## Tue Sep  3 03:31:05 2024
## emapper-2.1.12
## /data/home/zhuyingjie/miniforge3/envs/eggnog/bin/emapper.py -i /data/home/zhuyingjie/01_Project/01_metagenome/salt_marsh/mmseqs_cluster/PRJNA714626/SRR13969213/SRR13969213_p_cluster_rep_seq.fasta --output PRJNA714626_SRR13969213 --data_dir /data/software/eggnog_database -m diamond --sensmode fast --output_dir /data/home/zhuyingjie/01_Project/01_metagenome/salt_marsh/annotation --temp_dir /data/software/eggnog_database/temp --excel --dbmem --cpu 24
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
k141_3742_1	1540257.JQMW01000005_gene262	1.03e-08	53.9	2DJY1@1|root,307TR@2|Bacteria,1V50J@1239|Firmicutes,24UP5@186801|Clostridia,36PW7@31979|Clostridiaceae	186801|Clostridia	S	Bacterial mobilisation protein (MobC)	-	-	-	-	-	-	-	-	-	-	-	-	MobC
k141_3742_2	1540257.JQMW01000005_gene249	3.58e-33	124.0	COG3843@1|root,COG3843@2|Bacteria,1TPRX@1239|Firmicutes,2481D@186801|Clostridia,36E9W@31979|Clostridiaceae	186801|Clostridia	U	Relaxase/Mobilisation nuclease domain	-	-	-	ko:K07126	-	-	-	-	ko00000	-	-	-	Relaxase
k141_682_1	740709.A10D4_04160	2.83e-22	98.6	COG1752@1|root,COG1752@2|Bacteria,1MUM9@1224|Proteobacteria,1RRA1@1236|Gammaproteobacteria,2QEXM@267893|Idiomarinaceae	1236|Gammaproteobacteria	S	Patatin-like phospholipase	rssA	GO:0003674,GO:0003824,GO:0016787	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
k141_2722_2	384765.SIAM614_12998	2.92e-20	94.4	COG3378@1|root,COG3378@2|Bacteria,1QV7H@1224|Proteobacteria,2TUB1@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction	-	-	-	-	-	-	-	-	-	-	-	-	PriCT_2,Prim-Pol
k141_3402_1	1304885.AUEY01000015_gene2994	2.41e-43	152.0	COG0148@1|root,COG0148@2|Bacteria,1MU1N@1224|Proteobacteria,42MS9@68525|delta/epsilon subdivisions,2WJMS@28221|Deltaproteobacteria,2MI3S@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
k141_5102_1	553220.CAMGR0001_0568	4.31e-38	146.0	2CDDI@1|root,32RXI@2|Bacteria,1N1M3@1224|Proteobacteria,42T3N@68525|delta/epsilon subdivisions,2YPE5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_683_1	177437.HRM2_31980	1.02e-27	114.0	COG0642@1|root,COG2205@2|Bacteria,1RK25@1224|Proteobacteria,42T3D@68525|delta/epsilon subdivisions,2WMAT@28221|Deltaproteobacteria,2MI6G@213118|Desulfobacterales	28221|Deltaproteobacteria	T	PFAM ATP-binding region ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
k141_2723_1	1348635.BBJY01000010_gene1340	1.18e-47	170.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,1RMWA@1236|Gammaproteobacteria,1XUDK@135623|Vibrionales	135623|Vibrionales	JKL	DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation	deaD	-	3.6.4.13	ko:K05592	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	DEAD,DbpA,Helicase_C
k141_3743_1	243277.VC_A0802	1.08e-44	162.0	COG1368@1|root,COG1368@2|Bacteria,1MVCM@1224|Proteobacteria,1RNJ3@1236|Gammaproteobacteria,1XVBR@135623|Vibrionales	135623|Vibrionales	M	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
k141_3743_2	575788.VS_1170	1.76e-18	79.0	2AWNM@1|root,31NJE@2|Bacteria,1QKA4@1224|Proteobacteria,1TIDN@1236|Gammaproteobacteria,1XYXW@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_3403_1	1304885.AUEY01000073_gene1469	6.18e-96	288.0	COG0796@1|root,COG0796@2|Bacteria,1NAI2@1224|Proteobacteria,42P58@68525|delta/epsilon subdivisions,2WKYK@28221|Deltaproteobacteria,2MIV5@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Provides the (R)-glutamate required for cell wall biosynthesis	murI	-	5.1.1.3	ko:K01776	ko00471,ko01100,map00471,map01100	-	R00260	RC00302	ko00000,ko00001,ko01000,ko01011	-	-	iAF987.Gmet_0547	Asp_Glu_race
k141_341_2	1123508.JH636443_gene4932	5.92e-85	270.0	28HTA@1|root,2Z806@2|Bacteria,2J02K@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_341_3	555779.Dthio_PD3202	1.75e-52	166.0	COG3093@1|root,COG3093@2|Bacteria,1N76J@1224|Proteobacteria,42VQB@68525|delta/epsilon subdivisions,2WRF4@28221|Deltaproteobacteria,2MD69@213115|Desulfovibrionales	28221|Deltaproteobacteria	K	TIGRFAM Addiction module antidote protein, HigA	-	-	-	ko:K21498	-	-	-	-	ko00000,ko02048	-	-	-	HTH_3
k141_341_4	96561.Dole_1386	2.85e-42	140.0	COG3549@1|root,COG3549@2|Bacteria,1MZKX@1224|Proteobacteria,42UHK@68525|delta/epsilon subdivisions,2WQDH@28221|Deltaproteobacteria,2MPR9@213118|Desulfobacterales	28221|Deltaproteobacteria	S	RelE-like toxin of type II toxin-antitoxin system HigB	-	-	-	ko:K07334	-	-	-	-	ko00000,ko02048	-	-	-	HigB-like_toxin
k141_5104_1	29495.EA26_12220	2.46e-11	73.2	COG3064@1|root,COG3209@1|root,COG3064@2|Bacteria,COG3209@2|Bacteria,1MVV1@1224|Proteobacteria,1SKYM@1236|Gammaproteobacteria,1XW76@135623|Vibrionales	135623|Vibrionales	M	COG3209 Rhs family protein	-	-	-	-	-	-	-	-	-	-	-	-	Ntox15,RHS,RHS_repeat
k141_4422_1	596151.DesfrDRAFT_2122	1.27e-46	156.0	COG1846@1|root,COG1846@2|Bacteria,1N5W3@1224|Proteobacteria,42SAX@68525|delta/epsilon subdivisions,2WPUM@28221|Deltaproteobacteria,2MDBN@213115|Desulfovibrionales	28221|Deltaproteobacteria	K	PFAM regulatory protein MarR	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
k141_4422_2	1265505.ATUG01000002_gene2274	7.29e-47	152.0	2EASK@1|root,334UK@2|Bacteria,1NFYP@1224|Proteobacteria,42WNF@68525|delta/epsilon subdivisions,2WS0H@28221|Deltaproteobacteria,2MPBX@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Branched-chain amino acid transport protein (AzlD)	-	-	-	-	-	-	-	-	-	-	-	-	AzlD
k141_4422_3	443143.GM18_0371	9.16e-84	256.0	COG1296@1|root,COG1296@2|Bacteria,1PPUP@1224|Proteobacteria,43EBT@68525|delta/epsilon subdivisions,2WUYA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	AzlC protein	-	-	-	-	-	-	-	-	-	-	-	-	AzlC
k141_4422_4	207954.MED92_09036	2.83e-26	108.0	COG2207@1|root,COG2207@2|Bacteria,1QKC9@1224|Proteobacteria,1RPJJ@1236|Gammaproteobacteria,1XHWS@135619|Oceanospirillales	135619|Oceanospirillales	K	Arac protein arabinose-binding	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18,HTH_AraC
k141_1363_1	1304885.AUEY01000008_gene2067	1.2e-175	509.0	COG0008@1|root,COG0008@2|Bacteria,1MUCR@1224|Proteobacteria,42MAI@68525|delta/epsilon subdivisions,2WJ8M@28221|Deltaproteobacteria,2MHXE@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
k141_2042_1	1219077.VAZ01S_002_00180	2.56e-24	112.0	COG1530@1|root,COG1530@2|Bacteria,1MV65@1224|Proteobacteria,1RMDS@1236|Gammaproteobacteria,1XTUQ@135623|Vibrionales	135623|Vibrionales	J	Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs	rne	-	3.1.26.12	ko:K08300	ko03018,map03018	M00394	-	-	ko00000,ko00001,ko00002,ko01000,ko03009,ko03019	-	-	-	RNase_E_G,S1
k141_2042_2	1219065.VPR01S_03_02200	5.54e-288	796.0	COG0659@1|root,COG0659@2|Bacteria,1MVWV@1224|Proteobacteria,1RMCN@1236|Gammaproteobacteria,1XSDS@135623|Vibrionales	135623|Vibrionales	P	COG0659 Sulfate permease and related transporters (MFS superfamily)	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
k141_4085_1	358220.C380_12055	7.2e-57	190.0	COG3437@1|root,COG3437@2|Bacteria,1MUB8@1224|Proteobacteria,2VH1F@28216|Betaproteobacteria,4AD3Y@80864|Comamonadaceae	28216|Betaproteobacteria	T	Response regulator containing a CheY-like receiver domain and an HD-GYP domain	-	-	-	ko:K07814	-	-	-	-	ko00000,ko02022	-	-	-	HD,HD_5,Response_reg
k141_3404_1	1121405.dsmv_2937	1.33e-12	67.4	COG2267@1|root,COG2267@2|Bacteria,1Q6AF@1224|Proteobacteria,42SE8@68525|delta/epsilon subdivisions,2X5UM@28221|Deltaproteobacteria,2MKDJ@213118|Desulfobacterales	28221|Deltaproteobacteria	I	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
k141_3404_2	525897.Dbac_1976	4.33e-94	285.0	COG1304@1|root,COG1304@2|Bacteria,1MUEZ@1224|Proteobacteria,42N2F@68525|delta/epsilon subdivisions,2WKXN@28221|Deltaproteobacteria,2M878@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	PFAM FMN-dependent alpha-hydroxy acid dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_dh
k141_4_1	1121405.dsmv_2219	4.29e-21	84.3	COG0333@1|root,COG0333@2|Bacteria,1NGM1@1224|Proteobacteria,42XHF@68525|delta/epsilon subdivisions,2WSX6@28221|Deltaproteobacteria,2MMB1@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Belongs to the bacterial ribosomal protein bL32 family	rpmF	GO:0003674,GO:0003735,GO:0005198	-	ko:K02911	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_L32p
k141_4_2	96561.Dole_2083	6.85e-22	87.0	COG0236@1|root,COG0236@2|Bacteria,1MZ4P@1224|Proteobacteria,42V9M@68525|delta/epsilon subdivisions,2WRDW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
k141_5106_2	1234679.BN424_2968	0.000293	43.1	COG1476@1|root,COG1476@2|Bacteria,1V624@1239|Firmicutes,4I3Z0@91061|Bacilli,27GXY@186828|Carnobacteriaceae	91061|Bacilli	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
k141_2043_1	55601.VANGNB10_cII0447	8.34e-51	169.0	COG4974@1|root,COG4974@2|Bacteria,1RK0K@1224|Proteobacteria,1RY57@1236|Gammaproteobacteria,1XTC1@135623|Vibrionales	135623|Vibrionales	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
k141_1703_1	96561.Dole_2568	3.31e-15	74.3	COG0284@1|root,COG0284@2|Bacteria,1MW2C@1224|Proteobacteria,42N5N@68525|delta/epsilon subdivisions,2WMJ5@28221|Deltaproteobacteria,2MHNM@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)	pyrF	GO:0003674,GO:0003824,GO:0004590,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase
k141_1703_3	1304885.AUEY01000035_gene2225	7.18e-19	83.6	COG0582@1|root,COG0582@2|Bacteria,1MVFU@1224|Proteobacteria,42RG7@68525|delta/epsilon subdivisions,2WNRB@28221|Deltaproteobacteria,2MK5U@213118|Desulfobacterales	28221|Deltaproteobacteria	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
k141_343_1	1219072.VHA01S_021_00340	7.76e-20	88.2	COG1700@1|root,COG1700@2|Bacteria,1REMQ@1224|Proteobacteria,1ST4D@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Domain of unknown function (DUF2357)	-	-	-	-	-	-	-	-	-	-	-	-	CSD,DUF2357
k141_343_2	398578.Daci_4191	1.42e-85	283.0	COG1700@1|root,COG1700@2|Bacteria,1PX6U@1224|Proteobacteria,2W12G@28216|Betaproteobacteria	28216|Betaproteobacteria	S	'Cold-shock' DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	CSD
k141_1364_1	223926.28805991	1.95e-14	67.0	2EHYU@1|root,33BQB@2|Bacteria,1NGAT@1224|Proteobacteria,1SGE4@1236|Gammaproteobacteria,1XZI3@135623|Vibrionales	135623|Vibrionales	S	Protein of unknown function (DUF2496)	C0585	-	-	-	-	-	-	-	-	-	-	-	DUF2496
k141_1364_2	1136163.M565_ctg1P0607	2.15e-06	51.2	COG3923@1|root,COG3923@2|Bacteria,1RIA6@1224|Proteobacteria,1S3Q3@1236|Gammaproteobacteria,1XX16@135623|Vibrionales	135623|Vibrionales	L	Primosomal replication protein N''	priC	-	-	ko:K04067	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	PriC
k141_4762_1	1348635.BBJY01000008_gene1780	1.02e-75	239.0	COG0628@1|root,COG0628@2|Bacteria,1MVX7@1224|Proteobacteria,1RN5Z@1236|Gammaproteobacteria,1XT37@135623|Vibrionales	135623|Vibrionales	S	permease	VP2476	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
k141_4762_3	870967.VIS19158_04766	3.35e-71	214.0	COG0316@1|root,COG0316@2|Bacteria,1RHCW@1224|Proteobacteria,1S675@1236|Gammaproteobacteria,1XXC1@135623|Vibrionales	135623|Vibrionales	C	Iron-sulfur cluster insertion protein ErpA	erpA	GO:0003674,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016043,GO:0016226,GO:0019538,GO:0022607,GO:0031163,GO:0043167,GO:0043169,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0048037,GO:0051186,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0051604,GO:0071704,GO:0071840,GO:1901564	-	ko:K15724	-	-	-	-	ko00000	-	-	-	Fe-S_biosyn
k141_4762_4	1187848.AJYQ01000127_gene621	3.64e-217	608.0	COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,1RM7S@1236|Gammaproteobacteria,1XUZ4@135623|Vibrionales	135623|Vibrionales	M	COG0739 Membrane proteins related to metalloendopeptidases	yebA	-	-	-	-	-	-	-	-	-	-	-	OapA,OapA_N,Peptidase_M23
k141_3744_1	1304885.AUEY01000005_gene817	2.58e-128	372.0	COG0280@1|root,COG0280@2|Bacteria,1QTS5@1224|Proteobacteria,42MPY@68525|delta/epsilon subdivisions,2WJ2V@28221|Deltaproteobacteria,2MJGM@213118|Desulfobacterales	28221|Deltaproteobacteria	C	belongs to the CobB CobQ family	pta	-	2.3.1.8	ko:K00625,ko:K13788	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00230,R00921	RC00004,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1035	AAA_26,DRTGG,PTA_PTB
k141_3744_2	1304885.AUEY01000005_gene816	7.49e-211	590.0	COG0282@1|root,COG0282@2|Bacteria,1MW61@1224|Proteobacteria,42MJA@68525|delta/epsilon subdivisions,2WJBJ@28221|Deltaproteobacteria,2MIMM@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction	ackA	-	2.7.2.1	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00315,R01353	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1034	Acetate_kinase
k141_4088_2	1265505.ATUG01000001_gene4750	9.86e-62	198.0	COG0679@1|root,COG0679@2|Bacteria,1N1X9@1224|Proteobacteria,42R83@68525|delta/epsilon subdivisions,2WN00@28221|Deltaproteobacteria,2MJHD@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Membrane transport protein	-	-	-	ko:K07088	-	-	-	-	ko00000	-	-	-	Mem_trans
k141_4424_1	675815.VOA_002575	2.32e-05	45.4	COG0587@1|root,COG0587@2|Bacteria,1MUIF@1224|Proteobacteria,1RP0K@1236|Gammaproteobacteria,1XTXD@135623|Vibrionales	135623|Vibrionales	L	COG0587 DNA polymerase III, alpha subunit	dnaE	GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032991,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
k141_4424_2	1219065.VPR01S_10_00540	1.6e-202	563.0	COG0825@1|root,COG0825@2|Bacteria,1MURN@1224|Proteobacteria,1RNN8@1236|Gammaproteobacteria,1XU3J@135623|Vibrionales	135623|Vibrionales	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA	accA	GO:0003674,GO:0003824,GO:0003989,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009317,GO:0009987,GO:0016053,GO:0016421,GO:0016874,GO:0016885,GO:0019752,GO:0032787,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901576,GO:1902494	2.1.3.15,6.4.1.2	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	ACCA
k141_4424_3	55601.VANGNB10_cI2030c	3.02e-119	358.0	COG0037@1|root,COG0037@2|Bacteria,1MU85@1224|Proteobacteria,1RN14@1236|Gammaproteobacteria,1XTTB@135623|Vibrionales	135623|Vibrionales	J	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	6.3.4.19	ko:K04075	-	-	R09597	RC02633,RC02634	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3,TilS,TilS_C
k141_684_1	590409.Dd586_3371	6.05e-126	372.0	COG1609@1|root,COG1609@2|Bacteria,1NNJH@1224|Proteobacteria,1RRMH@1236|Gammaproteobacteria,2JEYK@204037|Dickeya	1236|Gammaproteobacteria	K	helix_turn _helix lactose operon repressor	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
k141_684_2	1355374.JARU01000016_gene970	2.78e-47	164.0	2DBB6@1|root,2Z85M@2|Bacteria,1QMDX@1224|Proteobacteria,42QTF@68525|delta/epsilon subdivisions,2YP1H@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_684_3	1415755.JQLV01000001_gene1514	2.01e-173	497.0	COG1914@1|root,COG1914@2|Bacteria,1MW6X@1224|Proteobacteria,1RNA2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	H( )-stimulated, divalent metal cation uptake system	mntH	-	-	-	-	-	-	-	-	-	-	-	Nramp
k141_4763_1	1348635.BBJY01000029_gene2057	2.74e-62	202.0	COG2017@1|root,COG2017@2|Bacteria,1MVUY@1224|Proteobacteria,1RQ29@1236|Gammaproteobacteria,1Y214@135623|Vibrionales	135623|Vibrionales	G	Domain of unknown function (DUF4432)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4432
k141_4763_2	243277.VC_A0917	3.62e-54	175.0	COG1309@1|root,COG1309@2|Bacteria,1P117@1224|Proteobacteria,1SIAW@1236|Gammaproteobacteria,1XWYZ@135623|Vibrionales	135623|Vibrionales	K	Transcriptional regulator	luxT	-	-	-	-	-	-	-	-	-	-	-	TetR_N
k141_1704_1	1444306.JFZC01000041_gene54	5.46e-106	319.0	COG0697@1|root,COG0697@2|Bacteria,1UHT1@1239|Firmicutes,4HCWY@91061|Bacilli	91061|Bacilli	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
k141_3745_1	221288.JH992901_gene2610	7.15e-14	65.9	28UR4@1|root,2ZGVF@2|Bacteria,1GFWN@1117|Cyanobacteria,1JMMZ@1189|Stigonemataceae	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_7_2	945550.VISI1226_06598	1.73e-05	53.1	COG0811@1|root,COG0811@2|Bacteria,1RKWW@1224|Proteobacteria,1S6BX@1236|Gammaproteobacteria,1XTHB@135623|Vibrionales	135623|Vibrionales	U	MotA/TolQ/ExbB proton channel family	exbB1	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0017038,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
k141_4765_1	1121413.JMKT01000014_gene2444	2.6e-75	241.0	COG0753@1|root,COG0753@2|Bacteria,1MUXZ@1224|Proteobacteria,42MIN@68525|delta/epsilon subdivisions,2WJC5@28221|Deltaproteobacteria,2M91H@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	Belongs to the catalase family	katA	-	1.11.1.6	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	M00532	R00009,R00602,R02670	RC00034,RC00767,RC02141,RC02755	ko00000,ko00001,ko00002,ko01000	-	-	-	Catalase,Catalase-rel
k141_3063_1	1121935.AQXX01000134_gene3648	2.34e-232	674.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,1XHQA@135619|Oceanospirillales	135619|Oceanospirillales	T	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal,dCache_1
k141_3063_2	1219076.N646_3911	0.0	979.0	COG3243@1|root,COG3243@2|Bacteria,1MU68@1224|Proteobacteria,1RPVQ@1236|Gammaproteobacteria,1XUBI@135623|Vibrionales	135623|Vibrionales	I	Polyhydroxyalkanoic acid synthase	phaC	-	-	ko:K03821	ko00650,map00650	-	R04254	RC00004	ko00000,ko00001,ko01000	-	-	-	PhaC_N
k141_3063_3	1116375.VEJY3_17611	1.92e-32	117.0	2C668@1|root,32W8B@2|Bacteria,1N0CT@1224|Proteobacteria,1SA1B@1236|Gammaproteobacteria,1XXAJ@135623|Vibrionales	135623|Vibrionales	S	Phasin protein	-	-	-	-	-	-	-	-	-	-	-	-	Phasin_2
k141_4428_1	292563.Cyast_2140	1.68e-46	171.0	COG0515@1|root,COG2199@1|root,COG2203@1|root,COG3899@1|root,COG0515@2|Bacteria,COG2203@2|Bacteria,COG3706@2|Bacteria,COG3899@2|Bacteria,1GBKM@1117|Cyanobacteria	1117|Cyanobacteria	KLT	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GAF,GGDEF,HATPase_c,HisKA,PAS_3,PAS_4,Pkinase,Response_reg,SpoIIE
k141_4089_1	1347086.CCBA010000009_gene1374	1.31e-38	135.0	COG1788@1|root,COG1788@2|Bacteria,1V21Q@1239|Firmicutes,4HB3E@91061|Bacilli,1ZCXP@1386|Bacillus	91061|Bacilli	I	COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit	ctfA	-	2.8.3.8,2.8.3.9	ko:K01034	ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020	-	R01179,R01359,R01365,R07832	RC00012,RC00014	ko00000,ko00001,ko01000	-	-	-	CoA_trans
k141_4089_2	318464.IO99_16435	6.54e-88	265.0	COG2057@1|root,COG2057@2|Bacteria,1TNY5@1239|Firmicutes,247ZM@186801|Clostridia,36GAR@31979|Clostridiaceae	186801|Clostridia	I	3-oxoacid CoA-transferase, B subunit	ctfB1	-	2.8.3.5,2.8.3.8,2.8.3.9	ko:K01029,ko:K01035	ko00072,ko00280,ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00072,map00280,map00310,map00627,map00640,map00650,map01100,map01120,map02020	-	R00410,R01179,R01359,R01365,R07832	RC00012,RC00014	ko00000,ko00001,ko01000	-	-	-	CoA_trans
k141_685_2	1121403.AUCV01000029_gene2726	3.77e-58	182.0	COG0662@1|root,COG0662@2|Bacteria,1RHWU@1224|Proteobacteria,42U1Z@68525|delta/epsilon subdivisions,2WQ05@28221|Deltaproteobacteria,2MNWP@213118|Desulfobacterales	28221|Deltaproteobacteria	G	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
k141_8_2	265729.GS18_0209115	5.17e-12	66.2	COG0702@1|root,COG0702@2|Bacteria,1V112@1239|Firmicutes,4HEVN@91061|Bacilli,1ZG8I@1386|Bacillus	91061|Bacilli	GM	NAD(P)H-binding	M1-688	-	-	-	-	-	-	-	-	-	-	-	Epimerase,HIM1,NAD_binding_10
k141_8_3	637905.SVI_0386	1.85e-14	71.2	COG0702@1|root,COG0702@2|Bacteria,1MZG7@1224|Proteobacteria,1S39N@1236|Gammaproteobacteria,2QEEU@267890|Shewanellaceae	1236|Gammaproteobacteria	GM	Nucleoside-diphosphate-sugar epimerases	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase,NAD_binding_10
k141_4766_1	933262.AXAM01000073_gene3356	2.6e-39	137.0	COG0242@1|root,COG0242@2|Bacteria,1RA2P@1224|Proteobacteria,42RFN@68525|delta/epsilon subdivisions,2WP25@28221|Deltaproteobacteria,2MJU0@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
k141_4766_2	635013.TherJR_1796	1.3e-36	133.0	COG0223@1|root,COG0223@2|Bacteria,1TQ32@1239|Firmicutes,248ED@186801|Clostridia,260EN@186807|Peptococcaceae	186801|Clostridia	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	-	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
k141_3747_1	870967.VIS19158_18546	5.05e-95	292.0	COG3395@1|root,COG3395@2|Bacteria,1MW4G@1224|Proteobacteria,1RN8I@1236|Gammaproteobacteria,1XV5M@135623|Vibrionales	135623|Vibrionales	S	Putative nucleotide-binding of sugar-metabolising enzyme	-	-	2.7.1.217	ko:K21948	-	-	R11706,R11707	-	ko00000,ko01000	-	-	-	DUF1357_C,DUF1537
k141_690_1	1121405.dsmv_2140	5.67e-49	167.0	COG1762@1|root,COG1762@2|Bacteria,1RG0Z@1224|Proteobacteria,42RSF@68525|delta/epsilon subdivisions,2WNXB@28221|Deltaproteobacteria,2MJZ1@213118|Desulfobacterales	28221|Deltaproteobacteria	GT	PFAM phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2	-	-	-	ko:K02806	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	-	-	-	HTH_17,PTS_EIIA_2
k141_690_2	1121405.dsmv_2139	9.2e-232	659.0	COG0038@1|root,COG0517@1|root,COG0038@2|Bacteria,COG0517@2|Bacteria,1MV4K@1224|Proteobacteria,42PJQ@68525|delta/epsilon subdivisions,2WKR4@28221|Deltaproteobacteria,2MIMH@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Voltage gated chloride channel	-	-	-	ko:K03281	-	-	-	-	ko00000	2.A.49	-	-	CBS,Voltage_CLC
k141_690_3	177437.HRM2_16410	1.54e-66	212.0	COG0589@1|root,COG0589@2|Bacteria,1R51N@1224|Proteobacteria,42PVP@68525|delta/epsilon subdivisions,2WKQB@28221|Deltaproteobacteria,2MINR@213118|Desulfobacterales	28221|Deltaproteobacteria	T	response to stress	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_1709_1	1235800.C819_03203	9.25e-68	229.0	COG0178@1|root,COG0178@2|Bacteria,1TPIJ@1239|Firmicutes,2485F@186801|Clostridia,27J00@186928|unclassified Lachnospiraceae	186801|Clostridia	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
k141_2385_1	1280001.BAOA01000077_gene3083	1.81e-112	335.0	COG1648@1|root,COG1648@2|Bacteria,1RB3H@1224|Proteobacteria,1SPHW@1236|Gammaproteobacteria,1XT8S@135623|Vibrionales	135623|Vibrionales	H	COG1648 Siroheme synthase (precorrin-2 oxidase ferrochelatase domain)	cysG	-	1.3.1.76,4.99.1.4	ko:K02304	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03947	RC01012,RC01034	ko00000,ko00001,ko00002,ko01000	-	-	-	CysG_dimeriser,NAD_binding_7,Sirohm_synth_M
k141_1035_1	338963.Pcar_3003	3.02e-78	266.0	COG1538@1|root,COG1538@2|Bacteria,1MYXE@1224|Proteobacteria,42TA7@68525|delta/epsilon subdivisions,2WR7T@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
k141_182_1	1191299.AJYX01000055_gene2133	1.29e-141	412.0	COG2017@1|root,COG2017@2|Bacteria,1MVMN@1224|Proteobacteria,1RNZN@1236|Gammaproteobacteria,1XTI3@135623|Vibrionales	135623|Vibrionales	G	Converts alpha-aldose to the beta-anomer	galM	-	5.1.3.3	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	M00632	R01602,R10619	RC00563	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldose_epim
k141_182_2	675806.VII_002057	3.5e-102	311.0	COG0457@1|root,COG0457@2|Bacteria,1NFC8@1224|Proteobacteria,1RWMG@1236|Gammaproteobacteria,1XVGU@135623|Vibrionales	135623|Vibrionales	S	COG0457 FOG TPR repeat	VP2409	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_16,TPR_17,TPR_2,TPR_8
k141_182_3	1051646.VITU9109_21869	2.9e-126	370.0	COG2064@1|root,COG2064@2|Bacteria,1MWAZ@1224|Proteobacteria,1SZWZ@1236|Gammaproteobacteria,1XSF0@135623|Vibrionales	135623|Vibrionales	NU	COG2064 Flp pilus assembly protein TadC	VV2651	-	-	ko:K12511	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF
k141_182_4	675816.VIA_002113	7.19e-140	405.0	COG4965@1|root,COG4965@2|Bacteria,1MUXK@1224|Proteobacteria,1S1QN@1236|Gammaproteobacteria,1XVM8@135623|Vibrionales	135623|Vibrionales	U	COG4965 Flp pilus assembly protein TadB	-	-	-	ko:K12510	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF
k141_182_5	672.VV93_v1c23710	6.26e-267	741.0	COG4962@1|root,COG4962@2|Bacteria,1R7EN@1224|Proteobacteria,1RP9G@1236|Gammaproteobacteria,1XSF1@135623|Vibrionales	135623|Vibrionales	U	COG4962 Flp pilus assembly protein, ATPase CpaF	-	-	-	ko:K02283	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSE
k141_182_6	1219080.VEZ01S_47_00240	8.94e-110	335.0	COG4963@1|root,COG4963@2|Bacteria,1MWNY@1224|Proteobacteria,1S6CE@1236|Gammaproteobacteria,1XVBI@135623|Vibrionales	135623|Vibrionales	U	COG4963 Flp pilus assembly protein, ATPase CpaE	-	-	-	ko:K02282	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	AAA_31
k141_182_7	870967.VIS19158_05313	4.68e-25	101.0	COG4961@1|root,COG4961@2|Bacteria,1PRDK@1224|Proteobacteria,1TC3B@1236|Gammaproteobacteria,1XYH0@135623|Vibrionales	135623|Vibrionales	U	TadE-like protein	VP2414	-	-	-	-	-	-	-	-	-	-	-	TadE
k141_182_9	1051646.VITU9109_21839	1.42e-76	251.0	COG4961@1|root,COG4961@2|Bacteria,1R58C@1224|Proteobacteria,1S1A4@1236|Gammaproteobacteria,1XWG5@135623|Vibrionales	135623|Vibrionales	U	Putative Flp pilus-assembly TadE/G-like	-	-	-	-	-	-	-	-	-	-	-	-	Tad
k141_182_10	672.VV93_v1c23760	2.27e-19	81.6	2AWMU@1|root,31NIJ@2|Bacteria,1QK98@1224|Proteobacteria,1TICP@1236|Gammaproteobacteria,1XYVM@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_182_11	672.VV93_v1c23770	3.31e-233	655.0	COG4964@1|root,COG4964@2|Bacteria,1MV8G@1224|Proteobacteria,1RQ4U@1236|Gammaproteobacteria,1XU4G@135623|Vibrionales	135623|Vibrionales	U	Belongs to the GSP D family	-	-	-	ko:K02280	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	BON,Secretin,T2SS-T3SS_pil_N
k141_182_12	945550.VISI1226_15781	4.2e-117	342.0	COG3745@1|root,COG3745@2|Bacteria,1MW75@1224|Proteobacteria,1S6EP@1236|Gammaproteobacteria,1XT4T@135623|Vibrionales	135623|Vibrionales	U	COG3745 Flp pilus assembly protein CpaB	VV2661	-	-	ko:K02279	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	RcpC,SAF
k141_182_13	1348635.BBJY01000008_gene1750	3.22e-230	644.0	COG0714@1|root,COG0714@2|Bacteria,1QUGB@1224|Proteobacteria,1T1Y2@1236|Gammaproteobacteria,1XSEK@135623|Vibrionales	135623|Vibrionales	S	ATPase with chaperone activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_182_14	945550.VISI1226_15791	1.28e-23	99.0	COG4960@1|root,COG4960@2|Bacteria,1QKFB@1224|Proteobacteria,1TIJ8@1236|Gammaproteobacteria,1XZ89@135623|Vibrionales	135623|Vibrionales	OU	COG4960 Flp pilus assembly protein, protease CpaA	-	-	3.4.23.43	ko:K02278	-	-	-	-	ko00000,ko01000,ko02035,ko02044	-	-	-	Peptidase_A24
k141_182_15	575788.VS_2447	6.65e-14	65.9	2BBNH@1|root,3256H@2|Bacteria,1QKCP@1224|Proteobacteria,1TIG6@1236|Gammaproteobacteria,1XZ2Q@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	ko:K02651	ko04112,map04112	-	-	-	ko00000,ko00001,ko02035,ko02044	-	-	-	-
k141_182_16	153721.MYP_2854	3.56e-06	55.5	COG2207@1|root,COG2207@2|Bacteria,4NM90@976|Bacteroidetes,47PQV@768503|Cytophagia	976|Bacteroidetes	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
k141_182_17	675806.VII_001517	2.08e-108	330.0	COG2203@1|root,COG2206@1|root,COG2203@2|Bacteria,COG2206@2|Bacteria,1RAQS@1224|Proteobacteria,1T1XS@1236|Gammaproteobacteria,1XUFB@135623|Vibrionales	135623|Vibrionales	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HD_5
k141_182_18	335659.S23_32520	1.29e-07	59.7	COG2207@1|root,COG2207@2|Bacteria,1QUXX@1224|Proteobacteria,2VF4V@28211|Alphaproteobacteria,3JYAV@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	K	AraC-binding-like domain	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding_2,HTH_18
k141_182_19	345073.VC395_2456	4.44e-261	732.0	COG1022@1|root,COG1022@2|Bacteria,1MU4D@1224|Proteobacteria,1RPNE@1236|Gammaproteobacteria,1XTZV@135623|Vibrionales	135623|Vibrionales	I	COG1022 Long-chain acyl-CoA synthetases (AMP-forming)	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
k141_182_22	55601.VANGNB10_cI2123	7.17e-304	858.0	2C5UW@1|root,2Z80T@2|Bacteria,1MXH2@1224|Proteobacteria,1RR1H@1236|Gammaproteobacteria,1XU04@135623|Vibrionales	135623|Vibrionales	S	PilZ domain	-	-	-	-	-	-	-	-	-	-	-	-	PilZ
k141_182_23	223926.28807429	1.11e-152	438.0	COG0560@1|root,COG0560@2|Bacteria,1MWA3@1224|Proteobacteria,1RNJE@1236|Gammaproteobacteria,1XTII@135623|Vibrionales	135623|Vibrionales	E	phosphoserine phosphatase	serB	GO:0001505,GO:0003674,GO:0003824,GO:0004647,GO:0006082,GO:0006520,GO:0006544,GO:0006545,GO:0006563,GO:0006564,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0017144,GO:0019752,GO:0042133,GO:0042136,GO:0042578,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	3.1.3.3	ko:K01079	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R00582	RC00017	ko00000,ko00001,ko00002,ko01000,ko01009	-	-	-	HAD,Hydrolase
k141_182_24	345073.VC395_2461	2.63e-93	278.0	COG3726@1|root,COG3726@2|Bacteria,1MUT6@1224|Proteobacteria,1RNHZ@1236|Gammaproteobacteria,1XT32@135623|Vibrionales	135623|Vibrionales	S	membrane protein affecting hemolysin expression	smp	-	-	ko:K07186	-	-	-	-	ko00000	-	-	-	SMP_2
k141_182_26	1280001.BAOA01000059_gene2256	6.86e-116	339.0	COG0274@1|root,COG0274@2|Bacteria,1N8AG@1224|Proteobacteria,1RPTS@1236|Gammaproteobacteria,1XTNE@135623|Vibrionales	135623|Vibrionales	F	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate	deoC	GO:0003674,GO:0003824,GO:0004139,GO:0005975,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009262,GO:0009264,GO:0009987,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576	4.1.2.4	ko:K01619	ko00030,map00030	-	R01066	RC00436,RC00437	ko00000,ko00001,ko01000	-	-	-	DeoC
k141_182_27	945550.VISI1226_07747	1.63e-192	546.0	COG1972@1|root,COG1972@2|Bacteria,1MXXX@1224|Proteobacteria,1RMBX@1236|Gammaproteobacteria,1XSKX@135623|Vibrionales	135623|Vibrionales	U	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family	-	-	-	ko:K03317	-	-	-	-	ko00000	2.A.41	-	-	Gate,Nucleos_tra2_C,Nucleos_tra2_N
k141_182_28	243277.VC_2353	5.53e-83	258.0	COG0084@1|root,COG0084@2|Bacteria,1MW5C@1224|Proteobacteria,1RP5T@1236|Gammaproteobacteria,1XUGD@135623|Vibrionales	135623|Vibrionales	L	COG0084 Mg-dependent DNase	yjjV	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
k141_182_29	55601.VANGNB10_cI2132c	3.66e-135	388.0	COG3022@1|root,COG3022@2|Bacteria,1MUAF@1224|Proteobacteria,1RMTD@1236|Gammaproteobacteria,1XUFU@135623|Vibrionales	135623|Vibrionales	S	Belongs to the UPF0246 family	yaaA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0033194,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:1901700	-	ko:K09861	-	-	-	-	ko00000	-	-	-	H2O2_YaaD
k141_182_30	55601.VANGNB10_cI2133c	3.95e-268	743.0	COG1115@1|root,COG1115@2|Bacteria,1MUI3@1224|Proteobacteria,1RMNF@1236|Gammaproteobacteria,1XTS9@135623|Vibrionales	135623|Vibrionales	U	alanine symporter	yaaJ	-	-	ko:K03310	-	-	-	-	ko00000	2.A.25	-	-	Na_Ala_symp
k141_182_31	243277.VC_2357	1.35e-24	93.6	2EJCD@1|root,33D3F@2|Bacteria,1NGUI@1224|Proteobacteria,1SHIH@1236|Gammaproteobacteria,1XZ06@135623|Vibrionales	135623|Vibrionales	S	Protein of unknown function (DUF3545)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3545
k141_182_32	945550.VISI1226_07717	2.1e-74	228.0	COG3945@1|root,COG3945@2|Bacteria,1NDGV@1224|Proteobacteria,1SGA3@1236|Gammaproteobacteria,1XWZS@135623|Vibrionales	135623|Vibrionales	S	Hemerythrin HHE cation binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin
k141_182_33	1348635.BBJY01000002_gene3548	3.17e-136	389.0	COG0692@1|root,COG0692@2|Bacteria,1MV80@1224|Proteobacteria,1RPDH@1236|Gammaproteobacteria,1XU4K@135623|Vibrionales	135623|Vibrionales	L	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine	ung	GO:0003674,GO:0003824,GO:0004844,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0097510,GO:0140097,GO:1901360	3.2.2.27	ko:K03648	ko03410,ko05340,map03410,map05340	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
k141_182_35	945550.VISI1226_07702	3.28e-64	198.0	COG3445@1|root,COG3445@2|Bacteria,1RDRB@1224|Proteobacteria,1S45G@1236|Gammaproteobacteria,1XX0C@135623|Vibrionales	135623|Vibrionales	S	Acts as a radical domain for damaged PFL and possibly other radical proteins	grcA	GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006566,GO:0006567,GO:0006807,GO:0008150,GO:0008152,GO:0008861,GO:0009056,GO:0009063,GO:0009066,GO:0009068,GO:0009987,GO:0016054,GO:0016407,GO:0016408,GO:0016453,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	-	ko:K06866	-	-	-	-	ko00000	-	-	-	Gly_radical
k141_182_37	1238450.VIBNISOn1_800060	6.39e-268	738.0	COG0498@1|root,COG0498@2|Bacteria,1MUWQ@1224|Proteobacteria,1RQ0H@1236|Gammaproteobacteria,1XT55@135623|Vibrionales	135623|Vibrionales	E	Threonine synthase	thrC	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP,Thr_synth_N
k141_182_38	1348635.BBJY01000002_gene3553	3.14e-195	545.0	COG0083@1|root,COG0083@2|Bacteria,1MW8I@1224|Proteobacteria,1RMYR@1236|Gammaproteobacteria,1XU46@135623|Vibrionales	135623|Vibrionales	F	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate	thrB	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004413,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006555,GO:0006566,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009088,GO:0009092,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.1.39	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	M00018	R01771	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
k141_3863_6	177439.DP1277	1.92e-103	313.0	COG1966@1|root,COG1966@2|Bacteria,1MWF9@1224|Proteobacteria,42NBI@68525|delta/epsilon subdivisions,2WKNF@28221|Deltaproteobacteria,2MPY5@213118|Desulfobacterales	28221|Deltaproteobacteria	T	5TM C-terminal transporter carbon starvation CstA	-	-	-	-	-	-	-	-	-	-	-	-	CstA,CstA_5TM
k141_3194_1	113355.CM001775_gene2373	7.15e-143	425.0	28PYV@1|root,2ZCIC@2|Bacteria,1GBG4@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_2161_2	1410653.JHVC01000032_gene1037	1.31e-84	270.0	COG5492@1|root,COG5492@2|Bacteria,1W2KG@1239|Firmicutes,24FQ5@186801|Clostridia,36E2B@31979|Clostridiaceae	186801|Clostridia	N	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_2161_3	1410653.JHVC01000032_gene1037	9.41e-84	268.0	COG5492@1|root,COG5492@2|Bacteria,1W2KG@1239|Firmicutes,24FQ5@186801|Clostridia,36E2B@31979|Clostridiaceae	186801|Clostridia	N	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_2161_4	1410653.JHVC01000032_gene1037	1.38e-89	283.0	COG5492@1|root,COG5492@2|Bacteria,1W2KG@1239|Firmicutes,24FQ5@186801|Clostridia,36E2B@31979|Clostridiaceae	186801|Clostridia	N	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_2161_5	1121342.AUCO01000009_gene415	4.47e-56	179.0	COG1342@1|root,COG1342@2|Bacteria,1V5RE@1239|Firmicutes,25CFP@186801|Clostridia,36I1U@31979|Clostridiaceae	186801|Clostridia	S	Belongs to the UPF0251 family	-	-	-	-	-	-	-	-	-	-	-	-	DUF134
k141_2161_6	572480.Arnit_2447	1.7e-14	73.9	COG0735@1|root,COG0735@2|Bacteria,1RDWJ@1224|Proteobacteria,42MN8@68525|delta/epsilon subdivisions,2YPGX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Belongs to the Fur family	fur	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
k141_2161_7	1121289.JHVL01000017_gene775	5.2e-42	141.0	COG1433@1|root,COG1433@2|Bacteria,1TRMQ@1239|Firmicutes,24BUF@186801|Clostridia,36JK4@31979|Clostridiaceae	186801|Clostridia	S	Dinitrogenase iron-molybdenum cofactor	-	-	-	-	-	-	-	-	-	-	-	-	Nitro_FeMo-Co
k141_2161_8	1121324.CLIT_5c01190	8.05e-77	242.0	COG1149@1|root,COG1149@2|Bacteria,1TQI9@1239|Firmicutes,2484J@186801|Clostridia	186801|Clostridia	C	CobQ CobB MinD ParA nucleotide binding domain	-	-	-	-	-	-	-	-	-	-	-	-	CbiA,Fer4
k141_2161_9	720554.Clocl_0167	6.82e-81	252.0	COG1149@1|root,COG1149@2|Bacteria,1TP7Y@1239|Firmicutes,249ER@186801|Clostridia,3WMUC@541000|Ruminococcaceae	186801|Clostridia	C	CobQ/CobB/MinD/ParA nucleotide binding domain	-	-	-	-	-	-	-	-	-	-	-	-	CbiA,Fer4,ParA
k141_2161_10	398512.JQKC01000001_gene2289	8.35e-26	100.0	COG1433@1|root,COG1433@2|Bacteria,1VFDZ@1239|Firmicutes,24R8N@186801|Clostridia,3WM0B@541000|Ruminococcaceae	186801|Clostridia	S	Dinitrogenase iron-molybdenum cofactor	-	-	-	-	-	-	-	-	-	-	-	-	Nitro_FeMo-Co
k141_2161_11	1291050.JAGE01000002_gene3888	3.05e-99	303.0	COG0489@1|root,COG0489@2|Bacteria,1TQ34@1239|Firmicutes,24817@186801|Clostridia,3WGBQ@541000|Ruminococcaceae	186801|Clostridia	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	-	-	-	-	-	-	-	-	-	-	-	-	Nitro_FeMo-Co,ParA
k141_2161_12	1449063.JMLS01000029_gene515	6.26e-40	136.0	COG2201@1|root,COG2201@2|Bacteria	2|Bacteria	NT	protein-glutamate methylesterase activity	cheB	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	3.1.1.61,3.5.1.44	ko:K03412,ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,Response_reg
k141_2161_13	1304284.L21TH_0079	0.0	1526.0	COG1057@1|root,COG1057@2|Bacteria,1TQVJ@1239|Firmicutes,249M0@186801|Clostridia,36DM4@31979|Clostridiaceae	186801|Clostridia	H	Cytidylyltransferase-like	-	-	-	-	-	-	-	-	-	-	-	-	CTP_transf_like
k141_2161_14	536227.CcarbDRAFT_2863	4.07e-87	278.0	COG0039@1|root,COG0039@2|Bacteria,1TQIV@1239|Firmicutes,248DK@186801|Clostridia,36GJF@31979|Clostridiaceae	186801|Clostridia	C	lactate/malate dehydrogenase, NAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Ldh_1_N
k141_2161_15	941824.TCEL_01683	8.48e-106	321.0	COG0431@1|root,COG0431@2|Bacteria,1UYKJ@1239|Firmicutes,2485E@186801|Clostridia,36E7N@31979|Clostridiaceae	186801|Clostridia	S	NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
k141_2161_16	272563.CD630_25250	2.07e-29	114.0	COG2137@1|root,COG2137@2|Bacteria,1V72V@1239|Firmicutes,24KZH@186801|Clostridia,25RI7@186804|Peptostreptococcaceae	186801|Clostridia	S	Modulates RecA activity	recX	-	-	ko:K03565	-	-	-	-	ko00000,ko03400	-	-	-	RecX
k141_2161_17	536227.CcarbDRAFT_3209	2.95e-35	139.0	COG2206@1|root,COG2206@2|Bacteria,1TR95@1239|Firmicutes,25AZS@186801|Clostridia,36ECN@31979|Clostridiaceae	186801|Clostridia	T	PFAM metal-dependent phosphohydrolase HD sub domain	-	-	-	-	-	-	-	-	-	-	-	-	HD,HD_5
k141_2161_18	1410622.JNKY01000012_gene2093	0.000199	43.5	COG1925@1|root,COG1925@2|Bacteria,1TTT1@1239|Firmicutes,24PF9@186801|Clostridia,27PIE@186928|unclassified Lachnospiraceae	186801|Clostridia	G	PTS HPr component phosphorylation site	-	-	-	ko:K11189	-	-	-	-	ko00000,ko02000	4.A.2.1	-	-	PTS-HPr
k141_2161_19	332101.JIBU02000023_gene4770	0.0	1045.0	COG0058@1|root,COG0058@2|Bacteria,1TQAJ@1239|Firmicutes,248E1@186801|Clostridia,36E5W@31979|Clostridiaceae	186801|Clostridia	G	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties	glgP	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	Phosphorylase
k141_2161_20	1408439.JHXW01000002_gene474	7.48e-195	557.0	COG0297@1|root,COG0297@2|Bacteria,378FM@32066|Fusobacteria	32066|Fusobacteria	G	Synthesizes alpha-1,4-glucan chains using ADP-glucose	glgA	GO:0003674,GO:0003824,GO:0016740,GO:0016757	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Glyco_transf_5,Glycos_transf_1
k141_2161_21	1391646.AVSU01000017_gene3102	3.5e-101	311.0	COG0448@1|root,COG0448@2|Bacteria,1TPZ3@1239|Firmicutes,2482Q@186801|Clostridia,25QUP@186804|Peptostreptococcaceae	186801|Clostridia	G	Glucose-1-phosphate adenylyltransferase, GlgD subunit	glgD	-	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
k141_2161_22	290402.Cbei_4905	2e-168	482.0	COG0448@1|root,COG0448@2|Bacteria,1TNZW@1239|Firmicutes,24943@186801|Clostridia,36DKC@31979|Clostridiaceae	186801|Clostridia	H	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans	glgC	-	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
k141_2161_23	1121324.CLIT_5c00440	2.02e-281	791.0	COG0296@1|root,COG0296@2|Bacteria,1TP4M@1239|Firmicutes,247WH@186801|Clostridia,25QUV@186804|Peptostreptococcaceae	186801|Clostridia	G	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position	glgB	-	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_48
k141_2161_24	1408304.JAHA01000008_gene1658	3.15e-62	221.0	COG0265@1|root,COG0265@2|Bacteria,1TRM8@1239|Firmicutes,247M5@186801|Clostridia,4BWP8@830|Butyrivibrio	186801|Clostridia	O	Trypsin	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
k141_2161_25	1280664.AUIX01000022_gene1427	5.75e-62	216.0	COG2770@1|root,COG5002@1|root,COG2770@2|Bacteria,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,247VG@186801|Clostridia,4BXA8@830|Butyrivibrio	186801|Clostridia	T	GHKL domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
k141_2161_26	929506.CbC4_0146	2.4e-86	262.0	COG0745@1|root,COG0745@2|Bacteria,1TPZ0@1239|Firmicutes,249IC@186801|Clostridia,36EQW@31979|Clostridiaceae	186801|Clostridia	KT	response regulator	resD	-	-	ko:K07668,ko:K07775	ko02020,map02020	M00458,M00459	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
k141_2161_28	484770.UFO1_1632	2.51e-84	262.0	COG1732@1|root,COG1732@2|Bacteria,1TQ7D@1239|Firmicutes,4H29N@909932|Negativicutes	909932|Negativicutes	P	ABC transporter, substrate-binding protein, QAT family	proWX	-	-	ko:K05845,ko:K05846	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	BPD_transp_1,OpuAC
k141_2161_29	1511.CLOST_1010	1.59e-162	471.0	COG3263@1|root,COG3263@2|Bacteria,1TQPJ@1239|Firmicutes,2486W@186801|Clostridia	186801|Clostridia	P	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
k141_2161_30	1033737.CAEV01000022_gene3301	6.41e-91	268.0	2C91C@1|root,30CC5@2|Bacteria,1V1Z2@1239|Firmicutes,24HJH@186801|Clostridia,36IUN@31979|Clostridiaceae	186801|Clostridia	S	Putative redox-active protein (C_GCAxxG_C_C)	-	-	-	-	-	-	-	-	-	-	-	-	C_GCAxxG_C_C
k141_2161_31	293826.Amet_3721	6.16e-83	260.0	COG1275@1|root,COG1275@2|Bacteria,1UYTE@1239|Firmicutes,2497H@186801|Clostridia,36FBE@31979|Clostridiaceae	186801|Clostridia	P	Voltage-dependent anion channel	-	-	-	ko:K11041	ko05150,map05150	-	-	-	ko00000,ko00001,ko02042	2.A.16	-	-	SLAC1
k141_2161_32	189425.PGRAT_24935	4.97e-41	146.0	COG0675@1|root,COG0675@2|Bacteria,1TT4J@1239|Firmicutes,4HEKB@91061|Bacilli,26UMB@186822|Paenibacillaceae	91061|Bacilli	L	Putative transposase DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	OrfB_IS605,OrfB_Zn_ribbon
k141_207_1	1517681.HW45_16880	6.77e-222	619.0	COG1653@1|root,COG1653@2|Bacteria,1MVMW@1224|Proteobacteria,1RRH3@1236|Gammaproteobacteria,1XV4I@135623|Vibrionales	135623|Vibrionales	G	ABC transporter	ugpB	-	-	ko:K05813	ko02010,map02010	M00198	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.3	-	-	SBP_bac_8
k141_207_2	1517681.HW45_16885	6.02e-28	108.0	COG0584@1|root,COG0584@2|Bacteria,1MU8H@1224|Proteobacteria,1RQWX@1236|Gammaproteobacteria,1Y29F@135623|Vibrionales	135623|Vibrionales	C	Glycerophosphoryl diester phosphodiesterase family	ugpQ	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
k141_1866_1	1348635.BBJY01000001_gene2471	3.81e-63	200.0	COG1433@1|root,COG1433@2|Bacteria,1PW6J@1224|Proteobacteria,1S0X4@1236|Gammaproteobacteria,1Y093@135623|Vibrionales	135623|Vibrionales	S	Dinitrogenase iron-molybdenum cofactor, N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	DIMCO_N,Nitro_FeMo-Co
k141_1866_2	1515746.HR45_08525	1.64e-37	126.0	COG5554@1|root,COG5554@2|Bacteria,1N7DQ@1224|Proteobacteria,1SD1T@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	PFAM NifT FixU	nifT	-	-	ko:K02593	-	-	-	-	ko00000	-	-	-	NifT
k141_1866_3	1348635.BBJY01000001_gene2473	0.0	908.0	COG2710@1|root,COG2710@2|Bacteria,1MWQ4@1224|Proteobacteria,1RMV3@1236|Gammaproteobacteria,1Y02M@135623|Vibrionales	135623|Vibrionales	C	Domain of unknown function (DUF3364)	-	-	1.18.6.1	ko:K02591	ko00625,ko00910,ko01100,ko01120,map00625,map00910,map01100,map01120	M00175	R05185,R05496	RC00002,RC01395,RC02891	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF3364,Oxidored_nitro
k141_1188_1	1304885.AUEY01000096_gene2843	9.35e-91	278.0	COG0697@1|root,COG0697@2|Bacteria,1MX1Y@1224|Proteobacteria,42NTW@68525|delta/epsilon subdivisions,2WMEN@28221|Deltaproteobacteria,2MJQ4@213118|Desulfobacterales	28221|Deltaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
k141_1188_2	1121396.KB893108_gene1869	2.7e-136	408.0	COG0773@1|root,COG0773@2|Bacteria,1MUC5@1224|Proteobacteria,42NMY@68525|delta/epsilon subdivisions,2WJ8S@28221|Deltaproteobacteria,2MHS5@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Belongs to the MurCDEF family	mpl	-	6.3.2.45	ko:K02558	-	-	-	-	ko00000,ko01000	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
k141_4189_1	96561.Dole_1658	7.3e-28	108.0	COG1596@1|root,COG1596@2|Bacteria,1N7GP@1224|Proteobacteria,42MNP@68525|delta/epsilon subdivisions,2WMJZ@28221|Deltaproteobacteria,2MJAM@213118|Desulfobacterales	28221|Deltaproteobacteria	M	export protein	wza2	-	-	ko:K01991	ko02026,map02026	-	-	-	ko00000,ko00001,ko02000	1.B.18	-	-	Poly_export,SLBB
k141_4189_2	96561.Dole_1657	1.63e-162	490.0	COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,1MVI9@1224|Proteobacteria,42NB4@68525|delta/epsilon subdivisions,2WK9E@28221|Deltaproteobacteria,2MHUB@213118|Desulfobacterales	28221|Deltaproteobacteria	D	G-rich domain on putative tyrosine kinase	wzc2	-	-	ko:K16554	ko05111,map05111	-	-	-	ko00000,ko00001,ko02000	8.A.3.1	-	-	AAA_31,CbiA,GNVR,ParA,Wzz
k141_2456_1	1410608.JNKX01000007_gene991	1.52e-42	156.0	COG0438@1|root,COG0438@2|Bacteria,4NPNN@976|Bacteroidetes,2FRYN@200643|Bacteroidia,4AVK4@815|Bacteroidaceae	976|Bacteroidetes	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
k141_2456_3	177439.DPPB72	4.73e-19	85.1	COG0707@1|root,COG0707@2|Bacteria,1RJH9@1224|Proteobacteria,432J5@68525|delta/epsilon subdivisions,2WYGF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM Oligosaccharide biosynthesis protein Alg14 like	-	-	-	-	-	-	-	-	-	-	-	-	Alg14
k141_2456_4	1144305.PMI02_02614	1.55e-31	117.0	COG5017@1|root,COG5017@2|Bacteria,1MZGV@1224|Proteobacteria,2UBWE@28211|Alphaproteobacteria,2K671@204457|Sphingomonadales	204457|Sphingomonadales	S	Glycosyltransferase family 28 C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tran_28_C
k141_3195_2	1121396.KB893046_gene3301	6.78e-218	615.0	COG2204@1|root,COG2204@2|Bacteria,1MVWX@1224|Proteobacteria,42MIB@68525|delta/epsilon subdivisions,2WJQK@28221|Deltaproteobacteria,2MHU2@213118|Desulfobacterales	28221|Deltaproteobacteria	T	sigma54 specific, transcriptional regulator, Fis family	-	-	-	ko:K02481	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Sigma54_activat
k141_1190_1	999541.bgla_1g00330	6.79e-08	56.6	COG1846@1|root,COG1846@2|Bacteria,1N7BV@1224|Proteobacteria,2VT79@28216|Betaproteobacteria,1K776@119060|Burkholderiaceae	28216|Betaproteobacteria	K	PFAM regulatory protein, MarR	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
k141_2457_1	1167006.UWK_03183	1.4e-36	142.0	COG5000@1|root,COG5000@2|Bacteria,1NU7E@1224|Proteobacteria,42YZ2@68525|delta/epsilon subdivisions,2WTQ1@28221|Deltaproteobacteria,2MPM0@213118|Desulfobacterales	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	2.7.13.3	ko:K02668,ko:K07709	ko02020,map02020	M00499,M00501	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_10,PAS_4,PAS_9,sCache_3_2
k141_1191_1	338963.Pcar_2347	1.1e-16	74.3	COG2033@1|root,COG2033@2|Bacteria,1RHE0@1224|Proteobacteria,42SB9@68525|delta/epsilon subdivisions,2WP2D@28221|Deltaproteobacteria,43UZ0@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	PFAM Desulfoferrodoxin, ferrous iron-binding region	dfx	-	1.15.1.2	ko:K05919	-	-	-	-	ko00000,ko01000	-	-	-	Desulfoferrod_N,Desulfoferrodox
k141_1191_2	96561.Dole_2647	1.92e-103	302.0	COG1592@1|root,COG1592@2|Bacteria,1R9WG@1224|Proteobacteria,42N9V@68525|delta/epsilon subdivisions,2WJWQ@28221|Deltaproteobacteria,2MHUF@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM Rubrerythrin	rbr	GO:0003674,GO:0005488,GO:0005506,GO:0043167,GO:0043169,GO:0046872,GO:0046914	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
k141_1192_1	1033802.SSPSH_002955	1.03e-08	59.3	COG1292@1|root,COG1292@2|Bacteria,1MV0K@1224|Proteobacteria,1RRSQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Belongs to the BCCT transporter (TC 2.A.15) family	-	-	-	-	-	-	-	-	-	-	-	-	BCCT
k141_2459_1	1121447.JONL01000005_gene1516	6.59e-82	260.0	COG1217@1|root,COG1217@2|Bacteria,1MV5Q@1224|Proteobacteria,42M3S@68525|delta/epsilon subdivisions,2WJVZ@28221|Deltaproteobacteria,2M885@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	elongation factor Tu domain 2 protein	typA	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2
k141_208_1	96561.Dole_1980	6.49e-14	71.6	COG0616@1|root,COG0616@2|Bacteria,1MUXE@1224|Proteobacteria,42MNA@68525|delta/epsilon subdivisions,2WK7Z@28221|Deltaproteobacteria,2MIPV@213118|Desulfobacterales	28221|Deltaproteobacteria	OU	signal peptide peptidase SppA	sppA	-	-	ko:K04773	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S49
k141_208_2	1121405.dsmv_1445	1.93e-305	847.0	COG0539@1|root,COG0539@2|Bacteria,1MVAV@1224|Proteobacteria,42M29@68525|delta/epsilon subdivisions,2WJ0X@28221|Deltaproteobacteria,2MI6Q@213118|Desulfobacterales	28221|Deltaproteobacteria	J	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence	rpsA	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
k141_208_3	1160721.RBI_I01041	1.67e-57	188.0	COG0283@1|root,COG0283@2|Bacteria,1V3IA@1239|Firmicutes,24HEF@186801|Clostridia,3WIDU@541000|Ruminococcaceae	186801|Clostridia	F	Belongs to the cytidylate kinase family. Type 1 subfamily	cmk	-	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin
k141_208_4	96561.Dole_1983	2.25e-50	172.0	COG0079@1|root,COG0079@2|Bacteria,1MW7I@1224|Proteobacteria,42NCH@68525|delta/epsilon subdivisions,2WJDR@28221|Deltaproteobacteria,2MIX3@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily	hisC	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
k141_209_1	321846.PS417_05525	5.35e-48	170.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains	atoC	GO:0003674,GO:0003700,GO:0004857,GO:0006355,GO:0008073,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0010967,GO:0019219,GO:0019222,GO:0030234,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0033238,GO:0042979,GO:0043086,GO:0044092,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050790,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0065009,GO:0080090,GO:0098772,GO:0140110,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141	-	ko:K02481,ko:K07714	ko02020,map02020	M00500	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
k141_210_1	1322246.BN4_10429	1.47e-44	162.0	COG0683@1|root,COG0683@2|Bacteria,1MWJ1@1224|Proteobacteria,42QZ1@68525|delta/epsilon subdivisions,2WKYF@28221|Deltaproteobacteria,2MA59@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	PFAM Extracellular ligand-binding receptor	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
k141_2460_1	1348635.BBJY01000001_gene2427	2.32e-78	242.0	COG0725@1|root,COG0725@2|Bacteria,1MVNA@1224|Proteobacteria,1RN71@1236|Gammaproteobacteria,1Y0UF@135623|Vibrionales	135623|Vibrionales	P	Bacterial extracellular solute-binding protein	-	-	-	ko:K02020	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	-	SBP_bac_11
k141_5258_21	1385512.N784_09470	5.93e-41	143.0	COG3880@1|root,COG3880@2|Bacteria,1V6YM@1239|Firmicutes,4HH4R@91061|Bacilli,2YABU@289201|Pontibacillus	91061|Bacilli	S	UvrB/uvrC motif	mcsA	GO:0003674,GO:0005488,GO:0005507,GO:0006950,GO:0008150,GO:0008270,GO:0010035,GO:0010038,GO:0042221,GO:0043167,GO:0043169,GO:0046686,GO:0046688,GO:0046870,GO:0046872,GO:0046914,GO:0050896,GO:0050897,GO:0097501,GO:1990169,GO:1990170	-	ko:K19411	-	-	-	-	ko00000	-	-	-	UVR
k141_5258_22	1033737.CAEV01000065_gene2779	5.81e-47	157.0	COG4463@1|root,COG4463@2|Bacteria,1VAXT@1239|Firmicutes,24JH3@186801|Clostridia,36JKR@31979|Clostridiaceae	186801|Clostridia	K	Belongs to the CtsR family	ctsR	-	-	ko:K03708	-	-	-	-	ko00000,ko03000	-	-	-	CtsR
k141_5258_23	272562.CA_C0250	2.54e-56	210.0	COG0840@1|root,COG0840@2|Bacteria,1TP5A@1239|Firmicutes,247S3@186801|Clostridia,36EQK@31979|Clostridiaceae	186801|Clostridia	NT	chemotaxis	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal,dCache_1
k141_4323_1	316067.Geob_3115	9.33e-30	113.0	COG2095@1|root,COG2095@2|Bacteria,1N689@1224|Proteobacteria,42UPI@68525|delta/epsilon subdivisions,2WNQP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	U	UPF0056 inner membrane protein	-	-	-	ko:K05595	-	-	-	-	ko00000,ko02000	2.A.95.1	-	-	MarC
k141_4017_1	357804.Ping_1590	6.83e-21	87.4	2DBXF@1|root,2ZBPB@2|Bacteria,1R36G@1224|Proteobacteria,1T63W@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	CRISPR-associated protein Cas5	ygcI	GO:0002252,GO:0002376,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0006950,GO:0006952,GO:0008150,GO:0009605,GO:0009607,GO:0009615,GO:0043207,GO:0050896,GO:0051607,GO:0051704,GO:0051707,GO:0071667,GO:0097159,GO:0098542,GO:1901363	-	ko:K19125	-	-	-	-	ko00000,ko02048	-	-	-	Cas_Cas5d
k141_4017_2	298386.PBPRC0037	2.26e-189	532.0	COG1857@1|root,COG1857@2|Bacteria,1MVNH@1224|Proteobacteria,1RMBZ@1236|Gammaproteobacteria,1XY5A@135623|Vibrionales	135623|Vibrionales	L	CT1975-like protein	-	-	-	ko:K19124	-	-	-	-	ko00000,ko02048	-	-	-	Cas_CT1975
k141_4017_3	298386.PBPRC0038	2.04e-61	192.0	2D8X9@1|root,31PGX@2|Bacteria,1QM6N@1224|Proteobacteria,1TJEM@1236|Gammaproteobacteria,1Y14B@135623|Vibrionales	135623|Vibrionales	S	defense response to virus	-	-	-	ko:K19046	-	-	-	-	ko00000,ko02048	-	-	-	-
k141_4017_4	357804.Ping_1587	1.92e-32	117.0	2DMIY@1|root,32RWI@2|Bacteria,1RGHV@1224|Proteobacteria,1S1ZF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	crispr-associated protein	ygcH	GO:0002252,GO:0002376,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0006950,GO:0006952,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009615,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0043170,GO:0043207,GO:0044237,GO:0044238,GO:0046483,GO:0050896,GO:0051607,GO:0051704,GO:0051707,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0098542,GO:0140098,GO:1901360,GO:1901363	-	ko:K19126	-	-	-	-	ko00000,ko02048	-	-	-	CRISPR_assoc
k141_912_1	177437.HRM2_00600	1.62e-197	559.0	COG2233@1|root,COG2233@2|Bacteria,1PM6I@1224|Proteobacteria,42NWY@68525|delta/epsilon subdivisions,2WK5Y@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	Permease family	-	-	-	-	-	-	-	-	-	-	-	-	Xan_ur_permease
k141_3283_2	945550.VISI1226_11389	2.52e-184	522.0	COG1344@1|root,COG1344@2|Bacteria,1MV1N@1224|Proteobacteria,1RN0Y@1236|Gammaproteobacteria,1XTVF@135623|Vibrionales	135623|Vibrionales	N	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella	flaE	GO:0005575,GO:0005576,GO:0005623,GO:0009288,GO:0042995,GO:0043226,GO:0043228,GO:0044464	-	ko:K02406	ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flagellin_C,Flagellin_IN,Flagellin_N
k141_3283_3	243277.VC_2145	2.21e-54	178.0	COG2837@1|root,COG2837@2|Bacteria,1MWDD@1224|Proteobacteria,1RMZJ@1236|Gammaproteobacteria,1XU5E@135623|Vibrionales	135623|Vibrionales	P	iron-dependent peroxidase	-	-	-	ko:K07223	-	-	-	-	ko00000	-	-	-	Dyp_perox
k141_2603_1	1121405.dsmv_2856	3.3e-177	520.0	COG3039@1|root,COG3039@2|Bacteria,1PKUP@1224|Proteobacteria,43ECD@68525|delta/epsilon subdivisions,2X0BQ@28221|Deltaproteobacteria,2MP4F@213118|Desulfobacterales	28221|Deltaproteobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_1309_1	1515746.HR45_08665	1.17e-85	266.0	COG2199@1|root,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,1RMA9@1236|Gammaproteobacteria,2QBBH@267890|Shewanellaceae	1236|Gammaproteobacteria	T	response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Response_reg
k141_3284_1	946235.CAER01000060_gene3278	1.52e-06	51.2	COG3829@1|root,COG3829@2|Bacteria,1TP0E@1239|Firmicutes,4HADT@91061|Bacilli,23IWI@182709|Oceanobacillus	91061|Bacilli	KT	Sigma-54 interaction domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,HTH_8,PAS,Sigma54_activat
k141_5260_1	1304885.AUEY01000032_gene1991	2.62e-128	385.0	COG1578@1|root,COG1578@2|Bacteria,1R50K@1224|Proteobacteria,42Q0S@68525|delta/epsilon subdivisions,2WJ5M@28221|Deltaproteobacteria,2MIQ5@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Protein of unknown function DUF89	-	-	-	-	-	-	-	-	-	-	-	-	DUF89
k141_2917_1	672.VV93_v1c03420	2.43e-107	324.0	COG1236@1|root,COG1236@2|Bacteria,1MUDD@1224|Proteobacteria,1RPZC@1236|Gammaproteobacteria,1XUP7@135623|Vibrionales	135623|Vibrionales	J	exonuclease of the beta-lactamase fold involved in RNA processing	-	-	-	ko:K07576	-	-	-	-	ko00000	-	-	-	Beta-Casp,Lactamase_B,RMMBL
k141_2917_2	357804.Ping_0760	1e-45	152.0	COG1669@1|root,COG1669@2|Bacteria,1QYEX@1224|Proteobacteria,1T3PM@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Nucleotidyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_2
k141_2917_3	357804.Ping_0761	2.31e-63	197.0	COG2445@1|root,COG2445@2|Bacteria,1RJB6@1224|Proteobacteria,1S7H3@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function DUF86	-	-	-	-	-	-	-	-	-	-	-	-	DUF86
k141_2917_4	1205908.AKXW01000021_gene983	5.61e-72	218.0	COG0138@1|root,COG0138@2|Bacteria,1QUXG@1224|Proteobacteria,1T24X@1236|Gammaproteobacteria,1XY9V@135623|Vibrionales	135623|Vibrionales	F	Nucleotidyltransferase substrate binding protein like	-	-	-	-	-	-	-	-	-	-	-	-	NTase_sub_bind
k141_2917_5	29495.EA26_02165	2.7e-26	100.0	COG1669@1|root,COG1669@2|Bacteria	2|Bacteria	S	nucleotidyltransferase activity	-	-	3.4.11.5	ko:K01259	ko00330,map00330	-	R00135	-	ko00000,ko00001,ko01000,ko01002	-	-	-	NTP_transf_2
k141_2917_6	675814.VIC_004981	1.39e-114	331.0	COG1573@1|root,COG1573@2|Bacteria,1R9XV@1224|Proteobacteria,1S20R@1236|Gammaproteobacteria,1XVHC@135623|Vibrionales	135623|Vibrionales	L	COG1573 Uracil-DNA glycosylase	-	-	-	-	-	-	-	-	-	-	-	-	UDG
k141_2917_7	1188252.AJYK01000120_gene896	2.23e-106	319.0	COG0111@1|root,COG0111@2|Bacteria,1MW1U@1224|Proteobacteria,1RRQE@1236|Gammaproteobacteria,1XT3B@135623|Vibrionales	135623|Vibrionales	EH	COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases	-	-	-	-	-	-	-	-	-	-	-	-	2-Hacid_dh_C
k141_2917_8	243277.VC_0268	2.52e-107	313.0	COG3068@1|root,COG3068@2|Bacteria,1MWSN@1224|Proteobacteria,1RQDG@1236|Gammaproteobacteria,1XT50@135623|Vibrionales	135623|Vibrionales	S	protein conserved in bacteria	yjaG	-	-	ko:K09891	-	-	-	-	ko00000	-	-	-	DUF416
k141_2917_9	675814.VIC_004978	2.12e-156	450.0	COG1253@1|root,COG1253@2|Bacteria,1MWT3@1224|Proteobacteria,1RQBC@1236|Gammaproteobacteria,1XT75@135623|Vibrionales	135623|Vibrionales	S	COG1253 Hemolysins and related proteins containing CBS domains	-	-	-	-	-	-	-	-	-	-	-	-	CBS,DUF21
k141_3739_1	1304885.AUEY01000001_gene3289	2.15e-29	111.0	COG0664@1|root,COG0664@2|Bacteria,1NBX3@1224|Proteobacteria,42UGQ@68525|delta/epsilon subdivisions,2WQY8@28221|Deltaproteobacteria,2MKR0@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
k141_3739_2	933262.AXAM01000002_gene545	4.28e-41	152.0	COG1639@1|root,COG1639@2|Bacteria,1RBFE@1224|Proteobacteria,42QRK@68525|delta/epsilon subdivisions,2WMYG@28221|Deltaproteobacteria,2MJHI@213118|Desulfobacterales	28221|Deltaproteobacteria	T	HDOD domain	-	-	-	-	-	-	-	-	-	-	-	-	HDOD,zinc_ribbon_4
k141_3739_3	439235.Dalk_2940	2.5e-35	140.0	COG5002@1|root,COG5002@2|Bacteria,1NA7F@1224|Proteobacteria,42YWH@68525|delta/epsilon subdivisions,2WTS2@28221|Deltaproteobacteria,2MMUT@213118|Desulfobacterales	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
k141_3285_1	111781.Lepto7376_4364	3.01e-58	187.0	COG3153@1|root,COG3153@2|Bacteria,1G5GM@1117|Cyanobacteria,1HBEZ@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM GCN5-related N-acetyltransferase	-	-	-	ko:K03824	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_1,Acetyltransf_7,Acetyltransf_9
k141_2918_1	158190.SpiGrapes_1294	4.83e-61	207.0	COG0446@1|root,COG0607@1|root,COG0446@2|Bacteria,COG0607@2|Bacteria,2J5NQ@203691|Spirochaetes	203691|Spirochaetes	C	pyridine nucleotide-disulphide oxidoreductase dimerisation	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Pyr_redox_dim,Rhodanese
k141_1311_1	1448857.JFAP01000004_gene705	3.02e-73	239.0	COG0591@1|root,COG0591@2|Bacteria,1MYTC@1224|Proteobacteria,42P8Z@68525|delta/epsilon subdivisions,2YN9K@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
k141_913_2	1419583.V466_29855	4.1e-49	169.0	2BMZD@1|root,32GJ9@2|Bacteria,1PI6I@1224|Proteobacteria,1STP7@1236|Gammaproteobacteria,1YU3E@136843|Pseudomonas fluorescens group	1236|Gammaproteobacteria	S	Domain of unknown function (DUF4393)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4393
k141_3740_1	1304885.AUEY01000002_gene295	2.88e-46	161.0	COG0265@1|root,COG0265@2|Bacteria	2|Bacteria	O	serine-type endopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,SIR2_2,Trypsin_2
k141_3740_2	1265505.ATUG01000003_gene128	4.54e-10	60.5	COG3876@1|root,COG3876@2|Bacteria,1MX3S@1224|Proteobacteria,42N6K@68525|delta/epsilon subdivisions,2WKFH@28221|Deltaproteobacteria,2MI37@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF1343)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1343
k141_2355_2	675814.VIC_004799	2.87e-132	378.0	COG0193@1|root,COG0193@2|Bacteria,1MX1P@1224|Proteobacteria,1RPK3@1236|Gammaproteobacteria,1XT46@135623|Vibrionales	135623|Vibrionales	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
k141_5007_1	1121396.KB893063_gene1197	1.95e-158	500.0	COG0642@1|root,COG0642@2|Bacteria,1NXDJ@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,Response_reg,SBP_bac_3
k141_5007_2	243277.VC_1301	1.64e-228	637.0	COG0814@1|root,COG0814@2|Bacteria,1NQFA@1224|Proteobacteria,1RQ8Q@1236|Gammaproteobacteria,1XSJ0@135623|Vibrionales	135623|Vibrionales	E	serine transporter	sdaC	-	-	ko:K03837	-	-	-	-	ko00000,ko02000	2.A.42.2.1	-	-	Trp_Tyr_perm
k141_5007_3	314292.VAS14_10619	3.95e-12	62.4	2EFSX@1|root,339IW@2|Bacteria,1NG97@1224|Proteobacteria,1SGWE@1236|Gammaproteobacteria,1XZD8@135623|Vibrionales	135623|Vibrionales	S	Protein of unknown function (DUF2986)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2986
k141_5007_4	870967.VIS19158_19727	7.25e-117	341.0	COG1028@1|root,COG1028@2|Bacteria,1MWBC@1224|Proteobacteria,1RNNV@1236|Gammaproteobacteria,1XSBP@135623|Vibrionales	135623|Vibrionales	IQ	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	yciK	-	-	-	-	-	-	-	-	-	-	-	adh_short
k141_5007_5	1348635.BBJY01000007_gene83	3.2e-180	510.0	COG0616@1|root,COG0616@2|Bacteria,1MUXE@1224|Proteobacteria,1RNN9@1236|Gammaproteobacteria,1XTZB@135623|Vibrionales	135623|Vibrionales	OU	COG0616 Periplasmic serine proteases (ClpP class)	sohB	-	-	ko:K04774	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S49,Peptidase_S49_N
k141_5007_6	796620.VIBC2010_18179	1.56e-49	166.0	COG0705@1|root,COG0705@2|Bacteria,1N8NS@1224|Proteobacteria,1SD4M@1236|Gammaproteobacteria,1XXEV@135623|Vibrionales	135623|Vibrionales	S	membrane protein (homolog of Drosophila rhomboid)	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
k141_5007_7	945543.VIBR0546_04232	5.98e-90	269.0	COG3148@1|root,COG3148@2|Bacteria,1MZCN@1224|Proteobacteria,1S977@1236|Gammaproteobacteria,1XUVF@135623|Vibrionales	135623|Vibrionales	S	DTW	-	-	-	-	-	-	-	-	-	-	-	-	DTW
k141_5007_8	319224.Sputcn32_3188	1.5e-145	418.0	COG0657@1|root,COG0657@2|Bacteria,1NEXK@1224|Proteobacteria,1RNNH@1236|Gammaproteobacteria,2QATS@267890|Shewanellaceae	1236|Gammaproteobacteria	I	PFAM Alpha beta hydrolase fold-3 domain protein	aes	-	-	ko:K01066	-	-	-	-	ko00000,ko01000	-	-	-	Abhydrolase_3
k141_5007_9	1187848.AJYQ01000047_gene651	2.7e-14	71.2	COG3547@1|root,COG3547@2|Bacteria,1MUER@1224|Proteobacteria,1RMAQ@1236|Gammaproteobacteria,1XVPF@135623|Vibrionales	135623|Vibrionales	L	COG3547 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k141_5007_10	326297.Sama_1353	3.2e-209	582.0	28HW8@1|root,2Z82A@2|Bacteria,1R856@1224|Proteobacteria,1S1QX@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_5007_11	558884.JRGM01000140_gene734	4.42e-12	63.9	2FHAI@1|root,3494S@2|Bacteria,1P2ZM@1224|Proteobacteria,1SSTC@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_5007_13	675816.VIA_002725	8.87e-85	254.0	COG1670@1|root,COG1670@2|Bacteria,1QJM4@1224|Proteobacteria,1SNS7@1236|Gammaproteobacteria,1XWRC@135623|Vibrionales	135623|Vibrionales	J	COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
k141_1313_1	177439.DP0282	5.63e-40	157.0	COG1197@1|root,COG1197@2|Bacteria,1MUXG@1224|Proteobacteria,42N8X@68525|delta/epsilon subdivisions,2WIVR@28221|Deltaproteobacteria,2MI3P@213118|Desulfobacterales	28221|Deltaproteobacteria	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
k141_651_1	760154.Sulba_1369	4.92e-125	419.0	COG3210@1|root,COG3210@2|Bacteria,1MX2K@1224|Proteobacteria,42MHY@68525|delta/epsilon subdivisions,2YNDP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	U	domain protein	-	-	-	ko:K15125	ko05133,map05133	-	-	-	ko00000,ko00001,ko00536	-	-	-	Fil_haemagg_2,Haemagg_act
k141_651_3	1151127.KB906326_gene876	1.47e-45	176.0	COG2831@1|root,COG2831@2|Bacteria,1MXF6@1224|Proteobacteria,1RP05@1236|Gammaproteobacteria,1YNJE@136843|Pseudomonas fluorescens group	1236|Gammaproteobacteria	U	Hemolysin	shlB	-	-	ko:K07326	ko05133,map05133	-	-	-	ko00000,ko00001	-	-	-	POTRA_2,POTRA_3,ShlB
k141_3741_1	29495.EA26_11555	6.82e-88	264.0	COG2214@1|root,COG2214@2|Bacteria,1N0S7@1224|Proteobacteria,1SAFR@1236|Gammaproteobacteria,1XTJX@135623|Vibrionales	135623|Vibrionales	O	COG2214 DnaJ-class molecular chaperone	-	-	-	-	-	-	-	-	-	-	-	-	DNAJ_related,DnaJ
k141_3741_2	1238450.VIBNISOn1_660006	4.2e-70	231.0	COG2200@1|root,COG2203@1|root,COG2200@2|Bacteria,COG2203@2|Bacteria,1RGKE@1224|Proteobacteria,1T1I8@1236|Gammaproteobacteria,1XUWZ@135623|Vibrionales	135623|Vibrionales	T	GGDEF family	-	-	3.1.4.52	ko:K20962	ko05111,map05111	-	-	-	ko00000,ko00001,ko01000	-	-	-	EAL,GAF,GAF_2,GGDEF
k141_917_1	1079460.ATTQ01000010_gene75	2.14e-47	161.0	COG1879@1|root,COG1879@2|Bacteria,1NRXG@1224|Proteobacteria,2TT8F@28211|Alphaproteobacteria,4B7NQ@82115|Rhizobiaceae	28211|Alphaproteobacteria	G	ABC-type sugar transport system, periplasmic component	-	-	-	ko:K10552	ko02010,map02010	M00218	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.7	-	-	Peripla_BP_4
k141_3286_1	1121028.ARQE01000001_gene3670	4.48e-102	332.0	COG0643@1|root,COG0643@2|Bacteria,1MUAG@1224|Proteobacteria,2TSN2@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	Histidine kinase	MA20_10410	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt
k141_4018_1	1304885.AUEY01000079_gene1028	1.25e-108	328.0	COG4799@1|root,COG4799@2|Bacteria,1MVAX@1224|Proteobacteria,43AEE@68525|delta/epsilon subdivisions,2WIRF@28221|Deltaproteobacteria,2MIPI@213118|Desulfobacterales	28221|Deltaproteobacteria	I	PFAM carboxyl transferase	-	-	2.1.3.1,2.1.3.15,6.4.1.3	ko:K01966,ko:K17489	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	M00373,M00741	R00353,R01859	RC00040,RC00097,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
k141_4018_3	224324.aq_1614	2.02e-64	231.0	COG0511@1|root,COG5016@1|root,COG0511@2|Bacteria,COG5016@2|Bacteria,2G3RB@200783|Aquificae	200783|Aquificae	C	Oxaloacetate decarboxylase alpha subunit	oadA	-	6.4.1.1	ko:K01960	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	M00173,M00620	R00344	RC00040,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_lipoyl,HMGL-like,PYC_OADA
k141_5032_1	326297.Sama_1877	9.72e-40	136.0	COG2963@1|root,COG2963@2|Bacteria,1MZ5C@1224|Proteobacteria,1S9KN@1236|Gammaproteobacteria,2QCXW@267890|Shewanellaceae	1236|Gammaproteobacteria	L	Transposase	-	-	-	ko:K07483	-	-	-	-	ko00000	-	-	-	HTH_Tnp_1
k141_5032_2	575564.HMPREF0014_00166	7.05e-92	286.0	COG0464@1|root,COG0464@2|Bacteria,1MVVP@1224|Proteobacteria,1RY8X@1236|Gammaproteobacteria,3NPD8@468|Moraxellaceae	1236|Gammaproteobacteria	O	ATPase family associated with various cellular activities (AAA)	-	-	-	-	-	-	-	-	-	-	-	-	AAA
k141_5032_3	754477.Q7C_318	7.54e-150	461.0	COG1404@1|root,COG1404@2|Bacteria,1MVE6@1224|Proteobacteria,1RPCA@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
k141_5032_6	1219065.VPR01S_04_02320	7.4e-259	713.0	COG0582@1|root,COG0582@2|Bacteria,1MU23@1224|Proteobacteria,1RMJ1@1236|Gammaproteobacteria,1XTXF@135623|Vibrionales	135623|Vibrionales	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Arm-DNA-bind_3,Phage_integrase
k141_5032_7	29495.EA26_01800	5.45e-167	471.0	COG1561@1|root,COG1561@2|Bacteria,1MWRA@1224|Proteobacteria,1RMAB@1236|Gammaproteobacteria,1XSZ4@135623|Vibrionales	135623|Vibrionales	S	stress-induced protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF1732,YicC_N
k141_5032_8	1219065.VPR01S_04_02300	9.65e-141	400.0	COG0689@1|root,COG0689@2|Bacteria,1MVFZ@1224|Proteobacteria,1RNTB@1236|Gammaproteobacteria,1XU74@135623|Vibrionales	135623|Vibrionales	J	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates	rph	GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0006139,GO:0006396,GO:0006399,GO:0006401,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016075,GO:0016787,GO:0016788,GO:0019439,GO:0034470,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360,GO:1901361,GO:1901575	2.7.7.56	ko:K00989	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RNase_PH,RNase_PH_C
k141_5032_9	1348635.BBJY01000016_gene4044	5.81e-139	394.0	COG0461@1|root,COG0461@2|Bacteria,1MW6F@1224|Proteobacteria,1RQYG@1236|Gammaproteobacteria,1XT4F@135623|Vibrionales	135623|Vibrionales	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	pyrE	GO:0003674,GO:0003824,GO:0004588,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran
k141_5032_10	945543.VIBR0546_16266	9.49e-202	562.0	COG1560@1|root,COG1560@2|Bacteria,1N9ZJ@1224|Proteobacteria,1RRI7@1236|Gammaproteobacteria,1XTMN@135623|Vibrionales	135623|Vibrionales	M	Catalyzes the transfer of myristate from myristoyl-acyl carrier protein (ACP) to Kdo(2)-(lauroyl)-lipid IV(A) to form Kdo(2)-lipid A	lpxM	-	2.3.1.243	ko:K02560	ko00540,ko01100,map00540,map01100	M00060	R05075	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Lip_A_acyltrans
k141_5032_11	243277.VC_0213	1.82e-182	513.0	COG1560@1|root,COG1560@2|Bacteria,1MVNI@1224|Proteobacteria,1RMZ5@1236|Gammaproteobacteria,1XSK3@135623|Vibrionales	135623|Vibrionales	M	Catalyzes the transfer of laurate from lauroyl-acyl carrier protein (ACP) to Kdo(2)-lipid IV(A) to form Kdo(2)- (lauroyl)-lipid IV(A)	lpxL	-	2.3.1.241	ko:K02517	ko00540,ko01100,map00540,map01100	M00060	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Lip_A_acyltrans
k141_5032_12	675813.VIB_002952	2.56e-115	333.0	COG1309@1|root,COG1309@2|Bacteria,1MWF7@1224|Proteobacteria,1RPZ6@1236|Gammaproteobacteria,1XTMS@135623|Vibrionales	135623|Vibrionales	D	Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions	slmA	GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0043565,GO:0044212,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:1990837,GO:2000112,GO:2001141	-	ko:K05501	-	-	-	-	ko00000,ko03000,ko03036	-	-	-	TetR_N
k141_5032_13	223926.28805163	1.25e-207	583.0	COG0452@1|root,COG0452@2|Bacteria,1MVQP@1224|Proteobacteria,1RMKQ@1236|Gammaproteobacteria,1XT15@135623|Vibrionales	135623|Vibrionales	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	coaBC	-	4.1.1.36,6.3.2.5	ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
k141_5032_14	1219077.VAZ01S_022_00280	1.01e-118	344.0	COG2003@1|root,COG2003@2|Bacteria,1MXZ5@1224|Proteobacteria,1RP86@1236|Gammaproteobacteria,1XTU6@135623|Vibrionales	135623|Vibrionales	E	Belongs to the UPF0758 family	radC	GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360	-	ko:K03630	-	-	-	-	ko00000	-	-	-	RadC
k141_5282_1	1219076.N646_2050	1.8e-34	128.0	COG2177@1|root,COG2177@2|Bacteria,1MU65@1224|Proteobacteria,1RYBV@1236|Gammaproteobacteria,1XUCE@135623|Vibrionales	135623|Vibrionales	D	Part of the ABC transporter FtsEX involved in cellular division	ftsX	-	-	ko:K09811	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	FtsX
k141_5282_3	945543.VIBR0546_16071	5.67e-203	573.0	COG0552@1|root,COG0552@2|Bacteria,1MUDU@1224|Proteobacteria,1RNIN@1236|Gammaproteobacteria,1XUBA@135623|Vibrionales	135623|Vibrionales	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components	ftsY	-	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
k141_5282_4	1219076.N646_2053	2.33e-92	275.0	COG0742@1|root,COG0742@2|Bacteria,1MXKW@1224|Proteobacteria,1RN21@1236|Gammaproteobacteria,1XTTV@135623|Vibrionales	135623|Vibrionales	J	Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle	rsmD	-	2.1.1.171	ko:K08316	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Cons_hypoth95
k141_1331_1	491952.Mar181_2493	6.19e-63	196.0	COG3516@1|root,COG3516@2|Bacteria,1RBNB@1224|Proteobacteria,1S2BT@1236|Gammaproteobacteria,1XK95@135619|Oceanospirillales	135619|Oceanospirillales	S	uncharacterised conserved protein UCP028301	-	-	-	ko:K11901	ko02025,map02025	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	T6SS_VipA
k141_1331_3	675806.VII_000141	1.6e-33	118.0	COG4104@1|root,COG4104@2|Bacteria,1N8V2@1224|Proteobacteria,1SHUF@1236|Gammaproteobacteria,1XYP8@135623|Vibrionales	135623|Vibrionales	S	PAAR repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	PAAR_motif
k141_1331_4	882.DVU_2799	2.88e-35	125.0	COG1846@1|root,COG1846@2|Bacteria,1N244@1224|Proteobacteria,42TYY@68525|delta/epsilon subdivisions,2WQP5@28221|Deltaproteobacteria,2MBZY@213115|Desulfovibrionales	28221|Deltaproteobacteria	K	Transcriptional regulator, marR	-	-	-	-	-	-	-	-	-	-	-	-	MarR
k141_1331_5	575788.VS_1638	3.99e-103	311.0	COG1230@1|root,COG1230@2|Bacteria,1MVQB@1224|Proteobacteria,1RMR8@1236|Gammaproteobacteria,1XSH2@135623|Vibrionales	135623|Vibrionales	P	Cation efflux family	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux
k141_2944_1	1121396.KB893101_gene570	1.13e-90	296.0	COG0643@1|root,COG2198@1|root,COG0643@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,42M6Q@68525|delta/epsilon subdivisions,2WJ5U@28221|Deltaproteobacteria,2MIXJ@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Signal transducing histidine kinase, homodimeric	-	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt,Response_reg
k141_2944_2	879212.DespoDRAFT_02439	2.06e-61	192.0	COG0835@1|root,COG0835@2|Bacteria,1RAH1@1224|Proteobacteria,42SW0@68525|delta/epsilon subdivisions,2WPFF@28221|Deltaproteobacteria,2MK6E@213118|Desulfobacterales	28221|Deltaproteobacteria	NT	Two component signalling adaptor domain	-	-	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
k141_2944_3	933262.AXAM01000090_gene2614	6.48e-105	317.0	COG2201@1|root,COG2201@2|Bacteria,1MWCN@1224|Proteobacteria,42P0R@68525|delta/epsilon subdivisions,2WIKC@28221|Deltaproteobacteria,2MIC3@213118|Desulfobacterales	28221|Deltaproteobacteria	NT	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR	cheB	-	3.1.1.61,3.5.1.44	ko:K03412	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,Response_reg
k141_2041_1	1232437.KL662013_gene1339	1.51e-30	120.0	COG0480@1|root,COG0480@2|Bacteria,1R0V4@1224|Proteobacteria,42M1F@68525|delta/epsilon subdivisions,2WIYM@28221|Deltaproteobacteria,2MHPT@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Elongation factor Tu domain 2	fusA-1	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
k141_2041_2	96561.Dole_1661	4.48e-79	245.0	COG1189@1|root,COG1189@2|Bacteria,1MWP5@1224|Proteobacteria,42R2J@68525|delta/epsilon subdivisions,2WIJ6@28221|Deltaproteobacteria,2MIMF@213118|Desulfobacterales	28221|Deltaproteobacteria	J	PFAM ribosomal RNA methyltransferase RrmJ FtsJ	tlyA	-	2.1.1.226,2.1.1.227	ko:K06442	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ,S4
k141_2041_3	443143.GM18_1116	0.000542	42.4	COG1154@1|root,COG1154@2|Bacteria,1MUSJ@1224|Proteobacteria,42M35@68525|delta/epsilon subdivisions,2WIX5@28221|Deltaproteobacteria,43UFS@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)	dxs	-	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	-	DXP_synthase_N,Transket_pyr,Transketolase_C
k141_1332_1	272562.CA_C3012	5.99e-09	61.2	COG0488@1|root,COG0488@2|Bacteria,1TPAX@1239|Firmicutes,247Q9@186801|Clostridia,36FYC@31979|Clostridiaceae	186801|Clostridia	S	ABC transporter	yfmR	-	-	ko:K15738	-	-	-	-	ko00000,ko02000	3.A.1.120.6	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
k141_5033_1	903818.KI912268_gene1090	7.5e-10	66.6	COG1639@1|root,COG2204@1|root,COG1639@2|Bacteria,COG2204@2|Bacteria	2|Bacteria	T	phosphorelay signal transduction system	phcR	-	-	ko:K19622	ko02020,map02020	-	-	-	ko00000,ko00001,ko02022	-	-	-	HATPase_c,HDOD,Response_reg
k141_5283_1	553175.POREN0001_1288	1.49e-25	106.0	COG1012@1|root,COG1012@2|Bacteria,4NFTW@976|Bacteroidetes,2FQQ7@200643|Bacteroidia,22WBS@171551|Porphyromonadaceae	976|Bacteroidetes	C	1-pyrroline-5-carboxylate dehydrogenase	pruA	-	1.2.1.88,1.5.5.2	ko:K00294,ko:K13821	ko00250,ko00330,ko01100,ko01110,ko01130,map00250,map00330,map01100,map01110,map01130	-	R00245,R00707,R00708,R01253,R04444,R04445,R05051	RC00080,RC00083,RC00216,RC00242,RC00255	ko00000,ko00001,ko01000,ko03000	-	-	-	Aldedh,Pro_dh
k141_5283_2	1265505.ATUG01000001_gene4766	1.02e-50	173.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,42N0C@68525|delta/epsilon subdivisions,2WIUM@28221|Deltaproteobacteria,2MI28@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Aldehyde dehydrogenase family	-	-	1.2.1.3	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
k141_5034_1	244581.IM40_01135	1.68e-38	139.0	COG4239@1|root,COG4239@2|Bacteria,1MUM5@1224|Proteobacteria,2TR1Y@28211|Alphaproteobacteria,47EX2@766|Rickettsiales	766|Rickettsiales	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K13895	ko02010,map02010	M00349	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.21,3.A.1.5.24	-	-	BPD_transp_1,OppC_N
k141_5034_2	1577887.JSYG01000009_gene500	8.7e-88	268.0	COG4174@1|root,COG4174@2|Bacteria,1MVKE@1224|Proteobacteria,1RMH8@1236|Gammaproteobacteria,2JCC1@204037|Dickeya	1236|Gammaproteobacteria	P	PFAM binding-protein-dependent transport systems inner membrane component	yejB	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006857,GO:0008150,GO:0015833,GO:0015893,GO:0016020,GO:0022857,GO:0035672,GO:0042221,GO:0042493,GO:0042884,GO:0042886,GO:0042891,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944	-	ko:K13894	ko02010,map02010	M00349	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.21,3.A.1.5.24	-	-	BPD_transp_1
k141_2386_7	1122194.AUHU01000003_gene2408	1.46e-210	617.0	COG3507@1|root,COG3693@1|root,COG5297@1|root,COG3507@2|Bacteria,COG3693@2|Bacteria,COG5297@2|Bacteria,1R7BZ@1224|Proteobacteria,1S17S@1236|Gammaproteobacteria,466TT@72275|Alteromonadaceae	1236|Gammaproteobacteria	G	Glycosyl hydrolase family 10	-	-	-	-	-	-	-	-	-	-	-	-	CBM_2,CBM_4_9,CBM_6,Glyco_hydro_10,Glyco_hydro_43
k141_2386_8	870967.VIS19158_03996	2.81e-33	116.0	2B58X@1|root,31NS4@2|Bacteria,1QKGA@1224|Proteobacteria,1TIKE@1236|Gammaproteobacteria,1XZA5@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_2386_11	345073.VC395_A0196	4.28e-18	82.4	2AXP9@1|root,31PPT@2|Bacteria,1QMD3@1224|Proteobacteria,1TJMT@1236|Gammaproteobacteria,1Y1EV@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_2386_12	345073.VC395_A0196	4.15e-07	50.8	2AXP9@1|root,31PPT@2|Bacteria,1QMD3@1224|Proteobacteria,1TJMT@1236|Gammaproteobacteria,1Y1EV@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_2386_13	1219077.VAZ01S_018_00120	5.22e-55	173.0	2B76D@1|root,32088@2|Bacteria,1QK7E@1224|Proteobacteria,1TIAN@1236|Gammaproteobacteria,1XYRS@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_2386_14	345073.VC395_A0194	3.97e-21	88.2	2BX0J@1|root,30H36@2|Bacteria,1R6TW@1224|Proteobacteria,1RZIA@1236|Gammaproteobacteria,1XWQD@135623|Vibrionales	135623|Vibrionales	S	Phage regulatory protein CII (CP76)	-	-	-	-	-	-	-	-	-	-	-	-	Phage_CP76
k141_2386_16	316275.VSAL_I1010	1.34e-66	214.0	COG2932@1|root,COG2932@2|Bacteria,1NDB9@1224|Proteobacteria,1RNJS@1236|Gammaproteobacteria,1XXPH@135623|Vibrionales	135623|Vibrionales	K	Bacteriophage CI repressor C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Phage_CI_C,Phage_CI_repr
k141_2386_20	1191299.AJYX01000126_gene1029	1.31e-35	130.0	COG0582@1|root,COG0582@2|Bacteria,1N45B@1224|Proteobacteria,1RNDM@1236|Gammaproteobacteria,1XUBJ@135623|Vibrionales	135623|Vibrionales	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
k141_2386_21	70734.Q9T205_9CAUD	2.35e-59	195.0	4QAQE@10239|Viruses,4QUYF@35237|dsDNA viruses  no RNA stage,4QPDM@28883|Caudovirales,4QI35@10662|Myoviridae	10662|Myoviridae	S	DNA integration	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_2386_22	675812.VHA_002542	1.46e-24	99.0	COG2801@1|root,COG2801@2|Bacteria,1MVN5@1224|Proteobacteria,1RP6D@1236|Gammaproteobacteria,1XYIX@135623|Vibrionales	135623|Vibrionales	L	Integrase core domain	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	rve,rve_3
k141_2386_23	55601.VANGNB10_cI1986c	1.62e-202	568.0	COG1344@1|root,COG1344@2|Bacteria,1MV1N@1224|Proteobacteria,1RN0Y@1236|Gammaproteobacteria,1XSDK@135623|Vibrionales	135623|Vibrionales	N	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella	flaA	GO:0005575,GO:0005576,GO:0005623,GO:0009288,GO:0042995,GO:0043226,GO:0043228,GO:0044464	-	ko:K02406	ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flagellin_C,Flagellin_IN,Flagellin_N
k141_2386_24	55601.VANGNB10_cI1987c	1.4e-205	578.0	COG1344@1|root,COG1344@2|Bacteria,1PJUJ@1224|Proteobacteria,1RPNR@1236|Gammaproteobacteria,1XTKN@135623|Vibrionales	135623|Vibrionales	N	COG1344 Flagellin and related hook-associated proteins	flgL	-	-	ko:K02397	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flagellin_C,Flagellin_N
k141_2386_25	1348635.BBJY01000002_gene3374	0.0	881.0	COG1256@1|root,COG1256@2|Bacteria,1MV2M@1224|Proteobacteria,1RMEA@1236|Gammaproteobacteria,1XU4C@135623|Vibrionales	135623|Vibrionales	N	flagellar hook-associated protein	flgK	-	-	ko:K02396	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod,Flg_bbr_C
k141_2386_26	1348635.BBJY01000002_gene3375	1.71e-122	361.0	COG1705@1|root,COG3951@1|root,COG1705@2|Bacteria,COG3951@2|Bacteria,1MX2W@1224|Proteobacteria,1RPGY@1236|Gammaproteobacteria,1XSX3@135623|Vibrionales	135623|Vibrionales	N	Flagellar rod assembly protein muramidase FlgJ	flgJ	GO:0003674,GO:0005198	-	ko:K02395	-	-	-	-	ko00000,ko02035	-	-	-	Glucosaminidase,Rod-binding
k141_2386_27	1187848.AJYQ01000102_gene1018	1.69e-207	580.0	COG1706@1|root,COG1706@2|Bacteria,1MVKW@1224|Proteobacteria,1RMRB@1236|Gammaproteobacteria,1XTSD@135623|Vibrionales	135623|Vibrionales	N	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation	flgI	GO:0003674,GO:0005198,GO:0005575,GO:0005623,GO:0009288,GO:0009425,GO:0042995,GO:0043226,GO:0043228,GO:0044422,GO:0044461,GO:0044463,GO:0044464	-	ko:K02394	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FlgI
k141_2386_28	243277.VC_2194	7.95e-137	392.0	COG2063@1|root,COG2063@2|Bacteria,1RDEY@1224|Proteobacteria,1S3XK@1236|Gammaproteobacteria,1XUAA@135623|Vibrionales	135623|Vibrionales	N	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation	flgH	GO:0003674,GO:0005198,GO:0005575,GO:0005623,GO:0009288,GO:0009425,GO:0042995,GO:0043226,GO:0043228,GO:0044422,GO:0044461,GO:0044463,GO:0044464	-	ko:K02393	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FlgH
k141_2386_29	1348635.BBJY01000002_gene3378	2.51e-166	467.0	COG4786@1|root,COG4786@2|Bacteria,1MVMA@1224|Proteobacteria,1RMJ2@1236|Gammaproteobacteria,1XU20@135623|Vibrionales	135623|Vibrionales	N	Belongs to the flagella basal body rod proteins family	flgG	-	-	ko:K02392	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod,Flg_bbr_C
k141_2386_30	675813.VIB_000722	1.41e-145	414.0	COG4787@1|root,COG4787@2|Bacteria,1NZWQ@1224|Proteobacteria,1RNVX@1236|Gammaproteobacteria,1XTW3@135623|Vibrionales	135623|Vibrionales	N	Belongs to the flagella basal body rod proteins family	flgF	-	-	ko:K02391	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod,Flg_bbr_C
k141_2386_31	1348635.BBJY01000002_gene3380	1.67e-276	760.0	COG1749@1|root,COG1749@2|Bacteria,1MU5J@1224|Proteobacteria,1RMWX@1236|Gammaproteobacteria,1XU4Y@135623|Vibrionales	135623|Vibrionales	N	Flagellar hook protein FlgE	flgE	-	-	ko:K02390	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FlaE,Flg_bb_rod,Flg_bbr_C
k141_2386_32	1219065.VPR01S_10_00130	1.73e-128	369.0	COG1843@1|root,COG1843@2|Bacteria,1MXCG@1224|Proteobacteria,1RPZI@1236|Gammaproteobacteria,1XTM4@135623|Vibrionales	135623|Vibrionales	N	Required for flagellar hook formation. May act as a scaffolding protein	flgD	-	-	ko:K02389	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FLgD_tudor,FlgD,FlgD_ig
k141_2386_33	945550.VISI1226_05426	7.13e-76	228.0	COG1558@1|root,COG1558@2|Bacteria,1RHI3@1224|Proteobacteria,1S653@1236|Gammaproteobacteria,1XWW3@135623|Vibrionales	135623|Vibrionales	N	Belongs to the flagella basal body rod proteins family	flgC	-	-	ko:K02388	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod,Flg_bbr_C
k141_2386_34	29495.EA26_04700	3.33e-73	221.0	COG1815@1|root,COG1815@2|Bacteria,1MZ8P@1224|Proteobacteria,1S9DS@1236|Gammaproteobacteria,1XWV7@135623|Vibrionales	135623|Vibrionales	N	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body	flgB	-	-	ko:K02387	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod
k141_2386_35	675815.VOA_002540	1.43e-167	471.0	COG1352@1|root,COG1352@2|Bacteria,1MU6W@1224|Proteobacteria,1RMFK@1236|Gammaproteobacteria,1XSQ2@135623|Vibrionales	135623|Vibrionales	NT	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP	cheR	GO:0006935,GO:0008150,GO:0009605,GO:0040011,GO:0042221,GO:0042330,GO:0050896	2.1.1.80	ko:K00575	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheR,CheR_N
k141_2386_36	1219065.VPR01S_10_00170	6.53e-174	490.0	COG0784@1|root,COG0835@1|root,COG0784@2|Bacteria,COG0835@2|Bacteria,1N81M@1224|Proteobacteria,1RPS1@1236|Gammaproteobacteria,1XSWX@135623|Vibrionales	135623|Vibrionales	T	COG0835 Chemotaxis signal transduction protein	cheV	-	-	ko:K03415	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	CheW,Response_reg
k141_2386_37	675815.VOA_002542	3.85e-92	278.0	COG1261@1|root,COG1261@2|Bacteria,1N1SA@1224|Proteobacteria,1S8SQ@1236|Gammaproteobacteria,1XSM2@135623|Vibrionales	135623|Vibrionales	N	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly	flgA	-	-	ko:K02386	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	ChapFlgA
k141_2386_38	243277.VC_2204	1.71e-27	103.0	COG2747@1|root,COG2747@2|Bacteria,1NGJA@1224|Proteobacteria,1SGQ4@1236|Gammaproteobacteria,1XYEH@135623|Vibrionales	135623|Vibrionales	N	COG2747 Negative regulator of flagellin synthesis (anti-sigma28 factor)	flgM	-	-	ko:K02398	ko02020,ko02025,ko02026,ko02040,map02020,map02025,map02026,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FlgM
k141_2386_39	675815.VOA_002544	2.29e-50	164.0	COG3418@1|root,33AIS@2|Bacteria,1NH78@1224|Proteobacteria,1SGPM@1236|Gammaproteobacteria,1XXGG@135623|Vibrionales	135623|Vibrionales	NOU	FlgN protein	flgN	-	-	ko:K02399	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FlgN
k141_2386_40	675806.VII_001629	7.54e-67	206.0	COG3018@1|root,COG3018@2|Bacteria,1RGG9@1224|Proteobacteria,1T0JR@1236|Gammaproteobacteria,1Y2ZP@135623|Vibrionales	135623|Vibrionales	N	protein conserved in bacteria	-	-	-	ko:K09860	-	-	-	-	ko00000	-	-	-	LPP20
k141_2386_41	675806.VII_001628	4.58e-130	371.0	COG5616@1|root,COG5616@2|Bacteria,1R4DP@1224|Proteobacteria,1SAIF@1236|Gammaproteobacteria,1XTPR@135623|Vibrionales	135623|Vibrionales	S	Integral membrane protein	VC2207	-	-	-	-	-	-	-	-	-	-	-	-
k141_2386_42	55601.VANGNB10_cI2005	5.37e-181	514.0	28KVI@1|root,2ZAC4@2|Bacteria,1RBAQ@1224|Proteobacteria,1S3C3@1236|Gammaproteobacteria,1XV1Z@135623|Vibrionales	135623|Vibrionales	N	Flagellar assembly protein T, C-terminal domain	flgT	-	-	-	-	-	-	-	-	-	-	-	FlgT_C,FlgT_M,FlgT_N
k141_2386_44	1348635.BBJY01000038_gene8	2.52e-72	218.0	COG0599@1|root,COG0599@2|Bacteria,1RH7V@1224|Proteobacteria,1S6K3@1236|Gammaproteobacteria,1XXKP@135623|Vibrionales	135623|Vibrionales	S	Carboxymuconolactone decarboxylase family	-	-	4.1.1.44	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	-	R03470	RC00938	ko00000,ko00001,ko01000	-	-	-	CMD
k141_2386_45	223926.28809510	5.16e-57	179.0	COG0789@1|root,COG0789@2|Bacteria,1N9C6@1224|Proteobacteria,1SAI3@1236|Gammaproteobacteria,1XXVP@135623|Vibrionales	135623|Vibrionales	K	helix_turn_helix, mercury resistance	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
k141_2386_46	595494.Tola_1892	7.36e-177	503.0	COG0371@1|root,COG0371@2|Bacteria,1MWAE@1224|Proteobacteria,1RN9F@1236|Gammaproteobacteria,1Y5GQ@135624|Aeromonadales	135624|Aeromonadales	C	Iron-containing alcohol dehydrogenase	gldA	-	1.1.1.6	ko:K00005	ko00561,ko00640,ko01100,map00561,map00640,map01100	-	R01034,R10715,R10717	RC00029,RC00117,RC00670	ko00000,ko00001,ko01000	-	-	-	Fe-ADH
k141_2386_47	1238450.VIBNISOn1_1750032	6.65e-24	110.0	COG2931@1|root,2ZQV3@2|Bacteria,1P9CB@1224|Proteobacteria	1224|Proteobacteria	Q	RTX toxins and related Ca2 -binding	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_2386_48	633.DJ40_1761	1.17e-133	399.0	COG0477@1|root,COG0477@2|Bacteria,1MU46@1224|Proteobacteria,1RMJI@1236|Gammaproteobacteria,41F6T@629|Yersinia	1236|Gammaproteobacteria	EGP	Sugar (and other) transporter	proP_1	-	-	ko:K03762	-	-	-	-	ko00000,ko02000	2.A.1.6.4	-	-	MFS_1
k141_4441_1	177437.HRM2_41800	7e-108	329.0	2DBU2@1|root,2ZB3S@2|Bacteria,1N1MT@1224|Proteobacteria,42VJX@68525|delta/epsilon subdivisions,2WSPP@28221|Deltaproteobacteria,2MNKM@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_4
k141_4441_2	909663.KI867150_gene1010	1.36e-12	69.7	2DBU2@1|root,2ZB3S@2|Bacteria,1N1MT@1224|Proteobacteria,42VJX@68525|delta/epsilon subdivisions,2WSPP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_4
k141_386_1	1123508.JH636441_gene3386	8.68e-25	118.0	COG2931@1|root,COG3210@1|root,COG4625@1|root,COG2931@2|Bacteria,COG3210@2|Bacteria,COG4625@2|Bacteria	2|Bacteria	T	pathogenesis	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,DUF4347,MAM,Trypsin_2
k141_3420_1	1190603.AJYD01000015_gene1045	7.46e-70	239.0	COG1388@1|root,COG1388@2|Bacteria,1P36H@1224|Proteobacteria,1SSMK@1236|Gammaproteobacteria,1XWQZ@135623|Vibrionales	135623|Vibrionales	M	Lysin motif	-	-	-	-	-	-	-	-	-	-	-	-	LysM
k141_3420_2	1280001.BAOA01000100_gene4462	1.73e-123	364.0	COG1262@1|root,COG1262@2|Bacteria,1PDSD@1224|Proteobacteria,1S4ZV@1236|Gammaproteobacteria,1XVWH@135623|Vibrionales	135623|Vibrionales	S	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
k141_3087_1	1122134.KB893650_gene1755	1.08e-07	49.3	2DR5Z@1|root,33ABB@2|Bacteria,1NIYJ@1224|Proteobacteria,1SGQ9@1236|Gammaproteobacteria,1XQB9@135619|Oceanospirillales	135619|Oceanospirillales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_3087_2	1238450.VIBNISOn1_480012	2.2e-164	491.0	COG1368@1|root,COG1368@2|Bacteria,1REMM@1224|Proteobacteria,1SZIF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
k141_3087_3	243277.VC_0161	6.21e-157	447.0	COG0583@1|root,COG0583@2|Bacteria,1MZX1@1224|Proteobacteria,1RNFR@1236|Gammaproteobacteria,1XSJR@135623|Vibrionales	135623|Vibrionales	K	Transcriptional regulator	ilvY	-	-	ko:K02521	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,LysR_substrate
k141_3087_4	223926.28805017	0.0	894.0	COG0059@1|root,COG0059@2|Bacteria,1MV7M@1224|Proteobacteria,1RNA8@1236|Gammaproteobacteria,1XSFQ@135623|Vibrionales	135623|Vibrionales	EH	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate	ilvC	GO:0003674,GO:0003824,GO:0004455,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.86	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R03051,R04439,R04440,R05068,R05069,R05071	RC00726,RC00836,RC00837,RC01726	ko00000,ko00001,ko00002,ko01000	-	-	-	IlvC,IlvN
k141_3087_6	223926.28805023	0.0	1155.0	COG0210@1|root,COG0210@2|Bacteria,1MU0G@1224|Proteobacteria,1RNJI@1236|Gammaproteobacteria,1XTFN@135623|Vibrionales	135623|Vibrionales	L	it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction	rep	-	3.6.4.12	ko:K03656	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
k141_3087_7	406817.XNC1_0399	3.52e-09	53.9	28Z00@1|root,2ZKSP@2|Bacteria,1P60B@1224|Proteobacteria,1SVSK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_3087_8	1238450.VIBNISOn1_1200005	0.0	977.0	COG1123@1|root,COG4172@2|Bacteria,1MU09@1224|Proteobacteria,1RMEI@1236|Gammaproteobacteria,1XTGQ@135623|Vibrionales	135623|Vibrionales	P	Belongs to the ABC transporter superfamily	dppD	-	-	ko:K02031,ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
k141_3087_9	1219065.VPR01S_30_00310	5.7e-310	852.0	COG0747@1|root,COG0747@2|Bacteria,1MUZH@1224|Proteobacteria,1RNES@1236|Gammaproteobacteria,1XTQI@135623|Vibrionales	135623|Vibrionales	E	COG0747 ABC-type dipeptide transport system, periplasmic component	dppA	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
k141_3087_10	672.VV93_v1c00400	1.58e-189	531.0	COG0601@1|root,COG0601@2|Bacteria,1MU8Z@1224|Proteobacteria,1RNJ1@1236|Gammaproteobacteria,1XTA1@135623|Vibrionales	135623|Vibrionales	P	COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components	dppB	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
k141_3087_11	870967.VIS19158_21758	7.76e-185	518.0	COG1173@1|root,COG1173@2|Bacteria,1MUG0@1224|Proteobacteria,1RN08@1236|Gammaproteobacteria,1XTS5@135623|Vibrionales	135623|Vibrionales	P	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components	dppC	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
k141_3087_12	1191299.AJYX01000038_gene3328	5.71e-73	234.0	2AVT3@1|root,31MKG@2|Bacteria,1QJEW@1224|Proteobacteria,1THE8@1236|Gammaproteobacteria,1XURJ@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	SPOR
k141_3087_13	1515746.HR45_15320	2.64e-116	344.0	COG1879@1|root,COG1879@2|Bacteria,1MWGU@1224|Proteobacteria,1RQQZ@1236|Gammaproteobacteria,2QD5X@267890|Shewanellaceae	1236|Gammaproteobacteria	G	PFAM periplasmic binding protein LacI transcriptional regulator	-	-	-	ko:K17205	ko02010,map02010	M00591	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.15	-	-	Peripla_BP_4
k141_3087_14	1112217.PPL19_09742	4.8e-76	263.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	NT	chemotaxis, protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal
k141_3087_15	1280949.HAD_17206	9.11e-136	431.0	COG1629@1|root,COG4771@2|Bacteria,1MXAE@1224|Proteobacteria,2TRQV@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	receptor	-	-	-	-	-	-	-	-	-	-	-	-	Plug,STN
k141_3087_16	1370122.JHXQ01000017_gene869	1.36e-167	520.0	COG0612@1|root,COG0612@2|Bacteria,1NAH6@1224|Proteobacteria,2U0S5@28211|Alphaproteobacteria,4BCFI@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Belongs to the peptidase M16 family	pqqL	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
k141_3087_17	1190606.AJYG01000197_gene4235	1.52e-142	413.0	COG1133@1|root,COG1133@2|Bacteria,1QU39@1224|Proteobacteria,1T1PR@1236|Gammaproteobacteria,1XV6E@135623|Vibrionales	135623|Vibrionales	I	SbmA/BacA-like family	-	-	-	ko:K17938	-	-	-	-	ko00000,ko02000	9.A.18.1	-	-	SbmA_BacA
k141_3087_18	226186.BT_0285	1.93e-08	61.6	COG0811@1|root,COG0811@2|Bacteria,4PIHE@976|Bacteroidetes,2FPTA@200643|Bacteroidia,4AQ5U@815|Bacteroidaceae	976|Bacteroidetes	U	MotA/TolQ/ExbB proton channel family	-	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
k141_3087_19	1187848.AJYQ01000156_gene3801	4.66e-12	66.6	COG0848@1|root,COG0848@2|Bacteria,1N85T@1224|Proteobacteria,1SE81@1236|Gammaproteobacteria,1Y2AY@135623|Vibrionales	135623|Vibrionales	U	Biopolymer transport protein ExbD/TolR	-	-	-	-	-	-	-	-	-	-	-	-	ExbD
k141_3421_1	243277.VC_A0802	6.14e-46	170.0	COG1368@1|root,COG1368@2|Bacteria,1MVCM@1224|Proteobacteria,1RNJ3@1236|Gammaproteobacteria,1XVBR@135623|Vibrionales	135623|Vibrionales	M	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
k141_74_2	1232437.KL661978_gene3855	6.18e-101	301.0	COG0805@1|root,COG0805@2|Bacteria,1MVAY@1224|Proteobacteria,42MM7@68525|delta/epsilon subdivisions,2WKJW@28221|Deltaproteobacteria,2MI7G@213118|Desulfobacterales	28221|Deltaproteobacteria	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides	tatC	-	-	ko:K03118	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	TatC
k141_75_1	1265505.ATUG01000001_gene3579	1.18e-66	216.0	COG2206@1|root,COG2206@2|Bacteria,1MW7F@1224|Proteobacteria,42PGR@68525|delta/epsilon subdivisions,2WJ4K@28221|Deltaproteobacteria,2MMND@213118|Desulfobacterales	28221|Deltaproteobacteria	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	HD,HD_5
k141_4777_2	1540257.JQMW01000013_gene1165	5.17e-88	288.0	COG0642@1|root,COG2205@2|Bacteria,1TRAB@1239|Firmicutes,24DV3@186801|Clostridia,36HES@31979|Clostridiaceae	186801|Clostridia	T	Domain of unknown function (DUF4173)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4173
k141_4777_3	1123009.AUID01000030_gene1359	3.57e-223	634.0	COG0659@1|root,COG0659@2|Bacteria,1TPI4@1239|Firmicutes,24978@186801|Clostridia,268H8@186813|unclassified Clostridiales	186801|Clostridia	P	Sulfate permease family	sulP	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
k141_4777_4	1499689.CCNN01000007_gene1058	4.13e-47	164.0	COG0600@1|root,COG0600@2|Bacteria,1V73W@1239|Firmicutes,24A2R@186801|Clostridia,36FJW@31979|Clostridiaceae	186801|Clostridia	P	binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02050	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	ABC_tran,BPD_transp_1
k141_4777_5	1280680.AUJU01000006_gene1143	5.32e-30	125.0	COG0715@1|root,COG0715@2|Bacteria,1TT2F@1239|Firmicutes,249M2@186801|Clostridia,4BWRS@830|Butyrivibrio	186801|Clostridia	P	NMT1/THI5 like	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1,NMT1_2,Phosphonate-bd,VitK2_biosynth
k141_4777_6	293826.Amet_1128	1.11e-67	215.0	COG1116@1|root,COG1116@2|Bacteria,1V7QX@1239|Firmicutes,24H9Z@186801|Clostridia,36EVS@31979|Clostridiaceae	186801|Clostridia	P	ABC transporter	ssuB1	-	-	ko:K02049	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	ABC_tran
k141_4777_8	82654.Pse7367_1252	4.39e-10	72.4	COG0457@1|root,COG0840@1|root,COG5002@1|root,COG0457@2|Bacteria,COG0840@2|Bacteria,COG5002@2|Bacteria,1G0Y4@1117|Cyanobacteria,1HF2F@1150|Oscillatoriales	1117|Cyanobacteria	NT	Methyl-accepting chemotaxis protein	-	-	-	ko:K02660	ko02020,ko02025,map02020,map02025	-	-	-	ko00000,ko00001,ko02035,ko02044	-	-	-	HAMP,MCPsignal,dCache_1
k141_4777_9	1123511.KB905866_gene3785	1.54e-172	534.0	COG1816@1|root,COG1816@2|Bacteria,1UHMY@1239|Firmicutes	1239|Firmicutes	F	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism	-	-	-	-	-	-	-	-	-	-	-	-	A_deaminase
k141_4777_10	768710.DesyoDRAFT_2417	1.67e-30	139.0	COG1131@1|root,COG1131@2|Bacteria	2|Bacteria	V	ATPase activity	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,Pkinase
k141_4777_12	585501.HMPREF6123_2200	1.25e-106	319.0	COG1408@1|root,COG1408@2|Bacteria,1UU17@1239|Firmicutes,248PS@186801|Clostridia	186801|Clostridia	M	Ser Thr phosphatase family protein	-	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	Metallophos
k141_4777_13	198467.NP92_03420	5.64e-20	101.0	COG0840@1|root,COG0840@2|Bacteria,1TP5A@1239|Firmicutes,4H9RZ@91061|Bacilli	91061|Bacilli	NT	chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal,dCache_1,sCache_3_3
k141_4777_14	1123009.AUID01000002_gene2204	2.06e-35	142.0	COG0845@1|root,COG0845@2|Bacteria,1UUEP@1239|Firmicutes,24CTR@186801|Clostridia	186801|Clostridia	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23,OEP
k141_1405_22	96561.Dole_0713	1.37e-47	155.0	COG0091@1|root,COG0091@2|Bacteria,1RH0W@1224|Proteobacteria,42TRE@68525|delta/epsilon subdivisions,2WQBH@28221|Deltaproteobacteria,2MKFE@213118|Desulfobacterales	28221|Deltaproteobacteria	J	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome	rplV	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02890	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L22
k141_1405_23	207559.Dde_2253	1.16e-48	156.0	COG0185@1|root,COG0185@2|Bacteria,1RGYX@1224|Proteobacteria,42THY@68525|delta/epsilon subdivisions,2WQ0F@28221|Deltaproteobacteria,2MBZW@213115|Desulfovibrionales	28221|Deltaproteobacteria	J	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA	rpsS	GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904	-	ko:K02965	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S19
k141_1405_24	1121405.dsmv_3586	1.41e-151	431.0	COG0090@1|root,COG0090@2|Bacteria,1MVTD@1224|Proteobacteria,42MBV@68525|delta/epsilon subdivisions,2WIRE@28221|Deltaproteobacteria,2MIFY@213118|Desulfobacterales	28221|Deltaproteobacteria	J	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity	rplB	GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02886	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L2,Ribosomal_L2_C
k141_1405_25	1304885.AUEY01000001_gene3245	1.7e-31	113.0	COG0089@1|root,COG0089@2|Bacteria,1MZXX@1224|Proteobacteria,42V3Y@68525|delta/epsilon subdivisions,2WRMX@28221|Deltaproteobacteria,2MKJ3@213118|Desulfobacterales	28221|Deltaproteobacteria	J	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome	rplW	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02892	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L23
k141_1405_26	879212.DespoDRAFT_02463	1.15e-33	122.0	COG0088@1|root,COG0088@2|Bacteria,1MXPF@1224|Proteobacteria,42MPW@68525|delta/epsilon subdivisions,2WN96@28221|Deltaproteobacteria,2MJHZ@213118|Desulfobacterales	28221|Deltaproteobacteria	J	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome	rplD	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02926	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L4
k141_3102_1	177437.HRM2_38250	2.42e-127	382.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MIZ@68525|delta/epsilon subdivisions,2WIUX@28221|Deltaproteobacteria,2MJ42@213118|Desulfobacterales	28221|Deltaproteobacteria	T	PFAM ATP-binding region ATPase domain protein	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	CHASE5,HAMP,HATPase_c,HisKA,dCache_1,dCache_2
k141_3102_2	1121456.ATVA01000015_gene2404	1.67e-93	285.0	COG0517@1|root,COG2204@1|root,COG0517@2|Bacteria,COG2204@2|Bacteria,1NMVW@1224|Proteobacteria,42N24@68525|delta/epsilon subdivisions,2WIQ6@28221|Deltaproteobacteria,2M9XV@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	PFAM response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	CBS,Response_reg
k141_3102_3	177437.HRM2_38270	0.0	999.0	COG1055@1|root,COG1055@2|Bacteria,1QUC0@1224|Proteobacteria,43BR6@68525|delta/epsilon subdivisions,2WJVM@28221|Deltaproteobacteria,2MIF3@213118|Desulfobacterales	28221|Deltaproteobacteria	P	PFAM sodium sulfate symporter	-	-	-	-	-	-	-	-	-	-	-	-	Na_sulph_symp
k141_91_1	177437.HRM2_24790	1.69e-86	260.0	COG0009@1|root,COG0009@2|Bacteria,1MVPM@1224|Proteobacteria,42QSV@68525|delta/epsilon subdivisions,2WMZ5@28221|Deltaproteobacteria,2MI25@213118|Desulfobacterales	28221|Deltaproteobacteria	J	TIGRFAM Sua5 YciO YrdC YwlC family protein	yrdC	-	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	Sua5_yciO_yrdC
k141_91_2	1265505.ATUG01000003_gene132	2.32e-37	136.0	COG0616@1|root,COG0616@2|Bacteria,1MUXE@1224|Proteobacteria,42MNA@68525|delta/epsilon subdivisions,2WK7Z@28221|Deltaproteobacteria,2MIPV@213118|Desulfobacterales	28221|Deltaproteobacteria	OU	signal peptide peptidase SppA	sppA	-	-	ko:K04773	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S49
k141_1406_1	1265505.ATUG01000002_gene1866	8.78e-101	295.0	COG0035@1|root,COG0035@2|Bacteria,1MV4N@1224|Proteobacteria,42NNR@68525|delta/epsilon subdivisions,2WK6M@28221|Deltaproteobacteria,2MJ9Q@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate	upp	GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.4.2.9	ko:K00761	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000	-	-	-	UPRTase
k141_4459_1	1348635.BBJY01000001_gene2669	6.81e-262	739.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,1XU0F@135623|Vibrionales	135623|Vibrionales	NT	Cache domain	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal,dCache_1
k141_4459_2	55601.VANGNB10_cII0178c	6.01e-163	467.0	COG2704@1|root,COG2704@2|Bacteria,1MVHH@1224|Proteobacteria,1RPTE@1236|Gammaproteobacteria,1XT7X@135623|Vibrionales	135623|Vibrionales	S	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane	dcuB	-	-	ko:K07792	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.13.1	-	-	DcuA_DcuB
k141_182_116	617140.AJZE01000084_gene2708	5.5e-92	271.0	COG0245@1|root,COG0245@2|Bacteria,1MVHA@1224|Proteobacteria,1S3RQ@1236|Gammaproteobacteria,1XTA4@135623|Vibrionales	135623|Vibrionales	I	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)	ispF	-	4.6.1.12	ko:K01770	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05637	RC00002,RC01440	ko00000,ko00001,ko00002,ko01000	-	-	-	YgbB
k141_182_117	1219065.VPR01S_28_00450	4.77e-96	287.0	COG1211@1|root,COG1211@2|Bacteria,1MY3B@1224|Proteobacteria,1S21S@1236|Gammaproteobacteria,1XTAS@135623|Vibrionales	135623|Vibrionales	I	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)	ispD	GO:0003674,GO:0003824,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0050518,GO:0070567,GO:0071704,GO:1901576	2.7.7.60	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD
k141_182_118	1219076.N646_1654	8.15e-45	146.0	COG2919@1|root,COG2919@2|Bacteria,1N7AA@1224|Proteobacteria,1SD8H@1236|Gammaproteobacteria,1XYBX@135623|Vibrionales	135623|Vibrionales	D	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic	ftsB	-	-	ko:K05589	-	-	-	-	ko00000,ko03036	-	-	-	DivIC
k141_182_119	998674.ATTE01000001_gene2830	6.02e-113	332.0	COG1968@1|root,COG1968@2|Bacteria,1MX02@1224|Proteobacteria,1RQQT@1236|Gammaproteobacteria,4607N@72273|Thiotrichales	72273|Thiotrichales	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
k141_182_120	55601.VANGNB10_cI0431	6.26e-61	192.0	COG0801@1|root,COG0801@2|Bacteria,1RHNN@1224|Proteobacteria,1S62M@1236|Gammaproteobacteria,1XXCH@135623|Vibrionales	135623|Vibrionales	H	COG0801 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase	folK-1	-	2.7.6.3	ko:K00950	ko00790,ko01100,map00790,map01100	M00126,M00841	R03503	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HPPK
k141_182_122	945543.VIBR0546_05254	4.46e-111	323.0	COG0344@1|root,COG0344@2|Bacteria,1RD4Z@1224|Proteobacteria,1RN1J@1236|Gammaproteobacteria,1XT3Z@135623|Vibrionales	135623|Vibrionales	I	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP	plsY	-	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	G3P_acyltransf
k141_182_123	675814.VIC_000893	5.26e-103	308.0	COG0596@1|root,COG0596@2|Bacteria,1QTTN@1224|Proteobacteria,1S0BI@1236|Gammaproteobacteria,1XTY0@135623|Vibrionales	135623|Vibrionales	S	hydrolases or acyltransferases (alpha beta hydrolase superfamily)	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
k141_182_124	55601.VANGNB10_cI0427	5.74e-220	609.0	COG0533@1|root,COG0533@2|Bacteria,1MU6S@1224|Proteobacteria,1RN8M@1236|Gammaproteobacteria,1XSZ3@135623|Vibrionales	135623|Vibrionales	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	-	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
k141_2159_1	96561.Dole_0360	3.13e-140	404.0	COG1075@1|root,COG1075@2|Bacteria,1NB6J@1224|Proteobacteria,42NSJ@68525|delta/epsilon subdivisions,2WM7M@28221|Deltaproteobacteria,2MIHU@213118|Desulfobacterales	28221|Deltaproteobacteria	S	acetyltransferases and hydrolases with the alpha beta hydrolase fold	lip	-	3.1.1.3	ko:K01046	ko00561,ko01100,map00561,map01100	M00098	R02250,R02687	RC00020,RC00037,RC00041,RC00094	ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_1
k141_1850_1	272123.Anacy_5275	1.12e-68	214.0	COG1662@1|root,COG3677@1|root,COG1662@2|Bacteria,COG3677@2|Bacteria,1G617@1117|Cyanobacteria	1117|Cyanobacteria	L	PFAM IS1 transposase	-	-	-	ko:K07480	-	-	-	-	ko00000	-	-	-	DDE_Tnp_IS1
k141_1850_2	313612.L8106_20198	3.87e-32	115.0	COG3677@1|root,COG3677@2|Bacteria,1G876@1117|Cyanobacteria,1HDAC@1150|Oscillatoriales	1117|Cyanobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	Zn_Tnp_IS1
k141_1850_3	1167006.UWK_02724	1.34e-230	639.0	arCOG14100@1|root,2Z924@2|Bacteria,1R4ME@1224|Proteobacteria,42XS5@68525|delta/epsilon subdivisions,2WXCJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	SIR2-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SIR2_2
k141_1159_1	1265505.ATUG01000003_gene528	4.33e-94	301.0	COG1148@1|root,COG1148@2|Bacteria,1QUM4@1224|Proteobacteria,42MPP@68525|delta/epsilon subdivisions,2WJ3U@28221|Deltaproteobacteria,2MJ2D@213118|Desulfobacterales	28221|Deltaproteobacteria	C	FAD binding domain	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_7,Pyr_redox_2
k141_2800_1	1232437.KL662015_gene1243	9.97e-19	78.6	2EIZA@1|root,33CQH@2|Bacteria,1NJDM@1224|Proteobacteria,42WT9@68525|delta/epsilon subdivisions,2WT1N@28221|Deltaproteobacteria,2MMAE@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Lipoprotein_19
k141_2800_2	1121396.KB893086_gene324	2.41e-17	77.4	COG3784@1|root,COG3784@2|Bacteria,1Q2I6@1224|Proteobacteria,42VRU@68525|delta/epsilon subdivisions,2WRCD@28221|Deltaproteobacteria,2MKZA@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF1318)	-	-	-	ko:K09978	-	-	-	-	ko00000	-	-	-	DUF1318
k141_4584_1	1232437.KL662027_gene2841	1.01e-183	533.0	COG0673@1|root,COG1063@1|root,COG0673@2|Bacteria,COG1063@2|Bacteria,1PDZZ@1224|Proteobacteria,42M63@68525|delta/epsilon subdivisions,2WJDW@28221|Deltaproteobacteria,2MJCU@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	ADH_zinc_N,GFO_IDH_MocA
k141_2437_1	1121396.KB893090_gene212	3.56e-113	340.0	COG3497@1|root,COG3497@2|Bacteria,1MX89@1224|Proteobacteria,42NJI@68525|delta/epsilon subdivisions,2WJI8@28221|Deltaproteobacteria,2MPX9@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Phage tail sheath C-terminal domain	-	-	-	ko:K06907	-	-	-	-	ko00000	-	-	-	Phage_sheath_1,Phage_sheath_1C
k141_2437_2	1346330.M472_13915	1.35e-60	189.0	2B9U6@1|root,32372@2|Bacteria,4PPY5@976|Bacteroidetes,1J13G@117747|Sphingobacteriia	976|Bacteroidetes	S	T4-like virus tail tube protein gp19	-	-	-	-	-	-	-	-	-	-	-	-	Phage_T4_gp19
k141_2160_1	118168.MC7420_6665	9.68e-38	150.0	COG2202@1|root,COG4251@1|root,COG2202@2|Bacteria,COG4251@2|Bacteria,1GHCI@1117|Cyanobacteria,1HI2A@1150|Oscillatoriales	1117|Cyanobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,GAF,HATPase_c,HisKA,Hpt,PAS_3,PAS_4,Response_reg
k141_2438_2	1121396.KB893052_gene3383	3.18e-24	103.0	COG4206@1|root,COG4206@2|Bacteria,1R57E@1224|Proteobacteria,42MKK@68525|delta/epsilon subdivisions,2WJ3K@28221|Deltaproteobacteria,2MJ51@213118|Desulfobacterales	28221|Deltaproteobacteria	H	TonB-dependent Receptor Plug Domain	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
k141_1857_1	1304885.AUEY01000009_gene1949	1.83e-81	251.0	COG4977@1|root,COG4977@2|Bacteria,1QTV9@1224|Proteobacteria,43CQR@68525|delta/epsilon subdivisions,2X7Y7@28221|Deltaproteobacteria,2MPPF@213118|Desulfobacterales	28221|Deltaproteobacteria	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	AraC_N,HTH_18
k141_1857_2	1304885.AUEY01000004_gene913	1.63e-210	601.0	COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,42MFH@68525|delta/epsilon subdivisions,2WIRW@28221|Deltaproteobacteria,2MIVE@213118|Desulfobacterales	28221|Deltaproteobacteria	T	PFAM sigma-54 factor interaction domain-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,PAS,PAS_4,PAS_9,Response_reg,Sigma54_activat
k141_2450_1	298386.PBPRC0040	5.69e-301	847.0	COG1203@1|root,COG1203@2|Bacteria,1MX99@1224|Proteobacteria,1RMM0@1236|Gammaproteobacteria,1XXC7@135623|Vibrionales	135623|Vibrionales	L	DEAD-like helicases superfamily	-	-	-	ko:K07012	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	DEAD,Helicase_C
k141_2450_2	1219072.VHA01S_030_00570	1.8e-15	72.4	2DMIY@1|root,32RWI@2|Bacteria,1RGHV@1224|Proteobacteria,1S1ZF@1236|Gammaproteobacteria,1XZFA@135623|Vibrionales	135623|Vibrionales	S	CRISPR_assoc	-	-	-	ko:K19126	-	-	-	-	ko00000,ko02048	-	-	-	CRISPR_assoc
k141_3862_1	702450.CUW_0390	6.42e-07	50.8	COG1283@1|root,COG1283@2|Bacteria,1TP4K@1239|Firmicutes,3VNX9@526524|Erysipelotrichia	526524|Erysipelotrichia	P	Na Pi-cotransporter II-like protein	-	-	-	ko:K03324	-	-	-	-	ko00000,ko02000	2.A.58.2	-	-	Na_Pi_cotrans,PhoU
k141_3862_2	1188252.AJYK01000031_gene1143	1.84e-47	152.0	2CC0C@1|root,32ZJ1@2|Bacteria,1R3EF@1224|Proteobacteria,1T671@1236|Gammaproteobacteria,1Y3DF@135623|Vibrionales	135623|Vibrionales	S	Protein of unknown function (DUF3297)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3297
k141_3862_3	1348635.BBJY01000001_gene2428	4.69e-83	258.0	COG0760@1|root,COG0760@2|Bacteria,1RDD3@1224|Proteobacteria,1RY54@1236|Gammaproteobacteria,1Y019@135623|Vibrionales	135623|Vibrionales	O	PPIC-type PPIASE domain	-	-	5.2.1.8	ko:K03769	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase
k141_3862_4	1348635.BBJY01000001_gene2429	2.99e-54	175.0	COG0760@1|root,COG0760@2|Bacteria,1QUCX@1224|Proteobacteria,1S6X5@1236|Gammaproteobacteria,1Y0RJ@135623|Vibrionales	135623|Vibrionales	O	NifZ domain	-	-	-	ko:K02597	-	-	-	-	ko00000	-	-	-	NifZ
k141_5180_1	269799.Gmet_1045	3.37e-280	781.0	COG2414@1|root,COG2414@2|Bacteria,1MWBB@1224|Proteobacteria,42MZJ@68525|delta/epsilon subdivisions,2WJK1@28221|Deltaproteobacteria,43S6G@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	PFAM aldehyde ferredoxin oxidoreductase	aorA	-	1.2.7.5	ko:K03738	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00309	R08571	RC00242	ko00000,ko00001,ko00002,ko01000	-	-	-	AFOR_C,AFOR_N
k141_5180_3	224719.Abm4_0169	1.2e-19	93.2	COG0476@1|root,arCOG01676@2157|Archaea,2XTYV@28890|Euryarchaeota,23P30@183925|Methanobacteria	183925|Methanobacteria	H	ThiF family	moeB	-	-	-	-	-	-	-	-	-	-	-	ThiF
k141_4185_1	675813.VIB_002642	2.13e-101	301.0	COG0604@1|root,COG0604@2|Bacteria,1MXCV@1224|Proteobacteria,1S0AH@1236|Gammaproteobacteria,1XVK0@135623|Vibrionales	135623|Vibrionales	C	Alcohol dehydrogenase GroES-like domain	-	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N_2
k141_4185_2	1219077.VAZ01S_043_00260	4.01e-51	166.0	COG0454@1|root,COG0456@2|Bacteria,1QYKG@1224|Proteobacteria,1RVJY@1236|Gammaproteobacteria,1XYE1@135623|Vibrionales	135623|Vibrionales	K	Acetyltransferase (GNAT) domain	-	-	-	ko:K03830	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_10
k141_2451_1	243277.VC_A0253	1.09e-44	151.0	COG0110@1|root,COG0110@2|Bacteria,1MUCJ@1224|Proteobacteria,1RPPT@1236|Gammaproteobacteria,1XVJ4@135623|Vibrionales	135623|Vibrionales	S	Bacterial transferase hexapeptide (six repeats)	-	-	2.3.1.28	ko:K00638	-	-	-	-	br01600,ko00000,ko01000,ko01504	-	-	-	Hexapep
k141_2812_3	485915.Dret_0357	1.74e-16	85.9	COG3206@1|root,COG3206@2|Bacteria,1QUY4@1224|Proteobacteria,42XUH@68525|delta/epsilon subdivisions,2WTFE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Chain length determinant protein	-	-	-	-	-	-	-	-	-	-	-	-	Wzz
k141_2812_4	1051646.VITU9109_02217	8.14e-53	194.0	COG1596@1|root,COG1596@2|Bacteria,1N7GP@1224|Proteobacteria,1RQSM@1236|Gammaproteobacteria,1XUWY@135623|Vibrionales	135623|Vibrionales	M	Periplasmic protein involved in polysaccharide export	-	-	-	-	-	-	-	-	-	-	-	-	Poly_export,SLBB
k141_5181_1	1453496.AT03_05665	1.27e-66	209.0	COG2875@1|root,COG2875@2|Bacteria,1MVYY@1224|Proteobacteria,1RWPQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	H	Precorrin-4 C(11)-methyltransferase	cobM	-	2.1.1.133,2.1.1.271	ko:K05936	ko00860,ko01100,map00860,map01100	-	R05181,R05810	RC00003,RC01294,RC02049	ko00000,ko00001,ko01000	-	-	-	TP_methylase
k141_5181_2	595494.Tola_1676	2.55e-76	234.0	COG2242@1|root,COG2242@2|Bacteria,1MVJX@1224|Proteobacteria,1RPJG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	H	precorrin-6y C5,15-methyltransferase	cobL	-	2.1.1.132,2.1.1.196	ko:K00595,ko:K02191	ko00860,ko01100,map00860,map01100	-	R05149,R05813,R07774	RC00003,RC01279,RC02052,RC02054	ko00000,ko00001,ko01000	-	-	-	MTS,Methyltransf_31,PCMT,TP_methylase
k141_5181_3	595494.Tola_1677	3.51e-53	175.0	COG2241@1|root,COG2241@2|Bacteria,1QUBH@1224|Proteobacteria,1T1S5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	H	Catalyzes the methylation of C-5 in cobalt-precorrin-6Y to form cobalt-precorrin-7W-a	cbiE	-	2.1.1.289	ko:K03399	ko00860,ko01100,map00860,map01100	-	R05813,R07775	RC00003,RC02052,RC02053	ko00000,ko00001,ko01000	-	-	-	TP_methylase
k141_1181_1	55601.VANGNB10_cII0286	4.88e-149	427.0	COG3732@1|root,COG3732@2|Bacteria,1QJR2@1224|Proteobacteria,1RQY1@1236|Gammaproteobacteria,1XVPG@135623|Vibrionales	135623|Vibrionales	G	Sorbitol phosphotransferase enzyme II N-terminus	-	-	2.7.1.198	ko:K02782,ko:K02783	ko00051,ko02060,map00051,map02060	M00280	R05820	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.4.1	-	-	EIIBC-GUT_C,EIIBC-GUT_N
k141_1181_2	1517681.HW45_25990	1.09e-115	333.0	COG3730@1|root,COG3730@2|Bacteria,1MXS5@1224|Proteobacteria,1RQTZ@1236|Gammaproteobacteria,1XVJV@135623|Vibrionales	135623|Vibrionales	G	PTS system enzyme II sorbitol-specific factor	-	-	-	ko:K02783	ko00051,ko02060,map00051,map02060	M00280	R05820	RC00017,RC03206	ko00000,ko00001,ko00002,ko02000	4.A.4.1	-	-	EII-GUT
k141_1181_3	1460640.JCM19046_813	1.08e-15	78.2	COG0176@1|root,COG0176@2|Bacteria	2|Bacteria	G	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	tal	-	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
k141_1181_4	1332071.L581_3939	7.37e-88	268.0	COG1349@1|root,COG1349@2|Bacteria,1MV49@1224|Proteobacteria,1RRR5@1236|Gammaproteobacteria,400UJ@613|Serratia	1236|Gammaproteobacteria	K	Transcriptional regulator	glpR_2	-	-	-	-	-	-	-	-	-	-	-	DeoRC,HTH_DeoR
k141_1181_5	1280001.BAOA01000034_gene2190	1.11e-174	495.0	COG1609@1|root,COG1609@2|Bacteria,1MU1G@1224|Proteobacteria,1RMSP@1236|Gammaproteobacteria,1XVXP@135623|Vibrionales	135623|Vibrionales	K	helix_turn _helix lactose operon repressor	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
k141_1181_6	675814.VIC_003134	0.000108	43.5	COG2211@1|root,COG2211@2|Bacteria,1MVUM@1224|Proteobacteria,1RP5J@1236|Gammaproteobacteria,1XT0V@135623|Vibrionales	135623|Vibrionales	G	COG2211 Na melibiose symporter and related transporters	-	-	-	ko:K11104	-	-	-	-	ko00000,ko02000	2.A.2.1	-	-	MFS_2
k141_3192_1	96561.Dole_2743	1.12e-100	305.0	COG0490@1|root,COG1226@1|root,COG0490@2|Bacteria,COG1226@2|Bacteria,1MU1R@1224|Proteobacteria,42MW6@68525|delta/epsilon subdivisions,2WIYU@28221|Deltaproteobacteria,2MI88@213118|Desulfobacterales	28221|Deltaproteobacteria	P	PFAM TrkA-N domain	-	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans_2,TrkA_C,TrkA_N
k141_3192_2	1121405.dsmv_0344	9.44e-52	172.0	COG0212@1|root,COG0212@2|Bacteria,1MZG0@1224|Proteobacteria,42U47@68525|delta/epsilon subdivisions,2WP68@28221|Deltaproteobacteria,2MK5D@213118|Desulfobacterales	28221|Deltaproteobacteria	H	5-formyltetrahydrofolate cyclo-ligase family	-	-	6.3.3.2	ko:K01934	ko00670,ko01100,map00670,map01100	-	R02301	RC00183	ko00000,ko00001,ko01000	-	-	-	5-FTHF_cyc-lig
k141_3192_3	933262.AXAM01000008_gene1971	6.69e-175	503.0	COG0172@1|root,COG0172@2|Bacteria,1MUJF@1224|Proteobacteria,42M7H@68525|delta/epsilon subdivisions,2WIT7@28221|Deltaproteobacteria,2MI2A@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iAF987.Gmet_3528	Seryl_tRNA_N,tRNA-synt_2b
k141_3192_4	1304885.AUEY01000022_gene3403	2.01e-218	615.0	COG0498@1|root,COG0498@2|Bacteria,1MUWQ@1224|Proteobacteria,42M1W@68525|delta/epsilon subdivisions,2WK53@28221|Deltaproteobacteria,2MIJV@213118|Desulfobacterales	28221|Deltaproteobacteria	E	TIGRFAM threonine synthase	thrC	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
k141_2453_1	1071379.XP_004182230.1	1.79e-37	144.0	COG0620@1|root,KOG2263@2759|Eukaryota,38GZS@33154|Opisthokonta,3NW49@4751|Fungi,3QN7P@4890|Ascomycota,3RRUW@4891|Saccharomycetes,3S02A@4893|Saccharomycetaceae	4751|Fungi	E	to Saccharomyces cerevisiae MET6 (YER091C)	MET6	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003871,GO:0005488,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006144,GO:0006520,GO:0006534,GO:0006555,GO:0006725,GO:0006790,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008270,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009092,GO:0009112,GO:0009113,GO:0009266,GO:0009277,GO:0009408,GO:0009605,GO:0009607,GO:0009628,GO:0009986,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016741,GO:0017144,GO:0018130,GO:0019279,GO:0019280,GO:0019438,GO:0019752,GO:0030312,GO:0030446,GO:0031012,GO:0031347,GO:0031349,GO:0032259,GO:0033554,GO:0034605,GO:0034641,GO:0035821,GO:0042084,GO:0042085,GO:0042440,GO:0043167,GO:0043169,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044003,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044403,GO:0044416,GO:0044419,GO:0044421,GO:0044424,GO:0044444,GO:0044464,GO:0046083,GO:0046084,GO:0046112,GO:0046148,GO:0046394,GO:0046483,GO:0046872,GO:0046914,GO:0048518,GO:0048583,GO:0048584,GO:0050667,GO:0050789,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052251,GO:0052255,GO:0052509,GO:0052510,GO:0055086,GO:0062039,GO:0062040,GO:0065007,GO:0071265,GO:0071266,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0075136,GO:0080134,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.1.1.14	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	M00017	R04405,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	iMM904.YER091C,iND750.YER091C	Meth_synt_1,Meth_synt_2
k141_1858_1	1348635.BBJY01000020_gene2730	2.8e-91	272.0	COG0564@1|root,COG0564@2|Bacteria,1N8GW@1224|Proteobacteria,1RMZ7@1236|Gammaproteobacteria,1XSJX@135623|Vibrionales	135623|Vibrionales	J	COG0564 Pseudouridylate synthases, 23S RNA-specific	truC	GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360	5.4.99.26	ko:K06175	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_2
k141_1858_3	223926.28805673	7.53e-102	302.0	COG0142@1|root,COG0142@2|Bacteria,1MWNG@1224|Proteobacteria,1RMKY@1236|Gammaproteobacteria,1XTUM@135623|Vibrionales	135623|Vibrionales	H	Belongs to the FPP GGPP synthase family	ispA	-	2.5.1.1,2.5.1.10	ko:K00795	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364	R01658,R02003	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
k141_1182_1	1499684.CCNP01000019_gene2206	1.01e-80	245.0	COG0406@1|root,COG0406@2|Bacteria,1VDCB@1239|Firmicutes,249VH@186801|Clostridia,36GCW@31979|Clostridiaceae	186801|Clostridia	G	Belongs to the phosphoglycerate mutase family	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
k141_202_1	35703.DQ02_18710	0.00097	46.6	2EFPB@1|root,32SG8@2|Bacteria,1N286@1224|Proteobacteria,1SAJ9@1236|Gammaproteobacteria,3WZGD@544|Citrobacter	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_202_3	1345695.CLSA_c31800	2.77e-16	81.6	COG1357@1|root,COG1357@2|Bacteria,1VNCI@1239|Firmicutes,24EAN@186801|Clostridia,36ECH@31979|Clostridiaceae	186801|Clostridia	S	PFAM Pentapeptide repeats (8 copies)	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_202_5	1410653.JHVC01000008_gene3070	4.74e-33	121.0	2EE7B@1|root,3381W@2|Bacteria,1VAIC@1239|Firmicutes,24PS3@186801|Clostridia,36M8G@31979|Clostridiaceae	186801|Clostridia	S	Domain of unknown function (DUF4280)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4280
k141_202_6	398512.JQKC01000010_gene179	2.73e-49	190.0	COG3501@1|root,COG3501@2|Bacteria,1TSS0@1239|Firmicutes,25BBM@186801|Clostridia	186801|Clostridia	S	Rhs element vgr protein	-	-	-	-	-	-	-	-	-	-	-	-	Phage_GPD
k141_5182_1	439235.Dalk_0407	7.7e-134	395.0	COG4992@1|root,COG4992@2|Bacteria,1MV3C@1224|Proteobacteria,42MHH@68525|delta/epsilon subdivisions,2WIMW@28221|Deltaproteobacteria,2MHRT@213118|Desulfobacterales	28221|Deltaproteobacteria	E	TIGRFAM acetylornithine and succinylornithine	argD	-	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	iAF987.Gmet_0204	Aminotran_3
k141_5182_2	96561.Dole_2492	3.65e-52	174.0	COG0078@1|root,COG0078@2|Bacteria,1MUFM@1224|Proteobacteria,42M0Q@68525|delta/epsilon subdivisions,2WJ3G@28221|Deltaproteobacteria,2MHVW@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline	argF	GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.1.3.3,2.1.3.9	ko:K00611,ko:K09065	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01398,R07245	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
k141_2813_1	999423.HMPREF9161_01802	4.35e-54	179.0	COG0765@1|root,COG0765@2|Bacteria,1TPM3@1239|Firmicutes,4H1UP@909932|Negativicutes	909932|Negativicutes	P	ABC transporter, permease protein	glnP	-	-	ko:K02029	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	BPD_transp_1
k141_2813_2	1007103.AFHW01000059_gene4133	2.41e-95	286.0	COG1126@1|root,COG1126@2|Bacteria,1TNYD@1239|Firmicutes,4H9WY@91061|Bacilli,26QWX@186822|Paenibacillaceae	91061|Bacilli	E	ABC transporter	glnQ2	-	3.6.3.21	ko:K02028	-	M00236	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.3	-	-	ABC_tran
k141_4186_1	1121403.AUCV01000033_gene3626	0.0	1003.0	COG0247@1|root,COG0277@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,1MU43@1224|Proteobacteria,42MZC@68525|delta/epsilon subdivisions,2WKRK@28221|Deltaproteobacteria,2MIYS@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Protein of unknown function (DUF3683)	-	-	-	-	-	-	-	-	-	-	-	-	CCG,DUF3683,FAD-oxidase_C,FAD_binding_4,Fer4_10,Fer4_8
k141_5183_1	1051646.VITU9109_05161	1.27e-56	178.0	2CF4K@1|root,332IV@2|Bacteria,1N9BX@1224|Proteobacteria,1SCNS@1236|Gammaproteobacteria,1XZ0X@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_204_2	997350.HMPREF9129_1074	9.56e-58	200.0	COG0653@1|root,COG0653@2|Bacteria,1TPEY@1239|Firmicutes,247N2@186801|Clostridia,22G91@1570339|Peptoniphilaceae	186801|Clostridia	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	-	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	Helicase_C,SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
k141_1183_1	1121405.dsmv_3057	5.23e-102	311.0	COG2605@1|root,COG2605@2|Bacteria,1QW1A@1224|Proteobacteria,42N0X@68525|delta/epsilon subdivisions,2WJYP@28221|Deltaproteobacteria,2MHZ0@213118|Desulfobacterales	28221|Deltaproteobacteria	S	PFAM GHMP kinase	-	-	2.7.1.168	ko:K07031	ko00540,map00540	-	R09770	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
k141_1183_2	1265505.ATUG01000003_gene114	5.66e-136	390.0	COG0752@1|root,COG0752@2|Bacteria,1MVCJ@1224|Proteobacteria,42MNQ@68525|delta/epsilon subdivisions,2WJJW@28221|Deltaproteobacteria,2MI7B@213118|Desulfobacterales	28221|Deltaproteobacteria	J	PFAM glycyl-tRNA synthetase alpha subunit	glyQ	-	6.1.1.14	ko:K01878	ko00970,map00970	M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iAF987.Gmet_2942	tRNA-synt_2e
k141_2814_1	4959.XP_459519.2	3.27e-07	57.8	KOG1210@1|root,KOG1210@2759|Eukaryota,38GV8@33154|Opisthokonta,3NYA2@4751|Fungi,3QQ55@4890|Ascomycota,3RTS1@4891|Saccharomycetes,47A3S@766764|Debaryomycetaceae	4751|Fungi	Q	reductase	TSC10	GO:0000234,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005741,GO:0005783,GO:0005789,GO:0005811,GO:0006464,GO:0006497,GO:0006505,GO:0006506,GO:0006629,GO:0006643,GO:0006644,GO:0006650,GO:0006661,GO:0006664,GO:0006665,GO:0006666,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008610,GO:0008654,GO:0008757,GO:0009058,GO:0009059,GO:0009247,GO:0009987,GO:0012505,GO:0016020,GO:0016491,GO:0016614,GO:0016616,GO:0016651,GO:0016740,GO:0016741,GO:0019538,GO:0019637,GO:0019867,GO:0030148,GO:0031090,GO:0031966,GO:0031967,GO:0031968,GO:0031975,GO:0031984,GO:0032259,GO:0034645,GO:0036211,GO:0042157,GO:0042158,GO:0042175,GO:0042180,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044281,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044432,GO:0044444,GO:0044446,GO:0044464,GO:0045017,GO:0046467,GO:0046474,GO:0046486,GO:0046488,GO:0046519,GO:0047560,GO:0055114,GO:0071704,GO:0090407,GO:0097164,GO:0098588,GO:0098805,GO:0098827,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:1903509	1.1.1.102,1.1.1.56	ko:K00039,ko:K04708	ko00040,ko00600,ko01100,map00040,map00600,map01100	M00094,M00099	R01895,R02978	RC00089,RC00102	ko00000,ko00001,ko00002,ko01000	-	-	-	adh_short
k141_2454_1	1121324.CLIT_13c02340	6.88e-31	119.0	COG1947@1|root,COG1947@2|Bacteria,1TPXV@1239|Firmicutes,24898@186801|Clostridia,25QT8@186804|Peptostreptococcaceae	186801|Clostridia	F	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol	ispE	-	2.7.1.148	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05634	RC00002,RC01439	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
k141_2454_2	96561.Dole_2815	3.45e-150	443.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,42NB6@68525|delta/epsilon subdivisions,2WIWE@28221|Deltaproteobacteria,2MHQQ@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Belongs to the peptidase S1C family	degP	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
k141_2454_3	1304885.AUEY01000005_gene821	4.79e-05	43.1	2EAFJ@1|root,334IY@2|Bacteria,1NA2Y@1224|Proteobacteria,42VJ1@68525|delta/epsilon subdivisions,2WRKE@28221|Deltaproteobacteria,2MKY4@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF1844)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1844
k141_1184_1	1304885.AUEY01000046_gene9	3.05e-191	549.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,42M51@68525|delta/epsilon subdivisions,2WIVD@28221|Deltaproteobacteria,2MHZ9@213118|Desulfobacterales	28221|Deltaproteobacteria	NU	type II secretion system	pulE-3	-	-	ko:K02454	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSE,T2SSE_N
k141_205_1	1304885.AUEY01000011_gene1735	1.04e-174	535.0	COG1924@1|root,COG3580@1|root,COG3581@1|root,COG1924@2|Bacteria,COG3580@2|Bacteria,COG3581@2|Bacteria,1PKG6@1224|Proteobacteria,42MY4@68525|delta/epsilon subdivisions,2WJFI@28221|Deltaproteobacteria,2MIP0@213118|Desulfobacterales	68525|delta/epsilon subdivisions	I	BadF BadG BcrA BcrD	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG,DUF2229
k141_1863_2	457421.CBFG_05565	8e-19	82.4	COG0110@1|root,COG0110@2|Bacteria,1TPKX@1239|Firmicutes,249X2@186801|Clostridia	186801|Clostridia	M	Acetyltransferase (Isoleucine patch superfamily)	vat	-	-	ko:K18234	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	Hexapep
k141_1864_2	1042326.AZNV01000002_gene4755	3.48e-05	45.4	COG1004@1|root,COG1004@2|Bacteria,1MW5U@1224|Proteobacteria,2TREV@28211|Alphaproteobacteria,4B9FY@82115|Rhizobiaceae	28211|Alphaproteobacteria	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	algD	-	1.1.1.132	ko:K00066	ko00051,ko00520,ko02020,map00051,map00520,map02020	-	R00880	RC00291	ko00000,ko00001,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
k141_3193_3	1472716.KBK24_0117010	4.63e-42	141.0	COG1396@1|root,COG1396@2|Bacteria,1R337@1224|Proteobacteria,2WIF1@28216|Betaproteobacteria,1KF4Y@119060|Burkholderiaceae	2|Bacteria	K	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
k141_3193_4	930166.CD58_22215	7.56e-45	150.0	29WIV@1|root,30I53@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_3193_5	244582.JQAK01000002_gene496	6.96e-17	80.9	2EJ7P@1|root,33CYV@2|Bacteria,1NKMY@1224|Proteobacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF637
k141_2841_72	1123355.JHYO01000005_gene846	2.12e-50	201.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2TQS3@28211|Alphaproteobacteria,36XKH@31993|Methylocystaceae	28211|Alphaproteobacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS,PAS_3,PAS_4,PAS_9,Response_reg
k141_2841_73	926561.KB900621_gene2825	1.32e-144	430.0	COG0415@1|root,COG0415@2|Bacteria,1UDZT@1239|Firmicutes,249FJ@186801|Clostridia,3WAHJ@53433|Halanaerobiales	186801|Clostridia	L	PFAM DNA photolyase	phr	-	4.1.99.3	ko:K01669	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_photolyase
k141_2841_74	1230342.CTM_15038	5.73e-100	304.0	COG1683@1|root,COG3272@1|root,COG1683@2|Bacteria,COG3272@2|Bacteria,1TQX3@1239|Firmicutes,24A3W@186801|Clostridia,36FUZ@31979|Clostridiaceae	186801|Clostridia	S	Protein of unknown function (DUF1722)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1722,DUF523
k141_2841_79	293826.Amet_0108	6.62e-71	218.0	COG1595@1|root,COG1595@2|Bacteria,1V9ZH@1239|Firmicutes,24NF2@186801|Clostridia,36KPM@31979|Clostridiaceae	186801|Clostridia	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
k141_2841_80	1304284.L21TH_1966	4.83e-126	379.0	2F0NN@1|root,33TR4@2|Bacteria,1VSJ0@1239|Firmicutes,24ZWE@186801|Clostridia,36R0M@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_2841_81	1385513.N780_15530	7.11e-64	209.0	COG3153@1|root,COG3153@2|Bacteria	2|Bacteria	S	transferase activity, transferring acyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_9
k141_2841_82	1487921.DP68_00935	1.25e-98	303.0	COG1690@1|root,COG1690@2|Bacteria,1TPJ2@1239|Firmicutes,2481V@186801|Clostridia,36EU8@31979|Clostridiaceae	186801|Clostridia	S	tRNA-splicing ligase RtcB	-	-	6.5.1.3	ko:K14415,ko:K18148	ko01501,map01501	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	RtcB
k141_2841_83	935836.JAEL01000008_gene3945	8.99e-67	209.0	COG1896@1|root,COG1896@2|Bacteria,1V7E8@1239|Firmicutes	1239|Firmicutes	S	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K06952	-	-	-	-	ko00000	-	-	-	DUF429,HD_3
k141_2841_85	1301100.HG529332_gene4571	3.56e-69	215.0	COG1396@1|root,COG3837@1|root,COG1396@2|Bacteria,COG3837@2|Bacteria,1V3VT@1239|Firmicutes,25EB4@186801|Clostridia,36W73@31979|Clostridiaceae	186801|Clostridia	K	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,HTH_3
k141_2841_86	457570.Nther_2477	3.12e-74	237.0	COG1180@1|root,COG1180@2|Bacteria,1TPK2@1239|Firmicutes,24871@186801|Clostridia	186801|Clostridia	C	glycyl-radical enzyme activating protein family	csdA	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4,Fer4_12,Radical_SAM
k141_2841_87	1347392.CCEZ01000049_gene1637	0.0	1175.0	COG1882@1|root,COG1882@2|Bacteria,1TPTF@1239|Firmicutes,247YY@186801|Clostridia,36EFE@31979|Clostridiaceae	186801|Clostridia	C	Glycine radical enzyme that catalyzes the cleavage of a C-N bond in choline, producing trimethylamine (TMA) and acetaldehyde	-	-	2.3.1.54,4.3.99.4	ko:K00656,ko:K20038	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	-	R00212,R06987	RC00004,RC01181,RC02742,RC02833	ko00000,ko00001,ko01000	-	-	-	Gly_radical,PFL-like
k141_2841_88	86416.Clopa_4624	1.12e-109	324.0	COG0345@1|root,COG0345@2|Bacteria,1TP1E@1239|Firmicutes,247SR@186801|Clostridia,36E5T@31979|Clostridiaceae	186801|Clostridia	E	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline	proC	-	1.5.1.2	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	M00015	R01248,R01251,R03291,R03293	RC00054,RC00083	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_oxidored,P5CR_dimer
k141_2841_92	1033737.CAEV01000039_gene2086	1.65e-205	599.0	COG2309@1|root,COG2309@2|Bacteria,1TSPE@1239|Firmicutes,24A6S@186801|Clostridia,36DC3@31979|Clostridiaceae	186801|Clostridia	E	Thermophilic metalloprotease (M29)	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M29
k141_4959_2	945550.VISI1226_15871	6.92e-82	243.0	COG0822@1|root,COG0822@2|Bacteria,1RD5K@1224|Proteobacteria,1S3P1@1236|Gammaproteobacteria,1XWW7@135623|Vibrionales	135623|Vibrionales	C	A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters	iscU	-	-	ko:K04488	-	-	-	-	ko00000	-	-	-	NifU_N
k141_4959_3	523791.Kkor_1504	3.59e-61	189.0	COG0316@1|root,COG0316@2|Bacteria,1RH6T@1224|Proteobacteria,1S5XD@1236|Gammaproteobacteria,1XKH0@135619|Oceanospirillales	135619|Oceanospirillales	S	Belongs to the HesB IscA family	iscA	-	-	ko:K13628	-	-	-	-	ko00000,ko03016	-	-	-	Fe-S_biosyn
k141_4959_4	674977.VMC_07270	1.97e-77	235.0	COG1076@1|root,COG1076@2|Bacteria,1RHZX@1224|Proteobacteria,1S9YH@1236|Gammaproteobacteria,1XTU9@135623|Vibrionales	135623|Vibrionales	O	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA	hscB	GO:0006457,GO:0008150,GO:0009987	-	ko:K04082	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,HSCB_C
k141_4959_5	675814.VIC_002117	0.0	966.0	COG0443@1|root,COG0443@2|Bacteria,1MVQI@1224|Proteobacteria,1RN74@1236|Gammaproteobacteria,1XT9W@135623|Vibrionales	135623|Vibrionales	O	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB	hscA	GO:0006457,GO:0008150,GO:0009987	-	ko:K04044	-	-	-	-	ko00000,ko03110	1.A.33	-	-	HSP70
k141_4959_6	945543.VIBR0546_19439	2.56e-70	212.0	COG0633@1|root,COG0633@2|Bacteria,1RHDC@1224|Proteobacteria,1S5XW@1236|Gammaproteobacteria,1XXAG@135623|Vibrionales	135623|Vibrionales	C	Ferredoxin	fdx	-	-	ko:K04755	-	-	-	-	ko00000	-	-	-	Fer2
k141_4959_7	1219065.VPR01S_10_01200	2.15e-38	128.0	COG2975@1|root,COG2975@2|Bacteria,1N7C1@1224|Proteobacteria,1SC9F@1236|Gammaproteobacteria,1XYVQ@135623|Vibrionales	135623|Vibrionales	S	protein conserved in bacteria	iscX	-	-	-	-	-	-	-	-	-	-	-	Fe-S_assembly
k141_4959_8	345073.VC395_0772	2.91e-173	494.0	COG0260@1|root,COG0260@2|Bacteria,1MUIN@1224|Proteobacteria,1RNFI@1236|Gammaproteobacteria,1XUTG@135623|Vibrionales	135623|Vibrionales	E	Probably plays an important role in intracellular peptide degradation	pepB	GO:0003674,GO:0003824,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:0140096,GO:1901564	3.4.11.23	ko:K07751	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	DUF3663,Peptidase_M17
k141_3941_1	1175306.GWL_25170	2.63e-11	63.9	COG3495@1|root,COG3495@2|Bacteria,1RB8H@1224|Proteobacteria,2VSUS@28216|Betaproteobacteria	28216|Betaproteobacteria	S	protein conserved in bacteria	-	-	-	ko:K09950	-	-	-	-	ko00000	-	-	-	DUF3299
k141_3941_2	316275.VSAL_II0464	2.61e-31	110.0	COG3530@1|root,COG3530@2|Bacteria,1N7GT@1224|Proteobacteria,1SCBX@1236|Gammaproteobacteria,1XYDT@135623|Vibrionales	135623|Vibrionales	S	protein conserved in bacteria	STM2426	-	-	ko:K09954	-	-	-	-	ko00000	-	-	-	QSregVF_b
k141_3941_3	345073.VC395_A0157	1.2e-68	212.0	COG3034@1|root,COG3034@2|Bacteria,1MXY6@1224|Proteobacteria,1S66I@1236|Gammaproteobacteria,1XXH1@135623|Vibrionales	135623|Vibrionales	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
k141_3941_4	316275.VSAL_II0522	9.62e-91	296.0	COG0457@1|root,COG0457@2|Bacteria,1MXK4@1224|Proteobacteria,1RNFM@1236|Gammaproteobacteria,1XU0S@135623|Vibrionales	135623|Vibrionales	S	Oxygen tolerance	-	-	-	-	-	-	-	-	-	-	-	-	BatD
k141_3941_5	55601.VANGNB10_cII0790	1.21e-154	466.0	COG0457@1|root,COG2304@1|root,COG0457@2|Bacteria,COG2304@2|Bacteria,1MW51@1224|Proteobacteria,1RMD3@1236|Gammaproteobacteria,1XVCX@135623|Vibrionales	135623|Vibrionales	S	protein containing a von Willebrand factor type A (vWA) domain	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	TPR_1,TPR_19,TPR_2,VWA_2
k141_3941_6	1348635.BBJY01000003_gene3835	8.21e-158	450.0	COG2304@1|root,COG2304@2|Bacteria,1MXQ7@1224|Proteobacteria,1RMDX@1236|Gammaproteobacteria,1XU2A@135623|Vibrionales	135623|Vibrionales	S	protein containing a von Willebrand factor type A (vWA) domain	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA
k141_3941_7	243277.VC_A0173	5.17e-60	190.0	2C5QF@1|root,331W9@2|Bacteria,1N7AE@1224|Proteobacteria,1SCH2@1236|Gammaproteobacteria,1XXHT@135623|Vibrionales	135623|Vibrionales	S	Domain of unknown function (DUF4381)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4381
k141_3941_8	796620.VIBC2010_06484	1.02e-115	343.0	COG1721@1|root,COG1721@2|Bacteria,1Q7RR@1224|Proteobacteria,1RNNP@1236|Gammaproteobacteria,1XSBV@135623|Vibrionales	135623|Vibrionales	S	conserved protein (some members contain a von Willebrand factor type A (vWA) domain)	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
k141_3941_10	1219065.VPR01S_05_01640	2.92e-19	80.1	2AWN1@1|root,31NIT@2|Bacteria,1QK9F@1224|Proteobacteria,1TICX@1236|Gammaproteobacteria,1XYW9@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_314_1	1116375.VEJY3_19301	7.39e-152	430.0	COG0834@1|root,COG0834@2|Bacteria,1MVT6@1224|Proteobacteria,1RNTT@1236|Gammaproteobacteria,1XZ17@135623|Vibrionales	135623|Vibrionales	ET	belongs to the bacterial solute-binding protein 3 family	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
k141_314_2	1116375.VEJY3_19306	2.26e-79	240.0	COG0765@1|root,COG0765@2|Bacteria,1MX2Y@1224|Proteobacteria,1RNQX@1236|Gammaproteobacteria,1XYU2@135623|Vibrionales	135623|Vibrionales	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02029	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	BPD_transp_1
k141_5230_1	585394.RHOM_11840	7.49e-07	57.4	COG1106@1|root,COG1106@2|Bacteria,1TSBY@1239|Firmicutes,249DS@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	ko:K06926	-	-	-	-	ko00000	-	-	-	AAA_21
k141_2265_1	96561.Dole_2292	3.3e-126	383.0	COG0025@1|root,COG0569@1|root,COG0025@2|Bacteria,COG0569@2|Bacteria,1QTUE@1224|Proteobacteria,43BRM@68525|delta/epsilon subdivisions,2WM4A@28221|Deltaproteobacteria,2MHXR@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family	-	-	-	ko:K03316	-	-	-	-	ko00000	2.A.36	-	-	Na_H_Exchanger,TrkA_N
k141_3236_2	1304885.AUEY01000051_gene1501	6.42e-14	71.6	COG3177@1|root,COG3177@2|Bacteria,1PMMB@1224|Proteobacteria,42Q5D@68525|delta/epsilon subdivisions,2WKSH@28221|Deltaproteobacteria,2MN0P@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Fic/DOC family	-	-	-	-	-	-	-	-	-	-	-	-	Fic
k141_3639_1	1167006.UWK_02872	0.0	1036.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2WJ8D@28221|Deltaproteobacteria,2MICU@213118|Desulfobacterales	28221|Deltaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
k141_4960_1	694431.DESACE_06760	4.6e-24	103.0	COG2086@1|root,COG2086@2|Bacteria,1MVH6@1224|Proteobacteria,42RCI@68525|delta/epsilon subdivisions,2WMYC@28221|Deltaproteobacteria,2M7KH@213113|Desulfurellales	28221|Deltaproteobacteria	C	Electron transfer flavoprotein domain	etfB-7	-	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
k141_2842_1	400668.Mmwyl1_1686	1.51e-58	197.0	COG0747@1|root,COG0747@2|Bacteria,1MUZH@1224|Proteobacteria,1RNES@1236|Gammaproteobacteria,1XH6Y@135619|Oceanospirillales	135619|Oceanospirillales	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
k141_2842_2	1122929.KB908231_gene3638	5.07e-21	92.0	COG0601@1|root,COG0601@2|Bacteria,1MU8Z@1224|Proteobacteria,2TR3F@28211|Alphaproteobacteria	28211|Alphaproteobacteria	EP	COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
k141_1946_3	1286171.EAL2_c22190	7.6e-128	383.0	COG0457@1|root,COG1396@1|root,COG0457@2|Bacteria,COG1396@2|Bacteria,1VHJ0@1239|Firmicutes,247R0@186801|Clostridia	186801|Clostridia	K	Helix-turn-helix domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19,HTH_3,TPR_12,TPR_8
k141_1946_4	865861.AZSU01000006_gene1182	4.21e-67	216.0	COG1475@1|root,COG1475@2|Bacteria,1TQ2B@1239|Firmicutes,249VV@186801|Clostridia,36DTS@31979|Clostridiaceae	186801|Clostridia	K	Belongs to the ParB family	spo0J	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
k141_3942_1	1265505.ATUG01000003_gene790	2.72e-50	175.0	COG2199@1|root,COG2199@2|Bacteria,1NV1F@1224|Proteobacteria,43CS0@68525|delta/epsilon subdivisions,2X7ZM@28221|Deltaproteobacteria,2MNZV@213118|Desulfobacterales	28221|Deltaproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
k141_315_2	94122.Shewana3_0736	3.08e-17	88.6	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,1RN52@1236|Gammaproteobacteria,2Q9W2@267890|Shewanellaceae	1236|Gammaproteobacteria	T	PFAM ATP-binding region, ATPase domain protein domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CHASE5,HATPase_c
k141_2266_1	1122197.ATWI01000014_gene4	7.5e-105	312.0	COG2801@1|root,COG2801@2|Bacteria,1MVXQ@1224|Proteobacteria,1RR4F@1236|Gammaproteobacteria,465JZ@72275|Alteromonadaceae	1236|Gammaproteobacteria	L	COG2801 Transposase and inactivated derivatives	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve
k141_2266_2	675816.VIA_002823	2.5e-29	106.0	COG2963@1|root,COG2963@2|Bacteria,1N3E0@1224|Proteobacteria,1S9T7@1236|Gammaproteobacteria,1XXQ1@135623|Vibrionales	135623|Vibrionales	L	Transposase	-	-	-	ko:K07483	-	-	-	-	ko00000	-	-	-	HTH_Tnp_1
k141_3640_1	313612.L8106_22596	8.37e-50	163.0	COG3153@1|root,COG3153@2|Bacteria,1G6H9@1117|Cyanobacteria,1HBUU@1150|Oscillatoriales	1117|Cyanobacteria	S	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_7,Acetyltransf_9
k141_3237_1	491952.Mar181_0085	9.62e-07	49.7	COG0601@1|root,COG0601@2|Bacteria,1MU8Z@1224|Proteobacteria,1RNJ1@1236|Gammaproteobacteria,1XIPB@135619|Oceanospirillales	135619|Oceanospirillales	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02033,ko:K12369	ko02010,ko02024,map02010,map02024	M00239,M00324	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
k141_3237_2	1208321.D104_11435	4.54e-103	306.0	COG1173@1|root,COG1173@2|Bacteria,1MUG0@1224|Proteobacteria,1RN08@1236|Gammaproteobacteria,1XIY8@135619|Oceanospirillales	135619|Oceanospirillales	EP	transporter	-	-	-	ko:K02034,ko:K12370	ko02010,ko02024,map02010,map02024	M00239,M00324	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
k141_5231_1	55601.VANGNB10_cI1091c	5.88e-57	182.0	COG3070@1|root,COG3070@2|Bacteria,1RDWD@1224|Proteobacteria,1S496@1236|Gammaproteobacteria,1XUVA@135623|Vibrionales	135623|Vibrionales	K	COG3070 Regulator of competence-specific genes	tfoX	GO:0006810,GO:0007154,GO:0008150,GO:0009290,GO:0009292,GO:0009294,GO:0009605,GO:0009987,GO:0009991,GO:0015931,GO:0030420,GO:0031668,GO:0044764,GO:0050657,GO:0050896,GO:0051027,GO:0051179,GO:0051234,GO:0051704,GO:0051716,GO:0071496,GO:0071702,GO:0071705,GO:0098657	-	ko:K07343	-	-	-	-	ko00000	-	-	-	TfoX_C,TfoX_N
k141_5231_2	675815.VOA_002127	1.51e-129	375.0	COG1609@1|root,COG1609@2|Bacteria,1MVUR@1224|Proteobacteria,1RN2K@1236|Gammaproteobacteria,1XU47@135623|Vibrionales	135623|Vibrionales	K	Is the main repressor of the genes involved in the de novo synthesis of purine nucleotides, regulating purB, purC, purEK, purF, purHD, purL, purMN and guaBA expression. PurR is allosterically activated to bind its cognate DNA by binding the purine corepressors, hypoxanthine or guanine, thereby effecting transcription repression	purR	GO:0003674,GO:0003700,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2001141	-	ko:K03604	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
k141_1947_1	1173027.Mic7113_3144	3.42e-57	205.0	COG0515@1|root,COG3899@1|root,COG4191@1|root,COG0515@2|Bacteria,COG3899@2|Bacteria,COG4191@2|Bacteria,1GBKM@1117|Cyanobacteria,1H7D9@1150|Oscillatoriales	1117|Cyanobacteria	KLT	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GAF,HATPase_c,HisKA,Pkinase
k141_1271_1	400668.Mmwyl1_3363	1.1e-65	208.0	COG2801@1|root,COG2801@2|Bacteria,1MVXQ@1224|Proteobacteria,1RPEW@1236|Gammaproteobacteria,1XJDJ@135619|Oceanospirillales	135619|Oceanospirillales	L	PFAM Integrase catalytic region	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve
k141_4266_2	525897.Dbac_0704	1.99e-224	626.0	COG0436@1|root,COG0436@2|Bacteria,1MWS8@1224|Proteobacteria,42NH6@68525|delta/epsilon subdivisions,2WJCV@28221|Deltaproteobacteria,2M8ZB@213115|Desulfovibrionales	28221|Deltaproteobacteria	H	Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate	dapL	GO:0003674,GO:0003824,GO:0008483,GO:0016740,GO:0016769	2.6.1.83	ko:K10206	ko00300,ko01100,ko01110,ko01130,ko01230,map00300,map01100,map01110,map01130,map01230	M00527	R07613	RC00006,RC01847	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
k141_2267_1	1304885.AUEY01000004_gene974	1.35e-170	489.0	COG1960@1|root,COG1960@2|Bacteria,1R15B@1224|Proteobacteria,42MUT@68525|delta/epsilon subdivisions,2WJ8T@28221|Deltaproteobacteria,2MI3E@213118|Desulfobacterales	28221|Deltaproteobacteria	C	acyl-CoA dehydrogenase	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M
k141_3641_1	443144.GM21_1566	6.5e-28	119.0	COG0834@1|root,COG4191@1|root,COG4936@1|root,COG0834@2|Bacteria,COG4191@2|Bacteria,COG4936@2|Bacteria,1RCM9@1224|Proteobacteria,42MC4@68525|delta/epsilon subdivisions,2WIZU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase A domain protein	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	GAF,HAMP,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,PocR,Response_reg,dCache_1,sCache_2
k141_316_1	13035.Dacsa_1583	9.19e-55	187.0	COG1090@1|root,COG1090@2|Bacteria,1G1NR@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM NAD dependent epimerase dehydratase family	-	-	-	ko:K07071	-	-	-	-	ko00000	-	-	-	DUF1731,Epimerase
k141_589_1	675813.VIB_000021	3.44e-272	761.0	COG0006@1|root,COG0006@2|Bacteria,1MUZS@1224|Proteobacteria,1RPQD@1236|Gammaproteobacteria,1XST4@135623|Vibrionales	135623|Vibrionales	E	COG0006 Xaa-Pro aminopeptidase	ampP	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Creatinase_N,Creatinase_N_2,Peptidase_M24,Peptidase_M24_C
k141_589_2	55601.VANGNB10_cII0722	8.74e-108	314.0	COG1309@1|root,COG1309@2|Bacteria,1MX72@1224|Proteobacteria,1RZBH@1236|Gammaproteobacteria,1XTMB@135623|Vibrionales	135623|Vibrionales	K	Repressor involved in choline regulation of the bet genes	betI	-	-	ko:K02167	-	-	-	-	ko00000,ko03000	-	-	-	TetR_C_6,TetR_N
k141_589_3	1187848.AJYQ01000156_gene3732	2.03e-276	765.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,1RMBQ@1236|Gammaproteobacteria,1XSW9@135623|Vibrionales	135623|Vibrionales	C	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the reversible oxidation of betaine aldehyde to the corresponding acid	betB	-	1.2.1.8	ko:K00130	ko00260,ko01100,map00260,map01100	M00555	R02565,R02566	RC00080	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
k141_589_4	223926.28809412	8.15e-165	468.0	COG2113@1|root,COG2113@2|Bacteria,1MVIG@1224|Proteobacteria,1RRNK@1236|Gammaproteobacteria,1XTWX@135623|Vibrionales	135623|Vibrionales	E	COG2113 ABC-type proline glycine betaine transport systems, periplasmic components	choX	-	-	ko:K02002	ko02010,map02010	M00208	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	OpuAC
k141_589_5	1188252.AJYK01000069_gene2176	5.41e-152	431.0	COG4176@1|root,COG4176@2|Bacteria,1MUM4@1224|Proteobacteria,1RPQS@1236|Gammaproteobacteria,1XSGK@135623|Vibrionales	135623|Vibrionales	P	COG4176 ABC-type proline glycine betaine transport system, permease component	choW	-	-	ko:K02001	ko02010,map02010	M00208	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	BPD_transp_1
k141_589_6	55601.VANGNB10_cII0727	5.58e-190	538.0	COG4175@1|root,COG4175@2|Bacteria,1MU86@1224|Proteobacteria,1RY4K@1236|Gammaproteobacteria,1Y2HJ@135623|Vibrionales	135623|Vibrionales	E	COG4175 ABC-type proline glycine betaine transport system, ATPase component	choV	-	3.6.3.32	ko:K02000	ko02010,map02010	M00208	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.12	-	-	ABC_tran
k141_3667_2	207954.MED92_01449	1.44e-31	119.0	COG1360@1|root,COG1360@2|Bacteria,1MU4S@1224|Proteobacteria,1S294@1236|Gammaproteobacteria,1XKCZ@135619|Oceanospirillales	135619|Oceanospirillales	N	Membrane MotB of proton-channel complex MotA/MotB	-	-	-	ko:K02557	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	MotB_plug,OmpA
k141_3256_1	909663.KI867150_gene1185	8.25e-17	85.1	COG0476@1|root,COG0476@2|Bacteria,1QUMS@1224|Proteobacteria,42P3N@68525|delta/epsilon subdivisions,2WKH0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	PFAM UBA THIF-type NAD FAD binding protein	-	-	-	-	-	-	-	-	-	-	-	-	ThiF
k141_3256_2	1120970.AUBZ01000003_gene199	2.15e-85	261.0	COG0265@1|root,COG0265@2|Bacteria,1R9ZV@1224|Proteobacteria,1S2AZ@1236|Gammaproteobacteria,466XQ@72275|Alteromonadaceae	1236|Gammaproteobacteria	O	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain	-	-	-	-	-	-	-	-	-	-	-	-	Trypsin_2
k141_3256_3	754436.JCM19237_3620	2e-69	239.0	COG0457@1|root,COG0457@2|Bacteria,1MXMD@1224|Proteobacteria,1RSI5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	ANAPC3,TPR_16,TPR_19,TPR_8
k141_3961_1	243277.VC_0304	3.84e-278	769.0	COG0248@1|root,COG0248@2|Bacteria,1MV35@1224|Proteobacteria,1RN3V@1236|Gammaproteobacteria,1XTYW@135623|Vibrionales	135623|Vibrionales	F	Catalyzes the conversion of pppGpp to ppGpp. Guanosine pentaphosphate (pppGpp) is a cytoplasmic signaling molecule which together with ppGpp controls the stringent response , an adaptive process that allows bacteria to respond to amino acid starvation, resulting in the coordinated regulation of numerous cellular activities	gppA	GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006793,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0008894,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0015949,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0034641,GO:0042594,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050896,GO:0051716,GO:0055086,GO:0071496,GO:0071704,GO:1901360	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	Ppx-GppA
k141_3961_2	1280001.BAOA01000011_gene4244	1.81e-151	441.0	COG0477@1|root,COG2814@2|Bacteria,1MVZI@1224|Proteobacteria,1RPBT@1236|Gammaproteobacteria,1XUPF@135623|Vibrionales	135623|Vibrionales	EGP	of the major facilitator superfamily	hcaT	-	-	ko:K05820	-	-	-	-	ko00000,ko02000	2.A.1.27	-	-	MFS_1_like
k141_3961_3	617140.AJZE01000046_gene591	6.62e-30	110.0	COG0757@1|root,COG0757@2|Bacteria,1RDDT@1224|Proteobacteria,1S3PX@1236|Gammaproteobacteria,1XWVA@135623|Vibrionales	135623|Vibrionales	E	Catalyzes a trans-dehydration via an enolate intermediate	aroQ	GO:0003674,GO:0003824,GO:0003855,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576	4.2.1.10	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03084	RC00848	ko00000,ko00001,ko00002,ko01000	-	-	-	DHquinase_II
k141_2861_1	1348635.BBJY01000011_gene1199	2.59e-246	700.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,1XU8V@135623|Vibrionales	135623|Vibrionales	NT	methyl-accepting chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal,dCache_1
k141_2861_2	1565129.JSFF01000008_gene2662	0.0	927.0	COG1292@1|root,COG1292@2|Bacteria,1MV0K@1224|Proteobacteria,1RP3E@1236|Gammaproteobacteria,2Q9YV@267890|Shewanellaceae	1236|Gammaproteobacteria	P	Belongs to the BCCT transporter (TC 2.A.15) family	butA	-	-	ko:K03451	-	-	-	-	ko00000	2.A.15	-	-	BCCT
k141_2861_4	1348635.BBJY01000015_gene727	4.98e-39	134.0	COG0735@1|root,COG0735@2|Bacteria,1QJWN@1224|Proteobacteria,1THYF@1236|Gammaproteobacteria,1XXWI@135623|Vibrionales	135623|Vibrionales	P	belongs to the Fur family	VV2111	-	-	-	-	-	-	-	-	-	-	-	-
k141_2861_5	1348635.BBJY01000015_gene728	2.16e-85	259.0	2CEWJ@1|root,32S0P@2|Bacteria,1N30H@1224|Proteobacteria,1S9KS@1236|Gammaproteobacteria,1XTGY@135623|Vibrionales	135623|Vibrionales	S	Protein of unknown function (DUF2982)	VV12961	-	-	-	-	-	-	-	-	-	-	-	DUF2982
k141_1978_1	1208321.D104_16475	7.3e-214	601.0	COG1253@1|root,COG1253@2|Bacteria,1MV3P@1224|Proteobacteria,1T1MS@1236|Gammaproteobacteria,1XND4@135619|Oceanospirillales	135619|Oceanospirillales	P	Transporter associated domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,DUF21
k141_2544_1	439235.Dalk_0572	2.68e-112	383.0	COG0745@1|root,COG2202@1|root,COG3829@1|root,COG4191@1|root,COG0745@2|Bacteria,COG2202@2|Bacteria,COG3829@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MC4@68525|delta/epsilon subdivisions,2WIZU@28221|Deltaproteobacteria,2MI2B@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg,dCache_1
k141_3962_2	489825.LYNGBM3L_46840	7.45e-17	83.6	COG3344@1|root,COG3344@2|Bacteria,1G065@1117|Cyanobacteria,1HADY@1150|Oscillatoriales	1117|Cyanobacteria	L	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	2.7.7.49	ko:K00986	-	-	-	-	ko00000,ko01000	-	-	-	GIIM,HNH,RVT_1,RVT_N
k141_3669_1	675817.VDA_001128	2.11e-107	324.0	COG3681@1|root,COG3681@2|Bacteria,1MW81@1224|Proteobacteria,1RP1R@1236|Gammaproteobacteria,1XUWS@135623|Vibrionales	135623|Vibrionales	S	Belongs to the UPF0597 family	-	-	-	-	-	-	-	-	-	-	-	-	SDH_alpha
k141_615_1	1304885.AUEY01000001_gene3252	0.0	1152.0	COG0085@1|root,COG0085@2|Bacteria,1MUC4@1224|Proteobacteria,43DMZ@68525|delta/epsilon subdivisions,2WIW5@28221|Deltaproteobacteria,2MI5C@213118|Desulfobacterales	28221|Deltaproteobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
k141_3963_1	1304885.AUEY01000013_gene3099	3.48e-164	470.0	COG0191@1|root,COG0191@2|Bacteria,1NMAK@1224|Proteobacteria,42NPW@68525|delta/epsilon subdivisions,2WIMN@28221|Deltaproteobacteria,2MHU7@213118|Desulfobacterales	28221|Deltaproteobacteria	G	aldolase class-II	-	-	4.1.2.13	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167,M00344,M00345	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	F_bP_aldolase
k141_3963_2	1408473.JHXO01000012_gene440	6.03e-10	58.5	COG2431@1|root,COG2431@2|Bacteria,4NMM0@976|Bacteroidetes,2FNT2@200643|Bacteroidia	976|Bacteroidetes	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	Lys_export
k141_1675_11	1236542.BALM01000004_gene2340	9.68e-131	382.0	COG0378@1|root,COG0378@2|Bacteria,1MVBD@1224|Proteobacteria,1RN9Y@1236|Gammaproteobacteria,2Q94R@267890|Shewanellaceae	1236|Gammaproteobacteria	KO	PFAM cobalamin synthesis protein P47K	hypB	GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0010467,GO:0016151,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0019538,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0051604,GO:0071704,GO:1901564	-	ko:K04652	-	-	-	-	ko00000,ko03110	-	-	-	cobW
k141_1675_12	316407.85675799	7.45e-19	82.4	COG0375@1|root,COG0375@2|Bacteria,1MZJH@1224|Proteobacteria,1S5WG@1236|Gammaproteobacteria,3XQYJ@561|Escherichia	1236|Gammaproteobacteria	S	Probably plays a role in a hydrogenase nickel cofactor insertion step	hypA	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009898,GO:0010467,GO:0016020,GO:0016151,GO:0019538,GO:0019897,GO:0019898,GO:0031234,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0046872,GO:0046914,GO:0051604,GO:0071704,GO:0071944,GO:0098552,GO:0098562,GO:1901564	-	ko:K04651	-	-	-	-	ko00000,ko03110	-	-	-	HypA
k141_1675_13	675817.VDA_000983	7.14e-159	454.0	COG0309@1|root,COG0309@2|Bacteria,1MVCC@1224|Proteobacteria,1RQBE@1236|Gammaproteobacteria,1XUS8@135623|Vibrionales	135623|Vibrionales	O	AIR synthase related protein, N-terminal domain	hypE	-	-	ko:K04655	-	-	-	-	ko00000	-	-	-	AIRS,AIRS_C
k141_1675_14	675817.VDA_000984	2.62e-195	550.0	COG0409@1|root,COG0409@2|Bacteria,1MU1F@1224|Proteobacteria,1RRTQ@1236|Gammaproteobacteria,1XVQU@135623|Vibrionales	135623|Vibrionales	O	Hydrogenase formation hypA family	hypD	-	-	ko:K04654	-	-	-	-	ko00000	-	-	-	HypD
k141_1675_15	675817.VDA_000985	8.58e-16	72.0	COG0298@1|root,COG0298@2|Bacteria	2|Bacteria	O	carbon dioxide binding	hypC	-	-	ko:K04653	-	-	-	-	ko00000	-	-	iHN637.CLJU_RS11355	HupF_HypC
k141_1675_16	314292.VAS14_14224	4.49e-253	729.0	COG0068@1|root,COG0068@2|Bacteria,1MVP8@1224|Proteobacteria,1RP08@1236|Gammaproteobacteria,1XVCE@135623|Vibrionales	135623|Vibrionales	O	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide	hypF	-	-	ko:K04656	-	-	-	-	ko00000	-	-	-	Acylphosphatase,Sua5_yciO_yrdC,zf-HYPF
k141_1675_17	1454202.PPBDW_100256___1	2.44e-108	322.0	COG1526@1|root,COG1526@2|Bacteria,1NRU0@1224|Proteobacteria,1RNFH@1236|Gammaproteobacteria,1XVCT@135623|Vibrionales	135623|Vibrionales	C	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH	-	-	-	-	-	-	-	-	-	-	-	-	FdhD-NarQ
k141_1675_18	1001530.BACE01000028_gene3886	2.56e-240	691.0	COG3604@1|root,COG3604@2|Bacteria,1QTT3@1224|Proteobacteria,1T1G7@1236|Gammaproteobacteria,1XW1P@135623|Vibrionales	135623|Vibrionales	KT	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	-	ko:K02584	ko02020,map02020	-	-	-	ko00000,ko00001,ko03000	-	-	-	GAF,GAF_2,HTH_8,Sigma54_activat
k141_4392_108	1284352.AOIG01000043_gene25	5.17e-45	168.0	COG3501@1|root,COG3501@2|Bacteria,1V3I5@1239|Firmicutes,4IH8T@91061|Bacilli,26SP3@186822|Paenibacillaceae	91061|Bacilli	T	Rhs element vgr protein	-	-	-	-	-	-	-	-	-	-	-	-	Colicin-DNase,Phage_GPD
k141_4392_109	1196322.A370_04886	0.000211	43.1	2DYN9@1|root,34AEQ@2|Bacteria,1VZ6G@1239|Firmicutes,24UZU@186801|Clostridia,36S8P@31979|Clostridiaceae	186801|Clostridia	S	Domain of unknown function (DUF4280)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4280
k141_4392_110	1211817.CCAT010000087_gene2337	4.52e-151	429.0	COG2185@1|root,COG2185@2|Bacteria,1TS6G@1239|Firmicutes,24AG8@186801|Clostridia,36UK1@31979|Clostridiaceae	186801|Clostridia	I	Dimerisation domain of d-ornithine 4,5-aminomutase	kamE	-	5.4.3.3	ko:K18011	ko00310,map00310	-	R02852,R03275	RC00719	ko00000,ko00001,ko01000	-	-	-	B12-binding,OAM_dimer
k141_4392_111	1321778.HMPREF1982_02716	1.89e-300	828.0	COG0274@1|root,COG0274@2|Bacteria,1TPA0@1239|Firmicutes,249YN@186801|Clostridia,267NE@186813|unclassified Clostridiales	186801|Clostridia	F	D-Lysine 5,6-aminomutase TIM-barrel domain of alpha subunit	kamD	-	5.4.3.3	ko:K01844	ko00310,map00310	-	R02852,R03275	RC00719	ko00000,ko00001,ko01000	-	-	-	Lys-AminoMut_A
k141_4392_112	1280692.AUJL01000033_gene504	5.29e-142	424.0	COG1193@1|root,COG1193@2|Bacteria,1TSBW@1239|Firmicutes,24814@186801|Clostridia,36FV5@31979|Clostridiaceae	186801|Clostridia	L	ATPase domain of DNA mismatch repair MUTS family	-	-	-	ko:K07456	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_V
k141_4392_113	1211817.CCAT010000087_gene2334	6.79e-106	320.0	2C3VR@1|root,2Z9AE@2|Bacteria,1UZNB@1239|Firmicutes,24D9F@186801|Clostridia,36FQA@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_4392_114	1499683.CCFF01000015_gene3348	3.2e-259	716.0	COG1509@1|root,COG1509@2|Bacteria,1TQQZ@1239|Firmicutes,249JV@186801|Clostridia,36E9A@31979|Clostridiaceae	186801|Clostridia	E	lysine 2,3-aminomutase YodO family protein	ablA	-	5.4.3.2	ko:K01843	ko00310,map00310	-	R00461	RC00303	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Fer4_14,LAM_C,Radical_SAM
k141_4392_115	857293.CAAU_1572	1.11e-182	516.0	COG0604@1|root,COG0604@2|Bacteria,1TQ4W@1239|Firmicutes,249C7@186801|Clostridia,36ER7@31979|Clostridiaceae	186801|Clostridia	C	alcohol dehydrogenase	kdd	-	1.4.1.11	ko:K18012	ko00310,map00310	-	R03349	RC00888	ko00000,ko00001,ko01000	-	-	-	ADH_zinc_N
k141_4392_116	1304284.L21TH_2531	1.14e-107	316.0	COG2057@1|root,COG2057@2|Bacteria,1TNY5@1239|Firmicutes,247ZM@186801|Clostridia,36GAR@31979|Clostridiaceae	186801|Clostridia	I	3-oxoacid CoA-transferase, B subunit	ctfB2	-	2.8.3.8,2.8.3.9	ko:K01035	ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020	-	R01179,R01359,R01365,R07832	RC00012,RC00014	ko00000,ko00001,ko01000	-	-	-	CoA_trans
k141_4392_117	857293.CAAU_1570	9.13e-104	305.0	COG1788@1|root,COG1788@2|Bacteria,1V21Q@1239|Firmicutes,25E61@186801|Clostridia,36UK0@31979|Clostridiaceae	186801|Clostridia	I	TIGRFAM 3-oxoacid CoA-transferase, A subunit	ctfA	-	2.8.3.8,2.8.3.9	ko:K01034	ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020	-	R01179,R01359,R01365,R07832	RC00012,RC00014	ko00000,ko00001,ko01000	-	-	-	CoA_trans
k141_4392_118	1499689.CCNN01000014_gene3166	4.86e-134	387.0	COG3246@1|root,COG3246@2|Bacteria,1TQNV@1239|Firmicutes,248TX@186801|Clostridia,36DPI@31979|Clostridiaceae	186801|Clostridia	S	beta-keto acid cleavage enzyme	kce	-	2.3.1.247	ko:K18013	ko00310,map00310	-	R10564	RC02728,RC03199	ko00000,ko00001,ko01000	-	-	-	BKACE
k141_4392_119	1042156.CXIVA_06670	3.41e-74	223.0	COG1607@1|root,COG1607@2|Bacteria,1V3ZQ@1239|Firmicutes,24HF8@186801|Clostridia,36IT9@31979|Clostridiaceae	186801|Clostridia	I	Thioesterase superfamily	kal	-	4.3.1.14	ko:K18014	ko00310,map00310	-	R03030	RC00833	ko00000,ko00001,ko01000	-	-	-	4HBT
k141_4392_121	1304284.L21TH_2530	5.27e-200	568.0	COG2031@1|root,COG2031@2|Bacteria,1TPCQ@1239|Firmicutes,247SN@186801|Clostridia,36FA0@31979|Clostridiaceae	186801|Clostridia	I	Short chain fatty acid transporter	-	-	-	ko:K02106	ko02020,map02020	-	-	-	ko00000,ko00001	2.A.73.1	-	-	SCFA_trans
k141_4392_122	1408422.JHYF01000001_gene2921	5.39e-71	216.0	COG1803@1|root,COG1803@2|Bacteria,1V3KQ@1239|Firmicutes,24FUQ@186801|Clostridia,36IPD@31979|Clostridiaceae	186801|Clostridia	G	methylglyoxal synthase	mgsA	-	4.2.3.3	ko:K01734	ko00640,ko01120,map00640,map01120	-	R01016	RC00424	ko00000,ko00001,ko01000	-	-	-	MGS
k141_4392_123	1286171.EAL2_c11570	1.92e-143	417.0	COG0772@1|root,COG0772@2|Bacteria,1TPGH@1239|Firmicutes,247WS@186801|Clostridia,25VRW@186806|Eubacteriaceae	186801|Clostridia	D	Belongs to the SEDS family	rodA	-	-	ko:K05837	-	-	-	-	ko00000,ko03036	-	-	-	FTSW_RODA_SPOVE
k141_4392_124	1286171.EAL2_c11560	4.06e-33	117.0	COG0851@1|root,COG0851@2|Bacteria,1VFST@1239|Firmicutes,24QT6@186801|Clostridia,25WUI@186806|Eubacteriaceae	186801|Clostridia	D	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell	minE	-	-	ko:K03608	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	MinE
k141_4392_125	1121324.CLIT_23c03370	8.24e-139	398.0	COG2894@1|root,COG2894@2|Bacteria,1TP6P@1239|Firmicutes,249BB@186801|Clostridia,25QSA@186804|Peptostreptococcaceae	186801|Clostridia	D	Cellulose biosynthesis protein BcsQ	minD	-	-	ko:K03609	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31,CbiA
k141_4392_126	1121324.CLIT_23c03360	3.6e-49	166.0	COG0850@1|root,COG0850@2|Bacteria,1VAPC@1239|Firmicutes,24MV1@186801|Clostridia,25TXB@186804|Peptostreptococcaceae	186801|Clostridia	D	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization	minC	-	-	ko:K03610	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	MinC_C
k141_4392_127	1121324.CLIT_23c03350	0.0	965.0	COG0768@1|root,COG0768@2|Bacteria,1TQHY@1239|Firmicutes,2480Z@186801|Clostridia,25QP8@186804|Peptostreptococcaceae	186801|Clostridia	M	Penicillin-binding protein, transpeptidase domain protein	mrdA	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	PBP_dimer,Transpeptidase
k141_4392_129	1511.CLOST_1394	3.05e-84	261.0	COG1792@1|root,COG1792@2|Bacteria,1TR1V@1239|Firmicutes,249M3@186801|Clostridia,25R0B@186804|Peptostreptococcaceae	186801|Clostridia	M	Involved in formation and maintenance of cell shape	mreC	-	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
k141_4392_130	293826.Amet_2290	1.59e-177	504.0	COG1077@1|root,COG1077@2|Bacteria,1TP51@1239|Firmicutes,247RG@186801|Clostridia,36DUP@31979|Clostridiaceae	186801|Clostridia	D	Cell shape determining protein, MreB Mrl family	mreB	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
k141_4392_131	272563.CD630_11440	1.95e-85	260.0	COG2003@1|root,COG2003@2|Bacteria,1TQ3K@1239|Firmicutes,2498Z@186801|Clostridia,25QVA@186804|Peptostreptococcaceae	186801|Clostridia	E	Belongs to the UPF0758 family	radC	-	-	ko:K03630	-	-	-	-	ko00000	-	-	-	RadC
k141_4392_132	1183377.Py04_0372	1.61e-44	153.0	COG0424@1|root,arCOG05007@2157|Archaea,2XZIF@28890|Euryarchaeota,243F5@183968|Thermococci	183968|Thermococci	D	Maf-like protein	maf	-	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
k141_4392_133	1121324.CLIT_23c03290	3.37e-142	409.0	COG1148@1|root,COG2878@1|root,COG1148@2|Bacteria,COG2878@2|Bacteria,1TQGD@1239|Firmicutes,24904@186801|Clostridia,25QGD@186804|Peptostreptococcaceae	186801|Clostridia	C	Electron transport complex	rnfB	-	-	ko:K03616	-	-	-	-	ko00000	-	-	-	FeS,Fer4,Fer4_13,Fer4_4,Fer4_9
k141_4392_134	1286171.EAL2_c11460	2.85e-102	299.0	COG4657@1|root,COG4657@2|Bacteria,1TS06@1239|Firmicutes,247UE@186801|Clostridia,25VXE@186806|Eubacteriaceae	186801|Clostridia	C	Part of a membrane complex involved in electron transport	rnfA	-	-	ko:K03617	-	-	-	-	ko00000	-	-	-	Rnf-Nqr
k141_4392_135	1511.CLOST_1399	3.46e-101	298.0	COG4660@1|root,COG4660@2|Bacteria,1TSE7@1239|Firmicutes,24972@186801|Clostridia,25QPE@186804|Peptostreptococcaceae	186801|Clostridia	C	Part of a membrane complex involved in electron transport	rnfE	-	-	ko:K03613	-	-	-	-	ko00000	-	-	iHN637.CLJU_RS05585	Rnf-Nqr
k141_4392_136	1121324.CLIT_23c03260	7.41e-63	199.0	COG4659@1|root,COG4659@2|Bacteria,1V7R1@1239|Firmicutes,24JVM@186801|Clostridia	186801|Clostridia	C	Part of a membrane complex involved in electron transport	rnfG	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K03612	-	-	-	-	ko00000	-	-	-	FMN_bind
k141_4392_137	1121324.CLIT_23c03250	5.16e-169	478.0	COG4658@1|root,COG4658@2|Bacteria,1TQAY@1239|Firmicutes,247TM@186801|Clostridia	186801|Clostridia	C	Part of a membrane complex involved in electron transport	rnfD	-	-	ko:K03614	-	-	-	-	ko00000	-	-	-	NQR2_RnfD_RnfE
k141_4392_138	1121324.CLIT_23c03240	7.23e-214	602.0	COG4656@1|root,COG4656@2|Bacteria,1TPCC@1239|Firmicutes,24805@186801|Clostridia,25QF7@186804|Peptostreptococcaceae	186801|Clostridia	C	Part of a membrane complex involved in electron transport	rnfC	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K03615	-	-	-	-	ko00000	-	-	-	Complex1_51K,Fer4_10,RnfC_N,SLBB
k141_4392_140	1122173.AXVL01000057_gene625	2.18e-34	130.0	COG0791@1|root,COG0791@2|Bacteria,37AR2@32066|Fusobacteria	32066|Fusobacteria	M	NlpC P60 family protein	-	-	-	-	-	-	-	-	-	-	-	-	NLPC_P60
k141_4392_142	994573.T472_0206885	2.29e-05	55.8	COG0747@1|root,COG0747@2|Bacteria,1TQ6S@1239|Firmicutes,248A3@186801|Clostridia,36WU1@31979|Clostridiaceae	186801|Clostridia	E	Extracellular solute-binding protein, family 5	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
k141_4392_143	489825.LYNGBM3L_42030	1.83e-21	98.6	COG0457@1|root,COG0741@1|root,COG0457@2|Bacteria,COG0741@2|Bacteria,1G4F1@1117|Cyanobacteria,1H97X@1150|Oscillatoriales	1117|Cyanobacteria	M	Transglycosylase SLT domain	-	-	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	SLT,TPR_6
k141_4392_144	1110697.NCAST_26_01120	1.54e-19	93.2	COG0237@1|root,COG0237@2|Bacteria,2GN96@201174|Actinobacteria,4FUXF@85025|Nocardiaceae	201174|Actinobacteria	H	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A	coaE	GO:0000166,GO:0001882,GO:0001884,GO:0002135,GO:0003674,GO:0003824,GO:0004140,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0018130,GO:0019103,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032549,GO:0032551,GO:0032552,GO:0032553,GO:0032554,GO:0032557,GO:0032558,GO:0032564,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.7.1.24	ko:K00859	ko00770,ko01100,map00770,map01100	M00120	R00130	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CoaE,GrpB
k141_4392_145	1121324.CLIT_11c00670	0.0	1036.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1TPKJ@1239|Firmicutes,248NG@186801|Clostridia,25QCY@186804|Peptostreptococcaceae	186801|Clostridia	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
k141_4392_147	293826.Amet_3126	6.9e-10	68.9	COG1196@1|root,COG1196@2|Bacteria,1UIE6@1239|Firmicutes,25EJB@186801|Clostridia	186801|Clostridia	D	Domain of unknown function (DUF4349)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4349,zf-HC2
k141_4392_148	1121930.AQXG01000003_gene2697	3.89e-21	92.8	COG1595@1|root,COG1595@2|Bacteria,4NQE0@976|Bacteroidetes	976|Bacteroidetes	K	Belongs to the sigma-70 factor family. ECF subfamily	rpoE	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
k141_4392_149	1121324.CLIT_11c00580	2.71e-141	416.0	COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,247VG@186801|Clostridia,25QXW@186804|Peptostreptococcaceae	186801|Clostridia	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein	phoR2	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4,sCache_like
k141_4392_150	1511.CLOST_1888	5.01e-108	317.0	COG0745@1|root,COG0745@2|Bacteria,1TPWS@1239|Firmicutes,25AZ2@186801|Clostridia,25QP7@186804|Peptostreptococcaceae	186801|Clostridia	K	response regulator	phoP	-	-	ko:K02483,ko:K07658,ko:K07668	ko02020,map02020	M00434,M00459	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
k141_4392_151	1354300.AUQY01000002_gene909	1.42e-55	178.0	COG1327@1|root,COG1327@2|Bacteria,1V3JA@1239|Firmicutes,24HFT@186801|Clostridia,22HHT@1570339|Peptoniphilaceae	186801|Clostridia	K	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes	nrdR	-	-	ko:K07738	-	-	-	-	ko00000,ko03000	-	-	-	ATP-cone
k141_4392_152	1121324.CLIT_11c00540	8.69e-173	492.0	COG0206@1|root,COG0206@2|Bacteria,1TP6W@1239|Firmicutes,247Z5@186801|Clostridia,25QCR@186804|Peptostreptococcaceae	186801|Clostridia	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
k141_4392_153	1121324.CLIT_11c00530	1.04e-44	148.0	COG3856@1|root,COG3856@2|Bacteria,1VA6N@1239|Firmicutes,24N58@186801|Clostridia,25TFI@186804|Peptostreptococcaceae	186801|Clostridia	S	Protein of unknown function (DUF1290)	sbp	-	-	-	-	-	-	-	-	-	-	-	DUF1290
k141_4392_154	1151292.QEW_3193	1.09e-45	159.0	COG3879@1|root,COG3879@2|Bacteria,1V0FG@1239|Firmicutes,24DRC@186801|Clostridia,25SZ2@186804|Peptostreptococcaceae	186801|Clostridia	S	Bacterial protein of unknown function (DUF881)	-	-	-	-	-	-	-	-	-	-	-	-	DUF881
k141_4392_155	1121324.CLIT_11c00510	1.61e-72	228.0	COG3879@1|root,COG3879@2|Bacteria,1V66C@1239|Firmicutes,2492Y@186801|Clostridia,25TEP@186804|Peptostreptococcaceae	186801|Clostridia	S	Bacterial protein of unknown function (DUF881)	-	-	-	-	-	-	-	-	-	-	-	-	DUF881
k141_4392_156	1121324.CLIT_11c00500	1.16e-55	186.0	COG1589@1|root,COG1589@2|Bacteria,1VEMW@1239|Firmicutes,24QKM@186801|Clostridia	186801|Clostridia	D	Cell division protein FtsQ	ftsQ	-	-	ko:K03589	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036	-	-	-	FtsQ,POTRA_1
k141_4392_157	596329.HMPREF0631_1844	5.39e-111	335.0	COG0707@1|root,COG0707@2|Bacteria,1TQFT@1239|Firmicutes,248IA@186801|Clostridia,25R4M@186804|Peptostreptococcaceae	186801|Clostridia	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
k141_4392_158	1408823.AXUS01000018_gene3097	3.85e-120	361.0	COG0772@1|root,COG0772@2|Bacteria,1TPT7@1239|Firmicutes,24894@186801|Clostridia,25QJI@186804|Peptostreptococcaceae	186801|Clostridia	D	Belongs to the SEDS family	ftsW	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
k141_4392_159	1391646.AVSU01000092_gene398	2.59e-156	457.0	COG0771@1|root,COG0771@2|Bacteria,1TQ3P@1239|Firmicutes,248GS@186801|Clostridia,25QXT@186804|Peptostreptococcaceae	186801|Clostridia	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_C,Mur_ligase_M
k141_4392_160	1286171.EAL2_c10450	2.85e-104	315.0	COG0472@1|root,COG0472@2|Bacteria,1TP8W@1239|Firmicutes,247S7@186801|Clostridia,25V83@186806|Eubacteriaceae	186801|Clostridia	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	-	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	-	Glycos_transf_4,MraY_sig1
k141_4392_161	1476973.JMMB01000007_gene857	1.34e-151	446.0	COG0770@1|root,COG0770@2|Bacteria,1VT78@1239|Firmicutes,25100@186801|Clostridia,25QJG@186804|Peptostreptococcaceae	186801|Clostridia	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
k141_4392_162	1304284.L21TH_0611	5.35e-135	406.0	COG0769@1|root,COG0769@2|Bacteria,1TPQE@1239|Firmicutes,248Q4@186801|Clostridia,36DF8@31979|Clostridiaceae	186801|Clostridia	M	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	-	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
k141_4392_163	1286171.EAL2_c10420	5.28e-231	669.0	COG0768@1|root,COG0768@2|Bacteria,1TP93@1239|Firmicutes,248KB@186801|Clostridia,25V2F@186806|Eubacteriaceae	186801|Clostridia	M	Penicillin-binding protein, transpeptidase domain protein	spoVD	-	3.4.16.4	ko:K03587,ko:K08384	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PASTA,PBP_dimer,Transpeptidase
k141_4392_164	1121289.JHVL01000030_gene402	8.28e-09	58.2	2FKXC@1|root,34CHK@2|Bacteria,1VIXH@1239|Firmicutes,24TRI@186801|Clostridia	186801|Clostridia	S	Septum formation initiator	-	-	-	-	-	-	-	-	-	-	-	-	DivIC
k141_4392_165	1121324.CLIT_11c00410	8.64e-168	475.0	COG0275@1|root,COG0275@2|Bacteria,1TNZV@1239|Firmicutes,248B5@186801|Clostridia,25QND@186804|Peptostreptococcaceae	186801|Clostridia	J	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH	-	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
k141_4392_166	1121324.CLIT_11c00400	1.29e-121	353.0	COG0682@1|root,COG0682@2|Bacteria,1TPAK@1239|Firmicutes,24APG@186801|Clostridia,25QZI@186804|Peptostreptococcaceae	186801|Clostridia	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
k141_4392_167	1121324.CLIT_11c00390	1.01e-216	608.0	COG0612@1|root,COG0612@2|Bacteria,1TP5I@1239|Firmicutes,248HT@186801|Clostridia,25R6R@186804|Peptostreptococcaceae	186801|Clostridia	S	Peptidase M16 inactive domain protein	ymfH	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
k141_4392_168	1121324.CLIT_11c00380	1.27e-145	427.0	COG0612@1|root,COG0612@2|Bacteria,1TPN6@1239|Firmicutes,248J8@186801|Clostridia,25R2M@186804|Peptostreptococcaceae	186801|Clostridia	S	Peptidase M16 inactive domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16_C
k141_4392_169	596329.HMPREF0631_1854	4.2e-179	508.0	COG0012@1|root,COG0012@2|Bacteria,1TPRK@1239|Firmicutes,2482Z@186801|Clostridia,25QQJ@186804|Peptostreptococcaceae	186801|Clostridia	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
k141_4394_1	264462.Bd3688	7.52e-08	52.8	COG0583@1|root,COG0583@2|Bacteria,1MU2E@1224|Proteobacteria,42T5W@68525|delta/epsilon subdivisions,2MTTD@213481|Bdellovibrionales,2WPVR@28221|Deltaproteobacteria	213481|Bdellovibrionales	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
k141_4394_2	717774.Marme_0128	1.94e-42	148.0	COG2370@1|root,COG2370@2|Bacteria,1N08F@1224|Proteobacteria,1SA2T@1236|Gammaproteobacteria,1XKVA@135619|Oceanospirillales	135619|Oceanospirillales	O	HupE / UreJ protein	-	-	-	ko:K03192	-	-	-	-	ko00000	-	-	-	HupE_UreJ
k141_4394_3	595494.Tola_1852	4.23e-154	444.0	COG2220@1|root,COG2220@2|Bacteria,1MV20@1224|Proteobacteria,1RN4Z@1236|Gammaproteobacteria,1Y53W@135624|Aeromonadales	135624|Aeromonadales	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
k141_3355_4	1348635.BBJY01000002_gene3467	1.72e-300	834.0	COG1167@1|root,COG1167@2|Bacteria,1MVGT@1224|Proteobacteria,1RPFK@1236|Gammaproteobacteria,1XTBA@135623|Vibrionales	135623|Vibrionales	K	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs	-	-	-	ko:K00375	-	-	-	-	ko00000,ko03000	-	-	-	Aminotran_1_2,GntR
k141_3355_5	1123250.KB908394_gene1908	1.3e-222	625.0	COG0160@1|root,COG0160@2|Bacteria,1VS6F@1239|Firmicutes,4H2ZF@909932|Negativicutes	909932|Negativicutes	E	Aminotransferase class-III	-	-	2.6.1.19,2.6.1.22	ko:K07250	ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120	M00027	R00908,R01648,R04188	RC00006,RC00062,RC00160	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
k141_3355_6	1116375.VEJY3_22286	1.59e-283	781.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,1RMBQ@1236|Gammaproteobacteria,1XSW9@135623|Vibrionales	135623|Vibrionales	C	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the reversible oxidation of betaine aldehyde to the corresponding acid	gabD	-	1.2.1.16,1.2.1.20,1.2.1.79	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	M00027	R00713,R00714,R02401	RC00080	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
k141_4395_1	1304885.AUEY01000022_gene3413	2.12e-70	235.0	COG5000@1|root,COG5000@2|Bacteria,1MWKZ@1224|Proteobacteria,42MCN@68525|delta/epsilon subdivisions,2WIYA@28221|Deltaproteobacteria,2MHZN@213118|Desulfobacterales	28221|Deltaproteobacteria	T	histidine kinase HAMP region domain protein	ntrY	-	2.7.13.3	ko:K13598	ko02020,map02020	M00498	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4
k141_4395_2	1304885.AUEY01000022_gene3410	1.58e-135	404.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WJ88@28221|Deltaproteobacteria,2MI3G@213118|Desulfobacterales	28221|Deltaproteobacteria	T	response regulator receiver	ntrX	-	-	ko:K13599	ko02020,map02020	M00498	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
