG0507@1|root,COG0507@2|Bacteria,1MW43@1224|Proteobacteria,42M8J@68525|delta/epsilon subdivisions,2WJD6@28221|Deltaproteobacteria,2M9DU@213115|Desulfovibrionales	28221|Deltaproteobacteria	L	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity	recD2	-	3.1.11.5	ko:K03581	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AAA_30,HHH_4,HHH_5,UvrD_C_2
k59_140742_1	146922.JOFU01000012_gene1844	4.79e-05	49.3	COG2267@1|root,COG2267@2|Bacteria,2I2GI@201174|Actinobacteria	201174|Actinobacteria	I	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
k59_140742_2	644282.Deba_0653	1.36e-58	200.0	COG1906@1|root,COG1906@2|Bacteria,1RAQQ@1224|Proteobacteria,42QZ0@68525|delta/epsilon subdivisions,2WMXK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Protein of unknown function (DUF401)	-	-	-	ko:K09133	-	-	-	-	ko00000	-	-	-	DUF401
k59_34548_1	1232437.KL662031_gene2534	2.99e-37	132.0	COG2197@1|root,COG2197@2|Bacteria,1MWGM@1224|Proteobacteria,42Q40@68525|delta/epsilon subdivisions,2WKYI@28221|Deltaproteobacteria,2MJHB@213118|Desulfobacterales	28221|Deltaproteobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	ko:K02479	-	-	-	-	ko00000,ko02022	-	-	-	GerE,Response_reg
k59_34548_2	1384057.CD33_07405	1.1e-10	64.7	COG4585@1|root,COG4585@2|Bacteria,1UYVE@1239|Firmicutes,4HGNS@91061|Bacilli,3IZK8@400634|Lysinibacillus	91061|Bacilli	T	Histidine kinase	ydfH	-	2.7.13.3	ko:K11623	ko02020,map02020	M00484	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA_3
k59_3394_1	1415780.JPOG01000001_gene2500	2.93e-33	127.0	COG0789@1|root,COG5012@1|root,COG0789@2|Bacteria,COG5012@2|Bacteria,1R9SN@1224|Proteobacteria,1SFN0@1236|Gammaproteobacteria,1X7VP@135614|Xanthomonadales	135614|Xanthomonadales	K	B12 binding domain	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,B12-binding_2,MerR_1
k59_186465_1	563192.HMPREF0179_00536	1.23e-58	199.0	COG1053@1|root,COG1053@2|Bacteria,1NZBR@1224|Proteobacteria,42QFY@68525|delta/epsilon subdivisions,2WK27@28221|Deltaproteobacteria,2MGKN@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	Fumarate reductase flavoprotein C-term	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_2,Succ_DH_flav_C
k59_64476_1	1123290.AUDQ01000020_gene697	1.34e-16	87.0	COG4974@1|root,COG4974@2|Bacteria,1TQXV@1239|Firmicutes,4HD04@91061|Bacilli,26ERV@186818|Planococcaceae	91061|Bacilli	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_1,Phage_int_SAM_4,Phage_integrase
k59_80056_1	991905.SL003B_0831	3.98e-94	296.0	COG1022@1|root,COG1022@2|Bacteria,1MU4D@1224|Proteobacteria,2TSSI@28211|Alphaproteobacteria,4BRTC@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	I	AMP-binding enzyme	fadD3	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
k59_170954_2	543632.JOJL01000002_gene8102	5.12e-21	100.0	COG1032@1|root,COG1032@2|Bacteria,2HWUC@201174|Actinobacteria,4DKD5@85008|Micromonosporales	201174|Actinobacteria	C	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
k59_18958_2	96561.Dole_0341	3.48e-55	186.0	COG0504@1|root,COG0504@2|Bacteria,1MUIT@1224|Proteobacteria,42MEU@68525|delta/epsilon subdivisions,2WJ0F@28221|Deltaproteobacteria,2MHTP@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1276	CTP_synth_N,GATase
k59_125628_1	1167006.UWK_00560	4.05e-51	181.0	COG3005@1|root,COG3005@2|Bacteria,1NFFE@1224|Proteobacteria,430BS@68525|delta/epsilon subdivisions,2WVRX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Doubled CXXCH motif (Paired_CXXCH_1)	-	-	-	-	-	-	-	-	-	-	-	-	Paired_CXXCH_1
k59_193200_1	1203554.HMPREF1476_00826	3.47e-48	170.0	COG1053@1|root,COG1053@2|Bacteria,1MURY@1224|Proteobacteria,2W147@28216|Betaproteobacteria,4PQ4X@995019|Sutterellaceae	28216|Betaproteobacteria	C	NAD(P)-binding Rossmann-like domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_2
k59_87281_2	1125863.JAFN01000001_gene1654	9.32e-38	144.0	2A6A4@1|root,30V2R@2|Bacteria,1RENE@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4382
k59_216679_2	96561.Dole_1461	9.08e-69	227.0	COG0369@1|root,COG1151@2|Bacteria,1NYH2@1224|Proteobacteria,42NE1@68525|delta/epsilon subdivisions,2WIVX@28221|Deltaproteobacteria,2MINQ@213118|Desulfobacterales	28221|Deltaproteobacteria	C	TIGRFAM carbon-monoxide dehydrogenase, catalytic subunit	-	-	1.2.7.4	ko:K00198	ko00633,ko00680,ko00720,ko01120,ko01200,map00633,map00680,map00720,map01120,map01200	M00377	R07157,R08034	RC00250,RC02800	ko00000,ko00001,ko00002,ko01000	-	-	-	Prismane
k59_87760_1	1265505.ATUG01000001_gene3093	8.63e-163	474.0	28I8B@1|root,2Z8B5@2|Bacteria,1MUNM@1224|Proteobacteria,42NZH@68525|delta/epsilon subdivisions,2WKHB@28221|Deltaproteobacteria,2MISZ@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM Cytochrome c, bacterial	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554,Cytochrome_C7,Cytochrome_cB
k59_239104_1	497321.C664_15453	9.28e-71	244.0	COG0178@1|root,COG0178@2|Bacteria,1MW0W@1224|Proteobacteria,2VI87@28216|Betaproteobacteria,2KVBJ@206389|Rhodocyclales	206389|Rhodocyclales	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	-	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
k59_12530_1	933262.AXAM01000060_gene2892	8.85e-80	251.0	COG4191@1|root,COG4191@2|Bacteria,1MY5P@1224|Proteobacteria,42MTA@68525|delta/epsilon subdivisions,2WJ9Q@28221|Deltaproteobacteria,2MIRX@213118|Desulfobacterales	28221|Deltaproteobacteria	T	PFAM ATP-binding region ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	4HB_MCP_1,CHASE3,HAMP,HATPase_c,HisKA
k59_19447_1	279006.D9I6A7_9CAUD	3.32e-07	57.0	4QBAK@10239|Viruses,4QY34@35237|dsDNA viruses  no RNA stage,4QQBQ@28883|Caudovirales,4QIQI@10662|Myoviridae	10662|Myoviridae	S	Bacteriophage T4-like capsid assembly protein (Gp20)	-	GO:0005575,GO:0019012	-	-	-	-	-	-	-	-	-	-	-
k59_41998_1	429009.Adeg_0257	6.84e-31	129.0	COG0438@1|root,COG1216@1|root,COG2227@1|root,COG0438@2|Bacteria,COG1216@2|Bacteria,COG2227@2|Bacteria,1UYRR@1239|Firmicutes,249T1@186801|Clostridia,42HAT@68295|Thermoanaerobacterales	186801|Clostridia	M	PFAM Glycosyl transferase family 2	-	-	-	ko:K07011,ko:K20444	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.1.3	GT2,GT4	-	Glyco_tranf_2_3,Glyco_trans_2_3,Glycos_transf_2,Methyltransf_23
k59_156426_1	883.DvMF_0625	1.07e-28	112.0	COG2427@1|root,COG2427@2|Bacteria,1P6AT@1224|Proteobacteria,43355@68525|delta/epsilon subdivisions,2WXWE@28221|Deltaproteobacteria,2MBQA@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF1641)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1641
k59_239109_2	1319815.HMPREF0202_02525	2.46e-20	91.7	COG2985@1|root,COG2985@2|Bacteria	2|Bacteria	S	potassium ion transport	aspT	-	-	ko:K07085	-	-	-	-	ko00000	2.A.81	-	-	Asp-Al_Ex,TrkA_C
k59_72935_1	640511.BC1002_4502	4.52e-87	263.0	COG3910@1|root,COG3910@2|Bacteria,1MZSY@1224|Proteobacteria,2VKJV@28216|Betaproteobacteria,1K0Z6@119060|Burkholderiaceae	28216|Betaproteobacteria	S	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_21,AAA_23
k59_239111_1	96561.Dole_3193	3.43e-99	305.0	COG2199@1|root,COG3850@1|root,COG2199@2|Bacteria,COG3850@2|Bacteria,1NT1K@1224|Proteobacteria,42R1P@68525|delta/epsilon subdivisions,2WN0S@28221|Deltaproteobacteria,2MMVQ@213118|Desulfobacterales	28221|Deltaproteobacteria	T	PFAM GGDEF domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,HAMP
k59_224148_1	755732.Fluta_3961	4.65e-81	256.0	COG3666@1|root,COG3666@2|Bacteria,4NEDD@976|Bacteroidetes,1HYXT@117743|Flavobacteriia,2PC3Q@246874|Cryomorphaceae	976|Bacteroidetes	L	COGs COG3666 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_6,DUF772
k59_95656_1	870187.Thini_0408	8.62e-08	59.3	COG3209@1|root,COG3325@1|root,COG4222@1|root,COG3209@2|Bacteria,COG3325@2|Bacteria,COG4222@2|Bacteria	2|Bacteria	S	Esterase-like activity of phytase	-	-	-	ko:K03929	-	-	-	-	ko00000,ko01000	-	CE10	-	DUF4849,Phytase-like
k59_186947_1	243159.AFE_1843	8.02e-85	270.0	COG0021@1|root,COG0021@2|Bacteria,1MUEY@1224|Proteobacteria,1SJQ1@1236|Gammaproteobacteria,2NDRU@225057|Acidithiobacillales	225057|Acidithiobacillales	G	Transketolase, thiamine diphosphate binding domain	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
k59_64867_1	1125863.JAFN01000001_gene3180	5.77e-19	86.3	COG0071@1|root,COG0071@2|Bacteria,1N7C7@1224|Proteobacteria,42U0T@68525|delta/epsilon subdivisions,2WRBN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
k59_49827_1	335543.Sfum_3868	1.47e-28	108.0	COG0703@1|root,COG0703@2|Bacteria,1NEB0@1224|Proteobacteria	1224|Proteobacteria	E	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_232367_1	316067.Geob_0251	1.55e-40	146.0	COG1143@1|root,COG2025@1|root,COG1143@2|Bacteria,COG2025@2|Bacteria,1MUFI@1224|Proteobacteria,42M3T@68525|delta/epsilon subdivisions,2WIV8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	electron transfer flavoprotein, alpha subunit	etfA-2	-	-	ko:K03522	-	-	-	-	ko00000,ko04147	-	-	iAF987.Gmet_2066	ETF,ETF_alpha,Fer4,Fer4_4
k59_193640_1	485913.Krac_2547	1.11e-120	361.0	COG0492@1|root,COG0492@2|Bacteria,2G5Z5@200795|Chloroflexi	2|Bacteria	C	FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Glutaredoxin,Pyr_redox_2
k59_26852_1	335543.Sfum_3071	5.23e-119	349.0	COG0682@1|root,COG0682@2|Bacteria,1MVE3@1224|Proteobacteria,42M2I@68525|delta/epsilon subdivisions,2WMSH@28221|Deltaproteobacteria,2MQBV@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
k59_57898_1	572478.Vdis_1836	6.24e-64	219.0	COG0417@1|root,arCOG15272@2157|Archaea,2XPPT@28889|Crenarchaeota	28889|Crenarchaeota	L	SMART DNA-directed DNA polymerase B	dpo1	-	2.7.7.7	ko:K02319	ko00230,ko00240,ko01100,ko03030,map00230,map00240,map01100,map03030	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032	-	-	-	DNA_pol_B,DNA_pol_B_exo1
k59_3830_2	56780.SYN_03783	1.29e-40	137.0	2FA5F@1|root,33ZQN@2|Bacteria,1NXGX@1224|Proteobacteria,430AQ@68525|delta/epsilon subdivisions,2WW50@28221|Deltaproteobacteria,2MS2H@213462|Syntrophobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_3830_3	449673.BACSTE_03607	1.34e-06	48.9	COG1704@1|root,COG1704@2|Bacteria,4NMD3@976|Bacteroidetes,2FNPV@200643|Bacteroidia,4AMZ9@815|Bacteroidaceae	976|Bacteroidetes	S	LemA family	lemA	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
k59_117849_1	269799.Gmet_1586	1.34e-37	145.0	COG0532@1|root,COG0532@2|Bacteria,1MV26@1224|Proteobacteria,42M5Q@68525|delta/epsilon subdivisions,2WIIX@28221|Deltaproteobacteria,43UH5@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,IF-2,IF2_N
k59_117850_1	1123354.AUDR01000002_gene1517	8.87e-32	116.0	COG0590@1|root,COG0590@2|Bacteria,1RGU0@1224|Proteobacteria,2VR60@28216|Betaproteobacteria,1KRP6@119069|Hydrogenophilales	119069|Hydrogenophilales	FJ	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)	tadA	-	3.5.4.33	ko:K11991	-	-	R10223	RC00477	ko00000,ko01000,ko03016	-	-	-	MafB19-deam
k59_87794_1	177437.HRM2_02570	1.47e-47	163.0	COG1418@1|root,COG1418@2|Bacteria,1RGCM@1224|Proteobacteria,42RC5@68525|delta/epsilon subdivisions,2WNBA@28221|Deltaproteobacteria,2MJS4@213118|Desulfobacterales	28221|Deltaproteobacteria	S	mRNA catabolic process	-	-	-	-	-	-	-	-	-	-	-	-	HD
k59_87794_2	926550.CLDAP_09070	7e-40	144.0	COG3191@1|root,COG3191@2|Bacteria,2G6BG@200795|Chloroflexi	200795|Chloroflexi	EQ	PFAM peptidase S58, DmpA	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S58
k59_35112_1	1089552.KI911559_gene2410	4.53e-73	236.0	COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,2TQW5@28211|Alphaproteobacteria,2JQEC@204441|Rhodospirillales	204441|Rhodospirillales	G	COG1593 TRAP-type C4-dicarboxylate transport system, large permease component	-	-	-	-	-	-	-	-	-	-	-	-	DctM
k59_87799_1	696281.Desru_2733	1e-66	207.0	COG0778@1|root,COG0778@2|Bacteria,1V3YJ@1239|Firmicutes,24MER@186801|Clostridia,266UI@186807|Peptococcaceae	186801|Clostridia	C	Putative TM nitroreductase	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
k59_205213_1	335543.Sfum_3226	5.35e-46	161.0	COG0589@1|root,COG0589@2|Bacteria,1REA3@1224|Proteobacteria,42RXY@68525|delta/epsilon subdivisions,2WNM6@28221|Deltaproteobacteria,2MSDJ@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	PFAM UspA domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
k59_30768_1	1242864.D187_007269	2.74e-38	142.0	COG0265@1|root,COG0265@2|Bacteria,1NXB0@1224|Proteobacteria	1224|Proteobacteria	O	Trypsin-like peptidase domain	-	-	-	-	-	-	-	-	-	-	-	-	Trypsin_2
k59_30768_2	138119.DSY1906	0.00014	43.1	COG5496@1|root,COG5496@2|Bacteria,1VAZJ@1239|Firmicutes,24MWR@186801|Clostridia,262M7@186807|Peptococcaceae	186801|Clostridia	S	PFAM thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
k59_30771_1	1304872.JAGC01000003_gene2354	2.68e-68	222.0	COG1520@1|root,COG1520@2|Bacteria,1NYGT@1224|Proteobacteria,42TY0@68525|delta/epsilon subdivisions,2WQ74@28221|Deltaproteobacteria,2M9SS@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Arylsulfotransferase (ASST)	-	-	-	-	-	-	-	-	-	-	-	-	Arylsulfotran_2,Arylsulfotrans
k59_159716_1	933262.AXAM01000019_gene1127	2.89e-37	125.0	COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,42V0K@68525|delta/epsilon subdivisions,2WR92@28221|Deltaproteobacteria,2MKYU@213118|Desulfobacterales	28221|Deltaproteobacteria	K	PFAM Cold-shock	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
k59_8064_1	398767.Glov_1920	2.78e-59	199.0	COG0793@1|root,COG0793@2|Bacteria,1MU39@1224|Proteobacteria,42MHD@68525|delta/epsilon subdivisions,2WJKC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Belongs to the peptidase S41A family	ctpA	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_S41
k59_159720_1	1220534.B655_0034	5.02e-95	281.0	COG1853@1|root,arCOG02016@2157|Archaea,2Y8H6@28890|Euryarchaeota,23PZP@183925|Methanobacteria	183925|Methanobacteria	S	Flavin reductase like domain	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
k59_53518_1	767817.Desgi_2707	3.76e-32	129.0	COG0446@1|root,COG1902@1|root,COG0446@2|Bacteria,COG1902@2|Bacteria,1TPM6@1239|Firmicutes,247V1@186801|Clostridia,260YA@186807|Peptococcaceae	186801|Clostridia	C	NADH flavin oxidoreductase NADH oxidase	-	-	1.3.1.34	ko:K00219	-	-	-	-	ko00000,ko01000	-	-	-	ADC,Oxidored_FMN,Pyr_redox_2
k59_91377_1	1265505.ATUG01000002_gene1613	2.35e-44	163.0	COG2204@1|root,COG3829@1|root,COG2204@2|Bacteria,COG3829@2|Bacteria,1MU0N@1224|Proteobacteria,43CWU@68525|delta/epsilon subdivisions	1224|Proteobacteria	T	Bacterial regulatory protein, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
k59_189935_1	1121918.ARWE01000001_gene3254	3.63e-68	217.0	COG3547@1|root,COG3547@2|Bacteria,1MUER@1224|Proteobacteria,42WT2@68525|delta/epsilon subdivisions,2WR9X@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	transposase IS116 IS110 IS902 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_30780_1	933262.AXAM01000013_gene1300	4.28e-09	63.9	COG4796@1|root,COG4796@2|Bacteria,1QTT6@1224|Proteobacteria,42MKN@68525|delta/epsilon subdivisions,2WJV6@28221|Deltaproteobacteria,2MHUC@213118|Desulfobacterales	28221|Deltaproteobacteria	U	type II and III secretion system protein	pilQ	-	-	ko:K02666	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	AMIN,STN,Secretin,Secretin_N
k59_15586_1	945713.IALB_0566	1.1e-27	103.0	COG2963@1|root,COG2963@2|Bacteria	2|Bacteria	L	transposase activity	-	-	-	ko:K07483	-	-	-	-	ko00000	-	-	-	HTH_28,HTH_Tnp_1
k59_235495_1	1265505.ATUG01000002_gene1830	3.05e-82	251.0	COG1024@1|root,COG1024@2|Bacteria,1R7WW@1224|Proteobacteria,42NZQ@68525|delta/epsilon subdivisions,2WMCW@28221|Deltaproteobacteria,2MJ0F@213118|Desulfobacterales	28221|Deltaproteobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	4.2.1.100	ko:K07537	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00541	R05597	RC03168	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
k59_91381_1	1121403.AUCV01000056_gene3022	1.18e-71	224.0	COG0330@1|root,COG0330@2|Bacteria,1MV7R@1224|Proteobacteria,42N2V@68525|delta/epsilon subdivisions,2WIPS@28221|Deltaproteobacteria,2MIPC@213118|Desulfobacterales	28221|Deltaproteobacteria	O	HflC and HflK could regulate a protease	hflC	-	-	ko:K04087	-	M00742	-	-	ko00000,ko00002,ko01000	-	-	-	Band_7
k59_446_2	237368.SCABRO_01861	8.38e-29	111.0	COG3218@1|root,COG3218@2|Bacteria	2|Bacteria	Q	ABC-type transport auxiliary lipoprotein component	-	-	-	ko:K18480	-	M00669	-	-	ko00000,ko00002,ko02000	3.A.1.27.1	-	-	ABC_trans_aux
k59_152056_1	1110502.TMO_0669	1.44e-06	56.2	COG0025@1|root,COG0664@1|root,COG0025@2|Bacteria,COG0664@2|Bacteria,1MW5T@1224|Proteobacteria,2TSHB@28211|Alphaproteobacteria,2JQD0@204441|Rhodospirillales	204441|Rhodospirillales	PT	Sodium/hydrogen exchanger family	-	-	-	ko:K03316	-	-	-	-	ko00000	2.A.36	-	-	Na_H_Exchanger,cNMP_binding
k59_152056_2	643648.Slip_0220	1.26e-15	77.4	COG1122@1|root,COG1122@2|Bacteria,1TPH8@1239|Firmicutes,248A2@186801|Clostridia,42KB7@68298|Syntrophomonadaceae	186801|Clostridia	P	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates	ecfA	-	-	ko:K16786,ko:K16787	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ABC_tran
k59_30785_1	933262.AXAM01000069_gene2697	9.1e-60	188.0	COG0146@1|root,COG0146@2|Bacteria,1QU46@1224|Proteobacteria,43CGH@68525|delta/epsilon subdivisions,2WJ3J@28221|Deltaproteobacteria,2MPPC@213118|Desulfobacterales	28221|Deltaproteobacteria	EQ	Hydantoinase B/oxoprolinase	hyuB	-	3.5.2.14	ko:K01474	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydantoinase_B
k59_129354_1	370438.PTH_2418	2.18e-44	159.0	COG2079@1|root,COG2079@2|Bacteria,1TSD7@1239|Firmicutes,24BFZ@186801|Clostridia,260NH@186807|Peptococcaceae	186801|Clostridia	S	PFAM MmgE PrpD	-	-	-	-	-	-	-	-	-	-	-	-	MmgE_PrpD
k59_121758_1	335543.Sfum_0226	1.78e-42	145.0	COG0782@1|root,COG0782@2|Bacteria,1RCXW@1224|Proteobacteria,42SDX@68525|delta/epsilon subdivisions,2WP41@28221|Deltaproteobacteria,2MQIH@213462|Syntrophobacterales	28221|Deltaproteobacteria	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	-	-	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
k59_83809_1	94624.Bpet3616	2.12e-05	46.6	COG2318@1|root,COG2318@2|Bacteria,1RD3M@1224|Proteobacteria,2VSDB@28216|Betaproteobacteria,3T4UV@506|Alcaligenaceae	28216|Betaproteobacteria	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB
k59_83809_2	396588.Tgr7_2437	5.35e-25	94.7	COG2002@1|root,COG2002@2|Bacteria,1NBUR@1224|Proteobacteria,1SSDG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	SpoVT / AbrB like domain	-	-	-	-	-	-	-	-	-	-	-	-	MazE_antitoxin
k59_83809_3	166318.Syn8016DRAFT_1695	2.15e-12	62.0	COG1487@1|root,COG1487@2|Bacteria,1GPMC@1117|Cyanobacteria,1H3HK@1129|Synechococcus	1117|Cyanobacteria	S	ribonuclease activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_61715_2	1123060.JONP01000007_gene4983	0.000322	49.3	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2TQQ9@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,Response_reg
k59_137393_1	717231.Flexsi_2037	2.56e-19	87.0	COG0550@1|root,COG0551@1|root,COG0550@2|Bacteria,COG0551@2|Bacteria,2GESM@200930|Deferribacteres	200930|Deferribacteres	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,zf-C4_Topoisom
k59_137393_2	56780.SYN_02797	2.4e-64	211.0	COG0758@1|root,COG4277@1|root,COG0758@2|Bacteria,COG4277@2|Bacteria,1MVF6@1224|Proteobacteria,42N10@68525|delta/epsilon subdivisions,2WJI9@28221|Deltaproteobacteria,2MQD6@213462|Syntrophobacterales	28221|Deltaproteobacteria	L	TIGRFAM DNA protecting protein DprA	dprA	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A
k59_235979_1	290397.Adeh_2389	6.79e-68	216.0	COG0157@1|root,COG0157@2|Bacteria,1MW0C@1224|Proteobacteria,42MY7@68525|delta/epsilon subdivisions,2WJH7@28221|Deltaproteobacteria,2YUYQ@29|Myxococcales	28221|Deltaproteobacteria	H	Belongs to the NadC ModD family	nadC	-	2.4.2.19	ko:K00767	ko00760,ko01100,map00760,map01100	M00115	R03348	RC02877	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1988	QRPTase_C,QRPTase_N
k59_213101_1	596154.Alide2_3409	9.34e-86	265.0	COG3335@1|root,COG3415@1|root,COG3335@2|Bacteria,COG3415@2|Bacteria,1MW7X@1224|Proteobacteria,2VMDX@28216|Betaproteobacteria,4AAP5@80864|Comamonadaceae	28216|Betaproteobacteria	L	PFAM Integrase catalytic region	-	-	-	ko:K07494	-	-	-	-	ko00000	-	-	-	DDE_3,HTH_23,HTH_29,HTH_32
k59_76871_1	1120948.KB903217_gene1522	3.6e-10	62.8	COG0436@1|root,COG0436@2|Bacteria,2GJ7R@201174|Actinobacteria,4DY66@85010|Pseudonocardiales	201174|Actinobacteria	E	PFAM Aminotransferase class I and II	aspC	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
k59_76871_2	1121405.dsmv_0796	2.01e-63	202.0	COG0287@1|root,COG0287@2|Bacteria,1QA4K@1224|Proteobacteria,42V3B@68525|delta/epsilon subdivisions,2WRIN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Prephenate dehydrogenase	-	-	1.3.1.12	ko:K00210	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00025	R01728	RC00125	ko00000,ko00001,ko00002,ko01000	-	-	-	CM_2,PDH
k59_190355_1	1303518.CCALI_00159	4.7e-39	146.0	COG0466@1|root,COG0466@2|Bacteria	2|Bacteria	O	ATP-dependent peptidase activity	lon	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
k59_190355_2	1121438.JNJA01000001_gene2601	4.33e-13	68.9	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,2MG1U@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	Bacterial regulatory protein, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
k59_38850_2	933262.AXAM01000009_gene1481	9.19e-122	362.0	28MQN@1|root,2ZAZG@2|Bacteria,1MVVQ@1224|Proteobacteria,42MMM@68525|delta/epsilon subdivisions,2WKA1@28221|Deltaproteobacteria,2MHKP@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_152583_1	264732.Moth_1603	6.31e-104	310.0	COG5557@1|root,COG5557@2|Bacteria,1UYGM@1239|Firmicutes,24EQA@186801|Clostridia	186801|Clostridia	C	PFAM Polysulphide reductase, NrfD	-	-	-	ko:K00185	-	-	-	-	ko00000	5.A.3	-	-	NrfD
k59_8470_1	158190.SpiGrapes_2786	2.15e-155	442.0	COG1879@1|root,COG1879@2|Bacteria,2J72H@203691|Spirochaetes	203691|Spirochaetes	G	ABC-type sugar transport system periplasmic component	-	-	-	ko:K02058	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	Peripla_BP_4
k59_175294_1	1121405.dsmv_0316	1.92e-82	268.0	COG1048@1|root,COG1048@2|Bacteria,1MU9T@1224|Proteobacteria,42M33@68525|delta/epsilon subdivisions,2WJGS@28221|Deltaproteobacteria,2MIFE@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate	-	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
k59_235991_2	765420.OSCT_2000	3.65e-90	290.0	COG1026@1|root,COG1026@2|Bacteria,2G5Q4@200795|Chloroflexi,376S4@32061|Chloroflexia	32061|Chloroflexia	S	PFAM peptidase M16 domain protein	-	-	-	ko:K06972	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M16C_assoc,Peptidase_M16,Peptidase_M16_C
k59_198024_2	1123242.JH636434_gene3157	6.91e-22	102.0	COG0457@1|root,COG0457@2|Bacteria,2IZBG@203682|Planctomycetes	203682|Planctomycetes	M	SMART Tetratricopeptide domain protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_17,TPR_19,TPR_8
k59_23680_1	1232437.KL661969_gene4957	4.11e-69	224.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,2MIB8@213118|Desulfobacterales	28221|Deltaproteobacteria	T	response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
k59_235995_1	439235.Dalk_0392	1.65e-30	124.0	COG0457@1|root,COG0501@1|root,COG0457@2|Bacteria,COG0501@2|Bacteria,1R5A7@1224|Proteobacteria,42MP6@68525|delta/epsilon subdivisions,2WK92@28221|Deltaproteobacteria,2MIHI@213118|Desulfobacterales	28221|Deltaproteobacteria	O	PFAM peptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48,TPR_11,TPR_17
k59_122208_1	644282.Deba_0780	1.98e-20	92.4	COG1150@1|root,COG2181@1|root,COG1150@2|Bacteria,COG2181@2|Bacteria,1R44N@1224|Proteobacteria,42NTE@68525|delta/epsilon subdivisions,2WJN8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Nitrate reductase gamma subunit	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_17,Fer4_8,Nitrate_red_gam
k59_228249_1	642492.Clole_0332	3.03e-80	247.0	COG0739@1|root,COG0739@2|Bacteria,1UYKB@1239|Firmicutes,25B2K@186801|Clostridia	186801|Clostridia	M	Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
k59_23690_1	1177154.Y5S_01704	2.04e-45	167.0	COG1361@1|root,COG4932@1|root,COG1361@2|Bacteria,COG4932@2|Bacteria,1R5G4@1224|Proteobacteria,1SEWA@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Domain of unknown function DUF11	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,SdrD_B
k59_182828_1	1217652.F954_02868	8.28e-17	85.9	28JKJ@1|root,2Z9DD@2|Bacteria,1MUN2@1224|Proteobacteria,1RQIP@1236|Gammaproteobacteria,3NM6C@468|Moraxellaceae	1236|Gammaproteobacteria	S	Phage P22-like portal protein	-	-	-	-	-	-	-	-	-	-	-	-	P22_portal
k59_220920_1	509635.N824_29615	1.15e-12	75.1	COG2202@1|root,COG3290@1|root,COG4191@1|root,COG2202@2|Bacteria,COG3290@2|Bacteria,COG4191@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,GGDEF,HATPase_c,HATPase_c_2,HisKA,HisKA_3,PAS,PAS_3,PAS_4,PAS_9,STAS_2,SpoIIE
k59_228260_1	247490.KSU1_D0195	7.35e-75	238.0	COG1032@1|root,COG1032@2|Bacteria,2IXHH@203682|Planctomycetes	203682|Planctomycetes	C	Domain of unknown function (DUF4070)	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,DUF4070,Radical_SAM
k59_167635_1	883.DvMF_2629	3.92e-52	167.0	COG0662@1|root,COG0662@2|Bacteria,1N1XN@1224|Proteobacteria,42TS2@68525|delta/epsilon subdivisions,2WPZ5@28221|Deltaproteobacteria,2MCQX@213115|Desulfovibrionales	28221|Deltaproteobacteria	G	PFAM Cupin 2, conserved barrel	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
k59_167635_2	710685.MycrhN_0078	6.99e-09	57.8	COG1028@1|root,COG1028@2|Bacteria,2GW8A@201174|Actinobacteria,233Z6@1762|Mycobacteriaceae	201174|Actinobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
k59_228270_1	335543.Sfum_0208	1.07e-82	259.0	COG1008@1|root,COG1008@2|Bacteria,1MV7V@1224|Proteobacteria,42NGD@68525|delta/epsilon subdivisions,2WJDC@28221|Deltaproteobacteria,2MRBS@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M	-	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
k59_38888_1	443143.GM18_4016	5.88e-06	55.5	COG0642@1|root,COG3290@1|root,COG5002@1|root,COG2205@2|Bacteria,COG3290@2|Bacteria,COG5002@2|Bacteria,1NRP8@1224|Proteobacteria,42M0Y@68525|delta/epsilon subdivisions,2WIR4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,Hpt,PAS,PAS_9,Response_reg,SBP_bac_3
k59_137404_1	667014.Thein_1410	5.55e-18	83.2	COG0057@1|root,COG0057@2|Bacteria,2GGYS@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	G	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	-	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
k59_137404_2	667014.Thein_1409	5.9e-60	210.0	COG0574@1|root,COG3848@1|root,COG0574@2|Bacteria,COG3848@2|Bacteria,2GGWR@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	GT	Pyruvate phosphate dikinase, PEP/pyruvate binding domain	-	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PPDK_N
k59_213117_1	96561.Dole_1001	2.88e-48	171.0	COG1150@1|root,COG1150@2|Bacteria,1QUKA@1224|Proteobacteria,42MNE@68525|delta/epsilon subdivisions,2WIN3@28221|Deltaproteobacteria,2MHSC@213118|Desulfobacterales	28221|Deltaproteobacteria	C	4Fe-4S dicluster domain	qmoC	-	-	ko:K16887	-	-	-	-	ko00000	-	-	-	Fer4_17,Fer4_8,Fer4_9,Nitrate_red_gam
k59_175326_1	1084719.G3MAB9_9CAUD	2.69e-08	55.1	4QFGJ@10239|Viruses,4R0A2@35237|dsDNA viruses  no RNA stage,4QTCF@28883|Caudovirales,4QIHG@10662|Myoviridae	10662|Myoviridae	S	tRNA guanylyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_175326_3	1347086.CCBA010000019_gene1028	0.000997	45.1	COG1051@1|root,COG1051@2|Bacteria,1V3T8@1239|Firmicutes,4HH2F@91061|Bacilli,1ZGCQ@1386|Bacillus	91061|Bacilli	F	Belongs to the Nudix hydrolase family	-	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
k59_144949_1	933262.AXAM01000008_gene1975	1.08e-42	152.0	COG1652@1|root,COG1652@2|Bacteria,1MUBV@1224|Proteobacteria,42QS9@68525|delta/epsilon subdivisions,2WN3H@28221|Deltaproteobacteria,2MJ1W@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Peptidoglycan-binding LysM	-	-	-	-	-	-	-	-	-	-	-	-	LysM
k59_76915_1	1121405.dsmv_0938	2.42e-77	239.0	COG0548@1|root,COG0548@2|Bacteria,1MU17@1224|Proteobacteria,42N8G@68525|delta/epsilon subdivisions,2WKBC@28221|Deltaproteobacteria,2MI9G@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Belongs to the acetylglutamate kinase family. ArgB subfamily	argB	GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.2.8	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R02649	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
k59_182856_1	1167006.UWK_01323	9.61e-101	304.0	COG0498@1|root,COG0498@2|Bacteria,1MUWQ@1224|Proteobacteria,42M1W@68525|delta/epsilon subdivisions,2WK53@28221|Deltaproteobacteria,2MIJV@213118|Desulfobacterales	28221|Deltaproteobacteria	E	TIGRFAM threonine synthase	-	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
k59_38891_1	439235.Dalk_4908	2.01e-113	339.0	COG0407@1|root,COG0407@2|Bacteria,1R9IN@1224|Proteobacteria,42Q1Q@68525|delta/epsilon subdivisions,2WMDE@28221|Deltaproteobacteria,2MPE9@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	-	-	-	-	-	-	-	-	-	-	URO-D
k59_38891_2	644282.Deba_1650	1.78e-81	246.0	COG5012@1|root,COG5012@2|Bacteria,1PXID@1224|Proteobacteria,42R7Q@68525|delta/epsilon subdivisions,2WN2K@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Methionine synthase B12-binding module cap domain protein	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,B12-binding_2
k59_198042_1	561180.BIFGAL_03466	8.46e-17	85.9	COG0028@1|root,COG0028@2|Bacteria,2GKU4@201174|Actinobacteria,4CYR0@85004|Bifidobacteriales	201174|Actinobacteria	H	Thiamine pyrophosphate enzyme, central domain	ilvB	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
k59_107052_1	1304885.AUEY01000071_gene110	1.53e-30	125.0	COG4388@1|root,COG4388@2|Bacteria,1RA2J@1224|Proteobacteria,42S1P@68525|delta/epsilon subdivisions,2WNAJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Mu-like prophage I protein	-	-	-	-	-	-	-	-	-	-	-	-	Mu-like_Pro
k59_236039_1	472759.Nhal_0372	2.01e-102	306.0	COG1260@1|root,COG1260@2|Bacteria,1N0D9@1224|Proteobacteria,1RZ5M@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	Myo-inositol-1-phosphate synthase	-	-	5.5.1.4	ko:K01858	ko00521,ko00562,ko01100,ko01130,map00521,map00562,map01100,map01130	-	R07324	RC01804	ko00000,ko00001,ko01000	-	-	-	Inos-1-P_synth
k59_91918_1	880072.Desac_0293	1.58e-92	280.0	COG0568@1|root,COG0568@2|Bacteria,1MVWR@1224|Proteobacteria,42NRM@68525|delta/epsilon subdivisions,2WJ0S@28221|Deltaproteobacteria,2MQC3@213462|Syntrophobacterales	28221|Deltaproteobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	rpoH	-	-	ko:K03086,ko:K03089	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
k59_102459_2	1379281.AVAG01000031_gene106	6.51e-118	366.0	COG0506@1|root,COG1012@1|root,COG0506@2|Bacteria,COG1012@2|Bacteria,1MV93@1224|Proteobacteria,42MQH@68525|delta/epsilon subdivisions,2WJPV@28221|Deltaproteobacteria,2M8WP@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	Oxidizes proline to glutamate for use as a carbon and nitrogen source	putA	-	1.2.1.88,1.5.5.2	ko:K13821	ko00250,ko00330,ko01100,ko01110,ko01130,map00250,map00330,map01100,map01110,map01130	-	R00245,R00707,R00708,R01253,R04444,R04445,R05051	RC00080,RC00083,RC00216,RC00242,RC00255	ko00000,ko00001,ko01000,ko03000	-	-	iAF987.Gmet_3512	Aldedh,Pro_dh
k59_49038_1	105559.Nwat_2532	4.31e-44	160.0	COG0367@1|root,COG0367@2|Bacteria,1MW4E@1224|Proteobacteria,1RQ7D@1236|Gammaproteobacteria,1WWK7@135613|Chromatiales	1236|Gammaproteobacteria	F	Asparagine synthase, glutamine-hydrolyzing	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
k59_132779_1	1116369.KB890025_gene5095	1.5e-17	87.0	COG2186@1|root,COG2186@2|Bacteria,1R68P@1224|Proteobacteria,2U9AP@28211|Alphaproteobacteria,43KH0@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	K	FCD	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
k59_3228_1	335543.Sfum_0989	4.74e-91	278.0	COG0624@1|root,COG0624@2|Bacteria,1MVBR@1224|Proteobacteria,42MY5@68525|delta/epsilon subdivisions,2WKST@28221|Deltaproteobacteria,2MQY9@213462|Syntrophobacterales	28221|Deltaproteobacteria	E	Peptidase dimerisation domain	argE	-	3.5.1.16	ko:K01438	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R00669,R09107	RC00064,RC00300	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20
k59_3228_2	1121918.ARWE01000001_gene2427	3.84e-49	162.0	COG0454@1|root,COG0456@2|Bacteria,1RF31@1224|Proteobacteria,42RUB@68525|delta/epsilon subdivisions,2WN97@28221|Deltaproteobacteria,43UM1@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
k59_231412_2	1265505.ATUG01000002_gene1718	1.68e-46	165.0	COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,43AZ5@68525|delta/epsilon subdivisions,2X6DH@28221|Deltaproteobacteria,2MPHT@213118|Desulfobacterales	1224|Proteobacteria	KT	Bacterial regulatory protein, Fis family	-	-	-	ko:K06714	-	-	-	-	ko00000,ko03000	-	-	-	HTH_8,PAS_4,PAS_9,Sigma54_activat
k59_79718_1	580332.Slit_0598	4.39e-19	89.0	COG1766@1|root,COG1766@2|Bacteria,1MUQR@1224|Proteobacteria,2VI9M@28216|Betaproteobacteria,44V8S@713636|Nitrosomonadales	28216|Betaproteobacteria	N	The M ring may be actively involved in energy transduction	fliF	-	-	ko:K02409	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	YscJ_FliF,YscJ_FliF_C
k59_79718_2	933262.AXAM01000005_gene2526	5.67e-21	87.0	COG1677@1|root,COG1677@2|Bacteria,1NIFD@1224|Proteobacteria,42V59@68525|delta/epsilon subdivisions,2WSXK@28221|Deltaproteobacteria,2MM8C@213118|Desulfobacterales	28221|Deltaproteobacteria	N	Flagellar hook-basal body complex protein FliE	fliE	-	-	ko:K02408	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliE
k59_79718_3	264462.Bd3406	0.000195	42.4	COG1558@1|root,COG1558@2|Bacteria,1RHI3@1224|Proteobacteria,42TPI@68525|delta/epsilon subdivisions,2MT0U@213481|Bdellovibrionales,2WP1C@28221|Deltaproteobacteria	213481|Bdellovibrionales	N	Belongs to the flagella basal body rod proteins family	flgC	-	-	ko:K02388	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod,Flg_bbr_C
k59_117038_1	335543.Sfum_0104	2.06e-58	199.0	COG0445@1|root,COG0445@2|Bacteria,1MU6F@1224|Proteobacteria,42KZC@68525|delta/epsilon subdivisions,2WJ31@28221|Deltaproteobacteria,2MQ3V@213462|Syntrophobacterales	28221|Deltaproteobacteria	D	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34	gidA	GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363	-	ko:K03495	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko03016,ko03036	-	-	-	GIDA,GIDA_assoc
k59_133561_1	1304874.JAFY01000002_gene661	1.63e-47	163.0	COG0477@1|root,COG2814@2|Bacteria,3TACG@508458|Synergistetes	508458|Synergistetes	EGP	PFAM Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
k59_133561_2	335543.Sfum_1824	7.56e-74	227.0	COG0352@1|root,COG0352@2|Bacteria,1RDSU@1224|Proteobacteria,42R5Z@68525|delta/epsilon subdivisions,2WMPN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)	thiE	-	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	TMP-TENI
k59_26708_1	1232437.KL661978_gene3836	5.08e-46	160.0	COG0735@1|root,COG1918@1|root,COG0735@2|Bacteria,COG1918@2|Bacteria,1RDWJ@1224|Proteobacteria,42P61@68525|delta/epsilon subdivisions,2X5PQ@28221|Deltaproteobacteria,2MJ7H@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Belongs to the Fur family	-	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR,FeoA
k59_26708_2	1123371.ATXH01000041_gene680	7.36e-48	158.0	COG0735@1|root,COG0735@2|Bacteria,2GHTF@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	P	Belongs to the Fur family	-	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
k59_12380_1	1056495.Calag_1331	2.22e-52	175.0	COG0171@1|root,arCOG00069@2157|Archaea,2XQ3J@28889|Crenarchaeota	28889|Crenarchaeota	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source	nadE	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.1.5	ko:K01916	ko00760,ko01100,map00760,map01100	M00115	R00189	RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	NAD_synthase
k59_232195_1	1121413.JMKT01000017_gene361	6.9e-67	215.0	COG3842@1|root,COG3842@2|Bacteria,1QWPH@1224|Proteobacteria,43E0E@68525|delta/epsilon subdivisions,2X75F@28221|Deltaproteobacteria,2MHCG@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	PFAM ABC transporter related	-	-	3.6.3.55	ko:K06857	ko02010,map02010	M00186	R10531	RC00002	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.6.2,3.A.1.6.4	-	-	ABC_tran
k59_141163_1	765911.Thivi_0537	2.14e-120	360.0	COG4782@1|root,COG4782@2|Bacteria,1MVAD@1224|Proteobacteria,1S13M@1236|Gammaproteobacteria,1WWSG@135613|Chromatiales	135613|Chromatiales	S	PFAM Alpha beta hydrolase of	-	-	-	-	-	-	-	-	-	-	-	-	DUF900
k59_193490_1	439235.Dalk_1526	8.21e-73	245.0	COG0457@1|root,COG2114@1|root,COG3899@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG3899@2|Bacteria,1MUDT@1224|Proteobacteria,42NXT@68525|delta/epsilon subdivisions,2WIZ3@28221|Deltaproteobacteria,2MKIU@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,DZR,Guanylate_cyc,Pkinase,TPR_12
k59_201612_1	439235.Dalk_1775	4.14e-25	106.0	COG2197@1|root,COG2197@2|Bacteria,1R3YQ@1224|Proteobacteria,42WAE@68525|delta/epsilon subdivisions,2WRWH@28221|Deltaproteobacteria,2MPRG@213118|Desulfobacterales	28221|Deltaproteobacteria	K	PFAM Bacterial regulatory proteins, luxR family	-	-	-	-	-	-	-	-	-	-	-	-	GerE,PAS_9
k59_3675_1	637905.SVI_0891	4.42e-39	148.0	COG3267@1|root,COG3409@1|root,COG3267@2|Bacteria,COG3409@2|Bacteria,1MU3G@1224|Proteobacteria,1RMI0@1236|Gammaproteobacteria,2Q9JH@267890|Shewanellaceae	1236|Gammaproteobacteria	MU	PFAM Peptidoglycan-binding domain 1 protein	gspA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K02450	-	M00331	-	-	ko00000,ko00002,ko02044	9.B.42	-	-	AAA_22,PG_binding_1,T2SSB
k59_223974_1	1125863.JAFN01000001_gene3086	5.01e-36	136.0	COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,42P5W@68525|delta/epsilon subdivisions,2WMA6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM peptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
k59_186791_1	335543.Sfum_0824	3.01e-95	305.0	COG0493@1|root,COG1148@1|root,COG0493@2|Bacteria,COG1148@2|Bacteria,1MU2H@1224|Proteobacteria,42M6X@68525|delta/epsilon subdivisions,2X6YD@28221|Deltaproteobacteria,2MQTQ@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.17.1.10,1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388,ko:K15022	ko00680,ko00720,ko01100,ko01120,ko01200,map00680,map00720,map01100,map01120,map01200	M00356,M00357,M00377,M00563,M00567	R00134,R04540,R11928,R11931,R11943,R11944	RC00011,RC02796	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_20,Pyr_redox_2
k59_41872_1	1232410.KI421415_gene3114	3.24e-45	151.0	COG0817@1|root,COG0817@2|Bacteria,1MUJI@1224|Proteobacteria,42QPX@68525|delta/epsilon subdivisions,2WNF9@28221|Deltaproteobacteria,43SHA@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	Crossover junction endodeoxyribonuclease RuvC	ruvC	GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576	3.1.22.4	ko:K01159	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvC
k59_178324_1	930169.B5T_02253	2.72e-54	179.0	COG3897@1|root,COG3897@2|Bacteria,1RJUI@1224|Proteobacteria,1S6V9@1236|Gammaproteobacteria,1XKCT@135619|Oceanospirillales	135619|Oceanospirillales	S	COG2230 Cyclopropane fatty acid synthase and related methyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_16,Methyltransf_25
k59_193495_1	1121405.dsmv_1300	1.34e-125	370.0	COG1472@1|root,COG1472@2|Bacteria,1MVAJ@1224|Proteobacteria,42N8K@68525|delta/epsilon subdivisions,2WN0Z@28221|Deltaproteobacteria,2MHV6@213118|Desulfobacterales	28221|Deltaproteobacteria	G	PFAM glycoside hydrolase family 3 domain protein	-	-	3.2.1.52	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	M00628	R00022,R05963,R07809,R07810,R10831	RC00049	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyco_hydro_3,Glyco_hydro_3_C
k59_110692_1	1304872.JAGC01000009_gene959	2.39e-57	201.0	COG0577@1|root,COG2234@1|root,COG0577@2|Bacteria,COG2234@2|Bacteria,1MVYE@1224|Proteobacteria,42PKN@68525|delta/epsilon subdivisions,2WIWP@28221|Deltaproteobacteria,2M8ZJ@213115|Desulfovibrionales	28221|Deltaproteobacteria	V	FtsX-like permease family	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,PA,Peptidase_M28
k59_163291_1	926569.ANT_26970	1.85e-15	81.6	COG2010@1|root,COG2864@1|root,COG2010@2|Bacteria,COG2864@2|Bacteria	2|Bacteria	C	formate dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_c3_2,Ni_hydr_CYTB,PSCyt1
k59_178327_1	521011.Mpal_1345	6.84e-06	54.3	COG0614@1|root,arCOG03561@1|root,arCOG03561@2157|Archaea,arCOG03611@2157|Archaea,2Y1Q9@28890|Euryarchaeota,2N9M9@224756|Methanomicrobia	224756|Methanomicrobia	P	PFAM NHL repeat containing protein	-	-	-	-	-	-	-	-	-	-	-	-	FlgD_ig,NHL
k59_103105_1	203275.BFO_0886	2.13e-12	73.6	COG3210@1|root,COG3210@2|Bacteria	2|Bacteria	U	domain, Protein	-	-	-	ko:K09800	-	-	-	-	ko00000,ko02000	-	-	-	Big_2,LRR_5,LXG,Laminin_G_3,SLH
k59_19351_1	335543.Sfum_1935	1.19e-67	220.0	COG1007@1|root,COG1007@2|Bacteria,1MV56@1224|Proteobacteria,42P7Z@68525|delta/epsilon subdivisions,2WKS0@28221|Deltaproteobacteria,2MQ9R@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
k59_216533_1	1121447.JONL01000002_gene2044	3.93e-36	139.0	COG2208@1|root,COG2972@1|root,COG2208@2|Bacteria,COG2972@2|Bacteria,1RCHY@1224|Proteobacteria,42R1G@68525|delta/epsilon subdivisions,2WMR7@28221|Deltaproteobacteria,2M83U@213115|Desulfovibrionales	28221|Deltaproteobacteria	KT	SMART protein phosphatase 2C domain protein	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	HAMP,SpoIIE
k59_156289_1	634956.Geoth_3417	1.45e-49	183.0	COG1657@1|root,COG1785@1|root,COG1657@2|Bacteria,COG1785@2|Bacteria,1TQCI@1239|Firmicutes,4HA27@91061|Bacilli,1WHWT@129337|Geobacillus	91061|Bacilli	P	Belongs to the alkaline phosphatase family	phoB	-	3.1.3.1	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	M00126	R02135,R04620	RC00017	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	-	-	-	Alk_phosphatase
k59_87645_1	573370.DMR_12550	1.39e-81	260.0	COG0642@1|root,COG2205@2|Bacteria,1QHXX@1224|Proteobacteria,42NW1@68525|delta/epsilon subdivisions,2WJUF@28221|Deltaproteobacteria,2M85B@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	PFAM ATP-binding region ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
k59_171297_1	177437.HRM2_10920	4.79e-17	79.7	COG0735@1|root,COG1918@1|root,COG0735@2|Bacteria,COG1918@2|Bacteria,1RDWJ@1224|Proteobacteria,42P61@68525|delta/epsilon subdivisions,2X5PQ@28221|Deltaproteobacteria,2MJ7H@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Belongs to the Fur family	-	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR,FeoA
k59_171297_2	371731.Rsw2DRAFT_3172	9.01e-10	57.0	COG1918@1|root,COG1918@2|Bacteria,1NH7U@1224|Proteobacteria,2UJG2@28211|Alphaproteobacteria,1FD2D@1060|Rhodobacter	28211|Alphaproteobacteria	P	FeoA	-	-	-	ko:K04758	-	-	-	-	ko00000,ko02000	-	-	-	FeoA
k59_57750_1	177437.HRM2_11850	4.97e-84	276.0	COG1148@1|root,COG1148@2|Bacteria,1QUM4@1224|Proteobacteria,42MPP@68525|delta/epsilon subdivisions,2WJ3U@28221|Deltaproteobacteria,2MIJ3@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM Pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_6,Pyr_redox_2
k59_117687_2	933262.AXAM01000001_gene386	5.49e-19	81.6	COG0236@1|root,COG0236@2|Bacteria,1N6RU@1224|Proteobacteria,42V26@68525|delta/epsilon subdivisions,2WS9W@28221|Deltaproteobacteria,2MKVI@213118|Desulfobacterales	28221|Deltaproteobacteria	IQ	Phosphopantetheine attachment site	-	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
k59_117687_3	1218084.BBJK01000007_gene1075	7.98e-09	56.2	COG1028@1|root,COG1028@2|Bacteria,1R413@1224|Proteobacteria,2VIW6@28216|Betaproteobacteria,1K2S8@119060|Burkholderiaceae	28216|Betaproteobacteria	IQ	Short-chain dehydrogenase reductase sdr	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
k59_239023_1	1121405.dsmv_1465	2.83e-125	367.0	COG0665@1|root,COG0665@2|Bacteria,1PHGK@1224|Proteobacteria,42YCR@68525|delta/epsilon subdivisions,2X5HV@28221|Deltaproteobacteria,2MMNP@213118|Desulfobacterales	28221|Deltaproteobacteria	E	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
k59_87653_2	933262.AXAM01000008_gene1932	8.64e-18	85.9	COG1921@1|root,COG1921@2|Bacteria,1MWXI@1224|Proteobacteria,42MU7@68525|delta/epsilon subdivisions,2WJFQ@28221|Deltaproteobacteria,2MIIC@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis	selA	GO:0003674,GO:0003824,GO:0004125,GO:0006139,GO:0006399,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016740,GO:0016785,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034654,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097056,GO:0140098,GO:0140101,GO:1901360,GO:1901362,GO:1901576	2.9.1.1	ko:K01042	ko00450,ko00970,map00450,map00970	-	R08219	RC01246	ko00000,ko00001,ko01000	-	-	-	Se-cys_synth_N,SelA
k59_156293_1	1121448.DGI_0750	1.29e-65	204.0	COG1592@1|root,COG1592@2|Bacteria,1R9WG@1224|Proteobacteria,42RFX@68525|delta/epsilon subdivisions,2WN92@28221|Deltaproteobacteria,2M9VS@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	PFAM Rubrerythrin	-	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
k59_223991_2	1268068.PG5_31870	1.8e-14	78.6	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,1RNBG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
k59_147931_1	1379698.RBG1_1C00001G1654	1.56e-99	305.0	COG0606@1|root,COG0606@2|Bacteria,2NNW7@2323|unclassified Bacteria	2|Bacteria	O	Magnesium chelatase, subunit ChlI C-terminal	comM	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
k59_103109_1	909663.KI867150_gene2871	1.02e-122	368.0	COG3039@1|root,COG3039@2|Bacteria,1QY2X@1224|Proteobacteria	1224|Proteobacteria	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_6
k59_57764_1	335543.Sfum_0065	5.28e-111	334.0	COG1220@1|root,COG1220@2|Bacteria,1MVK9@1224|Proteobacteria,42M48@68525|delta/epsilon subdivisions,2WISV@28221|Deltaproteobacteria,2MQ63@213462|Syntrophobacterales	28221|Deltaproteobacteria	O	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis	hslU	-	-	ko:K03667	-	-	-	-	ko00000,ko03110	-	-	-	AAA_2,ClpB_D2-small
k59_141187_2	1304885.AUEY01000085_gene2476	2.43e-92	281.0	COG1744@1|root,COG1744@2|Bacteria,1MWTM@1224|Proteobacteria,42NPH@68525|delta/epsilon subdivisions,2WIXM@28221|Deltaproteobacteria,2MPSE@213118|Desulfobacterales	28221|Deltaproteobacteria	M	ABC transporter substrate-binding protein PnrA-like	-	-	-	ko:K02058	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	Bmp
k59_64779_1	1121448.DGI_0077	4.16e-31	129.0	COG4972@1|root,COG4972@2|Bacteria,1RCKF@1224|Proteobacteria,42R0T@68525|delta/epsilon subdivisions,2WMSI@28221|Deltaproteobacteria,2MA86@213115|Desulfovibrionales	28221|Deltaproteobacteria	NU	Pilus assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	PilM_2
k59_223997_1	1504672.669784321	2.04e-07	50.8	COG0745@1|root,COG0745@2|Bacteria,1RHCU@1224|Proteobacteria,2VT7U@28216|Betaproteobacteria,4AEF6@80864|Comamonadaceae	28216|Betaproteobacteria	T	Response regulator receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
k59_223997_2	96561.Dole_1669	8.56e-40	137.0	COG2203@1|root,COG2203@2|Bacteria,1NBYK@1224|Proteobacteria,42NFX@68525|delta/epsilon subdivisions,2WM8H@28221|Deltaproteobacteria,2MIRU@213118|Desulfobacterales	28221|Deltaproteobacteria	T	PFAM GAF domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2
k59_141192_1	1121918.ARWE01000001_gene1341	2.82e-28	115.0	COG2203@1|root,COG3605@1|root,COG2203@2|Bacteria,COG3605@2|Bacteria,1R8AK@1224|Proteobacteria,42MTP@68525|delta/epsilon subdivisions,2WIST@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	PFAM GAF domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2
k59_34967_1	1385935.N836_22570	3.13e-22	93.2	COG3350@1|root,COG3350@2|Bacteria,1G6RV@1117|Cyanobacteria,1HBTF@1150|Oscillatoriales	1117|Cyanobacteria	S	Yhs domain-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	YHS
k59_209446_1	997296.PB1_07987	2.34e-11	62.4	COG2204@1|root,COG2204@2|Bacteria,1V6R9@1239|Firmicutes,4HIXH@91061|Bacilli,1ZG9M@1386|Bacillus	91061|Bacilli	T	response regulator	spo0F	-	-	ko:K02490	ko02020,ko02024,map02020,map02024	M00485	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg
k59_64790_2	589865.DaAHT2_2128	1.95e-16	73.9	2ED51@1|root,3371S@2|Bacteria,1P2UH@1224|Proteobacteria,43180@68525|delta/epsilon subdivisions,2WWP0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_3703_1	90814.KL370891_gene1641	3.42e-46	160.0	COG2826@1|root,COG2826@2|Bacteria,1MWI0@1224|Proteobacteria,1RRSE@1236|Gammaproteobacteria,462DI@72273|Thiotrichales	72273|Thiotrichales	L	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_38,rve
k59_87661_1	877411.JMMA01000002_gene401	8.93e-07	53.9	COG0317@1|root,COG0317@2|Bacteria,1TNYZ@1239|Firmicutes,2489A@186801|Clostridia,3WGUK@541000|Ruminococcaceae	186801|Clostridia	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	relA	-	2.7.6.5	ko:K00951	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS16615	ACT_4,HD_4,RelA_SpoT,TGS
k59_87661_2	190304.FN0986	4.31e-30	119.0	COG0150@1|root,COG0150@2|Bacteria,378FU@32066|Fusobacteria	32066|Fusobacteria	F	Phosphoribosylformylglycinamidine cyclo-ligase	purM	-	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
k59_95498_1	395493.BegalDRAFT_1942	3.6e-111	341.0	COG4166@1|root,COG4166@2|Bacteria,1MUVU@1224|Proteobacteria,1RMA1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	ABC-type oligopeptide transport system, periplasmic component	yejA	-	-	ko:K02035,ko:K13893	ko02010,ko02024,map02010,map02024	M00239,M00349	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.21,3.A.1.5.24	-	-	SBP_bac_5
k59_147943_1	420246.GTNG_2830	1.52e-33	124.0	2DRIA@1|root,33BX1@2|Bacteria,1VY3D@1239|Firmicutes,4HX43@91061|Bacilli,1WHEN@129337|Geobacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_141197_1	880073.Calab_2107	1.93e-116	342.0	COG2801@1|root,COG2801@2|Bacteria	2|Bacteria	L	transposition	-	-	2.7.7.49	ko:K00986,ko:K07497	-	-	-	-	ko00000,ko01000	-	-	-	HTH_32,rve,rve_3
k59_126038_1	933262.AXAM01000090_gene2620	9.1e-88	282.0	COG0643@1|root,COG0643@2|Bacteria,1MUAG@1224|Proteobacteria,42M6Q@68525|delta/epsilon subdivisions,2WJ5U@28221|Deltaproteobacteria,2MIXJ@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Signal transducing histidine kinase, homodimeric	-	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt,Response_reg
k59_117719_1	1267535.KB906767_gene1013	1.1e-46	166.0	COG0621@1|root,COG0621@2|Bacteria,3Y362@57723|Acidobacteria,2JIYW@204432|Acidobacteriia	204432|Acidobacteriia	H	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12	rimO	-	2.8.4.4	ko:K14441	-	-	R10652	RC00003,RC03217	ko00000,ko01000,ko03009	-	-	-	Radical_SAM,UPF0004
k59_209454_1	1265505.ATUG01000002_gene1978	1.24e-06	48.5	2ABIE@1|root,310ZN@2|Bacteria,1RFY1@1224|Proteobacteria,42RKZ@68525|delta/epsilon subdivisions,2WNKN@28221|Deltaproteobacteria,2MM46@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF3795)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3795
k59_209454_2	1232437.KL661956_gene2417	1.71e-95	287.0	COG4977@1|root,COG4977@2|Bacteria,1MUDK@1224|Proteobacteria,42QRG@68525|delta/epsilon subdivisions,2WJ5Z@28221|Deltaproteobacteria,2MIYW@213118|Desulfobacterales	28221|Deltaproteobacteria	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	DJ-1_PfpI,HTH_18
k59_80471_1	1244869.H261_19918	2.19e-90	293.0	COG0243@1|root,COG0243@2|Bacteria,1NR6J@1224|Proteobacteria,2TSAP@28211|Alphaproteobacteria,2JRAB@204441|Rhodospirillales	204441|Rhodospirillales	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Molybdopterin,Molydop_binding
k59_117721_1	1232437.KL661965_gene3270	2.68e-146	430.0	COG2414@1|root,COG2414@2|Bacteria,1MWBB@1224|Proteobacteria,42NR7@68525|delta/epsilon subdivisions,2WK49@28221|Deltaproteobacteria,2MJNF@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Aldehyde ferredoxin oxidoreductase	-	-	1.2.7.5	ko:K03738	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00309	R08571	RC00242	ko00000,ko00001,ko00002,ko01000	-	-	-	AFOR_C,AFOR_N
k59_171330_1	1123514.KB905899_gene1022	5.77e-72	240.0	COG0188@1|root,COG0188@2|Bacteria,1MUGG@1224|Proteobacteria,1RN03@1236|Gammaproteobacteria,45ZYT@72273|Thiotrichales	72273|Thiotrichales	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
k59_95511_1	981369.JQMJ01000001_gene6815	3.09e-39	145.0	COG3547@1|root,COG3547@2|Bacteria,2IBF5@201174|Actinobacteria	201174|Actinobacteria	L	Transposase IS116 IS110 IS902 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_81614_1	1307759.JOMJ01000003_gene709	2.83e-74	238.0	COG1541@1|root,COG1541@2|Bacteria,1MV1W@1224|Proteobacteria,42KZ5@68525|delta/epsilon subdivisions,2WKK2@28221|Deltaproteobacteria,2M9Z6@213115|Desulfovibrionales	28221|Deltaproteobacteria	H	AMP-binding enzyme	-	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C_2
k59_157902_1	1307759.JOMJ01000004_gene2697	3.46e-113	335.0	COG1060@1|root,COG1060@2|Bacteria,1MX50@1224|Proteobacteria,42M6U@68525|delta/epsilon subdivisions,2WJ6Y@28221|Deltaproteobacteria,2M8I4@213115|Desulfovibrionales	28221|Deltaproteobacteria	H	Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnC	-	1.21.98.1	ko:K11784	ko00130,ko01110,map00130,map01110	-	R08588	RC02329	ko00000,ko00001,ko01000	-	-	-	Radical_SAM
k59_135446_1	485918.Cpin_2419	8.94e-29	115.0	COG0073@1|root,COG0073@2|Bacteria,4P176@976|Bacteroidetes,1IWP0@117747|Sphingobacteriia	976|Bacteroidetes	J	RNA ligase	-	-	-	-	-	-	-	-	-	-	-	-	RNA_ligase
k59_135446_4	1123252.ATZF01000009_gene612	7.02e-21	90.5	COG4021@1|root,COG4021@2|Bacteria,1V7KD@1239|Firmicutes,4HT6X@91061|Bacilli	91061|Bacilli	S	tRNAHis guanylyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Thg1
k59_211197_1	1254432.SCE1572_04165	2.23e-31	130.0	COG0515@1|root,COG0642@1|root,COG0745@1|root,COG2203@1|root,COG3899@1|root,COG0515@2|Bacteria,COG0745@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,COG3899@2|Bacteria,1NRP8@1224|Proteobacteria,42M0Y@68525|delta/epsilon subdivisions,2WKF3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GAF_2,HATPase_c,HisKA,PAS_4,Pkinase,Response_reg
k59_14279_1	1121396.KB893111_gene1916	2.04e-09	63.2	COG3437@1|root,COG3437@2|Bacteria,1MUB8@1224|Proteobacteria,42QEF@68525|delta/epsilon subdivisions,2WJJN@28221|Deltaproteobacteria,2MJVU@213118|Desulfobacterales	28221|Deltaproteobacteria	T	HD domain	-	-	-	ko:K07814	-	-	-	-	ko00000,ko02022	-	-	-	HD,HD_5,Response_reg
k59_172939_1	1519464.HY22_00075	3.61e-34	135.0	COG2203@1|root,COG4191@1|root,COG2203@2|Bacteria,COG4191@2|Bacteria,1FEZK@1090|Chlorobi	1090|Chlorobi	T	SMART PAS domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4,PAS_9,Response_reg
k59_172946_1	1214217.ALNF01000013_gene555	6.31e-55	185.0	COG0372@1|root,COG0372@2|Bacteria,1TPPS@1239|Firmicutes,4H9YE@91061|Bacilli,1WTCR@1307|Streptococcus suis	91061|Bacilli	C	Citrate synthase, C-terminal domain	citZ	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
k59_104912_1	706587.Desti_2244	3.58e-62	204.0	COG1902@1|root,COG1902@2|Bacteria,1R4A8@1224|Proteobacteria,42YBR@68525|delta/epsilon subdivisions,2WU33@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	NADH flavin oxidoreductase NADH oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_FMN
k59_157915_1	1046714.AMRX01000001_gene1780	3.57e-05	47.8	COG0642@1|root,COG0784@1|root,COG1457@1|root,COG0784@2|Bacteria,COG1457@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,1RRGT@1236|Gammaproteobacteria,464VX@72275|Alteromonadaceae	1236|Gammaproteobacteria	T	COG0642 Signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
k59_157915_2	1089548.KI783301_gene1141	6.25e-11	65.1	COG0745@1|root,COG0745@2|Bacteria,1TS81@1239|Firmicutes,4HEGD@91061|Bacilli	91061|Bacilli	T	Transcriptional regulator	mprA1	-	-	ko:K07669	ko02020,map02020	M00460	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
k59_180088_2	1265505.ATUG01000001_gene4443	4.06e-17	80.9	COG0591@1|root,COG0591@2|Bacteria,1MUBI@1224|Proteobacteria,42N9T@68525|delta/epsilon subdivisions,2X85G@28221|Deltaproteobacteria,2MNKJ@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Sodium:solute symporter family	-	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
k59_211211_1	1167006.UWK_02670	9.4e-22	94.7	COG0477@1|root,COG2814@2|Bacteria,1R9V9@1224|Proteobacteria,42Q1C@68525|delta/epsilon subdivisions,2WK7P@28221|Deltaproteobacteria,2MMQA@213118|Desulfobacterales	28221|Deltaproteobacteria	EGP	Major Facilitator Superfamily	-	-	-	ko:K02575	ko00910,map00910	M00615	-	-	ko00000,ko00001,ko00002,ko02000	2.A.1.8	-	-	MFS_1
k59_5228_1	876269.ARWA01000001_gene1847	2.9e-70	221.0	COG4089@1|root,COG4089@2|Bacteria,1MV8K@1224|Proteobacteria,2U3GA@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Protein of unknown function (DUF1614)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1614
k59_21025_1	525897.Dbac_1343	2.16e-69	232.0	COG0653@1|root,COG0653@2|Bacteria,1MUJZ@1224|Proteobacteria,42MMV@68525|delta/epsilon subdivisions,2WIZ4@28221|Deltaproteobacteria,2M8H9@213115|Desulfovibrionales	28221|Deltaproteobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	-	-	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	SecA_DEAD,SecA_PP_bind
k59_36678_1	469596.HMPREF9488_02206	7.92e-22	95.9	COG0042@1|root,COG0042@2|Bacteria,1TQ2R@1239|Firmicutes,3VPA3@526524|Erysipelotrichia	526524|Erysipelotrichia	J	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	-	-	-	-	-	-	-	-	-	-	-	-	Dus
k59_240960_1	903818.KI912268_gene3327	6.19e-33	127.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cyt_bd_oxida_I,Cytochrome_CBB3
k59_142984_1	443144.GM21_2305	1.11e-71	239.0	COG1200@1|root,COG1200@2|Bacteria,1MWN2@1224|Proteobacteria,42NF8@68525|delta/epsilon subdivisions,2WKBA@28221|Deltaproteobacteria,43TAY@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
k59_112493_1	1121935.AQXX01000144_gene4379	3.39e-30	124.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,1XHXU@135619|Oceanospirillales	135619|Oceanospirillales	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_172958_1	1304888.ATWF01000001_gene657	7.98e-22	96.3	COG0248@1|root,COG0248@2|Bacteria,2GFEH@200930|Deferribacteres	200930|Deferribacteres	FP	Ppx/GppA phosphatase family	-	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	Ppx-GppA
k59_172958_2	880072.Desac_0657	2.53e-45	160.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,1MUJM@1224|Proteobacteria,42M2M@68525|delta/epsilon subdivisions,2WJ5H@28221|Deltaproteobacteria,2MQ5B@213462|Syntrophobacterales	28221|Deltaproteobacteria	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	guaB	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH,NMO
k59_5229_3	318161.Sden_0310	5.85e-12	66.6	COG1743@1|root,COG1743@2|Bacteria,1P7I6@1224|Proteobacteria,1RMB6@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	COG0863 DNA modification methylase	-	-	-	-	-	-	-	-	-	-	-	-	N6_N4_Mtase
k59_225810_1	1123373.ATXI01000020_gene1243	1.57e-46	156.0	COG1898@1|root,COG1898@2|Bacteria,2GHU3@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	M	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose	-	-	5.1.3.13	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R06514	RC01531	ko00000,ko00001,ko00002,ko01000	-	-	-	dTDP_sugar_isom
k59_225810_2	1123372.AUIT01000018_gene1408	7.57e-26	108.0	COG0451@1|root,COG0451@2|Bacteria,2GHYT@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	M	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	GDP_Man_Dehyd
k59_149694_2	1232437.KL662069_gene1815	6.06e-25	100.0	COG0778@1|root,COG0778@2|Bacteria,1RJMP@1224|Proteobacteria,43BDS@68525|delta/epsilon subdivisions,2X6SC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
k59_164955_1	1191523.MROS_2322	2.42e-65	208.0	COG2801@1|root,COG2801@2|Bacteria	2|Bacteria	L	transposition	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,HTH_Tnp_1,rve,rve_3
k59_119515_1	1410618.JNKI01000003_gene2497	2.98e-60	192.0	COG0097@1|root,COG0097@2|Bacteria,1V1FC@1239|Firmicutes,4H3Z2@909932|Negativicutes	909932|Negativicutes	J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center	rplF	-	-	ko:K02933	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L6
k59_157931_1	1125863.JAFN01000001_gene763	7.16e-42	152.0	COG0287@1|root,COG0287@2|Bacteria,1QTZA@1224|Proteobacteria,42MH0@68525|delta/epsilon subdivisions,2WJZ7@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Prephenate dehydrogenase	-	-	1.3.1.12	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00025	R01728	RC00125	ko00000,ko00001,ko00002,ko01000	-	-	-	PDH
k59_172966_1	933262.AXAM01000018_gene976	5.63e-98	301.0	COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,42NEU@68525|delta/epsilon subdivisions,2WM5E@28221|Deltaproteobacteria,2MMZP@213118|Desulfobacterales	28221|Deltaproteobacteria	KT	Bacterial regulatory protein, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Sigma54_activat
k59_164960_1	1167006.UWK_02920	6.02e-54	183.0	COG0664@1|root,COG0664@2|Bacteria,1NIIC@1224|Proteobacteria,42XDM@68525|delta/epsilon subdivisions,2WSZ2@28221|Deltaproteobacteria,2MN5S@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Domain of unknown function (DUF4388)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388,cNMP_binding
k59_135503_1	1121440.AUMA01000001_gene88	3.89e-37	142.0	COG1001@1|root,COG1001@2|Bacteria,1MVFP@1224|Proteobacteria,42NWX@68525|delta/epsilon subdivisions,2WIZY@28221|Deltaproteobacteria,2M9QV@213115|Desulfovibrionales	28221|Deltaproteobacteria	F	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family	ade	-	3.5.4.2	ko:K01486	ko00230,ko01100,map00230,map01100	-	R01244	RC00477	ko00000,ko00001,ko01000	-	-	-	Adenine_deam_C,Amidohydro_1
k59_74422_1	1232410.KI421426_gene1390	6.61e-36	133.0	COG2271@1|root,COG2271@2|Bacteria,1PND6@1224|Proteobacteria,42RJK@68525|delta/epsilon subdivisions,2WNEM@28221|Deltaproteobacteria,43UWP@69541|Desulfuromonadales	28221|Deltaproteobacteria	G	PFAM major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
k59_203430_1	203124.Tery_0258	1.68e-31	125.0	COG1446@1|root,COG1446@2|Bacteria,1G0G5@1117|Cyanobacteria,1H7SV@1150|Oscillatoriales	1117|Cyanobacteria	E	PFAM peptidase T2 asparaginase 2	-	-	3.4.19.5,3.5.1.1	ko:K01424,ko:K13051	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	-	R00485	RC00010,RC02798	ko00000,ko00001,ko01000,ko01002	-	-	-	Asparaginase_2
k59_172975_1	696281.Desru_1139	2.05e-14	75.9	COG2264@1|root,COG2264@2|Bacteria,1TPKI@1239|Firmicutes,247VY@186801|Clostridia,260D2@186807|Peptococcaceae	186801|Clostridia	J	Methylates ribosomal protein L11	prmA	-	-	ko:K02687	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PrmA
k59_89644_1	671065.MetMK1DRAFT_00021710	0.0006	41.2	COG0096@1|root,arCOG04091@2157|Archaea,2XQCX@28889|Crenarchaeota	28889|Crenarchaeota	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit	rps8	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02994	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S8
k59_89644_2	1184251.TCELL_0339	8.63e-31	114.0	COG0094@1|root,arCOG04092@2157|Archaea,2XQDJ@28889|Crenarchaeota	28889|Crenarchaeota	J	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits	rpl5	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02931	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L5,Ribosomal_L5_C
k59_218295_1	795359.TOPB45_0831	1.79e-65	209.0	COG0639@1|root,COG0639@2|Bacteria,2GHP8@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	T	Calcineurin-like phosphoesterase	-	-	3.1.3.16	ko:K07313	-	-	-	-	ko00000,ko01000	-	-	-	Metallophos
k59_135511_1	439235.Dalk_2830	4.88e-95	295.0	COG2208@1|root,COG2972@1|root,COG2208@2|Bacteria,COG2972@2|Bacteria,1R7WZ@1224|Proteobacteria,42Q3R@68525|delta/epsilon subdivisions,2WM5A@28221|Deltaproteobacteria,2MIDF@213118|Desulfobacterales	28221|Deltaproteobacteria	KT	Sigma factor PP2C-like phosphatases	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	GAF_2,SSF,SpoIIE
k59_164967_1	742738.HMPREF9460_01571	1.35e-09	59.7	COG3874@1|root,COG3874@2|Bacteria,1V6H7@1239|Firmicutes,24JJ5@186801|Clostridia,2699N@186813|unclassified Clostridiales	186801|Clostridia	S	Sporulation protein YtfJ (Spore_YtfJ)	ytfJ	-	-	-	-	-	-	-	-	-	-	-	Spore_YtfJ
k59_66483_1	1121451.DESAM_21772	1.45e-57	188.0	COG1102@1|root,COG1102@2|Bacteria,1R4GX@1224|Proteobacteria,42QKV@68525|delta/epsilon subdivisions,2WJS2@28221|Deltaproteobacteria,2MC69@213115|Desulfovibrionales	28221|Deltaproteobacteria	F	Cytidylate kinase-like family	-	-	-	-	-	-	-	-	-	-	-	-	Cytidylate_kin2
k59_188580_1	1499967.BAYZ01000067_gene6050	2.38e-127	368.0	COG0656@1|root,COG0656@2|Bacteria,2NPBV@2323|unclassified Bacteria	2|Bacteria	S	Aldo/keto reductase family	-	-	1.1.1.346	ko:K06221	-	-	R08878	RC00089	ko00000,ko01000	-	-	-	Aldo_ket_red
k59_225820_1	1054217.TALC_00783	2.6e-16	79.3	COG0454@1|root,arCOG00826@2157|Archaea,2Y1KX@28890|Euryarchaeota	28890|Euryarchaeota	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
k59_143021_1	525146.Ddes_2317	6.96e-10	58.9	COG0389@1|root,COG0389@2|Bacteria,1MUUH@1224|Proteobacteria,42NGG@68525|delta/epsilon subdivisions,2WIVT@28221|Deltaproteobacteria,2M80Z@213115|Desulfovibrionales	28221|Deltaproteobacteria	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	dinB	-	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
k59_143021_2	1121405.dsmv_0666	2.61e-47	166.0	COG3604@1|root,COG3604@2|Bacteria,1QTT3@1224|Proteobacteria,42Y69@68525|delta/epsilon subdivisions,2WJ5F@28221|Deltaproteobacteria,2MI66@213118|Desulfobacterales	28221|Deltaproteobacteria	KT	PFAM sigma-54 factor interaction domain-containing protein	-	-	-	ko:K02584	ko02020,map02020	-	-	-	ko00000,ko00001,ko03000	-	-	-	GAF,GAF_2,HTH_8,Sigma54_activat
k59_203446_1	439235.Dalk_5089	6.18e-150	439.0	COG1894@1|root,COG1894@2|Bacteria,1MV8F@1224|Proteobacteria,42N6N@68525|delta/epsilon subdivisions,2WJ1W@28221|Deltaproteobacteria,2MJ8N@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Respiratory-chain NADH dehydrogenase domain 51 kDa subunit	-	-	1.6.5.3	ko:K00124,ko:K00335	ko00190,ko00630,ko00680,ko01100,ko01120,ko01200,map00190,map00630,map00680,map01100,map01120,map01200	M00144	R00519,R11945	RC00061,RC02796	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx,Complex1_51K,Fer4,NADH_4Fe-4S,SLBB
k59_203446_2	439235.Dalk_5090	1.3e-29	116.0	COG1018@1|root,COG1148@1|root,COG1018@2|Bacteria,COG1148@2|Bacteria,1QUM4@1224|Proteobacteria,42MPP@68525|delta/epsilon subdivisions,2WJ3U@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	4Fe-4S ferredoxin iron-sulfur binding domain protein	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_4,Fer4_7,Pyr_redox_2
k59_59658_2	1254432.SCE1572_04480	1.92e-19	91.3	COG1716@1|root,COG2203@1|root,COG3829@1|root,COG1716@2|Bacteria,COG2203@2|Bacteria,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,43BKG@68525|delta/epsilon subdivisions,2X6YI@28221|Deltaproteobacteria,2YZGR@29|Myxococcales	28221|Deltaproteobacteria	KT	Sigma-54 interaction domain	-	-	-	ko:K02584	ko02020,map02020	-	-	-	ko00000,ko00001,ko03000	-	-	-	FHA,GAF,GAF_2,HTH_8,Sigma54_activat,Yop-YscD_cpl
k59_211240_1	909663.KI867151_gene3059	3.33e-40	144.0	COG0583@1|root,COG0583@2|Bacteria,1MWVU@1224|Proteobacteria	1224|Proteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
k59_43582_1	1123234.AUKI01000016_gene2917	8.42e-20	88.6	COG1646@1|root,COG1646@2|Bacteria,4NER8@976|Bacteroidetes,1HYFZ@117743|Flavobacteriia	976|Bacteroidetes	I	Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P)	pcrB	-	-	ko:K07094	-	-	-	-	ko00000,ko01000	-	-	-	PcrB
k59_14311_1	926566.Terro_3122	1.94e-35	139.0	COG4974@1|root,COG4974@2|Bacteria,3Y4UM@57723|Acidobacteria,2JJEI@204432|Acidobacteriia	204432|Acidobacteriia	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_1,Phage_integrase
k59_14311_2	445961.IW15_01185	6.81e-07	56.6	COG0582@1|root,COG0582@2|Bacteria,4NJTA@976|Bacteroidetes,1I3BX@117743|Flavobacteriia,3ZT40@59732|Chryseobacterium	976|Bacteroidetes	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
k59_218305_1	1121405.dsmv_1660	5.22e-76	236.0	COG2010@1|root,COG2993@1|root,COG2010@2|Bacteria,COG2993@2|Bacteria,1MXEY@1224|Proteobacteria,42NZG@68525|delta/epsilon subdivisions,2WNX9@28221|Deltaproteobacteria,2MKZC@213118|Desulfobacterales	28221|Deltaproteobacteria	C	cytochrome C oxidase mono-heme subunit FixO	-	-	-	ko:K00405	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	Cytochrome_CBB3,FixO
k59_89668_1	1123508.JH636452_gene7010	3.04e-59	195.0	COG0515@1|root,COG0515@2|Bacteria,2IZFV@203682|Planctomycetes	203682|Planctomycetes	KLT	serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_211245_1	1297742.A176_01509	1.1e-10	63.5	COG0484@1|root,COG1426@1|root,COG0484@2|Bacteria,COG1426@2|Bacteria,1Q8MB@1224|Proteobacteria,4330B@68525|delta/epsilon subdivisions,2WYCP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	DnaJ,HTH_25
k59_211245_2	1242864.D187_006684	7.89e-17	84.3	COG0455@1|root,COG0455@2|Bacteria,1R8IW@1224|Proteobacteria,42R3H@68525|delta/epsilon subdivisions,2WMNY@28221|Deltaproteobacteria,2YUZU@29|Myxococcales	28221|Deltaproteobacteria	D	NUBPL iron-transfer P-loop NTPase	-	-	-	ko:K04562	-	-	-	-	ko00000,ko02035	-	-	-	AAA_31,CbiA,HTH_25,ParA
k59_218815_1	1144275.COCOR_02487	1.25e-22	100.0	COG1651@1|root,COG1651@2|Bacteria,1MX2T@1224|Proteobacteria,42S4E@68525|delta/epsilon subdivisions,2WNJ8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Thioredoxin	-	-	-	-	-	-	-	-	-	-	-	-	SurA_N_3,Thioredoxin_4
k59_14905_1	671143.DAMO_2403	1.01e-47	160.0	COG0632@1|root,COG0632@2|Bacteria,2NPR6@2323|unclassified Bacteria	2|Bacteria	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB	ruvA	GO:0000217,GO:0000400,GO:0000724,GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003678,GO:0003824,GO:0004386,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009314,GO:0009378,GO:0009379,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0022607,GO:0031668,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0033554,GO:0034641,GO:0042802,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051276,GO:0051289,GO:0051716,GO:0065003,GO:0071103,GO:0071496,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1902494	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_C,RuvA_N
k59_131171_1	999541.bgla_1g37510	2.17e-63	204.0	COG0601@1|root,COG0601@2|Bacteria,1MU8Z@1224|Proteobacteria,2VHND@28216|Betaproteobacteria,1K2B3@119060|Burkholderiaceae	28216|Betaproteobacteria	P	PFAM binding-protein-dependent transport systems inner membrane component	dppB	-	-	ko:K12369	ko02010,map02010	M00324	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
k59_131171_2	207559.Dde_1183	3.56e-11	64.3	COG1173@1|root,COG1173@2|Bacteria,1MUG0@1224|Proteobacteria,43B4R@68525|delta/epsilon subdivisions,2X5VN@28221|Deltaproteobacteria,2MGWB@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02034,ko:K12370	ko02010,ko02024,map02010,map02024	M00239,M00324	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
k59_85499_1	706587.Desti_0208	2.9e-73	233.0	COG0477@1|root,COG2814@2|Bacteria,1MWFH@1224|Proteobacteria,42QX9@68525|delta/epsilon subdivisions,2WKS8@28221|Deltaproteobacteria,2MRU4@213462|Syntrophobacterales	28221|Deltaproteobacteria	EGP	Major Facilitator Superfamily	-	-	-	ko:K08224	-	-	-	-	ko00000,ko02000	2.A.1.36	-	-	MFS_1
k59_229586_1	1123033.ARNF01000071_gene141	1.31e-42	154.0	COG1638@1|root,COG1638@2|Bacteria,1MVHI@1224|Proteobacteria,1RPA8@1236|Gammaproteobacteria,3NRK9@468|Moraxellaceae	1236|Gammaproteobacteria	G	Bacterial extracellular solute-binding protein, family 7	-	-	-	-	-	-	-	-	-	-	-	-	DctP
k59_9837_1	1121405.dsmv_3002	2.74e-39	139.0	COG1737@1|root,COG1737@2|Bacteria,1PKMI@1224|Proteobacteria,42QMV@68525|delta/epsilon subdivisions,2WKNY@28221|Deltaproteobacteria,2MITX@213118|Desulfobacterales	28221|Deltaproteobacteria	K	Helix-turn-helix domain, rpiR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_6,SIS
k59_70348_2	1232437.KL661978_gene3778	2.43e-21	88.6	COG1371@1|root,COG1371@2|Bacteria,1NCP6@1224|Proteobacteria,42VQE@68525|delta/epsilon subdivisions,2WS6C@28221|Deltaproteobacteria,2MM59@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Archease protein family (MTH1598/TM1083)	-	-	-	-	-	-	-	-	-	-	-	-	Archease
k59_199295_1	933262.AXAM01000002_gene543	8.01e-83	258.0	COG1916@1|root,COG1916@2|Bacteria,1MWJ0@1224|Proteobacteria,42P2H@68525|delta/epsilon subdivisions,2WJQM@28221|Deltaproteobacteria,2MI76@213118|Desulfobacterales	28221|Deltaproteobacteria	S	TIGRFAM TraB family protein	-	-	-	-	-	-	-	-	-	-	-	-	TraB
k59_191664_2	880073.Calab_3054	1.13e-22	90.9	COG1839@1|root,COG1839@2|Bacteria,2NPAQ@2323|unclassified Bacteria	2|Bacteria	S	Adenosine specific kinase	-	-	-	ko:K09129	-	-	-	-	ko00000	-	-	-	Adenosine_kin
k59_154032_1	33876.JNXY01000006_gene1340	1.19e-83	257.0	COG0524@1|root,COG0524@2|Bacteria,2HU2B@201174|Actinobacteria,4DAJP@85008|Micromonosporales	201174|Actinobacteria	G	pfkB family carbohydrate kinase	-	-	2.7.1.45	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00061,M00308,M00631	R01541	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PfkB
k59_24865_1	1370125.AUWT01000011_gene1716	2.4e-06	48.9	COG2261@1|root,COG2261@2|Bacteria,2GSMN@201174|Actinobacteria,239ZC@1762|Mycobacteriaceae	201174|Actinobacteria	S	Transglycosylase associated protein	-	-	-	-	-	-	-	-	-	-	-	-	Transgly_assoc
k59_24865_4	1121403.AUCV01000056_gene3022	4.04e-68	218.0	COG0330@1|root,COG0330@2|Bacteria,1MV7R@1224|Proteobacteria,42N2V@68525|delta/epsilon subdivisions,2WIPS@28221|Deltaproteobacteria,2MIPC@213118|Desulfobacterales	28221|Deltaproteobacteria	O	HflC and HflK could regulate a protease	hflC	-	-	ko:K04087	-	M00742	-	-	ko00000,ko00002,ko01000	-	-	-	Band_7
k59_55398_1	880072.Desac_2217	2.44e-27	108.0	COG2885@1|root,COG2885@2|Bacteria,1MZTV@1224|Proteobacteria,42R5H@68525|delta/epsilon subdivisions,2WNZS@28221|Deltaproteobacteria,2MQNZ@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	OmpA family	pal	-	-	ko:K03640	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	OmpA
k59_229597_1	589865.DaAHT2_1278	1.05e-43	150.0	COG0307@1|root,COG0307@2|Bacteria,1MUMB@1224|Proteobacteria,42QT1@68525|delta/epsilon subdivisions,2WNK6@28221|Deltaproteobacteria,2MJM4@213118|Desulfobacterales	28221|Deltaproteobacteria	H	TIGRFAM riboflavin synthase, alpha subunit	ribE	-	2.5.1.9	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00066	RC00958,RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	Lum_binding
k59_115676_1	483219.LILAB_36350	3.21e-07	52.0	COG4796@1|root,COG4796@2|Bacteria,1QTT6@1224|Proteobacteria,42MKN@68525|delta/epsilon subdivisions,2WJV6@28221|Deltaproteobacteria,2YTV4@29|Myxococcales	28221|Deltaproteobacteria	U	type IV pilus secretin PilQ	pilQ	-	-	ko:K02666	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	AMIN,STN,Secretin,Secretin_N
k59_115676_2	439235.Dalk_4816	3.19e-68	223.0	COG3267@1|root,COG3267@2|Bacteria,1MU3G@1224|Proteobacteria,42QBH@68525|delta/epsilon subdivisions,2WISQ@28221|Deltaproteobacteria,2MIRA@213118|Desulfobacterales	28221|Deltaproteobacteria	U	AAA domain	-	-	-	ko:K02450	-	M00331	-	-	ko00000,ko00002,ko02044	9.B.42	-	-	AAA_22,Phage_tail_X
k59_24891_1	196490.AUEZ01000038_gene5714	4.47e-47	162.0	COG0411@1|root,COG0411@2|Bacteria,1MUFT@1224|Proteobacteria,2U22X@28211|Alphaproteobacteria,3JRTA@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	Branched-chain amino acid ATP-binding cassette transporter	MA20_16465	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
k59_32455_1	1121405.dsmv_2971	6.36e-43	154.0	COG5598@1|root,COG5598@2|Bacteria,1MWJN@1224|Proteobacteria,42N1X@68525|delta/epsilon subdivisions,2WKMS@28221|Deltaproteobacteria,2MIZN@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Trimethylamine methyltransferase MttB (TMA methyltransferase)	-	-	2.1.1.250	ko:K14083	ko00680,ko01120,ko01200,map00680,map01120,map01200	M00563	R09124,R10016	RC00035,RC00732,RC01144,RC02984	ko00000,ko00001,ko00002,ko01000	-	-	-	MTTB
k59_70363_1	404380.Gbem_3813	2.43e-52	177.0	COG2038@1|root,COG2038@2|Bacteria,1MVAM@1224|Proteobacteria,42M3Z@68525|delta/epsilon subdivisions,2WJIR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB)	cobT	GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008939,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0017144,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042364,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.4.2.21	ko:K00768	ko00860,ko01100,map00860,map01100	M00122	R04148	RC00033,RC00063	ko00000,ko00001,ko00002,ko01000	-	-	-	DBI_PRT
k59_138821_1	886293.Sinac_4767	1.25e-10	67.4	COG3464@1|root,COG3464@2|Bacteria,2IZV3@203682|Planctomycetes	203682|Planctomycetes	L	PFAM Uncharacterised protein family (UPF0236)	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_214371_1	466038.KI421440_gene1452	1.5e-112	329.0	COG0395@1|root,COG0395@2|Bacteria,1MXEM@1224|Proteobacteria,2TUQV@28211|Alphaproteobacteria,4BS0Y@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	G	PFAM Binding-protein-dependent transport system inner membrane component	ycjP	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
k59_214371_2	466038.KI421440_gene1453	1.76e-57	189.0	COG3842@1|root,COG3842@2|Bacteria,1QU06@1224|Proteobacteria,2TWIE@28211|Alphaproteobacteria,4BTES@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K17324	ko02010,map02010	M00607	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.35	-	-	ABC_tran,TOBE_2
k59_168791_1	317619.ANKN01000053_gene1977	1.68e-18	83.6	COG0842@1|root,COG0842@2|Bacteria,1G01R@1117|Cyanobacteria	1117|Cyanobacteria	V	TIGRFAM ABC-2 type transporter, NodJ family	-	-	-	ko:K09694	ko02010,map02010	M00252	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.102	-	-	ABC2_membrane
k59_168791_2	56780.SYN_00774	4.47e-123	360.0	COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,42MV1@68525|delta/epsilon subdivisions,2WM7T@28221|Deltaproteobacteria,2MQFC@213462|Syntrophobacterales	28221|Deltaproteobacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990,ko:K09695	ko02010,map02010	M00252,M00254	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.102	-	-	ABC_tran,DUF4162
k59_222177_1	335543.Sfum_1368	2.98e-19	84.7	COG1399@1|root,COG1399@2|Bacteria,1N7GQ@1224|Proteobacteria,42U2P@68525|delta/epsilon subdivisions,2WRMV@28221|Deltaproteobacteria,2MS4U@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Uncharacterized ACR, COG1399	-	-	-	ko:K07040	-	-	-	-	ko00000	-	-	-	DUF177
k59_168792_1	7668.SPU_025385-tr	4.97e-66	230.0	COG2801@1|root,KOG0017@2759|Eukaryota,38F42@33154|Opisthokonta,3BA5H@33208|Metazoa	33208|Metazoa	OU	K02A2.6-like	-	-	-	-	-	-	-	-	-	-	-	-	RVT_1,SCAN,gag-asp_proteas,rve,zf-CCHC,zf-H2C2
k59_154048_1	933262.AXAM01000002_gene567	8.54e-66	223.0	COG0045@1|root,COG1042@1|root,COG1670@1|root,COG0045@2|Bacteria,COG1042@2|Bacteria,COG1670@2|Bacteria,1MW98@1224|Proteobacteria,42KZW@68525|delta/epsilon subdivisions,2WIQB@28221|Deltaproteobacteria,2MIWX@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM CoA-binding domain protein	acs	-	-	ko:K09181	-	-	-	-	ko00000	-	-	-	ATP-grasp_5,Acetyltransf_1,Acetyltransf_3,CoA_binding_2,Succ_CoA_lig
k59_47747_1	1265505.ATUG01000002_gene1548	3.55e-93	286.0	COG1012@1|root,COG1012@2|Bacteria,1MUHV@1224|Proteobacteria,42MVJ@68525|delta/epsilon subdivisions,2WKM4@28221|Deltaproteobacteria,2MPW1@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Aldehyde dehydrogenase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldedh
k59_24898_1	1121929.KB898662_gene611	3.03e-14	72.4	COG1218@1|root,COG1218@2|Bacteria,1UYA1@1239|Firmicutes,4HDME@91061|Bacilli,470G1@74385|Gracilibacillus	91061|Bacilli	P	Inositol monophosphatase family	-	-	3.1.3.7	ko:K01082	ko00920,ko01100,ko01120,ko01130,map00920,map01100,map01120,map01130	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03016	-	-	-	Inositol_P
k59_2130_1	439235.Dalk_3782	1.49e-203	580.0	COG0511@1|root,COG5016@1|root,COG0511@2|Bacteria,COG5016@2|Bacteria,1QTTG@1224|Proteobacteria,43BUE@68525|delta/epsilon subdivisions,2X75I@28221|Deltaproteobacteria,2MPKE@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Conserved carboxylase domain	oadA	-	2.1.3.1,4.1.1.3,6.4.1.1	ko:K01571,ko:K01960,ko:K03416	ko00020,ko00620,ko00640,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00640,map00720,map01100,map01120,map01200,map01230	M00173,M00620	R00217,R00344,R00353,R00930	RC00040,RC00097,RC00367	ko00000,ko00001,ko00002,ko01000,ko02000	3.B.1.1.1	-	-	Biotin_lipoyl,HMGL-like,PYC_OADA
k59_47750_1	1124780.ANNU01000044_gene475	6.79e-31	115.0	COG4974@1|root,COG4974@2|Bacteria,4NGB5@976|Bacteroidetes,47PJP@768503|Cytophagia	976|Bacteroidetes	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
k59_47750_2	768706.Desor_1960	9.1e-22	95.1	COG0517@1|root,COG0517@2|Bacteria,1TQ4J@1239|Firmicutes,24B68@186801|Clostridia,260BK@186807|Peptococcaceae	186801|Clostridia	S	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	Y2_Tnp,Zn_Tnp_IS91
k59_9916_1	933262.AXAM01000106_gene2631	7.81e-25	102.0	COG2995@1|root,COG2995@2|Bacteria,1MWG1@1224|Proteobacteria,42R11@68525|delta/epsilon subdivisions,2WMWN@28221|Deltaproteobacteria,2MMZB@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Paraquat-inducible protein A	-	-	-	ko:K03808	-	-	-	-	ko00000	-	-	-	PqiA
k59_184114_1	767817.Desgi_0713	4.4e-162	484.0	COG0458@1|root,COG0458@2|Bacteria,1TPID@1239|Firmicutes,24819@186801|Clostridia,260WM@186807|Peptococcaceae	186801|Clostridia	EF	Belongs to the CarB family	carB2	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
k59_154068_1	1123270.ATUR01000002_gene2060	9.05e-31	121.0	COG1352@1|root,COG1352@2|Bacteria,1MU6W@1224|Proteobacteria,2TRQ3@28211|Alphaproteobacteria,2K0HS@204457|Sphingomonadales	204457|Sphingomonadales	NT	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP	-	-	2.1.1.80	ko:K00575	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheR,CheR_N
k59_47752_1	386456.JQKN01000012_gene986	3.11e-36	135.0	COG1736@1|root,arCOG04112@2157|Archaea,2XSY5@28890|Euryarchaeota,23NUP@183925|Methanobacteria	183925|Methanobacteria	J	Diphthamide	-	-	2.5.1.108	ko:K07561	-	-	R10455	RC00021,RC03180	ko00000,ko01000,ko03012	-	-	-	Diphthamide_syn
k59_123587_1	1499967.BAYZ01000152_gene1432	5.09e-58	188.0	COG1131@1|root,COG1131@2|Bacteria,2NPDQ@2323|unclassified Bacteria	2|Bacteria	V	ATPases associated with a variety of cellular activities	natA2	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
k59_32487_1	335543.Sfum_0862	4.53e-79	249.0	COG0683@1|root,COG0683@2|Bacteria,1MWJ1@1224|Proteobacteria,42MSJ@68525|delta/epsilon subdivisions,2WKHJ@28221|Deltaproteobacteria,2MQYJ@213462|Syntrophobacterales	28221|Deltaproteobacteria	E	Receptor family ligand binding region	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
k59_237279_1	429009.Adeg_1691	1.38e-34	124.0	COG4739@1|root,COG4739@2|Bacteria,1V3K5@1239|Firmicutes,24INA@186801|Clostridia,42FIV@68295|Thermoanaerobacterales	186801|Clostridia	S	Uncharacterized protein containing a ferredoxin domain (DUF2148)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2148
k59_184124_1	1444711.CCJF01000005_gene1716	7.18e-44	165.0	COG1916@1|root,COG1916@2|Bacteria,2JFDK@204428|Chlamydiae	204428|Chlamydiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_214973_2	1499967.BAYZ01000074_gene2123	4.24e-161	467.0	COG0438@1|root,COG0438@2|Bacteria,2NQHY@2323|unclassified Bacteria	2|Bacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1,Glycos_transf_2
k59_207777_1	1048834.TC41_0607	1.08e-45	163.0	COG0128@1|root,COG0128@2|Bacteria,1TPIH@1239|Firmicutes,4HBHZ@91061|Bacilli	91061|Bacilli	E	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	aroA	-	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	EPSP_synthase
k59_146796_1	933262.AXAM01000038_gene900	6.97e-15	70.5	COG0103@1|root,COG0103@2|Bacteria,1RD4A@1224|Proteobacteria,42SVI@68525|delta/epsilon subdivisions,2WP7T@28221|Deltaproteobacteria,2MJVD@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Belongs to the universal ribosomal protein uS9 family	rpsI	-	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
k59_146796_2	96561.Dole_0946	2.35e-50	162.0	COG0102@1|root,COG0102@2|Bacteria,1RA11@1224|Proteobacteria,42SD5@68525|delta/epsilon subdivisions,2WP5M@28221|Deltaproteobacteria,2MKE6@213118|Desulfobacterales	28221|Deltaproteobacteria	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rplM	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
k59_40766_1	338963.Pcar_1009	5.1e-94	285.0	COG0668@1|root,COG0668@2|Bacteria,1MW7V@1224|Proteobacteria,42R90@68525|delta/epsilon subdivisions,2WMUJ@28221|Deltaproteobacteria,43SZC@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Mechanosensitive ion channel	mscS-2	-	-	-	-	-	-	-	-	-	-	-	MS_channel
k59_154687_2	247490.KSU1_D0030	4.73e-29	112.0	COG3945@1|root,COG3945@2|Bacteria,2J2KE@203682|Planctomycetes	203682|Planctomycetes	S	Hemerythrin HHE cation binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin
k59_169539_1	838561.P344_05935	6.74e-22	91.7	COG0164@1|root,COG0164@2|Bacteria,3WTNN@544448|Tenericutes	544448|Tenericutes	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhB	-	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
k59_169539_2	1499967.BAYZ01000027_gene1801	1.66e-20	88.2	COG0792@1|root,COG0792@2|Bacteria,2NPW8@2323|unclassified Bacteria	2|Bacteria	L	Nuclease-related domain	yraN	-	-	ko:K07460	-	-	-	-	ko00000	-	-	-	UPF0102
k59_2657_1	644282.Deba_2892	5.76e-37	142.0	COG0457@1|root,COG0501@1|root,COG0457@2|Bacteria,COG0501@2|Bacteria,1R5A7@1224|Proteobacteria,42MP6@68525|delta/epsilon subdivisions,2WK92@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	peptidase M48, Ste24p	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48,TPR_11,TPR_17
k59_192274_1	1120985.AUMI01000017_gene2712	2e-64	218.0	COG0446@1|root,COG0446@2|Bacteria,1TPWW@1239|Firmicutes,4H26Y@909932|Negativicutes	909932|Negativicutes	P	pyridine nucleotide-disulfide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Pyr_redox_dim,Rhodanese
k59_17887_1	1279015.KB908455_gene1293	1.38e-12	73.2	COG4974@1|root,COG4974@2|Bacteria,1MVAN@1224|Proteobacteria,1RMSS@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
k59_131808_1	573370.DMR_01320	6.82e-60	193.0	COG2207@1|root,COG2207@2|Bacteria,1MUEM@1224|Proteobacteria,42S1Y@68525|delta/epsilon subdivisions,2WP4J@28221|Deltaproteobacteria,2M9EU@213115|Desulfovibrionales	28221|Deltaproteobacteria	K	PFAM AraC-type transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	AraC_N,HTH_18
k59_192279_1	644282.Deba_1483	1.04e-12	67.8	29HYV@1|root,304VW@2|Bacteria,1RDPY@1224|Proteobacteria,42RXW@68525|delta/epsilon subdivisions,2WNTT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_192279_2	1232410.KI421416_gene2675	4.07e-28	104.0	COG0599@1|root,COG0599@2|Bacteria,1N2ZQ@1224|Proteobacteria,42VDR@68525|delta/epsilon subdivisions,2WRKS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM Carboxymuconolactone decarboxylase	-	-	-	-	-	-	-	-	-	-	-	-	CMD
k59_86051_1	335543.Sfum_0677	1.02e-65	217.0	COG5016@1|root,COG5016@2|Bacteria	2|Bacteria	C	pyruvate	-	-	4.1.1.3,6.4.1.1	ko:K01571,ko:K01958,ko:K01960	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	M00173,M00620	R00217,R00344	RC00040,RC00367	ko00000,ko00001,ko00002,ko01000,ko02000	3.B.1.1.1	-	-	Biotin_lipoyl,HMGL-like,PYC_OADA
k59_78830_2	626887.J057_23810	5.62e-68	211.0	2DC7W@1|root,2ZD7C@2|Bacteria,1QU8S@1224|Proteobacteria,1S6MA@1236|Gammaproteobacteria,46BPC@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Chalcone isomerase-like	-	-	-	-	-	-	-	-	-	-	-	-	Chalcone_3
k59_124460_1	457429.ABJI02000040_gene3857	3.54e-61	198.0	COG0426@1|root,COG0426@2|Bacteria,2GJT6@201174|Actinobacteria	201174|Actinobacteria	C	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Flavodoxin_1,Lactamase_B
k59_10482_1	640511.BC1002_1318	7.09e-24	102.0	COG1309@1|root,COG1309@2|Bacteria,1RC1X@1224|Proteobacteria,2VYH2@28216|Betaproteobacteria,1K12H@119060|Burkholderiaceae	28216|Betaproteobacteria	K	WHG domain	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N,WHG
k59_89572_1	365044.Pnap_1343	1.07e-32	130.0	COG0644@1|root,COG0644@2|Bacteria,1MZVI@1224|Proteobacteria,2VH6J@28216|Betaproteobacteria,4ABDG@80864|Comamonadaceae	28216|Betaproteobacteria	C	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Trp_halogenase
k59_180028_1	335543.Sfum_2792	8.01e-35	123.0	COG1014@1|root,COG1014@2|Bacteria,1N12F@1224|Proteobacteria,42NN1@68525|delta/epsilon subdivisions,2WQFN@28221|Deltaproteobacteria,2MQDU@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	PFAM pyruvate ferredoxin flavodoxin oxidoreductase	-	-	1.2.7.1	ko:K00172	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,POR
k59_135395_2	1320556.AVBP01000010_gene3288	7.31e-10	61.6	COG0683@1|root,COG0683@2|Bacteria,1NHBN@1224|Proteobacteria,2TWTC@28211|Alphaproteobacteria,43GWM@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	E	COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
k59_66408_1	1122919.KB905587_gene3858	4.37e-30	122.0	COG0587@1|root,COG0587@2|Bacteria,1TPYG@1239|Firmicutes,4H9T3@91061|Bacilli,26QTS@186822|Paenibacillaceae	91061|Bacilli	L	DNA polymerase	dnaE	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
k59_225772_1	1227454.C446_15528	2.64e-27	102.0	COG1254@1|root,arCOG01674@2157|Archaea,2XYT5@28890|Euryarchaeota,23WSX@183963|Halobacteria	183963|Halobacteria	C	Belongs to the acylphosphatase family	acyP	-	3.6.1.7	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	-	R00317,R01421,R01515	RC00043	ko00000,ko00001,ko01000	-	-	-	Acylphosphatase
k59_97098_1	398767.Glov_1520	1.03e-46	165.0	COG2519@1|root,COG3119@1|root,COG2519@2|Bacteria,COG3119@2|Bacteria,1NIZU@1224|Proteobacteria,42Z5U@68525|delta/epsilon subdivisions,2WU2U@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
k59_203390_1	246200.SPO3036	3.68e-232	656.0	COG2015@1|root,COG2015@2|Bacteria,1MU82@1224|Proteobacteria,2TSM1@28211|Alphaproteobacteria,4ND2Q@97050|Ruegeria	28211|Alphaproteobacteria	Q	Alkyl sulfatase dimerisation	-	-	-	-	-	-	-	-	-	-	-	-	Alkyl_sulf_C,Alkyl_sulf_dimr,Lactamase_B
k59_188522_1	345073.VC395_A0503	1.37e-44	150.0	COG1943@1|root,COG1943@2|Bacteria,1RAP9@1224|Proteobacteria,1S230@1236|Gammaproteobacteria,1Y31N@135623|Vibrionales	135623|Vibrionales	L	to PID 1054866 PID 2271024	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
k59_135405_1	1298867.AUES01000051_gene4511	2.03e-16	85.1	COG0771@1|root,COG2931@1|root,COG4625@1|root,COG0771@2|Bacteria,COG2931@2|Bacteria,COG4625@2|Bacteria,1MU7T@1224|Proteobacteria,2TRVY@28211|Alphaproteobacteria,3K2H3@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	Q	Haemolysin-type calcium-binding repeat (2 copies)	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP,HemolysinCabind
k59_135406_1	1232437.KL662050_gene5290	5.9e-56	191.0	COG2204@1|root,COG5000@1|root,COG2204@2|Bacteria,COG5000@2|Bacteria,1RBB9@1224|Proteobacteria,42R73@68525|delta/epsilon subdivisions,2WMPX@28221|Deltaproteobacteria,2MMXA@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Histidine kinase-like ATPases	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,Response_reg
k59_172900_1	177437.HRM2_09950	1.45e-44	159.0	COG0365@1|root,COG0365@2|Bacteria,1MUX7@1224|Proteobacteria,42P5R@68525|delta/epsilon subdivisions,2WJDU@28221|Deltaproteobacteria,2MI4P@213118|Desulfobacterales	28221|Deltaproteobacteria	I	PFAM AMP-dependent synthetase and ligase	-	-	6.2.1.16	ko:K01907	ko00280,ko00650,map00280,map00650	-	R01357	RC00004,RC00014	ko00000,ko00001,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
k59_14269_1	555779.Dthio_PD2605	1.02e-32	129.0	COG3039@1|root,COG3039@2|Bacteria,1QQ9Q@1224|Proteobacteria,42S7X@68525|delta/epsilon subdivisions,2WNJ2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	PFAM transposase, IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DUF772
k59_240911_1	1121448.DGI_2712	5.62e-15	81.3	COG0642@1|root,COG1352@1|root,COG2201@1|root,COG0642@2|Bacteria,COG1352@2|Bacteria,COG2201@2|Bacteria,1NXDJ@1224|Proteobacteria,43BMJ@68525|delta/epsilon subdivisions,2WUEV@28221|Deltaproteobacteria,2MH9E@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	response regulator, receiver	-	-	2.1.1.80,3.1.1.61	ko:K13924	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,CheR,CheR_N,HATPase_c,HisKA,PAS_4,Response_reg
k59_89592_1	1499967.BAYZ01000101_gene3596	1.95e-31	121.0	COG2204@1|root,COG2204@2|Bacteria,2NQQY@2323|unclassified Bacteria	2|Bacteria	T	Sigma-54 interaction domain	-	-	-	ko:K07713	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	FHA,GAF_3,HTH_8,Response_reg,Sigma54_activat
k59_164928_1	1408422.JHYF01000002_gene2282	7.8e-36	139.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247Q0@186801|Clostridia,36DEY@31979|Clostridiaceae	186801|Clostridia	V	ABC transporter transmembrane region	-	-	-	ko:K18889	ko02010,map02010	M00707	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.106.13,3.A.1.106.5	-	-	ABC_membrane,ABC_tran
k59_5190_1	177437.HRM2_28330	3.19e-99	310.0	COG0247@1|root,COG1139@1|root,COG0247@2|Bacteria,COG1139@2|Bacteria,1MV6J@1224|Proteobacteria,42MN2@68525|delta/epsilon subdivisions,2WIMJ@28221|Deltaproteobacteria,2MHXI@213118|Desulfobacterales	28221|Deltaproteobacteria	C	LUD domain	-	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_7,Fer4_8,LUD_dom
k59_142921_1	981327.F925_03078	1.54e-34	129.0	COG2059@1|root,COG2059@2|Bacteria,1MUBW@1224|Proteobacteria,1RPNP@1236|Gammaproteobacteria,3NIMY@468|Moraxellaceae	1236|Gammaproteobacteria	P	Chromate transporter	chrA	-	-	ko:K07240	-	-	-	-	ko00000,ko02000	2.A.51.1	-	-	Chromate_transp
k59_142925_1	933262.AXAM01000010_gene1372	1.69e-74	230.0	COG0084@1|root,COG0084@2|Bacteria,1MUC0@1224|Proteobacteria,42MMS@68525|delta/epsilon subdivisions,2WMUI@28221|Deltaproteobacteria,2MIBY@213118|Desulfobacterales	28221|Deltaproteobacteria	L	TIGRFAM hydrolase, TatD family	tatD	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	Fer4_14,Radical_SAM,TatD_DNase
k59_240916_1	1191523.MROS_0609	3.7e-85	261.0	COG0407@1|root,COG0407@2|Bacteria	2|Bacteria	H	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III	hemE	GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006536,GO:0006725,GO:0006778,GO:0006779,GO:0006780,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009064,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019353,GO:0019438,GO:0019752,GO:0033013,GO:0033014,GO:0033526,GO:0034641,GO:0042168,GO:0042440,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046394,GO:0046483,GO:0046501,GO:0046502,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	iPC815.YPO3734,iSBO_1134.SBO_4018	URO-D
k59_195133_1	335543.Sfum_0064	2.83e-78	241.0	COG0548@1|root,COG0548@2|Bacteria,1MU17@1224|Proteobacteria,42N8G@68525|delta/epsilon subdivisions,2WKBC@28221|Deltaproteobacteria,2MQ75@213462|Syntrophobacterales	28221|Deltaproteobacteria	F	Belongs to the acetylglutamate kinase family. ArgB subfamily	argB	GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.2.8	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R02649	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
k59_5202_1	1121405.dsmv_3130	7.36e-155	442.0	COG0192@1|root,COG0192@2|Bacteria,1MUFQ@1224|Proteobacteria,42MFM@68525|delta/epsilon subdivisions,2WIQ3@28221|Deltaproteobacteria,2MHVQ@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
k59_20996_1	675817.VDA_002416	4.36e-86	265.0	COG4974@1|root,COG4974@2|Bacteria,1MVAN@1224|Proteobacteria,1S1WF@1236|Gammaproteobacteria,1Y2TW@135623|Vibrionales	135623|Vibrionales	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
k59_180057_1	246969.TAM4_1154	3.41e-57	191.0	COG1474@1|root,arCOG00467@2157|Archaea,2XU73@28890|Euryarchaeota,242PQ@183968|Thermococci	183968|Thermococci	L	Involved in regulation of DNA replication	cdc6	-	-	ko:K10725	-	-	-	-	ko00000,ko03032	-	-	-	AAA,AAA_16,Cdc6_C
k59_234092_1	1121396.KB893054_gene2411	2.4e-24	104.0	COG1284@1|root,COG1284@2|Bacteria,1R3UZ@1224|Proteobacteria,42P9H@68525|delta/epsilon subdivisions,2WIUG@28221|Deltaproteobacteria,2MJ34@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Uncharacterised 5xTM membrane BCR, YitT family COG1284	-	-	-	-	-	-	-	-	-	-	-	-	DUF2179,YitT_membrane
k59_149661_1	56780.SYN_01430	1.36e-45	159.0	COG2197@1|root,COG4191@1|root,COG2197@2|Bacteria,COG4191@2|Bacteria,1R7ED@1224|Proteobacteria,42PQ7@68525|delta/epsilon subdivisions,2WMHZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,PAS_8
k59_97121_1	706587.Desti_2612	7.24e-98	302.0	COG1053@1|root,COG1053@2|Bacteria,1MU5M@1224|Proteobacteria,42M81@68525|delta/epsilon subdivisions,2WJXY@28221|Deltaproteobacteria,2MRE3@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	succinate dehydrogenase or fumarate reductase, flavoprotein	-	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
k59_203410_1	667014.Thein_1162	2.76e-46	164.0	COG2204@1|root,COG2204@2|Bacteria,2GH1I@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	T	Bacterial regulatory protein, Fis family	-	-	-	ko:K13599	ko02020,map02020	M00498	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
k59_203410_2	227086.JGI_V11_145769	2.02e-10	63.9	COG0742@1|root,2QSWU@2759|Eukaryota	2759|Eukaryota	L	Conserved hypothetical protein 95	-	-	-	-	-	-	-	-	-	-	-	-	Cons_hypoth95
k59_157894_1	1049564.TevJSym_ab00470	3.48e-47	171.0	2A6A4@1|root,30V2R@2|Bacteria,1RENE@1224|Proteobacteria,1SNHE@1236|Gammaproteobacteria,1JA5P@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_74400_5	547042.BACCOPRO_02130	2.17e-21	91.7	28K97@1|root,2Z9WV@2|Bacteria,4P1GF@976|Bacteroidetes,2FS5S@200643|Bacteroidia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_189150_1	986075.CathTA2_1988	7.42e-06	51.2	COG0517@1|root,COG0517@2|Bacteria,1V0XU@1239|Firmicutes,4HD12@91061|Bacilli	91061|Bacilli	S	acetoin utilization protein	acuB	-	-	ko:K04767	-	-	-	-	ko00000	-	-	-	ACT,CBS
k59_128136_1	90813.JQMT01000001_gene1666	1.72e-85	268.0	COG2207@1|root,COG2207@2|Bacteria,1MX23@1224|Proteobacteria,1RN7K@1236|Gammaproteobacteria,461CP@72273|Thiotrichales	72273|Thiotrichales	K	Arabinose-binding domain of AraC transcription regulator, N-term	-	-	-	-	-	-	-	-	-	-	-	-	Arabinose_bd,HTH_18
k59_37249_1	1459636.NTE_00443	4.25e-24	106.0	COG0308@1|root,arCOG02969@2157|Archaea,41SJH@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Peptidase family M1 domain	-	-	3.4.11.2	ko:K01256,ko:K13722	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	ERAP1_C,Peptidase_M1
k59_143626_1	395493.BegalDRAFT_2198	1.22e-75	238.0	COG2984@1|root,COG2984@2|Bacteria,1R84M@1224|Proteobacteria,1SYRV@1236|Gammaproteobacteria,462DD@72273|Thiotrichales	72273|Thiotrichales	S	ABC transporter substrate binding protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC_sub_bind