k141_4395_3	1089552.KI911559_gene3309	0.000967	41.2	COG0742@1|root,COG0742@2|Bacteria,1MXKW@1224|Proteobacteria,2U70Y@28211|Alphaproteobacteria,2JSVT@204441|Rhodospirillales	204441|Rhodospirillales	L	Conserved hypothetical protein 95	rsmD	-	2.1.1.171	ko:K08316	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Cons_hypoth95
k141_4396_1	1499967.BAYZ01000062_gene6036	5.45e-54	190.0	COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria	2|Bacteria	S	CHAT domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_12,TPR_16,TPR_7,TPR_8
k141_4398_1	78344.BIGA_0639	1.87e-50	180.0	COG1123@1|root,COG4172@2|Bacteria,2H3HY@201174|Actinobacteria,4CYU0@85004|Bifidobacteriales	201174|Actinobacteria	P	Belongs to the ABC transporter superfamily	oppD	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	ko:K02031,ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
k141_4398_2	1265505.ATUG01000003_gene675	8.9e-80	244.0	COG1173@1|root,COG1173@2|Bacteria,1MW3R@1224|Proteobacteria,43AQ5@68525|delta/epsilon subdivisions,2X63Y@28221|Deltaproteobacteria	28221|Deltaproteobacteria	EP	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
k141_5347_1	536227.CcarbDRAFT_2018	1.05e-37	134.0	COG0703@1|root,COG0703@2|Bacteria,1VA6Z@1239|Firmicutes,24MQY@186801|Clostridia,36JKN@31979|Clostridiaceae	186801|Clostridia	F	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate	aroK	-	2.7.1.71	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	SKI
k141_5347_2	941824.TCEL_00268	8.08e-53	171.0	COG0757@1|root,COG0757@2|Bacteria,1V6E8@1239|Firmicutes,24JBK@186801|Clostridia,36JJ0@31979|Clostridiaceae	186801|Clostridia	E	Catalyzes a trans-dehydration via an enolate intermediate	aroQ	-	4.2.1.10	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03084	RC00848	ko00000,ko00001,ko00002,ko01000	-	-	-	DHquinase_II
k141_5347_3	1304284.L21TH_1988	7.22e-50	167.0	COG2431@1|root,COG2431@2|Bacteria,1V44M@1239|Firmicutes,24I3B@186801|Clostridia,36ID9@31979|Clostridiaceae	186801|Clostridia	S	Lysine exporter LysO	-	-	-	-	-	-	-	-	-	-	-	-	Lys_export
k141_5347_5	1347392.CCEZ01000049_gene1303	4.5e-155	466.0	COG3829@1|root,COG3829@2|Bacteria,1TP0E@1239|Firmicutes,247MB@186801|Clostridia,36FNE@31979|Clostridiaceae	186801|Clostridia	KT	Sigma-54 interaction domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,PAS,PAS_9,Sigma54_activat
k141_5347_6	1408422.JHYF01000014_gene261	1.76e-150	441.0	COG0019@1|root,COG0019@2|Bacteria,1TPE9@1239|Firmicutes,247X7@186801|Clostridia,36FIT@31979|Clostridiaceae	186801|Clostridia	E	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine	lysA	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
k141_5347_7	293826.Amet_1114	6.48e-47	159.0	2BYWB@1|root,331N7@2|Bacteria,1VC73@1239|Firmicutes,24NV6@186801|Clostridia	186801|Clostridia	S	Protein of unknown function (DUF3793)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3793
k141_5347_8	1122172.KB890259_gene1292	3.79e-74	228.0	COG0311@1|root,COG0311@2|Bacteria,37A0Y@32066|Fusobacteria	32066|Fusobacteria	H	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS	pdxT	-	4.3.3.6	ko:K08681	ko00750,map00750	-	R07456	RC00010,RC01783,RC03043	ko00000,ko00001,ko01000	-	-	-	SNO
k141_5347_9	1286171.EAL2_808p06350	1.37e-148	425.0	COG0214@1|root,COG0214@2|Bacteria,1TPSZ@1239|Firmicutes,248C1@186801|Clostridia,25VF3@186806|Eubacteriaceae	186801|Clostridia	H	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively	pdxS	-	4.3.3.6	ko:K06215	ko00750,map00750	-	R07456	RC00010,RC01783,RC03043	ko00000,ko00001,ko01000	-	-	-	SOR_SNZ
k141_5347_11	431943.CKL_2330	3.41e-211	593.0	COG1160@1|root,COG1160@2|Bacteria,1UI84@1239|Firmicutes,25EDI@186801|Clostridia,36UM4@31979|Clostridiaceae	186801|Clostridia	S	small GTP-binding protein	hydF	-	-	-	-	-	-	-	-	-	-	-	MMR_HSR1
k141_5347_12	431943.CKL_2331	1.78e-214	606.0	COG1027@1|root,COG1027@2|Bacteria,1TP3U@1239|Firmicutes,2483Z@186801|Clostridia,36DQI@31979|Clostridiaceae	186801|Clostridia	E	Aspartate ammonia-lyase	ansB	-	4.3.1.1	ko:K01744	ko00250,ko01100,map00250,map01100	-	R00490	RC00316,RC02799	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS20875	FumaraseC_C,Lyase_1
k141_5347_13	1294142.CINTURNW_2858	1.8e-07	51.2	2E97I@1|root,333G1@2|Bacteria,1VGBC@1239|Firmicutes,24PN9@186801|Clostridia,36M64@31979|Clostridiaceae	186801|Clostridia	S	Protein of unknown function (DUF1292)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1292
k141_2757_45	588581.Cpap_1767	3.94e-202	610.0	COG1020@1|root,COG1020@2|Bacteria,1V004@1239|Firmicutes,24E28@186801|Clostridia,3WNET@541000|Ruminococcaceae	186801|Clostridia	Q	Phosphopantetheine attachment site	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,PP-binding
k141_2757_46	1298920.KI911353_gene840	6.33e-64	207.0	COG3208@1|root,COG3208@2|Bacteria,1V5K3@1239|Firmicutes,24HA1@186801|Clostridia,222ZW@1506553|Lachnoclostridium	186801|Clostridia	Q	Thioesterase domain	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase,Thioesterase
k141_2757_47	324831.LGAS_0884	4.4e-32	129.0	COG4974@1|root,COG4974@2|Bacteria,1TQRG@1239|Firmicutes,4HAEX@91061|Bacilli,3F3V9@33958|Lactobacillaceae	91061|Bacilli	D	recombinase XerD	xerD	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
k141_2757_48	1292035.H476_1062	1.46e-232	648.0	COG4100@1|root,COG4100@2|Bacteria,1TQ88@1239|Firmicutes,247Y4@186801|Clostridia,25R6P@186804|Peptostreptococcaceae	186801|Clostridia	P	Aluminum resistance protein	ynbB	-	-	-	-	-	-	-	-	-	-	-	Met_gamma_lyase
k141_2757_50	1121324.CLIT_11c02820	8.66e-292	816.0	COG0174@1|root,COG0174@2|Bacteria,1TNZA@1239|Firmicutes,2489S@186801|Clostridia	186801|Clostridia	E	glutamine synthetase	glnA	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C
k141_2757_51	521460.Athe_1391	2.05e-08	55.5	COG1388@1|root,COG1388@2|Bacteria	2|Bacteria	M	LysM domain	-	-	3.5.1.28	ko:K01447,ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3,Glyco_hydro_25,LysM
k141_2757_52	1391646.AVSU01000151_gene2689	2.27e-77	238.0	COG1974@1|root,COG1974@2|Bacteria,1TQ3H@1239|Firmicutes,24AXJ@186801|Clostridia,25RMC@186804|Peptostreptococcaceae	186801|Clostridia	K	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair	lexA	-	3.4.21.88	ko:K01356	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	LexA_DNA_bind,Peptidase_S24
k141_2757_54	1230342.CTM_26103	2.61e-114	333.0	COG1515@1|root,COG1515@2|Bacteria,1V1CJ@1239|Firmicutes,24C24@186801|Clostridia,36HC9@31979|Clostridiaceae	186801|Clostridia	L	DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA	nfi	-	3.1.21.7	ko:K05982	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	Endonuclease_5
k141_2757_56	620914.JH621251_gene2376	2.46e-22	102.0	2ETUU@1|root,33MC2@2|Bacteria,4NZ8U@976|Bacteroidetes,1I9XH@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_2757_57	536232.CLM_0764	1.09e-135	440.0	COG1816@1|root,COG1816@2|Bacteria,1UHMY@1239|Firmicutes,24D5F@186801|Clostridia,36QBX@31979|Clostridiaceae	186801|Clostridia	F	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism	-	-	-	-	-	-	-	-	-	-	-	-	A_deaminase
k141_2757_58	445335.CBN_0698	7.38e-46	189.0	2E8YT@1|root,3338E@2|Bacteria,1VFTE@1239|Firmicutes,24M7U@186801|Clostridia,36JWB@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_2757_59	37659.JNLN01000001_gene1717	1.76e-53	208.0	COG1337@1|root,COG1337@2|Bacteria,1UZIC@1239|Firmicutes,24AP1@186801|Clostridia,36M4Q@31979|Clostridiaceae	186801|Clostridia	L	RAMP superfamily	-	-	-	-	-	-	-	-	-	-	-	-	RAMPs
k141_2757_61	1410653.JHVC01000034_gene3746	3.09e-98	328.0	COG1337@1|root,COG1337@2|Bacteria,1UZIC@1239|Firmicutes,24AP1@186801|Clostridia,36M4Q@31979|Clostridiaceae	186801|Clostridia	L	RAMP superfamily	-	-	-	-	-	-	-	-	-	-	-	-	RAMPs
k141_2757_63	479436.Vpar_1814	1.43e-12	78.6	COG1337@1|root,COG1337@2|Bacteria,1V6T4@1239|Firmicutes,4H4BJ@909932|Negativicutes	909932|Negativicutes	L	CRISPR-associated RAMP protein	-	-	-	-	-	-	-	-	-	-	-	-	RAMPs
k141_2757_64	1410653.JHVC01000034_gene3743	4.96e-67	246.0	COG1337@1|root,COG1337@2|Bacteria,1VB9Y@1239|Firmicutes,24KU1@186801|Clostridia,36KKG@31979|Clostridiaceae	186801|Clostridia	L	RAMP superfamily	-	-	-	ko:K19134	-	-	-	-	ko00000,ko02048	-	-	-	RAMPs
k141_2757_65	1410653.JHVC01000034_gene3742	1.27e-20	105.0	COG1353@1|root,COG1353@2|Bacteria,1UZM3@1239|Firmicutes,24KWD@186801|Clostridia,36K3C@31979|Clostridiaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_2757_66	1121447.JONL01000002_gene1797	4.23e-56	186.0	COG0692@1|root,COG0692@2|Bacteria,1MV80@1224|Proteobacteria,42MYK@68525|delta/epsilon subdivisions,2WN3P@28221|Deltaproteobacteria,2MBQ1@213115|Desulfovibrionales	28221|Deltaproteobacteria	L	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine	ung	-	3.2.2.27	ko:K03648	ko03410,ko05340,map03410,map05340	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
k141_2757_68	717606.PaecuDRAFT_3460	1.71e-88	285.0	COG0464@1|root,COG0464@2|Bacteria,1UBVM@1239|Firmicutes,4ITDB@91061|Bacilli,277CY@186822|Paenibacillaceae	91061|Bacilli	O	ATPase family associated with various cellular activities (AAA)	-	-	-	-	-	-	-	-	-	-	-	-	AAA
k141_2757_69	573061.Clocel_1667	2.17e-99	296.0	COG2454@1|root,COG2454@2|Bacteria,1V42I@1239|Firmicutes,24BAF@186801|Clostridia,36FFD@31979|Clostridiaceae	186801|Clostridia	S	Protein of unknown function (DUF434)	-	-	-	-	-	-	-	-	-	-	-	-	DUF434
k141_2757_71	446468.Ndas_1772	1.62e-138	407.0	COG0688@1|root,COG0688@2|Bacteria,2IBDY@201174|Actinobacteria	201174|Actinobacteria	I	Belongs to the phosphatidylserine decarboxylase family	-	-	4.1.1.65	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	M00093	R02055	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	PSDC,PS_Dcarbxylase
k141_2757_72	439235.Dalk_1621	9.49e-88	297.0	COG0076@1|root,COG2939@1|root,COG0076@2|Bacteria,COG2939@2|Bacteria,1Q16U@1224|Proteobacteria,42YZ1@68525|delta/epsilon subdivisions,2WUCA@28221|Deltaproteobacteria,2MP6I@213118|Desulfobacterales	28221|Deltaproteobacteria	E	PFAM Peptidase S10, serine carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_2757_76	398512.JQKC01000010_gene179	4.46e-14	83.2	COG3501@1|root,COG3501@2|Bacteria,1TSS0@1239|Firmicutes,25BBM@186801|Clostridia	186801|Clostridia	S	Rhs element vgr protein	-	-	-	-	-	-	-	-	-	-	-	-	Phage_GPD
k141_2757_78	398512.JQKC01000010_gene179	4.13e-56	208.0	COG3501@1|root,COG3501@2|Bacteria,1TSS0@1239|Firmicutes,25BBM@186801|Clostridia	186801|Clostridia	S	Rhs element vgr protein	-	-	-	-	-	-	-	-	-	-	-	-	Phage_GPD
k141_2757_79	1122921.KB898188_gene5	7.86e-22	95.1	2EE7B@1|root,3381W@2|Bacteria,1VAIC@1239|Firmicutes,4I80S@91061|Bacilli,26YGS@186822|Paenibacillaceae	91061|Bacilli	S	Domain of unknown function (DUF4280)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4280
k141_2757_82	398512.JQKC01000008_gene816	5.01e-109	338.0	COG3501@1|root,COG3501@2|Bacteria,1V043@1239|Firmicutes,248CZ@186801|Clostridia,3WNKD@541000|Ruminococcaceae	186801|Clostridia	S	Rhs element vgr protein	gpP	-	-	-	-	-	-	-	-	-	-	-	Phage_GPD
k141_2757_83	1410653.JHVC01000008_gene3074	1.32e-42	149.0	2EFPB@1|root,339FB@2|Bacteria,1V5BB@1239|Firmicutes,24BIN@186801|Clostridia,36HDD@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_2757_84	1345695.CLSA_c08120	1.43e-53	181.0	28N3U@1|root,2ZB9G@2|Bacteria,1V09T@1239|Firmicutes,2493C@186801|Clostridia,36GU6@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_2757_85	1196322.A370_05277	1.13e-168	520.0	COG0443@1|root,COG0443@2|Bacteria,1TT0Z@1239|Firmicutes,24AG5@186801|Clostridia,36EUB@31979|Clostridiaceae	186801|Clostridia	O	Heat shock 70 kDa protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_2757_86	641107.CDLVIII_1217	2.59e-63	204.0	28N97@1|root,2ZBD9@2|Bacteria,1UYY7@1239|Firmicutes,24MD6@186801|Clostridia,36GUV@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_2757_87	641107.CDLVIII_1216	4.48e-83	268.0	28ISJ@1|root,2Z8RQ@2|Bacteria,1TRGC@1239|Firmicutes,24CC6@186801|Clostridia,36EES@31979|Clostridiaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_2757_88	1410653.JHVC01000008_gene3080	1.14e-112	354.0	COG0631@1|root,COG0631@2|Bacteria,1TQWN@1239|Firmicutes,247KV@186801|Clostridia,36F98@31979|Clostridiaceae	186801|Clostridia	T	Serine/threonine phosphatases, family 2C, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIE
k141_2757_89	1449050.JNLE01000003_gene1186	1.54e-54	185.0	COG0631@1|root,COG0631@2|Bacteria,1V094@1239|Firmicutes,24N9G@186801|Clostridia,36F42@31979|Clostridiaceae	186801|Clostridia	T	Serine/threonine phosphatases, family 2C, catalytic domain	-	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C,PP2C_2,SpoIIE
k141_2757_90	1415774.U728_285	3.24e-82	247.0	COG1716@1|root,COG1716@2|Bacteria,1UZ57@1239|Firmicutes,24PC6@186801|Clostridia,36GM9@31979|Clostridiaceae	186801|Clostridia	T	FHA domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA,Yop-YscD_cpl
k141_2757_91	397291.C804_06508	7.95e-25	102.0	COG1716@1|root,COG1716@2|Bacteria,1VFJ4@1239|Firmicutes,24Q0H@186801|Clostridia,27PDZ@186928|unclassified Lachnospiraceae	186801|Clostridia	T	Forkhead associated domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA
k141_2757_92	1163389.OOM_0477	5.82e-15	78.2	COG0484@1|root,COG0484@2|Bacteria,1MVMS@1224|Proteobacteria,1RNHY@1236|Gammaproteobacteria,45ZTV@72273|Thiotrichales	72273|Thiotrichales	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
k141_2757_93	290402.Cbei_4405	2.73e-72	219.0	2AGPY@1|root,316XK@2|Bacteria,1V8P2@1239|Firmicutes,25DTK@186801|Clostridia,36I5F@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_2757_94	1410653.JHVC01000008_gene3086	5.75e-74	224.0	2AGPY@1|root,316XK@2|Bacteria,1V241@1239|Firmicutes,25DTM@186801|Clostridia,36I8A@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_2757_95	1410653.JHVC01000008_gene3087	0.0	1050.0	2C1IS@1|root,2Z86T@2|Bacteria,1TQRA@1239|Firmicutes,247QX@186801|Clostridia,36FTF@31979|Clostridiaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_2757_98	318464.IO99_04310	1.21e-193	541.0	28H6R@1|root,2Z7J3@2|Bacteria,1TQ2I@1239|Firmicutes,247QF@186801|Clostridia,36EPD@31979|Clostridiaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_2757_99	1120998.AUFC01000001_gene1735	1.18e-109	335.0	COG3325@1|root,COG3858@1|root,COG3325@2|Bacteria,COG3858@2|Bacteria,1VF50@1239|Firmicutes,24KR5@186801|Clostridia	186801|Clostridia	G	Glyco_18	-	-	-	-	-	-	-	-	-	-	-	-	Cu_amine_oxidN1,Glyco_hydro_18
k141_2757_101	1511.CLOST_1664	7.11e-125	366.0	COG1242@1|root,COG1242@2|Bacteria,1TQ57@1239|Firmicutes,247U3@186801|Clostridia,25QUN@186804|Peptostreptococcaceae	186801|Clostridia	S	radical SAM protein, TIGR01212 family	ytqA	-	-	ko:K07139	-	-	-	-	ko00000	-	-	-	Radical_SAM,Radical_SAM_C
k141_2757_102	1121324.CLIT_23c04960	6.74e-247	689.0	COG0015@1|root,COG0015@2|Bacteria,1TPMM@1239|Firmicutes,2485N@186801|Clostridia,25QVH@186804|Peptostreptococcaceae	186801|Clostridia	F	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	purB	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ADSL_C,Lyase_1
k141_2757_105	1005048.CFU_0008	4.45e-188	541.0	COG3344@1|root,COG3344@2|Bacteria,1R83H@1224|Proteobacteria	1224|Proteobacteria	L	RNA-directed DNA polymerase	-	-	-	-	-	-	-	-	-	-	-	-	RVT_1
k141_2757_106	37659.JNLN01000001_gene1338	1.43e-102	308.0	COG2017@1|root,COG2017@2|Bacteria,1U26T@1239|Firmicutes,24AQ8@186801|Clostridia,36GMQ@31979|Clostridiaceae	186801|Clostridia	G	Aldose 1-epimerase	lacX	-	-	-	-	-	-	-	-	-	-	-	Aldose_epim
k141_2757_107	1347392.CCEZ01000020_gene940	2.34e-41	137.0	COG0776@1|root,COG0776@2|Bacteria,1V9XQ@1239|Firmicutes,24MM0@186801|Clostridia,36KID@31979|Clostridiaceae	186801|Clostridia	L	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions	hup	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
k141_2757_108	293826.Amet_2653	4.48e-173	495.0	COG0436@1|root,COG0436@2|Bacteria,1TP0J@1239|Firmicutes,247NQ@186801|Clostridia,36DUZ@31979|Clostridiaceae	186801|Clostridia	E	Aminotransferase	aspC	-	2.6.1.1	ko:K00812,ko:K10907	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
k141_2757_109	1128398.Curi_c25510	9.52e-260	720.0	COG0161@1|root,COG0161@2|Bacteria,1TP9N@1239|Firmicutes,25E7B@186801|Clostridia,26AMQ@186813|unclassified Clostridiales	186801|Clostridia	H	Aminotransferase class-III	bioA	-	2.6.1.62	ko:K00833	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03231	RC00006,RC00887	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
k141_2757_110	1476973.JMMB01000007_gene482	7.4e-80	246.0	COG0132@1|root,COG0132@2|Bacteria,1UYA3@1239|Firmicutes,24F15@186801|Clostridia	186801|Clostridia	H	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring	bioD	-	6.3.3.3	ko:K01935	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03182	RC00868	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_26
k141_2757_111	469617.FUAG_00243	1.14e-45	153.0	COG1846@1|root,COG1846@2|Bacteria,37B0X@32066|Fusobacteria	32066|Fusobacteria	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR
k141_2757_112	1476973.JMMB01000007_gene1614	1.23e-134	394.0	COG2008@1|root,COG2008@2|Bacteria,1TPZI@1239|Firmicutes,248TR@186801|Clostridia,25QGA@186804|Peptostreptococcaceae	186801|Clostridia	E	Beta-eliminating lyase	ltaE	-	4.1.2.48	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	-	R00751,R06171	RC00312,RC00372	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
k141_2757_113	1121324.CLIT_10c01470	9.23e-72	222.0	COG2316@1|root,COG2316@2|Bacteria,1TSF7@1239|Firmicutes,24A1B@186801|Clostridia	186801|Clostridia	S	PFAM metal-dependent phosphohydrolase, HD sub domain	-	-	-	-	-	-	-	-	-	-	-	-	HD
k141_2757_114	573061.Clocel_4333	2.86e-88	275.0	COG1816@1|root,COG1816@2|Bacteria,1U44B@1239|Firmicutes,247KD@186801|Clostridia,36F6X@31979|Clostridiaceae	186801|Clostridia	F	adenosine deaminase	add	-	3.5.4.4	ko:K01488	ko00230,ko01100,ko05340,map00230,map01100,map05340	-	R01560,R02556	RC00477	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS13960	A_deaminase
k141_2757_115	1230342.CTM_14363	1.52e-166	512.0	COG0210@1|root,COG0210@2|Bacteria,1TRTJ@1239|Firmicutes,24BBH@186801|Clostridia,36EJQ@31979|Clostridiaceae	186801|Clostridia	L	DNA helicase	-	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RNase_T,UvrD-helicase,UvrD_C,UvrD_C_2
k141_4133_1	1304885.AUEY01000042_gene3596	1.76e-15	82.4	COG2199@1|root,COG3322@1|root,COG3322@2|Bacteria,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,42QMQ@68525|delta/epsilon subdivisions,2WN4S@28221|Deltaproteobacteria,2MJWK@213118|Desulfobacterales	28221|Deltaproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	DUF3365,GGDEF
k141_1084_1	870967.VIS19158_21406	3.45e-101	295.0	COG2801@1|root,COG2801@2|Bacteria,1PBHA@1224|Proteobacteria,1RQ7I@1236|Gammaproteobacteria,1XZJ7@135623|Vibrionales	135623|Vibrionales	L	PFAM Integrase, catalytic core	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_1084_2	1208321.D104_13695	8.29e-87	260.0	28I7P@1|root,2Z8AJ@2|Bacteria,1MY0A@1224|Proteobacteria,1RZAQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF3800)	rlfA	-	-	-	-	-	-	-	-	-	-	-	DUF3800
k141_1084_3	1219077.VAZ01S_058_00220	6.7e-245	693.0	COG0732@1|root,COG0732@2|Bacteria,1MXVH@1224|Proteobacteria,1RPS2@1236|Gammaproteobacteria,1XW85@135623|Vibrionales	135623|Vibrionales	V	restriction	-	-	3.1.21.3	ko:K01154	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	Methylase_S
k141_1084_4	1280001.BAOA01000047_gene1787	0.0	890.0	COG0286@1|root,COG0286@2|Bacteria,1MW3A@1224|Proteobacteria,1RRVF@1236|Gammaproteobacteria,1Y2E1@135623|Vibrionales	135623|Vibrionales	V	HsdM N-terminal domain	-	-	2.1.1.72	ko:K03427	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HsdM_N,N6_Mtase
k141_1084_5	223926.28805378	0.0	1393.0	COG4096@1|root,COG4096@2|Bacteria,1QTS7@1224|Proteobacteria,1RN63@1236|Gammaproteobacteria,1XUXP@135623|Vibrionales	135623|Vibrionales	L	COG4096 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases	-	-	3.1.21.3	ko:K01153	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	EcoEI_R_C,HSDR_N_2,Helicase_C,ResIII
k141_1084_6	316275.VSAL_I0961	5.37e-08	58.2	2DMZ2@1|root,32UH6@2|Bacteria,1N4V6@1224|Proteobacteria,1SBYX@1236|Gammaproteobacteria,1XY33@135623|Vibrionales	135623|Vibrionales	-	-	-	GO:0003674,GO:0003700,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141	-	-	-	-	-	-	-	-	-	-	-
k141_1084_7	1116375.VEJY3_22961	6.99e-52	165.0	COG1396@1|root,COG1396@2|Bacteria,1N8ZM@1224|Proteobacteria,1SD5C@1236|Gammaproteobacteria,1XYHC@135623|Vibrionales	135623|Vibrionales	K	Helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19,HTH_3
k141_1084_8	1188252.AJYK01000110_gene2439	4.67e-100	298.0	COG2842@1|root,COG2842@2|Bacteria,1R9BD@1224|Proteobacteria,1SCZF@1236|Gammaproteobacteria,1XX5T@135623|Vibrionales	135623|Vibrionales	S	Bacterial TniB protein	-	-	-	-	-	-	-	-	-	-	-	-	TniB
k141_1084_9	1517681.HW45_03125	3.82e-09	57.4	COG0610@1|root,COG0610@2|Bacteria,1MU96@1224|Proteobacteria,1RP2Q@1236|Gammaproteobacteria,1XTCP@135623|Vibrionales	135623|Vibrionales	L	Subunit R is required for both nuclease and ATPase activities, but not for modification	-	-	3.1.21.3	ko:K01153	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	DUF3387,HSDR_N,ResIII
k141_1084_11	1116375.VEJY3_11760	6.06e-97	295.0	2CQMA@1|root,32SMC@2|Bacteria,1N4QM@1224|Proteobacteria,1SC1G@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_4
k141_1084_14	869209.Tresu_0651	4.86e-16	77.0	28MA6@1|root,2ZANZ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_1084_15	1188252.AJYK01000110_gene2437	1.23e-28	109.0	2BVEU@1|root,32QUD@2|Bacteria,1RJ4J@1224|Proteobacteria,1S5X1@1236|Gammaproteobacteria,1XYDC@135623|Vibrionales	135623|Vibrionales	S	TnsA endonuclease N terminal	-	-	-	-	-	-	-	-	-	-	-	-	Tn7_Tnp_TnsA_N
k141_1084_17	316275.VSAL_I1967	4.18e-82	245.0	COG1522@1|root,COG1522@2|Bacteria,1RDB3@1224|Proteobacteria,1S2E1@1236|Gammaproteobacteria,1XWVX@135623|Vibrionales	135623|Vibrionales	K	Transcriptional regulator AsnC family	ybaO	-	-	ko:K05800	-	-	-	-	ko00000,ko03000	-	-	-	AsnC_trans_reg,HTH_24,HTH_AsnC-type
k141_2100_3	1286171.EAL2_c03620	1.8e-69	231.0	COG1538@1|root,COG1538@2|Bacteria,1TRDS@1239|Firmicutes,24H3M@186801|Clostridia	186801|Clostridia	MU	PFAM Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
k141_2100_4	350688.Clos_2601	1.84e-49	189.0	COG1404@1|root,COG1404@2|Bacteria,1UJN4@1239|Firmicutes,25F63@186801|Clostridia	186801|Clostridia	O	S-layer homology domain	-	-	-	-	-	-	-	-	-	-	-	-	SLH
k141_2100_5	1122143.AUEG01000012_gene1719	0.000194	47.0	COG0745@1|root,COG0745@2|Bacteria,1TPWS@1239|Firmicutes,4H9KP@91061|Bacilli,27FKB@186828|Carnobacteriaceae	91061|Bacilli	T	Transcriptional regulatory protein, C terminal	phoP	-	-	ko:K07658	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
k141_2100_6	1121324.CLIT_13c01150	4.17e-114	331.0	COG0176@1|root,COG0176@2|Bacteria,1TP4Q@1239|Firmicutes,248KZ@186801|Clostridia,25QSS@186804|Peptostreptococcaceae	186801|Clostridia	H	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	tal	-	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
k141_2100_7	1476973.JMMB01000007_gene3226	7.79e-156	446.0	COG1494@1|root,COG1494@2|Bacteria,1TP0D@1239|Firmicutes,249PW@186801|Clostridia,25QUF@186804|Peptostreptococcaceae	186801|Clostridia	G	Bacterial fructose-1,6-bisphosphatase, glpX-encoded	glpX	-	3.1.3.11	ko:K02446	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00165,M00167	R00762,R04780	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FBPase_glpX
k141_2100_8	1286171.EAL2_c03700	2.63e-210	596.0	COG1158@1|root,COG1158@2|Bacteria,1TPHZ@1239|Firmicutes,247YK@186801|Clostridia,25V0W@186806|Eubacteriaceae	186801|Clostridia	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
k141_2100_9	997346.HMPREF9374_2413	5.51e-28	102.0	COG0254@1|root,COG0254@2|Bacteria,1VEGU@1239|Firmicutes,4HNQF@91061|Bacilli,27C9Y@186824|Thermoactinomycetaceae	91061|Bacilli	J	Ribosomal protein L31	rpmE	-	-	ko:K02909	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31
k141_2100_10	1540257.JQMW01000013_gene916	5.81e-95	281.0	COG1435@1|root,COG1435@2|Bacteria,1TRVM@1239|Firmicutes,24CVH@186801|Clostridia,36DU8@31979|Clostridiaceae	186801|Clostridia	F	thymidine kinase	tdk	-	2.7.1.21	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01567,R02099,R08233	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	TK
k141_2100_11	1121324.CLIT_13c01210	5.05e-129	377.0	COG3872@1|root,COG3872@2|Bacteria,1TPBU@1239|Firmicutes,25C8E@186801|Clostridia,25R91@186804|Peptostreptococcaceae	186801|Clostridia	S	Protein of unknown function (DUF1385)	prmC	-	-	-	-	-	-	-	-	-	-	-	DUF1385,MTS
k141_2100_12	596329.HMPREF0631_1196	2.3e-64	211.0	COG2890@1|root,COG2890@2|Bacteria,1TSMA@1239|Firmicutes,24838@186801|Clostridia,25TC8@186804|Peptostreptococcaceae	186801|Clostridia	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif	prmC	-	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS,Methyltransf_31
k141_2100_13	1121324.CLIT_13c01230	1.69e-178	506.0	COG0216@1|root,COG0216@2|Bacteria,1TQ7V@1239|Firmicutes,248CN@186801|Clostridia,25QD5@186804|Peptostreptococcaceae	186801|Clostridia	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
k141_3561_1	113395.AXAI01000010_gene2184	5.34e-11	63.5	COG4239@1|root,COG4239@2|Bacteria,1MUM5@1224|Proteobacteria,2TR1Y@28211|Alphaproteobacteria,3JSKV@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	P	N-terminal TM domain of oligopeptide transport permease C	yejE	GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006857,GO:0008150,GO:0015833,GO:0015893,GO:0016020,GO:0035672,GO:0042221,GO:0042493,GO:0042884,GO:0042886,GO:0042891,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944	-	ko:K13895	ko02010,map02010	M00349	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.21,3.A.1.5.24	-	-	BPD_transp_1,OppC_N
k141_3561_2	525897.Dbac_1349	4.02e-48	164.0	COG4174@1|root,COG4174@2|Bacteria,1MVKE@1224|Proteobacteria,43BKS@68525|delta/epsilon subdivisions,2X6YW@28221|Deltaproteobacteria,2M9NN@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K13894	ko02010,map02010	M00349	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.21,3.A.1.5.24	-	-	BPD_transp_1
k141_1244_1	745411.B3C1_10782	5.24e-71	243.0	COG2373@1|root,COG2373@2|Bacteria,1MV7J@1224|Proteobacteria,1RNRY@1236|Gammaproteobacteria,1J8TQ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Alpha-2-Macroglobulin	-	-	-	ko:K06894	-	-	-	-	ko00000	-	-	-	A2M,A2M_N,A2M_N_2,MG1,Thiol-ester_cl
k141_1244_2	1219076.N646_3715	1.5e-11	64.3	COG0459@1|root,COG0459@2|Bacteria,1MURR@1224|Proteobacteria,1RMTB@1236|Gammaproteobacteria,1XVGV@135623|Vibrionales	135623|Vibrionales	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL2	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
k141_1244_3	1517681.HW45_16475	0.0	931.0	COG3345@1|root,COG3345@2|Bacteria,1MWTQ@1224|Proteobacteria,1RQ4M@1236|Gammaproteobacteria,1XUYH@135623|Vibrionales	135623|Vibrionales	G	COG3345 Alpha-galactosidase	-	-	3.2.1.22	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	-	R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091	RC00049,RC00059,RC00451	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_36C,Glyco_hydro_36N,Melibiase
k141_1244_4	345073.VC395_2453	5.48e-101	325.0	COG3250@1|root,COG3250@2|Bacteria,1MVBN@1224|Proteobacteria,1RMER@1236|Gammaproteobacteria,1XUKN@135623|Vibrionales	135623|Vibrionales	G	COG3250 Beta-galactosidase beta-glucuronidase	lacZ	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	Bgal_small_N,DUF4981,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
k141_4613_1	545693.BMQ_0220	8.98e-53	186.0	COG0770@1|root,COG0770@2|Bacteria,1VT78@1239|Firmicutes,4HACR@91061|Bacilli,1ZCC3@1386|Bacillus	91061|Bacilli	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
k141_4613_2	1121405.dsmv_3411	3.02e-108	337.0	COG0769@1|root,COG0769@2|Bacteria,1MU6P@1224|Proteobacteria,42NKY@68525|delta/epsilon subdivisions,2WJJG@28221|Deltaproteobacteria,2MHKD@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008765,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
k141_2485_1	177439.DP2257	4.36e-209	588.0	COG2206@1|root,COG2206@2|Bacteria,1R53C@1224|Proteobacteria,42R7P@68525|delta/epsilon subdivisions,2WMSW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	metal-dependent phosphohydrolase HD region	-	-	-	-	-	-	-	-	-	-	-	-	HD
k141_2485_2	1415780.JPOG01000001_gene1950	7.23e-19	84.0	2DPMS@1|root,332PR@2|Bacteria,1N9MC@1224|Proteobacteria,1SEWG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF2628)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2628
k141_2485_4	1238450.VIBNISOn1_790069	7.72e-195	546.0	COG1135@1|root,COG1135@2|Bacteria,1QTTK@1224|Proteobacteria,1RMQD@1236|Gammaproteobacteria,1XT41@135623|Vibrionales	135623|Vibrionales	P	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system	metN	GO:0003674,GO:0003824,GO:0005215,GO:0006810,GO:0008150,GO:0015399,GO:0015405,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0042623,GO:0042626,GO:0043492,GO:0051179,GO:0051234,GO:0055085	-	ko:K02071	ko02010,map02010	M00238	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.24	-	-	ABC_tran,NIL
k141_2485_5	312309.VF_0685	1.65e-116	338.0	COG2011@1|root,COG2011@2|Bacteria,1MW8E@1224|Proteobacteria,1RQ6I@1236|Gammaproteobacteria,1XTTW@135623|Vibrionales	135623|Vibrionales	P	COG2011 ABC-type metal ion transport system, permease component	metI	GO:0000101,GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006865,GO:0008150,GO:0015399,GO:0015405,GO:0015711,GO:0015821,GO:0015849,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0042623,GO:0042626,GO:0042940,GO:0043492,GO:0044464,GO:0046942,GO:0048473,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0072348	-	ko:K02072	ko02010,map02010	M00238	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.24	-	-	BPD_transp_1
k141_2485_6	870967.VIS19158_17311	3.27e-154	437.0	COG1464@1|root,COG1464@2|Bacteria,1MUVY@1224|Proteobacteria,1RS3R@1236|Gammaproteobacteria,1XU8C@135623|Vibrionales	135623|Vibrionales	M	Belongs to the nlpA lipoprotein family	metQ	-	-	ko:K02073	ko02010,map02010	M00238	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.24	-	-	Lipoprotein_9
k141_2485_7	945543.VIBR0546_18687	8.75e-163	458.0	COG5595@1|root,COG5595@2|Bacteria,1NDR3@1224|Proteobacteria,1RRXG@1236|Gammaproteobacteria,1XTPF@135623|Vibrionales	135623|Vibrionales	S	COG5595 Zn-ribbon-containing, possibly nucleic-acid-binding protein	HD1486	-	-	-	-	-	-	-	-	-	-	-	DUF2310
k141_2485_8	945550.VISI1226_02912	2.19e-67	210.0	28Q4G@1|root,2ZCMR@2|Bacteria,1RAB3@1224|Proteobacteria,1S2N3@1236|Gammaproteobacteria,1XVSC@135623|Vibrionales	135623|Vibrionales	S	Interacts with the SecY protein in vivo. May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function	syd	-	-	ko:K15723	-	-	-	-	ko00000	-	-	-	Syd
k141_2485_9	345073.VC395_0918	2.25e-143	411.0	COG0780@1|root,COG2904@1|root,COG0780@2|Bacteria,COG2904@2|Bacteria,1MW0M@1224|Proteobacteria,1RNXM@1236|Gammaproteobacteria,1XSYX@135623|Vibrionales	135623|Vibrionales	S	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)	queF	-	1.7.1.13	ko:K06879	ko00790,ko01100,map00790,map01100	-	R07605	RC01875	ko00000,ko00001,ko01000,ko03016	-	-	-	QueF,QueF_N
k141_2485_10	55601.VANGNB10_cI0777c	2.91e-271	773.0	COG0457@1|root,COG0457@2|Bacteria,1RDRI@1224|Proteobacteria,1S3PB@1236|Gammaproteobacteria,1XTIH@135623|Vibrionales	135623|Vibrionales	S	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_12
k141_2485_12	223926.28805683	6.04e-136	390.0	COG0258@1|root,COG0258@2|Bacteria,1MX9Y@1224|Proteobacteria,1RQZE@1236|Gammaproteobacteria,1XTDZ@135623|Vibrionales	135623|Vibrionales	L	Has flap endonuclease activity. During DNA replication, flap endonucleases cleave the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment	xni	GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0006139,GO:0006259,GO:0006281,GO:0006308,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016787,GO:0016788,GO:0019439,GO:0033554,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:1901360,GO:1901361,GO:1901575	-	ko:K01146	-	-	-	-	ko00000	-	-	-	5_3_exonuc,5_3_exonuc_N
k141_2485_14	1219077.VAZ01S_025_00210	1.33e-40	139.0	COG2363@1|root,COG2363@2|Bacteria,1MZX3@1224|Proteobacteria,1SCNB@1236|Gammaproteobacteria,1XXBJ@135623|Vibrionales	135623|Vibrionales	S	small membrane protein	ygdD	-	-	-	-	-	-	-	-	-	-	-	DUF423
k141_2485_15	870967.VIS19158_21276	3.35e-85	258.0	COG3571@1|root,COG3571@2|Bacteria,1RD20@1224|Proteobacteria,1S3Y4@1236|Gammaproteobacteria,1XU58@135623|Vibrionales	135623|Vibrionales	S	hydrolase of the alpha beta-hydrolase fold	-	-	-	ko:K07020	-	-	-	-	ko00000	-	-	-	Abhydrolase_1,Abhydrolase_6,DLH
k141_2485_16	1348635.BBJY01000020_gene2722	4.22e-179	503.0	COG0583@1|root,COG0583@2|Bacteria,1MWY0@1224|Proteobacteria,1RP7Q@1236|Gammaproteobacteria,1XUQR@135623|Vibrionales	135623|Vibrionales	K	Transcriptional regulator	gcvA	-	-	ko:K03566	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_1,LysR_substrate
k141_2485_17	55601.VANGNB10_cI0770	2.85e-285	786.0	COG0301@1|root,COG0607@1|root,COG0301@2|Bacteria,COG0607@2|Bacteria,1MWD3@1224|Proteobacteria,1RNZT@1236|Gammaproteobacteria,1XT1D@135623|Vibrionales	135623|Vibrionales	H	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS	thiI	GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.8.1.4	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07461	-	ko00000,ko00001,ko01000,ko03016	-	-	-	THUMP,ThiI
k141_2485_18	345073.VC395_0909	6.3e-164	466.0	COG1360@1|root,COG1360@2|Bacteria,1QUFR@1224|Proteobacteria,1T1XE@1236|Gammaproteobacteria,1XSEG@135623|Vibrionales	135623|Vibrionales	N	Flagellar motor protein	motB	-	-	ko:K02557	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	MotB_plug,OmpA
k141_2485_19	796620.VIBC2010_13021	8.23e-152	430.0	COG1291@1|root,COG1291@2|Bacteria,1MXK3@1224|Proteobacteria,1RNRP@1236|Gammaproteobacteria,1XSQE@135623|Vibrionales	135623|Vibrionales	N	COG1291 Flagellar motor component	pomA	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0009288,GO:0009425,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0042995,GO:0043226,GO:0043228,GO:0044422,GO:0044425,GO:0044459,GO:0044461,GO:0044463,GO:0044464,GO:0071944,GO:0120100,GO:0120101	-	ko:K02556	ko02020,ko02030,ko02040,map02020,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	MotA_ExbB
k141_2485_20	55601.VANGNB10_cI0767c	1.68e-32	114.0	COG1722@1|root,COG1722@2|Bacteria,1N72V@1224|Proteobacteria,1SC7N@1236|Gammaproteobacteria,1XYBF@135623|Vibrionales	135623|Vibrionales	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseB	GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008855,GO:0009056,GO:0009057,GO:0009318,GO:0009987,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0019439,GO:0032991,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575,GO:1902494	3.1.11.6	ko:K03602	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_S
k141_2485_21	1348635.BBJY01000020_gene2728	1.06e-160	456.0	COG0142@1|root,COG0142@2|Bacteria,1MWNG@1224|Proteobacteria,1RMKY@1236|Gammaproteobacteria,1XTUM@135623|Vibrionales	135623|Vibrionales	H	Belongs to the FPP GGPP synthase family	ispA	-	2.5.1.1,2.5.1.10	ko:K00795	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364	R01658,R02003	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
k141_2485_22	243277.VC_0889	0.0	1056.0	COG1154@1|root,COG1154@2|Bacteria,1MUSJ@1224|Proteobacteria,1RNQD@1236|Gammaproteobacteria,1XSY2@135623|Vibrionales	135623|Vibrionales	H	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)	dxs	GO:0003674,GO:0003824,GO:0006629,GO:0006720,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008614,GO:0008615,GO:0008661,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016744,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0042816,GO:0042819,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	-	DXP_synthase_N,Transket_pyr,Transketolase_C
k141_2485_23	272558.10173676	2.19e-266	755.0	COG3661@1|root,COG3661@2|Bacteria,1UKA3@1239|Firmicutes,4HDZV@91061|Bacilli,1ZCXN@1386|Bacillus	91061|Bacilli	G	Belongs to the glycosyl hydrolase 67 family	aguA	-	3.2.1.139	ko:K01235	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_hydro_67C,Glyco_hydro_67M,Glyco_hydro_67N
k141_2485_24	1114922.CIFAM_10_00260	2.85e-120	370.0	COG2211@1|root,COG2211@2|Bacteria,1QXCB@1224|Proteobacteria,1RYE7@1236|Gammaproteobacteria,3WXXA@544|Citrobacter	1236|Gammaproteobacteria	G	MFS/sugar transport protein	-	-	-	ko:K16210	-	-	-	-	ko00000,ko02000	2.A.2.5	-	-	MFS_2
k141_2485_25	55601.VANGNB10_cI0764	2.67e-141	402.0	COG0564@1|root,COG0564@2|Bacteria,1N8GW@1224|Proteobacteria,1RMZ7@1236|Gammaproteobacteria,1XSJX@135623|Vibrionales	135623|Vibrionales	J	COG0564 Pseudouridylate synthases, 23S RNA-specific	truC	GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360	5.4.99.26	ko:K06175	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_2
k141_2485_26	55601.VANGNB10_cI0763	3.25e-24	95.5	COG3098@1|root,COG3098@2|Bacteria,1N7AG@1224|Proteobacteria,1SCXJ@1236|Gammaproteobacteria,1XYYN@135623|Vibrionales	135623|Vibrionales	S	protein conserved in bacteria	VV2562	-	-	-	-	-	-	-	-	-	-	-	DUF446
k141_2485_27	223926.28807322	1.27e-159	457.0	28K8N@1|root,2Z9WC@2|Bacteria,1R5V8@1224|Proteobacteria,1S3I5@1236|Gammaproteobacteria,1XUIP@135623|Vibrionales	135623|Vibrionales	S	Protein of unknown function (DUF3549)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3549
k141_2485_29	345073.VC395_0900	1.19e-50	168.0	COG1670@1|root,COG1670@2|Bacteria,1RK72@1224|Proteobacteria,1S6IJ@1236|Gammaproteobacteria,1XX66@135623|Vibrionales	135623|Vibrionales	J	COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
k141_2485_30	672.VV93_v1c22850	4.1e-21	87.0	2CEIZ@1|root,33JKV@2|Bacteria,1NMVX@1224|Proteobacteria,1SHB5@1236|Gammaproteobacteria,1XYIQ@135623|Vibrionales	135623|Vibrionales	-	-	SO1611	-	-	-	-	-	-	-	-	-	-	-	-
k141_2485_31	243277.VC_0881	7.39e-79	237.0	COG1671@1|root,COG1671@2|Bacteria,1RCZA@1224|Proteobacteria,1S3QM@1236|Gammaproteobacteria,1XWZB@135623|Vibrionales	135623|Vibrionales	S	Belongs to the UPF0178 family	yaiI	-	-	ko:K09768	-	-	-	-	ko00000	-	-	-	DUF188
k141_2485_32	1280001.BAOA01000081_gene2966	4.03e-120	348.0	COG1720@1|root,COG1720@2|Bacteria,1MUF0@1224|Proteobacteria,1RPCX@1236|Gammaproteobacteria,1XU35@135623|Vibrionales	135623|Vibrionales	S	Uncharacterised protein family UPF0066	yaeB	-	-	-	-	-	-	-	-	-	-	-	UPF0066
k141_2485_33	1348635.BBJY01000020_gene2738	0.0	1025.0	COG0442@1|root,COG0442@2|Bacteria,1MU7E@1224|Proteobacteria,1RN5R@1236|Gammaproteobacteria,1XTZ6@135623|Vibrionales	135623|Vibrionales	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS	proS	GO:0003674,GO:0003824,GO:0004812,GO:0004827,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006433,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_edit
k141_549_29	1517681.HW45_23865	3.58e-106	310.0	COG0632@1|root,COG0632@2|Bacteria,1MWJR@1224|Proteobacteria,1RMET@1236|Gammaproteobacteria,1XSGY@135623|Vibrionales	135623|Vibrionales	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB	ruvA	GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0006139,GO:0006259,GO:0006310,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009378,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0032392,GO:0032508,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_C,RuvA_N
k141_549_30	1205908.AKXW01000004_gene3115	1.15e-202	565.0	COG2255@1|root,COG2255@2|Bacteria,1MU38@1224|Proteobacteria,1RNWY@1236|Gammaproteobacteria,1XV8V@135623|Vibrionales	135623|Vibrionales	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0006139,GO:0006259,GO:0006310,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009378,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0032392,GO:0032508,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
k141_549_32	243277.VC_1844	1.38e-314	865.0	COG1271@1|root,COG1271@2|Bacteria,1MV60@1224|Proteobacteria,1RN2U@1236|Gammaproteobacteria,1XT5F@135623|Vibrionales	135623|Vibrionales	C	COG1271 Cytochrome bd-type quinol oxidase, subunit 1	cydA	-	1.10.3.14	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	Cyt_bd_oxida_I
k141_549_33	55601.VANGNB10_cI1671c	8.63e-209	584.0	COG1294@1|root,COG1294@2|Bacteria,1MURP@1224|Proteobacteria,1RP7F@1236|Gammaproteobacteria,1XVFM@135623|Vibrionales	135623|Vibrionales	C	COG1294 Cytochrome bd-type quinol oxidase, subunit 2	cydB	-	1.10.3.14	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	Cyt_bd_oxida_II
k141_549_36	945550.VISI1226_13291	8.62e-54	172.0	COG0824@1|root,COG0824@2|Bacteria,1MZH6@1224|Proteobacteria,1S93F@1236|Gammaproteobacteria,1XXKJ@135623|Vibrionales	135623|Vibrionales	S	Thioesterase-like superfamily	ybgC	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT
k141_549_37	870967.VIS19158_14642	1.06e-114	334.0	COG0811@1|root,COG0811@2|Bacteria,1NCWW@1224|Proteobacteria,1RMD4@1236|Gammaproteobacteria,1XUNH@135623|Vibrionales	135623|Vibrionales	U	COG0811 Biopolymer transport proteins	tolQ	-	-	ko:K03562	ko01120,map01120	-	-	-	ko00000,ko02000	1.A.30.2.2	-	-	MotA_ExbB
k141_549_38	945550.VISI1226_13301	5.59e-73	222.0	COG0848@1|root,COG0848@2|Bacteria,1MZ6M@1224|Proteobacteria,1S8RS@1236|Gammaproteobacteria,1XWZR@135623|Vibrionales	135623|Vibrionales	U	TolR membrane protein	tolR	-	-	ko:K03560	-	-	-	-	ko00000,ko02000	1.A.30.2.2	-	-	ExbD
k141_549_39	675814.VIC_004558	2.56e-42	157.0	COG3064@1|root,COG3064@2|Bacteria,1MVQS@1224|Proteobacteria,1RP2V@1236|Gammaproteobacteria,1XSTI@135623|Vibrionales	135623|Vibrionales	M	COG3064 Membrane protein involved in colicin uptake	tolA	-	-	ko:K03646	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	TolA
k141_549_40	1348635.BBJY01000013_gene970	4.28e-179	515.0	COG0823@1|root,COG0823@2|Bacteria,1MV09@1224|Proteobacteria,1RMCY@1236|Gammaproteobacteria,1XSZN@135623|Vibrionales	135623|Vibrionales	U	Involved in the TonB-independent uptake of proteins	tolB	GO:0003674,GO:0005215	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40,TolB_N
k141_549_41	55601.VANGNB10_cI1663c	9e-72	221.0	COG2885@1|root,COG2885@2|Bacteria,1MZTV@1224|Proteobacteria,1S8RG@1236|Gammaproteobacteria,1XV6J@135623|Vibrionales	135623|Vibrionales	M	Belongs to the ompA family	pal	-	-	ko:K03640	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	OmpA
k141_549_42	672.VV93_v1c19830	8.99e-91	275.0	COG1729@1|root,COG1729@2|Bacteria,1MUSV@1224|Proteobacteria,1RQWA@1236|Gammaproteobacteria,1XSAP@135623|Vibrionales	135623|Vibrionales	D	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division	cpoB	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6,TPR_8,TolA_bind_tri
k141_549_44	1348635.BBJY01000013_gene966	1.13e-74	229.0	COG3318@1|root,COG3318@2|Bacteria,1N0JQ@1224|Proteobacteria,1SUIC@1236|Gammaproteobacteria,1XTR3@135623|Vibrionales	135623|Vibrionales	S	Belongs to the UPF0149 family	-	-	-	ko:K07039	-	-	-	-	ko00000	-	-	-	UPF0149
k141_549_45	1348635.BBJY01000013_gene965	9.65e-276	788.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,1SKKJ@1236|Gammaproteobacteria,1XT1G@135623|Vibrionales	135623|Vibrionales	T	COG0642 Signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,Response_reg,dCache_1
k141_549_46	1348635.BBJY01000013_gene964	1.06e-82	246.0	2940Y@1|root,2ZRFS@2|Bacteria,1RF8A@1224|Proteobacteria,1RZCB@1236|Gammaproteobacteria,1XX6B@135623|Vibrionales	135623|Vibrionales	U	L-alanine exporter AlaE	alaE	-	-	-	-	-	-	-	-	-	-	-	AlaE
k141_549_47	706587.Desti_4370	2.34e-10	67.0	COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,42MK4@68525|delta/epsilon subdivisions,2WJJ8@28221|Deltaproteobacteria,2MR9B@213462|Syntrophobacterales	28221|Deltaproteobacteria	G	transporter, DctM subunit	-	-	-	ko:K11690	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.56.1	-	-	DctM
k141_549_48	1117315.AHCA01000031_gene1544	9.49e-103	318.0	COG4694@1|root,COG4694@2|Bacteria,1PRHR@1224|Proteobacteria,1RP2B@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	AAA_13
k141_3581_1	411902.CLOBOL_02277	1.39e-57	185.0	COG3090@1|root,COG3090@2|Bacteria,1V3PZ@1239|Firmicutes,24HA7@186801|Clostridia,2213T@1506553|Lachnoclostridium	186801|Clostridia	G	COG COG3090 TRAP-type C4-dicarboxylate transport system, small permease component	-	-	-	-	-	-	-	-	-	-	-	-	DctQ
k141_265_1	574087.Acear_1191	5.53e-41	144.0	arCOG09719@1|root,2Z7NA@2|Bacteria,1TSE4@1239|Firmicutes,24FF3@186801|Clostridia,3WB05@53433|Halanaerobiales	186801|Clostridia	S	Protein of unknown function (DUF3100)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3100
k141_4628_1	1123274.KB899416_gene2629	1.17e-241	677.0	COG0714@1|root,COG0714@2|Bacteria	2|Bacteria	KLT	Associated with various cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	AAA_11,AAA_12,AAA_3,AAA_5,DUF3320,DUF4011
k141_2212_2	1125863.JAFN01000001_gene3112	3.37e-84	265.0	28QK0@1|root,2ZD1U@2|Bacteria,1NFK4@1224|Proteobacteria,42VSJ@68525|delta/epsilon subdivisions,2WRIZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_2212_4	1437882.AZRU01000009_gene902	1.09e-135	416.0	COG1123@1|root,COG4239@1|root,COG4172@2|Bacteria,COG4239@2|Bacteria,1MU09@1224|Proteobacteria,1RMEI@1236|Gammaproteobacteria,1YFBM@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	P	Belongs to the ABC transporter superfamily	yejF	GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006857,GO:0008144,GO:0008150,GO:0015399,GO:0015405,GO:0015833,GO:0015893,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0035672,GO:0036094,GO:0042221,GO:0042493,GO:0042623,GO:0042626,GO:0042884,GO:0042886,GO:0042891,GO:0043167,GO:0043168,GO:0043492,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	ko:K13896	ko02010,map02010	M00349	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.21,3.A.1.5.24	-	-	ABC_tran,oligo_HPY
k141_1516_1	485915.Dret_1961	2.28e-263	731.0	COG0591@1|root,COG0591@2|Bacteria,1QZ58@1224|Proteobacteria,43CY5@68525|delta/epsilon subdivisions,2X869@28221|Deltaproteobacteria,2MHC8@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K11928	-	-	-	-	ko00000,ko02000	2.A.21.2	-	-	SSF
k141_1516_3	1123371.ATXH01000016_gene1825	1.66e-116	342.0	COG2998@1|root,COG2998@2|Bacteria,2GHF5@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	H	Bacterial extracellular solute-binding protein	-	-	-	ko:K05772	ko02010,map02010	M00186	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.2,3.A.1.6.4	-	-	PBP_like_2
k141_551_1	743722.Sph21_2251	1.92e-18	84.7	COG1960@1|root,COG1960@2|Bacteria,4NEHA@976|Bacteroidetes,1IP19@117747|Sphingobacteriia	976|Bacteroidetes	I	acyl-CoA dehydrogenase	acdA	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
k141_551_2	421072.IO89_05790	1.47e-36	135.0	COG1960@1|root,COG1960@2|Bacteria,4NEHA@976|Bacteroidetes,1HWV4@117743|Flavobacteriia,3HH2I@358033|Chryseobacterium	976|Bacteroidetes	I	Acyl-CoA dehydrogenase, C-terminal domain	acdA	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
k141_2213_1	307480.IW16_10385	6.11e-07	58.2	COG0666@1|root,COG3779@1|root,COG0666@2|Bacteria,COG3779@2|Bacteria,4NFKS@976|Bacteroidetes,1HYN8@117743|Flavobacteriia,3ZNVN@59732|Chryseobacterium	976|Bacteroidetes	S	Uncharacterized protein conserved in bacteria (DUF2314)	-	-	-	-	-	-	-	-	-	-	-	-	Ank_5,DUF2314
k141_552_1	177437.HRM2_39350	9.03e-41	136.0	2EDCF@1|root,3378R@2|Bacteria,1NDPM@1224|Proteobacteria,42WBA@68525|delta/epsilon subdivisions,2WSE2@28221|Deltaproteobacteria,2MM1G@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_552_2	929704.Myrod_0849	4.08e-87	264.0	COG3878@1|root,COG3878@2|Bacteria,4NNDU@976|Bacteroidetes,1I1VJ@117743|Flavobacteriia,47I4Q@76831|Myroides	976|Bacteroidetes	S	Domain of unknown function (DUF1963)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1963
k141_267_3	1515746.HR45_19160	4.3e-25	96.7	COG4453@1|root,COG4453@2|Bacteria,1N0BK@1224|Proteobacteria,1S8UN@1236|Gammaproteobacteria,2QD1W@267890|Shewanellaceae	1236|Gammaproteobacteria	S	Protein of unknown function (DUF1778)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1778
k141_267_4	202955.BBND01000002_gene539	1.88e-19	87.8	COG0454@1|root,COG0454@2|Bacteria,1QUS5@1224|Proteobacteria,1T300@1236|Gammaproteobacteria,3NTP6@468|Moraxellaceae	1236|Gammaproteobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_10
k141_3917_3	1278307.KB906980_gene4142	0.0	1025.0	COG0025@1|root,COG0025@2|Bacteria,1MW5T@1224|Proteobacteria,1RPH6@1236|Gammaproteobacteria,2QIQN@267894|Psychromonadaceae	1236|Gammaproteobacteria	P	Cyclic nucleotide-monophosphate binding domain	-	-	-	ko:K03316	-	-	-	-	ko00000	2.A.36	-	-	Na_H_Exchanger,cNMP_binding
k141_3225_2	700598.Niako_0073	8.19e-142	423.0	COG3401@1|root,COG3401@2|Bacteria,4NIS0@976|Bacteroidetes,1IV2B@117747|Sphingobacteriia	976|Bacteroidetes	M	Domain of unknown function	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,DUF1565,DUF4990
k141_3225_3	1348635.BBJY01000006_gene493	1.19e-273	754.0	COG2115@1|root,COG2115@2|Bacteria,1MXS2@1224|Proteobacteria,1RN5Y@1236|Gammaproteobacteria,1XVAY@135623|Vibrionales	135623|Vibrionales	G	Belongs to the xylose isomerase family	xylA	-	5.3.1.5	ko:K01805	ko00040,ko00051,ko01100,map00040,map00051,map01100	-	R00878,R01432	RC00376,RC00516	ko00000,ko00001,ko01000	-	-	-	-
k141_3225_5	1278307.KB906982_gene4004	2.74e-195	551.0	COG1609@1|root,COG2207@1|root,COG1609@2|Bacteria,COG2207@2|Bacteria,1NYTD@1224|Proteobacteria,1RNGZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	transcriptional regulator	xylR	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	HTH_18,HTH_AraC,Peripla_BP_3
k141_3225_6	357804.Ping_0224	4.58e-238	667.0	COG1070@1|root,COG1070@2|Bacteria,1MW4A@1224|Proteobacteria,1RR7X@1236|Gammaproteobacteria,2QIJC@267894|Psychromonadaceae	1236|Gammaproteobacteria	G	FGGY family of carbohydrate kinases, N-terminal domain	xylB	GO:0003674,GO:0003824,GO:0004856,GO:0005975,GO:0005996,GO:0005997,GO:0005998,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016052,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019200,GO:0019321,GO:0019323,GO:0042732,GO:0042843,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0046365,GO:0046835,GO:0071704,GO:1901575	2.7.1.17	ko:K00854	ko00040,ko01100,map00040,map01100	M00014	R01639	RC00002,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	iAPECO1_1312.APECO1_2885,iEC55989_1330.EC55989_4019,iECIAI1_1343.ECIAI1_3729,iECO103_1326.ECO103_4670,iECO111_1330.ECO111_4384,iECO26_1355.ECO26_5037,iECOK1_1307.ECOK1_4011,iECP_1309.ECP_3667,iECS88_1305.ECS88_3982,iECSE_1348.ECSE_3838,iECW_1372.ECW_m3838,iEKO11_1354.EKO11_0162,iUMN146_1321.UM146_17990,iUTI89_1310.UTI89_C4105,iWFL_1372.ECW_m3838	FGGY_C,FGGY_N
k141_3225_7	595494.Tola_3107	5.87e-221	627.0	COG2272@1|root,COG2272@2|Bacteria,1MVQZ@1224|Proteobacteria,1RPFW@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	Belongs to the type-B carboxylesterase lipase family	pnbA	-	-	ko:K03929	-	-	-	-	ko00000,ko01000	-	CE10	-	COesterase
k141_3225_8	1116375.VEJY3_16641	2.4e-141	449.0	COG5373@1|root,COG5373@2|Bacteria,1N08V@1224|Proteobacteria,1THF8@1236|Gammaproteobacteria,1XVAB@135623|Vibrionales	135623|Vibrionales	S	Predicted membrane protein (DUF2339)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2339
k141_3225_10	400668.Mmwyl1_3841	5.63e-107	327.0	COG0477@1|root,COG2814@2|Bacteria,1MU9G@1224|Proteobacteria,1RPHV@1236|Gammaproteobacteria,1XPQ0@135619|Oceanospirillales	135619|Oceanospirillales	EGP	Major Facilitator Superfamily	-	-	-	ko:K08159	-	-	-	-	ko00000,ko02000	2.A.1.2.15,2.A.1.2.18	-	-	MFS_1
k141_3225_11	675814.VIC_002519	1.14e-69	215.0	COG1057@1|root,COG1057@2|Bacteria,1N1IS@1224|Proteobacteria,1SA2H@1236|Gammaproteobacteria,1XWZ4@135623|Vibrionales	135623|Vibrionales	H	adenylyltransferase	nadD	-	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
k141_3225_12	1348635.BBJY01000001_gene2684	5.45e-247	692.0	COG0784@1|root,COG3437@1|root,COG0784@2|Bacteria,COG3437@2|Bacteria,1NC9X@1224|Proteobacteria,1T1YW@1236|Gammaproteobacteria,1Y337@135623|Vibrionales	135623|Vibrionales	T	COG3437 Response regulator containing a CheY-like receiver domain and an HD-GYP domain	-	GO:0000156,GO:0000160,GO:0003674,GO:0003824,GO:0004112,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008081,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009187,GO:0009214,GO:0009987,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0023052,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035556,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055086,GO:0060089,GO:0065007,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576	-	-	-	-	-	-	-	-	-	-	DUF3369,HD,HD_5,Response_reg
k141_3225_13	55601.VANGNB10_cII0209c	1.95e-240	686.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,1RN52@1236|Gammaproteobacteria,1XTD4@135623|Vibrionales	135623|Vibrionales	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE5,HATPase_c
k141_3225_14	1348635.BBJY01000001_gene2686	3.81e-86	269.0	COG2984@1|root,COG2984@2|Bacteria,1RA9N@1224|Proteobacteria,1S2YI@1236|Gammaproteobacteria,1XTSK@135623|Vibrionales	135623|Vibrionales	S	ABC transporter substrate binding protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC_sub_bind
k141_3225_15	400668.Mmwyl1_4064	6.08e-120	355.0	COG0697@1|root,COG0697@2|Bacteria,1PGSE@1224|Proteobacteria,1RMZY@1236|Gammaproteobacteria,1XPQY@135619|Oceanospirillales	135619|Oceanospirillales	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
k141_3225_16	1232666.JANE01000082_gene523	1.45e-08	55.1	COG1359@1|root,COG1359@2|Bacteria,1VG4T@1239|Firmicutes,4HPNQ@91061|Bacilli,4H1KA@90964|Staphylococcaceae	91061|Bacilli	S	Antibiotic biosynthesis monooxygenase	ycnE	GO:0003674,GO:0003824	-	-	-	-	-	-	-	-	-	-	ABM
k141_3225_17	570268.ANBB01000049_gene3572	1.28e-167	514.0	COG1472@1|root,COG1472@2|Bacteria,2GJ5H@201174|Actinobacteria,4EI5W@85012|Streptosporangiales	201174|Actinobacteria	G	Fibronectin type III-like domain	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C,Ricin_B_lectin
k141_3225_18	1348635.BBJY01000001_gene2340	6.15e-211	595.0	COG1488@1|root,COG1488@2|Bacteria,1MV8U@1224|Proteobacteria,1RQWS@1236|Gammaproteobacteria,1XSPB@135623|Vibrionales	135623|Vibrionales	F	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP	pncB	GO:0003674,GO:0003824,GO:0004516,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009987,GO:0016874,GO:0016879,GO:0019362,GO:0019637,GO:0019674,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901360,GO:1901564	6.3.4.21	ko:K00763	ko00760,ko01100,map00760,map01100	-	R01724	RC00033	ko00000,ko00001,ko01000	-	-	-	NAPRTase
k141_3225_19	1348635.BBJY01000001_gene2341	4.9e-136	389.0	COG1051@1|root,COG1051@2|Bacteria,1QTT4@1224|Proteobacteria,1RQ35@1236|Gammaproteobacteria,1XUIX@135623|Vibrionales	135623|Vibrionales	F	COG1051 ADP-ribose pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
k141_3225_21	223926.28808849	1.96e-55	180.0	COG5413@1|root,COG5413@2|Bacteria,1NA15@1224|Proteobacteria,1SCSY@1236|Gammaproteobacteria,1XXIV@135623|Vibrionales	135623|Vibrionales	S	Uncharacterized integral membrane protein (DUF2301)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2301
k141_3287_13	1116375.VEJY3_14565	6.5e-198	574.0	COG4232@1|root,COG4232@2|Bacteria,1MU8W@1224|Proteobacteria,1RPF7@1236|Gammaproteobacteria,1XTUK@135623|Vibrionales	135623|Vibrionales	CO	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps	dsbD	GO:0003674,GO:0003756,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0008152,GO:0009987,GO:0015035,GO:0015036,GO:0016020,GO:0016021,GO:0016043,GO:0016491,GO:0016667,GO:0016853,GO:0016860,GO:0016864,GO:0017004,GO:0019725,GO:0022607,GO:0031224,GO:0031226,GO:0034622,GO:0042592,GO:0043933,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0045454,GO:0050789,GO:0050794,GO:0055114,GO:0065003,GO:0065007,GO:0065008,GO:0071840,GO:0071944,GO:0140096	1.8.1.8	ko:K04084	-	-	-	-	ko00000,ko01000,ko03110	5.A.1.1	-	-	DsbC,DsbD,Thioredoxin_7
k141_3287_14	243277.VC_2706	2.09e-125	360.0	COG1738@1|root,COG1738@2|Bacteria,1MVQU@1224|Proteobacteria,1RNX0@1236|Gammaproteobacteria,1XV4J@135623|Vibrionales	135623|Vibrionales	U	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage	yhhQ	-	-	ko:K09125	-	-	-	-	ko00000	-	-	-	Vut_1
k141_3287_16	55601.VANGNB10_cI0187c	7.39e-44	144.0	COG1758@1|root,COG1758@2|Bacteria,1N6TX@1224|Proteobacteria,1SCSR@1236|Gammaproteobacteria,1XXX9@135623|Vibrionales	135623|Vibrionales	K	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits	rpoZ	GO:0003674,GO:0003824,GO:0003899,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576	2.7.7.6	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb6
k141_3287_17	29495.EA26_01595	0.0	1228.0	COG0317@1|root,COG0317@2|Bacteria,1MU44@1224|Proteobacteria,1RN3H@1236|Gammaproteobacteria,1XSS0@135623|Vibrionales	135623|Vibrionales	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	spoT	GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0008728,GO:0008893,GO:0009116,GO:0009117,GO:0009119,GO:0009150,GO:0009259,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0015969,GO:0016020,GO:0016740,GO:0016772,GO:0016778,GO:0016787,GO:0016788,GO:0016794,GO:0019637,GO:0019693,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0033865,GO:0033875,GO:0034032,GO:0034035,GO:0034641,GO:0042278,GO:0042578,GO:0042594,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046128,GO:0046483,GO:0050896,GO:0051716,GO:0055086,GO:0071496,GO:0071704,GO:0071944,GO:0072521,GO:1901068,GO:1901135,GO:1901360,GO:1901564,GO:1901657	2.7.6.5,3.1.7.2	ko:K01139	ko00230,map00230	-	R00336,R00429	RC00002,RC00078	ko00000,ko00001,ko01000,ko03009	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
k141_3287_18	1348635.BBJY01000009_gene1484	6.03e-132	377.0	COG0566@1|root,COG0566@2|Bacteria,1MWBE@1224|Proteobacteria,1RMPR@1236|Gammaproteobacteria,1XSPQ@135623|Vibrionales	135623|Vibrionales	J	Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA	trmH	-	2.1.1.34	ko:K00556	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylas_C,SpoU_methylase
k141_3287_19	617140.AJZE01000131_gene936	0.0	1137.0	COG1200@1|root,COG1200@2|Bacteria,1MWN2@1224|Proteobacteria,1RMMQ@1236|Gammaproteobacteria,1XUQ6@135623|Vibrionales	135623|Vibrionales	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
k141_2031_1	1304885.AUEY01000044_gene226	5.26e-116	337.0	COG2197@1|root,COG2197@2|Bacteria,1MWGM@1224|Proteobacteria,42Q40@68525|delta/epsilon subdivisions,2WKYI@28221|Deltaproteobacteria,2MJHB@213118|Desulfobacterales	28221|Deltaproteobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	ko:K02479	-	-	-	-	ko00000,ko02022	-	-	-	GerE,Response_reg
k141_1582_1	672.VV93_v1c31100	1.22e-135	404.0	COG1283@1|root,COG1283@2|Bacteria,1MUDE@1224|Proteobacteria,1RNMM@1236|Gammaproteobacteria,1XY40@135623|Vibrionales	135623|Vibrionales	P	Na+/Pi-cotransporter	-	-	-	ko:K03324	-	-	-	-	ko00000,ko02000	2.A.58.2	-	-	Na_Pi_cotrans,PhoU
k141_5023_2	29495.EA26_04095	1.12e-142	409.0	COG0583@1|root,COG0583@2|Bacteria,1MW16@1224|Proteobacteria,1RS6U@1236|Gammaproteobacteria,1XU3Y@135623|Vibrionales	135623|Vibrionales	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
k141_2937_1	155864.EDL933_0248	8.65e-132	389.0	COG5433@1|root,COG5433@2|Bacteria,1MXB5@1224|Proteobacteria,1RSAV@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Transposase	yncI	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_assoc
k141_1583_1	527002.yaldo0001_34800	5.67e-28	112.0	COG1566@1|root,COG1566@2|Bacteria,1MWG0@1224|Proteobacteria,1RRE3@1236|Gammaproteobacteria,41DH2@629|Yersinia	1236|Gammaproteobacteria	V	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	ydhJ	GO:0003674,GO:0005215,GO:0006810,GO:0006855,GO:0008150,GO:0015238,GO:0015546,GO:0015893,GO:0015906,GO:0022857,GO:0042221,GO:0042493,GO:0042886,GO:0042887,GO:0042891,GO:0042895,GO:0042908,GO:0042910,GO:0045117,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0072348,GO:1901474,GO:1901682,GO:1902599	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
k141_3288_1	1121405.dsmv_2912	2.29e-55	196.0	COG1944@1|root,COG1944@2|Bacteria,1N5NV@1224|Proteobacteria,42P09@68525|delta/epsilon subdivisions,2WK3G@28221|Deltaproteobacteria,2MMSK@213118|Desulfobacterales	28221|Deltaproteobacteria	S	YcaO cyclodehydratase, ATP-ad Mg2+-binding	-	-	-	-	-	-	-	-	-	-	-	-	YcaO
k141_4753_1	653733.Selin_0319	8.14e-42	159.0	COG0168@1|root,COG0168@2|Bacteria	2|Bacteria	P	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA	ktrB	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
k141_4753_2	1121403.AUCV01000002_gene546	6.69e-104	306.0	COG0569@1|root,COG0569@2|Bacteria,1R7KM@1224|Proteobacteria,42PJH@68525|delta/epsilon subdivisions,2WMZT@28221|Deltaproteobacteria,2MJ9H@213118|Desulfobacterales	28221|Deltaproteobacteria	P	PFAM TrkA-N domain	ktrA	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
k141_1318_1	985762.SAGN_03255	7.89e-21	95.5	COG0860@1|root,COG0860@2|Bacteria,1UYPW@1239|Firmicutes,4HBVT@91061|Bacilli,4GX8W@90964|Staphylococcaceae	91061|Bacilli	M	Probably involved in cell-wall metabolism	lytH	GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3,SH3_3
k141_1318_2	1266845.Q783_08345	5.16e-41	140.0	COG0105@1|root,COG0105@2|Bacteria,1V44G@1239|Firmicutes,4HH8C@91061|Bacilli,27GIE@186828|Carnobacteriaceae	91061|Bacilli	F	NDK	ndk	GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564	2.7.4.6	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	M00049,M00050,M00052,M00053	R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895	RC00002	ko00000,ko00001,ko00002,ko01000,ko04131	-	-	-	NDK
k141_1318_4	1121324.CLIT_11c01270	3.28e-36	125.0	COG4496@1|root,COG4496@2|Bacteria,1VA04@1239|Firmicutes,24MX9@186801|Clostridia	186801|Clostridia	S	protein, YerC YecD	-	-	-	-	-	-	-	-	-	-	-	-	Trp_repressor
k141_1318_5	1391646.AVSU01000053_gene945	6.01e-84	253.0	COG0512@1|root,COG0512@2|Bacteria,1TT9R@1239|Firmicutes,24FR0@186801|Clostridia,25QXV@186804|Peptostreptococcaceae	186801|Clostridia	EH	Peptidase C26	pabA	-	2.6.1.85,4.1.3.27	ko:K01658,ko:K01664	ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986,R01716	RC00010,RC01418,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS17720	GATase
k141_1318_6	926692.AZYG01000097_gene2334	5e-168	486.0	COG0147@1|root,COG0147@2|Bacteria,1TQAP@1239|Firmicutes,24946@186801|Clostridia,3WB6G@53433|Halanaerobiales	186801|Clostridia	EH	Anthranilate synthase component I, N terminal region	pabB	-	2.6.1.85,4.1.3.27,4.1.3.38	ko:K01657,ko:K01665,ko:K03342,ko:K13950	ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986,R01716,R05553	RC00010,RC01418,RC01843,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Anth_synt_I_N,Chorismate_bind
k141_1318_7	445973.CLOBAR_01939	1.16e-56	188.0	COG0115@1|root,COG0115@2|Bacteria,1V3JS@1239|Firmicutes,24JA5@186801|Clostridia,25SGJ@186804|Peptostreptococcaceae	186801|Clostridia	EH	Amino-transferase class IV	pabC	-	4.1.3.38	ko:K02619	ko00790,map00790	-	R05553	RC01843,RC02148	ko00000,ko00001,ko01000	-	-	-	Aminotran_4
k141_1318_8	1511.CLOST_1761	6.06e-107	311.0	COG0302@1|root,COG0302@2|Bacteria,1TRNM@1239|Firmicutes,24867@186801|Clostridia,25RGH@186804|Peptostreptococcaceae	186801|Clostridia	F	GTP cyclohydrolase I	folE	-	3.5.4.16	ko:K01495	ko00790,ko01100,map00790,map01100	M00126,M00841,M00842,M00843	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_cyclohydroI
k141_1318_9	315730.BcerKBAB4_0067	6.02e-89	272.0	COG0294@1|root,COG0294@2|Bacteria,1TPKT@1239|Firmicutes,4H9SY@91061|Bacilli,1ZAPZ@1386|Bacillus	91061|Bacilli	H	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives	folP	GO:0003674,GO:0003824,GO:0004156,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.15	ko:K00796	ko00790,ko01100,map00790,map01100	M00126,M00841	R03066,R03067	RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
k141_1318_10	349161.Dred_0155	1.88e-34	122.0	COG1539@1|root,COG1539@2|Bacteria,1VA0I@1239|Firmicutes,24MN5@186801|Clostridia,262E7@186807|Peptococcaceae	186801|Clostridia	H	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin	folB	-	1.13.11.81,4.1.2.25,5.1.99.8	ko:K01633	ko00790,ko01100,map00790,map01100	M00126,M00840	R03504,R11037,R11073	RC00721,RC00943,RC01479,RC03333,RC03334	ko00000,ko00001,ko00002,ko01000	-	-	-	FolB
k141_1318_11	500633.CLOHIR_00228	1.99e-48	169.0	COG0801@1|root,COG2876@1|root,COG0801@2|Bacteria,COG2876@2|Bacteria,1TP61@1239|Firmicutes,24812@186801|Clostridia	186801|Clostridia	E	PFAM DAHP synthetase I	aroF	-	2.5.1.54,5.4.99.5	ko:K01626,ko:K03856,ko:K13853	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	M00022,M00024,M00025	R01715,R01826	RC00435,RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_1
k141_1318_12	1408823.AXUS01000004_gene139	1.72e-120	350.0	COG2876@1|root,COG2876@2|Bacteria,1TP61@1239|Firmicutes,24812@186801|Clostridia	186801|Clostridia	E	PFAM DAHP synthetase I	aroF	-	2.5.1.54,5.4.99.5	ko:K01626,ko:K03856,ko:K13853	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	M00022,M00024,M00025	R01715,R01826	RC00435,RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_1
k141_1318_13	1121324.CLIT_11c01730	8.22e-140	425.0	COG0358@1|root,COG0358@2|Bacteria,1TQ0X@1239|Firmicutes,2480W@186801|Clostridia,25QPP@186804|Peptostreptococcaceae	186801|Clostridia	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2
k141_1318_14	1408823.AXUS01000004_gene137	2.35e-182	518.0	COG0568@1|root,COG0568@2|Bacteria,1TPD6@1239|Firmicutes,2481I@186801|Clostridia,25QZG@186804|Peptostreptococcaceae	186801|Clostridia	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	sigA	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
k141_1318_15	1408823.AXUS01000004_gene136	5.19e-58	191.0	COG2384@1|root,COG2384@2|Bacteria,1V3I4@1239|Firmicutes,24BJI@186801|Clostridia,25REY@186804|Peptostreptococcaceae	186801|Clostridia	S	tRNA (adenine(22)-N(1))-methyltransferase	trmK	-	2.1.1.217	ko:K06967	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_18,TrmK
k141_1318_16	903814.ELI_2050	2.77e-87	275.0	COG0327@1|root,COG0327@2|Bacteria,1TQ27@1239|Firmicutes,248Q2@186801|Clostridia,25W7H@186806|Eubacteriaceae	186801|Clostridia	S	dinuclear metal center protein, YbgI	-	-	-	-	-	-	-	-	-	-	-	-	NIF3
k141_1318_17	1410661.JNKW01000012_gene1265	8.72e-137	402.0	COG0116@1|root,COG0116@2|Bacteria,1TP0X@1239|Firmicutes,248MA@186801|Clostridia	186801|Clostridia	L	Belongs to the methyltransferase superfamily	ypsC	-	-	ko:K07444	-	-	-	-	ko00000,ko01000	-	-	-	THUMP,UPF0020
k141_1318_18	1215915.BN193_05115	3.12e-11	68.2	COG0406@1|root,COG0406@2|Bacteria,1VDCB@1239|Firmicutes,4HM06@91061|Bacilli,1YBI2@1357|Lactococcus	91061|Bacilli	G	Phosphoglycerate mutase family	gpmB	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
k141_1318_19	1499689.CCNN01000007_gene1371	1.02e-71	224.0	COG0283@1|root,COG0283@2|Bacteria,1V3IA@1239|Firmicutes,24HEF@186801|Clostridia,36DDB@31979|Clostridiaceae	186801|Clostridia	F	Belongs to the cytidylate kinase family. Type 1 subfamily	cmk	-	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin
k141_1318_20	350688.Clos_1562	3.97e-89	273.0	COG0761@1|root,COG0761@2|Bacteria,1UHT7@1239|Firmicutes,25E67@186801|Clostridia,36UJG@31979|Clostridiaceae	186801|Clostridia	IM	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis	ispH	-	1.17.7.4	ko:K02945,ko:K03527	ko00900,ko01100,ko01110,ko01130,ko03010,map00900,map01100,map01110,map01130,map03010	M00096,M00178	R05884,R08210	RC01137,RC01487	br01610,ko00000,ko00001,ko00002,ko01000,ko03011	-	-	-	LYTB
k141_1318_21	546269.HMPREF0389_01731	6.51e-104	317.0	COG0539@1|root,COG0539@2|Bacteria,1TQ9N@1239|Firmicutes,247UK@186801|Clostridia,25R7T@186804|Peptostreptococcaceae	186801|Clostridia	J	Ribosomal protein S1-like RNA-binding domain	ispH	-	1.17.7.4	ko:K02945,ko:K03527	ko00900,ko01100,ko01110,ko01130,ko03010,map00900,map01100,map01110,map01130,map03010	M00096,M00178	R05884,R08210	RC01137,RC01487	br01610,ko00000,ko00001,ko00002,ko01000,ko03011	-	-	-	LYTB,S1
k141_1318_22	350688.Clos_1560	7.22e-117	342.0	COG1352@1|root,COG1352@2|Bacteria,1TPD8@1239|Firmicutes,24AQJ@186801|Clostridia,36F2I@31979|Clostridiaceae	186801|Clostridia	NT	Methyltransferase	cheR	-	2.1.1.80	ko:K00575	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheR,CheR_N
k141_1318_23	420246.GTNG_1153	1.67e-46	152.0	COG2359@1|root,COG2359@2|Bacteria,1V6G8@1239|Firmicutes,4HIQV@91061|Bacilli,1WGP8@129337|Geobacillus	91061|Bacilli	S	Stage V sporulation protein S (SpoVS)	spoVS	-	-	ko:K06416	-	-	-	-	ko00000	-	-	-	SpoVS
k141_1318_24	1121324.CLIT_10c01090	4.68e-46	152.0	COG0642@1|root,COG2205@2|Bacteria,1VNVZ@1239|Firmicutes,24VI6@186801|Clostridia,25UAF@186804|Peptostreptococcaceae	186801|Clostridia	T	protein histidine kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	Usp
k141_1318_25	1111134.HMPREF1253_1088	1.26e-30	119.0	COG0491@1|root,COG0491@2|Bacteria,1V6FA@1239|Firmicutes,24JGV@186801|Clostridia,22H8Y@1570339|Peptoniphilaceae	186801|Clostridia	S	Metallo-beta-lactamase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
k141_1318_26	1408422.JHYF01000010_gene3356	3.95e-118	358.0	COG0513@1|root,COG0513@2|Bacteria,1TPAP@1239|Firmicutes,247IT@186801|Clostridia,36EYP@31979|Clostridiaceae	186801|Clostridia	L	helicase	cshA2	-	3.6.4.13	ko:K05592	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	DEAD,Helicase_C
k141_1318_27	857293.CAAU_1822	2.71e-146	420.0	COG2066@1|root,COG2066@2|Bacteria,1TP64@1239|Firmicutes,2491K@186801|Clostridia,36EFX@31979|Clostridiaceae	186801|Clostridia	E	Belongs to the glutaminase family	glsA	-	3.5.1.2	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	-	R00256,R01579	RC00010,RC02798	ko00000,ko00001,ko01000	-	-	-	Glutaminase
k141_1318_28	1304284.L21TH_0001	9.66e-68	222.0	COG0811@1|root,COG0811@2|Bacteria,1V2HH@1239|Firmicutes,24BCC@186801|Clostridia,36H09@31979|Clostridiaceae	186801|Clostridia	U	peptide transport	-	-	-	-	-	-	-	-	-	-	-	-	MotA_ExbB
k141_1318_29	1121324.CLIT_10c03400	2.74e-96	293.0	COG1360@1|root,COG1360@2|Bacteria,1UYZY@1239|Firmicutes,25D7J@186801|Clostridia	186801|Clostridia	N	OmpA family	-	-	-	ko:K02557	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	OmpA
k141_1318_30	1293054.HSACCH_01593	1.39e-43	179.0	COG4399@1|root,COG4399@2|Bacteria,1TQDH@1239|Firmicutes,24K94@186801|Clostridia,3WC4V@53433|Halanaerobiales	186801|Clostridia	S	Protein of unknown function (DUF445)	-	-	-	-	-	-	-	-	-	-	-	-	DUF445
k141_2938_1	56780.SYN_02271	1.91e-90	277.0	COG1683@1|root,COG3272@1|root,COG1683@2|Bacteria,COG3272@2|Bacteria,1MXYZ@1224|Proteobacteria,42M4E@68525|delta/epsilon subdivisions,2WKFT@28221|Deltaproteobacteria,2MQ5J@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF1722)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1722,DUF523
k141_2938_2	349124.Hhal_0058	4.07e-09	57.4	COG2200@1|root,COG2200@2|Bacteria,1MVJY@1224|Proteobacteria,1RPDW@1236|Gammaproteobacteria,1WXEM@135613|Chromatiales	135613|Chromatiales	T	PFAM EAL domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL
k141_3289_2	1116375.VEJY3_08630	1.13e-96	299.0	COG0524@1|root,COG3892@1|root,COG0524@2|Bacteria,COG3892@2|Bacteria,1MV6I@1224|Proteobacteria,1RQGH@1236|Gammaproteobacteria,1XUC3@135623|Vibrionales	135623|Vibrionales	G	Uncharacterized protein conserved in bacteria (DUF2090)	-	-	2.7.1.92	ko:K03338	ko00562,ko01100,ko01120,map00562,map01100,map01120	-	R05661	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	DUF2090,PfkB
k141_1584_1	33035.JPJF01000045_gene1023	1.58e-36	143.0	COG0624@1|root,COG0624@2|Bacteria,1TYR6@1239|Firmicutes,249CA@186801|Clostridia	186801|Clostridia	E	peptidase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
k141_1584_2	93057.EU95_1281	4.95e-35	128.0	COG1335@1|root,COG1335@2|Bacteria,1G1U0@1117|Cyanobacteria,1MMIY@1212|Prochloraceae	1117|Cyanobacteria	Q	Alternative locus ID	pncA	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase
k141_5024_1	1304885.AUEY01000018_gene1109	3.23e-193	572.0	COG2937@1|root,COG2937@2|Bacteria,1MWZ6@1224|Proteobacteria,42MN4@68525|delta/epsilon subdivisions,2WJJ5@28221|Deltaproteobacteria,2MHRG@213118|Desulfobacterales	28221|Deltaproteobacteria	I	Belongs to the GPAT DAPAT family	plsB	-	2.3.1.15	ko:K00631	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
k141_5024_2	1121405.dsmv_1455	4.7e-40	152.0	COG1208@1|root,COG3178@1|root,COG1208@2|Bacteria,COG3178@2|Bacteria,1MXCH@1224|Proteobacteria,42N6V@68525|delta/epsilon subdivisions,2WIQC@28221|Deltaproteobacteria,2MI45@213118|Desulfobacterales	28221|Deltaproteobacteria	JM	PFAM aminoglycoside phosphotransferase	-	-	2.7.1.221	ko:K07102	ko00520,ko01100,map00520,map01100	-	R08968,R11024	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	APH,NTP_transferase
k141_5025_1	1265505.ATUG01000003_gene883	6.13e-28	113.0	COG2070@1|root,COG2070@2|Bacteria,1MWMI@1224|Proteobacteria,42P2I@68525|delta/epsilon subdivisions,2WK0M@28221|Deltaproteobacteria,2MIJJ@213118|Desulfobacterales	28221|Deltaproteobacteria	S	TIGRFAM PfaD family protein	-	-	-	-	-	-	-	-	-	-	-	-	NMO
k141_2032_1	1348635.BBJY01000006_gene449	1.25e-87	266.0	COG2207@1|root,COG2207@2|Bacteria,1R4RI@1224|Proteobacteria,1RZFI@1236|Gammaproteobacteria,1XX1W@135623|Vibrionales	135623|Vibrionales	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
k141_2032_2	596151.DesfrDRAFT_0675	2.37e-16	73.9	COG0251@1|root,COG0251@2|Bacteria,1RH61@1224|Proteobacteria,431UE@68525|delta/epsilon subdivisions,2WWKK@28221|Deltaproteobacteria,2MBP1@213115|Desulfovibrionales	28221|Deltaproteobacteria	J	Endoribonuclease L-PSP	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
k141_2032_3	932677.PAJ_0976	3.78e-96	290.0	COG0673@1|root,COG0673@2|Bacteria,1MVVF@1224|Proteobacteria,1RMKA@1236|Gammaproteobacteria,3VYQA@53335|Pantoea	1236|Gammaproteobacteria	S	oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
k141_2032_4	1219077.VAZ01S_025_00060	9.65e-62	196.0	COG0454@1|root,COG0456@2|Bacteria,1QAX9@1224|Proteobacteria,1T6CW@1236|Gammaproteobacteria,1Y1IG@135623|Vibrionales	135623|Vibrionales	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_2032_6	1190603.AJYD01000004_gene4232	1.16e-81	261.0	COG1167@1|root,COG1167@2|Bacteria,1MUJE@1224|Proteobacteria,1RXYA@1236|Gammaproteobacteria,1XVSK@135623|Vibrionales	135623|Vibrionales	K	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2,GntR
k141_4754_1	1121396.KB893062_gene2776	1.19e-245	690.0	COG4650@1|root,COG4650@2|Bacteria,1MX6U@1224|Proteobacteria,42NHB@68525|delta/epsilon subdivisions,2WKUB@28221|Deltaproteobacteria,2MMWE@213118|Desulfobacterales	28221|Deltaproteobacteria	KT	Regulator of RNA terminal phosphate cyclase	rtcR	-	-	ko:K14414	-	-	-	-	ko00000,ko03000	-	-	-	RtcR,Sigma54_activat
k141_4754_2	879212.DespoDRAFT_00985	1.26e-12	69.7	COG4804@1|root,COG4804@2|Bacteria,1NBWK@1224|Proteobacteria,42NXR@68525|delta/epsilon subdivisions,2WN7B@28221|Deltaproteobacteria,2MN5N@213118|Desulfobacterales	28221|Deltaproteobacteria	V	Protein of unknown function (DUF1016)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1016
k141_5026_1	1121405.dsmv_0918	4.37e-121	353.0	COG1024@1|root,COG1024@2|Bacteria,1MWZC@1224|Proteobacteria,42QPM@68525|delta/epsilon subdivisions,2WMRG@28221|Deltaproteobacteria,2MI75@213118|Desulfobacterales	28221|Deltaproteobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	4.2.1.17	ko:K01715	ko00650,ko01200,map00650,map01200	-	R03026	RC00831	ko00000,ko00001,ko01000	-	-	iAF987.Gmet_1716	ECH_1
k141_2621_1	1191299.AJYX01000067_gene3835	2.64e-148	428.0	COG0141@1|root,COG0141@2|Bacteria,1MUUF@1224|Proteobacteria,1RMZD@1236|Gammaproteobacteria,1XTSW@135623|Vibrionales	135623|Vibrionales	E	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine	hisD	GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.23	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01158,R01163,R03012	RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000	-	-	-	Histidinol_dh
k141_2621_3	1348635.BBJY01000004_gene3001	5.76e-262	731.0	COG1757@1|root,COG1757@2|Bacteria,1MY5C@1224|Proteobacteria,1RP6I@1236|Gammaproteobacteria,1XSDA@135623|Vibrionales	135623|Vibrionales	C	COG1757 Na H antiporter	-	-	-	ko:K18218	-	M00667	-	-	ko00000,ko00002,ko01504,ko02000	-	-	-	Na_H_antiporter
k141_4755_1	1304885.AUEY01000028_gene2821	5e-82	251.0	COG1024@1|root,COG1024@2|Bacteria,1MWZC@1224|Proteobacteria,42QPM@68525|delta/epsilon subdivisions,2WMRG@28221|Deltaproteobacteria,2MI75@213118|Desulfobacterales	28221|Deltaproteobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	4.2.1.17	ko:K01715	ko00650,ko01200,map00650,map01200	-	R03026	RC00831	ko00000,ko00001,ko01000	-	-	iAF987.Gmet_1716	ECH_1
k141_1586_1	1304885.AUEY01000082_gene2156	8.03e-109	325.0	COG4977@1|root,COG4977@2|Bacteria,1MUDK@1224|Proteobacteria,42QRG@68525|delta/epsilon subdivisions,2WJ5Z@28221|Deltaproteobacteria,2MIYW@213118|Desulfobacterales	28221|Deltaproteobacteria	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	DJ-1_PfpI,HTH_18
k141_5027_1	1304885.AUEY01000014_gene3350	2.33e-19	87.0	COG4262@1|root,COG4262@2|Bacteria,1QTYC@1224|Proteobacteria,42N8N@68525|delta/epsilon subdivisions,2WKR3@28221|Deltaproteobacteria,2MIDS@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	speE	-	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	Spermine_synth
k141_5027_2	1304885.AUEY01000014_gene3349	2.27e-105	313.0	COG3766@1|root,COG3766@2|Bacteria,1Q8XV@1224|Proteobacteria,42M8R@68525|delta/epsilon subdivisions,2WMH7@28221|Deltaproteobacteria,2MII9@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Domain of Unknown Function (DUF350)	-	-	-	-	-	-	-	-	-	-	-	-	DUF350
k141_4756_1	1136163.M565_ctg1P1923	7.62e-30	121.0	COG1570@1|root,COG1570@2|Bacteria,1MUA4@1224|Proteobacteria,1RNAZ@1236|Gammaproteobacteria,1XSYD@135623|Vibrionales	135623|Vibrionales	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseA	GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008855,GO:0009056,GO:0009057,GO:0009318,GO:0009987,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0019439,GO:0032991,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575,GO:1902494	3.1.11.6	ko:K03601	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
k141_2622_1	879212.DespoDRAFT_01426	1.57e-29	107.0	2E79S@1|root,331TB@2|Bacteria,1NABI@1224|Proteobacteria,42V7R@68525|delta/epsilon subdivisions,2WRM1@28221|Deltaproteobacteria,2MKFF@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_2622_2	1304885.AUEY01000026_gene3549	1.24e-77	241.0	COG0517@1|root,COG0794@1|root,COG0517@2|Bacteria,COG0794@2|Bacteria,1MUXD@1224|Proteobacteria,42M0M@68525|delta/epsilon subdivisions,2WJ4Y@28221|Deltaproteobacteria,2MIJI@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Belongs to the SIS family. GutQ KpsF subfamily	kpsF	-	5.3.1.13	ko:K06041	ko00540,ko01100,map00540,map01100	M00063	R01530	RC00541	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CBS,SIS
k141_2033_1	645991.Sgly_1820	1.05e-11	73.2	COG2207@1|root,COG2207@2|Bacteria,1VEW5@1239|Firmicutes	1239|Firmicutes	K	Transcriptional regulator (AraC family)	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
k141_1320_1	1304885.AUEY01000025_gene2768	1.7e-279	789.0	COG0243@1|root,COG0243@2|Bacteria,1NR6J@1224|Proteobacteria,42NEV@68525|delta/epsilon subdivisions,2WJD0@28221|Deltaproteobacteria,2MMR0@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Molybdopterin oxidoreductase Fe4S4 domain	-	-	-	-	-	-	-	-	-	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
k141_1320_2	1304885.AUEY01000090_gene2887	1.1e-106	331.0	COG0303@1|root,COG2191@1|root,COG0303@2|Bacteria,COG2191@2|Bacteria,1MYKY@1224|Proteobacteria,42NIJ@68525|delta/epsilon subdivisions,2WJ0M@28221|Deltaproteobacteria,2MPIP@213118|Desulfobacterales	28221|Deltaproteobacteria	CH	FmdE, Molybdenum formylmethanofuran dehydrogenase operon	-	-	1.2.7.12	ko:K11261	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00567	R03015,R08060,R11743	RC00197,RC00323	ko00000,ko00001,ko00002,ko01000	-	-	-	FmdE,MoCF_biosynth
k141_1587_1	644282.Deba_1310	1.46e-27	117.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42N03@68525|delta/epsilon subdivisions,2WIX4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	NT	PFAM chemotaxis sensory transducer	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HBM,MCPsignal
k141_663_1	55601.VANGNB10_cI2377c	2.69e-215	597.0	COG0180@1|root,COG0180@2|Bacteria,1MV4T@1224|Proteobacteria,1RNDC@1236|Gammaproteobacteria,1XUUG@135623|Vibrionales	135623|Vibrionales	J	Tryptophanyl-tRNA synthetase	trpS	GO:0003674,GO:0003824,GO:0004812,GO:0004830,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006436,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
k141_663_2	338963.Pcar_1478	7.82e-37	138.0	COG1418@1|root,COG1418@2|Bacteria,1RK7K@1224|Proteobacteria,42SRK@68525|delta/epsilon subdivisions,2WP5I@28221|Deltaproteobacteria,43UQH@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Metal-dependent phosphohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HD
k141_663_3	1283284.AZUK01000001_gene1385	5.6e-24	91.7	2991E@1|root,2ZW4Z@2|Bacteria,1PB6X@1224|Proteobacteria,1SW7E@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	VPA0114	-	-	-	-	-	-	-	-	-	-	-	-
k141_663_4	400668.Mmwyl1_2937	5.9e-69	209.0	COG3169@1|root,COG3169@2|Bacteria,1RHBQ@1224|Proteobacteria,1S7UR@1236|Gammaproteobacteria,1XKEA@135619|Oceanospirillales	135619|Oceanospirillales	S	Putative member of DMT superfamily (DUF486)	-	-	-	ko:K09922	-	-	-	-	ko00000	-	-	-	DMT_6
k141_663_5	223926.28807808	2.99e-115	332.0	COG0512@1|root,COG0512@2|Bacteria,1MV5Y@1224|Proteobacteria,1RMQW@1236|Gammaproteobacteria,1XUV5@135623|Vibrionales	135623|Vibrionales	EH	COG0512 Anthranilate para-aminobenzoate synthases component II	pabA	-	2.6.1.85	ko:K01664	ko00790,map00790	-	R01716	RC00010,RC01418	ko00000,ko00001,ko01000	-	-	-	GATase
k141_663_6	1238450.VIBNISOn1_590016	1.15e-249	690.0	COG4992@1|root,COG4992@2|Bacteria,1MV3C@1224|Proteobacteria,1RMV1@1236|Gammaproteobacteria,1XSTJ@135623|Vibrionales	135623|Vibrionales	E	acetylornithine aminotransferase	argD	GO:0003674,GO:0003824,GO:0003992,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
k141_663_7	1517681.HW45_26990	4.45e-183	516.0	COG3138@1|root,COG3138@2|Bacteria,1MWHC@1224|Proteobacteria,1RMXG@1236|Gammaproteobacteria,1XSR5@135623|Vibrionales	135623|Vibrionales	H	COG3138 Arginine ornithine N-succinyltransferase beta subunit	astA	-	2.3.1.109	ko:K00673	ko00330,ko01100,map00330,map01100	-	R00832	RC00004,RC00064	ko00000,ko00001,ko01000	-	-	-	AstA
k141_664_70	55601.VANGNB10_cI0872	1.41e-210	592.0	COG0285@1|root,COG0285@2|Bacteria,1MVCH@1224|Proteobacteria,1RMB0@1236|Gammaproteobacteria,1XSGS@135623|Vibrionales	135623|Vibrionales	H	Belongs to the folylpolyglutamate synthase family	folC	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_C,Mur_ligase_M
k141_664_71	1219077.VAZ01S_018_00320	3.35e-183	514.0	COG0777@1|root,COG0777@2|Bacteria,1MW8G@1224|Proteobacteria,1RNDS@1236|Gammaproteobacteria,1XUF4@135623|Vibrionales	135623|Vibrionales	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA	accD	GO:0003674,GO:0003824,GO:0003989,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009317,GO:0009987,GO:0016053,GO:0016421,GO:0016874,GO:0016885,GO:0019752,GO:0032787,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901576,GO:1902494	2.1.3.15,6.4.1.2	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
k141_5093_1	1265505.ATUG01000001_gene4095	3.49e-104	308.0	COG1250@1|root,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,42M6J@68525|delta/epsilon subdivisions,2WJZQ@28221|Deltaproteobacteria,2MJ78@213118|Desulfobacterales	28221|Deltaproteobacteria	I	PFAM 3-hydroxyacyl-CoA dehydrogenase	mmgB	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
k141_4059_1	1304885.AUEY01000094_gene3535	1.41e-79	243.0	29CZA@1|root,2ZZXB@2|Bacteria,1RFNE@1224|Proteobacteria,42TRV@68525|delta/epsilon subdivisions,2WR3X@28221|Deltaproteobacteria,2MKTT@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_4059_2	658187.LDG_7098	1.43e-14	78.2	COG4221@1|root,COG4221@2|Bacteria,1R1DK@1224|Proteobacteria,1T4YM@1236|Gammaproteobacteria,1JFTC@118969|Legionellales	118969|Legionellales	S	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
k141_665_1	457405.FSDG_00462	1.06e-08	65.5	COG2067@1|root,COG2067@2|Bacteria,37964@32066|Fusobacteria	32066|Fusobacteria	I	Outer membrane protein transport protein (OMPP1 FadL TodX)	-	-	-	ko:K06076	-	-	-	-	ko00000,ko02000	1.B.9	-	-	Toluene_X
k141_666_1	879212.DespoDRAFT_00894	1.65e-99	302.0	COG0412@1|root,COG0412@2|Bacteria,1R3DI@1224|Proteobacteria	1224|Proteobacteria	Q	Dienelactone hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	DLH
k141_666_2	1348635.BBJY01000004_gene3124	6.48e-14	66.2	2EGA9@1|root,33A23@2|Bacteria,1NI0T@1224|Proteobacteria,1SH37@1236|Gammaproteobacteria,1XZKP@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_5094_1	675816.VIA_001392	2.26e-70	220.0	COG0847@1|root,COG0847@2|Bacteria,1RAF1@1224|Proteobacteria,1S20V@1236|Gammaproteobacteria,1XSA6@135623|Vibrionales	135623|Vibrionales	L	COG0847 DNA polymerase III, epsilon subunit and related 3'-5' exonucleases	-	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	RNase_T
k141_5094_2	1348635.BBJY01000015_gene718	0.0	942.0	COG2905@1|root,COG2905@2|Bacteria,1MW8U@1224|Proteobacteria,1RPSJ@1236|Gammaproteobacteria,1XSDF@135623|Vibrionales	135623|Vibrionales	T	containing cAMP-binding and CBS domains	-	-	-	ko:K07182	-	-	-	-	ko00000	-	-	-	CBS,DUF294,DUF294_C,cNMP_binding
k141_5094_3	1410618.JNKI01000001_gene1434	6.88e-75	243.0	COG0477@1|root,COG2814@2|Bacteria,1TQHD@1239|Firmicutes,4H2AI@909932|Negativicutes	909932|Negativicutes	EGP	Major Facilitator	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
k141_4336_2	617140.AJZE01000008_gene3471	3.43e-92	271.0	COG3090@1|root,COG3090@2|Bacteria,1QETR@1224|Proteobacteria,1TBPX@1236|Gammaproteobacteria,1XYZ5@135623|Vibrionales	135623|Vibrionales	G	Tripartite ATP-independent periplasmic transporters, DctQ component	-	-	-	ko:K21394	-	-	-	-	ko00000,ko02000	2.A.56.1	-	-	DctQ
k141_4336_3	617140.AJZE01000008_gene3470	4.71e-218	604.0	COG2055@1|root,COG2055@2|Bacteria,1MWQY@1224|Proteobacteria,1RSGK@1236|Gammaproteobacteria,1Y25C@135623|Vibrionales	135623|Vibrionales	C	Malate/L-lactate dehydrogenase	-	-	1.1.1.130	ko:K08092	ko00040,ko00053,map00040,map00053	-	R02637,R02639	RC00238	ko00000,ko00001,ko01000	-	-	-	Ldh_2
k141_5116_13	1123288.SOV_3c05970	2.58e-36	143.0	COG2984@1|root,COG2984@2|Bacteria,1VCBZ@1239|Firmicutes	1239|Firmicutes	S	ABC transporter substrate binding protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC_sub_bind
k141_5116_14	177437.HRM2_02090	3.63e-48	191.0	COG0477@1|root,COG2814@2|Bacteria,1MXKN@1224|Proteobacteria,42MP0@68525|delta/epsilon subdivisions,2WJWI@28221|Deltaproteobacteria,2MHZI@213118|Desulfobacterales	28221|Deltaproteobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
k141_5116_16	1157490.EL26_15070	1.14e-134	421.0	COG0464@1|root,COG0464@2|Bacteria,1TQXY@1239|Firmicutes,4HCJY@91061|Bacilli	91061|Bacilli	O	ATPase family associated with various cellular activities (AAA)	-	-	-	-	-	-	-	-	-	-	-	-	AAA
k141_5116_17	553973.CLOHYLEM_06213	1.84e-21	94.0	2E7AK@1|root,32CDW@2|Bacteria,1TYNM@1239|Firmicutes,2586X@186801|Clostridia,22349@1506553|Lachnoclostridium	186801|Clostridia	S	Protein of unknown function (DUF4255)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4255
k141_5116_20	555079.Toce_0183	1.08e-27	105.0	COG0640@1|root,COG0640@2|Bacteria,1VEER@1239|Firmicutes,25B8J@186801|Clostridia,42JEC@68295|Thermoanaerobacterales	186801|Clostridia	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5
k141_5116_21	1582152.A0A0A8WJI9_9CAUD	4.06e-44	151.0	4QCT7@10239|Viruses,4QPFU@28883|Caudovirales,4QIIN@10662|Myoviridae	10662|Myoviridae	S	4 iron, 4 sulfur cluster binding	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_5116_22	1292035.H476_3395	0.0	1197.0	COG1328@1|root,COG1328@2|Bacteria,1TR9K@1239|Firmicutes,247WF@186801|Clostridia,25QKN@186804|Peptostreptococcaceae	186801|Clostridia	F	Anaerobic ribonucleoside-triphosphate reductase	nrdD	-	1.1.98.6	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R11633,R11634,R11635,R11636	RC00613	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-cone,NRDD
k141_5116_23	1391646.AVSU01000047_gene1583	2.87e-206	588.0	COG1492@1|root,COG1492@2|Bacteria,1TP5E@1239|Firmicutes,248XW@186801|Clostridia,25QXP@186804|Peptostreptococcaceae	186801|Clostridia	H	Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation	cobQ	-	6.3.5.10	ko:K02232	ko00860,ko01100,map00860,map01100	M00122	R05225	RC00010,RC01302	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS15780	AAA_26,CbiA,GATase_3
k141_5116_24	1408823.AXUS01000033_gene2826	9.72e-150	436.0	COG0436@1|root,COG0436@2|Bacteria,1TP0J@1239|Firmicutes,247NQ@186801|Clostridia,25QZN@186804|Peptostreptococcaceae	186801|Clostridia	E	Aminotransferase	aspC	-	2.6.1.1	ko:K00812,ko:K10907	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
k141_5116_26	1511.CLOST_0952	2.95e-283	783.0	COG1190@1|root,COG1190@2|Bacteria,1TP2P@1239|Firmicutes,247VX@186801|Clostridia,25QCN@186804|Peptostreptococcaceae	186801|Clostridia	J	Belongs to the class-II aminoacyl-tRNA synthetase family	lysS	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon,tRNA_bind
k141_5116_27	1391646.AVSU01000035_gene2112	1.27e-70	217.0	COG0782@1|root,COG0782@2|Bacteria,1V44S@1239|Firmicutes,24HP9@186801|Clostridia,25RD0@186804|Peptostreptococcaceae	186801|Clostridia	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	-	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
k141_5116_28	1151292.QEW_4184	1.29e-124	367.0	COG0042@1|root,COG0042@2|Bacteria,1TQ2R@1239|Firmicutes,248HD@186801|Clostridia,25QSU@186804|Peptostreptococcaceae	186801|Clostridia	H	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	dus	-	-	ko:K05540	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Dus
k141_5116_29	1286171.EAL2_c17920	1.38e-135	389.0	COG1521@1|root,COG1521@2|Bacteria,1TR0X@1239|Firmicutes,248PX@186801|Clostridia,25VB2@186806|Eubacteriaceae	186801|Clostridia	H	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis	coaX	-	2.7.1.33	ko:K03525	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Pan_kinase
k141_5116_30	999411.HMPREF1092_01928	7.39e-46	157.0	COG4684@1|root,COG4684@2|Bacteria,1V2M1@1239|Firmicutes,249YQ@186801|Clostridia,36DT8@31979|Clostridiaceae	186801|Clostridia	S	ECF transporter, substrate-specific component	-	-	-	-	-	-	-	-	-	-	-	-	ECF_trnsprt
k141_5116_31	634498.mru_1708	6.48e-34	132.0	COG1173@1|root,arCOG00748@2157|Archaea,2XUIX@28890|Euryarchaeota,23PCT@183925|Methanobacteria	183925|Methanobacteria	E	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
k141_5116_32	1452536.JARE01000042_gene86	3.65e-06	56.6	COG0601@1|root,COG0601@2|Bacteria,2GM72@201174|Actinobacteria,4FR9G@85023|Microbacteriaceae	201174|Actinobacteria	EP	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
k141_5116_33	1042156.CXIVA_06140	3.18e-141	424.0	COG0747@1|root,COG0747@2|Bacteria,1TQ0N@1239|Firmicutes,25CDM@186801|Clostridia,36EUU@31979|Clostridiaceae	186801|Clostridia	E	family 5	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
k141_5116_34	1511.CLOST_0947	3.07e-123	363.0	COG3191@1|root,COG3191@2|Bacteria,1TP60@1239|Firmicutes,24AVR@186801|Clostridia,25R4E@186804|Peptostreptococcaceae	186801|Clostridia	EQ	Peptidase family S58	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S58
k141_5116_35	997296.PB1_13899	1.01e-69	227.0	COG0340@1|root,COG1654@1|root,COG0340@2|Bacteria,COG1654@2|Bacteria,1TQCU@1239|Firmicutes,4HB60@91061|Bacilli,1ZBI9@1386|Bacillus	91061|Bacilli	K	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor	birA	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_C,BPL_LplA_LipB,HTH_11
k141_5116_36	1511.CLOST_0945	4.54e-203	572.0	COG1883@1|root,COG1883@2|Bacteria,1TPEP@1239|Firmicutes,248ET@186801|Clostridia	186801|Clostridia	C	decarboxylase beta subunit	gcdB	-	4.1.1.3	ko:K01572	ko00620,ko01100,map00620,map01100	-	R00217	RC00040	ko00000,ko00001,ko01000,ko02000	3.B.1.1.1	-	-	OAD_beta
k141_5116_37	1501391.LG35_01735	2.85e-10	62.0	COG4770@1|root,COG4770@2|Bacteria,4NSWV@976|Bacteroidetes,2FRYI@200643|Bacteroidia,22UGJ@171550|Rikenellaceae	976|Bacteroidetes	I	Biotin-requiring enzyme	mmdC	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl
k141_5116_38	1511.CLOST_0943	1.02e-19	85.9	COG3630@1|root,COG3630@2|Bacteria,1VKW0@1239|Firmicutes,24VA0@186801|Clostridia	186801|Clostridia	C	decarboxylase, gamma subunit	-	-	-	-	-	-	-	-	-	-	-	-	OAD_gamma
k141_5116_39	1408422.JHYF01000006_gene1278	1.12e-294	813.0	COG4799@1|root,COG4799@2|Bacteria,1TQCV@1239|Firmicutes,247WG@186801|Clostridia,36E1X@31979|Clostridiaceae	186801|Clostridia	I	Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)	yqjD	-	2.1.3.15,6.4.1.3	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	M00373,M00741	R01859	RC00097,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
k141_5116_40	1476973.JMMB01000007_gene1301	2.2e-75	229.0	COG0346@1|root,COG0346@2|Bacteria,1V6SC@1239|Firmicutes,24HPI@186801|Clostridia,25T50@186804|Peptostreptococcaceae	186801|Clostridia	E	Glyoxalase-like domain	mce	-	4.4.1.5,5.1.99.1	ko:K01759,ko:K05606	ko00280,ko00620,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00620,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R02530,R02765,R09979	RC00004,RC00740,RC00780,RC02739	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase_4
k141_5116_41	1391646.AVSU01000043_gene1438	2.66e-146	421.0	COG1703@1|root,COG1703@2|Bacteria,1TQT4@1239|Firmicutes,24944@186801|Clostridia,25SGB@186804|Peptostreptococcaceae	186801|Clostridia	E	ArgK protein	argK	-	-	ko:K07588	-	-	-	-	ko00000,ko01000	-	-	-	ArgK
k141_5116_42	1408422.JHYF01000006_gene1275	2.16e-79	237.0	COG2185@1|root,COG2185@2|Bacteria,1V3QN@1239|Firmicutes,24HAR@186801|Clostridia,36J94@31979|Clostridiaceae	186801|Clostridia	I	B12 binding domain	-	-	5.4.99.2	ko:K01849	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding
k141_5116_43	1511.CLOST_0938	3.04e-312	861.0	COG1884@1|root,COG1884@2|Bacteria,1TQAD@1239|Firmicutes,24BDK@186801|Clostridia	186801|Clostridia	I	PFAM Methylmalonyl-CoA mutase	-	-	5.4.99.2	ko:K01847,ko:K01848	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
k141_5116_45	1476973.JMMB01000007_gene1297	3.98e-280	775.0	COG0427@1|root,COG0427@2|Bacteria,1TPHC@1239|Firmicutes,247V0@186801|Clostridia,25SH7@186804|Peptostreptococcaceae	186801|Clostridia	C	Acetyl-CoA hydrolase/transferase N-terminal domain	-	-	2.8.3.18	ko:K18118	ko00020,ko00620,ko00650,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00650,map01100,map01110,map01120,map01130,map01200	M00009,M00011	R10343	RC00012,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	AcetylCoA_hyd_C,AcetylCoA_hydro
k141_5116_46	1121289.JHVL01000048_gene893	3.72e-32	115.0	2CKNI@1|root,32SCP@2|Bacteria,1VCRC@1239|Firmicutes,24QX2@186801|Clostridia,36NU6@31979|Clostridiaceae	186801|Clostridia	S	Domain of unknown function (DUF3870)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3870
k141_5116_47	1121289.JHVL01000048_gene892	3.58e-206	584.0	COG2985@1|root,COG2985@2|Bacteria,1TT3J@1239|Firmicutes,24AC4@186801|Clostridia,36F5N@31979|Clostridiaceae	186801|Clostridia	S	Predicted Permease Membrane Region	-	-	-	ko:K07085	-	-	-	-	ko00000	2.A.81	-	-	Asp-Al_Ex
k141_5116_48	1121324.CLIT_13c02400	0.0	886.0	COG0465@1|root,COG0465@2|Bacteria,1TPTV@1239|Firmicutes,247WQ@186801|Clostridia,25QQY@186804|Peptostreptococcaceae	186801|Clostridia	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
k141_5116_49	1511.CLOST_0936	6.68e-152	447.0	COG0037@1|root,COG0037@2|Bacteria,1TPXP@1239|Firmicutes,248TY@186801|Clostridia,25QZ7@186804|Peptostreptococcaceae	186801|Clostridia	D	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	6.3.4.19	ko:K04075	-	-	R09597	RC02633,RC02634	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3,TilS,TilS_C
k141_4464_4	574087.Acear_0672	5.3e-50	166.0	COG0701@1|root,COG0701@2|Bacteria,1V917@1239|Firmicutes,24MFJ@186801|Clostridia,3WBRQ@53433|Halanaerobiales	186801|Clostridia	S	Predicted permease	-	-	-	-	-	-	-	-	-	-	-	-	ArsP_1
k141_5122_2	265072.Mfla_2717	2.95e-36	136.0	COG3267@1|root,COG3267@2|Bacteria,1MU3G@1224|Proteobacteria,2VIZF@28216|Betaproteobacteria	28216|Betaproteobacteria	U	AAA domain	exeA	-	-	ko:K02450,ko:K12283	-	M00331	-	-	ko00000,ko00002,ko02044	9.B.42	-	-	AAA_22
k141_2407_1	163908.KB235896_gene4898	1.12e-154	501.0	COG0500@1|root,COG3321@1|root,COG2226@2|Bacteria,COG3321@2|Bacteria,1FZXE@1117|Cyanobacteria,1HIGN@1161|Nostocales	1117|Cyanobacteria	CQ	acyl transferase domain	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N_2,AMP-binding,AMP-binding_C,Acyl_transf_1,Condensation,KAsynt_C_assoc,KR,Ketoacyl-synt_C,Methyltransf_12,PP-binding,PS-DH,Thioesterase,ketoacyl-synt
k141_5123_1	443144.GM21_0945	3.4e-57	193.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,42M2A@68525|delta/epsilon subdivisions,2WJ41@28221|Deltaproteobacteria,43T6U@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	PFAM ABC transporter related	ybiT	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,ABC_tran_Xtn
k141_5123_2	398767.Glov_3011	4.27e-10	59.7	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,42M2A@68525|delta/epsilon subdivisions,2WJ41@28221|Deltaproteobacteria,43T6U@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	PFAM ABC transporter related	ybiT	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,ABC_tran_Xtn
k141_94_2	675806.VII_002367	1.45e-17	85.5	COG3673@1|root,COG3673@2|Bacteria,1QV8K@1224|Proteobacteria,1T29Z@1236|Gammaproteobacteria,1XV7E@135623|Vibrionales	135623|Vibrionales	S	Uncharacterized alpha/beta hydrolase domain (DUF2235)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2235
k141_4796_1	1304885.AUEY01000004_gene937	3.38e-33	138.0	COG3437@1|root,COG3437@2|Bacteria,1QUN9@1224|Proteobacteria,42PB6@68525|delta/epsilon subdivisions,2WJJ9@28221|Deltaproteobacteria,2MHWZ@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Domain of unknown function (DUF3369)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3369,HD,Response_reg
k141_734_2	1121396.KB892902_gene2283	5.58e-123	362.0	COG1181@1|root,COG1181@2|Bacteria,1MUTB@1224|Proteobacteria,42NF2@68525|delta/epsilon subdivisions,2WJ7Q@28221|Deltaproteobacteria,2MI9U@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Belongs to the D-alanine--D-alanine ligase family	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
k141_734_3	1443125.Z962_06510	3.62e-34	130.0	COG0046@1|root,COG0047@1|root,COG0151@1|root,COG0046@2|Bacteria,COG0047@2|Bacteria,COG0151@2|Bacteria,1TPAS@1239|Firmicutes,247W2@186801|Clostridia,36UJE@31979|Clostridiaceae	186801|Clostridia	F	phosphoribosylformylglycinamidine synthase	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C,GATase_5
k141_4797_1	1410653.JHVC01000010_gene3528	5.07e-06	47.8	COG0786@1|root,COG0786@2|Bacteria,1TS2B@1239|Firmicutes,24CRX@186801|Clostridia,36EU3@31979|Clostridiaceae	186801|Clostridia	E	glutamate:sodium symporter activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_95_1	945550.VISI1226_19911	2.82e-12	70.9	COG2091@1|root,COG2091@2|Bacteria,1NPFV@1224|Proteobacteria	1224|Proteobacteria	H	polysaccharide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_3772_1	29495.EA26_11270	5.88e-25	96.7	COG3118@1|root,COG3118@2|Bacteria,1RHUA@1224|Proteobacteria,1S64W@1236|Gammaproteobacteria,1XWV6@135623|Vibrionales	135623|Vibrionales	O	COG0526 Thiol-disulfide isomerase and thioredoxins	trxC	-	1.8.1.8	ko:K03672	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Thioredoxin
k141_3772_2	675813.VIB_002390	8.21e-49	157.0	COG2926@1|root,COG2926@2|Bacteria,1RH0U@1224|Proteobacteria,1S6XT@1236|Gammaproteobacteria,1XXYA@135623|Vibrionales	135623|Vibrionales	S	Belongs to the UPF0265 family	-	-	-	ko:K09802	-	-	-	-	ko00000	-	-	-	DUF496
k141_3772_4	55601.VANGNB10_cII0702c	3.84e-93	278.0	COG3132@1|root,COG3132@2|Bacteria,1RA13@1224|Proteobacteria,1RQUQ@1236|Gammaproteobacteria,1XUQY@135623|Vibrionales	135623|Vibrionales	S	Belongs to the UPF0502 family	yceH	-	-	ko:K09915	-	-	-	-	ko00000	-	-	-	DUF480
k141_3772_5	1188252.AJYK01000033_gene1073	4.26e-27	102.0	COG2827@1|root,COG2827@2|Bacteria,1N6PA@1224|Proteobacteria,1SCBH@1236|Gammaproteobacteria,1XYY3@135623|Vibrionales	135623|Vibrionales	L	endonuclease containing a URI domain	yhbQ	-	-	ko:K07461	-	-	-	-	ko00000	-	-	-	GIY-YIG
k141_3772_6	1348635.BBJY01000014_gene872	1.65e-160	460.0	COG1879@1|root,COG1879@2|Bacteria,1NKCW@1224|Proteobacteria,1RT5N@1236|Gammaproteobacteria,1XV03@135623|Vibrionales	135623|Vibrionales	G	COG1879 ABC-type sugar transport system, periplasmic component	luxP	GO:0006355,GO:0006810,GO:0008150,GO:0008643,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051179,GO:0051234,GO:0051252,GO:0060255,GO:0065007,GO:0071702,GO:0080090,GO:1903506,GO:2000112,GO:2001141	-	ko:K10910	ko02020,ko02024,ko05111,map02020,map02024,map05111	-	-	-	ko00000,ko00001	-	-	-	Peripla_BP_4
k141_3772_7	575788.VS_II0356	3.88e-122	393.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1N96D@1224|Proteobacteria,1T1YZ@1236|Gammaproteobacteria,1Y339@135623|Vibrionales	135623|Vibrionales	T	COG0642 Signal transduction histidine kinase	luxQ	-	2.7.13.3	ko:K10909	ko02020,ko02024,ko05111,map02020,map02024,map05111	M00513	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,LuxQ-periplasm,Response_reg
k141_3772_8	945550.VISI1226_16118	5.18e-41	146.0	2DMZT@1|root,32UNF@2|Bacteria,1N84C@1224|Proteobacteria,1S9M2@1236|Gammaproteobacteria,1XWT1@135623|Vibrionales	135623|Vibrionales	S	Flagellar protein YcgR	-	-	-	-	-	-	-	-	-	-	-	-	PilZ,YcgR_2
k141_3772_9	870967.VIS19158_03387	3.97e-53	173.0	2B0QJ@1|root,31MNT@2|Bacteria,1QJGF@1224|Proteobacteria,1THG6@1236|Gammaproteobacteria,1XVJQ@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_3772_10	55601.VANGNB10_cII0675c	2.46e-256	713.0	COG1492@1|root,COG1492@2|Bacteria,1MUFY@1224|Proteobacteria,1RP8G@1236|Gammaproteobacteria,1XV2B@135623|Vibrionales	135623|Vibrionales	H	Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation	cobQ	GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042364,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.5.10	ko:K02232	ko00860,ko01100,map00860,map01100	M00122	R05225	RC00010,RC01302	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_26,CbiA,GATase_3
k141_3772_11	1187848.AJYQ01000090_gene2772	1.91e-14	70.5	2AWP7@1|root,31NK4@2|Bacteria,1QKAT@1224|Proteobacteria,1TIEA@1236|Gammaproteobacteria,1XYZ3@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_3772_13	55601.VANGNB10_cII0693	4.52e-63	213.0	COG1289@1|root,COG1289@2|Bacteria,1MWR1@1224|Proteobacteria,1RNIJ@1236|Gammaproteobacteria,1XTGG@135623|Vibrionales	135623|Vibrionales	S	membrane	yccS	-	-	-	-	-	-	-	-	-	-	-	FUSC-like,FUSC_2
k141_735_1	1265505.ATUG01000002_gene1556	5.45e-77	239.0	COG1319@1|root,COG1319@2|Bacteria,1RCRH@1224|Proteobacteria,42R7J@68525|delta/epsilon subdivisions,2WMT4@28221|Deltaproteobacteria,2MKWI@213118|Desulfobacterales	28221|Deltaproteobacteria	C	CO dehydrogenase flavoprotein C-terminal domain	-	-	1.17.1.4	ko:K13479	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103	RC00143	ko00000,ko00001,ko00002,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5
k141_1417_1	493475.GARC_4189	4.18e-28	119.0	COG3203@1|root,COG3203@2|Bacteria,1R91C@1224|Proteobacteria,1RTSN@1236|Gammaproteobacteria,467KV@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	Porin_4
k141_3773_1	203119.Cthe_3030	4.27e-09	64.7	COG0840@1|root,COG3852@1|root,COG0840@2|Bacteria,COG3852@2|Bacteria,1TP5A@1239|Firmicutes,247S3@186801|Clostridia,3WHE0@541000|Ruminococcaceae	186801|Clostridia	NT	methyl-accepting chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal
k141_96_1	1121396.KB893055_gene2634	1.61e-61	207.0	COG0840@1|root,COG0840@2|Bacteria,1R9DZ@1224|Proteobacteria,42YZJ@68525|delta/epsilon subdivisions	1224|Proteobacteria	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	-	-	-	-	-	-	-	-	-	CZB,MCPsignal
k141_4465_2	223926.28807500	8.95e-158	448.0	COG0008@1|root,COG0008@2|Bacteria,1MUN7@1224|Proteobacteria,1RMYQ@1236|Gammaproteobacteria,1XTZH@135623|Vibrionales	135623|Vibrionales	J	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon	gluQ	-	-	ko:K01894	-	-	-	-	ko00000,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1c
k141_4465_3	1219065.VPR01S_09_01360	2.87e-96	281.0	COG1734@1|root,COG1734@2|Bacteria,1RD08@1224|Proteobacteria,1S47H@1236|Gammaproteobacteria,1XTC3@135623|Vibrionales	135623|Vibrionales	T	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression	dksA	-	-	ko:K06204	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000,ko03009,ko03021	-	-	-	zf-dskA_traR
k141_4465_4	1191299.AJYX01000064_gene3501	0.000255	43.1	COG1489@1|root,COG1489@2|Bacteria,1MUC3@1224|Proteobacteria,1RQ95@1236|Gammaproteobacteria,1XTR1@135623|Vibrionales	135623|Vibrionales	S	Belongs to the SfsA family	sfsA	GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005975,GO:0008150,GO:0008152,GO:0044238,GO:0071704,GO:0097159,GO:1901363	-	ko:K06206	-	-	-	-	ko00000	-	-	-	SfsA
k141_3774_1	675814.VIC_004406	6.39e-98	300.0	COG1621@1|root,COG1621@2|Bacteria,1MWTX@1224|Proteobacteria,1RRZ2@1236|Gammaproteobacteria,1XUR7@135623|Vibrionales	135623|Vibrionales	G	COG1621 Beta-fructosidases (levanase invertase)	-	GO:0003674,GO:0003824,GO:0004553,GO:0004564,GO:0005975,GO:0005984,GO:0005985,GO:0005987,GO:0008150,GO:0008152,GO:0009056,GO:0009311,GO:0009313,GO:0009987,GO:0016052,GO:0016787,GO:0016798,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044275,GO:0046352,GO:0071704,GO:1901575	3.2.1.26	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00801,R00802,R02410,R03635,R03921,R06088	RC00028,RC00077	ko00000,ko00001,ko01000	-	GH32	-	Glyco_hydro_32C,Glyco_hydro_32N
k141_736_1	1217658.F987_03392	8.61e-120	372.0	2AEJW@1|root,314FG@2|Bacteria,1NBZ3@1224|Proteobacteria,1SQSR@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_3473_1	439235.Dalk_2357	6.06e-194	551.0	COG1271@1|root,COG1271@2|Bacteria,1MV60@1224|Proteobacteria,42MB8@68525|delta/epsilon subdivisions,2WIW7@28221|Deltaproteobacteria,2MID8@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM cytochrome bd ubiquinol oxidase subunit I	cydA	-	1.10.3.14	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	Cyt_bd_oxida_I
k141_5125_1	1205908.AKXW01000008_gene3227	5.57e-19	86.7	COG5421@1|root,COG5421@2|Bacteria,1R25F@1224|Proteobacteria,1RZQP@1236|Gammaproteobacteria,1XV94@135623|Vibrionales	135623|Vibrionales	L	Domain of unknown function (DUF4277)	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DUF4277
k141_5125_3	314292.VAS14_18299	7.01e-183	514.0	COG0667@1|root,COG0667@2|Bacteria,1MWGQ@1224|Proteobacteria,1RXDI@1236|Gammaproteobacteria,1Y0FA@135623|Vibrionales	135623|Vibrionales	C	Aldo/keto reductase family	-	-	1.1.1.122	ko:K00064	ko00051,ko00053,ko01100,ko01110,ko01120,map00051,map00053,map01100,map01110,map01120	M00114	R07675,R08926	RC00066,RC00161	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldo_ket_red
k141_5125_4	314292.VAS14_18294	6.61e-118	346.0	COG3618@1|root,COG3618@2|Bacteria,1MVG0@1224|Proteobacteria,1RNCH@1236|Gammaproteobacteria,1XZPF@135623|Vibrionales	135623|Vibrionales	S	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
k141_3474_1	317619.ANKN01000225_gene906	1.06e-67	230.0	COG0642@1|root,COG0745@1|root,COG3221@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria,COG3221@2|Bacteria,1GQYF@1117|Cyanobacteria	1117|Cyanobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
k141_4799_1	96561.Dole_2836	4.26e-246	696.0	COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,42M01@68525|delta/epsilon subdivisions,2WJ7M@28221|Deltaproteobacteria,2MHMW@213118|Desulfobacterales	28221|Deltaproteobacteria	V	Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation	msbA	-	-	ko:K06147,ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
k141_737_1	158190.SpiGrapes_0718	3.38e-131	380.0	COG1079@1|root,COG1079@2|Bacteria,2JA44@203691|Spirochaetes	203691|Spirochaetes	P	PFAM Branched-chain amino acid transport system permease component	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
k141_1418_1	96561.Dole_1977	2.71e-35	135.0	COG2204@1|root,COG2204@2|Bacteria,1QW1J@1224|Proteobacteria,43BRH@68525|delta/epsilon subdivisions,2X72C@28221|Deltaproteobacteria,2MPJ5@213118|Desulfobacterales	28221|Deltaproteobacteria	T	PFAM response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388,Response_reg
k141_738_1	1476973.JMMB01000007_gene318	1.65e-48	173.0	COG3290@1|root,COG3290@2|Bacteria,1TQJR@1239|Firmicutes,247YE@186801|Clostridia,25T52@186804|Peptostreptococcaceae	186801|Clostridia	T	Single cache domain 3	citS	-	2.7.13.3	ko:K11691	ko02020,map02020	M00489	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,PAS,PAS_8,PAS_9,SPOB_a,sCache_3_2
k141_3775_1	1304885.AUEY01000005_gene842	1.33e-163	472.0	COG1008@1|root,COG1008@2|Bacteria,1MV7V@1224|Proteobacteria,42NGD@68525|delta/epsilon subdivisions,2WJDC@28221|Deltaproteobacteria,2MJG3@213118|Desulfobacterales	28221|Deltaproteobacteria	C	TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M	nuoM	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q5_N,Proton_antipo_M
k141_3775_2	1304885.AUEY01000005_gene841	1.69e-108	332.0	COG0651@1|root,COG0651@2|Bacteria,1MV6V@1224|Proteobacteria,42MSA@68525|delta/epsilon subdivisions,2WIS1@28221|Deltaproteobacteria,2MHQ9@213118|Desulfobacterales	28221|Deltaproteobacteria	CP	plastoquinone (complex I)	-	-	-	ko:K05568,ko:K12137	-	-	-	-	ko00000,ko01000,ko02000	2.A.63.1,2.A.63.2	-	-	Proton_antipo_M
k141_5128_1	1304885.AUEY01000034_gene1890	9.81e-73	225.0	COG2121@1|root,COG2121@2|Bacteria,1MZID@1224|Proteobacteria,42UW6@68525|delta/epsilon subdivisions,2WQ4A@28221|Deltaproteobacteria,2MIV9@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF374)	-	-	-	ko:K09778	-	-	-	-	ko00000	-	-	-	DUF374
k141_5128_2	1286171.EAL2_808p00880	1.13e-24	105.0	COG1502@1|root,COG1502@2|Bacteria,1TQ2Q@1239|Firmicutes,24D0N@186801|Clostridia	186801|Clostridia	I	PLD-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PLDc_2
k141_5346_90	1511.CLOST_1478	8.13e-90	267.0	COG1396@1|root,COG1396@2|Bacteria,1V1K5@1239|Firmicutes,24FTC@186801|Clostridia,25R2E@186804|Peptostreptococcaceae	186801|Clostridia	K	AraC-like ligand binding domain	puuR	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,HTH_19,HTH_3
k141_5346_91	1121324.CLIT_23c04620	4.04e-62	197.0	COG1386@1|root,COG1386@2|Bacteria,1V6HI@1239|Firmicutes,24JW7@186801|Clostridia,25RCC@186804|Peptostreptococcaceae	186801|Clostridia	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves	scpB	-	-	ko:K06024	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpB
k141_5346_92	1391646.AVSU01000027_gene2413	8.95e-49	167.0	COG1354@1|root,COG1354@2|Bacteria,1TRW3@1239|Firmicutes,249VW@186801|Clostridia,25RMB@186804|Peptostreptococcaceae	186801|Clostridia	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves	scpA	-	-	ko:K05896	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpA
k141_5346_93	1511.CLOST_1481	7.55e-59	190.0	COG1994@1|root,COG1994@2|Bacteria,1V6D4@1239|Firmicutes,24K0D@186801|Clostridia,25RKB@186804|Peptostreptococcaceae	186801|Clostridia	S	Peptidase, M50 family	ywhC	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50
k141_5346_94	1286171.EAL2_c12580	2.26e-306	846.0	COG0595@1|root,COG0595@2|Bacteria,1TQ9G@1239|Firmicutes,2488J@186801|Clostridia,25V02@186806|Eubacteriaceae	186801|Clostridia	J	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay	rnj	-	-	ko:K12574	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	Lactamase_B,Lactamase_B_2,RMMBL
k141_5346_95	796940.HMPREF9628_01987	7.64e-60	189.0	COG0735@1|root,COG0735@2|Bacteria,1V7F0@1239|Firmicutes,24JQE@186801|Clostridia,25RK9@186804|Peptostreptococcaceae	186801|Clostridia	P	Ferric uptake regulator family	fur	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
k141_5346_97	1121324.CLIT_23c04570	2.76e-295	823.0	COG0370@1|root,COG0370@2|Bacteria,1TP7E@1239|Firmicutes,24885@186801|Clostridia	186801|Clostridia	P	transporter of a GTP-driven Fe(2 ) uptake system	feoB	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoB_C,FeoB_N,Gate
k141_5346_98	1121324.CLIT_23c04560	2.18e-28	103.0	COG1918@1|root,COG1918@2|Bacteria,1VEQU@1239|Firmicutes,24R31@186801|Clostridia	186801|Clostridia	P	PFAM FeoA family protein	-	-	-	ko:K04758	-	-	-	-	ko00000,ko02000	-	-	-	FeoA
k141_5346_99	350688.Clos_1662	7.79e-16	72.8	COG3906@1|root,COG3906@2|Bacteria,1VF5Z@1239|Firmicutes	1239|Firmicutes	S	Belongs to the UPF0473 family	-	-	-	-	-	-	-	-	-	-	-	-	DUF1292
k141_5346_100	445973.CLOBAR_02182	3.99e-58	184.0	COG0816@1|root,COG0816@2|Bacteria,1V6ER@1239|Firmicutes,24JGP@186801|Clostridia,25RGT@186804|Peptostreptococcaceae	186801|Clostridia	J	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA	yrrK	-	-	ko:K07447	-	-	-	-	ko00000,ko01000	-	-	-	RuvX
k141_5346_101	1511.CLOST_1488	1.24e-124	366.0	COG0667@1|root,COG1145@1|root,COG0667@2|Bacteria,COG1145@2|Bacteria,1UHXA@1239|Firmicutes,25E68@186801|Clostridia	186801|Clostridia	C	PFAM aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red,Fer4
k141_5346_102	1121324.CLIT_23c04530	3.5e-160	486.0	COG3119@1|root,COG3119@2|Bacteria,1TSMM@1239|Firmicutes,247YU@186801|Clostridia,25QS7@186804|Peptostreptococcaceae	186801|Clostridia	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_5346_103	478749.BRYFOR_07761	3.2e-29	106.0	COG4472@1|root,COG4472@2|Bacteria,1VAC4@1239|Firmicutes,24QVQ@186801|Clostridia	186801|Clostridia	S	Belongs to the UPF0297 family	yrzL	-	-	-	-	-	-	-	-	-	-	-	DUF965
k141_5346_104	1286171.EAL2_c12520	0.0	1102.0	COG0013@1|root,COG0013@2|Bacteria,1TPK6@1239|Firmicutes,248M3@186801|Clostridia,25V3M@186806|Eubacteriaceae	186801|Clostridia	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
k141_5346_105	1286171.EAL2_c12510	4.57e-171	487.0	COG0482@1|root,COG0482@2|Bacteria,1TPIZ@1239|Firmicutes,247YV@186801|Clostridia,25VKX@186806|Eubacteriaceae	186801|Clostridia	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
k141_5346_106	1151292.QEW_1657	1.45e-77	233.0	COG0822@1|root,COG0822@2|Bacteria,1V3H9@1239|Firmicutes,24HDD@186801|Clostridia,25RDC@186804|Peptostreptococcaceae	186801|Clostridia	C	NifU-like N terminal domain	nifU	-	-	ko:K04488	-	-	-	-	ko00000	-	-	-	NifU_N
k141_5346_107	1301100.HG529236_gene7241	7.92e-201	565.0	COG1104@1|root,COG1104@2|Bacteria,1TP21@1239|Firmicutes,24888@186801|Clostridia,36DXY@31979|Clostridiaceae	186801|Clostridia	E	Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
k141_5346_108	293826.Amet_2452	4.34e-56	179.0	COG1959@1|root,COG1959@2|Bacteria,1V3QB@1239|Firmicutes,24JIV@186801|Clostridia,36J5P@31979|Clostridiaceae	186801|Clostridia	K	Transcriptional regulator	iscR	-	-	-	-	-	-	-	-	-	-	-	Rrf2
k141_5346_109	1286171.EAL2_c12470	0.0	1667.0	COG1038@1|root,COG1038@2|Bacteria,1UHP9@1239|Firmicutes,25E5B@186801|Clostridia,25ZK1@186806|Eubacteriaceae	186801|Clostridia	C	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second	pyc	-	6.4.1.1	ko:K01958	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	M00173	R00344	RC00040,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS18410	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2,HMGL-like,PYC_OADA
k141_5346_110	37659.JNLN01000001_gene2612	2.68e-172	495.0	COG2256@1|root,COG2256@2|Bacteria,1TPVV@1239|Firmicutes,247X2@186801|Clostridia,36EXD@31979|Clostridiaceae	186801|Clostridia	L	AAA ATPase	yrvN	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA,AAA_assoc_2,MgsA_C,RuvB_N
k141_5346_111	1121324.CLIT_23c04440	5.73e-141	403.0	COG4465@1|root,COG4465@2|Bacteria,1TS7A@1239|Firmicutes,2480R@186801|Clostridia,25QEE@186804|Peptostreptococcaceae	186801|Clostridia	K	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor	codY	-	-	ko:K03706	-	-	-	-	ko00000,ko03000	-	-	-	CodY,HTH_CodY
k141_5346_113	1121324.CLIT_23c04430	0.0	948.0	COG0550@1|root,COG0550@2|Bacteria,1TPUS@1239|Firmicutes,248MG@186801|Clostridia,25R1U@186804|Peptostreptococcaceae	186801|Clostridia	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,zf-C4_Topoisom
k141_5346_114	1286171.EAL2_c12430	5.47e-98	303.0	COG0758@1|root,COG0758@2|Bacteria,1TPP7@1239|Firmicutes,24AS2@186801|Clostridia,25VKT@186806|Eubacteriaceae	186801|Clostridia	LU	DNA protecting protein DprA	dprA	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A
k141_5346_115	865861.AZSU01000003_gene2238	2.38e-95	286.0	COG0842@1|root,COG0842@2|Bacteria,1TSWD@1239|Firmicutes,24DHH@186801|Clostridia,36INU@31979|Clostridiaceae	186801|Clostridia	V	ABC-2 type transporter	yadH	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
k141_5346_116	927704.SELR_07230	3.22e-64	210.0	COG1131@1|root,COG1131@2|Bacteria,1TPMQ@1239|Firmicutes,4H28S@909932|Negativicutes	909932|Negativicutes	V	ABC transporter, ATP-binding protein	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
k141_5346_117	1321778.HMPREF1982_03472	2.83e-86	268.0	COG0614@1|root,COG0614@2|Bacteria,1UNE3@1239|Firmicutes,24AKE@186801|Clostridia	186801|Clostridia	P	PFAM periplasmic binding protein	-	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
k141_5346_118	1150621.SMUL_1551	1.99e-100	304.0	COG4822@1|root,COG4822@2|Bacteria,1P36Y@1224|Proteobacteria,42P9C@68525|delta/epsilon subdivisions	1224|Proteobacteria	H	Catalyzes the insertion of Co(2 ) into sirohydrochlorin	cbiK	GO:0003674,GO:0003824,GO:0004325,GO:0005488,GO:0005575,GO:0005623,GO:0008150,GO:0009987,GO:0016043,GO:0016829,GO:0016852,GO:0020037,GO:0022607,GO:0042597,GO:0043167,GO:0043169,GO:0043933,GO:0044085,GO:0044464,GO:0046872,GO:0046906,GO:0046914,GO:0048037,GO:0050897,GO:0051259,GO:0051262,GO:0051266,GO:0065003,GO:0071840,GO:0097159,GO:1901363	4.99.1.3	ko:K02190	ko00860,ko01100,map00860,map01100	-	R05807	RC01012	ko00000,ko00001,ko01000	-	-	-	CbiK
k141_5346_119	1444309.JAQG01000080_gene4024	5.54e-43	154.0	COG1120@1|root,COG1120@2|Bacteria,1TP2Q@1239|Firmicutes,4HETN@91061|Bacilli,26TUB@186822|Paenibacillaceae	91061|Bacilli	HP	ABC transporter	fecE	-	3.6.3.34	ko:K02013	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	ABC_tran
k141_5346_120	485916.Dtox_0557	1.78e-78	251.0	COG0609@1|root,COG0609@2|Bacteria,1TPX6@1239|Firmicutes,248IS@186801|Clostridia,260WJ@186807|Peptococcaceae	186801|Clostridia	U	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily	-	-	-	ko:K02015	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	FecCD
k141_3342_2	1238450.VIBNISOn1_1470021	2.45e-153	437.0	COG0007@1|root,COG0007@2|Bacteria,1MUI0@1224|Proteobacteria,1RM9V@1236|Gammaproteobacteria,1XSWE@135623|Vibrionales	135623|Vibrionales	H	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme	cysG	-	1.3.1.76,2.1.1.107,4.99.1.4	ko:K02302,ko:K02303	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03194,R03947	RC00003,RC00871,RC01012,RC01034	ko00000,ko00001,ko00002,ko01000	-	-	-	CysG_dimeriser,NAD_binding_7,Sirohm_synth_M,TP_methylase
k141_3342_3	1219076.N646_2477	3.35e-49	165.0	COG3061@1|root,COG3061@2|Bacteria,1R4XK@1224|Proteobacteria,1S430@1236|Gammaproteobacteria,1XXHC@135623|Vibrionales	135623|Vibrionales	M	COG3061 Cell envelope opacity-associated protein A	-	-	-	ko:K07269	-	-	-	-	ko00000	-	-	-	OapA,OapA_N
k141_3342_5	1517681.HW45_19180	1.11e-121	350.0	COG0545@1|root,COG0545@2|Bacteria,1RDA1@1224|Proteobacteria,1RPMP@1236|Gammaproteobacteria,1XTFI@135623|Vibrionales	135623|Vibrionales	O	COG0545 FKBP-type peptidyl-prolyl cis-trans isomerases 1	fklB	-	5.2.1.8	ko:K03773	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C,FKBP_N
k141_3342_6	675814.VIC_004885	4.09e-20	89.0	2C5EJ@1|root,331R8@2|Bacteria,1NDD9@1224|Proteobacteria,1SDIU@1236|Gammaproteobacteria,1XX02@135623|Vibrionales	135623|Vibrionales	S	Protein of unknown function VcgC/VcgE (DUF2780)	PP0330	-	-	-	-	-	-	-	-	-	-	-	DUF2780
k141_3342_7	1191299.AJYX01000052_gene1397	5.06e-267	735.0	COG2873@1|root,COG2873@2|Bacteria,1NQME@1224|Proteobacteria,1T1GA@1236|Gammaproteobacteria,1XUCM@135623|Vibrionales	135623|Vibrionales	E	COG2873 O-acetylhomoserine sulfhydrylase	metY	-	2.5.1.49	ko:K01740	ko00270,ko01100,map00270,map01100	-	R01287,R04859	RC00020,RC02821,RC02848	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
k141_3342_9	1187848.AJYQ01000109_gene499	1.19e-230	635.0	COG0202@1|root,COG0202@2|Bacteria,1MU75@1224|Proteobacteria,1RMU3@1236|Gammaproteobacteria,1XUZ5@135623|Vibrionales	135623|Vibrionales	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
k141_3342_10	945543.VIBR0546_15117	6.14e-137	388.0	COG0522@1|root,COG0522@2|Bacteria,1MW0U@1224|Proteobacteria,1RQ38@1236|Gammaproteobacteria,1XUJ0@135623|Vibrionales	135623|Vibrionales	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006417,GO:0006450,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019538,GO:0019843,GO:0022626,GO:0022627,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0071704,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
k141_3342_11	1280001.BAOA01000021_gene772	1.82e-87	257.0	COG0100@1|root,COG0100@2|Bacteria,1RD0A@1224|Proteobacteria,1S3Q2@1236|Gammaproteobacteria,1XWWG@135623|Vibrionales	135623|Vibrionales	J	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome	rpsK	GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
k141_3344_1	95619.PM1_0203315	2.32e-08	54.7	COG2823@1|root,COG2823@2|Bacteria	2|Bacteria	S	hyperosmotic response	osmY	-	-	ko:K04065	-	-	-	-	ko00000	-	-	-	BON
k141_3345_1	526222.Desal_0484	5.56e-50	163.0	COG4917@1|root,COG4917@2|Bacteria,1RIVR@1224|Proteobacteria,42WTZ@68525|delta/epsilon subdivisions,2WTCR@28221|Deltaproteobacteria,2MH75@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	Ethanolamine utilisation - propanediol utilisation	-	-	-	ko:K04029	-	-	-	-	ko00000	-	-	-	PduV-EutP
k141_3345_2	207559.Dde_3264	3.35e-58	182.0	COG4810@1|root,COG4810@2|Bacteria,1RFDA@1224|Proteobacteria,4307U@68525|delta/epsilon subdivisions,2WVEW@28221|Deltaproteobacteria,2MBZV@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	BMC domain	-	-	-	ko:K04031	-	-	-	-	ko00000	-	-	-	BMC
k141_3345_3	526222.Desal_0482	1.43e-14	70.1	COG4577@1|root,COG4577@2|Bacteria,1R55P@1224|Proteobacteria,42RUF@68525|delta/epsilon subdivisions,2WNT1@28221|Deltaproteobacteria,2MB2A@213115|Desulfovibrionales	28221|Deltaproteobacteria	CQ	BMC	-	-	-	-	-	-	-	-	-	-	-	-	BMC
k141_3346_1	28229.ND2E_2475	1.74e-56	180.0	COG1671@1|root,COG1671@2|Bacteria,1RCZA@1224|Proteobacteria,1S3QM@1236|Gammaproteobacteria,2Q6TA@267889|Colwelliaceae	1236|Gammaproteobacteria	S	Uncharacterized BCR, YaiI/YqxD family COG1671	yaiI	-	-	ko:K09768	-	-	-	-	ko00000	-	-	-	DUF188
k141_3346_2	555088.DealDRAFT_0417	2.68e-196	568.0	COG0318@1|root,COG0318@2|Bacteria,1TPSX@1239|Firmicutes,248JC@186801|Clostridia	186801|Clostridia	IQ	Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding
k141_3347_1	1121403.AUCV01000031_gene2844	2.21e-42	169.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42PUU@68525|delta/epsilon subdivisions,2WKGS@28221|Deltaproteobacteria,2MPUZ@213118|Desulfobacterales	28221|Deltaproteobacteria	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal,dCache_1
k141_3348_1	1713.JOFV01000009_gene360	1.09e-05	49.3	COG4319@1|root,COG4319@2|Bacteria,2HUJI@201174|Actinobacteria,4F2PT@85016|Cellulomonadaceae	201174|Actinobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
k141_3349_1	879212.DespoDRAFT_03179	1.65e-66	218.0	COG0589@1|root,COG0798@1|root,COG0589@2|Bacteria,COG0798@2|Bacteria,1R33W@1224|Proteobacteria,42P1K@68525|delta/epsilon subdivisions,2WKET@28221|Deltaproteobacteria,2MIXR@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Sodium Bile acid symporter family	-	-	-	-	-	-	-	-	-	-	-	-	SBF,Usp
k141_3349_2	767817.Desgi_2928	1.03e-22	94.7	COG2220@1|root,COG2220@2|Bacteria,1TSSV@1239|Firmicutes,24ETY@186801|Clostridia	186801|Clostridia	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2,Lactamase_B_3
k141_3352_1	326297.Sama_0675	1.64e-41	157.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,2QAY1@267890|Shewanellaceae	1236|Gammaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	czcA	-	-	ko:K18138	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
k141_3353_1	1304885.AUEY01000040_gene1606	4.71e-143	422.0	COG0402@1|root,COG0402@2|Bacteria,1MVPA@1224|Proteobacteria,42NI6@68525|delta/epsilon subdivisions,2WKI1@28221|Deltaproteobacteria,2MJDX@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine	mtaD	-	3.5.4.28,3.5.4.31	ko:K12960	ko00270,ko01100,map00270,map01100	-	R09660	RC00477	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
k141_3353_2	1121346.KB899830_gene682	5.53e-54	179.0	COG0005@1|root,COG0005@2|Bacteria,1TQ37@1239|Firmicutes,4HABP@91061|Bacilli,26TPG@186822|Paenibacillaceae	91061|Bacilli	F	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate	punA	-	2.4.2.1,2.4.2.28	ko:K00772,ko:K03783	ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110	M00034	R01402,R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244	RC00033,RC00063,RC00122,RC02819	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
k141_4392_1	500633.CLOHIR_01171	2.33e-154	489.0	COG1196@1|root,COG1196@2|Bacteria,1TPJV@1239|Firmicutes,249F4@186801|Clostridia,25QTR@186804|Peptostreptococcaceae	186801|Clostridia	D	Required for chromosome condensation and partitioning	smc	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
k141_4392_2	1121324.CLIT_23c04190	1.99e-132	389.0	COG1243@1|root,COG1243@2|Bacteria,1TS1F@1239|Firmicutes,248YV@186801|Clostridia,25QV2@186804|Peptostreptococcaceae	186801|Clostridia	BK	Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Fer4_14,Radical_SAM,Radical_SAM_C
k141_4392_3	1151292.QEW_1624	1.76e-96	288.0	COG0571@1|root,COG0571@2|Bacteria,1TPGC@1239|Firmicutes,249QD@186801|Clostridia,25QZ3@186804|Peptostreptococcaceae	186801|Clostridia	J	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism	rnc	-	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	-	-	-	Ribonucleas_3_3,dsrm
k141_4392_4	1280685.AUKC01000054_gene1426	2.35e-100	298.0	COG0745@1|root,COG0745@2|Bacteria,1TPRU@1239|Firmicutes,24843@186801|Clostridia,4BX95@830|Butyrivibrio	186801|Clostridia	T	Transcriptional regulatory protein, C terminal	srrA_2	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
k141_4392_5	1353529.M899_1199	9.82e-31	131.0	COG0642@1|root,COG2205@2|Bacteria,1MW8M@1224|Proteobacteria,42QF7@68525|delta/epsilon subdivisions,2WJAU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K07644	ko02020,map02020	M00452,M00745	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS_9,Response_reg
k141_3373_48	1391646.AVSU01000049_gene1648	1.05e-43	151.0	COG3758@1|root,COG3758@2|Bacteria,1VH52@1239|Firmicutes,24P8J@186801|Clostridia,25TMJ@186804|Peptostreptococcaceae	186801|Clostridia	S	HutD	-	-	-	-	-	-	-	-	-	-	-	-	HutD
k141_3373_49	1540257.JQMW01000009_gene2930	7.71e-94	285.0	COG2996@1|root,COG2996@2|Bacteria,1TQ1Z@1239|Firmicutes,2498C@186801|Clostridia,36EB0@31979|Clostridiaceae	186801|Clostridia	S	S1, RNA binding domain	cvfB	-	-	ko:K00243	-	-	-	-	ko00000	-	-	-	S1,S1_2
k141_3373_50	1121324.CLIT_10c03590	1.45e-60	196.0	COG2230@1|root,COG2230@2|Bacteria,1UMJ8@1239|Firmicutes,25H4D@186801|Clostridia	186801|Clostridia	M	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
k141_3373_52	1121324.CLIT_2c03880	5.35e-165	481.0	COG0351@1|root,COG0352@1|root,COG0351@2|Bacteria,COG0352@2|Bacteria,1TQ4A@1239|Firmicutes,2483H@186801|Clostridia	186801|Clostridia	H	Phosphomethylpyrimidine kinase	thiD	-	2.5.1.3,2.7.1.35,2.7.1.49,2.7.4.7	ko:K00868,ko:K00941,ko:K14153	ko00730,ko00750,ko01100,map00730,map00750,map01100	M00127	R00174,R01909,R02493,R03223,R03471,R04509,R10712	RC00002,RC00017,RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	Phos_pyr_kin
k141_3373_53	1211817.CCAT010000045_gene3043	0.0	909.0	COG0326@1|root,COG0326@2|Bacteria,1TQEU@1239|Firmicutes,247ND@186801|Clostridia,36DJ5@31979|Clostridiaceae	186801|Clostridia	O	Molecular chaperone. Has ATPase activity	htpG	-	-	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	-	-	-	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	-	-	-	HATPase_c,HATPase_c_3,HSP90
k141_3373_54	203119.Cthe_0035	2.18e-78	242.0	COG1145@1|root,COG1145@2|Bacteria,1TPAZ@1239|Firmicutes,249NJ@186801|Clostridia,3WGU7@541000|Ruminococcaceae	186801|Clostridia	C	4Fe-4S binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_6
k141_3373_56	1031288.AXAA01000034_gene2175	6.43e-65	213.0	COG2199@1|root,COG3706@2|Bacteria,1TQMM@1239|Firmicutes,24BS4@186801|Clostridia,36FXS@31979|Clostridiaceae	186801|Clostridia	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GGDEF,SpoOE-like
k141_3373_57	350688.Clos_1352	2.5e-76	233.0	COG2096@1|root,COG2096@2|Bacteria,1V3PI@1239|Firmicutes,24C7G@186801|Clostridia,36GUU@31979|Clostridiaceae	186801|Clostridia	S	adenosyltransferase	-	-	2.5.1.17	ko:K00798	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	Cob_adeno_trans,Haem_degrading
k141_3373_58	1347392.CCEZ01000021_gene841	9.78e-147	427.0	COG1108@1|root,COG1108@2|Bacteria,1TPZB@1239|Firmicutes,2487Y@186801|Clostridia,36GX3@31979|Clostridiaceae	186801|Clostridia	P	ABC 3 transport family	troD	-	-	ko:K09819,ko:K11709,ko:K19976	ko02010,map02010	M00243,M00319,M00792	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15,3.A.1.15.15	-	-	ABC-3,Fe_dep_repr_C,Fe_dep_repress
k141_3373_59	1347392.CCEZ01000021_gene842	5.62e-123	367.0	COG1108@1|root,COG1108@2|Bacteria,1TPZB@1239|Firmicutes,248FP@186801|Clostridia,36FPM@31979|Clostridiaceae	186801|Clostridia	P	ABC 3 transport family	-	-	-	ko:K09816,ko:K11708	ko02010,map02010	M00242,M00319	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15,3.A.1.15.3,3.A.1.15.5	-	-	ABC-3
k141_3373_60	1347392.CCEZ01000021_gene843	1.33e-132	380.0	COG1121@1|root,COG1121@2|Bacteria,1TQJ3@1239|Firmicutes,25B2N@186801|Clostridia,36DZK@31979|Clostridiaceae	186801|Clostridia	P	ATPases associated with a variety of cellular activities	mntA	-	3.6.3.35	ko:K09817,ko:K09820,ko:K11710,ko:K19973	ko02010,map02010	M00242,M00243,M00319,M00792	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.15,3.A.1.15.15,3.A.1.15.3,3.A.1.15.5	-	-	ABC_tran
k141_3373_61	1499689.CCNN01000009_gene2762	2.18e-109	327.0	COG0803@1|root,COG0803@2|Bacteria,1TRKU@1239|Firmicutes,247UW@186801|Clostridia,36VMT@31979|Clostridiaceae	186801|Clostridia	P	Belongs to the bacterial solute-binding protein 9 family	troA	-	-	ko:K11707	ko02010,map02010	M00319	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15	-	-	ZnuA
k141_3373_62	1511.CLOST_0666	1.26e-93	283.0	COG3752@1|root,COG3752@2|Bacteria,1V0FI@1239|Firmicutes,24GQX@186801|Clostridia	186801|Clostridia	S	3-oxo-5-alpha-steroid 4-dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	DUF1295
k141_3373_63	1293054.HSACCH_02152	7.09e-109	346.0	COG1307@1|root,COG1461@1|root,COG1307@2|Bacteria,COG1461@2|Bacteria,1TR6J@1239|Firmicutes,24A8H@186801|Clostridia,3WC9D@53433|Halanaerobiales	186801|Clostridia	S	Dak2	-	-	-	ko:K07030	-	-	-	-	ko00000	-	-	-	Dak2,DegV
k141_3373_64	1121289.JHVL01000005_gene990	6.09e-187	535.0	COG0534@1|root,COG0534@2|Bacteria,1TQ56@1239|Firmicutes,248YU@186801|Clostridia,36DVM@31979|Clostridiaceae	186801|Clostridia	V	MATE efflux family protein	-	-	-	-	-	-	-	-	-	-	-	-	MatE
k141_3373_65	1511.CLOST_0711	9.17e-48	161.0	COG1633@1|root,COG1633@2|Bacteria,1VAXV@1239|Firmicutes,24KX7@186801|Clostridia	186801|Clostridia	S	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2202
k141_3373_66	431943.CKL_3801	4.7e-101	300.0	COG0846@1|root,COG0846@2|Bacteria,1TQKD@1239|Firmicutes,2491J@186801|Clostridia,36DJK@31979|Clostridiaceae	186801|Clostridia	K	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form	cobB	-	-	ko:K12410	-	-	-	-	ko00000,ko01000	-	-	-	SIR2
k141_3373_67	293826.Amet_3384	1.6e-60	190.0	COG0229@1|root,COG0229@2|Bacteria,1UPN0@1239|Firmicutes,25HJF@186801|Clostridia,36IR9@31979|Clostridiaceae	186801|Clostridia	O	methionine sulfoxide reductase	msrB	-	1.8.4.11,1.8.4.12	ko:K07304,ko:K07305,ko:K12267	-	-	-	-	ko00000,ko01000	-	-	-	SelR
k141_3373_69	1237149.C900_03643	2.13e-85	265.0	COG0668@1|root,COG0668@2|Bacteria,4NFHD@976|Bacteroidetes,47PJS@768503|Cytophagia	976|Bacteroidetes	M	Mechanosensitive ion channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel
k141_3373_70	484019.THA_1039	3.34e-80	242.0	COG2109@1|root,COG2109@2|Bacteria,2GCV0@200918|Thermotogae	200918|Thermotogae	H	PFAM ATP corrinoid adenosyltransferase BtuR CobO CobP	-	-	2.5.1.17	ko:K19221	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	CobA_CobO_BtuR
k141_3373_72	1196322.A370_04229	1.4e-50	166.0	2ER8Z@1|root,33IUK@2|Bacteria,1VYKS@1239|Firmicutes,24T3C@186801|Clostridia,36RH9@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_3373_73	574375.BAGA_29345	2.4e-254	731.0	28IBY@1|root,2Z8EC@2|Bacteria,1TSCW@1239|Firmicutes,4HFBK@91061|Bacilli,1ZMDJ@1386|Bacillus	91061|Bacilli	S	Related to GH101 , GHL1-GHL3 family protein	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_129
k141_3373_74	742766.HMPREF9455_02349	1.14e-06	60.1	COG0745@1|root,COG3292@1|root,COG5002@1|root,COG0745@2|Bacteria,COG3292@2|Bacteria,COG5002@2|Bacteria,4P0IA@976|Bacteroidetes,2FWSR@200643|Bacteroidia,22WGG@171551|Porphyromonadaceae	976|Bacteroidetes	T	Y_Y_Y domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HTH_18,HisKA,Reg_prop,Response_reg,Y_Y_Y
k141_3373_75	189426.PODO_03935	5.97e-61	196.0	COG0745@1|root,COG0745@2|Bacteria,1V0F0@1239|Firmicutes,4HGH5@91061|Bacilli,26U77@186822|Paenibacillaceae	91061|Bacilli	T	regulator	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
k141_3373_76	1128398.Curi_c25490	4.87e-30	115.0	COG1618@1|root,COG1618@2|Bacteria,1VGU5@1239|Firmicutes,24QRA@186801|Clostridia,269XU@186813|unclassified Clostridiales	186801|Clostridia	F	NTPase	-	-	3.6.1.15	ko:K06928	ko00230,ko00730,ko01100,map00230,map00730,map01100	-	R00086,R00615	RC00002	ko00000,ko00001,ko01000	-	-	-	MobB,NTPase_1
k141_3373_77	1230342.CTM_24995	0.0	1152.0	COG1529@1|root,COG2080@1|root,COG1529@2|Bacteria,COG2080@2|Bacteria,1TP7U@1239|Firmicutes,248BV@186801|Clostridia,36DY8@31979|Clostridiaceae	186801|Clostridia	C	aldehyde oxidase and xanthine dehydrogenase, a b hammerhead	-	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2,Fer2,Fer2_2
k141_3373_78	748727.CLJU_c23790	2.19e-156	458.0	COG0044@1|root,COG0044@2|Bacteria,1TP8C@1239|Firmicutes,249W6@186801|Clostridia,36EQM@31979|Clostridiaceae	186801|Clostridia	F	PFAM amidohydrolase	hydA	-	3.5.2.2	ko:K01464	ko00240,ko00410,ko00770,ko00983,ko01100,map00240,map00410,map00770,map00983,map01100	M00046	R02269,R03055,R08227	RC00632,RC00680	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Amidohydro_1
k141_3373_79	1151292.QEW_3802	5.74e-175	498.0	COG0167@1|root,COG2768@1|root,COG0167@2|Bacteria,COG2768@2|Bacteria,1TRPI@1239|Firmicutes,24A0Z@186801|Clostridia	186801|Clostridia	C	Dihydroorotate dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	DHO_dh,Fer4
k141_3373_80	536232.CLM_3283	1.94e-215	608.0	COG2233@1|root,COG2233@2|Bacteria,1TNZZ@1239|Firmicutes,25CEM@186801|Clostridia,36DYC@31979|Clostridiaceae	186801|Clostridia	F	permease	-	-	-	ko:K03458	-	-	-	-	ko00000	2.A.40	-	-	Xan_ur_permease
k141_3373_81	1196322.A370_03992	9.81e-18	85.5	2FG4I@1|root,34811@2|Bacteria,1W01I@1239|Firmicutes,24NTK@186801|Clostridia,36SB8@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_3373_82	1347392.CCEZ01000043_gene105	4.39e-204	568.0	COG0078@1|root,COG0078@2|Bacteria,1TNY4@1239|Firmicutes,249P4@186801|Clostridia,36F9U@31979|Clostridiaceae	186801|Clostridia	E	Belongs to the ATCase OTCase family	-	-	-	-	-	-	-	-	-	-	-	-	OTCace,OTCace_N
k141_3373_83	318464.IO99_12205	1.99e-251	694.0	COG0624@1|root,COG0624@2|Bacteria,1TR99@1239|Firmicutes,248DC@186801|Clostridia,36G77@31979|Clostridiaceae	186801|Clostridia	E	peptidase	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
k141_3373_84	796940.HMPREF9628_01736	2.68e-205	577.0	COG1171@1|root,COG1171@2|Bacteria,1TR70@1239|Firmicutes,2485T@186801|Clostridia,25SHS@186804|Peptostreptococcaceae	186801|Clostridia	E	Pyridoxal-phosphate dependent enzyme	dpaL	-	4.3.1.15	ko:K01751	-	-	-	-	ko00000,ko01000	-	-	-	PALP
k141_4155_2	1232437.KL662015_gene1230	1.58e-12	67.4	COG0621@1|root,COG0621@2|Bacteria,1MURS@1224|Proteobacteria,42MQ3@68525|delta/epsilon subdivisions,2WJEE@28221|Deltaproteobacteria,2MHM5@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
k141_3839_1	713586.KB900536_gene2735	1.81e-10	64.7	COG3103@1|root,COG4991@2|Bacteria,1MX7M@1224|Proteobacteria,1RS74@1236|Gammaproteobacteria,1WY3A@135613|Chromatiales	135613|Chromatiales	T	SH3 domain	-	-	-	ko:K07184	-	-	-	-	ko00000	-	-	-	SH3_3
k141_3839_2	1268239.PALB_27980	1.92e-61	199.0	COG1720@1|root,COG1720@2|Bacteria,1MUF0@1224|Proteobacteria,1RPCX@1236|Gammaproteobacteria,2Q0DD@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	S	Uncharacterised protein family UPF0066	yaeB	GO:0000049,GO:0001510,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016426,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0089715,GO:0090304,GO:0097159,GO:0140098,GO:0140101,GO:1901360,GO:1901363	-	-	-	-	-	-	-	-	-	-	UPF0066
k141_3839_3	1415780.JPOG01000001_gene2866	3.6e-07	52.0	COG0443@1|root,COG0443@2|Bacteria,1P7BK@1224|Proteobacteria,1RRN2@1236|Gammaproteobacteria,1X4Q7@135614|Xanthomonadales	135614|Xanthomonadales	O	PRTRC system protein D	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_4156_1	1265505.ATUG01000003_gene462	5.78e-91	282.0	COG0111@1|root,COG0111@2|Bacteria,1MU5Z@1224|Proteobacteria,42M1C@68525|delta/epsilon subdivisions,2WIZQ@28221|Deltaproteobacteria,2MHQ6@213118|Desulfobacterales	28221|Deltaproteobacteria	E	D-isomer specific 2-hydroxyacid dehydrogenase catalytic	-	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C,ACT
k141_1806_1	595494.Tola_1706	1.48e-74	237.0	COG4542@1|root,COG4542@2|Bacteria,1NSRI@1224|Proteobacteria,1RPYP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	GHMP kinase	pduX	-	2.7.1.177	ko:K16651	ko00860,map00860	-	R06531	RC00002,RC00428	ko00000,ko00001,ko01000	-	-	-	GHMP_kinases_N
k141_1806_2	595494.Tola_1705	3.78e-126	373.0	COG0079@1|root,COG0079@2|Bacteria,1MW7I@1224|Proteobacteria,1RQQJ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	decarboxylates L-threonine-O-3-phosphate to yield (R)-1-amino-2-propanol O-2-phosphate, the precursor for the linkage between the nucleotide loop and the corrin ring in cobalamin	cobD	-	4.1.1.81	ko:K04720	ko00860,map00860	-	R06530	RC00517	ko00000,ko00001,ko01000	-	-	-	Aminotran_1_2
k141_1806_4	1348635.BBJY01000005_gene3147	6.53e-203	576.0	COG1797@1|root,COG1797@2|Bacteria,1MV7Z@1224|Proteobacteria,1RMCU@1236|Gammaproteobacteria,1XX2Q@135623|Vibrionales	135623|Vibrionales	H	Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source	cbiA	-	6.3.5.11,6.3.5.9	ko:K02224	ko00860,ko01100,ko01120,map00860,map01100,map01120	-	R05224,R05815	RC00010,RC01301	ko00000,ko00001,ko01000	-	-	-	CbiA,GATase_3
k141_1806_5	595494.Tola_1680	2.04e-141	409.0	COG1270@1|root,COG1270@2|Bacteria,1MURM@1224|Proteobacteria,1RN84@1236|Gammaproteobacteria	1236|Gammaproteobacteria	H	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group	cobD	-	6.3.1.10	ko:K02227	ko00860,ko01100,map00860,map01100	M00122	R06529,R07302	RC00090,RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	CobD_Cbib
k141_1806_6	595494.Tola_1679	1.1e-96	287.0	COG2082@1|root,COG2082@2|Bacteria,1MX1E@1224|Proteobacteria,1RYUX@1236|Gammaproteobacteria	1236|Gammaproteobacteria	H	Precorrin-8X methylmutase	cobH	-	5.4.99.60,5.4.99.61	ko:K06042	ko00860,ko01100,map00860,map01100	-	R05177,R05814	RC01292,RC01980	ko00000,ko00001,ko01000	-	-	-	CbiC
k141_1806_7	595494.Tola_1678	2.42e-190	538.0	COG1903@1|root,COG1903@2|Bacteria,1MXU3@1224|Proteobacteria,1S016@1236|Gammaproteobacteria	1236|Gammaproteobacteria	H	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A	cbiD	-	2.1.1.195	ko:K02188	ko00860,ko01100,map00860,map01100	-	R07773	RC00003,RC02051	ko00000,ko00001,ko01000	-	-	-	CbiD
k141_1130_1	118005.AWNK01000005_gene1474	1.19e-69	231.0	COG1301@1|root,COG1301@2|Bacteria	2|Bacteria	C	dicarboxylic acid transport	-	-	-	ko:K11102	-	-	-	-	ko00000,ko02000	2.A.23.1.1,2.A.23.1.2	-	-	SBP_bac_3,SDF
k141_1130_2	570268.ANBB01000061_gene945	4.95e-39	154.0	COG1944@1|root,COG1944@2|Bacteria,2I1IU@201174|Actinobacteria,4ENCC@85012|Streptosporangiales	201174|Actinobacteria	S	YcaO cyclodehydratase, ATP-ad Mg2+-binding	-	-	-	-	-	-	-	-	-	-	-	-	YcaO
k141_1808_1	177437.HRM2_14430	1.38e-51	168.0	COG1538@1|root,COG1538@2|Bacteria,1MYXE@1224|Proteobacteria,42TA7@68525|delta/epsilon subdivisions	1224|Proteobacteria	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC_sub_bind,OEP
k141_2123_1	223926.28805163	2.49e-187	529.0	COG0452@1|root,COG0452@2|Bacteria,1MVQP@1224|Proteobacteria,1RMKQ@1236|Gammaproteobacteria,1XT15@135623|Vibrionales	135623|Vibrionales	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	coaBC	-	4.1.1.36,6.3.2.5	ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
k141_2123_2	55601.VANGNB10_cI2548c	2e-125	360.0	COG2003@1|root,COG2003@2|Bacteria,1MXZ5@1224|Proteobacteria,1RP86@1236|Gammaproteobacteria,1XTU6@135623|Vibrionales	135623|Vibrionales	E	Belongs to the UPF0758 family	radC	GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360	-	ko:K03630	-	-	-	-	ko00000	-	-	-	RadC
k141_2123_3	1219065.VPR01S_04_02230	4.83e-48	153.0	COG0227@1|root,COG0227@2|Bacteria,1MZ57@1224|Proteobacteria,1S8UG@1236|Gammaproteobacteria,1XYCP@135623|Vibrionales	135623|Vibrionales	J	Belongs to the bacterial ribosomal protein bL28 family	rpmB	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02902	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L28
k141_2123_4	55601.VANGNB10_cI2546c	1.01e-30	108.0	COG0267@1|root,COG0267@2|Bacteria,1N6QV@1224|Proteobacteria,1SCEJ@1236|Gammaproteobacteria,1XYW1@135623|Vibrionales	135623|Vibrionales	J	Belongs to the bacterial ribosomal protein bL33 family	rpmG	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02913	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L33
k141_2123_5	1188252.AJYK01000038_gene1705	6.8e-49	156.0	COG2161@1|root,COG2161@2|Bacteria,1MZ7F@1224|Proteobacteria,1S8SD@1236|Gammaproteobacteria,1XXZ1@135623|Vibrionales	135623|Vibrionales	D	Antitoxin component of a toxin-antitoxin (TA) module	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
k141_2123_6	29495.EA26_14675	3.87e-55	173.0	COG3668@1|root,COG3668@2|Bacteria,1N0H5@1224|Proteobacteria,1S9FA@1236|Gammaproteobacteria,1XXSI@135623|Vibrionales	135623|Vibrionales	S	ParE toxin of type II toxin-antitoxin system, parDE	-	-	-	ko:K19092	-	-	-	-	ko00000,ko02048	-	-	-	ParE_toxin
k141_2123_7	575788.VS_0185	3.88e-52	171.0	2EG7K@1|root,339ZF@2|Bacteria,1NHRB@1224|Proteobacteria,1SIIJ@1236|Gammaproteobacteria,1XX2H@135623|Vibrionales	135623|Vibrionales	-	-	VV10822	-	-	-	-	-	-	-	-	-	-	-	-
k141_2123_8	1348635.BBJY01000016_gene4055	2.28e-128	370.0	COG0266@1|root,COG0266@2|Bacteria,1MVM5@1224|Proteobacteria,1RP3J@1236|Gammaproteobacteria,1XSAC@135623|Vibrionales	135623|Vibrionales	L	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates	fpg	GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
k141_502_1	543913.D521_0682	1.69e-14	81.3	COG2366@1|root,COG2366@2|Bacteria,1MVMH@1224|Proteobacteria,2VIWI@28216|Betaproteobacteria,1KQRW@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	S	Penicillin amidase	quiP	-	3.5.1.11	ko:K01434	ko00311,ko01130,map00311,map01130	-	R02170	RC00166,RC00328	ko00000,ko00001,ko01000,ko01002	-	-	-	Penicil_amidase
k141_502_2	521000.PROVRETT_09268	5.84e-39	139.0	COG3054@1|root,COG3054@2|Bacteria,1REC3@1224|Proteobacteria,1S3X5@1236|Gammaproteobacteria,3Z79G@586|Providencia	1236|Gammaproteobacteria	S	Bacterial protein of unknown function (YtfJ_HI0045)	ytfJ	-	-	ko:K07109	-	-	-	-	ko00000	-	-	-	YtfJ_HI0045
k141_502_3	1121423.JONT01000001_gene1880	2e-85	258.0	COG0352@1|root,COG0352@2|Bacteria,1V3ZR@1239|Firmicutes,24DG3@186801|Clostridia,26124@186807|Peptococcaceae	186801|Clostridia	H	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)	thiE	-	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	TMP-TENI
k141_5160_8	399739.Pmen_0117	1.84e-19	88.2	COG0834@1|root,COG0834@2|Bacteria,1RG0M@1224|Proteobacteria,1S4Z3@1236|Gammaproteobacteria	1236|Gammaproteobacteria	ET	Bacterial extracellular solute-binding proteins, family 3	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
k141_4561_1	1121405.dsmv_3305	6.68e-64	210.0	COG1253@1|root,COG1253@2|Bacteria,1MWT3@1224|Proteobacteria,42N45@68525|delta/epsilon subdivisions,2WKUD@28221|Deltaproteobacteria,2MHZA@213118|Desulfobacterales	28221|Deltaproteobacteria	S	CBS domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,DUF21
k141_770_1	177437.HRM2_21960	5.9e-109	353.0	COG1924@1|root,COG3580@1|root,COG3581@1|root,COG1924@2|Bacteria,COG3580@2|Bacteria,COG3581@2|Bacteria,1PKG6@1224|Proteobacteria,42MY4@68525|delta/epsilon subdivisions,2WJFI@28221|Deltaproteobacteria,2MIP0@213118|Desulfobacterales	28221|Deltaproteobacteria	I	BadF BadG BcrA BcrD	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG,DUF2229
k141_2142_1	1304885.AUEY01000055_gene199	6.66e-142	429.0	COG0761@1|root,COG0761@2|Bacteria,1MU7G@1224|Proteobacteria,42MJK@68525|delta/epsilon subdivisions,2WJ8V@28221|Deltaproteobacteria,2MI49@213118|Desulfobacterales	28221|Deltaproteobacteria	IM	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis	ispH	-	1.17.7.4	ko:K02945,ko:K03527	ko00900,ko01100,ko01110,ko01130,ko03010,map00900,map01100,map01110,map01130,map03010	M00096,M00178	R05884,R08210	RC01137,RC01487	br01610,ko00000,ko00001,ko00002,ko01000,ko03011	-	-	-	LYTB,UbiA
k141_523_2	675816.VIA_002890	6.59e-190	531.0	COG1897@1|root,COG1897@2|Bacteria,1MV64@1224|Proteobacteria,1RM7T@1236|Gammaproteobacteria,1XTIN@135623|Vibrionales	135623|Vibrionales	E	Transfers a succinyl group from succinyl-CoA to L- homoserine, forming succinyl-L-homoserine	metAS	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0008899,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0016748,GO:0016750,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.3.1.46	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	M00017	R01777	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	HTS
k141_523_3	1238450.VIBNISOn1_840066	8.05e-52	166.0	COG0645@1|root,COG0645@2|Bacteria,1N1S8@1224|Proteobacteria,1SEDC@1236|Gammaproteobacteria,1XXSN@135623|Vibrionales	135623|Vibrionales	S	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_33
k141_523_4	672.VV93_v1c14780	1.61e-23	91.7	2B5HC@1|root,31YC1@2|Bacteria,1QKAU@1224|Proteobacteria,1TIEB@1236|Gammaproteobacteria,1XYZ4@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_2784_1	1172562.HCN_1201	1.41e-49	174.0	COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,42MJD@68525|delta/epsilon subdivisions,2YRI0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Beta-eliminating lyase	-	-	2.6.1.102	ko:K13010	ko00520,map00520	-	R10460	RC00006,RC00781	ko00000,ko00001,ko01000,ko01005,ko01007	-	-	-	DegT_DnrJ_EryC1
k141_2784_2	13035.Dacsa_0259	1.84e-22	92.4	COG0500@1|root,COG2226@2|Bacteria,1GPYN@1117|Cyanobacteria	1117|Cyanobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
k141_3842_1	439235.Dalk_3722	1.92e-27	114.0	COG0457@1|root,COG0705@1|root,COG0457@2|Bacteria,COG0705@2|Bacteria,1MYFP@1224|Proteobacteria,42XRU@68525|delta/epsilon subdivisions,2WSW0@28221|Deltaproteobacteria,2MN73@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
k141_771_1	1121403.AUCV01000037_gene4262	7.59e-78	254.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42PUU@68525|delta/epsilon subdivisions,2WKGS@28221|Deltaproteobacteria,2MPUZ@213118|Desulfobacterales	28221|Deltaproteobacteria	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal,dCache_1
k141_1832_3	1121289.JHVL01000006_gene2903	4.14e-29	112.0	2CIIW@1|root,32UKR@2|Bacteria,1VBU0@1239|Firmicutes,24NQJ@186801|Clostridia,36MEF@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_524_1	55601.VANGNB10_cII0227	4.51e-98	291.0	COG4604@1|root,COG4604@2|Bacteria,1QU78@1224|Proteobacteria,1RP3Y@1236|Gammaproteobacteria,1XVHH@135623|Vibrionales	135623|Vibrionales	P	abc transporter atp-binding protein	vctC	-	3.6.3.34	ko:K02013	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	ABC_tran
k141_2785_1	880073.Calab_1800	4.02e-27	115.0	COG3852@1|root,COG4191@1|root,COG3852@2|Bacteria,COG4191@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
k141_773_1	1408428.JNJP01000003_gene3521	1.02e-22	99.8	29K99@1|root,3076K@2|Bacteria,1RJNR@1224|Proteobacteria,42SRE@68525|delta/epsilon subdivisions,2WPHQ@28221|Deltaproteobacteria,2MB6P@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Phage major capsid protein E	-	-	-	-	-	-	-	-	-	-	-	-	Phage_cap_E
k141_1833_1	1000565.METUNv1_00358	1.82e-64	209.0	COG3291@1|root,COG3291@2|Bacteria,1R08Z@1224|Proteobacteria	1224|Proteobacteria	S	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_2143_1	298386.PBPRB1352	1.44e-174	499.0	COG1301@1|root,COG1301@2|Bacteria,1R3SN@1224|Proteobacteria,1RN3B@1236|Gammaproteobacteria,1Y0IS@135623|Vibrionales	135623|Vibrionales	U	Sodium:dicarboxylate symporter family	-	-	-	-	-	-	-	-	-	-	-	-	SDF
k141_2786_1	1219065.VPR01S_10_00720	2.63e-173	510.0	COG2844@1|root,COG2844@2|Bacteria,1MV54@1224|Proteobacteria,1RN5T@1236|Gammaproteobacteria,1XU15@135623|Vibrionales	135623|Vibrionales	O	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen	glnD	GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006541,GO:0006542,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008773,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0070569,GO:0071704,GO:0140096,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.7.59	ko:K00990	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	-	-	-	ACT,GlnD_UR_UTase,HD,NTP_transf_2
k141_4563_2	1304885.AUEY01000006_gene730	4.19e-253	700.0	COG1158@1|root,COG1158@2|Bacteria,1MUCF@1224|Proteobacteria,42M15@68525|delta/epsilon subdivisions,2WIQN@28221|Deltaproteobacteria,2MI44@213118|Desulfobacterales	28221|Deltaproteobacteria	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
k141_4563_3	1226322.HMPREF1545_01798	9.46e-11	57.0	COG0254@1|root,COG0254@2|Bacteria,1VEGU@1239|Firmicutes,24QNZ@186801|Clostridia,2N7PC@216572|Oscillospiraceae	186801|Clostridia	J	Ribosomal protein L31	rpmE	-	-	ko:K02909	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31
k141_4169_1	1437425.CSEC_2062	1.8e-10	60.8	COG0300@1|root,COG0300@2|Bacteria,2JGY9@204428|Chlamydiae	204428|Chlamydiae	S	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
k141_4169_2	1219076.N646_0937	1.57e-86	258.0	COG1335@1|root,COG1335@2|Bacteria,1REQ3@1224|Proteobacteria,1SAXP@1236|Gammaproteobacteria,1XWGQ@135623|Vibrionales	135623|Vibrionales	Q	COG1335 Amidases related to nicotinamidase	-	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase
k141_4169_3	318161.Sden_2623	3.71e-60	191.0	COG1670@1|root,COG1670@2|Bacteria,1RC7M@1224|Proteobacteria,1S3B7@1236|Gammaproteobacteria,2QBQH@267890|Shewanellaceae	1236|Gammaproteobacteria	J	PFAM GCN5-related N-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
k141_4169_4	1515746.HR45_10890	7.49e-110	323.0	COG0639@1|root,COG0639@2|Bacteria,1N4BG@1224|Proteobacteria,1S3AZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Calcineurin-like phosphoesterase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos_2
k141_4169_5	870967.VIS19158_01869	6.88e-134	380.0	COG0009@1|root,COG0009@2|Bacteria,1MVPM@1224|Proteobacteria,1RNU8@1236|Gammaproteobacteria,1XTRN@135623|Vibrionales	135623|Vibrionales	J	Belongs to the SUA5 family	yciO	-	-	-	-	-	-	-	-	-	-	-	Sua5_yciO_yrdC
k141_4169_6	1238450.VIBNISOn1_970187	2.66e-141	407.0	COG0613@1|root,COG0613@2|Bacteria,1MWIH@1224|Proteobacteria,1RNCG@1236|Gammaproteobacteria,1XSAZ@135623|Vibrionales	135623|Vibrionales	S	metal-dependent phosphoesterases (PHP family)	trpH	-	3.1.3.97	ko:K07053	-	-	R00188,R11188	RC00078	ko00000,ko01000	-	-	-	PHP
k141_4169_7	55601.VANGNB10_cI1025c	1e-269	751.0	COG0147@1|root,COG0147@2|Bacteria,1MVBJ@1224|Proteobacteria,1RMSE@1236|Gammaproteobacteria,1XSGC@135623|Vibrionales	135623|Vibrionales	E	COG0147 Anthranilate para-aminobenzoate synthases component I	trpE	GO:0000162,GO:0003674,GO:0003824,GO:0004049,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005950,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016833,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494	4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
k141_4169_8	1188252.AJYK01000104_gene27	5.14e-109	317.0	COG0512@1|root,COG0512@2|Bacteria,1RAKJ@1224|Proteobacteria,1RREB@1236|Gammaproteobacteria,1XTCZ@135623|Vibrionales	135623|Vibrionales	EH	COG0512 Anthranilate para-aminobenzoate synthases component II	trpG	GO:0000162,GO:0003674,GO:0003824,GO:0004049,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005950,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016833,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494	4.1.3.27	ko:K01658	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
k141_4169_9	243277.VC_1172	1.06e-150	431.0	COG0547@1|root,COG0547@2|Bacteria,1MUPV@1224|Proteobacteria,1RNXV@1236|Gammaproteobacteria,1XT64@135623|Vibrionales	135623|Vibrionales	F	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)	trpD	GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.4.2.18	ko:K00766	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R01073	RC00440	ko00000,ko00001,ko00002,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3
k141_2787_1	1173020.Cha6605_2697	1.62e-84	281.0	COG0145@1|root,COG0146@1|root,COG0145@2|Bacteria,COG0146@2|Bacteria,1G02W@1117|Cyanobacteria	1117|Cyanobacteria	EQ	N-methylhydantoinase B acetone carboxylase alpha subunit	oplaH	-	3.5.2.9	ko:K01469	ko00480,map00480	-	R00251	RC00553	ko00000,ko00001,ko01000	-	-	-	Hydant_A_N,Hydantoinase_A,Hydantoinase_B
k141_2144_2	1304885.AUEY01000012_gene1792	2.12e-81	261.0	COG0446@1|root,COG1902@1|root,COG0446@2|Bacteria,COG1902@2|Bacteria,1MVE0@1224|Proteobacteria,42PDA@68525|delta/epsilon subdivisions,2WK05@28221|Deltaproteobacteria,2MHS3@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM NADH flavin oxidoreductase NADH oxidase	-	-	1.3.1.34	ko:K00219	-	-	-	-	ko00000,ko01000	-	-	-	Oxidored_FMN,Pyr_redox_2
k141_2145_1	1506583.JQJY01000009_gene1128	5.77e-45	162.0	COG0389@1|root,COG0389@2|Bacteria,4NGPH@976|Bacteroidetes,1HX7U@117743|Flavobacteriia,2NTED@237|Flavobacterium	976|Bacteroidetes	L	SOS mutagenesis and repair protein UmuC	umuC	-	-	ko:K03502	-	-	-	-	ko00000,ko03400	-	-	-	DUF4113,IMS,IMS_C,IMS_HHH
k141_1835_1	113355.CM001775_gene1582	3.26e-43	174.0	COG2202@1|root,COG3920@1|root,COG2202@2|Bacteria,COG3920@2|Bacteria,1GHCI@1117|Cyanobacteria	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	CBS,GAF,HATPase_c,HisKA_2,PAS,PAS_3,PAS_4,PAS_8,PAS_9
k141_525_1	1304885.AUEY01000032_gene2015	4.73e-113	331.0	COG1469@1|root,COG1469@2|Bacteria,1MV1B@1224|Proteobacteria,42N4U@68525|delta/epsilon subdivisions,2WJR7@28221|Deltaproteobacteria,2MHSN@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Converts GTP to 7,8-dihydroneopterin triphosphate	folE2	-	3.5.4.16	ko:K09007	ko00790,ko01100,map00790,map01100	M00126	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	GCHY-1
k141_525_2	1121459.AQXE01000003_gene1053	1.36e-58	193.0	COG0037@1|root,COG0037@2|Bacteria,1MW5Q@1224|Proteobacteria,42MMC@68525|delta/epsilon subdivisions,2WN12@28221|Deltaproteobacteria,2M7XC@213115|Desulfovibrionales	28221|Deltaproteobacteria	D	PP-loop domain protein	ttcA	-	-	ko:K14058	-	-	-	-	ko00000,ko03016	-	-	-	ATP_bind_3
k141_525_3	1304885.AUEY01000032_gene2013	2.54e-25	95.5	COG1758@1|root,COG1758@2|Bacteria,1N6TX@1224|Proteobacteria,42V07@68525|delta/epsilon subdivisions,2WRQ6@28221|Deltaproteobacteria,2MKV2@213118|Desulfobacterales	28221|Deltaproteobacteria	K	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits	rpoZ	-	2.7.7.6	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb6
k141_525_4	96561.Dole_2221	1.45e-71	219.0	COG0782@1|root,COG0782@2|Bacteria,1RCXW@1224|Proteobacteria,42SDX@68525|delta/epsilon subdivisions,2WP41@28221|Deltaproteobacteria,2MK62@213118|Desulfobacterales	28221|Deltaproteobacteria	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	-	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
k141_525_5	56780.SYN_00911	2.4e-115	340.0	COG0136@1|root,COG0136@2|Bacteria,1MUHG@1224|Proteobacteria,42MDM@68525|delta/epsilon subdivisions,2WJ5Y@28221|Deltaproteobacteria,2MQ48@213462|Syntrophobacterales	28221|Deltaproteobacteria	E	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate	asd	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
k141_1836_1	1517681.HW45_24980	3.75e-78	241.0	COG1940@1|root,COG1940@2|Bacteria,1MU94@1224|Proteobacteria,1RNHE@1236|Gammaproteobacteria,1XSU2@135623|Vibrionales	135623|Vibrionales	F	Catalyzes the phosphorylation of N-acetyl-D-glucosamine (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P	nagK	-	2.7.1.59	ko:K00884	ko00520,ko01100,map00520,map01100	-	R01201	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	ROK
k141_1836_2	675813.VIB_001267	1.1e-28	104.0	2CBU7@1|root,32ZCT@2|Bacteria,1N85K@1224|Proteobacteria,1SCKM@1236|Gammaproteobacteria,1XYDW@135623|Vibrionales	135623|Vibrionales	S	Protein of unknown function (DUF2960)	SO1372	-	-	-	-	-	-	-	-	-	-	-	DUF2960
k141_776_1	55601.VANGNB10_cI1728c	8.28e-123	363.0	COG0156@1|root,COG0156@2|Bacteria,1MVVH@1224|Proteobacteria,1RNS6@1236|Gammaproteobacteria,1XTHY@135623|Vibrionales	135623|Vibrionales	H	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide	bioF	GO:0003674,GO:0003824,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008710,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0017144,GO:0018130,GO:0019752,GO:0032787,GO:0034641,GO:0042364,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.3.1.47	ko:K00652	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03210,R10124	RC00004,RC00039,RC02725	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
k141_776_2	1051646.VITU9109_16353	1.53e-227	629.0	COG0502@1|root,COG0502@2|Bacteria,1MVFF@1224|Proteobacteria,1RMEQ@1236|Gammaproteobacteria,1XTAY@135623|Vibrionales	135623|Vibrionales	H	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism	bioB	GO:0003674,GO:0003824,GO:0004076,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0017144,GO:0018130,GO:0019752,GO:0032787,GO:0034641,GO:0042364,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.8.1.6	ko:K01012	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R01078	RC00441	ko00000,ko00001,ko00002,ko01000	-	-	-	BATS,Radical_SAM
k141_1837_2	1123274.KB899424_gene2985	5.93e-26	101.0	2D02B@1|root,32T7K@2|Bacteria,2J8CX@203691|Spirochaetes	203691|Spirochaetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_777_2	177437.HRM2_26780	9.33e-48	154.0	COG0776@1|root,COG0776@2|Bacteria,1MZ7M@1224|Proteobacteria,42TVD@68525|delta/epsilon subdivisions,2WQPX@28221|Deltaproteobacteria,2MKA9@213118|Desulfobacterales	28221|Deltaproteobacteria	L	Belongs to the bacterial histone-like protein family	ihfB	-	-	ko:K05788	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
k141_777_3	1121405.dsmv_3230	5.01e-15	73.2	COG0250@1|root,COG0250@2|Bacteria,1QTE5@1224|Proteobacteria,42QT0@68525|delta/epsilon subdivisions,2WN4B@28221|Deltaproteobacteria,2MJNB@213118|Desulfobacterales	28221|Deltaproteobacteria	K	Transcription termination factor nusG	-	-	-	ko:K05785	-	-	-	-	ko00000,ko03000	-	-	-	NusG
k141_3168_1	675806.VII_001948	0.0	1209.0	COG1674@1|root,COG1674@2|Bacteria,1MVPI@1224|Proteobacteria,1RM9A@1236|Gammaproteobacteria,1XUE7@135623|Vibrionales	135623|Vibrionales	D	COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins	ftsK	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
k141_3168_2	55601.VANGNB10_cI0997	4.08e-110	317.0	COG1522@1|root,COG1522@2|Bacteria,1MX7R@1224|Proteobacteria,1RPGA@1236|Gammaproteobacteria,1XVIW@135623|Vibrionales	135623|Vibrionales	K	COG1522 Transcriptional regulators	lrp	-	-	ko:K03719	-	-	-	-	ko00000,ko03000,ko03036	-	-	-	AsnC_trans_reg,HTH_24
k141_3168_3	29495.EA26_15955	5.22e-125	363.0	COG0583@1|root,COG0583@2|Bacteria,1MU8N@1224|Proteobacteria,1RN7T@1236|Gammaproteobacteria,1XTGJ@135623|Vibrionales	135623|Vibrionales	K	Transcriptional regulator	cysB	-	-	ko:K13634	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,LysR_substrate
k141_527_1	1348635.BBJY01000010_gene1335	1.17e-94	287.0	28IJT@1|root,2Z8KN@2|Bacteria,1R6VB@1224|Proteobacteria,1RNYB@1236|Gammaproteobacteria	1236|Gammaproteobacteria	H	PFAM Dinitrogenase reductase ADP-ribosyltransferase	draT	-	2.4.2.37	ko:K05951	-	-	-	-	ko00000,ko01000	-	-	-	DRAT
k141_527_2	1515746.HR45_02005	6.24e-82	253.0	COG1397@1|root,COG1397@2|Bacteria,1NTUR@1224|Proteobacteria,1RMPE@1236|Gammaproteobacteria,2QDVT@267890|Shewanellaceae	1236|Gammaproteobacteria	O	ADP-ribosylglycohydrolase	draG	-	3.2.2.24	ko:K05521	-	-	-	-	ko00000,ko01000	-	-	-	ADP_ribosyl_GH
k141_1464_2	1348635.BBJY01000010_gene1323	2.96e-112	329.0	COG2186@1|root,COG2186@2|Bacteria,1MY1K@1224|Proteobacteria,1RMUE@1236|Gammaproteobacteria,1XVWP@135623|Vibrionales	135623|Vibrionales	K	COG2186 Transcriptional regulators	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
k141_1464_4	382245.ASA_2140	6.24e-170	481.0	COG1879@1|root,COG1879@2|Bacteria,1MXJS@1224|Proteobacteria,1RRZV@1236|Gammaproteobacteria,1Y481@135624|Aeromonadales	135624|Aeromonadales	G	Periplasmic binding protein domain	-	-	-	ko:K02058	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	Peripla_BP_4
k141_1464_5	1348635.BBJY01000016_gene3965	1.74e-263	733.0	COG1129@1|root,COG1129@2|Bacteria,1MU22@1224|Proteobacteria,1RMCH@1236|Gammaproteobacteria,1XY8T@135623|Vibrionales	135623|Vibrionales	G	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	3.6.3.17	ko:K02056	-	M00221	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.2	-	-	ABC_tran
k141_1464_6	1348635.BBJY01000016_gene3964	3.23e-161	461.0	COG1172@1|root,COG1172@2|Bacteria,1MX7D@1224|Proteobacteria,1RNTS@1236|Gammaproteobacteria,1XTC8@135623|Vibrionales	135623|Vibrionales	G	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
k141_1464_7	1348635.BBJY01000016_gene3963	8.31e-167	474.0	COG1172@1|root,COG1172@2|Bacteria,1MX7D@1224|Proteobacteria,1RNTS@1236|Gammaproteobacteria,1XTC8@135623|Vibrionales	135623|Vibrionales	G	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
k141_1464_8	553178.CAPGI0001_0758	5.09e-32	130.0	COG0778@1|root,COG0778@2|Bacteria,4NQ04@976|Bacteroidetes,1IAV3@117743|Flavobacteriia,1ER52@1016|Capnocytophaga	976|Bacteroidetes	C	Nitroreductase	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
k141_1464_9	55601.VANGNB10_cI2661c	1.03e-180	505.0	COG0662@1|root,COG2207@1|root,COG0662@2|Bacteria,COG2207@2|Bacteria,1QUC1@1224|Proteobacteria,1T1SJ@1236|Gammaproteobacteria,1Y344@135623|Vibrionales	135623|Vibrionales	K	helix_turn_helix, arabinose operon control protein	-	-	-	ko:K02099	-	-	-	-	ko00000,ko03000	-	-	-	-
k141_1464_10	55601.VANGNB10_cI2662c	5.78e-51	168.0	2AW95@1|root,31N4G@2|Bacteria,1QJVY@1224|Proteobacteria,1THXK@1236|Gammaproteobacteria,1XXUB@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_1464_11	223926.28810078	1.95e-275	763.0	COG2160@1|root,COG2160@2|Bacteria,1MW0J@1224|Proteobacteria,1RQEF@1236|Gammaproteobacteria,1XSFJ@135623|Vibrionales	135623|Vibrionales	G	Catalyzes the conversion of L-arabinose to L-ribulose	araA	-	5.3.1.4	ko:K01804	ko00040,ko01100,map00040,map01100	-	R01761	RC00516	ko00000,ko00001,ko01000	-	-	-	Arabinose_Iso_C,Arabinose_Isome
k141_1464_13	223926.28810074	3.01e-287	793.0	COG1129@1|root,COG1129@2|Bacteria,1MU22@1224|Proteobacteria,1RSMB@1236|Gammaproteobacteria,1XVYA@135623|Vibrionales	135623|Vibrionales	G	Part of the ABC transporter complex AraFGH involved in arabinose import. Responsible for energy coupling to the transport system	araG	-	3.6.3.17	ko:K10441,ko:K10539	ko02010,map02010	M00212,M00213	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19,3.A.1.2.2	-	-	ABC_tran
k141_1464_15	525898.Sdel_1227	2.26e-37	157.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,43AT9@68525|delta/epsilon subdivisions,2YT2Z@29547|Epsilonproteobacteria	1224|Proteobacteria	T	GGDEF domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,EAL,GGDEF,MASE1,MHYT,PAS_8,dCache_1
k141_1464_16	722419.PH505_al00860	2.76e-105	313.0	COG3384@1|root,COG3384@2|Bacteria,1MXJZ@1224|Proteobacteria,1RR5P@1236|Gammaproteobacteria,2PZZI@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	S	Catalytic LigB subunit of aromatic ring-opening dioxygenase	-	-	-	ko:K15777	ko00965,map00965	-	R08836	RC00387	ko00000,ko00001,ko01000	-	-	-	LigB
k141_1553_30	1033737.CAEV01000043_gene1457	1.87e-96	292.0	COG0284@1|root,COG0284@2|Bacteria,1TQ7P@1239|Firmicutes,247SZ@186801|Clostridia,36E3E@31979|Clostridiaceae	186801|Clostridia	F	Belongs to the OMP decarboxylase family. Type 2 subfamily	pyrF	-	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS17585	OMPdecase
k141_1553_31	1123009.AUID01000034_gene1215	6.63e-107	327.0	COG0044@1|root,COG0044@2|Bacteria,1TPQM@1239|Firmicutes,247V2@186801|Clostridia,267UG@186813|unclassified Clostridiales	186801|Clostridia	F	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily	pyrC	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
k141_1553_32	536232.CLM_3652	1.21e-48	160.0	COG1781@1|root,COG1781@2|Bacteria,1V6U9@1239|Firmicutes,24JJU@186801|Clostridia,36JII@31979|Clostridiaceae	186801|Clostridia	F	aspartate carbamoyltransferase, regulatory	pyrI	-	-	ko:K00610	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002	-	-	-	PyrI,PyrI_C
k141_1553_33	857293.CAAU_1392	2.74e-156	446.0	COG0540@1|root,COG0540@2|Bacteria,1TQ96@1239|Firmicutes,2496D@186801|Clostridia,36DT0@31979|Clostridiaceae	186801|Clostridia	F	Belongs to the ATCase OTCase family	pyrB	-	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N,PyrI_C
k141_1553_35	1304284.L21TH_1824	1.39e-283	779.0	COG0334@1|root,COG0334@2|Bacteria,1TP45@1239|Firmicutes,24960@186801|Clostridia,36EGU@31979|Clostridiaceae	186801|Clostridia	E	Belongs to the Glu Leu Phe Val dehydrogenases family	gdh	GO:0003674,GO:0003824,GO:0004352,GO:0004353,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0055114,GO:0071704,GO:1901564	1.4.1.3,1.4.1.4	ko:K00261,ko:K00262	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
k141_1553_36	1121324.CLIT_20c00210	2.64e-76	240.0	COG1302@1|root,COG1302@2|Bacteria,1V1TU@1239|Firmicutes,24E60@186801|Clostridia	186801|Clostridia	F	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Asp23,IPT
k141_1553_37	1304284.L21TH_0868	2.32e-14	67.0	COG2768@1|root,COG2768@2|Bacteria,1VET2@1239|Firmicutes,24QUH@186801|Clostridia,36MIM@31979|Clostridiaceae	186801|Clostridia	C	Ferredoxin	fdxA	GO:0003674,GO:0003824,GO:0005488,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016491,GO:0022900,GO:0044237,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114	-	-	-	-	-	-	-	-	-	-	Fer4
k141_1553_38	1121324.CLIT_20c00190	1.86e-108	318.0	COG2344@1|root,COG2344@2|Bacteria,1TSMR@1239|Firmicutes,247RQ@186801|Clostridia,25R18@186804|Peptostreptococcaceae	186801|Clostridia	K	Modulates transcription in response to changes in cellular NADH NAD( ) redox state	rex	-	-	ko:K01926	-	-	-	-	ko00000,ko03000	-	-	-	CoA_binding,Put_DNA-bind_N
k141_1553_39	1151292.QEW_0191	1.28e-241	689.0	COG0488@1|root,COG0488@2|Bacteria,1TPAX@1239|Firmicutes,247U6@186801|Clostridia,25R5G@186804|Peptostreptococcaceae	186801|Clostridia	S	ABC transporter, ATP-binding protein	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
k141_1553_40	1301100.HG529422_gene4234	6.98e-179	505.0	COG0533@1|root,COG0533@2|Bacteria,1TQDR@1239|Firmicutes,247MG@186801|Clostridia,36DHM@31979|Clostridiaceae	186801|Clostridia	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	-	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
k141_1553_41	1280689.AUJC01000001_gene2348	5.63e-41	140.0	COG0454@1|root,COG0456@2|Bacteria,1V6KU@1239|Firmicutes,24J9Z@186801|Clostridia,36JIM@31979|Clostridiaceae	186801|Clostridia	K	This enzyme acetylates the N-terminal alanine of ribosomal protein S18	rimI	-	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1,Acetyltransf_10
k141_1553_42	500633.CLOHIR_00037	1.63e-62	202.0	COG1214@1|root,COG1214@2|Bacteria,1V4YX@1239|Firmicutes,24A0P@186801|Clostridia,25QHX@186804|Peptostreptococcaceae	186801|Clostridia	O	Universal bacterial protein YeaZ	yeaZ	-	-	ko:K14742	-	-	-	-	ko00000,ko03016	-	-	-	Acetyltransf_1,Peptidase_M22
k141_1553_43	272563.CD630_01490	9.28e-67	206.0	COG0802@1|root,COG0802@2|Bacteria,1V6CV@1239|Firmicutes,24MSS@186801|Clostridia,25RB4@186804|Peptostreptococcaceae	186801|Clostridia	S	Threonylcarbamoyl adenosine biosynthesis protein TsaE	ydiB	-	-	ko:K06925	-	-	-	-	ko00000,ko03016	-	-	-	TsaE
k141_1553_44	1121324.CLIT_20c00130	2.62e-73	227.0	COG3601@1|root,COG3601@2|Bacteria,1V4BW@1239|Firmicutes,24E4V@186801|Clostridia,25T8Q@186804|Peptostreptococcaceae	186801|Clostridia	U	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins	ribU	-	-	-	-	-	-	-	-	-	-	-	ECF_trnsprt
k141_1553_45	1304284.L21TH_1551	1.87e-180	513.0	COG1228@1|root,COG1228@2|Bacteria,1TPNQ@1239|Firmicutes,248UT@186801|Clostridia,36E56@31979|Clostridiaceae	186801|Clostridia	Q	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,Amidohydro_3
k141_1553_46	1151292.QEW_0169	1.07e-300	845.0	COG2183@1|root,COG2183@2|Bacteria,1TPFE@1239|Firmicutes,248P0@186801|Clostridia,25QRG@186804|Peptostreptococcaceae	186801|Clostridia	K	Tex-like protein	yhgF	-	-	ko:K06959	-	-	-	-	ko00000	-	-	-	HHH_3,S1,Tex_N,Tex_YqgF
k141_1553_47	293826.Amet_0796	1.43e-09	60.1	COG1516@1|root,COG1516@2|Bacteria,1VGUR@1239|Firmicutes,24QV2@186801|Clostridia,36MM8@31979|Clostridiaceae	186801|Clostridia	N	Flagellar protein FliS	-	-	-	ko:K02422	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliS
k141_1553_48	1121324.CLIT_20c00090	3.17e-226	642.0	COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia	186801|Clostridia	N	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella	hag	-	-	ko:K02406	ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flagellin_C,Flagellin_N
k141_1553_49	1410630.JNKP01000004_gene475	4.71e-09	59.7	COG1516@1|root,COG1516@2|Bacteria,1VD1Q@1239|Firmicutes,24PMH@186801|Clostridia,27P09@186928|unclassified Lachnospiraceae	186801|Clostridia	NOU	Flagellar protein FliS	-	-	-	ko:K02422	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliS
k141_1553_50	1121324.CLIT_20c00090	2.66e-215	615.0	COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia	186801|Clostridia	N	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella	hag	-	-	ko:K02406	ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flagellin_C,Flagellin_N
k141_1553_51	350688.Clos_2480	1.55e-21	87.8	COG2257@1|root,COG2257@2|Bacteria,1VF4R@1239|Firmicutes,24QSW@186801|Clostridia,36NNP@31979|Clostridiaceae	186801|Clostridia	N	cytoplasmic domain of flagellar protein FhlB	flhB1	-	-	ko:K04061	-	-	-	-	ko00000,ko02044	-	-	-	Bac_export_2
k141_1553_52	1511.CLOST_2308	6.6e-43	178.0	COG1196@1|root,COG1196@2|Bacteria,1V4Z9@1239|Firmicutes,24I4M@186801|Clostridia,25SCR@186804|Peptostreptococcaceae	186801|Clostridia	D	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_1553_53	1286171.EAL2_c17730	4.94e-48	159.0	COG1728@1|root,COG1728@2|Bacteria,1VF6M@1239|Firmicutes,24S6C@186801|Clostridia,25WM8@186806|Eubacteriaceae	186801|Clostridia	S	Protein of unknown function (DUF327)	-	-	-	ko:K09770	-	-	-	-	ko00000	-	-	-	DUF327
k141_1553_54	1391646.AVSU01000017_gene3113	4.99e-156	448.0	COG1186@1|root,COG1186@2|Bacteria,1TPSB@1239|Firmicutes,247KU@186801|Clostridia,25QGI@186804|Peptostreptococcaceae	186801|Clostridia	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	-	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
k141_1553_55	1286171.EAL2_c17750	0.0	1241.0	COG0653@1|root,COG0653@2|Bacteria,1TPEY@1239|Firmicutes,247N2@186801|Clostridia,25VEZ@186806|Eubacteriaceae	186801|Clostridia	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	-	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	Helicase_C,SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
k141_1553_56	97138.C820_00928	6.95e-83	278.0	COG3210@1|root,COG3210@2|Bacteria,1V182@1239|Firmicutes,24BHJ@186801|Clostridia	186801|Clostridia	U	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_1553_57	1122917.KB899681_gene374	7.42e-37	155.0	COG3391@1|root,COG4385@1|root,COG3391@2|Bacteria,COG4385@2|Bacteria,1UZ1H@1239|Firmicutes,4HAFG@91061|Bacilli,26UC4@186822|Paenibacillaceae	91061|Bacilli	S	Phage tail protein (Tail_P2_I)	-	-	-	-	-	-	-	-	-	-	-	-	Tail_P2_I
k141_1553_58	1122917.KB899681_gene375	1.64e-39	164.0	COG3299@1|root,COG3299@2|Bacteria,1UH8J@1239|Firmicutes,4HF47@91061|Bacilli,26U3S@186822|Paenibacillaceae	91061|Bacilli	S	Baseplate J-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Baseplate_J
k141_1553_59	398512.JQKC01000024_gene3230	9.11e-156	494.0	COG3299@1|root,COG3299@2|Bacteria,1TRCX@1239|Firmicutes,24BAX@186801|Clostridia,3WI91@541000|Ruminococcaceae	186801|Clostridia	S	Baseplate J-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Baseplate_J
k141_1553_60	1007103.AFHW01000139_gene1433	1.88e-45	151.0	COG3628@1|root,COG3628@2|Bacteria,1VCD7@1239|Firmicutes,4HKUU@91061|Bacilli,26YDR@186822|Paenibacillaceae	91061|Bacilli	S	Gene 25-like lysozyme	-	-	-	ko:K06903	-	-	-	-	ko00000	-	-	-	GPW_gp25
k141_1553_61	358681.BBR47_42110	2.19e-52	176.0	COG3501@1|root,COG3501@2|Bacteria,1V234@1239|Firmicutes,4HG3D@91061|Bacilli,26URM@186822|Paenibacillaceae	91061|Bacilli	S	Rhs element vgr protein	-	-	-	-	-	-	-	-	-	-	-	-	Phage_base_V
k141_1553_62	1280666.ATVS01000003_gene2166	1.11e-26	117.0	COG3500@1|root,COG3500@2|Bacteria,1V27U@1239|Firmicutes,24GYN@186801|Clostridia,4BY7N@830|Butyrivibrio	186801|Clostridia	S	Late control gene D protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_1553_63	1122917.KB899681_gene380	1.26e-65	208.0	COG1652@1|root,COG1652@2|Bacteria,1V83T@1239|Firmicutes,4HJ06@91061|Bacilli,26VCS@186822|Paenibacillaceae	91061|Bacilli	S	LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	LysM
k141_628_2	202954.BBNK01000001_gene618	0.0001	48.9	COG4968@1|root,COG4968@2|Bacteria,1N6QE@1224|Proteobacteria,1SCBS@1236|Gammaproteobacteria,3NNR0@468|Moraxellaceae	1236|Gammaproteobacteria	NU	Type IV minor pilin ComP, DNA uptake sequence receptor	pilE	-	-	ko:K02655	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	ComP_DUS,N_methyl
k141_2877_1	674977.VMC_38450	8.41e-35	134.0	COG2199@1|root,COG2199@2|Bacteria,1P82T@1224|Proteobacteria,1S7Z1@1236|Gammaproteobacteria,1XVVQ@135623|Vibrionales	135623|Vibrionales	T	Cache domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,dCache_1
k141_2877_2	177437.HRM2_22990	2.28e-39	138.0	COG0834@1|root,COG0834@2|Bacteria,1MV3Q@1224|Proteobacteria,42MKG@68525|delta/epsilon subdivisions,2WJQ7@28221|Deltaproteobacteria,2MJPG@213118|Desulfobacterales	28221|Deltaproteobacteria	ET	Bacterial periplasmic substrate-binding proteins	glnH	-	-	ko:K10036	ko02010,map02010	M00227	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3.2	-	-	SBP_bac_3
k141_3684_1	55601.VANGNB10_cII0535	3.64e-93	288.0	COG1196@1|root,COG3593@1|root,COG1196@2|Bacteria,COG3593@2|Bacteria,1N2CB@1224|Proteobacteria,1RQN2@1236|Gammaproteobacteria,1XSQI@135623|Vibrionales	135623|Vibrionales	L	ATP-dependent endonuclease of the OLD family	ybjD	-	-	ko:K07459	-	-	-	-	ko00000	-	-	-	DUF2813
k141_1995_1	1304885.AUEY01000013_gene3109	5.73e-139	425.0	COG1480@1|root,COG1480@2|Bacteria,1NCY5@1224|Proteobacteria,42MI9@68525|delta/epsilon subdivisions,2WJI1@28221|Deltaproteobacteria,2MI01@213118|Desulfobacterales	28221|Deltaproteobacteria	S	metal-dependent phosphohydrolase 7TM intracellular region	-	-	-	ko:K07037	-	-	-	-	ko00000	-	-	-	7TM-7TMR_HD,7TMR-HDED,HD
k141_1995_2	177437.HRM2_35790	7.44e-38	132.0	COG0319@1|root,COG0319@2|Bacteria,1MZ67@1224|Proteobacteria,42UZ6@68525|delta/epsilon subdivisions,2WQDM@28221|Deltaproteobacteria,2MPVA@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Uncharacterized protein family UPF0054	ybeY	-	-	ko:K07042	-	-	-	-	ko00000,ko03009	-	-	-	UPF0054
k141_4686_1	313595.P700755_003820	6.34e-82	261.0	COG3385@1|root,COG3385@2|Bacteria,4NNZ7@976|Bacteroidetes,1I7YK@117743|Flavobacteriia	976|Bacteroidetes	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
k141_4686_2	1151116.Q7S_17535	1.58e-47	162.0	COG1409@1|root,COG1409@2|Bacteria,1MWKX@1224|Proteobacteria,1RYA3@1236|Gammaproteobacteria,3FF05@34037|Rahnella	1236|Gammaproteobacteria	F	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes	-	-	3.1.4.53	ko:K03651	ko00230,ko02025,map00230,map02025	-	R00191	RC00296	ko00000,ko00001,ko01000	-	-	-	Metallophos
k141_5255_1	338963.Pcar_0832	1.81e-48	179.0	COG3276@1|root,COG3276@2|Bacteria,1MWXH@1224|Proteobacteria,42M49@68525|delta/epsilon subdivisions,2WJ5G@28221|Deltaproteobacteria,43TPN@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Elongation factor SelB winged helix 3	selB	-	-	ko:K03833	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,SelB-wing_2,SelB-wing_3
k141_5255_2	933262.AXAM01000003_gene2874	6.74e-92	288.0	COG5345@1|root,COG5345@2|Bacteria,1MWVH@1224|Proteobacteria,42NJB@68525|delta/epsilon subdivisions,2WM62@28221|Deltaproteobacteria,2MI1G@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Uncharacterized protein conserved in bacteria (DUF2333)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2333
k141_629_1	1379281.AVAG01000092_gene592	2.36e-42	146.0	COG1126@1|root,COG1126@2|Bacteria,1MU9Q@1224|Proteobacteria,42PN3@68525|delta/epsilon subdivisions,2WMAE@28221|Deltaproteobacteria,2MA45@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	ATPases associated with a variety of cellular activities	-	-	3.6.3.21	ko:K02028	-	M00236	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.3	-	-	ABC_tran
k141_629_2	243231.GSU0799	6.67e-133	389.0	COG0765@1|root,COG0765@2|Bacteria,1MWF0@1224|Proteobacteria,42Q80@68525|delta/epsilon subdivisions,2X5YY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	TIGRFAM polar amino acid ABC transporter, inner membrane subunit	-	-	-	ko:K02029	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	BPD_transp_1
k141_629_3	1379281.AVAG01000092_gene594	2.76e-39	138.0	COG0834@1|root,COG0834@2|Bacteria,1R4IH@1224|Proteobacteria,43ATK@68525|delta/epsilon subdivisions,2X67W@28221|Deltaproteobacteria,2MGYC@213115|Desulfovibrionales	28221|Deltaproteobacteria	ET	Ligated ion channel L-glutamate- and glycine-binding site	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
k141_2878_1	1265505.ATUG01000002_gene1232	1.13e-43	146.0	COG0822@1|root,COG0822@2|Bacteria,1N54P@1224|Proteobacteria,42U6Q@68525|delta/epsilon subdivisions,2WQ2X@28221|Deltaproteobacteria,2MKIS@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM nitrogen-fixing NifU domain protein	-	-	-	ko:K04488	-	-	-	-	ko00000	-	-	-	NifU_N
k141_2878_2	1304885.AUEY01000042_gene3585	1.04e-50	166.0	COG1309@1|root,COG1309@2|Bacteria,1RK62@1224|Proteobacteria,42SVK@68525|delta/epsilon subdivisions,2WP42@28221|Deltaproteobacteria,2MK3Q@213118|Desulfobacterales	28221|Deltaproteobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
k141_2568_1	1348635.BBJY01000003_gene3728	2.94e-142	410.0	COG4175@1|root,COG4175@2|Bacteria,1MU86@1224|Proteobacteria,1RN2R@1236|Gammaproteobacteria,1XTVT@135623|Vibrionales	135623|Vibrionales	E	COG4175 ABC-type proline glycine betaine transport system, ATPase component	proV	-	3.6.3.32	ko:K02000	ko02010,map02010	M00208	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.12	-	-	ABC_tran,CBS
k141_2568_2	357804.Ping_0615	3.41e-185	523.0	COG4176@1|root,COG4176@2|Bacteria,1MUM4@1224|Proteobacteria,1RPQS@1236|Gammaproteobacteria,2QJ2G@267894|Psychromonadaceae	1236|Gammaproteobacteria	P	Binding-protein-dependent transport system inner membrane component	proW	GO:0003674,GO:0005215,GO:0005275,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006836,GO:0006950,GO:0006970,GO:0006972,GO:0008150,GO:0009628,GO:0015695,GO:0015696,GO:0015697,GO:0015837,GO:0015838,GO:0015871,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0031460,GO:0032991,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0072337,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990351	-	ko:K02001,ko:K02002	ko02010,map02010	M00208	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	iEcSMS35_1347.EcSMS35_2800	BPD_transp_1
k141_2568_3	55601.VANGNB10_cII0766	0.000162	43.9	COG2113@1|root,COG2113@2|Bacteria,1MWZU@1224|Proteobacteria,1RNDF@1236|Gammaproteobacteria,1XUND@135623|Vibrionales	135623|Vibrionales	E	Substrate binding domain of ABC-type glycine betaine transport system	proX	-	-	ko:K02002	ko02010,map02010	M00208	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	OpuAC
k141_4688_1	1214065.BAGV01000011_gene3181	1.88e-20	92.0	COG4953@1|root,COG4953@2|Bacteria,1MUA9@1224|Proteobacteria,1RMBV@1236|Gammaproteobacteria,283PS@191675|unclassified Enterobacteriaceae	1236|Gammaproteobacteria	M	Penicillin-Binding Protein C-terminus Family	pbpC	-	2.4.1.129	ko:K05367	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	BiPBP_C,Transgly,Transpeptidase
k141_4688_2	1005999.GLGR_0045	5.23e-05	47.0	COG4953@1|root,COG4953@2|Bacteria,1MUA9@1224|Proteobacteria,1RMBV@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	penicillin-binding protein 1C	pbpC	-	2.4.1.129	ko:K05367	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	BiPBP_C,Transgly,Transpeptidase
k141_1555_1	933262.AXAM01000078_gene1603	2.23e-232	669.0	COG0542@1|root,COG0542@2|Bacteria,1MURH@1224|Proteobacteria,42M9S@68525|delta/epsilon subdivisions,2WJSZ@28221|Deltaproteobacteria,2MHW3@213118|Desulfobacterales	28221|Deltaproteobacteria	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
k141_630_1	1265505.ATUG01000001_gene3626	6.25e-100	305.0	COG3894@1|root,COG3894@2|Bacteria,1MX9D@1224|Proteobacteria,42PW1@68525|delta/epsilon subdivisions,2WJZD@28221|Deltaproteobacteria,2MHZX@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Domain of unknown function (DUF4445)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4445
k141_1996_1	1095726.HMPREF1116_1510	0.000705	49.7	COG3440@1|root,COG3440@2|Bacteria,1V6W0@1239|Firmicutes,4HJKE@91061|Bacilli	91061|Bacilli	V	An automated process has identified a potential problem with this gene model	-	-	-	-	-	-	-	-	-	-	-	-	DUF3578,DUF3883
k141_874_1	998088.B565_2798	8.15e-109	332.0	COG0845@1|root,COG0845@2|Bacteria,1MU78@1224|Proteobacteria,1RPI1@1236|Gammaproteobacteria,1Y3S2@135624|Aeromonadales	135624|Aeromonadales	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	acrA	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	Biotin_lipoyl_2,HlyD,HlyD_3,HlyD_D23
k141_874_2	1348635.BBJY01000024_gene2195	0.0	1494.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,1XSPS@135623|Vibrionales	135623|Vibrionales	U	COG0841 Cation multidrug efflux pump	acrB	-	-	ko:K18138	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
k141_874_3	930169.B5T_01647	1.5e-119	366.0	COG1538@1|root,COG1538@2|Bacteria,1MUA8@1224|Proteobacteria,1RMDA@1236|Gammaproteobacteria,1XJGR@135619|Oceanospirillales	135619|Oceanospirillales	MU	Outer membrane efflux protein	-	-	-	ko:K18139	ko01501,ko02024,map01501,map02024	M00642,M00643,M00647,M00718,M00768,M00822	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	1.B.17,2.A.6.2	-	-	OEP
k141_874_4	796620.VIBC2010_00280	2.58e-82	255.0	COG0561@1|root,COG0561@2|Bacteria,1PGMI@1224|Proteobacteria,1RPYI@1236|Gammaproteobacteria,1XV8T@135623|Vibrionales	135623|Vibrionales	S	of the HAD superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
k141_874_6	643562.Daes_3082	3.61e-11	72.8	COG1639@1|root,COG1639@2|Bacteria,1RAH3@1224|Proteobacteria,42PRF@68525|delta/epsilon subdivisions,2WPR9@28221|Deltaproteobacteria,2M7TV@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	PFAM Metal-dependent hydrolase HDOD	-	-	-	-	-	-	-	-	-	-	-	-	HDOD
k141_874_7	55601.VANGNB10_cII0667c	4.91e-61	189.0	COG0784@1|root,COG0784@2|Bacteria,1QV9I@1224|Proteobacteria,1T2AX@1236|Gammaproteobacteria,1XYJB@135623|Vibrionales	135623|Vibrionales	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
k141_874_8	55601.VANGNB10_cII0666c	4.56e-51	167.0	COG1776@1|root,COG1776@2|Bacteria,1RGHM@1224|Proteobacteria,1S5MS@1236|Gammaproteobacteria,1XY74@135623|Vibrionales	135623|Vibrionales	NT	Chemotaxis protein CheC, inhibitor of MCP methylation	-	-	-	ko:K03410	ko02030,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheC
k141_4971_1	1322246.BN4_12708	1.04e-66	228.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42NNT@68525|delta/epsilon subdivisions,2WJDP@28221|Deltaproteobacteria,2M8A1@213115|Desulfovibrionales	28221|Deltaproteobacteria	NT	histidine kinase HAMP region domain protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,DUF3365,HAMP,MCPsignal,dCache_1
k141_4971_3	439235.Dalk_2345	1.85e-87	283.0	COG1538@1|root,COG1538@2|Bacteria,1R8XP@1224|Proteobacteria,42QGI@68525|delta/epsilon subdivisions,2WJH9@28221|Deltaproteobacteria,2MJD1@213118|Desulfobacterales	28221|Deltaproteobacteria	MU	PFAM Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
k141_4971_4	1304885.AUEY01000003_gene501	3.76e-74	242.0	COG0845@1|root,COG0845@2|Bacteria,1MXGH@1224|Proteobacteria,42M4G@68525|delta/epsilon subdivisions,2WKAK@28221|Deltaproteobacteria,2MHPS@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
k141_4971_5	439235.Dalk_2343	8.01e-72	241.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MQ0@68525|delta/epsilon subdivisions,2WISW@28221|Deltaproteobacteria,2MIUG@213118|Desulfobacterales	28221|Deltaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k141_3273_2	1280001.BAOA01000009_gene4129	5.99e-38	129.0	2CJ8F@1|root,32SAV@2|Bacteria,1N0DT@1224|Proteobacteria,1S9BA@1236|Gammaproteobacteria,1XYEK@135623|Vibrionales	135623|Vibrionales	S	YfcL protein	-	-	-	-	-	-	-	-	-	-	-	-	YfcL
k141_3273_3	243277.VC_2113	1.41e-100	294.0	COG3101@1|root,COG3101@2|Bacteria,1MWTG@1224|Proteobacteria,1RNHD@1236|Gammaproteobacteria,1XTN3@135623|Vibrionales	135623|Vibrionales	S	protein conserved in bacteria	yfcM	-	-	ko:K09906	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	EpmC
k141_3273_6	243277.VC_2119	1.86e-103	301.0	COG2840@1|root,COG2840@2|Bacteria,1MVS6@1224|Proteobacteria,1RPXD@1236|Gammaproteobacteria,1XUS2@135623|Vibrionales	135623|Vibrionales	S	Belongs to the UPF0115 family	yfcN	-	-	-	-	-	-	-	-	-	-	-	Smr
k141_3273_8	55601.VANGNB10_cI1927c	1.14e-138	397.0	COG1684@1|root,COG1684@2|Bacteria,1NIF4@1224|Proteobacteria,1RMYW@1236|Gammaproteobacteria,1XTE8@135623|Vibrionales	135623|Vibrionales	N	Role in flagellar biosynthesis	fliR	-	-	ko:K02421	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	Bac_export_1
k141_3273_10	1348635.BBJY01000007_gene252	1.58e-126	369.0	COG1338@1|root,COG1338@2|Bacteria,1MVBU@1224|Proteobacteria,1RMYH@1236|Gammaproteobacteria,1XTA9@135623|Vibrionales	135623|Vibrionales	N	Plays a role in the flagellum-specific transport system	fliP	-	-	ko:K02419	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	FliP
k141_3273_11	675814.VIC_001861	8.05e-37	130.0	COG3190@1|root,COG3190@2|Bacteria,1PQ31@1224|Proteobacteria,1SGKN@1236|Gammaproteobacteria,1XY0C@135623|Vibrionales	135623|Vibrionales	N	COG3190 Flagellar biogenesis protein	fliO	-	-	ko:K02418	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	FliO
k141_3273_13	1348635.BBJY01000007_gene255	4.82e-219	608.0	COG1868@1|root,COG1868@2|Bacteria,1MX01@1224|Proteobacteria,1RQ8M@1236|Gammaproteobacteria,1XTRA@135623|Vibrionales	135623|Vibrionales	N	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation	fliM	-	-	ko:K02416	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliM,FliMN_C
k141_3273_14	945550.VISI1226_11299	5.64e-55	177.0	COG1580@1|root,COG1580@2|Bacteria,1RG10@1224|Proteobacteria,1S7UD@1236|Gammaproteobacteria,1XX17@135623|Vibrionales	135623|Vibrionales	N	Controls the rotational direction of flagella during chemotaxis	fliL	-	-	ko:K02415	-	-	-	-	ko00000,ko02035	-	-	-	FliL
k141_3273_15	945550.VISI1226_11304	3.25e-48	189.0	COG3144@1|root,COG3144@2|Bacteria,1N7XT@1224|Proteobacteria,1SCA6@1236|Gammaproteobacteria,1XSXC@135623|Vibrionales	135623|Vibrionales	N	Flagellar hook-length control protein	fliK	-	-	ko:K02414	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_hook
k141_3273_16	675813.VIB_000774	5.85e-66	204.0	COG2882@1|root,COG2882@2|Bacteria,1NANM@1224|Proteobacteria,1SD9U@1236|Gammaproteobacteria,1XXD9@135623|Vibrionales	135623|Vibrionales	N	COG2882 Flagellar biosynthesis chaperone	fliJ	-	-	ko:K02413	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliJ
k141_3273_17	55601.VANGNB10_cI1936c	2.29e-16	77.8	COG1157@1|root,COG1157@2|Bacteria,1MUH6@1224|Proteobacteria,1RM9W@1236|Gammaproteobacteria,1XTKF@135623|Vibrionales	135623|Vibrionales	NU	COG1157 Flagellar biosynthesis type III secretory pathway ATPase	fliI	-	3.6.3.14	ko:K02412	ko02040,map02040	-	-	-	ko00000,ko00001,ko01000,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	ATP-synt_ab
k141_647_1	1209989.TepiRe1_0129	1.3e-23	104.0	COG1353@1|root,COG1353@2|Bacteria,1UZM3@1239|Firmicutes,24KWD@186801|Clostridia,42FCY@68295|Thermoanaerobacterales	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_3995_2	1190603.AJYD01000023_gene714	8.02e-38	142.0	COG0708@1|root,COG0708@2|Bacteria,1RBRF@1224|Proteobacteria,1S2T0@1236|Gammaproteobacteria,1XVH6@135623|Vibrionales	135623|Vibrionales	L	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
k141_3995_4	675815.VOA_001692	0.0	1459.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,1XV2Y@135623|Vibrionales	135623|Vibrionales	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k141_3995_5	270374.MELB17_22260	1.36e-54	187.0	COG0845@1|root,COG0845@2|Bacteria,1NQZ0@1224|Proteobacteria,1RR67@1236|Gammaproteobacteria,466KI@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
k141_3710_1	1121405.dsmv_2330	5.93e-83	261.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,2MIQF@213118|Desulfobacterales	28221|Deltaproteobacteria	T	response regulator receiver	-	-	-	ko:K02481	-	-	-	-	ko00000,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
k141_3710_2	1337936.IJ00_12005	8.09e-15	79.3	COG4191@1|root,COG4251@1|root,COG4191@2|Bacteria,COG4251@2|Bacteria,1GHC4@1117|Cyanobacteria,1HM56@1161|Nostocales	1117|Cyanobacteria	T	Phytochrome region	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,PAS_2,PHY
k141_900_2	323850.Shew_2209	2.63e-06	56.6	COG1404@1|root,COG3291@1|root,COG4935@1|root,COG1404@2|Bacteria,COG3291@2|Bacteria,COG4935@2|Bacteria,1MU3S@1224|Proteobacteria,1RNB8@1236|Gammaproteobacteria,2QEJS@267890|Shewanellaceae	1236|Gammaproteobacteria	M	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	Big_3_3,PKD,P_proprotein,Peptidase_S8
k141_2900_1	1136163.M565_ctg5P1505	1.13e-31	115.0	COG2153@1|root,COG2153@2|Bacteria,1QJZB@1224|Proteobacteria,1TI1S@1236|Gammaproteobacteria,1XY6B@135623|Vibrionales	135623|Vibrionales	S	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_10
k141_2900_2	358681.BBR47_26970	2.74e-53	170.0	2D6JX@1|root,32TMF@2|Bacteria,1VAZX@1239|Firmicutes,4HW0S@91061|Bacilli,26YNF@186822|Paenibacillaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_1790_2	1385514.N782_07640	4.84e-65	216.0	COG2113@1|root,COG2113@2|Bacteria,1TP82@1239|Firmicutes,4HE25@91061|Bacilli,2YB7B@289201|Pontibacillus	91061|Bacilli	E	ABC transporter substrate-binding protein	-	-	-	ko:K02002	ko02010,map02010	M00208	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	OpuAC
k141_1790_3	1235799.C818_00717	9.68e-35	125.0	COG4087@1|root,COG4087@2|Bacteria,1VA72@1239|Firmicutes,24N3C@186801|Clostridia,27PCV@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Soluble P-type ATPase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase,Hydrolase_3
k141_1790_4	1345695.CLSA_c04600	1.27e-164	495.0	COG3590@1|root,COG3590@2|Bacteria,1TQTA@1239|Firmicutes,2482M@186801|Clostridia,36E8B@31979|Clostridiaceae	186801|Clostridia	O	PFAM peptidase	pepO1	-	-	ko:K07386	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M13,Peptidase_M13_N
k141_1790_5	1340434.AXVA01000026_gene4112	7.81e-120	366.0	COG1473@1|root,COG1473@2|Bacteria,1TQ7B@1239|Firmicutes,4HAIK@91061|Bacilli,1ZDIH@1386|Bacillus	91061|Bacilli	S	amidohydrolase	abgB	-	-	ko:K12941,ko:K21613	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
k141_1790_6	1195246.AGRI_08940	7.75e-15	84.7	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,4664E@72275|Alteromonadaceae	1236|Gammaproteobacteria	T	GGDEF EAL domain-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF,GGDEF,PAS_9
k141_1790_7	935836.JAEL01000165_gene2233	3.38e-50	172.0	COG4326@1|root,COG4326@2|Bacteria,1TPEA@1239|Firmicutes,4HBPW@91061|Bacilli,1ZBFU@1386|Bacillus	91061|Bacilli	S	COG4326 Sporulation control protein	spo0M	-	-	ko:K06377	-	-	-	-	ko00000	-	-	-	Spo0M
k141_1790_8	35841.BT1A1_1169	2.99e-137	410.0	COG1502@1|root,COG1502@2|Bacteria,1TPKY@1239|Firmicutes,4H9TI@91061|Bacilli,1ZBG7@1386|Bacillus	91061|Bacilli	I	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol	cls	GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008808,GO:0009058,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0019637,GO:0030572,GO:0032048,GO:0032049,GO:0032502,GO:0043934,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046471,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:1901576	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2,PLDc_N
k141_156_1	1232437.KL661988_gene231	1.01e-129	384.0	COG1180@1|root,COG1180@2|Bacteria,1QW1I@1224|Proteobacteria,43BRG@68525|delta/epsilon subdivisions,2X72A@28221|Deltaproteobacteria,2MHZ8@213118|Desulfobacterales	28221|Deltaproteobacteria	O	Radical SAM superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
k141_1438_1	1304885.AUEY01000008_gene2102	1.31e-239	674.0	COG0119@1|root,COG0119@2|Bacteria,1MUNQ@1224|Proteobacteria,42MAV@68525|delta/epsilon subdivisions,2WJC9@28221|Deltaproteobacteria,2MIPJ@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Belongs to the alpha-IPM synthase homocitrate synthase family	cimA	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
k141_1438_2	1121405.dsmv_0969	7.48e-200	559.0	COG0059@1|root,COG0059@2|Bacteria,1MV7M@1224|Proteobacteria,42MRS@68525|delta/epsilon subdivisions,2WJW8@28221|Deltaproteobacteria,2MIRN@213118|Desulfobacterales	28221|Deltaproteobacteria	EH	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by	ilvC	-	1.1.1.86	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R03051,R04439,R04440,R05068,R05069,R05071	RC00726,RC00836,RC00837,RC01726	ko00000,ko00001,ko00002,ko01000	-	-	-	IlvC,IlvN
k141_1438_3	96561.Dole_2038	2.96e-68	211.0	COG0440@1|root,COG0440@2|Bacteria,1RAGN@1224|Proteobacteria,42RRU@68525|delta/epsilon subdivisions,2WNBY@28221|Deltaproteobacteria,2MJMK@213118|Desulfobacterales	28221|Deltaproteobacteria	E	TIGRFAM acetolactate synthase, small subunit	ilvN	-	2.2.1.6	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,ACT_5,ALS_ss_C
k141_1438_4	522772.Dacet_0415	5.11e-08	54.3	COG0028@1|root,COG0028@2|Bacteria,2GEK8@200930|Deferribacteres	200930|Deferribacteres	H	Thiamine pyrophosphate enzyme, central domain	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
k141_3793_1	1443125.Z962_06510	0.0	1353.0	COG0046@1|root,COG0047@1|root,COG0151@1|root,COG0046@2|Bacteria,COG0047@2|Bacteria,COG0151@2|Bacteria,1TPAS@1239|Firmicutes,247W2@186801|Clostridia,36UJE@31979|Clostridiaceae	186801|Clostridia	F	phosphoribosylformylglycinamidine synthase	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C,GATase_5
k141_3793_2	1121289.JHVL01000031_gene365	5.51e-148	433.0	COG0151@1|root,COG0151@2|Bacteria,1UHN9@1239|Firmicutes,25E76@186801|Clostridia,36EPV@31979|Clostridiaceae	186801|Clostridia	F	Belongs to the GARS family	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	GARS_A,GARS_C,GARS_N
k141_3793_3	1121324.CLIT_20c00410	3.91e-235	662.0	COG0138@1|root,COG0138@2|Bacteria,1TPQ5@1239|Firmicutes,24AB8@186801|Clostridia,25QUK@186804|Peptostreptococcaceae	186801|Clostridia	F	Bifunctional purine biosynthesis protein PurH	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iHN637.CLJU_RS04230	AICARFT_IMPCHas,MGS
k141_3793_4	1304284.L21TH_1808	2.1e-71	222.0	COG0299@1|root,COG0299@2|Bacteria,1V3RJ@1239|Firmicutes,249JC@186801|Clostridia,36I7J@31979|Clostridiaceae	186801|Clostridia	F	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate	purN	-	2.1.2.2	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS04225	Formyl_trans_N
k141_3793_5	1511.CLOST_0336	1.68e-134	394.0	COG0150@1|root,COG0150@2|Bacteria,1TP9J@1239|Firmicutes,248BT@186801|Clostridia,25QF2@186804|Peptostreptococcaceae	186801|Clostridia	F	Phosphoribosylformylglycinamidine cyclo-ligase	purM	-	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
k141_3793_6	1121324.CLIT_20c00380	5.31e-229	641.0	COG0034@1|root,COG0034@2|Bacteria,1TPH3@1239|Firmicutes,247RF@186801|Clostridia,25QKT@186804|Peptostreptococcaceae	186801|Clostridia	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_6,GATase_7,Pribosyltran
k141_3793_7	1476973.JMMB01000007_gene454	5.83e-109	320.0	COG0152@1|root,COG0152@2|Bacteria,1TP11@1239|Firmicutes,2483I@186801|Clostridia,25RAA@186804|Peptostreptococcaceae	186801|Clostridia	F	Belongs to the SAICAR synthetase family	purC	-	6.3.2.6	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04591	RC00064,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	SAICAR_synt
k141_3793_8	272844.PAB1077	3.84e-54	176.0	COG0041@1|root,arCOG02464@2157|Archaea,2XU0P@28890|Euryarchaeota,24415@183968|Thermococci	183968|Thermococci	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purE	-	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC
k141_3793_9	1121324.CLIT_20c00350	2.59e-209	591.0	COG2252@1|root,COG2252@2|Bacteria,1TQC6@1239|Firmicutes,2483Q@186801|Clostridia,25R1F@186804|Peptostreptococcaceae	186801|Clostridia	S	permease	-	-	-	ko:K06901	-	-	-	-	ko00000,ko02000	2.A.1.40	-	-	Xan_ur_permease
k141_3793_10	1294142.CINTURNW_4055	2.37e-31	122.0	COG3279@1|root,COG3279@2|Bacteria,1V392@1239|Firmicutes,248ZQ@186801|Clostridia,36F65@31979|Clostridiaceae	186801|Clostridia	K	response regulator	agrA	-	-	ko:K07707	ko02020,ko02024,map02020,map02024	M00495	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	LytTR,Response_reg
k141_3793_12	1285586.H131_00506	1.37e-31	121.0	2ASKI@1|root,31I16@2|Bacteria,1V2J9@1239|Firmicutes,4HMKP@91061|Bacilli,3IXQ5@400634|Lysinibacillus	91061|Bacilli	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_3793_13	1347368.HG964406_gene6340	4.07e-164	476.0	COG1106@1|root,COG1106@2|Bacteria,1TPJN@1239|Firmicutes,4HCWK@91061|Bacilli,1ZN35@1386|Bacillus	91061|Bacilli	S	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	-	-	-	-	-	-	-	-	-	AAA_21,AAA_23
k141_3793_14	1321778.HMPREF1982_02509	5.29e-166	476.0	COG1106@1|root,COG1106@2|Bacteria,1TRQ5@1239|Firmicutes,24BS2@186801|Clostridia	186801|Clostridia	S	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K06926	-	-	-	-	ko00000	-	-	-	AAA_21
k141_3793_17	1235802.C823_02022	6.17e-12	73.2	COG4249@1|root,COG4249@2|Bacteria,1V3F2@1239|Firmicutes,24G71@186801|Clostridia	186801|Clostridia	S	Caspase domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C14
k141_3793_19	1391646.AVSU01000015_gene3021	2.42e-292	807.0	COG0519@1|root,COG0519@2|Bacteria,1TPG8@1239|Firmicutes,2487F@186801|Clostridia,25QVV@186804|Peptostreptococcaceae	186801|Clostridia	F	Catalyzes the synthesis of GMP from XMP	guaA	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase,tRNA_Me_trans
k141_3793_20	1121324.CLIT_20c00330	1.1e-266	740.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,1TNZ1@1239|Firmicutes,247PS@186801|Clostridia	186801|Clostridia	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	guaB	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH,NMO
k141_3793_21	1151292.QEW_0223	1.56e-40	139.0	COG1641@1|root,COG1641@2|Bacteria,1V4CM@1239|Firmicutes,24Q1I@186801|Clostridia,25RJ9@186804|Peptostreptococcaceae	186801|Clostridia	S	Protein of unknown function DUF111	-	-	4.99.1.12	ko:K09121	-	-	-	-	ko00000,ko01000	-	-	-	DUF111
k141_3793_22	445973.CLOBAR_00658	4.55e-82	253.0	COG1641@1|root,COG1641@2|Bacteria,1TPAV@1239|Firmicutes,247ZH@186801|Clostridia,25RGQ@186804|Peptostreptococcaceae	186801|Clostridia	S	Protein of unknown function DUF111	larC	-	4.99.1.12	ko:K09121	-	-	-	-	ko00000,ko01000	-	-	-	DUF111
k141_3793_23	536227.CcarbDRAFT_5355	3.24e-94	283.0	COG1691@1|root,COG1691@2|Bacteria,1TP0Z@1239|Firmicutes,24815@186801|Clostridia,36F1K@31979|Clostridiaceae	186801|Clostridia	S	(AIR) carboxylase	-	-	-	ko:K06898	-	-	-	-	ko00000	-	-	-	AIRC
k141_3793_25	1286171.EAL2_c00180	5.73e-75	230.0	COG1573@1|root,COG1573@2|Bacteria,1V267@1239|Firmicutes,24DFW@186801|Clostridia,25YPK@186806|Eubacteriaceae	186801|Clostridia	L	Uracil DNA glycosylase superfamily	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
k141_466_1	439235.Dalk_5190	1.12e-56	193.0	COG3547@1|root,COG3547@2|Bacteria,1NCHY@1224|Proteobacteria,42TM4@68525|delta/epsilon subdivisions,2WR4U@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	PFAM transposase IS116 IS110 IS902 family	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k141_3140_1	56780.SYN_00971	7.55e-39	157.0	COG0840@1|root,COG4191@1|root,COG0840@2|Bacteria,COG4191@2|Bacteria,1MU9B@1224|Proteobacteria,42N03@68525|delta/epsilon subdivisions,2WIX4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	NT	PFAM chemotaxis sensory transducer	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,MCPsignal,dCache_1
k141_158_1	1121451.DESAM_21449	7.17e-61	204.0	COG0438@1|root,COG0438@2|Bacteria,1MWIA@1224|Proteobacteria,42MI7@68525|delta/epsilon subdivisions,2WJS1@28221|Deltaproteobacteria,2MA99@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
k141_4485_2	1298593.TOL_0348	7.95e-15	85.5	COG0582@1|root,COG0582@2|Bacteria,1RAN4@1224|Proteobacteria,1S5SI@1236|Gammaproteobacteria,1XPF9@135619|Oceanospirillales	135619|Oceanospirillales	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
k141_4485_3	1187848.AJYQ01000066_gene3647	3.04e-182	512.0	COG1187@1|root,COG1187@2|Bacteria,1MUCE@1224|Proteobacteria,1RQU0@1236|Gammaproteobacteria,1XUG0@135623|Vibrionales	135623|Vibrionales	J	Belongs to the pseudouridine synthase RsuA family	rluB	GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	5.4.99.22	ko:K06178	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
k141_3509_2	595494.Tola_1705	3.67e-139	406.0	COG0079@1|root,COG0079@2|Bacteria,1MW7I@1224|Proteobacteria,1RQQJ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	decarboxylates L-threonine-O-3-phosphate to yield (R)-1-amino-2-propanol O-2-phosphate, the precursor for the linkage between the nucleotide loop and the corrin ring in cobalamin	cobD	-	4.1.1.81	ko:K04720	ko00860,map00860	-	R06530	RC00517	ko00000,ko00001,ko01000	-	-	-	Aminotran_1_2
k141_3509_3	595494.Tola_1704	2.2e-122	356.0	COG0007@1|root,COG0007@2|Bacteria,1MUI0@1224|Proteobacteria,1RM9V@1236|Gammaproteobacteria,1Y3WC@135624|Aeromonadales	135624|Aeromonadales	H	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme	-	-	2.1.1.107	ko:K02303	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03194	RC00003,RC00871	ko00000,ko00001,ko00002,ko01000	-	-	-	TP_methylase
k141_3509_4	317619.ANKN01000024_gene1610	3.11e-07	53.1	COG0569@1|root,COG0569@2|Bacteria,1GR3U@1117|Cyanobacteria	1117|Cyanobacteria	U	Ion transport protein	-	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans
k141_3509_5	344747.PM8797T_06220	1.27e-53	174.0	COG2126@1|root,COG2126@2|Bacteria,2IZ7U@203682|Planctomycetes	2|Bacteria	J	COG1226 Kef-type K transport systems	-	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans,Ion_trans_2
k141_3509_8	595494.Tola_1681	9.8e-210	593.0	COG1797@1|root,COG1797@2|Bacteria,1MV7Z@1224|Proteobacteria,1RMCU@1236|Gammaproteobacteria	1236|Gammaproteobacteria	H	Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L-glutamine or ammonia as the nitrogen source	cbiA	-	6.3.5.11,6.3.5.9	ko:K02224	ko00860,ko01100,ko01120,map00860,map01100,map01120	-	R05224,R05815	RC00010,RC01301	ko00000,ko00001,ko01000	-	-	-	AAA_26,CbiA,GATase_3
k141_3509_9	595494.Tola_1680	2.74e-139	403.0	COG1270@1|root,COG1270@2|Bacteria,1MURM@1224|Proteobacteria,1RN84@1236|Gammaproteobacteria	1236|Gammaproteobacteria	H	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group	cobD	-	6.3.1.10	ko:K02227	ko00860,ko01100,map00860,map01100	M00122	R06529,R07302	RC00090,RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	CobD_Cbib
k141_3509_10	1453496.AT03_05645	1.45e-90	271.0	COG2082@1|root,COG2082@2|Bacteria,1MX1E@1224|Proteobacteria,1RYUX@1236|Gammaproteobacteria	1236|Gammaproteobacteria	H	Precorrin-8X methylmutase	cobH	-	5.4.99.60,5.4.99.61	ko:K06042	ko00860,ko01100,map00860,map01100	-	R05177,R05814	RC01292,RC01980	ko00000,ko00001,ko01000	-	-	-	CbiC
k141_3509_11	595494.Tola_1678	2.48e-194	548.0	COG1903@1|root,COG1903@2|Bacteria,1MXU3@1224|Proteobacteria,1S016@1236|Gammaproteobacteria	1236|Gammaproteobacteria	H	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A	cbiD	-	2.1.1.195	ko:K02188	ko00860,ko01100,map00860,map01100	-	R07773	RC00003,RC02051	ko00000,ko00001,ko01000	-	-	-	CbiD
k141_3509_12	1214065.BAGV01000015_gene2405	3.76e-62	199.0	COG2241@1|root,COG2241@2|Bacteria	2|Bacteria	H	protein methyltransferase activity	cbiE	-	2.1.1.132,2.1.1.289	ko:K00595,ko:K03399	ko00860,ko01100,map00860,map01100	-	R05149,R05813,R07775	RC00003,RC01279,RC02052,RC02053	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS15725	CbiJ,Met_10,Methyltransf_31,Methyltransf_4,TP_methylase
k141_3509_13	388919.SSA_0469	1.62e-54	178.0	COG2242@1|root,COG2242@2|Bacteria,1TS3H@1239|Firmicutes,4HAP3@91061|Bacilli,1WQP6@1305|Streptococcus sanguinis	91061|Bacilli	H	Cobalt-precorrin-6Y C(15)-methyltransferase	cbiT	-	2.1.1.196	ko:K02191	ko00860,map00860	-	R05813,R07774	RC00003,RC02052,RC02054	ko00000,ko00001,ko01000	-	-	-	GidB,MTS,Methyltransf_31
k141_3509_14	595494.Tola_1675	7.95e-134	385.0	COG2875@1|root,COG2875@2|Bacteria,1MVYY@1224|Proteobacteria,1RWPQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	H	Precorrin-4 C(11)-methyltransferase	cobM	-	2.1.1.133,2.1.1.271	ko:K05936	ko00860,ko01100,map00860,map01100	-	R05181,R05810	RC00003,RC01294,RC02049	ko00000,ko00001,ko01000	-	-	-	TP_methylase
k141_3509_15	595494.Tola_1674	2.17e-122	363.0	COG2073@1|root,COG2073@2|Bacteria,1MWE6@1224|Proteobacteria,1RPWK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	H	Cobalamin biosynthesis protein CbiG	cbiG	-	3.7.1.12	ko:K02189	ko00860,ko01100,map00860,map01100	-	R07772	RC01545,RC02097	ko00000,ko00001,ko01000	-	-	-	CbiG_C,CbiG_N,CbiG_mid
k141_3509_16	35703.DQ02_13505	6.22e-129	371.0	COG1010@1|root,COG1010@2|Bacteria,1MU79@1224|Proteobacteria,1RPC2@1236|Gammaproteobacteria,3WVUR@544|Citrobacter	1236|Gammaproteobacteria	H	Tetrapyrrole (Corrin/Porphyrin) Methylases	cbiH	-	2.1.1.131	ko:K05934	ko00860,ko01100,map00860,map01100	-	R05180,R05809	RC00003,RC01293,RC03471	ko00000,ko00001,ko01000	-	-	-	TP_methylase
k141_3509_17	595494.Tola_1672	4.97e-82	254.0	COG2099@1|root,COG2099@2|Bacteria,1MW48@1224|Proteobacteria,1S0P4@1236|Gammaproteobacteria	1236|Gammaproteobacteria	H	reductase	cobK	-	1.3.1.106,1.3.1.54	ko:K05895	ko00860,ko01100,map00860,map01100	-	R05150,R05812	RC01280	ko00000,ko00001,ko01000	-	-	-	CbiJ
k141_3509_18	1214065.BAGV01000015_gene2399	1.64e-121	354.0	COG4822@1|root,COG4822@2|Bacteria,1P36Y@1224|Proteobacteria,1RYHX@1236|Gammaproteobacteria	1236|Gammaproteobacteria	H	Catalyzes the insertion of Co(2 ) into sirohydrochlorin	cbiK	-	4.99.1.3	ko:K02190	ko00860,ko01100,map00860,map01100	-	R05807	RC01012	ko00000,ko00001,ko01000	-	-	-	CbiK
k141_3509_19	595494.Tola_1670	1.07e-100	299.0	COG2243@1|root,COG2243@2|Bacteria,1MV3G@1224|Proteobacteria,1RNN7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	H	Belongs to the precorrin methyltransferase family	cbiL	-	2.1.1.130,2.1.1.151	ko:K03394	ko00860,ko01100,map00860,map01100	-	R03948,R05808	RC00003,RC01035,RC01662	ko00000,ko00001,ko01000	-	-	-	TP_methylase
k141_3509_20	595494.Tola_1669	3.71e-117	341.0	COG0310@1|root,COG0310@2|Bacteria,1NTQK@1224|Proteobacteria,1RS8D@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import	cbiM	-	-	ko:K02007	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	CbiM
k141_3509_21	1453496.AT03_05700	5.66e-36	124.0	COG1930@1|root,COG1930@2|Bacteria,1RK68@1224|Proteobacteria,1S6AH@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import	cbiN	-	-	ko:K02009	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18	-	-	CbiN
k141_3509_22	1397284.AYMN01000040_gene4344	5.12e-53	177.0	COG0619@1|root,COG0619@2|Bacteria,1R4KM@1224|Proteobacteria,1RQS9@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	cobalt transport protein	cbiQ	-	-	ko:K02008	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	CbiQ
k141_3509_23	28152.DJ57_1769	1.43e-104	311.0	COG1122@1|root,COG1122@2|Bacteria,1N5X0@1224|Proteobacteria,1RRHF@1236|Gammaproteobacteria,41EVF@629|Yersinia	1236|Gammaproteobacteria	P	Part of an ABC transporter complex. Responsible for energy coupling to the transport system	cbiO	-	3.6.3.55	ko:K02006,ko:K06857,ko:K16784	ko02010,map02010	M00186,M00245,M00246,M00581	R10531	RC00002	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.18,3.A.1.22,3.A.1.23,3.A.1.25.1,3.A.1.6.2,3.A.1.6.4	-	-	ABC_tran
k141_3509_24	527002.yaldo0001_10260	1.69e-228	645.0	COG1492@1|root,COG1492@2|Bacteria,1MUFY@1224|Proteobacteria,1RP8G@1236|Gammaproteobacteria,41DWI@629|Yersinia	1236|Gammaproteobacteria	H	Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation	cobQ	-	6.3.5.10	ko:K02232	ko00860,ko01100,map00860,map01100	M00122	R05225	RC00010,RC01302	ko00000,ko00001,ko00002,ko01000	-	-	iYL1228.KPN_03184	AAA_26,CbiA,GATase_3
k141_3509_25	1214065.BAGV01000014_gene3103	5.97e-72	227.0	COG0368@1|root,COG0368@2|Bacteria,1RHCC@1224|Proteobacteria,1S4TE@1236|Gammaproteobacteria	1236|Gammaproteobacteria	H	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate	cobS	GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008818,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016740,GO:0016772,GO:0016780,GO:0017144,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042364,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.8.26	ko:K02233	ko00860,ko01100,map00860,map01100	M00122	R05223,R11174	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CobS
k141_3509_26	595494.Tola_1662	1.38e-149	432.0	COG2038@1|root,COG2038@2|Bacteria,1MVAM@1224|Proteobacteria,1RNPV@1236|Gammaproteobacteria,1Y4CP@135624|Aeromonadales	1236|Gammaproteobacteria	H	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB)	cobT	GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008939,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0017144,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042364,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.4.2.21	ko:K00768	ko00860,ko01100,map00860,map01100	M00122	R04148	RC00033,RC00063	ko00000,ko00001,ko00002,ko01000	-	-	-	DBI_PRT
k141_3509_27	223926.28808842	0.0	1087.0	COG4776@1|root,COG4776@2|Bacteria,1P563@1224|Proteobacteria,1RP5G@1236|Gammaproteobacteria,1XSNX@135623|Vibrionales	135623|Vibrionales	J	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction	rnb	GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0008859,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0140098,GO:1901360,GO:1901361,GO:1901575	3.1.13.1	ko:K01147	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	OB_RNB,RNB,S1
k141_3509_28	1348635.BBJY01000010_gene1340	0.0	895.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,1RMWA@1236|Gammaproteobacteria,1XUDK@135623|Vibrionales	135623|Vibrionales	JKL	DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation	deaD	-	3.6.4.13	ko:K05592	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	DEAD,DbpA,Helicase_C
k141_3509_29	748727.CLJU_c14650	1.73e-36	154.0	COG5001@1|root,COG5001@2|Bacteria,1TP8V@1239|Firmicutes,247PX@186801|Clostridia,36E1W@31979|Clostridiaceae	186801|Clostridia	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	ABC_sub_bind,EAL,GGDEF,HAMP,HisKA_7TM,PAS_3,PAS_9,SBP_bac_3,dCache_1
k141_3509_30	675813.VIB_002778	0.0	1204.0	COG0441@1|root,COG0441@2|Bacteria,1MUP2@1224|Proteobacteria,1RMYE@1236|Gammaproteobacteria,1XVD6@135623|Vibrionales	135623|Vibrionales	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD
k141_3509_31	1348635.BBJY01000010_gene1343	2.15e-87	258.0	COG0290@1|root,COG0290@2|Bacteria,1RDD2@1224|Proteobacteria,1S4E6@1236|Gammaproteobacteria,1XWWZ@135623|Vibrionales	135623|Vibrionales	J	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins	infC	-	-	ko:K02520	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	IF3_C,IF3_N
k141_3509_32	672.VV93_v1c17030	2.94e-36	122.0	COG0291@1|root,COG0291@2|Bacteria,1N6V4@1224|Proteobacteria,1SCHI@1236|Gammaproteobacteria,1XYEU@135623|Vibrionales	135623|Vibrionales	J	Belongs to the bacterial ribosomal protein bL35 family	rpmI	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02916	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L35p
k141_3509_33	29495.EA26_15130	4.5e-71	214.0	COG0292@1|root,COG0292@2|Bacteria,1RGU2@1224|Proteobacteria,1S3P3@1236|Gammaproteobacteria,1XX9W@135623|Vibrionales	135623|Vibrionales	J	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit	rplT	GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02887	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L20
k141_3509_34	1463934.JOCF01000023_gene6190	2.66e-35	142.0	COG0477@1|root,COG2814@2|Bacteria,2I9D5@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator superfamily	setB	-	-	ko:K03291	-	-	-	-	ko00000,ko02000	2.A.1.20	-	-	MFS_1
k141_3509_35	55601.VANGNB10_cII0316	1.24e-80	244.0	COG0454@1|root,COG0456@2|Bacteria,1N4MF@1224|Proteobacteria,1S66R@1236|Gammaproteobacteria,1XWDA@135623|Vibrionales	135623|Vibrionales	K	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
k141_3509_36	1449336.JQLO01000001_gene1809	1.64e-197	571.0	COG1263@1|root,COG1264@1|root,COG2190@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,COG2190@2|Bacteria,1TP5X@1239|Firmicutes,4HC6P@91061|Bacilli	91061|Bacilli	G	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1	-	-	-	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	M00271	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.1.2.11,4.A.1.2.2,4.A.1.2.5,4.A.1.2.6	-	-	PTS_EIIA_1,PTS_EIIB,PTS_EIIC
k141_4834_9	573061.Clocel_1186	1.81e-67	207.0	COG0432@1|root,COG0432@2|Bacteria,1V6J7@1239|Firmicutes,24J8G@186801|Clostridia,36IYZ@31979|Clostridiaceae	186801|Clostridia	S	Secondary thiamine-phosphate synthase enzyme	-	-	-	-	-	-	-	-	-	-	-	-	UPF0047
k141_4834_10	1356852.N008_11730	4.65e-23	112.0	28JDN@1|root,2Z97Y@2|Bacteria,4NKYU@976|Bacteroidetes	976|Bacteroidetes	H	DisA bacterial checkpoint controller nucleotide-binding	-	-	-	-	-	-	-	-	-	-	-	-	DisA_N
k141_4834_11	1321778.HMPREF1982_01510	5.48e-125	373.0	COG0477@1|root,COG2814@2|Bacteria,1UZKT@1239|Firmicutes,25EHZ@186801|Clostridia,26BZA@186813|unclassified Clostridiales	186801|Clostridia	EGP	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
k141_4834_12	86416.Clopa_4742	6.66e-122	354.0	COG3860@1|root,COG3860@2|Bacteria,1TPHH@1239|Firmicutes,248KK@186801|Clostridia,36DNA@31979|Clostridiaceae	186801|Clostridia	K	regulatory protein, LuxR	-	-	-	-	-	-	-	-	-	-	-	-	DUF2087,GerE
k141_4834_14	1209989.TepiRe1_2752	1.64e-40	141.0	COG1853@1|root,COG1853@2|Bacteria,1V4IU@1239|Firmicutes,25B2Z@186801|Clostridia,42HFU@68295|Thermoanaerobacterales	186801|Clostridia	S	Flavin reductase like domain	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
k141_4834_15	484770.UFO1_3492	3.92e-06	49.7	COG0583@1|root,COG0583@2|Bacteria,1TRYW@1239|Firmicutes,4H590@909932|Negativicutes	909932|Negativicutes	K	Transcriptional regulator, LysR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
k141_4834_16	926561.KB900618_gene13	8.15e-122	355.0	COG0627@1|root,COG0627@2|Bacteria,1TPA9@1239|Firmicutes,24F6M@186801|Clostridia,3WC0T@53433|Halanaerobiales	186801|Clostridia	S	Putative esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
k141_4834_17	272562.CA_C1468	7.19e-40	137.0	COG0454@1|root,COG0456@2|Bacteria,1VAFS@1239|Firmicutes,24MUI@186801|Clostridia,36JGA@31979|Clostridiaceae	186801|Clostridia	K	acetyltransferase	-	-	-	ko:K03826	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_10
k141_4834_19	1410653.JHVC01000026_gene303	1.31e-42	148.0	2CD6A@1|root,33WZJ@2|Bacteria,1VW1A@1239|Firmicutes,24JX9@186801|Clostridia,36K20@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_4834_22	411902.CLOBOL_02239	9.79e-60	213.0	COG4870@1|root,COG4870@2|Bacteria,1TVCW@1239|Firmicutes,248WA@186801|Clostridia,21ZAU@1506553|Lachnoclostridium	186801|Clostridia	O	Papain family cysteine protease	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,Cu_amine_oxidN1,Peptidase_C1,Rhodanese
k141_4834_23	180332.JTGN01000007_gene3839	1.26e-84	255.0	COG1395@1|root,COG1395@2|Bacteria,1UY6T@1239|Firmicutes,24FX9@186801|Clostridia	186801|Clostridia	K	helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	Desulfoferrodox,HTH_3
k141_4834_25	573061.Clocel_0184	2.16e-192	536.0	COG1533@1|root,COG1533@2|Bacteria,1TSS2@1239|Firmicutes,248SB@186801|Clostridia,36EMC@31979|Clostridiaceae	186801|Clostridia	L	Radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
k141_4834_26	37659.JNLN01000001_gene1189	1.88e-180	514.0	COG3177@1|root,COG3177@2|Bacteria,1UZBJ@1239|Firmicutes,24M2J@186801|Clostridia	186801|Clostridia	S	Fic/DOC family	-	-	-	-	-	-	-	-	-	-	-	-	Fic
k141_4834_27	1123009.AUID01000014_gene1795	4.71e-94	290.0	COG2944@1|root,COG2944@2|Bacteria,1UZ9K@1239|Firmicutes,25EFY@186801|Clostridia	186801|Clostridia	K	PFAM helix-turn-helix domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF4065,HTH_3,MqsA_antitoxin
k141_3580_3	1265505.ATUG01000001_gene4685	5.12e-24	102.0	COG0820@1|root,COG0820@2|Bacteria,1R67K@1224|Proteobacteria,42PCI@68525|delta/epsilon subdivisions,2WJI5@28221|Deltaproteobacteria,2MIKV@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
k141_4941_1	1304885.AUEY01000001_gene3293	1.15e-108	325.0	COG0500@1|root,COG0640@1|root,COG0640@2|Bacteria,COG2226@2|Bacteria,1NFSV@1224|Proteobacteria,42PGP@68525|delta/epsilon subdivisions,2WMGP@28221|Deltaproteobacteria,2MJCD@213118|Desulfobacterales	28221|Deltaproteobacteria	KQ	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5,Methyltransf_11
k141_4941_2	1304885.AUEY01000001_gene3294	6.66e-220	617.0	COG0499@1|root,COG0499@2|Bacteria,1MUQ2@1224|Proteobacteria,42M83@68525|delta/epsilon subdivisions,2WIZE@28221|Deltaproteobacteria,2MI5G@213118|Desulfobacterales	28221|Deltaproteobacteria	H	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine	ahcY	GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
k141_4627_1	1280671.AUJH01000002_gene1977	1.3e-19	91.7	COG1561@1|root,COG1561@2|Bacteria,1TQHJ@1239|Firmicutes,24824@186801|Clostridia,4BW5I@830|Butyrivibrio	186801|Clostridia	S	Domain of unknown function (DUF1732)	yicC	-	-	-	-	-	-	-	-	-	-	-	DUF1732,YicC_N
k141_4627_2	862908.BMS_1904	8.34e-10	58.5	2CA4A@1|root,32RQK@2|Bacteria,1RE4A@1224|Proteobacteria,42RRI@68525|delta/epsilon subdivisions,2WND4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4416)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4416
k141_264_1	1304885.AUEY01000005_gene830	5.08e-106	315.0	COG2043@1|root,COG2043@2|Bacteria,1RDAZ@1224|Proteobacteria,42S9A@68525|delta/epsilon subdivisions,2WNG5@28221|Deltaproteobacteria,2MKK4@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Uncharacterised ArCR, COG2043	-	-	-	-	-	-	-	-	-	-	-	-	DUF169
k141_549_1	520999.PROVALCAL_03924	1.16e-19	88.2	COG4591@1|root,COG4591@2|Bacteria,1MVV7@1224|Proteobacteria,1RMP9@1236|Gammaproteobacteria,3Z82K@586|Providencia	1236|Gammaproteobacteria	M	COG4591 ABC-type transport system, involved in lipoprotein release, permease component	lolE	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008104,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0032991,GO:0033036,GO:0034613,GO:0044425,GO:0044459,GO:0044464,GO:0044872,GO:0044873,GO:0044874,GO:0051179,GO:0051641,GO:0070727,GO:0071944,GO:0072657,GO:0098796,GO:0098797	-	ko:K09808	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125	-	-	FtsX,MacB_PCD
k141_549_2	55601.VANGNB10_cI1706	1.97e-99	290.0	COG3216@1|root,COG3216@2|Bacteria,1RGV6@1224|Proteobacteria,1S682@1236|Gammaproteobacteria,1XSNS@135623|Vibrionales	135623|Vibrionales	S	protein conserved in bacteria	TLL0138	-	-	ko:K09928	-	-	-	-	ko00000	-	-	-	DUF2062
k141_549_3	29495.EA26_05890	1.72e-170	515.0	COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,1MUKF@1224|Proteobacteria,1RMW6@1236|Gammaproteobacteria,1XVBD@135623|Vibrionales	135623|Vibrionales	S	membrane metal-binding protein	-	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131,Lactamase_B
k141_549_4	675815.VOA_002216	0.0	885.0	COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,1RMUR@1236|Gammaproteobacteria,1XTCT@135623|Vibrionales	135623|Vibrionales	V	Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation	msbA	GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0005488,GO:0005515,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015399,GO:0015405,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0042802,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0071702	-	ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106	-	-	ABC_membrane,ABC_tran
k141_549_5	1188252.AJYK01000023_gene1525	8.59e-145	419.0	COG1663@1|root,COG1663@2|Bacteria,1MU8G@1224|Proteobacteria,1RMMW@1236|Gammaproteobacteria,1XU8K@135623|Vibrionales	135623|Vibrionales	F	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA)	lpxK	GO:0003674,GO:0003824,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009029,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	2.7.1.130	ko:K00912	ko00540,ko01100,map00540,map01100	M00060	R04657	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	LpxK
k141_549_7	55601.VANGNB10_cI1702c	1.37e-137	394.0	COG1212@1|root,COG1212@2|Bacteria,1MUUU@1224|Proteobacteria,1RMAE@1236|Gammaproteobacteria,1XTK4@135623|Vibrionales	135623|Vibrionales	M	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria	kdsB	GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008690,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016772,GO:0016779,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0046401,GO:0070567,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509	2.7.7.38	ko:K00979	ko00540,ko01100,map00540,map01100	M00063	R03351,R11396	RC00152,RC00910	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_3
k141_549_8	945550.VISI1226_19142	0.0	907.0	COG2719@1|root,COG2719@2|Bacteria,1MW6U@1224|Proteobacteria,1RPU2@1236|Gammaproteobacteria,1XTA0@135623|Vibrionales	135623|Vibrionales	S	SpoVR family	ycgB	-	-	-	-	-	-	-	-	-	-	-	SpoVR
k141_549_11	243277.VC_1871	1.62e-86	258.0	COG3013@1|root,COG3013@2|Bacteria,1QWV8@1224|Proteobacteria,1RME1@1236|Gammaproteobacteria,1XU0X@135623|Vibrionales	135623|Vibrionales	S	Belongs to the UPF0304 family	yfbU	-	-	ko:K09161	-	-	-	-	ko00000	-	-	-	YfbU
k141_549_12	1219076.N646_0057	2.12e-150	426.0	COG1180@1|root,COG1180@2|Bacteria,1NQC1@1224|Proteobacteria,1RNCR@1236|Gammaproteobacteria,1XUNS@135623|Vibrionales	135623|Vibrionales	C	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine	pflA	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
k141_549_13	675814.VIC_002638	7.46e-104	307.0	COG3683@1|root,COG3683@2|Bacteria,1R4QA@1224|Proteobacteria,1RQ73@1236|Gammaproteobacteria,1XV9U@135623|Vibrionales	135623|Vibrionales	S	transport system periplasmic component	-	-	-	ko:K06925	-	-	-	-	ko00000,ko03016	-	-	-	DUF1007
k141_549_14	1517681.HW45_08595	6.01e-136	398.0	COG2215@1|root,COG2215@2|Bacteria,1MWIW@1224|Proteobacteria,1RQ9T@1236|Gammaproteobacteria,1XWM6@135623|Vibrionales	135623|Vibrionales	P	Belongs to the NiCoT transporter (TC 2.A.52) family	-	-	-	ko:K08970	-	-	-	-	ko00000,ko02000	2.A.52.2	-	-	NicO
k141_549_15	674977.VMC_31150	0.0	1404.0	COG1882@1|root,COG1882@2|Bacteria,1MWBF@1224|Proteobacteria,1RM96@1236|Gammaproteobacteria,1XT1F@135623|Vibrionales	135623|Vibrionales	C	COG1882 Pyruvate-formate lyase	pflB	-	2.3.1.54	ko:K00656	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	-	R00212,R06987	RC00004,RC01181,RC02742,RC02833	ko00000,ko00001,ko01000	-	-	-	Gly_radical,PFL-like
k141_549_16	675806.VII_001990	2.01e-133	384.0	COG0834@1|root,COG0834@2|Bacteria,1NT2J@1224|Proteobacteria,1S077@1236|Gammaproteobacteria,1XT44@135623|Vibrionales	135623|Vibrionales	ET	COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain	aotJ	-	-	ko:K10022	ko02010,map02010	M00235	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3.11	-	-	SBP_bac_3
k141_549_17	1117318.PRUB_02059	2.64e-160	452.0	COG0708@1|root,COG0708@2|Bacteria,1MVII@1224|Proteobacteria,1RN4H@1236|Gammaproteobacteria,2Q0IV@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	L	COG0708 Exonuclease III	xthA	GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008853,GO:0009987,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
k141_549_18	1116375.VEJY3_18166	1.43e-73	226.0	COG2135@1|root,COG2135@2|Bacteria,1RER4@1224|Proteobacteria,1RSBH@1236|Gammaproteobacteria,1XXM4@135623|Vibrionales	135623|Vibrionales	S	Belongs to the SOS response-associated peptidase family	-	-	-	-	-	-	-	-	-	-	-	-	SRAP
k141_549_19	1219076.N646_0069	6.57e-11	58.2	2EHYU@1|root,33BQB@2|Bacteria,1NGAT@1224|Proteobacteria,1SGE4@1236|Gammaproteobacteria,1XZI3@135623|Vibrionales	135623|Vibrionales	S	Protein of unknown function (DUF2496)	C0585	-	-	-	-	-	-	-	-	-	-	-	DUF2496
k141_549_20	617140.AJZE01000124_gene2659	0.0	919.0	COG1199@1|root,COG1199@2|Bacteria,1MVCU@1224|Proteobacteria,1RMNX@1236|Gammaproteobacteria,1XSN4@135623|Vibrionales	135623|Vibrionales	KL	COG1199 Rad3-related DNA helicases	dinG	-	3.6.4.12	ko:K03722	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD_2,Helicase_C_2,ResIII
k141_549_21	223926.28807465	3.94e-06	56.6	COG3203@1|root,COG3203@2|Bacteria,1QTID@1224|Proteobacteria,1SWVI@1236|Gammaproteobacteria,1XSFV@135623|Vibrionales	135623|Vibrionales	M	COG3203 Outer membrane protein (porin)	ompU	GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944	-	ko:K08720	ko01501,ko05111,map01501,map05111	-	-	-	ko00000,ko00001,ko02000	1.B.1.2.1	-	-	Porin_1,Porin_4
k141_549_23	1122185.N792_12805	3.97e-21	89.4	COG3012@1|root,COG3012@2|Bacteria,1MZZK@1224|Proteobacteria,1S9FV@1236|Gammaproteobacteria,1X7KF@135614|Xanthomonadales	135614|Xanthomonadales	S	Belongs to the UPF0225 family	-	-	-	ko:K09858	-	-	-	-	ko00000	-	-	-	SEC-C
k141_549_24	1348635.BBJY01000013_gene985	6.4e-174	498.0	COG3434@1|root,COG3434@2|Bacteria,1MVW1@1224|Proteobacteria,1RS25@1236|Gammaproteobacteria,1XTJ5@135623|Vibrionales	135623|Vibrionales	T	signal transduction protein containing EAL and modified HD-GYP domains	-	-	-	-	-	-	-	-	-	-	-	-	EAL,HDOD
k141_549_25	1219065.VPR01S_02_02970	2.42e-90	273.0	COG2908@1|root,COG2908@2|Bacteria,1N3U7@1224|Proteobacteria,1RP1X@1236|Gammaproteobacteria,1XSQ8@135623|Vibrionales	135623|Vibrionales	S	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxH	-	3.6.1.54	ko:K03269	ko00540,ko01100,map00540,map01100	M00060	R04549	RC00002	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Metallophos,Metallophos_2
k141_4244_3	1453498.LG45_08850	2.89e-20	96.3	COG3878@1|root,COG3878@2|Bacteria,4NWF1@976|Bacteroidetes,1IIEC@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF1963)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1963
k141_4246_1	1121396.KB893072_gene1222	2.92e-44	163.0	COG0840@1|root,COG5002@1|root,COG0840@2|Bacteria,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,42NK9@68525|delta/epsilon subdivisions,2WMCQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GAF,HAMP,HATPase_c,HisKA,PAS_9,Pkinase,Response_reg,dCache_1
k141_2515_1	1123499.KB908027_gene1904	0.000134	49.7	COG3012@1|root,COG3318@1|root,COG3012@2|Bacteria,COG3318@2|Bacteria,1R4KR@1224|Proteobacteria,2VTNW@28216|Betaproteobacteria,2KRBX@206351|Neisseriales	206351|Neisseriales	U	Psort location Cytoplasmic, score 8.96	-	-	-	ko:K07039	-	-	-	-	ko00000	-	-	-	SEC-C,UPF0149
k141_2515_2	672.VV93_v1c18890	1.92e-186	523.0	COG0042@1|root,COG0042@2|Bacteria,1MUSM@1224|Proteobacteria,1RMMM@1236|Gammaproteobacteria,1XTYF@135623|Vibrionales	135623|Vibrionales	J	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U16 in tRNAs	dusC	-	-	ko:K05541	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Dus
k141_2238_1	547144.HydHO_1305	1.3e-33	127.0	COG1672@1|root,COG1672@2|Bacteria,2G4U4@200783|Aquificae	200783|Aquificae	S	Conserved protein, with A weak D-galactarate dehydratase altronate hydrolase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA-ATPase_like,PDDEXK_9
k141_2238_2	944480.ATUV01000001_gene1228	1.76e-34	134.0	COG1672@1|root,COG1672@2|Bacteria,1N4VD@1224|Proteobacteria,42Y71@68525|delta/epsilon subdivisions,2WTK1@28221|Deltaproteobacteria,2M7JA@213113|Desulfurellales	28221|Deltaproteobacteria	S	Predicted AAA-ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA-ATPase_like,PDDEXK_9
k141_284_1	1432056.X781_360	1.8e-47	166.0	COG1070@1|root,COG1070@2|Bacteria,1PT3G@1224|Proteobacteria,1RRVW@1236|Gammaproteobacteria,1Y7Y5@135625|Pasteurellales	135625|Pasteurellales	G	Belongs to the FGGY kinase family	fucK	-	2.7.1.51	ko:K00879	ko00051,ko01120,map00051,map01120	-	R03241	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	FGGY_C,FGGY_N
k141_284_2	228399.appser1_18040	0.0	1003.0	COG2407@1|root,COG2407@2|Bacteria,1MVD3@1224|Proteobacteria,1RYI3@1236|Gammaproteobacteria,1Y811@135625|Pasteurellales	135625|Pasteurellales	G	Converts the aldose L-fucose into the corresponding ketose L-fuculose	fucI	-	5.3.1.25,5.3.1.3	ko:K01818	ko00051,ko01120,map00051,map01120	-	R03163	RC00434	ko00000,ko00001,ko01000	-	-	-	Fucose_iso_C,Fucose_iso_N1,Fucose_iso_N2
k141_284_3	1005058.UMN179_01241	1.51e-154	446.0	COG0738@1|root,COG0738@2|Bacteria,1MXDC@1224|Proteobacteria,1RQX9@1236|Gammaproteobacteria,1Y7ZB@135625|Pasteurellales	135625|Pasteurellales	G	Major Facilitator Superfamily	fucP	-	-	ko:K02429	-	-	-	-	ko00000,ko02000	2.A.1.7	-	-	MFS_1
k141_571_3	675806.VII_001364	5.27e-70	228.0	COG0501@1|root,COG0501@2|Bacteria,1NK9F@1224|Proteobacteria,1S4XC@1236|Gammaproteobacteria,1XTBD@135623|Vibrionales	135623|Vibrionales	O	Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
k141_803_1	44251.PDUR_06050	8.75e-06	55.8	COG0438@1|root,COG0438@2|Bacteria,1TQN3@1239|Firmicutes,4HCKM@91061|Bacilli,26R4Q@186822|Paenibacillaceae	91061|Bacilli	M	Glycosyl transferase	rfaG1	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
k141_1248_1	1348635.BBJY01000007_gene241	1.33e-263	742.0	COG0665@1|root,COG4121@1|root,COG0665@2|Bacteria,COG4121@2|Bacteria,1MZW5@1224|Proteobacteria,1RMTE@1236|Gammaproteobacteria,1XSRW@135623|Vibrionales	135623|Vibrionales	J	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34	mnmC	GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0003824,GO:0004808,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016491,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0055114,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.1.1.61	ko:K15461	-	-	R00601,R08702	RC00003,RC00053,RC00060,RC01483	ko00000,ko01000,ko03016	-	-	-	DAO,Methyltransf_30
k141_1248_2	55601.VANGNB10_cI1919c	7.32e-45	150.0	COG0431@1|root,COG0431@2|Bacteria,1RH7F@1224|Proteobacteria,1SWZ0@1236|Gammaproteobacteria,1XT0Z@135623|Vibrionales	135623|Vibrionales	S	flavoprotein	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
k141_5202_1	1224318.DT73_04280	2.48e-15	76.6	COG0834@1|root,COG2206@1|root,COG3437@1|root,COG0834@2|Bacteria,COG2206@2|Bacteria,COG3437@2|Bacteria,1MV37@1224|Proteobacteria,1RM9C@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	COG0840 Methyl-accepting chemotaxis protein	-	-	-	-	-	-	-	-	-	-	-	-	HD_5,SBP_bac_3,dCache_1
k141_5202_4	1348635.BBJY01000014_gene904	7.22e-200	565.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,1RMWA@1236|Gammaproteobacteria,1XTY4@135623|Vibrionales	135623|Vibrionales	JKL	Belongs to the DEAD box helicase family	-	-	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
k141_5202_5	1265505.ATUG01000002_gene1296	1.41e-46	157.0	COG2014@1|root,COG2014@2|Bacteria,1RGNW@1224|Proteobacteria,42RPF@68525|delta/epsilon subdivisions,2WNJQ@28221|Deltaproteobacteria,2MM2G@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Putative heavy-metal chelation	-	-	-	ko:K09138	-	-	-	-	ko00000	-	-	-	DUF364,DUF4213
k141_5204_2	1453501.JELR01000002_gene601	1.04e-27	107.0	COG4974@1|root,COG4974@2|Bacteria,1MVAN@1224|Proteobacteria,1S1WF@1236|Gammaproteobacteria,465E7@72275|Alteromonadaceae	1236|Gammaproteobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
k141_3611_1	997884.HMPREF1068_00921	4.88e-89	289.0	COG0826@1|root,COG0826@2|Bacteria,4NEX7@976|Bacteroidetes,2FNE7@200643|Bacteroidia,4AKH4@815|Bacteroidaceae	976|Bacteroidetes	O	Psort location Cytoplasmic, score 8.96	prtQ	-	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	DUF3656,Peptidase_U32
k141_3611_2	1232437.KL662047_gene5145	3.64e-28	124.0	COG3264@1|root,COG4487@1|root,COG3264@2|Bacteria,COG4487@2|Bacteria	2|Bacteria	I	mechanosensitive ion channel activity	mscS	-	-	ko:K05802,ko:K16052,ko:K22051	-	-	-	-	ko00000,ko02000	1.A.23.1.1,1.A.23.1.2,1.A.23.1.3,1.A.23.4	-	-	MS_channel,TM_helix
k141_804_1	663932.KB902575_gene629	2.59e-17	82.4	COG3845@1|root,COG3845@2|Bacteria,1NT0H@1224|Proteobacteria,2UPJ8@28211|Alphaproteobacteria,2JQRR@204441|Rhodospirillales	204441|Rhodospirillales	S	transport systems, ATPase components	-	-	3.6.3.17	ko:K02056	-	M00221	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.2	-	-	ABC_tran
k141_804_2	1348635.BBJY01000005_gene3300	1.33e-95	284.0	COG1309@1|root,COG1309@2|Bacteria,1R4DQ@1224|Proteobacteria,1SYK0@1236|Gammaproteobacteria,1Y2W7@135623|Vibrionales	135623|Vibrionales	K	YcdC-like protein, C-terminal region	-	-	-	ko:K09017	-	-	-	-	ko00000,ko03000	-	-	-	TetR_C_3,TetR_N
k141_1249_1	29495.EA26_15560	3.63e-173	491.0	COG0626@1|root,COG0626@2|Bacteria,1MU9E@1224|Proteobacteria,1RQI0@1236|Gammaproteobacteria,1XSKH@135623|Vibrionales	135623|Vibrionales	E	COG0626 Cystathionine beta-lyases cystathionine gamma-synthases	metC	-	4.4.1.8	ko:K01760	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	M00017	R00782,R01286,R02408,R04941	RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303	ko00000,ko00001,ko00002,ko01000	-	-	-	Cys_Met_Meta_PP
k141_1249_2	1517681.HW45_16650	8.67e-82	248.0	COG2818@1|root,COG2818@2|Bacteria,1R9X5@1224|Proteobacteria,1S25K@1236|Gammaproteobacteria,1XT91@135623|Vibrionales	135623|Vibrionales	L	COG2818 3-methyladenine DNA glycosylase	-	-	3.2.2.20	ko:K01246	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Adenine_glyco
k141_1249_3	1191299.AJYX01000067_gene3868	7.41e-14	67.8	COG1983@1|root,COG1983@2|Bacteria,1N085@1224|Proteobacteria,1S98J@1236|Gammaproteobacteria,1XXB4@135623|Vibrionales	135623|Vibrionales	KT	phage shock protein C	pspC	-	-	ko:K03973	-	-	-	-	ko00000,ko02048,ko03000	-	-	-	PspC
k141_5206_1	879212.DespoDRAFT_00390	1.01e-65	213.0	COG1639@1|root,COG1639@2|Bacteria,1RKNA@1224|Proteobacteria,42TE8@68525|delta/epsilon subdivisions,2WPCE@28221|Deltaproteobacteria,2MPXW@213118|Desulfobacterales	28221|Deltaproteobacteria	T	HDOD domain	-	-	-	-	-	-	-	-	-	-	-	-	HDOD
k141_5206_2	1304885.AUEY01000002_gene421	3.4e-06	47.4	COG2204@1|root,COG2204@2|Bacteria,1READ@1224|Proteobacteria,42RG0@68525|delta/epsilon subdivisions,2WNUN@28221|Deltaproteobacteria,2MJVV@213118|Desulfobacterales	28221|Deltaproteobacteria	T	cheY-homologous receiver domain	-	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
k141_4247_1	1121405.dsmv_3489	7.55e-48	166.0	COG0134@1|root,COG0134@2|Bacteria,1MW5K@1224|Proteobacteria,42MAG@68525|delta/epsilon subdivisions,2WM94@28221|Deltaproteobacteria,2MJFU@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Belongs to the TrpC family	trpC	-	4.1.1.48,5.3.1.24	ko:K01609,ko:K13498	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03508,R03509	RC00944,RC00945	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2494	IGPS
k141_4247_2	1392490.JHZX01000001_gene1078	8.17e-25	104.0	COG0135@1|root,COG0135@2|Bacteria,4NNQ1@976|Bacteroidetes,1I1CD@117743|Flavobacteriia	976|Bacteroidetes	E	Belongs to the TrpF family	trpF	-	5.3.1.24	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03509	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	PRAI
k141_4247_3	1304885.AUEY01000072_gene1708	2.28e-186	528.0	COG0133@1|root,COG0133@2|Bacteria,1MUS8@1224|Proteobacteria,42MIA@68525|delta/epsilon subdivisions,2WJJA@28221|Deltaproteobacteria,2MHP8@213118|Desulfobacterales	28221|Deltaproteobacteria	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB	-	4.2.1.20	ko:K01696,ko:K06001	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
k141_572_1	395961.Cyan7425_2882	1.02e-110	377.0	COG3321@1|root,COG3321@2|Bacteria,1FZXE@1117|Cyanobacteria,3KG6F@43988|Cyanothece	1117|Cyanobacteria	Q	Short-chain dehydrogenase reductase SDR	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N,ADH_zinc_N_2,AMP-binding,Abhydrolase_1,Acyl_transf_1,KAsynt_C_assoc,KR,Ketoacyl-synt_C,Methyltransf_12,PP-binding,PS-DH,Sulfotransfer_3,ketoacyl-synt
k141_1541_1	870967.VIS19158_02550	1.18e-91	278.0	2CCQ9@1|root,2Z7HY@2|Bacteria,1MUWR@1224|Proteobacteria,1RPKI@1236|Gammaproteobacteria,1XVEW@135623|Vibrionales	135623|Vibrionales	S	Phage major capsid protein, P2 family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_cap_P2
k141_1541_2	1187848.AJYQ01000156_gene3821	1.01e-116	343.0	2CAV1@1|root,2ZBY8@2|Bacteria,1RAGI@1224|Proteobacteria,1RYPG@1236|Gammaproteobacteria,1XXR4@135623|Vibrionales	135623|Vibrionales	S	Phage capsid scaffolding protein (GPO) serine peptidase	-	-	-	-	-	-	-	-	-	-	-	-	Phage_GPO
k141_1541_3	870967.VIS19158_02540	0.0	1018.0	COG4373@1|root,COG4373@2|Bacteria,1MXYV@1224|Proteobacteria,1RMCC@1236|Gammaproteobacteria,1XVE2@135623|Vibrionales	135623|Vibrionales	S	Terminase RNaseH-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Terminase_5,Terminase_6,Terminase_6C
k141_1541_4	870967.VIS19158_02535	5.63e-184	517.0	COG4695@1|root,COG4695@2|Bacteria,1MWA5@1224|Proteobacteria,1RPXY@1236|Gammaproteobacteria,1XTHZ@135623|Vibrionales	135623|Vibrionales	S	portal protein	-	-	-	-	-	-	-	-	-	-	-	-	Phage_portal
k141_1541_5	1187848.AJYQ01000156_gene3824	3.91e-97	285.0	2AXCQ@1|root,31PC0@2|Bacteria,1QM29@1224|Proteobacteria,1TJ9M@1236|Gammaproteobacteria,1Y0V0@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_1541_6	1187848.AJYQ01000156_gene3825	4.8e-108	313.0	COG3772@1|root,COG3772@2|Bacteria,1MZJD@1224|Proteobacteria,1S2FS@1236|Gammaproteobacteria,1XXKR@135623|Vibrionales	135623|Vibrionales	G	Phage lysozyme	-	-	-	-	-	-	-	-	-	-	-	-	Phage_lysozyme
k141_3612_2	1219065.VPR01S_13_00380	3.49e-97	290.0	COG3338@1|root,COG3338@2|Bacteria,1PEA6@1224|Proteobacteria,1RSM9@1236|Gammaproteobacteria,1XT7N@135623|Vibrionales	135623|Vibrionales	P	carbonic anhydrase	cah	-	4.2.1.1	ko:K01674	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Carb_anhydrase
k141_3612_3	1280001.BAOA01000026_gene5088	2.07e-35	124.0	COG1057@1|root,COG1057@2|Bacteria,1N1IS@1224|Proteobacteria,1SA2H@1236|Gammaproteobacteria,1XWZ4@135623|Vibrionales	135623|Vibrionales	H	adenylyltransferase	nadD	-	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
k141_5207_1	1219065.VPR01S_05_01290	5.95e-73	242.0	COG4166@1|root,COG4166@2|Bacteria,1MUVU@1224|Proteobacteria,1RMA1@1236|Gammaproteobacteria,1XUMM@135623|Vibrionales	135623|Vibrionales	E	ABC-type oligopeptide transport system, periplasmic component	-	-	-	ko:K13893	ko02010,map02010	M00349	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.21,3.A.1.5.24	-	-	SBP_bac_5
k141_5207_2	266809.PM03_07745	7.67e-24	100.0	COG4174@1|root,COG4174@2|Bacteria,1MVKE@1224|Proteobacteria,2TQJD@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	transport system, permease component	yejB	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006857,GO:0008150,GO:0015833,GO:0015893,GO:0016020,GO:0022857,GO:0035672,GO:0042221,GO:0042493,GO:0042884,GO:0042886,GO:0042891,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944	-	ko:K13894	ko02010,map02010	M00349	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.21,3.A.1.5.24	-	-	BPD_transp_1
k141_2516_1	1209989.TepiRe1_1241	2.09e-33	129.0	COG0707@1|root,COG0707@2|Bacteria,1TQFT@1239|Firmicutes,248IA@186801|Clostridia,42F8I@68295|Thermoanaerobacterales	186801|Clostridia	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
k141_2516_2	177437.HRM2_12700	8.87e-94	292.0	COG0772@1|root,COG0772@2|Bacteria,1MVDB@1224|Proteobacteria,42MG2@68525|delta/epsilon subdivisions,2WJ01@28221|Deltaproteobacteria,2MIUK@213118|Desulfobacterales	28221|Deltaproteobacteria	D	Belongs to the SEDS family	ftsW	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
k141_2516_3	96561.Dole_2789	2.07e-97	307.0	COG0771@1|root,COG0771@2|Bacteria,1MVYD@1224|Proteobacteria,42MJY@68525|delta/epsilon subdivisions,2WJAQ@28221|Deltaproteobacteria,2MHTV@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	AlaDh_PNT_C,FAD_binding_3,Mur_ligase_C,Mur_ligase_M,NAD_binding_8
k141_2516_4	879212.DespoDRAFT_02265	1.32e-114	340.0	COG0472@1|root,COG0472@2|Bacteria,1MUTK@1224|Proteobacteria,42MCP@68525|delta/epsilon subdivisions,2WJDS@28221|Deltaproteobacteria,2MHYY@213118|Desulfobacterales	28221|Deltaproteobacteria	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	-	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	iAF987.Gmet_0409	Glycos_transf_4,MraY_sig1
k141_1542_1	1515746.HR45_09615	1.11e-159	460.0	COG1009@1|root,COG1009@2|Bacteria,1MW2M@1224|Proteobacteria,1RNKN@1236|Gammaproteobacteria,2QA5V@267890|Shewanellaceae	1236|Gammaproteobacteria	CP	NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus	-	-	1.6.5.3	ko:K05577	ko00190,ko01100,map00190,map01100	M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	-	-	-	Proton_antipo_M,Proton_antipo_N
k141_1542_2	1224318.DT73_20970	6.65e-26	106.0	COG3002@1|root,COG3002@2|Bacteria,1MX5K@1224|Proteobacteria,1RQC2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Belongs to the UPF0753 family	-	-	-	ko:K09822	-	-	-	-	ko00000	-	-	-	DUF2309
k141_3613_1	796620.VIBC2010_16499	1.29e-07	51.6	COG3070@1|root,COG3070@2|Bacteria,1RDWD@1224|Proteobacteria,1S496@1236|Gammaproteobacteria,1XUVA@135623|Vibrionales	135623|Vibrionales	K	COG3070 Regulator of competence-specific genes	tfoX	GO:0006810,GO:0007154,GO:0008150,GO:0009290,GO:0009292,GO:0009294,GO:0009605,GO:0009987,GO:0009991,GO:0015931,GO:0030420,GO:0031668,GO:0044764,GO:0050657,GO:0050896,GO:0051027,GO:0051179,GO:0051234,GO:0051704,GO:0051716,GO:0071496,GO:0071702,GO:0071705,GO:0098657	-	ko:K07343	-	-	-	-	ko00000	-	-	-	TfoX_C,TfoX_N
k141_3613_2	314292.VAS14_11429	4.72e-84	259.0	COG0596@1|root,COG0596@2|Bacteria,1R53J@1224|Proteobacteria,1RXY0@1236|Gammaproteobacteria,1XV80@135623|Vibrionales	135623|Vibrionales	S	hydrolases or acyltransferases (alpha beta hydrolase superfamily)	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
k141_5351_2	1304885.AUEY01000039_gene1518	0.0	1118.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,1MV6G@1224|Proteobacteria,42NHZ@68525|delta/epsilon subdivisions,2WJ2H@28221|Deltaproteobacteria,2MJP6@213118|Desulfobacterales	28221|Deltaproteobacteria	E	B12 binding domain	metH	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
k141_4401_1	177437.HRM2_30650	2.27e-53	177.0	COG0330@1|root,COG0330@2|Bacteria,1MV7R@1224|Proteobacteria,42N2V@68525|delta/epsilon subdivisions,2WIPS@28221|Deltaproteobacteria,2MIPC@213118|Desulfobacterales	28221|Deltaproteobacteria	O	HflC and HflK could regulate a protease	hflC	-	-	ko:K04087	-	M00742	-	-	ko00000,ko00002,ko01000	-	-	-	Band_7
k141_4401_2	1232437.KL662039_gene2059	3.63e-112	337.0	COG0330@1|root,COG0330@2|Bacteria,1MUM2@1224|Proteobacteria,42NUT@68525|delta/epsilon subdivisions,2WKQX@28221|Deltaproteobacteria,2MI5I@213118|Desulfobacterales	28221|Deltaproteobacteria	O	HflC and HflK could encode or regulate a protease	hflK	-	-	ko:K04088	-	M00742	-	-	ko00000,ko00002,ko01000	-	-	-	Band_7
k141_5352_1	929558.SMGD1_2545	3.76e-63	221.0	COG2319@1|root,COG4249@1|root,COG2319@2|Bacteria,COG4249@2|Bacteria,1NJ33@1224|Proteobacteria,42PEW@68525|delta/epsilon subdivisions	1224|Proteobacteria	T	Peptidase C14, caspase catalytic	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C14,TIR_2,WD40
k141_3364_1	933262.AXAM01000107_gene1506	1.35e-90	272.0	COG2518@1|root,COG2518@2|Bacteria,1MXQC@1224|Proteobacteria,42QSI@68525|delta/epsilon subdivisions,2WMNJ@28221|Deltaproteobacteria,2MHNG@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	pcm	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
k141_3364_2	1499967.BAYZ01000065_gene6110	6.76e-71	221.0	COG1238@1|root,COG1238@2|Bacteria,2NR6R@2323|unclassified Bacteria	2|Bacteria	S	SNARE associated Golgi protein	MA20_20865	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	SNARE_assoc
k141_5353_1	1319815.HMPREF0202_01822	0.00018	47.0	2E3UH@1|root,32YRV@2|Bacteria	2|Bacteria	S	Tripartite tricarboxylate transporter TctB family	-	-	-	-	-	-	-	-	-	-	-	-	TctB
k141_5354_1	96561.Dole_1658	3.58e-95	286.0	COG1596@1|root,COG1596@2|Bacteria,1N7GP@1224|Proteobacteria,42MNP@68525|delta/epsilon subdivisions,2WMJZ@28221|Deltaproteobacteria,2MJAM@213118|Desulfobacterales	28221|Deltaproteobacteria	M	export protein	wza2	-	-	ko:K01991	ko02026,map02026	-	-	-	ko00000,ko00001,ko02000	1.B.18	-	-	Poly_export,SLBB
k141_4402_1	1051646.VITU9109_25675	1.01e-06	49.7	COG1995@1|root,COG1995@2|Bacteria,1MX5W@1224|Proteobacteria,1RNZV@1236|Gammaproteobacteria,1XT1M@135623|Vibrionales	135623|Vibrionales	H	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)	pdxA	GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	1.1.1.262	ko:K00097	ko00750,ko01100,map00750,map01100	M00124	R05681,R05837,R07406	RC00089,RC00675,RC01475	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxA
k141_4402_2	945543.VIBR0546_05199	4.1e-180	503.0	COG0030@1|root,COG0030@2|Bacteria,1MVNU@1224|Proteobacteria,1RMHW@1236|Gammaproteobacteria,1XTN7@135623|Vibrionales	135623|Vibrionales	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
k141_4402_3	945550.VISI1226_01975	9.64e-142	405.0	COG0639@1|root,COG0639@2|Bacteria,1MV10@1224|Proteobacteria,1RPUJ@1236|Gammaproteobacteria,1XTGT@135623|Vibrionales	135623|Vibrionales	T	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP	apaH	GO:0003674,GO:0003824,GO:0004551,GO:0004721,GO:0006139,GO:0006464,GO:0006470,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008138,GO:0008150,GO:0008152,GO:0008796,GO:0008803,GO:0009987,GO:0015949,GO:0016311,GO:0016462,GO:0016787,GO:0016788,GO:0016791,GO:0016817,GO:0016818,GO:0019538,GO:0034641,GO:0036211,GO:0042578,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044281,GO:0046483,GO:0055086,GO:0071704,GO:0140096,GO:1901360,GO:1901564	3.6.1.41	ko:K01525	ko00230,map00230	-	R00125	RC00002	ko00000,ko00001,ko01000	-	-	-	Metallophos
k141_4402_4	675813.VIB_002094	1.03e-75	230.0	COG0262@1|root,COG0262@2|Bacteria,1RH0P@1224|Proteobacteria,1S5VH@1236|Gammaproteobacteria,1XX0F@135623|Vibrionales	135623|Vibrionales	H	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis	folA	-	1.5.1.3	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	M00126,M00840	R00936,R00937,R00939,R00940,R02235,R02236,R11765	RC00109,RC00110,RC00158	ko00000,ko00001,ko00002,ko01000	-	-	-	DHFR_1
k141_4403_1	243277.VC_2032	4.17e-73	227.0	COG0697@1|root,COG0697@2|Bacteria,1PHRI@1224|Proteobacteria,1RSFS@1236|Gammaproteobacteria,1XURH@135623|Vibrionales	135623|Vibrionales	EG	of the drug metabolite transporter (DMT) superfamily	-	-	-	-	-	-	-	-	-	-	-	-	EamA
k141_4405_1	1265505.ATUG01000001_gene4027	5.66e-214	621.0	COG0784@1|root,COG4191@1|root,COG0784@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42PVE@68525|delta/epsilon subdivisions,2WK31@28221|Deltaproteobacteria,2MPRN@213118|Desulfobacterales	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
k141_5355_1	1304885.AUEY01000036_gene2250	9.94e-208	587.0	COG1109@1|root,COG1109@2|Bacteria,1MUA5@1224|Proteobacteria,42MET@68525|delta/epsilon subdivisions,2WITH@28221|Deltaproteobacteria,2MHR7@213118|Desulfobacterales	28221|Deltaproteobacteria	G	phosphoglucomutase phosphomannomutase alpha beta alpha domain I	algC	-	5.4.2.2,5.4.2.8	ko:K01840,ko:K15778	ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00114	R00959,R01057,R01818,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
k141_5355_2	177437.HRM2_04470	1.69e-27	102.0	COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,42VFG@68525|delta/epsilon subdivisions,2WRYR@28221|Deltaproteobacteria,2MKYK@213118|Desulfobacterales	28221|Deltaproteobacteria	K	Cold shock protein domain	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
k141_5355_3	1304885.AUEY01000095_gene2625	1.29e-251	711.0	COG0210@1|root,COG0210@2|Bacteria,1MU0G@1224|Proteobacteria,42MKU@68525|delta/epsilon subdivisions,2WJR3@28221|Deltaproteobacteria,2MI3D@213118|Desulfobacterales	28221|Deltaproteobacteria	L	UvrD REP helicase	pcrA	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
k141_3365_1	90814.KL370891_gene364	6.91e-38	139.0	COG3177@1|root,COG3177@2|Bacteria,1MV69@1224|Proteobacteria,1RRCR@1236|Gammaproteobacteria,4611I@72273|Thiotrichales	72273|Thiotrichales	S	Adenylyltransferase that mediates the addition of adenosine 5'-monophosphate (AMP) to specific residues of target proteins	-	-	-	-	-	-	-	-	-	-	-	-	Fic,Fic_N
k141_3365_2	1116375.VEJY3_08690	3.28e-183	516.0	COG1879@1|root,COG1879@2|Bacteria,1NZGQ@1224|Proteobacteria,1S7RA@1236|Gammaproteobacteria,1Y1G6@135623|Vibrionales	135623|Vibrionales	K	Bacterial regulatory proteins, lacI family	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_4
k141_3365_3	1116375.VEJY3_08685	1.31e-159	451.0	COG4130@1|root,COG4130@2|Bacteria,1PC6C@1224|Proteobacteria,1RQDK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	isomerase	iolI	-	5.3.99.11	ko:K06606	ko00562,ko01120,map00562,map01120	-	R09952	RC01513	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
k141_3365_5	1116375.VEJY3_08675	9.94e-117	341.0	COG0673@1|root,COG0673@2|Bacteria,1NQ54@1224|Proteobacteria,1RZTE@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose)	iolG	-	1.1.1.18,1.1.1.369	ko:K00010	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	-	R01183,R09951	RC00182	ko00000,ko00001,ko01000	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
k141_4407_1	641107.CDLVIII_5078	1.41e-11	68.2	COG0477@1|root,COG0477@2|Bacteria,1UNMW@1239|Firmicutes	1239|Firmicutes	EGP	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
k141_4407_2	1200792.AKYF01000026_gene37	2.55e-20	87.8	COG3208@1|root,COG3208@2|Bacteria,1V3KR@1239|Firmicutes,4HHC8@91061|Bacilli,26XR6@186822|Paenibacillaceae	91061|Bacilli	Q	thioesterase involved in non-ribosomal peptide biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	Thioesterase
k141_5356_1	1191299.AJYX01000038_gene3445	5.96e-239	662.0	COG1086@1|root,COG1086@2|Bacteria,1MWKY@1224|Proteobacteria,1RYF4@1236|Gammaproteobacteria,1XTR4@135623|Vibrionales	135623|Vibrionales	GM	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt_2
k141_4409_1	111780.Sta7437_3675	1.25e-66	210.0	COG0125@1|root,COG0125@2|Bacteria,1G5JT@1117|Cyanobacteria,3VJ9T@52604|Pleurocapsales	1117|Cyanobacteria	F	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	tmk	GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylate_kin
k141_4409_3	313628.LNTAR_13752	6.58e-11	67.0	COG0207@1|root,COG0207@2|Bacteria	2|Bacteria	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis	thyA	-	2.1.1.45	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	M00053	R02101	RC00219,RC00332	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylat_synt
k141_5357_2	1125863.JAFN01000001_gene1739	9.22e-222	620.0	COG1960@1|root,COG1960@2|Bacteria,1R6R2@1224|Proteobacteria,42NTR@68525|delta/epsilon subdivisions,2WKRA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	acyl-coa dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
k141_5357_3	1304885.AUEY01000069_gene1432	3.49e-33	120.0	COG0789@1|root,COG0789@2|Bacteria,1RITY@1224|Proteobacteria,437AX@68525|delta/epsilon subdivisions,2X2FG@28221|Deltaproteobacteria,2MMG8@213118|Desulfobacterales	28221|Deltaproteobacteria	K	MerR, DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
k141_5358_1	929558.SMGD1_0192	2.85e-07	56.2	COG3829@1|root,COG5001@1|root,COG3829@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,42NJQ@68525|delta/epsilon subdivisions,2YMZP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	hmm pf00563	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_9
k141_5359_1	1238190.AMQY01000017_gene1403	6.75e-27	108.0	COG1024@1|root,COG1024@2|Bacteria,1MVQN@1224|Proteobacteria,1RPE2@1236|Gammaproteobacteria,1XN29@135619|Oceanospirillales	135619|Oceanospirillales	I	Enoyl-CoA hydratase/isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
k141_4410_1	1188252.AJYK01000104_gene20	2e-53	169.0	COG3099@1|root,COG3099@2|Bacteria,1RE1F@1224|Proteobacteria,1S43E@1236|Gammaproteobacteria,1XY16@135623|Vibrionales	135623|Vibrionales	S	Belongs to the UPF0263 family	-	-	-	ko:K09901	-	-	-	-	ko00000	-	-	-	DUF440
k141_4410_2	945550.VISI1226_06224	3.77e-104	304.0	COG0231@1|root,COG0231@2|Bacteria,1MW2J@1224|Proteobacteria,1SZPH@1236|Gammaproteobacteria,1Y2WN@135623|Vibrionales	135623|Vibrionales	J	COG0231 Translation elongation factor P (EF-P) translation initiation factor 5A (eIF-5A)	yeiP	-	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
k141_4410_3	243277.VC_1210	7.92e-61	194.0	COG1708@1|root,COG1708@2|Bacteria,1RID1@1224|Proteobacteria,1S9KW@1236|Gammaproteobacteria,1XTT0@135623|Vibrionales	135623|Vibrionales	S	nucleotidyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_2
k141_3366_3	1265505.ATUG01000002_gene2563	7.58e-85	317.0	COG0454@1|root,COG0503@1|root,COG1040@1|root,COG0456@2|Bacteria,COG0503@2|Bacteria,COG1040@2|Bacteria,1QV41@1224|Proteobacteria,42Q37@68525|delta/epsilon subdivisions,2WKE3@28221|Deltaproteobacteria,2MMN4@213118|Desulfobacterales	28221|Deltaproteobacteria	K	competence protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_5360_1	1127673.GLIP_4298	1.05e-22	110.0	COG0457@1|root,COG0457@2|Bacteria,1MXMD@1224|Proteobacteria,1RSI5@1236|Gammaproteobacteria,46696@72275|Alteromonadaceae	1236|Gammaproteobacteria	G	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_8
k141_5360_2	1195246.AGRI_00720	1.06e-64	218.0	COG5653@1|root,COG5653@2|Bacteria,1RINE@1224|Proteobacteria,1S23E@1236|Gammaproteobacteria,467IB@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_6
k141_5361_1	298386.PBPRB1223	6.49e-90	273.0	COG3335@1|root,COG3415@1|root,COG3335@2|Bacteria,COG3415@2|Bacteria,1Q7PK@1224|Proteobacteria,1RSF0@1236|Gammaproteobacteria,1Y326@135623|Vibrionales	135623|Vibrionales	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,HTH_29,HTH_33
k141_5361_2	857087.Metme_0111	2.44e-45	168.0	COG2202@1|root,COG3447@1|root,COG3614@1|root,COG5001@1|root,COG2202@2|Bacteria,COG3447@2|Bacteria,COG3614@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	CZB,EAL,GAF_2,GGDEF,NMT1,PAS_4,PAS_9,Protoglobin,SBP_bac_3
k141_4412_1	997296.PB1_08512	3.14e-170	534.0	COG2374@1|root,COG4085@1|root,COG2374@2|Bacteria,COG4085@2|Bacteria,1VKCH@1239|Firmicutes,4IS68@91061|Bacilli,1ZS2A@1386|Bacillus	91061|Bacilli	M	Fn3 associated	XK27_02140	-	-	ko:K07004	-	-	-	-	ko00000	-	-	-	CHB_HEX_C_1,Exo_endo_phos,Fn3_assoc,Gram_pos_anchor,LTD,SLH
k141_4412_2	1286171.EAL2_c07320	2.91e-168	476.0	COG0191@1|root,COG0191@2|Bacteria,1TQ01@1239|Firmicutes,248B7@186801|Clostridia,25UWN@186806|Eubacteriaceae	186801|Clostridia	G	Fructose-1,6-bisphosphate aldolase, class II	fba	-	4.1.2.13	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167,M00344,M00345	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	F_bP_aldolase
k141_4413_1	177437.HRM2_00300	1.16e-05	43.9	2ET10@1|root,33KJ8@2|Bacteria,1NM0I@1224|Proteobacteria,42XRS@68525|delta/epsilon subdivisions,2WTDQ@28221|Deltaproteobacteria,2MMCN@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_4413_2	177437.HRM2_32890	9.83e-176	500.0	COG0477@1|root,COG2814@2|Bacteria,1P2GY@1224|Proteobacteria,42MWI@68525|delta/epsilon subdivisions,2WK29@28221|Deltaproteobacteria,2MHKX@213118|Desulfobacterales	28221|Deltaproteobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
k141_5363_1	526222.Desal_3190	2.61e-182	526.0	COG1217@1|root,COG1217@2|Bacteria,1MV5Q@1224|Proteobacteria,42M3S@68525|delta/epsilon subdivisions,2WJVZ@28221|Deltaproteobacteria,2M885@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	elongation factor Tu domain 2 protein	typA	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2
k141_5364_1	1173027.Mic7113_1030	7.53e-26	113.0	COG0515@1|root,COG3899@1|root,COG4191@1|root,COG0515@2|Bacteria,COG3899@2|Bacteria,COG4191@2|Bacteria,1GBKM@1117|Cyanobacteria,1H7D9@1150|Oscillatoriales	1117|Cyanobacteria	KLT	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,AAA_35,GAF,HATPase_c,HisKA,Pkinase
k141_3367_1	345073.VC395_A0656	8.48e-109	323.0	COG0524@1|root,COG0524@2|Bacteria,1MX38@1224|Proteobacteria,1RRWT@1236|Gammaproteobacteria,1XU45@135623|Vibrionales	135623|Vibrionales	G	belongs to the carbohydrate kinase PfkB family	scrK	-	2.7.1.4	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	-	R00760,R00867,R03920	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
k141_3367_2	675813.VIB_002500	3.67e-220	618.0	COG1488@1|root,COG1488@2|Bacteria,1MV8U@1224|Proteobacteria,1RQWS@1236|Gammaproteobacteria,1XSPB@135623|Vibrionales	135623|Vibrionales	F	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP	pncB	GO:0003674,GO:0003824,GO:0004516,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009987,GO:0016874,GO:0016879,GO:0019362,GO:0019637,GO:0019674,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901360,GO:1901564	6.3.4.21	ko:K00763	ko00760,ko01100,map00760,map01100	-	R01724	RC00033	ko00000,ko00001,ko01000	-	-	-	NAPRTase
k141_3367_4	82996.sch_12395	7.4e-138	400.0	COG0667@1|root,COG0667@2|Bacteria,1MV2Y@1224|Proteobacteria,1RPIE@1236|Gammaproteobacteria,4030R@613|Serratia	1236|Gammaproteobacteria	C	aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
k141_5368_1	1121346.KB899815_gene1963	8.55e-16	77.4	COG4191@1|root,COG4191@2|Bacteria,1V42A@1239|Firmicutes,4HHC3@91061|Bacilli,274BQ@186822|Paenibacillaceae	91061|Bacilli	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_7,RsbU_N
k141_4414_4	632245.CLP_0888	1.16e-12	75.1	COG0500@1|root,COG0789@1|root,COG0789@2|Bacteria,COG2226@2|Bacteria,1TSDZ@1239|Firmicutes,248EY@186801|Clostridia,36EQV@31979|Clostridiaceae	186801|Clostridia	KQ	helix_turn_helix, mercury resistance	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1,Methyltransf_11,Methyltransf_25
k141_4414_5	1191299.AJYX01000097_gene1715	9.86e-39	135.0	COG3911@1|root,COG3911@2|Bacteria,1RD7P@1224|Proteobacteria,1S3SW@1236|Gammaproteobacteria,1XUT5@135623|Vibrionales	135623|Vibrionales	S	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_28
k141_3368_2	575788.VS_2019	2.53e-79	239.0	COG0139@1|root,COG0140@1|root,COG0139@2|Bacteria,COG0140@2|Bacteria,1MW67@1224|Proteobacteria,1RMV4@1236|Gammaproteobacteria,1XT5G@135623|Vibrionales	135623|Vibrionales	E	Histidine biosynthesis bifunctional protein HisIE	hisI	GO:0000105,GO:0003674,GO:0003824,GO:0004635,GO:0004636,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016462,GO:0016787,GO:0016810,GO:0016814,GO:0016817,GO:0016818,GO:0018130,GO:0019238,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	3.5.4.19,3.6.1.31	ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04035,R04037	RC00002,RC01055	ko00000,ko00001,ko00002,ko01000	-	-	-	PRA-CH,PRA-PH
k141_3369_1	1121935.AQXX01000140_gene1029	2.29e-43	157.0	COG1879@1|root,COG1879@2|Bacteria,1R6D7@1224|Proteobacteria,1RPMG@1236|Gammaproteobacteria,1XP38@135619|Oceanospirillales	135619|Oceanospirillales	G	Periplasmic binding protein domain	-	-	-	ko:K10439	ko02010,ko02030,map02010,map02030	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	Peripla_BP_4
k141_1381_3	675813.VIB_000817	1.25e-22	89.4	2EGR8@1|root,33AHD@2|Bacteria,1QTRG@1224|Proteobacteria,1SUI3@1236|Gammaproteobacteria,1XYXP@135623|Vibrionales	135623|Vibrionales	S	FeoC like transcriptional regulator	VV1042	-	-	ko:K10123	-	-	-	-	ko00000,ko02000	-	-	-	FeoC
k141_1381_4	1348635.BBJY01000007_gene208	0.0	1134.0	COG0370@1|root,COG0370@2|Bacteria,1MUZC@1224|Proteobacteria,1RME9@1236|Gammaproteobacteria,1XSYA@135623|Vibrionales	135623|Vibrionales	P	transporter of a GTP-driven Fe(2 ) uptake system	feoB	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoB_C,FeoB_N,Gate
k141_1381_5	1348635.BBJY01000007_gene209	9.34e-29	104.0	COG1918@1|root,COG1918@2|Bacteria,1Q29A@1224|Proteobacteria,1SGFM@1236|Gammaproteobacteria,1XYYK@135623|Vibrionales	135623|Vibrionales	P	Fe2 transport system protein A	feoA	-	-	ko:K04758	-	-	-	-	ko00000,ko02000	-	-	-	FeoA
k141_354_1	1205908.AKXW01000008_gene3227	1.73e-107	323.0	COG5421@1|root,COG5421@2|Bacteria,1R25F@1224|Proteobacteria,1RZQP@1236|Gammaproteobacteria,1XV94@135623|Vibrionales	135623|Vibrionales	L	Domain of unknown function (DUF4277)	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DUF4277
k141_36_2	1073999.BN137_286	5.25e-62	199.0	COG3209@1|root,COG3209@2|Bacteria,1MVV1@1224|Proteobacteria,1SKYM@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	COG3209 Rhs family protein	-	-	-	-	-	-	-	-	-	-	-	-	PAAR_motif,RES,RHS,RHS_repeat,Tox-URI2,WHH
k141_36_3	1405.DJ92_223	2.74e-05	48.9	2DP6N@1|root,330S4@2|Bacteria,1V63A@1239|Firmicutes,4HICJ@91061|Bacilli,1ZHUQ@1386|Bacillus	91061|Bacilli	S	SMI1 / KNR4 family	yokK	-	-	-	-	-	-	-	-	-	-	-	SUKH_6
k141_36_4	675813.VIB_002962	0.0	980.0	COG3316@1|root,COG3316@2|Bacteria,1RHKZ@1224|Proteobacteria,1S7XK@1236|Gammaproteobacteria,1Y33H@135623|Vibrionales	135623|Vibrionales	L	Transposase IS66 family	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS66,DDE_Tnp_IS66_C,zf-IS66
k141_36_5	870967.VIS19158_10309	3.11e-63	197.0	COG3436@1|root,COG3436@2|Bacteria,1MZFT@1224|Proteobacteria,1S6DA@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	IS66 Orf2 like	-	-	-	-	-	-	-	-	-	-	-	-	TnpB_IS66
k141_37_1	351746.Pput_5282	2.93e-179	504.0	COG0329@1|root,COG0329@2|Bacteria,1MWAH@1224|Proteobacteria,1S05J@1236|Gammaproteobacteria	1236|Gammaproteobacteria	EM	Belongs to the DapA family	-	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
k141_4100_1	698758.AXY_09310	8.81e-24	102.0	COG0469@1|root,COG0469@2|Bacteria,1TPGG@1239|Firmicutes,4H9VY@91061|Bacilli	91061|Bacilli	G	Belongs to the pyruvate kinase family	pyk	GO:0001871,GO:0003674,GO:0003824,GO:0004743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006116,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019674,GO:0019693,GO:0019752,GO:0030246,GO:0030247,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:2001065	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PEP-utilizers,PK,PK_C
k141_4100_3	983920.Y88_0905	2.58e-120	357.0	COG0148@1|root,COG0148@2|Bacteria,1MU1N@1224|Proteobacteria,2TR04@28211|Alphaproteobacteria,2K00W@204457|Sphingomonadales	204457|Sphingomonadales	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
k141_1732_1	1348635.BBJY01000026_gene2274	1.79e-113	331.0	COG1209@1|root,COG1209@2|Bacteria,1MU0X@1224|Proteobacteria,1RMTR@1236|Gammaproteobacteria,1XU3P@135623|Vibrionales	135623|Vibrionales	H	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis	rmlA	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
k141_1732_3	1136163.M565_ctg4P481	2.25e-258	713.0	COG0677@1|root,COG0677@2|Bacteria,1MUC6@1224|Proteobacteria,1RMX0@1236|Gammaproteobacteria,1XSY5@135623|Vibrionales	135623|Vibrionales	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	-	-	-	-	-	-	-	-	-	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
k141_1732_4	1328313.DS2_07983	6.35e-122	358.0	COG0381@1|root,COG0381@2|Bacteria,1MWZN@1224|Proteobacteria,1RPNC@1236|Gammaproteobacteria,465ED@72275|Alteromonadaceae	1236|Gammaproteobacteria	G	Belongs to the UDP-N-acetylglucosamine 2-epimerase family	wecB	GO:0000271,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0008150,GO:0008152,GO:0008761,GO:0009058,GO:0009059,GO:0009246,GO:0009987,GO:0016051,GO:0016853,GO:0016854,GO:0016857,GO:0033692,GO:0034637,GO:0034645,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046378,GO:0071704,GO:1901135,GO:1901137,GO:1901576	3.2.1.183,5.1.3.14	ko:K01791,ko:K08068	ko00520,ko01100,ko05111,map00520,map01100,map05111	M00362	R00420	RC00290	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	iECOK1_1307.ECOK1_4232,iECS88_1305.ECS88_4208,iECs_1301.ECs4719,iEcSMS35_1347.EcSMS35_4150,iG2583_1286.G2583_4580,iPC815.YPO3864,iSDY_1059.SDY_3962,iSSON_1240.SSON_3958,iUMN146_1321.UM146_19070,iZ_1308.Z5297	Epimerase_2
k141_703_2	1348635.BBJY01000007_gene227	8.82e-108	319.0	COG2267@1|root,COG2267@2|Bacteria,1QUFS@1224|Proteobacteria,1T1XF@1236|Gammaproteobacteria,1XV01@135623|Vibrionales	135623|Vibrionales	I	PGAP1-like protein	-	-	-	ko:K01175	-	-	-	-	ko00000,ko01000	-	-	-	Abhydrolase_1,Abhydrolase_6
k141_703_3	1348635.BBJY01000007_gene226	1.98e-79	241.0	COG3057@1|root,COG3057@2|Bacteria,1MUW8@1224|Proteobacteria,1RQ83@1236|Gammaproteobacteria,1XVQ2@135623|Vibrionales	135623|Vibrionales	L	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated	seqA	GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0006275,GO:0008150,GO:0008156,GO:0009889,GO:0009890,GO:0009892,GO:0010556,GO:0010558,GO:0010605,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0043565,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1990837,GO:2000112,GO:2000113	-	ko:K03645	-	-	-	-	ko00000,ko03032,ko03036	-	-	-	SeqA,SeqA_N
k141_703_4	223926.28805825	0.0	970.0	COG0033@1|root,COG0033@2|Bacteria,1MU5S@1224|Proteobacteria,1RPDV@1236|Gammaproteobacteria,1XT0B@135623|Vibrionales	135623|Vibrionales	G	Phosphoglucomutase	pgm	-	5.4.2.2	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00549	R00959,R01057,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
k141_356_1	439235.Dalk_0874	1.56e-65	219.0	COG0745@1|root,COG1639@1|root,COG0745@2|Bacteria,COG1639@2|Bacteria,1RC5P@1224|Proteobacteria,43AQF@68525|delta/epsilon subdivisions,2X64C@28221|Deltaproteobacteria,2MPGT@213118|Desulfobacterales	28221|Deltaproteobacteria	T	HDOD domain	-	-	-	-	-	-	-	-	-	-	-	-	HDOD,Response_reg
k141_356_2	335543.Sfum_2401	2.41e-36	140.0	COG0784@1|root,COG3829@1|root,COG4191@1|root,COG0784@2|Bacteria,COG3829@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MC4@68525|delta/epsilon subdivisions,2WIZU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,PocR,Response_reg,dCache_1
k141_38_1	617140.AJZE01000132_gene702	4.09e-190	537.0	COG0477@1|root,COG2814@2|Bacteria,1MW19@1224|Proteobacteria,1RVY4@1236|Gammaproteobacteria,1XVE9@135623|Vibrionales	135623|Vibrionales	EGP	Sugar (and other) transporter	-	-	-	ko:K07552	-	-	-	-	ko00000,ko02000	2.A.1.2	-	-	MFS_1
k141_704_1	443144.GM21_1433	1.25e-53	178.0	COG4313@1|root,COG4313@2|Bacteria,1N5E1@1224|Proteobacteria,42U14@68525|delta/epsilon subdivisions,2WQEH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Protein involved in meta-pathway of phenol degradation	-	-	-	-	-	-	-	-	-	-	-	-	Phenol_MetA_deg
k141_705_2	1121396.KB893074_gene3003	1.54e-40	137.0	COG1343@1|root,COG1343@2|Bacteria,1NQEA@1224|Proteobacteria	1224|Proteobacteria	L	CRISPR associated protein Cas2	-	-	-	ko:K09951	-	-	-	-	ko00000,ko02048	-	-	-	CRISPR_Cas2
k141_2734_1	1408422.JHYF01000014_gene176	3.57e-38	132.0	COG0640@1|root,COG0640@2|Bacteria,1VA6G@1239|Firmicutes,24JCN@186801|Clostridia,36JIC@31979|Clostridiaceae	186801|Clostridia	K	Transcriptional regulator	ziaR	-	-	ko:K21903	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5
k141_2734_2	207559.Dde_0132	9.68e-07	51.6	COG0701@1|root,COG0701@2|Bacteria,1MUN8@1224|Proteobacteria,42NHE@68525|delta/epsilon subdivisions,2WJPP@28221|Deltaproteobacteria,2M8KS@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Predicted permease	-	-	-	ko:K07089	-	-	-	-	ko00000	-	-	-	ArsP_1
k141_2734_3	177437.HRM2_16980	2.17e-37	140.0	COG0701@1|root,COG0701@2|Bacteria,1MUN8@1224|Proteobacteria,42NHE@68525|delta/epsilon subdivisions,2WJPP@28221|Deltaproteobacteria,2MIY7@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Predicted permease	-	-	-	ko:K07089	-	-	-	-	ko00000	-	-	-	ArsP_1
k141_1385_2	1123274.KB899416_gene2631	1.47e-148	447.0	COG2304@1|root,COG2304@2|Bacteria	2|Bacteria	IU	oxidoreductase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_2434_58	234831.PSM_A0668	4.91e-83	254.0	COG2356@1|root,COG2356@2|Bacteria,1RI3H@1224|Proteobacteria,1S6A9@1236|Gammaproteobacteria,2Q37C@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	L	Protein of unknown function (DUF1524)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1524
k141_2434_59	945543.VIBR0546_17693	3.76e-169	498.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMV2@1236|Gammaproteobacteria,1XSAN@135623|Vibrionales	135623|Vibrionales	T	methyl-accepting chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal,sCache_2
k141_2434_61	1238450.VIBNISOn1_600027	5.3e-75	230.0	COG1704@1|root,COG1704@2|Bacteria,1MVH0@1224|Proteobacteria,1RP1N@1236|Gammaproteobacteria,1XXK8@135623|Vibrionales	135623|Vibrionales	S	LemA family	-	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
k141_2434_62	1238450.VIBNISOn1_600028	2.96e-107	322.0	COG0457@1|root,COG0457@2|Bacteria,1N9AG@1224|Proteobacteria,1SD5U@1236|Gammaproteobacteria,1XWTW@135623|Vibrionales	135623|Vibrionales	S	Protein of unknown function (DUF3137)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3137
k141_2434_65	525898.Sdel_2203	3.25e-22	95.1	COG3209@1|root,COG3209@2|Bacteria,1QYSZ@1224|Proteobacteria	1224|Proteobacteria	M	Protein of unknown function (DUF1566)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1566
k141_2434_66	945543.VIBR0546_03065	1.13e-174	490.0	COG0625@1|root,COG0625@2|Bacteria,1MUN3@1224|Proteobacteria,1RMF7@1236|Gammaproteobacteria,1XTEP@135623|Vibrionales	135623|Vibrionales	O	Glutathione S-transferase	-	-	-	ko:K11209	-	-	-	-	ko00000,ko01000	-	-	-	GST_C,GST_C_2,GST_N,GST_N_2
k141_2434_67	945543.VIBR0546_14100	2.42e-66	206.0	COG1670@1|root,COG1670@2|Bacteria	2|Bacteria	J	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins	-	-	2.3.1.128	ko:K03790	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_3
k141_1848_1	675816.VIA_000910	8.09e-79	253.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,1MU1Q@1224|Proteobacteria,1RMPS@1236|Gammaproteobacteria,1XTWB@135623|Vibrionales	135623|Vibrionales	H	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	Carb_kinase,YjeF_N
k141_1478_23	1511.CLOST_1309	1.02e-116	344.0	COG0341@1|root,COG0341@2|Bacteria,1UHX8@1239|Firmicutes	1239|Firmicutes	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	-	-	-	ko:K03074	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF
k141_1478_24	445973.CLOBAR_01164	1.23e-171	522.0	COG0608@1|root,COG0608@2|Bacteria,1TPXE@1239|Firmicutes,247NU@186801|Clostridia,25QXQ@186804|Peptostreptococcaceae	186801|Clostridia	L	exonuclease	recJ	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1,ssDNA-exonuc_C
k141_1478_25	1151292.QEW_3360	5.43e-86	256.0	COG0503@1|root,COG0503@2|Bacteria,1V1BV@1239|Firmicutes,24HGX@186801|Clostridia,25RA2@186804|Peptostreptococcaceae	186801|Clostridia	F	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis	apt	-	2.4.2.7	ko:K00759	ko00230,ko01100,map00230,map01100	-	R00190,R01229,R04378	RC00063	ko00000,ko00001,ko01000,ko04147	-	-	-	Pribosyltran
k141_1478_26	1511.CLOST_1305	0.0	1004.0	COG0317@1|root,COG0317@2|Bacteria,1TNYZ@1239|Firmicutes,2489A@186801|Clostridia,25QRM@186804|Peptostreptococcaceae	186801|Clostridia	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	relA	-	2.7.6.5	ko:K00951	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS16615	ACT_4,HD_4,RelA_SpoT,TGS
k141_1478_27	984262.SGRA_1815	2.68e-51	167.0	COG1490@1|root,COG1490@2|Bacteria,4NNFF@976|Bacteroidetes,1ISI6@117747|Sphingobacteriia	976|Bacteroidetes	J	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality	dtd	-	-	ko:K07560	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Tyr_Deacylase
k141_1478_28	632245.CLP_1327	4.03e-51	171.0	COG0491@1|root,COG0491@2|Bacteria,1V6FA@1239|Firmicutes,24JGV@186801|Clostridia,36I3Z@31979|Clostridiaceae	186801|Clostridia	S	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
k141_1478_29	1292035.H476_0482	4.82e-170	494.0	COG0635@1|root,COG0635@2|Bacteria,1TREM@1239|Firmicutes,247JT@186801|Clostridia,25QG9@186804|Peptostreptococcaceae	186801|Clostridia	H	coproporphyrinogen III oxidase	hemZ	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
k141_1478_30	1292035.H476_0484	1.72e-301	837.0	COG0173@1|root,COG0173@2|Bacteria,1TPCN@1239|Firmicutes,247Z3@186801|Clostridia,25QPR@186804|Peptostreptococcaceae	186801|Clostridia	J	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA-synt_2d,tRNA_anti-codon
k141_1478_32	509191.AEDB02000067_gene795	1.24e-28	106.0	COG1937@1|root,COG1937@2|Bacteria,1VEF5@1239|Firmicutes,24QRR@186801|Clostridia,3WJZ3@541000|Ruminococcaceae	186801|Clostridia	S	Metal-sensitive transcriptional repressor	csoR	-	-	ko:K21600	-	-	-	-	ko00000,ko03000	-	-	-	Trns_repr_metal
k141_1478_33	1511.CLOST_1299	2.7e-26	103.0	COG3086@1|root,COG3086@2|Bacteria,1VEYP@1239|Firmicutes,25JYF@186801|Clostridia,25TX2@186804|Peptostreptococcaceae	186801|Clostridia	T	Positive regulator of sigma(E), RseC/MucC	-	-	-	ko:K03803	-	-	-	-	ko00000,ko03021	-	-	-	RseC_MucC
k141_1478_34	1121324.CLIT_23c02060	5.54e-47	156.0	COG3610@1|root,COG3610@2|Bacteria,1V6P0@1239|Firmicutes,24R80@186801|Clostridia,25TPA@186804|Peptostreptococcaceae	186801|Clostridia	S	Putative threonine/serine exporter	-	-	-	-	-	-	-	-	-	-	-	-	ThrE_2
k141_1478_35	1499684.CCNP01000020_gene2448	8.59e-44	155.0	COG2966@1|root,COG2966@2|Bacteria,1TSE8@1239|Firmicutes,24A25@186801|Clostridia,36EA1@31979|Clostridiaceae	186801|Clostridia	S	hmm pf06738	-	-	-	-	-	-	-	-	-	-	-	-	ThrE
k141_1478_36	350688.Clos_1700	2.29e-215	603.0	COG0112@1|root,COG0112@2|Bacteria,1TQVM@1239|Firmicutes,248W5@186801|Clostridia,36EMY@31979|Clostridiaceae	186801|Clostridia	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
k141_1478_37	1408422.JHYF01000001_gene2736	5.76e-76	252.0	COG3829@1|root,COG3829@2|Bacteria,1TP0E@1239|Firmicutes,247MB@186801|Clostridia,36EY7@31979|Clostridiaceae	186801|Clostridia	KT	Bacterial regulatory protein, Fis family	-	-	-	ko:K06714	-	-	-	-	ko00000,ko03000	-	-	-	HTH_8,PAS,PAS_4,PAS_8,PAS_9,Sigma54_activat
k141_1478_38	1476973.JMMB01000007_gene2379	3.19e-135	396.0	COG3457@1|root,COG3457@2|Bacteria,1TNYJ@1239|Firmicutes,248MC@186801|Clostridia,25SQ5@186804|Peptostreptococcaceae	186801|Clostridia	E	Alanine racemase, N-terminal domain	orr	GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006520,GO:0006591,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0019842,GO:0036094,GO:0036361,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0047661,GO:0048037,GO:0050157,GO:0070279,GO:0070280,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901605	5.1.1.12	ko:K21898	ko00472,map00472	-	R00672	RC00302	ko00000,ko00001,ko01000	-	-	-	Ala_racemase_N
k141_1478_39	1499689.CCNN01000009_gene2722	2.88e-249	699.0	COG2978@1|root,COG2978@2|Bacteria,1TPDU@1239|Firmicutes,24BJ1@186801|Clostridia,36DFI@31979|Clostridiaceae	186801|Clostridia	H	AbgT putative transporter family	ydaH	-	-	ko:K12942	-	-	-	-	ko00000	-	-	-	ABG_transport
k141_535_1	1408422.JHYF01000020_gene1828	0.0	1119.0	COG0209@1|root,COG0209@2|Bacteria,1TT3U@1239|Firmicutes,24C4U@186801|Clostridia,36G9Z@31979|Clostridiaceae	186801|Clostridia	F	TIGRFAM ribonucleoside-triphosphate reductase, adenosylcobalamin-dependent	-	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	ATP-cone,Ribonuc_red_lgC
k141_535_2	97139.C824_05297	1.07e-51	175.0	COG0745@1|root,COG0745@2|Bacteria,1TPZ0@1239|Firmicutes,249IC@186801|Clostridia,36EQW@31979|Clostridiaceae	186801|Clostridia	KT	response regulator	srrA_2	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
k141_535_3	1304284.L21TH_1742	4.31e-74	247.0	COG0642@1|root,COG2205@2|Bacteria,1UYC9@1239|Firmicutes,24CPQ@186801|Clostridia,36GIS@31979|Clostridiaceae	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
k141_535_5	941824.TCEL_01741	1.86e-146	449.0	COG0769@1|root,COG0770@1|root,COG0769@2|Bacteria,COG0770@2|Bacteria,1TPQE@1239|Firmicutes,248Q4@186801|Clostridia,36DF8@31979|Clostridiaceae	186801|Clostridia	M	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	-	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
k141_535_6	632292.Calhy_0640	4.42e-86	265.0	COG0253@1|root,COG0253@2|Bacteria,1TPMN@1239|Firmicutes,24AGY@186801|Clostridia,42F7U@68295|Thermoanaerobacterales	186801|Clostridia	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	dapF	-	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	DAP_epimerase
k141_535_8	1121324.CLIT_24c01070	0.0	960.0	COG0480@1|root,COG0480@2|Bacteria,1TPWN@1239|Firmicutes,247N4@186801|Clostridia,25QW4@186804|Peptostreptococcaceae	186801|Clostridia	J	Elongation factor	fusA2	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
k141_535_10	1232449.BAHV02000011_gene2166	6.08e-90	275.0	COG1136@1|root,COG1136@2|Bacteria,1TP6H@1239|Firmicutes,247JJ@186801|Clostridia,26A5Y@186813|unclassified Clostridiales	186801|Clostridia	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
k141_535_11	293826.Amet_0367	8.16e-121	382.0	COG1361@1|root,COG1361@2|Bacteria,1TQHN@1239|Firmicutes,24BUH@186801|Clostridia,36ICF@31979|Clostridiaceae	186801|Clostridia	M	COG NOG29868 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	CARDB
k141_535_12	293826.Amet_0368	4.48e-110	339.0	COG4591@1|root,COG4591@2|Bacteria,1VBN5@1239|Firmicutes,25EBV@186801|Clostridia,36UJS@31979|Clostridiaceae	186801|Clostridia	M	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
k141_535_13	1121324.CLIT_4c00110	5.97e-90	276.0	COG0697@1|root,COG0697@2|Bacteria,1TR1G@1239|Firmicutes,24DN8@186801|Clostridia	186801|Clostridia	EG	PFAM EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
k141_535_14	1499684.CCNP01000018_gene1543	1.1e-122	363.0	COG0206@1|root,COG0206@2|Bacteria,1TP6W@1239|Firmicutes,247Z5@186801|Clostridia,36F0J@31979|Clostridiaceae	186801|Clostridia	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
k141_535_15	1444309.JAQG01000116_gene3093	8.06e-139	412.0	COG3876@1|root,COG3876@2|Bacteria	2|Bacteria	G	Protein conserved in bacteria	ybbC	-	-	-	-	-	-	-	-	-	-	-	Cu_amine_oxidN1,DUF1343,Polysacc_deac_1
k141_535_16	1226325.HMPREF1548_02317	3.7e-17	76.3	COG1925@1|root,COG1925@2|Bacteria	2|Bacteria	G	phosphoenolpyruvate-dependent sugar phosphotransferase system	fryA	-	2.7.3.9	ko:K08483,ko:K11184,ko:K11189,ko:K11201	ko02060,map02060	M00306	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.2.1,8.A.7	-	-	PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C,PTS-HPr,PTS_EIIA_2
k141_535_17	997296.PB1_02105	1.67e-211	607.0	COG1080@1|root,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,4H9VD@91061|Bacilli,1ZAU2@1386|Bacillus	91061|Bacilli	G	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)	ptsI	GO:0006810,GO:0008150,GO:0008643,GO:0009401,GO:0051179,GO:0051234,GO:0071702	2.7.3.9	ko:K08483	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	8.A.7	-	-	PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C
k141_535_18	580331.Thit_1797	1.31e-142	430.0	COG3829@1|root,COG3829@2|Bacteria,1TP0E@1239|Firmicutes,247MB@186801|Clostridia,42F02@68295|Thermoanaerobacterales	186801|Clostridia	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	FeS,Fe_hyd_lg_C,HTH_8,PAS,PAS_9,PTS-HPr,Sigma54_activat
k141_535_20	333138.LQ50_12555	9.52e-192	542.0	COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,4H9RJ@91061|Bacilli,1ZB7V@1386|Bacillus	91061|Bacilli	I	Belongs to the thiolase family	atoB	GO:0003674,GO:0003824,GO:0003988,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016408,GO:0016740,GO:0016746,GO:0016747,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iYO844.BSU24170	Thiolase_C,Thiolase_N
k141_535_21	1121324.CLIT_2c03740	1.12e-146	431.0	COG3858@1|root,COG3858@2|Bacteria,1TQK2@1239|Firmicutes,247YF@186801|Clostridia	186801|Clostridia	M	family 18	ydhD	-	-	-	-	-	-	-	-	-	-	-	CW_binding_2,Cu_amine_oxidN1,Glyco_hydro_18,SH3_3
k141_535_23	251229.Chro_5503	4.53e-58	231.0	COG0515@1|root,COG2203@1|root,COG3899@1|root,COG5001@1|root,COG0515@2|Bacteria,COG2203@2|Bacteria,COG3899@2|Bacteria,COG5001@2|Bacteria,1GIUR@1117|Cyanobacteria,3VIDX@52604|Pleurocapsales	1117|Cyanobacteria	KLT	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GAF,GGDEF,Pkinase
k141_535_24	272562.CA_C2924	3.59e-12	62.0	COG2104@1|root,COG2104@2|Bacteria,1VKB4@1239|Firmicutes,25MYF@186801|Clostridia,36PCS@31979|Clostridiaceae	186801|Clostridia	H	ThiS family	-	-	-	ko:K03154	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
k141_535_25	445973.CLOBAR_01599	7.89e-79	246.0	COG0476@1|root,COG0476@2|Bacteria,1UYFC@1239|Firmicutes,247UZ@186801|Clostridia,25RW4@186804|Peptostreptococcaceae	186801|Clostridia	H	Thiamine biosynthesis protein ThiF	thiF	-	2.7.7.73	ko:K03148	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07459	RC00043	ko00000,ko00001,ko01000	-	-	-	ThiF,ThiS-like
k141_535_26	1121324.CLIT_23c00110	9.82e-122	354.0	COG2022@1|root,COG2022@2|Bacteria,1TQZ1@1239|Firmicutes,247TJ@186801|Clostridia,25QFQ@186804|Peptostreptococcaceae	186801|Clostridia	H	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S	thiG	-	2.8.1.10	ko:K03149	ko00730,ko01100,map00730,map01100	-	R10247	RC03096,RC03097,RC03461	ko00000,ko00001,ko01000	-	-	-	ThiG
k141_535_27	1304880.JAGB01000002_gene1796	2.02e-145	423.0	COG0502@1|root,COG0502@2|Bacteria,1TPEX@1239|Firmicutes,248PF@186801|Clostridia	186801|Clostridia	C	biosynthesis protein ThiH	thiH	-	4.1.99.19	ko:K03150	ko00730,ko01100,map00730,map01100	-	R10246	RC01434,RC03095	ko00000,ko00001,ko01000	-	-	-	BATS,Radical_SAM
k141_535_28	1487921.DP68_10660	2.51e-251	697.0	COG0422@1|root,COG0422@2|Bacteria,1TNZ3@1239|Firmicutes,247JE@186801|Clostridia,36EE1@31979|Clostridiaceae	186801|Clostridia	H	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction	thiC	-	4.1.99.17	ko:K03147	ko00730,ko01100,map00730,map01100	M00127	R03472	RC03251,RC03252	ko00000,ko00001,ko00002,ko01000	-	-	-	ThiC_Rad_SAM
k141_535_29	866895.HBHAL_3422	2.02e-09	62.8	COG0352@1|root,COG0352@2|Bacteria,1V6KJ@1239|Firmicutes,4HIM9@91061|Bacilli,3NFHV@45667|Halobacillus	91061|Bacilli	H	Thiamine monophosphate synthase	tenI	GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.3,5.3.99.10	ko:K00788,ko:K10810	ko00730,ko01100,map00730,map01100	M00127	R03223,R09977,R10712	RC00224,RC02766,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000,ko03000	-	-	-	TMP-TENI
k141_535_30	1235796.C815_01766	1.75e-72	243.0	COG0034@1|root,COG0034@2|Bacteria,1TPH3@1239|Firmicutes	1239|Firmicutes	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	iSB619.SA_RS05225	GATase_6,GATase_7,Pribosyltran
k141_535_31	350688.Clos_0228	1.94e-84	259.0	COG0760@1|root,COG0760@2|Bacteria,1V5Q2@1239|Firmicutes,248JQ@186801|Clostridia,36DDY@31979|Clostridiaceae	186801|Clostridia	O	peptidylprolyl isomerase	prsA2	-	5.2.1.8	ko:K03769,ko:K07533	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3
k141_535_32	880070.Cycma_3683	3.91e-56	213.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,4NDXU@976|Bacteroidetes	976|Bacteroidetes	T	Histidine kinase	-	-	-	ko:K20971	ko02025,map02025	-	-	-	ko00000,ko00001,ko01001,ko02022	-	-	-	7TMR-DISMED2,7TMR-DISM_7TM,HATPase_c,HisKA,PAS_3,PAS_9,Response_reg
k141_535_33	580331.Thit_1844	1.9e-101	335.0	COG3829@1|root,COG4191@1|root,COG3829@2|Bacteria,COG4191@2|Bacteria,1V2NQ@1239|Firmicutes,25KP2@186801|Clostridia,42I7M@68295|Thermoanaerobacterales	186801|Clostridia	T	PFAM ATP-binding region, ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
k141_535_34	1286632.P278_06200	3.3e-11	68.2	COG0745@1|root,COG0745@2|Bacteria,4NQNT@976|Bacteroidetes,1I3AQ@117743|Flavobacteriia	976|Bacteroidetes	T	Response regulator receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
k141_535_35	1121324.CLIT_14c00220	6.78e-43	159.0	COG3437@1|root,COG3437@2|Bacteria,1V6Y5@1239|Firmicutes,24DN3@186801|Clostridia	186801|Clostridia	T	PFAM response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
k141_535_36	1286171.EAL2_c14950	6.16e-95	289.0	COG0583@1|root,COG0583@2|Bacteria,1TSA6@1239|Firmicutes,24BM8@186801|Clostridia,25X2I@186806|Eubacteriaceae	186801|Clostridia	K	LysR substrate binding domain	cmpR	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
k141_535_37	293826.Amet_1379	3.13e-27	107.0	2C1YE@1|root,330PN@2|Bacteria,1VHRZ@1239|Firmicutes,24M1A@186801|Clostridia,36NF5@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_535_38	293826.Amet_4301	9.61e-250	701.0	COG1966@1|root,COG1966@2|Bacteria,1TQN8@1239|Firmicutes,248DZ@186801|Clostridia,36EVZ@31979|Clostridiaceae	186801|Clostridia	T	carbon starvation protein CstA	cstA	-	-	ko:K06200	-	-	-	-	ko00000	-	-	-	CstA,CstA_5TM
k141_535_39	1121289.JHVL01000004_gene2101	6.67e-27	106.0	COG1633@1|root,COG1633@2|Bacteria,1UG7M@1239|Firmicutes,25NGE@186801|Clostridia,36T0K@31979|Clostridiaceae	186801|Clostridia	S	Rubrerythrin	-	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
k141_535_40	517418.Ctha_1418	7.84e-190	538.0	COG0426@1|root,COG0426@2|Bacteria,1FDX4@1090|Chlorobi	1090|Chlorobi	C	PFAM beta-lactamase domain protein	-	-	1.6.3.4	ko:K22405	-	-	-	-	ko00000,ko01000	-	-	-	Flavodoxin_1,Lactamase_B
k141_535_41	293826.Amet_0297	3.36e-62	201.0	COG1360@1|root,COG1360@2|Bacteria,1UXY4@1239|Firmicutes,247RE@186801|Clostridia,36DJJ@31979|Clostridiaceae	186801|Clostridia	N	PFAM OmpA MotB domain protein	motB	-	-	ko:K02557	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	MotB_plug,OmpA
k141_535_42	1121289.JHVL01000029_gene446	2e-82	255.0	COG1291@1|root,COG1291@2|Bacteria,1VUY7@1239|Firmicutes,25DI1@186801|Clostridia,36UBH@31979|Clostridiaceae	186801|Clostridia	N	MotA/TolQ/ExbB proton channel family	-	-	-	ko:K02556	ko02020,ko02030,ko02040,map02020,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	MotA_ExbB
k141_2815_4	326297.Sama_1878	1.53e-169	476.0	COG2801@1|root,COG2801@2|Bacteria,1MVXQ@1224|Proteobacteria,1RR4F@1236|Gammaproteobacteria,2QEPK@267890|Shewanellaceae	1236|Gammaproteobacteria	L	PFAM Integrase, catalytic region	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve
k141_2815_6	1333507.AUTQ01000180_gene1855	0.0	875.0	COG0286@1|root,COG0286@2|Bacteria,1MW3A@1224|Proteobacteria,1RMRA@1236|Gammaproteobacteria,2Q2CY@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	V	HsdM N-terminal domain	hsdM	-	2.1.1.72	ko:K03427	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HsdM_N,N6_Mtase
k141_2815_7	395494.Galf_1413	1.34e-117	355.0	COG0732@1|root,COG0732@2|Bacteria,1R42B@1224|Proteobacteria,2VK3X@28216|Betaproteobacteria	28216|Betaproteobacteria	L	Restriction modification system DNA specificity domain	-	-	3.1.21.3	ko:K01154	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	Methylase_S
k141_2815_8	1333507.AUTQ01000180_gene1853	9.04e-258	723.0	COG2865@1|root,COG2865@2|Bacteria,1MYDU@1224|Proteobacteria,1RNRV@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	transcriptional regulator	-	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AlbA_2,HATPase_c_4
k141_2815_9	1333507.AUTQ01000180_gene1851	0.0	1477.0	COG0610@1|root,COG0610@2|Bacteria,1MU96@1224|Proteobacteria,1RP2Q@1236|Gammaproteobacteria,2Q27V@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	L	Subunit R is required for both nuclease and ATPase activities, but not for modification	-	-	3.1.21.3	ko:K01153	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	EcoR124_C,HSDR_N,NTP_transf_2,ResIII
k141_3864_1	1348635.BBJY01000008_gene1750	4.93e-191	541.0	COG0714@1|root,COG0714@2|Bacteria,1QUGB@1224|Proteobacteria,1T1Y2@1236|Gammaproteobacteria,1XSEK@135623|Vibrionales	135623|Vibrionales	S	ATPase with chaperone activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_3864_2	1348635.BBJY01000008_gene1749	2.13e-109	322.0	COG3745@1|root,COG3745@2|Bacteria,1MW75@1224|Proteobacteria,1S6EP@1236|Gammaproteobacteria,1XT4T@135623|Vibrionales	135623|Vibrionales	U	COG3745 Flp pilus assembly protein CpaB	VV2661	-	-	ko:K02279	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	RcpC,SAF
k141_3864_3	672.VV93_v1c23770	4.13e-227	640.0	COG4964@1|root,COG4964@2|Bacteria,1MV8G@1224|Proteobacteria,1RQ4U@1236|Gammaproteobacteria,1XU4G@135623|Vibrionales	135623|Vibrionales	U	Belongs to the GSP D family	-	-	-	ko:K02280	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	BON,Secretin,T2SS-T3SS_pil_N
k141_3864_4	1136163.M565_ctg1P0205	2.55e-16	73.9	2AWMU@1|root,31NIJ@2|Bacteria,1QK98@1224|Proteobacteria,1TICP@1236|Gammaproteobacteria,1XYVM@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_3864_5	1348635.BBJY01000008_gene1746	1.2e-57	202.0	COG4961@1|root,COG4961@2|Bacteria,1R58C@1224|Proteobacteria,1S1A4@1236|Gammaproteobacteria,1XWG5@135623|Vibrionales	135623|Vibrionales	U	Putative Flp pilus-assembly TadE/G-like	-	-	-	-	-	-	-	-	-	-	-	-	Tad
k141_3864_6	1051646.VITU9109_21844	1.95e-09	60.5	COG4961@1|root,COG4961@2|Bacteria,1NCGE@1224|Proteobacteria,1SDQ1@1236|Gammaproteobacteria,1XXZS@135623|Vibrionales	135623|Vibrionales	U	TadE-like protein	-	-	-	-	-	-	-	-	-	-	-	-	TadE
k141_3864_7	674977.VMC_23990	1.99e-18	85.5	COG4961@1|root,COG4961@2|Bacteria,1PRDK@1224|Proteobacteria,1TC3B@1236|Gammaproteobacteria,1XYH0@135623|Vibrionales	135623|Vibrionales	U	TadE-like protein	VP2414	-	-	-	-	-	-	-	-	-	-	-	TadE
k141_3864_8	1051646.VITU9109_21854	1.56e-137	406.0	COG4963@1|root,COG4963@2|Bacteria,1MWNY@1224|Proteobacteria,1S6CE@1236|Gammaproteobacteria,1XVBI@135623|Vibrionales	135623|Vibrionales	U	COG4963 Flp pilus assembly protein, ATPase CpaE	-	-	-	ko:K02282	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	AAA_31
k141_3864_9	672.VV93_v1c23710	8.8e-100	305.0	COG4962@1|root,COG4962@2|Bacteria,1R7EN@1224|Proteobacteria,1RP9G@1236|Gammaproteobacteria,1XSF1@135623|Vibrionales	135623|Vibrionales	U	COG4962 Flp pilus assembly protein, ATPase CpaF	-	-	-	ko:K02283	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSE
k141_537_1	1232437.KL662016_gene1137	1.33e-85	285.0	COG1391@1|root,COG1391@2|Bacteria,1MU4I@1224|Proteobacteria,42MCT@68525|delta/epsilon subdivisions,2WINW@28221|Deltaproteobacteria,2MHQJ@213118|Desulfobacterales	28221|Deltaproteobacteria	OT	Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell	glnE	-	2.7.7.42,2.7.7.89	ko:K00982	-	-	-	-	ko00000,ko01000	-	-	-	GlnD_UR_UTase,GlnE
k141_1195_1	1348635.BBJY01000004_gene2918	9.7e-68	219.0	COG1566@1|root,COG1566@2|Bacteria,1MU7I@1224|Proteobacteria,1RMAD@1236|Gammaproteobacteria,1XW5D@135623|Vibrionales	135623|Vibrionales	V	COG1566 Multidrug resistance efflux pump	-	-	-	ko:K03543	-	M00701	-	-	ko00000,ko00002,ko02000	8.A.1.1	-	-	Biotin_lipoyl_2,HlyD,HlyD_3,HlyD_D23
k141_3865_1	506534.Rhein_3719	1.18e-29	125.0	COG3419@1|root,COG3419@2|Bacteria,1NUAV@1224|Proteobacteria,1RPV3@1236|Gammaproteobacteria,1WX8M@135613|Chromatiales	135613|Chromatiales	NU	Tfp pilus assembly protein, tip-associated adhesin PilY1	-	-	-	ko:K02674	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	Neisseria_PilC
k141_1196_1	1535422.ND16A_0205	2.9e-38	136.0	COG0597@1|root,COG0597@2|Bacteria,1RGV9@1224|Proteobacteria,1S60E@1236|Gammaproteobacteria,2Q6QV@267889|Colwelliaceae	1236|Gammaproteobacteria	MU	Signal peptidase (SPase) II	lspA	-	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
k141_1196_2	1514668.JOOA01000002_gene3302	9.69e-24	104.0	COG0060@1|root,COG0060@2|Bacteria,1TPS7@1239|Firmicutes,247XX@186801|Clostridia,3WG9B@541000|Ruminococcaceae	186801|Clostridia	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1,zf-FPG_IleRS
k141_4299_3	1191299.AJYX01000052_gene1408	9.93e-225	628.0	COG0617@1|root,COG0617@2|Bacteria,1MU2X@1224|Proteobacteria,1RPFJ@1236|Gammaproteobacteria,1XT9B@135623|Vibrionales	135623|Vibrionales	F	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'- nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases	cca	GO:0003674,GO:0003824,GO:0004652,GO:0004810,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0070566,GO:0071704,GO:0090304,GO:1901360,GO:1990817	2.7.7.72	ko:K00974	ko03013,map03013	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016	-	-	-	HD,PolyA_pol,PolyA_pol_RNAbd
k141_4299_4	1046714.AMRX01000006_gene2618	2.07e-24	105.0	2A9GM@1|root,30YNG@2|Bacteria,1RFB1@1224|Proteobacteria,1SFHS@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_4299_6	1123020.AUIE01000016_gene1943	5.48e-20	84.0	COG2161@1|root,COG2161@2|Bacteria,1N0MZ@1224|Proteobacteria,1SA1X@1236|Gammaproteobacteria	1236|Gammaproteobacteria	D	Antitoxin component of a toxin-antitoxin (TA) module	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
k141_4299_9	945543.VIBR0546_04699	7.08e-113	333.0	COG1694@1|root,COG3956@2|Bacteria,1MVKM@1224|Proteobacteria,1RNVU@1236|Gammaproteobacteria,1XVCP@135623|Vibrionales	135623|Vibrionales	S	Nucleoside triphosphate	mazG	-	3.6.1.9	ko:K04765	ko00230,ko00240,ko00760,ko00770,ko01100,map00230,map00240,map00760,map00770,map01100	-	R00086,R00087,R00103,R00287,R00426,R00515,R00662,R00720,R03004,R03036,R11323	RC00002	ko00000,ko00001,ko01000	-	-	-	MazG
k141_4693_1	1392491.JIAE01000001_gene323	3.03e-21	96.7	COG5016@1|root,COG5016@2|Bacteria,1VT8P@1239|Firmicutes,247NZ@186801|Clostridia,3WH2N@541000|Ruminococcaceae	186801|Clostridia	C	Pyruvate carboxylase, C-terminal domain subunit K01960	pycB	-	4.1.1.3	ko:K01571	ko00620,ko01100,map00620,map01100	-	R00217	RC00040	ko00000,ko00001,ko01000,ko02000	3.B.1.1.1	-	-	HMGL-like,PYC_OADA
k141_4693_3	177437.HRM2_31820	2.38e-276	767.0	COG4799@1|root,COG4799@2|Bacteria,1MVAX@1224|Proteobacteria,43AEE@68525|delta/epsilon subdivisions,2WIRF@28221|Deltaproteobacteria,2MIPI@213118|Desulfobacterales	28221|Deltaproteobacteria	I	PFAM carboxyl transferase	-	-	2.1.3.1,2.1.3.15,6.4.1.3	ko:K01966,ko:K17489	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	M00373,M00741	R00353,R01859	RC00040,RC00097,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
k141_4300_1	710687.KI912270_gene5462	4.3e-23	102.0	COG4251@1|root,COG4251@2|Bacteria,2GK25@201174|Actinobacteria,233P4@1762|Mycobacteriaceae	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,HAMP,HATPase_c,HisKA
k141_4694_1	338963.Pcar_2837	2.27e-91	281.0	COG0330@1|root,COG0330@2|Bacteria,1MWMD@1224|Proteobacteria,42YN9@68525|delta/epsilon subdivisions,2WTT2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	prohibitin homologues	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
k141_2303_1	675806.VII_001963	4.23e-94	283.0	2EC19@1|root,3360G@2|Bacteria,1N87W@1224|Proteobacteria,1S7E3@1236|Gammaproteobacteria,1XSJF@135623|Vibrionales	135623|Vibrionales	S	Peptidoglycan-binding protein, CsiV	pgs1	-	-	-	-	-	-	-	-	-	-	-	CsiV
k141_2882_1	1348635.BBJY01000001_gene2333	3.45e-48	158.0	COG1881@1|root,COG1881@2|Bacteria,1N0Y4@1224|Proteobacteria,1S400@1236|Gammaproteobacteria,1XVBE@135623|Vibrionales	135623|Vibrionales	S	Phosphatidylethanolamine-binding protein	-	-	-	ko:K06910	-	-	-	-	ko00000	-	-	-	PBP
k141_2882_2	1117318.PRUB_12971	1.21e-87	259.0	COG4283@1|root,COG4283@2|Bacteria,1REKU@1224|Proteobacteria,1S4V0@1236|Gammaproteobacteria,2Q4IU@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	S	Protein of unknown function (DUF1706)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1706
k141_4301_1	926559.JoomaDRAFT_3527	3.05e-18	91.3	COG1538@1|root,COG1538@2|Bacteria,4NDZK@976|Bacteroidetes,1I0GP@117743|Flavobacteriia	976|Bacteroidetes	MU	Outer membrane efflux protein	-	-	-	ko:K18139	ko01501,ko02024,map01501,map02024	M00642,M00643,M00647,M00718,M00768,M00822	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	1.B.17,2.A.6.2	-	-	OEP
k141_2883_1	525898.Sdel_2061	6.66e-88	283.0	COG4774@1|root,COG4774@2|Bacteria,1QU2Y@1224|Proteobacteria,43CFU@68525|delta/epsilon subdivisions,2YTF6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	PFAM TonB-dependent Receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	TonB_dep_Rec
k141_4302_1	398512.JQKC01000006_gene804	2.1e-68	221.0	COG0169@1|root,COG0169@2|Bacteria,1TQRY@1239|Firmicutes,2497S@186801|Clostridia,3WGF4@541000|Ruminococcaceae	186801|Clostridia	E	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	aroE	-	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS14365	CM_2,SKI,Shikimate_DH,Shikimate_dh_N
k141_4302_2	1304885.AUEY01000048_gene610	8.68e-32	120.0	COG0077@1|root,COG0077@2|Bacteria,1MU60@1224|Proteobacteria,42MGN@68525|delta/epsilon subdivisions,2WJET@28221|Deltaproteobacteria,2MIFU@213118|Desulfobacterales	28221|Deltaproteobacteria	E	PFAM Prephenate dehydratase	pheA	-	4.2.1.51,5.4.99.5	ko:K14170	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R00691,R01373,R01715	RC00360,RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,CM_2,PDT
k141_1999_1	243277.VC_0732	7.35e-133	382.0	COG0583@1|root,COG0583@2|Bacteria,1MVA1@1224|Proteobacteria,1RPAJ@1236|Gammaproteobacteria,1XSIX@135623|Vibrionales	135623|Vibrionales	K	Transcriptional regulator	-	-	-	ko:K04761	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_1,LysR_substrate
k141_1999_2	672.VV93_v1c06890	1.7e-57	183.0	COG0517@1|root,COG0517@2|Bacteria,1N0EB@1224|Proteobacteria,1S9TG@1236|Gammaproteobacteria,1XX1F@135623|Vibrionales	135623|Vibrionales	S	acetoin utilization protein	-	-	-	-	-	-	-	-	-	-	-	-	CBS
k141_1999_3	1348635.BBJY01000023_gene2002	3.91e-214	595.0	COG0809@1|root,COG0809@2|Bacteria,1MUH3@1224|Proteobacteria,1RMKW@1236|Gammaproteobacteria,1XTWP@135623|Vibrionales	135623|Vibrionales	F	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	queA	GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
k141_1999_5	55601.VANGNB10_cI0657	1.01e-57	180.0	COG1862@1|root,COG1862@2|Bacteria,1MZT2@1224|Proteobacteria,1S9NV@1236|Gammaproteobacteria,1XXBH@135623|Vibrionales	135623|Vibrionales	U	Preprotein translocase subunit YajC	yajC	-	-	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	YajC
k141_1999_6	55601.VANGNB10_cI0658	0.0	1001.0	COG0342@1|root,COG0342@2|Bacteria,1MV5U@1224|Proteobacteria,1RMIQ@1236|Gammaproteobacteria,1XSE8@135623|Vibrionales	135623|Vibrionales	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD-TM1,SecD_SecF,Sec_GG
k141_1999_7	1190606.AJYG01000004_gene829	9.57e-54	178.0	COG0341@1|root,COG0341@2|Bacteria,1MU74@1224|Proteobacteria,1RNTY@1236|Gammaproteobacteria,1XTB0@135623|Vibrionales	135623|Vibrionales	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secF	-	-	ko:K03074	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
k141_2570_1	1238450.VIBNISOn1_1500001	5.73e-152	431.0	COG0175@1|root,COG0175@2|Bacteria,1MXUR@1224|Proteobacteria,1RNC5@1236|Gammaproteobacteria,1XTU8@135623|Vibrionales	135623|Vibrionales	EH	Belongs to the PAPS reductase family. CysH subfamily	cysH	GO:0003674,GO:0003824,GO:0004604,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006790,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016667,GO:0016671,GO:0044237,GO:0044424,GO:0044464,GO:0055114	1.8.4.10,1.8.4.8	ko:K00390	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00176	R02021	RC00007,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	-	PAPS_reduct
k141_2570_3	29495.EA26_02520	0.0	929.0	COG0369@1|root,COG0369@2|Bacteria,1QUAH@1224|Proteobacteria,1T1RJ@1236|Gammaproteobacteria,1XT6J@135623|Vibrionales	135623|Vibrionales	P	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component	cysJ	-	1.8.1.2	ko:K00380	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00176	R00858	RC00065	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_1,Flavodoxin_1,NAD_binding_1
k141_2570_4	1187848.AJYQ01000095_gene1813	8.54e-31	110.0	2C2GZ@1|root,2ZHSS@2|Bacteria,1P942@1224|Proteobacteria,1STTI@1236|Gammaproteobacteria,1XYB8@135623|Vibrionales	135623|Vibrionales	-	-	VV2968	-	-	-	-	-	-	-	-	-	-	-	-
k141_2570_5	1219065.VPR01S_31_00170	2.46e-210	585.0	COG0042@1|root,COG0042@2|Bacteria,1MUY1@1224|Proteobacteria,1RN28@1236|Gammaproteobacteria,1XUYB@135623|Vibrionales	135623|Vibrionales	J	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs	dusA	-	-	ko:K05539	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Dus
k141_2570_6	1278307.KB906995_gene2948	7.34e-190	535.0	COG0582@1|root,COG0582@2|Bacteria,1NWGS@1224|Proteobacteria,1S4PB@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
k141_2571_2	469618.FVAG_02340	2.87e-63	201.0	COG0388@1|root,COG0388@2|Bacteria,379CK@32066|Fusobacteria	32066|Fusobacteria	S	Carbon-nitrogen hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	CN_hydrolase
k141_876_1	243277.VC_1636	3.4e-129	386.0	COG1061@1|root,COG1061@2|Bacteria,1MV9F@1224|Proteobacteria,1RNAN@1236|Gammaproteobacteria,1XV70@135623|Vibrionales	135623|Vibrionales	KL	COG1061 DNA or RNA helicases of superfamily II	yejH	-	-	ko:K19789	-	-	-	-	ko00000,ko03400	-	-	-	Helicase_C,ResIII
k141_876_2	345073.VC395_1752	8.38e-126	363.0	COG1187@1|root,COG1187@2|Bacteria,1MU6M@1224|Proteobacteria,1RQA9@1236|Gammaproteobacteria,1XTEX@135623|Vibrionales	135623|Vibrionales	J	Belongs to the pseudouridine synthase RsuA family	rsuA	GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	5.4.99.19	ko:K06183	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
k141_876_3	223926.28806205	1.77e-102	303.0	2EAF8@1|root,334IN@2|Bacteria,1ND4K@1224|Proteobacteria,1SBS5@1236|Gammaproteobacteria,1XTF7@135623|Vibrionales	135623|Vibrionales	S	Protein of unknown function (DUF2913)	VP1217	-	-	-	-	-	-	-	-	-	-	-	DUF2913
k141_4305_9	675815.VOA_002085	1.8e-100	297.0	COG1842@1|root,COG1842@2|Bacteria,1NC7S@1224|Proteobacteria,1RS0G@1236|Gammaproteobacteria,1XUJH@135623|Vibrionales	135623|Vibrionales	KT	COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription	pspA	-	-	ko:K03969	-	-	-	-	ko00000	-	-	-	PspA_IM30
k141_4305_10	675817.VDA_001812	3.06e-143	415.0	COG3829@1|root,COG3829@2|Bacteria,1QUPP@1224|Proteobacteria,1T3RG@1236|Gammaproteobacteria,1Y362@135623|Vibrionales	135623|Vibrionales	K	Bacterial regulatory protein, Fis family	pspF	-	-	ko:K03974	-	-	-	-	ko00000,ko03000	-	-	-	HTH_8,Sigma54_activat
k141_4305_11	945550.VISI1226_19881	5.81e-219	623.0	COG4166@1|root,COG4166@2|Bacteria,1P91R@1224|Proteobacteria,1T1RS@1236|Gammaproteobacteria,1XUUH@135623|Vibrionales	135623|Vibrionales	E	COG4166 ABC-type oligopeptide transport system, periplasmic component	sapA	-	-	ko:K19226	ko01503,ko02010,map01503,map02010	M00739	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.5	-	-	SBP_bac_5
k141_4305_12	1219065.VPR01S_24_00030	1.1e-159	455.0	COG4168@1|root,COG4168@2|Bacteria,1QUAU@1224|Proteobacteria,1T1RR@1236|Gammaproteobacteria,1XTN1@135623|Vibrionales	135623|Vibrionales	P	peptide transport system, permease	sapB	-	-	ko:K19227	ko01503,ko02010,map01503,map02010	M00739	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.5	-	-	BPD_transp_1
k141_4305_13	55601.VANGNB10_cI1123c	1.08e-142	410.0	COG4171@1|root,COG4171@2|Bacteria,1QUAT@1224|Proteobacteria,1T1RQ@1236|Gammaproteobacteria,1XSV7@135623|Vibrionales	135623|Vibrionales	V	COG4171 ABC-type antimicrobial peptide transport system, permease component	sapC	-	-	ko:K19228	ko01503,ko02010,map01503,map02010	M00739	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.5	-	-	BPD_transp_1,OppC_N
k141_4305_16	1116375.VEJY3_12460	2.5e-56	196.0	COG0671@1|root,COG0671@2|Bacteria,1RF6B@1224|Proteobacteria,1SC5U@1236|Gammaproteobacteria,1XVV7@135623|Vibrionales	135623|Vibrionales	I	COG0671 Membrane-associated phospholipid phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	PAP2_3
k141_4305_18	1219065.VPR01S_08_00990	0.0	954.0	COG0322@1|root,COG0322@2|Bacteria,1MV38@1224|Proteobacteria,1RNGV@1236|Gammaproteobacteria,1XT19@135623|Vibrionales	135623|Vibrionales	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009380,GO:0009381,GO:0009987,GO:0016787,GO:0016788,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1902494,GO:1905347,GO:1905348,GO:1990391	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH,HHH_5,UVR,UvrC_HhH_N
k141_4305_20	796620.VIBC2010_15259	6.41e-64	204.0	COG1708@1|root,COG1708@2|Bacteria,1RID1@1224|Proteobacteria,1S9KW@1236|Gammaproteobacteria,1XTT0@135623|Vibrionales	135623|Vibrionales	S	nucleotidyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_2
k141_2589_2	1051646.VITU9109_15643	9.28e-106	312.0	COG3672@1|root,COG3672@2|Bacteria,1RDQS@1224|Proteobacteria,1S3Y1@1236|Gammaproteobacteria,1XST8@135623|Vibrionales	135623|Vibrionales	S	Periplasmic Protein	lapF	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C93
k141_2589_3	945550.VISI1226_12996	4.83e-181	517.0	COG0845@1|root,COG0845@2|Bacteria,1MUI8@1224|Proteobacteria,1RNK4@1236|Gammaproteobacteria,1XSCT@135623|Vibrionales	135623|Vibrionales	M	COG0845 Membrane-fusion protein	lapC	-	-	ko:K12542	-	M00330	-	-	ko00000,ko00002,ko02000,ko02044	3.A.1.109.4,8.A.1	-	-	Biotin_lipoyl_2,HlyD,HlyD_3,OEP
k141_2591_1	224911.27354572	4.35e-28	119.0	COG2274@1|root,COG2274@2|Bacteria,1R2T0@1224|Proteobacteria,2USBQ@28211|Alphaproteobacteria,3JRFR@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	V	ABC transporter	-	-	-	ko:K06147,ko:K11004	ko02010,ko03070,ko05133,map02010,map03070,map05133	M00325,M00575	-	-	ko00000,ko00001,ko00002,ko02000,ko02044	3.A.1.106,3.A.1.109,3.A.1.109.1,3.A.1.109.2,3.A.1.21	-	-	ABC_membrane,ABC_tran,Peptidase_C39
k141_3276_1	443143.GM18_3403	7.35e-42	145.0	COG3932@1|root,COG3932@2|Bacteria,1N0FN@1224|Proteobacteria	1224|Proteobacteria	S	ABC-type transport system, permease components	-	-	-	-	-	-	-	-	-	-	-	-	ExoD
k141_1303_1	1304885.AUEY01000079_gene1030	1.9e-247	776.0	COG0304@1|root,COG1028@1|root,COG2070@1|root,COG3321@1|root,COG0304@2|Bacteria,COG1028@2|Bacteria,COG2070@2|Bacteria,COG3321@2|Bacteria,1R89Z@1224|Proteobacteria,42NGA@68525|delta/epsilon subdivisions,2WJK3@28221|Deltaproteobacteria,2MIK4@213118|Desulfobacterales	28221|Deltaproteobacteria	IQ	Beta-ketoacyl synthase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_1,KAsynt_C_assoc,KR,Ketoacyl-synt_C,NMO,PP-binding,PS-DH,ketoacyl-synt
k141_4999_1	1191299.AJYX01000066_gene4005	1.66e-33	120.0	COG0705@1|root,COG0705@2|Bacteria,1N8NS@1224|Proteobacteria,1SD4M@1236|Gammaproteobacteria,1XXEV@135623|Vibrionales	135623|Vibrionales	S	membrane protein (homolog of Drosophila rhomboid)	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
k141_4999_2	1191299.AJYX01000066_gene4006	8.94e-96	284.0	COG3148@1|root,COG3148@2|Bacteria,1MZCN@1224|Proteobacteria,1S977@1236|Gammaproteobacteria,1XUVF@135623|Vibrionales	135623|Vibrionales	S	DTW	-	-	-	-	-	-	-	-	-	-	-	-	DTW
k141_4999_3	1348635.BBJY01000007_gene80	5.49e-234	654.0	COG0232@1|root,COG0232@2|Bacteria,1MVQ2@1224|Proteobacteria,1RPVJ@1236|Gammaproteobacteria,1XTWV@135623|Vibrionales	135623|Vibrionales	F	Belongs to the dGTPase family. Type 2 subfamily	dgt	GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0015949,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576	3.1.5.1	ko:K01129	ko00230,map00230	-	R01856	RC00017	ko00000,ko00001,ko01000	-	-	-	HD,HD_assoc
k141_1560_1	29495.EA26_06035	5.2e-213	611.0	COG2838@1|root,COG2838@2|Bacteria,1MV6Q@1224|Proteobacteria,1RPG4@1236|Gammaproteobacteria,1XUW0@135623|Vibrionales	135623|Vibrionales	C	Isocitrate dehydrogenase	icd	-	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	IDH
k141_1560_2	1348635.BBJY01000004_gene3013	9.39e-46	147.0	COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,1SCA7@1236|Gammaproteobacteria,1XYAU@135623|Vibrionales	135623|Vibrionales	K	COG1278 Cold shock proteins	cspD	GO:0006355,GO:0006950,GO:0008150,GO:0009266,GO:0009409,GO:0009628,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
k141_1560_3	945543.VIBR0546_19574	4.55e-59	183.0	COG2127@1|root,COG2127@2|Bacteria,1MZU8@1224|Proteobacteria,1S8Z7@1236|Gammaproteobacteria,1XXDA@135623|Vibrionales	135623|Vibrionales	S	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation	clpS	-	-	ko:K06891	-	-	-	-	ko00000	-	-	-	ClpS
k141_1560_4	223926.28806001	0.0	1280.0	COG0542@1|root,COG0542@2|Bacteria,1MV8B@1224|Proteobacteria,1RMH3@1236|Gammaproteobacteria,1XSKE@135623|Vibrionales	135623|Vibrionales	O	Belongs to the ClpA ClpB family	clpA	-	-	ko:K03694	-	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
k141_1560_6	672.VV93_v1c20300	1.37e-108	318.0	COG2935@1|root,COG2935@2|Bacteria,1MW62@1224|Proteobacteria,1RYD7@1236|Gammaproteobacteria,1XSUB@135623|Vibrionales	135623|Vibrionales	O	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate	ate	GO:0003674,GO:0003824,GO:0004057,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006508,GO:0006511,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016598,GO:0016740,GO:0016746,GO:0016755,GO:0019538,GO:0019941,GO:0030163,GO:0036211,GO:0043170,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044464,GO:0051603,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575	2.3.2.29	ko:K21420	-	-	R11547,R11548	RC00064	ko00000,ko01000	-	-	-	ATE_C,ATE_N
k141_1560_7	675816.VIA_002472	1.01e-124	360.0	COG2360@1|root,COG2360@2|Bacteria,1R9W8@1224|Proteobacteria,1S1ZB@1236|Gammaproteobacteria,1XU2W@135623|Vibrionales	135623|Vibrionales	O	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine	aat	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008914,GO:0016740,GO:0016746,GO:0016755,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0071704,GO:0140096,GO:1901564	2.3.2.6	ko:K00684	-	-	R03813,R11443,R11444	RC00055,RC00064	ko00000,ko01000	-	-	-	Leu_Phe_trans
k141_1560_8	672.VV93_v1c20280	1.23e-36	130.0	COG3133@1|root,COG3133@2|Bacteria,1RIY9@1224|Proteobacteria,1S819@1236|Gammaproteobacteria,1XX6N@135623|Vibrionales	135623|Vibrionales	M	Glycine zipper 2TM domain	slyB	-	-	ko:K06077	-	-	-	-	ko00000	-	-	-	Rick_17kDa_Anti
k141_1560_9	1348635.BBJY01000004_gene3029	5.59e-257	711.0	COG0128@1|root,COG0128@2|Bacteria,1MWMK@1224|Proteobacteria,1RQ8U@1236|Gammaproteobacteria,1XSTG@135623|Vibrionales	135623|Vibrionales	E	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	aroA	GO:0003674,GO:0003824,GO:0003866,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	EPSP_synthase
k141_1560_10	1051646.VITU9109_00280	3.46e-41	136.0	2CK10@1|root,32SBA@2|Bacteria,1N8PV@1224|Proteobacteria,1S938@1236|Gammaproteobacteria,1XYF4@135623|Vibrionales	135623|Vibrionales	S	Protein of unknown function (DUF2498)	STY1335	-	-	-	-	-	-	-	-	-	-	-	DUF2498
k141_1560_11	1280001.BAOA01000060_gene2339	0.0	1508.0	COG0550@1|root,COG0550@2|Bacteria,1MUFZ@1224|Proteobacteria,1RNZ2@1236|Gammaproteobacteria,1XSSB@135623|Vibrionales	135623|Vibrionales	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	GO:0003674,GO:0003824,GO:0003916,GO:0003917,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016853,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topo_Zn_Ribbon,Topoisom_bac,Toprim,zf-C4_Topoisom
k141_1560_12	55601.VANGNB10_cI1086	1.91e-251	694.0	COG0448@1|root,COG0448@2|Bacteria,1MVTC@1224|Proteobacteria,1RP04@1236|Gammaproteobacteria,1XTGB@135623|Vibrionales	135623|Vibrionales	H	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans	glgC	GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0008878,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016772,GO:0016779,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0055114,GO:0070566,GO:0071704,GO:1901576	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
k141_1560_13	1348635.BBJY01000004_gene3034	7.55e-260	722.0	COG0297@1|root,COG0297@2|Bacteria,1MUGM@1224|Proteobacteria,1RNMP@1236|Gammaproteobacteria,1XSTA@135623|Vibrionales	135623|Vibrionales	F	Synthesizes alpha-1,4-glucan chains using ADP-glucose	glgA	GO:0000271,GO:0003674,GO:0003824,GO:0004373,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0008194,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0035251,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046527,GO:0055114,GO:0071704,GO:1901576	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Glyco_transf_5,Glycos_transf_1
k141_1560_14	675813.VIB_001100	2.33e-142	407.0	COG0596@1|root,COG0596@2|Bacteria,1R53J@1224|Proteobacteria,1RXY0@1236|Gammaproteobacteria,1XV80@135623|Vibrionales	135623|Vibrionales	S	hydrolases or acyltransferases (alpha beta hydrolase superfamily)	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
k141_1560_15	55601.VANGNB10_cI1091c	2.79e-80	244.0	COG3070@1|root,COG3070@2|Bacteria,1RDWD@1224|Proteobacteria,1S496@1236|Gammaproteobacteria,1XUVA@135623|Vibrionales	135623|Vibrionales	K	COG3070 Regulator of competence-specific genes	tfoX	GO:0006810,GO:0007154,GO:0008150,GO:0009290,GO:0009292,GO:0009294,GO:0009605,GO:0009987,GO:0009991,GO:0015931,GO:0030420,GO:0031668,GO:0044764,GO:0050657,GO:0050896,GO:0051027,GO:0051179,GO:0051234,GO:0051704,GO:0051716,GO:0071496,GO:0071702,GO:0071705,GO:0098657	-	ko:K07343	-	-	-	-	ko00000	-	-	-	TfoX_C,TfoX_N
k141_1560_16	243277.VC_1721	4.59e-210	584.0	COG1609@1|root,COG1609@2|Bacteria,1MVUR@1224|Proteobacteria,1RN2K@1236|Gammaproteobacteria,1XU47@135623|Vibrionales	135623|Vibrionales	K	Is the main repressor of the genes involved in the de novo synthesis of purine nucleotides, regulating purB, purC, purEK, purF, purHD, purL, purMN and guaBA expression. PurR is allosterically activated to bind its cognate DNA by binding the purine corepressors, hypoxanthine or guanine, thereby effecting transcription repression	purR	GO:0003674,GO:0003700,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2001141	-	ko:K03604	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
k141_1560_17	1187848.AJYQ01000066_gene3579	2.68e-127	369.0	COG1434@1|root,COG1434@2|Bacteria,1MVW8@1224|Proteobacteria,1RNZC@1236|Gammaproteobacteria,1XUG3@135623|Vibrionales	135623|Vibrionales	S	DUF218 domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF218
k141_1560_18	945550.VISI1226_09249	9.22e-146	415.0	COG2227@1|root,COG2227@2|Bacteria,1MY0S@1224|Proteobacteria,1RP69@1236|Gammaproteobacteria,1XSUE@135623|Vibrionales	135623|Vibrionales	J	Catalyzes the methylation of 5-carboxymethoxyuridine (cmo5U) to form 5-methoxycarbonylmethoxyuridine (mcmo5U) at position 34 in tRNAs	cmoM	-	-	ko:K06219	-	-	-	-	ko00000	-	-	-	Methyltransf_11,Methyltransf_31
k141_1560_19	29495.EA26_06145	1.01e-236	660.0	COG3006@1|root,COG3006@2|Bacteria,1N0D6@1224|Proteobacteria,1RN7P@1236|Gammaproteobacteria,1XSU3@135623|Vibrionales	135623|Vibrionales	D	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity	mukF	-	-	ko:K03633	-	-	-	-	ko00000,ko03036	-	-	-	KicB,MukF_C,MukF_M
k141_1560_20	345073.VC395_1832	5.69e-123	356.0	COG3095@1|root,COG3095@2|Bacteria,1MXYN@1224|Proteobacteria,1RRBE@1236|Gammaproteobacteria,1XTJ6@135623|Vibrionales	135623|Vibrionales	D	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF	mukE	GO:0007059,GO:0008150,GO:0009987	-	ko:K03804	-	-	-	-	ko00000,ko03036	-	-	-	MukE
k141_1560_21	1219065.VPR01S_02_03210	0.0	1922.0	COG3096@1|root,COG3096@2|Bacteria,1MUWM@1224|Proteobacteria,1RPFF@1236|Gammaproteobacteria,1XUHB@135623|Vibrionales	135623|Vibrionales	D	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division	mukB	GO:0007059,GO:0008150,GO:0009987	-	ko:K03632	-	-	-	-	ko00000,ko03036	-	-	-	MukB,MukB_hinge,SbcCD_C
k141_1560_22	243277.VC_1160	1.8e-186	523.0	COG0189@1|root,COG0189@2|Bacteria,1MVDU@1224|Proteobacteria,1RR7D@1236|Gammaproteobacteria,1XV35@135623|Vibrionales	135623|Vibrionales	HJ	COG0189 Glutathione synthase Ribosomal protein S6 modification enzyme (glutaminyl transferase)	PA1766	-	-	-	-	-	-	-	-	-	-	-	ATPgrasp_ST
k141_1560_23	870967.VIS19158_20646	5.37e-263	732.0	COG1305@1|root,COG1305@2|Bacteria,1MVV3@1224|Proteobacteria,1RRIA@1236|Gammaproteobacteria,1XSMI@135623|Vibrionales	135623|Vibrionales	E	7 transmembrane helices usually fused to an inactive transglutaminase	-	-	-	-	-	-	-	-	-	-	-	-	7TM_transglut,Transglut_i_TM
k141_1560_24	1348635.BBJY01000004_gene3061	1.51e-84	259.0	COG4067@1|root,COG4067@2|Bacteria,1N0VV@1224|Proteobacteria,1SZUE@1236|Gammaproteobacteria,1XU7F@135623|Vibrionales	135623|Vibrionales	O	protein conserved in archaea	-	-	-	-	-	-	-	-	-	-	-	-	Zn_protease
k141_1560_25	1238450.VIBNISOn1_50028	8.59e-193	539.0	COG0500@1|root,COG0500@2|Bacteria,1MVSK@1224|Proteobacteria,1RMQY@1236|Gammaproteobacteria,1XSY3@135623|Vibrionales	135623|Vibrionales	J	Catalyzes carboxymethyl transfer from carboxy-S- adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs	cmoB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044464	-	ko:K15257	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_9
k141_1560_26	1219080.VEZ01S_08_00520	6.69e-138	394.0	COG4106@1|root,COG4106@2|Bacteria,1QTS9@1224|Proteobacteria,1T1FG@1236|Gammaproteobacteria,1XSJZ@135623|Vibrionales	135623|Vibrionales	H	Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM)	cmoA	-	-	ko:K15256	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_11,Methyltransf_25
k141_1560_27	945550.VISI1226_09199	0.0	1029.0	COG0173@1|root,COG0173@2|Bacteria,1MUXB@1224|Proteobacteria,1RNMI@1236|Gammaproteobacteria,1XSZA@135623|Vibrionales	135623|Vibrionales	J	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)	aspS	GO:0003674,GO:0003824,GO:0004812,GO:0004815,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006422,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
k141_1560_28	1187848.AJYQ01000066_gene3563	4.55e-96	284.0	COG1435@1|root,COG1435@2|Bacteria,1NJR4@1224|Proteobacteria,1RPCK@1236|Gammaproteobacteria,1XT1V@135623|Vibrionales	135623|Vibrionales	F	Thymidine kinase	tdk	GO:0003674,GO:0003824,GO:0004797,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006259,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009120,GO:0009123,GO:0009124,GO:0009157,GO:0009162,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019136,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046104,GO:0046125,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0090304,GO:0090407,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657	2.7.1.21	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01567,R02099,R08233	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	TK
k141_1560_30	1318628.MARLIPOL_02945	7.68e-59	202.0	COG5492@1|root,COG5492@2|Bacteria,1NVVT@1224|Proteobacteria,1SP61@1236|Gammaproteobacteria	1236|Gammaproteobacteria	N	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_1560_31	243277.VC_1696	5.1e-22	89.4	2E5ME@1|root,330CB@2|Bacteria,1N8G6@1224|Proteobacteria,1SC9I@1236|Gammaproteobacteria,1XYC2@135623|Vibrionales	135623|Vibrionales	S	Phosphate-starvation-inducible E	-	-	-	-	-	-	-	-	-	-	-	-	PsiE
k141_1560_33	243277.VC_1219	2.09e-218	604.0	COG0016@1|root,COG0016@2|Bacteria,1MVD7@1224|Proteobacteria,1RN22@1236|Gammaproteobacteria,1XTCW@135623|Vibrionales	135623|Vibrionales	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily	pheS	GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Phe_tRNA-synt_N,tRNA-synt_2d
k141_1560_34	1348635.BBJY01000017_gene4164	9.54e-109	335.0	COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria,1MWKS@1224|Proteobacteria,1RMIH@1236|Gammaproteobacteria,1XSJE@135623|Vibrionales	135623|Vibrionales	J	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily	pheT	GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
k141_908_1	1051646.VITU9109_18765	3.55e-110	350.0	COG2206@1|root,COG3437@1|root,COG2206@2|Bacteria,COG3437@2|Bacteria,1MV37@1224|Proteobacteria,1RM9C@1236|Gammaproteobacteria,1XSHM@135623|Vibrionales	135623|Vibrionales	KT	COG0840 Methyl-accepting chemotaxis protein	-	-	-	-	-	-	-	-	-	-	-	-	HD,HD_5,dCache_1
k141_908_2	55601.VANGNB10_cII0811c	5.13e-118	344.0	COG1387@1|root,COG1387@2|Bacteria,1MYXV@1224|Proteobacteria,1RRE9@1236|Gammaproteobacteria,1XTMG@135623|Vibrionales	135623|Vibrionales	E	Histidinol phosphatase and related hydrolases of the PHP family	-	GO:0001539,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006928,GO:0008150,GO:0008270,GO:0009987,GO:0016787,GO:0016788,GO:0040011,GO:0042578,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0048870,GO:0051179,GO:0051674,GO:0071973,GO:0071978,GO:0097588	-	ko:K04477	-	-	-	-	ko00000	-	-	-	PHP
k141_908_4	675813.VIB_002472	5.99e-158	450.0	COG0583@1|root,COG0583@2|Bacteria,1N4BZ@1224|Proteobacteria,1RRCD@1236|Gammaproteobacteria,1XTHR@135623|Vibrionales	135623|Vibrionales	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
k141_1304_1	1121405.dsmv_3659	1.84e-187	560.0	COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,42NCZ@68525|delta/epsilon subdivisions,2WK3X@28221|Deltaproteobacteria,2MI5E@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K07787	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4	-	iAF987.Gmet_1547	ACR_tran
k141_2907_4	400668.Mmwyl1_0637	6.37e-90	281.0	COG3180@1|root,COG3180@2|Bacteria,1MUFS@1224|Proteobacteria,1RPMJ@1236|Gammaproteobacteria,1XMPP@135619|Oceanospirillales	135619|Oceanospirillales	S	Transition state regulatory protein AbrB	-	-	-	ko:K07120	-	-	-	-	ko00000	-	-	-	AbrB
k141_2907_5	479433.Caci_1590	1.82e-43	150.0	COG1335@1|root,COG1335@2|Bacteria,2I9AW@201174|Actinobacteria	201174|Actinobacteria	Q	isochorismatase hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase
k141_2907_6	595494.Tola_0996	3.69e-146	421.0	COG0604@1|root,COG0604@2|Bacteria,1MV3W@1224|Proteobacteria,1RMHG@1236|Gammaproteobacteria,1Y50T@135624|Aeromonadales	135624|Aeromonadales	C	Zinc-binding dehydrogenase	-	-	-	ko:K19745	ko00640,ko01100,map00640,map01100	-	R00919	RC00095	ko00000,ko00001,ko01000	-	-	-	ADH_zinc_N
k141_1562_1	1390370.O203_04210	1.26e-42	162.0	COG2931@1|root,COG2982@1|root,COG3210@1|root,COG4625@1|root,COG2931@2|Bacteria,COG2982@2|Bacteria,COG3210@2|Bacteria,COG4625@2|Bacteria,1MU7T@1224|Proteobacteria,1S1HJ@1236|Gammaproteobacteria,1YFJH@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	MQU	Domain of unknown function (DUF4347)	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin,Cadherin_3,DUF4214,DUF4347,He_PIG,HemolysinCabind,PATR,VCBS
k141_2339_1	29495.EA26_07845	5.21e-30	110.0	298UB@1|root,2ZVYH@2|Bacteria,1NKPZ@1224|Proteobacteria,1SWFX@1236|Gammaproteobacteria,1Y2B3@135623|Vibrionales	135623|Vibrionales	S	Protein of unknown function (DUF3634)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3634
k141_2339_2	243277.VC_1481	1.14e-79	239.0	COG3120@1|root,COG3120@2|Bacteria,1RA57@1224|Proteobacteria,1S28S@1236|Gammaproteobacteria,1XWXZ@135623|Vibrionales	135623|Vibrionales	D	Required for spatial organization of the terminus region of the chromosome (Ter macrodomain) during the cell cycle. Prevents early segregation of duplicated Ter macrodomains during cell division. Binds specifically to matS, which is a 13 bp signature motif repeated within the Ter macrodomain	matP	-	-	ko:K09911	-	-	-	-	ko00000	-	-	-	MatP,MatP_C
k141_2339_3	55601.VANGNB10_cI1268c	5.49e-230	652.0	COG1067@1|root,COG1067@2|Bacteria,1MWGB@1224|Proteobacteria,1RMPC@1236|Gammaproteobacteria,1XVTZ@135623|Vibrionales	135623|Vibrionales	O	Belongs to the peptidase S16 family	-	-	-	ko:K04770	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	AAA_32,Lon_C
k141_2339_6	675813.VIB_001301	1.2e-64	219.0	2DMEK@1|root,32R04@2|Bacteria,1QYX8@1224|Proteobacteria,1T3WD@1236|Gammaproteobacteria,1Y37X@135623|Vibrionales	135623|Vibrionales	S	Protein of unknown function (DUF3466)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3466
k141_1042_44	1348635.BBJY01000006_gene374	5.77e-29	107.0	2BHGR@1|root,32BIW@2|Bacteria,1QKP8@1224|Proteobacteria,1TITJ@1236|Gammaproteobacteria,1XZMQ@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_1042_45	945550.VISI1226_23182	0.0	1001.0	COG0018@1|root,COG0018@2|Bacteria,1MU4J@1224|Proteobacteria,1RPRC@1236|Gammaproteobacteria,1XSVJ@135623|Vibrionales	135623|Vibrionales	J	Arginyl-tRNA synthetase	argS	GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
k141_719_2	1122599.AUGR01000013_gene702	4.22e-40	137.0	2DBTK@1|root,32TY3@2|Bacteria,1N17B@1224|Proteobacteria,1S95N@1236|Gammaproteobacteria,1XPUM@135619|Oceanospirillales	135619|Oceanospirillales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_369_1	1121396.KB893058_gene2569	3.58e-98	295.0	COG1120@1|root,COG1120@2|Bacteria,1MUNG@1224|Proteobacteria,42NRB@68525|delta/epsilon subdivisions,2WJHF@28221|Deltaproteobacteria,2MJI6@213118|Desulfobacterales	28221|Deltaproteobacteria	HP	ABC transporter	-	-	3.6.3.34	ko:K02013	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	ABC_tran
k141_1043_1	435590.BVU_0218	5.3e-06	54.7	COG4977@1|root,COG4977@2|Bacteria,4PKX4@976|Bacteroidetes,2FNFD@200643|Bacteroidia,4AKK1@815|Bacteroidaceae	976|Bacteroidetes	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18,HTH_AraC
k141_53_1	879212.DespoDRAFT_02362	8.99e-84	257.0	COG1360@1|root,COG1360@2|Bacteria,1MU4S@1224|Proteobacteria,42Q7D@68525|delta/epsilon subdivisions,2WKIT@28221|Deltaproteobacteria,2MJ0E@213118|Desulfobacterales	28221|Deltaproteobacteria	N	Membrane MotB of proton-channel complex MotA/MotB	motB	-	-	ko:K02557	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	MotB_plug,OmpA
k141_53_2	1121396.KB893112_gene1958	2.22e-119	348.0	COG1291@1|root,COG1291@2|Bacteria,1MXK3@1224|Proteobacteria,42PR1@68525|delta/epsilon subdivisions,2WIQ8@28221|Deltaproteobacteria,2MJ93@213118|Desulfobacterales	28221|Deltaproteobacteria	N	PFAM MotA TolQ ExbB proton channel	-	-	-	ko:K02556	ko02020,ko02030,ko02040,map02020,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	MotA_ExbB
k141_53_4	56780.SYN_01415	1.09e-52	174.0	COG1896@1|root,COG1896@2|Bacteria,1R71H@1224|Proteobacteria,42NGN@68525|delta/epsilon subdivisions,2WKMF@28221|Deltaproteobacteria,2MRJY@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	PFAM metal-dependent phosphohydrolase, HD sub domain	-	-	-	ko:K07023	-	-	-	-	ko00000	-	-	-	HD_3
k141_53_5	338963.Pcar_0409	1.26e-18	90.1	COG1652@1|root,COG1652@2|Bacteria,1MUBV@1224|Proteobacteria,42QS9@68525|delta/epsilon subdivisions,2WN3H@28221|Deltaproteobacteria,43SES@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Lysin motif	-	-	-	-	-	-	-	-	-	-	-	-	LysM
k141_1045_1	1304885.AUEY01000065_gene1280	8.71e-54	174.0	COG1272@1|root,COG1272@2|Bacteria,1PGRH@1224|Proteobacteria,42SPM@68525|delta/epsilon subdivisions,2WMYY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	TIGRFAM channel protein, hemolysin III family	-	-	-	ko:K11068	-	-	-	-	ko00000,ko02042	-	-	-	HlyIII
k141_2744_1	879212.DespoDRAFT_03651	7.39e-95	300.0	COG2301@1|root,COG2301@2|Bacteria,1NAM2@1224|Proteobacteria,42P8P@68525|delta/epsilon subdivisions,2WJIP@28221|Deltaproteobacteria,2MJ35@213118|Desulfobacterales	28221|Deltaproteobacteria	G	Belongs to the HpcH HpaI aldolase family	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_4114_1	933262.AXAM01000020_gene46	9.15e-52	186.0	COG1262@1|root,COG4249@1|root,COG1262@2|Bacteria,COG4249@2|Bacteria,1NQ5K@1224|Proteobacteria,42MAT@68525|delta/epsilon subdivisions,2WKY9@28221|Deltaproteobacteria,2MIBZ@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Caspase domain	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,PEGA,Peptidase_C14
k141_4114_2	477184.KYC_24182	5.63e-37	140.0	COG1262@1|root,COG1262@2|Bacteria,1NQ5K@1224|Proteobacteria,2VHHM@28216|Betaproteobacteria	28216|Betaproteobacteria	KLT	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
k141_393_1	1232437.KL662036_gene2744	5.68e-113	329.0	COG0491@1|root,COG0491@2|Bacteria,1MUT2@1224|Proteobacteria,42MVA@68525|delta/epsilon subdivisions,2WKBW@28221|Deltaproteobacteria,2MJ8X@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
k141_82_1	1348635.BBJY01000026_gene2303	0.0	956.0	COG0138@1|root,COG0138@2|Bacteria,1MUDQ@1224|Proteobacteria,1RMWS@1236|Gammaproteobacteria,1XTI6@135623|Vibrionales	135623|Vibrionales	F	bifunctional purine biosynthesis protein purh	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
k141_82_2	223926.28807924	9.52e-271	745.0	COG0151@1|root,COG0151@2|Bacteria,1MUAH@1224|Proteobacteria,1RNS4@1236|Gammaproteobacteria,1XT9Q@135623|Vibrionales	135623|Vibrionales	F	Belongs to the GARS family	purD	GO:0003674,GO:0003824,GO:0004637,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	GARS_A,GARS_C,GARS_N
k141_82_3	945543.VIBR0546_14717	2.02e-63	204.0	28HWS@1|root,2Z82N@2|Bacteria,1QFI0@1224|Proteobacteria,1RPY5@1236|Gammaproteobacteria,1XTX1@135623|Vibrionales	135623|Vibrionales	M	Protein of unknown function (DUF1481)	atpB	-	-	-	-	-	-	-	-	-	-	-	DUF1481
k141_3437_2	1280001.BAOA01000008_gene4100	1.46e-95	278.0	COG2983@1|root,COG2983@2|Bacteria,1RHMX@1224|Proteobacteria,1S5XU@1236|Gammaproteobacteria,1XWWH@135623|Vibrionales	135623|Vibrionales	S	Belongs to the UPF0260 family	VV2402	-	-	ko:K09160	-	-	-	-	ko00000	-	-	-	CxxCxxCC
k141_3437_3	375286.mma_2931	2.7e-30	112.0	COG0727@1|root,32S46@2|Bacteria,1MZCU@1224|Proteobacteria,2VU00@28216|Betaproteobacteria,474XI@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Putative zinc- or iron-chelating domain	-	-	-	ko:K06940	-	-	-	-	ko00000	-	-	-	CxxCxxCC
k141_3437_4	672.VV93_v1c21160	1.78e-135	384.0	COG0353@1|root,COG0353@2|Bacteria,1MV9Q@1224|Proteobacteria,1RN99@1236|Gammaproteobacteria,1XUCA@135623|Vibrionales	135623|Vibrionales	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecR,Toprim_4
k141_3437_5	243277.VC_1055	1.83e-64	197.0	COG0718@1|root,COG0718@2|Bacteria,1RGZD@1224|Proteobacteria,1S5WU@1236|Gammaproteobacteria,1XXBA@135623|Vibrionales	135623|Vibrionales	S	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection	ybaB	-	-	ko:K09747	-	-	-	-	ko00000	-	-	-	YbaB_DNA_bd
k141_3437_6	675814.VIC_001786	8.36e-47	168.0	COG2812@1|root,COG2812@2|Bacteria,1MVCK@1224|Proteobacteria,1RMIA@1236|Gammaproteobacteria,1XV9Y@135623|Vibrionales	135623|Vibrionales	H	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3,DNA_pol3_tau_4,DNA_pol3_tau_5
k141_2754_2	445973.CLOBAR_02747	2.77e-93	288.0	COG1466@1|root,COG1466@2|Bacteria,1TRM0@1239|Firmicutes,24ASN@186801|Clostridia,25QPQ@186804|Peptostreptococcaceae	186801|Clostridia	L	DNA polymerase III, delta' subunit	holA	-	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta
k141_2754_3	500633.CLOHIR_02037	1.84e-30	110.0	COG0268@1|root,COG0268@2|Bacteria,1VEGX@1239|Firmicutes,24QNX@186801|Clostridia,25RNU@186804|Peptostreptococcaceae	186801|Clostridia	J	Binds directly to 16S ribosomal RNA	rpsT	-	-	ko:K02968	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S20p
k141_2754_4	546269.HMPREF0389_00026	0.0	967.0	COG0481@1|root,COG0481@2|Bacteria,1TP0G@1239|Firmicutes,247V8@186801|Clostridia,25QKW@186804|Peptostreptococcaceae	186801|Clostridia	M	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C
k141_2754_5	332101.JIBU02000027_gene2781	1.42e-116	344.0	COG0730@1|root,COG0730@2|Bacteria	2|Bacteria	S	response to heat	XK27_00825	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
k141_2754_6	642492.Clole_2008	2.72e-40	154.0	2AM2W@1|root,31BWX@2|Bacteria,1V84G@1239|Firmicutes,24DXG@186801|Clostridia	186801|Clostridia	-	-	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	Glucosaminidase
k141_2754_7	1301100.HG529365_gene1420	3.32e-129	382.0	COG0635@1|root,COG0635@2|Bacteria,1TPES@1239|Firmicutes,247P8@186801|Clostridia,36DU5@31979|Clostridiaceae	186801|Clostridia	H	Involved in the biosynthesis of porphyrin-containing compound	hemN	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
k141_2754_8	1304284.L21TH_1370	7.76e-89	278.0	COG1420@1|root,COG1420@2|Bacteria,1TQP7@1239|Firmicutes,247K2@186801|Clostridia,36DW8@31979|Clostridiaceae	186801|Clostridia	K	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons	hrcA	-	-	ko:K03705	-	-	-	-	ko00000,ko03000	-	-	-	HrcA,HrcA_DNA-bdg
k141_2754_9	1121289.JHVL01000002_gene2356	3.07e-43	150.0	COG0576@1|root,COG0576@2|Bacteria,1V6G2@1239|Firmicutes,24MQK@186801|Clostridia,36IQB@31979|Clostridiaceae	186801|Clostridia	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	-	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
k141_2754_10	1511.CLOST_1793	0.0	894.0	COG0443@1|root,COG0443@2|Bacteria,1TP1J@1239|Firmicutes,248QV@186801|Clostridia,25QS1@186804|Peptostreptococcaceae	186801|Clostridia	O	MreB/Mbl protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
k141_2754_11	1121324.CLIT_11c00880	2.6e-147	429.0	COG0484@1|root,COG0484@2|Bacteria,1TP00@1239|Firmicutes,248EM@186801|Clostridia,25QX8@186804|Peptostreptococcaceae	186801|Clostridia	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686,ko:K05516	-	-	-	-	ko00000,ko03029,ko03036,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
k141_2754_12	1121324.CLIT_11c00890	9.15e-137	398.0	COG2264@1|root,COG2264@2|Bacteria,1TPKI@1239|Firmicutes,247VY@186801|Clostridia,25R0W@186804|Peptostreptococcaceae	186801|Clostridia	J	Methylates ribosomal protein L11	prmA	-	-	ko:K02687	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PrmA
k141_2754_13	350688.Clos_1236	6.44e-66	212.0	COG1385@1|root,COG1385@2|Bacteria,1V1CT@1239|Firmicutes,249VK@186801|Clostridia,36DGZ@31979|Clostridiaceae	186801|Clostridia	J	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit	rsmE	-	2.1.1.193	ko:K09761	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_RNA
k141_2754_14	1391646.AVSU01000026_gene2375	4.59e-172	497.0	COG0621@1|root,COG0621@2|Bacteria,1TPBR@1239|Firmicutes,247IX@186801|Clostridia,25QMB@186804|Peptostreptococcaceae	186801|Clostridia	J	tRNA methylthiotransferase	yqeV	-	2.8.4.5	ko:K18707	-	-	R10649	RC00003,RC03221	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
k141_2754_15	1230342.CTM_01275	1.02e-54	173.0	COG0537@1|root,COG0537@2|Bacteria,1V9ZJ@1239|Firmicutes,24JCW@186801|Clostridia,36JIP@31979|Clostridiaceae	186801|Clostridia	FG	Hit family	hinT	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	HIT
k141_2754_16	1286171.EAL2_c14360	8.78e-23	88.6	COG0828@1|root,COG0828@2|Bacteria,1VEHU@1239|Firmicutes,24QP9@186801|Clostridia,25XHW@186806|Eubacteriaceae	186801|Clostridia	J	Belongs to the bacterial ribosomal protein bS21 family	rpsU	-	-	ko:K02970	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S21
k141_2754_17	1035196.HMPREF9998_00498	2.38e-50	164.0	COG1610@1|root,COG1610@2|Bacteria,1V6F2@1239|Firmicutes,24JB0@186801|Clostridia,25RGV@186804|Peptostreptococcaceae	186801|Clostridia	S	Yqey-like protein	yqeY	-	-	ko:K09117	-	-	-	-	ko00000	-	-	-	YqeY
k141_2754_18	1286171.EAL2_c14340	1.11e-96	303.0	COG1030@1|root,COG1030@2|Bacteria,1TR54@1239|Firmicutes,247N5@186801|Clostridia	186801|Clostridia	O	Membrane-bound serine protease (ClpP class)	yqeZ	-	-	ko:K07403	-	-	-	-	ko00000	-	-	-	CLP_protease,NfeD,SDH_sah
k141_2754_19	908338.HMPREF9286_0625	2.78e-142	412.0	COG4864@1|root,COG4864@2|Bacteria,1TPTD@1239|Firmicutes,24APU@186801|Clostridia,22G2G@1570339|Peptoniphilaceae	186801|Clostridia	S	UPF0365 protein	-	-	-	-	-	-	-	-	-	-	-	-	YdfA_immunity
k141_2396_1	1304885.AUEY01000009_gene1942	7.7e-153	457.0	COG0427@1|root,COG0427@2|Bacteria,1Q8ZS@1224|Proteobacteria,42NSQ@68525|delta/epsilon subdivisions,2WK0D@28221|Deltaproteobacteria,2MJ5K@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Acetyl-CoA hydrolase/transferase C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AcetylCoA_hyd_C
k141_2396_2	644282.Deba_3272	1.74e-132	392.0	COG0427@1|root,COG0427@2|Bacteria,1MUGE@1224|Proteobacteria,42MHC@68525|delta/epsilon subdivisions,2WINZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	acetyl-CoA hydrolase transferase	-	-	-	-	-	-	-	-	-	-	-	iAF987.Gmet_3304	AcetylCoA_hyd_C,AcetylCoA_hydro,Acetyltransf_1
k141_3438_1	1408473.JHXO01000005_gene1849	1.82e-25	102.0	COG2230@1|root,COG2230@2|Bacteria,4PMJ3@976|Bacteroidetes,2G0CV@200643|Bacteroidia	976|Bacteroidetes	M	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_12,Methyltransf_23,Methyltransf_25,Methyltransf_31
k141_3438_2	1265505.ATUG01000001_gene3211	6.65e-11	59.3	2EACD@1|root,334GB@2|Bacteria,1NETT@1224|Proteobacteria,42V8Z@68525|delta/epsilon subdivisions,2WRR6@28221|Deltaproteobacteria,2MKWJ@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	3.6.1.1	ko:K01507	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	-
k141_3767_2	675816.VIA_000647	1.65e-37	127.0	COG0425@1|root,COG0425@2|Bacteria,1MZA5@1224|Proteobacteria,1S8TC@1236|Gammaproteobacteria,1XYAC@135623|Vibrionales	135623|Vibrionales	O	Sulfur carrier protein which probably makes part of a sulfur-relay system	tusA	GO:0008150,GO:0009987,GO:0019725,GO:0042592,GO:0048878,GO:0055082,GO:0065007,GO:0065008	-	ko:K04085	ko04122,map04122	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	TusA
k141_3767_3	870967.VIS19158_22257	1.93e-35	122.0	2AWHF@1|root,31NDZ@2|Bacteria,1QK51@1224|Proteobacteria,1TI85@1236|Gammaproteobacteria,1XYM6@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_3767_4	29495.EA26_00605	1.26e-95	283.0	COG2119@1|root,COG2119@2|Bacteria,1RDDV@1224|Proteobacteria,1S3QT@1236|Gammaproteobacteria,1XSNJ@135623|Vibrionales	135623|Vibrionales	S	Uncharacterized protein family UPF0016	-	-	-	-	-	-	-	-	-	-	-	-	UPF0016
k141_3767_6	29495.EA26_00615	0.0	1153.0	COG0751@1|root,COG0751@2|Bacteria,1MV2F@1224|Proteobacteria,1RNR3@1236|Gammaproteobacteria,1XT5T@135623|Vibrionales	135623|Vibrionales	J	Glycyl-tRNA synthetase beta subunit	glyS	GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006426,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.14	ko:K01879	ko00970,map00970	M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_1,tRNA_synt_2f
k141_3767_7	1280001.BAOA01000148_gene2538	1.3e-255	706.0	COG3977@1|root,COG3977@2|Bacteria,1MVRW@1224|Proteobacteria,1RNK1@1236|Gammaproteobacteria,1XUEC@135623|Vibrionales	135623|Vibrionales	E	Valine--pyruvate aminotransferase	avtA	-	2.6.1.66	ko:K00835	ko00290,ko01100,ko01110,ko01130,map00290,map01100,map01110,map01130	-	R01215	RC00008,RC00036	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
k141_3767_8	243277.VC_0018	1.16e-80	241.0	COG0071@1|root,COG0071@2|Bacteria,1RH2X@1224|Proteobacteria,1S6WS@1236|Gammaproteobacteria,1XWXH@135623|Vibrionales	135623|Vibrionales	O	Belongs to the small heat shock protein (HSP20) family	ibpA	-	-	ko:K04080	-	-	-	-	ko00000,ko03110	-	-	-	HSP20
k141_3767_9	672.VV93_v1c00040	0.0	1362.0	COG0187@1|root,COG0187@2|Bacteria,1MVKT@1224|Proteobacteria,1RNB2@1236|Gammaproteobacteria,1XV37@135623|Vibrionales	135623|Vibrionales	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008150,GO:0008152,GO:0009295,GO:0009330,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017111,GO:0032991,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
k141_3767_10	55601.VANGNB10_cI0012	8.04e-223	618.0	COG1195@1|root,COG1195@2|Bacteria,1MX8N@1224|Proteobacteria,1RN5P@1236|Gammaproteobacteria,1XTHH@135623|Vibrionales	135623|Vibrionales	L	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP	recF	GO:0000731,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576	-	ko:K03629	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	SMC_N
k141_3767_11	55601.VANGNB10_cI0011	9.02e-205	573.0	COG0592@1|root,COG0592@2|Bacteria,1MVD9@1224|Proteobacteria,1RMNP@1236|Gammaproteobacteria,1XSM8@135623|Vibrionales	135623|Vibrionales	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	dnaN	GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032991,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
k141_3767_12	1280001.BAOA01000148_gene2543	5.95e-315	860.0	COG0593@1|root,COG0593@2|Bacteria,1MU5H@1224|Proteobacteria,1RNHP@1236|Gammaproteobacteria,1XT0F@135623|Vibrionales	135623|Vibrionales	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006275,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010556,GO:0016020,GO:0017076,GO:0019219,GO:0019222,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051052,GO:0051171,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363,GO:1901576,GO:1990837,GO:2000112	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
k141_3767_14	55601.VANGNB10_cI0006c	1.72e-20	81.6	COG0230@1|root,COG0230@2|Bacteria,1NGGS@1224|Proteobacteria,1SGDJ@1236|Gammaproteobacteria,1XYVN@135623|Vibrionales	135623|Vibrionales	J	Belongs to the bacterial ribosomal protein bL34 family	rpmH	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02914	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L34
k141_3767_15	1219065.VPR01S_22_00540	4.36e-62	191.0	COG0594@1|root,COG0594@2|Bacteria,1MZQE@1224|Proteobacteria,1S90M@1236|Gammaproteobacteria,1XXEW@135623|Vibrionales	135623|Vibrionales	J	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme	rnpA	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005655,GO:0005730,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0030677,GO:0030681,GO:0031974,GO:0031981,GO:0032991,GO:0034641,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044237,GO:0044238,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044452,GO:0044464,GO:0046483,GO:0070013,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1902555,GO:1905348,GO:1990904	3.1.26.5	ko:K03536	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Ribonuclease_P
k141_1401_2	76114.ebA6776	1.39e-28	107.0	COG1943@1|root,COG1943@2|Bacteria,1MX19@1224|Proteobacteria,2VTIQ@28216|Betaproteobacteria,2KYTR@206389|Rhodocyclales	206389|Rhodocyclales	L	Transposase IS200 like	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
k141_395_1	1307761.L21SP2_2126	3.28e-47	165.0	COG1196@1|root,COG1196@2|Bacteria	2|Bacteria	D	nuclear chromosome segregation	surE2	-	-	-	-	-	-	-	-	-	-	-	5_nucleotid,F5_F8_type_C,FIVAR,Flg_new,Glyco_hydro_20,Glyco_hydro_20b,Mob_Pre
k141_1402_1	1304885.AUEY01000082_gene2154	2.85e-122	371.0	COG0243@1|root,COG0243@2|Bacteria,1NR6J@1224|Proteobacteria,42NEV@68525|delta/epsilon subdivisions,2WJD0@28221|Deltaproteobacteria,2MHX6@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Molybdopterin oxidoreductase Fe4S4 domain	-	-	-	-	-	-	-	-	-	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
k141_396_1	1287276.X752_04380	1.54e-40	157.0	COG2110@1|root,COG2110@2|Bacteria,1MVYN@1224|Proteobacteria,2TSSS@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	phosphatase homologous to the C-terminal domain of histone macroH2A1	-	-	-	-	-	-	-	-	-	-	-	-	Macro
k141_2398_1	1461580.CCAS010000021_gene2309	1.1e-15	81.3	COG0747@1|root,COG0747@2|Bacteria,1TQ6S@1239|Firmicutes,4HAM7@91061|Bacilli,1ZBG8@1386|Bacillus	91061|Bacilli	E	COG0747 ABC-type dipeptide transport system, periplasmic component	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
k141_3440_1	747365.Thena_0826	2.18e-34	142.0	COG1337@1|root,COG1337@2|Bacteria,1V7HY@1239|Firmicutes,24DW1@186801|Clostridia,42FDF@68295|Thermoanaerobacterales	186801|Clostridia	L	RAMP superfamily	-	-	-	ko:K19134	-	-	-	-	ko00000,ko02048	-	-	-	RAMPs
k141_3098_1	1304885.AUEY01000002_gene333	4.39e-61	200.0	COG1237@1|root,COG1237@2|Bacteria,1NK2I@1224|Proteobacteria,42QRA@68525|delta/epsilon subdivisions,2WN1V@28221|Deltaproteobacteria,2MK22@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Metallo-beta-lactamase superfamily	-	-	2.5.1.105	ko:K06897	ko00790,map00790	-	R10339	RC00121	ko00000,ko00001,ko01000	-	-	-	Lactamase_B
k141_3098_2	1304885.AUEY01000002_gene321	1.78e-150	430.0	COG0685@1|root,COG0685@2|Bacteria,1MUC9@1224|Proteobacteria,42P5X@68525|delta/epsilon subdivisions,2WIQW@28221|Deltaproteobacteria,2MI3X@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Methylenetetrahydrofolate reductase	metF	-	1.5.1.20	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	M00377	R01224,R07168	RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR
k141_4449_1	55601.VANGNB10_cI1352c	9.78e-136	392.0	COG1737@1|root,COG1737@2|Bacteria,1MW2B@1224|Proteobacteria,1RNDZ@1236|Gammaproteobacteria,1XWEP@135623|Vibrionales	135623|Vibrionales	K	Helix-turn-helix domain, rpiR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_6,SIS
k141_4449_2	1280001.BAOA01000028_gene4956	3.97e-99	300.0	COG0697@1|root,COG0697@2|Bacteria,1R7CG@1224|Proteobacteria,1S0XU@1236|Gammaproteobacteria,1XVPK@135623|Vibrionales	135623|Vibrionales	EG	of the drug metabolite transporter (DMT) superfamily	-	-	-	-	-	-	-	-	-	-	-	-	EamA
k141_4449_3	743720.Psefu_0066	2.94e-68	211.0	COG0454@1|root,COG0456@2|Bacteria,1QU0C@1224|Proteobacteria,1S503@1236|Gammaproteobacteria,1YYUV@136845|Pseudomonas putida group	1236|Gammaproteobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
k141_4449_4	675816.VIA_000860	1.22e-186	531.0	COG0531@1|root,COG0531@2|Bacteria,1NCSX@1224|Proteobacteria,1RND7@1236|Gammaproteobacteria,1XUR8@135623|Vibrionales	135623|Vibrionales	E	COG0531 Amino acid transporters	-	-	-	ko:K16263	-	-	-	-	ko00000,ko02000	2.A.3.13	-	-	AA_permease_2
k141_4449_5	617140.AJZE01000093_gene2534	1.24e-45	153.0	COG1522@1|root,COG1522@2|Bacteria,1N2D6@1224|Proteobacteria,1S8VT@1236|Gammaproteobacteria,1XXCI@135623|Vibrionales	135623|Vibrionales	K	COG1522 Transcriptional regulators	VVA1240	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg,HTH_24,HTH_AsnC-type
k141_4449_6	55601.VANGNB10_cII0184	5.89e-95	282.0	COG1280@1|root,COG1280@2|Bacteria,1RDPB@1224|Proteobacteria,1S5JJ@1236|Gammaproteobacteria,1XTFX@135623|Vibrionales	135623|Vibrionales	E	threonine efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	LysE
k141_4449_7	672.VV93_v1c41560	4.87e-83	263.0	COG3203@1|root,COG3203@2|Bacteria,1Q1XX@1224|Proteobacteria,1RPIH@1236|Gammaproteobacteria,1XU0K@135623|Vibrionales	135623|Vibrionales	M	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane	VP1757	-	-	-	-	-	-	-	-	-	-	-	Porin_4
k141_4449_8	672.VV93_v1c41550	1.4e-27	106.0	2DYP2@1|root,34AHY@2|Bacteria,1QUHC@1224|Proteobacteria,1T1Z0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_786_4	945543.VIBR0546_05433	1.3e-117	368.0	COG3307@1|root,COG3307@2|Bacteria,1N5VZ@1224|Proteobacteria,1RMC4@1236|Gammaproteobacteria,1XUTS@135623|Vibrionales	135623|Vibrionales	M	COG3307 Lipid A core - O-antigen ligase and related enzymes	-	-	-	ko:K13009	-	-	-	-	ko00000,ko01000,ko01005	-	-	-	PglL_A,Wzy_C,Wzy_C_2
k141_786_5	675813.VIB_002136	0.0	1626.0	COG0178@1|root,COG0178@2|Bacteria,1MW0W@1224|Proteobacteria,1RMS9@1236|Gammaproteobacteria,1XSPJ@135623|Vibrionales	135623|Vibrionales	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009380,GO:0009381,GO:0009987,GO:0016787,GO:0016788,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1902494,GO:1905347,GO:1905348,GO:1990391	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
k141_786_7	345073.VC395_0440	3.96e-62	199.0	COG2197@1|root,COG2197@2|Bacteria,1R531@1224|Proteobacteria,1S18M@1236|Gammaproteobacteria,1XVDS@135623|Vibrionales	135623|Vibrionales	K	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	-	-	-	ko:K04333	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000	-	-	-	GerE
k141_786_9	1348635.BBJY01000021_gene2869	9.11e-310	863.0	COG2199@1|root,COG2200@1|root,COG2199@2|Bacteria,COG2200@2|Bacteria,1MUQV@1224|Proteobacteria,1RN0Q@1236|Gammaproteobacteria,1XSFU@135623|Vibrionales	135623|Vibrionales	T	COG2199 FOG GGDEF domain	csrD	-	-	ko:K18765	-	-	-	-	ko00000,ko03019	-	-	-	EAL,GAPES4,GGDEF
k141_786_11	243277.VC_0416	1.36e-166	471.0	COG1792@1|root,COG1792@2|Bacteria,1N8ZS@1224|Proteobacteria,1RMK4@1236|Gammaproteobacteria,1XSEQ@135623|Vibrionales	135623|Vibrionales	M	Involved in formation and maintenance of cell shape	mreC	-	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
k141_786_12	1348635.BBJY01000021_gene2851	7.4e-87	258.0	COG2891@1|root,COG2891@2|Bacteria,1RER7@1224|Proteobacteria,1S4DE@1236|Gammaproteobacteria,1XTT8@135623|Vibrionales	135623|Vibrionales	M	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins	mreD	-	-	ko:K03571	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreD
k141_786_13	1348635.BBJY01000021_gene2850	3.03e-73	226.0	COG0424@1|root,COG0424@2|Bacteria,1RH6H@1224|Proteobacteria,1S41D@1236|Gammaproteobacteria,1XVZI@135623|Vibrionales	135623|Vibrionales	D	COG0424 Nucleotide-binding protein implicated in inhibition of septum formation	maf	-	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
k141_786_14	675813.VIB_002114	0.0	872.0	COG1530@1|root,COG1530@2|Bacteria,1MV65@1224|Proteobacteria,1RMIW@1236|Gammaproteobacteria,1XTMA@135623|Vibrionales	135623|Vibrionales	J	COG1530 Ribonucleases G and E	rng	-	-	ko:K08301	-	-	-	-	ko00000,ko01000,ko03009,ko03019	-	-	-	RNase_E_G,S1
k141_786_15	55601.VANGNB10_cI0297	0.0	1411.0	COG3164@1|root,COG3164@2|Bacteria,1MXWF@1224|Proteobacteria,1RNUK@1236|Gammaproteobacteria,1XTHT@135623|Vibrionales	135623|Vibrionales	S	Protein of unknown function	VV2929	-	-	-	-	-	-	-	-	-	-	-	AsmA_2,DUF3971
k141_786_16	243277.VC_0422	6.13e-291	801.0	COG0312@1|root,COG0312@2|Bacteria,1MUSK@1224|Proteobacteria,1RMA5@1236|Gammaproteobacteria,1XTGF@135623|Vibrionales	135623|Vibrionales	S	Zn-dependent proteases and their inactivated homologs	tldD	-	-	ko:K03568	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
k141_786_17	1280001.BAOA01000048_gene1874	1.12e-69	213.0	COG3076@1|root,COG3076@2|Bacteria,1RDKS@1224|Proteobacteria,1S4A6@1236|Gammaproteobacteria,1XWVQ@135623|Vibrionales	135623|Vibrionales	S	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome	rraB	-	-	ko:K09893	-	-	-	-	ko00000,ko03019	-	-	-	RraB
k141_786_18	377629.TERTU_2311	8.56e-230	663.0	COG5297@1|root,COG5297@2|Bacteria,1QZH1@1224|Proteobacteria	1224|Proteobacteria	G	Glycoside hydrolase family 44	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_44
k141_786_19	203122.Sde_0064	2.14e-115	352.0	COG2730@1|root,COG2730@2|Bacteria,1PSHN@1224|Proteobacteria,1S0KR@1236|Gammaproteobacteria,4666Z@72275|Alteromonadaceae	1236|Gammaproteobacteria	G	CBD_II	-	-	3.2.1.78	ko:K01218	ko00051,ko02024,map00051,map02024	-	R01332	RC00467	ko00000,ko00001,ko01000	-	GH26	-	CBM_10,CBM_2,Cellulase
k141_786_21	55601.VANGNB10_cI0305c	0.0	1286.0	COG4666@1|root,COG4666@2|Bacteria,1MUNB@1224|Proteobacteria,1RMH7@1236|Gammaproteobacteria,1XUHS@135623|Vibrionales	135623|Vibrionales	S	transport system, fused permease components	-	-	-	-	-	-	-	-	-	-	-	-	DUF3394,DctM
k141_786_22	1280001.BAOA01000021_gene813	2.5e-185	520.0	COG2358@1|root,COG2358@2|Bacteria,1MXW1@1224|Proteobacteria,1RQN1@1236|Gammaproteobacteria,1XU72@135623|Vibrionales	135623|Vibrionales	S	transport system periplasmic component	-	-	-	ko:K07080	-	-	-	-	ko00000	-	-	-	NMT1_3
k141_786_24	870967.VIS19158_04331	6.76e-152	435.0	COG0039@1|root,COG0039@2|Bacteria,1MV57@1224|Proteobacteria,1RMAX@1236|Gammaproteobacteria,1XSFW@135623|Vibrionales	135623|Vibrionales	C	Catalyzes the reversible oxidation of malate to oxaloacetate	mdh	GO:0003674,GO:0003824,GO:0004470,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016491,GO:0016614,GO:0016615,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350	1.1.1.37	ko:K00024	ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740	R00342,R07136	RC00031	ko00000,ko00001,ko00002,ko01000	-	-	-	Ldh_1_C,Ldh_1_N
k141_786_25	55601.VANGNB10_cI0310c	1.69e-176	498.0	COG0142@1|root,COG0142@2|Bacteria,1MUK6@1224|Proteobacteria,1RPR7@1236|Gammaproteobacteria,1XTYZ@135623|Vibrionales	135623|Vibrionales	H	Belongs to the FPP GGPP synthase family	ispB	-	2.5.1.90	ko:K02523	ko00900,ko01110,map00900,map01110	-	R09248	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	-	polyprenyl_synt
k141_786_29	945550.VISI1226_01960	2.06e-127	368.0	COG2966@1|root,COG2966@2|Bacteria,1NH2X@1224|Proteobacteria,1RN1Q@1236|Gammaproteobacteria,1XSCP@135623|Vibrionales	135623|Vibrionales	S	Putative threonine/serine exporter	yjjP	-	-	-	-	-	-	-	-	-	-	-	ThrE
k141_786_30	243277.VC_0439	3.53e-88	261.0	COG3610@1|root,COG3610@2|Bacteria,1RAWK@1224|Proteobacteria,1S2KX@1236|Gammaproteobacteria,1XX2R@135623|Vibrionales	135623|Vibrionales	S	Threonine/Serine exporter, ThrE	-	-	-	-	-	-	-	-	-	-	-	-	ThrE_2
k141_786_31	243277.VC_0440	9.31e-70	215.0	COG0262@1|root,COG0262@2|Bacteria,1RH0P@1224|Proteobacteria,1S5VH@1236|Gammaproteobacteria,1XX0F@135623|Vibrionales	135623|Vibrionales	H	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis	folA	-	1.5.1.3	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	M00126,M00840	R00936,R00937,R00939,R00940,R02235,R02236,R11765	RC00109,RC00110,RC00158	ko00000,ko00001,ko00002,ko01000	-	-	-	DHFR_1
k141_786_32	675814.VIC_000905	6.31e-143	409.0	COG0639@1|root,COG0639@2|Bacteria,1MV10@1224|Proteobacteria,1RPUJ@1236|Gammaproteobacteria,1XTGT@135623|Vibrionales	135623|Vibrionales	T	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP	apaH	GO:0003674,GO:0003824,GO:0004551,GO:0004721,GO:0006139,GO:0006464,GO:0006470,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008138,GO:0008150,GO:0008152,GO:0008796,GO:0008803,GO:0009987,GO:0015949,GO:0016311,GO:0016462,GO:0016787,GO:0016788,GO:0016791,GO:0016817,GO:0016818,GO:0019538,GO:0034641,GO:0036211,GO:0042578,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044281,GO:0046483,GO:0055086,GO:0071704,GO:0140096,GO:1901360,GO:1901564	3.6.1.41	ko:K01525	ko00230,map00230	-	R00125	RC00002	ko00000,ko00001,ko01000	-	-	-	Metallophos
k141_786_33	1348635.BBJY01000021_gene2829	1.67e-66	204.0	COG2967@1|root,COG2967@2|Bacteria,1MZ2Z@1224|Proteobacteria,1S8SE@1236|Gammaproteobacteria,1XXD5@135623|Vibrionales	135623|Vibrionales	P	protein affecting Mg2 Co2 transport	apaG	-	-	ko:K06195	-	-	-	-	ko00000	-	-	-	DUF525
k141_786_35	1238450.VIBNISOn1_1430055	2.26e-175	496.0	COG1995@1|root,COG1995@2|Bacteria,1MX5W@1224|Proteobacteria,1RNZV@1236|Gammaproteobacteria,1XT1M@135623|Vibrionales	135623|Vibrionales	H	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)	pdxA	GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	1.1.1.262	ko:K00097	ko00750,ko01100,map00750,map01100	M00124	R05681,R05837,R07406	RC00089,RC00675,RC01475	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxA
k141_786_36	243277.VC_0445	6.95e-199	563.0	COG0760@1|root,COG0760@2|Bacteria,1MVB3@1224|Proteobacteria,1RMWU@1236|Gammaproteobacteria,1XV5K@135623|Vibrionales	135623|Vibrionales	M	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation	surA	GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0006457,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:0140096,GO:1901564	5.2.1.8	ko:K03771	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_3,SurA_N
k141_786_37	701176.VIBRN418_11655	0.0	1076.0	COG1452@1|root,COG1452@2|Bacteria,1MUJC@1224|Proteobacteria,1RQEX@1236|Gammaproteobacteria,1XSAA@135623|Vibrionales	135623|Vibrionales	M	Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane	lptD	GO:0008150,GO:0009636,GO:0042221,GO:0050896	-	ko:K04744	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	OstA,OstA_C
k141_786_38	55601.VANGNB10_cI0323	1.44e-112	333.0	COG1076@1|root,COG1076@2|Bacteria,1N270@1224|Proteobacteria,1RP0P@1236|Gammaproteobacteria,1XSR9@135623|Vibrionales	135623|Vibrionales	O	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host	djlA	-	-	ko:K05801	-	-	-	-	ko00000,ko03110	-	-	-	DnaJ,TerB
k141_786_40	243277.VC_0450	4.16e-198	558.0	COG0741@1|root,COG0741@2|Bacteria,1MW2T@1224|Proteobacteria,1RM9N@1236|Gammaproteobacteria,1XU51@135623|Vibrionales	135623|Vibrionales	M	Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and or cell division	mltC	-	-	ko:K08306	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	DUF3393,SLT
k141_786_42	675806.VII_003264	5.44e-231	637.0	COG1194@1|root,COG1194@2|Bacteria,1MUD4@1224|Proteobacteria,1RMBT@1236|Gammaproteobacteria,1XTX3@135623|Vibrionales	1236|Gammaproteobacteria	L	COG1194 A G-specific DNA glycosylase	mutY	GO:0003674,GO:0003824,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360	-	ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD,NUDIX_4