k59_14820_1	667014.Thein_1409	8.58e-64	220.0	COG0574@1|root,COG3848@1|root,COG0574@2|Bacteria,COG3848@2|Bacteria,2GGWR@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	GT	Pyruvate phosphate dikinase, PEP/pyruvate binding domain	-	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PPDK_N
k59_241394_1	498761.HM1_2802	8.29e-64	212.0	COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,1TQ38@1239|Firmicutes,2484Z@186801|Clostridia	186801|Clostridia	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses	nadE	-	6.3.5.1	ko:K01950	ko00760,ko01100,map00760,map01100	M00115	R00257	RC00010,RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase,NAD_synthase
k59_67002_1	1094715.CM001373_gene2496	2.86e-64	207.0	COG0708@1|root,COG0708@2|Bacteria,1MVII@1224|Proteobacteria,1RN4H@1236|Gammaproteobacteria,1JCXN@118969|Legionellales	118969|Legionellales	L	Endonuclease/Exonuclease/phosphatase family	xthA	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
k59_143628_1	1502851.FG93_00239	9.23e-49	167.0	COG0697@1|root,COG0697@2|Bacteria,1MZQM@1224|Proteobacteria,2TUPG@28211|Alphaproteobacteria,3JS7M@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
k59_74878_1	1121405.dsmv_0189	7.24e-92	291.0	COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,42MI5@68525|delta/epsilon subdivisions,2WITQ@28221|Deltaproteobacteria,2MI9V@213118|Desulfobacterales	28221|Deltaproteobacteria	I	3-hydroxyacyl-CoA dehydrogenase	-	-	1.1.1.35	ko:K07516	ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212	M00087	R01975,R04737,R04739,R04741,R04743,R04745,R04748,R05305	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000	-	-	-	3HCDH,3HCDH_N,ECH_1,ECH_2
k59_241400_1	338966.Ppro_0674	1.38e-81	271.0	COG0086@1|root,COG0086@2|Bacteria,1MU3M@1224|Proteobacteria,42NAW@68525|delta/epsilon subdivisions,2WISU@28221|Deltaproteobacteria,43UIG@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	-	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
k59_67007_1	1232437.KL661978_gene3869	2.8e-29	117.0	COG1413@1|root,COG3634@1|root,COG1413@2|Bacteria,COG3634@2|Bacteria,1Q3CD@1224|Proteobacteria,42NRD@68525|delta/epsilon subdivisions,2WIKD@28221|Deltaproteobacteria,2MJ9V@213118|Desulfobacterales	28221|Deltaproteobacteria	O	lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_3
k59_234638_1	767817.Desgi_2290	6.58e-52	180.0	COG0591@1|root,COG0591@2|Bacteria,1TPVE@1239|Firmicutes,248NQ@186801|Clostridia	186801|Clostridia	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
k59_158457_2	1121439.dsat_1664	5.46e-07	53.9	COG2089@1|root,COG2089@2|Bacteria,1MWG3@1224|Proteobacteria,42ME3@68525|delta/epsilon subdivisions,2X5G5@28221|Deltaproteobacteria,2MGQH@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	NeuB family	-	-	2.5.1.56	ko:K01654	ko00520,ko01100,map00520,map01100	-	R01804,R04435	RC00159	ko00000,ko00001,ko01000	-	-	-	NeuB
k59_158461_1	335543.Sfum_1797	3.57e-80	247.0	COG1143@1|root,COG1143@2|Bacteria,1R412@1224|Proteobacteria,42ND5@68525|delta/epsilon subdivisions,2WIR2@28221|Deltaproteobacteria,2MQSB@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_82791_2	1121396.KB893060_gene2866	4.43e-28	107.0	COG1309@1|root,COG1309@2|Bacteria,1N7QG@1224|Proteobacteria,4347H@68525|delta/epsilon subdivisions,2X61R@28221|Deltaproteobacteria,2MP1S@213118|Desulfobacterales	28221|Deltaproteobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	ko:K09017	-	-	-	-	ko00000,ko03000	-	-	-	TetR_N
k59_136065_1	1265505.ATUG01000001_gene4448	1.39e-64	214.0	COG3666@1|root,COG3666@2|Bacteria,1N3QR@1224|Proteobacteria,42N7X@68525|delta/epsilon subdivisions,2WMM9@28221|Deltaproteobacteria,2MMU3@213118|Desulfobacterales	28221|Deltaproteobacteria	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_6,DUF772
k59_113041_2	335543.Sfum_3617	8.06e-48	161.0	COG1842@1|root,COG1842@2|Bacteria,1Q6II@1224|Proteobacteria,43383@68525|delta/epsilon subdivisions,2WY57@28221|Deltaproteobacteria	28221|Deltaproteobacteria	KT	PFAM PspA IM30 family	-	-	-	ko:K03969	-	-	-	-	ko00000	-	-	-	PspA_IM30
k59_113041_3	1499967.BAYZ01000111_gene2948	4.31e-60	202.0	COG2304@1|root,COG2304@2|Bacteria	2|Bacteria	IU	oxidoreductase activity	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA
k59_180684_1	96561.Dole_0333	3.39e-64	207.0	COG4972@1|root,COG4972@2|Bacteria,1MX8P@1224|Proteobacteria,42M36@68525|delta/epsilon subdivisions,2WJFJ@28221|Deltaproteobacteria,2MID0@213118|Desulfobacterales	28221|Deltaproteobacteria	NU	TIGRFAM type IV pilus assembly protein PilM	pilM	-	-	ko:K02662	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilM_2
k59_211817_3	1220535.IMCC14465_07590	0.000503	50.1	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,2TRJF@28211|Alphaproteobacteria,4BPHH@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
k59_128173_1	335543.Sfum_1166	1.95e-66	213.0	COG0674@1|root,COG0674@2|Bacteria,1NBSJ@1224|Proteobacteria,42MS1@68525|delta/epsilon subdivisions,2WJ97@28221|Deltaproteobacteria,2MQWC@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	oxidoreductase, alpha subunit	korA	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR_N
k59_241438_1	248742.XP_005649299.1	7.79e-46	163.0	COG2515@1|root,2QPS1@2759|Eukaryota,37J4F@33090|Viridiplantae	33090|Viridiplantae	E	1-aminocyclopropane-1-carboxylate deaminase	D-CDES	GO:0000096,GO:0000098,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009063,GO:0009069,GO:0009071,GO:0009093,GO:0009507,GO:0009536,GO:0009692,GO:0009693,GO:0009987,GO:0010035,GO:0010038,GO:0010817,GO:0016054,GO:0016829,GO:0016846,GO:0019148,GO:0019447,GO:0019478,GO:0019752,GO:0042221,GO:0042445,GO:0042446,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043449,GO:0043450,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044273,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0046416,GO:0046438,GO:0046686,GO:0046872,GO:0046914,GO:0050896,GO:0050897,GO:0065007,GO:0065008,GO:0071704,GO:1900673,GO:1900674,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901605,GO:1901606	4.4.1.15	ko:K05396	ko00270,map00270	-	R01874	RC00382	ko00000,ko00001,ko01000	-	-	-	PALP
k59_105546_1	1120963.KB894497_gene2103	9.19e-06	50.8	COG3267@1|root,COG3267@2|Bacteria,1MU3G@1224|Proteobacteria,1RMI0@1236|Gammaproteobacteria,2PZW7@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	U	COG3267 Type II secretory pathway, component ExeA	gspA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K02450	-	M00331	-	-	ko00000,ko00002,ko02044	9.B.42	-	-	AAA_22,PG_binding_1,T2SSB
k59_14843_1	589865.DaAHT2_1474	3.56e-17	82.0	COG3852@1|root,COG3852@2|Bacteria,1MVN6@1224|Proteobacteria,43BPS@68525|delta/epsilon subdivisions,2X710@28221|Deltaproteobacteria,2MPN4@213118|Desulfobacterales	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
k59_14843_2	338966.Ppro_1849	1.25e-12	70.1	COG1729@1|root,COG1729@2|Bacteria,1NE9U@1224|Proteobacteria,42W04@68525|delta/epsilon subdivisions,2WSHK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16
k59_113064_2	926550.CLDAP_28530	3.53e-11	61.2	COG0589@1|root,COG0589@2|Bacteria,2G91P@200795|Chloroflexi	200795|Chloroflexi	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
k59_51890_2	671143.DAMO_1169	2.2e-25	102.0	2C8XG@1|root,2Z7PK@2|Bacteria,2NR2W@2323|unclassified Bacteria	2|Bacteria	S	Protein of unknown function (DUF4197)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4197
k59_37281_1	1279017.AQYJ01000026_gene58	3.61e-46	169.0	COG1361@1|root,COG4932@1|root,COG1361@2|Bacteria,COG4932@2|Bacteria,1R5G4@1224|Proteobacteria,1SEWA@1236|Gammaproteobacteria,469S7@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	Domain of unknown function DUF11	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,SdrD_B
k59_60112_1	1168034.FH5T_06360	3.08e-144	410.0	COG1484@1|root,COG1484@2|Bacteria,4NFE0@976|Bacteroidetes,2FPQ9@200643|Bacteroidia	976|Bacteroidetes	L	COG1484 DNA replication protein	-	-	-	-	-	-	-	-	-	-	-	-	IstB_IS21
k59_105553_2	1168065.DOK_17725	1.31e-15	76.6	COG1716@1|root,COG1716@2|Bacteria,1MW1M@1224|Proteobacteria,1S50X@1236|Gammaproteobacteria,1J761@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	T	Inner membrane component of T3SS, cytoplasmic domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA,Yop-YscD_cpl
k59_86444_1	323261.Noc_1745	4.79e-109	326.0	COG0535@1|root,COG0535@2|Bacteria,1MXM1@1224|Proteobacteria,1RNQ1@1236|Gammaproteobacteria,1X06Z@135613|Chromatiales	135613|Chromatiales	S	Radical SAM domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF3463,Radical_SAM
k59_169974_1	335543.Sfum_2445	6.98e-75	248.0	COG0751@1|root,COG0751@2|Bacteria,1MV2F@1224|Proteobacteria,42M6A@68525|delta/epsilon subdivisions,2WJIT@28221|Deltaproteobacteria,2MQBG@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	Glycyl-tRNA synthetase beta subunit	glyS	-	6.1.1.14	ko:K01879	ko00970,map00970	M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_1,tRNA_synt_2f
k59_238275_1	1121405.dsmv_3570	3.54e-62	203.0	COG0201@1|root,COG0201@2|Bacteria,1MVU7@1224|Proteobacteria,42MGM@68525|delta/epsilon subdivisions,2WIZ7@28221|Deltaproteobacteria,2MHM9@213118|Desulfobacterales	28221|Deltaproteobacteria	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	-	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
k59_238275_2	743719.PaelaDRAFT_5397	1.19e-23	94.7	COG0200@1|root,COG0200@2|Bacteria,1V3KE@1239|Firmicutes,4HFPW@91061|Bacilli,26WST@186822|Paenibacillaceae	91061|Bacilli	J	binds to the 23S rRNA	rplO	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02876	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27A
k59_124925_1	439235.Dalk_0825	3.94e-52	174.0	COG4974@1|root,COG4974@2|Bacteria,1MVNF@1224|Proteobacteria,42N0M@68525|delta/epsilon subdivisions,2WJ7D@28221|Deltaproteobacteria,2MHZH@213118|Desulfobacterales	28221|Deltaproteobacteria	L	TIGRFAM tyrosine recombinase XerD	xerD	-	-	ko:K03733,ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
k59_109220_1	335543.Sfum_0588	1.11e-147	429.0	COG2704@1|root,COG2704@2|Bacteria,1MVHH@1224|Proteobacteria,42MDH@68525|delta/epsilon subdivisions,2WU9Z@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane	-	-	-	ko:K07791	-	-	-	-	ko00000,ko02000	2.A.13.1	-	-	DcuA_DcuB
k59_169977_1	1499967.BAYZ01000009_gene5391	2.07e-168	495.0	COG2766@1|root,COG2766@2|Bacteria	2|Bacteria	T	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	AAA_PrkA,PrkA
k59_94808_1	933262.AXAM01000003_gene2865	3.45e-29	116.0	COG0795@1|root,COG0795@2|Bacteria,1MVW3@1224|Proteobacteria,42N5X@68525|delta/epsilon subdivisions,2WJ3H@28221|Deltaproteobacteria,2MI77@213118|Desulfobacterales	28221|Deltaproteobacteria	S	permease YjgP YjgQ family	lptG	-	-	ko:K11720	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
k59_170640_1	1167006.UWK_00556	3.58e-105	313.0	COG3005@1|root,COG3005@2|Bacteria	2|Bacteria	C	denitrification pathway	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_c3_2,Cytochrome_C554,Ni_hydr_CYTB,Paired_CXXCH_1
k59_223537_1	477184.KYC_02229	1.13e-87	272.0	COG2220@1|root,COG2220@2|Bacteria,1MV20@1224|Proteobacteria,2VKI0@28216|Betaproteobacteria,3T67Z@506|Alcaligenaceae	28216|Betaproteobacteria	S	Zn-dependent hydrolases of the beta-lactamase fold	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
k59_125374_1	1461580.CCAS010000009_gene1276	2.92e-15	80.1	COG1352@1|root,COG1352@2|Bacteria,1TPD8@1239|Firmicutes,4HAS1@91061|Bacilli,1ZCKU@1386|Bacillus	91061|Bacilli	NT	COG1352 Methylase of chemotaxis methyl-accepting proteins	-	-	2.1.1.80,3.1.1.61	ko:K00575,ko:K13924	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,CheR,CheR_N,HATPase_c,HisKA,PAS_10,PAS_3,PAS_9
k59_140464_1	1304885.AUEY01000048_gene621	8.18e-16	82.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42N03@68525|delta/epsilon subdivisions,2WIX4@28221|Deltaproteobacteria,2MINP@213118|Desulfobacterales	28221|Deltaproteobacteria	NT	PFAM chemotaxis sensory transducer	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HBM,MCPsignal,dCache_1
k59_140464_2	316067.Geob_3500	6.74e-22	95.5	COG0247@1|root,COG0247@2|Bacteria,1MWTK@1224|Proteobacteria,42PGQ@68525|delta/epsilon subdivisions,2WMJB@28221|Deltaproteobacteria,43TEY@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Cysteine-rich domain	glpC	-	1.1.5.3	ko:K00113	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	CCG,Fer4_17,Fer4_8
k59_147474_1	443143.GM18_3417	1.57e-39	134.0	COG0640@1|root,COG0640@2|Bacteria,1RHCK@1224|Proteobacteria,42UU2@68525|delta/epsilon subdivisions,2WQJD@28221|Deltaproteobacteria,43VQZ@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_20,HTH_5
k59_147474_2	1121403.AUCV01000032_gene2890	5.56e-18	82.0	COG0648@1|root,COG0648@2|Bacteria,1MX4Y@1224|Proteobacteria,42MYE@68525|delta/epsilon subdivisions,2WJC7@28221|Deltaproteobacteria,2MIWS@213118|Desulfobacterales	28221|Deltaproteobacteria	L	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin	nfo	GO:0003674,GO:0003824,GO:0003906,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008081,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360	3.1.21.2	ko:K01151	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AP_endonuc_2
k59_170645_1	933262.AXAM01000003_gene2792	4.97e-82	257.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,42NB6@68525|delta/epsilon subdivisions,2WIWE@28221|Deltaproteobacteria,2MHQQ@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Belongs to the peptidase S1C family	degP	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
k59_87000_2	243231.GSU2468	1.52e-21	88.2	2E8BS@1|root,332QF@2|Bacteria,1N9X2@1224|Proteobacteria,431DN@68525|delta/epsilon subdivisions,2WX5W@28221|Deltaproteobacteria,43VDY@69541|Desulfuromonadales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_57124_1	319795.Dgeo_1548	1.27e-15	79.0	COG0789@1|root,COG0789@2|Bacteria,1WJ4G@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	K	PFAM MerR family regulatory protein	-	-	-	ko:K13640	-	-	-	-	ko00000,ko03000	-	-	-	MerR_1
k59_208800_1	1121405.dsmv_2749	2.87e-122	376.0	COG0058@1|root,COG0058@2|Bacteria,1MW4J@1224|Proteobacteria,42MEQ@68525|delta/epsilon subdivisions,2WIPF@28221|Deltaproteobacteria,2MIPG@213118|Desulfobacterales	28221|Deltaproteobacteria	G	phosphorylase	glgP	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	DUF3417,Phosphorylase
k59_170652_1	933262.AXAM01000041_gene1904	2.58e-99	296.0	COG0685@1|root,COG0685@2|Bacteria,1MXTZ@1224|Proteobacteria,42NTS@68525|delta/epsilon subdivisions,2WK04@28221|Deltaproteobacteria,2MIIA@213118|Desulfobacterales	28221|Deltaproteobacteria	E	PFAM Methylenetetrahydrofolate reductase	-	-	1.5.1.20,2.1.1.10	ko:K00297,ko:K00547	ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523	M00377	R00650,R01224,R07168	RC00003,RC00035,RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR
k59_49118_1	1173029.JH980292_gene562	1.25e-08	53.1	COG3288@1|root,COG3288@2|Bacteria,1G711@1117|Cyanobacteria,1HBSJ@1150|Oscillatoriales	1117|Cyanobacteria	C	NAD NADP transhydrogenase alpha subunit	pntA-2	-	1.6.1.2	ko:K00324	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	PNTB_4TM
k59_49118_2	1121406.JAEX01000007_gene2381	8.56e-30	119.0	COG1282@1|root,COG1282@2|Bacteria,1MUP4@1224|Proteobacteria,42NHS@68525|delta/epsilon subdivisions,2WJHI@28221|Deltaproteobacteria,2MAE5@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	NAD(P) transhydrogenase beta subunit	-	-	1.6.1.2	ko:K00325	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	PNTB
k59_201003_1	1095769.CAHF01000021_gene938	2.04e-40	142.0	COG0395@1|root,COG0395@2|Bacteria,1N4I0@1224|Proteobacteria,2VNEK@28216|Betaproteobacteria,477GY@75682|Oxalobacteraceae	28216|Betaproteobacteria	P	ABC-type sugar transport system, permease component	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
k59_201003_2	1394178.AWOO02000071_gene398	1.53e-35	130.0	COG1175@1|root,COG1175@2|Bacteria,2GJGB@201174|Actinobacteria,4EHFE@85012|Streptosporangiales	201174|Actinobacteria	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02025,ko:K15771	ko02010,map02010	M00207,M00491	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.16,3.A.1.1.2	-	-	BPD_transp_1
k59_109976_1	1121403.AUCV01000017_gene4526	7.29e-100	298.0	COG1683@1|root,COG3272@1|root,COG1683@2|Bacteria,COG3272@2|Bacteria,1MXYZ@1224|Proteobacteria,42M4E@68525|delta/epsilon subdivisions,2WKFT@28221|Deltaproteobacteria,2MIBF@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF1722)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1722,DUF523
k59_102559_2	696747.NIES39_M02150	1.59e-14	74.7	COG0745@1|root,COG4191@1|root,COG0745@2|Bacteria,COG4191@2|Bacteria,1G2QN@1117|Cyanobacteria,1H9CA@1150|Oscillatoriales	1117|Cyanobacteria	T	Response regulator receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
k59_87007_1	1304885.AUEY01000036_gene2247	1.59e-88	278.0	COG0591@1|root,COG0591@2|Bacteria,1PNHU@1224|Proteobacteria,43AQ2@68525|delta/epsilon subdivisions,2X63U@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Sodium:solute symporter family	-	-	-	-	-	-	-	-	-	-	-	-	SSF
k59_208809_1	589865.DaAHT2_2137	3.71e-89	273.0	COG0436@1|root,COG0436@2|Bacteria,1MWS8@1224|Proteobacteria,42NH6@68525|delta/epsilon subdivisions,2WJCV@28221|Deltaproteobacteria,2MHTU@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate	dapL	GO:0003674,GO:0003824,GO:0008483,GO:0016740,GO:0016769	2.6.1.83	ko:K10206	ko00300,ko01100,ko01110,ko01130,ko01230,map00300,map01100,map01110,map01130,map01230	M00527	R07613	RC00006,RC01847	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
k59_155655_1	443144.GM21_2260	5.58e-114	337.0	COG0547@1|root,COG0547@2|Bacteria,1MUPV@1224|Proteobacteria,42NRG@68525|delta/epsilon subdivisions,2WJRU@28221|Deltaproteobacteria,43U0Q@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)	trpD	GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.4.2.18,4.1.3.27	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R00985,R00986,R01073	RC00010,RC00440,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2495	GATase,Glycos_trans_3N,Glycos_transf_3
k59_72128_1	1265505.ATUG01000003_gene24	1.04e-110	333.0	COG0436@1|root,COG0436@2|Bacteria,1QW10@1224|Proteobacteria,42MQA@68525|delta/epsilon subdivisions,2WJDK@28221|Deltaproteobacteria,2MJ7D@213118|Desulfobacterales	28221|Deltaproteobacteria	E	PFAM aminotransferase class I and II	bamJ	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
k59_117140_1	402777.KB235903_gene1790	5.08e-08	60.5	COG0661@1|root,COG0661@2|Bacteria,1G1KC@1117|Cyanobacteria,1H816@1150|Oscillatoriales	1117|Cyanobacteria	S	Unusual protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	ABC1
k59_186230_1	335543.Sfum_2531	3.54e-51	175.0	COG1641@1|root,COG1641@2|Bacteria,1MUKU@1224|Proteobacteria,42MHQ@68525|delta/epsilon subdivisions,2WJAC@28221|Deltaproteobacteria,2MRAV@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Belongs to the LarC family	-	-	4.99.1.12	ko:K09121	-	-	-	-	ko00000,ko01000	-	-	-	DUF111
k59_102572_2	570967.JMLV01000023_gene3122	2.97e-09	63.5	COG0637@1|root,COG1877@1|root,COG0637@2|Bacteria,COG1877@2|Bacteria,1RGY2@1224|Proteobacteria,2VFA5@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	Removes the phosphate from trehalose 6-phosphate to produce free trehalose	-	-	3.1.3.12	ko:K01087	ko00500,ko01100,map00500,map01100	-	R02778	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2,Trehalose_PPase
k59_94856_1	926569.ANT_04990	1.5e-25	99.4	COG1662@1|root,COG1662@2|Bacteria	2|Bacteria	L	PFAM IS1 transposase	-	-	-	ko:K07480	-	-	-	-	ko00000	-	-	-	DDE_Tnp_IS1
k59_238623_1	879212.DespoDRAFT_00661	3.13e-74	228.0	COG0217@1|root,COG0217@2|Bacteria,1MW3X@1224|Proteobacteria,42N7Q@68525|delta/epsilon subdivisions,2WJ1I@28221|Deltaproteobacteria,2MIE0@213118|Desulfobacterales	28221|Deltaproteobacteria	K	transcriptional regulatory protein	yebC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
k59_238623_2	502025.Hoch_6720	7.02e-52	172.0	COG0293@1|root,COG0293@2|Bacteria,1MW1C@1224|Proteobacteria,42T4F@68525|delta/epsilon subdivisions,2WP6B@28221|Deltaproteobacteria,2YVEY@29|Myxococcales	28221|Deltaproteobacteria	J	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit	ftsJ	-	2.1.1.166	ko:K02427	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ
k59_208836_1	697284.ERIC2_c17250	8.71e-07	56.2	COG3383@1|root,COG3383@2|Bacteria,1TT6D@1239|Firmicutes,4IS5E@91061|Bacilli,2771U@186822|Paenibacillaceae	91061|Bacilli	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	fdhA	GO:0003674,GO:0003824,GO:0003954,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0048037,GO:0051536,GO:0051540,GO:0055114	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Fer2_4,Fer4,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
k59_34321_1	690850.Desaf_2680	1.86e-68	221.0	COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,42P5W@68525|delta/epsilon subdivisions,2WMA6@28221|Deltaproteobacteria,2M8GP@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	PFAM Peptidase M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
k59_231563_1	546271.Selsp_0546	2.42e-78	244.0	COG1995@1|root,COG1995@2|Bacteria,1TQGT@1239|Firmicutes,4H6P8@909932|Negativicutes	909932|Negativicutes	H	Pyridoxal phosphate biosynthetic protein PdxA	-	-	1.1.1.408,1.1.1.409	ko:K22024	-	-	-	-	ko00000,ko01000	-	-	-	PdxA
k59_147494_1	765913.ThidrDRAFT_0423	1.59e-56	201.0	COG2885@1|root,COG3267@1|root,COG2885@2|Bacteria,COG3267@2|Bacteria,1MU3G@1224|Proteobacteria,1RMI0@1236|Gammaproteobacteria,1WXX2@135613|Chromatiales	135613|Chromatiales	U	SMART AAA ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22,OmpA
k59_26246_1	1458357.BG58_05825	6.46e-55	188.0	COG4584@1|root,COG4584@2|Bacteria,1MU2G@1224|Proteobacteria,2VJIW@28216|Betaproteobacteria,1K2PQ@119060|Burkholderiaceae	28216|Betaproteobacteria	L	PFAM Integrase catalytic region	-	-	-	-	-	-	-	-	-	-	-	-	rve
k59_110026_1	755178.Cyan10605_1928	2.24e-53	180.0	COG2006@1|root,COG2006@2|Bacteria,1G0X0@1117|Cyanobacteria	1117|Cyanobacteria	S	Domain of unknown function (DUF362)	-	-	-	-	-	-	-	-	-	-	-	-	DUF362
k59_26250_1	944479.JQLX01000014_gene1522	3.04e-80	258.0	COG1328@1|root,COG1328@2|Bacteria,1MWMS@1224|Proteobacteria,42M8V@68525|delta/epsilon subdivisions,2WJ7S@28221|Deltaproteobacteria,2M70X@213113|Desulfurellales	28221|Deltaproteobacteria	F	Anaerobic ribonucleoside-triphosphate reductase	nrdD	-	1.1.98.6	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R11633,R11634,R11635,R11636	RC00613	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-cone,NRDD
k59_94869_1	251229.Chro_1292	1.09e-59	192.0	COG3124@1|root,COG3124@2|Bacteria,1GKY3@1117|Cyanobacteria,3VMTC@52604|Pleurocapsales	1117|Cyanobacteria	S	Pfam:DUF479	-	-	-	-	-	-	-	-	-	-	-	-	ACP_PD
k59_231573_1	177437.HRM2_04480	2.81e-71	228.0	COG1150@1|root,COG1150@2|Bacteria,1QUKA@1224|Proteobacteria,42MNE@68525|delta/epsilon subdivisions,2WIN3@28221|Deltaproteobacteria,2MHSC@213118|Desulfobacterales	28221|Deltaproteobacteria	C	4Fe-4S dicluster domain	qmoC	-	-	ko:K16887	-	-	-	-	ko00000	-	-	-	Fer4_17,Fer4_8,Fer4_9,Nitrate_red_gam
k59_87050_2	330214.NIDE1420	2.49e-07	58.9	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF5128,NHL,PA14
k59_117173_1	555779.Dthio_PD1799	1.32e-63	219.0	COG1924@1|root,COG3580@1|root,COG1924@2|Bacteria,COG3580@2|Bacteria,1PKG6@1224|Proteobacteria,42MY4@68525|delta/epsilon subdivisions,2WJFI@28221|Deltaproteobacteria,2M8T9@213115|Desulfovibrionales	28221|Deltaproteobacteria	I	ATPase BadF BadG BcrA BcrD type	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG,DUF2229
k59_208853_1	28229.ND2E_2199	6.2e-55	191.0	COG0616@1|root,COG0616@2|Bacteria,1MUXE@1224|Proteobacteria,1RNYW@1236|Gammaproteobacteria,2Q60H@267889|Colwelliaceae	1236|Gammaproteobacteria	OU	Peptidase family S49	sppA	GO:0003674,GO:0003824,GO:0004175,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006465,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009987,GO:0010467,GO:0016020,GO:0016021,GO:0016485,GO:0016787,GO:0019538,GO:0031224,GO:0031226,GO:0034641,GO:0043170,GO:0043603,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0051604,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564	-	ko:K04773	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S49
k59_94872_1	84531.JMTZ01000038_gene3658	1.79e-30	121.0	COG0076@1|root,COG0076@2|Bacteria,1MX25@1224|Proteobacteria,1RNSQ@1236|Gammaproteobacteria,1XB58@135614|Xanthomonadales	135614|Xanthomonadales	E	Pyridoxal-dependent decarboxylase conserved domain	-	-	4.1.2.27	ko:K01634	ko00600,ko01100,ko04071,map00600,map01100,map04071	M00100	R02464,R06516	RC00264,RC00721,RC01266	ko00000,ko00001,ko00002,ko01000	-	-	-	Pyridoxal_deC
k59_231578_1	748449.Halha_1919	7.07e-65	207.0	COG0569@1|root,COG0569@2|Bacteria,1UD9U@1239|Firmicutes,25HY7@186801|Clostridia,3WBIC@53433|Halanaerobiales	186801|Clostridia	P	PFAM TrkA-N domain	-	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
k59_110036_1	443143.GM18_2831	6.73e-19	91.7	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,Response_reg
k59_125437_1	1121440.AUMA01000011_gene2420	1.98e-32	117.0	2B047@1|root,31SEM@2|Bacteria,1RHZY@1224|Proteobacteria,42V93@68525|delta/epsilon subdivisions,2WVVI@28221|Deltaproteobacteria,2MCS3@213115|Desulfovibrionales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_125437_2	1238182.C882_4460	4.02e-55	179.0	2ATAH@1|root,31ITJ@2|Bacteria,1RIQF@1224|Proteobacteria,2UD6U@28211|Alphaproteobacteria,2JTD0@204441|Rhodospirillales	204441|Rhodospirillales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_117178_1	997346.HMPREF9374_3864	3e-24	105.0	COG2719@1|root,COG2719@2|Bacteria,1TRHQ@1239|Firmicutes,4HBAW@91061|Bacilli,27B1E@186824|Thermoactinomycetaceae	91061|Bacilli	S	SpoVR like protein	spoVR	-	-	ko:K06415	-	-	-	-	ko00000	-	-	-	SpoVR
k59_34346_1	1265505.ATUG01000001_gene3092	5e-79	246.0	COG0607@1|root,COG2897@1|root,COG0607@2|Bacteria,COG2897@2|Bacteria,1MU3V@1224|Proteobacteria,42NRF@68525|delta/epsilon subdivisions,2WJZ6@28221|Deltaproteobacteria,2MKBF@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
k59_208858_1	366602.Caul_5320	0.000119	45.1	COG0642@1|root,COG3300@1|root,COG2205@2|Bacteria,COG3300@2|Bacteria,1NRP8@1224|Proteobacteria,2U4KP@28211|Alphaproteobacteria,2KHUJ@204458|Caulobacterales	204458|Caulobacterales	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,MHYT,PAS_7,Response_reg
k59_208858_2	933262.AXAM01000002_gene551	1.49e-43	151.0	COG4191@1|root,COG4191@2|Bacteria,1NC2K@1224|Proteobacteria,42WDG@68525|delta/epsilon subdivisions,2WRNM@28221|Deltaproteobacteria,2MKFV@213118|Desulfobacterales	28221|Deltaproteobacteria	T	PFAM histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HisKA
k59_234977_1	338966.Ppro_2411	2.43e-52	178.0	COG2177@1|root,COG2177@2|Bacteria,1MU65@1224|Proteobacteria,43BBA@68525|delta/epsilon subdivisions,2X6QG@28221|Deltaproteobacteria,43T0S@69541|Desulfuromonadales	28221|Deltaproteobacteria	D	Part of the ABC transporter FtsEX involved in cellular division	ftsX	-	-	ko:K09811	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	FtsX
k59_136395_1	1499967.BAYZ01000155_gene659	2.63e-18	86.7	COG3829@1|root,COG4251@1|root,COG3829@2|Bacteria,COG4251@2|Bacteria,2NR7U@2323|unclassified Bacteria	2|Bacteria	T	PAS fold	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,HisKA_3,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
k59_105989_1	706587.Desti_3296	4.47e-32	127.0	COG1032@1|root,COG1032@2|Bacteria,1MUMS@1224|Proteobacteria,42QFG@68525|delta/epsilon subdivisions,2WK91@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
k59_158764_1	335543.Sfum_1698	8.07e-90	291.0	COG1205@1|root,COG1205@2|Bacteria,1QU0I@1224|Proteobacteria,42M4R@68525|delta/epsilon subdivisions,2WK1V@28221|Deltaproteobacteria,2MQS2@213462|Syntrophobacterales	28221|Deltaproteobacteria	L	DEAD DEAH box helicase	yprA	-	-	ko:K06877	-	-	-	-	ko00000	-	-	-	DEAD,DUF1998,Helicase_C,RNase_H_2
k59_165828_1	1232437.KL662039_gene2059	5.1e-37	135.0	COG0330@1|root,COG0330@2|Bacteria,1MUM2@1224|Proteobacteria,42NUT@68525|delta/epsilon subdivisions,2WKQX@28221|Deltaproteobacteria,2MI5I@213118|Desulfobacterales	28221|Deltaproteobacteria	O	HflC and HflK could encode or regulate a protease	hflK	-	-	ko:K04088	-	M00742	-	-	ko00000,ko00002,ko01000	-	-	-	Band_7
k59_60491_1	335543.Sfum_0204	4.58e-47	156.0	COG1143@1|root,COG1143@2|Bacteria,1MV90@1224|Proteobacteria,42SZV@68525|delta/epsilon subdivisions,2WP8T@28221|Deltaproteobacteria,2MQJF@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoI	-	1.6.5.3	ko:K00338,ko:K05580	ko00190,ko01100,map00190,map01100	M00144,M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer4,Fer4_4,Fer4_7
k59_29303_1	69279.BG36_03250	2.24e-26	110.0	COG0459@1|root,COG0459@2|Bacteria,1MURR@1224|Proteobacteria,2TS07@28211|Alphaproteobacteria,43HY4@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	-	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
k59_196061_1	96561.Dole_0795	2.56e-46	156.0	COG0517@1|root,COG0517@2|Bacteria,1RKZ2@1224|Proteobacteria,42SYQ@68525|delta/epsilon subdivisions,2WP9E@28221|Deltaproteobacteria,2MK65@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
k59_143928_2	936596.HMPREF1495_1843	3.58e-22	101.0	COG0272@1|root,COG0272@2|Bacteria,1TPQ3@1239|Firmicutes,248AX@186801|Clostridia,1HV5K@1164882|Lachnoanaerobaculum	186801|Clostridia	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	-	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
k59_105998_1	1123373.ATXI01000025_gene777	1.06e-59	199.0	COG2204@1|root,COG2204@2|Bacteria,2GH1I@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	T	Bacterial regulatory protein, Fis family	-	-	-	ko:K13599	ko02020,map02020	M00498	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
k59_136401_1	527002.yaldo0001_25010	6.98e-23	101.0	COG4623@1|root,COG4623@2|Bacteria,1MWDS@1224|Proteobacteria,1RM8W@1236|Gammaproteobacteria,41EUP@629|Yersinia	1236|Gammaproteobacteria	M	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella	mltF	GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0008150,GO:0008152,GO:0008933,GO:0009056,GO:0009057,GO:0009253,GO:0009279,GO:0016020,GO:0016740,GO:0016757,GO:0019867,GO:0030203,GO:0030312,GO:0030313,GO:0031975,GO:0043170,GO:0044462,GO:0044464,GO:0061783,GO:0071704,GO:0071944,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575	-	ko:K18691	-	-	-	-	ko00000,ko01000,ko01011	-	-	iBWG_1329.BWG_2322,iEC042_1314.EC042_2762,iECDH1ME8569_1439.ECDH1ME8569_2485,iECNA114_1301.ECNA114_2631,iECP_1309.ECP_2560,iECSF_1327.ECSF_2397,iECW_1372.ECW_m2786,iEKO11_1354.EKO11_1175,iEcDH1_1363.EcDH1_1110,iEcHS_1320.EcHS_A2711,iEcolC_1368.EcolC_1119,iG2583_1286.G2583_3089,iJO1366.b2558,iSFxv_1172.SFxv_2861,iUMN146_1321.UM146_03930,iUMNK88_1353.UMNK88_3212,iUTI89_1310.UTI89_C2878,iWFL_1372.ECW_m2786,iY75_1357.Y75_RS13345	SBP_bac_3,SLT
k59_6107_1	443144.GM21_0890	1.2e-48	161.0	COG1636@1|root,COG1636@2|Bacteria,1MUG5@1224|Proteobacteria,42M1E@68525|delta/epsilon subdivisions,2WMR5@28221|Deltaproteobacteria,43UNP@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)	queH	-	1.17.99.6	ko:K09765	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF208
k59_90587_1	1121405.dsmv_0636	4.57e-67	219.0	COG1252@1|root,COG1252@2|Bacteria,1QUKT@1224|Proteobacteria,42MAW@68525|delta/epsilon subdivisions,2WJCB@28221|Deltaproteobacteria,2MHYK@213118|Desulfobacterales	28221|Deltaproteobacteria	C	TIGRFAM Pyridine nucleotide-disulfide oxidoreductase family protein	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2
k59_90588_1	8479.XP_005292063.2	0.000375	49.3	COG5021@1|root,KOG0941@2759|Eukaryota,38E5N@33154|Opisthokonta,3BEHG@33208|Metazoa,3CVCG@33213|Bilateria,48AU0@7711|Chordata,495CF@7742|Vertebrata,4CJEX@8459|Testudines	33208|Metazoa	O	HECT and RLD domain containing E3 ubiquitin protein ligase family member 6	HERC5	GO:0000079,GO:0000209,GO:0001817,GO:0001818,GO:0001932,GO:0002244,GO:0002376,GO:0002520,GO:0002682,GO:0002697,GO:0002831,GO:0003674,GO:0003824,GO:0004842,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005829,GO:0006464,GO:0006807,GO:0007275,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009617,GO:0009987,GO:0016567,GO:0016740,GO:0019220,GO:0019222,GO:0019538,GO:0019787,GO:0030097,GO:0030154,GO:0030332,GO:0031323,GO:0031347,GO:0031399,GO:0032020,GO:0032101,GO:0032268,GO:0032446,GO:0032479,GO:0032480,GO:0032501,GO:0032502,GO:0036211,GO:0042296,GO:0042325,GO:0043170,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043412,GO:0043549,GO:0043900,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0045859,GO:0048513,GO:0048519,GO:0048534,GO:0048583,GO:0048731,GO:0048856,GO:0048869,GO:0050688,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051171,GO:0051174,GO:0051239,GO:0051241,GO:0051246,GO:0051338,GO:0051704,GO:0051707,GO:0051726,GO:0060255,GO:0061630,GO:0061659,GO:0065007,GO:0065009,GO:0070647,GO:0071704,GO:0071900,GO:0080090,GO:0080134,GO:0140096,GO:1901564,GO:1904029	-	ko:K22372	-	-	-	-	ko00000,ko01000,ko04121	-	-	-	HECT,RCC1
k59_150656_1	639282.DEFDS_1273	1.77e-49	169.0	COG0457@1|root,COG0457@2|Bacteria,2GFWS@200930|Deferribacteres	200930|Deferribacteres	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_128590_1	359.CN09_25960	2.14e-91	279.0	COG3344@1|root,COG3344@2|Bacteria,1MVI1@1224|Proteobacteria,2U28T@28211|Alphaproteobacteria,4BE1X@82115|Rhizobiaceae	28211|Alphaproteobacteria	L	PFAM RNA-directed DNA polymerase (Reverse transcriptase)	-	-	2.7.7.49	ko:K00986	-	-	-	-	ko00000,ko01000	-	-	-	GIIM,RVT_1
k59_52227_1	999413.HMPREF1094_03803	1.31e-07	55.8	COG3910@1|root,COG3910@2|Bacteria,1TSWP@1239|Firmicutes,3VQ94@526524|Erysipelotrichia	526524|Erysipelotrichia	S	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_21,AAA_23
k59_143943_1	936573.HMPREF1147_2351	1.34e-44	160.0	COG0438@1|root,COG0438@2|Bacteria,1UWIQ@1239|Firmicutes,4H8GD@909932|Negativicutes	909932|Negativicutes	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4
k59_29328_1	933262.AXAM01000006_gene1840	7.47e-66	210.0	COG0484@1|root,COG0484@2|Bacteria,1MUZ4@1224|Proteobacteria,42NBY@68525|delta/epsilon subdivisions,2WJV2@28221|Deltaproteobacteria,2MIIH@213118|Desulfobacterales	28221|Deltaproteobacteria	O	heat shock protein DnaJ domain protein	-	-	-	ko:K03686,ko:K05516	-	-	-	-	ko00000,ko03029,ko03036,ko03110	-	-	-	DnaJ,DnaJ_C
k59_226794_1	1265505.ATUG01000001_gene3897	3.35e-31	122.0	COG0277@1|root,COG0277@2|Bacteria,1MU6Y@1224|Proteobacteria,42YJQ@68525|delta/epsilon subdivisions,2WTJP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	FAD linked oxidases, C-terminal domain	-	-	1.1.3.15	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
k59_158778_1	443143.GM18_3369	8.11e-57	191.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WJ88@28221|Deltaproteobacteria,43TKB@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	response regulator	ntrX	-	-	ko:K13599	ko02020,map02020	M00498	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
k59_150659_1	717606.PaecuDRAFT_2993	2.16e-10	62.0	COG0745@1|root,COG0745@2|Bacteria,1TS81@1239|Firmicutes,4HEGD@91061|Bacilli,26TR8@186822|Paenibacillaceae	91061|Bacilli	T	Transcriptional regulator	mprA1	-	-	ko:K07669	ko02020,map02020	M00460	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
k59_83124_1	485915.Dret_0226	4.98e-121	375.0	COG0243@1|root,COG3383@1|root,COG0243@2|Bacteria,COG3383@2|Bacteria,1MW3N@1224|Proteobacteria,43BJY@68525|delta/epsilon subdivisions,2WIWD@28221|Deltaproteobacteria,2M9AS@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	Formate dehydrogenase, alpha subunit	fdnG-2	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding,TAT_signal
k59_106032_1	1265505.ATUG01000002_gene1976	1.73e-44	152.0	COG4120@1|root,COG4120@2|Bacteria,1MXGE@1224|Proteobacteria,42P9P@68525|delta/epsilon subdivisions,2WJPI@28221|Deltaproteobacteria,2MJS5@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Branched-chain amino acid transport system / permease component	-	-	-	ko:K01989,ko:K05832	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_sub_bind,BPD_transp_2
k59_106032_2	311403.Arad_3527	0.000169	45.1	COG1116@1|root,COG1116@2|Bacteria,1MUIM@1224|Proteobacteria,2TRHM@28211|Alphaproteobacteria,4BBTT@82115|Rhizobiaceae	28211|Alphaproteobacteria	P	ABC transporter	-	-	-	ko:K02049	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	ABC_tran
k59_128616_1	96561.Dole_2401	4.76e-67	218.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WJKZ@28221|Deltaproteobacteria,2MI48@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Bacterial regulatory protein, Fis family	-	-	-	ko:K07713	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
k59_21975_1	247490.KSU1_B0405	1.05e-13	68.2	COG1765@1|root,COG1765@2|Bacteria	2|Bacteria	O	OsmC-like protein	-	-	-	-	-	-	-	-	-	-	-	-	OsmC
k59_173894_2	1121382.JQKG01000002_gene4539	1.85e-14	73.2	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
k59_106042_1	1307759.JOMJ01000003_gene1359	1.88e-87	270.0	COG1875@1|root,COG1875@2|Bacteria,1MUX1@1224|Proteobacteria,42MK9@68525|delta/epsilon subdivisions,2WJ1C@28221|Deltaproteobacteria,2M8GR@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	SMART Nucleotide binding protein, PINc	phoH1	-	-	ko:K07175	-	-	-	-	ko00000	-	-	-	PIN_4,PhoH
k59_113549_1	1121468.AUBR01000019_gene2638	1.59e-83	255.0	COG0123@1|root,COG0123@2|Bacteria,1VX2J@1239|Firmicutes,251VB@186801|Clostridia	186801|Clostridia	BQ	Histone deacetylase domain	-	-	-	-	-	-	-	-	-	-	-	-	Hist_deacetyl
k59_90617_1	933262.AXAM01000044_gene1408	4.24e-107	320.0	COG3385@1|root,COG3385@2|Bacteria,1MVRM@1224|Proteobacteria,42U5W@68525|delta/epsilon subdivisions,2WQUQ@28221|Deltaproteobacteria,2MKFC@213118|Desulfobacterales	28221|Deltaproteobacteria	L	PFAM transposase IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,Nterm_IS4
k59_219179_2	1121405.dsmv_0116	8.65e-64	198.0	COG0426@1|root,COG0426@2|Bacteria,1RKK1@1224|Proteobacteria,42RRR@68525|delta/epsilon subdivisions,2WP60@28221|Deltaproteobacteria,2MK3X@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Flavodoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	Flavodoxin_5
k59_204385_1	143224.JQMD01000002_gene3430	1.05e-135	400.0	COG2160@1|root,COG2160@2|Bacteria,4NHGG@976|Bacteroidetes,1HYCR@117743|Flavobacteriia	976|Bacteroidetes	G	Catalyzes the conversion of L-arabinose to L-ribulose	araA	-	5.3.1.4	ko:K01804	ko00040,ko01100,map00040,map01100	-	R01761	RC00516	ko00000,ko00001,ko01000	-	-	-	Arabinose_Iso_C,Arabinose_Isome
k59_204386_1	469381.Dpep_1250	6.92e-40	149.0	COG4907@1|root,COG4907@2|Bacteria,3TA8F@508458|Synergistetes	508458|Synergistetes	S	membrane protein (DUF2207)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2207
k59_173903_1	998674.ATTE01000001_gene3217	1.5e-29	113.0	COG1024@1|root,COG1024@2|Bacteria,1MWZC@1224|Proteobacteria,1S32J@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	paaF	-	4.2.1.17	ko:K01715	ko00650,ko01200,map00650,map01200	-	R03026	RC00831	ko00000,ko00001,ko01000	-	-	-	ECH_1
k59_136434_1	1048339.KB913029_gene4723	4.5e-100	305.0	COG0388@1|root,COG0388@2|Bacteria,2H03Y@201174|Actinobacteria,4EVT7@85013|Frankiales	201174|Actinobacteria	S	Carbon-nitrogen hydrolase	-	-	3.5.5.1	ko:K01501	ko00380,ko00460,ko00627,ko00643,ko00910,ko01120,map00380,map00460,map00627,map00643,map00910,map01120	-	R00540,R01887,R03093,R03542,R05591,R07855	RC00315,RC00325,RC00617,RC00959,RC02811	ko00000,ko00001,ko01000	-	-	-	CN_hydrolase
k59_136434_3	713587.THITH_03965	7.91e-26	103.0	COG1416@1|root,COG1416@2|Bacteria,1N64N@1224|Proteobacteria,1SNQX@1236|Gammaproteobacteria,1X1RU@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DrsE
k59_143956_1	118168.MC7420_7704	6.96e-09	62.0	COG0515@1|root,COG2203@1|root,COG3899@1|root,COG4251@1|root,COG0515@2|Bacteria,COG2203@2|Bacteria,COG3899@2|Bacteria,COG4251@2|Bacteria,1GHS3@1117|Cyanobacteria,1HF2M@1150|Oscillatoriales	1117|Cyanobacteria	KLT	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GAF,Pkinase
k59_136437_1	591158.SSMG_02159	1.15e-51	176.0	COG0183@1|root,COG0183@2|Bacteria,2GJAC@201174|Actinobacteria	201174|Actinobacteria	I	Belongs to the thiolase family	fadA	-	2.3.1.16,2.3.1.9	ko:K00626,ko:K00632	ko00071,ko00072,ko00280,ko00281,ko00310,ko00362,ko00380,ko00592,ko00620,ko00630,ko00640,ko00642,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00281,map00310,map00362,map00380,map00592,map00620,map00630,map00640,map00642,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00087,M00088,M00095,M00113,M00373,M00374,M00375	R00238,R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
k59_196100_1	1297617.JPJD01000016_gene126	6.81e-77	252.0	COG1574@1|root,COG1574@2|Bacteria,1TQ6G@1239|Firmicutes,24A5F@186801|Clostridia,268Q9@186813|unclassified Clostridiales	186801|Clostridia	S	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
k59_241778_1	706587.Desti_4880	8.76e-07	50.4	COG2128@1|root,COG2128@2|Bacteria,1RHU7@1224|Proteobacteria,42USP@68525|delta/epsilon subdivisions,2WR2Q@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_173914_1	335543.Sfum_2791	8.91e-60	190.0	COG0353@1|root,COG0353@2|Bacteria,1MV9Q@1224|Proteobacteria,42QZJ@68525|delta/epsilon subdivisions,2WNCH@28221|Deltaproteobacteria,2MRIN@213462|Syntrophobacterales	28221|Deltaproteobacteria	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecR,Toprim_4
k59_212208_1	335543.Sfum_1942	1.57e-111	342.0	COG0377@1|root,COG0649@1|root,COG0852@1|root,COG0377@2|Bacteria,COG0649@2|Bacteria,COG0852@2|Bacteria,1MVIN@1224|Proteobacteria,42M9G@68525|delta/epsilon subdivisions,2WIS7@28221|Deltaproteobacteria,2MR1T@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoBCD	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072521,GO:1901135,GO:1901360,GO:1901564	1.6.5.3	ko:K00333,ko:K13378,ko:K13380	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa,Complex1_49kDa,Oxidored_q6
k59_150675_1	335543.Sfum_2578	3.39e-95	292.0	COG1418@1|root,COG1418@2|Bacteria,1P7YA@1224|Proteobacteria,42KZ8@68525|delta/epsilon subdivisions,2WJG1@28221|Deltaproteobacteria,2MQ65@213462|Syntrophobacterales	28221|Deltaproteobacteria	A	Endoribonuclease that initiates mRNA decay	rny	-	-	ko:K18682	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DUF3552,HD,KH_1
k59_44587_1	269799.Gmet_0274	2.36e-62	216.0	COG3523@1|root,COG3523@2|Bacteria,1MV3D@1224|Proteobacteria,42PG2@68525|delta/epsilon subdivisions,2WM2G@28221|Deltaproteobacteria,43UWY@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	ImcF-related N-terminal domain	tssM	-	-	ko:K11891	ko02025,ko03070,map02025,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	IcmF-related,IcmF_C,ImcF-related_N
k59_204406_1	1114922.CIFAM_12_02280	3.46e-54	175.0	COG0454@1|root,COG0454@2|Bacteria,1RD5R@1224|Proteobacteria,1S4R5@1236|Gammaproteobacteria,3WZ02@544|Citrobacter	1236|Gammaproteobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
k59_173919_1	247490.KSU1_C0752	5.5e-42	152.0	COG1488@1|root,COG1488@2|Bacteria,2IXDA@203682|Planctomycetes	203682|Planctomycetes	F	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP	-	-	6.3.4.21	ko:K00763	ko00760,ko01100,map00760,map01100	-	R01724	RC00033	ko00000,ko00001,ko01000	-	-	-	NAPRTase
k59_143974_1	1444711.CCJF01000005_gene1297	3.68e-64	201.0	COG1182@1|root,COG1182@2|Bacteria	2|Bacteria	I	oxidoreductase activity, acting on other nitrogenous compounds as donors	azoR	GO:0003674,GO:0003824,GO:0006082,GO:0006629,GO:0006631,GO:0008081,GO:0008150,GO:0008152,GO:0008770,GO:0009987,GO:0016787,GO:0016788,GO:0019752,GO:0032787,GO:0042578,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0071704,GO:0140096	-	ko:K01118	-	-	-	-	ko00000,ko01000	-	-	-	Flavodoxin_2
k59_143974_2	340177.Cag_1368	1.93e-05	47.4	2DIJ9@1|root,303FS@2|Bacteria,1FFE5@1090|Chlorobi	1090|Chlorobi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_158829_1	98439.AJLL01000090_gene133	8.17e-14	74.3	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1G09B@1117|Cyanobacteria,1JJEC@1189|Stigonemataceae	1117|Cyanobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	HAMP,HATPase_c,HisKA,Response_reg,dCache_1
k59_190078_1	177437.HRM2_22250	1.93e-95	287.0	COG0501@1|root,COG0501@2|Bacteria,1MUV4@1224|Proteobacteria,42MEE@68525|delta/epsilon subdivisions,2WJYV@28221|Deltaproteobacteria,2MJ0G@213118|Desulfobacterales	28221|Deltaproteobacteria	O	Belongs to the peptidase M48B family	htpX	-	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	Peptidase_M48
k59_566_1	1541960.KQ78_02238	2.66e-48	177.0	COG0419@1|root,COG0419@2|Bacteria	2|Bacteria	L	ATPase involved in DNA repair	-	-	-	ko:K02057,ko:K03546	-	M00221	-	-	ko00000,ko00002,ko02000,ko03400	3.A.1.2	-	-	AAA_23,BPD_transp_2,HATPase_c,PAS_10
k59_91509_1	439235.Dalk_5190	1.39e-56	189.0	COG3547@1|root,COG3547@2|Bacteria,1NCHY@1224|Proteobacteria,42TM4@68525|delta/epsilon subdivisions,2WR4U@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	PFAM transposase IS116 IS110 IS902 family	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_212782_1	1131730.BAVI_09741	9.45e-51	171.0	COG0334@1|root,COG0334@2|Bacteria,1TQU2@1239|Firmicutes,4HAB2@91061|Bacilli,1ZB55@1386|Bacillus	91061|Bacilli	E	Belongs to the Glu Leu Phe Val dehydrogenases family	-	-	1.4.1.20	ko:K00270	ko00350,ko00360,ko00400,ko01100,ko01110,ko01130,map00350,map00360,map00400,map01100,map01110,map01130	-	R00688,R09830	RC00006	ko00000,ko00001,ko01000	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
k59_212782_2	1147.D082_28900	4.72e-17	81.6	COG0129@1|root,COG0129@2|Bacteria,1G0KD@1117|Cyanobacteria,1H53C@1142|Synechocystis	1117|Cyanobacteria	E	Dehydratase family	ilvD	GO:0003674,GO:0003824,GO:0004160,GO:0016829,GO:0016835,GO:0016836	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
k59_573_1	485913.Krac_5581	1.7e-37	138.0	COG0604@1|root,COG0604@2|Bacteria	2|Bacteria	C	NADPH:quinone reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N,ADH_zinc_N_2
k59_129461_1	1121918.ARWE01000001_gene2173	3.32e-106	337.0	COG2203@1|root,COG2206@1|root,COG2203@2|Bacteria,COG2206@2|Bacteria,1RAQS@1224|Proteobacteria	1224|Proteobacteria	T	metal-dependent phosphohydrolase, HD sub domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HAMP,HD,HD_5
k59_23360_1	1519439.JPJG01000023_gene540	2.91e-23	98.2	COG1924@1|root,COG1924@2|Bacteria,1TQSD@1239|Firmicutes,2481W@186801|Clostridia,2N70I@216572|Oscillospiraceae	186801|Clostridia	I	BadF/BadG/BcrA/BcrD ATPase family	hgdC	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG
k59_220589_1	880072.Desac_2134	6.52e-79	245.0	COG0811@1|root,COG0811@2|Bacteria,1NCWW@1224|Proteobacteria,42PKF@68525|delta/epsilon subdivisions,2WNQ4@28221|Deltaproteobacteria,2MQFV@213462|Syntrophobacterales	28221|Deltaproteobacteria	U	PFAM MotA TolQ ExbB proton channel	aglX	-	-	ko:K03562	ko01120,map01120	-	-	-	ko00000,ko02000	1.A.30.2.2	-	-	MotA_ExbB
k59_76445_1	113395.AXAI01000001_gene3184	1.92e-39	141.0	COG1566@1|root,COG1566@2|Bacteria,1MWG0@1224|Proteobacteria,2TRI4@28211|Alphaproteobacteria,3K2AG@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	V	Biotin-lipoyl like	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3
k59_175032_1	378806.STAUR_4661	1.33e-23	105.0	COG0557@1|root,COG0557@2|Bacteria,1MUS6@1224|Proteobacteria,42NGS@68525|delta/epsilon subdivisions,2WIWF@28221|Deltaproteobacteria,2YUMB@29|Myxococcales	28221|Deltaproteobacteria	J	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs	rnr	-	-	ko:K12573	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	OB_RNB,RNB,S1
k59_15746_1	1049564.TevJSym_ac00500	8.81e-60	205.0	COG1523@1|root,COG1523@2|Bacteria,1MU19@1224|Proteobacteria,1RP6F@1236|Gammaproteobacteria,1J77P@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	G	Carbohydrate-binding module 48 (Isoamylase N-terminal domain)	glgX	-	3.2.1.41,3.2.1.68	ko:K01200,ko:K01214	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02111,R09995,R11261	-	ko00000,ko00001,ko00002,ko01000	-	CBM48,GH13	-	Alpha-amylase,CBM_48
k59_212789_1	56780.SYN_02214	1.2e-191	545.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	two component, sigma54 specific, transcriptional regulator, Fis family	-	-	-	ko:K02481,ko:K07713	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
k59_91534_1	1304885.AUEY01000001_gene3189	9.48e-117	345.0	COG5557@1|root,COG5557@2|Bacteria,1MWYI@1224|Proteobacteria,42P2Q@68525|delta/epsilon subdivisions,2WKC2@28221|Deltaproteobacteria,2MJCP@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM Polysulphide reductase, NrfD	hmcC	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	NrfD
k59_190099_1	1499967.BAYZ01000136_gene57	1.01e-20	84.3	2EUYT@1|root,33NE0@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_198854_1	1123355.JHYO01000030_gene359	1.32e-32	121.0	COG1142@1|root,COG1142@2|Bacteria,1QWC6@1224|Proteobacteria,2TXIR@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	4Fe-4S dicluster domain	-	-	-	ko:K00196,ko:K05796	ko00633,ko00680,ko00720,ko01120,ko01200,map00633,map00680,map00720,map01120,map01200	-	R07157,R08034	RC00250,RC02800	ko00000,ko00001	-	-	-	Fer4_4,Fer4_9
k59_77658_1	760568.Desku_1348	2.66e-42	150.0	COG2301@1|root,COG2301@2|Bacteria,1TPDY@1239|Firmicutes,24AIH@186801|Clostridia,260C4@186807|Peptococcaceae	186801|Clostridia	G	Belongs to the HpcH HpaI aldolase family	-	-	4.1.3.34	ko:K01644	ko02020,map02020	-	R00362	RC00067,RC01118	ko00000,ko00001,ko01000	-	-	-	HpcH_HpaI
k59_123074_1	871968.DESME_03395	9.37e-55	184.0	COG4974@1|root,COG4974@2|Bacteria,1TR57@1239|Firmicutes,24ACW@186801|Clostridia,26128@186807|Peptococcaceae	186801|Clostridia	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
k59_77663_1	397291.C804_03910	2.7e-47	171.0	COG2304@1|root,COG2304@2|Bacteria,1UZGD@1239|Firmicutes,24A6F@186801|Clostridia,27JXI@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Vault protein inter-alpha-trypsin domain	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VIT,VWA_3
k59_145763_1	1095769.CAHF01000023_gene566	4.47e-100	305.0	COG0677@1|root,COG0677@2|Bacteria,1MUC6@1224|Proteobacteria,2VJ7A@28216|Betaproteobacteria,4763B@75682|Oxalobacteraceae	28216|Betaproteobacteria	M	UDP binding domain	-	-	1.1.1.136	ko:K13015	ko00520,map00520	-	R00421	RC00291	ko00000,ko00001,ko01000,ko01005	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
k59_92606_1	984262.SGRA_0639	6.8e-87	267.0	COG0156@1|root,COG0156@2|Bacteria,4NFBU@976|Bacteroidetes,1IP7S@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA	kbl	-	2.3.1.29	ko:K00639	ko00260,map00260	-	R00371	RC00004,RC00394	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
k59_191236_1	1232437.KL662058_gene3950	2.5e-19	94.0	COG0745@1|root,COG1148@1|root,COG0745@2|Bacteria,COG1148@2|Bacteria,1QUM4@1224|Proteobacteria,42MPP@68525|delta/epsilon subdivisions,2WJ3U@28221|Deltaproteobacteria,2MI9Y@213118|Desulfobacterales	28221|Deltaproteobacteria	CT	NAD(P)-binding Rossmann-like domain	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,FAD_oxidored,Fer4,Fer4_7,NAD_binding_8,Pyr_redox_2,Response_reg
k59_191236_2	1411685.U062_01015	0.000649	43.1	COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,1SKTW@1236|Gammaproteobacteria,1J4QE@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	T	COG0642 Signal transduction histidine kinase	-	-	2.7.13.3	ko:K07678	ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111	M00475	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF2222,HAMP,HATPase_c,HisKA,Hpt,PAS_4,Response_reg
k59_107756_1	879212.DespoDRAFT_01357	6.32e-22	94.4	COG0210@1|root,COG1379@1|root,COG0210@2|Bacteria,COG1379@2|Bacteria,1MU0G@1224|Proteobacteria,42MKU@68525|delta/epsilon subdivisions,2WJR3@28221|Deltaproteobacteria,2MIS3@213118|Desulfobacterales	28221|Deltaproteobacteria	L	PFAM UvrD REP helicase	-	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
k59_107756_2	76114.ebA166	1.5e-33	135.0	COG2176@1|root,COG5000@1|root,COG2176@2|Bacteria,COG5000@2|Bacteria,1QUVW@1224|Proteobacteria,2VHZ3@28216|Betaproteobacteria,2KUQR@206389|Rhodocyclales	206389|Rhodocyclales	L	DNA polymerase III	-	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	RNase_T
k59_229157_1	933262.AXAM01000058_gene3196	3.39e-61	211.0	COG0574@1|root,COG0745@1|root,COG0574@2|Bacteria,COG0745@2|Bacteria,1N38V@1224|Proteobacteria,42MWC@68525|delta/epsilon subdivisions,2WKAZ@28221|Deltaproteobacteria,2MICZ@213118|Desulfobacterales	28221|Deltaproteobacteria	GT	pyruvate phosphate dikinase	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_2,PPDK_N
k59_168378_1	880072.Desac_0432	7.85e-78	243.0	COG0589@1|root,COG0589@2|Bacteria	2|Bacteria	T	AMP binding	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIAA-like,Usp
k59_138281_1	335543.Sfum_1753	3.44e-38	143.0	COG3225@1|root,COG3225@2|Bacteria,1MUXW@1224|Proteobacteria,42MRY@68525|delta/epsilon subdivisions,2WJ4F@28221|Deltaproteobacteria,2MRB3@213462|Syntrophobacterales	28221|Deltaproteobacteria	P	transport system involved in gliding motility auxiliary component-like	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC_transp_aux
k59_39674_1	1127673.GLIP_2642	5.66e-14	80.9	COG5616@1|root,COG5616@2|Bacteria,1NSKC@1224|Proteobacteria,1S0KQ@1236|Gammaproteobacteria,46CJK@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	cAMP biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_229159_2	56780.SYN_02149	1.01e-35	135.0	COG0621@1|root,COG0621@2|Bacteria,1MURS@1224|Proteobacteria,42MQ3@68525|delta/epsilon subdivisions,2WJEE@28221|Deltaproteobacteria,2MQ4C@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
k59_176088_1	335543.Sfum_0354	2.6e-119	352.0	COG1180@1|root,COG1180@2|Bacteria,1NQC1@1224|Proteobacteria,42N7U@68525|delta/epsilon subdivisions,2WJ81@28221|Deltaproteobacteria,2MQ4H@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	PFAM Radical SAM	-	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
k59_54813_1	290318.Cvib_1161	1.03e-24	105.0	COG1729@1|root,COG1729@2|Bacteria,1FF3K@1090|Chlorobi	1090|Chlorobi	S	TIGRFAM tol-pal system protein YbgF	-	-	-	-	-	-	-	-	-	-	-	-	TPR_6
k59_213908_1	1265505.ATUG01000001_gene4240	4.71e-84	273.0	COG2208@1|root,COG3287@1|root,COG3290@1|root,COG2208@2|Bacteria,COG3287@2|Bacteria,COG3290@2|Bacteria,1RCHY@1224|Proteobacteria,42R1G@68525|delta/epsilon subdivisions,2WMR7@28221|Deltaproteobacteria,2MJNU@213118|Desulfobacterales	28221|Deltaproteobacteria	T	protein phosphatase 2C domain protein	rsbP	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	PAS,PAS_3,PAS_9,SpoIIE
k59_236753_1	1068978.AMETH_4630	5.72e-38	142.0	COG1804@1|root,COG1804@2|Bacteria,2GIU7@201174|Actinobacteria,4DYSZ@85010|Pseudonocardiales	201174|Actinobacteria	C	PFAM CoA-transferase family III	frc	-	2.8.3.15,2.8.3.16,2.8.3.19	ko:K07544,ko:K07749,ko:K18702	ko00623,ko01100,ko01120,ko01220,map00623,map01100,map01120,map01220	M00418	R05588	RC00014,RC00137	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_transf_3
k59_198877_1	1458357.BG58_16985	7.36e-64	214.0	COG4974@1|root,COG4974@2|Bacteria,1QUHS@1224|Proteobacteria,2VM8C@28216|Betaproteobacteria,1K7IE@119060|Burkholderiaceae	28216|Betaproteobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_1,Phage_integrase
k59_84998_1	643648.Slip_0830	1.91e-45	154.0	COG0778@1|root,COG0778@2|Bacteria,1V4UA@1239|Firmicutes,24EVR@186801|Clostridia,42K9E@68298|Syntrophomonadaceae	186801|Clostridia	C	PFAM Nitroreductase	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
k59_84998_2	1232437.KL662015_gene1247	4.68e-10	60.1	COG2203@1|root,COG2204@1|root,COG3437@1|root,COG4191@1|root,COG2203@2|Bacteria,COG2204@2|Bacteria,COG3437@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MC4@68525|delta/epsilon subdivisions,2WIZU@28221|Deltaproteobacteria,2MJ2F@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	ABC_sub_bind,GAF_2,HATPase_c,HisKA,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg,sCache_2
k59_206504_2	525898.Sdel_1116	7.15e-34	119.0	COG3616@1|root,COG3616@2|Bacteria,1N160@1224|Proteobacteria	1224|Proteobacteria	E	Single-stranded DNA endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DUF2958
k59_183585_1	96561.Dole_2844	6.22e-55	195.0	COG4775@1|root,COG4775@2|Bacteria,1MU0D@1224|Proteobacteria,42MMA@68525|delta/epsilon subdivisions,2WIZB@28221|Deltaproteobacteria,2MIBK@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamA	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
k59_206505_1	986075.CathTA2_2481	4.29e-15	77.0	COG4177@1|root,COG4177@2|Bacteria,1TPMZ@1239|Firmicutes,4HE1X@91061|Bacilli	91061|Bacilli	P	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
k59_206505_2	335543.Sfum_4070	1.49e-35	130.0	COG0559@1|root,COG0559@2|Bacteria,1MU25@1224|Proteobacteria,42MKP@68525|delta/epsilon subdivisions,2WJU9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
k59_191259_1	880072.Desac_1859	2.51e-101	303.0	COG0462@1|root,COG0462@2|Bacteria,1MW21@1224|Proteobacteria,42MI2@68525|delta/epsilon subdivisions,2WJ5W@28221|Deltaproteobacteria,2MR0A@213462|Syntrophobacterales	28221|Deltaproteobacteria	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	prs	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2848	Pribosyl_synth,Pribosyltran_N
k59_9305_1	502025.Hoch_3156	2.24e-28	110.0	2E13Z@1|root,32WJ8@2|Bacteria,1NYI6@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_54828_1	555779.Dthio_PD3833	4.29e-65	217.0	COG3316@1|root,COG3316@2|Bacteria,1RHKZ@1224|Proteobacteria,43CRI@68525|delta/epsilon subdivisions,2X7Z7@28221|Deltaproteobacteria,2MHE3@213115|Desulfovibrionales	28221|Deltaproteobacteria	L	PFAM transposase IS66	-	-	-	ko:K07484	-	-	-	-	ko00000	-	-	-	DDE_Tnp_IS66,DDE_Tnp_IS66_C,LZ_Tnp_IS66,zf-IS66
k59_62498_2	1121403.AUCV01000005_gene216	2.77e-157	462.0	COG0243@1|root,COG0243@2|Bacteria,1NR6J@1224|Proteobacteria,43BMM@68525|delta/epsilon subdivisions,2WJJV@28221|Deltaproteobacteria,2MHWI@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
k59_168400_1	868131.MSWAN_0847	3.06e-33	122.0	COG3369@1|root,arCOG03174@2157|Archaea,2XX0Q@28890|Euryarchaeota	28890|Euryarchaeota	S	SMART zinc finger, CDGSH-type domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_19,zf-CDGSH
k59_9311_1	472759.Nhal_2152	1.03e-95	290.0	COG1071@1|root,COG1071@2|Bacteria,1MU5R@1224|Proteobacteria,1RREX@1236|Gammaproteobacteria,1X25G@135613|Chromatiales	135613|Chromatiales	C	Dehydrogenase E1 component	-	-	1.2.4.1	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh
k59_176105_1	768706.Desor_0848	1.6e-71	230.0	COG2368@1|root,COG2368@2|Bacteria,1TQ70@1239|Firmicutes,248RP@186801|Clostridia,266YR@186807|Peptococcaceae	186801|Clostridia	Q	4-hydroxyphenylacetate 3-hydroxylase C terminal	-	-	1.14.14.9,4.2.1.120,5.3.3.3	ko:K00483,ko:K14534	ko00350,ko00650,ko00720,ko01100,ko01120,ko01200,ko01220,map00350,map00650,map00720,map01100,map01120,map01200,map01220	M00374,M00375	R02698,R03031,R03299,R10782	RC00046,RC01857,RC03277	ko00000,ko00001,ko00002,ko01000	-	-	-	HpaB,HpaB_N
k59_100363_1	1046714.AMRX01000006_gene2878	2.69e-16	78.6	COG3279@1|root,COG3279@2|Bacteria,1MUE8@1224|Proteobacteria,1RMJJ@1236|Gammaproteobacteria,46B1W@72275|Alteromonadaceae	1236|Gammaproteobacteria	KT	LytTr DNA-binding domain	-	-	-	ko:K02477	-	-	-	-	ko00000,ko02022	-	-	-	LytTR,Response_reg
k59_138300_1	384765.SIAM614_02541	1.36e-20	93.2	COG1289@1|root,COG1289@2|Bacteria	2|Bacteria	S	transmembrane transporter activity	VPA1578	-	-	-	-	-	-	-	-	-	-	-	FUSC
k59_9316_1	335543.Sfum_2687	2.47e-109	331.0	COG2759@1|root,COG2759@2|Bacteria,1MUR8@1224|Proteobacteria,42MKE@68525|delta/epsilon subdivisions,2WJF1@28221|Deltaproteobacteria,2MR3P@213462|Syntrophobacterales	28221|Deltaproteobacteria	F	PFAM Formate--tetrahydrofolate ligase	fhs	-	6.3.4.3	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R00943	RC00026,RC00111	ko00000,ko00001,ko00002,ko01000	-	-	-	FTHFS
k59_168409_1	933262.AXAM01000048_gene2601	2.72e-75	249.0	COG2937@1|root,COG2937@2|Bacteria,1MWZ6@1224|Proteobacteria,42MN4@68525|delta/epsilon subdivisions,2WJJ5@28221|Deltaproteobacteria,2MHRG@213118|Desulfobacterales	28221|Deltaproteobacteria	I	Belongs to the GPAT DAPAT family	plsB	-	2.3.1.15	ko:K00631	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
k59_198901_1	1232437.KL662073_gene1734	2.79e-66	213.0	COG2199@1|root,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,43BSG@68525|delta/epsilon subdivisions,2WM56@28221|Deltaproteobacteria,2MHKW@213118|Desulfobacterales	28221|Deltaproteobacteria	T	PFAM GGDEF domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Response_reg
k59_236769_1	335543.Sfum_1927	2.03e-25	105.0	2AR2D@1|root,31GBD@2|Bacteria,1QE32@1224|Proteobacteria,432R1@68525|delta/epsilon subdivisions,2WXPH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4412)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4412
k59_54841_1	96561.Dole_2308	1.34e-23	91.3	COG1837@1|root,COG1837@2|Bacteria,1N7IX@1224|Proteobacteria,42TXI@68525|delta/epsilon subdivisions,2WQBS@28221|Deltaproteobacteria,2MKI6@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Belongs to the UPF0109 family	-	-	-	ko:K06960	-	-	-	-	ko00000	-	-	-	KH_4
k59_54841_2	1232437.KL662040_gene2135	9.88e-43	143.0	COG1359@1|root,COG1359@2|Bacteria,1NGPW@1224|Proteobacteria,42TXG@68525|delta/epsilon subdivisions,2WQI4@28221|Deltaproteobacteria,2MKN6@213118|Desulfobacterales	28221|Deltaproteobacteria	S	PFAM Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	ABM
k59_199469_2	398767.Glov_2971	8.78e-20	85.1	COG3431@1|root,COG3431@2|Bacteria,1RJWK@1224|Proteobacteria,42T41@68525|delta/epsilon subdivisions,2WRXT@28221|Deltaproteobacteria,43VCW@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Phosphate-starvation-inducible E	-	-	-	-	-	-	-	-	-	-	-	-	PsiE
k59_2188_1	1116472.MGMO_9c00370	7.72e-32	128.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1XDYH@135618|Methylococcales	135618|Methylococcales	T	Diguanylate cyclase phosphodiesterase with PAS PAC	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_9
k59_115802_2	56780.SYN_00426	2.82e-37	137.0	COG0015@1|root,COG0015@2|Bacteria,1MV4B@1224|Proteobacteria,42MYS@68525|delta/epsilon subdivisions,2WJ2E@28221|Deltaproteobacteria,2MREF@213462|Syntrophobacterales	28221|Deltaproteobacteria	F	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	purB	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ADSL_C,Lyase_1
k59_47840_1	335543.Sfum_4058	2.23e-29	115.0	COG0123@1|root,COG0123@2|Bacteria,1MU7P@1224|Proteobacteria,42MY3@68525|delta/epsilon subdivisions,2WJEF@28221|Deltaproteobacteria,2MQYA@213462|Syntrophobacterales	28221|Deltaproteobacteria	BQ	Histone deacetylase domain	-	-	-	ko:K04768	-	-	-	-	ko00000	-	-	-	Hist_deacetyl
k59_47840_2	1033802.SSPSH_000037	3.26e-06	50.4	COG0820@1|root,COG0820@2|Bacteria,1MUYK@1224|Proteobacteria,1RMUI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	GO:0000049,GO:0000154,GO:0001510,GO:0002935,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016426,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0070040,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0140098,GO:0140101,GO:0140102,GO:1901360,GO:1901363	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Radical_SAM
k59_100913_2	335541.Swol_1310	3.13e-12	73.6	COG4373@1|root,COG4373@2|Bacteria,1TQNK@1239|Firmicutes,248R1@186801|Clostridia	186801|Clostridia	S	Mu-like prophage FluMu protein gp28	-	-	-	-	-	-	-	-	-	-	-	-	Terminase_6,Terminase_6C
k59_161636_1	458639.A7KUP5_9CAUD	6.9e-17	89.7	4QECS@10239|Viruses,4QXZ5@35237|dsDNA viruses  no RNA stage	10239|Viruses	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_108353_1	880072.Desac_0427	1.01e-28	119.0	COG0784@1|root,COG1719@1|root,COG4191@1|root,COG0784@2|Bacteria,COG1719@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MC4@68525|delta/epsilon subdivisions,2WIZU@28221|Deltaproteobacteria,2MRI2@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	Signal transduction response regulator, receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_4,PAS_9,Response_reg,dCache_1
k59_47848_1	1408422.JHYF01000003_gene776	3.17e-56	189.0	COG2199@1|root,COG2199@2|Bacteria,1V04Z@1239|Firmicutes,24A7E@186801|Clostridia,36F6P@31979|Clostridiaceae	186801|Clostridia	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
k59_55528_1	760142.Hipma_1089	3.4e-45	178.0	COG3419@1|root,COG3419@2|Bacteria,1NUAV@1224|Proteobacteria,42NJ7@68525|delta/epsilon subdivisions,2WJYB@28221|Deltaproteobacteria,2M6SS@213113|Desulfurellales	28221|Deltaproteobacteria	NU	Tfp pilus assembly protein tip-associated adhesin	-	-	-	ko:K02674	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	Neisseria_PilC
k59_199498_1	1131462.DCF50_p1117	1.5e-05	52.8	COG0535@1|root,COG0535@2|Bacteria,1VD39@1239|Firmicutes,259SB@186801|Clostridia,263IT@186807|Peptococcaceae	186801|Clostridia	C	4Fe-4S single cluster domain	-	-	-	ko:K22227	-	-	-	-	ko00000	-	-	-	Fer4_14,Radical_SAM
k59_123725_1	215803.DB30_2216	4.65e-60	202.0	COG1215@1|root,COG1215@2|Bacteria,1MX08@1224|Proteobacteria,42MS6@68525|delta/epsilon subdivisions,2WIYE@28221|Deltaproteobacteria,2YUMA@29|Myxococcales	28221|Deltaproteobacteria	M	Glycosyl transferase family 21	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3
k59_25044_1	644282.Deba_2882	2.87e-46	155.0	COG1309@1|root,COG1309@2|Bacteria,1MV2V@1224|Proteobacteria,42NW6@68525|delta/epsilon subdivisions,2WPIG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	PFAM regulatory protein TetR	-	-	-	ko:K13770	-	-	-	-	ko00000,ko03000	-	-	-	TetR_C_4,TetR_N
k59_25044_2	644282.Deba_2883	4.27e-17	78.2	COG2086@1|root,COG2086@2|Bacteria,1MVH6@1224|Proteobacteria,42RCI@68525|delta/epsilon subdivisions,2WMYC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Electron transfer flavoprotein	etfB	-	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
k59_2198_1	1121405.dsmv_0229	3.21e-61	201.0	COG0019@1|root,COG0019@2|Bacteria,1R96G@1224|Proteobacteria,42P87@68525|delta/epsilon subdivisions,2WJD9@28221|Deltaproteobacteria,2MJ7I@213118|Desulfobacterales	28221|Deltaproteobacteria	E	PFAM Orn DAP Arg decarboxylase 2	-	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
k59_17257_1	663610.JQKO01000016_gene1629	3.54e-33	126.0	COG3677@1|root,COG3677@2|Bacteria,1MXYX@1224|Proteobacteria,2TQR3@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS1595,Zn_Tnp_IS1595
k59_17257_2	211586.SO_0819	2.11e-21	95.1	COG3677@1|root,COG3677@2|Bacteria,1MXYX@1224|Proteobacteria,1SZQR@1236|Gammaproteobacteria,2QEAJ@267890|Shewanellaceae	1236|Gammaproteobacteria	L	Transposase zinc-ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS1595,Zn_Tnp_IS1595
k59_93215_2	1123298.KB904121_gene1917	1.13e-26	115.0	COG0582@1|root,COG0582@2|Bacteria,1UMEE@1239|Firmicutes,4ITVG@91061|Bacilli	91061|Bacilli	L	Putative transposase	-	-	-	-	-	-	-	-	-	-	-	-	Y2_Tnp
k59_214467_1	177437.HRM2_13550	1.18e-06	48.9	COG0560@1|root,COG0560@2|Bacteria,1MZPG@1224|Proteobacteria,42Q82@68525|delta/epsilon subdivisions,2WMBU@28221|Deltaproteobacteria,2MI8W@213118|Desulfobacterales	28221|Deltaproteobacteria	E	phosphoserine phosphatase homoserine phosphotransferase bifunctional protein	-	-	2.7.1.39,3.1.3.3	ko:K02203	ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00680,map01100,map01110,map01120,map01130,map01230	M00018	R00582,R01771	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HAD
k59_214467_2	1121405.dsmv_3244	1.01e-58	196.0	COG0460@1|root,COG0460@2|Bacteria,1MUDC@1224|Proteobacteria,42MGS@68525|delta/epsilon subdivisions,2WJ1K@28221|Deltaproteobacteria,2MINV@213118|Desulfobacterales	28221|Deltaproteobacteria	E	PFAM homoserine dehydrogenase	hom	-	1.1.1.3	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00017,M00018	R01773,R01775	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,Homoserine_dh,NAD_binding_3
k59_32609_1	1121451.DESAM_22068	5.85e-23	95.5	COG0834@1|root,COG0834@2|Bacteria,1MWDK@1224|Proteobacteria,42NVT@68525|delta/epsilon subdivisions,2WIRY@28221|Deltaproteobacteria,2M8N0@213115|Desulfovibrionales	28221|Deltaproteobacteria	ET	PFAM Extracellular solute-binding protein, family 3	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
k59_191849_1	756272.Plabr_1364	1.32e-69	224.0	COG3119@1|root,COG3119@2|Bacteria,2J24P@203682|Planctomycetes	203682|Planctomycetes	P	Sulfatase	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
k59_78308_1	1118054.CAGW01000025_gene518	6.96e-94	284.0	COG1794@1|root,COG1794@2|Bacteria,1TR3U@1239|Firmicutes,4HCAN@91061|Bacilli,26S5Y@186822|Paenibacillaceae	91061|Bacilli	M	Belongs to the aspartate glutamate racemases family	racD	-	5.1.1.13	ko:K01779	ko00250,ko01054,map00250,map01054	-	R00491	RC00302	ko00000,ko00001,ko01000	-	-	-	Asp_Glu_race
k59_106364_1	1121439.dsat_0437	1.02e-25	102.0	COG0767@1|root,COG0767@2|Bacteria,1MVPN@1224|Proteobacteria,42MR1@68525|delta/epsilon subdivisions,2WKC9@28221|Deltaproteobacteria,2M8PZ@213115|Desulfovibrionales	28221|Deltaproteobacteria	Q	Permease MlaE	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
k59_106364_2	1158345.JNLL01000001_gene159	9.44e-25	100.0	COG1127@1|root,COG1127@2|Bacteria,2G3XY@200783|Aquificae	200783|Aquificae	Q	ABC transporter	-	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
k59_174551_1	316067.Geob_2698	1.09e-61	206.0	COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,42P7N@68525|delta/epsilon subdivisions,2WJKE@28221|Deltaproteobacteria,43TZJ@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	PFAM peptidase M16 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
k59_144218_1	1121405.dsmv_3773	2.8e-45	166.0	COG0567@1|root,COG0567@2|Bacteria,1MVBF@1224|Proteobacteria,42NY6@68525|delta/epsilon subdivisions,2WJSE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Dehydrogenase E1 component	sucA	-	1.2.4.2	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R00621,R01933,R01940,R03316,R08549	RC00004,RC00027,RC00627,RC02743,RC02833,RC02883	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr
k59_204883_1	1121918.ARWE01000001_gene2682	1.52e-55	197.0	COG0210@1|root,COG0514@1|root,COG0210@2|Bacteria,COG0514@2|Bacteria,1MVGG@1224|Proteobacteria,42MV3@68525|delta/epsilon subdivisions,2WJZB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	ATP-dependent DNA helicase RecQ	-	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,UvrD-helicase,UvrD_C
k59_68477_1	879212.DespoDRAFT_02384	1.66e-52	186.0	COG1450@1|root,COG1450@2|Bacteria,1MUUA@1224|Proteobacteria,42M9I@68525|delta/epsilon subdivisions,2WK1H@28221|Deltaproteobacteria,2MIEH@213118|Desulfobacterales	28221|Deltaproteobacteria	NU	type II and III secretion system protein	gspD	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	Secretin,Secretin_N
k59_189736_1	645991.Sgly_1836	1.71e-43	152.0	COG0600@1|root,COG0600@2|Bacteria,1V3NA@1239|Firmicutes,24G03@186801|Clostridia,261GQ@186807|Peptococcaceae	186801|Clostridia	P	PFAM Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02050	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	BPD_transp_1
k59_227612_1	639282.DEFDS_1851	1.12e-56	194.0	COG0439@1|root,COG0439@2|Bacteria	2|Bacteria	I	biotin carboxylase activity	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_3
k59_113913_1	335543.Sfum_2592	3.49e-105	312.0	COG1077@1|root,COG1077@2|Bacteria,1MUMW@1224|Proteobacteria,42M1J@68525|delta/epsilon subdivisions,2WIQR@28221|Deltaproteobacteria,2MQB1@213462|Syntrophobacterales	28221|Deltaproteobacteria	D	TIGRFAM cell shape determining protein, MreB Mrl family	mreB	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
k59_38090_1	1121405.dsmv_1333	6.28e-90	276.0	COG0277@1|root,COG0277@2|Bacteria,1MU6Y@1224|Proteobacteria,42M0V@68525|delta/epsilon subdivisions,2WIQ1@28221|Deltaproteobacteria,2MHUR@213118|Desulfobacterales	28221|Deltaproteobacteria	C	FAD linked oxidases, C-terminal domain	glcD	-	1.1.3.15	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
k59_166947_1	764299.STRIC_0995	7.65e-06	50.8	COG3910@1|root,COG3910@2|Bacteria,1TSWP@1239|Firmicutes,4HBQT@91061|Bacilli	91061|Bacilli	S	ATPase (AAA	cysA1	-	-	-	-	-	-	-	-	-	-	-	AAA_21,AAA_23
k59_7812_1	1134413.ANNK01000085_gene422	1.77e-12	72.4	COG0697@1|root,COG0697@2|Bacteria,1V0DI@1239|Firmicutes,4HD1I@91061|Bacilli,1ZQ3C@1386|Bacillus	91061|Bacilli	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
k59_121498_1	1037409.BJ6T_20480	4.88e-08	59.3	COG3547@1|root,COG3547@2|Bacteria,1MW0N@1224|Proteobacteria,2TUGE@28211|Alphaproteobacteria,3JX5I@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	L	PFAM transposase IS116 IS110 IS902 family	-	-	-	ko:K07486	-	-	-	-	ko00000	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_235246_1	1232410.KI421421_gene3802	2.09e-32	122.0	COG3762@1|root,COG3762@2|Bacteria,1R61N@1224|Proteobacteria,42QZE@68525|delta/epsilon subdivisions,2WMQH@28221|Deltaproteobacteria,43W06@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Membrane	-	-	-	ko:K08988	-	-	-	-	ko00000	-	-	-	TPM_phosphatase
k59_204902_1	880072.Desac_1215	1.28e-39	148.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MR8@68525|delta/epsilon subdivisions,2WIUA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	histidine kinase HAMP region domain protein	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
k59_38095_1	717774.Marme_2330	9.87e-16	84.3	COG0515@1|root,COG3899@1|root,COG0515@2|Bacteria,COG3899@2|Bacteria,1MV1P@1224|Proteobacteria,1RR36@1236|Gammaproteobacteria,1XR5H@135619|Oceanospirillales	135619|Oceanospirillales	KLT	COG0515 Serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
k59_144235_1	386456.JQKN01000005_gene501	1.35e-26	106.0	COG0655@1|root,arCOG02573@2157|Archaea,2XVMU@28890|Euryarchaeota,23PMW@183925|Methanobacteria	183925|Methanobacteria	S	PFAM NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
k59_30546_1	96561.Dole_3250	7.28e-105	319.0	COG3039@1|root,COG3039@2|Bacteria,1QQ9Q@1224|Proteobacteria,42S7X@68525|delta/epsilon subdivisions,2WNJ2@28221|Deltaproteobacteria,2MJG4@213118|Desulfobacterales	28221|Deltaproteobacteria	L	PFAM transposase IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DUF772
k59_159404_1	335543.Sfum_0808	1.05e-40	146.0	COG0589@1|root,COG0589@2|Bacteria,1REA3@1224|Proteobacteria,42RXY@68525|delta/epsilon subdivisions,2WNM6@28221|Deltaproteobacteria,2MSDJ@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	PFAM UspA domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
k59_204909_1	202752.JL53_14330	1.02e-15	78.6	COG1484@1|root,COG1484@2|Bacteria,1TS3R@1239|Firmicutes,4HDHZ@91061|Bacilli,26KX9@186820|Listeriaceae	91061|Bacilli	L	Pfam PF01695	-	-	-	-	-	-	-	-	-	-	-	-	IstB_IS21
k59_76006_1	1123277.KB893197_gene6105	0.000287	50.1	COG1520@1|root,COG3266@1|root,COG1520@2|Bacteria,COG3266@2|Bacteria,4NQBS@976|Bacteroidetes,47QPM@768503|Cytophagia	976|Bacteroidetes	S	FG-GAP repeat	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP_2
k59_159410_1	1144275.COCOR_01016	8.45e-27	113.0	COG3276@1|root,COG3276@2|Bacteria,1MWXH@1224|Proteobacteria,42M49@68525|delta/epsilon subdivisions,2WJ5G@28221|Deltaproteobacteria,2YU0Y@29|Myxococcales	28221|Deltaproteobacteria	J	Selenocysteine-specific translation elongation factor	selB	-	-	ko:K03833	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,SelB-wing_2,SelB-wing_3
k59_76007_1	717231.Flexsi_0999	2.61e-11	64.7	COG0328@1|root,COG0328@2|Bacteria,2GFX8@200930|Deferribacteres	200930|Deferribacteres	L	Reverse transcriptase-like	-	-	3.1.26.4	ko:K03469	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RVT_3
k59_121503_1	398767.Glov_3440	5.48e-52	184.0	COG2199@1|root,COG2199@2|Bacteria,1RGCV@1224|Proteobacteria,42SQY@68525|delta/epsilon subdivisions,2X7WY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
k59_159414_1	1304888.ATWF01000001_gene2042	6.02e-10	60.5	COG0489@1|root,COG0489@2|Bacteria,2GEUR@200930|Deferribacteres	200930|Deferribacteres	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	-	-	-	-	-	-	-	-	-	-	-	-	ParA
k59_159414_2	177437.HRM2_42460	1.2e-38	132.0	COG1433@1|root,COG1433@2|Bacteria,1MZ77@1224|Proteobacteria,42U3G@68525|delta/epsilon subdivisions,2WQ5N@28221|Deltaproteobacteria,2MKGB@213118|Desulfobacterales	28221|Deltaproteobacteria	S	PFAM Dinitrogenase iron-molybdenum cofactor	-	-	-	-	-	-	-	-	-	-	-	-	Nitro_FeMo-Co
k59_220119_1	56780.SYN_02534	3.92e-87	271.0	COG0124@1|root,COG0124@2|Bacteria,1MV2K@1224|Proteobacteria,42MG0@68525|delta/epsilon subdivisions,2WJE1@28221|Deltaproteobacteria,2MQBI@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	tRNA synthetase class II core domain (G, H, P, S and T)	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
k59_235255_1	575540.Isop_0433	4.82e-07	57.8	COG0568@1|root,COG0568@2|Bacteria,2IY72@203682|Planctomycetes	203682|Planctomycetes	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03086,ko:K03093	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4
k59_189759_2	335543.Sfum_1278	4.72e-84	267.0	COG0427@1|root,COG0454@1|root,COG0427@2|Bacteria,COG0456@2|Bacteria,1MUGE@1224|Proteobacteria,42MHC@68525|delta/epsilon subdivisions,2WINZ@28221|Deltaproteobacteria,2MR2F@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	acetyl-CoA	-	-	-	ko:K18122,ko:K18288	ko00650,ko00660,ko01100,ko01200,map00650,map00660,map01100,map01200	-	R02407,R05336,R10600	RC00012,RC00014	ko00000,ko00001,ko01000	-	-	iAF987.Gmet_2142,iAF987.Gmet_3304	AcetylCoA_hyd_C,AcetylCoA_hydro,Acetyltransf_1,Acetyltransf_3
k59_214_1	296591.Bpro_3741	4.91e-93	292.0	COG4386@1|root,COG4386@2|Bacteria,1MXZD@1224|Proteobacteria,2VKVD@28216|Betaproteobacteria,4AH5R@80864|Comamonadaceae	28216|Betaproteobacteria	S	Phage tail sheath C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Phage_sheath_1,Phage_sheath_1C
k59_53264_1	868131.MSWAN_1777	1.3e-49	176.0	COG1032@1|root,arCOG01356@2157|Archaea,2XU04@28890|Euryarchaeota	28890|Euryarchaeota	C	SMART Elongator protein 3 MiaB NifB	-	-	1.21.98.3	ko:K04034	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R06268,R06269,R06270	RC00741,RC01491,RC01492	ko00000,ko00001,ko01000	-	-	-	B12-binding,Radical_SAM
k59_151860_1	706587.Desti_5497	4.07e-22	96.7	COG0407@1|root,COG0407@2|Bacteria,1R9IN@1224|Proteobacteria,42Q1Q@68525|delta/epsilon subdivisions,2WMDE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	PFAM Uroporphyrinogen decarboxylase (URO-D)	-	-	-	-	-	-	-	-	-	-	-	-	URO-D
k59_15360_1	56780.SYN_00415	4.01e-34	130.0	COG0795@1|root,COG0795@2|Bacteria,1MVW3@1224|Proteobacteria,42N5X@68525|delta/epsilon subdivisions,2WJ3H@28221|Deltaproteobacteria,2MQIX@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Permease YjgP YjgQ family	lptG	-	-	ko:K11720	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
k59_227640_1	370438.PTH_2616	9.11e-119	362.0	COG0303@1|root,COG1910@1|root,COG0303@2|Bacteria,COG1910@2|Bacteria,1TRH3@1239|Firmicutes,24ATZ@186801|Clostridia,2612F@186807|Peptococcaceae	186801|Clostridia	HP	TIGRFAM molybdenum cofactor synthesis	-	-	2.10.1.1	ko:K03750,ko:K07219	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N,PBP_like
k59_121523_2	1232437.KL662026_gene988	1.67e-40	145.0	COG0674@1|root,COG0674@2|Bacteria,1MVM0@1224|Proteobacteria,42MZ0@68525|delta/epsilon subdivisions,2WJG3@28221|Deltaproteobacteria,2MJ3H@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Pyruvate:ferredoxin oxidoreductase core domain II	-	-	1.2.7.1	ko:K00169	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR_N
k59_227648_1	768671.ThimaDRAFT_0087	3.02e-49	169.0	COG0628@1|root,COG0628@2|Bacteria,1MXXU@1224|Proteobacteria,1RQCM@1236|Gammaproteobacteria,1WXT8@135613|Chromatiales	135613|Chromatiales	S	PFAM Uncharacterised protein family UPF0118	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
k59_227654_1	1121405.dsmv_1871	1.16e-32	117.0	2CM87@1|root,32SDZ@2|Bacteria,1N0M3@1224|Proteobacteria,42UHD@68525|delta/epsilon subdivisions,2WQ5V@28221|Deltaproteobacteria,2MKHI@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_136694_1	1287276.X752_00825	5.06e-35	134.0	COG0404@1|root,COG0404@2|Bacteria,1R3WG@1224|Proteobacteria,2U0M4@28211|Alphaproteobacteria,43HEW@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	E	Belongs to the GcvT family	-	-	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
k59_30586_1	1121447.JONL01000001_gene728	1e-27	105.0	COG0244@1|root,COG0244@2|Bacteria,1RAN5@1224|Proteobacteria,42R1J@68525|delta/epsilon subdivisions,2WQE8@28221|Deltaproteobacteria,2MG76@213115|Desulfovibrionales	28221|Deltaproteobacteria	J	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors	rplJ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02864	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L10
k59_30586_2	1121405.dsmv_3646	6.3e-38	130.0	COG0222@1|root,COG0222@2|Bacteria,1RGU4@1224|Proteobacteria,42SHZ@68525|delta/epsilon subdivisions,2WPFZ@28221|Deltaproteobacteria,2MK53@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation	rplL	-	-	ko:K02935	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L12,Ribosomal_L12_N
k59_91175_1	1144319.PMI16_04366	4.57e-23	96.7	COG4312@1|root,COG4312@2|Bacteria,1NAXN@1224|Proteobacteria,2VK34@28216|Betaproteobacteria,476AW@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Bacterial protein of unknown function (DUF899)	-	-	-	-	-	-	-	-	-	-	-	-	DUF899
k59_227667_1	933262.AXAM01000081_gene2257	1.42e-91	287.0	COG1080@1|root,COG1080@2|Bacteria,1MUT8@1224|Proteobacteria,42P77@68525|delta/epsilon subdivisions,2WK7E@28221|Deltaproteobacteria,2MIQB@213118|Desulfobacterales	28221|Deltaproteobacteria	G	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)	ptsI	-	2.7.3.9	ko:K08483	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	8.A.7	-	-	PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C
k59_68504_1	225849.swp_0808	4.93e-07	58.2	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,2Q98T@267890|Shewanellaceae	1236|Gammaproteobacteria	NT	PFAM histidine kinase, HAMP region domain protein	tlpA	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal,dCache_1
k59_227673_2	291112.PAU_02999	1.35e-21	97.4	COG4974@1|root,COG4974@2|Bacteria,1MVNF@1224|Proteobacteria,1S1T0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	integrase recombinase protein rsp0090 or rs05531 SWALL Q8XTL6 (EMBL AL646076) (347 aa) fasta scores E()	-	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_int_SAM_4,Phage_integrase
k59_7841_1	665942.HMPREF1022_03100	9.83e-16	70.9	COG1146@1|root,COG1146@2|Bacteria,1QWQ4@1224|Proteobacteria,43BUY@68525|delta/epsilon subdivisions,2X75X@28221|Deltaproteobacteria,2MHB0@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_7
k59_151897_1	933262.AXAM01000016_gene187	8.05e-50	171.0	28V7D@1|root,2ZHAI@2|Bacteria,1RA29@1224|Proteobacteria,42R9H@68525|delta/epsilon subdivisions,2WN1D@28221|Deltaproteobacteria,2MJN2@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4340)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4340
k59_204972_2	1316927.ATKI01000034_gene4590	2.23e-110	332.0	28H52@1|root,2Z7HQ@2|Bacteria,1MXTF@1224|Proteobacteria,1T9GG@1236|Gammaproteobacteria,1YSMK@136843|Pseudomonas fluorescens group	1236|Gammaproteobacteria	S	Protein of unknown function (DUF1329)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1329
k59_53304_1	1125699.HMPREF9194_01341	3.06e-38	139.0	COG1253@1|root,COG1253@2|Bacteria,2J61P@203691|Spirochaetes	203691|Spirochaetes	S	COGs COG1253 Hemolysins and related protein containing CBS domains	tlyC	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC
k59_68520_1	243090.RB12862	2.08e-37	147.0	COG4166@1|root,COG4166@2|Bacteria,2IY5J@203682|Planctomycetes	203682|Planctomycetes	E	Bacterial extracellular solute-binding proteins, family 5 Middle	oppA	-	-	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	SBP_bac_5
k59_91660_2	1232437.KL662006_gene4387	9.52e-36	124.0	COG2208@1|root,COG2208@2|Bacteria	2|Bacteria	T	phosphoserine phosphatase activity	pkn5	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	AAA_16,GAF,HAMP,Pkinase,Response_reg,SpoIIE,dCache_1
k59_106904_1	404589.Anae109_2545	2.94e-16	79.3	COG0568@1|root,COG0568@2|Bacteria,1MVWR@1224|Proteobacteria,42NRM@68525|delta/epsilon subdivisions,2WJ0S@28221|Deltaproteobacteria,2YU1B@29|Myxococcales	28221|Deltaproteobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	rpoH	-	-	ko:K03086,ko:K03089	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
k59_15882_1	1123376.AUIU01000004_gene1166	4.11e-70	225.0	COG1004@1|root,COG1004@2|Bacteria,3J0EJ@40117|Nitrospirae	40117|Nitrospirae	C	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	-	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
k59_167446_1	667014.Thein_0302	2.14e-89	278.0	COG0119@1|root,COG0119@2|Bacteria,2GGR2@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	E	Belongs to the alpha-IPM synthase homocitrate synthase family	-	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
k59_46223_1	177437.HRM2_03790	1.37e-100	306.0	COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,42MEA@68525|delta/epsilon subdivisions,2WIW6@28221|Deltaproteobacteria,2MI74@213118|Desulfobacterales	28221|Deltaproteobacteria	KT	Sigma-54 interaction domain	-	-	2.1.1.80	ko:K00575	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	HTH_8,PAS_4,PAS_9,Sigma54_activat
k59_235813_1	945713.IALB_1964	6.27e-31	122.0	COG0166@1|root,COG0176@1|root,COG0166@2|Bacteria,COG0176@2|Bacteria	2|Bacteria	G	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	tal	-	1.1.1.343,1.1.1.44,2.2.1.2,3.1.26.12,5.3.1.9	ko:K00033,ko:K00616,ko:K01810,ko:K08300,ko:K13810	ko00010,ko00030,ko00480,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,map00010,map00030,map00480,map00500,map00520,map01100,map01110,map01120,map01130,map01200,map01230,map03018	M00001,M00004,M00006,M00007,M00114,M00394	R01528,R01827,R02739,R02740,R03321,R10221	RC00001,RC00376,RC00439,RC00539,RC00563,RC00604	ko00000,ko00001,ko00002,ko01000,ko03009,ko03019,ko04147	-	-	-	PGI,TAL_FSA
k59_205533_1	56780.SYN_03249	2.52e-98	299.0	COG3464@1|root,COG3464@2|Bacteria,1N2V1@1224|Proteobacteria,42TEG@68525|delta/epsilon subdivisions,2WPXW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	Helix-turn-helix domain of transposase family ISL3	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3
k59_137270_1	1318628.MARLIPOL_05784	2.83e-12	68.6	COG0204@1|root,COG0204@2|Bacteria,1MY51@1224|Proteobacteria,1SB50@1236|Gammaproteobacteria,467EZ@72275|Alteromonadaceae	1236|Gammaproteobacteria	I	COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
k59_129625_1	335543.Sfum_0247	1.99e-50	172.0	COG3698@1|root,COG3698@2|Bacteria,1RCEZ@1224|Proteobacteria,437YQ@68525|delta/epsilon subdivisions,2X38M@28221|Deltaproteobacteria,2MSEB@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Phosphodiester glycosidase	-	-	-	-	-	-	-	-	-	-	-	-	NAGPA
k59_8352_1	1476876.JOJO01000033_gene3948	6.08e-06	52.8	COG0500@1|root,COG1051@1|root,COG1051@2|Bacteria,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25,NUDIX
k59_23530_1	98439.AJLL01000014_gene1638	3.66e-44	154.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
k59_8353_1	335543.Sfum_0009	1.22e-69	221.0	COG0505@1|root,COG0505@2|Bacteria,1MUB9@1224|Proteobacteria,42KZG@68525|delta/epsilon subdivisions,2WIQ5@28221|Deltaproteobacteria,2MRH5@213462|Syntrophobacterales	28221|Deltaproteobacteria	F	Carbamoyl-phosphate synthase small chain, CPSase domain	carA	-	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_sm_chain,GATase
k59_197896_1	913865.DOT_1227	4.23e-56	178.0	COG1765@1|root,COG1765@2|Bacteria,1V7SN@1239|Firmicutes,24SS3@186801|Clostridia	186801|Clostridia	O	redox protein, regulator of disulfide bond	-	-	-	ko:K07397	-	-	-	-	ko00000	-	-	-	OsmC
k59_76636_1	177439.DP0288	3.66e-81	255.0	COG0659@1|root,COG0659@2|Bacteria,1MX1U@1224|Proteobacteria,42Q8Y@68525|delta/epsilon subdivisions,2WK07@28221|Deltaproteobacteria,2MJB0@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Molybdate transporter of MFS superfamily	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	MFS_MOT1
k59_228102_2	247634.GPB2148_1961	3.85e-56	191.0	COG1524@1|root,COG1524@2|Bacteria,1R5V5@1224|Proteobacteria,1S06C@1236|Gammaproteobacteria,1J9AQ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	proteins of the AP superfamily	pafA	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
k59_106926_1	368407.Memar_2179	2.47e-34	123.0	COG1793@1|root,arCOG05256@2157|Archaea,2XY7Z@28890|Euryarchaeota,2N9V7@224756|Methanomicrobia	224756|Methanomicrobia	L	DNA polymerase Ligase (LigD)	-	-	-	-	-	-	-	-	-	-	-	-	LigD_N
k59_15895_1	933262.AXAM01000019_gene1129	8.38e-47	161.0	COG1234@1|root,COG1234@2|Bacteria,1PE64@1224|Proteobacteria,42RZR@68525|delta/epsilon subdivisions,2WMCC@28221|Deltaproteobacteria,2MIZZ@213118|Desulfobacterales	28221|Deltaproteobacteria	S	beta-lactamase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
k59_31072_1	1232437.KL661976_gene4973	5.99e-81	253.0	COG5557@1|root,COG5557@2|Bacteria,1MWYI@1224|Proteobacteria,42PH3@68525|delta/epsilon subdivisions,2WJZH@28221|Deltaproteobacteria,2MIN0@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Polysulphide reductase, NrfD	-	-	-	-	-	-	-	-	-	-	-	-	NrfD
k59_23539_2	207559.Dde_1175	1.63e-23	92.4	COG0724@1|root,COG0724@2|Bacteria,1N6VR@1224|Proteobacteria,42UQP@68525|delta/epsilon subdivisions,2WQKU@28221|Deltaproteobacteria,2MGUH@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	PFAM RNA recognition motif	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
k59_132314_1	387631.Asulf_00014	9.76e-43	144.0	COG1142@1|root,arCOG01502@2157|Archaea,2XXP9@28890|Euryarchaeota,247D4@183980|Archaeoglobi	183980|Archaeoglobi	C	4Fe-4S dicluster domain	-	-	-	ko:K00196	ko00633,ko00680,ko00720,ko01120,ko01200,map00633,map00680,map00720,map01120,map01200	-	R07157,R08034	RC00250,RC02800	ko00000,ko00001	-	-	-	Fer4_11
k59_94308_1	1313172.YM304_35010	7.3e-40	149.0	COG1529@1|root,COG2080@1|root,COG1529@2|Bacteria,COG2080@2|Bacteria,2GIY7@201174|Actinobacteria	201174|Actinobacteria	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	iorB	-	1.3.99.16	ko:K07303	-	-	-	-	ko00000,ko01000	-	-	-	Ald_Xan_dh_C2
k59_79343_1	1121413.JMKT01000009_gene2136	2.07e-108	330.0	COG0519@1|root,COG0519@2|Bacteria,1MU2A@1224|Proteobacteria,42M0I@68525|delta/epsilon subdivisions,2WJ6D@28221|Deltaproteobacteria,2M88N@213115|Desulfovibrionales	28221|Deltaproteobacteria	F	Catalyzes the synthesis of GMP from XMP	guaA	GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase,tRNA_Me_trans
k59_11085_1	1121405.dsmv_1080	1.79e-58	187.0	COG0755@1|root,COG0755@2|Bacteria,1RG6M@1224|Proteobacteria,43BH8@68525|delta/epsilon subdivisions,2X6VM@28221|Deltaproteobacteria,2MPIN@213118|Desulfobacterales	28221|Deltaproteobacteria	O	TIGRFAM cytochrome c-type biogenesis protein CcsB	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm
k59_11085_2	1121405.dsmv_1079	7.8e-29	110.0	COG3474@1|root,COG3474@2|Bacteria,1QUNA@1224|Proteobacteria,42PVG@68525|delta/epsilon subdivisions,2WJ7N@28221|Deltaproteobacteria,2MIQK@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Cytochrome c7 and related cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_CIII,Cytochrome_C7
k59_155220_1	368408.Tpen_0908	1.75e-91	278.0	COG0489@1|root,arCOG00585@2157|Archaea,2XPV2@28889|Crenarchaeota	28889|Crenarchaeota	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	-	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	ParA
k59_132327_1	909663.KI867150_gene718	8.3e-28	112.0	COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,42M9N@68525|delta/epsilon subdivisions,2WIZR@28221|Deltaproteobacteria,2MRAN@213462|Syntrophobacterales	28221|Deltaproteobacteria	G	Tripartite ATP-independent periplasmic transporter, DctM component	-	-	-	-	-	-	-	-	-	-	-	-	DctM
k59_162534_2	1121405.dsmv_3735	2.83e-180	509.0	COG0183@1|root,COG0183@2|Bacteria,1MUZV@1224|Proteobacteria,43AZR@68525|delta/epsilon subdivisions,2X6DY@28221|Deltaproteobacteria,2MPHW@213118|Desulfobacterales	28221|Deltaproteobacteria	I	Thiolase, C-terminal domain	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
k59_18314_1	439235.Dalk_0495	4.97e-45	165.0	COG0515@1|root,COG0515@2|Bacteria,1R8C8@1224|Proteobacteria,42Q9Y@68525|delta/epsilon subdivisions,2WME3@28221|Deltaproteobacteria,2MJ3C@213118|Desulfobacterales	28221|Deltaproteobacteria	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
k59_33695_1	335543.Sfum_3724	2.26e-51	182.0	COG0077@1|root,COG2876@1|root,COG0077@2|Bacteria,COG2876@2|Bacteria,1QVAD@1224|Proteobacteria,42MU4@68525|delta/epsilon subdivisions,2WJ8Y@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	PFAM DAHP synthetase I KDSA	-	-	2.5.1.54,5.4.99.5	ko:K03856,ko:K04516	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022,M00024,M00025	R01715,R01826	RC00435,RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,CM_2,DAHP_synth_1,PDT
k59_125025_2	221988.MS1934	0.000759	44.3	COG0664@1|root,COG0664@2|Bacteria,1MXID@1224|Proteobacteria,1RMIZ@1236|Gammaproteobacteria,1Y7GC@135625|Pasteurellales	135625|Pasteurellales	K	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases	crp	-	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	Crp,cNMP_binding
k59_132337_1	1408473.JHXO01000009_gene3319	1.31e-63	203.0	COG1489@1|root,COG1489@2|Bacteria,4NKJC@976|Bacteroidetes,2FWK1@200643|Bacteroidia	976|Bacteroidetes	S	Sugar fermentation stimulation protein	sfsA	-	-	ko:K06206	-	-	-	-	ko00000	-	-	-	SfsA
k59_200503_1	1121403.AUCV01000043_gene96	1.09e-88	275.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42ME4@68525|delta/epsilon subdivisions,2WJA5@28221|Deltaproteobacteria,2MIGA@213118|Desulfobacterales	28221|Deltaproteobacteria	T	CheY-like receiver, AAA-type ATPase, and DNA-binding	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
k59_140009_1	1121396.KB892913_gene116	2.98e-56	190.0	COG0517@1|root,COG0517@2|Bacteria,1MXI6@1224|Proteobacteria,42WI2@68525|delta/epsilon subdivisions,2WRPD@28221|Deltaproteobacteria,2MQ18@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Transposase zinc-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Y2_Tnp,Zn_Tnp_IS91
k59_140009_2	331678.Cphamn1_1145	4.96e-32	130.0	COG4974@1|root,COG4974@2|Bacteria	2|Bacteria	L	Belongs to the 'phage' integrase family	int	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_4,Phage_integrase
k59_238346_1	1265505.ATUG01000001_gene4046	1.99e-59	207.0	COG0642@1|root,COG4191@1|root,COG2205@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MC4@68525|delta/epsilon subdivisions,2WIU5@28221|Deltaproteobacteria,2MIV8@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS_9,Response_reg
k59_102177_1	439235.Dalk_3639	5.44e-11	62.0	COG2759@1|root,COG2759@2|Bacteria,1MUR8@1224|Proteobacteria,42MKE@68525|delta/epsilon subdivisions,2WJF1@28221|Deltaproteobacteria,2MJ0Z@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Belongs to the formate--tetrahydrofolate ligase family	fhs	-	6.3.4.3	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R00943	RC00026,RC00111	ko00000,ko00001,ko00002,ko01000	-	-	-	FTHFS
k59_86575_1	883.DvMF_1001	1.31e-51	177.0	COG0502@1|root,COG0502@2|Bacteria,1MVFF@1224|Proteobacteria,42NGR@68525|delta/epsilon subdivisions,2WIMA@28221|Deltaproteobacteria,2M83D@213115|Desulfovibrionales	28221|Deltaproteobacteria	H	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism	bioB	-	2.8.1.6,5.4.99.58	ko:K01012,ko:K16180	ko00300,ko00780,ko01100,ko01120,map00300,map00780,map01100,map01120	M00123,M00573,M00577	R01078,R10010	RC00441,RC02995	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1582	BATS,Radical_SAM
k59_132342_1	523845.AQXV01000034_gene393	1.56e-37	141.0	COG1498@1|root,arCOG01923@2157|Archaea,2XUEA@28890|Euryarchaeota,23Q08@183939|Methanococci	183939|Methanococci	J	PFAM Pre-mRNA processing ribonucleoprotein, binding	-	GO:0000154,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0030515,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363	-	ko:K14564	ko03008,map03008	-	-	-	ko00000,ko00001,ko03009	-	-	-	Nop
k59_41209_1	1121403.AUCV01000001_gene996	6.58e-93	283.0	28IVT@1|root,2Z8U5@2|Bacteria,1R7G9@1224|Proteobacteria,42Z49@68525|delta/epsilon subdivisions,2WUQH@28221|Deltaproteobacteria,2MMWP@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_79360_1	1265505.ATUG01000002_gene1275	1.63e-40	139.0	COG5319@1|root,COG5319@2|Bacteria,1MZN2@1224|Proteobacteria,42SXV@68525|delta/epsilon subdivisions,2WPSN@28221|Deltaproteobacteria,2MK91@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF1178)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1178
k59_125032_1	56780.SYN_01406	1.69e-43	145.0	COG1950@1|root,COG1950@2|Bacteria,1N1DF@1224|Proteobacteria,42WCF@68525|delta/epsilon subdivisions,2WRES@28221|Deltaproteobacteria,2MQP9@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Mycobacterial 4 TMS phage holin, superfamily IV	-	-	-	ko:K08972	-	-	-	-	ko00000	-	-	-	Phage_holin_4_2
k59_33710_1	706587.Desti_2540	1.26e-83	256.0	COG1013@1|root,COG1013@2|Bacteria,1MUY9@1224|Proteobacteria,42MQY@68525|delta/epsilon subdivisions,2WJGJ@28221|Deltaproteobacteria,2MREB@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	PFAM thiamine pyrophosphate enzyme	-	-	1.2.7.1	ko:K00170	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
k59_71565_1	1380386.JIAW01000026_gene6947	4.1e-15	76.6	28HT7@1|root,2Z804@2|Bacteria,2H3RB@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_79366_1	525897.Dbac_0679	1.34e-20	99.8	COG4783@1|root,COG4783@2|Bacteria,1MVFV@1224|Proteobacteria,42MBR@68525|delta/epsilon subdivisions,2WJ0Z@28221|Deltaproteobacteria,2M953@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	PFAM peptidase M48 Ste24p	-	-	-	-	-	-	-	-	-	-	-	iAF987.Gmet_1238	Peptidase_M48,TPR_14,TPR_16,TPR_19
k59_48735_1	1536769.P40081_14940	2.5e-05	50.8	COG1479@1|root,COG1479@2|Bacteria,1UFEC@1239|Firmicutes,4IF6U@91061|Bacilli,270R9@186822|Paenibacillaceae	91061|Bacilli	S	Protein of unknown function DUF262	-	-	-	-	-	-	-	-	-	-	-	-	DUF262
k59_140022_1	1123070.KB899257_gene2298	7.73e-07	52.8	COG0810@1|root,COG0810@2|Bacteria,46WNS@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Gram-negative bacterial TonB protein C-terminal	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
k59_11116_1	671143.DAMO_1528	3.01e-80	252.0	COG3004@1|root,COG3004@2|Bacteria,2NNWA@2323|unclassified Bacteria	2|Bacteria	P	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons	nhaA	-	-	ko:K03313	-	-	-	-	ko00000,ko02000	2.A.33.1	-	-	Na_H_antiport_1