k141_786_43	675816.VIA_000176	2.25e-153	432.0	COG0220@1|root,COG0220@2|Bacteria,1MUWJ@1224|Proteobacteria,1RMFG@1236|Gammaproteobacteria,1XUSW@135623|Vibrionales	135623|Vibrionales	J	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA	trmB	GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234	2.1.1.33	ko:K03439	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_4
k141_786_44	674977.VMC_12660	1.46e-219	612.0	COG0635@1|root,COG0635@2|Bacteria,1MU76@1224|Proteobacteria,1RN6I@1236|Gammaproteobacteria,1XTWK@135623|Vibrionales	135623|Vibrionales	H	Involved in the biosynthesis of porphyrin-containing compound	yggW	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
k141_786_46	1051646.VITU9109_25410	2.99e-43	142.0	COG1872@1|root,COG1872@2|Bacteria,1MZ4E@1224|Proteobacteria,1S9AB@1236|Gammaproteobacteria,1XXVE@135623|Vibrionales	135623|Vibrionales	S	Belongs to the UPF0235 family	yggU	-	-	ko:K09131	-	-	-	-	ko00000	-	-	-	DUF167
k141_786_47	1219072.VHA01S_055_00100	4.16e-82	248.0	COG0762@1|root,COG0762@2|Bacteria,1RCZV@1224|Proteobacteria,1S6DW@1236|Gammaproteobacteria,1XTKT@135623|Vibrionales	135623|Vibrionales	S	Integral membrane protein	yggT	-	-	ko:K02221	-	-	-	-	ko00000,ko02044	-	-	-	YGGT
k141_786_48	1454202.PPBDW_120011___1	9.41e-111	327.0	COG0345@1|root,COG0345@2|Bacteria,1R5J1@1224|Proteobacteria,1RNQK@1236|Gammaproteobacteria,1XSBY@135623|Vibrionales	135623|Vibrionales	E	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline	proC	-	1.5.1.2	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	M00015	R01248,R01251,R03291,R03293	RC00054,RC00083	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_oxidored,P5CR_dimer
k141_786_49	345073.VC395_0505	8.18e-117	340.0	COG0325@1|root,COG0325@2|Bacteria,1MWN7@1224|Proteobacteria,1RNPM@1236|Gammaproteobacteria,1XT7U@135623|Vibrionales	135623|Vibrionales	S	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis	yggS	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0008144,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363	-	ko:K06997	-	-	-	-	ko00000	-	-	-	Ala_racemase_N
k141_786_50	795666.MW7_2733	2.64e-114	342.0	COG2805@1|root,COG2805@2|Bacteria,1MU3J@1224|Proteobacteria,2VHHW@28216|Betaproteobacteria,1K3Q4@119060|Burkholderiaceae	28216|Betaproteobacteria	NU	twitching motility protein	pilT	-	-	ko:K02669,ko:K12203	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2,3.A.7.10.1,3.A.7.9.1	-	-	T2SSE
k141_786_52	243277.VC_0467	4.04e-106	309.0	COG1678@1|root,COG1678@2|Bacteria,1RCXM@1224|Proteobacteria,1S3YV@1236|Gammaproteobacteria,1XU0H@135623|Vibrionales	135623|Vibrionales	K	Belongs to the UPF0301 (AlgH) family	yqgE	-	-	ko:K07735	-	-	-	-	ko00000,ko03000	-	-	-	DUF179
k141_786_54	345073.VC395_0513	9.53e-141	401.0	COG1385@1|root,COG1385@2|Bacteria,1MXCU@1224|Proteobacteria,1RPBN@1236|Gammaproteobacteria,1XUB1@135623|Vibrionales	135623|Vibrionales	J	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit	rsmE	-	2.1.1.193	ko:K09761	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_RNA
k141_786_58	1348635.BBJY01000006_gene430	0.0	1172.0	COG0021@1|root,COG0021@2|Bacteria,1MUEY@1224|Proteobacteria,1RMWP@1236|Gammaproteobacteria,1XSX1@135623|Vibrionales	135623|Vibrionales	G	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate	tktA	GO:0003674,GO:0003824,GO:0004802,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009987,GO:0016740,GO:0016744,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
k141_786_59	55601.VANGNB10_cI0348	1.26e-199	558.0	COG0057@1|root,COG0057@2|Bacteria,1MU93@1224|Proteobacteria,1RMBM@1236|Gammaproteobacteria,1XUQJ@135623|Vibrionales	135623|Vibrionales	H	Catalyzes the NAD-dependent conversion of D-erythrose 4- phosphate to 4-phosphoerythronate	epd	GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0048001,GO:0055114	1.2.1.72	ko:K03472	ko00750,ko01100,map00750,map01100	M00124	R01825	RC00242	ko00000,ko00001,ko00002,ko01000	-	-	-	Gp_dh_C,Gp_dh_N
k141_786_61	29495.EA26_18690	2.13e-236	652.0	COG0191@1|root,COG0191@2|Bacteria,1MURX@1224|Proteobacteria,1RQUC@1236|Gammaproteobacteria,1XUCQ@135623|Vibrionales	135623|Vibrionales	G	COG0191 Fructose tagatose bisphosphate aldolase	fbaA	-	4.1.2.13	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167,M00344,M00345	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	F_bP_aldolase
k141_786_62	223926.28807608	8.33e-148	422.0	COG0668@1|root,COG0668@2|Bacteria,1N596@1224|Proteobacteria,1RQZP@1236|Gammaproteobacteria,1XU44@135623|Vibrionales	135623|Vibrionales	M	COG0668 Small-conductance mechanosensitive channel	mscS	-	-	ko:K03442	-	-	-	-	ko00000,ko02000	1.A.23.2	-	-	MS_channel,TM_helix
k141_786_63	1191299.AJYX01000052_gene1408	4.69e-146	428.0	COG0617@1|root,COG0617@2|Bacteria,1MU2X@1224|Proteobacteria,1RPFJ@1236|Gammaproteobacteria,1XT9B@135623|Vibrionales	135623|Vibrionales	F	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'- nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases	cca	GO:0003674,GO:0003824,GO:0004652,GO:0004810,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0070566,GO:0071704,GO:0090304,GO:1901360,GO:1990817	2.7.7.72	ko:K00974	ko03013,map03013	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016	-	-	-	HD,PolyA_pol,PolyA_pol_RNAbd
k141_786_64	1517681.HW45_01040	8.68e-94	279.0	COG3103@1|root,COG4991@2|Bacteria,1MX7M@1224|Proteobacteria,1RS74@1236|Gammaproteobacteria,1XUUZ@135623|Vibrionales	135623|Vibrionales	T	SH3 domain protein	htrG	-	-	ko:K07184	-	-	-	-	ko00000	-	-	-	SH3_3
k141_786_67	870967.VIS19158_22012	1.8e-258	721.0	COG3025@1|root,COG3025@2|Bacteria,1MY43@1224|Proteobacteria,1RMP4@1236|Gammaproteobacteria,1XSYB@135623|Vibrionales	135623|Vibrionales	S	CYTH	ygiF	-	3.6.1.25	ko:K18446	-	-	-	-	ko00000,ko01000	-	-	-	CHAD,CYTH
k141_786_68	870967.VIS19158_22022	7.19e-159	461.0	COG0840@1|root,COG0840@2|Bacteria,1R9QT@1224|Proteobacteria,1RRT3@1236|Gammaproteobacteria,1XT29@135623|Vibrionales	135623|Vibrionales	NT	methyl-accepting chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal
k141_786_69	55601.VANGNB10_cI2202c	0.0	1306.0	COG1391@1|root,COG1391@2|Bacteria,1MU4I@1224|Proteobacteria,1RP9N@1236|Gammaproteobacteria,1XSHU@135623|Vibrionales	135623|Vibrionales	H	Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell	glnE	GO:0000820,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006521,GO:0006541,GO:0006542,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008882,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0010565,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0019752,GO:0031323,GO:0033238,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050789,GO:0050794,GO:0051171,GO:0062012,GO:0065007,GO:0070566,GO:0071704,GO:0080090,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.7.42,2.7.7.89	ko:K00982	-	-	-	-	ko00000,ko01000	-	-	-	GlnD_UR_UTase,GlnE
k141_786_70	345073.VC395_2552	8.69e-300	823.0	COG0615@1|root,COG2870@1|root,COG0615@2|Bacteria,COG2870@2|Bacteria,1MV3Z@1224|Proteobacteria,1RMAJ@1236|Gammaproteobacteria,1XV30@135623|Vibrionales	135623|Vibrionales	H	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose	hldE	-	2.7.1.167,2.7.7.70	ko:K03272	ko00540,ko01100,map00540,map01100	M00064	R05644,R05646	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_like,PfkB
k141_786_71	55601.VANGNB10_cI2200	1.83e-200	568.0	COG1538@1|root,COG1538@2|Bacteria,1MWCJ@1224|Proteobacteria,1RQQV@1236|Gammaproteobacteria,1XT4C@135623|Vibrionales	135623|Vibrionales	MU	COG1538 Outer membrane protein	tolC	GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705	-	ko:K12340	ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133	M00325,M00326,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko02044	1.B.17,2.A.6.2	-	-	OEP
k141_786_72	223926.28805409	1.87e-95	284.0	COG0494@1|root,COG0494@2|Bacteria,1RDMW@1224|Proteobacteria,1RPZV@1236|Gammaproteobacteria,1XUUC@135623|Vibrionales	135623|Vibrionales	L	COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes	nudF	-	3.6.1.13	ko:K01515	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
k141_786_73	1219065.VPR01S_21_00560	1.99e-82	246.0	COG3151@1|root,COG3151@2|Bacteria,1RA4E@1224|Proteobacteria,1SA3I@1236|Gammaproteobacteria,1XXGE@135623|Vibrionales	135623|Vibrionales	S	protein conserved in bacteria	-	-	-	ko:K09920	-	-	-	-	ko00000	-	-	-	DUF1249
k141_786_74	675813.VIB_000334	1.01e-131	380.0	COG1409@1|root,COG1409@2|Bacteria,1MWKX@1224|Proteobacteria,1RPA7@1236|Gammaproteobacteria,1XTA7@135623|Vibrionales	135623|Vibrionales	S	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes	cpdA	-	3.1.4.53	ko:K03651	ko00230,ko02025,map00230,map02025	-	R00191	RC00296	ko00000,ko00001,ko01000	-	-	-	Metallophos
k141_786_75	1517681.HW45_02205	3.51e-64	202.0	COG3150@1|root,COG3150@2|Bacteria,1MVJF@1224|Proteobacteria,1S5WF@1236|Gammaproteobacteria,1XTCB@135623|Vibrionales	135623|Vibrionales	S	esterase	yqiA	-	-	ko:K07000	-	-	-	-	ko00000	-	-	-	UPF0227
k141_786_76	675814.VIC_000766	0.0	1157.0	COG0187@1|root,COG0187@2|Bacteria,1MVH1@1224|Proteobacteria,1RMCI@1236|Gammaproteobacteria,1XT02@135623|Vibrionales	135623|Vibrionales	L	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule	parE	-	-	ko:K02622	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
k141_786_77	1051646.VITU9109_06730	0.0	1312.0	COG0188@1|root,COG0188@2|Bacteria,1MURI@1224|Proteobacteria,1RMTC@1236|Gammaproteobacteria,1XSUU@135623|Vibrionales	135623|Vibrionales	L	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule	parC	-	-	ko:K02621	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
k141_786_78	1123487.KB892846_gene611	3.73e-41	141.0	COG2259@1|root,COG2259@2|Bacteria,1N1VA@1224|Proteobacteria,2VU9I@28216|Betaproteobacteria,2KZF6@206389|Rhodocyclales	206389|Rhodocyclales	S	DoxX	-	-	-	-	-	-	-	-	-	-	-	-	DoxX
k141_276_1	1265505.ATUG01000003_gene669	3.08e-158	461.0	COG0517@1|root,COG0618@1|root,COG0517@2|Bacteria,COG0618@2|Bacteria,1QW11@1224|Proteobacteria,42Q56@68525|delta/epsilon subdivisions,2WJXU@28221|Deltaproteobacteria,2MI8T@213118|Desulfobacterales	28221|Deltaproteobacteria	S	PFAM CBS domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CBS,DHH,DHHA1
k141_3594_1	675813.VIB_002207	1.65e-110	329.0	COG1454@1|root,COG1454@2|Bacteria,1MVPH@1224|Proteobacteria,1RMVU@1236|Gammaproteobacteria,1XVD1@135623|Vibrionales	135623|Vibrionales	C	Iron-containing alcohol dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Fe-ADH
k141_277_1	1177181.T9A_00414	2.88e-39	144.0	COG0743@1|root,COG0743@2|Bacteria,1MU4G@1224|Proteobacteria,1RNNW@1236|Gammaproteobacteria,1XIA5@135619|Oceanospirillales	135619|Oceanospirillales	I	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)	dxr	-	1.1.1.267	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05688	RC01452	ko00000,ko00001,ko00002,ko01000	-	-	-	DXPR_C,DXP_redisom_C,DXP_reductoisom
k141_277_2	96561.Dole_0481	1.14e-19	87.0	COG0750@1|root,COG0750@2|Bacteria,1MU91@1224|Proteobacteria,42NJ0@68525|delta/epsilon subdivisions,2WJ7A@28221|Deltaproteobacteria,2MIEV@213118|Desulfobacterales	28221|Deltaproteobacteria	M	SMART PDZ DHR GLGF domain protein	rseP	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_M50
k141_3595_1	1304885.AUEY01000047_gene74	4.05e-110	331.0	COG0773@1|root,COG0773@2|Bacteria,1MV68@1224|Proteobacteria,42MMP@68525|delta/epsilon subdivisions,2WK50@28221|Deltaproteobacteria,2MIR1@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Belongs to the MurCDEF family	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
k141_1530_1	1304885.AUEY01000012_gene1791	5.95e-72	228.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,42MK5@68525|delta/epsilon subdivisions,2WJ3Z@28221|Deltaproteobacteria,2MI0N@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM Acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
k141_1530_2	1304885.AUEY01000012_gene1790	1.78e-114	336.0	COG2086@1|root,COG2086@2|Bacteria,1MVH6@1224|Proteobacteria,42RMH@68525|delta/epsilon subdivisions,2WNKC@28221|Deltaproteobacteria,2MIZ2@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Electron transfer flavoprotein domain	etfB-3	-	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
k141_1530_3	1304885.AUEY01000012_gene1789	6.11e-145	419.0	COG2025@1|root,COG2025@2|Bacteria,1MUFI@1224|Proteobacteria,42M3T@68525|delta/epsilon subdivisions,2WIV8@28221|Deltaproteobacteria,2MIMG@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Electron transfer flavoprotein, alpha subunit	-	-	1.3.1.108	ko:K03522,ko:K22432	-	-	-	-	ko00000,ko01000,ko04147	-	-	-	ETF,ETF_alpha,Fer4
k141_1530_5	1121405.dsmv_2876	3.69e-87	275.0	COG2821@1|root,COG2821@2|Bacteria,1MXD4@1224|Proteobacteria,42P7C@68525|delta/epsilon subdivisions,2WKKF@28221|Deltaproteobacteria,2MIJE@213118|Desulfobacterales	28221|Deltaproteobacteria	M	PFAM MltA	-	-	-	ko:K08304	-	-	-	-	ko00000,ko01000,ko01011	-	GH102	-	3D,MltA
k141_2501_1	1232437.KL662005_gene4289	1.55e-57	193.0	COG0750@1|root,COG0750@2|Bacteria,1MU91@1224|Proteobacteria,42NJ0@68525|delta/epsilon subdivisions,2WJ7A@28221|Deltaproteobacteria,2MIEV@213118|Desulfobacterales	28221|Deltaproteobacteria	M	SMART PDZ DHR GLGF domain protein	rseP	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_M50
k141_2501_2	1304885.AUEY01000006_gene718	2.51e-178	531.0	COG0046@1|root,COG0046@2|Bacteria,1MYN4@1224|Proteobacteria,42M08@68525|delta/epsilon subdivisions,2WITS@28221|Deltaproteobacteria,2MIFX@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C,PurS
k141_3596_1	352165.HMPREF7215_2470	1.01e-09	62.8	COG0446@1|root,COG0446@2|Bacteria,3TA18@508458|Synergistetes	508458|Synergistetes	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2
k141_3596_2	520999.PROVALCAL_02343	7.55e-90	280.0	COG0579@1|root,COG0579@2|Bacteria,1N0QB@1224|Proteobacteria,1RN24@1236|Gammaproteobacteria,3Z7B2@586|Providencia	1236|Gammaproteobacteria	S	FAD dependent oxidoreductase	-	-	1.1.5.3	ko:K00111	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	DAO,Fer2_BFD
k141_791_1	1121324.CLIT_23c01490	1.39e-62	199.0	COG0500@1|root,COG2226@2|Bacteria,1VK9C@1239|Firmicutes,24RPV@186801|Clostridia	186801|Clostridia	Q	ubiE/COQ5 methyltransferase family	-	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11
k141_791_2	1391646.AVSU01000037_gene2094	7.89e-197	571.0	COG3829@1|root,COG3829@2|Bacteria,1TP0E@1239|Firmicutes,247MB@186801|Clostridia,25QR6@186804|Peptostreptococcaceae	186801|Clostridia	K	Sigma-54 interaction domain protein	ygeV	-	-	-	-	-	-	-	-	-	-	-	HTH_8,PAS,PAS_9,Sigma54_activat,SpoVT_C
k141_791_3	1408422.JHYF01000009_gene2020	3.15e-93	276.0	COG0634@1|root,COG0634@2|Bacteria,1V2K7@1239|Firmicutes,248P7@186801|Clostridia,36F2B@31979|Clostridiaceae	186801|Clostridia	F	Belongs to the purine pyrimidine phosphoribosyltransferase family	hpt	-	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS16720	Pribosyltran
k141_791_4	702450.CUW_1344	1.47e-67	215.0	COG2171@1|root,COG2171@2|Bacteria,1TQUJ@1239|Firmicutes,3VPZK@526524|Erysipelotrichia	526524|Erysipelotrichia	E	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate	dapD	-	-	-	-	-	-	-	-	-	-	-	DapH_N,Hexapep
k141_791_5	1033810.HLPCO_001459	1.4e-77	241.0	COG0289@1|root,COG0289@2|Bacteria,2NPX5@2323|unclassified Bacteria	2|Bacteria	E	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate	dapB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	iLJ478.TM1520	DapB_C,DapB_N
k141_791_6	1499684.CCNP01000020_gene2496	8.22e-127	370.0	COG0329@1|root,COG0329@2|Bacteria,1TPCK@1239|Firmicutes,247T5@186801|Clostridia,36DMX@31979|Clostridiaceae	186801|Clostridia	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
k141_791_7	536227.CcarbDRAFT_1027	1.46e-167	476.0	COG0136@1|root,COG0136@2|Bacteria,1TPC6@1239|Firmicutes,248ZR@186801|Clostridia,36DDT@31979|Clostridiaceae	186801|Clostridia	E	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate	asd	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
k141_791_8	1408823.AXUS01000016_gene1037	5.69e-140	409.0	COG1473@1|root,COG1473@2|Bacteria,1TPD7@1239|Firmicutes,248AH@186801|Clostridia,25R7F@186804|Peptostreptococcaceae	186801|Clostridia	E	Psort location Cytoplasmic, score 8.87	dapL	-	3.5.1.47	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	M00525	R02733	RC00064,RC00300	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
k141_791_9	1280692.AUJL01000013_gene3271	1.15e-11	72.0	COG1266@1|root,COG1266@2|Bacteria,1VAFM@1239|Firmicutes,24DNF@186801|Clostridia	186801|Clostridia	S	CAAX amino terminal protease family protein	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
k141_791_10	1301100.HG529385_gene5101	1.84e-93	281.0	COG0500@1|root,COG2226@2|Bacteria,1TQUF@1239|Firmicutes,25E3F@186801|Clostridia,36UHC@31979|Clostridiaceae	186801|Clostridia	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
k141_791_11	888064.HMPREF9088_1817	8.42e-29	104.0	COG1278@1|root,COG1278@2|Bacteria,1VEE0@1239|Firmicutes,4HNJC@91061|Bacilli,4B3ES@81852|Enterococcaceae	91061|Bacilli	K	'Cold-shock' DNA-binding domain	cspA	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
k141_791_12	1511.CLOST_0638	7.86e-125	365.0	COG1281@1|root,COG1281@2|Bacteria,1TRCH@1239|Firmicutes,24940@186801|Clostridia,25QSQ@186804|Peptostreptococcaceae	186801|Clostridia	O	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress	hslO	-	-	ko:K04083	-	-	-	-	ko00000,ko03110	-	-	-	HSP33
k141_791_13	240302.BN982_00115	4.57e-87	290.0	COG3290@1|root,COG3829@1|root,COG3290@2|Bacteria,COG3829@2|Bacteria,1TP0E@1239|Firmicutes,4HADT@91061|Bacilli,3NE2G@45667|Halobacillus	91061|Bacilli	KT	Bacterial regulatory protein, Fis family	bkdR	-	-	-	-	-	-	-	-	-	-	-	DapB_N,HTH_8,PAS,Sigma54_activat
k141_791_14	1121324.CLIT_23c01630	6.56e-230	640.0	COG0626@1|root,COG0626@2|Bacteria,1TPC7@1239|Firmicutes,25E6I@186801|Clostridia,25QSK@186804|Peptostreptococcaceae	186801|Clostridia	E	Cys/Met metabolism PLP-dependent enzyme	megL	-	2.5.1.48,4.4.1.11	ko:K01739,ko:K01761	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017	R00654,R00999,R01288,R02508,R03217,R03260,R04770,R04944,R04945,R04946	RC00020,RC00056,RC00069,RC00196,RC00348,RC00420,RC01209,RC01210,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000	-	-	-	Cys_Met_Meta_PP
k141_791_15	1321779.HMPREF1984_00459	9.24e-216	619.0	COG0737@1|root,COG0737@2|Bacteria,3795N@32066|Fusobacteria	32066|Fusobacteria	F	Belongs to the 5'-nucleotidase family	-	-	3.1.3.6,3.1.4.16	ko:K01119	ko00230,ko00240,map00230,map00240	-	R01562,R01877,R02148,R02370,R03537,R03538,R03929,R05135	RC00078,RC00296	ko00000,ko00001,ko01000	-	-	-	5_nucleotid_C,Metallophos
k141_791_16	1476973.JMMB01000007_gene3067	1.69e-133	399.0	COG1508@1|root,COG1508@2|Bacteria,1TQ0H@1239|Firmicutes,2480F@186801|Clostridia,25R2W@186804|Peptostreptococcaceae	186801|Clostridia	K	RNA polymerase	rpoN	-	-	ko:K03092	ko02020,ko05111,map02020,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma54_AID,Sigma54_CBD,Sigma54_DBD
k141_791_17	1511.CLOST_0641	4.81e-115	344.0	COG2390@1|root,COG2390@2|Bacteria,1TP62@1239|Firmicutes,24B2X@186801|Clostridia,25SNA@186804|Peptostreptococcaceae	186801|Clostridia	K	Putative sugar-binding domain	cggR	-	-	ko:K05311	-	-	-	-	ko00000,ko03000	-	-	-	Sugar-bind
k141_791_18	1304284.L21TH_1220	3.86e-177	501.0	COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,36DD0@31979|Clostridiaceae	186801|Clostridia	G	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	gap	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
k141_791_19	929506.CbC4_0572	2.24e-232	646.0	COG0126@1|root,COG0126@2|Bacteria,1TP3H@1239|Firmicutes,248VS@186801|Clostridia,36ETN@31979|Clostridiaceae	186801|Clostridia	F	Belongs to the phosphoglycerate kinase family	pgk	-	2.7.2.3,5.3.1.1	ko:K00927,ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01015,R01512	RC00002,RC00043,RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
k141_791_20	1151292.QEW_3795	1.84e-131	378.0	COG0149@1|root,COG0149@2|Bacteria,1TP2F@1239|Firmicutes,248JN@186801|Clostridia,25QK7@186804|Peptostreptococcaceae	186801|Clostridia	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	-	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iHN637.CLJU_RS19265	TIM
k141_791_21	1031288.AXAA01000021_gene2426	1.38e-250	701.0	COG0696@1|root,COG0696@2|Bacteria,1TPM4@1239|Firmicutes,247JG@186801|Clostridia,36EXB@31979|Clostridiaceae	186801|Clostridia	G	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate	gpmI	-	5.4.2.12	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,Phosphodiest,iPGM_N
k141_791_22	1121289.JHVL01000018_gene624	1.91e-240	669.0	COG0148@1|root,COG0148@2|Bacteria,1TP2S@1239|Firmicutes,247TU@186801|Clostridia,36ET7@31979|Clostridiaceae	186801|Clostridia	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
k141_791_23	1286171.EAL2_c15780	3.8e-26	98.2	COG1314@1|root,COG1314@2|Bacteria,1UA33@1239|Firmicutes,25N7X@186801|Clostridia,25XP1@186806|Eubacteriaceae	186801|Clostridia	U	Preprotein translocase SecG subunit	secG	-	-	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecG
k141_791_24	1408422.JHYF01000004_gene1470	0.0	996.0	COG3808@1|root,COG3808@2|Bacteria,1TNZI@1239|Firmicutes,248KS@186801|Clostridia,36G29@31979|Clostridiaceae	186801|Clostridia	C	Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na( ) movement across the membrane	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase
k141_2954_17	675813.VIB_002476	1.54e-240	669.0	COG0364@1|root,COG0364@2|Bacteria,1MUN0@1224|Proteobacteria,1RN76@1236|Gammaproteobacteria,1XSC7@135623|Vibrionales	135623|Vibrionales	G	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone	zwf	-	1.1.1.363,1.1.1.49	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	M00004,M00006,M00008	R00835,R02736,R10907	RC00001,RC00066	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	G6PD_C,G6PD_N
k141_679_1	1463926.JOCA01000001_gene4707	8.25e-22	97.4	COG0019@1|root,COG0454@1|root,COG0019@2|Bacteria,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	speC	-	4.1.1.17,4.1.1.20	ko:K01581,ko:K01586	ko00300,ko00330,ko00480,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map00330,map00480,map01100,map01110,map01120,map01130,map01230	M00016,M00134,M00525,M00526,M00527	R00451,R00670	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	iJN746.PP_0864	Acetyltransf_1,Orn_Arg_deC_N,Orn_DAP_Arg_deC
k141_679_2	675817.VDA_003170	1.4e-23	99.0	COG2081@1|root,COG2081@2|Bacteria,1MUGC@1224|Proteobacteria,1RNCW@1236|Gammaproteobacteria,1XSRR@135623|Vibrionales	135623|Vibrionales	S	HI0933-like protein	yhiN	-	-	ko:K07007	-	-	-	-	ko00000	-	-	-	HI0933_like
k141_680_2	1265505.ATUG01000001_gene4407	2.91e-32	118.0	2EBDE@1|root,330KY@2|Bacteria,1R3KB@1224|Proteobacteria,43DKM@68525|delta/epsilon subdivisions,2X8RT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_2955_1	314292.VAS14_21197	1.56e-24	95.9	COG1553@1|root,COG1553@2|Bacteria,1N021@1224|Proteobacteria,1S99J@1236|Gammaproteobacteria,1XXDD@135623|Vibrionales	135623|Vibrionales	P	conserved protein involved in intracellular sulfur reduction	tusD	-	-	ko:K07235	ko04122,map04122	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	DrsE
k141_2955_2	29495.EA26_19780	2.24e-150	425.0	COG2964@1|root,COG2964@2|Bacteria,1MU5K@1224|Proteobacteria,1RPDQ@1236|Gammaproteobacteria,1XT3M@135623|Vibrionales	135623|Vibrionales	S	protein conserved in bacteria	yheO	-	-	-	-	-	-	-	-	-	-	-	HTH_22,PAS_6
k141_958_2	177437.HRM2_08590	1.07e-188	535.0	COG1533@1|root,COG1533@2|Bacteria,1NWJ9@1224|Proteobacteria,42P30@68525|delta/epsilon subdivisions,2WIPV@28221|Deltaproteobacteria,2MHKC@213118|Desulfobacterales	28221|Deltaproteobacteria	L	radical SAM domain protein	-	-	4.1.99.14	ko:K03716	-	-	-	-	ko00000,ko01000	-	-	-	-
k141_5302_1	879305.HMPREF9290_1569	3.08e-19	89.7	COG0037@1|root,COG0037@2|Bacteria,1TPXP@1239|Firmicutes,248TY@186801|Clostridia,22G6X@1570339|Peptoniphilaceae	186801|Clostridia	D	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	6.3.4.19	ko:K04075	-	-	R09597	RC02633,RC02634	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3,TilS,TilS_C
k141_5302_2	986075.CathTA2_2226	7.96e-28	112.0	COG0576@1|root,COG0576@2|Bacteria,1V6G2@1239|Firmicutes,4HIRK@91061|Bacilli	91061|Bacilli	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	GO:0000166,GO:0000774,GO:0001871,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0008150,GO:0009986,GO:0017076,GO:0030234,GO:0030246,GO:0030247,GO:0030554,GO:0036094,GO:0044464,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363,GO:2001065	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
k141_2956_1	1469948.JPNB01000001_gene2028	2.7e-71	233.0	COG2376@1|root,COG2376@2|Bacteria,1TP92@1239|Firmicutes,2488D@186801|Clostridia,36E0T@31979|Clostridiaceae	186801|Clostridia	G	Dihydroxyacetone kinase DhaK, subunit	dhaK	-	2.7.1.121,2.7.1.28,2.7.1.29,4.6.1.15	ko:K00863,ko:K05878	ko00051,ko00561,ko00680,ko01100,ko01120,ko01200,ko04622,map00051,map00561,map00680,map01100,map01120,map01200,map04622	M00344	R01011,R01012,R01059	RC00002,RC00015,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Dak1,Dak2
k141_3296_66	672.VV93_v1c06890	7.44e-63	196.0	COG0517@1|root,COG0517@2|Bacteria,1N0EB@1224|Proteobacteria,1S9TG@1236|Gammaproteobacteria,1XX1F@135623|Vibrionales	135623|Vibrionales	S	acetoin utilization protein	-	-	-	-	-	-	-	-	-	-	-	-	CBS
k141_3296_67	243277.VC_0732	6.14e-175	492.0	COG0583@1|root,COG0583@2|Bacteria,1MVA1@1224|Proteobacteria,1RPAJ@1236|Gammaproteobacteria,1XSIX@135623|Vibrionales	135623|Vibrionales	K	Transcriptional regulator	-	-	-	ko:K04761	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_1,LysR_substrate
k141_3296_68	675813.VIB_001872	3.87e-116	335.0	COG0450@1|root,COG0450@2|Bacteria,1MWPY@1224|Proteobacteria,1RN4S@1236|Gammaproteobacteria,1XSFY@135623|Vibrionales	135623|Vibrionales	O	COG0450 Peroxiredoxin	-	-	1.11.1.15	ko:K03386	ko04214,map04214	-	-	-	ko00000,ko00001,ko01000,ko04147	-	-	-	1-cysPrx_C,AhpC-TSA
k141_3296_69	1348635.BBJY01000023_gene1989	1.97e-139	397.0	COG0704@1|root,COG0704@2|Bacteria,1MUMI@1224|Proteobacteria,1RMW5@1236|Gammaproteobacteria,1XSNM@135623|Vibrionales	135623|Vibrionales	P	Plays a role in the regulation of phosphate uptake	phoU	-	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
k141_3296_70	1116375.VEJY3_02635	2.29e-167	471.0	COG1117@1|root,COG1117@2|Bacteria,1MU16@1224|Proteobacteria,1RNUF@1236|Gammaproteobacteria,1XSAI@135623|Vibrionales	135623|Vibrionales	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	GO:0003674,GO:0003824,GO:0005215,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015114,GO:0015318,GO:0015399,GO:0015405,GO:0015415,GO:0015698,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0034220,GO:0035435,GO:0042623,GO:0042626,GO:0043225,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0098656,GO:0098660,GO:0098661,GO:0099133	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
k141_3296_71	55601.VANGNB10_cI0646	6.42e-243	684.0	COG0581@1|root,COG0581@2|Bacteria,1MUWB@1224|Proteobacteria,1RPV9@1236|Gammaproteobacteria,1XTB7@135623|Vibrionales	135623|Vibrionales	P	phosphate transport system	pstA	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
k141_3296_72	55601.VANGNB10_cI0645	4.04e-261	746.0	COG4590@1|root,COG4590@2|Bacteria,1QTTD@1224|Proteobacteria,1T1GK@1236|Gammaproteobacteria,1XSKV@135623|Vibrionales	135623|Vibrionales	P	phosphate ABC transporter, permease	-	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
k141_3296_73	243277.VC_0721	9.37e-156	446.0	COG0226@1|root,COG0226@2|Bacteria,1MVXP@1224|Proteobacteria,1RQDH@1236|Gammaproteobacteria,1XTH3@135623|Vibrionales	135623|Vibrionales	P	Phosphate ABC transporter, periplasmic phosphate-binding protein	-	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
k141_3296_76	675815.VOA_000876	3.55e-166	470.0	COG2974@1|root,COG2974@2|Bacteria,1MXPR@1224|Proteobacteria,1RMNN@1236|Gammaproteobacteria,1XT7H@135623|Vibrionales	135623|Vibrionales	L	May be involved in recombination	rdgC	-	-	ko:K03554	-	-	-	-	ko00000,ko03400	-	-	-	RdgC
k141_3296_77	675814.VIC_002049	0.0	867.0	COG0826@1|root,COG0826@2|Bacteria,1MUQG@1224|Proteobacteria,1RNPY@1236|Gammaproteobacteria,1XU66@135623|Vibrionales	135623|Vibrionales	O	COG0826 Collagenase and related proteases	-	-	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_U32,Peptidase_U32_C
k141_3296_79	672.VV93_v1c32170	1.01e-115	337.0	COG0778@1|root,COG0778@2|Bacteria,1NIJ8@1224|Proteobacteria,1RMRT@1236|Gammaproteobacteria,1XTEA@135623|Vibrionales	135623|Vibrionales	C	NAD(P)h-flavin oxidoreductase	nfsA	-	1.5.1.38	ko:K10678,ko:K19285	ko00633,ko00740,ko01100,ko01120,map00633,map00740,map01100,map01120	-	R05706,R08014,R08017,R08042	RC00126,RC00250	ko00000,ko00001,ko01000	-	-	-	Nitroreductase
k141_3296_80	1487923.DP73_17110	1.02e-24	97.1	COG1942@1|root,COG1942@2|Bacteria,1VA6U@1239|Firmicutes,24MXT@186801|Clostridia,265UI@186807|Peptococcaceae	186801|Clostridia	S	Domain of unknown function (DUF1904)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1904
k141_3296_81	342564.Q1I119_9CAUD	1.93e-85	267.0	4QAQE@10239|Viruses,4QUYF@35237|dsDNA viruses  no RNA stage,4QPDM@28883|Caudovirales,4QI35@10662|Myoviridae	10662|Myoviridae	S	DNA integration	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_3296_82	214092.YPO2125	3.28e-13	70.5	2DM22@1|root,31DR9@2|Bacteria,1RJ1F@1224|Proteobacteria,1S7FV@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Arc-like DNA binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Arc
k141_3296_85	945543.VIBR0546_09092	1.45e-24	94.4	2B6Q4@1|root,31ZNW@2|Bacteria,1QKII@1224|Proteobacteria,1TINS@1236|Gammaproteobacteria,1XZDW@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_3296_86	796620.VIBC2010_18709	1.93e-184	532.0	28HIF@1|root,2Z7TX@2|Bacteria,1MY24@1224|Proteobacteria,1RN69@1236|Gammaproteobacteria,1XWMY@135623|Vibrionales	135623|Vibrionales	S	Bacteriophage replication gene A protein (GPA)	-	-	-	-	-	-	-	-	-	-	-	-	Phage_GPA
k141_2663_1	674977.VMC_36910	1.73e-114	345.0	COG0281@1|root,COG0281@2|Bacteria,1MU0A@1224|Proteobacteria,1RQ11@1236|Gammaproteobacteria,1XTTY@135623|Vibrionales	135623|Vibrionales	C	malic enzyme	maeA	GO:0003674,GO:0003824,GO:0004470,GO:0004473,GO:0006082,GO:0006090,GO:0006108,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0019752,GO:0032787,GO:0043436,GO:0043648,GO:0044237,GO:0044281,GO:0055114,GO:0071704	1.1.1.38	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	-	R00214	RC00105	ko00000,ko00001,ko01000	-	-	-	Malic_M,malic
k141_2663_2	243277.VC_1187	2.06e-40	137.0	2BZ4P@1|root,32Z0A@2|Bacteria,1N883@1224|Proteobacteria,1SD9J@1236|Gammaproteobacteria,1XYPV@135623|Vibrionales	135623|Vibrionales	S	Protein of unknown function (DUF3392)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3392
k141_2663_3	675813.VIB_001469	5.6e-97	291.0	COG2949@1|root,COG2949@2|Bacteria,1MURW@1224|Proteobacteria,1RMG7@1236|Gammaproteobacteria,1XSGW@135623|Vibrionales	135623|Vibrionales	S	SanA protein	sanA	-	-	ko:K03748	-	-	-	-	ko00000	-	-	-	DUF218
k141_3298_1	398512.JQKC01000013_gene1464	6.21e-39	139.0	COG5113@1|root,COG3236@2|Bacteria,1UY8T@1239|Firmicutes,2486K@186801|Clostridia,3WGS9@541000|Ruminococcaceae	186801|Clostridia	O	Domain of unknown function (DUF1768)	-	-	-	ko:K09935	-	-	-	-	ko00000	-	-	-	DUF1768
k141_2979_1	717231.Flexsi_0928	2.83e-212	598.0	COG0733@1|root,COG0733@2|Bacteria,2GGE6@200930|Deferribacteres	200930|Deferribacteres	P	Sodium:neurotransmitter symporter family	-	-	-	ko:K03308	-	-	-	-	ko00000	2.A.22.4,2.A.22.5	-	-	SNF
k141_2664_1	1121403.AUCV01000052_gene2565	4.39e-153	455.0	COG1629@1|root,COG4771@2|Bacteria,1MXY7@1224|Proteobacteria,42MSN@68525|delta/epsilon subdivisions,2WIK9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	TonB-dependent Receptor Plug	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
k141_1663_1	55601.VANGNB10_cI0869	3.96e-66	229.0	COG3170@1|root,COG3170@2|Bacteria,1MXV7@1224|Proteobacteria,1RMM5@1236|Gammaproteobacteria,1XUV6@135623|Vibrionales	135623|Vibrionales	NU	COG3170 Tfp pilus assembly protein FimV	-	-	-	ko:K08086	-	-	-	-	ko00000	-	-	-	-
k141_1663_2	1219065.VPR01S_02_01230	1.47e-165	466.0	COG0101@1|root,COG0101@2|Bacteria,1MUYI@1224|Proteobacteria,1RMK2@1236|Gammaproteobacteria,1XTDP@135623|Vibrionales	135623|Vibrionales	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
k141_1663_3	29495.EA26_16770	1.52e-15	74.7	COG0777@1|root,COG0777@2|Bacteria,1MW8G@1224|Proteobacteria,1RNDS@1236|Gammaproteobacteria,1XUF4@135623|Vibrionales	135623|Vibrionales	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA	accD	GO:0003674,GO:0003824,GO:0003989,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009317,GO:0009987,GO:0016053,GO:0016421,GO:0016874,GO:0016885,GO:0019752,GO:0032787,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901576,GO:1902494	2.1.3.15,6.4.1.2	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
k141_981_1	1304885.AUEY01000005_gene781	4.28e-88	266.0	COG1338@1|root,COG1338@2|Bacteria,1MVBU@1224|Proteobacteria,42NDZ@68525|delta/epsilon subdivisions,2WKCN@28221|Deltaproteobacteria,2MHSW@213118|Desulfobacterales	28221|Deltaproteobacteria	N	Plays a role in the flagellum-specific transport system	fliP	-	-	ko:K02419	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	FliP
k141_981_2	1304885.AUEY01000005_gene780	2.48e-37	127.0	COG1987@1|root,COG1987@2|Bacteria,1N73W@1224|Proteobacteria,42VAB@68525|delta/epsilon subdivisions,2WR6X@28221|Deltaproteobacteria,2MKJM@213118|Desulfobacterales	28221|Deltaproteobacteria	N	Role in flagellar biosynthesis	fliQ	-	-	ko:K02420,ko:K03227	ko02040,ko03070,map02040,map03070	M00332,M00542,M00660	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.6.1,3.A.6.2,3.A.6.3	-	-	Bac_export_3
k141_981_3	879212.DespoDRAFT_00558	8.37e-71	225.0	COG1684@1|root,COG1684@2|Bacteria,1NIF4@1224|Proteobacteria,42NX7@68525|delta/epsilon subdivisions,2WQ35@28221|Deltaproteobacteria,2MIN6@213118|Desulfobacterales	28221|Deltaproteobacteria	N	Role in flagellar biosynthesis	fliR	-	-	ko:K02421	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	Bac_export_1
k141_981_4	1395587.P364_0110855	9.11e-78	250.0	COG1377@1|root,COG1377@2|Bacteria,1TPRP@1239|Firmicutes,4HB7Y@91061|Bacilli,26TRR@186822|Paenibacillaceae	91061|Bacilli	N	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin	flhB	-	-	ko:K02401	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	Bac_export_2
k141_981_5	1304885.AUEY01000005_gene777	0.0	893.0	COG1298@1|root,COG1298@2|Bacteria,1MUF3@1224|Proteobacteria,42NB2@68525|delta/epsilon subdivisions,2WIWG@28221|Deltaproteobacteria,2MI0U@213118|Desulfobacterales	28221|Deltaproteobacteria	N	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin	flhA	-	-	ko:K02400	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	FHIPEP
k141_981_6	177437.HRM2_37110	2.6e-79	255.0	COG1419@1|root,COG1419@2|Bacteria,1MUQW@1224|Proteobacteria,42NBF@68525|delta/epsilon subdivisions,2WNW9@28221|Deltaproteobacteria,2MHZE@213118|Desulfobacterales	28221|Deltaproteobacteria	N	PFAM SRP54-type protein, GTPase domain	flhF	-	-	ko:K02404	-	-	-	-	ko00000,ko02035	-	-	-	SRP54
k141_981_7	1121396.KB893069_gene1382	2.66e-89	275.0	COG0455@1|root,COG0455@2|Bacteria,1R8IW@1224|Proteobacteria,42PF7@68525|delta/epsilon subdivisions,2WJB5@28221|Deltaproteobacteria,2MIVC@213118|Desulfobacterales	28221|Deltaproteobacteria	D	Belongs to the ParA family	flhG	-	-	ko:K04562	-	-	-	-	ko00000,ko02035	-	-	-	AAA_31,CbiA,ParA
k141_981_8	1304880.JAGB01000001_gene214	2.27e-45	159.0	COG1191@1|root,COG1191@2|Bacteria,1TP9K@1239|Firmicutes,248M0@186801|Clostridia	186801|Clostridia	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	fliA	-	-	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	-	-	-	ko00000,ko00001,ko02035,ko03021	-	-	-	Sigma70_r2,Sigma70_r3,Sigma70_r4
k141_2665_1	1167006.UWK_03167	9.93e-22	95.1	COG1509@1|root,COG1509@2|Bacteria,1MUPJ@1224|Proteobacteria,42MNR@68525|delta/epsilon subdivisions,2WJ70@28221|Deltaproteobacteria,2MICE@213118|Desulfobacterales	28221|Deltaproteobacteria	C	TIGRFAM lysine 2,3-aminomutase YodO family protein	-	-	5.4.3.2	ko:K01843	ko00310,map00310	-	R00461	RC00303	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Fer4_14,LAM_C,Radical_SAM
k141_2665_2	109760.SPPG_07775T0	1.02e-19	86.7	COG0071@1|root,KOG0710@2759|Eukaryota	2759|Eukaryota	O	response to heat	-	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0006457,GO:0006950,GO:0006986,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0010033,GO:0033554,GO:0034605,GO:0034620,GO:0035966,GO:0035967,GO:0042221,GO:0042802,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044464,GO:0050896,GO:0051082,GO:0051716,GO:0051788,GO:0061077,GO:0070887,GO:0071218,GO:0071310	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
k141_3300_1	1051646.VITU9109_24975	1.96e-24	103.0	COG1263@1|root,COG1264@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,1MY1V@1224|Proteobacteria,1RMYZ@1236|Gammaproteobacteria,1XTN9@135623|Vibrionales	135623|Vibrionales	G	COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific	-	-	2.7.1.193	ko:K02803,ko:K02804	ko00520,ko02060,map00520,map02060	M00267	R05199	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.1.1.15,4.A.1.1.2,4.A.1.1.5,4.A.1.1.7	-	-	PTS_EIIB,PTS_EIIC
k141_3300_2	349521.HCH_05438	5.89e-76	230.0	COG0454@1|root,COG0456@2|Bacteria,1RCYQ@1224|Proteobacteria,1S3YJ@1236|Gammaproteobacteria,1XRX2@135619|Oceanospirillales	135619|Oceanospirillales	K	Acetyltransferase (GNAT) domain	-	-	2.3.1.57	ko:K00657	ko00330,ko01100,ko04216,map00330,map01100,map04216	M00135	R01154	RC00004,RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetyltransf_1
k141_984_1	1121396.KB893054_gene2430	1.79e-120	357.0	COG1160@1|root,COG1160@2|Bacteria,1MU9S@1224|Proteobacteria,42M3N@68525|delta/epsilon subdivisions,2WISS@28221|Deltaproteobacteria,2MHQH@213118|Desulfobacterales	28221|Deltaproteobacteria	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	-	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
k141_3301_1	941770.GL622179_gene412	1.39e-11	65.5	2DSV3@1|root,33HII@2|Bacteria,1VQ64@1239|Firmicutes,4IGTW@91061|Bacilli,3F8RY@33958|Lactobacillaceae	91061|Bacilli	S	ORF located using Blastx	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_1664_1	1105031.HMPREF1141_1614	1.37e-79	251.0	COG1012@1|root,COG1012@2|Bacteria,1TP4S@1239|Firmicutes,247W7@186801|Clostridia,36DK7@31979|Clostridiaceae	186801|Clostridia	C	Belongs to the aldehyde dehydrogenase family	mmsA	-	1.2.1.18,1.2.1.27	ko:K00140	ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200	M00013	R00705,R00706,R00922,R00935	RC00004,RC02723,RC02817	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
k141_1664_2	55601.VANGNB10_cII0974c	9.83e-263	754.0	COG3409@1|root,COG3501@1|root,COG3409@2|Bacteria,COG3501@2|Bacteria,1MU7Q@1224|Proteobacteria,1RMZS@1236|Gammaproteobacteria,1XUHW@135623|Vibrionales	135623|Vibrionales	M	protein conserved in bacteria	vgrG1	GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0006464,GO:0006807,GO:0006996,GO:0007010,GO:0007015,GO:0008144,GO:0008150,GO:0008152,GO:0008154,GO:0009405,GO:0009987,GO:0016043,GO:0016874,GO:0016879,GO:0016881,GO:0017076,GO:0018149,GO:0018153,GO:0018193,GO:0018199,GO:0018205,GO:0018262,GO:0018995,GO:0019538,GO:0022411,GO:0030029,GO:0030036,GO:0030042,GO:0030430,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032984,GO:0033643,GO:0033646,GO:0035639,GO:0036094,GO:0036211,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0043624,GO:0043656,GO:0043657,GO:0043933,GO:0044215,GO:0044216,GO:0044217,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044419,GO:0046872,GO:0051261,GO:0051704,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:0097435,GO:1901265,GO:1901363,GO:1901564	-	ko:K11904	ko03070,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	PG_binding_1,Phage_GPD
k141_1665_1	1348635.BBJY01000023_gene1976	4.27e-37	127.0	COG1942@1|root,COG1942@2|Bacteria,1N7M2@1224|Proteobacteria,1SCAG@1236|Gammaproteobacteria,1XY1W@135623|Vibrionales	135623|Vibrionales	S	Domain of unknown function (DUF1904)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1904
k141_2980_1	55601.VANGNB10_cI0471c	6.03e-30	119.0	COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,1RNV0@1236|Gammaproteobacteria,1XV78@135623|Vibrionales	135623|Vibrionales	U	COG1459 Type II secretory pathway, component PulF	pilC	GO:0002790,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008104,GO:0008150,GO:0009297,GO:0009306,GO:0009987,GO:0015031,GO:0015628,GO:0015833,GO:0016020,GO:0016043,GO:0022607,GO:0030030,GO:0030031,GO:0032940,GO:0033036,GO:0042886,GO:0043711,GO:0044085,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0098776	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
k141_2980_2	345073.VC395_2541	4.87e-111	330.0	COG1989@1|root,COG1989@2|Bacteria,1MUZF@1224|Proteobacteria,1RN90@1236|Gammaproteobacteria,1XTYX@135623|Vibrionales	135623|Vibrionales	NOU	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue	pilD	-	3.4.23.43	ko:K02654	-	M00331	-	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	3.A.15.2	-	-	DiS_P_DiS,Peptidase_A24
k141_2980_3	1051646.VITU9109_25900	2.78e-85	257.0	COG0237@1|root,COG0237@2|Bacteria,1RCXT@1224|Proteobacteria,1S3NR@1236|Gammaproteobacteria,1XW2K@135623|Vibrionales	135623|Vibrionales	F	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A	coaE	GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.1.24	ko:K00859	ko00770,ko01100,map00770,map01100	M00120	R00130	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CoaE
k141_2980_4	675815.VOA_002739	2.2e-136	390.0	COG4582@1|root,COG4582@2|Bacteria,1MW69@1224|Proteobacteria,1RNPD@1236|Gammaproteobacteria,1XT60@135623|Vibrionales	135623|Vibrionales	D	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity	zapD	GO:0000003,GO:0000910,GO:0005575,GO:0005623,GO:0007049,GO:0008150,GO:0009987,GO:0019954,GO:0022402,GO:0022414,GO:0032153,GO:0032505,GO:0043093,GO:0044464,GO:0051301	-	ko:K18778	-	-	-	-	ko00000,ko03036	-	-	-	ZapD
k141_2980_5	466088.CL42_16245	5.38e-221	618.0	COG3550@1|root,COG3550@2|Bacteria,1PD1S@1224|Proteobacteria,1RXIE@1236|Gammaproteobacteria,3NMG6@468|Moraxellaceae	1236|Gammaproteobacteria	S	HipA-like C-terminal domain	-	-	2.7.11.1	ko:K07154	-	-	-	-	ko00000,ko01000,ko01001,ko02048	-	-	-	Couple_hipA,HipA_C
k141_2980_6	1217714.F975_03061	8.85e-39	130.0	COG1396@1|root,COG1396@2|Bacteria,1N5Q5@1224|Proteobacteria,1SB34@1236|Gammaproteobacteria,3NPFT@468|Moraxellaceae	1236|Gammaproteobacteria	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19,HTH_3
k141_985_5	1410619.SRDD_34980	4.6e-06	50.1	COG1349@1|root,COG1349@2|Bacteria,1MUJG@1224|Proteobacteria,1RNW4@1236|Gammaproteobacteria,402TD@613|Serratia	1236|Gammaproteobacteria	K	DeoR C terminal sensor domain	-	-	-	ko:K02081,ko:K02444,ko:K03477	-	-	-	-	ko00000,ko03000	-	-	-	DeoRC,HTH_DeoR
k141_5340_1	1280001.BAOA01000018_gene328	2.55e-148	425.0	COG1477@1|root,COG1477@2|Bacteria,1MW6K@1224|Proteobacteria,1RNMZ@1236|Gammaproteobacteria,1XW9Z@135623|Vibrionales	135623|Vibrionales	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	-	-	-	-	-	-	-	-	-	-	-	-	ApbE
k141_5340_2	1280001.BAOA01000018_gene329	0.0	1751.0	COG1053@1|root,COG1902@1|root,COG1053@2|Bacteria,COG1902@2|Bacteria,1MVIX@1224|Proteobacteria,1T1RB@1236|Gammaproteobacteria,1XV9S@135623|Vibrionales	135623|Vibrionales	C	FMN_bind	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_2,FMN_bind,Oxidored_FMN
k141_5340_3	400668.Mmwyl1_4143	5.72e-186	521.0	COG0583@1|root,COG0583@2|Bacteria,1N663@1224|Proteobacteria,1SN55@1236|Gammaproteobacteria,1XKEG@135619|Oceanospirillales	135619|Oceanospirillales	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
k141_5340_5	1049564.TevJSym_bh00200	4.86e-118	339.0	COG1592@1|root,COG1592@2|Bacteria,1R9WG@1224|Proteobacteria,1S25G@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	PFAM Rubrerythrin	-	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
k141_5340_6	1348635.BBJY01000009_gene1496	3.88e-73	223.0	COG1438@1|root,COG1438@2|Bacteria,1QC5E@1224|Proteobacteria,1S1KR@1236|Gammaproteobacteria,1XW92@135623|Vibrionales	135623|Vibrionales	K	Regulates arginine biosynthesis genes	ARGR	-	-	ko:K03402	-	-	-	-	ko00000,ko03000	-	-	-	Arg_repressor,Arg_repressor_C
k141_5340_8	55601.VANGNB10_cI2449	5.53e-160	455.0	COG0549@1|root,COG0549@2|Bacteria,1MWXC@1224|Proteobacteria,1RP78@1236|Gammaproteobacteria,1XVZA@135623|Vibrionales	135623|Vibrionales	E	Belongs to the carbamate kinase family	arcC	-	2.7.2.2	ko:K00926	ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200	-	R00150,R01395	RC00002,RC00043,RC02803,RC02804	ko00000,ko00001,ko01000	-	-	-	AA_kinase
k141_5340_9	1219065.VPR01S_26_00360	2.26e-255	704.0	COG2235@1|root,COG2235@2|Bacteria,1NCGV@1224|Proteobacteria,1RM99@1236|Gammaproteobacteria,1XSY4@135623|Vibrionales	135623|Vibrionales	E	COG2235 Arginine deiminase	arcA	GO:0008150,GO:0008152,GO:0008218,GO:0009987,GO:0044237	3.5.3.6	ko:K01478	ko00220,ko01100,ko01110,ko01130,map00220,map01100,map01110,map01130	-	R00552	RC00177	ko00000,ko00001,ko01000	-	-	-	Amidinotransf
k141_1666_1	55601.VANGNB10_cII0227	3.75e-23	94.7	COG4604@1|root,COG4604@2|Bacteria,1QU78@1224|Proteobacteria,1RP3Y@1236|Gammaproteobacteria,1XVHH@135623|Vibrionales	135623|Vibrionales	P	abc transporter atp-binding protein	vctC	-	3.6.3.34	ko:K02013	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	ABC_tran
k141_1666_2	243277.VC_A0229	6.83e-145	417.0	COG4605@1|root,COG4605@2|Bacteria,1NM9D@1224|Proteobacteria,1S2GB@1236|Gammaproteobacteria,1XV8U@135623|Vibrionales	135623|Vibrionales	P	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily	-	-	-	ko:K02015	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	FecCD
k141_1666_3	55601.VANGNB10_cII0225	1e-41	145.0	COG4606@1|root,COG4606@2|Bacteria,1MVSV@1224|Proteobacteria,1RQCK@1236|Gammaproteobacteria,1XTVI@135623|Vibrionales	135623|Vibrionales	P	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily	vctD	-	-	ko:K02015	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	FecCD
k141_2982_1	1517681.HW45_22965	6.58e-106	311.0	COG0235@1|root,COG0235@2|Bacteria,1MXV2@1224|Proteobacteria,1RP50@1236|Gammaproteobacteria,1XWCD@135623|Vibrionales	135623|Vibrionales	G	Rhamnulose-1-phosphate aldolase	-	-	4.1.2.19	ko:K01629	ko00040,ko00051,ko01120,map00040,map00051,map01120	-	R01785,R02263	RC00438,RC00599,RC00603,RC00604	ko00000,ko00001,ko01000	-	-	-	Aldolase_II
k141_2983_1	1121342.AUCO01000017_gene2877	0.000498	47.0	COG0500@1|root,COG0789@1|root,COG0789@2|Bacteria,COG2226@2|Bacteria,1TSDZ@1239|Firmicutes,248EY@186801|Clostridia,36EQV@31979|Clostridiaceae	186801|Clostridia	KQ	helix_turn_helix, mercury resistance	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1,Methyltransf_11,Methyltransf_25,Methyltransf_31
k141_986_1	1121406.JAEX01000011_gene2038	5.65e-54	181.0	COG0639@1|root,COG0639@2|Bacteria,1MUV1@1224|Proteobacteria,42RNB@68525|delta/epsilon subdivisions,2WNEW@28221|Deltaproteobacteria,2MBFV@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	PFAM Metallophosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos_2
k141_986_2	555500.I215_04675	2.63e-05	52.4	COG1705@1|root,COG1705@2|Bacteria,4NEER@976|Bacteroidetes,1HYCP@117743|Flavobacteriia	976|Bacteroidetes	NU	Mannosyl-glycoprotein	lytG	-	-	-	-	-	-	-	-	-	-	-	Glucosaminidase,LysM
k141_986_3	1232437.KL662027_gene2814	1.59e-58	194.0	COG1262@1|root,COG1262@2|Bacteria,1NQ5K@1224|Proteobacteria,42NWH@68525|delta/epsilon subdivisions,2WP4R@28221|Deltaproteobacteria,2MKAG@213118|Desulfobacterales	28221|Deltaproteobacteria	KLT	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
k141_1667_1	314260.PB2503_07007	1.02e-19	95.9	COG4247@1|root,COG4247@2|Bacteria,1MVTA@1224|Proteobacteria,2TUDJ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	3-phytase	phy	-	3.1.3.8	ko:K01083	ko00562,map00562	-	R03371	RC00078	ko00000,ko00001,ko01000	-	-	-	Phytase
k141_1667_2	526222.Desal_0543	4.23e-154	455.0	COG5001@1|root,COG5001@2|Bacteria,1QW5S@1224|Proteobacteria,43D0Q@68525|delta/epsilon subdivisions,2X88J@28221|Deltaproteobacteria,2M8F0@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GGDEF,PAS_3
k141_987_1	1224318.DT73_22570	2.71e-35	126.0	COG3628@1|root,COG3628@2|Bacteria,1N23A@1224|Proteobacteria,1SCDV@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	GPW gp25 family protein	-	-	-	ko:K06903	-	-	-	-	ko00000	-	-	-	GPW_gp25
k141_2984_1	1046724.KB889881_gene1813	1.62e-19	84.7	2DBEM@1|root,2Z8SV@2|Bacteria,1R5QV@1224|Proteobacteria,1S0BT@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Domain of unknown function (DUF4433)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4433
k141_2984_2	78398.KS43_20510	5.39e-157	451.0	COG2110@1|root,COG2110@2|Bacteria,1MVYN@1224|Proteobacteria,1RNHW@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	phosphatase homologous to the C-terminal domain of histone macroH2A1	-	-	-	-	-	-	-	-	-	-	-	-	Macro
k141_1668_1	1188252.AJYK01000118_gene873	1.01e-107	322.0	COG0677@1|root,COG0677@2|Bacteria,1MUC6@1224|Proteobacteria,1RMX0@1236|Gammaproteobacteria,1XSY5@135623|Vibrionales	135623|Vibrionales	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	-	-	-	ko:K02474	ko00520,map00520	-	R06894	RC00291	ko00000,ko00001,ko01000,ko01005	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
k141_2667_1	1219076.N646_3950	3.97e-149	427.0	COG4989@1|root,COG4989@2|Bacteria,1MY3G@1224|Proteobacteria,1RRIC@1236|Gammaproteobacteria,1XTIM@135623|Vibrionales	135623|Vibrionales	S	oxidoreductase, aldo keto reductase 2	ydhF	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
k141_2667_2	675814.VIC_001412	5.23e-29	108.0	2C4GN@1|root,2ZHR0@2|Bacteria,1P917@1224|Proteobacteria,1STX2@1236|Gammaproteobacteria,1XY3H@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	PilZ
k141_2667_3	595494.Tola_1712	2.08e-168	481.0	COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,1S1KQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	PFAM ABC transporter related	-	-	-	ko:K10112	ko02010,map02010	M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1	-	-	ABC_tran,TOBE_2
k141_4436_50	1031288.AXAA01000016_gene987	4.67e-56	211.0	COG3383@1|root,COG3383@2|Bacteria,1TT6D@1239|Firmicutes,24YN9@186801|Clostridia,36UKJ@31979|Clostridiaceae	186801|Clostridia	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	fdhA	-	1.17.1.10,1.17.1.11,1.17.1.9	ko:K00123,ko:K05299,ko:K22341	ko00630,ko00680,ko00720,ko01100,ko01120,ko01200,map00630,map00680,map00720,map01100,map01120,map01200	M00377	R00134,R00519	RC02796	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_4,Fer4,Fer4_7,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
k141_4436_52	1321814.HMPREF9089_00089	5.16e-18	98.6	COG4249@1|root,COG4249@2|Bacteria,1U39P@1239|Firmicutes,24AUW@186801|Clostridia	186801|Clostridia	S	Caspase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C14,SLH
k141_61_1	745776.DGo_CA1901	3.38e-25	109.0	COG1566@1|root,COG5280@1|root,COG1566@2|Bacteria,COG5280@2|Bacteria	2|Bacteria	NT	Phage tail tape measure protein TP901	-	-	-	ko:K02005,ko:K02022	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,PhageMin_Tail
k141_2749_1	243277.VC_0780	2.85e-32	124.0	COG2977@1|root,COG2977@2|Bacteria,1MZK2@1224|Proteobacteria,1S968@1236|Gammaproteobacteria,1XYU9@135623|Vibrionales	135623|Vibrionales	Q	Belongs to the P-Pant transferase superfamily	-	-	6.3.2.14	ko:K02362	ko01053,ko01110,ko01130,map01053,map01110,map01130	-	R07644	RC00162,RC03046	ko00000,ko00001,ko01000	-	-	-	ACPS
k141_2749_2	1499689.CCNN01000007_gene2326	5.31e-27	111.0	COG2207@1|root,COG2207@2|Bacteria,1TS8C@1239|Firmicutes,25AZI@186801|Clostridia,36W6W@31979|Clostridiaceae	186801|Clostridia	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
k141_62_1	1121918.ARWE01000001_gene1693	1.15e-55	183.0	COG1296@1|root,COG1296@2|Bacteria,1P6U3@1224|Proteobacteria,42QVQ@68525|delta/epsilon subdivisions,2WMW1@28221|Deltaproteobacteria,43T17@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	AzlC protein	-	-	-	-	-	-	-	-	-	-	-	-	AzlC
k141_374_1	1051646.VITU9109_24765	1.02e-113	353.0	COG0826@1|root,COG0826@2|Bacteria,1MUQG@1224|Proteobacteria,1RN7S@1236|Gammaproteobacteria,1XUBV@135623|Vibrionales	135623|Vibrionales	O	COG0826 Collagenase and related proteases	-	-	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	DUF3656,Peptidase_U32
k141_3411_2	237368.SCABRO_03556	3.22e-41	164.0	COG1357@1|root,COG1357@2|Bacteria,2J0M1@203682|Planctomycetes	203682|Planctomycetes	S	Pentapeptide repeats (9 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Pentapeptide
k141_3411_3	118005.AWNK01000005_gene1471	1.07e-54	192.0	COG0683@1|root,COG0683@2|Bacteria	2|Bacteria	E	ABC-type branched-chain amino acid transport systems, periplasmic component	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6,cNMP_binding
k141_3411_4	572544.Ilyop_1852	3.47e-31	126.0	COG1181@1|root,COG1181@2|Bacteria,378CP@32066|Fusobacteria	32066|Fusobacteria	F	Belongs to the D-alanine--D-alanine ligase family	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
k141_3411_5	640511.BC1002_5456	1.11e-51	186.0	COG1301@1|root,COG1301@2|Bacteria,1PK6C@1224|Proteobacteria,2VM58@28216|Betaproteobacteria,1K6H6@119060|Burkholderiaceae	28216|Betaproteobacteria	P	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family	-	-	-	-	-	-	-	-	-	-	-	-	SDF
k141_3411_6	398579.Spea_1239	1.34e-05	54.7	COG0834@1|root,COG1301@1|root,COG0834@2|Bacteria,COG1301@2|Bacteria,1P22C@1224|Proteobacteria,1RSGY@1236|Gammaproteobacteria,2QBG7@267890|Shewanellaceae	1236|Gammaproteobacteria	P	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3,SDF
k141_3411_7	1430440.MGMSRv2_1635	6.59e-35	134.0	COG0834@1|root,COG0834@2|Bacteria,1R5TJ@1224|Proteobacteria,2UEY6@28211|Alphaproteobacteria,2JXNK@204441|Rhodospirillales	204441|Rhodospirillales	ET	Bacterial periplasmic substrate-binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_3
k141_3411_8	1116375.VEJY3_07785	2.55e-90	269.0	COG0110@1|root,COG0110@2|Bacteria,1RA2T@1224|Proteobacteria,1S3ZZ@1236|Gammaproteobacteria,1XUHN@135623|Vibrionales	135623|Vibrionales	S	COG0110 Acetyltransferase (isoleucine patch superfamily)	-	-	2.3.1.79	ko:K00661	-	-	-	-	ko00000,ko01000	-	-	-	Hexapep,Hexapep_2,Mac
k141_3411_9	1219065.VPR01S_12_00720	1.08e-162	462.0	COG1683@1|root,COG3272@1|root,COG1683@2|Bacteria,COG3272@2|Bacteria,1MXYZ@1224|Proteobacteria,1RNMF@1236|Gammaproteobacteria,1XUJK@135623|Vibrionales	135623|Vibrionales	S	Protein of unknown function (DUF1722)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1722,DUF523
k141_3411_10	1517681.HW45_09440	2.1e-135	394.0	COG1609@1|root,COG1609@2|Bacteria,1NZH0@1224|Proteobacteria,1RPMC@1236|Gammaproteobacteria,1Y0AS@135623|Vibrionales	135623|Vibrionales	K	helix_turn _helix lactose operon repressor	-	-	-	-	-	-	-	-	-	-	-	-	LacI,Peripla_BP_3
k141_3411_11	298386.PBPRB2005	3.51e-47	153.0	COG1447@1|root,COG1447@2|Bacteria,1RI0T@1224|Proteobacteria,1S75F@1236|Gammaproteobacteria,1XXTR@135623|Vibrionales	135623|Vibrionales	G	Phosphotransferase system cellobiose-specific component IIA	celC	-	2.7.1.196,2.7.1.205	ko:K02759	ko00500,ko02060,map00500,map02060	M00275	R11170,R11172	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.3.2	-	-	PTS_IIA
k141_3411_12	298386.PBPRB2006	4.75e-266	737.0	COG2723@1|root,COG2723@2|Bacteria,1MWG6@1224|Proteobacteria,1RMM2@1236|Gammaproteobacteria,1XSV6@135623|Vibrionales	135623|Vibrionales	G	Belongs to the glycosyl hydrolase 1 family	-	-	3.2.1.86	ko:K01223	ko00010,ko00500,map00010,map00500	-	R00839,R05133,R05134	RC00049,RC00171,RC00714	ko00000,ko00001,ko01000	-	GT1	-	Glyco_hydro_1
k141_3411_13	1517681.HW45_09450	5.72e-263	727.0	COG1455@1|root,COG1455@2|Bacteria,1MXAG@1224|Proteobacteria,1RQGX@1236|Gammaproteobacteria,1XTD1@135623|Vibrionales	135623|Vibrionales	G	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane	-	-	-	ko:K02761	ko00500,ko02060,map00500,map02060	M00275	R11170,R11172	RC00017,RC03206	ko00000,ko00001,ko00002,ko02000	4.A.3.2	-	-	PTS_EIIC
k141_3411_14	298386.PBPRB2008	6.77e-44	145.0	COG1440@1|root,COG1440@2|Bacteria,1RJE9@1224|Proteobacteria,1S7CQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	PTS system, Lactose/Cellobiose specific IIB subunit	-	-	2.7.1.196,2.7.1.205	ko:K02760	ko00500,ko02060,map00500,map02060	M00275	R11170,R11172	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.3.2	-	-	PTS_IIB
k141_3411_15	1517681.HW45_09460	1.05e-206	584.0	COG1455@1|root,COG1455@2|Bacteria,1PVNT@1224|Proteobacteria,1RR0W@1236|Gammaproteobacteria,1Y0BD@135623|Vibrionales	135623|Vibrionales	G	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane	-	-	-	ko:K02761	ko00500,ko02060,map00500,map02060	M00275	R11170,R11172	RC00017,RC03206	ko00000,ko00001,ko00002,ko02000	4.A.3.2	-	-	PTS_EIIC
k141_3411_16	1410618.JNKI01000035_gene2043	6.42e-111	338.0	COG3203@1|root,COG3203@2|Bacteria,1V0I8@1239|Firmicutes,4H3D3@909932|Negativicutes	909932|Negativicutes	M	S-layer homology domain	-	-	-	-	-	-	-	-	-	-	-	-	SLH
k141_3411_17	469595.CSAG_01427	5e-126	368.0	COG1227@1|root,COG1227@2|Bacteria,1P9JN@1224|Proteobacteria,1RZSV@1236|Gammaproteobacteria,3WXCQ@544|Citrobacter	1236|Gammaproteobacteria	C	DHHA2	ppaC	-	3.6.1.1	ko:K15986	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	DHH,DHHA2
k141_3411_18	29495.EA26_13820	2.59e-20	83.2	COG2991@1|root,COG2991@2|Bacteria,1NI0R@1224|Proteobacteria,1SGJF@1236|Gammaproteobacteria,1XYXD@135623|Vibrionales	135623|Vibrionales	S	protein conserved in bacteria	-	-	-	ko:K05952	-	-	-	-	ko00000	-	-	-	NqrM
k141_3411_19	29495.EA26_07605	1.56e-45	153.0	COG0454@1|root,COG0456@2|Bacteria,1N2EC@1224|Proteobacteria,1RS2A@1236|Gammaproteobacteria,1XXK0@135623|Vibrionales	135623|Vibrionales	K	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
k141_3411_20	55601.VANGNB10_cI1225c	2.06e-132	382.0	COG0561@1|root,COG0561@2|Bacteria,1MXIH@1224|Proteobacteria,1RQH8@1236|Gammaproteobacteria,1XUBE@135623|Vibrionales	135623|Vibrionales	S	hydrolases of the HAD superfamily	yidA	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
k141_375_1	1121396.KB893046_gene3302	2.94e-35	142.0	COG0840@1|root,COG4191@1|root,COG0840@2|Bacteria,COG4191@2|Bacteria,1MU9B@1224|Proteobacteria,42MBK@68525|delta/epsilon subdivisions,2WKDV@28221|Deltaproteobacteria,2MINH@213118|Desulfobacterales	28221|Deltaproteobacteria	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal,dCache_1
k141_65_1	1236541.BALL01000067_gene4776	4.91e-106	316.0	COG0686@1|root,COG0686@2|Bacteria,1QTX1@1224|Proteobacteria,1T1JB@1236|Gammaproteobacteria,2Q9T8@267890|Shewanellaceae	1236|Gammaproteobacteria	C	Belongs to the AlaDH PNT family	ald	-	1.4.1.1	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	-	R00396	RC00008	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
k141_2056_1	316067.Geob_3196	1.77e-10	69.3	COG3409@1|root,COG3409@2|Bacteria,1N9AN@1224|Proteobacteria,42XYC@68525|delta/epsilon subdivisions,2WSN6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	peptidoglycan-binding domain-containing protein	-	-	-	ko:K17733	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	PG_binding_1,VanY
k141_2056_3	87626.PTD2_21812	4.1e-123	364.0	COG3385@1|root,COG3385@2|Bacteria,1R55Y@1224|Proteobacteria,1RRSD@1236|Gammaproteobacteria,2Q2U3@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	L	PFAM transposase, IS4	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
k141_1738_1	1304885.AUEY01000126_gene667	4.87e-211	602.0	COG1418@1|root,COG1418@2|Bacteria,1P7YA@1224|Proteobacteria,42KZ8@68525|delta/epsilon subdivisions,2WJG1@28221|Deltaproteobacteria,2MHS7@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Endoribonuclease that initiates mRNA decay	rny	-	-	ko:K18682	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DUF3552,HD,KH_1
k141_1738_2	1304885.AUEY01000126_gene666	4.54e-189	539.0	COG0162@1|root,COG0162@2|Bacteria,1MVUQ@1224|Proteobacteria,42N2A@68525|delta/epsilon subdivisions,2WIP6@28221|Deltaproteobacteria,2MI9Q@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
k141_66_1	675813.VIB_001099	3.45e-149	434.0	COG0297@1|root,COG0297@2|Bacteria,1MUGM@1224|Proteobacteria,1RNMP@1236|Gammaproteobacteria,1XSTA@135623|Vibrionales	135623|Vibrionales	F	Synthesizes alpha-1,4-glucan chains using ADP-glucose	glgA	GO:0000271,GO:0003674,GO:0003824,GO:0004373,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0008194,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0035251,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046527,GO:0055114,GO:0071704,GO:1901576	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Glyco_transf_5,Glycos_transf_1
k141_1739_1	1304885.AUEY01000021_gene3460	8.64e-45	150.0	COG1832@1|root,COG1832@2|Bacteria,1N03D@1224|Proteobacteria,42TZA@68525|delta/epsilon subdivisions,2WRHK@28221|Deltaproteobacteria,2MQ00@213118|Desulfobacterales	28221|Deltaproteobacteria	S	CoA binding domain	-	-	-	ko:K06929	-	-	-	-	ko00000	-	-	-	CoA_binding_2
k141_1739_2	1121434.AULY01000006_gene541	1.45e-31	121.0	COG0546@1|root,COG0546@2|Bacteria,1MY9Y@1224|Proteobacteria,42SSC@68525|delta/epsilon subdivisions,2WN7Q@28221|Deltaproteobacteria,2MBNQ@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant	-	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
k141_1050_1	1120970.AUBZ01000023_gene2830	1.34e-111	342.0	COG3345@1|root,COG3345@2|Bacteria,1MWTQ@1224|Proteobacteria,1RQ4M@1236|Gammaproteobacteria,465XZ@72275|Alteromonadaceae	1236|Gammaproteobacteria	G	Glycosyl hydrolase family 36 N-terminal domain	rafA	-	3.2.1.22	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	-	R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091	RC00049,RC00059,RC00451	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_36C,Glyco_hydro_36N,Melibiase
k141_1050_2	298386.PBPRB1779	4.31e-40	136.0	COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,1SCA7@1236|Gammaproteobacteria,1XYBB@135623|Vibrionales	135623|Vibrionales	K	COG1278 Cold shock proteins	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
k141_1050_3	1348635.BBJY01000010_gene1353	2.54e-180	506.0	COG4977@1|root,COG4977@2|Bacteria,1MUDK@1224|Proteobacteria,1RP9W@1236|Gammaproteobacteria,1XVCQ@135623|Vibrionales	135623|Vibrionales	K	COG4977 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain	-	-	-	-	-	-	-	-	-	-	-	-	DJ-1_PfpI,HTH_18,HTH_AraC
k141_1050_4	1348635.BBJY01000010_gene1352	3.98e-89	265.0	COG1335@1|root,COG1335@2|Bacteria,1RDHA@1224|Proteobacteria,1S6WV@1236|Gammaproteobacteria,1XX0V@135623|Vibrionales	135623|Vibrionales	Q	Isochorismatase family	-	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase
k141_1050_5	357804.Ping_2019	0.0	1277.0	COG3250@1|root,COG3250@2|Bacteria,1MVBN@1224|Proteobacteria,1RMER@1236|Gammaproteobacteria,2QHS1@267894|Psychromonadaceae	1236|Gammaproteobacteria	G	Beta galactosidase small chain	lacZ	GO:0000287,GO:0003674,GO:0003824,GO:0004553,GO:0004565,GO:0005488,GO:0005515,GO:0005575,GO:0005975,GO:0005984,GO:0005988,GO:0005990,GO:0008150,GO:0008152,GO:0009056,GO:0009311,GO:0009313,GO:0009341,GO:0009987,GO:0015925,GO:0016052,GO:0016787,GO:0016798,GO:0031420,GO:0032991,GO:0042802,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044275,GO:0046352,GO:0046872,GO:0071704,GO:1901575,GO:1902494	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	iAF1260.b0344,iB21_1397.B21_00302,iECBD_1354.ECBD_3313,iECB_1328.ECB_00298,iECDH1ME8569_1439.ECDH1ME8569_0331,iECD_1391.ECD_00298,iECNA114_1301.ECNA114_0327,iEcDH1_1363.EcDH1_3262,iJO1366.b0344,iJR904.b0344,iY75_1357.Y75_RS01775	Bgal_small_N,DUF4981,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
k141_1050_6	754436.JCM19237_5028	7.8e-204	574.0	COG2211@1|root,COG2211@2|Bacteria,1MVUM@1224|Proteobacteria,1RP5J@1236|Gammaproteobacteria,1XT0V@135623|Vibrionales	135623|Vibrionales	G	COG2211 Na melibiose symporter and related transporters	-	-	-	ko:K11104	-	-	-	-	ko00000,ko02000	2.A.2.1	-	-	MFS_2
k141_68_1	269799.Gmet_1403	6.03e-29	114.0	COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,42NSM@68525|delta/epsilon subdivisions,2WJXQ@28221|Deltaproteobacteria,43RXP@69541|Desulfuromonadales	28221|Deltaproteobacteria	V	PFAM ABC transporter related	pilH	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
k141_68_2	933262.AXAM01000028_gene3329	3.28e-20	91.3	COG1277@1|root,COG1277@2|Bacteria,1RM0H@1224|Proteobacteria,42T8A@68525|delta/epsilon subdivisions,2WPQJ@28221|Deltaproteobacteria,2MKG3@213118|Desulfobacterales	28221|Deltaproteobacteria	S	ABC-type transport system involved in multi-copper enzyme maturation permease component	pilI	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_2,ABC2_membrane_4
k141_1740_1	933262.AXAM01000036_gene2181	4.45e-20	94.4	COG1197@1|root,COG1197@2|Bacteria,1MUXG@1224|Proteobacteria,42N8X@68525|delta/epsilon subdivisions,2WIVR@28221|Deltaproteobacteria,2MI3P@213118|Desulfobacterales	28221|Deltaproteobacteria	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
k141_1394_2	672.VV93_v1c19030	3.32e-60	221.0	COG2200@1|root,COG2200@2|Bacteria,1N299@1224|Proteobacteria,1RQI1@1236|Gammaproteobacteria,1XTPK@135623|Vibrionales	135623|Vibrionales	T	COG2202 FOG PAS PAC domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,EAL,PAS
k141_1394_3	1121374.KB891576_gene746	1.53e-70	221.0	COG0300@1|root,COG0300@2|Bacteria,1QUVN@1224|Proteobacteria,1T22I@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	csgA	-	-	-	-	-	-	-	-	-	-	-	adh_short
k141_1394_4	1348635.BBJY01000001_gene2572	5.15e-272	796.0	COG2982@1|root,COG2982@2|Bacteria,1MUME@1224|Proteobacteria,1RNPC@1236|Gammaproteobacteria,1XSPR@135623|Vibrionales	135623|Vibrionales	M	Domain of Unknown Function (DUF748)	-	-	-	-	-	-	-	-	-	-	-	-	DUF748
k141_1394_6	1208321.D104_01225	2.12e-190	551.0	COG1463@1|root,COG3008@1|root,COG1463@2|Bacteria,COG3008@2|Bacteria,1MU1T@1224|Proteobacteria,1RN89@1236|Gammaproteobacteria,1XIA2@135619|Oceanospirillales	135619|Oceanospirillales	Q	Paraquat-inducible protein B	pqiB	-	-	ko:K06192	-	-	-	-	ko00000	-	-	-	MlaD
k141_1394_7	400668.Mmwyl1_2933	6.64e-135	400.0	COG2995@1|root,COG2995@2|Bacteria,1MWG1@1224|Proteobacteria,1RM9Z@1236|Gammaproteobacteria,1XIA3@135619|Oceanospirillales	135619|Oceanospirillales	S	paraquat-inducible protein A	pqiA	-	-	ko:K03808	-	-	-	-	ko00000	-	-	-	PqiA
k141_1394_8	1151116.Q7S_12895	4.16e-72	225.0	COG0176@1|root,COG0176@2|Bacteria,1MWQ8@1224|Proteobacteria,1RNWN@1236|Gammaproteobacteria,3FH46@34037|Rahnella	1236|Gammaproteobacteria	H	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	fsa	-	-	ko:K08313,ko:K08314	-	-	-	-	ko00000,ko01000	-	-	-	TAL_FSA
k141_1394_9	1214065.BAGV01000014_gene3092	1.01e-97	293.0	COG1349@1|root,COG1349@2|Bacteria,1MV49@1224|Proteobacteria,1RRR5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	transcriptional regulator	glpR_2	-	-	-	-	-	-	-	-	-	-	-	DeoRC,HTH_DeoR
k141_1394_10	314345.SPV1_05053	2.5e-45	150.0	2DMKI@1|root,32S70@2|Bacteria,1N1FV@1224|Proteobacteria	1224|Proteobacteria	S	SpoIIAA-like	VVA0543	-	-	-	-	-	-	-	-	-	-	-	SpoIIAA-like
k141_69_1	1121396.KB893118_gene3103	1.05e-29	116.0	COG0465@1|root,COG0465@2|Bacteria,1MU6J@1224|Proteobacteria,42M4Z@68525|delta/epsilon subdivisions,2WJZ3@28221|Deltaproteobacteria,2MN0D@213118|Desulfobacterales	28221|Deltaproteobacteria	O	Peptidase family M41	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
k141_69_2	1121396.KB893077_gene734	7.48e-106	315.0	COG2199@1|root,COG3706@2|Bacteria,1RERI@1224|Proteobacteria,42S3X@68525|delta/epsilon subdivisions,2WNF2@28221|Deltaproteobacteria,2MNCH@213118|Desulfobacterales	28221|Deltaproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	iAF987.Gmet_2982	GGDEF
k141_378_1	1121403.AUCV01000045_gene1163	2.16e-112	361.0	COG1629@1|root,COG4771@2|Bacteria,1MWKN@1224|Proteobacteria,42MNM@68525|delta/epsilon subdivisions,2WMEW@28221|Deltaproteobacteria,2MMGV@213118|Desulfobacterales	28221|Deltaproteobacteria	P	TonB dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
k141_3413_2	1122236.KB905142_gene339	2.44e-92	292.0	COG0389@1|root,COG0389@2|Bacteria,1MUUH@1224|Proteobacteria,2VHHK@28216|Betaproteobacteria,2KM3P@206350|Nitrosomonadales	206350|Nitrosomonadales	L	PFAM UMUC domain protein DNA-repair protein	-	-	-	ko:K03502	-	-	-	-	ko00000,ko03400	-	-	-	DUF4113,IMS,IMS_C,IMS_HHH
k141_3413_3	1541065.JRFE01000039_gene6447	3.33e-49	161.0	COG1974@1|root,COG1974@2|Bacteria,1G6T1@1117|Cyanobacteria	1117|Cyanobacteria	KT	Belongs to the peptidase S24 family	umuD	-	-	ko:K03503	-	-	-	-	ko00000,ko01000,ko01002,ko03400	-	-	-	Peptidase_S24
k141_3413_4	1245471.PCA10_16100	1.19e-77	244.0	COG0697@1|root,COG0697@2|Bacteria,1PX5W@1224|Proteobacteria,1S266@1236|Gammaproteobacteria,1YD6V@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
k141_2059_1	672.VV93_v1c43960	3.09e-31	128.0	COG3209@1|root,COG3209@2|Bacteria,1PDT2@1224|Proteobacteria,1TEF8@1236|Gammaproteobacteria,1XZDG@135623|Vibrionales	135623|Vibrionales	M	COG3209 Rhs family protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_1741_1	765913.ThidrDRAFT_3032	2.2e-52	177.0	COG0834@1|root,COG0834@2|Bacteria,1RCKS@1224|Proteobacteria,1S33Q@1236|Gammaproteobacteria,1WXZA@135613|Chromatiales	135613|Chromatiales	ET	Periplasmic component of amino acid ABC-type transporter signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_3
k141_1741_2	1230342.CTM_02019	3.2e-101	307.0	COG0277@1|root,COG0277@2|Bacteria,1TPBC@1239|Firmicutes,24A99@186801|Clostridia,36DRC@31979|Clostridiaceae	186801|Clostridia	C	FAD linked oxidase domain protein	glcD1	-	1.1.3.15	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
k141_3414_1	1238450.VIBNISOn1_1370015	7.77e-103	307.0	COG1879@1|root,COG1879@2|Bacteria,1NRXG@1224|Proteobacteria,1RPBV@1236|Gammaproteobacteria,1XUF5@135623|Vibrionales	1236|Gammaproteobacteria	G	ABC-type sugar transport system, periplasmic component	rbsB	-	-	ko:K10439,ko:K10549	ko02010,ko02030,map02010,map02030	M00212,M00217	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19,3.A.1.2.6	-	-	Peripla_BP_4
k141_2750_1	1348635.BBJY01000005_gene3256	1.87e-143	437.0	COG3008@1|root,COG3008@2|Bacteria,1MU1T@1224|Proteobacteria,1RN89@1236|Gammaproteobacteria,1XTE9@135623|Vibrionales	135623|Vibrionales	Q	Paraquat-inducible protein B	-	-	-	-	-	-	-	-	-	-	-	-	MlaD
k141_2750_2	945550.VISI1226_13883	9.04e-106	324.0	COG2995@1|root,COG2995@2|Bacteria,1MWG1@1224|Proteobacteria,1RM9Z@1236|Gammaproteobacteria,1XT4U@135623|Vibrionales	135623|Vibrionales	S	paraquat-inducible protein A	-	-	-	ko:K03808	-	-	-	-	ko00000	-	-	-	PqiA
k141_2750_3	345073.VC395_1618	7.19e-81	244.0	COG1956@1|root,COG1956@2|Bacteria,1RDBM@1224|Proteobacteria,1S6QU@1236|Gammaproteobacteria,1XX5M@135623|Vibrionales	135623|Vibrionales	T	GAF domain-containing protein	yebR	-	1.8.4.14	ko:K08968	ko00270,map00270	-	R02025	RC00639	ko00000,ko00001,ko01000	-	-	-	GAF_2
k141_2750_4	1517681.HW45_25120	1.09e-106	312.0	COG3109@1|root,COG3109@2|Bacteria,1N68T@1224|Proteobacteria,1RP4S@1236|Gammaproteobacteria,1XT78@135623|Vibrionales	135623|Vibrionales	J	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities	proQ	-	-	ko:K03607	-	-	-	-	ko00000	-	-	-	ProQ,ProQ_C
k141_2750_5	55601.VANGNB10_cI1256	2.33e-301	836.0	COG0793@1|root,COG0793@2|Bacteria,1MU39@1224|Proteobacteria,1RMSR@1236|Gammaproteobacteria,1XT5Z@135623|Vibrionales	135623|Vibrionales	M	protease	prc	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	BAGE,DUF3340,PDZ,Peptidase_S41
k141_1395_1	1304885.AUEY01000008_gene2058	1.23e-10	60.1	2DE6G@1|root,32U2S@2|Bacteria,1N4FF@1224|Proteobacteria,42TMY@68525|delta/epsilon subdivisions,2WQEV@28221|Deltaproteobacteria,2MKMW@213118|Desulfobacterales	28221|Deltaproteobacteria	S	PFAM ATP synthase I chain	-	-	-	-	-	-	-	-	-	-	-	-	ATP-synt_I
k141_3100_1	177437.HRM2_24380	1.47e-116	360.0	COG0243@1|root,COG1846@1|root,COG0243@2|Bacteria,COG1846@2|Bacteria,1NR6J@1224|Proteobacteria,42NEV@68525|delta/epsilon subdivisions,2WJD0@28221|Deltaproteobacteria,2MHX6@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Molybdopterin oxidoreductase Fe4S4 domain	-	-	-	-	-	-	-	-	-	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
k141_3443_1	1150600.ADIARSV_2278	3.36e-47	162.0	COG1131@1|root,COG1131@2|Bacteria,4NFRV@976|Bacteroidetes,1IQ31@117747|Sphingobacteriia	976|Bacteroidetes	V	ABC transporter	cbiO	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
k141_3768_2	1517681.HW45_21815	3.96e-75	226.0	COG0346@1|root,COG0346@2|Bacteria,1RCYX@1224|Proteobacteria,1S1Z9@1236|Gammaproteobacteria,1XX01@135623|Vibrionales	135623|Vibrionales	E	Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione	gloA	GO:0003674,GO:0003824,GO:0004462,GO:0006518,GO:0006575,GO:0006749,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016846,GO:0034641,GO:0043603,GO:0044237,GO:0051186,GO:0071704,GO:1901564	4.4.1.5	ko:K01759	ko00620,map00620	-	R02530	RC00004,RC00740	ko00000,ko00001,ko01000	-	-	-	Glyoxalase
k141_3768_3	55601.VANGNB10_cI0878	1.39e-147	422.0	COG2885@1|root,COG2885@2|Bacteria,1PGGZ@1224|Proteobacteria,1RNFU@1236|Gammaproteobacteria,1XUNB@135623|Vibrionales	135623|Vibrionales	N	flagellar protein MotY	motY	-	-	ko:K21218	ko02040,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	OmpA
k141_3768_4	1219065.VPR01S_02_00740	1.27e-124	358.0	COG0847@1|root,COG0847@2|Bacteria,1MUPK@1224|Proteobacteria,1RMMH@1236|Gammaproteobacteria,1XUNE@135623|Vibrionales	135623|Vibrionales	L	Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis	rnt	GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008408,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0031123,GO:0034470,GO:0034641,GO:0034660,GO:0042780,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360	-	ko:K03683	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RNase_T
k141_401_1	633149.Bresu_0473	2.33e-24	110.0	COG4774@1|root,COG4774@2|Bacteria,1NMCN@1224|Proteobacteria,2U44P@28211|Alphaproteobacteria,2KKA0@204458|Caulobacterales	204458|Caulobacterales	P	TonB dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
k141_401_2	997346.HMPREF9374_2437	3.49e-27	114.0	COG0247@1|root,COG2181@1|root,COG0247@2|Bacteria,COG2181@2|Bacteria,1TPG1@1239|Firmicutes,4HB2J@91061|Bacilli,27BAP@186824|Thermoactinomycetaceae	91061|Bacilli	C	4Fe-4S dicluster domain	ywjF	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_8
k141_3444_1	1121440.AUMA01000008_gene804	1.27e-43	167.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42NNT@68525|delta/epsilon subdivisions,2WJDP@28221|Deltaproteobacteria,2M8A1@213115|Desulfovibrionales	28221|Deltaproteobacteria	NT	histidine kinase HAMP region domain protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,DUF3365,HAMP,MCPsignal,dCache_1
k141_3444_2	1395516.PMO01_14965	1.43e-09	61.6	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	NT	chemotaxis, protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal,dCache_1
k141_4451_2	1313421.JHBV01000004_gene740	3.33e-79	248.0	COG0535@1|root,COG0535@2|Bacteria,4P3YV@976|Bacteroidetes	976|Bacteroidetes	S	phosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
k141_4451_3	760192.Halhy_1109	3.38e-141	418.0	COG0635@1|root,COG0635@2|Bacteria,4P1HI@976|Bacteroidetes	976|Bacteroidetes	H	coproporphyrinogen III oxidase and related FeS	-	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
k141_4451_4	28072.Nos7524_5266	7.77e-117	342.0	COG3119@1|root,COG3119@2|Bacteria,1G1S4@1117|Cyanobacteria,1HRD8@1161|Nostocales	1117|Cyanobacteria	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
k141_4451_5	1906.SFRA_11850	3.07e-06	54.3	COG1011@1|root,COG1011@2|Bacteria,2GMZT@201174|Actinobacteria	201174|Actinobacteria	E	Had-superfamily hydrolase, subfamily ia, variant 1	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
k141_3445_2	1262449.CP6013_1170	1.55e-41	155.0	COG5001@1|root,COG5001@2|Bacteria,1TP8V@1239|Firmicutes,247PX@186801|Clostridia,36E1W@31979|Clostridiaceae	186801|Clostridia	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,HAMP,PAS_3,PocR,dCache_1
k141_2400_2	1304885.AUEY01000008_gene2108	7.93e-244	677.0	COG0065@1|root,COG0065@2|Bacteria,1MVYR@1224|Proteobacteria,42M5D@68525|delta/epsilon subdivisions,2WJ59@28221|Deltaproteobacteria,2MHP1@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuC	-	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase
k141_2460_2	1131462.DCF50_p213	5.35e-16	77.4	COG1910@1|root,COG3311@1|root,COG1910@2|Bacteria,COG3311@2|Bacteria,1TRH3@1239|Firmicutes,24ATZ@186801|Clostridia,2612F@186807|Peptococcaceae	186801|Clostridia	HP	TIGRFAM molybdenum cofactor synthesis	-	-	2.10.1.1	ko:K03750,ko:K07219	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	HTH_17,MoCF_biosynth,MoeA_C,MoeA_N,PBP_like
k141_2162_2	1219072.VHA01S_003_00100	7.35e-53	182.0	COG3031@1|root,COG3031@2|Bacteria,1RD3I@1224|Proteobacteria,1RQKA@1236|Gammaproteobacteria,1XU1I@135623|Vibrionales	135623|Vibrionales	U	general secretion pathway protein	epsC	GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705	-	ko:K02452	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSC
k141_2162_3	1348635.BBJY01000009_gene1461	0.0	1016.0	COG1450@1|root,COG1450@2|Bacteria,1MUUA@1224|Proteobacteria,1RPJS@1236|Gammaproteobacteria,1XSIA@135623|Vibrionales	135623|Vibrionales	NU	General secretion pathway protein	gspD	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	Secretin,Secretin_N
k141_2162_4	55601.VANGNB10_cI0156	3.06e-259	721.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,1RMBS@1236|Gammaproteobacteria,1XTS6@135623|Vibrionales	135623|Vibrionales	NU	COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB	epsE	-	-	ko:K02454	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSE
k141_2162_5	1265503.KB905163_gene2304	1.65e-51	176.0	COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,1RQ86@1236|Gammaproteobacteria,2Q5UT@267889|Colwelliaceae	1236|Gammaproteobacteria	U	Type II secretion system (T2SS), protein F	gspF	GO:0002790,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015628,GO:0015833,GO:0016020,GO:0032940,GO:0033036,GO:0042886,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098776	-	ko:K02455	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSF
k141_211_1	1565129.JSFF01000002_gene3423	3.01e-16	85.5	COG5373@1|root,COG5373@2|Bacteria,1QMXK@1224|Proteobacteria,1S7G5@1236|Gammaproteobacteria,2QA12@267890|Shewanellaceae	1236|Gammaproteobacteria	S	Predicted membrane protein (DUF2339)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2339
k141_1193_1	425104.Ssed_3198	6.2e-130	374.0	COG2834@1|root,COG2834@2|Bacteria,1R5U8@1224|Proteobacteria,1SWYR@1236|Gammaproteobacteria,2QA0Q@267890|Shewanellaceae	1236|Gammaproteobacteria	M	Outer membrane lipoprotein-sorting protein	-	-	-	-	-	-	-	-	-	-	-	-	LolA_like
k141_1193_2	945543.VIBR0546_12362	6.13e-175	501.0	COG4591@1|root,COG4591@2|Bacteria,1R4Q2@1224|Proteobacteria,1S1AK@1236|Gammaproteobacteria,1XVHA@135623|Vibrionales	135623|Vibrionales	M	FtsX-like permease family	VPA0558	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
k141_1193_3	425104.Ssed_3196	1.78e-58	197.0	COG4591@1|root,COG4591@2|Bacteria,1R4Q2@1224|Proteobacteria,1RQW0@1236|Gammaproteobacteria,2QBD2@267890|Shewanellaceae	1236|Gammaproteobacteria	M	FtsX-like permease family	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
k141_1478_1	272563.CD630_19860	6e-216	610.0	COG0621@1|root,COG0621@2|Bacteria,1TNYN@1239|Firmicutes,2482Y@186801|Clostridia,25R5Z@186804|Peptostreptococcaceae	186801|Clostridia	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
k141_1478_2	500633.CLOHIR_00552	0.0	988.0	COG0249@1|root,COG0249@2|Bacteria,1TPRJ@1239|Firmicutes,248GI@186801|Clostridia,25QVT@186804|Peptostreptococcaceae	186801|Clostridia	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	mutS	-	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
k141_1478_3	1121324.CLIT_11c02780	6.39e-164	498.0	COG0323@1|root,COG0323@2|Bacteria,1TPGK@1239|Firmicutes,24902@186801|Clostridia,25R29@186804|Peptostreptococcaceae	186801|Clostridia	L	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	mutL	-	-	ko:K03572	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	DNA_mis_repair,HATPase_c_3,MutL_C
k141_1478_4	1408823.AXUS01000031_gene1605	2.4e-118	350.0	COG0324@1|root,COG0324@2|Bacteria,1TPSC@1239|Firmicutes,248HB@186801|Clostridia,25QWB@186804|Peptostreptococcaceae	186801|Clostridia	F	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	-	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
k141_1478_5	871968.DESME_07635	5.09e-28	103.0	COG1923@1|root,COG1923@2|Bacteria,1VEGI@1239|Firmicutes,24QIM@186801|Clostridia,262GK@186807|Peptococcaceae	186801|Clostridia	J	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs	hfq	-	-	ko:K03666	ko02024,ko03018,ko05111,map02024,map03018,map05111	-	-	-	ko00000,ko00001,ko03019,ko03036	-	-	-	Hfq
k141_1478_7	1033810.HLPCO_000210	5.51e-51	172.0	COG5482@1|root,COG5482@2|Bacteria	2|Bacteria	S	Putative PD-(D/E)XK phosphodiesterase (DUF2161)	MA20_28540	-	-	-	-	-	-	-	-	-	-	-	DUF2161
k141_1478_8	1243664.CAVL020000045_gene2137	9.51e-109	321.0	COG1246@1|root,COG1246@2|Bacteria,1TRN6@1239|Firmicutes,4HB4C@91061|Bacilli,1ZFF1@1386|Bacillus	91061|Bacilli	E	YoaP-like	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,YoaP
k141_1478_9	768710.DesyoDRAFT_3994	1.32e-10	65.9	COG1396@1|root,COG1396@2|Bacteria,1VK84@1239|Firmicutes,24QK6@186801|Clostridia,2635E@186807|Peptococcaceae	186801|Clostridia	K	PFAM Helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19,HTH_3
k141_1478_10	1415775.U729_2396	2.27e-180	532.0	COG1193@1|root,COG1193@2|Bacteria,1TQWB@1239|Firmicutes,24A15@186801|Clostridia,36F5M@31979|Clostridiaceae	186801|Clostridia	L	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity	mutS5	-	-	ko:K07456	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_V
k141_1478_11	525282.HMPREF0391_11809	1.15e-35	127.0	COG0735@1|root,COG0735@2|Bacteria,1V400@1239|Firmicutes,24NZG@186801|Clostridia,22H7H@1570339|Peptoniphilaceae	186801|Clostridia	K	Belongs to the Fur family	-	-	-	ko:K03711,ko:K09825	-	-	-	-	ko00000,ko03000	-	-	-	FUR
k141_1478_12	994573.T472_0212220	2.63e-25	104.0	COG0632@1|root,COG0632@2|Bacteria,1V3KF@1239|Firmicutes,24JKV@186801|Clostridia,36IEQ@31979|Clostridiaceae	186801|Clostridia	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB	ruvA	-	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_C,RuvA_N
k141_1478_13	500633.CLOHIR_00905	7.12e-153	440.0	COG2255@1|root,COG2255@2|Bacteria,1TR47@1239|Firmicutes,247W0@186801|Clostridia,25QWA@186804|Peptostreptococcaceae	186801|Clostridia	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	-	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
k141_1478_14	1471459.JFLJ01000137_gene1206	3.69e-47	178.0	COG2385@1|root,COG2385@2|Bacteria,1G2FP@1117|Cyanobacteria,1MKZ4@1212|Prochloraceae	1117|Cyanobacteria	D	sporulation protein	spoIID	-	-	ko:K06381	-	-	-	-	ko00000	-	-	-	SpoIID
k141_1478_15	929506.CbC4_1055	1.5e-170	484.0	COG0809@1|root,COG0809@2|Bacteria,1TPKD@1239|Firmicutes,247NT@186801|Clostridia,36E77@31979|Clostridiaceae	186801|Clostridia	J	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	queA	-	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
k141_1478_16	1476973.JMMB01000007_gene672	4.15e-228	633.0	COG0343@1|root,COG0343@2|Bacteria,1TNZ4@1239|Firmicutes,247NJ@186801|Clostridia,25QE3@186804|Peptostreptococcaceae	186801|Clostridia	F	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	tgt	-	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
k141_1478_17	674977.VMC_16750	8.1e-27	124.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,1XUI8@135623|Vibrionales	135623|Vibrionales	NT	methyl-accepting chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal,dCache_1
k141_1478_18	1408823.AXUS01000008_gene2284	1.27e-14	70.5	COG1862@1|root,COG1862@2|Bacteria,1VEMC@1239|Firmicutes,24MMT@186801|Clostridia,25RND@186804|Peptostreptococcaceae	186801|Clostridia	U	Preprotein translocase, YajC subunit	yajC	-	-	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	YajC
k141_1478_20	596315.HMPREF0634_0329	4.54e-238	665.0	COG0641@1|root,COG0641@2|Bacteria,1TQPS@1239|Firmicutes,248DD@186801|Clostridia,25QV7@186804|Peptostreptococcaceae	186801|Clostridia	C	Six-Cys-in-45 modification radical SAM protein	scfB	-	-	ko:K06871	-	-	-	-	ko00000	-	-	-	Fer4_12,Radical_SAM,SPASM
k141_1478_21	1286171.EAL2_c09700	2.75e-63	199.0	COG0663@1|root,COG0663@2|Bacteria,1V6CZ@1239|Firmicutes,24JAK@186801|Clostridia,25W8Q@186806|Eubacteriaceae	186801|Clostridia	S	Bacterial transferase hexapeptide repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep,Hexapep_2
k141_1478_22	1121324.CLIT_5c01000	2.33e-187	533.0	COG0342@1|root,COG0342@2|Bacteria,1TQVT@1239|Firmicutes,247X8@186801|Clostridia,25SH1@186804|Peptostreptococcaceae	186801|Clostridia	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
k141_4913_23	1121324.CLIT_5c00690	4.2e-168	483.0	COG0475@1|root,COG0475@2|Bacteria,1TS32@1239|Firmicutes,247XW@186801|Clostridia	186801|Clostridia	P	Transporter, CPA2 family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
k141_4913_24	1304284.L21TH_1716	1.27e-38	133.0	COG0347@1|root,COG0347@2|Bacteria,1VFZ7@1239|Firmicutes,24N1M@186801|Clostridia,36KTI@31979|Clostridiaceae	186801|Clostridia	E	Belongs to the P(II) protein family	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_4913_25	868595.Desca_2263	8.69e-81	244.0	COG0622@1|root,COG0622@2|Bacteria,1V1X1@1239|Firmicutes,24GA4@186801|Clostridia,262HX@186807|Peptococcaceae	186801|Clostridia	S	Calcineurin-like phosphoesterase superfamily domain	yfcE	-	-	ko:K07095	-	-	-	-	ko00000	-	-	-	Metallophos_2
k141_4913_26	293826.Amet_3174	2.65e-110	326.0	COG0061@1|root,COG0061@2|Bacteria,1TRB3@1239|Firmicutes,24BG6@186801|Clostridia,36EBN@31979|Clostridiaceae	186801|Clostridia	H	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	nadK	-	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS05480	NAD_kinase
k141_4913_27	1121864.OMO_01296	1.77e-10	62.8	COG0110@1|root,COG1605@1|root,COG0110@2|Bacteria,COG1605@2|Bacteria,1TQEX@1239|Firmicutes,4HAJ0@91061|Bacilli,4B0HP@81852|Enterococcaceae	91061|Bacilli	E	Maltose acetyltransferase	maa	-	2.3.1.79	ko:K00661	-	-	-	-	ko00000,ko01000	-	-	-	CM_2,Hexapep,Hexapep_2,Mac
k141_4913_28	445973.CLOBAR_00817	1.82e-91	281.0	COG0564@1|root,COG0564@2|Bacteria,1TS0P@1239|Firmicutes,25CCQ@186801|Clostridia,25UMC@186804|Peptostreptococcaceae	186801|Clostridia	G	Responsible for synthesis of pseudouridine from uracil	-	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
k141_4913_29	500633.CLOHIR_01140	4.85e-13	65.1	COG0236@1|root,COG0236@2|Bacteria,1VEE3@1239|Firmicutes	1239|Firmicutes	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
k141_4913_30	1382305.AZUC01000063_gene3240	4.45e-51	171.0	COG0220@1|root,COG0220@2|Bacteria,1TQCA@1239|Firmicutes,4HC08@91061|Bacilli,26D7P@186818|Planococcaceae	91061|Bacilli	J	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA	trmB	GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234	2.1.1.33	ko:K03439	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_4
k141_4913_31	1286171.EAL2_c09550	5.05e-145	419.0	COG1609@1|root,COG1609@2|Bacteria,1TQ7K@1239|Firmicutes,247M2@186801|Clostridia,25WGG@186806|Eubacteriaceae	186801|Clostridia	K	helix_turn _helix lactose operon repressor	ccpA	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
k141_4913_32	1511.CLOST_2105	0.0	1062.0	COG1067@1|root,COG1067@2|Bacteria,1TQT5@1239|Firmicutes,248NE@186801|Clostridia	186801|Clostridia	O	Belongs to the peptidase S16 family	-	-	-	-	-	-	-	-	-	-	-	-	AAA_32,Lon_C
k141_4913_33	272563.CD630_07910	1.68e-102	302.0	COG1739@1|root,COG1739@2|Bacteria,1V6MQ@1239|Firmicutes,248W7@186801|Clostridia,25QJ6@186804|Peptostreptococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	yvyE	-	-	-	-	-	-	-	-	-	-	-	DUF1949,UPF0029
k141_4913_34	350688.Clos_1782	1.25e-43	146.0	COG1832@1|root,COG1832@2|Bacteria,1V7C7@1239|Firmicutes,24P0N@186801|Clostridia,36UCP@31979|Clostridiaceae	186801|Clostridia	S	CoA-binding domain protein	-	-	-	ko:K06929	-	-	-	-	ko00000	-	-	-	CoA_binding_2
k141_4913_35	1121289.JHVL01000010_gene1354	2.51e-116	344.0	COG0179@1|root,COG0179@2|Bacteria,1TQDQ@1239|Firmicutes,248AJ@186801|Clostridia,36EXG@31979|Clostridiaceae	186801|Clostridia	Q	PFAM fumarylacetoacetate (FAA) hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	FAA_hydrolase
k141_4913_36	1121324.CLIT_23c02770	1.77e-139	409.0	COG2865@1|root,COG2865@2|Bacteria,1UZZK@1239|Firmicutes,25CHX@186801|Clostridia	186801|Clostridia	K	PFAM AAA-4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	AlbA_2
k141_4913_37	445973.CLOBAR_02789	1.99e-183	525.0	COG1625@1|root,COG1625@2|Bacteria,1TSFU@1239|Firmicutes,247JK@186801|Clostridia,25SXA@186804|Peptostreptococcaceae	186801|Clostridia	C	Protein of unknown function (DUF512)	-	-	-	-	-	-	-	-	-	-	-	-	DUF512
k141_4913_38	596329.HMPREF0631_1838	2.57e-215	606.0	COG1160@1|root,COG1160@2|Bacteria,1TPNM@1239|Firmicutes,2493T@186801|Clostridia,25R13@186804|Peptostreptococcaceae	186801|Clostridia	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	-	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
k141_4913_39	272563.CD630_26300	1.69e-137	400.0	COG0240@1|root,COG0240@2|Bacteria,1TQ5P@1239|Firmicutes,248JT@186801|Clostridia,25QDE@186804|Peptostreptococcaceae	186801|Clostridia	I	Glycerol-3-phosphate dehydrogenase	gpsA	-	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	-	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
k141_4913_40	1511.CLOST_1882	4.65e-35	140.0	COG0845@1|root,COG0845@2|Bacteria,1UECZ@1239|Firmicutes,25J8Z@186801|Clostridia,25RI9@186804|Peptostreptococcaceae	186801|Clostridia	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_4913_41	1286171.EAL2_c14910	1.23e-78	243.0	COG0325@1|root,COG0325@2|Bacteria,1TRDN@1239|Firmicutes,248R6@186801|Clostridia,25VJK@186806|Eubacteriaceae	186801|Clostridia	S	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis	ylmE	-	-	ko:K06997	-	-	-	-	ko00000	-	-	-	Ala_racemase_N
k141_4913_42	1121324.CLIT_23c02820	1.23e-54	176.0	COG1799@1|root,COG1799@2|Bacteria,1VER3@1239|Firmicutes,24I9Y@186801|Clostridia,25RRB@186804|Peptostreptococcaceae	186801|Clostridia	D	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA	sepF	-	-	ko:K09772	-	-	-	-	ko00000,ko03036	-	-	-	SepF
k141_4913_43	1095747.HMPREF1049_0435	7.33e-06	47.8	COG0762@1|root,COG0762@2|Bacteria,37B79@32066|Fusobacteria	32066|Fusobacteria	S	YGGT family	-	-	-	ko:K02221	-	-	-	-	ko00000,ko02044	-	-	-	YGGT
k141_4913_44	1286171.EAL2_c14880	6.11e-56	187.0	COG2302@1|root,COG2302@2|Bacteria,1U5V2@1239|Firmicutes,24GDV@186801|Clostridia,25WBN@186806|Eubacteriaceae	186801|Clostridia	S	S4 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	S4
k141_4913_45	350688.Clos_1411	1.5e-35	127.0	COG3599@1|root,COG3599@2|Bacteria,1V27M@1239|Firmicutes,24MM3@186801|Clostridia,36FZ8@31979|Clostridiaceae	186801|Clostridia	D	PFAM DivIVA family protein	divIVA	-	-	ko:K04074	-	-	-	-	ko00000,ko03036	-	-	-	DivIVA
k141_4913_46	1151292.QEW_3150	1.59e-87	265.0	COG0775@1|root,COG0775@2|Bacteria,1U7WK@1239|Firmicutes,247U5@186801|Clostridia,25QGK@186804|Peptostreptococcaceae	186801|Clostridia	E	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively	mtnN	-	3.2.2.9	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	M00034,M00609	R00194,R01401	RC00063,RC00318	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
k141_4913_47	1121324.CLIT_23c02870	8.05e-55	176.0	COG0597@1|root,COG0597@2|Bacteria,1VA9R@1239|Firmicutes,24QPP@186801|Clostridia,25RJB@186804|Peptostreptococcaceae	186801|Clostridia	MU	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	lspA	-	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
k141_4913_48	500633.CLOHIR_01118	8.42e-128	373.0	COG0564@1|root,COG0564@2|Bacteria,1TPCM@1239|Firmicutes,247Y2@186801|Clostridia,25QI5@186804|Peptostreptococcaceae	186801|Clostridia	J	Responsible for synthesis of pseudouridine from uracil	rluD	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
k141_4913_49	293826.Amet_2795	8.5e-78	236.0	COG2065@1|root,COG2065@2|Bacteria,1V3GV@1239|Firmicutes,24FQD@186801|Clostridia,36I1Q@31979|Clostridiaceae	186801|Clostridia	F	Belongs to the purine pyrimidine phosphoribosyltransferase family. PyrR subfamily	pyrR	-	2.4.2.9	ko:K02825	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000,ko03000	-	-	iHN637.CLJU_RS05275	Pribosyltran
k141_4913_50	1121324.CLIT_23c02900	5.86e-166	479.0	COG2233@1|root,COG2233@2|Bacteria,1TQKX@1239|Firmicutes,2485Z@186801|Clostridia	186801|Clostridia	F	permease	uraA	-	-	ko:K02824	-	-	-	-	ko00000,ko02000	2.A.40.1.1,2.A.40.1.2	-	-	Xan_ur_permease
k141_4913_51	1391646.AVSU01000001_gene223	6.9e-99	291.0	COG3172@1|root,COG3172@2|Bacteria,1VR87@1239|Firmicutes,25DYE@186801|Clostridia	186801|Clostridia	H	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_28
k141_4913_52	1391646.AVSU01000054_gene1156	1.73e-207	599.0	COG1293@1|root,COG1293@2|Bacteria,1TQ8A@1239|Firmicutes,248RK@186801|Clostridia,25QWG@186804|Peptostreptococcaceae	186801|Clostridia	K	Psort location Cytoplasmic, score	FbpA	-	-	-	-	-	-	-	-	-	-	-	DUF814,FbpA
k141_4913_53	445973.CLOBAR_01452	1.75e-108	323.0	COG1561@1|root,COG1561@2|Bacteria,1TQHJ@1239|Firmicutes,24824@186801|Clostridia,25QT7@186804|Peptostreptococcaceae	186801|Clostridia	S	Domain of unknown function (DUF1732)	yicC	-	-	-	-	-	-	-	-	-	-	-	DUF1732,YicC_N
k141_4913_54	1286171.EAL2_c14790	6.77e-40	134.0	COG2052@1|root,COG2052@2|Bacteria,1VA40@1239|Firmicutes,24MXV@186801|Clostridia,25X81@186806|Eubacteriaceae	186801|Clostridia	S	Domain of unknown function (DUF370)	NPD7_560	-	-	ko:K09777	-	-	-	-	ko00000	-	-	-	DUF370
k141_4913_55	318464.IO99_09705	1.08e-73	228.0	COG0194@1|root,COG0194@2|Bacteria,1TP0M@1239|Firmicutes,24HEX@186801|Clostridia,36EVE@31979|Clostridiaceae	186801|Clostridia	F	Essential for recycling GMP and indirectly, cGMP	gmk	-	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_kin
k141_4913_56	1408422.JHYF01000002_gene2593	2.79e-12	63.2	COG1758@1|root,COG1758@2|Bacteria,1VK74@1239|Firmicutes,24QQK@186801|Clostridia,36MND@31979|Clostridiaceae	186801|Clostridia	K	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits	rpoZ	-	2.7.7.6	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb6
k141_4913_57	272563.CD630_25870	2.64e-185	526.0	COG0452@1|root,COG0452@2|Bacteria,1TPP3@1239|Firmicutes,247J3@186801|Clostridia,25QR8@186804|Peptostreptococcaceae	186801|Clostridia	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	coaBC	-	4.1.1.36,6.3.2.5	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
k141_4913_58	1301100.HG529232_gene7464	1.83e-266	766.0	COG1198@1|root,COG1198@2|Bacteria,1TNYB@1239|Firmicutes,248EI@186801|Clostridia,36DH7@31979|Clostridiaceae	186801|Clostridia	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,ResIII
k141_4913_59	272563.CD630_25850	5.13e-69	212.0	COG0242@1|root,COG0242@2|Bacteria,1V70B@1239|Firmicutes,24JET@186801|Clostridia,25RD5@186804|Peptostreptococcaceae	186801|Clostridia	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
k141_4913_60	545243.BAEV01000106_gene2749	1.86e-99	301.0	COG0223@1|root,COG0223@2|Bacteria,1TQ32@1239|Firmicutes,248ED@186801|Clostridia,36EJW@31979|Clostridiaceae	186801|Clostridia	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	-	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
k141_1885_1	760192.Halhy_6490	4.01e-50	186.0	COG1262@1|root,COG1262@2|Bacteria,4NEUZ@976|Bacteroidetes	976|Bacteroidetes	KLT	PFAM Formylglycine-generating sulfatase enzyme	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2,FGE-sulfatase
k141_3209_3	1348635.BBJY01000008_gene1770	2.64e-89	264.0	COG0782@1|root,COG0782@2|Bacteria,1RCXW@1224|Proteobacteria,1S3UP@1236|Gammaproteobacteria,1XTS8@135623|Vibrionales	135623|Vibrionales	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
k141_4915_1	1232437.KL661966_gene3140	8.57e-59	203.0	COG0542@1|root,COG0542@2|Bacteria,1MURH@1224|Proteobacteria,42M9S@68525|delta/epsilon subdivisions,2WJSZ@28221|Deltaproteobacteria,2MHW3@213118|Desulfobacterales	28221|Deltaproteobacteria	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
k141_4915_2	1265505.ATUG01000001_gene4375	3.83e-09	56.2	COG1946@1|root,COG1946@2|Bacteria,1MV9R@1224|Proteobacteria,42NB1@68525|delta/epsilon subdivisions,2WM1K@28221|Deltaproteobacteria,2MJ0B@213118|Desulfobacterales	28221|Deltaproteobacteria	I	acyl-CoA thioesterase II	tesB	-	-	ko:K10805	ko01040,map01040	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	4HBT_3
k141_1490_1	675813.VIB_002013	2.17e-175	493.0	COG0031@1|root,COG0031@2|Bacteria,1MUBE@1224|Proteobacteria,1RN6J@1236|Gammaproteobacteria,1XUHI@135623|Vibrionales	135623|Vibrionales	E	Pyridoxal-phosphate dependent enzyme	cysM	-	2.5.1.47	ko:K12339	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03132,R03601,R04859	RC00020,RC02814,RC02821,RC02876	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
k141_1490_2	945550.VISI1226_06483	2.98e-145	417.0	COG0697@1|root,COG0697@2|Bacteria,1MZXM@1224|Proteobacteria,1RRID@1236|Gammaproteobacteria,1XTUE@135623|Vibrionales	135623|Vibrionales	EG	of the drug metabolite transporter (DMT) superfamily	-	-	-	-	-	-	-	-	-	-	-	-	EamA
k141_1490_3	425104.Ssed_3188	4.18e-193	548.0	COG2206@1|root,COG3437@1|root,COG2206@2|Bacteria,COG3437@2|Bacteria,1R53C@1224|Proteobacteria,1RZQD@1236|Gammaproteobacteria,2QBJ7@267890|Shewanellaceae	1236|Gammaproteobacteria	T	HDOD domain	-	GO:0003674,GO:0003824,GO:0004112,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008081,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009187,GO:0009214,GO:0009987,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576	-	-	-	-	-	-	-	-	-	-	HD
k141_1490_4	1116375.VEJY3_16801	8.59e-206	583.0	COG4580@1|root,COG4580@2|Bacteria,1Q7QH@1224|Proteobacteria,1RP18@1236|Gammaproteobacteria,1XV8X@135623|Vibrionales	135623|Vibrionales	M	Maltoporin periplasmic N-terminal extension	-	-	-	ko:K16077	-	-	-	-	ko00000,ko02000	1.B.3.1.2	-	-	LamB,Sugarporin_N
k141_2823_1	1219065.VPR01S_27_00150	2.32e-122	353.0	COG0218@1|root,COG0218@2|Bacteria,1MY3Z@1224|Proteobacteria,1RNJP@1236|Gammaproteobacteria,1XTW5@135623|Vibrionales	135623|Vibrionales	D	Necessary for normal cell division and for the maintenance of normal septation	engB	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K03978	-	-	-	-	ko00000,ko03036	-	-	-	MMR_HSR1
k141_2823_2	223926.28805094	2.73e-107	314.0	COG4106@1|root,COG4106@2|Bacteria,1QUFH@1224|Proteobacteria,1T1X5@1236|Gammaproteobacteria,1XTG8@135623|Vibrionales	135623|Vibrionales	S	2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1, 4-benzoquinol methylase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
k141_2823_3	675816.VIA_000106	2.37e-60	193.0	COG3078@1|root,COG3078@2|Bacteria,1N8HM@1224|Proteobacteria,1SDUG@1236|Gammaproteobacteria,1XWXD@135623|Vibrionales	135623|Vibrionales	S	A GTPase-activating protein (GAP) that modifies Der EngA GTPase function. May play a role in ribosome biogenesis	yihI	-	-	ko:K09894	-	-	-	-	ko00000	-	-	-	YihI
k141_2823_4	1280001.BAOA01000051_gene1539	5.74e-55	177.0	2E8BZ@1|root,332QM@2|Bacteria,1NAZY@1224|Proteobacteria,1SD7I@1236|Gammaproteobacteria,1XWXQ@135623|Vibrionales	135623|Vibrionales	S	Protein of unknown function (DUF2489)	HD1705	-	-	-	-	-	-	-	-	-	-	-	DUF2489
k141_2823_5	345073.VC395_0064	2.27e-255	710.0	COG0635@1|root,COG0635@2|Bacteria,1MV1I@1224|Proteobacteria,1RN1Y@1236|Gammaproteobacteria,1XT7M@135623|Vibrionales	135623|Vibrionales	H	Belongs to the anaerobic coproporphyrinogen-III oxidase family	hemN	-	1.3.98.3	ko:K02495	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R06895	RC00884	ko00000,ko00001,ko00002,ko01000	-	-	-	HemN_C,Radical_SAM
k141_2823_6	1116375.VEJY3_15090	7.73e-98	301.0	COG3071@1|root,COG3071@2|Bacteria,1MU7A@1224|Proteobacteria,1RMRG@1236|Gammaproteobacteria,1XT4E@135623|Vibrionales	135623|Vibrionales	H	enzyme of heme biosynthesis	hemY	-	-	ko:K02498	-	-	-	-	ko00000	-	-	-	HemY_N,TPR_16,TPR_19,TPR_2
k141_4916_1	1121878.AUGL01000013_gene2896	1.2e-133	390.0	COG4822@1|root,COG4822@2|Bacteria,1P36Y@1224|Proteobacteria,1RYHX@1236|Gammaproteobacteria	1236|Gammaproteobacteria	H	Catalyzes the insertion of Co(2 ) into sirohydrochlorin	cbiK	-	4.99.1.3	ko:K02190	ko00860,ko01100,map00860,map01100	-	R05807	RC01012	ko00000,ko00001,ko01000	-	-	-	CbiK
k141_3545_1	55601.VANGNB10_cI1004	8.61e-173	496.0	COG2230@1|root,COG2230@2|Bacteria,1MX3U@1224|Proteobacteria,1RNID@1236|Gammaproteobacteria,1XSW4@135623|Vibrionales	135623|Vibrionales	M	COG2230 Cyclopropane fatty acid synthase and related methyltransferases	cfa	-	2.1.1.79	ko:K00574	-	-	-	-	ko00000,ko01000	-	-	-	CMAS
k141_3545_2	223926.28806109	7.26e-92	279.0	COG3496@1|root,COG3496@2|Bacteria,1RC56@1224|Proteobacteria,1RRT8@1236|Gammaproteobacteria,1XW4E@135623|Vibrionales	135623|Vibrionales	S	Protein of unknown function (DUF1365)	-	-	-	ko:K09701	-	-	-	-	ko00000	-	-	-	DUF1365
k141_3545_3	345073.VC395_1135	7.66e-195	553.0	COG2907@1|root,COG2907@2|Bacteria,1MV4Z@1224|Proteobacteria,1RP4P@1236|Gammaproteobacteria,1XSW6@135623|Vibrionales	135623|Vibrionales	S	NAD FAD-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
k141_3545_4	1517681.HW45_23605	1.39e-86	264.0	COG1028@1|root,COG1028@2|Bacteria,1QXDQ@1224|Proteobacteria,1T399@1236|Gammaproteobacteria,1Y34B@135623|Vibrionales	135623|Vibrionales	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
k141_3545_5	243277.VC_1118	3.21e-07	49.7	COG3631@1|root,COG3631@2|Bacteria,1MZS5@1224|Proteobacteria,1S8VN@1236|Gammaproteobacteria,1XXE4@135623|Vibrionales	135623|Vibrionales	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
k141_1214_1	1348635.BBJY01000011_gene1221	8.75e-197	580.0	COG2982@1|root,COG2982@2|Bacteria,1NVUY@1224|Proteobacteria,1RPFM@1236|Gammaproteobacteria,1XSC9@135623|Vibrionales	135623|Vibrionales	M	protein involved in outer membrane biogenesis	asmA	-	-	ko:K07289	-	-	-	-	ko00000	-	-	-	AsmA
k141_1214_2	55601.VANGNB10_cI0915	1.05e-136	388.0	COG0572@1|root,COG0572@2|Bacteria,1MWCH@1224|Proteobacteria,1RNZG@1236|Gammaproteobacteria,1XTHP@135623|Vibrionales	135623|Vibrionales	F	Cytidine monophosphokinase	udk	GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009224,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0043771,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046035,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.7.1.48	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R00513,R00516,R00517,R00962,R00964,R00967,R00968,R00970,R01548,R01549,R01880,R02091,R02096,R02097,R02327,R02332,R02371,R02372,R08232	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PRK
k141_1214_3	345073.VC395_1051	2.57e-158	456.0	COG0489@1|root,COG0489@2|Bacteria,1MU7R@1224|Proteobacteria,1RMJF@1236|Gammaproteobacteria,1XT74@135623|Vibrionales	135623|Vibrionales	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	mrp	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	ParA
k141_2483_1	1219065.VPR01S_04_00420	9.36e-113	330.0	COG1660@1|root,COG1660@2|Bacteria,1MVX6@1224|Proteobacteria,1RNJX@1236|Gammaproteobacteria,1XSBH@135623|Vibrionales	135623|Vibrionales	S	Displays ATPase and GTPase activities	yhbJ	-	-	ko:K06958	-	-	-	-	ko00000,ko03019	-	-	-	ATP_bind_2
k141_2483_2	945550.VISI1226_21851	5.76e-42	139.0	COG1925@1|root,COG1925@2|Bacteria,1N6RM@1224|Proteobacteria,1SCXX@1236|Gammaproteobacteria,1XYBI@135623|Vibrionales	135623|Vibrionales	G	COG1925 Phosphotransferase system, HPr-related proteins	ptsO	GO:0006808,GO:0006810,GO:0008150,GO:0008643,GO:0009401,GO:0050789,GO:0051179,GO:0051234,GO:0065007,GO:0071702	-	ko:K08485	ko02060,map02060	-	-	-	ko00000,ko00001,ko02000	-	-	-	PTS-HPr
k141_2483_3	1116375.VEJY3_13720	2.99e-225	632.0	COG2239@1|root,COG2239@2|Bacteria,1MW24@1224|Proteobacteria,1RNE4@1236|Gammaproteobacteria,1XU5X@135623|Vibrionales	135623|Vibrionales	P	Acts as a magnesium transporter	mgtE	-	-	ko:K06213	-	-	-	-	ko00000,ko02000	1.A.26.1	-	-	CBS,MgtE,MgtE_N
k141_2483_4	29495.EA26_19430	1.75e-253	702.0	COG0312@1|root,COG0312@2|Bacteria,1MUVW@1224|Proteobacteria,1RPJF@1236|Gammaproteobacteria,1XSU9@135623|Vibrionales	135623|Vibrionales	S	Zn-dependent proteases and their inactivated homologs	pmbA	-	-	ko:K03592	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
k141_2945_1	1304885.AUEY01000006_gene739	2.69e-68	221.0	COG1222@1|root,COG1222@2|Bacteria	2|Bacteria	O	protein catabolic process	-	-	3.4.21.53	ko:K04076,ko:K07452	-	-	-	-	ko00000,ko01000,ko01002,ko02048	-	-	-	AAA,AAA_5,Lon_C
k141_2945_2	1123054.KB907703_gene1390	4.79e-58	192.0	COG0679@1|root,COG0679@2|Bacteria,1PHSS@1224|Proteobacteria,1SZPF@1236|Gammaproteobacteria,1X2KG@135613|Chromatiales	135613|Chromatiales	S	Membrane transport protein	-	-	-	-	-	-	-	-	-	-	-	-	Mem_trans
k141_5284_1	177437.HRM2_05320	7.6e-192	544.0	COG2233@1|root,COG2233@2|Bacteria,1MUN9@1224|Proteobacteria,42M4U@68525|delta/epsilon subdivisions,2WJJI@28221|Deltaproteobacteria,2MIMC@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Permease family	uraA	-	-	ko:K02824	-	-	-	-	ko00000,ko02000	2.A.40.1.1,2.A.40.1.2	-	-	Xan_ur_permease
k141_2946_2	211110.gbs1861	4.79e-30	118.0	COG2964@1|root,COG2964@2|Bacteria,1V2VD@1239|Firmicutes,4HHYZ@91061|Bacilli	91061|Bacilli	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	HTH_22,PAS_6
k141_2946_3	585501.HMPREF6123_2184	6.93e-08	53.1	COG3681@1|root,COG3681@2|Bacteria,1TQF5@1239|Firmicutes,2488Q@186801|Clostridia,2PTB3@265975|Oribacterium	186801|Clostridia	S	Belongs to the UPF0597 family	-	-	-	-	-	-	-	-	-	-	-	-	SDH_alpha
k141_5036_1	1537994.JQFW01000022_gene120	1.11e-11	60.1	2EJ6D@1|root,33CXK@2|Bacteria,1NHGW@1224|Proteobacteria,1SGZR@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_2947_1	675806.VII_000721	1.1e-70	221.0	2AXJ2@1|root,31PJ0@2|Bacteria,1QM8P@1224|Proteobacteria,1TJGN@1236|Gammaproteobacteria,1Y17I@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_2948_1	1168034.FH5T_19645	3.32e-78	244.0	28MVB@1|root,2ZB2W@2|Bacteria	2|Bacteria	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_1593_1	1280001.BAOA01000021_gene930	2.15e-62	204.0	COG1270@1|root,COG1270@2|Bacteria,1MURM@1224|Proteobacteria,1S6W4@1236|Gammaproteobacteria,1XSVK@135623|Vibrionales	135623|Vibrionales	H	COG1270 Cobalamin biosynthesis protein CobD CbiB	-	-	6.3.1.10	ko:K02227	ko00860,ko01100,map00860,map01100	M00122	R06529,R07302	RC00090,RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	CobD_Cbib
k141_1593_2	870967.VIS19158_09193	5.18e-119	348.0	COG0614@1|root,COG0614@2|Bacteria,1MWVF@1224|Proteobacteria,1RMV8@1236|Gammaproteobacteria,1XTID@135623|Vibrionales	135623|Vibrionales	P	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC	btuF	-	-	ko:K06858	ko02010,map02010	M00241	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.13	-	-	Peripla_BP_2
k141_1593_4	55601.VANGNB10_cI2157c	2.43e-132	381.0	COG0730@1|root,COG0730@2|Bacteria,1MXNM@1224|Proteobacteria,1RRH4@1236|Gammaproteobacteria,1XSXB@135623|Vibrionales	135623|Vibrionales	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
k141_1593_9	55601.VANGNB10_cI2161c	4.84e-64	198.0	COG0494@1|root,COG0494@2|Bacteria,1RCZM@1224|Proteobacteria,1RS3S@1236|Gammaproteobacteria,1XXA4@135623|Vibrionales	135623|Vibrionales	L	Belongs to the Nudix hydrolase family	mutT	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
k141_1593_11	945543.VIBR0546_20735	7.82e-45	151.0	COG4701@1|root,COG4701@2|Bacteria,1NHRC@1224|Proteobacteria,1S15U@1236|Gammaproteobacteria,1XY04@135623|Vibrionales	135623|Vibrionales	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF721
k141_1593_12	55601.VANGNB10_cI2164c	3.52e-198	551.0	COG0774@1|root,COG0774@2|Bacteria,1MV6T@1224|Proteobacteria,1RQ72@1236|Gammaproteobacteria,1XU76@135623|Vibrionales	135623|Vibrionales	M	Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis	lpxC	GO:0003674,GO:0003824,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008759,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016787,GO:0016810,GO:0016811,GO:0019213,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	3.5.1.108	ko:K02535	ko00540,ko01100,map00540,map01100	M00060	R04587	RC00166,RC00300	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	LpxC
k141_1593_13	243277.VC_2397	2.44e-07	52.4	COG0206@1|root,COG0206@2|Bacteria,1MV2X@1224|Proteobacteria,1RPZS@1236|Gammaproteobacteria,1XTKI@135623|Vibrionales	135623|Vibrionales	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
k141_5037_1	1229205.BUPH_02627	5.94e-57	209.0	COG1061@1|root,COG1061@2|Bacteria,1QCQA@1224|Proteobacteria,2W8BQ@28216|Betaproteobacteria,1K85E@119060|Burkholderiaceae	28216|Betaproteobacteria	L	Type III restriction enzyme, res subunit	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,ResIII
k141_2949_1	536227.CcarbDRAFT_5096	4.33e-31	119.0	COG1309@1|root,COG1309@2|Bacteria,1VJYD@1239|Firmicutes,24SNN@186801|Clostridia	186801|Clostridia	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
k141_2949_2	34506.g7167	2.3e-19	89.7	COG2030@1|root,2QPX4@2759|Eukaryota,39K2N@33154|Opisthokonta,3BD1Y@33208|Metazoa,3CX6W@33213|Bilateria,40AXE@6231|Nematoda,1KU33@119089|Chromadorea,40ZMD@6236|Rhabditida	33208|Metazoa	Q	Belongs to the short-chain dehydrogenases reductases (SDR) family	HSD17B4	GO:0000003,GO:0000038,GO:0002064,GO:0002119,GO:0002164,GO:0003006,GO:0003674,GO:0003824,GO:0003857,GO:0004303,GO:0005102,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0005782,GO:0006066,GO:0006082,GO:0006139,GO:0006163,GO:0006629,GO:0006631,GO:0006635,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0007275,GO:0007548,GO:0007568,GO:0008150,GO:0008152,GO:0008202,GO:0008203,GO:0008209,GO:0008210,GO:0008406,GO:0008584,GO:0009056,GO:0009058,GO:0009062,GO:0009117,GO:0009150,GO:0009259,GO:0009719,GO:0009725,GO:0009791,GO:0009888,GO:0009987,GO:0010033,GO:0010817,GO:0010883,GO:0010888,GO:0014070,GO:0016042,GO:0016054,GO:0016125,GO:0016137,GO:0016138,GO:0016229,GO:0016491,GO:0016508,GO:0016614,GO:0016616,GO:0016829,GO:0016835,GO:0016836,GO:0018812,GO:0019236,GO:0019395,GO:0019637,GO:0019693,GO:0019748,GO:0019752,GO:0022414,GO:0022611,GO:0030154,GO:0030258,GO:0030283,GO:0030855,GO:0031907,GO:0031974,GO:0032501,GO:0032502,GO:0032787,GO:0032879,GO:0033764,GO:0033865,GO:0033875,GO:0033993,GO:0034032,GO:0034440,GO:0034641,GO:0034754,GO:0035337,GO:0035383,GO:0036111,GO:0036112,GO:0040008,GO:0040024,GO:0042221,GO:0042445,GO:0042446,GO:0042493,GO:0042579,GO:0042802,GO:0042803,GO:0042810,GO:0042811,GO:0043053,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044249,GO:0044255,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044438,GO:0044439,GO:0044444,GO:0044446,GO:0044464,GO:0044550,GO:0044594,GO:0045137,GO:0045927,GO:0046395,GO:0046483,GO:0046546,GO:0046661,GO:0046983,GO:0048468,GO:0048513,GO:0048518,GO:0048519,GO:0048545,GO:0048580,GO:0048582,GO:0048608,GO:0048638,GO:0048639,GO:0048731,GO:0048856,GO:0048869,GO:0050789,GO:0050793,GO:0050896,GO:0051094,GO:0051186,GO:0051239,GO:0051240,GO:0051716,GO:0055086,GO:0055114,GO:0055115,GO:0060008,GO:0060009,GO:0060429,GO:0061062,GO:0061063,GO:0061458,GO:0065007,GO:0065008,GO:0070013,GO:0070887,GO:0071310,GO:0071407,GO:0071704,GO:0072329,GO:0072521,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901568,GO:1901575,GO:1901576,GO:1901615,GO:1901657,GO:1901659,GO:1902652,GO:1904069,GO:1904070,GO:1905952,GO:1905953,GO:2000026	1.1.1.35,4.2.1.107,4.2.1.119	ko:K12405	ko00120,ko01100,ko04146,map00120,map01100,map04146	M00104	R04809,R04810,R04812,R04813,R09698	RC00089,RC00770,RC01217	ko00000,ko00001,ko00002,ko01000	-	-	-	MaoC_dehydrat_N,MaoC_dehydratas,SCP2,adh_short
k141_5287_1	545695.TREAZ_0479	8.39e-72	229.0	COG0809@1|root,COG0809@2|Bacteria,2J5HY@203691|Spirochaetes	203691|Spirochaetes	H	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	queA	-	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
k141_5287_2	933262.AXAM01000003_gene2867	5.72e-182	516.0	COG0343@1|root,COG0343@2|Bacteria,1MUCA@1224|Proteobacteria,42M5Y@68525|delta/epsilon subdivisions,2WIMT@28221|Deltaproteobacteria,2MIZI@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	tgt	-	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
k141_5287_3	1167006.UWK_02201	5.13e-83	259.0	COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,42MXG@68525|delta/epsilon subdivisions,2WJ6G@28221|Deltaproteobacteria,2MJ69@213118|Desulfobacterales	28221|Deltaproteobacteria	E	PFAM aminotransferase class I and II	-	-	2.6.1.1	ko:K11358	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
k141_2624_1	876269.ARWA01000001_gene267	8.26e-22	99.4	2C543@1|root,32W3W@2|Bacteria,1N5UD@1224|Proteobacteria,2USST@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_2624_4	796620.VIBC2010_00779	5.35e-108	321.0	2CCV8@1|root,2Z7KX@2|Bacteria,1MY2J@1224|Proteobacteria,1S2KN@1236|Gammaproteobacteria,1Y0QK@135623|Vibrionales	135623|Vibrionales	S	EcsC protein family	-	-	-	-	-	-	-	-	-	-	-	-	EcsC
k141_2624_5	1188252.AJYK01000057_gene333	2.8e-33	116.0	COG0727@1|root,COG0727@2|Bacteria,1MZPF@1224|Proteobacteria,1S8T7@1236|Gammaproteobacteria,1XYQM@135623|Vibrionales	135623|Vibrionales	S	Putative zinc- or iron-chelating domain	-	-	-	-	-	-	-	-	-	-	-	-	CxxCxxCC
k141_2624_6	223926.28809064	4.98e-210	588.0	COG1979@1|root,COG1979@2|Bacteria,1QUBJ@1224|Proteobacteria,1RP7C@1236|Gammaproteobacteria,1XT9D@135623|Vibrionales	135623|Vibrionales	C	oxidoreductases, Fe-dependent alcohol dehydrogenase family	yqhD	-	-	ko:K08325	ko00640,map00640	-	R02528	RC00739	ko00000,ko00001,ko01000	-	-	-	Fe-ADH
k141_2624_8	498761.HM1_0604	5.79e-41	145.0	COG2184@1|root,COG2184@2|Bacteria,1TPUZ@1239|Firmicutes,248XF@186801|Clostridia	186801|Clostridia	D	Protein involved in cell division	fic	-	-	ko:K04095	-	-	-	-	ko00000,ko03036	-	-	-	Fic
k141_2624_9	1348635.BBJY01000007_gene236	2.88e-154	442.0	COG1609@1|root,COG1609@2|Bacteria,1R7GP@1224|Proteobacteria,1RQ7P@1236|Gammaproteobacteria,1XV5G@135623|Vibrionales	135623|Vibrionales	K	Bacterial regulatory proteins, lacI family	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
k141_2624_10	1283284.AZUK01000001_gene160	6.56e-106	311.0	COG4215@1|root,COG4215@2|Bacteria,1MY2N@1224|Proteobacteria,1RNYD@1236|Gammaproteobacteria,1Y47J@135624|Aeromonadales	1236|Gammaproteobacteria	P	ABC transporter	hisQ	GO:0003333,GO:0003674,GO:0005215,GO:0005287,GO:0005290,GO:0005291,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006855,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015174,GO:0015179,GO:0015238,GO:0015318,GO:0015711,GO:0015802,GO:0015807,GO:0015849,GO:0015893,GO:0016020,GO:0022857,GO:0034220,GO:0042221,GO:0042493,GO:0043090,GO:0044464,GO:0045117,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0089709,GO:0089718,GO:0098655,GO:0098656,GO:0098657,GO:0098739,GO:1901474,GO:1902475,GO:1903810,GO:1903825,GO:1905039,GO:1990822	-	ko:K10016,ko:K10024	ko02010,map02010	M00225,M00226,M00235	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3.1,3.A.1.3.11	-	iSbBS512_1146.SbBS512_E2686	BPD_transp_1
k141_2624_11	1283284.AZUK01000001_gene159	4.73e-118	343.0	COG4160@1|root,COG4160@2|Bacteria,1MWI6@1224|Proteobacteria,1RPT1@1236|Gammaproteobacteria,1Y46G@135624|Aeromonadales	1236|Gammaproteobacteria	P	Binding-protein-dependent transport system inner membrane component	hisM	GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0015711,GO:0015849,GO:0016020,GO:0044464,GO:0046942,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944	-	ko:K10015	ko02010,map02010	M00225,M00226	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3.1	-	iAF1260.b2307,iAPECO1_1312.APECO1_4257,iB21_1397.B21_02192,iBWG_1329.BWG_2081,iE2348C_1286.E2348C_2447,iEC55989_1330.EC55989_2551,iECABU_c1320.ECABU_c26390,iECBD_1354.ECBD_1352,iECB_1328.ECB_02232,iECDH10B_1368.ECDH10B_2469,iECDH1ME8569_1439.ECDH1ME8569_2245,iECD_1391.ECD_02232,iECED1_1282.ECED1_2771,iECH74115_1262.ECH74115_3447,iECIAI1_1343.ECIAI1_2383,iECIAI39_1322.ECIAI39_2456,iECNA114_1301.ECNA114_2397,iECO103_1326.ECO103_2771,iECO111_1330.ECO111_3055,iECO26_1355.ECO26_3295,iECOK1_1307.ECOK1_2540,iECP_1309.ECP_2346,iECS88_1305.ECS88_2454,iECSE_1348.ECSE_2616,iECSF_1327.ECSF_2183,iECSP_1301.ECSP_3182,iECW_1372.ECW_m2496,iECs_1301.ECs3191,iEKO11_1354.EKO11_1458,iETEC_1333.ETEC_2443,iEcDH1_1363.EcDH1_1349,iEcE24377_1341.EcE24377A_2601,iEcSMS35_1347.EcSMS35_2463,iEcolC_1368.EcolC_1345,iG2583_1286.G2583_2844,iJO1366.b2307,iJR904.b2307,iLF82_1304.LF82_1007,iNRG857_1313.NRG857_11685,iSDY_1059.SDY_2506,iSFV_1184.SFV_2374,iSF_1195.SF2383,iSFxv_1172.SFxv_2628,iSSON_1240.SSON_2365,iS_1188.S2518,iSbBS512_1146.SbBS512_E2685,iUMN146_1321.UM146_05275,iUMNK88_1353.UMNK88_2858,iUTI89_1310.UTI89_C2591,iWFL_1372.ECW_m2496,iY75_1357.Y75_RS12100,ic_1306.c2849	BPD_transp_1
k141_2624_12	527002.yaldo0001_22780	1.42e-130	377.0	COG4598@1|root,COG4598@2|Bacteria,1QTS2@1224|Proteobacteria,1RQYN@1236|Gammaproteobacteria,41EU5@629|Yersinia	1236|Gammaproteobacteria	E	Histidine ABC transporter ATP-binding protein	hisP	-	3.6.3.21	ko:K10017	ko02010,map02010	M00225,M00226	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.3.1	-	iECIAI39_1322.ECIAI39_2455,iPC815.YPO2777,iYL1228.KPN_02696,iZ_1308.Z3568	ABC_tran
k141_2624_13	640513.Entas_2100	5.14e-87	268.0	COG0583@1|root,COG0583@2|Bacteria,1R509@1224|Proteobacteria,1RSBX@1236|Gammaproteobacteria,3X061@547|Enterobacter	1236|Gammaproteobacteria	K	Transcriptional regulator, LysR	-	-	-	ko:K03566	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_1,LysR_substrate
k141_2624_14	1286093.C266_22700	5.66e-89	272.0	COG0388@1|root,COG0388@2|Bacteria,1MUUB@1224|Proteobacteria,2VIR4@28216|Betaproteobacteria,1K2WY@119060|Burkholderiaceae	28216|Betaproteobacteria	S	PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	opaA	-	3.5.5.1	ko:K01501,ko:K11206	ko00380,ko00460,ko00627,ko00643,ko00910,ko01120,map00380,map00460,map00627,map00643,map00910,map01120	-	R00540,R01887,R03093,R03542,R05591,R07855	RC00315,RC00325,RC00617,RC00959,RC02811	ko00000,ko00001,ko01000	-	-	-	CN_hydrolase
k141_2624_15	104623.Ser39006_03314	4.03e-124	360.0	COG0834@1|root,COG0834@2|Bacteria,1NT2J@1224|Proteobacteria,1RRS2@1236|Gammaproteobacteria,400JD@613|Serratia	1236|Gammaproteobacteria	ET	Belongs to the bacterial solute-binding protein 3 family	-	-	-	ko:K10013	ko02010,map02010	M00225	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3.1	-	-	SBP_bac_3
k141_2624_16	29495.EA26_10565	1.29e-165	469.0	COG4989@1|root,COG4989@2|Bacteria,1MY3G@1224|Proteobacteria,1RRIC@1236|Gammaproteobacteria,1XTIM@135623|Vibrionales	135623|Vibrionales	S	oxidoreductase, aldo keto reductase 2	ydhF	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
k141_2624_17	1136163.M565_ctg4P532	5.86e-169	494.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,1XSE1@135623|Vibrionales	135623|Vibrionales	T	COG2202 FOG PAS PAC domain	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal,PAS_3
k141_2624_18	1298865.H978DRAFT_0863	4.07e-187	548.0	28I8G@1|root,2Z8BA@2|Bacteria,1MWYF@1224|Proteobacteria,1RTN9@1236|Gammaproteobacteria,4656S@72275|Alteromonadaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	zinc_ribbon_2
k141_1597_1	5180.EDO03824	1.59e-10	62.0	COG0642@1|root,KOG0519@2759|Eukaryota,391YN@33154|Opisthokonta,3NV7C@4751|Fungi,3QPHU@4890|Ascomycota,20WGV@147548|Leotiomycetes	4751|Fungi	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
k141_1597_2	398512.JQKC01000012_gene189	1.78e-29	117.0	COG1385@1|root,COG1385@2|Bacteria,1V1CT@1239|Firmicutes,249VK@186801|Clostridia,3WIFN@541000|Ruminococcaceae	186801|Clostridia	J	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit	rsmE	-	2.1.1.193	ko:K09761	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_RNA
k141_5288_1	644282.Deba_1621	6.68e-77	259.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,439X1@68525|delta/epsilon subdivisions,2WJBG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	NT	methyl-accepting chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	DUF3365,HAMP,MCPsignal
k141_2626_2	179408.Osc7112_4472	6.41e-07	55.1	COG0642@1|root,COG0745@1|root,COG0784@1|root,COG2202@1|root,COG2203@1|root,COG0745@2|Bacteria,COG0784@2|Bacteria,COG2202@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,1G09B@1117|Cyanobacteria,1H9EM@1150|Oscillatoriales	1117|Cyanobacteria	T	Signal Transduction Histidine Kinase	-	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	GAF,GAF_2,HAMP,HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Response_reg,dCache_1
k141_2626_3	1121456.ATVA01000016_gene2087	1.27e-55	182.0	COG0425@1|root,COG0425@2|Bacteria,1N08X@1224|Proteobacteria,42RUG@68525|delta/epsilon subdivisions,2WNNK@28221|Deltaproteobacteria,2MB1E@213115|Desulfovibrionales	28221|Deltaproteobacteria	O	Belongs to the sulfur carrier protein TusA family	yedF	-	-	-	-	-	-	-	-	-	-	-	DrsE,TusA
k141_3291_1	223926.28807948	0.0	2485.0	COG0085@1|root,COG0085@2|Bacteria,1MUC4@1224|Proteobacteria,1RMK0@1236|Gammaproteobacteria,1XUTX@135623|Vibrionales	135623|Vibrionales	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	GO:0000428,GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030880,GO:0032774,GO:0032991,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
k141_3291_3	243277.VC_0330	7.29e-67	207.0	COG3160@1|root,COG3160@2|Bacteria,1RHBB@1224|Proteobacteria,1S420@1236|Gammaproteobacteria,1XWY4@135623|Vibrionales	135623|Vibrionales	K	Belongs to the Rsd AlgQ family	rsd	-	-	ko:K07740	-	-	-	-	ko00000	-	-	-	Rsd_AlgQ
k141_3291_4	1348635.BBJY01000030_gene2126	5.93e-141	403.0	COG2816@1|root,COG2816@2|Bacteria,1QGCX@1224|Proteobacteria,1RP0Y@1236|Gammaproteobacteria,1XV54@135623|Vibrionales	135623|Vibrionales	L	COG2816 NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding	nudC	GO:0003674,GO:0003824,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360	3.6.1.22	ko:K03426	ko00760,ko01100,ko04146,map00760,map01100,map04146	-	R00103,R03004,R11104	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX,zf-NADH-PPase
k141_3291_5	1188252.AJYK01000120_gene890	9.06e-223	618.0	COG0407@1|root,COG0407@2|Bacteria,1MUG1@1224|Proteobacteria,1RMDH@1236|Gammaproteobacteria,1XTP5@135623|Vibrionales	135623|Vibrionales	H	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III	hemE	GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006536,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009064,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019353,GO:0019438,GO:0019752,GO:0033013,GO:0033014,GO:0033526,GO:0034641,GO:0042168,GO:0042440,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
k141_3291_6	1051646.VITU9109_13562	1.31e-114	344.0	COG4942@1|root,COG4942@2|Bacteria,1MY3E@1224|Proteobacteria,1RPQP@1236|Gammaproteobacteria,1XSXQ@135623|Vibrionales	135623|Vibrionales	D	COG4942 Membrane-bound metallopeptidase	envC	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
k141_4336_90	29495.EA26_20125	0.0	1087.0	COG1053@1|root,COG1053@2|Bacteria,1MU5M@1224|Proteobacteria,1RMU2@1236|Gammaproteobacteria,1XSH4@135623|Vibrionales	135623|Vibrionales	C	fumarate reductase, flavoprotein subunit	frdA	-	1.3.5.4	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	M00009,M00011,M00150,M00173	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
k141_4336_91	223926.28807867	3.38e-166	466.0	COG0479@1|root,COG0479@2|Bacteria,1MVHS@1224|Proteobacteria,1RNWR@1236|Gammaproteobacteria,1XTYJ@135623|Vibrionales	135623|Vibrionales	C	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family	frdB	-	1.3.5.4	ko:K00245	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	M00009,M00011,M00150,M00173	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_3,Fer4_8
k141_4336_92	675813.VIB_000487	4.65e-71	215.0	COG3029@1|root,COG3029@2|Bacteria,1MZ4C@1224|Proteobacteria,1SC0P@1236|Gammaproteobacteria,1XXFQ@135623|Vibrionales	135623|Vibrionales	C	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane	frdC	GO:0000104,GO:0003674,GO:0003824,GO:0006091,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015980,GO:0016491,GO:0016627,GO:0044237,GO:0045333,GO:0055114	-	ko:K00246	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	M00009,M00011,M00150,M00173	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	Fumarate_red_C
k141_4336_93	55601.VANGNB10_cI2409	7.16e-75	224.0	COG3080@1|root,COG3080@2|Bacteria,1RDZD@1224|Proteobacteria,1S3W5@1236|Gammaproteobacteria,1XXAW@135623|Vibrionales	135623|Vibrionales	C	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane	frdD	GO:0000104,GO:0003674,GO:0003824,GO:0006091,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015980,GO:0016491,GO:0016627,GO:0044237,GO:0045333,GO:0055114	-	ko:K00247	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	M00009,M00011,M00150,M00173	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	Fumarate_red_D
k141_4336_95	675814.VIC_000062	2.23e-178	504.0	COG1509@1|root,COG1509@2|Bacteria,1MUPJ@1224|Proteobacteria,1RM84@1236|Gammaproteobacteria,1XUU0@135623|Vibrionales	135623|Vibrionales	C	Lysine 2,3-aminomutase	yjeK	-	-	ko:K19810	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Fer4_12,Fer4_14,Radical_SAM
k141_4336_96	345073.VC395_2777	0.0	926.0	COG0459@1|root,COG0459@2|Bacteria,1MURR@1224|Proteobacteria,1RMTB@1236|Gammaproteobacteria,1XSXK@135623|Vibrionales	135623|Vibrionales	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
k141_4336_98	1191299.AJYX01000051_gene1261	2.69e-91	273.0	COG2345@1|root,COG2345@2|Bacteria,1RDXT@1224|Proteobacteria,1S4DW@1236|Gammaproteobacteria,1XTKY@135623|Vibrionales	135623|Vibrionales	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_11,HTH_24,HTH_DeoR
k141_4336_99	1187848.AJYQ01000004_gene210	1.27e-20	87.0	2EM8V@1|root,33EY0@2|Bacteria,1NBBF@1224|Proteobacteria,1SDDM@1236|Gammaproteobacteria,1XYUC@135623|Vibrionales	135623|Vibrionales	S	Protein of unknown function (DUF3135)	VV3022	-	-	-	-	-	-	-	-	-	-	-	DUF3135
k141_4336_100	1188252.AJYK01000068_gene207	4.13e-32	116.0	COG3232@1|root,COG3232@2|Bacteria,1N7P5@1224|Proteobacteria,1S5D7@1236|Gammaproteobacteria,1XXDP@135623|Vibrionales	135623|Vibrionales	G	5-carboxymethyl-2-hydroxymuconate isomerase	hpcD	-	5.3.3.10	ko:K01826	ko00350,ko01120,ko01220,map00350,map01120,map01220	M00533	R04379,R04482	RC01141,RC01162	ko00000,ko00001,ko00002,ko01000	-	-	-	CHMI
k141_4336_102	945543.VIBR0546_08359	7.81e-122	363.0	COG0534@1|root,COG0534@2|Bacteria,1MVRV@1224|Proteobacteria,1RRDQ@1236|Gammaproteobacteria,1XTD2@135623|Vibrionales	135623|Vibrionales	V	Na driven multidrug efflux pump	-	-	-	-	-	-	-	-	-	-	-	-	MatE
k141_5097_1	1123075.AUDP01000031_gene2118	2.97e-36	147.0	COG5001@1|root,COG5001@2|Bacteria,1TP8V@1239|Firmicutes,247PX@186801|Clostridia,3WST1@541000|Ruminococcaceae	186801|Clostridia	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,dCache_1
k141_5293_1	945543.VIBR0546_09277	5.81e-184	515.0	COG0408@1|root,COG0408@2|Bacteria,1MWMF@1224|Proteobacteria,1RMM8@1236|Gammaproteobacteria,1XT68@135623|Vibrionales	135623|Vibrionales	H	Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX	hemF	GO:0003674,GO:0003824,GO:0004109,GO:0005488,GO:0005515,GO:0006725,GO:0006778,GO:0006779,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016627,GO:0016634,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042802,GO:0042803,GO:0044237,GO:0044249,GO:0044271,GO:0046483,GO:0046983,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	1.3.3.3	ko:K00228	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03220	RC00884	ko00000,ko00001,ko00002,ko01000	-	-	-	Coprogen_oxidas
k141_5293_2	945550.VISI1226_17240	1.39e-93	277.0	COG0009@1|root,COG0009@2|Bacteria,1MVPM@1224|Proteobacteria,1S610@1236|Gammaproteobacteria,1XV14@135623|Vibrionales	135623|Vibrionales	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-) CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate	tsaC	GO:0000049,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006450,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0065007,GO:0065008,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	Sua5_yciO_yrdC
k141_5293_5	1219065.VPR01S_22_00080	7.68e-62	197.0	COG0551@1|root,COG0551@2|Bacteria,1MX2E@1224|Proteobacteria,1RQ85@1236|Gammaproteobacteria,1XUJR@135623|Vibrionales	135623|Vibrionales	L	COG0551 Zn-finger domain associated with topoisomerase type I	yrdD	-	-	ko:K07479	-	-	-	-	ko00000	-	-	-	zf-C4_Topoisom
k141_5293_7	55601.VANGNB10_cI0058	1.12e-148	433.0	COG0758@1|root,COG0758@2|Bacteria,1MVF6@1224|Proteobacteria,1RPJE@1236|Gammaproteobacteria,1XSI4@135623|Vibrionales	135623|Vibrionales	LU	Rossmann fold nucleotide-binding protein involved in DNA uptake	smf	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A
k141_5293_8	55601.VANGNB10_cI0056c	1.13e-94	278.0	COG0242@1|root,COG0242@2|Bacteria,1RA2P@1224|Proteobacteria,1S247@1236|Gammaproteobacteria,1XSD0@135623|Vibrionales	135623|Vibrionales	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def	GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008463,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
k141_5293_9	1348635.BBJY01000022_gene1907	4.46e-191	534.0	COG0223@1|root,COG0223@2|Bacteria,1MU4Q@1224|Proteobacteria,1RP1T@1236|Gammaproteobacteria,1XTX0@135623|Vibrionales	135623|Vibrionales	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	GO:0003674,GO:0003824,GO:0004479,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006418,GO:0006431,GO:0006464,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019752,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
k141_5293_10	674977.VMC_25010	3.81e-237	660.0	COG0144@1|root,COG0781@1|root,COG0144@2|Bacteria,COG0781@2|Bacteria,1MWPE@1224|Proteobacteria,1RN8X@1236|Gammaproteobacteria,1XUH8@135623|Vibrionales	135623|Vibrionales	J	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA	rsmB	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.176	ko:K03500	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F,NusB
k141_5293_14	675813.VIB_003043	1.03e-191	537.0	COG2334@1|root,COG2334@2|Bacteria,1MU2Q@1224|Proteobacteria,1RNHI@1236|Gammaproteobacteria,1XU7N@135623|Vibrionales	135623|Vibrionales	F	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response	srkA	-	-	-	-	-	-	-	-	-	-	-	APH
k141_5293_15	1219065.VPR01S_01_03030	1.27e-65	207.0	COG1651@1|root,COG1651@2|Bacteria,1RGWH@1224|Proteobacteria,1S5WA@1236|Gammaproteobacteria,1XV51@135623|Vibrionales	135623|Vibrionales	O	Thiol disulfide interchange protein	-	-	-	ko:K03673	ko01503,map01503	M00728	-	-	ko00000,ko00001,ko00002,ko03110	-	-	-	DSBA
k141_5293_16	1238450.VIBNISOn1_1410012	1.91e-161	457.0	COG0204@1|root,COG0204@2|Bacteria,1MVWG@1224|Proteobacteria,1RR21@1236|Gammaproteobacteria,1XTJU@135623|Vibrionales	135623|Vibrionales	I	1-acyl-sn-glycerol-3-phosphate acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
k141_5293_17	675815.VOA_000026	7.82e-291	803.0	COG0606@1|root,COG0606@2|Bacteria,1MU4R@1224|Proteobacteria,1RMB9@1236|Gammaproteobacteria,1XTCR@135623|Vibrionales	135623|Vibrionales	O	ATPase with chaperone activity	comM	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
k141_5293_18	675815.VOA_000027	0.0	945.0	COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,1RMQQ@1236|Gammaproteobacteria,1XU32@135623|Vibrionales	135623|Vibrionales	H	COG0028 Thiamine pyrophosphate-requiring enzymes acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase	ilvG	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
k141_5293_19	55601.VANGNB10_cI0027c	9.85e-53	166.0	COG3978@1|root,COG3978@2|Bacteria,1MZ9W@1224|Proteobacteria,1S8VQ@1236|Gammaproteobacteria,1XXVG@135623|Vibrionales	135623|Vibrionales	S	COG3978 Acetolactate synthase (isozyme II), small (regulatory) subunit	ilvM	-	2.2.1.6	ko:K11258	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT_5
k141_5293_20	243277.VC_0029	4.11e-194	542.0	COG0115@1|root,COG0115@2|Bacteria,1MVB0@1224|Proteobacteria,1RP6Z@1236|Gammaproteobacteria,1XUBQ@135623|Vibrionales	135623|Vibrionales	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
k141_5293_21	1116375.VEJY3_15410	0.0	1022.0	COG0129@1|root,COG0129@2|Bacteria,1MUTQ@1224|Proteobacteria,1RMP2@1236|Gammaproteobacteria,1XSW5@135623|Vibrionales	135623|Vibrionales	H	Belongs to the IlvD Edd family	ilvD	GO:0003674,GO:0003824,GO:0004160,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
k141_5293_23	945550.VISI1226_17090	3.26e-35	121.0	COG0425@1|root,COG0425@2|Bacteria,1MZA5@1224|Proteobacteria,1S8TC@1236|Gammaproteobacteria,1XYAC@135623|Vibrionales	135623|Vibrionales	O	Sulfur carrier protein which probably makes part of a sulfur-relay system	tusA	GO:0008150,GO:0009987,GO:0019725,GO:0042592,GO:0048878,GO:0055082,GO:0065007,GO:0065008	-	ko:K04085	ko04122,map04122	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	TusA
k141_5293_24	870967.VIS19158_22257	3.1e-35	122.0	2AWHF@1|root,31NDZ@2|Bacteria,1QK51@1224|Proteobacteria,1TI85@1236|Gammaproteobacteria,1XYM6@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_5293_25	1219077.VAZ01S_034_00100	1.81e-99	292.0	COG2119@1|root,COG2119@2|Bacteria,1RDDV@1224|Proteobacteria,1S3QT@1236|Gammaproteobacteria,1XSNJ@135623|Vibrionales	135623|Vibrionales	S	Uncharacterized protein family UPF0016	-	-	-	-	-	-	-	-	-	-	-	-	UPF0016
k141_5293_26	55601.VANGNB10_cI0018c	1.23e-220	608.0	COG0752@1|root,COG0752@2|Bacteria,1MVCJ@1224|Proteobacteria,1RMYI@1236|Gammaproteobacteria,1XT6R@135623|Vibrionales	135623|Vibrionales	J	glycyl-trna synthetase alpha subunit	glyQ	-	6.1.1.14	ko:K01878	ko00970,map00970	M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2e
k141_5293_28	1116375.VEJY3_00085	3.64e-07	51.2	COG3977@1|root,COG3977@2|Bacteria,1MVRW@1224|Proteobacteria,1RNK1@1236|Gammaproteobacteria,1XUEC@135623|Vibrionales	135623|Vibrionales	E	Valine--pyruvate aminotransferase	avtA	-	2.6.1.66	ko:K00835	ko00290,ko01100,ko01110,ko01130,map00290,map01100,map01110,map01130	-	R01215	RC00008,RC00036	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
k141_5293_31	675813.VIB_003020	2.07e-204	572.0	COG1195@1|root,COG1195@2|Bacteria,1MX8N@1224|Proteobacteria,1RN5P@1236|Gammaproteobacteria,1XTHH@135623|Vibrionales	135623|Vibrionales	L	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP	recF	GO:0000731,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576	-	ko:K03629	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	SMC_N
k141_5293_32	675815.VOA_000046	1.83e-197	555.0	COG0592@1|root,COG0592@2|Bacteria,1MVD9@1224|Proteobacteria,1RMNP@1236|Gammaproteobacteria,1XSM8@135623|Vibrionales	135623|Vibrionales	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	dnaN	GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032991,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
k141_5293_36	1051646.VITU9109_19994	1.71e-287	797.0	COG0706@1|root,COG0706@2|Bacteria,1MV5M@1224|Proteobacteria,1RMH1@1236|Gammaproteobacteria,1XU5N@135623|Vibrionales	135623|Vibrionales	U	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins	yidC	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP,YidC_periplas
k141_5293_38	1348635.BBJY01000022_gene1948	1.97e-74	225.0	COG0369@1|root,COG0369@2|Bacteria,1QUGM@1224|Proteobacteria,1T1YC@1236|Gammaproteobacteria,1XWYJ@135623|Vibrionales	135623|Vibrionales	P	COG0716 Flavodoxins	mioC	GO:0003674,GO:0003824,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016491,GO:0022900,GO:0044237,GO:0055114	-	ko:K06205	-	-	-	-	ko00000	-	-	-	Flavodoxin_1
k141_5293_40	243277.VC_2775	0.0	1061.0	COG0445@1|root,COG0445@2|Bacteria,1MU6F@1224|Proteobacteria,1RMM1@1236|Gammaproteobacteria,1XT9G@135623|Vibrionales	135623|Vibrionales	D	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34	gidA	GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363	-	ko:K03495	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko03016,ko03036	-	-	-	GIDA,GIDA_assoc
k141_5293_43	1348635.BBJY01000022_gene1952	1.45e-133	387.0	COG1475@1|root,COG1475@2|Bacteria,1MW2E@1224|Proteobacteria,1RN65@1236|Gammaproteobacteria,1XUPW@135623|Vibrionales	135623|Vibrionales	K	Belongs to the ParB family	parB	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
k141_5293_45	314282.PCNPT3_00190	6.19e-140	400.0	COG0356@1|root,COG0356@2|Bacteria,1MV87@1224|Proteobacteria,1RPHK@1236|Gammaproteobacteria,2QHM8@267894|Psychromonadaceae	1236|Gammaproteobacteria	C	it plays a direct role in the translocation of protons across the membrane	atpB	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042777,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	iAPECO1_1312.APECO1_2725,iE2348C_1286.E2348C_4048,iEC042_1314.EC042_4125,iECABU_c1320.ECABU_c42230,iECED1_1282.ECED1_4428,iECIAI39_1322.ECIAI39_4342,iECNA114_1301.ECNA114_3887,iECOK1_1307.ECOK1_4187,iECP_1309.ECP_3937,iECS88_1305.ECS88_4160,iECSF_1327.ECSF_3586,iECUMN_1333.ECUMN_4268,iEcSMS35_1347.EcSMS35_4106,iLF82_1304.LF82_0192,iNRG857_1313.NRG857_18615,iUMN146_1321.UM146_18880,iUMNK88_1353.UMNK88_4550,iUTI89_1310.UTI89_C4293,ic_1306.c4666	ATP-synt_A
k141_5293_53	1219076.N646_2167	1.25e-257	714.0	COG1207@1|root,COG1207@2|Bacteria,1MUPH@1224|Proteobacteria,1RNKE@1236|Gammaproteobacteria,1XTBG@135623|Vibrionales	135623|Vibrionales	M	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain	glmU	GO:0000270,GO:0000271,GO:0003674,GO:0003824,GO:0003977,GO:0005975,GO:0005976,GO:0006022,GO:0006023,GO:0006024,GO:0006629,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009252,GO:0009273,GO:0009987,GO:0016051,GO:0016740,GO:0016772,GO:0016779,GO:0030203,GO:0033692,GO:0034637,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0070569,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:1903509	2.3.1.157,2.7.7.23	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00362	R00416,R05332	RC00002,RC00004,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transf_3
k141_5293_54	29495.EA26_00545	1.47e-101	299.0	COG1739@1|root,COG1739@2|Bacteria,1NFJC@1224|Proteobacteria,1RPBF@1236|Gammaproteobacteria,1XTYV@135623|Vibrionales	135623|Vibrionales	S	Domain of unknown function (DUF1949)	yigZ	-	-	-	-	-	-	-	-	-	-	-	DUF1949,UPF0029
k141_5293_55	243277.VC_2755	3.28e-68	212.0	COG4635@1|root,COG4635@2|Bacteria,1RAH2@1224|Proteobacteria,1S372@1236|Gammaproteobacteria,1XSWA@135623|Vibrionales	135623|Vibrionales	CH	protoporphyrinogen oxidase	hemG	-	1.3.5.3	ko:K00230	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R09489	RC00885	ko00000,ko00001,ko00002,ko01000	-	-	-	Flavodoxin_5
k141_2671_3	1348635.BBJY01000029_gene2057	5.84e-115	340.0	COG2017@1|root,COG2017@2|Bacteria,1MVUY@1224|Proteobacteria,1RQ29@1236|Gammaproteobacteria,1Y214@135623|Vibrionales	135623|Vibrionales	G	Domain of unknown function (DUF4432)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4432
k141_2672_1	1230342.CTM_03830	8.81e-23	103.0	COG1075@1|root,COG1075@2|Bacteria,1UC87@1239|Firmicutes,24BRI@186801|Clostridia,36GB7@31979|Clostridiaceae	186801|Clostridia	S	acetyltransferases and hydrolases with the alpha beta hydrolase fold	-	-	3.1.1.3	ko:K01046	ko00561,ko01100,map00561,map01100	M00098	R02250,R02687	RC00020,RC00037,RC00041,RC00094	ko00000,ko00001,ko00002,ko01000	-	-	-	-
k141_4388_1	675815.VOA_001698	1.3e-222	627.0	COG0446@1|root,COG0607@1|root,COG0446@2|Bacteria,COG0607@2|Bacteria,1NR3M@1224|Proteobacteria,1T1WT@1236|Gammaproteobacteria,1XSS8@135623|Vibrionales	135623|Vibrionales	P	NAD(FAD)-dependent dehydrogenases	cdr	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Pyr_redox_dim,Rhodanese
k141_4388_2	1219077.VAZ01S_049_00260	4.06e-130	384.0	COG0840@1|root,COG0840@2|Bacteria,1R5W9@1224|Proteobacteria,1RZUT@1236|Gammaproteobacteria,1XU6H@135623|Vibrionales	135623|Vibrionales	NT	COG0840 Methyl-accepting chemotaxis protein	-	-	-	-	-	-	-	-	-	-	-	-	CZB,MCPsignal
k141_4388_3	675815.VOA_003461	1.75e-254	704.0	COG0446@1|root,COG0446@2|Bacteria,1QUQF@1224|Proteobacteria,1RP1H@1236|Gammaproteobacteria,1Y0D6@135623|Vibrionales	135623|Vibrionales	S	Pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2
k141_4388_4	1122599.AUGR01000015_gene2694	2.11e-135	392.0	COG4589@1|root,COG4589@2|Bacteria,1MX58@1224|Proteobacteria,1RRAG@1236|Gammaproteobacteria,1XNNH@135619|Oceanospirillales	135619|Oceanospirillales	S	Cytidylyltransferase family	-	-	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
k141_4388_7	674977.VMC_38440	7.69e-76	231.0	28I53@1|root,2Z88I@2|Bacteria,1NE5N@1224|Proteobacteria,1RP35@1236|Gammaproteobacteria,1Y03I@135623|Vibrionales	135623|Vibrionales	S	Protein of unknown function (DUF3750)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3750
k141_4388_8	1348635.BBJY01000010_gene1401	1.26e-145	419.0	COG2199@1|root,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,1RMA9@1236|Gammaproteobacteria,1XTUI@135623|Vibrionales	135623|Vibrionales	T	COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Response_reg
k141_4388_10	945550.VISI1226_01750	1.21e-53	173.0	2CB6X@1|root,2ZTSF@2|Bacteria,1P8T9@1224|Proteobacteria,1STHQ@1236|Gammaproteobacteria,1XX1M@135623|Vibrionales	135623|Vibrionales	S	Protein of unknown function (DUF3069)	VPA0928	-	-	-	-	-	-	-	-	-	-	-	DUF3069
k141_4388_11	1348635.BBJY01000005_gene3301	1.29e-246	691.0	COG3845@1|root,COG3845@2|Bacteria,1NT0H@1224|Proteobacteria,1T1GV@1236|Gammaproteobacteria,1XVTA@135623|Vibrionales	1236|Gammaproteobacteria	S	ATPases associated with a variety of cellular activities	-	-	3.6.3.17	ko:K02056	-	M00221	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.2	-	-	ABC_tran
k141_4388_12	1348635.BBJY01000005_gene3302	6.84e-164	470.0	COG4603@1|root,COG4603@2|Bacteria,1MX6V@1224|Proteobacteria,1RS4S@1236|Gammaproteobacteria,1XWKM@135623|Vibrionales	1236|Gammaproteobacteria	S	Branched-chain amino acid transport system / permease component	IV02_22040	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
k141_4388_13	1348635.BBJY01000005_gene3303	4.41e-151	432.0	COG1079@1|root,COG1079@2|Bacteria,1MVDQ@1224|Proteobacteria,1RR75@1236|Gammaproteobacteria,1XU9Y@135623|Vibrionales	1236|Gammaproteobacteria	S	Branched-chain amino acid transport system / permease component	IV02_22045	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
k141_4388_14	1348635.BBJY01000005_gene3304	6.26e-195	547.0	COG1744@1|root,COG1744@2|Bacteria,1MWTM@1224|Proteobacteria,1RYCX@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	ABC-type transport system, periplasmic component surface lipoprotein	-	-	-	ko:K02058	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	Bmp
k141_4388_15	1219076.N646_3301	1.11e-51	173.0	COG3110@1|root,COG3110@2|Bacteria,1RK33@1224|Proteobacteria,1RZRX@1236|Gammaproteobacteria,1XWDI@135623|Vibrionales	135623|Vibrionales	S	Belongs to the UPF0319 family	SO3571	-	-	ko:K09909	-	-	-	-	ko00000	-	-	-	DUF2057
k141_4388_16	590409.Dd586_1727	1.22e-43	150.0	COG1670@1|root,COG1670@2|Bacteria,1N36Q@1224|Proteobacteria,1S9V1@1236|Gammaproteobacteria,2JC6E@204037|Dickeya	1236|Gammaproteobacteria	J	PFAM GCN5-related N-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
k141_4388_17	1454202.PPBDW_90122___1	8.22e-34	120.0	2DMIM@1|root,32RUN@2|Bacteria,1MZ56@1224|Proteobacteria,1S9Z2@1236|Gammaproteobacteria,1XYIF@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_4388_18	945550.VISI1226_01575	8.77e-17	73.6	2AWQ5@1|root,31NM3@2|Bacteria,1QKBQ@1224|Proteobacteria,1TIF5@1236|Gammaproteobacteria,1XZ0U@135623|Vibrionales	135623|Vibrionales	-	-	VPA0857	-	-	-	-	-	-	-	-	-	-	-	-
k141_4388_21	1565129.JSFF01000014_gene427	5.07e-115	352.0	COG2199@1|root,COG3452@1|root,COG2199@2|Bacteria,COG3452@2|Bacteria,1R4NG@1224|Proteobacteria,1S0XZ@1236|Gammaproteobacteria,2QA77@267890|Shewanellaceae	1236|Gammaproteobacteria	T	CHASE	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,GGDEF,PAS_4
k141_4388_22	1348635.BBJY01000003_gene3887	0.0	917.0	COG0281@1|root,COG0281@2|Bacteria,1MU0A@1224|Proteobacteria,1RQ11@1236|Gammaproteobacteria,1XTTY@135623|Vibrionales	1236|Gammaproteobacteria	C	malic enzyme	maeA	GO:0003674,GO:0003824,GO:0004470,GO:0004471,GO:0004473,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006094,GO:0006108,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016051,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0019318,GO:0019319,GO:0019752,GO:0032787,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0055114,GO:0071704,GO:1901576	1.1.1.38,1.1.1.40	ko:K00027,ko:K00029	ko00620,ko00710,ko01100,ko01120,ko01200,ko02020,map00620,map00710,map01100,map01120,map01200,map02020	M00169,M00172	R00214,R00216	RC00105	ko00000,ko00001,ko00002,ko01000	-	-	iSbBS512_1146.SbBS512_E1742	Malic_M,malic
k141_4389_1	546414.Deide_14600	5.62e-23	105.0	COG0683@1|root,COG0683@2|Bacteria,1WI02@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	ABC-type branched-chain amino acid transport	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
k141_2673_1	521000.PROVRETT_08101	1.58e-162	459.0	COG3718@1|root,COG3718@2|Bacteria,1MWGD@1224|Proteobacteria,1RQC9@1236|Gammaproteobacteria,3Z8T6@586|Providencia	1236|Gammaproteobacteria	G	enzyme involved in inositol metabolism	iolB	-	5.3.1.30	ko:K03337	ko00562,ko01100,ko01120,map00562,map01100,map01120	-	R08503	RC00541	ko00000,ko00001,ko01000	-	-	-	KduI
k141_4390_1	1187848.AJYQ01000076_gene1681	3.9e-91	281.0	COG3287@1|root,COG3287@2|Bacteria,1R825@1224|Proteobacteria,1S25E@1236|Gammaproteobacteria,1Y2U6@135623|Vibrionales	135623|Vibrionales	S	FIST N domain	-	-	-	-	-	-	-	-	-	-	-	-	FIST,FIST_C
k141_4391_1	926692.AZYG01000094_gene2000	4.54e-62	204.0	COG2200@1|root,COG2200@2|Bacteria,1UY3J@1239|Firmicutes,25B36@186801|Clostridia	186801|Clostridia	T	EAL domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL
k141_2676_1	1232437.KL661966_gene3139	1.63e-62	194.0	COG2944@1|root,COG2944@2|Bacteria,1N66H@1224|Proteobacteria,42UQW@68525|delta/epsilon subdivisions,2WQQF@28221|Deltaproteobacteria,2MKNP@213118|Desulfobacterales	28221|Deltaproteobacteria	K	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
k141_2676_2	1232437.KL661966_gene3138	7.13e-92	278.0	COG1045@1|root,COG1045@2|Bacteria,1MVFX@1224|Proteobacteria,42MND@68525|delta/epsilon subdivisions,2WJC3@28221|Deltaproteobacteria,2MIG5@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Bacterial transferase hexapeptide (six repeats)	cysE	-	2.3.1.30	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	M00021	R00586	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,SATase_N
k141_2677_1	675816.VIA_003451	1.14e-126	379.0	COG1199@1|root,COG1199@2|Bacteria,1MVCU@1224|Proteobacteria,1RMNX@1236|Gammaproteobacteria,1XSPF@135623|Vibrionales	135623|Vibrionales	KL	ATP-dependent helicase	yoaA	-	3.6.4.12	ko:K03722	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DEAD_2,Helicase_C_2,ResIII
k141_2680_1	1304888.ATWF01000002_gene339	4.66e-35	126.0	COG2834@1|root,COG2834@2|Bacteria,2GG12@200930|Deferribacteres	200930|Deferribacteres	M	Outer membrane lipoprotein-sorting protein	-	-	-	-	-	-	-	-	-	-	-	-	LolA_like
k141_2680_2	1304888.ATWF01000002_gene338	2.83e-58	196.0	COG3103@1|root,COG3103@2|Bacteria	2|Bacteria	T	Sh3 type 3 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF1302
k141_2681_1	1136163.M565_ctg4P532	2.28e-08	55.1	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,1XSE1@135623|Vibrionales	135623|Vibrionales	T	COG2202 FOG PAS PAC domain	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal,PAS_3
k141_2681_2	1120963.KB894496_gene2675	1.89e-14	72.4	2DS85@1|root,33EYM@2|Bacteria,1NJQN@1224|Proteobacteria,1SHH9@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_992_2	55601.VANGNB10_cII0083	0.0	1552.0	COG3523@1|root,COG3523@2|Bacteria,1MV3D@1224|Proteobacteria,1RPQ2@1236|Gammaproteobacteria,1XSAX@135623|Vibrionales	135623|Vibrionales	S	protein conserved in bacteria	-	-	-	ko:K11891	ko02025,ko03070,map02025,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	IcmF-related,IcmF_C,ImcF-related_N
k141_992_3	55601.VANGNB10_cII0082	3.55e-157	461.0	COG3515@1|root,COG3515@2|Bacteria,1MWDQ@1224|Proteobacteria,1RQXI@1236|Gammaproteobacteria,1XW10@135623|Vibrionales	135623|Vibrionales	S	protein conserved in bacteria	-	-	-	ko:K11910	-	M00334	-	-	ko00000,ko00002,ko02044	3.A.23.1	-	-	ImpA_N,T6SS_VasJ
k141_992_4	1348635.BBJY01000001_gene2546	6.21e-46	158.0	2C9Y5@1|root,32RR9@2|Bacteria,1N3SX@1224|Proteobacteria,1SBDD@1236|Gammaproteobacteria,1XUFZ@135623|Vibrionales	135623|Vibrionales	S	Type VI secretion system VasI, EvfG, VC_A0118	-	-	-	ko:K11909	-	-	-	-	ko00000,ko02044	3.A.23.1	-	-	VasI
k141_993_1	1121396.KB893069_gene1376	5.95e-07	51.6	COG1338@1|root,COG1338@2|Bacteria,1MVBU@1224|Proteobacteria,42NDZ@68525|delta/epsilon subdivisions,2WKCN@28221|Deltaproteobacteria,2MHSW@213118|Desulfobacterales	28221|Deltaproteobacteria	N	Plays a role in the flagellum-specific transport system	fliP	-	-	ko:K02419	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	FliP
k141_993_2	1265505.ATUG01000001_gene3804	8.7e-07	52.4	COG3190@1|root,COG3190@2|Bacteria,1Q1ZT@1224|Proteobacteria,42VTD@68525|delta/epsilon subdivisions,2WRTA@28221|Deltaproteobacteria,2MM61@213118|Desulfobacterales	28221|Deltaproteobacteria	N	Flagellar biosynthesis protein, FliO	-	-	-	ko:K02418	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	FliO
k141_993_3	644282.Deba_2313	6.86e-07	48.1	COG1886@1|root,COG1886@2|Bacteria,1RGWT@1224|Proteobacteria,42TQB@68525|delta/epsilon subdivisions,2WQCQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	N	Flagellar motor switch protein FliN	fliN	-	-	ko:K02417	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	FliMN_C
k141_1674_2	243277.VC_0762	1.71e-161	465.0	COG1520@1|root,COG1520@2|Bacteria,1MXIJ@1224|Proteobacteria,1RN4V@1236|Gammaproteobacteria,1XSD2@135623|Vibrionales	135623|Vibrionales	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamB	GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0055114	-	ko:K17713	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	PQQ_2,PQQ_3
k141_1674_3	29495.EA26_03910	4.23e-76	234.0	COG2976@1|root,COG2976@2|Bacteria,1N117@1224|Proteobacteria,1S95P@1236|Gammaproteobacteria,1Y2NR@135623|Vibrionales	135623|Vibrionales	S	Tetratricopeptide repeat-like domain	-	-	-	-	-	-	-	-	-	-	-	-	TPR_21
k141_1674_6	29495.EA26_03895	2.84e-75	240.0	COG1426@1|root,COG1426@2|Bacteria,1N240@1224|Proteobacteria,1RQMV@1236|Gammaproteobacteria,1XSGH@135623|Vibrionales	135623|Vibrionales	S	protein conserved in bacteria	rodZ	-	-	ko:K15539	-	-	-	-	ko00000	-	-	-	DUF4115,HTH_25
k141_994_1	1304885.AUEY01000026_gene3564	9.1e-50	172.0	COG0595@1|root,COG0595@2|Bacteria,1MUGV@1224|Proteobacteria,42M65@68525|delta/epsilon subdivisions,2WIQ9@28221|Deltaproteobacteria,2MHNU@213118|Desulfobacterales	28221|Deltaproteobacteria	S	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay	rnj	-	-	ko:K12574	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	Lactamase_B,Lactamase_B_2,RMMBL
k141_3302_2	243277.VC_0389	8.38e-265	731.0	COG0025@1|root,COG0025@2|Bacteria,1MW5T@1224|Proteobacteria,1RPH6@1236|Gammaproteobacteria,1XTJG@135623|Vibrionales	135623|Vibrionales	P	COG0025 NhaP-type Na H and K H antiporters	-	-	-	ko:K03316	-	-	-	-	ko00000	2.A.36	-	-	Na_H_Exchanger
k141_3302_5	1348635.BBJY01000021_gene2874	7.52e-117	365.0	COG3307@1|root,COG3307@2|Bacteria,1N5VZ@1224|Proteobacteria,1RMC4@1236|Gammaproteobacteria,1XUTS@135623|Vibrionales	135623|Vibrionales	M	COG3307 Lipid A core - O-antigen ligase and related enzymes	-	-	-	ko:K13009	-	-	-	-	ko00000,ko01000,ko01005	-	-	-	PglL_A,Wzy_C,Wzy_C_2
k141_3302_7	243277.VC_0395	2.17e-188	525.0	COG1210@1|root,COG1210@2|Bacteria,1MV5F@1224|Proteobacteria,1RNDX@1236|Gammaproteobacteria,1XT3R@135623|Vibrionales	135623|Vibrionales	M	UTP--glucose-1-phosphate uridylyltransferase	galU	-	2.7.7.9	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	M00129,M00361,M00362,M00549	R00289	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
k141_3302_8	1219065.VPR01S_20_00880	9.3e-56	184.0	COG2197@1|root,COG2197@2|Bacteria,1R531@1224|Proteobacteria,1S18M@1236|Gammaproteobacteria,1XVDS@135623|Vibrionales	135623|Vibrionales	K	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	-	-	-	ko:K04333	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000	-	-	-	GerE
k141_3302_9	1051646.VITU9109_02692	1.28e-85	257.0	COG0629@1|root,COG0629@2|Bacteria,1RCWT@1224|Proteobacteria,1S3WP@1236|Gammaproteobacteria,1XSPW@135623|Vibrionales	135623|Vibrionales	L	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism	ssb	GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0006139,GO:0006259,GO:0006260,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
k141_3302_10	55601.VANGNB10_cI0276	1.95e-141	419.0	COG2199@1|root,COG2200@1|root,COG2199@2|Bacteria,COG2200@2|Bacteria,1MUQV@1224|Proteobacteria,1RN0Q@1236|Gammaproteobacteria,1XSFU@135623|Vibrionales	135623|Vibrionales	T	COG2199 FOG GGDEF domain	csrD	-	-	ko:K18765	-	-	-	-	ko00000,ko03019	-	-	-	EAL,GAPES4,GGDEF
k141_3303_1	1117318.PRUB_09374	3.16e-33	137.0	COG4251@1|root,COG4251@2|Bacteria,1NSQ1@1224|Proteobacteria,1T1YP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	4HB_MCP_1,CHASE3,GAF_2,HAMP,HATPase_c,HisKA,Hpt,PAS_3,PAS_4,PAS_9,Response_reg,SBP_bac_3
k141_995_1	1265505.ATUG01000001_gene3818	1.25e-167	492.0	COG1766@1|root,COG1766@2|Bacteria,1MUQR@1224|Proteobacteria,42N04@68525|delta/epsilon subdivisions,2WJS0@28221|Deltaproteobacteria,2MHWU@213118|Desulfobacterales	28221|Deltaproteobacteria	N	The M ring may be actively involved in energy transduction	fliF	-	-	ko:K02409	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	YscJ_FliF,YscJ_FliF_C
k141_995_2	1304885.AUEY01000003_gene525	3.03e-27	102.0	COG1677@1|root,COG1677@2|Bacteria,1NIFD@1224|Proteobacteria,42V59@68525|delta/epsilon subdivisions,2WSXK@28221|Deltaproteobacteria,2MKS3@213118|Desulfobacterales	28221|Deltaproteobacteria	NU	Flagellar hook-basal body complex protein FliE	fliE	-	-	ko:K02408	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliE
k141_995_3	1265505.ATUG01000001_gene3820	4.92e-62	196.0	COG1558@1|root,COG1558@2|Bacteria,1RHI3@1224|Proteobacteria,42TPI@68525|delta/epsilon subdivisions,2WP1C@28221|Deltaproteobacteria,2MJKP@213118|Desulfobacterales	28221|Deltaproteobacteria	N	Belongs to the flagella basal body rod proteins family	flgC	-	-	ko:K02388	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod,Flg_bbr_C
k141_995_4	1304885.AUEY01000003_gene523	1.11e-40	139.0	COG1815@1|root,COG1815@2|Bacteria,1PSBA@1224|Proteobacteria,42VSQ@68525|delta/epsilon subdivisions,2WPRI@28221|Deltaproteobacteria,2MK4Z@213118|Desulfobacterales	28221|Deltaproteobacteria	N	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body	-	-	-	ko:K02387	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod
k141_995_5	177437.HRM2_37330	3.25e-97	299.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WKG2@28221|Deltaproteobacteria,2MJ32@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Bacterial regulatory protein, Fis family	flbD	-	-	ko:K10943	ko02020,ko05111,map02020,map05111	M00515	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
k141_2683_2	1517681.HW45_14660	7.6e-68	212.0	COG0110@1|root,COG0110@2|Bacteria,1RA2T@1224|Proteobacteria,1S3ZZ@1236|Gammaproteobacteria,1XUHN@135623|Vibrionales	135623|Vibrionales	S	COG0110 Acetyltransferase (isoleucine patch superfamily)	-	-	2.3.1.79	ko:K00661	-	-	-	-	ko00000,ko01000	-	-	-	Hexapep,Hexapep_2,Mac
k141_2683_4	1283284.AZUK01000001_gene2458	4.49e-28	107.0	COG0561@1|root,COG0561@2|Bacteria,1Q5HK@1224|Proteobacteria,1RQ8H@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
k141_2683_5	1283284.AZUK01000001_gene2459	7.89e-153	432.0	COG1349@1|root,COG1349@2|Bacteria,1MXW2@1224|Proteobacteria,1RQDR@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	Transcriptional Regulator, DeoR family	-	-	-	-	-	-	-	-	-	-	-	-	DeoRC,HTH_DeoR
k141_2683_6	1123228.AUIH01000007_gene2492	8.68e-51	174.0	COG0679@1|root,COG0679@2|Bacteria,1RBBX@1224|Proteobacteria,1SZPB@1236|Gammaproteobacteria,1XJKG@135619|Oceanospirillales	135619|Oceanospirillales	S	Membrane transport protein	-	-	-	ko:K07088	-	-	-	-	ko00000	-	-	-	Mem_trans
k141_2683_7	931276.Cspa_c49720	8.78e-145	417.0	COG1477@1|root,COG1477@2|Bacteria,1TR9C@1239|Firmicutes,248KJ@186801|Clostridia,36DZZ@31979|Clostridiaceae	186801|Clostridia	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	-	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
k141_5346_57	1121289.JHVL01000003_gene2214	3.95e-71	215.0	COG2201@1|root,COG2201@2|Bacteria,1V3IU@1239|Firmicutes,24HJF@186801|Clostridia,36IRR@31979|Clostridiaceae	186801|Clostridia	NT	Chemotaxis protein cheY	cheY	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
k141_5346_58	1286171.EAL2_c13550	3.87e-137	404.0	COG1776@1|root,COG1886@1|root,COG1776@2|Bacteria,COG1886@2|Bacteria,1TPT8@1239|Firmicutes,24821@186801|Clostridia,25VY6@186806|Eubacteriaceae	186801|Clostridia	N	Type III flagellar switch regulator (C-ring) FliN C-term	fliN	-	-	ko:K02417	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	CheC,FliMN_C
k141_5346_59	1121324.CLIT_11c02010	1.65e-168	479.0	COG1868@1|root,COG1868@2|Bacteria,1TPTM@1239|Firmicutes,24AGV@186801|Clostridia	186801|Clostridia	N	flagellar motor switch protein FliM	fliM	-	-	ko:K02416	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliM,FliMN_C
k141_5346_60	1286171.EAL2_c13570	2.17e-34	123.0	COG1580@1|root,COG1580@2|Bacteria	2|Bacteria	N	Controls the rotational direction of flagella during chemotaxis	fliL	-	-	ko:K02415	-	-	-	-	ko00000,ko02035	-	-	-	FliL
k141_5346_61	999411.HMPREF1092_01494	4.38e-42	151.0	COG1360@1|root,COG1360@2|Bacteria,1V8KE@1239|Firmicutes,24GQQ@186801|Clostridia,36FHM@31979|Clostridiaceae	186801|Clostridia	N	PFAM OmpA MotB domain protein	motB	-	-	ko:K02557	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	MotB_plug,OmpA
k141_5346_62	1511.CLOST_1731	2.71e-118	345.0	COG1291@1|root,COG1291@2|Bacteria,1TRH1@1239|Firmicutes,24AEJ@186801|Clostridia,25S1P@186804|Peptostreptococcaceae	186801|Clostridia	N	MotA/TolQ/ExbB proton channel family	motA	-	-	ko:K02556	ko02020,ko02030,ko02040,map02020,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	MotA_ExbB
k141_5346_63	1121324.CLIT_11c01970	1.22e-15	70.9	COG1582@1|root,COG1582@2|Bacteria,1VKHB@1239|Firmicutes,24RWI@186801|Clostridia	186801|Clostridia	N	PFAM flagellar FlbD family protein	flbD	-	-	ko:K02385	-	-	-	-	ko00000,ko02035	-	-	-	FlbD
k141_5346_64	1410625.JHWK01000003_gene1824	3.34e-62	218.0	COG1749@1|root,COG1749@2|Bacteria,1UHS7@1239|Firmicutes,247ZT@186801|Clostridia,27I5I@186928|unclassified Lachnospiraceae	186801|Clostridia	N	Flagellar basal body rod FlgEFG protein C-terminal	flgE	-	-	ko:K02390	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FlaE,Flg_bb_rod,Flg_bbr_C
k141_5346_65	608506.COB47_1947	2.23e-17	82.0	COG1843@1|root,COG1843@2|Bacteria,1VF85@1239|Firmicutes,24QKD@186801|Clostridia,42HFM@68295|Thermoanaerobacterales	186801|Clostridia	N	PFAM flagellar hook capping protein	flgD	-	-	ko:K02389	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FLgD_tudor,FlgD
k141_5346_66	864565.HMPREF0379_0460	1.28e-09	68.9	COG3144@1|root,COG3144@2|Bacteria,1VAP1@1239|Firmicutes,24UIZ@186801|Clostridia	186801|Clostridia	N	PFAM flagellar hook-length control	-	-	-	ko:K02414	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_hook
k141_5346_68	1408321.JNJD01000006_gene897	3.73e-06	51.6	COG2882@1|root,COG2882@2|Bacteria,1VK96@1239|Firmicutes,24RWK@186801|Clostridia,27NTH@186928|unclassified Lachnospiraceae	186801|Clostridia	NOU	Flagellar FliJ protein	fliJ	-	-	ko:K02413	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliJ
k141_5346_69	1511.CLOST_1738	3.7e-242	674.0	COG1157@1|root,COG1157@2|Bacteria,1TP0R@1239|Firmicutes,25E6B@186801|Clostridia,25S4K@186804|Peptostreptococcaceae	186801|Clostridia	NU	ATP synthase alpha/beta family, beta-barrel domain	fliI	-	3.6.3.14	ko:K02412,ko:K03224	ko02040,ko03070,map02040,map03070	M00332,M00542,M00660	-	-	ko00000,ko00001,ko00002,ko01000,ko02035,ko02044	3.A.6.1,3.A.6.2,3.A.6.3	-	-	ATP-synt_ab,ATP-synt_ab_N
k141_5346_70	1121324.CLIT_11c01900	8.07e-33	129.0	COG1317@1|root,COG1317@2|Bacteria	2|Bacteria	N	bacterial-type flagellum organization	fliH	-	-	ko:K02411,ko:K03223	ko02040,ko03070,map02040,map03070	M00332,M00660	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.6.1,3.A.6.2,3.A.6.3	-	-	FliH
k141_5346_71	1121324.CLIT_11c01890	5.52e-180	508.0	COG1536@1|root,COG1536@2|Bacteria,1TP01@1239|Firmicutes,2480B@186801|Clostridia	186801|Clostridia	N	Flagellar motor switch protein flig	fliG	-	-	ko:K02410	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliG_C,FliG_M,FliG_N
k141_5346_72	1286171.EAL2_c13690	1.64e-131	399.0	COG1766@1|root,COG1766@2|Bacteria,1TRK0@1239|Firmicutes,2498Q@186801|Clostridia,25WPD@186806|Eubacteriaceae	186801|Clostridia	N	Flagellar M-ring protein	fliF	-	-	ko:K02409	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	YscJ_FliF,YscJ_FliF_C
k141_5346_73	1286171.EAL2_c13700	2.92e-20	85.1	COG1677@1|root,COG1677@2|Bacteria,1UG7J@1239|Firmicutes,25NGB@186801|Clostridia,25XGJ@186806|Eubacteriaceae	186801|Clostridia	N	Flagellar hook-basal body complex protein FliE	fliE	-	-	ko:K02408	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliE
k141_5346_74	1511.CLOST_1743	1.22e-54	175.0	COG1558@1|root,COG1558@2|Bacteria,1V6NB@1239|Firmicutes,24JJW@186801|Clostridia,25TJT@186804|Peptostreptococcaceae	186801|Clostridia	N	Belongs to the flagella basal body rod proteins family	flgC	-	-	ko:K02388	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod,Flg_bbr_C
k141_5346_75	999423.HMPREF9161_01744	2.49e-10	62.0	COG1815@1|root,COG1815@2|Bacteria,1VEUZ@1239|Firmicutes	1239|Firmicutes	N	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body	flgB	-	-	ko:K02387	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod
k141_5346_76	1511.CLOST_1745	9.99e-165	470.0	COG0687@1|root,COG0687@2|Bacteria,1TPY1@1239|Firmicutes,2483K@186801|Clostridia,25R00@186804|Peptostreptococcaceae	186801|Clostridia	P	Bacterial extracellular solute-binding protein	potD	-	-	ko:K11069	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	BPD_transp_1,SBP_bac_6,SBP_bac_8
k141_5346_77	546269.HMPREF0389_00718	3.27e-106	315.0	COG1177@1|root,COG1177@2|Bacteria,1V0VD@1239|Firmicutes,25E3C@186801|Clostridia,25QHZ@186804|Peptostreptococcaceae	186801|Clostridia	P	ABC transporter permease	-	-	-	ko:K11070	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	BPD_transp_1
k141_5346_78	1511.CLOST_1747	4.38e-127	369.0	COG1176@1|root,COG1176@2|Bacteria,1TQ7Z@1239|Firmicutes,247Y8@186801|Clostridia,25QQU@186804|Peptostreptococcaceae	186801|Clostridia	P	ABC transporter permease	potB	-	-	ko:K11071	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	BPD_transp_1
k141_5346_79	445973.CLOBAR_01040	1.99e-155	447.0	COG3842@1|root,COG3842@2|Bacteria,1TP2M@1239|Firmicutes,247JR@186801|Clostridia,25QEJ@186804|Peptostreptococcaceae	186801|Clostridia	P	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system	potA	-	3.6.3.31	ko:K11072	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.11.1	-	-	ABC_tran,TOBE_2
k141_5346_80	469618.FVAG_00474	2.82e-159	471.0	COG1306@1|root,COG1306@2|Bacteria,379EF@32066|Fusobacteria	32066|Fusobacteria	S	Putative glycosyl hydrolase domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4015
k141_5346_81	1121324.CLIT_23c04660	6.18e-159	451.0	COG1737@1|root,COG1737@2|Bacteria,1TP7H@1239|Firmicutes,248ZD@186801|Clostridia,25QFH@186804|Peptostreptococcaceae	186801|Clostridia	K	Helix-turn-helix domain, rpiR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_6,SIS
k141_5346_82	1408422.JHYF01000016_gene126	3.02e-65	204.0	COG1014@1|root,COG1014@2|Bacteria,1V3RG@1239|Firmicutes,24I3Y@186801|Clostridia,36IU6@31979|Clostridiaceae	186801|Clostridia	C	Pyruvate ferredoxin/flavodoxin oxidoreductase	korC	-	1.2.7.3	ko:K00177	ko00020,ko00720,ko01100,ko01120,ko01200,map00020,map00720,map01100,map01120,map01200	M00009,M00011,M00173,M00620	R01197	RC00004,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	POR
k141_5346_83	1123009.AUID01000036_gene1241	2.05e-167	471.0	COG1013@1|root,COG1013@2|Bacteria,1TQJ2@1239|Firmicutes,25CAJ@186801|Clostridia,26A2N@186813|unclassified Clostridiales	186801|Clostridia	C	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain	korB	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
k141_5346_84	1123009.AUID01000036_gene1242	3.99e-203	570.0	COG0674@1|root,COG0674@2|Bacteria,1TSSC@1239|Firmicutes,248I6@186801|Clostridia,26ANE@186813|unclassified Clostridiales	186801|Clostridia	C	Pyruvate:ferredoxin oxidoreductase core domain II	korA	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR_N
k141_5346_85	1123009.AUID01000036_gene1243	7.53e-29	104.0	COG1146@1|root,COG1146@2|Bacteria,1VFGN@1239|Firmicutes,25FSQ@186801|Clostridia	186801|Clostridia	C	PFAM 4Fe-4S	-	-	1.2.7.3	ko:K00176	ko00020,ko00720,ko01100,ko01120,ko01200,map00020,map00720,map01100,map01120,map01200	M00009,M00011,M00173,M00620	R01197	RC00004,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_4,Fer4_7,Fer4_9
k141_5346_86	688269.Theth_1049	6.86e-61	199.0	COG0496@1|root,COG0496@2|Bacteria,2GC9F@200918|Thermotogae	200918|Thermotogae	F	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates	surE	-	3.1.3.5	ko:K03787	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	SurE
k141_5346_87	1111732.AZOD01000012_gene1305	2.46e-33	125.0	COG2519@1|root,COG2519@2|Bacteria,1QX2B@1224|Proteobacteria,1T5KY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	J	Putative rRNA methylase	-	-	-	-	-	-	-	-	-	-	-	-	rRNA_methylase
k141_5346_89	1230342.CTM_07461	4.98e-95	285.0	COG1187@1|root,COG1187@2|Bacteria,1TP68@1239|Firmicutes,248UG@186801|Clostridia,36EH3@31979|Clostridiaceae	186801|Clostridia	J	Belongs to the pseudouridine synthase RsuA family	rluB	-	5.4.99.19,5.4.99.22	ko:K06178,ko:K06183	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
k141_1464_17	511062.GU3_07150	2.5e-61	192.0	COG2259@1|root,COG2259@2|Bacteria,1RDYW@1224|Proteobacteria,1S3RT@1236|Gammaproteobacteria,1Y6CS@135624|Aeromonadales	135624|Aeromonadales	S	DoxX	-	-	-	ko:K15977	-	-	-	-	ko00000	-	-	-	DoxX
k141_1464_18	722419.PH505_al00870	6.17e-125	366.0	COG0583@1|root,COG0583@2|Bacteria,1MW16@1224|Proteobacteria,1RPNX@1236|Gammaproteobacteria,2Q0JN@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
k141_1464_21	386415.NT01CX_0237	2.42e-30	135.0	COG2199@1|root,COG2203@1|root,COG3899@1|root,COG2203@2|Bacteria,COG3706@2|Bacteria,COG3899@2|Bacteria,1V9Y7@1239|Firmicutes,24A8B@186801|Clostridia,36E8P@31979|Clostridiaceae	186801|Clostridia	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GGDEF,Pkinase,TPR_12,TPR_8
k141_1464_22	572480.Arnit_0816	9.39e-54	181.0	2AFRW@1|root,315TV@2|Bacteria,1PW73@1224|Proteobacteria,42ZYA@68525|delta/epsilon subdivisions,2YRUR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_1464_23	675814.VIC_003475	6.48e-127	372.0	COG1234@1|root,COG1234@2|Bacteria,1Q4PW@1224|Proteobacteria,1RR5K@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA	rnz	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004527,GO:0004532,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016796,GO:0016891,GO:0016893,GO:0016896,GO:0031123,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0042779,GO:0042780,GO:0042781,GO:0043167,GO:0043169,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0046483,GO:0046872,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0090503,GO:0140098,GO:1901360,GO:1905267	3.1.26.11	ko:K00784	ko03013,map03013	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	Lactamase_B_2
k141_1464_24	1121939.L861_17480	1.64e-75	229.0	COG1432@1|root,COG1432@2|Bacteria,1MUAE@1224|Proteobacteria,1S47Z@1236|Gammaproteobacteria,1XJQI@135619|Oceanospirillales	135619|Oceanospirillales	S	nuclease	-	-	-	-	-	-	-	-	-	-	-	-	NYN
k141_1464_26	1353529.M899_3007	5.27e-36	126.0	COG1832@1|root,COG1832@2|Bacteria,1PUW7@1224|Proteobacteria,42T5D@68525|delta/epsilon subdivisions,2WPHZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	CoA binding domain	-	-	-	ko:K06929	-	-	-	-	ko00000	-	-	-	CoA_binding_2
k141_1464_27	1515746.HR45_05680	4.79e-194	553.0	COG0477@1|root,COG2814@2|Bacteria,1MW19@1224|Proteobacteria,1RMSZ@1236|Gammaproteobacteria,2QDR4@267890|Shewanellaceae	1236|Gammaproteobacteria	EGP	Major Facilitator Superfamily	-	-	-	ko:K07552	-	-	-	-	ko00000,ko02000	2.A.1.2	-	-	MFS_1
k141_1464_28	1344012.ATMI01000054_gene1718	8.39e-144	415.0	COG0667@1|root,COG0667@2|Bacteria,1MV2Y@1224|Proteobacteria,1RQ1X@1236|Gammaproteobacteria,4BVPM@82986|Tatumella	1236|Gammaproteobacteria	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
k141_1464_29	1348635.BBJY01000005_gene3165	6.36e-69	212.0	COG2731@1|root,COG2731@2|Bacteria,1RA6C@1224|Proteobacteria,1S281@1236|Gammaproteobacteria,1XW6G@135623|Vibrionales	135623|Vibrionales	G	COG2731 Beta-galactosidase, beta subunit	-	-	-	ko:K19334	-	-	-	-	ko00000,ko02048	-	-	-	DUF386
k141_1464_30	575788.VS_II0070	3.69e-80	244.0	COG1011@1|root,COG1011@2|Bacteria,1PGNF@1224|Proteobacteria,1RRDC@1236|Gammaproteobacteria,1XVRH@135623|Vibrionales	135623|Vibrionales	S	hydrolase (HAD superfamily)	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2
k141_1464_31	1208321.D104_11675	1.89e-140	405.0	COG0697@1|root,COG0697@2|Bacteria,1RDQ0@1224|Proteobacteria,1SNBH@1236|Gammaproteobacteria	1236|Gammaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
k141_1464_33	1051646.VITU9109_14943	2.15e-205	596.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,1XTQG@135623|Vibrionales	135623|Vibrionales	NT	methyl-accepting chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal,dCache_1
k141_1464_34	1348635.BBJY01000001_gene2364	1.85e-178	509.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,1RPN9@1236|Gammaproteobacteria,1XSW1@135623|Vibrionales	135623|Vibrionales	S	COG0488 ATPase components of ABC transporters with duplicated ATPase domains	ybiT	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,ABC_tran_Xtn
k141_528_2	745014.OMB55_00016730	2.84e-07	58.2	COG1639@1|root,COG1639@2|Bacteria,1N7EN@1224|Proteobacteria,1RT8G@1236|Gammaproteobacteria,1J4P0@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	T	Signal transduction protein	-	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	HDOD
k141_3169_1	1415778.JQMM01000001_gene948	3.09e-14	80.1	COG1629@1|root,COG4771@2|Bacteria,1MX42@1224|Proteobacteria,1RQ2K@1236|Gammaproteobacteria,1J5EX@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	P	COG1629 Outer membrane receptor proteins, mostly Fe transport	hmuR	GO:0005575,GO:0005623,GO:0008150,GO:0009279,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0042221,GO:0044462,GO:0044464,GO:0050896,GO:0051716,GO:0070887,GO:0071241,GO:0071248,GO:0071281,GO:0071944	-	ko:K16087	-	-	-	-	ko00000,ko02000	1.B.14.2	-	-	Plug,TonB_dep_Rec
k141_4171_2	1515746.HR45_07760	2.69e-190	538.0	COG0620@1|root,COG0620@2|Bacteria,1MV2Z@1224|Proteobacteria,1RPTM@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	methionine synthase	-	-	-	-	-	-	-	-	-	-	-	-	Meth_synt_2
k141_4171_3	1280001.BAOA01000100_gene4462	2.35e-144	418.0	COG1262@1|root,COG1262@2|Bacteria,1PDSD@1224|Proteobacteria,1S4ZV@1236|Gammaproteobacteria,1XVWH@135623|Vibrionales	135623|Vibrionales	S	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
k141_3527_43	1219065.VPR01S_11_01560	1.23e-56	185.0	2CJ6B@1|root,32S9B@2|Bacteria,1N2I4@1224|Proteobacteria,1S8Z8@1236|Gammaproteobacteria,1XWS0@135623|Vibrionales	135623|Vibrionales	S	Thermostable hemolysin	-	-	-	-	-	-	-	-	-	-	-	-	T_hemolysin
k141_3527_44	55601.VANGNB10_cII0200	5.77e-68	213.0	COG4976@1|root,COG4976@2|Bacteria,1QV99@1224|Proteobacteria,1T2AQ@1236|Gammaproteobacteria,1Y346@135623|Vibrionales	135623|Vibrionales	S	DREV methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
k141_3527_45	675816.VIA_000834	1.37e-29	107.0	2AWFJ@1|root,31NBT@2|Bacteria,1QK2U@1224|Proteobacteria,1TI5K@1236|Gammaproteobacteria,1XYFB@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_3527_46	675813.VIB_002433	2.78e-102	298.0	COG1670@1|root,COG1670@2|Bacteria,1PDMH@1224|Proteobacteria,1RPZ4@1236|Gammaproteobacteria,1XVMW@135623|Vibrionales	135623|Vibrionales	J	COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins	speG	GO:0000287,GO:0003674,GO:0003824,GO:0004145,GO:0005488,GO:0006576,GO:0006595,GO:0006598,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0009056,GO:0009308,GO:0009310,GO:0009987,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0034641,GO:0042402,GO:0043167,GO:0043169,GO:0044106,GO:0044237,GO:0046872,GO:0071704,GO:1901564,GO:1901565,GO:1901575	2.3.1.57	ko:K00657	ko00330,ko01100,ko04216,map00330,map01100,map04216	M00135	R01154	RC00004,RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetyltransf_3
k141_3527_47	55601.VANGNB10_cII0870c	2.86e-51	162.0	COG0760@1|root,COG0760@2|Bacteria,1MZDK@1224|Proteobacteria,1S9DN@1236|Gammaproteobacteria,1XXXZ@135623|Vibrionales	135623|Vibrionales	G	COG0760 Parvulin-like peptidyl-prolyl isomerase	ppiC	-	5.2.1.8	ko:K03769	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase_3
k141_3527_48	243277.VC_A0954	8.72e-168	474.0	COG0784@1|root,COG0835@1|root,COG0784@2|Bacteria,COG0835@2|Bacteria,1PQPU@1224|Proteobacteria,1RYEZ@1236|Gammaproteobacteria,1XTKV@135623|Vibrionales	135623|Vibrionales	T	COG0835 Chemotaxis signal transduction protein	-	-	-	ko:K03415	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	CheW,Response_reg
k141_3527_49	675815.VOA_001022	2.46e-116	355.0	COG2199@1|root,COG3452@1|root,COG2199@2|Bacteria,COG3452@2|Bacteria,1R4NG@1224|Proteobacteria,1S0XZ@1236|Gammaproteobacteria,1XU79@135623|Vibrionales	135623|Vibrionales	T	periplasmic ligand-binding sensor domain	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,GGDEF
k141_3527_50	223926.28808334	2.73e-140	410.0	29HQP@1|root,304MY@2|Bacteria,1RFYR@1224|Proteobacteria,1S5CC@1236|Gammaproteobacteria,1Y2A9@135623|Vibrionales	135623|Vibrionales	S	Domain of unknown function (DUF3541)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3541
k141_3527_52	675814.VIC_002462	4.52e-133	385.0	COG1741@1|root,COG1741@2|Bacteria,1MWIP@1224|Proteobacteria,1RNVM@1236|Gammaproteobacteria,1XU4P@135623|Vibrionales	135623|Vibrionales	S	Belongs to the pirin family	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin,Pirin_C
k141_3527_55	617140.AJZE01000093_gene2493	2.69e-168	481.0	COG0668@1|root,COG0668@2|Bacteria,1MXD2@1224|Proteobacteria,1RNUB@1236|Gammaproteobacteria,1XUER@135623|Vibrionales	135623|Vibrionales	M	COG0668 Small-conductance mechanosensitive channel	ynaI	-	-	ko:K16052	-	-	-	-	ko00000,ko02000	1.A.23.4	-	-	MS_channel
k141_3527_56	675815.VOA_001034	0.0	1266.0	COG1067@1|root,COG1067@2|Bacteria,1MWGB@1224|Proteobacteria,1RMPC@1236|Gammaproteobacteria,1XSB9@135623|Vibrionales	135623|Vibrionales	O	Belongs to the peptidase S16 family	-	-	-	-	-	-	-	-	-	-	-	-	AAA_32,Lon_C
k141_3527_57	345073.VC395_A1059	3.24e-216	602.0	COG0722@1|root,COG0722@2|Bacteria,1MU5Q@1224|Proteobacteria,1RMAA@1236|Gammaproteobacteria,1XSHG@135623|Vibrionales	135623|Vibrionales	E	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)	aroG	-	2.5.1.54	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_1
k141_3527_58	675813.VIB_002705	2.49e-248	700.0	COG1109@1|root,COG1109@2|Bacteria,1QUGD@1224|Proteobacteria,1RQME@1236|Gammaproteobacteria,1XVES@135623|Vibrionales	135623|Vibrionales	G	Phosphoglucomutase phosphomannomutase alpha beta subunit	-	-	5.4.2.8	ko:K01840	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01818	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
k141_3527_59	316275.VSAL_I1190	2.19e-69	217.0	COG0179@1|root,COG0179@2|Bacteria,1MVFA@1224|Proteobacteria,1S8KH@1236|Gammaproteobacteria,1XTE3@135623|Vibrionales	135623|Vibrionales	Q	COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)	-	-	-	-	-	-	-	-	-	-	-	-	FAA_hydrolase
k141_3527_60	1219076.N646_4642	1.98e-36	127.0	2AW94@1|root,31N4F@2|Bacteria,1QJVW@1224|Proteobacteria,1THXH@1236|Gammaproteobacteria,1XXTY@135623|Vibrionales	135623|Vibrionales	-	-	VPA0521	-	-	-	-	-	-	-	-	-	-	-	-
k141_3527_61	1348635.BBJY01000010_gene1272	1.38e-175	505.0	COG0739@1|root,COG1388@1|root,COG0739@2|Bacteria,COG1388@2|Bacteria,1MVTF@1224|Proteobacteria,1RM7S@1236|Gammaproteobacteria,1XSZJ@135623|Vibrionales	135623|Vibrionales	M	COG0739 Membrane proteins related to metalloendopeptidases	-	-	-	-	-	-	-	-	-	-	-	-	OapA,Peptidase_M23
k141_3527_62	55601.VANGNB10_cII0905c	2.34e-51	163.0	COG0296@1|root,COG0296@2|Bacteria,1N8WX@1224|Proteobacteria,1SG9V@1236|Gammaproteobacteria,1XY0F@135623|Vibrionales	135623|Vibrionales	G	PFAM glycoside hydrolase, family 13	-	-	-	-	-	-	-	-	-	-	-	-	AMPK1_CBM
k141_3527_63	1219065.VPR01S_12_00580	4.51e-218	615.0	COG3314@1|root,COG3314@2|Bacteria,1NEAN@1224|Proteobacteria,1RPX6@1236|Gammaproteobacteria,1XTQR@135623|Vibrionales	135623|Vibrionales	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	Gate
k141_3527_64	945543.VIBR0546_07142	1.54e-165	464.0	COG1117@1|root,COG1117@2|Bacteria,1MU16@1224|Proteobacteria,1RNUF@1236|Gammaproteobacteria,1XT9N@135623|Vibrionales	135623|Vibrionales	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB2	GO:0003674,GO:0003824,GO:0005215,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015114,GO:0015318,GO:0015399,GO:0015405,GO:0015415,GO:0015698,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0034220,GO:0035435,GO:0042623,GO:0042626,GO:0043225,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0098656,GO:0098660,GO:0098661,GO:0099133	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
k141_3527_65	55601.VANGNB10_cII0911c	1.93e-171	482.0	COG0581@1|root,COG0581@2|Bacteria,1MUWB@1224|Proteobacteria,1S1FS@1236|Gammaproteobacteria,1XT07@135623|Vibrionales	135623|Vibrionales	P	Phosphate transport system permease	-	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
k141_3527_66	1219065.VPR01S_12_00650	5.13e-174	491.0	COG0573@1|root,COG0573@2|Bacteria,1MVKP@1224|Proteobacteria,1RQXJ@1236|Gammaproteobacteria,1XSNI@135623|Vibrionales	135623|Vibrionales	P	probably responsible for the translocation of the substrate across the membrane	pstC	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