k59_155248_1	592316.Pat9b_1945	1.17e-15	82.0	COG0665@1|root,COG0665@2|Bacteria,1MU7M@1224|Proteobacteria,1RP7W@1236|Gammaproteobacteria,3VZAF@53335|Pantoea	1236|Gammaproteobacteria	E	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
k59_11117_1	933262.AXAM01000005_gene2516	4.36e-47	162.0	COG1868@1|root,COG1868@2|Bacteria,1MX01@1224|Proteobacteria,42N2Y@68525|delta/epsilon subdivisions,2WIS2@28221|Deltaproteobacteria,2MI59@213118|Desulfobacterales	28221|Deltaproteobacteria	N	flagellar motor switch protein FliM	fliM	-	-	ko:K02416	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliM,FliMN_C
k59_56630_1	1219065.VPR01S_07_00400	6.71e-16	82.8	COG0845@1|root,COG0845@2|Bacteria,1MU78@1224|Proteobacteria,1RMI7@1236|Gammaproteobacteria,1Y2IY@135623|Vibrionales	135623|Vibrionales	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
k59_117240_2	335543.Sfum_1977	1.42e-30	123.0	COG1148@1|root,COG1148@2|Bacteria,1QUM4@1224|Proteobacteria,42MPP@68525|delta/epsilon subdivisions,2WJ3U@28221|Deltaproteobacteria,2MQTI@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_4,Fer4_7,Pyr_redox_2
k59_72274_2	335543.Sfum_0318	8.27e-102	299.0	COG1100@1|root,COG1100@2|Bacteria,1R6NS@1224|Proteobacteria,42NIX@68525|delta/epsilon subdivisions,2WJ44@28221|Deltaproteobacteria,2MRJG@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	ADP-ribosylation factor family	mglA	GO:0008150,GO:0032879,GO:0032880,GO:0050789,GO:0065007	-	ko:K06883	-	-	-	-	ko00000	-	-	-	Arf,Ras
k59_238678_1	880072.Desac_0013	2.2e-73	230.0	COG0535@1|root,COG0535@2|Bacteria,1MUQP@1224|Proteobacteria,42N9E@68525|delta/epsilon subdivisions,2WJAX@28221|Deltaproteobacteria,2MQ7H@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	PFAM Radical SAM	-	-	-	ko:K22226	-	-	-	-	ko00000	-	-	-	Fer4_12,Radical_SAM,SPASM
k59_231669_1	909663.KI867150_gene87	2.95e-27	110.0	COG4585@1|root,COG4585@2|Bacteria,1MWPN@1224|Proteobacteria,42RUN@68525|delta/epsilon subdivisions,2WNJZ@28221|Deltaproteobacteria,2MR4S@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE4,HAMP,HATPase_c,HisKA_3,PAS_3,PAS_4,PAS_9
k59_231669_2	690850.Desaf_2891	2.52e-52	171.0	COG2197@1|root,COG2197@2|Bacteria,1MWGM@1224|Proteobacteria,42R03@68525|delta/epsilon subdivisions,2WMTZ@28221|Deltaproteobacteria,2MCTY@213115|Desulfovibrionales	28221|Deltaproteobacteria	K	response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
k59_87150_1	439235.Dalk_4966	1.61e-65	223.0	COG1148@1|root,COG1148@2|Bacteria,1QUM4@1224|Proteobacteria,42MPP@68525|delta/epsilon subdivisions,2WJ3U@28221|Deltaproteobacteria,2MJ2D@213118|Desulfobacterales	28221|Deltaproteobacteria	C	FAD binding domain	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_7,Pyr_redox_2
k59_3336_1	198467.NP92_06095	3.38e-61	208.0	COG0464@1|root,COG0464@2|Bacteria,1TQTZ@1239|Firmicutes,4HF00@91061|Bacilli	91061|Bacilli	O	ATPase family associated with various cellular activities (AAA)	-	-	-	-	-	-	-	-	-	-	-	-	AAA
k59_125514_1	497964.CfE428DRAFT_5783	8.87e-70	234.0	COG2304@1|root,COG2304@2|Bacteria,46SHE@74201|Verrucomicrobia	74201|Verrucomicrobia	K	PFAM von Willebrand factor type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	DUF3520,VWA,vWF_A
k59_110123_2	1121448.DGI_2993	6.58e-99	305.0	COG2203@1|root,COG2208@1|root,COG2203@2|Bacteria,COG2208@2|Bacteria,1PFBF@1224|Proteobacteria,42RAR@68525|delta/epsilon subdivisions,2WN52@28221|Deltaproteobacteria,2MAC7@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	Sigma factor PP2C-like phosphatases	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,SpoIIE
k59_186360_1	888833.HMPREF9421_1102	8.32e-50	167.0	COG0274@1|root,COG0274@2|Bacteria,1TPAJ@1239|Firmicutes,4HAAJ@91061|Bacilli	91061|Bacilli	F	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate	deoC	GO:0003674,GO:0003824,GO:0004139,GO:0005975,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009262,GO:0009264,GO:0009987,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576	4.1.2.4	ko:K01619	ko00030,map00030	-	R01066	RC00436,RC00437	ko00000,ko00001,ko01000	-	-	iSB619.SA_RS00835	DeoC
k59_72289_1	285535.JOEY01000016_gene3612	1.38e-63	219.0	COG1404@1|root,COG2931@1|root,COG1404@2|Bacteria,COG2931@2|Bacteria,2GX6F@201174|Actinobacteria	201174|Actinobacteria	Q	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8,Tyrosinase,VCBS
k59_201150_1	207559.Dde_1185	2.46e-119	357.0	COG0747@1|root,COG0747@2|Bacteria,1MUZH@1224|Proteobacteria,42N16@68525|delta/epsilon subdivisions,2X73Y@28221|Deltaproteobacteria,2MBUH@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	Bacterial extracellular solute-binding proteins, family 5 Middle	dppA	-	-	ko:K02035,ko:K12368	ko02010,ko02024,ko02030,map02010,map02024,map02030	M00239,M00324	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
k59_11878_1	10224.XP_006825930.1	1.19e-49	181.0	KOG1075@1|root,KOG1075@2759|Eukaryota,39Y6T@33154|Opisthokonta,3BEGN@33208|Metazoa,3CZ7K@33213|Bilateria	33208|Metazoa	G	positive regulation of TOR signaling	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos_2,RVT_1
k59_177941_1	195105.CN97_17190	1.07e-42	158.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,2TQR1@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	belongs to the aldehyde dehydrogenase family	-	-	1.2.1.16,1.2.1.20,1.2.1.79	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	M00027	R00713,R00714,R02401	RC00080	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
k59_18868_1	574966.KB898649_gene228	4.28e-24	108.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,1XHXU@135619|Oceanospirillales	135619|Oceanospirillales	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_186370_1	247490.KSU1_D0425	0.000116	48.1	COG2199@1|root,COG2227@1|root,COG2227@2|Bacteria,COG3706@2|Bacteria,2J2MA@203682|Planctomycetes	203682|Planctomycetes	H	Methionine biosynthesis protein MetW	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
k59_102680_1	717605.Theco_4048	1.54e-05	51.6	COG2801@1|root,COG2801@2|Bacteria,1TQH6@1239|Firmicutes,4HHM8@91061|Bacilli,275SU@186822|Paenibacillaceae	91061|Bacilli	L	PFAM Mu transposase, C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	Mu-transpos_C,rve
k59_162937_1	96561.Dole_0794	8.59e-106	319.0	COG0471@1|root,COG0471@2|Bacteria,1MUSA@1224|Proteobacteria,43BQX@68525|delta/epsilon subdivisions,2X71W@28221|Deltaproteobacteria,2MIFV@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Sodium:sulfate symporter transmembrane region	-	-	-	ko:K14445	-	-	-	-	ko00000,ko02000	2.A.47.1	-	-	Na_sulph_symp
k59_208966_1	335543.Sfum_3869	1.18e-108	325.0	COG1801@1|root,COG1801@2|Bacteria,1MXIQ@1224|Proteobacteria,42XHB@68525|delta/epsilon subdivisions,2WSKY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Protein of unknown function DUF72	-	-	-	-	-	-	-	-	-	-	-	-	DUF72
k59_147551_1	1121405.dsmv_2611	6.12e-58	201.0	COG0603@1|root,COG1402@1|root,COG0603@2|Bacteria,COG1402@2|Bacteria,1MXR9@1224|Proteobacteria,42QNA@68525|delta/epsilon subdivisions,2X9RQ@28221|Deltaproteobacteria,2MPA0@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Creatinine amidohydrolase	-	-	3.5.2.10	ko:K01470	ko00330,map00330	-	R01884	RC00615	ko00000,ko00001,ko01000	-	-	-	Creatininase
k59_170838_1	439235.Dalk_1252	3.12e-107	332.0	COG0606@1|root,COG1067@1|root,COG0606@2|Bacteria,COG1067@2|Bacteria,1MWGB@1224|Proteobacteria,42NJD@68525|delta/epsilon subdivisions,2WJFK@28221|Deltaproteobacteria,2MHNT@213118|Desulfobacterales	28221|Deltaproteobacteria	O	Belongs to the peptidase S16 family	-	-	3.4.21.53	ko:K01338,ko:K04076,ko:K04770	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA_32,Lon_C
k59_186381_1	395492.Rleg2_2432	2.96e-69	226.0	COG5362@1|root,COG5362@2|Bacteria,1NKZK@1224|Proteobacteria,2U4BJ@28211|Alphaproteobacteria,4BMKJ@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Terminase RNaseH-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Terminase_6,Terminase_6C
k59_155795_2	204669.Acid345_3614	3e-13	71.2	COG0128@1|root,COG0128@2|Bacteria,3Y3RH@57723|Acidobacteria,2JI7W@204432|Acidobacteriia	204432|Acidobacteriia	E	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	aroA	-	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	EPSP_synthase
k59_110154_1	96561.Dole_0576	5e-37	132.0	COG1149@1|root,COG1149@2|Bacteria,1NCD9@1224|Proteobacteria,42PHV@68525|delta/epsilon subdivisions,2WKDZ@28221|Deltaproteobacteria,2MIUE@213118|Desulfobacterales	28221|Deltaproteobacteria	C	CobQ CobB MinD ParA nucleotide binding domain	-	-	-	-	-	-	-	-	-	-	-	-	CbiA,Fer4
k59_3349_1	375286.mma_0597	2.9e-118	373.0	COG3614@1|root,COG4191@1|root,COG5001@1|root,COG3614@2|Bacteria,COG4191@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,472RR@75682|Oxalobacteraceae	28216|Betaproteobacteria	T	PFAM EAL domain, GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,EAL,GGDEF,PAS_4,PAS_9
k59_72318_1	879212.DespoDRAFT_03003	4.14e-25	103.0	COG4770@1|root,COG5016@1|root,COG4770@2|Bacteria,COG5016@2|Bacteria,1P6RE@1224|Proteobacteria,43BQE@68525|delta/epsilon subdivisions,2X71H@28221|Deltaproteobacteria,2MHKV@213118|Desulfobacterales	28221|Deltaproteobacteria	CI	Conserved carboxylase domain	-	-	4.1.1.3,6.4.1.1	ko:K01571,ko:K01960	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	M00173,M00620	R00217,R00344	RC00040,RC00367	ko00000,ko00001,ko00002,ko01000,ko02000	3.B.1.1.1	-	-	Biotin_lipoyl,HMGL-like,PYC_OADA
k59_72318_2	933262.AXAM01000053_gene2714	2.8e-18	83.2	COG0045@1|root,COG0045@2|Bacteria,1MVCE@1224|Proteobacteria,42M5K@68525|delta/epsilon subdivisions,2WJTS@28221|Deltaproteobacteria,2MHZ2@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit	sucC	-	6.2.1.5	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2261	ATP-grasp_2,Ligase_CoA
k59_216066_1	1121396.KB893112_gene1937	2.91e-09	57.4	2CA4A@1|root,32RQK@2|Bacteria,1RE4A@1224|Proteobacteria,42RRI@68525|delta/epsilon subdivisions,2WND4@28221|Deltaproteobacteria,2MJUU@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4416)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4416
k59_216066_2	671143.DAMO_0090	6.86e-37	137.0	COG1004@1|root,COG1004@2|Bacteria,2NNYN@2323|unclassified Bacteria	2|Bacteria	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	rkpK	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
k59_41573_1	335543.Sfum_1227	4.7e-95	291.0	COG0195@1|root,COG0195@2|Bacteria,1MWT7@1224|Proteobacteria,42MUW@68525|delta/epsilon subdivisions,2WIXI@28221|Deltaproteobacteria,2MQWA@213462|Syntrophobacterales	28221|Deltaproteobacteria	K	Participates in both transcription termination and antitermination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	HHH_5,KH_5,NusA_N,S1
k59_94998_1	335543.Sfum_3531	1.14e-14	74.7	COG1150@1|root,COG2452@1|root,COG1150@2|Bacteria,COG2452@2|Bacteria,1QZ4H@1224|Proteobacteria,43CFH@68525|delta/epsilon subdivisions,2X7QJ@28221|Deltaproteobacteria,2MSKT@213462|Syntrophobacterales	2|Bacteria	C	TIGRFAM DNA binding domain, excisionase family	dld	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03390,ko:K16887,ko:K18930	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	CCG,FAD-oxidase_C,FAD_binding_4,Fer4_7,Fer4_8,HTH_17,MerR_1
k59_133083_2	1167006.UWK_02111	3.14e-53	176.0	COG1639@1|root,COG1639@2|Bacteria,1PDZW@1224|Proteobacteria,42ZIC@68525|delta/epsilon subdivisions,2WUYH@28221|Deltaproteobacteria,2MNC2@213118|Desulfobacterales	28221|Deltaproteobacteria	T	HDOD domain	-	-	-	-	-	-	-	-	-	-	-	-	HDOD
k59_68086_1	290512.Paes_0401	8.21e-38	135.0	COG0020@1|root,COG0020@2|Bacteria,1FDAX@1090|Chlorobi	1090|Chlorobi	H	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	-	-	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
k59_68086_2	997829.HMPREF1121_00225	4.35e-09	57.0	COG0233@1|root,COG0233@2|Bacteria,4NF95@976|Bacteroidetes,2FPZE@200643|Bacteroidia,22XNM@171551|Porphyromonadaceae	976|Bacteroidetes	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
k59_205435_1	1121445.ATUZ01000011_gene626	1.63e-20	94.4	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,2M7UM@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	Two component, sigma54 specific, transcriptional regulator, Fis family	-	-	-	ko:K02481,ko:K07713	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
k59_76519_1	1121405.dsmv_1738	9.86e-82	245.0	COG2077@1|root,COG2077@2|Bacteria,1RAJ9@1224|Proteobacteria,42RE8@68525|delta/epsilon subdivisions,2WNA5@28221|Deltaproteobacteria,2MK12@213118|Desulfobacterales	28221|Deltaproteobacteria	O	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides	tpx	-	1.11.1.15	ko:K11065	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA,Redoxin
k59_152299_1	1120971.AUCA01000036_gene2842	1.73e-30	116.0	COG1309@1|root,COG1309@2|Bacteria,1TRSH@1239|Firmicutes,4H9RC@91061|Bacilli,279QI@186823|Alicyclobacillaceae	91061|Bacilli	K	YsiA-like protein, C-terminal region	fadR	GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0043565,GO:0044212,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:1990837,GO:2000112,GO:2001141	-	ko:K13770	-	-	-	-	ko00000,ko03000	-	-	-	TetR_C_4,TetR_N
k59_129526_1	96561.Dole_2789	2.65e-50	175.0	COG0771@1|root,COG0771@2|Bacteria,1MVYD@1224|Proteobacteria,42MJY@68525|delta/epsilon subdivisions,2WJAQ@28221|Deltaproteobacteria,2MHTV@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	AlaDh_PNT_C,FAD_binding_3,Mur_ligase_C,Mur_ligase_M,NAD_binding_8
k59_121985_1	526222.Desal_1382	8.01e-47	160.0	COG2864@1|root,COG2864@2|Bacteria,1R0SD@1224|Proteobacteria,43D11@68525|delta/epsilon subdivisions,2X88W@28221|Deltaproteobacteria,2MHDG@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	formate dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_121985_2	1232437.KL661988_gene190	8.91e-62	202.0	COG3303@1|root,COG3303@2|Bacteria,1QX6Q@1224|Proteobacteria,42MHA@68525|delta/epsilon subdivisions,2WMF3@28221|Deltaproteobacteria,2MK9F@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Cytochrome c554 and c-prime	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C552,Cytochrome_C554,Paired_CXXCH_1
k59_30986_1	246200.SPO2153	2.57e-15	82.0	COG0303@1|root,COG0303@2|Bacteria,1MVD5@1224|Proteobacteria,2TQRI@28211|Alphaproteobacteria,4NAT1@97050|Ruegeria	28211|Alphaproteobacteria	H	Molybdenum cofactor biosynthesis protein A	moeA	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
k59_15802_1	593750.Metfor_2014	1.47e-07	55.8	COG2865@1|root,arCOG03296@2157|Archaea,arCOG06876@2157|Archaea,2XV8V@28890|Euryarchaeota,2NB2V@224756|Methanomicrobia	224756|Methanomicrobia	K	Transcriptional regulator	-	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AlbA_2,HATPase_c_4
k59_212855_1	556269.ACDQ01000016_gene505	7.11e-38	155.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,2VJ57@28216|Betaproteobacteria,4724B@75682|Oxalobacteraceae	28216|Betaproteobacteria	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
k59_61501_2	388399.SSE37_25353	5.82e-11	64.3	2BTNS@1|root,32NVS@2|Bacteria,1RJWC@1224|Proteobacteria,2UAEA@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_76530_1	1201293.AKXQ01000024_gene3866	1.9e-26	110.0	COG2067@1|root,COG2067@2|Bacteria,1R3SS@1224|Proteobacteria,1S0X2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	long-chain fatty acid transport protein	-	-	-	ko:K06076	-	-	-	-	ko00000,ko02000	1.B.9	-	-	Toluene_X
k59_205442_1	66692.ABC2696	2.57e-56	193.0	COG0673@1|root,COG0673@2|Bacteria,1TPT5@1239|Firmicutes,4HAPJ@91061|Bacilli,1ZDI9@1386|Bacillus	91061|Bacilli	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
k59_61504_1	1121447.JONL01000002_gene1998	5.26e-89	285.0	28HB2@1|root,2Z7N8@2|Bacteria,1P4RV@1224|Proteobacteria,42NVF@68525|delta/epsilon subdivisions,2WKNV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Fatty acid cis/trans isomerase (CTI)	-	-	-	-	-	-	-	-	-	-	-	-	CTI
k59_53756_1	643562.Daes_2482	4.79e-55	193.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2WJ8D@28221|Deltaproteobacteria,2M9AP@213115|Desulfovibrionales	28221|Deltaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
k59_84024_1	1121413.JMKT01000015_gene318	1.6e-38	153.0	COG2203@1|root,COG4191@1|root,COG2203@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MC4@68525|delta/epsilon subdivisions,2WIZU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase A domain protein	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	GAF,HAMP,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,PocR,Response_reg,sCache_2
k59_84024_2	1499967.BAYZ01000036_gene2437	6.55e-87	266.0	COG0330@1|root,COG0330@2|Bacteria,2NP3W@2323|unclassified Bacteria	2|Bacteria	O	HflC and HflK could encode or regulate a protease	hflK	-	-	ko:K04088	-	M00742	-	-	ko00000,ko00002,ko01000	-	-	-	Band_7
k59_137196_1	118163.Ple7327_3825	1.84e-10	67.8	COG0428@1|root,COG0664@1|root,COG0428@2|Bacteria,COG0664@2|Bacteria,1G2YK@1117|Cyanobacteria,3VN15@52604|Pleurocapsales	1117|Cyanobacteria	PT	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Zip,cNMP_binding
k59_8273_1	1304885.AUEY01000011_gene1736	4.65e-61	189.0	COG4802@1|root,COG4802@2|Bacteria,1RI70@1224|Proteobacteria,42SXJ@68525|delta/epsilon subdivisions,2WP19@28221|Deltaproteobacteria,2MKJ4@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM Ferredoxin thioredoxin reductase catalytic beta chain	-	-	-	-	-	-	-	-	-	-	-	-	FeThRed_B
k59_46170_1	909663.KI867150_gene248	3e-208	588.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,42N0C@68525|delta/epsilon subdivisions,2WJQQ@28221|Deltaproteobacteria,2MQT7@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	PFAM Aldehyde dehydrogenase	-	-	1.2.1.16,1.2.1.18,1.2.1.20,1.2.1.27,1.2.1.3,1.2.1.79,1.2.1.9	ko:K00128,ko:K00131,ko:K00135,ko:K00140	ko00010,ko00030,ko00053,ko00071,ko00250,ko00280,ko00310,ko00330,ko00340,ko00350,ko00380,ko00410,ko00561,ko00562,ko00620,ko00625,ko00640,ko00650,ko00760,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00053,map00071,map00250,map00280,map00310,map00330,map00340,map00350,map00380,map00410,map00561,map00562,map00620,map00625,map00640,map00650,map00760,map00903,map00981,map01100,map01110,map01120,map01130,map01200	M00013,M00027,M00135,M00308,M00633	R00264,R00631,R00705,R00706,R00710,R00713,R00714,R00904,R00922,R00935,R01058,R01752,R01986,R02401,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00004,RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500,RC02723,RC02817	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
k59_129546_2	349521.HCH_00424	4.54e-20	86.7	COG1280@1|root,COG1280@2|Bacteria,1MXAI@1224|Proteobacteria,1RPWN@1236|Gammaproteobacteria,1XRGM@135619|Oceanospirillales	135619|Oceanospirillales	E	LysE type translocator	-	-	-	-	-	-	-	-	-	-	-	-	LysE
k59_190174_1	1121405.dsmv_1951	4.08e-59	189.0	COG1014@1|root,COG1014@2|Bacteria,1N12F@1224|Proteobacteria,42NN1@68525|delta/epsilon subdivisions,2WNNF@28221|Deltaproteobacteria,2MQ0Y@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Pyruvate ferredoxin/flavodoxin oxidoreductase	-	-	1.2.7.1	ko:K00172	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	POR
k59_61521_1	1190603.AJYD01000008_gene2093	2.01e-12	68.6	COG3274@1|root,COG3274@2|Bacteria,1PX98@1224|Proteobacteria,1RMGG@1236|Gammaproteobacteria,1XY9X@135623|Vibrionales	135623|Vibrionales	S	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
k59_122006_1	1096546.WYO_5213	2.42e-52	171.0	COG3039@1|root,COG3039@2|Bacteria,1MVDK@1224|Proteobacteria,2TS7B@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DUF772
k59_646_1	933262.AXAM01000002_gene515	2.62e-116	343.0	COG4822@1|root,COG4822@2|Bacteria,1P36Y@1224|Proteobacteria,42P9C@68525|delta/epsilon subdivisions,2WK8C@28221|Deltaproteobacteria,2MIFS@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Catalyzes the insertion of Co(2 ) into sirohydrochlorin	cbiKp	GO:0003674,GO:0003824,GO:0004325,GO:0005488,GO:0005575,GO:0005623,GO:0008150,GO:0009987,GO:0016043,GO:0016829,GO:0016852,GO:0020037,GO:0022607,GO:0042597,GO:0043167,GO:0043169,GO:0043933,GO:0044085,GO:0044464,GO:0046872,GO:0046906,GO:0046914,GO:0048037,GO:0050897,GO:0051259,GO:0051262,GO:0051266,GO:0065003,GO:0071840,GO:0097159,GO:1901363	4.99.1.3	ko:K02190	ko00860,ko01100,map00860,map01100	-	R05807	RC01012	ko00000,ko00001,ko01000	-	-	-	CbiK
k59_76557_1	933262.AXAM01000109_gene2064	3.08e-33	127.0	COG0845@1|root,COG0845@2|Bacteria,1R443@1224|Proteobacteria,43ASW@68525|delta/epsilon subdivisions,2X676@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
k59_76557_2	1123277.KB893176_gene3721	0.000114	45.1	COG0841@1|root,COG0841@2|Bacteria,4NDZG@976|Bacteroidetes,47N6C@768503|Cytophagia	976|Bacteroidetes	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_129557_1	887062.HGR_01627	9.98e-61	199.0	COG1703@1|root,COG1703@2|Bacteria,1MVI0@1224|Proteobacteria,2VIRF@28216|Betaproteobacteria,4AA9Q@80864|Comamonadaceae	28216|Betaproteobacteria	E	LAO AO transport system ATPase	argK	-	-	ko:K07588	-	-	-	-	ko00000,ko01000	-	-	-	ArgK
k59_31011_1	1121405.dsmv_2939	4.94e-89	272.0	COG2214@1|root,COG2214@2|Bacteria,1NW19@1224|Proteobacteria,43012@68525|delta/epsilon subdivisions,2WVBG@28221|Deltaproteobacteria,2MNIU@213118|Desulfobacterales	28221|Deltaproteobacteria	O	PFAM heat shock protein DnaJ domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_46177_1	909663.KI867150_gene2533	6.85e-22	92.8	COG0059@1|root,COG0059@2|Bacteria,1MV7M@1224|Proteobacteria,42MRS@68525|delta/epsilon subdivisions,2WJW8@28221|Deltaproteobacteria,2MQBF@213462|Syntrophobacterales	28221|Deltaproteobacteria	EH	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate	ilvC	-	1.1.1.86	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R03051,R04439,R04440,R05068,R05069,R05071	RC00726,RC00836,RC00837,RC01726	ko00000,ko00001,ko00002,ko01000	-	-	-	IlvC,IlvN
k59_220706_1	1232437.KL662022_gene857	1.08e-27	107.0	COG1149@1|root,COG1149@2|Bacteria,1NCD9@1224|Proteobacteria,42PHV@68525|delta/epsilon subdivisions,2WKDZ@28221|Deltaproteobacteria,2MIUE@213118|Desulfobacterales	28221|Deltaproteobacteria	C	CobQ CobB MinD ParA nucleotide binding domain	-	-	-	-	-	-	-	-	-	-	-	-	CbiA,Fer4
k59_220706_2	96561.Dole_0577	5.16e-118	346.0	COG1149@1|root,COG1149@2|Bacteria,1MVPB@1224|Proteobacteria,42MJ5@68525|delta/epsilon subdivisions,2WJ9M@28221|Deltaproteobacteria,2MIKP@213118|Desulfobacterales	28221|Deltaproteobacteria	C	CobQ CobB MinD ParA nucleotide binding domain	-	-	-	-	-	-	-	-	-	-	-	-	CbiA,Fer4
k59_137215_1	269482.Bcep1808_1171	6.95e-43	169.0	28JKJ@1|root,2Z9DD@2|Bacteria,1MUN2@1224|Proteobacteria,2W6XZ@28216|Betaproteobacteria,1KD72@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Phage P22-like portal protein	-	-	-	-	-	-	-	-	-	-	-	-	P22_portal
k59_235776_1	1121405.dsmv_2376	1.36e-83	271.0	COG1148@1|root,COG1148@2|Bacteria,1QUM4@1224|Proteobacteria,42MPP@68525|delta/epsilon subdivisions,2WJ3U@28221|Deltaproteobacteria,2MIA4@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_7,Pyr_redox_2
k59_53784_1	1121405.dsmv_0334	9.02e-44	150.0	COG0517@1|root,COG0517@2|Bacteria,1RKZ2@1224|Proteobacteria,42SYQ@68525|delta/epsilon subdivisions,2WP9E@28221|Deltaproteobacteria,2MPQX@213118|Desulfobacterales	28221|Deltaproteobacteria	S	PFAM CBS domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CBS
k59_190198_1	1121451.DESAM_21367	5.15e-76	241.0	COG4656@1|root,COG4656@2|Bacteria,1PJE1@1224|Proteobacteria,42P69@68525|delta/epsilon subdivisions,2WIM9@28221|Deltaproteobacteria,2M9JQ@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	RnfC Barrel sandwich hybrid domain	-	-	-	-	-	-	-	-	-	-	-	-	Complex1_51K,Fer4_17,RnfC_N,SLBB
k59_23463_1	644282.Deba_0066	1.18e-44	161.0	COG2203@1|root,COG4251@1|root,COG2203@2|Bacteria,COG4251@2|Bacteria,1RGKE@1224|Proteobacteria,43EF4@68525|delta/epsilon subdivisions,2X87I@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	SMART ATP-binding region ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
k59_15837_2	1408422.JHYF01000006_gene1242	3.06e-06	53.1	COG2266@1|root,COG2266@2|Bacteria,1UJC9@1239|Firmicutes,25F1Q@186801|Clostridia,36JUG@31979|Clostridiaceae	186801|Clostridia	H	MobA-like NTP transferase domain	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_3
k59_38685_1	207559.Dde_1553	1.94e-134	390.0	COG0686@1|root,COG0686@2|Bacteria,1QTX1@1224|Proteobacteria,42MSF@68525|delta/epsilon subdivisions,2WKJ5@28221|Deltaproteobacteria,2M87G@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	Belongs to the AlaDH PNT family	ald	-	1.4.1.1	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	-	R00396	RC00008	ko00000,ko00001,ko01000	-	-	iAF987.Gmet_1099	AlaDh_PNT_C,AlaDh_PNT_N
k59_160005_1	794903.OPIT5_15865	9.46e-65	206.0	COG1028@1|root,COG1028@2|Bacteria,46UZ1@74201|Verrucomicrobia,3K7C4@414999|Opitutae	414999|Opitutae	IQ	PFAM short-chain dehydrogenase reductase SDR	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
k59_175139_2	1284352.AOIG01000014_gene3437	5.42e-37	145.0	COG2730@1|root,COG2730@2|Bacteria,1TZ4H@1239|Firmicutes,4I8BN@91061|Bacilli,26ZHZ@186822|Paenibacillaceae	91061|Bacilli	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_152349_1	1232437.KL661960_gene3054	1.52e-05	48.9	COG0589@1|root,COG0589@2|Bacteria,1MVZS@1224|Proteobacteria,42QGY@68525|delta/epsilon subdivisions,2WKHR@28221|Deltaproteobacteria,2MJDT@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
k59_23479_1	452637.Oter_1072	3.06e-63	197.0	COG2303@1|root,COG2303@2|Bacteria	2|Bacteria	E	choline dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	DAO,GMC_oxred_C,GMC_oxred_N,NAD_binding_8,Pyr_redox_2
k59_23479_2	1120983.KB894572_gene2997	1.1e-42	143.0	2CEUC@1|root,32S0I@2|Bacteria,1MZ90@1224|Proteobacteria,2UCBC@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_46192_1	690850.Desaf_0050	9.61e-21	94.0	COG0115@1|root,COG0115@2|Bacteria,1MVB0@1224|Proteobacteria,42MKX@68525|delta/epsilon subdivisions,2WKXU@28221|Deltaproteobacteria,2M80I@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
k59_144730_1	1121405.dsmv_0393	1.83e-23	97.4	COG1294@1|root,COG1294@2|Bacteria,1MURP@1224|Proteobacteria,42NHN@68525|delta/epsilon subdivisions,2WJ4S@28221|Deltaproteobacteria,2MHWJ@213118|Desulfobacterales	28221|Deltaproteobacteria	C	TIGRFAM cytochrome d ubiquinol oxidase, subunit II	cydB	-	1.10.3.14	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	Cyt_bd_oxida_II
k59_106887_1	439235.Dalk_0331	3.16e-119	353.0	2C0YB@1|root,2ZAH2@2|Bacteria,1R8PK@1224|Proteobacteria,42QK8@68525|delta/epsilon subdivisions,2WKZK@28221|Deltaproteobacteria,2MICB@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_15851_1	335543.Sfum_3548	2.29e-62	207.0	COG0508@1|root,COG0508@2|Bacteria,1MUJD@1224|Proteobacteria,42N18@68525|delta/epsilon subdivisions,2WJSK@28221|Deltaproteobacteria,2MRUP@213462|Syntrophobacterales	28221|Deltaproteobacteria	I	2-oxoacid dehydrogenases acyltransferase (catalytic domain)	sucB	-	2.3.1.12,2.3.1.61	ko:K00627,ko:K00658	ko00010,ko00020,ko00310,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00310,map00620,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032,M00307	R00209,R02569,R02570,R02571,R08549	RC00004,RC02727,RC02742,RC02833,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2766	2-oxoacid_dh,Biotin_lipoyl,E3_binding
k59_106889_1	96561.Dole_1953	5.12e-64	219.0	COG1111@1|root,COG1205@1|root,COG1111@2|Bacteria,COG1205@2|Bacteria,1QU0I@1224|Proteobacteria,42M4R@68525|delta/epsilon subdivisions,2WK1V@28221|Deltaproteobacteria,2MI86@213118|Desulfobacterales	28221|Deltaproteobacteria	L	DEAD DEAH box helicase	yprA	-	-	ko:K06877	-	-	-	-	ko00000	-	-	-	DEAD,DUF1998,Helicase_C,RNase_H_2
k59_84063_1	318161.Sden_1137	9.89e-57	191.0	COG4974@1|root,COG4974@2|Bacteria,1MVAN@1224|Proteobacteria,1S1WF@1236|Gammaproteobacteria,2QEIK@267890|Shewanellaceae	1236|Gammaproteobacteria	L	Phage integrase, N-terminal SAM-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
k59_160018_1	439235.Dalk_2279	2.4e-106	338.0	COG1033@1|root,COG4191@1|root,COG1033@2|Bacteria,COG4191@2|Bacteria,1MUE1@1224|Proteobacteria,42ME2@68525|delta/epsilon subdivisions,2WJRI@28221|Deltaproteobacteria,2MJQ7@213118|Desulfobacterales	28221|Deltaproteobacteria	K	MMPL family	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	GGDEF,LolA_like,MMPL,cNMP_binding
k59_137246_1	96561.Dole_2153	1.38e-53	189.0	COG0358@1|root,COG0358@2|Bacteria,1MUHC@1224|Proteobacteria,42MDZ@68525|delta/epsilon subdivisions,2WJ9Y@28221|Deltaproteobacteria,2MHRW@213118|Desulfobacterales	28221|Deltaproteobacteria	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2
k59_114365_1	357808.RoseRS_0321	6.53e-19	86.7	COG0037@1|root,COG0634@1|root,COG0037@2|Bacteria,COG0634@2|Bacteria,2G6AD@200795|Chloroflexi,374VQ@32061|Chloroflexia	32061|Chloroflexia	D	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	2.4.2.8,6.3.4.19	ko:K00760,ko:K04075	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245,R09597	RC00063,RC00122,RC02633,RC02634	ko00000,ko00001,ko01000,ko03016	-	-	-	ATP_bind_3,Pribosyltran,TilS,TilS_C
k59_129597_1	1189612.A33Q_2737	6.77e-13	73.2	COG1672@1|root,COG1672@2|Bacteria,4NGM3@976|Bacteroidetes,47VKT@768503|Cytophagia	976|Bacteroidetes	S	ATPase (AAA superfamily)	-	-	-	-	-	-	-	-	-	-	-	-	ATPase_2
k59_122054_1	1229172.JQFA01000002_gene3687	3.28e-90	280.0	COG5433@1|root,COG5433@2|Bacteria,1G0VN@1117|Cyanobacteria,1H992@1150|Oscillatoriales	1117|Cyanobacteria	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_assoc
k59_8316_1	1167006.UWK_02898	2.94e-54	188.0	COG1038@1|root,COG1038@2|Bacteria,1R7P1@1224|Proteobacteria,42PQ3@68525|delta/epsilon subdivisions,2WJK5@28221|Deltaproteobacteria,2MJRR@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Conserved carboxylase domain	-	-	6.4.1.1	ko:K01958	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	M00173	R00344	RC00040,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_lipoyl,HMGL-like,PYC_OADA
k59_160024_1	641107.CDLVIII_0648	7.37e-81	242.0	COG1943@1|root,COG1943@2|Bacteria,1TSQ0@1239|Firmicutes,25CMS@186801|Clostridia,36GEU@31979|Clostridiaceae	186801|Clostridia	L	PFAM transposase IS200-family protein	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
k59_76611_1	1265505.ATUG01000001_gene4233	4.16e-20	87.0	COG1177@1|root,COG1177@2|Bacteria,1MVC5@1224|Proteobacteria,42MIJ@68525|delta/epsilon subdivisions,2WJKS@28221|Deltaproteobacteria,2MKBN@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K11070	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	BPD_transp_1
k59_76611_2	1121918.ARWE01000001_gene562	7.17e-64	202.0	COG1176@1|root,COG1176@2|Bacteria,1MVFG@1224|Proteobacteria,43AFR@68525|delta/epsilon subdivisions,2WKHP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K11071	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	BPD_transp_1
k59_122061_1	96561.Dole_2034	3.42e-105	315.0	COG0002@1|root,COG0002@2|Bacteria,1MVJ6@1224|Proteobacteria,42MDN@68525|delta/epsilon subdivisions,2WINX@28221|Deltaproteobacteria,2MI9X@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde	argC	-	1.2.1.38	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R03443	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
k59_91660_1	1122221.JHVI01000021_gene2455	1.14e-05	51.2	COG2208@1|root,COG2208@2|Bacteria	2|Bacteria	T	phosphoserine phosphatase activity	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	HATPase_c_2,SpoIIE
k59_122592_2	335543.Sfum_0456	7.63e-21	90.5	COG1703@1|root,COG1703@2|Bacteria,1MVI0@1224|Proteobacteria,42NBN@68525|delta/epsilon subdivisions,2WK8A@28221|Deltaproteobacteria,2MQRT@213462|Syntrophobacterales	28221|Deltaproteobacteria	E	TIGRFAM LAO AO transport system ATPase	-	-	-	ko:K07588	-	-	-	-	ko00000,ko01000	-	-	-	ArgK
k59_54316_1	1232437.KL662015_gene1287	1.59e-102	298.0	COG1765@1|root,COG1765@2|Bacteria,1N1T3@1224|Proteobacteria,42UFR@68525|delta/epsilon subdivisions,2WQ83@28221|Deltaproteobacteria,2MMSD@213118|Desulfobacterales	28221|Deltaproteobacteria	O	Protein of unknown function (DUF3795)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3795
k59_46745_1	595460.RRSWK_02689	4.4e-08	59.3	COG0705@1|root,COG0705@2|Bacteria	2|Bacteria	S	proteolysis	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
k59_12290_1	335543.Sfum_1198	8.67e-99	302.0	COG0058@1|root,COG0058@2|Bacteria,1MW4J@1224|Proteobacteria,42MEQ@68525|delta/epsilon subdivisions,2WIPF@28221|Deltaproteobacteria,2MQYI@213462|Syntrophobacterales	28221|Deltaproteobacteria	G	Carbohydrate phosphorylase	-	-	2.4.1.1,2.4.1.11	ko:K00688,ko:K16153	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R00292,R02111	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT3,GT35	-	DUF3417,Phosphorylase
k59_41795_1	1541065.JRFE01000008_gene4992	3.53e-41	152.0	COG0745@1|root,COG4251@1|root,COG0745@2|Bacteria,COG4251@2|Bacteria,1GHFQ@1117|Cyanobacteria	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HAMP,HATPase_c,HisKA,PAS_3,PAS_9,Response_reg,dCache_1
k59_80313_1	706587.Desti_3938	1.67e-17	82.4	COG1847@1|root,COG1847@2|Bacteria,1RB1P@1224|Proteobacteria,42QPK@68525|delta/epsilon subdivisions,2WN58@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM Single-stranded nucleic acid binding R3H	-	-	-	ko:K06346	-	-	-	-	ko00000	-	-	-	Jag_N,KH_4,R3H
k59_80313_2	398767.Glov_3641	1e-11	66.2	COG0486@1|root,COG0486@2|Bacteria,1MUCQ@1224|Proteobacteria,42M6T@68525|delta/epsilon subdivisions,2WIWY@28221|Deltaproteobacteria,43TPQ@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34	mnmE	-	-	ko:K03650	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko01000,ko03016	-	-	-	MMR_HSR1,MnmE_helical,TrmE_N
k59_223890_1	338963.Pcar_2585	1.57e-67	227.0	COG1032@1|root,COG5011@1|root,COG1032@2|Bacteria,COG5011@2|Bacteria,1MV5G@1224|Proteobacteria,42MPT@68525|delta/epsilon subdivisions,2WJG9@28221|Deltaproteobacteria,43RXX@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Uncharacterized protein conserved in bacteria (DUF2344)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2344,Radical_SAM
k59_49623_1	118168.MC7420_7391	4.7e-62	202.0	COG3039@1|root,COG3039@2|Bacteria,1G3YX@1117|Cyanobacteria,1H8DI@1150|Oscillatoriales	1117|Cyanobacteria	L	Transposase DDE domain	-	-	-	ko:K07481	-	-	-	-	ko00000	-	-	-	DDE_Tnp_1_2,DUF772
k59_57650_1	269799.Gmet_3169	6.53e-97	297.0	COG1866@1|root,COG1866@2|Bacteria,1MWXN@1224|Proteobacteria,42N5Y@68525|delta/epsilon subdivisions,2WJMT@28221|Deltaproteobacteria,43TB3@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA	pckA	-	4.1.1.49	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00170	R00341	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_3169	PEPCK_ATP
k59_186723_1	316067.Geob_1601	1.11e-26	113.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42P9E@68525|delta/epsilon subdivisions,2WMH3@28221|Deltaproteobacteria,43SU5@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	histidine kinase, HAMP	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4
k59_41808_1	335543.Sfum_0154	1e-190	546.0	COG0073@1|root,COG0143@1|root,COG0073@2|Bacteria,COG0143@2|Bacteria,1MUBY@1224|Proteobacteria,42N1K@68525|delta/epsilon subdivisions,2WIT6@28221|Deltaproteobacteria,2MQAG@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	-	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g,tRNA_bind
k59_49632_1	390874.Tpet_0358	9.36e-89	279.0	COG0500@1|root,COG1181@1|root,COG1181@2|Bacteria,COG2226@2|Bacteria,2GBZA@200918|Thermotogae	200918|Thermotogae	F	Belongs to the D-alanine--D-alanine ligase family	-	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Methyltransf_25
k59_193406_1	1121456.ATVA01000013_gene1157	2.77e-80	249.0	COG0492@1|root,COG0492@2|Bacteria,1R82E@1224|Proteobacteria,42PSM@68525|delta/epsilon subdivisions,2WJYX@28221|Deltaproteobacteria,2M8GU@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,Pyr_redox_3
k59_102993_1	1120970.AUBZ01000002_gene872	2.79e-20	94.4	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,1RN52@1236|Gammaproteobacteria,4659D@72275|Alteromonadaceae	1236|Gammaproteobacteria	T	COG0642 Signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE5,HATPase_c,HisKA,PAS,PAS_4,PAS_9
k59_232135_1	1121405.dsmv_2979	5.96e-07	50.4	COG1924@1|root,COG1924@2|Bacteria,1R6HU@1224|Proteobacteria,42PM0@68525|delta/epsilon subdivisions,2WJRP@28221|Deltaproteobacteria,2MHRM@213118|Desulfobacterales	28221|Deltaproteobacteria	I	PFAM BadF BadG BcrA BcrD ATPase family	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG
k59_232135_2	1121403.AUCV01000062_gene3686	1.32e-08	55.8	COG1775@1|root,COG1775@2|Bacteria,1NNW9@1224|Proteobacteria,42PEQ@68525|delta/epsilon subdivisions,2WINV@28221|Deltaproteobacteria,2MHPI@213118|Desulfobacterales	28221|Deltaproteobacteria	E	2-hydroxyglutaryl-CoA dehydratase, D-component	yjiM	-	-	-	-	-	-	-	-	-	-	-	HGD-D
k59_232135_3	1121396.KB893090_gene182	1.36e-17	79.7	COG5266@1|root,COG5266@2|Bacteria,1NAWR@1224|Proteobacteria,42W0H@68525|delta/epsilon subdivisions,2WRKH@28221|Deltaproteobacteria,2MM3X@213118|Desulfobacterales	28221|Deltaproteobacteria	P	PFAM Nickel transport complex, NikM subunit, transmembrane	-	-	-	ko:K16915	ko02010,map02010	M00246	-	-	ko00000,ko00001,ko00002,ko02000	-	-	-	-
k59_41815_1	1149133.ppKF707_5127	8.47e-47	166.0	COG4623@1|root,COG4623@2|Bacteria,1MWDS@1224|Proteobacteria,1RM8W@1236|Gammaproteobacteria,1YFKK@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	M	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella	mltF2	GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944	-	ko:K18691	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	SBP_bac_3,SLT
k59_125862_1	1125863.JAFN01000001_gene1160	4.46e-129	378.0	COG0683@1|root,COG0683@2|Bacteria,1MWQB@1224|Proteobacteria,42PN2@68525|delta/epsilon subdivisions,2WM53@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	PFAM Extracellular ligand-binding receptor	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
k59_12306_3	1410630.JNKP01000007_gene507	9.91e-13	71.2	COG0740@1|root,COG0740@2|Bacteria,1TQ91@1239|Firmicutes,247QY@186801|Clostridia,27I8S@186928|unclassified Lachnospiraceae	186801|Clostridia	OU	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
k59_64687_1	709032.Sulku_1619	9.44e-31	125.0	COG0715@1|root,COG0834@1|root,COG2199@1|root,COG0715@2|Bacteria,COG0834@2|Bacteria,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,42MCD@68525|delta/epsilon subdivisions,2YN6K@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	ET	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,NMT1,SBP_bac_3
k59_80353_1	933262.AXAM01000027_gene2080	1.23e-25	95.9	2E3TC@1|root,32YQV@2|Bacteria,1N7A9@1224|Proteobacteria,42VBE@68525|delta/epsilon subdivisions,2WSGC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	copG family	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_80353_2	519989.ECTPHS_07936	5.21e-48	154.0	COG4115@1|root,COG4115@2|Bacteria,1MZBP@1224|Proteobacteria,1S99Z@1236|Gammaproteobacteria,1WYX1@135613|Chromatiales	135613|Chromatiales	S	TIGRFAM Addiction module toxin, Txe YoeB	-	-	-	ko:K19158	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	YoeB_toxin
k59_80353_3	572477.Alvin_0336	7.16e-32	113.0	COG2161@1|root,COG2161@2|Bacteria,1N6X6@1224|Proteobacteria,1SDQ0@1236|Gammaproteobacteria,1WZ3Y@135613|Chromatiales	135613|Chromatiales	D	Antitoxin component of a toxin-antitoxin (TA) module	-	-	-	ko:K19159	-	-	-	-	ko00000,ko02048	-	-	-	PhdYeFM_antitox
k59_64690_1	335543.Sfum_1361	6.66e-172	496.0	COG0481@1|root,COG0481@2|Bacteria,1MVZA@1224|Proteobacteria,42M3D@68525|delta/epsilon subdivisions,2WJEA@28221|Deltaproteobacteria,2MQ6G@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,EFG_II,GTP_EFTU,GTP_EFTU_D2,LepA_C
k59_12312_1	472759.Nhal_0372	1.31e-101	305.0	COG1260@1|root,COG1260@2|Bacteria,1N0D9@1224|Proteobacteria,1RZ5M@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	Myo-inositol-1-phosphate synthase	-	-	5.5.1.4	ko:K01858	ko00521,ko00562,ko01100,ko01130,map00521,map00562,map01100,map01130	-	R07324	RC01804	ko00000,ko00001,ko01000	-	-	-	Inos-1-P_synth
k59_216438_1	555779.Dthio_PD1799	2.69e-72	242.0	COG1924@1|root,COG3580@1|root,COG1924@2|Bacteria,COG3580@2|Bacteria,1PKG6@1224|Proteobacteria,42MY4@68525|delta/epsilon subdivisions,2WJFI@28221|Deltaproteobacteria,2M8T9@213115|Desulfovibrionales	28221|Deltaproteobacteria	I	ATPase BadF BadG BcrA BcrD type	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG,DUF2229
k59_133507_1	439235.Dalk_1210	8.04e-50	177.0	COG2208@1|root,COG5000@1|root,COG2208@2|Bacteria,COG5000@2|Bacteria,1RCHY@1224|Proteobacteria,42R1G@68525|delta/epsilon subdivisions,2WMR7@28221|Deltaproteobacteria,2MJNU@213118|Desulfobacterales	28221|Deltaproteobacteria	T	protein phosphatase 2C domain protein	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	HAMP,SpoIIE
k59_141092_1	933262.AXAM01000017_gene3132	2.29e-39	150.0	COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,1MUKF@1224|Proteobacteria,42N3S@68525|delta/epsilon subdivisions,2WJ5P@28221|Deltaproteobacteria,2MI3T@213118|Desulfobacterales	28221|Deltaproteobacteria	S	DNA internalization-related competence protein ComEC Rec2	-	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131,Lactamase_B
k59_3593_1	1268239.PALB_27440	3.15e-31	127.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,1RNQN@1236|Gammaproteobacteria,2Q5CT@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_8
k59_41841_1	706587.Desti_0366	6.58e-73	229.0	COG0483@1|root,COG0483@2|Bacteria,1NVDS@1224|Proteobacteria,42ZN3@68525|delta/epsilon subdivisions,2WUWR@28221|Deltaproteobacteria,2MRNA@213462|Syntrophobacterales	28221|Deltaproteobacteria	G	Inositol monophosphatase family	-	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
k59_223904_1	314266.SKA58_17398	1.13e-32	129.0	COG1322@1|root,COG1322@2|Bacteria,1MWHV@1224|Proteobacteria,2TTX6@28211|Alphaproteobacteria,2K0B3@204457|Sphingomonadales	204457|Sphingomonadales	S	DNA recombination protein	rmuC	-	-	ko:K09760	-	-	-	-	ko00000	-	-	-	RmuC
k59_147822_1	351627.Csac_0587	2.96e-19	86.7	2E720@1|root,331KM@2|Bacteria,1V6XB@1239|Firmicutes,24FI2@186801|Clostridia	186801|Clostridia	S	TraX protein	-	-	-	-	-	-	-	-	-	-	-	-	TraX
k59_110628_1	439235.Dalk_4310	1.97e-83	258.0	COG0636@1|root,COG0636@2|Bacteria,1MZ0M@1224|Proteobacteria,42T8K@68525|delta/epsilon subdivisions,2WPRA@28221|Deltaproteobacteria,2MMV3@213118|Desulfobacterales	28221|Deltaproteobacteria	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	-	-	-	-	-	-	-	-	-	-	-	-	ATP-synt_C
k59_125891_1	1379281.AVAG01000077_gene1605	1.06e-142	425.0	COG0480@1|root,COG0480@2|Bacteria,1MUCV@1224|Proteobacteria,42M4T@68525|delta/epsilon subdivisions,2WIM7@28221|Deltaproteobacteria,2M882@213115|Desulfovibrionales	28221|Deltaproteobacteria	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
k59_34893_1	706587.Desti_3731	1.94e-51	169.0	COG0745@1|root,COG0745@2|Bacteria,1MZPD@1224|Proteobacteria,42U2Y@68525|delta/epsilon subdivisions,2WQ1I@28221|Deltaproteobacteria,2MRWP@213462|Syntrophobacterales	28221|Deltaproteobacteria	KT	Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Usp
k59_34893_2	1121405.dsmv_2389	8.21e-09	55.8	COG1788@1|root,COG1788@2|Bacteria,1NGS5@1224|Proteobacteria,42S03@68525|delta/epsilon subdivisions,2WNW5@28221|Deltaproteobacteria,2MQ1F@213118|Desulfobacterales	28221|Deltaproteobacteria	I	PFAM Coenzyme A transferase	-	-	2.8.3.12	ko:K01039	ko00643,ko00650,ko01120,map00643,map00650,map01120	-	R04000,R05509	RC00012,RC00131,RC00137	ko00000,ko00001,ko01000	-	-	-	CoA_trans
k59_34894_1	96561.Dole_2132	1.75e-68	215.0	COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,42QN5@68525|delta/epsilon subdivisions,2WMD7@28221|Deltaproteobacteria,2MJC9@213118|Desulfobacterales	28221|Deltaproteobacteria	V	PFAM ABC transporter related	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
k59_224537_2	1121422.AUMW01000010_gene1036	2.4e-71	224.0	COG1024@1|root,COG1024@2|Bacteria,1TQ89@1239|Firmicutes,247RK@186801|Clostridia,26121@186807|Peptococcaceae	186801|Clostridia	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	4.2.1.17,4.2.1.18	ko:K01715,ko:K13766	ko00280,ko00650,ko01100,ko01200,map00280,map00650,map01100,map01200	M00036	R02085,R03026	RC00831,RC02416	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
k59_80990_1	335543.Sfum_2163	5.17e-148	427.0	COG1702@1|root,COG1702@2|Bacteria,1MVDV@1224|Proteobacteria,42N58@68525|delta/epsilon subdivisions,2WIQS@28221|Deltaproteobacteria,2MQWK@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	PhoH-like protein	phoH2	-	-	ko:K06217	-	-	-	-	ko00000	-	-	-	PhoH
k59_134142_1	1167006.UWK_02231	7.7e-56	192.0	COG3666@1|root,COG3666@2|Bacteria,1N3QR@1224|Proteobacteria,42N7X@68525|delta/epsilon subdivisions,2WMM9@28221|Deltaproteobacteria,2MMU3@213118|Desulfobacterales	28221|Deltaproteobacteria	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_6,DUF772
k59_58384_1	716544.wcw_0905	0.000175	47.4	COG0727@1|root,COG0727@2|Bacteria,2JG8E@204428|Chlamydiae	204428|Chlamydiae	S	Putative zinc- or iron-chelating domain	-	-	-	ko:K06940	-	-	-	-	ko00000	-	-	-	CxxCxxCC
k59_187381_1	398720.MED217_17915	8.43e-39	141.0	COG2801@1|root,COG2801@2|Bacteria,4NF3Q@976|Bacteroidetes,1HZT4@117743|Flavobacteriia	976|Bacteroidetes	L	COG2801 Transposase and inactivated derivatives	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve,rve_2
k59_163878_1	1121405.dsmv_1081	1.09e-91	286.0	COG1333@1|root,COG1333@2|Bacteria,1N6XE@1224|Proteobacteria,42NBB@68525|delta/epsilon subdivisions,2WIMD@28221|Deltaproteobacteria,2MIEB@213118|Desulfobacterales	28221|Deltaproteobacteria	O	PFAM ResB family protein	-	-	-	ko:K07399	-	-	-	-	ko00000	-	-	-	ResB
k59_171812_1	1265505.ATUG01000003_gene350	6.37e-27	103.0	COG1225@1|root,COG1225@2|Bacteria,1N3ZR@1224|Proteobacteria,42TQK@68525|delta/epsilon subdivisions,2WQSX@28221|Deltaproteobacteria,2MKQ0@213118|Desulfobacterales	28221|Deltaproteobacteria	O	AhpC/TSA family	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
k59_171812_2	56780.SYN_00591	8.63e-41	140.0	COG1225@1|root,COG1225@2|Bacteria,1N9JS@1224|Proteobacteria,42R82@68525|delta/epsilon subdivisions,2WMVA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	1.11.1.15	ko:K03386	ko04214,map04214	-	-	-	ko00000,ko00001,ko01000,ko04147	-	-	-	AhpC-TSA
k59_111255_1	395963.Bind_0797	5.83e-12	66.6	COG0265@1|root,COG0265@2|Bacteria,1MURF@1224|Proteobacteria,2TUVW@28211|Alphaproteobacteria,3NC01@45404|Beijerinckiaceae	28211|Alphaproteobacteria	O	Domain present in PSD-95, Dlg, and ZO-1/2.	MA20_20705	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
k59_217121_1	598659.NAMH_0049	8.77e-11	62.8	COG1734@1|root,COG1734@2|Bacteria,1N8RB@1224|Proteobacteria,42W5H@68525|delta/epsilon subdivisions,2YT6W@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	DnaK suppressor protein	dksA	-	-	ko:K06204	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000,ko03009,ko03021	-	-	-	zf-dskA_traR
k59_217121_2	717231.Flexsi_0322	8.64e-54	171.0	COG1917@1|root,COG1917@2|Bacteria,2GGHG@200930|Deferribacteres	200930|Deferribacteres	S	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
k59_202312_1	1232437.KL661989_gene468	2.42e-146	424.0	COG1509@1|root,COG1509@2|Bacteria,1MUPJ@1224|Proteobacteria,42NCM@68525|delta/epsilon subdivisions,2WKN6@28221|Deltaproteobacteria,2MIXH@213118|Desulfobacterales	28221|Deltaproteobacteria	E	lysine 2,3-aminomutase	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_14
k59_209981_1	742159.HMPREF0004_3949	7.73e-71	225.0	COG2230@1|root,COG2230@2|Bacteria,1MUW5@1224|Proteobacteria,2VI5F@28216|Betaproteobacteria,3T6XM@506|Alcaligenaceae	28216|Betaproteobacteria	M	COG2230 Cyclopropane fatty acid synthase and related methyltransferases	-	-	2.1.1.79	ko:K00574	-	-	-	-	ko00000,ko01000	-	-	-	CMAS
k59_35565_1	1121441.AUCX01000018_gene1509	6.85e-90	271.0	COG0090@1|root,COG0090@2|Bacteria,1MVTD@1224|Proteobacteria,42MBV@68525|delta/epsilon subdivisions,2WIRE@28221|Deltaproteobacteria,2M8B7@213115|Desulfovibrionales	28221|Deltaproteobacteria	J	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity	rplB	GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02886	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L2,Ribosomal_L2_C
k59_80999_1	1283300.ATXB01000001_gene823	3.97e-28	119.0	COG1331@1|root,COG1331@2|Bacteria,1MUUT@1224|Proteobacteria,1RSQQ@1236|Gammaproteobacteria,1XE8M@135618|Methylococcales	135618|Methylococcales	O	Protein of unknown function, DUF255	-	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	DsbC,Thioredox_DsbH
k59_187397_2	394.NGR_c06900	4.25e-16	80.1	COG4186@1|root,COG4186@2|Bacteria,1N65E@1224|Proteobacteria,2UCBF@28211|Alphaproteobacteria,4BN3C@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	nucleotidyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_171819_1	1226994.AMZB01000118_gene3212	3.86e-13	68.6	COG4166@1|root,COG4166@2|Bacteria,1MUVU@1224|Proteobacteria,1RMA1@1236|Gammaproteobacteria,1YDUE@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	E	Bacterial extracellular solute-binding proteins, family 5 Middle	yejA	GO:0005575,GO:0005623,GO:0006810,GO:0006857,GO:0008150,GO:0015833,GO:0015893,GO:0030288,GO:0030313,GO:0031975,GO:0042221,GO:0042493,GO:0042597,GO:0042884,GO:0042886,GO:0042891,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0071702,GO:0071705	-	ko:K02035,ko:K13893	ko02010,ko02024,map02010,map02024	M00239,M00349	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.21,3.A.1.5.24	-	-	SBP_bac_5
k59_171819_2	485915.Dret_0179	5.2e-45	157.0	COG4174@1|root,COG4174@2|Bacteria,1MVKE@1224|Proteobacteria,43BKS@68525|delta/epsilon subdivisions,2X6YW@28221|Deltaproteobacteria,2M9NN@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K13894	ko02010,map02010	M00349	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.21,3.A.1.5.24	-	-	BPD_transp_1
k59_156856_2	1121459.AQXE01000013_gene2196	7.14e-10	65.5	COG5525@1|root,COG5525@2|Bacteria,1MVS3@1224|Proteobacteria,42MCU@68525|delta/epsilon subdivisions,2WJ3Q@28221|Deltaproteobacteria,2M93R@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Terminase	-	-	-	-	-	-	-	-	-	-	-	-	Terminase_GpA
k59_81001_1	1233951.IO90_06550	1.32e-06	48.9	COG1917@1|root,COG1917@2|Bacteria,4NSEB@976|Bacteroidetes,1I3XH@117743|Flavobacteriia,3HI9R@358033|Chryseobacterium	976|Bacteroidetes	S	AraC-like ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
k59_126663_1	96561.Dole_1534	4.01e-44	152.0	COG0596@1|root,COG0596@2|Bacteria,1QTTM@1224|Proteobacteria	1224|Proteobacteria	S	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6,Hydrolase_4
k59_103707_1	926569.ANT_26080	2.51e-12	72.8	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
k59_232932_1	589865.DaAHT2_0129	8.17e-47	159.0	COG0518@1|root,COG0518@2|Bacteria,1MUDH@1224|Proteobacteria,42RU1@68525|delta/epsilon subdivisions,2WNHA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	PFAM Glutamine amidotransferase class-I	-	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase
k59_111281_1	1462527.CCDM010000002_gene1022	9.33e-17	79.3	COG0584@1|root,COG0584@2|Bacteria,1V3W4@1239|Firmicutes,4HFNQ@91061|Bacilli	91061|Bacilli	C	glycerophosphoryl diester phosphodiesterase	glpQ1	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
k59_12999_2	1122194.AUHU01000006_gene476	2.17e-14	74.3	COG0330@1|root,COG0330@2|Bacteria,1MUM2@1224|Proteobacteria,1RPUE@1236|Gammaproteobacteria,466JG@72275|Alteromonadaceae	1236|Gammaproteobacteria	O	HflC and HflK could encode or regulate a protease	-	-	-	ko:K04088	-	M00742	-	-	ko00000,ko00002,ko01000	-	-	-	Band_7,HflK_N
k59_103714_1	1235788.C802_01760	5.02e-15	80.1	COG0745@1|root,COG3292@1|root,COG5002@1|root,COG0745@2|Bacteria,COG3292@2|Bacteria,COG5002@2|Bacteria,4NKPC@976|Bacteroidetes,2G0FQ@200643|Bacteroidia,4AV78@815|Bacteroidaceae	976|Bacteroidetes	T	COG COG3437 Response regulator containing a CheY-like receiver domain and an HD-GYP domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HTH_18,HisKA,Reg_prop,Response_reg,Y_Y_Y
k59_239596_1	335543.Sfum_4069	5.28e-169	483.0	COG0683@1|root,COG0683@2|Bacteria,1MXR4@1224|Proteobacteria,42MXX@68525|delta/epsilon subdivisions,2WKJM@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	PFAM Extracellular ligand-binding receptor	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
k59_126668_1	883.DvMF_1105	4.66e-19	82.8	2E20Q@1|root,32X8P@2|Bacteria,1NF7J@1224|Proteobacteria,42V60@68525|delta/epsilon subdivisions,2WRJ8@28221|Deltaproteobacteria,2MGN9@213115|Desulfovibrionales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_190929_1	1267535.KB906767_gene3841	2.14e-50	180.0	COG1640@1|root,COG1640@2|Bacteria,3Y6TQ@57723|Acidobacteria	57723|Acidobacteria	G	4-alpha-glucanotransferase	-	-	2.4.1.25	ko:K00705	ko00500,ko01100,map00500,map01100	-	R05196	RC00049	ko00000,ko00001,ko01000	-	GH77	-	Glyco_hydro_77
k59_145570_1	1089550.ATTH01000001_gene2320	3.36e-48	168.0	COG1972@1|root,COG1972@2|Bacteria,4NEYN@976|Bacteroidetes,1FIW1@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	F	Na+ dependent nucleoside transporter C-terminus	nupC	-	-	ko:K03317	-	-	-	-	ko00000	2.A.41	-	-	Gate,Nucleos_tra2_C,Nucleos_tra2_N
k59_39392_1	1265505.ATUG01000001_gene3881	8.44e-68	228.0	COG5009@1|root,COG5009@2|Bacteria,1MU5A@1224|Proteobacteria,42MJB@68525|delta/epsilon subdivisions,2WIXF@28221|Deltaproteobacteria,2MI9W@213118|Desulfobacterales	28221|Deltaproteobacteria	M	TIGRFAM penicillin-binding protein, 1A family	mrcA	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	iAF987.Gmet_0354	PCB_OB,Transgly,Transpeptidase
k59_54528_1	1349820.M707_22695	1.02e-82	251.0	COG1961@1|root,COG1961@2|Bacteria,2HSUX@201174|Actinobacteria,1WCJY@1268|Micrococcaceae	201174|Actinobacteria	L	Resolvase, N terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_7,Resolvase
k59_84787_1	1121403.AUCV01000001_gene676	3.21e-60	197.0	COG1270@1|root,COG1270@2|Bacteria,1MURM@1224|Proteobacteria,42PDX@68525|delta/epsilon subdivisions,2WKH4@28221|Deltaproteobacteria,2MIRQ@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group	cobD	-	6.3.1.10	ko:K02227	ko00860,ko01100,map00860,map01100	M00122	R06529,R07302	RC00090,RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	CobD_Cbib
k59_168129_1	1121430.JMLG01000033_gene1349	0.00047	39.7	COG1841@1|root,COG1841@2|Bacteria,1VEG4@1239|Firmicutes,24QKC@186801|Clostridia,2633H@186807|Peptococcaceae	186801|Clostridia	J	Ribosomal protein L30p/L7e	rpmD	-	-	ko:K02907	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L30
k59_168129_2	933262.AXAM01000052_gene2008	2.63e-65	202.0	COG0200@1|root,COG0200@2|Bacteria,1RDC8@1224|Proteobacteria,42SRC@68525|delta/epsilon subdivisions,2WQQ4@28221|Deltaproteobacteria,2MK6Y@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Binds to the 23S rRNA	rplO	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02876	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27A
k59_168129_3	1121405.dsmv_3570	5.99e-174	495.0	COG0201@1|root,COG0201@2|Bacteria,1MVU7@1224|Proteobacteria,42MGM@68525|delta/epsilon subdivisions,2WIZ7@28221|Deltaproteobacteria,2MHM9@213118|Desulfobacterales	28221|Deltaproteobacteria	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	-	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
k59_228935_1	1158318.ATXC01000001_gene666	3.82e-46	160.0	COG1079@1|root,COG1079@2|Bacteria	2|Bacteria	S	Belongs to the binding-protein-dependent transport system permease family	rbsC-2	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
k59_24589_1	167542.P9515_14881	1.02e-15	77.4	COG0344@1|root,COG0344@2|Bacteria,1G3HV@1117|Cyanobacteria,1MMDI@1212|Prochloraceae	1117|Cyanobacteria	I	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP	plsY	-	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	G3P_acyltransf
k59_77894_1	96561.Dole_2294	8.81e-55	186.0	COG0446@1|root,COG0446@2|Bacteria,1NR3M@1224|Proteobacteria,42N3G@68525|delta/epsilon subdivisions,2WIS9@28221|Deltaproteobacteria,2MI5A@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Pyr_redox_dim
k59_9611_1	1232437.KL662031_gene2526	3.03e-98	307.0	COG1148@1|root,COG1148@2|Bacteria,1QUM4@1224|Proteobacteria,42MPP@68525|delta/epsilon subdivisions,2WJ3U@28221|Deltaproteobacteria,2MMQ1@213118|Desulfobacterales	28221|Deltaproteobacteria	C	NAD(P)-binding Rossmann-like domain	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_6,Pyr_redox_2
k59_100602_2	96561.Dole_2959	2.88e-18	82.8	2CFUQ@1|root,2ZC1I@2|Bacteria,1RBHI@1224|Proteobacteria,42QR4@68525|delta/epsilon subdivisions,2WMXI@28221|Deltaproteobacteria,2MJQJ@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_100606_1	1173027.Mic7113_5927	6.05e-55	189.0	COG5002@1|root,COG5002@2|Bacteria,1G4FM@1117|Cyanobacteria,1HH4Y@1150|Oscillatoriales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,PAS_4
k59_168602_1	439235.Dalk_4801	2.99e-140	405.0	COG3385@1|root,COG3385@2|Bacteria,1PMXF@1224|Proteobacteria,43B8Z@68525|delta/epsilon subdivisions,2X6NB@28221|Deltaproteobacteria,2MPI8@213118|Desulfobacterales	1224|Proteobacteria	L	PFAM transposase IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DUF4372
k59_47499_1	314270.RB2083_2577	9.78e-92	284.0	COG2984@1|root,COG2984@2|Bacteria,1MW5D@1224|Proteobacteria,2U2B6@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	ABC transporter substrate binding protein	-	-	-	ko:K01989	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_sub_bind
k59_146008_1	1122135.KB893137_gene1234	2.68e-102	305.0	COG0559@1|root,COG0559@2|Bacteria,1MU25@1224|Proteobacteria,2U4X3@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Branched-chain amino acid transport system / permease component	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
k59_191434_1	1304885.AUEY01000003_gene545	2.07e-41	152.0	COG0532@1|root,COG0532@2|Bacteria,1MV26@1224|Proteobacteria,42M5Q@68525|delta/epsilon subdivisions,2WIIX@28221|Deltaproteobacteria,2MIGT@213118|Desulfobacterales	28221|Deltaproteobacteria	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,IF-2,IF2_N
k59_191434_2	1121405.dsmv_2733	1.32e-19	81.6	COG1550@1|root,COG1550@2|Bacteria,1N2H7@1224|Proteobacteria,42UCZ@68525|delta/epsilon subdivisions,2WR50@28221|Deltaproteobacteria,2MKM4@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF503)	-	-	-	ko:K09764	-	-	-	-	ko00000	-	-	-	DUF503
k59_183820_1	1163617.SCD_n00291	4.34e-20	85.1	2E7KC@1|root,3025Q@2|Bacteria,1PUPZ@1224|Proteobacteria,2VXH0@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_191435_1	1032480.MLP_04170	3.55e-09	58.5	COG1454@1|root,COG1454@2|Bacteria,2IDI8@201174|Actinobacteria,4DWNA@85009|Propionibacteriales	201174|Actinobacteria	C	Iron-containing alcohol dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Fe-ADH
k59_183825_2	880072.Desac_0395	1.43e-19	83.6	COG0589@1|root,COG0589@2|Bacteria	2|Bacteria	T	AMP binding	usp-3	-	-	-	-	-	-	-	-	-	-	-	Usp
k59_92836_1	1185652.USDA257_c20940	0.000402	44.3	COG5642@1|root,COG5642@2|Bacteria,1RK9F@1224|Proteobacteria,2UA8G@28211|Alphaproteobacteria,4BEQN@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Protein of unknown function (DUF2384)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2384
k59_214140_1	177437.HRM2_07810	6.14e-27	105.0	COG0589@1|root,COG0589@2|Bacteria	2|Bacteria	T	AMP binding	-	-	-	-	-	-	-	-	-	-	-	-	Usp
k59_176319_1	867903.ThesuDRAFT_01213	1.42e-56	189.0	COG0114@1|root,COG0114@2|Bacteria,1UHPH@1239|Firmicutes,25F3I@186801|Clostridia,3WCCI@538999|Clostridiales incertae sedis	186801|Clostridia	C	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate	fumC	-	4.2.1.2	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	M00009,M00011,M00173,M00376	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	FumaraseC_C,Lyase_1
k59_1847_1	886293.Sinac_0266	0.000485	43.9	2ETZI@1|root,33MGP@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1847_2	348824.LPU83_2004	2.1e-32	117.0	COG0137@1|root,COG0137@2|Bacteria	2|Bacteria	E	argininosuccinate synthase activity	argG	GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iJN678.argG,iSB619.SA_RS04675	Arginosuc_synth
k59_1847_4	305700.B447_18053	2.28e-11	68.9	COG4974@1|root,COG4974@2|Bacteria,1R6F9@1224|Proteobacteria,2W3AX@28216|Betaproteobacteria	28216|Betaproteobacteria	L	PFAM integrase family protein	-	-	-	ko:K07357,ko:K07358	-	-	-	-	ko00000	-	-	-	Phage_integrase
k59_24607_1	1121918.ARWE01000001_gene3481	1.21e-09	59.7	COG5266@1|root,COG5266@2|Bacteria,1PVKN@1224|Proteobacteria,42PYV@68525|delta/epsilon subdivisions,2WK42@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	PFAM Nickel transport complex, NikM subunit, transmembrane	-	-	-	ko:K02009	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18	-	-	DUF4198
k59_24607_2	335543.Sfum_2525	5.64e-56	188.0	COG0568@1|root,COG0568@2|Bacteria,1MXGX@1224|Proteobacteria,42PIS@68525|delta/epsilon subdivisions,2WKSS@28221|Deltaproteobacteria,2MQYD@213462|Syntrophobacterales	28221|Deltaproteobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	-	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
k59_62721_1	1187851.A33M_3524	1.08e-68	222.0	COG4177@1|root,COG4177@2|Bacteria,1MWP3@1224|Proteobacteria,2VEXG@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
k59_62721_2	909613.UO65_4167	1.04e-06	52.8	COG1131@1|root,COG2936@1|root,COG1131@2|Bacteria,COG2936@2|Bacteria,2GN8P@201174|Actinobacteria,4DZ82@85010|Pseudonocardiales	201174|Actinobacteria	V	ABC-type multidrug transport system, ATPase component	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,PepX_C,Peptidase_S15
k59_214152_1	1125863.JAFN01000001_gene1966	2.52e-88	270.0	COG0823@1|root,COG0823@2|Bacteria,1QW3I@1224|Proteobacteria	1224|Proteobacteria	U	Beta Propeller	-	-	-	-	-	-	-	-	-	-	-	-	PD40
k59_47522_1	368407.Memar_0463	5.18e-48	169.0	COG1180@1|root,arCOG00946@2157|Archaea	2157|Archaea	C	PFAM Radical SAM domain protein	-	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Radical_SAM
k59_123343_1	933262.AXAM01000017_gene3145	4.27e-57	201.0	COG0493@1|root,COG1148@1|root,COG0493@2|Bacteria,COG1148@2|Bacteria,1QUM4@1224|Proteobacteria,42MPP@68525|delta/epsilon subdivisions,2WJ3U@28221|Deltaproteobacteria,2MIA4@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_20,Fer4_7,Pyr_redox_2
k59_24618_1	998088.B565_2943	7.99e-31	119.0	COG0530@1|root,COG0530@2|Bacteria,1MU3R@1224|Proteobacteria,1RMRD@1236|Gammaproteobacteria,1Y40H@135624|Aeromonadales	135624|Aeromonadales	P	COG0530 Ca2 Na antiporter	-	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
k59_161315_2	335543.Sfum_3397	2.45e-83	254.0	COG0411@1|root,COG0411@2|Bacteria,1MUFT@1224|Proteobacteria,42YMD@68525|delta/epsilon subdivisions,2WUG7@28221|Deltaproteobacteria,2MRMN@213462|Syntrophobacterales	28221|Deltaproteobacteria	E	Branched-chain amino acid ATP-binding cassette transporter	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
k59_70148_1	999425.HMPREF9186_00735	6.29e-82	252.0	COG0410@1|root,COG0410@2|Bacteria,1TPW4@1239|Firmicutes,4HABJ@91061|Bacilli	91061|Bacilli	E	COG0410 ABC-type branched-chain amino acid transport systems, ATPase component	livF	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
k59_237050_1	243232.MJ_1384	3.07e-21	92.8	COG0778@1|root,arCOG00288@2157|Archaea,2XXW2@28890|Euryarchaeota	28890|Euryarchaeota	C	Nitroreductase	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
k59_237050_2	1380390.JIAT01000010_gene3616	3.35e-06	48.5	COG1250@1|root,COG1250@2|Bacteria,2GJBM@201174|Actinobacteria	201174|Actinobacteria	I	3-hydroxyacyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	3HCDH,3HCDH_N
k59_85243_1	335543.Sfum_3063	5.61e-107	322.0	COG0793@1|root,COG0793@2|Bacteria,1MU39@1224|Proteobacteria,42MHD@68525|delta/epsilon subdivisions,2WJKC@28221|Deltaproteobacteria,2MQ40@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	PDZ domain (Also known as DHR or GLGF)	ctpA	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_S41
k59_39952_1	555779.Dthio_PD1799	6.69e-59	206.0	COG1924@1|root,COG3580@1|root,COG1924@2|Bacteria,COG3580@2|Bacteria,1PKG6@1224|Proteobacteria,42MY4@68525|delta/epsilon subdivisions,2WJFI@28221|Deltaproteobacteria,2M8T9@213115|Desulfovibrionales	28221|Deltaproteobacteria	I	ATPase BadF BadG BcrA BcrD type	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG,DUF2229
k59_221892_1	247634.GPB2148_1961	7.75e-89	279.0	COG1524@1|root,COG1524@2|Bacteria,1R5V5@1224|Proteobacteria,1S06C@1236|Gammaproteobacteria,1J9AQ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	proteins of the AP superfamily	pafA	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
k59_183844_1	313598.MED152_08530	3.98e-06	52.4	COG0841@1|root,COG0841@2|Bacteria,4NDZG@976|Bacteroidetes,1HX2H@117743|Flavobacteriia,3VWBA@52959|Polaribacter	976|Bacteroidetes	V	MMPL family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_55183_1	1220534.B655_0941	1.69e-67	219.0	COG1032@1|root,arCOG01356@2157|Archaea	2157|Archaea	C	SMART Elongator protein 3 MiaB NifB	-	-	1.21.98.3	ko:K04034	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R06268,R06269,R06270	RC00741,RC01491,RC01492	ko00000,ko00001,ko01000	-	-	-	B12-binding,Radical_SAM
k59_229392_1	935948.KE386495_gene1554	3.4e-10	60.8	COG0209@1|root,COG0209@2|Bacteria,1TPFH@1239|Firmicutes,249EN@186801|Clostridia,42F6G@68295|Thermoanaerobacterales	186801|Clostridia	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	nrdJ	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Intein_splicing,LAGLIDADG_3,Ribonuc_red_2_N,Ribonuc_red_lgC,Ribonuc_red_lgN,TSCPD
k59_229392_2	1121428.DESHY_110154___1	0.000958	41.2	COG0540@1|root,COG0540@2|Bacteria,1TQ96@1239|Firmicutes,2496D@186801|Clostridia,260AV@186807|Peptococcaceae	186801|Clostridia	F	Belongs to the ATCase OTCase family	pyrB	-	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
k59_1887_1	338966.Ppro_2232	1.98e-32	133.0	COG3605@1|root,COG3605@2|Bacteria,1QTTV@1224|Proteobacteria,42PST@68525|delta/epsilon subdivisions,2WJ3A@28221|Deltaproteobacteria,43UG1@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	TIGRFAM phosphoenolpyruvate-protein phosphotransferase	ptsP	-	2.7.3.9	ko:K08484	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	-	-	-	GAF_2,PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C
k59_85255_1	933262.AXAM01000016_gene189	6.81e-83	251.0	COG1277@1|root,COG1277@2|Bacteria,1NZZ9@1224|Proteobacteria,42SH9@68525|delta/epsilon subdivisions,2WPWW@28221|Deltaproteobacteria,2MIHA@213118|Desulfobacterales	28221|Deltaproteobacteria	N	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC2_membrane_3,ABC_transp_aux
k59_176347_1	1297742.A176_00379	1.32e-07	55.5	COG5662@1|root,COG5662@2|Bacteria	2|Bacteria	K	AntiSigma factor	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
k59_176347_2	1120959.ATXF01000004_gene3027	4.33e-14	72.0	COG1595@1|root,COG1595@2|Bacteria,2GJ02@201174|Actinobacteria,4FKHT@85023|Microbacteriaceae	201174|Actinobacteria	K	Sigma-70, region 4	sigH	GO:0005575,GO:0005618,GO:0005623,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0033554,GO:0034605,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0051409,GO:0051716,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1903506,GO:2000112,GO:2001141	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
k59_191457_1	335543.Sfum_0797	6.2e-92	293.0	COG0633@1|root,COG3894@1|root,COG0633@2|Bacteria,COG3894@2|Bacteria,1MV6C@1224|Proteobacteria,42MF5@68525|delta/epsilon subdivisions,2WKC6@28221|Deltaproteobacteria,2MQU1@213462|Syntrophobacterales	68525|delta/epsilon subdivisions	C	PFAM 2Fe-2S iron-sulfur cluster binding domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4445,Fer2
k59_191457_2	1132442.KB889753_gene83	2.34e-14	75.5	COG0683@1|root,COG3284@1|root,COG0683@2|Bacteria,COG3284@2|Bacteria,1VHQN@1239|Firmicutes,4HUF7@91061|Bacilli,1ZS1R@1386|Bacillus	91061|Bacilli	KQ	COG3284 Transcriptional activator of acetoin glycerol metabolism	-	-	-	ko:K21405	-	-	-	-	ko00000,ko03000	-	-	-	GAF,HTH_8,Peripla_BP_5,Sigma54_activat
k59_70172_1	909663.KI867150_gene1523	1.41e-09	67.8	COG4262@1|root,COG4262@2|Bacteria,1QUPY@1224|Proteobacteria	1224|Proteobacteria	S	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	-	-	-	-	-	-	-	-	-	-	-	-	Spermine_synth
k59_176354_1	933262.AXAM01000030_gene804	3.3e-83	254.0	COG2159@1|root,COG2159@2|Bacteria,1Q0A4@1224|Proteobacteria,42Q9N@68525|delta/epsilon subdivisions,2WJTE@28221|Deltaproteobacteria,2MI7C@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Amidohydrolase	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
k59_71919_1	335543.Sfum_2418	9.55e-49	171.0	COG0308@1|root,COG0308@2|Bacteria,1NJK3@1224|Proteobacteria,42Y4Q@68525|delta/epsilon subdivisions,2WTET@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	aminopeptidase N	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_MA_2
k59_57485_1	1121918.ARWE01000001_gene2811	2.1e-97	296.0	COG0683@1|root,COG0683@2|Bacteria,1MWNB@1224|Proteobacteria,42TEX@68525|delta/epsilon subdivisions,2WPG8@28221|Deltaproteobacteria,43T5H@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	Periplasmic binding protein domain	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
k59_80115_1	933262.AXAM01000053_gene2709	5.66e-158	462.0	COG1884@1|root,COG2185@1|root,COG1884@2|Bacteria,COG2185@2|Bacteria,1MUXX@1224|Proteobacteria,42P03@68525|delta/epsilon subdivisions,2WIPY@28221|Deltaproteobacteria,2MICJ@213118|Desulfobacterales	28221|Deltaproteobacteria	I	TIGRFAM methylmalonyl-CoA mutase, large subunit	-	-	5.4.99.2	ko:K01847	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,MM_CoA_mutase
k59_231926_1	1137268.AZXF01000019_gene428	1.31e-27	113.0	COG0500@1|root,COG0500@2|Bacteria,2I2Y4@201174|Actinobacteria,4EGRS@85012|Streptosporangiales	201174|Actinobacteria	Q	Dimerisation domain	-	-	2.1.1.302	ko:K21377	-	-	-	-	ko00000,ko01000	-	-	-	Dimerisation2,Methyltransf_2
k59_26494_1	1499967.BAYZ01000073_gene2046	4.96e-70	224.0	COG0436@1|root,COG0436@2|Bacteria	2|Bacteria	E	Aminotransferase	-	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
k59_3441_1	177437.HRM2_30650	3.52e-35	129.0	COG0330@1|root,COG0330@2|Bacteria,1MV7R@1224|Proteobacteria,42N2V@68525|delta/epsilon subdivisions,2WIPS@28221|Deltaproteobacteria,2MIPC@213118|Desulfobacterales	28221|Deltaproteobacteria	O	HflC and HflK could regulate a protease	hflC	-	-	ko:K04087	-	M00742	-	-	ko00000,ko00002,ko01000	-	-	-	Band_7
k59_3441_2	96561.Dole_0545	2.26e-26	105.0	COG0330@1|root,COG0330@2|Bacteria,1MUM2@1224|Proteobacteria,42NUT@68525|delta/epsilon subdivisions,2WKQX@28221|Deltaproteobacteria,2MI5I@213118|Desulfobacterales	28221|Deltaproteobacteria	O	HflC and HflK could encode or regulate a protease	hflK	-	-	ko:K04088	-	M00742	-	-	ko00000,ko00002,ko01000	-	-	-	Band_7
k59_102855_1	933262.AXAM01000107_gene1504	5.75e-38	145.0	COG0493@1|root,COG2878@1|root,COG0493@2|Bacteria,COG2878@2|Bacteria,1NZIR@1224|Proteobacteria,42MPF@68525|delta/epsilon subdivisions,2X5BJ@28221|Deltaproteobacteria,2MISB@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Putative Fe-S cluster	-	-	-	-	-	-	-	-	-	-	-	-	FeS,Fer4,Fer4_20,Fer4_9,Pyr_redox_2
k59_193236_1	1365176.N186_09710	1.21e-13	76.6	COG1042@1|root,arCOG01340@2157|Archaea,2XPR9@28889|Crenarchaeota	28889|Crenarchaeota	C	PFAM CoA-binding domain protein	-	-	6.2.1.13	ko:K01905	ko00010,ko00620,ko00640,ko01100,ko01120,map00010,map00620,map00640,map01100,map01120	-	R00229,R00920	RC00004,RC00012,RC00014	ko00000,ko00001,ko01000,ko01004	-	-	-	CoA_binding_2,Succ_CoA_lig
k59_201373_1	386456.JQKN01000011_gene786	5e-118	350.0	COG1541@1|root,arCOG02622@2157|Archaea,2XVU6@28890|Euryarchaeota	28890|Euryarchaeota	H	TIGRFAM Coenzyme F390 synthetase	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding
k59_95168_1	459349.CLOAM1546	6.03e-34	132.0	COG0457@1|root,COG3604@1|root,COG0457@2|Bacteria,COG3604@2|Bacteria	2|Bacteria	KT	transcription factor binding	nifA	-	-	ko:K02584,ko:K11914	ko02020,map02020	-	-	-	ko00000,ko00001,ko02044,ko03000	-	-	-	GAF,GAF_2,HTH_8,Sigma54_activat
k59_178057_1	1121405.dsmv_3712	1.24e-121	362.0	28I62@1|root,2Z896@2|Bacteria,1MWB8@1224|Proteobacteria,42P7E@68525|delta/epsilon subdivisions,2WKM1@28221|Deltaproteobacteria,2MIBX@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_102858_1	765911.Thivi_4300	1.78e-30	122.0	COG5659@1|root,COG5659@2|Bacteria,1MXSV@1224|Proteobacteria,1SBWP@1236|Gammaproteobacteria,1WZ1F@135613|Chromatiales	1236|Gammaproteobacteria	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_5,DDE_Tnp_1
k59_80128_1	439235.Dalk_1689	7.89e-45	165.0	COG2202@1|root,COG2204@1|root,COG4191@1|root,COG2202@2|Bacteria,COG2204@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MFW@68525|delta/epsilon subdivisions,2WKMP@28221|Deltaproteobacteria,2MI6S@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_3,Response_reg
k59_12135_1	92637.XP_007808819.1	2.97e-08	60.5	28NFY@1|root,2QV1J@2759|Eukaryota,39S95@33154|Opisthokonta,3P178@4751|Fungi,3QV5D@4890|Ascomycota,217Y5@147550|Sordariomycetes,3TFHT@5125|Hypocreales,3G57Q@34397|Clavicipitaceae	4751|Fungi	G	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
k59_26498_1	926569.ANT_04990	3.21e-31	114.0	COG1662@1|root,COG1662@2|Bacteria	2|Bacteria	L	PFAM IS1 transposase	-	-	-	ko:K07480	-	-	-	-	ko00000	-	-	-	DDE_Tnp_IS1
k59_26498_2	926569.ANT_04980	1.15e-32	117.0	COG3677@1|root,COG3677@2|Bacteria,2G9MB@200795|Chloroflexi	200795|Chloroflexi	L	Putative ATPase subunit of terminase (gpP-like)	-	-	-	-	-	-	-	-	-	-	-	-	HTH_23
k59_231946_1	269796.Rru_A0109	2.33e-31	128.0	COG1450@1|root,COG1450@2|Bacteria,1MUUA@1224|Proteobacteria,2TT8A@28211|Alphaproteobacteria,2JQ61@204441|Rhodospirillales	204441|Rhodospirillales	NU	Bacterial type II and III secretion system protein	-	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	Secretin,Secretin_N
k59_64530_1	630626.EBL_c21750	6.51e-44	157.0	28J9D@1|root,2Z94E@2|Bacteria,1QE0C@1224|Proteobacteria,1RZ22@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	P22 coat protein - gene protein 5	-	-	-	-	-	-	-	-	-	-	-	-	P22_CoatProtein
k59_155979_1	247633.GP2143_10322	1.25e-41	155.0	COG3419@1|root,COG3419@2|Bacteria,1NUAV@1224|Proteobacteria,1RPV3@1236|Gammaproteobacteria	1236|Gammaproteobacteria	NU	Tfp pilus assembly protein tip-associated adhesin PilY1	-	-	-	ko:K02674	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	Neisseria_PilC
k59_186581_1	1265505.ATUG01000003_gene346	4.37e-39	135.0	COG0243@1|root,COG0243@2|Bacteria,1MWPS@1224|Proteobacteria,42QIW@68525|delta/epsilon subdivisions,2WJPY@28221|Deltaproteobacteria,2MJP1@213118|Desulfobacterales	28221|Deltaproteobacteria	C	TAT (twin-arginine translocation) pathway signal sequence	-	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Molybdop_Fe4S4,Molybdopterin,TAT_signal
k59_26505_1	237368.SCABRO_02052	9.84e-26	110.0	COG2203@1|root,COG4191@1|root,COG2203@2|Bacteria,COG4191@2|Bacteria,2J3WG@203682|Planctomycetes	2|Bacteria	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	-	ko:K03406,ko:K21009	ko02020,ko02025,ko02030,map02020,map02025,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	GAF,GAF_2,HATPase_c,HWE_HK,HisKA,MCPsignal,PAS,PAS_3,PAS_4,PAS_9,Response_reg
k59_216243_1	985255.APHJ01000031_gene2834	9.77e-14	76.6	COG4974@1|root,COG4974@2|Bacteria,4NGE1@976|Bacteroidetes,1HY1D@117743|Flavobacteriia,2P5FE@244698|Gillisia	976|Bacteroidetes	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
k59_102866_1	1120970.AUBZ01000002_gene732	1.14e-14	74.3	COG1028@1|root,COG1028@2|Bacteria,1N907@1224|Proteobacteria,1SMBC@1236|Gammaproteobacteria,46ATW@72275|Alteromonadaceae	1236|Gammaproteobacteria	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
k59_102866_2	177437.HRM2_42100	0.000872	42.7	COG3243@1|root,COG3243@2|Bacteria,1MU68@1224|Proteobacteria,42MW8@68525|delta/epsilon subdivisions,2WKI6@28221|Deltaproteobacteria,2MIK1@213118|Desulfobacterales	28221|Deltaproteobacteria	I	Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus	phaC	-	-	ko:K03821	ko00650,map00650	-	R04254	RC00004	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1
k59_209184_1	1229909.NSED_03045	6.54e-07	50.8	COG1243@1|root,arCOG01361@2157|Archaea,41S9N@651137|Thaumarchaeota	651137|Thaumarchaeota	K	Histone acetyltransferase	-	-	2.3.1.48	ko:K07739	-	-	-	-	ko00000,ko01000,ko03016,ko03036	-	-	-	Acetyltransf_1,Radical_SAM,Radical_SAM_C
k59_209184_2	591019.Shell_1195	3.71e-32	125.0	COG0252@1|root,arCOG01924@2157|Archaea,2XPTP@28889|Crenarchaeota	28889|Crenarchaeota	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate	gatD	-	6.3.5.7	ko:K09482	ko00970,ko01100,map00970,map01100	-	R03905	RC00010	ko00000,ko00001,ko01000	-	-	-	Asparaginase
k59_201401_1	335543.Sfum_2640	3.47e-47	162.0	29QS6@1|root,30BS1@2|Bacteria,1REGY@1224|Proteobacteria,42RJ2@68525|delta/epsilon subdivisions,2WNQQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_163069_2	1429046.RR21198_0290	1.46e-43	159.0	COG3497@1|root,COG3497@2|Bacteria,2GMJA@201174|Actinobacteria,4G5W9@85025|Nocardiaceae	201174|Actinobacteria	S	Phage tail sheath C-terminal domain	-	-	-	ko:K06907	-	-	-	-	ko00000	-	-	-	Phage_sheath_1,Phage_sheath_1C
k59_140873_1	1173264.KI913949_gene498	3.8e-138	404.0	COG3328@1|root,COG3328@2|Bacteria,1G3YG@1117|Cyanobacteria,1HE7N@1150|Oscillatoriales	1117|Cyanobacteria	L	Transposase, Mutator family	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_mut
k59_49457_1	690850.Desaf_2573	4.59e-13	67.8	COG3119@1|root,COG3119@2|Bacteria,1MUJH@1224|Proteobacteria,42Q8I@68525|delta/epsilon subdivisions,2X5IX@28221|Deltaproteobacteria,2MA7R@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	Sulfatase	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase,Sulfatase_C
k59_49457_2	452652.KSE_34290	3.65e-20	89.7	COG5361@1|root,COG5361@2|Bacteria,2GRDZ@201174|Actinobacteria,2M1BU@2063|Kitasatospora	201174|Actinobacteria	S	Protein of unknown function (DUF1214)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1214,DUF1254
k59_216250_1	706587.Desti_1834	2.53e-56	194.0	COG0145@1|root,COG0145@2|Bacteria,1MU2Y@1224|Proteobacteria,42NFP@68525|delta/epsilon subdivisions,2WK64@28221|Deltaproteobacteria,2MQZU@213462|Syntrophobacterales	28221|Deltaproteobacteria	EQ	Hydantoinase/oxoprolinase N-terminal region	hyuA	-	3.5.2.14	ko:K01473	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydant_A_N,Hydantoinase_A
k59_95204_1	1121405.dsmv_3041	2.51e-96	298.0	COG0441@1|root,COG0441@2|Bacteria,1MUP2@1224|Proteobacteria,42M20@68525|delta/epsilon subdivisions,2WJ2N@28221|Deltaproteobacteria,2MI0Z@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD
k59_178073_1	768671.ThimaDRAFT_4269	7.69e-50	173.0	COG0702@1|root,COG0702@2|Bacteria,1MW54@1224|Proteobacteria,1RY2H@1236|Gammaproteobacteria,1WX0H@135613|Chromatiales	135613|Chromatiales	GM	epimerase dehydratase	-	-	1.6.5.3,1.6.99.3	ko:K00329,ko:K00356	ko00190,map00190	-	R11945	RC00061	ko00000,ko00001,ko01000	-	-	-	NAD_binding_10
k59_178073_2	1132855.KB913035_gene2131	7.9e-29	110.0	COG1994@1|root,COG1994@2|Bacteria,1NSFF@1224|Proteobacteria,2VHAM@28216|Betaproteobacteria,2KKUP@206350|Nitrosomonadales	206350|Nitrosomonadales	S	Peptidase family M50	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50
k59_19052_1	96561.Dole_2880	2.08e-75	229.0	COG4871@1|root,COG4871@2|Bacteria,1RF0E@1224|Proteobacteria,42RKU@68525|delta/epsilon subdivisions,2WNHT@28221|Deltaproteobacteria,2MK4I@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Putative Fe-S cluster	-	-	-	-	-	-	-	-	-	-	-	-	FeS
k59_19052_2	96561.Dole_2878	5.31e-38	128.0	COG0526@1|root,COG0526@2|Bacteria,1N728@1224|Proteobacteria,42V0C@68525|delta/epsilon subdivisions,2WRJR@28221|Deltaproteobacteria,2MKY2@213118|Desulfobacterales	28221|Deltaproteobacteria	CO	redox-active disulfide protein 2	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_3
k59_19052_3	177437.HRM2_48210	6.53e-13	67.8	COG0701@1|root,COG0701@2|Bacteria,1MUN8@1224|Proteobacteria,42N6E@68525|delta/epsilon subdivisions,2WJXG@28221|Deltaproteobacteria,2MJ1N@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Predicted permease	-	-	-	ko:K07089	-	-	-	-	ko00000	-	-	-	ArsP_1
k59_72570_1	47716.JOFH01000015_gene5721	5.55e-15	79.3	COG1804@1|root,COG1804@2|Bacteria,2GIU7@201174|Actinobacteria	201174|Actinobacteria	C	L-carnitine dehydratase bile acid-inducible protein F	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
k59_201409_1	794903.OPIT5_30520	2.19e-43	159.0	COG0012@1|root,COG0012@2|Bacteria,46UY8@74201|Verrucomicrobia	74201|Verrucomicrobia	J	GTP binding	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_34718_1	411490.ANACAC_03326	1.91e-61	195.0	COG0245@1|root,COG0245@2|Bacteria,1V3P0@1239|Firmicutes,24HCM@186801|Clostridia	186801|Clostridia	I	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)	ispF	-	2.7.7.60,4.6.1.12	ko:K01770,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633,R05637	RC00002,RC01440	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD,YgbB
k59_110455_1	526222.Desal_3047	5.71e-70	238.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2WJN5@28221|Deltaproteobacteria,2MG2T@213115|Desulfovibrionales	28221|Deltaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_19056_2	1167006.UWK_01764	6.95e-51	171.0	COG2122@1|root,COG2122@2|Bacteria,1MV9Z@1224|Proteobacteria,42PMZ@68525|delta/epsilon subdivisions,2WMF7@28221|Deltaproteobacteria,2MJ13@213118|Desulfobacterales	28221|Deltaproteobacteria	S	PFAM ApbE family	-	-	-	ko:K09740	-	-	-	-	ko00000	-	-	-	-
k59_72580_1	335543.Sfum_3485	6.19e-57	188.0	COG0448@1|root,COG0448@2|Bacteria,1MVTC@1224|Proteobacteria,42NGK@68525|delta/epsilon subdivisions,2WM29@28221|Deltaproteobacteria,2MQBW@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans	glgC	-	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2768	NTP_transferase
k59_216263_1	1265505.ATUG01000001_gene3881	5.39e-99	313.0	COG5009@1|root,COG5009@2|Bacteria,1MU5A@1224|Proteobacteria,42MJB@68525|delta/epsilon subdivisions,2WIXF@28221|Deltaproteobacteria,2MI9W@213118|Desulfobacterales	28221|Deltaproteobacteria	M	TIGRFAM penicillin-binding protein, 1A family	mrcA	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	iAF987.Gmet_0354	PCB_OB,Transgly,Transpeptidase
k59_80174_1	1536774.H70357_28975	8.1e-27	112.0	COG0168@1|root,COG0168@2|Bacteria,1TQ4S@1239|Firmicutes,4H9ME@91061|Bacilli,26QDR@186822|Paenibacillaceae	91061|Bacilli	P	ATP synthase subunit J	ktrB3	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
k59_201422_1	644282.Deba_1503	7.36e-59	193.0	COG0500@1|root,COG2226@2|Bacteria,1PCH2@1224|Proteobacteria,42M58@68525|delta/epsilon subdivisions,2WK5Z@28221|Deltaproteobacteria	28221|Deltaproteobacteria	OQ	PFAM Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
k59_201422_2	28377.ENSACAP00000002887	3.16e-37	139.0	COG0415@1|root,KOG0133@2759|Eukaryota,38EHG@33154|Opisthokonta,3BH22@33208|Metazoa,3CX79@33213|Bilateria,485IS@7711|Chordata,49865@7742|Vertebrata	33208|Metazoa	LT	DNA photolyase	phr	GO:0000719,GO:0003674,GO:0003824,GO:0003904,GO:0003913,GO:0006139,GO:0006259,GO:0006281,GO:0006290,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016830,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360	4.1.99.3	ko:K01669	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_photolyase
k59_49470_1	1121405.dsmv_1966	2.78e-23	96.3	COG3383@1|root,COG3383@2|Bacteria	2|Bacteria	C	formate dehydrogenase (NAD+) activity	-	-	1.17.1.9,1.6.5.3	ko:K00123,ko:K00336	ko00190,ko00630,ko00680,ko01100,ko01120,ko01200,map00190,map00630,map00680,map01100,map01120,map01200	M00144	R00519,R11945	RC00061,RC02796	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,Fer4,Fer4_21,NADH-G_4Fe-4S_3
k59_171113_2	1400524.KL370779_gene628	3.57e-09	63.2	COG0451@1|root,COG0451@2|Bacteria	2|Bacteria	GM	ADP-glyceromanno-heptose 6-epimerase activity	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
k59_72594_1	439481.Aboo_1435	4.27e-39	144.0	COG0174@1|root,arCOG01909@2157|Archaea,2XSYS@28890|Euryarchaeota,3F33N@33867|unclassified Euryarchaeota	28890|Euryarchaeota	E	TIGRFAM glutamine synthetase, type I	glnA	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
k59_95224_1	1121405.dsmv_3030	3.46e-93	280.0	COG0604@1|root,COG0604@2|Bacteria,1MWBD@1224|Proteobacteria,42PQH@68525|delta/epsilon subdivisions,2WM5W@28221|Deltaproteobacteria,2MN4X@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Zinc-binding dehydrogenase	-	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N,ADH_zinc_N_2
k59_178085_1	1121405.dsmv_3574	1.73e-40	138.0	COG0256@1|root,COG0256@2|Bacteria,1RGY7@1224|Proteobacteria,42TIT@68525|delta/epsilon subdivisions,2WQ8U@28221|Deltaproteobacteria,2MKF7@213118|Desulfobacterales	28221|Deltaproteobacteria	J	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance	rplR	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904	-	ko:K02881	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L18p
k59_117486_1	526222.Desal_3655	3.15e-35	130.0	COG0381@1|root,COG0381@2|Bacteria,1QUYI@1224|Proteobacteria,42MSY@68525|delta/epsilon subdivisions,2WJXR@28221|Deltaproteobacteria,2M98J@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Belongs to the UDP-N-acetylglucosamine 2-epimerase family	wecB	-	5.1.3.14	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	M00362	R00420	RC00290	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase_2
k59_133355_1	335543.Sfum_2526	4.3e-54	179.0	COG1163@1|root,COG1163@2|Bacteria,1RFPD@1224|Proteobacteria,42ZF3@68525|delta/epsilon subdivisions,2WUZY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	TGS domain	-	-	-	ko:K06944	-	-	-	-	ko00000	-	-	-	MMR_HSR1,TGS
k59_223765_1	1265505.ATUG01000003_gene656	2.36e-15	75.1	COG0476@1|root,COG0476@2|Bacteria,1MW7H@1224|Proteobacteria,42Q7U@68525|delta/epsilon subdivisions,2WPC0@28221|Deltaproteobacteria,2MJIV@213118|Desulfobacterales	28221|Deltaproteobacteria	H	ThiF family	moeB	-	2.7.7.73	ko:K03148	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07459	RC00043	ko00000,ko00001,ko01000	-	-	-	ThiF
k59_178087_1	882.DVU_2958	1.16e-76	237.0	COG0730@1|root,COG0730@2|Bacteria,1NJ47@1224|Proteobacteria,42QRS@68525|delta/epsilon subdivisions,2WN5M@28221|Deltaproteobacteria,2MGEZ@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Sulfite exporter TauE/SafE	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
k59_178087_2	883.DvMF_1765	5.12e-46	153.0	2DDIC@1|root,32U1K@2|Bacteria,1NDK2@1224|Proteobacteria,42VX8@68525|delta/epsilon subdivisions,2WSEV@28221|Deltaproteobacteria,2MC5D@213115|Desulfovibrionales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_102887_1	909663.KI867150_gene248	1.67e-92	285.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,42N0C@68525|delta/epsilon subdivisions,2WJQQ@28221|Deltaproteobacteria,2MQT7@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	PFAM Aldehyde dehydrogenase	-	-	1.2.1.16,1.2.1.18,1.2.1.20,1.2.1.27,1.2.1.3,1.2.1.79,1.2.1.9	ko:K00128,ko:K00131,ko:K00135,ko:K00140	ko00010,ko00030,ko00053,ko00071,ko00250,ko00280,ko00310,ko00330,ko00340,ko00350,ko00380,ko00410,ko00561,ko00562,ko00620,ko00625,ko00640,ko00650,ko00760,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00053,map00071,map00250,map00280,map00310,map00330,map00340,map00350,map00380,map00410,map00561,map00562,map00620,map00625,map00640,map00650,map00760,map00903,map00981,map01100,map01110,map01120,map01130,map01200	M00013,M00027,M00135,M00308,M00633	R00264,R00631,R00705,R00706,R00710,R00713,R00714,R00904,R00922,R00935,R01058,R01752,R01986,R02401,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00004,RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500,RC02723,RC02817	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
k59_80202_1	1121438.JNJA01000005_gene1194	2.88e-11	60.8	COG1959@1|root,COG1959@2|Bacteria,1MZ1C@1224|Proteobacteria,42SPF@68525|delta/epsilon subdivisions,2WPVC@28221|Deltaproteobacteria,2MBCY@213115|Desulfovibrionales	28221|Deltaproteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
k59_80202_2	1121403.AUCV01000001_gene682	5.7e-12	67.0	COG4191@1|root,COG4191@2|Bacteria,1R891@1224|Proteobacteria,42P2C@68525|delta/epsilon subdivisions,2WJZT@28221|Deltaproteobacteria,2MIG9@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
k59_26538_1	744980.TRICHSKD4_3010	6.32e-36	131.0	COG4644@1|root,COG4644@2|Bacteria,1NYIE@1224|Proteobacteria,2UT3U@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4158
k59_80205_1	335543.Sfum_3479	1.45e-101	326.0	COG1197@1|root,COG1197@2|Bacteria,1MUXG@1224|Proteobacteria,42N8X@68525|delta/epsilon subdivisions,2WIVR@28221|Deltaproteobacteria,2MQ8P@213462|Syntrophobacterales	28221|Deltaproteobacteria	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
k59_80209_1	266762.HQ36_03200	1.24e-55	182.0	COG0005@1|root,COG0005@2|Bacteria,4NE4J@976|Bacteroidetes,2FM1B@200643|Bacteroidia,22X9V@171551|Porphyromonadaceae	976|Bacteroidetes	F	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate	xapA	-	2.4.2.1	ko:K03783	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244	RC00033,RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
k59_147693_1	933262.AXAM01000057_gene1536	3.46e-89	271.0	COG0473@1|root,COG0473@2|Bacteria,1MUH4@1224|Proteobacteria,42M8G@68525|delta/epsilon subdivisions,2WIYB@28221|Deltaproteobacteria,2MIG1@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate	leuB	-	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
k59_193294_1	314254.OA2633_05211	5.79e-35	134.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,2TQPZ@28211|Alphaproteobacteria,43WIS@69657|Hyphomonadaceae	28211|Alphaproteobacteria	M	Belongs to the peptidase S1C family	degP	GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ,PDZ_2,Trypsin_2
k59_147696_1	880072.Desac_2166	1.82e-64	214.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,1NBSJ@1224|Proteobacteria,42MXV@68525|delta/epsilon subdivisions,2WIIT@28221|Deltaproteobacteria,2MRG4@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain	porA	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR,POR_N,Transketolase_C
k59_26545_1	1121405.dsmv_0443	1.11e-98	300.0	COG1364@1|root,COG1364@2|Bacteria,1MU0T@1224|Proteobacteria,42M6S@68525|delta/epsilon subdivisions,2WJU8@28221|Deltaproteobacteria,2MIPX@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate	argJ	GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.3.1.1,2.3.1.35	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259,R02282	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	ArgJ
k59_196582_1	247490.KSU1_D0176	1.43e-37	138.0	COG1943@1|root,COG1943@2|Bacteria,2IYXS@203682|Planctomycetes	203682|Planctomycetes	L	Transposase IS200 like	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
k59_242257_1	879212.DespoDRAFT_02905	5.96e-66	212.0	COG4177@1|root,COG4177@2|Bacteria,1MV66@1224|Proteobacteria,42MAQ@68525|delta/epsilon subdivisions,2WKK0@28221|Deltaproteobacteria,2MINE@213118|Desulfobacterales	28221|Deltaproteobacteria	E	transport system permease	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
k59_52810_1	1121430.JMLG01000011_gene342	6.36e-157	457.0	COG0165@1|root,COG0165@2|Bacteria,1TNZ6@1239|Firmicutes,2489H@186801|Clostridia,260K5@186807|Peptococcaceae	186801|Clostridia	E	TIGRFAM argininosuccinate lyase	argH	-	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ASL_C2,Lyase_1
k59_6583_1	933262.AXAM01000082_gene779	1.57e-62	198.0	COG0716@1|root,COG0716@2|Bacteria,1MYWV@1224|Proteobacteria,42T4N@68525|delta/epsilon subdivisions,2WPT3@28221|Deltaproteobacteria,2MNUE@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Flavodoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	Flavodoxin_5
k59_151199_1	1121405.dsmv_0225	2.05e-48	166.0	COG0679@1|root,COG0679@2|Bacteria,1N1X9@1224|Proteobacteria,42R83@68525|delta/epsilon subdivisions,2WN00@28221|Deltaproteobacteria,2MJHD@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Membrane transport protein	-	-	-	ko:K07088	-	-	-	-	ko00000	-	-	-	Mem_trans
k59_98544_1	760568.Desku_1474	2.58e-62	204.0	COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,260VU@186807|Peptococcaceae	186801|Clostridia	G	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	-	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
k59_196597_1	1265505.ATUG01000001_gene2873	1.12e-28	116.0	COG0038@1|root,COG0517@1|root,COG0038@2|Bacteria,COG0517@2|Bacteria,1MV4K@1224|Proteobacteria,42PJQ@68525|delta/epsilon subdivisions,2WKR4@28221|Deltaproteobacteria,2MIMH@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Voltage gated chloride channel	-	-	-	ko:K03281	-	-	-	-	ko00000	2.A.49	-	-	CBS,Voltage_CLC
k59_242264_1	335543.Sfum_3302	4.4e-105	322.0	COG0173@1|root,COG0173@2|Bacteria,1MUXB@1224|Proteobacteria,42NC6@68525|delta/epsilon subdivisions,2WJEV@28221|Deltaproteobacteria,2MR5T@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
k59_22429_1	1265505.ATUG01000002_gene1877	1.04e-20	89.0	COG1913@1|root,COG1913@2|Bacteria,1NEU5@1224|Proteobacteria,42WCP@68525|delta/epsilon subdivisions,2X5BA@28221|Deltaproteobacteria,2MN8Z@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Peptidase family M54	-	-	-	ko:K06974	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M54
k59_151213_1	933262.AXAM01000027_gene2088	8.35e-39	133.0	COG1810@1|root,COG1810@2|Bacteria,1RG9Q@1224|Proteobacteria,42S52@68525|delta/epsilon subdivisions,2WNTC@28221|Deltaproteobacteria,2MK0C@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Domain of unknown function	-	-	-	-	-	-	-	-	-	-	-	-	DUF166
k59_219604_1	909663.KI867150_gene561	2.26e-90	268.0	COG1142@1|root,COG1142@2|Bacteria,1RBG7@1224|Proteobacteria,42R5G@68525|delta/epsilon subdivisions,2WMV5@28221|Deltaproteobacteria,2MR63@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	4fe-4S ferredoxin, iron-sulfur binding domain protein	bamC-1	-	-	ko:K19516	ko00362,ko01100,ko01120,map00362,map01100,map01120	M00541	R10961	RC01839	ko00000,ko00001,ko00002,ko01000	-	-	-	-
k59_242279_1	439235.Dalk_3288	1.28e-119	370.0	COG0046@1|root,COG0046@2|Bacteria,1MYN4@1224|Proteobacteria,42M08@68525|delta/epsilon subdivisions,2WITS@28221|Deltaproteobacteria,2MIFX@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C,PurS
k59_196616_1	400682.PAC_15704213	2.72e-32	119.0	KOG4012@1|root,KOG4012@2759|Eukaryota,38FHA@33154|Opisthokonta,3BS6T@33208|Metazoa	33208|Metazoa	B	nucleosome assembly	-	GO:0000228,GO:0000781,GO:0000784,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005694,GO:0005737,GO:0031974,GO:0031981,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044446,GO:0044454,GO:0044464,GO:0070013,GO:0098687	-	ko:K11275	-	-	-	-	ko00000,ko03036	-	-	-	Linker_histone
k59_29962_1	1230343.CANP01000035_gene2592	7.31e-17	85.1	COG2706@1|root,COG2706@2|Bacteria,1RB38@1224|Proteobacteria,1SNAF@1236|Gammaproteobacteria,1JE2M@118969|Legionellales	118969|Legionellales	G	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_45103_1	290400.Jann_1968	4.89e-05	48.1	COG1600@1|root,COG1600@2|Bacteria,1N0WQ@1224|Proteobacteria,2TV0D@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	dehalogenase'	-	-	-	-	-	-	-	-	-	-	-	-	Dehalogenase,Fer4_16
k59_45103_2	768706.Desor_2613	1.21e-14	72.4	COG1410@1|root,COG1410@2|Bacteria,1UV7K@1239|Firmicutes,25CEH@186801|Clostridia,260S6@186807|Peptococcaceae	186801|Clostridia	E	PFAM Pterin binding enzyme	-	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
k59_52832_1	335543.Sfum_1212	6.95e-56	192.0	COG0568@1|root,COG0568@2|Bacteria,1MVNJ@1224|Proteobacteria,42N2S@68525|delta/epsilon subdivisions,2WJ0E@28221|Deltaproteobacteria,2MQXV@213462|Syntrophobacterales	28221|Deltaproteobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	rpoD	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_ner,Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
k59_227289_1	880072.Desac_1856	2.1e-82	260.0	COG0476@1|root,COG0476@2|Bacteria	2|Bacteria	H	Involved in molybdopterin and thiamine biosynthesis, family 2	-	-	-	-	-	-	-	-	-	-	-	-	ThiF
k59_29965_1	439235.Dalk_3266	3.99e-71	240.0	COG0493@1|root,COG1148@1|root,COG0493@2|Bacteria,COG1148@2|Bacteria,1QUM4@1224|Proteobacteria,42MPP@68525|delta/epsilon subdivisions,2WJ3U@28221|Deltaproteobacteria,2MIA4@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_20,Pyr_redox_2
k59_196624_1	439235.Dalk_5173	5.34e-36	142.0	COG2204@1|root,COG4191@1|root,COG2204@2|Bacteria,COG4191@2|Bacteria,1R891@1224|Proteobacteria,42P2C@68525|delta/epsilon subdivisions,2WJZT@28221|Deltaproteobacteria,2MIG9@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
k59_242285_2	418443.A2I7Z4_9CAUD	3.32e-18	94.0	4QAIK@10239|Viruses,4QUPH@35237|dsDNA viruses  no RNA stage,4QPEB@28883|Caudovirales,4QP3P@10744|Podoviridae	10744|Podoviridae	S	phosphoprotein phosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_52836_1	1054213.HMPREF9946_01063	4.42e-08	57.8	COG0380@1|root,COG0380@2|Bacteria,1MUIY@1224|Proteobacteria,2TQMP@28211|Alphaproteobacteria,2JPVA@204441|Rhodospirillales	204441|Rhodospirillales	G	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor	otsA	-	2.4.1.15,2.4.1.347	ko:K00697	ko00500,ko01100,map00500,map01100	-	R02737	RC00005,RC00049,RC02748	ko00000,ko00001,ko01000,ko01003	-	GT20	-	Glyco_transf_20
k59_29970_1	161156.JQKW01000010_gene287	3.04e-82	249.0	COG0138@1|root,COG0138@2|Bacteria,2GHJA@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	F	MGS-like domain	-	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
k59_75752_1	656519.Halsa_1260	2.24e-33	132.0	COG0038@1|root,COG5002@1|root,COG0038@2|Bacteria,COG5002@2|Bacteria,1TPX0@1239|Firmicutes,247R4@186801|Clostridia	186801|Clostridia	P	Chloride transporter, ClC family	-	-	-	ko:K03281	-	-	-	-	ko00000	2.A.49	-	-	CBS,Voltage_CLC
k59_67882_1	289376.THEYE_A1412	4.44e-19	89.0	2CX8V@1|root,32T1H@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_196629_1	1499967.BAYZ01000065_gene6113	5.93e-26	101.0	COG3180@1|root,COG3180@2|Bacteria	2|Bacteria	S	Transition state regulatory protein AbrB	yhjN	-	-	ko:K07120	-	-	-	-	ko00000	-	-	-	AbrB
k59_242288_1	521045.Kole_2140	5.35e-42	149.0	COG0613@1|root,COG0613@2|Bacteria,2GCRI@200918|Thermotogae	200918|Thermotogae	S	PFAM PHP domain	-	-	3.1.3.97	ko:K07053	-	-	R00188,R11188	RC00078	ko00000,ko01000	-	-	-	PHP
k59_166347_1	305700.B447_16617	2.36e-63	209.0	COG1057@1|root,COG1057@2|Bacteria,1NNZ8@1224|Proteobacteria,2W09S@28216|Betaproteobacteria,2KXU4@206389|Rhodocyclales	206389|Rhodocyclales	H	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_166354_2	305700.B447_03303	1.01e-21	96.7	COG4249@1|root,COG4249@2|Bacteria	2|Bacteria	S	B-1 B cell differentiation	-	-	-	-	-	-	-	-	-	-	-	-	DUF4384,GUN4,GUN4_N,Peptidase_C13,Peptidase_C14