k141_3527_67	29495.EA26_13090	1.19e-158	449.0	COG0226@1|root,COG0226@2|Bacteria,1RD2K@1224|Proteobacteria,1T0KP@1236|Gammaproteobacteria,1XUIY@135623|Vibrionales	135623|Vibrionales	P	ABC-type phosphate transport system, periplasmic component	pstS	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
k141_3527_68	675814.VIC_002386	6.23e-250	694.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,1RMWA@1236|Gammaproteobacteria,1XUCT@135623|Vibrionales	135623|Vibrionales	L	Belongs to the DEAD box helicase family	-	-	-	-	-	-	-	-	-	-	-	-	DEAD,Helicase_C
k141_3527_69	1051646.VITU9109_07498	3.88e-15	70.9	COG4238@1|root,COG4238@2|Bacteria,1MZCW@1224|Proteobacteria,1S8YB@1236|Gammaproteobacteria,1XYBW@135623|Vibrionales	135623|Vibrionales	M	Outer membrane lipoprotein	lpp	-	-	ko:K06078	-	-	-	-	ko00000,ko01011	-	-	-	LPP
k141_3527_70	1219065.VPR01S_12_00690	2.44e-155	443.0	COG1376@1|root,COG1376@2|Bacteria,1MVYT@1224|Proteobacteria,1RMNC@1236|Gammaproteobacteria,1XT0M@135623|Vibrionales	135623|Vibrionales	M	protein conserved in bacteria	-	-	-	ko:K16291,ko:K19236	ko01503,map01503	-	-	-	ko00000,ko00001,ko01002,ko01011	-	-	-	LysM,YkuD
k141_3527_71	55601.VANGNB10_cII0148	1.93e-204	581.0	COG0415@1|root,COG0415@2|Bacteria,1MV9Y@1224|Proteobacteria,1RNGJ@1236|Gammaproteobacteria,1XUEN@135623|Vibrionales	135623|Vibrionales	H	Belongs to the DNA photolyase family	phrB	GO:0003674,GO:0003824,GO:0003904,GO:0003913,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016830,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360	4.1.99.3	ko:K01669	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_photolyase,FAD_binding_7
k141_3527_72	55601.VANGNB10_cII0143c	1.07e-193	555.0	COG0457@1|root,COG0457@2|Bacteria,1NFT4@1224|Proteobacteria,1SPMW@1236|Gammaproteobacteria,1XSHX@135623|Vibrionales	135623|Vibrionales	S	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_3527_73	945550.VISI1226_13101	3.24e-212	605.0	COG0457@1|root,COG2199@1|root,COG0457@2|Bacteria,COG3706@2|Bacteria,1NC00@1224|Proteobacteria,1SNFZ@1236|Gammaproteobacteria,1XSA5@135623|Vibrionales	135623|Vibrionales	T	COG2199 FOG GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
k141_3527_74	1219065.VPR01S_12_00870	6.46e-148	424.0	COG2035@1|root,COG2035@2|Bacteria,1MXVI@1224|Proteobacteria,1RN4B@1236|Gammaproteobacteria,1XSHN@135623|Vibrionales	135623|Vibrionales	S	Domain of unknown function (DUF368)	-	-	-	ko:K08974	-	-	-	-	ko00000	-	-	-	DUF368
k141_3527_75	1348635.BBJY01000001_gene2354	3.14e-201	567.0	COG3633@1|root,COG3633@2|Bacteria,1MXE1@1224|Proteobacteria,1RP9B@1236|Gammaproteobacteria,1XSMF@135623|Vibrionales	135623|Vibrionales	E	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)	sstT	GO:0003674,GO:0005215,GO:0005310,GO:0005342,GO:0005343,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0006820,GO:0006835,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015077,GO:0015081,GO:0015291,GO:0015293,GO:0015294,GO:0015318,GO:0015370,GO:0015672,GO:0015711,GO:0015849,GO:0017153,GO:0022804,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0035725,GO:0046873,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0098655,GO:0098656,GO:0098660,GO:0098662,GO:1903825,GO:1905039	-	ko:K07862	-	-	-	-	ko00000,ko02000	2.A.23.4	-	-	SDF
k141_3527_76	55601.VANGNB10_cII0130	5.76e-124	369.0	COG0790@1|root,COG0790@2|Bacteria,1N6ZB@1224|Proteobacteria,1SYIP@1236|Gammaproteobacteria,1XU4U@135623|Vibrionales	135623|Vibrionales	S	COG0790 FOG TPR repeat, SEL1 subfamily	-	-	-	-	-	-	-	-	-	-	-	-	Sel1
k141_3527_77	1348635.BBJY01000001_gene2449	0.0	993.0	COG1523@1|root,COG1523@2|Bacteria,1MU19@1224|Proteobacteria,1RP6F@1236|Gammaproteobacteria,1XTF4@135623|Vibrionales	135623|Vibrionales	G	Belongs to the glycosyl hydrolase 13 family	glgX	-	3.2.1.68	ko:K01214	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R09995,R11261	-	ko00000,ko00001,ko00002,ko01000	-	CBM48,GH13	-	Alpha-amylase,CBM_48
k141_3527_78	55601.VANGNB10_cII0111c	0.0	884.0	COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,1RMUR@1236|Gammaproteobacteria,1XSH6@135623|Vibrionales	135623|Vibrionales	V	COG1132 ABC-type multidrug transport system, ATPase and permease components	vcaM	-	-	ko:K18893	ko02010,map02010	-	-	-	ko00000,ko00001,ko02000	3.A.1	-	-	ABC_membrane,ABC_tran
k141_3527_79	55601.VANGNB10_cII0110c	1.81e-82	253.0	COG2733@1|root,COG2733@2|Bacteria,1R4JT@1224|Proteobacteria,1RRVB@1236|Gammaproteobacteria,1XU14@135623|Vibrionales	135623|Vibrionales	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF445
k141_3527_81	1348635.BBJY01000001_gene2460	8.16e-131	376.0	COG1414@1|root,COG1414@2|Bacteria,1R57R@1224|Proteobacteria,1S4GT@1236|Gammaproteobacteria,1XSUP@135623|Vibrionales	135623|Vibrionales	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_11,HTH_20,HTH_IclR,IclR
k141_3527_82	55601.VANGNB10_cII0103	2.43e-221	636.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,1XVCZ@135623|Vibrionales	135623|Vibrionales	NT	methyl-accepting chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal,dCache_1
k141_3527_83	55601.VANGNB10_cII0097	2.78e-249	694.0	COG0471@1|root,COG0471@2|Bacteria,1MUSA@1224|Proteobacteria,1RPU5@1236|Gammaproteobacteria,1XVCC@135623|Vibrionales	135623|Vibrionales	P	COG0471 Di- and tricarboxylate transporters	-	-	-	ko:K14445	-	-	-	-	ko00000,ko02000	2.A.47.1	-	-	Na_sulph_symp
k141_3527_84	243277.VC_1091	8.8e-295	816.0	COG4166@1|root,COG4166@2|Bacteria,1P91R@1224|Proteobacteria,1RN57@1236|Gammaproteobacteria,1XTB9@135623|Vibrionales	135623|Vibrionales	E	COG4166 ABC-type oligopeptide transport system, periplasmic component	oppA	-	-	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	SBP_bac_5
k141_3527_85	345073.VC395_1107	1.32e-183	514.0	COG0601@1|root,COG0601@2|Bacteria,1MU8Z@1224|Proteobacteria,1RNJ1@1236|Gammaproteobacteria,1XUSF@135623|Vibrionales	135623|Vibrionales	P	COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components	oppB	-	-	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1
k141_3527_86	1280001.BAOA01000020_gene381	1.06e-175	494.0	COG1173@1|root,COG1173@2|Bacteria,1MU26@1224|Proteobacteria,1RND6@1236|Gammaproteobacteria,1XT8X@135623|Vibrionales	135623|Vibrionales	P	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components	oppC	-	-	ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1,OppC_N
k141_3527_87	674977.VMC_28100	8.99e-209	580.0	COG0444@1|root,COG0444@2|Bacteria,1R4KB@1224|Proteobacteria,1SMBI@1236|Gammaproteobacteria,1XSWQ@135623|Vibrionales	135623|Vibrionales	P	Belongs to the ABC transporter superfamily	oppD	-	-	ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
k141_3527_88	55601.VANGNB10_cI1743c	9.83e-202	562.0	COG4608@1|root,COG4608@2|Bacteria,1NU4K@1224|Proteobacteria,1SKPD@1236|Gammaproteobacteria,1XUJP@135623|Vibrionales	135623|Vibrionales	P	Belongs to the ABC transporter superfamily	oppF	-	-	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
k141_3527_89	1348635.BBJY01000034_gene2217	4.69e-45	156.0	COG3381@1|root,COG3381@2|Bacteria,1RF2Y@1224|Proteobacteria,1S3Q9@1236|Gammaproteobacteria,1XY9W@135623|Vibrionales	135623|Vibrionales	S	Nitrate reductase delta subunit	-	-	-	-	-	-	-	-	-	-	-	-	Nitrate_red_del
k141_3527_91	1116375.VEJY3_22346	1.29e-76	241.0	COG1266@1|root,COG1266@2|Bacteria,1P0IE@1224|Proteobacteria,1RS9M@1236|Gammaproteobacteria,1XV8N@135623|Vibrionales	135623|Vibrionales	S	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
k141_3527_92	1515746.HR45_17945	1.16e-236	662.0	COG0477@1|root,COG2814@2|Bacteria,1MVKJ@1224|Proteobacteria,1T1VM@1236|Gammaproteobacteria	1236|Gammaproteobacteria	EGP	Major Facilitator	ygcS	-	-	ko:K08176,ko:K08368	-	-	-	-	ko00000,ko02000	2.A.1,2.A.1.9	-	-	Sugar_tr
k141_3527_93	223926.28806477	1.07e-77	265.0	COG0840@1|root,COG0840@2|Bacteria,1RCN5@1224|Proteobacteria,1S2HR@1236|Gammaproteobacteria,1XSW3@135623|Vibrionales	135623|Vibrionales	NT	methyl-accepting chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal
k141_3527_94	458817.Shal_4016	1.71e-90	300.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,2Q98T@267890|Shewanellaceae	1236|Gammaproteobacteria	NT	PFAM histidine kinase, HAMP region domain protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal,dCache_1,sCache_2
k141_3527_95	1348635.BBJY01000013_gene1067	5.23e-219	613.0	COG1301@1|root,COG1301@2|Bacteria,1MU0Q@1224|Proteobacteria,1RMEN@1236|Gammaproteobacteria,1XU7P@135623|Vibrionales	135623|Vibrionales	U	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family	-	-	-	-	-	-	-	-	-	-	-	-	SDF
k141_3527_96	1205908.AKXW01000005_gene3299	6.87e-219	610.0	COG1929@1|root,COG1929@2|Bacteria,1MVG9@1224|Proteobacteria,1RMC6@1236|Gammaproteobacteria,1XSHV@135623|Vibrionales	135623|Vibrionales	G	Belongs to the glycerate kinase type-1 family	glxK	-	2.7.1.165	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	-	R08572	RC00002,RC00428	ko00000,ko00001,ko01000	-	-	-	Gly_kinase
k141_3527_97	672.VV93_v1c24640	4.25e-233	649.0	COG2610@1|root,COG2610@2|Bacteria,1MXVK@1224|Proteobacteria,1RM8R@1236|Gammaproteobacteria,1XVKM@135623|Vibrionales	135623|Vibrionales	EG	COG2610 H gluconate symporter and related permeases	-	-	-	ko:K03299	-	-	-	-	ko00000,ko02000	2.A.8	-	-	GntP_permease
k141_3527_98	672.VV93_v1c24630	4.48e-167	481.0	COG3835@1|root,COG3835@2|Bacteria,1NJZ9@1224|Proteobacteria,1RMEP@1236|Gammaproteobacteria,1XTZT@135623|Vibrionales	135623|Vibrionales	KT	COG3835 Sugar diacid utilization regulator	cdaR	-	-	ko:K02647	-	-	-	-	ko00000,ko03000	-	-	-	Diacid_rec,HTH_30
k141_3527_99	357804.Ping_2639	1.67e-63	198.0	COG4088@1|root,COG4088@2|Bacteria,1QZBT@1224|Proteobacteria,1T44Z@1236|Gammaproteobacteria	1236|Gammaproteobacteria	F	Chromatin associated protein KTI12	-	-	-	-	-	-	-	-	-	-	-	-	AAA_33
k141_3527_100	1449050.JNLE01000003_gene1885	7.4e-21	88.2	COG0645@1|root,COG0645@2|Bacteria,1V3DI@1239|Firmicutes,24CM6@186801|Clostridia,36I0T@31979|Clostridiaceae	186801|Clostridia	S	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_33
k141_3527_101	675806.VII_000384	1.79e-29	109.0	COG1664@1|root,COG1664@2|Bacteria,1MZG6@1224|Proteobacteria,1SE1C@1236|Gammaproteobacteria,1XYDY@135623|Vibrionales	135623|Vibrionales	M	Polymer-forming cytoskeletal	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
k141_3527_102	55601.VANGNB10_cII0027c	7.83e-153	437.0	COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,1RMIR@1236|Gammaproteobacteria,1XTK9@135623|Vibrionales	135623|Vibrionales	M	COG0739 Membrane proteins related to metalloendopeptidases	tagE	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
k141_2444_1	1504672.669783588	1.44e-35	150.0	COG2931@1|root,COG3210@1|root,COG4625@1|root,COG2931@2|Bacteria,COG3210@2|Bacteria,COG4625@2|Bacteria,1MU7T@1224|Proteobacteria	1224|Proteobacteria	Q	COG2931, RTX toxins and related Ca2 -binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	DUF4347,DUF5122,HemolysinCabind,Lactonase,Laminin_G_3,Peptidase_M10_C,W_rich_C
k141_5174_1	485918.Cpin_2398	6.24e-24	109.0	COG0454@1|root,COG0456@2|Bacteria,4NFWE@976|Bacteroidetes,1IPDZ@117747|Sphingobacteriia	976|Bacteroidetes	K	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
k141_5174_2	1396141.BATP01000007_gene5521	3.56e-58	209.0	COG0318@1|root,COG0318@2|Bacteria,46XHF@74201|Verrucomicrobia,2IVXI@203494|Verrucomicrobiae	203494|Verrucomicrobiae	IQ	AMP-binding enzyme	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding
k141_4909_1	1348635.BBJY01000005_gene3359	0.0	1686.0	COG0582@1|root,COG0582@2|Bacteria,1RF3K@1224|Proteobacteria,1S5K8@1236|Gammaproteobacteria,1XW6R@135623|Vibrionales	135623|Vibrionales	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
k141_4909_2	1348635.BBJY01000005_gene3358	1.73e-101	317.0	COG0582@1|root,COG0582@2|Bacteria,1N7DP@1224|Proteobacteria,1TCIH@1236|Gammaproteobacteria,1XWQY@135623|Vibrionales	135623|Vibrionales	L	viral genome integration into host DNA	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_4909_3	617140.AJZE01000137_gene1951	2.86e-33	134.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,1XUGQ@135623|Vibrionales	135623|Vibrionales	NT	methyl-accepting chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal,dCache_1
k141_4909_4	1188252.AJYK01000114_gene1601	6.94e-94	277.0	COG5631@1|root,COG5631@2|Bacteria,1RDM3@1224|Proteobacteria,1S11S@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	transcription regulator, contains HTH domain (MarR family)	-	-	-	-	-	-	-	-	-	-	-	-	HTH_27
k141_4909_5	1188252.AJYK01000114_gene1600	4.96e-245	688.0	COG1593@1|root,COG3090@1|root,COG1593@2|Bacteria,COG3090@2|Bacteria,1MU0F@1224|Proteobacteria,1RNAM@1236|Gammaproteobacteria,1XUEZ@135623|Vibrionales	135623|Vibrionales	G	Tripartite ATP-independent periplasmic transporter, DctM component	-	-	-	-	-	-	-	-	-	-	-	-	DctM
k141_4909_6	1188252.AJYK01000114_gene1600	6.62e-60	204.0	COG1593@1|root,COG3090@1|root,COG1593@2|Bacteria,COG3090@2|Bacteria,1MU0F@1224|Proteobacteria,1RNAM@1236|Gammaproteobacteria,1XUEZ@135623|Vibrionales	135623|Vibrionales	G	Tripartite ATP-independent periplasmic transporter, DctM component	-	-	-	-	-	-	-	-	-	-	-	-	DctM
k141_4909_7	1188252.AJYK01000114_gene1599	2.78e-169	481.0	COG1638@1|root,COG1638@2|Bacteria,1MVYB@1224|Proteobacteria,1RQG9@1236|Gammaproteobacteria,1XW0B@135623|Vibrionales	135623|Vibrionales	G	Bacterial extracellular solute-binding protein, family 7	-	-	-	-	-	-	-	-	-	-	-	-	DctP
k141_4909_8	1188252.AJYK01000114_gene1598	2.79e-117	342.0	COG1540@1|root,COG1540@2|Bacteria,1MUYV@1224|Proteobacteria,1RSCZ@1236|Gammaproteobacteria,1XV4U@135623|Vibrionales	135623|Vibrionales	S	Belongs to the UPF0271 (lamB) family	-	-	-	ko:K07160	-	-	-	-	ko00000	-	-	-	LamB_YcsF
k141_4909_9	1348635.BBJY01000005_gene3352	6.56e-101	298.0	COG2049@1|root,COG2049@2|Bacteria,1MWRB@1224|Proteobacteria,1RQIQ@1236|Gammaproteobacteria,1XX9Y@135623|Vibrionales	135623|Vibrionales	E	Allophanate hydrolase, subunit 1	-	-	-	-	-	-	-	-	-	-	-	-	CT_C_D
k141_4909_10	1348635.BBJY01000005_gene3351	2.46e-152	436.0	COG1984@1|root,COG1984@2|Bacteria,1MU9H@1224|Proteobacteria,1RR39@1236|Gammaproteobacteria,1XTJ1@135623|Vibrionales	135623|Vibrionales	E	Allophanate hydrolase subunit 2	-	-	-	-	-	-	-	-	-	-	-	-	CT_A_B
k141_4909_12	159749.K0R054	8.74e-19	90.5	COG1814@1|root,KOG4473@2759|Eukaryota,2XC42@2836|Bacillariophyta	2836|Bacillariophyta	S	VIT family	-	-	-	-	-	-	-	-	-	-	-	-	VIT1
k141_4909_13	1051646.VITU9109_09307	4.21e-151	435.0	COG1609@1|root,COG1609@2|Bacteria,1MUEP@1224|Proteobacteria,1RR6G@1236|Gammaproteobacteria,1XWUQ@135623|Vibrionales	135623|Vibrionales	K	helix_turn _helix lactose operon repressor	-	-	-	ko:K06145	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
k141_4732_3	675806.VII_001680	1.45e-27	104.0	2E37U@1|root,32Y7H@2|Bacteria,1N8JQ@1224|Proteobacteria,1SCAH@1236|Gammaproteobacteria,1XYDU@135623|Vibrionales	135623|Vibrionales	S	Protein of unknown function (DUF2956)	VC2147	-	-	-	-	-	-	-	-	-	-	-	DUF2956
k141_2025_1	765911.Thivi_0027	9.53e-53	187.0	COG2995@1|root,COG2995@2|Bacteria,1MWG1@1224|Proteobacteria,1RM9Z@1236|Gammaproteobacteria,1WX87@135613|Chromatiales	135613|Chromatiales	S	PFAM Paraquat-inducible protein A	-	-	-	ko:K03808	-	-	-	-	ko00000	-	-	-	PqiA
k141_2610_2	626418.bglu_2g10060	4.06e-30	117.0	COG3509@1|root,COG3509@2|Bacteria,1NTIV@1224|Proteobacteria,2VKDX@28216|Betaproteobacteria,1K7GS@119060|Burkholderiaceae	28216|Betaproteobacteria	Q	depolymerase	-	-	3.1.1.75	ko:K05973	ko00650,map00650	-	R05118	-	ko00000,ko00001,ko01000	-	-	-	Esterase_phd
k141_5011_1	1305732.JAGG01000001_gene406	8.32e-16	80.5	COG0404@1|root,COG0404@2|Bacteria,2GJ47@201174|Actinobacteria,4FKQ2@85023|Microbacteriaceae	201174|Actinobacteria	E	The glycine cleavage system catalyzes the degradation of glycine	gcvT	-	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
k141_5011_2	273116.14324271	2.06e-21	94.7	COG0404@1|root,arCOG00756@2157|Archaea,2XU1F@28890|Euryarchaeota,241ZF@183967|Thermoplasmata	183967|Thermoplasmata	H	Aminomethyltransferase folate-binding domain	-	-	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
k141_5011_3	1134413.ANNK01000031_gene1437	3.29e-18	83.2	COG1522@1|root,COG1522@2|Bacteria,1V72S@1239|Firmicutes,4HJS3@91061|Bacilli,1ZGCT@1386|Bacillus	91061|Bacilli	K	helix_turn_helix ASNC type	-	-	-	ko:K03718	-	-	-	-	ko00000,ko03000	-	-	-	AsnC_trans_reg,HTH_24,HTH_AsnC-type
k141_5011_4	177439.DP0303	4.34e-38	142.0	COG1249@1|root,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,42N8Y@68525|delta/epsilon subdivisions,2WIR7@28221|Deltaproteobacteria,2MHP6@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM Pyridine nucleotide-disulphide oxidoreductase, FAD NAD(P)-binding domain, pyridine nucleotide-disulfide oxidoreductase dimerization region, FAD-dependent pyridine nucleotide-disulfide oxidoreductase	lpdA	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
k141_4328_2	1219077.VAZ01S_016_00510	1.63e-162	494.0	COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,1MUKF@1224|Proteobacteria,1RMW6@1236|Gammaproteobacteria,1XVBD@135623|Vibrionales	135623|Vibrionales	S	membrane metal-binding protein	-	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131,Lactamase_B
k141_4328_4	675806.VII_001968	3e-180	515.0	COG4591@1|root,COG4591@2|Bacteria,1MVV7@1224|Proteobacteria,1RMP9@1236|Gammaproteobacteria,1XSJ2@135623|Vibrionales	135623|Vibrionales	M	COG4591 ABC-type transport system, involved in lipoprotein release, permease component	lolE	-	-	ko:K09808	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125	-	-	FtsX,MacB_PCD
k141_4328_5	55601.VANGNB10_cI1708c	1.14e-107	316.0	COG1136@1|root,COG1136@2|Bacteria,1MVSQ@1224|Proteobacteria,1RMWK@1236|Gammaproteobacteria,1XTZP@135623|Vibrionales	135623|Vibrionales	V	Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner	lolD	GO:0003674,GO:0003824,GO:0005215,GO:0006810,GO:0008150,GO:0015399,GO:0015405,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0042623,GO:0042626,GO:0043492,GO:0051179,GO:0051234,GO:0055085	-	ko:K09810	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.125	-	-	ABC_tran
k141_4328_6	1517681.HW45_22095	2.12e-18	84.3	COG4591@1|root,COG4591@2|Bacteria,1MVV7@1224|Proteobacteria,1RMP9@1236|Gammaproteobacteria,1XSMT@135623|Vibrionales	135623|Vibrionales	M	COG4591 ABC-type transport system, involved in lipoprotein release, permease component	lolC	-	-	ko:K09808	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125	-	-	FtsX,MacB_PCD
k141_1574_2	1238450.VIBNISOn1_1670023	4.22e-167	471.0	COG3833@1|root,COG3833@2|Bacteria,1QA3Z@1224|Proteobacteria,1RQ00@1236|Gammaproteobacteria,1XW8X@135623|Vibrionales	135623|Vibrionales	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K15772	ko02010,map02010	M00491	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.16,3.A.1.1.2	-	-	BPD_transp_1
k141_1574_3	1238450.VIBNISOn1_1670025	8.74e-207	580.0	COG1175@1|root,COG1175@2|Bacteria,1MXKR@1224|Proteobacteria,1RN6B@1236|Gammaproteobacteria,1XVI9@135623|Vibrionales	135623|Vibrionales	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K15771	ko02010,map02010	M00491	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.16,3.A.1.1.2	-	-	BPD_transp_1
k141_2368_1	94122.Shewana3_3456	4.55e-96	295.0	COG0845@1|root,COG0845@2|Bacteria,1MU8D@1224|Proteobacteria,1RN0E@1236|Gammaproteobacteria,2QAVB@267890|Shewanellaceae	1236|Gammaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	macA	-	-	ko:K02005,ko:K13888	-	M00709	-	-	ko00000,ko00002,ko02000	8.A.1	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
k141_2368_2	1348635.BBJY01000015_gene705	5.82e-300	836.0	COG0577@1|root,COG1136@1|root,COG0577@2|Bacteria,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,1RNUJ@1236|Gammaproteobacteria,1XSYR@135623|Vibrionales	135623|Vibrionales	V	Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides	macB	-	-	ko:K05685	ko02010,map02010	M00709	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.122.1,3.A.1.122.12	-	-	ABC_tran,FtsX,MacB_PCD
k141_2368_3	1515746.HR45_18390	5.83e-201	571.0	COG1538@1|root,COG1538@2|Bacteria,1MUA8@1224|Proteobacteria,1RN0I@1236|Gammaproteobacteria,2QENS@267890|Shewanellaceae	1236|Gammaproteobacteria	MU	Outer membrane efflux protein	Z012_07725	-	-	-	-	-	-	-	-	-	-	-	OEP
k141_2368_4	998674.ATTE01000001_gene2944	5.44e-85	257.0	COG1280@1|root,COG1280@2|Bacteria,1Q4CV@1224|Proteobacteria,1RQV8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Lysine exporter protein (LYSE YGGA)	-	-	-	ko:K05834	-	-	-	-	ko00000,ko02000	2.A.76.1.1	-	-	LysE
k141_2368_5	1226325.HMPREF1548_00875	0.000313	47.4	COG2731@1|root,COG2731@2|Bacteria,1VCI9@1239|Firmicutes,24QNC@186801|Clostridia,36NJ1@31979|Clostridiaceae	186801|Clostridia	G	protein, YhcH YjgK YiaL family	-	-	-	-	-	-	-	-	-	-	-	-	DUF386
k141_928_1	1238450.VIBNISOn1_1610077	9.48e-272	763.0	COG0514@1|root,COG0514@2|Bacteria,1MVGG@1224|Proteobacteria,1RS89@1236|Gammaproteobacteria,1XT65@135623|Vibrionales	135623|Vibrionales	L	COG0514 Superfamily II DNA helicase	-	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecQ_Zn_bind
k141_928_2	1116375.VEJY3_07515	7.23e-74	222.0	arCOG12631@1|root,3172B@2|Bacteria,1RH7M@1224|Proteobacteria,1S7HJ@1236|Gammaproteobacteria,1Y2DF@135623|Vibrionales	135623|Vibrionales	S	Bacterial PH domain	-	-	-	-	-	-	-	-	-	-	-	-	bPH_1
k141_928_4	948565.AFFP02000001_gene819	5.24e-146	422.0	COG1609@1|root,COG1609@2|Bacteria,1MUEP@1224|Proteobacteria,1RQKH@1236|Gammaproteobacteria,1Y7RA@135625|Pasteurellales	135625|Pasteurellales	K	HTH-type transcriptional regulator gntR of Bacteria UniRef RepID GNTR_ECOL6	gntR	-	-	ko:K06145	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_1,Peripla_BP_3
k141_928_5	326442.PSHAb0479	3.72e-247	687.0	COG2610@1|root,COG2610@2|Bacteria,1MUFG@1224|Proteobacteria,1RNGE@1236|Gammaproteobacteria,2Q1FH@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	EG	GntP family permease	gntU	GO:0003674,GO:0005215,GO:0005402,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008324,GO:0008643,GO:0015075,GO:0015144,GO:0015291,GO:0015293,GO:0015294,GO:0015318,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0034219,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098655	-	ko:K03299,ko:K06156	-	-	-	-	ko00000,ko02000	2.A.8,2.A.8.1.8	-	iAF1260.b4476,iB21_1397.B21_03240,iBWG_1329.BWG_3127,iEC55989_1330.EC55989_3845,iECB_1328.ECB_03287,iECDH10B_1368.ECDH10B_3609,iECDH1ME8569_1439.ECDH1ME8569_3313,iECD_1391.ECD_03287,iECH74115_1262.ECH74115_4752,iECIAI1_1343.ECIAI1_3581,iECIAI39_1322.ECIAI39_3918,iECO26_1355.ECO26_4525,iECSE_1348.ECSE_3704,iECSP_1301.ECSP_4391,iECUMN_1333.ECUMN_3899,iECs_1301.ECs4285,iEKO11_1354.EKO11_0306,iETEC_1333.ETEC_3684,iEcDH1_1363.EcDH1_0279,iEcE24377_1341.EcE24377A_3914,iEcHS_1320.EcHS_A3635,iEcSMS35_1347.EcSMS35_3719,iEcolC_1368.EcolC_0277,iG2583_1286.G2583_4138,iJO1366.b4476,iSDY_1059.SDY_3587,iUMNK88_1353.UMNK88_4205,iY75_1357.Y75_RS20045,iYL1228.KPN_03800,iZ_1308.Z4804	GntP_permease
k141_928_6	104623.Ser39006_00204	1.36e-77	236.0	COG3265@1|root,COG3265@2|Bacteria,1RHD0@1224|Proteobacteria,1S2UE@1236|Gammaproteobacteria,405KF@613|Serratia	1236|Gammaproteobacteria	F	Adenylylsulphate kinase	idnK	GO:0003674,GO:0003824,GO:0005975,GO:0006082,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016052,GO:0016054,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019520,GO:0019521,GO:0019523,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044275,GO:0044281,GO:0044282,GO:0046176,GO:0046183,GO:0046316,GO:0046395,GO:0071704,GO:0072329,GO:1901575	2.7.1.12	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	-	R01737	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	iECSF_1327.ECSF_4156	SKI
k141_928_7	1283284.AZUK01000001_gene2242	2.32e-97	302.0	COG0129@1|root,COG0129@2|Bacteria,1MU3T@1224|Proteobacteria,1RMNA@1236|Gammaproteobacteria,1Y3I8@135624|Aeromonadales	135624|Aeromonadales	EG	Belongs to the IlvD Edd family	edd	-	4.2.1.12	ko:K01690	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00008	R02036	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
k141_4329_2	765913.ThidrDRAFT_4315	5.37e-129	379.0	COG1171@1|root,COG1171@2|Bacteria,1MVWJ@1224|Proteobacteria,1RMY6@1236|Gammaproteobacteria,1WWPJ@135613|Chromatiales	1236|Gammaproteobacteria	E	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA	tdcB	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
k141_4329_3	314292.VAS14_21252	3.98e-21	93.6	COG1167@1|root,COG1167@2|Bacteria,1MUJE@1224|Proteobacteria,1RXYA@1236|Gammaproteobacteria,1XVSK@135623|Vibrionales	135623|Vibrionales	K	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2,GntR
k141_2026_1	1348635.BBJY01000001_gene2342	2.46e-166	481.0	28JFR@1|root,2Z99N@2|Bacteria,1R7C5@1224|Proteobacteria,1RZYU@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_2026_2	1219077.VAZ01S_149_00010	4.48e-116	343.0	COG0697@1|root,COG0697@2|Bacteria,1MVGC@1224|Proteobacteria,1RMXB@1236|Gammaproteobacteria,1XT7G@135623|Vibrionales	135623|Vibrionales	EG	of the drug metabolite transporter (DMT) superfamily	yddG	-	-	-	-	-	-	-	-	-	-	-	EamA
k141_2369_1	714943.Mucpa_5856	1.51e-23	96.7	COG4302@1|root,COG4302@2|Bacteria,4NH0M@976|Bacteroidetes,1IVB8@117747|Sphingobacteriia	976|Bacteroidetes	H	PFAM Ethanolamine ammonia-lyase light chain	eutC	-	4.3.1.7	ko:K03736	ko00564,ko01100,map00564,map01100	-	R00749	RC00370	ko00000,ko00001,ko01000	-	-	-	EutC
k141_2369_2	1191523.MROS_1928	2.32e-72	236.0	COG2509@1|root,COG2509@2|Bacteria	2|Bacteria	H	5-formyltetrahydrofolate cyclo-ligase activity	IV02_08645	-	-	ko:K07137	-	-	-	-	ko00000	-	-	-	FAD_binding_2,HI0933_like,Pyr_redox_2
k141_4025_1	96561.Dole_0130	1.42e-64	206.0	COG0785@1|root,COG0785@2|Bacteria,1RCP7@1224|Proteobacteria,42Q7J@68525|delta/epsilon subdivisions,2WJCK@28221|Deltaproteobacteria,2MIR8@213118|Desulfobacterales	28221|Deltaproteobacteria	O	PFAM Cytochrome C biogenesis protein transmembrane region	ccdA	-	-	ko:K06196	-	-	-	-	ko00000,ko02000	5.A.1.2	-	-	DsbD,Thioredoxin
k141_4025_2	1265505.ATUG01000001_gene4461	1.11e-135	401.0	COG0477@1|root,COG2814@2|Bacteria,1MVSH@1224|Proteobacteria,42NA4@68525|delta/epsilon subdivisions,2WKTU@28221|Deltaproteobacteria,2MHYA@213118|Desulfobacterales	28221|Deltaproteobacteria	EGP	PFAM Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_1_like,MFS_3,Sugar_tr
k141_4025_3	1304885.AUEY01000024_gene2718	7.5e-117	341.0	COG1024@1|root,COG1024@2|Bacteria,1MXHV@1224|Proteobacteria,42QU2@68525|delta/epsilon subdivisions,2WMSF@28221|Deltaproteobacteria,2MJJF@213118|Desulfobacterales	28221|Deltaproteobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
k141_4025_4	1121935.AQXX01000144_gene4523	5.44e-48	157.0	2DHXS@1|root,32U9Z@2|Bacteria,1N3G8@1224|Proteobacteria,1SASY@1236|Gammaproteobacteria,1XKR1@135619|Oceanospirillales	135619|Oceanospirillales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_2924_3	945543.VIBR0546_06342	3.04e-161	473.0	COG3456@1|root,COG3456@2|Bacteria,1MUKE@1224|Proteobacteria,1RQGW@1236|Gammaproteobacteria,1XUQ5@135623|Vibrionales	135623|Vibrionales	T	conserved protein, contains FHA domain	-	-	-	ko:K11894	-	-	-	-	ko00000,ko02044	3.A.23.1	-	-	FHA
k141_2924_4	345073.VC395_A0104	4.01e-148	427.0	COG3520@1|root,COG3520@2|Bacteria,1MWVS@1224|Proteobacteria,1RQD5@1236|Gammaproteobacteria,1XT7D@135623|Vibrionales	135623|Vibrionales	S	protein conserved in bacteria	-	-	-	ko:K11895	ko02025,map02025	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	T6SS_TssG
k141_2924_5	55601.VANGNB10_cII0073	0.0	889.0	COG3519@1|root,COG3519@2|Bacteria,1MUY4@1224|Proteobacteria,1RPK4@1236|Gammaproteobacteria,1XTN2@135623|Vibrionales	135623|Vibrionales	S	protein conserved in bacteria	vasA	-	-	ko:K11896	-	M00334	-	-	ko00000,ko00002,ko02044	3.A.23.1	-	-	T6SS_TssF
k141_2370_1	1121396.KB893056_gene2667	2.14e-122	370.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,42M51@68525|delta/epsilon subdivisions,2WIPP@28221|Deltaproteobacteria,2MI4H@213118|Desulfobacterales	28221|Deltaproteobacteria	NU	TIGRFAM type IV-A pilus assembly ATPase PilB	pilB	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE,T2SSE_N,cNMP_binding
k141_4735_1	1280001.BAOA01000047_gene1761	3.82e-97	289.0	COG0190@1|root,COG0190@2|Bacteria,1MWU4@1224|Proteobacteria,1RNSW@1236|Gammaproteobacteria,1XTV0@135623|Vibrionales	135623|Vibrionales	F	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	GO:0003674,GO:0003824,GO:0004477,GO:0004486,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0019752,GO:0034641,GO:0042558,GO:0043436,GO:0043603,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0055114,GO:0071704,GO:1901360,GO:1901564	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
k141_4735_2	1249627.D779_3409	3.61e-62	199.0	296ZZ@1|root,2ZU8H@2|Bacteria,1RED2@1224|Proteobacteria,1S5WC@1236|Gammaproteobacteria,1WYTA@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_5012_1	999411.HMPREF1092_01944	1.45e-07	53.9	COG0642@1|root,COG2205@2|Bacteria,1TQMV@1239|Firmicutes,247SE@186801|Clostridia,36EKZ@31979|Clostridiaceae	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,Hpt,PAS_3,PAS_9,Response_reg,SBP_bac_3,dCache_1,sCache_3_3
k141_5012_2	794903.OPIT5_15125	1.53e-77	240.0	COG0745@1|root,COG0745@2|Bacteria,46VWY@74201|Verrucomicrobia,3K7WH@414999|Opitutae	414999|Opitutae	K	Two component transcriptional regulator, winged helix family	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
k141_5054_1	95619.PM1_0220955	2.16e-14	73.9	COG0598@1|root,COG0598@2|Bacteria,1MW8W@1224|Proteobacteria,1RRTZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	Zinc transport protein zntB	zntB	GO:0000041,GO:0003674,GO:0005215,GO:0005385,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006829,GO:0008150,GO:0008324,GO:0015075,GO:0015318,GO:0015562,GO:0016020,GO:0016021,GO:0022857,GO:0022883,GO:0022890,GO:0030001,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0046583,GO:0046873,GO:0046915,GO:0051179,GO:0051234,GO:0055085,GO:0070838,GO:0071577,GO:0071944,GO:0072509,GO:0072511,GO:0098655,GO:0098660,GO:0098662	-	ko:K16074	-	-	-	-	ko00000,ko02000	1.A.35.4	-	-	CorA
k141_5054_2	1279015.KB908456_gene1709	3.27e-112	335.0	COG0530@1|root,COG0530@2|Bacteria,1MU3R@1224|Proteobacteria,1RMRD@1236|Gammaproteobacteria,1Y40H@135624|Aeromonadales	135624|Aeromonadales	P	COG0530 Ca2 Na antiporter	-	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
k141_5054_3	1121396.KB893126_gene10	2.31e-89	306.0	COG1196@1|root,COG1196@2|Bacteria,1R6NJ@1224|Proteobacteria,42WEE@68525|delta/epsilon subdivisions,2WS7W@28221|Deltaproteobacteria,2MM30@213118|Desulfobacterales	28221|Deltaproteobacteria	D	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_1607_3	375286.mma_2529	3.58e-07	58.5	2AQWX@1|root,31G5F@2|Bacteria,1N36S@1224|Proteobacteria,2VSN8@28216|Betaproteobacteria	28216|Betaproteobacteria	S	PFAM Relaxase mobilization nuclease family protein	-	-	-	-	-	-	-	-	-	-	-	-	Relaxase
k141_1607_4	1051646.VITU9109_00560	3.96e-14	78.2	COG0582@1|root,COG0582@2|Bacteria,1N73Z@1224|Proteobacteria,1SEHI@1236|Gammaproteobacteria,1XTD7@135623|Vibrionales	135623|Vibrionales	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
k141_4037_1	56107.Cylst_6227	5.19e-107	358.0	COG0604@1|root,COG3321@1|root,COG0604@2|Bacteria,COG3321@2|Bacteria,1FZXE@1117|Cyanobacteria,1HIGN@1161|Nostocales	1117|Cyanobacteria	CQ	acyl transferase domain	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N,ADH_zinc_N_2,AMP-binding,Acyl_transf_1,Aminotran_1_2,KAsynt_C_assoc,KR,Ketoacyl-synt_C,PP-binding,PS-DH,ketoacyl-synt
k141_946_1	983545.Glaag_0813	9.6e-60	220.0	COG2982@1|root,COG2982@2|Bacteria,1MUME@1224|Proteobacteria,1RNPC@1236|Gammaproteobacteria,464KK@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	Domain of Unknown Function (DUF748)	-	-	-	-	-	-	-	-	-	-	-	-	DUF748,OmpA
k141_946_2	1188252.AJYK01000062_gene1905	3.3e-163	499.0	COG2982@1|root,COG2982@2|Bacteria,1MUME@1224|Proteobacteria,1RNPC@1236|Gammaproteobacteria,1XSPR@135623|Vibrionales	135623|Vibrionales	M	Domain of Unknown Function (DUF748)	-	-	-	-	-	-	-	-	-	-	-	-	DUF748
k141_946_3	29495.EA26_10275	5.06e-57	183.0	COG3658@1|root,COG3658@2|Bacteria,1RB03@1224|Proteobacteria,1S9SA@1236|Gammaproteobacteria,1XVCJ@135623|Vibrionales	135623|Vibrionales	C	Prokaryotic cytochrome b561	-	-	-	-	-	-	-	-	-	-	-	-	Ni_hydr_CYTB
k141_946_4	870967.VIS19158_21768	3.23e-106	328.0	COG2194@1|root,COG2194@2|Bacteria,1MWS7@1224|Proteobacteria,1RMNG@1236|Gammaproteobacteria,1XSQM@135623|Vibrionales	135623|Vibrionales	S	membrane-associated, metal-dependent hydrolase	eptA	-	2.7.8.43	ko:K03760	ko01503,map01503	M00722	R11555,R11556,R11557	RC00002	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	DUF1705,Sulfatase
k141_4038_1	1304885.AUEY01000029_gene2496	3.94e-56	190.0	COG0655@1|root,COG2249@1|root,COG0655@2|Bacteria,COG2249@2|Bacteria,1NSWP@1224|Proteobacteria,42YGD@68525|delta/epsilon subdivisions,2WUF0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Flavodoxin-like fold	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
k141_4039_1	55601.VANGNB10_67p033c	6.39e-161	454.0	COG3039@1|root,COG3039@2|Bacteria,1MXTN@1224|Proteobacteria,1RM94@1236|Gammaproteobacteria,1XVGA@135623|Vibrionales	135623|Vibrionales	L	User locus_tag	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_5
k141_2632_1	1116375.VEJY3_21651	9.88e-55	183.0	COG0055@1|root,COG0055@2|Bacteria,1N6UZ@1224|Proteobacteria,1RNQW@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	-	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
k141_2632_2	1116375.VEJY3_21646	4.02e-73	221.0	COG0355@1|root,COG0355@2|Bacteria,1N1NE@1224|Proteobacteria,1S9B5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	epsilon subunit	-	-	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_DE_N
k141_2632_3	1116375.VEJY3_21641	1.1e-47	153.0	2E70X@1|root,331JP@2|Bacteria,1N81S@1224|Proteobacteria,1SCI0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter	-	-	-	ko:K02116	-	-	-	-	ko00000,ko00194	3.A.2.1	-	-	ATPase_gene1
k141_2632_4	1116375.VEJY3_21636	1.98e-123	355.0	COG0356@1|root,COG0356@2|Bacteria,1RBEV@1224|Proteobacteria,1T170@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	it plays a direct role in the translocation of protons across the membrane	-	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
k141_2632_5	1415778.JQMM01000001_gene2179	1.52e-35	122.0	COG0636@1|root,COG0636@2|Bacteria,1NAIE@1224|Proteobacteria,1SA80@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	-	-	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
k141_2632_6	1116375.VEJY3_21626	9.72e-130	374.0	COG0711@1|root,COG0711@2|Bacteria,1R6C0@1224|Proteobacteria,1S4NA@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	-	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B,OSCP
k141_2632_7	1116375.VEJY3_21621	0.0	875.0	COG0056@1|root,COG0056@2|Bacteria,1MUG7@1224|Proteobacteria,1RP4V@1236|Gammaproteobacteria,1XU3H@135623|Vibrionales	135623|Vibrionales	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	-	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
k141_2632_8	1116375.VEJY3_21616	9.1e-70	218.0	COG0224@1|root,COG0224@2|Bacteria,1RIE5@1224|Proteobacteria,1S3ZW@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	ATP synthase gamma subunit	-	-	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
k141_1609_1	1232437.KL662020_gene642	1.67e-23	93.6	COG1522@1|root,COG1522@2|Bacteria,1RIKY@1224|Proteobacteria,42RM4@68525|delta/epsilon subdivisions,2WNU8@28221|Deltaproteobacteria,2MJYM@213118|Desulfobacterales	28221|Deltaproteobacteria	K	AsnC-type helix-turn-helix domain	nirD	-	-	-	-	-	-	-	-	-	-	-	HTH_AsnC-type
k141_1609_2	56780.SYN_00473	6.01e-55	175.0	COG0432@1|root,COG0432@2|Bacteria,1RH13@1224|Proteobacteria,42TJK@68525|delta/epsilon subdivisions,2WQ0Z@28221|Deltaproteobacteria,2MRWJ@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Uncharacterised protein family UPF0047	-	-	-	-	-	-	-	-	-	-	-	-	UPF0047
k141_1609_3	1121438.JNJA01000005_gene1125	1.25e-30	109.0	COG2920@1|root,COG2920@2|Bacteria,1RGVG@1224|Proteobacteria,42SN5@68525|delta/epsilon subdivisions,2WP28@28221|Deltaproteobacteria,2MBHY@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	sulfur relay protein, TusE DsrC DsvC family	dsrC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K11179	ko04122,map04122	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	DsrC
k141_4040_1	335543.Sfum_2845	1.67e-60	198.0	COG1073@1|root,COG1073@2|Bacteria,1RBV1@1224|Proteobacteria,42M9M@68525|delta/epsilon subdivisions,2WM64@28221|Deltaproteobacteria,2MQDT@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Serine aminopeptidase, S33	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Hydrolase_4
k141_5058_1	177437.HRM2_19510	6.27e-141	430.0	COG0610@1|root,COG0610@2|Bacteria,1MU96@1224|Proteobacteria,42M86@68525|delta/epsilon subdivisions,2WIT1@28221|Deltaproteobacteria,2MHMG@213118|Desulfobacterales	28221|Deltaproteobacteria	L	Subunit R is required for both nuclease and ATPase activities, but not for modification	hsdR	-	3.1.21.3	ko:K01153	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	DUF3387,HSDR_N,ResIII
k141_2633_1	56780.SYN_00572	2.36e-19	85.1	COG0424@1|root,COG0424@2|Bacteria,1RH6H@1224|Proteobacteria,42SR7@68525|delta/epsilon subdivisions,2WP65@28221|Deltaproteobacteria,2MRSJ@213462|Syntrophobacterales	28221|Deltaproteobacteria	D	Maf-like protein	maf	-	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
k141_2633_2	1265505.ATUG01000003_gene406	1.67e-66	212.0	COG0325@1|root,COG0325@2|Bacteria,1MWN7@1224|Proteobacteria,42PSG@68525|delta/epsilon subdivisions,2WKYN@28221|Deltaproteobacteria,2MJ9P@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis	yggS	-	-	ko:K06997	-	-	-	-	ko00000	-	-	-	Ala_racemase_N
k141_2633_3	879212.DespoDRAFT_02157	9.64e-66	204.0	COG1636@1|root,COG1636@2|Bacteria,1MUG5@1224|Proteobacteria,42M1E@68525|delta/epsilon subdivisions,2WMR5@28221|Deltaproteobacteria,2MJG7@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)	queH	-	1.17.99.6	ko:K09765	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF208
k141_4041_1	1408428.JNJP01000006_gene2559	3.85e-54	175.0	COG0563@1|root,COG0563@2|Bacteria,1MXCZ@1224|Proteobacteria,42M8E@68525|delta/epsilon subdivisions,2WJH0@28221|Deltaproteobacteria,2M80C@213115|Desulfovibrionales	28221|Deltaproteobacteria	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK,ATP_bind_3
k141_4041_2	96561.Dole_0468	5.15e-21	84.7	COG0828@1|root,COG0828@2|Bacteria,1Q45R@1224|Proteobacteria,42VJ6@68525|delta/epsilon subdivisions,2WR6Z@28221|Deltaproteobacteria,2MM0Q@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Belongs to the bacterial ribosomal protein bS21 family	rpsU	-	-	ko:K02970	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S21
k141_4041_3	1270196.JCKI01000010_gene861	2.46e-62	210.0	COG0285@1|root,COG0285@2|Bacteria,4NES8@976|Bacteroidetes,1IQU2@117747|Sphingobacteriia	976|Bacteroidetes	H	Belongs to the folylpolyglutamate synthase family	folC	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_M
k141_1610_1	1121396.KB892900_gene2109	8.94e-187	548.0	COG3829@1|root,COG3829@2|Bacteria,1N4M6@1224|Proteobacteria,42M38@68525|delta/epsilon subdivisions,2WIR0@28221|Deltaproteobacteria,2MJ85@213118|Desulfobacterales	28221|Deltaproteobacteria	T	sigma-54 factor interaction domain-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,PAS_4,PAS_9,Sigma54_activat
k141_2634_1	675815.VOA_000454	7.67e-134	395.0	COG1305@1|root,COG1305@2|Bacteria,1MVV3@1224|Proteobacteria,1RRIA@1236|Gammaproteobacteria,1XSMI@135623|Vibrionales	135623|Vibrionales	E	7 transmembrane helices usually fused to an inactive transglutaminase	-	-	-	-	-	-	-	-	-	-	-	-	7TM_transglut,Transglut_i_TM
k141_1352_1	675806.VII_002423	3.13e-60	196.0	COG0715@1|root,COG0715@2|Bacteria,1REGQ@1224|Proteobacteria,1S58R@1236|Gammaproteobacteria,1XUZJ@135623|Vibrionales	135623|Vibrionales	P	ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic	-	-	-	-	-	-	-	-	-	-	-	-	NMT1
k141_1352_2	55601.VANGNB10_cI1579c	3.32e-92	292.0	COG2199@1|root,COG2199@2|Bacteria,1RBYX@1224|Proteobacteria,1S2VI@1236|Gammaproteobacteria,1Y2FA@135623|Vibrionales	135623|Vibrionales	T	Diguanylate cyclase, GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
k141_1352_3	1187848.AJYQ01000090_gene2804	5.92e-67	215.0	COG2200@1|root,COG2200@2|Bacteria,1N50H@1224|Proteobacteria,1SYN8@1236|Gammaproteobacteria,1XUYQ@135623|Vibrionales	135623|Vibrionales	T	COG2200 FOG EAL domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL
k141_1352_4	1187848.AJYQ01000090_gene2806	4.45e-97	288.0	2AVVY@1|root,31MPS@2|Bacteria,1QJH3@1224|Proteobacteria,1THGW@1236|Gammaproteobacteria,1XVRR@135623|Vibrionales	135623|Vibrionales	-	-	VCA0537	-	-	-	-	-	-	-	-	-	-	-	-
k141_1352_5	29495.EA26_11665	1.47e-139	409.0	COG0517@1|root,COG2116@1|root,COG0517@2|Bacteria,COG2116@2|Bacteria,1MU0W@1224|Proteobacteria,1RQ6K@1236|Gammaproteobacteria,1XUCS@135623|Vibrionales	135623|Vibrionales	P	COG2116 Formate nitrite family of transporters	VVA0737	-	-	ko:K06212	-	-	-	-	ko00000,ko02000	1.A.16.1.1,1.A.16.1.3	-	-	CBS,Form_Nir_trans
k141_5060_1	1249480.B649_07035	1.51e-19	97.8	COG3452@1|root,COG5001@1|root,COG3452@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,42M0W@68525|delta/epsilon subdivisions,2YMHP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	signal transduction protein containing a membrane domain an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,EAL,GGDEF,PAS_4,PAS_9
k141_947_1	1487923.DP73_12425	5.15e-142	426.0	COG0427@1|root,COG0427@2|Bacteria	2|Bacteria	C	acetyl-CoA hydrolase activity	-	-	-	ko:K18122	ko00650,ko01100,ko01200,map00650,map01100,map01200	-	R05336	RC00012,RC00014	ko00000,ko00001,ko01000	-	-	-	AcetylCoA_hyd_C,AcetylCoA_hydro
k141_947_2	272558.10176528	2.73e-47	186.0	COG0840@1|root,COG0840@2|Bacteria,1TP5A@1239|Firmicutes,4H9RZ@91061|Bacilli,1ZBEA@1386|Bacillus	91061|Bacilli	NT	chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal,dCache_1,sCache_3_3
k141_5061_1	667015.Bacsa_2101	6.62e-83	262.0	COG2272@1|root,COG2272@2|Bacteria,4NG5B@976|Bacteroidetes,2FP5J@200643|Bacteroidia,4AKWU@815|Bacteroidaceae	976|Bacteroidetes	I	Belongs to the type-B carboxylesterase lipase family	-	-	-	ko:K03929	-	-	-	-	ko00000,ko01000	-	CE10	-	COesterase
k141_4834_30	445974.CLORAM_01650	4.19e-159	459.0	COG1403@1|root,COG1403@2|Bacteria,1VTXJ@1239|Firmicutes	1239|Firmicutes	L	HNH nucleases	-	-	-	-	-	-	-	-	-	-	-	-	HNH
k141_4834_31	1511.CLOST_2533	4.96e-79	238.0	COG1576@1|root,COG1576@2|Bacteria,1V3JM@1239|Firmicutes,24HED@186801|Clostridia,25RPM@186804|Peptostreptococcaceae	186801|Clostridia	J	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA	rlmH	-	2.1.1.177	ko:K00783	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SPOUT_MTase
k141_4834_33	1033737.CAEV01000110_gene1179	7.36e-171	494.0	COG1757@1|root,COG1757@2|Bacteria,1TQ3B@1239|Firmicutes,248WN@186801|Clostridia,36FFK@31979|Clostridiaceae	186801|Clostridia	C	Na H antiporter	-	-	-	ko:K03315	-	-	-	-	ko00000,ko02000	2.A.35	-	-	Na_H_antiporter
k141_4834_35	926554.KI912675_gene2204	8.07e-09	65.1	COG1835@1|root,COG1835@2|Bacteria	2|Bacteria	I	transferase activity, transferring acyl groups other than amino-acyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
k141_4834_36	1384057.CD33_10965	3.04e-57	200.0	COG0789@1|root,COG0789@2|Bacteria,1V12J@1239|Firmicutes,4HTTQ@91061|Bacilli	91061|Bacilli	K	MerR HTH family regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1,Methyltransf_31
k141_4834_38	96561.Dole_1154	1.81e-10	70.5	COG0666@1|root,COG0666@2|Bacteria,1RBYV@1224|Proteobacteria,42TI1@68525|delta/epsilon subdivisions,2WQ9N@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM Ankyrin	-	-	-	-	-	-	-	-	-	-	-	-	Ank,Ank_2,Ank_3,Ank_4,Ank_5
k141_4834_39	177439.DP2071	4.98e-125	390.0	COG1879@1|root,COG3437@1|root,COG1879@2|Bacteria,COG3437@2|Bacteria,1QUN9@1224|Proteobacteria,42PB6@68525|delta/epsilon subdivisions,2WJJ9@28221|Deltaproteobacteria,2MHWZ@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Domain of unknown function (DUF3369)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3369,HD,HD_5,Response_reg
k141_4834_41	1121324.CLIT_10c04190	1.57e-106	324.0	COG5438@1|root,COG5438@2|Bacteria,1TPEV@1239|Firmicutes,249SW@186801|Clostridia	186801|Clostridia	S	YibE F family protein	-	-	-	-	-	-	-	-	-	-	-	-	YibE_F
k141_4834_42	411490.ANACAC_00836	1.03e-66	210.0	COG0652@1|root,COG0652@2|Bacteria,1TRHW@1239|Firmicutes,247XN@186801|Clostridia	186801|Clostridia	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	ppiB	-	5.2.1.8	ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Pro_isomerase
k141_4834_44	1540257.JQMW01000013_gene1106	7e-169	484.0	COG0520@1|root,COG0520@2|Bacteria,1TQ1W@1239|Firmicutes,249CS@186801|Clostridia,36EP2@31979|Clostridiaceae	186801|Clostridia	E	TIGRFAM cysteine desulfurase family protein	csd	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
k141_1097_1	96561.Dole_2050	8.56e-50	184.0	COG3209@1|root,COG3209@2|Bacteria,1MVV1@1224|Proteobacteria,42Q3J@68525|delta/epsilon subdivisions,2WP5U@28221|Deltaproteobacteria,2MKDQ@213118|Desulfobacterales	28221|Deltaproteobacteria	M	TIGRFAM YD repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	RHS_repeat,YwqJ-deaminase
k141_1450_1	1506994.JNLQ01000002_gene3573	6.37e-79	256.0	COG2183@1|root,COG2183@2|Bacteria,1TPFE@1239|Firmicutes,248P0@186801|Clostridia,4BX1Y@830|Butyrivibrio	186801|Clostridia	K	Tex-like protein N-terminal domain	yhgF	-	-	ko:K06959	-	-	-	-	ko00000	-	-	-	HHH_3,S1,Tex_N,Tex_YqgF
k141_3815_1	1190606.AJYG01000179_gene1494	1.09e-14	75.1	COG1167@1|root,COG1167@2|Bacteria,1MUJE@1224|Proteobacteria,1RXYA@1236|Gammaproteobacteria,1XVSK@135623|Vibrionales	135623|Vibrionales	K	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2,GntR
k141_3815_4	598467.BrE312_0992	4.68e-75	250.0	COG3209@1|root,COG3209@2|Bacteria,1NQ44@1224|Proteobacteria,1SK6W@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	RHS Repeat	-	-	-	-	-	-	-	-	-	-	-	-	RHS,RHS_repeat
k141_3523_1	55601.VANGNB10_cI2108	3.07e-37	137.0	COG0189@1|root,COG0189@2|Bacteria,1MX5X@1224|Proteobacteria,1RNXP@1236|Gammaproteobacteria,1XW57@135623|Vibrionales	135623|Vibrionales	HJ	Ribosomal protein S6 modification	-	-	-	-	-	-	-	-	-	-	-	-	RLAN,RimK
k141_3523_2	55601.VANGNB10_cI2107c	2.77e-197	554.0	COG0454@1|root,COG0456@2|Bacteria,1MVZ2@1224|Proteobacteria,1RSC5@1236|Gammaproteobacteria,1XUZD@135623|Vibrionales	135623|Vibrionales	K	Peptidase_C39 like family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10,DUF3335
k141_3523_3	1122201.AUAZ01000009_gene2875	3.95e-307	880.0	COG2206@1|root,COG3437@1|root,COG2206@2|Bacteria,COG3437@2|Bacteria,1MV37@1224|Proteobacteria,1RM9C@1236|Gammaproteobacteria,465R9@72275|Alteromonadaceae	1236|Gammaproteobacteria	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_3,HD_5,dCache_1
k141_3523_4	1348635.BBJY01000008_gene1728	1.13e-187	527.0	COG1816@1|root,COG1816@2|Bacteria,1MWBV@1224|Proteobacteria,1RNVI@1236|Gammaproteobacteria,1XU77@135623|Vibrionales	135623|Vibrionales	F	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism	-	-	3.5.4.2	ko:K21053	ko00230,ko01100,map00230,map01100	-	R01244	RC00477	ko00000,ko00001,ko01000	-	-	-	A_deaminase
k141_3523_6	672.VV93_v1c23340	1.76e-43	144.0	COG3141@1|root,COG3141@2|Bacteria,1N6RQ@1224|Proteobacteria,1SCDB@1236|Gammaproteobacteria,1XXX8@135623|Vibrionales	135623|Vibrionales	S	protein conserved in bacteria	-	-	-	ko:K09918	-	-	-	-	ko00000	-	-	-	YebG
k141_3523_7	1348635.BBJY01000002_gene3503	4.68e-161	457.0	COG0583@1|root,COG0583@2|Bacteria,1MWVU@1224|Proteobacteria,1RPT8@1236|Gammaproteobacteria,1XTXE@135623|Vibrionales	135623|Vibrionales	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
k141_3523_8	575788.VS_0673	8.69e-85	278.0	COG1330@1|root,COG1330@2|Bacteria,1MWTI@1224|Proteobacteria,1RNT0@1236|Gammaproteobacteria,1XTXU@135623|Vibrionales	135623|Vibrionales	L	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity	recC	-	3.1.11.5	ko:K03583	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_V_gamma
k141_1098_1	305900.GV64_22395	2.22e-65	208.0	COG1272@1|root,COG1272@2|Bacteria,1PGRH@1224|Proteobacteria,1RR4R@1236|Gammaproteobacteria,1XJ9M@135619|Oceanospirillales	135619|Oceanospirillales	S	hemolysin III	-	-	-	ko:K11068	-	-	-	-	ko00000,ko02042	-	-	-	HlyIII
k141_1796_2	1265505.ATUG01000003_gene764	8.8e-21	83.6	2ERBQ@1|root,33IXC@2|Bacteria,1NKKD@1224|Proteobacteria,42XGM@68525|delta/epsilon subdivisions,2WTHR@28221|Deltaproteobacteria,2MMDV@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_1796_3	710687.KI912270_gene4496	3.66e-05	50.4	COG0491@1|root,COG0607@1|root,COG0491@2|Bacteria,COG0607@2|Bacteria,2GN50@201174|Actinobacteria,236XH@1762|Mycobacteriaceae	201174|Actinobacteria	P	PFAM beta-lactamase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B,Rhodanese
k141_4526_2	755731.Clo1100_3325	6.16e-53	185.0	292N3@1|root,2ZQ5Z@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_1100_1	1304885.AUEY01000022_gene3392	2.33e-101	312.0	COG3573@1|root,COG3573@2|Bacteria,1MVX8@1224|Proteobacteria	1224|Proteobacteria	S	Fumarate reductase succinate dehydrogenase flavoprotein	MA20_22130	-	-	ko:K07077	-	-	-	-	ko00000	-	-	-	FAD_binding_2
k141_1451_2	87626.PTD2_01946	5.56e-88	263.0	COG0693@1|root,COG0693@2|Bacteria,1N8N6@1224|Proteobacteria,1S32P@1236|Gammaproteobacteria,2Q2CB@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	S	DJ-1/PfpI family	thiJ	-	4.2.1.103	ko:K18199	ko00930,map00930	-	R05771	RC01467	ko00000,ko00001,ko01000,ko01002	-	-	-	DJ-1_PfpI
k141_1451_3	1118054.CAGW01000083_gene2890	7.04e-06	53.9	COG0834@1|root,COG0834@2|Bacteria,1UXYA@1239|Firmicutes,4H9NJ@91061|Bacilli,26SGB@186822|Paenibacillaceae	91061|Bacilli	ET	ABC transporter substrate-binding protein	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
k141_4528_1	1121456.ATVA01000011_gene1502	5.18e-191	556.0	COG0370@1|root,COG0370@2|Bacteria,1MUZC@1224|Proteobacteria,42MCY@68525|delta/epsilon subdivisions,2WIWJ@28221|Deltaproteobacteria,2M83R@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	transporter of a GTP-driven Fe(2 ) uptake system	feoB	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoB_C,FeoB_N,Gate
k141_4841_1	1219080.VEZ01S_38_00170	1.38e-28	104.0	2AY47@1|root,31Q63@2|Bacteria,1QMUE@1224|Proteobacteria,1TK4S@1236|Gammaproteobacteria,1Y22P@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_4841_2	1348635.BBJY01000002_gene3395	1.61e-38	129.0	2DNTG@1|root,32Z26@2|Bacteria,1N9KE@1224|Proteobacteria,1SFHD@1236|Gammaproteobacteria,1XYK8@135623|Vibrionales	135623|Vibrionales	S	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
k141_4841_3	1348635.BBJY01000002_gene3396	3.22e-48	169.0	2AXZP@1|root,31Q18@2|Bacteria,1QMPU@1224|Proteobacteria,1TJZG@1236|Gammaproteobacteria,1Y1W4@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_3816_1	177439.DP0569	5.7e-32	137.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria	1224|Proteobacteria	NT	Methyl-accepting chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal,dCache_1,dCache_3
k141_3816_2	1278307.KB907014_gene3505	1.56e-55	185.0	COG0834@1|root,COG0834@2|Bacteria,1R4SQ@1224|Proteobacteria,1RQ7A@1236|Gammaproteobacteria	1236|Gammaproteobacteria	ET	ABC-type amino acid transport signal transduction systems periplasmic component domain	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
k141_2432_2	945550.VISI1226_00480	1.66e-91	275.0	COG1346@1|root,COG1346@2|Bacteria,1MV81@1224|Proteobacteria,1RS5C@1236|Gammaproteobacteria,1XT9T@135623|Vibrionales	135623|Vibrionales	M	effector of murein hydrolase	yohK	-	-	-	-	-	-	-	-	-	-	-	LrgB
k141_2432_3	945550.VISI1226_00485	8.05e-88	271.0	COG0295@1|root,COG0295@2|Bacteria,1MY2R@1224|Proteobacteria,1RMRX@1236|Gammaproteobacteria,1XV0Z@135623|Vibrionales	135623|Vibrionales	F	This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis	cdd	GO:0003674,GO:0003824,GO:0004126,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006216,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008655,GO:0009056,GO:0009058,GO:0009116,GO:0009119,GO:0009164,GO:0009972,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042454,GO:0043094,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046087,GO:0046131,GO:0046133,GO:0046135,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:1901135,GO:1901136,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901657,GO:1901658	3.5.4.5	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01878,R02485,R08221	RC00074,RC00514	ko00000,ko00001,ko01000	-	-	-	dCMP_cyt_deam_1,dCMP_cyt_deam_2
k141_2432_4	55601.VANGNB10_cI1542c	1.28e-222	660.0	COG2199@1|root,COG2200@1|root,COG3322@1|root,COG2199@2|Bacteria,COG2200@2|Bacteria,COG3322@2|Bacteria,1NSEP@1224|Proteobacteria,1SMC0@1236|Gammaproteobacteria,1XVRS@135623|Vibrionales	135623|Vibrionales	T	CHASE4 domain	-	-	-	-	-	-	-	-	-	-	-	-	CHASE4,EAL,GGDEF,PAS_9
k141_2432_5	243277.VC_1228	4.09e-207	581.0	COG0027@1|root,COG0027@2|Bacteria,1N3KA@1224|Proteobacteria,1RNTW@1236|Gammaproteobacteria,1XUDQ@135623|Vibrionales	135623|Vibrionales	F	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate	purT	GO:0003674,GO:0003824,GO:0004644,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016742,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.1.2.2	ko:K08289	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp,Epimerase
k141_2432_6	55601.VANGNB10_cI1547c	1.48e-58	181.0	COG0776@1|root,COG0776@2|Bacteria,1RH5Z@1224|Proteobacteria,1S61Z@1236|Gammaproteobacteria,1XXSU@135623|Vibrionales	135623|Vibrionales	K	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control	himA	GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0044424,GO:0044444,GO:0044464,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141	-	ko:K04764	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
k141_3524_1	1484157.PSNIH2_20225	3.21e-286	791.0	COG4584@1|root,COG4584@2|Bacteria,1MU2G@1224|Proteobacteria,1RQA2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	rve
k141_3524_2	595494.Tola_1607	7.98e-123	356.0	COG1484@1|root,COG1484@2|Bacteria,1MVU2@1224|Proteobacteria,1RNUA@1236|Gammaproteobacteria,1Y4PZ@135624|Aeromonadales	135624|Aeromonadales	L	IstB-like ATP binding protein	-	-	-	-	-	-	-	-	-	-	-	-	IstB_IS21,IstB_IS21_ATP
k141_3524_3	243277.VC_1469	2.58e-59	203.0	2CDPS@1|root,2ZBQT@2|Bacteria,1RB59@1224|Proteobacteria,1S2U0@1236|Gammaproteobacteria,1XW3J@135623|Vibrionales	135623|Vibrionales	S	Phage replication protein CRI	-	-	-	-	-	-	-	-	-	-	-	-	Phage_CRI,Phage_X
k141_4842_1	1348635.BBJY01000007_gene141	9e-28	110.0	2AXDX@1|root,31PD9@2|Bacteria,1QM3D@1224|Proteobacteria,1TJAV@1236|Gammaproteobacteria,1Y0X8@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_1101_2	264462.Bd3153	1.49e-39	150.0	COG0574@1|root,COG3848@1|root,COG0574@2|Bacteria,COG3848@2|Bacteria,1MU0R@1224|Proteobacteria,42NYJ@68525|delta/epsilon subdivisions,2MTQT@213481|Bdellovibrionales,2WKYM@28221|Deltaproteobacteria	213481|Bdellovibrionales	GT	Phosphoenolpyruvate synthase	ppsA	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PPDK_N
k141_1452_2	948565.AFFP02000001_gene906	1.41e-33	120.0	COG3150@1|root,COG3150@2|Bacteria,1NV1Y@1224|Proteobacteria,1RPQX@1236|Gammaproteobacteria,1Y89I@135625|Pasteurellales	135625|Pasteurellales	S	Uncharacterised protein family (UPF0227)	-	-	-	ko:K07000	-	-	-	-	ko00000	-	-	-	UPF0227
k141_4529_1	29495.EA26_07265	0.0	922.0	COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria,1MWKS@1224|Proteobacteria,1RMIH@1236|Gammaproteobacteria,1XSJE@135623|Vibrionales	135623|Vibrionales	J	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily	pheT	GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
k141_4843_1	1121396.KB892916_gene77	1.6e-41	141.0	COG0848@1|root,COG0848@2|Bacteria,1RI4M@1224|Proteobacteria,42SKN@68525|delta/epsilon subdivisions,2WNIQ@28221|Deltaproteobacteria,2MPVP@213118|Desulfobacterales	28221|Deltaproteobacteria	U	Biopolymer transport protein ExbD/TolR	-	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
k141_4843_2	572265.HDEF_2066	2.77e-14	77.4	COG0810@1|root,COG0810@2|Bacteria,1MXBE@1224|Proteobacteria,1RMI4@1236|Gammaproteobacteria,282UA@191675|unclassified Enterobacteriaceae	1236|Gammaproteobacteria	U	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	tonB	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0007154,GO:0007165,GO:0008150,GO:0009897,GO:0009986,GO:0009987,GO:0015688,GO:0015833,GO:0015889,GO:0015891,GO:0015893,GO:0016020,GO:0016021,GO:0016032,GO:0019058,GO:0019062,GO:0019904,GO:0022610,GO:0023052,GO:0030288,GO:0030313,GO:0031224,GO:0031226,GO:0031233,GO:0031975,GO:0031992,GO:0032991,GO:0042221,GO:0042493,GO:0042597,GO:0042886,GO:0042891,GO:0042914,GO:0043213,GO:0044403,GO:0044406,GO:0044419,GO:0044425,GO:0044459,GO:0044464,GO:0044650,GO:0046813,GO:0050789,GO:0050794,GO:0050896,GO:0051179,GO:0051180,GO:0051181,GO:0051234,GO:0051704,GO:0051716,GO:0060089,GO:0065007,GO:0071575,GO:0071702,GO:0071705,GO:0071944,GO:0098002,GO:0098552,GO:0098670,GO:0098796,GO:0098797,GO:1901678	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	iAPECO1_1312.APECO1_368,iEC55989_1330.EC55989_1350,iECABU_c1320.ECABU_c15340,iECNA114_1301.ECNA114_1423,iECO103_1326.ECO103_1353,iECP_1309.ECP_1300,iECSF_1327.ECSF_1233,iEcE24377_1341.EcE24377A_1410	TonB_C,TonB_N
k141_1103_1	1232437.KL661988_gene116	4.12e-20	89.4	COG0373@1|root,COG0373@2|Bacteria,1MU41@1224|Proteobacteria,42MUG@68525|delta/epsilon subdivisions,2WISB@28221|Deltaproteobacteria,2MIIU@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,GlutR_dimer,Shikimate_DH
k141_1103_2	398767.Glov_0504	1.31e-38	142.0	COG0755@1|root,COG0755@2|Bacteria,1RCCI@1224|Proteobacteria,42PVM@68525|delta/epsilon subdivisions,2WJ7I@28221|Deltaproteobacteria,43TXA@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	PFAM cytochrome c assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm
k141_2100_1	1007103.AFHW01000174_gene2480	5.06e-19	96.3	COG0845@1|root,COG0845@2|Bacteria,1V2JZ@1239|Firmicutes,4HEMZ@91061|Bacilli,26UMD@186822|Paenibacillaceae	91061|Bacilli	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
k141_2100_2	1121324.CLIT_13c01100	0.0	1370.0	COG0841@1|root,COG0841@2|Bacteria,1TQ03@1239|Firmicutes,2491S@186801|Clostridia,25QT4@186804|Peptostreptococcaceae	186801|Clostridia	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
k141_502_4	1121447.JONL01000001_gene1067	1.48e-56	185.0	COG0476@1|root,COG0476@2|Bacteria,1R87S@1224|Proteobacteria,42R16@68525|delta/epsilon subdivisions,2WNMW@28221|Deltaproteobacteria,2MBEH@213115|Desulfovibrionales	28221|Deltaproteobacteria	H	PFAM UBA THIF-type NAD FAD binding protein	-	-	2.7.7.73	ko:K03148	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07459	RC00043	ko00000,ko00001,ko01000	-	-	-	Prok-JAB,ThiF
k141_502_5	526222.Desal_2649	4.79e-78	244.0	COG0502@1|root,COG0502@2|Bacteria,1MXK0@1224|Proteobacteria,42M3U@68525|delta/epsilon subdivisions,2WJQ6@28221|Deltaproteobacteria,2MG7N@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	TIGRFAM thiazole biosynthesis protein ThiH	thiH	-	4.1.99.19	ko:K03150	ko00730,ko01100,map00730,map01100	-	R10246	RC01434,RC03095	ko00000,ko00001,ko01000	-	-	-	BATS,Radical_SAM
k141_2124_1	866775.HMPREF9243_1516	1.32e-39	145.0	COG0389@1|root,COG0389@2|Bacteria,1TP42@1239|Firmicutes,4HADJ@91061|Bacilli,27DT6@186827|Aerococcaceae	91061|Bacilli	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	dinB	GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
k141_2125_1	243277.VC_0755	3.19e-13	68.6	COG0260@1|root,COG0260@2|Bacteria,1MUIN@1224|Proteobacteria,1RNFI@1236|Gammaproteobacteria,1XUTG@135623|Vibrionales	135623|Vibrionales	E	Probably plays an important role in intracellular peptide degradation	pepB	GO:0003674,GO:0003824,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:0140096,GO:1901564	3.4.11.23	ko:K07751	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	DUF3663,Peptidase_M17
k141_2125_2	243277.VC_0756	7.56e-77	231.0	COG0105@1|root,COG0105@2|Bacteria,1R9ZA@1224|Proteobacteria,1S1Z3@1236|Gammaproteobacteria,1XX25@135623|Vibrionales	135623|Vibrionales	F	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate	ndk	GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564	2.7.4.6	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	M00049,M00050,M00052,M00053	R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895	RC00002	ko00000,ko00001,ko00002,ko01000,ko04131	-	-	-	NDK
k141_503_1	1121447.JONL01000009_gene2555	2.11e-69	244.0	COG2931@1|root,COG3210@1|root,COG4625@1|root,COG2931@2|Bacteria,COG3210@2|Bacteria,COG4625@2|Bacteria,1MU7T@1224|Proteobacteria	1224|Proteobacteria	Q	COG2931, RTX toxins and related Ca2 -binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	HCBP_related,HemolysinCabind
k141_1810_1	879212.DespoDRAFT_03683	9.07e-77	265.0	COG0304@1|root,COG1028@1|root,COG2070@1|root,COG3321@1|root,COG0304@2|Bacteria,COG1028@2|Bacteria,COG2070@2|Bacteria,COG3321@2|Bacteria,1R89Z@1224|Proteobacteria,42NGA@68525|delta/epsilon subdivisions,2WJK3@28221|Deltaproteobacteria,2MIK4@213118|Desulfobacterales	28221|Deltaproteobacteria	IQ	Beta-ketoacyl synthase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_1,KAsynt_C_assoc,KR,Ketoacyl-synt_C,NMO,PP-binding,PS-DH,ketoacyl-synt
k141_4881_1	1121448.DGI_0910	0.000311	48.5	COG1541@1|root,COG1541@2|Bacteria,1MV1W@1224|Proteobacteria,42P78@68525|delta/epsilon subdivisions,2WK1S@28221|Deltaproteobacteria,2MA32@213115|Desulfovibrionales	28221|Deltaproteobacteria	H	PFAM AMP-dependent synthetase	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding
k141_4881_2	1227352.C173_04691	2.61e-90	280.0	COG3172@1|root,COG3172@2|Bacteria,1TQ29@1239|Firmicutes,4HBZT@91061|Bacilli,26SKF@186822|Paenibacillaceae	91061|Bacilli	H	Cytidyltransferase	-	-	2.7.1.22,2.7.7.1	ko:K06211	ko00760,ko01100,map00760,map01100	-	R00137,R02324,R03005	RC00002,RC00017	ko00000,ko00001,ko01000,ko03000	-	-	-	AAA_28,CTP_transf_like
k141_4881_3	1123274.KB899416_gene2635	3.4e-74	231.0	COG3201@1|root,COG3201@2|Bacteria	2|Bacteria	H	nicotinamide mononucleotide transporter	pnuC	GO:0003674,GO:0005215,GO:0005337,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0015858,GO:0015931,GO:0015932,GO:0016020,GO:0022857,GO:0034257,GO:0034258,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:1901264,GO:1901505,GO:1901642	-	ko:K03811	-	-	-	-	ko00000,ko02000	4.B.1.1	-	iSDY_1059.SDY_0695	NMN_transporter
k141_4881_4	941449.dsx2_0052	9.28e-98	295.0	COG3638@1|root,COG3638@2|Bacteria,1MVE9@1224|Proteobacteria,42NZC@68525|delta/epsilon subdivisions,2WN3Y@28221|Deltaproteobacteria,2M9IP@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system	phnC	-	3.6.3.28	ko:K02041	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.9	-	-	ABC_tran
k141_4882_1	998674.ATTE01000001_gene3082	5.67e-71	228.0	COG0714@1|root,COG0714@2|Bacteria,1RJBX@1224|Proteobacteria,1S87A@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	ATPase, AAA	-	-	-	-	-	-	-	-	-	-	-	-	AAA_5
k141_504_1	177437.HRM2_17880	8.19e-40	137.0	COG1607@1|root,COG1607@2|Bacteria,1RAEQ@1224|Proteobacteria,42SPA@68525|delta/epsilon subdivisions,2WPPE@28221|Deltaproteobacteria,2MJW0@213118|Desulfobacterales	28221|Deltaproteobacteria	I	Thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
k141_2126_1	672.VV93_v1c43960	6.79e-40	154.0	COG3209@1|root,COG3209@2|Bacteria,1PDT2@1224|Proteobacteria,1TEF8@1236|Gammaproteobacteria,1XZDG@135623|Vibrionales	135623|Vibrionales	M	COG3209 Rhs family protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_4547_1	1348635.BBJY01000016_gene4016	2.85e-36	124.0	COG0640@1|root,COG0640@2|Bacteria,1MZT1@1224|Proteobacteria,1SAI5@1236|Gammaproteobacteria,1XXDF@135623|Vibrionales	135623|Vibrionales	K	transcriptional	arsR	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5
k141_4547_2	243277.VC_0137	1.06e-171	494.0	COG3434@1|root,COG3434@2|Bacteria,1MVW1@1224|Proteobacteria,1RS25@1236|Gammaproteobacteria,1XTJ5@135623|Vibrionales	135623|Vibrionales	T	signal transduction protein containing EAL and modified HD-GYP domains	-	-	3.1.4.52	ko:K07181	ko05111,map05111	-	-	-	ko00000,ko00001,ko01000	-	-	-	EAL,HDOD
k141_4547_3	1517681.HW45_27640	4.66e-106	320.0	COG2267@1|root,COG2267@2|Bacteria,1MWDA@1224|Proteobacteria,1RRJP@1236|Gammaproteobacteria,1XTME@135623|Vibrionales	135623|Vibrionales	I	Lysophospholipase	pldB	-	3.1.1.5	ko:K01048	ko00564,map00564	-	-	-	ko00000,ko00001,ko01000	-	-	-	Hydrolase_4
k141_4547_4	243277.VC_0134	1.66e-124	362.0	COG0561@1|root,COG0561@2|Bacteria,1MV02@1224|Proteobacteria,1RP1D@1236|Gammaproteobacteria,1XTVR@135623|Vibrionales	135623|Vibrionales	S	hydrolases of the HAD superfamily	yigL	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
k141_2841_43	1304284.L21TH_1661	9.44e-57	183.0	298ZI@1|root,2ZW3A@2|Bacteria,1V7FU@1239|Firmicutes,24ID8@186801|Clostridia,36KW8@31979|Clostridiaceae	186801|Clostridia	S	ECF transporter, substrate-specific component	-	-	-	ko:K16788	-	-	-	-	ko00000,ko02000	2.A.88.5	-	-	ECF_trnsprt
k141_2841_44	1121324.CLIT_10c03150	1.07e-18	92.8	COG5513@1|root,COG5513@2|Bacteria,1V52X@1239|Firmicutes,25ER6@186801|Clostridia	186801|Clostridia	S	Protein of unknown function (DUF3298)	-	-	-	-	-	-	-	-	-	-	-	-	Cu_amine_oxidN1,DUF3298,DUF4163
k141_2841_45	358681.BBR47_12970	3.32e-38	138.0	2BM45@1|root,32FMH@2|Bacteria,1V9CH@1239|Firmicutes,4HIZX@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_2841_46	1121289.JHVL01000049_gene864	1.45e-94	282.0	COG0745@1|root,COG0745@2|Bacteria,1TT73@1239|Firmicutes,2487E@186801|Clostridia,36EGW@31979|Clostridiaceae	186801|Clostridia	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
k141_2841_47	536227.CcarbDRAFT_4787	1.89e-116	357.0	COG0642@1|root,COG2205@2|Bacteria,1TRD2@1239|Firmicutes,247M3@186801|Clostridia,36EWQ@31979|Clostridiaceae	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
k141_2841_49	632518.Calow_2008	1.36e-11	76.6	COG0840@1|root,COG0840@2|Bacteria,1TP5A@1239|Firmicutes,247S3@186801|Clostridia,42FW1@68295|Thermoanaerobacterales	186801|Clostridia	NT	histidine kinase HAMP region domain protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal,dCache_1
k141_2841_50	1215915.BN193_02940	8.99e-24	107.0	COG4129@1|root,COG4129@2|Bacteria,1TP2T@1239|Firmicutes,4HAWV@91061|Bacilli,1YCDX@1357|Lactococcus	91061|Bacilli	S	Putative aromatic acid exporter C-terminal domain	yqjA	-	-	-	-	-	-	-	-	-	-	-	ArAE_1,ArAE_1_C
k141_2841_51	1391647.AVSV01000036_gene882	2.85e-191	541.0	COG1979@1|root,COG1979@2|Bacteria,1TPS3@1239|Firmicutes,248DW@186801|Clostridia,36EU1@31979|Clostridiaceae	186801|Clostridia	C	Dehydrogenase	yqhD	-	-	ko:K08325,ko:K19955	ko00640,map00640	-	R02528	RC00739	ko00000,ko00001,ko01000	-	-	-	Fe-ADH
k141_2841_52	335541.Swol_0927	1.27e-46	179.0	COG0840@1|root,COG3290@1|root,COG0840@2|Bacteria,COG3290@2|Bacteria,1TP5A@1239|Firmicutes,247S3@186801|Clostridia,42KHD@68298|Syntrophomonadaceae	186801|Clostridia	NT	chemotaxis sensory transducer	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,CHASE3,HAMP,MCPsignal,dCache_1,sCache_3_3
k141_2841_53	386415.NT01CX_0309	7.7e-115	350.0	COG1115@1|root,COG1115@2|Bacteria,1VSJ9@1239|Firmicutes,24EMY@186801|Clostridia,36I60@31979|Clostridiaceae	186801|Clostridia	E	amino acid carrier protein	-	-	-	-	-	-	-	-	-	-	-	-	Na_Ala_symp
k141_2841_54	318464.IO99_08150	2.44e-63	203.0	COG2391@1|root,COG2391@2|Bacteria,1TS7S@1239|Firmicutes,24CIP@186801|Clostridia,36I97@31979|Clostridiaceae	186801|Clostridia	S	Sulphur transport	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
k141_2841_55	1304284.L21TH_2394	6.47e-20	82.4	COG0425@1|root,COG0425@2|Bacteria,1VDPY@1239|Firmicutes,24NT3@186801|Clostridia,36M28@31979|Clostridiaceae	186801|Clostridia	O	Belongs to the sulfur carrier protein TusA family	-	-	-	-	-	-	-	-	-	-	-	-	TusA
k141_2841_56	318464.IO99_08140	6.32e-81	244.0	COG2391@1|root,COG2391@2|Bacteria,1V9KG@1239|Firmicutes,25DZD@186801|Clostridia,36I84@31979|Clostridiaceae	186801|Clostridia	S	YeeE YedE family protein	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
k141_3250_1	1265505.ATUG01000002_gene2092	6.19e-71	220.0	COG3897@1|root,COG3897@2|Bacteria,1MUWA@1224|Proteobacteria,42NV1@68525|delta/epsilon subdivisions,2WJZ9@28221|Deltaproteobacteria,2MID4@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Lysine methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_16,PrmA
k141_3250_2	1307759.JOMJ01000004_gene3046	1.48e-292	812.0	COG1653@1|root,COG1653@2|Bacteria,1MV8A@1224|Proteobacteria,42N6A@68525|delta/epsilon subdivisions,2WIPX@28221|Deltaproteobacteria,2MFYF@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	ABC-type sugar transport system periplasmic component	-	-	-	ko:K17321	ko02010,map02010	M00607	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.35	-	-	-
k141_3658_2	693444.D782_1271	6.07e-37	131.0	COG0700@1|root,COG0700@2|Bacteria,1R4W8@1224|Proteobacteria,1T006@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Nucleoside recognition	yjiG	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Gate
k141_3658_3	1517681.HW45_11730	1.15e-55	184.0	COG3366@1|root,COG3366@2|Bacteria,1NP3U@1224|Proteobacteria,1RNFQ@1236|Gammaproteobacteria,1XSKS@135623|Vibrionales	135623|Vibrionales	S	Nucleoside recognition	yjiH	-	-	-	-	-	-	-	-	-	-	-	Gate
k141_336_1	1121396.KB893068_gene1415	2.55e-71	224.0	2DIIP@1|root,303E3@2|Bacteria,1QQI7@1224|Proteobacteria,435JC@68525|delta/epsilon subdivisions,2WZXF@28221|Deltaproteobacteria,2MNJI@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_1281_1	672.VV93_v1c30600	4.85e-147	435.0	COG1523@1|root,COG1523@2|Bacteria,1MU19@1224|Proteobacteria,1RP6F@1236|Gammaproteobacteria,1XTF4@135623|Vibrionales	135623|Vibrionales	G	Belongs to the glycosyl hydrolase 13 family	glgX	-	3.2.1.68	ko:K01214	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R09995,R11261	-	ko00000,ko00001,ko00002,ko01000	-	CBM48,GH13	-	Alpha-amylase,CBM_48
k141_1281_2	617140.AJZE01000090_gene4299	0.0	903.0	COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,1RMUR@1236|Gammaproteobacteria,1XSH6@135623|Vibrionales	135623|Vibrionales	V	COG1132 ABC-type multidrug transport system, ATPase and permease components	vcaM	-	-	ko:K18893	ko02010,map02010	-	-	-	ko00000,ko00001,ko02000	3.A.1	-	-	ABC_membrane,ABC_tran
k141_1281_3	29495.EA26_08710	4.31e-83	254.0	COG2733@1|root,COG2733@2|Bacteria,1R4JT@1224|Proteobacteria,1RRVB@1236|Gammaproteobacteria,1XU14@135623|Vibrionales	135623|Vibrionales	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF445
k141_609_2	1232410.KI421413_gene853	6.98e-111	328.0	COG0668@1|root,COG0668@2|Bacteria,1N596@1224|Proteobacteria,42PH4@68525|delta/epsilon subdivisions,2WME5@28221|Deltaproteobacteria,43T1N@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Conserved TM helix	-	-	-	ko:K03442	-	-	-	-	ko00000,ko02000	1.A.23.2	-	-	MS_channel,TM_helix
k141_1962_1	82996.sch_12395	1.17e-24	100.0	COG0667@1|root,COG0667@2|Bacteria,1MV2Y@1224|Proteobacteria,1RPIE@1236|Gammaproteobacteria,4030R@613|Serratia	1236|Gammaproteobacteria	C	aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
k141_1962_2	1348635.BBJY01000038_gene9	1.88e-59	185.0	COG0789@1|root,COG0789@2|Bacteria,1N9C6@1224|Proteobacteria,1SAI3@1236|Gammaproteobacteria,1XXVP@135623|Vibrionales	135623|Vibrionales	K	helix_turn_helix, mercury resistance	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
k141_1962_4	715451.ambt_17240	5.42e-36	131.0	COG0406@1|root,COG0406@2|Bacteria,1N0M0@1224|Proteobacteria,1SCAZ@1236|Gammaproteobacteria,46AW5@72275|Alteromonadaceae	1236|Gammaproteobacteria	G	phosphoglycerate mutase	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
k141_1962_5	1238450.VIBNISOn1_30024	1.51e-80	242.0	COG1683@1|root,COG1683@2|Bacteria,1RHER@1224|Proteobacteria,1S6AV@1236|Gammaproteobacteria,1XX92@135623|Vibrionales	135623|Vibrionales	S	Protein of unknown function (DUF523)	-	-	-	-	-	-	-	-	-	-	-	-	DUF523
k141_1962_6	998674.ATTE01000001_gene3842	1.11e-72	233.0	COG3177@1|root,COG3177@2|Bacteria,1MV69@1224|Proteobacteria,1RM9J@1236|Gammaproteobacteria,4621I@72273|Thiotrichales	72273|Thiotrichales	S	Fic/DOC family	-	-	-	-	-	-	-	-	-	-	-	-	Fic
k141_860_1	1173020.Cha6605_1068	3.99e-76	241.0	COG4886@1|root,COG4886@2|Bacteria,1GD11@1117|Cyanobacteria	1117|Cyanobacteria	S	Wd-40 repeat	-	-	-	-	-	-	-	-	-	-	-	-	LRR_6
k141_338_1	485915.Dret_0347	2.89e-31	119.0	COG4977@1|root,COG4977@2|Bacteria,1MUDK@1224|Proteobacteria,42QRG@68525|delta/epsilon subdivisions,2WJ5Z@28221|Deltaproteobacteria,2MBCF@213115|Desulfovibrionales	28221|Deltaproteobacteria	K	PFAM helix-turn-helix- domain containing protein AraC type	-	-	-	-	-	-	-	-	-	-	-	-	DJ-1_PfpI,HTH_18
k141_610_1	269482.Bcep1808_7642	4.27e-12	68.9	28YN0@1|root,2ZKFN@2|Bacteria,1PB4Q@1224|Proteobacteria,2W667@28216|Betaproteobacteria,1KAG7@119060|Burkholderiaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_610_2	675813.VIB_000195	1.21e-19	82.8	2AXT7@1|root,31PU6@2|Bacteria,1QMH5@1224|Proteobacteria,1TJSH@1236|Gammaproteobacteria,1Y1MF@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_2536_1	1219065.VPR01S_13_01280	8.52e-11	61.6	COG0843@1|root,COG0843@2|Bacteria,1MU7S@1224|Proteobacteria,1RPC3@1236|Gammaproteobacteria,1XU9F@135623|Vibrionales	135623|Vibrionales	C	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B	cyoB	-	1.10.3.10	ko:K02298	ko00190,ko01100,map00190,map01100	M00417	R11335	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.5	-	-	COX1
k141_2536_2	316275.VSAL_II0163	5.61e-124	364.0	COG1622@1|root,COG1622@2|Bacteria,1MWHZ@1224|Proteobacteria,1RP4H@1236|Gammaproteobacteria,1XUJG@135623|Vibrionales	135623|Vibrionales	C	subunit 2	cyoA	-	1.10.3.10	ko:K02297	ko00190,ko01100,map00190,map01100	M00417	R11335	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.5	-	-	COX2,COX_ARM
k141_2536_3	675815.VOA_001143	1.24e-148	421.0	COG0217@1|root,COG0217@2|Bacteria,1MW3X@1224|Proteobacteria,1RP5N@1236|Gammaproteobacteria,1XTXW@135623|Vibrionales	135623|Vibrionales	K	transcriptional regulatory protein	yeeN	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
k141_2536_4	675815.VOA_001142	2.51e-19	80.5	2C4PK@1|root,3333R@2|Bacteria,1N7VC@1224|Proteobacteria,1SCZA@1236|Gammaproteobacteria,1XYWF@135623|Vibrionales	135623|Vibrionales	S	Protein of unknown function (DUF3283)	VVA0009	-	-	-	-	-	-	-	-	-	-	-	DUF3283
k141_2536_6	55601.VANGNB10_cII0003	1.56e-24	94.7	2AWN9@1|root,31NJ0@2|Bacteria,1QK9N@1224|Proteobacteria,1TID5@1236|Gammaproteobacteria,1XYWS@135623|Vibrionales	135623|Vibrionales	-	-	VVA0005	-	-	-	-	-	-	-	-	-	-	-	-
k141_3659_1	55601.VANGNB10_cI1061c	2.06e-68	213.0	COG2915@1|root,COG2915@2|Bacteria,1RI8B@1224|Proteobacteria,1RPCC@1236|Gammaproteobacteria,1XT1A@135623|Vibrionales	135623|Vibrionales	S	High frequency lysogenization protein HflD homolog	hflD	-	-	ko:K07153	-	-	-	-	ko00000	-	-	-	DUF489
k141_4665_1	1195246.AGRI_01430	2.14e-68	236.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,464X3@72275|Alteromonadaceae	1236|Gammaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran,DUF805
k141_1282_1	933262.AXAM01000001_gene326	1.12e-287	813.0	COG0060@1|root,COG0060@2|Bacteria,1MVBQ@1224|Proteobacteria,42MKB@68525|delta/epsilon subdivisions,2WJ4W@28221|Deltaproteobacteria,2MI4Z@213118|Desulfobacterales	28221|Deltaproteobacteria	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1,zf-FPG_IleRS
k141_2854_1	96561.Dole_3218	2.64e-170	491.0	COG0569@1|root,COG0569@2|Bacteria,1MW8R@1224|Proteobacteria,42NWZ@68525|delta/epsilon subdivisions,2WJU7@28221|Deltaproteobacteria,2MJ2C@213118|Desulfobacterales	28221|Deltaproteobacteria	P	PFAM TrkA-N domain	trkA	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
k141_2854_2	177437.HRM2_36660	2.53e-213	604.0	COG0168@1|root,COG0168@2|Bacteria,1MUIJ@1224|Proteobacteria,42MPV@68525|delta/epsilon subdivisions,2WJBH@28221|Deltaproteobacteria,2MJ0H@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA	trkH	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
k141_2854_3	56780.SYN_00133	1.56e-34	134.0	COG1560@1|root,COG1560@2|Bacteria,1MVNI@1224|Proteobacteria,42N6U@68525|delta/epsilon subdivisions,2WQ3X@28221|Deltaproteobacteria,2MQIP@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	Bacterial lipid A biosynthesis acyltransferase	htrB	-	2.3.1.241	ko:K02517	ko00540,ko01100,map00540,map01100	M00060	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Lip_A_acyltrans
k141_2854_4	1304885.AUEY01000004_gene953	4.93e-104	309.0	COG0084@1|root,COG0084@2|Bacteria,1MUC0@1224|Proteobacteria,42MMS@68525|delta/epsilon subdivisions,2WMUI@28221|Deltaproteobacteria,2MIBY@213118|Desulfobacterales	28221|Deltaproteobacteria	L	TIGRFAM hydrolase, TatD family	tatD	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	Fer4_14,Radical_SAM,TatD_DNase
k141_2854_5	96561.Dole_0316	1.51e-115	340.0	COG0543@1|root,COG0543@2|Bacteria,1NTWI@1224|Proteobacteria,42M66@68525|delta/epsilon subdivisions,2WJJ2@28221|Deltaproteobacteria,2MI36@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM oxidoreductase FAD NAD(P)-binding domain protein	nfnB	-	1.18.1.2,1.19.1.1	ko:K00528	-	-	R10159	-	ko00000,ko01000	-	-	-	DHODB_Fe-S_bind,NAD_binding_1
k141_2854_6	1304885.AUEY01000004_gene951	1.44e-216	612.0	COG0493@1|root,COG0493@2|Bacteria,1MU2H@1224|Proteobacteria,42MGY@68525|delta/epsilon subdivisions,2WJHC@28221|Deltaproteobacteria,2MHYJ@213118|Desulfobacterales	28221|Deltaproteobacteria	E	TIGRFAM glutamate synthase (NADPH), homotetrameric	-	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	Fer4_20,Pyr_redox_2
k141_611_1	177437.HRM2_11490	1.91e-18	86.7	COG0793@1|root,COG0793@2|Bacteria,1MU39@1224|Proteobacteria,42MHD@68525|delta/epsilon subdivisions,2WJKC@28221|Deltaproteobacteria,2MJ79@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Belongs to the peptidase S41A family	ctpA	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_S41
k141_4292_1	644282.Deba_1682	5.52e-196	576.0	COG1629@1|root,COG4771@2|Bacteria,1MWKN@1224|Proteobacteria,42MNM@68525|delta/epsilon subdivisions,2WK8K@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	TonB-dependent Receptor Plug	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
k141_1965_2	1328313.DS2_15814	2.3e-226	628.0	COG3177@1|root,COG3177@2|Bacteria,1MV69@1224|Proteobacteria,1RM9J@1236|Gammaproteobacteria,465WF@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Filamentation induced by cAMP protein fic	-	-	-	-	-	-	-	-	-	-	-	-	DUF4172,Fic
k141_1965_3	1116375.VEJY3_21616	8.25e-20	86.3	COG0224@1|root,COG0224@2|Bacteria,1RIE5@1224|Proteobacteria,1S3ZW@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	ATP synthase gamma subunit	-	-	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
k141_4293_1	384765.SIAM614_30681	6.16e-27	117.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,2TQR7@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	methyl-accepting chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal,PAS_3,PAS_9
k141_1966_1	672.VV93_v1c22130	2.5e-78	236.0	COG1225@1|root,COG1225@2|Bacteria,1RD4R@1224|Proteobacteria,1RQ7F@1236|Gammaproteobacteria,1XSCX@135623|Vibrionales	135623|Vibrionales	O	COG1225 Peroxiredoxin	-	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
k141_2855_1	349521.HCH_03884	1.87e-36	140.0	COG3409@1|root,COG3409@2|Bacteria,1N63I@1224|Proteobacteria	1224|Proteobacteria	M	Papain-like cysteine protease AvrRpt2	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C70
k141_861_1	1348635.BBJY01000004_gene3055	2e-121	357.0	COG0697@1|root,COG0697@2|Bacteria,1NS7A@1224|Proteobacteria,1S24Q@1236|Gammaproteobacteria,1XVG0@135623|Vibrionales	135623|Vibrionales	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
k141_861_2	998674.ATTE01000001_gene572	4.05e-10	58.5	COG3492@1|root,COG3492@2|Bacteria,1MZ3I@1224|Proteobacteria,1S8SI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	protein conserved in bacteria	IV02_17390	-	-	ko:K09948	-	-	-	-	ko00000	-	-	-	DUF1244
k141_861_3	1219065.VPR01S_03_01180	5.68e-80	240.0	COG1522@1|root,COG1522@2|Bacteria,1RDB3@1224|Proteobacteria,1S2E1@1236|Gammaproteobacteria,1XWVX@135623|Vibrionales	135623|Vibrionales	K	Transcriptional regulator AsnC family	ybaO	-	-	ko:K05800	-	-	-	-	ko00000,ko03000	-	-	-	AsnC_trans_reg,HTH_24,HTH_AsnC-type
k141_861_4	55601.VANGNB10_cI1798	1.14e-165	468.0	COG1946@1|root,COG1946@2|Bacteria,1MV9R@1224|Proteobacteria,1RPFI@1236|Gammaproteobacteria,1XU39@135623|Vibrionales	135623|Vibrionales	I	Acyl-CoA thioesterase	tesB	-	-	ko:K10805	ko01040,map01040	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	4HBT_3
k141_1967_1	234267.Acid_6124	4.77e-67	211.0	COG4974@1|root,COG4974@2|Bacteria	2|Bacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS66,PRiA4_ORF3
k141_3251_2	323850.Shew_1014	9.41e-14	72.0	COG1813@1|root,COG1813@2|Bacteria,1QZ14@1224|Proteobacteria,1T3ZF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	helix-turn-helix domain protein	-	-	-	-	-	-	-	-	-	-	-	-	2TM,HTH_3
k141_3251_4	1348635.BBJY01000015_gene658	1.25e-150	432.0	COG0582@1|root,COG0582@2|Bacteria,1QUFZ@1224|Proteobacteria,1T1XN@1236|Gammaproteobacteria,1XUVH@135623|Vibrionales	135623|Vibrionales	L	Belongs to the 'phage' integrase family	intIA	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
k141_1283_1	1051646.VITU9109_00977	2.77e-87	269.0	COG0349@1|root,COG0349@2|Bacteria,1MURV@1224|Proteobacteria,1RPBP@1236|Gammaproteobacteria,1XSSU@135623|Vibrionales	135623|Vibrionales	J	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides	rnd	-	3.1.13.5	ko:K03684	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DNA_pol_A_exo1,HRDC
k141_1283_2	243277.VC_1985	1.53e-284	789.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,1RMQ4@1236|Gammaproteobacteria,1XVCW@135623|Vibrionales	135623|Vibrionales	IQ	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II	fadD	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
k141_862_1	1304885.AUEY01000008_gene2109	1.67e-76	233.0	COG0066@1|root,COG0066@2|Bacteria,1MVXB@1224|Proteobacteria,42RR2@68525|delta/epsilon subdivisions,2WNPQ@28221|Deltaproteobacteria,2MJTA@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Belongs to the LeuD family	leuD	-	4.2.1.33,4.2.1.35	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R10170	RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1269	Aconitase_C
k141_2856_1	1121396.KB892926_gene3653	1.97e-51	174.0	COG0304@1|root,COG0304@2|Bacteria,1MU1X@1224|Proteobacteria,42PFM@68525|delta/epsilon subdivisions,2WJVK@28221|Deltaproteobacteria,2MJ4Y@213118|Desulfobacterales	28221|Deltaproteobacteria	IQ	Belongs to the beta-ketoacyl-ACP synthases family	-	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
k141_2856_2	1121396.KB892926_gene3652	6.87e-44	143.0	COG0236@1|root,COG0236@2|Bacteria,1PBR6@1224|Proteobacteria,43361@68525|delta/epsilon subdivisions,2WY5N@28221|Deltaproteobacteria,2MP4R@213118|Desulfobacterales	28221|Deltaproteobacteria	IQ	Phosphopantetheine attachment site	-	-	-	-	-	-	-	-	-	-	-	-	PP-binding
k141_2856_3	1121396.KB893128_gene4413	4.46e-30	114.0	COG4261@1|root,COG4261@2|Bacteria,1MVXJ@1224|Proteobacteria,42PI2@68525|delta/epsilon subdivisions,2WMFI@28221|Deltaproteobacteria,2MKJC@213118|Desulfobacterales	28221|Deltaproteobacteria	S	lipid A biosynthesis acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Lip_A_acyltrans
k141_612_1	879212.DespoDRAFT_00562	6.8e-78	265.0	COG2202@1|root,COG2203@1|root,COG4191@1|root,COG4936@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG4191@2|Bacteria,COG4936@2|Bacteria,1R609@1224|Proteobacteria,42MTJ@68525|delta/epsilon subdivisions,2WJYM@28221|Deltaproteobacteria,2MMSJ@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GAF,GAF_2,HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Pkinase
k141_612_2	933262.AXAM01000059_gene2913	4.47e-39	148.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MC4@68525|delta/epsilon subdivisions,2WIZU@28221|Deltaproteobacteria,2MI2B@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_4,PAS_9,Response_reg
k141_1968_1	1265505.ATUG01000001_gene3729	5.67e-95	300.0	COG5009@1|root,COG5009@2|Bacteria,1MU5A@1224|Proteobacteria,42MJB@68525|delta/epsilon subdivisions,2WIXF@28221|Deltaproteobacteria,2MPQ1@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Transglycosylase	mrcA	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	iAF987.Gmet_0354	PCB_OB,Transgly,Transpeptidase
k141_4294_1	1304885.AUEY01000009_gene1926	7.95e-286	799.0	COG0480@1|root,COG0480@2|Bacteria,1MUCV@1224|Proteobacteria,42NDG@68525|delta/epsilon subdivisions,2WKYU@28221|Deltaproteobacteria,2MISU@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA1	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
k141_2538_1	675806.VII_000142	1.59e-155	457.0	COG0564@1|root,COG0564@2|Bacteria,1MVJ5@1224|Proteobacteria,1RN61@1236|Gammaproteobacteria,1XSMM@135623|Vibrionales	135623|Vibrionales	J	COG0564 Pseudouridylate synthases, 23S RNA-specific	-	-	5.4.99.28,5.4.99.29	ko:K06177	-	-	-	-	ko00000,ko01000,ko03009,ko03016	-	-	-	PseudoU_synth_2
k141_2538_2	1208321.D104_17595	1.22e-138	402.0	COG2113@1|root,COG2113@2|Bacteria,1MVIG@1224|Proteobacteria,1RRNK@1236|Gammaproteobacteria,1XNN4@135619|Oceanospirillales	135619|Oceanospirillales	E	Substrate binding domain of ABC-type glycine betaine transport system	-	-	-	ko:K02002	ko02010,map02010	M00208	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	OpuAC
k141_2538_3	1116375.VEJY3_18166	1.25e-71	221.0	COG2135@1|root,COG2135@2|Bacteria,1RER4@1224|Proteobacteria,1RSBH@1236|Gammaproteobacteria,1XXM4@135623|Vibrionales	135623|Vibrionales	S	Belongs to the SOS response-associated peptidase family	-	-	-	-	-	-	-	-	-	-	-	-	SRAP
k141_3956_1	1304885.AUEY01000003_gene545	2.13e-295	845.0	COG0532@1|root,COG0532@2|Bacteria,1MV26@1224|Proteobacteria,42M5Q@68525|delta/epsilon subdivisions,2WIIX@28221|Deltaproteobacteria,2MIGT@213118|Desulfobacterales	28221|Deltaproteobacteria	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,IF-2,IF2_N
k141_3956_2	305900.GV64_22830	3.15e-18	81.6	COG0858@1|root,COG0858@2|Bacteria,1MZPE@1224|Proteobacteria,1S9AF@1236|Gammaproteobacteria,1XKKG@135619|Oceanospirillales	135619|Oceanospirillales	J	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA	rbfA	-	-	ko:K02834	-	-	-	-	ko00000,ko03009	-	-	-	RBFA
k141_3956_3	645991.Sgly_2249	1.11e-61	206.0	COG0618@1|root,COG0618@2|Bacteria,1TPXX@1239|Firmicutes,248R3@186801|Clostridia,261DN@186807|Peptococcaceae	186801|Clostridia	S	DHHA1 domain	nrnA	-	3.1.13.3,3.1.3.7	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
k141_3956_4	1121405.dsmv_2736	3.58e-67	219.0	COG0130@1|root,COG0130@2|Bacteria,1MV0N@1224|Proteobacteria,42MU5@68525|delta/epsilon subdivisions,2WKWY@28221|Deltaproteobacteria,2MJFR@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481	5.4.99.25	ko:K03177	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruB_C,TruB_C_2,TruB_N
k141_3956_5	1120949.KB903356_gene8569	2.14e-34	120.0	COG0184@1|root,COG0184@2|Bacteria,2IQA0@201174|Actinobacteria,4DEJG@85008|Micromonosporales	201174|Actinobacteria	J	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome	rpsO	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0015935,GO:0016020,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
k141_3956_6	1121405.dsmv_2738	2.99e-312	874.0	COG1185@1|root,COG1185@2|Bacteria,1MVB9@1224|Proteobacteria,42MTZ@68525|delta/epsilon subdivisions,2WJCE@28221|Deltaproteobacteria,2MIS9@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004654,GO:0005488,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
k141_3956_7	439235.Dalk_4744	4.47e-108	333.0	COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,42P7N@68525|delta/epsilon subdivisions,2WJKE@28221|Deltaproteobacteria,2MICX@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Insulinase (Peptidase family M16)	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
k141_3956_8	439235.Dalk_4745	4.28e-53	172.0	COG0756@1|root,COG0756@2|Bacteria,1RA7P@1224|Proteobacteria,42SJS@68525|delta/epsilon subdivisions,2WP7N@28221|Deltaproteobacteria,2MK9P@213118|Desulfobacterales	28221|Deltaproteobacteria	F	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA	dut	GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576	3.6.1.23	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	M00053	R02100,R11896	RC00002	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	dUTPase
k141_3956_9	1121405.dsmv_1859	4.08e-89	272.0	COG1235@1|root,COG1235@2|Bacteria,1R5N4@1224|Proteobacteria,42NE6@68525|delta/epsilon subdivisions,2WJ92@28221|Deltaproteobacteria,2MJ1B@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B,Lactamase_B_2
k141_3956_10	1121459.AQXE01000003_gene1149	8.97e-60	200.0	COG1760@1|root,COG1760@2|Bacteria,1MUZN@1224|Proteobacteria,42N88@68525|delta/epsilon subdivisions,2WISX@28221|Deltaproteobacteria,2M8PI@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	PFAM serine dehydratase alpha chain	-	-	4.3.1.17	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	-	R00220,R00590	RC00331,RC02600	ko00000,ko00001,ko01000	-	-	-	SDH_alpha,SDH_beta
k141_1969_1	1167006.UWK_03060	3.2e-62	197.0	COG1014@1|root,COG1014@2|Bacteria,1RBZA@1224|Proteobacteria,42QT3@68525|delta/epsilon subdivisions,2X6H9@28221|Deltaproteobacteria,2MJ4W@213118|Desulfobacterales	28221|Deltaproteobacteria	C	indolepyruvate ferredoxin oxidoreductase, beta subunit	-	-	1.2.7.8	ko:K00180	-	-	-	-	br01601,ko00000,ko01000	-	-	-	POR
k141_4666_1	55601.VANGNB10_cI2329c	5.04e-73	219.0	COG0099@1|root,COG0099@2|Bacteria,1RD1G@1224|Proteobacteria,1S3NX@1236|Gammaproteobacteria,1XXE1@135623|Vibrionales	135623|Vibrionales	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	rpsM	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
k141_4666_2	314292.VAS14_19316	4.26e-18	75.1	COG0257@1|root,COG0257@2|Bacteria,1NGEI@1224|Proteobacteria,1SGC9@1236|Gammaproteobacteria,1XZE6@135623|Vibrionales	135623|Vibrionales	J	Belongs to the bacterial ribosomal protein bL36 family	rpmJ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02919	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L36
k141_4666_3	1219065.VPR01S_04_00810	7.24e-274	754.0	COG0201@1|root,COG0201@2|Bacteria,1MVU7@1224|Proteobacteria,1RNJV@1236|Gammaproteobacteria,1XTJ7@135623|Vibrionales	135623|Vibrionales	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
k141_4666_4	1219065.VPR01S_04_00820	1.08e-84	251.0	COG0200@1|root,COG0200@2|Bacteria,1RDC8@1224|Proteobacteria,1S3P6@1236|Gammaproteobacteria,1XWV4@135623|Vibrionales	135623|Vibrionales	J	Binds to the 23S rRNA	rplO	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02876	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27A
k141_1747_3	1238450.VIBNISOn1_1610066	7.64e-20	80.1	COG0257@1|root,COG0257@2|Bacteria,1NGBJ@1224|Proteobacteria,1SCR7@1236|Gammaproteobacteria,1XZ00@135623|Vibrionales	135623|Vibrionales	J	Belongs to the bacterial ribosomal protein bL36 family	rpmJ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02919	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L36
k141_1747_4	945543.VIBR0546_12897	1.47e-128	385.0	COG4097@1|root,COG4097@2|Bacteria,1MV9P@1224|Proteobacteria,1RR7V@1236|Gammaproteobacteria,1XUW4@135623|Vibrionales	135623|Vibrionales	P	FAD-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_8,Ferric_reduct,NAD_binding_1
k141_1747_5	55601.VANGNB10_cII0572c	4.91e-49	165.0	COG4067@1|root,COG4067@2|Bacteria,1N7Y2@1224|Proteobacteria,1SBQN@1236|Gammaproteobacteria,1XUTD@135623|Vibrionales	135623|Vibrionales	O	protein conserved in archaea	-	-	-	-	-	-	-	-	-	-	-	-	Zn_protease
k141_1747_6	481805.EcolC_3774	1.07e-58	184.0	COG0602@1|root,COG0602@2|Bacteria,1RA7S@1224|Proteobacteria,1S20X@1236|Gammaproteobacteria,3XNWN@561|Escherichia	1236|Gammaproteobacteria	O	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine	nrdG	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008998,GO:0009058,GO:0009117,GO:0009165,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0015949,GO:0016491,GO:0016725,GO:0016728,GO:0018130,GO:0019438,GO:0019637,GO:0019692,GO:0031250,GO:0032991,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046385,GO:0046483,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901576	1.97.1.4	ko:K04068	-	-	R04710	-	ko00000,ko01000	-	-	iE2348C_1286.E2348C_4563	Fer4_12
k141_3425_1	335541.Swol_1481	9.83e-110	322.0	COG2057@1|root,COG2057@2|Bacteria,1UDE4@1239|Firmicutes,24B51@186801|Clostridia,42KF9@68298|Syntrophomonadaceae	186801|Clostridia	H	COGs COG2057 Acyl CoA acetate 3-ketoacid CoA transferase beta subunit	-	-	2.8.3.12	ko:K01040	ko00643,ko00650,ko01120,map00643,map00650,map01120	-	R04000,R05509	RC00012,RC00131,RC00137	ko00000,ko00001,ko01000	-	-	-	CoA_trans
k141_2391_2	1517681.HW45_07425	5.88e-46	160.0	COG3106@1|root,COG3106@2|Bacteria,1MX6E@1224|Proteobacteria,1RQ05@1236|Gammaproteobacteria,1XT2C@135623|Vibrionales	135623|Vibrionales	S	YcjX-like family, DUF463	ycjX	-	-	ko:K06918	-	-	-	-	ko00000	-	-	-	DUF463
k141_3426_1	1121921.KB898706_gene3020	1.26e-22	90.1	2DPB2@1|root,331BY@2|Bacteria,1NBDA@1224|Proteobacteria,1SD6C@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_4447_1	177437.HRM2_43850	2.06e-205	575.0	COG2133@1|root,COG2133@2|Bacteria,1MV2E@1224|Proteobacteria,42QV3@68525|delta/epsilon subdivisions,2WMT2@28221|Deltaproteobacteria,2MKQZ@213118|Desulfobacterales	28221|Deltaproteobacteria	G	Glucose / Sorbosone dehydrogenase	-	-	-	ko:K21430	-	-	-	-	ko00000,ko01000	-	-	-	GSDH
k141_4447_2	243231.GSU0707	7.17e-47	152.0	COG2076@1|root,COG2076@2|Bacteria,1MZ6P@1224|Proteobacteria,42TM1@68525|delta/epsilon subdivisions,2WQK6@28221|Deltaproteobacteria,43VKK@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	Small Multidrug Resistance protein	-	-	-	ko:K11741	-	-	-	-	ko00000,ko02000	2.A.7.1	-	-	Multi_Drug_Res
k141_3427_1	658612.MD26_07525	1.1e-12	74.7	COG0840@1|root,COG0840@2|Bacteria,1RFH2@1224|Proteobacteria,1SMC2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	NT	chemotaxis, protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal
k141_4778_1	1419583.V466_14055	9.6e-41	144.0	COG0169@1|root,COG0169@2|Bacteria,1MY1Z@1224|Proteobacteria,1RRSP@1236|Gammaproteobacteria,1YNW3@136843|Pseudomonas fluorescens group	1236|Gammaproteobacteria	E	Shikimate	-	-	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	-	Shikimate_dh_N
k141_4778_2	944435.AXAJ01000002_gene4605	4.09e-73	224.0	COG1522@1|root,COG1522@2|Bacteria,1MX7R@1224|Proteobacteria,2VQ1S@28216|Betaproteobacteria,1K30H@119060|Burkholderiaceae	28216|Betaproteobacteria	K	PFAM regulatory protein AsnC Lrp family	-	GO:0001101,GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010033,GO:0010243,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0042221,GO:0043200,GO:0043565,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1901698,GO:1901700,GO:1903506,GO:2000112,GO:2001141	-	ko:K03719	-	-	-	-	ko00000,ko03000,ko03036	-	-	-	AsnC_trans_reg,HTH_24
k141_4778_3	345073.VC395_A0071	3.16e-258	724.0	COG0659@1|root,COG0659@2|Bacteria,1MVWV@1224|Proteobacteria,1RMCN@1236|Gammaproteobacteria,1XW6V@135623|Vibrionales	135623|Vibrionales	P	COG0659 Sulfate permease and related transporters (MFS superfamily)	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
k141_4778_5	1348635.BBJY01000014_gene842	1.95e-109	336.0	COG0737@1|root,COG0737@2|Bacteria,1MX03@1224|Proteobacteria,1RPX3@1236|Gammaproteobacteria,1XU8U@135623|Vibrionales	135623|Vibrionales	F	Belongs to the 5'-nucleotidase family	-	-	3.1.3.5	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	5_nucleotid_C,Metallophos
k141_4779_1	1379281.AVAG01000046_gene322	9.26e-54	190.0	COG1038@1|root,COG1038@2|Bacteria,1NW9R@1224|Proteobacteria,43BKE@68525|delta/epsilon subdivisions,2X6YE@28221|Deltaproteobacteria,2M8M5@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	Carbamoyl-phosphate synthetase large chain domain protein	-	-	6.4.1.1	ko:K01958	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	M00173	R00344	RC00040,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2,HMGL-like,PYC_OADA
k141_1749_2	55601.VANGNB10_cI1022c	3.03e-229	644.0	COG0134@1|root,COG0135@1|root,COG0134@2|Bacteria,COG0135@2|Bacteria,1MW5K@1224|Proteobacteria,1RNYH@1236|Gammaproteobacteria,1XSS7@135623|Vibrionales	135623|Vibrionales	E	Belongs to the TrpC family	trpC	GO:0000162,GO:0003674,GO:0003824,GO:0004425,GO:0004640,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016831,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.1.1.48,5.3.1.24	ko:K13498	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03508,R03509	RC00944,RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPS,PRAI
k141_1749_3	1348635.BBJY01000017_gene4118	1.23e-21	92.0	COG0547@1|root,COG0547@2|Bacteria,1MUPV@1224|Proteobacteria,1RNXV@1236|Gammaproteobacteria,1XT64@135623|Vibrionales	135623|Vibrionales	F	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)	trpD	GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.4.2.18	ko:K00766	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R01073	RC00440	ko00000,ko00001,ko00002,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3
k141_1750_3	754476.Q7A_917	2.67e-13	67.8	28KS3@1|root,2ZA9J@2|Bacteria,1R5YV@1224|Proteobacteria,1SMNA@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_4781_1	644282.Deba_1563	6.36e-56	188.0	COG0477@1|root,COG2814@2|Bacteria,1MW19@1224|Proteobacteria,42KZ4@68525|delta/epsilon subdivisions,2WKT2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	EGP	drug resistance transporter, Bcr CflA	-	-	-	ko:K07552	-	-	-	-	ko00000,ko02000	2.A.1.2	-	-	MFS_1
k141_3091_1	1236514.BAKL01000072_gene4483	6.76e-49	162.0	28PMV@1|root,2ZCAQ@2|Bacteria,4NMJQ@976|Bacteroidetes,2FM59@200643|Bacteroidia,4AME8@815|Bacteroidaceae	976|Bacteroidetes	S	COG NOG23385 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_2
k141_78_1	675814.VIC_002075	1.91e-138	400.0	COG1609@1|root,COG1609@2|Bacteria,1MU1G@1224|Proteobacteria,1RMSP@1236|Gammaproteobacteria,1XTZQ@135623|Vibrionales	135623|Vibrionales	K	transcriptional regulators	galR	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
k141_78_2	675812.VHA_002558	6.48e-150	433.0	COG2017@1|root,COG2017@2|Bacteria,1MVMN@1224|Proteobacteria,1RNZN@1236|Gammaproteobacteria,1XTI3@135623|Vibrionales	135623|Vibrionales	G	Converts alpha-aldose to the beta-anomer	galM	-	5.1.3.3	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	M00632	R01602,R10619	RC00563	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldose_epim
k141_78_3	1205908.AKXW01000065_gene2906	2.25e-217	607.0	COG0153@1|root,COG0153@2|Bacteria,1MVQD@1224|Proteobacteria,1RQ0C@1236|Gammaproteobacteria,1XUF3@135623|Vibrionales	135623|Vibrionales	F	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)	galK	GO:0003674,GO:0003824,GO:0004335,GO:0005975,GO:0005996,GO:0006012,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019200,GO:0019318,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0046835,GO:0071704	2.7.1.6	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00554,M00632	R01092	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	GHMP_kinases_C,GHMP_kinases_N,GalKase_gal_bdg
k141_78_4	1116375.VEJY3_22626	2.83e-239	659.0	COG1085@1|root,COG1085@2|Bacteria,1MU3E@1224|Proteobacteria,1RMDK@1236|Gammaproteobacteria,1XTKC@135623|Vibrionales	135623|Vibrionales	H	Galactose-1-phosphate uridylyltransferase	galT	-	2.7.7.12	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	M00362,M00554,M00632	R00955	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	GalP_UDP_tr_C,GalP_UDP_transf
k141_78_5	1116375.VEJY3_22631	2.54e-206	575.0	COG1087@1|root,COG1087@2|Bacteria,1MUHI@1224|Proteobacteria,1RMTU@1236|Gammaproteobacteria,1XSCZ@135623|Vibrionales	135623|Vibrionales	M	udp-glucose 4-epimerase	galE	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
k141_3428_1	1219077.VAZ01S_070_00030	1.49e-79	244.0	COG4171@1|root,COG4171@2|Bacteria,1QUAT@1224|Proteobacteria,1T1RQ@1236|Gammaproteobacteria,1XSV7@135623|Vibrionales	135623|Vibrionales	V	COG4171 ABC-type antimicrobial peptide transport system, permease component	sapC	-	-	ko:K19228	ko01503,ko02010,map01503,map02010	M00739	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.5	-	-	BPD_transp_1,OppC_N
k141_3428_2	55601.VANGNB10_cI1122c	1e-207	578.0	COG1123@1|root,COG4172@2|Bacteria,1MU09@1224|Proteobacteria,1RMEI@1236|Gammaproteobacteria,1XT4Q@135623|Vibrionales	135623|Vibrionales	P	Belongs to the ABC transporter superfamily	sapD	-	-	ko:K19229	ko01503,ko02010,map01503,map02010	M00739	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.5	-	-	ABC_tran,oligo_HPY
k141_3428_3	55601.VANGNB10_cI1121c	2.4e-150	427.0	COG1123@1|root,COG4172@2|Bacteria,1MU09@1224|Proteobacteria,1RMEI@1236|Gammaproteobacteria,1XTTI@135623|Vibrionales	135623|Vibrionales	P	ABC-type antimicrobial peptide transport system, ATPase component	sapF	-	-	ko:K19230	ko01503,ko02010,map01503,map02010	M00739	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.5	-	-	ABC_tran
k141_3428_4	675814.VIC_004486	4.41e-48	164.0	2BWZZ@1|root,2Z86E@2|Bacteria,1MW89@1224|Proteobacteria,1S85K@1236|Gammaproteobacteria,1XTRX@135623|Vibrionales	135623|Vibrionales	S	Protein of unknown function (DUF2927)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2927
k141_728_4	1211817.CCAT010000083_gene1573	9.18e-33	120.0	COG4939@1|root,COG4939@2|Bacteria,1VJ2S@1239|Firmicutes,24M0K@186801|Clostridia,36MA1@31979|Clostridiaceae	186801|Clostridia	S	FMN_bind	-	-	-	-	-	-	-	-	-	-	-	-	FMN_bind
k141_728_5	1008453.HMPREF9957_1031	8.03e-20	98.6	COG0477@1|root,COG2814@2|Bacteria,1VRUU@1239|Firmicutes,4HU3E@91061|Bacilli	91061|Bacilli	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
k141_728_7	580331.Thit_2151	1.79e-17	79.7	COG5341@1|root,COG5341@2|Bacteria,1VEPD@1239|Firmicutes,24QPH@186801|Clostridia,42GIW@68295|Thermoanaerobacterales	186801|Clostridia	S	NusG domain II	-	-	2.5.1.30	ko:K00805	ko00900,ko01110,map00900,map01110	-	R09247	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	-	NusG_II
k141_728_8	1280688.AUJB01000008_gene645	8.88e-32	119.0	COG4769@1|root,COG4769@2|Bacteria,1V1M0@1239|Firmicutes,24MZC@186801|Clostridia,3NHBS@46205|Pseudobutyrivibrio	186801|Clostridia	S	Heptaprenyl diphosphate synthase component I	-	-	2.5.1.30	ko:K00805	ko00900,ko01110,map00900,map01110	-	R09247	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	-	Hpre_diP_synt_I
k141_728_9	1487921.DP68_12030	6.14e-105	318.0	COG1477@1|root,COG1477@2|Bacteria,1TR9C@1239|Firmicutes,248KJ@186801|Clostridia,36DZZ@31979|Clostridiaceae	186801|Clostridia	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	apbE	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
k141_728_10	358681.BBR47_16050	1.41e-112	361.0	COG0840@1|root,COG0840@2|Bacteria,1TP5A@1239|Firmicutes,4H9RZ@91061|Bacilli,26QU5@186822|Paenibacillaceae	91061|Bacilli	NT	chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal,dCache_1
k141_2392_1	1121396.KB893077_gene755	3.16e-40	141.0	COG2020@1|root,COG2020@2|Bacteria	2|Bacteria	O	methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
k141_2392_2	411476.BACOVA_03808	2.74e-250	706.0	COG1132@1|root,COG1132@2|Bacteria,4NGTR@976|Bacteroidetes,2FN1P@200643|Bacteroidia,4AM37@815|Bacteroidaceae	976|Bacteroidetes	V	COG1132 ABC-type multidrug transport system, ATPase and permease components	ndvA	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
k141_742_1	96561.Dole_2534	8.05e-95	303.0	COG5009@1|root,COG5009@2|Bacteria,1MU5A@1224|Proteobacteria,42MJB@68525|delta/epsilon subdivisions,2WIXF@28221|Deltaproteobacteria,2MI9W@213118|Desulfobacterales	28221|Deltaproteobacteria	M	TIGRFAM penicillin-binding protein, 1A family	mrcA	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	iAF987.Gmet_0354	PCB_OB,Transgly,Transpeptidase
k141_3477_1	1304885.AUEY01000024_gene2728	4.41e-303	843.0	COG2414@1|root,COG2414@2|Bacteria,1MWBB@1224|Proteobacteria,42NR7@68525|delta/epsilon subdivisions,2WK49@28221|Deltaproteobacteria,2MHYC@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Aldehyde ferredoxin oxidoreductase	-	-	1.2.7.5	ko:K03738	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00309	R08571	RC00242	ko00000,ko00001,ko00002,ko01000	-	-	-	AFOR_C,AFOR_N
k141_3106_1	1191299.AJYX01000064_gene3501	6.06e-97	288.0	COG1489@1|root,COG1489@2|Bacteria,1MUC3@1224|Proteobacteria,1RQ95@1236|Gammaproteobacteria,1XTR1@135623|Vibrionales	135623|Vibrionales	S	Belongs to the SfsA family	sfsA	GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005975,GO:0008150,GO:0008152,GO:0044238,GO:0071704,GO:0097159,GO:1901363	-	ko:K06206	-	-	-	-	ko00000	-	-	-	SfsA
k141_4469_1	1304885.AUEY01000036_gene2265	3.39e-47	169.0	COG0443@1|root,COG0443@2|Bacteria,1MXX7@1224|Proteobacteria,42NWU@68525|delta/epsilon subdivisions,2WKQQ@28221|Deltaproteobacteria,2MIBJ@213118|Desulfobacterales	28221|Deltaproteobacteria	O	Belongs to the heat shock protein 70 family	dnaK4	-	-	-	-	-	-	-	-	-	-	-	HSP70
k141_4469_2	1304885.AUEY01000036_gene2264	1.88e-19	85.5	2CNUX@1|root,32SHU@2|Bacteria,1REYT@1224|Proteobacteria,42R1S@68525|delta/epsilon subdivisions,2WMRC@28221|Deltaproteobacteria,2MJPR@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF2760)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2760
k141_1422_1	933262.AXAM01000023_gene643	3.3e-74	244.0	COG0272@1|root,COG0272@2|Bacteria,1MV3R@1224|Proteobacteria,42MC5@68525|delta/epsilon subdivisions,2WIT5@28221|Deltaproteobacteria,2MJ0A@213118|Desulfobacterales	28221|Deltaproteobacteria	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
k141_98_1	1230342.CTM_21813	1.46e-54	177.0	COG0454@1|root,COG0456@2|Bacteria,1VHDN@1239|Firmicutes,24FXK@186801|Clostridia,36IBF@31979|Clostridiaceae	186801|Clostridia	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
k141_98_2	1304885.AUEY01000087_gene87	1.99e-94	281.0	COG3384@1|root,COG3384@2|Bacteria,1MXJZ@1224|Proteobacteria,42Q1N@68525|delta/epsilon subdivisions,2WK3A@28221|Deltaproteobacteria,2MICT@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Catalytic LigB subunit of aromatic ring-opening dioxygenase	ygiD	-	-	ko:K15777	ko00965,map00965	-	R08836	RC00387	ko00000,ko00001,ko01000	-	-	-	LigB
k141_4803_1	177437.HRM2_26820	1.68e-29	120.0	COG0768@1|root,COG0768@2|Bacteria,1R7A0@1224|Proteobacteria,42MJC@68525|delta/epsilon subdivisions,2WJZ2@28221|Deltaproteobacteria,2MJ2J@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Penicillin-binding Protein	pbp4	-	-	-	-	-	-	-	-	-	-	-	Transpeptidase
k141_743_2	1232437.KL661965_gene3230	2.95e-13	74.3	COG0532@1|root,COG0532@2|Bacteria,1MV26@1224|Proteobacteria,42M5Q@68525|delta/epsilon subdivisions,2WIIX@28221|Deltaproteobacteria,2MIGT@213118|Desulfobacterales	28221|Deltaproteobacteria	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,IF-2,IF2_N
k141_4804_1	879212.DespoDRAFT_00924	2.72e-75	242.0	COG4191@1|root,COG4191@2|Bacteria,1MY12@1224|Proteobacteria,42PID@68525|delta/epsilon subdivisions,2WJVW@28221|Deltaproteobacteria,2MI1P@213118|Desulfobacterales	28221|Deltaproteobacteria	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_9
k141_3478_1	244582.JQAK01000006_gene2287	2.58e-09	56.2	COG2963@1|root,COG2963@2|Bacteria,1N8W3@1224|Proteobacteria,2UBXZ@28211|Alphaproteobacteria,47GGB@766|Rickettsiales	766|Rickettsiales	L	Transposase	-	-	-	ko:K07483	-	-	-	-	ko00000	-	-	-	HTH_Tnp_1
k141_3478_2	1137799.GZ78_14485	4.6e-108	321.0	COG2801@1|root,COG2801@2|Bacteria,1MVC8@1224|Proteobacteria,1RXYF@1236|Gammaproteobacteria,1XHWD@135619|Oceanospirillales	135619|Oceanospirillales	L	HTH-like domain	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve,rve_3
k141_1423_2	1121396.KB893071_gene1297	6.57e-94	283.0	COG1242@1|root,COG1242@2|Bacteria,1MUYF@1224|Proteobacteria,42PX9@68525|delta/epsilon subdivisions,2WIPW@28221|Deltaproteobacteria,2MI53@213118|Desulfobacterales	28221|Deltaproteobacteria	S	PFAM Radical SAM domain protein	yhcC-1	-	-	ko:K07139	-	-	-	-	ko00000	-	-	-	Radical_SAM,Radical_SAM_C
k141_3479_1	329726.AM1_4475	9.54e-37	139.0	COG0399@1|root,COG0399@2|Bacteria,1G4PM@1117|Cyanobacteria	1117|Cyanobacteria	E	Belongs to the DegT DnrJ EryC1 family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
k141_100_1	207559.Dde_1151	4.56e-64	206.0	COG2206@1|root,COG2206@2|Bacteria,1RAQS@1224|Proteobacteria,42ZPB@68525|delta/epsilon subdivisions,2X76K@28221|Deltaproteobacteria,2MHA2@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_4470_1	1116375.VEJY3_06810	1.29e-33	126.0	COG0477@1|root,COG0477@2|Bacteria,1MU46@1224|Proteobacteria,1T3VZ@1236|Gammaproteobacteria,1XV7D@135623|Vibrionales	135623|Vibrionales	EGP	of the major facilitator superfamily	-	-	-	ko:K03762	-	-	-	-	ko00000,ko02000	2.A.1.6.4	-	-	MFS_1,Sugar_tr
k141_4470_2	1116375.VEJY3_06805	2.09e-221	613.0	COG0119@1|root,COG0119@2|Bacteria,1MVQG@1224|Proteobacteria,1RPPW@1236|Gammaproteobacteria,1XY9B@135623|Vibrionales	135623|Vibrionales	E	HMGL-like	-	-	4.1.3.39	ko:K01666	ko00360,ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00360,map00362,map00621,map00622,map01100,map01120,map01220	M00545,M00569	R00750	RC00307,RC00371	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	DmpG_comm,HMGL-like
k141_4470_3	1116375.VEJY3_06800	9.27e-60	192.0	COG4569@1|root,COG4569@2|Bacteria,1MV23@1224|Proteobacteria,1RNDJ@1236|Gammaproteobacteria,1Y02H@135623|Vibrionales	135623|Vibrionales	Q	Prokaryotic acetaldehyde dehydrogenase, dimerisation	-	-	1.2.1.10	ko:K04073	ko00360,ko00362,ko00620,ko00621,ko00622,ko00650,ko01100,ko01120,ko01220,map00360,map00362,map00620,map00621,map00622,map00650,map01100,map01120,map01220	M00545,M00569	R00228,R01172	RC00004,RC00184,RC01195	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	AcetDehyd-dimer,Semialdhyde_dh
k141_3108_1	177437.HRM2_03010	5.34e-47	162.0	COG1960@1|root,COG1960@2|Bacteria,1MU2V@1224|Proteobacteria,42NKV@68525|delta/epsilon subdivisions,2WKPA@28221|Deltaproteobacteria,2MIDW@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Acyl-CoA dehydrogenase, C-terminal domain	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
k141_744_1	675813.VIB_000620	8.58e-09	55.1	COG0564@1|root,COG0564@2|Bacteria,1MVJ5@1224|Proteobacteria,1RN4N@1236|Gammaproteobacteria,1XURW@135623|Vibrionales	135623|Vibrionales	J	Responsible for synthesis of pseudouridine from uracil	rluA	GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	5.4.99.28,5.4.99.29	ko:K06177	-	-	-	-	ko00000,ko01000,ko03009,ko03016	-	-	-	PseudoU_synth_2
k141_744_2	675814.VIC_004818	1.17e-163	465.0	COG1052@1|root,COG1052@2|Bacteria,1MU2D@1224|Proteobacteria,1RPM1@1236|Gammaproteobacteria,1XTHS@135623|Vibrionales	135623|Vibrionales	C	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family	hprA	-	1.1.1.29	ko:K00018	ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200	M00346	R00717,R01388	RC00031,RC00042	ko00000,ko00001,ko00002,ko01000	-	-	-	2-Hacid_dh,2-Hacid_dh_C
k141_744_3	1123400.KB904746_gene1328	6.75e-17	80.1	COG4269@1|root,COG4269@2|Bacteria,1MW5P@1224|Proteobacteria,1RY3G@1236|Gammaproteobacteria,462FN@72273|Thiotrichales	72273|Thiotrichales	S	Bacterial protein of unknown function (DUF898)	-	-	-	-	-	-	-	-	-	-	-	-	DUF898
k141_413_6	675815.VOA_003204	1.94e-105	316.0	COG4785@1|root,COG4785@2|Bacteria,1N02Y@1224|Proteobacteria,1RP8P@1236|Gammaproteobacteria,1XT95@135623|Vibrionales	135623|Vibrionales	M	May be involved in cell division	nlpI	-	-	ko:K05803	-	-	-	-	ko00000	-	-	-	TPR_8
k141_413_7	617140.AJZE01000012_gene2686	3.36e-142	421.0	COG0534@1|root,COG0534@2|Bacteria,1R4H5@1224|Proteobacteria,1RS0B@1236|Gammaproteobacteria,1XTRQ@135623|Vibrionales	135623|Vibrionales	V	Na driven multidrug efflux pump	vmrA	-	-	-	-	-	-	-	-	-	-	-	MatE
k141_413_8	2340.JV46_07750	5.79e-12	61.6	COG4679@1|root,COG4679@2|Bacteria,1MZ3N@1224|Proteobacteria,1S6QV@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Phage-related protein	-	-	-	-	-	-	-	-	-	-	-	-	Gp49
k141_413_9	298386.PBPRB0291	1.59e-24	94.7	COG4679@1|root,COG4679@2|Bacteria,1MZ3N@1224|Proteobacteria,1S6QV@1236|Gammaproteobacteria,1Y0VY@135623|Vibrionales	135623|Vibrionales	S	Phage derived protein Gp49-like (DUF891)	-	-	-	-	-	-	-	-	-	-	-	-	Gp49
k141_413_10	406817.XNC1_4123	1.23e-34	120.0	COG3620@1|root,COG3620@2|Bacteria,1N84U@1224|Proteobacteria,1T3G8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
k141_413_11	1280001.BAOA01000059_gene2268	2.05e-157	447.0	COG0826@1|root,COG0826@2|Bacteria,1MWFW@1224|Proteobacteria,1RMWM@1236|Gammaproteobacteria,1XT2K@135623|Vibrionales	135623|Vibrionales	O	COG0826 Collagenase and related proteases	yhbV	-	-	-	-	-	-	-	-	-	-	-	Peptidase_U32
k141_413_12	345073.VC395_0669	1.17e-197	553.0	COG0826@1|root,COG0826@2|Bacteria,1MUQG@1224|Proteobacteria,1RP6X@1236|Gammaproteobacteria,1XTKH@135623|Vibrionales	135623|Vibrionales	O	COG0826 Collagenase and related proteases	yhbU	-	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_U32
k141_413_13	675806.VII_003098	1.6e-297	835.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1XSRH@135623|Vibrionales	135623|Vibrionales	T	signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	VV2690	-	3.1.4.52	ko:K20965	ko05111,map05111	-	-	-	ko00000,ko00001,ko01000	-	-	-	EAL,GGDEF,PAS_4,PAS_8,PAS_9
k141_413_14	945543.VIBR0546_02031	4.51e-25	99.0	COG3154@1|root,COG3154@2|Bacteria,1MZNC@1224|Proteobacteria,1S9BQ@1236|Gammaproteobacteria,1XUWR@135623|Vibrionales	135623|Vibrionales	I	lipid carrier protein	-	-	-	-	-	-	-	-	-	-	-	-	SCP2
k141_102_1	675816.VIA_003131	5.34e-135	399.0	COG1061@1|root,COG1061@2|Bacteria,1MV9F@1224|Proteobacteria,1RNAN@1236|Gammaproteobacteria,1XV70@135623|Vibrionales	135623|Vibrionales	KL	COG1061 DNA or RNA helicases of superfamily II	yejH	-	-	ko:K19789	-	-	-	-	ko00000,ko03400	-	-	-	Helicase_C,ResIII
k141_4807_1	1463845.JOIG01000014_gene44	0.000709	48.9	COG2909@1|root,COG2909@2|Bacteria,2GJAR@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GerE
k141_2066_3	1348635.BBJY01000010_gene1324	1.1e-263	733.0	COG2721@1|root,COG2721@2|Bacteria,1MU9V@1224|Proteobacteria,1RP0M@1236|Gammaproteobacteria,1XW7T@135623|Vibrionales	135623|Vibrionales	G	COG2721 Altronate dehydratase	-	-	4.2.1.7	ko:K01685	ko00040,ko01100,map00040,map01100	M00631	R01540	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	-	GD_AH_C,SAF
k141_2066_4	1348635.BBJY01000010_gene1325	1.39e-231	651.0	COG0246@1|root,COG0246@2|Bacteria,1MVZ7@1224|Proteobacteria,1RQX5@1236|Gammaproteobacteria,1XUJB@135623|Vibrionales	135623|Vibrionales	C	Mannitol dehydrogenase C-terminal domain	-	-	1.1.1.58	ko:K00041	ko00040,ko01100,map00040,map01100	M00631	R02555	RC00085	ko00000,ko00001,ko00002,ko01000	-	-	-	Mannitol_dh,Mannitol_dh_C
k141_2066_5	1348635.BBJY01000010_gene1326	1.12e-273	756.0	COG1904@1|root,COG1904@2|Bacteria,1MVRI@1224|Proteobacteria,1RMRR@1236|Gammaproteobacteria,1XTDU@135623|Vibrionales	135623|Vibrionales	G	glucuronate isomerase activity	uxaC	-	5.3.1.12	ko:K01812	ko00040,ko01100,map00040,map01100	M00061,M00631	R01482,R01983	RC00376	ko00000,ko00001,ko00002,ko01000	-	-	-	UxaC
k141_2066_6	1267600.JFGT01000002_gene891	1.15e-165	471.0	COG1638@1|root,COG1638@2|Bacteria,1MVHC@1224|Proteobacteria,1RPNJ@1236|Gammaproteobacteria,3VYVF@53335|Pantoea	1236|Gammaproteobacteria	G	Bacterial extracellular solute-binding protein, family 7	dctP	-	-	-	-	-	-	-	-	-	-	-	DctP
k141_2066_7	1267600.JFGT01000002_gene892	2.94e-59	189.0	COG3090@1|root,COG3090@2|Bacteria,1RJ8K@1224|Proteobacteria,1SA02@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	TRAP-type C4-dicarboxylate transport system small permease component	-	-	-	-	-	-	-	-	-	-	-	-	DctQ
k141_2066_8	1267600.JFGT01000002_gene893	3.34e-236	658.0	COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,1RNAM@1236|Gammaproteobacteria,3VYJT@53335|Pantoea	1236|Gammaproteobacteria	G	Tripartite ATP-independent periplasmic transporter, DctM component	-	-	-	-	-	-	-	-	-	-	-	-	DctM
k141_2066_9	342610.Patl_2503	3e-24	104.0	COG0847@1|root,COG0847@2|Bacteria,1RAF1@1224|Proteobacteria,1S20V@1236|Gammaproteobacteria,2Q2K0@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	L	DNA polymerase III	-	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	RNase_T
k141_2066_10	675813.VIB_002435	0.0	973.0	COG2905@1|root,COG2905@2|Bacteria,1MW8U@1224|Proteobacteria,1RPSJ@1236|Gammaproteobacteria,1XTPG@135623|Vibrionales	135623|Vibrionales	T	containing cAMP-binding and CBS domains	-	-	-	ko:K07182	-	-	-	-	ko00000	-	-	-	CBS,DUF294,DUF294_C,cNMP_binding
k141_2066_11	672.VV93_v1c43090	2.94e-140	401.0	COG1414@1|root,COG1414@2|Bacteria,1MUNW@1224|Proteobacteria,1RR06@1236|Gammaproteobacteria,1XU1E@135623|Vibrionales	135623|Vibrionales	K	helix_turn_helix isocitrate lyase regulation	kdgR	-	-	ko:K19333,ko:K21602	-	-	-	-	ko00000,ko03000	-	-	-	HTH_IclR,IclR
k141_4190_3	1121936.AUHI01000006_gene2035	8.78e-12	76.6	COG0840@1|root,COG0840@2|Bacteria,1TP5A@1239|Firmicutes,4H9RZ@91061|Bacilli	91061|Bacilli	NT	chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal,dCache_1
k141_4190_4	1540257.JQMW01000013_gene1163	7.08e-228	641.0	COG1115@1|root,COG1115@2|Bacteria,1TNZP@1239|Firmicutes,247S6@186801|Clostridia,36F13@31979|Clostridiaceae	186801|Clostridia	E	amino acid carrier protein	glnT	-	-	ko:K03310	-	-	-	-	ko00000	2.A.25	-	-	Na_Ala_symp
k141_4190_6	1259795.ARJK01000003_gene1041	7.76e-23	92.4	2E6A2@1|root,330XY@2|Bacteria,1U5UB@1239|Firmicutes,25NDK@186801|Clostridia,42IJU@68295|Thermoanaerobacterales	186801|Clostridia	S	Coenzyme PQQ synthesis protein D (PqqD)	-	-	-	-	-	-	-	-	-	-	-	-	PqqD
k141_4190_7	1347392.CCEZ01000019_gene1031	1.42e-262	744.0	COG1297@1|root,COG1297@2|Bacteria,1TQJP@1239|Firmicutes,247JY@186801|Clostridia,36DEB@31979|Clostridiaceae	186801|Clostridia	S	oligopeptide transporter, OPT family	-	-	-	-	-	-	-	-	-	-	-	-	OPT
k141_1480_2	1121428.DESHY_40162___1	4.74e-55	184.0	COG2122@1|root,COG2122@2|Bacteria,1TQ6A@1239|Firmicutes,249KT@186801|Clostridia,260Y4@186807|Peptococcaceae	186801|Clostridia	S	PFAM ApbE family	-	-	-	ko:K09740	-	-	-	-	ko00000	-	-	-	-
k141_1480_3	1304885.AUEY01000095_gene2625	2.68e-21	93.6	COG0210@1|root,COG0210@2|Bacteria,1MU0G@1224|Proteobacteria,42MKU@68525|delta/epsilon subdivisions,2WJR3@28221|Deltaproteobacteria,2MI3D@213118|Desulfobacterales	28221|Deltaproteobacteria	L	UvrD REP helicase	pcrA	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
k141_1491_1	643562.Daes_1172	8.67e-91	276.0	COG3639@1|root,COG3639@2|Bacteria,1MW4F@1224|Proteobacteria,42TK6@68525|delta/epsilon subdivisions,2WMDD@28221|Deltaproteobacteria,2M8X4@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	TIGRFAM phosphonate ABC transporter, inner membrane subunit	phnE	-	-	ko:K02042	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	BPD_transp_1
k141_1491_2	1217718.ALOU01000058_gene731	8.73e-24	97.8	COG3624@1|root,COG3624@2|Bacteria,1MZTZ@1224|Proteobacteria,2VV43@28216|Betaproteobacteria,1K7UB@119060|Burkholderiaceae	28216|Betaproteobacteria	P	Phosphonate C-P lyase system protein PhnG	phnG	-	2.7.8.37	ko:K06166	ko00440,map00440	-	R10185	RC00005,RC00063	ko00000,ko00001,ko01000	-	-	-	PhnG
k141_1491_3	1187848.AJYQ01000077_gene1783	1.23e-26	108.0	COG3625@1|root,COG3625@2|Bacteria,1RHXN@1224|Proteobacteria,1RZR8@1236|Gammaproteobacteria,1XXD1@135623|Vibrionales	135623|Vibrionales	P	Bacterial phosphonate metabolism protein (PhnH)	-	-	2.7.8.37	ko:K06165	ko00440,map00440	-	R10185	RC00005,RC00063	ko00000,ko00001,ko01000	-	-	-	PhnH
k141_1491_4	1541065.JRFE01000010_gene4308	5.89e-121	366.0	COG3153@1|root,COG3626@1|root,COG3153@2|Bacteria,COG3626@2|Bacteria,1G9IB@1117|Cyanobacteria,3VK95@52604|Pleurocapsales	1117|Cyanobacteria	P	PFAM Acetyltransferase (GNAT) family	-	-	-	ko:K03824	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_9
k141_1491_5	1336243.JAEA01000001_gene2063	4.51e-65	206.0	COG3627@1|root,COG3627@2|Bacteria,1MV7T@1224|Proteobacteria,2TRKP@28211|Alphaproteobacteria,1JSGT@119045|Methylobacteriaceae	28211|Alphaproteobacteria	P	Catalyzes the breakage of the C-P bond in alpha-D-ribose 1-methylphosphonate 5-phosphate (PRPn) forming alpha-D-ribose	phnJ	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0006793,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016829,GO:0018835,GO:0019634,GO:0019637,GO:0019700,GO:0032991,GO:0044237,GO:0046434,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:0098848,GO:1901575,GO:1902494,GO:1904176	4.7.1.1	ko:K06163	ko00440,map00440	-	R10204	RC03078,RC03079	ko00000,ko00001,ko01000	-	-	-	PhnJ
k141_2824_1	342610.Patl_2665	0.000119	52.4	COG5001@1|root,COG5001@2|Bacteria,1PRV9@1224|Proteobacteria,1RZHM@1236|Gammaproteobacteria,2Q1DN@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
k141_2824_4	1515746.HR45_08740	1.09e-93	276.0	COG0716@1|root,COG0716@2|Bacteria,1MX7F@1224|Proteobacteria,1RMNT@1236|Gammaproteobacteria,2Q8XW@267890|Shewanellaceae	1236|Gammaproteobacteria	C	Low-potential electron donor to a number of redox enzymes	nifF	-	-	ko:K03839	-	-	-	-	ko00000	-	-	-	Flavodoxin_1
k141_233_1	674977.VMC_29240	2.78e-64	197.0	COG1539@1|root,COG1539@2|Bacteria,1MZ8Z@1224|Proteobacteria,1S9B2@1236|Gammaproteobacteria,1XXCM@135623|Vibrionales	135623|Vibrionales	H	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin	folB	-	1.13.11.81,4.1.2.25,5.1.99.8	ko:K01633	ko00790,ko01100,map00790,map01100	M00126,M00840	R03504,R11037,R11073	RC00721,RC00943,RC01479,RC03333,RC03334	ko00000,ko00001,ko00002,ko01000	-	-	-	FolB
k141_233_2	243277.VC_0525	2.51e-58	187.0	COG0801@1|root,COG0801@2|Bacteria,1RHNN@1224|Proteobacteria,1S62M@1236|Gammaproteobacteria,1XXCH@135623|Vibrionales	135623|Vibrionales	H	COG0801 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase	folK-1	-	2.7.6.3	ko:K00950	ko00790,ko01100,map00790,map01100	M00126,M00841	R03503	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HPPK
k141_233_3	998674.ATTE01000001_gene2830	1.17e-112	331.0	COG1968@1|root,COG1968@2|Bacteria,1MX02@1224|Proteobacteria,1RQQT@1236|Gammaproteobacteria,4607N@72273|Thiotrichales	72273|Thiotrichales	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
k141_233_4	870967.VIS19158_21701	4.21e-45	147.0	COG2919@1|root,COG2919@2|Bacteria,1N7AA@1224|Proteobacteria,1SD8H@1236|Gammaproteobacteria,1XYBX@135623|Vibrionales	135623|Vibrionales	D	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic	ftsB	-	-	ko:K05589	-	-	-	-	ko00000,ko03036	-	-	-	DivIC
k141_233_5	575788.VS_2605	2.47e-103	305.0	COG1211@1|root,COG1211@2|Bacteria,1MY3B@1224|Proteobacteria,1S21S@1236|Gammaproteobacteria,1XTAS@135623|Vibrionales	135623|Vibrionales	I	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)	ispD	GO:0003674,GO:0003824,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0050518,GO:0070567,GO:0071704,GO:1901576	2.7.7.60	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD
k141_233_7	675813.VIB_002020	1.57e-175	498.0	COG0585@1|root,COG0585@2|Bacteria,1MXHD@1224|Proteobacteria,1RPRF@1236|Gammaproteobacteria,1XTNP@135623|Vibrionales	135623|Vibrionales	J	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs	truD	GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0016070,GO:0016853,GO:0016866,GO:0034641,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360	5.4.99.27	ko:K06176	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruD
k141_233_8	1348635.BBJY01000002_gene3640	2.99e-143	408.0	COG0496@1|root,COG0496@2|Bacteria,1MVHE@1224|Proteobacteria,1RN36@1236|Gammaproteobacteria,1XT84@135623|Vibrionales	135623|Vibrionales	S	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates	surE	-	3.1.3.5	ko:K03787	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	SurE
k141_233_9	1219065.VPR01S_28_00490	1.77e-110	322.0	COG2518@1|root,COG2518@2|Bacteria,1MXQC@1224|Proteobacteria,1RMHZ@1236|Gammaproteobacteria,1XUP9@135623|Vibrionales	135623|Vibrionales	J	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	pcm	GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0030091,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
k141_233_10	672.VV93_v1c25200	3.02e-12	65.5	COG1388@1|root,COG4942@1|root,COG1388@2|Bacteria,COG4942@2|Bacteria,1RD24@1224|Proteobacteria,1RR11@1236|Gammaproteobacteria,1XSDC@135623|Vibrionales	135623|Vibrionales	M	COG0739 Membrane proteins related to metalloendopeptidases	nlpD	-	-	ko:K06194	-	-	-	-	ko00000	1.A.34.1.2	-	-	LysM,Peptidase_M23
k141_2181_1	1304885.AUEY01000009_gene1985	1.73e-17	79.7	2E2J5@1|root,32XNP@2|Bacteria,1N5QE@1224|Proteobacteria,42TX1@68525|delta/epsilon subdivisions,2WQTE@28221|Deltaproteobacteria,2MKKI@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_3211_1	439235.Dalk_4625	3.43e-32	119.0	COG2109@1|root,COG2109@2|Bacteria,1MUN6@1224|Proteobacteria,42RPD@68525|delta/epsilon subdivisions,2WNI0@28221|Deltaproteobacteria,2MK1B@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids	-	-	2.5.1.17	ko:K19221	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	CobA_CobO_BtuR
k141_2182_1	1506994.JNLQ01000002_gene1517	2.94e-26	116.0	COG5001@1|root,COG5001@2|Bacteria,1TP8V@1239|Firmicutes,247PX@186801|Clostridia,4BYFJ@830|Butyrivibrio	186801|Clostridia	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
k141_2182_2	1288.SXYLSMQ121_0266	1.65e-18	83.2	COG1946@1|root,COG1946@2|Bacteria,1V302@1239|Firmicutes,4HG3J@91061|Bacilli,4GYQ6@90964|Staphylococcaceae	91061|Bacilli	I	Thioesterase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT_3
k141_2825_1	1454202.PPBDW_100071___1	4.71e-67	216.0	COG3681@1|root,COG3681@2|Bacteria,1MW81@1224|Proteobacteria,1RP1R@1236|Gammaproteobacteria,1XUWS@135623|Vibrionales	135623|Vibrionales	S	Belongs to the UPF0597 family	-	-	-	-	-	-	-	-	-	-	-	-	SDH_alpha
k141_2825_2	1265503.KB905170_gene167	1.39e-12	69.7	COG3344@1|root,COG3344@2|Bacteria,1R44F@1224|Proteobacteria,1S05V@1236|Gammaproteobacteria,2Q8FB@267889|Colwelliaceae	1236|Gammaproteobacteria	L	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	RVT_1
k141_3212_1	1211579.PP4_11670	5.86e-08	62.4	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	NT	chemotaxis, protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal,dCache_1,dCache_2,sCache_2
k141_538_1	1173024.KI912153_gene315	2.34e-05	47.4	COG0403@1|root,COG1003@1|root,COG0403@2|Bacteria,COG1003@2|Bacteria,1G1HW@1117|Cyanobacteria,1JIBX@1189|Stigonemataceae	1117|Cyanobacteria	E	Glycine cleavage system P-protein	gcvP	-	1.4.4.2	ko:K00281	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko00002,ko01000	-	-	-	GDC-P
k141_538_2	1265503.KB905162_gene3485	6.17e-44	147.0	COG0509@1|root,COG0509@2|Bacteria,1RGV7@1224|Proteobacteria,1S656@1236|Gammaproteobacteria,2Q6WK@267889|Colwelliaceae	1236|Gammaproteobacteria	E	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein	gcvH	GO:0001505,GO:0003674,GO:0005488,GO:0005504,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006544,GO:0006546,GO:0006807,GO:0008150,GO:0008152,GO:0008289,GO:0009056,GO:0009063,GO:0009069,GO:0009071,GO:0009987,GO:0016054,GO:0017144,GO:0019464,GO:0019752,GO:0031405,GO:0031406,GO:0033293,GO:0036094,GO:0042133,GO:0042135,GO:0042737,GO:0043167,GO:0043168,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0048037,GO:0050662,GO:0065007,GO:0065008,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606,GO:1901681	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	iE2348C_1286.E2348C_3156,iPC815.YPO0906	GCV_H
k141_538_3	55601.VANGNB10_cII0256	5.25e-118	340.0	COG1426@1|root,COG1426@2|Bacteria,1QUH8@1224|Proteobacteria,1RQEE@1236|Gammaproteobacteria,1XSYT@135623|Vibrionales	135623|Vibrionales	K	transcriptional	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,HTH_3
k141_538_4	55601.VANGNB10_cII0257	1.71e-184	523.0	COG0404@1|root,COG0404@2|Bacteria,1MV96@1224|Proteobacteria,1RN2A@1236|Gammaproteobacteria,1XSK0@135623|Vibrionales	135623|Vibrionales	H	COG0404 Glycine cleavage system T protein (aminomethyltransferase)	gcvT	-	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
k141_538_5	345073.VC395_A0825	2.8e-226	633.0	COG0524@1|root,COG0524@2|Bacteria,1MUUC@1224|Proteobacteria,1RMN2@1236|Gammaproteobacteria,1XT8M@135623|Vibrionales	135623|Vibrionales	G	COG0524 Sugar kinases, ribokinase family	-	-	2.7.1.73	ko:K00892	ko00230,map00230	-	R01131,R01228	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
k141_538_6	1219080.VEZ01S_20_01190	6.9e-77	234.0	COG3045@1|root,COG3045@2|Bacteria,1RDI5@1224|Proteobacteria,1T060@1236|Gammaproteobacteria,1XWVW@135623|Vibrionales	135623|Vibrionales	S	CreA protein	creA	-	-	ko:K05805	-	-	-	-	ko00000	-	-	-	CreA
k141_538_7	945550.VISI1226_09964	2.01e-40	141.0	2AXJM@1|root,31PJR@2|Bacteria,1QJUS@1224|Proteobacteria,1THW8@1236|Gammaproteobacteria,1XXQC@135623|Vibrionales	135623|Vibrionales	-	-	VV20220	-	-	-	-	-	-	-	-	-	-	-	-
k141_538_9	1219065.VPR01S_07_01580	7.37e-39	132.0	COG1324@1|root,COG1324@2|Bacteria,1N6TN@1224|Proteobacteria,1SCFM@1236|Gammaproteobacteria,1XYEG@135623|Vibrionales	135623|Vibrionales	P	protein involved in tolerance to divalent cations	cutA	-	-	ko:K03926	-	-	-	-	ko00000	-	-	-	CutA1
k141_538_10	55601.VANGNB10_cII0748	2.93e-82	249.0	COG3647@1|root,COG3647@2|Bacteria,1N7NB@1224|Proteobacteria,1S6G7@1236|Gammaproteobacteria,1XV3H@135623|Vibrionales	135623|Vibrionales	S	membrane	-	-	-	ko:K08984	-	-	-	-	ko00000	-	-	-	DUF2238
k141_538_11	205914.HS_0818	1.11e-10	67.8	COG1718@1|root,COG1718@2|Bacteria	2|Bacteria	DT	cellular response to dsDNA	-	-	-	-	-	-	-	-	-	-	-	-	Kdo,RIO1
k141_538_12	1051646.VITU9109_01677	5.57e-87	262.0	COG2214@1|root,COG2214@2|Bacteria,1N0S7@1224|Proteobacteria,1SAFR@1236|Gammaproteobacteria,1XTJX@135623|Vibrionales	135623|Vibrionales	O	COG2214 DnaJ-class molecular chaperone	-	-	-	-	-	-	-	-	-	-	-	-	DNAJ_related,DnaJ
k141_538_13	55601.VANGNB10_cII0745	6.55e-162	485.0	COG2199@1|root,COG2200@1|root,COG2203@1|root,COG2199@2|Bacteria,COG2200@2|Bacteria,COG2203@2|Bacteria,1RGKE@1224|Proteobacteria,1T1I8@1236|Gammaproteobacteria,1XUWZ@135623|Vibrionales	135623|Vibrionales	T	GGDEF family	-	-	3.1.4.52	ko:K20962	ko05111,map05111	-	-	-	ko00000,ko00001,ko01000	-	-	-	EAL,GAF,GAF_2,GGDEF
k141_538_14	357804.Ping_2959	1.07e-77	238.0	COG2755@1|root,COG2755@2|Bacteria,1RCXZ@1224|Proteobacteria,1S3QU@1236|Gammaproteobacteria,2QIWE@267894|Psychromonadaceae	1236|Gammaproteobacteria	E	GDSL-like Lipase/Acylhydrolase family	tesA	GO:0003674,GO:0003824,GO:0004620,GO:0004622,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016289,GO:0016290,GO:0016298,GO:0016787,GO:0016788,GO:0016790,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0042802,GO:0043170,GO:0044238,GO:0044464,GO:0047617,GO:0052689,GO:0071704,GO:0140096,GO:1901564	3.1.1.5	ko:K10804	ko01040,map01040	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	iECED1_1282.ECED1_0521,iLF82_1304.LF82_2242,iNRG857_1313.NRG857_02365	Lipase_GDSL_2
k141_538_15	1188252.AJYK01000066_gene2468	1.02e-85	261.0	COG4181@1|root,COG4181@2|Bacteria,1MXG9@1224|Proteobacteria,1RMG1@1236|Gammaproteobacteria,1XU0B@135623|Vibrionales	135623|Vibrionales	Q	ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component	ybbA	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
k141_538_16	1348635.BBJY01000014_gene914	9.64e-244	707.0	COG3127@1|root,COG3127@2|Bacteria,1MU9R@1224|Proteobacteria,1RM8Y@1236|Gammaproteobacteria,1XSX0@135623|Vibrionales	135623|Vibrionales	Q	ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX
k141_538_19	675806.VII_001074	1.17e-209	583.0	COG1087@1|root,COG1087@2|Bacteria,1MUHI@1224|Proteobacteria,1RMTU@1236|Gammaproteobacteria,1XSCZ@135623|Vibrionales	135623|Vibrionales	M	udp-glucose 4-epimerase	galE	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
k141_538_20	1348635.BBJY01000014_gene905	9.02e-59	190.0	COG3124@1|root,COG3124@2|Bacteria,1MZ59@1224|Proteobacteria,1S9IZ@1236|Gammaproteobacteria,1XX07@135623|Vibrionales	135623|Vibrionales	S	protein conserved in bacteria	acpH	-	3.1.4.14	ko:K08682	ko00770,map00770	-	R01623	-	ko00000,ko00001,ko01000	-	-	-	ACP_PD
k141_538_21	870967.VIS19158_07000	2.77e-64	208.0	COG1309@1|root,COG1309@2|Bacteria,1RGTT@1224|Proteobacteria,1S6VQ@1236|Gammaproteobacteria,1Y26C@135623|Vibrionales	135623|Vibrionales	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
k141_538_22	1348635.BBJY01000014_gene901	4.84e-78	236.0	COG0494@1|root,COG0494@2|Bacteria,1RCX7@1224|Proteobacteria,1RSM2@1236|Gammaproteobacteria,1XX52@135623|Vibrionales	135623|Vibrionales	L	COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes	-	-	3.6.1.13	ko:K01515	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
k141_538_23	945550.VISI1226_04532	6.18e-260	728.0	COG0714@1|root,COG0714@2|Bacteria,1PC08@1224|Proteobacteria,1RQ5U@1236|Gammaproteobacteria,1XSDT@135623|Vibrionales	135623|Vibrionales	S	COG0714 MoxR-like ATPases	ravA	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_5,DUF3763
k141_538_24	1280001.BAOA01000072_gene2787	2.78e-229	645.0	COG2425@1|root,COG2425@2|Bacteria,1N1RQ@1224|Proteobacteria,1RPQT@1236|Gammaproteobacteria,1XTJ0@135623|Vibrionales	135623|Vibrionales	S	protein containing a von Willebrand factor type A (vWA) domain	yieM	-	-	-	-	-	-	-	-	-	-	-	VWA_CoxE
k141_538_25	458817.Shal_3718	5.23e-86	273.0	COG0738@1|root,COG0738@2|Bacteria,1QUEB@1224|Proteobacteria,1T1VW@1236|Gammaproteobacteria,2Q95V@267890|Shewanellaceae	1236|Gammaproteobacteria	G	PFAM major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
k141_538_26	345073.VC395_A0562	2.19e-68	210.0	COG3118@1|root,COG3118@2|Bacteria,1RHUA@1224|Proteobacteria,1S64W@1236|Gammaproteobacteria,1XWV6@135623|Vibrionales	135623|Vibrionales	O	COG0526 Thiol-disulfide isomerase and thioredoxins	trxC	-	1.8.1.8	ko:K03672	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Thioredoxin
k141_538_29	675813.VIB_002389	2.8e-82	250.0	COG3132@1|root,COG3132@2|Bacteria,1RA13@1224|Proteobacteria,1RQUQ@1236|Gammaproteobacteria,1XUQY@135623|Vibrionales	135623|Vibrionales	S	Belongs to the UPF0502 family	yceH	-	-	ko:K09915	-	-	-	-	ko00000	-	-	-	DUF480
k141_538_30	932677.PAJ_3617	1.44e-20	85.9	COG2827@1|root,COG2827@2|Bacteria,1N6PA@1224|Proteobacteria,1SCBH@1236|Gammaproteobacteria,3W1A0@53335|Pantoea	1236|Gammaproteobacteria	L	Excinuclease ABC C subunit domain protein	yhbQ	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004527,GO:0004529,GO:0004536,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008296,GO:0008408,GO:0009987,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360	-	ko:K07461	-	-	-	-	ko00000	-	-	-	GIY-YIG
k141_538_31	675813.VIB_000195	1.72e-34	120.0	2AXT7@1|root,31PU6@2|Bacteria,1QMH5@1224|Proteobacteria,1TJSH@1236|Gammaproteobacteria,1Y1MF@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_538_32	945543.VIBR0546_11752	2.44e-115	333.0	COG0705@1|root,COG0705@2|Bacteria,1RANX@1224|Proteobacteria,1S2I5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Rhomboid family	-	-	3.4.21.105	ko:K19225	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Rhomboid
k141_538_33	575788.VS_1588	7.38e-80	239.0	COG0454@1|root,COG0456@2|Bacteria,1RA6D@1224|Proteobacteria,1S8VJ@1236|Gammaproteobacteria,1XX7T@135623|Vibrionales	135623|Vibrionales	K	FR47-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
k141_538_35	312309.VF_2604	1.69e-22	87.0	2C7CM@1|root,33DFK@2|Bacteria,1NMRB@1224|Proteobacteria,1SIJ7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_538_36	945550.VISI1226_12381	2.98e-45	152.0	COG0454@1|root,COG0456@2|Bacteria,1N2H5@1224|Proteobacteria,1SBK2@1236|Gammaproteobacteria,1XXU7@135623|Vibrionales	135623|Vibrionales	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
k141_538_37	575788.VS_1550	1.82e-139	395.0	COG0637@1|root,COG0637@2|Bacteria,1RCD8@1224|Proteobacteria,1SDYG@1236|Gammaproteobacteria,1XUD1@135623|Vibrionales	135623|Vibrionales	S	Haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
k141_538_38	1122243.KB903792_gene1701	2.56e-37	129.0	COG2105@1|root,COG2105@2|Bacteria,1MZ4Y@1224|Proteobacteria,1SA6T@1236|Gammaproteobacteria,3NRQ2@468|Moraxellaceae	1236|Gammaproteobacteria	S	Gamma-glutamyl cyclotransferase, AIG2-like	-	-	-	-	-	-	-	-	-	-	-	-	GGACT
k141_3547_2	1280689.AUJC01000004_gene341	6.2e-173	532.0	COG3325@1|root,COG3325@2|Bacteria,1UPJ7@1239|Firmicutes,24D95@186801|Clostridia,36EAZ@31979|Clostridiaceae	186801|Clostridia	G	Belongs to the glycosyl hydrolase 18 family	-	-	3.2.1.14	ko:K01183	ko00520,ko01100,map00520,map01100	-	R01206,R02334	RC00467	ko00000,ko00001,ko01000	-	GH18	-	CHB_HEX_C_1,ChitinaseA_N,Glyco_hydro_18
k141_2826_1	1133849.O3I_012595	1.05e-15	86.7	COG2936@1|root,COG2936@2|Bacteria,2GK8B@201174|Actinobacteria,4FY39@85025|Nocardiaceae	201174|Actinobacteria	S	acyl esterases	-	-	-	ko:K06978	-	-	-	-	ko00000	-	-	-	PepX_C,Peptidase_S15
k141_3892_1	1348635.BBJY01000015_gene684	2.73e-93	284.0	COG3437@1|root,COG3437@2|Bacteria,1MUB8@1224|Proteobacteria,1RPH3@1236|Gammaproteobacteria,1XT5R@135623|Vibrionales	135623|Vibrionales	T	COG3437 Response regulator containing a CheY-like receiver domain and an HD-GYP domain	-	-	-	ko:K07814	-	-	-	-	ko00000,ko02022	-	-	-	HD,HD_5,Response_reg
k141_3892_2	930166.CD58_11520	4.48e-121	362.0	COG0624@1|root,COG0624@2|Bacteria,1MVBR@1224|Proteobacteria,1RNDG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Belongs to the peptidase M20A family. ArgE subfamily	argE	-	3.5.1.16	ko:K01438	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R00669,R09107	RC00064,RC00300	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20
k141_3892_3	29495.EA26_10105	1.14e-109	324.0	COG0697@1|root,COG0697@2|Bacteria,1MVKG@1224|Proteobacteria,1RM8T@1236|Gammaproteobacteria,1XSWG@135623|Vibrionales	135623|Vibrionales	EG	of the drug metabolite transporter (DMT) superfamily	-	-	-	ko:K15268	-	-	-	-	ko00000,ko02000	2.A.7.3.2	-	-	EamA
k141_2184_1	316067.Geob_0168	3.5e-148	446.0	COG3604@1|root,COG3604@2|Bacteria,1QTT3@1224|Proteobacteria,42Y50@68525|delta/epsilon subdivisions,2WUBF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	KT	PFAM sigma-54 factor interaction domain-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,GAF_3,HTH_8,PAS_4,Sigma54_activat
k141_2185_1	247490.KSU1_B0159	1.78e-20	95.9	COG2203@1|root,COG4191@1|root,COG2203@2|Bacteria,COG4191@2|Bacteria,2IWUM@203682|Planctomycetes	203682|Planctomycetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
k141_1889_1	1121405.dsmv_1598	1.85e-251	703.0	COG0442@1|root,COG0442@2|Bacteria,1MU7E@1224|Proteobacteria,42ME5@68525|delta/epsilon subdivisions,2WJVC@28221|Deltaproteobacteria,2MINJ@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro)	proS	-	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,ProRS-C_1,tRNA-synt_2b
k141_1889_2	439235.Dalk_5107	2.9e-288	813.0	COG0317@1|root,COG0317@2|Bacteria,1MU44@1224|Proteobacteria,42M6W@68525|delta/epsilon subdivisions,2WIZF@28221|Deltaproteobacteria,2MIKW@213118|Desulfobacterales	28221|Deltaproteobacteria	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	relA	-	2.7.6.5	ko:K00951	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
k141_539_1	177437.HRM2_31160	4.58e-81	254.0	COG2269@1|root,COG2269@2|Bacteria,1MU97@1224|Proteobacteria,42MAN@68525|delta/epsilon subdivisions,2WJBB@28221|Deltaproteobacteria,2MI3I@213118|Desulfobacterales	28221|Deltaproteobacteria	J	class II (D K and N)	genX	-	-	ko:K04568	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	tRNA-synt_2
k141_3548_1	879243.Poras_0201	5.04e-53	187.0	COG2265@1|root,COG2265@2|Bacteria,4NFP1@976|Bacteroidetes,2FNRC@200643|Bacteroidia,22X3X@171551|Porphyromonadaceae	976|Bacteroidetes	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	rumA	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TRAM,tRNA_U5-meth_tr
k141_1219_1	675806.VII_003363	1.84e-63	202.0	COG3137@1|root,COG3137@2|Bacteria,1N9KB@1224|Proteobacteria,1THEB@1236|Gammaproteobacteria,1XUUB@135623|Vibrionales	135623|Vibrionales	M	salt-induced outer membrane protein	VP2736	-	-	ko:K07283	-	-	-	-	ko00000	-	-	-	DUF481
k141_1219_2	243277.VC_0371	1.01e-305	837.0	COG0305@1|root,COG0305@2|Bacteria,1MUG9@1224|Proteobacteria,1RPM2@1236|Gammaproteobacteria,1XTT6@135623|Vibrionales	135623|Vibrionales	L	it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins	dnaB	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
k141_1219_3	1517681.HW45_26875	1.41e-71	218.0	COG0432@1|root,COG0432@2|Bacteria,1RH13@1224|Proteobacteria,1S3VP@1236|Gammaproteobacteria,1XWZM@135623|Vibrionales	135623|Vibrionales	S	Uncharacterised protein family UPF0047	-	-	-	-	-	-	-	-	-	-	-	-	UPF0047
k141_2828_1	526222.Desal_2559	3.08e-43	159.0	COG3864@1|root,COG3864@2|Bacteria,1MY13@1224|Proteobacteria,42QJ2@68525|delta/epsilon subdivisions,2WM78@28221|Deltaproteobacteria,2M8CT@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	VWA-like domain (DUF2201)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2201,DUF2201_N
k141_2828_2	1121441.AUCX01000012_gene3264	1.27e-67	216.0	COG0714@1|root,COG0714@2|Bacteria,1PHW4@1224|Proteobacteria,42QA8@68525|delta/epsilon subdivisions,2WJBW@28221|Deltaproteobacteria,2M8NS@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	PFAM ATPase associated with various cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	AAA_3,AAA_5
k141_3213_2	1216007.AOPM01000025_gene3282	2.78e-43	142.0	COG0361@1|root,COG0361@2|Bacteria,1MZFU@1224|Proteobacteria,1S8WZ@1236|Gammaproteobacteria,2Q31E@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
k141_3213_3	675814.VIC_004619	1.59e-114	333.0	COG2935@1|root,COG2935@2|Bacteria,1MW62@1224|Proteobacteria,1RYD7@1236|Gammaproteobacteria,1XSUB@135623|Vibrionales	135623|Vibrionales	O	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate	ate	GO:0003674,GO:0003824,GO:0004057,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006508,GO:0006511,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016598,GO:0016740,GO:0016746,GO:0016755,GO:0019538,GO:0019941,GO:0030163,GO:0036211,GO:0043170,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044464,GO:0051603,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575	2.3.2.29	ko:K21420	-	-	R11547,R11548	RC00064	ko00000,ko01000	-	-	-	ATE_C,ATE_N
k141_3213_4	617140.AJZE01000124_gene2650	1.71e-116	339.0	COG2360@1|root,COG2360@2|Bacteria,1R9W8@1224|Proteobacteria,1S1ZB@1236|Gammaproteobacteria,1XU2W@135623|Vibrionales	135623|Vibrionales	O	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine	aat	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008914,GO:0016740,GO:0016746,GO:0016755,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0071704,GO:0140096,GO:1901564	2.3.2.6	ko:K00684	-	-	R03813,R11443,R11444	RC00055,RC00064	ko00000,ko01000	-	-	-	Leu_Phe_trans
k141_540_1	555778.Hneap_1980	1.59e-32	135.0	COG0507@1|root,COG0507@2|Bacteria,1MW43@1224|Proteobacteria,1RPA0@1236|Gammaproteobacteria,1WVVS@135613|Chromatiales	135613|Chromatiales	L	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD	recD	-	3.1.11.5	ko:K03581	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AAA_30,UvrD_C_2
k141_541_1	1232437.KL662015_gene1247	6.1e-53	187.0	COG2203@1|root,COG2204@1|root,COG3437@1|root,COG4191@1|root,COG2203@2|Bacteria,COG2204@2|Bacteria,COG3437@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MC4@68525|delta/epsilon subdivisions,2WIZU@28221|Deltaproteobacteria,2MJ2F@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	ABC_sub_bind,GAF_2,HATPase_c,HisKA,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg,sCache_2
k141_234_1	765914.ThisiDRAFT_2695	2.77e-48	167.0	28JZ9@1|root,2Z9PC@2|Bacteria,1R7GE@1224|Proteobacteria,1S7TF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_234_2	1265505.ATUG01000002_gene1074	3.19e-120	374.0	COG0840@1|root,COG2703@1|root,COG0840@2|Bacteria,COG2703@2|Bacteria,1RBB1@1224|Proteobacteria,42RNA@68525|delta/epsilon subdivisions,2WNGN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	NPT	Hemerythrin HHE cation binding domain	-	-	-	ko:K03406,ko:K07216	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	Hemerythrin,MCPsignal,PilJ
k141_234_3	1265505.ATUG01000001_gene4094	2.78e-159	464.0	COG2304@1|root,COG2304@2|Bacteria,1MUTS@1224|Proteobacteria,42R8X@68525|delta/epsilon subdivisions,2WN6U@28221|Deltaproteobacteria,2MKTC@213118|Desulfobacterales	28221|Deltaproteobacteria	S	von Willebrand factor type A domain	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA
k141_234_4	1121396.KB893090_gene201	7.08e-72	241.0	COG5002@1|root,COG5002@2|Bacteria,1QXTS@1224|Proteobacteria,42QK0@68525|delta/epsilon subdivisions,2WJKM@28221|Deltaproteobacteria,2MKJ9@213118|Desulfobacterales	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
k141_4921_3	945550.VISI1226_21704	8.72e-84	250.0	COG2606@1|root,COG2606@2|Bacteria,1RGX5@1224|Proteobacteria,1S6S0@1236|Gammaproteobacteria,1XX0H@135623|Vibrionales	135623|Vibrionales	S	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily	ybaK	-	-	ko:K03976	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA_edit
k141_2613_1	1121324.CLIT_15c00080	2.76e-190	538.0	COG1979@1|root,COG1979@2|Bacteria,1TPS3@1239|Firmicutes,248DW@186801|Clostridia,25SRH@186804|Peptostreptococcaceae	186801|Clostridia	C	Iron-containing alcohol dehydrogenase	yqhD	-	-	ko:K08325,ko:K19955	ko00640,map00640	-	R02528	RC00739	ko00000,ko00001,ko01000	-	-	-	Fe-ADH
k141_936_2	349521.HCH_00410	4.39e-10	66.6	COG0834@1|root,COG0834@2|Bacteria,1RDBZ@1224|Proteobacteria,1S5AT@1236|Gammaproteobacteria,1XJWI@135619|Oceanospirillales	135619|Oceanospirillales	ET	ABC-type amino acid transport signal transduction systems, periplasmic component domain	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
k141_659_2	1304885.AUEY01000003_gene519	2.14e-63	196.0	COG0745@1|root,COG0745@2|Bacteria,1RDNP@1224|Proteobacteria,42RF8@68525|delta/epsilon subdivisions,2WNSP@28221|Deltaproteobacteria,2MJVR@213118|Desulfobacterales	28221|Deltaproteobacteria	T	cheY-homologous receiver domain	cheY	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
k141_659_3	1304885.AUEY01000002_gene416	1.73e-228	640.0	COG0017@1|root,COG0017@2|Bacteria,1MWFV@1224|Proteobacteria,42MJX@68525|delta/epsilon subdivisions,2WJDM@28221|Deltaproteobacteria,2MIBQ@213118|Desulfobacterales	28221|Deltaproteobacteria	J	class II (D K and N)	asnS	-	6.1.1.22	ko:K01893	ko00970,map00970	M00359,M00360	R03648	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
k141_4057_2	1089546.AQUI01000002_gene1249	4.43e-09	58.5	COG1925@1|root,COG3412@1|root,COG1925@2|Bacteria,COG3412@2|Bacteria,2IHRN@201174|Actinobacteria,408AP@622450|Actinopolysporales	201174|Actinobacteria	G	PTS system fructose IIA component	dhaM	-	2.7.1.121	ko:K05881	ko00561,map00561	-	R01012	RC00015,RC00017	ko00000,ko00001,ko01000,ko02000	-	-	-	EIIA-man,PTS-HPr
k141_4057_3	985867.AEWF01000008_gene1036	1.01e-18	80.5	COG0776@1|root,COG0776@2|Bacteria,1MZ5B@1224|Proteobacteria,2UC5G@28211|Alphaproteobacteria,47GIB@766|Rickettsiales	766|Rickettsiales	L	bacterial (prokaryotic) histone like domain	-	-	-	-	-	-	-	-	-	-	-	-	Bac_DNA_binding
k141_4057_4	323259.Mhun_1036	1.37e-19	85.5	COG1830@1|root,arCOG04044@2157|Archaea,2XTBQ@28890|Euryarchaeota,2N93C@224756|Methanomicrobia	224756|Methanomicrobia	E	Catalyzes a transaldol reaction between 6-deoxy-5- ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2- amino-3,7-dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids	-	-	2.2.1.10,4.1.2.13	ko:K16306	ko00010,ko00030,ko00051,ko00400,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00400,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001	R01068,R01070,R02568,R08568	RC00438,RC00439,RC00721,RC02301	ko00000,ko00001,ko00002,ko01000	-	-	-	DeoC
k141_2953_1	1348635.BBJY01000028_gene2081	8.7e-156	458.0	COG0006@1|root,COG0006@2|Bacteria,1MUZS@1224|Proteobacteria,1RPQD@1236|Gammaproteobacteria,1XST4@135623|Vibrionales	135623|Vibrionales	E	COG0006 Xaa-Pro aminopeptidase	ampP	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Creatinase_N,Creatinase_N_2,Peptidase_M24,Peptidase_M24_C
k141_2953_2	345073.VC395_0110	2.06e-47	153.0	2AWB4@1|root,31N6T@2|Bacteria,1QJY2@1224|Proteobacteria,1TI09@1236|Gammaproteobacteria,1XY2K@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_2953_3	55601.VANGNB10_cI2678	2.4e-95	279.0	COG1522@1|root,COG1522@2|Bacteria,1MWPX@1224|Proteobacteria,1RRPA@1236|Gammaproteobacteria,1XSDD@135623|Vibrionales	135623|Vibrionales	K	COG1522 Transcriptional regulators	asnC	-	-	ko:K03718	-	-	-	-	ko00000,ko03000	-	-	-	AsnC_trans_reg,HTH_AsnC-type
k141_2953_4	1051646.VITU9109_19667	3.61e-126	365.0	COG0742@1|root,COG0742@2|Bacteria,1MX8Z@1224|Proteobacteria,1RMIB@1236|Gammaproteobacteria,1XTAA@135623|Vibrionales	135623|Vibrionales	J	Specifically methylates the guanosine in position 1516 of 16S rRNA	rsmJ	-	2.1.1.242	ko:K15984	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SAM_MT
k141_2953_5	243277.VC_0075	9.41e-146	417.0	COG0697@1|root,COG0697@2|Bacteria,1MWMC@1224|Proteobacteria,1RQST@1236|Gammaproteobacteria,1XTFF@135623|Vibrionales	135623|Vibrionales	EG	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily	yigM	-	-	-	-	-	-	-	-	-	-	-	EamA
k141_2953_6	29495.EA26_01205	1.58e-71	218.0	COG0589@1|root,COG0589@2|Bacteria,1MV6Y@1224|Proteobacteria,1RQQ7@1236|Gammaproteobacteria,1XWVC@135623|Vibrionales	135623|Vibrionales	T	COG0589 Universal stress protein UspA and related nucleotide-binding proteins	uspA	-	-	ko:K06149	-	-	-	-	ko00000	-	-	-	Usp
k141_2953_7	1348635.BBJY01000028_gene2072	2.47e-105	306.0	COG1528@1|root,COG1528@2|Bacteria,1R9ZC@1224|Proteobacteria,1RYVB@1236|Gammaproteobacteria,1XTQA@135623|Vibrionales	135623|Vibrionales	P	Iron-storage protein	ftnA	-	1.16.3.2	ko:K02217	-	-	-	-	ko00000,ko01000	-	-	-	Ferritin
k141_2953_8	243277.VC_0079	1.19e-50	162.0	291H9@1|root,2ZP3V@2|Bacteria,1RDHD@1224|Proteobacteria,1S3P8@1236|Gammaproteobacteria,1XXMB@135623|Vibrionales	135623|Vibrionales	S	Universal stress protein B homolog	uspB	-	-	ko:K06144	-	-	-	-	ko00000,ko02000	9.B.4.1.1	-	-	UspB
k141_2953_9	1348635.BBJY01000028_gene2070	1.79e-221	618.0	COG2081@1|root,COG2081@2|Bacteria,1MUGC@1224|Proteobacteria,1RNCW@1236|Gammaproteobacteria,1XSRR@135623|Vibrionales	135623|Vibrionales	S	HI0933-like protein	yhiN	-	-	ko:K07007	-	-	-	-	ko00000	-	-	-	HI0933_like
k141_2953_10	223926.28805073	3.83e-194	544.0	COG0628@1|root,COG0628@2|Bacteria,1MXXU@1224|Proteobacteria,1RQCM@1236|Gammaproteobacteria,1XV4M@135623|Vibrionales	135623|Vibrionales	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
k141_2953_12	223926.28805071	8.41e-71	218.0	2B56A@1|root,31Y06@2|Bacteria,1QK8J@1224|Proteobacteria,1TIC1@1236|Gammaproteobacteria,1XYUH@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_2953_13	223926.28805070	3.76e-38	130.0	2CHJ0@1|root,33FNQ@2|Bacteria,1NNVV@1224|Proteobacteria,1SGKA@1236|Gammaproteobacteria,1XZ9I@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_2953_14	223926.28805069	1.43e-68	210.0	2DY9M@1|root,32V50@2|Bacteria,1QKPG@1224|Proteobacteria,1TITU@1236|Gammaproteobacteria,1XZN7@135623|Vibrionales	135623|Vibrionales	S	Domain of unknown function (DUF2383)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2383
k141_2953_15	223926.28805068	6.87e-64	197.0	29R0M@1|root,30C1R@2|Bacteria,1QMN8@1224|Proteobacteria,1TJXS@1236|Gammaproteobacteria,1Y1TV@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_2953_16	223926.28805067	0.0	906.0	COG1597@1|root,COG2453@1|root,COG1597@2|Bacteria,COG2453@2|Bacteria,1QSUD@1224|Proteobacteria,1RQAC@1236|Gammaproteobacteria,1XVX5@135623|Vibrionales	135623|Vibrionales	IT	Diacylglycerol kinase catalytic domain (presumed)	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat,DSPc
k141_2953_17	223926.28805066	5.8e-84	249.0	COG5592@1|root,COG5592@2|Bacteria,1RGUY@1224|Proteobacteria,1S5V6@1236|Gammaproteobacteria,1Y0TG@135623|Vibrionales	135623|Vibrionales	S	Hemerythrin HHE cation binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin
k141_2953_19	223926.28805063	4.3e-103	301.0	COG2823@1|root,COG2823@2|Bacteria,1PCIJ@1224|Proteobacteria,1RRGP@1236|Gammaproteobacteria,1XYNI@135623|Vibrionales	135623|Vibrionales	S	BON domain	-	-	-	-	-	-	-	-	-	-	-	-	BON
k141_2953_20	223926.28805062	4.54e-301	823.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RRR1@1236|Gammaproteobacteria,1XV34@135623|Vibrionales	135623|Vibrionales	K	Bacterial regulatory protein, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Sigma54_activat
k141_2953_21	1408424.JHYI01000002_gene4131	3.91e-113	330.0	COG0235@1|root,COG0235@2|Bacteria,1TPDV@1239|Firmicutes,4H9W0@91061|Bacilli,1ZDGI@1386|Bacillus	91061|Bacilli	G	COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases	araD	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0008742,GO:0009056,GO:0009058,GO:0009987,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019566,GO:0019568,GO:0019569,GO:0019572,GO:0019637,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046373,GO:0046872,GO:0046914,GO:0051167,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901159,GO:1901575,GO:1901576	5.1.3.4	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	M00550	R05850	RC01479	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldolase_II
k141_2953_23	1136163.M565_ctg4P380	2.53e-232	654.0	COG1322@1|root,COG1322@2|Bacteria,1MWHV@1224|Proteobacteria,1RMB8@1236|Gammaproteobacteria,1XV2P@135623|Vibrionales	135623|Vibrionales	S	dna recombination protein rmuc	rmuC	-	-	ko:K09760	-	-	-	-	ko00000	-	-	-	RmuC
k141_2953_25	1219076.N646_2285	2.8e-82	250.0	COG3165@1|root,COG3165@2|Bacteria,1R1CM@1224|Proteobacteria,1S745@1236|Gammaproteobacteria,1XUNJ@135623|Vibrionales	135623|Vibrionales	S	protein conserved in bacteria	-	-	-	ko:K03690	-	-	-	-	ko00000	-	-	-	SCP2
k141_2953_26	55601.VANGNB10_cI2656c	1.3e-90	281.0	COG0661@1|root,COG0661@2|Bacteria,1MU1Z@1224|Proteobacteria,1RNQM@1236|Gammaproteobacteria,1XSB2@135623|Vibrionales	135623|Vibrionales	H	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis	ubiB	GO:0003674,GO:0003824,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663	-	ko:K03688	-	-	-	-	ko00000	-	-	-	ABC1
k141_5092_1	497964.CfE428DRAFT_1965	1.48e-37	151.0	COG1413@1|root,COG1413@2|Bacteria,46WG8@74201|Verrucomicrobia	74201|Verrucomicrobia	C	lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_664_2	55601.VANGNB10_cII0854c	4.14e-65	207.0	COG3039@1|root,COG3039@2|Bacteria,1MXTN@1224|Proteobacteria,1RM94@1236|Gammaproteobacteria,1XVGA@135623|Vibrionales	135623|Vibrionales	L	User locus_tag	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_5
k141_664_4	55601.VANGNB10_cI0711	6.95e-85	297.0	COG1388@1|root,COG1388@2|Bacteria,1RC2P@1224|Proteobacteria,1T2A3@1236|Gammaproteobacteria,1XSVD@135623|Vibrionales	135623|Vibrionales	M	LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_664_5	33876.JNXY01000021_gene4695	7.25e-09	57.0	COG0789@1|root,COG0789@2|Bacteria,2IG7F@201174|Actinobacteria,4DM00@85008|Micromonosporales	201174|Actinobacteria	K	helix_turn_helix, mercury resistance	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
k141_664_6	258594.RPA4824	4.83e-27	103.0	2E1KM@1|root,32WY3@2|Bacteria,1N5IW@1224|Proteobacteria,2UDKY@28211|Alphaproteobacteria,3K55C@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Methylmuconolactone methyl-isomerase	-	-	-	-	-	-	-	-	-	-	-	-	EthD
k141_664_7	1348635.BBJY01000010_gene1386	3.08e-66	206.0	COG1247@1|root,COG1247@2|Bacteria,1RDHN@1224|Proteobacteria,1T03S@1236|Gammaproteobacteria,1Y2Y7@135623|Vibrionales	135623|Vibrionales	M	Phosphinothricin N-acetyltransferase	-	-	2.3.1.183	ko:K03823	ko00440,ko01130,map00440,map01130	-	R08871,R08938	RC00004,RC00064	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_4
k141_664_10	1038858.AXBA01000034_gene4893	1.57e-76	233.0	COG2258@1|root,COG2258@2|Bacteria,1RE9T@1224|Proteobacteria,2U740@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	PFAM MOSC domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	MOSC
k141_664_11	675815.VOA_000902	1.42e-178	501.0	COG0777@1|root,COG0777@2|Bacteria,1MW8G@1224|Proteobacteria,1RNDS@1236|Gammaproteobacteria,1XUXC@135623|Vibrionales	135623|Vibrionales	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA	-	-	2.1.3.15,6.4.1.2	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
k141_664_12	675815.VOA_000901	1.9e-184	516.0	COG0583@1|root,COG0583@2|Bacteria,1PUCV@1224|Proteobacteria,1RU5B@1236|Gammaproteobacteria,1XV11@135623|Vibrionales	135623|Vibrionales	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
k141_664_16	55601.VANGNB10_cI0928	5.04e-265	753.0	COG2812@1|root,COG2812@2|Bacteria,1MVCK@1224|Proteobacteria,1RMIA@1236|Gammaproteobacteria,1XV9Y@135623|Vibrionales	135623|Vibrionales	H	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3,DNA_pol3_tau_4,DNA_pol3_tau_5
k141_664_17	1280001.BAOA01000009_gene4112	1.6e-111	322.0	COG0503@1|root,COG0503@2|Bacteria,1MVZ6@1224|Proteobacteria,1S2N9@1236|Gammaproteobacteria,1XT0Q@135623|Vibrionales	135623|Vibrionales	F	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis	apt	GO:0003674,GO:0003824,GO:0003999,GO:0006139,GO:0006166,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0043094,GO:0043101,GO:0043174,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046128,GO:0046129,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.4.2.7	ko:K00759	ko00230,ko01100,map00230,map01100	-	R00190,R01229,R04378	RC00063	ko00000,ko00001,ko01000,ko04147	-	-	-	Pribosyltran
k141_664_18	223926.28807176	1.08e-133	393.0	COG2204@1|root,COG2204@2|Bacteria,1QUG8@1224|Proteobacteria,1T1Y0@1236|Gammaproteobacteria,1XT04@135623|Vibrionales	135623|Vibrionales	T	COG0784 FOG CheY-like receiver	rssB	-	-	-	-	-	-	-	-	-	-	-	Response_reg
k141_664_19	1348635.BBJY01000011_gene1211	4.26e-150	427.0	COG0583@1|root,COG0583@2|Bacteria,1R5BA@1224|Proteobacteria,1S4S1@1236|Gammaproteobacteria,1XT26@135623|Vibrionales	135623|Vibrionales	K	Transcriptional regulator	aphB	-	-	ko:K10918	ko05111,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_1,LysR_substrate
k141_664_20	1219077.VAZ01S_004_00360	1.13e-86	259.0	COG0778@1|root,COG0778@2|Bacteria,1PKUV@1224|Proteobacteria,1RNQG@1236|Gammaproteobacteria,1XU4Q@135623|Vibrionales	135623|Vibrionales	C	COG0778 Nitroreductase	ydjA	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
k141_664_21	1205908.AKXW01000162_gene2589	1.47e-259	739.0	COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,1RMZ8@1236|Gammaproteobacteria,1XV3W@135623|Vibrionales	135623|Vibrionales	I	Catalyzes the formation of a hydroxyacyl-CoA by addition of water on enoyl-CoA. Also exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities	fadJ	GO:0003674,GO:0003824,GO:0003857,GO:0004300,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0008692,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016491,GO:0016614,GO:0016616,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016854,GO:0016856,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575	1.1.1.35,4.2.1.17,5.1.2.3	ko:K01782	ko00071,ko00280,ko00281,ko00310,ko00362,ko00380,ko00410,ko00640,ko00650,ko00903,ko00930,ko01040,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00071,map00280,map00281,map00310,map00362,map00380,map00410,map00640,map00650,map00903,map00930,map01040,map01100,map01110,map01120,map01130,map01200,map01212	M00032,M00087	R01975,R03026,R03045,R03276,R04137,R04170,R04203,R04204,R04224,R04737,R04738,R04739,R04740,R04741,R04744,R04745,R04746,R04748,R04749,R05066,R05305,R06411,R06412,R06941,R06942,R07935,R07951,R08093,R08094	RC00029,RC00099,RC00117,RC00241,RC00525,RC00831,RC00834,RC00896,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	3HCDH,3HCDH_N,ECH_1
k141_664_22	1188252.AJYK01000089_gene656	6.71e-171	493.0	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,1RNGU@1236|Gammaproteobacteria,1XSJ5@135623|Vibrionales	135623|Vibrionales	I	Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed	fadI	GO:0003674,GO:0003824,GO:0003988,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016408,GO:0016740,GO:0016746,GO:0016747,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575	2.3.1.16	ko:K00632	ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212	M00087,M00113	R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955	ko00000,ko00001,ko00002,ko01000	-	-	-	Thiolase_C,Thiolase_N
k141_664_23	945550.VISI1226_17375	2.16e-59	189.0	COG0394@1|root,COG0394@2|Bacteria,1RH90@1224|Proteobacteria,1S5X6@1236|Gammaproteobacteria,1XXD3@135623|Vibrionales	135623|Vibrionales	T	Belongs to the low molecular weight phosphotyrosine protein phosphatase family	-	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
k141_664_25	1123236.KB899383_gene2653	4.42e-267	743.0	COG3534@1|root,COG3534@2|Bacteria,1PPWJ@1224|Proteobacteria,1RQ0J@1236|Gammaproteobacteria,465P4@72275|Alteromonadaceae	1236|Gammaproteobacteria	G	Alpha-L-arabinofuranosidase C-terminus	abfA	-	3.2.1.55	ko:K01209	ko00520,map00520	-	R01762	-	ko00000,ko00001,ko01000	-	GH51	-	Alpha-L-AF_C
k141_664_26	439375.Oant_0642	7.84e-20	92.0	COG0637@1|root,COG0637@2|Bacteria,1NSPA@1224|Proteobacteria,2U0W3@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
k141_664_27	314292.VAS14_18644	2.44e-39	141.0	COG3637@1|root,COG3637@2|Bacteria,1R3QN@1224|Proteobacteria,1RY3J@1236|Gammaproteobacteria,1XUQF@135623|Vibrionales	135623|Vibrionales	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	SO3905	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl
k141_664_28	1219065.VPR01S_05_01570	2.35e-155	439.0	COG2207@1|root,COG2207@2|Bacteria,1NETZ@1224|Proteobacteria,1RRXN@1236|Gammaproteobacteria,1XSYH@135623|Vibrionales	135623|Vibrionales	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
k141_664_29	675815.VOA_000998	4.01e-137	396.0	COG0697@1|root,COG0697@2|Bacteria,1MWSU@1224|Proteobacteria,1RSF8@1236|Gammaproteobacteria,1XTMR@135623|Vibrionales	135623|Vibrionales	EG	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily	-	-	-	-	-	-	-	-	-	-	-	-	EamA
k141_664_30	55601.VANGNB10_cII0923	3.85e-289	794.0	COG2271@1|root,COG2271@2|Bacteria,1MX4V@1224|Proteobacteria,1RMB3@1236|Gammaproteobacteria,1XSIZ@135623|Vibrionales	135623|Vibrionales	G	COG2271 Sugar phosphate permease	glpT	-	-	ko:K02445	-	-	-	-	ko00000,ko02000	2.A.1.4.3	-	-	MFS_1
k141_664_32	1238450.VIBNISOn1_560074	4.94e-152	431.0	COG0454@1|root,COG0456@2|Bacteria,1PW1F@1224|Proteobacteria,1THHD@1236|Gammaproteobacteria,1XVVJ@135623|Vibrionales	135623|Vibrionales	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_664_33	745411.B3C1_09323	3.74e-230	649.0	COG3866@1|root,COG3866@2|Bacteria,1QPFF@1224|Proteobacteria,1RQEM@1236|Gammaproteobacteria,1J9JE@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	G	Amb_all	pel1C	-	-	-	-	-	-	-	-	-	-	-	CBM_35,Pec_lyase_C,RicinB_lectin_2
k141_664_35	345073.VC395_1054	4.16e-112	325.0	COG2109@1|root,COG2109@2|Bacteria,1MUN6@1224|Proteobacteria,1RMH9@1236|Gammaproteobacteria,1XSJ7@135623|Vibrionales	135623|Vibrionales	H	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids	btuR	-	2.5.1.17	ko:K19221	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	Co_AT_N,CobA_CobO_BtuR
k141_664_36	1205908.AKXW01000095_gene2362	3.51e-94	286.0	COG1917@1|root,COG2207@1|root,COG1917@2|Bacteria,COG2207@2|Bacteria,1R3ZW@1224|Proteobacteria,1RZYX@1236|Gammaproteobacteria,1Y2JW@135623|Vibrionales	135623|Vibrionales	K	AraC-like ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
k141_664_37	1205908.AKXW01000095_gene2361	2.12e-93	278.0	COG1280@1|root,COG1280@2|Bacteria,1R3YJ@1224|Proteobacteria,1RSMF@1236|Gammaproteobacteria,1XWJ7@135623|Vibrionales	135623|Vibrionales	E	LysE type translocator	-	-	-	-	-	-	-	-	-	-	-	-	LysE
k141_664_38	1117315.AHCA01000011_gene1491	7.3e-160	468.0	COG3507@1|root,COG3507@2|Bacteria,1R50F@1224|Proteobacteria,1S1UF@1236|Gammaproteobacteria,2Q4C5@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	G	Ricin-type beta-trefoil	-	-	3.2.1.99	ko:K06113	-	-	-	-	ko00000,ko01000	-	GH43	-	Glyco_hydro_43,RicinB_lectin_2
k141_664_39	1123366.TH3_11420	5.98e-25	109.0	COG0834@1|root,COG0834@2|Bacteria	2|Bacteria	ET	amino acid transport	-	-	-	ko:K09996	ko02010,map02010	M00229	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3.3	-	-	SBP_bac_3
k141_664_40	345073.VC395_1053	3.25e-184	547.0	COG2982@1|root,COG2982@2|Bacteria,1NVUY@1224|Proteobacteria,1RPFM@1236|Gammaproteobacteria,1XSC9@135623|Vibrionales	135623|Vibrionales	M	protein involved in outer membrane biogenesis	asmA	-	-	ko:K07289	-	-	-	-	ko00000	-	-	-	AsmA
k141_664_42	1219065.VPR01S_02_01000	2.82e-163	467.0	COG0489@1|root,COG0489@2|Bacteria,1MU7R@1224|Proteobacteria,1RMJF@1236|Gammaproteobacteria,1XT74@135623|Vibrionales	135623|Vibrionales	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	mrp	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	ParA
k141_664_43	1348635.BBJY01000011_gene1224	0.0	1229.0	COG0073@1|root,COG0143@1|root,COG0073@2|Bacteria,COG0143@2|Bacteria,1MUBY@1224|Proteobacteria,1RMYM@1236|Gammaproteobacteria,1XUTN@135623|Vibrionales	135623|Vibrionales	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	GO:0003674,GO:0003824,GO:0004812,GO:0004825,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006431,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1g,tRNA_bind
k141_664_44	1348635.BBJY01000011_gene1225	8.46e-131	378.0	2AZSG@1|root,31S1S@2|Bacteria,1QJ9C@1224|Proteobacteria,1TH7Y@1236|Gammaproteobacteria,1XSAD@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_664_45	1190606.AJYG01000077_gene4040	1.21e-124	361.0	COG2820@1|root,COG2820@2|Bacteria,1P0EC@1224|Proteobacteria,1RN3N@1236|Gammaproteobacteria,1XSZE@135623|Vibrionales	135623|Vibrionales	F	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis	udp	-	2.4.2.3	ko:K00757	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01876,R02484,R08229	RC00063	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
k141_664_46	575788.VS_2085	7.94e-52	167.0	COG0517@1|root,COG0517@2|Bacteria,1N2XI@1224|Proteobacteria,1SEE5@1236|Gammaproteobacteria,1Y2PM@135623|Vibrionales	135623|Vibrionales	S	CBS domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS
k141_664_47	1348635.BBJY01000011_gene1228	1.52e-74	226.0	COG0314@1|root,COG0314@2|Bacteria,1RGUX@1224|Proteobacteria,1S5YH@1236|Gammaproteobacteria,1XX2Y@135623|Vibrionales	135623|Vibrionales	H	Molybdopterin converting factor, large subunit	moaE	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006732,GO:0006753,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009144,GO:0009150,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0016740,GO:0016782,GO:0016783,GO:0018130,GO:0019538,GO:0019637,GO:0019693,GO:0019720,GO:0030366,GO:0032324,GO:0034641,GO:0042278,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046039,GO:0046128,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657	2.8.1.12	ko:K03635	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09395	RC02507	ko00000,ko00001,ko01000	-	-	-	MoaE
k141_664_48	1298865.H978DRAFT_1691	1.35e-17	77.8	COG1977@1|root,COG1977@2|Bacteria	2|Bacteria	H	Mo-molybdopterin cofactor metabolic process	moaD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0071704,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.7.77,2.8.1.12	ko:K03636,ko:K03752,ko:K21142	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09395,R11581	RC02507	ko00000,ko00001,ko01000	-	-	iE2348C_1286.E2348C_0736,iEC55989_1330.EC55989_0827,iG2583_1286.G2583_1012,iLF82_1304.LF82_1368,iNRG857_1313.NRG857_03495,iSFV_1184.SFV_0767,iSF_1195.SF0734,iSFxv_1172.SFxv_0800,iSSON_1240.SSON_0763,iS_1188.S0775	ThiS
k141_664_49	754436.JCM19237_1515	7.38e-85	253.0	COG0315@1|root,COG0315@2|Bacteria,1RCYZ@1224|Proteobacteria,1S3ST@1236|Gammaproteobacteria,1XURA@135623|Vibrionales	135623|Vibrionales	H	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)	moaC	GO:0003674,GO:0003824,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0071704,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.6.1.17	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R11372	RC03425	ko00000,ko00001,ko01000	-	-	-	MoaC
k141_664_50	675813.VIB_000888	2.21e-101	295.0	COG0521@1|root,COG0521@2|Bacteria,1R9W2@1224|Proteobacteria,1S21E@1236|Gammaproteobacteria,1XTIY@135623|Vibrionales	135623|Vibrionales	H	May be involved in the biosynthesis of molybdopterin	moaB	-	2.7.7.75	ko:K03638	ko00790,ko01100,map00790,map01100	-	R09726	RC00002	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth
k141_664_51	672.VV93_v1c11170	2.07e-173	491.0	COG2896@1|root,COG2896@2|Bacteria,1MW3W@1224|Proteobacteria,1RR68@1236|Gammaproteobacteria,1XSSR@135623|Vibrionales	135623|Vibrionales	H	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate	moaA	GO:0003674,GO:0003824,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0071704,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.99.22	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394	RC03420	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Mob_synth_C,Radical_SAM
k141_664_52	29495.EA26_16355	7.95e-124	362.0	COG0391@1|root,COG0391@2|Bacteria,1NW3K@1224|Proteobacteria,1RQP9@1236|Gammaproteobacteria,1XUN3@135623|Vibrionales	135623|Vibrionales	S	Required for morphogenesis under gluconeogenic growth conditions	ybhK	-	-	-	-	-	-	-	-	-	-	-	UPF0052
k141_664_53	345073.VC395_1036	6.04e-28	105.0	COG2198@1|root,COG2198@2|Bacteria,1NH5B@1224|Proteobacteria,1SGR8@1236|Gammaproteobacteria,1XYAG@135623|Vibrionales	135623|Vibrionales	T	Phosphorelay protein which receives a sensory signal from a sensor kinase and transmit it to LuxO. At low cell density, a phosphoryl group is transferred from the sensor kinase, probably on His-56 and this phosphoryl group is further transferred to LuxO	luxU	GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008218,GO:0009372,GO:0009987,GO:0023052,GO:0044237,GO:0044764,GO:0050789,GO:0050794,GO:0050896,GO:0051704,GO:0051716,GO:0065007	-	ko:K10911	ko02020,ko02024,ko05111,map02020,map02024,map05111	M00513	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Hpt
k141_664_54	674977.VMC_37330	1.18e-269	751.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria,1XTGI@135623|Vibrionales	135623|Vibrionales	T	COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains	luxO	GO:0000156,GO:0000160,GO:0003674,GO:0003700,GO:0006355,GO:0007154,GO:0007165,GO:0008150,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0023052,GO:0031323,GO:0031326,GO:0035556,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0051716,GO:0060089,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2001141	-	ko:K10912	ko02020,ko02024,ko05111,map02020,map02024,map05111	M00513	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
k141_664_55	945543.VIBR0546_21670	0.0	1108.0	COG0556@1|root,COG0556@2|Bacteria,1MUFK@1224|Proteobacteria,1RN6Z@1236|Gammaproteobacteria,1XV2Z@135623|Vibrionales	135623|Vibrionales	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
k141_664_56	1348635.BBJY01000011_gene1249	2.6e-118	340.0	COG4657@1|root,COG4657@2|Bacteria,1MU8X@1224|Proteobacteria,1RQDN@1236|Gammaproteobacteria,1XSIP@135623|Vibrionales	135623|Vibrionales	C	Part of a membrane complex involved in electron transport	rnfA	GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0055114	-	ko:K03617	-	-	-	-	ko00000	-	-	-	Rnf-Nqr
k141_664_57	55601.VANGNB10_cI0885c	1.87e-91	272.0	COG2878@1|root,COG2878@2|Bacteria,1MUWU@1224|Proteobacteria,1RNSJ@1236|Gammaproteobacteria,1XSHC@135623|Vibrionales	135623|Vibrionales	C	Part of a membrane complex involved in electron transport	rnfB	GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0055114	-	ko:K03616	-	-	-	-	ko00000	-	-	-	FeS,Fer4_21
k141_664_58	1280001.BAOA01000020_gene365	1.75e-230	672.0	COG4656@1|root,COG4656@2|Bacteria,1QTUI@1224|Proteobacteria,1RMIM@1236|Gammaproteobacteria,1XTPN@135623|Vibrionales	135623|Vibrionales	C	Part of a membrane complex involved in electron transport	rnfC	GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0055114	-	ko:K03615	-	-	-	-	ko00000	-	-	-	Complex1_51K,Fer4,Fer4_10,Fer4_7,RnfC_N,SLBB
k141_664_59	55601.VANGNB10_cI0883c	2.44e-177	502.0	COG4658@1|root,COG4658@2|Bacteria,1MVY6@1224|Proteobacteria,1RMEU@1236|Gammaproteobacteria,1XSQB@135623|Vibrionales	135623|Vibrionales	C	Part of a membrane complex involved in electron transport	rnfD	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0044464,GO:0055114,GO:0071944	-	ko:K03614	-	-	-	-	ko00000	-	-	-	NQR2_RnfD_RnfE
k141_664_60	796620.VIBC2010_06359	2.38e-87	263.0	COG4659@1|root,COG4659@2|Bacteria,1RDEP@1224|Proteobacteria,1RPAD@1236|Gammaproteobacteria,1XU3Z@135623|Vibrionales	135623|Vibrionales	C	Part of a membrane complex involved in electron transport	rnfG	GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0055114	-	ko:K03612	-	-	-	-	ko00000	-	-	-	FMN_bind
k141_664_61	29495.EA26_16425	5.75e-112	327.0	COG4660@1|root,COG4660@2|Bacteria,1MW6N@1224|Proteobacteria,1RMEH@1236|Gammaproteobacteria,1XT8E@135623|Vibrionales	135623|Vibrionales	C	Part of a membrane complex involved in electron transport	rnfE	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0044464,GO:0055114,GO:0071944	-	ko:K03613	-	-	-	-	ko00000	-	-	-	Rnf-Nqr
k141_664_62	675813.VIB_001689	8.08e-125	358.0	COG0177@1|root,COG0177@2|Bacteria,1MUYQ@1224|Proteobacteria,1RMHU@1236|Gammaproteobacteria,1XTIS@135623|Vibrionales	135623|Vibrionales	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD
k141_664_63	675813.VIB_001690	1.34e-82	245.0	COG0346@1|root,COG0346@2|Bacteria,1RCYX@1224|Proteobacteria,1S1Z9@1236|Gammaproteobacteria,1XX01@135623|Vibrionales	135623|Vibrionales	E	Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione	gloA	GO:0003674,GO:0003824,GO:0004462,GO:0006518,GO:0006575,GO:0006749,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016846,GO:0034641,GO:0043603,GO:0044237,GO:0051186,GO:0071704,GO:1901564	4.4.1.5	ko:K01759	ko00620,map00620	-	R02530	RC00004,RC00740	ko00000,ko00001,ko01000	-	-	-	Glyoxalase
k141_664_64	675815.VOA_000632	5.63e-151	431.0	COG2885@1|root,COG2885@2|Bacteria,1PGGZ@1224|Proteobacteria,1RNFU@1236|Gammaproteobacteria,1XUNB@135623|Vibrionales	135623|Vibrionales	N	flagellar protein MotY	motY	-	-	ko:K21218	ko02040,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	OmpA
k141_664_66	223926.28807108	2.36e-240	669.0	COG2056@1|root,COG2056@2|Bacteria,1N8U2@1224|Proteobacteria,1RRW5@1236|Gammaproteobacteria,1XSSP@135623|Vibrionales	135623|Vibrionales	S	Na+-H+ antiporter family	-	-	-	ko:K07084	-	-	-	-	ko00000,ko02000	2.A.8.1.12	-	-	Na_H_antiport_2,Na_H_antiporter
k141_664_67	243277.VC_1004	0.0	882.0	COG0034@1|root,COG0034@2|Bacteria,1MU0V@1224|Proteobacteria,1RMYA@1236|Gammaproteobacteria,1XV4N@135623|Vibrionales	135623|Vibrionales	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_6,Pribosyltran
k141_664_68	55601.VANGNB10_cI0874	2.58e-76	231.0	COG1286@1|root,COG1286@2|Bacteria,1NF4G@1224|Proteobacteria,1RQ58@1236|Gammaproteobacteria,1XSSE@135623|Vibrionales	135623|Vibrionales	S	membrane protein, required for colicin V production	cvpA	-	-	ko:K03558	-	-	-	-	ko00000	-	-	-	Colicin_V
k141_664_69	345073.VC395_1017	1.61e-72	224.0	COG3147@1|root,COG3147@2|Bacteria,1NGE3@1224|Proteobacteria,1SCGC@1236|Gammaproteobacteria,1XVJ5@135623|Vibrionales	135623|Vibrionales	S	protein conserved in bacteria	dedD	-	-	ko:K03749	-	-	-	-	ko00000	-	-	-	SPOR
k141_1658_1	29495.EA26_08395	3.35e-64	205.0	COG2207@1|root,COG2207@2|Bacteria,1REAN@1224|Proteobacteria,1S3P2@1236|Gammaproteobacteria,1XTWJ@135623|Vibrionales	135623|Vibrionales	K	COG2207 AraC-type DNA-binding domain-containing proteins	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18,HTH_AraC
k141_1403_2	96561.Dole_2099	3.07e-35	124.0	2AB4Z@1|root,32TK9@2|Bacteria,1N53W@1224|Proteobacteria,42U1B@68525|delta/epsilon subdivisions,2X6XZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_398_1	1236541.BALL01000008_gene1393	3.4e-54	182.0	COG0286@1|root,COG0286@2|Bacteria,1MW3A@1224|Proteobacteria,1RRVF@1236|Gammaproteobacteria,2Q9PK@267890|Shewanellaceae	1236|Gammaproteobacteria	L	N-6 DNA methylase	hsdM	-	2.1.1.72	ko:K03427	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HsdM_N,N6_Mtase
k141_398_2	1354303.M917_1228	3.81e-21	92.8	COG4096@1|root,COG4096@2|Bacteria,1QTS7@1224|Proteobacteria,1RN63@1236|Gammaproteobacteria,3NMB2@468|Moraxellaceae	1236|Gammaproteobacteria	L	EcoEI R protein C-terminal	hsdR	-	3.1.21.3	ko:K01153	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	DUF4145,EcoEI_R_C,HSDR_N,HSDR_N_2,Helicase_C,ResIII
k141_399_1	675814.VIC_001197	1.03e-108	315.0	COG0454@1|root,COG0456@2|Bacteria,1R7GG@1224|Proteobacteria,1S2X0@1236|Gammaproteobacteria,1XVE6@135623|Vibrionales	135623|Vibrionales	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_7
k141_4788_3	675813.VIB_002911	2.71e-231	641.0	COG5433@1|root,COG5433@2|Bacteria,1MXB5@1224|Proteobacteria,1RSAV@1236|Gammaproteobacteria,1XZ6X@135623|Vibrionales	135623|Vibrionales	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_assoc
k141_4788_4	306264.CUP1190	4.77e-36	133.0	COG0500@1|root,COG2226@2|Bacteria,1N4YU@1224|Proteobacteria	1224|Proteobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
k141_4788_5	1280001.BAOA01000021_gene698	3.11e-152	437.0	COG2348@1|root,COG2348@2|Bacteria,1RG1R@1224|Proteobacteria,1TIZ2@1236|Gammaproteobacteria,1Y02I@135623|Vibrionales	135623|Vibrionales	V	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_6
k141_4788_6	1280001.BAOA01000021_gene699	4.53e-193	541.0	COG2089@1|root,COG2089@2|Bacteria,1MWG3@1224|Proteobacteria,1RPIG@1236|Gammaproteobacteria,1XSC4@135623|Vibrionales	135623|Vibrionales	M	NeuB family	-	-	2.5.1.56	ko:K01654	ko00520,ko01100,map00520,map01100	-	R01804,R04435	RC00159	ko00000,ko00001,ko01000	-	-	-	NeuB,SAF
k141_4788_7	1280001.BAOA01000021_gene700	3.42e-215	601.0	COG0381@1|root,COG0381@2|Bacteria,1MWZN@1224|Proteobacteria,1THG0@1236|Gammaproteobacteria,1XVI6@135623|Vibrionales	135623|Vibrionales	M	UDP-N-acetylglucosamine 2-epimerase	-	-	5.1.3.14	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	M00362	R00420	RC00290	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase_2
k141_4788_8	326297.Sama_2333	7.82e-116	345.0	COG0399@1|root,COG0399@2|Bacteria,1NDEK@1224|Proteobacteria,1SG0M@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	UDP-4-amino-4-deoxy-L-arabinose aminotransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_4788_9	1280001.BAOA01000021_gene704	9.38e-185	520.0	COG0517@1|root,COG1208@1|root,COG0517@2|Bacteria,COG1208@2|Bacteria,1MUYJ@1224|Proteobacteria,1RQPI@1236|Gammaproteobacteria,1XSMC@135623|Vibrionales	135623|Vibrionales	M	Nucleotidyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	CBS,NTP_transferase
k141_400_1	1304885.AUEY01000004_gene912	1.46e-131	384.0	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,42MSR@68525|delta/epsilon subdivisions,2WIXG@28221|Deltaproteobacteria,2MIJC@213118|Desulfobacterales	28221|Deltaproteobacteria	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
k141_3442_1	1190606.AJYG01000103_gene1166	1.11e-13	70.5	COG0438@1|root,COG0438@2|Bacteria,1MU9C@1224|Proteobacteria,1RTS0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Glycosyl transferases group 1	lpcC	-	-	ko:K12989	-	-	-	-	ko00000,ko01000,ko01003,ko01005	-	GT4	-	Glyco_transf_4,Glycos_transf_1
k141_3442_2	674977.VMC_14520	1.52e-213	591.0	COG0451@1|root,COG0451@2|Bacteria,1MVE4@1224|Proteobacteria,1RP2S@1236|Gammaproteobacteria,1XTH4@135623|Vibrionales	135623|Vibrionales	GM	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose	hldD	GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008712,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016853,GO:0016854,GO:0016857,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0046401,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509	5.1.3.20	ko:K03274	ko00540,ko01100,map00540,map01100	M00064	R05176	RC01291	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase
k141_3442_3	326297.Sama_2261	1.73e-39	140.0	COG0381@1|root,COG0381@2|Bacteria,1MWZN@1224|Proteobacteria,1RPNC@1236|Gammaproteobacteria,2QAMB@267890|Shewanellaceae	1236|Gammaproteobacteria	M	Belongs to the UDP-N-acetylglucosamine 2-epimerase family	wecB	GO:0000271,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0008150,GO:0008152,GO:0008761,GO:0009058,GO:0009059,GO:0009246,GO:0009987,GO:0016051,GO:0016853,GO:0016854,GO:0016857,GO:0033692,GO:0034637,GO:0034645,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046378,GO:0071704,GO:1901135,GO:1901137,GO:1901576	3.2.1.183,5.1.3.14	ko:K01791,ko:K08068	ko00520,ko01100,ko05111,map00520,map01100,map05111	M00362	R00420	RC00290	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	iECOK1_1307.ECOK1_4232,iECS88_1305.ECS88_4208,iECs_1301.ECs4719,iEcSMS35_1347.EcSMS35_4150,iG2583_1286.G2583_4580,iPC815.YPO3864,iSDY_1059.SDY_3962,iSSON_1240.SSON_3958,iUMN146_1321.UM146_19070,iZ_1308.Z5297	Epimerase_2
k141_4119_13	1219065.VPR01S_07_01040	2.77e-58	183.0	2AW5Q@1|root,31N0Q@2|Bacteria,1QJSF@1224|Proteobacteria,1THTS@1236|Gammaproteobacteria,1XXI7@135623|Vibrionales	135623|Vibrionales	S	Protein of unknown function (DUF3319)	VPA0887	-	-	-	-	-	-	-	-	-	-	-	DUF3319
k141_4119_14	1136163.M565_ctg5P0618	1.49e-81	257.0	COG4974@1|root,COG4974@2|Bacteria,1RK0K@1224|Proteobacteria,1RY57@1236|Gammaproteobacteria,1XTC1@135623|Vibrionales	135623|Vibrionales	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
k141_4119_15	675813.VIB_002180	2.22e-161	461.0	COG1181@1|root,COG1181@2|Bacteria,1MUTB@1224|Proteobacteria,1RMTM@1236|Gammaproteobacteria,1XUIJ@135623|Vibrionales	135623|Vibrionales	F	Belongs to the D-alanine--D-alanine ligase family	ddl	GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008716,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
k141_4119_16	1051646.VITU9109_18865	1.43e-70	219.0	COG3266@1|root,COG3266@2|Bacteria,1QJDK@1224|Proteobacteria,1THCR@1236|Gammaproteobacteria,1XU08@135623|Vibrionales	135623|Vibrionales	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	SPOR
k141_4119_17	675813.VIB_002184	1.97e-145	417.0	COG0583@1|root,COG0583@2|Bacteria,1MZTA@1224|Proteobacteria,1RN7R@1236|Gammaproteobacteria,1XSKB@135623|Vibrionales	135623|Vibrionales	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
k141_4119_18	55601.VANGNB10_cII0474c	1.58e-283	789.0	COG4533@1|root,COG4533@2|Bacteria,1N2NK@1224|Proteobacteria,1RP2Z@1236|Gammaproteobacteria,1XUBB@135623|Vibrionales	135623|Vibrionales	K	transport system periplasmic component	sgrR	-	-	ko:K11925	-	-	-	-	ko00000,ko03000	-	-	-	SBP_bac_5,SgrR_N
k141_4119_19	1219065.VPR01S_07_01150	9.23e-74	224.0	COG2050@1|root,COG2050@2|Bacteria,1RGVP@1224|Proteobacteria,1S5WY@1236|Gammaproteobacteria,1XWX9@135623|Vibrionales	135623|Vibrionales	Q	protein possibly involved in aromatic compounds catabolism	ydiI	-	-	-	-	-	-	-	-	-	-	-	4HBT
k141_4119_20	945543.VIBR0546_04052	1.54e-110	327.0	COG0501@1|root,COG0501@2|Bacteria,1MUNA@1224|Proteobacteria,1RMZ6@1236|Gammaproteobacteria,1XTEI@135623|Vibrionales	135623|Vibrionales	O	Zn-dependent protease with chaperone function	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
k141_4119_21	1348635.BBJY01000014_gene839	3.45e-116	334.0	COG2824@1|root,COG2824@2|Bacteria,1RGUU@1224|Proteobacteria,1S60W@1236|Gammaproteobacteria,1XVM9@135623|Vibrionales	135623|Vibrionales	P	Zn-ribbon-containing protein involved in phosphonate metabolism	phnA	-	-	ko:K06193	ko01120,map01120	-	-	-	ko00000	-	-	-	PhnA,PhnA_Zn_Ribbon
k141_4119_22	1219076.N646_3305	5.52e-40	132.0	COG4628@1|root,COG4628@2|Bacteria,1N7DG@1224|Proteobacteria,1SCBE@1236|Gammaproteobacteria,1XYE5@135623|Vibrionales	135623|Vibrionales	S	DNA-binding protein VF530	-	GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0097159,GO:1901363	-	-	-	-	-	-	-	-	-	-	VF530
k141_4119_23	1283284.AZUK01000001_gene506	4.09e-162	468.0	COG1940@1|root,COG1940@2|Bacteria,1NFM0@1224|Proteobacteria,1RNEA@1236|Gammaproteobacteria,1Y3YY@135624|Aeromonadales	135624|Aeromonadales	GK	ROK family	nagC	-	-	ko:K02565	-	-	-	-	ko00000,ko03000	-	-	-	ROK
k141_4119_24	1283284.AZUK01000001_gene505	1.35e-181	516.0	COG1820@1|root,COG1820@2|Bacteria,1MW8Y@1224|Proteobacteria,1RMRV@1236|Gammaproteobacteria,1Y3SZ@135624|Aeromonadales	135624|Aeromonadales	G	Belongs to the metallo-dependent hydrolases superfamily. NagA family	nagA	-	3.5.1.25	ko:K01443	ko00520,ko01130,map00520,map01130	-	R02059	RC00166,RC00300	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
k141_4119_25	595494.Tola_2136	1.6e-139	400.0	COG0363@1|root,COG0363@2|Bacteria,1MVEA@1224|Proteobacteria,1RQ2V@1236|Gammaproteobacteria,1Y3Z3@135624|Aeromonadales	135624|Aeromonadales	G	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion	nagB	-	3.5.99.6	ko:K02564	ko00520,ko01100,map00520,map01100	-	R00765	RC00163	ko00000,ko00001,ko01000	-	-	-	Glucosamine_iso
k141_4119_26	595494.Tola_2135	2.24e-266	740.0	COG1263@1|root,COG1264@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,1MY1V@1224|Proteobacteria,1RMYZ@1236|Gammaproteobacteria,1Y3SR@135624|Aeromonadales	135624|Aeromonadales	G	PTS system, N-acetylglucosamine-specific	nagE	-	2.7.1.193	ko:K02803,ko:K02804	ko00520,ko02060,map00520,map02060	M00267	R05199	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.1.1.15,4.A.1.1.2,4.A.1.1.5,4.A.1.1.7	-	-	PTS_EIIB,PTS_EIIC
k141_4119_27	1116375.VEJY3_20481	7.8e-232	649.0	COG1115@1|root,COG1115@2|Bacteria,1MUI3@1224|Proteobacteria,1RMNF@1236|Gammaproteobacteria,1XZXD@135623|Vibrionales	135623|Vibrionales	E	Sodium:alanine symporter family	-	-	-	ko:K03310	-	-	-	-	ko00000	2.A.25	-	-	Na_Ala_symp
k141_432_1	1304885.AUEY01000010_gene1694	5.8e-158	484.0	COG0449@1|root,COG0449@2|Bacteria,1MW4K@1224|Proteobacteria,42KZ7@68525|delta/epsilon subdivisions,2WJP6@28221|Deltaproteobacteria,2MIWZ@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	iAF987.Gmet_1487	GATase_6,SIS
k141_127_2	1116375.VEJY3_21356	1.11e-243	672.0	COG0673@1|root,COG0673@2|Bacteria,1N0VK@1224|Proteobacteria,1RNF2@1236|Gammaproteobacteria,1XWSX@135623|Vibrionales	135623|Vibrionales	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
k141_127_3	1116375.VEJY3_21351	4.41e-81	246.0	COG2207@1|root,COG2207@2|Bacteria	2|Bacteria	K	Transcriptional regulator	-	-	-	ko:K21826	-	-	-	-	ko00000,ko03000	-	-	-	AraC_binding,HTH_18,HTH_AraC
k141_4121_1	1337936.IJ00_02425	2.9e-52	172.0	COG0317@1|root,COG0317@2|Bacteria,1GHMV@1117|Cyanobacteria,1HRXC@1161|Nostocales	1117|Cyanobacteria	KT	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	HD_4
k141_433_2	1202962.KB907164_gene3906	2.64e-83	268.0	COG1195@1|root,COG3593@1|root,COG1195@2|Bacteria,COG3593@2|Bacteria,1R5X9@1224|Proteobacteria,1RZQT@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_15
k141_1761_2	1219065.VPR01S_29_00410	0.0	1270.0	COG0480@1|root,COG0480@2|Bacteria,1MUCV@1224|Proteobacteria,1RNSZ@1236|Gammaproteobacteria,1XSMB@135623|Vibrionales	135623|Vibrionales	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA1	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
k141_1761_3	29495.EA26_19755	4.81e-96	281.0	COG0049@1|root,COG0049@2|Bacteria,1MXC8@1224|Proteobacteria,1RN77@1236|Gammaproteobacteria,1XT47@135623|Vibrionales	135623|Vibrionales	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA	rpsG	GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02992	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S7
k141_1761_4	870967.VIS19158_19001	1.41e-84	249.0	COG0048@1|root,COG0048@2|Bacteria,1RCWY@1224|Proteobacteria,1S3WB@1236|Gammaproteobacteria,1XWXF@135623|Vibrionales	135623|Vibrionales	J	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit	rpsL	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02950	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosom_S12_S23
k141_1761_6	1115515.EV102420_16_00050	7.52e-24	95.5	COG2923@1|root,COG2923@2|Bacteria,1N8RV@1224|Proteobacteria,1SD0S@1236|Gammaproteobacteria,3XPSC@561|Escherichia	1236|Gammaproteobacteria	J	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions	tusC	GO:0002097,GO:0002098,GO:0002143,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1902494,GO:1990228,GO:1990234	-	ko:K07236	ko04122,map04122	-	-	-	ko00000,ko00001,ko03016	-	-	-	DrsE
k141_1761_7	1348635.BBJY01000031_gene2111	4.68e-60	188.0	COG1553@1|root,COG1553@2|Bacteria,1N021@1224|Proteobacteria,1S99J@1236|Gammaproteobacteria,1XXDD@135623|Vibrionales	135623|Vibrionales	P	conserved protein involved in intracellular sulfur reduction	tusD	-	-	ko:K07235	ko04122,map04122	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	DrsE
k141_1761_9	1219065.VPR01S_29_00340	1.01e-104	312.0	COG0545@1|root,COG0545@2|Bacteria,1RDA1@1224|Proteobacteria,1RRKU@1236|Gammaproteobacteria,1XSY6@135623|Vibrionales	135623|Vibrionales	M	COG0545 FKBP-type peptidyl-prolyl cis-trans isomerases 1	fkpA	-	5.2.1.8	ko:K03772	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C,FKBP_N
k141_1761_10	29495.EA26_19790	1.75e-113	338.0	COG2319@1|root,COG2319@2|Bacteria,1PDT0@1224|Proteobacteria,1RV85@1236|Gammaproteobacteria,1XTYR@135623|Vibrionales	135623|Vibrionales	S	COG2319 FOG WD40 repeat	-	-	-	-	-	-	-	-	-	-	-	-	WD40
k141_1761_11	1219065.VPR01S_29_00320	6.36e-30	107.0	COG2900@1|root,COG2900@2|Bacteria,1NGFM@1224|Proteobacteria,1SGAM@1236|Gammaproteobacteria,1XYDM@135623|Vibrionales	135623|Vibrionales	S	Belongs to the SlyX family	slyX	-	-	ko:K03745	-	-	-	-	ko00000	-	-	-	SlyX
k141_1761_12	1344012.ATMI01000040_gene673	2.07e-16	72.4	COG3242@1|root,COG3242@2|Bacteria,1PU4J@1224|Proteobacteria,1RWCV@1236|Gammaproteobacteria,4BVCA@82986|Tatumella	1236|Gammaproteobacteria	S	Uncharacterized protein conserved in bacteria (DUF2065)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2065
k141_1761_14	29495.EA26_19940	3.86e-200	564.0	COG0330@1|root,COG0330@2|Bacteria,1MUM2@1224|Proteobacteria,1RMUG@1236|Gammaproteobacteria,1XU48@135623|Vibrionales	135623|Vibrionales	O	HflC and HflK could encode or regulate a protease	hflK	GO:0003674,GO:0003824,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:0140096,GO:1901564	-	ko:K04088	-	M00742	-	-	ko00000,ko00002,ko01000	-	-	-	Band_7,HflK_N
k141_1761_15	1348635.BBJY01000031_gene2103	5.01e-255	706.0	COG2262@1|root,COG2262@2|Bacteria,1MUA0@1224|Proteobacteria,1RN7V@1236|Gammaproteobacteria,1XUG9@135623|Vibrionales	135623|Vibrionales	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
k141_1761_16	948565.AFFP02000008_gene1702	6.92e-42	139.0	COG1923@1|root,COG1923@2|Bacteria,1MZM1@1224|Proteobacteria,1S8W0@1236|Gammaproteobacteria,1Y904@135625|Pasteurellales	135625|Pasteurellales	J	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs	hfq	-	-	ko:K03666	ko02024,ko03018,ko05111,map02024,map03018,map05111	-	-	-	ko00000,ko00001,ko03019,ko03036	-	-	-	Hfq
k141_1761_17	672.VV93_v1c28000	6.18e-185	518.0	COG0324@1|root,COG0324@2|Bacteria,1MUB2@1224|Proteobacteria,1RMDU@1236|Gammaproteobacteria,1XSXN@135623|Vibrionales	135623|Vibrionales	F	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
k141_1761_18	1348635.BBJY01000031_gene2100	1.32e-264	749.0	COG0323@1|root,COG0323@2|Bacteria,1MV61@1224|Proteobacteria,1RM89@1236|Gammaproteobacteria,1XTP3@135623|Vibrionales	135623|Vibrionales	L	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	mutL	GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391	-	ko:K03572	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	DNA_mis_repair,HATPase_c_3,MutL_C
k141_1761_19	1219065.VPR01S_29_00240	2.99e-266	746.0	COG0860@1|root,COG1388@1|root,COG0860@2|Bacteria,COG1388@2|Bacteria,1MUQK@1224|Proteobacteria,1RMP1@1236|Gammaproteobacteria,1XU2J@135623|Vibrionales	135623|Vibrionales	M	N-acetylmuramoyl-L-alanine amidase	amiB	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	AMIN,Amidase_3,LysM
k141_1761_20	1348635.BBJY01000031_gene2098	2.89e-89	263.0	COG0802@1|root,COG0802@2|Bacteria,1RGYU@1224|Proteobacteria,1S6IB@1236|Gammaproteobacteria,1XUDS@135623|Vibrionales	135623|Vibrionales	S	ATPase or kinase	yjeE	-	-	ko:K06925	-	-	-	-	ko00000,ko03016	-	-	-	TsaE
k141_1761_21	55601.VANGNB10_cI0225c	5.53e-205	574.0	COG1600@1|root,COG1600@2|Bacteria,1MV1H@1224|Proteobacteria,1RMD9@1236|Gammaproteobacteria,1XSXR@135623|Vibrionales	135623|Vibrionales	C	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)	queG	GO:0003674,GO:0003824,GO:0006091,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009055,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016491,GO:0018130,GO:0019438,GO:0022900,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0052693,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	1.17.99.6	ko:K18979	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF1730,Fer4_16
k141_1761_22	55601.VANGNB10_cI0224	1.72e-108	314.0	COG1949@1|root,COG1949@2|Bacteria,1R9WX@1224|Proteobacteria,1S217@1236|Gammaproteobacteria,1XSRQ@135623|Vibrionales	135623|Vibrionales	A	3'-to-5' exoribonuclease specific for small oligoribonucleotides	orn	GO:0000175,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0140098,GO:1901360,GO:1901361,GO:1901575	-	ko:K13288	ko03008,map03008	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	RNase_T
k141_1761_23	55601.VANGNB10_cI0223c	6.83e-198	555.0	COG1162@1|root,COG1162@2|Bacteria,1MUEF@1224|Proteobacteria,1RMMB@1236|Gammaproteobacteria,1XTBR@135623|Vibrionales	135623|Vibrionales	S	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit	rsgA	-	3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100	-	R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009	-	-	-	RsgA_GTPase
k141_1761_24	345073.VC395_0382	3.41e-155	441.0	COG0688@1|root,COG0688@2|Bacteria,1MVT4@1224|Proteobacteria,1RN1U@1236|Gammaproteobacteria,1XT0P@135623|Vibrionales	135623|Vibrionales	I	Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)	psd	GO:0003674,GO:0003824,GO:0004609,GO:0006629,GO:0006644,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0071704,GO:0090407,GO:1901576	4.1.1.65	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	M00093	R02055	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	PS_Dcarbxylase
k141_1761_25	945550.VISI1226_14477	8.41e-263	729.0	COG0471@1|root,COG0471@2|Bacteria,1R6QF@1224|Proteobacteria,1RQIG@1236|Gammaproteobacteria,1XTZX@135623|Vibrionales	135623|Vibrionales	P	COG0471 Di- and tricarboxylate transporters	-	-	-	ko:K14445	-	-	-	-	ko00000,ko02000	2.A.47.1	-	-	Na_sulph_symp
k141_1761_26	675806.VII_003395	0.0	885.0	COG0696@1|root,COG0696@2|Bacteria,1MUQ1@1224|Proteobacteria,1RMJE@1236|Gammaproteobacteria,1XTMH@135623|Vibrionales	135623|Vibrionales	G	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate	gpmI	GO:0003674,GO:0003824,GO:0004619,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576	5.4.2.12	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,Phosphodiest,iPGM_N
k141_1761_27	1219065.VPR01S_29_00140	4.81e-117	352.0	COG4942@1|root,COG4942@2|Bacteria,1MY3E@1224|Proteobacteria,1RPQP@1236|Gammaproteobacteria,1XSXQ@135623|Vibrionales	135623|Vibrionales	D	COG4942 Membrane-bound metallopeptidase	envC	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
k141_1761_28	617140.AJZE01000046_gene606	3.16e-210	587.0	COG0407@1|root,COG0407@2|Bacteria,1MUG1@1224|Proteobacteria,1RMDH@1236|Gammaproteobacteria,1XTP5@135623|Vibrionales	135623|Vibrionales	H	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III	hemE	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
k141_1761_29	1348635.BBJY01000030_gene2126	6.51e-144	411.0	COG2816@1|root,COG2816@2|Bacteria,1QGCX@1224|Proteobacteria,1RP0Y@1236|Gammaproteobacteria,1XV54@135623|Vibrionales	135623|Vibrionales	L	COG2816 NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding	nudC	GO:0003674,GO:0003824,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360	3.6.1.22	ko:K03426	ko00760,ko01100,ko04146,map00760,map01100,map04146	-	R00103,R03004,R11104	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX,zf-NADH-PPase
k141_1761_30	29495.EA26_20450	5.34e-67	208.0	COG3160@1|root,COG3160@2|Bacteria,1RHBB@1224|Proteobacteria,1S420@1236|Gammaproteobacteria,1XWY4@135623|Vibrionales	135623|Vibrionales	K	Belongs to the Rsd AlgQ family	rsd	-	-	ko:K07740	-	-	-	-	ko00000	-	-	-	Rsd_AlgQ
k141_1761_31	1348635.BBJY01000030_gene2124	0.0	2582.0	COG0086@1|root,COG0086@2|Bacteria,1MU3M@1224|Proteobacteria,1RPYH@1236|Gammaproteobacteria,1XTEN@135623|Vibrionales	135623|Vibrionales	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	GO:0000428,GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030880,GO:0032774,GO:0032991,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
k141_1761_33	1280001.BAOA01000261_gene2597	3.61e-50	162.0	COG0222@1|root,COG0222@2|Bacteria,1RGU4@1224|Proteobacteria,1S5V7@1236|Gammaproteobacteria,1XXAI@135623|Vibrionales	135623|Vibrionales	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation	rplL	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02935	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L12,Ribosomal_L12_N
k141_1761_34	945550.VISI1226_14542	5.92e-96	281.0	COG0244@1|root,COG0244@2|Bacteria,1RAN5@1224|Proteobacteria,1S286@1236|Gammaproteobacteria,1XTXN@135623|Vibrionales	135623|Vibrionales	J	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors	rplJ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02864	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L10
k141_1761_35	1219065.VPR01S_29_00040	1.77e-143	407.0	COG0081@1|root,COG0081@2|Bacteria,1MUE6@1224|Proteobacteria,1RMDW@1236|Gammaproteobacteria,1XSM0@135623|Vibrionales	135623|Vibrionales	J	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release	rplA	GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02863	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L1
k141_1761_36	575788.VS_2968	5.47e-86	255.0	COG0080@1|root,COG0080@2|Bacteria,1RA2M@1224|Proteobacteria,1S22R@1236|Gammaproteobacteria,1XSSH@135623|Vibrionales	135623|Vibrionales	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors	rplK	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02867	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L11,Ribosomal_L11_N
k141_1761_37	1238450.VIBNISOn1_950039	3.14e-125	357.0	COG0250@1|root,COG0250@2|Bacteria,1MU14@1224|Proteobacteria,1RMW0@1236|Gammaproteobacteria,1XTDF@135623|Vibrionales	135623|Vibrionales	K	Participates in transcription elongation, termination and antitermination	nusG	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006353,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031326,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2001141	-	ko:K02601	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KOW,NusG
k141_1761_38	617140.AJZE01000046_gene616	1.51e-51	166.0	COG0690@1|root,COG0690@2|Bacteria,1RDI9@1224|Proteobacteria,1S3PA@1236|Gammaproteobacteria,1XXD8@135623|Vibrionales	135623|Vibrionales	U	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation	secE	GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705	-	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecE
k141_1761_39	575788.VS_2972	6.57e-267	733.0	COG0050@1|root,COG0050@2|Bacteria,1MVC0@1224|Proteobacteria,1RMYX@1236|Gammaproteobacteria,1XSP1@135623|Vibrionales	135623|Vibrionales	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
k141_1761_40	1219065.VPR01S_26_00580	7.15e-177	498.0	COG1072@1|root,COG1072@2|Bacteria,1MV3M@1224|Proteobacteria,1RNXX@1236|Gammaproteobacteria,1XUCB@135623|Vibrionales	135623|Vibrionales	F	pantothenic acid kinase	coaA	GO:0003674,GO:0003824,GO:0004594,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.1.33	ko:K00867	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PRK
k141_1761_41	945543.VIBR0546_14647	2.33e-161	459.0	COG0340@1|root,COG1654@1|root,COG0340@2|Bacteria,COG1654@2|Bacteria,1MWCC@1224|Proteobacteria,1RNGC@1236|Gammaproteobacteria,1XUFE@135623|Vibrionales	135623|Vibrionales	H	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon	birA	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_C,BPL_LplA_LipB,HTH_11
k141_1761_42	1219065.VPR01S_04_01800	3.59e-149	431.0	COG0812@1|root,COG0812@2|Bacteria,1MXDH@1224|Proteobacteria,1RNXK@1236|Gammaproteobacteria,1XTDX@135623|Vibrionales	135623|Vibrionales	M	Cell wall formation	murB	GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008762,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0055114,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	-	FAD_binding_4,MurB_C
k141_1761_43	945543.VIBR0546_14657	5.06e-43	145.0	COG3153@1|root,COG3153@2|Bacteria,1QUGJ@1224|Proteobacteria,1T1YA@1236|Gammaproteobacteria,1XYFN@135623|Vibrionales	135623|Vibrionales	S	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_10,Acetyltransf_7
k141_1761_44	243277.VC_0315	3.61e-228	639.0	COG1502@1|root,COG1502@2|Bacteria,1MVPU@1224|Proteobacteria,1RN1V@1236|Gammaproteobacteria,1XT62@135623|Vibrionales	135623|Vibrionales	I	COG1502 Phosphatidylserine phosphatidylglycerophosphate cardiolipi n synthases and related enzymes	pssA	-	2.7.8.8	ko:K00998	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	M00093	R01800	RC00002,RC00017,RC02795	ko00000,ko00001,ko00002,ko01000	-	-	-	PLDc_2,Regulator_TrmB
k141_3497_2	1237149.C900_01573	1.47e-271	771.0	COG2183@1|root,COG2183@2|Bacteria,4NETD@976|Bacteroidetes,47MKQ@768503|Cytophagia	976|Bacteroidetes	K	TIGRFAM competence protein ComEA helix-hairpin-helix repeat region	yhgF	-	-	ko:K06959	-	-	-	-	ko00000	-	-	-	HHH_3,S1,Tex_N,Tex_YqgF
k141_2083_1	675814.VIC_002359	1.1e-39	139.0	COG2207@1|root,COG2207@2|Bacteria,1REAN@1224|Proteobacteria,1S3P2@1236|Gammaproteobacteria,1XTWJ@135623|Vibrionales	135623|Vibrionales	K	COG2207 AraC-type DNA-binding domain-containing proteins	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18,HTH_AraC
k141_2083_2	55601.VANGNB10_cII0992c	0.0	1604.0	COG0506@1|root,COG4230@1|root,COG0506@2|Bacteria,COG4230@2|Bacteria,1MV93@1224|Proteobacteria,1RN48@1236|Gammaproteobacteria,1XTWM@135623|Vibrionales	135623|Vibrionales	C	Oxidizes proline to glutamate for use as a carbon and nitrogen source	putA	-	1.2.1.88,1.5.5.2	ko:K13821	ko00250,ko00330,ko01100,ko01110,ko01130,map00250,map00330,map01100,map01110,map01130	-	R00245,R00707,R00708,R01253,R04444,R04445,R05051	RC00080,RC00083,RC00216,RC00242,RC00255	ko00000,ko00001,ko01000,ko03000	-	-	-	Aldedh,Pro_dh,Pro_dh-DNA_bdg
k141_2083_3	945543.VIBR0546_06987	2.91e-85	259.0	COG4230@1|root,COG4230@2|Bacteria,1MYWH@1224|Proteobacteria,1S86Z@1236|Gammaproteobacteria,1XSMU@135623|Vibrionales	135623|Vibrionales	C	COG4230 Delta 1-pyrroline-5-carboxylate dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Aldedh
k141_2083_4	675813.VIB_002562	2.79e-276	765.0	COG0591@1|root,COG0591@2|Bacteria,1MUBI@1224|Proteobacteria,1RMXU@1236|Gammaproteobacteria,1XSU8@135623|Vibrionales	135623|Vibrionales	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	putP	-	-	ko:K11928	-	-	-	-	ko00000,ko02000	2.A.21.2	-	-	SSF
k141_2083_5	318167.Sfri_3868	1.15e-108	318.0	COG0108@1|root,COG0108@2|Bacteria,1MU8P@1224|Proteobacteria,1RQ49@1236|Gammaproteobacteria,2Q9FG@267890|Shewanellaceae	1236|Gammaproteobacteria	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	ribB	GO:0000287,GO:0003674,GO:0003824,GO:0003933,GO:0003935,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0008686,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0016829,GO:0016830,GO:0017144,GO:0018130,GO:0019238,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0042802,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	3.5.4.25,4.1.99.12	ko:K02858,ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	DHBP_synthase,GTP_cyclohydro2
k141_2083_6	1280001.BAOA01000021_gene854	1.41e-67	211.0	COG3722@1|root,COG3722@2|Bacteria,1NEDY@1224|Proteobacteria,1RPCM@1236|Gammaproteobacteria,1XVK5@135623|Vibrionales	135623|Vibrionales	K	Mannitol operon repressor	mtlR	-	-	ko:K02562	-	-	-	-	ko00000,ko03000	-	-	-	MtlR
k141_2083_7	945550.VISI1226_01880	1.43e-183	521.0	COG0246@1|root,COG0246@2|Bacteria,1MXV8@1224|Proteobacteria,1RPCP@1236|Gammaproteobacteria,1XTTE@135623|Vibrionales	135623|Vibrionales	C	hexitol metabolic process	mtlD	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006059,GO:0006066,GO:0008150,GO:0008152,GO:0008926,GO:0009056,GO:0009987,GO:0016052,GO:0016491,GO:0016614,GO:0016616,GO:0019400,GO:0019405,GO:0019407,GO:0019592,GO:0019594,GO:0019751,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044275,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046164,GO:0046174,GO:0055114,GO:0071704,GO:1901575,GO:1901615,GO:1901616	1.1.1.17	ko:K00009	ko00051,map00051	-	R02703	RC00085	ko00000,ko00001,ko01000	-	-	-	Mannitol_dh,Mannitol_dh_C
k141_2083_8	675816.VIA_000213	0.0	933.0	COG2213@1|root,COG4668@1|root,COG2213@2|Bacteria,COG4668@2|Bacteria,1MUPU@1224|Proteobacteria,1RNAG@1236|Gammaproteobacteria,1XSK5@135623|Vibrionales	135623|Vibrionales	G	PTS system mannitol-specific transporter subunit IICBA	mtlA	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0008643,GO:0009401,GO:0015144,GO:0015166,GO:0015318,GO:0015575,GO:0015791,GO:0015797,GO:0015850,GO:0016020,GO:0016740,GO:0016772,GO:0016773,GO:0022804,GO:0022857,GO:0034219,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0090563,GO:1901618	2.7.1.197	ko:K02798,ko:K02799,ko:K02800	ko00051,ko02060,map00051,map02060	M00274	R02704	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.2.1.12,4.A.2.1.2,4.A.2.1.24,4.A.2.1.5	-	-	PTS_EIIA_2,PTS_EIIC,PTS_IIB
k141_1762_1	1121445.ATUZ01000014_gene1566	1.11e-15	71.2	COG1733@1|root,COG1733@2|Bacteria,1N0WG@1224|Proteobacteria,431IT@68525|delta/epsilon subdivisions,2WW6R@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	HxlR-like helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HxlR
k141_1762_2	443144.GM21_2180	1e-10	58.5	COG1942@1|root,COG1942@2|Bacteria,1PAS6@1224|Proteobacteria,43335@68525|delta/epsilon subdivisions,2WXZE@28221|Deltaproteobacteria,43VPB@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Tautomerase enzyme	-	-	5.3.2.6	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	M00569	R03966,R05389	RC01040,RC01355	ko00000,ko00001,ko00002,ko01000	-	-	-	Tautomerase
k141_1762_3	1265505.ATUG01000001_gene3458	5.48e-100	305.0	COG0318@1|root,COG0318@2|Bacteria,1MUMC@1224|Proteobacteria,42P8V@68525|delta/epsilon subdivisions,2WKIF@28221|Deltaproteobacteria,2MJ7Z@213118|Desulfobacterales	28221|Deltaproteobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	6.2.1.44	ko:K00666,ko:K20034	ko00920,map00920	-	R10820	RC00004,RC00014	ko00000,ko00001,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
k141_3498_1	1137799.GZ78_26425	1.4e-36	132.0	COG0673@1|root,COG0673@2|Bacteria,1PDW7@1224|Proteobacteria,1RPU8@1236|Gammaproteobacteria,1XH76@135619|Oceanospirillales	135619|Oceanospirillales	S	oxidoreductase	-	-	1.1.1.335	ko:K13016	ko00520,map00520	-	R10140	RC00182	ko00000,ko00001,ko01000,ko01005	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
k141_3498_2	1485543.JMME01000001_gene1355	4.83e-78	244.0	COG0399@1|root,COG0399@2|Bacteria,1TPDH@1239|Firmicutes,4H2HH@909932|Negativicutes	909932|Negativicutes	E	Belongs to the DegT DnrJ EryC1 family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
k141_1763_1	360107.CHAB381_1197	1.62e-18	89.4	COG2931@1|root,COG2931@2|Bacteria,1RKJ8@1224|Proteobacteria	1224|Proteobacteria	Q	Type I secretion target ggxgxdxxx repeat (2 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,FG-GAP
k141_434_1	1304885.AUEY01000009_gene1942	2.99e-139	418.0	COG0427@1|root,COG0427@2|Bacteria,1Q8ZS@1224|Proteobacteria,42NSQ@68525|delta/epsilon subdivisions,2WK0D@28221|Deltaproteobacteria,2MJ5K@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Acetyl-CoA hydrolase/transferase C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AcetylCoA_hyd_C
k141_434_2	443144.GM21_1355	6.58e-193	548.0	COG0019@1|root,COG0019@2|Bacteria,1MUA6@1224|Proteobacteria,42KZH@68525|delta/epsilon subdivisions,2WIRM@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine	lysA	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
k141_791_25	517418.Ctha_0021	1.03e-74	264.0	COG2202@1|root,COG2203@1|root,COG3887@1|root,COG4251@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG3887@2|Bacteria,COG4251@2|Bacteria,1FFEN@1090|Chlorobi	1090|Chlorobi	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,PAS_3,PAS_9
k141_791_26	306281.AJLK01000029_gene2192	3.32e-32	118.0	COG0784@1|root,COG0784@2|Bacteria,1G63B@1117|Cyanobacteria,1JJBB@1189|Stigonemataceae	1117|Cyanobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
k141_791_27	1408823.AXUS01000016_gene1063	7.24e-296	833.0	COG0557@1|root,COG0557@2|Bacteria,1TQ1G@1239|Firmicutes,247ZS@186801|Clostridia,25QS9@186804|Peptostreptococcaceae	186801|Clostridia	J	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs	rnr	-	-	ko:K12573	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	OB_RNB,RNB,S1
k141_791_28	500633.CLOHIR_00852	1.99e-73	223.0	COG0691@1|root,COG0691@2|Bacteria,1V3IJ@1239|Firmicutes,24HD6@186801|Clostridia,25RAS@186804|Peptostreptococcaceae	186801|Clostridia	O	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA	smpB	-	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
k141_791_29	572546.Arcpr_1769	6.98e-34	123.0	arCOG13036@1|root,arCOG13036@2157|Archaea,2Y25M@28890|Euryarchaeota	28890|Euryarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_791_30	720554.Clocl_0183	1.84e-66	217.0	2BU13@1|root,32P9R@2|Bacteria,1V8XK@1239|Firmicutes,24M09@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_791_31	720554.Clocl_0184	4.21e-115	345.0	COG3344@1|root,COG3344@2|Bacteria,1UZGS@1239|Firmicutes,247Z6@186801|Clostridia,3WIXG@541000|Ruminococcaceae	186801|Clostridia	L	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	RVT_1
k141_1531_1	1379281.AVAG01000012_gene1510	2.34e-62	194.0	COG3794@1|root,COG3794@2|Bacteria,1N3IJ@1224|Proteobacteria,42TYB@68525|delta/epsilon subdivisions,2WR42@28221|Deltaproteobacteria,2MCVC@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	Cytochrome P460	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_P460
k141_561_1	1190603.AJYD01000021_gene208	6.78e-65	207.0	COG0524@1|root,COG0524@2|Bacteria,1MV5B@1224|Proteobacteria,1RNVY@1236|Gammaproteobacteria,1XUEM@135623|Vibrionales	135623|Vibrionales	H	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway	rbsK	-	2.7.1.15	ko:K00852	ko00030,map00030	-	R01051,R02750	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
k141_561_2	1219065.VPR01S_13_00120	2.91e-169	477.0	COG1879@1|root,COG1879@2|Bacteria,1NRXG@1224|Proteobacteria,1RPBV@1236|Gammaproteobacteria,1XUF5@135623|Vibrionales	135623|Vibrionales	G	ABC-type sugar transport system, periplasmic component	rbsB	-	-	ko:K10439	ko02010,ko02030,map02010,map02030	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	Peripla_BP_4
k141_561_3	675814.VIC_002660	2.04e-186	523.0	COG1172@1|root,COG1172@2|Bacteria,1MX7D@1224|Proteobacteria,1RNTS@1236|Gammaproteobacteria,1XTC8@135623|Vibrionales	135623|Vibrionales	G	Belongs to the binding-protein-dependent transport system permease family	rbsC	-	-	ko:K10440	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	BPD_transp_2
k141_561_4	1280001.BAOA01000074_gene3413	4.22e-239	667.0	COG1129@1|root,COG1129@2|Bacteria,1MU22@1224|Proteobacteria,1RMCH@1236|Gammaproteobacteria,1XTBT@135623|Vibrionales	135623|Vibrionales	P	Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system	rbsA	GO:0003674,GO:0003824,GO:0005215,GO:0006810,GO:0008150,GO:0008643,GO:0015144,GO:0015145,GO:0015146,GO:0015399,GO:0015405,GO:0015407,GO:0015591,GO:0015608,GO:0015611,GO:0015749,GO:0015750,GO:0015752,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0034219,GO:0042623,GO:0042626,GO:0043211,GO:0043492,GO:0051119,GO:0051179,GO:0051234,GO:0055085,GO:0071702	3.6.3.17	ko:K10441	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	ABC_tran
k141_4234_1	1232437.KL662073_gene1725	0.0	903.0	COG4666@1|root,COG4666@2|Bacteria,1MUNB@1224|Proteobacteria,42MEV@68525|delta/epsilon subdivisions,2WK2S@28221|Deltaproteobacteria,2MIMQ@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF3394)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3394,DctM
k141_4234_3	1499967.BAYZ01000158_gene448	1.96e-20	103.0	COG0840@1|root,COG0840@2|Bacteria,2NQS9@2323|unclassified Bacteria	2|Bacteria	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	cheD2	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal,dCache_1
k141_4234_4	1396141.BATP01000022_gene375	4.55e-38	134.0	COG4087@1|root,COG4087@2|Bacteria,46WZ9@74201|Verrucomicrobia,2IVV0@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Haloacid dehalogenase domain protein hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_4234_5	933262.AXAM01000046_gene131	1.36e-57	192.0	COG0778@1|root,COG1145@1|root,COG0778@2|Bacteria,COG1145@2|Bacteria,1R42D@1224|Proteobacteria,42Q57@68525|delta/epsilon subdivisions,2WNIW@28221|Deltaproteobacteria,2MIDH@213118|Desulfobacterales	28221|Deltaproteobacteria	C	4Fe-4S ferredoxin iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_4,Fer4_7,Fer4_9,Nitroreductase
k141_4234_6	1232437.KL662050_gene5393	0.000931	48.9	COG1315@1|root,COG1315@2|Bacteria,1R40D@1224|Proteobacteria,42MFE@68525|delta/epsilon subdivisions,2WKAT@28221|Deltaproteobacteria,2MHUI@213118|Desulfobacterales	28221|Deltaproteobacteria	L	polymerase with PALM domain, HD hydrolase domain and Zn ribbon	-	-	-	ko:K09749	-	-	-	-	ko00000	-	-	-	FapA
k141_278_1	1304885.AUEY01000017_gene3714	1.07e-231	665.0	COG3829@1|root,COG3829@2|Bacteria,1N4M6@1224|Proteobacteria,42M38@68525|delta/epsilon subdivisions,2WIR0@28221|Deltaproteobacteria,2MJ85@213118|Desulfobacterales	28221|Deltaproteobacteria	T	sigma-54 factor interaction domain-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,PAS_3,PAS_4,PAS_9,Sigma54_activat
k141_2227_1	243277.VC_1054	1.13e-207	598.0	COG2812@1|root,COG2812@2|Bacteria,1MVCK@1224|Proteobacteria,1RMIA@1236|Gammaproteobacteria,1XV9Y@135623|Vibrionales	135623|Vibrionales	H	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3,DNA_pol3_tau_4,DNA_pol3_tau_5
k141_2227_3	55601.VANGNB10_cI0926	1.2e-161	464.0	COG2204@1|root,COG2204@2|Bacteria,1QUG8@1224|Proteobacteria,1T1Y0@1236|Gammaproteobacteria,1XT04@135623|Vibrionales	135623|Vibrionales	T	COG0784 FOG CheY-like receiver	rssB	-	-	-	-	-	-	-	-	-	-	-	Response_reg
k141_2227_4	1348635.BBJY01000011_gene1211	7.94e-177	496.0	COG0583@1|root,COG0583@2|Bacteria,1R5BA@1224|Proteobacteria,1S4S1@1236|Gammaproteobacteria,1XT26@135623|Vibrionales	135623|Vibrionales	K	Transcriptional regulator	aphB	-	-	ko:K10918	ko05111,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_1,LysR_substrate
k141_4235_2	656519.Halsa_2148	3.66e-26	104.0	COG0601@1|root,COG0601@2|Bacteria,1TP1S@1239|Firmicutes,247IP@186801|Clostridia,3WB7C@53433|Halanaerobiales	186801|Clostridia	P	PFAM binding-protein-dependent transport systems inner membrane component	oppB	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
k141_2503_1	1121403.AUCV01000053_gene2642	2.34e-24	107.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42PJW@68525|delta/epsilon subdivisions,2WJQ3@28221|Deltaproteobacteria,2MPRM@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Bacterial periplasmic substrate-binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Response_reg,SBP_bac_3
k141_3598_1	526222.Desal_1907	1.04e-47	161.0	COG0834@1|root,COG0834@2|Bacteria,1MWDK@1224|Proteobacteria,42NVT@68525|delta/epsilon subdivisions,2WJ9C@28221|Deltaproteobacteria,2M9NJ@213115|Desulfovibrionales	28221|Deltaproteobacteria	ET	extracellular solute-binding protein, family 3	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
k141_3598_2	1307759.JOMJ01000003_gene1158	6.84e-45	154.0	COG0765@1|root,COG0765@2|Bacteria,1MX3E@1224|Proteobacteria,42MFY@68525|delta/epsilon subdivisions,2WJS5@28221|Deltaproteobacteria,2M877@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	polar amino acid ABC transporter, inner membrane subunit	-	-	-	ko:K02029	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	BPD_transp_1
k141_563_1	933262.AXAM01000002_gene539	1.29e-53	174.0	COG0590@1|root,COG0590@2|Bacteria,1RGU0@1224|Proteobacteria,42TVP@68525|delta/epsilon subdivisions,2WQ7U@28221|Deltaproteobacteria,2MK74@213118|Desulfobacterales	28221|Deltaproteobacteria	FJ	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)	tadA	-	3.5.4.33	ko:K11991	-	-	R10223	RC00477	ko00000,ko01000,ko03016	-	-	-	MafB19-deam
k141_563_2	1190606.AJYG01000146_gene1836	1.32e-23	98.6	COG0104@1|root,COG0104@2|Bacteria,1MU5B@1224|Proteobacteria,1RNEW@1236|Gammaproteobacteria,1XU7G@135623|Vibrionales	135623|Vibrionales	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
k141_4641_1	1121451.DESAM_20134	6.36e-233	677.0	COG0438@1|root,COG0613@1|root,COG0438@2|Bacteria,COG0613@2|Bacteria,1MUB7@1224|Proteobacteria,42N14@68525|delta/epsilon subdivisions,2WIKT@28221|Deltaproteobacteria,2M8E0@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
k141_4641_2	86416.Clopa_3526	1.34e-124	374.0	COG0535@1|root,COG0535@2|Bacteria	2|Bacteria	I	radical SAM domain protein	pqqC	-	1.3.3.11	ko:K06137,ko:K06138	-	-	-	-	ko00000,ko01000	-	-	-	Fer4_12,PqqD,Radical_SAM,SPASM,TENA_THI-4
k141_4236_1	1051646.VITU9109_11386	1.32e-22	97.4	COG0037@1|root,COG0037@2|Bacteria,1MU85@1224|Proteobacteria,1RN14@1236|Gammaproteobacteria,1XTTB@135623|Vibrionales	135623|Vibrionales	J	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	6.3.4.19	ko:K04075	-	-	R09597	RC02633,RC02634	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3,TilS,TilS_C
k141_4236_3	1219072.VHA01S_014_00420	2.11e-06	51.2	COG3021@1|root,COG3021@2|Bacteria,1MVPP@1224|Proteobacteria,1RMBH@1236|Gammaproteobacteria,1XTWA@135623|Vibrionales	135623|Vibrionales	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
k141_2228_1	864073.HFRIS_003533	7.08e-06	57.4	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,2VGZ8@28216|Betaproteobacteria	28216|Betaproteobacteria	NT	chemotaxis	-	-	-	ko:K03776	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal,PAS_3,sCache_2
k141_564_1	1307761.L21SP2_2649	1.38e-101	320.0	COG0610@1|root,COG0610@2|Bacteria,2J5UU@203691|Spirochaetes	203691|Spirochaetes	V	Subunit R is required for both nuclease and ATPase activities, but not for modification	hsdR	-	3.1.21.3	ko:K01153	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	DUF3387,EcoR124_C,HSDR_N,ResIII
k141_564_2	866771.HMPREF9296_1122	1.25e-23	102.0	COG0732@1|root,COG0732@2|Bacteria	2|Bacteria	V	type I restriction modification DNA specificity domain	-	-	2.1.1.72,3.1.21.3	ko:K01154,ko:K03427	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HSDR_N_2,Methylase_S,N6_Mtase
k141_1532_1	526222.Desal_3767	4.49e-291	833.0	COG1205@1|root,COG1205@2|Bacteria,1QU0I@1224|Proteobacteria,42M4R@68525|delta/epsilon subdivisions,2WK1V@28221|Deltaproteobacteria,2M8EC@213115|Desulfovibrionales	28221|Deltaproteobacteria	L	DEAD DEAH box helicase domain protein	yprA	-	-	ko:K06877	-	-	-	-	ko00000	-	-	-	DEAD,DUF1998,Helicase_C,RNase_H_2
k141_1915_2	1121935.AQXX01000111_gene5833	1.45e-120	367.0	COG0845@1|root,COG0845@2|Bacteria,1MUI8@1224|Proteobacteria,1RNK4@1236|Gammaproteobacteria,1XIG4@135619|Oceanospirillales	135619|Oceanospirillales	M	secretion protein	-	-	-	ko:K11003	ko03070,ko05133,map03070,map05133	M00325,M00575	-	-	ko00000,ko00001,ko00002,ko02000,ko02044	8.A.1.3.1,8.A.1.3.2	-	-	Biotin_lipoyl_2,HlyD_3
k141_1915_3	1122599.AUGR01000013_gene819	0.0	952.0	COG2274@1|root,COG2274@2|Bacteria,1R2T0@1224|Proteobacteria,1SBE1@1236|Gammaproteobacteria,1XIJU@135619|Oceanospirillales	135619|Oceanospirillales	V	(ABC) transporter	-	-	-	ko:K11004,ko:K13409	ko02010,ko03070,ko04626,ko05133,map02010,map03070,map04626,map05133	M00325,M00339,M00575	-	-	ko00000,ko00001,ko00002,ko02000,ko02044	3.A.1.109.1,3.A.1.109.2,3.A.1.110	-	-	ABC_membrane,ABC_tran,Peptidase_C39
k141_1915_4	595494.Tola_2137	2.44e-63	207.0	COG1820@1|root,COG1820@2|Bacteria,1MW8Y@1224|Proteobacteria,1RMRV@1236|Gammaproteobacteria,1Y3SZ@135624|Aeromonadales	135624|Aeromonadales	G	Belongs to the metallo-dependent hydrolases superfamily. NagA family	nagA	-	3.5.1.25	ko:K01443	ko00520,ko01130,map00520,map01130	-	R02059	RC00166,RC00300	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
k141_792_4	1348635.BBJY01000004_gene2985	1.48e-123	356.0	COG0132@1|root,COG0132@2|Bacteria,1RDRK@1224|Proteobacteria,1RSHS@1236|Gammaproteobacteria,1XSF9@135623|Vibrionales	135623|Vibrionales	H	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring	bioD	GO:0003674,GO:0003824,GO:0004141,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0017144,GO:0018130,GO:0019752,GO:0032787,GO:0034641,GO:0042364,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.3.3	ko:K01935	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03182	RC00868	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_26
k141_792_5	1219076.N646_0166	1.84e-106	316.0	COG0500@1|root,COG2226@2|Bacteria,1PA5F@1224|Proteobacteria,1RY7A@1236|Gammaproteobacteria,1XTUZ@135623|Vibrionales	135623|Vibrionales	H	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway	bioC	-	2.1.1.197	ko:K02169	ko00780,ko01100,map00780,map01100	M00572	R09543	RC00003,RC00460	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11
k141_3599_2	870967.VIS19158_22172	3.96e-282	776.0	COG0486@1|root,COG0486@2|Bacteria,1MUCQ@1224|Proteobacteria,1RN5S@1236|Gammaproteobacteria,1XTKD@135623|Vibrionales	135623|Vibrionales	J	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34	mnmE	GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009636,GO:0009987,GO:0010467,GO:0016070,GO:0034470,GO:0034641,GO:0034660,GO:0042221,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0050896,GO:0071704,GO:0090304,GO:1901360	-	ko:K03650	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko01000,ko03016	-	-	-	MMR_HSR1,MnmE_helical,TrmE_N
k141_3599_3	29495.EA26_00690	3.11e-73	222.0	COG0369@1|root,COG0369@2|Bacteria,1QUGM@1224|Proteobacteria,1T1YC@1236|Gammaproteobacteria,1XWYJ@135623|Vibrionales	135623|Vibrionales	P	COG0716 Flavodoxins	mioC	GO:0003674,GO:0003824,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016491,GO:0022900,GO:0044237,GO:0055114	-	ko:K06205	-	-	-	-	ko00000	-	-	-	Flavodoxin_1
k141_2504_1	1265505.ATUG01000003_gene198	2.12e-12	67.0	COG0548@1|root,COG0548@2|Bacteria,1MU17@1224|Proteobacteria,42N8G@68525|delta/epsilon subdivisions,2WKBC@28221|Deltaproteobacteria,2MI9G@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Belongs to the acetylglutamate kinase family. ArgB subfamily	argB	GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.2.8	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R02649	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
k141_2504_2	1304885.AUEY01000138_gene215	1.18e-281	778.0	COG2368@1|root,COG2368@2|Bacteria,1PEQG@1224|Proteobacteria,42NUH@68525|delta/epsilon subdivisions,2WISE@28221|Deltaproteobacteria,2MI4T@213118|Desulfobacterales	28221|Deltaproteobacteria	Q	PFAM 4-hydroxyphenylacetate 3-hydroxylase N terminal	-	-	4.2.1.120,5.3.3.3	ko:K14534	ko00650,ko00720,ko01100,ko01120,ko01200,map00650,map00720,map01100,map01120,map01200	M00374,M00375	R03031,R10782	RC01857,RC03277	ko00000,ko00001,ko00002,ko01000	-	-	-	HpaB,HpaB_N
k141_2504_4	1304885.AUEY01000138_gene213	3.34e-111	325.0	COG1028@1|root,COG1028@2|Bacteria,1MWGC@1224|Proteobacteria,42QH3@68525|delta/epsilon subdivisions,2WKXH@28221|Deltaproteobacteria,2MJC1@213118|Desulfobacterales	28221|Deltaproteobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
k141_4951_19	1348635.BBJY01000009_gene1447	3.99e-312	853.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria,1XUQI@135623|Vibrionales	135623|Vibrionales	T	COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains	glnG	-	-	ko:K07712	ko02020,map02020	M00497	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
k141_4951_20	1219077.VAZ01S_028_00070	9.5e-163	464.0	COG1816@1|root,COG1816@2|Bacteria,1MWBV@1224|Proteobacteria,1RNVI@1236|Gammaproteobacteria,1XU9B@135623|Vibrionales	135623|Vibrionales	F	COG1816 Adenosine deaminase	add	GO:0003674,GO:0003824,GO:0004000,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006144,GO:0006152,GO:0006154,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009113,GO:0009116,GO:0009119,GO:0009163,GO:0009164,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017144,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042278,GO:0042440,GO:0042451,GO:0042454,GO:0042455,GO:0042737,GO:0043094,GO:0043096,GO:0043101,GO:0043103,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046085,GO:0046100,GO:0046101,GO:0046102,GO:0046103,GO:0046112,GO:0046128,GO:0046129,GO:0046130,GO:0046148,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0072523,GO:1901135,GO:1901136,GO:1901137,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901657,GO:1901658,GO:1901659	3.5.4.4	ko:K01488	ko00230,ko01100,ko05340,map00230,map01100,map05340	-	R01560,R02556	RC00477	ko00000,ko00001,ko01000	-	-	-	A_deaminase
k141_1546_1	1121396.KB893103_gene1771	2.94e-68	231.0	COG1033@1|root,COG1033@2|Bacteria,1MUE1@1224|Proteobacteria,42ME2@68525|delta/epsilon subdivisions,2WJRI@28221|Deltaproteobacteria,2MMR2@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Sterol-sensing domain of SREBP cleavage-activation	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	GGDEF,LolA_like,MMPL,cNMP_binding
k141_5214_1	1501230.ET33_36240	2.28e-71	229.0	COG1131@1|root,COG1131@2|Bacteria,1TP4J@1239|Firmicutes,4HBGH@91061|Bacilli,26QWM@186822|Paenibacillaceae	91061|Bacilli	V	ABC transporter, ATP-binding protein	bcrA	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
k141_294_1	1536774.H70357_11725	7.41e-84	255.0	COG1515@1|root,COG1515@2|Bacteria,1V1CJ@1239|Firmicutes,4HEAW@91061|Bacilli,26SVA@186822|Paenibacillaceae	91061|Bacilli	L	DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA	nfi	-	3.1.21.7	ko:K05982	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	Endonuclease_5
k141_582_1	1121403.AUCV01000097_gene2087	2.53e-65	206.0	COG2230@1|root,COG2230@2|Bacteria,1R2HP@1224|Proteobacteria	1224|Proteobacteria	M	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_826_1	484770.UFO1_3397	4e-75	231.0	COG0664@1|root,COG0664@2|Bacteria,1V2E0@1239|Firmicutes,4H8QC@909932|Negativicutes	909932|Negativicutes	T	cyclic nucleotide-binding	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_4952_1	756067.MicvaDRAFT_2242	3.58e-39	153.0	COG3290@1|root,COG4191@1|root,COG5000@1|root,COG3290@2|Bacteria,COG4191@2|Bacteria,COG5000@2|Bacteria,1G07W@1117|Cyanobacteria,1H7H2@1150|Oscillatoriales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,PAS_4,PAS_9
k141_1933_1	1205908.AKXW01000020_gene1071	4.67e-35	134.0	COG2214@1|root,COG2214@2|Bacteria,1N0RS@1224|Proteobacteria,1SAUA@1236|Gammaproteobacteria,1Y0XP@135623|Vibrionales	135623|Vibrionales	O	Heat shock protein DnaJ domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_1933_2	55601.VANGNB10_cI0363	5.31e-231	666.0	COG3501@1|root,COG3501@2|Bacteria,1MU7Q@1224|Proteobacteria,1RMZS@1236|Gammaproteobacteria,1XUHW@135623|Vibrionales	135623|Vibrionales	M	protein conserved in bacteria	vgrG1	GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0006464,GO:0006807,GO:0006996,GO:0007010,GO:0007015,GO:0008144,GO:0008150,GO:0008152,GO:0008154,GO:0009405,GO:0009987,GO:0016043,GO:0016874,GO:0016879,GO:0016881,GO:0017076,GO:0018149,GO:0018153,GO:0018193,GO:0018199,GO:0018205,GO:0018262,GO:0018995,GO:0019538,GO:0022411,GO:0030029,GO:0030036,GO:0030042,GO:0030430,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032984,GO:0033643,GO:0033646,GO:0035639,GO:0036094,GO:0036211,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0043624,GO:0043656,GO:0043657,GO:0043933,GO:0044215,GO:0044216,GO:0044217,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044419,GO:0046872,GO:0051261,GO:0051704,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:0097435,GO:1901265,GO:1901363,GO:1901564	-	ko:K11904	ko03070,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	PG_binding_1,Phage_GPD
k141_1933_4	314278.NB231_12129	6.66e-64	211.0	COG5351@1|root,COG5351@2|Bacteria,1R3ZF@1224|Proteobacteria,1S0MS@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF2169
k141_295_2	572547.Amico_0168	1.41e-32	126.0	COG0053@1|root,COG0053@2|Bacteria,3T9ZH@508458|Synergistetes	508458|Synergistetes	P	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
k141_1934_1	870187.Thini_0232	4.11e-53	173.0	COG0727@1|root,COG0727@2|Bacteria,1N1JR@1224|Proteobacteria,1SUCZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Putative zinc- or iron-chelating domain	-	-	-	-	-	-	-	-	-	-	-	-	CxxCxxCC
k141_3228_1	1121405.dsmv_2238	6.55e-191	540.0	COG5557@1|root,COG5557@2|Bacteria,1PFX4@1224|Proteobacteria,42NUN@68525|delta/epsilon subdivisions,2WJHN@28221|Deltaproteobacteria,2MHX4@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM Polysulphide reductase, NrfD	dsrP	-	-	ko:K00185	-	-	-	-	ko00000	5.A.3	-	-	NrfD
k141_3228_2	1304885.AUEY01000002_gene404	3.34e-108	318.0	COG0437@1|root,COG0437@2|Bacteria,1NBU3@1224|Proteobacteria,42MNU@68525|delta/epsilon subdivisions,2WJRG@28221|Deltaproteobacteria,2MIME@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein	dsrO	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_11,Fer4_4
k141_297_1	1517681.HW45_16890	6.92e-61	195.0	COG1349@1|root,COG1349@2|Bacteria,1MUJG@1224|Proteobacteria,1RPS0@1236|Gammaproteobacteria,1XSYQ@135623|Vibrionales	135623|Vibrionales	K	COG1349 Transcriptional regulators of sugar metabolism	-	-	-	ko:K02444	-	-	-	-	ko00000,ko03000	-	-	-	DeoRC,HTH_DeoR
k141_3626_1	465817.ETA_13990	9.44e-53	175.0	COG2188@1|root,COG2188@2|Bacteria,1Q856@1224|Proteobacteria,1RQ3N@1236|Gammaproteobacteria,3X6XE@551|Erwinia	1236|Gammaproteobacteria	K	Transcriptional regulator	phnF	-	-	ko:K02043,ko:K03482	-	-	-	-	ko00000,ko03000	-	-	-	GntR,UTRA
k141_3626_2	382245.ASA_4276	2.67e-246	691.0	COG1263@1|root,COG1264@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,1MU2P@1224|Proteobacteria,1RNF4@1236|Gammaproteobacteria,1Y51Y@135624|Aeromonadales	135624|Aeromonadales	G	phosphotransferase system, EIIB	-	-	2.7.1.208	ko:K02749,ko:K02750	ko00500,ko02060,map00500,map02060	M00268	R04111	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.1.1.10,4.A.1.1.16,4.A.1.1.4,4.A.1.1.8	-	-	PTS_EIIB,PTS_EIIC
k141_3626_3	1348635.BBJY01000010_gene1442	1.19e-283	779.0	COG1486@1|root,COG1486@2|Bacteria,1NI6G@1224|Proteobacteria,1RYKZ@1236|Gammaproteobacteria,1Y2BR@135623|Vibrionales	135623|Vibrionales	G	COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases	-	-	3.2.1.122	ko:K01232	ko00500,map00500	-	R00837,R00838,R06113	RC00049	ko00000,ko00001,ko01000	-	GH4	-	Glyco_hydro_4,Glyco_hydro_4C
k141_1260_1	675813.VIB_000834	2.33e-25	98.2	2ER47@1|root,33IPS@2|Bacteria,1NHAY@1224|Proteobacteria,1SH4T@1236|Gammaproteobacteria,1XX51@135623|Vibrionales	135623|Vibrionales	S	Protein of unknown function (DUF2802)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2802
k141_1260_2	243277.VC_2048	5.87e-106	315.0	COG2853@1|root,COG2853@2|Bacteria,1MVX0@1224|Proteobacteria,1RNPS@1236|Gammaproteobacteria,1XV65@135623|Vibrionales	135623|Vibrionales	M	COG2853 Surface lipoprotein	vacJ	-	-	ko:K04754	-	-	-	-	ko00000	-	-	-	MlaA
k141_1260_3	1187848.AJYQ01000101_gene1129	1.25e-62	201.0	COG1028@1|root,COG1028@2|Bacteria,1QJGM@1224|Proteobacteria,1THGE@1236|Gammaproteobacteria,1XVMG@135623|Vibrionales	135623|Vibrionales	IQ	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	VP2120	-	-	-	-	-	-	-	-	-	-	-	adh_short
k141_1260_4	1051646.VITU9109_20611	4.05e-39	137.0	2EIW7@1|root,33CMH@2|Bacteria,1NIEH@1224|Proteobacteria,1SGBR@1236|Gammaproteobacteria,1XSI3@135623|Vibrionales	135623|Vibrionales	S	Ribosomal S4P (gammaproteobacterial)	VV1177	-	-	-	-	-	-	-	-	-	-	-	Ribosomal_S4Pg
k141_1260_5	675815.VOA_002391	7.58e-132	374.0	COG0605@1|root,COG0605@2|Bacteria,1MVW2@1224|Proteobacteria,1RP7X@1236|Gammaproteobacteria,1XTPM@135623|Vibrionales	135623|Vibrionales	C	Destroys radicals which are normally produced within the cells and which are toxic to biological systems	sodB	-	1.15.1.1	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Fe_C,Sod_Fe_N
k141_1260_6	55601.VANGNB10_cI1856c	4.86e-68	206.0	COG0278@1|root,COG0278@2|Bacteria,1MZ4V@1224|Proteobacteria,1S640@1236|Gammaproteobacteria,1XXC2@135623|Vibrionales	135623|Vibrionales	C	Belongs to the glutaredoxin family. Monothiol subfamily	grxD	-	-	ko:K07390	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Glutaredoxin
k141_4646_1	55601.VANGNB10_cI2344c	8.65e-159	446.0	COG0092@1|root,COG0092@2|Bacteria,1MUAI@1224|Proteobacteria,1RN0P@1236|Gammaproteobacteria,1XSCE@135623|Vibrionales	135623|Vibrionales	J	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation	rpsC	GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02982	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KH_2,Ribosomal_S3_C
k141_4646_2	1219065.VPR01S_04_00940	2.95e-85	252.0	COG0197@1|root,COG0197@2|Bacteria,1RA0Z@1224|Proteobacteria,1S201@1236|Gammaproteobacteria,1XWVR@135623|Vibrionales	135623|Vibrionales	J	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs	rplP	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02878	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L16
k141_4646_3	575788.VS_2823	4.37e-31	109.0	COG0255@1|root,COG0255@2|Bacteria,1N6PR@1224|Proteobacteria,1SCBN@1236|Gammaproteobacteria,1XYAY@135623|Vibrionales	135623|Vibrionales	J	Belongs to the universal ribosomal protein uL29 family	rpmC	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02904	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L29
k141_4646_4	55601.VANGNB10_cI2341c	2.68e-50	159.0	COG0186@1|root,COG0186@2|Bacteria,1MZIK@1224|Proteobacteria,1S8SS@1236|Gammaproteobacteria,1XXXG@135623|Vibrionales	135623|Vibrionales	J	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA	rpsQ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02961	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S17
k141_4646_5	314292.VAS14_19261	3.35e-78	233.0	COG0093@1|root,COG0093@2|Bacteria,1RCWZ@1224|Proteobacteria,1S3Z3@1236|Gammaproteobacteria,1XX0D@135623|Vibrionales	135623|Vibrionales	J	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome	rplN	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02874	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L14
k141_4646_6	1219080.VEZ01S_05_01860	5.14e-62	191.0	COG0198@1|root,COG0198@2|Bacteria,1MZQD@1224|Proteobacteria,1S973@1236|Gammaproteobacteria,1XX9Z@135623|Vibrionales	135623|Vibrionales	J	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit	rplX	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02895	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KOW,ribosomal_L24
k141_4646_7	1219080.VEZ01S_05_01850	3.67e-118	338.0	COG0094@1|root,COG0094@2|Bacteria,1MUU9@1224|Proteobacteria,1RPE1@1236|Gammaproteobacteria,1XTAU@135623|Vibrionales	135623|Vibrionales	J	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits	rplE	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02931	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L5,Ribosomal_L5_C
k141_4646_8	55601.VANGNB10_cI2337c	9.45e-61	187.0	COG0199@1|root,COG0199@2|Bacteria,1MZDT@1224|Proteobacteria,1S62N@1236|Gammaproteobacteria,1XXE9@135623|Vibrionales	135623|Vibrionales	J	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site	rpsN	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02954	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S14
k141_1935_1	903814.ELI_4035	1.58e-65	207.0	COG0087@1|root,COG0087@2|Bacteria,1TPFT@1239|Firmicutes,247NH@186801|Clostridia,25VIA@186806|Eubacteriaceae	186801|Clostridia	J	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit	rplC	-	-	ko:K02906	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L3
k141_1935_2	1304885.AUEY01000001_gene3246	1.38e-21	90.1	COG0088@1|root,COG0088@2|Bacteria,1MXPF@1224|Proteobacteria,42MPW@68525|delta/epsilon subdivisions,2WN96@28221|Deltaproteobacteria,2MJHZ@213118|Desulfobacterales	28221|Deltaproteobacteria	J	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome	rplD	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02926	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L4
k141_4953_1	223926.28808540	6.15e-185	522.0	COG0252@1|root,COG0252@2|Bacteria,1MWIR@1224|Proteobacteria,1RNPN@1236|Gammaproteobacteria,1XVJW@135623|Vibrionales	135623|Vibrionales	EJ	Belongs to the asparaginase 1 family	ansB	-	3.5.1.1	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	-	R00485	RC00010,RC02798	ko00000,ko00001,ko01000	-	-	-	Asparaginase
k141_828_1	1123279.ATUS01000001_gene1553	1.35e-37	152.0	COG1629@1|root,COG4771@2|Bacteria,1MXAE@1224|Proteobacteria,1RWWH@1236|Gammaproteobacteria,1J9I1@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	P	TonB-dependent Receptor Plug Domain	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
k141_5215_1	1304885.AUEY01000024_gene2703	1.38e-128	415.0	COG0457@1|root,COG2604@1|root,COG0457@2|Bacteria,COG2604@2|Bacteria,1R4P0@1224|Proteobacteria,42NB8@68525|delta/epsilon subdivisions,2WM4Q@28221|Deltaproteobacteria,2MJAP@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Protein of unknown function DUF115	-	-	-	-	-	-	-	-	-	-	-	-	MAF_flag10,TPR_16,TPR_2,TPR_8
k141_4954_1	1236542.BALM01000001_gene253	5.1e-20	89.0	COG3572@1|root,COG3572@2|Bacteria,1N0R0@1224|Proteobacteria,1S9DH@1236|Gammaproteobacteria,2QC2B@267890|Shewanellaceae	1236|Gammaproteobacteria	H	Chalcone isomerase-like	-	-	-	-	-	-	-	-	-	-	-	-	Chalcone_3
k141_1547_1	207559.Dde_0299	2.24e-52	172.0	COG3005@1|root,COG3005@2|Bacteria,1RIC0@1224|Proteobacteria,42NW0@68525|delta/epsilon subdivisions,2WK0R@28221|Deltaproteobacteria,2MB00@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	Cytochrome c-type protein	-	-	-	ko:K02569,ko:K03532	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	5.A.3.4	-	-	Cytochrom_NNT
k141_2667_4	1348635.BBJY01000007_gene233	2.8e-168	474.0	COG1175@1|root,COG1175@2|Bacteria,1MVAP@1224|Proteobacteria,1SZMU@1236|Gammaproteobacteria,1Y2WD@135623|Vibrionales	135623|Vibrionales	G	Binding-protein-dependent transport system inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
k141_2667_5	1348635.BBJY01000007_gene234	5.02e-172	485.0	COG0395@1|root,COG0395@2|Bacteria,1MUWS@1224|Proteobacteria,1RPCG@1236|Gammaproteobacteria,1XWQN@135623|Vibrionales	135623|Vibrionales	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K05815	ko02010,map02010	M00198	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.3	-	-	BPD_transp_1
k141_2667_6	1348635.BBJY01000007_gene235	2.22e-250	694.0	COG1653@1|root,COG1653@2|Bacteria,1R5H8@1224|Proteobacteria,1RZ6J@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1,SBP_bac_8
k141_2667_7	1348635.BBJY01000007_gene236	5.27e-96	289.0	COG1609@1|root,COG1609@2|Bacteria,1R7GP@1224|Proteobacteria,1RQ7P@1236|Gammaproteobacteria,1XV5G@135623|Vibrionales	135623|Vibrionales	K	Bacterial regulatory proteins, lacI family	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
k141_4392_6	1443125.Z962_03380	8.21e-56	178.0	COG0716@1|root,COG0716@2|Bacteria,1V6D7@1239|Firmicutes,24J7W@186801|Clostridia,36JTC@31979|Clostridiaceae	186801|Clostridia	C	flavodoxin	-	-	-	-	-	-	-	-	-	-	-	-	Flavodoxin_1
k141_4392_7	1151292.QEW_0214	5.58e-79	249.0	COG1893@1|root,COG1893@2|Bacteria,1UM1M@1239|Firmicutes,249J4@186801|Clostridia,25TFV@186804|Peptostreptococcaceae	186801|Clostridia	H	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid	-	-	1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000	-	-	-	ApbA,ApbA_C
k141_4392_8	350688.Clos_2290	1.98e-301	884.0	COG1074@1|root,COG1074@2|Bacteria,1TQ35@1239|Firmicutes,248ZF@186801|Clostridia,36E2W@31979|Clostridiaceae	186801|Clostridia	L	ATP-dependent helicase nuclease subunit A	addA	-	3.6.4.12	ko:K16898	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
k141_4392_9	335541.Swol_1142	2.47e-214	653.0	COG3857@1|root,COG3857@2|Bacteria,1TQJW@1239|Firmicutes,2487T@186801|Clostridia,42JQK@68298|Syntrophomonadaceae	186801|Clostridia	L	Belongs to the helicase family. AddB RexB type 1 subfamily	addB	-	3.6.4.12	ko:K16899	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	Exonuc_V_gamma,PDDEXK_1,UvrD-helicase,UvrD_C
k141_4392_11	457396.CSBG_01848	2.14e-96	286.0	COG0572@1|root,COG0572@2|Bacteria,1TQ4V@1239|Firmicutes,24850@186801|Clostridia,36DNP@31979|Clostridiaceae	186801|Clostridia	F	Cytidine monophosphokinase	udk	-	2.7.1.48	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R00513,R00516,R00517,R00962,R00964,R00967,R00968,R00970,R01548,R01549,R01880,R02091,R02096,R02097,R02327,R02332,R02371,R02372,R08232	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PRK
k141_4392_12	1121324.CLIT_23c04170	6.29e-202	570.0	COG0826@1|root,COG0826@2|Bacteria,1TPRE@1239|Firmicutes,248I3@186801|Clostridia,25QJC@186804|Peptostreptococcaceae	186801|Clostridia	O	Peptidase, U32 family	yhbU_1	-	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_U32,Peptidase_U32_C
k141_4392_13	500633.CLOHIR_01160	1.32e-78	241.0	COG4122@1|root,COG4122@2|Bacteria,1UF4M@1239|Firmicutes,24B70@186801|Clostridia,25ST0@186804|Peptostreptococcaceae	186801|Clostridia	S	O-methyltransferase	yrrM	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_3
k141_4392_14	1286171.EAL2_c12220	6.61e-93	287.0	COG1559@1|root,COG1559@2|Bacteria,1TS48@1239|Firmicutes,2493B@186801|Clostridia,25VD2@186806|Eubacteriaceae	186801|Clostridia	M	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation	mltG	-	-	ko:K07082	-	-	-	-	ko00000	-	-	-	YceG
k141_4392_15	1476973.JMMB01000007_gene988	2.15e-208	588.0	COG0213@1|root,COG0213@2|Bacteria,1TPCH@1239|Firmicutes,24848@186801|Clostridia,25T0Q@186804|Peptostreptococcaceae	186801|Clostridia	F	Pyrimidine nucleoside phosphorylase C-terminal domain	pdp	-	2.4.2.2,2.4.2.4	ko:K00756,ko:K00758	ko00240,ko00983,ko01100,ko05219,map00240,map00983,map01100,map05219	-	R01570,R01876,R02296,R02484,R08222,R08230	RC00063	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS08925	Glycos_trans_3N,Glycos_transf_3,PYNP_C
k141_4392_16	398511.BpOF4_14770	4.82e-116	341.0	COG0005@1|root,COG0005@2|Bacteria,1TQ37@1239|Firmicutes,4HABP@91061|Bacilli,1ZEQS@1386|Bacillus	91061|Bacilli	F	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate	punA	-	2.4.2.1,2.4.2.28	ko:K00772,ko:K03783	ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110	M00034	R01402,R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244	RC00033,RC00063,RC00122,RC02819	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
k141_4392_17	1301100.HG529268_gene607	3.75e-137	394.0	COG0005@1|root,COG0005@2|Bacteria,1TQ37@1239|Firmicutes,247KQ@186801|Clostridia,36E47@31979|Clostridiaceae	186801|Clostridia	F	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate	punA	-	2.4.2.1	ko:K03783	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244	RC00033,RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
k141_4392_18	1292035.H476_1985	3.95e-206	578.0	COG1015@1|root,COG1015@2|Bacteria,1TP70@1239|Firmicutes,247WB@186801|Clostridia,25QPX@186804|Peptostreptococcaceae	186801|Clostridia	G	Phosphotransfer between the C1 and C5 carbon atoms of pentose	deoB	-	5.4.2.7	ko:K01839	ko00030,ko00230,map00030,map00230	-	R01057,R02749	RC00408	ko00000,ko00001,ko01000	-	-	-	Metalloenzyme
k141_4392_19	1151292.QEW_1600	1.98e-91	280.0	COG4974@1|root,COG4974@2|Bacteria,1TQRG@1239|Firmicutes,247QQ@186801|Clostridia,25QDH@186804|Peptostreptococcaceae	186801|Clostridia	L	Belongs to the 'phage' integrase family	xerC	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
k141_4392_20	1128398.Curi_c14020	4.9e-66	207.0	COG0494@1|root,COG0494@2|Bacteria,1V6F5@1239|Firmicutes,24JFS@186801|Clostridia,268ZS@186813|unclassified Clostridiales	186801|Clostridia	L	NUDIX domain	nudF	-	3.6.1.13	ko:K01515	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
k141_4392_21	445973.CLOBAR_02242	3.12e-131	386.0	COG3502@1|root,COG3502@2|Bacteria,1TQW1@1239|Firmicutes,24952@186801|Clostridia,25R2G@186804|Peptostreptococcaceae	186801|Clostridia	S	Protein of unknown function (DUF3866)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3866
k141_4392_22	445973.CLOBAR_02243	2.67e-56	189.0	COG0472@1|root,COG0472@2|Bacteria,1V7C4@1239|Firmicutes,24K6E@186801|Clostridia,25R28@186804|Peptostreptococcaceae	186801|Clostridia	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_4
k141_4392_23	1511.CLOST_1337	8.47e-71	223.0	COG1215@1|root,COG1215@2|Bacteria,1TPBB@1239|Firmicutes,25KCB@186801|Clostridia,25QQF@186804|Peptostreptococcaceae	186801|Clostridia	M	Glycosyltransferase, group 2 family protein	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
k141_4392_24	1121324.CLIT_23c04090	5.56e-62	204.0	28JWD@1|root,2Z9M5@2|Bacteria,1UZF1@1239|Firmicutes,24HZN@186801|Clostridia,25T02@186804|Peptostreptococcaceae	186801|Clostridia	S	Copper transport outer membrane protein, MctB	-	-	-	-	-	-	-	-	-	-	-	-	MctB
k141_4392_25	1286171.EAL2_c12150	6.2e-159	457.0	COG4825@1|root,COG4825@2|Bacteria,1TQ8Q@1239|Firmicutes,24B4X@186801|Clostridia	186801|Clostridia	S	PFAM Thiamin pyrophosphokinase catalytic	-	-	-	-	-	-	-	-	-	-	-	-	MAF_flag10,TPPK_C
k141_4392_26	37659.JNLN01000001_gene2420	5.43e-92	280.0	COG0745@1|root,COG0745@2|Bacteria,1TPF7@1239|Firmicutes,24916@186801|Clostridia,36EFI@31979|Clostridiaceae	186801|Clostridia	KT	May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process	spo0A	-	-	ko:K07699	ko02020,ko02024,map02020,map02024	M00485	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Spo0A_C
k141_4392_27	500633.CLOHIR_01151	2.92e-141	427.0	COG0497@1|root,COG0497@2|Bacteria,1TP99@1239|Firmicutes,247KB@186801|Clostridia,25QYR@186804|Peptostreptococcaceae	186801|Clostridia	L	May be involved in recombinational repair of damaged DNA	recN	-	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,SMC_N
k141_4392_28	1286171.EAL2_c12060	1.61e-65	203.0	COG1438@1|root,COG1438@2|Bacteria,1V1R7@1239|Firmicutes,24HGQ@186801|Clostridia,25WB7@186806|Eubacteriaceae	186801|Clostridia	K	Regulates arginine biosynthesis genes	argR	-	-	ko:K03402	-	-	-	-	ko00000,ko03000	-	-	-	Arg_repressor,Arg_repressor_C
k141_4392_29	1499684.CCNP01000020_gene2307	1.91e-120	352.0	COG1189@1|root,COG1189@2|Bacteria,1TPE4@1239|Firmicutes,247VH@186801|Clostridia,36EDU@31979|Clostridiaceae	186801|Clostridia	J	Methyltransferase	rrmJ	-	2.1.1.226,2.1.1.227	ko:K06442	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ,S4
k141_4392_30	1121324.CLIT_23c03870	7.11e-263	741.0	COG1154@1|root,COG1154@2|Bacteria,1TP37@1239|Firmicutes,247P1@186801|Clostridia,25QT2@186804|Peptostreptococcaceae	186801|Clostridia	H	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)	dxs	-	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	-	DXP_synthase_N,Transket_pyr,Transketolase_C
k141_4392_31	1304284.L21TH_0189	1.34e-34	128.0	COG1253@1|root,COG1253@2|Bacteria,1VBH3@1239|Firmicutes,24NJQ@186801|Clostridia,36IUM@31979|Clostridiaceae	186801|Clostridia	S	flavin adenine dinucleotide binding	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_4392_32	1121324.CLIT_23c03850	4.06e-64	199.0	COG1963@1|root,COG1963@2|Bacteria,1VAVC@1239|Firmicutes,24MV7@186801|Clostridia,25RHI@186804|Peptostreptococcaceae	186801|Clostridia	S	Divergent PAP2 family	-	-	-	ko:K09775	-	-	-	-	ko00000	-	-	-	DUF212
k141_4392_33	1301100.HG529233_gene7387	3.72e-117	345.0	COG0142@1|root,COG0142@2|Bacteria,1TPQY@1239|Firmicutes,248DE@186801|Clostridia,36EGM@31979|Clostridiaceae	186801|Clostridia	H	Belongs to the FPP GGPP synthase family	ispA	-	2.5.1.1,2.5.1.10,2.5.1.29	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00366	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	iHN637.CLJU_RS05465	polyprenyl_synt
k141_4392_34	1121324.CLIT_23c03830	2.17e-12	63.2	COG1722@1|root,COG1722@2|Bacteria,1VK9I@1239|Firmicutes,24UH5@186801|Clostridia	186801|Clostridia	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseB	-	3.1.11.6	ko:K03602	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_S
k141_4392_35	1121324.CLIT_23c03820	1.45e-114	347.0	COG1570@1|root,COG1570@2|Bacteria,1TP4E@1239|Firmicutes,247KE@186801|Clostridia,25QJ1@186804|Peptostreptococcaceae	186801|Clostridia	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseA	-	3.1.11.6	ko:K03601	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
k141_4392_36	500633.CLOHIR_01144	9.5e-76	242.0	COG0533@1|root,COG0533@2|Bacteria,1TRPY@1239|Firmicutes,24CN4@186801|Clostridia,25SPG@186804|Peptostreptococcaceae	186801|Clostridia	O	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	gcp1	-	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
k141_4392_37	1161902.HMPREF0378_0564	2.62e-23	94.7	COG0781@1|root,COG0781@2|Bacteria,1VA9B@1239|Firmicutes,24MQ3@186801|Clostridia,3WDJZ@538999|Clostridiales incertae sedis	186801|Clostridia	K	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons	nusB	-	-	ko:K03625	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusB
k141_4392_38	1121324.CLIT_23c03790	6.47e-49	159.0	COG1302@1|root,COG1302@2|Bacteria,1V4IC@1239|Firmicutes,24JNM@186801|Clostridia,25RIH@186804|Peptostreptococcaceae	186801|Clostridia	S	Asp23 family, cell envelope-related function	asp	-	-	-	-	-	-	-	-	-	-	-	Asp23
k141_4392_41	880070.Cycma_2302	1.96e-33	120.0	COG2315@1|root,COG2315@2|Bacteria,4NS6J@976|Bacteroidetes,47R6I@768503|Cytophagia	976|Bacteroidetes	S	YjbR	-	-	-	-	-	-	-	-	-	-	-	-	YjbR
k141_4392_42	536227.CcarbDRAFT_2200	2.15e-81	242.0	COG5561@1|root,COG5561@2|Bacteria,1VE2W@1239|Firmicutes,24HE2@186801|Clostridia,36ISA@31979|Clostridiaceae	186801|Clostridia	S	metal-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	CGGC
k141_4392_43	293826.Amet_0846	0.0	910.0	COG1196@1|root,COG1196@2|Bacteria,1UZCT@1239|Firmicutes,24FJ5@186801|Clostridia	186801|Clostridia	D	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	AAA_23
k141_4392_44	293826.Amet_0845	2.02e-71	220.0	2EQ8E@1|root,33HUP@2|Bacteria,1VPWX@1239|Firmicutes,2520Z@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_4392_45	293826.Amet_0844	8.61e-170	489.0	2DCK4@1|root,32TZT@2|Bacteria,1VCBP@1239|Firmicutes,24ZG9@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_4392_46	1391646.AVSU01000032_gene2323	3.89e-220	616.0	COG0304@1|root,COG0304@2|Bacteria,1TPA7@1239|Firmicutes,247VF@186801|Clostridia,25QQD@186804|Peptostreptococcaceae	186801|Clostridia	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabF	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
k141_4392_47	293826.Amet_1223	6.49e-27	100.0	COG0236@1|root,COG0236@2|Bacteria,1VEE3@1239|Firmicutes,24QME@186801|Clostridia	186801|Clostridia	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
k141_4392_48	1408823.AXUS01000005_gene2546	3.12e-95	286.0	COG1028@1|root,COG1028@2|Bacteria,1TP76@1239|Firmicutes,247PV@186801|Clostridia,25R8Y@186804|Peptostreptococcaceae	186801|Clostridia	IQ	3-oxoacyl- acyl-carrier-protein reductase	fabG	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
k141_4392_49	1391646.AVSU01000032_gene2326	9.71e-116	343.0	COG0331@1|root,COG0331@2|Bacteria,1TPB7@1239|Firmicutes,247UF@186801|Clostridia,25RFG@186804|Peptostreptococcaceae	186801|Clostridia	I	malonyl CoA-acyl carrier protein transacylase	fabD	-	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
k141_4392_50	1286171.EAL2_c11910	4.34e-149	427.0	COG2070@1|root,COG2070@2|Bacteria,1TPC3@1239|Firmicutes,24831@186801|Clostridia,25USN@186806|Eubacteriaceae	186801|Clostridia	S	reductase II	fabK	-	1.3.1.9	ko:K02371	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00083	R04429,R04724,R04955,R04958,R04961,R04966,R04969,R07765	RC00052,RC00076	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	iHN637.CLJU_RS20775	NMO
k141_4392_51	273068.TTE1475	3.75e-151	434.0	COG0332@1|root,COG0332@2|Bacteria,1TP0K@1239|Firmicutes,248V8@186801|Clostridia,42ER1@68295|Thermoanaerobacterales	186801|Clostridia	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
k141_4392_52	1443122.Z958_02635	3.75e-109	328.0	COG0416@1|root,COG0416@2|Bacteria,1TPXS@1239|Firmicutes,247KW@186801|Clostridia,36E96@31979|Clostridiaceae	186801|Clostridia	I	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA	plsX	-	2.3.1.15	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FA_synthesis
k141_4392_53	1121324.CLIT_23c03710	4e-82	248.0	COG1349@1|root,COG1349@2|Bacteria,1V3MJ@1239|Firmicutes,24BT7@186801|Clostridia	186801|Clostridia	K	regulatory protein, DeoR	fapR	-	-	-	-	-	-	-	-	-	-	-	4HBT,HTH_DeoR
k141_4392_54	1443122.Z958_02630	4.26e-18	76.6	COG0333@1|root,COG0333@2|Bacteria,1VEFI@1239|Firmicutes,24QM0@186801|Clostridia,36MII@31979|Clostridiaceae	186801|Clostridia	J	Belongs to the bacterial ribosomal protein bL32 family	rpmF	-	-	ko:K02911	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_L32p
k141_4392_55	324057.Pjdr2_3497	1.55e-11	67.4	COG1399@1|root,COG1399@2|Bacteria,1VEXU@1239|Firmicutes,4HM44@91061|Bacilli,26UF3@186822|Paenibacillaceae	91061|Bacilli	S	metal-binding, possibly nucleic acid-binding protein	-	-	-	ko:K07040	-	-	-	-	ko00000	-	-	-	DUF177
k141_4392_56	1347392.CCEZ01000043_gene503	7.41e-210	588.0	COG0282@1|root,COG0282@2|Bacteria,1TQ22@1239|Firmicutes,248ZM@186801|Clostridia,36EE0@31979|Clostridiaceae	186801|Clostridia	F	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction	ackA	GO:0006082,GO:0006083,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016053,GO:0016999,GO:0017000,GO:0017144,GO:0019413,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:0072330,GO:1901576	2.7.2.1	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00315,R01353	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetate_kinase
k141_4392_57	574087.Acear_1807	1.6e-13	75.1	COG5401@1|root,COG5401@2|Bacteria,1UEAR@1239|Firmicutes,25J65@186801|Clostridia,3WBX7@53433|Halanaerobiales	186801|Clostridia	S	Sporulation and spore germination	-	-	-	-	-	-	-	-	-	-	-	-	Germane
k141_4392_58	97137.C821_00188	6.56e-33	139.0	COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,4HA52@91061|Bacilli,3F45G@33958|Lactobacillaceae	91061|Bacilli	T	Histidine kinase	vicK	-	2.7.13.3	ko:K07652	ko02020,map02020	M00459	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_9
k141_4392_59	1408422.JHYF01000001_gene2677	6.49e-99	294.0	COG0745@1|root,COG0745@2|Bacteria,1TPQG@1239|Firmicutes,248Z4@186801|Clostridia,36W97@31979|Clostridiaceae	186801|Clostridia	T	PFAM response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
k141_4392_60	1121324.CLIT_23c03660	6.48e-226	648.0	COG3276@1|root,COG3276@2|Bacteria,1TPQS@1239|Firmicutes,2484U@186801|Clostridia,25QGF@186804|Peptostreptococcaceae	186801|Clostridia	J	Elongation factor SelB, winged helix	selB	-	-	ko:K03833	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,SelB-wing_2,SelB-wing_3
k141_4392_61	1391646.AVSU01000046_gene1548	1.58e-195	558.0	COG1921@1|root,COG1921@2|Bacteria,1TQT8@1239|Firmicutes,2498U@186801|Clostridia,25R1B@186804|Peptostreptococcaceae	186801|Clostridia	J	Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis	selA	-	2.9.1.1	ko:K01042	ko00450,ko00970,map00450,map00970	-	R08219	RC01246	ko00000,ko00001,ko01000	-	-	-	Se-cys_synth_N,SelA
k141_4392_63	350688.Clos_1738	1.3e-121	360.0	COG0709@1|root,COG0709@2|Bacteria,1TQCJ@1239|Firmicutes,247NS@186801|Clostridia,36DGY@31979|Clostridiaceae	186801|Clostridia	E	Synthesizes selenophosphate from selenide and ATP	selD	-	2.7.9.3	ko:K01008	ko00450,ko01100,map00450,map01100	-	R03595	RC00002,RC02878	ko00000,ko00001,ko01000,ko03016	-	-	-	AIRS,AIRS_C
k141_4392_64	1408823.AXUS01000003_gene531	1.92e-33	127.0	COG1555@1|root,COG1555@2|Bacteria,1VA3W@1239|Firmicutes,24MQF@186801|Clostridia,25RI8@186804|Peptostreptococcaceae	186801|Clostridia	L	Helix-hairpin-helix motif	comEA	-	-	ko:K02237	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	HHH_3,SLBB
k141_4392_65	796940.HMPREF9628_01952	1.8e-111	341.0	COG1686@1|root,COG1686@2|Bacteria,1TQ8M@1239|Firmicutes,2480S@186801|Clostridia,25QXI@186804|Peptostreptococcaceae	186801|Clostridia	M	D-Ala-D-Ala carboxypeptidase 3 (S13) family	dacB	-	3.4.16.4	ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	PBP5_C,Peptidase_S11
k141_4392_66	1121324.CLIT_23c03610	2.8e-45	151.0	COG0593@1|root,COG0593@2|Bacteria,1VAFE@1239|Firmicutes,25E3U@186801|Clostridia	186801|Clostridia	L	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_4392_67	350688.Clos_1741	3.25e-125	365.0	COG1760@1|root,COG1760@2|Bacteria,1TP79@1239|Firmicutes,2480J@186801|Clostridia,36DCQ@31979|Clostridiaceae	186801|Clostridia	E	L-serine dehydratase, iron-sulfur-dependent, alpha subunit	sdaAA	-	4.3.1.17	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	-	R00220,R00590	RC00331,RC02600	ko00000,ko00001,ko01000	-	-	-	SDH_alpha
k141_4392_68	1121324.CLIT_23c03590	1.12e-99	295.0	COG1760@1|root,COG1760@2|Bacteria,1U8TZ@1239|Firmicutes,24AEE@186801|Clostridia	186801|Clostridia	E	L-serine dehydratase, iron-sulfur-dependent, beta subunit	sdaAB	-	4.3.1.17	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	-	R00220,R00590	RC00331,RC02600	ko00000,ko00001,ko01000	-	-	-	ACT,SDH_beta
k141_4392_69	1121324.CLIT_23c03580	3.82e-70	213.0	COG0251@1|root,COG0251@2|Bacteria,1V6HG@1239|Firmicutes,24J8Y@186801|Clostridia,25RF5@186804|Peptostreptococcaceae	186801|Clostridia	J	Endoribonuclease L-PSP	-	-	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP
k141_4392_70	1121324.CLIT_23c03570	3e-185	527.0	COG1171@1|root,COG1171@2|Bacteria,1TP22@1239|Firmicutes,248D5@186801|Clostridia,25QIV@186804|Peptostreptococcaceae	186801|Clostridia	E	threonine	ilvA	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,PALP
k141_4392_71	748727.CLJU_c21680	9.78e-28	106.0	COG0517@1|root,COG0517@2|Bacteria,1VI1R@1239|Firmicutes,24KIA@186801|Clostridia,36JY1@31979|Clostridiaceae	186801|Clostridia	S	CBS domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS
k141_4392_72	1031288.AXAA01000005_gene2107	7.42e-177	505.0	COG0527@1|root,COG0527@2|Bacteria,1TPQJ@1239|Firmicutes,24811@186801|Clostridia,36EUA@31979|Clostridiaceae	186801|Clostridia	E	Belongs to the aspartokinase family	lysC	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT,ACT_7
k141_4392_73	394503.Ccel_3208	5.36e-74	238.0	COG3081@1|root,COG3081@2|Bacteria,1TSR5@1239|Firmicutes,25CG3@186801|Clostridia,36WVH@31979|Clostridiaceae	186801|Clostridia	S	37-kD nucleoid-associated bacterial protein	-	-	-	-	-	-	-	-	-	-	-	-	NA37
k141_4392_74	1121324.CLIT_23c03520	0.0	1266.0	COG0495@1|root,COG0495@2|Bacteria,1TP0Y@1239|Firmicutes,2484Y@186801|Clostridia,25QI2@186804|Peptostreptococcaceae	186801|Clostridia	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	-	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
k141_4392_75	936154.STP_1396	2.87e-29	109.0	COG0799@1|root,COG0799@2|Bacteria,1VA2Z@1239|Firmicutes,4HKEJ@91061|Bacilli	91061|Bacilli	J	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation	rsfS	GO:0003674,GO:0005488,GO:0006417,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0043021,GO:0043023,GO:0044087,GO:0044877,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:0090069,GO:0090071,GO:2000112,GO:2000113	-	ko:K09710	-	-	-	-	ko00000,ko03009	-	-	-	RsfS
k141_4392_76	1121324.CLIT_23c03500	2.02e-112	335.0	COG1316@1|root,COG1316@2|Bacteria,1TR1B@1239|Firmicutes,24AAY@186801|Clostridia	186801|Clostridia	K	TIGRFAM cell envelope-related function transcriptional attenuator	lytR	-	-	-	-	-	-	-	-	-	-	-	LytR_C,LytR_cpsA_psr
k141_4392_77	864565.HMPREF0379_0896	1.12e-49	172.0	COG1057@1|root,COG1713@1|root,COG1057@2|Bacteria,COG1713@2|Bacteria,1V6Y1@1239|Firmicutes,24HN2@186801|Clostridia,25RIB@186804|Peptostreptococcaceae	186801|Clostridia	H	Hydrolase, HD family	nadD	-	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like,HD
k141_4392_78	1151292.QEW_3070	1.83e-77	238.0	COG1057@1|root,COG1057@2|Bacteria,1V3SK@1239|Firmicutes,24JFM@186801|Clostridia,25QZS@186804|Peptostreptococcaceae	186801|Clostridia	H	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	-	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
k141_4392_80	1280689.AUJC01000001_gene2244	2.38e-26	100.0	COG1534@1|root,COG1534@2|Bacteria,1VEGM@1239|Firmicutes,24QZB@186801|Clostridia,36KS2@31979|Clostridiaceae	186801|Clostridia	J	RNA-binding protein	yhbY	-	-	ko:K07574	-	-	-	-	ko00000,ko03009	-	-	-	CRS1_YhbY
k141_4392_81	1511.CLOST_1371	1.5e-205	580.0	COG0536@1|root,COG0536@2|Bacteria,1TPX7@1239|Firmicutes,247SP@186801|Clostridia,25QXG@186804|Peptostreptococcaceae	186801|Clostridia	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	-	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	DUF1967,GTP1_OBG,MMR_HSR1
k141_4392_84	546269.HMPREF0389_00430	3.22e-46	150.0	COG0211@1|root,COG0211@2|Bacteria,1V6HW@1239|Firmicutes,24N3D@186801|Clostridia,25RK1@186804|Peptostreptococcaceae	186801|Clostridia	J	Belongs to the bacterial ribosomal protein bL27 family	rpmA	-	-	ko:K02899	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27
k141_4392_85	1273103.NM10_09088	8.4e-18	79.3	COG2868@1|root,COG2868@2|Bacteria,1TU8A@1239|Firmicutes,4H5SB@909932|Negativicutes	909932|Negativicutes	J	Cysteine protease Prp	-	-	-	ko:K07584	-	-	-	-	ko00000	-	-	-	Peptidase_Prp
k141_4392_86	272563.CD630_11610	4.08e-47	153.0	COG0261@1|root,COG0261@2|Bacteria,1V9YH@1239|Firmicutes,24MRS@186801|Clostridia,25RS2@186804|Peptostreptococcaceae	186801|Clostridia	J	This protein binds to 23S rRNA in the presence of protein L20	rplU	-	-	ko:K02888	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L21p
k141_4392_87	1278306.KB906926_gene1672	5.71e-43	165.0	COG1530@1|root,COG1530@2|Bacteria,378E6@32066|Fusobacteria	32066|Fusobacteria	J	Ribonuclease E/G family	-	-	-	ko:K08301	-	-	-	-	ko00000,ko01000,ko03009,ko03019	-	-	-	RNase_E_G
k141_4392_88	1121289.JHVL01000022_gene1148	4.28e-159	464.0	COG0733@1|root,COG0733@2|Bacteria,1TP6B@1239|Firmicutes,2485D@186801|Clostridia,36DFC@31979|Clostridiaceae	186801|Clostridia	S	Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family	-	-	-	ko:K03308	-	-	-	-	ko00000	2.A.22.4,2.A.22.5	-	-	SNF
k141_4392_89	1304284.L21TH_2085	1.93e-179	512.0	COG1972@1|root,COG1972@2|Bacteria,1TRSK@1239|Firmicutes,249IZ@186801|Clostridia,36FNG@31979|Clostridiaceae	186801|Clostridia	F	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family	-	-	-	ko:K03317	-	-	-	-	ko00000	2.A.41	-	-	Gate,Nucleos_tra2_C,Nucleos_tra2_N
k141_4392_90	1219035.NT2_04_03790	9.54e-10	60.8	COG1664@1|root,COG1664@2|Bacteria,1MZN0@1224|Proteobacteria,2U5DW@28211|Alphaproteobacteria,2K66W@204457|Sphingomonadales	204457|Sphingomonadales	M	Integral membrane protein CcmA involved in cell shape determination	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
k141_4392_91	332101.JIBU02000043_gene1505	9.76e-109	319.0	COG1244@1|root,COG1244@2|Bacteria,1UZ5M@1239|Firmicutes,24AIM@186801|Clostridia,36G6G@31979|Clostridiaceae	186801|Clostridia	S	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_4392_92	37659.JNLN01000001_gene237	3.7e-41	142.0	COG4708@1|root,COG4708@2|Bacteria,1V9YK@1239|Firmicutes,24N9H@186801|Clostridia,36HY4@31979|Clostridiaceae	186801|Clostridia	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	QueT
k141_4392_93	293826.Amet_2638	2.08e-235	659.0	COG5016@1|root,COG5016@2|Bacteria,1VT8P@1239|Firmicutes,247NZ@186801|Clostridia,36UI3@31979|Clostridiaceae	186801|Clostridia	C	carboxyltransferase	pycB	-	4.1.1.3	ko:K01571	ko00620,ko01100,map00620,map01100	-	R00217	RC00040	ko00000,ko00001,ko01000,ko02000	3.B.1.1.1	-	-	HMGL-like,PYC_OADA
k141_4392_94	484770.UFO1_0315	7.4e-97	293.0	COG1737@1|root,COG1737@2|Bacteria,1TP7H@1239|Firmicutes,4H5B4@909932|Negativicutes	909932|Negativicutes	K	Transcriptional regulator, RpiR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_6,SIS
k141_4392_96	717605.Theco_1666	6.42e-18	89.7	COG3103@1|root,COG4193@1|root,COG3103@2|Bacteria,COG4193@2|Bacteria,1V3FK@1239|Firmicutes,4HG9J@91061|Bacilli,26WYR@186822|Paenibacillaceae	91061|Bacilli	GT	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase	-	-	-	-	-	-	-	-	-	-	-	-	Glucosaminidase,SH3_3,SH3_8
k141_4392_97	1304880.JAGB01000003_gene1158	7e-34	128.0	COG5011@1|root,COG5011@2|Bacteria,1V4D0@1239|Firmicutes,249GU@186801|Clostridia	186801|Clostridia	S	Radical SAM-linked protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF2344
k141_4392_98	1151292.QEW_1535	2.34e-307	853.0	COG1032@1|root,COG1032@2|Bacteria,1TR2C@1239|Firmicutes,248HM@186801|Clostridia,25QYC@186804|Peptostreptococcaceae	186801|Clostridia	C	Radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
k141_4392_99	865861.AZSU01000001_gene374	3.59e-74	226.0	COG0225@1|root,COG0225@2|Bacteria,1TQ3E@1239|Firmicutes,247UT@186801|Clostridia,36IWX@31979|Clostridiaceae	186801|Clostridia	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	-	1.8.4.11,1.8.4.12	ko:K07304,ko:K12267	-	-	-	-	ko00000,ko01000	-	-	-	PMSR,SelR
k141_4392_100	986075.CathTA2_1461	1.01e-94	290.0	COG0031@1|root,COG0031@2|Bacteria,1TP30@1239|Firmicutes,4HAMU@91061|Bacilli	91061|Bacilli	E	Belongs to the cysteine synthase cystathionine beta- synthase family	mccA	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004122,GO:0004124,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008284,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016835,GO:0016836,GO:0016846,GO:0019344,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0042127,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0048037,GO:0048518,GO:0048522,GO:0050662,GO:0050789,GO:0050794,GO:0065007,GO:0070279,GO:0071704,GO:0080146,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.5.1.134,2.5.1.47	ko:K01738,ko:K17216	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021,M00609	R00897,R03601,R04859,R10305	RC00020,RC00069,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS02385	PALP
k141_4392_101	555079.Toce_1763	1.02e-62	196.0	COG1854@1|root,COG1854@2|Bacteria,1V1CH@1239|Firmicutes,24G3R@186801|Clostridia,42G14@68295|Thermoanaerobacterales	186801|Clostridia	H	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)	luxS	-	4.4.1.21	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	M00609	R01291	RC00069,RC01929	ko00000,ko00001,ko00002,ko01000	-	-	-	LuxS
k141_2400_3	869209.Tresu_0498	1.29e-58	189.0	COG1396@1|root,COG1917@1|root,COG1396@2|Bacteria,COG1917@2|Bacteria,2J70F@203691|Spirochaetes	203691|Spirochaetes	K	Cupin 2, conserved barrel	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,HTH_3
k141_2400_4	1304885.AUEY01000008_gene2106	1.16e-63	204.0	COG0167@1|root,COG0167@2|Bacteria,1MU7C@1224|Proteobacteria,42M46@68525|delta/epsilon subdivisions,2WJ7G@28221|Deltaproteobacteria,2MIHH@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily	pyrD	GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	1.3.1.14,1.3.5.2	ko:K00254,ko:K02823,ko:K17828	ko00240,ko01100,map00240,map01100	M00051	R01868,R01869	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
k141_402_1	1265505.ATUG01000002_gene1709	1.79e-97	292.0	COG0730@1|root,COG0730@2|Bacteria,1MXNM@1224|Proteobacteria,42KZF@68525|delta/epsilon subdivisions,2WPGW@28221|Deltaproteobacteria,2MI56@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Sulfite exporter TauE/SafE	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
k141_402_2	118163.Ple7327_4066	2.18e-19	90.1	COG0583@1|root,COG0583@2|Bacteria,1G1R9@1117|Cyanobacteria,3VI37@52604|Pleurocapsales	1117|Cyanobacteria	K	Bacterial regulatory helix-turn-helix protein, lysR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
k141_1753_2	1051646.VITU9109_20741	1.87e-135	391.0	COG2126@1|root,COG2126@2|Bacteria,1MXCS@1224|Proteobacteria,1RPCN@1236|Gammaproteobacteria,1XTRC@135623|Vibrionales	135623|Vibrionales	J	COG1226 Kef-type K transport systems	-	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans
k141_1753_4	243277.VC_2038	8.05e-23	107.0	COG0433@1|root,COG2198@1|root,COG0433@2|Bacteria,COG2198@2|Bacteria,1QJH8@1224|Proteobacteria,1THH1@1236|Gammaproteobacteria,1XVSX@135623|Vibrionales	135623|Vibrionales	T	Signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Hpt
k141_1753_5	55601.VANGNB10_cI1849c	1.75e-180	510.0	COG3081@1|root,COG3081@2|Bacteria,1NXJU@1224|Proteobacteria,1RP8N@1236|Gammaproteobacteria,1XU12@135623|Vibrionales	135623|Vibrionales	S	Nucleoid-associated protein	yejK	-	-	ko:K06899	-	-	-	-	ko00000,ko03036	-	-	-	NA37
k141_1753_6	945550.VISI1226_17475	2.92e-27	100.0	COG3082@1|root,COG3082@2|Bacteria,1MZ9I@1224|Proteobacteria,1S8XQ@1236|Gammaproteobacteria,1XYB0@135623|Vibrionales	135623|Vibrionales	S	Belongs to the UPF0352 family	yejL	-	-	ko:K09904	-	-	-	-	ko00000	-	-	-	DUF1414
k141_1753_7	243277.VC_2041	0.0	887.0	COG3083@1|root,COG3083@2|Bacteria,1MX6X@1224|Proteobacteria,1RPAU@1236|Gammaproteobacteria,1XVE8@135623|Vibrionales	135623|Vibrionales	S	hydrolase of alkaline phosphatase superfamily	-	-	-	ko:K07014	-	-	-	-	ko00000	-	-	-	DUF3413,Sulfatase
k141_1753_8	1517681.HW45_06930	4.84e-183	520.0	COG4974@1|root,COG4974@2|Bacteria,1QUDX@1224|Proteobacteria,1T1VB@1236|Gammaproteobacteria,1XX4U@135623|Vibrionales	135623|Vibrionales	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
k141_1753_10	585531.HMPREF0063_10338	1.94e-07	56.2	COG1695@1|root,COG1695@2|Bacteria,2I8DQ@201174|Actinobacteria,4DR4R@85009|Propionibacteriales	201174|Actinobacteria	K	transcriptional regulator PadR family	padR	-	-	-	-	-	-	-	-	-	-	-	PadR,Vir_act_alpha_C
k141_1753_11	1348635.BBJY01000007_gene128	9.58e-45	145.0	2DGT6@1|root,2ZX78@2|Bacteria,1P90M@1224|Proteobacteria,1SUYU@1236|Gammaproteobacteria,1Y1J4@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_1753_12	1348635.BBJY01000007_gene129	6.33e-46	149.0	2B58X@1|root,31NY3@2|Bacteria,1QKMH@1224|Proteobacteria,1TIRZ@1236|Gammaproteobacteria,1XZJ2@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_1753_13	1348635.BBJY01000007_gene130	5.29e-38	129.0	2DRJA@1|root,33C0M@2|Bacteria	2|Bacteria	S	Domain of Unknown Function with PDB structure (DUF3850)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3850
k141_1753_15	1278307.KB906995_gene2982	9.2e-60	191.0	COG0847@1|root,COG0847@2|Bacteria,1R9YS@1224|Proteobacteria,1S23K@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	3' exoribonuclease, RNase T-like	-	-	-	ko:K10906	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DUF5051,Exonuc_VIII
k141_1753_16	1348635.BBJY01000007_gene133	0.0	1692.0	COG0358@1|root,COG0358@2|Bacteria,1MWQW@1224|Proteobacteria,1TIXC@1236|Gammaproteobacteria,1XZX0@135623|Vibrionales	135623|Vibrionales	L	Toprim domain	-	-	-	-	-	-	-	-	-	-	-	-	Toprim_3
k141_1753_17	1348635.BBJY01000007_gene134	1.88e-28	103.0	29HXD@1|root,304UF@2|Bacteria,1QMKF@1224|Proteobacteria,1TJW0@1236|Gammaproteobacteria,1Y1RT@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_1753_18	1348635.BBJY01000007_gene135	1.03e-45	149.0	2AXQH@1|root,31PRA@2|Bacteria,1QMEH@1224|Proteobacteria,1TJPF@1236|Gammaproteobacteria,1Y1H4@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_1753_20	1348635.BBJY01000007_gene138	4.09e-137	391.0	COG4974@1|root,COG4974@2|Bacteria,1PBXC@1224|Proteobacteria,1TIVC@1236|Gammaproteobacteria,1XZS0@135623|Vibrionales	135623|Vibrionales	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
k141_1753_21	1348635.BBJY01000007_gene139	1.27e-81	244.0	2AKWB@1|root,31BPQ@2|Bacteria,1Q7JR@1224|Proteobacteria,1STNH@1236|Gammaproteobacteria,1Y14E@135623|Vibrionales	135623|Vibrionales	S	Phage regulatory protein CII (CP76)	-	-	-	-	-	-	-	-	-	-	-	-	Phage_CP76
k141_1753_22	1517681.HW45_07000	9.28e-14	65.9	2AXSV@1|root,31PTU@2|Bacteria,1QMGS@1224|Proteobacteria,1TJS4@1236|Gammaproteobacteria,1Y1KY@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_1753_23	1348635.BBJY01000007_gene141	8.57e-55	179.0	2AXDX@1|root,31PD9@2|Bacteria,1QM3D@1224|Proteobacteria,1TJAV@1236|Gammaproteobacteria,1Y0X8@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_3448_1	517418.Ctha_1441	1.88e-60	190.0	COG1584@1|root,COG1584@2|Bacteria	2|Bacteria	S	GPR1 FUN34 yaaH family protein	yaaH	GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006835,GO:0006846,GO:0006855,GO:0008028,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015077,GO:0015078,GO:0015123,GO:0015238,GO:0015291,GO:0015293,GO:0015294,GO:0015295,GO:0015318,GO:0015355,GO:0015360,GO:0015672,GO:0015711,GO:0015718,GO:0015740,GO:0015744,GO:0015849,GO:0015893,GO:0016020,GO:0022804,GO:0022857,GO:0022890,GO:0034220,GO:0035433,GO:0042221,GO:0042493,GO:0042891,GO:0042895,GO:0043893,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071422,GO:0071702,GO:0071944,GO:0098655,GO:0098656,GO:0098660,GO:0098662,GO:1902600,GO:1903825,GO:1905039	-	ko:K07034	-	-	-	-	ko00000	-	-	-	Grp1_Fun34_YaaH
k141_3448_2	1123355.JHYO01000026_gene226	3.01e-37	135.0	COG3437@1|root,COG3437@2|Bacteria,1MUB8@1224|Proteobacteria,2TY3Z@28211|Alphaproteobacteria,3718N@31993|Methylocystaceae	28211|Alphaproteobacteria	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	HD,HD_5,Response_reg
k141_83_1	1120953.AUBH01000002_gene1534	2.53e-116	347.0	COG0247@1|root,COG0247@2|Bacteria,1R033@1224|Proteobacteria,1T4MK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_22
k141_83_2	511062.GU3_11745	1.37e-129	375.0	COG0543@1|root,COG0543@2|Bacteria,1R6QZ@1224|Proteobacteria,1RNK9@1236|Gammaproteobacteria,1Y61G@135624|Aeromonadales	135624|Aeromonadales	C	Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B	-	-	-	ko:K16951	ko00920,ko01120,map00920,map01120	-	R00858,R10146	RC00065	ko00000,ko00001	-	-	-	DHODB_Fe-S_bind,NAD_binding_1
k141_83_3	1120953.AUBH01000002_gene1536	2.3e-107	318.0	COG1941@1|root,COG1941@2|Bacteria,1NS0E@1224|Proteobacteria,1RW0G@1236|Gammaproteobacteria,466Y9@72275|Alteromonadaceae	1236|Gammaproteobacteria	C	NADH ubiquinone oxidoreductase, 20 Kd subunit	hoxY	-	-	-	-	-	-	-	-	-	-	-	Oxidored_q6
k141_83_4	511062.GU3_11735	4.9e-176	506.0	COG3259@1|root,COG3259@2|Bacteria,1QUQ7@1224|Proteobacteria,1T20U@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	PFAM Nickel-dependent hydrogenase, large subunit	hoxH	-	-	-	-	-	-	-	-	-	-	-	NiFeSe_Hases
k141_83_6	1187848.AJYQ01000156_gene3905	1.76e-185	539.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMV2@1236|Gammaproteobacteria,1XSAN@135623|Vibrionales	135623|Vibrionales	T	methyl-accepting chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal,sCache_2
k141_83_7	675812.VHA_002522	1.96e-43	153.0	COG2188@1|root,COG2188@2|Bacteria,1R4PN@1224|Proteobacteria,1RQ87@1236|Gammaproteobacteria,1XT3H@135623|Vibrionales	135623|Vibrionales	K	COG2188 Transcriptional regulators	phnR	-	-	-	-	-	-	-	-	-	-	-	GntR,UTRA
k141_4452_1	1265505.ATUG01000001_gene4163	3.43e-120	356.0	COG1180@1|root,COG1180@2|Bacteria,1NQC1@1224|Proteobacteria,42N7U@68525|delta/epsilon subdivisions,2WJ81@28221|Deltaproteobacteria,2MI27@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM Radical SAM	-	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
k141_4452_2	933262.AXAM01000017_gene3119	5.32e-87	268.0	COG0382@1|root,COG0382@2|Bacteria,1MV4Q@1224|Proteobacteria,42MXH@68525|delta/epsilon subdivisions,2WK8E@28221|Deltaproteobacteria,2MITG@213118|Desulfobacterales	28221|Deltaproteobacteria	H	4-hydroxybenzoate polyprenyltransferase	ubiA	-	2.5.1.39	ko:K03179	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R05000,R05615	RC00209,RC02895	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
k141_4452_3	1121035.AUCH01000008_gene1079	1.01e-45	157.0	COG0163@1|root,COG0163@2|Bacteria,1RA0P@1224|Proteobacteria,2VIWQ@28216|Betaproteobacteria,2KVP4@206389|Rhodocyclales	206389|Rhodocyclales	H	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN	ubiX	-	2.5.1.129	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	M00117	R01238,R02952,R03367,R04985,R04986,R11225	RC00391,RC00814,RC03392	ko00000,ko00001,ko00002,ko01000	-	-	-	Flavoprotein
k141_84_1	1499680.CCFE01000018_gene1194	2.04e-09	55.8	2EG8N@1|root,33A0G@2|Bacteria,1VMHK@1239|Firmicutes,4HSIH@91061|Bacilli,1ZJWT@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_2402_1	177437.HRM2_37190	8.24e-128	372.0	COG1868@1|root,COG1868@2|Bacteria,1MX01@1224|Proteobacteria,42N2Y@68525|delta/epsilon subdivisions,2WIS2@28221|Deltaproteobacteria,2MI59@213118|Desulfobacterales	28221|Deltaproteobacteria	N	flagellar motor switch protein FliM	fliM	-	-	ko:K02416	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliM,FliMN_C
k141_3451_1	717774.Marme_3843	5.82e-23	99.8	COG0697@1|root,COG0697@2|Bacteria,1P3V0@1224|Proteobacteria,1S25I@1236|Gammaproteobacteria,1XNDW@135619|Oceanospirillales	135619|Oceanospirillales	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
k141_3101_1	1219065.VPR01S_35_00130	9.8e-100	291.0	2EV63@1|root,33NKW@2|Bacteria,1NPVR@1224|Proteobacteria,1SHV1@1236|Gammaproteobacteria,1Y07U@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_3101_2	318167.Sfri_1662	1.58e-223	619.0	COG3547@1|root,COG3547@2|Bacteria,1NGR7@1224|Proteobacteria,1RMF9@1236|Gammaproteobacteria,2QC8A@267890|Shewanellaceae	1236|Gammaproteobacteria	L	PFAM transposase IS116 IS110 IS902 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k141_85_1	1121405.dsmv_0606	2.3e-173	497.0	COG0001@1|root,COG0001@2|Bacteria,1MUY5@1224|Proteobacteria,42MBF@68525|delta/epsilon subdivisions,2WJQ2@28221|Deltaproteobacteria,2MIIV@213118|Desulfobacterales	28221|Deltaproteobacteria	H	PFAM aminotransferase class-III	hemL	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
k141_85_2	1121405.dsmv_2877	5.72e-05	45.1	COG1859@1|root,COG1859@2|Bacteria,1RD8B@1224|Proteobacteria,42TK9@68525|delta/epsilon subdivisions,2WQVQ@28221|Deltaproteobacteria,2MMDE@213118|Desulfobacterales	28221|Deltaproteobacteria	J	PFAM phosphotransferase KptA Tpt1	-	-	-	ko:K07559	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PTS_2-RNA
k141_403_1	1265505.ATUG01000002_gene1501	1.05e-47	155.0	COG3370@1|root,COG3370@2|Bacteria,1N27G@1224|Proteobacteria,42TID@68525|delta/epsilon subdivisions,2X5QM@28221|Deltaproteobacteria,2MM1R@213118|Desulfobacterales	28221|Deltaproteobacteria	S	DsrE/DsrF-like family	-	-	-	-	-	-	-	-	-	-	-	-	DrsE
k141_403_2	595494.Tola_1404	2.19e-39	137.0	COG1533@1|root,COG1533@2|Bacteria,1MW0H@1224|Proteobacteria,1RQNF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
k141_403_3	32057.KB217483_gene9669	4.03e-22	103.0	COG2207@1|root,COG2207@2|Bacteria,1G55X@1117|Cyanobacteria,1HTUX@1161|Nostocales	1117|Cyanobacteria	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
k141_403_5	439235.Dalk_4324	8.22e-63	218.0	COG4206@1|root,COG4206@2|Bacteria,1QUJF@1224|Proteobacteria,43BJH@68525|delta/epsilon subdivisions,2WQ7X@28221|Deltaproteobacteria,2MKST@213118|Desulfobacterales	28221|Deltaproteobacteria	H	TonB dependent receptor	-	-	-	ko:K02014,ko:K16092	-	-	-	-	ko00000,ko02000	1.B.14,1.B.14.3	-	-	Plug,TonB_dep_Rec
k141_1754_1	498211.CJA_2520	4.86e-181	589.0	COG1022@1|root,COG5184@1|root,COG5276@1|root,COG1022@2|Bacteria,COG5184@2|Bacteria,COG5276@2|Bacteria,1PG4J@1224|Proteobacteria,1RWXR@1236|Gammaproteobacteria,1FIEH@10|Cellvibrio	1236|Gammaproteobacteria	DZ	Regulator of chromosome condensation (RCC1) repeat	-	-	-	-	-	-	-	-	-	-	-	-	RCC1
k141_86_1	879212.DespoDRAFT_02032	2.75e-29	115.0	COG0728@1|root,COG0728@2|Bacteria,1MUH0@1224|Proteobacteria,42M28@68525|delta/epsilon subdivisions,2WJPF@28221|Deltaproteobacteria,2MHXP@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane	murJ	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
k141_3453_1	156889.Mmc1_1148	1.63e-30	127.0	COG2199@1|root,COG4564@1|root,COG3706@2|Bacteria,COG4564@2|Bacteria,1R7HC@1224|Proteobacteria,2TQQM@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	response regulator containing a CheY-like receiver domain and a GGDEF domain	-	-	2.7.7.65	ko:K13069	-	-	R08057	-	ko00000,ko01000	-	-	-	CZB,GGDEF
k141_405_1	290315.Clim_1915	1.1e-78	254.0	COG1132@1|root,COG1132@2|Bacteria,1FD6W@1090|Chlorobi	2|Bacteria	P	PFAM ABC transporter transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
k141_406_1	1121403.AUCV01000002_gene562	7.01e-28	115.0	COG4313@1|root,COG4313@2|Bacteria,1R58D@1224|Proteobacteria,42SAW@68525|delta/epsilon subdivisions,2WP5F@28221|Deltaproteobacteria,2MKGF@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Putative MetA-pathway of phenol degradation	-	-	-	-	-	-	-	-	-	-	-	-	Phenol_MetA_deg
k141_3454_1	574087.Acear_1837	1.03e-188	550.0	COG3829@1|root,COG3829@2|Bacteria,1TP0E@1239|Firmicutes,247MB@186801|Clostridia,3WBEI@53433|Halanaerobiales	186801|Clostridia	K	COGs COG3829 Transcriptional regulator containing PAS AAA-type ATPase and DNA-binding domains	-	-	-	-	-	-	-	-	-	-	-	-	CBS,HTH_12,HTH_8,PAS,Sigma54_activat
k141_4453_1	1219072.VHA01S_020_00310	2.05e-11	63.2	COG3623@1|root,COG3623@2|Bacteria,1MWTD@1224|Proteobacteria,1RPT6@1236|Gammaproteobacteria,1XVJF@135623|Vibrionales	135623|Vibrionales	G	3-epimerase	sgbU	-	5.1.3.22	ko:K03079	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	M00550	R03244	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	AP_endonuc_2
k141_4453_2	672.VV93_v1c44800	2.36e-74	225.0	2AW3C@1|root,31MY7@2|Bacteria,1QJQ8@1224|Proteobacteria,1THRD@1236|Gammaproteobacteria,1XXA6@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_4453_3	1232446.BAIE02000085_gene1141	7.08e-309	845.0	COG2723@1|root,COG2723@2|Bacteria,1TP19@1239|Firmicutes,2485V@186801|Clostridia	186801|Clostridia	G	Belongs to the glycosyl hydrolase 1 family	-	-	3.2.1.86	ko:K01223	ko00010,ko00500,map00010,map00500	-	R00839,R05133,R05134	RC00049,RC00171,RC00714	ko00000,ko00001,ko01000	-	GT1	-	Glyco_hydro_1
k141_4453_4	911008.GLAD_01512	3.35e-99	303.0	COG1609@1|root,COG1609@2|Bacteria,1N4ND@1224|Proteobacteria,1RNR5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	Transcriptional regulator	ascG	-	-	-	-	-	-	-	-	-	-	-	LacI,Peripla_BP_3
k141_4453_5	1283284.AZUK01000001_gene1337	1.41e-45	149.0	COG1447@1|root,COG1447@2|Bacteria,1N0T8@1224|Proteobacteria,1S9TV@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	PFAM phosphotransferase system PTS, lactose cellobiose-specific IIA subunit	bglI	-	2.7.1.196,2.7.1.205	ko:K02759	ko00500,ko02060,map00500,map02060	M00275	R11170,R11172	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.3.2	-	-	PTS_IIA
k141_4453_6	1073999.BN137_501	2.27e-25	105.0	COG1455@1|root,COG1455@2|Bacteria,1MXAG@1224|Proteobacteria,1RQGX@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane	bglF	-	-	ko:K02761	ko00500,ko02060,map00500,map02060	M00275	R11170,R11172	RC00017,RC03206	ko00000,ko00001,ko00002,ko02000	4.A.3.2	-	-	PTS_EIIC
k141_3455_1	65393.PCC7424_5660	3.61e-07	53.5	COG5433@1|root,COG5433@2|Bacteria,1G0VN@1117|Cyanobacteria,3KHBS@43988|Cyanothece	1117|Cyanobacteria	L	PFAM transposase IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_assoc
k141_2403_1	388413.ALPR1_20088	5.26e-175	495.0	COG1902@1|root,COG1902@2|Bacteria,4NF98@976|Bacteroidetes,47M7J@768503|Cytophagia	976|Bacteroidetes	C	PFAM NADH flavin oxidoreductase NADH oxidase	nemA	-	-	ko:K10680	ko00633,ko01120,map00633,map01120	-	R08014,R08017,R08042	RC00250	ko00000,ko00001,ko01000	-	-	-	Oxidored_FMN
k141_2403_2	661367.LLO_0643	1.93e-230	655.0	COG3410@1|root,COG3410@2|Bacteria,1PRQ3@1224|Proteobacteria,1RR13@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Uncharacterized conserved protein (DUF2075)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2075
k141_4454_1	338966.Ppro_1941	7.23e-66	211.0	COG2834@1|root,COG2834@2|Bacteria,1MXW0@1224|Proteobacteria,42QPE@68525|delta/epsilon subdivisions,2WN39@28221|Deltaproteobacteria,43VVR@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Outer membrane lipoprotein-sorting protein	-	-	-	-	-	-	-	-	-	-	-	-	LolA_like
k141_4454_2	1121396.KB893103_gene1771	9.63e-51	181.0	COG1033@1|root,COG1033@2|Bacteria,1MUE1@1224|Proteobacteria,42ME2@68525|delta/epsilon subdivisions,2WJRI@28221|Deltaproteobacteria,2MMR2@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Sterol-sensing domain of SREBP cleavage-activation	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	GGDEF,LolA_like,MMPL,cNMP_binding
k141_408_2	316275.VSAL_I0820	1.39e-62	203.0	COG3385@1|root,COG3385@2|Bacteria,1R55Y@1224|Proteobacteria,1RRSD@1236|Gammaproteobacteria,1XVIP@135623|Vibrionales	135623|Vibrionales	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
k141_408_3	1280001.BAOA01000078_gene3139	6.73e-42	150.0	COG3604@1|root,COG3604@2|Bacteria,1QTT3@1224|Proteobacteria,1T1G7@1236|Gammaproteobacteria,1XSRB@135623|Vibrionales	135623|Vibrionales	K	COG3604 Transcriptional regulator containing GAF, AAA-type ATPase, and DNA binding domains	-	-	-	ko:K12266	ko05132,map05132	-	-	-	ko00000,ko00001,ko03000	-	-	-	GAF,HTH_8,Sigma54_activat
k141_87_1	298386.PBPRA2816	1.3e-57	187.0	COG2755@1|root,COG2755@2|Bacteria,1RCXZ@1224|Proteobacteria,1S3QU@1236|Gammaproteobacteria,1XVT0@135623|Vibrionales	135623|Vibrionales	E	COG2755 Lysophospholipase L1 and related esterases	tesA	-	3.1.1.5	ko:K10804	ko01040,map01040	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	Lipase_GDSL_2
k141_115_2	96561.Dole_0132	1.58e-44	153.0	COG0494@1|root,COG0494@2|Bacteria,1Q0FU@1224|Proteobacteria,42S2C@68525|delta/epsilon subdivisions,2WNP0@28221|Deltaproteobacteria,2MJSY@213118|Desulfobacterales	28221|Deltaproteobacteria	L	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
k141_115_3	694427.Palpr_2708	2.87e-09	61.6	COG1331@1|root,COG1331@2|Bacteria,4NMU8@976|Bacteroidetes,2G2XF@200643|Bacteroidia,231K3@171551|Porphyromonadaceae	976|Bacteroidetes	O	PFAM Thioredoxin domain-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_7
k141_117_1	1499683.CCFF01000017_gene2717	1.51e-41	155.0	COG0608@1|root,COG0608@2|Bacteria,1TPXE@1239|Firmicutes,247NU@186801|Clostridia,36EVY@31979|Clostridiaceae	186801|Clostridia	L	Single-stranded-DNA-specific exonuclease RecJ	recJ	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
k141_119_1	1304284.L21TH_2537	1.09e-53	171.0	COG3411@1|root,COG3411@2|Bacteria,1V6DT@1239|Firmicutes,24M31@186801|Clostridia,36JIG@31979|Clostridiaceae	186801|Clostridia	C	Ferredoxin	-	-	1.12.1.3	ko:K17992	-	-	-	-	ko00000,ko01000	-	-	-	2Fe-2S_thioredx
k141_119_2	1304284.L21TH_2536	8e-29	114.0	COG1894@1|root,COG1894@2|Bacteria,1TQB0@1239|Firmicutes,2483E@186801|Clostridia,36EMP@31979|Clostridiaceae	186801|Clostridia	C	Respiratory-chain NADH dehydrogenase domain 51 kDa subunit	hymB	-	1.12.1.3,1.17.1.11,1.6.5.3	ko:K00335,ko:K18331,ko:K22339	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx,Complex1_51K,Fer4,NADH_4Fe-4S,SLBB
k141_425_1	29495.EA26_15550	1.85e-240	670.0	COG0733@1|root,COG0733@2|Bacteria,1MUZJ@1224|Proteobacteria,1RPCT@1236|Gammaproteobacteria,1XT5X@135623|Vibrionales	135623|Vibrionales	S	COG0733 Na -dependent transporters of the SNF family	yocR	-	-	ko:K03308	-	-	-	-	ko00000	2.A.22.4,2.A.22.5	-	-	SNF
k141_425_2	1517681.HW45_16805	7.35e-100	296.0	COG0564@1|root,COG0564@2|Bacteria,1RDAG@1224|Proteobacteria,1S406@1236|Gammaproteobacteria,1XVCV@135623|Vibrionales	135623|Vibrionales	J	COG0564 Pseudouridylate synthases, 23S RNA-specific	-	-	5.4.99.28,5.4.99.29	ko:K06177	-	-	-	-	ko00000,ko01000,ko03009,ko03016	-	-	-	PseudoU_synth_2
k141_425_3	1219076.N646_0234	8.62e-143	412.0	COG1092@1|root,COG1092@2|Bacteria,1PUHQ@1224|Proteobacteria,1RN8N@1236|Gammaproteobacteria,1XTCF@135623|Vibrionales	135623|Vibrionales	J	Belongs to the methyltransferase superfamily	-	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
k141_3787_2	1219080.VEZ01S_21_00540	2.32e-94	280.0	COG1584@1|root,COG1584@2|Bacteria,1N3HP@1224|Proteobacteria,1RMRK@1236|Gammaproteobacteria,1XTVE@135623|Vibrionales	135623|Vibrionales	S	GPR1/FUN34/yaaH family	yaaH	-	-	ko:K07034	-	-	-	-	ko00000	-	-	-	Grp1_Fun34_YaaH
k141_3787_3	29495.EA26_03950	6.73e-118	339.0	COG1584@1|root,COG1584@2|Bacteria,1N3HP@1224|Proteobacteria,1RMRK@1236|Gammaproteobacteria,1XTVE@135623|Vibrionales	135623|Vibrionales	S	GPR1/FUN34/yaaH family	yaaH	-	-	ko:K07034	-	-	-	-	ko00000	-	-	-	Grp1_Fun34_YaaH
k141_3787_4	243277.VC_0784	6.29e-297	819.0	COG1115@1|root,COG1115@2|Bacteria,1MUI3@1224|Proteobacteria,1RMNF@1236|Gammaproteobacteria,1XU2Z@135623|Vibrionales	135623|Vibrionales	U	COG1115 Na alanine symporter	-	-	-	ko:K03310	-	-	-	-	ko00000	2.A.25	-	-	Na_Ala_symp
k141_120_1	1265505.ATUG01000001_gene4788	5.31e-37	139.0	COG4591@1|root,COG4591@2|Bacteria,1R4Q2@1224|Proteobacteria,42N3Y@68525|delta/epsilon subdivisions,2WJFS@28221|Deltaproteobacteria,2MJEA@213118|Desulfobacterales	28221|Deltaproteobacteria	M	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
k141_120_2	1232437.KL661988_gene227	1.31e-115	349.0	COG4591@1|root,COG4591@2|Bacteria,1R4Q2@1224|Proteobacteria,42QGA@68525|delta/epsilon subdivisions,2WJYS@28221|Deltaproteobacteria,2MI4W@213118|Desulfobacterales	28221|Deltaproteobacteria	M	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
k141_426_1	1051646.VITU9109_07583	3.69e-31	110.0	2AWFJ@1|root,31NBT@2|Bacteria,1QK2U@1224|Proteobacteria,1TI5K@1236|Gammaproteobacteria,1XYFB@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_426_2	945550.VISI1226_03615	2.92e-88	261.0	COG1607@1|root,COG1607@2|Bacteria,1RAEQ@1224|Proteobacteria,1S313@1236|Gammaproteobacteria,1XTW2@135623|Vibrionales	135623|Vibrionales	I	Acyl-CoA hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
k141_426_3	1348635.BBJY01000001_gene2583	1.42e-46	156.0	COG4976@1|root,COG4976@2|Bacteria,1QV99@1224|Proteobacteria,1T2AQ@1236|Gammaproteobacteria,1Y346@135623|Vibrionales	135623|Vibrionales	S	DREV methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
k141_121_2	1265845.PWEIH_15433	3.87e-28	112.0	COG5444@1|root,COG5444@2|Bacteria	2|Bacteria	UW	nuclease activity	-	-	-	-	-	-	-	-	-	-	-	-	Colicin-DNase,Endonuclea_NS_2,LXG
k141_1215_1	391587.KAOT1_07983	4.5e-50	166.0	2DC7W@1|root,2ZD7C@2|Bacteria,4NMMW@976|Bacteroidetes,1I1HS@117743|Flavobacteriia	976|Bacteroidetes	S	Chalcone isomerase-like	-	-	-	-	-	-	-	-	-	-	-	-	Chalcone_3
k141_4918_1	880073.Calab_3328	2.63e-13	77.0	COG1807@1|root,COG1807@2|Bacteria,2NPZC@2323|unclassified Bacteria	2|Bacteria	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	PMT_2
k141_2484_2	1121403.AUCV01000015_gene4724	2.13e-71	226.0	COG1914@1|root,COG1914@2|Bacteria,1MW6X@1224|Proteobacteria,42RRV@68525|delta/epsilon subdivisions,2WNKH@28221|Deltaproteobacteria,2MJB4@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Natural resistance-associated macrophage protein	-	-	-	-	-	-	-	-	-	-	-	-	Nramp
k141_1887_1	998088.B565_3949	3.39e-35	143.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,1Y5G5@135624|Aeromonadales	135624|Aeromonadales	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal,dCache_3
k141_1887_2	1348635.BBJY01000005_gene3326	4.08e-223	617.0	COG0115@1|root,COG0115@2|Bacteria,1MVB0@1224|Proteobacteria,1RP6Z@1236|Gammaproteobacteria,1XUBQ@135623|Vibrionales	135623|Vibrionales	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
k141_1887_3	465817.ETA_14440	6.6e-78	243.0	COG0697@1|root,COG0697@2|Bacteria,1MVKG@1224|Proteobacteria,1S2WV@1236|Gammaproteobacteria,3X50Y@551|Erwinia	1236|Gammaproteobacteria	EG	Drug Metabolite Transporter (DMT) Superfamily	eamA	-	-	ko:K15268	-	-	-	-	ko00000,ko02000	2.A.7.3.2	-	-	EamA
k141_4919_1	626887.J057_18140	3.54e-60	197.0	COG0566@1|root,COG0566@2|Bacteria,1MWBE@1224|Proteobacteria,1RMPR@1236|Gammaproteobacteria,466RK@72275|Alteromonadaceae	1236|Gammaproteobacteria	J	Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA	trmH	GO:0001510,GO:0002128,GO:0002938,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008175,GO:0008757,GO:0009020,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0106050,GO:0140098,GO:0140101,GO:1901360	2.1.1.34	ko:K00556	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylas_C,SpoU_methylase
k141_3889_1	675817.VDA_002414	2.03e-302	830.0	COG3666@1|root,COG3666@2|Bacteria,1N3QR@1224|Proteobacteria,1RR2W@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	COG3666 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_6,DUF772
k141_3889_2	223926.28806812	7.03e-62	189.0	COG4115@1|root,COG4115@2|Bacteria,1MZBP@1224|Proteobacteria,1S99Z@1236|Gammaproteobacteria,1XY05@135623|Vibrionales	135623|Vibrionales	S	YoeB-like toxin of bacterial type II toxin-antitoxin system	yoeB	-	-	ko:K19158	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	YoeB_toxin
k141_3889_3	223926.28806813	3.61e-51	162.0	COG2161@1|root,COG2161@2|Bacteria,1N6X6@1224|Proteobacteria,1SDQ0@1236|Gammaproteobacteria,1Y2ET@135623|Vibrionales	135623|Vibrionales	D	Antitoxin component of a toxin-antitoxin (TA) module	yefM	-	-	ko:K19159	-	-	-	-	ko00000,ko02048	-	-	-	PhdYeFM_antitox
k141_3889_4	87626.PTD2_22282	1.07e-268	740.0	COG3344@1|root,COG3344@2|Bacteria,1MVI1@1224|Proteobacteria,1RQP7@1236|Gammaproteobacteria,2Q3E0@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	L	COG3344 Retron-type reverse transcriptase	-	-	-	-	-	-	-	-	-	-	-	-	GIIM,RVT_1
k141_3210_1	1304885.AUEY01000025_gene2750	8.88e-184	529.0	COG1160@1|root,COG1160@2|Bacteria,1MU9S@1224|Proteobacteria,42M3N@68525|delta/epsilon subdivisions,2WISS@28221|Deltaproteobacteria,2MHQH@213118|Desulfobacterales	28221|Deltaproteobacteria	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	-	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
k141_3210_2	96561.Dole_2133	5.89e-166	481.0	COG2256@1|root,COG2256@2|Bacteria,1MUVS@1224|Proteobacteria,42M9X@68525|delta/epsilon subdivisions,2WJ7E@28221|Deltaproteobacteria,2MIA5@213118|Desulfobacterales	28221|Deltaproteobacteria	L	AAA ATPase	rarA	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA,AAA_assoc_2,MgsA_C,RuvB_N
k141_1218_1	1232437.KL662006_gene4442	8.53e-50	167.0	COG3359@1|root,COG3359@2|Bacteria,1R6A2@1224|Proteobacteria,42MVN@68525|delta/epsilon subdivisions,2WK0C@28221|Deltaproteobacteria,2MJ33@213118|Desulfobacterales	28221|Deltaproteobacteria	L	RNase_H superfamily	-	-	-	ko:K07502	-	-	-	-	ko00000	-	-	-	RNase_H_2
k141_1888_1	1283299.AUKG01000002_gene3656	8.66e-10	65.9	COG3437@1|root,COG3437@2|Bacteria,2I49F@201174|Actinobacteria,4CSM0@84995|Rubrobacteria	84995|Rubrobacteria	KT	CHASE2	-	-	-	-	-	-	-	-	-	-	-	-	CHASE2,HD
k141_2180_2	675812.VHA_003196	2.04e-220	616.0	COG0508@1|root,COG0508@2|Bacteria,1MUJD@1224|Proteobacteria,1RME0@1236|Gammaproteobacteria,1XTKP@135623|Vibrionales	135623|Vibrionales	C	The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)	sucB	-	2.3.1.61	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R02570,R02571,R08549	RC00004,RC02727,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
k141_2180_3	1248232.BANQ01000068_gene2198	7.57e-238	659.0	COG0045@1|root,COG0045@2|Bacteria,1MVCE@1224|Proteobacteria,1RMSU@1236|Gammaproteobacteria,1XTU2@135623|Vibrionales	135623|Vibrionales	F	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit	sucC	GO:0003674,GO:0003824,GO:0004774,GO:0004775,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016874,GO:0016877,GO:0016878,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350	6.2.1.5	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,Ligase_CoA
k141_2180_5	701176.VIBRN418_13256	2.05e-130	377.0	COG1108@1|root,COG1108@2|Bacteria,1MVC2@1224|Proteobacteria,1RPYF@1236|Gammaproteobacteria,1XTAW@135623|Vibrionales	135623|Vibrionales	P	COG1108 ABC-type Mn2 Zn2 transport systems, permease components	znuB	-	-	ko:K09816	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ABC-3
k141_2180_6	675813.VIB_000813	5.46e-132	380.0	COG1121@1|root,COG1121@2|Bacteria,1MUDW@1224|Proteobacteria,1RPJT@1236|Gammaproteobacteria,1XTI4@135623|Vibrionales	135623|Vibrionales	P	Part of the ABC transporter complex ZnuABC involved in zinc import. Responsible for energy coupling to the transport system	znuC	GO:0000041,GO:0003674,GO:0003824,GO:0005215,GO:0005385,GO:0006810,GO:0006811,GO:0006812,GO:0006829,GO:0008150,GO:0008324,GO:0015075,GO:0015318,GO:0015399,GO:0015405,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0042623,GO:0042626,GO:0043492,GO:0046873,GO:0046915,GO:0051179,GO:0051234,GO:0055085,GO:0070838,GO:0071577,GO:0072509,GO:0072511,GO:0098655,GO:0098660,GO:0098662	-	ko:K09817	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ABC_tran
k141_2180_7	675813.VIB_000814	1.66e-70	224.0	COG4531@1|root,COG4531@2|Bacteria,1QTTI@1224|Proteobacteria,1RMRJ@1236|Gammaproteobacteria,1XT4D@135623|Vibrionales	135623|Vibrionales	P	COG4531 ABC-type Zn2 transport system, periplasmic component surface adhesin	znuA	-	-	ko:K09815	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ZnuA
k141_3890_1	1232452.BAIB02000003_gene472	3.47e-75	247.0	COG1012@1|root,COG1454@1|root,COG1012@2|Bacteria,COG1454@2|Bacteria,1TPB4@1239|Firmicutes,247IQ@186801|Clostridia,2686V@186813|unclassified Clostridiales	186801|Clostridia	C	belongs to the iron- containing alcohol dehydrogenase family	adhE	-	1.1.1.1,1.2.1.10	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	-	R00228,R00623,R00754,R01172,R04880,R05233,R05234,R06917,R06927	RC00004,RC00050,RC00088,RC00099,RC00116,RC00184,RC00649,RC01195	ko00000,ko00001,ko01000	-	-	-	Aldedh,Fe-ADH
k141_4920_1	941449.dsx2_0364	2.59e-50	181.0	COG0845@1|root,COG0845@2|Bacteria,1MVAS@1224|Proteobacteria,42PKU@68525|delta/epsilon subdivisions,2WM5K@28221|Deltaproteobacteria,2M9X5@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K07798,ko:K15727	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4,8.A.1,8.A.1.2.1	-	-	DUF3347,HlyD_D23
k141_786_80	1122207.MUS1_01505	7.99e-114	337.0	COG3220@1|root,COG3220@2|Bacteria,1MURE@1224|Proteobacteria,1RQ9H@1236|Gammaproteobacteria,1XJ41@135619|Oceanospirillales	135619|Oceanospirillales	S	Protein of unknown function (DUF692)	-	-	-	ko:K09930	-	-	-	-	ko00000	-	-	-	DUF692
k141_786_81	1279015.KB908462_gene1905	4.44e-34	119.0	COG5572@1|root,COG5572@2|Bacteria,1MZ6Q@1224|Proteobacteria,1S9Q2@1236|Gammaproteobacteria,1Y6KN@135624|Aeromonadales	135624|Aeromonadales	S	Predicted integral membrane protein (DUF2282)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2282
k141_786_82	1208321.D104_08895	4.31e-20	82.0	COG5660@1|root,COG5660@2|Bacteria,1NH4R@1224|Proteobacteria,1SH4J@1236|Gammaproteobacteria,1XQTE@135619|Oceanospirillales	135619|Oceanospirillales	S	Putative zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
k141_786_83	717774.Marme_0180	9.11e-83	251.0	COG1595@1|root,COG1595@2|Bacteria,1RHKM@1224|Proteobacteria,1S48U@1236|Gammaproteobacteria,1XK4H@135619|Oceanospirillales	135619|Oceanospirillales	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
k141_786_84	675815.VOA_002739	7.68e-137	391.0	COG4582@1|root,COG4582@2|Bacteria,1MW69@1224|Proteobacteria,1RNPD@1236|Gammaproteobacteria,1XT60@135623|Vibrionales	135623|Vibrionales	D	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity	zapD	GO:0000003,GO:0000910,GO:0005575,GO:0005623,GO:0007049,GO:0008150,GO:0009987,GO:0019954,GO:0022402,GO:0022414,GO:0032153,GO:0032505,GO:0043093,GO:0044464,GO:0051301	-	ko:K18778	-	-	-	-	ko00000,ko03036	-	-	-	ZapD
k141_786_85	675806.VII_001438	3.77e-90	270.0	COG0237@1|root,COG0237@2|Bacteria,1RCXT@1224|Proteobacteria,1S3NR@1236|Gammaproteobacteria,1XW2K@135623|Vibrionales	135623|Vibrionales	F	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A	coaE	GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.1.24	ko:K00859	ko00770,ko01100,map00770,map01100	M00120	R00130	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CoaE
k141_786_86	55601.VANGNB10_cI0470c	5.66e-138	398.0	COG1989@1|root,COG1989@2|Bacteria,1MUZF@1224|Proteobacteria,1RN90@1236|Gammaproteobacteria,1XTYX@135623|Vibrionales	135623|Vibrionales	NOU	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue	pilD	-	3.4.23.43	ko:K02654	-	M00331	-	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	3.A.15.2	-	-	DiS_P_DiS,Peptidase_A24
k141_786_87	945550.VISI1226_02155	1.4e-95	299.0	COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,1RNV0@1236|Gammaproteobacteria,1XV78@135623|Vibrionales	135623|Vibrionales	U	COG1459 Type II secretory pathway, component PulF	pilC	GO:0002790,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008104,GO:0008150,GO:0009297,GO:0009306,GO:0009987,GO:0015031,GO:0015628,GO:0015833,GO:0016020,GO:0016043,GO:0022607,GO:0030030,GO:0030031,GO:0032940,GO:0033036,GO:0042886,GO:0043711,GO:0044085,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0098776	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
k141_786_88	870967.VIS19158_11968	1.34e-141	428.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,1RMBS@1236|Gammaproteobacteria,1XUSD@135623|Vibrionales	135623|Vibrionales	NU	COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB	pilB	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE,T2SSE_N
k141_786_89	1089439.KB902273_gene2262	7.45e-09	59.3	COG4968@1|root,COG4968@2|Bacteria,1N6QE@1224|Proteobacteria,1SCBS@1236|Gammaproteobacteria,46154@72273|Thiotrichales	72273|Thiotrichales	NU	TIGRFAM prepilin-type N-terminal cleavage methylation domain	-	-	-	ko:K02655	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	ComP_DUS,N_methyl
k141_786_92	1348635.BBJY01000018_gene2329	1.18e-75	238.0	COG3464@1|root,COG3464@2|Bacteria,1N2V1@1224|Proteobacteria,1RN1I@1236|Gammaproteobacteria,1XWEU@135623|Vibrionales	135623|Vibrionales	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISL3,HTH_Tnp_ISL3
k141_786_93	55601.VANGNB10_cI0474c	1.37e-166	471.0	COG0157@1|root,COG0157@2|Bacteria,1MW0C@1224|Proteobacteria,1RMBU@1236|Gammaproteobacteria,1XTQ3@135623|Vibrionales	135623|Vibrionales	H	Belongs to the NadC ModD family	nadC	-	2.4.2.19	ko:K00767	ko00760,ko01100,map00760,map01100	M00115	R03348	RC02877	ko00000,ko00001,ko00002,ko01000	-	-	-	QRPTase_C,QRPTase_N
k141_786_94	1219077.VAZ01S_079_00250	1.36e-93	277.0	COG3023@1|root,COG3023@2|Bacteria,1RDHU@1224|Proteobacteria,1S3PG@1236|Gammaproteobacteria,1XTXJ@135623|Vibrionales	135623|Vibrionales	V	COG3023 Negative regulator of beta-lactamase expression	ampD	-	3.5.1.28	ko:K03806	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	Amidase_2
k141_786_96	1219077.VAZ01S_045_00110	4.12e-88	269.0	COG1651@1|root,COG1651@2|Bacteria,1RD39@1224|Proteobacteria,1S3U8@1236|Gammaproteobacteria,1XSD4@135623|Vibrionales	135623|Vibrionales	O	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process	dsbC	-	5.3.4.1	ko:K03981	-	-	-	-	ko00000,ko01000,ko02044,ko03110	3.A.7.11.1	-	-	DsbC_N,Thioredoxin_2
k141_786_97	675806.VII_001448	0.0	929.0	COG0608@1|root,COG0608@2|Bacteria,1MU1M@1224|Proteobacteria,1RMF4@1236|Gammaproteobacteria,1XTR9@135623|Vibrionales	135623|Vibrionales	L	exonuclease recj	recJ	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
k141_786_100	1219065.VPR01S_09_01480	2.23e-313	857.0	COG1249@1|root,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,1RMFF@1236|Gammaproteobacteria,1XT11@135623|Vibrionales	135623|Vibrionales	C	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes	lpdA	GO:0003674,GO:0003824,GO:0004148,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006084,GO:0006085,GO:0006086,GO:0006090,GO:0006139,GO:0006163,GO:0006164,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0032991,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0035383,GO:0035384,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0045250,GO:0045254,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0071616,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902494,GO:1990204	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
k141_786_103	29495.EA26_18245	4.37e-138	392.0	COG0288@1|root,COG0288@2|Bacteria,1NGFN@1224|Proteobacteria,1RSY6@1236|Gammaproteobacteria,1XTY7@135623|Vibrionales	135623|Vibrionales	P	Reversible hydration of carbon dioxide	can	-	4.2.1.1	ko:K01673	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Pro_CA
k141_786_105	345073.VC395_0607	6.16e-148	420.0	COG0842@1|root,COG0842@2|Bacteria,1MUH1@1224|Proteobacteria,1RP0Z@1236|Gammaproteobacteria,1XSC8@135623|Vibrionales	135623|Vibrionales	V	Transport permease protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
k141_786_106	55601.VANGNB10_cI0491c	6.83e-150	428.0	COG0414@1|root,COG0414@2|Bacteria,1MV1S@1224|Proteobacteria,1RMEG@1236|Gammaproteobacteria,1XT8P@135623|Vibrionales	135623|Vibrionales	H	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate	panC	GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605	6.3.2.1	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R02473	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_ligase
k141_786_108	675813.VIB_000307	9.24e-84	250.0	COG0801@1|root,COG0801@2|Bacteria,1MZH8@1224|Proteobacteria,1S63J@1236|Gammaproteobacteria,1XVS1@135623|Vibrionales	135623|Vibrionales	H	COG0801 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase	folK	-	2.7.6.3	ko:K00950	ko00790,ko01100,map00790,map01100	M00126,M00841	R03503	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HPPK
k141_786_109	29495.EA26_18210	8.88e-253	702.0	COG0617@1|root,COG0617@2|Bacteria,1MVCS@1224|Proteobacteria,1RMBG@1236|Gammaproteobacteria,1XT38@135623|Vibrionales	135623|Vibrionales	F	Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control	pcnB	-	2.7.7.19	ko:K00970	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PolyA_pol,PolyA_pol_RNAbd,PolyA_pol_arg_C
k141_786_110	575788.VS_2529	5.39e-147	421.0	COG0008@1|root,COG0008@2|Bacteria,1MUN7@1224|Proteobacteria,1RMYQ@1236|Gammaproteobacteria,1XTZH@135623|Vibrionales	135623|Vibrionales	J	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon	gluQ	-	-	ko:K01894	-	-	-	-	ko00000,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1c
k141_786_112	1191299.AJYX01000064_gene3501	6.66e-116	338.0	COG1489@1|root,COG1489@2|Bacteria,1MUC3@1224|Proteobacteria,1RQ95@1236|Gammaproteobacteria,1XTR1@135623|Vibrionales	135623|Vibrionales	S	Belongs to the SfsA family	sfsA	GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005975,GO:0008150,GO:0008152,GO:0044238,GO:0071704,GO:0097159,GO:1901363	-	ko:K06206	-	-	-	-	ko00000	-	-	-	SfsA
k141_786_113	223926.28807496	0.0	932.0	COG1643@1|root,COG1643@2|Bacteria,1MUEQ@1224|Proteobacteria,1RR1B@1236|Gammaproteobacteria,1XTYU@135623|Vibrionales	135623|Vibrionales	L	ATP-dependent RNA helicase	hrpB	-	3.6.4.13	ko:K03579	-	-	-	-	ko00000,ko01000	-	-	-	DEAD,HA2,Helicase_C,HrpB_C
k141_786_114	675814.VIC_000840	0.0	1120.0	COG0744@1|root,COG0744@2|Bacteria,1QTST@1224|Proteobacteria,1RNHV@1236|Gammaproteobacteria,1XVGW@135623|Vibrionales	135623|Vibrionales	M	Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)	mrcB	GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	2.4.1.129,3.4.16.4	ko:K05365	ko00550,map00550	-	R04519	RC00005,RC00049	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase,UB2H
k141_786_115	55601.VANGNB10_cI0500	1.26e-309	871.0	COG1752@1|root,COG4775@1|root,COG1752@2|Bacteria,COG4775@2|Bacteria,1MUM9@1224|Proteobacteria,1RRSK@1236|Gammaproteobacteria,1XTMT@135623|Vibrionales	135623|Vibrionales	M	esterase of the alpha-beta hydrolase superfamily	VP2496	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	POTRA,Patatin
k141_786_116	55601.VANGNB10_cI0501	0.0	1524.0	COG1049@1|root,COG1049@2|Bacteria,1MVCR@1224|Proteobacteria,1RNMC@1236|Gammaproteobacteria,1XTKU@135623|Vibrionales	135623|Vibrionales	C	Belongs to the aconitase IPM isomerase family	acnB	-	4.2.1.3,4.2.1.99	ko:K01682	ko00020,ko00630,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173	R01324,R01325,R01900,R04425	RC00497,RC00498,RC00618,RC01153	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_2_N,Aconitase_B_N
k141_786_117	870967.VIS19158_04746	1.07e-178	505.0	COG2813@1|root,COG2813@2|Bacteria,1MXE9@1224|Proteobacteria,1RQCH@1236|Gammaproteobacteria,1XUIH@135623|Vibrionales	135623|Vibrionales	J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle	rsmC	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0008990,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0052914,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.172	ko:K00564	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	MTS,MTS_N
k141_786_118	1517681.HW45_00945	8.34e-181	512.0	COG0628@1|root,COG0628@2|Bacteria,1MVX7@1224|Proteobacteria,1RN5Z@1236|Gammaproteobacteria,1XT37@135623|Vibrionales	135623|Vibrionales	S	permease	VP2476	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
k141_786_119	243277.VC_0626	2.34e-272	749.0	COG0001@1|root,COG0001@2|Bacteria,1MUY5@1224|Proteobacteria,1RM7N@1236|Gammaproteobacteria,1XUGV@135623|Vibrionales	135623|Vibrionales	H	Glutamate-1-semialdehyde aminotransferase	hemL	GO:0003674,GO:0003824,GO:0006725,GO:0006778,GO:0006779,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016853,GO:0016866,GO:0016869,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0044237,GO:0044249,GO:0044271,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
k141_1509_1	765910.MARPU_15990	2.79e-82	255.0	COG2113@1|root,COG2113@2|Bacteria,1R5CU@1224|Proteobacteria,1RYZY@1236|Gammaproteobacteria,1WWW3@135613|Chromatiales	135613|Chromatiales	E	glycine betaine	-	-	-	ko:K02002	ko02010,map02010	M00208	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	OpuAC
k141_1509_2	485915.Dret_2272	7.49e-131	379.0	COG4176@1|root,COG4176@2|Bacteria,1MUM4@1224|Proteobacteria,42PAG@68525|delta/epsilon subdivisions,2WM6G@28221|Deltaproteobacteria,2MA4B@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02001	ko02010,map02010	M00208	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	BPD_transp_1
k141_1509_3	1121459.AQXE01000008_gene858	4.38e-160	461.0	COG4175@1|root,COG4175@2|Bacteria,1MU86@1224|Proteobacteria,42MK0@68525|delta/epsilon subdivisions,2WJFN@28221|Deltaproteobacteria,2M8KN@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	TIGRFAM glycine betaine L-proline ABC transporter, ATPase subunit	-	-	3.6.3.32	ko:K02000	ko02010,map02010	M00208	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.12	-	-	ABC_tran,CBS
k141_3908_2	377629.TERTU_1074	1.2e-274	766.0	COG2985@1|root,COG2985@2|Bacteria,1MUVM@1224|Proteobacteria,1RQY2@1236|Gammaproteobacteria,2PP7K@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	P	Predicted Permease Membrane Region	yidE	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K07085	-	-	-	-	ko00000	2.A.81	-	-	Asp-Al_Ex,TrkA_C
k141_3908_3	593105.S7A_07215	2.48e-05	46.6	COG1349@1|root,COG1349@2|Bacteria,1MUJG@1224|Proteobacteria,1RQW3@1236|Gammaproteobacteria,3VXW1@53335|Pantoea	1236|Gammaproteobacteria	K	DeoR C terminal sensor domain	ygbI	GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576	-	ko:K03436	-	-	-	-	ko00000,ko03000	-	-	-	DeoRC,HTH_DeoR
k141_254_1	83406.HDN1F_19090	2.48e-141	424.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,1RMBQ@1236|Gammaproteobacteria,1J88C@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	belongs to the aldehyde dehydrogenase family	-	-	1.2.99.10	ko:K22445	-	-	-	-	ko00000,ko01000	-	-	-	Aldedh
k141_3909_1	243365.CV_0020	2.11e-45	159.0	COG0477@1|root,COG2814@2|Bacteria,1R6GV@1224|Proteobacteria	1224|Proteobacteria	EGP	Major Facilitator	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
k141_3909_2	293826.Amet_2820	4.47e-05	48.1	COG0584@1|root,COG0584@2|Bacteria,1V3W4@1239|Firmicutes,24AVJ@186801|Clostridia,36F9I@31979|Clostridiaceae	186801|Clostridia	C	glycerophosphoryl diester phosphodiesterase	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD,PAP2
k141_4223_1	1056512.D515_03886	8.44e-77	245.0	COG0438@1|root,COG0438@2|Bacteria,1MU9C@1224|Proteobacteria,1RTS0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Glycosyl transferases group 1	lpcC	-	-	ko:K12989	-	-	-	-	ko00000,ko01000,ko01003,ko01005	-	GT4	-	Glyco_transf_4,Glycos_transf_1
k141_4223_2	1238450.VIBNISOn1_480039	2.04e-178	504.0	COG0859@1|root,COG0859@2|Bacteria,1MXA2@1224|Proteobacteria,1RMBF@1236|Gammaproteobacteria,1XTBX@135623|Vibrionales	135623|Vibrionales	M	ADP-heptose--LPS heptosyltransferase II	rfaF	-	-	ko:K02843	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
k141_4223_3	675814.VIC_005056	3.2e-166	473.0	COG0859@1|root,COG0859@2|Bacteria,1NTHI@1224|Proteobacteria,1THBB@1236|Gammaproteobacteria,1XT14@135623|Vibrionales	135623|Vibrionales	M	Lipopolysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_9
k141_4223_4	1051646.VITU9109_12992	1.12e-97	305.0	COG3307@1|root,COG3307@2|Bacteria,1R8PC@1224|Proteobacteria,1RYYV@1236|Gammaproteobacteria,1XWTS@135623|Vibrionales	135623|Vibrionales	M	COG3307 Lipid A core - O-antigen ligase and related enzymes	waaL	-	-	ko:K02847	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01005,ko02000	9.B.67.4,9.B.67.5	-	-	Wzy_C
k141_4223_5	1051646.VITU9109_12982	6.37e-131	377.0	COG3774@1|root,COG3774@2|Bacteria,1PTP7@1224|Proteobacteria,1S33R@1236|Gammaproteobacteria,1XVWC@135623|Vibrionales	135623|Vibrionales	M	COG3774 Mannosyltransferase OCH1 and related enzymes	-	-	-	-	-	-	-	-	-	-	-	-	Gly_transf_sug
k141_4223_6	29495.EA26_01965	2.08e-152	445.0	COG1519@1|root,COG1519@2|Bacteria,1MU9F@1224|Proteobacteria,1RNBR@1236|Gammaproteobacteria,1XTJM@135623|Vibrionales	135623|Vibrionales	M	3-deoxy-D-manno-octulosonic-acid transferase	kdtA	-	2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15	ko:K02527	ko00540,ko01100,map00540,map01100	M00060,M00080	R04658,R05074,R09763	RC00009,RC00077,RC00247	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT30	-	Glycos_transf_1,Glycos_transf_N
k141_4223_7	416269.APL_0979	3.07e-35	139.0	COG0859@1|root,COG0859@2|Bacteria,1R4U8@1224|Proteobacteria,1S8CB@1236|Gammaproteobacteria,1Y6RW@135625|Pasteurellales	135625|Pasteurellales	M	ADP-heptose LPS heptosyltransferase	lbgB	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_9
k141_4223_8	675814.VIC_005053	1.29e-30	118.0	COG3306@1|root,COG3306@2|Bacteria,1R7HN@1224|Proteobacteria,1SAQK@1236|Gammaproteobacteria,1XX32@135623|Vibrionales	135623|Vibrionales	M	Glycosyltransferase family 25 (LPS biosynthesis protein)	-	-	-	ko:K07270	-	-	-	-	ko00000	-	GT25	-	Glyco_transf_25
k141_788_1	674977.VMC_27130	5.49e-142	406.0	COG1524@1|root,COG1524@2|Bacteria,1MYH0@1224|Proteobacteria,1RNQJ@1236|Gammaproteobacteria,1XTNQ@135623|Vibrionales	135623|Vibrionales	S	proteins of the AP superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
k141_788_2	1219065.VPR01S_11_01710	2.21e-99	297.0	COG1840@1|root,COG1840@2|Bacteria,1Q13Q@1224|Proteobacteria,1RWV9@1236|Gammaproteobacteria,1XVMA@135623|Vibrionales	135623|Vibrionales	P	COG1840 ABC-type Fe3 transport system, periplasmic component	-	-	-	ko:K02055	ko02024,map02024	M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11	-	-	SBP_bac_6
k141_4617_2	768671.ThimaDRAFT_4451	6.31e-12	78.2	COG1100@1|root,COG1262@1|root,COG1100@2|Bacteria,COG1262@2|Bacteria,1QH0S@1224|Proteobacteria,1SEPT@1236|Gammaproteobacteria,1X2W3@135613|Chromatiales	135613|Chromatiales	S	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
k141_789_1	933262.AXAM01000003_gene2862	3.48e-58	195.0	COG0795@1|root,COG0795@2|Bacteria,1MUF2@1224|Proteobacteria,42NYD@68525|delta/epsilon subdivisions,2WKHT@28221|Deltaproteobacteria,2MHU9@213118|Desulfobacterales	28221|Deltaproteobacteria	S	permease YjgP YjgQ family	lptF	-	-	ko:K07091	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
k141_3568_1	796620.VIBC2010_10097	3.89e-54	204.0	COG3008@1|root,COG3008@2|Bacteria,1MU1T@1224|Proteobacteria,1RN89@1236|Gammaproteobacteria,1XTE9@135623|Vibrionales	135623|Vibrionales	Q	Paraquat-inducible protein B	-	-	-	-	-	-	-	-	-	-	-	-	MlaD
k141_4224_1	1121413.JMKT01000002_gene2658	3.52e-80	254.0	COG2710@1|root,COG2710@2|Bacteria,1MVY2@1224|Proteobacteria,42MMI@68525|delta/epsilon subdivisions,2WJZI@28221|Deltaproteobacteria,2M8BC@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	TIGRFAM Nitrogenase molybdenum-iron protein alpha chain	nifD	-	1.18.6.1	ko:K02586	ko00625,ko00910,ko01100,ko01120,map00625,map00910,map01100,map01120	M00175	R05185,R05496	RC00002,RC01395,RC02891	ko00000,ko00001,ko00002,ko01000	-	-	-	Oxidored_nitro
k141_4224_2	555779.Dthio_PD2918	6.06e-44	147.0	COG0347@1|root,COG0347@2|Bacteria,1RKW3@1224|Proteobacteria,42SE6@68525|delta/epsilon subdivisions,2WP2V@28221|Deltaproteobacteria,2MBX0@213115|Desulfovibrionales	28221|Deltaproteobacteria	K	Belongs to the P(II) protein family	-	-	-	ko:K02590	-	-	-	-	ko00000	-	-	-	P-II
k141_4224_3	1121413.JMKT01000002_gene2660	4.36e-52	166.0	COG0347@1|root,COG0347@2|Bacteria,1RIX2@1224|Proteobacteria,42SFQ@68525|delta/epsilon subdivisions,2WPG3@28221|Deltaproteobacteria,2MBYT@213115|Desulfovibrionales	28221|Deltaproteobacteria	K	Belongs to the P(II) protein family	-	-	-	ko:K02589	-	-	-	-	ko00000	-	-	-	P-II
k141_4224_4	525897.Dbac_0834	5.3e-151	428.0	COG1348@1|root,COG1348@2|Bacteria,1MVTE@1224|Proteobacteria,42NE5@68525|delta/epsilon subdivisions,2WJ14@28221|Deltaproteobacteria,2M97I@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components the iron protein and the molybdenum-iron protein	nifH	-	1.18.6.1	ko:K02588	ko00625,ko00910,ko01100,ko01120,map00625,map00910,map01100,map01120	M00175	R05185,R05496	RC00002,RC01395,RC02891	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4_NifH
k141_255_2	933262.AXAM01000003_gene2805	2.22e-50	170.0	COG0727@1|root,COG0727@2|Bacteria,1RIJV@1224|Proteobacteria,42U8U@68525|delta/epsilon subdivisions,2WPB4@28221|Deltaproteobacteria,2MKIE@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Putative zinc- or iron-chelating domain	-	-	-	-	-	-	-	-	-	-	-	-	CxxCxxCC
k141_255_3	1304885.AUEY01000014_gene3335	0.0	962.0	COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1145@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1145@2|Bacteria,1MVM0@1224|Proteobacteria,42MZ0@68525|delta/epsilon subdivisions,2WJ96@28221|Deltaproteobacteria,2MHRJ@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	poR	-	1.2.7.1	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00173,M00307	R01196,R10866	RC00004,RC02742	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	EKR,Fer4_16,PFOR_II,POR,POR_N,TPP_enzyme_C
k141_4619_1	1304885.AUEY01000058_gene2321	2.18e-167	483.0	COG0064@1|root,COG0064@2|Bacteria,1MUKG@1224|Proteobacteria,42M31@68525|delta/epsilon subdivisions,2WJK4@28221|Deltaproteobacteria,2MIIZ@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
k141_790_1	177437.HRM2_05700	1.31e-164	487.0	COG0826@1|root,COG0826@2|Bacteria,1MUQG@1224|Proteobacteria,42MCC@68525|delta/epsilon subdivisions,2WKJK@28221|Deltaproteobacteria,2MJAE@213118|Desulfobacterales	28221|Deltaproteobacteria	O	peptidase U32	-	-	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	DUF3656,Peptidase_U32
k141_1511_1	1304885.AUEY01000030_gene2414	0.0	1044.0	COG2203@1|root,COG2804@1|root,COG2203@2|Bacteria,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,42P9Y@68525|delta/epsilon subdivisions,2WM6A@28221|Deltaproteobacteria,2MJCC@213118|Desulfobacterales	28221|Deltaproteobacteria	NTU	General secretory system II protein E domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,T2SSE,T2SSE_N
k141_4620_1	1397699.JNIS01000001_gene1771	8.77e-07	56.2	COG0840@1|root,COG0840@2|Bacteria,1TP5A@1239|Firmicutes,4H9RZ@91061|Bacilli,3WF7S@539002|Bacillales incertae sedis	91061|Bacilli	NT	histidine kinase HAMP region domain protein	cheW5	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal,dCache_1
k141_256_2	485915.Dret_1799	3.08e-10	61.6	COG1971@1|root,COG1971@2|Bacteria,1NWBY@1224|Proteobacteria,42RE2@68525|delta/epsilon subdivisions,2WNEN@28221|Deltaproteobacteria,2MB2K@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	Probably functions as a manganese efflux pump	mntP	-	-	-	-	-	-	-	-	-	-	-	Mntp
k141_5098_1	1121396.KB893100_gene4331	1.12e-235	667.0	COG0840@1|root,COG3287@1|root,COG0840@2|Bacteria,COG3287@2|Bacteria,1MVUZ@1224|Proteobacteria,42MYH@68525|delta/epsilon subdivisions,2X5DY@28221|Deltaproteobacteria,2MMP0@213118|Desulfobacterales	28221|Deltaproteobacteria	NT	FIST N domain	-	-	-	-	-	-	-	-	-	-	-	-	FIST,FIST_C,MCPsignal
k141_5098_2	1121459.AQXE01000001_gene2573	7.76e-08	58.2	2AHV7@1|root,31880@2|Bacteria,1P05S@1224|Proteobacteria,431BZ@68525|delta/epsilon subdivisions,2WWE3@28221|Deltaproteobacteria,2MDCU@213115|Desulfovibrionales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_4340_1	55601.VANGNB10_cII0451c	6.25e-53	174.0	COG0583@1|root,COG0583@2|Bacteria,1MZTA@1224|Proteobacteria,1RN7R@1236|Gammaproteobacteria,1XSKB@135623|Vibrionales	135623|Vibrionales	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
k141_4340_2	1219065.VPR01S_07_01070	9.06e-76	232.0	COG3266@1|root,COG3266@2|Bacteria,1QJDK@1224|Proteobacteria,1THCR@1236|Gammaproteobacteria,1XU08@135623|Vibrionales	135623|Vibrionales	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	SPOR
k141_4340_3	945543.VIBR0546_04097	3.58e-124	362.0	COG1181@1|root,COG1181@2|Bacteria,1MUTB@1224|Proteobacteria,1RMTM@1236|Gammaproteobacteria,1XUIJ@135623|Vibrionales	135623|Vibrionales	F	Belongs to the D-alanine--D-alanine ligase family	ddl	GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008716,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
k141_5099_2	177437.HRM2_12370	1.24e-58	203.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,42NAV@68525|delta/epsilon subdivisions,2WJ3W@28221|Deltaproteobacteria,2MIIB@213118|Desulfobacterales	28221|Deltaproteobacteria	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
k141_5101_1	1167006.UWK_01797	4.15e-28	112.0	COG0673@1|root,COG1063@1|root,COG0673@2|Bacteria,COG1063@2|Bacteria,1PDZZ@1224|Proteobacteria,42M63@68525|delta/epsilon subdivisions,2WJDW@28221|Deltaproteobacteria,2MJCU@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	ADH_zinc_N,GFO_IDH_MocA
k141_667_2	1348635.BBJY01000009_gene1635	1.29e-98	294.0	COG1136@1|root,COG1136@2|Bacteria,1RA1K@1224|Proteobacteria,1S275@1236|Gammaproteobacteria,1XUZ7@135623|Vibrionales	135623|Vibrionales	V	COG1136 ABC-type antimicrobial peptide transport system, ATPase component	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
k141_667_3	1187848.AJYQ01000109_gene513	4.26e-225	629.0	COG0577@1|root,COG0577@2|Bacteria,1MVN1@1224|Proteobacteria,1RNVN@1236|Gammaproteobacteria,1XU5T@135623|Vibrionales	135623|Vibrionales	V	ABC-type antimicrobial peptide transport system, permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
k141_667_4	1136163.M565_ctg4P057	4.66e-65	203.0	COG3495@1|root,COG3495@2|Bacteria,1RB8H@1224|Proteobacteria,1S8DT@1236|Gammaproteobacteria,1XX0Z@135623|Vibrionales	135623|Vibrionales	S	protein conserved in bacteria	-	-	-	ko:K09950	-	-	-	-	ko00000	-	-	-	DUF3299
k141_667_5	1348635.BBJY01000009_gene1632	3.22e-128	374.0	2AX1N@1|root,31NZV@2|Bacteria,1RI5Q@1224|Proteobacteria,1S6GI@1236|Gammaproteobacteria,1XTQU@135623|Vibrionales	135623|Vibrionales	S	Protein of unknown function (DUF2806)	VV10722	-	-	-	-	-	-	-	-	-	-	-	DUF2806
k141_667_6	55601.VANGNB10_cI2309c	4.03e-119	343.0	COG0529@1|root,COG0529@2|Bacteria,1MX0D@1224|Proteobacteria,1RNWT@1236|Gammaproteobacteria,1XUJT@135623|Vibrionales	135623|Vibrionales	F	Catalyzes the synthesis of activated sulfate	cysC	GO:0003674,GO:0003824,GO:0004020,GO:0006790,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237	2.7.1.25	ko:K00860	ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120	M00176	R00509,R04928	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase
k141_667_7	674977.VMC_03690	3e-278	771.0	COG2895@1|root,COG2895@2|Bacteria,1MUD9@1224|Proteobacteria,1RME4@1236|Gammaproteobacteria,1XSCY@135623|Vibrionales	135623|Vibrionales	H	Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily	cysN	GO:0003674,GO:0003824,GO:0004779,GO:0004781,GO:0006790,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0044237,GO:0070566	2.7.7.4	ko:K00956	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R04929	RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_EFTU
k141_668_1	545697.HMPREF0216_02394	1.63e-20	90.1	COG3859@1|root,COG3859@2|Bacteria,1V1WX@1239|Firmicutes,24E4Z@186801|Clostridia,36IVJ@31979|Clostridiaceae	186801|Clostridia	S	Proton-coupled thiamine transporter YuaJ	yuaJ	-	-	ko:K16789	-	-	-	-	ko00000,ko02000	2.A.88.3	-	-	Thia_YuaJ
k141_4341_1	491205.JARQ01000002_gene266	2.25e-06	48.5	COG1359@1|root,COG1359@2|Bacteria,4NXQZ@976|Bacteroidetes,1I5SG@117743|Flavobacteriia,3ZS8K@59732|Chryseobacterium	976|Bacteroidetes	S	Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	ABM
k141_4341_2	1208321.D104_18190	3.3e-124	365.0	COG0697@1|root,COG0697@2|Bacteria,1PGSE@1224|Proteobacteria,1RMZY@1236|Gammaproteobacteria,1XPQY@135619|Oceanospirillales	135619|Oceanospirillales	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
k141_669_2	1348635.BBJY01000003_gene3857	1.35e-43	151.0	COG4977@1|root,COG4977@2|Bacteria,1MUDK@1224|Proteobacteria,1RQAG@1236|Gammaproteobacteria,1Y2JU@135623|Vibrionales	135623|Vibrionales	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
k141_669_3	1028307.EAE_21600	6.54e-72	228.0	COG4992@1|root,COG4992@2|Bacteria,1MV3C@1224|Proteobacteria,1RMV1@1236|Gammaproteobacteria,3X1NX@547|Enterobacter	1236|Gammaproteobacteria	E	Involved in both the arginine and lysine biosynthetic pathways	argD	GO:0003674,GO:0003824,GO:0003992,GO:0004069,GO:0005488,GO:0005515,GO:0006082,GO:0006105,GO:0006520,GO:0006525,GO:0006526,GO:0006527,GO:0006591,GO:0006593,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009064,GO:0009065,GO:0009084,GO:0009987,GO:0016053,GO:0016054,GO:0016740,GO:0016769,GO:0017144,GO:0019545,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0042450,GO:0042802,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043825,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0046394,GO:0046395,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607	2.6.1.11,2.6.1.17,2.6.1.81	ko:K00821,ko:K00840	ko00220,ko00300,ko00330,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map00330,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04217,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	iAPECO1_1312.APECO1_817,iEC55989_1330.EC55989_1916,iECABU_c1320.ECABU_c20050,iECED1_1282.ECED1_1950,iECOK1_1307.ECOK1_1868,iECP_1309.ECP_1694,iECS88_1305.ECS88_1800,iEcSMS35_1347.EcSMS35_1443,iUMN146_1321.UM146_08405,iUTI89_1310.UTI89_C1943,ic_1306.c2148	Aminotran_3
k141_4346_1	177437.HRM2_33480	3.18e-43	152.0	COG1651@1|root,COG1651@2|Bacteria,1Q9JZ@1224|Proteobacteria,42R87@68525|delta/epsilon subdivisions,2WN18@28221|Deltaproteobacteria,2MJGH@213118|Desulfobacterales	28221|Deltaproteobacteria	O	Thioredoxin-like domain	-	-	5.3.4.1	ko:K03981	-	-	-	-	ko00000,ko01000,ko02044,ko03110	3.A.7.11.1	-	-	Thioredoxin_2
k141_4065_2	675813.VIB_001221	4.2e-76	244.0	COG0443@1|root,COG0443@2|Bacteria,1MXX7@1224|Proteobacteria,1RQ12@1236|Gammaproteobacteria,1XTFW@135623|Vibrionales	135623|Vibrionales	O	Belongs to the heat shock protein 70 family	-	-	-	-	-	-	-	-	-	-	-	-	HSP70
k141_4371_1	439235.Dalk_2733	3.27e-21	95.9	COG2215@1|root,COG2215@2|Bacteria,1MWIW@1224|Proteobacteria,42V1K@68525|delta/epsilon subdivisions,2WRAG@28221|Deltaproteobacteria,2MKWK@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Belongs to the NiCoT transporter (TC 2.A.52) family	-	-	-	-	-	-	-	-	-	-	-	-	NicO
k141_4371_2	864702.OsccyDRAFT_4073	3.01e-10	60.5	COG1611@1|root,COG1611@2|Bacteria,1G5P3@1117|Cyanobacteria,1HB1W@1150|Oscillatoriales	1117|Cyanobacteria	S	Rossmann fold nucleotide-binding protein	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
k141_4066_1	1515746.HR45_12970	8.72e-191	559.0	COG1289@1|root,COG1289@2|Bacteria,1MX9H@1224|Proteobacteria,1RMJ4@1236|Gammaproteobacteria,2QD4G@267890|Shewanellaceae	1236|Gammaproteobacteria	S	Fusaric acid resistance protein family	-	-	-	-	-	-	-	-	-	-	-	-	FUSC
k141_4067_1	1304885.AUEY01000064_gene2128	8.26e-30	113.0	COG0714@1|root,COG0714@2|Bacteria,1MV5I@1224|Proteobacteria,42N5A@68525|delta/epsilon subdivisions,2WKKI@28221|Deltaproteobacteria,2MIZW@213118|Desulfobacterales	28221|Deltaproteobacteria	S	AAA ATPase domain	clpB1	-	-	-	-	-	-	-	-	-	-	-	AAA,AAA_5
k141_2657_2	1238450.VIBNISOn1_p0043	2.67e-05	45.8	COG0524@1|root,COG0524@2|Bacteria,1MV5B@1224|Proteobacteria,1RNVY@1236|Gammaproteobacteria,1XUEM@135623|Vibrionales	135623|Vibrionales	H	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway	rbsK	-	2.7.1.15	ko:K00852	ko00030,map00030	-	R01051,R02750	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
k141_2657_4	675814.VIC_003291	1.77e-08	58.2	COG0834@1|root,COG0834@2|Bacteria,1RJRT@1224|Proteobacteria,1S7XT@1236|Gammaproteobacteria,1XT9A@135623|Vibrionales	135623|Vibrionales	ET	ABC-type amino acid transport signal transduction systems, periplasmic component	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
k141_2657_6	595494.Tola_1653	9.4e-47	160.0	COG0673@1|root,COG0673@2|Bacteria,1MZIG@1224|Proteobacteria,1RS5T@1236|Gammaproteobacteria,1Y4UQ@135624|Aeromonadales	135624|Aeromonadales	S	Oxidoreductase	-	-	-	ko:K22230	ko00562,ko01120,map00562,map01120	-	R09954	RC00182	ko00000,ko00001,ko01000	-	-	-	GFO_IDH_MocA
k141_2657_7	198628.Dda3937_04120	2.11e-64	209.0	COG0673@1|root,COG0673@2|Bacteria,1MZIG@1224|Proteobacteria,1RS5T@1236|Gammaproteobacteria,2JETW@204037|Dickeya	1236|Gammaproteobacteria	C	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
k141_4069_1	879212.DespoDRAFT_02978	5e-71	237.0	COG3605@1|root,COG3605@2|Bacteria,1QTTV@1224|Proteobacteria,42PST@68525|delta/epsilon subdivisions,2WJ3A@28221|Deltaproteobacteria,2MIS5@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Belongs to the PEP-utilizing enzyme family	ptsP	-	2.7.3.9	ko:K08484	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	-	-	-	GAF_2,PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C
k141_5326_1	55601.VANGNB10_cII0103	2.59e-218	629.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,1XVCZ@135623|Vibrionales	135623|Vibrionales	NT	methyl-accepting chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal,dCache_1
k141_5326_2	243277.VC_A0025	3.32e-253	704.0	COG0471@1|root,COG0471@2|Bacteria,1MUSA@1224|Proteobacteria,1RPU5@1236|Gammaproteobacteria,1XVCC@135623|Vibrionales	135623|Vibrionales	P	COG0471 Di- and tricarboxylate transporters	-	-	-	ko:K14445	-	-	-	-	ko00000,ko02000	2.A.47.1	-	-	Na_sulph_symp
k141_5326_3	1280001.BAOA01000027_gene4879	2.41e-107	322.0	COG0679@1|root,COG0679@2|Bacteria,1N1X9@1224|Proteobacteria,1RMV0@1236|Gammaproteobacteria,1XSDV@135623|Vibrionales	135623|Vibrionales	S	Membrane transport protein	-	-	-	ko:K07088	-	-	-	-	ko00000	-	-	-	Mem_trans
k141_5326_4	595494.Tola_0997	6.58e-35	125.0	COG1309@1|root,COG1309@2|Bacteria,1RA4T@1224|Proteobacteria,1RNQH@1236|Gammaproteobacteria,1Y699@135624|Aeromonadales	135624|Aeromonadales	K	Bacterial transcriptional repressor C-terminal	-	-	-	ko:K16137	-	-	-	-	ko00000,ko03000	-	-	-	TetR_C_13,TetR_N
k141_2658_2	595494.Tola_1659	6.62e-35	125.0	COG2050@1|root,COG2050@2|Bacteria,1N1FK@1224|Proteobacteria,1SBSR@1236|Gammaproteobacteria,1Y5ZP@135624|Aeromonadales	135624|Aeromonadales	Q	PFAM thioesterase superfamily protein	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
k141_2658_3	637910.ROD_45281	4.72e-31	114.0	2D7FD@1|root,32TNY@2|Bacteria,1NAHU@1224|Proteobacteria,1S9DD@1236|Gammaproteobacteria,3WYFJ@544|Citrobacter	1236|Gammaproteobacteria	S	Domain of unknown function (DUF1992)	yhdN	-	-	-	-	-	-	-	-	-	-	-	DUF1992
k141_2658_4	339671.Asuc_2009	9.95e-84	256.0	COG1811@1|root,COG1811@2|Bacteria,1MX1D@1224|Proteobacteria,1RYSH@1236|Gammaproteobacteria,1Y86G@135625|Pasteurellales	135625|Pasteurellales	S	Protein of unknown function (DUF554)	-	-	-	ko:K07150	-	-	-	-	ko00000	-	-	-	DUF554
k141_4070_1	345073.VC395_A0551	3.6e-199	572.0	COG0714@1|root,COG0714@2|Bacteria,1PC08@1224|Proteobacteria,1RQ5U@1236|Gammaproteobacteria,1XSDT@135623|Vibrionales	135623|Vibrionales	S	COG0714 MoxR-like ATPases	ravA	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_5,DUF3763
k141_4376_1	1123508.JH636439_gene1391	5.97e-90	302.0	COG4191@1|root,COG4191@2|Bacteria,2IWUM@203682|Planctomycetes	203682|Planctomycetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
k141_4376_2	589865.DaAHT2_2622	1.13e-187	539.0	COG0702@1|root,COG0702@2|Bacteria,1PDTN@1224|Proteobacteria,42M8X@68525|delta/epsilon subdivisions,2WJ5J@28221|Deltaproteobacteria,2MHQP@213118|Desulfobacterales	28221|Deltaproteobacteria	GM	Protein of unknown function (DUF2867)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2867,NAD_binding_10
k141_2659_1	522772.Dacet_0974	8.45e-48	162.0	COG4239@1|root,COG4239@2|Bacteria	2|Bacteria	P	microcin transport	yejE	GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006857,GO:0008150,GO:0015833,GO:0015893,GO:0016020,GO:0035672,GO:0042221,GO:0042493,GO:0042884,GO:0042886,GO:0042891,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944	-	ko:K02034,ko:K13895	ko02010,ko02024,map02010,map02024	M00239,M00349	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.21,3.A.1.5.24	-	-	BPD_transp_1,OppC_N
k141_959_7	1511.CLOST_1587	3.29e-108	314.0	COG0231@1|root,COG0231@2|Bacteria,1TR8P@1239|Firmicutes,249DV@186801|Clostridia,25QK1@186804|Peptostreptococcaceae	186801|Clostridia	J	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase	efp	-	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
k141_959_8	1476973.JMMB01000007_gene1007	2.8e-14	71.6	2E3FE@1|root,32YE8@2|Bacteria,1VFR0@1239|Firmicutes,24SIH@186801|Clostridia,25RW2@186804|Peptostreptococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_959_9	1286171.EAL2_c14300	2.84e-134	391.0	COG1702@1|root,COG1702@2|Bacteria,1TP35@1239|Firmicutes,247ZJ@186801|Clostridia,25V1W@186806|Eubacteriaceae	186801|Clostridia	T	phosphate starvation-inducible protein	phoH	-	-	ko:K06217	-	-	-	-	ko00000	-	-	-	PhoH
k141_959_10	1476973.JMMB01000007_gene2658	1.89e-62	196.0	COG0319@1|root,COG0319@2|Bacteria,1V6BU@1239|Firmicutes,24MQZ@186801|Clostridia,25RAP@186804|Peptostreptococcaceae	186801|Clostridia	S	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA	ybeY	-	3.5.4.5	ko:K01489,ko:K07042	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01878,R02485,R08221	RC00074,RC00514	ko00000,ko00001,ko01000,ko03009	-	-	-	UPF0054
k141_959_11	1511.CLOST_1776	9.81e-50	169.0	COG0671@1|root,COG0818@1|root,COG0671@2|Bacteria,COG0818@2|Bacteria,1VEGR@1239|Firmicutes,248FD@186801|Clostridia,25QEG@186804|Peptostreptococcaceae	186801|Clostridia	IM	Prokaryotic diacylglycerol kinase	dgkA	-	2.7.1.107,2.7.1.66	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	-	R02240,R05626	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	DAGK_prokar,PAP2
k141_959_12	926561.KB900617_gene1765	3.66e-50	168.0	COG2928@1|root,COG2928@2|Bacteria,1V6FM@1239|Firmicutes,24JQ1@186801|Clostridia,3WBT4@53433|Halanaerobiales	186801|Clostridia	S	Protein of unknown function (DUF502)	-	-	-	-	-	-	-	-	-	-	-	-	DUF502
k141_959_13	857293.CAAU_0509	3.23e-62	193.0	COG0295@1|root,COG0295@2|Bacteria,1V6IP@1239|Firmicutes,24JEM@186801|Clostridia,36JJ5@31979|Clostridiaceae	186801|Clostridia	F	This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis	cdd	-	3.5.4.5	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01878,R02485,R08221	RC00074,RC00514	ko00000,ko00001,ko01000	-	-	-	dCMP_cyt_deam_1
k141_959_14	1219626.HMPREF1639_00725	1.69e-148	425.0	COG1159@1|root,COG1159@2|Bacteria,1TP3R@1239|Firmicutes,24876@186801|Clostridia,25QEP@186804|Peptostreptococcaceae	186801|Clostridia	S	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism	era	-	-	ko:K03595	-	-	-	-	ko00000,ko03009,ko03029	-	-	-	KH_2,MMR_HSR1
k141_959_15	1286171.EAL2_c14250	8.64e-168	487.0	COG2239@1|root,COG2239@2|Bacteria,1TP4V@1239|Firmicutes,2481R@186801|Clostridia,25VPU@186806|Eubacteriaceae	186801|Clostridia	P	Acts as a magnesium transporter	mgtE	-	-	ko:K06213	-	-	-	-	ko00000,ko02000	1.A.26.1	-	-	CBS,MgtE,MgtE_N
k141_959_16	1476973.JMMB01000007_gene2653	3.96e-62	202.0	COG1381@1|root,COG1381@2|Bacteria,1UZ19@1239|Firmicutes,249TI@186801|Clostridia,25R8U@186804|Peptostreptococcaceae	186801|Clostridia	L	Involved in DNA repair and RecF pathway recombination	recO	-	-	ko:K03584	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecO_C,RecO_N
k141_959_17	1121324.CLIT_11c01200	4.23e-51	169.0	COG1308@1|root,COG1308@2|Bacteria,1V7I9@1239|Firmicutes,24M6Q@186801|Clostridia,25RXG@186804|Peptostreptococcaceae	186801|Clostridia	K	Domain of unknown function (DUF4342)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4342
k141_959_18	1476973.JMMB01000007_gene2651	3.26e-179	502.0	COG0752@1|root,COG0752@2|Bacteria,1TPW8@1239|Firmicutes,24AU0@186801|Clostridia,25R89@186804|Peptostreptococcaceae	186801|Clostridia	J	Glycyl-tRNA synthetase alpha	glyQ	-	6.1.1.14	ko:K01878	ko00970,map00970	M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2e
k141_959_19	1151292.QEW_2986	1.81e-291	819.0	COG0751@1|root,COG0751@2|Bacteria,1TNZ7@1239|Firmicutes,248RS@186801|Clostridia,25R5C@186804|Peptostreptococcaceae	186801|Clostridia	J	Glycyl-tRNA synthetase beta subunit	glyS	-	6.1.1.14	ko:K01879	ko00970,map00970	M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_1,tRNA_synt_2f
k141_959_20	1121324.CLIT_11c01210	4.27e-94	280.0	COG0517@1|root,COG0517@2|Bacteria,1TRZD@1239|Firmicutes,24851@186801|Clostridia,25UNT@186804|Peptostreptococcaceae	186801|Clostridia	K	Domain in cystathionine beta-synthase and other proteins.	ccpN	-	-	-	-	-	-	-	-	-	-	-	CBS,HTH_11
k141_959_21	1121324.CLIT_11c01220	3.18e-134	387.0	COG1806@1|root,COG1806@2|Bacteria,1TPG0@1239|Firmicutes,249ID@186801|Clostridia	186801|Clostridia	S	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation	yqfL	-	2.7.11.33,2.7.4.28	ko:K09773	-	-	-	-	ko00000,ko01000	-	-	-	Kinase-PPPase
k141_959_22	1286171.EAL2_c21040	0.0	1229.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia,25VEG@186806|Eubacteriaceae	186801|Clostridia	G	Belongs to the PEP-utilizing enzyme family	ppdK	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
k141_959_23	941824.TCEL_02082	6.83e-159	459.0	COG0025@1|root,COG0025@2|Bacteria,1UHUI@1239|Firmicutes,25E2Y@186801|Clostridia,36UH5@31979|Clostridiaceae	186801|Clostridia	P	Sodium/hydrogen exchanger family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
k141_959_24	293826.Amet_4648	1.06e-244	698.0	COG0021@1|root,COG0021@2|Bacteria,1TPIB@1239|Firmicutes,25E6C@186801|Clostridia,36UJ4@31979|Clostridiaceae	186801|Clostridia	G	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate	tkt	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
k141_959_25	1391646.AVSU01000009_gene39	4.14e-227	638.0	COG1362@1|root,COG1362@2|Bacteria,1TP6G@1239|Firmicutes,2486Y@186801|Clostridia,25QU6@186804|Peptostreptococcaceae	186801|Clostridia	E	M18 family aminopeptidase	apeA	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M18
k141_959_26	1280671.AUJH01000003_gene1396	4.48e-05	46.6	2DQHF@1|root,336V9@2|Bacteria,1VIX0@1239|Firmicutes,24T9J@186801|Clostridia,4BZ4U@830|Butyrivibrio	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_959_28	1408422.JHYF01000017_gene1894	9.42e-112	328.0	COG0171@1|root,COG0171@2|Bacteria,1TQ38@1239|Firmicutes,2484Z@186801|Clostridia	186801|Clostridia	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses	nadE	-	6.3.1.5	ko:K01916	ko00760,ko01100,map00760,map01100	M00115	R00189	RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	NAD_synthase
k141_959_29	1121289.JHVL01000041_gene3068	2.71e-109	327.0	COG0003@1|root,COG0003@2|Bacteria,1TQZP@1239|Firmicutes,249JN@186801|Clostridia,36FM0@31979|Clostridiaceae	186801|Clostridia	D	Arsenite-activated ATPase ArsA	-	-	3.6.3.16	ko:K01551	-	-	-	-	ko00000,ko01000,ko02000	3.A.19.1,3.A.21.1,3.A.4.1	-	-	ArsA_ATPase
k141_959_30	891968.Anamo_0332	7.59e-14	68.2	arCOG03655@1|root,32S08@2|Bacteria,3TBHS@508458|Synergistetes	508458|Synergistetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_959_33	1410653.JHVC01000005_gene2503	1.52e-72	267.0	COG3629@1|root,COG3899@1|root,COG3629@2|Bacteria,COG3899@2|Bacteria,1TR6V@1239|Firmicutes,24AA2@186801|Clostridia,36DWM@31979|Clostridiaceae	186801|Clostridia	T	Bacterial transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,BTAD,TPR_12,Trans_reg_C
k141_959_34	500633.CLOHIR_01123	5.29e-243	696.0	COG1200@1|root,COG1200@2|Bacteria,1TQ6I@1239|Firmicutes,247T0@186801|Clostridia,25QY1@186804|Peptostreptococcaceae	186801|Clostridia	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
k141_959_35	1391646.AVSU01000054_gene1179	3.38e-62	197.0	COG0742@1|root,COG0742@2|Bacteria,1V3JF@1239|Firmicutes,24JHR@186801|Clostridia,25RB7@186804|Peptostreptococcaceae	186801|Clostridia	L	RNA methyltransferase, RsmD family	rsmD	-	2.1.1.171	ko:K08316	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Cons_hypoth95
k141_959_36	755731.Clo1100_2221	9.09e-61	192.0	COG0669@1|root,COG0669@2|Bacteria,1V3MR@1239|Firmicutes,24HC3@186801|Clostridia,36IRH@31979|Clostridiaceae	186801|Clostridia	H	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	-	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
k141_959_37	273068.TTE1485	1.15e-11	66.2	COG1193@1|root,COG1193@2|Bacteria,1UHZ5@1239|Firmicutes,25E7T@186801|Clostridia,42GTB@68295|Thermoanaerobacterales	186801|Clostridia	L	negative regulation of DNA recombination	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_959_38	272563.CD630_11740	2.65e-125	376.0	COG1323@1|root,COG1323@2|Bacteria,1TPP2@1239|Firmicutes,247UP@186801|Clostridia,25QMM@186804|Peptostreptococcaceae	186801|Clostridia	S	Belongs to the UPF0348 family	-	-	-	-	-	-	-	-	-	-	-	-	HIGH_NTase1
k141_959_39	1286171.EAL2_c13070	4.62e-105	312.0	COG1968@1|root,COG1968@2|Bacteria,1TPFA@1239|Firmicutes,249KK@186801|Clostridia,25VRX@186806|Eubacteriaceae	186801|Clostridia	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
k141_959_40	293826.Amet_2618	2.77e-203	572.0	COG0436@1|root,COG0436@2|Bacteria,1TP0J@1239|Firmicutes,247NQ@186801|Clostridia,36DT7@31979|Clostridiaceae	186801|Clostridia	E	Aminotransferase	-	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	iHN637.CLJU_RS10450	Aminotran_1_2
k141_959_41	1286171.EAL2_c13040	1.18e-46	154.0	2EB46@1|root,3354W@2|Bacteria,1VGP3@1239|Firmicutes,24J4K@186801|Clostridia	186801|Clostridia	S	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
k141_5329_1	1123487.KB892857_gene2474	3.15e-10	68.2	COG0705@1|root,COG0705@2|Bacteria,1MYFP@1224|Proteobacteria,2VPBJ@28216|Betaproteobacteria	28216|Betaproteobacteria	S	PFAM Rhomboid family protein	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
k141_1054_15	1209989.TepiRe1_2570	4.32e-21	86.7	COG2002@1|root,COG2002@2|Bacteria,1V8G8@1239|Firmicutes,24JVE@186801|Clostridia,42IPR@68295|Thermoanaerobacterales	186801|Clostridia	K	SpoVT / AbrB like domain	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_1054_16	457396.CSBG_01431	2.85e-16	84.7	COG0551@1|root,COG0551@2|Bacteria,1V93W@1239|Firmicutes,24CEN@186801|Clostridia,36IXA@31979|Clostridiaceae	186801|Clostridia	L	NERD domain protein	-	-	-	-	-	-	-	-	-	-	-	-	NERD,zf-C4_Topoisom
k141_1054_18	1121289.JHVL01000007_gene2727	4.81e-72	217.0	COG3620@1|root,COG3620@2|Bacteria,1VE10@1239|Firmicutes,24MPW@186801|Clostridia	186801|Clostridia	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
k141_1054_19	1121289.JHVL01000007_gene2728	8.04e-199	552.0	COG2856@1|root,COG2856@2|Bacteria,1V013@1239|Firmicutes,24CWK@186801|Clostridia,36Q22@31979|Clostridiaceae	186801|Clostridia	E	IrrE N-terminal-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M78
k141_1054_20	1121289.JHVL01000007_gene2729	1.65e-149	422.0	29P90@1|root,30A74@2|Bacteria,1V5NA@1239|Firmicutes,24WQ2@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_1054_22	469596.HMPREF9488_00419	1.99e-15	76.6	COG5652@1|root,COG5652@2|Bacteria,1VF6Q@1239|Firmicutes,3VRNT@526524|Erysipelotrichia	526524|Erysipelotrichia	S	VanZ like family	-	-	-	-	-	-	-	-	-	-	-	-	VanZ
k141_1054_23	1294265.JCM21738_3880	6e-228	634.0	COG1004@1|root,COG1004@2|Bacteria,1TQFN@1239|Firmicutes,4HADP@91061|Bacilli,1ZAP3@1386|Bacillus	91061|Bacilli	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	ugd	GO:0003674,GO:0003824,GO:0003979,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016616,GO:0055114	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
k141_1054_24	768706.Desor_5128	3.3e-204	571.0	COG1088@1|root,COG1088@2|Bacteria,1TPWM@1239|Firmicutes,247NE@186801|Clostridia,26192@186807|Peptococcaceae	186801|Clostridia	M	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily	rfbB	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
k141_1054_25	994573.T472_0204595	9.08e-259	718.0	COG1091@1|root,COG1898@1|root,COG1091@2|Bacteria,COG1898@2|Bacteria,1TP71@1239|Firmicutes,247PG@186801|Clostridia,36E2P@31979|Clostridiaceae	186801|Clostridia	M	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose	rfbD	-	1.1.1.133,5.1.3.13	ko:K00067,ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777,R06514	RC00182,RC01531	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
k141_1054_26	655812.HMPREF0061_0444	6.13e-183	512.0	COG1209@1|root,COG1209@2|Bacteria,1V301@1239|Firmicutes,4H9R0@91061|Bacilli	91061|Bacilli	M	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis	rfbA	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
k141_1054_28	1031288.AXAA01000019_gene1062	3.28e-139	418.0	COG0728@1|root,COG0728@2|Bacteria,1TPFI@1239|Firmicutes,247N3@186801|Clostridia,36FH2@31979|Clostridiaceae	186801|Clostridia	S	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane	murJ	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
k141_1054_29	1268239.PALB_11410	1.42e-12	77.4	2DZXJ@1|root,32VMJ@2|Bacteria,1NV9R@1224|Proteobacteria,1SNHS@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_1054_30	1064535.MELS_0816	1.28e-58	194.0	COG1216@1|root,COG1216@2|Bacteria,1V8VN@1239|Firmicutes	1239|Firmicutes	S	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
k141_1054_31	1123307.KB904377_gene325	2.02e-80	251.0	2E54Z@1|root,32ZXX@2|Bacteria,1VGRF@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_1054_32	445961.IW15_06225	2.14e-33	124.0	COG0110@1|root,COG0110@2|Bacteria,4NNQ5@976|Bacteroidetes,1I27N@117743|Flavobacteriia,3ZSVS@59732|Chryseobacterium	976|Bacteroidetes	S	catalyzes the transfer of the O-acetyl moiety to the O antigen	-	-	-	ko:K08280	-	-	-	-	ko00000,ko01000,ko01005	-	-	-	Hexapep,Hexapep_2
k141_1054_33	1540257.JQMW01000011_gene1596	8.63e-172	491.0	COG0451@1|root,COG0451@2|Bacteria,1V34Y@1239|Firmicutes,25EDZ@186801|Clostridia,36F9F@31979|Clostridiaceae	186801|Clostridia	GM	3-beta hydroxysteroid dehydrogenase/isomerase family	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
k141_1054_34	1284686.HMPREF1630_05975	4.45e-84	268.0	COG1215@1|root,COG1215@2|Bacteria,1TPY9@1239|Firmicutes,24E2E@186801|Clostridia,22GKG@1570339|Peptoniphilaceae	186801|Clostridia	M	Glycosyl transferase family 21	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
k141_1054_35	406327.Mevan_0408	6.88e-129	376.0	COG0115@1|root,arCOG02297@2157|Archaea,2XT9V@28890|Euryarchaeota,23QFV@183939|Methanococci	28890|Euryarchaeota	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
k141_1054_36	1139219.I569_02278	1.98e-63	202.0	COG2148@1|root,COG2148@2|Bacteria,1TP7M@1239|Firmicutes,4HCBG@91061|Bacilli,4B0AX@81852|Enterococcaceae	91061|Bacilli	M	Bacterial sugar transferase	-	-	-	ko:K13012,ko:K19428	-	-	-	-	ko00000,ko01000,ko01005	-	-	-	Bac_transf
k141_1054_37	203119.Cthe_2649	3.59e-129	374.0	COG2301@1|root,COG2301@2|Bacteria,1UNWU@1239|Firmicutes,24CR9@186801|Clostridia	186801|Clostridia	C	HpcH/HpaI aldolase/citrate lyase family	-	-	-	-	-	-	-	-	-	-	-	-	HpcH_HpaI
k141_1054_38	1121289.JHVL01000007_gene2818	1.83e-194	592.0	COG3063@1|root,COG3307@1|root,COG3063@2|Bacteria,COG3307@2|Bacteria,1TRQM@1239|Firmicutes,249I7@186801|Clostridia,36FS5@31979|Clostridiaceae	186801|Clostridia	MNU	O-Antigen ligase	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_8,Wzy_C
k141_1054_39	1304284.L21TH_1865	1.73e-109	338.0	COG3206@1|root,COG3206@2|Bacteria,1TSJG@1239|Firmicutes,249MI@186801|Clostridia,36HXB@31979|Clostridiaceae	186801|Clostridia	M	G-rich domain on putative tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GNVR,Wzz
k141_1054_40	1121324.CLIT_4c00070	2.73e-36	150.0	COG5492@1|root,COG5492@2|Bacteria,1VIXQ@1239|Firmicutes,25FMR@186801|Clostridia	186801|Clostridia	N	S-layer homology domain	-	-	-	-	-	-	-	-	-	-	-	-	SLH
k141_1054_41	332101.JIBU02000020_gene1990	5.34e-06	47.0	2DR42@1|root,33A2M@2|Bacteria,1VKCM@1239|Firmicutes,259C5@186801|Clostridia,36P1F@31979|Clostridiaceae	186801|Clostridia	S	Protein of unknown function (DUF2922)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2922
k141_1054_42	935837.JAEK01000020_gene600	2.08e-08	53.1	2DR75@1|root,33AHG@2|Bacteria,1VKH9@1239|Firmicutes,4HR4K@91061|Bacilli,1ZJ6X@1386|Bacillus	91061|Bacilli	S	Protein of unknown function (DUF1659)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1659
k141_1054_45	1304284.L21TH_0521	1.71e-12	63.2	2DT75@1|root,33IZI@2|Bacteria,1U4C1@1239|Firmicutes,24VFM@186801|Clostridia,36U1B@31979|Clostridiaceae	186801|Clostridia	S	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_16
k141_1054_57	445335.CBN_3070	5.34e-59	204.0	2DVYI@1|root,32V0D@2|Bacteria,1VCV5@1239|Firmicutes,24A7F@186801|Clostridia,36GKX@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_1054_61	1449050.JNLE01000005_gene4462	1.47e-10	72.0	COG0791@1|root,COG3103@1|root,COG0791@2|Bacteria,COG3103@2|Bacteria,1UVYK@1239|Firmicutes,249G6@186801|Clostridia,36FW2@31979|Clostridiaceae	186801|Clostridia	M	NLP P60 protein	-	-	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	NLPC_P60,SH3_3
k141_1054_63	552396.HMPREF0863_00269	5.19e-24	117.0	COG5283@1|root,COG5283@2|Bacteria,1UHQM@1239|Firmicutes	1239|Firmicutes	D	Phage tail tape measure protein, TP901 family	-	-	-	-	-	-	-	-	-	-	-	-	PhageMin_Tail,Sipho_tail
k141_1054_74	1487921.DP68_08880	2.34e-41	155.0	COG0338@1|root,COG0338@2|Bacteria,1V1FT@1239|Firmicutes,250FC@186801|Clostridia	186801|Clostridia	L	Putative phage serine protease XkdF	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S78_2
k141_1054_75	1178540.BA70_01780	2.04e-80	265.0	COG5518@1|root,COG5518@2|Bacteria,1TT5R@1239|Firmicutes,4HEHM@91061|Bacilli,1ZE9D@1386|Bacillus	91061|Bacilli	S	portal protein	yqbA	-	-	-	-	-	-	-	-	-	-	-	Phage_portal
k141_1054_78	720555.BATR1942_09785	3.24e-21	90.1	COG4824@1|root,COG4824@2|Bacteria,1V3TR@1239|Firmicutes,4HQ4R@91061|Bacilli	91061|Bacilli	S	phage lysis holin	-	-	-	-	-	-	-	-	-	-	-	-	Phage_holin_4_1
k141_1054_81	1145276.T479_01700	4.08e-17	78.6	2DQ74@1|root,3351A@2|Bacteria,1UNGY@1239|Firmicutes,4IUDZ@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_1054_82	318464.IO99_13680	7.29e-45	164.0	COG3299@1|root,COG3299@2|Bacteria,1TQZU@1239|Firmicutes,249WP@186801|Clostridia,36FT3@31979|Clostridiaceae	186801|Clostridia	S	Baseplate J-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Baseplate_J
k141_1054_83	1002809.SSIL_1436	4.62e-20	87.8	COG3628@1|root,COG3628@2|Bacteria,1VFFX@1239|Firmicutes	1239|Firmicutes	S	Protein of unknown function (DUF2634)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2634
k141_1787_2	338966.Ppro_0051	1.25e-70	225.0	COG0421@1|root,COG0421@2|Bacteria,1RJQS@1224|Proteobacteria	1224|Proteobacteria	E	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_149_1	1232437.KL662020_gene740	1.89e-96	295.0	COG0104@1|root,COG0104@2|Bacteria,1MU5B@1224|Proteobacteria,42M9E@68525|delta/epsilon subdivisions,2WJ3F@28221|Deltaproteobacteria,2MI7I@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
k141_5134_1	1410653.JHVC01000032_gene1037	8.18e-44	162.0	COG5492@1|root,COG5492@2|Bacteria,1W2KG@1239|Firmicutes,24FQ5@186801|Clostridia,36E2B@31979|Clostridiaceae	186801|Clostridia	N	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_5134_2	1410653.JHVC01000032_gene1037	3.69e-82	263.0	COG5492@1|root,COG5492@2|Bacteria,1W2KG@1239|Firmicutes,24FQ5@186801|Clostridia,36E2B@31979|Clostridiaceae	186801|Clostridia	N	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_5135_1	1122207.MUS1_14865	4.18e-09	61.2	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RQ69@1236|Gammaproteobacteria,1XJ95@135619|Oceanospirillales	135619|Oceanospirillales	NT	chemotaxis	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal
k141_1788_1	1157490.EL26_10905	3.75e-73	235.0	COG2357@1|root,COG2357@2|Bacteria,1TQ2F@1239|Firmicutes,4HIW3@91061|Bacilli	91061|Bacilli	S	Region found in RelA / SpoT proteins	-	-	-	-	-	-	-	-	-	-	-	-	RelA_SpoT
k141_1789_2	223926.28809784	1.19e-25	104.0	COG2130@1|root,COG2130@2|Bacteria,1MUC2@1224|Proteobacteria,1RNGM@1236|Gammaproteobacteria,1XT12@135623|Vibrionales	135623|Vibrionales	S	NADP-dependent oxidoreductases	-	-	-	ko:K07119	-	-	-	-	ko00000	-	-	-	ADH_N_2,ADH_zinc_N
k141_5137_1	929562.Emtol_0612	1.42e-13	73.9	COG1083@1|root,COG1083@2|Bacteria,4NM98@976|Bacteroidetes,47JB8@768503|Cytophagia	976|Bacteroidetes	M	CMP-N-acetylneuraminic acid synthetase	pseF	-	-	-	-	-	-	-	-	-	-	-	CTP_transf_3
k141_4476_1	617140.AJZE01000010_gene3603	2.03e-111	324.0	COG0164@1|root,COG0164@2|Bacteria,1RA65@1224|Proteobacteria,1RQ4B@1236|Gammaproteobacteria,1XSNB@135623|Vibrionales	135623|Vibrionales	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhB	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
k141_4476_2	945543.VIBR0546_19854	3.42e-206	578.0	COG0763@1|root,COG0763@2|Bacteria,1MVBI@1224|Proteobacteria,1RNS1@1236|Gammaproteobacteria,1XSUV@135623|Vibrionales	135623|Vibrionales	M	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxB	GO:0003674,GO:0003824,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008194,GO:0008289,GO:0008610,GO:0008654,GO:0008915,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	2.4.1.182	ko:K00748	ko00540,ko01100,map00540,map01100	M00060	R04606	RC00005,RC00059	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT19	-	LpxB
k141_4476_5	1116375.VEJY3_12025	6.51e-127	374.0	COG1044@1|root,COG1044@2|Bacteria,1MUX6@1224|Proteobacteria,1RNYI@1236|Gammaproteobacteria,1XSDH@135623|Vibrionales	135623|Vibrionales	I	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxD	GO:0003674,GO:0003824,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016746,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	2.3.1.191	ko:K02536	ko00540,ko01100,map00540,map01100	M00060	R04550	RC00039,RC00166	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hexapep,Hexapep_2,LpxD
k141_4476_6	1348635.BBJY01000002_gene3435	2.26e-63	199.0	COG2825@1|root,COG2825@2|Bacteria,1RD8X@1224|Proteobacteria,1RQIE@1236|Gammaproteobacteria,1XUST@135623|Vibrionales	135623|Vibrionales	M	Molecular chaperone that interacts specifically with outer membrane proteins, thus maintaining the solubility of early folding intermediates during passage through the periplasm	skp	GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944	-	ko:K06142	-	-	-	-	ko00000	-	-	-	OmpH
k141_4476_7	1219077.VAZ01S_031_00610	3.16e-81	263.0	COG4775@1|root,COG4775@2|Bacteria,1MU0D@1224|Proteobacteria,1RMAP@1236|Gammaproteobacteria,1XTPE@135623|Vibrionales	135623|Vibrionales	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamA	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
k141_4476_8	1348635.BBJY01000002_gene3436	3.41e-96	303.0	COG4775@1|root,COG4775@2|Bacteria,1MU0D@1224|Proteobacteria,1RMAP@1236|Gammaproteobacteria,1XTPE@135623|Vibrionales	135623|Vibrionales	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamA	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
k141_461_1	1116375.VEJY3_20376	0.0	978.0	COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,1RMNZ@1236|Gammaproteobacteria,1XUS0@135623|Vibrionales	1236|Gammaproteobacteria	F	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	-	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
k141_461_2	1116375.VEJY3_20381	0.0	1048.0	COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,1MU5R@1224|Proteobacteria,1S02D@1236|Gammaproteobacteria,1Y3B1@135623|Vibrionales	135623|Vibrionales	C	Dehydrogenase E1 component	-	-	1.2.4.4	ko:K11381	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
k141_150_1	1280001.BAOA01000181_gene2913	8.59e-06	48.1	COG2885@1|root,COG2885@2|Bacteria,1R8DG@1224|Proteobacteria,1RP3K@1236|Gammaproteobacteria,1XV6K@135623|Vibrionales	135623|Vibrionales	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