k59_67892_1	335543.Sfum_0664	2.73e-28	119.0	COG0309@1|root,COG0826@1|root,COG0309@2|Bacteria,COG0826@2|Bacteria,1MUQG@1224|Proteobacteria,42M8P@68525|delta/epsilon subdivisions,2X5K8@28221|Deltaproteobacteria,2MQGN@213462|Syntrophobacterales	28221|Deltaproteobacteria	O	PFAM peptidase U32	-	-	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_U32
k59_45125_1	629265.PMA4326_09740	2.32e-16	90.1	2DPZ4@1|root,32UN5@2|Bacteria,1RFK5@1224|Proteobacteria,1S5EH@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_181516_1	1125863.JAFN01000001_gene2835	2.57e-47	171.0	COG0493@1|root,COG0493@2|Bacteria,1MU2H@1224|Proteobacteria,42P5P@68525|delta/epsilon subdivisions,2WITN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_20,Fer4_9,Pyr_redox_2
k59_166369_1	96561.Dole_0376	5.16e-100	310.0	COG1274@1|root,COG1274@2|Bacteria,1MX3C@1224|Proteobacteria,42PRT@68525|delta/epsilon subdivisions,2WIWH@28221|Deltaproteobacteria,2MIPZ@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Phosphoenolpyruvate carboxykinase N-terminal domain	pckG	-	4.1.1.32	ko:K01596	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko03320,ko04068,ko04151,ko04152,ko04910,ko04920,ko04922,ko04931,ko04964,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map03320,map04068,map04151,map04152,map04910,map04920,map04922,map04931,map04964	M00003	R00431,R00726	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2638	PEPCK_C,PEPCK_N
k59_151273_1	1121405.dsmv_3261	1.69e-22	97.1	COG0484@1|root,COG0705@1|root,COG0484@2|Bacteria,COG0705@2|Bacteria,1MYFP@1224|Proteobacteria,42P0V@68525|delta/epsilon subdivisions,2WJGR@28221|Deltaproteobacteria,2MI6P@213118|Desulfobacterales	28221|Deltaproteobacteria	O	Rhomboid family	-	-	-	ko:K07059	-	-	-	-	ko00000	-	-	-	DnaJ_C,Rhomboid
k59_67910_1	1500259.JQLD01000002_gene3008	1.18e-09	64.3	COG2202@1|root,COG2982@1|root,COG3209@1|root,COG3210@1|root,COG5295@1|root,COG2202@2|Bacteria,COG2982@2|Bacteria,COG3209@2|Bacteria,COG3210@2|Bacteria,COG5295@2|Bacteria,1QUXB@1224|Proteobacteria,2TWTY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	U	PFAM SMP-30 Gluconolaconase	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin,DUF4347
k59_219650_1	1131269.AQVV01000004_gene584	1.45e-42	144.0	COG1898@1|root,COG1898@2|Bacteria	2|Bacteria	M	dTDP-4-dehydrorhamnose 3,5-epimerase activity	rfbC	-	5.1.3.13	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R06514	RC01531	ko00000,ko00001,ko00002,ko01000	-	-	-	dTDP_sugar_isom
k59_219650_2	1499686.BN1079_03204	5.23e-45	155.0	COG1091@1|root,COG1091@2|Bacteria,1MUXM@1224|Proteobacteria,1RSNR@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose	rfbD	-	1.1.1.133	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777	RC00182	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
k59_196678_1	1121405.dsmv_2307	2.63e-151	437.0	COG1032@1|root,COG1032@2|Bacteria,1MY2Y@1224|Proteobacteria,42NG3@68525|delta/epsilon subdivisions,2WJ95@28221|Deltaproteobacteria,2MJ57@213118|Desulfobacterales	28221|Deltaproteobacteria	C	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,DUF4070,Radical_SAM
k59_67923_1	1101195.Meth11DRAFT_0305	6.01e-18	87.8	COG0260@1|root,COG0260@2|Bacteria,1MUF9@1224|Proteobacteria,2VH79@28216|Betaproteobacteria,2KKR5@206350|Nitrosomonadales	206350|Nitrosomonadales	E	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides	pepA	-	3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17,Peptidase_M17_N
k59_30027_1	1304885.AUEY01000003_gene506	1.55e-73	238.0	COG3243@1|root,COG3243@2|Bacteria	2|Bacteria	I	poly(R)-hydroxyalkanoic acid synthase	-	-	-	ko:K03821	ko00650,map00650	-	R04254	RC00004	ko00000,ko00001,ko01000	-	-	-	-
k59_227355_1	1537715.JQFJ01000002_gene2379	3.72e-08	55.8	COG1664@1|root,COG1664@2|Bacteria,1MZN0@1224|Proteobacteria,2U5DW@28211|Alphaproteobacteria,2K66W@204457|Sphingomonadales	204457|Sphingomonadales	M	Integral membrane protein CcmA involved in cell shape determination	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
k59_75805_1	1313172.YM304_34320	9.43e-39	152.0	COG0457@1|root,COG2114@1|root,COG3899@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG3899@2|Bacteria,2GJRI@201174|Actinobacteria	201174|Actinobacteria	T	Adenylyl cyclase class-3 4 guanylyl cyclase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Guanylate_cyc,TPR_12
k59_6663_1	1121396.KB893046_gene3300	3.23e-31	134.0	COG2203@1|root,COG4191@1|root,COG2203@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MC4@68525|delta/epsilon subdivisions,2WIZU@28221|Deltaproteobacteria,2MIEE@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg,SBP_bac_3,sCache_2
k59_45154_2	1121918.ARWE01000001_gene562	9.76e-40	139.0	COG1176@1|root,COG1176@2|Bacteria,1MVFG@1224|Proteobacteria,43AFR@68525|delta/epsilon subdivisions,2WKHP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K11071	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	BPD_transp_1
k59_6667_1	933262.AXAM01000046_gene123	9.24e-91	283.0	COG0173@1|root,COG0173@2|Bacteria,1MUXB@1224|Proteobacteria,42NC6@68525|delta/epsilon subdivisions,2WJEV@28221|Deltaproteobacteria,2MI7X@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
k59_151304_2	999413.HMPREF1094_03884	1.02e-09	59.3	COG0655@1|root,COG0655@2|Bacteria,1TQKC@1239|Firmicutes,3VT0P@526524|Erysipelotrichia	526524|Erysipelotrichia	S	NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
k59_45161_1	264462.Bd0665	1.19e-65	213.0	COG3049@1|root,COG3049@2|Bacteria,1MWPQ@1224|Proteobacteria,42QQ7@68525|delta/epsilon subdivisions,2WTWM@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Linear amide C-N hydrolases, choloylglycine hydrolase family	-	-	3.5.1.24	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	-	R02797,R03975,R03977,R04486,R04487,R05835	RC00090,RC00096	ko00000,ko00001,ko01000	-	-	-	CBAH
k59_227365_1	118163.Ple7327_3825	1.23e-11	70.9	COG0428@1|root,COG0664@1|root,COG0428@2|Bacteria,COG0664@2|Bacteria,1G2YK@1117|Cyanobacteria,3VN15@52604|Pleurocapsales	1117|Cyanobacteria	PT	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Zip,cNMP_binding
k59_78978_1	1232437.KL661978_gene3837	7.75e-78	243.0	COG0042@1|root,COG0042@2|Bacteria,1MV5V@1224|Proteobacteria,42M3I@68525|delta/epsilon subdivisions,2WIXZ@28221|Deltaproteobacteria,2MI4J@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	-	-	-	-	-	-	-	-	-	-	-	-	Dus
k59_162233_1	335543.Sfum_1935	3.07e-88	275.0	COG1007@1|root,COG1007@2|Bacteria,1MV56@1224|Proteobacteria,42P7Z@68525|delta/epsilon subdivisions,2WKS0@28221|Deltaproteobacteria,2MQ9R@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
k59_18015_1	526222.Desal_3303	1.09e-77	242.0	COG0686@1|root,COG0686@2|Bacteria,1QTX1@1224|Proteobacteria,42MSF@68525|delta/epsilon subdivisions,2WKJ5@28221|Deltaproteobacteria,2M87G@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	Belongs to the AlaDH PNT family	ald	-	1.4.1.1	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	-	R00396	RC00008	ko00000,ko00001,ko01000	-	-	iAF987.Gmet_1099	AlaDh_PNT_C,AlaDh_PNT_N
k59_33295_1	1121405.dsmv_1296	5.52e-113	335.0	COG0674@1|root,COG0674@2|Bacteria,1NBSJ@1224|Proteobacteria,42MS1@68525|delta/epsilon subdivisions,2WJ97@28221|Deltaproteobacteria,2MI7P@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM Pyruvate flavodoxin ferredoxin oxidoreductase	korA	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR_N
k59_63703_1	1123371.ATXH01000010_gene691	1.18e-47	157.0	COG1959@1|root,COG1959@2|Bacteria,2GGXM@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
k59_18019_1	880072.Desac_2277	1.52e-30	116.0	COG0500@1|root,COG2226@2|Bacteria,1MX8I@1224|Proteobacteria,42P2Z@68525|delta/epsilon subdivisions,2WNJ6@28221|Deltaproteobacteria,2MRA3@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2)	ubiE	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
k59_40889_1	95619.PM1_0201095	2.06e-104	325.0	COG0188@1|root,COG0188@2|Bacteria,1MURI@1224|Proteobacteria,1RMTC@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule	parC	GO:0000819,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006265,GO:0006276,GO:0006725,GO:0006807,GO:0006996,GO:0007049,GO:0007059,GO:0007062,GO:0008150,GO:0008152,GO:0009330,GO:0009987,GO:0016020,GO:0016043,GO:0019897,GO:0019898,GO:0022402,GO:0030541,GO:0032991,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0098813,GO:1901360,GO:1901363	-	ko:K02621	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
k59_230545_1	756272.Plabr_3569	4.04e-19	85.5	COG0515@1|root,COG0515@2|Bacteria,2IZFV@203682|Planctomycetes	203682|Planctomycetes	KLT	serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_230545_2	439235.Dalk_1210	6.96e-56	195.0	COG2208@1|root,COG5000@1|root,COG2208@2|Bacteria,COG5000@2|Bacteria,1RCHY@1224|Proteobacteria,42R1G@68525|delta/epsilon subdivisions,2WMR7@28221|Deltaproteobacteria,2MJNU@213118|Desulfobacterales	28221|Deltaproteobacteria	T	protein phosphatase 2C domain protein	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	HAMP,SpoIIE
k59_177396_1	321846.PS417_16785	5.9e-41	148.0	COG4177@1|root,COG4177@2|Bacteria,1MV66@1224|Proteobacteria	1224|Proteobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
k59_207935_1	1172188.KB911822_gene707	1.13e-42	169.0	COG0642@1|root,COG2205@2|Bacteria,2I2M2@201174|Actinobacteria,4FFYD@85021|Intrasporangiaceae	201174|Actinobacteria	T	GAF domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF3365,GAF_2,HAMP,HATPase_c,HisKA,Response_reg
k59_207935_2	1395571.TMS3_0106935	1.03e-25	107.0	COG0834@1|root,COG0834@2|Bacteria,1RH2S@1224|Proteobacteria,1S84G@1236|Gammaproteobacteria	1236|Gammaproteobacteria	ET	Bacterial extracellular solute-binding proteins, family 3	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
k59_146925_1	485915.Dret_1795	1.13e-79	249.0	COG0475@1|root,COG0475@2|Bacteria,1RFKE@1224|Proteobacteria,43B2P@68525|delta/epsilon subdivisions,2X6GM@28221|Deltaproteobacteria,2M9P0@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	Sodium/hydrogen exchanger family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
k59_33306_1	1219080.VEZ01S_20_00860	1.6e-10	64.7	COG0628@1|root,COG0628@2|Bacteria,1MVX7@1224|Proteobacteria,1RNN1@1236|Gammaproteobacteria,1XSXA@135623|Vibrionales	135623|Vibrionales	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
k59_238127_1	1125863.JAFN01000001_gene2336	2.77e-58	192.0	COG3637@1|root,COG3637@2|Bacteria,1RG1M@1224|Proteobacteria,42VR0@68525|delta/epsilon subdivisions,2WS4Z@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_146928_1	1121405.dsmv_1977	3.38e-17	80.5	COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,42M88@68525|delta/epsilon subdivisions,2WIZI@28221|Deltaproteobacteria,2MJ2S@213118|Desulfobacterales	28221|Deltaproteobacteria	T	PFAM sigma-54 factor interaction domain-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,PAS_9,Sigma54_activat
k59_2795_2	237368.SCABRO_02885	2.34e-08	54.7	COG1064@1|root,COG1064@2|Bacteria,2IY4H@203682|Planctomycetes	203682|Planctomycetes	C	alcohol dehydrogenase	-	-	1.1.1.1	ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
k59_169740_1	1122180.Lokhon_01806	1.12e-09	58.2	COG0425@1|root,COG0425@2|Bacteria,1QAA2@1224|Proteobacteria,2VAUR@28211|Alphaproteobacteria,2P95M@245186|Loktanella	28211|Alphaproteobacteria	O	Sulfurtransferase TusA	-	-	-	-	-	-	-	-	-	-	-	-	TusA
k59_154860_1	96561.Dole_0536	1.94e-79	255.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,42M51@68525|delta/epsilon subdivisions,2WIVD@28221|Deltaproteobacteria,2MHZ9@213118|Desulfobacterales	28221|Deltaproteobacteria	NU	type II secretion system	pulE-3	-	-	ko:K02454	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSE,T2SSE_N
k59_116486_1	1329516.JPST01000005_gene1418	1.86e-92	280.0	COG4608@1|root,COG4608@2|Bacteria,1V36J@1239|Firmicutes,4H9YB@91061|Bacilli,27B9Q@186824|Thermoactinomycetaceae	91061|Bacilli	E	Oligopeptide/dipeptide transporter, C-terminal region	appF	-	-	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
k59_207951_1	338963.Pcar_0577	4.35e-62	204.0	COG3547@1|root,COG3547@2|Bacteria,1NCHY@1224|Proteobacteria,42TM4@68525|delta/epsilon subdivisions,2WR4U@28221|Deltaproteobacteria,43W2A@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_223069_1	555778.Hneap_0971	1.61e-127	388.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,1RMYC@1236|Gammaproteobacteria,1WX32@135613|Chromatiales	135613|Chromatiales	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.6	ko:K01535	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.3.3	-	-	Cation_ATPase_N,E1-E2_ATPase,Hydrolase
k59_215146_1	933262.AXAM01000011_gene1732	9.44e-30	116.0	COG1456@1|root,COG1456@2|Bacteria,1R8JC@1224|Proteobacteria,42Q7Q@68525|delta/epsilon subdivisions,2WJXT@28221|Deltaproteobacteria,2MIQZ@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Domain of unknown function (DUF3786)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3786,FeS
k59_25689_1	497964.CfE428DRAFT_2721	8.82e-31	120.0	COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,46U7Q@74201|Verrucomicrobia	74201|Verrucomicrobia	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source	-	-	6.3.5.1	ko:K01950	ko00760,ko01100,map00760,map01100	M00115	R00257	RC00010,RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase,NAD_synthase
k59_48389_2	335543.Sfum_2496	3.48e-71	223.0	COG2834@1|root,COG2834@2|Bacteria,1R5U8@1224|Proteobacteria,42MIS@68525|delta/epsilon subdivisions,2WMK7@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Outer membrane lipoprotein-sorting protein	-	-	-	-	-	-	-	-	-	-	-	-	LolA_like
k59_230579_1	1304885.AUEY01000059_gene2403	3.05e-44	157.0	COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,42MH9@68525|delta/epsilon subdivisions,2WJE0@28221|Deltaproteobacteria,2MIF7@213118|Desulfobacterales	28221|Deltaproteobacteria	U	General secretion pathway protein F	gspF	-	-	ko:K02455,ko:K02653	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSF
k59_139645_1	589865.DaAHT2_1931	5.52e-47	167.0	COG0773@1|root,COG0773@2|Bacteria,1MUC5@1224|Proteobacteria,42NMY@68525|delta/epsilon subdivisions,2WJ8S@28221|Deltaproteobacteria,2MHS5@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Belongs to the MurCDEF family	mpl	-	6.3.2.45	ko:K02558	-	-	-	-	ko00000,ko01000	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
k59_146938_1	330214.NIDE0751	2.1e-120	357.0	COG0017@1|root,COG0017@2|Bacteria	2|Bacteria	J	Asparaginyl-tRNA synthetase	asnS	GO:0003674,GO:0003824,GO:0004812,GO:0004816,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006421,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.22	ko:K01893	ko00970,map00970	M00359,M00360	R03648	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
k59_200158_1	913865.DOT_2081	1.19e-39	139.0	COG0193@1|root,COG0193@2|Bacteria,1V3NB@1239|Firmicutes,24HMC@186801|Clostridia,261YC@186807|Peptococcaceae	186801|Clostridia	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	-	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
k59_185386_2	1121403.AUCV01000022_gene3529	3.7e-39	140.0	COG0491@1|root,COG0491@2|Bacteria,1MX4H@1224|Proteobacteria,42PY0@68525|delta/epsilon subdivisions,2WJ2Y@28221|Deltaproteobacteria,2MKZK@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
k59_215162_1	1121406.JAEX01000007_gene2377	1.96e-36	138.0	COG0840@1|root,COG3681@1|root,COG0840@2|Bacteria,COG3681@2|Bacteria,1MW81@1224|Proteobacteria,42MIE@68525|delta/epsilon subdivisions,2WKPI@28221|Deltaproteobacteria,2M8G6@213115|Desulfovibrionales	28221|Deltaproteobacteria	NT	Belongs to the UPF0597 family	-	-	-	-	-	-	-	-	-	-	-	-	SDH_alpha
k59_131990_1	56780.SYN_01787	1.12e-57	201.0	COG0532@1|root,COG0532@2|Bacteria,1MV26@1224|Proteobacteria,42M5Q@68525|delta/epsilon subdivisions,2WIIX@28221|Deltaproteobacteria,2MQ8J@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,IF-2,IF2_N
k59_18050_1	1205680.CAKO01000002_gene3128	1.19e-69	222.0	COG3173@1|root,COG3173@2|Bacteria,1MWAK@1224|Proteobacteria,2TT2N@28211|Alphaproteobacteria,2JR4G@204441|Rhodospirillales	204441|Rhodospirillales	S	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
k59_18050_2	1223545.GS4_14_01430	1.77e-07	52.0	COG1960@1|root,COG1960@2|Bacteria,2GKQI@201174|Actinobacteria,4GAXB@85026|Gordoniaceae	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
k59_25693_1	1238190.AMQY01000021_gene1539	3.46e-28	109.0	COG2801@1|root,COG2801@2|Bacteria,1MVC8@1224|Proteobacteria,1RXYF@1236|Gammaproteobacteria,1XHWD@135619|Oceanospirillales	135619|Oceanospirillales	L	HTH-like domain	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve,rve_3
k59_25693_2	1569209.BBPH01000038_gene3285	1.13e-19	82.8	COG2963@1|root,COG2963@2|Bacteria,1N06K@1224|Proteobacteria,2U9BK@28211|Alphaproteobacteria,2PXQ7@265|Paracoccus	28211|Alphaproteobacteria	L	Transposase	-	-	-	ko:K07483	-	-	-	-	ko00000	-	-	-	HTH_Tnp_1
k59_48402_1	397948.Cmaq_0363	1.14e-15	76.3	COG0842@1|root,arCOG01467@2157|Archaea,2XQF4@28889|Crenarchaeota	28889|Crenarchaeota	V	PFAM ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
k59_48402_2	930945.SiRe_0322	9.71e-19	87.0	COG1131@1|root,arCOG00196@2157|Archaea,2XSQ2@28889|Crenarchaeota	28889|Crenarchaeota	V	Domain of unknown function (DUF4162)	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
k59_139665_1	290400.Jann_1975	8.69e-15	75.9	2CDFF@1|root,32RXP@2|Bacteria,1N26W@1224|Proteobacteria,2UDNJ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_208432_1	696747.NIES39_L03880	1.96e-10	65.9	COG0464@1|root,COG0464@2|Bacteria,1G04V@1117|Cyanobacteria,1H82W@1150|Oscillatoriales	1117|Cyanobacteria	O	PFAM ATPase family associated with various cellular activities (AAA)	-	-	-	-	-	-	-	-	-	-	-	-	AAA
k59_170200_1	335543.Sfum_2112	1.62e-91	278.0	COG0821@1|root,COG0821@2|Bacteria,1MUAX@1224|Proteobacteria,42M3V@68525|delta/epsilon subdivisions,2WJJ4@28221|Deltaproteobacteria,2MQ70@213462|Syntrophobacterales	28221|Deltaproteobacteria	I	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate	ispG	GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576	1.17.7.1,1.17.7.3	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R08689,R10859	RC01486	ko00000,ko00001,ko00002,ko01000	-	-	-	GcpE
k59_208434_1	1304885.AUEY01000073_gene1461	9.15e-20	91.3	COG1652@1|root,COG2885@1|root,COG1652@2|Bacteria,COG2885@2|Bacteria,1MZTV@1224|Proteobacteria,42R5H@68525|delta/epsilon subdivisions,2WNZS@28221|Deltaproteobacteria,2MJUT@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Belongs to the ompA family	pal	-	-	ko:K03640	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	OmpA
k59_208434_2	96561.Dole_2210	2.39e-08	60.8	COG0823@1|root,COG0823@2|Bacteria,1MV09@1224|Proteobacteria,42PHP@68525|delta/epsilon subdivisions,2WIXN@28221|Deltaproteobacteria,2MHR4@213118|Desulfobacterales	28221|Deltaproteobacteria	U	Involved in the TonB-independent uptake of proteins	tolB	GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0019534,GO:0022857,GO:0051179,GO:0051234,GO:0055085,GO:1901998	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40,TolB_N
k59_109477_1	326427.Cagg_0669	4.59e-18	89.0	COG5184@1|root,COG5184@2|Bacteria,2G8WU@200795|Chloroflexi,3765G@32061|Chloroflexia	32061|Chloroflexia	DZ	PFAM regulator of chromosome condensation, RCC1	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_238395_1	694427.Palpr_1681	8.49e-80	246.0	COG0119@1|root,COG0119@2|Bacteria,4NHR2@976|Bacteroidetes,2FRGF@200643|Bacteroidia,22YPQ@171551|Porphyromonadaceae	976|Bacteroidetes	E	HMGL-like	-	-	4.1.3.39	ko:K01666	ko00360,ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00360,map00362,map00621,map00622,map01100,map01120,map01220	M00545,M00569	R00750	RC00307,RC00371	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	DmpG_comm,HMGL-like
k59_125091_2	765911.Thivi_2283	3.66e-44	160.0	COG0542@1|root,COG0542@2|Bacteria,1MVBH@1224|Proteobacteria,1RMZH@1236|Gammaproteobacteria,1WX5Q@135613|Chromatiales	135613|Chromatiales	O	associated with various cellular activities	-	-	-	ko:K11907	ko02025,ko03070,map02025,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	AAA,AAA_2,ClpB_D2-small
k59_170207_1	933262.AXAM01000015_gene85	4.39e-91	276.0	COG2255@1|root,COG2255@2|Bacteria,1MU38@1224|Proteobacteria,42M99@68525|delta/epsilon subdivisions,2WJ2Q@28221|Deltaproteobacteria,2MHYU@213118|Desulfobacterales	28221|Deltaproteobacteria	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	-	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
k59_3081_1	1115512.EH105704_16_00040	1.41e-11	70.9	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	NT	chemotaxis, protein	bdlA	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal,PAS_3,PAS_4,PAS_9
k59_3081_2	484019.THA_1190	4.37e-09	62.0	COG0643@1|root,COG2198@1|root,COG0643@2|Bacteria,COG2198@2|Bacteria,2GCE3@200918|Thermotogae	200918|Thermotogae	NT	Signal transducing histidine kinase, homodimeric	-	GO:0003674,GO:0005488,GO:0005515,GO:0019904	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt,P2
k59_94431_1	1232437.KL661972_gene4767	6.38e-16	83.2	COG0715@1|root,COG2909@1|root,COG0715@2|Bacteria,COG2909@2|Bacteria,1MVZZ@1224|Proteobacteria,42QAQ@68525|delta/epsilon subdivisions,2WJQN@28221|Deltaproteobacteria,2MJ4A@213118|Desulfobacterales	1224|Proteobacteria	K	Positively regulates the transcription of the maltose regulon whose gene products are responsible for uptake and catabolism of malto-oligosaccharides. Binds and recognizes a DNA motif (called the malT box) 5'-GGA TG GA-3'	malT	-	-	ko:K03556	-	-	-	-	ko00000,ko03000	-	-	-	AAA_16,GerE,TPR_19,TPR_4,TPR_8
k59_200607_1	1449126.JQKL01000055_gene2204	1.47e-49	167.0	COG1145@1|root,COG1145@2|Bacteria,1TPAZ@1239|Firmicutes,249NJ@186801|Clostridia,26832@186813|unclassified Clostridiales	186801|Clostridia	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_6
k59_33824_1	880072.Desac_2850	6.02e-24	97.4	COG1024@1|root,COG1024@2|Bacteria,1N2V7@1224|Proteobacteria,42UXR@68525|delta/epsilon subdivisions,2WQCT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	PFAM Enoyl-CoA hydratase isomerase	-	-	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
k59_33824_2	63737.Npun_R1256	1.67e-55	183.0	COG1171@1|root,COG1171@2|Bacteria,1G22X@1117|Cyanobacteria,1HKIV@1161|Nostocales	1117|Cyanobacteria	E	PFAM Pyridoxal-phosphate dependent enzyme	-	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
k59_116882_1	1125863.JAFN01000001_gene1816	2.56e-31	130.0	COG2982@1|root,COG2982@2|Bacteria,1NVUY@1224|Proteobacteria,42P4T@68525|delta/epsilon subdivisions,2WJR1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	AsmA-like C-terminal region	-	-	-	ko:K07289	-	-	-	-	ko00000	-	-	-	AsmA,AsmA_2,DUF748
k59_71659_2	1121324.CLIT_2c00070	3.47e-69	223.0	COG0477@1|root,COG2814@2|Bacteria,1V0Z5@1239|Firmicutes,24B0J@186801|Clostridia	186801|Clostridia	EGP	PFAM Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
k59_170218_1	596152.DesU5LDRAFT_1230	7.35e-16	83.2	COG1034@1|root,COG1034@2|Bacteria,1P8MN@1224|Proteobacteria,42PT5@68525|delta/epsilon subdivisions,2WIPN@28221|Deltaproteobacteria,2M94M@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	NADH-quinone oxidoreductase, chain G	nuoG-2	-	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
k59_147262_1	335543.Sfum_1742	5.63e-30	112.0	COG0071@1|root,COG0071@2|Bacteria,1N7C7@1224|Proteobacteria,42U0T@68525|delta/epsilon subdivisions,2WQ88@28221|Deltaproteobacteria,2MS3K@213462|Syntrophobacterales	28221|Deltaproteobacteria	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
k59_185846_1	631362.Thi970DRAFT_00233	1.82e-36	139.0	COG3464@1|root,COG3464@2|Bacteria,1N5CJ@1224|Proteobacteria,1T4WB@1236|Gammaproteobacteria,1WZSX@135613|Chromatiales	1236|Gammaproteobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_41285_1	1123392.AQWL01000019_gene25	1.95e-05	53.1	COG2319@1|root,COG2319@2|Bacteria,1MWJA@1224|Proteobacteria,2VI8Q@28216|Betaproteobacteria	28216|Betaproteobacteria	V	WD40 repeats	-	-	-	-	-	-	-	-	-	-	-	-	WD40
k59_76923_1	909663.KI867150_gene213	5.89e-62	212.0	COG0457@1|root,COG0457@2|Bacteria,1NNJ6@1224|Proteobacteria,42PBD@68525|delta/epsilon subdivisions,2WKWJ@28221|Deltaproteobacteria,2MRCI@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	PFAM Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2,TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8
k59_152632_1	1307761.L21SP2_0921	5.64e-42	157.0	COG5000@1|root,COG5000@2|Bacteria,2J5RG@203691|Spirochaetes	203691|Spirochaetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_4,PAS_8
k59_152632_2	1280954.HPO_14621	3.54e-11	65.9	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2TQPG@28211|Alphaproteobacteria,43X2P@69657|Hyphomonadaceae	28211|Alphaproteobacteria	T	COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains	tacA	GO:0003674,GO:0003700,GO:0004857,GO:0006355,GO:0008073,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0010967,GO:0019219,GO:0019222,GO:0030234,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0033238,GO:0042979,GO:0043086,GO:0044092,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050790,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0065009,GO:0080090,GO:0098772,GO:0140110,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activ_2,Sigma54_activat
k59_228297_1	933262.AXAM01000017_gene3141	9.28e-172	487.0	COG1150@1|root,COG1150@2|Bacteria,1QWNB@1224|Proteobacteria,43BTA@68525|delta/epsilon subdivisions,2X741@28221|Deltaproteobacteria,2MI1V@213118|Desulfobacterales	28221|Deltaproteobacteria	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_22
k59_129819_2	338963.Pcar_0432	5.23e-84	254.0	COG3647@1|root,COG3647@2|Bacteria,1N7NB@1224|Proteobacteria,42SI3@68525|delta/epsilon subdivisions,2WPVX@28221|Deltaproteobacteria,43UYD@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Predicted membrane protein (DUF2238)	-	-	-	ko:K08984	-	-	-	-	ko00000	-	-	-	DUF2238
k59_122232_1	1459636.NTE_02550	8.31e-70	235.0	COG1009@1|root,arCOG01539@2157|Archaea,41SC4@651137|Thaumarchaeota	651137|Thaumarchaeota	C	TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain L	-	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M,Proton_antipo_N
k59_114605_1	1265505.ATUG01000002_gene1391	5.58e-24	107.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42N0F@68525|delta/epsilon subdivisions,2WJAE@28221|Deltaproteobacteria,2MIUP@213118|Desulfobacterales	28221|Deltaproteobacteria	NT	PFAM chemotaxis sensory transducer	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CZB,HAMP,MCPsignal
k59_144954_1	909663.KI867150_gene1352	2.19e-12	68.2	COG1073@1|root,COG1073@2|Bacteria,1QUD5@1224|Proteobacteria,42Q84@68525|delta/epsilon subdivisions,2WP99@28221|Deltaproteobacteria,2MQR3@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Serine aminopeptidase, S33	-	-	-	ko:K06889,ko:K07397	-	-	-	-	ko00000	-	-	-	Hydrolase_4
k59_198053_1	512565.AMIS_18930	6.33e-21	98.6	COG4191@1|root,COG4191@2|Bacteria,2IF7B@201174|Actinobacteria,4DH3U@85008|Micromonosporales	201174|Actinobacteria	T	PAS fold	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,PAS_4,Response_reg
k59_175348_1	1033802.SSPSH_000070	4.2e-13	66.2	2CJPW@1|root,32SAH@2|Bacteria,1NAJ3@1224|Proteobacteria,1SAPE@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_144955_1	1227454.C446_15211	3.09e-12	65.1	COG0071@1|root,arCOG01833@2157|Archaea,2XY1D@28890|Euryarchaeota,23WAJ@183963|Halobacteria	183963|Halobacteria	O	Belongs to the small heat shock protein (HSP20) family	hsp20b	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
k59_8516_1	1121405.dsmv_2749	5.02e-74	245.0	COG0058@1|root,COG0058@2|Bacteria,1MW4J@1224|Proteobacteria,42MEQ@68525|delta/epsilon subdivisions,2WIPF@28221|Deltaproteobacteria,2MIPG@213118|Desulfobacterales	28221|Deltaproteobacteria	G	phosphorylase	glgP	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	DUF3417,Phosphorylase
k59_16043_1	1265505.ATUG01000003_gene320	3.33e-69	233.0	COG0204@1|root,COG1647@1|root,COG0204@2|Bacteria,COG1647@2|Bacteria,1MVZP@1224|Proteobacteria,42NBK@68525|delta/epsilon subdivisions,2WIUP@28221|Deltaproteobacteria,2MHMP@213118|Desulfobacterales	28221|Deltaproteobacteria	I	Phosphate acyltransferases	-	-	3.1.1.1	ko:K03928	-	-	-	-	ko00000,ko01000	-	-	-	Acyltransferase,Hydrolase_4
k59_107074_1	269799.Gmet_1622	1.56e-75	229.0	COG2131@1|root,COG2131@2|Bacteria,1RD1P@1224|Proteobacteria,42RHI@68525|delta/epsilon subdivisions,2WNGV@28221|Deltaproteobacteria,43U1G@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	PFAM CMP dCMP deaminase zinc-binding	comEB	-	3.5.4.12	ko:K01493	ko00240,ko01100,map00240,map01100	M00429	R01663	RC00074	ko00000,ko00001,ko00002,ko01000,ko02044	-	-	-	dCMP_cyt_deam_1
k59_107074_2	1121918.ARWE01000001_gene1295	1.45e-15	72.4	COG1327@1|root,COG1327@2|Bacteria,1RE7V@1224|Proteobacteria,42SJP@68525|delta/epsilon subdivisions,2WPK0@28221|Deltaproteobacteria,43SIP@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	ATP cone domain	nrdR	-	-	ko:K07738	-	-	-	-	ko00000,ko03000	-	-	-	ATP-cone
k59_167649_1	1265505.ATUG01000001_gene4653	1.5e-72	245.0	COG2202@1|root,COG4191@1|root,COG2202@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42PKS@68525|delta/epsilon subdivisions,2WJBK@28221|Deltaproteobacteria,2MHTB@213118|Desulfobacterales	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_9,Response_reg
k59_23732_1	644282.Deba_0601	1.56e-46	161.0	COG0613@1|root,COG0613@2|Bacteria,1QV9S@1224|Proteobacteria,43BP1@68525|delta/epsilon subdivisions,2X70C@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	SMART phosphoesterase PHP domain protein	-	-	3.1.3.97	ko:K07053	-	-	R00188,R11188	RC00078	ko00000,ko01000	-	-	-	PHP
k59_182888_1	439235.Dalk_3480	7.56e-42	147.0	COG0505@1|root,COG0505@2|Bacteria,1MUB9@1224|Proteobacteria,42KZG@68525|delta/epsilon subdivisions,2WIQ5@28221|Deltaproteobacteria,2MIKI@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Belongs to the CarA family	carA	-	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_sm_chain,GATase
k59_175359_1	1408428.JNJP01000004_gene2947	1.75e-29	117.0	COG0492@1|root,COG0492@2|Bacteria,1MV15@1224|Proteobacteria,42MHR@68525|delta/epsilon subdivisions,2WIY8@28221|Deltaproteobacteria,2M9DZ@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
k59_23734_1	207559.Dde_1994	3.8e-19	90.1	COG2203@1|root,COG2203@2|Bacteria,1NI96@1224|Proteobacteria,42WWD@68525|delta/epsilon subdivisions,2WT0R@28221|Deltaproteobacteria,2M91Z@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	GAF domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2
k59_38916_1	525897.Dbac_0564	2.01e-31	126.0	COG0823@1|root,COG0823@2|Bacteria,1MX4U@1224|Proteobacteria,42PEP@68525|delta/epsilon subdivisions,2WJUC@28221|Deltaproteobacteria,2M91V@213115|Desulfovibrionales	28221|Deltaproteobacteria	U	Involved in the tonB-independent uptake of proteins	tmcD	-	-	-	-	-	-	-	-	-	-	-	PD40
k59_107075_1	1121405.dsmv_1096	3.28e-73	247.0	COG1132@1|root,COG1132@2|Bacteria,1MWTY@1224|Proteobacteria,42N23@68525|delta/epsilon subdivisions,2WKW2@28221|Deltaproteobacteria,2MMXV@213118|Desulfobacterales	28221|Deltaproteobacteria	V	ABC transporter transmembrane region	-	-	-	ko:K02021	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.110,3.A.1.112,3.A.1.113,3.A.1.117,3.A.1.21	-	-	ABC_membrane,ABC_tran
k59_107075_2	485915.Dret_1795	5.96e-32	123.0	COG0475@1|root,COG0475@2|Bacteria,1RFKE@1224|Proteobacteria,43B2P@68525|delta/epsilon subdivisions,2X6GM@28221|Deltaproteobacteria,2M9P0@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	Sodium/hydrogen exchanger family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
k59_69167_2	335543.Sfum_1905	8.89e-78	243.0	COG2896@1|root,COG2896@2|Bacteria,1MW3W@1224|Proteobacteria,42NBV@68525|delta/epsilon subdivisions,2WK0F@28221|Deltaproteobacteria,2MQTX@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate	moaA	GO:0003674,GO:0003824,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0071704,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.99.22	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394	RC03420	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Fer4_14,Mob_synth_C,Radical_SAM
k59_23735_1	485918.Cpin_2419	7.46e-50	171.0	COG0073@1|root,COG0073@2|Bacteria,4P176@976|Bacteroidetes,1IWP0@117747|Sphingobacteriia	976|Bacteroidetes	J	RNA ligase	-	-	-	-	-	-	-	-	-	-	-	-	RNA_ligase
k59_84285_1	933262.AXAM01000008_gene1980	2.59e-59	207.0	COG0760@1|root,COG0760@2|Bacteria,1MWV0@1224|Proteobacteria,42MPK@68525|delta/epsilon subdivisions,2WJM1@28221|Deltaproteobacteria,2MHM6@213118|Desulfobacterales	28221|Deltaproteobacteria	O	PFAM PpiC-type peptidyl-prolyl cis-trans isomerase	nifM	-	5.2.1.8	ko:K03770	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N_3
k59_38918_1	1121405.dsmv_1642	1.61e-54	186.0	COG1488@1|root,COG1488@2|Bacteria,1R5W0@1224|Proteobacteria,42NQQ@68525|delta/epsilon subdivisions,2WJ4V@28221|Deltaproteobacteria,2MMNR@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP	-	-	6.3.4.21	ko:K00763	ko00760,ko01100,map00760,map01100	-	R01724	RC00033	ko00000,ko00001,ko01000	-	-	-	NAPRTase,QRPTase_C
k59_138032_1	90813.JQMT01000001_gene359	9.49e-76	239.0	COG3328@1|root,COG3328@2|Bacteria,1MU4P@1224|Proteobacteria,1RNB3@1236|Gammaproteobacteria,462ZZ@72273|Thiotrichales	72273|Thiotrichales	L	Transposase, Mutator family	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_mut
k59_213757_1	522772.Dacet_1307	9.68e-14	72.8	COG1934@1|root,COG1934@2|Bacteria,2GFYT@200930|Deferribacteres	200930|Deferribacteres	S	OstA-like protein	-	-	-	ko:K09774	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	OstA
k59_77422_1	234267.Acid_5892	8.4e-46	166.0	COG1032@1|root,COG1032@2|Bacteria	2|Bacteria	C	radical SAM domain protein	-	-	-	ko:K22318	-	-	-	-	ko00000	-	-	-	B12-binding,Radical_SAM
k59_77423_1	96561.Dole_2540	2.11e-06	48.1	COG2209@1|root,COG2209@2|Bacteria,1R33S@1224|Proteobacteria,42N3Q@68525|delta/epsilon subdivisions,2WJSA@28221|Deltaproteobacteria,2MIWQ@213118|Desulfobacterales	28221|Deltaproteobacteria	C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol	nqrE	-	1.6.5.8	ko:K00350	-	-	-	-	ko00000,ko01000	-	-	-	Rnf-Nqr
k59_77423_2	96561.Dole_2539	3.06e-61	194.0	COG1347@1|root,COG1347@2|Bacteria,1MUZR@1224|Proteobacteria,42QT5@68525|delta/epsilon subdivisions,2WN1N@28221|Deltaproteobacteria,2MHSZ@213118|Desulfobacterales	28221|Deltaproteobacteria	C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol	nqrD	-	1.6.5.8	ko:K00349	-	-	-	-	ko00000,ko01000	-	-	-	Rnf-Nqr
k59_1416_1	96561.Dole_1719	2.4e-76	256.0	COG1196@1|root,COG1196@2|Bacteria,1MUAQ@1224|Proteobacteria,42MN9@68525|delta/epsilon subdivisions,2WJZF@28221|Deltaproteobacteria,2MHU0@213118|Desulfobacterales	28221|Deltaproteobacteria	D	Required for chromosome condensation and partitioning	smc	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
k59_1416_2	443144.GM21_3297	9.03e-83	261.0	COG0552@1|root,COG0552@2|Bacteria,1MUDU@1224|Proteobacteria,42N3Z@68525|delta/epsilon subdivisions,2WIPM@28221|Deltaproteobacteria,43TJM@69541|Desulfuromonadales	28221|Deltaproteobacteria	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components	ftsY	-	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
k59_47003_2	335543.Sfum_2852	1.82e-57	190.0	COG1496@1|root,COG1496@2|Bacteria,1MW2H@1224|Proteobacteria,42SE9@68525|delta/epsilon subdivisions,2WMQE@28221|Deltaproteobacteria,2MRRD@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Multi-copper polyphenol oxidoreductase laccase	-	-	-	ko:K05810	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase_4
k59_77424_1	335543.Sfum_0406	3.64e-66	214.0	COG0607@1|root,COG1633@1|root,COG0607@2|Bacteria,COG1633@2|Bacteria,1MZPW@1224|Proteobacteria,42NX5@68525|delta/epsilon subdivisions,2WMJ4@28221|Deltaproteobacteria,2MRIH@213462|Syntrophobacterales	28221|Deltaproteobacteria	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese,Rubrerythrin
k59_183381_1	96561.Dole_1461	3.6e-100	309.0	COG0369@1|root,COG1151@2|Bacteria,1NYH2@1224|Proteobacteria,42NE1@68525|delta/epsilon subdivisions,2WIVX@28221|Deltaproteobacteria,2MINQ@213118|Desulfobacterales	28221|Deltaproteobacteria	C	TIGRFAM carbon-monoxide dehydrogenase, catalytic subunit	-	-	1.2.7.4	ko:K00198	ko00633,ko00680,ko00720,ko01120,ko01200,map00633,map00680,map00720,map01120,map01200	M00377	R07157,R08034	RC00250,RC02800	ko00000,ko00001,ko00002,ko01000	-	-	-	Prismane
k59_213760_2	1122915.AUGY01000014_gene2794	2.96e-23	99.4	COG0318@1|root,COG0318@2|Bacteria,1TPSX@1239|Firmicutes,4HA2G@91061|Bacilli,26R1I@186822|Paenibacillaceae	91061|Bacilli	IQ	PFAM AMP-dependent synthetase and ligase	lcfA	-	6.2.1.3	ko:K01897,ko:K18661	ko00061,ko00071,ko00280,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map00280,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280,R03383	RC00004,RC00014,RC00137	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
k59_206257_1	525897.Dbac_2662	3.54e-41	142.0	COG0745@1|root,COG0745@2|Bacteria,1MY2Z@1224|Proteobacteria,42MP1@68525|delta/epsilon subdivisions,2WJPD@28221|Deltaproteobacteria,2M7S0@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	PFAM response regulator receiver	phoB	-	-	ko:K07657	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
k59_206257_2	335543.Sfum_2891	4.35e-07	52.8	COG5002@1|root,COG5002@2|Bacteria,1MWF3@1224|Proteobacteria,42NB5@68525|delta/epsilon subdivisions,2WJGX@28221|Deltaproteobacteria,2MQCA@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	Signal transduction histidine kinase	-	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_8,PAS_9,sCache_like
k59_92412_1	335543.Sfum_1829	2.2e-111	352.0	COG1924@1|root,COG3580@1|root,COG1924@2|Bacteria,COG3580@2|Bacteria,1PKG6@1224|Proteobacteria,42MY4@68525|delta/epsilon subdivisions,2WJFI@28221|Deltaproteobacteria,2MQ8R@213462|Syntrophobacterales	28221|Deltaproteobacteria	I	BadF BadG BcrA BcrD	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG,DUF2229
k59_1424_1	43989.cce_4219	8.18e-62	203.0	COG0126@1|root,COG0126@2|Bacteria,1G2FM@1117|Cyanobacteria,3KFNN@43988|Cyanothece	1117|Cyanobacteria	F	Belongs to the phosphoglycerate kinase family	pgk	-	2.7.2.3	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01512	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
k59_168139_1	880072.Desac_0501	1.19e-211	612.0	COG2202@1|root,COG2204@1|root,COG3290@1|root,COG2202@2|Bacteria,COG2204@2|Bacteria,COG3290@2|Bacteria,1MU0N@1224|Proteobacteria,43BK2@68525|delta/epsilon subdivisions,2X6XX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Sigma-54 factor interaction domain-containing protein	-	-	-	ko:K02481,ko:K07712,ko:K07713	ko02020,map02020	M00497,M00499	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,PAS_4,Response_reg,Sigma54_activat
k59_213766_1	879212.DespoDRAFT_00963	1e-46	166.0	COG2821@1|root,COG2821@2|Bacteria,1MXD4@1224|Proteobacteria,42P7C@68525|delta/epsilon subdivisions,2WKKF@28221|Deltaproteobacteria,2MIJE@213118|Desulfobacterales	28221|Deltaproteobacteria	M	PFAM MltA	-	-	-	ko:K08304	-	-	-	-	ko00000,ko01000,ko01011	-	GH102	-	3D,MltA
k59_236579_1	309799.DICTH_1915	4.23e-25	105.0	COG0312@1|root,COG0312@2|Bacteria	2|Bacteria	S	metallopeptidase activity	tldE2	-	-	-	-	-	-	-	-	-	-	-	PmbA_TldD
k59_153250_1	335543.Sfum_2466	2.73e-64	215.0	COG1042@1|root,COG1042@2|Bacteria,1MW98@1224|Proteobacteria,42KZW@68525|delta/epsilon subdivisions,2WIQB@28221|Deltaproteobacteria,2MR9S@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	CoA binding domain	-	-	6.2.1.13	ko:K01905,ko:K22224	ko00010,ko00620,ko00640,ko01100,ko01120,map00010,map00620,map00640,map01100,map01120	-	R00229,R00920	RC00004,RC00012,RC00014	ko00000,ko00001,ko01000,ko01004	-	-	-	ATP-grasp_5,CoA_binding_2,Succ_CoA_lig
k59_206267_1	290402.Cbei_3304	1.89e-08	60.1	2EK3J@1|root,33DTZ@2|Bacteria,1VPD9@1239|Firmicutes,24QPR@186801|Clostridia,36MVY@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_62287_1	187272.Mlg_0671	1.49e-78	254.0	COG0591@1|root,COG0591@2|Bacteria	2|Bacteria	E	symporter activity	-	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
k59_228958_1	96561.Dole_2313	9.39e-27	114.0	COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,42MEA@68525|delta/epsilon subdivisions,2WIW6@28221|Deltaproteobacteria,2MI74@213118|Desulfobacterales	28221|Deltaproteobacteria	KT	Sigma-54 interaction domain	-	-	2.1.1.80	ko:K00575	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	HTH_8,PAS_4,PAS_9,Sigma54_activat
k59_160814_1	1121405.dsmv_1994	3.01e-53	169.0	COG0838@1|root,COG0838@2|Bacteria,1RGUT@1224|Proteobacteria,42U92@68525|delta/epsilon subdivisions,2WQCK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoA	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0050136,GO:0055114,GO:0098796,GO:1902494	1.6.5.3	ko:K00330	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q4
k59_160814_2	335543.Sfum_1942	5.46e-51	178.0	COG0377@1|root,COG0649@1|root,COG0852@1|root,COG0377@2|Bacteria,COG0649@2|Bacteria,COG0852@2|Bacteria,1MVIN@1224|Proteobacteria,42M9G@68525|delta/epsilon subdivisions,2WIS7@28221|Deltaproteobacteria,2MR1T@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoBCD	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072521,GO:1901135,GO:1901360,GO:1901564	1.6.5.3	ko:K00333,ko:K13378,ko:K13380	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa,Complex1_49kDa,Oxidored_q6
k59_183397_1	1307759.JOMJ01000004_gene2844	4.45e-67	226.0	COG1132@1|root,COG1132@2|Bacteria,1MWTY@1224|Proteobacteria,42N23@68525|delta/epsilon subdivisions,2WKW2@28221|Deltaproteobacteria,2M7Z1@213115|Desulfovibrionales	28221|Deltaproteobacteria	V	ABC transporter, transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	ABC_membrane,ABC_tran
k59_47024_1	1121405.dsmv_0917	2.61e-87	267.0	COG0697@1|root,COG0697@2|Bacteria,1PIF3@1224|Proteobacteria,42SMV@68525|delta/epsilon subdivisions,2WPAJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
k59_236588_1	941449.dsx2_0821	1.13e-76	259.0	COG4775@1|root,COG4775@2|Bacteria,1MU0D@1224|Proteobacteria,42MMA@68525|delta/epsilon subdivisions,2WIZB@28221|Deltaproteobacteria,2M8BJ@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamA	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
k59_92429_1	994573.T472_0205885	2.55e-43	153.0	COG0303@1|root,COG0303@2|Bacteria,1TRHU@1239|Firmicutes,248IF@186801|Clostridia	186801|Clostridia	H	Probable molybdopterin binding domain	-	-	-	-	-	-	-	-	-	-	-	-	MoCF_biosynth
k59_236590_1	998674.ATTE01000001_gene3080	2.05e-33	126.0	COG1262@1|root,COG1262@2|Bacteria,1NQ5K@1224|Proteobacteria,1S2PN@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	PFAM Sulphatase-modifying factor	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
k59_47026_1	1121441.AUCX01000022_gene782	4.13e-39	139.0	COG0406@1|root,COG0406@2|Bacteria,1NPC4@1224|Proteobacteria,42SM1@68525|delta/epsilon subdivisions,2WP4T@28221|Deltaproteobacteria,2MBYM@213115|Desulfovibrionales	28221|Deltaproteobacteria	G	PFAM Phosphoglycerate mutase	-	-	5.4.2.12	ko:K15634	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	His_Phos_1
k59_183403_1	1121403.AUCV01000022_gene3525	1.02e-41	152.0	COG3103@1|root,COG3103@2|Bacteria,1MVX1@1224|Proteobacteria,42PXB@68525|delta/epsilon subdivisions,2WJKN@28221|Deltaproteobacteria,2MJ1J@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Sh3 type 3 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF1302
k59_221497_1	335543.Sfum_4014	4.34e-165	472.0	COG0409@1|root,COG0409@2|Bacteria,1MU1F@1224|Proteobacteria,42M6R@68525|delta/epsilon subdivisions,2WJDQ@28221|Deltaproteobacteria,2MR11@213462|Syntrophobacterales	28221|Deltaproteobacteria	O	TIGRFAM hydrogenase expression formation protein HypD	hypD	-	-	ko:K04654	-	-	-	-	ko00000	-	-	iAF987.Gmet_0117	HypD
k59_47028_1	7029.ACYPI38380-PA	1.03e-30	128.0	2D0FB@1|root,2SE02@2759|Eukaryota,38VJ7@33154|Opisthokonta,3CNAZ@33208|Metazoa,3DRPU@33213|Bilateria,4228A@6656|Arthropoda,3SQBY@50557|Insecta	33208|Metazoa	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,Transposase_1
k59_138054_1	1140003.I573_01108	2.5e-29	112.0	COG0193@1|root,COG0193@2|Bacteria,1V3NB@1239|Firmicutes,4HH2Z@91061|Bacilli,4AZY0@81852|Enterococcaceae	91061|Bacilli	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
k59_138054_2	1121405.dsmv_3388	2.73e-15	75.1	COG3808@1|root,COG3808@2|Bacteria,1MUQ3@1224|Proteobacteria,42N1H@68525|delta/epsilon subdivisions,2WJ0R@28221|Deltaproteobacteria,2MHVX@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase
k59_206294_1	335543.Sfum_1046	2.29e-21	92.0	COG2046@1|root,COG2046@2|Bacteria,1MUQB@1224|Proteobacteria,42NAI@68525|delta/epsilon subdivisions,2WJYY@28221|Deltaproteobacteria,2MR3M@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	Belongs to the sulfate adenylyltransferase family	sat	-	2.7.1.25,2.7.7.4	ko:K00958,ko:K13811	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00509,R00529,R04928,R04929	RC00002,RC00078,RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase,ATP-sulfurylase,PUA_2
k59_198618_1	880072.Desac_0014	1.34e-78	252.0	COG1219@1|root,COG1219@2|Bacteria,1MWIZ@1224|Proteobacteria,42N1Z@68525|delta/epsilon subdivisions,2WJUS@28221|Deltaproteobacteria,2MR6M@213462|Syntrophobacterales	28221|Deltaproteobacteria	O	Belongs to the ClpX chaperone family	-	-	-	-	-	-	-	-	-	-	-	-	AAA_2,ClpB_D2-small
k59_160842_1	517418.Ctha_0688	5.9e-29	120.0	COG0784@1|root,COG2202@1|root,COG2203@1|root,COG3829@1|root,COG4191@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG2203@2|Bacteria,COG3829@2|Bacteria,COG4191@2|Bacteria,1FEIU@1090|Chlorobi	1090|Chlorobi	T	ATP-binding region, ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_9,Response_reg
k59_153274_1	765952.PUV_27640	1.16e-95	286.0	COG0214@1|root,COG0214@2|Bacteria,2JG0Q@204428|Chlamydiae	204428|Chlamydiae	H	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively	pdxS	-	4.3.3.6	ko:K06215	ko00750,map00750	-	R07456	RC00010,RC01783,RC03043	ko00000,ko00001,ko01000	-	-	-	SOR_SNZ
k59_175901_1	1121918.ARWE01000001_gene3520	2.87e-06	48.5	COG1192@1|root,COG1192@2|Bacteria,1MV43@1224|Proteobacteria,42MTF@68525|delta/epsilon subdivisions,2WJ6X@28221|Deltaproteobacteria,43T9A@69541|Desulfuromonadales	28221|Deltaproteobacteria	D	PFAM Cobyrinic acid a,c-diamide synthase	soj	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
k59_175901_2	97139.C824_05071	1.44e-65	214.0	COG1475@1|root,COG1475@2|Bacteria,1TQ2B@1239|Firmicutes,249VV@186801|Clostridia,36DTS@31979|Clostridiaceae	186801|Clostridia	K	Belongs to the ParB family	spo0J	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
k59_47043_1	246969.TAM4_1931	2.24e-66	218.0	COG0112@1|root,arCOG00070@2157|Archaea,2XU0H@28890|Euryarchaeota,242QX@183968|Thermococci	183968|Thermococci	E	Catalyzes the reversible interconversion of serine and glycine with a modified folate serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
k59_107589_2	243265.plu3406	8.37e-12	66.6	COG1783@1|root,COG1783@2|Bacteria,1R66A@1224|Proteobacteria,1RQFD@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Phage terminase, large subunit	-	-	-	ko:K06909	-	-	-	-	ko00000	-	-	-	Terminase_3,Terminase_3C
k59_107589_3	266265.Bxe_B1505	0.000419	45.1	COG1396@1|root,COG1396@2|Bacteria,1NE6R@1224|Proteobacteria,2VWUN@28216|Betaproteobacteria,1KG4E@119060|Burkholderiaceae	28216|Betaproteobacteria	K	Helix-turn-helix domain	hipB	-	-	ko:K15773	-	-	-	-	ko00000,ko02048,ko03000	-	-	-	HTH_19,HTH_3,HTH_31
k59_107589_6	1622193.A0A0E3XAM5_9CAUD	4.48e-22	92.8	4QB4F@10239|Viruses,4QR9M@28883|Caudovirales,4QM3Z@10699|Siphoviridae	10699|Siphoviridae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_61778_2	1121413.JMKT01000008_gene1470	6.58e-27	104.0	COG0355@1|root,COG0355@2|Bacteria,1RHE4@1224|Proteobacteria,42TII@68525|delta/epsilon subdivisions,2WPVK@28221|Deltaproteobacteria,2MBW9@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpC	GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_DE,ATP-synt_DE_N
k59_182912_1	1232437.KL661961_gene3040	5.89e-27	100.0	2EDHV@1|root,337DV@2|Bacteria,1NEJZ@1224|Proteobacteria,42V5G@68525|delta/epsilon subdivisions,2WRIF@28221|Deltaproteobacteria,2MKYD@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_182912_2	335543.Sfum_0378	8.92e-105	314.0	COG0683@1|root,COG0683@2|Bacteria,1MX94@1224|Proteobacteria,42PYP@68525|delta/epsilon subdivisions,2WMA1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	PFAM Extracellular ligand-binding receptor	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
k59_182915_1	269799.Gmet_0002	5.42e-51	176.0	COG0592@1|root,COG0592@2|Bacteria,1MVD9@1224|Proteobacteria,42NQW@68525|delta/epsilon subdivisions,2WJZM@28221|Deltaproteobacteria,43T1D@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	dnaN	-	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
k59_23769_1	1380391.JIAS01000001_gene2744	1.52e-32	125.0	COG1073@1|root,COG1073@2|Bacteria,1RIWI@1224|Proteobacteria,2UAKC@28211|Alphaproteobacteria,2JSGU@204441|Rhodospirillales	204441|Rhodospirillales	S	Serine aminopeptidase, S33	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Hydrolase_4
k59_61782_1	933262.AXAM01000042_gene1831	1.81e-70	228.0	COG2759@1|root,COG2759@2|Bacteria,1MUR8@1224|Proteobacteria,42MKE@68525|delta/epsilon subdivisions,2WJF1@28221|Deltaproteobacteria,2MJ0Z@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Belongs to the formate--tetrahydrofolate ligase family	fhs	-	6.3.4.3	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R00943	RC00026,RC00111	ko00000,ko00001,ko00002,ko01000	-	-	-	FTHFS
k59_107114_1	1394176.AWUO01000016_gene626	9.02e-11	69.7	COG5184@1|root,COG5184@2|Bacteria,2ID2P@201174|Actinobacteria,4D2SI@85004|Bifidobacteriales	201174|Actinobacteria	DZ	Listeria-Bacteroides repeat domain (List_Bact_rpt)	-	-	-	-	-	-	-	-	-	-	-	-	Flg_new,RCC1
k59_69189_1	565033.GACE_1691	9.43e-44	156.0	COG1960@1|root,arCOG01707@2157|Archaea,2XT5S@28890|Euryarchaeota,245Z3@183980|Archaeoglobi	183980|Archaeoglobi	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
k59_137467_1	1232410.KI421412_gene200	3.56e-36	140.0	COG1652@1|root,COG1652@2|Bacteria,1MUBV@1224|Proteobacteria,42QS9@68525|delta/epsilon subdivisions,2WN3H@28221|Deltaproteobacteria,43SES@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Lysin motif	-	-	-	-	-	-	-	-	-	-	-	-	LysM
k59_31300_1	484770.UFO1_1271	1.91e-58	193.0	COG1073@1|root,COG1073@2|Bacteria,1TPW7@1239|Firmicutes	1239|Firmicutes	S	Hydrolases of the alpha beta superfamily	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Hydrolase_4,Peptidase_S15
k59_182924_1	1125863.JAFN01000001_gene3206	6.51e-64	210.0	COG2159@1|root,COG2159@2|Bacteria,1QZ3W@1224|Proteobacteria,42PKB@68525|delta/epsilon subdivisions,2WM59@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	PFAM transposase, IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_4
k59_61787_1	96561.Dole_3044	2.87e-103	316.0	COG0465@1|root,COG0465@2|Bacteria,1MU6J@1224|Proteobacteria,42M4Z@68525|delta/epsilon subdivisions,2WJ0D@28221|Deltaproteobacteria,2MIPH@213118|Desulfobacterales	28221|Deltaproteobacteria	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
k59_129874_2	1123279.ATUS01000002_gene90	1.15e-28	107.0	COG3070@1|root,COG3070@2|Bacteria,1N8X8@1224|Proteobacteria,1SC6J@1236|Gammaproteobacteria,1J6W2@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	K	TfoX N-terminal domain	-	-	-	ko:K07343	-	-	-	-	ko00000	-	-	-	TfoX_N
k59_129874_3	457398.HMPREF0326_01224	1.38e-41	142.0	2C9KR@1|root,32RPF@2|Bacteria,1MZXP@1224|Proteobacteria,42UJQ@68525|delta/epsilon subdivisions,2WQ5C@28221|Deltaproteobacteria,2MBEN@213115|Desulfovibrionales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_152684_1	485916.Dtox_3784	3.05e-58	187.0	COG2201@1|root,COG2201@2|Bacteria,1VUR7@1239|Firmicutes,2505U@186801|Clostridia,2650Y@186807|Peptococcaceae	186801|Clostridia	NT	CheB methylesterase	-	-	3.1.1.61,3.5.1.44	ko:K03412	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest
k59_167682_1	246199.CUS_7758	2.11e-10	65.1	COG3735@1|root,COG3735@2|Bacteria,1V7NU@1239|Firmicutes,24IJ8@186801|Clostridia,3WJ4J@541000|Ruminococcaceae	186801|Clostridia	S	TraB family	-	-	-	ko:K09973	-	-	-	-	ko00000	-	-	-	TraB
k59_198081_2	1121085.AUCI01000002_gene4021	2.36e-15	70.1	29SGJ@1|root,30DMJ@2|Bacteria,1UBFB@1239|Firmicutes,4IMU0@91061|Bacilli,1ZKUH@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_160298_1	224325.AF_0248	2.22e-14	77.4	COG1902@1|root,arCOG00615@2157|Archaea,2XT27@28890|Euryarchaeota	28890|Euryarchaeota	C	COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_FMN
k59_99522_1	396588.Tgr7_1733	2e-44	162.0	COG1538@1|root,COG1538@2|Bacteria,1R705@1224|Proteobacteria,1S0X1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	MU	PFAM Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
k59_198086_1	667014.Thein_0419	2.21e-80	253.0	COG1921@1|root,COG1921@2|Bacteria,2GHB4@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	E	Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis	selA	-	2.9.1.1	ko:K01042	ko00450,ko00970,map00450,map00970	-	R08219	RC01246	ko00000,ko00001,ko01000	-	-	-	SelA
k59_114644_1	1125863.JAFN01000001_gene1148	1.3e-42	149.0	COG1893@1|root,COG1893@2|Bacteria,1PGV8@1224|Proteobacteria,42T8E@68525|delta/epsilon subdivisions,2WPSV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Ketopantoate reductase PanE/ApbA C terminal	-	-	1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000	-	-	-	ApbA,ApbA_C
k59_114644_2	502025.Hoch_2192	2.32e-27	106.0	COG0824@1|root,COG0824@2|Bacteria,1Q2J2@1224|Proteobacteria,433TX@68525|delta/epsilon subdivisions,2X3FR@28221|Deltaproteobacteria,2YVWT@29|Myxococcales	28221|Deltaproteobacteria	S	Thioesterase-like superfamily	-	-	3.1.2.23	ko:K01075	ko00130,ko00362,ko01100,ko01110,ko01120,map00130,map00362,map01100,map01110,map01120	-	R01301	RC00004,RC00174	ko00000,ko00001,ko01000	-	-	-	4HBT
k59_122306_1	933262.AXAM01000048_gene2591	4.79e-88	285.0	COG0046@1|root,COG0046@2|Bacteria,1MYN4@1224|Proteobacteria,42M08@68525|delta/epsilon subdivisions,2WITS@28221|Deltaproteobacteria,2MIFX@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C,PurS
k59_236083_1	643562.Daes_0033	5.79e-26	116.0	COG2984@1|root,COG5002@1|root,COG2984@2|Bacteria,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,42NK9@68525|delta/epsilon subdivisions,2WMCQ@28221|Deltaproteobacteria,2MH9G@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	ABC_sub_bind,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
k59_46467_1	1379281.AVAG01000033_gene484	2.44e-34	119.0	COG1837@1|root,COG1837@2|Bacteria,1N7IX@1224|Proteobacteria,42TXI@68525|delta/epsilon subdivisions,2WQBS@28221|Deltaproteobacteria,2MCGN@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Belongs to the UPF0109 family	-	-	-	ko:K06960	-	-	-	-	ko00000	-	-	-	KH_4
k59_76985_1	1307759.JOMJ01000004_gene2863	8.24e-84	256.0	COG0115@1|root,COG0115@2|Bacteria,1MVB0@1224|Proteobacteria,42MKX@68525|delta/epsilon subdivisions,2WKXU@28221|Deltaproteobacteria,2M80I@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
k59_69213_1	643562.Daes_0732	4.06e-23	102.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,42M0W@68525|delta/epsilon subdivisions,2WIK8@28221|Deltaproteobacteria,2M8CQ@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	Diguanylate cyclase phosphodiesterase with PAS PAC sensor(S)	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,HAMP,PAS,PAS_4,PAS_9,sCache_3_2
k59_122310_1	177437.HRM2_01830	6.33e-43	151.0	COG1080@1|root,COG1080@2|Bacteria,1MUT8@1224|Proteobacteria,42P77@68525|delta/epsilon subdivisions,2WK7E@28221|Deltaproteobacteria,2MIQB@213118|Desulfobacterales	28221|Deltaproteobacteria	G	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)	-	-	2.7.3.9	ko:K08483	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	8.A.7	-	-	PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C
k59_46469_1	706587.Desti_5497	1.98e-132	388.0	COG0407@1|root,COG0407@2|Bacteria,1R9IN@1224|Proteobacteria,42Q1Q@68525|delta/epsilon subdivisions,2WMDE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	PFAM Uroporphyrinogen decarboxylase (URO-D)	-	-	-	-	-	-	-	-	-	-	-	-	URO-D
k59_114656_1	269482.Bcep1808_1170	9.63e-111	335.0	COG5323@1|root,COG5323@2|Bacteria,1MW8S@1224|Proteobacteria	1224|Proteobacteria	S	ATP-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Terminase_3,Terminase_6,Terminase_6C
k59_76989_1	335543.Sfum_0927	2.37e-53	174.0	COG1974@1|root,COG1974@2|Bacteria,1MW80@1224|Proteobacteria,42PAH@68525|delta/epsilon subdivisions,2WKSM@28221|Deltaproteobacteria,2MS4X@213462|Syntrophobacterales	28221|Deltaproteobacteria	K	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair	lexA	-	3.4.21.88	ko:K01356,ko:K03503	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	LexA_DNA_bind,Peptidase_S24
k59_122317_1	1265505.ATUG01000003_gene181	3.84e-54	184.0	COG0044@1|root,COG0044@2|Bacteria,1MVXY@1224|Proteobacteria,42MJ9@68525|delta/epsilon subdivisions,2WJH8@28221|Deltaproteobacteria,2MI0K@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily	pyrC	GO:0003674,GO:0003824,GO:0004038,GO:0004151,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046390,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
k59_220992_1	237368.SCABRO_03173	1.53e-39	154.0	COG0493@1|root,COG0493@2|Bacteria,2J2W6@203682|Planctomycetes	203682|Planctomycetes	E	2Fe-2S iron-sulfur cluster binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer2_4,Fer4_20,Pyr_redox_2
k59_84319_1	1185876.BN8_02675	2.75e-35	138.0	COG0784@1|root,COG3604@1|root,COG0784@2|Bacteria,COG3604@2|Bacteria,4PMAT@976|Bacteroidetes,47Y62@768503|Cytophagia	976|Bacteroidetes	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	-	ko:K02584	ko02020,map02020	-	-	-	ko00000,ko00001,ko03000	-	-	-	GAF,GAF_2,GAF_3,HTH_8,PAS_9,Response_reg,Sigma54_activat
k59_145040_1	1121405.dsmv_2317	1.03e-09	57.8	COG2518@1|root,COG2518@2|Bacteria,1MXQC@1224|Proteobacteria,42QXM@68525|delta/epsilon subdivisions,2WMZI@28221|Deltaproteobacteria,2MNC9@213118|Desulfobacterales	28221|Deltaproteobacteria	O	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	pcm	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
k59_145040_2	1121405.dsmv_2318	4.31e-56	194.0	COG0421@1|root,COG0421@2|Bacteria,1P220@1224|Proteobacteria,42NG6@68525|delta/epsilon subdivisions,2WIRU@28221|Deltaproteobacteria,2MK6C@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	-	-	-	-	-	-	-	-	-	-	-	-	Spermine_synth
k59_38969_1	335543.Sfum_1925	8.37e-31	126.0	COG0699@1|root,COG0699@2|Bacteria,1R3WJ@1224|Proteobacteria,42N0G@68525|delta/epsilon subdivisions,2WKFJ@28221|Deltaproteobacteria,2MRED@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Dynamin family	-	-	-	-	-	-	-	-	-	-	-	-	Dynamin_N
k59_228368_1	795359.TOPB45_1626	2.3e-135	394.0	COG0172@1|root,COG0172@2|Bacteria,2GGY4@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	J	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
k59_228368_2	944564.HMPREF9200_0591	1.39e-06	48.1	COG0776@1|root,COG0776@2|Bacteria,1V9XQ@1239|Firmicutes,4H539@909932|Negativicutes	909932|Negativicutes	L	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions	hup	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
k59_54067_1	1121396.KB893077_gene745	1.66e-89	279.0	COG1075@1|root,COG1075@2|Bacteria,1R5PF@1224|Proteobacteria,43BHB@68525|delta/epsilon subdivisions,2X6VQ@28221|Deltaproteobacteria,2MMMX@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Alpha/beta hydrolase of unknown function (DUF915)	-	-	-	-	-	-	-	-	-	-	-	-	DUF915
k59_23829_1	641491.DND132_1750	6.78e-23	100.0	COG2304@1|root,COG2885@1|root,COG2304@2|Bacteria,COG2885@2|Bacteria,1R7WJ@1224|Proteobacteria,42QJK@68525|delta/epsilon subdivisions,2WJX0@28221|Deltaproteobacteria,2M7W6@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Belongs to the ompA family	-	-	-	ko:K03286	-	-	-	-	ko00000,ko02000	1.B.6	-	-	OmpA,TSP_3,VWA,VWA_2
k59_190468_1	1279009.ADICEAN_03353	1.67e-31	129.0	COG4547@1|root,COG4932@1|root,COG5644@1|root,COG4547@2|Bacteria,COG4932@2|Bacteria,COG5644@2|Bacteria,4PKCH@976|Bacteroidetes	976|Bacteroidetes	M	chlorophyll binding	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,DUF11,SdrD_B
k59_137490_1	243090.RB12799	2.58e-40	152.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,2IXQR@203682|Planctomycetes	203682|Planctomycetes	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
k59_129935_1	935948.KE386495_gene1221	3.1e-67	211.0	COG5012@1|root,COG5012@2|Bacteria,1V1P0@1239|Firmicutes,24G08@186801|Clostridia,42FJI@68295|Thermoanaerobacterales	186801|Clostridia	S	Methionine synthase B12-binding module cap domain protein	-	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2
k59_77000_1	1304885.AUEY01000057_gene674	6.39e-48	165.0	COG0232@1|root,COG0232@2|Bacteria,1R6QQ@1224|Proteobacteria,42M0H@68525|delta/epsilon subdivisions,2WJ33@28221|Deltaproteobacteria,2MHN1@213118|Desulfobacterales	28221|Deltaproteobacteria	F	SMART metal-dependent phosphohydrolase HD region	-	-	3.1.5.1	ko:K01129	ko00230,map00230	-	R01856	RC00017	ko00000,ko00001,ko01000	-	-	-	HD,HD_assoc
k59_228377_1	1265505.ATUG01000001_gene4479	3.39e-92	273.0	COG0454@1|root,COG0456@2|Bacteria,1RDVM@1224|Proteobacteria,42X40@68525|delta/epsilon subdivisions,2WSVA@28221|Deltaproteobacteria,2MMZF@213118|Desulfobacterales	28221|Deltaproteobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
k59_31348_1	1285586.H131_21907	1.5e-37	145.0	COG5525@1|root,COG5525@2|Bacteria,1TQBY@1239|Firmicutes,4HD7Q@91061|Bacilli,3IZ5D@400634|Lysinibacillus	91061|Bacilli	S	Phage terminase large subunit (GpA)	-	-	-	-	-	-	-	-	-	-	-	-	Terminase_GpA
k59_190479_1	439235.Dalk_4262	2.94e-23	103.0	COG0664@1|root,COG1033@1|root,COG2199@1|root,COG0664@2|Bacteria,COG1033@2|Bacteria,COG3706@2|Bacteria,1MUE1@1224|Proteobacteria,42ME2@68525|delta/epsilon subdivisions,2WJRI@28221|Deltaproteobacteria,2MJQ7@213118|Desulfobacterales	28221|Deltaproteobacteria	K	MMPL family	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	GGDEF,LolA_like,MMPL,cNMP_binding
k59_137492_1	266265.Bxe_C0838	1.39e-105	323.0	COG3547@1|root,COG3547@2|Bacteria,1MW0N@1224|Proteobacteria,2VWYN@28216|Betaproteobacteria,1K8UX@119060|Burkholderiaceae	28216|Betaproteobacteria	L	Transposase IS116/IS110/IS902 family	-	-	-	ko:K07486	-	-	-	-	ko00000	-	-	-	Transposase_20
k59_77012_1	335543.Sfum_2118	1.05e-188	540.0	COG0539@1|root,COG1093@1|root,COG0539@2|Bacteria,COG1093@2|Bacteria,1MVAV@1224|Proteobacteria,42M29@68525|delta/epsilon subdivisions,2WJ0X@28221|Deltaproteobacteria,2MR1P@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence	rpsA	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
k59_167717_1	1121405.dsmv_2231	1.02e-19	83.2	2DNPA@1|root,32YE5@2|Bacteria,1NFYV@1224|Proteobacteria,43C5B@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	Stress responsive A/B Barrel Domain	-	-	-	-	-	-	-	-	-	-	-	-	Dabb
k59_167717_2	1121405.dsmv_3212	1.26e-29	108.0	2EFC1@1|root,3394Y@2|Bacteria,1NB39@1224|Proteobacteria,42WHM@68525|delta/epsilon subdivisions,2WSCI@28221|Deltaproteobacteria,2MM1K@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_8596_1	404380.Gbem_3149	2.03e-49	177.0	COG0204@1|root,COG1647@1|root,COG0204@2|Bacteria,COG1647@2|Bacteria,1MVZP@1224|Proteobacteria,42NBK@68525|delta/epsilon subdivisions,2WIUP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	Serine aminopeptidase, S33	-	-	3.1.1.1	ko:K03928	-	-	-	-	ko00000,ko01000	-	-	-	Acyltransferase,Hydrolase_4
k59_175992_1	96561.Dole_2381	4.86e-76	247.0	COG1283@1|root,COG1283@2|Bacteria,1MUDE@1224|Proteobacteria,42PW9@68525|delta/epsilon subdivisions,2WJTI@28221|Deltaproteobacteria,2MJ12@213118|Desulfobacterales	28221|Deltaproteobacteria	P	PFAM Na Pi-cotransporter	-	-	-	ko:K03324	-	-	-	-	ko00000,ko02000	2.A.58.2	-	-	Na_Pi_cotrans,PhoU
k59_107638_2	439235.Dalk_4147	6.33e-40	139.0	COG0207@1|root,COG0207@2|Bacteria,1Q4ZG@1224|Proteobacteria,42QWZ@68525|delta/epsilon subdivisions,2WMY5@28221|Deltaproteobacteria,2MJKN@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Thymidylate synthase	-	-	2.1.1.45	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	M00053	R02101	RC00219,RC00332	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylat_synt
k59_213841_1	1121405.dsmv_3468	1e-65	208.0	COG1280@1|root,COG1280@2|Bacteria,1RF18@1224|Proteobacteria,42RK6@68525|delta/epsilon subdivisions,2WNHB@28221|Deltaproteobacteria,2MKAF@213118|Desulfobacterales	28221|Deltaproteobacteria	E	LysE type translocator	-	-	-	-	-	-	-	-	-	-	-	-	LysE
k59_229079_1	335283.Neut_2010	0.000733	46.6	COG0845@1|root,COG0845@2|Bacteria,1MU8D@1224|Proteobacteria,2VH9K@28216|Betaproteobacteria,371TP@32003|Nitrosomonadales	28216|Betaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	HlyD_D23
k59_229079_2	493475.GARC_2785	6.69e-38	134.0	COG1136@1|root,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,1RNUJ@1236|Gammaproteobacteria,4673X@72275|Alteromonadaceae	1236|Gammaproteobacteria	V	ATPases associated with a variety of cellular activities	macB	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
k59_183468_3	246197.MXAN_2170	3.57e-49	197.0	COG1372@1|root,COG4733@1|root,COG1372@2|Bacteria,COG4733@2|Bacteria,1P9S5@1224|Proteobacteria	1224|Proteobacteria	L	Fibronectin type 3 domain	-	-	-	-	-	-	-	-	-	-	-	-	fn3
k59_100173_2	177437.HRM2_11240	0.000942	41.2	COG1014@1|root,COG1014@2|Bacteria,1RBZA@1224|Proteobacteria,42QT3@68525|delta/epsilon subdivisions,2X6H9@28221|Deltaproteobacteria,2MJ4W@213118|Desulfobacterales	28221|Deltaproteobacteria	C	indolepyruvate ferredoxin oxidoreductase, beta subunit	-	-	1.2.7.8	ko:K00180	-	-	-	-	br01601,ko00000,ko01000	-	-	-	POR
k59_122952_1	309799.DICTH_1693	2.1e-31	118.0	COG1913@1|root,COG1913@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	ko:K06974	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M54
k59_229081_1	1121918.ARWE01000001_gene3580	1.2e-11	64.3	COG1148@1|root,COG1148@2|Bacteria,1QUM4@1224|Proteobacteria,42MPP@68525|delta/epsilon subdivisions,2WJ3U@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	4Fe-4S ferredoxin iron-sulfur binding domain protein	bamE	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_7,Pyr_redox_2
k59_229081_2	1125863.JAFN01000001_gene1551	7.57e-05	42.4	COG1908@1|root,COG1908@2|Bacteria,1RCZY@1224|Proteobacteria,42T3M@68525|delta/epsilon subdivisions,2WPVI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Methyl-viologen-reducing hydrogenase, delta subunit	-	-	-	-	-	-	-	-	-	-	-	-	FlpD
k59_16667_1	634956.Geoth_0798	1.23e-50	198.0	COG5283@1|root,COG5412@1|root,COG5283@2|Bacteria,COG5412@2|Bacteria,1TQ28@1239|Firmicutes,4ITVP@91061|Bacilli,1WE4X@129337|Geobacillus	91061|Bacilli	S	Phage tail tape measure protein, TP901 family	-	-	-	-	-	-	-	-	-	-	-	-	PhageMin_Tail
k59_100177_1	1121396.KB893060_gene2872	7.34e-78	242.0	COG0604@1|root,COG0604@2|Bacteria,1MWBD@1224|Proteobacteria,42PQH@68525|delta/epsilon subdivisions,2WM5W@28221|Deltaproteobacteria,2MN4X@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Zinc-binding dehydrogenase	-	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N,ADH_zinc_N_2
k59_97670_1	177437.HRM2_03790	3.99e-86	268.0	COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,42MEA@68525|delta/epsilon subdivisions,2WIW6@28221|Deltaproteobacteria,2MI74@213118|Desulfobacterales	28221|Deltaproteobacteria	KT	Sigma-54 interaction domain	-	-	2.1.1.80	ko:K00575	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	HTH_8,PAS_4,PAS_9,Sigma54_activat
k59_189234_1	1232437.KL662020_gene828	1.18e-16	79.3	COG3608@1|root,COG3608@2|Bacteria,1Q5G3@1224|Proteobacteria,42MSH@68525|delta/epsilon subdivisions,2WKM8@28221|Deltaproteobacteria,2MKPY@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Carboxypeptidase controlling helical cell shape catalytic	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M99,Peptidase_M99_C
k59_189234_2	1232437.KL662020_gene829	3.8e-78	240.0	COG1876@1|root,COG1876@2|Bacteria,1RB64@1224|Proteobacteria,42R4D@68525|delta/epsilon subdivisions,2WMS5@28221|Deltaproteobacteria,2MJNK@213118|Desulfobacterales	28221|Deltaproteobacteria	M	D-alanyl-D-alanine carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	VanY
k59_195713_1	96561.Dole_2019	1.06e-65	209.0	COG1122@1|root,COG1122@2|Bacteria,1QN6E@1224|Proteobacteria,42QNR@68525|delta/epsilon subdivisions,2WMRD@28221|Deltaproteobacteria,2MIN4@213118|Desulfobacterales	28221|Deltaproteobacteria	P	PFAM ABC transporter	-	-	-	ko:K02006	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	ABC_tran
k59_67039_2	335543.Sfum_0168	4.8e-50	163.0	COG1145@1|root,COG1145@2|Bacteria,1QWP6@1224|Proteobacteria,43BU8@68525|delta/epsilon subdivisions,2X759@28221|Deltaproteobacteria,2MRTJ@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	NIL	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_4,Fer4_7,NIL
k59_189241_1	1493510.A0A0E3F5A9_9CAUD	1.53e-30	117.0	4QB5I@10239|Viruses,4QPQ9@28883|Caudovirales,4QI9F@10662|Myoviridae	10662|Myoviridae	S	Type III restriction enzyme, res subunit	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_189241_2	444861.E3SPL3_9CAUD	5.26e-73	222.0	4QE8Y@10239|Viruses,4QW3S@35237|dsDNA viruses  no RNA stage,4QPGZ@28883|Caudovirales	28883|Caudovirales	S	Recombination, repair and ssDNA binding protein UvsY	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_14856_1	1333523.L593_00420	9.69e-26	107.0	arCOG03850@1|root,arCOG03850@2157|Archaea,2XZTT@28890|Euryarchaeota,23Y39@183963|Halobacteria	183963|Halobacteria	S	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_24
k59_165522_1	1121405.dsmv_1683	1.38e-139	413.0	COG0511@1|root,COG5016@1|root,COG0511@2|Bacteria,COG5016@2|Bacteria,1QTTG@1224|Proteobacteria,43BUE@68525|delta/epsilon subdivisions,2X75I@28221|Deltaproteobacteria,2MPKE@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Conserved carboxylase domain	oadA	-	2.1.3.1,4.1.1.3,6.4.1.1	ko:K01571,ko:K01960,ko:K03416	ko00020,ko00620,ko00640,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00640,map00720,map01100,map01120,map01200,map01230	M00173,M00620	R00217,R00344,R00353,R00930	RC00040,RC00097,RC00367	ko00000,ko00001,ko00002,ko01000,ko02000	3.B.1.1.1	-	-	Biotin_lipoyl,HMGL-like,PYC_OADA
k59_51917_1	633148.Tagg_0352	6.99e-19	85.9	COG4720@1|root,arCOG05752@2157|Archaea,2XQ9C@28889|Crenarchaeota	28889|Crenarchaeota	S	ECF-type riboflavin transporter, S component	-	-	-	-	-	-	-	-	-	-	-	-	ECF-ribofla_trS
k59_28937_1	657309.BXY_08580	2.52e-72	229.0	29XC7@1|root,30J1Z@2|Bacteria,4PMTX@976|Bacteroidetes,2FR7E@200643|Bacteroidia,4APEM@815|Bacteroidaceae	976|Bacteroidetes	S	Domain of unknown function (DUF3560)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3560
k59_234681_1	690850.Desaf_3651	1.31e-67	217.0	COG0123@1|root,COG0123@2|Bacteria,1MU7P@1224|Proteobacteria,42V54@68525|delta/epsilon subdivisions,2WSDI@28221|Deltaproteobacteria,2MEEC@213115|Desulfovibrionales	28221|Deltaproteobacteria	BQ	Histone deacetylase domain	-	-	3.5.1.98	ko:K11418	ko05034,ko05165,ko05203,map05034,map05165,map05203	-	-	-	ko00000,ko00001,ko01000,ko03036	-	-	-	Hist_deacetyl
k59_204049_1	335543.Sfum_1829	5.79e-45	165.0	COG1924@1|root,COG3580@1|root,COG1924@2|Bacteria,COG3580@2|Bacteria,1PKG6@1224|Proteobacteria,42MY4@68525|delta/epsilon subdivisions,2WJFI@28221|Deltaproteobacteria,2MQ8R@213462|Syntrophobacterales	28221|Deltaproteobacteria	I	BadF BadG BcrA BcrD	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG,DUF2229
k59_37311_1	1121405.dsmv_2430	3.43e-104	310.0	COG2255@1|root,COG2255@2|Bacteria,1MU38@1224|Proteobacteria,42M99@68525|delta/epsilon subdivisions,2WJ2Q@28221|Deltaproteobacteria,2MHYU@213118|Desulfobacterales	28221|Deltaproteobacteria	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	-	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
k59_5815_1	335543.Sfum_4058	6.71e-104	312.0	COG0123@1|root,COG0123@2|Bacteria,1MU7P@1224|Proteobacteria,42MY3@68525|delta/epsilon subdivisions,2WJEF@28221|Deltaproteobacteria,2MQYA@213462|Syntrophobacterales	28221|Deltaproteobacteria	BQ	Histone deacetylase domain	-	-	-	ko:K04768	-	-	-	-	ko00000	-	-	-	Hist_deacetyl
k59_90198_1	340099.Teth39_2037	1.36e-134	399.0	COG3344@1|root,COG3344@2|Bacteria,1TP9A@1239|Firmicutes,248M4@186801|Clostridia,42EZK@68295|Thermoanaerobacterales	186801|Clostridia	L	PFAM RNA-directed DNA polymerase (Reverse transcriptase)	-	-	2.7.7.49	ko:K00986	-	-	-	-	ko00000,ko01000	-	-	-	GIIM,RVT_1
k59_44208_1	933262.AXAM01000062_gene945	3.82e-85	270.0	COG0741@1|root,COG1388@1|root,COG0741@2|Bacteria,COG1388@2|Bacteria,1MWKE@1224|Proteobacteria,42M5C@68525|delta/epsilon subdivisions,2WJ54@28221|Deltaproteobacteria,2MJ3U@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Lytic transglycosylase catalytic	mltD2	-	-	ko:K08307	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	LysM,SLT
k59_28962_1	439235.Dalk_1508	1.51e-130	380.0	COG2801@1|root,COG2801@2|Bacteria,1MVC8@1224|Proteobacteria,42NJR@68525|delta/epsilon subdivisions,2WKAM@28221|Deltaproteobacteria,2MJHK@213118|Desulfobacterales	28221|Deltaproteobacteria	L	Integrase core domain	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,HTH_Tnp_1,rve,rve_3
k59_165541_1	316067.Geob_3692	8.12e-98	301.0	COG2204@1|root,COG2204@2|Bacteria,1PAPS@1224|Proteobacteria,42NMK@68525|delta/epsilon subdivisions,2WK6K@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Sigma-54 factor interaction domain-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
k59_165541_2	880072.Desac_1024	2.24e-64	211.0	COG0477@1|root,COG2814@2|Bacteria,1MVSH@1224|Proteobacteria,42NA4@68525|delta/epsilon subdivisions,2WKTU@28221|Deltaproteobacteria,2MQRV@213462|Syntrophobacterales	28221|Deltaproteobacteria	EGP	PFAM Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
k59_105575_1	1219084.AP014508_gene692	1.57e-08	58.9	COG0549@1|root,COG0549@2|Bacteria,2GCB0@200918|Thermotogae	200918|Thermotogae	E	Belongs to the carbamate kinase family	-	-	2.7.2.2	ko:K00926	ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200	-	R00150,R01395	RC00002,RC00043,RC02803,RC02804	ko00000,ko00001,ko01000	-	-	-	AA_kinase
k59_44211_1	483215.BACFIN_07400	4.65e-62	206.0	COG3547@1|root,COG3547@2|Bacteria,4NHYP@976|Bacteroidetes,2FKYS@200643|Bacteroidia	976|Bacteroidetes	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_173585_1	96561.Dole_1465	1.64e-65	218.0	COG1018@1|root,COG3894@1|root,COG1018@2|Bacteria,COG3894@2|Bacteria,1MV6C@1224|Proteobacteria,42MF5@68525|delta/epsilon subdivisions,2WKC6@28221|Deltaproteobacteria,2MI4B@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Domain of unknown function (DUF4445)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4445,Fer2
k59_113101_1	1317122.ATO12_03100	1.86e-09	58.5	COG1280@1|root,COG1280@2|Bacteria,4NMHH@976|Bacteroidetes,1I1HP@117743|Flavobacteriia,2YIK9@290174|Aquimarina	976|Bacteroidetes	E	LysE type translocator	-	-	-	-	-	-	-	-	-	-	-	-	LysE
k59_113101_2	1041159.AZUW01000009_gene4472	1.64e-05	48.5	COG1834@1|root,COG1834@2|Bacteria,1MZ9U@1224|Proteobacteria,2TT08@28211|Alphaproteobacteria,4BDPT@82115|Rhizobiaceae	28211|Alphaproteobacteria	E	Amidinotransferase	-	-	3.5.3.18	ko:K01482	-	-	-	-	ko00000,ko01000,ko04147	-	-	-	Amidinotransf
k59_74953_1	1232410.KI421421_gene3869	5.79e-80	249.0	COG0849@1|root,COG0849@2|Bacteria,1MUSR@1224|Proteobacteria,42MS2@68525|delta/epsilon subdivisions,2WIQ0@28221|Deltaproteobacteria,43SXW@69541|Desulfuromonadales	28221|Deltaproteobacteria	D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring	ftsA	-	-	ko:K03590	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036,ko04812	-	-	-	FtsA,SHS2_FTSA
k59_226495_1	1123228.AUIH01000004_gene1103	4.99e-09	63.2	COG0584@1|root,COG0584@2|Bacteria,1MU8H@1224|Proteobacteria,1RQWX@1236|Gammaproteobacteria,1XRNV@135619|Oceanospirillales	135619|Oceanospirillales	C	Glycerophosphoryl diester phosphodiesterase family	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD,GPDPase_memb
k59_5832_1	290317.Cpha266_1840	1.25e-44	165.0	COG0457@1|root,COG3914@1|root,COG0457@2|Bacteria,COG3914@2|Bacteria	2|Bacteria	O	protein N-acetylglucosaminyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_41,TPR_1,TPR_11,TPR_16,TPR_2,TPR_4,TPR_8
k59_242048_1	911045.PSE_3738	7.09e-19	79.3	29ZH6@1|root,30MGX@2|Bacteria,1Q4G5@1224|Proteobacteria,2UN38@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Protein of unknown function (DUF1656)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1656
k59_242048_2	113395.AXAI01000001_gene3185	6.58e-22	96.3	COG1289@1|root,COG1289@2|Bacteria,1Q5JG@1224|Proteobacteria,2VBX6@28211|Alphaproteobacteria,3K2KA@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Aromatic acid exporter family member 1	-	-	-	-	-	-	-	-	-	-	-	-	FUSC
k59_52619_1	706587.Desti_2807	2.3e-74	232.0	COG0535@1|root,COG0535@2|Bacteria,1MU07@1224|Proteobacteria,42QKH@68525|delta/epsilon subdivisions,2WMW7@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM Radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF3641,Fer4_12,Radical_SAM
k59_166134_1	883.DvMF_2266	3.68e-75	241.0	COG3608@1|root,COG3608@2|Bacteria,1Q5G3@1224|Proteobacteria,42MSH@68525|delta/epsilon subdivisions,2WKM8@28221|Deltaproteobacteria,2M8TP@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	PFAM Succinylglutamate desuccinylase Aspartoacylase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M99,Peptidase_M99_C
k59_174183_1	1121405.dsmv_3267	4.88e-94	290.0	COG1530@1|root,COG1530@2|Bacteria,1MV65@1224|Proteobacteria,42M5E@68525|delta/epsilon subdivisions,2WIV6@28221|Deltaproteobacteria,2MISJ@213118|Desulfobacterales	28221|Deltaproteobacteria	J	ribonuclease Rne Rng family	cafA	-	3.1.26.12	ko:K08300,ko:K08301	ko03018,map03018	M00394	-	-	ko00000,ko00001,ko00002,ko01000,ko03009,ko03019	-	-	-	RNase_E_G,S1
k59_52633_1	1121405.dsmv_0959	5.24e-11	62.4	COG1530@1|root,COG1530@2|Bacteria,1MV65@1224|Proteobacteria,42M5E@68525|delta/epsilon subdivisions,2WIV6@28221|Deltaproteobacteria,2MIDU@213118|Desulfobacterales	28221|Deltaproteobacteria	J	TIGRFAM ribonuclease, Rne Rng family	rne	-	3.1.26.12	ko:K08300,ko:K08301	ko03018,map03018	M00394	-	-	ko00000,ko00001,ko00002,ko01000,ko03009,ko03019	-	-	-	RNase_E_G,S1
k59_166142_1	314285.KT71_07424	7.82e-25	101.0	2E61B@1|root,330QK@2|Bacteria,1N39M@1224|Proteobacteria,1SMYA@1236|Gammaproteobacteria,1J9DI@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_227086_1	1380354.JIAN01000005_gene2303	1.05e-26	105.0	COG1136@1|root,COG1136@2|Bacteria,2GJQV@201174|Actinobacteria	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
k59_121247_2	1276920.ADIAG_02353	4.07e-06	52.0	COG4447@1|root,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,FIVAR,Flg_new,Metallophos,PSII_BNR,SLH,TIG
k59_174185_2	595494.Tola_1244	1.2e-66	210.0	COG2834@1|root,COG2834@2|Bacteria,1R5CY@1224|Proteobacteria,1T0NP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Outer membrane lipoprotein-sorting protein	-	-	-	-	-	-	-	-	-	-	-	-	LolA_like
k59_98351_2	671143.DAMO_1295	1.31e-84	257.0	COG4422@1|root,COG4422@2|Bacteria	2|Bacteria	F	Protein of unknown function (DUF5131)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5131
k59_219450_1	941449.dsx2_1701	3.11e-60	197.0	COG0303@1|root,COG0303@2|Bacteria,1QUKM@1224|Proteobacteria,42NTF@68525|delta/epsilon subdivisions,2WKN1@28221|Deltaproteobacteria,2M95Q@213115|Desulfovibrionales	28221|Deltaproteobacteria	H	PFAM molybdopterin binding	-	-	-	-	-	-	-	-	-	-	-	-	MoCF_biosynth
k59_151009_1	1121405.dsmv_2611	4.04e-76	248.0	COG0603@1|root,COG1402@1|root,COG0603@2|Bacteria,COG1402@2|Bacteria,1MXR9@1224|Proteobacteria,42QNA@68525|delta/epsilon subdivisions,2X9RQ@28221|Deltaproteobacteria,2MPA0@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Creatinine amidohydrolase	-	-	3.5.2.10	ko:K01470	ko00330,map00330	-	R01884	RC00615	ko00000,ko00001,ko01000	-	-	-	Creatininase
k59_29735_2	706587.Desti_3172	1.13e-123	361.0	COG0714@1|root,COG0714@2|Bacteria,1MV5I@1224|Proteobacteria,42Q8T@68525|delta/epsilon subdivisions,2WKQE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	AAA domain (dynein-related subfamily)	-	-	-	-	-	-	-	-	-	-	-	-	AAA_5
k59_29736_1	1536769.P40081_20890	7.69e-17	83.6	COG1011@1|root,COG1011@2|Bacteria,1VDD7@1239|Firmicutes,4ISJ7@91061|Bacilli,27743@186822|Paenibacillaceae	91061|Bacilli	S	haloacid dehalogenase-like hydrolase	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2
k59_67720_1	936136.ARRT01000003_gene6157	5.9e-07	58.2	COG0451@1|root,COG0451@2|Bacteria,1MXKV@1224|Proteobacteria,2TRM0@28211|Alphaproteobacteria,4BA55@82115|Rhizobiaceae	28211|Alphaproteobacteria	GM	dTDP-glucose 4-6-dehydratase	-	-	4.1.1.35	ko:K08678	ko00520,ko01100,map00520,map01100	M00361	R01384	RC00508	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
k59_98370_1	96561.Dole_2515	6.1e-86	266.0	COG0438@1|root,COG0438@2|Bacteria,1R8YI@1224|Proteobacteria,42N8I@68525|delta/epsilon subdivisions,2WIYJ@28221|Deltaproteobacteria,2MMJB@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
k59_242093_1	926556.Echvi_4187	5.61e-76	237.0	COG2801@1|root,COG2801@2|Bacteria,4NM64@976|Bacteroidetes,47PK2@768503|Cytophagia	976|Bacteroidetes	L	Integrase core domain	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	rve,rve_3
k59_196422_1	123214.PERMA_0817	6.04e-16	85.1	COG3156@1|root,COG3156@2|Bacteria,2G4SA@200783|Aquificae	200783|Aquificae	U	Type II secretion system (T2SS), protein K	-	-	-	ko:K02460	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSK
k59_29749_1	1121405.dsmv_3135	5.41e-87	270.0	COG1190@1|root,COG1190@2|Bacteria,1MX1V@1224|Proteobacteria,42M90@68525|delta/epsilon subdivisions,2WJ9G@28221|Deltaproteobacteria,2MHV2@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Belongs to the class-II aminoacyl-tRNA synthetase family	lysS	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
k59_98379_2	1121935.AQXX01000126_gene903	1.01e-24	105.0	COG0726@1|root,COG0726@2|Bacteria,1MVKH@1224|Proteobacteria,1RZ5C@1236|Gammaproteobacteria,1XMR2@135619|Oceanospirillales	135619|Oceanospirillales	G	Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
k59_121281_1	394503.Ccel_2977	1.18e-113	335.0	COG2801@1|root,COG2801@2|Bacteria,1V8EJ@1239|Firmicutes,24MA4@186801|Clostridia,36HTH@31979|Clostridiaceae	186801|Clostridia	L	PFAM Integrase catalytic region	-	-	-	-	-	-	-	-	-	-	-	-	HTH_29,HTH_8,rve
k59_29759_1	335543.Sfum_0294	1.05e-47	173.0	COG0591@1|root,COG1842@1|root,COG3852@1|root,COG0591@2|Bacteria,COG1842@2|Bacteria,COG3852@2|Bacteria,1NTTH@1224|Proteobacteria,43CEX@68525|delta/epsilon subdivisions,2X7PW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	SMART PAS domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	HisKA,PAS
k59_44944_1	1392491.JIAE01000001_gene1818	1.87e-19	93.6	COG3547@1|root,COG3547@2|Bacteria,1TQP6@1239|Firmicutes,248VD@186801|Clostridia,3WJ5B@541000|Ruminococcaceae	186801|Clostridia	L	Transposase IS116/IS110/IS902 family	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_196432_1	555778.Hneap_0412	1.54e-91	278.0	COG3335@1|root,COG3335@2|Bacteria,1MW7X@1224|Proteobacteria,1RRMU@1236|Gammaproteobacteria,1X26N@135613|Chromatiales	135613|Chromatiales	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,HTH_32
k59_6461_1	105559.Nwat_1968	5.2e-43	161.0	COG0457@1|root,COG3712@1|root,COG0457@2|Bacteria,COG3712@2|Bacteria,1RJUD@1224|Proteobacteria,1S0ET@1236|Gammaproteobacteria	1236|Gammaproteobacteria	PT	FecR protein	-	-	-	-	-	-	-	-	-	-	-	-	FecR,TPR_16,TPR_19,TonB_dep_Rec
k59_151049_1	1333856.L686_21250	7.24e-05	47.8	COG3063@1|root,COG3063@2|Bacteria,1N2T8@1224|Proteobacteria,1S9R8@1236|Gammaproteobacteria,1Z2ZQ@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	NU	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_14,TPR_16,TPR_19,TPR_2
k59_151049_2	926690.KE386573_gene644	8.13e-20	89.7	COG1171@1|root,arCOG01431@2157|Archaea,2XT4W@28890|Euryarchaeota,23SNZ@183963|Halobacteria	183963|Halobacteria	E	Threonine dehydratase	ilvA1	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT_4,PALP
k59_121293_1	156889.Mmc1_0331	6.87e-50	183.0	COG0784@1|root,COG0834@1|root,COG4251@1|root,COG0784@2|Bacteria,COG0834@2|Bacteria,COG4251@2|Bacteria,1NC9X@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	luxQ	GO:0000155,GO:0000160,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0035556,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0071704,GO:0140096,GO:1901564	2.7.13.3	ko:K07678,ko:K10909	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	M00475,M00513	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,Hpt,LuxQ-periplasm,PAS,PAS_3,PAS_9,Response_reg,SBP_bac_3,dCache_1
k59_151056_1	56780.SYN_02535	7.71e-65	215.0	COG0173@1|root,COG0173@2|Bacteria,1MUXB@1224|Proteobacteria,42NC6@68525|delta/epsilon subdivisions,2WJEV@28221|Deltaproteobacteria,2MR5T@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
k59_196445_2	596330.HMPREF0628_0682	1.22e-09	63.9	COG0419@1|root,COG0419@2|Bacteria,1V1S1@1239|Firmicutes,24FUH@186801|Clostridia,22INU@1570339|Peptoniphilaceae	186801|Clostridia	L	AAA domain	-	-	-	ko:K03546	-	-	-	-	ko00000,ko03400	-	-	-	AAA_15,AAA_23,Rad50_zn_hook
k59_181361_1	1089552.KI911559_gene3197	1.93e-42	152.0	COG0564@1|root,COG0564@2|Bacteria,1MUBN@1224|Proteobacteria,2TSBK@28211|Alphaproteobacteria,2JQ4Y@204441|Rhodospirillales	204441|Rhodospirillales	J	Responsible for synthesis of pseudouridine from uracil	rluD	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
k59_52698_1	706587.Desti_5240	2.16e-14	75.5	COG0382@1|root,COG0761@1|root,COG0382@2|Bacteria,COG0761@2|Bacteria,1MU7G@1224|Proteobacteria,42MJK@68525|delta/epsilon subdivisions,2WJ8V@28221|Deltaproteobacteria,2MQH4@213462|Syntrophobacterales	28221|Deltaproteobacteria	IM	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis	ispH	-	1.17.7.4	ko:K02945,ko:K03527	ko00900,ko01100,ko01110,ko01130,ko03010,map00900,map01100,map01110,map01130,map03010	M00096,M00178	R05884,R08210	RC01137,RC01487	br01610,ko00000,ko00001,ko00002,ko01000,ko03011	-	-	-	LYTB,UbiA
k59_52698_2	398767.Glov_2347	1.24e-13	73.2	COG1216@1|root,COG1442@1|root,COG1216@2|Bacteria,COG1442@2|Bacteria,1PFT2@1224|Proteobacteria,439ZB@68525|delta/epsilon subdivisions,2XA08@28221|Deltaproteobacteria,43VGB@69541|Desulfuromonadales	2|Bacteria	M	Glycosyl transferase, family 2	yfnF	-	2.4.1.83	ko:K00721,ko:K07011,ko:K20444	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003,ko01005,ko02000	4.D.1.3	GT2,GT4	-	Glycos_transf_2,Nucleotid_trans
k59_151074_1	350688.Clos_1947	2.68e-40	142.0	COG0225@1|root,COG0225@2|Bacteria,1TQ3E@1239|Firmicutes	1239|Firmicutes	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	-	1.8.4.11,1.8.4.12	ko:K07304,ko:K12267	-	-	-	-	ko00000,ko01000	-	-	-	PMSR,SelR
k59_227149_1	879212.DespoDRAFT_00345	3.28e-108	334.0	COG1129@1|root,COG1129@2|Bacteria,1QTT9@1224|Proteobacteria,43BJ5@68525|delta/epsilon subdivisions,2X713@28221|Deltaproteobacteria,2MPNG@213118|Desulfobacterales	28221|Deltaproteobacteria	G	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
k59_52701_1	1125863.JAFN01000001_gene3444	1.19e-57	190.0	COG0683@1|root,COG0683@2|Bacteria,1MWJ1@1224|Proteobacteria,42Q41@68525|delta/epsilon subdivisions,2WK4A@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	PFAM Extracellular ligand-binding receptor	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
k59_29800_1	1122194.AUHU01000003_gene2356	2.76e-06	53.5	COG0845@1|root,COG0845@2|Bacteria,1PEVY@1224|Proteobacteria,1RPEQ@1236|Gammaproteobacteria,465PN@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3
k59_174259_1	1121405.dsmv_0309	2e-123	359.0	COG1082@1|root,COG1082@2|Bacteria,1N95R@1224|Proteobacteria,42RAA@68525|delta/epsilon subdivisions,2WN55@28221|Deltaproteobacteria,2MJEW@213118|Desulfobacterales	28221|Deltaproteobacteria	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
k59_22293_1	56780.SYN_00324	1.68e-80	247.0	COG1633@1|root,COG1633@2|Bacteria	2|Bacteria	S	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)	-	-	1.16.3.1	ko:K03594	ko00860,map00860	-	R00078	RC02758	ko00000,ko00001,ko01000	-	-	-	Ferritin,POR,Rubrerythrin
k59_44989_1	1232437.KL662020_gene705	3.02e-83	260.0	COG3547@1|root,COG3547@2|Bacteria	2|Bacteria	L	Transposase (IS116 IS110 IS902 family)	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_196471_1	257310.BB1452	4.38e-31	130.0	COG1178@1|root,COG1178@2|Bacteria,1R0MN@1224|Proteobacteria,2VK7P@28216|Betaproteobacteria,3T76X@506|Alcaligenaceae	28216|Betaproteobacteria	P	ABC-type Fe3 transport system permease component	-	-	-	ko:K02011	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	BPD_transp_1
k59_44991_1	283699.D172_4157	7.79e-115	343.0	COG3547@1|root,COG3547@2|Bacteria,1NGR7@1224|Proteobacteria,1RMF9@1236|Gammaproteobacteria,2Q4E4@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	L	Transposase IS116/IS110/IS902 family	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_98446_1	706587.Desti_5099	4.53e-80	249.0	COG0697@1|root,COG0697@2|Bacteria,1MUQ7@1224|Proteobacteria,42R74@68525|delta/epsilon subdivisions,2WMRT@28221|Deltaproteobacteria,2MRGD@213462|Syntrophobacterales	28221|Deltaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
k59_151099_2	706587.Desti_1705	2.38e-30	110.0	COG2840@1|root,COG2840@2|Bacteria,1QX48@1224|Proteobacteria,43BWQ@68525|delta/epsilon subdivisions,2X77I@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Smr domain	-	-	-	-	-	-	-	-	-	-	-	-	Smr
k59_224885_1	1487953.JMKF01000002_gene537	2.41e-136	408.0	COG0280@1|root,COG0857@1|root,COG0280@2|Bacteria,COG0857@2|Bacteria,1G16R@1117|Cyanobacteria,1H85V@1150|Oscillatoriales	1117|Cyanobacteria	C	belongs to the CobB CobQ family	pta	-	2.3.1.8	ko:K13788	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00230,R00921	RC00004,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_26,DRTGG,PTA_PTB
k59_13376_1	671143.DAMO_3066	7.65e-64	213.0	COG0318@1|root,COG0318@2|Bacteria,2NQWW@2323|unclassified Bacteria	2|Bacteria	IQ	AMP-binding enzyme	JD73_00810	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C_2
k59_20284_1	63737.Npun_F3600	1.49e-05	52.8	COG1136@1|root,COG1136@2|Bacteria,1G1SM@1117|Cyanobacteria,1HIMY@1161|Nostocales	1117|Cyanobacteria	V	TIGRFAM ABC exporter ATP-binding subunit, DevA family	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
k59_20284_2	1121949.AQXT01000002_gene474	0.00012	47.8	COG0767@1|root,COG0767@2|Bacteria,1MVPN@1224|Proteobacteria,2TSGS@28211|Alphaproteobacteria,43WM1@69657|Hyphomonadaceae	28211|Alphaproteobacteria	Q	COG0767 ABC-type transport system involved in resistance to organic solvents, permease component	mlaE	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
k59_35989_1	1167006.UWK_01188	2.53e-64	200.0	COG2316@1|root,COG2316@2|Bacteria,1RA50@1224|Proteobacteria,42QZZ@68525|delta/epsilon subdivisions,2WMUN@28221|Deltaproteobacteria,2MJHQ@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	-	-	-	-	-	-	-	-	-	HD
k59_233300_1	1121935.AQXX01000127_gene1206	1.14e-37	135.0	COG2062@1|root,COG2062@2|Bacteria,1RIC8@1224|Proteobacteria,1S9AU@1236|Gammaproteobacteria,1XPNN@135619|Oceanospirillales	135619|Oceanospirillales	T	Phosphoglycerate mutase	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
k59_148867_2	404589.Anae109_3527	8.01e-35	134.0	COG1360@1|root,COG1360@2|Bacteria	2|Bacteria	N	Flagellar Motor Protein	motB	-	-	ko:K02557	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	OmpA
k59_36000_1	667014.Thein_1207	1.5e-66	207.0	COG0669@1|root,COG0669@2|Bacteria,2GHAF@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	H	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	-	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
k59_233301_2	1265505.ATUG01000002_gene1229	6.96e-47	156.0	COG1100@1|root,COG1100@2|Bacteria,1RIAW@1224|Proteobacteria,42W3E@68525|delta/epsilon subdivisions,2WVMV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Ras of Complex, Roc, domain of DAPkinase	-	-	-	-	-	-	-	-	-	-	-	-	Ras
k59_187833_1	1379698.RBG1_1C00001G1520	1.33e-52	179.0	COG1104@1|root,COG1104@2|Bacteria,2NNVR@2323|unclassified Bacteria	2|Bacteria	E	Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
k59_217539_1	335543.Sfum_1795	3.95e-86	270.0	COG3383@1|root,COG3383@2|Bacteria,1QTZB@1224|Proteobacteria,42SPZ@68525|delta/epsilon subdivisions,2WIV9@28221|Deltaproteobacteria,2MRHE@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Fer2_4,Fer4_7,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
k59_4536_1	933262.AXAM01000033_gene1644	1.38e-50	173.0	COG2069@1|root,COG2069@2|Bacteria,1QS8G@1224|Proteobacteria,437H2@68525|delta/epsilon subdivisions,2WKVX@28221|Deltaproteobacteria,2MI1T@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM CO dehydrogenase acetyl-CoA synthase delta subunit	-	-	2.1.1.245	ko:K00194	ko00680,ko00720,ko01120,ko01200,map00680,map00720,map01120,map01200	M00357,M00377,M00422	R09096,R10219,R10243	RC00004,RC00113,RC02977	ko00000,ko00001,ko00002,ko01000	-	-	-	CdhD
k59_4537_1	1122247.C731_4959	8.42e-16	77.8	COG1522@1|root,COG1522@2|Bacteria,2HSQU@201174|Actinobacteria,23DK3@1762|Mycobacteriaceae	201174|Actinobacteria	K	helix_turn_helix ASNC type	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg,HTH_AsnC-type
k59_194374_1	1121403.AUCV01000056_gene3012	6.62e-144	427.0	COG0661@1|root,COG0661@2|Bacteria,1MU1Z@1224|Proteobacteria,42N87@68525|delta/epsilon subdivisions,2WK1B@28221|Deltaproteobacteria,2MHU5@213118|Desulfobacterales	28221|Deltaproteobacteria	S	pfam abc-1	-	-	-	ko:K03688	-	-	-	-	ko00000	-	-	-	ABC1,APH
k59_172280_1	472759.Nhal_1494	2.33e-53	176.0	COG0224@1|root,COG0224@2|Bacteria,1QUME@1224|Proteobacteria,1S2EG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	WbqC-like protein family	-	-	-	-	-	-	-	-	-	-	-	-	WbqC
k59_111577_1	290318.Cvib_1086	2.25e-22	90.9	COG0713@1|root,COG0713@2|Bacteria,1FE6D@1090|Chlorobi	1090|Chlorobi	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoK	-	1.6.5.3	ko:K00340	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q2
k59_111577_2	1121422.AUMW01000002_gene2164	8.01e-17	79.3	COG0839@1|root,COG0839@2|Bacteria,1VAQI@1239|Firmicutes,24NAC@186801|Clostridia,2626F@186807|Peptococcaceae	186801|Clostridia	C	Belongs to the complex I subunit 6 family	ndhG	-	1.6.5.3	ko:K00339,ko:K05578	ko00190,ko01100,map00190,map01100	M00144,M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q3
k59_118676_1	1232410.KI421423_gene1924	1.99e-144	425.0	COG2414@1|root,COG2414@2|Bacteria,1R9KF@1224|Proteobacteria,42PQB@68525|delta/epsilon subdivisions,2WKS3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Aldehyde ferredoxin oxidoreductase, N-terminal domain	-	-	1.2.7.5	ko:K03738	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00309	R08571	RC00242	ko00000,ko00001,ko00002,ko01000	-	-	-	AFOR_C,AFOR_N
k59_118677_1	335543.Sfum_0463	1.08e-31	116.0	2ECCP@1|root,336AZ@2|Bacteria,1N9PN@1224|Proteobacteria,42W93@68525|delta/epsilon subdivisions,2WRXB@28221|Deltaproteobacteria,2MS3Z@213462|Syntrophobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Rho_N
k59_118677_2	706587.Desti_4731	1.43e-37	132.0	COG2316@1|root,COG2316@2|Bacteria,1RA50@1224|Proteobacteria,42QZZ@68525|delta/epsilon subdivisions,2WMUN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM Metal-dependent phosphohydrolase, HD	-	-	-	ko:K06951	-	-	-	-	ko00000	-	-	-	HD
k59_20320_1	1232410.KI421419_gene2478	1.58e-77	249.0	COG1048@1|root,COG1048@2|Bacteria,1MU9T@1224|Proteobacteria,42N5M@68525|delta/epsilon subdivisions,2WIIV@28221|Deltaproteobacteria,43RYP@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Aconitase C-terminal domain	-	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2763	Aconitase,Aconitase_C
k59_81444_1	935836.JAEL01000007_gene2880	1.2e-53	181.0	COG4177@1|root,COG4177@2|Bacteria,1TPMZ@1239|Firmicutes,4HBB8@91061|Bacilli,1ZBKN@1386|Bacillus	91061|Bacilli	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
k59_164297_1	335543.Sfum_0019	1.47e-22	94.7	COG2014@1|root,COG2014@2|Bacteria,1RGNW@1224|Proteobacteria,42RPF@68525|delta/epsilon subdivisions,2WNJQ@28221|Deltaproteobacteria,2MRP2@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Putative heavy-metal chelation	-	-	-	ko:K09138	-	-	-	-	ko00000	-	-	-	DUF364,DUF4213
k59_164297_2	269799.Gmet_0302	3.63e-61	192.0	COG2258@1|root,COG2258@2|Bacteria,1RKJ9@1224|Proteobacteria,42TCU@68525|delta/epsilon subdivisions,2WP56@28221|Deltaproteobacteria,43UTW@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	MOSC domain	-	-	-	-	-	-	-	-	-	-	-	iAF987.Gmet_0302	MOSC
k59_164300_1	1121405.dsmv_0994	6.3e-31	122.0	COG0589@1|root,COG0589@2|Bacteria,1RF1N@1224|Proteobacteria,42S7A@68525|delta/epsilon subdivisions,2WNZK@28221|Deltaproteobacteria,2MKM5@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
k59_217573_2	1121374.KB891580_gene1808	6.05e-28	113.0	COG1119@1|root,COG1119@2|Bacteria,1MVVM@1224|Proteobacteria,1RMXK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	ABC-type molybdenum transport system ATPase component photorepair protein PhrA	modF	GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0008144,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363	3.6.3.34	ko:K02013,ko:K05776	ko02010,map02010	M00189,M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	ABC_tran
k59_36024_1	1121405.dsmv_1463	3.42e-44	159.0	COG0404@1|root,COG0446@1|root,COG0404@2|Bacteria,COG0446@2|Bacteria,1MVEK@1224|Proteobacteria,42P3Z@68525|delta/epsilon subdivisions,2WKRN@28221|Deltaproteobacteria,2MJ14@213118|Desulfobacterales	28221|Deltaproteobacteria	C	2Fe-2S iron-sulfur cluster binding domain	-	-	1.5.3.1	ko:K00302	ko00260,ko01100,map00260,map01100	-	R00610	RC00060,RC00557	ko00000,ko00001,ko01000	-	-	-	Fer2_4,Fer2_BFD,GCV_T,GCV_T_C,Pyr_redox_2
k59_36024_2	1121405.dsmv_1462	9.92e-56	173.0	COG4311@1|root,COG4311@2|Bacteria,1Q23E@1224|Proteobacteria,42UXF@68525|delta/epsilon subdivisions,2WR1S@28221|Deltaproteobacteria,2MKEP@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Sarcosine oxidase, delta subunit family	-	-	1.5.3.1	ko:K00304	ko00260,ko01100,map00260,map01100	-	R00610	RC00060,RC00557	ko00000,ko00001,ko01000	-	-	-	SoxD
k59_36024_3	1121405.dsmv_1461	5.01e-12	64.7	COG0665@1|root,COG0665@2|Bacteria,1MVM6@1224|Proteobacteria,42NTX@68525|delta/epsilon subdivisions,2WMFG@28221|Deltaproteobacteria,2MITC@213118|Desulfobacterales	28221|Deltaproteobacteria	E	FAD dependent oxidoreductase	soxB	-	1.5.3.1	ko:K00303	ko00260,ko01100,map00260,map01100	-	R00610	RC00060,RC00557	ko00000,ko00001,ko01000	-	-	-	DAO,Fer2_BFD