k141_150_2	345073.VC395_1739	3.28e-176	507.0	COG1538@1|root,COG1538@2|Bacteria,1MYX2@1224|Proteobacteria,1RNX1@1236|Gammaproteobacteria,1XT4S@135623|Vibrionales	135623|Vibrionales	MU	COG1538 Outer membrane protein	-	-	-	ko:K12543	-	M00330	-	-	ko00000,ko00002,ko02000,ko02044	1.B.17,3.A.1.109.4	-	-	OEP
k141_150_3	411154.GFO_1836	2.46e-17	90.5	COG1520@1|root,COG2304@1|root,COG2911@1|root,COG3209@1|root,COG1520@2|Bacteria,COG2304@2|Bacteria,COG2911@2|Bacteria,COG3209@2|Bacteria,4PKBQ@976|Bacteroidetes,1IJ7S@117743|Flavobacteriia	976|Bacteroidetes	M	SPTR CHU large protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Calx-beta,DUF11,HYR,SprB
k141_4814_1	1348635.BBJY01000039_gene16	5.54e-188	542.0	COG1195@1|root,COG3593@1|root,COG1195@2|Bacteria,COG3593@2|Bacteria,1N2CB@1224|Proteobacteria,1RQN2@1236|Gammaproteobacteria,1XY36@135623|Vibrionales	135623|Vibrionales	L	AAA ATPase domain	-	-	-	ko:K07459	-	-	-	-	ko00000	-	-	-	AAA_15
k141_4814_2	595494.Tola_1220	0.0	1082.0	COG0286@1|root,COG0286@2|Bacteria,1MW3A@1224|Proteobacteria,1RMRA@1236|Gammaproteobacteria,1Y4ZH@135624|Aeromonadales	135624|Aeromonadales	V	HsdM N-terminal domain	-	-	2.1.1.72	ko:K03427	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HsdM_N,N6_Mtase
k141_4814_3	1504981.KO116_1740	1.81e-186	525.0	COG4804@1|root,COG4804@2|Bacteria,1NBWK@1224|Proteobacteria,1RY9R@1236|Gammaproteobacteria,1XH7A@135619|Oceanospirillales	135619|Oceanospirillales	S	Protein of unknown function (DUF1016)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1016
k141_4814_4	29495.EA26_20355	2.05e-95	297.0	COG0732@1|root,COG0732@2|Bacteria,1MXSQ@1224|Proteobacteria,1S320@1236|Gammaproteobacteria,1XXDQ@135623|Vibrionales	135623|Vibrionales	V	COG0732 Restriction endonuclease S subunits	-	-	3.1.21.3	ko:K01154	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	Methylase_S
k141_4814_5	870967.VIS19158_04271	6.97e-146	422.0	2BU9N@1|root,32PJ5@2|Bacteria,1Q497@1224|Proteobacteria,1TIFV@1236|Gammaproteobacteria,1XZK3@135623|Vibrionales	135623|Vibrionales	S	FRG	-	-	-	-	-	-	-	-	-	-	-	-	FRG
k141_151_1	234267.Acid_2186	6.12e-11	66.6	COG3386@1|root,COG3386@2|Bacteria,3Y3S3@57723|Acidobacteria	57723|Acidobacteria	G	PFAM NHL repeat containing protein	-	-	-	ko:K13735	ko05100,map05100	-	-	-	ko00000,ko00001	-	-	-	NHL
k141_4913_17	697303.Thewi_1098	1.42e-116	344.0	COG1023@1|root,COG1023@2|Bacteria,1UHN4@1239|Firmicutes,25E7N@186801|Clostridia,42EW4@68295|Thermoanaerobacterales	186801|Clostridia	C	TIGRFAM 6-phosphogluconate dehydrogenase	gnd	-	1.1.1.343,1.1.1.44	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	M00004,M00006	R01528,R10221	RC00001,RC00539	ko00000,ko00001,ko00002,ko01000	-	-	-	6PGD,NAD_binding_2
k141_4913_18	1121324.CLIT_23c04760	6.55e-119	355.0	COG0726@1|root,COG0726@2|Bacteria,1TRUR@1239|Firmicutes,24D1N@186801|Clostridia	186801|Clostridia	G	PFAM Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
k141_4913_19	1286171.EAL2_c09410	1.68e-159	458.0	COG2070@1|root,COG2070@2|Bacteria,1TPX1@1239|Firmicutes,247YZ@186801|Clostridia,25VI7@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	NMO
k141_4913_20	572544.Ilyop_0596	3.78e-180	514.0	COG2195@1|root,COG2195@2|Bacteria,3783C@32066|Fusobacteria	32066|Fusobacteria	E	Cleaves the N-terminal amino acid of tripeptides	pepT	-	3.4.11.4	ko:K01258	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M42
k141_4913_21	986075.CathTA2_0248	4.68e-18	78.6	COG3326@1|root,COG3326@2|Bacteria	2|Bacteria	L	Membrane	ysdA	-	-	-	-	-	-	-	-	-	-	-	CSD,DUF1294
k141_4913_22	709032.Sulku_1324	5.68e-07	57.8	COG2199@1|root,COG3706@2|Bacteria,1NY4T@1224|Proteobacteria,42YUI@68525|delta/epsilon subdivisions,2YR50@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	TIGRFAM diguanylate cyclase (GGDEF) domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
k141_1896_1	1121285.AUFK01000013_gene2051	4.07e-14	72.8	COG0110@1|root,COG0110@2|Bacteria,4NHX5@976|Bacteroidetes,1IIUK@117743|Flavobacteriia	976|Bacteroidetes	S	Hexapeptide repeat of succinyl-transferase	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
k141_1896_2	1499967.BAYZ01000041_gene2336	6.35e-50	166.0	COG1811@1|root,COG1811@2|Bacteria,2NPEK@2323|unclassified Bacteria	2|Bacteria	S	Protein of unknown function (DUF554)	ydfK	-	-	ko:K07150	-	-	-	-	ko00000	-	-	-	DUF554
k141_4595_1	13333.ERN06333	0.000615	47.4	COG0494@1|root,KOG2839@2759|Eukaryota,37U0R@33090|Viridiplantae,3GCVZ@35493|Streptophyta	35493|Streptophyta	T	Nudix hydrolase	-	GO:0003674,GO:0003824,GO:0004551,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005739,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0034432,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464	3.6.1.52	ko:K07766	-	-	-	-	ko00000,ko01000	-	-	-	NUDIX
k141_1496_1	96561.Dole_2048	1.86e-38	152.0	COG3209@1|root,COG3209@2|Bacteria,1MVV1@1224|Proteobacteria,42Q3J@68525|delta/epsilon subdivisions,2WP5U@28221|Deltaproteobacteria,2MKDQ@213118|Desulfobacterales	28221|Deltaproteobacteria	M	TIGRFAM YD repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	RHS_repeat,YwqJ-deaminase
k141_1897_1	571.MC52_16685	8.68e-98	300.0	COG1129@1|root,COG1129@2|Bacteria,1MU22@1224|Proteobacteria,1RMCH@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	import. Responsible for energy coupling to the transport system	rbsA	-	3.6.3.17	ko:K02056,ko:K10441,ko:K10542,ko:K10545,ko:K10551,ko:K10562,ko:K17204,ko:K17215	ko02010,map02010	M00212,M00214,M00215,M00217,M00220,M00221,M00590,M00593	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2,3.A.1.2.1,3.A.1.2.11,3.A.1.2.13,3.A.1.2.16,3.A.1.2.19,3.A.1.2.3,3.A.1.2.4,3.A.1.2.6,3.A.1.2.9	-	-	ABC_tran
k141_4596_1	207559.Dde_2160	1.61e-25	102.0	COG4446@1|root,COG4446@2|Bacteria,1N7IZ@1224|Proteobacteria,42V21@68525|delta/epsilon subdivisions,2WRFF@28221|Deltaproteobacteria,2MCVG@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF1499)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1499
k141_4596_2	1501230.ET33_08340	1.5e-09	58.9	COG5018@1|root,COG5018@2|Bacteria,1VGWS@1239|Firmicutes,4HQT0@91061|Bacilli,26VQ3@186822|Paenibacillaceae	91061|Bacilli	L	DNA polymerase III	exoN1	-	-	-	-	-	-	-	-	-	-	-	RNase_T
k141_4210_1	243277.VC_A0699	5.76e-226	630.0	COG0448@1|root,COG0448@2|Bacteria,1MVTC@1224|Proteobacteria,1RP04@1236|Gammaproteobacteria,1XTGB@135623|Vibrionales	135623|Vibrionales	H	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans	glgC2	GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0008878,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016772,GO:0016779,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0055114,GO:0070566,GO:0071704,GO:1901576	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
k141_4210_2	945550.VISI1226_21194	5.89e-86	255.0	COG1803@1|root,COG1803@2|Bacteria,1RD3D@1224|Proteobacteria,1S3XN@1236|Gammaproteobacteria,1XV9M@135623|Vibrionales	135623|Vibrionales	G	Methylglyoxal synthase	mgsA	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0008150,GO:0008152,GO:0008929,GO:0009058,GO:0009438,GO:0009987,GO:0016829,GO:0016835,GO:0016838,GO:0019242,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0071704,GO:1901576	4.2.3.3	ko:K01734	ko00640,ko01120,map00640,map01120	-	R01016	RC00424	ko00000,ko00001,ko01000	-	-	-	MGS
k141_4210_3	796620.VIBC2010_04914	2.11e-33	128.0	COG0210@1|root,COG0210@2|Bacteria,1MVWI@1224|Proteobacteria,1RN1N@1236|Gammaproteobacteria,1XTAF@135623|Vibrionales	135623|Vibrionales	L	COG0210 Superfamily I DNA and RNA helicases	helD	-	3.6.4.12	ko:K03658	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	Helicase_IV_N,UvrD-helicase,UvrD_C
k141_1497_1	338963.Pcar_3048	3.62e-64	202.0	2A70U@1|root,30VW1@2|Bacteria,1RGBZ@1224|Proteobacteria,42VYK@68525|delta/epsilon subdivisions,2WSFU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Glyoxalase-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase_3
k141_1898_1	1158345.JNLL01000001_gene670	1.27e-40	153.0	COG1353@1|root,COG1353@2|Bacteria	2|Bacteria	J	crispr-associated protein	-	-	2.7.7.19	ko:K00970,ko:K07016	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko02048,ko03019	-	-	-	-
k141_1898_2	1209989.TepiRe1_0130	6.48e-21	91.3	COG1337@1|root,COG1337@2|Bacteria,1V7HY@1239|Firmicutes,24DW1@186801|Clostridia,42FDF@68295|Thermoanaerobacterales	186801|Clostridia	L	RAMP superfamily	-	-	-	ko:K19134	-	-	-	-	ko00000,ko02048	-	-	-	RAMPs
k141_4211_1	857087.Metme_2300	2.26e-121	373.0	COG1196@1|root,COG1401@1|root,COG1196@2|Bacteria,COG1401@2|Bacteria,1NX8Q@1224|Proteobacteria,1T1CA@1236|Gammaproteobacteria	1236|Gammaproteobacteria	V	GTPase subunit of restriction	-	-	-	-	-	-	-	-	-	-	-	-	AAA_5
k141_2198_1	617140.AJZE01000101_gene3119	4.35e-66	214.0	COG0811@1|root,COG0811@2|Bacteria,1MX5J@1224|Proteobacteria,1RMSA@1236|Gammaproteobacteria,1Y2IJ@135623|Vibrionales	135623|Vibrionales	U	MotA/TolQ/ExbB proton channel family	-	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
k141_2198_2	55601.VANGNB10_cI1315c	1.18e-73	226.0	COG0811@1|root,COG0811@2|Bacteria,1MX60@1224|Proteobacteria,1RRX1@1236|Gammaproteobacteria,1XT9X@135623|Vibrionales	135623|Vibrionales	U	TonB system transport protein	exbB3	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
k141_2198_3	945543.VIBR0546_00705	1.29e-69	212.0	COG0848@1|root,COG0848@2|Bacteria,1RI4M@1224|Proteobacteria,1S7MF@1236|Gammaproteobacteria,1XWYC@135623|Vibrionales	135623|Vibrionales	U	COG0848 Biopolymer transport protein	exbD2	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
k141_2198_4	796620.VIBC2010_10497	2.65e-37	135.0	COG0810@1|root,COG0810@2|Bacteria,1R4VE@1224|Proteobacteria,1RQPV@1236|Gammaproteobacteria,1XTNF@135623|Vibrionales	135623|Vibrionales	U	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	tonB	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
k141_2198_5	55601.VANGNB10_cI1312c	2.2e-33	128.0	COG0457@1|root,COG0457@2|Bacteria,1MVH9@1224|Proteobacteria,1S3PV@1236|Gammaproteobacteria,1XTJS@135623|Vibrionales	135623|Vibrionales	S	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,TPR_16,TPR_19,TPR_8
k141_4597_1	1238450.VIBNISOn1_920036	4.81e-33	124.0	28R69@1|root,2ZDKA@2|Bacteria,1P5DZ@1224|Proteobacteria,1SW5A@1236|Gammaproteobacteria,1XWIU@135623|Vibrionales	135623|Vibrionales	S	COG2207 AraC-type DNA-binding domain-containing proteins	VPA0415	-	-	-	-	-	-	-	-	-	-	-	AraC_binding
k141_1899_1	642227.HA49_13615	3.42e-17	80.5	COG0500@1|root,COG0500@2|Bacteria,1MVSK@1224|Proteobacteria,1RMQY@1236|Gammaproteobacteria,4BUE5@82986|Tatumella	1236|Gammaproteobacteria	J	Catalyzes carboxymethyl transfer from carboxy-S- adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs	cmoB	GO:0002097,GO:0002098,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016740,GO:0016741,GO:0016765,GO:0022607,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043170,GO:0043412,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:0090304,GO:1901360	-	ko:K15257	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_9
k141_4598_1	1121396.KB892935_gene3826	4.84e-23	96.7	COG0726@1|root,COG0726@2|Bacteria,1PJQG@1224|Proteobacteria,42W09@68525|delta/epsilon subdivisions,2WRB8@28221|Deltaproteobacteria,2MN9S@213118|Desulfobacterales	28221|Deltaproteobacteria	G	Polysaccharide deacetylase	-	-	3.5.1.104	ko:K22278	-	-	-	-	ko00000,ko01000	-	-	-	Polysacc_deac_1
k141_4598_2	879212.DespoDRAFT_01374	1.65e-66	211.0	COG0535@1|root,COG0535@2|Bacteria,1R5RB@1224|Proteobacteria,42NU3@68525|delta/epsilon subdivisions,2WJ27@28221|Deltaproteobacteria,2MJDN@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Iron-sulfur cluster-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Fer4_14,Radical_SAM,SPASM
k141_1498_1	439235.Dalk_1172	1.24e-21	87.8	COG1917@1|root,COG1917@2|Bacteria,1RDGQ@1224|Proteobacteria,42U6Z@68525|delta/epsilon subdivisions,2WQZN@28221|Deltaproteobacteria,2MNDS@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Catalyzes the circularization of gamma-N-acetyl- alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6- tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant	ectC	-	4.2.1.108	ko:K06720	ko00260,ko01100,ko01120,map00260,map01100,map01120	M00033	R06979	RC01729	ko00000,ko00001,ko00002,ko01000	-	-	-	Ectoine_synth
k141_4213_1	1304885.AUEY01000011_gene1735	9.76e-47	172.0	COG1924@1|root,COG3580@1|root,COG3581@1|root,COG1924@2|Bacteria,COG3580@2|Bacteria,COG3581@2|Bacteria,1PKG6@1224|Proteobacteria,42MY4@68525|delta/epsilon subdivisions,2WJFI@28221|Deltaproteobacteria,2MIP0@213118|Desulfobacterales	68525|delta/epsilon subdivisions	I	BadF BadG BcrA BcrD	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG,DUF2229
k141_1232_1	1121396.KB893052_gene3417	9.44e-144	429.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,43BR8@68525|delta/epsilon subdivisions,2X724@28221|Deltaproteobacteria,2MPMS@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Sigma-54 interaction domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Sigma54_activat
k141_1232_2	1304885.AUEY01000013_gene3114	1.01e-214	602.0	COG0527@1|root,COG0527@2|Bacteria,1MW3H@1224|Proteobacteria,42NDT@68525|delta/epsilon subdivisions,2WIWZ@28221|Deltaproteobacteria,2MI35@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Belongs to the aspartokinase family	lysC	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT,ACT_7
k141_1232_3	1157708.KB907450_gene6500	1.49e-12	68.2	COG0802@1|root,COG0802@2|Bacteria,1RGYU@1224|Proteobacteria,2VSJY@28216|Betaproteobacteria,4AEJQ@80864|Comamonadaceae	28216|Betaproteobacteria	S	Threonylcarbamoyl adenosine biosynthesis protein TsaE	yjeE	-	-	ko:K06925	-	-	-	-	ko00000,ko03016	-	-	-	TsaE
k141_2199_2	96561.Dole_2210	2.29e-62	213.0	COG0823@1|root,COG0823@2|Bacteria,1MV09@1224|Proteobacteria,42PHP@68525|delta/epsilon subdivisions,2WIXN@28221|Deltaproteobacteria,2MHR4@213118|Desulfobacterales	28221|Deltaproteobacteria	U	Involved in the TonB-independent uptake of proteins	tolB	GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0019534,GO:0022857,GO:0051179,GO:0051234,GO:0055085,GO:1901998	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40,TolB_N
k141_4599_1	675813.VIB_002241	6.73e-144	410.0	COG1349@1|root,COG1349@2|Bacteria,1QM4U@1224|Proteobacteria,1RNN2@1236|Gammaproteobacteria,1XSWP@135623|Vibrionales	135623|Vibrionales	K	transcriptional	ulaR	-	-	ko:K03477	-	-	-	-	ko00000,ko03000	-	-	-	DeoRC,HTH_DeoR
k141_1501_2	3641.EOY06147	1.08e-14	74.7	COG2230@1|root,2QSMW@2759|Eukaryota,37NYG@33090|Viridiplantae,3GBIW@35493|Streptophyta	35493|Streptophyta	M	synthase	-	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006629,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0008825,GO:0009987,GO:0016740,GO:0016741,GO:0030258,GO:0032259,GO:0044237,GO:0044238,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0071704	2.1.1.79	ko:K00574	-	-	-	-	ko00000,ko01000	-	-	-	Amino_oxidase,CMAS,NAD_binding_8
k141_248_1	1121441.AUCX01000001_gene2619	2.53e-227	635.0	COG0247@1|root,COG0247@2|Bacteria,1MWTK@1224|Proteobacteria,42MMF@68525|delta/epsilon subdivisions,2WJ1F@28221|Deltaproteobacteria,2M8PG@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	4Fe-4S ferredoxin iron-sulfur binding domain protein	-	-	-	ko:K11473	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001	-	-	-	CCG,Fer4_8
k141_248_2	1121441.AUCX01000001_gene2620	2.91e-274	757.0	COG0277@1|root,COG0277@2|Bacteria,1MU6Y@1224|Proteobacteria,42M0V@68525|delta/epsilon subdivisions,2WIQ1@28221|Deltaproteobacteria,2M8WK@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	PFAM FAD linked oxidase domain protein	glcD	-	1.1.3.15	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
k141_248_3	1121441.AUCX01000001_gene2621	0.0	902.0	COG1620@1|root,COG1620@2|Bacteria,1MV13@1224|Proteobacteria,42NEP@68525|delta/epsilon subdivisions,2WIVJ@28221|Deltaproteobacteria,2M860@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	PFAM L-lactate permease	-	-	-	ko:K03303	-	-	-	-	ko00000,ko02000	2.A.14	-	-	Lactate_perm
k141_4600_1	349965.yinte0001_36400	5.7e-13	68.2	COG4213@1|root,COG4213@2|Bacteria,1MX63@1224|Proteobacteria,1RRJ3@1236|Gammaproteobacteria,41EWK@629|Yersinia	1236|Gammaproteobacteria	G	xylF D-xylose ABC transporter, D-xylose-binding protein	xylF	GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005975,GO:0005996,GO:0006810,GO:0008150,GO:0008152,GO:0008643,GO:0015749,GO:0015750,GO:0015753,GO:0019321,GO:0030246,GO:0030288,GO:0030313,GO:0031975,GO:0034219,GO:0036094,GO:0042597,GO:0042732,GO:0044238,GO:0044281,GO:0044464,GO:0048029,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071704	-	ko:K10543	ko02010,map02010	M00215	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.4	-	iB21_1397.B21_03369,iECBD_1354.ECBD_0168,iECD_1391.ECD_03418,iEcHS_1320.EcHS_A3769,iEcolC_1368.EcolC_0148,iUTI89_1310.UTI89_C4107,ic_1306.c4386	Peripla_BP_4
k141_1233_1	1278307.KB907003_gene371	9.35e-94	297.0	COG1012@1|root,COG1454@1|root,COG1012@2|Bacteria,COG1454@2|Bacteria,1MVPH@1224|Proteobacteria,1RNBH@1236|Gammaproteobacteria,2QHWH@267894|Psychromonadaceae	1236|Gammaproteobacteria	C	belongs to the iron- containing alcohol dehydrogenase family	adhE	GO:0003674,GO:0003824,GO:0004022,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006067,GO:0006115,GO:0008150,GO:0008152,GO:0008774,GO:0009058,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0016620,GO:0016903,GO:0016999,GO:0017000,GO:0017144,GO:0034308,GO:0034309,GO:0042802,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0055114,GO:0071704,GO:1901576,GO:1901615,GO:1901617	1.1.1.1,1.2.1.10	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	-	R00228,R00623,R00754,R01172,R04880,R05233,R05234,R06917,R06927	RC00004,RC00050,RC00088,RC00099,RC00116,RC00184,RC00649,RC01195	ko00000,ko00001,ko01000	-	-	iEcE24377_1341.EcE24377A_1389,iYL1228.KPN_02199	Aldedh,Fe-ADH
k141_2201_1	393595.ABO_2515	2.36e-47	163.0	COG0385@1|root,COG0385@2|Bacteria,1MXF3@1224|Proteobacteria,1RNZF@1236|Gammaproteobacteria,1XHYJ@135619|Oceanospirillales	135619|Oceanospirillales	S	Bile acid sodium symporter	-	-	-	ko:K03453	-	-	-	-	ko00000	2.A.28	-	-	SBF
k141_1502_1	1304885.AUEY01000003_gene445	1.79e-106	339.0	COG0210@1|root,COG1379@1|root,COG0210@2|Bacteria,COG1379@2|Bacteria,1MU0G@1224|Proteobacteria,42MKU@68525|delta/epsilon subdivisions,2WJR3@28221|Deltaproteobacteria,2MIS3@213118|Desulfobacterales	28221|Deltaproteobacteria	L	PFAM UvrD REP helicase	-	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
k141_3896_2	318167.Sfri_0400	6.96e-81	251.0	2BWY8@1|root,32F2N@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_3896_3	1248232.BANQ01000155_gene4176	1.59e-231	660.0	COG1384@1|root,COG1384@2|Bacteria,1R33M@1224|Proteobacteria,1T62P@1236|Gammaproteobacteria,1Y0P0@135623|Vibrionales	135623|Vibrionales	J	Domain of unknown function (DUF4209)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4209
k141_3896_4	945550.VISI1226_05828	3.77e-102	320.0	COG0582@1|root,COG0582@2|Bacteria,1N73Z@1224|Proteobacteria,1SEHI@1236|Gammaproteobacteria,1XTD7@135623|Vibrionales	135623|Vibrionales	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
k141_3896_6	1219065.VPR01S_06_00310	1.62e-112	328.0	COG2030@1|root,COG2030@2|Bacteria,1RAHS@1224|Proteobacteria,1T0EH@1236|Gammaproteobacteria,1XTU1@135623|Vibrionales	135623|Vibrionales	I	COG2030 Acyl dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
k141_3896_7	998088.B565_1702	2.5e-32	139.0	COG0840@1|root,COG4564@1|root,COG0840@2|Bacteria,COG4564@2|Bacteria,1MU9B@1224|Proteobacteria,1RMV2@1236|Gammaproteobacteria,1Y3WT@135624|Aeromonadales	135624|Aeromonadales	NT	Cache_2	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal,sCache_2
k141_3896_8	1219065.VPR01S_06_00320	9.68e-114	335.0	COG0226@1|root,COG0226@2|Bacteria,1MW2Z@1224|Proteobacteria,1S5B9@1236|Gammaproteobacteria,1XTQY@135623|Vibrionales	135623|Vibrionales	P	COG0226 ABC-type phosphate transport system, periplasmic component	-	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like,PBP_like_2
k141_3896_9	675814.VIC_002670	1.08e-43	145.0	2AWCE@1|root,31N87@2|Bacteria,1QJZK@1224|Proteobacteria,1TI21@1236|Gammaproteobacteria,1XY73@135623|Vibrionales	135623|Vibrionales	S	Protein of unknown function (DUF3024)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3024
k141_3896_10	675814.VIC_002798	8.73e-115	333.0	COG3155@1|root,COG3155@2|Bacteria,1MW2K@1224|Proteobacteria,1RMDJ@1236|Gammaproteobacteria,1XVK8@135623|Vibrionales	135623|Vibrionales	Q	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate	elbB	-	-	-	-	-	-	-	-	-	-	-	DJ-1_PfpI
k141_3896_11	1219077.VAZ01S_049_00220	1.41e-44	156.0	COG2188@1|root,COG2188@2|Bacteria,1R4PN@1224|Proteobacteria,1RQ87@1236|Gammaproteobacteria,1XT3H@135623|Vibrionales	135623|Vibrionales	K	COG2188 Transcriptional regulators	phnR	-	-	-	-	-	-	-	-	-	-	-	GntR,UTRA
k141_3896_12	617140.AJZE01000093_gene2474	2.81e-63	203.0	2E047@1|root,32VSV@2|Bacteria,1RK11@1224|Proteobacteria,1S49N@1236|Gammaproteobacteria,1XXG7@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_3896_13	1219065.VPR01S_05_01290	3.49e-225	636.0	COG4166@1|root,COG4166@2|Bacteria,1MUVU@1224|Proteobacteria,1RMA1@1236|Gammaproteobacteria,1XUMM@135623|Vibrionales	135623|Vibrionales	E	ABC-type oligopeptide transport system, periplasmic component	-	-	-	ko:K13893	ko02010,map02010	M00349	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.21,3.A.1.5.24	-	-	SBP_bac_5
k141_249_1	1283284.AZUK01000001_gene271	1.48e-190	545.0	COG1538@1|root,COG1538@2|Bacteria,1MUZZ@1224|Proteobacteria,1RQEP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	MU	RND efflux system, outer membrane lipoprotein	mdtP	-	-	-	-	-	-	-	-	-	-	-	OEP
k141_4214_1	870967.VIS19158_05743	1.22e-35	130.0	COG1403@1|root,COG1403@2|Bacteria,1RATU@1224|Proteobacteria,1S3B3@1236|Gammaproteobacteria,1Y2AA@135623|Vibrionales	135623|Vibrionales	L	HNH endonuclease	-	-	-	ko:K07451	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	-
k141_2204_1	1348635.BBJY01000004_gene3091	2.18e-15	75.1	2BWZZ@1|root,2Z86E@2|Bacteria,1MW89@1224|Proteobacteria,1S85K@1236|Gammaproteobacteria,1XTRX@135623|Vibrionales	135623|Vibrionales	S	Protein of unknown function (DUF2927)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2927
k141_2204_2	1191299.AJYX01000067_gene3852	2.21e-25	102.0	COG0390@1|root,COG0390@2|Bacteria,1MV2N@1224|Proteobacteria,1RSGA@1236|Gammaproteobacteria,1XT6E@135623|Vibrionales	135623|Vibrionales	S	transport system, permease component	-	-	-	ko:K02069	-	M00211	-	-	ko00000,ko00002,ko02000	9.B.25.1	-	-	UPF0014
k141_1900_1	204773.HEAR1159	1.34e-16	83.6	COG3547@1|root,COG3547@2|Bacteria,1MUER@1224|Proteobacteria,2VJ5H@28216|Betaproteobacteria,47573@75682|Oxalobacteraceae	28216|Betaproteobacteria	L	Transposase IS116/IS110/IS902 family	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k141_1900_3	675817.VDA_000585	0.000578	47.8	2AXBE@1|root,31PAH@2|Bacteria,1RJC8@1224|Proteobacteria,1S7IN@1236|Gammaproteobacteria,1XZVX@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_1901_1	1565314.OA34_06340	3.4e-25	100.0	COG1871@1|root,COG1871@2|Bacteria,1RAWA@1224|Proteobacteria,42QP1@68525|delta/epsilon subdivisions,2YSY7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis	cheD	-	3.5.1.44	ko:K03411	ko02030,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheD
k141_1504_1	857087.Metme_2302	2.43e-149	455.0	COG0507@1|root,COG1112@1|root,COG0507@2|Bacteria,COG1112@2|Bacteria,1MWW9@1224|Proteobacteria,1RP8R@1236|Gammaproteobacteria,1XGUV@135618|Methylococcales	135618|Methylococcales	L	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_11,AAA_12
k141_1234_1	29495.EA26_17335	0.0	1503.0	COG0587@1|root,COG0587@2|Bacteria,1MUIF@1224|Proteobacteria,1RP0K@1236|Gammaproteobacteria,1XTXD@135623|Vibrionales	135623|Vibrionales	L	COG0587 DNA polymerase III, alpha subunit	dnaE	GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032991,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
k141_3897_2	675813.VIB_001213	2.2e-19	81.3	2AWN3@1|root,31NIV@2|Bacteria,1QK9H@1224|Proteobacteria,1TID0@1236|Gammaproteobacteria,1XYWJ@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_4601_1	674977.VMC_04910	0.0	975.0	COG1164@1|root,COG1164@2|Bacteria,1MUYZ@1224|Proteobacteria,1RYXN@1236|Gammaproteobacteria,1XTZF@135623|Vibrionales	135623|Vibrionales	E	Peptidase family M3	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M3
k141_1235_1	1121935.AQXX01000116_gene5186	3.41e-82	254.0	COG1879@1|root,COG1879@2|Bacteria,1NRXG@1224|Proteobacteria,1RY9X@1236|Gammaproteobacteria,1XHHP@135619|Oceanospirillales	135619|Oceanospirillales	G	PFAM periplasmic binding protein LacI transcriptional regulator	-	-	-	ko:K10552	ko02010,map02010	M00218	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.7	-	-	Peripla_BP_4
k141_1902_1	55601.VANGNB10_cII0812	5.3e-173	514.0	COG2206@1|root,COG3437@1|root,COG2206@2|Bacteria,COG3437@2|Bacteria,1MV37@1224|Proteobacteria,1RM9C@1236|Gammaproteobacteria,1XSHM@135623|Vibrionales	135623|Vibrionales	KT	COG0840 Methyl-accepting chemotaxis protein	-	-	-	-	-	-	-	-	-	-	-	-	HD,HD_5,dCache_1
k141_1902_2	55601.VANGNB10_cII0812	1.55e-13	68.9	COG2206@1|root,COG3437@1|root,COG2206@2|Bacteria,COG3437@2|Bacteria,1MV37@1224|Proteobacteria,1RM9C@1236|Gammaproteobacteria,1XSHM@135623|Vibrionales	135623|Vibrionales	KT	COG0840 Methyl-accepting chemotaxis protein	-	-	-	-	-	-	-	-	-	-	-	-	HD,HD_5,dCache_1
k141_3899_2	1231057.AMGD01000026_gene3083	0.000461	47.0	COG0715@1|root,COG0715@2|Bacteria,1TPAD@1239|Firmicutes,4HBR9@91061|Bacilli,26FWD@186818|Planococcaceae	91061|Bacilli	P	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components	M1-596	-	-	-	-	-	-	-	-	-	-	-	NMT1
k141_2206_3	177437.HRM2_24010	2.48e-114	337.0	COG0489@1|root,COG0489@2|Bacteria,1MU7R@1224|Proteobacteria,42NR0@68525|delta/epsilon subdivisions,2WIPG@28221|Deltaproteobacteria,2MHV5@213118|Desulfobacterales	28221|Deltaproteobacteria	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	-	-	-	-	-	-	-	-	-	-	-	-	ParA
k141_3554_1	1121324.CLIT_24c00030	1.56e-201	579.0	COG2244@1|root,COG2244@2|Bacteria,1TNYX@1239|Firmicutes,2485G@186801|Clostridia,25QTE@186804|Peptostreptococcaceae	186801|Clostridia	S	Stage V sporulation protein B	spoVB	-	-	ko:K06409	-	-	-	-	ko00000,ko02000	2.A.66.2.14	-	-	Polysacc_synt,Polysacc_synt_3,Polysacc_synt_C
k141_3554_2	667014.Thein_1029	5.16e-25	110.0	COG0760@1|root,COG0760@2|Bacteria,2GHMC@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	O	PPIC-type PPIASE domain	-	-	5.2.1.8	ko:K03769	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase_3
k141_3554_3	1151292.QEW_4128	0.0	1221.0	COG1197@1|root,COG1197@2|Bacteria,1TPF1@1239|Firmicutes,248D8@186801|Clostridia,25QCA@186804|Peptostreptococcaceae	186801|Clostridia	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
k141_3554_4	720554.Clocl_0324	1e-79	243.0	COG0193@1|root,COG0193@2|Bacteria,1V3NB@1239|Firmicutes,24HMC@186801|Clostridia,3WIEP@541000|Ruminococcaceae	186801|Clostridia	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	-	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
k141_3554_5	1121324.CLIT_24c00070	3.7e-174	491.0	COG0462@1|root,COG0462@2|Bacteria,1TQ6Q@1239|Firmicutes,248ZN@186801|Clostridia,25QGP@186804|Peptostreptococcaceae	186801|Clostridia	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	prs	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran_N
k141_3554_6	1408823.AXUS01000010_gene1824	9.26e-177	509.0	COG1207@1|root,COG1207@2|Bacteria,1TP88@1239|Firmicutes,248Z3@186801|Clostridia,25QZH@186804|Peptostreptococcaceae	186801|Clostridia	M	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain	glmU	-	2.3.1.157,2.7.7.23	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00362	R00416,R05332	RC00002,RC00004,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,Hexapep_2,NTP_transf_3,NTP_transferase
k141_3554_7	1123009.AUID01000005_gene1607	1.37e-40	136.0	COG2088@1|root,COG2088@2|Bacteria,1V9ZG@1239|Firmicutes,24MVQ@186801|Clostridia,269C7@186813|unclassified Clostridiales	186801|Clostridia	M	Could be involved in septation	spoVG	-	-	ko:K06412	-	-	-	-	ko00000	-	-	-	SpoVG
k141_3554_8	596329.HMPREF0631_1506	6.99e-128	371.0	COG0503@1|root,COG0503@2|Bacteria,1TPN9@1239|Firmicutes,25CKT@186801|Clostridia,25QE2@186804|Peptostreptococcaceae	186801|Clostridia	F	operon repressor	purR	-	-	ko:K09685	-	-	-	-	ko00000,ko03000	-	-	-	Pribosyltran,PuR_N
k141_3554_9	1408823.AXUS01000010_gene1821	1.22e-155	455.0	COG0773@1|root,COG0773@2|Bacteria,1TQ5H@1239|Firmicutes,2484K@186801|Clostridia,25R68@186804|Peptostreptococcaceae	186801|Clostridia	M	Belongs to the MurCDEF family	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
k141_3554_10	309798.COPRO5265_1261	4.3e-08	55.5	2E6A2@1|root,330XY@2|Bacteria,1VISZ@1239|Firmicutes,24QK3@186801|Clostridia,42GYR@68295|Thermoanaerobacterales	186801|Clostridia	S	Coenzyme PQQ synthesis protein D (PqqD)	-	-	-	-	-	-	-	-	-	-	-	-	PqqD
k141_3554_11	445973.CLOBAR_02512	1.62e-106	320.0	COG0053@1|root,COG0053@2|Bacteria,1TSGY@1239|Firmicutes,2491V@186801|Clostridia,25SS5@186804|Peptostreptococcaceae	186801|Clostridia	P	Dimerisation domain of Zinc Transporter	fieF	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
k141_5272_13	298386.PBPRB0040	1.54e-239	663.0	COG0754@1|root,COG0754@2|Bacteria,1MW6V@1224|Proteobacteria,1RQAP@1236|Gammaproteobacteria,1XTKG@135623|Vibrionales	135623|Vibrionales	E	Glutathionylspermidine synthase preATP-grasp	-	-	-	-	-	-	-	-	-	-	-	-	GSP_synth
k141_5272_14	754436.JCM19237_982	6.35e-53	170.0	COG3789@1|root,COG3789@2|Bacteria,1RDFN@1224|Proteobacteria,1S565@1236|Gammaproteobacteria,1XY92@135623|Vibrionales	135623|Vibrionales	S	Uncharacterized protein conserved in bacteria (DUF2170)	-	-	-	ko:K09980	-	-	-	-	ko00000	-	-	-	DUF2170
k141_5272_15	298386.PBPRB0055	3.03e-107	315.0	COG1842@1|root,COG1842@2|Bacteria,1R41V@1224|Proteobacteria,1RPJ9@1236|Gammaproteobacteria,1XWH9@135623|Vibrionales	135623|Vibrionales	KT	PspA/IM30 family	-	-	-	-	-	-	-	-	-	-	-	-	PspA_IM30
k141_5272_16	298386.PBPRB0054	6.62e-171	485.0	COG1226@1|root,COG1226@2|Bacteria,1NT9G@1224|Proteobacteria,1RZME@1236|Gammaproteobacteria,1XTBJ@135623|Vibrionales	135623|Vibrionales	P	COG1226 Kef-type K transport systems	VP1064	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans_2,TrkA_N
k141_5272_17	298386.PBPRB0053	7.24e-90	270.0	28M4V@1|root,2ZAIQ@2|Bacteria,1MV1M@1224|Proteobacteria,1RZDJ@1236|Gammaproteobacteria,1XX2G@135623|Vibrionales	135623|Vibrionales	S	Protein of unknown function (DUF2491)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2491
k141_5272_18	674977.VMC_31770	7.85e-45	150.0	COG3766@1|root,COG3766@2|Bacteria,1N14W@1224|Proteobacteria,1S3T5@1236|Gammaproteobacteria,1XWWB@135623|Vibrionales	135623|Vibrionales	S	Domain of Unknown Function (DUF350)	-	-	-	ko:K08989	-	-	-	-	ko00000	-	-	-	DUF350
k141_5272_19	754436.JCM19237_989	2.05e-74	230.0	COG5463@1|root,COG5463@2|Bacteria,1MXGU@1224|Proteobacteria,1RPEV@1236|Gammaproteobacteria,1Y2RT@135623|Vibrionales	135623|Vibrionales	S	Protein of unknown function (DUF1190)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1190
k141_5272_21	1348635.BBJY01000006_gene381	2.81e-179	523.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1S04U@1236|Gammaproteobacteria,1XVY3@135623|Vibrionales	135623|Vibrionales	NT	Tar ligand binding domain homologue	hlyB	GO:0003674,GO:0005215,GO:0008150,GO:0009405,GO:0044419,GO:0051704	-	-	-	-	-	-	-	-	-	-	4HB_MCP_1,MCPsignal
k141_5273_1	177437.HRM2_36270	1.17e-39	132.0	COG0051@1|root,COG0051@2|Bacteria,1RGWF@1224|Proteobacteria,42SE4@68525|delta/epsilon subdivisions,2WP4K@28221|Deltaproteobacteria,2MK4M@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Involved in the binding of tRNA to the ribosomes	rpsJ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02946	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S10
k141_5273_2	1121405.dsmv_3642	5.16e-75	228.0	COG0049@1|root,COG0049@2|Bacteria,1MXC8@1224|Proteobacteria,42QR7@68525|delta/epsilon subdivisions,2WNFM@28221|Deltaproteobacteria,2MJJG@213118|Desulfobacterales	28221|Deltaproteobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA	rpsG	GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02992	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S7
k141_5273_3	933262.AXAM01000079_gene2200	2.09e-73	222.0	COG0048@1|root,COG0048@2|Bacteria,1RCWY@1224|Proteobacteria,42RDQ@68525|delta/epsilon subdivisions,2WND8@28221|Deltaproteobacteria,2MJVJ@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit	rpsL	-	-	ko:K02950	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosom_S12_S23
k141_2940_1	933262.AXAM01000017_gene3121	2.57e-35	132.0	COG0500@1|root,COG2226@2|Bacteria,1RASQ@1224|Proteobacteria,42QTY@68525|delta/epsilon subdivisions,2WMN2@28221|Deltaproteobacteria,2MJIY@213118|Desulfobacterales	28221|Deltaproteobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
k141_2940_2	96561.Dole_0141	1.59e-24	99.4	COG2172@1|root,COG2172@2|Bacteria,1NDH7@1224|Proteobacteria,43BQG@68525|delta/epsilon subdivisions,2X71J@28221|Deltaproteobacteria,2MM48@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Histidine kinase-like ATPase domain	-	-	2.7.11.1	ko:K04757	-	-	-	-	ko00000,ko01000,ko01001,ko03021	-	-	-	HATPase_c_2
k141_2940_3	1304885.AUEY01000001_gene3291	3.93e-153	443.0	COG0745@1|root,COG2208@1|root,COG0745@2|Bacteria,COG2208@2|Bacteria,1QVDV@1224|Proteobacteria,43BQF@68525|delta/epsilon subdivisions,2X71I@28221|Deltaproteobacteria,2MJBP@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Sigma factor PP2C-like phosphatases	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,SpoIIE
k141_2940_5	1121441.AUCX01000022_gene802	1.3e-145	425.0	COG5438@1|root,COG5438@2|Bacteria,1MYCQ@1224|Proteobacteria,42PF1@68525|delta/epsilon subdivisions,2WM9H@28221|Deltaproteobacteria,2M9JN@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	YibE F family protein	-	-	-	-	-	-	-	-	-	-	-	-	YibE_F
k141_1327_2	458817.Shal_1790	1.52e-52	173.0	COG1961@1|root,COG1961@2|Bacteria,1MXXT@1224|Proteobacteria,1S08N@1236|Gammaproteobacteria,2QCBE@267890|Shewanellaceae	1236|Gammaproteobacteria	L	PFAM Resolvase, N-terminal domain	pin	GO:0000150,GO:0003674,GO:0003824,GO:0006139,GO:0006259,GO:0006310,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140097,GO:1901360	-	ko:K14060	-	-	-	-	ko00000	-	-	-	HTH_7,Resolvase
k141_1327_4	1151116.Q7S_08215	2.98e-74	245.0	COG3378@1|root,COG3378@2|Bacteria,1QVIS@1224|Proteobacteria,1S02S@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Psort location Cytoplasmic, score	-	-	-	ko:K06919	-	-	-	-	ko00000	-	-	-	Prim-Pol,Toprim_3,Toprim_4
k141_5275_1	243277.VC_1416	2.84e-235	687.0	COG3501@1|root,COG3501@2|Bacteria,1MU7Q@1224|Proteobacteria,1RMZS@1236|Gammaproteobacteria,1XUHW@135623|Vibrionales	135623|Vibrionales	M	protein conserved in bacteria	vgrG1	GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0006464,GO:0006807,GO:0006996,GO:0007010,GO:0007015,GO:0008144,GO:0008150,GO:0008152,GO:0008154,GO:0009405,GO:0009987,GO:0016043,GO:0016874,GO:0016879,GO:0016881,GO:0017076,GO:0018149,GO:0018153,GO:0018193,GO:0018199,GO:0018205,GO:0018262,GO:0018995,GO:0019538,GO:0022411,GO:0030029,GO:0030036,GO:0030042,GO:0030430,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032984,GO:0033643,GO:0033646,GO:0035639,GO:0036094,GO:0036211,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0043624,GO:0043656,GO:0043657,GO:0043933,GO:0044215,GO:0044216,GO:0044217,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044419,GO:0046872,GO:0051261,GO:0051704,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:0097435,GO:1901265,GO:1901363,GO:1901564	-	ko:K11904	ko03070,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	ACD,Phage_GPD
k141_5276_1	1265505.ATUG01000001_gene4138	2.25e-42	145.0	COG2062@1|root,COG2062@2|Bacteria,1RGWQ@1224|Proteobacteria,42SEE@68525|delta/epsilon subdivisions,2WPM2@28221|Deltaproteobacteria,2MKBQ@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Phosphohistidine phosphatase SixA	-	-	-	ko:K08296	-	-	-	-	ko00000,ko01000	-	-	-	His_Phos_1
k141_1329_1	338963.Pcar_2634	6.08e-168	484.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,42M2A@68525|delta/epsilon subdivisions,2WJ41@28221|Deltaproteobacteria,43T6U@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	PFAM ABC transporter related	ybiT	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,ABC_tran_Xtn
k141_2036_1	1348635.BBJY01000008_gene1730	9.57e-233	650.0	COG0189@1|root,COG0189@2|Bacteria,1MX5X@1224|Proteobacteria,1RNXP@1236|Gammaproteobacteria,1XW57@135623|Vibrionales	135623|Vibrionales	HJ	Ribosomal protein S6 modification	-	-	-	-	-	-	-	-	-	-	-	-	RLAN,RimK
k141_2036_2	1348635.BBJY01000008_gene1731	6.48e-152	435.0	COG0598@1|root,COG0598@2|Bacteria,1MW8W@1224|Proteobacteria,1RRTZ@1236|Gammaproteobacteria,1XSI8@135623|Vibrionales	135623|Vibrionales	P	COG0598 Mg2 and Co2 transporters	-	-	-	ko:K16074	-	-	-	-	ko00000,ko02000	1.A.35.4	-	-	CorA
k141_2036_3	1051646.VITU9109_25695	2.81e-82	263.0	COG2203@1|root,COG2206@1|root,COG2203@2|Bacteria,COG2206@2|Bacteria,1RAQS@1224|Proteobacteria,1T1XS@1236|Gammaproteobacteria,1XUFB@135623|Vibrionales	135623|Vibrionales	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HD_5
k141_2036_4	1232453.BAIF02000033_gene2665	5.28e-10	66.6	COG2169@1|root,COG2169@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	2.1.1.63,3.2.2.21	ko:K00567,ko:K13529,ko:K15051	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03000,ko03400	-	-	-	Ada_Zn_binding,AlkA_N,AraC_binding,DNA_binding_1,Endonuclea_NS_2,HTH_18
k141_2036_5	345073.VC395_2456	6.66e-172	500.0	COG1022@1|root,COG1022@2|Bacteria,1MU4D@1224|Proteobacteria,1RPNE@1236|Gammaproteobacteria,1XTZV@135623|Vibrionales	135623|Vibrionales	I	COG1022 Long-chain acyl-CoA synthetases (AMP-forming)	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
k141_2036_6	345073.VC395_2456	4.74e-51	177.0	COG1022@1|root,COG1022@2|Bacteria,1MU4D@1224|Proteobacteria,1RPNE@1236|Gammaproteobacteria,1XTZV@135623|Vibrionales	135623|Vibrionales	I	COG1022 Long-chain acyl-CoA synthetases (AMP-forming)	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
k141_2036_7	1348635.BBJY01000008_gene1739	5.48e-28	110.0	COG0457@1|root,COG0457@2|Bacteria,1NFC8@1224|Proteobacteria,1RWMG@1236|Gammaproteobacteria,1XVGU@135623|Vibrionales	135623|Vibrionales	S	COG0457 FOG TPR repeat	VP2409	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_16,TPR_17,TPR_2,TPR_8
k141_1330_1	93220.LV28_10670	2.14e-43	153.0	28KHR@1|root,31E42@2|Bacteria,1QBDS@1224|Proteobacteria,2W7XT@28216|Betaproteobacteria,1KB3H@119060|Burkholderiaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_1330_2	93220.LV28_10665	2.87e-79	260.0	COG4928@1|root,COG4928@2|Bacteria,1MWRP@1224|Proteobacteria,2VIGX@28216|Betaproteobacteria,1KHJK@119060|Burkholderiaceae	28216|Betaproteobacteria	S	KAP family P-loop domain	-	-	-	-	-	-	-	-	-	-	-	-	KAP_NTPase
k141_2037_3	1265505.ATUG01000002_gene1259	8.36e-134	385.0	COG0730@1|root,COG0730@2|Bacteria,1R3V4@1224|Proteobacteria,42NFH@68525|delta/epsilon subdivisions,2WITT@28221|Deltaproteobacteria,2MHQE@213118|Desulfobacterales	28221|Deltaproteobacteria	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
k141_2943_1	911008.GLAD_00884	7.53e-134	384.0	COG4221@1|root,COG4221@2|Bacteria,1MV0A@1224|Proteobacteria,1RSK5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	COG4221 Short-chain alcohol dehydrogenase of	rbtD	-	1.1.1.56	ko:K00039	ko00040,ko01100,map00040,map01100	-	R01895	RC00102	ko00000,ko00001,ko01000	-	-	-	adh_short
k141_2943_2	298386.PBPRB0269	1.58e-126	369.0	COG3623@1|root,COG3623@2|Bacteria,1MWTD@1224|Proteobacteria,1RPT6@1236|Gammaproteobacteria,1XVJF@135623|Vibrionales	135623|Vibrionales	G	3-epimerase	-	-	5.1.3.22	ko:K03079	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	M00550	R03244	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	AP_endonuc_2
k141_2943_3	1238450.VIBNISOn1_1370012	1.28e-200	562.0	COG1063@1|root,COG1063@2|Bacteria,1MV9A@1224|Proteobacteria,1RMNY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate	gutB	-	1.1.1.14	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	M00014	R00875,R01896	RC00085,RC00102	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N
k141_2943_5	273526.SMDB11_2527	5.35e-92	284.0	COG1609@1|root,COG1609@2|Bacteria,1R3RD@1224|Proteobacteria,1S1EY@1236|Gammaproteobacteria,402SG@613|Serratia	1236|Gammaproteobacteria	K	helix_turn _helix lactose operon repressor	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_4
k141_2039_1	1121267.JHZL01000009_gene491	1.82e-65	214.0	COG0774@1|root,COG0774@2|Bacteria,1MV6T@1224|Proteobacteria,42MVM@68525|delta/epsilon subdivisions,2YMMR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis	lpxC	-	3.5.1.108	ko:K02535	ko00540,ko01100,map00540,map01100	M00060	R04587	RC00166,RC00300	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	LpxC
k141_1614_4	96561.Dole_3246	7.51e-27	99.8	COG0425@1|root,COG0425@2|Bacteria,1NB2V@1224|Proteobacteria,42VMG@68525|delta/epsilon subdivisions,2WR6Y@28221|Deltaproteobacteria,2MKX9@213118|Desulfobacterales	28221|Deltaproteobacteria	O	Belongs to the sulfur carrier protein TusA family	-	-	-	-	-	-	-	-	-	-	-	-	TusA
k141_1614_5	1121405.dsmv_3303	1.93e-218	607.0	COG2391@1|root,COG2391@2|Bacteria,1NCH7@1224|Proteobacteria,42NKG@68525|delta/epsilon subdivisions,2WJFC@28221|Deltaproteobacteria,2MHNY@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Sulphur transport	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
k141_5072_1	1123274.KB899406_gene1185	1.78e-17	76.6	COG3436@1|root,COG3436@2|Bacteria,2J92E@203691|Spirochaetes	203691|Spirochaetes	L	IS66 Orf2 like protein	-	-	-	ko:K07484	-	-	-	-	ko00000	-	-	-	TnpB_IS66
k141_4045_1	1219065.VPR01S_01_00270	9.25e-276	806.0	COG2902@1|root,COG2902@2|Bacteria,1MXNV@1224|Proteobacteria,1RQVZ@1236|Gammaproteobacteria,1XUBT@135623|Vibrionales	135623|Vibrionales	E	NAD-specific glutamate dehydrogenase	gdhB	-	1.4.1.2	ko:K15371	ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100	-	R00243	RC00006,RC02799	ko00000,ko00001,ko01000	-	-	-	Bac_GDH
k141_4045_2	55601.VANGNB10_cI1258	0.0	1305.0	COG0308@1|root,COG0308@2|Bacteria,1MUCI@1224|Proteobacteria,1RMA7@1236|Gammaproteobacteria,1XUSZ@135623|Vibrionales	135623|Vibrionales	E	COG0308 Aminopeptidase N	pepN	-	3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	DUF3458,DUF3458_C,Peptidase_M1
k141_4045_3	675814.VIC_003971	6.43e-65	207.0	2AM7R@1|root,31C2D@2|Bacteria,1QJDQ@1224|Proteobacteria,1THCV@1236|Gammaproteobacteria,1XU2R@135623|Vibrionales	135623|Vibrionales	-	-	VP1605	-	-	-	-	-	-	-	-	-	-	-	-
k141_4045_4	316275.VSAL_I1544	8.97e-06	47.0	COG0793@1|root,COG0793@2|Bacteria,1MU39@1224|Proteobacteria,1RMSR@1236|Gammaproteobacteria,1XT5Z@135623|Vibrionales	135623|Vibrionales	M	protease	prc	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	BAGE,DUF3340,PDZ,Peptidase_S41
k141_2951_2	592027.CLG_B1549	2.34e-134	444.0	COG2247@1|root,COG2247@2|Bacteria,1UYS6@1239|Firmicutes,24ABJ@186801|Clostridia	186801|Clostridia	M	cell wall binding repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_2951_4	1121324.CLIT_4c00070	6.51e-193	593.0	COG5492@1|root,COG5492@2|Bacteria,1VIXQ@1239|Firmicutes,25FMR@186801|Clostridia	186801|Clostridia	N	S-layer homology domain	-	-	-	-	-	-	-	-	-	-	-	-	SLH
k141_2951_5	1121324.CLIT_2c03850	1.25e-51	186.0	COG0825@1|root,COG0825@2|Bacteria,1VFBH@1239|Firmicutes,24RR1@186801|Clostridia	186801|Clostridia	I	PFAM Copper amine	-	-	-	-	-	-	-	-	-	-	-	-	Cu_amine_oxidN1
k141_2951_6	1121324.CLIT_4c00090	3.89e-124	376.0	COG0793@1|root,COG0793@2|Bacteria,1TPBI@1239|Firmicutes,248HZ@186801|Clostridia,25QD4@186804|Peptostreptococcaceae	186801|Clostridia	M	Belongs to the peptidase S41A family	-	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,PG_binding_1,Peptidase_S41
k141_2951_7	1121289.JHVL01000001_gene1877	1.02e-301	833.0	COG0504@1|root,COG0504@2|Bacteria,1TP34@1239|Firmicutes,2482E@186801|Clostridia,36DBK@31979|Clostridiaceae	186801|Clostridia	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS01075	CTP_synth_N,GATase
k141_2951_10	1121324.CLIT_13c00080	4.02e-109	326.0	COG0248@1|root,COG0248@2|Bacteria,1V978@1239|Firmicutes,25CYW@186801|Clostridia,25UN4@186804|Peptostreptococcaceae	186801|Clostridia	FP	Ppx/GppA phosphatase family	-	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	Ppx-GppA
k141_2951_11	273068.TTE2445	9.79e-06	50.8	COG2919@1|root,COG2919@2|Bacteria,1VIN8@1239|Firmicutes,24U23@186801|Clostridia,42HDA@68295|Thermoanaerobacterales	186801|Clostridia	D	PFAM Septum formation initiator	-	-	-	-	-	-	-	-	-	-	-	-	DivIC
k141_2951_12	596329.HMPREF0631_0292	5.81e-25	95.5	COG1188@1|root,COG1188@2|Bacteria,1VEI5@1239|Firmicutes,24QNF@186801|Clostridia,25RR5@186804|Peptostreptococcaceae	186801|Clostridia	J	S4 domain protein	hslR	-	-	-	-	-	-	-	-	-	-	-	S4
k141_2951_14	1121324.CLIT_13c00040	5.09e-176	510.0	COG1694@1|root,COG3956@2|Bacteria,1TPK1@1239|Firmicutes,247XM@186801|Clostridia,25R1D@186804|Peptostreptococcaceae	186801|Clostridia	S	Tetrapyrrole methylase	mazG	-	3.6.1.66	ko:K02428,ko:K02499	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000,ko03036	-	-	-	MazG,TP_methylase
k141_2951_15	445973.CLOBAR_02493	5.23e-114	353.0	COG1982@1|root,COG1982@2|Bacteria,1TNZ9@1239|Firmicutes,247RA@186801|Clostridia,25QV5@186804|Peptostreptococcaceae	186801|Clostridia	E	Orn Lys Arg decarboxylase, major domain protein	-	-	4.1.1.19	ko:K01585	ko00330,ko01100,map00330,map01100	M00133	R00566	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	OKR_DC_1,OKR_DC_1_C
k141_2951_16	1286171.EAL2_c02710	1.27e-63	215.0	COG2206@1|root,COG2206@2|Bacteria,1TQIM@1239|Firmicutes,248S5@186801|Clostridia	186801|Clostridia	T	PFAM metal-dependent phosphohydrolase, HD sub domain	-	-	-	-	-	-	-	-	-	-	-	-	HD,HD_5
k141_2951_17	1121324.CLIT_17c00040	7.29e-176	511.0	COG0260@1|root,COG0260@2|Bacteria,1TPJZ@1239|Firmicutes,248KF@186801|Clostridia,25S2U@186804|Peptostreptococcaceae	186801|Clostridia	E	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides	pepA	-	3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17,Peptidase_M17_N
k141_2951_18	1286171.EAL2_c01060	3.45e-272	762.0	COG0664@1|root,COG1216@1|root,COG0664@2|Bacteria,COG1216@2|Bacteria	2|Bacteria	V	Glycosyl transferase, family 2	-	-	-	ko:K15762	ko00623,ko00920,ko01100,ko01120,ko01220,map00623,map00920,map01100,map01120,map01220	M00538	R02550,R03562,R05666,R09513	RC00269,RC00490,RC02556	ko00000,ko00001,ko00002	-	-	-	GlcNAc,Glyco_tranf_2_3,Glycos_transf_2,cNMP_binding
k141_2951_19	1121324.CLIT_17c00060	2.86e-185	526.0	COG0297@1|root,COG0297@2|Bacteria,1UHWI@1239|Firmicutes,25E5D@186801|Clostridia	186801|Clostridia	G	Glycosyl transferase 4-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
k141_2951_20	1121324.CLIT_17c00070	2.12e-122	367.0	28IKA@1|root,2Z8M2@2|Bacteria,1TTAG@1239|Firmicutes,24CCS@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_2951_21	1292035.H476_0175	2.75e-23	95.5	2C8AN@1|root,32S6B@2|Bacteria,1VCS0@1239|Firmicutes,24JFN@186801|Clostridia,25RPP@186804|Peptostreptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_2951_22	610130.Closa_3879	1.12e-43	174.0	COG0840@1|root,COG3437@1|root,COG0840@2|Bacteria,COG3437@2|Bacteria,1TQ0S@1239|Firmicutes,24800@186801|Clostridia,223RM@1506553|Lachnoclostridium	186801|Clostridia	T	Diguanylate cyclase and metal dependent phosphohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,HD,HD_5,PAS,PAS_3,PAS_4,PAS_9
k141_2951_23	398512.JQKC01000018_gene2944	3.51e-69	242.0	COG0840@1|root,COG4564@1|root,COG0840@2|Bacteria,COG4564@2|Bacteria,1TP5A@1239|Firmicutes,247S3@186801|Clostridia,3WN4Q@541000|Ruminococcaceae	186801|Clostridia	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal,dCache_1,sCache_2
k141_955_1	675812.VHA_002630	2.96e-33	133.0	2AVXK@1|root,31MRN@2|Bacteria,1QJID@1224|Proteobacteria,1THIM@1236|Gammaproteobacteria,1XW51@135623|Vibrionales	135623|Vibrionales	S	N-acyl homoserine lactone synthase activity	luxM	-	2.3.1.184	ko:K13062	ko00270,ko01100,ko02024,map00270,map01100,map02024	-	R08940	RC00021,RC00039	ko00000,ko00001,ko01000	-	-	-	AHL_synthase
k141_955_2	223926.28806960	1.52e-80	274.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1R81Y@1224|Proteobacteria,1RYQ2@1236|Gammaproteobacteria,1XUTT@135623|Vibrionales	135623|Vibrionales	T	COG0642 Signal transduction histidine kinase	luxN	-	2.7.13.3	ko:K15850	ko02020,ko02024,map02020,map02024	-	-	-	ko00000,ko00001,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,Response_reg
k141_1615_3	1187848.AJYQ01000140_gene1847	6.41e-184	520.0	COG0404@1|root,COG0404@2|Bacteria,1MV96@1224|Proteobacteria,1RN2A@1236|Gammaproteobacteria,1XSK0@135623|Vibrionales	135623|Vibrionales	H	COG0404 Glycine cleavage system T protein (aminomethyltransferase)	gcvT	-	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
k141_4046_1	177437.HRM2_25160	1.26e-106	328.0	COG0529@1|root,COG2046@1|root,COG0529@2|Bacteria,COG2046@2|Bacteria,1MUQB@1224|Proteobacteria,43BR1@68525|delta/epsilon subdivisions,2WIIS@28221|Deltaproteobacteria,2MIQ9@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Catalyzes the synthesis of activated sulfate	cysC	-	2.7.7.4	ko:K00958	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R04929	RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase,ATP-sulfurylase,PUA_2
k141_956_1	1121396.KB893112_gene1983	2.85e-104	321.0	COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,42MH9@68525|delta/epsilon subdivisions,2WJE0@28221|Deltaproteobacteria,2MIF7@213118|Desulfobacterales	28221|Deltaproteobacteria	U	General secretion pathway protein F	gspF	-	-	ko:K02455,ko:K02653	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSF
k141_4050_1	1353529.M899_3452	3.11e-19	90.5	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2MSN1@213481|Bdellovibrionales,2WIT0@28221|Deltaproteobacteria	213481|Bdellovibrionales	T	two component, sigma54 specific, transcriptional regulator, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
k141_4050_2	933262.AXAM01000004_gene2395	4.15e-35	129.0	COG0517@1|root,COG0517@2|Bacteria,1RKZ2@1224|Proteobacteria,42SYQ@68525|delta/epsilon subdivisions,2WP9E@28221|Deltaproteobacteria,2MK65@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
k141_1619_1	431943.CKL_2204	1.17e-112	347.0	COG1351@1|root,COG1351@2|Bacteria,1TRAA@1239|Firmicutes,249DJ@186801|Clostridia,36G0P@31979|Clostridiaceae	186801|Clostridia	H	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant	thyX	-	2.1.1.148	ko:K03465	ko00240,ko00670,ko01100,map00240,map00670,map01100	-	R06613	RC00022,RC00332	ko00000,ko00001,ko01000	-	-	-	Thy1
k141_1619_2	1304885.AUEY01000008_gene2113	7.09e-125	364.0	COG0040@1|root,COG0040@2|Bacteria,1MUCY@1224|Proteobacteria,42N9N@68525|delta/epsilon subdivisions,2WIY9@28221|Deltaproteobacteria,2MHVV@213118|Desulfobacterales	28221|Deltaproteobacteria	E	ATP phosphoribosyltransferase	hisG	-	2.4.2.17	ko:K00765	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002,ko01000	-	-	-	HisG,HisG_C
k141_1619_3	446470.Snas_2600	2.7e-31	112.0	COG0140@1|root,COG0140@2|Bacteria,2IQ4D@201174|Actinobacteria,4EYV0@85014|Glycomycetales	201174|Actinobacteria	E	Phosphoribosyl-ATP pyrophosphohydrolase	hisE	GO:0000287,GO:0003674,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0009605,GO:0009607,GO:0030312,GO:0040007,GO:0043167,GO:0043169,GO:0043207,GO:0044403,GO:0044419,GO:0044464,GO:0046872,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0071944,GO:0075136,GO:0075139	3.6.1.31	ko:K01523	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	PRA-PH
k141_5130_53	398579.Spea_0896	3.24e-37	135.0	COG2078@1|root,COG2078@2|Bacteria,1RJP4@1224|Proteobacteria,1SBD9@1236|Gammaproteobacteria,2QC29@267890|Shewanellaceae	1236|Gammaproteobacteria	S	PFAM AMMECR1 domain protein	-	-	-	ko:K09141	-	-	-	-	ko00000	-	-	-	AMMECR1
k141_5130_54	1565129.JSFF01000021_gene676	9.52e-61	200.0	COG1355@1|root,COG1355@2|Bacteria,1MXK5@1224|Proteobacteria,1RQPK@1236|Gammaproteobacteria,2QARX@267890|Shewanellaceae	1236|Gammaproteobacteria	S	Belongs to the MEMO1 family	-	-	-	ko:K06990	-	-	-	-	ko00000,ko04812	-	-	-	AMMECR1,Memo
k141_5130_55	754436.JCM19237_4400	1.14e-153	443.0	COG1180@1|root,COG1180@2|Bacteria,1R8XY@1224|Proteobacteria,1TH9J@1236|Gammaproteobacteria,1XSRS@135623|Vibrionales	135623|Vibrionales	H	radical SAM	-	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Radical_SAM
k141_5130_58	672.VV93_v1c42890	2.05e-244	675.0	COG0823@1|root,COG0823@2|Bacteria,1MUK9@1224|Proteobacteria,1RNR8@1236|Gammaproteobacteria,1XUFH@135623|Vibrionales	135623|Vibrionales	U	Oligogalacturonate lyase	-	-	4.2.2.6	ko:K01730	ko00040,map00040	-	R04382	RC02124,RC02427	ko00000,ko00001,ko01000	-	-	-	Pectate_lyase22
k141_5130_59	675813.VIB_002457	0.0	897.0	COG0591@1|root,COG0591@2|Bacteria,1MW6E@1224|Proteobacteria,1RXYK@1236|Gammaproteobacteria,1XSDY@135623|Vibrionales	135623|Vibrionales	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	-	-	-	-	-	-	-	-	-	SSF
k141_5130_60	675813.VIB_002456	2.9e-145	431.0	COG0534@1|root,COG0534@2|Bacteria,1MVRV@1224|Proteobacteria,1RNQ7@1236|Gammaproteobacteria,1XUCZ@135623|Vibrionales	135623|Vibrionales	V	Na driven multidrug efflux pump	-	-	-	-	-	-	-	-	-	-	-	-	MatE
k141_5130_61	675813.VIB_002448	0.0	892.0	COG5263@1|root,COG5263@2|Bacteria,1R42H@1224|Proteobacteria,1RY1A@1236|Gammaproteobacteria,1XUDH@135623|Vibrionales	135623|Vibrionales	M	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_5130_62	675813.VIB_002446	0.0	971.0	COG2755@1|root,COG4677@1|root,COG2755@2|Bacteria,COG4677@2|Bacteria,1PGME@1224|Proteobacteria,1RXDT@1236|Gammaproteobacteria,1XVDK@135623|Vibrionales	135623|Vibrionales	G	Pectinesterase	-	-	-	-	-	-	-	-	-	-	-	-	Pectinesterase
k141_5130_63	1348635.BBJY01000005_gene3338	5.49e-125	358.0	COG0698@1|root,COG0698@2|Bacteria,1MWIB@1224|Proteobacteria,1RPEG@1236|Gammaproteobacteria,1XSE3@135623|Vibrionales	135623|Vibrionales	G	Ribose-5-phosphate isomerase	-	-	-	-	-	-	-	-	-	-	-	-	DUF3666,LacAB_rpiB
k141_5130_64	221988.MS0567	1.78e-61	189.0	COG1917@1|root,COG1917@2|Bacteria,1RHSW@1224|Proteobacteria,1S6GC@1236|Gammaproteobacteria,1YA7Q@135625|Pasteurellales	135625|Pasteurellales	S	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
k141_5130_65	675813.VIB_002437	1.06e-158	447.0	COG1028@1|root,COG1028@2|Bacteria,1MWB6@1224|Proteobacteria,1RMZB@1236|Gammaproteobacteria,1XSTX@135623|Vibrionales	135623|Vibrionales	IQ	Enoyl-(Acyl carrier protein) reductase	kduD	-	1.1.1.127	ko:K00065	ko00040,map00040	-	R01542	RC00089	ko00000,ko00001,ko01000	-	-	-	adh_short_C2
k141_2416_2	1511.CLOST_0484	2.44e-117	344.0	COG1624@1|root,COG1624@2|Bacteria,1TPRW@1239|Firmicutes,249K8@186801|Clostridia,25R20@186804|Peptostreptococcaceae	186801|Clostridia	S	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria	dacA	-	2.7.7.85	ko:K18672	-	-	-	-	ko00000,ko01000	-	-	-	DisA_N
k141_2416_3	1131462.DCF50_p1775	1.71e-06	58.5	COG4856@1|root,COG4856@2|Bacteria,1TSIV@1239|Firmicutes,24GKC@186801|Clostridia,2612S@186807|Peptococcaceae	186801|Clostridia	S	PFAM YbbR-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YbbR
k141_2416_4	1408823.AXUS01000007_gene3057	1.44e-147	423.0	COG0280@1|root,COG0280@2|Bacteria,1TRQU@1239|Firmicutes,24857@186801|Clostridia,25RBP@186804|Peptostreptococcaceae	186801|Clostridia	C	phosphate butyryltransferase	ptb	-	2.3.1.19	ko:K00634	ko00650,ko01100,map00650,map01100	-	R01174	RC00004,RC02816	ko00000,ko00001,ko01000	-	-	-	PTA_PTB
k141_2416_5	1476973.JMMB01000007_gene378	2.7e-182	516.0	COG3426@1|root,COG3426@2|Bacteria,1TPKE@1239|Firmicutes,24993@186801|Clostridia,25QTD@186804|Peptostreptococcaceae	186801|Clostridia	H	Belongs to the acetokinase family	buk	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0044237,GO:0044424,GO:0044464,GO:0047761	2.7.2.7	ko:K00929	ko00650,ko01100,map00650,map01100	-	R01688	RC00002,RC00043	ko00000,ko00001,ko01000	-	-	-	Acetate_kinase
k141_2416_6	272563.CD630_01140	7.34e-92	276.0	COG0455@1|root,COG0455@2|Bacteria,1V1FH@1239|Firmicutes,24DP7@186801|Clostridia,25R35@186804|Peptostreptococcaceae	186801|Clostridia	D	bacterial-type flagellum organization	-	-	-	-	-	-	-	-	-	-	-	-	CbiA
k141_2416_7	1408422.JHYF01000003_gene659	2.26e-17	75.9	COG1143@1|root,COG1143@2|Bacteria,1UHZA@1239|Firmicutes,24QVY@186801|Clostridia,36UN5@31979|Clostridiaceae	186801|Clostridia	C	PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein	-	-	1.2.7.3	ko:K00176	ko00020,ko00720,ko01100,ko01120,ko01200,map00020,map00720,map01100,map01120,map01200	M00009,M00011,M00173,M00620	R01197	RC00004,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_4,Fer4_7
k141_2416_8	1286171.EAL2_c18390	4.13e-208	580.0	COG0674@1|root,COG0674@2|Bacteria,1TSSC@1239|Firmicutes,248I6@186801|Clostridia,25VGA@186806|Eubacteriaceae	186801|Clostridia	C	Pyruvate:ferredoxin oxidoreductase core domain II	vorB	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR_N
k141_2416_9	1121324.CLIT_18c00250	6.69e-161	452.0	COG1013@1|root,COG1013@2|Bacteria,1UZ67@1239|Firmicutes,247Q7@186801|Clostridia,25QMV@186804|Peptostreptococcaceae	186801|Clostridia	C	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain protein	-	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
k141_2416_10	1511.CLOST_0493	1.41e-97	287.0	COG1014@1|root,COG1014@2|Bacteria,1UYYG@1239|Firmicutes,24I53@186801|Clostridia,25RBE@186804|Peptostreptococcaceae	186801|Clostridia	C	2-oxoacid acceptor oxidoreductase, gamma subunit, pyruvate 2-ketoisovalerate family	-	-	1.2.7.3	ko:K00177	ko00020,ko00720,ko01100,ko01120,ko01200,map00020,map00720,map01100,map01120,map01200	M00009,M00011,M00173,M00620	R01197	RC00004,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	POR,Rubrerythrin
k141_2416_12	634956.Geoth_3751	5.68e-82	282.0	COG5001@1|root,COG5001@2|Bacteria,1TP8V@1239|Firmicutes,4HA3G@91061|Bacilli,1WE8N@129337|Geobacillus	91061|Bacilli	T	Diguanylate cyclase phosphodiesterase	gmr	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,MASE3,PAS,PAS_8,PAS_9
k141_2416_13	1301100.HG529419_gene3063	3.73e-209	591.0	COG1109@1|root,COG1109@2|Bacteria,1TP1X@1239|Firmicutes,2499P@186801|Clostridia,36DMU@31979|Clostridiaceae	186801|Clostridia	G	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate	glmM	-	5.4.2.10	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	-	R02060	RC00408	ko00000,ko00001,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
k141_2416_14	1410653.JHVC01000002_gene4430	5.36e-179	518.0	COG3829@1|root,COG3829@2|Bacteria,1TP0E@1239|Firmicutes,247MB@186801|Clostridia,36DY7@31979|Clostridiaceae	186801|Clostridia	KT	PFAM sigma-54 factor interaction domain-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,PAS,PAS_9,Sigma54_activat
k141_2416_15	1410653.JHVC01000002_gene4435	8.26e-234	654.0	COG0659@1|root,COG0659@2|Bacteria,1TT9Y@1239|Firmicutes,249RX@186801|Clostridia,36FVG@31979|Clostridiaceae	186801|Clostridia	P	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	Xan_ur_permease
k141_2416_16	1347392.CCEZ01000013_gene2567	1e-296	816.0	COG2368@1|root,COG2368@2|Bacteria,1TQ70@1239|Firmicutes,248RP@186801|Clostridia,36DTV@31979|Clostridiaceae	186801|Clostridia	Q	4-hydroxyphenylacetate 3-hydroxylase C terminal	abfD	-	1.14.14.9,4.2.1.120,5.3.3.3	ko:K00483,ko:K14534	ko00350,ko00650,ko00720,ko01100,ko01120,ko01200,ko01220,map00350,map00650,map00720,map01100,map01120,map01200,map01220	M00374,M00375	R02698,R03031,R03299,R10782	RC00046,RC01857,RC03277	ko00000,ko00001,ko00002,ko01000	-	-	-	HpaB,HpaB_N
k141_2416_17	742733.HMPREF9469_02204	2.72e-13	67.4	COG0694@1|root,COG0694@2|Bacteria,1TV5P@1239|Firmicutes,259JC@186801|Clostridia,221D1@1506553|Lachnoclostridium	186801|Clostridia	O	NifU-like domain	-	-	-	-	-	-	-	-	-	-	-	-	NifU
k141_2416_18	1121289.JHVL01000013_gene1635	2.71e-219	615.0	COG0427@1|root,COG0427@2|Bacteria,1TPHC@1239|Firmicutes,247V0@186801|Clostridia,36FHR@31979|Clostridiaceae	186801|Clostridia	C	acetyl-CoA hydrolase	cat	-	-	ko:K18122	ko00650,ko01100,ko01200,map00650,map01100,map01200	-	R05336	RC00012,RC00014	ko00000,ko00001,ko01000	-	-	-	AcetylCoA_hyd_C,AcetylCoA_hydro
k141_2416_19	431947.PGN_0724	6.04e-168	480.0	COG1454@1|root,COG1454@2|Bacteria,4NE5Y@976|Bacteroidetes,2G351@200643|Bacteroidia,22X4K@171551|Porphyromonadaceae	976|Bacteroidetes	C	4-hydroxybutyrate dehydrogenase	-	-	1.1.1.61	ko:K18120,ko:K19954	ko00650,ko01100,ko01200,map00650,map01100,map01200	-	R01644	RC00087	ko00000,ko00001,ko01000	-	-	-	Fe-ADH
k141_2416_20	1515615.HQ41_00035	1.78e-195	556.0	COG1012@1|root,COG1012@2|Bacteria,4NEAW@976|Bacteroidetes,2FNX5@200643|Bacteroidia,22X3G@171551|Porphyromonadaceae	976|Bacteroidetes	C	Succinate-semialdehyde dehydrogenase	sucD	-	1.2.1.76	ko:K18119	ko00650,ko01100,ko01200,map00650,map01100,map01200	-	R09280	RC00004,RC00184	ko00000,ko00001,ko01000	-	-	-	Aldedh,Fe-ADH
k141_2416_21	444158.MmarC6_0863	1.16e-56	188.0	arCOG03165@1|root,arCOG03165@2157|Archaea,2XXAZ@28890|Euryarchaeota,23QZB@183939|Methanococci	183939|Methanococci	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_2416_22	1121324.CLIT_18c00290	0.0	927.0	COG0449@1|root,COG0449@2|Bacteria,1TPGU@1239|Firmicutes,248F8@186801|Clostridia,25QFM@186804|Peptostreptococcaceae	186801|Clostridia	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	GATase_6,SIS
k141_4812_1	493475.GARC_2323	3.67e-76	231.0	COG3045@1|root,COG3045@2|Bacteria,1RDMP@1224|Proteobacteria,1S29X@1236|Gammaproteobacteria,46D0A@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	CreA protein	creA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K05805	-	-	-	-	ko00000	-	-	-	CreA
k141_458_2	1232437.KL661965_gene3223	8.33e-108	323.0	COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,42NCR@68525|delta/epsilon subdivisions,2WKMY@28221|Deltaproteobacteria,2MHTZ@213118|Desulfobacterales	28221|Deltaproteobacteria	V	ABC transporter transmembrane region	-	-	-	ko:K06147,ko:K18889	ko02010,map02010	M00707	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.106,3.A.1.106.13,3.A.1.106.5,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
k141_1433_1	96561.Dole_2625	3.28e-49	161.0	COG0105@1|root,COG0105@2|Bacteria,1R9ZA@1224|Proteobacteria,42RIR@68525|delta/epsilon subdivisions,2WP3R@28221|Deltaproteobacteria,2MJG6@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate	ndk	GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564	2.7.4.6	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	M00049,M00050,M00052,M00053	R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895	RC00002	ko00000,ko00001,ko00002,ko01000,ko04131	-	-	-	NDK
k141_1433_2	933262.AXAM01000004_gene2366	2.25e-82	254.0	COG0565@1|root,COG0565@2|Bacteria,1N47Y@1224|Proteobacteria,42R3K@68525|delta/epsilon subdivisions,2WJNA@28221|Deltaproteobacteria,2MJFV@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA	trmJ	-	2.1.1.200	ko:K02533,ko:K15396	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
k141_1433_3	177437.HRM2_30270	8.91e-123	371.0	COG4262@1|root,COG4262@2|Bacteria,1QTYC@1224|Proteobacteria,42N8N@68525|delta/epsilon subdivisions,2WKR3@28221|Deltaproteobacteria,2MIDS@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	speE	-	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	Spermine_synth
k141_2099_2	223926.28807240	2.38e-98	295.0	COG1317@1|root,COG1317@2|Bacteria,1RB8Y@1224|Proteobacteria,1T18Q@1236|Gammaproteobacteria,1XTTU@135623|Vibrionales	135623|Vibrionales	N	COG1317 Flagellar biosynthesis type III secretory pathway protein	fliH	-	-	ko:K02411	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	FliH,Yae1_N
k141_2099_3	675815.VOA_002472	1.34e-207	579.0	COG1536@1|root,COG1536@2|Bacteria,1MV9X@1224|Proteobacteria,1RM9B@1236|Gammaproteobacteria,1XSQJ@135623|Vibrionales	135623|Vibrionales	N	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation	fliG	GO:0005575,GO:0005623,GO:0009288,GO:0042995,GO:0043226,GO:0043228,GO:0044464	-	ko:K02410	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliG_C,FliG_M,FliG_N
k141_2099_4	243277.VC_2133	0.0	888.0	COG1766@1|root,COG1766@2|Bacteria,1MUQR@1224|Proteobacteria,1RN6T@1236|Gammaproteobacteria,1XTYM@135623|Vibrionales	135623|Vibrionales	N	The M ring may be actively involved in energy transduction	fliF	-	-	ko:K02409	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	YscJ_FliF,YscJ_FliF_C
k141_2099_5	243277.VC_2134	9.63e-54	170.0	COG1677@1|root,COG1677@2|Bacteria,1N6RZ@1224|Proteobacteria,1SD52@1236|Gammaproteobacteria,1XXSM@135623|Vibrionales	135623|Vibrionales	N	Flagellar hook-basal body	fliE	-	-	ko:K02408	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliE
k141_2099_6	1187848.AJYQ01000115_gene749	9.98e-292	802.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria,1XU64@135623|Vibrionales	135623|Vibrionales	T	COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains	flrC	-	-	ko:K10943	ko02020,ko05111,map02020,map05111	M00515	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
k141_2099_7	1187848.AJYQ01000115_gene750	8.64e-46	157.0	COG5000@1|root,COG5000@2|Bacteria,1QUG9@1224|Proteobacteria,1T1Y1@1236|Gammaproteobacteria,1XSAF@135623|Vibrionales	135623|Vibrionales	T	COG0642 Signal transduction histidine kinase	flrB	-	2.7.13.3	ko:K10942	ko02020,ko05111,map02020,map05111	M00515	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,PAS_8
k141_5131_1	1141662.OOA_02772	2.06e-87	305.0	COG2373@1|root,COG2373@2|Bacteria,1MV7J@1224|Proteobacteria,1RNRY@1236|Gammaproteobacteria,3Z70E@586|Providencia	1236|Gammaproteobacteria	S	COG2373 Large extracellular alpha-helical protein	yfhM	GO:0003674,GO:0004857,GO:0004866,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0009892,GO:0009897,GO:0009986,GO:0010466,GO:0010605,GO:0010951,GO:0016020,GO:0019222,GO:0030162,GO:0030234,GO:0030414,GO:0031224,GO:0031225,GO:0031226,GO:0031233,GO:0031323,GO:0031324,GO:0031362,GO:0032268,GO:0032269,GO:0043086,GO:0044092,GO:0044425,GO:0044459,GO:0044464,GO:0045861,GO:0046658,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0051336,GO:0051346,GO:0052547,GO:0052548,GO:0060255,GO:0061134,GO:0061135,GO:0065007,GO:0065009,GO:0071944,GO:0080090,GO:0098552,GO:0098772	-	ko:K06894	-	-	-	-	ko00000	-	-	-	A2M,A2M_N,A2M_N_2,A2M_comp,MG1,Thiol-ester_cl
k141_749_3	870967.VIS19158_07742	0.0	1014.0	COG0449@1|root,COG0449@2|Bacteria,1MW4K@1224|Proteobacteria,1RMVN@1236|Gammaproteobacteria,1XSTB@135623|Vibrionales	135623|Vibrionales	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	GATase_6,SIS
k141_749_4	675813.VIB_002055	4.05e-132	380.0	COG1349@1|root,COG1349@2|Bacteria,1MUJG@1224|Proteobacteria,1RNW4@1236|Gammaproteobacteria,1XT3D@135623|Vibrionales	135623|Vibrionales	K	COG1349 Transcriptional regulators of sugar metabolism	srlR	-	-	-	-	-	-	-	-	-	-	-	DeoRC,HTH_DeoR
k141_749_5	29495.EA26_02740	1.03e-281	776.0	COG0469@1|root,COG0469@2|Bacteria,1MU21@1224|Proteobacteria,1RMW3@1236|Gammaproteobacteria,1XU2Y@135623|Vibrionales	135623|Vibrionales	G	Belongs to the pyruvate kinase family	pykF	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PK,PK_C
k141_749_6	55601.VANGNB10_cI0354	6e-79	243.0	COG2968@1|root,COG2968@2|Bacteria,1RH7T@1224|Proteobacteria,1RP7T@1236|Gammaproteobacteria,1XUSG@135623|Vibrionales	135623|Vibrionales	S	Protein of unknown function (DUF541)	-	-	-	ko:K09807	-	-	-	-	ko00000	-	-	-	SIMPL
k141_749_7	1219065.VPR01S_21_00420	5.09e-284	779.0	COG0148@1|root,COG0148@2|Bacteria,1MU1N@1224|Proteobacteria,1RNQA@1236|Gammaproteobacteria,1XSWV@135623|Vibrionales	135623|Vibrionales	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	GO:0003674,GO:0003824,GO:0004634,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
k141_749_8	1348635.BBJY01000008_gene1851	0.0	1014.0	COG0504@1|root,COG0504@2|Bacteria,1MUIT@1224|Proteobacteria,1RM92@1236|Gammaproteobacteria,1XSS5@135623|Vibrionales	135623|Vibrionales	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	GO:0003674,GO:0003824,GO:0003883,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_synth_N,GATase
k141_749_9	345073.VC395_2565	3.75e-120	351.0	COG1694@1|root,COG3956@2|Bacteria,1MVKM@1224|Proteobacteria,1RNVU@1236|Gammaproteobacteria,1XVCP@135623|Vibrionales	135623|Vibrionales	S	Nucleoside triphosphate	mazG	-	3.6.1.9	ko:K04765	ko00230,ko00240,ko00760,ko00770,ko01100,map00230,map00240,map00760,map00770,map01100	-	R00086,R00087,R00103,R00287,R00426,R00515,R00662,R00720,R03004,R03036,R11323	RC00002	ko00000,ko00001,ko01000	-	-	-	MazG
k141_749_10	1348635.BBJY01000008_gene1853	0.0	1278.0	COG0317@1|root,COG0317@2|Bacteria,1MU44@1224|Proteobacteria,1RN3H@1236|Gammaproteobacteria,1XTUV@135623|Vibrionales	135623|Vibrionales	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	relA	-	2.7.6.5	ko:K00951	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
k141_749_11	243277.VC_2452	5.69e-198	562.0	COG2265@1|root,COG2265@2|Bacteria,1MV3A@1224|Proteobacteria,1RN1D@1236|Gammaproteobacteria,1XUN9@135623|Vibrionales	135623|Vibrionales	J	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA	rlmD	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TRAM,tRNA_U5-meth_tr
k141_749_12	55601.VANGNB10_cI2216	0.0	1256.0	COG0642@1|root,COG0745@1|root,COG2198@1|root,COG0745@2|Bacteria,COG2198@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,1SKTW@1236|Gammaproteobacteria,1XV4F@135623|Vibrionales	135623|Vibrionales	T	Histidine kinase	barA	-	2.7.13.3	ko:K07678	ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111	M00475	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF2222,HATPase_c,HisKA,Hpt,Response_reg
k141_749_13	55601.VANGNB10_cI2217c	5.62e-51	164.0	COG0736@1|root,COG0736@2|Bacteria,1MZBF@1224|Proteobacteria,1S98P@1236|Gammaproteobacteria,1XXAM@135623|Vibrionales	135623|Vibrionales	I	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein	acpS	GO:0003674,GO:0003824,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008897,GO:0009058,GO:0016740,GO:0016772,GO:0016780,GO:0044238,GO:0071704,GO:1901576	2.7.8.7	ko:K00997	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	-	ACPS
k141_749_14	1517681.HW45_19785	2.28e-146	415.0	COG0854@1|root,COG0854@2|Bacteria,1MU9W@1224|Proteobacteria,1RMS5@1236|Gammaproteobacteria,1XTR0@135623|Vibrionales	135623|Vibrionales	H	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate	pdxJ	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	2.6.99.2	ko:K03474	ko00750,ko01100,map00750,map01100	M00124	R05838	RC01476	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxJ
k141_749_15	29495.EA26_18555	2.57e-132	380.0	COG1381@1|root,COG1381@2|Bacteria,1RHIC@1224|Proteobacteria,1RN8Y@1236|Gammaproteobacteria,1XU1R@135623|Vibrionales	135623|Vibrionales	L	Involved in DNA repair and RecF pathway recombination	recO	-	-	ko:K03584	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecO_C,RecO_N
k141_749_16	1348635.BBJY01000008_gene1859	4.83e-211	585.0	COG1159@1|root,COG1159@2|Bacteria,1MUKT@1224|Proteobacteria,1RN3A@1236|Gammaproteobacteria,1XUB4@135623|Vibrionales	135623|Vibrionales	S	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism	era	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0005488,GO:0005525,GO:0017076,GO:0019001,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	ko:K03595	-	-	-	-	ko00000,ko03009,ko03029	-	-	-	KH_2,MMR_HSR1
k141_749_17	1280001.BAOA01000068_gene2685	5.03e-134	382.0	COG0571@1|root,COG0571@2|Bacteria,1MUQ6@1224|Proteobacteria,1RN0C@1236|Gammaproteobacteria,1XTPC@135623|Vibrionales	135623|Vibrionales	J	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism	rnc	GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	-	-	-	Ribonucleas_3_3,dsrm
k141_749_18	575788.VS_2620	1.67e-152	435.0	COG0681@1|root,COG0681@2|Bacteria,1MXUF@1224|Proteobacteria,1RMHI@1236|Gammaproteobacteria,1XUWQ@135623|Vibrionales	135623|Vibrionales	U	Belongs to the peptidase S26 family	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
k141_749_19	29495.EA26_18575	0.0	1110.0	COG0481@1|root,COG0481@2|Bacteria,1MVZA@1224|Proteobacteria,1RPFB@1236|Gammaproteobacteria,1XTJC@135623|Vibrionales	135623|Vibrionales	M	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0005488,GO:0005525,GO:0017076,GO:0019001,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C
k141_749_20	1517681.HW45_19755	4.6e-51	167.0	COG3086@1|root,COG3086@2|Bacteria,1N6QS@1224|Proteobacteria,1SCTM@1236|Gammaproteobacteria,1XWZF@135623|Vibrionales	135623|Vibrionales	T	COG3086 Positive regulator of sigma E activity	rseC	-	-	ko:K03803	-	-	-	-	ko00000,ko03021	-	-	-	RseC_MucC
k141_749_21	675813.VIB_000366	1.67e-164	468.0	COG3026@1|root,COG3026@2|Bacteria,1MUQ8@1224|Proteobacteria,1RNF3@1236|Gammaproteobacteria,1XSY1@135623|Vibrionales	135623|Vibrionales	T	COG3026 Negative regulator of sigma E activity	rseB	-	-	ko:K03598	-	-	-	-	ko00000,ko03021	-	-	-	MucB_RseB,MucB_RseB_C
k141_749_22	675813.VIB_000367	2.6e-71	222.0	COG3073@1|root,COG3073@2|Bacteria,1R4U0@1224|Proteobacteria,1RN98@1236|Gammaproteobacteria,1XSUI@135623|Vibrionales	135623|Vibrionales	T	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E	rseA	-	-	ko:K03597	-	-	-	-	ko00000,ko03021	-	-	-	RseA_C,RseA_N
k141_749_23	55601.VANGNB10_cI2227c	7.54e-121	346.0	COG1595@1|root,COG1595@2|Bacteria,1MX7T@1224|Proteobacteria,1RN64@1236|Gammaproteobacteria,1XT4Z@135623|Vibrionales	135623|Vibrionales	K	Belongs to the sigma-70 factor family. ECF subfamily	rpoE	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
k141_749_24	243277.VC_2469	0.0	901.0	COG0029@1|root,COG0029@2|Bacteria,1RBQW@1224|Proteobacteria,1RMMD@1236|Gammaproteobacteria,1XT0I@135623|Vibrionales	135623|Vibrionales	H	Catalyzes the oxidation of L-aspartate to iminoaspartate	nadB	GO:0001716,GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008734,GO:0009117,GO:0009987,GO:0015922,GO:0016491,GO:0016638,GO:0016641,GO:0019362,GO:0019637,GO:0019674,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0055086,GO:0055114,GO:0071704,GO:0072524,GO:1901360,GO:1901564	1.4.3.16	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	M00115	R00357,R00481	RC00006,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
k141_749_25	675815.VOA_002781	0.000186	45.4	2AWTA@1|root,31NQC@2|Bacteria,1QKET@1224|Proteobacteria,1TIIR@1236|Gammaproteobacteria,1XZ7D@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_749_26	55601.VANGNB10_cI2230c	1.79e-40	135.0	COG2938@1|root,COG2938@2|Bacteria,1N7P4@1224|Proteobacteria,1SCKB@1236|Gammaproteobacteria,1XXUM@135623|Vibrionales	135623|Vibrionales	S	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH and other flavinylated proteins as well	sdhE	GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016999,GO:0017144,GO:0018065,GO:0018293,GO:0019538,GO:0019752,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350,GO:1901564	-	ko:K09159	-	-	-	-	ko00000,ko02048	-	-	-	Sdh5
k141_749_27	1051646.VITU9109_03660	7.28e-133	387.0	COG0354@1|root,COG0354@2|Bacteria,1N852@1224|Proteobacteria,1RPWB@1236|Gammaproteobacteria,1XTWH@135623|Vibrionales	135623|Vibrionales	J	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication	ygfZ	GO:0006790,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0044085,GO:0044237,GO:0051186,GO:0071840	-	ko:K06980	-	-	-	-	ko00000,ko03016	-	-	-	GCV_T
k141_749_28	870967.VIS19158_07882	3.1e-56	180.0	COG2606@1|root,COG2606@2|Bacteria,1QJRS@1224|Proteobacteria,1SHYA@1236|Gammaproteobacteria,1XXFV@135623|Vibrionales	135623|Vibrionales	S	Aminoacyl-tRNA editing domain	-	-	-	ko:K19055	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA_edit
k141_749_29	1136163.M565_ctg1P0041	3.76e-32	112.0	2CTIP@1|root,32STK@2|Bacteria,1MZ8V@1224|Proteobacteria,1SEQR@1236|Gammaproteobacteria,1XYB9@135623|Vibrionales	135623|Vibrionales	S	Protein of unknown function (DUF1107)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1107
k141_749_30	55601.VANGNB10_cI2234c	1.01e-190	541.0	COG0654@1|root,COG0654@2|Bacteria,1MU6I@1224|Proteobacteria,1RND5@1236|Gammaproteobacteria,1XU9H@135623|Vibrionales	135623|Vibrionales	CH	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	visC	-	-	ko:K18800	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04987,R08768	RC00046	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_3
k141_749_31	55601.VANGNB10_cI2235c	4.87e-145	424.0	COG0654@1|root,COG0654@2|Bacteria,1MU6I@1224|Proteobacteria,1RMS3@1236|Gammaproteobacteria,1XTCE@135623|Vibrionales	135623|Vibrionales	CH	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	ubiH	-	-	ko:K03185	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04989,R08773	RC02670	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_3
k141_749_32	345073.VC395_2591	1.11e-65	207.0	COG3079@1|root,COG3079@2|Bacteria,1N7W0@1224|Proteobacteria,1SCPW@1236|Gammaproteobacteria,1XT2F@135623|Vibrionales	135623|Vibrionales	S	Belongs to the UPF0149 family	VV2847	-	-	ko:K09895	-	-	-	-	ko00000	-	-	-	UPF0149
k141_749_33	55601.VANGNB10_cI2237	2.23e-37	128.0	COG3027@1|root,COG3027@2|Bacteria,1NJEZ@1224|Proteobacteria,1SAG6@1236|Gammaproteobacteria,1XYD2@135623|Vibrionales	135623|Vibrionales	D	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division	zapA	-	-	ko:K09888	-	-	-	-	ko00000,ko03036	-	-	-	ZapA
k141_749_34	945550.VISI1226_03064	8.91e-89	267.0	COG0212@1|root,COG0212@2|Bacteria,1MZG0@1224|Proteobacteria,1S612@1236|Gammaproteobacteria,1XT1H@135623|Vibrionales	135623|Vibrionales	H	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family	ygfA	-	6.3.3.2	ko:K01934	ko00670,ko01100,map00670,map01100	-	R02301	RC00183	ko00000,ko00001,ko01000	-	-	-	5-FTHF_cyc-lig
k141_749_35	1187848.AJYQ01000032_gene2252	1.04e-123	356.0	COG0120@1|root,COG0120@2|Bacteria,1MVGR@1224|Proteobacteria,1RNF8@1236|Gammaproteobacteria,1XSM7@135623|Vibrionales	135623|Vibrionales	G	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate	rpiA	GO:0003674,GO:0003824,GO:0004751,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006014,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009117,GO:0009987,GO:0016853,GO:0016860,GO:0016861,GO:0019321,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564	5.3.1.6	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167,M00580	R01056	RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	Rib_5-P_isom_A
k141_749_36	223926.28807603	1.04e-235	655.0	COG0111@1|root,COG0111@2|Bacteria,1MU5Z@1224|Proteobacteria,1RPEY@1236|Gammaproteobacteria,1XSKJ@135623|Vibrionales	135623|Vibrionales	C	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family	serA	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C,ACT
k141_749_37	345073.VC395_2596	3.8e-88	261.0	COG0440@1|root,COG0440@2|Bacteria,1RAGN@1224|Proteobacteria,1S20I@1236|Gammaproteobacteria,1XTRE@135623|Vibrionales	135623|Vibrionales	E	COG0440 Acetolactate synthase, small (regulatory) subunit	ilvH	-	2.2.1.6	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,ACT_5,ALS_ss_C
k141_749_38	55601.VANGNB10_cI2242c	0.0	1021.0	COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,1RMQQ@1236|Gammaproteobacteria,1XSYI@135623|Vibrionales	135623|Vibrionales	H	COG0028 Thiamine pyrophosphate-requiring enzymes acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase	ilvI	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
k141_749_39	1280001.BAOA01000021_gene840	1.99e-167	476.0	COG0583@1|root,COG0583@2|Bacteria,1MX24@1224|Proteobacteria,1RQP0@1236|Gammaproteobacteria,1XV0S@135623|Vibrionales	135623|Vibrionales	K	Transcriptional regulator	leuO	-	-	ko:K05798	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,LysR_substrate
k141_749_40	945550.VISI1226_10587	0.0	1274.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,1XTIP@135623|Vibrionales	135623|Vibrionales	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k141_2757_34	592026.GCWU0000282_002627	1.94e-69	217.0	2BY0N@1|root,2ZBND@2|Bacteria,1TS3Y@1239|Firmicutes,24EZ3@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	ko:K16926	-	M00582	-	-	ko00000,ko00002,ko02000	3.A.1.31	-	-	Trep_Strep
k141_2757_35	592026.GCWU0000282_001722	4.81e-169	499.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247PY@186801|Clostridia	186801|Clostridia	V	abc transporter atp-binding protein	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
k141_2757_36	742741.HMPREF9475_02783	1.58e-188	549.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247VZ@186801|Clostridia,21Z8B@1506553|Lachnoclostridium	186801|Clostridia	V	ABC transporter transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
k141_2757_37	1423806.JCM15457_674	2.01e-24	102.0	COG1309@1|root,COG1309@2|Bacteria,1UW9B@1239|Firmicutes,4I3WZ@91061|Bacilli,3F7T3@33958|Lactobacillaceae	91061|Bacilli	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
k141_2757_38	411902.CLOBOL_02199	0.0	1543.0	COG1020@1|root,COG1020@2|Bacteria,1TPTH@1239|Firmicutes,2490U@186801|Clostridia,21Z42@1506553|Lachnoclostridium	186801|Clostridia	Q	Belongs to the ATP-dependent AMP-binding enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,NAD_binding_4,PP-binding
k141_2757_39	1487953.JMKF01000037_gene3244	2.34e-25	119.0	COG0236@1|root,COG0318@1|root,COG1960@1|root,COG0236@2|Bacteria,COG0318@2|Bacteria,COG1960@2|Bacteria,1G4XD@1117|Cyanobacteria	1117|Cyanobacteria	IQ	Acyl-CoA dehydrogenase, middle domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N,PP-binding
k141_2757_40	1123075.AUDP01000030_gene1832	3.37e-25	105.0	COG2091@1|root,COG2091@2|Bacteria,1VEYZ@1239|Firmicutes,24RQ3@186801|Clostridia,3WM4E@541000|Ruminococcaceae	186801|Clostridia	H	4'-phosphopantetheinyl transferase superfamily	sfp	-	-	ko:K06133	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	-	ACPS
k141_2757_41	588581.Cpap_1768	4.25e-90	290.0	COG1020@1|root,COG1020@2|Bacteria,1TPTH@1239|Firmicutes,2490U@186801|Clostridia,3WGCA@541000|Ruminococcaceae	186801|Clostridia	Q	TIGRFAM amino acid adenylation domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Acyl_transf_1,Condensation,KAsynt_C_assoc,Ketoacyl-synt_C,Methyltransf_12,NAD_binding_4,PP-binding,ketoacyl-synt
k141_2757_42	411469.EUBHAL_00448	3.4e-267	810.0	COG1020@1|root,COG1020@2|Bacteria,1TPTH@1239|Firmicutes,2490U@186801|Clostridia,25W28@186806|Eubacteriaceae	186801|Clostridia	Q	Condensation domain	-	-	-	ko:K04784,ko:K12240	ko01053,map01053	-	-	-	ko00000,ko00001,ko01004,ko01008	-	-	-	AMP-binding,AMP-binding_C,Condensation,Methyltransf_12,NAD_binding_4,PP-binding,Thioesterase
k141_2757_43	588581.Cpap_1769	2.49e-125	371.0	COG4693@1|root,COG4693@2|Bacteria,1UY66@1239|Firmicutes,24ICV@186801|Clostridia,3WMUW@541000|Ruminococcaceae	186801|Clostridia	Q	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,Methyltransf_12
k141_236_1	96561.Dole_3272	1.45e-159	479.0	COG0784@1|root,COG2202@1|root,COG3437@1|root,COG3829@1|root,COG4191@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG3437@2|Bacteria,COG3829@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42M1R@68525|delta/epsilon subdivisions,2WK3J@28221|Deltaproteobacteria,2MI5F@213118|Desulfobacterales	28221|Deltaproteobacteria	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg,SBP_bac_3
k141_3217_1	1121405.dsmv_2833	4.18e-75	250.0	COG0249@1|root,COG0249@2|Bacteria,1MUGX@1224|Proteobacteria,42MRR@68525|delta/epsilon subdivisions,2WIQ7@28221|Deltaproteobacteria,2MIGW@213118|Desulfobacterales	28221|Deltaproteobacteria	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	mutS	GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
k141_1225_1	1223523.H340_14896	6.06e-22	97.4	COG0834@1|root,COG0834@2|Bacteria,2GJH8@201174|Actinobacteria	201174|Actinobacteria	ET	Belongs to the bacterial solute-binding protein 3 family	-	-	-	ko:K10005	ko02010,map02010	M00233	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3.9	-	-	SBP_bac_3
k141_237_1	40215.BBOS01000003_gene873	5.03e-56	193.0	COG1123@1|root,COG4172@2|Bacteria,1MU09@1224|Proteobacteria,1RMEI@1236|Gammaproteobacteria,3NIPB@468|Moraxellaceae	1236|Gammaproteobacteria	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K02031,ko:K02032,ko:K10823,ko:K13896,ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00349,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.21,3.A.1.5.24,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
k141_3218_1	1267005.KB911260_gene3473	4.15e-15	74.3	2DBB3@1|root,2Z85F@2|Bacteria,1N6NI@1224|Proteobacteria	1224|Proteobacteria	S	Domain of unknown function (4846)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4846
k141_1227_1	1265505.ATUG01000001_gene4802	4.86e-49	169.0	COG1136@1|root,COG1136@2|Bacteria,1PXKV@1224|Proteobacteria,42PI6@68525|delta/epsilon subdivisions,2WJT8@28221|Deltaproteobacteria,2MIQT@213118|Desulfobacterales	28221|Deltaproteobacteria	V	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
k141_238_1	123899.JPQP01000001_gene1740	4.32e-52	182.0	COG0477@1|root,COG2814@2|Bacteria,1QTY0@1224|Proteobacteria,2WGHA@28216|Betaproteobacteria,3T36K@506|Alcaligenaceae	28216|Betaproteobacteria	U	the major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
k141_4926_2	243277.VC_2624	1.06e-106	313.0	COG0546@1|root,COG0546@2|Bacteria,1RDDY@1224|Proteobacteria,1S3QD@1236|Gammaproteobacteria,1XUKY@135623|Vibrionales	135623|Vibrionales	G	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress	gph	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008967,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
k141_547_1	1101190.ARWB01000001_gene3074	1.93e-47	174.0	COG0392@1|root,COG2898@1|root,COG0392@2|Bacteria,COG2898@2|Bacteria,1MXH9@1224|Proteobacteria,2TUMC@28211|Alphaproteobacteria,36Y3D@31993|Methylocystaceae	28211|Alphaproteobacteria	S	Lysylphosphatidylglycerol synthase TM region	-	-	2.3.2.3	ko:K07027,ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	M00726	-	-	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	2.A.1.3.37,4.D.2	-	-	DUF2156,LPG_synthase_TM
k141_239_1	272562.CA_C2356	6.14e-17	85.1	COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria,1TP98@1239|Firmicutes,248BJ@186801|Clostridia,36DSY@31979|Clostridiaceae	186801|Clostridia	J	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily	pheT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA-synt_2d,tRNA_bind
k141_4927_1	926550.CLDAP_37400	1.02e-24	108.0	COG0577@1|root,COG0577@2|Bacteria,2G6IW@200795|Chloroflexi	200795|Chloroflexi	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
k141_1228_1	879212.DespoDRAFT_01333	1.02e-135	402.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,2MIB8@213118|Desulfobacterales	28221|Deltaproteobacteria	T	response regulator receiver	-	-	-	ko:K02481,ko:K07713	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
k141_3895_1	218491.ECA3174	1.86e-132	387.0	COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,1RM9E@1236|Gammaproteobacteria,1MRVK@122277|Pectobacterium	1236|Gammaproteobacteria	P	Belongs to the ABC transporter superfamily	malK	-	-	ko:K10111,ko:K10191	ko02010,map02010	M00194,M00199,M00200,M00204,M00207,M00491	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.1,3.A.1.1.4	-	-	ABC_tran,TOBE_2
k141_3895_2	1166016.W5S_0869	1.54e-122	362.0	COG1609@1|root,COG1609@2|Bacteria,1N8ZA@1224|Proteobacteria,1RSGV@1236|Gammaproteobacteria,1MRF3@122277|Pectobacterium	1236|Gammaproteobacteria	K	Transcriptional regulator	ebgR	GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141	-	ko:K02529,ko:K12113	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
k141_3895_3	1116375.VEJY3_22251	0.0	1114.0	COG1472@1|root,COG1472@2|Bacteria,1MVIV@1224|Proteobacteria,1RMA0@1236|Gammaproteobacteria,1XVI1@135623|Vibrionales	135623|Vibrionales	G	Fibronectin type III-like domain	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
k141_3895_4	1205908.AKXW01000072_gene3418	2.19e-91	281.0	COG0624@1|root,COG0624@2|Bacteria,1MVUX@1224|Proteobacteria,1RPPD@1236|Gammaproteobacteria,1XV99@135623|Vibrionales	135623|Vibrionales	E	Peptidase family M20/M25/M40	-	-	3.5.3.9	ko:K02083	ko00230,ko01120,map00230,map01120	-	R02423	RC00064	ko00000,ko00001,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
k141_3219_2	1410619.SRDD_29360	4.39e-11	70.1	COG1372@1|root,COG3209@1|root,COG1372@2|Bacteria,COG3209@2|Bacteria,1MVV1@1224|Proteobacteria,1SKYM@1236|Gammaproteobacteria,404A4@613|Serratia	1236|Gammaproteobacteria	M	RHS Repeat	-	-	-	-	-	-	-	-	-	-	-	-	RHS,RHS_repeat
k141_3552_1	223926.28805892	3.11e-60	198.0	COG0168@1|root,COG0168@2|Bacteria,1N412@1224|Proteobacteria,1RR24@1236|Gammaproteobacteria,1XSUX@135623|Vibrionales	135623|Vibrionales	P	COG0168 Trk-type K transport systems, membrane components	ktrB	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
k141_3552_2	1517681.HW45_21970	4.57e-58	183.0	COG0517@1|root,COG0517@2|Bacteria,1N2XI@1224|Proteobacteria,1SA5K@1236|Gammaproteobacteria,1XXA2@135623|Vibrionales	135623|Vibrionales	S	COG0517 FOG CBS domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS
k141_3552_3	1219080.VEZ01S_09_00410	1.46e-129	374.0	COG2820@1|root,COG2820@2|Bacteria,1P0EC@1224|Proteobacteria,1RN3N@1236|Gammaproteobacteria,1XSZE@135623|Vibrionales	135623|Vibrionales	F	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis	udp	-	2.4.2.3	ko:K00757	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01876,R02484,R08229	RC00063	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
k141_3552_4	1348635.BBJY01000011_gene1225	3.19e-118	345.0	2AZSG@1|root,31S1S@2|Bacteria,1QJ9C@1224|Proteobacteria,1TH7Y@1236|Gammaproteobacteria,1XSAD@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_548_1	96561.Dole_2568	1.18e-20	90.5	COG0284@1|root,COG0284@2|Bacteria,1MW2C@1224|Proteobacteria,42N5N@68525|delta/epsilon subdivisions,2WMJ5@28221|Deltaproteobacteria,2MHNM@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)	pyrF	GO:0003674,GO:0003824,GO:0004590,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase
k141_548_2	123214.PERMA_1349	1.71e-59	192.0	COG0500@1|root,COG2226@2|Bacteria,2G4VU@200783|Aquificae	200783|Aquificae	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
k141_2186_1	1219077.VAZ01S_020_00640	5.47e-54	183.0	COG1236@1|root,COG1236@2|Bacteria,1MUDD@1224|Proteobacteria,1RPZC@1236|Gammaproteobacteria,1XUP7@135623|Vibrionales	135623|Vibrionales	J	exonuclease of the beta-lactamase fold involved in RNA processing	-	-	-	ko:K07576	-	-	-	-	ko00000	-	-	-	Beta-Casp,Lactamase_B,RMMBL
k141_2186_2	1187848.AJYQ01000004_gene196	4.22e-223	637.0	COG0471@1|root,COG0490@1|root,COG0471@2|Bacteria,COG0490@2|Bacteria,1MU0K@1224|Proteobacteria,1RMI1@1236|Gammaproteobacteria,1XTKK@135623|Vibrionales	135623|Vibrionales	P	COG0471 Di- and tricarboxylate transporters	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS,TrkA_C
k141_2186_3	1187848.AJYQ01000004_gene197	7.99e-200	555.0	COG0175@1|root,COG0175@2|Bacteria,1MUCZ@1224|Proteobacteria,1RNAD@1236|Gammaproteobacteria,1XTPJ@135623|Vibrionales	135623|Vibrionales	H	Sulfate adenylyltransferase subunit 2	cysD	-	2.7.7.4	ko:K00957	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R04929	RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	PAPS_reduct
k141_2186_4	1187848.AJYQ01000004_gene198	6.65e-115	333.0	COG0529@1|root,COG0529@2|Bacteria,1MX0D@1224|Proteobacteria,1RNWT@1236|Gammaproteobacteria,1XUJT@135623|Vibrionales	135623|Vibrionales	F	Catalyzes the synthesis of activated sulfate	cysC	-	2.7.1.25	ko:K00860	ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120	M00176	R00509,R04928	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase
k141_2186_5	1187848.AJYQ01000004_gene199	4.5e-149	429.0	COG0608@1|root,COG0608@2|Bacteria,1N37P@1224|Proteobacteria,1RQTR@1236|Gammaproteobacteria,1XTYY@135623|Vibrionales	135623|Vibrionales	L	single-stranded DNA 5'-3' exodeoxyribonuclease activity	-	-	-	-	-	-	-	-	-	-	-	-	DHHA1
k141_2186_6	1187848.AJYQ01000004_gene200	7.29e-293	805.0	COG2895@1|root,COG2895@2|Bacteria,1MUD9@1224|Proteobacteria,1RME4@1236|Gammaproteobacteria,1XSCY@135623|Vibrionales	135623|Vibrionales	H	Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily	cysN	-	2.7.7.4	ko:K00956	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R04929	RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_EFTU,GTP_EFTU_D3
k141_2186_7	298386.PBPRA2697	6.99e-91	270.0	COG2148@1|root,COG2148@2|Bacteria,1R4J5@1224|Proteobacteria,1RP9R@1236|Gammaproteobacteria,1XT9C@135623|Vibrionales	135623|Vibrionales	M	COG2148 Sugar transferases involved in lipopolysaccharide synthesis	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf
k141_2186_8	55601.VANGNB10_cI2502c	3.54e-106	319.0	COG0451@1|root,COG0451@2|Bacteria,1MX2J@1224|Proteobacteria,1RPHW@1236|Gammaproteobacteria,1XVMH@135623|Vibrionales	135623|Vibrionales	M	Male sterility protein	galE-1	-	-	-	-	-	-	-	-	-	-	-	Epimerase
k141_2186_9	55601.VANGNB10_cI2503	0.0	976.0	COG1086@1|root,COG1086@2|Bacteria,1MWKY@1224|Proteobacteria,1RNQ2@1236|Gammaproteobacteria,1XUT0@135623|Vibrionales	135623|Vibrionales	GM	nucleoside-diphosphate sugar epimerases	-	-	-	-	-	-	-	-	-	-	-	-	CoA_binding_3,Polysacc_synt_2
k141_1890_1	1121405.dsmv_0622	1.79e-100	300.0	COG0727@1|root,COG0727@2|Bacteria,1Q0JM@1224|Proteobacteria,42N6S@68525|delta/epsilon subdivisions,2WMTR@28221|Deltaproteobacteria,2MIXY@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Putative zinc- or iron-chelating domain	-	-	-	ko:K06940	-	-	-	-	ko00000	-	-	-	CxxCxxCC
k141_1890_2	1121456.ATVA01000012_gene2643	9.26e-45	154.0	COG0727@1|root,COG0727@2|Bacteria,1RG3R@1224|Proteobacteria,42RR7@68525|delta/epsilon subdivisions,2WP18@28221|Deltaproteobacteria,2MBKF@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	PFAM Uncharacterised protein family (UPF0153)	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_1890_3	1304885.AUEY01000003_gene554	2.05e-163	468.0	COG0232@1|root,COG0232@2|Bacteria,1MVQ2@1224|Proteobacteria,42P1T@68525|delta/epsilon subdivisions,2WKZB@28221|Deltaproteobacteria,2MI0P@213118|Desulfobacterales	28221|Deltaproteobacteria	F	TIGRFAM deoxyguanosinetriphosphate triphosphohydrolase	-	-	3.1.5.1	ko:K01129	ko00230,map00230	-	R01856	RC00017	ko00000,ko00001,ko01000	-	-	-	HD,HD_assoc
k141_1890_4	1304885.AUEY01000003_gene553	1.99e-50	167.0	2ARUS@1|root,31H6C@2|Bacteria,1RFAK@1224|Proteobacteria,42SPB@68525|delta/epsilon subdivisions,2WPJK@28221|Deltaproteobacteria,2MKD1@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Type I restriction enzyme R protein N terminus (HSDR_N)	-	-	-	-	-	-	-	-	-	-	-	-	HSDR_N_2
k141_1890_5	177437.HRM2_04570	1.05e-37	134.0	COG0590@1|root,COG0590@2|Bacteria,1RIK5@1224|Proteobacteria,42T2I@68525|delta/epsilon subdivisions,2WPRC@28221|Deltaproteobacteria,2MJWC@213118|Desulfobacterales	28221|Deltaproteobacteria	FJ	PFAM CMP dCMP deaminase zinc-binding	-	-	3.5.4.33	ko:K11991	-	-	R10223	RC00477	ko00000,ko01000,ko03016	-	-	-	dCMP_cyt_deam_1
k141_1890_6	667014.Thein_1593	1.3e-61	196.0	COG0290@1|root,COG0290@2|Bacteria,2GH65@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	J	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins	infC	-	-	ko:K02520	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	IF3_C,IF3_N
k141_1890_7	1042156.CXIVA_23430	5.74e-21	84.3	COG0291@1|root,COG0291@2|Bacteria,1VF5W@1239|Firmicutes,24QJD@186801|Clostridia,36MNG@31979|Clostridiaceae	186801|Clostridia	J	Belongs to the bacterial ribosomal protein bL35 family	rpmI	-	-	ko:K02916	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L35p
k141_1890_8	338963.Pcar_1421	4.43e-46	151.0	COG0292@1|root,COG0292@2|Bacteria,1RGU2@1224|Proteobacteria,42REF@68525|delta/epsilon subdivisions,2WQ4F@28221|Deltaproteobacteria,43UVT@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit	rplT	GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904	-	ko:K02887	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L20
k141_252_2	1397284.AYMN01000140_gene2595	1.08e-07	51.2	2EJJZ@1|root,33DAV@2|Bacteria,1NHZ6@1224|Proteobacteria,1SGIQ@1236|Gammaproteobacteria,4056S@613|Serratia	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_4609_1	1219080.VEZ01S_04_00350	1.03e-141	409.0	COG0463@1|root,COG0463@2|Bacteria,1MXC1@1224|Proteobacteria,1RRHP@1236|Gammaproteobacteria,1XTZ5@135623|Vibrionales	135623|Vibrionales	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
k141_4609_2	575788.VS_2433	4.23e-73	248.0	COG1287@1|root,COG1287@2|Bacteria,1RCIB@1224|Proteobacteria,1THEW@1236|Gammaproteobacteria,1XV44@135623|Vibrionales	135623|Vibrionales	S	oligosaccharyl transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_3901_1	948565.AFFP02000006_gene262	2.15e-52	181.0	COG0128@1|root,COG0128@2|Bacteria,1MWMK@1224|Proteobacteria,1RQ8U@1236|Gammaproteobacteria,1Y6QT@135625|Pasteurellales	135625|Pasteurellales	E	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	aroA	GO:0003674,GO:0003824,GO:0003866,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	EPSP_synthase
k141_2838_1	999423.HMPREF9161_01768	2.93e-12	67.8	COG0513@1|root,COG0513@2|Bacteria,1TPAP@1239|Firmicutes,4H27M@909932|Negativicutes	909932|Negativicutes	L	DEAD DEAH box helicase	deaD	-	3.6.4.13	ko:K05592	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	DEAD,Helicase_C
k141_2838_2	1450525.JATV01000005_gene449	2.85e-18	86.7	COG3124@1|root,COG3124@2|Bacteria,4NHQK@976|Bacteroidetes,1I1CI@117743|Flavobacteriia,2NTMP@237|Flavobacterium	976|Bacteroidetes	S	ACP phosphodiesterase	acpH	-	-	-	-	-	-	-	-	-	-	-	ACP_PD
k141_2838_4	1051646.VITU9109_23534	3.84e-205	584.0	COG0654@1|root,COG0654@2|Bacteria,1NPQT@1224|Proteobacteria,1T1YT@1236|Gammaproteobacteria,1XTXS@135623|Vibrionales	135623|Vibrionales	CH	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
k141_2838_5	1001530.BACE01000027_gene958	3.25e-91	284.0	28HEC@1|root,2Z7QS@2|Bacteria,1N54Y@1224|Proteobacteria,1SA2G@1236|Gammaproteobacteria,1XVIF@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_4222_1	1316927.ATKI01000034_gene4683	2.26e-30	124.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1YT39@136843|Pseudomonas fluorescens group	1236|Gammaproteobacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF,PAS,PAS_3,PAS_4,PAS_9,Response_reg
k141_2839_1	1499967.BAYZ01000173_gene5786	2.84e-44	164.0	COG0574@1|root,COG0574@2|Bacteria,2NQKM@2323|unclassified Bacteria	2|Bacteria	G	Pyruvate phosphate dikinase, PEP/pyruvate binding domain	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transf_2,PPDK_N,Response_reg
k141_5193_3	1423321.AS29_21305	5.14e-14	74.7	COG0262@1|root,COG0262@2|Bacteria,1VAUA@1239|Firmicutes,4HH71@91061|Bacilli,1ZEDJ@1386|Bacillus	91061|Bacilli	H	RibD C-terminal domain	ywjB	-	-	-	-	-	-	-	-	-	-	-	RibD_C
k141_5193_4	1353529.M899_1347	4.17e-79	291.0	COG0642@1|root,COG4251@1|root,COG5002@1|root,COG0642@2|Bacteria,COG2205@2|Bacteria,COG4251@2|Bacteria,COG5002@2|Bacteria,1NRP8@1224|Proteobacteria,42M0Y@68525|delta/epsilon subdivisions,2MTI7@213481|Bdellovibrionales,2WIR4@28221|Deltaproteobacteria	213481|Bdellovibrionales	T	Histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,HATPase_c,HisKA,PAS_3,Response_reg
k141_5193_5	1145276.T479_06240	2.16e-09	62.4	COG0697@1|root,COG0697@2|Bacteria,1V05H@1239|Firmicutes,4HFFB@91061|Bacilli	91061|Bacilli	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
k141_5193_6	83406.HDN1F_09910	5.25e-05	50.4	COG0697@1|root,COG0697@2|Bacteria,1MYHQ@1224|Proteobacteria,1S4AM@1236|Gammaproteobacteria,1JAUM@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	EG	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily	-	-	-	-	-	-	-	-	-	-	-	-	EamA
k141_5193_8	350688.Clos_0116	1.42e-57	185.0	COG3981@1|root,COG3981@2|Bacteria,1VA6C@1239|Firmicutes,24HZ2@186801|Clostridia,36INJ@31979|Clostridiaceae	186801|Clostridia	S	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
k141_5193_9	1121121.KB894298_gene4044	6.91e-71	233.0	COG2311@1|root,COG2311@2|Bacteria,1V12A@1239|Firmicutes,4HEWA@91061|Bacilli,26WXU@186822|Paenibacillaceae	91061|Bacilli	S	Protein of unknown function (DUF1624)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1624,DUF418
k141_5193_10	760568.Desku_1641	5.17e-45	164.0	COG1609@1|root,COG1609@2|Bacteria,1TQ7K@1239|Firmicutes,247M2@186801|Clostridia	186801|Clostridia	K	Periplasmic binding protein LacI transcriptional regulator	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
k141_5193_11	318464.IO99_15795	4.73e-55	186.0	COG0537@1|root,COG0537@2|Bacteria,1V83D@1239|Firmicutes,24PYH@186801|Clostridia,36S18@31979|Clostridiaceae	186801|Clostridia	FG	Domain of unknown function (DUF4269)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4269
k141_5193_12	1121289.JHVL01000001_gene1981	2.03e-31	126.0	2EDKF@1|root,337GA@2|Bacteria,1VJWG@1239|Firmicutes,24NU6@186801|Clostridia,36MH9@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_5193_14	86416.Clopa_0492	8.55e-05	51.6	2EJKN@1|root,33DBJ@2|Bacteria,1VKME@1239|Firmicutes,24HG3@186801|Clostridia,36IW9@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_5193_15	500633.CLOHIR_00851	5.38e-40	146.0	COG2013@1|root,COG2013@2|Bacteria,1TP7N@1239|Firmicutes,249B4@186801|Clostridia,25SWR@186804|Peptostreptococcaceae	186801|Clostridia	S	Mitochondrial biogenesis AIM24	-	-	-	-	-	-	-	-	-	-	-	-	AIM24
k141_5193_16	936573.HMPREF1147_1149	7.72e-24	95.5	2CJFJ@1|root,32S9X@2|Bacteria,1V45F@1239|Firmicutes,4H8M2@909932|Negativicutes	909932|Negativicutes	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_5193_17	500633.CLOHIR_00851	9.46e-39	144.0	COG2013@1|root,COG2013@2|Bacteria,1TP7N@1239|Firmicutes,249B4@186801|Clostridia,25SWR@186804|Peptostreptococcaceae	186801|Clostridia	S	Mitochondrial biogenesis AIM24	-	-	-	-	-	-	-	-	-	-	-	-	AIM24
k141_1506_2	345073.VC395_2553	0.0	1344.0	COG1391@1|root,COG1391@2|Bacteria,1MU4I@1224|Proteobacteria,1RP9N@1236|Gammaproteobacteria,1XSHU@135623|Vibrionales	135623|Vibrionales	H	Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell	glnE	GO:0000820,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006521,GO:0006541,GO:0006542,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008882,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0010565,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0019752,GO:0031323,GO:0033238,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050789,GO:0050794,GO:0051171,GO:0062012,GO:0065007,GO:0070566,GO:0071704,GO:0080090,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.7.42,2.7.7.89	ko:K00982	-	-	-	-	ko00000,ko01000	-	-	-	GlnD_UR_UTase,GlnE
k141_3559_1	439235.Dalk_1533	3.63e-118	347.0	COG0601@1|root,COG0601@2|Bacteria,1MU8Z@1224|Proteobacteria,42P18@68525|delta/epsilon subdivisions,2WJNV@28221|Deltaproteobacteria,2MIT2@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
k141_3559_2	1379281.AVAG01000041_gene850	1.68e-165	469.0	COG1173@1|root,COG1173@2|Bacteria,1MUG0@1224|Proteobacteria,42PTR@68525|delta/epsilon subdivisions,2WJDG@28221|Deltaproteobacteria,2M9HR@213115|Desulfovibrionales	28221|Deltaproteobacteria	EP	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
k141_3559_3	207559.Dde_0272	6.22e-150	431.0	COG0444@1|root,COG0444@2|Bacteria,1R4KB@1224|Proteobacteria,42M3F@68525|delta/epsilon subdivisions,2WJ32@28221|Deltaproteobacteria,2M7V3@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	Belongs to the ABC transporter superfamily	oppD	-	-	ko:K02031,ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
k141_3559_4	1379281.AVAG01000041_gene852	2.35e-165	471.0	COG4608@1|root,COG4608@2|Bacteria,1NU4K@1224|Proteobacteria,42TDH@68525|delta/epsilon subdivisions,2WIQT@28221|Deltaproteobacteria,2M7X7@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
k141_3559_5	96561.Dole_2105	9.63e-176	517.0	COG0394@1|root,COG3829@1|root,COG0394@2|Bacteria,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,42MFH@68525|delta/epsilon subdivisions,2WIRW@28221|Deltaproteobacteria,2MIJ9@213118|Desulfobacterales	28221|Deltaproteobacteria	KT	Bacterial regulatory protein, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,PAS,PAS_9,Sigma54_activat
k141_2840_1	1265505.ATUG01000002_gene2421	1.92e-56	177.0	COG0347@1|root,COG0347@2|Bacteria,1RIX2@1224|Proteobacteria,42SFQ@68525|delta/epsilon subdivisions,2WPG3@28221|Deltaproteobacteria,2MKDZ@213118|Desulfobacterales	28221|Deltaproteobacteria	K	Belongs to the P(II) protein family	-	-	-	ko:K02589	-	-	-	-	ko00000	-	-	-	P-II
k141_2840_2	1265505.ATUG01000002_gene2420	2.68e-65	201.0	COG0347@1|root,COG0347@2|Bacteria,1RKW3@1224|Proteobacteria,42SE6@68525|delta/epsilon subdivisions,2WP2V@28221|Deltaproteobacteria,2MK52@213118|Desulfobacterales	28221|Deltaproteobacteria	K	Belongs to the P(II) protein family	-	-	-	ko:K02590	-	-	-	-	ko00000	-	-	-	P-II
k141_2840_3	879212.DespoDRAFT_03280	8.15e-16	76.6	COG2710@1|root,COG2710@2|Bacteria,1MVY2@1224|Proteobacteria,42MMI@68525|delta/epsilon subdivisions,2WJZI@28221|Deltaproteobacteria,2MJBI@213118|Desulfobacterales	28221|Deltaproteobacteria	C	molybdenum-iron protein alpha chain	nifD	-	1.18.6.1	ko:K02586	ko00625,ko00910,ko01100,ko01120,map00625,map00910,map01100,map01120	M00175	R05185,R05496	RC00002,RC01395,RC02891	ko00000,ko00001,ko00002,ko01000	-	-	-	Oxidored_nitro
k141_1507_1	1214101.BN159_0652	3.51e-09	62.8	COG3250@1|root,COG3250@2|Bacteria,2GMAT@201174|Actinobacteria	201174|Actinobacteria	G	Belongs to the glycosyl hydrolase 2 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N,Laminin_G_3,PA14
k141_4611_1	340177.Cag_0616	4.85e-28	127.0	COG3210@1|root,COG3210@2|Bacteria	2|Bacteria	U	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,Big_3_2,CHU_C,Flg_new,LRR_5
k141_3905_1	675816.VIA_000664	1.81e-204	580.0	COG0706@1|root,COG0706@2|Bacteria,1MV5M@1224|Proteobacteria,1RMH1@1236|Gammaproteobacteria,1XU5N@135623|Vibrionales	135623|Vibrionales	U	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins	yidC	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP,YidC_periplas
k141_3906_1	55601.VANGNB10_cI2628c	1.15e-51	174.0	COG0745@1|root,COG0745@2|Bacteria,1QC0H@1224|Proteobacteria,1RNF6@1236|Gammaproteobacteria,1XVUG@135623|Vibrionales	135623|Vibrionales	T	COG0784 FOG CheY-like receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
k141_3560_2	177437.HRM2_26840	3.67e-299	827.0	COG0504@1|root,COG0504@2|Bacteria,1MUIT@1224|Proteobacteria,42MEU@68525|delta/epsilon subdivisions,2WJ0F@28221|Deltaproteobacteria,2MHTP@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1276	CTP_synth_N,GATase
k141_3560_3	933262.AXAM01000002_gene525	1.15e-12	68.6	COG0449@1|root,COG0449@2|Bacteria,1MW4K@1224|Proteobacteria,42KZ7@68525|delta/epsilon subdivisions,2WJP6@28221|Deltaproteobacteria,2MIWZ@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	iAF987.Gmet_1487	GATase_6,SIS
k141_1508_1	584708.Apau_0285	9.18e-55	192.0	COG0392@1|root,COG2898@1|root,COG0392@2|Bacteria,COG2898@2|Bacteria,3TAI7@508458|Synergistetes	508458|Synergistetes	S	Uncharacterised conserved protein (DUF2156)	-	-	2.3.2.3	ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	M00726	-	-	ko00000,ko00001,ko00002,ko01000,ko01504	2.A.1.3.37	-	-	DUF2156,LPG_synthase_TM
k141_1508_2	290512.Paes_0900	4.97e-130	393.0	COG0659@1|root,COG0659@2|Bacteria,1FDMM@1090|Chlorobi	1090|Chlorobi	P	PFAM Sulfate transporter antisigma-factor antagonist STAS	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
k141_5196_2	717605.Theco_2587	1.74e-06	59.3	COG0367@1|root,COG0367@2|Bacteria,1TRPB@1239|Firmicutes,4HA44@91061|Bacilli,26S66@186822|Paenibacillaceae	91061|Bacilli	E	Asparagine synthase	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
k141_3277_2	1122599.AUGR01000001_gene260	1.86e-15	82.0	COG0834@1|root,COG2199@1|root,COG0834@2|Bacteria,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,1T245@1236|Gammaproteobacteria,1XJ38@135619|Oceanospirillales	135619|Oceanospirillales	T	GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,NMT1,SBP_bac_3
k141_2595_1	436308.Nmar_1008	2.24e-178	535.0	COG0458@1|root,COG0624@1|root,arCOG01107@2157|Archaea,arCOG01596@2157|Archaea	2157|Archaea	EF	ATP-grasp domain	cxp2	-	3.4.17.11,3.5.1.18,6.3.2.4	ko:K01295,ko:K01439,ko:K01921,ko:K16181	ko00300,ko00473,ko00550,ko01100,ko01120,ko01230,ko01502,map00300,map00473,map00550,map01100,map01120,map01230,map01502	M00016	R01150,R02734,R10011	RC00064,RC00090,RC00096,RC00141	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011	-	-	-	ATP-grasp_3,CPSase_L_D2,Dala_Dala_lig_C,M20_dimer,Peptidase_M20
k141_2595_2	123214.PERMA_1251	5.07e-145	427.0	COG0405@1|root,COG0405@2|Bacteria,2G3M5@200783|Aquificae	2|Bacteria	E	Gamma-glutamyltranspeptidase	-	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
k141_2909_2	1120705.FG95_01294	5.55e-26	113.0	2DNBF@1|root,32WM0@2|Bacteria,1R51Z@1224|Proteobacteria,2TWWZ@28211|Alphaproteobacteria,2KEES@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	VPEP
k141_5003_1	55601.VANGNB10_cII0578	1.77e-126	374.0	COG4974@1|root,COG4974@2|Bacteria,1NY1A@1224|Proteobacteria,1RN33@1236|Gammaproteobacteria,1XTA8@135623|Vibrionales	135623|Vibrionales	L	Transposase ISVa5 (IS66-family	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS66,DDE_Tnp_IS66_C,LZ_Tnp_IS66,zf-IS66
k141_1565_1	449673.BACSTE_01947	8.79e-09	59.3	COG3344@1|root,COG3344@2|Bacteria,4NGGU@976|Bacteroidetes,2FQ8T@200643|Bacteroidia,4AMV3@815|Bacteroidaceae	976|Bacteroidetes	L	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	2.7.7.49	ko:K00986	-	-	-	-	ko00000,ko01000	-	-	-	GIIM,HNH,RVT_1,RVT_N
k141_1305_2	883.DvMF_2788	6.86e-136	389.0	COG1126@1|root,COG1126@2|Bacteria,1MU9Q@1224|Proteobacteria,42M0S@68525|delta/epsilon subdivisions,2WITR@28221|Deltaproteobacteria,2M7ZW@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	PFAM ABC transporter related	-	-	3.6.3.21	ko:K02028,ko:K10038	ko02010,map02010	M00227,M00236	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.3,3.A.1.3.2	-	-	ABC_tran
k141_1305_3	1379281.AVAG01000017_gene983	6.08e-169	475.0	COG0834@1|root,COG0834@2|Bacteria,1MVT6@1224|Proteobacteria,42QIN@68525|delta/epsilon subdivisions,2WKVZ@28221|Deltaproteobacteria,2M97B@213115|Desulfovibrionales	28221|Deltaproteobacteria	ET	belongs to the bacterial solute-binding protein 3 family	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
k141_1305_4	1121441.AUCX01000006_gene841	8.1e-228	649.0	COG0765@1|root,COG0765@2|Bacteria,1MV3I@1224|Proteobacteria,42Q6W@68525|delta/epsilon subdivisions,2WKMV@28221|Deltaproteobacteria,2M8AI@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	TIGRFAM polar amino acid ABC transporter, inner membrane subunit	-	-	-	ko:K02029,ko:K10002	ko02010,ko02020,map02010,map02020	M00230,M00236	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3,3.A.1.3.19,3.A.1.3.4	-	-	BPD_transp_1
k141_2017_2	55601.VANGNB10_cI1876c	7.39e-114	333.0	COG3143@1|root,COG3143@2|Bacteria,1NIV6@1224|Proteobacteria,1RNG2@1236|Gammaproteobacteria,1XURP@135623|Vibrionales	135623|Vibrionales	NT	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)	cheZ	-	-	ko:K03414	ko02030,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheZ
k141_2017_3	55601.VANGNB10_cI1875c	1.31e-152	460.0	COG0643@1|root,COG2198@1|root,COG3266@1|root,COG0643@2|Bacteria,COG2198@2|Bacteria,COG3266@2|Bacteria,1MUAG@1224|Proteobacteria,1RMS6@1236|Gammaproteobacteria,1XT18@135623|Vibrionales	135623|Vibrionales	NT	COG0643 Chemotaxis protein histidine kinase and related kinases	cheA	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt
k141_3725_1	349521.HCH_00727	1.64e-89	271.0	292MS@1|root,2ZQ5N@2|Bacteria,1N3H9@1224|Proteobacteria,1SGA5@1236|Gammaproteobacteria,1XQTS@135619|Oceanospirillales	135619|Oceanospirillales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_3725_2	1077285.AGDG01000004_gene2244	3.56e-71	224.0	COG0457@1|root,COG0457@2|Bacteria,4NKC9@976|Bacteroidetes,2FPK0@200643|Bacteroidia,4APBP@815|Bacteroidaceae	976|Bacteroidetes	S	SMI1-KNR4 cell-wall	-	-	-	-	-	-	-	-	-	-	-	-	SUKH_6
k141_3725_4	1206744.BAGL01000002_gene4136	0.000299	44.3	COG0500@1|root,COG2226@2|Bacteria,2GP9N@201174|Actinobacteria,4G1JC@85025|Nocardiaceae	201174|Actinobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
k141_4006_2	362418.IW19_00060	8.68e-05	50.8	COG3595@1|root,COG3595@2|Bacteria,4NSAQ@976|Bacteroidetes,1I1B3@117743|Flavobacteriia,2NTX1@237|Flavobacterium	976|Bacteroidetes	S	Putative auto-transporter adhesin, head GIN domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF2807
k141_4006_4	1348635.BBJY01000003_gene3842	1.3e-211	586.0	COG0583@1|root,COG0583@2|Bacteria,1RG9S@1224|Proteobacteria,1S4W4@1236|Gammaproteobacteria,1XSVI@135623|Vibrionales	135623|Vibrionales	K	Bacterial regulatory helix-turn-helix protein, lysR family	-	-	-	ko:K03566	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_1,LysR_substrate
k141_4006_5	571.MC52_18745	1.65e-117	347.0	COG0697@1|root,COG0697@2|Bacteria,1MWSU@1224|Proteobacteria,1RSF8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	EG	Permeases of the drug metabolite transporter (DMT) superfamily	Z012_01315	-	-	-	-	-	-	-	-	-	-	-	EamA
k141_4006_6	745411.B3C1_00060	6.09e-101	304.0	COG0491@1|root,COG0491@2|Bacteria,1P5NJ@1224|Proteobacteria,1S1CZ@1236|Gammaproteobacteria,1J740@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	COG0491 Zn-dependent hydrolases, including glyoxylases	-	-	3.5.2.6	ko:K17837	ko01501,map01501	-	R06363	RC01499	ko00000,ko00001,ko01000	-	-	-	Lactamase_B
k141_4006_7	314282.PCNPT3_12370	1.54e-117	342.0	2EX86@1|root,33QIY@2|Bacteria,1NTWV@1224|Proteobacteria,1SMH3@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_4006_8	675815.VOA_001241	2.83e-89	268.0	COG1280@1|root,COG1280@2|Bacteria,1MX0K@1224|Proteobacteria,1RP43@1236|Gammaproteobacteria,1Y2QA@135623|Vibrionales	135623|Vibrionales	E	LysE type translocator	-	-	-	-	-	-	-	-	-	-	-	-	LysE
k141_4006_9	314282.PCNPT3_12380	2.13e-110	324.0	COG2872@1|root,COG2872@2|Bacteria,1MY0P@1224|Proteobacteria,1SBU1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	tRNA synthetases class II (A)	-	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2c,tRNA_SAD
k141_4006_10	675812.VHA_001406	3.01e-49	164.0	29QIV@1|root,30BIC@2|Bacteria,1RM1Y@1224|Proteobacteria,1T0X8@1236|Gammaproteobacteria,1XYKH@135623|Vibrionales	135623|Vibrionales	S	2OG-Fe(II) oxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	2OG-FeII_Oxy_3
k141_4006_11	675812.VHA_001406	1.86e-81	248.0	29QIV@1|root,30BIC@2|Bacteria,1RM1Y@1224|Proteobacteria,1T0X8@1236|Gammaproteobacteria,1XYKH@135623|Vibrionales	135623|Vibrionales	S	2OG-Fe(II) oxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	2OG-FeII_Oxy_3
k141_1306_2	518766.Rmar_1445	2.81e-43	157.0	COG3573@1|root,COG3573@2|Bacteria,4NGG1@976|Bacteroidetes	976|Bacteroidetes	S	Proposed role in polysaccahride synthesis	-	-	-	ko:K07077	-	-	-	-	ko00000	-	-	-	FAD_binding_2
k141_2018_1	555779.Dthio_PD0230	2.45e-36	142.0	COG0210@1|root,COG0210@2|Bacteria,1PG7E@1224|Proteobacteria,43796@68525|delta/epsilon subdivisions,2X2CF@28221|Deltaproteobacteria,2MEK1@213115|Desulfovibrionales	28221|Deltaproteobacteria	L	UvrD-like helicase C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	UvrD_C
k141_2343_1	1280001.BAOA01000126_gene1154	4.27e-54	180.0	COG3110@1|root,COG3110@2|Bacteria,1RK33@1224|Proteobacteria,1RZRX@1236|Gammaproteobacteria,1XWDI@135623|Vibrionales	135623|Vibrionales	S	Belongs to the UPF0319 family	SO3571	-	-	ko:K09909	-	-	-	-	ko00000	-	-	-	DUF2057
k141_2343_2	1227352.C173_26157	2.14e-10	64.7	COG1670@1|root,COG1670@2|Bacteria,1V26J@1239|Firmicutes,4HG0M@91061|Bacilli,26VVI@186822|Paenibacillaceae	91061|Bacilli	J	Acetyltransferases, including N-acetylases of ribosomal proteins	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
k141_4306_1	675817.VDA_003276	9.25e-91	284.0	COG0006@1|root,COG0006@2|Bacteria,1MUZS@1224|Proteobacteria,1RPQD@1236|Gammaproteobacteria,1XST4@135623|Vibrionales	135623|Vibrionales	E	COG0006 Xaa-Pro aminopeptidase	ampP	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Creatinase_N,Creatinase_N_2,Peptidase_M24,Peptidase_M24_C
k141_4306_2	754436.JCM19237_1939	1.81e-38	134.0	COG2801@1|root,COG2801@2|Bacteria,1MVN5@1224|Proteobacteria,1RP6D@1236|Gammaproteobacteria,1XYIX@135623|Vibrionales	135623|Vibrionales	L	Integrase core domain	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	rve,rve_3
k141_4306_3	1188252.AJYK01000024_gene2902	4.48e-64	218.0	COG0352@1|root,COG0352@2|Bacteria,1QTW3@1224|Proteobacteria,1T1YB@1236|Gammaproteobacteria,1XSWF@135623|Vibrionales	135623|Vibrionales	H	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)	thiE	-	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	TMP-TENI
k141_4306_4	1348635.BBJY01000028_gene2093	0.0	1027.0	COG0422@1|root,COG0422@2|Bacteria,1MUVV@1224|Proteobacteria,1RP1F@1236|Gammaproteobacteria,1XSWD@135623|Vibrionales	135623|Vibrionales	H	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction	thiC	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.99.17	ko:K03147	ko00730,ko01100,map00730,map01100	M00127	R03472	RC03251,RC03252	ko00000,ko00001,ko00002,ko01000	-	-	-	ThiC-associated,ThiC_Rad_SAM
k141_4306_5	223926.28808054	4.85e-73	220.0	COG0239@1|root,COG0239@2|Bacteria,1MZNH@1224|Proteobacteria,1S8RQ@1236|Gammaproteobacteria,1XXA0@135623|Vibrionales	135623|Vibrionales	D	Important for reducing fluoride concentration in the cell, thus reducing its toxicity	crcB	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425	-	ko:K06199	-	-	-	-	ko00000,ko02000	1.A.43.1,1.A.43.2,1.A.43.3	-	-	CRCB
k141_4306_6	1219072.VHA01S_054_00160	4.78e-19	82.8	COG3335@1|root,COG3335@2|Bacteria,1RCFZ@1224|Proteobacteria,1S2QS@1236|Gammaproteobacteria,1XWK6@135623|Vibrionales	135623|Vibrionales	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3
k141_4306_7	1082933.MEA186_25062	0.000208	42.4	COG3335@1|root,COG3335@2|Bacteria,1RB1C@1224|Proteobacteria,2U367@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3
k141_5004_1	1187848.AJYQ01000156_gene3810	2.23e-180	531.0	COG5280@1|root,COG5280@2|Bacteria,1QEC1@1224|Proteobacteria,1TAY3@1236|Gammaproteobacteria,1XV28@135623|Vibrionales	135623|Vibrionales	S	Phage tail tape measure protein TP901	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_3278_1	933262.AXAM01000022_gene3227	2.04e-121	365.0	COG1960@1|root,COG1960@2|Bacteria,1MU20@1224|Proteobacteria,42N2H@68525|delta/epsilon subdivisions,2WMIR@28221|Deltaproteobacteria,2MIIF@213118|Desulfobacterales	28221|Deltaproteobacteria	I	Acyl-CoA dehydrogenase N terminal	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_C,Acyl-CoA_dh_M,Acyl-CoA_dh_N,AcylCoA_DH_N
k141_1307_1	207559.Dde_3325	3.41e-126	367.0	COG3221@1|root,COG3221@2|Bacteria,1MXD8@1224|Proteobacteria,42R3U@68525|delta/epsilon subdivisions,2WMPK@28221|Deltaproteobacteria,2MAM3@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	phosphonate ABC transporter, periplasmic phosphonate binding protein	-	-	-	ko:K02044	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	Phosphonate-bd
k141_3726_1	1121459.AQXE01000001_gene2685	7.27e-101	306.0	COG2113@1|root,COG2113@2|Bacteria,1RADA@1224|Proteobacteria,42YZW@68525|delta/epsilon subdivisions,2WUKT@28221|Deltaproteobacteria,2MET7@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	Substrate binding domain of ABC-type glycine betaine transport system	-	-	-	ko:K02002	ko02010,map02010	M00208	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	OpuAC
k141_3726_2	768066.HELO_2747	4.85e-10	58.9	COG3246@1|root,COG3246@2|Bacteria,1MZTP@1224|Proteobacteria,1RRUP@1236|Gammaproteobacteria,1XMT9@135619|Oceanospirillales	135619|Oceanospirillales	S	quinone reductase	-	-	-	-	-	-	-	-	-	-	-	-	BKACE
k141_2911_2	520999.PROVALCAL_02261	1.69e-273	769.0	COG0187@1|root,COG0187@2|Bacteria,1MVH1@1224|Proteobacteria,1RMCI@1236|Gammaproteobacteria,3Z7HT@586|Providencia	1236|Gammaproteobacteria	L	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule	parE	GO:0000819,GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006265,GO:0006276,GO:0006725,GO:0006807,GO:0006996,GO:0007049,GO:0007059,GO:0007062,GO:0008094,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017111,GO:0022402,GO:0030541,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0098813,GO:0140097,GO:1901360	-	ko:K02622	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
k141_2345_1	1265505.ATUG01000001_gene3660	5.53e-92	285.0	COG1639@1|root,COG1871@1|root,COG1639@2|Bacteria,COG1871@2|Bacteria,1R5J4@1224|Proteobacteria,42M75@68525|delta/epsilon subdivisions,2WMEB@28221|Deltaproteobacteria,2MISI@213118|Desulfobacterales	28221|Deltaproteobacteria	NT	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis	-	-	-	-	-	-	-	-	-	-	-	-	CheD,HDOD
k141_2019_1	1479237.JMLY01000001_gene3311	1.22e-159	476.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,1RMYC@1236|Gammaproteobacteria,464UX@72275|Alteromonadaceae	1236|Gammaproteobacteria	P	COG0474 Cation transport ATPase	-	-	-	-	-	-	-	-	-	-	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase
k141_5005_1	272560.BPSS1103	8.06e-62	208.0	COG1653@1|root,COG1653@2|Bacteria,1P3FA@1224|Proteobacteria,2WE2K@28216|Betaproteobacteria,1KBH0@119060|Burkholderiaceae	28216|Betaproteobacteria	G	Mannan-binding protein	-	-	2.5.1.2	ko:K10811	ko00730,map00730	-	R02863	RC00224,RC00795	ko00000,ko00001,ko01000	-	-	-	MVL
k141_3279_1	316275.VSAL_I0762	4.82e-81	254.0	COG0733@1|root,COG0733@2|Bacteria,1MUZJ@1224|Proteobacteria,1RPCT@1236|Gammaproteobacteria,1XT5X@135623|Vibrionales	135623|Vibrionales	S	COG0733 Na -dependent transporters of the SNF family	-	-	-	ko:K03308	-	-	-	-	ko00000	2.A.22.4,2.A.22.5	-	-	SNF
k141_2597_2	314292.VAS14_11629	5.4e-167	488.0	COG1882@1|root,COG1882@2|Bacteria,1MWBF@1224|Proteobacteria,1SM64@1236|Gammaproteobacteria,1XT8B@135623|Vibrionales	135623|Vibrionales	C	Pyruvate formate lyase-like	-	-	2.3.1.54	ko:K00656	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	-	R00212,R06987	RC00004,RC01181,RC02742,RC02833	ko00000,ko00001,ko01000	-	-	-	Gly_radical,PFL-like
k141_4307_1	595460.RRSWK_03194	3.85e-102	318.0	COG2239@1|root,COG2239@2|Bacteria,2IYCZ@203682|Planctomycetes	203682|Planctomycetes	P	Acts as a magnesium transporter	-	-	-	ko:K06213	-	-	-	-	ko00000,ko02000	1.A.26.1	-	-	CBS,MgtE,MgtE_N
k141_2346_1	563192.HMPREF0179_00055	1.98e-77	256.0	COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,42MFC@68525|delta/epsilon subdivisions,2WJ4H@28221|Deltaproteobacteria,2MA1I@213115|Desulfovibrionales	28221|Deltaproteobacteria	H	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor	bioA	-	2.6.1.62	ko:K00833	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03231	RC00006,RC00887	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	AAA_26,Aminotran_3
k141_1567_1	1265503.KB905166_gene745	4.72e-65	228.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,2Q5VA@267889|Colwelliaceae	1236|Gammaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K18138	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
k141_909_3	1188252.AJYK01000065_gene2529	2.95e-22	89.0	2CK10@1|root,32SBA@2|Bacteria,1N8PV@1224|Proteobacteria,1S938@1236|Gammaproteobacteria,1XYF4@135623|Vibrionales	135623|Vibrionales	S	Protein of unknown function (DUF2498)	STY1335	-	-	-	-	-	-	-	-	-	-	-	DUF2498
k141_909_5	675813.VIB_001094	1.04e-16	73.9	COG3133@1|root,COG3133@2|Bacteria,1RIY9@1224|Proteobacteria,1S819@1236|Gammaproteobacteria,1XX6N@135623|Vibrionales	135623|Vibrionales	M	Glycine zipper 2TM domain	slyB	-	-	ko:K06077	-	-	-	-	ko00000	-	-	-	Rick_17kDa_Anti
k141_4008_2	55601.VANGNB10_cI1722	1.26e-60	198.0	COG4006@1|root,COG4006@2|Bacteria,1RFA6@1224|Proteobacteria,1S6RM@1236|Gammaproteobacteria,1XU5U@135623|Vibrionales	135623|Vibrionales	S	Domain of unknown function (DUF1887)	VV2376	-	-	-	-	-	-	-	-	-	-	-	DUF1887
k141_2912_1	879212.DespoDRAFT_00394	3.11e-68	226.0	COG0592@1|root,COG0592@2|Bacteria,1MVD9@1224|Proteobacteria,42NQW@68525|delta/epsilon subdivisions,2WJZM@28221|Deltaproteobacteria,2MHS9@213118|Desulfobacterales	28221|Deltaproteobacteria	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	dnaN	-	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
k141_2347_1	96561.Dole_2798	2.97e-41	155.0	COG2366@1|root,COG2366@2|Bacteria,1MVMH@1224|Proteobacteria,42M9A@68525|delta/epsilon subdivisions,2WJ3Y@28221|Deltaproteobacteria,2MJBT@213118|Desulfobacterales	28221|Deltaproteobacteria	S	PFAM peptidase S45 penicillin amidase	-	-	3.5.1.11,3.5.1.97	ko:K01434,ko:K07116	ko00311,ko01130,map00311,map01130	-	R02170	RC00166,RC00328	ko00000,ko00001,ko01000,ko01002	-	-	-	Penicil_amidase
k141_3728_1	1121342.AUCO01000008_gene93	6.56e-78	246.0	COG1454@1|root,COG1454@2|Bacteria,1TQMF@1239|Firmicutes,24828@186801|Clostridia,36F1E@31979|Clostridiaceae	186801|Clostridia	C	alcohol dehydrogenase	4hbD	-	1.1.1.61	ko:K18120	ko00650,ko01100,ko01200,map00650,map01100,map01200	-	R01644	RC00087	ko00000,ko00001,ko01000	-	-	-	Fe-ADH
k141_2020_1	1209984.BN978_02015	1.31e-50	178.0	COG3335@1|root,COG3415@1|root,COG3335@2|Bacteria,COG3415@2|Bacteria,2GJQI@201174|Actinobacteria,234RT@1762|Mycobacteriaceae	201174|Actinobacteria	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,HTH_32
k141_910_1	1123228.AUIH01000038_gene2761	2.5e-42	165.0	COG3210@1|root,COG3210@2|Bacteria,1QQD4@1224|Proteobacteria,1RZ1D@1236|Gammaproteobacteria	1236|Gammaproteobacteria	U	Mandelate Racemase Muconate Lactonizing	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_3280_2	1172562.HCN_1867	2.87e-07	55.5	COG1629@1|root,COG1629@2|Bacteria,1QV18@1224|Proteobacteria,42PXD@68525|delta/epsilon subdivisions,2YNPS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	TonB-dependent receptor plug domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Plug
k141_4310_1	1284352.AOIG01000022_gene3767	3.39e-31	123.0	COG0079@1|root,COG0079@2|Bacteria,1TPUV@1239|Firmicutes,4HA1H@91061|Bacilli,26S6U@186822|Paenibacillaceae	91061|Bacilli	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily	hisC	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
k141_2348_1	96561.Dole_1631	3.48e-111	327.0	COG1192@1|root,COG1192@2|Bacteria,1MV43@1224|Proteobacteria,42MTF@68525|delta/epsilon subdivisions,2WJ6X@28221|Deltaproteobacteria,2MHMY@213118|Desulfobacterales	28221|Deltaproteobacteria	D	PFAM CobQ CobB MinD ParA nucleotide binding domain	soj	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
k141_2348_2	698769.JFBD01000054_gene955	3.26e-64	209.0	COG1475@1|root,COG1475@2|Bacteria,1TQ2B@1239|Firmicutes,4H9TB@91061|Bacilli,4C523@84406|Virgibacillus	91061|Bacilli	K	ParB-like nuclease domain	spo0J	GO:0005575,GO:0005622,GO:0005623,GO:0007059,GO:0008150,GO:0009295,GO:0009987,GO:0022603,GO:0042173,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0043937,GO:0043938,GO:0044424,GO:0044464,GO:0045595,GO:0045597,GO:0045881,GO:0048518,GO:0048522,GO:0050789,GO:0050793,GO:0050794,GO:0051094,GO:0065007	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	HTH_3,KorB,ParBc
k141_4311_1	1321786.HMPREF1992_00145	0.000516	42.4	COG0326@1|root,COG0642@1|root,COG0326@2|Bacteria,COG0642@2|Bacteria,1UJW7@1239|Firmicutes,4H7IM@909932|Negativicutes	909932|Negativicutes	H	ATPase histidine kinase DNA gyrase B HSP90 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_3
k141_2598_1	879212.DespoDRAFT_02273	2.22e-147	432.0	COG0206@1|root,COG0206@2|Bacteria,1MV2X@1224|Proteobacteria,42MHK@68525|delta/epsilon subdivisions,2WJAZ@28221|Deltaproteobacteria,2MHTR@213118|Desulfobacterales	28221|Deltaproteobacteria	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
k141_2598_2	177437.HRM2_12750	7.77e-136	402.0	COG0849@1|root,COG0849@2|Bacteria,1MUSR@1224|Proteobacteria,42MS2@68525|delta/epsilon subdivisions,2WIQ0@28221|Deltaproteobacteria,2MHV9@213118|Desulfobacterales	28221|Deltaproteobacteria	D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring	ftsA	-	-	ko:K03590	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036,ko04812	-	-	-	FtsA,SHS2_FTSA
k141_1568_1	595494.Tola_3107	2.1e-68	223.0	COG2272@1|root,COG2272@2|Bacteria,1MVQZ@1224|Proteobacteria,1RPFW@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	Belongs to the type-B carboxylesterase lipase family	pnbA	-	-	ko:K03929	-	-	-	-	ko00000,ko01000	-	CE10	-	COesterase
k141_1568_2	595494.Tola_3107	2.2e-134	400.0	COG2272@1|root,COG2272@2|Bacteria,1MVQZ@1224|Proteobacteria,1RPFW@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	Belongs to the type-B carboxylesterase lipase family	pnbA	-	-	ko:K03929	-	-	-	-	ko00000,ko01000	-	CE10	-	COesterase
k141_1568_3	675816.VIA_000824	1.64e-116	349.0	COG1030@1|root,COG1030@2|Bacteria,1MUJN@1224|Proteobacteria,1RN3U@1236|Gammaproteobacteria,1XV48@135623|Vibrionales	135623|Vibrionales	O	COG1030 Membrane-bound serine protease (ClpP class)	-	-	-	ko:K07403	-	-	-	-	ko00000	-	-	-	NfeD
k141_3281_1	1123518.ARWI01000001_gene233	1.4e-160	455.0	COG0180@1|root,COG0180@2|Bacteria,1MV4T@1224|Proteobacteria,1RNDC@1236|Gammaproteobacteria,460SY@72273|Thiotrichales	72273|Thiotrichales	J	PFAM tRNA synthetases class I (W and Y)	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
k141_3287_4	945543.VIBR0546_01208	6.95e-205	571.0	COG1494@1|root,COG1494@2|Bacteria,1MUB1@1224|Proteobacteria,1RR0E@1236|Gammaproteobacteria,1XTI1@135623|Vibrionales	135623|Vibrionales	G	COG1494 Fructose-1,6-bisphosphatase sedoheptulose 1,7-bisphosphatase and related proteins	glpX	-	3.1.3.11	ko:K02446	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00165,M00167	R00762,R04780	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FBPase_glpX
k141_3287_5	55601.VANGNB10_cI2437c	1.24e-211	587.0	COG0205@1|root,COG0205@2|Bacteria,1MVN3@1224|Proteobacteria,1RMVY@1236|Gammaproteobacteria,1XTJ3@135623|Vibrionales	135623|Vibrionales	F	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	pfkA	GO:0003674,GO:0003824,GO:0003872,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008443,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019200,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046835,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0061615,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576	2.7.1.11	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	M00001,M00345	R00756,R03236,R03237,R03238,R03239,R04779	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	-	-	-	PFK
k141_3287_6	55601.VANGNB10_cI2438c	3.19e-159	452.0	COG0053@1|root,COG0053@2|Bacteria,1MUDS@1224|Proteobacteria,1RNS2@1236|Gammaproteobacteria,1XSMN@135623|Vibrionales	135623|Vibrionales	P	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	fieF	-	-	ko:K13283	-	-	-	-	ko00000,ko02000	2.A.4.7.1	-	-	Cation_efflux,ZT_dimer
k141_3287_7	1136163.M565_ctg4P181	1.71e-14	75.1	COG3678@1|root,COG3678@2|Bacteria,1RBDH@1224|Proteobacteria,1S2DT@1236|Gammaproteobacteria,1XWIC@135623|Vibrionales	135623|Vibrionales	NPTU	COG3678 P pilus assembly Cpx signaling pathway, periplasmic inhibitor zinc-resistance associated protein	cpxP	-	-	ko:K06006	-	-	-	-	ko00000,ko03110	-	-	-	LTXXQ
k141_3287_9	345073.VC395_2806	9.07e-196	558.0	COG5002@1|root,COG5002@2|Bacteria,1QUGI@1224|Proteobacteria,1T1Y9@1236|Gammaproteobacteria,1XT99@135623|Vibrionales	135623|Vibrionales	T	sensor protein	cpxA	-	2.7.13.3	ko:K07640	ko01503,ko02020,map01503,map02020	M00447,M00727,M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	CpxA_peri,HAMP,HATPase_c,HisKA
k141_3287_11	223926.28807888	2.74e-62	196.0	COG3030@1|root,COG3030@2|Bacteria,1MZJJ@1224|Proteobacteria,1S8XU@1236|Gammaproteobacteria,1XVK9@135623|Vibrionales	135623|Vibrionales	S	COG3030 Protein affecting phage T7 exclusion by the F plasmid	fxsA	-	-	ko:K07113	-	-	-	-	ko00000	-	-	-	FxsA
k141_3287_12	1219065.VPR01S_26_00400	6.53e-193	564.0	COG2199@1|root,COG2199@2|Bacteria,1P82T@1224|Proteobacteria,1S7Z1@1236|Gammaproteobacteria,1XZQI@135623|Vibrionales	135623|Vibrionales	T	PAS domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
k141_1375_1	696281.Desru_0529	2.1e-28	115.0	COG1541@1|root,COG1541@2|Bacteria,1TQA1@1239|Firmicutes,248G9@186801|Clostridia,263YS@186807|Peptococcaceae	186801|Clostridia	H	Coenzyme F390 synthetase	paaK	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C_2,LuxC
k141_1375_2	1265505.ATUG01000002_gene1441	1.37e-22	95.5	COG1964@1|root,COG1964@2|Bacteria,1QE02@1224|Proteobacteria,42M4B@68525|delta/epsilon subdivisions,2WJDI@28221|Deltaproteobacteria,2MJ90@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Radical SAM superfamily	-	-	-	ko:K06937	-	-	-	-	ko00000,ko01000	-	-	-	Fer4_12,Fer4_14,Radical_SAM
k141_4096_2	1238450.VIBNISOn1_820097	3.9e-110	320.0	COG0164@1|root,COG0164@2|Bacteria,1RA65@1224|Proteobacteria,1RQ4B@1236|Gammaproteobacteria,1XSNB@135623|Vibrionales	135623|Vibrionales	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhB	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
k141_4096_3	674977.VMC_17830	1.08e-206	579.0	COG0763@1|root,COG0763@2|Bacteria,1MVBI@1224|Proteobacteria,1RNS1@1236|Gammaproteobacteria,1XSUV@135623|Vibrionales	135623|Vibrionales	M	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxB	GO:0003674,GO:0003824,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008194,GO:0008289,GO:0008610,GO:0008654,GO:0008915,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	2.4.1.182	ko:K00748	ko00540,ko01100,map00540,map01100	M00060	R04606	RC00005,RC00059	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT19	-	LpxB
k141_4096_4	675806.VII_001596	3.14e-104	310.0	COG1043@1|root,COG1043@2|Bacteria,1MUHQ@1224|Proteobacteria,1RPHB@1236|Gammaproteobacteria,1XSN6@135623|Vibrionales	135623|Vibrionales	M	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxA	GO:0003674,GO:0003824,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008374,GO:0008610,GO:0008654,GO:0008780,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	2.3.1.129	ko:K00677	ko00540,ko01100,ko01503,map00540,map01100,map01503	M00060	R04567	RC00039,RC00055	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Acetyltransf_11,Hexapep
k141_4096_5	345073.VC395_2365	1.89e-93	274.0	COG0764@1|root,COG0764@2|Bacteria,1RH2T@1224|Proteobacteria,1S63E@1236|Gammaproteobacteria,1XVJ6@135623|Vibrionales	135623|Vibrionales	I	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs	fabZ	GO:0003674,GO:0003824,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:0072330,GO:1901576	4.2.1.59	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121	RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FabA
k141_4096_6	29495.EA26_17360	1.88e-119	355.0	COG1044@1|root,COG1044@2|Bacteria,1MUX6@1224|Proteobacteria,1RNYI@1236|Gammaproteobacteria,1XSDH@135623|Vibrionales	135623|Vibrionales	I	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxD	GO:0003674,GO:0003824,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016746,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	2.3.1.191	ko:K02536	ko00540,ko01100,map00540,map01100	M00060	R04550	RC00039,RC00166	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hexapep,Hexapep_2,LpxD
k141_4096_7	1136163.M565_ctg1P0318	4.81e-51	168.0	COG2825@1|root,COG2825@2|Bacteria,1RD8X@1224|Proteobacteria,1RQIE@1236|Gammaproteobacteria,1XUST@135623|Vibrionales	135623|Vibrionales	M	Molecular chaperone that interacts specifically with outer membrane proteins, thus maintaining the solubility of early folding intermediates during passage through the periplasm	skp	GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944	-	ko:K06142	-	-	-	-	ko00000	-	-	-	OmpH
k141_4096_8	1219065.VPR01S_10_00620	0.0	1256.0	COG4775@1|root,COG4775@2|Bacteria,1MU0D@1224|Proteobacteria,1RMAP@1236|Gammaproteobacteria,1XTPE@135623|Vibrionales	135623|Vibrionales	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamA	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
k141_4096_9	945543.VIBR0546_19884	8.75e-218	613.0	COG0750@1|root,COG0750@2|Bacteria,1MU91@1224|Proteobacteria,1RMIX@1236|Gammaproteobacteria,1XUCN@135623|Vibrionales	135623|Vibrionales	M	Zinc metalloprotease	rseP	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_M50
k141_4096_10	55601.VANGNB10_cI2041c	2.12e-205	578.0	COG0743@1|root,COG0743@2|Bacteria,1MU4G@1224|Proteobacteria,1RNNW@1236|Gammaproteobacteria,1XT3U@135623|Vibrionales	135623|Vibrionales	I	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)	dxr	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576	1.1.1.267	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05688	RC01452	ko00000,ko00001,ko00002,ko01000	-	-	-	DXPR_C,DXP_redisom_C,DXP_reductoisom
k141_4096_11	243277.VC_2255	1.4e-116	343.0	COG0575@1|root,COG0575@2|Bacteria,1MWSV@1224|Proteobacteria,1RQ6M@1236|Gammaproteobacteria,1Y3DB@135623|Vibrionales	135623|Vibrionales	M	Cytidylyltransferase family	cdsA	-	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
k141_4096_12	243277.VC_2256	1.54e-142	406.0	COG0020@1|root,COG0020@2|Bacteria,1MVP1@1224|Proteobacteria,1RMVX@1236|Gammaproteobacteria,1XTBC@135623|Vibrionales	135623|Vibrionales	H	Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di-trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide	uppS	GO:0000270,GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006022,GO:0006023,GO:0006024,GO:0006066,GO:0006629,GO:0006720,GO:0006807,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
k141_4096_13	1219076.N646_1425	9.84e-110	318.0	COG0233@1|root,COG0233@2|Bacteria,1N66T@1224|Proteobacteria,1RN75@1236|Gammaproteobacteria,1XUSS@135623|Vibrionales	135623|Vibrionales	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
k141_31_1	1304885.AUEY01000067_gene1309	1.95e-56	201.0	COG2199@1|root,COG3706@2|Bacteria,1MXAW@1224|Proteobacteria,42NB3@68525|delta/epsilon subdivisions,2X5VB@28221|Deltaproteobacteria,2MHU8@213118|Desulfobacterales	28221|Deltaproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
k141_1376_1	1158318.ATXC01000001_gene338	8.85e-30	128.0	COG2067@1|root,COG2067@2|Bacteria,2G47R@200783|Aquificae	200783|Aquificae	I	Outer membrane protein transport protein (OMPP1/FadL/TodX)	-	-	-	ko:K06076	-	-	-	-	ko00000,ko02000	1.B.9	-	-	Toluene_X
k141_1723_1	340177.Cag_0616	3.74e-140	493.0	COG3210@1|root,COG3210@2|Bacteria	2|Bacteria	U	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,Big_3_2,CHU_C,Flg_new,LRR_5
k141_2725_2	1033737.CAEV01000092_gene1966	1.08e-36	135.0	COG1583@1|root,COG1583@2|Bacteria,1V4U6@1239|Firmicutes,24EJT@186801|Clostridia,36JPC@31979|Clostridiaceae	186801|Clostridia	L	CRISPR associated protein Cas6	-	-	-	ko:K19091	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	Cas_Cas6
k141_2725_4	1301100.HG529316_gene486	2.21e-202	604.0	COG1203@1|root,COG1203@2|Bacteria,1TQ9B@1239|Firmicutes,248UE@186801|Clostridia,36GA4@31979|Clostridiaceae	186801|Clostridia	L	CRISPR-associated helicase Cas3	cas3	-	-	ko:K07012	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	DEAD,HD,Helicase_C,ResIII
k141_2725_6	1301100.HG529316_gene491	2.8e-28	105.0	COG1343@1|root,COG1343@2|Bacteria,1VAV3@1239|Firmicutes,24NM2@186801|Clostridia,36KIF@31979|Clostridiaceae	186801|Clostridia	L	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette	cas2	-	-	ko:K09951	-	-	-	-	ko00000,ko02048	-	-	-	CRISPR_Cas2
k141_2725_7	500633.CLOHIR_00655	1.08e-134	393.0	COG1518@1|root,COG1518@2|Bacteria,1TQWG@1239|Firmicutes,24889@186801|Clostridia	186801|Clostridia	L	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette	cas1	-	-	ko:K15342	-	-	-	-	ko00000,ko02048,ko03400	-	-	-	Cas_Cas1,RVT_1
k141_2725_8	386415.NT01CX_0201	3.78e-62	196.0	COG1468@1|root,COG1468@2|Bacteria,1V3RV@1239|Firmicutes,25D41@186801|Clostridia,36U6R@31979|Clostridiaceae	186801|Clostridia	L	CRISPR-associated protein Cas4	cas4	-	3.1.12.1	ko:K07464	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	Cas_Cas4
k141_2725_9	1150621.SMUL_1143	3.23e-53	179.0	28NN3@1|root,2ZBNI@2|Bacteria,1Q06W@1224|Proteobacteria,42RPI@68525|delta/epsilon subdivisions,2YP64@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	CRISPR-associated protein Cas5	cas5h	-	-	ko:K19116	-	-	-	-	ko00000,ko02048	-	-	-	-
k141_2725_10	1118055.CAGU01000046_gene1658	1.89e-92	284.0	COG3649@1|root,COG3649@2|Bacteria,1UKQK@1239|Firmicutes,24C9C@186801|Clostridia,22H07@1570339|Peptoniphilaceae	186801|Clostridia	L	Pfam:DUF694	-	-	-	ko:K19115	-	-	-	-	ko00000,ko02048	-	-	-	Cas_Cas7
k141_2725_11	1499683.CCFF01000017_gene1488	4.88e-50	189.0	28JMD@1|root,2Z9DX@2|Bacteria,1UM68@1239|Firmicutes,24CYH@186801|Clostridia,36FSY@31979|Clostridiaceae	186801|Clostridia	-	-	csh	-	-	ko:K19114	-	-	-	-	ko00000,ko02048	-	-	-	-
k141_2725_15	1410653.JHVC01000014_gene3430	1.46e-24	99.8	COG2963@1|root,COG2963@2|Bacteria,1V4FD@1239|Firmicutes,24GUY@186801|Clostridia,36I6D@31979|Clostridiaceae	186801|Clostridia	L	hmm pf01527	-	-	-	-	-	-	-	-	-	-	-	-	HTH_28,HTH_Tnp_1
k141_2725_16	756499.Desde_1540	1.59e-40	137.0	COG1733@1|root,COG1733@2|Bacteria,1VA9M@1239|Firmicutes,24N2T@186801|Clostridia,266XR@186807|Peptococcaceae	186801|Clostridia	K	HxlR-like helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HxlR
k141_2725_17	1211817.CCAT010000084_gene1822	7.07e-48	159.0	COG2153@1|root,COG2153@2|Bacteria,1VAJY@1239|Firmicutes,24JG3@186801|Clostridia,36JM2@31979|Clostridiaceae	186801|Clostridia	S	Acetyltransferase (GNAT) domain	-	-	-	ko:K02348	-	-	-	-	ko00000	-	-	-	Acetyltransf_10
k141_2725_18	536232.CLM_1224	2.7e-250	711.0	COG0488@1|root,COG0488@2|Bacteria,1TPAX@1239|Firmicutes,247Q9@186801|Clostridia,36FYC@31979|Clostridiaceae	186801|Clostridia	S	ABC transporter	yfmR	-	-	ko:K15738	-	-	-	-	ko00000,ko02000	3.A.1.120.6	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
k141_2725_19	1499689.CCNN01000007_gene1141	1.16e-115	345.0	COG1482@1|root,COG1482@2|Bacteria,1V0PH@1239|Firmicutes,2487K@186801|Clostridia,36E6K@31979|Clostridiaceae	186801|Clostridia	G	mannose-6-phosphate isomerase, class I	manA	-	5.3.1.8	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01819	RC00376	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS19425	PMI_typeI
k141_2725_20	1408438.JADD01000010_gene1893	3.69e-39	146.0	COG0561@1|root,COG0561@2|Bacteria,1V5FB@1239|Firmicutes,4HGY8@91061|Bacilli,27EKX@186827|Aerococcaceae	91061|Bacilli	S	Sucrose-6F-phosphate phosphohydrolase	ycsE	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
k141_2725_21	326423.RBAM_033520	2.61e-60	198.0	COG1349@1|root,COG1349@2|Bacteria,1V1VH@1239|Firmicutes,4HG12@91061|Bacilli,1ZN25@1386|Bacillus	91061|Bacilli	K	DeoR C terminal sensor domain	glcR	-	-	ko:K22103	-	-	-	-	ko00000,ko03000	-	-	-	DeoRC,HTH_DeoR
k141_2725_22	572479.Hprae_1147	3.66e-24	94.0	COG4675@1|root,COG4675@2|Bacteria,1V943@1239|Firmicutes,24PFY@186801|Clostridia	186801|Clostridia	S	PFAM Tail Collar domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Collar
k141_2725_23	572479.Hprae_1147	1.39e-26	99.8	COG4675@1|root,COG4675@2|Bacteria,1V943@1239|Firmicutes,24PFY@186801|Clostridia	186801|Clostridia	S	PFAM Tail Collar domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Collar
k141_2725_24	985665.HPL003_10875	4.33e-31	112.0	COG4675@1|root,COG4675@2|Bacteria,1V943@1239|Firmicutes,4HJCC@91061|Bacilli,26YNV@186822|Paenibacillaceae	91061|Bacilli	S	Phage Tail Collar Domain	-	-	-	-	-	-	-	-	-	-	-	-	Collar
k141_4777_15	1321782.HMPREF1986_02476	1.43e-59	224.0	COG0577@1|root,COG0577@2|Bacteria,1TPHU@1239|Firmicutes,248RV@186801|Clostridia,2PSA8@265975|Oribacterium	186801|Clostridia	V	Efflux ABC transporter, permease protein	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
k141_4777_16	679200.HMPREF9333_00710	9.02e-95	285.0	COG1136@1|root,COG1136@2|Bacteria,1TQC9@1239|Firmicutes,248Z6@186801|Clostridia	186801|Clostridia	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,GAF_2
k141_4777_17	1009370.ALO_04978	1.96e-18	86.3	COG1309@1|root,COG1309@2|Bacteria,1V695@1239|Firmicutes,4H4BF@909932|Negativicutes	909932|Negativicutes	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
k141_4777_18	574087.Acear_0937	2.17e-71	238.0	COG2206@1|root,COG2206@2|Bacteria,1TS2E@1239|Firmicutes,249S8@186801|Clostridia,3WB2V@53433|Halanaerobiales	186801|Clostridia	T	PFAM HD domain	-	-	-	-	-	-	-	-	-	-	-	-	HD
k141_4777_19	1301100.HG529299_gene5191	3.99e-25	97.8	COG0316@1|root,COG0316@2|Bacteria,1VGGP@1239|Firmicutes,24HQ7@186801|Clostridia	186801|Clostridia	S	Belongs to the HesB IscA family	-	-	-	ko:K13628	-	-	-	-	ko00000,ko03016	-	-	-	Fe-S_biosyn
k141_4777_20	632245.CLP_2153	1.14e-105	311.0	COG2013@1|root,COG2013@2|Bacteria,1TPN2@1239|Firmicutes,2499B@186801|Clostridia,36E74@31979|Clostridiaceae	186801|Clostridia	S	Mitochondrial biogenesis AIM24	-	-	-	-	-	-	-	-	-	-	-	-	AIM24
k141_4777_21	1230342.CTM_13833	1.4e-14	86.3	COG0840@1|root,COG0840@2|Bacteria,1TP5A@1239|Firmicutes,247S3@186801|Clostridia,36HBC@31979|Clostridiaceae	186801|Clostridia	NT	chemotaxis	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,CZB,HAMP,MCPsignal,dCache_1
k141_4777_22	350688.Clos_0093	4.07e-148	427.0	COG2025@1|root,COG2025@2|Bacteria,1TPC8@1239|Firmicutes,247NF@186801|Clostridia,36DD9@31979|Clostridiaceae	186801|Clostridia	C	Electron transfer flavoprotein	etfA	-	1.3.1.108	ko:K03522,ko:K22432	-	-	-	-	ko00000,ko01000,ko04147	-	-	-	ETF,ETF_alpha,Fer4
k141_4777_23	350688.Clos_0637	1.16e-134	387.0	COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia,36EI7@31979|Clostridiaceae	186801|Clostridia	C	Electron transfer flavoprotein	etfB	-	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
k141_4777_24	350688.Clos_0091	2.05e-219	611.0	COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,247UB@186801|Clostridia,36DR1@31979|Clostridiaceae	186801|Clostridia	I	acyl-CoA dehydrogenase	bcd2	-	1.3.8.1	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	-	R01175,R01178,R02661,R03172,R04751	RC00052,RC00068,RC00076,RC00120,RC00148	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
k141_4777_25	1304284.L21TH_1618	3.32e-139	400.0	COG1250@1|root,COG1250@2|Bacteria,1TPJS@1239|Firmicutes,248AE@186801|Clostridia,36DG5@31979|Clostridiaceae	186801|Clostridia	I	Dehydrogenase	hbd	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
k141_4777_26	1033737.CAEV01000032_gene2157	3.29e-112	332.0	COG1024@1|root,COG1024@2|Bacteria,1TQ89@1239|Firmicutes,247RK@186801|Clostridia,36EDS@31979|Clostridiaceae	186801|Clostridia	I	Belongs to the enoyl-CoA hydratase isomerase family	crt	-	4.2.1.17	ko:K01715	ko00650,ko01200,map00650,map01200	-	R03026	RC00831	ko00000,ko00001,ko01000	-	-	-	ECH_1
k141_4777_27	386415.NT01CX_2062	3.04e-32	135.0	COG3290@1|root,COG3290@2|Bacteria,1UYTM@1239|Firmicutes,24CUA@186801|Clostridia,36FUX@31979|Clostridiaceae	186801|Clostridia	T	GHKL domain	-	-	2.7.13.3	ko:K07706	ko02020,ko02024,map02020,map02024	M00495	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c_5
k141_4777_28	573061.Clocel_4255	1.28e-15	79.7	COG4512@1|root,COG4512@2|Bacteria,1VJBI@1239|Firmicutes,24GSH@186801|Clostridia,36I74@31979|Clostridiaceae	186801|Clostridia	KOT	May be involved in the proteolytic processing of a quorum sensing system signal molecule precursor	-	-	-	ko:K07813	ko02020,ko02024,map02020,map02024	-	-	-	ko00000,ko00001,ko01002	-	-	-	AgrB
k141_4777_29	386415.NT01CX_0259	1.39e-219	616.0	COG0001@1|root,COG0001@2|Bacteria,1TPNH@1239|Firmicutes,248II@186801|Clostridia,36FBX@31979|Clostridiaceae	186801|Clostridia	H	Aminotransferase	hemL	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
k141_4777_30	500633.CLOHIR_01522	5.13e-163	464.0	COG0113@1|root,COG0113@2|Bacteria,1TP09@1239|Firmicutes,2496V@186801|Clostridia,25QF1@186804|Peptostreptococcaceae	186801|Clostridia	H	Belongs to the ALAD family	hemB	-	4.2.1.24	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00036	RC00918,RC01781	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ALAD
k141_4777_31	386415.NT01CX_0261	1.29e-194	558.0	COG0007@1|root,COG1587@1|root,COG0007@2|Bacteria,COG1587@2|Bacteria,1TQNH@1239|Firmicutes,2487I@186801|Clostridia,36DBR@31979|Clostridiaceae	186801|Clostridia	H	Belongs to the precorrin methyltransferase family	cobA	-	1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.4	ko:K02302,ko:K02303,ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03165,R03194,R03947	RC00003,RC00871,RC01012,RC01034,RC01861	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS15755	HEM4,Porphobil_deam,Porphobil_deamC,TP_methylase
k141_4777_32	1391646.AVSU01000047_gene1599	6.71e-107	320.0	COG0181@1|root,COG0181@2|Bacteria,1TPFQ@1239|Firmicutes,2494Z@186801|Clostridia,25QEM@186804|Peptostreptococcaceae	186801|Clostridia	H	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps	hemC	-	2.5.1.61	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084	RC02317	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS15760	Porphobil_deam,Porphobil_deamC
k141_4777_33	888055.HMPREF9015_02127	4.22e-27	108.0	COG1648@1|root,COG1648@2|Bacteria,37A4S@32066|Fusobacteria	32066|Fusobacteria	H	Siroheme synthase domain protein	-	-	1.3.1.76,4.99.1.4	ko:K02304	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03947	RC01012,RC01034	ko00000,ko00001,ko00002,ko01000	-	-	-	NAD_binding_7
k141_4777_34	1347392.CCEZ01000019_gene967	3.99e-143	421.0	COG0373@1|root,COG0373@2|Bacteria,1TQN9@1239|Firmicutes,2496M@186801|Clostridia,36EQI@31979|Clostridiaceae	186801|Clostridia	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,GlutR_dimer,Shikimate_DH
k141_4777_35	1219626.HMPREF1639_05650	1.41e-62	203.0	COG2099@1|root,COG2099@2|Bacteria,1UHWY@1239|Firmicutes,24GIQ@186801|Clostridia,25QQ6@186804|Peptostreptococcaceae	186801|Clostridia	H	reductase	cobK	-	1.3.1.106,1.3.1.54	ko:K05895	ko00860,ko01100,map00860,map01100	-	R05150,R05812	RC01280	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS15690	CbiJ
k141_4777_36	500633.CLOHIR_00706	3.44e-119	346.0	COG1010@1|root,COG1010@2|Bacteria,1TPJ7@1239|Firmicutes,247QS@186801|Clostridia,25QEW@186804|Peptostreptococcaceae	186801|Clostridia	H	precorrin-3B C17-methyltransferase	cobJ	-	2.1.1.131,2.1.1.272	ko:K05934,ko:K21479	ko00860,ko01100,map00860,map01100	-	R05180,R05809,R11580	RC00003,RC01293,RC03471,RC03479	ko00000,ko00001,ko01000	-	-	-	TP_methylase
k141_4777_37	656519.Halsa_2195	4.98e-13	79.0	COG2073@1|root,COG2073@2|Bacteria,1TPYM@1239|Firmicutes,247JW@186801|Clostridia,3WBC2@53433|Halanaerobiales	186801|Clostridia	H	PFAM cobalamin (vitamin B12) biosynthesis CbiG protein	cbiG	-	3.7.1.12	ko:K02189	ko00860,ko01100,map00860,map01100	-	R07772	RC01545,RC02097	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS15705	CbiG_C,CbiG_N,CbiG_mid
k141_4777_38	1301100.HG529436_gene6551	2.82e-135	388.0	COG2875@1|root,COG2875@2|Bacteria,1TP6J@1239|Firmicutes,248IZ@186801|Clostridia,36DW3@31979|Clostridiaceae	186801|Clostridia	H	Precorrin-4 C(11)-methyltransferase	cobM	-	2.1.1.133,2.1.1.271	ko:K05936	ko00860,ko01100,map00860,map01100	-	R05181,R05810	RC00003,RC01294,RC02049	ko00000,ko00001,ko01000	-	-	-	TP_methylase
k141_4777_39	1301100.HG529436_gene6546	6.87e-99	295.0	COG2243@1|root,COG2243@2|Bacteria,1TP87@1239|Firmicutes,249DM@186801|Clostridia,36DZI@31979|Clostridiaceae	186801|Clostridia	H	Precorrin-2 C(20)-methyltransferase	cobI	-	2.1.1.130,2.1.1.151	ko:K03394	ko00860,ko01100,map00860,map01100	-	R03948,R05808	RC00003,RC01035,RC01662	ko00000,ko00001,ko01000	-	-	-	TP_methylase
k141_4777_40	272563.CD630_34270	3.96e-50	167.0	COG2242@1|root,COG2242@2|Bacteria,1TS3H@1239|Firmicutes,2483G@186801|Clostridia,25RAJ@186804|Peptostreptococcaceae	186801|Clostridia	H	Putative methyltransferase	cbiT	-	2.1.1.132,2.1.1.196	ko:K00595,ko:K02191	ko00860,ko01100,map00860,map01100	-	R05149,R05813,R07774	RC00003,RC01279,RC02052,RC02054	ko00000,ko00001,ko01000	-	-	-	CbiJ,Cons_hypoth95,MTS,Met_10,Methyltransf_31,Methyltransf_4,PCMT,TP_methylase
k141_4777_41	1151292.QEW_4050	1.83e-73	228.0	COG2241@1|root,COG2241@2|Bacteria,1V832@1239|Firmicutes,24JES@186801|Clostridia,25QJX@186804|Peptostreptococcaceae	186801|Clostridia	H	Precorrin-6y C5,15-methyltransferase (Decarboxylating)	cbiE	-	2.1.1.132,2.1.1.289	ko:K00595,ko:K03399	ko00860,ko01100,map00860,map01100	-	R05149,R05813,R07775	RC00003,RC01279,RC02052,RC02053	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS15725	TP_methylase
k141_4777_42	1408823.AXUS01000010_gene1896	1.36e-131	389.0	COG1903@1|root,COG1903@2|Bacteria,1TQ3M@1239|Firmicutes,248AK@186801|Clostridia,25QCM@186804|Peptostreptococcaceae	186801|Clostridia	H	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A	cbiD	-	2.1.1.195	ko:K02188	ko00860,ko01100,map00860,map01100	-	R07773	RC00003,RC02051	ko00000,ko00001,ko01000	-	-	-	CbiD
k141_4777_43	1151292.QEW_4052	4.19e-89	268.0	COG2082@1|root,COG2082@2|Bacteria,1V1SX@1239|Firmicutes,24B9Z@186801|Clostridia,25R69@186804|Peptostreptococcaceae	186801|Clostridia	H	Precorrin-8X methylmutase	cobH	-	5.4.99.60,5.4.99.61	ko:K06042	ko00860,ko01100,map00860,map01100	-	R05177,R05814	RC01292,RC01980	ko00000,ko00001,ko01000	-	-	-	CbiC
k141_4777_44	555079.Toce_1423	3.6e-37	141.0	COG4542@1|root,COG4542@2|Bacteria,1TSJB@1239|Firmicutes,24I5S@186801|Clostridia,42GB5@68295|Thermoanaerobacterales	186801|Clostridia	Q	COGs COG4542 Protein involved in propanediol utilization and related protein (includes coumermycin biosynthetic protein)	pduX	-	2.7.1.177	ko:K16651	ko00860,map00860	-	R06531	RC00002,RC00428	ko00000,ko00001,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
k141_4777_45	272563.CD630_34320	3.48e-112	337.0	COG0079@1|root,COG0079@2|Bacteria,1TP5D@1239|Firmicutes,248Q0@186801|Clostridia,25R5H@186804|Peptostreptococcaceae	186801|Clostridia	E	Aminotransferase class I and II	cobD2	-	4.1.1.81	ko:K04720	ko00860,map00860	-	R06530	RC00517	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS15770	Aminotran_1_2
k141_4777_47	1211817.CCAT010000044_gene3350	4.14e-06	54.3	COG1664@1|root,COG1664@2|Bacteria,1V6E6@1239|Firmicutes,24E2Y@186801|Clostridia,36GS1@31979|Clostridiaceae	186801|Clostridia	M	COG1664 Integral membrane protein CcmA involved in cell shape determination	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
k141_4777_49	1157637.KB892155_gene7739	2.26e-08	61.2	COG2197@1|root,COG2197@2|Bacteria,2GKBX@201174|Actinobacteria	201174|Actinobacteria	T	response regulator, receiver	-	-	-	ko:K02479	-	-	-	-	ko00000,ko02022	-	-	-	GerE,Response_reg
k141_4777_50	1408823.AXUS01000010_gene1892	1.3e-129	379.0	COG1270@1|root,COG1270@2|Bacteria,1TQ3X@1239|Firmicutes,247PR@186801|Clostridia,25QMF@186804|Peptostreptococcaceae	186801|Clostridia	H	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group	cobD	-	6.3.1.10	ko:K02227	ko00860,ko01100,map00860,map01100	M00122	R06529,R07302	RC00090,RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	CobD_Cbib
k141_4777_51	1476973.JMMB01000007_gene503	2.57e-187	536.0	COG1797@1|root,COG1797@2|Bacteria,1TNY2@1239|Firmicutes,247PU@186801|Clostridia,25QME@186804|Peptostreptococcaceae	186801|Clostridia	H	Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source	cbiA	-	6.3.5.11,6.3.5.9	ko:K02224	ko00860,ko01100,ko01120,map00860,map01100,map01120	-	R05224,R05815	RC00010,RC01301	ko00000,ko00001,ko01000	-	-	-	AAA_26,CbiA,GATase_3
k141_4777_54	1304284.L21TH_2057	1.21e-232	669.0	COG0849@1|root,COG0849@2|Bacteria,1TP1Z@1239|Firmicutes,249Y7@186801|Clostridia,36DWK@31979|Clostridiaceae	186801|Clostridia	D	cell division protein FtsA	ftsA	-	-	-	-	-	-	-	-	-	-	-	FtsA,MreB_Mbl
k141_4777_55	1219626.HMPREF1639_00800	3.97e-55	193.0	2DKA9@1|root,32UEQ@2|Bacteria,1VE7Y@1239|Firmicutes,24KB2@186801|Clostridia,25R3C@186804|Peptostreptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_4777_56	1476973.JMMB01000007_gene490	3.97e-111	326.0	COG0560@1|root,COG0560@2|Bacteria,1UYZ6@1239|Firmicutes,24AC7@186801|Clostridia,25QBY@186804|Peptostreptococcaceae	186801|Clostridia	E	HAD hydrolase, family IB	serB	-	-	-	-	-	-	-	-	-	-	-	HAD
k141_4777_57	985255.APHJ01000023_gene2674	9.11e-59	224.0	COG0642@1|root,COG2202@1|root,COG0642@2|Bacteria,COG2202@2|Bacteria,COG2205@2|Bacteria,4NDXU@976|Bacteroidetes,1HY32@117743|Flavobacteriia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,Hpt,PAS_3,PAS_9,Response_reg
k141_4777_58	743719.PaelaDRAFT_1110	2.64e-10	68.9	COG0715@1|root,COG0715@2|Bacteria,1V86M@1239|Firmicutes,4I6K6@91061|Bacilli,26TFH@186822|Paenibacillaceae	91061|Bacilli	P	Nitrate ABC transporter substrate-binding protein	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1
k141_4777_59	877424.ATWC01000019_gene1022	4.11e-44	164.0	COG2206@1|root,COG2206@2|Bacteria,1TR95@1239|Firmicutes,25AZS@186801|Clostridia,27K6D@186928|unclassified Lachnospiraceae	186801|Clostridia	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	HD,HD_5
k141_4777_60	1304284.L21TH_1331	2.32e-61	199.0	COG1285@1|root,COG1285@2|Bacteria,1V409@1239|Firmicutes,249SQ@186801|Clostridia,36EYH@31979|Clostridiaceae	186801|Clostridia	S	MgtC SapB transporter	-	-	-	ko:K07507	-	-	-	-	ko00000,ko02000	9.B.20	-	-	MgtC
k141_4777_61	981383.AEWH01000020_gene2506	2.33e-38	143.0	2DC01@1|root,2ZC51@2|Bacteria,1V2FW@1239|Firmicutes,4HG69@91061|Bacilli	91061|Bacilli	S	TraX protein	-	-	-	-	-	-	-	-	-	-	-	-	TraX
k141_3766_1	1121405.dsmv_2723	4.37e-299	840.0	COG0070@1|root,COG0493@1|root,COG1145@1|root,COG0070@2|Bacteria,COG0493@2|Bacteria,COG1145@2|Bacteria,1PBEZ@1224|Proteobacteria,42NFW@68525|delta/epsilon subdivisions,2WIQE@28221|Deltaproteobacteria,2MJ3I@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM Pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_20,Fer4_7,GXGXG,Pyr_redox_2,Pyr_redox_3,ThiF
k141_5116_2	272123.Anacy_0200	9.03e-40	138.0	2DMQT@1|root,32T2H@2|Bacteria,1G73M@1117|Cyanobacteria,1HMZ8@1161|Nostocales	1117|Cyanobacteria	S	PFAM T4-like virus tail tube protein gp19	-	-	-	-	-	-	-	-	-	-	-	-	Phage_T4_gp19
k141_5116_3	136273.GY22_14550	2.05e-15	70.1	arCOG11411@1|root,33A8Q@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_5116_4	1200792.AKYF01000018_gene5793	2.35e-56	178.0	arCOG11412@1|root,31S84@2|Bacteria,1V6H1@1239|Firmicutes,4HJGG@91061|Bacilli,26XZS@186822|Paenibacillaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_5116_5	1007103.AFHW01000139_gene1426	7.41e-61	191.0	2DB76@1|root,2Z7JZ@2|Bacteria,1V5UY@1239|Firmicutes,4HI95@91061|Bacilli,26X82@186822|Paenibacillaceae	91061|Bacilli	S	T4-like virus tail tube protein gp19	-	-	-	-	-	-	-	-	-	-	-	-	Phage_T4_gp19
k141_5116_6	1007103.AFHW01000139_gene1425	1.04e-284	793.0	COG3497@1|root,COG3497@2|Bacteria,1TNY8@1239|Firmicutes,4HCQV@91061|Bacilli,26S6A@186822|Paenibacillaceae	91061|Bacilli	S	Phage tail sheath C-terminal domain	-	-	-	ko:K06907	-	-	-	-	ko00000	-	-	-	Phage_sheath_1,Phage_sheath_1C
k141_5116_7	1122915.AUGY01000083_gene4483	2.39e-62	194.0	2ANY6@1|root,31DZ3@2|Bacteria,1VB43@1239|Firmicutes,4IQ37@91061|Bacilli,26XI8@186822|Paenibacillaceae	91061|Bacilli	S	Domain of unknown function (DUF4280)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4280
k141_5116_10	1122917.KB899681_gene370	9.45e-60	229.0	COG2114@1|root,COG5000@1|root,COG2114@2|Bacteria,COG5000@2|Bacteria,1V1JU@1239|Firmicutes,4HFW5@91061|Bacilli,26UQX@186822|Paenibacillaceae	91061|Bacilli	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc
k141_1735_1	1499680.CCFE01000030_gene3636	9.18e-15	74.7	COG4607@1|root,COG4607@2|Bacteria,1UXCZ@1239|Firmicutes,4HAMP@91061|Bacilli,1ZB26@1386|Bacillus	91061|Bacilli	P	COG4607 ABC-type enterochelin transport system, periplasmic component	yclQ	GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	iYO844.BSU03830	Peripla_BP_2
k141_1735_2	945543.VIBR0546_06057	2.44e-90	274.0	COG4606@1|root,COG4606@2|Bacteria,1MVSV@1224|Proteobacteria,1RQCK@1236|Gammaproteobacteria,1XTVI@135623|Vibrionales	135623|Vibrionales	P	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily	vctD	-	-	ko:K02015	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	FecCD
k141_2054_1	888743.HMPREF9141_1042	5.32e-36	134.0	COG1285@1|root,COG1285@2|Bacteria,4NM47@976|Bacteroidetes,2FP38@200643|Bacteroidia	976|Bacteroidetes	S	Mg2 transporter-C family protein	-	-	-	ko:K07507	-	-	-	-	ko00000,ko02000	9.B.20	-	-	MgtC
k141_2746_1	1120953.AUBH01000001_gene803	4.21e-31	123.0	COG1946@1|root,COG1946@2|Bacteria,1NAQM@1224|Proteobacteria,1RR0K@1236|Gammaproteobacteria,4645G@72275|Alteromonadaceae	1236|Gammaproteobacteria	I	acyl-CoA thioesterase	-	-	3.1.2.20	ko:K01073	-	-	-	-	ko00000,ko01000	-	-	-	4HBT_3
k141_2746_2	1232437.KL662020_gene658	6.78e-288	803.0	COG0038@1|root,COG0517@1|root,COG0038@2|Bacteria,COG0517@2|Bacteria,1MV4K@1224|Proteobacteria,42N93@68525|delta/epsilon subdivisions,2WJ9N@28221|Deltaproteobacteria,2MHX8@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Voltage gated chloride channel	-	-	-	ko:K03281	-	-	-	-	ko00000	2.A.49	-	-	CBS,TrkA_C,Voltage_CLC
k141_2746_3	96561.Dole_0588	3.32e-142	416.0	COG0436@1|root,COG0436@2|Bacteria,1QW10@1224|Proteobacteria,42MQA@68525|delta/epsilon subdivisions,2WJDK@28221|Deltaproteobacteria,2MJ7D@213118|Desulfobacterales	28221|Deltaproteobacteria	E	PFAM aminotransferase class I and II	bamJ	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
k141_722_1	290398.Csal_0011	7.77e-10	58.5	COG0463@1|root,COG0463@2|Bacteria,1RE4C@1224|Proteobacteria,1SJQD@1236|Gammaproteobacteria,1XR8Y@135619|Oceanospirillales	135619|Oceanospirillales	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
k141_722_2	1304885.AUEY01000010_gene1660	1.18e-168	489.0	COG0277@1|root,COG0277@2|Bacteria,1MU6Y@1224|Proteobacteria,42M0V@68525|delta/epsilon subdivisions,2WIQ1@28221|Deltaproteobacteria,2MI3F@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM FAD linked oxidase domain protein	larD	-	1.1.3.15	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001,ko01000	-	-	iAF987.Gmet_3245	FAD-oxidase_C,FAD_binding_4
k141_722_3	177437.HRM2_18560	2.74e-132	396.0	COG0593@1|root,COG0593@2|Bacteria,1MU5H@1224|Proteobacteria,42MA0@68525|delta/epsilon subdivisions,2WJAT@28221|Deltaproteobacteria,2MHNX@213118|Desulfobacterales	28221|Deltaproteobacteria	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	-	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
k141_58_1	999541.bgla_2g27990	2.15e-30	121.0	COG0145@1|root,COG0146@1|root,COG0145@2|Bacteria,COG0146@2|Bacteria,1MU2Y@1224|Proteobacteria,2VJUZ@28216|Betaproteobacteria,1K22A@119060|Burkholderiaceae	28216|Betaproteobacteria	EQ	5-oxoprolinase	-	-	3.5.2.14,3.5.2.9	ko:K01469,ko:K01473	ko00330,ko00480,ko01100,map00330,map00480,map01100	-	R00251,R03187	RC00553,RC00632	ko00000,ko00001,ko01000	-	-	-	Hydant_A_N,Hydantoinase_A,Hydantoinase_B
k141_58_2	1408473.JHXO01000009_gene3314	4.67e-155	452.0	COG1102@1|root,COG2364@1|root,COG1102@2|Bacteria,COG2364@2|Bacteria,4NMT3@976|Bacteroidetes,2G3EX@200643|Bacteroidia	976|Bacteroidetes	F	Cytidylate kinase-like family	-	-	-	-	-	-	-	-	-	-	-	-	Cytidylate_kin2
k141_373_1	1348635.BBJY01000013_gene1092	4.82e-155	441.0	2E4I1@1|root,32ZD4@2|Bacteria,1NUSC@1224|Proteobacteria,1SNB4@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_373_2	1517681.HW45_28250	4.61e-178	497.0	2AVJX@1|root,31MCM@2|Bacteria,1QJ7F@1224|Proteobacteria,1TH57@1236|Gammaproteobacteria,1Y05V@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_373_4	1051985.l11_00200	3.61e-150	439.0	COG0846@1|root,COG0846@2|Bacteria,1R5V1@1224|Proteobacteria	1224|Proteobacteria	K	SIR2-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SIR2_2
k141_1736_1	485916.Dtox_2675	2.16e-165	529.0	COG1020@1|root,COG1020@2|Bacteria,1TPTH@1239|Firmicutes,2490U@186801|Clostridia,260Y0@186807|Peptococcaceae	186801|Clostridia	Q	Belongs to the ATP-dependent AMP-binding enzyme family	-	-	-	ko:K04784	ko01053,map01053	-	-	-	ko00000,ko00001,ko01004,ko01008	-	-	-	AMP-binding,AMP-binding_C,Condensation,Methyltransf_12,NAD_binding_4,PP-binding
k141_2055_2	936136.ARRT01000002_gene572	0.00024	52.0	COG0745@1|root,COG0784@1|root,COG0840@1|root,COG1511@1|root,COG2203@1|root,COG4251@1|root,COG0745@2|Bacteria,COG0784@2|Bacteria,COG0840@2|Bacteria,COG1511@2|Bacteria,COG2203@2|Bacteria,COG4251@2|Bacteria,1NC9X@1224|Proteobacteria,2TW1J@28211|Alphaproteobacteria,4B7HQ@82115|Rhizobiaceae	28211|Alphaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HAMP,HATPase_c,HisKA,PAS_7,Response_reg
k141_60_1	1116375.VEJY3_21711	3.42e-145	418.0	COG1454@1|root,COG1454@2|Bacteria,1MVPH@1224|Proteobacteria,1RMVU@1236|Gammaproteobacteria,1XZTY@135623|Vibrionales	135623|Vibrionales	C	alcohol dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Fe-ADH
k141_4436_2	573061.Clocel_1182	1.84e-08	62.8	COG4733@1|root,COG5492@1|root,COG4733@2|Bacteria,COG5492@2|Bacteria,1VJUU@1239|Firmicutes,24FQ2@186801|Clostridia,36H9Q@31979|Clostridiaceae	186801|Clostridia	N	antibiotic catabolic process	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,DUF11,DUF5057
k141_4436_3	748727.CLJU_c31480	1.01e-31	135.0	COG5492@1|root,COG5492@2|Bacteria,1W2KG@1239|Firmicutes,24FQ5@186801|Clostridia,36E2B@31979|Clostridiaceae	186801|Clostridia	N	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_4436_4	1410653.JHVC01000032_gene1037	1.46e-72	239.0	COG5492@1|root,COG5492@2|Bacteria,1W2KG@1239|Firmicutes,24FQ5@186801|Clostridia,36E2B@31979|Clostridiaceae	186801|Clostridia	N	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_4436_5	1410653.JHVC01000032_gene1037	1.77e-47	178.0	COG5492@1|root,COG5492@2|Bacteria,1W2KG@1239|Firmicutes,24FQ5@186801|Clostridia,36E2B@31979|Clostridiaceae	186801|Clostridia	N	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_4436_6	1415774.U728_2127	4.93e-88	269.0	COG1387@1|root,COG1387@2|Bacteria,1TRKS@1239|Firmicutes,249TM@186801|Clostridia,36FRF@31979|Clostridiaceae	186801|Clostridia	E	Histidinol phosphate phosphatase, HisJ family	-	-	3.1.3.15	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03013	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PHP
k141_4436_8	317025.Tcr_1143	1.3e-76	258.0	COG2199@1|root,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,1T3X6@1236|Gammaproteobacteria,462E3@72273|Thiotrichales	72273|Thiotrichales	T	Double sensory domain of two-component sensor kinase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,dCache_3
k141_4436_9	1121324.CLIT_5c01230	2.17e-198	566.0	COG1167@1|root,COG1167@2|Bacteria,1TPS5@1239|Firmicutes,248ZB@186801|Clostridia,25QSF@186804|Peptostreptococcaceae	186801|Clostridia	K	Alanine-glyoxylate amino-transferase	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2,GntR
k141_4436_10	913848.AELK01000061_gene2255	4.37e-06	46.6	COG4224@1|root,COG4224@2|Bacteria,1VEKJ@1239|Firmicutes,4HNIB@91061|Bacilli,3F87S@33958|Lactobacillaceae	91061|Bacilli	S	UPF0291 protein	ynzC	-	-	-	-	-	-	-	-	-	-	-	DUF896
k141_4436_11	1121324.CLIT_5c01250	3.89e-60	190.0	COG0835@1|root,COG0835@2|Bacteria,1V4HH@1239|Firmicutes,249QN@186801|Clostridia,25UF5@186804|Peptostreptococcaceae	186801|Clostridia	NT	Two component signalling adaptor domain	-	-	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
k141_4436_12	1121324.CLIT_5c01260	8.47e-141	412.0	COG4585@1|root,COG4585@2|Bacteria,1TQI3@1239|Firmicutes,249R9@186801|Clostridia,25SMP@186804|Peptostreptococcaceae	186801|Clostridia	T	Histidine kinase	degS	-	2.7.13.3	ko:K07777	ko02020,map02020	M00478	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DegS,HATPase_c,HisKA_3
k141_4436_13	1121324.CLIT_5c01270	9.08e-108	315.0	COG2197@1|root,COG2197@2|Bacteria,1TRXG@1239|Firmicutes,24FZX@186801|Clostridia,25TCI@186804|Peptostreptococcaceae	186801|Clostridia	K	helix_turn_helix, Lux Regulon	degU	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
k141_4436_14	1304284.L21TH_1105	8.8e-167	489.0	COG1315@1|root,COG1315@2|Bacteria,1TR7W@1239|Firmicutes,24D54@186801|Clostridia,36F9H@31979|Clostridiaceae	186801|Clostridia	L	Pfam:DUF342	-	-	-	ko:K09749	-	-	-	-	ko00000	-	-	-	FapA
k141_4436_15	1121324.CLIT_5c01290	1.28e-82	258.0	COG0583@1|root,COG0583@2|Bacteria,1TSNI@1239|Firmicutes,249QS@186801|Clostridia	186801|Clostridia	K	lysR substrate binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
k141_4436_16	1121324.CLIT_5c01300	1.22e-278	800.0	COG0744@1|root,COG0744@2|Bacteria,1TPM5@1239|Firmicutes,248A4@186801|Clostridia,25QIB@186804|Peptostreptococcaceae	186801|Clostridia	M	penicillin-binding protein	mrcB	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
k141_4436_17	1286171.EAL2_c09910	5.99e-189	538.0	COG2262@1|root,COG2262@2|Bacteria,1TNZB@1239|Firmicutes,248IU@186801|Clostridia,25V8Z@186806|Eubacteriaceae	186801|Clostridia	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
k141_4436_18	445973.CLOBAR_01217	1.87e-48	166.0	COG1413@1|root,COG1413@2|Bacteria,1V61C@1239|Firmicutes,24FZ1@186801|Clostridia,25REB@186804|Peptostreptococcaceae	186801|Clostridia	C	HEAT repeats	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,HEAT_PBS,HTH_40
k141_4436_19	386415.NT01CX_0729	6.2e-120	357.0	COG0075@1|root,COG0075@2|Bacteria,1TPS0@1239|Firmicutes,24919@186801|Clostridia,36E72@31979|Clostridiaceae	186801|Clostridia	E	Aminotransferase	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
k141_4436_20	1121289.JHVL01000002_gene2387	3.67e-114	348.0	COG0111@1|root,COG0111@2|Bacteria,1V410@1239|Firmicutes,248H9@186801|Clostridia,36DCU@31979|Clostridiaceae	186801|Clostridia	EH	D-isomer specific 2-hydroxyacid dehydrogenase	serA	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C,ACT
k141_4436_21	929506.CbC4_2451	2.9e-80	249.0	COG1082@1|root,COG1082@2|Bacteria,1V56C@1239|Firmicutes,24D55@186801|Clostridia,36I65@31979|Clostridiaceae	186801|Clostridia	L	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
k141_4436_22	1230342.CTM_18206	6.41e-144	423.0	COG1058@1|root,COG1546@1|root,COG1058@2|Bacteria,COG1546@2|Bacteria,1TQ1N@1239|Firmicutes,249WC@186801|Clostridia,36ERG@31979|Clostridiaceae	186801|Clostridia	S	Belongs to the CinA family	cinA	-	3.5.1.42	ko:K03742,ko:K03743	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA,MoCF_biosynth
k141_4436_23	545697.HMPREF0216_02161	5.3e-66	209.0	COG0494@1|root,COG0494@2|Bacteria,1V6SF@1239|Firmicutes,24HCG@186801|Clostridia,36IWP@31979|Clostridiaceae	186801|Clostridia	L	pfam nudix	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
k141_4436_24	1121324.CLIT_5c01400	3.36e-08	55.5	COG3339@1|root,COG3339@2|Bacteria,1VP28@1239|Firmicutes,24WC2@186801|Clostridia	186801|Clostridia	S	Protein of unknown function (DUF1232)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1232
k141_4436_25	1232447.BAHW02000009_gene287	5.16e-70	230.0	COG0079@1|root,COG0079@2|Bacteria,1TP5D@1239|Firmicutes,248Q0@186801|Clostridia,26B3K@186813|unclassified Clostridiales	186801|Clostridia	E	Aminotransferase class I and II	hisC	-	4.1.1.81	ko:K04720	ko00860,map00860	-	R06530	RC00517	ko00000,ko00001,ko01000	-	-	-	Aminotran_1_2
k141_4436_26	1511.CLOST_1919	2.72e-73	224.0	COG0634@1|root,COG0634@2|Bacteria,1V1C9@1239|Firmicutes,24FR4@186801|Clostridia,25RGX@186804|Peptostreptococcaceae	186801|Clostridia	F	Phosphoribosyl transferase domain	hpt	-	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
k141_4436_27	1476973.JMMB01000007_gene810	8.71e-156	468.0	COG2208@1|root,COG2208@2|Bacteria,1TQY5@1239|Firmicutes,24FPA@186801|Clostridia,25QW1@186804|Peptostreptococcaceae	186801|Clostridia	T	Stage II sporulation protein E	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	GAF_2,SpoIIE
k141_4436_28	1151292.QEW_3228	7.14e-58	187.0	COG0655@1|root,COG0655@2|Bacteria,1V26K@1239|Firmicutes,24IAS@186801|Clostridia,25RCH@186804|Peptostreptococcaceae	186801|Clostridia	S	NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
k141_4436_29	1511.CLOST_1915	2.47e-96	284.0	COG4869@1|root,COG4869@2|Bacteria,1V242@1239|Firmicutes,24816@186801|Clostridia,25S2P@186804|Peptostreptococcaceae	186801|Clostridia	Q	Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate	pduL	-	2.3.1.8	ko:K15024	ko00430,ko00620,ko00640,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00720,map01100,map01120,map01200	M00579	R00230,R00921	RC00004,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000	-	-	-	Cob_adeno_trans,PTAC
k141_4436_30	1121324.CLIT_11c00240	1.38e-190	551.0	COG1227@1|root,COG1227@2|Bacteria,1TPH6@1239|Firmicutes,248RQ@186801|Clostridia,25R22@186804|Peptostreptococcaceae	186801|Clostridia	C	DHHA2	ppaC	-	3.6.1.1	ko:K15986	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	CBS,DHH,DHHA2,DRTGG
k141_4436_31	596315.HMPREF0634_1600	2.29e-180	512.0	COG3842@1|root,COG3842@2|Bacteria,1TP2M@1239|Firmicutes,247JR@186801|Clostridia,25QWM@186804|Peptostreptococcaceae	186801|Clostridia	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K10112	ko02010,map02010	M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1	-	-	ABC_tran,TOBE_2
k141_4436_32	1476973.JMMB01000007_gene1186	1.76e-22	100.0	COG2508@1|root,COG2508@2|Bacteria,1UESS@1239|Firmicutes,25JS8@186801|Clostridia,25TC5@186804|Peptostreptococcaceae	186801|Clostridia	QT	PucR C-terminal helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_30
k141_4436_33	1380408.AVGH01000024_gene1641	3.86e-72	225.0	COG0637@1|root,COG0637@2|Bacteria,1UY8N@1239|Firmicutes,4HFF9@91061|Bacilli,21WUJ@150247|Anoxybacillus	91061|Bacilli	S	haloacid dehalogenase-like hydrolase	pgmB	-	5.4.2.6	ko:K01838	ko00500,map00500	-	R02728,R11310	RC00408	ko00000,ko00001,ko01000	-	-	-	HAD_2
k141_4436_34	1123300.AUIN01000017_gene698	3.21e-45	162.0	COG2017@1|root,COG2017@2|Bacteria,1U26T@1239|Firmicutes,4HA4J@91061|Bacilli	91061|Bacilli	G	Aldose 1-epimerase	lacX	-	-	-	-	-	-	-	-	-	-	-	Aldose_epim
k141_4436_35	1274524.BSONL12_06428	7.19e-278	775.0	COG0366@1|root,COG0366@2|Bacteria,1TP53@1239|Firmicutes,4HA1G@91061|Bacilli,1ZASC@1386|Bacillus	91061|Bacilli	G	COG0366 Glycosidases	malL	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	3.2.1.10	ko:K01182	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00801,R01718,R01791,R06199	RC00028,RC00059,RC00077,RC00451	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,DUF3459,Malt_amylase_C
k141_4436_36	441769.ABFU01000013_gene2518	0.0	1007.0	COG1554@1|root,COG1554@2|Bacteria,1TQMB@1239|Firmicutes,4HAVB@91061|Bacilli,1ZBSM@1386|Bacillus	91061|Bacilli	G	Glycoside hydrolase, family 65	mapA	GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0016787,GO:0030312,GO:0044464,GO:0071944	2.4.1.8	ko:K00691	ko00500,ko01100,map00500,map01100	-	R01555	RC00049	ko00000,ko00001,ko01000	-	GH65	-	Glyco_hydro_65C,Glyco_hydro_65N,Glyco_hydro_65m
k141_87_2	1219065.VPR01S_07_01510	2.75e-133	395.0	COG3007@1|root,COG3007@2|Bacteria,1QJA8@1224|Proteobacteria,1RU33@1236|Gammaproteobacteria,1XTE7@135623|Vibrionales	135623|Vibrionales	I	Involved in the final reduction of the elongation cycle of fatty acid synthesis (FAS II). Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP)	fabV2	-	1.3.1.44,1.3.1.9	ko:K00209	ko00061,ko00650,ko01100,ko01120,ko01200,ko01212,map00061,map00650,map01100,map01120,map01200,map01212	M00083	R01171,R04429,R04724,R04955,R04958,R04961,R04966,R04969	RC00052,RC00076	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Eno-Rase_FAD_bd,Eno-Rase_NADH_b,Enoyl_reductase
k141_87_3	55601.VANGNB10_cII0745	1.38e-66	230.0	COG2199@1|root,COG2200@1|root,COG2203@1|root,COG2199@2|Bacteria,COG2200@2|Bacteria,COG2203@2|Bacteria,1RGKE@1224|Proteobacteria,1T1I8@1236|Gammaproteobacteria,1XUWZ@135623|Vibrionales	135623|Vibrionales	T	GGDEF family	-	-	3.1.4.52	ko:K20962	ko05111,map05111	-	-	-	ko00000,ko00001,ko01000	-	-	-	EAL,GAF,GAF_2,GGDEF
k141_4789_1	223926.28806147	8.74e-41	143.0	COG0390@1|root,COG0390@2|Bacteria,1MV2N@1224|Proteobacteria,1RSGA@1236|Gammaproteobacteria,1XT6E@135623|Vibrionales	135623|Vibrionales	S	transport system, permease component	-	-	-	ko:K02069	-	M00211	-	-	ko00000,ko00002,ko02000	9.B.25.1	-	-	UPF0014
k141_4789_2	345073.VC395_1334	1.28e-105	307.0	COG0558@1|root,COG0558@2|Bacteria,1RCZ7@1224|Proteobacteria,1S465@1236|Gammaproteobacteria,1XT7Y@135623|Vibrionales	135623|Vibrionales	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pgsA	-	2.7.8.5	ko:K00995	ko00564,ko01100,map00564,map01100	-	R01801	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
k141_4789_3	945543.VIBR0546_10809	0.0	967.0	COG0322@1|root,COG0322@2|Bacteria,1MV38@1224|Proteobacteria,1RNGV@1236|Gammaproteobacteria,1XT19@135623|Vibrionales	135623|Vibrionales	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009380,GO:0009381,GO:0009987,GO:0016787,GO:0016788,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1902494,GO:1905347,GO:1905348,GO:1990391	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH,HHH_5,UVR,UvrC_HhH_N
k141_4789_4	1348635.BBJY01000017_gene4158	5.22e-142	402.0	COG2197@1|root,COG2197@2|Bacteria,1MWGM@1224|Proteobacteria,1RQ1J@1236|Gammaproteobacteria,1XUFX@135623|Vibrionales	135623|Vibrionales	K	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	sirA	-	-	ko:K07689	ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111	M00475	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
k141_4789_5	1187848.AJYQ01000080_gene1283	7.33e-82	245.0	2DMP9@1|root,32SV1@2|Bacteria,1N17Y@1224|Proteobacteria,1S8UW@1236|Gammaproteobacteria,1XX8X@135623|Vibrionales	135623|Vibrionales	S	Protein of unknown function (DUF3015)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3015
k141_4789_6	870967.VIS19158_15609	2.88e-250	709.0	28J7E@1|root,2Z92U@2|Bacteria,1NAE1@1224|Proteobacteria,1RRQ0@1236|Gammaproteobacteria,1XUNQ@135623|Vibrionales	135623|Vibrionales	S	Domain of unknown function (DUF4105)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4105
k141_4789_7	672.VV93_v1c11490	0.0	990.0	COG0417@1|root,COG0417@2|Bacteria,1MVY9@1224|Proteobacteria,1RMQ1@1236|Gammaproteobacteria,1XTIT@135623|Vibrionales	135623|Vibrionales	L	COG0417 DNA polymerase elongation subunit (family B)	polB	-	2.7.7.7	ko:K02336	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_pol_B,DNA_pol_B_exo1
k141_4789_8	243277.VC_1210	1.14e-133	384.0	COG1708@1|root,COG1708@2|Bacteria,1RID1@1224|Proteobacteria,1S9KW@1236|Gammaproteobacteria,1XTT0@135623|Vibrionales	135623|Vibrionales	S	nucleotidyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_2
k141_3457_1	1499967.BAYZ01000097_gene4327	8.07e-76	240.0	COG1486@1|root,COG1486@2|Bacteria	2|Bacteria	G	melibiose metabolic process	-	-	3.2.1.22,3.2.1.86	ko:K01222,ko:K07406	ko00010,ko00052,ko00500,ko00561,ko00600,ko00603,map00010,map00052,map00500,map00561,map00600,map00603	-	R00839,R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05133,R05134,R05549,R05961,R06091	RC00049,RC00059,RC00171,RC00451,RC00714	ko00000,ko00001,ko01000	-	GT4	-	Glyco_hydro_4,Glyco_hydro_4C