k59_13424_1	335543.Sfum_1178	6.2e-82	257.0	COG1148@1|root,COG1148@2|Bacteria,1PH3R@1224|Proteobacteria,42PTD@68525|delta/epsilon subdivisions,2WIZ5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	4fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Pyr_redox_2
k59_65670_1	1121403.AUCV01000056_gene3012	4.65e-99	308.0	COG0661@1|root,COG0661@2|Bacteria,1MU1Z@1224|Proteobacteria,42N87@68525|delta/epsilon subdivisions,2WK1B@28221|Deltaproteobacteria,2MHU5@213118|Desulfobacterales	28221|Deltaproteobacteria	S	pfam abc-1	-	-	-	ko:K03688	-	-	-	-	ko00000	-	-	-	ABC1,APH
k59_194393_1	1232437.KL661954_gene2354	2.91e-36	131.0	COG1414@1|root,COG1414@2|Bacteria,1MUNW@1224|Proteobacteria,42M2F@68525|delta/epsilon subdivisions,2WKUG@28221|Deltaproteobacteria,2MM3S@213118|Desulfobacterales	28221|Deltaproteobacteria	K	helix_turn_helix isocitrate lyase regulation	-	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR,IclR
k59_240011_1	1433126.BN938_1386	4.54e-37	131.0	COG1238@1|root,COG1238@2|Bacteria,4PIJW@976|Bacteroidetes,2G1VB@200643|Bacteroidia,22V72@171550|Rikenellaceae	976|Bacteroidetes	S	SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
k59_58920_2	573413.Spirs_3930	1.58e-74	225.0	COG0454@1|root,COG0456@2|Bacteria,2J948@203691|Spirochaetes	203691|Spirochaetes	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_10
k59_194395_1	1379281.AVAG01000031_gene106	1.88e-95	307.0	COG0506@1|root,COG1012@1|root,COG0506@2|Bacteria,COG1012@2|Bacteria,1MV93@1224|Proteobacteria,42MQH@68525|delta/epsilon subdivisions,2WJPV@28221|Deltaproteobacteria,2M8WP@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	Oxidizes proline to glutamate for use as a carbon and nitrogen source	putA	-	1.2.1.88,1.5.5.2	ko:K13821	ko00250,ko00330,ko01100,ko01110,ko01130,map00250,map00330,map01100,map01110,map01130	-	R00245,R00707,R00708,R01253,R04444,R04445,R05051	RC00080,RC00083,RC00216,RC00242,RC00255	ko00000,ko00001,ko01000,ko03000	-	-	iAF987.Gmet_3512	Aldedh,Pro_dh
k59_81453_1	1123355.JHYO01000012_gene666	2.99e-127	374.0	COG3181@1|root,COG3181@2|Bacteria,1MWVK@1224|Proteobacteria,2TXW7@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
k59_157195_1	335543.Sfum_0862	2.16e-09	58.5	COG0683@1|root,COG0683@2|Bacteria,1MWJ1@1224|Proteobacteria,42MSJ@68525|delta/epsilon subdivisions,2WKHJ@28221|Deltaproteobacteria,2MQYJ@213462|Syntrophobacterales	28221|Deltaproteobacteria	E	Receptor family ligand binding region	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
k59_157195_2	796942.HMPREF9623_00110	6.03e-08	62.0	COG0683@1|root,COG0683@2|Bacteria,1TPQ2@1239|Firmicutes,248H1@186801|Clostridia	186801|Clostridia	E	PFAM Extracellular ligand-binding receptor	braC	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
k59_217589_1	635013.TherJR_2237	5.82e-19	82.8	COG2005@1|root,COG2005@2|Bacteria	2|Bacteria	P	Transcriptional regulator	-	-	-	ko:K02019,ko:K05772	ko02010,map02010	M00186	-	-	ko00000,ko00001,ko00002,ko02000,ko03000	3.A.1.6.2,3.A.1.6.4	-	-	HTH_1,PBP_like_2
k59_96444_1	1121405.dsmv_0483	3.77e-137	402.0	COG1418@1|root,COG1418@2|Bacteria,1P7YA@1224|Proteobacteria,42KZ8@68525|delta/epsilon subdivisions,2WJG1@28221|Deltaproteobacteria,2MHS7@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Endoribonuclease that initiates mRNA decay	rny	-	-	ko:K18682	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DUF3552,HD,KH_1
k59_118705_1	526222.Desal_1836	4.01e-58	197.0	COG0272@1|root,COG0272@2|Bacteria,1MV3R@1224|Proteobacteria,42MC5@68525|delta/epsilon subdivisions,2WIT5@28221|Deltaproteobacteria,2M8QF@213115|Desulfovibrionales	28221|Deltaproteobacteria	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	-	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
k59_118705_2	1121396.KB893057_gene2466	5.96e-19	79.0	2CGS2@1|root,32S4H@2|Bacteria,1N2GM@1224|Proteobacteria,42TM5@68525|delta/epsilon subdivisions,2WQTK@28221|Deltaproteobacteria,2MKF0@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_202779_1	649747.HMPREF0083_01770	7.27e-88	268.0	COG2043@1|root,COG2043@2|Bacteria,1TT5P@1239|Firmicutes,4HFED@91061|Bacilli,2729A@186822|Paenibacillaceae	91061|Bacilli	S	Uncharacterised ArCR, COG2043	-	-	-	-	-	-	-	-	-	-	-	-	DUF169
k59_13437_1	1320556.AVBP01000010_gene3291	1.2e-16	82.8	COG0559@1|root,COG0559@2|Bacteria,1N5XH@1224|Proteobacteria,2TSH5@28211|Alphaproteobacteria,43HPP@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	E	Belongs to the binding-protein-dependent transport system permease family	MA20_29495	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
k59_224954_1	1211035.CD30_06835	4.92e-14	77.4	COG3547@1|root,COG3547@2|Bacteria,1TQ5G@1239|Firmicutes,4HB35@91061|Bacilli,3IZBK@400634|Lysinibacillus	91061|Bacilli	L	Transposase IS116/IS110/IS902 family	-	-	-	ko:K07486	-	-	-	-	ko00000	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_202784_2	335543.Sfum_1469	8.39e-83	254.0	COG0191@1|root,COG0191@2|Bacteria,1MURX@1224|Proteobacteria,42MK7@68525|delta/epsilon subdivisions,2WJCJ@28221|Deltaproteobacteria,2MRHZ@213462|Syntrophobacterales	28221|Deltaproteobacteria	G	Fructose-bisphosphate aldolase class-II	fbaA	-	4.1.2.13	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167,M00344,M00345	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	F_bP_aldolase
k59_27641_1	880072.Desac_0680	5.77e-56	185.0	COG1237@1|root,COG1237@2|Bacteria,1NK2I@1224|Proteobacteria,42QRA@68525|delta/epsilon subdivisions,2WN1V@28221|Deltaproteobacteria,2MQMM@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Metallo-beta-lactamase superfamily	-	-	2.5.1.105	ko:K06897	ko00790,map00790	-	R10339	RC00121	ko00000,ko00001,ko01000	-	-	-	Lactamase_B
k59_240036_1	1232437.KL661988_gene188	2.99e-37	141.0	COG1624@1|root,COG1624@2|Bacteria,1PEQT@1224|Proteobacteria,42P5A@68525|delta/epsilon subdivisions,2WKPP@28221|Deltaproteobacteria,2MIQR@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DisA_N,YbbR
k59_194409_1	335543.Sfum_4046	2.72e-15	68.6	COG1146@1|root,COG1146@2|Bacteria,1QWQ4@1224|Proteobacteria,43BUY@68525|delta/epsilon subdivisions,2X75X@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_7
k59_194409_2	439235.Dalk_1202	2.13e-15	72.4	COG0346@1|root,COG0346@2|Bacteria,1PM7Y@1224|Proteobacteria,42RD3@68525|delta/epsilon subdivisions,2WNY7@28221|Deltaproteobacteria,2MJSI@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
k59_96464_1	177439.DP1083	6.49e-42	155.0	COG0768@1|root,COG0768@2|Bacteria,1MV8C@1224|Proteobacteria,42M1S@68525|delta/epsilon subdivisions,2WJ02@28221|Deltaproteobacteria,2MHV4@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Penicillin-binding Protein dimerisation domain	mrdA	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	iAF987.Gmet_0928	PBP_dimer,Transpeptidase
k59_111602_1	1232437.KL661978_gene3782	1.61e-27	114.0	COG2114@1|root,COG4252@1|root,COG2114@2|Bacteria,COG4252@2|Bacteria,1MV1V@1224|Proteobacteria,42N5S@68525|delta/epsilon subdivisions,2WIUS@28221|Deltaproteobacteria,2MJZH@213118|Desulfobacterales	28221|Deltaproteobacteria	T	CHASE2	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	CHASE2,Guanylate_cyc
k59_142215_1	1089453.GOSPT_022_00120	6.01e-14	72.8	COG0491@1|root,COG0491@2|Bacteria,2GJU0@201174|Actinobacteria,4GCA3@85026|Gordoniaceae	201174|Actinobacteria	S	Metallo-beta-lactamase superfamily	-	-	3.1.2.6	ko:K01069	ko00620,map00620	-	R01736	RC00004,RC00137	ko00000,ko00001,ko01000	-	-	-	Lactamase_B
k59_96465_1	644282.Deba_2132	1.1e-63	218.0	COG1148@1|root,COG1148@2|Bacteria,1QUM4@1224|Proteobacteria,42MPP@68525|delta/epsilon subdivisions,2WJ3U@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	4Fe-4S ferredoxin iron-sulfur binding domain protein	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_20,Fer4_4,Fer4_7,NAD_binding_8,Pyr_redox_2
k59_4571_1	644968.DFW101_0065	6.64e-48	170.0	COG0642@1|root,COG2205@2|Bacteria,1N17V@1224|Proteobacteria,42PVC@68525|delta/epsilon subdivisions,2WKU9@28221|Deltaproteobacteria,2M8FG@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
k59_210466_1	1121405.dsmv_2901	8.84e-75	234.0	COG1035@1|root,COG1146@1|root,COG1035@2|Bacteria,COG1146@2|Bacteria,1MWJC@1224|Proteobacteria,42QB3@68525|delta/epsilon subdivisions,2WM0Q@28221|Deltaproteobacteria,2MIXS@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM Coenzyme F420 hydrogenase dehydrogenase, beta subunit	-	-	1.12.98.1	ko:K00441	ko00680,ko01100,ko01120,map00680,map01100,map01120	-	R03025	RC02628	ko00000,ko00001,ko01000	-	-	-	Fer4,Fer4_10,FrhB_FdhB_C,FrhB_FdhB_N
k59_81473_1	706587.Desti_4160	2.4e-29	110.0	COG0745@1|root,COG0745@2|Bacteria,1MZPD@1224|Proteobacteria,42U2Y@68525|delta/epsilon subdivisions,2WQ1I@28221|Deltaproteobacteria,2MRWP@213462|Syntrophobacterales	28221|Deltaproteobacteria	KT	Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Usp
k59_20335_1	1304885.AUEY01000057_gene682	5.58e-70	230.0	COG1807@1|root,COG1807@2|Bacteria,1P6JE@1224|Proteobacteria,42QEZ@68525|delta/epsilon subdivisions,2WKYB@28221|Deltaproteobacteria,2MJ4D@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
k59_118727_1	1510531.JQJJ01000010_gene2134	9.4e-52	179.0	COG0747@1|root,COG0747@2|Bacteria,1MUZH@1224|Proteobacteria,2TU1J@28211|Alphaproteobacteria,3JRIJ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
k59_210473_1	439235.Dalk_1713	2.77e-46	157.0	29DP0@1|root,300KT@2|Bacteria,1RDQM@1224|Proteobacteria,42S25@68525|delta/epsilon subdivisions,2WNNJ@28221|Deltaproteobacteria,2MJZ0@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF3786)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3786
k59_233376_1	272557.APE_1045.1	1.12e-18	88.6	COG0281@1|root,arCOG01331@2157|Archaea,2XPXF@28889|Crenarchaeota	28889|Crenarchaeota	O	Belongs to the peptidase M48B family	htpX	-	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	Peptidase_M48
k59_224981_1	335543.Sfum_3313	9.07e-68	216.0	COG0583@1|root,COG0583@2|Bacteria,1MWVU@1224|Proteobacteria,42PMQ@68525|delta/epsilon subdivisions,2WKB8@28221|Deltaproteobacteria,2MQEZ@213462|Syntrophobacterales	28221|Deltaproteobacteria	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
k59_28099_1	96561.Dole_0534	0.000993	42.7	COG1215@1|root,COG1215@2|Bacteria,1QU2F@1224|Proteobacteria,42P7H@68525|delta/epsilon subdivisions,2WKJA@28221|Deltaproteobacteria,2MKSR@213118|Desulfobacterales	28221|Deltaproteobacteria	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2,GtrA
k59_172705_1	555779.Dthio_PD2875	2.86e-81	254.0	COG1228@1|root,COG1228@2|Bacteria,1MXXR@1224|Proteobacteria,42ND4@68525|delta/epsilon subdivisions,2WKQP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,Amidohydro_3
k59_104637_1	1356854.N007_12820	3.49e-18	82.8	COG0667@1|root,COG0667@2|Bacteria,1TPIY@1239|Firmicutes,4HA4Q@91061|Bacilli,278WZ@186823|Alicyclobacillaceae	91061|Bacilli	C	aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
k59_119271_1	641491.DND132_2600	9.63e-30	115.0	COG0607@1|root,COG2897@1|root,COG0607@2|Bacteria,COG2897@2|Bacteria,1MU3V@1224|Proteobacteria,42NRF@68525|delta/epsilon subdivisions,2WJZ6@28221|Deltaproteobacteria,2M8PV@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	PFAM Rhodanese domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
k59_83347_1	1232410.KI421421_gene3792	6.64e-101	300.0	COG4420@1|root,COG4420@2|Bacteria,1RIDY@1224|Proteobacteria,42WI7@68525|delta/epsilon subdivisions,2WSAF@28221|Deltaproteobacteria,43VM2@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF1003)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1003
k59_44778_1	1121035.AUCH01000007_gene434	7.19e-21	87.0	2ED9V@1|root,33769@2|Bacteria,1N87Z@1224|Proteobacteria,2W3PP@28216|Betaproteobacteria,2KZ35@206389|Rhodocyclales	206389|Rhodocyclales	S	Protein of unknown function (DUF4242)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4242
k59_44778_3	1121405.dsmv_3008	3.6e-18	80.1	arCOG09439@1|root,32UMB@2|Bacteria,1N1IH@1224|Proteobacteria,42TME@68525|delta/epsilon subdivisions,2WQMU@28221|Deltaproteobacteria,2MKRZ@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_150850_1	243090.RB2200	1.03e-36	140.0	COG0668@1|root,COG0668@2|Bacteria,2J2C2@203682|Planctomycetes	203682|Planctomycetes	M	Mechanosensitive ion channel	-	-	-	ko:K03442,ko:K22044	-	-	-	-	ko00000,ko02000	1.A.23.2,1.A.23.3	-	-	MS_channel
k59_90895_1	335543.Sfum_0413	2.34e-35	137.0	COG0457@1|root,COG1944@1|root,COG0457@2|Bacteria,COG1944@2|Bacteria,1MV7K@1224|Proteobacteria,42N4B@68525|delta/epsilon subdivisions,2WJ34@28221|Deltaproteobacteria,2MRDN@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	YcaO cyclodehydratase, ATP-ad Mg2+-binding	-	-	-	ko:K09136	-	-	-	-	ko00000,ko03009	-	-	-	TPR_1,TPR_16,TPR_2,TPR_8,YcaO
k59_150852_1	1123371.ATXH01000031_gene2163	5.6e-16	75.1	COG0396@1|root,COG0396@2|Bacteria,2GHCR@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	O	ABC transporter	-	-	-	ko:K09013	-	-	-	-	ko00000,ko02000	-	-	-	ABC_tran
k59_37846_1	1047013.AQSP01000098_gene2559	5.15e-52	179.0	COG0481@1|root,COG0481@2|Bacteria,2NNXG@2323|unclassified Bacteria	2|Bacteria	M	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,EFG_II,GTP_EFTU,GTP_EFTU_D2,LepA_C
k59_90901_1	219305.MCAG_00683	9.53e-06	46.6	COG2120@1|root,COG2120@2|Bacteria,2GIUS@201174|Actinobacteria,4DAVI@85008|Micromonosporales	201174|Actinobacteria	S	GlcNAc-PI de-N-acetylase	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
k59_90901_2	1232437.KL661973_gene5019	2.82e-38	137.0	COG0494@1|root,COG0494@2|Bacteria,1NTFG@1224|Proteobacteria,42U22@68525|delta/epsilon subdivisions,2WR0D@28221|Deltaproteobacteria,2MNWH@213118|Desulfobacterales	28221|Deltaproteobacteria	L	NUDIX hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_6333_1	1121439.dsat_0335	3.24e-74	244.0	COG0243@1|root,COG0243@2|Bacteria,1P01N@1224|Proteobacteria,42M9D@68525|delta/epsilon subdivisions,2WJ43@28221|Deltaproteobacteria,2M8UY@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	1.8.5.5	ko:K08352	ko00920,ko01120,map00920,map01120	-	R10149	RC02823	ko00000,ko00001,ko01000,ko02000	5.A.3.5	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
k59_241929_1	335543.Sfum_1225	1.57e-257	743.0	COG0587@1|root,COG0587@2|Bacteria,1MUIF@1224|Proteobacteria,42MGP@68525|delta/epsilon subdivisions,2WIZ2@28221|Deltaproteobacteria,2MQUW@213462|Syntrophobacterales	28221|Deltaproteobacteria	L	DNA polymerase III alpha subunit	dnaE	-	2.7.7.7	ko:K02337,ko:K14162	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
k59_121117_1	1121937.AUHJ01000050_gene1244	4.46e-225	629.0	COG3328@1|root,COG3328@2|Bacteria,1MU4P@1224|Proteobacteria,1RNB3@1236|Gammaproteobacteria,464M3@72275|Alteromonadaceae	1236|Gammaproteobacteria	L	Transposase, Mutator family	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_mut
k59_181200_1	1121396.KB893077_gene738	4e-245	694.0	COG0438@1|root,COG0438@2|Bacteria,1R3Q9@1224|Proteobacteria,42MQ2@68525|delta/epsilon subdivisions,2WM1F@28221|Deltaproteobacteria,2MQ1W@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Glycosyl transferases group 1	-	-	2.4.1.345	ko:K08256	-	-	R11702	-	ko00000,ko01000,ko01003	-	GT4	-	Glyco_transf_4,Glycos_transf_1
k59_181685_1	1245469.S58_44200	3.49e-23	99.4	COG4608@1|root,COG4608@2|Bacteria,1NU4K@1224|Proteobacteria,2TQTV@28211|Alphaproteobacteria,3JVVP@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	P	Oligopeptide/dipeptide transporter, C-terminal region	-	-	-	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
k59_196886_1	1121405.dsmv_2759	1.14e-86	262.0	COG0681@1|root,COG0681@2|Bacteria,1MXUF@1224|Proteobacteria,42NJE@68525|delta/epsilon subdivisions,2WKMA@28221|Deltaproteobacteria,2MIAI@213118|Desulfobacterales	28221|Deltaproteobacteria	U	Belongs to the peptidase S26 family	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
k59_30241_1	335543.Sfum_0676	9.02e-72	229.0	COG0439@1|root,COG0439@2|Bacteria,1MU4H@1224|Proteobacteria,42M14@68525|delta/epsilon subdivisions,2WIN7@28221|Deltaproteobacteria,2MQWN@213462|Syntrophobacterales	28221|Deltaproteobacteria	F	Biotin carboxylase C-terminal domain	accC	-	6.3.4.14,6.4.1.1,6.4.1.2	ko:K01959,ko:K01961	ko00020,ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko01230,map00020,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212,map01230	M00082,M00173,M00376,M00620	R00344,R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
k59_196893_1	1121396.KB893077_gene745	8.94e-64	213.0	COG1075@1|root,COG1075@2|Bacteria,1R5PF@1224|Proteobacteria,43BHB@68525|delta/epsilon subdivisions,2X6VQ@28221|Deltaproteobacteria,2MMMX@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Alpha/beta hydrolase of unknown function (DUF915)	-	-	-	-	-	-	-	-	-	-	-	-	DUF915
k59_166575_1	555779.Dthio_PD1800	2.57e-107	326.0	COG3581@1|root,COG3581@2|Bacteria,1N1N8@1224|Proteobacteria,42UB7@68525|delta/epsilon subdivisions,2WQ9V@28221|Deltaproteobacteria,2MHJM@213115|Desulfovibrionales	28221|Deltaproteobacteria	I	4 iron, 4 sulfur cluster binding	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_181705_1	642492.Clole_2338	1.02e-13	71.2	COG0275@1|root,COG0275@2|Bacteria,1TNZV@1239|Firmicutes,248B5@186801|Clostridia	186801|Clostridia	J	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH	-	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
k59_181705_2	177437.HRM2_12620	4.12e-63	197.0	COG2001@1|root,COG2001@2|Bacteria,1RHCG@1224|Proteobacteria,42TRZ@68525|delta/epsilon subdivisions,2WQRI@28221|Deltaproteobacteria,2MKIW@213118|Desulfobacterales	28221|Deltaproteobacteria	K	Belongs to the MraZ family	mraZ	GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141	-	ko:K03925	-	-	-	-	ko00000	-	-	-	MraZ
k59_196908_1	370438.PTH_2867	1.15e-173	499.0	COG0008@1|root,COG0008@2|Bacteria,1TP8G@1239|Firmicutes,247Y0@186801|Clostridia,2607A@186807|Peptococcaceae	186801|Clostridia	J	PFAM tRNA synthetases class I (E and Q), catalytic domain	glnS	-	6.1.1.18	ko:K01886	ko00970,ko01100,map00970,map01100	M00359,M00360	R03652	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1c,tRNA-synt_1c_C
k59_196908_2	1054213.HMPREF9946_05332	2.83e-29	116.0	COG0556@1|root,COG0556@2|Bacteria,1MUFK@1224|Proteobacteria,2TQSP@28211|Alphaproteobacteria,2JPXK@204441|Rhodospirillales	204441|Rhodospirillales	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
k59_196923_2	1408424.JHYI01000014_gene1269	2.19e-15	79.7	COG5001@1|root,COG5001@2|Bacteria,1TP8V@1239|Firmicutes,4HA3G@91061|Bacilli,1ZAVY@1386|Bacillus	91061|Bacilli	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF,GAF_2,GGDEF,PAS,PAS_4,PAS_9
k59_181720_1	1357279.N018_02785	2.58e-51	179.0	COG3299@1|root,COG3299@2|Bacteria,1PYEJ@1224|Proteobacteria,1S5FS@1236|Gammaproteobacteria,1Z800@136849|Pseudomonas syringae group	1236|Gammaproteobacteria	S	Baseplate J-like protein	jayE	-	-	-	-	-	-	-	-	-	-	-	Baseplate_J
k59_6903_1	706587.Desti_3053	1.06e-108	339.0	COG0653@1|root,COG0653@2|Bacteria,1MUJZ@1224|Proteobacteria,42MMV@68525|delta/epsilon subdivisions,2WIZ4@28221|Deltaproteobacteria,2MQB9@213462|Syntrophobacterales	28221|Deltaproteobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	Helicase_C,SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
k59_151575_1	626887.J057_13006	1.32e-72	226.0	COG0053@1|root,COG0053@2|Bacteria,1MVH8@1224|Proteobacteria,1RQ3E@1236|Gammaproteobacteria,46BQ5@72275|Alteromonadaceae	1236|Gammaproteobacteria	U	Cation efflux family	catA	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
k59_45390_1	1123252.ATZF01000002_gene2616	5.8e-49	171.0	COG0618@1|root,COG0618@2|Bacteria,1TPXX@1239|Firmicutes,4H9ZW@91061|Bacilli,27BHU@186824|Thermoactinomycetaceae	91061|Bacilli	S	DHH family	nrnA	-	3.1.13.3,3.1.3.7	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
k59_242520_1	929556.Solca_0050	1.35e-42	160.0	COG1470@1|root,COG3209@1|root,COG4932@1|root,COG1470@2|Bacteria,COG3209@2|Bacteria,COG4932@2|Bacteria,4PKBQ@976|Bacteroidetes,1J0N1@117747|Sphingobacteriia	976|Bacteroidetes	M	conserved repeat domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Calx-beta,DUF11,SprB
k59_6924_1	338966.Ppro_0827	6.59e-32	120.0	COG0741@1|root,COG0741@2|Bacteria,1MZ4X@1224|Proteobacteria,42TVX@68525|delta/epsilon subdivisions,2WP4F@28221|Deltaproteobacteria,43TTA@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	PFAM Lytic transglycosylase catalytic	-	-	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	DUF4124,SLT
k59_6924_2	1121403.AUCV01000004_gene1930	2.29e-12	64.7	COG0176@1|root,COG0176@2|Bacteria,1MWQ8@1224|Proteobacteria,42M39@68525|delta/epsilon subdivisions,2WJEZ@28221|Deltaproteobacteria,2MI50@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	tal	-	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
k59_151609_1	1121403.AUCV01000024_gene3453	1.43e-16	79.7	COG4967@1|root,COG4967@2|Bacteria,1NI49@1224|Proteobacteria	1224|Proteobacteria	NU	type IV pilus modification protein PilV	pilV	-	-	ko:K02671	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	N_methyl
k59_45409_1	1121405.dsmv_0639	6.6e-61	204.0	COG1164@1|root,COG1164@2|Bacteria	2|Bacteria	E	metalloendopeptidase activity	-	-	-	ko:K08602	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	-
k59_181761_2	321332.CYB_0517	3.87e-09	61.2	COG1462@1|root,COG1462@2|Bacteria,1G2XT@1117|Cyanobacteria,1GYVE@1129|Synechococcus	1117|Cyanobacteria	M	Curli production assembly/transport component CsgG	-	-	-	-	-	-	-	-	-	-	-	-	CsgG
k59_45413_1	1249627.D779_0271	5.44e-56	198.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1WVV9@135613|Chromatiales	135613|Chromatiales	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_3,PAS_4,PAS_9,Response_reg,SBP_bac_3
k59_68191_1	1167006.UWK_01447	1.66e-22	100.0	COG3221@1|root,COG3221@2|Bacteria,1QVNP@1224|Proteobacteria	1224|Proteobacteria	P	ABC transporter, phosphonate, periplasmic substrate-binding protein	-	-	2.7.13.3	ko:K13040	ko02020,map02020	M00514	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	GerE,Phosphonate-bd
k59_6980_1	485916.Dtox_3785	4.29e-110	326.0	COG1352@1|root,COG1352@2|Bacteria,1TRTF@1239|Firmicutes,24D04@186801|Clostridia,261HW@186807|Peptococcaceae	186801|Clostridia	NT	PFAM CheR methyltransferase, SAM binding domain	-	-	2.1.1.80	ko:K00575	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheR,CheR_N
k59_166686_1	871963.Desdi_2207	1.47e-19	87.0	COG0837@1|root,COG0837@2|Bacteria,1VT6V@1239|Firmicutes,24YCM@186801|Clostridia,264CG@186807|Peptococcaceae	186801|Clostridia	F	Belongs to the bacterial glucokinase family	glk	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Glucokinase
k59_45483_2	1232437.KL662072_gene1780	4.49e-44	152.0	COG0043@1|root,COG0043@2|Bacteria,1MU62@1224|Proteobacteria,42MGF@68525|delta/epsilon subdivisions,2WJMB@28221|Deltaproteobacteria,2MIRI@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Belongs to the UbiD family	-	-	4.1.1.98	ko:K03182	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04985,R04986	RC00391	ko00000,ko00001,ko00002,ko01000	-	-	-	UbiD
k59_181822_1	118168.MC7420_5670	4.45e-135	397.0	COG3875@1|root,COG3875@2|Bacteria,1G82E@1117|Cyanobacteria,1HDBH@1150|Oscillatoriales	1117|Cyanobacteria	S	Domain of unknown function (DUF2088)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2088
k59_197073_1	342113.DM82_5347	2.35e-13	72.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,2VGZ8@28216|Betaproteobacteria,1JZWE@119060|Burkholderiaceae	28216|Betaproteobacteria	NT	Cache type 2 domain protein	-	-	-	ko:K03406,ko:K03776,ko:K05874,ko:K05875	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal,TarH,dCache_2,sCache_2
k59_7059_1	1304885.AUEY01000032_gene1991	1.56e-30	123.0	COG1578@1|root,COG1578@2|Bacteria,1R50K@1224|Proteobacteria,42Q0S@68525|delta/epsilon subdivisions,2WJ5M@28221|Deltaproteobacteria,2MIQ5@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Protein of unknown function DUF89	-	-	-	-	-	-	-	-	-	-	-	-	DUF89
k59_166751_1	1343739.PAP_06090	3.73e-11	69.7	COG1530@1|root,arCOG04307@2157|Archaea,2XUGB@28890|Euryarchaeota,243F3@183968|Thermococci	183968|Thermococci	J	Binds to RNA in loop regions with AU-rich sequences	aubA	GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360	-	ko:K22469	-	-	-	-	ko00000,ko03009	-	-	-	DUF402,RNase_E_G
k59_7064_1	1071073.KI530534_gene719	6.65e-08	56.6	COG0745@1|root,COG0745@2|Bacteria,1TSWT@1239|Firmicutes,4HBSC@91061|Bacilli,1ZCSV@1386|Bacillus	91061|Bacilli	T	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	mprA3	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
k59_7064_2	1232437.KL661961_gene3035	6.97e-90	283.0	COG0730@1|root,COG0730@2|Bacteria,1N1I6@1224|Proteobacteria,42N92@68525|delta/epsilon subdivisions,2WJT2@28221|Deltaproteobacteria,2MIX7@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Sulfite exporter TauE/SafE	-	-	-	-	-	-	-	-	-	-	-	-	TauE
k59_7085_1	177437.HRM2_38700	1.66e-74	241.0	COG2414@1|root,COG2414@2|Bacteria,1MWBB@1224|Proteobacteria,42NR7@68525|delta/epsilon subdivisions,2WK49@28221|Deltaproteobacteria,2MHYC@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Aldehyde ferredoxin oxidoreductase	-	-	1.2.7.5	ko:K03738	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00309	R08571	RC00242	ko00000,ko00001,ko00002,ko01000	-	-	-	AFOR_C,AFOR_N
k59_181931_1	981336.F944_00314	2.2e-22	93.6	COG1778@1|root,COG1778@2|Bacteria,1RH85@1224|Proteobacteria,1S6D0@1236|Gammaproteobacteria,3NJB4@468|Moraxellaceae	1236|Gammaproteobacteria	S	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate	kdsC	GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008781,GO:0009058,GO:0009059,GO:0009103,GO:0009987,GO:0016051,GO:0016311,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016791,GO:0019143,GO:0033692,GO:0034637,GO:0034645,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0070567,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509	3.1.3.45	ko:K03270	ko00540,ko01100,map00540,map01100	M00063	R03350	RC00017	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	iECO26_1355.ECO26_4302	Hydrolase_3
k59_181931_2	96561.Dole_0511	8.65e-23	94.7	COG2877@1|root,COG2877@2|Bacteria,1MV91@1224|Proteobacteria,42M61@68525|delta/epsilon subdivisions,2WIXU@28221|Deltaproteobacteria,2MHNJ@213118|Desulfobacterales	28221|Deltaproteobacteria	M	3-deoxy-D-manno-octulosonic acid 8-phosphate synthase	kdsA	-	2.5.1.55	ko:K01627	ko00540,ko01100,map00540,map01100	M00063	R03254	RC00435	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	DAHP_synth_1
k59_7133_1	1123288.SOV_4c07310	7.82e-30	120.0	COG2223@1|root,COG2223@2|Bacteria,1TPTN@1239|Firmicutes,4H9IE@909932|Negativicutes	909932|Negativicutes	P	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
k59_7163_1	1265505.ATUG01000002_gene1896	6.09e-45	160.0	COG2308@1|root,COG2308@2|Bacteria,1NG4H@1224|Proteobacteria,42WK0@68525|delta/epsilon subdivisions,2WS0X@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Evidence 4 Homologs of previously reported genes of	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_7286_1	880072.Desac_0008	7.05e-18	79.3	COG0071@1|root,COG0071@2|Bacteria,1N7C7@1224|Proteobacteria,42U0T@68525|delta/epsilon subdivisions,2WQ7I@28221|Deltaproteobacteria,2MS9G@213462|Syntrophobacterales	28221|Deltaproteobacteria	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
k59_7326_1	9361.ENSDNOP00000027743	0.000516	47.8	COG0457@1|root,KOG1124@2759|Eukaryota,38DM6@33154|Opisthokonta,3BEU3@33208|Metazoa,3CW6P@33213|Bilateria,485D1@7711|Chordata,48XAY@7742|Vertebrata,3J72H@40674|Mammalia	33208|Metazoa	O	tetratricopeptide repeat	TTC6	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_2,TPR_8
k59_7328_1	177437.HRM2_06560	9.92e-48	157.0	2DMB9@1|root,32G5X@2|Bacteria,1RK8Z@1224|Proteobacteria,42TZI@68525|delta/epsilon subdivisions,2WR6A@28221|Deltaproteobacteria,2MKEN@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_7346_1	439235.Dalk_2563	4.68e-103	310.0	COG3303@1|root,COG3303@2|Bacteria,1P8CP@1224|Proteobacteria,42MXS@68525|delta/epsilon subdivisions,2WKEK@28221|Deltaproteobacteria,2MI5R@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Seven times multi-haem cytochrome CxxCH	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554,Multi-haem_cyto
k59_7360_1	215803.DB30_0646	6.41e-164	503.0	COG0085@1|root,COG0085@2|Bacteria,1MUC4@1224|Proteobacteria,43DMZ@68525|delta/epsilon subdivisions,2WIW5@28221|Deltaproteobacteria,2YUEA@29|Myxococcales	28221|Deltaproteobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
k59_7367_1	1267535.KB906767_gene1733	2.31e-08	57.0	COG0016@1|root,COG0016@2|Bacteria,3Y3NJ@57723|Acidobacteria,2JIN8@204432|Acidobacteriia	204432|Acidobacteriia	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily	pheS	-	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Phe_tRNA-synt_N,tRNA-synt_2d
k59_7367_2	1150469.RSPPHO_02019	6.41e-32	114.0	COG0292@1|root,COG0292@2|Bacteria,1RGU2@1224|Proteobacteria,2U756@28211|Alphaproteobacteria,2JSNZ@204441|Rhodospirillales	204441|Rhodospirillales	J	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit	rplT	-	-	ko:K02887	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L20
k59_7393_1	1122947.FR7_1423	7.49e-83	261.0	COG2204@1|root,COG2204@2|Bacteria,1VSKG@1239|Firmicutes,4H6XE@909932|Negativicutes	909932|Negativicutes	T	PFAM sigma-54 factor interaction domain-containing protein, response regulator receiver, helix-turn-helix Fis-type	-	-	-	ko:K07714	ko02020,map02020	M00500	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
k59_7406_1	1121405.dsmv_3526	2.3e-115	336.0	COG1126@1|root,COG1126@2|Bacteria,1MU9Q@1224|Proteobacteria,42M0S@68525|delta/epsilon subdivisions,2WITR@28221|Deltaproteobacteria,2MJ8F@213118|Desulfobacterales	28221|Deltaproteobacteria	E	ABC transporter	-	-	3.6.3.21	ko:K02028,ko:K09972	ko02010,map02010	M00232,M00236	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.3,3.A.1.3.17,3.A.1.3.18,3.A.1.3.7,3.A.1.3.8	-	-	ABC_tran
k59_7443_1	1117647.M5M_04610	2.56e-73	229.0	COG0811@1|root,COG0811@2|Bacteria,1NXZ9@1224|Proteobacteria,1S154@1236|Gammaproteobacteria,1J4YC@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	U	COG0811 Biopolymer transport proteins	-	-	-	-	-	-	-	-	-	-	-	-	MotA_ExbB
k59_7498_1	1265505.ATUG01000001_gene4673	2.34e-101	306.0	COG1653@1|root,COG1653@2|Bacteria,1N98V@1224|Proteobacteria,42VDD@68525|delta/epsilon subdivisions,2WRVU@28221|Deltaproteobacteria,2MM5R@213118|Desulfobacterales	28221|Deltaproteobacteria	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K02027,ko:K10117	ko02010,map02010	M00196,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.28	-	-	SBP_bac_1
k59_7584_1	56780.SYN_00640	5.66e-108	326.0	COG0305@1|root,COG0305@2|Bacteria,1MUG9@1224|Proteobacteria,42M7X@68525|delta/epsilon subdivisions,2WJCA@28221|Deltaproteobacteria,2MQ50@213462|Syntrophobacterales	28221|Deltaproteobacteria	L	it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins	dnaB	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
k59_136462_1	228410.NE0331	8.09e-47	159.0	COG2854@1|root,COG2854@2|Bacteria,1N275@1224|Proteobacteria,2WBHZ@28216|Betaproteobacteria,3735V@32003|Nitrosomonadales	28216|Betaproteobacteria	Q	MlaC protein	-	-	-	ko:K07323	ko02010,map02010	M00210	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27.3	-	-	MlaC
k59_227427_1	1121403.AUCV01000013_gene3954	1.11e-80	267.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2WJ8D@28221|Deltaproteobacteria,2MHXW@213118|Desulfobacterales	28221|Deltaproteobacteria	V	AcrB/AcrD/AcrF family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_219853_1	1379281.AVAG01000029_gene21	9.65e-40	140.0	COG1291@1|root,COG1291@2|Bacteria,1MXK3@1224|Proteobacteria,42PR1@68525|delta/epsilon subdivisions,2WIQ8@28221|Deltaproteobacteria,2M7ZH@213115|Desulfovibrionales	28221|Deltaproteobacteria	N	PFAM MotA TolQ ExbB proton channel	motA	-	-	ko:K02556	ko02020,ko02030,ko02040,map02020,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	MotA_ExbB
k59_68240_1	1122244.AUGF01000035_gene1097	2.06e-05	50.1	COG0484@1|root,COG0484@2|Bacteria	2|Bacteria	O	heat shock protein binding	-	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
k59_83396_1	879212.DespoDRAFT_02792	2.26e-70	229.0	COG0018@1|root,COG0018@2|Bacteria,1MU4J@1224|Proteobacteria,42MTY@68525|delta/epsilon subdivisions,2WKII@28221|Deltaproteobacteria,2MI2W@213118|Desulfobacterales	28221|Deltaproteobacteria	J	TIGRFAM arginyl-tRNA synthetase	argS	GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	iAF987.Gmet_1434	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
k59_151628_2	589865.DaAHT2_0407	1.22e-08	55.8	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WKJX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
k59_22759_1	880072.Desac_0544	9.95e-64	217.0	COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1145@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1145@2|Bacteria,1MVM0@1224|Proteobacteria,42MZ0@68525|delta/epsilon subdivisions,2WJ96@28221|Deltaproteobacteria,2MSJC@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	Pyruvate:ferredoxin oxidoreductase core domain II	por	-	1.2.7.1	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00173,M00307	R01196,R10866	RC00004,RC02742	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	EKR,Fer4_16,Fer4_7,PFOR_II,POR,POR_N,TPP_enzyme_C
k59_174382_1	177437.HRM2_44900	1.55e-11	63.5	COG3571@1|root,COG3571@2|Bacteria,1RD20@1224|Proteobacteria,42SGK@68525|delta/epsilon subdivisions,2WPDI@28221|Deltaproteobacteria,2MK9B@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Alpha/beta hydrolase family	-	-	-	ko:K07020	-	-	-	-	ko00000	-	-	-	Abhydrolase_4,Abhydrolase_5,DLH
k59_174382_2	644282.Deba_2408	1.78e-165	490.0	COG0480@1|root,COG0480@2|Bacteria,1MUCV@1224|Proteobacteria,42M4T@68525|delta/epsilon subdivisions,2WIM7@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA-2	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
k59_90986_1	472759.Nhal_1867	2.85e-36	138.0	COG0845@1|root,COG0845@2|Bacteria,1PEVY@1224|Proteobacteria,1RPEQ@1236|Gammaproteobacteria,1WZ1A@135613|Chromatiales	135613|Chromatiales	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3
k59_197136_2	1304872.JAGC01000009_gene486	3.31e-24	104.0	COG0574@1|root,COG3848@1|root,COG0574@2|Bacteria,COG3848@2|Bacteria,1QFX3@1224|Proteobacteria,42PIP@68525|delta/epsilon subdivisions,2WKWI@28221|Deltaproteobacteria,2MG9J@213115|Desulfovibrionales	28221|Deltaproteobacteria	G	PFAM Pyruvate phosphate dikinase, PEP pyruvate-binding	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PPDK_N
k59_60681_1	1121403.AUCV01000018_gene3159	1.08e-74	234.0	COG0115@1|root,COG0115@2|Bacteria,1MVB0@1224|Proteobacteria,42MKX@68525|delta/epsilon subdivisions,2WJ7X@28221|Deltaproteobacteria,2MIWF@213118|Desulfobacterales	28221|Deltaproteobacteria	E	TIGRFAM branched-chain amino acid aminotransferase	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	iAF987.Gmet_2853	Aminotran_4
k59_60682_1	1121405.dsmv_0805	1.76e-116	344.0	COG0722@1|root,COG0722@2|Bacteria,1MU5Q@1224|Proteobacteria,42PQY@68525|delta/epsilon subdivisions,2WJXE@28221|Deltaproteobacteria,2MIIR@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)	-	-	2.5.1.54	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_1
k59_4127_1	1121448.DGI_1873	4.15e-32	135.0	COG2204@1|root,COG4191@1|root,COG2204@2|Bacteria,COG4191@2|Bacteria,1QZPK@1224|Proteobacteria,42NQE@68525|delta/epsilon subdivisions,2WJPH@28221|Deltaproteobacteria,2M8MZ@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,PAS_4,PAS_9,Response_reg
k59_202248_2	596152.DesU5LDRAFT_0918	3.2e-26	114.0	COG4191@1|root,COG4191@2|Bacteria,1P0U1@1224|Proteobacteria,42PTP@68525|delta/epsilon subdivisions,2WJ8U@28221|Deltaproteobacteria,2M8NY@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
k59_73368_2	1125863.JAFN01000001_gene2101	6.37e-48	155.0	COG1993@1|root,COG1993@2|Bacteria,1N0EM@1224|Proteobacteria,42TZK@68525|delta/epsilon subdivisions,2WQ2E@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Uncharacterized ACR, COG1993	-	-	-	ko:K09137	-	-	-	-	ko00000	-	-	-	CBS,DUF190
k59_65276_1	1121447.JONL01000002_gene2257	1.72e-42	157.0	COG1026@1|root,COG1026@2|Bacteria,1MVDJ@1224|Proteobacteria,42MRG@68525|delta/epsilon subdivisions,2WJ5Q@28221|Deltaproteobacteria,2M9EM@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	PFAM Peptidase M16C associated	PREP	-	-	ko:K06972	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M16C_assoc,Peptidase_M16,Peptidase_M16_C
k59_50106_1	1121456.ATVA01000018_gene409	5.59e-42	154.0	COG0569@1|root,COG0589@1|root,COG0569@2|Bacteria,COG0589@2|Bacteria,1QZ59@1224|Proteobacteria,43CFV@68525|delta/epsilon subdivisions,2WR2F@28221|Deltaproteobacteria,2M9AU@213115|Desulfovibrionales	28221|Deltaproteobacteria	PT	TrkA-N domain	-	-	-	ko:K03499,ko:K09944	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N,Usp
k59_202254_1	370438.PTH_2737	2.46e-71	240.0	COG0178@1|root,COG0178@2|Bacteria,1TPIJ@1239|Firmicutes,2485F@186801|Clostridia,260NC@186807|Peptococcaceae	186801|Clostridia	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
k59_163833_1	1042375.AFPL01000036_gene3077	6.21e-44	160.0	COG0671@1|root,COG0671@2|Bacteria,1PX74@1224|Proteobacteria,1S52W@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	LssY C-terminus	-	-	-	-	-	-	-	-	-	-	-	-	LssY_C
k59_65281_1	1229909.NSED_02265	2.14e-22	92.4	COG1382@1|root,arCOG01342@2157|Archaea,41SPD@651137|Thaumarchaeota	651137|Thaumarchaeota	O	Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding	pfdB	-	-	ko:K04798	-	-	-	-	ko00000,ko03110	-	-	-	Prefoldin_2
k59_42393_1	1121405.dsmv_2597	2.4e-129	391.0	COG1674@1|root,COG1674@2|Bacteria,1MVPI@1224|Proteobacteria,42N4X@68525|delta/epsilon subdivisions,2WIPR@28221|Deltaproteobacteria,2MI69@213118|Desulfobacterales	28221|Deltaproteobacteria	D	DNA segregation ATPase, FtsK SpoIIIE family	ftsK	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
k59_126621_1	706587.Desti_5385	1.61e-116	358.0	COG2204@1|root,COG3850@1|root,COG2204@2|Bacteria,COG3850@2|Bacteria,1MU0N@1224|Proteobacteria,43BK2@68525|delta/epsilon subdivisions,2X6XX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Sigma-54 factor interaction domain-containing protein	-	-	-	ko:K02481,ko:K07712,ko:K07713	ko02020,map02020	M00497,M00499	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,PAS_4,Response_reg,Sigma54_activat
k59_80979_1	335543.Sfum_0294	6.59e-47	171.0	COG0591@1|root,COG1842@1|root,COG3852@1|root,COG0591@2|Bacteria,COG1842@2|Bacteria,COG3852@2|Bacteria,1NTTH@1224|Proteobacteria,43CEX@68525|delta/epsilon subdivisions,2X7PW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	SMART PAS domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	HisKA,PAS
k59_103658_1	1382315.JPOI01000001_gene3036	2.81e-65	214.0	COG0452@1|root,COG0452@2|Bacteria,1TPP3@1239|Firmicutes,4HAK8@91061|Bacilli,1WFSN@129337|Geobacillus	91061|Bacilli	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	coaBC	-	4.1.1.36,6.3.2.5	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
k59_35543_1	497964.CfE428DRAFT_2340	7.89e-41	151.0	COG0012@1|root,COG0012@2|Bacteria,46UY8@74201|Verrucomicrobia	74201|Verrucomicrobia	J	GTP binding	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_88222_1	439235.Dalk_1046	3.49e-75	249.0	COG1132@1|root,COG1132@2|Bacteria,1MWTY@1224|Proteobacteria,42N23@68525|delta/epsilon subdivisions,2WKW2@28221|Deltaproteobacteria,2MHZB@213118|Desulfobacterales	28221|Deltaproteobacteria	V	ABC transporter transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	ABC_membrane,ABC_tran
k59_187363_1	556269.ACDQ01000017_gene858	1.62e-36	145.0	COG2199@1|root,COG3287@1|root,COG2199@2|Bacteria,COG3287@2|Bacteria,1R4QY@1224|Proteobacteria,2WGUB@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
k59_35549_1	335543.Sfum_1937	6.66e-77	249.0	COG1009@1|root,COG1009@2|Bacteria,1MW2M@1224|Proteobacteria,42KZE@68525|delta/epsilon subdivisions,2WIPT@28221|Deltaproteobacteria,2MR8Q@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	NADH-Ubiquinone oxidoreductase (complex I), chain 5	nuoL-2	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_C,Proton_antipo_M,Proton_antipo_N
k59_194009_1	933262.AXAM01000048_gene2589	3.71e-70	224.0	COG0743@1|root,COG0743@2|Bacteria,1MU4G@1224|Proteobacteria,42NI1@68525|delta/epsilon subdivisions,2WK14@28221|Deltaproteobacteria,2MIFC@213118|Desulfobacterales	28221|Deltaproteobacteria	I	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)	dxr	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576	1.1.1.267	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05688	RC01452	ko00000,ko00001,ko00002,ko01000	-	-	-	DXPR_C,DXP_redisom_C,DXP_reductoisom
k59_95996_1	879212.DespoDRAFT_02330	2.79e-60	204.0	COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,42M01@68525|delta/epsilon subdivisions,2WJ7M@28221|Deltaproteobacteria,2MHMW@213118|Desulfobacterales	28221|Deltaproteobacteria	V	Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation	msbA	-	-	ko:K06147,ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
k59_163862_2	1479237.JMLY01000001_gene827	1.47e-27	116.0	COG0697@1|root,COG2199@1|root,COG0697@2|Bacteria,COG3706@2|Bacteria,1NECV@1224|Proteobacteria,1S1ZR@1236|Gammaproteobacteria,46766@72275|Alteromonadaceae	1236|Gammaproteobacteria	T	COG2199 FOG GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,GAF_2,GGDEF
k59_88235_1	335543.Sfum_0552	5.01e-32	124.0	COG0477@1|root,COG2814@2|Bacteria,1MVSH@1224|Proteobacteria,42NA4@68525|delta/epsilon subdivisions,2WKTU@28221|Deltaproteobacteria,2MQRV@213462|Syntrophobacterales	28221|Deltaproteobacteria	EGP	PFAM Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
k59_19894_2	1121918.ARWE01000001_gene2221	2.09e-37	130.0	COG0589@1|root,COG0589@2|Bacteria,1Q0M5@1224|Proteobacteria,430YY@68525|delta/epsilon subdivisions,2WVQA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
k59_103675_1	502025.Hoch_6580	1.4e-11	65.1	COG1309@1|root,COG1309@2|Bacteria,1RCDH@1224|Proteobacteria,42VJ5@68525|delta/epsilon subdivisions,2WXCH@28221|Deltaproteobacteria,2Z381@29|Myxococcales	28221|Deltaproteobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	ko:K13770	-	-	-	-	ko00000,ko03000	-	-	-	TetR_N
k59_96002_1	1283300.ATXB01000001_gene1128	7.8e-20	90.1	COG4623@1|root,COG4623@2|Bacteria,1MWDS@1224|Proteobacteria,1RM8W@1236|Gammaproteobacteria,1XF9A@135618|Methylococcales	135618|Methylococcales	M	Transglycosylase SLT domain	-	-	-	ko:K18691	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	SBP_bac_3,SLT
k59_20342_1	42254.XP_004607296.1	1.9e-05	49.3	COG1057@1|root,KOG3199@2759|Eukaryota,38BZ1@33154|Opisthokonta,3BJ10@33208|Metazoa,3CSJ4@33213|Bilateria,482G0@7711|Chordata,495G7@7742|Vertebrata,3JAHH@40674|Mammalia	33208|Metazoa	H	adenylyltransferase 1	NMNAT1	GO:0000309,GO:0001894,GO:0001895,GO:0003674,GO:0003824,GO:0004515,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0006082,GO:0006139,GO:0006163,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009435,GO:0009611,GO:0009987,GO:0016043,GO:0016604,GO:0016740,GO:0016772,GO:0016779,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019693,GO:0019752,GO:0030030,GO:0031974,GO:0031981,GO:0032501,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0036477,GO:0042592,GO:0042802,GO:0043025,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043648,GO:0043954,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044297,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044451,GO:0044464,GO:0045494,GO:0046034,GO:0046483,GO:0046496,GO:0048871,GO:0050808,GO:0050896,GO:0051082,GO:0051186,GO:0051188,GO:0055086,GO:0060249,GO:0065007,GO:0065008,GO:0070013,GO:0070566,GO:0071704,GO:0071840,GO:0072521,GO:0072524,GO:0072525,GO:0090407,GO:0097061,GO:0097062,GO:0097458,GO:0099173,GO:0106027,GO:0120036,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1990966	2.7.7.1,2.7.7.18	ko:K06210	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
k59_20342_2	1357399.HMPREF2087_00802	1.51e-15	76.6	COG1215@1|root,COG1215@2|Bacteria,1QU2F@1224|Proteobacteria,42P7H@68525|delta/epsilon subdivisions	1224|Proteobacteria	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2,GtrA,Methyltransf_23,Methyltransf_31
k59_194430_2	1125863.JAFN01000001_gene613	8.68e-36	134.0	COG0677@1|root,COG0677@2|Bacteria,1MUC6@1224|Proteobacteria,42M4F@68525|delta/epsilon subdivisions,2WKK3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM UDP-glucose GDP-mannose dehydrogenase	-	-	1.1.1.136	ko:K02474,ko:K13015	ko00520,map00520	-	R00421,R06894	RC00291	ko00000,ko00001,ko01000,ko01005	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
k59_148954_1	1565129.JSFF01000014_gene434	5.67e-12	71.6	COG1361@1|root,COG1361@2|Bacteria,1R6R8@1224|Proteobacteria,1RZFS@1236|Gammaproteobacteria,2Q9ZJ@267890|Shewanellaceae	1236|Gammaproteobacteria	M	Conserved repeat domain	-	-	-	-	-	-	-	-	-	-	-	-	NPCBM_assoc
k59_127029_1	292459.STH24	3.46e-17	85.9	COG4585@1|root,COG4585@2|Bacteria,1TQI3@1239|Firmicutes,249R9@186801|Clostridia	186801|Clostridia	T	Histidine kinase	-	-	2.7.13.3	ko:K07777	ko02020,map02020	M00478	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA_3,PAS
k59_217614_1	933262.AXAM01000027_gene2113	1.1e-35	135.0	COG1716@1|root,COG2304@1|root,COG1716@2|Bacteria,COG2304@2|Bacteria	2|Bacteria	IU	oxidoreductase activity	-	-	-	ko:K08777	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	FHA,VWA
k59_73801_1	316067.Geob_0397	7.53e-101	313.0	COG2766@1|root,COG2766@2|Bacteria,1PXNG@1224|Proteobacteria,42N5G@68525|delta/epsilon subdivisions,2WINM@28221|Deltaproteobacteria,43S13@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	PrkA AAA domain	prkA	-	-	ko:K07180	-	-	-	-	ko00000	-	-	-	AAA_PrkA,PrkA
k59_157226_1	933262.AXAM01000085_gene1063	8.49e-128	369.0	COG0805@1|root,COG0805@2|Bacteria,1MVAY@1224|Proteobacteria,42MM7@68525|delta/epsilon subdivisions,2WKJW@28221|Deltaproteobacteria,2MI7G@213118|Desulfobacterales	28221|Deltaproteobacteria	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides	tatC	-	-	ko:K03118	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	TatC
k59_179362_1	335543.Sfum_0313	1.41e-83	255.0	COG0559@1|root,COG0559@2|Bacteria,1N5XH@1224|Proteobacteria,42PN7@68525|delta/epsilon subdivisions,2WIRP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
k59_210495_1	644282.Deba_1961	6.23e-30	120.0	COG1508@1|root,COG1508@2|Bacteria,1MW4V@1224|Proteobacteria,42M3C@68525|delta/epsilon subdivisions,2WJ21@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	rpoN	-	-	ko:K03092	ko02020,ko05111,map02020,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma54_AID,Sigma54_CBD,Sigma54_DBD
k59_58944_1	316056.RPC_2387	3.29e-48	156.0	COG0347@1|root,COG0347@2|Bacteria,1RGWK@1224|Proteobacteria,2U73Z@28211|Alphaproteobacteria,3JYUA@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	K	Belongs to the P(II) protein family	glnB	GO:0003674,GO:0006808,GO:0008150,GO:0030234,GO:0050789,GO:0050790,GO:0065007,GO:0065009,GO:0098772	-	ko:K04751	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	P-II
k59_58944_2	1265505.ATUG01000001_gene3204	2.72e-10	60.8	COG0004@1|root,COG0004@2|Bacteria,1NR9F@1224|Proteobacteria,42M8M@68525|delta/epsilon subdivisions,2WJE2@28221|Deltaproteobacteria,2MISS@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Ammonium Transporter	-	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
k59_50578_1	933262.AXAM01000014_gene278	1.15e-51	183.0	COG0642@1|root,COG4251@1|root,COG0642@2|Bacteria,COG4251@2|Bacteria,1NSQ1@1224|Proteobacteria,43CDW@68525|delta/epsilon subdivisions,2X8IN@28221|Deltaproteobacteria,2MPP7@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Histidine kinase-like ATPases	-	-	-	-	-	-	-	-	-	-	-	-	CHASE4,HAMP,HATPase_c,HisKA,Hpt,PAS_9,Response_reg
k59_202812_1	1232410.KI421422_gene2092	4.25e-29	109.0	COG1592@1|root,COG1592@2|Bacteria,1R9WG@1224|Proteobacteria,42RFX@68525|delta/epsilon subdivisions,2WN92@28221|Deltaproteobacteria,43UKR@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Rubrerythrin	-	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
k59_50585_1	1122222.AXWR01000040_gene646	9.94e-12	63.2	COG0824@1|root,COG0824@2|Bacteria,1WNB2@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Thioesterase-like superfamily	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT,4HBT_2
k59_50585_2	485916.Dtox_4179	1.12e-11	65.1	COG0394@1|root,COG0394@2|Bacteria,1VA05@1239|Firmicutes,25CRM@186801|Clostridia,262N5@186807|Peptococcaceae	186801|Clostridia	T	Low molecular weight phosphotyrosine protein phosphatase	ywlE	-	3.1.3.48,3.9.1.2	ko:K01104,ko:K20201	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
k59_127036_1	1246448.ANAZ01000010_gene3244	4.07e-50	172.0	COG1703@1|root,COG1703@2|Bacteria,2GME8@201174|Actinobacteria,4EHVD@85012|Streptosporangiales	201174|Actinobacteria	E	ArgK protein	argK	-	-	ko:K07588	-	-	-	-	ko00000,ko01000	-	-	-	ArgK
k59_127036_2	335543.Sfum_0455	4.88e-72	218.0	COG0346@1|root,COG0346@2|Bacteria,1RCYU@1224|Proteobacteria,42URG@68525|delta/epsilon subdivisions,2WNDG@28221|Deltaproteobacteria,2MRYD@213462|Syntrophobacterales	28221|Deltaproteobacteria	E	PFAM Glyoxalase bleomycin resistance protein dioxygenase	mceE	-	5.1.99.1	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R02765,R09979	RC00780,RC02739	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase_4
k59_127036_3	880072.Desac_2814	8.28e-115	343.0	COG4799@1|root,COG4799@2|Bacteria,1MVAX@1224|Proteobacteria,43AEE@68525|delta/epsilon subdivisions,2WIRF@28221|Deltaproteobacteria,2MQFX@213462|Syntrophobacterales	28221|Deltaproteobacteria	I	Acetyl-CoA carboxylase carboxyltransferase component (subunits alpha and beta)	-	-	2.1.3.1,2.1.3.15,6.4.1.3	ko:K01966,ko:K17489	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	M00373,M00741	R00353,R01859	RC00040,RC00097,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
k59_187955_1	365528.KB891164_gene5217	5.23e-15	77.8	COG0582@1|root,COG0582@2|Bacteria,2I9B8@201174|Actinobacteria	201174|Actinobacteria	L	Integrase	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
k59_65728_1	933262.AXAM01000061_gene1671	9.84e-08	56.6	COG4726@1|root,COG4726@2|Bacteria,1NC4I@1224|Proteobacteria,42VGI@68525|delta/epsilon subdivisions,2WS7G@28221|Deltaproteobacteria,2MM9W@213118|Desulfobacterales	28221|Deltaproteobacteria	NU	PilX N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	PilX_N
k59_240097_1	933262.AXAM01000031_gene3022	1.58e-84	261.0	COG0330@1|root,COG0330@2|Bacteria,1MUM2@1224|Proteobacteria,42NUT@68525|delta/epsilon subdivisions,2WKQX@28221|Deltaproteobacteria,2MI5I@213118|Desulfobacterales	28221|Deltaproteobacteria	O	HflC and HflK could encode or regulate a protease	hflK	-	-	ko:K04088	-	M00742	-	-	ko00000,ko00002,ko01000	-	-	-	Band_7
k59_50599_1	1120985.AUMI01000016_gene1840	2.5e-61	193.0	COG0454@1|root,COG0456@2|Bacteria,1V8UP@1239|Firmicutes,4H4QH@909932|Negativicutes	909932|Negativicutes	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
k59_50599_2	1167006.UWK_00633	2.35e-13	66.2	COG0252@1|root,COG0252@2|Bacteria,1RHAW@1224|Proteobacteria,42SNH@68525|delta/epsilon subdivisions,2WPQC@28221|Deltaproteobacteria,2MK6U@213118|Desulfobacterales	28221|Deltaproteobacteria	EJ	Asparaginase, N-terminal	aspG	-	3.5.1.1	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	-	R00485	RC00010,RC02798	ko00000,ko00001,ko01000	-	-	-	Asparaginase
k59_81496_1	879212.DespoDRAFT_00649	8.56e-41	145.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,42NHU@68525|delta/epsilon subdivisions,2WIZ1@28221|Deltaproteobacteria,2MIQ6@213118|Desulfobacterales	28221|Deltaproteobacteria	I	acyl-CoA dehydrogenase	-	-	1.3.99.32	ko:K16173	ko00362,ko01120,map00362,map01120	-	R05579	RC00052	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
k59_194462_1	1232410.KI421424_gene1653	1.56e-54	184.0	COG3481@1|root,COG3481@2|Bacteria,1NH0C@1224|Proteobacteria,42Q7X@68525|delta/epsilon subdivisions,2WJW2@28221|Deltaproteobacteria,43T29@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	nucleic acid binding OB-fold tRNA helicase-type	yhaM	-	-	ko:K03698	-	-	-	-	ko00000,ko01000,ko03019	-	-	-	HD,tRNA_anti-codon
k59_225005_1	104355.XP_007867883.1	3.55e-08	60.5	COG3236@1|root,2S5B2@2759|Eukaryota,3A7MC@33154|Opisthokonta,3P57U@4751|Fungi,3V5KW@5204|Basidiomycota,22A6K@155619|Agaricomycetes,3H8W5@355688|Agaricomycetes incertae sedis	4751|Fungi	S	Domain of unknown function (DUF1768)	-	-	1.1.1.193,3.5.4.26	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF1768
k59_58951_1	1304885.AUEY01000036_gene2247	1.87e-84	266.0	COG0591@1|root,COG0591@2|Bacteria,1PNHU@1224|Proteobacteria,43AQ2@68525|delta/epsilon subdivisions,2X63U@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Sodium:solute symporter family	-	-	-	-	-	-	-	-	-	-	-	-	SSF
k59_27699_1	439235.Dalk_1926	6.9e-78	236.0	COG0250@1|root,COG0250@2|Bacteria,1MU14@1224|Proteobacteria,42MPQ@68525|delta/epsilon subdivisions,2WMP6@28221|Deltaproteobacteria,2MHS4@213118|Desulfobacterales	28221|Deltaproteobacteria	K	Participates in transcription elongation, termination and antitermination	nusG	-	-	ko:K02601	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KOW,NusG
k59_81499_1	526222.Desal_0829	7.32e-43	150.0	COG0437@1|root,COG0437@2|Bacteria,1QMKB@1224|Proteobacteria,42MPX@68525|delta/epsilon subdivisions,2WIKF@28221|Deltaproteobacteria,2M9F3@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_10,Fer4_11,Fer4_7,TAT_signal
k59_240102_1	349519.LCK_00249	3.81e-27	108.0	COG0357@1|root,COG0357@2|Bacteria,1TPBT@1239|Firmicutes,4HAAZ@91061|Bacilli,4AX58@81850|Leuconostocaceae	91061|Bacilli	J	Specifically methylates the N7 position of a guanine in 16S rRNA	rsmG	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.170	ko:K03501	-	-	-	-	ko00000,ko01000,ko03009,ko03036	-	-	-	GidB
k59_240102_2	1123372.AUIT01000007_gene472	1.98e-14	73.6	COG0486@1|root,COG0486@2|Bacteria,2GHES@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	S	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34	mnmE	-	-	ko:K03650	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko01000,ko03016	-	-	-	MMR_HSR1,MnmE_helical,TrmE_N
k59_50604_1	439235.Dalk_4108	1.86e-105	319.0	COG1215@1|root,COG1215@2|Bacteria,1MWH9@1224|Proteobacteria,42PX0@68525|delta/epsilon subdivisions,2WJUG@28221|Deltaproteobacteria,2MK7E@213118|Desulfobacterales	28221|Deltaproteobacteria	M	COG0463 Glycosyltransferases involved in cell wall biogenesis	-	-	2.4.1.266	ko:K13693	-	-	-	-	ko00000,ko01000,ko01003	-	GT81	-	-
k59_127038_1	1125863.JAFN01000001_gene3268	1.02e-19	96.7	COG2206@1|root,COG2206@2|Bacteria,1RAQS@1224|Proteobacteria,42MEJ@68525|delta/epsilon subdivisions,2WP5V@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	metal-dependent phosphohydrolase, HD sub domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HAMP,HD,HD_5
k59_81502_1	96561.Dole_0767	7.7e-38	146.0	COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,1MUKF@1224|Proteobacteria,42N3S@68525|delta/epsilon subdivisions,2WJ5P@28221|Deltaproteobacteria,2MI3T@213118|Desulfobacterales	28221|Deltaproteobacteria	S	DNA internalization-related competence protein ComEC Rec2	-	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131,Lactamase_B
k59_179385_1	335543.Sfum_2306	2.71e-66	216.0	COG0683@1|root,COG0683@2|Bacteria,1MWJ1@1224|Proteobacteria,42MSJ@68525|delta/epsilon subdivisions,2WMCE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	PFAM Extracellular ligand-binding receptor	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
k59_194474_1	1499967.BAYZ01000134_gene8	1.16e-89	285.0	COG1509@1|root,COG1509@2|Bacteria	2|Bacteria	E	lysine 2,3-aminomutase activity	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_14,Radical_SAM
k59_73834_1	1304888.ATWF01000002_gene492	6.59e-36	135.0	COG1879@1|root,COG1879@2|Bacteria	2|Bacteria	G	ABC-type sugar transport system periplasmic component	-	-	-	ko:K10439	ko02010,ko02030,map02010,map02030	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	Peripla_BP_4
k59_118761_1	370438.PTH_2223	1.71e-120	357.0	COG3287@1|root,COG3287@2|Bacteria,1UK57@1239|Firmicutes,24A5H@186801|Clostridia	186801|Clostridia	S	FIST N domain	-	-	-	-	-	-	-	-	-	-	-	-	FIST,FIST_C
k59_240115_1	335543.Sfum_1549	2.17e-105	337.0	COG0085@1|root,COG0085@2|Bacteria,1MUC4@1224|Proteobacteria,43DMZ@68525|delta/epsilon subdivisions,2WIW5@28221|Deltaproteobacteria,2MR0B@213462|Syntrophobacterales	28221|Deltaproteobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
k59_202837_2	335543.Sfum_1575	6.07e-66	213.0	COG0201@1|root,COG0201@2|Bacteria,1MVU7@1224|Proteobacteria,42MGM@68525|delta/epsilon subdivisions,2WIZ7@28221|Deltaproteobacteria,2MQSV@213462|Syntrophobacterales	28221|Deltaproteobacteria	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	-	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
k59_240117_1	335543.Sfum_2106	2.13e-25	104.0	COG1048@1|root,COG1048@2|Bacteria,1MU9T@1224|Proteobacteria,42N5M@68525|delta/epsilon subdivisions,2WIIV@28221|Deltaproteobacteria,2MRHI@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	aconitate hydratase	-	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2763	Aconitase,Aconitase_C
k59_240117_2	1167006.UWK_00417	1.22e-53	177.0	COG0705@1|root,COG0705@2|Bacteria,1PRTP@1224|Proteobacteria,42M6N@68525|delta/epsilon subdivisions,2WJW4@28221|Deltaproteobacteria,2MJR6@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Rhomboid family	-	-	3.4.21.105	ko:K19225	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Rhomboid
k59_149001_1	1472716.KBK24_0120585	3.92e-41	145.0	COG4455@1|root,COG4455@2|Bacteria,1MWHI@1224|Proteobacteria,2VKHG@28216|Betaproteobacteria,1K3TU@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Virulence protein SciE type	-	-	-	ko:K11898	-	-	-	-	ko00000,ko02044	-	-	-	ImpE
k59_154089_1	7668.SPU_016323-tr	2.59e-32	129.0	KOG1075@1|root,KOG1075@2759|Eukaryota,39Y6T@33154|Opisthokonta,3BEGN@33208|Metazoa,3CZ7K@33213|Bilateria	33208|Metazoa	G	positive regulation of TOR signaling	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos_2,RVT_1
k59_40196_1	511051.CSE_12210	7.07e-08	56.2	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	-	-	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1
k59_115719_1	999425.HMPREF9186_00735	2.2e-55	181.0	COG0410@1|root,COG0410@2|Bacteria,1TPW4@1239|Firmicutes,4HABJ@91061|Bacilli	91061|Bacilli	E	COG0410 ABC-type branched-chain amino acid transport systems, ATPase component	livF	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
k59_115719_2	667014.Thein_0546	5.43e-68	225.0	COG0145@1|root,COG0145@2|Bacteria,2GGWU@200940|Thermodesulfobacteria	2|Bacteria	EQ	PFAM Hydantoinase oxoprolinase	hyuA	-	3.5.2.14,3.5.2.9	ko:K01469,ko:K01473	ko00330,ko00480,ko01100,map00330,map00480,map01100	-	R00251,R03187	RC00553,RC00632	ko00000,ko00001,ko01000	-	-	-	Hydant_A_N,Hydantoinase_A,Hydantoinase_B
k59_78245_1	335543.Sfum_0821	3.7e-299	859.0	COG1148@1|root,COG2204@1|root,COG1148@2|Bacteria,COG2204@2|Bacteria,1QUM4@1224|Proteobacteria,42MPP@68525|delta/epsilon subdivisions,2WJ3U@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	4Fe-4S ferredoxin iron-sulfur binding domain protein	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,FAD_oxidored,Fer4,Fer4_7,NAD_binding_8,Pyr_redox_2,Response_reg
k59_176620_1	608538.HTH_0272	5.18e-32	122.0	COG3408@1|root,COG3408@2|Bacteria,2G59I@200783|Aquificae	200783|Aquificae	G	Glycogen debranching enzyme	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_47782_1	530564.Psta_1290	8.82e-33	119.0	COG4422@1|root,COG4422@2|Bacteria,2IY1I@203682|Planctomycetes	203682|Planctomycetes	S	COG4422 Bacteriophage protein gp37	-	-	-	-	-	-	-	-	-	-	-	-	DUF5131
k59_222223_1	391603.FBALC1_14202	3.61e-68	211.0	COG1028@1|root,COG1028@2|Bacteria,4NGAH@976|Bacteroidetes,1HZ3Z@117743|Flavobacteriia	976|Bacteroidetes	IQ	with different specificities (Related to short-chain alcohol	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
k59_9953_1	1307759.JOMJ01000003_gene1418	8.93e-12	66.2	COG0607@1|root,COG2897@1|root,COG0607@2|Bacteria,COG2897@2|Bacteria,1MU3V@1224|Proteobacteria,42NRF@68525|delta/epsilon subdivisions,2WJZ6@28221|Deltaproteobacteria,2M8PV@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	PFAM Rhodanese domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
k59_9953_2	1121440.AUMA01000011_gene2429	2.06e-24	100.0	COG0607@1|root,COG2897@1|root,COG0607@2|Bacteria,COG2897@2|Bacteria,1MU3V@1224|Proteobacteria,42NRF@68525|delta/epsilon subdivisions,2WJZ6@28221|Deltaproteobacteria,2M8PV@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	PFAM Rhodanese domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
k59_237315_1	404589.Anae109_3810	2.74e-63	201.0	COG1428@1|root,COG1428@2|Bacteria,1RC50@1224|Proteobacteria	1224|Proteobacteria	F	Deoxynucleoside kinase	dgk	-	-	-	-	-	-	-	-	-	-	-	dNK
k59_100888_2	316067.Geob_3650	9.27e-32	125.0	COG2304@1|root,COG2304@2|Bacteria,1MW8K@1224|Proteobacteria,42NNC@68525|delta/epsilon subdivisions,2WKQW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	von Willebrand factor, type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VIT,VWA_3
k59_154110_1	1121422.AUMW01000013_gene1462	2.04e-73	229.0	COG0119@1|root,COG0119@2|Bacteria,1TQG3@1239|Firmicutes,24AUV@186801|Clostridia	186801|Clostridia	E	HMGL-like	mvaB	-	4.1.3.4	ko:K01640	ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146	M00036,M00088	R01360,R08090	RC00502,RC00503,RC01118,RC01946	ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like
k59_115742_1	401526.TcarDRAFT_1842	9.23e-44	161.0	COG3829@1|root,COG3829@2|Bacteria,1TP0E@1239|Firmicutes,4H2QY@909932|Negativicutes	909932|Negativicutes	KT	PFAM sigma-54 factor interaction domain-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CBS,HTH_8,PAS,Sigma54_activat
k59_131262_1	309800.C498_13213	6.37e-05	47.8	COG3385@1|root,arCOG03902@2157|Archaea	2157|Archaea	L	COG3385 FOG Transposase and inactivated derivatives	-	-	-	ko:K07495	-	-	-	-	ko00000	-	-	-	DDE_Tnp_1
k59_161572_1	948106.AWZT01000028_gene280	1.48e-10	67.0	COG0318@1|root,COG0318@2|Bacteria,1MUMC@1224|Proteobacteria,2VGZE@28216|Betaproteobacteria,1JZZ9@119060|Burkholderiaceae	28216|Betaproteobacteria	IQ	Activates fatty acids by binding to coenzyme A	alkK2	-	6.2.1.44	ko:K20034	ko00920,map00920	-	R10820	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C
k59_115744_1	761193.Runsl_0549	3.78e-77	249.0	COG1680@1|root,COG1680@2|Bacteria,4NEVS@976|Bacteroidetes,47NMR@768503|Cytophagia	976|Bacteroidetes	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
k59_100891_1	706587.Desti_2654	3.65e-28	112.0	COG0053@1|root,COG0053@2|Bacteria,1MUDS@1224|Proteobacteria,42NCJ@68525|delta/epsilon subdivisions,2WM7V@28221|Deltaproteobacteria,2MSIM@213462|Syntrophobacterales	28221|Deltaproteobacteria	P	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
k59_62995_2	1163671.JAGI01000002_gene2543	1.51e-10	63.2	COG0647@1|root,COG0647@2|Bacteria,1VDNE@1239|Firmicutes,24UBD@186801|Clostridia	186801|Clostridia	G	UMP catabolic process	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_168877_1	386456.JQKN01000002_gene2793	1.46e-49	167.0	arCOG02576@1|root,arCOG02576@2157|Archaea,2XZNM@28890|Euryarchaeota	28890|Euryarchaeota	S	NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
k59_123645_1	96561.Dole_1054	1.74e-49	181.0	COG1330@1|root,COG1330@2|Bacteria,1MWTI@1224|Proteobacteria,42N6G@68525|delta/epsilon subdivisions,2WJ4Q@28221|Deltaproteobacteria,2MHPX@213118|Desulfobacterales	28221|Deltaproteobacteria	L	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity	recC	-	3.1.11.5	ko:K03583	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_V_gamma
k59_184184_1	1265505.ATUG01000002_gene2503	4.83e-66	207.0	COG1410@1|root,COG1410@2|Bacteria,1MV6G@1224|Proteobacteria,42Q13@68525|delta/epsilon subdivisions,2WJHD@28221|Deltaproteobacteria,2MJ10@213118|Desulfobacterales	28221|Deltaproteobacteria	E	PFAM dihydropteroate synthase DHPS	-	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
k59_184184_2	1265505.ATUG01000002_gene2504	7.96e-09	55.1	COG5012@1|root,COG5012@2|Bacteria,1RDEU@1224|Proteobacteria,43BR3@68525|delta/epsilon subdivisions,2X7YW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM B12 binding domain	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,B12-binding_2
k59_40226_1	215803.DB30_8044	8.93e-54	177.0	COG1136@1|root,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,42QF5@68525|delta/epsilon subdivisions,2WK2K@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	PFAM ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
k59_63008_1	335543.Sfum_0797	3.38e-51	179.0	COG0633@1|root,COG3894@1|root,COG0633@2|Bacteria,COG3894@2|Bacteria,1MV6C@1224|Proteobacteria,42MF5@68525|delta/epsilon subdivisions,2WKC6@28221|Deltaproteobacteria,2MQU1@213462|Syntrophobacterales	68525|delta/epsilon subdivisions	C	PFAM 2Fe-2S iron-sulfur cluster binding domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4445,Fer2
k59_108311_1	269796.Rru_A1545	4.57e-05	50.1	COG2199@1|root,COG3706@2|Bacteria	2|Bacteria	T	GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS,PAS_3,PAS_4,PAS_8,PAS_9
k59_168902_1	1122237.AUGQ01000035_gene288	1.53e-20	92.4	COG0543@1|root,COG0543@2|Bacteria,2HQ24@201174|Actinobacteria	201174|Actinobacteria	C	electron transfer subunit	pyrK	-	-	ko:K02823	ko00240,ko01100,map00240,map01100	-	-	-	ko00000,ko00001	-	-	-	DHODB_Fe-S_bind,FAD_binding_6,NAD_binding_1
k59_176664_2	1121918.ARWE01000001_gene153	8.63e-100	296.0	COG0036@1|root,COG0036@2|Bacteria,1MUZM@1224|Proteobacteria,42NC0@68525|delta/epsilon subdivisions,2WJK9@28221|Deltaproteobacteria,43TEV@69541|Desulfuromonadales	28221|Deltaproteobacteria	G	Ribulose-phosphate 3 epimerase family	rpe	-	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
k59_85586_1	933262.AXAM01000106_gene2630	1.88e-150	441.0	COG1463@1|root,COG3008@1|root,COG1463@2|Bacteria,COG3008@2|Bacteria,1MU1T@1224|Proteobacteria,42PHS@68525|delta/epsilon subdivisions,2X5NU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	Q	PFAM Mammalian cell entry related domain protein	pqiB	-	-	ko:K06192	-	-	-	-	ko00000	-	-	-	MlaD
k59_85586_2	933262.AXAM01000106_gene2631	2.03e-06	48.5	COG2995@1|root,COG2995@2|Bacteria,1MWG1@1224|Proteobacteria,42R11@68525|delta/epsilon subdivisions,2WMWN@28221|Deltaproteobacteria,2MMZB@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Paraquat-inducible protein A	-	-	-	ko:K03808	-	-	-	-	ko00000	-	-	-	PqiA
k59_25008_1	1499967.BAYZ01000155_gene654	8.85e-81	258.0	COG0445@1|root,COG0445@2|Bacteria,2NNXQ@2323|unclassified Bacteria	2|Bacteria	D	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34	gidA	GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009451,GO:0009628,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0050896,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363	-	ko:K03495	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko03016,ko03036	-	-	-	GIDA,GIDA_assoc
k59_47817_1	743722.Sph21_4786	6.45e-08	59.7	COG4232@1|root,COG4232@2|Bacteria,4NIXX@976|Bacteroidetes,1IU4C@117747|Sphingobacteriia	976|Bacteroidetes	CO	Protein of unknown function, DUF255	-	-	-	-	-	-	-	-	-	-	-	-	Thioredox_DsbH,Thioredoxin,Thioredoxin_2,Thioredoxin_7
k59_9972_1	743299.Acife_2465	6.15e-35	132.0	COG0644@1|root,COG0644@2|Bacteria,1MXQY@1224|Proteobacteria,1SEJ8@1236|Gammaproteobacteria,2NCSM@225057|Acidithiobacillales	225057|Acidithiobacillales	C	FAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_2,FAD_binding_3,FAD_oxidored,Lycopene_cycl
k59_78265_1	1121405.dsmv_2119	1.14e-163	482.0	COG0466@1|root,COG0466@2|Bacteria,1MUV2@1224|Proteobacteria,42M9W@68525|delta/epsilon subdivisions,2WJ29@28221|Deltaproteobacteria,2MIDR@213118|Desulfobacterales	28221|Deltaproteobacteria	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon-3	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
k59_123669_1	371731.Rsw2DRAFT_1783	8.02e-63	211.0	COG1653@1|root,COG1653@2|Bacteria,1N8AS@1224|Proteobacteria,2U19M@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	ABC-type sugar transport system periplasmic component	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1,SBP_bac_8
k59_146318_1	1122243.KB903773_gene1331	2.57e-09	60.1	COG2201@1|root,COG2201@2|Bacteria,1N3V6@1224|Proteobacteria,1SATM@1236|Gammaproteobacteria,3NRM0@468|Moraxellaceae	1236|Gammaproteobacteria	NT	cheY-homologous receiver domain	-	-	3.1.1.61,3.5.1.44	ko:K03412,ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	Response_reg
k59_115784_1	1163407.UU7_05202	0.00084	42.0	COG0501@1|root,COG0501@2|Bacteria,1MUNA@1224|Proteobacteria,1RMZ6@1236|Gammaproteobacteria,1X48E@135614|Xanthomonadales	135614|Xanthomonadales	O	peptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
k59_78272_1	795666.MW7_3556	5.63e-20	86.3	COG0745@1|root,COG0745@2|Bacteria,1RDNP@1224|Proteobacteria,2VR8X@28216|Betaproteobacteria,1K6ZE@119060|Burkholderiaceae	28216|Betaproteobacteria	T	Chemotaxis regulator that, when phosphorylated, interacts with the flagellar motor causing the flagella to spin clockwise which causes the cell to tumble	cheY	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
k59_78272_2	879212.DespoDRAFT_00390	6.99e-46	158.0	COG1639@1|root,COG1639@2|Bacteria,1RKNA@1224|Proteobacteria,42TE8@68525|delta/epsilon subdivisions,2WPCE@28221|Deltaproteobacteria,2MPXW@213118|Desulfobacterales	28221|Deltaproteobacteria	T	HDOD domain	-	-	-	-	-	-	-	-	-	-	-	-	HDOD
k59_85593_1	1265505.ATUG01000002_gene2391	6.77e-56	180.0	COG0247@1|root,COG0247@2|Bacteria,1N5Q2@1224|Proteobacteria,42P5D@68525|delta/epsilon subdivisions,2WJ9I@28221|Deltaproteobacteria,2MI9D@213118|Desulfobacterales	28221|Deltaproteobacteria	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_17,Fer4_8,Fer4_9
k59_55493_1	225849.swp_3423	1.63e-40	154.0	COG2911@1|root,COG3897@1|root,COG5384@1|root,COG2911@2|Bacteria,COG3897@2|Bacteria,COG5384@2|Bacteria,1P8N9@1224|Proteobacteria	1224|Proteobacteria	MU	HemY domain protein	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Big_3_2,DUF1573,DUF5122,SWM_repeat
k59_78273_1	485915.Dret_1312	7.78e-36	132.0	COG1899@1|root,COG1899@2|Bacteria,1MVC6@1224|Proteobacteria,42QED@68525|delta/epsilon subdivisions,2WJWR@28221|Deltaproteobacteria,2MGJG@213115|Desulfovibrionales	28221|Deltaproteobacteria	O	Deoxyhypusine synthase	-	-	2.5.1.46	ko:K00809	-	-	-	-	ko00000,ko01000	-	-	-	DS
k59_17233_1	335543.Sfum_1361	6.26e-93	290.0	COG0481@1|root,COG0481@2|Bacteria,1MVZA@1224|Proteobacteria,42M3D@68525|delta/epsilon subdivisions,2WJEA@28221|Deltaproteobacteria,2MQ6G@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,EFG_II,GTP_EFTU,GTP_EFTU_D2,LepA_C
k59_222285_1	1217718.ALOU01000112_gene4314	6.26e-69	223.0	COG0671@1|root,COG0671@2|Bacteria,1PX74@1224|Proteobacteria,2WB1W@28216|Betaproteobacteria,1K4YH@119060|Burkholderiaceae	28216|Betaproteobacteria	I	LssY C-terminus	-	-	-	-	-	-	-	-	-	-	-	-	LssY_C
k59_176690_1	573413.Spirs_0343	2.86e-83	257.0	COG0683@1|root,COG0683@2|Bacteria,2J9IB@203691|Spirochaetes	203691|Spirochaetes	E	Receptor family ligand binding region	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
k59_176690_2	1121451.DESAM_21275	3.32e-06	50.8	COG0683@1|root,COG0683@2|Bacteria,1MWJ1@1224|Proteobacteria,42S3S@68525|delta/epsilon subdivisions,2WP0Z@28221|Deltaproteobacteria,2M9YG@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	Periplasmic binding protein domain	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
k59_100904_1	96561.Dole_0405	1.47e-27	107.0	COG0564@1|root,COG0564@2|Bacteria,1N8GW@1224|Proteobacteria,42QJY@68525|delta/epsilon subdivisions,2WK0U@28221|Deltaproteobacteria,2MK7F@213118|Desulfobacterales	28221|Deltaproteobacteria	J	RNA pseudouridylate synthase	-	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2
k59_100904_2	1121935.AQXX01000119_gene4774	6.44e-70	221.0	COG0462@1|root,COG0462@2|Bacteria,1MW21@1224|Proteobacteria,1RMUC@1236|Gammaproteobacteria,1XI6V@135619|Oceanospirillales	135619|Oceanospirillales	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	-	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran_N
k59_184233_1	933262.AXAM01000005_gene2537	1.86e-44	154.0	COG1344@1|root,COG1344@2|Bacteria,1MXC4@1224|Proteobacteria,42RME@68525|delta/epsilon subdivisions,2WN9Q@28221|Deltaproteobacteria	28221|Deltaproteobacteria	N	PFAM flagellin domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Flagellin_C,Flagellin_N
k59_229753_1	933262.AXAM01000019_gene1130	1.23e-38	138.0	COG1648@1|root,COG1648@2|Bacteria,1RB3H@1224|Proteobacteria,42QT2@68525|delta/epsilon subdivisions,2WN1F@28221|Deltaproteobacteria,2MJPS@213118|Desulfobacterales	28221|Deltaproteobacteria	H	TIGRFAM siroheme synthase	cysG	-	1.3.1.76,4.99.1.4	ko:K02304	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03947	RC01012,RC01034	ko00000,ko00001,ko00002,ko01000	-	-	-	NAD_binding_7,Sirohm_synth_M
k59_100905_1	665571.STHERM_c13300	1.11e-59	215.0	COG1391@1|root,COG1391@2|Bacteria	2|Bacteria	H	[glutamate-ammonia-ligase] adenylyltransferase activity	glnE	GO:0000820,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006521,GO:0008150,GO:0008882,GO:0010565,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0030312,GO:0031323,GO:0033238,GO:0040007,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0060359,GO:0062012,GO:0065007,GO:0070566,GO:0071944,GO:0080090,GO:1901698	2.7.7.42,2.7.7.89	ko:K00982	-	-	-	-	ko00000,ko01000	-	-	-	GlnD_UR_UTase,GlnE
k59_154541_2	1380391.JIAS01000012_gene4539	2.23e-10	62.0	2E53F@1|root,32ZWJ@2|Bacteria,1N6KB@1224|Proteobacteria,2TSI3@28211|Alphaproteobacteria,2JWRH@204441|Rhodospirillales	204441|Rhodospirillales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_162041_1	933262.AXAM01000055_gene1247	2.24e-05	53.1	COG1032@1|root,COG1032@2|Bacteria,1R4XI@1224|Proteobacteria,42NPM@68525|delta/epsilon subdivisions,2WJK2@28221|Deltaproteobacteria,2MI65@213118|Desulfobacterales	28221|Deltaproteobacteria	C	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
k59_237849_1	991905.SL003B_3848	3.43e-163	466.0	COG2801@1|root,COG2801@2|Bacteria,1MZ45@1224|Proteobacteria,2VFQ6@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	leucine-zipper of insertion element IS481	-	-	-	-	-	-	-	-	-	-	-	-	HTH_32,rve
k59_154545_1	1121405.dsmv_1094	4.78e-36	130.0	2CH0K@1|root,32S50@2|Bacteria,1N3TK@1224|Proteobacteria,42U5H@68525|delta/epsilon subdivisions,2WQPD@28221|Deltaproteobacteria,2MJVI@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_17724_1	693661.Arcve_1076	8.53e-07	51.2	COG1148@1|root,COG1908@1|root,arCOG02235@2157|Archaea,arCOG02476@2157|Archaea,2XT3X@28890|Euryarchaeota,245U1@183980|Archaeoglobi	183980|Archaeoglobi	C	Heterodisulfide reductase subunit A and related polyferredoxins	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,FlpD,Pyr_redox_2
k59_17724_2	1265505.ATUG01000002_gene2656	1.27e-37	129.0	COG1908@1|root,COG1908@2|Bacteria,1N4XV@1224|Proteobacteria,42UTE@68525|delta/epsilon subdivisions,2WQE3@28221|Deltaproteobacteria,2MKMT@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Methyl-viologen-reducing hydrogenase, delta subunit	-	-	-	-	-	-	-	-	-	-	-	-	FlpD
k59_124267_1	555778.Hneap_0971	1.09e-107	336.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,1RMYC@1236|Gammaproteobacteria,1WX32@135613|Chromatiales	135613|Chromatiales	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.6	ko:K01535	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.3.3	-	-	Cation_ATPase_N,E1-E2_ATPase,Hydrolase
k59_78693_1	556268.OFAG_00971	3.5e-07	57.0	COG0642@1|root,COG0745@1|root,COG0784@1|root,COG0745@2|Bacteria,COG0784@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,2VGZQ@28216|Betaproteobacteria,478DS@75682|Oxalobacteraceae	28216|Betaproteobacteria	T	Histidine kinase-like ATPases	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_9,Response_reg,dCache_1
k59_162046_1	933262.AXAM01000028_gene3342	5.2e-42	152.0	COG5433@1|root,COG5433@2|Bacteria,1MXI8@1224|Proteobacteria,42WFU@68525|delta/epsilon subdivisions,2WS4T@28221|Deltaproteobacteria,2MKX1@213118|Desulfobacterales	28221|Deltaproteobacteria	L	Pfam Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
k59_33000_1	1121405.dsmv_2738	3.76e-68	226.0	COG1185@1|root,COG1185@2|Bacteria,1MVB9@1224|Proteobacteria,42MTZ@68525|delta/epsilon subdivisions,2WJCE@28221|Deltaproteobacteria,2MIS9@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004654,GO:0005488,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
k59_237855_1	1121405.dsmv_0763	1.8e-114	348.0	COG1328@1|root,COG1328@2|Bacteria,1MWMS@1224|Proteobacteria,42M8V@68525|delta/epsilon subdivisions,2WJ7S@28221|Deltaproteobacteria,2MHTW@213118|Desulfobacterales	28221|Deltaproteobacteria	F	anaerobic ribonucleoside-triphosphate reductase	nrdD	-	1.1.98.6	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R11633,R11634,R11635,R11636	RC00613	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-cone,NRDD
k59_63484_1	768671.ThimaDRAFT_4530	1.6e-129	377.0	COG5421@1|root,COG5421@2|Bacteria,1R3NX@1224|Proteobacteria,1TKAD@1236|Gammaproteobacteria,1X15X@135613|Chromatiales	135613|Chromatiales	L	PFAM transposase, IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_101476_2	1121405.dsmv_1597	3.5e-28	111.0	COG0821@1|root,COG0821@2|Bacteria,1MUAX@1224|Proteobacteria,42M3V@68525|delta/epsilon subdivisions,2WJJ4@28221|Deltaproteobacteria,2MHT5@213118|Desulfobacterales	28221|Deltaproteobacteria	I	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate	ispG	GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576	1.17.7.1,1.17.7.3	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R08689,R10859	RC01486	ko00000,ko00001,ko00002,ko01000	-	-	-	GcpE
k59_139357_1	1394176.AWUO01000016_gene626	7.19e-28	129.0	COG5184@1|root,COG5184@2|Bacteria,2ID2P@201174|Actinobacteria,4D2SI@85004|Bifidobacteriales	201174|Actinobacteria	DZ	Listeria-Bacteroides repeat domain (List_Bact_rpt)	-	-	-	-	-	-	-	-	-	-	-	-	Flg_new,RCC1
k59_129744_2	96561.Dole_2642	2.82e-22	90.9	COG0071@1|root,COG0071@2|Bacteria,1NA27@1224|Proteobacteria,42VE3@68525|delta/epsilon subdivisions,2WR9Q@28221|Deltaproteobacteria,2MKAV@213118|Desulfobacterales	28221|Deltaproteobacteria	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
k59_137388_2	237368.SCABRO_02254	3.17e-10	60.1	COG3829@1|root,COG4191@1|root,COG3829@2|Bacteria,COG4191@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	ko:K02660,ko:K11525	ko02020,ko02025,map02020,map02025	-	-	-	ko00000,ko00001,ko02035,ko02044	-	-	-	7TMR-DISMED2,7TMR-DISM_7TM,EAL,GAF,GGDEF,HAMP,MCPsignal,PAS_3,PAS_4,PAS_7,dCache_1
k59_197996_2	1232437.KL662011_gene1494	3.02e-41	145.0	2CH0K@1|root,32S50@2|Bacteria,1N3TK@1224|Proteobacteria,42U5H@68525|delta/epsilon subdivisions,2WQPD@28221|Deltaproteobacteria,2MJVI@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_61699_1	941449.dsx2_1340	3.26e-48	161.0	COG1595@1|root,COG1595@2|Bacteria,1R9WC@1224|Proteobacteria,430GK@68525|delta/epsilon subdivisions,2WVVZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	Sigma-70, region 4	rpoE	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r4_2
k59_205651_1	40483.S8FX12	3.09e-07	54.3	COG0664@1|root,KOG1113@2759|Eukaryota,38GS1@33154|Opisthokonta,3NU9Z@4751|Fungi,3UZXM@5204|Basidiomycota,2273R@155619|Agaricomycetes,3H2BC@355688|Agaricomycetes incertae sedis	4751|Fungi	T	Camp-dependent protein kinase regulatory subunit	PKAR	GO:0000003,GO:0000228,GO:0000785,GO:0000790,GO:0001932,GO:0001933,GO:0002831,GO:0002832,GO:0003674,GO:0004857,GO:0004860,GO:0004862,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005694,GO:0005737,GO:0005886,GO:0006469,GO:0006950,GO:0006979,GO:0007154,GO:0008104,GO:0008150,GO:0008603,GO:0009266,GO:0009267,GO:0009405,GO:0009408,GO:0009605,GO:0009607,GO:0009628,GO:0009653,GO:0009892,GO:0009966,GO:0009968,GO:0009987,GO:0009991,GO:0010563,GO:0010570,GO:0010605,GO:0010639,GO:0010646,GO:0010648,GO:0016020,GO:0019207,GO:0019210,GO:0019220,GO:0019222,GO:0019887,GO:0019954,GO:0022603,GO:0023051,GO:0023057,GO:0030154,GO:0030234,GO:0030291,GO:0030435,GO:0030436,GO:0030447,GO:0030448,GO:0031279,GO:0031281,GO:0031323,GO:0031324,GO:0031399,GO:0031400,GO:0031667,GO:0031668,GO:0031669,GO:0031974,GO:0031981,GO:0032101,GO:0032102,GO:0032104,GO:0032105,GO:0032107,GO:0032108,GO:0032268,GO:0032269,GO:0032502,GO:0033036,GO:0033043,GO:0033554,GO:0033673,GO:0034305,GO:0034599,GO:0034605,GO:0034613,GO:0036170,GO:0036180,GO:0040007,GO:0040008,GO:0042173,GO:0042221,GO:0042325,GO:0042326,GO:0042594,GO:0043085,GO:0043086,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043549,GO:0043934,GO:0043936,GO:0043937,GO:0043938,GO:0043943,GO:0043945,GO:0044092,GO:0044093,GO:0044182,GO:0044419,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044446,GO:0044454,GO:0044464,GO:0045595,GO:0045597,GO:0045761,GO:0045762,GO:0045859,GO:0045881,GO:0045926,GO:0045936,GO:0046578,GO:0046580,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048585,GO:0048646,GO:0048856,GO:0048869,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051056,GO:0051058,GO:0051094,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051174,GO:0051179,GO:0051246,GO:0051248,GO:0051338,GO:0051339,GO:0051348,GO:0051349,GO:0051641,GO:0051704,GO:0051716,GO:0051783,GO:0051784,GO:0060255,GO:0060258,GO:0065007,GO:0065009,GO:0070013,GO:0070727,GO:0070887,GO:0071496,GO:0071900,GO:0071901,GO:0071944,GO:0080090,GO:0080134,GO:0097271,GO:0098772,GO:1900428,GO:1900429,GO:1900434,GO:1900435,GO:1900443,GO:1900444,GO:1902531,GO:1902532,GO:1903664,GO:1903666	-	ko:K04739	ko04910,map04910	-	-	-	ko00000,ko00001	-	-	-	RIIa,cNMP_binding
k59_23644_1	1125863.JAFN01000001_gene2573	2.06e-34	131.0	COG1283@1|root,COG1283@2|Bacteria,1MXWU@1224|Proteobacteria	1224|Proteobacteria	P	phosphate symporter	nptA	-	-	ko:K14683	-	-	-	-	ko00000,ko02000,ko04147	2.A.58.1	-	-	Na_Pi_cotrans
k59_84208_1	398767.Glov_1954	9.34e-28	119.0	COG1200@1|root,COG1200@2|Bacteria,1MWN2@1224|Proteobacteria,42NF8@68525|delta/epsilon subdivisions,2WKBA@28221|Deltaproteobacteria,43TAY@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
k59_31205_1	1232410.KI421413_gene956	2.57e-43	159.0	COG0768@1|root,COG0768@2|Bacteria,1MV8C@1224|Proteobacteria,42M1S@68525|delta/epsilon subdivisions,2WJ02@28221|Deltaproteobacteria,43RXD@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Penicillin-binding Protein dimerisation domain	mrdA	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	iAF987.Gmet_0928	PBP_dimer,Transpeptidase
k59_213088_1	63405.XP_002847942.1	6.68e-08	57.0	COG0456@1|root,KOG3139@2759|Eukaryota,38I1W@33154|Opisthokonta,3P3XV@4751|Fungi,3QPI2@4890|Ascomycota,20AE6@147545|Eurotiomycetes,3B0C3@33183|Onygenales,3FVWH@34384|Arthrodermataceae	4751|Fungi	S	Acetyltransferase (GNAT) domain	naa30	GO:0003674,GO:0003824,GO:0004596,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006473,GO:0006474,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0017196,GO:0018193,GO:0018206,GO:0019538,GO:0031248,GO:0031365,GO:0031414,GO:0031417,GO:0032879,GO:0032880,GO:0032991,GO:0034212,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0051604,GO:0065007,GO:0071704,GO:1901564,GO:1902493,GO:1902494,GO:1990234	2.3.1.256	ko:K00670	-	-	-	-	ko00000,ko01000,ko04131	-	-	-	Acetyltransf_1
k59_129762_1	1121405.dsmv_1877	1.48e-74	239.0	COG0318@1|root,COG0318@2|Bacteria,1MUMC@1224|Proteobacteria,42NT5@68525|delta/epsilon subdivisions,2WIWR@28221|Deltaproteobacteria,2MHQV@213118|Desulfobacterales	28221|Deltaproteobacteria	IQ	PFAM AMP-dependent synthetase and ligase	alkK	-	6.2.1.3	ko:K00666,ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
k59_114542_1	742733.HMPREF9469_02326	8.86e-06	52.4	COG0624@1|root,COG0624@2|Bacteria,1TQS9@1239|Firmicutes,24AXQ@186801|Clostridia,21XSU@1506553|Lachnoclostridium	186801|Clostridia	E	Psort location Cytoplasmic, score 8.87	argE	-	3.5.1.16	ko:K01438	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R00669,R09107	RC00064,RC00300	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
k59_235971_1	1282876.BAOK01000002_gene944	3.66e-92	279.0	COG0559@1|root,COG0559@2|Bacteria,1MVND@1224|Proteobacteria,2TRMA@28211|Alphaproteobacteria,4BREC@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
k59_182818_1	1304885.AUEY01000001_gene3210	1.39e-28	109.0	COG0293@1|root,COG0293@2|Bacteria,1MW1C@1224|Proteobacteria,42T4F@68525|delta/epsilon subdivisions,2WP6B@28221|Deltaproteobacteria,2MJST@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit	ftsJ	-	2.1.1.166	ko:K02427	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ
k59_182818_2	997296.PB1_06797	8.98e-34	129.0	COG1066@1|root,COG1066@2|Bacteria,1TQ7Y@1239|Firmicutes,4H9YC@91061|Bacilli,1ZB8H@1386|Bacillus	91061|Bacilli	O	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function	radA	-	-	ko:K04485	-	-	-	-	ko00000,ko03400	-	-	-	AAA_25,ATPase,ChlI
k59_213094_1	1121405.dsmv_2891	1.57e-46	156.0	COG0629@1|root,COG0629@2|Bacteria,1RCWT@1224|Proteobacteria,42TV9@68525|delta/epsilon subdivisions,2WNAN@28221|Deltaproteobacteria,2MK10@213118|Desulfobacterales	28221|Deltaproteobacteria	L	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism	ssb	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
k59_76864_1	663278.Ethha_1051	2.27e-21	97.8	COG3850@1|root,COG5002@1|root,COG3850@2|Bacteria,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,247VG@186801|Clostridia,3WG93@541000|Ruminococcaceae	186801|Clostridia	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
k59_76864_2	1185653.A1A1_10941	1.99e-08	55.1	COG0745@1|root,COG0745@2|Bacteria,1TX0Q@1239|Firmicutes,4HEF8@91061|Bacilli,26CU7@186818|Planococcaceae	91061|Bacilli	T	Transcriptional regulatory protein, C terminal	yvrH	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
k59_183301_1	1125863.JAFN01000001_gene163	7.7e-92	287.0	COG1022@1|root,COG1022@2|Bacteria,1MU4D@1224|Proteobacteria,42N2G@68525|delta/epsilon subdivisions,2WIXB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	PFAM AMP-dependent synthetase and ligase	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
k59_107476_1	335543.Sfum_0209	5.82e-64	211.0	COG1007@1|root,COG1007@2|Bacteria,1MV56@1224|Proteobacteria,42P7Z@68525|delta/epsilon subdivisions,2WKS0@28221|Deltaproteobacteria,2MQ9R@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
k59_16484_1	879212.DespoDRAFT_00616	1.97e-56	191.0	COG2204@1|root,COG2206@1|root,COG2204@2|Bacteria,COG2206@2|Bacteria,1RAQS@1224|Proteobacteria,42MEJ@68525|delta/epsilon subdivisions,2X71A@28221|Deltaproteobacteria,2MHS0@213118|Desulfobacterales	28221|Deltaproteobacteria	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GAF_3,GGDEF,HD,Response_reg
k59_190861_2	1121405.dsmv_3379	1.92e-43	142.0	COG0695@1|root,COG0695@2|Bacteria,1NAZM@1224|Proteobacteria,42VIA@68525|delta/epsilon subdivisions,2WR8X@28221|Deltaproteobacteria,2MKPI@213118|Desulfobacterales	28221|Deltaproteobacteria	O	PFAM Glutaredoxin	-	-	-	ko:K06191	-	-	-	-	ko00000	-	-	-	Glutaredoxin
k59_137949_1	1173020.Cha6605_3962	1.27e-35	124.0	COG2346@1|root,COG2346@2|Bacteria	2|Bacteria	O	COG2346, Truncated hemoglobins	glbN	-	-	ko:K06886	-	-	-	-	ko00000	-	-	-	Bac_globin
k59_236509_1	472759.Nhal_1238	6.53e-88	270.0	COG1215@1|root,COG1215@2|Bacteria,1MW1E@1224|Proteobacteria,1RZY2@1236|Gammaproteobacteria,1X091@135613|Chromatiales	135613|Chromatiales	M	Glycosyl transferase family 21	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3
k59_46898_1	335543.Sfum_3111	1.73e-72	232.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M2X@68525|delta/epsilon subdivisions,2WJMY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
k59_198513_1	439235.Dalk_0106	5.25e-96	297.0	COG1960@1|root,COG1960@2|Bacteria,1MU20@1224|Proteobacteria,42YAX@68525|delta/epsilon subdivisions,2WU3C@28221|Deltaproteobacteria,2MMI7@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM acyl-CoA dehydrogenase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_C,Acyl-CoA_dh_M,Acyl-CoA_dh_N,AcylCoA_DH_N
k59_213648_1	1121406.JAEX01000005_gene2868	2.62e-70	227.0	COG0683@1|root,COG0683@2|Bacteria,1MWR8@1224|Proteobacteria,42NI3@68525|delta/epsilon subdivisions,2WJ6P@28221|Deltaproteobacteria,2M856@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	PFAM Extracellular ligand-binding receptor	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_6
k59_122747_1	1121405.dsmv_0036	4.45e-154	461.0	COG0060@1|root,COG0060@2|Bacteria,1MVBQ@1224|Proteobacteria,42MKB@68525|delta/epsilon subdivisions,2WJ4W@28221|Deltaproteobacteria,2MI4Z@213118|Desulfobacterales	28221|Deltaproteobacteria	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1,zf-FPG_IleRS
k59_84693_1	244447.XP_008327626.1	1.77e-09	60.1	COG0318@1|root,KOG1177@2759|Eukaryota,38ES8@33154|Opisthokonta,3BHR0@33208|Metazoa,3CTUM@33213|Bilateria,48AEJ@7711|Chordata,48ZGR@7742|Vertebrata,49SX8@7898|Actinopterygii	33208|Metazoa	I	acyl-CoA synthetase family member 2	ACSF2	GO:0003674,GO:0003824,GO:0003996,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005777,GO:0006082,GO:0006139,GO:0006163,GO:0006629,GO:0006631,GO:0006633,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0015645,GO:0016053,GO:0016405,GO:0016874,GO:0016877,GO:0016878,GO:0019637,GO:0019693,GO:0019752,GO:0031974,GO:0032787,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0055086,GO:0070013,GO:0071704,GO:0072330,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901576	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
k59_84693_2	1123288.SOV_5c00660	3.1e-66	218.0	COG0318@1|root,COG0318@2|Bacteria,1TPSX@1239|Firmicutes,4H6ZM@909932|Negativicutes	909932|Negativicutes	IQ	AMP-binding enzyme C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
k59_62222_1	768671.ThimaDRAFT_0226	8.12e-136	398.0	COG3119@1|root,COG3119@2|Bacteria,1MUJH@1224|Proteobacteria,1RN2V@1236|Gammaproteobacteria,1WVZV@135613|Chromatiales	135613|Chromatiales	P	PFAM Sulfatase	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase,Sulfatase_C
k59_46910_1	420246.GTNG_2705	4.33e-19	90.5	COG1893@1|root,COG1893@2|Bacteria,1UM1M@1239|Firmicutes,4HBPD@91061|Bacilli	91061|Bacilli	H	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid	apbA	-	1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000	-	-	-	ApbA,ApbA_C
k59_100008_1	1121405.dsmv_3251	2.07e-71	237.0	COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,42N8M@68525|delta/epsilon subdivisions,2WJRT@28221|Deltaproteobacteria,2MHZG@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	-	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	LAGLIDADG_3,Ribonuc_red_lgC,Ribonuc_red_lgN,TSCPD
k59_31706_1	1232410.KI421412_gene372	2.35e-14	74.7	COG2204@1|root,COG2204@2|Bacteria,1MVWX@1224|Proteobacteria,42MIB@68525|delta/epsilon subdivisions,2WJQK@28221|Deltaproteobacteria,43TXT@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Sigma-54 interaction domain	-	-	-	ko:K02481	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Sigma54_activat
k59_8972_1	1121405.dsmv_1994	1.15e-68	210.0	COG0838@1|root,COG0838@2|Bacteria,1RGUT@1224|Proteobacteria,42U92@68525|delta/epsilon subdivisions,2WQCK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoA	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0050136,GO:0055114,GO:0098796,GO:1902494	1.6.5.3	ko:K00330	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q4
k59_153183_1	1121396.KB893053_gene2382	1.09e-55	186.0	COG0142@1|root,COG0142@2|Bacteria,1MUK6@1224|Proteobacteria,42M1B@68525|delta/epsilon subdivisions,2WK2M@28221|Deltaproteobacteria,2MJ27@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Belongs to the FPP GGPP synthase family	ispB	-	2.5.1.1,2.5.1.10,2.5.1.29,2.5.1.90	ko:K02523,ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00366	R01658,R02003,R02061,R09248	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
k59_183329_2	1121405.dsmv_3379	4.25e-40	134.0	COG0695@1|root,COG0695@2|Bacteria,1NAZM@1224|Proteobacteria,42VIA@68525|delta/epsilon subdivisions,2WR8X@28221|Deltaproteobacteria,2MKPI@213118|Desulfobacterales	28221|Deltaproteobacteria	O	PFAM Glutaredoxin	-	-	-	ko:K06191	-	-	-	-	ko00000	-	-	-	Glutaredoxin
k59_100028_1	177439.DP1987	3.1e-18	84.0	COG0210@1|root,COG0507@1|root,COG0210@2|Bacteria,COG0507@2|Bacteria,1QCFP@1224|Proteobacteria,42NH5@68525|delta/epsilon subdivisions,2WKAR@28221|Deltaproteobacteria,2MHPD@213118|Desulfobacterales	28221|Deltaproteobacteria	L	Helix-turn-helix domain	-	-	3.6.4.12	ko:K15255	-	-	-	-	ko00000,ko01000,ko03029,ko03032	-	-	-	HRDC,HTH_40,Herpes_Helicase,PIF1
k59_77371_1	1121405.dsmv_2841	4.45e-09	55.8	COG4747@1|root,COG4747@2|Bacteria,1RDCG@1224|Proteobacteria,42RTD@68525|delta/epsilon subdivisions,2WQBM@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM amino acid-binding ACT domain protein	-	-	-	-	-	-	-	-	-	-	-	-	ACT
k59_77371_2	264732.Moth_2412	5.71e-28	110.0	COG2876@1|root,COG2876@2|Bacteria,1TP61@1239|Firmicutes,24812@186801|Clostridia,42EJY@68295|Thermoanaerobacterales	186801|Clostridia	E	DAHP synthetase I family	-	-	2.5.1.54	ko:K03856	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_1
k59_168111_1	1232437.KL661976_gene4970	2.4e-107	325.0	COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,42M88@68525|delta/epsilon subdivisions,2WIZI@28221|Deltaproteobacteria,2MJ2S@213118|Desulfobacterales	28221|Deltaproteobacteria	T	PFAM sigma-54 factor interaction domain-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,PAS_9,Sigma54_activat
k59_1343_1	743974.MBO_01375	2.11e-46	166.0	COG0836@1|root,COG0836@2|Bacteria,1MV39@1224|Proteobacteria,1RNQI@1236|Gammaproteobacteria,3NMRW@468|Moraxellaceae	1236|Gammaproteobacteria	M	Belongs to the mannose-6-phosphate isomerase type 2 family	cpsB	-	2.7.7.13,5.3.1.8	ko:K00971,ko:K16011	ko00051,ko00520,ko01100,ko01110,ko01130,ko02025,map00051,map00520,map01100,map01110,map01130,map02025	M00114,M00361,M00362	R00885,R01819	RC00002,RC00376	ko00000,ko00001,ko00002,ko01000	-	-	-	MannoseP_isomer,NTP_transferase
k59_1345_1	1121405.dsmv_1830	2.33e-76	241.0	COG0303@1|root,COG0303@2|Bacteria,1MVD5@1224|Proteobacteria,42PWY@68525|delta/epsilon subdivisions,2WKFX@28221|Deltaproteobacteria,2MJ9Z@213118|Desulfobacterales	28221|Deltaproteobacteria	H	MoeA N-terminal region (domain I and II)	-	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
k59_39368_1	526222.Desal_3220	2.06e-103	321.0	COG0145@1|root,COG0145@2|Bacteria,1MU2Y@1224|Proteobacteria,42NFP@68525|delta/epsilon subdivisions,2WK64@28221|Deltaproteobacteria,2M9T7@213115|Desulfovibrionales	28221|Deltaproteobacteria	EQ	PFAM Hydantoinase oxoprolinase	hyuA	-	3.5.2.14	ko:K01473	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydant_A_N,Hydantoinase_A
k59_145535_1	1121405.dsmv_1111	2.49e-139	404.0	COG0115@1|root,COG0115@2|Bacteria,1MVB0@1224|Proteobacteria,42MKX@68525|delta/epsilon subdivisions,2WJ7X@28221|Deltaproteobacteria,2MIWF@213118|Desulfobacterales	28221|Deltaproteobacteria	E	TIGRFAM branched-chain amino acid aminotransferase	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	iAF987.Gmet_2853	Aminotran_4
k59_39370_1	690850.Desaf_1773	1.34e-05	48.9	COG1253@1|root,COG1253@2|Bacteria,1MV3P@1224|Proteobacteria,42N97@68525|delta/epsilon subdivisions,2WKVE@28221|Deltaproteobacteria,2M7ZJ@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Transporter-associated region	-	-	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	CBS,CorC_HlyC,DUF21
k59_39370_2	945713.IALB_3005	8.03e-49	167.0	COG0598@1|root,COG0598@2|Bacteria	2|Bacteria	P	Magnesium transport protein CorA	corA	GO:0000041,GO:0000287,GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006824,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015087,GO:0015095,GO:0015318,GO:0015693,GO:0016020,GO:0016021,GO:0016043,GO:0022607,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0031226,GO:0034220,GO:0042802,GO:0043167,GO:0043169,GO:0043933,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0046872,GO:0046873,GO:0046914,GO:0046915,GO:0050897,GO:0051179,GO:0051234,GO:0051259,GO:0051260,GO:0055085,GO:0065003,GO:0070838,GO:0071840,GO:0071944,GO:0072511,GO:0098655,GO:0098660,GO:0098662,GO:1903830	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
k59_9009_1	1499967.BAYZ01000048_gene2700	1.89e-90	279.0	COG2211@1|root,COG2211@2|Bacteria	2|Bacteria	G	Major facilitator Superfamily	-	-	-	ko:K03292	-	-	-	-	ko00000	2.A.2	-	-	MFS_2,MFS_3
k59_137981_1	314230.DSM3645_29267	4.07e-11	70.1	COG0006@1|root,COG0006@2|Bacteria,2J3P5@203682|Planctomycetes	203682|Planctomycetes	E	Aminopeptidase P, N-terminal domain	-	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	AMP_N,Peptidase_M24
k59_168114_1	1121405.dsmv_0555	4.78e-81	261.0	COG0507@1|root,COG0507@2|Bacteria,1MW43@1224|Proteobacteria,42M8J@68525|delta/epsilon subdivisions,2WJD6@28221|Deltaproteobacteria,2MINC@213118|Desulfobacterales	28221|Deltaproteobacteria	L	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity	recD2	-	3.1.11.5	ko:K03581	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AAA_30,HHH_4,HHH_5,UvrD_C_2
k59_206191_1	933262.AXAM01000053_gene2716	2.43e-69	219.0	COG1355@1|root,COG1355@2|Bacteria,1MXK5@1224|Proteobacteria,42R55@68525|delta/epsilon subdivisions,2WKKG@28221|Deltaproteobacteria,2MJ1F@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Memo-like protein	-	-	-	ko:K06990	-	-	-	-	ko00000,ko04812	-	-	-	Memo
k59_213696_1	335543.Sfum_0122	1.3e-237	682.0	COG0060@1|root,COG0060@2|Bacteria,1MVBQ@1224|Proteobacteria,42MKB@68525|delta/epsilon subdivisions,2WJ4W@28221|Deltaproteobacteria,2MQ7V@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1,zf-FPG_IleRS
k59_16510_1	742735.HMPREF9467_01740	4.68e-24	103.0	COG1947@1|root,COG1947@2|Bacteria,1TPXV@1239|Firmicutes,24898@186801|Clostridia,21Y9Z@1506553|Lachnoclostridium	186801|Clostridia	F	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol	ispE	-	2.7.1.148	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05634	RC00002,RC01439	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
k59_122822_1	933262.AXAM01000066_gene1688	8.58e-43	154.0	COG0739@1|root,COG0739@2|Bacteria,1NESH@1224|Proteobacteria,42MGB@68525|delta/epsilon subdivisions,2WJ7F@28221|Deltaproteobacteria,2MI1U@213118|Desulfobacterales	28221|Deltaproteobacteria	M	PFAM peptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
k59_130454_1	56780.SYN_02153	4.63e-90	278.0	COG1220@1|root,COG1220@2|Bacteria,1MVK9@1224|Proteobacteria,42M48@68525|delta/epsilon subdivisions,2WISV@28221|Deltaproteobacteria,2MQ63@213462|Syntrophobacterales	28221|Deltaproteobacteria	O	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis	hslU	-	-	ko:K03667	-	-	-	-	ko00000,ko03110	-	-	-	AAA_2,ClpB_D2-small
k59_213719_1	335543.Sfum_0263	3.32e-137	413.0	COG0542@1|root,COG0542@2|Bacteria,1MURH@1224|Proteobacteria,42M9S@68525|delta/epsilon subdivisions,2WJSZ@28221|Deltaproteobacteria,2MQ8A@213462|Syntrophobacterales	28221|Deltaproteobacteria	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
k59_206209_1	1121405.dsmv_0470	4.33e-61	203.0	COG1680@1|root,COG1680@2|Bacteria,1QUYZ@1224|Proteobacteria,42PUC@68525|delta/epsilon subdivisions,2WK0V@28221|Deltaproteobacteria,2MIWD@213118|Desulfobacterales	28221|Deltaproteobacteria	V	PFAM Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
k59_183355_1	1265505.ATUG01000003_gene724	1.55e-109	326.0	COG0446@1|root,COG0446@2|Bacteria,1QSGB@1224|Proteobacteria,43A36@68525|delta/epsilon subdivisions,2WZXC@28221|Deltaproteobacteria,2MP72@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.5.4	ko:K17218	ko00920,map00920	-	R10152	RC03155	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
k59_206211_1	1121405.dsmv_2171	1.61e-78	246.0	COG0743@1|root,COG0743@2|Bacteria,1MU4G@1224|Proteobacteria,42NI1@68525|delta/epsilon subdivisions,2WK14@28221|Deltaproteobacteria,2MIFC@213118|Desulfobacterales	28221|Deltaproteobacteria	I	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)	dxr	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576	1.1.1.267	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05688	RC01452	ko00000,ko00001,ko00002,ko01000	-	-	-	DXPR_C,DXP_redisom_C,DXP_reductoisom
k59_233640_2	1121456.ATVA01000001_gene3069	2.69e-41	150.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WJKZ@28221|Deltaproteobacteria,2MGPR@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	Bacterial regulatory protein, Fis family	-	-	-	ko:K07713	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
k59_240393_2	1123277.KB893177_gene3616	3.79e-16	75.1	COG1595@1|root,COG1595@2|Bacteria,4NQPI@976|Bacteroidetes,47RJK@768503|Cytophagia	976|Bacteroidetes	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
k59_142505_1	595460.RRSWK_02599	1.79e-14	74.7	COG2020@1|root,COG2020@2|Bacteria,2J4DN@203682|Planctomycetes	203682|Planctomycetes	O	Phospholipid methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
k59_119004_1	1265505.ATUG01000002_gene1738	3.05e-37	141.0	COG0145@1|root,COG0145@2|Bacteria,1MU2Y@1224|Proteobacteria,42MSS@68525|delta/epsilon subdivisions,2WIN2@28221|Deltaproteobacteria,2MJC2@213118|Desulfobacterales	28221|Deltaproteobacteria	EQ	Hydantoinase/oxoprolinase	-	-	-	-	-	-	-	-	-	-	-	-	DUF1638,Hydant_A_N,Hydantoinase_A
k59_119004_2	1120999.JONM01000011_gene1605	5.64e-36	125.0	COG1917@1|root,COG1917@2|Bacteria,1RH1V@1224|Proteobacteria,2VPZH@28216|Betaproteobacteria,2KT2F@206351|Neisseriales	206351|Neisseriales	S	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
k59_172503_1	177437.HRM2_26100	3.77e-72	235.0	COG0515@1|root,COG0664@1|root,COG0515@2|Bacteria,COG0664@2|Bacteria,1MV1P@1224|Proteobacteria,42Q67@68525|delta/epsilon subdivisions,2WKZ1@28221|Deltaproteobacteria,2MHTH@213118|Desulfobacterales	28221|Deltaproteobacteria	KLT	PFAM Protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	CHASE2,Pkinase,cNMP_binding
k59_43101_1	1232410.KI421418_gene2271	6.16e-10	57.0	2BNIW@1|root,32H7I@2|Bacteria,1Q1B7@1224|Proteobacteria,43761@68525|delta/epsilon subdivisions,2X24F@28221|Deltaproteobacteria,43SSX@69541|Desulfuromonadales	28221|Deltaproteobacteria	-	-	-	-	-	ko:K09794	-	-	-	-	ko00000	-	-	-	-
k59_43101_2	1121403.AUCV01000008_gene1553	2.73e-15	75.1	COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,42M1X@68525|delta/epsilon subdivisions,2WJA2@28221|Deltaproteobacteria,2MHZK@213118|Desulfobacterales	28221|Deltaproteobacteria	EH	TIGRFAM acetolactate synthase, large subunit, biosynthetic type	ilvB	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
k59_59141_1	933262.AXAM01000028_gene3307	1.66e-98	298.0	COG0148@1|root,COG0148@2|Bacteria,1MU1N@1224|Proteobacteria,42MS9@68525|delta/epsilon subdivisions,2WJMS@28221|Deltaproteobacteria,2MI3S@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
k59_59141_2	909663.KI867149_gene3363	1.36e-52	179.0	COG0033@1|root,COG0033@2|Bacteria,1MU5S@1224|Proteobacteria,42M9F@68525|delta/epsilon subdivisions,2WJNB@28221|Deltaproteobacteria,2MQ6U@213462|Syntrophobacterales	28221|Deltaproteobacteria	G	Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III	pgm	-	5.4.2.2	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00549	R00959,R01057,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
k59_127226_1	472759.Nhal_0304	4.62e-67	216.0	COG2230@1|root,COG2230@2|Bacteria,1MUW5@1224|Proteobacteria,1RPUC@1236|Gammaproteobacteria,1WWIX@135613|Chromatiales	135613|Chromatiales	M	Mycolic acid cyclopropane synthetase	-	-	2.1.1.79	ko:K00574	-	-	-	-	ko00000,ko01000	-	-	-	CMAS
k59_210746_1	880072.Desac_0834	2.94e-108	342.0	COG1145@1|root,COG1148@1|root,COG1145@2|Bacteria,COG1148@2|Bacteria,1QUM4@1224|Proteobacteria,42MPP@68525|delta/epsilon subdivisions,2WJ3U@28221|Deltaproteobacteria,2MQVU@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	4Fe-4S ferredoxin iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_20,Pyr_redox_2
k59_194700_1	411469.EUBHAL_00748	1.98e-14	70.5	COG0131@1|root,COG0131@2|Bacteria,1TRH7@1239|Firmicutes,247WC@186801|Clostridia,25VZA@186806|Eubacteriaceae	186801|Clostridia	E	imidazoleglycerol-phosphate dehydratase	hisB	-	4.2.1.19	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03457	RC00932	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPD
k59_194700_2	1265505.ATUG01000001_gene3302	1.94e-15	76.3	COG0457@1|root,COG1944@1|root,COG0457@2|Bacteria,COG1944@2|Bacteria,1MV7K@1224|Proteobacteria,42N4B@68525|delta/epsilon subdivisions,2WJ34@28221|Deltaproteobacteria,2MHRU@213118|Desulfobacterales	28221|Deltaproteobacteria	S	YcaO cyclodehydratase, ATP-ad Mg2+-binding	-	-	-	ko:K09136	-	-	-	-	ko00000,ko03009	-	-	-	TPR_1,TPR_16,TPR_2,TPR_8,YcaO
k59_119010_1	319795.Dgeo_0886	7.15e-69	218.0	COG0479@1|root,COG0479@2|Bacteria,1WIEW@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein	-	-	1.3.5.1,1.3.5.4	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_3,Fer4_10,Fer4_8
k59_188158_1	1265505.ATUG01000003_gene211	7.71e-67	226.0	COG0517@1|root,COG0617@1|root,COG0618@1|root,COG0517@2|Bacteria,COG0617@2|Bacteria,COG0618@2|Bacteria,1MU2X@1224|Proteobacteria,42MJJ@68525|delta/epsilon subdivisions,2WJBN@28221|Deltaproteobacteria,2MI4C@213118|Desulfobacterales	28221|Deltaproteobacteria	J	CBS domain	ccaA	-	2.7.7.72	ko:K00974	ko03013,map03013	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016	-	-	-	CBS,DHH,DHHA1,PolyA_pol,PolyA_pol_RNAbd
k59_89025_1	96561.Dole_2151	2.83e-34	136.0	COG0568@1|root,COG0568@2|Bacteria,1MVNJ@1224|Proteobacteria,42N2S@68525|delta/epsilon subdivisions,2WJ0E@28221|Deltaproteobacteria,2MHX2@213118|Desulfobacterales	28221|Deltaproteobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	rpoD	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_ner,Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
k59_149239_1	870967.VIS19158_02350	3.02e-41	154.0	COG1574@1|root,COG1574@2|Bacteria,1MWP2@1224|Proteobacteria,1RNB7@1236|Gammaproteobacteria,1XTUF@135623|Vibrionales	135623|Vibrionales	S	metal-dependent hydrolase with the TIM-barrel fold	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
k59_112003_1	56780.SYN_01990	3.41e-59	197.0	COG2256@1|root,COG2256@2|Bacteria,1MUVS@1224|Proteobacteria,42M9X@68525|delta/epsilon subdivisions,2WJ7E@28221|Deltaproteobacteria,2MQ8K@213462|Syntrophobacterales	28221|Deltaproteobacteria	L	PFAM MgsA AAA ATPase C terminal	rarA	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA,AAA_assoc_2,MgsA_C,RuvB_N
k59_240422_1	335543.Sfum_0020	8.2e-103	321.0	COG1067@1|root,COG1067@2|Bacteria,1MWGB@1224|Proteobacteria,42NJD@68525|delta/epsilon subdivisions,2WJFK@28221|Deltaproteobacteria,2MQ92@213462|Syntrophobacterales	28221|Deltaproteobacteria	O	Belongs to the peptidase S16 family	-	-	3.4.21.53	ko:K01338,ko:K04076	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA_32,Lon_C
k59_73997_1	338963.Pcar_0105	1.81e-29	123.0	COG0683@1|root,COG0683@2|Bacteria,1R8IG@1224|Proteobacteria,42N7H@68525|delta/epsilon subdivisions,2WIUQ@28221|Deltaproteobacteria,43S82@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	LppC putative lipoprotein	-	-	-	ko:K07121	-	-	-	-	ko00000	-	-	-	LppC,Peripla_BP_6,TPR_16,TPR_6
k59_81698_1	945713.IALB_1619	4.5e-47	163.0	COG0836@1|root,COG0836@2|Bacteria	2|Bacteria	M	mannose-1-phosphate guanylyltransferase activity	manC	-	2.7.7.13,5.3.1.8,5.4.2.8	ko:K00971,ko:K01840,ko:K16011	ko00051,ko00520,ko01100,ko01110,ko01130,ko02025,map00051,map00520,map01100,map01110,map01130,map02025	M00114,M00361,M00362	R00885,R01818,R01819	RC00002,RC00376,RC00408	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS00940	MannoseP_isomer,NTP_transferase
k59_210753_1	401526.TcarDRAFT_0347	1.48e-05	49.7	COG0859@1|root,COG0859@2|Bacteria,1UZZI@1239|Firmicutes,4H2VC@909932|Negativicutes	909932|Negativicutes	M	PFAM glycosyl transferase family 9	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_9
k59_194719_2	96561.Dole_2335	7.21e-89	273.0	COG0745@1|root,COG0745@2|Bacteria,1NE8H@1224|Proteobacteria,42NEH@68525|delta/epsilon subdivisions,2WK1M@28221|Deltaproteobacteria,2MHU4@213118|Desulfobacterales	28221|Deltaproteobacteria	T	PFAM response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Cytidylate_kin2,Response_reg
k59_240429_1	1049564.TevJSym_af00930	6.09e-53	180.0	COG1639@1|root,COG2204@1|root,COG1639@2|Bacteria,COG2204@2|Bacteria,1RCW6@1224|Proteobacteria,1S3XV@1236|Gammaproteobacteria,1J6BK@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	T	HDOD domain	-	-	-	-	-	-	-	-	-	-	-	-	HDOD,Response_reg
k59_20562_2	1123075.AUDP01000007_gene2771	2.12e-89	270.0	COG0491@1|root,COG0491@2|Bacteria,1TRED@1239|Firmicutes,24P8Q@186801|Clostridia,3WP4A@541000|Ruminococcaceae	186801|Clostridia	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
k59_240432_1	536227.CcarbDRAFT_3899	8.03e-27	111.0	COG0536@1|root,COG0536@2|Bacteria,1TPX7@1239|Firmicutes,247SP@186801|Clostridia,36DEA@31979|Clostridiaceae	186801|Clostridia	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	-	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	DUF1967,GTP1_OBG,MMR_HSR1
k59_240433_1	1121459.AQXE01000002_gene1363	2.53e-37	140.0	COG3075@1|root,COG3075@2|Bacteria,1MU3K@1224|Proteobacteria,42Q09@68525|delta/epsilon subdivisions,2WKE0@28221|Deltaproteobacteria,2M7WY@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	Glycerol-3-phosphate dehydrogenase, anaerobic, B subunit	-	-	1.1.5.3	ko:K00112	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	FAD_binding_2
k59_217886_1	1379698.RBG1_1C00001G0230	7.09e-77	250.0	COG2206@1|root,COG2206@2|Bacteria,2NPP4@2323|unclassified Bacteria	2|Bacteria	T	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	-	-	-	-	-	-	-	-	-	HD
k59_27917_1	1499967.BAYZ01000048_gene2696	2.14e-79	249.0	COG2230@1|root,COG2230@2|Bacteria	2|Bacteria	M	cyclopropane-fatty-acyl-phospholipid synthase	cfa	-	2.1.1.317,2.1.1.79	ko:K00574,ko:K20238	-	-	-	-	ko00000,ko01000	-	-	iJN746.PP_2734	CMAS
k59_179606_1	1304885.AUEY01000028_gene2790	1.47e-97	293.0	COG0150@1|root,COG0150@2|Bacteria,1MURG@1224|Proteobacteria,42KZT@68525|delta/epsilon subdivisions,2WIXY@28221|Deltaproteobacteria,2MHNK@213118|Desulfobacterales	28221|Deltaproteobacteria	F	PFAM AIR synthase related protein	purM	-	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1844	AIRS,AIRS_C
k59_43116_1	1528106.JRJE01000008_gene1507	2.31e-45	160.0	COG3875@1|root,COG3875@2|Bacteria,1R79Y@1224|Proteobacteria,2U4VR@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Domain of unknown function (DUF2088)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2088
k59_225303_1	1121405.dsmv_0479	2e-104	315.0	COG0056@1|root,COG0056@2|Bacteria,1MUG7@1224|Proteobacteria,42MVX@68525|delta/epsilon subdivisions,2WIK7@28221|Deltaproteobacteria,2MIHR@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
k59_4774_1	1265505.ATUG01000003_gene569	4.23e-58	190.0	COG0697@1|root,COG0697@2|Bacteria,1MZXM@1224|Proteobacteria,42ME7@68525|delta/epsilon subdivisions,2WSJG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
k59_172519_1	933262.AXAM01000010_gene1387	2.62e-84	263.0	COG0056@1|root,COG0056@2|Bacteria,1MUG7@1224|Proteobacteria,42MVX@68525|delta/epsilon subdivisions,2WIK7@28221|Deltaproteobacteria,2MIHR@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
k59_59206_1	439235.Dalk_4215	2.37e-18	80.5	28YYF@1|root,2ZKRD@2|Bacteria,1P9QW@1224|Proteobacteria,4331B@68525|delta/epsilon subdivisions,2WYDC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_179615_1	106370.Francci3_3631	1.68e-06	53.5	COG0115@1|root,COG0115@2|Bacteria,2GKJ1@201174|Actinobacteria	201174|Actinobacteria	E	Branched-chain amino acid aminotransferase	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
k59_20588_1	436308.Nmar_1792	2.61e-75	243.0	COG0459@1|root,arCOG01257@2157|Archaea,41SDG@651137|Thaumarchaeota	651137|Thaumarchaeota	O	PFAM TCP-1 cpn60 chaperonin family	-	-	-	ko:K22447	-	-	-	-	ko00000,ko03110	-	-	-	Cpn60_TCP1
k59_179617_2	1121396.KB893063_gene1201	4.24e-17	82.8	COG2984@1|root,COG2984@2|Bacteria,1R84M@1224|Proteobacteria,42PKD@68525|delta/epsilon subdivisions,2WMBV@28221|Deltaproteobacteria,2MJYP@213118|Desulfobacterales	28221|Deltaproteobacteria	S	ABC transporter substrate binding protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC_sub_bind
k59_59210_1	555779.Dthio_PD2257	5.61e-171	493.0	COG1032@1|root,COG1032@2|Bacteria,1MY2Y@1224|Proteobacteria,42NG3@68525|delta/epsilon subdivisions,2WJ95@28221|Deltaproteobacteria,2M84C@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,DUF4070,Radical_SAM
k59_194756_1	1166018.FAES_1893	7.75e-09	55.8	COG0818@1|root,COG0818@2|Bacteria,4NQ39@976|Bacteroidetes,47QV2@768503|Cytophagia	976|Bacteroidetes	M	PFAM diacylglycerol kinase	dgkA	-	2.7.1.107,2.7.1.66	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	-	R02240,R05626	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	DAGK_prokar
k59_81732_1	330214.NIDE2797	4.32e-138	395.0	COG1073@1|root,COG1073@2|Bacteria	2|Bacteria	S	thiolester hydrolase activity	-	-	-	ko:K06889,ko:K19296	-	-	-	-	ko00000	-	-	-	Hydrolase_4
k59_127272_1	1121405.dsmv_1717	3.09e-08	55.5	COG0618@1|root,COG0618@2|Bacteria,1N0JS@1224|Proteobacteria,42P1S@68525|delta/epsilon subdivisions,2WJV0@28221|Deltaproteobacteria,2MI7M@213118|Desulfobacterales	28221|Deltaproteobacteria	S	PFAM phosphoesterase RecJ domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DHH,DHHA1
k59_127272_2	1121405.dsmv_1718	6.31e-48	161.0	COG1234@1|root,COG1234@2|Bacteria,1PE64@1224|Proteobacteria,42RZR@68525|delta/epsilon subdivisions,2WMCC@28221|Deltaproteobacteria,2MIZZ@213118|Desulfobacterales	28221|Deltaproteobacteria	S	beta-lactamase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
k59_240479_1	290315.Clim_0637	1.43e-22	96.7	COG0671@1|root,COG0671@2|Bacteria,1FF3H@1090|Chlorobi	1090|Chlorobi	I	PFAM phosphoesterase, PA-phosphatase related	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
k59_194775_1	717772.THIAE_02760	5.82e-08	61.6	COG0642@1|root,COG5002@1|root,COG0642@2|Bacteria,COG2205@2|Bacteria,COG5002@2|Bacteria,1NRP8@1224|Proteobacteria,1SKTW@1236|Gammaproteobacteria,460AD@72273|Thiotrichales	72273|Thiotrichales	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	2.7.13.3	ko:K07646	ko02020,map02020	M00454	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	7TMR-DISMED2,7TMR-DISM_7TM,CBS,GAF_2,HATPase_c,HisKA,Hpt,MHYT,PAS,PAS_3,Response_reg
k59_59224_1	1232410.KI421426_gene1408	7.77e-17	76.6	COG0242@1|root,COG0242@2|Bacteria,1RA2P@1224|Proteobacteria,42RFN@68525|delta/epsilon subdivisions,2WP25@28221|Deltaproteobacteria,43SIF@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Polypeptide deformylase	def	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
k59_217914_1	335543.Sfum_1274	1.4e-10	61.2	COG0243@1|root,COG3383@1|root,COG0243@2|Bacteria,COG3383@2|Bacteria,1MW3N@1224|Proteobacteria,43BJY@68525|delta/epsilon subdivisions,2WIWD@28221|Deltaproteobacteria,2MRGG@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	TIGRFAM formate dehydrogenase, alpha subunit	fdnG-2	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding,TAT_signal
k59_217914_2	1265505.ATUG01000003_gene348	3.91e-83	251.0	COG0437@1|root,COG0437@2|Bacteria,1MU1B@1224|Proteobacteria,42R3B@68525|delta/epsilon subdivisions,2WN0N@28221|Deltaproteobacteria,2MK24@213118|Desulfobacterales	28221|Deltaproteobacteria	C	4Fe-4S dicluster domain	-	-	-	ko:K00124	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001	-	-	-	Fer4_11
k59_20596_1	335543.Sfum_0365	1.64e-58	197.0	COG2821@1|root,COG2821@2|Bacteria,1MXD4@1224|Proteobacteria,42P7C@68525|delta/epsilon subdivisions,2WKKF@28221|Deltaproteobacteria,2MR2J@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	MltA specific insert domain	-	-	-	ko:K08304	-	-	-	-	ko00000,ko01000,ko01011	-	GH102	-	3D,MltA
k59_164611_1	768706.Desor_2746	6.12e-81	249.0	COG0384@1|root,COG0384@2|Bacteria,1TRAF@1239|Firmicutes,25D2F@186801|Clostridia,2636J@186807|Peptococcaceae	186801|Clostridia	S	Phenazine biosynthesis-like protein	-	-	5.3.3.17	ko:K06998	ko00405,ko01130,ko02024,map00405,map01130,map02024	M00835	-	-	ko00000,ko00001,ko00002,ko01000	-	-	-	PhzC-PhzF
k59_164611_2	926560.KE387023_gene2058	1.48e-09	58.9	COG2020@1|root,COG2020@2|Bacteria	2|Bacteria	O	methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
k59_188205_1	1123371.ATXH01000029_gene32	1.23e-21	98.6	COG1538@1|root,COG1538@2|Bacteria,2GGVV@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	M	Outer membrane efflux protein	-	-	-	ko:K18139	ko01501,ko02024,map01501,map02024	M00642,M00643,M00647,M00718,M00768,M00822	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	1.B.17,2.A.6.2	-	-	OEP
k59_20605_1	1121405.dsmv_0621	3.23e-87	263.0	COG1028@1|root,COG1028@2|Bacteria,1R7KW@1224|Proteobacteria,42NF5@68525|delta/epsilon subdivisions,2WM4D@28221|Deltaproteobacteria,2MIF5@213118|Desulfobacterales	28221|Deltaproteobacteria	IQ	PFAM short-chain dehydrogenase reductase SDR	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
k59_134989_1	324925.Ppha_2544	1.06e-57	184.0	COG3335@1|root,COG3335@2|Bacteria	2|Bacteria	L	DDE superfamily endonuclease	-	-	-	ko:K07494	-	-	-	-	ko00000	-	-	-	DDE_3
k59_59229_1	1034347.CAHJ01000011_gene2274	9.56e-20	92.8	COG0006@1|root,COG0006@2|Bacteria,1TQ44@1239|Firmicutes,4HAT7@91061|Bacilli,1ZB4P@1386|Bacillus	91061|Bacilli	E	COG0006 Xaa-Pro aminopeptidase	-	-	3.4.11.9,3.4.13.9	ko:K01262,ko:K01271	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Creatinase_N,Peptidase_M24
k59_188209_1	56780.SYN_00956	4.73e-28	112.0	COG1108@1|root,COG1108@2|Bacteria,1MVC2@1224|Proteobacteria,42MYM@68525|delta/epsilon subdivisions,2WJAM@28221|Deltaproteobacteria,2MRBY@213462|Syntrophobacterales	28221|Deltaproteobacteria	P	ABC 3 transport family	-	-	-	ko:K09816	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ABC-3
k59_112076_1	335543.Sfum_3096	4e-59	203.0	COG0497@1|root,COG0497@2|Bacteria,1MUNP@1224|Proteobacteria,42N50@68525|delta/epsilon subdivisions,2WJ23@28221|Deltaproteobacteria,2MQA0@213462|Syntrophobacterales	28221|Deltaproteobacteria	L	May be involved in recombinational repair of damaged DNA	recN	-	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,SMC_N
k59_217915_1	1121405.dsmv_2761	2.3e-71	231.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,2MI1N@213118|Desulfobacterales	28221|Deltaproteobacteria	T	sigma-54 factor interaction domain-containing protein	pilR	-	-	ko:K02667	ko02020,map02020	M00501	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	HTH_8,Response_reg,Sigma54_activat
k59_217916_1	96561.Dole_2251	1.23e-123	361.0	COG0437@1|root,COG0437@2|Bacteria,1MU1B@1224|Proteobacteria,42M97@68525|delta/epsilon subdivisions,2WJB4@28221|Deltaproteobacteria,2MJB7@213118|Desulfobacterales	28221|Deltaproteobacteria	C	4Fe-4S dicluster domain	hmcB	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Fer4_11,Fer4_4,Fer4_7
k59_211315_1	1265505.ATUG01000002_gene1613	2.98e-106	332.0	COG2204@1|root,COG3829@1|root,COG2204@2|Bacteria,COG3829@2|Bacteria,1MU0N@1224|Proteobacteria,43CWU@68525|delta/epsilon subdivisions	1224|Proteobacteria	T	Bacterial regulatory protein, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
k59_28444_1	56780.SYN_01299	2.71e-36	135.0	COG0077@1|root,COG1605@1|root,COG0077@2|Bacteria,COG1605@2|Bacteria,1MU60@1224|Proteobacteria,42MGN@68525|delta/epsilon subdivisions,2WJET@28221|Deltaproteobacteria,2MR0Y@213462|Syntrophobacterales	28221|Deltaproteobacteria	E	Chorismate mutase type II	pheA	-	4.2.1.51,5.4.99.5	ko:K04518,ko:K14170	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R00691,R01373,R01715	RC00360,RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,CM_2,PDT
k59_127746_1	335543.Sfum_1464	4.36e-46	170.0	COG2202@1|root,COG3829@1|root,COG2202@2|Bacteria,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,42MEA@68525|delta/epsilon subdivisions,2WIW6@28221|Deltaproteobacteria,2MR33@213462|Syntrophobacterales	28221|Deltaproteobacteria	KT	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HTH_8,PAS_3,PAS_4,Sigma54_activat
k59_195249_1	439235.Dalk_2357	1.62e-66	213.0	COG1271@1|root,COG1271@2|Bacteria,1MV60@1224|Proteobacteria,42MB8@68525|delta/epsilon subdivisions,2WIW7@28221|Deltaproteobacteria,2MID8@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM cytochrome bd ubiquinol oxidase subunit I	cydA	-	1.10.3.14	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	Cyt_bd_oxida_I
k59_36802_1	1121405.dsmv_3752	2.1e-104	309.0	COG0016@1|root,COG0016@2|Bacteria,1MVD7@1224|Proteobacteria,42MB0@68525|delta/epsilon subdivisions,2WJ42@28221|Deltaproteobacteria,2MI3B@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily	pheS	GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iAF987.Gmet_1415	Phe_tRNA-synt_N,tRNA-synt_2d
k59_195250_1	909663.KI867150_gene213	2.1e-50	179.0	COG0457@1|root,COG0457@2|Bacteria,1NNJ6@1224|Proteobacteria,42PBD@68525|delta/epsilon subdivisions,2WKWJ@28221|Deltaproteobacteria,2MRCI@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	PFAM Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2,TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8
k59_165073_1	243231.GSU2064	5.61e-37	139.0	COG0497@1|root,COG0497@2|Bacteria,1MUNP@1224|Proteobacteria,42N50@68525|delta/epsilon subdivisions,2WJ23@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	May be involved in recombinational repair of damaged DNA	recN	-	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,SMC_N
k59_119656_1	330214.NIDE2454	2.27e-83	262.0	COG0114@1|root,COG0114@2|Bacteria,3J0FU@40117|Nitrospirae	40117|Nitrospirae	C	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate	fumC	-	4.2.1.2	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	M00009,M00011,M00173,M00376	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	FumaraseC_C,Lyase_1
k59_204780_1	1121396.KB893013_gene3705	2.02e-29	124.0	COG2844@1|root,COG2844@2|Bacteria,1MV54@1224|Proteobacteria,42MN5@68525|delta/epsilon subdivisions,2WINN@28221|Deltaproteobacteria,2MI1W@213118|Desulfobacterales	28221|Deltaproteobacteria	O	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen	glnD	-	2.7.7.59	ko:K00990	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	-	-	-	ACT,DUF294,GlnD_UR_UTase,GlnE,HD,NTP_transf_2
k59_212342_1	1313304.CALK_1953	9.65e-97	285.0	COG1592@1|root,COG1592@2|Bacteria	2|Bacteria	C	Rubrerythrin	rbr	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
k59_212342_2	1232437.KL661989_gene464	7.21e-18	75.9	COG1141@1|root,COG1141@2|Bacteria,1NEIN@1224|Proteobacteria,42V6F@68525|delta/epsilon subdivisions,2WR6R@28221|Deltaproteobacteria,2MKY6@213118|Desulfobacterales	28221|Deltaproteobacteria	C	4Fe-4S single cluster domain	-	-	-	ko:K05337	-	-	-	-	ko00000	-	-	-	Fer4_13
k59_166859_2	1232437.KL662031_gene2579	7.21e-60	206.0	COG0493@1|root,COG1148@1|root,COG0493@2|Bacteria,COG1148@2|Bacteria,1QUM4@1224|Proteobacteria,42MPP@68525|delta/epsilon subdivisions,2WJ3U@28221|Deltaproteobacteria,2MIA4@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_20,Pyr_redox_2
k59_144134_1	1121405.dsmv_1974	1.82e-141	435.0	COG0674@1|root,COG1013@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,1MVM0@1224|Proteobacteria,42MZ0@68525|delta/epsilon subdivisions,2WJ96@28221|Deltaproteobacteria,2MHRJ@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	poR	-	1.2.7.1	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00173,M00307	R01196,R10866	RC00004,RC02742	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	EKR,Fer4_16,PFOR_II,POR,POR_N,TPP_enzyme_C
k59_45593_1	439235.Dalk_1905	2.26e-52	166.0	COG0093@1|root,COG0093@2|Bacteria,1RCWZ@1224|Proteobacteria,42RHR@68525|delta/epsilon subdivisions,2WNEK@28221|Deltaproteobacteria,2MJSK@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome	rplN	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904	-	ko:K02874	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L14
k59_45593_2	96561.Dole_0719	4.57e-32	114.0	COG0198@1|root,COG0198@2|Bacteria,1MZQD@1224|Proteobacteria,42TGC@68525|delta/epsilon subdivisions,2WQ2G@28221|Deltaproteobacteria,2MKGD@213118|Desulfobacterales	28221|Deltaproteobacteria	J	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit	rplX	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02895	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KOW,ribosomal_L24
k59_219980_1	1286171.EAL2_c16130	4.19e-11	65.5	COG0589@1|root,COG0589@2|Bacteria,1VZCK@1239|Firmicutes,253YG@186801|Clostridia,25Z3J@186806|Eubacteriaceae	2|Bacteria	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
k59_60780_1	1125863.JAFN01000001_gene3080	2.37e-105	329.0	COG4206@1|root,COG4206@2|Bacteria,1MW63@1224|Proteobacteria,42P5F@68525|delta/epsilon subdivisions,2WM2S@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	TonB dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
k59_68363_1	1232410.KI421412_gene284	3.95e-25	108.0	COG0457@1|root,COG0457@2|Bacteria,1NFQW@1224|Proteobacteria,42MT2@68525|delta/epsilon subdivisions,2WKWA@28221|Deltaproteobacteria,43TXB@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	PFAM Tetratricopeptide TPR_1 repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_2,TPR_4,TPR_8
k59_235114_1	1089551.KE386572_gene2269	3.6e-67	217.0	COG0438@1|root,COG0438@2|Bacteria,1PHA6@1224|Proteobacteria,2V852@28211|Alphaproteobacteria,4BSY5@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	M	Glycosyl transferase 4-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_4
k59_83512_1	756272.Plabr_3829	1.29e-24	97.4	COG0537@1|root,COG0537@2|Bacteria,2IZTG@203682|Planctomycetes	203682|Planctomycetes	FG	COGs COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolase	-	-	2.7.7.53	ko:K19710	ko00230,map00230	-	R00126,R01618	RC00002,RC02753,RC02795	ko00000,ko00001,ko01000	-	-	-	HIT
k59_83512_2	509191.AEDB02000093_gene3425	0.000961	40.8	COG2122@1|root,COG2122@2|Bacteria,1TQ6A@1239|Firmicutes,249KT@186801|Clostridia,3WNIH@541000|Ruminococcaceae	186801|Clostridia	S	PFAM ApbE family	-	-	-	ko:K09740	-	-	-	-	ko00000	-	-	-	-
k59_151744_1	1121405.dsmv_2776	7.76e-21	95.5	2CFWZ@1|root,32ZKU@2|Bacteria,1NDUW@1224|Proteobacteria,42W37@68525|delta/epsilon subdivisions,2WRCI@28221|Deltaproteobacteria,2MKYY@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	ko:K08086	-	-	-	-	ko00000	-	-	-	-
k59_159303_1	909663.KI867150_gene857	5.81e-94	284.0	COG1063@1|root,COG1063@2|Bacteria,1QVAK@1224|Proteobacteria,43BPR@68525|delta/epsilon subdivisions,2X70Z@28221|Deltaproteobacteria,2MR6P@213462|Syntrophobacterales	28221|Deltaproteobacteria	E	Alcohol dehydrogenase GroES-like domain	-	-	1.1.1.368	ko:K07538	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00541	R05581	RC00850	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N
k59_45600_1	587753.EY04_18240	1.11e-29	120.0	COG1716@1|root,COG3456@1|root,COG1716@2|Bacteria,COG3456@2|Bacteria,1R3R7@1224|Proteobacteria,1S0GX@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Type VI secretion	fha1	-	-	ko:K07169,ko:K11894,ko:K11913	ko02025,ko03070,map02025,map03070	-	-	-	ko00000,ko00001,ko02044	3.A.23.1	-	-	FHA
k59_15267_1	879212.DespoDRAFT_01929	0.000333	43.5	COG0471@1|root,COG0471@2|Bacteria,1MU0K@1224|Proteobacteria,42MR7@68525|delta/epsilon subdivisions,2WIKA@28221|Deltaproteobacteria,2MIU8@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Citrate transporter	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS,Na_sulph_symp,TrkA_C
k59_15267_2	1121405.dsmv_2915	5.21e-07	51.6	COG4191@1|root,COG4191@2|Bacteria,1MY5P@1224|Proteobacteria,42MTA@68525|delta/epsilon subdivisions,2WJ9Q@28221|Deltaproteobacteria,2MIRX@213118|Desulfobacterales	28221|Deltaproteobacteria	T	PFAM ATP-binding region ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	4HB_MCP_1,CHASE3,HAMP,HATPase_c,HisKA
k59_83524_1	177437.HRM2_01210	4.92e-77	236.0	COG1280@1|root,COG1280@2|Bacteria,1MWA1@1224|Proteobacteria,42QQY@68525|delta/epsilon subdivisions,2WN57@28221|Deltaproteobacteria,2MJGS@213118|Desulfobacterales	28221|Deltaproteobacteria	E	LysE type translocator	-	-	-	-	-	-	-	-	-	-	-	-	LysE
k59_22841_1	335543.Sfum_2611	2.08e-46	152.0	COG1734@1|root,COG1734@2|Bacteria,1RD08@1224|Proteobacteria,42RVK@68525|delta/epsilon subdivisions,2WNNA@28221|Deltaproteobacteria,2MRZS@213462|Syntrophobacterales	28221|Deltaproteobacteria	K	PFAM zinc finger, DksA TraR C4-type	dksA	-	-	ko:K06204	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000,ko03009,ko03021	-	-	-	zf-dskA_traR
k59_22841_2	391165.GbCGDNIH1_0818	1.28e-61	194.0	COG0315@1|root,COG0315@2|Bacteria,1RCYZ@1224|Proteobacteria,2U747@28211|Alphaproteobacteria,2JS81@204441|Rhodospirillales	204441|Rhodospirillales	H	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)	moaC	-	4.6.1.17	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R11372	RC03425	ko00000,ko00001,ko01000	-	-	-	MoaC
k59_197227_1	395493.BegalDRAFT_1263	1.06e-71	229.0	COG5316@1|root,COG5316@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4139
k59_15272_1	411464.DESPIG_01302	2.45e-24	103.0	COG1403@1|root,COG1403@2|Bacteria,1QUKJ@1224|Proteobacteria,433DX@68525|delta/epsilon subdivisions,2X6YA@28221|Deltaproteobacteria,2MD1P@213115|Desulfovibrionales	28221|Deltaproteobacteria	V	HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_98688_1	1161401.ASJA01000027_gene52	1.09e-29	118.0	COG2067@1|root,COG2067@2|Bacteria,1MUU4@1224|Proteobacteria,2TS9S@28211|Alphaproteobacteria,43XP7@69657|Hyphomonadaceae	28211|Alphaproteobacteria	I	Outer membrane protein transport protein (OMPP1/FadL/TodX)	-	-	-	ko:K06076	-	-	-	-	ko00000,ko02000	1.B.9	-	-	Toluene_X
k59_227560_1	1047013.AQSP01000128_gene418	7.77e-34	129.0	COG0739@1|root,COG0739@2|Bacteria	2|Bacteria	M	heme binding	-	-	3.4.24.75	ko:K08259	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M23
k59_53195_1	1121405.dsmv_3606	7.67e-21	85.9	2E3F6@1|root,32YE2@2|Bacteria,1NDBB@1224|Proteobacteria,42WNV@68525|delta/epsilon subdivisions,2WRV2@28221|Deltaproteobacteria,2MKYS@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_159325_1	243231.GSU2226	1.93e-48	165.0	COG1159@1|root,COG1159@2|Bacteria,1MUKT@1224|Proteobacteria,42MUR@68525|delta/epsilon subdivisions,2WJC8@28221|Deltaproteobacteria,43TV2@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism	era	-	-	ko:K03595	-	-	-	-	ko00000,ko03009,ko03029	-	-	-	KH_2,MMR_HSR1
k59_30456_1	1304883.KI912532_gene3208	1.16e-07	51.6	COG1522@1|root,COG1522@2|Bacteria,1RIKY@1224|Proteobacteria,2VSBM@28216|Betaproteobacteria,2KWF6@206389|Rhodocyclales	206389|Rhodocyclales	K	overlaps another CDS with the same product name	nirG	-	-	-	-	-	-	-	-	-	-	-	HTH_AsnC-type
k59_30456_2	933262.AXAM01000055_gene1249	8.82e-92	278.0	COG0182@1|root,COG0182@2|Bacteria,1MUPM@1224|Proteobacteria,42MJ2@68525|delta/epsilon subdivisions,2WJQB@28221|Deltaproteobacteria,2MITS@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)	mtnA	-	5.3.1.23	ko:K08963	ko00270,ko01100,map00270,map01100	M00034	R04420	RC01151	ko00000,ko00001,ko00002,ko01000	-	-	-	IF-2B
k59_45623_1	667014.Thein_0606	2.95e-19	89.0	COG1190@1|root,COG1190@2|Bacteria,2GGTQ@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	J	Belongs to the class-II aminoacyl-tRNA synthetase family	lysS	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
k59_45623_2	574966.KB898647_gene2332	9.24e-14	73.9	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,1RY0I@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
k59_98700_1	933262.AXAM01000079_gene2201	1.65e-127	401.0	COG0086@1|root,COG0086@2|Bacteria,1MU3M@1224|Proteobacteria,42NAW@68525|delta/epsilon subdivisions,2WISU@28221|Deltaproteobacteria,2MIYJ@213118|Desulfobacterales	28221|Deltaproteobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	-	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
k59_98702_1	526222.Desal_3767	4.11e-58	203.0	COG1205@1|root,COG1205@2|Bacteria,1QU0I@1224|Proteobacteria,42M4R@68525|delta/epsilon subdivisions,2WK1V@28221|Deltaproteobacteria,2M8EC@213115|Desulfovibrionales	28221|Deltaproteobacteria	L	DEAD DEAH box helicase domain protein	yprA	-	-	ko:K06877	-	-	-	-	ko00000	-	-	-	DEAD,DUF1998,Helicase_C,RNase_H_2
k59_204814_1	439235.Dalk_4634	1.18e-14	74.7	COG4942@1|root,COG4942@2|Bacteria,1MY3E@1224|Proteobacteria,42N32@68525|delta/epsilon subdivisions,2WKBN@28221|Deltaproteobacteria,2MI0S@213118|Desulfobacterales	28221|Deltaproteobacteria	D	PFAM peptidase	-	-	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M23,SH3_3
k59_45626_2	1121396.KB893112_gene1966	4.21e-09	58.9	COG4967@1|root,COG4967@2|Bacteria,1PSVQ@1224|Proteobacteria,437CX@68525|delta/epsilon subdivisions,2X2IS@28221|Deltaproteobacteria,2MM7T@213118|Desulfobacterales	28221|Deltaproteobacteria	NU	Prokaryotic N-terminal methylation motif	-	-	-	ko:K02458	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl
k59_91082_1	1121403.AUCV01000003_gene1782	4.19e-08	55.1	COG1502@1|root,COG1502@2|Bacteria,1MWUW@1224|Proteobacteria,42PV9@68525|delta/epsilon subdivisions,2WKF2@28221|Deltaproteobacteria,2MJW6@213118|Desulfobacterales	28221|Deltaproteobacteria	I	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol	clsA	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2,PLDc_N
k59_220013_1	1187851.A33M_1621	1.78e-41	149.0	COG1063@1|root,COG1063@2|Bacteria,1MV9A@1224|Proteobacteria,2TSWA@28211|Alphaproteobacteria,3FEDA@34008|Rhodovulum	28211|Alphaproteobacteria	E	Alcohol dehydrogenase GroES-like domain	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
k59_30464_1	880072.Desac_0718	1.69e-72	233.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WJ88@28221|Deltaproteobacteria,2MRG9@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	two component, sigma54 specific, transcriptional regulator, Fis family	ntrX	-	-	ko:K13599	ko02020,map02020	M00498	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
k59_60808_1	1134413.ANNK01000127_gene2497	6.12e-09	62.8	COG0673@1|root,COG0673@2|Bacteria,1TQSS@1239|Firmicutes,4HCIG@91061|Bacilli,1ZBUF@1386|Bacillus	91061|Bacilli	S	Oxidoreductase	yulF	GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016616,GO:0055114,GO:0102497	-	ko:K22230	ko00562,ko01120,map00562,map01120	-	R09954	RC00182	ko00000,ko00001,ko01000	-	-	-	GFO_IDH_MocA
k59_113847_1	96561.Dole_0472	4.24e-58	190.0	COG0216@1|root,COG0216@2|Bacteria,1MV28@1224|Proteobacteria,42NA3@68525|delta/epsilon subdivisions,2WIQU@28221|Deltaproteobacteria,2MHQM@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
k59_113847_2	879310.HMPREF9162_2395	1.18e-29	114.0	COG2890@1|root,COG2890@2|Bacteria,1TSMA@1239|Firmicutes,4H2VA@909932|Negativicutes	909932|Negativicutes	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif	prmC	-	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS,Methyltransf_31
k59_174489_1	1121406.JAEX01000005_gene3049	3.93e-60	197.0	COG0765@1|root,COG0765@2|Bacteria,1MX3E@1224|Proteobacteria,42N9B@68525|delta/epsilon subdivisions,2WIYW@28221|Deltaproteobacteria,2M9VH@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	TIGRFAM polar amino acid ABC transporter, inner membrane subunit	-	-	-	ko:K02029,ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	BPD_transp_1,SBP_bac_3
k59_60809_1	667014.Thein_0302	4.23e-38	140.0	COG0119@1|root,COG0119@2|Bacteria,2GGR2@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	E	Belongs to the alpha-IPM synthase homocitrate synthase family	-	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
k59_106300_1	1304872.JAGC01000009_gene975	2.35e-50	181.0	COG2984@1|root,COG3852@1|root,COG4191@1|root,COG2984@2|Bacteria,COG3852@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MC4@68525|delta/epsilon subdivisions,2WIZU@28221|Deltaproteobacteria,2MHBV@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	ABC_sub_bind,HATPase_c,HisKA,PAS_4,PAS_9,Response_reg
k59_159344_1	644282.Deba_2974	7.08e-35	129.0	COG1028@1|root,COG1028@2|Bacteria,1MURZ@1224|Proteobacteria,42S8U@68525|delta/epsilon subdivisions,2WND3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
k59_235173_1	933262.AXAM01000013_gene1324	1.75e-109	342.0	COG0532@1|root,COG0532@2|Bacteria,1MV26@1224|Proteobacteria,42M5Q@68525|delta/epsilon subdivisions,2WIIX@28221|Deltaproteobacteria,2MIGT@213118|Desulfobacterales	28221|Deltaproteobacteria	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,IF-2,IF2_N
k59_121464_1	439235.Dalk_2961	2.66e-48	166.0	COG1639@1|root,COG1639@2|Bacteria,1RBFE@1224|Proteobacteria,42QRK@68525|delta/epsilon subdivisions,2WMYG@28221|Deltaproteobacteria,2MJHI@213118|Desulfobacterales	28221|Deltaproteobacteria	T	HDOD domain	-	-	-	-	-	-	-	-	-	-	-	-	HDOD,zinc_ribbon_4
k59_144174_1	335543.Sfum_2006	6.34e-31	120.0	COG0642@1|root,COG2205@2|Bacteria,1MW8M@1224|Proteobacteria,42QF7@68525|delta/epsilon subdivisions,2WJAU@28221|Deltaproteobacteria,2MQKF@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	2.7.13.3	ko:K07644	ko02020,map02020	M00452,M00745	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS_9,Response_reg
k59_144174_2	335543.Sfum_2007	2.3e-41	141.0	COG0745@1|root,COG0745@2|Bacteria,1MU67@1224|Proteobacteria,42N90@68525|delta/epsilon subdivisions,2WJUU@28221|Deltaproteobacteria,2MRIT@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
k59_153_1	1121405.dsmv_2306	5.68e-128	382.0	COG0465@1|root,COG0465@2|Bacteria,1MU6J@1224|Proteobacteria,42M4Z@68525|delta/epsilon subdivisions,2WJZ3@28221|Deltaproteobacteria,2MN0D@213118|Desulfobacterales	28221|Deltaproteobacteria	O	Peptidase family M41	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
k59_45639_1	1121439.dsat_0263	1.86e-56	186.0	COG2078@1|root,COG2078@2|Bacteria,1RJP4@1224|Proteobacteria,42SBG@68525|delta/epsilon subdivisions,2WP66@28221|Deltaproteobacteria,2MB3T@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	PFAM AMMECR1 domain protein	-	-	-	ko:K09141	-	-	-	-	ko00000	-	-	-	AMMECR1
k59_15288_1	1121405.dsmv_0753	6.57e-96	290.0	COG0683@1|root,COG0683@2|Bacteria,1MWJ1@1224|Proteobacteria,42PEN@68525|delta/epsilon subdivisions,2WJ9F@28221|Deltaproteobacteria,2MIQU@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Receptor family ligand binding region	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
k59_212368_1	1121918.ARWE01000001_gene1672	4.04e-28	103.0	COG0776@1|root,COG0776@2|Bacteria,1MZ7M@1224|Proteobacteria,42TVD@68525|delta/epsilon subdivisions,2WQPX@28221|Deltaproteobacteria,43SP9@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	Belongs to the bacterial histone-like protein family	ihfB	-	-	ko:K05788	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
k59_189674_1	1122947.FR7_3078	1.88e-36	134.0	COG3434@1|root,COG3434@2|Bacteria,1TPWC@1239|Firmicutes,4H2CH@909932|Negativicutes	909932|Negativicutes	T	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	EAL,HDOD
k59_189674_2	1121396.KB892903_gene4240	1.32e-22	93.6	COG0299@1|root,COG0299@2|Bacteria,1MWN1@1224|Proteobacteria,42R30@68525|delta/epsilon subdivisions,2WJT0@28221|Deltaproteobacteria,2MJ3P@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate	purN	-	2.1.2.2	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	Formyl_trans_N
k59_212374_1	335543.Sfum_2526	2.43e-33	124.0	COG1163@1|root,COG1163@2|Bacteria,1RFPD@1224|Proteobacteria,42ZF3@68525|delta/epsilon subdivisions,2WUZY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	TGS domain	-	-	-	ko:K06944	-	-	-	-	ko00000	-	-	-	MMR_HSR1,TGS
k59_129051_1	1121405.dsmv_3391	5.84e-88	278.0	COG0493@1|root,COG2878@1|root,COG0493@2|Bacteria,COG2878@2|Bacteria,1MU2H@1224|Proteobacteria,42M6X@68525|delta/epsilon subdivisions,2WIVF@28221|Deltaproteobacteria,2MIVJ@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Fe-S cluster domain protein	-	-	-	-	-	-	-	-	-	-	-	-	FeS,Fer4,Fer4_20,Fer4_7,Pyr_redox_2,Pyr_redox_3
k59_129057_1	335543.Sfum_2756	6.11e-13	73.9	COG0707@1|root,COG1413@1|root,COG0707@2|Bacteria,COG1413@2|Bacteria,1MVIB@1224|Proteobacteria,42ME1@68525|delta/epsilon subdivisions,2WJNY@28221|Deltaproteobacteria,2MRPC@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
k59_121476_1	96561.Dole_0946	9.89e-67	206.0	COG0102@1|root,COG0102@2|Bacteria,1RA11@1224|Proteobacteria,42SD5@68525|delta/epsilon subdivisions,2WP5M@28221|Deltaproteobacteria,2MKE6@213118|Desulfobacterales	28221|Deltaproteobacteria	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rplM	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
k59_121476_2	335543.Sfum_1668	3.14e-59	186.0	COG0103@1|root,COG0103@2|Bacteria,1RD4A@1224|Proteobacteria,42SVI@68525|delta/epsilon subdivisions,2WP7T@28221|Deltaproteobacteria,2MQKD@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	Belongs to the universal ribosomal protein uS9 family	rpsI	-	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
k59_204836_1	1191523.MROS_0432	2.01e-147	449.0	COG0653@1|root,COG0653@2|Bacteria	2|Bacteria	U	protein targeting	secA	GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	Helicase_C,SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
k59_212382_1	1394178.AWOO02000071_gene396	5.3e-69	224.0	COG1653@1|root,COG1653@2|Bacteria,2IDWS@201174|Actinobacteria	201174|Actinobacteria	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1,SBP_bac_8
k59_98727_1	933262.AXAM01000048_gene2601	1.79e-50	181.0	COG2937@1|root,COG2937@2|Bacteria,1MWZ6@1224|Proteobacteria,42MN4@68525|delta/epsilon subdivisions,2WJJ5@28221|Deltaproteobacteria,2MHRG@213118|Desulfobacterales	28221|Deltaproteobacteria	I	Belongs to the GPAT DAPAT family	plsB	-	2.3.1.15	ko:K00631	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
k59_75993_2	1121405.dsmv_1161	2.6e-115	346.0	COG0215@1|root,COG0215@2|Bacteria,1MV8H@1224|Proteobacteria,42M04@68525|delta/epsilon subdivisions,2WJJD@28221|Deltaproteobacteria,2MIN7@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e,tRNA-synt_1g
k59_227587_1	880072.Desac_2077	1.41e-69	216.0	COG0491@1|root,COG0491@2|Bacteria,1MUT2@1224|Proteobacteria,42MVA@68525|delta/epsilon subdivisions,2WKBW@28221|Deltaproteobacteria,2MS92@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
k59_235550_1	404589.Anae109_3070	1.27e-94	305.0	COG0296@1|root,COG3281@1|root,COG0296@2|Bacteria,COG3281@2|Bacteria,1QTVN@1224|Proteobacteria,42NYT@68525|delta/epsilon subdivisions,2WIM3@28221|Deltaproteobacteria,2Z34A@29|Myxococcales	28221|Deltaproteobacteria	G	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position	glgB	-	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_48
k59_8121_1	202955.BBND01000005_gene270	1.64e-08	60.1	COG3385@1|root,COG3385@2|Bacteria,1R8M9@1224|Proteobacteria,1S1W5@1236|Gammaproteobacteria,3NMWG@468|Moraxellaceae	1236|Gammaproteobacteria	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
k59_182423_1	907348.TresaDRAFT_1651	2.1e-17	79.3	COG0235@1|root,COG0235@2|Bacteria,2J6M1@203691|Spirochaetes	203691|Spirochaetes	G	PFAM Class II Aldolase and Adducin N-terminal domain	-	-	5.1.3.4	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	M00550	R05850	RC01479	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldolase_II
k59_182423_2	869213.JCM21142_93730	4.38e-45	160.0	COG1069@1|root,COG1069@2|Bacteria,4NEFQ@976|Bacteroidetes,47KBR@768503|Cytophagia	976|Bacteroidetes	G	Belongs to the ribulokinase family	araB	-	2.7.1.16	ko:K00853	ko00040,ko01100,map00040,map01100	-	R01526,R02439	RC00002,RC00538	ko00000,ko00001,ko01000	-	-	-	FGGY_C,FGGY_N
k59_173261_2	1485545.JQLW01000008_gene1984	2.32e-08	62.4	COG0615@1|root,COG0615@2|Bacteria,1N9T6@1224|Proteobacteria	1224|Proteobacteria	IM	Sulfotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_3
k59_43882_1	335543.Sfum_0007	6.42e-104	316.0	COG0034@1|root,COG0034@2|Bacteria,1MU0V@1224|Proteobacteria,42MDB@68525|delta/epsilon subdivisions,2WITV@28221|Deltaproteobacteria,2MQZD@213462|Syntrophobacterales	28221|Deltaproteobacteria	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_6,GATase_7,Pribosyltran
k59_226120_1	999413.HMPREF1094_03446	5.85e-20	94.4	COG1961@1|root,COG1961@2|Bacteria,1TPUG@1239|Firmicutes,3VR4I@526524|Erysipelotrichia	526524|Erysipelotrichia	L	Resolvase, N terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase
k59_211556_1	706587.Desti_2925	1.79e-65	209.0	COG1235@1|root,COG1235@2|Bacteria,1MVJH@1224|Proteobacteria,42W9U@68525|delta/epsilon subdivisions,2WRHS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Beta-lactamase superfamily domain	-	-	3.1.4.55	ko:K06167	ko00440,map00440	-	R10205	RC00296	ko00000,ko00001,ko01000	-	-	-	Lactamase_B_2
k59_180433_1	1499967.BAYZ01000171_gene5615	1.1e-68	234.0	COG0392@1|root,COG2898@1|root,COG0392@2|Bacteria,COG2898@2|Bacteria	2|Bacteria	K	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms	mprF	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	2.3.2.3	ko:K07027,ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	M00726	-	-	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	2.A.1.3.37,4.D.2	-	iYO844.BG12900	DUF2156,LPG_synthase_TM
k59_241181_1	1116375.VEJY3_20801	1.49e-60	204.0	COG3547@1|root,COG3547@2|Bacteria,1NGR7@1224|Proteobacteria,1RMF9@1236|Gammaproteobacteria,1XURY@135623|Vibrionales	135623|Vibrionales	L	Transposase IS116/IS110/IS902 family	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_66749_1	1265505.ATUG01000003_gene342	1.08e-83	274.0	COG1148@1|root,COG1148@2|Bacteria,1QUM4@1224|Proteobacteria,42MPP@68525|delta/epsilon subdivisions,2WJ3U@28221|Deltaproteobacteria,2MIJ3@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM Pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Pyr_redox_2
k59_211557_1	66269.NL54_21495	0.000337	47.0	COG2968@1|root,COG2968@2|Bacteria,1RH7T@1224|Proteobacteria,1RP7T@1236|Gammaproteobacteria,3VXJB@53335|Pantoea	1236|Gammaproteobacteria	S	Protein of unknown function (DUF541)	yggE	GO:0000302,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006950,GO:0006974,GO:0006979,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009897,GO:0009986,GO:0009987,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0031233,GO:0033554,GO:0034599,GO:0034605,GO:0034614,GO:0042221,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051716,GO:0070887,GO:0071575,GO:0071944,GO:0098552,GO:1901700,GO:1901701	-	ko:K09807	-	-	-	-	ko00000	-	-	-	SIMPL
k59_51560_1	384616.Pisl_0811	1.18e-35	134.0	COG3425@1|root,arCOG01767@2157|Archaea,2XPKK@28889|Crenarchaeota	28889|Crenarchaeota	I	Belongs to the UPF0219 family	-	-	2.3.3.10	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	M00088,M00095	R01978	RC00004,RC00503	ko00000,ko00001,ko00002,ko01000	-	-	-	ACP_syn_III,ACP_syn_III_C,HMG_CoA_synt_N,Thiolase_N
k59_97425_1	411464.DESPIG_02308	2.2e-48	175.0	COG1026@1|root,COG1026@2|Bacteria,1MVDJ@1224|Proteobacteria,42MRG@68525|delta/epsilon subdivisions,2WJ5Q@28221|Deltaproteobacteria,2M9EM@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	PFAM Peptidase M16C associated	PREP	-	-	ko:K06972	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M16C_assoc,Peptidase_M16,Peptidase_M16_C
k59_165240_1	1321784.HMPREF1987_02145	9.44e-16	82.8	COG0587@1|root,COG0587@2|Bacteria,1TPYG@1239|Firmicutes,247U0@186801|Clostridia,25QW9@186804|Peptostreptococcaceae	186801|Clostridia	L	DNA polymerase	dnaE	-	2.7.7.7	ko:K02337,ko:K14162	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
k59_226128_1	1121405.dsmv_0776	1.91e-82	251.0	COG1521@1|root,COG1521@2|Bacteria,1MUYA@1224|Proteobacteria,42MVZ@68525|delta/epsilon subdivisions,2WJ3N@28221|Deltaproteobacteria,2MJ6S@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis	coaX	-	2.7.1.33	ko:K03525	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1986	Pan_kinase
k59_234393_1	643562.Daes_3209	2.93e-44	151.0	29XY6@1|root,30JQT@2|Bacteria,1PWGF@1224|Proteobacteria,4373T@68525|delta/epsilon subdivisions,2X1XZ@28221|Deltaproteobacteria,2MFU4@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Lipid A 3-O-deacylase (PagL)	-	-	-	ko:K12976	-	-	-	-	ko00000,ko01000,ko01005	-	-	-	PagL
k59_43897_1	1499967.BAYZ01000078_gene985	1.13e-148	431.0	COG1541@1|root,COG1541@2|Bacteria,2NREC@2323|unclassified Bacteria	2|Bacteria	H	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)	paaK	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C_2
k59_28639_1	694440.JOMF01000007_gene886	3.67e-70	223.0	COG1405@1|root,arCOG01981@2157|Archaea,2XT0Z@28890|Euryarchaeota,2N96C@224756|Methanomicrobia	224756|Methanomicrobia	K	Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB)	tfb	-	-	ko:K03124	ko03022,ko05169,ko05203,map03022,map05169,map05203	-	-	-	ko00000,ko00001,ko03021	-	-	-	TFIIB,TF_Zn_Ribbon
k59_143361_1	224325.AF_0676	1.02e-81	248.0	COG0563@1|root,arCOG01046@2157|Archaea,2XTRG@28890|Euryarchaeota,246UX@183980|Archaeoglobi	183980|Archaeoglobi	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK,ADK_lid
k59_112784_1	479431.Namu_4487	5.2e-24	103.0	COG3385@1|root,COG5659@1|root,COG3385@2|Bacteria,COG5659@2|Bacteria,2GIU9@201174|Actinobacteria,4ETY1@85013|Frankiales	201174|Actinobacteria	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_5
k59_5482_1	335543.Sfum_2584	4.63e-179	513.0	COG0056@1|root,COG0056@2|Bacteria,1MUG7@1224|Proteobacteria,42MVX@68525|delta/epsilon subdivisions,2WIK7@28221|Deltaproteobacteria,2MRD2@213462|Syntrophobacterales	28221|Deltaproteobacteria	F	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
k59_218549_1	706587.Desti_2931	8.29e-17	85.1	COG3383@1|root,COG3383@2|Bacteria,1QW12@1224|Proteobacteria,43BQY@68525|delta/epsilon subdivisions,2X5UH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	2Fe-2S iron-sulfur cluster binding domain	sfrA	GO:0003674,GO:0003824,GO:0003954,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016651,GO:0044237,GO:0044424,GO:0044464,GO:0045333,GO:0048037,GO:0051536,GO:0051540,GO:0055114,GO:0071944	1.17.1.10	ko:K05299	ko00680,ko00720,ko01100,ko01120,ko01200,map00680,map00720,map01100,map01120,map01200	M00377	R00134	RC02796	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_4,Fer4,Fer4_10,Fer4_7,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
k59_135842_1	1121405.dsmv_2719	2.1e-73	232.0	COG0372@1|root,COG0372@2|Bacteria,1MUKX@1224|Proteobacteria,42N8U@68525|delta/epsilon subdivisions,2WJAN@28221|Deltaproteobacteria,2MHQF@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Belongs to the citrate synthase family	citZ	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt,HTH_17
k59_165249_1	439235.Dalk_1493	4.83e-94	275.0	COG5561@1|root,COG5561@2|Bacteria,1RFC4@1224|Proteobacteria,42S7T@68525|delta/epsilon subdivisions,2WNU0@28221|Deltaproteobacteria,2MJYT@213118|Desulfobacterales	28221|Deltaproteobacteria	S	CGGC	-	-	-	-	-	-	-	-	-	-	-	-	CGGC
k59_173273_1	1121405.dsmv_3648	4.1e-74	227.0	COG0081@1|root,COG0081@2|Bacteria,1MUE6@1224|Proteobacteria,42MZP@68525|delta/epsilon subdivisions,2WJ1Z@28221|Deltaproteobacteria,2MHWH@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release	rplA	GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02863	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L1
k59_82579_1	203122.Sde_1835	4.12e-76	243.0	COG3547@1|root,COG3547@2|Bacteria,1NGR7@1224|Proteobacteria,1RMF9@1236|Gammaproteobacteria,464W8@72275|Alteromonadaceae	1236|Gammaproteobacteria	L	COG3547 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_74748_1	439235.Dalk_0904	3.19e-21	93.6	2ADFT@1|root,3135W@2|Bacteria,1MY8W@1224|Proteobacteria,42SW3@68525|delta/epsilon subdivisions,2WPYE@28221|Deltaproteobacteria,2MK86@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_188972_1	98439.AJLL01000076_gene1020	2.24e-39	151.0	COG0642@1|root,COG2202@1|root,COG2202@2|Bacteria,COG2205@2|Bacteria,1G46J@1117|Cyanobacteria,1JH02@1189|Stigonemataceae	1117|Cyanobacteria	T	Histidine kinase-like ATPases	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_9
k59_203724_1	338963.Pcar_2483	3.08e-56	177.0	COG0730@1|root,COG0730@2|Bacteria,1PD7F@1224|Proteobacteria,42TC8@68525|delta/epsilon subdivisions,2WPFJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Sulfite exporter TauE/SafE	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
k59_203724_2	1268072.PSAB_03025	2.03e-37	131.0	COG0778@1|root,COG0778@2|Bacteria,1V4ZI@1239|Firmicutes	1239|Firmicutes	C	Nitroreductase	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
k59_43906_1	879212.DespoDRAFT_02828	3.86e-125	362.0	COG1484@1|root,COG1484@2|Bacteria,1MWQX@1224|Proteobacteria,42NG2@68525|delta/epsilon subdivisions,2WK33@28221|Deltaproteobacteria,2MPZT@213118|Desulfobacterales	28221|Deltaproteobacteria	L	PFAM IstB-like ATP binding protein	-	-	-	-	-	-	-	-	-	-	-	-	IstB_IS21
k59_195449_1	207559.Dde_3715	1.72e-57	197.0	COG2204@1|root,COG4191@1|root,COG2204@2|Bacteria,COG4191@2|Bacteria,1QZPK@1224|Proteobacteria,42NQE@68525|delta/epsilon subdivisions,2WJPH@28221|Deltaproteobacteria,2M8MZ@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,PAS_4,PAS_9,Response_reg
k59_226143_2	1415775.U729_370	6.74e-61	211.0	COG2766@1|root,COG2766@2|Bacteria,1TRTW@1239|Firmicutes,248GE@186801|Clostridia,36E3Y@31979|Clostridiaceae	186801|Clostridia	T	PrkA serine	prkA	-	-	ko:K07180	-	-	-	-	ko00000	-	-	-	AAA_PrkA,PrkA
k59_5507_1	56780.SYN_00647	5.03e-46	164.0	COG1042@1|root,COG1042@2|Bacteria,1MW98@1224|Proteobacteria,42KZW@68525|delta/epsilon subdivisions,2WIQB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	CoA-binding domain protein	-	-	6.2.1.13	ko:K01905,ko:K09181,ko:K22224	ko00010,ko00620,ko00640,ko01100,ko01120,map00010,map00620,map00640,map01100,map01120	-	R00229,R00920	RC00004,RC00012,RC00014	ko00000,ko00001,ko01000,ko01004	-	-	-	ATP-grasp_5,Acetyltransf_1,CoA_binding_2,Succ_CoA_lig
k59_37509_1	566466.NOR53_724	1.95e-17	88.6	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1J5MB@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	CZB,DUF4118,EAL,GAF_2,GGDEF,PAS_3,PAS_4,PAS_9,Protoglobin
k59_165758_1	1233950.IW22_15625	1.3e-33	124.0	COG0384@1|root,COG0384@2|Bacteria,4NMWV@976|Bacteroidetes,1I4NW@117743|Flavobacteriia,3ZRD6@59732|Chryseobacterium	976|Bacteroidetes	S	Phenazine biosynthesis-like protein	-	-	5.3.3.17	ko:K06998	ko00405,ko01130,ko02024,map00405,map01130,map02024	M00835	-	-	ko00000,ko00001,ko00002,ko01000	-	-	-	PhzC-PhzF
k59_165758_2	479434.Sthe_0370	1.11e-60	194.0	2DW90@1|root,33Z49@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1706)	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_165758_3	1121920.AUAU01000005_gene976	6.08e-32	115.0	2E31H@1|root,32Y1W@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_113374_1	1054213.HMPREF9946_04597	2.45e-17	82.4	COG5394@1|root,COG5394@2|Bacteria,1RHRC@1224|Proteobacteria,2TQWQ@28211|Alphaproteobacteria,2JRP3@204441|Rhodospirillales	204441|Rhodospirillales	S	Polyhydroxyalkanoate synthesis repressor	-	-	-	-	-	-	-	-	-	-	-	-	PHB_acc,PHB_acc_N
k59_204301_1	1121405.dsmv_3000	5.65e-43	152.0	COG0674@1|root,COG0674@2|Bacteria,1R4K0@1224|Proteobacteria,42NQJ@68525|delta/epsilon subdivisions,2WJ0K@28221|Deltaproteobacteria,2MIND@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Pyruvate:ferredoxin oxidoreductase core domain II	-	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR_N
k59_204301_2	1265505.ATUG01000001_gene3465	2.83e-45	157.0	COG1013@1|root,COG1014@1|root,COG1013@2|Bacteria,COG1014@2|Bacteria,1R7US@1224|Proteobacteria,42PFT@68525|delta/epsilon subdivisions,2WMBJ@28221|Deltaproteobacteria,2MJ1Z@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Pyruvate ferredoxin/flavodoxin oxidoreductase	-	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	POR,TPP_enzyme_C
k59_128522_1	1121405.dsmv_3691	4.58e-97	295.0	COG3547@1|root,COG3547@2|Bacteria,1NP2U@1224|Proteobacteria,43A5Q@68525|delta/epsilon subdivisions,2X2AM@28221|Deltaproteobacteria,2MPDW@213118|Desulfobacterales	28221|Deltaproteobacteria	L	Transposase (IS116 IS110 IS902 family)	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_120613_1	1121918.ARWE01000001_gene3104	3.4e-54	183.0	COG0845@1|root,COG0845@2|Bacteria,1MUFW@1224|Proteobacteria,42N4G@68525|delta/epsilon subdivisions,2WJ8A@28221|Deltaproteobacteria,43TCG@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	HlyD family secretion protein	-	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	HlyD_D23
k59_204303_1	1121405.dsmv_3101	1.55e-96	294.0	COG0592@1|root,COG0592@2|Bacteria,1MVD9@1224|Proteobacteria,42NQW@68525|delta/epsilon subdivisions,2WJZM@28221|Deltaproteobacteria,2MHS9@213118|Desulfobacterales	28221|Deltaproteobacteria	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	dnaN	-	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
k59_90468_1	1045855.DSC_05160	2.19e-62	204.0	COG3039@1|root,COG3039@2|Bacteria,1R64B@1224|Proteobacteria	1224|Proteobacteria	L	Transposase domain (DUF772)	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DUF772
k59_241669_1	706587.Desti_3270	1.93e-72	246.0	COG2202@1|root,COG2203@1|root,COG2204@1|root,COG4191@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG2204@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MC4@68525|delta/epsilon subdivisions,2WIU5@28221|Deltaproteobacteria,2MQZQ@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
k59_158723_1	713586.KB900536_gene2513	3.15e-45	160.0	COG2801@1|root,COG2801@2|Bacteria,1N207@1224|Proteobacteria,1S1FB@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	COG2801 Transposase and inactivated derivatives	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_32,LZ_Tnp_IS481,rve,rve_3
k59_173810_1	768670.Calni_1741	6.22e-57	184.0	COG0279@1|root,COG0279@2|Bacteria,2GFD6@200930|Deferribacteres	200930|Deferribacteres	G	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate	gmhA	-	5.3.1.28	ko:K03271	ko00540,ko01100,map00540,map01100	M00064	R05645,R09768,R09769	RC00434	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	SIS_2
k59_173810_2	880072.Desac_1971	1.8e-14	73.9	COG1899@1|root,COG1899@2|Bacteria,1R3WQ@1224|Proteobacteria,42M57@68525|delta/epsilon subdivisions,2WJ6N@28221|Deltaproteobacteria,2MREK@213462|Syntrophobacterales	28221|Deltaproteobacteria	O	peptidyl-lysine modification to peptidyl-hypusine	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_165760_1	279383.Q5DN23_9CAUD	1.81e-67	228.0	4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses  no RNA stage,4QPBY@28883|Caudovirales,4QKKV@10699|Siphoviridae	10699|Siphoviridae	S	peptidoglycan catabolic process	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_37516_1	1232437.KL661958_gene2881	2.41e-102	315.0	COG2414@1|root,COG2414@2|Bacteria,1R5AG@1224|Proteobacteria,42NHF@68525|delta/epsilon subdivisions,2WK3Z@28221|Deltaproteobacteria,2MIT9@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Aldehyde ferredoxin oxidoreductase, N-terminal domain	bamB-1	-	1.2.7.5	ko:K03738,ko:K19515	ko00030,ko00362,ko01100,ko01120,ko01200,map00030,map00362,map01100,map01120,map01200	M00309,M00541	R08571,R10961	RC00242,RC01839	ko00000,ko00001,ko00002,ko01000	-	-	-	AFOR_C,AFOR_N
k59_195987_1	68194.JNXR01000006_gene3682	4.78e-07	52.4	COG0477@1|root,COG2814@2|Bacteria,2H2CQ@201174|Actinobacteria	201174|Actinobacteria	EGP	Major Facilitator	fsr	-	-	ko:K08223	-	-	-	-	ko00000,ko02000	2.A.1.35	-	-	MFS_1
k59_113392_1	439235.Dalk_2380	1.61e-61	192.0	COG0426@1|root,COG0426@2|Bacteria,1RKK1@1224|Proteobacteria,42RRR@68525|delta/epsilon subdivisions,2WP60@28221|Deltaproteobacteria,2MK3X@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Flavodoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	Flavodoxin_5
k59_241675_1	1366050.N234_01090	4.5e-70	225.0	COG0683@1|root,COG0683@2|Bacteria,1MWQB@1224|Proteobacteria,2WEZH@28216|Betaproteobacteria	28216|Betaproteobacteria	E	Receptor family ligand binding region	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
k59_105900_1	1265505.ATUG01000002_gene2500	9.19e-45	148.0	COG0016@1|root,COG0016@2|Bacteria,1NVRM@1224|Proteobacteria,4307G@68525|delta/epsilon subdivisions,2WVF3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_52179_1	335543.Sfum_2805	8.86e-42	149.0	COG0509@1|root,COG0509@2|Bacteria,1Q1KI@1224|Proteobacteria,437BG@68525|delta/epsilon subdivisions,2X2GI@28221|Deltaproteobacteria,2MRJR@213462|Syntrophobacterales	28221|Deltaproteobacteria	E	PFAM glycine cleavage H-protein	-	-	-	-	-	-	-	-	-	-	-	-	GCV_H
k59_165775_1	1121405.dsmv_0666	4.44e-162	466.0	COG3604@1|root,COG3604@2|Bacteria,1QTT3@1224|Proteobacteria,42Y69@68525|delta/epsilon subdivisions,2WJ5F@28221|Deltaproteobacteria,2MI66@213118|Desulfobacterales	28221|Deltaproteobacteria	KT	PFAM sigma-54 factor interaction domain-containing protein	-	-	-	ko:K02584	ko02020,map02020	-	-	-	ko00000,ko00001,ko03000	-	-	-	GAF,GAF_2,HTH_8,Sigma54_activat
k59_83066_1	177437.HRM2_28690	1.12e-05	54.7	COG2202@1|root,COG4191@1|root,COG2202@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MC4@68525|delta/epsilon subdivisions,2WIZU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_9,Response_reg
k59_6030_1	886293.Sinac_2704	3.11e-38	138.0	COG0637@1|root,COG0637@2|Bacteria,2IZIM@203682|Planctomycetes	203682|Planctomycetes	S	TIGRFAM haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED	-	-	5.4.2.6	ko:K01838	ko00500,map00500	-	R02728,R11310	RC00408	ko00000,ko00001,ko01000	-	-	-	HAD_2
k59_158732_1	572546.Arcpr_0286	4.91e-58	202.0	COG1042@1|root,arCOG01338@2157|Archaea,arCOG01340@2157|Archaea,2XT9G@28890|Euryarchaeota,246RE@183980|Archaeoglobi	183980|Archaeoglobi	C	acetyl coenzyme A synthetase	-	-	6.2.1.13	ko:K01905,ko:K22224	ko00010,ko00620,ko00640,ko01100,ko01120,map00010,map00620,map00640,map01100,map01120	-	R00229,R00920	RC00004,RC00012,RC00014	ko00000,ko00001,ko01000,ko01004	-	-	-	ATP-grasp_5,CoA_binding_2,Succ_CoA_lig
k59_52186_2	1121405.dsmv_1953	4.17e-21	92.0	COG0674@1|root,COG0674@2|Bacteria,1MVM0@1224|Proteobacteria,42MZ0@68525|delta/epsilon subdivisions,2WJG3@28221|Deltaproteobacteria,2MJ3H@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Pyruvate:ferredoxin oxidoreductase core domain II	-	-	1.2.7.1	ko:K00169	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR_N
k59_226720_2	880072.Desac_1954	2.65e-33	126.0	COG1560@1|root,COG1560@2|Bacteria	2|Bacteria	M	Kdo2-lipid A biosynthetic process	waaM	-	2.3.1.241	ko:K02517	ko00540,ko01100,map00540,map01100	M00060	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Lip_A_acyltrans
k59_241705_1	709991.Odosp_2642	2.08e-31	125.0	COG3014@1|root,COG3014@2|Bacteria,4NIIU@976|Bacteroidetes,2FQVB@200643|Bacteroidia	976|Bacteroidetes	S	protein conserved in bacteria	-	-	-	ko:K09859	-	-	-	-	ko00000	-	-	-	TPR_2
k59_52188_1	177437.HRM2_29500	2e-89	273.0	COG2304@1|root,COG2304@2|Bacteria,1MXQ7@1224|Proteobacteria,42NWB@68525|delta/epsilon subdivisions,2WKKE@28221|Deltaproteobacteria,2MIJF@213118|Desulfobacterales	28221|Deltaproteobacteria	S	PFAM von Willebrand factor type A domain	batA	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	BatA,VWA
k59_113427_1	1121405.dsmv_2321	1.52e-24	94.0	2ESBH@1|root,33JW8@2|Bacteria,1P6U8@1224|Proteobacteria,4339B@68525|delta/epsilon subdivisions,2WXC0@28221|Deltaproteobacteria,2MP2H@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_143900_1	1265505.ATUG01000003_gene347	2.3e-251	712.0	COG0243@1|root,COG3383@1|root,COG0243@2|Bacteria,COG3383@2|Bacteria,1MW3N@1224|Proteobacteria,43BJY@68525|delta/epsilon subdivisions,2WIWD@28221|Deltaproteobacteria,2MIG4@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	fdnG-2	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding,TAT_signal
k59_67347_1	643562.Daes_2398	3.41e-20	90.5	COG5003@1|root,COG5003@2|Bacteria,1NG1Q@1224|Proteobacteria,431VF@68525|delta/epsilon subdivisions,2WWIA@28221|Deltaproteobacteria,2MDJJ@213115|Desulfovibrionales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF1834
k59_67347_2	998088.B565_1781	2.97e-10	62.4	COG5005@1|root,COG5005@2|Bacteria,1QEN5@1224|Proteobacteria,1TBEQ@1236|Gammaproteobacteria,1Y5RK@135624|Aeromonadales	135624|Aeromonadales	S	Phage virion morphogenesis family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_tail_S
k59_143901_1	667014.Thein_0620	6.6e-47	157.0	COG0634@1|root,COG0634@2|Bacteria,2GH72@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	F	Belongs to the purine pyrimidine phosphoribosyltransferase family	-	-	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
k59_158740_1	596151.DesfrDRAFT_3310	5.56e-48	171.0	COG0243@1|root,COG0243@2|Bacteria,1NR6J@1224|Proteobacteria,43BMM@68525|delta/epsilon subdivisions,2WJJV@28221|Deltaproteobacteria,2M9SF@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Molybdopterin,Molydop_binding
k59_219080_1	1499967.BAYZ01000190_gene3817	4.07e-121	361.0	COG1249@1|root,COG1249@2|Bacteria	2|Bacteria	C	cell redox homeostasis	merA	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Pyr_redox_dim
k59_83096_1	1380394.JADL01000004_gene6041	9.75e-109	322.0	COG0473@1|root,COG0473@2|Bacteria,1MUH4@1224|Proteobacteria,2TSBB@28211|Alphaproteobacteria,2JR85@204441|Rhodospirillales	204441|Rhodospirillales	CE	Isocitrate/isopropylmalate dehydrogenase	-	-	1.1.1.83,1.1.1.93,4.1.1.73	ko:K07246	ko00630,ko00650,map00630,map00650	-	R00215,R01751,R02545,R06180	RC00084,RC00105,RC00594	ko00000,ko00001,ko01000	-	-	-	Iso_dh
k59_234927_1	706587.Desti_4338	1.39e-91	278.0	COG2502@1|root,COG2502@2|Bacteria,1MVWF@1224|Proteobacteria	1224|Proteobacteria	E	aspartate--ammonia ligase	asnA	GO:0003674,GO:0003824,GO:0004071,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006528,GO:0006529,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009987,GO:0016053,GO:0016211,GO:0016874,GO:0016879,GO:0016880,GO:0019752,GO:0032787,GO:0033554,GO:0034641,GO:0042802,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050896,GO:0051716,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	6.3.1.1	ko:K01914	ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230	-	R00483	RC00010	ko00000,ko00001,ko01000	-	-	iAPECO1_1312.APECO1_2719,iECOK1_1307.ECOK1_4193,iECS88_1305.ECS88_4166,iUMN146_1321.UM146_18910,iUTI89_1310.UTI89_C4299	AsnA,tRNA-synt_2
k59_90525_1	391625.PPSIR1_31478	1.08e-78	241.0	COG0566@1|root,COG0566@2|Bacteria,1Q9ZD@1224|Proteobacteria,42VPG@68525|delta/epsilon subdivisions	1224|Proteobacteria	J	rRNA methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	SpoU_methylase
k59_177490_1	1121405.dsmv_0406	1.78e-64	206.0	COG0694@1|root,COG0822@1|root,COG0694@2|Bacteria,COG0822@2|Bacteria,1RD5K@1224|Proteobacteria,42MT6@68525|delta/epsilon subdivisions,2WJBU@28221|Deltaproteobacteria,2MIAE@213118|Desulfobacterales	28221|Deltaproteobacteria	C	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins	nifU	-	-	ko:K04488,ko:K13819	-	-	-	-	ko00000	-	-	-	Fer2_BFD,NifU,NifU_N
k59_79125_1	335543.Sfum_2170	9.12e-25	95.9	2AVEY@1|root,31M6X@2|Bacteria,1QJ1U@1224|Proteobacteria,4322P@68525|delta/epsilon subdivisions,2WWRT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4389)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4389
k59_79125_2	1536773.R70331_18765	4.88e-22	93.2	COG0667@1|root,COG0667@2|Bacteria,1TPIY@1239|Firmicutes,4HA4Q@91061|Bacilli,26S2B@186822|Paenibacillaceae	91061|Bacilli	C	aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
k59_185504_1	879212.DespoDRAFT_01781	3.73e-43	155.0	COG0457@1|root,COG0457@2|Bacteria,1R64F@1224|Proteobacteria,42Q6D@68525|delta/epsilon subdivisions,2WKT0@28221|Deltaproteobacteria,2MHV1@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4388)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388
k59_109116_1	1047013.AQSP01000092_gene323	1.58e-69	221.0	COG0798@1|root,COG0798@2|Bacteria,2NNWJ@2323|unclassified Bacteria	2|Bacteria	P	Sodium Bile acid symporter family	arsB	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015104,GO:0015105,GO:0015291,GO:0015297,GO:0015318,GO:0015698,GO:0015699,GO:0015700,GO:0016020,GO:0022804,GO:0022857,GO:0034220,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656	-	ko:K03325	-	-	-	-	ko00000,ko02000	2.A.59	-	-	SBF
k59_10824_2	522772.Dacet_2483	4.22e-31	119.0	COG0803@1|root,COG0803@2|Bacteria,2GFQW@200930|Deferribacteres	200930|Deferribacteres	P	Zinc-uptake complex component A periplasmic	-	-	-	ko:K09815	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ZnuA
k59_192654_1	933262.AXAM01000069_gene2684	2.14e-138	404.0	COG1190@1|root,COG1190@2|Bacteria,1MX1V@1224|Proteobacteria,42M90@68525|delta/epsilon subdivisions,2WJ9G@28221|Deltaproteobacteria,2MHV2@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Belongs to the class-II aminoacyl-tRNA synthetase family	lysS	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
k59_155037_1	1029823.AFIE01000007_gene1881	1.82e-37	147.0	COG0454@1|root,COG0553@1|root,COG0827@1|root,COG1040@1|root,COG4646@1|root,COG0456@2|Bacteria,COG0553@2|Bacteria,COG0827@2|Bacteria,COG1040@2|Bacteria,COG4646@2|Bacteria,1MXQH@1224|Proteobacteria,1T52I@1236|Gammaproteobacteria,3NTTI@468|Moraxellaceae	1236|Gammaproteobacteria	L	methylase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_223185_1	1125863.JAFN01000001_gene1185	2.45e-08	55.1	COG2984@1|root,COG2984@2|Bacteria,1RGC0@1224|Proteobacteria,42RUZ@68525|delta/epsilon subdivisions,2WNIM@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	ABC transporter substrate binding protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC_sub_bind
k59_56944_1	335543.Sfum_0169	4.9e-91	280.0	COG0006@1|root,COG0006@2|Bacteria,1MUZS@1224|Proteobacteria,42M1K@68525|delta/epsilon subdivisions,2WJ8E@28221|Deltaproteobacteria,2MR2W@213462|Syntrophobacterales	28221|Deltaproteobacteria	E	Creatinase/Prolidase N-terminal domain	-	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Creatinase_N,Creatinase_N_2,Peptidase_M24,Peptidase_M24_C
k59_155498_1	102107.XP_008231034.1	2.62e-12	67.4	COG1028@1|root,KOG0725@2759|Eukaryota,37NDT@33090|Viridiplantae,3G740@35493|Streptophyta,4JIBX@91835|fabids	35493|Streptophyta	Q	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
k59_200831_1	589865.DaAHT2_2116	5.72e-13	70.5	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	NHL,TPR_11
k59_132694_1	913325.N799_08335	1.9e-13	75.5	COG2982@1|root,COG2982@2|Bacteria,1MUAN@1224|Proteobacteria,1RNZM@1236|Gammaproteobacteria,1X4Z4@135614|Xanthomonadales	135614|Xanthomonadales	M	protein involved in outer membrane biogenesis	asmA	-	-	ko:K07290	-	-	-	-	ko00000	9.B.121	-	-	AsmA
k59_79650_1	1499967.BAYZ01000028_gene1307	3.34e-60	197.0	COG4177@1|root,COG4177@2|Bacteria,2NPMP@2323|unclassified Bacteria	2|Bacteria	U	Branched-chain amino acid transport system / permease component	livM	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
k59_79650_2	1499967.BAYZ01000028_gene1308	7.26e-107	314.0	COG0411@1|root,COG0411@2|Bacteria,2NNYG@2323|unclassified Bacteria	2|Bacteria	E	Branched-chain amino acid ATP-binding cassette transporter	livG	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
k59_140307_1	439235.Dalk_0554	5.01e-73	238.0	COG0144@1|root,COG0781@1|root,COG0144@2|Bacteria,COG0781@2|Bacteria,1MWPE@1224|Proteobacteria,42P2T@68525|delta/epsilon subdivisions,2WJ9B@28221|Deltaproteobacteria,2MI5Y@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA	rsmB	-	2.1.1.176	ko:K03500	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F,Methyltr_RsmF_N,NusB
k59_231341_1	1348583.ATLH01000022_gene2237	2.35e-50	171.0	COG1044@1|root,COG1044@2|Bacteria,4NH6I@976|Bacteroidetes,1HXDW@117743|Flavobacteriia,1F7VV@104264|Cellulophaga	976|Bacteroidetes	M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	-	-	2.3.1.191	ko:K02536	ko00540,ko01100,map00540,map01100	M00060	R04550	RC00039,RC00166	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hexapep,Hexapep_2,LpxD
k59_186044_1	196490.AUEZ01000147_gene5841	3.59e-32	125.0	COG3547@1|root,COG3547@2|Bacteria,1MW0N@1224|Proteobacteria,2TUGE@28211|Alphaproteobacteria,3JX5I@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	L	PFAM transposase IS116 IS110 IS902 family	-	-	-	ko:K07486	-	-	-	-	ko00000	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_215797_1	933262.AXAM01000011_gene1755	5.85e-66	218.0	COG0493@1|root,COG0493@2|Bacteria,1MU2H@1224|Proteobacteria,42P5P@68525|delta/epsilon subdivisions,2WITN@28221|Deltaproteobacteria,2MJ25@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_20,Fer4_9,Pyr_redox_2
k59_26138_1	1121405.dsmv_1738	4.18e-61	193.0	COG2077@1|root,COG2077@2|Bacteria,1RAJ9@1224|Proteobacteria,42RE8@68525|delta/epsilon subdivisions,2WNA5@28221|Deltaproteobacteria,2MK12@213118|Desulfobacterales	28221|Deltaproteobacteria	O	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides	tpx	-	1.11.1.15	ko:K11065	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA,Redoxin
k59_102417_1	1304872.JAGC01000009_gene513	7.4e-79	254.0	COG2414@1|root,COG2414@2|Bacteria,1MWBB@1224|Proteobacteria,42NR7@68525|delta/epsilon subdivisions,2WK49@28221|Deltaproteobacteria,2MAC0@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	PFAM Aldehyde ferredoxin oxidoreductase	-	-	1.2.7.5	ko:K03738	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00309	R08571	RC00242	ko00000,ko00001,ko00002,ko01000	-	-	-	AFOR_C,AFOR_N
k59_170478_1	1265505.ATUG01000001_gene2887	8.23e-98	315.0	COG1061@1|root,COG1205@1|root,COG1061@2|Bacteria,COG1205@2|Bacteria,1QU0I@1224|Proteobacteria,42M4R@68525|delta/epsilon subdivisions,2WK1V@28221|Deltaproteobacteria,2MI86@213118|Desulfobacterales	28221|Deltaproteobacteria	L	DEAD DEAH box helicase	yprA	-	-	ko:K06877	-	-	-	-	ko00000	-	-	-	DEAD,DUF1998,Helicase_C,RNase_H_2
k59_231348_1	1265505.ATUG01000003_gene40	7.81e-60	191.0	COG0310@1|root,COG0310@2|Bacteria,1RJRC@1224|Proteobacteria,42QZ5@68525|delta/epsilon subdivisions,2WMQX@28221|Deltaproteobacteria,2MJJ5@213118|Desulfobacterales	28221|Deltaproteobacteria	P	PFAM cobalamin (vitamin B12) biosynthesis CbiM protein	-	-	-	ko:K02007	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	CbiM
k59_26139_1	335543.Sfum_2658	3.92e-51	178.0	COG2204@1|root,COG4191@1|root,COG2204@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MFW@68525|delta/epsilon subdivisions,2WKMP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,PAS,PAS_3,PAS_9,Response_reg
k59_125268_1	1032480.MLP_08320	1.08e-19	89.7	COG0350@1|root,COG0350@2|Bacteria,2GKA9@201174|Actinobacteria,4DQTU@85009|Propionibacteriales	201174|Actinobacteria	L	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated	ogt	-	2.1.1.63	ko:K00567	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_binding_1,Methyltransf_1N
k59_34110_1	644282.Deba_3201	9.81e-76	235.0	COG1013@1|root,COG1013@2|Bacteria,1MUY9@1224|Proteobacteria,42MQY@68525|delta/epsilon subdivisions,2WJGJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM Thiamine pyrophosphate	-	-	1.2.7.1	ko:K00170	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
k59_56966_1	1125863.JAFN01000001_gene1735	1.74e-39	142.0	COG0559@1|root,COG0559@2|Bacteria,1MVND@1224|Proteobacteria,42RHF@68525|delta/epsilon subdivisions,2WNRC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	PFAM Branched-chain amino acid transport system permease component	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
k59_200849_2	329726.AM1_G0160	2.37e-09	59.7	COG1357@1|root,COG1357@2|Bacteria	2|Bacteria	S	protein homooligomerization	-	-	-	-	-	-	-	-	-	-	-	-	Ion_trans_2,Pentapeptide,Pentapeptide_4
k59_79661_1	335543.Sfum_3097	1.06e-63	223.0	COG2937@1|root,COG2937@2|Bacteria,1MWZ6@1224|Proteobacteria,42MN4@68525|delta/epsilon subdivisions,2WJJ5@28221|Deltaproteobacteria,2MR0U@213462|Syntrophobacterales	28221|Deltaproteobacteria	I	Belongs to the GPAT DAPAT family	plsB	-	2.3.1.15	ko:K00631	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
k59_26140_1	1206730.BAGA01000081_gene772	2.72e-38	142.0	COG1090@1|root,COG4276@1|root,COG1090@2|Bacteria,COG4276@2|Bacteria,2GJS0@201174|Actinobacteria,4FX6N@85025|Nocardiaceae	201174|Actinobacteria	S	Domain of unknown function (DUF1731)	-	-	-	ko:K07071	-	-	-	-	ko00000	-	-	-	DUF1731,Epimerase
k59_170483_1	56780.SYN_01402	1.92e-74	236.0	COG4956@1|root,COG4956@2|Bacteria,1R9ZM@1224|Proteobacteria,42RC7@68525|delta/epsilon subdivisions,2WMYJ@28221|Deltaproteobacteria,2MQVJ@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Large family of predicted nucleotide-binding domains	-	-	-	-	-	-	-	-	-	-	-	-	TRAM
k59_18596_1	1227488.C477_14268	0.000916	44.3	COG0784@1|root,arCOG02333@2157|Archaea,2XST7@28890|Euryarchaeota,23S1Y@183963|Halobacteria	183963|Halobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,PAS_4,Response_reg
k59_18596_2	485916.Dtox_1913	2.11e-25	108.0	COG3829@1|root,COG3829@2|Bacteria,1TP0E@1239|Firmicutes,247MB@186801|Clostridia,26403@186807|Peptococcaceae	186801|Clostridia	KT	Sigma-54 interaction domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,HTH_8,PAS,PAS_9,Sigma54_activat
k59_170485_1	96561.Dole_0748	3.19e-31	117.0	COG2221@1|root,COG2221@2|Bacteria,1R5F8@1224|Proteobacteria,42PB3@68525|delta/epsilon subdivisions,2WKJR@28221|Deltaproteobacteria,2MHQY@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Proto-chlorophyllide reductase 57 kD subunit	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_6,Fer4_7,NIR_SIR,PCP_red
k59_238536_1	439235.Dalk_0268	2.35e-60	203.0	COG5421@1|root,COG5421@2|Bacteria,1R3NX@1224|Proteobacteria,42QDV@68525|delta/epsilon subdivisions,2WIRQ@28221|Deltaproteobacteria,2MN1S@213118|Desulfobacterales	28221|Deltaproteobacteria	L	PFAM transposase IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
k59_102429_1	335543.Sfum_1261	4.72e-64	208.0	COG1533@1|root,COG1533@2|Bacteria,1NWJ9@1224|Proteobacteria,42P30@68525|delta/epsilon subdivisions,2WIPV@28221|Deltaproteobacteria,2MQE9@213462|Syntrophobacterales	28221|Deltaproteobacteria	L	radical SAM domain protein	-	-	4.1.99.14	ko:K03716	-	-	-	-	ko00000,ko01000	-	-	-	-
k59_208670_1	555779.Dthio_PD1799	3.26e-54	192.0	COG1924@1|root,COG3580@1|root,COG1924@2|Bacteria,COG3580@2|Bacteria,1PKG6@1224|Proteobacteria,42MY4@68525|delta/epsilon subdivisions,2WJFI@28221|Deltaproteobacteria,2M8T9@213115|Desulfovibrionales	28221|Deltaproteobacteria	I	ATPase BadF BadG BcrA BcrD type	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG,DUF2229
k59_3212_1	166318.Syn8016DRAFT_1957	0.000424	48.1	COG0661@1|root,COG0661@2|Bacteria,1G0X9@1117|Cyanobacteria,1GYBK@1129|Synechococcus	1117|Cyanobacteria	S	unusual protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	ABC1
k59_94699_1	933262.AXAM01000046_gene136	3.57e-94	291.0	COG0606@1|root,COG0606@2|Bacteria,1MU4R@1224|Proteobacteria,42NBJ@68525|delta/epsilon subdivisions,2WJ52@28221|Deltaproteobacteria,2MHQI@213118|Desulfobacterales	28221|Deltaproteobacteria	O	chelatase, subunit ChlI	comM	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
k59_11528_1	1123053.AUDG01000130_gene3975	2.14e-16	73.9	COG3666@1|root,COG3666@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_6,DUF772
k59_41429_1	396588.Tgr7_0102	3.2e-07	51.6	COG0452@1|root,COG0452@2|Bacteria,1MVQP@1224|Proteobacteria,1RMKQ@1236|Gammaproteobacteria,1WXCF@135613|Chromatiales	135613|Chromatiales	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	-	-	4.1.1.36,6.3.2.5	ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
k59_41429_3	316067.Geob_3315	9.38e-33	119.0	COG0778@1|root,COG0778@2|Bacteria,1RECN@1224|Proteobacteria,42SPP@68525|delta/epsilon subdivisions,2WPPZ@28221|Deltaproteobacteria,43VP5@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Putative TM nitroreductase	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
k59_238544_1	1232437.KL662006_gene4420	5.07e-46	168.0	COG0769@1|root,COG0770@1|root,COG0769@2|Bacteria,COG0770@2|Bacteria,1QTSF@1224|Proteobacteria,43BV1@68525|delta/epsilon subdivisions,2X760@28221|Deltaproteobacteria,2MPKR@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	-	6.3.2.10,6.3.2.13	ko:K15792	ko00300,ko00550,map00300,map00550	-	R02788,R04617	RC00064,RC00090,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
k59_186085_1	1121405.dsmv_3828	7.67e-94	292.0	COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,42M6J@68525|delta/epsilon subdivisions,2WJZQ@28221|Deltaproteobacteria,2MJ1A@213118|Desulfobacterales	28221|Deltaproteobacteria	I	PFAM 3-hydroxyacyl-CoA dehydrogenase	-	-	1.1.1.157,1.1.1.35,4.2.1.17	ko:K00074,ko:K15016	ko00360,ko00362,ko00650,ko00720,ko01100,ko01120,ko01200,map00360,map00362,map00650,map00720,map01100,map01120,map01200	M00374,M00375	R01975,R01976,R03026,R05576,R06941	RC00029,RC00117,RC00831	ko00000,ko00001,ko00002,ko01000	-	-	-	3HCDH,3HCDH_N
k59_49019_1	1528106.JRJE01000005_gene1259	1.54e-70	225.0	COG1804@1|root,COG1804@2|Bacteria,1MU2K@1224|Proteobacteria,2TR7Q@28211|Alphaproteobacteria,2JQKF@204441|Rhodospirillales	204441|Rhodospirillales	C	III protein, CoA-transferase family	-	-	2.8.3.16	ko:K07749	-	-	-	-	ko00000,ko01000	-	-	-	CoA_transf_3
k59_200872_1	903818.KI912268_gene1348	7.59e-52	176.0	COG0598@1|root,COG0598@2|Bacteria	2|Bacteria	P	Magnesium transport protein CorA	zntB	GO:0000041,GO:0003674,GO:0005215,GO:0005385,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006829,GO:0008150,GO:0008324,GO:0015075,GO:0015318,GO:0015562,GO:0016020,GO:0016021,GO:0022857,GO:0022883,GO:0022890,GO:0030001,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0046583,GO:0046873,GO:0046915,GO:0051179,GO:0051234,GO:0055085,GO:0070838,GO:0071577,GO:0071944,GO:0072509,GO:0072511,GO:0098655,GO:0098660,GO:0098662	-	ko:K03284,ko:K16074	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3,1.A.35.4	-	-	CorA
k59_215829_1	1449076.JOOE01000004_gene3	4.75e-06	55.8	COG1357@1|root,COG2931@1|root,COG3210@1|root,COG1357@2|Bacteria,COG2931@2|Bacteria,COG3210@2|Bacteria,1MU7T@1224|Proteobacteria,2TRVY@28211|Alphaproteobacteria,2K78I@204457|Sphingomonadales	204457|Sphingomonadales	Q	Haemolysin-type calcium-binding repeat (2 copies)	-	-	-	-	-	-	-	-	-	-	-	-	HemolysinCabind,VCBS
k59_155541_1	1391647.AVSV01000002_gene1277	6.19e-45	154.0	COG1268@1|root,COG1268@2|Bacteria,1VAY6@1239|Firmicutes,24HU5@186801|Clostridia,36DWS@31979|Clostridiaceae	186801|Clostridia	S	hmm pf02632	bioY	-	-	ko:K03523	ko02010,map02010	M00581,M00582	-	-	ko00000,ko00001,ko00002,ko02000	2.A.88.1,2.A.88.2	-	-	BioY
k59_186092_1	246197.MXAN_5604	1.45e-06	50.4	COG0707@1|root,COG0707@2|Bacteria,1MVIB@1224|Proteobacteria,42ME1@68525|delta/epsilon subdivisions,2WJNY@28221|Deltaproteobacteria,2YWEZ@29|Myxococcales	28221|Deltaproteobacteria	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
k59_186092_2	177437.HRM2_12700	3.12e-43	152.0	COG0772@1|root,COG0772@2|Bacteria,1MVDB@1224|Proteobacteria,42MG2@68525|delta/epsilon subdivisions,2WJ01@28221|Deltaproteobacteria,2MIUK@213118|Desulfobacterales	28221|Deltaproteobacteria	D	Belongs to the SEDS family	ftsW	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
k59_79697_1	56780.SYN_01266	2.18e-51	174.0	COG2853@1|root,COG2853@2|Bacteria,1MVX0@1224|Proteobacteria,42RII@68525|delta/epsilon subdivisions,2WNS9@28221|Deltaproteobacteria,2MQHA@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	MlaA lipoprotein	-	-	-	ko:K04754	-	-	-	-	ko00000	-	-	-	MlaA
k59_86898_1	1232437.KL661989_gene468	2.84e-36	134.0	COG1509@1|root,COG1509@2|Bacteria,1MUPJ@1224|Proteobacteria,42NCM@68525|delta/epsilon subdivisions,2WKN6@28221|Deltaproteobacteria,2MIXH@213118|Desulfobacterales	28221|Deltaproteobacteria	E	lysine 2,3-aminomutase	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_14
k59_162769_1	335543.Sfum_3470	1.68e-85	268.0	COG0773@1|root,COG0773@2|Bacteria,1MV68@1224|Proteobacteria,42MMP@68525|delta/epsilon subdivisions,2WK50@28221|Deltaproteobacteria,2MR03@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	Belongs to the MurCDEF family	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
k59_94719_1	1121405.dsmv_3556	9.58e-86	267.0	COG0701@1|root,COG0701@2|Bacteria,1MUN8@1224|Proteobacteria,42N6E@68525|delta/epsilon subdivisions,2WJXG@28221|Deltaproteobacteria,2MJ1N@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Predicted permease	-	-	-	ko:K07089	-	-	-	-	ko00000	-	-	-	ArsP_1
k59_125303_1	1122217.KB899574_gene2035	7.74e-52	179.0	COG0770@1|root,COG0770@2|Bacteria,1VT78@1239|Firmicutes,4H1XX@909932|Negativicutes	909932|Negativicutes	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
k59_208703_1	670292.JH26_25195	4.06e-61	208.0	COG4251@1|root,COG4251@2|Bacteria,1NSQ1@1224|Proteobacteria,2TWHG@28211|Alphaproteobacteria,1JSRP@119045|Methylobacteriaceae	28211|Alphaproteobacteria	T	Phytochrome central region domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF4118,GAF,HATPase_c,HisKA,PAS_2,PHY,Response_reg
k59_170529_1	96561.Dole_1510	1.46e-90	282.0	COG0823@1|root,COG0823@2|Bacteria,1NR8W@1224|Proteobacteria,42YPB@68525|delta/epsilon subdivisions,2WTWD@28221|Deltaproteobacteria	28221|Deltaproteobacteria	U	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	PD40
k59_26167_1	82654.Pse7367_3279	4.27e-39	145.0	COG1160@1|root,COG1160@2|Bacteria,1G00M@1117|Cyanobacteria,1H8RI@1150|Oscillatoriales	1117|Cyanobacteria	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	-	1.1.1.399,1.1.1.95	ko:K00058,ko:K03977	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko03009,ko04147	-	-	-	KH_dom-like,MMR_HSR1
k59_94724_1	756272.Plabr_0785	8.62e-101	328.0	COG2373@1|root,COG2373@2|Bacteria,2IWRT@203682|Planctomycetes	203682|Planctomycetes	S	Large extracellular alpha-helical protein	-	-	-	ko:K06894	-	-	-	-	ko00000	-	-	-	A2M,A2M_N,A2M_N_2,A2M_comp,Thiol-ester_cl
k59_232808_1	1209072.ALBT01000067_gene102	2.94e-46	164.0	COG0673@1|root,COG0673@2|Bacteria,1MZIG@1224|Proteobacteria,1RS5T@1236|Gammaproteobacteria,1FFYF@10|Cellvibrio	1236|Gammaproteobacteria	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
k59_4660_1	56780.SYN_01264	1.24e-61	194.0	COG1463@1|root,COG1463@2|Bacteria,1NCUG@1224|Proteobacteria,42SCT@68525|delta/epsilon subdivisions,2WPA7@28221|Deltaproteobacteria,2MQJI@213462|Syntrophobacterales	28221|Deltaproteobacteria	Q	MlaD protein	-	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
k59_4662_1	1121405.dsmv_3761	2.16e-33	116.0	2E496@1|root,32Z4Y@2|Bacteria,1NE0Q@1224|Proteobacteria,42VS6@68525|delta/epsilon subdivisions,2WRXJ@28221|Deltaproteobacteria,2MKUT@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_4662_2	1121405.dsmv_1271	1.69e-30	116.0	COG0589@1|root,COG0589@2|Bacteria,1NY54@1224|Proteobacteria	1224|Proteobacteria	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
k59_210637_2	1094980.Mpsy_2024	8.03e-25	102.0	COG1260@1|root,arCOG04213@2157|Archaea,2XVGK@28890|Euryarchaeota,2N96M@224756|Methanomicrobia	224756|Methanomicrobia	I	Myo-inositol-1-phosphate synthase	-	-	5.5.1.4	ko:K01858	ko00521,ko00562,ko01100,ko01130,map00521,map00562,map01100,map01130	-	R07324	RC01804	ko00000,ko00001,ko01000	-	-	-	Inos-1-P_synth
k59_59020_1	1265505.ATUG01000002_gene980	2.94e-73	224.0	COG2030@1|root,COG2030@2|Bacteria,1N4UG@1224|Proteobacteria,430GB@68525|delta/epsilon subdivisions,2WW0S@28221|Deltaproteobacteria,2MNJV@213118|Desulfobacterales	28221|Deltaproteobacteria	I	MaoC like domain	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
k59_240182_1	933262.AXAM01000034_gene1563	1.46e-110	335.0	COG2885@1|root,COG3267@1|root,COG2885@2|Bacteria,COG3267@2|Bacteria,1MU3G@1224|Proteobacteria,42PJ3@68525|delta/epsilon subdivisions,2WJF6@28221|Deltaproteobacteria,2MJ4S@213118|Desulfobacterales	28221|Deltaproteobacteria	MU	AAA domain	-	-	-	ko:K02450	-	M00331	-	-	ko00000,ko00002,ko02044	9.B.42	-	-	AAA_22,OmpA
k59_88864_1	1469245.JFBG01000011_gene839	4.45e-25	108.0	COG0747@1|root,COG0747@2|Bacteria,1MUZH@1224|Proteobacteria	1224|Proteobacteria	E	ABC-Type Dipeptide Transport System Periplasmic Component	appA	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
k59_96610_1	583355.Caka_2662	2.2e-08	62.0	COG1808@1|root,COG1808@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF389)	-	-	-	-	-	-	-	-	-	-	-	-	DUF389
k59_179460_1	1121396.KB893100_gene4318	6.62e-28	104.0	COG1908@1|root,COG1908@2|Bacteria,1RCZY@1224|Proteobacteria,42RJZ@68525|delta/epsilon subdivisions,2WNDU@28221|Deltaproteobacteria,2MJUB@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Methyl-viologen-reducing hydrogenase, delta subunit	-	-	-	-	-	-	-	-	-	-	-	-	FlpD
k59_179460_2	933262.AXAM01000017_gene3142	5.91e-50	167.0	COG1035@1|root,COG4656@1|root,COG1035@2|Bacteria,COG4656@2|Bacteria,1NQN7@1224|Proteobacteria,42MGI@68525|delta/epsilon subdivisions,2WKNC@28221|Deltaproteobacteria,2MIJN@213118|Desulfobacterales	28221|Deltaproteobacteria	C	4Fe-4S ferredoxin iron-sulfur binding domain protein	hdrD	-	-	-	-	-	-	-	-	-	-	-	Fer4_10,Fer4_17,Fer4_8,FlpD,FrhB_FdhB_C
k59_202933_1	1184267.A11Q_2296	1.33e-58	200.0	COG0578@1|root,COG0578@2|Bacteria,1MUMY@1224|Proteobacteria,42N1B@68525|delta/epsilon subdivisions,2MSWP@213481|Bdellovibrionales,2WJWS@28221|Deltaproteobacteria	213481|Bdellovibrionales	C	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family	glpD	-	1.1.5.3	ko:K00111	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	DAO,DAO_C
k59_59042_1	706587.Desti_4338	1.11e-99	300.0	COG2502@1|root,COG2502@2|Bacteria,1MVWF@1224|Proteobacteria	1224|Proteobacteria	E	aspartate--ammonia ligase	asnA	GO:0003674,GO:0003824,GO:0004071,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006528,GO:0006529,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009987,GO:0016053,GO:0016211,GO:0016874,GO:0016879,GO:0016880,GO:0019752,GO:0032787,GO:0033554,GO:0034641,GO:0042802,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050896,GO:0051716,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	6.3.1.1	ko:K01914	ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230	-	R00483	RC00010	ko00000,ko00001,ko01000	-	-	iAPECO1_1312.APECO1_2719,iECOK1_1307.ECOK1_4193,iECS88_1305.ECS88_4166,iUMN146_1321.UM146_18910,iUTI89_1310.UTI89_C4299	AsnA,tRNA-synt_2
k59_134845_1	398767.Glov_1611	6.37e-63	209.0	COG1249@1|root,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,42N8Y@68525|delta/epsilon subdivisions,2WIR7@28221|Deltaproteobacteria,43SUM@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	pyridine nucleotide-disulphide oxidoreductase dimerisation region	lpdA-1	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
k59_240205_1	1121456.ATVA01000015_gene2238	6.32e-91	285.0	COG0446@1|root,COG0607@1|root,COG0446@2|Bacteria,COG0607@2|Bacteria,1NR3M@1224|Proteobacteria,42N3G@68525|delta/epsilon subdivisions,2WIS9@28221|Deltaproteobacteria,2M89U@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	Pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Pyr_redox_dim,Rhodanese
k59_188065_1	439235.Dalk_2057	2.98e-95	296.0	COG0041@1|root,COG0151@1|root,COG0041@2|Bacteria,COG0151@2|Bacteria,1MUAH@1224|Proteobacteria,42MCI@68525|delta/epsilon subdivisions,2WJ7H@28221|Deltaproteobacteria,2MIPF@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC,GARS_A,GARS_C,GARS_N
k59_111786_1	335543.Sfum_3055	2.85e-96	298.0	COG1219@1|root,COG1219@2|Bacteria,1MWIZ@1224|Proteobacteria,42N1Z@68525|delta/epsilon subdivisions,2WJUS@28221|Deltaproteobacteria,2MR6M@213462|Syntrophobacterales	28221|Deltaproteobacteria	O	Belongs to the ClpX chaperone family	-	-	-	-	-	-	-	-	-	-	-	-	AAA_2,ClpB_D2-small
k59_65853_1	768671.ThimaDRAFT_1468	7.22e-55	184.0	COG3591@1|root,COG3591@2|Bacteria,1R8DB@1224|Proteobacteria,1SID9@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Belongs to the peptidase S1B family	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_111793_1	1131266.ARWQ01000008_gene297	1.87e-09	54.7	COG2835@1|root,arCOG04124@2157|Archaea,41STB@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Trm112p-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Trm112p
k59_118860_1	1121438.JNJA01000004_gene577	1.79e-78	249.0	COG1566@1|root,COG1566@2|Bacteria,1MWG0@1224|Proteobacteria,42NAT@68525|delta/epsilon subdivisions,2WPPB@28221|Deltaproteobacteria,2MBTW@213115|Desulfovibrionales	28221|Deltaproteobacteria	V	Biotin-lipoyl like	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
k59_118860_2	768671.ThimaDRAFT_0872	2.31e-52	182.0	COG1289@1|root,COG1289@2|Bacteria,1QJEM@1224|Proteobacteria,1SMXK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Aromatic acid exporter family member 1	VPA1578	-	-	-	-	-	-	-	-	-	-	-	FUSC
k59_36192_2	177437.HRM2_00810	4.8e-25	102.0	COG0247@1|root,COG0247@2|Bacteria,1N5Q2@1224|Proteobacteria,42P5D@68525|delta/epsilon subdivisions,2WJ9I@28221|Deltaproteobacteria,2MI9D@213118|Desulfobacterales	28221|Deltaproteobacteria	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_17,Fer4_8,Fer4_9
k59_240223_1	1121405.dsmv_3380	2.56e-58	182.0	COG4802@1|root,COG4802@2|Bacteria,1RI70@1224|Proteobacteria,42SXJ@68525|delta/epsilon subdivisions,2WP19@28221|Deltaproteobacteria,2MKJ4@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM Ferredoxin thioredoxin reductase catalytic beta chain	-	-	-	-	-	-	-	-	-	-	-	-	FeThRed_B
k59_233521_1	335543.Sfum_2805	2.33e-44	154.0	COG0509@1|root,COG0509@2|Bacteria,1Q1KI@1224|Proteobacteria,437BG@68525|delta/epsilon subdivisions,2X2GI@28221|Deltaproteobacteria,2MRJR@213462|Syntrophobacterales	28221|Deltaproteobacteria	E	PFAM glycine cleavage H-protein	-	-	-	-	-	-	-	-	-	-	-	-	GCV_H
k59_111803_1	756883.Halar_1646	1.7e-17	87.4	COG0243@1|root,arCOG01492@2157|Archaea	2157|Archaea	C	Formate dehydrogenase Alpha subunit	-	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Fer2_4,Fer4,Fer4_7,Fer4_9,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
k59_65861_1	43989.cce_0439	1.02e-39	148.0	COG1262@1|root,COG1262@2|Bacteria,1G0ZT@1117|Cyanobacteria,3KFP0@43988|Cyanothece	1117|Cyanobacteria	D	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
k59_104356_1	1121405.dsmv_1078	2.03e-142	429.0	COG0243@1|root,COG0243@2|Bacteria,1R4RR@1224|Proteobacteria,42PA5@68525|delta/epsilon subdivisions,2WM0K@28221|Deltaproteobacteria,2MI3Z@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	qrcB	-	-	ko:K08357	ko00920,ko01120,ko02020,map00920,map01120,map02020	-	R10150	RC03109	ko00000,ko00001,ko02000	5.A.3.10	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
k59_118867_1	335543.Sfum_3183	1.45e-83	263.0	COG2262@1|root,COG2262@2|Bacteria,1MUA0@1224|Proteobacteria,42NA6@68525|delta/epsilon subdivisions,2WIMU@28221|Deltaproteobacteria,2MQ6V@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
k59_202976_1	879212.DespoDRAFT_00201	5.14e-20	97.1	COG0642@1|root,COG0745@1|root,COG2984@1|root,COG5002@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria,COG2984@2|Bacteria,COG5002@2|Bacteria,1NRP8@1224|Proteobacteria,42M0Y@68525|delta/epsilon subdivisions,2WIR4@28221|Deltaproteobacteria,2MJA9@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Histidine Phosphotransfer domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,PAS_3,PAS_4,PAS_9,Response_reg,sCache_2
k59_217781_2	439235.Dalk_4509	1.18e-38	141.0	COG3677@1|root,COG3677@2|Bacteria,1MXYX@1224|Proteobacteria,434AT@68525|delta/epsilon subdivisions,2X9GM@28221|Deltaproteobacteria,2MNQ4@213118|Desulfobacterales	28221|Deltaproteobacteria	L	ISXO2-like transposase domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS1595,Zn_Tnp_IS1595
k59_118871_1	1121403.AUCV01000044_gene46	7.84e-96	302.0	COG0659@1|root,COG0659@2|Bacteria,1MWDF@1224|Proteobacteria,43AD6@68525|delta/epsilon subdivisions,2WJCC@28221|Deltaproteobacteria,2MJ5W@213118|Desulfobacterales	28221|Deltaproteobacteria	P	PFAM sulfate transporter	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
k59_210649_1	293826.Amet_3160	1.27e-67	226.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247Q0@186801|Clostridia,36E82@31979|Clostridiaceae	186801|Clostridia	V	ABC transporter transmembrane region	-	-	-	ko:K18890	ko02010,map02010	M00707	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.106.13,3.A.1.106.5	-	-	ABC_membrane,ABC_tran
k59_149153_1	525897.Dbac_3432	1.34e-19	94.0	COG2032@1|root,COG3419@1|root,COG2032@2|Bacteria,COG3419@2|Bacteria,1NUAV@1224|Proteobacteria,42NJ7@68525|delta/epsilon subdivisions,2WKJV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	NU	Tfp pilus assembly protein tip-associated adhesin	pilY1	-	-	ko:K02674	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	Neisseria_PilC,PA14
k59_104362_1	102125.Xen7305DRAFT_00039550	5.42e-19	85.5	COG0385@1|root,COG0385@2|Bacteria,1GJMG@1117|Cyanobacteria,3VNEQ@52604|Pleurocapsales	1117|Cyanobacteria	S	PFAM Sodium Bile acid symporter family	-	-	-	ko:K03453	-	-	-	-	ko00000	2.A.28	-	-	SBF
k59_104362_2	864069.MicloDRAFT_00044120	1.2e-83	252.0	COG3247@1|root,COG3247@2|Bacteria,1R63F@1224|Proteobacteria,2U3AR@28211|Alphaproteobacteria,1JYSN@119045|Methylobacteriaceae	28211|Alphaproteobacteria	S	Short repeat of unknown function (DUF308)	MA20_30435	-	-	-	-	-	-	-	-	-	-	-	DUF308
k59_217782_1	1168034.FH5T_03775	3.02e-198	563.0	COG4565@1|root,COG4584@1|root,COG4565@2|Bacteria,COG4584@2|Bacteria,4NEY6@976|Bacteroidetes,2FMHY@200643|Bacteroidia	976|Bacteroidetes	L	COG4584 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	HTH_11,HTH_23,rve
k59_225149_1	743720.Psefu_0424	1.3e-20	91.3	COG3167@1|root,COG3167@2|Bacteria,1PPTB@1224|Proteobacteria,1SWNN@1236|Gammaproteobacteria,1YZFQ@136845|Pseudomonas putida group	1236|Gammaproteobacteria	NU	Pilus assembly protein, PilO	-	-	-	ko:K02664	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilO
k59_142409_1	880072.Desac_1163	2.7e-111	329.0	COG1852@1|root,COG1852@2|Bacteria,1RAI2@1224|Proteobacteria,42QUD@68525|delta/epsilon subdivisions,2WMQ5@28221|Deltaproteobacteria,2MRCC@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Protein of unknown function DUF116	-	-	-	ko:K09729	-	-	-	-	ko00000	-	-	-	DUF116
k59_202985_1	1230457.C476_15680	4.65e-64	217.0	COG1042@1|root,arCOG01340@2157|Archaea,2XT9G@28890|Euryarchaeota,23UY0@183963|Halobacteria	183963|Halobacteria	C	COG1042 Acyl-CoA synthetase (NDP forming)	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_5,CoA_binding_2,Succ_CoA_lig
k59_36209_1	439235.Dalk_0268	2.48e-95	296.0	COG5421@1|root,COG5421@2|Bacteria,1R3NX@1224|Proteobacteria,42QDV@68525|delta/epsilon subdivisions,2WIRQ@28221|Deltaproteobacteria,2MN1S@213118|Desulfobacterales	28221|Deltaproteobacteria	L	PFAM transposase IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
k59_142413_1	933262.AXAM01000014_gene233	4.83e-113	335.0	COG0003@1|root,COG0071@1|root,COG0003@2|Bacteria,COG0071@2|Bacteria,1MUTX@1224|Proteobacteria,42P0N@68525|delta/epsilon subdivisions,2WKQ0@28221|Deltaproteobacteria,2MJJ2@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Anion-transporting ATPase	-	-	3.6.3.16	ko:K01551	-	-	-	-	ko00000,ko01000,ko02000	3.A.19.1,3.A.21.1,3.A.4.1	-	-	ArsA_ATPase
k59_188103_1	1329516.JPST01000065_gene1811	1.51e-27	113.0	COG0006@1|root,COG0006@2|Bacteria,1TQ44@1239|Firmicutes,4HAT7@91061|Bacilli,27BJY@186824|Thermoactinomycetaceae	91061|Bacilli	E	Creatinase/Prolidase N-terminal domain	pepP	-	3.4.11.9,3.4.13.9	ko:K01262,ko:K01271	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Creatinase_N,Peptidase_M24
k59_65872_1	96561.Dole_3137	1.76e-73	233.0	COG1373@1|root,COG1373@2|Bacteria,1MWBT@1224|Proteobacteria,42NJU@68525|delta/epsilon subdivisions,2WKA6@28221|Deltaproteobacteria,2MJK5@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4143)	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
k59_127155_1	1121396.KB893072_gene1240	6.07e-56	187.0	COG0743@1|root,COG0743@2|Bacteria,1MU4G@1224|Proteobacteria,42NI1@68525|delta/epsilon subdivisions,2WK14@28221|Deltaproteobacteria,2MIFC@213118|Desulfobacterales	28221|Deltaproteobacteria	I	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)	dxr	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576	1.1.1.267	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05688	RC01452	ko00000,ko00001,ko00002,ko01000	-	-	-	DXPR_C,DXP_redisom_C,DXP_reductoisom
k59_217795_2	266264.Rmet_0008	1.32e-68	216.0	COG0395@1|root,COG0395@2|Bacteria,1N4I0@1224|Proteobacteria,2VNEK@28216|Betaproteobacteria,1K9J0@119060|Burkholderiaceae	28216|Betaproteobacteria	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
k59_157362_1	1167006.UWK_00595	6.66e-91	281.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42ME4@68525|delta/epsilon subdivisions,2WJA5@28221|Deltaproteobacteria,2MIGA@213118|Desulfobacterales	28221|Deltaproteobacteria	T	CheY-like receiver, AAA-type ATPase, and DNA-binding	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
k59_157362_2	880072.Desac_1676	4.1e-39	145.0	COG0642@1|root,COG2205@2|Bacteria,1QHXX@1224|Proteobacteria,42NW1@68525|delta/epsilon subdivisions,2WJUF@28221|Deltaproteobacteria,2MR85@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	Histidine kinase-like ATPases	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
k59_50784_1	1094980.Mpsy_2222	9.34e-88	268.0	COG0489@1|root,arCOG00585@2157|Archaea,2XTU2@28890|Euryarchaeota,2N9IC@224756|Methanomicrobia	224756|Methanomicrobia	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	-	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	ParA
k59_88915_1	639282.DEFDS_0744	3.15e-16	84.0	COG2864@1|root,COG2864@2|Bacteria,2GFHK@200930|Deferribacteres	200930|Deferribacteres	C	formate dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_13650_1	237368.SCABRO_01637	3.19e-09	57.8	COG0058@1|root,COG0058@2|Bacteria,2IY0J@203682|Planctomycetes	203682|Planctomycetes	G	COG0058 Glucan phosphorylase	-	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	DUF3417,Phosphorylase
k59_27834_1	273068.TTE0131	1.39e-17	84.3	COG0068@1|root,COG0068@2|Bacteria,1TQM7@1239|Firmicutes,2494A@186801|Clostridia,42EWS@68295|Thermoanaerobacterales	186801|Clostridia	O	Belongs to the carbamoyltransferase HypF family	hypF	-	-	ko:K04656	-	-	-	-	ko00000	-	-	-	Acylphosphatase,Sua5_yciO_yrdC,zf-HYPF
k59_27834_2	1401067.HMPREF0872_06570	9.62e-19	80.1	COG0298@1|root,COG0298@2|Bacteria,1VFE0@1239|Firmicutes,4H5P1@909932|Negativicutes	909932|Negativicutes	O	Hydrogenase assembly chaperone hypC hupF	hypC	-	-	ko:K04653	-	-	-	-	ko00000	-	-	-	HupF_HypC
k59_111834_1	335543.Sfum_0828	1.57e-153	453.0	COG2204@1|root,COG4191@1|root,COG2204@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42PZ5@68525|delta/epsilon subdivisions,2WKB1@28221|Deltaproteobacteria,2MR2G@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	PFAM response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
k59_149170_2	1121918.ARWE01000001_gene239	1.77e-41	150.0	COG2812@1|root,COG2812@2|Bacteria,1MVCK@1224|Proteobacteria,42M09@68525|delta/epsilon subdivisions,2WJ1G@28221|Deltaproteobacteria,43SB5@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	DNA polymerase III subunits gamma and tau domain III	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
k59_188106_1	933262.AXAM01000013_gene1282	1.1e-52	185.0	COG0768@1|root,COG0768@2|Bacteria,1MUNY@1224|Proteobacteria,42M1T@68525|delta/epsilon subdivisions,2WK0W@28221|Deltaproteobacteria,2MI0J@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Penicillin-binding Protein dimerisation domain	ftsI	-	3.4.16.4	ko:K03587	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PASTA,PBP_dimer,Transpeptidase
k59_226505_1	1122194.AUHU01000004_gene1528	7.44e-19	80.1	COG3089@1|root,COG3089@2|Bacteria,1N6TM@1224|Proteobacteria,1SCDE@1236|Gammaproteobacteria,468XY@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Uncharacterised protein family (UPF0270)	yheU	-	-	ko:K09898	-	-	-	-	ko00000	-	-	-	UPF0270
k59_226505_2	1121439.dsat_2172	4.94e-13	70.1	COG1067@1|root,COG1067@2|Bacteria,1MWGB@1224|Proteobacteria,42NJD@68525|delta/epsilon subdivisions,2WJFK@28221|Deltaproteobacteria,2M7U6@213115|Desulfovibrionales	28221|Deltaproteobacteria	O	Belongs to the peptidase S16 family	-	-	3.4.21.53	ko:K01338,ko:K04076,ko:K04770	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA_32,Lon_C
k59_21641_1	1449346.JQMO01000003_gene5819	8.84e-17	79.3	COG2197@1|root,COG2197@2|Bacteria,2GIXB@201174|Actinobacteria,2M448@2063|Kitasatospora	201174|Actinobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
k59_136108_1	1121405.dsmv_3476	6.89e-244	701.0	COG0495@1|root,COG0495@2|Bacteria,1MV47@1224|Proteobacteria,42MRQ@68525|delta/epsilon subdivisions,2WJ3E@28221|Deltaproteobacteria,2MJ6A@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	iAF987.Gmet_2300	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
k59_218823_1	443144.GM21_0874	9.96e-07	55.8	2EUXR@1|root,33ND1@2|Bacteria,1P0HH@1224|Proteobacteria,431FA@68525|delta/epsilon subdivisions,2WWMS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_195760_1	1158292.JPOE01000002_gene1657	9.46e-20	89.7	COG0123@1|root,COG0123@2|Bacteria,1MU7P@1224|Proteobacteria,2VIK8@28216|Betaproteobacteria,1KJ7N@119065|unclassified Burkholderiales	28216|Betaproteobacteria	BQ	histone deacetylase	hdaH	-	-	-	-	-	-	-	-	-	-	-	Hist_deacetyl
k59_60179_1	1203606.HMPREF1526_02193	1.48e-16	82.0	COG0465@1|root,COG0465@2|Bacteria,1TPTV@1239|Firmicutes,247WQ@186801|Clostridia,36DIC@31979|Clostridiaceae	186801|Clostridia	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
k59_21652_1	96561.Dole_0426	1.06e-133	400.0	COG3852@1|root,COG3852@2|Bacteria,1NTTH@1224|Proteobacteria,42MC9@68525|delta/epsilon subdivisions,2WIYS@28221|Deltaproteobacteria,2MHU3@213118|Desulfobacterales	28221|Deltaproteobacteria	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	2.7.13.3	ko:K07709	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,PAS_4,PAS_9,sCache_3_2
k59_211902_1	335543.Sfum_0068	9.4e-116	358.0	COG0480@1|root,COG0480@2|Bacteria,1R0V4@1224|Proteobacteria,42M1F@68525|delta/epsilon subdivisions,2WIYM@28221|Deltaproteobacteria,2MR6X@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	Elongation factor Tu domain 2	fusA-1	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
k59_37337_4	1121440.AUMA01000019_gene1744	1.32e-155	459.0	COG4373@1|root,COG4373@2|Bacteria,1N2KG@1224|Proteobacteria,42NZD@68525|delta/epsilon subdivisions,2WJWU@28221|Deltaproteobacteria,2M8CI@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Mu-like prophage FluMu protein gp28	-	-	-	-	-	-	-	-	-	-	-	-	Terminase_6
k59_37337_5	1123274.KB899418_gene2333	4.28e-107	338.0	COG4383@1|root,COG4383@2|Bacteria	2|Bacteria	L	Mu-like prophage protein gp29	gp29	-	-	-	-	-	-	-	-	-	-	-	DUF935
k59_180758_2	706587.Desti_4540	1.32e-82	246.0	COG1943@1|root,COG1943@2|Bacteria,1MX19@1224|Proteobacteria,43BHF@68525|delta/epsilon subdivisions,2WQUJ@28221|Deltaproteobacteria,2MSK6@213462|Syntrophobacterales	28221|Deltaproteobacteria	L	PFAM Transposase IS200 like	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
k59_165565_1	1265505.ATUG01000001_gene3174	3.96e-121	361.0	COG1042@1|root,COG1042@2|Bacteria,1R8Q6@1224|Proteobacteria,42NR2@68525|delta/epsilon subdivisions,2WM2A@28221|Deltaproteobacteria,2MN2C@213118|Desulfobacterales	28221|Deltaproteobacteria	C	CoA binding domain	-	-	-	-	-	-	-	-	-	-	-	-	CoA_binding_2,Succ_CoA_lig
k59_29026_1	1121405.dsmv_3464	4.96e-21	97.1	COG0457@1|root,COG0457@2|Bacteria,1MYB8@1224|Proteobacteria,42P5H@68525|delta/epsilon subdivisions,2WKAU@28221|Deltaproteobacteria,2MIEU@213118|Desulfobacterales	28221|Deltaproteobacteria	G	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_14,TPR_16,TPR_19,TPR_2,TPR_4,TPR_6,TPR_7,TPR_8
k59_21657_1	1121405.dsmv_1507	1.72e-110	331.0	COG0141@1|root,COG0141@2|Bacteria,1MUUF@1224|Proteobacteria,42M3R@68525|delta/epsilon subdivisions,2WJGT@28221|Deltaproteobacteria,2MICP@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine	hisD	GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.23	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01158,R01163,R03012	RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000	-	-	-	Histidinol_dh
k59_158542_1	1121396.KB893077_gene741	3.6e-40	145.0	COG2152@1|root,COG2152@2|Bacteria,1MX8M@1224|Proteobacteria,42YYU@68525|delta/epsilon subdivisions,2WU8G@28221|Deltaproteobacteria,2MN6U@213118|Desulfobacterales	28221|Deltaproteobacteria	G	Pfam:DUF377	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_130
k59_158542_2	926569.ANT_31340	8.7e-28	104.0	COG0724@1|root,COG0724@2|Bacteria,2G74A@200795|Chloroflexi	200795|Chloroflexi	S	PFAM RNP-1 like RNA-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
k59_5858_3	1122217.KB899566_gene516	3.75e-06	53.1	COG0358@1|root,COG0358@2|Bacteria,1TQ0X@1239|Firmicutes,4H2CM@909932|Negativicutes	909932|Negativicutes	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB_bind,Toprim_2,Toprim_N,zf-CHC2
k59_37346_1	1121405.dsmv_0392	3.54e-65	209.0	COG0394@1|root,COG0655@1|root,COG0394@2|Bacteria,COG0655@2|Bacteria,1NANP@1224|Proteobacteria,42Q16@68525|delta/epsilon subdivisions,2WIJ7@28221|Deltaproteobacteria,2MIC1@213118|Desulfobacterales	28221|Deltaproteobacteria	T	PFAM NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red,LMWPc
k59_128297_1	641491.DND132_0561	2.86e-104	308.0	COG0428@1|root,COG0428@2|Bacteria,1MWEZ@1224|Proteobacteria,42NT2@68525|delta/epsilon subdivisions,2WJM5@28221|Deltaproteobacteria,2M7VT@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	Mediates zinc uptake. May also transport other divalent cations	gufA	-	-	ko:K07238	-	-	-	-	ko00000,ko02000	2.A.5.5	-	-	Zip
k59_189306_1	643562.Daes_0913	5.17e-32	117.0	COG1186@1|root,COG1186@2|Bacteria,1RH75@1224|Proteobacteria,42UF8@68525|delta/epsilon subdivisions,2WR6W@28221|Deltaproteobacteria,2MBZF@213115|Desulfovibrionales	28221|Deltaproteobacteria	J	PFAM Class I peptide chain release factor	-	-	-	ko:K15034	-	-	-	-	ko00000,ko03012	-	-	-	RF-1
k59_29045_1	1210045.ALNP01000003_gene4386	6.46e-16	73.9	COG5470@1|root,COG5470@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF1330
k59_204118_1	1051646.VITU9109_13671	1.63e-80	253.0	COG1680@1|root,COG1680@2|Bacteria,1P3SQ@1224|Proteobacteria,1RRMI@1236|Gammaproteobacteria,1Y2N9@135623|Vibrionales	135623|Vibrionales	V	COG1680 Beta-lactamase class C and other penicillin binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
k59_136140_1	706587.Desti_3164	1.84e-65	217.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,42M5F@68525|delta/epsilon subdivisions,2WISF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	IQ	PFAM AMP-dependent synthetase and ligase	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
k59_234735_1	667014.Thein_0970	5.05e-122	363.0	COG0107@1|root,COG0118@1|root,COG0107@2|Bacteria,COG0118@2|Bacteria,2GGYN@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit	hisF	-	-	ko:K01663,ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase,His_biosynth
k59_128314_1	1121403.AUCV01000007_gene1244	1.71e-94	300.0	COG0466@1|root,COG0466@2|Bacteria,1MUV2@1224|Proteobacteria,42M9W@68525|delta/epsilon subdivisions,2WJ29@28221|Deltaproteobacteria,2MHRD@213118|Desulfobacterales	28221|Deltaproteobacteria	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	-	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
k59_51962_2	880072.Desac_0835	3.57e-52	173.0	COG1908@1|root,COG2512@1|root,COG1908@2|Bacteria,COG2512@2|Bacteria,1RCZY@1224|Proteobacteria,42TFE@68525|delta/epsilon subdivisions,2WPDR@28221|Deltaproteobacteria,2MRBM@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	PFAM methyl-viologen-reducing hydrogenase, delta subunit	-	-	-	-	-	-	-	-	-	-	-	-	FlpD
k59_218844_1	1082931.KKY_2644	5.62e-56	187.0	COG2358@1|root,COG2358@2|Bacteria,1R8QD@1224|Proteobacteria,2U7M9@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	TRAP transporter solute receptor TAXI family protein	-	-	-	ko:K07080	-	-	-	-	ko00000	-	-	-	NMT1_3
k59_5880_1	439235.Dalk_2844	3.02e-63	215.0	COG0210@1|root,COG0210@2|Bacteria,1MU0G@1224|Proteobacteria,42MKU@68525|delta/epsilon subdivisions,2WJR3@28221|Deltaproteobacteria,2MI3D@213118|Desulfobacterales	28221|Deltaproteobacteria	L	UvrD REP helicase	pcrA	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
k59_241505_1	485915.Dret_1034	1.17e-82	257.0	COG0282@1|root,COG0282@2|Bacteria,1MW61@1224|Proteobacteria,42MJA@68525|delta/epsilon subdivisions,2WJBJ@28221|Deltaproteobacteria,2M87P@213115|Desulfovibrionales	28221|Deltaproteobacteria	F	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction	ackA	-	2.7.2.1	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00315,R01353	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetate_kinase
k59_67095_1	477974.Daud_0472	1.19e-28	116.0	COG0787@1|root,COG0787@2|Bacteria,1TNYY@1239|Firmicutes,2480T@186801|Clostridia,260IY@186807|Peptococcaceae	186801|Clostridia	M	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	alr	-	5.1.1.1,5.1.1.18	ko:K01775,ko:K18348	ko00473,ko01100,ko01502,ko02020,map00473,map01100,map01502,map02020	M00652	R00401	RC00285	ko00000,ko00001,ko00002,ko01000,ko01011,ko01504	-	-	-	Ala_racemase_C,Ala_racemase_N
k59_128323_1	1121918.ARWE01000001_gene1241	6.69e-41	152.0	COG1295@1|root,COG1295@2|Bacteria,1QICW@1224|Proteobacteria,42MBW@68525|delta/epsilon subdivisions,2WK2Z@28221|Deltaproteobacteria,43SWT@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	PFAM ribonuclease BN	-	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Rrf2,Virul_fac_BrkB
k59_44283_1	1169144.KB910949_gene3579	5.37e-17	83.6	COG2186@1|root,COG2186@2|Bacteria,1V2TU@1239|Firmicutes,4HDHI@91061|Bacilli,1ZD1T@1386|Bacillus	91061|Bacilli	K	COG2186 Transcriptional regulators	yvfI	-	-	ko:K05799	-	-	-	-	ko00000,ko03000	-	-	-	FCD,GntR
k59_29070_1	1121405.dsmv_0704	2.68e-70	217.0	COG1596@1|root,COG1596@2|Bacteria,1N7GP@1224|Proteobacteria,42SP0@68525|delta/epsilon subdivisions,2WNYF@28221|Deltaproteobacteria,2MKDY@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Polysaccharide biosynthesis/export protein	-	-	-	ko:K01991	ko02026,map02026	-	-	-	ko00000,ko00001,ko02000	1.B.18	-	-	Poly_export,SLBB
k59_105675_1	926569.ANT_26970	1.52e-23	103.0	COG2010@1|root,COG2864@1|root,COG2010@2|Bacteria,COG2864@2|Bacteria	2|Bacteria	C	formate dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_c3_2,Ni_hydr_CYTB,PSCyt1
k59_136162_1	656024.FsymDg_0159	2.26e-47	164.0	COG2107@1|root,COG2107@2|Bacteria,2GJHY@201174|Actinobacteria,4EUYC@85013|Frankiales	201174|Actinobacteria	S	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnD	-	-	ko:K11785	ko00130,ko01110,map00130,map01110	-	R08589	RC02330	ko00000,ko00001,ko01000	-	-	-	VitK2_biosynth
k59_74994_2	56780.SYN_02895	3.66e-36	140.0	COG0457@1|root,COG1462@1|root,COG0457@2|Bacteria,COG1462@2|Bacteria,1N4V4@1224|Proteobacteria,42WHI@68525|delta/epsilon subdivisions,2WRYH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Curli production assembly/transport component CsgG	-	-	-	-	-	-	-	-	-	-	-	-	CsgG
k59_44291_1	96561.Dole_1366	1.47e-36	135.0	COG0631@1|root,COG0631@2|Bacteria,1R7UF@1224|Proteobacteria,42QUA@68525|delta/epsilon subdivisions,2WP2A@28221|Deltaproteobacteria,2MJYX@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Serine/threonine phosphatases, family 2C, catalytic domain	-	-	3.1.3.16	ko:K01090,ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C,PP2C_2
k59_5891_1	1121405.dsmv_0014	5.87e-85	282.0	COG0574@1|root,COG0784@1|root,COG0574@2|Bacteria,COG0784@2|Bacteria,1N38V@1224|Proteobacteria,42MWC@68525|delta/epsilon subdivisions,2WKAZ@28221|Deltaproteobacteria,2MICZ@213118|Desulfobacterales	28221|Deltaproteobacteria	GT	pyruvate phosphate dikinase	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_2,PPDK_N
k59_82866_1	407392.A0MN47_9CAUD	1.71e-34	125.0	4QENJ@10239|Viruses,4QWTV@35237|dsDNA viruses  no RNA stage,4QPGY@28883|Caudovirales,4QI8E@10662|Myoviridae	10662|Myoviridae	S	methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_60228_1	933262.AXAM01000040_gene1215	3.51e-79	241.0	COG0241@1|root,COG0241@2|Bacteria,1RDGR@1224|Proteobacteria,42SCB@68525|delta/epsilon subdivisions,2WPEA@28221|Deltaproteobacteria,2MJSF@213118|Desulfobacterales	28221|Deltaproteobacteria	E	D,D-heptose 1,7-bisphosphate phosphatase	-	-	3.1.3.82,3.1.3.83	ko:K03273	ko00540,ko01100,map00540,map01100	M00064	R05647,R09771	RC00017	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hydrolase_like
k59_189337_1	225937.HP15_424	4.4e-17	89.0	COG3210@1|root,COG5306@1|root,COG3210@2|Bacteria,COG5306@2|Bacteria,1R4VM@1224|Proteobacteria,1RQVY@1236|Gammaproteobacteria,46D54@72275|Alteromonadaceae	1236|Gammaproteobacteria	U	Belongs to the peptidase S8 family	mshQ	-	-	ko:K12287	-	-	-	-	ko00000,ko02044	-	-	-	Bactofilin,Laminin_G_3,PA14
k59_113168_1	879212.DespoDRAFT_00791	9.52e-44	151.0	COG0500@1|root,COG0500@2|Bacteria,1RGJU@1224|Proteobacteria,42RZT@68525|delta/epsilon subdivisions,2WNDA@28221|Deltaproteobacteria,2MK15@213118|Desulfobacterales	28221|Deltaproteobacteria	Q	Tellurite resistance protein TehB	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31,Ubie_methyltran
k59_113168_2	177437.HRM2_41010	2.39e-27	110.0	COG0369@1|root,COG1151@2|Bacteria,1NYH2@1224|Proteobacteria,42NE1@68525|delta/epsilon subdivisions,2WIVX@28221|Deltaproteobacteria,2MINQ@213118|Desulfobacterales	28221|Deltaproteobacteria	C	TIGRFAM carbon-monoxide dehydrogenase, catalytic subunit	-	-	1.2.7.4	ko:K00198	ko00633,ko00680,ko00720,ko01120,ko01200,map00633,map00680,map00720,map01120,map01200	M00377	R07157,R08034	RC00250,RC02800	ko00000,ko00001,ko00002,ko01000	-	-	-	Prismane
k59_29081_1	1033739.CAEU01000040_gene833	1.26e-72	231.0	COG0444@1|root,COG0444@2|Bacteria,1TP6E@1239|Firmicutes,4HA4E@91061|Bacilli,26DTQ@186818|Planococcaceae	91061|Bacilli	EP	Oligopeptide/dipeptide transporter, C-terminal region	dppD	-	-	ko:K16202	ko02010,map02010	M00566	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.2	-	-	ABC_tran,oligo_HPY
k59_29081_2	935845.JADQ01000035_gene2204	1.4e-22	95.9	COG4608@1|root,COG4608@2|Bacteria,1V36J@1239|Firmicutes,4H9YB@91061|Bacilli,26QEH@186822|Paenibacillaceae	91061|Bacilli	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
k59_165609_1	706587.Desti_0873	3.17e-69	228.0	COG0633@1|root,COG3894@1|root,COG0633@2|Bacteria,COG3894@2|Bacteria,1MV6C@1224|Proteobacteria,42MF5@68525|delta/epsilon subdivisions,2WKC6@28221|Deltaproteobacteria,2MQU1@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	PFAM 2Fe-2S iron-sulfur cluster binding domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4445,Fer2
k59_60238_1	237368.SCABRO_02137	8.96e-119	361.0	COG0644@1|root,COG0644@2|Bacteria	2|Bacteria	C	geranylgeranyl reductase activity	prnA	-	1.14.19.9	ko:K14266	ko00404,ko01130,map00404,map01130	M00789,M00790	R09570	RC00949	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_halogenase
k59_5900_2	289376.THEYE_A1071	5.95e-08	59.7	COG1426@1|root,COG1426@2|Bacteria,3J1CJ@40117|Nitrospirae	40117|Nitrospirae	S	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4115,HTH_25
k59_97731_1	388413.ALPR1_14929	6.69e-51	179.0	COG3547@1|root,COG3547@2|Bacteria,4NIKY@976|Bacteroidetes	976|Bacteroidetes	L	Transposase IS116 IS110 IS902	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_51990_1	1121405.dsmv_3800	5.35e-115	343.0	COG0517@1|root,COG0517@2|Bacteria,1MXI6@1224|Proteobacteria,42SSD@68525|delta/epsilon subdivisions,2WPWR@28221|Deltaproteobacteria,2MK6M@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Putative transposase	-	-	-	-	-	-	-	-	-	-	-	-	Y2_Tnp,Zn_Tnp_IS91
k59_44305_1	439235.Dalk_0092	2.21e-25	112.0	COG1413@1|root,COG2199@1|root,COG3899@1|root,COG1413@2|Bacteria,COG2199@2|Bacteria,COG3899@2|Bacteria	2|Bacteria	T	PFAM Protein kinase domain	cpeY	-	2.7.11.1,2.7.7.65	ko:K05385,ko:K12132,ko:K13590	ko00196,ko01100,ko04112,map00196,map01100,map04112	-	-	-	ko00000,ko00001,ko00194,ko01000,ko01001	-	-	-	AAA_16,EAL,GGDEF,Trans_reg_C
k59_6343_2	1123257.AUFV01000013_gene2787	5.83e-08	57.4	COG2369@1|root,COG2369@2|Bacteria,1R40R@1224|Proteobacteria,1RPEA@1236|Gammaproteobacteria,1X8PF@135614|Xanthomonadales	135614|Xanthomonadales	S	Phage Mu protein F like protein	-	-	-	-	-	-	-	-	-	-	-	-	Phage_Mu_F
k59_159046_1	1415775.U729_1463	1.17e-11	65.9	COG1024@1|root,COG1024@2|Bacteria,1TQ89@1239|Firmicutes,247RK@186801|Clostridia,36EDS@31979|Clostridiaceae	186801|Clostridia	I	Belongs to the enoyl-CoA hydratase isomerase family	crt	-	4.2.1.17	ko:K01715	ko00650,ko01200,map00650,map01200	-	R03026	RC00831	ko00000,ko00001,ko01000	-	-	-	ECH_1
k59_159046_2	706587.Desti_0219	2.29e-55	189.0	COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,42P0M@68525|delta/epsilon subdivisions,2WJMC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	PFAM AMP-dependent synthetase and ligase	-	-	6.2.1.1,6.2.1.32	ko:K01895,ko:K08295	ko00010,ko00620,ko00627,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00627,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R00982,R01354	RC00004,RC00012,RC00043,RC00070,RC00174,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
k59_75452_2	457398.HMPREF0326_00962	7.31e-16	77.4	COG2414@1|root,COG2414@2|Bacteria,1MWBB@1224|Proteobacteria,42MZJ@68525|delta/epsilon subdivisions,2WJK1@28221|Deltaproteobacteria,2M804@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	PFAM Aldehyde ferredoxin oxidoreductase	-	-	1.2.7.5	ko:K03738	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00309	R08571	RC00242	ko00000,ko00001,ko00002,ko01000	-	-	-	AFOR_C,AFOR_N
k59_83372_1	56780.SYN_02361	6.6e-45	166.0	COG2203@1|root,COG2206@1|root,COG2203@2|Bacteria,COG2206@2|Bacteria,1MV37@1224|Proteobacteria,42N4N@68525|delta/epsilon subdivisions,2WKJ1@28221|Deltaproteobacteria,2MRBJ@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HD,HD_5
k59_83372_2	335543.Sfum_2138	1.72e-48	158.0	2D7FD@1|root,32TNY@2|Bacteria,1NAHU@1224|Proteobacteria,42VAC@68525|delta/epsilon subdivisions,2WR6Q@28221|Deltaproteobacteria,2MS75@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF1992)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1992
k59_98214_1	1158165.KB898874_gene1632	2.52e-37	139.0	COG0614@1|root,COG0614@2|Bacteria,1MWVF@1224|Proteobacteria,1RMV8@1236|Gammaproteobacteria,1WZG8@135613|Chromatiales	135613|Chromatiales	P	PFAM periplasmic binding protein	-	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
k59_128845_1	1033810.HLPCO_002883	0.00059	49.3	COG0438@1|root,COG1216@1|root,COG0438@2|Bacteria,COG1216@2|Bacteria,2NPQ4@2323|unclassified Bacteria	2|Bacteria	J	Glycosyltransferase like family 2	-	-	-	ko:K20444	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.1.3	GT2,GT4	-	DUF616,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1,Glycos_transf_2
k59_90939_1	879212.DespoDRAFT_00444	2.19e-18	78.6	COG1826@1|root,COG1826@2|Bacteria,1NGDP@1224|Proteobacteria,42V5P@68525|delta/epsilon subdivisions,2WRM0@28221|Deltaproteobacteria,2MKX6@213118|Desulfobacterales	28221|Deltaproteobacteria	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system	tatA	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
k59_52539_1	1121403.AUCV01000026_gene2383	4.81e-43	150.0	2C1E0@1|root,32R8I@2|Bacteria,1MY6R@1224|Proteobacteria,42SJH@68525|delta/epsilon subdivisions,2WPST@28221|Deltaproteobacteria,2MKD2@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_67611_1	247490.KSU1_C0840	1.21e-20	90.1	COG2010@1|root,COG2010@2|Bacteria,2IZC1@203682|Planctomycetes	203682|Planctomycetes	C	cytochrome C	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrome_CBB3
k59_196266_1	192952.MM_0695	8.98e-22	100.0	COG1782@1|root,arCOG00543@2157|Archaea,2XTIM@28890|Euryarchaeota,2N99U@224756|Methanomicrobia	224756|Methanomicrobia	S	KH, type 1, domain	-	-	-	ko:K07041	-	-	-	-	ko00000	-	-	-	Beta-Casp,KH_2,KH_7,Lactamase_B,Lactamase_B_6,RMMBL
k59_44798_1	1121405.dsmv_2773	2.66e-85	261.0	COG0196@1|root,COG0196@2|Bacteria,1MV9I@1224|Proteobacteria,42MV7@68525|delta/epsilon subdivisions,2WJTU@28221|Deltaproteobacteria,2MHYE@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Belongs to the ribF family	ribF	-	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
k59_98227_1	574376.BAMA_06515	8.47e-77	238.0	COG1024@1|root,COG1024@2|Bacteria,1TQ89@1239|Firmicutes,4HCH3@91061|Bacilli,1ZAXG@1386|Bacillus	91061|Bacilli	I	Belongs to the enoyl-CoA hydratase isomerase family	yngF	GO:0003674,GO:0003824,GO:0004300,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575	-	-	-	-	-	-	-	-	-	-	ECH_1
k59_150893_1	1382306.JNIM01000001_gene902	3.87e-64	213.0	COG0297@1|root,COG0297@2|Bacteria,2GA6I@200795|Chloroflexi	200795|Chloroflexi	G	Glycosyltransferase Family 4	-	-	2.4.1.250	ko:K15521	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_transf_4,Glycos_transf_1
k59_150893_2	525909.Afer_0264	2.83e-07	51.2	COG2120@1|root,COG2120@2|Bacteria,2GMVD@201174|Actinobacteria,4CMYW@84992|Acidimicrobiia	84992|Acidimicrobiia	S	GlcNAc-PI de-N-acetylase	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
k59_29589_1	1121440.AUMA01000003_gene3114	8.13e-63	209.0	COG1148@1|root,COG1148@2|Bacteria,1QUMN@1224|Proteobacteria,43BMA@68525|delta/epsilon subdivisions,2X6ZG@28221|Deltaproteobacteria,2M898@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	4Fe-4S ferredoxin iron-sulfur binding domain protein	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,FlpD,Pyr_redox_2
k59_44807_1	1121405.dsmv_2694	3.22e-23	99.0	COG1042@1|root,COG1042@2|Bacteria,1NU6B@1224|Proteobacteria,42NAU@68525|delta/epsilon subdivisions,2WJHX@28221|Deltaproteobacteria,2MIMR@213118|Desulfobacterales	28221|Deltaproteobacteria	C	ATP-grasp domain	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_5,CoA_binding_2,Succ_CoA_lig
k59_241943_2	880071.Fleli_1928	7.09e-32	124.0	COG3335@1|root,COG3415@1|root,COG3335@2|Bacteria,COG3415@2|Bacteria,4NKPG@976|Bacteroidetes,47TCB@768503|Cytophagia	976|Bacteroidetes	L	Winged helix-turn helix	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,HTH_29,HTH_33
k59_166047_1	638301.HMPREF0444_0689	0.000486	48.5	COG0500@1|root,COG2226@2|Bacteria,1TQUF@1239|Firmicutes,4HD2W@91061|Bacilli,27I3R@186828|Carnobacteriaceae	91061|Bacilli	Q	Nodulation protein S (NodS)	yqeM	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
k59_159076_2	1121468.AUBR01000010_gene2458	2.57e-82	247.0	COG0066@1|root,COG0066@2|Bacteria,1V1I6@1239|Firmicutes,24FUI@186801|Clostridia,42G3R@68295|Thermoanaerobacterales	186801|Clostridia	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuD	-	4.2.1.33,4.2.1.35	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R10170	RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase_C
k59_159076_3	909663.KI867149_gene3417	2.36e-08	54.7	COG0473@1|root,COG0473@2|Bacteria,1MUH4@1224|Proteobacteria,42M8G@68525|delta/epsilon subdivisions,2WIYB@28221|Deltaproteobacteria,2MR26@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	PFAM isocitrate isopropylmalate dehydrogenase	-	-	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
k59_44816_1	593117.TGAM_1771	2.26e-61	207.0	COG1274@1|root,arCOG05865@2157|Archaea,2XUU1@28890|Euryarchaeota,24380@183968|Thermococci	183968|Thermococci	C	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle	pckG	-	4.1.1.32	ko:K01596	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko03320,ko04068,ko04151,ko04152,ko04910,ko04920,ko04922,ko04931,ko04964,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map03320,map04068,map04151,map04152,map04910,map04920,map04922,map04931,map04964	M00003	R00431,R00726	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPCK_C,PEPCK_N
k59_128861_1	1132442.KB889752_gene1967	8.2e-08	60.1	COG3284@1|root,COG3852@1|root,COG5002@1|root,COG3284@2|Bacteria,COG3852@2|Bacteria,COG5002@2|Bacteria,1TRH0@1239|Firmicutes,4HD4A@91061|Bacilli,1ZARI@1386|Bacillus	91061|Bacilli	T	COG0642 Signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,MASE3,PAS,PAS_3,PAS_4,PAS_9
k59_166052_1	1168034.FH5T_04065	5.56e-39	144.0	COG3547@1|root,COG3547@2|Bacteria,4NHYP@976|Bacteroidetes,2FKYS@200643|Bacteroidia	976|Bacteroidetes	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_90969_1	1121405.dsmv_1751	1.61e-94	284.0	COG0559@1|root,COG0559@2|Bacteria,1MU25@1224|Proteobacteria,42N64@68525|delta/epsilon subdivisions,2WJ73@28221|Deltaproteobacteria,2MIX5@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Branched-chain amino acid transport system / permease component	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
k59_6372_1	1121406.JAEX01000005_gene2997	1.05e-58	197.0	COG1226@1|root,COG1226@2|Bacteria,1MU1R@1224|Proteobacteria,42MW6@68525|delta/epsilon subdivisions,2WIYU@28221|Deltaproteobacteria,2M9CJ@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	Ion transport 2 domain protein	-	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans_2,TrkA_C,TrkA_N
k59_219354_1	880072.Desac_0388	2.74e-53	183.0	COG2203@1|root,COG2206@1|root,COG3437@1|root,COG2203@2|Bacteria,COG2206@2|Bacteria,COG3437@2|Bacteria,1MV37@1224|Proteobacteria,42N4N@68525|delta/epsilon subdivisions,2WKJ1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	metal-dependent phosphohydrolase HD region	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HD,HD_5
k59_67634_1	1121405.dsmv_3392	4.67e-21	87.8	COG4657@1|root,COG4657@2|Bacteria,1MU8X@1224|Proteobacteria,42MCM@68525|delta/epsilon subdivisions,2WKRE@28221|Deltaproteobacteria,2MJ7J@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Part of a membrane complex involved in electron transport	rnfA	-	-	ko:K03617	-	-	-	-	ko00000	-	-	-	Rnf-Nqr
k59_67634_2	1121456.ATVA01000015_gene2331	6.92e-90	270.0	COG4660@1|root,COG4660@2|Bacteria,1MW6N@1224|Proteobacteria,42NVB@68525|delta/epsilon subdivisions,2WK6R@28221|Deltaproteobacteria,2M88C@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	Part of a membrane complex involved in electron transport	rnfE	-	-	ko:K03613	-	-	-	-	ko00000	-	-	-	Rnf-Nqr
k59_121178_1	338966.Ppro_3013	4.18e-40	151.0	COG1530@1|root,COG3170@1|root,COG1530@2|Bacteria,COG3170@2|Bacteria,1MV65@1224|Proteobacteria,42M5E@68525|delta/epsilon subdivisions,2WIV6@28221|Deltaproteobacteria,43T1R@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs	rne	-	3.1.26.12	ko:K08300,ko:K08301	ko03018,map03018	M00394	-	-	ko00000,ko00001,ko00002,ko01000,ko03009,ko03019	-	-	-	RNase_E_G,S1
k59_196301_1	1249627.D779_3882	3.16e-46	166.0	COG0659@1|root,COG0659@2|Bacteria,1MWDF@1224|Proteobacteria,1SYC8@1236|Gammaproteobacteria,1WWSA@135613|Chromatiales	135613|Chromatiales	U	sulphate transporter	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
k59_196301_2	868131.MSWAN_1839	5.74e-05	45.1	COG1926@1|root,arCOG00041@2157|Archaea,2XWHP@28890|Euryarchaeota	28890|Euryarchaeota	F	phosphoribosyltransferases	prt	-	-	-	-	-	-	-	-	-	-	-	Pribosyltran
k59_29624_1	335543.Sfum_3459	3.03e-69	221.0	COG1309@1|root,COG1309@2|Bacteria,1Q299@1224|Proteobacteria,42UP4@68525|delta/epsilon subdivisions,2WQF0@28221|Deltaproteobacteria,2MS2K@213462|Syntrophobacterales	28221|Deltaproteobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
k59_29624_2	696369.KI912183_gene876	4.66e-24	93.6	COG0236@1|root,COG0236@2|Bacteria,1VEE3@1239|Firmicutes,24QME@186801|Clostridia,262SV@186807|Peptococcaceae	186801|Clostridia	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
k59_174089_1	96561.Dole_0595	3.23e-14	72.8	COG0768@1|root,COG0768@2|Bacteria,1MV8C@1224|Proteobacteria,42M1S@68525|delta/epsilon subdivisions,2WJ02@28221|Deltaproteobacteria,2MHV4@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Penicillin-binding Protein dimerisation domain	mrdA	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	iAF987.Gmet_0928	PBP_dimer,Transpeptidase
k59_174089_2	177437.HRM2_35250	2.93e-14	74.3	2BW94@1|root,32VZD@2|Bacteria,1N1VY@1224|Proteobacteria,42TZS@68525|delta/epsilon subdivisions,2WQZ0@28221|Deltaproteobacteria,2MKNQ@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	ko:K03571	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	-
k59_174089_3	933262.AXAM01000010_gene1379	0.000539	42.4	COG1792@1|root,COG1792@2|Bacteria,1N8ZS@1224|Proteobacteria,42S9I@68525|delta/epsilon subdivisions,2WNTW@28221|Deltaproteobacteria,2MJMG@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Involved in formation and maintenance of cell shape	mreC	-	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
k59_159104_1	439235.Dalk_0047	1.56e-55	189.0	COG2239@1|root,COG2239@2|Bacteria,1MW24@1224|Proteobacteria,42MA7@68525|delta/epsilon subdivisions,2WIPC@28221|Deltaproteobacteria,2MI8B@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Acts as a magnesium transporter	-	-	-	ko:K06213	-	-	-	-	ko00000,ko02000	1.A.26.1	-	-	CBS,MgtE,MgtE_N
k59_150933_1	457398.HMPREF0326_01088	0.000239	43.9	COG3551@1|root,COG3551@2|Bacteria,1RB2G@1224|Proteobacteria,42UMV@68525|delta/epsilon subdivisions,2WR43@28221|Deltaproteobacteria,2MDHR@213115|Desulfovibrionales	28221|Deltaproteobacteria	J	Sulfotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_150933_3	1211777.BN77_4166	3.89e-47	176.0	COG3170@1|root,COG3170@2|Bacteria,1QVEE@1224|Proteobacteria,2TWDG@28211|Alphaproteobacteria,4BHSG@82115|Rhizobiaceae	28211|Alphaproteobacteria	NU	Phage P22-like portal protein	-	-	-	-	-	-	-	-	-	-	-	-	P22_portal
k59_67656_1	439235.Dalk_4262	8.01e-35	136.0	COG0664@1|root,COG1033@1|root,COG2199@1|root,COG0664@2|Bacteria,COG1033@2|Bacteria,COG3706@2|Bacteria,1MUE1@1224|Proteobacteria,42ME2@68525|delta/epsilon subdivisions,2WJRI@28221|Deltaproteobacteria,2MJQ7@213118|Desulfobacterales	28221|Deltaproteobacteria	K	MMPL family	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	GGDEF,LolA_like,MMPL,cNMP_binding
k59_150934_1	1121007.AUML01000095_gene1103	1.39e-101	307.0	COG3547@1|root,COG3547@2|Bacteria,4NGED@976|Bacteroidetes,1HYRZ@117743|Flavobacteriia	976|Bacteroidetes	L	PFAM Transposase IS116 IS110 IS902 family	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_181263_1	667014.Thein_1827	3.05e-52	186.0	COG0495@1|root,COG0495@2|Bacteria,2GGX2@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	-	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1
k59_166087_2	1121918.ARWE01000001_gene3254	7.62e-181	513.0	COG3547@1|root,COG3547@2|Bacteria,1MUER@1224|Proteobacteria,42WT2@68525|delta/epsilon subdivisions,2WR9X@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	transposase IS116 IS110 IS902 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_29653_1	335543.Sfum_1590	1.94e-66	217.0	COG0373@1|root,COG0373@2|Bacteria,1MU41@1224|Proteobacteria,42MUG@68525|delta/epsilon subdivisions,2WISB@28221|Deltaproteobacteria,2MR5R@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,GlutR_dimer,Shikimate_DH
k59_227037_1	335543.Sfum_2759	7.89e-103	310.0	COG0151@1|root,COG0151@2|Bacteria,1MUAH@1224|Proteobacteria,42MCI@68525|delta/epsilon subdivisions,2WJ7H@28221|Deltaproteobacteria,2MQ82@213462|Syntrophobacterales	28221|Deltaproteobacteria	F	Phosphoribosylglycinamide synthetase, C domain	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC,GARS_A,GARS_C,GARS_N
k59_44852_1	933262.AXAM01000034_gene1559	1.86e-81	261.0	COG0664@1|root,COG0664@2|Bacteria,1R8R8@1224|Proteobacteria,42PH6@68525|delta/epsilon subdivisions,2WKQJ@28221|Deltaproteobacteria,2MJ5X@213118|Desulfobacterales	28221|Deltaproteobacteria	T	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_67673_1	1121413.JMKT01000002_gene2647	9.06e-29	115.0	COG3581@1|root,COG3581@2|Bacteria,1N1N8@1224|Proteobacteria,42UB7@68525|delta/epsilon subdivisions,2WQ9V@28221|Deltaproteobacteria,2MHJM@213115|Desulfovibrionales	28221|Deltaproteobacteria	I	4 iron, 4 sulfur cluster binding	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_67673_2	555779.Dthio_PD1799	2.14e-58	204.0	COG1924@1|root,COG3580@1|root,COG1924@2|Bacteria,COG3580@2|Bacteria,1PKG6@1224|Proteobacteria,42MY4@68525|delta/epsilon subdivisions,2WJFI@28221|Deltaproteobacteria,2M8T9@213115|Desulfovibrionales	28221|Deltaproteobacteria	I	ATPase BadF BadG BcrA BcrD type	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG,DUF2229
k59_29669_1	243232.MJ_0499	4.96e-75	238.0	COG0065@1|root,arCOG01698@2157|Archaea,2XTWH@28890|Euryarchaeota,23QNF@183939|Methanococci	183939|Methanococci	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuC	-	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase
k59_196353_1	1150474.JQJI01000023_gene777	8.43e-05	43.5	COG1586@1|root,COG1586@2|Bacteria,2GCWX@200918|Thermotogae	200918|Thermotogae	F	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine	speH	-	4.1.1.50	ko:K01611	ko00270,ko00330,ko01100,map00270,map00330,map01100	M00034,M00133	R00178	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	AdoMet_dc
k59_98310_1	1121403.AUCV01000042_gene127	4.07e-33	127.0	COG4972@1|root,COG4972@2|Bacteria,1MX8P@1224|Proteobacteria,42M36@68525|delta/epsilon subdivisions,2WJFJ@28221|Deltaproteobacteria,2MID0@213118|Desulfobacterales	28221|Deltaproteobacteria	NU	TIGRFAM type IV pilus assembly protein PilM	pilM	-	-	ko:K02662	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilM_2
k59_52606_1	335543.Sfum_3299	7.47e-79	249.0	COG0141@1|root,COG0141@2|Bacteria,1MUUF@1224|Proteobacteria,42M3R@68525|delta/epsilon subdivisions,2WJGT@28221|Deltaproteobacteria,2MQCY@213462|Syntrophobacterales	28221|Deltaproteobacteria	E	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine	hisD	GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.23	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01158,R01163,R03012	RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000	-	-	-	Histidinol_dh
k59_227053_1	880072.Desac_1832	6.73e-35	135.0	COG0147@1|root,COG0147@2|Bacteria,1MVBJ@1224|Proteobacteria,42MXN@68525|delta/epsilon subdivisions,2WJN0@28221|Deltaproteobacteria,2MQ88@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia	trpE	-	4.1.3.27	ko:K01657,ko:K13503	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
k59_181297_1	335543.Sfum_0356	8.62e-163	471.0	COG0129@1|root,COG0129@2|Bacteria,1MUTQ@1224|Proteobacteria,42N3P@68525|delta/epsilon subdivisions,2WJB7@28221|Deltaproteobacteria,2MQ9M@213462|Syntrophobacterales	28221|Deltaproteobacteria	EG	Belongs to the IlvD Edd family	ilvD	-	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1259	ILVD_EDD
k59_166123_1	1500304.JQKY01000008_gene3092	7.39e-37	143.0	COG0457@1|root,COG2114@1|root,COG5616@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,2TRUI@28211|Alphaproteobacteria,4B9BA@82115|Rhizobiaceae	28211|Alphaproteobacteria	T	Adenylate cyclase	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc,TPR_16,TPR_19,TPR_2,TPR_8
k59_22204_1	335543.Sfum_0192	3.02e-133	404.0	COG0525@1|root,COG0525@2|Bacteria,1MV7B@1224|Proteobacteria,42MPZ@68525|delta/epsilon subdivisions,2WIR9@28221|Deltaproteobacteria,2MQ5P@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
k59_189775_1	1196095.GAPWK_0765	2.9e-07	54.7	COG1088@1|root,COG1088@2|Bacteria,1MU5E@1224|Proteobacteria,1RP7G@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily	rfbB	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
k59_189775_4	1400524.KL370779_gene627	3.89e-07	53.5	COG0451@1|root,COG0451@2|Bacteria,1MUGT@1224|Proteobacteria,2TRF6@28211|Alphaproteobacteria,4BPUX@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	GM	Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction	-	-	1.1.1.271	ko:K02377	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R05692	RC01014	ko00000,ko00001,ko01000	-	-	-	Epimerase
k59_189777_1	1499967.BAYZ01000123_gene2538	1.46e-63	200.0	COG0778@1|root,COG0778@2|Bacteria	2|Bacteria	C	coenzyme F420-1:gamma-L-glutamate ligase activity	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
k59_60957_1	1121396.KB892990_gene4471	1.3e-82	258.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WJKZ@28221|Deltaproteobacteria,2MHUG@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Bacterial regulatory protein, Fis family	-	-	-	ko:K07713	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
k59_103372_1	1123247.AUIJ01000008_gene2600	1.23e-47	165.0	COG1879@1|root,COG1879@2|Bacteria,1MXQN@1224|Proteobacteria,2TTR1@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	COG1879 ABC-type sugar transport system periplasmic component	torT	-	-	ko:K10439,ko:K11930	ko02010,ko02030,map02010,map02030	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	Peripla_BP_1,Peripla_BP_4
k59_141373_1	222984.JNCS01000004_gene2607	7.55e-53	180.0	COG0075@1|root,arCOG00082@2157|Archaea,2XTWU@28890|Euryarchaeota,23STX@183963|Halobacteria	183963|Halobacteria	E	Serine-pyruvate aminotransferase archaeal aspartate aminotransferase	agxT	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
k59_49909_1	879212.DespoDRAFT_02827	8.81e-154	446.0	COG4584@1|root,COG4584@2|Bacteria,1MW5J@1224|Proteobacteria,42X93@68525|delta/epsilon subdivisions,2WSXR@28221|Deltaproteobacteria,2MQ06@213118|Desulfobacterales	28221|Deltaproteobacteria	L	PFAM Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	rve
k59_156528_1	666684.AfiDRAFT_2897	9.84e-13	74.3	COG2041@1|root,COG2041@2|Bacteria,1MX9E@1224|Proteobacteria,2TRK0@28211|Alphaproteobacteria,3JRNN@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Mo-co oxidoreductase dimerisation domain	MA20_04585	-	-	-	-	-	-	-	-	-	-	-	Mo-co_dimer,Oxidored_molyb
k59_187043_1	1323663.AROI01000031_gene1936	1.45e-06	55.8	COG2199@1|root,COG2199@2|Bacteria,1RGCV@1224|Proteobacteria	1224|Proteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE4,DUF1631,EAL,GGDEF,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
k59_209638_1	795359.TOPB45_0633	9.01e-36	141.0	COG0045@1|root,COG1042@1|root,COG0045@2|Bacteria,COG1042@2|Bacteria,2GH97@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	C	Succinyl-CoA ligase like flavodoxin domain	-	-	6.2.1.13	ko:K01905,ko:K22224	ko00010,ko00620,ko00640,ko01100,ko01120,map00010,map00620,map00640,map01100,map01120	-	R00229,R00920	RC00004,RC00012,RC00014	ko00000,ko00001,ko01000,ko01004	-	-	-	ATP-grasp_5,CoA_binding_2,Succ_CoA_lig
k59_19568_1	1121405.dsmv_3234	1.93e-121	365.0	COG0143@1|root,COG0143@2|Bacteria,1MUBY@1224|Proteobacteria,42N1K@68525|delta/epsilon subdivisions,2WIT6@28221|Deltaproteobacteria,2MHP4@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	-	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g,tRNA_bind
k59_163530_1	1506994.JNLQ01000002_gene1544	2.67e-08	60.5	COG0142@1|root,COG0142@2|Bacteria,1TPQY@1239|Firmicutes,248DE@186801|Clostridia,4BW2X@830|Butyrivibrio	186801|Clostridia	H	Polyprenyl synthetase	ispA	-	2.5.1.1,2.5.1.10,2.5.1.29	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00366	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	iHN637.CLJU_RS05465	polyprenyl_synt
k59_232525_1	329726.AM1_4874	1.14e-164	484.0	COG3039@1|root,COG3039@2|Bacteria,1G3YX@1117|Cyanobacteria	1117|Cyanobacteria	L	COG3039 Transposase and inactivated derivatives, IS5 family	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_2,DUF772
k59_103385_1	518766.Rmar_2513	2.29e-17	86.3	COG0557@1|root,COG0557@2|Bacteria,4NE7T@976|Bacteroidetes,1FIPN@1100069|Bacteroidetes Order II. Incertae sedis	2|Bacteria	K	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs	rnb	GO:0000175,GO:0000178,GO:0000932,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009056,GO:0009057,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0019439,GO:0022613,GO:0032991,GO:0034470,GO:0034641,GO:0034655,GO:0034660,GO:0035770,GO:0036464,GO:0042254,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1902494,GO:1905354,GO:1990904	3.1.13.1	ko:K01147	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RNB
k59_148170_1	879212.DespoDRAFT_01113	9.56e-71	228.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,2MI1N@213118|Desulfobacterales	28221|Deltaproteobacteria	T	sigma-54 factor interaction domain-containing protein	pilR	-	-	ko:K02667	ko02020,map02020	M00501	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	HTH_8,Response_reg,Sigma54_activat
k59_64966_1	56780.SYN_01757	2.55e-12	72.4	COG4966@1|root,COG4966@2|Bacteria,1Q8WE@1224|Proteobacteria,439J3@68525|delta/epsilon subdivisions,2X4VK@28221|Deltaproteobacteria,2MSHQ@213462|Syntrophobacterales	28221|Deltaproteobacteria	NU	Pfam:N_methyl_2	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
k59_73044_1	568768.CM001975_gene2305	2.38e-51	176.0	COG1783@1|root,COG1783@2|Bacteria,1R66A@1224|Proteobacteria,1RQFD@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Phage terminase, large subunit	-	-	-	ko:K06909	-	-	-	-	ko00000	-	-	-	Terminase_3,Terminase_3C
k59_171483_1	1121430.JMLG01000001_gene2251	7.55e-22	98.6	COG2239@1|root,COG2239@2|Bacteria,1TP4V@1239|Firmicutes,2481R@186801|Clostridia,260ZV@186807|Peptococcaceae	186801|Clostridia	P	transporter (mgtE)	mgtE	-	-	ko:K06213	-	-	-	-	ko00000,ko02000	1.A.26.1	-	-	CBS,MgtE,MgtE_N
k59_178544_1	1121912.AUHD01000026_gene310	7.58e-49	177.0	COG3344@1|root,COG3344@2|Bacteria,4NHMS@976|Bacteroidetes,1HZPH@117743|Flavobacteriia	976|Bacteroidetes	L	reverse transcriptase	-	-	-	-	-	-	-	-	-	-	-	-	GIIM,RVT_1
k59_126264_1	880073.Calab_2684	1.98e-38	142.0	COG1008@1|root,COG1008@2|Bacteria,2NNQ9@2323|unclassified Bacteria	2|Bacteria	C	NADH-quinone oxidoreductase, chain M	nuoM2	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q5_N,Proton_antipo_M
k59_117908_1	880072.Desac_1012	3.34e-44	153.0	COG5421@1|root,COG5421@2|Bacteria,1R3NX@1224|Proteobacteria,42QDV@68525|delta/epsilon subdivisions,2WIRQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	PFAM transposase, IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_232534_1	883.DvMF_0844	3.76e-29	113.0	COG0009@1|root,COG0009@2|Bacteria,1MVPM@1224|Proteobacteria,42UBZ@68525|delta/epsilon subdivisions,2WQ0E@28221|Deltaproteobacteria,2MA0Q@213115|Desulfovibrionales	28221|Deltaproteobacteria	J	Belongs to the SUA5 family	-	-	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	Sua5_yciO_yrdC
k59_133781_1	880072.Desac_1210	1.67e-104	319.0	COG1007@1|root,COG1007@2|Bacteria,1MV56@1224|Proteobacteria,42P7Z@68525|delta/epsilon subdivisions,2WKS0@28221|Deltaproteobacteria,2MQ9R@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
k59_19581_1	643473.KB235930_gene1670	2.09e-07	56.6	COG0642@1|root,COG0784@1|root,COG2199@1|root,COG2202@1|root,COG2203@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,COG3706@2|Bacteria,1G09B@1117|Cyanobacteria,1HJ8D@1161|Nostocales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	2.7.13.3	ko:K11527	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	GAF,GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
k59_163541_2	518766.Rmar_2315	2.28e-23	99.0	2E3CB@1|root,32YBM@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4154)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4154
k59_26928_1	101510.RHA1_ro01609	1.19e-78	244.0	COG3335@1|root,COG3335@2|Bacteria,2GJQI@201174|Actinobacteria,4FX98@85025|Nocardiaceae	201174|Actinobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,HTH_29
k59_35213_2	1121405.dsmv_0470	3.44e-25	104.0	COG1680@1|root,COG1680@2|Bacteria,1QUYZ@1224|Proteobacteria,42PUC@68525|delta/epsilon subdivisions,2WK0V@28221|Deltaproteobacteria,2MIWD@213118|Desulfobacterales	28221|Deltaproteobacteria	V	PFAM Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
k59_163548_2	1121035.AUCH01000005_gene78	1.6e-46	155.0	COG3157@1|root,COG3157@2|Bacteria,1RBTU@1224|Proteobacteria,2WEFR@28216|Betaproteobacteria,2M03R@206389|Rhodocyclales	206389|Rhodocyclales	S	This family consists of several bacterial proteins of	-	-	-	ko:K11903	ko02025,ko03070,map02025,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko02044	-	-	-	T6SS_HCP
k59_42127_1	324602.Caur_3235	5.29e-32	119.0	COG3677@1|root,COG3677@2|Bacteria	2|Bacteria	L	transposition, DNA-mediated	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS1595,HTH_23
k59_49928_1	1232410.KI421413_gene593	1.88e-88	269.0	COG0540@1|root,COG0540@2|Bacteria,1MWAB@1224|Proteobacteria,42NMR@68525|delta/epsilon subdivisions,2WJQR@28221|Deltaproteobacteria,43S21@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain	pyrB	GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
k59_171501_1	311424.DhcVS_792	1.27e-195	553.0	COG1900@1|root,COG1900@2|Bacteria,2GASV@200795|Chloroflexi,34DA0@301297|Dehalococcoidia	301297|Dehalococcoidia	S	Homocysteine biosynthesis enzyme, sulfur-incorporation	-	-	-	-	-	-	-	-	-	-	-	-	HcyBio
k59_171501_2	1140.Synpcc7942_2129	6.65e-22	91.7	COG1135@1|root,COG1145@1|root,COG1135@2|Bacteria,COG1145@2|Bacteria,1G5Q2@1117|Cyanobacteria,1H0I2@1129|Synechococcus	1117|Cyanobacteria	C	NIL	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,NIL
k59_163564_1	879308.HMPREF9130_0222	1.46e-20	89.4	COG1024@1|root,COG1024@2|Bacteria,1TQ89@1239|Firmicutes,247RK@186801|Clostridia,22H1B@1570339|Peptoniphilaceae	186801|Clostridia	I	Belongs to the enoyl-CoA hydratase isomerase family	crt	-	4.2.1.17	ko:K01715	ko00650,ko01200,map00650,map01200	-	R03026	RC00831	ko00000,ko00001,ko01000	-	-	-	ECH_1
k59_163564_2	335543.Sfum_1683	1.6e-26	106.0	COG1541@1|root,COG1541@2|Bacteria,1MV1W@1224|Proteobacteria,42NKD@68525|delta/epsilon subdivisions,2WIWV@28221|Deltaproteobacteria,2MR0M@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)	paaK-2	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	iAF987.Gmet_1825	AMP-binding,AMP-binding_C_2
k59_19597_1	1541960.KQ78_01213	8.38e-43	155.0	COG0272@1|root,COG0272@2|Bacteria	2|Bacteria	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligB	GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360,GO:1901576	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
k59_87917_1	1121405.dsmv_0791	6.99e-30	116.0	COG1651@1|root,COG1651@2|Bacteria,1RKYF@1224|Proteobacteria,42T64@68525|delta/epsilon subdivisions,2WP82@28221|Deltaproteobacteria,2MNDC@213118|Desulfobacterales	28221|Deltaproteobacteria	O	Thioredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_4
k59_57997_1	335543.Sfum_3207	1.91e-80	251.0	COG0115@1|root,COG0115@2|Bacteria,1MVB0@1224|Proteobacteria,42PRS@68525|delta/epsilon subdivisions,2WK0H@28221|Deltaproteobacteria	28221|Deltaproteobacteria	EH	PFAM aminotransferase, class IV	-	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
k59_178587_1	1121405.dsmv_0756	7.07e-102	301.0	COG0411@1|root,COG0411@2|Bacteria,1MUTY@1224|Proteobacteria,42NMG@68525|delta/epsilon subdivisions,2WJ48@28221|Deltaproteobacteria,2MITM@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Branched-chain amino acid ATP-binding cassette transporter	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
k59_141424_1	316067.Geob_0392	1.32e-99	315.0	COG0060@1|root,COG0060@2|Bacteria,1MVBQ@1224|Proteobacteria,42MKB@68525|delta/epsilon subdivisions,2WJ4W@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1,zf-FPG_IleRS
k59_95786_1	1449336.JQLO01000001_gene1160	6.89e-27	114.0	COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,4IS5F@91061|Bacilli	91061|Bacilli	T	Histidine kinase	hssS	-	2.7.13.3	ko:K02484	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
k59_156555_1	159749.K0SUR1	1.1e-13	76.6	2927D@1|root,2R93S@2759|Eukaryota,2XF3N@2836|Bacillariophyta	2836|Bacillariophyta	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2779
k59_141426_1	518766.Rmar_2140	1.71e-48	166.0	COG3676@1|root,COG3677@1|root,COG3676@2|Bacteria,COG3677@2|Bacteria,4NS7V@976|Bacteroidetes	976|Bacteroidetes	L	ISXO2-like transposase domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS1595,Zn_Tnp_IS1595
k59_141428_1	644282.Deba_2679	1.55e-63	210.0	COG1492@1|root,COG1492@2|Bacteria,1MUFY@1224|Proteobacteria,42M9K@68525|delta/epsilon subdivisions,2WJ22@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation	cobQ	-	6.3.5.10	ko:K02232	ko00860,ko01100,map00860,map01100	M00122	R05225	RC00010,RC01302	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_26,Aminotran_1_2,CbiA,GATase_3,TP_methylase
k59_95787_1	1121094.KB894648_gene471	2.68e-68	230.0	COG4584@1|root,COG4584@2|Bacteria,4NEY6@976|Bacteroidetes,2FMHY@200643|Bacteroidia,4APGX@815|Bacteroidaceae	976|Bacteroidetes	L	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	rve
k59_35252_2	1307759.JOMJ01000003_gene2099	5.53e-09	58.5	COG0451@1|root,COG0451@2|Bacteria,1MW32@1224|Proteobacteria,42NJT@68525|delta/epsilon subdivisions,2WM7E@28221|Deltaproteobacteria,2MAS7@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	NmrA-like family	dfrA	-	1.1.1.219	ko:K00091	-	-	-	-	ko00000,ko01000	-	-	-	3Beta_HSD,Epimerase
k59_118540_1	880072.Desac_1171	3.55e-98	294.0	COG1077@1|root,COG1077@2|Bacteria,1MUMW@1224|Proteobacteria,42M1J@68525|delta/epsilon subdivisions,2WIQR@28221|Deltaproteobacteria,2MQB1@213462|Syntrophobacterales	28221|Deltaproteobacteria	D	TIGRFAM cell shape determining protein, MreB Mrl family	mreB	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
k59_4443_1	1232437.KL662020_gene677	3.49e-81	270.0	COG0587@1|root,COG0587@2|Bacteria,1MUIF@1224|Proteobacteria,42MGP@68525|delta/epsilon subdivisions,2WIZ2@28221|Deltaproteobacteria,2MI79@213118|Desulfobacterales	28221|Deltaproteobacteria	L	DNA polymerase III alpha subunit	dnaE	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
k59_172190_1	472759.Nhal_0429	1.07e-58	187.0	COG2452@1|root,COG2452@2|Bacteria,1QV30@1224|Proteobacteria,1S2GA@1236|Gammaproteobacteria,1X285@135613|Chromatiales	1236|Gammaproteobacteria	K	regulatory protein, MerR	-	-	-	-	-	-	-	-	-	-	-	-	MerR,Resolvase
k59_111480_1	1121396.KB893035_gene3573	2.66e-27	108.0	COG0148@1|root,COG0148@2|Bacteria,1MU1N@1224|Proteobacteria,42MS9@68525|delta/epsilon subdivisions,2WJMS@28221|Deltaproteobacteria,2MI3S@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
k59_148763_1	1307761.L21SP2_2089	7.23e-64	217.0	COG3666@1|root,COG3666@2|Bacteria,2J98U@203691|Spirochaetes	203691|Spirochaetes	L	COG3666 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_6,DUF772
k59_202615_1	1265505.ATUG01000001_gene3658	5.54e-48	158.0	COG0440@1|root,COG0440@2|Bacteria,1RM73@1224|Proteobacteria,42SQI@68525|delta/epsilon subdivisions,2WPS2@28221|Deltaproteobacteria,2MK7U@213118|Desulfobacterales	28221|Deltaproteobacteria	E	ACT domain	-	-	-	-	-	-	-	-	-	-	-	-	ACT_5,ALS_ss_C
k59_194306_1	1121406.JAEX01000017_gene1908	2.93e-60	198.0	COG0697@1|root,COG0697@2|Bacteria,1PX5W@1224|Proteobacteria,42MGR@68525|delta/epsilon subdivisions,2WJSI@28221|Deltaproteobacteria,2M9Y0@213115|Desulfovibrionales	28221|Deltaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
k59_202620_1	177437.HRM2_44350	3.12e-26	111.0	COG4584@1|root,COG4584@2|Bacteria,1MWIV@1224|Proteobacteria,42MF0@68525|delta/epsilon subdivisions,2WMC1@28221|Deltaproteobacteria,2MIDP@213118|Desulfobacterales	28221|Deltaproteobacteria	L	Transposase for insertion sequences IS1326 IS1353 (IS21 IS408 IS1162 family protein)	-	-	-	-	-	-	-	-	-	-	-	-	rve
k59_13302_1	1214217.ALNF01000014_gene1390	2.26e-45	155.0	COG0863@1|root,COG0863@2|Bacteria	2|Bacteria	L	N-4 methylation of cytosine	-	-	2.1.1.72	ko:K00571	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	N6_N4_Mtase
k59_65552_1	290317.Cpha266_2139	9.58e-79	247.0	COG3335@1|root,COG3335@2|Bacteria	2|Bacteria	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,HTH_23,HTH_29,HTH_33
k59_104064_1	1432055.GLUCORHAEAF1_16515	5.47e-10	65.5	COG1807@1|root,COG1807@2|Bacteria,1NMIZ@1224|Proteobacteria,2TRS4@28211|Alphaproteobacteria,2JQTC@204441|Rhodospirillales	204441|Rhodospirillales	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT,PMT_2
k59_134507_1	1232437.KL662016_gene1052	1.64e-30	124.0	COG1529@1|root,COG1529@2|Bacteria,1MUEA@1224|Proteobacteria,42MER@68525|delta/epsilon subdivisions,2WIYV@28221|Deltaproteobacteria,2MJFX@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2,Fer2,Fer2_2
k59_217437_1	933262.AXAM01000062_gene948	1.86e-80	266.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2WJN5@28221|Deltaproteobacteria,2MIEI@213118|Desulfobacterales	28221|Deltaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_73648_1	96561.Dole_2792	6.02e-85	269.0	COG0769@1|root,COG0769@2|Bacteria,1MU6P@1224|Proteobacteria,42NKY@68525|delta/epsilon subdivisions,2WJJG@28221|Deltaproteobacteria,2MHKD@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008765,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
k59_217439_1	644282.Deba_0881	1.8e-143	421.0	COG4799@1|root,COG4799@2|Bacteria,1MVAX@1224|Proteobacteria,43AEE@68525|delta/epsilon subdivisions,2WIRF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	PFAM carboxyl transferase	pccB	-	2.1.3.1,2.1.3.15,6.4.1.3	ko:K01966,ko:K17489	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	M00373,M00741	R00353,R01859	RC00040,RC00097,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
k59_148781_1	933262.AXAM01000073_gene3359	2.81e-121	354.0	COG0047@1|root,COG0047@2|Bacteria,1MU4Y@1224|Proteobacteria,42MNY@68525|delta/epsilon subdivisions,2WJ6C@28221|Deltaproteobacteria,2MI5J@213118|Desulfobacterales	28221|Deltaproteobacteria	F	CobB/CobQ-like glutamine amidotransferase domain	purQ	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase_5
k59_148781_2	335543.Sfum_0919	1.4e-16	77.0	COG1148@1|root,COG1148@2|Bacteria,1RB0H@1224|Proteobacteria,42QQV@68525|delta/epsilon subdivisions,2WN7E@28221|Deltaproteobacteria,2MRI3@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	4Fe-4S ferredoxin iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4
k59_118571_1	1280001.BAOA01000027_gene4849	5.43e-73	227.0	COG1028@1|root,COG1028@2|Bacteria,1MWB6@1224|Proteobacteria,1RMZB@1236|Gammaproteobacteria,1XSTX@135623|Vibrionales	135623|Vibrionales	IQ	Enoyl-(Acyl carrier protein) reductase	kduD	-	1.1.1.127	ko:K00065	ko00040,map00040	-	R01542	RC00089	ko00000,ko00001,ko01000	-	-	-	adh_short_C2
k59_217443_1	879212.DespoDRAFT_03390	1.58e-155	447.0	COG0581@1|root,COG0581@2|Bacteria,1MUWB@1224|Proteobacteria,42MWK@68525|delta/epsilon subdivisions,2WJKH@28221|Deltaproteobacteria,2MJ8E@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Domain of unknown function (DUF3333)	pstA	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1,DUF3333
k59_233231_2	335543.Sfum_0458	2.39e-106	323.0	COG1884@1|root,COG1884@2|Bacteria,1MUXX@1224|Proteobacteria,42P03@68525|delta/epsilon subdivisions,2WIPY@28221|Deltaproteobacteria,2MR53@213462|Syntrophobacterales	28221|Deltaproteobacteria	I	PFAM Methylmalonyl-CoA mutase	-	-	5.4.99.2	ko:K01848	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
k59_134524_1	1121456.ATVA01000011_gene1345	1.4e-98	309.0	COG2204@1|root,COG4191@1|root,COG2204@2|Bacteria,COG4191@2|Bacteria,1QZPK@1224|Proteobacteria,42NQE@68525|delta/epsilon subdivisions,2WJPH@28221|Deltaproteobacteria,2M8MZ@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,PAS_4,PAS_9,Response_reg
k59_179211_1	1121405.dsmv_0994	1.1e-29	119.0	COG0589@1|root,COG0589@2|Bacteria,1RF1N@1224|Proteobacteria,42S7A@68525|delta/epsilon subdivisions,2WNZK@28221|Deltaproteobacteria,2MKM5@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
k59_104078_1	96561.Dole_0965	1.19e-22	89.0	COG3360@1|root,COG3360@2|Bacteria,1Q2I5@1224|Proteobacteria,42VRR@68525|delta/epsilon subdivisions,2WRD2@28221|Deltaproteobacteria,2MM0N@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Dodecin	-	-	-	ko:K09165	-	-	-	-	ko00000	-	-	-	Dodecin
k59_104078_2	1121861.KB899938_gene4005	4.48e-13	67.4	COG1397@1|root,COG1397@2|Bacteria,1Q397@1224|Proteobacteria,2VA7H@28211|Alphaproteobacteria,2JUZ5@204441|Rhodospirillales	204441|Rhodospirillales	O	ADP-ribosylglycohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	ADP_ribosyl_GH
k59_13325_1	1125863.JAFN01000001_gene224	7.71e-97	302.0	COG0243@1|root,COG0243@2|Bacteria,1NR6J@1224|Proteobacteria,43BMM@68525|delta/epsilon subdivisions,2WJJV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
k59_65576_1	335543.Sfum_4074	2.32e-64	209.0	COG1541@1|root,COG1541@2|Bacteria,1MV1W@1224|Proteobacteria,42MSQ@68525|delta/epsilon subdivisions,2WISJ@28221|Deltaproteobacteria,2MR7M@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)	paaK-1	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C_2
k59_210342_2	439235.Dalk_4194	3.3e-238	665.0	COG3385@1|root,COG3385@2|Bacteria,1R97Q@1224|Proteobacteria,42UH7@68525|delta/epsilon subdivisions,2X6SD@28221|Deltaproteobacteria,2MPID@213118|Desulfobacterales	28221|Deltaproteobacteria	L	PFAM transposase IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_5
k59_27523_1	1499967.BAYZ01000035_gene1060	5.04e-131	391.0	COG1032@1|root,COG1032@2|Bacteria,2NQAV@2323|unclassified Bacteria	2|Bacteria	C	Domain of unknown function (DUF4070)	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,DUF4070,Radical_SAM
k59_62862_2	706587.Desti_3760	9.02e-48	162.0	COG0446@1|root,COG0446@2|Bacteria,1NR3M@1224|Proteobacteria,42RT4@68525|delta/epsilon subdivisions,2WNFI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2
k59_237229_1	330214.NIDE4145	1.36e-74	236.0	COG1004@1|root,COG1004@2|Bacteria,3J0EJ@40117|Nitrospirae	40117|Nitrospirae	C	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	-	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
k59_214350_1	1151117.AJLF01000001_gene756	3.09e-58	196.0	COG0541@1|root,arCOG01228@2157|Archaea,2XTWX@28890|Euryarchaeota,24377@183968|Thermococci	183968|Thermococci	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY	srp54	-	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
k59_108218_1	1382359.JIAL01000001_gene2796	1.35e-08	57.0	COG0332@1|root,COG0332@2|Bacteria,3Y2Z5@57723|Acidobacteria,2JIAW@204432|Acidobacteriia	204432|Acidobacteriia	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
k59_93061_2	551789.ATVJ01000001_gene938	8.94e-18	87.4	COG0602@1|root,COG0602@2|Bacteria,1MUJ2@1224|Proteobacteria,2TU1S@28211|Alphaproteobacteria,43WAY@69657|Hyphomonadaceae	28211|Alphaproteobacteria	H	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds	queE	-	4.3.99.3	ko:K10026	ko00790,ko01100,map00790,map01100	-	R10002	RC02989	ko00000,ko00001,ko01000,ko03016	-	-	-	Fer4_14,Radical_SAM
k59_62872_1	479433.Caci_3657	8.57e-34	133.0	COG0043@1|root,COG0043@2|Bacteria,2GKSI@201174|Actinobacteria	201174|Actinobacteria	H	Belongs to the UbiD family	-	-	4.1.1.98	ko:K03182	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04985,R04986	RC00391	ko00000,ko00001,ko00002,ko01000	-	-	-	UbiD
k59_131622_1	1894.JOER01000001_gene5156	5.18e-33	130.0	COG3845@1|root,COG3845@2|Bacteria,2I2Y2@201174|Actinobacteria	201174|Actinobacteria	P	ABC transporter, ATP-binding protein	-	-	-	ko:K16786,ko:K16787	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ABC_tran
k59_108691_1	1089548.KI783301_gene1263	6.39e-07	56.2	COG0477@1|root,COG2814@2|Bacteria,1VSW8@1239|Firmicutes,4HUQC@91061|Bacilli,3WG73@539002|Bacillales incertae sedis	91061|Bacilli	EGP	Sugar (and other) transporter	bmr3	-	-	-	-	-	-	-	-	-	-	-	MFS_1
k59_101372_1	1121403.AUCV01000005_gene345	6.91e-99	307.0	COG0471@1|root,COG0471@2|Bacteria,1MU0K@1224|Proteobacteria,42MR7@68525|delta/epsilon subdivisions,2WIKA@28221|Deltaproteobacteria,2MIU8@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Citrate transporter	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS,Na_sulph_symp,TrkA_C
k59_17638_1	1121405.dsmv_3058	3.97e-108	318.0	COG0752@1|root,COG0752@2|Bacteria,1MVCJ@1224|Proteobacteria,42MNQ@68525|delta/epsilon subdivisions,2WJJW@28221|Deltaproteobacteria,2MI7B@213118|Desulfobacterales	28221|Deltaproteobacteria	J	PFAM glycyl-tRNA synthetase alpha subunit	glyQ	-	6.1.1.14	ko:K01878	ko00970,map00970	M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iAF987.Gmet_2942	tRNA-synt_2e
k59_2483_1	439235.Dalk_1444	1.88e-16	80.1	COG0845@1|root,COG0845@2|Bacteria,1PEVY@1224|Proteobacteria,42NTH@68525|delta/epsilon subdivisions,2WJ8N@28221|Deltaproteobacteria,2MIMX@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
k59_32915_1	941449.dsx2_0698	3.67e-58	187.0	COG0310@1|root,COG0310@2|Bacteria,1RJRC@1224|Proteobacteria,42QZ5@68525|delta/epsilon subdivisions,2WMQX@28221|Deltaproteobacteria,2MB0Q@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	PFAM cobalamin (vitamin B12) biosynthesis CbiM	cbiM	-	-	ko:K02007	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	CbiM
k59_184818_2	1265505.ATUG01000002_gene1501	4.84e-35	122.0	COG3370@1|root,COG3370@2|Bacteria,1N27G@1224|Proteobacteria,42TID@68525|delta/epsilon subdivisions,2X5QM@28221|Deltaproteobacteria,2MM1R@213118|Desulfobacterales	28221|Deltaproteobacteria	S	DsrE/DsrF-like family	-	-	-	-	-	-	-	-	-	-	-	-	DrsE
k59_154511_1	1312954.KI914854_gene2444	6.09e-34	128.0	2DBV7@1|root,2ZB9P@2|Bacteria,2IGRZ@201174|Actinobacteria	201174|Actinobacteria	S	Domain of unknown function (DUF4386)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4386
k59_230149_1	243231.GSU0212	1.29e-71	223.0	COG1101@1|root,COG1101@2|Bacteria,1MVDM@1224|Proteobacteria,42N3W@68525|delta/epsilon subdivisions,2WJD3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM ABC transporter related	-	-	-	ko:K05833	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_tran
k59_230152_1	768710.DesyoDRAFT_3850	1.07e-56	184.0	COG0410@1|root,COG0410@2|Bacteria,1TPW4@1239|Firmicutes,247PN@186801|Clostridia,260MZ@186807|Peptococcaceae	186801|Clostridia	E	PFAM ABC transporter	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
k59_214819_1	933262.AXAM01000047_gene2347	9.86e-25	98.2	2AHWK@1|root,3189G@2|Bacteria,1NNBX@1224|Proteobacteria,42XJ6@68525|delta/epsilon subdivisions,2WSXC@28221|Deltaproteobacteria,2MM93@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_55910_1	643562.Daes_2906	4.73e-48	175.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MC4@68525|delta/epsilon subdivisions,2WIZU@28221|Deltaproteobacteria,2M97J@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	PFAM ATP-binding region ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_9,Response_reg
k59_17654_1	143224.JQMD01000002_gene2717	0.000811	45.8	COG2182@1|root,COG2182@2|Bacteria,4PKIT@976|Bacteroidetes,1IJAD@117743|Flavobacteriia	976|Bacteroidetes	G	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_214827_1	1121405.dsmv_0998	2.41e-52	172.0	COG1418@1|root,COG1418@2|Bacteria,1RJ5H@1224|Proteobacteria,42SFF@68525|delta/epsilon subdivisions,2WP85@28221|Deltaproteobacteria,2MK90@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	-	-	-	-	-	-	-	-	-	HD
k59_48108_1	439235.Dalk_0002	4.43e-59	198.0	COG0593@1|root,COG0593@2|Bacteria,1MU5H@1224|Proteobacteria,42MA0@68525|delta/epsilon subdivisions,2WJAT@28221|Deltaproteobacteria,2MHNX@213118|Desulfobacterales	28221|Deltaproteobacteria	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	-	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
k59_93603_1	1227352.C173_20691	0.000721	44.3	COG2152@1|root,COG2152@2|Bacteria,1TQE7@1239|Firmicutes,4I6ES@91061|Bacilli,26SI2@186822|Paenibacillaceae	91061|Bacilli	G	glycosidase	-	-	2.4.1.319,2.4.1.320	ko:K18785	-	-	R10811,R10829	RC00049	ko00000,ko01000	-	-	-	Glyco_hydro_130
k59_93603_2	1089553.Tph_c29110	9.99e-32	122.0	COG0438@1|root,COG0662@1|root,COG0438@2|Bacteria,COG0662@2|Bacteria,1TS5D@1239|Firmicutes,24DQ1@186801|Clostridia,42HSC@68295|Thermoanaerobacterales	186801|Clostridia	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1,MannoseP_isomer
k59_17661_1	1540257.JQMW01000009_gene2806	1.95e-07	52.0	COG1136@1|root,COG1136@2|Bacteria,1TQC9@1239|Firmicutes,248Z6@186801|Clostridia,36EK4@31979|Clostridiaceae	186801|Clostridia	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
k59_17661_2	1476973.JMMB01000007_gene2216	1.92e-17	83.2	COG2454@1|root,COG2454@2|Bacteria,1V42I@1239|Firmicutes,24BAF@186801|Clostridia,25T3Z@186804|Peptostreptococcaceae	186801|Clostridia	S	Protein of unknown function (DUF434)	-	-	-	-	-	-	-	-	-	-	-	-	DUF434
k59_32942_1	933262.AXAM01000041_gene1892	4.78e-94	294.0	COG0443@1|root,COG0443@2|Bacteria,1MVEN@1224|Proteobacteria,42M64@68525|delta/epsilon subdivisions,2WIWS@28221|Deltaproteobacteria,2MJ2X@213118|Desulfobacterales	28221|Deltaproteobacteria	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
k59_70798_1	156889.Mmc1_3419	5.66e-51	168.0	COG0756@1|root,COG0756@2|Bacteria,1RA7P@1224|Proteobacteria,2U7B5@28211|Alphaproteobacteria	28211|Alphaproteobacteria	F	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA	dut	GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576	3.6.1.23	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	M00053	R02100,R11896	RC00002	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	dUTPase
k59_108710_1	1041930.Mtc_2078	4.71e-23	104.0	COG3356@1|root,arCOG04351@2157|Archaea,2XVEY@28890|Euryarchaeota,2NAJK@224756|Methanomicrobia	224756|Methanomicrobia	S	Predicted membrane protein (DUF2070)	-	-	-	ko:K08979	-	-	-	-	ko00000	-	-	-	DUF2070
k59_55919_1	292459.STH1268	1.3e-31	127.0	COG1306@1|root,COG1306@2|Bacteria,1TQZV@1239|Firmicutes,24ADG@186801|Clostridia	186801|Clostridia	M	Putative glycosyl hydrolase domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4015
k59_32949_1	1121405.dsmv_2713	3.56e-58	188.0	COG0024@1|root,COG0024@2|Bacteria,1MU99@1224|Proteobacteria,42MM5@68525|delta/epsilon subdivisions,2WJMN@28221|Deltaproteobacteria,2MIBA@213118|Desulfobacterales	28221|Deltaproteobacteria	J	TIGRFAM methionine aminopeptidase, type I	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24,SEC-C
k59_222719_1	933262.AXAM01000008_gene1971	2.28e-103	310.0	COG0172@1|root,COG0172@2|Bacteria,1MUJF@1224|Proteobacteria,42M7H@68525|delta/epsilon subdivisions,2WIT7@28221|Deltaproteobacteria,2MI2A@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iAF987.Gmet_3528	Seryl_tRNA_N,tRNA-synt_2b
k59_63445_5	1096546.WYO_0205	2.78e-34	125.0	COG0647@1|root,COG0647@2|Bacteria	2|Bacteria	G	UMP catabolic process	nagD	-	2.7.1.25,3.1.3.41	ko:K00860,ko:K01101	ko00230,ko00627,ko00920,ko01100,ko01120,map00230,map00627,map00920,map01100,map01120	M00176	R00509,R03024,R04928	RC00002,RC00078,RC00151	ko00000,ko00001,ko00002,ko01000	-	-	-	Hydrolase_6,Hydrolase_like
k59_63445_9	568816.Acin_1991	4.86e-103	323.0	COG0553@1|root,COG0553@2|Bacteria,1TPFZ@1239|Firmicutes,4H2W4@909932|Negativicutes	909932|Negativicutes	L	SNF2 family	-	-	-	-	-	-	-	-	-	-	-	-	SNF2_N
k59_63445_11	1384066.JAGT01000001_gene962	4.04e-61	223.0	COG0749@1|root,COG0749@2|Bacteria,1TPTJ@1239|Firmicutes,2487V@186801|Clostridia,3WHUH@541000|Ruminococcaceae	186801|Clostridia	L	Psort location Cytoplasmic, score	-	-	2.7.7.7	ko:K02334	-	-	-	-	ko00000,ko01000	-	-	-	DNA_pol_A
k59_63445_13	936573.HMPREF1147_1587	9.58e-18	89.0	COG2887@1|root,COG2887@2|Bacteria,1TPIC@1239|Firmicutes,4H2UC@909932|Negativicutes	909932|Negativicutes	L	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	DUF2800
k59_192163_1	439235.Dalk_5206	3.3e-46	166.0	2A7N3@1|root,30WK3@2|Bacteria,1NERD@1224|Proteobacteria,42P7M@68525|delta/epsilon subdivisions,2WJTH@28221|Deltaproteobacteria,2MIHK@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_101439_1	1385935.N836_19385	5.94e-39	137.0	COG1247@1|root,COG1247@2|Bacteria,1G5X1@1117|Cyanobacteria,1HBWI@1150|Oscillatoriales	1117|Cyanobacteria	M	Gcn5-related n-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,FR47
k59_146647_2	335543.Sfum_0813	3.26e-62	205.0	COG0624@1|root,COG0624@2|Bacteria,1MW20@1224|Proteobacteria,42N09@68525|delta/epsilon subdivisions,2WIRX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Peptidase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
k59_25408_1	439235.Dalk_4964	3.57e-87	268.0	COG1035@1|root,COG1146@1|root,COG1035@2|Bacteria,COG1146@2|Bacteria,1MWJC@1224|Proteobacteria,42QB3@68525|delta/epsilon subdivisions,2WM0Q@28221|Deltaproteobacteria,2MIXS@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM Coenzyme F420 hydrogenase dehydrogenase, beta subunit	-	-	1.12.98.1	ko:K00441	ko00680,ko01100,ko01120,map00680,map01100,map01120	-	R03025	RC02628	ko00000,ko00001,ko01000	-	-	-	Fer4,Fer4_10,FrhB_FdhB_C,FrhB_FdhB_N
k59_192165_1	886293.Sinac_7397	7.76e-67	218.0	COG1861@1|root,COG1861@2|Bacteria,2J3F7@203682|Planctomycetes	203682|Planctomycetes	M	PFAM Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_4
k59_32967_1	439235.Dalk_4108	9.19e-29	114.0	COG1215@1|root,COG1215@2|Bacteria,1MWH9@1224|Proteobacteria,42PX0@68525|delta/epsilon subdivisions,2WJUG@28221|Deltaproteobacteria,2MK7E@213118|Desulfobacterales	28221|Deltaproteobacteria	M	COG0463 Glycosyltransferases involved in cell wall biogenesis	-	-	2.4.1.266	ko:K13693	-	-	-	-	ko00000,ko01000,ko01003	-	GT81	-	-
k59_108719_2	96561.Dole_1486	1.07e-108	321.0	COG1235@1|root,COG1235@2|Bacteria,1NW4Z@1224|Proteobacteria,42PTI@68525|delta/epsilon subdivisions,2WIWT@28221|Deltaproteobacteria,2MIKY@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
k59_237819_1	439235.Dalk_5090	4.23e-93	302.0	COG1018@1|root,COG1148@1|root,COG1018@2|Bacteria,COG1148@2|Bacteria,1QUM4@1224|Proteobacteria,42MPP@68525|delta/epsilon subdivisions,2WJ3U@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	4Fe-4S ferredoxin iron-sulfur binding domain protein	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_4,Fer4_7,Pyr_redox_2
k59_17696_1	690850.Desaf_1238	7.4e-50	166.0	COG2165@1|root,COG2165@2|Bacteria,1RDX2@1224|Proteobacteria,42SFB@68525|delta/epsilon subdivisions,2WP3B@28221|Deltaproteobacteria,2MBZA@213115|Desulfovibrionales	28221|Deltaproteobacteria	U	PFAM type II secretion system protein G	gspG	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,T2SSG
k59_139349_1	1125863.JAFN01000001_gene2649	1.99e-50	178.0	COG2414@1|root,COG2414@2|Bacteria,1MWBB@1224|Proteobacteria,42NR7@68525|delta/epsilon subdivisions,2WK49@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM Aldehyde ferredoxin oxidoreductase	-	-	1.2.7.5	ko:K03738	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00309	R08571	RC00242	ko00000,ko00001,ko00002,ko01000	-	-	-	AFOR_C,AFOR_N
k59_32978_1	207559.Dde_2494	2.86e-70	223.0	COG3177@1|root,COG3177@2|Bacteria,1MWAU@1224|Proteobacteria,42P1X@68525|delta/epsilon subdivisions,2WKWC@28221|Deltaproteobacteria,2MAX7@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	filamentation induced by cAMP	-	-	-	-	-	-	-	-	-	-	-	-	Fic,HTH_24
k59_25422_2	1293054.HSACCH_01202	3.58e-48	171.0	COG0168@1|root,COG0168@2|Bacteria,1TPAF@1239|Firmicutes,248K4@186801|Clostridia,3WB17@53433|Halanaerobiales	186801|Clostridia	P	PFAM Cation	trkH	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
k59_48138_2	398767.Glov_0872	3.11e-21	91.3	COG1211@1|root,COG1211@2|Bacteria,1MY3B@1224|Proteobacteria,42RJ4@68525|delta/epsilon subdivisions,2WNQ3@28221|Deltaproteobacteria,43SZQ@69541|Desulfuromonadales	28221|Deltaproteobacteria	I	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)	ispD	GO:0003674,GO:0003824,GO:0016740,GO:0016772,GO:0016779,GO:0050518,GO:0070567	2.7.7.60	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD,adh_short
k59_214855_1	338963.Pcar_1089	1.89e-71	225.0	COG0583@1|root,COG0583@2|Bacteria,1MWVB@1224|Proteobacteria,42U9X@68525|delta/epsilon subdivisions,2WQN5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	Bacterial regulatory helix-turn-helix protein, lysR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
k59_63461_1	1121456.ATVA01000003_gene3021	5.77e-10	61.2	COG0642@1|root,COG5002@1|root,COG0642@2|Bacteria,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,42NK9@68525|delta/epsilon subdivisions,2WMCQ@28221|Deltaproteobacteria,2MH9G@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Response_reg
k59_146665_2	472759.Nhal_3796	1.37e-22	90.9	COG1872@1|root,COG1872@2|Bacteria,1MZ4E@1224|Proteobacteria,1S9AB@1236|Gammaproteobacteria,1WYTV@135613|Chromatiales	135613|Chromatiales	S	Belongs to the UPF0235 family	-	-	-	ko:K09131	-	-	-	-	ko00000	-	-	-	DUF167
k59_70818_1	392499.Swit_5197	4.33e-25	106.0	COG3547@1|root,COG3547@2|Bacteria,1MW0N@1224|Proteobacteria,2TUGE@28211|Alphaproteobacteria,2K3NU@204457|Sphingomonadales	204457|Sphingomonadales	L	Protein involved in DNA binding and transposition, DNA-mediated	-	-	-	ko:K07486	-	-	-	-	ko00000	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_63462_1	933262.AXAM01000038_gene898	1.71e-78	240.0	COG3640@1|root,COG3640@2|Bacteria,1R819@1224|Proteobacteria,42PQR@68525|delta/epsilon subdivisions,2WKE4@28221|Deltaproteobacteria,2MIKC@213118|Desulfobacterales	28221|Deltaproteobacteria	D	PFAM Cobyrinic acid ac-diamide synthase	-	-	-	ko:K07321	-	-	-	-	ko00000	-	-	-	CbiA
k59_232174_1	1121396.KB893100_gene4319	7.68e-110	354.0	COG0493@1|root,COG1148@1|root,COG0493@2|Bacteria,COG1148@2|Bacteria,1QUM4@1224|Proteobacteria,42MPP@68525|delta/epsilon subdivisions,2WJ3U@28221|Deltaproteobacteria,2MIA4@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_20,Fer4_7,Pyr_redox_2
k59_72768_1	1385935.N836_14920	1.64e-11	73.2	COG2267@1|root,COG4188@1|root,COG2267@2|Bacteria,COG4188@2|Bacteria,1G2EN@1117|Cyanobacteria,1H7RF@1150|Oscillatoriales	1117|Cyanobacteria	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4
k59_171260_1	1125863.JAFN01000001_gene2080	4.23e-92	279.0	COG0535@1|root,COG0535@2|Bacteria,1MU07@1224|Proteobacteria,42QKH@68525|delta/epsilon subdivisions,2WMW7@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM Radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF3641,Fer4_12,Radical_SAM
k59_133539_1	335543.Sfum_0184	3.98e-67	216.0	COG0330@1|root,COG0330@2|Bacteria,1MUM2@1224|Proteobacteria,42NUT@68525|delta/epsilon subdivisions,2WKQX@28221|Deltaproteobacteria,2MRX6@213462|Syntrophobacterales	28221|Deltaproteobacteria	O	HflC and HflK could encode or regulate a protease	hflK	-	-	ko:K04088	-	M00742	-	-	ko00000,ko00002,ko01000	-	-	-	Band_7
k59_49686_1	443143.GM18_4037	3.58e-44	164.0	COG1361@1|root,COG4932@1|root,COG1361@2|Bacteria,COG4932@2|Bacteria,1R5G4@1224|Proteobacteria,42T0V@68525|delta/epsilon subdivisions,2WPRT@28221|Deltaproteobacteria,43TPS@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Domain of unknown function DUF11	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,SdrD_B
k59_110666_1	765420.OSCT_0353	1.03e-88	270.0	COG0059@1|root,COG0059@2|Bacteria,2G5NP@200795|Chloroflexi,3758Y@32061|Chloroflexia	32061|Chloroflexia	EH	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate	ilvC	-	1.1.1.86	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R03051,R04439,R04440,R05068,R05069,R05071	RC00726,RC00836,RC00837,RC01726	ko00000,ko00001,ko00002,ko01000	-	-	-	IlvC,IlvN
k59_117664_1	104355.XP_007867967.1	3.34e-69	229.0	COG0442@1|root,KOG4163@2759|Eukaryota,39QW5@33154|Opisthokonta,3NWAQ@4751|Fungi,3UYFP@5204|Basidiomycota,2274R@155619|Agaricomycetes,3H2R7@355688|Agaricomycetes incertae sedis	4751|Fungi	J	prolyl-tRNA synthetase	-	GO:0002161,GO:0002181,GO:0003674,GO:0003824,GO:0004812,GO:0004827,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006433,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0017101,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0043907,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,ProRS-C_1,tRNA-synt_2b,tRNA_edit
k59_163252_1	933262.AXAM01000041_gene1914	1.56e-58	188.0	COG2360@1|root,COG2360@2|Bacteria,1R9W8@1224|Proteobacteria,42QRC@68525|delta/epsilon subdivisions,2WMP7@28221|Deltaproteobacteria,2MHMA@213118|Desulfobacterales	28221|Deltaproteobacteria	O	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine	aat	-	2.3.2.6	ko:K00684	-	-	R03813,R11443,R11444	RC00055,RC00064	ko00000,ko01000	-	-	-	Leu_Phe_trans
k59_72780_1	926549.KI421517_gene2173	1.21e-24	103.0	COG1451@1|root,COG1451@2|Bacteria,4NNY6@976|Bacteroidetes,47QZY@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function DUF45	-	-	-	ko:K07043	-	-	-	-	ko00000	-	-	-	DUF45
k59_72780_2	251221.35212676	2.48e-08	54.7	COG2256@1|root,COG2256@2|Bacteria,1G36R@1117|Cyanobacteria	1117|Cyanobacteria	L	ATPase related to the helicase subunit of the Holliday junction resolvase	mgs1	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA,AAA_assoc_2,MgsA_C,RuvB_N
k59_186782_1	1121438.JNJA01000003_gene2875	5.24e-113	342.0	2AHF9@1|root,317SI@2|Bacteria,1NRCX@1224|Proteobacteria,42YHM@68525|delta/epsilon subdivisions,2WU4T@28221|Deltaproteobacteria,2MANK@213115|Desulfovibrionales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_238994_2	96561.Dole_0299	6.85e-18	82.0	COG1355@1|root,COG1355@2|Bacteria,1MXK5@1224|Proteobacteria,42R55@68525|delta/epsilon subdivisions,2WKKG@28221|Deltaproteobacteria,2MJ1F@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Memo-like protein	-	-	-	ko:K06990	-	-	-	-	ko00000,ko04812	-	-	-	Memo
k59_133545_1	177437.HRM2_26620	4.36e-55	187.0	COG1058@1|root,COG1546@1|root,COG1058@2|Bacteria,COG1546@2|Bacteria,1RH2Y@1224|Proteobacteria,42MQ4@68525|delta/epsilon subdivisions,2WMDT@28221|Deltaproteobacteria,2MHNR@213118|Desulfobacterales	28221|Deltaproteobacteria	S	TIGRFAM competence damage-inducible protein CinA	cinA	GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363	3.5.1.42	ko:K03742,ko:K03743	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA,MoCF_biosynth
k59_80405_1	998088.B565_2356	9.94e-37	142.0	COG1008@1|root,COG1008@2|Bacteria,1MV7V@1224|Proteobacteria,1RNI4@1236|Gammaproteobacteria,1Y5IX@135624|Aeromonadales	135624|Aeromonadales	C	Proton-conducting membrane transporter	-	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
k59_72786_1	1423806.JCM15457_90	1.4e-08	62.0	COG0500@1|root,COG2226@2|Bacteria,1TQUF@1239|Firmicutes,4HD2W@91061|Bacilli,3F4KM@33958|Lactobacillaceae	91061|Bacilli	Q	Methyltransferase	yqeM	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
k59_87619_1	933262.AXAM01000001_gene330	9.32e-21	98.6	COG1466@1|root,COG1466@2|Bacteria,1RAEB@1224|Proteobacteria,42R0X@68525|delta/epsilon subdivisions,2WMQJ@28221|Deltaproteobacteria,2MJNX@213118|Desulfobacterales	28221|Deltaproteobacteria	L	DNA polymerase III, delta'	holA	-	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta
k59_87619_2	620914.JH621254_gene498	0.000749	49.7	COG4948@1|root,COG4948@2|Bacteria,4NEBX@976|Bacteroidetes,1HY3V@117743|Flavobacteriia,2YIFP@290174|Aquimarina	976|Bacteroidetes	M	Mandelate racemase / muconate lactonizing enzyme, C-terminal domain	menC	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C
k59_103087_1	290397.Adeh_0695	1e-35	140.0	COG1032@1|root,COG5011@1|root,COG1032@2|Bacteria,COG5011@2|Bacteria,1MV5G@1224|Proteobacteria,42MPT@68525|delta/epsilon subdivisions,2WJG9@28221|Deltaproteobacteria,2YUJ4@29|Myxococcales	28221|Deltaproteobacteria	C	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	DUF2344,Radical_SAM
k59_41863_1	1121405.dsmv_3106	2.61e-128	375.0	COG1219@1|root,COG1219@2|Bacteria,1MVQK@1224|Proteobacteria,42MWJ@68525|delta/epsilon subdivisions,2WJ8Q@28221|Deltaproteobacteria,2MHKY@213118|Desulfobacterales	28221|Deltaproteobacteria	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
k59_156260_1	1121405.dsmv_2161	1.28e-61	205.0	COG0459@1|root,COG0459@2|Bacteria,1MURR@1224|Proteobacteria,42M52@68525|delta/epsilon subdivisions,2WIRK@28221|Deltaproteobacteria,2MHPV@213118|Desulfobacterales	28221|Deltaproteobacteria	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	-	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
k59_209390_2	765420.OSCT_2349	5.1e-09	57.8	COG0642@1|root,COG2199@1|root,COG0642@2|Bacteria,COG3706@2|Bacteria	2|Bacteria	T	GGDEF domain	-	-	4.6.1.1	ko:K01768,ko:K20977	ko00230,ko02020,ko02025,ko04113,ko04213,map00230,map02020,map02025,map04113,map04213	M00695,M00820	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000,ko02022	-	-	-	DUF3404,GAF,HATPase_c,HATPase_c_2,HisKA,Response_reg,SpoIIE
k59_118262_1	1078020.KEK_21425	1.97e-05	46.2	COG0440@1|root,COG0440@2|Bacteria,2GJCH@201174|Actinobacteria,235KD@1762|Mycobacteriaceae	201174|Actinobacteria	E	acetolactate synthase, small	ilvN	GO:0003674,GO:0003824,GO:0003984,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005948,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0030312,GO:0032991,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234	2.2.1.6	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,ACT_5,ALS_ss_C
k59_118262_2	177439.DP0453	7.41e-44	153.0	COG0429@1|root,COG0429@2|Bacteria,1MWV1@1224|Proteobacteria,42N26@68525|delta/epsilon subdivisions,2WK9Q@28221|Deltaproteobacteria,2MQ1U@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Serine aminopeptidase, S33	-	-	-	ko:K07019	-	-	-	-	ko00000	-	-	-	Abhydrolase_1,Hydrolase_4
k59_4211_1	1281779.H009_24971	5.04e-14	73.6	COG3278@1|root,COG3278@2|Bacteria,1MU18@1224|Proteobacteria,2TR2C@28211|Alphaproteobacteria,4B9Q6@82115|Rhizobiaceae	28211|Alphaproteobacteria	C	Belongs to the heme-copper respiratory oxidase family	ccoN	GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015672,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0022900,GO:0022904,GO:0034220,GO:0044237,GO:0044464,GO:0045333,GO:0051179,GO:0051234,GO:0055085,GO:0055114,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:1902600	1.9.3.1	ko:K00404	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	COX1
k59_4211_2	998674.ATTE01000001_gene1726	4.14e-09	59.3	COG1959@1|root,COG1959@2|Bacteria,1RDA4@1224|Proteobacteria,1S3RW@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins	iscR	-	-	ko:K13643	-	-	-	-	ko00000,ko03000	-	-	-	Rrf2
k59_126704_2	526222.Desal_0677	7.75e-16	82.4	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,2M7UM@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	Two component, sigma54 specific, transcriptional regulator, Fis family	-	-	-	ko:K02481,ko:K07713	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
k59_156875_1	1048834.TC41_0990	2.77e-81	248.0	COG0605@1|root,COG0605@2|Bacteria,1TPXT@1239|Firmicutes,4HA6U@91061|Bacilli,2781X@186823|Alicyclobacillaceae	91061|Bacilli	P	Destroys radicals which are normally produced within the cells and which are toxic to biological systems	sodA	-	1.15.1.1	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Fe_C,Sod_Fe_N
k59_81074_1	1122947.FR7_3923	1.33e-72	231.0	COG2896@1|root,COG2896@2|Bacteria,1TP89@1239|Firmicutes,4H3QS@909932|Negativicutes	909932|Negativicutes	H	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate	moaA	-	4.1.99.22	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394	RC03420	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Mob_synth_C,Radical_SAM
k59_171890_1	338966.Ppro_0422	1.35e-52	180.0	COG1066@1|root,COG1066@2|Bacteria,1MUJQ@1224|Proteobacteria,42MG8@68525|delta/epsilon subdivisions,2WJWP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function	radA	-	-	ko:K04485	-	-	-	-	ko00000,ko03400	-	-	-	AAA_25,ATPase,ChlI,Lon_C
k59_178994_1	1453501.JELR01000002_gene1332	2.02e-19	91.3	COG1477@1|root,COG1477@2|Bacteria,1MW6K@1224|Proteobacteria,1RNMZ@1236|Gammaproteobacteria,4658H@72275|Alteromonadaceae	1236|Gammaproteobacteria	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	-	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
k59_156881_1	68194.JNXR01000003_gene3028	6.49e-12	66.6	COG1618@1|root,COG1618@2|Bacteria,2IJWQ@201174|Actinobacteria	201174|Actinobacteria	F	NTPase	-	-	3.6.1.15	ko:K06928	ko00230,ko00730,ko01100,map00230,map00730,map01100	-	R00086,R00615	RC00002	ko00000,ko00001,ko01000	-	-	-	NTPase_1
k59_210020_1	713586.KB900536_gene630	1.36e-35	133.0	COG2801@1|root,COG2801@2|Bacteria,1MZ45@1224|Proteobacteria,1RSNX@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	COG2801 Transposase and inactivated derivatives	ylbG	-	-	-	-	-	-	-	-	-	-	-	HTH_29,rve,rve_2,rve_3
k59_42504_1	292459.STH2369	7.26e-33	128.0	COG0500@1|root,COG2226@2|Bacteria,1U5XV@1239|Firmicutes,24A44@186801|Clostridia	186801|Clostridia	Q	Methyltransferase	arsM	-	2.1.1.137	ko:K07755	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_31
k59_50185_1	1121405.dsmv_2128	4.77e-36	123.0	COG1837@1|root,COG1837@2|Bacteria,1N7IX@1224|Proteobacteria,42TXI@68525|delta/epsilon subdivisions,2WQBS@28221|Deltaproteobacteria,2MKI6@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Belongs to the UPF0109 family	-	-	-	ko:K06960	-	-	-	-	ko00000	-	-	-	KH_4
k59_50185_2	1121015.N789_05280	8.84e-20	88.6	COG0806@1|root,COG0806@2|Bacteria,1MWQR@1224|Proteobacteria,1RNJ2@1236|Gammaproteobacteria,1X63G@135614|Xanthomonadales	135614|Xanthomonadales	J	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes	rimM	-	-	ko:K02860	-	-	-	-	ko00000,ko03009	-	-	-	PRC,RimM
k59_194097_1	471852.Tcur_3655	3.88e-09	62.8	COG0491@1|root,COG0491@2|Bacteria,2GMDD@201174|Actinobacteria,4EI96@85012|Streptosporangiales	201174|Actinobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
k59_50189_1	1122971.BAME01000163_gene6625	9.64e-19	95.5	COG1783@1|root,COG1783@2|Bacteria,4NSQV@976|Bacteroidetes	976|Bacteroidetes	S	Phage terminase large subunit	-	-	-	ko:K06909	-	-	-	-	ko00000	-	-	-	Terminase_3
k59_42516_1	768671.ThimaDRAFT_1470	1.67e-58	192.0	COG0463@1|root,COG0463@2|Bacteria,1RAIY@1224|Proteobacteria	1224|Proteobacteria	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_4
k59_88351_1	335543.Sfum_2956	3.97e-130	389.0	COG1523@1|root,COG1523@2|Bacteria,1MU19@1224|Proteobacteria,42P3J@68525|delta/epsilon subdivisions,2WKFS@28221|Deltaproteobacteria,2MQ9F@213462|Syntrophobacterales	28221|Deltaproteobacteria	G	Belongs to the glycosyl hydrolase 13 family	-	-	3.2.1.68	ko:K01214	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R09995,R11261	-	ko00000,ko00001,ko00002,ko01000	-	CBM48,GH13	-	Alpha-amylase,CBM_48
k59_65376_1	1040987.AZUY01000001_gene2682	4.75e-35	138.0	COG0210@1|root,COG0210@2|Bacteria,1MU0G@1224|Proteobacteria,2TS2B@28211|Alphaproteobacteria,43HBY@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	L	Helicase	uvrD	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
k59_111332_1	706587.Desti_4373	1.5e-48	169.0	COG1030@1|root,COG1030@2|Bacteria,1MUJN@1224|Proteobacteria,42MWM@68525|delta/epsilon subdivisions,2WK3H@28221|Deltaproteobacteria,2MQRK@213462|Syntrophobacterales	28221|Deltaproteobacteria	O	NfeD-like C-terminal, partner-binding	nfeD	-	-	ko:K07403	-	-	-	-	ko00000	-	-	-	CLP_protease,NfeD,SDH_sah
k59_88355_1	1121405.dsmv_2612	1.6e-64	209.0	COG4948@1|root,COG4948@2|Bacteria,1MW76@1224|Proteobacteria,42Q93@68525|delta/epsilon subdivisions,2WKAA@28221|Deltaproteobacteria,2MJ2T@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Mandelate racemase / muconate lactonizing enzyme, C-terminal domain	-	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016854,GO:0034641,GO:0043167,GO:0043169,GO:0043603,GO:0044237,GO:0046872,GO:0071704,GO:1901564	5.1.1.20	ko:K19802	-	-	R10938	RC03309	ko00000,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
k59_224643_1	933262.AXAM01000022_gene3241	1.2e-55	198.0	COG1028@1|root,COG3321@1|root,COG1028@2|Bacteria,COG3321@2|Bacteria,1R89Z@1224|Proteobacteria,42NGA@68525|delta/epsilon subdivisions,2WJK3@28221|Deltaproteobacteria,2MJ23@213118|Desulfobacterales	28221|Deltaproteobacteria	IQ	TIGRFAM Polyketide-type polyunsaturated fatty acid synthase, PfaA	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_1,FabA,KAsynt_C_assoc,KR,Ketoacyl-synt_C,PP-binding,PS-DH,ketoacyl-synt
k59_187518_1	1121405.dsmv_0187	1.27e-92	288.0	COG0465@1|root,COG0465@2|Bacteria,1MU6J@1224|Proteobacteria,42M4Z@68525|delta/epsilon subdivisions,2WJZ3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	-	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
k59_73464_1	105559.Nwat_1372	5.69e-69	219.0	COG0761@1|root,COG0761@2|Bacteria,1MU7G@1224|Proteobacteria,1RMN8@1236|Gammaproteobacteria,1WXJX@135613|Chromatiales	135613|Chromatiales	IM	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis	ispH	-	1.17.7.4	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05884,R08210	RC01137,RC01487	ko00000,ko00001,ko00002,ko01000	-	-	-	LYTB
k59_42530_1	269797.Mbar_A0765	2.72e-85	260.0	COG4925@1|root,arCOG06704@2157|Archaea,2XY6I@28890|Euryarchaeota,2NB4J@224756|Methanomicrobia	224756|Methanomicrobia	I	sulfurtransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_126713_1	96561.Dole_0566	3.07e-47	164.0	COG0004@1|root,COG0004@2|Bacteria,1R50W@1224|Proteobacteria,42PKR@68525|delta/epsilon subdivisions,2WM8P@28221|Deltaproteobacteria,2MII5@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Ammonium Transporter Family	-	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
k59_96087_1	1121405.dsmv_1576	2.03e-58	192.0	COG4123@1|root,COG4123@2|Bacteria,1MXEQ@1224|Proteobacteria,42SAA@68525|delta/epsilon subdivisions,2WPCM@28221|Deltaproteobacteria,2MJTD@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Methyltransferase small domain	-	-	2.1.1.223	ko:K15460	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	MTS,Methyltransf_31
k59_141788_1	335543.Sfum_0851	2.17e-111	332.0	COG0618@1|root,COG0618@2|Bacteria,1N0JS@1224|Proteobacteria,42P1S@68525|delta/epsilon subdivisions,2WJV0@28221|Deltaproteobacteria,2MQTH@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Phosphoesterase RecJ domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DHH,DHHA1
k59_50208_1	1182553.XP_007741078.1	2e-34	121.0	COG1839@1|root,2S1CB@2759|Eukaryota	2759|Eukaryota	S	Adenosine specific kinase	-	-	-	ko:K09129	-	-	-	-	ko00000	-	-	-	Adenosine_kin
k59_50208_2	330214.NIDE0585	2.03e-19	87.8	COG0784@1|root,COG2202@1|root,COG3829@1|root,COG5002@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG3829@2|Bacteria,COG5002@2|Bacteria,3J0ZF@40117|Nitrospirae	2|Bacteria	T	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_9,Response_reg,SBP_bac_3
k59_179014_1	335543.Sfum_2756	1.55e-63	215.0	COG0707@1|root,COG1413@1|root,COG0707@2|Bacteria,COG1413@2|Bacteria,1MVIB@1224|Proteobacteria,42ME1@68525|delta/epsilon subdivisions,2WJNY@28221|Deltaproteobacteria,2MRPC@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
k59_156913_1	1121405.dsmv_1666	1.66e-90	297.0	COG0243@1|root,COG0437@1|root,COG0243@2|Bacteria,COG0437@2|Bacteria,1MU1B@1224|Proteobacteria,42NEG@68525|delta/epsilon subdivisions,2WKHA@28221|Deltaproteobacteria,2MMPS@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	actB	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_7,Molybdop_Fe4S4,Molybdopterin,Molydop_binding
k59_20002_1	335543.Sfum_2075	1.08e-259	724.0	COG0504@1|root,COG0504@2|Bacteria,1MUIT@1224|Proteobacteria,42MEU@68525|delta/epsilon subdivisions,2WJ0F@28221|Deltaproteobacteria,2MQ5R@213462|Syntrophobacterales	28221|Deltaproteobacteria	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1276	CTP_synth_N,GATase
k59_111360_2	365528.KB891230_gene2034	3.27e-08	60.1	COG0860@1|root,COG3409@1|root,COG0860@2|Bacteria,COG3409@2|Bacteria,2GPA9@201174|Actinobacteria,4ERBQ@85013|Frankiales	201174|Actinobacteria	M	Cell wall hydrolase autolysin	cwlM	GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3,PG_binding_1
k59_111361_1	1244869.H261_05249	1.99e-39	145.0	COG2807@1|root,COG2807@2|Bacteria,1QU85@1224|Proteobacteria,2TXRC@28211|Alphaproteobacteria,2JZ2E@204441|Rhodospirillales	204441|Rhodospirillales	P	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
k59_134260_1	273068.TTE1471	0.000187	42.0	COG0236@1|root,COG0236@2|Bacteria,1VEE3@1239|Firmicutes,24QME@186801|Clostridia,42H5S@68295|Thermoanaerobacterales	186801|Clostridia	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
k59_156924_1	136273.GY22_04930	1.96e-12	73.2	COG0305@1|root,COG1372@1|root,COG0305@2|Bacteria,COG1372@2|Bacteria,2GKXQ@201174|Actinobacteria,1W8BX@1268|Micrococcaceae	201174|Actinobacteria	L	Participates in initiation and elongation during chromosome replication	dnaB	GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0030312,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140097,GO:1901360,GO:1901576	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C,Intein_splicing,LAGLIDADG_3
k59_27262_1	1121405.dsmv_1703	3.19e-43	160.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,42NAV@68525|delta/epsilon subdivisions,2WJ3W@28221|Deltaproteobacteria,2MIIB@213118|Desulfobacterales	28221|Deltaproteobacteria	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
k59_65398_1	1121405.dsmv_3800	3.48e-94	292.0	COG0517@1|root,COG0517@2|Bacteria,1MXI6@1224|Proteobacteria,42SSD@68525|delta/epsilon subdivisions,2WPWR@28221|Deltaproteobacteria,2MK6M@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Putative transposase	-	-	-	-	-	-	-	-	-	-	-	-	Y2_Tnp,Zn_Tnp_IS91
k59_233001_1	177437.HRM2_09710	1.05e-71	230.0	COG2710@1|root,COG2710@2|Bacteria,1MWQ4@1224|Proteobacteria,42MNG@68525|delta/epsilon subdivisions,2WIWX@28221|Deltaproteobacteria,2MII6@213118|Desulfobacterales	28221|Deltaproteobacteria	C	This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation	nifK	-	1.18.6.1	ko:K02591	ko00625,ko00910,ko01100,ko01120,map00625,map00910,map01100,map01120	M00175	R05185,R05496	RC00002,RC01395,RC02891	ko00000,ko00001,ko00002,ko01000	-	-	-	Oxidored_nitro
k59_205552_1	334390.LAF_0422	2.36e-06	54.3	COG1502@1|root,COG1502@2|Bacteria,1TPKY@1239|Firmicutes,4H9TI@91061|Bacilli,3F3SF@33958|Lactobacillaceae	91061|Bacilli	I	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol	cls	GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008808,GO:0009058,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0019637,GO:0030572,GO:0032048,GO:0032049,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046471,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:1901576	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2,PLDc_N
k59_106932_2	1322246.BN4_20068	2.24e-43	148.0	COG1348@1|root,COG1348@2|Bacteria,1MVTE@1224|Proteobacteria,42NE5@68525|delta/epsilon subdivisions,2WJ14@28221|Deltaproteobacteria,2M97I@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components the iron protein and the molybdenum-iron protein	nifH	-	1.18.6.1	ko:K02588	ko00625,ko00910,ko01100,ko01120,map00625,map00910,map01100,map01120	M00175	R05185,R05496	RC00002,RC01395,RC02891	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4_NifH
k59_175186_1	439235.Dalk_4801	5.75e-71	226.0	COG3385@1|root,COG3385@2|Bacteria,1PMXF@1224|Proteobacteria,43B8Z@68525|delta/epsilon subdivisions,2X6NB@28221|Deltaproteobacteria,2MPI8@213118|Desulfobacterales	1224|Proteobacteria	L	PFAM transposase IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DUF4372
k59_61581_1	1122149.BACN01000063_gene1917	1.54e-17	81.3	COG2365@1|root,COG2365@2|Bacteria,1V851@1239|Firmicutes,4HJB2@91061|Bacilli,3F55V@33958|Lactobacillaceae	91061|Bacilli	T	Tyrosine phosphatase family	-	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	Y_phosphatase3
k59_15900_1	1121405.dsmv_1743	4.02e-114	338.0	COG3825@1|root,COG3825@2|Bacteria,1MUAJ@1224|Proteobacteria,42N7R@68525|delta/epsilon subdivisions,2WJBI@28221|Deltaproteobacteria,2MIB1@213118|Desulfobacterales	28221|Deltaproteobacteria	S	VWA containing CoxE family protein	-	-	-	ko:K09989	-	-	-	-	ko00000	-	-	-	VWA_CoxE
k59_175189_1	349741.Amuc_1312	6.15e-22	100.0	COG0612@1|root,COG0612@2|Bacteria,46S9I@74201|Verrucomicrobia,2ITJG@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Insulinase (Peptidase family M16)	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
k59_53831_1	1265505.ATUG01000002_gene1272	6.57e-52	172.0	COG1600@1|root,COG1600@2|Bacteria,1RAYI@1224|Proteobacteria,42R4W@68525|delta/epsilon subdivisions,2WK0B@28221|Deltaproteobacteria,2MJVT@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_76658_1	1121438.JNJA01000001_gene2600	6.94e-60	201.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MR8@68525|delta/epsilon subdivisions,2WIUA@28221|Deltaproteobacteria,2MA08@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	histidine kinase HAMP region domain protein	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
k59_84126_1	1265505.ATUG01000002_gene2261	1.2e-58	204.0	COG4191@1|root,COG4191@2|Bacteria,1NSFQ@1224|Proteobacteria,42YV0@68525|delta/epsilon subdivisions,2WUF9@28221|Deltaproteobacteria,2MN2U@213118|Desulfobacterales	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
k59_190251_1	1121396.KB893001_gene3984	8.68e-43	144.0	COG1051@1|root,COG1051@2|Bacteria,1MWNH@1224|Proteobacteria,42T59@68525|delta/epsilon subdivisions,2WPMV@28221|Deltaproteobacteria,2MKE0@213118|Desulfobacterales	28221|Deltaproteobacteria	F	NUDIX domain	-	-	3.6.1.13,3.6.1.55	ko:K01515,ko:K03574	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000,ko03400	-	-	-	NUDIX
k59_46240_1	522772.Dacet_0859	8.88e-27	105.0	COG1406@1|root,COG1406@2|Bacteria,2GFNF@200930|Deferribacteres	200930|Deferribacteres	N	Chemotaxis phosphatase CheX	-	-	-	ko:K03409	ko02030,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheX
k59_46240_2	65393.PCC7424_2263	1.23e-05	53.9	COG2199@1|root,COG3706@2|Bacteria,1G35Y@1117|Cyanobacteria,3KJPD@43988|Cyanothece	1117|Cyanobacteria	T	PFAM GGDEF domain containing protein	-	-	2.7.7.65	ko:K21020	ko02025,map02025	-	-	-	ko00000,ko00001,ko01000	-	-	-	GGDEF,Response_reg
k59_175203_1	1562701.BBOF01000014_gene549	1.13e-13	77.8	COG3344@1|root,COG3344@2|Bacteria,1MVI1@1224|Proteobacteria,2VMDU@28216|Betaproteobacteria,1KH1R@119060|Burkholderiaceae	28216|Betaproteobacteria	L	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	2.7.7.49	ko:K00986	-	-	-	-	ko00000,ko01000	-	-	-	GIIM,RVT_1
k59_61590_1	411476.BACOVA_02757	4.74e-14	76.3	COG0745@1|root,COG3292@1|root,COG5002@1|root,COG0745@2|Bacteria,COG3292@2|Bacteria,COG5002@2|Bacteria,4P0IA@976|Bacteroidetes,2FRPM@200643|Bacteroidia,4AQCE@815|Bacteroidaceae	976|Bacteroidetes	T	Y_Y_Y domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HTH_18,HisKA,Reg_prop,Response_reg,Y_Y_Y
k59_61590_2	96561.Dole_1615	9.92e-17	81.6	COG0745@1|root,COG4191@1|root,COG0745@2|Bacteria,COG4191@2|Bacteria,1NSIT@1224|Proteobacteria,42USH@68525|delta/epsilon subdivisions,2WQNN@28221|Deltaproteobacteria,2MKSH@213118|Desulfobacterales	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HisKA,Response_reg
k59_144808_1	1232437.KL661953_gene2321	3.87e-13	72.0	COG5002@1|root,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	-	-	2.7.13.3,4.6.1.1	ko:K01768,ko:K03406,ko:K18345	ko00230,ko01502,ko02020,ko02025,ko02030,ko04113,ko04213,map00230,map01502,map02020,map02025,map02030,map04113,map04213	M00651,M00656,M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022,ko02035	-	-	-	EAL,GGDEF,GerE,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg,STAS,dCache_1
k59_129646_1	933262.AXAM01000021_gene448	4.6e-89	295.0	COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,42NYP@68525|delta/epsilon subdivisions,2WIPJ@28221|Deltaproteobacteria,2MIG6@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Belongs to the peptidase M16 family	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
k59_220792_1	439235.Dalk_4432	4.14e-89	273.0	COG1127@1|root,COG2199@1|root,COG1127@2|Bacteria,COG2199@2|Bacteria,1MUSD@1224|Proteobacteria,42NI4@68525|delta/epsilon subdivisions,2WKRT@28221|Deltaproteobacteria,2MIVB@213118|Desulfobacterales	28221|Deltaproteobacteria	Q	PFAM ABC transporter	-	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran,GGDEF
k59_137298_1	1026882.MAMP_00498	1.39e-11	59.7	COG5450@1|root,COG5450@2|Bacteria	2|Bacteria	K	positive regulation of growth	-	-	-	-	-	-	-	-	-	-	-	-	VapB_antitoxin
k59_137298_2	1027273.GZ77_21195	1.76e-45	151.0	COG1487@1|root,COG1487@2|Bacteria,1RHIX@1224|Proteobacteria,1S6AM@1236|Gammaproteobacteria,1XPSI@135619|Oceanospirillales	135619|Oceanospirillales	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	-	-	-	-	-	-	-	-	-	PIN
k59_106939_1	261292.Nit79A3_1578	1.24e-56	199.0	COG1262@1|root,COG1262@2|Bacteria,1PWQN@1224|Proteobacteria,2W0G0@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
k59_31098_1	439235.Dalk_0260	6.73e-52	174.0	COG0789@1|root,COG0789@2|Bacteria,1N7M7@1224|Proteobacteria,42WAT@68525|delta/epsilon subdivisions,2WRPH@28221|Deltaproteobacteria,2MMFX@213118|Desulfobacterales	28221|Deltaproteobacteria	K	PFAM regulatory protein MerR	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
k59_137302_1	351348.Maqu_2074	1.09e-42	156.0	COG0446@1|root,COG1902@1|root,COG0446@2|Bacteria,COG1902@2|Bacteria,1MVE0@1224|Proteobacteria,1RNM8@1236|Gammaproteobacteria,4656A@72275|Alteromonadaceae	1236|Gammaproteobacteria	C	COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family	fadH	-	1.3.1.34	ko:K00219	-	-	-	-	ko00000,ko01000	-	-	-	Oxidored_FMN,Pyr_redox_2
k59_137302_2	1408473.JHXO01000005_gene1481	2.2e-42	145.0	COG0778@1|root,COG0778@2|Bacteria,4NPZV@976|Bacteroidetes,2FNIP@200643|Bacteroidia	976|Bacteroidetes	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
k59_129657_1	1459636.NTE_00007	1.23e-46	169.0	COG0417@1|root,arCOG00329@2157|Archaea	2157|Archaea	L	DNA polymerase elongation subunit (Family B)	polB2	-	2.7.7.7	ko:K02319	ko00230,ko00240,ko01100,ko03030,map00230,map00240,map01100,map03030	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032	-	-	-	DNA_pol_B
k59_46254_1	240016.ABIZ01000001_gene2819	3.07e-45	167.0	COG5421@1|root,COG5421@2|Bacteria,46U8B@74201|Verrucomicrobia	74201|Verrucomicrobia	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
k59_99261_1	1286631.X805_07030	6.32e-07	56.2	COG3419@1|root,COG3419@2|Bacteria,1NUAV@1224|Proteobacteria,2VHY8@28216|Betaproteobacteria	28216|Betaproteobacteria	NU	pilus assembly protein tip-associated adhesin	-	-	-	ko:K02674	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	Neisseria_PilC,VWA_2
k59_212991_1	316067.Geob_2939	3.62e-80	251.0	COG0527@1|root,COG0527@2|Bacteria,1MW3H@1224|Proteobacteria,42NDT@68525|delta/epsilon subdivisions,2WIWZ@28221|Deltaproteobacteria,43U9Z@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	PFAM aspartate glutamate uridylate kinase	lysC	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT,ACT_7
k59_38748_1	620914.JH621248_gene3074	6.54e-45	167.0	COG0270@1|root,COG0338@1|root,COG0270@2|Bacteria,COG0338@2|Bacteria,4PIHV@976|Bacteroidetes,1IEAM@117743|Flavobacteriia,2YKYA@290174|Aquimarina	976|Bacteroidetes	L	C-5 cytosine-specific DNA methylase	-	-	-	-	-	-	-	-	-	-	-	-	DNA_methylase
k59_53851_1	717605.Theco_1758	2.35e-51	176.0	COG0324@1|root,COG0324@2|Bacteria,1TPSC@1239|Firmicutes,4HAVW@91061|Bacilli,26RAP@186822|Paenibacillaceae	91061|Bacilli	J	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
k59_152423_1	1232410.KI421424_gene1646	5.95e-17	80.9	COG0583@1|root,COG0583@2|Bacteria,1MWVU@1224|Proteobacteria,42PMQ@68525|delta/epsilon subdivisions,2WKB8@28221|Deltaproteobacteria,43UU2@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
k59_69015_1	396588.Tgr7_1060	4.39e-09	60.5	COG0700@1|root,COG2715@1|root,COG0700@2|Bacteria,COG2715@2|Bacteria,1MVZ0@1224|Proteobacteria,1RRBY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	membrane protein required for spore maturation in B.subtilis	spmB	-	-	ko:K06374	-	-	-	-	ko00000	-	-	-	Gate
k59_15943_1	765914.ThisiDRAFT_0627	2.88e-20	94.7	COG1256@1|root,COG1256@2|Bacteria,1MV2M@1224|Proteobacteria,1RMEA@1236|Gammaproteobacteria,1WW11@135613|Chromatiales	135613|Chromatiales	N	TIGRFAM Flagellar hook-associated protein, FlgK	flgK	-	-	ko:K02396	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod,Flg_bbr_C
k59_122118_1	335543.Sfum_3216	1.8e-52	174.0	COG1413@1|root,COG1413@2|Bacteria,1R6G4@1224|Proteobacteria,42T2X@68525|delta/epsilon subdivisions,2WPNC@28221|Deltaproteobacteria,2MRRI@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,HEAT_EZ
k59_167539_1	335543.Sfum_2756	1.37e-43	169.0	COG0707@1|root,COG1413@1|root,COG0707@2|Bacteria,COG1413@2|Bacteria,1MVIB@1224|Proteobacteria,42ME1@68525|delta/epsilon subdivisions,2WJNY@28221|Deltaproteobacteria,2MRPC@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
k59_235880_1	1123517.JOMR01000001_gene699	1.14e-43	161.0	COG1033@1|root,COG1033@2|Bacteria,1MUE1@1224|Proteobacteria,1RPIP@1236|Gammaproteobacteria,46225@72273|Thiotrichales	72273|Thiotrichales	S	MMPL family	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
k59_167542_1	293826.Amet_3159	5.14e-06	48.5	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247Q0@186801|Clostridia,36DEY@31979|Clostridiaceae	186801|Clostridia	V	ABC transporter transmembrane region	-	-	-	ko:K18889	ko02010,map02010	M00707	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.106.13,3.A.1.106.5	-	-	ABC_membrane,ABC_tran
k59_220822_3	1121024.AUCD01000023_gene726	3.33e-54	184.0	COG2189@1|root,COG2189@2|Bacteria,1UHUQ@1239|Firmicutes,4HCEV@91061|Bacilli	91061|Bacilli	L	Belongs to the N(4) N(6)-methyltransferase family	-	-	2.1.1.72	ko:K00571	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	N6_N4_Mtase
k59_182718_1	1121448.DGI_2232	7.72e-07	52.4	COG0438@1|root,COG0438@2|Bacteria,1MVKK@1224|Proteobacteria,42M7Q@68525|delta/epsilon subdivisions,2WJ9Z@28221|Deltaproteobacteria,2M96J@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
k59_182718_2	690850.Desaf_3054	3.56e-40	144.0	COG0438@1|root,COG0438@2|Bacteria,1R4Q9@1224|Proteobacteria,42M0N@68525|delta/epsilon subdivisions,2WMAJ@28221|Deltaproteobacteria,2M944@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
k59_190286_1	1123371.ATXH01000009_gene1092	8.51e-46	166.0	COG0457@1|root,COG1032@1|root,COG0457@2|Bacteria,COG1032@2|Bacteria,2GI0E@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	C	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
k59_235885_1	1125863.JAFN01000001_gene214	5.49e-55	184.0	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,42PRI@68525|delta/epsilon subdivisions,2X5GA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
k59_129683_1	887898.HMPREF0551_1364	1.33e-41	155.0	COG0178@1|root,COG0178@2|Bacteria,1MW0W@1224|Proteobacteria,2VI87@28216|Betaproteobacteria,1K1YU@119060|Burkholderiaceae	28216|Betaproteobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA2	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
k59_167551_1	1265310.CCBD010000007_gene3077	0.000661	45.8	COG0586@1|root,COG0586@2|Bacteria,2GKKC@201174|Actinobacteria,23EXR@1762|Mycobacteriaceae	201174|Actinobacteria	S	SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
k59_160105_1	983545.Glaag_3267	3.23e-82	253.0	COG0463@1|root,COG0463@2|Bacteria,1MWE5@1224|Proteobacteria,1RPCE@1236|Gammaproteobacteria,464H5@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	COG0463 Glycosyltransferases involved in cell wall biogenesis	-	-	-	ko:K20534	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.2.1.9	GT2	-	Glycos_transf_2
k59_160105_2	903818.KI912268_gene1623	9.31e-10	57.4	COG3952@1|root,COG3952@2|Bacteria	2|Bacteria	S	lipid-A-disaccharide synthase activity	-	-	-	-	-	-	-	-	-	-	-	-	LAB_N
k59_144846_1	457398.HMPREF0326_02460	5.64e-25	100.0	COG0599@1|root,COG0599@2|Bacteria,1QTZH@1224|Proteobacteria,42TJW@68525|delta/epsilon subdivisions,2X9XM@28221|Deltaproteobacteria,2M9YY@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	PFAM Carboxymuconolactone decarboxylase	-	-	-	-	-	-	-	-	-	-	-	-	CMD
k59_144846_2	398767.Glov_1440	5.42e-51	169.0	COG0656@1|root,COG0656@2|Bacteria,1MWFS@1224|Proteobacteria,42PWU@68525|delta/epsilon subdivisions,2X5GP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
k59_129685_1	1005048.CFU_1853	9.6e-64	213.0	COG2358@1|root,COG2358@2|Bacteria,1PNJV@1224|Proteobacteria,2VI8H@28216|Betaproteobacteria,473TS@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	transport system, periplasmic component	-	-	-	-	-	-	-	-	-	-	-	-	NMT1_3
k59_197943_1	443143.GM18_3468	5.3e-20	87.0	2DX02@1|root,342QW@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_31590_2	871963.Desdi_3521	1.34e-16	77.8	COG0378@1|root,COG0378@2|Bacteria,1TS00@1239|Firmicutes,248T1@186801|Clostridia,261IK@186807|Peptococcaceae	186801|Clostridia	KO	Hydrogenase accessory protein HypB	hypB	-	-	ko:K04652	-	-	-	-	ko00000,ko03110	-	-	-	cobW
k59_77277_1	1304885.AUEY01000026_gene3554	4.17e-45	156.0	COG1102@1|root,COG1102@2|Bacteria,1R4GX@1224|Proteobacteria,42QKV@68525|delta/epsilon subdivisions,2WJS2@28221|Deltaproteobacteria,2MPW7@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Cytidylate kinase-like family	-	-	-	-	-	-	-	-	-	-	-	-	Cytidylate_kin2
k59_190751_1	1249627.D779_0948	2.5e-22	99.4	COG1639@1|root,COG1639@2|Bacteria,1R8DI@1224|Proteobacteria,1SZC3@1236|Gammaproteobacteria,1X2JT@135613|Chromatiales	135613|Chromatiales	T	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	-	-	-	-	-	-	-	-	-	HDOD
k59_228761_1	1548905.A0A0A1IUM6_9CAUD	1.92e-26	110.0	4QHGF@10239|Viruses,4QQ9Z@28883|Caudovirales	28883|Caudovirales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_221330_1	880072.Desac_0834	2.41e-71	239.0	COG1145@1|root,COG1148@1|root,COG1145@2|Bacteria,COG1148@2|Bacteria,1QUM4@1224|Proteobacteria,42MPP@68525|delta/epsilon subdivisions,2WJ3U@28221|Deltaproteobacteria,2MQVU@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	4Fe-4S ferredoxin iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_20,Pyr_redox_2
k59_92244_1	177437.HRM2_15160	1.94e-104	329.0	COG0243@1|root,COG0437@1|root,COG0243@2|Bacteria,COG0437@2|Bacteria,1MU1B@1224|Proteobacteria,42NEG@68525|delta/epsilon subdivisions,2WKHA@28221|Deltaproteobacteria,2MMPS@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	actB	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_7,Molybdop_Fe4S4,Molybdopterin,Molydop_binding
k59_62145_1	1134912.AJTV01000023_gene2878	1.65e-68	226.0	COG1538@1|root,COG1538@2|Bacteria,1MUA8@1224|Proteobacteria,2TSN8@28211|Alphaproteobacteria,36Y6U@31993|Methylocystaceae	28211|Alphaproteobacteria	MU	Outer membrane efflux protein	oprN	-	-	ko:K18300,ko:K19593	-	M00641,M00769	-	-	ko00000,ko00002,ko01504,ko02000	1.B.17,2.A.6.2.34	-	-	OEP
k59_190769_1	880072.Desac_0306	8.95e-81	246.0	COG1521@1|root,COG1521@2|Bacteria,1MUYA@1224|Proteobacteria,42MVZ@68525|delta/epsilon subdivisions,2WJ3N@28221|Deltaproteobacteria,2MQTU@213462|Syntrophobacterales	28221|Deltaproteobacteria	F	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis	coaX	-	2.7.1.33	ko:K03525	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1986	Pan_kinase
k59_8880_1	335543.Sfum_1328	7.81e-49	168.0	COG1453@1|root,COG1453@2|Bacteria,1RAU3@1224|Proteobacteria,43A0M@68525|delta/epsilon subdivisions,2X9UN@28221|Deltaproteobacteria,2MS7U@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	PFAM aldo keto reductase	-	-	-	ko:K07079	-	-	-	-	ko00000	-	-	-	Aldo_ket_red
k59_228772_2	502025.Hoch_5266	1.84e-26	105.0	COG2515@1|root,COG2515@2|Bacteria,1MVYF@1224|Proteobacteria,42PWI@68525|delta/epsilon subdivisions,2WKFE@28221|Deltaproteobacteria,2YUTV@29|Myxococcales	28221|Deltaproteobacteria	E	Pyridoxal-phosphate dependent enzyme	-	-	4.4.1.15	ko:K05396	ko00270,map00270	-	R01874	RC00382	ko00000,ko00001,ko01000	-	-	-	PALP
k59_122682_1	293826.Amet_4705	4.01e-44	165.0	COG4666@1|root,COG4666@2|Bacteria,1TP0V@1239|Firmicutes,248AI@186801|Clostridia,36EPU@31979|Clostridiaceae	186801|Clostridia	S	TIGRFAM TRAP transporter, 4TM 12TM fusion protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF3394,DctM
k59_84625_1	224325.AF_1210	5.45e-56	186.0	COG3246@1|root,arCOG06125@2157|Archaea,2XUGZ@28890|Euryarchaeota	28890|Euryarchaeota	S	beta-keto acid cleavage enzyme	-	-	-	-	-	-	-	-	-	-	-	-	BKACE
k59_236429_1	768706.Desor_4144	2.06e-09	63.5	COG3290@1|root,COG3852@1|root,COG3290@2|Bacteria,COG3852@2|Bacteria,1TRH0@1239|Firmicutes,24C4K@186801|Clostridia,263WX@186807|Peptococcaceae	1239|Firmicutes	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	5TM-5TMR_LYT,HATPase_c,HisKA,PAS_3,PAS_4,PAS_9
k59_16399_1	1049564.TevJSym_ai00930	4.87e-84	265.0	COG4666@1|root,COG4666@2|Bacteria,1MUNB@1224|Proteobacteria,1RMH7@1236|Gammaproteobacteria,1J5X5@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Tripartite ATP-independent periplasmic transporter, DctM component	-	-	-	-	-	-	-	-	-	-	-	-	DctM
k59_206111_2	1049564.TevJSym_aa00830	4.32e-59	187.0	COG2930@1|root,COG2930@2|Bacteria,1RAIB@1224|Proteobacteria,1S5B7@1236|Gammaproteobacteria,1J71P@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Las17-binding protein actin regulator	-	-	-	-	-	-	-	-	-	-	-	-	Ysc84
k59_149001_2	1288494.EBAPG3_16530	2.82e-20	84.7	COG3157@1|root,COG3157@2|Bacteria,1RBTU@1224|Proteobacteria,2VS1N@28216|Betaproteobacteria	28216|Betaproteobacteria	S	type VI secretion system effector	-	-	-	ko:K11903	ko02025,ko03070,map02025,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko02044	-	-	-	T6SS_HCP
k59_210546_1	316067.Geob_3838	3.18e-51	179.0	COG0706@1|root,COG0706@2|Bacteria,1MV5M@1224|Proteobacteria,42MS8@68525|delta/epsilon subdivisions,2WJB6@28221|Deltaproteobacteria,43T3A@69541|Desulfuromonadales	28221|Deltaproteobacteria	U	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins	yidC	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP,YidC_periplas
k59_88762_1	401526.TcarDRAFT_0375	4.37e-20	89.4	COG0787@1|root,COG0787@2|Bacteria,1TNYY@1239|Firmicutes,4H1YC@909932|Negativicutes	909932|Negativicutes	M	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	alr	-	5.1.1.1	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N
k59_81522_1	999141.GME_10836	8.3e-12	68.2	COG0584@1|root,COG0584@2|Bacteria,1MU8H@1224|Proteobacteria,1SC8Y@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Membrane domain of glycerophosphoryl diester phosphodiesterase	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD,GPDPase_memb
k59_118771_1	1121405.dsmv_0560	4.45e-45	161.0	COG1614@1|root,COG1614@2|Bacteria,1MVI5@1224|Proteobacteria,42N9A@68525|delta/epsilon subdivisions,2WK4H@28221|Deltaproteobacteria,2MIRV@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM CO dehydrogenase acetyl-CoA synthase complex beta subunit	-	-	2.3.1.169	ko:K14138	ko00720,ko01120,ko01200,map00720,map01120,map01200	M00377	R08433,R10243	RC00004,RC00113,RC01144,RC02963,RC02964,RC02977	ko00000,ko00001,ko00002,ko01000	-	-	-	CdhC
k59_118771_2	335543.Sfum_2564	8.25e-60	197.0	COG1456@1|root,COG1456@2|Bacteria,1R4RE@1224|Proteobacteria,42M89@68525|delta/epsilon subdivisions,2WJVQ@28221|Deltaproteobacteria,2MR7F@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	CO dehydrogenase acetyl-CoA synthase delta subunit	-	-	2.1.1.245	ko:K00197	ko00680,ko00720,ko01120,ko01200,map00680,map00720,map01120,map01200	M00357,M00377,M00422	R09096,R10219,R10243	RC00004,RC00113,RC02977	ko00000,ko00001,ko00002,ko01000	-	-	-	CdhD,FeS
k59_58962_1	338963.Pcar_0647	6.3e-72	238.0	COG1674@1|root,COG1674@2|Bacteria,1MVPI@1224|Proteobacteria,42N4X@68525|delta/epsilon subdivisions,2WIPR@28221|Deltaproteobacteria,43S8B@69541|Desulfuromonadales	28221|Deltaproteobacteria	D	Ftsk_gamma	ftsK	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
k59_149010_1	1121405.dsmv_2220	4.27e-74	233.0	COG0042@1|root,COG0042@2|Bacteria,1QDJE@1224|Proteobacteria,42PCR@68525|delta/epsilon subdivisions,2WKBH@28221|Deltaproteobacteria,2MJ5C@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	-	-	-	-	-	-	-	-	-	-	-	-	Dus
k59_134723_1	1433126.BN938_0179	2.22e-88	273.0	COG0015@1|root,COG0015@2|Bacteria,4NFY8@976|Bacteroidetes,2FMYF@200643|Bacteroidia,22UZK@171550|Rikenellaceae	976|Bacteroidetes	F	Adenylosuccinate lyase C-terminal	purB	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ADSL_C,ASL_C,Lyase_1
k59_111660_1	1168289.AJKI01000030_gene1229	2.35e-40	141.0	COG0287@1|root,COG0287@2|Bacteria,4NIUC@976|Bacteroidetes,2FMD4@200643|Bacteroidia,3XJQ0@558415|Marinilabiliaceae	976|Bacteroidetes	E	Prephenate dehydrogenase	tyrA	-	1.3.1.12	ko:K00210	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00025	R01728	RC00125	ko00000,ko00001,ko00002,ko01000	-	-	-	PDH
k59_111660_2	391626.OAN307_c05870	1.49e-06	52.8	COG0077@1|root,COG0077@2|Bacteria,1MU60@1224|Proteobacteria,2TSUT@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Prephenate dehydratase	pheA	-	4.2.1.51	ko:K04518	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024	R00691,R01373	RC00360	ko00000,ko00001,ko00002,ko01000	-	-	-	PDT
k59_187998_1	671143.DAMO_1148	3.48e-117	352.0	COG0123@1|root,COG0123@2|Bacteria,2NP8V@2323|unclassified Bacteria	2|Bacteria	BQ	Histone deacetylase domain	acuC	-	-	ko:K04768	-	-	-	-	ko00000	-	-	-	Hist_deacetyl
k59_157254_1	1121405.dsmv_3580	5.83e-41	136.0	COG0186@1|root,COG0186@2|Bacteria,1MZIK@1224|Proteobacteria,42TNS@68525|delta/epsilon subdivisions,2WR6G@28221|Deltaproteobacteria,2MKWR@213118|Desulfobacterales	28221|Deltaproteobacteria	J	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA	rpsQ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02961	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S17
k59_157254_2	240016.ABIZ01000001_gene4070	8.9e-10	57.4	COG0255@1|root,COG0255@2|Bacteria,46TAV@74201|Verrucomicrobia,2IUWM@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Ribosomal L29 protein	-	-	-	ko:K02904	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L29
k59_157254_3	1121405.dsmv_3582	2.04e-59	185.0	COG0197@1|root,COG0197@2|Bacteria,1RA0Z@1224|Proteobacteria,42QW5@68525|delta/epsilon subdivisions,2WP71@28221|Deltaproteobacteria,2MJKH@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs	rplP	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904	-	ko:K02878	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L16
k59_27719_1	1121405.dsmv_1857	4.02e-35	130.0	28VGR@1|root,2ZHJ8@2|Bacteria,1RBS0@1224|Proteobacteria,42QZB@68525|delta/epsilon subdivisions,2WN03@28221|Deltaproteobacteria,2MJPZ@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_73863_1	1499967.BAYZ01000122_gene3388	6.49e-30	120.0	COG0760@1|root,COG0760@2|Bacteria,2NPQV@2323|unclassified Bacteria	2|Bacteria	O	PPIC-type PPIASE domain	surA	-	5.2.1.8	ko:K02597,ko:K03769,ko:K03771	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N,SurA_N_3
k59_135085_1	96561.Dole_0398	2.12e-64	205.0	COG0667@1|root,COG0667@2|Bacteria	2|Bacteria	C	Aldo Keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red,HEAT_2,TetR_C_7,TetR_N
k59_135087_1	1205680.CAKO01000002_gene3000	5.98e-11	70.1	COG2114@1|root,COG2114@2|Bacteria,1RBTC@1224|Proteobacteria,2TV5V@28211|Alphaproteobacteria,2JPH4@204441|Rhodospirillales	204441|Rhodospirillales	T	Adenylate cyclase	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc,HAMP
k59_225434_1	1283300.ATXB01000001_gene2236	3.07e-56	189.0	COG3344@1|root,COG3344@2|Bacteria,1MVI1@1224|Proteobacteria,1RQP7@1236|Gammaproteobacteria,1XFDE@135618|Methylococcales	135618|Methylococcales	L	PFAM RNA-directed DNA polymerase (reverse transcriptase)	-	-	-	-	-	-	-	-	-	-	-	-	GIIM,RVT_1
k59_89239_1	1002672.SAR11G3_00190	7.04e-119	353.0	COG1840@1|root,COG1840@2|Bacteria,1MWWI@1224|Proteobacteria,2VF0S@28211|Alphaproteobacteria,4BTD5@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	P	Bacterial extracellular solute-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_6
k59_74110_1	1265505.ATUG01000002_gene2074	1.53e-116	356.0	COG1109@1|root,COG1109@2|Bacteria,1QUGD@1224|Proteobacteria,43BUU@68525|delta/epsilon subdivisions,2WKYP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	phosphoglucomutase phosphomannomutase alpha beta alpha domain I	-	-	5.4.2.2,5.4.2.8	ko:K01835,ko:K01840	ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00114,M00549	R00959,R01057,R01818,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
k59_59302_1	1121405.dsmv_2841	8.23e-59	186.0	COG4747@1|root,COG4747@2|Bacteria,1RDCG@1224|Proteobacteria,42RTD@68525|delta/epsilon subdivisions,2WQBM@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM amino acid-binding ACT domain protein	-	-	-	-	-	-	-	-	-	-	-	-	ACT
k59_142656_1	335543.Sfum_3024	4.16e-98	303.0	COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,42M1X@68525|delta/epsilon subdivisions,2WJA2@28221|Deltaproteobacteria,2MQ8Y@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	Thiamine pyrophosphate enzyme, central	ilvB	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
k59_240569_1	857293.CAAU_1416	1.08e-35	134.0	COG3267@1|root,COG3267@2|Bacteria,1TRGM@1239|Firmicutes,24EPV@186801|Clostridia,36HUB@31979|Clostridiaceae	186801|Clostridia	U	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22
k59_50985_2	933262.AXAM01000006_gene1880	1.15e-47	164.0	COG0477@1|root,COG2814@2|Bacteria,1MWFH@1224|Proteobacteria,42QX9@68525|delta/epsilon subdivisions,2WKS8@28221|Deltaproteobacteria,2MIGQ@213118|Desulfobacterales	28221|Deltaproteobacteria	EGP	Major Facilitator Superfamily	-	-	-	ko:K08224	-	-	-	-	ko00000,ko02000	2.A.1.36	-	-	MFS_1
k59_112144_1	1121405.dsmv_2534	5.76e-63	212.0	COG0247@1|root,COG0247@2|Bacteria,1MUMH@1224|Proteobacteria,42MIV@68525|delta/epsilon subdivisions,2WJ5X@28221|Deltaproteobacteria,2MIC5@213118|Desulfobacterales	28221|Deltaproteobacteria	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_10,Fer4_8
k59_179741_1	1162668.LFE_1946	6.71e-33	124.0	COG4589@1|root,COG4589@2|Bacteria,3J1FV@40117|Nitrospirae	40117|Nitrospirae	I	Cytidylyltransferase family	-	-	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
k59_203165_1	335543.Sfum_1329	5.37e-63	211.0	COG0348@1|root,COG1143@1|root,COG1152@1|root,COG0348@2|Bacteria,COG1143@2|Bacteria,COG1152@2|Bacteria,1MY5M@1224|Proteobacteria,43BPV@68525|delta/epsilon subdivisions,2WJVS@28221|Deltaproteobacteria,2MSKF@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_5,Fer4_7
k59_135104_1	335541.Swol_1785	8.48e-42	144.0	COG0634@1|root,COG0634@2|Bacteria,1V1C9@1239|Firmicutes,24FR4@186801|Clostridia,42JX1@68298|Syntrophomonadaceae	186801|Clostridia	F	Belongs to the purine pyrimidine phosphoribosyltransferase family	hpt	-	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
k59_210902_1	1322246.BN4_11939	4.32e-16	74.7	29JB6@1|root,3068N@2|Bacteria,1Q03W@1224|Proteobacteria,436C4@68525|delta/epsilon subdivisions,2X9HH@28221|Deltaproteobacteria,2MDPA@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Domain of unknown function (DUF4389)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4389
k59_240594_1	269799.Gmet_0354	7.61e-45	165.0	COG5009@1|root,COG5009@2|Bacteria,1MU5A@1224|Proteobacteria,42MJB@68525|delta/epsilon subdivisions,2WIXF@28221|Deltaproteobacteria,43TJB@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	PFAM glycosyl transferase family 51	mrcA	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	iAF987.Gmet_0354	PCB_OB,Transgly,Transpeptidase
k59_43252_1	1121405.dsmv_1987	4.4e-49	162.0	COG0839@1|root,COG0839@2|Bacteria,1MWJV@1224|Proteobacteria,42SDZ@68525|delta/epsilon subdivisions,2WPXS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM NADH-ubiquinone plastoquinone oxidoreductase, chain 6	nuoJ-2	-	1.6.5.3	ko:K00339	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q3
k59_43252_2	335543.Sfum_1938	1.51e-15	71.2	COG0713@1|root,COG0713@2|Bacteria,1RH0S@1224|Proteobacteria,42VAT@68525|delta/epsilon subdivisions,2WRE5@28221|Deltaproteobacteria,2MSHN@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoK-2	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0050136,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204	1.6.5.3	ko:K00340	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q2
k59_194843_1	2340.JV46_07840	3.84e-47	164.0	COG1575@1|root,COG1575@2|Bacteria,1QJ69@1224|Proteobacteria,1TH3V@1236|Gammaproteobacteria,1J61G@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	H	UbiA prenyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	UbiA
k59_172641_1	1158345.JNLL01000001_gene1876	3.77e-56	199.0	COG2217@1|root,COG2217@2|Bacteria,2G4TD@200783|Aquificae	200783|Aquificae	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,Hydrolase
k59_89254_1	335543.Sfum_1611	1.15e-07	52.8	2E6FN@1|root,319CM@2|Bacteria,1Q2BN@1224|Proteobacteria,437Y4@68525|delta/epsilon subdivisions,2X382@28221|Deltaproteobacteria,2MSCF@213462|Syntrophobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_89254_2	1004785.AMBLS11_00070	4.39e-06	47.4	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,1RNBG@1236|Gammaproteobacteria,465DD@72275|Alteromonadaceae	1236|Gammaproteobacteria	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
k59_240605_1	1232410.KI421423_gene1869	3.68e-97	294.0	COG0183@1|root,COG0183@2|Bacteria,1MXYM@1224|Proteobacteria,42PAF@68525|delta/epsilon subdivisions,2WM45@28221|Deltaproteobacteria,43SY0@69541|Desulfuromonadales	28221|Deltaproteobacteria	I	Thiolase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Thiolase_C,Thiolase_N
k59_89262_1	1121403.AUCV01000001_gene989	3.3e-05	45.1	COG1977@1|root,COG1977@2|Bacteria	2|Bacteria	H	Mo-molybdopterin cofactor metabolic process	moaD	-	-	ko:K03154	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS,Ub-Mut7C
k59_89262_2	207559.Dde_2459	1.59e-09	61.2	COG0476@1|root,COG0476@2|Bacteria,1MW7H@1224|Proteobacteria,42Q7U@68525|delta/epsilon subdivisions,2WPC0@28221|Deltaproteobacteria,2MAT7@213115|Desulfovibrionales	28221|Deltaproteobacteria	H	PFAM UBA THIF-type NAD FAD binding	moeB	-	2.7.7.73	ko:K03148	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07459	RC00043	ko00000,ko00001,ko01000	-	-	-	ThiF
k59_127382_1	1232437.KL662031_gene2518	1.22e-57	187.0	COG1152@1|root,COG1152@2|Bacteria,1R2X2@1224|Proteobacteria,43DHE@68525|delta/epsilon subdivisions,2X8P7@28221|Deltaproteobacteria,2MK7W@213118|Desulfobacterales	28221|Deltaproteobacteria	C	4Fe-4S ferredoxin iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_194858_1	335543.Sfum_2348	1.98e-84	261.0	COG0438@1|root,COG0438@2|Bacteria,1MYTB@1224|Proteobacteria,42MCA@68525|delta/epsilon subdivisions,2WJVX@28221|Deltaproteobacteria,2MQT9@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	PFAM Glycosyl transferases group 1	-	-	2.4.1.245	ko:K13057	ko00500,ko01100,map00500,map01100	-	R08946,R10525,R11306	RC00005,RC00049,RC02748	ko00000,ko00001,ko01000	-	GT4	-	Glycos_transf_1
k59_36421_1	1121396.KB893074_gene3024	2.08e-59	203.0	COG0021@1|root,COG0021@2|Bacteria,1MUEY@1224|Proteobacteria,42M80@68525|delta/epsilon subdivisions,2WINJ@28221|Deltaproteobacteria,2MHY9@213118|Desulfobacterales	28221|Deltaproteobacteria	G	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate	tkt	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
k59_112169_1	386456.JQKN01000001_gene2221	1.07e-09	63.2	COG1123@1|root,arCOG00185@2157|Archaea,2Y7KQ@28890|Euryarchaeota,23NTU@183925|Methanobacteria	183925|Methanobacteria	E	TIGRFAM Methyl coenzyme M reductase system, component A2	-	-	-	ko:K00400	ko00680,ko01100,ko01120,map00680,map01100,map01120	-	-	-	ko00000,ko00001	-	-	-	ABC_tran
k59_172658_1	933262.AXAM01000015_gene115	6.49e-84	261.0	COG0436@1|root,COG0436@2|Bacteria,1QW10@1224|Proteobacteria,42MQA@68525|delta/epsilon subdivisions,2WJDK@28221|Deltaproteobacteria,2MJ7D@213118|Desulfobacterales	28221|Deltaproteobacteria	E	PFAM aminotransferase class I and II	bamJ	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
k59_188292_1	1541960.KQ78_01293	5.8e-82	273.0	COG3299@1|root,COG3497@1|root,COG3299@2|Bacteria,COG3497@2|Bacteria	2|Bacteria	S	Phage tail sheath protein subtilisin-like domain	-	-	3.2.1.78	ko:K01218,ko:K06907	ko00051,ko02024,map00051,map02024	-	R01332	RC00467	ko00000,ko00001,ko01000	-	GH26	-	Baseplate_J,PA14,Phage_sheath_1,Phage_sheath_1C,fn3
k59_210926_1	1125863.JAFN01000001_gene1563	3.55e-15	73.9	COG1305@1|root,COG1305@2|Bacteria,1R9XR@1224|Proteobacteria,42QTZ@68525|delta/epsilon subdivisions,2WMV1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	PFAM transglutaminase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
k59_210926_2	543526.Htur_1468	8.51e-10	64.3	arCOG02703@1|root,arCOG02703@2157|Archaea,2XV0I@28890|Euryarchaeota,23SUR@183963|Halobacteria	183963|Halobacteria	Q	Methyltransferase type 11	aknG	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25,Methyltransf_31
k59_172662_1	1499967.BAYZ01000040_gene2249	1.66e-52	174.0	COG2230@1|root,COG2230@2|Bacteria	2|Bacteria	M	cyclopropane-fatty-acyl-phospholipid synthase	cfa	-	2.1.1.79	ko:K00574	-	-	-	-	ko00000,ko01000	-	-	-	CMAS
k59_96906_1	926562.Oweho_3325	1.1e-33	130.0	COG0577@1|root,COG0577@2|Bacteria,4NEBD@976|Bacteroidetes,1HY2A@117743|Flavobacteriia	976|Bacteroidetes	V	ABC-type antimicrobial peptide transport system, permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
k59_51028_1	1316927.ATKI01000034_gene4592	1.75e-75	248.0	COG1033@1|root,COG1033@2|Bacteria,1MUE1@1224|Proteobacteria,1SKJU@1236|Gammaproteobacteria,1YSB6@136843|Pseudomonas fluorescens group	1236|Gammaproteobacteria	S	MMPL family	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
k59_233846_1	1121396.KB893100_gene4319	3.25e-137	429.0	COG0493@1|root,COG1148@1|root,COG0493@2|Bacteria,COG1148@2|Bacteria,1QUM4@1224|Proteobacteria,42MPP@68525|delta/epsilon subdivisions,2WJ3U@28221|Deltaproteobacteria,2MIA4@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_20,Fer4_7,Pyr_redox_2
k59_188305_1	575540.Isop_2181	7.24e-22	101.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF2723,PMT_2
k59_96909_1	330214.NIDE4145	3.72e-74	236.0	COG1004@1|root,COG1004@2|Bacteria,3J0EJ@40117|Nitrospirae	40117|Nitrospirae	C	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	-	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
k59_89292_1	1232437.KL662019_gene628	9.49e-50	166.0	COG3385@1|root,COG3385@2|Bacteria,1NUI6@1224|Proteobacteria,42ZJ8@68525|delta/epsilon subdivisions,2WV27@28221|Deltaproteobacteria,2MND0@213118|Desulfobacterales	28221|Deltaproteobacteria	L	transposase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_89292_2	1232437.KL662019_gene629	2.55e-60	189.0	COG5659@1|root,COG5659@2|Bacteria	2|Bacteria	L	transposition	-	-	-	-	-	-	-	-	-	-	-	-	DDE_5,SIR2_2
k59_240659_1	426114.THI_0881	5.13e-48	166.0	COG0484@1|root,COG0484@2|Bacteria,1MUZ4@1224|Proteobacteria,2VHMU@28216|Betaproteobacteria,1KJTC@119065|unclassified Burkholderiales	28216|Betaproteobacteria	O	heat shock protein DnaJ	cbpA	-	-	ko:K05516	-	-	-	-	ko00000,ko03036,ko03110	-	-	-	DnaJ,DnaJ_C
k59_142683_1	1499967.BAYZ01000154_gene1502	8.17e-43	150.0	COG5421@1|root,COG5421@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_66194_1	1122194.AUHU01000004_gene1515	2.36e-19	92.4	COG1450@1|root,COG1450@2|Bacteria,1MVNC@1224|Proteobacteria,1RQGJ@1236|Gammaproteobacteria,464TU@72275|Alteromonadaceae	1236|Gammaproteobacteria	NU	pilus (MSHA type) biogenesis protein MshL	mshL	-	-	ko:K12282	-	-	-	-	ko00000,ko02044	-	-	-	STN,Secretin,Secretin_N_2
k59_89300_1	1235800.C819_04274	3.42e-54	190.0	COG0445@1|root,COG0445@2|Bacteria,1TQ4B@1239|Firmicutes,247U2@186801|Clostridia,27JRZ@186928|unclassified Lachnospiraceae	186801|Clostridia	D	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34	gidA	-	-	ko:K03495	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko03016,ko03036	-	-	-	GIDA,GIDA_assoc
k59_233855_1	246197.MXAN_5605	1.61e-90	280.0	COG0772@1|root,COG0772@2|Bacteria,1MVDB@1224|Proteobacteria,42MG2@68525|delta/epsilon subdivisions,2WJ01@28221|Deltaproteobacteria,2YTX5@29|Myxococcales	28221|Deltaproteobacteria	D	Belongs to the SEDS family	ftsW	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
k59_43287_1	1121448.DGI_2420	1.75e-49	172.0	COG0504@1|root,COG0504@2|Bacteria,1MUIT@1224|Proteobacteria,42MEU@68525|delta/epsilon subdivisions,2WJ0F@28221|Deltaproteobacteria,2M91M@213115|Desulfovibrionales	28221|Deltaproteobacteria	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1276	CTP_synth_N,GATase
k59_43287_2	880072.Desac_2093	3.92e-114	336.0	COG2877@1|root,COG2877@2|Bacteria,1MV91@1224|Proteobacteria,42M61@68525|delta/epsilon subdivisions,2WIXU@28221|Deltaproteobacteria,2MQA2@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	PFAM DAHP synthetase I	kdsA	-	2.5.1.55	ko:K01627	ko00540,ko01100,map00540,map01100	M00063	R03254	RC00435	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	DAHP_synth_1
k59_142691_1	1250278.JQNQ01000001_gene2906	3.77e-36	136.0	COG3547@1|root,COG3547@2|Bacteria,4NIKY@976|Bacteroidetes,1HZCU@117743|Flavobacteriia	976|Bacteroidetes	L	Transposase IS116 IS110 IS902	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_203207_1	1121413.JMKT01000011_gene2318	3.95e-29	117.0	29UKS@1|root,30FY7@2|Bacteria,1RGKW@1224|Proteobacteria,430C2@68525|delta/epsilon subdivisions,2WW6K@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_132219_1	118166.JH976537_gene2038	3.05e-69	216.0	COG2818@1|root,COG2818@2|Bacteria,1G5Y1@1117|Cyanobacteria,1HF1X@1150|Oscillatoriales	1117|Cyanobacteria	L	Methyladenine glycosylase	-	-	3.2.2.20	ko:K01246	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Adenine_glyco
k59_208239_1	1499967.BAYZ01000115_gene2932	9.37e-83	269.0	COG0112@1|root,COG0404@1|root,COG0112@2|Bacteria,COG0404@2|Bacteria,2NP28@2323|unclassified Bacteria	2|Bacteria	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	gcvT	GO:0001505,GO:0003674,GO:0003824,GO:0004047,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005960,GO:0006082,GO:0006520,GO:0006544,GO:0006546,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008483,GO:0009056,GO:0009063,GO:0009069,GO:0009071,GO:0009987,GO:0016054,GO:0016740,GO:0016741,GO:0016769,GO:0017144,GO:0019464,GO:0019752,GO:0032259,GO:0032991,GO:0042133,GO:0042135,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606,GO:1902494,GO:1990204	2.1.2.1,2.1.2.10,2.2.1.8	ko:K00600,ko:K00605,ko:K18847	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R01221,R02300,R04125,R09099	RC00022,RC00069,RC00112,RC00183,RC01583,RC02834,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C,SHMT
k59_192718_1	1401065.HMPREF2130_01720	7.81e-05	48.5	COG0621@1|root,COG0621@2|Bacteria,1MURS@1224|Proteobacteria,2VHQM@28216|Betaproteobacteria,3T2I4@506|Alcaligenaceae	28216|Betaproteobacteria	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
k59_192718_2	933262.AXAM01000029_gene2735	7.43e-35	123.0	COG1259@1|root,COG1259@2|Bacteria,1RFFV@1224|Proteobacteria,42SCI@68525|delta/epsilon subdivisions,2WPWT@28221|Deltaproteobacteria,2MJT1@213118|Desulfobacterales	28221|Deltaproteobacteria	O	Bifunctional nuclease	-	-	-	ko:K08999	-	-	-	-	ko00000	-	-	-	DNase-RNase
k59_185632_1	484018.BACPLE_00584	1.54e-22	102.0	COG0116@1|root,COG0116@2|Bacteria,4NFJM@976|Bacteroidetes,2FMNN@200643|Bacteroidia,4AMR4@815|Bacteroidaceae	976|Bacteroidetes	L	Belongs to the methyltransferase superfamily	rlmL	-	-	ko:K07444	-	-	-	-	ko00000,ko01000	-	-	-	THUMP,UPF0020
k59_48618_1	555079.Toce_1953	7.07e-40	147.0	COG4584@1|root,COG4584@2|Bacteria,1TR5X@1239|Firmicutes,25D02@186801|Clostridia,42FJ4@68295|Thermoanaerobacterales	186801|Clostridia	L	COGs COG4584 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	HTH_23,Mu-transpos_C,rve
k59_86478_1	439235.Dalk_0513	3.25e-57	201.0	COG0664@1|root,COG1033@1|root,COG2199@1|root,COG0664@2|Bacteria,COG1033@2|Bacteria,COG2199@2|Bacteria,1MUE1@1224|Proteobacteria,42ME2@68525|delta/epsilon subdivisions,2WJRI@28221|Deltaproteobacteria,2MJQ7@213118|Desulfobacterales	28221|Deltaproteobacteria	K	MMPL family	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	GGDEF,LolA_like,MMPL,cNMP_binding
k59_10970_1	335543.Sfum_3369	1.85e-44	169.0	COG4581@1|root,COG4581@2|Bacteria,1QUPR@1224|Proteobacteria,42NSH@68525|delta/epsilon subdivisions,2WKD7@28221|Deltaproteobacteria,2MQUA@213462|Syntrophobacterales	28221|Deltaproteobacteria	L	DSHCT	-	-	-	-	-	-	-	-	-	-	-	-	DEAD,DSHCT,DUF3516,Helicase_C
k59_124954_2	223926.28807474	9.39e-21	91.3	COG0628@1|root,COG0628@2|Bacteria,1MVX7@1224|Proteobacteria,1RN5Z@1236|Gammaproteobacteria,1XT37@135623|Vibrionales	135623|Vibrionales	S	permease	VP2476	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
k59_41126_1	471852.Tcur_0154	1.5e-27	108.0	COG2197@1|root,COG2197@2|Bacteria,2GJHH@201174|Actinobacteria,4EHZ1@85012|Streptosporangiales	201174|Actinobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	ko:K07696	ko02020,map02020	M00483	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
k59_162487_1	335543.Sfum_3207	5.24e-16	77.0	COG0115@1|root,COG0115@2|Bacteria,1MVB0@1224|Proteobacteria,42PRS@68525|delta/epsilon subdivisions,2WK0H@28221|Deltaproteobacteria	28221|Deltaproteobacteria	EH	PFAM aminotransferase, class IV	-	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
k59_162487_2	644282.Deba_1943	1.29e-79	243.0	COG1611@1|root,COG1611@2|Bacteria,1MU6N@1224|Proteobacteria,42P56@68525|delta/epsilon subdivisions,2WK5J@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Belongs to the LOG family	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
k59_230873_1	589865.DaAHT2_2463	4.64e-53	184.0	COG5421@1|root,COG5421@2|Bacteria,1R7NE@1224|Proteobacteria,42M25@68525|delta/epsilon subdivisions,2WKHV@28221|Deltaproteobacteria,2MJVY@213118|Desulfobacterales	28221|Deltaproteobacteria	L	IMG reference gene	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
k59_79258_1	765177.Desmu_0401	2.57e-06	55.1	COG4231@1|root,arCOG01609@2157|Archaea,2XPY7@28889|Crenarchaeota	28889|Crenarchaeota	C	Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates	-	-	1.2.7.8	ko:K00179	-	-	-	-	br01601,ko00000,ko01000	-	-	-	Fer4,POR_N,TPP_enzyme_C
k59_132232_2	1410626.JHXB01000016_gene1751	6.78e-29	114.0	COG3842@1|root,COG3842@2|Bacteria,1TP2M@1239|Firmicutes,247JR@186801|Clostridia,27KGX@186928|unclassified Lachnospiraceae	186801|Clostridia	E	ATPases associated with a variety of cellular activities	cysA	-	3.6.3.25	ko:K02045,ko:K02052	ko00920,ko02010,ko02024,map00920,map02010,map02024	M00185,M00193	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.11,3.A.1.6.1,3.A.1.6.3	-	-	ABC_tran,TOBE_2
k59_147137_1	1121405.dsmv_0068	3.43e-20	89.0	COG0467@1|root,COG1396@1|root,COG0467@2|Bacteria,COG1396@2|Bacteria,1PE60@1224|Proteobacteria,42NFD@68525|delta/epsilon subdivisions,2WK1C@28221|Deltaproteobacteria,2MIB3@213118|Desulfobacterales	28221|Deltaproteobacteria	K	Cupin 2 conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,HTH_3
k59_147137_2	314230.DSM3645_16995	2.48e-16	80.9	COG2844@1|root,COG2844@2|Bacteria,2IXR0@203682|Planctomycetes	203682|Planctomycetes	H	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen	glnD	-	2.7.7.59	ko:K00990	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	-	-	-	DUF294,GlnD_UR_UTase,HD
k59_192719_1	1125863.JAFN01000001_gene3333	3.43e-38	144.0	COG1253@1|root,COG1253@2|Bacteria,1MV3P@1224|Proteobacteria,42N97@68525|delta/epsilon subdivisions,2WJV1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM CBS domain	-	-	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	CBS,CorC_HlyC,DUF21
k59_192719_2	1121447.JONL01000002_gene1773	7.17e-06	47.0	2EJAZ@1|root,33D23@2|Bacteria,1NGTE@1224|Proteobacteria,42WZV@68525|delta/epsilon subdivisions,2WSJH@28221|Deltaproteobacteria,2MDVR@213115|Desulfovibrionales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_124962_1	706587.Desti_1743	1.15e-63	212.0	COG3829@1|root,COG4191@1|root,COG3829@2|Bacteria,COG4191@2|Bacteria,1MY12@1224|Proteobacteria,42PID@68525|delta/epsilon subdivisions,2WJVW@28221|Deltaproteobacteria,2MRHK@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_9
k59_86494_2	634497.HAH_2126	1.46e-10	64.7	arCOG03850@1|root,arCOG03850@2157|Archaea,2XYUB@28890|Euryarchaeota,23ZXM@183963|Halobacteria	183963|Halobacteria	S	Cephalosporin hydroxylase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_24
k59_215420_1	555500.I215_09017	8.64e-90	281.0	COG2272@1|root,COG2272@2|Bacteria,4NF5N@976|Bacteroidetes,1HZ06@117743|Flavobacteriia	976|Bacteroidetes	I	Belongs to the type-B carboxylesterase lipase family	-	-	-	ko:K03929	-	-	-	-	ko00000,ko01000	-	CE10	-	COesterase
k59_48637_1	1499967.BAYZ01000016_gene6508	6.16e-91	280.0	COG2203@1|root,COG3437@1|root,COG2203@2|Bacteria,COG3437@2|Bacteria,2NQE8@2323|unclassified Bacteria	2|Bacteria	T	HD domain	-	-	-	ko:K07814	-	-	-	-	ko00000,ko02022	-	-	-	GAF,GAF_2,HD,HD_5
k59_64013_1	376733.IT41_15810	3.8e-14	75.5	COG0741@1|root,COG0741@2|Bacteria,1MZ4X@1224|Proteobacteria,2TU56@28211|Alphaproteobacteria,2PWKS@265|Paracoccus	28211|Alphaproteobacteria	M	Lytic transglycosylase	-	-	-	-	-	-	-	-	-	-	-	-	SLT
k59_155166_2	1519439.JPJG01000059_gene1907	2.77e-30	115.0	COG4725@1|root,COG4725@2|Bacteria,1TSJV@1239|Firmicutes,248X5@186801|Clostridia	186801|Clostridia	KT	Belongs to the MT-A70-like family	-	-	-	-	-	-	-	-	-	-	-	-	MT-A70
k59_192725_2	926569.ANT_27030	4.09e-12	66.2	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,2G5Q5@200795|Chloroflexi	200795|Chloroflexi	EU	PFAM peptidase S9 prolyl oligopeptidase active site domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
k59_177565_1	1121405.dsmv_1008	3.43e-49	176.0	COG2766@1|root,COG2766@2|Bacteria,1NG7R@1224|Proteobacteria,42P8B@68525|delta/epsilon subdivisions,2WJIU@28221|Deltaproteobacteria,2MIAY@213118|Desulfobacterales	28221|Deltaproteobacteria	T	PrkA serine protein kinase C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_PrkA,PrkA
k59_25895_1	933262.AXAM01000088_gene298	4.49e-125	371.0	COG2605@1|root,COG2605@2|Bacteria,1QW1A@1224|Proteobacteria,42N0X@68525|delta/epsilon subdivisions,2WJYP@28221|Deltaproteobacteria,2MHZ0@213118|Desulfobacterales	28221|Deltaproteobacteria	S	PFAM GHMP kinase	-	-	2.7.1.168	ko:K07031	ko00540,map00540	-	R09770	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
k59_208267_1	933262.AXAM01000020_gene23	1.03e-60	201.0	COG0342@1|root,COG0342@2|Bacteria,1MV5U@1224|Proteobacteria,42M6V@68525|delta/epsilon subdivisions,2WJCI@28221|Deltaproteobacteria,2MHS8@213118|Desulfobacterales	28221|Deltaproteobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
k59_170031_1	1293054.HSACCH_01467	8.85e-05	50.4	COG0215@1|root,COG0215@2|Bacteria,1TP9D@1239|Firmicutes,247KS@186801|Clostridia,3WAEM@53433|Halanaerobiales	186801|Clostridia	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	-	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e,tRNA-synt_1g
k59_230893_1	1121405.dsmv_3019	9.79e-31	117.0	COG0803@1|root,COG0803@2|Bacteria,1MVW9@1224|Proteobacteria,42MBX@68525|delta/epsilon subdivisions,2WJYG@28221|Deltaproteobacteria,2MJBW@213118|Desulfobacterales	28221|Deltaproteobacteria	P	PFAM periplasmic solute binding protein	-	-	-	ko:K09815	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ZnuA
k59_200433_1	28072.Nos7524_2009	8.95e-09	63.5	COG2304@1|root,COG3209@1|root,COG4932@1|root,COG2304@2|Bacteria,COG3209@2|Bacteria,COG4932@2|Bacteria,1GPZZ@1117|Cyanobacteria,1HJUW@1161|Nostocales	1117|Cyanobacteria	M	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	-	-	-	-	-	-	-	-	-	-	-	-	RHS_repeat,VWA
k59_56537_1	1122612.AUBA01000003_gene1573	2.11e-18	87.8	COG1253@1|root,COG1253@2|Bacteria,1MV3P@1224|Proteobacteria,2TVFA@28211|Alphaproteobacteria,2K03F@204457|Sphingomonadales	204457|Sphingomonadales	S	COG1253 Hemolysins and related proteins containing CBS domains	-	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC
k59_124973_1	1038860.AXAP01000002_gene4850	3.18e-107	328.0	COG1574@1|root,COG1574@2|Bacteria,1MWP2@1224|Proteobacteria,2TXAW@28211|Alphaproteobacteria,3JWHS@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
k59_200436_1	671143.DAMO_0070	7.86e-62	202.0	COG4974@1|root,COG4974@2|Bacteria,2NP4H@2323|unclassified Bacteria	2|Bacteria	L	Phage integrase, N-terminal SAM-like domain	xerC	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K03733,ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
k59_155172_1	311424.DhcVS_403	3.23e-46	159.0	COG0287@1|root,COG0287@2|Bacteria,2GAKF@200795|Chloroflexi,34CNR@301297|Dehalococcoidia	301297|Dehalococcoidia	C	Prephenate dehydrogenase	-	-	1.3.1.12	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00025	R01728	RC00125	ko00000,ko00001,ko00002,ko01000	-	-	-	PDH
k59_94269_1	926569.ANT_17730	2.76e-19	83.6	COG4109@1|root,COG4109@2|Bacteria	2|Bacteria	K	DRTGG domain	-	-	-	-	-	-	-	-	-	-	-	-	DRTGG
k59_94269_2	177437.HRM2_16560	1.03e-39	136.0	COG2172@1|root,COG2172@2|Bacteria,1MZIF@1224|Proteobacteria,42WMC@68525|delta/epsilon subdivisions,2WSA5@28221|Deltaproteobacteria,2MMAR@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Histidine kinase-like ATPase domain	-	-	2.7.11.1	ko:K17752	-	-	-	-	ko00000,ko01000,ko01001,ko03021	-	-	-	HATPase_c,HATPase_c_2
k59_94269_3	177437.HRM2_16550	9.44e-06	49.7	COG1145@1|root,COG2000@1|root,COG4624@1|root,COG1145@2|Bacteria,COG2000@2|Bacteria,COG4624@2|Bacteria,1N8C8@1224|Proteobacteria,42WQ6@68525|delta/epsilon subdivisions,2WRHJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Iron only hydrogenase large subunit, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	FeS,Fe_hyd_lg_C,Fer4
k59_147150_1	1121434.AULY01000010_gene2425	1.13e-94	310.0	COG0574@1|root,COG3848@1|root,COG0574@2|Bacteria,COG3848@2|Bacteria,1QFX3@1224|Proteobacteria,42PIP@68525|delta/epsilon subdivisions,2WKWI@28221|Deltaproteobacteria,2MG9J@213115|Desulfovibrionales	28221|Deltaproteobacteria	G	PFAM Pyruvate phosphate dikinase, PEP pyruvate-binding	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PPDK_N
k59_147150_2	1304872.JAGC01000009_gene485	1.95e-21	91.3	2AFUA@1|root,315WQ@2|Bacteria,1NHGB@1224|Proteobacteria,42TSA@68525|delta/epsilon subdivisions,2WQKD@28221|Deltaproteobacteria,2M9ZQ@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Putative transmembrane protein (Alph_Pro_TM)	-	-	-	-	-	-	-	-	-	-	-	-	Alph_Pro_TM
k59_56544_1	697303.Thewi_1529	5.18e-84	255.0	COG0235@1|root,COG0235@2|Bacteria,1TPDV@1239|Firmicutes,248KI@186801|Clostridia,42GCS@68295|Thermoanaerobacterales	186801|Clostridia	G	PFAM class II aldolase adducin family protein	fucA	-	4.1.2.17,5.1.3.4	ko:K01628,ko:K03077	ko00040,ko00051,ko00053,ko01100,ko01120,map00040,map00051,map00053,map01100,map01120	M00550	R02262,R05850	RC00603,RC00604,RC01479	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldolase_II
k59_71481_1	1121405.dsmv_2098	1.52e-46	162.0	COG0795@1|root,COG0795@2|Bacteria,1MVW3@1224|Proteobacteria	1224|Proteobacteria	S	Permease, YjgP YjgQ family	lptG	-	-	ko:K11720	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
k59_79722_1	1121413.JMKT01000008_gene1518	1.86e-08	54.3	COG0642@1|root,COG2205@2|Bacteria,1QHXX@1224|Proteobacteria,42NW1@68525|delta/epsilon subdivisions,2WJUF@28221|Deltaproteobacteria,2M85B@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	PFAM ATP-binding region ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
k59_200907_1	398527.Bphyt_4399	2.22e-23	99.8	2EHMJ@1|root,33BDB@2|Bacteria,1RG1S@1224|Proteobacteria,2W287@28216|Betaproteobacteria,1K3X0@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Domain of unknown function (DUF4410)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4410
k59_3230_1	1121405.dsmv_0146	1.64e-29	119.0	COG0484@1|root,COG0484@2|Bacteria,1R72H@1224|Proteobacteria,42NCE@68525|delta/epsilon subdivisions,2WKDN@28221|Deltaproteobacteria,2MKP5@213118|Desulfobacterales	28221|Deltaproteobacteria	O	Class III cytochrome C family	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_CIII
k59_231417_1	1297534.CAUJ01000008_gene628	1.29e-05	50.8	COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,1TS9U@1239|Firmicutes,4H9M4@91061|Bacilli	91061|Bacilli	S	Competence protein ComEC	comEC	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131,Lactamase_B
k59_192988_1	941449.dsx2_0235	4.07e-64	206.0	COG1077@1|root,COG1077@2|Bacteria,1R875@1224|Proteobacteria,42NJK@68525|delta/epsilon subdivisions,2WKDI@28221|Deltaproteobacteria,2M8XB@213115|Desulfovibrionales	28221|Deltaproteobacteria	D	Cell shape determining protein MreB Mrl	-	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
k59_72019_1	880072.Desac_2426	1.65e-32	115.0	2E79S@1|root,331TB@2|Bacteria,1NABI@1224|Proteobacteria,42V7R@68525|delta/epsilon subdivisions,2WRM1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_109863_1	1249627.D779_0358	5.38e-46	157.0	COG3676@1|root,COG3677@1|root,COG3676@2|Bacteria,COG3677@2|Bacteria,1R7ZF@1224|Proteobacteria,1S6YQ@1236|Gammaproteobacteria,1WYGX@135613|Chromatiales	135613|Chromatiales	L	ISXO2-like transposase domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS1595,Zn_Tnp_IS1595
k59_238571_1	1089550.ATTH01000001_gene407	2.15e-48	175.0	COG0466@1|root,COG0466@2|Bacteria,4NE1G@976|Bacteroidetes,1FJX3@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	O	Found in ATP-dependent protease La (LON)	lon	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
k59_34179_1	1121405.dsmv_1970	7.53e-43	142.0	COG2329@1|root,COG2329@2|Bacteria,1NBCH@1224|Proteobacteria,42VX2@68525|delta/epsilon subdivisions,2WRPB@28221|Deltaproteobacteria,2MM0B@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	ABM
k59_186127_1	1382306.JNIM01000001_gene2574	4.65e-45	162.0	COG1253@1|root,COG1253@2|Bacteria,2G6D1@200795|Chloroflexi	200795|Chloroflexi	S	CBS domain containing protein	-	-	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	CBS,CorC_HlyC,DUF21
k59_162784_1	1232437.KL662010_gene1571	6.95e-112	330.0	COG2357@1|root,COG2357@2|Bacteria,1RCHE@1224|Proteobacteria,42PPK@68525|delta/epsilon subdivisions,2WJBS@28221|Deltaproteobacteria,2MHSG@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Region found in RelA / SpoT proteins	-	-	-	-	-	-	-	-	-	-	-	-	RelA_SpoT
k59_34182_1	1121459.AQXE01000006_gene272	2.57e-53	191.0	COG0013@1|root,COG0013@2|Bacteria,1MU9A@1224|Proteobacteria,42M70@68525|delta/epsilon subdivisions,2WJA8@28221|Deltaproteobacteria,2M7ZN@213115|Desulfovibrionales	28221|Deltaproteobacteria	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
k59_11600_1	648757.Rvan_1012	1.51e-05	54.3	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,2TQPZ@28211|Alphaproteobacteria,3N61M@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	M	Belongs to the peptidase S1C family	degP	GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ,PDZ_2,Trypsin_2
k59_117047_2	879212.DespoDRAFT_01456	2.41e-62	193.0	COG0614@1|root,COG0614@2|Bacteria,1N7EM@1224|Proteobacteria,42VJU@68525|delta/epsilon subdivisions,2WRA4@28221|Deltaproteobacteria,2MM3T@213118|Desulfobacterales	28221|Deltaproteobacteria	P	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_3
k59_72027_1	439235.Dalk_0153	3.81e-110	333.0	COG0786@1|root,COG0786@2|Bacteria,1RKK8@1224|Proteobacteria,43BET@68525|delta/epsilon subdivisions,2X6T9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Sodium/glutamate symporter	-	-	-	ko:K03312	-	-	-	-	ko00000,ko02000	2.A.27	-	-	Glt_symporter
k59_238574_1	269799.Gmet_0865	3.44e-41	144.0	COG0283@1|root,COG0283@2|Bacteria,1MUUD@1224|Proteobacteria,42S4S@68525|delta/epsilon subdivisions,2WNIV@28221|Deltaproteobacteria,43S1H@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	cytidylate kinase activity	cmk	GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin
k59_186137_1	1192034.CAP_4385	1.5e-38	146.0	COG0427@1|root,COG1670@1|root,COG0427@2|Bacteria,COG1670@2|Bacteria,1MUGE@1224|Proteobacteria,42MHC@68525|delta/epsilon subdivisions,2WINZ@28221|Deltaproteobacteria,2YW0C@29|Myxococcales	28221|Deltaproteobacteria	C	Acetyl-CoA hydrolase/transferase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AcetylCoA_hyd_C,AcetylCoA_hydro,Acetyltransf_1
k59_150741_1	596152.DesU5LDRAFT_1613	1.45e-51	176.0	COG3547@1|root,COG3547@2|Bacteria,1NGR7@1224|Proteobacteria,42NNQ@68525|delta/epsilon subdivisions,2WM2H@28221|Deltaproteobacteria,2MGDQ@213115|Desulfovibrionales	28221|Deltaproteobacteria	L	PFAM transposase IS116 IS110 IS902 family	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_90730_3	28229.ND2E_3048	0.000115	45.4	2DDKV@1|root,32U1R@2|Bacteria,1N5SP@1224|Proteobacteria,1SAQN@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M15_3
k59_113644_1	1121403.AUCV01000014_gene4647	1.43e-49	174.0	COG0318@1|root,COG0318@2|Bacteria,1MXPB@1224|Proteobacteria,42QVY@68525|delta/epsilon subdivisions,2WTEZ@28221|Deltaproteobacteria,2MN2I@213118|Desulfobacterales	28221|Deltaproteobacteria	IQ	AMP-binding enzyme	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
k59_219244_1	1123371.ATXH01000010_gene735	1.45e-108	324.0	COG0538@1|root,COG0538@2|Bacteria,2GH2J@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	C	Isocitrate/isopropylmalate dehydrogenase	-	-	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
k59_165919_1	1327935.A0A060AN20_9CAUD	7.31e-21	102.0	4QB40@10239|Viruses,4QV3M@35237|dsDNA viruses  no RNA stage,4QPWY@28883|Caudovirales,4QHVQ@10662|Myoviridae	10662|Myoviridae	S	nucleotide binding	-	GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009058,GO:0009059,GO:0009987,GO:0016032,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019058,GO:0019079,GO:0019438,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0039686,GO:0039693,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044403,GO:0044419,GO:0046483,GO:0051704,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576	-	-	-	-	-	-	-	-	-	-	-
k59_37750_1	1232437.KL662020_gene648	3.25e-14	67.0	COG1908@1|root,COG1908@2|Bacteria,1NGSG@1224|Proteobacteria,42XN0@68525|delta/epsilon subdivisions,2WTGE@28221|Deltaproteobacteria,2MM9B@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Methyl-viologen-reducing hydrogenase, delta subunit	-	-	-	-	-	-	-	-	-	-	-	-	FlpD
k59_37750_2	1121472.AQWN01000006_gene1835	1e-35	132.0	COG1035@1|root,COG1143@1|root,COG1035@2|Bacteria,COG1143@2|Bacteria,1TPBM@1239|Firmicutes,24CJH@186801|Clostridia,260PH@186807|Peptococcaceae	186801|Clostridia	C	PFAM Coenzyme F420 hydrogenase dehydrogenase beta subunit	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_17,Fer4_8,FrhB_FdhB_C
k59_219248_1	1121468.AUBR01000012_gene2604	1.54e-15	71.6	2F79F@1|root,33ZQP@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_219248_3	880072.Desac_0497	5.84e-41	135.0	2FJKA@1|root,34B9P@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_165928_1	1322246.BN4_20128	8.02e-44	157.0	COG0845@1|root,COG0845@2|Bacteria,1PEVY@1224|Proteobacteria,42NTH@68525|delta/epsilon subdivisions,2WJ8N@28221|Deltaproteobacteria,2M9JT@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_3,HlyD_D23
k59_29391_1	96561.Dole_1776	4.65e-52	186.0	COG4191@1|root,COG4191@2|Bacteria,1R9AK@1224|Proteobacteria,42Q2G@68525|delta/epsilon subdivisions,2WM8Y@28221|Deltaproteobacteria,2MI84@213118|Desulfobacterales	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
k59_158897_1	65393.PCC7424_3781	8.8e-36	130.0	COG4803@1|root,COG4803@2|Bacteria,1G531@1117|Cyanobacteria,3KHQE@43988|Cyanothece	1117|Cyanobacteria	S	PFAM membrane protein of uknown function UCP014873	-	-	-	-	-	-	-	-	-	-	-	-	DUF1269
k59_128739_1	1167006.UWK_00197	2.31e-37	143.0	COG0834@1|root,COG2204@1|root,COG5002@1|root,COG0834@2|Bacteria,COG2204@2|Bacteria,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,43CS7@68525|delta/epsilon subdivisions,2X7ZW@28221|Deltaproteobacteria,2MPMK@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_7,PAS_8,PAS_9,Response_reg,SBP_bac_3,sCache_3_2
k59_113670_1	1151292.QEW_1559	3.22e-36	134.0	COG0331@1|root,COG0331@2|Bacteria,1TPB7@1239|Firmicutes,247UF@186801|Clostridia,25RFG@186804|Peptostreptococcaceae	186801|Clostridia	I	malonyl CoA-acyl carrier protein transacylase	fabD	-	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
k59_241862_1	1121405.dsmv_2318	1.29e-92	296.0	COG0421@1|root,COG0421@2|Bacteria,1P220@1224|Proteobacteria,42NG6@68525|delta/epsilon subdivisions,2WIRU@28221|Deltaproteobacteria,2MK6C@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	-	-	-	-	-	-	-	-	-	-	-	-	Spermine_synth
k59_106112_1	985867.AEWF01000002_gene1646	8.8e-19	88.2	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2TQPG@28211|Alphaproteobacteria,47F3B@766|Rickettsiales	766|Rickettsiales	T	Sigma-54 interaction domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
k59_22042_2	1123371.ATXH01000028_gene20	5.33e-40	137.0	COG2018@1|root,COG2018@2|Bacteria,2GIJ4@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	S	Roadblock/LC7 domain	-	-	-	-	-	-	-	-	-	-	-	-	Robl_LC7
k59_150773_1	1120953.AUBH01000004_gene3047	6.87e-05	50.4	COG0639@1|root,COG0639@2|Bacteria,1QEIM@1224|Proteobacteria,1RZDP@1236|Gammaproteobacteria,46BP8@72275|Alteromonadaceae	1236|Gammaproteobacteria	T	Protein phosphatase 2A homologues, catalytic domain.	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
k59_144029_1	1123261.AXDW01000010_gene341	2.65e-36	142.0	COG3497@1|root,COG3497@2|Bacteria,1NSAQ@1224|Proteobacteria,1SKZH@1236|Gammaproteobacteria,1X9AM@135614|Xanthomonadales	135614|Xanthomonadales	S	Phage tail sheath protein subtilisin-like domain	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_219266_1	1121456.ATVA01000011_gene1345	4.6e-69	229.0	COG2204@1|root,COG4191@1|root,COG2204@2|Bacteria,COG4191@2|Bacteria,1QZPK@1224|Proteobacteria,42NQE@68525|delta/epsilon subdivisions,2WJPH@28221|Deltaproteobacteria,2M8MZ@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,PAS_4,PAS_9,Response_reg
k59_90769_1	448385.sce8911	3.99e-72	229.0	COG0520@1|root,COG0520@2|Bacteria,1MUPD@1224|Proteobacteria,42PJT@68525|delta/epsilon subdivisions,2WKPW@28221|Deltaproteobacteria,2YXCR@29|Myxococcales	28221|Deltaproteobacteria	E	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
k59_67509_1	1298867.AUES01000051_gene4507	7.6e-70	231.0	COG0845@1|root,COG0845@2|Bacteria,1N97Q@1224|Proteobacteria,2U22Z@28211|Alphaproteobacteria,3K3DU@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	M	Barrel-sandwich domain of CusB or HlyD membrane-fusion	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,GAF,HlyD_3,HlyD_D23
k59_6272_1	439235.Dalk_2930	1.43e-60	203.0	COG2203@1|root,COG2204@1|root,COG2206@1|root,COG2203@2|Bacteria,COG2204@2|Bacteria,COG2206@2|Bacteria,1RAQS@1224|Proteobacteria,42MEJ@68525|delta/epsilon subdivisions,2X71A@28221|Deltaproteobacteria,2MHS0@213118|Desulfobacterales	28221|Deltaproteobacteria	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GAF_3,GGDEF,HD,Response_reg
k59_61009_1	933262.AXAM01000039_gene1154	8.37e-10	55.8	2EINH@1|root,33CDW@2|Bacteria,1NN5W@1224|Proteobacteria,42XC5@68525|delta/epsilon subdivisions,2WT26@28221|Deltaproteobacteria,2MMA6@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_307_2	698761.RTCIAT899_CH14690	6.94e-17	79.0	COG0457@1|root,COG0457@2|Bacteria,1N6TJ@1224|Proteobacteria,2UG5W@28211|Alphaproteobacteria,4BEWQ@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_12,TPR_16,TPR_19,TPR_2
k59_144357_1	1232410.KI421426_gene1498	5.07e-24	99.0	COG3713@1|root,COG3713@2|Bacteria,1N0BC@1224|Proteobacteria,437BN@68525|delta/epsilon subdivisions,2X2GT@28221|Deltaproteobacteria,43VCY@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	MltA-interacting protein MipA	-	-	-	-	-	-	-	-	-	-	-	-	MipA
k59_144357_2	439235.Dalk_2921	2.93e-38	133.0	COG2172@1|root,COG2172@2|Bacteria,1N9RD@1224|Proteobacteria,42TUP@68525|delta/epsilon subdivisions,2WQJB@28221|Deltaproteobacteria,2MKT2@213118|Desulfobacterales	28221|Deltaproteobacteria	T	anti-sigma regulatory factor	-	-	2.7.11.1	ko:K04757	-	-	-	-	ko00000,ko01000,ko01001,ko03021	-	-	-	HATPase_c_2
k59_227728_1	5827.XP_004225007.1	1.48e-09	65.5	COG0664@1|root,KOG1113@2759|Eukaryota,3Y9W7@5794|Apicomplexa,3KAI4@422676|Aconoidasida,3YWQ0@5819|Haemosporida	422676|Aconoidasida	T	cAMP-dependent protein kinase	-	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005952,GO:0019899,GO:0019900,GO:0019901,GO:0032991,GO:0034236,GO:0042802,GO:0044424,GO:0044464,GO:0051018	-	ko:K04739	ko04910,map04910	-	-	-	ko00000,ko00001	-	-	-	cNMP_binding
k59_7949_1	335543.Sfum_0459	5.43e-21	86.3	COG0314@1|root,COG0314@2|Bacteria,1N0DM@1224|Proteobacteria,42U56@68525|delta/epsilon subdivisions,2WQRU@28221|Deltaproteobacteria,2MQM0@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	MoaE protein	-	-	2.8.1.12	ko:K03635	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09395	RC02507	ko00000,ko00001,ko01000	-	-	-	MoaE
k59_7949_2	561175.KB894093_gene2751	0.000624	44.3	COG4221@1|root,COG4221@2|Bacteria,2HA4H@201174|Actinobacteria	201174|Actinobacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
k59_91249_1	1254432.SCE1572_37530	2.66e-46	163.0	COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,42NES@68525|delta/epsilon subdivisions,2WJ0V@28221|Deltaproteobacteria,2YU38@29|Myxococcales	28221|Deltaproteobacteria	NU	Type II secretion system (T2SS), protein F	pilC	-	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
k59_7952_1	7668.SPU_003061-tr	1.78e-71	243.0	COG2801@1|root,KOG0017@2759|Eukaryota,38F42@33154|Opisthokonta,3BA5H@33208|Metazoa,3CWAK@33213|Bilateria	33208|Metazoa	E	K02A2.6-like	-	-	-	-	-	-	-	-	-	-	-	-	RVT_1,SCAN,gag-asp_proteas,rve,zf-CCHC,zf-H2C2
k59_91250_1	1247726.MIM_c01150	2.34e-14	77.0	COG0559@1|root,COG0559@2|Bacteria,1N5XH@1224|Proteobacteria,2VHAJ@28216|Betaproteobacteria,3T8QY@506|Alcaligenaceae	28216|Betaproteobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
k59_212552_1	439235.Dalk_0092	1.12e-68	236.0	COG1413@1|root,COG2199@1|root,COG3899@1|root,COG1413@2|Bacteria,COG2199@2|Bacteria,COG3899@2|Bacteria	2|Bacteria	T	PFAM Protein kinase domain	cpeY	-	2.7.11.1,2.7.7.65	ko:K05385,ko:K12132,ko:K13590	ko00196,ko01100,ko04112,map00196,map01100,map04112	-	-	-	ko00000,ko00001,ko00194,ko01000,ko01001	-	-	-	AAA_16,EAL,GGDEF,Trans_reg_C
k59_76124_1	1265505.ATUG01000003_gene347	2.67e-180	525.0	COG0243@1|root,COG3383@1|root,COG0243@2|Bacteria,COG3383@2|Bacteria,1MW3N@1224|Proteobacteria,43BJY@68525|delta/epsilon subdivisions,2WIWD@28221|Deltaproteobacteria,2MIG4@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	fdnG-2	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding,TAT_signal
k59_15443_1	1265505.ATUG01000003_gene713	6.49e-31	120.0	COG2414@1|root,COG2414@2|Bacteria,1MWBB@1224|Proteobacteria,42NR7@68525|delta/epsilon subdivisions,2WK49@28221|Deltaproteobacteria,2MHYC@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Aldehyde ferredoxin oxidoreductase	-	-	1.2.7.5	ko:K03738	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00309	R08571	RC00242	ko00000,ko00001,ko00002,ko01000	-	-	-	AFOR_C,AFOR_N
k59_15443_2	933262.AXAM01000006_gene1865	2.01e-22	99.0	COG3064@1|root,COG3064@2|Bacteria,1N60E@1224|Proteobacteria,42W12@68525|delta/epsilon subdivisions,2WRI0@28221|Deltaproteobacteria,2MKYV@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	DnaJ
k59_129255_1	472759.Nhal_0237	9.1e-54	184.0	COG3385@1|root,COG3385@2|Bacteria,1PMXF@1224|Proteobacteria,1RMHK@1236|Gammaproteobacteria,1X1NE@135613|Chromatiales	135613|Chromatiales	L	transposase IS4	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DUF4372
k59_98897_1	1499967.BAYZ01000180_gene4413	5.06e-70	224.0	28IMC@1|root,2Z8MV@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_83685_1	1173263.Syn7502_02036	5.32e-25	101.0	COG0113@1|root,COG0113@2|Bacteria,1G0YH@1117|Cyanobacteria,1GYDI@1129|Synechococcus	1117|Cyanobacteria	H	Belongs to the ALAD family	hemB	-	4.2.1.24	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00036	RC00918,RC01781	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ALAD
k59_167067_1	706587.Desti_1176	4.31e-69	221.0	COG0468@1|root,COG0468@2|Bacteria,1MU3C@1224|Proteobacteria,42M69@68525|delta/epsilon subdivisions,2WIYC@28221|Deltaproteobacteria,2MQ3R@213462|Syntrophobacterales	28221|Deltaproteobacteria	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
k59_197456_1	1121405.dsmv_1058	4.87e-47	160.0	COG1180@1|root,COG1180@2|Bacteria,1NQC1@1224|Proteobacteria,42N7U@68525|delta/epsilon subdivisions,2WJ81@28221|Deltaproteobacteria,2MI27@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM Radical SAM	-	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
k59_68632_1	1304885.AUEY01000051_gene1500	6.17e-15	75.5	COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,42NCR@68525|delta/epsilon subdivisions,2WKMY@28221|Deltaproteobacteria,2MHTZ@213118|Desulfobacterales	28221|Deltaproteobacteria	V	ABC transporter transmembrane region	-	-	-	ko:K06147,ko:K18889	ko02010,map02010	M00707	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.106,3.A.1.106.13,3.A.1.106.5,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
k59_68632_2	177437.HRM2_33040	1.9e-19	88.6	COG0557@1|root,COG0557@2|Bacteria,1MUS6@1224|Proteobacteria,42NHP@68525|delta/epsilon subdivisions,2X6U1@28221|Deltaproteobacteria,2MHMI@213118|Desulfobacterales	28221|Deltaproteobacteria	K	PFAM ribonuclease II	-	-	3.1.13.1	ko:K01147,ko:K12573	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	OB_RNB,RNB,S1
k59_106510_1	1353528.DT23_03550	1.85e-06	50.8	COG3267@1|root,COG3267@2|Bacteria,1MU3G@1224|Proteobacteria,2U1EJ@28211|Alphaproteobacteria,2XMYW@285107|Thioclava	28211|Alphaproteobacteria	U	AAA domain	exeA	-	-	ko:K02450	-	M00331	-	-	ko00000,ko00002,ko02044	9.B.42	-	-	AAA_22
k59_106510_2	177437.HRM2_p00160	4.81e-19	84.0	COG0358@1|root,COG0358@2|Bacteria	2|Bacteria	L	DNA primase activity	-	-	-	-	-	-	-	-	-	-	-	-	PriCT_2,Prim-Pol,Toprim_2,Toprim_3,zf-CHC2
k59_159589_1	1121405.dsmv_2542	1.69e-115	346.0	COG0007@1|root,COG1587@1|root,COG0007@2|Bacteria,COG1587@2|Bacteria,1MUI0@1224|Proteobacteria,42MCB@68525|delta/epsilon subdivisions,2WIRJ@28221|Deltaproteobacteria,2MISA@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Belongs to the precorrin methyltransferase family	hemD	-	1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.4	ko:K02302,ko:K02303,ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03165,R03194,R03947	RC00003,RC00871,RC01012,RC01034,RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4,TP_methylase
k59_332_1	1121405.dsmv_0959	1.6e-40	147.0	COG1530@1|root,COG1530@2|Bacteria,1MV65@1224|Proteobacteria,42M5E@68525|delta/epsilon subdivisions,2WIV6@28221|Deltaproteobacteria,2MIDU@213118|Desulfobacterales	28221|Deltaproteobacteria	J	TIGRFAM ribonuclease, Rne Rng family	rne	-	3.1.26.12	ko:K08300,ko:K08301	ko03018,map03018	M00394	-	-	ko00000,ko00001,ko00002,ko01000,ko03009,ko03019	-	-	-	RNase_E_G,S1
k59_151976_2	768670.Calni_1591	7.93e-08	56.6	COG0711@1|root,COG0711@2|Bacteria,2GFUF@200930|Deferribacteres	200930|Deferribacteres	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	-	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
k59_61057_1	903818.KI912268_gene2642	2.27e-26	112.0	COG3519@1|root,COG3519@2|Bacteria,3Y34T@57723|Acidobacteria	57723|Acidobacteria	S	Type VI secretion system, TssF	-	-	-	ko:K11896	-	M00334	-	-	ko00000,ko00002,ko02044	3.A.23.1	-	-	T6SS_TssF
k59_83692_1	1355374.JARU01000001_gene461	2.15e-69	222.0	COG1638@1|root,COG1638@2|Bacteria,1MVHC@1224|Proteobacteria,42M9R@68525|delta/epsilon subdivisions,2YM9K@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	transporter solute receptor, DctP family	-	-	-	ko:K11688	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.56.1	-	-	DctP
k59_144383_1	1565314.OA34_12940	1.82e-85	263.0	COG3328@1|root,COG3328@2|Bacteria,1MU4P@1224|Proteobacteria,4300T@68525|delta/epsilon subdivisions,2YRU4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_mut
k59_197464_1	1167006.UWK_00417	3.12e-64	205.0	COG0705@1|root,COG0705@2|Bacteria,1PRTP@1224|Proteobacteria,42M6N@68525|delta/epsilon subdivisions,2WJW4@28221|Deltaproteobacteria,2MJR6@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Rhomboid family	-	-	3.4.21.105	ko:K19225	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Rhomboid
k59_235392_1	357804.Ping_1883	1.34e-90	286.0	COG0586@1|root,COG0671@1|root,COG0586@2|Bacteria,COG0671@2|Bacteria,1MX4M@1224|Proteobacteria,1RPB1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	Pfam SNARE associated Golgi protein	-	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	SNARE_assoc
k59_197465_1	1123504.JQKD01000002_gene3952	8.9e-21	89.4	COG0411@1|root,COG0411@2|Bacteria,1MUTY@1224|Proteobacteria,2WF9J@28216|Betaproteobacteria	28216|Betaproteobacteria	E	Branched-chain amino acid ATP-binding cassette transporter	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
k59_23097_1	335543.Sfum_2864	2.83e-81	249.0	COG2518@1|root,COG2518@2|Bacteria,1MXQC@1224|Proteobacteria,42QXM@68525|delta/epsilon subdivisions,2WMZI@28221|Deltaproteobacteria,2MRM3@213462|Syntrophobacterales	28221|Deltaproteobacteria	O	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	pcm	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
k59_189861_1	439481.Aboo_0820	2.44e-55	192.0	COG0187@1|root,arCOG04371@2157|Archaea,2XSVX@28890|Euryarchaeota,3F2HP@33867|unclassified Euryarchaeota	28890|Euryarchaeota	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
k59_30678_1	646529.Desaci_0555	1.03e-09	63.2	COG0745@1|root,COG0745@2|Bacteria,1U3FH@1239|Firmicutes,248BR@186801|Clostridia,263PS@186807|Peptococcaceae	186801|Clostridia	K	PFAM Response regulator receiver domain	-	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
k59_354_7	591157.SSLG_00500	4.14e-38	137.0	2BGX2@1|root,32AX0@2|Bacteria,2IIA3@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_121683_1	1499967.BAYZ01000123_gene2540	1.74e-51	177.0	COG0064@1|root,COG0064@2|Bacteria,2NNPK@2323|unclassified Bacteria	2|Bacteria	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564	6.1.1.12,6.3.5.6,6.3.5.7	ko:K01876,ko:K02434	ko00970,ko01100,map00970,map01100	M00359,M00360	R03905,R04212,R05577	RC00010,RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GatB_N,GatB_Yqey
k59_224699_2	1133850.SHJG_8502	1.97e-27	115.0	COG0243@1|root,COG0243@2|Bacteria,2GNYQ@201174|Actinobacteria	201174|Actinobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_6,Fer2,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NAD_binding_1
k59_164059_1	985053.VMUT_1177	4.12e-58	195.0	COG0160@1|root,arCOG00916@2157|Archaea,2XPMV@28889|Crenarchaeota	28889|Crenarchaeota	E	Aminotransferase class-III	-	-	2.6.1.55	ko:K15372	ko00410,ko00430,ko01100,map00410,map00430,map01100	-	R00908,R01684	RC00006,RC00062	ko00000,ko00001,ko01000	-	-	-	Aminotran_3
k59_187605_1	1121405.dsmv_0552	3.66e-07	51.6	COG3303@1|root,COG3303@2|Bacteria,1P8CP@1224|Proteobacteria,42MXS@68525|delta/epsilon subdivisions,2WKEK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Seven times multi-haem cytochrome CxxCH	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554,Multi-haem_cyto
k59_187605_2	329726.AM1_0697	7.2e-37	138.0	COG0415@1|root,COG0415@2|Bacteria	2|Bacteria	L	Belongs to the DNA photolyase family	phr	-	4.1.99.3	ko:K01669	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_photolyase,FAD_binding_7
k59_73510_1	1121405.dsmv_2161	1.91e-96	296.0	COG0459@1|root,COG0459@2|Bacteria,1MURR@1224|Proteobacteria,42M52@68525|delta/epsilon subdivisions,2WIRK@28221|Deltaproteobacteria,2MHPV@213118|Desulfobacterales	28221|Deltaproteobacteria	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	-	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
k59_148608_1	177437.HRM2_26190	2.13e-60	194.0	COG0491@1|root,COG0491@2|Bacteria,1Q2C2@1224|Proteobacteria,42RVX@68525|delta/epsilon subdivisions,2WNQR@28221|Deltaproteobacteria,2MK0Q@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
k59_35738_1	439235.Dalk_3856	7.98e-93	281.0	COG0535@1|root,COG0535@2|Bacteria,1MUQP@1224|Proteobacteria,42M55@68525|delta/epsilon subdivisions,2WIKM@28221|Deltaproteobacteria,2MJ60@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM Radical SAM domain protein	-	-	-	ko:K22227	-	-	-	-	ko00000	-	-	-	Fer4_12,Fer4_14,Radical_SAM,SPASM
k59_42559_2	525318.HMPREF0497_2032	8.46e-05	46.6	COG2265@1|root,COG2265@2|Bacteria,1TP4H@1239|Firmicutes,4HA6M@91061|Bacilli,3F41R@33958|Lactobacillaceae	91061|Bacilli	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	rumA_2	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TRAM,tRNA_U5-meth_tr
k59_179071_1	1448857.JFAP01000008_gene605	1.36e-17	84.3	COG2369@1|root,COG2369@2|Bacteria,1R40R@1224|Proteobacteria,42P0H@68525|delta/epsilon subdivisions,2YNDE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Phage Mu protein F like protein	-	-	-	-	-	-	-	-	-	-	-	-	Phage_Mu_F
k59_233028_1	555779.Dthio_PD1963	8.59e-41	147.0	COG2509@1|root,COG2509@2|Bacteria,1MV6P@1224|Proteobacteria,42N2K@68525|delta/epsilon subdivisions,2WJ5D@28221|Deltaproteobacteria,2M8TA@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	FAD dependent oxidoreductase	-	-	-	ko:K07137	-	-	-	-	ko00000	-	-	-	DAO,FAD_binding_2,GIDA,HI0933_like,Pyr_redox_2
k59_233028_2	1232437.KL661988_gene85	2.58e-60	189.0	COG0655@1|root,COG0655@2|Bacteria,1QV9P@1224|Proteobacteria,42RJT@68525|delta/epsilon subdivisions,2WNM5@28221|Deltaproteobacteria,2MJWR@213118|Desulfobacterales	28221|Deltaproteobacteria	S	NADPH-dependent FMN reductase	-	-	1.6.5.2	ko:K03809	ko00130,ko01110,map00130,map01110	-	R02964,R03643,R03816	RC00819	ko00000,ko00001,ko01000	-	-	-	FMN_red
k59_156963_1	96561.Dole_2640	1.61e-38	129.0	COG5304@1|root,COG5304@2|Bacteria,1N9U3@1224|Proteobacteria,4320A@68525|delta/epsilon subdivisions,2WWJS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_156963_2	1121405.dsmv_3344	3.65e-54	170.0	COG2929@1|root,COG2929@2|Bacteria,1N3AZ@1224|Proteobacteria,438DV@68525|delta/epsilon subdivisions,2WXRG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Ribonuclease toxin, BrnT, of type II toxin-antitoxin system	-	-	-	ko:K09803	-	-	-	-	ko00000	-	-	-	BrnT_toxin
k59_111394_1	335543.Sfum_1549	3.79e-92	301.0	COG0085@1|root,COG0085@2|Bacteria,1MUC4@1224|Proteobacteria,43DMZ@68525|delta/epsilon subdivisions,2WIW5@28221|Deltaproteobacteria,2MR0B@213462|Syntrophobacterales	28221|Deltaproteobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
k59_103900_1	192952.MM_0673	5.73e-87	270.0	COG1363@1|root,arCOG01518@2157|Archaea,2XT3M@28890|Euryarchaeota,2N94F@224756|Methanomicrobia	224756|Methanomicrobia	G	peptidase M42 family protein	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M42
k59_210103_1	335543.Sfum_2334	3.79e-05	47.4	COG5000@1|root,COG5000@2|Bacteria	2|Bacteria	T	phosphorelay sensor kinase activity	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,PAS,PAS_4,PAS_9,dCache_1
k59_210103_2	335543.Sfum_3924	1.86e-50	170.0	COG0730@1|root,COG0730@2|Bacteria,1R99G@1224|Proteobacteria,42NBX@68525|delta/epsilon subdivisions,2WMF4@28221|Deltaproteobacteria,2MRYU@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Sulfite exporter TauE/SafE	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
k59_118361_1	335543.Sfum_0679	1.11e-182	540.0	COG0617@1|root,COG0618@1|root,COG3620@1|root,COG0617@2|Bacteria,COG0618@2|Bacteria,COG3620@2|Bacteria,1MU2X@1224|Proteobacteria,42MJJ@68525|delta/epsilon subdivisions,2WJBN@28221|Deltaproteobacteria,2MQAY@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	tRNA nucleotidyltransferase poly(A) polymerase	ccaA	-	2.7.7.72	ko:K00974	ko03013,map03013	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016	-	-	-	CBS,DHH,DHHA1,PolyA_pol,PolyA_pol_RNAbd
k59_96209_1	1163730.FFONT_0734	3.23e-12	69.7	COG1042@1|root,arCOG01340@2157|Archaea,2XPR9@28889|Crenarchaeota	28889|Crenarchaeota	C	PFAM CoA-binding domain protein	-	-	6.2.1.13	ko:K01905	ko00010,ko00620,ko00640,ko01100,ko01120,map00010,map00620,map00640,map01100,map01120	-	R00229,R00920	RC00004,RC00012,RC00014	ko00000,ko00001,ko01000,ko01004	-	-	-	CoA_binding_2,Succ_CoA_lig
k59_81143_1	933262.AXAM01000044_gene1408	2.25e-100	308.0	COG3385@1|root,COG3385@2|Bacteria,1MVRM@1224|Proteobacteria,42U5W@68525|delta/epsilon subdivisions,2WQUQ@28221|Deltaproteobacteria,2MKFC@213118|Desulfobacterales	28221|Deltaproteobacteria	L	PFAM transposase IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,Nterm_IS4
k59_65425_1	880072.Desac_0014	3.36e-80	256.0	COG1219@1|root,COG1219@2|Bacteria,1MWIZ@1224|Proteobacteria,42N1Z@68525|delta/epsilon subdivisions,2WJUS@28221|Deltaproteobacteria,2MR6M@213462|Syntrophobacterales	28221|Deltaproteobacteria	O	Belongs to the ClpX chaperone family	-	-	-	-	-	-	-	-	-	-	-	-	AAA_2,ClpB_D2-small
k59_27348_2	383372.Rcas_3628	1.16e-07	53.9	COG0399@1|root,COG0399@2|Bacteria,2G7WW@200795|Chloroflexi,37751@32061|Chloroflexia	32061|Chloroflexia	E	aromatic amino acid beta-eliminating lyase threonine aldolase	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
k59_224706_2	335543.Sfum_0755	1.56e-42	163.0	COG0823@1|root,COG0823@2|Bacteria,1MV09@1224|Proteobacteria,42PHP@68525|delta/epsilon subdivisions,2WIXN@28221|Deltaproteobacteria,2MQDX@213462|Syntrophobacterales	28221|Deltaproteobacteria	U	Involved in the TonB-independent uptake of proteins	tolB	GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0019534,GO:0022857,GO:0051179,GO:0051234,GO:0055085,GO:1901998	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40,TolB_N
k59_81148_1	1121405.dsmv_0557	4.71e-36	136.0	COG0427@1|root,COG0454@1|root,COG0427@2|Bacteria,COG0456@2|Bacteria,1MUGE@1224|Proteobacteria,42MHC@68525|delta/epsilon subdivisions,2WINZ@28221|Deltaproteobacteria,2MJ4K@213118|Desulfobacterales	28221|Deltaproteobacteria	CK	PFAM Acetyl-CoA hydrolase transferase	-	-	-	-	-	-	-	-	-	-	-	-	AcetylCoA_hyd_C,AcetylCoA_hydro,Acetyltransf_1
k59_4312_1	330214.NIDE3866	2.84e-33	136.0	COG0045@1|root,COG1042@1|root,COG1670@1|root,COG0045@2|Bacteria,COG1042@2|Bacteria,COG1670@2|Bacteria,3J0ZI@40117|Nitrospirae	40117|Nitrospirae	C	ATP-grasp domain	-	-	6.2.1.13	ko:K01905,ko:K22224	ko00010,ko00620,ko00640,ko01100,ko01120,map00010,map00620,map00640,map01100,map01120	-	R00229,R00920	RC00004,RC00012,RC00014	ko00000,ko00001,ko01000,ko01004	-	-	-	ATP-grasp_5,CoA_binding_2,Succ_CoA_lig
k59_134346_1	701176.VIBRN418_16028	4.18e-42	155.0	COG1574@1|root,COG1574@2|Bacteria,1MWP2@1224|Proteobacteria,1RNB7@1236|Gammaproteobacteria,1XTUF@135623|Vibrionales	135623|Vibrionales	S	metal-dependent hydrolase with the TIM-barrel fold	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
k59_88473_1	743722.Sph21_2433	1.02e-37	140.0	COG0463@1|root,COG0463@2|Bacteria,4PKUK@976|Bacteroidetes,1IS1H@117747|Sphingobacteriia	976|Bacteroidetes	M	N-terminal domain of galactosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_7C,Glycos_transf_2
k59_13143_1	96561.Dole_2447	1.34e-30	124.0	COG2199@1|root,COG3290@1|root,COG2199@2|Bacteria,COG3290@2|Bacteria,1R4NY@1224|Proteobacteria,43AEW@68525|delta/epsilon subdivisions,2WPD9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS_9
k59_126799_2	1232428.CAVO010000023_gene1712	1.41e-11	70.1	COG0209@1|root,COG0209@2|Bacteria,1TPFH@1239|Firmicutes,4H3X9@909932|Negativicutes	909932|Negativicutes	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	-	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_lgC,Ribonuc_red_lgN
k59_217301_1	933262.AXAM01000022_gene3226	5.01e-28	113.0	COG0008@1|root,COG0008@2|Bacteria,1MUCR@1224|Proteobacteria,42MAI@68525|delta/epsilon subdivisions,2WJ8M@28221|Deltaproteobacteria,2MHXE@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
k59_134353_1	1121405.dsmv_0965	1.88e-112	347.0	COG0550@1|root,COG0550@2|Bacteria,1MUFZ@1224|Proteobacteria,42MM9@68525|delta/epsilon subdivisions,2WJTT@28221|Deltaproteobacteria,2MITA@213118|Desulfobacterales	28221|Deltaproteobacteria	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,zf-C4_Topoisom
k59_88480_1	1265505.ATUG01000002_gene1818	7.92e-75	241.0	COG0664@1|root,COG0664@2|Bacteria,1R5Z0@1224|Proteobacteria,42Q0Q@68525|delta/epsilon subdivisions,2WKKJ@28221|Deltaproteobacteria,2MI6B@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Putative methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_20,cNMP_binding
k59_58625_1	644282.Deba_0066	1.26e-38	144.0	COG2203@1|root,COG4251@1|root,COG2203@2|Bacteria,COG4251@2|Bacteria,1RGKE@1224|Proteobacteria,43EF4@68525|delta/epsilon subdivisions,2X87I@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	SMART ATP-binding region ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
k59_239787_1	1206720.BAFQ01000011_gene323	2.94e-16	80.9	COG3119@1|root,COG3119@2|Bacteria,2I9IZ@201174|Actinobacteria,4G8Q1@85025|Nocardiaceae	201174|Actinobacteria	P	Sulfatase	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
k59_141874_1	419665.Maeo_1141	7.09e-96	317.0	COG1933@1|root,arCOG03147@2157|Archaea,arCOG04447@2157|Archaea,2XU5S@28890|Euryarchaeota,23Q0E@183939|Methanococci	183939|Methanococci	L	Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase	polC	-	2.7.7.7	ko:K02322	ko00230,ko00240,ko01100,ko03030,map00230,map00240,map01100,map03030	M00264	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032	-	-	-	Intein_splicing,LAGLIDADG_3,PolC_DP2
k59_164090_1	944479.JQLX01000010_gene642	1.46e-36	139.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,42M51@68525|delta/epsilon subdivisions,2WIPP@28221|Deltaproteobacteria,2M6BJ@213113|Desulfurellales	28221|Deltaproteobacteria	NU	Type II secretion system protein E	pilB	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE,T2SSE_N,cNMP_binding
k59_210121_1	42256.RradSPS_3033	1.82e-73	236.0	COG0240@1|root,COG0240@2|Bacteria,2HYHZ@201174|Actinobacteria,4CQSG@84995|Rubrobacteria	84995|Rubrobacteria	C	NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus	-	-	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	-	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
k59_20068_1	177437.HRM2_32510	9.71e-44	158.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,42NY2@68525|delta/epsilon subdivisions,2WJKQ@28221|Deltaproteobacteria,2MMVD@213118|Desulfobacterales	28221|Deltaproteobacteria	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	DUF1566,Pkinase
k59_35800_1	439235.Dalk_4244	5.24e-05	44.3	COG2331@1|root,COG2331@2|Bacteria,1N6Q9@1224|Proteobacteria,42V24@68525|delta/epsilon subdivisions,2WR87@28221|Deltaproteobacteria,2MKWE@213118|Desulfobacterales	28221|Deltaproteobacteria	S	regulatory protein, FmdB family	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
k59_73533_1	879212.DespoDRAFT_00344	4.44e-105	314.0	COG0842@1|root,COG0842@2|Bacteria,1MW5R@1224|Proteobacteria,42P7V@68525|delta/epsilon subdivisions,2WJQA@28221|Deltaproteobacteria,2MJ2Q@213118|Desulfobacterales	28221|Deltaproteobacteria	V	ABC-2 family transporter protein	ybhS	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC2_membrane_3
k59_210128_1	1121405.dsmv_1736	7.57e-165	469.0	COG0492@1|root,COG0492@2|Bacteria,1MV15@1224|Proteobacteria,42MHR@68525|delta/epsilon subdivisions,2WIY8@28221|Deltaproteobacteria,2MMXX@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
k59_239800_1	1121405.dsmv_3682	1.58e-36	128.0	COG3385@1|root,COG3385@2|Bacteria	2|Bacteria	L	transposase activity	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
k59_73538_1	1121405.dsmv_2390	2.64e-115	337.0	COG3385@1|root,COG3385@2|Bacteria,1R8CS@1224|Proteobacteria,42P9F@68525|delta/epsilon subdivisions,2WKTA@28221|Deltaproteobacteria,2MJAY@213118|Desulfobacterales	28221|Deltaproteobacteria	L	PFAM transposase IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_5,DDE_Tnp_2
k59_50299_1	1121434.AULY01000006_gene283	1.6e-22	97.4	COG0457@1|root,COG0457@2|Bacteria,1MYZU@1224|Proteobacteria,42SNQ@68525|delta/epsilon subdivisions,2WPHI@28221|Deltaproteobacteria,2M842@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	PFAM Tetratricopeptide	-	-	-	-	-	-	-	-	-	-	-	-	OmpA,TPR_11,TPR_16,TPR_19,TPR_2,TPR_6,TPR_8
k59_81177_1	1173027.Mic7113_1726	2.58e-19	94.7	COG2203@1|root,COG3899@1|root,COG4585@1|root,COG2203@2|Bacteria,COG3899@2|Bacteria,COG4585@2|Bacteria,1G041@1117|Cyanobacteria,1H9N4@1150|Oscillatoriales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	2.7.13.3	ko:K02480	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	GAF,HATPase_c,HisKA_3,PAS_4,PAS_9
k59_202502_1	667014.Thein_1260	8.8e-71	233.0	COG1916@1|root,COG1916@2|Bacteria,2GGX4@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_58648_1	1229909.NSED_08780	6.98e-48	162.0	COG0604@1|root,arCOG01458@2157|Archaea,41SZ9@651137|Thaumarchaeota	651137|Thaumarchaeota	C	PFAM Alcohol dehydrogenase GroES-like domain	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
k59_118413_1	1121405.dsmv_1666	1.37e-35	138.0	COG0243@1|root,COG0437@1|root,COG0243@2|Bacteria,COG0437@2|Bacteria,1MU1B@1224|Proteobacteria,42NEG@68525|delta/epsilon subdivisions,2WKHA@28221|Deltaproteobacteria,2MMPS@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	actB	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_7,Molybdop_Fe4S4,Molybdopterin,Molydop_binding
k59_194226_1	1304885.AUEY01000032_gene2011	5.62e-163	465.0	COG0136@1|root,COG0136@2|Bacteria,1MUHG@1224|Proteobacteria,42MDM@68525|delta/epsilon subdivisions,2WJ5Y@28221|Deltaproteobacteria,2MI9R@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate	asd	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
k59_210144_1	574087.Acear_1932	3.43e-11	68.6	COG2199@1|root,COG3437@1|root,COG2199@2|Bacteria,COG3437@2|Bacteria,1TQ0S@1239|Firmicutes,24800@186801|Clostridia,3WBCN@53433|Halanaerobiales	186801|Clostridia	T	metal-dependent phosphohydrolase HD sub domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,HD,HD_5,PAS,PAS_3,PAS_9
k59_88507_1	1121405.dsmv_1591	2.38e-76	240.0	COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,1MU8P@1224|Proteobacteria,42N1C@68525|delta/epsilon subdivisions,2WIP5@28221|Deltaproteobacteria,2MIF1@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	ribBA	-	3.5.4.25,4.1.99.12	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	DHBP_synthase,GTP_cyclohydro2
k59_217332_1	706587.Desti_4999	1.64e-66	218.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,42PXA@68525|delta/epsilon subdivisions,2WM6E@28221|Deltaproteobacteria,2MRCU@213462|Syntrophobacterales	28221|Deltaproteobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
k59_210149_1	933262.AXAM01000087_gene3293	1.39e-20	82.4	COG1724@1|root,COG1724@2|Bacteria,1N81N@1224|Proteobacteria,432TX@68525|delta/epsilon subdivisions,2WXN1@28221|Deltaproteobacteria,2MP49@213118|Desulfobacterales	28221|Deltaproteobacteria	N	HicA toxin of bacterial toxin-antitoxin,	-	-	-	-	-	-	-	-	-	-	-	-	HicA_toxin
k59_210149_2	933262.AXAM01000087_gene3292	5.42e-66	202.0	COG1598@1|root,COG1598@2|Bacteria,1NFAZ@1224|Proteobacteria	1224|Proteobacteria	S	PFAM Uncharacterised protein family UPF0150	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_96247_1	177437.HRM2_21960	3.36e-55	195.0	COG1924@1|root,COG3580@1|root,COG3581@1|root,COG1924@2|Bacteria,COG3580@2|Bacteria,COG3581@2|Bacteria,1PKG6@1224|Proteobacteria,42MY4@68525|delta/epsilon subdivisions,2WJFI@28221|Deltaproteobacteria,2MIP0@213118|Desulfobacterales	28221|Deltaproteobacteria	I	BadF BadG BcrA BcrD	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG,DUF2229
k59_217337_1	404589.Anae109_1578	5.36e-25	95.1	2AG2N@1|root,31670@2|Bacteria,1NNB1@1224|Proteobacteria,437DW@68525|delta/epsilon subdivisions,2X2K1@28221|Deltaproteobacteria,2Z2S0@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_217337_2	425104.Ssed_2791	1.49e-14	75.1	COG4262@1|root,COG4262@2|Bacteria,1QUPY@1224|Proteobacteria,1RMJV@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	-	-	-	-	-	-	-	-	-	-	-	-	Spermine_synth
k59_20093_1	314260.PB2503_10269	0.000105	48.1	COG1629@1|root,COG4771@2|Bacteria,1MUC1@1224|Proteobacteria,2U45M@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	TonB-dependent Receptor Plug Domain	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
k59_118430_1	861299.J421_1394	7.24e-21	95.9	COG1228@1|root,COG1228@2|Bacteria	2|Bacteria	Q	imidazolonepropionase activity	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
k59_210159_1	880072.Desac_0326	6.94e-68	220.0	COG1180@1|root,COG1180@2|Bacteria,1QW1I@1224|Proteobacteria,43BRG@68525|delta/epsilon subdivisions,2X72A@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	PFAM Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
k59_224727_1	706587.Desti_0878	1.68e-80	248.0	COG1962@1|root,COG1962@2|Bacteria,1R7QQ@1224|Proteobacteria	1224|Proteobacteria	H	TIGRFAM N5-methyltetrahydromethanopterin coenzyme M methyltransferase subunit H	-	-	2.1.1.86	ko:K00584	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00357,M00567	R04347	RC00035,RC00113,RC02892	ko00000,ko00001,ko00002,ko01000	-	-	-	MtrH
k59_81201_1	1304885.AUEY01000012_gene1801	2.38e-10	62.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42Q64@68525|delta/epsilon subdivisions,2WKDM@28221|Deltaproteobacteria,2MHU1@213118|Desulfobacterales	28221|Deltaproteobacteria	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal
k59_65455_1	186497.PF0254	5.12e-22	92.4	COG1909@1|root,arCOG04076@2157|Archaea,2XXSG@28890|Euryarchaeota,2440N@183968|Thermococci	183968|Thermococci	S	Belongs to the UPF0218 family	-	-	-	ko:K09735	-	-	-	-	ko00000	-	-	-	DUF359
k59_20099_1	485917.Phep_0085	1.53e-35	138.0	COG2304@1|root,COG2304@2|Bacteria,4NHJ2@976|Bacteroidetes,1IRM1@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM TROVE domain	-	-	-	-	-	-	-	-	-	-	-	-	TROVE
k59_27382_1	1394176.AWUO01000002_gene1618	4.85e-11	68.6	COG3291@1|root,COG5184@1|root,COG3291@2|Bacteria,COG5184@2|Bacteria,2IDH9@201174|Actinobacteria,4D0CR@85004|Bifidobacteriales	201174|Actinobacteria	M	Listeria-Bacteroides repeat domain (List_Bact_rpt)	-	-	-	-	-	-	-	-	-	-	-	-	Flg_new,RCC1,RCC1_2
k59_239823_1	1121405.dsmv_3781	4.95e-72	228.0	COG5421@1|root,COG5421@2|Bacteria,1R3NX@1224|Proteobacteria,42QDV@68525|delta/epsilon subdivisions,2WIRQ@28221|Deltaproteobacteria,2MN1S@213118|Desulfobacterales	68525|delta/epsilon subdivisions	L	PFAM transposase IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
k59_65462_1	1123371.ATXH01000031_gene2145	1.21e-61	209.0	COG0210@1|root,COG0210@2|Bacteria,2GGRZ@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	L	UvrD-like helicase C-terminal domain	-	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DUF3553,UvrD-helicase,UvrD_C
k59_172496_1	716928.AJQT01000047_gene2149	7.04e-103	315.0	COG1653@1|root,COG1653@2|Bacteria,1MU64@1224|Proteobacteria,2VFE8@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	Extracellular solute-binding protein	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1,SBP_bac_8
k59_210739_1	338963.Pcar_0577	3.85e-141	417.0	COG3547@1|root,COG3547@2|Bacteria,1NCHY@1224|Proteobacteria,42TM4@68525|delta/epsilon subdivisions,2WR4U@28221|Deltaproteobacteria,43W2A@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_157422_1	1265505.ATUG01000002_gene2503	3.68e-90	270.0	COG1410@1|root,COG1410@2|Bacteria,1MV6G@1224|Proteobacteria,42Q13@68525|delta/epsilon subdivisions,2WJHD@28221|Deltaproteobacteria,2MJ10@213118|Desulfobacterales	28221|Deltaproteobacteria	E	PFAM dihydropteroate synthase DHPS	-	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
k59_157422_2	1265505.ATUG01000002_gene2502	1.75e-19	84.7	COG5012@1|root,COG5012@2|Bacteria,1PXII@1224|Proteobacteria,42UWK@68525|delta/epsilon subdivisions,2X5FM@28221|Deltaproteobacteria,2MNRC@213118|Desulfobacterales	28221|Deltaproteobacteria	S	B12 binding domain	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,B12-binding_2
k59_217862_1	933262.AXAM01000030_gene825	1.65e-70	226.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42PGC@68525|delta/epsilon subdivisions,2WKHK@28221|Deltaproteobacteria,2MJ4J@213118|Desulfobacterales	28221|Deltaproteobacteria	T	ATP-binding region ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	FHA,HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Response_reg,dCache_3
## 6569 queries scanned
## Total time (seconds): 80.48154854774475
## Rate: 81.62 q/s