k141_3769_1	330214.NIDE0346	4.54e-13	77.8	COG3016@1|root,COG3016@2|Bacteria	2|Bacteria	S	Haem-binding uptake, Tiki superfamily, ChaN	phuW	-	-	-	-	-	-	-	-	-	-	-	Cofac_haem_bdg,PDZ_2
k141_3769_2	522772.Dacet_0825	3.32e-150	458.0	COG1629@1|root,COG4771@2|Bacteria,2GGQ1@200930|Deferribacteres	200930|Deferribacteres	P	TonB-dependent Receptor Plug Domain	-	-	-	ko:K16087	-	-	-	-	ko00000,ko02000	1.B.14.2	-	-	Plug,TonB_dep_Rec
k141_3769_3	563192.HMPREF0179_03208	1.13e-158	464.0	COG0635@1|root,COG0635@2|Bacteria,1NTDN@1224|Proteobacteria,43BFD@68525|delta/epsilon subdivisions,2X6TR@28221|Deltaproteobacteria,2MER9@213115|Desulfovibrionales	28221|Deltaproteobacteria	H	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
k141_3769_4	933262.AXAM01000080_gene2303	4.06e-59	190.0	2B1J1@1|root,31U0A@2|Bacteria,1RFTW@1224|Proteobacteria,42SIK@68525|delta/epsilon subdivisions,2WPVN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Hypothetical bacterial integral membrane protein (Trep_Strep)	-	-	-	-	-	-	-	-	-	-	-	-	Trep_Strep
k141_3769_5	653733.Selin_2022	2.38e-64	208.0	COG0619@1|root,COG0619@2|Bacteria	2|Bacteria	P	transmembrane transporter activity	-	-	-	ko:K16785	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	CbiQ
k141_3769_6	653733.Selin_2021	1.24e-150	443.0	COG1122@1|root,COG1122@2|Bacteria	2|Bacteria	P	ATPase activity	-	-	-	ko:K16786,ko:K16787	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ABC_tran
k141_3458_1	28229.ND2E_0988	8.11e-16	75.1	COG5566@1|root,COG5566@2|Bacteria,1N0IH@1224|Proteobacteria,1SBYY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	transcription	-	-	-	-	-	-	-	-	-	-	-	-	Mor
k141_4455_1	439235.Dalk_1083	1.24e-62	207.0	COG0446@1|root,COG0446@2|Bacteria,1NR3M@1224|Proteobacteria,42N3G@68525|delta/epsilon subdivisions,2WIS9@28221|Deltaproteobacteria,2MI5A@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Pyr_redox_dim
k141_4455_2	933262.AXAM01000040_gene1224	6.96e-144	421.0	COG0501@1|root,COG0501@2|Bacteria,1MUXT@1224|Proteobacteria,42P1M@68525|delta/epsilon subdivisions,2WKJ2@28221|Deltaproteobacteria,2MJ05@213118|Desulfobacterales	28221|Deltaproteobacteria	O	CAAX prenyl protease N-terminal, five membrane helices	-	-	3.4.24.84	ko:K06013	ko00900,ko01130,map00900,map01130	-	R09845	RC00141	ko00000,ko00001,ko01000,ko01002,ko04147	-	-	-	Peptidase_M48,Peptidase_M48_N
k141_88_2	1216007.AOPM01000092_gene966	2.9e-20	89.0	COG3324@1|root,COG3324@2|Bacteria,1R81W@1224|Proteobacteria,1RYXR@1236|Gammaproteobacteria,2Q1G4@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	S	enzyme related to lactoylglutathione lyase	-	-	-	ko:K06996	-	-	-	-	ko00000	-	-	-	Glyoxalase
k141_4456_1	1121405.dsmv_1339	4.59e-157	473.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2WJVV@28221|Deltaproteobacteria,2MI7E@213118|Desulfobacterales	28221|Deltaproteobacteria	V	Hydrophobe Amphiphile Efflux-1 (HAE1) Family	acrB	-	-	ko:K03296,ko:K18138	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
k141_89_1	1238450.VIBNISOn1_360037	3.38e-15	73.2	2C4GN@1|root,2ZHR0@2|Bacteria,1P917@1224|Proteobacteria,1STX2@1236|Gammaproteobacteria,1XY3H@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_3770_2	637905.SVI_0526	4.17e-135	401.0	COG4988@1|root,COG4988@2|Bacteria,1QU1N@1224|Proteobacteria,1RNPI@1236|Gammaproteobacteria,2Q9I6@267890|Shewanellaceae	1236|Gammaproteobacteria	V	PFAM ABC transporter transmembrane region	cydD	GO:0000101,GO:0003333,GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006857,GO:0006865,GO:0006869,GO:0008150,GO:0009987,GO:0010876,GO:0015399,GO:0015405,GO:0015711,GO:0015804,GO:0015833,GO:0015849,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019725,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0032973,GO:0032991,GO:0033036,GO:0033228,GO:0034040,GO:0034220,GO:0034635,GO:0034775,GO:0035443,GO:0035672,GO:0042592,GO:0042623,GO:0042626,GO:0042883,GO:0042886,GO:0042939,GO:0043190,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0045454,GO:0046942,GO:0050789,GO:0050794,GO:0051179,GO:0051181,GO:0051234,GO:0055085,GO:0065007,GO:0065008,GO:0071702,GO:0071705,GO:0071944,GO:0072337,GO:0072348,GO:0098533,GO:0098655,GO:0098656,GO:0098796,GO:0098797,GO:0140115,GO:1902494,GO:1902495,GO:1903712,GO:1903825,GO:1904949,GO:1905039,GO:1990351	-	ko:K16013	ko02010,map02010	-	-	-	ko00000,ko00001,ko02000	3.A.1.129	-	iEC042_1314.EC042_0979,iECUMN_1333.ECUMN_1082,iETEC_1333.ETEC_0955	ABC_membrane,ABC_tran
k141_4457_1	1121396.KB892935_gene3857	4.14e-112	329.0	COG4990@1|root,COG4990@2|Bacteria,1MVC4@1224|Proteobacteria,42QF6@68525|delta/epsilon subdivisions,2WM99@28221|Deltaproteobacteria,2MKVS@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Butirosin biosynthesis protein H, N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	BtrH_N,DUF4872
k141_4458_1	1304885.AUEY01000007_gene1363	2.52e-86	288.0	COG1924@1|root,COG3580@1|root,COG3581@1|root,COG1924@2|Bacteria,COG3580@2|Bacteria,COG3581@2|Bacteria,1PKG6@1224|Proteobacteria,42MY4@68525|delta/epsilon subdivisions,2WJFI@28221|Deltaproteobacteria,2MIP0@213118|Desulfobacterales	28221|Deltaproteobacteria	I	BadF BadG BcrA BcrD	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG,DUF2229
k141_2060_1	1173024.KI912149_gene5615	3.22e-22	101.0	COG1835@1|root,COG1835@2|Bacteria,1GGW4@1117|Cyanobacteria	1117|Cyanobacteria	I	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
k141_2060_2	349521.HCH_04692	1.62e-83	272.0	COG2244@1|root,COG2244@2|Bacteria,1PFDQ@1224|Proteobacteria,1RWEY@1236|Gammaproteobacteria,1XQ8M@135619|Oceanospirillales	135619|Oceanospirillales	S	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt_3
k141_2060_3	1385511.N783_07220	3.27e-22	106.0	COG0463@1|root,COG2327@1|root,COG0463@2|Bacteria,COG2327@2|Bacteria,1UXDJ@1239|Firmicutes,4I2J2@91061|Bacilli,2YBDC@289201|Pontibacillus	91061|Bacilli	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
k141_2060_4	376686.Fjoh_0343	2.38e-24	108.0	COG1215@1|root,COG1215@2|Bacteria,4NIMF@976|Bacteroidetes,1I09D@117743|Flavobacteriia,2P0JE@237|Flavobacterium	976|Bacteroidetes	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
k141_2060_5	1488328.JMCL01000010_gene115	1.18e-103	312.0	COG0463@1|root,COG0463@2|Bacteria,1N8QE@1224|Proteobacteria,1S882@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
k141_2060_6	504487.JCM19302_2486	4.04e-57	184.0	COG1045@1|root,COG1045@2|Bacteria,4NMY9@976|Bacteroidetes,1I1S6@117743|Flavobacteriia	976|Bacteroidetes	E	Bacterial transferase hexapeptide (six repeats)	-	-	2.3.1.30	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	M00021	R00586	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep
k141_2060_7	1488328.JMCL01000010_gene116	4.39e-84	271.0	COG3307@1|root,COG3307@2|Bacteria,1R5EX@1224|Proteobacteria,1S7G7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	O-Antigen ligase	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
k141_2060_8	983545.Glaag_3316	2.09e-135	398.0	COG0438@1|root,COG0438@2|Bacteria,1RKCN@1224|Proteobacteria,1S4CE@1236|Gammaproteobacteria,46BAR@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
k141_2060_9	349521.HCH_04683	1.53e-92	296.0	COG0438@1|root,COG1922@1|root,COG0438@2|Bacteria,COG1922@2|Bacteria,1N1HD@1224|Proteobacteria,1RP6P@1236|Gammaproteobacteria,1XMDY@135619|Oceanospirillales	135619|Oceanospirillales	M	Glycosyl transferase WecB/TagA/CpsF family	-	-	2.4.1.180	ko:K02852	-	-	-	-	ko00000,ko01000,ko01003	-	GT26	-	Glyco_tran_WecB
k141_2060_10	318167.Sfri_1375	5.82e-101	301.0	COG1922@1|root,COG1922@2|Bacteria,1N1HD@1224|Proteobacteria,1RP6P@1236|Gammaproteobacteria,2QAQA@267890|Shewanellaceae	1236|Gammaproteobacteria	M	TIGRFAM glycosyl transferase, WecB TagA CpsF family	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf,Glyco_tran_WecB
k141_2060_11	318167.Sfri_1374	5.48e-177	500.0	COG0451@1|root,COG0451@2|Bacteria,1MU7J@1224|Proteobacteria,1RPTA@1236|Gammaproteobacteria,2Q8KK@267890|Shewanellaceae	1236|Gammaproteobacteria	M	PFAM NAD-dependent epimerase dehydratase	lspL	-	5.1.3.25,5.1.3.6	ko:K08679,ko:K17947	ko00520,ko00523,ko01100,ko01130,map00520,map00523,map01100,map01130	-	R01385,R10279	RC00289	ko00000,ko00001,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
k141_2060_12	945550.VISI1226_10672	4.71e-250	718.0	COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,1MVI9@1224|Proteobacteria,1RNB0@1236|Gammaproteobacteria,1XTE5@135623|Vibrionales	135623|Vibrionales	D	protein involved in exopolysaccharide biosynthesis	-	-	-	ko:K16554	ko05111,map05111	-	-	-	ko00000,ko00001,ko02000	8.A.3.1	-	-	AAA_31,GNVR,Wzz
k141_2060_13	701176.VIBRN418_10268	4.04e-50	167.0	COG1596@1|root,COG1596@2|Bacteria,1MXYS@1224|Proteobacteria,1SC60@1236|Gammaproteobacteria,1Y2XB@135623|Vibrionales	135623|Vibrionales	M	COG1596 Periplasmic protein involved in polysaccharide export	-	-	-	ko:K20988	ko05111,map05111	-	-	-	ko00000,ko00001,ko02000	1.B.18	-	-	Poly_export,SLBB
k141_2060_14	1051646.VITU9109_01577	3.29e-168	489.0	COG2148@1|root,COG2148@2|Bacteria,1MV6W@1224|Proteobacteria,1RMMN@1236|Gammaproteobacteria,1XTWQ@135623|Vibrionales	135623|Vibrionales	M	COG2148 Sugar transferases involved in lipopolysaccharide synthesis	-	-	-	ko:K03606	ko05111,map05111	-	-	-	ko00000,ko00001	-	-	-	Bac_transf,CoA_binding_3
k141_2060_15	1191299.AJYX01000064_gene3557	7.03e-60	189.0	COG0454@1|root,COG0456@2|Bacteria,1RIE6@1224|Proteobacteria,1S9G0@1236|Gammaproteobacteria,1XXEY@135623|Vibrionales	135623|Vibrionales	K	This enzyme acetylates the N-terminal alanine of ribosomal protein S18	rimI	-	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1,Acetyltransf_10
k141_2060_17	675814.VIC_000788	6.76e-30	114.0	COG3153@1|root,COG3153@2|Bacteria,1RA42@1224|Proteobacteria,1S2G0@1236|Gammaproteobacteria,1XWYS@135623|Vibrionales	135623|Vibrionales	S	Acetyltransferase	yhbS	-	-	ko:K03824	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_1,Acetyltransf_7,Acetyltransf_9
k141_3539_14	1188252.AJYK01000033_gene1023	5.59e-89	286.0	COG0642@1|root,COG0642@2|Bacteria,1N6S8@1224|Proteobacteria,1RRCJ@1236|Gammaproteobacteria,1XV71@135623|Vibrionales	135623|Vibrionales	T	GHKL domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HATPase_c_5,HisKA
k141_3539_16	1042375.AFPL01000026_gene3667	7.06e-248	708.0	COG0840@1|root,COG3287@1|root,COG0840@2|Bacteria,COG3287@2|Bacteria,1MVUZ@1224|Proteobacteria,1RY7N@1236|Gammaproteobacteria,465QT@72275|Alteromonadaceae	1236|Gammaproteobacteria	NT	FIST N domain	-	-	-	-	-	-	-	-	-	-	-	-	FIST,FIST_C
k141_3539_17	675814.VIC_002325	8.3e-145	416.0	COG3409@1|root,COG3409@2|Bacteria,1RAYU@1224|Proteobacteria,1RX19@1236|Gammaproteobacteria,1XZPA@135623|Vibrionales	135623|Vibrionales	M	Peptidoglycan-binding	-	-	-	-	-	-	-	-	-	-	-	-	Muraidase
k141_3539_19	1238450.VIBNISOn1_1750005	8.74e-70	222.0	COG3675@1|root,COG3675@2|Bacteria,1PR4K@1224|Proteobacteria,1TJ23@1236|Gammaproteobacteria,1Y0C5@135623|Vibrionales	135623|Vibrionales	I	Lamin Tail Domain	-	-	-	-	-	-	-	-	-	-	-	-	LTD
k141_3539_20	675814.VIC_002319	1.28e-108	327.0	2DRW5@1|root,33DD3@2|Bacteria,1NHZJ@1224|Proteobacteria,1TIZX@1236|Gammaproteobacteria,1Y05M@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_3539_22	675814.VIC_002318	2.3e-41	141.0	2AXPU@1|root,31PQJ@2|Bacteria,1QMDT@1224|Proteobacteria,1TJNM@1236|Gammaproteobacteria,1Y1FX@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_3539_23	1238450.VIBNISOn1_1750013	2.94e-23	92.8	2BA0X@1|root,323EN@2|Bacteria,1QMA3@1224|Proteobacteria,1TJIB@1236|Gammaproteobacteria,1Y19Z@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_3539_25	675814.VIC_002314	1.59e-135	387.0	2AX44@1|root,31P2G@2|Bacteria,1QKRM@1224|Proteobacteria,1TIW7@1236|Gammaproteobacteria,1XZTV@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_3539_26	1238450.VIBNISOn1_1750016	8.5e-67	216.0	2AX8U@1|root,31P7S@2|Bacteria,1QKXJ@1224|Proteobacteria,1TJ3H@1236|Gammaproteobacteria,1Y0FJ@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_3539_29	717774.Marme_2668	1.24e-41	138.0	2CU57@1|root,333RB@2|Bacteria,1N95P@1224|Proteobacteria,1SZR2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_3539_30	675814.VIC_002301	6.61e-24	91.7	2AXY5@1|root,31PZF@2|Bacteria,1QMND@1224|Proteobacteria,1TJXX@1236|Gammaproteobacteria,1Y1U1@135623|Vibrionales	135623|Vibrionales	S	Killing trait	-	-	-	-	-	-	-	-	-	-	-	-	RebB
k141_3539_31	675814.VIC_002300	3.63e-37	127.0	2BI4W@1|root,30WUI@2|Bacteria,1PIJ4@1224|Proteobacteria,1TJHF@1236|Gammaproteobacteria,1Y18R@135623|Vibrionales	135623|Vibrionales	S	Killing trait	-	-	-	-	-	-	-	-	-	-	-	-	RebB
k141_1890_9	1121396.KB892901_gene2195	3.27e-177	501.0	COG0016@1|root,COG0016@2|Bacteria,1MVD7@1224|Proteobacteria,42MB0@68525|delta/epsilon subdivisions,2WJ42@28221|Deltaproteobacteria,2MI3B@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily	pheS	GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iAF987.Gmet_1415	Phe_tRNA-synt_N,tRNA-synt_2d
k141_1890_10	1232437.KL661965_gene3234	2.44e-248	719.0	COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria,1MWKS@1224|Proteobacteria,42M1G@68525|delta/epsilon subdivisions,2WJ7V@28221|Deltaproteobacteria,2MI13@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily	pheT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
k141_1890_11	717605.Theco_2061	4.4e-23	96.3	COG0779@1|root,COG0779@2|Bacteria,1V6KT@1239|Firmicutes,4HH88@91061|Bacilli,26R8B@186822|Paenibacillaceae	91061|Bacilli	S	Required for maturation of 30S ribosomal subunits	rimP	GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576	-	ko:K09748	-	-	-	-	ko00000,ko03009	-	-	-	DUF150,DUF150_C
k141_1890_12	879212.DespoDRAFT_00762	1.42e-151	439.0	COG0195@1|root,COG0195@2|Bacteria,1MWT7@1224|Proteobacteria,42MUW@68525|delta/epsilon subdivisions,2WIXI@28221|Deltaproteobacteria,2MHW6@213118|Desulfobacterales	28221|Deltaproteobacteria	K	Participates in both transcription termination and antitermination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	HHH_5,KH_5,NusA_N,S1
k141_240_1	697281.Mahau_2653	2.95e-97	317.0	COG4231@1|root,COG4231@2|Bacteria,1TNY3@1239|Firmicutes,24AKB@186801|Clostridia,42F0D@68295|Thermoanaerobacterales	186801|Clostridia	C	Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates	-	-	1.2.7.8	ko:K00179	-	-	-	-	br01601,ko00000,ko01000	-	-	-	Fer4,POR_N,TPP_enzyme_C
k141_1492_1	1121324.CLIT_17c00090	0.0	1760.0	COG0674@1|root,COG1013@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,1TQJ2@1239|Firmicutes,248FW@186801|Clostridia,25QC0@186804|Peptostreptococcaceae	186801|Clostridia	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	nifJ	-	1.2.7.1	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00173,M00307	R01196,R10866	RC00004,RC02742	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	EKR,Fer4_16,Fer4_7,PFOR_II,POR,POR_N,TPP_enzyme_C
k141_1492_9	865861.AZSU01000001_gene413	2.84e-133	389.0	COG0491@1|root,COG0491@2|Bacteria,1TQPX@1239|Firmicutes,24BDQ@186801|Clostridia,36G47@31979|Clostridiaceae	186801|Clostridia	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
k141_1891_1	411474.COPEUT_00085	1.73e-08	62.0	COG0642@1|root,COG0784@1|root,COG3452@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,COG3452@2|Bacteria,1TQMV@1239|Firmicutes,247SE@186801|Clostridia	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,HATPase_c,HisKA,Response_reg
k141_2189_1	272560.BPSS1423	2.24e-30	120.0	COG2113@1|root,COG2113@2|Bacteria,1MVIG@1224|Proteobacteria,2VNP5@28216|Betaproteobacteria,1K4J0@119060|Burkholderiaceae	28216|Betaproteobacteria	E	choline ABC transporter, periplasmic binding	-	-	-	ko:K02002	ko02010,map02010	M00208	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	OpuAC
k141_242_1	1121396.KB893080_gene895	2.98e-154	469.0	COG0500@1|root,COG0535@1|root,COG0535@2|Bacteria,COG2226@2|Bacteria,1MVXN@1224|Proteobacteria,42N5I@68525|delta/epsilon subdivisions,2WM5T@28221|Deltaproteobacteria,2MIA6@213118|Desulfobacterales	28221|Deltaproteobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	2.1.1.137	ko:K07755	-	-	-	-	ko00000,ko01000	-	-	-	Fer4_12,Fer4_14,Methyltransf_31,Radical_SAM
k141_2190_1	1121396.KB893054_gene2405	5.26e-16	76.6	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MIZ@68525|delta/epsilon subdivisions,2WIUX@28221|Deltaproteobacteria,2MJ42@213118|Desulfobacterales	28221|Deltaproteobacteria	T	PFAM ATP-binding region ATPase domain protein	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	CHASE5,HAMP,HATPase_c,HisKA,dCache_1,dCache_2
k141_2190_2	1121396.KB893054_gene2404	1.26e-75	229.0	COG2204@1|root,COG2204@2|Bacteria,1MYQ1@1224|Proteobacteria,42TBS@68525|delta/epsilon subdivisions,2WNQA@28221|Deltaproteobacteria,2MJTT@213118|Desulfobacterales	28221|Deltaproteobacteria	T	PFAM response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
k141_4929_2	55601.VANGNB10_cI1100c	2.86e-182	513.0	COG0189@1|root,COG0189@2|Bacteria,1MVDU@1224|Proteobacteria,1RR7D@1236|Gammaproteobacteria,1XV35@135623|Vibrionales	135623|Vibrionales	HJ	COG0189 Glutathione synthase Ribosomal protein S6 modification enzyme (glutaminyl transferase)	PA1766	-	-	-	-	-	-	-	-	-	-	-	ATPgrasp_ST
k141_4929_3	1123517.JOMR01000001_gene421	5.24e-26	119.0	COG2199@1|root,COG2203@1|root,COG2203@2|Bacteria,COG3706@2|Bacteria,1MXAW@1224|Proteobacteria,1RZ41@1236|Gammaproteobacteria,462HX@72273|Thiotrichales	72273|Thiotrichales	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
k141_3221_2	675814.VIC_001229	7.08e-258	752.0	COG0507@1|root,COG0550@1|root,COG1112@1|root,COG0507@2|Bacteria,COG0550@2|Bacteria,COG1112@2|Bacteria,1N8SW@1224|Proteobacteria,1SN1Z@1236|Gammaproteobacteria,1XXPT@135623|Vibrionales	135623|Vibrionales	L	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_11,AAA_12,PLDc_2,Toprim
k141_1229_1	55601.VANGNB10_cII0434	4.53e-101	300.0	2E9FB@1|root,333NN@2|Bacteria,1NEQE@1224|Proteobacteria,1SEY3@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_1229_3	55601.VANGNB10_cII0433	1.68e-92	277.0	COG0433@1|root,COG0433@2|Bacteria,1N2WU@1224|Proteobacteria,1SPVK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	COG0433 Predicted ATPase	-	-	-	ko:K06915	-	-	-	-	ko00000	-	-	-	-
k141_1229_8	1136163.M565_ctg5P0651	4.78e-147	435.0	28M2E@1|root,2ZAGW@2|Bacteria,1R97D@1224|Proteobacteria,1RURR@1236|Gammaproteobacteria,1XVXB@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_1494_1	857087.Metme_3225	1.41e-27	102.0	COG1396@1|root,COG1396@2|Bacteria,1RJ0X@1224|Proteobacteria,1S7WA@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
k141_1494_2	857087.Metme_3226	1.13e-108	326.0	COG3344@1|root,COG3344@2|Bacteria,1RIDA@1224|Proteobacteria,1T1D7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	reverse transcriptase	-	-	2.7.7.49	ko:K00986	-	-	-	-	ko00000,ko01000	-	-	-	RVT_1
k141_1494_3	1217658.F987_03392	2e-32	126.0	2AEJW@1|root,314FG@2|Bacteria,1NBZ3@1224|Proteobacteria,1SQSR@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_5188_2	261292.Nit79A3_1625	6.83e-67	223.0	COG3719@1|root,COG3719@2|Bacteria,1NRPM@1224|Proteobacteria,2WD2R@28216|Betaproteobacteria,373Y1@32003|Nitrosomonadales	28216|Betaproteobacteria	J	Belongs to the RNase T2 family	-	-	3.1.27.1	ko:K01166	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Ribonuclease_T2
k141_5188_3	1348635.BBJY01000010_gene1332	4.84e-71	219.0	COG3658@1|root,COG3658@2|Bacteria,1RB03@1224|Proteobacteria,1S9SA@1236|Gammaproteobacteria,1XVCJ@135623|Vibrionales	135623|Vibrionales	C	Prokaryotic cytochrome b561	-	-	-	-	-	-	-	-	-	-	-	-	Ni_hydr_CYTB
k141_5188_4	932213.SPM24T3_07814	2.84e-188	536.0	COG0738@1|root,COG0738@2|Bacteria,1MXDC@1224|Proteobacteria,1RQX9@1236|Gammaproteobacteria,402XR@613|Serratia	1236|Gammaproteobacteria	G	Major Facilitator Superfamily	gluP	-	-	ko:K02429	-	-	-	-	ko00000,ko02000	2.A.1.7	-	-	MFS_1
k141_5188_5	28152.DJ57_2120	7.5e-132	385.0	COG0837@1|root,COG0837@2|Bacteria,1MVFI@1224|Proteobacteria,1RNUY@1236|Gammaproteobacteria,41DWS@629|Yersinia	1236|Gammaproteobacteria	F	Belongs to the bacterial glucokinase family	glk	GO:0003674,GO:0003824,GO:0004340,GO:0004396,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019200,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046835,GO:0046939,GO:0051156,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	iNRG857_1313.NRG857_12000	Glucokinase
k141_5188_6	1348635.BBJY01000010_gene1428	1.15e-250	697.0	COG1823@1|root,COG1823@2|Bacteria,1R3F8@1224|Proteobacteria,1RMHV@1236|Gammaproteobacteria,1XUK9@135623|Vibrionales	135623|Vibrionales	U	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family	-	-	-	ko:K06956	-	-	-	-	ko00000	-	-	-	SDF
k141_5188_7	1348635.BBJY01000010_gene1278	7.92e-65	202.0	COG1846@1|root,COG1846@2|Bacteria,1RH1F@1224|Proteobacteria,1S8WM@1236|Gammaproteobacteria,1XXDE@135623|Vibrionales	135623|Vibrionales	K	COG1846 Transcriptional regulators	ohrR	-	-	-	-	-	-	-	-	-	-	-	MarR
k141_5188_8	530564.Psta_2591	2.74e-46	161.0	2CHWN@1|root,32TNN@2|Bacteria,2J2VB@203682|Planctomycetes	203682|Planctomycetes	S	Suppressor of fused protein (SUFU)	-	-	-	-	-	-	-	-	-	-	-	-	SUFU
k141_5188_9	945543.VIBR0546_17113	1.04e-267	757.0	COG0826@1|root,COG0826@2|Bacteria,1MUQG@1224|Proteobacteria,1RN7S@1236|Gammaproteobacteria,1XUBV@135623|Vibrionales	135623|Vibrionales	O	COG0826 Collagenase and related proteases	-	-	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	DUF3656,Peptidase_U32
k141_5188_12	1348635.BBJY01000006_gene517	2.54e-93	276.0	COG4283@1|root,COG4283@2|Bacteria,1QHXP@1224|Proteobacteria,1S8S9@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF1706)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1706
k141_5188_13	1116375.VEJY3_05285	2.21e-14	71.6	28PVK@1|root,3316T@2|Bacteria,1R3HD@1224|Proteobacteria,1T682@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_4
k141_5188_14	1116375.VEJY3_05285	8.29e-182	512.0	28PVK@1|root,3316T@2|Bacteria,1R3HD@1224|Proteobacteria,1T682@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_4
k141_5188_16	946483.Cenrod_0346	6.52e-16	87.8	COG2199@1|root,COG3447@1|root,COG2199@2|Bacteria,COG3447@2|Bacteria,1RGCV@1224|Proteobacteria,2VRTC@28216|Betaproteobacteria	28216|Betaproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,HAMP,PAS_4,dCache_1
k141_5188_18	1219065.VPR01S_03_00950	5.73e-222	619.0	COG0019@1|root,COG0019@2|Bacteria,1MZ7Y@1224|Proteobacteria,1RQJ4@1236|Gammaproteobacteria,1XVHW@135623|Vibrionales	135623|Vibrionales	E	Pyridoxal-dependent decarboxylase, pyridoxal binding domain	-	-	4.1.1.17	ko:K01581	ko00330,ko00480,ko01100,ko01110,ko01130,map00330,map00480,map01100,map01110,map01130	M00134	R00670	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
k141_5188_19	1396141.BATP01000032_gene4306	7.53e-51	177.0	COG0823@1|root,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_5188_20	1278307.KB907007_gene185	8.88e-181	517.0	COG3681@1|root,COG3681@2|Bacteria,1MW81@1224|Proteobacteria,1RP1R@1236|Gammaproteobacteria,2QIR9@267894|Psychromonadaceae	1236|Gammaproteobacteria	S	Serine dehydratase alpha chain	-	-	-	-	-	-	-	-	-	-	-	-	SDH_alpha
k141_5188_21	589873.EP13_11030	2.69e-167	476.0	COG2041@1|root,COG2041@2|Bacteria,1MUW0@1224|Proteobacteria,1RQ2J@1236|Gammaproteobacteria,464E2@72275|Alteromonadaceae	1236|Gammaproteobacteria	C	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide	msrP	GO:0000302,GO:0001101,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009987,GO:0010035,GO:0016491,GO:0016667,GO:0016672,GO:0016675,GO:0019538,GO:0030091,GO:0030288,GO:0030313,GO:0031975,GO:0042221,GO:0042597,GO:0043170,GO:0043546,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0048037,GO:0050662,GO:0050896,GO:0055114,GO:0071704,GO:0097159,GO:1901363,GO:1901530,GO:1901564,GO:1901700	-	ko:K07147	-	-	-	-	ko00000,ko01000	-	-	-	Oxidored_molyb
k141_5188_22	1001530.BACE01000027_gene754	7.17e-42	148.0	COG2717@1|root,COG2717@2|Bacteria,1RDUP@1224|Proteobacteria,1RS9K@1236|Gammaproteobacteria,1XWV1@135623|Vibrionales	135623|Vibrionales	C	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain	msrQ	-	-	ko:K17247	-	-	-	-	ko00000	-	-	-	Ferric_reduct
k141_5188_23	526222.Desal_1342	1.19e-69	222.0	2EFNH@1|root,339EN@2|Bacteria,1PU33@1224|Proteobacteria,435XC@68525|delta/epsilon subdivisions,2X0DX@28221|Deltaproteobacteria,2MBZ3@213115|Desulfovibrionales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_5188_24	675806.VII_001823	1.35e-36	127.0	2DTB0@1|root,33JH6@2|Bacteria,1NPKK@1224|Proteobacteria,1SJBY@1236|Gammaproteobacteria,1XY5Y@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_5188_26	1348635.BBJY01000011_gene1200	1.8e-105	313.0	COG0500@1|root,COG2226@2|Bacteria,1MXDY@1224|Proteobacteria,1RMU7@1236|Gammaproteobacteria,1XTTF@135623|Vibrionales	135623|Vibrionales	H	COG0500 SAM-dependent methyltransferases	rrmA	-	2.1.1.187	ko:K00563	-	-	R07233	RC00003	ko00000,ko01000,ko03009	-	-	-	Methyltransf_25,Methyltransf_31
k141_5188_27	1238450.VIBNISOn1_710006	1.26e-131	382.0	COG0676@1|root,COG0676@2|Bacteria,1Q7VN@1224|Proteobacteria,1RQK0@1236|Gammaproteobacteria,1XSYW@135623|Vibrionales	135623|Vibrionales	G	Belongs to the glucose-6-phosphate 1-epimerase family	-	-	5.1.3.15	ko:K01792	ko00010,ko01100,ko01110,ko01120,ko01130,map00010,map01100,map01110,map01120,map01130	-	R02739	RC00563	ko00000,ko00001,ko01000	-	-	-	Aldose_epim
k141_5188_28	675817.VDA_001583	5.02e-212	588.0	COG0057@1|root,COG0057@2|Bacteria,1MU93@1224|Proteobacteria,1RMBM@1236|Gammaproteobacteria,1XTWD@135623|Vibrionales	135623|Vibrionales	C	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	gapA	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
k141_5188_29	1116375.VEJY3_11150	1.62e-67	209.0	COG0229@1|root,COG0229@2|Bacteria,1RGWC@1224|Proteobacteria,1S5WI@1236|Gammaproteobacteria,1XXFA@135623|Vibrionales	135623|Vibrionales	C	Belongs to the MsrB Met sulfoxide reductase family	msrB	-	1.8.4.12	ko:K07305	-	-	-	-	ko00000,ko01000	-	-	-	SelR
k141_5188_30	55601.VANGNB10_cI0938c	1.57e-101	304.0	2CF8J@1|root,2Z7JD@2|Bacteria,1MYC8@1224|Proteobacteria,1RPF0@1236|Gammaproteobacteria,1XTQQ@135623|Vibrionales	135623|Vibrionales	S	Protein of unknown function (DUF2989)	VC1997	-	-	-	-	-	-	-	-	-	-	-	DUF2989
k141_5188_32	55601.VANGNB10_cI0941c	2.73e-268	754.0	COG0616@1|root,COG0616@2|Bacteria,1MUXE@1224|Proteobacteria,1RNYW@1236|Gammaproteobacteria,1XT9K@135623|Vibrionales	135623|Vibrionales	OU	signal peptide peptidase	sppA	-	-	ko:K04773	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S49
k141_5188_33	1348635.BBJY01000011_gene1190	3.28e-172	483.0	COG0788@1|root,COG0788@2|Bacteria,1MVCF@1224|Proteobacteria,1RN6Q@1236|Gammaproteobacteria,1XSK8@135623|Vibrionales	135623|Vibrionales	F	Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)	purU	-	3.5.1.10	ko:K01433	ko00630,ko00670,map00630,map00670	-	R00944	RC00026,RC00111	ko00000,ko00001,ko01000	-	-	-	ACT,Formyl_trans_N
k141_5188_34	675806.VII_001837	3.47e-25	95.1	2B7ZD@1|root,3216R@2|Bacteria,1QK8H@1224|Proteobacteria,1TIBZ@1236|Gammaproteobacteria,1XYUD@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_5188_35	345073.VC395_2105	0.0	1020.0	COG1199@1|root,COG1199@2|Bacteria,1MVCU@1224|Proteobacteria,1RMNX@1236|Gammaproteobacteria,1XSPF@135623|Vibrionales	135623|Vibrionales	KL	ATP-dependent helicase	yoaA	-	3.6.4.12	ko:K03722	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DEAD_2,Helicase_C_2,ResIII
k141_5188_36	1517681.HW45_05360	1.27e-103	306.0	COG1214@1|root,COG1214@2|Bacteria,1MXPH@1224|Proteobacteria,1RPYX@1236|Gammaproteobacteria,1XTAV@135623|Vibrionales	135623|Vibrionales	O	COG1214 Inactive homolog of metal-dependent proteases	tsaB	-	-	ko:K14742	-	-	-	-	ko00000,ko03016	-	-	-	Peptidase_M22
k141_5188_37	1051646.VITU9109_00957	5.71e-27	102.0	2AWHA@1|root,31NDU@2|Bacteria,1QK4W@1224|Proteobacteria,1TI80@1236|Gammaproteobacteria,1XYKX@135623|Vibrionales	135623|Vibrionales	-	-	VV1050	-	-	-	-	-	-	-	-	-	-	-	-
k141_5188_38	66269.NL54_13745	6.14e-21	92.8	COG3065@1|root,COG3065@2|Bacteria,1MZ8C@1224|Proteobacteria,1SDNR@1236|Gammaproteobacteria,3W2QF@53335|Pantoea	1236|Gammaproteobacteria	M	outer membrane lipoprotein, Slp family (NCBI ZP_05728595.1)	yeaY	-	-	ko:K07285	-	-	-	-	ko00000	-	-	-	Slp
k141_5188_39	675814.VIC_001729	6.75e-82	255.0	COG2267@1|root,COG2267@2|Bacteria,1QTAP@1224|Proteobacteria,1S6CX@1236|Gammaproteobacteria,1XSDM@135623|Vibrionales	135623|Vibrionales	I	hydrolases or acyltransferases (alpha beta hydrolase superfamily)	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
k141_5188_40	1187848.AJYQ01000063_gene264	6.83e-24	100.0	COG0349@1|root,COG0349@2|Bacteria,1MURV@1224|Proteobacteria,1RPBP@1236|Gammaproteobacteria,1XSSU@135623|Vibrionales	135623|Vibrionales	J	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides	rnd	-	3.1.13.5	ko:K03684	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DNA_pol_A_exo1,HRDC
k141_4207_1	1187848.AJYQ01000041_gene1	1.01e-70	261.0	COG3170@1|root,COG3170@2|Bacteria,1MXV7@1224|Proteobacteria,1RMM5@1236|Gammaproteobacteria,1XUV6@135623|Vibrionales	135623|Vibrionales	NU	COG3170 Tfp pilus assembly protein FimV	-	-	-	ko:K08086	-	-	-	-	ko00000	-	-	-	-
k141_4207_2	1348635.BBJY01000012_gene1109	0.0	1043.0	COG0008@1|root,COG0008@2|Bacteria,1MUC8@1224|Proteobacteria,1RQ7G@1236|Gammaproteobacteria,1XV77@135623|Vibrionales	135623|Vibrionales	J	COG0008 Glutamyl- and glutaminyl-tRNA synthetases	glnS	GO:0003674,GO:0003824,GO:0004812,GO:0004819,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006425,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.18	ko:K01886	ko00970,ko01100,map00970,map01100	M00359,M00360	R03652	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1c,tRNA-synt_1c_C
k141_4207_3	55601.VANGNB10_cI0865c	1.85e-223	624.0	COG1846@1|root,COG1940@1|root,COG1846@2|Bacteria,COG1940@2|Bacteria,1NFM0@1224|Proteobacteria,1RNEA@1236|Gammaproteobacteria,1XT2N@135623|Vibrionales	135623|Vibrionales	K	COG1940 Transcriptional regulator sugar kinase	nagC	-	-	ko:K02565	-	-	-	-	ko00000,ko03000	-	-	-	MarR,ROK
k141_4207_4	1348635.BBJY01000012_gene1114	0.0	1051.0	COG0367@1|root,COG0367@2|Bacteria,1MW4E@1224|Proteobacteria,1RQ7D@1236|Gammaproteobacteria,1XSW2@135623|Vibrionales	135623|Vibrionales	E	Asparagine synthetase B	asnB	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
k141_4207_5	55601.VANGNB10_cI0862	1.96e-79	239.0	COG0250@1|root,COG0250@2|Bacteria,1N01W@1224|Proteobacteria,1S91B@1236|Gammaproteobacteria,1XX33@135623|Vibrionales	135623|Vibrionales	K	Enhances distal genes transcription elongation in a specialized subset of operons that encode extracytoplasmic components	rfaH	-	-	ko:K05785	-	-	-	-	ko00000,ko03000	-	-	-	NusG
k141_4207_6	345073.VC395_1002	1.83e-162	462.0	COG0276@1|root,COG0276@2|Bacteria,1MVR1@1224|Proteobacteria,1RMMS@1236|Gammaproteobacteria,1XUVQ@135623|Vibrionales	135623|Vibrionales	H	Catalyzes the ferrous insertion into protoporphyrin IX	hemH	GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.99.1.1,4.99.1.9	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R00310,R11329	RC01012	ko00000,ko00001,ko00002,ko01000	-	-	-	Ferrochelatase
k141_4207_7	675813.VIB_001709	3.52e-140	397.0	COG0563@1|root,COG0563@2|Bacteria,1MXCZ@1224|Proteobacteria,1RMT6@1236|Gammaproteobacteria,1XT6A@135623|Vibrionales	135623|Vibrionales	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	GO:0003674,GO:0003824,GO:0004017,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK,ADK_lid
k141_4043_1	1121396.KB892957_gene3246	1.77e-117	359.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,42NC7@68525|delta/epsilon subdivisions,2WMHV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	-	ko:K12950	-	-	-	-	ko00000,ko01000	3.A.3.32	-	-	E1-E2_ATPase,Hydrolase
k141_2637_1	345073.VC395_1532	8.16e-26	112.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,1XTQG@135623|Vibrionales	135623|Vibrionales	NT	methyl-accepting chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal,dCache_1
k141_948_1	234267.Acid_5980	3.55e-94	301.0	COG0488@1|root,COG0488@2|Bacteria,3Y2H0@57723|Acidobacteria	57723|Acidobacteria	S	PFAM ABC transporter	-	-	-	ko:K15738	-	-	-	-	ko00000,ko02000	3.A.1.120.6	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
k141_949_1	675813.VIB_002225	7.13e-182	518.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,1RPN9@1236|Gammaproteobacteria,1XSW1@135623|Vibrionales	135623|Vibrionales	S	COG0488 ATPase components of ABC transporters with duplicated ATPase domains	ybiT	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,ABC_tran_Xtn
k141_949_2	1565129.JSFF01000007_gene1554	2.45e-92	287.0	COG0840@1|root,COG2703@1|root,COG0840@2|Bacteria,COG2703@2|Bacteria,1RBB1@1224|Proteobacteria,1S265@1236|Gammaproteobacteria,2Q9DW@267890|Shewanellaceae	1236|Gammaproteobacteria	NPT	Hemerythrin HHE cation binding domain protein	-	-	-	ko:K07216	-	-	-	-	ko00000	-	-	-	Hemerythrin,MCPsignal
k141_5062_1	1121403.AUCV01000005_gene210	7.76e-130	380.0	COG0604@1|root,COG0604@2|Bacteria,1MV3W@1224|Proteobacteria,42MXJ@68525|delta/epsilon subdivisions,2WKAC@28221|Deltaproteobacteria,2MJ1T@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Zinc-binding dehydrogenase	acuI	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
k141_5062_2	335543.Sfum_3689	4.63e-62	199.0	COG1309@1|root,COG1309@2|Bacteria,1PFBP@1224|Proteobacteria,43A4U@68525|delta/epsilon subdivisions,2X2CD@28221|Deltaproteobacteria,2MSAM@213462|Syntrophobacterales	28221|Deltaproteobacteria	K	Bacterial transcriptional repressor C-terminal	-	-	-	ko:K16137	-	-	-	-	ko00000,ko03000	-	-	-	TetR_C_13,TetR_N
k141_5062_3	272952.HpaP803601	7.74e-30	119.0	COG1694@1|root,2S210@2759|Eukaryota,3QAV6@4776|Peronosporales	4776|Peronosporales	S	MazG-like family	-	-	-	-	-	-	-	-	-	-	-	-	MazG-like
k141_5064_1	1238182.C882_4398	4.73e-26	107.0	COG1262@1|root,COG1262@2|Bacteria,1NQ5K@1224|Proteobacteria,2U2VJ@28211|Alphaproteobacteria,2JS16@204441|Rhodospirillales	204441|Rhodospirillales	T	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
k141_5065_1	439235.Dalk_4397	1.35e-07	53.5	COG0498@1|root,COG0498@2|Bacteria,1MUWQ@1224|Proteobacteria,42M1W@68525|delta/epsilon subdivisions,2WK53@28221|Deltaproteobacteria,2MIJV@213118|Desulfobacterales	28221|Deltaproteobacteria	E	TIGRFAM threonine synthase	thrC	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
k141_5065_2	933262.AXAM01000008_gene1973	5.36e-18	86.7	COG1388@1|root,COG1388@2|Bacteria,1R9WA@1224|Proteobacteria,42RAT@68525|delta/epsilon subdivisions,2WN3X@28221|Deltaproteobacteria,2MJI1@213118|Desulfobacterales	28221|Deltaproteobacteria	M	LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	LysM
k141_951_1	1123070.KB899253_gene1042	1.4e-28	112.0	COG1752@1|root,COG1752@2|Bacteria,46WCV@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Patatin-like phospholipase	-	-	-	-	-	-	-	-	-	-	-	-	Patatin
k141_951_2	643562.Daes_1804	4.3e-157	461.0	COG1502@1|root,COG1502@2|Bacteria,1MWUW@1224|Proteobacteria,42PV9@68525|delta/epsilon subdivisions,2WKF2@28221|Deltaproteobacteria,2M93H@213115|Desulfovibrionales	28221|Deltaproteobacteria	I	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol	cls	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2,PLDc_N
k141_5067_1	439235.Dalk_4144	1.39e-234	681.0	COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1145@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1145@2|Bacteria,1MVM0@1224|Proteobacteria,42MZ0@68525|delta/epsilon subdivisions,2WJ96@28221|Deltaproteobacteria,2MHRJ@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	poR	-	1.2.7.1	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00173,M00307	R01196,R10866	RC00004,RC02742	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	EKR,Fer4_16,PFOR_II,POR,POR_N,TPP_enzyme_C
k141_1611_1	55601.VANGNB10_cI0424c	7.12e-95	294.0	COG0358@1|root,COG0358@2|Bacteria,1MUHC@1224|Proteobacteria,1RMGA@1236|Gammaproteobacteria,1XUTH@135623|Vibrionales	135623|Vibrionales	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB_bind,DnaG_DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2
k141_1611_3	880074.BARVI_03810	3.85e-125	372.0	COG1479@1|root,COG1479@2|Bacteria,4NRVQ@976|Bacteroidetes,2FTAB@200643|Bacteroidia,22YPV@171551|Porphyromonadaceae	976|Bacteroidetes	S	Protein of unknown function DUF262	-	-	-	-	-	-	-	-	-	-	-	-	DUF262
k141_4044_2	672.VV93_v1c40960	2.93e-224	632.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,1RMWA@1236|Gammaproteobacteria,1XSNZ@135623|Vibrionales	135623|Vibrionales	F	DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA	rhlE	-	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
k141_4044_3	493475.GARC_5027	2.74e-09	62.0	COG5463@1|root,COG5463@2|Bacteria,1MXGU@1224|Proteobacteria,1RPEV@1236|Gammaproteobacteria,466H9@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	integral membrane protein	ygiB	GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF1190
k141_4044_5	672.VV93_v1c18360	4e-82	246.0	2AQ2U@1|root,31F7Z@2|Bacteria,1R8TD@1224|Proteobacteria,1S0VX@1236|Gammaproteobacteria,1XWZE@135623|Vibrionales	135623|Vibrionales	S	Protein of unknown function (DUF2947)	VV12273	-	-	-	-	-	-	-	-	-	-	-	DUF2947
k141_4044_6	945543.VIBR0546_15306	3.43e-83	251.0	COG1896@1|root,COG1896@2|Bacteria,1MXEZ@1224|Proteobacteria,1RRQQ@1236|Gammaproteobacteria,1XUSC@135623|Vibrionales	135623|Vibrionales	S	hydrolases of HD superfamily	-	-	-	ko:K07023	-	-	-	-	ko00000	-	-	-	HD_3
k141_4044_7	675814.VIC_001440	1.78e-80	244.0	COG1670@1|root,COG1670@2|Bacteria,1MVG4@1224|Proteobacteria,1RQPX@1236|Gammaproteobacteria,1XV1R@135623|Vibrionales	135623|Vibrionales	J	COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins	rimJ	-	2.3.1.128	ko:K03790	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_3
k141_4044_8	1348635.BBJY01000015_gene695	4.15e-211	596.0	COG3283@1|root,COG3283@2|Bacteria,1QTS3@1224|Proteobacteria,1RNAI@1236|Gammaproteobacteria,1XSF4@135623|Vibrionales	135623|Vibrionales	K	COG3283 Transcriptional regulator of aromatic amino acids metabolism	tyrR	-	-	ko:K03721	-	-	-	-	ko00000,ko03000	-	-	-	PAS,PAS_8,Sigma54_activat
k141_1612_1	933262.AXAM01000005_gene2458	1.84e-66	218.0	COG0860@1|root,COG0860@2|Bacteria,1MUQK@1224|Proteobacteria,42MPH@68525|delta/epsilon subdivisions,2WJHW@28221|Deltaproteobacteria,2MHPG@213118|Desulfobacterales	28221|Deltaproteobacteria	M	N-acetylmuramoyl-L-alanine amidase	amiC	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	AMIN,Amidase_3,TPR_6
k141_952_1	298386.PBPRA2543	6.43e-148	422.0	COG2378@1|root,COG2378@2|Bacteria,1Q19K@1224|Proteobacteria,1RZ1N@1236|Gammaproteobacteria,1XUZ2@135623|Vibrionales	135623|Vibrionales	K	WYL domain	-	-	-	-	-	-	-	-	-	-	-	-	WYL
k141_952_2	298386.PBPRC0040	4.95e-63	215.0	COG1203@1|root,COG1203@2|Bacteria,1MX99@1224|Proteobacteria,1RMM0@1236|Gammaproteobacteria,1XXC7@135623|Vibrionales	135623|Vibrionales	L	DEAD-like helicases superfamily	-	-	-	ko:K07012	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	DEAD,Helicase_C
k141_1613_2	1121405.dsmv_2348	4.29e-10	61.2	COG0631@1|root,COG0631@2|Bacteria,1R7UF@1224|Proteobacteria,42QUA@68525|delta/epsilon subdivisions,2WMWM@28221|Deltaproteobacteria,2MJKU@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Serine/threonine phosphatases, family 2C, catalytic domain	-	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C_2
k141_5068_2	1116375.VEJY3_10425	6.79e-140	402.0	COG1237@1|root,COG1237@2|Bacteria,1NK2I@1224|Proteobacteria,1RSGM@1236|Gammaproteobacteria,1XVHI@135623|Vibrionales	135623|Vibrionales	S	COG1237 Metal-dependent hydrolases of the beta-lactamase superfamily II	-	-	2.5.1.105	ko:K06897	ko00790,map00790	-	R10339	RC00121	ko00000,ko00001,ko01000	-	-	-	Lactamase_B
k141_5071_1	765913.ThidrDRAFT_2582	1.84e-86	267.0	COG1131@1|root,COG1131@2|Bacteria,1R3XF@1224|Proteobacteria,1S1UI@1236|Gammaproteobacteria,1X0I2@135613|Chromatiales	135613|Chromatiales	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
k141_5071_2	1122971.BAME01000064_gene4750	4.48e-10	61.2	2CA2P@1|root,32RQH@2|Bacteria,4NS81@976|Bacteroidetes,2FM4W@200643|Bacteroidia,22XND@171551|Porphyromonadaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_954_1	1238450.VIBNISOn1_340029	5.5e-287	806.0	COG3501@1|root,COG3501@2|Bacteria,1MU7Q@1224|Proteobacteria,1RMZS@1236|Gammaproteobacteria,1XUHW@135623|Vibrionales	135623|Vibrionales	M	protein conserved in bacteria	-	-	-	ko:K11904	ko03070,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	PG_binding_1,Phage_GPD
k141_954_2	672.VV93_v1c39190	3.35e-40	161.0	COG3209@1|root,COG3209@2|Bacteria,1MVV1@1224|Proteobacteria,1SKYM@1236|Gammaproteobacteria,1XW76@135623|Vibrionales	135623|Vibrionales	M	COG3209 Rhs family protein	-	-	-	-	-	-	-	-	-	-	-	-	Ntox15,RHS,RHS_repeat
k141_1614_2	1121405.dsmv_3300	5.58e-118	347.0	COG0063@1|root,COG0063@2|Bacteria,1R3U6@1224|Proteobacteria,42NVK@68525|delta/epsilon subdivisions,2WJZE@28221|Deltaproteobacteria,2MIH2@213118|Desulfobacterales	28221|Deltaproteobacteria	G	Carbohydrate kinase	-	-	-	-	-	-	-	-	-	-	-	-	Carb_kinase
k141_1614_3	96561.Dole_3247	2.51e-82	248.0	arCOG05017@1|root,3015V@2|Bacteria,1RDNC@1224|Proteobacteria,42RJ5@68525|delta/epsilon subdivisions,2WNJP@28221|Deltaproteobacteria,2MJGW@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF3343)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3343
k141_1644_3	55601.VANGNB10_cI1391c	6.93e-216	609.0	COG3106@1|root,COG3106@2|Bacteria,1MX6E@1224|Proteobacteria,1RQ05@1236|Gammaproteobacteria,1XT2C@135623|Vibrionales	135623|Vibrionales	S	YcjX-like family, DUF463	ycjX	-	-	ko:K06918	-	-	-	-	ko00000	-	-	-	DUF463
k141_1644_4	312309.VF_A0749	1e-14	68.6	29VTS@1|root,30HBD@2|Bacteria,1QTBG@1224|Proteobacteria,1TIE4@1236|Gammaproteobacteria,1XYYM@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_1644_5	243277.VC_1304	0.0	881.0	COG1838@1|root,COG1951@1|root,COG1838@2|Bacteria,COG1951@2|Bacteria,1MUV9@1224|Proteobacteria,1RN8U@1236|Gammaproteobacteria,1XT4K@135623|Vibrionales	135623|Vibrionales	C	Catalyzes the reversible hydration of fumarate to (S)- malate	fumB	-	4.2.1.2	ko:K01676	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumerase,Fumerase_C
k141_1644_6	345073.VC395_1422	5.5e-191	544.0	COG0147@1|root,COG0147@2|Bacteria,1MVBJ@1224|Proteobacteria,1RMSE@1236|Gammaproteobacteria,1XTES@135623|Vibrionales	135623|Vibrionales	EH	COG0147 Anthranilate para-aminobenzoate synthases component I	pabB	-	2.6.1.85	ko:K01665	ko00790,map00790	-	R01716	RC00010,RC01418	ko00000,ko00001,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
k141_1644_7	29495.EA26_06925	7.27e-63	200.0	COG0494@1|root,COG0494@2|Bacteria,1RD2C@1224|Proteobacteria,1SA4Q@1236|Gammaproteobacteria,1XWY8@135623|Vibrionales	135623|Vibrionales	L	COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes	nudL	-	-	-	-	-	-	-	-	-	-	-	NUDIX
k141_1644_8	90371.CY43_09325	3.65e-227	637.0	COG1760@1|root,COG1760@2|Bacteria,1MUZN@1224|Proteobacteria,1RMJZ@1236|Gammaproteobacteria,3ZKGG@590|Salmonella	1236|Gammaproteobacteria	E	Serine dehydratase beta chain	sdaA	GO:0003674,GO:0003824,GO:0003941,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006563,GO:0006565,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009069,GO:0009071,GO:0009987,GO:0016054,GO:0016829,GO:0016840,GO:0016841,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	4.3.1.17	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	-	R00220,R00590	RC00331,RC02600	ko00000,ko00001,ko01000	-	-	iECUMN_1333.ECUMN_2106	SDH_alpha,SDH_beta
k141_1644_9	675815.VOA_002039	2.93e-95	284.0	2EAF8@1|root,334IN@2|Bacteria,1ND4K@1224|Proteobacteria,1SBS5@1236|Gammaproteobacteria,1XTF7@135623|Vibrionales	135623|Vibrionales	S	Protein of unknown function (DUF2913)	VP1217	-	-	-	-	-	-	-	-	-	-	-	DUF2913
k141_1644_10	55601.VANGNB10_cI1158	1.06e-171	492.0	COG0477@1|root,COG2814@2|Bacteria,1MW19@1224|Proteobacteria,1RMSZ@1236|Gammaproteobacteria,1XSKM@135623|Vibrionales	135623|Vibrionales	EGP	of the major facilitator superfamily	bcr	-	-	ko:K07552	-	-	-	-	ko00000,ko02000	2.A.1.2	-	-	MFS_1
k141_1644_12	55601.VANGNB10_cI1157	9.8e-128	367.0	COG1187@1|root,COG1187@2|Bacteria,1MU6M@1224|Proteobacteria,1RQA9@1236|Gammaproteobacteria,1XTEX@135623|Vibrionales	135623|Vibrionales	J	Belongs to the pseudouridine synthase RsuA family	rsuA	GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	5.4.99.19	ko:K06183	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
k141_1644_13	1348635.BBJY01000015_gene768	0.0	905.0	COG1061@1|root,COG1061@2|Bacteria,1MV9F@1224|Proteobacteria,1RNAN@1236|Gammaproteobacteria,1XV70@135623|Vibrionales	135623|Vibrionales	KL	COG1061 DNA or RNA helicases of superfamily II	yejH	-	-	ko:K19789	-	-	-	-	ko00000,ko03400	-	-	-	Helicase_C,ResIII
k141_1644_14	1238450.VIBNISOn1_1540016	1.42e-51	163.0	COG1825@1|root,COG1825@2|Bacteria,1RDH0@1224|Proteobacteria,1S46A@1236|Gammaproteobacteria,1XXXW@135623|Vibrionales	135623|Vibrionales	J	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance	rplY	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02897	ko03010,map03010	M00178	-	-	ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L25p
k141_1644_15	1190603.AJYD01000028_gene3791	2.22e-135	406.0	COG1368@1|root,COG1368@2|Bacteria,1MVCM@1224|Proteobacteria,1RNJ3@1236|Gammaproteobacteria,1XVBR@135623|Vibrionales	135623|Vibrionales	M	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
k141_1645_1	1123274.KB899431_gene3277	1.19e-34	124.0	COG1664@1|root,COG1664@2|Bacteria,2J82J@203691|Spirochaetes	203691|Spirochaetes	M	Integral membrane protein CcmA involved in cell shape determination	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
k141_1645_2	1502851.FG93_00234	1.45e-09	60.1	COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,2TT3Z@28211|Alphaproteobacteria,3JTRT@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	M	Peptidase family M23	MA20_20375	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
k141_964_1	1487921.DP68_00935	5.67e-51	176.0	COG1690@1|root,COG1690@2|Bacteria,1TPJ2@1239|Firmicutes,2481V@186801|Clostridia,36EU8@31979|Clostridiaceae	186801|Clostridia	S	tRNA-splicing ligase RtcB	-	-	6.5.1.3	ko:K14415,ko:K18148	ko01501,map01501	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	RtcB
k141_1646_1	555779.Dthio_PD1857	2.4e-17	86.7	COG0642@1|root,COG5002@1|root,COG0642@2|Bacteria,COG2205@2|Bacteria,COG5002@2|Bacteria,1NRP8@1224|Proteobacteria,42M0Y@68525|delta/epsilon subdivisions,2WJCX@28221|Deltaproteobacteria,2MH92@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	PFAM ATP-binding region ATPase domain protein	-	-	2.7.13.3	ko:K07678	ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111	M00475	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	7TMR-DISMED2,7TMR-DISM_7TM,DUF3365,HAMP,HATPase_c,HisKA,Hpt,PAS_4,PAS_9,Response_reg
k141_5337_1	879212.DespoDRAFT_00475	8.59e-146	431.0	COG0446@1|root,COG1902@1|root,COG0446@2|Bacteria,COG1902@2|Bacteria,1MVE0@1224|Proteobacteria,42PDA@68525|delta/epsilon subdivisions,2WK05@28221|Deltaproteobacteria,2MHS3@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM NADH flavin oxidoreductase NADH oxidase	-	-	1.3.1.34	ko:K00219	-	-	-	-	ko00000,ko01000	-	-	-	Oxidored_FMN,Pyr_redox_2
k141_4078_1	1304885.AUEY01000009_gene1941	2.67e-23	100.0	COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,42MEA@68525|delta/epsilon subdivisions,2WIW6@28221|Deltaproteobacteria,2MINT@213118|Desulfobacterales	28221|Deltaproteobacteria	K	Sigma-54 interaction domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HTH_8,Sigma54_activat
k141_4078_2	525897.Dbac_2356	1.43e-91	289.0	COG0477@1|root,COG0477@2|Bacteria,1MWUR@1224|Proteobacteria,43BPW@68525|delta/epsilon subdivisions,2X714@28221|Deltaproteobacteria,2MHA9@213115|Desulfovibrionales	28221|Deltaproteobacteria	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
k141_967_1	177437.HRM2_26920	3.68e-74	233.0	COG0340@1|root,COG1654@1|root,COG0340@2|Bacteria,COG1654@2|Bacteria,1MWCC@1224|Proteobacteria,42P6I@68525|delta/epsilon subdivisions,2WMAF@28221|Deltaproteobacteria,2MIAS@213118|Desulfobacterales	28221|Deltaproteobacteria	HK	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor	birA	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_C,BPL_LplA_LipB,HTH_11
k141_5338_2	1348635.BBJY01000006_gene326	2.79e-171	488.0	COG1925@1|root,COG4668@1|root,COG1925@2|Bacteria,COG4668@2|Bacteria,1MVP6@1224|Proteobacteria,1RQP4@1236|Gammaproteobacteria,1XSJ1@135623|Vibrionales	135623|Vibrionales	G	COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain	fruB	-	2.7.1.202	ko:K02768,ko:K11183	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	M00273	R03232	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.2.1	-	-	PTS-HPr,PTS_EIIA_2
k141_1647_1	706587.Desti_3990	5.18e-84	259.0	COG0778@1|root,COG1148@1|root,COG0778@2|Bacteria,COG1148@2|Bacteria,1R4E3@1224|Proteobacteria,42RVJ@68525|delta/epsilon subdivisions,2WNCQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM Nitroreductase	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_4,Nitroreductase
k141_1647_2	242619.PG_0124	4.15e-27	109.0	COG1739@1|root,COG1739@2|Bacteria,4NF0D@976|Bacteroidetes,2FQHX@200643|Bacteroidia,22WR7@171551|Porphyromonadaceae	976|Bacteroidetes	S	YigZ family	yigZ	-	-	-	-	-	-	-	-	-	-	-	UPF0029
k141_1647_3	1167006.UWK_01447	1.39e-21	100.0	COG3221@1|root,COG3221@2|Bacteria,1QVNP@1224|Proteobacteria	1224|Proteobacteria	P	ABC transporter, phosphonate, periplasmic substrate-binding protein	-	-	2.7.13.3	ko:K13040	ko02020,map02020	M00514	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	GerE,Phosphonate-bd
k141_968_2	177437.HRM2_43710	9.54e-47	152.0	COG3436@1|root,COG3436@2|Bacteria,1MYCD@1224|Proteobacteria,42TEE@68525|delta/epsilon subdivisions,2WPUG@28221|Deltaproteobacteria,2MPR3@213118|Desulfobacterales	28221|Deltaproteobacteria	L	PFAM IS66 Orf2 like protein	-	-	-	ko:K07484	-	-	-	-	ko00000	-	-	-	TnpB_IS66
k141_4383_2	1321778.HMPREF1982_04262	6.53e-213	597.0	COG0205@1|root,COG0205@2|Bacteria,1TRJQ@1239|Firmicutes,247IV@186801|Clostridia,2688K@186813|unclassified Clostridiales	186801|Clostridia	G	Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions	pfp	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
k141_4383_3	522772.Dacet_1991	4.53e-30	129.0	COG2199@1|root,COG3706@2|Bacteria	2|Bacteria	T	GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS,PAS_4
k141_4384_1	1219080.VEZ01S_07_01350	4.43e-86	272.0	COG0550@1|root,COG0550@2|Bacteria,1MUFZ@1224|Proteobacteria,1RN4X@1236|Gammaproteobacteria,1XUYY@135623|Vibrionales	135623|Vibrionales	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topB	GO:0003674,GO:0003824,GO:0003916,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016853,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360	5.99.1.2	ko:K03169	-	-	-	-	ko00000,ko01000,ko03032	-	-	-	Topoisom_bac,Toprim
k141_1648_1	177437.HRM2_18640	0.000937	42.4	COG0360@1|root,COG0360@2|Bacteria,1RH82@1224|Proteobacteria,42TJR@68525|delta/epsilon subdivisions,2WRDG@28221|Deltaproteobacteria,2MKEY@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Binds together with S18 to 16S ribosomal RNA	rpsF	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0097159,GO:1901363,GO:1990904	-	ko:K02990	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S6
k141_1648_2	667014.Thein_1689	1.43e-30	110.0	COG0238@1|root,COG0238@2|Bacteria,2GI1A@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	J	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit	rpsR	-	-	ko:K02963	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S18
k141_1648_3	1232437.KL662033_gene2675	3.86e-53	172.0	COG0359@1|root,COG0359@2|Bacteria,1RD0R@1224|Proteobacteria,42SCQ@68525|delta/epsilon subdivisions,2WPZQ@28221|Deltaproteobacteria,2MJFS@213118|Desulfobacterales	28221|Deltaproteobacteria	J	binds to the 23S rRNA	rplI	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02939	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L9_C,Ribosomal_L9_N
k141_1648_4	1123376.AUIU01000011_gene1049	6.53e-19	87.4	COG0305@1|root,COG0305@2|Bacteria,3J0EZ@40117|Nitrospirae	40117|Nitrospirae	L	Participates in initiation and elongation during chromosome replication	-	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
k141_971_1	318161.Sden_1137	1.2e-31	119.0	COG4974@1|root,COG4974@2|Bacteria,1MVAN@1224|Proteobacteria,1S1WF@1236|Gammaproteobacteria,2QEIK@267890|Shewanellaceae	1236|Gammaproteobacteria	L	Phage integrase, N-terminal SAM-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
k141_972_1	880072.Desac_1529	8.72e-40	140.0	COG1309@1|root,COG1309@2|Bacteria,1RCDH@1224|Proteobacteria,42VJ5@68525|delta/epsilon subdivisions,2WN7N@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	PFAM Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
k141_973_1	1380387.JADM01000007_gene609	3.17e-13	73.2	COG1309@1|root,COG1309@2|Bacteria,1RDYN@1224|Proteobacteria	1224|Proteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
k141_1651_1	1208321.D104_11430	4.5e-159	451.0	COG0444@1|root,COG0444@2|Bacteria,1R4KB@1224|Proteobacteria,1SMBI@1236|Gammaproteobacteria,1XI7K@135619|Oceanospirillales	135619|Oceanospirillales	P	Belongs to the ABC transporter superfamily	dppD	-	-	ko:K12371	ko02010,map02010	M00324	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
k141_1651_2	400668.Mmwyl1_0112	2.69e-33	122.0	COG1173@1|root,COG1173@2|Bacteria,1MUG0@1224|Proteobacteria,1RN08@1236|Gammaproteobacteria,1XIY8@135619|Oceanospirillales	135619|Oceanospirillales	EP	transporter	-	-	-	ko:K02034,ko:K12370	ko02010,ko02024,map02010,map02024	M00239,M00324	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
k141_974_1	1121403.AUCV01000043_gene87	1.93e-61	191.0	COG0454@1|root,COG0456@2|Bacteria,1QUS0@1224|Proteobacteria,42UYA@68525|delta/epsilon subdivisions,2WPZZ@28221|Deltaproteobacteria,2MKYE@213118|Desulfobacterales	28221|Deltaproteobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
k141_975_1	1322246.BN4_11384	2.99e-49	165.0	COG1309@1|root,COG1309@2|Bacteria,1NP72@1224|Proteobacteria,42T8H@68525|delta/epsilon subdivisions,2WPNA@28221|Deltaproteobacteria,2MASD@213115|Desulfovibrionales	28221|Deltaproteobacteria	K	regulatory protein TetR	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_6,TetR_N
k141_4385_2	55601.VANGNB10_cII0485c	2.67e-69	218.0	COG1357@1|root,COG1357@2|Bacteria,1QF5X@1224|Proteobacteria,1RMSN@1236|Gammaproteobacteria,1XSYF@135623|Vibrionales	135623|Vibrionales	S	Pentapeptide repeats (9 copies)	qnr	-	-	ko:K18555	-	M00729	-	-	ko00000,ko00002,ko01504	-	-	-	Pentapeptide
k141_4385_3	1128912.GMES_2450	4.31e-84	249.0	COG3791@1|root,COG3791@2|Bacteria,1N031@1224|Proteobacteria,1S8W1@1236|Gammaproteobacteria,467D7@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Glutathione-dependent formaldehyde-activating enzyme	-	-	-	-	-	-	-	-	-	-	-	-	GFA
k141_4385_4	1187848.AJYQ01000093_gene3496	2.56e-116	348.0	COG4974@1|root,COG4974@2|Bacteria,1QUDX@1224|Proteobacteria,1T1VB@1236|Gammaproteobacteria,1XX4U@135623|Vibrionales	135623|Vibrionales	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
k141_4386_1	223926.28810034	7.14e-61	196.0	COG2240@1|root,COG2240@2|Bacteria,1MVC9@1224|Proteobacteria,1RMIE@1236|Gammaproteobacteria,1XSHI@135623|Vibrionales	135623|Vibrionales	H	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP	pdxY	-	2.7.1.35	ko:K00868	ko00750,ko01100,map00750,map01100	-	R00174,R01909,R02493	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	Phos_pyr_kin
k141_1655_1	179408.Osc7112_4430	6.96e-41	154.0	COG0515@1|root,COG2203@1|root,COG3899@1|root,COG4191@1|root,COG0515@2|Bacteria,COG2203@2|Bacteria,COG3899@2|Bacteria,COG4191@2|Bacteria,1GD97@1117|Cyanobacteria,1HEHM@1150|Oscillatoriales	1117|Cyanobacteria	KLT	SMART Serine threonine-protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GAF,HATPase_c,HisKA,Pkinase,Response_reg
k141_4547_6	1235457.C404_01510	1.12e-46	170.0	COG2382@1|root,COG2382@2|Bacteria,1MXJN@1224|Proteobacteria,2VIJN@28216|Betaproteobacteria	28216|Betaproteobacteria	P	esterase	fes	-	-	ko:K07214	-	-	-	-	ko00000	-	-	-	DUF3327,Esterase
k141_4547_7	1219076.N646_2072	2.85e-23	105.0	COG3650@1|root,COG3650@2|Bacteria,1RIIM@1224|Proteobacteria,1S8NS@1236|Gammaproteobacteria,1XSAK@135623|Vibrionales	135623|Vibrionales	S	response to hydrogen peroxide	VP2977	-	-	ko:K08985	-	-	-	-	ko00000	-	-	-	-
k141_506_2	933262.AXAM01000072_gene2244	2.14e-83	248.0	COG1908@1|root,COG1908@2|Bacteria,1RCZY@1224|Proteobacteria,42RJZ@68525|delta/epsilon subdivisions,2WNDU@28221|Deltaproteobacteria,2MJUB@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Methyl-viologen-reducing hydrogenase, delta subunit	-	-	-	-	-	-	-	-	-	-	-	-	FlpD
k141_506_3	933262.AXAM01000072_gene2240	4.52e-54	189.0	COG1148@1|root,COG1148@2|Bacteria,1QUM4@1224|Proteobacteria,42MPP@68525|delta/epsilon subdivisions,2WJ3U@28221|Deltaproteobacteria,2MIJ3@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM Pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_7,Pyr_redox_2
k141_4883_2	717231.Flexsi_1003	6e-20	87.0	2DRTV@1|root,33D1E@2|Bacteria,2GFUB@200930|Deferribacteres	200930|Deferribacteres	S	Protein of unknown function (DUF2914)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2914
k141_4883_3	1304885.AUEY01000020_gene3508	7.05e-74	231.0	COG0494@1|root,COG0494@2|Bacteria,1RD2C@1224|Proteobacteria,42TAG@68525|delta/epsilon subdivisions	1224|Proteobacteria	L	PFAM NUDIX hydrolase	nudL	-	-	-	-	-	-	-	-	-	-	-	NUDIX
k141_1131_1	1348635.BBJY01000007_gene166	3.39e-116	347.0	2AG8V@1|root,316E7@2|Bacteria,1PXEQ@1224|Proteobacteria,1TIV5@1236|Gammaproteobacteria,1XZQY@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_1131_2	1348635.BBJY01000007_gene167	6.51e-203	565.0	2AGEB@1|root,316KA@2|Bacteria,1PXQP@1224|Proteobacteria,1TJ5Q@1236|Gammaproteobacteria,1Y0MH@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_1131_4	1348635.BBJY01000007_gene169	8.75e-32	112.0	COG0234@1|root,COG0234@2|Bacteria,1QMI9@1224|Proteobacteria,1TJTM@1236|Gammaproteobacteria,1Y1NT@135623|Vibrionales	135623|Vibrionales	O	Chaperonin 10 Kd subunit	-	-	-	-	-	-	-	-	-	-	-	-	Cpn10
k141_1131_5	1348635.BBJY01000007_gene170	8.86e-226	625.0	COG4974@1|root,COG4974@2|Bacteria,1MVNF@1224|Proteobacteria,1RPI8@1236|Gammaproteobacteria,1Y031@135623|Vibrionales	135623|Vibrionales	L	Phage integrase, N-terminal SAM-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_1,Phage_integrase
k141_1131_6	1348635.BBJY01000007_gene171	5.01e-71	218.0	COG3926@1|root,COG3926@2|Bacteria,1MVXW@1224|Proteobacteria,1RRB6@1236|Gammaproteobacteria,1Y0F2@135623|Vibrionales	135623|Vibrionales	S	Predicted Peptidoglycan domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_108,PG_binding_3
k141_4548_1	545694.TREPR_1260	0.00081	46.2	COG0642@1|root,COG0642@2|Bacteria,2JBJB@203691|Spirochaetes	2|Bacteria	T	Histidine Phosphotransfer domain	-	-	2.7.13.3	ko:K20974	ko02020,ko02025,map02020,map02025	M00820	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,Hpt,PAS_4,Response_reg,dCache_1
k141_4548_2	96561.Dole_0622	5.9e-69	218.0	COG0745@1|root,COG0745@2|Bacteria,1N5ZC@1224|Proteobacteria,42NII@68525|delta/epsilon subdivisions,2WJ2Z@28221|Deltaproteobacteria,2MHWN@213118|Desulfobacterales	28221|Deltaproteobacteria	T	PFAM response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
k141_4548_3	1265505.ATUG01000002_gene2202	6.98e-36	128.0	COG2840@1|root,COG2840@2|Bacteria,1RHC4@1224|Proteobacteria,42SUI@68525|delta/epsilon subdivisions,2WP6R@28221|Deltaproteobacteria,2MKC7@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Smr domain	-	-	-	-	-	-	-	-	-	-	-	-	Smr
k141_1132_1	879212.DespoDRAFT_01045	4.79e-95	286.0	COG0002@1|root,COG0002@2|Bacteria,1MVJ6@1224|Proteobacteria,42MDN@68525|delta/epsilon subdivisions,2WINX@28221|Deltaproteobacteria,2MI9X@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde	argC	-	1.2.1.38	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R03443	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
k141_4157_1	345073.VC395_1351	3.15e-33	120.0	COG1346@1|root,COG1346@2|Bacteria,1MV81@1224|Proteobacteria,1RS5C@1236|Gammaproteobacteria,1XT9T@135623|Vibrionales	135623|Vibrionales	M	effector of murein hydrolase	yohK	-	-	-	-	-	-	-	-	-	-	-	LrgB
k141_4157_2	55601.VANGNB10_cI1541	5.35e-77	243.0	COG0295@1|root,COG0295@2|Bacteria,1MY2R@1224|Proteobacteria,1RMRX@1236|Gammaproteobacteria,1XV0Z@135623|Vibrionales	135623|Vibrionales	F	This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis	cdd	GO:0003674,GO:0003824,GO:0004126,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006216,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008655,GO:0009056,GO:0009058,GO:0009116,GO:0009119,GO:0009164,GO:0009972,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042454,GO:0043094,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046087,GO:0046131,GO:0046133,GO:0046135,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:1901135,GO:1901136,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901657,GO:1901658	3.5.4.5	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01878,R02485,R08221	RC00074,RC00514	ko00000,ko00001,ko01000	-	-	-	dCMP_cyt_deam_1,dCMP_cyt_deam_2
k141_4157_3	1238450.VIBNISOn1_1160020	1.71e-210	590.0	COG0027@1|root,COG0027@2|Bacteria,1N3KA@1224|Proteobacteria,1RNTW@1236|Gammaproteobacteria,1XUDQ@135623|Vibrionales	135623|Vibrionales	F	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate	purT	GO:0003674,GO:0003824,GO:0004644,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016742,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.1.2.2	ko:K08289	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp,Epimerase
k141_4157_5	1348635.BBJY01000017_gene4164	0.0	1199.0	COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria,1MWKS@1224|Proteobacteria,1RMIH@1236|Gammaproteobacteria,1XSJE@135623|Vibrionales	135623|Vibrionales	J	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily	pheT	GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
k141_4884_1	96561.Dole_2822	1.29e-67	219.0	COG0564@1|root,COG0564@2|Bacteria,1MUBN@1224|Proteobacteria,42MBA@68525|delta/epsilon subdivisions,2WKX9@28221|Deltaproteobacteria,2MI4G@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Responsible for synthesis of pseudouridine from uracil	rluD	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
k141_4884_2	1121441.AUCX01000008_gene2232	2.31e-27	103.0	COG1324@1|root,COG1324@2|Bacteria,1N6TN@1224|Proteobacteria,42VE1@68525|delta/epsilon subdivisions,2WR7D@28221|Deltaproteobacteria,2MDG6@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	PFAM CutA1 divalent ion tolerance protein	cutA	-	-	ko:K03926	-	-	-	-	ko00000	-	-	-	CutA1
k141_755_1	1280001.BAOA01000049_gene1329	9.21e-23	108.0	COG4191@1|root,COG4191@2|Bacteria,1RG1X@1224|Proteobacteria,1RYNQ@1236|Gammaproteobacteria,1XU2S@135623|Vibrionales	135623|Vibrionales	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
k141_755_2	1304872.JAGC01000009_gene1444	6.11e-14	77.8	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,2M7UM@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	Two component, sigma54 specific, transcriptional regulator, Fis family	-	-	-	ko:K02481,ko:K07713	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
k141_755_3	1348635.BBJY01000004_gene2905	0.0	879.0	COG0554@1|root,COG0554@2|Bacteria,1MUP7@1224|Proteobacteria,1RMAF@1236|Gammaproteobacteria,1XUKJ@135623|Vibrionales	135623|Vibrionales	F	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate	glpK	GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615	2.7.1.30	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	-	R00847	RC00002,RC00017	ko00000,ko00001,ko01000,ko04147	-	-	-	FGGY_C,FGGY_N
k141_755_7	1348635.BBJY01000004_gene2909	9.07e-210	592.0	COG3075@1|root,COG3075@2|Bacteria,1MU3K@1224|Proteobacteria,1RP77@1236|Gammaproteobacteria,1XSPN@135623|Vibrionales	135623|Vibrionales	C	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor	glpB	GO:0003674,GO:0003824,GO:0004368,GO:0006091,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015980,GO:0016491,GO:0016614,GO:0016901,GO:0044237,GO:0045333,GO:0055114	1.1.5.3	ko:K00112	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	FAD_binding_2
k141_755_10	1502852.FG94_00169	2.29e-158	474.0	COG4625@1|root,COG4625@2|Bacteria,1R600@1224|Proteobacteria	1224|Proteobacteria	S	Rhamnogalacturonan lyase B, N-terminal	rhgB	-	4.2.2.23	ko:K18195	-	-	-	-	ko00000,ko01000	-	PL4	-	CBM-like,RhgB_N,fn3_3
k141_755_11	1236541.BALL01000022_gene2792	5.39e-221	622.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,1RQ36@1236|Gammaproteobacteria,2QAKM@267890|Shewanellaceae	1236|Gammaproteobacteria	L	Belongs to the DEAD box helicase family	dbpA	GO:0000027,GO:0000166,GO:0003674,GO:0003676,GO:0003723,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0006996,GO:0008026,GO:0008144,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0033677,GO:0034458,GO:0034459,GO:0034622,GO:0034641,GO:0035639,GO:0036094,GO:0042254,GO:0042255,GO:0042273,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0043531,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0065003,GO:0070035,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:0097367,GO:0140097,GO:0140098,GO:1901265,GO:1901360,GO:1901363	3.6.4.13	ko:K05591	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	DEAD,DbpA,Helicase_C
k141_755_12	1238450.VIBNISOn1_360037	1.08e-13	69.3	2C4GN@1|root,2ZHR0@2|Bacteria,1P917@1224|Proteobacteria,1STX2@1236|Gammaproteobacteria,1XY3H@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_755_16	314315.LCA_0231	5.51e-13	71.6	COG1846@1|root,COG1846@2|Bacteria,1VF51@1239|Firmicutes,4HM7R@91061|Bacilli,3F725@33958|Lactobacillaceae	91061|Bacilli	K	Transcriptional regulator, MarR family	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
k141_755_17	1333507.AUTQ01000208_gene3919	1.45e-35	146.0	COG0507@1|root,COG1112@1|root,COG0507@2|Bacteria,COG1112@2|Bacteria,1MWMG@1224|Proteobacteria,1RPEF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Superfamily I DNA and RNA helicases and helicase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_11,AAA_12,DUF559
k141_2127_1	945550.VISI1226_12981	2.04e-290	809.0	COG2274@1|root,COG2274@2|Bacteria,1R2T0@1224|Proteobacteria,1SBE1@1236|Gammaproteobacteria,1XTY1@135623|Vibrionales	135623|Vibrionales	V	COG2274 ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain	lapB	-	-	ko:K12541	ko02010,map02010	M00330	-	-	ko00000,ko00001,ko00002,ko02000,ko02044	3.A.1.109.3,3.A.1.109.4	-	-	ABC_membrane,ABC_tran,Peptidase_C39
k141_2127_3	674977.VMC_06350	4.72e-179	523.0	COG1315@1|root,COG1315@2|Bacteria,1R40D@1224|Proteobacteria,1RZ2U@1236|Gammaproteobacteria,1XT9Y@135623|Vibrionales	135623|Vibrionales	L	polymerase, most proteins contain PALM domain, HD hydrolase domain and Zn-ribbon domain	-	-	-	ko:K09749	-	-	-	-	ko00000	-	-	-	FapA
k141_4158_1	1278309.KB907102_gene202	1.83e-37	151.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1XI40@135619|Oceanospirillales	135619|Oceanospirillales	T	signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,NMT1,PAS,PAS_3,PAS_9
k141_756_1	1173029.JH980292_gene1295	1.88e-27	108.0	COG0598@1|root,COG0598@2|Bacteria,1G1AG@1117|Cyanobacteria,1H99G@1150|Oscillatoriales	1117|Cyanobacteria	P	Mediates influx of magnesium ions	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
k141_4550_1	1280706.AUJE01000062_gene1525	1.28e-10	62.8	COG1106@1|root,COG1106@2|Bacteria,1TSBY@1239|Firmicutes,4H955@909932|Negativicutes	909932|Negativicutes	S	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K06926	-	-	-	-	ko00000	-	-	-	AAA_21
k141_509_1	1219076.N646_4550	1.77e-220	615.0	COG0282@1|root,COG0282@2|Bacteria,1MW61@1224|Proteobacteria,1RMKB@1236|Gammaproteobacteria,1XT0N@135623|Vibrionales	135623|Vibrionales	F	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction	ackA2	GO:0003674,GO:0003824,GO:0006091,GO:0006113,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008776,GO:0009987,GO:0015980,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0044237,GO:0055114	2.7.2.1	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00315,R01353	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetate_kinase
k141_509_2	1188252.AJYK01000001_gene470	1.85e-06	48.1	COG1324@1|root,COG1324@2|Bacteria,1N6TN@1224|Proteobacteria,1SCFM@1236|Gammaproteobacteria,1XYEG@135623|Vibrionales	135623|Vibrionales	P	protein involved in tolerance to divalent cations	cutA	-	-	ko:K03926	-	-	-	-	ko00000	-	-	-	CutA1
k141_1136_1	658086.HMPREF0994_00324	1.72e-59	192.0	COG0671@1|root,COG0671@2|Bacteria,1V7SI@1239|Firmicutes,24FWW@186801|Clostridia,27M64@186928|unclassified Lachnospiraceae	186801|Clostridia	I	PAP2 superfamily	-	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
k141_4551_1	1121403.AUCV01000002_gene448	1.22e-10	67.8	COG4733@1|root,COG4932@1|root,COG5492@1|root,COG4733@2|Bacteria,COG4932@2|Bacteria,COG5492@2|Bacteria,1QW0V@1224|Proteobacteria,42U6C@68525|delta/epsilon subdivisions,2WQX8@28221|Deltaproteobacteria,2MN90@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,Big_3_2,DUF4215
k141_4552_1	83406.HDN1F_09770	1.18e-06	51.6	COG3842@1|root,COG3842@2|Bacteria,1RC3N@1224|Proteobacteria,1S2ZE@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	(ABC) transporter	-	-	3.6.3.29	ko:K02017	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.8	-	-	ABC_tran
k141_2129_1	675813.VIB_001757	2.21e-192	565.0	COG0457@1|root,COG0457@2|Bacteria,1RDRI@1224|Proteobacteria,1S3PB@1236|Gammaproteobacteria,1XTIH@135623|Vibrionales	135623|Vibrionales	S	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_12
k141_3157_1	1187848.AJYQ01000076_gene1685	4.14e-65	201.0	COG3120@1|root,COG3120@2|Bacteria,1RA57@1224|Proteobacteria,1S28S@1236|Gammaproteobacteria,1XWXZ@135623|Vibrionales	135623|Vibrionales	D	Required for spatial organization of the terminus region of the chromosome (Ter macrodomain) during the cell cycle. Prevents early segregation of duplicated Ter macrodomains during cell division. Binds specifically to matS, which is a 13 bp signature motif repeated within the Ter macrodomain	matP	-	-	ko:K09911	-	-	-	-	ko00000	-	-	-	MatP,MatP_C
k141_3157_2	1348635.BBJY01000005_gene3239	6.77e-242	682.0	COG1067@1|root,COG1067@2|Bacteria,1MWGB@1224|Proteobacteria,1RMPC@1236|Gammaproteobacteria,1XVTZ@135623|Vibrionales	135623|Vibrionales	O	Belongs to the peptidase S16 family	-	-	-	ko:K04770	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	AAA_32,Lon_C
k141_3157_3	55601.VANGNB10_cI1267c	2.16e-118	338.0	COG0764@1|root,COG0764@2|Bacteria,1MWV8@1224|Proteobacteria,1RP6W@1236|Gammaproteobacteria,1XSI6@135623|Vibrionales	135623|Vibrionales	I	Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length	fabA	GO:0003674,GO:0003824,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0008693,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0019171,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:0072330,GO:1901576	4.2.1.59,5.3.3.14	ko:K01716	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00083	R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07639	RC00831,RC01078,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FabA
k141_3157_4	55601.VANGNB10_cI1266	8.12e-31	108.0	COG3130@1|root,COG3130@2|Bacteria,1N761@1224|Proteobacteria,1SCIC@1236|Gammaproteobacteria,1XYV6@135623|Vibrionales	135623|Vibrionales	J	During stationary phase, converts 70S ribosomes to an inactive dimeric form (100S ribosomes)	rmf	-	-	ko:K03812	-	-	-	-	ko00000,ko03009	-	-	-	RMF
k141_779_1	526222.Desal_1465	1.58e-37	135.0	COG1304@1|root,COG1304@2|Bacteria,1MUEZ@1224|Proteobacteria,42N2F@68525|delta/epsilon subdivisions,2WKXN@28221|Deltaproteobacteria,2M878@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	PFAM FMN-dependent alpha-hydroxy acid dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_dh
k141_1465_1	55601.VANGNB10_cII0414c	4.01e-52	165.0	COG2963@1|root,COG2963@2|Bacteria,1RHBZ@1224|Proteobacteria,1S69Y@1236|Gammaproteobacteria,1XYNR@135623|Vibrionales	135623|Vibrionales	L	Transposase	-	-	-	ko:K07483	-	-	-	-	ko00000	-	-	-	HTH_Tnp_1
k141_1465_2	223926.28806779	3.98e-194	539.0	COG2801@1|root,COG2801@2|Bacteria,1MVXQ@1224|Proteobacteria,1RR4F@1236|Gammaproteobacteria,1Y2S7@135623|Vibrionales	135623|Vibrionales	L	COG2801 Transposase and inactivated derivatives	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve
k141_3843_2	55601.VANGNB10_cI0564	1.64e-263	728.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria,1XUBG@135623|Vibrionales	135623|Vibrionales	K	COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains	-	-	-	ko:K20919	ko05111,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_8,Sigma54_activat
k141_3843_3	243277.VC_0667	2.8e-199	558.0	COG0667@1|root,COG0667@2|Bacteria,1MV2Y@1224|Proteobacteria,1RNXH@1236|Gammaproteobacteria,1XTZ8@135623|Vibrionales	135623|Vibrionales	C	oxidoreductases (related to aryl-alcohol dehydrogenases)	tas	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
k141_3843_4	55601.VANGNB10_cI0567c	1.41e-122	353.0	COG3066@1|root,COG3066@2|Bacteria,1MVYX@1224|Proteobacteria,1RQVV@1236|Gammaproteobacteria,1XV3G@135623|Vibrionales	135623|Vibrionales	L	Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair	mutH	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360	-	ko:K03573	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutH
k141_3843_6	1348635.BBJY01000002_gene3509	1.46e-108	335.0	COG3605@1|root,COG3605@2|Bacteria,1QTTV@1224|Proteobacteria,1T1H2@1236|Gammaproteobacteria,1XSXI@135623|Vibrionales	135623|Vibrionales	T	Belongs to the PEP-utilizing enzyme family	ptsP	-	2.7.3.9	ko:K08484	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	-	-	-	GAF,PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C
k141_4564_2	1116375.VEJY3_08645	2.01e-101	299.0	COG2999@1|root,COG2999@2|Bacteria,1N9FA@1224|Proteobacteria,1RMFC@1236|Gammaproteobacteria,1XVZG@135623|Vibrionales	135623|Vibrionales	O	glutaredoxin 2	grxB	-	-	ko:K03675	-	-	-	-	ko00000,ko03110	-	-	-	GST_N_3,Glutaredoxin2_C
k141_4564_3	868595.Desca_0761	6.43e-166	476.0	COG1929@1|root,COG1929@2|Bacteria,1TPSI@1239|Firmicutes,249SH@186801|Clostridia,261CM@186807|Peptococcaceae	186801|Clostridia	G	Belongs to the glycerate kinase type-1 family	glxK	-	2.7.1.165	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	-	R08572	RC00002,RC00428	ko00000,ko00001,ko01000	-	-	-	Gly_kinase
k141_4564_4	365044.Pnap_2039	5.94e-58	193.0	COG0157@1|root,COG0157@2|Bacteria,1MW0C@1224|Proteobacteria,2VNEV@28216|Betaproteobacteria	28216|Betaproteobacteria	H	Belongs to the NadC ModD family	modD	-	-	ko:K03813	-	-	-	-	ko00000,ko01000	-	-	-	QRPTase_C,QRPTase_N
k141_4564_5	400668.Mmwyl1_2771	9.5e-149	430.0	COG1477@1|root,COG1477@2|Bacteria,1MW6K@1224|Proteobacteria,1RNMZ@1236|Gammaproteobacteria,1XNWT@135619|Oceanospirillales	135619|Oceanospirillales	H	ApbE family	-	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
k141_4564_6	701176.VIBRN418_07401	5.58e-55	179.0	COG5413@1|root,COG5413@2|Bacteria,1NA15@1224|Proteobacteria,1SCSY@1236|Gammaproteobacteria,1XXIV@135623|Vibrionales	135623|Vibrionales	S	Uncharacterized integral membrane protein (DUF2301)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2301
k141_4564_7	617140.AJZE01000091_gene4422	1.2e-119	347.0	COG1794@1|root,COG1794@2|Bacteria,1MV03@1224|Proteobacteria,1RMHT@1236|Gammaproteobacteria,1XSX2@135623|Vibrionales	135623|Vibrionales	M	Aspartate racemase	-	-	5.1.1.13	ko:K01779	ko00250,ko01054,map00250,map01054	-	R00491	RC00302	ko00000,ko00001,ko01000	-	-	-	Asp_Glu_race
k141_1466_1	1232453.BAIF02000040_gene3457	4.72e-56	196.0	COG3454@1|root,COG3454@2|Bacteria,1TRJ0@1239|Firmicutes,24AQ4@186801|Clostridia,26BPT@186813|unclassified Clostridiales	186801|Clostridia	P	Amidohydrolase family	phnM	-	3.6.1.63	ko:K06162	ko00440,map00440	-	R10186	RC00002	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1,Amidohydro_3
k141_3844_2	595494.Tola_1746	1.72e-170	489.0	COG1566@1|root,COG1566@2|Bacteria,1MU7I@1224|Proteobacteria,1RMAD@1236|Gammaproteobacteria,1Y5PB@135624|Aeromonadales	135624|Aeromonadales	V	HlyD membrane-fusion protein of T1SS	-	-	-	ko:K03543	-	M00701	-	-	ko00000,ko00002,ko02000	8.A.1.1	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
k141_780_1	439235.Dalk_3130	2.54e-24	102.0	COG0773@1|root,COG0773@2|Bacteria,1MV68@1224|Proteobacteria,42MMP@68525|delta/epsilon subdivisions,2WK50@28221|Deltaproteobacteria,2MIR1@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Belongs to the MurCDEF family	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
k141_780_2	1120973.AQXL01000130_gene1227	9.43e-43	156.0	COG0812@1|root,COG0812@2|Bacteria,1TP3W@1239|Firmicutes,4HAD8@91061|Bacilli,2785S@186823|Alicyclobacillaceae	91061|Bacilli	M	Cell wall formation	murB	GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008762,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0055114,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	-	FAD_binding_4,MurB_C
k141_530_1	1205908.AKXW01000150_gene2283	1.27e-66	209.0	COG0385@1|root,COG0385@2|Bacteria,1MUMM@1224|Proteobacteria,1RN2S@1236|Gammaproteobacteria,1XUIW@135623|Vibrionales	135623|Vibrionales	S	SBF-like CPA transporter family (DUF4137)	-	-	-	ko:K14347	-	-	-	-	ko00000,ko02000,ko04147	2.A.93.1	-	-	SBF_like
k141_530_2	1116375.VEJY3_19296	2.84e-149	425.0	COG1737@1|root,COG1737@2|Bacteria,1R6J5@1224|Proteobacteria,1RQ8A@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_6,SIS
k141_530_3	357804.Ping_2429	9.24e-143	406.0	COG1126@1|root,COG1126@2|Bacteria,1MU9Q@1224|Proteobacteria,1RMX1@1236|Gammaproteobacteria,2QHI0@267894|Psychromonadaceae	1236|Gammaproteobacteria	E	PFAM ABC transporter related	-	-	3.6.3.21	ko:K02028,ko:K02029,ko:K09972,ko:K16963	ko02010,map02010	M00232,M00236,M00586	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.3,3.A.1.3.17,3.A.1.3.18,3.A.1.3.7,3.A.1.3.8	-	-	ABC_tran
k141_530_4	1116375.VEJY3_19311	2.27e-135	385.0	COG0765@1|root,COG0765@2|Bacteria,1MVB6@1224|Proteobacteria,1RPGH@1236|Gammaproteobacteria,1XYGV@135623|Vibrionales	135623|Vibrionales	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02029	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	BPD_transp_1
k141_530_5	1116375.VEJY3_19306	4.85e-40	138.0	COG0765@1|root,COG0765@2|Bacteria,1MX2Y@1224|Proteobacteria,1RNQX@1236|Gammaproteobacteria,1XYU2@135623|Vibrionales	135623|Vibrionales	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02029	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	BPD_transp_1
k141_3845_1	1304885.AUEY01000004_gene909	1.2e-20	90.5	COG1250@1|root,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,42PBC@68525|delta/epsilon subdivisions,2WM7S@28221|Deltaproteobacteria,2MHZ4@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM 3-hydroxyacyl-CoA dehydrogenase domain protein	-	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
k141_3845_2	439235.Dalk_2641	5.26e-141	419.0	COG1960@1|root,COG1960@2|Bacteria,1MU20@1224|Proteobacteria,42Z3K@68525|delta/epsilon subdivisions,2WTSP@28221|Deltaproteobacteria,2MMNN@213118|Desulfobacterales	28221|Deltaproteobacteria	C	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_C,Acyl-CoA_dh_M,AcylCoA_DH_N
k141_783_1	1304885.AUEY01000004_gene1012	5.32e-32	126.0	COG3225@1|root,COG3225@2|Bacteria,1MY63@1224|Proteobacteria,42N95@68525|delta/epsilon subdivisions,2WJ0N@28221|Deltaproteobacteria,2MJFD@213118|Desulfobacterales	28221|Deltaproteobacteria	N	ABC-type uncharacterized transport system	-	-	-	-	-	-	-	-	-	-	-	-	ABC_transp_aux
k141_531_1	78398.KS43_22185	2.49e-23	97.8	COG4006@1|root,COG4006@2|Bacteria	2|Bacteria	S	CRISPR-associated protein, APE2256 family	VV2376	-	-	-	-	-	-	-	-	-	-	-	Cas_APE2256,DUF1887
k141_531_2	857087.Metme_2307	3.05e-98	312.0	COG1674@1|root,COG1674@2|Bacteria,1NGNP@1224|Proteobacteria,1STC8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	D	FtsK/SpoIIIE family	-	-	-	-	-	-	-	-	-	-	-	-	FtsK_SpoIIIE
k141_784_1	498211.CJA_2520	1.93e-57	202.0	COG1022@1|root,COG5184@1|root,COG5276@1|root,COG1022@2|Bacteria,COG5184@2|Bacteria,COG5276@2|Bacteria,1PG4J@1224|Proteobacteria,1RWXR@1236|Gammaproteobacteria,1FIEH@10|Cellvibrio	1236|Gammaproteobacteria	DZ	Regulator of chromosome condensation (RCC1) repeat	-	-	-	-	-	-	-	-	-	-	-	-	RCC1
k141_4566_1	1348635.BBJY01000016_gene3987	3.15e-96	288.0	COG3940@1|root,COG3940@2|Bacteria,1NKF0@1224|Proteobacteria,1RNIH@1236|Gammaproteobacteria,1XWTM@135623|Vibrionales	135623|Vibrionales	G	Glycosyl hydrolases family 43	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_43
k141_4566_2	1348635.BBJY01000016_gene3986	4.05e-262	727.0	COG2211@1|root,COG2211@2|Bacteria,1MVUM@1224|Proteobacteria,1RP5J@1236|Gammaproteobacteria,1XT0V@135623|Vibrionales	135623|Vibrionales	G	COG2211 Na melibiose symporter and related transporters	-	-	-	ko:K03292	-	-	-	-	ko00000	2.A.2	-	-	MFS_2
k141_4666_5	575788.VS_2813	2.22e-30	107.0	COG1841@1|root,COG1841@2|Bacteria,1N6ZE@1224|Proteobacteria,1SC8N@1236|Gammaproteobacteria,1XYYV@135623|Vibrionales	135623|Vibrionales	J	Ribosomal protein L30	rpmD	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02907	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L30
k141_4666_6	675814.VIC_004895	8.15e-107	309.0	COG0098@1|root,COG0098@2|Bacteria,1MUS4@1224|Proteobacteria,1RNEV@1236|Gammaproteobacteria,1XSIY@135623|Vibrionales	135623|Vibrionales	J	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body	rpsE	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02988	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S5,Ribosomal_S5_C
k141_4666_7	29495.EA26_19650	1.76e-68	208.0	COG0256@1|root,COG0256@2|Bacteria,1RGY7@1224|Proteobacteria,1S5V2@1236|Gammaproteobacteria,1XXCG@135623|Vibrionales	135623|Vibrionales	J	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance	rplR	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02881	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L18p
k141_4666_8	945543.VIBR0546_15072	3.64e-108	313.0	COG0097@1|root,COG0097@2|Bacteria,1R9YZ@1224|Proteobacteria,1S1Z1@1236|Gammaproteobacteria,1XSZ7@135623|Vibrionales	135623|Vibrionales	J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center	rplF	GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02933	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L6
k141_4666_9	223926.28805253	3.38e-79	236.0	COG0096@1|root,COG0096@2|Bacteria,1RDG3@1224|Proteobacteria,1S452@1236|Gammaproteobacteria,1XWW5@135623|Vibrionales	135623|Vibrionales	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit	rpsH	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02994	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S8
k141_2539_1	7668.SPU_010156-tr	4.53e-06	56.2	KOG0586@1|root,KOG0586@2759|Eukaryota	2759|Eukaryota	T	protein serine/threonine kinase activity	-	-	2.7.11.1	ko:K16311	ko04922,map04922	-	-	-	ko00000,ko00001,ko01000,ko01001,ko03036	-	-	-	Pkinase
k141_3252_1	373994.Riv7116_2494	6.29e-60	226.0	COG0642@1|root,COG0745@1|root,COG1196@1|root,COG1352@1|root,COG2201@1|root,COG3829@1|root,COG0745@2|Bacteria,COG1196@2|Bacteria,COG1352@2|Bacteria,COG2201@2|Bacteria,COG2205@2|Bacteria,COG3829@2|Bacteria,1G09B@1117|Cyanobacteria	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	2.1.1.80,3.1.1.61	ko:K03320,ko:K13924	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02000,ko02022,ko02035	1.A.11	-	-	CheB_methylest,CheR,CheR_N,GAF,HATPase_c,HisKA,PAS_10,PAS_4,Response_reg
k141_2540_1	1517681.HW45_16945	7.68e-16	80.9	COG1349@1|root,COG1349@2|Bacteria,1MUJG@1224|Proteobacteria,1RPS0@1236|Gammaproteobacteria,1XSYQ@135623|Vibrionales	135623|Vibrionales	K	COG1349 Transcriptional regulators of sugar metabolism	glpR	-	-	ko:K02444	-	-	-	-	ko00000,ko03000	-	-	-	DeoRC,HTH_DeoR
k141_2540_2	1524467.IV04_00060	5.55e-17	79.3	COG1995@1|root,COG1995@2|Bacteria,1MX5W@1224|Proteobacteria,1RNZV@1236|Gammaproteobacteria,401EU@613|Serratia	1236|Gammaproteobacteria	H	Belongs to the PdxA family	pdxA2	-	1.1.1.408,1.1.1.409	ko:K22024	-	-	-	-	ko00000,ko01000	-	-	-	PdxA
k141_876_5	1187848.AJYQ01000093_gene3474	1.43e-39	150.0	COG0577@1|root,COG0577@2|Bacteria,1MVCT@1224|Proteobacteria,1RNP1@1236|Gammaproteobacteria,1XUDJ@135623|Vibrionales	135623|Vibrionales	V	ABC-type antimicrobial peptide transport system, permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
k141_3981_2	1219065.VPR01S_09_00070	1.13e-214	600.0	COG0077@1|root,COG1605@1|root,COG0077@2|Bacteria,COG1605@2|Bacteria,1MU60@1224|Proteobacteria,1RNRD@1236|Gammaproteobacteria,1XT8C@135623|Vibrionales	135623|Vibrionales	E	chorismate mutase	pheA	-	4.2.1.51,5.4.99.5	ko:K14170	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R00691,R01373,R01715	RC00360,RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	CM_2,PDT
k141_3981_3	1348635.BBJY01000008_gene1701	4.64e-137	400.0	COG0687@1|root,COG0687@2|Bacteria,1R45E@1224|Proteobacteria,1RPF9@1236|Gammaproteobacteria,1XV8Q@135623|Vibrionales	135623|Vibrionales	E	COG0687 Spermidine putrescine-binding periplasmic protein	-	GO:0003674,GO:0003824,GO:0005215,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0015203,GO:0015399,GO:0015405,GO:0015417,GO:0015695,GO:0015696,GO:0015846,GO:0015847,GO:0015848,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0042623,GO:0042626,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:1902047	-	ko:K11069	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	SBP_bac_8
k141_3981_4	675815.VOA_003149	2.66e-90	289.0	COG5001@1|root,COG5001@2|Bacteria,1PRV9@1224|Proteobacteria,1RZHM@1236|Gammaproteobacteria,1XSCI@135623|Vibrionales	135623|Vibrionales	T	COG2199 FOG GGDEF domain	mbaA	GO:0007154,GO:0007165,GO:0008150,GO:0009987,GO:0023052,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007	3.1.4.52	ko:K20966	ko05111,map05111	-	-	-	ko00000,ko00001,ko01000	-	-	-	EAL,GGDEF
k141_3982_1	470145.BACCOP_00866	2.36e-46	165.0	COG0322@1|root,COG0322@2|Bacteria,4NE61@976|Bacteroidetes,2FNW9@200643|Bacteroidia,4AMYQ@815|Bacteroidaceae	976|Bacteroidetes	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:1902494,GO:1905347,GO:1905348,GO:1990391	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N
k141_877_1	1304885.AUEY01000036_gene2264	2.48e-18	86.7	2CNUX@1|root,32SHU@2|Bacteria,1REYT@1224|Proteobacteria,42R1S@68525|delta/epsilon subdivisions,2WMRC@28221|Deltaproteobacteria,2MJPR@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF2760)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2760
k141_2305_1	1304885.AUEY01000024_gene2722	1.89e-261	729.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,42N0C@68525|delta/epsilon subdivisions,2WJQQ@28221|Deltaproteobacteria,2MJ61@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Aldehyde dehydrogenase family	-	-	1.2.1.3,1.2.99.10	ko:K00128,ko:K22445	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
k141_2001_1	747365.Thena_0155	0.000135	49.7	COG0342@1|root,COG0342@2|Bacteria,1TQVT@1239|Firmicutes,247X8@186801|Clostridia,42F9I@68295|Thermoanaerobacterales	186801|Clostridia	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
k141_3983_1	36875.HQ29_00310	5.58e-22	97.1	COG3177@1|root,COG3177@2|Bacteria,4NFBY@976|Bacteroidetes,2FRIW@200643|Bacteroidia	976|Bacteroidetes	S	Fic/DOC family	-	-	-	-	-	-	-	-	-	-	-	-	Fic,Fic_N
k141_878_3	1232449.BAHV02000021_gene1035	4.26e-05	47.8	COG0235@1|root,COG0235@2|Bacteria	2|Bacteria	G	Class ii aldolase	-	-	4.1.2.17	ko:K01628	ko00051,ko01120,map00051,map01120	-	R02262	RC00603,RC00604	ko00000,ko00001,ko01000	-	-	-	Aldolase_II
k141_1559_1	999415.HMPREF9943_01345	1.32e-09	59.7	COG0642@1|root,COG2205@2|Bacteria,1V0S7@1239|Firmicutes,3VQ3Q@526524|Erysipelotrichia	526524|Erysipelotrichia	T	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,PAS_9,Response_reg
k141_1559_2	796620.VIBC2010_05134	1.87e-66	205.0	2AW2H@1|root,31MX9@2|Bacteria,1QJT1@1224|Proteobacteria,1THUA@1236|Gammaproteobacteria,1XXJU@135623|Vibrionales	135623|Vibrionales	S	Phage protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF3653
k141_1559_7	55601.VANGNB10_cII0441	2.71e-44	148.0	2DNV9@1|root,32ZB3@2|Bacteria,1MZGP@1224|Proteobacteria,1SE04@1236|Gammaproteobacteria,1XY7K@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_1559_9	382464.ABSI01000010_gene3259	1.18e-06	54.7	COG4675@1|root,COG4675@2|Bacteria	2|Bacteria	M	tail collar domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Collar,DUF859
k141_3265_1	641107.CDLVIII_5907	5.08e-62	203.0	COG2176@1|root,COG2176@2|Bacteria,1VAGI@1239|Firmicutes,24N73@186801|Clostridia,36M5M@31979|Clostridiaceae	186801|Clostridia	L	EXOIII	-	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	RNase_T
k141_3265_3	1117108.PAALTS15_05858	0.0	2261.0	COG5635@1|root,COG5635@2|Bacteria,1UK9Y@1239|Firmicutes	1239|Firmicutes	T	Nacht domain	-	-	-	-	-	-	-	-	-	-	-	-	NACHT
k141_3265_5	1230342.CTM_25848	8.71e-71	233.0	COG3677@1|root,COG3677@2|Bacteria,1TQNY@1239|Firmicutes,249FY@186801|Clostridia,36EGV@31979|Clostridiaceae	186801|Clostridia	L	Tn7-like transposition protein D	-	-	-	-	-	-	-	-	-	-	-	-	TniQ,TnsD
k141_4697_1	29495.EA26_17440	2.54e-145	421.0	28K8N@1|root,2Z9WC@2|Bacteria,1R5V8@1224|Proteobacteria,1S3I5@1236|Gammaproteobacteria,1XUIP@135623|Vibrionales	135623|Vibrionales	S	Protein of unknown function (DUF3549)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3549
k141_4697_2	223926.28807323	1.2e-32	116.0	2CHAX@1|root,32ZC9@2|Bacteria,1N6X2@1224|Proteobacteria,1SGKD@1236|Gammaproteobacteria,1XY31@135623|Vibrionales	135623|Vibrionales	S	Protein of unknown function (DUF3301)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3301
k141_4697_3	243277.VC_0884	7.52e-47	158.0	COG1670@1|root,COG1670@2|Bacteria,1RK72@1224|Proteobacteria,1S6IJ@1236|Gammaproteobacteria,1XX66@135623|Vibrionales	135623|Vibrionales	J	COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
k141_4697_4	345073.VC395_0898	1.97e-24	95.5	2CEIZ@1|root,33JKV@2|Bacteria,1NMVX@1224|Proteobacteria,1SIZS@1236|Gammaproteobacteria,1Y2BB@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_4697_5	1348635.BBJY01000020_gene2735	1.13e-63	197.0	COG1671@1|root,COG1671@2|Bacteria,1RCZA@1224|Proteobacteria,1S3QM@1236|Gammaproteobacteria,1XWZB@135623|Vibrionales	135623|Vibrionales	S	Belongs to the UPF0178 family	yaiI	-	-	ko:K09768	-	-	-	-	ko00000	-	-	-	DUF188
k141_3984_1	1121396.KB892924_gene637	5.61e-122	376.0	COG0826@1|root,COG0826@2|Bacteria,1MUQG@1224|Proteobacteria,42NTQ@68525|delta/epsilon subdivisions,2WITY@28221|Deltaproteobacteria,2MIFP@213118|Desulfobacterales	28221|Deltaproteobacteria	O	PFAM peptidase	-	-	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_U32
k141_4698_1	87626.PTD2_02401	7.13e-35	130.0	COG0621@1|root,COG0621@2|Bacteria,1MU7N@1224|Proteobacteria,1RN46@1236|Gammaproteobacteria,2PZZP@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	J	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12	rimO	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016782,GO:0018193,GO:0018197,GO:0018198,GO:0018339,GO:0019538,GO:0035596,GO:0035599,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050497,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:1901564	2.8.4.4	ko:K14441	-	-	R10652	RC00003,RC03217	ko00000,ko01000,ko03009	-	-	-	Radical_SAM,TRAM,UPF0004
k141_4698_2	945550.VISI1226_22175	1.72e-52	169.0	COG4103@1|root,COG4103@2|Bacteria,1N6YZ@1224|Proteobacteria,1SD1K@1236|Gammaproteobacteria,1XXJC@135623|Vibrionales	135623|Vibrionales	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	TerB
k141_879_1	1121434.AULY01000007_gene1239	2.21e-65	222.0	COG0620@1|root,COG0620@2|Bacteria,1MUI9@1224|Proteobacteria,42M8I@68525|delta/epsilon subdivisions,2WJGH@28221|Deltaproteobacteria,2M9Z8@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation	metE	-	2.1.1.14	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	M00017	R04405,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	Meth_synt_1,Meth_synt_2
k141_2885_2	342113.DM82_3708	3.07e-37	138.0	COG0583@1|root,COG0583@2|Bacteria,1MXRP@1224|Proteobacteria,2VK4M@28216|Betaproteobacteria,1K48J@119060|Burkholderiaceae	28216|Betaproteobacteria	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
k141_2885_3	404380.Gbem_3892	3.92e-76	249.0	COG0477@1|root,COG2814@2|Bacteria,1MW19@1224|Proteobacteria,42KZ4@68525|delta/epsilon subdivisions,2WKT2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	EGP	drug resistance transporter, Bcr CflA	-	-	-	ko:K07552	-	-	-	-	ko00000,ko02000	2.A.1.2	-	-	MFS_1
k141_2885_4	1283284.AZUK01000001_gene2456	1.09e-45	151.0	COG0634@1|root,COG0634@2|Bacteria	2|Bacteria	F	Belongs to the purine pyrimidine phosphoribosyltransferase family	hpt	-	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
k141_2002_1	617140.AJZE01000109_gene515	1.25e-150	434.0	COG1187@1|root,COG1187@2|Bacteria,1MXQE@1224|Proteobacteria,1RMC7@1236|Gammaproteobacteria,1XTHG@135623|Vibrionales	135623|Vibrionales	J	Belongs to the pseudouridine synthase RsuA family	rluF	-	5.4.99.21	ko:K06182	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
k141_2002_2	1348635.BBJY01000002_gene3409	7.72e-98	288.0	COG2840@1|root,COG2840@2|Bacteria,1RH34@1224|Proteobacteria,1S6B5@1236|Gammaproteobacteria,1XT93@135623|Vibrionales	135623|Vibrionales	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	Smr
k141_3266_2	485918.Cpin_2271	8.37e-08	57.4	COG2207@1|root,COG2207@2|Bacteria,4P70F@976|Bacteroidetes	2|Bacteria	K	SMART helix-turn-helix- domain containing protein, AraC type	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
k141_880_1	1304885.AUEY01000028_gene2790	1.66e-81	252.0	COG0150@1|root,COG0150@2|Bacteria,1MURG@1224|Proteobacteria,42KZT@68525|delta/epsilon subdivisions,2WIXY@28221|Deltaproteobacteria,2MHNK@213118|Desulfobacterales	28221|Deltaproteobacteria	F	PFAM AIR synthase related protein	purM	-	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1844	AIRS,AIRS_C
k141_2306_1	1121403.AUCV01000015_gene4724	2.23e-107	322.0	COG1914@1|root,COG1914@2|Bacteria,1MW6X@1224|Proteobacteria,42RRV@68525|delta/epsilon subdivisions,2WNKH@28221|Deltaproteobacteria,2MJB4@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Natural resistance-associated macrophage protein	-	-	-	-	-	-	-	-	-	-	-	-	Nramp
k141_2306_2	1348635.BBJY01000003_gene3696	2.63e-105	306.0	COG0386@1|root,COG0386@2|Bacteria,1RD1R@1224|Proteobacteria,1S425@1236|Gammaproteobacteria,1Y2NK@135623|Vibrionales	135623|Vibrionales	O	Glutathione peroxidase	gpo	-	1.11.1.9	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918	-	R00274,R07034,R07035	RC00011,RC00982	ko00000,ko00001,ko01000	-	-	-	GSHPx
k141_2306_3	945550.VISI1226_13953	2.8e-59	184.0	COG2920@1|root,COG2920@2|Bacteria,1RGVG@1224|Proteobacteria,1S5ZA@1236|Gammaproteobacteria,1XXBF@135623|Vibrionales	135623|Vibrionales	P	part of a sulfur-relay system	tusE	-	-	ko:K11179	ko04122,map04122	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	DsrC
k141_2306_4	1348635.BBJY01000005_gene3295	1.45e-30	110.0	COG1254@1|root,COG1254@2|Bacteria,1N6NU@1224|Proteobacteria,1SCPF@1236|Gammaproteobacteria,1XYDK@135623|Vibrionales	135623|Vibrionales	C	COG1254 Acylphosphatases	acyP	GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818	3.6.1.7	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	-	R00317,R01421,R01515	RC00043	ko00000,ko00001,ko01000	-	-	-	Acylphosphatase
k141_2306_5	945543.VIBR0546_00010	2.43e-71	226.0	COG1092@1|root,COG1092@2|Bacteria,1MUGB@1224|Proteobacteria,1RN7Z@1236|Gammaproteobacteria,1XTVB@135623|Vibrionales	135623|Vibrionales	J	Specifically methylates the cytosine at position 1962 (m5C1962) of 23S rRNA	rlmI	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
k141_4699_1	526222.Desal_2339	6.34e-77	251.0	COG1757@1|root,COG1757@2|Bacteria,1MY5C@1224|Proteobacteria,42P0P@68525|delta/epsilon subdivisions,2WN1R@28221|Deltaproteobacteria,2M9Y8@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	Na H antiporter	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_antiporter
k141_3985_2	1248232.BANQ01000182_gene198	1.78e-26	101.0	COG2963@1|root,COG2963@2|Bacteria,1NGD6@1224|Proteobacteria,1SGJ8@1236|Gammaproteobacteria,1XY4H@135623|Vibrionales	135623|Vibrionales	L	Transposase ISVa5 (IS66-family	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_2886_1	1265505.ATUG01000002_gene1959	4.64e-120	367.0	COG0243@1|root,COG3383@1|root,COG0243@2|Bacteria,COG3383@2|Bacteria,1MW3N@1224|Proteobacteria,43BJY@68525|delta/epsilon subdivisions,2WIWD@28221|Deltaproteobacteria,2MMY4@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Molydopterin dinucleotide binding domain	-	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0006464,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009326,GO:0009987,GO:0016043,GO:0016226,GO:0016491,GO:0016622,GO:0016903,GO:0018282,GO:0018289,GO:0018291,GO:0019538,GO:0022607,GO:0031163,GO:0032991,GO:0036211,GO:0042597,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0047111,GO:0051186,GO:0055114,GO:0071704,GO:0071840,GO:1901564,GO:1902494	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
k141_881_1	536233.CLO_0197	1.18e-06	53.9	COG1529@1|root,COG1529@2|Bacteria,1TP7U@1239|Firmicutes,248BV@186801|Clostridia,36DY8@31979|Clostridiaceae	186801|Clostridia	C	aldehyde oxidase and xanthine dehydrogenase, a b hammerhead	-	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
k141_881_2	1448139.AI20_14300	7.46e-10	61.6	COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,1RMCS@1236|Gammaproteobacteria,1Y5C8@135624|Aeromonadales	135624|Aeromonadales	M	Catalyzes the conversion of UDP-4-keto-arabinose (UDP- Ara4O) to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides	arnB	-	2.6.1.87	ko:K07806	ko00520,ko01503,ko02020,map00520,map01503,map02020	M00721,M00761	R07659	RC00006,RC01514	ko00000,ko00001,ko00002,ko01000,ko01005,ko01007	-	-	-	DegT_DnrJ_EryC1
k141_882_2	1232437.KL661988_gene14	3.97e-13	68.9	COG2089@1|root,COG2089@2|Bacteria,1MWG3@1224|Proteobacteria,42ME3@68525|delta/epsilon subdivisions,2WJXH@28221|Deltaproteobacteria,2MHVI@213118|Desulfobacterales	28221|Deltaproteobacteria	M	PFAM SAF domain	-	-	2.5.1.101,2.5.1.56	ko:K01654,ko:K18430	ko00520,ko01100,map00520,map01100	-	R01804,R04435,R10304	RC00159	ko00000,ko00001,ko01000	-	-	-	NeuB,SAF
k141_3689_1	1304284.L21TH_1234	1.59e-34	131.0	COG3359@1|root,COG3359@2|Bacteria,1U725@1239|Firmicutes,24A9V@186801|Clostridia,36DD2@31979|Clostridiaceae	186801|Clostridia	L	RNase_H superfamily	-	-	-	ko:K07502	-	-	-	-	ko00000	-	-	-	RNase_H_2
k141_3689_2	272563.CD630_07490	4.55e-194	570.0	COG0210@1|root,COG0210@2|Bacteria,1TPVG@1239|Firmicutes,2484I@186801|Clostridia,25QTG@186804|Peptostreptococcaceae	186801|Clostridia	L	DNA helicase	yjcD	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
k141_3689_3	1033737.CAEV01000097_gene1837	2.89e-59	199.0	COG0384@1|root,COG0384@2|Bacteria,1TPPX@1239|Firmicutes,247ZD@186801|Clostridia,36U61@31979|Clostridiaceae	186801|Clostridia	S	Phenazine biosynthesis-like protein	-	-	5.3.3.17	ko:K06998	ko00405,ko01130,ko02024,map00405,map01130,map02024	M00835	-	-	ko00000,ko00001,ko00002,ko01000	-	-	-	PhzC-PhzF
k141_3689_4	1391646.AVSU01000056_gene1286	6.61e-152	441.0	COG1104@1|root,COG1104@2|Bacteria,1TP21@1239|Firmicutes,24888@186801|Clostridia,25R11@186804|Peptostreptococcaceae	186801|Clostridia	E	Aminotransferase class-V	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
k141_3689_5	1121324.CLIT_5c00610	2.33e-176	503.0	COG0301@1|root,COG0301@2|Bacteria,1TPNW@1239|Firmicutes,247Y5@186801|Clostridia,25QNU@186804|Peptostreptococcaceae	186801|Clostridia	H	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS	thiI	-	2.8.1.4	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07461	-	ko00000,ko00001,ko01000,ko03016	-	-	-	THUMP,ThiI
k141_3689_6	1541959.KQ51_01091	3.82e-31	125.0	COG2199@1|root,COG3706@2|Bacteria,3WUMW@544448|Tenericutes	544448|Tenericutes	T	PAS fold	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS_9
k141_3689_7	1499689.CCNN01000006_gene563	5.6e-74	234.0	COG2897@1|root,COG2897@2|Bacteria,1TRYA@1239|Firmicutes,24GYI@186801|Clostridia,36I1B@31979|Clostridiaceae	186801|Clostridia	P	Rhodanese Homology Domain	-	-	2.8.1.1,2.8.1.2	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
k141_2307_2	1265505.ATUG01000001_gene3312	8.09e-137	394.0	COG4242@1|root,COG4242@2|Bacteria,1PR9J@1224|Proteobacteria,4303E@68525|delta/epsilon subdivisions,2WV4V@28221|Deltaproteobacteria	28221|Deltaproteobacteria	PQ	Belongs to the peptidase S51 family	-	-	3.4.15.6	ko:K13282	-	-	R09722	RC00064,RC00141	ko00000,ko01000,ko01002	-	-	-	Peptidase_S51
k141_2307_3	1265505.ATUG01000001_gene3313	2.35e-90	273.0	COG1446@1|root,COG1446@2|Bacteria,1MWFC@1224|Proteobacteria,42NRH@68525|delta/epsilon subdivisions,2WNIB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Peptidase T2, asparaginase 2	-	-	3.4.19.5	ko:K13051	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Asparaginase_2
k141_2308_1	1304878.AUGD01000009_gene6360	1.35e-77	249.0	COG1838@1|root,COG1951@1|root,COG1838@2|Bacteria,COG1951@2|Bacteria,1MUV9@1224|Proteobacteria,2TT46@28211|Alphaproteobacteria,3JTYW@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	Catalyzes the reversible hydration of fumarate to (S)- malate	fumA	GO:0003674,GO:0003824,GO:0004333,GO:0005488,GO:0005515,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016860,GO:0016862,GO:0016999,GO:0017144,GO:0019752,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0048037,GO:0050163,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0072350	4.2.1.2	ko:K01676	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumerase,Fumerase_C
k141_4700_1	1232437.KL662020_gene745	1.87e-171	489.0	COG1060@1|root,COG1060@2|Bacteria,1QN23@1224|Proteobacteria,42M6Z@68525|delta/epsilon subdivisions,2WJ4C@28221|Deltaproteobacteria,2MIGE@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate	mqnE	-	1.21.98.1,2.5.1.120,2.5.1.77	ko:K11779,ko:K11784,ko:K18285	ko00130,ko00680,ko01110,ko01120,map00130,map00680,map01110,map01120	M00378	R08588,R09396,R10667	RC00021,RC01381,RC02329,RC03002,RC03007,RC03234	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_3391	Radical_SAM
k141_4700_2	1304885.AUEY01000021_gene3442	3.53e-166	474.0	COG1060@1|root,COG1060@2|Bacteria,1MX50@1224|Proteobacteria,42M6U@68525|delta/epsilon subdivisions,2WJ6Y@28221|Deltaproteobacteria,2MJ4P@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnC	-	1.21.98.1	ko:K11784	ko00130,ko01110,map00130,map01110	-	R08588	RC02329	ko00000,ko00001,ko01000	-	-	-	Radical_SAM
k141_4700_3	247490.KSU1_D0753	1.4e-19	93.6	COG0402@1|root,COG0402@2|Bacteria,2IYVP@203682|Planctomycetes	203682|Planctomycetes	F	COG0402 Cytosine deaminase and related metal-dependent	-	-	3.5.4.40	ko:K20810	ko00130,ko01110,map00130,map01110	-	R10695	RC00477	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
k141_1287_2	236097.ADG881_553	8.17e-23	89.4	COG2963@1|root,COG2963@2|Bacteria,1MZ3D@1224|Proteobacteria,1S9EI@1236|Gammaproteobacteria,1XQ9X@135619|Oceanospirillales	135619|Oceanospirillales	L	L COG2801 Transposase and inactivated derivatives	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_Tnp_1
k141_1287_4	561230.PC1_0381	6.73e-66	207.0	COG1859@1|root,COG1859@2|Bacteria,1RD8B@1224|Proteobacteria,1S3U6@1236|Gammaproteobacteria,1MRXG@122277|Pectobacterium	1236|Gammaproteobacteria	J	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase	kptA	GO:0003674,GO:0003824,GO:0016740,GO:0016772	-	ko:K07559	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PTS_2-RNA
k141_1287_6	1205908.AKXW01000126_gene423	1.93e-221	616.0	COG5433@1|root,COG5433@2|Bacteria,1MXB5@1224|Proteobacteria,1RSAV@1236|Gammaproteobacteria,1XWBQ@135623|Vibrionales	135623|Vibrionales	L	DDE_Tnp_1-associated	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_assoc
k141_1287_9	1219077.VAZ01S_131_00040	8.46e-92	274.0	2C03A@1|root,2Z86B@2|Bacteria,1REIV@1224|Proteobacteria,1S4UW@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Domain of unknown function (DUF4291)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4291
k141_3481_1	1304885.AUEY01000025_gene2740	5.07e-73	226.0	COG3369@1|root,COG3592@1|root,COG3369@2|Bacteria,COG3592@2|Bacteria,1PMC1@1224|Proteobacteria,430UF@68525|delta/epsilon subdivisions,2WVWJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Iron-binding zinc finger CDGSH type	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_19,zf-CDGSH
k141_3481_2	933262.AXAM01000084_gene1050	2.47e-202	580.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,42MGZ@68525|delta/epsilon subdivisions,2WIY6@28221|Deltaproteobacteria,2MI9C@213118|Desulfobacterales	28221|Deltaproteobacteria	L	DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation	deaD	-	3.6.4.13	ko:K05592	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	DEAD,DbpA,Helicase_C
k141_2409_1	1051646.VITU9109_00560	1.76e-266	734.0	COG0582@1|root,COG0582@2|Bacteria,1N73Z@1224|Proteobacteria,1SEHI@1236|Gammaproteobacteria,1XTD7@135623|Vibrionales	135623|Vibrionales	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
k141_2409_2	232721.Ajs_2425	1.63e-71	226.0	2B275@1|root,31UQI@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF1837)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1837
k141_2409_3	715451.ambt_20455	3.74e-167	468.0	COG3293@1|root,COG3293@2|Bacteria,1P5HD@1224|Proteobacteria,1RSHY@1236|Gammaproteobacteria,466JD@72275|Alteromonadaceae	1236|Gammaproteobacteria	L	COG3293 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DUF4096
k141_414_1	1265505.ATUG01000002_gene1234	1.68e-48	172.0	COG1196@1|root,COG1196@2|Bacteria,1MVMQ@1224|Proteobacteria,42NF4@68525|delta/epsilon subdivisions,2WIMP@28221|Deltaproteobacteria,2MJAB@213118|Desulfobacterales	28221|Deltaproteobacteria	D	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_746_1	1265505.ATUG01000002_gene1540	4.73e-76	239.0	COG0583@1|root,COG0583@2|Bacteria,1MWUP@1224|Proteobacteria,42P24@68525|delta/epsilon subdivisions,2WJR2@28221|Deltaproteobacteria,2MIF4@213118|Desulfobacterales	28221|Deltaproteobacteria	K	LysR substrate binding domain	iciA	-	-	ko:K05596	-	-	-	-	ko00000,ko03000,ko03036	-	-	-	HTH_1,LysR_substrate
k141_2067_1	1304885.AUEY01000114_gene2924	8.36e-56	185.0	COG3221@1|root,COG3221@2|Bacteria,1NPBT@1224|Proteobacteria,42R8P@68525|delta/epsilon subdivisions,2WMU5@28221|Deltaproteobacteria,2MJQQ@213118|Desulfobacterales	28221|Deltaproteobacteria	P	ABC transporter, phosphonate, periplasmic substrate-binding protein	-	-	-	ko:K02044	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	Phosphonate-bd
k141_2067_2	1304885.AUEY01000114_gene2923	1.74e-65	210.0	COG3221@1|root,COG3221@2|Bacteria,1NPBT@1224|Proteobacteria,42R8P@68525|delta/epsilon subdivisions,2WMU5@28221|Deltaproteobacteria,2MJQQ@213118|Desulfobacterales	28221|Deltaproteobacteria	P	ABC transporter, phosphonate, periplasmic substrate-binding protein	-	-	-	ko:K02044	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	Phosphonate-bd
k141_747_1	1116375.VEJY3_17241	1.26e-98	301.0	COG2723@1|root,COG2723@2|Bacteria,1MWG6@1224|Proteobacteria,1RMM2@1236|Gammaproteobacteria,1XSV6@135623|Vibrionales	135623|Vibrionales	G	Belongs to the glycosyl hydrolase 1 family	bglA	-	3.2.1.86	ko:K01223	ko00010,ko00500,map00010,map00500	-	R00839,R05133,R05134	RC00049,RC00171,RC00714	ko00000,ko00001,ko01000	-	GT1	-	Glyco_hydro_1
k141_3109_2	1408422.JHYF01000014_gene264	2.11e-50	166.0	COG4508@1|root,COG4508@2|Bacteria	2|Bacteria	S	dUTPase	-	-	-	-	-	-	-	-	-	-	-	-	dUTPase_2
k141_748_1	177437.HRM2_47180	5.87e-100	327.0	COG0210@1|root,COG0514@1|root,COG0210@2|Bacteria,COG0514@2|Bacteria,1MVGG@1224|Proteobacteria,42MV3@68525|delta/epsilon subdivisions,2WJZB@28221|Deltaproteobacteria,2MHKM@213118|Desulfobacterales	28221|Deltaproteobacteria	L	TIGRFAM ATP-dependent DNA helicase, RecQ	-	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,HRDC,HTH_40,Helicase_C,RQC,RecQ_Zn_bind,UvrD-helicase,UvrD_C
k141_4808_1	439235.Dalk_2835	5.52e-61	202.0	COG0247@1|root,COG0247@2|Bacteria,1MUMH@1224|Proteobacteria,42M7J@68525|delta/epsilon subdivisions,2WK1N@28221|Deltaproteobacteria,2MMW5@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Cysteine-rich domain	-	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_8
k141_4808_2	827.JFJK01000021_gene108	6e-21	103.0	COG0277@1|root,COG0277@2|Bacteria,1MY08@1224|Proteobacteria,42Q28@68525|delta/epsilon subdivisions,2YNSA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	pfam fad	pchF	-	1.17.99.1	ko:K05797	ko00623,ko01100,ko01120,map00623,map01100,map01120	-	R02675,R11194	RC00769	ko00000,ko00001,ko01000	-	-	-	FAD_binding_4
k141_4808_3	1121396.KB893085_gene344	1.2e-94	312.0	COG1020@1|root,COG3321@1|root,COG1020@2|Bacteria,COG3321@2|Bacteria,1QK4F@1224|Proteobacteria,42Z5Y@68525|delta/epsilon subdivisions,2X8JI@28221|Deltaproteobacteria,2MMZD@213118|Desulfobacterales	28221|Deltaproteobacteria	Q	Condensation domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_1,Condensation,KAsynt_C_assoc,KR,Ketoacyl-synt_C,PP-binding,PS-DH,ketoacyl-synt
k141_3482_2	104623.Ser39006_00663	1.06e-141	409.0	COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,1RSC6@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	ABC transporter substrate-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	TctC
k141_3482_3	568768.CM001975_gene3257	6.05e-158	450.0	COG0329@1|root,COG0329@2|Bacteria,1MVWH@1224|Proteobacteria,1RP7A@1236|Gammaproteobacteria,2JEXY@204037|Dickeya	1236|Gammaproteobacteria	EM	Dihydrodipicolinate synthetase family	-	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
k141_3482_4	198628.Dda3937_00343	1.36e-43	154.0	COG0524@1|root,COG1349@1|root,COG0524@2|Bacteria,COG1349@2|Bacteria,1R52G@1224|Proteobacteria,1RN4W@1236|Gammaproteobacteria,2JEYR@204037|Dickeya	1236|Gammaproteobacteria	H	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway	-	-	-	-	-	-	-	-	-	-	-	-	HTH_DeoR,PfkB
k141_3484_1	999411.HMPREF1092_00511	8.01e-34	130.0	COG1473@1|root,COG1473@2|Bacteria,1TPD7@1239|Firmicutes,248AH@186801|Clostridia,36DRG@31979|Clostridiaceae	186801|Clostridia	E	amidohydrolase	cpsA	-	-	ko:K01436	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
k141_416_1	1348635.BBJY01000014_gene932	0.0	1451.0	COG0403@1|root,COG1003@1|root,COG0403@2|Bacteria,COG1003@2|Bacteria,1MUDP@1224|Proteobacteria,1RND3@1236|Gammaproteobacteria,1XU09@135623|Vibrionales	135623|Vibrionales	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvP	-	1.4.4.2	ko:K00281	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko00002,ko01000	-	-	-	GDC-P
k141_3485_1	342610.Patl_3904	1.01e-10	68.9	COG4773@1|root,COG4773@2|Bacteria,1QTXJ@1224|Proteobacteria	1224|Proteobacteria	P	COG1629 Outer membrane receptor proteins, mostly Fe transport	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,STN,TonB_dep_Rec
k141_2071_2	29495.EA26_04030	6.95e-173	486.0	COG0061@1|root,COG0061@2|Bacteria,1MUBC@1224|Proteobacteria,1RP84@1236|Gammaproteobacteria,1XTTS@135623|Vibrionales	135623|Vibrionales	F	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	nadK	-	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	NAD_kinase
k141_103_1	382464.ABSI01000006_gene809	2.12e-23	111.0	COG1538@1|root,COG1538@2|Bacteria,46V1S@74201|Verrucomicrobia,2IWGB@203494|Verrucomicrobiae	203494|Verrucomicrobiae	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
k141_104_1	1121441.AUCX01000005_gene1261	4.03e-92	285.0	COG0626@1|root,COG0626@2|Bacteria,1MU9E@1224|Proteobacteria,42Q4D@68525|delta/epsilon subdivisions,2WMEC@28221|Deltaproteobacteria,2MGRG@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	Cys/Met metabolism PLP-dependent enzyme	-	-	4.4.1.8	ko:K01760	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	M00017	R00782,R01286,R02408,R04941	RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303	ko00000,ko00001,ko00002,ko01000	-	-	-	Cys_Met_Meta_PP
k141_3487_1	1116375.VEJY3_02930	2.24e-16	81.3	COG4977@1|root,COG4977@2|Bacteria,1Q7DC@1224|Proteobacteria,1RQ1U@1236|Gammaproteobacteria,1XVE3@135623|Vibrionales	135623|Vibrionales	K	helix_turn_helix, arabinose operon control protein	-	-	-	ko:K02855	-	-	-	-	ko00000,ko03000	-	-	-	AraC_binding,HTH_18
k141_4809_19	720554.Clocl_1549	4.14e-55	206.0	COG0840@1|root,COG0840@2|Bacteria,1TP5A@1239|Firmicutes,247S3@186801|Clostridia,3WHE0@541000|Ruminococcaceae	186801|Clostridia	NT	methyl-accepting chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal
k141_4809_20	646529.Desaci_0840	6.76e-106	321.0	COG2201@1|root,COG2201@2|Bacteria,1TRHC@1239|Firmicutes,249FD@186801|Clostridia,26159@186807|Peptococcaceae	186801|Clostridia	NT	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR	cheB	-	3.1.1.61,3.5.1.44	ko:K03412	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,Response_reg
k141_4809_21	332101.JIBU02000004_gene164	1.56e-80	283.0	COG0642@1|root,COG2205@2|Bacteria,1TQMV@1239|Firmicutes,247SE@186801|Clostridia,36EKZ@31979|Clostridiaceae	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_9,Response_reg,sCache_3_3
k141_4809_22	203119.Cthe_0805	1.21e-55	177.0	COG0745@1|root,COG0745@2|Bacteria,1V774@1239|Firmicutes,24JS3@186801|Clostridia,3WJRP@541000|Ruminococcaceae	186801|Clostridia	T	cheY-homologous receiver domain	-	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
k141_4809_23	1391646.AVSU01000057_gene1251	3.19e-74	235.0	COG1307@1|root,COG1307@2|Bacteria,1TSKD@1239|Firmicutes	1239|Firmicutes	S	EDD domain protein, DegV family	yitS	-	-	-	-	-	-	-	-	-	-	-	DegV
k141_4809_24	536233.CLO_2217	7.08e-39	149.0	COG2206@1|root,COG2206@2|Bacteria,1TQIM@1239|Firmicutes,248S5@186801|Clostridia,36FJB@31979|Clostridiaceae	186801|Clostridia	T	SMART Metal-dependent phosphohydrolase, HD region	-	-	-	-	-	-	-	-	-	-	-	-	HD,HD_5
k141_4809_25	1121289.JHVL01000030_gene390	1.02e-110	329.0	COG0226@1|root,COG0226@2|Bacteria,1TQ5X@1239|Firmicutes,248QU@186801|Clostridia,36F61@31979|Clostridiaceae	186801|Clostridia	P	TIGRFAM phosphate binding protein	pstS	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
k141_4809_26	1121289.JHVL01000030_gene391	8.37e-125	366.0	COG0573@1|root,COG0573@2|Bacteria,1TSPP@1239|Firmicutes,249KQ@186801|Clostridia,36DTN@31979|Clostridiaceae	186801|Clostridia	P	probably responsible for the translocation of the substrate across the membrane	pstC	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
k141_4809_27	350688.Clos_0268	1.28e-106	317.0	COG0581@1|root,COG0581@2|Bacteria,1TP74@1239|Firmicutes,248C4@186801|Clostridia,36DCX@31979|Clostridiaceae	186801|Clostridia	P	Phosphate transport system permease protein PstA	pstA	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
k141_4809_28	35841.BT1A1_1115	7.36e-131	377.0	COG1117@1|root,COG1117@2|Bacteria,1TP1M@1239|Firmicutes,4HAB1@91061|Bacilli,1ZBQ5@1386|Bacillus	91061|Bacilli	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
k141_4809_29	1286171.EAL2_c16060	1.67e-74	231.0	COG0704@1|root,COG0704@2|Bacteria,1URN3@1239|Firmicutes,24FTM@186801|Clostridia,25WEB@186806|Eubacteriaceae	186801|Clostridia	P	Plays a role in the regulation of phosphate uptake	phoU	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009892,GO:0010563,GO:0010966,GO:0019220,GO:0019222,GO:0031323,GO:0031324,GO:0032879,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0042802,GO:0042803,GO:0043269,GO:0043271,GO:0044070,GO:0044424,GO:0044464,GO:0045936,GO:0046983,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051049,GO:0051051,GO:0051174,GO:0065007,GO:1903792,GO:1903795,GO:1903796,GO:1903959,GO:1903960,GO:2000185,GO:2000186	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
k141_4809_30	1304284.L21TH_2667	2.17e-240	670.0	COG0334@1|root,COG0334@2|Bacteria,1TP45@1239|Firmicutes,24960@186801|Clostridia,36EGU@31979|Clostridiaceae	186801|Clostridia	E	Belongs to the Glu Leu Phe Val dehydrogenases family	gdhA	-	1.4.1.3,1.4.1.4	ko:K00261,ko:K00262	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
k141_4809_31	1122947.FR7_2357	7.02e-40	148.0	COG3437@1|root,COG3437@2|Bacteria,1UYCB@1239|Firmicutes,4H2H0@909932|Negativicutes	909932|Negativicutes	T	SMART metal-dependent phosphohydrolase, HD region	-	-	-	-	-	-	-	-	-	-	-	-	DUF3369,HD,Response_reg
k141_4809_32	1121289.JHVL01000009_gene1417	6.94e-67	237.0	COG2984@1|root,COG4191@1|root,COG2984@2|Bacteria,COG4191@2|Bacteria,1UMAC@1239|Firmicutes,25GDF@186801|Clostridia	186801|Clostridia	T	ABC transporter substrate binding protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_4809_33	536232.CLM_0498	2.49e-129	379.0	COG0473@1|root,COG0473@2|Bacteria,1TPEM@1239|Firmicutes,24A63@186801|Clostridia,36E5F@31979|Clostridiaceae	186801|Clostridia	C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate	icd	-	1.1.1.41	ko:K00030	ko00020,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010	R00709	RC00114	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
k141_4809_34	1304284.L21TH_1190	4.54e-273	769.0	COG1048@1|root,COG1048@2|Bacteria,1VTMM@1239|Firmicutes,25HJM@186801|Clostridia,36FJS@31979|Clostridiaceae	186801|Clostridia	C	aconitate hydratase	acnA	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
k141_4809_35	1304284.L21TH_1191	9.9e-187	535.0	COG0119@1|root,COG0119@2|Bacteria,1TP4Y@1239|Firmicutes,2495J@186801|Clostridia,36FI9@31979|Clostridiaceae	186801|Clostridia	E	HMGL-like	-	GO:0003674,GO:0003824,GO:0016740,GO:0016746,GO:0036440,GO:0046912,GO:0050450	-	-	-	-	-	-	-	-	-	iHN637.CLJU_RS03250	HMGL-like
k141_4809_36	1345023.M467_11980	0.000189	50.8	COG0454@1|root,COG0454@2|Bacteria,COG0456@2|Bacteria,1VCMV@1239|Firmicutes,4HN6T@91061|Bacilli	91061|Bacilli	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
k141_4809_37	1121324.CLIT_23c01230	0.0	1316.0	COG0525@1|root,COG0525@2|Bacteria,1TPN4@1239|Firmicutes,248VC@186801|Clostridia,25QNK@186804|Peptostreptococcaceae	186801|Clostridia	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	-	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
k141_4809_39	1408823.AXUS01000016_gene1005	1.21e-150	441.0	COG0285@1|root,COG0285@2|Bacteria,1TPX5@1239|Firmicutes,247PC@186801|Clostridia,25QCF@186804|Peptostreptococcaceae	186801|Clostridia	H	Folylpolyglutamate synthase	folC	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_C,Mur_ligase_M
k141_4809_40	1415775.U729_2922	7.63e-32	113.0	2E3FD@1|root,32YE7@2|Bacteria,1VEE4@1239|Firmicutes,24QJ7@186801|Clostridia,36MNV@31979|Clostridiaceae	186801|Clostridia	S	TSCPD domain	-	-	-	-	-	-	-	-	-	-	-	-	TSCPD
k141_4809_41	941824.TCEL_00549	2.99e-26	105.0	COG3432@1|root,COG3432@2|Bacteria,1V75P@1239|Firmicutes,24JAZ@186801|Clostridia,36IRW@31979|Clostridiaceae	186801|Clostridia	K	Domain of unknown function (DUF4364)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4364
k141_4809_42	1121324.CLIT_23c01310	1.34e-226	646.0	COG3829@1|root,COG3829@2|Bacteria,1TP0E@1239|Firmicutes,247MB@186801|Clostridia,25S3J@186804|Peptostreptococcaceae	186801|Clostridia	KT	Bacterial regulatory protein, Fis family	prdR	-	-	-	-	-	-	-	-	-	-	-	CBS,HTH_8,PAS,PAS_4,PAS_9,Sigma54_activat
k141_4809_43	1121324.CLIT_23c01320	1.27e-194	550.0	COG4656@1|root,COG4656@2|Bacteria,1TPCC@1239|Firmicutes,24AN3@186801|Clostridia,25SKE@186804|Peptostreptococcaceae	186801|Clostridia	C	electron transport complex protein RnfC K03615	prdC	-	-	-	-	-	-	-	-	-	-	-	Complex1_51K,RnfC_N
k141_4809_44	1121324.CLIT_23c01330	0.0	929.0	COG0252@1|root,COG5275@1|root,COG0252@2|Bacteria,COG5275@2|Bacteria,1TQ9S@1239|Firmicutes,24A9Y@186801|Clostridia,25SZX@186804|Peptostreptococcaceae	186801|Clostridia	EJ	D-proline reductase	prdA	GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0046992,GO:0050002,GO:0050485,GO:0055114	1.21.4.1	ko:K10793	ko00330,map00330	-	R02825	RC00790	ko00000,ko00001,ko01000	-	-	-	Gly_reductase
k141_4809_45	1121324.CLIT_23c01340	4.26e-44	144.0	2BWPJ@1|root,32YWH@2|Bacteria,1VFE6@1239|Firmicutes,24QJI@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_4809_46	1121324.CLIT_23c01350	4.15e-96	284.0	COG1978@1|root,COG1978@2|Bacteria,1UYNY@1239|Firmicutes,24G4U@186801|Clostridia,25S4M@186804|Peptostreptococcaceae	186801|Clostridia	S	Glycine/sarcosine/betaine reductase selenoprotein B (GRDB)	prdB	-	1.21.4.1	ko:K10794	ko00330,map00330	-	R02825	RC00790	ko00000,ko00001,ko01000	-	-	-	GRDB
k141_4809_47	1121324.CLIT_23c01350	7.05e-39	135.0	COG1978@1|root,COG1978@2|Bacteria,1UYNY@1239|Firmicutes,24G4U@186801|Clostridia,25S4M@186804|Peptostreptococcaceae	186801|Clostridia	S	Glycine/sarcosine/betaine reductase selenoprotein B (GRDB)	prdB	-	1.21.4.1	ko:K10794	ko00330,map00330	-	R02825	RC00790	ko00000,ko00001,ko01000	-	-	-	GRDB
k141_4809_48	1121324.CLIT_23c01450	5.33e-105	311.0	COG5275@1|root,COG5275@2|Bacteria,1UZHN@1239|Firmicutes,24C77@186801|Clostridia,25SC9@186804|Peptostreptococcaceae	186801|Clostridia	S	Glycine/sarcosine/betaine reductase component B subunits	prdD	-	1.21.4.1	ko:K10793,ko:K10795	ko00330,map00330	-	R02825	RC00790	ko00000,ko00001,ko01000	-	-	-	Gly_reductase
k141_4809_49	1121324.CLIT_23c01370	2.55e-87	259.0	COG0252@1|root,COG0252@2|Bacteria,1V5HP@1239|Firmicutes,24GD5@186801|Clostridia	186801|Clostridia	EJ	reductase	prdE	-	-	ko:K10796	-	-	-	-	ko00000	-	-	-	Gly_reductase
k141_4809_50	1476973.JMMB01000007_gene2692	7.85e-195	545.0	COG3938@1|root,COG3938@2|Bacteria,1TQ61@1239|Firmicutes,2487S@186801|Clostridia,25SMF@186804|Peptostreptococcaceae	186801|Clostridia	E	Proline racemase	prdF	-	5.1.1.4	ko:K01777	ko00330,ko01100,map00330,map01100	-	R01255	RC00479	ko00000,ko00001,ko01000	-	-	-	Pro_racemase
k141_4809_51	1121324.CLIT_23c01390	4.42e-132	383.0	COG0730@1|root,COG0730@2|Bacteria,1TQ8H@1239|Firmicutes,24BA5@186801|Clostridia	186801|Clostridia	S	membrane transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	TauE
k141_1073_1	1348635.BBJY01000002_gene3473	1.36e-74	247.0	COG2199@1|root,COG3322@1|root,COG2199@2|Bacteria,COG3322@2|Bacteria,1QV91@1224|Proteobacteria,1T2AH@1236|Gammaproteobacteria,1XV0V@135623|Vibrionales	135623|Vibrionales	T	COG2199 FOG GGDEF domain	-	-	2.7.7.65	ko:K20958	ko05111,map05111	-	-	-	ko00000,ko00001,ko01000	-	-	-	CHASE4,GGDEF
k141_1073_2	675814.VIC_000684	7.87e-192	540.0	COG0389@1|root,COG0389@2|Bacteria,1MUUH@1224|Proteobacteria,1RMFM@1236|Gammaproteobacteria,1XTDB@135623|Vibrionales	135623|Vibrionales	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	dinB	-	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
k141_1073_3	1219076.N646_1459	1.35e-85	267.0	COG2199@1|root,COG2204@1|root,COG2204@2|Bacteria,COG3706@2|Bacteria,1MXBG@1224|Proteobacteria,1RNJA@1236|Gammaproteobacteria,1XSJA@135623|Vibrionales	135623|Vibrionales	T	COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Response_reg
k141_1431_1	1121912.AUHD01000013_gene994	9.47e-08	53.1	COG0693@1|root,COG0693@2|Bacteria,4NGII@976|Bacteroidetes,1HWTK@117743|Flavobacteriia	976|Bacteroidetes	I	intracellular protease amidase	-	-	-	-	-	-	-	-	-	-	-	-	DJ-1_PfpI
k141_1431_2	1517681.HW45_16860	7.44e-114	335.0	COG0561@1|root,COG0561@2|Bacteria,1R4WX@1224|Proteobacteria,1S3QA@1236|Gammaproteobacteria,1XVPQ@135623|Vibrionales	135623|Vibrionales	S	hydrolases of the HAD superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
k141_1431_3	1280001.BAOA01000022_gene585	4.01e-171	489.0	COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,1RM9E@1236|Gammaproteobacteria,1XSE0@135623|Vibrionales	135623|Vibrionales	P	Belongs to the ABC transporter superfamily	ugpC	GO:0003674,GO:0003824,GO:0005215,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015169,GO:0015399,GO:0015405,GO:0015430,GO:0015605,GO:0015711,GO:0015748,GO:0015794,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0034220,GO:0042623,GO:0042626,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0098656,GO:1901264,GO:1901505	3.6.3.20	ko:K05816	ko02010,map02010	M00198	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.1.3	-	-	ABC_tran,TOBE_2
k141_1431_4	1280001.BAOA01000022_gene586	1.49e-161	457.0	COG0395@1|root,COG0395@2|Bacteria,1MUWS@1224|Proteobacteria,1RMKG@1236|Gammaproteobacteria,1XVTC@135623|Vibrionales	135623|Vibrionales	P	probably responsible for the translocation of the substrate across the membrane	ugpE	-	-	ko:K05815	ko02010,map02010	M00198	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.3	-	-	BPD_transp_1
k141_1431_5	1219072.VHA01S_005_00670	5.31e-163	461.0	COG1175@1|root,COG1175@2|Bacteria,1MVAP@1224|Proteobacteria,1RNQF@1236|Gammaproteobacteria,1XSBT@135623|Vibrionales	135623|Vibrionales	P	permease	ugpA	-	-	ko:K05814	ko02010,map02010	M00198	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.3	-	-	BPD_transp_1
k141_1431_6	1517681.HW45_16880	4.52e-35	130.0	COG1653@1|root,COG1653@2|Bacteria,1MVMW@1224|Proteobacteria,1RRH3@1236|Gammaproteobacteria,1XV4I@135623|Vibrionales	135623|Vibrionales	G	ABC transporter	ugpB	-	-	ko:K05813	ko02010,map02010	M00198	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.3	-	-	SBP_bac_8
k141_456_1	82654.Pse7367_2142	5.66e-20	89.0	COG0125@1|root,COG0125@2|Bacteria,1G52G@1117|Cyanobacteria,1HAKD@1150|Oscillatoriales	1117|Cyanobacteria	F	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	tmk	GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylate_kin
k141_456_2	177437.HRM2_26760	7.49e-38	149.0	COG1452@1|root,COG1452@2|Bacteria,1MUJC@1224|Proteobacteria,42N34@68525|delta/epsilon subdivisions,2WJUD@28221|Deltaproteobacteria,2MI31@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane	lptD	-	-	ko:K04744	-	-	-	-	ko00000,ko02000	1.B.42.1	-	iAF987.Gmet_2474	OstA,OstA_2,OstA_C
k141_139_1	1304885.AUEY01000025_gene2758	0.0	922.0	COG1344@1|root,COG1344@2|Bacteria,1MV1N@1224|Proteobacteria,42MX8@68525|delta/epsilon subdivisions,2WJRC@28221|Deltaproteobacteria,2MISQ@213118|Desulfobacterales	28221|Deltaproteobacteria	N	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella	-	-	-	ko:K02406	ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flagellin_C,Flagellin_IN,Flagellin_N
k141_3131_1	1265505.ATUG01000001_gene4405	1.83e-97	304.0	COG2855@1|root,COG2855@2|Bacteria,1MVPE@1224|Proteobacteria,42NT6@68525|delta/epsilon subdivisions,2WJ9R@28221|Deltaproteobacteria,2MMP4@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Conserved hypothetical protein 698	-	-	-	-	-	-	-	-	-	-	-	-	Cons_hypoth698
k141_3131_2	1265505.ATUG01000001_gene4403	6.19e-50	179.0	COG4191@1|root,COG4191@2|Bacteria,1R6YZ@1224|Proteobacteria,42MXA@68525|delta/epsilon subdivisions,2WKQY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF3365,HATPase_c,HisKA,PAS_4
k141_140_1	1304885.AUEY01000089_gene128	9.02e-71	221.0	COG3271@1|root,COG3271@2|Bacteria,1R9HR@1224|Proteobacteria,43BBH@68525|delta/epsilon subdivisions,2WNUA@28221|Deltaproteobacteria,2MJXK@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Peptidase C39 family	-	-	-	ko:K06992	-	-	-	-	ko00000	-	-	-	Peptidase_C39
k141_1432_1	1121930.AQXG01000001_gene1459	8.47e-21	100.0	COG0708@1|root,COG2373@1|root,COG2911@1|root,COG2931@1|root,COG3210@1|root,COG5306@1|root,COG0708@2|Bacteria,COG2373@2|Bacteria,COG2911@2|Bacteria,COG2931@2|Bacteria,COG3210@2|Bacteria,COG5306@2|Bacteria,4NXBA@976|Bacteroidetes,1IZ5A@117747|Sphingobacteriia	976|Bacteroidetes	Q	alpha-L-arabinofuranosidase	-	-	-	-	-	-	-	-	-	-	-	-	Invasin_D3
k141_4810_1	1184267.A11Q_1364	1.81e-13	72.4	COG0482@1|root,COG0482@2|Bacteria,1MUT1@1224|Proteobacteria,42MZR@68525|delta/epsilon subdivisions,2MSYN@213481|Bdellovibrionales,2WK6B@28221|Deltaproteobacteria	213481|Bdellovibrionales	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
k141_4810_2	1121396.KB893056_gene2681	4.5e-120	364.0	COG0621@1|root,COG0621@2|Bacteria,1MUCS@1224|Proteobacteria,42MN1@68525|delta/epsilon subdivisions,2WJ1H@28221|Deltaproteobacteria,2MI7N@213118|Desulfobacterales	28221|Deltaproteobacteria	J	MiaB-like tRNA modifying enzyme	mtaB	-	2.8.4.5	ko:K18707	-	-	R10649	RC00003,RC03221	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,UPF0004
k141_4811_1	177437.HRM2_26640	7.8e-45	154.0	COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,42P5W@68525|delta/epsilon subdivisions,2WMA6@28221|Deltaproteobacteria,2MHP7@213118|Desulfobacterales	28221|Deltaproteobacteria	M	PFAM peptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
k141_457_1	1286171.EAL2_c03100	1.39e-113	340.0	COG5464@1|root,COG5464@2|Bacteria,1UGME@1239|Firmicutes,248B2@186801|Clostridia,25YE1@186806|Eubacteriaceae	186801|Clostridia	S	Putative transposase, YhgA-like	-	-	-	-	-	-	-	-	-	-	-	-	DUF4351,Transposase_31
k141_142_1	745411.B3C1_14767	7.67e-46	172.0	COG1629@1|root,COG4771@2|Bacteria,1MXAE@1224|Proteobacteria,1RWWH@1236|Gammaproteobacteria,1J9I1@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	P	TonB-dependent Receptor Plug Domain	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
k141_3132_1	228410.NE0123	5.86e-34	140.0	COG1353@1|root,COG1353@2|Bacteria,1NB2Y@1224|Proteobacteria,2VZCE@28216|Betaproteobacteria,373VE@32003|Nitrosomonadales	28216|Betaproteobacteria	S	TIGRFAM CRISPR-associated protein Csm1	-	-	-	ko:K07016	-	-	-	-	ko00000,ko02048	-	-	-	-
k141_5130_1	999141.GME_11867	1.58e-153	441.0	2CC6T@1|root,2ZA8Y@2|Bacteria,1RG72@1224|Proteobacteria,1SABM@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_5130_2	585.DR95_3491	4.37e-83	259.0	28KRI@1|root,2ZA91@2|Bacteria,1R9DY@1224|Proteobacteria,1S3WG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_5130_3	1005704.HMPREF9968_0633	9.76e-18	81.3	COG0454@1|root,COG0454@2|Bacteria,1VCXG@1239|Firmicutes,4HITJ@91061|Bacilli,1WPSC@1303|Streptococcus oralis	91061|Bacilli	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
k141_5130_4	672.VV93_v1c16710	8.14e-38	129.0	COG0346@1|root,COG0346@2|Bacteria,1N1T7@1224|Proteobacteria,1S8CN@1236|Gammaproteobacteria,1XXG3@135623|Vibrionales	135623|Vibrionales	E	Glyoxalase-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
k141_5130_5	1449065.JMLL01000010_gene1507	1.93e-35	136.0	COG0583@1|root,COG0583@2|Bacteria,1MWVB@1224|Proteobacteria,2TQXV@28211|Alphaproteobacteria,43HQ5@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
k141_5130_6	7668.SPU_028353-tr	7.57e-34	139.0	COG0604@1|root,KOG1198@2759|Eukaryota,38DDK@33154|Opisthokonta,3BIIZ@33208|Metazoa,3D1VQ@33213|Bilateria	33208|Metazoa	C	Reticulon-4-interacting protein 1	RTN4IP1	GO:0000003,GO:0000302,GO:0000303,GO:0000305,GO:0001654,GO:0001754,GO:0002376,GO:0003407,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005741,GO:0006950,GO:0006952,GO:0006955,GO:0006979,GO:0007275,GO:0007399,GO:0007417,GO:0007420,GO:0007423,GO:0008150,GO:0009314,GO:0009411,GO:0009416,GO:0009605,GO:0009607,GO:0009617,GO:0009628,GO:0009653,GO:0009790,GO:0009792,GO:0009887,GO:0009987,GO:0010035,GO:0010842,GO:0010975,GO:0016020,GO:0016319,GO:0019867,GO:0022008,GO:0030154,GO:0030182,GO:0031090,GO:0031344,GO:0031966,GO:0031967,GO:0031968,GO:0031975,GO:0032501,GO:0032502,GO:0032504,GO:0040008,GO:0040009,GO:0040010,GO:0040014,GO:0042221,GO:0042461,GO:0042462,GO:0042742,GO:0043010,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0045087,GO:0045595,GO:0045664,GO:0045927,GO:0046530,GO:0048468,GO:0048513,GO:0048518,GO:0048592,GO:0048593,GO:0048638,GO:0048646,GO:0048666,GO:0048699,GO:0048731,GO:0048856,GO:0048869,GO:0050767,GO:0050773,GO:0050789,GO:0050793,GO:0050794,GO:0050829,GO:0050896,GO:0051128,GO:0051239,GO:0051704,GO:0051707,GO:0051960,GO:0060041,GO:0060042,GO:0060284,GO:0060322,GO:0065007,GO:0070482,GO:0090596,GO:0098542,GO:0098588,GO:0098805,GO:0120035,GO:1901700,GO:2000026	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N_2
k141_5130_7	1348635.BBJY01000014_gene869	7.55e-51	168.0	2B0QJ@1|root,31MNT@2|Bacteria,1QJGF@1224|Proteobacteria,1THG6@1236|Gammaproteobacteria,1XVJQ@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_5130_8	1187848.AJYQ01000090_gene2771	3.15e-197	558.0	COG1257@1|root,COG1257@2|Bacteria,1Q6M1@1224|Proteobacteria,1RPEP@1236|Gammaproteobacteria,1XTS2@135623|Vibrionales	135623|Vibrionales	I	reductase	hmgA	-	1.1.1.34	ko:K00021	ko00900,ko01100,ko01110,ko01130,ko04152,ko04976,map00900,map01100,map01110,map01130,map04152,map04976	M00095	R02082	RC00004,RC00644	ko00000,ko00001,ko00002,ko01000	-	-	-	HMG-CoA_red
k141_5130_9	55601.VANGNB10_cII0694	4.65e-10	58.9	2AWP7@1|root,31NK4@2|Bacteria,1QKAT@1224|Proteobacteria,1TIEA@1236|Gammaproteobacteria,1XYZ3@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_4631_2	96561.Dole_0656	2.92e-14	68.2	COG1047@1|root,COG1047@2|Bacteria,1RD35@1224|Proteobacteria,42MCS@68525|delta/epsilon subdivisions,2WQGI@28221|Deltaproteobacteria,2MK26@213118|Desulfobacterales	28221|Deltaproteobacteria	O	peptidyl-prolyl cis-trans isomerase	-	-	5.2.1.8	ko:K01802	-	-	-	-	ko00000,ko01000	-	-	-	FKBP_C
k141_4946_1	936155.HFELIS_04120	0.000496	48.5	COG0470@1|root,COG0470@2|Bacteria,1R9U1@1224|Proteobacteria	1224|Proteobacteria	L	DNA polymerase III subunit delta'	holB	-	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNApol3-delta_C
k141_4946_2	439235.Dalk_0025	1.71e-90	278.0	COG1774@1|root,COG1774@2|Bacteria,1MZBX@1224|Proteobacteria,42NE3@68525|delta/epsilon subdivisions,2WK98@28221|Deltaproteobacteria,2MHSJ@213118|Desulfobacterales	28221|Deltaproteobacteria	S	PFAM PSP1 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PSP1
k141_2495_1	1116375.VEJY3_20481	3.81e-07	52.0	COG1115@1|root,COG1115@2|Bacteria,1MUI3@1224|Proteobacteria,1RMNF@1236|Gammaproteobacteria,1XZXD@135623|Vibrionales	135623|Vibrionales	E	Sodium:alanine symporter family	-	-	-	ko:K03310	-	-	-	-	ko00000	2.A.25	-	-	Na_Ala_symp
k141_2495_2	877418.ATWV01000010_gene119	4.5e-07	50.1	COG0251@1|root,COG0251@2|Bacteria	2|Bacteria	J	oxidation-reduction process	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
k141_2495_3	400668.Mmwyl1_1784	5.11e-82	248.0	COG1437@1|root,COG1437@2|Bacteria,1RBPX@1224|Proteobacteria,1S2EK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	F	Adenylate cyclase	cyaB	-	4.6.1.1	ko:K05873	ko00230,map00230	-	R00089,R00434	RC00295	ko00000,ko00001,ko01000	-	-	-	CYTH
k141_2495_4	998674.ATTE01000001_gene2883	1.62e-63	197.0	COG3791@1|root,COG3791@2|Bacteria,1N031@1224|Proteobacteria,1S8W1@1236|Gammaproteobacteria,462KW@72273|Thiotrichales	72273|Thiotrichales	S	Glutathione-dependent formaldehyde-activating enzyme	-	-	-	-	-	-	-	-	-	-	-	-	GFA
k141_2495_5	118005.AWNK01000006_gene1160	2.03e-68	215.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	MA20_05015	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_12,Methyltransf_23,Methyltransf_25,Methyltransf_31
k141_2495_6	717774.Marme_3998	1.11e-164	492.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,1XH50@135619|Oceanospirillales	135619|Oceanospirillales	NT	chemotaxis	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal,dCache_1
k141_2495_8	1209072.ALBT01000017_gene4189	0.0	1227.0	COG1472@1|root,COG1472@2|Bacteria,1MVIV@1224|Proteobacteria,1RMA0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	Belongs to the glycosyl hydrolase 3 family	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C,PA14
k141_2495_9	1209072.ALBT01000017_gene4188	9.06e-107	318.0	COG0657@1|root,COG0657@2|Bacteria,1R6QH@1224|Proteobacteria,1S036@1236|Gammaproteobacteria,1FFX0@10|Cellvibrio	1236|Gammaproteobacteria	I	Carboxylesterase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3
k141_2217_1	335659.S23_62030	2.22e-12	70.5	COG2203@1|root,COG5001@1|root,COG2203@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2TQS3@28211|Alphaproteobacteria,3JVPA@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF
k141_2217_2	1219065.VPR01S_04_01740	9.86e-187	536.0	COG1119@1|root,COG1119@2|Bacteria,1MVVM@1224|Proteobacteria,1RMXK@1236|Gammaproteobacteria,1XT5Q@135623|Vibrionales	135623|Vibrionales	P	COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA	-	-	-	ko:K05776	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	-	-	-	ABC_tran
k141_2217_3	243277.VC_2661	7.26e-180	508.0	COG1509@1|root,COG1509@2|Bacteria,1MUPJ@1224|Proteobacteria,1RM84@1236|Gammaproteobacteria,1XUU0@135623|Vibrionales	135623|Vibrionales	C	Lysine 2,3-aminomutase	yjeK	-	-	ko:K19810	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Fer4_12,Fer4_14,Radical_SAM
k141_2217_4	1280001.BAOA01000011_gene4270	1.04e-126	361.0	COG0231@1|root,COG0231@2|Bacteria,1MW2J@1224|Proteobacteria,1RPW7@1236|Gammaproteobacteria,1XSP6@135623|Vibrionales	135623|Vibrionales	J	Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-34 is required for alleviation	efp	GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
k141_3923_2	1304885.AUEY01000039_gene1531	1.58e-225	640.0	COG0446@1|root,COG0607@1|root,COG0446@2|Bacteria,COG0607@2|Bacteria,1NR3M@1224|Proteobacteria,42N3G@68525|delta/epsilon subdivisions,2WIS9@28221|Deltaproteobacteria,2MIFG@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Pyridine nucleotide-disulphide oxidoreductase, dimerisation	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Pyr_redox_dim,Rhodanese
k141_4633_1	1121403.AUCV01000057_gene3057	1.74e-130	393.0	28I4M@1|root,2Z883@2|Bacteria,1R6QB@1224|Proteobacteria,42Z98@68525|delta/epsilon subdivisions,2WTKQ@28221|Deltaproteobacteria,2MMTP@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_4947_1	571.MC52_30130	2.38e-15	75.5	COG3385@1|root,COG3385@2|Bacteria,1RBZF@1224|Proteobacteria,1S381@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
k141_4947_3	575788.VS_1135	1.4e-107	320.0	COG2515@1|root,COG2515@2|Bacteria,1R87T@1224|Proteobacteria,1RRB2@1236|Gammaproteobacteria,1XU3I@135623|Vibrionales	135623|Vibrionales	E	COG2515 1-aminocyclopropane-1-carboxylate deaminase	-	-	-	-	-	-	-	-	-	-	-	-	PALP
k141_2218_1	553385.JEMF01000018_gene905	1.34e-45	157.0	COG3155@1|root,COG3155@2|Bacteria,1MW2K@1224|Proteobacteria,1RMDJ@1236|Gammaproteobacteria,1XIDX@135619|Oceanospirillales	135619|Oceanospirillales	Q	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate	-	-	-	-	-	-	-	-	-	-	-	-	DJ-1_PfpI
k141_1518_1	347834.RHE_CH04102	1.75e-31	129.0	COG2199@1|root,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,2TQQM@28211|Alphaproteobacteria,4BDKF@82115|Rhizobiaceae	28211|Alphaproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
k141_1518_2	523794.Lebu_1155	2.89e-89	263.0	COG0698@1|root,COG0698@2|Bacteria	2|Bacteria	G	galactose-6-phosphate isomerase activity	rpiB	-	5.3.1.26,5.3.1.6	ko:K01808,ko:K01819	ko00030,ko00051,ko00052,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00052,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01056,R03240,R09030	RC00376,RC00434	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1604	LacAB_rpiB
k141_1518_4	1304872.JAGC01000009_gene564	7.23e-59	219.0	COG0643@1|root,COG0834@1|root,COG0643@2|Bacteria,COG0834@2|Bacteria,1N315@1224|Proteobacteria,43AUU@68525|delta/epsilon subdivisions,2X68Y@28221|Deltaproteobacteria,2MACZ@213115|Desulfovibrionales	28221|Deltaproteobacteria	ENT	Bacterial periplasmic substrate-binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,SBP_bac_3
k141_1518_5	675815.VOA_000184	1.84e-97	295.0	COG1793@1|root,COG1793@2|Bacteria,1MUW3@1224|Proteobacteria,1S2JP@1236|Gammaproteobacteria,1XTX8@135623|Vibrionales	135623|Vibrionales	L	DNA ligase	-	-	6.5.1.1,6.5.1.6,6.5.1.7	ko:K10747	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00381,R00382,R10822,R10823	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	DNA_ligase_A_M,DNA_ligase_OB_2
k141_1518_6	326297.Sama_0729	1.2e-15	76.6	COG3263@1|root,COG3263@2|Bacteria,1MVKV@1224|Proteobacteria,1RMCA@1236|Gammaproteobacteria,2QB2X@267890|Shewanellaceae	1236|Gammaproteobacteria	P	K( ) H( ) antiporter that extrudes potassium in exchange for external protons and maintains the internal concentration of potassium under toxic levels	nhaP2	GO:0003674,GO:0005215,GO:0005451,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0006884,GO:0008150,GO:0008324,GO:0008361,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015079,GO:0015291,GO:0015297,GO:0015298,GO:0015299,GO:0015318,GO:0015386,GO:0015491,GO:0015672,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022804,GO:0022821,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0031226,GO:0032535,GO:0034220,GO:0042592,GO:0044425,GO:0044459,GO:0044464,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0065007,GO:0065008,GO:0071804,GO:0071805,GO:0071840,GO:0071944,GO:0090066,GO:0098655,GO:0098660,GO:0098662,GO:0099516,GO:1902600	-	ko:K11105	-	-	-	-	ko00000,ko02000	2.A.36.6	-	-	CorC_HlyC,Na_H_Exchanger,TrkA_C
k141_4634_1	1265505.ATUG01000002_gene2814	1.29e-23	95.1	COG0688@1|root,COG0688@2|Bacteria,1MW45@1224|Proteobacteria,42QDS@68525|delta/epsilon subdivisions,2WMQ3@28221|Deltaproteobacteria,2MJQ8@213118|Desulfobacterales	28221|Deltaproteobacteria	I	Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)	psd	-	4.1.1.65	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	M00093	R02055	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	PS_Dcarbxylase
k141_4634_2	1123371.ATXH01000012_gene1441	5.69e-64	206.0	COG1183@1|root,COG1183@2|Bacteria,2GHN6@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	I	CDP-alcohol phosphatidyltransferase	-	-	2.7.8.8	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	M00093	R01800	RC00002,RC00017,RC02795	ko00000,ko00001,ko00002,ko01000	-	-	-	CDP-OH_P_transf
k141_270_1	643562.Daes_0635	5.7e-126	372.0	COG1473@1|root,COG1473@2|Bacteria,1MUIV@1224|Proteobacteria,42PC8@68525|delta/epsilon subdivisions,2X5FY@28221|Deltaproteobacteria,2MGQB@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	PFAM Peptidase M20	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
k141_270_2	1121456.ATVA01000018_gene374	3.71e-69	212.0	2DC0W@1|root,2ZCA7@2|Bacteria,1R3B5@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_270_3	1121451.DESAM_23193	5.17e-140	401.0	arCOG09719@1|root,2Z7NA@2|Bacteria,1R5HX@1224|Proteobacteria,42ZSJ@68525|delta/epsilon subdivisions,2X02P@28221|Deltaproteobacteria,2MA24@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF3100)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3100
k141_270_4	349521.HCH_04810	1.13e-23	98.6	COG0834@1|root,COG0834@2|Bacteria,1RCP2@1224|Proteobacteria,1S2BF@1236|Gammaproteobacteria,1XPNQ@135619|Oceanospirillales	135619|Oceanospirillales	ET	ABC-type amino acid transport signal transduction systems, periplasmic component domain	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
k141_4949_1	1304885.AUEY01000006_gene745	2.29e-12	72.4	COG0642@1|root,COG5002@1|root,COG2205@2|Bacteria,COG5002@2|Bacteria,1NRP8@1224|Proteobacteria,42M0Y@68525|delta/epsilon subdivisions,2WIR4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,GAF,HATPase_c,HisKA,MASE1,PAS_3,Response_reg
k141_2220_1	243277.VC_A0116	1.39e-135	413.0	COG0542@1|root,COG0542@2|Bacteria,1MVBH@1224|Proteobacteria,1RMZH@1236|Gammaproteobacteria,1XTVD@135623|Vibrionales	135623|Vibrionales	O	Belongs to the ClpA ClpB family	-	-	-	ko:K11907	ko02025,ko03070,map02025,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
k141_4636_1	690850.Desaf_0534	1.21e-102	302.0	COG0655@1|root,COG0655@2|Bacteria,1NTW6@1224|Proteobacteria,42Y8M@68525|delta/epsilon subdivisions,2WUIU@28221|Deltaproteobacteria,2MG3R@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
k141_2497_2	177437.HRM2_45370	7.03e-97	290.0	COG0745@1|root,COG0745@2|Bacteria,1MY3D@1224|Proteobacteria,42MG4@68525|delta/epsilon subdivisions,2X5VM@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	Two component transcriptional regulator, winged helix family	-	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
k141_1907_1	1238450.VIBNISOn1_1500001	8.26e-145	412.0	COG0175@1|root,COG0175@2|Bacteria,1MXUR@1224|Proteobacteria,1RNC5@1236|Gammaproteobacteria,1XTU8@135623|Vibrionales	135623|Vibrionales	EH	Belongs to the PAPS reductase family. CysH subfamily	cysH	GO:0003674,GO:0003824,GO:0004604,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006790,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016667,GO:0016671,GO:0044237,GO:0044424,GO:0044464,GO:0055114	1.8.4.10,1.8.4.8	ko:K00390	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00176	R02021	RC00007,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	-	PAPS_reduct
k141_1907_2	29495.EA26_02525	0.0	1000.0	COG0155@1|root,COG0155@2|Bacteria,1MVVB@1224|Proteobacteria,1RMFH@1236|Gammaproteobacteria,1XTQM@135623|Vibrionales	135623|Vibrionales	H	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate	cysI	GO:0003674,GO:0003824,GO:0004783,GO:0005575,GO:0005622,GO:0005623,GO:0006790,GO:0008150,GO:0008152,GO:0009337,GO:0009987,GO:0016002,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016673,GO:0019419,GO:0032991,GO:0044237,GO:0044424,GO:0044464,GO:0050311,GO:0055114	1.8.1.2	ko:K00381	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00176	R00858	RC00065	ko00000,ko00001,ko00002,ko01000	-	-	-	NIR_SIR,NIR_SIR_ferr
k141_1907_3	223926.28807732	7.29e-278	779.0	COG0369@1|root,COG0369@2|Bacteria,1QUAH@1224|Proteobacteria,1T1RJ@1236|Gammaproteobacteria,1XT6J@135623|Vibrionales	135623|Vibrionales	P	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component	cysJ	-	1.8.1.2	ko:K00380	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00176	R00858	RC00065	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_1,Flavodoxin_1,NAD_binding_1
k141_1907_4	298386.PBPRA3322	3.45e-16	73.2	2C2GZ@1|root,2ZHSS@2|Bacteria,1P942@1224|Proteobacteria,1STTI@1236|Gammaproteobacteria,1XYB8@135623|Vibrionales	135623|Vibrionales	-	-	VV2968	-	-	-	-	-	-	-	-	-	-	-	-
k141_1907_6	796620.VIBC2010_19105	8.82e-205	570.0	COG0042@1|root,COG0042@2|Bacteria,1MUY1@1224|Proteobacteria,1RN28@1236|Gammaproteobacteria,1XUYB@135623|Vibrionales	135623|Vibrionales	J	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs	dusA	-	-	ko:K05539	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Dus
k141_1907_7	1191299.AJYX01000042_gene2402	1.04e-13	70.5	COG0582@1|root,COG0582@2|Bacteria,1NWGS@1224|Proteobacteria,1S4PB@1236|Gammaproteobacteria,1XVNY@135623|Vibrionales	135623|Vibrionales	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
k141_1907_8	945550.VISI1226_20660	4.29e-48	163.0	COG0582@1|root,COG0582@2|Bacteria,1NWGS@1224|Proteobacteria,1S4PB@1236|Gammaproteobacteria,1XVNY@135623|Vibrionales	135623|Vibrionales	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
k141_1907_9	945543.VIBR0546_12267	7.92e-25	98.6	2AW90@1|root,31N4B@2|Bacteria,1QJVS@1224|Proteobacteria,1THXD@1236|Gammaproteobacteria,1XXT9@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_1907_10	1056512.D515_00136	1.43e-126	391.0	COG1388@1|root,COG4104@1|root,COG1388@2|Bacteria,COG4104@2|Bacteria,1MXSH@1224|Proteobacteria,1S2D5@1236|Gammaproteobacteria,1Y3AG@135623|Vibrionales	135623|Vibrionales	M	S-type Pyocin	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_1907_11	945550.VISI1226_20645	4.21e-18	76.3	2AWX8@1|root,31NUU@2|Bacteria,1QKIH@1224|Proteobacteria,1TINR@1236|Gammaproteobacteria,1XZDU@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_1907_12	1122194.AUHU01000003_gene2280	6.83e-216	625.0	COG2730@1|root,COG2730@2|Bacteria,1PY25@1224|Proteobacteria,1SYWJ@1236|Gammaproteobacteria,4666R@72275|Alteromonadaceae	1236|Gammaproteobacteria	G	CBD_II	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	CBM_10,CBM_2,CBM_5_12_2,Cellulase,Glyco_hydro_11
k141_1907_13	243277.VC_0378	8.88e-73	222.0	COG0735@1|root,COG0735@2|Bacteria,1MZIW@1224|Proteobacteria,1S5ZI@1236|Gammaproteobacteria,1XWW0@135623|Vibrionales	135623|Vibrionales	K	Belongs to the Fur family	zur	-	-	ko:K09823	ko02024,map02024	-	-	-	ko00000,ko00001,ko03000	-	-	-	FUR
k141_1907_14	1238450.VIBNISOn1_1500009	9.84e-99	287.0	COG1406@1|root,COG1406@2|Bacteria,1RATZ@1224|Proteobacteria,1S22M@1236|Gammaproteobacteria,1XTSB@135623|Vibrionales	135623|Vibrionales	N	inhibitor of MCP methylation, homolog of CheC	cheX	-	-	ko:K03409	ko02030,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheX
k141_1907_15	1348635.BBJY01000032_gene53	0.0	900.0	COG0166@1|root,COG0166@2|Bacteria,1MUFP@1224|Proteobacteria,1RNIT@1236|Gammaproteobacteria,1XT97@135623|Vibrionales	135623|Vibrionales	G	Belongs to the GPI family	pgi	GO:0003674,GO:0003824,GO:0004347,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576	5.3.1.9	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI
k141_1907_16	1219065.VPR01S_31_00110	2.25e-69	213.0	COG0432@1|root,COG0432@2|Bacteria,1RH13@1224|Proteobacteria,1S3VP@1236|Gammaproteobacteria,1XWZM@135623|Vibrionales	135623|Vibrionales	S	Uncharacterised protein family UPF0047	-	-	-	-	-	-	-	-	-	-	-	-	UPF0047
k141_1907_18	345073.VC395_0413	6.35e-90	274.0	COG3137@1|root,COG3137@2|Bacteria,1N9KB@1224|Proteobacteria,1THEB@1236|Gammaproteobacteria,1XUUB@135623|Vibrionales	135623|Vibrionales	M	salt-induced outer membrane protein	VP2736	-	-	ko:K07283	-	-	-	-	ko00000	-	-	-	DUF481
k141_1907_19	223926.28807747	1.33e-83	249.0	COG0359@1|root,COG0359@2|Bacteria,1RD0R@1224|Proteobacteria,1S3WS@1236|Gammaproteobacteria,1XU9I@135623|Vibrionales	135623|Vibrionales	J	Binds to the 23S rRNA	rplI	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02939	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L9_C,Ribosomal_L9_N
k141_1907_20	1280001.BAOA01000035_gene2432	7.61e-46	147.0	COG0238@1|root,COG0238@2|Bacteria,1MZ8U@1224|Proteobacteria,1S8R8@1236|Gammaproteobacteria,1XY1I@135623|Vibrionales	135623|Vibrionales	J	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit	rpsR	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02963	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S18
k141_1907_21	345073.VC395_0409	5.21e-74	223.0	COG0360@1|root,COG0360@2|Bacteria,1RH82@1224|Proteobacteria,1S5VU@1236|Gammaproteobacteria,1XWUY@135623|Vibrionales	135623|Vibrionales	J	Binds together with S18 to 16S ribosomal RNA	rpsF	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02990	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S6
k141_2221_1	1122212.AULO01000007_gene2151	7.26e-148	426.0	COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,1RQ7S@1236|Gammaproteobacteria,1XN6S@135619|Oceanospirillales	135619|Oceanospirillales	M	DegT/DnrJ/EryC1/StrS aminotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
k141_2221_2	211586.SO_3186	4.89e-31	117.0	COG1209@1|root,COG1209@2|Bacteria,1MU0X@1224|Proteobacteria,1RMTR@1236|Gammaproteobacteria,2QAWW@267890|Shewanellaceae	1236|Gammaproteobacteria	H	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis	rfbA	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
k141_558_2	1517681.HW45_14480	0.0	1242.0	COG0296@1|root,COG0296@2|Bacteria,1QTVN@1224|Proteobacteria,1RQSK@1236|Gammaproteobacteria,1XU7M@135623|Vibrionales	135623|Vibrionales	G	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position	glgB	GO:0000271,GO:0003674,GO:0003824,GO:0003844,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0055114,GO:0071704,GO:1901576	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_48
k141_558_3	1348635.BBJY01000001_gene2523	0.0	921.0	COG1640@1|root,COG1640@2|Bacteria,1QTVJ@1224|Proteobacteria,1RMJW@1236|Gammaproteobacteria,1XTQ7@135623|Vibrionales	135623|Vibrionales	G	4-alpha-glucanotransferase	malQ	-	2.4.1.25	ko:K00705	ko00500,ko01100,map00500,map01100	-	R05196	RC00049	ko00000,ko00001,ko01000	-	GH77	-	Glyco_hydro_77
k141_1519_1	55601.VANGNB10_cI1240c	1.19e-204	569.0	COG0834@1|root,COG0834@2|Bacteria,1MV5D@1224|Proteobacteria,1RNJJ@1236|Gammaproteobacteria,1XSSI@135623|Vibrionales	135623|Vibrionales	ET	COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain	aapJ	-	-	ko:K09969	ko02010,map02010	M00232	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3.18,3.A.1.3.7,3.A.1.3.8	-	-	SBP_bac_3
k141_1519_2	1348635.BBJY01000005_gene3290	1.15e-213	598.0	COG4597@1|root,COG4597@2|Bacteria,1MV0S@1224|Proteobacteria,1RN6V@1236|Gammaproteobacteria,1XSEY@135623|Vibrionales	135623|Vibrionales	P	COG4597 ABC-type amino acid transport system, permease component	aapQ	-	-	ko:K09970	ko02010,map02010	M00232	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3.18,3.A.1.3.7,3.A.1.3.8	-	-	BPD_transp_1
k141_4637_1	177437.HRM2_27970	5.04e-15	75.5	COG1219@1|root,COG1219@2|Bacteria,1MWIZ@1224|Proteobacteria,42N1Z@68525|delta/epsilon subdivisions,2WJUS@28221|Deltaproteobacteria,2MHMD@213118|Desulfobacterales	28221|Deltaproteobacteria	O	Belongs to the ClpX chaperone family	-	-	-	-	-	-	-	-	-	-	-	-	AAA_2,ClpB_D2-small
k141_4637_2	177437.HRM2_29540	4.09e-51	171.0	COG1309@1|root,COG1309@2|Bacteria,1RK62@1224|Proteobacteria,42SVK@68525|delta/epsilon subdivisions,2WP42@28221|Deltaproteobacteria,2MKC3@213118|Desulfobacterales	28221|Deltaproteobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
k141_1520_1	177437.HRM2_47510	1.04e-74	238.0	COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,42Q6B@68525|delta/epsilon subdivisions,2WMJ7@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	PFAM TRAP C4-dicarboxylate transport system permease DctM subunit	-	-	-	ko:K21393	-	-	-	-	ko00000,ko02000	2.A.56.1	-	-	DctM
k141_2222_1	1265505.ATUG01000003_gene681	6.93e-132	391.0	COG1228@1|root,COG1228@2|Bacteria,1MVAF@1224|Proteobacteria,42MKS@68525|delta/epsilon subdivisions,2WKIH@28221|Deltaproteobacteria,2MI42@213118|Desulfobacterales	28221|Deltaproteobacteria	Q	PFAM amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
k141_3584_2	1005048.CFU_2039	2.37e-55	182.0	COG1652@1|root,COG1652@2|Bacteria,1PX8K@1224|Proteobacteria,2WCR2@28216|Betaproteobacteria,47834@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_3584_3	373994.Riv7116_1697	3.36e-51	181.0	COG3500@1|root,COG3500@2|Bacteria,1G4DS@1117|Cyanobacteria,1HMCU@1161|Nostocales	1117|Cyanobacteria	S	PFAM Phage late control gene D protein (GPD)	-	-	-	-	-	-	-	-	-	-	-	-	Phage_GPD
k141_3584_4	1291050.JAGE01000001_gene2795	7.62e-46	158.0	COG3501@1|root,COG3501@2|Bacteria,1V234@1239|Firmicutes,24MBD@186801|Clostridia	186801|Clostridia	S	Rhs element vgr protein	-	-	-	-	-	-	-	-	-	-	-	-	Phage_base_V
k141_3584_5	1499967.BAYZ01000101_gene3607	4.12e-60	188.0	COG4104@1|root,COG4104@2|Bacteria	2|Bacteria	T	PAAR repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	PAAR_motif
k141_3584_6	1300345.LF41_3023	6.21e-25	99.4	COG3628@1|root,COG3628@2|Bacteria,1N23A@1224|Proteobacteria,1SCDV@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	GPW gp25 family protein	-	-	-	ko:K06903	-	-	-	-	ko00000	-	-	-	GPW_gp25
k141_3584_7	684949.ATTJ01000001_gene1785	4.68e-11	75.5	COG3299@1|root,COG3299@2|Bacteria	2|Bacteria	S	Baseplate J-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Baseplate_J
k141_1523_1	1121405.dsmv_2988	5.89e-123	367.0	COG1509@1|root,COG1509@2|Bacteria,1MUPJ@1224|Proteobacteria,42NCM@68525|delta/epsilon subdivisions,2WKN6@28221|Deltaproteobacteria,2MIXH@213118|Desulfobacterales	28221|Deltaproteobacteria	E	lysine 2,3-aminomutase	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_14
k141_3927_1	1304885.AUEY01000001_gene3268	8.71e-167	476.0	28MQN@1|root,2ZAZG@2|Bacteria,1MVVQ@1224|Proteobacteria,42MMM@68525|delta/epsilon subdivisions,2WKA1@28221|Deltaproteobacteria,2MHKP@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_3927_2	1232437.KL661955_gene2362	1.02e-63	199.0	COG1246@1|root,COG1246@2|Bacteria,1RHT7@1224|Proteobacteria,42SGE@68525|delta/epsilon subdivisions,2WP91@28221|Deltaproteobacteria,2MK41@213118|Desulfobacterales	28221|Deltaproteobacteria	E	PFAM GCN5-related N-acetyltransferase	argA	-	2.3.1.1	ko:K00619	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_0946	Acetyltransf_1,Acetyltransf_7
k141_3927_3	933262.AXAM01000027_gene2094	8.64e-53	187.0	COG0744@1|root,COG0744@2|Bacteria,1QTST@1224|Proteobacteria,43BJ8@68525|delta/epsilon subdivisions,2X708@28221|Deltaproteobacteria,2MJ7A@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Transglycosylase	-	-	2.4.1.129,3.4.16.4	ko:K05366,ko:K21464	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
k141_3585_1	933262.AXAM01000127_gene1028	4.77e-116	343.0	COG0138@1|root,COG0138@2|Bacteria,1MUDQ@1224|Proteobacteria,42MV4@68525|delta/epsilon subdivisions,2WKHZ@28221|Deltaproteobacteria,2MI2I@213118|Desulfobacterales	28221|Deltaproteobacteria	F	PFAM AICARFT IMPCHase bienzyme	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
k141_818_1	880073.Calab_3293	6.83e-36	140.0	COG3829@1|root,COG3829@2|Bacteria,2NQNU@2323|unclassified Bacteria	2|Bacteria	KT	Sigma-54 interaction domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HTH_8,Sigma54_activat
k141_818_3	706587.Desti_1101	8.44e-39	145.0	COG0845@1|root,COG0845@2|Bacteria,1R4JA@1224|Proteobacteria,42SQN@68525|delta/epsilon subdivisions,2WP8X@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K21137	-	M00821	-	-	ko00000,ko00002,ko02000	2.A.6.2.27,8.A.1	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
k141_4253_1	595494.Tola_1946	2.29e-56	189.0	COG2211@1|root,COG2211@2|Bacteria,1MVUM@1224|Proteobacteria,1RP5J@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	COG2211 Na melibiose symporter and related transporters	-	-	-	ko:K03292,ko:K16139	-	-	-	-	ko00000,ko02000	2.A.2	-	-	MFS_2
k141_4253_2	595494.Tola_1947	1.24e-301	838.0	COG3533@1|root,COG3533@2|Bacteria,1MWEN@1224|Proteobacteria,1RSMM@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	protein conserved in bacteria	-	-	-	ko:K09955	-	-	-	-	ko00000	-	-	-	Glyco_hydro_127
k141_5211_1	1517681.HW45_00330	2.38e-67	207.0	COG0511@1|root,COG0511@2|Bacteria,1RCXA@1224|Proteobacteria,1S3YP@1236|Gammaproteobacteria,1XWV0@135623|Vibrionales	135623|Vibrionales	I	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA	accB	-	-	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742	RC00040,RC00367	ko00000,ko00001,ko00002	-	-	-	Biotin_lipoyl
k141_1658_2	55601.VANGNB10_cII0994	9.06e-149	431.0	COG1196@1|root,COG1196@2|Bacteria,1QUH3@1224|Proteobacteria,1T1YQ@1236|Gammaproteobacteria,1Y330@135623|Vibrionales	135623|Vibrionales	D	PEGA domain	-	-	-	-	-	-	-	-	-	-	-	-	PEGA
k141_1659_1	1515746.HR45_19315	7.63e-50	172.0	COG1477@1|root,COG1477@2|Bacteria,1MW6K@1224|Proteobacteria,1RNMZ@1236|Gammaproteobacteria,2QAHN@267890|Shewanellaceae	1236|Gammaproteobacteria	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	apbE	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
k141_1659_2	439235.Dalk_1716	1.78e-134	387.0	COG1024@1|root,COG1024@2|Bacteria,1PJ4R@1224|Proteobacteria,42P1A@68525|delta/epsilon subdivisions,2WM73@28221|Deltaproteobacteria,2MIVM@213118|Desulfobacterales	28221|Deltaproteobacteria	I	enoyl-CoA hydratase isomerase family	-	-	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
k141_2975_1	1219065.VPR01S_12_00870	6.72e-136	392.0	COG2035@1|root,COG2035@2|Bacteria,1MXVI@1224|Proteobacteria,1RN4B@1236|Gammaproteobacteria,1XSHN@135623|Vibrionales	135623|Vibrionales	S	Domain of unknown function (DUF368)	-	-	-	ko:K08974	-	-	-	-	ko00000	-	-	-	DUF368
k141_2975_2	243277.VC_A0042	2.03e-110	325.0	2CA3C@1|root,33HT2@2|Bacteria,1R8P5@1224|Proteobacteria,1RRNR@1236|Gammaproteobacteria,1XUS9@135623|Vibrionales	135623|Vibrionales	S	Flagellar protein YcgR	-	-	-	-	-	-	-	-	-	-	-	-	PilZ,YcgR_2
k141_2975_3	1191299.AJYX01000097_gene1863	1.75e-226	641.0	COG0457@1|root,COG2199@1|root,COG0457@2|Bacteria,COG3706@2|Bacteria,1NC00@1224|Proteobacteria,1SNFZ@1236|Gammaproteobacteria,1XSA5@135623|Vibrionales	135623|Vibrionales	T	COG2199 FOG GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
k141_2975_4	29495.EA26_13165	8.13e-75	241.0	COG0457@1|root,COG0457@2|Bacteria,1NFT4@1224|Proteobacteria,1SPMW@1236|Gammaproteobacteria,1XSHX@135623|Vibrionales	135623|Vibrionales	S	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_2661_1	318464.IO99_07650	1.68e-64	214.0	COG0477@1|root,COG2814@2|Bacteria,1UZPE@1239|Firmicutes,2490R@186801|Clostridia,36WDV@31979|Clostridiaceae	186801|Clostridia	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_3
k141_2661_3	1292035.H476_3153	5.41e-127	376.0	COG2038@1|root,COG2038@2|Bacteria,1TPC1@1239|Firmicutes,25DH5@186801|Clostridia	186801|Clostridia	H	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB)	cobT	-	2.4.2.21	ko:K00768	ko00860,ko01100,map00860,map01100	M00122	R04148	RC00033,RC00063	ko00000,ko00001,ko00002,ko01000	-	-	-	DBI_PRT
k141_2661_4	1347392.CCEZ01000007_gene2010	3.41e-105	315.0	COG0122@1|root,COG0122@2|Bacteria,1TQAF@1239|Firmicutes,2495X@186801|Clostridia,36DTH@31979|Clostridiaceae	186801|Clostridia	L	8-oxoguanine DNA glycosylase	alkA	-	4.2.99.18	ko:K03660	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD,OGG_N
k141_2661_5	1286171.EAL2_c17530	8.79e-223	629.0	COG1502@1|root,COG1502@2|Bacteria,1TPKY@1239|Firmicutes,247UR@186801|Clostridia,25UTH@186806|Eubacteriaceae	186801|Clostridia	I	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol	cls	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2,PLDc_N
k141_2661_6	1297617.JPJD01000072_gene1815	2.33e-29	112.0	COG1595@1|root,COG1595@2|Bacteria,1V734@1239|Firmicutes,24MQB@186801|Clostridia,268VU@186813|unclassified Clostridiales	186801|Clostridia	K	Sigma-70, region 4	sigV	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
k141_2661_7	457421.CBFG_00856	2.03e-41	151.0	2DBFK@1|root,2Z8Z7@2|Bacteria,1TQKG@1239|Firmicutes,2482J@186801|Clostridia,2688R@186813|unclassified Clostridiales	186801|Clostridia	S	Protein of unknown function (DUF3298)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3298,DUF4163
k141_2661_8	926692.AZYG01000094_gene1965	3.99e-29	122.0	COG0726@1|root,COG0726@2|Bacteria,1V4PK@1239|Firmicutes,25BCW@186801|Clostridia,3WBMS@53433|Halanaerobiales	186801|Clostridia	M	PFAM Polysaccharide deacetylase	-	-	3.5.1.104	ko:K22278	-	-	-	-	ko00000,ko01000	-	-	-	LysM,Polysacc_deac_1
k141_2661_9	1347392.CCEZ01000049_gene1331	4.05e-125	378.0	COG0534@1|root,COG0534@2|Bacteria,1TQ56@1239|Firmicutes,248YU@186801|Clostridia,36DVM@31979|Clostridiaceae	186801|Clostridia	V	MATE efflux family protein	-	-	-	-	-	-	-	-	-	-	-	-	MatE
k141_2661_11	536232.CLM_1431	6.69e-08	54.3	COG5416@1|root,COG5416@2|Bacteria,1VK4W@1239|Firmicutes,24RJX@186801|Clostridia,36NC1@31979|Clostridiaceae	186801|Clostridia	S	Lipopolysaccharide assembly protein A domain	-	-	-	-	-	-	-	-	-	-	-	-	LapA_dom
k141_2661_12	536232.CLM_1884	4.99e-213	596.0	COG1454@1|root,COG1454@2|Bacteria,1TPB4@1239|Firmicutes,247IQ@186801|Clostridia,36DKD@31979|Clostridiaceae	186801|Clostridia	C	alcohol dehydrogenase	adh	-	-	-	-	-	-	-	-	-	-	-	Fe-ADH
k141_2661_13	999411.HMPREF1092_02299	3.05e-154	439.0	COG0543@1|root,COG0543@2|Bacteria,1TP6D@1239|Firmicutes,247YB@186801|Clostridia,36DFV@31979|Clostridiaceae	186801|Clostridia	C	Oxidoreductase	pyrK_1	-	1.18.1.2,1.19.1.1	ko:K00528,ko:K16951	ko00920,ko01120,map00920,map01120	-	R00858,R10146,R10159	RC00065	ko00000,ko00001,ko01000	-	-	-	DHODB_Fe-S_bind,NAD_binding_1
k141_2661_14	1226325.HMPREF1548_05535	9.34e-238	665.0	COG0493@1|root,COG0493@2|Bacteria,1TQ1A@1239|Firmicutes,248EK@186801|Clostridia,36E1P@31979|Clostridiaceae	186801|Clostridia	C	glutamate synthase (NADPH), homotetrameric	gltA	-	1.17.1.9,1.4.1.13,1.4.1.14	ko:K00123,ko:K00266	ko00250,ko00630,ko00680,ko00910,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00250,map00630,map00680,map00910,map01100,map01110,map01120,map01130,map01200,map01230	-	R00093,R00114,R00248,R00519	RC00006,RC00010,RC02796,RC02799	ko00000,ko00001,ko01000	-	-	-	DHODB_Fe-S_bind,Fer4_20,Pyr_redox_2
k141_2661_15	1121324.CLIT_20c00280	2.61e-46	150.0	COG0234@1|root,COG0234@2|Bacteria,1V9ZM@1239|Firmicutes,24MMM@186801|Clostridia,25RM6@186804|Peptostreptococcaceae	186801|Clostridia	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	-	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
k141_2661_16	1121324.CLIT_20c00290	4.35e-288	799.0	COG0459@1|root,COG0459@2|Bacteria,1TP1T@1239|Firmicutes,248BG@186801|Clostridia	186801|Clostridia	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
k141_2976_1	338969.Rfer_1986	1.16e-17	85.9	COG1639@1|root,COG1639@2|Bacteria,1NQD3@1224|Proteobacteria,2VPTF@28216|Betaproteobacteria,4ABWF@80864|Comamonadaceae	28216|Betaproteobacteria	T	HDOD domain	-	-	-	-	-	-	-	-	-	-	-	-	HDOD
k141_2977_1	1173020.Cha6605_2100	3.28e-66	215.0	COG3344@1|root,COG3344@2|Bacteria,1G791@1117|Cyanobacteria	1117|Cyanobacteria	L	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	GIIM,RVT_1
k141_2662_1	1304885.AUEY01000010_gene1646	9.1e-131	385.0	COG0305@1|root,COG0305@2|Bacteria,1MUG9@1224|Proteobacteria,42M7X@68525|delta/epsilon subdivisions,2WJCA@28221|Deltaproteobacteria,2MHKJ@213118|Desulfobacterales	28221|Deltaproteobacteria	L	it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins	dnaB	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
k141_2662_2	1121405.dsmv_0370	1.36e-56	196.0	COG2262@1|root,COG2262@2|Bacteria,1MUA0@1224|Proteobacteria,42NA6@68525|delta/epsilon subdivisions,2WIMU@28221|Deltaproteobacteria,2MJ6H@213118|Desulfobacterales	28221|Deltaproteobacteria	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
k141_1660_2	402880.MmarC5_0497	4.67e-85	285.0	COG0367@1|root,arCOG00071@2157|Archaea,2XV5E@28890|Euryarchaeota,23RCU@183939|Methanococci	183939|Methanococci	E	TIGRFAM asparagine synthase (glutamine-hydrolyzing)	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
k141_3296_2	1111732.AZOD01000025_gene1733	1.74e-48	163.0	COG2227@1|root,COG2227@2|Bacteria,1QUAF@1224|Proteobacteria,1S2ZT@1236|Gammaproteobacteria	1236|Gammaproteobacteria	H	COG0500 SAM-dependent methyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23,Methyltransf_25
k141_3296_3	1307834.BARL01000001_gene233	1.64e-128	384.0	COG1061@1|root,COG3410@1|root,COG1061@2|Bacteria,COG3410@2|Bacteria,1R703@1224|Proteobacteria	1224|Proteobacteria	L	Uncharacterized conserved protein (DUF2075)	-	-	-	ko:K09384	-	-	-	-	ko00000	-	-	-	DUF2075
k141_3296_4	211586.SO_4394	3.65e-22	91.3	COG0607@1|root,COG0607@2|Bacteria,1QR7S@1224|Proteobacteria,1RU3G@1236|Gammaproteobacteria,2QC8H@267890|Shewanellaceae	1236|Gammaproteobacteria	P	PFAM Rhodanese domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
k141_3296_5	1348635.BBJY01000001_gene2690	1.47e-128	371.0	COG0121@1|root,COG0121@2|Bacteria,1PX9X@1224|Proteobacteria,1SBGN@1236|Gammaproteobacteria,1XUET@135623|Vibrionales	135623|Vibrionales	S	Glutamine amidotransferases class-II	-	-	-	-	-	-	-	-	-	-	-	-	GATase_4
k141_3296_6	1238450.VIBNISOn1_790036	1.31e-272	757.0	COG1115@1|root,COG1115@2|Bacteria,1MUI3@1224|Proteobacteria,1RMNF@1236|Gammaproteobacteria,1XU2Z@135623|Vibrionales	135623|Vibrionales	U	COG1115 Na alanine symporter	-	-	-	ko:K03310	-	-	-	-	ko00000	2.A.25	-	-	Na_Ala_symp
k141_3296_10	672.VV93_v1c24610	3.33e-68	207.0	COG0347@1|root,COG0347@2|Bacteria,1RGWK@1224|Proteobacteria,1S67I@1236|Gammaproteobacteria,1XXDH@135623|Vibrionales	135623|Vibrionales	K	Belongs to the P(II) protein family	glnK	-	-	ko:K04752	-	-	-	-	ko00000	-	-	-	P-II
k141_3296_12	29495.EA26_10410	1.76e-128	374.0	COG0702@1|root,COG0702@2|Bacteria,1QRSF@1224|Proteobacteria,1S5R4@1236|Gammaproteobacteria,1XVWA@135623|Vibrionales	135623|Vibrionales	GM	NmrA-like family	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10,NmrA
k141_3296_13	104623.Ser39006_03589	3.5e-68	209.0	COG1846@1|root,COG1846@2|Bacteria,1RM70@1224|Proteobacteria,1S83P@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	MarR family	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
k141_3296_14	104623.Ser39006_03590	0.0	1147.0	COG0178@1|root,COG0178@2|Bacteria,1MW0W@1224|Proteobacteria,1RMS9@1236|Gammaproteobacteria,401NJ@613|Serratia	1236|Gammaproteobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
k141_3296_15	1348635.BBJY01000018_gene2327	0.0	1596.0	COG0060@1|root,COG0060@2|Bacteria,1MVBQ@1224|Proteobacteria,1RMTF@1236|Gammaproteobacteria,1Y08T@135623|Vibrionales	135623|Vibrionales	J	Anticodon-binding domain of tRNA	-	-	-	-	-	-	-	-	-	-	-	-	Anticodon_1,tRNA-synt_1
k141_3296_16	1283284.AZUK01000001_gene1403	9.14e-121	357.0	COG0583@1|root,COG0583@2|Bacteria,1MW16@1224|Proteobacteria,1RS6U@1236|Gammaproteobacteria,1Y4CU@135624|Aeromonadales	135624|Aeromonadales	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
k141_3296_17	1500894.JQNN01000001_gene4540	3.25e-119	358.0	COG0477@1|root,COG2814@2|Bacteria,1MVVW@1224|Proteobacteria,2VIUY@28216|Betaproteobacteria,473ZN@75682|Oxalobacteraceae	28216|Betaproteobacteria	EGP	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
k141_3296_18	672.VV93_v1c44110	3.24e-189	527.0	COG0191@1|root,COG0191@2|Bacteria,1MURX@1224|Proteobacteria,1RQUC@1236|Gammaproteobacteria,1XT4A@135623|Vibrionales	135623|Vibrionales	G	in enteric bacteria there are two D-tagatose 1,6-bisphosphate-specific aldolases KbaY (also called AgaY), involved in catabolism of N-acetyl-galactosamine and D-galactosamine, and GatY which is part of the galactitol catabolism pathway	gatY	-	4.1.2.13,4.1.2.40	ko:K01624,ko:K08302	ko00010,ko00030,ko00051,ko00052,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00052,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167,M00344,M00345	R01068,R01069,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	F_bP_aldolase
k141_3296_19	314292.VAS14_15599	9.51e-223	621.0	COG1820@1|root,COG1820@2|Bacteria,1MW8Y@1224|Proteobacteria,1RMRV@1236|Gammaproteobacteria,1XV7M@135623|Vibrionales	135623|Vibrionales	G	Belongs to the metallo-dependent hydrolases superfamily. NagA family	-	-	3.5.1.25	ko:K02079	ko00052,map00052	-	R05168	RC00166,RC00300	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
k141_3296_20	314292.VAS14_15594	8.67e-76	229.0	COG2893@1|root,COG2893@2|Bacteria,1Q8RH@1224|Proteobacteria,1S2UG@1236|Gammaproteobacteria,1XWXR@135623|Vibrionales	135623|Vibrionales	G	COG2893 Phosphotransferase system, mannose fructose-specific component IIA	-	-	-	ko:K02744	ko00052,ko02060,map00052,map02060	M00277,M00287	R08366,R08367	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.6.1.4,4.A.6.1.5	-	-	EIIA-man
k141_3296_21	1238450.VIBNISOn1_270049	1.54e-176	496.0	COG3716@1|root,COG3716@2|Bacteria,1N45J@1224|Proteobacteria,1RSNE@1236|Gammaproteobacteria,1XW8W@135623|Vibrionales	135623|Vibrionales	G	COG3716 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IID	-	-	-	ko:K02747	ko00052,ko02060,map00052,map02060	M00277	R08366	RC00017	ko00000,ko00001,ko00002,ko02000	4.A.6.1.4	-	-	EIID-AGA
k141_3296_22	314292.VAS14_15584	1.14e-160	452.0	COG3715@1|root,COG3715@2|Bacteria,1NBYA@1224|Proteobacteria,1RQ1Z@1236|Gammaproteobacteria,1XUPU@135623|Vibrionales	135623|Vibrionales	G	COG3715 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IIC	-	-	-	ko:K02746	ko00052,ko02060,map00052,map02060	M00277	R08366	RC00017	ko00000,ko00001,ko00002,ko02000	4.A.6.1.4	-	-	EII-Sor
k141_3296_23	672.VV93_v1c44180	1.97e-100	292.0	COG3444@1|root,COG3444@2|Bacteria,1R4ES@1224|Proteobacteria,1RQ2P@1236|Gammaproteobacteria,1XW4C@135623|Vibrionales	135623|Vibrionales	G	COG3444 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IIB	-	-	-	ko:K02745	ko00052,ko02060,map00052,map02060	M00277	R08366	RC00017	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.6.1.4	-	-	PTSIIB_sorb
k141_3296_24	314292.VAS14_15574	6.64e-233	646.0	COG2222@1|root,COG2222@2|Bacteria,1NICK@1224|Proteobacteria,1RRU0@1236|Gammaproteobacteria,1XUPQ@135623|Vibrionales	135623|Vibrionales	G	SIS domain	agaS	-	-	ko:K02082	-	-	-	-	ko00000,ko01000	-	-	-	SIS
k141_3296_25	870967.VIS19158_19772	5.17e-276	759.0	COG4573@1|root,COG4573@2|Bacteria,1MW3Q@1224|Proteobacteria,1RQAU@1236|Gammaproteobacteria,1XVU3@135623|Vibrionales	135623|Vibrionales	G	Tagatose 6 phosphate kinase	-	-	-	ko:K16371	ko00052,ko01100,map00052,map01100	-	R01069	RC00438,RC00439	ko00000,ko00001	-	-	-	Tagatose_6_P_K
k141_3296_26	870967.VIS19158_19777	5.92e-163	458.0	COG1349@1|root,COG1349@2|Bacteria,1MUJT@1224|Proteobacteria,1SZXU@1236|Gammaproteobacteria,1XVFB@135623|Vibrionales	135623|Vibrionales	K	COG1349 Transcriptional regulators of sugar metabolism	-	-	-	ko:K02081	-	-	-	-	ko00000,ko03000	-	-	-	DeoRC,HTH_DeoR
k141_3296_27	314292.VAS14_15559	1.6e-157	444.0	COG1349@1|root,COG1349@2|Bacteria,1MUJT@1224|Proteobacteria,1SZXU@1236|Gammaproteobacteria,1XVFB@135623|Vibrionales	135623|Vibrionales	K	COG1349 Transcriptional regulators of sugar metabolism	-	-	-	ko:K02081	-	-	-	-	ko00000,ko03000	-	-	-	DeoRC,HTH_DeoR
k141_3296_28	400668.Mmwyl1_2743	1.25e-122	370.0	COG0840@1|root,COG3829@1|root,COG0840@2|Bacteria,COG3829@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	NT	chemotaxis, protein	-	-	-	ko:K03406,ko:K05875	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CHASE3,HAMP,MCPsignal,TarH,dCache_1
k141_3296_30	400668.Mmwyl1_2975	6.76e-254	705.0	COG0534@1|root,COG0534@2|Bacteria,1R4H5@1224|Proteobacteria,1RS0B@1236|Gammaproteobacteria,1XP1J@135619|Oceanospirillales	135619|Oceanospirillales	V	MatE	-	-	-	-	-	-	-	-	-	-	-	-	MatE
k141_3296_31	400668.Mmwyl1_2976	2.83e-188	526.0	COG0583@1|root,COG0583@2|Bacteria,1R6B4@1224|Proteobacteria,1SWJC@1236|Gammaproteobacteria,1XPHS@135619|Oceanospirillales	135619|Oceanospirillales	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
k141_3296_32	710111.FraQA3DRAFT_2683	4.49e-17	87.4	COG1396@1|root,COG1396@2|Bacteria,2GJS3@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional	-	-	-	-	-	-	-	-	-	-	-	-	HTH_31
k141_3296_33	1224318.DT73_04065	2.29e-170	489.0	COG0477@1|root,COG2814@2|Bacteria,1MW19@1224|Proteobacteria,1RMSZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	EGP	Major facilitator superfamily	-	-	-	ko:K07552	-	-	-	-	ko00000,ko02000	2.A.1.2	-	-	MFS_1
k141_3296_34	1141662.OOA_04612	7.94e-171	489.0	COG0477@1|root,COG2814@2|Bacteria,1MU9G@1224|Proteobacteria,1RPHV@1236|Gammaproteobacteria,3Z7GB@586|Providencia	1236|Gammaproteobacteria	P	Involved in the efflux of sugars. The physiological role may be the reduction of the intracellular concentration of toxic sugars or sugar metabolites	-	-	-	ko:K03445	-	-	-	-	ko00000,ko02000	2.A.1.2.26	-	-	MFS_1
k141_3296_35	1141662.OOA_04607	1.86e-182	513.0	COG0667@1|root,COG0667@2|Bacteria,1MVEH@1224|Proteobacteria,1RPX5@1236|Gammaproteobacteria,3Z9QZ@586|Providencia	1236|Gammaproteobacteria	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
k141_3296_36	1141662.OOA_04602	4.47e-155	443.0	COG0583@1|root,COG0583@2|Bacteria,1MWVB@1224|Proteobacteria,1RZTS@1236|Gammaproteobacteria,3Z9US@586|Providencia	1236|Gammaproteobacteria	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
k141_3296_37	945543.VIBR0546_18566	0.0	951.0	COG0518@1|root,COG0519@1|root,COG0518@2|Bacteria,COG0519@2|Bacteria,1MU2A@1224|Proteobacteria,1RP81@1236|Gammaproteobacteria,1XTWC@135623|Vibrionales	135623|Vibrionales	F	Catalyzes the synthesis of GMP from XMP	guaA	GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase
k141_3296_38	243277.VC_0767	8.91e-299	821.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,1MUJM@1224|Proteobacteria,1RMT8@1236|Gammaproteobacteria,1XT7Z@135623|Vibrionales	135623|Vibrionales	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	guaB	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH
k141_3296_39	674977.VMC_07400	3.83e-201	572.0	COG1570@1|root,COG1570@2|Bacteria,1MUA4@1224|Proteobacteria,1RNAZ@1236|Gammaproteobacteria,1XSYD@135623|Vibrionales	135623|Vibrionales	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseA	GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008855,GO:0009056,GO:0009057,GO:0009318,GO:0009987,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0019439,GO:0032991,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575,GO:1902494	3.1.11.6	ko:K03601	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
k141_3296_40	1517681.HW45_15950	2.95e-30	108.0	COG1198@1|root,COG1198@2|Bacteria,1NHFG@1224|Proteobacteria,1SGTI@1236|Gammaproteobacteria,1XYUA@135623|Vibrionales	135623|Vibrionales	L	zinc-ribbons	-	-	-	-	-	-	-	-	-	-	-	-	zinc-ribbons_6
k141_3296_41	1123284.KB899047_gene1649	1.38e-123	363.0	COG0697@1|root,COG0697@2|Bacteria,1UHT1@1239|Firmicutes,4HCWY@91061|Bacilli	91061|Bacilli	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
k141_3296_42	1219065.VPR01S_18_00360	9.27e-311	852.0	COG1160@1|root,COG1160@2|Bacteria,1MU9S@1224|Proteobacteria,1RMSF@1236|Gammaproteobacteria,1XTH0@135623|Vibrionales	135623|Vibrionales	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0005488,GO:0005525,GO:0017076,GO:0019001,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
k141_3296_43	945550.VISI1226_15266	2.73e-151	439.0	COG1520@1|root,COG1520@2|Bacteria,1MXIJ@1224|Proteobacteria,1RN4V@1236|Gammaproteobacteria,1XSD2@135623|Vibrionales	135623|Vibrionales	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamB	GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0055114	-	ko:K17713	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	PQQ_2,PQQ_3
k141_3296_44	945543.VIBR0546_18526	1.57e-78	240.0	COG2976@1|root,COG2976@2|Bacteria,1N117@1224|Proteobacteria,1SASA@1236|Gammaproteobacteria,1XTXY@135623|Vibrionales	135623|Vibrionales	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	TPR_21
k141_3296_45	1348635.BBJY01000023_gene2022	2.62e-265	731.0	COG0124@1|root,COG0124@2|Bacteria,1MV2K@1224|Proteobacteria,1RPHI@1236|Gammaproteobacteria,1XTDT@135623|Vibrionales	135623|Vibrionales	J	Histidyl-tRNA synthetase	hisS	GO:0003674,GO:0003824,GO:0004812,GO:0004821,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006427,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
k141_3296_46	675815.VOA_000838	3.74e-233	645.0	COG0821@1|root,COG0821@2|Bacteria,1MUAX@1224|Proteobacteria,1RMXZ@1236|Gammaproteobacteria,1XSUH@135623|Vibrionales	135623|Vibrionales	I	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate	ispG	GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576	1.17.7.1,1.17.7.3	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R08689,R10859	RC01486	ko00000,ko00001,ko00002,ko01000	-	-	-	GcpE
k141_3296_47	870967.VIS19158_05623	2.31e-62	208.0	COG1426@1|root,COG1426@2|Bacteria,1N240@1224|Proteobacteria,1RQMV@1236|Gammaproteobacteria,1XSGH@135623|Vibrionales	135623|Vibrionales	S	protein conserved in bacteria	rodZ	-	-	ko:K15539	-	-	-	-	ko00000	-	-	-	DUF4115,HTH_25
k141_3296_48	243277.VC_0757	1.18e-236	654.0	COG0820@1|root,COG0820@2|Bacteria,1MUYK@1224|Proteobacteria,1RMUI@1236|Gammaproteobacteria,1XSQG@135623|Vibrionales	135623|Vibrionales	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Radical_SAM
k141_3296_50	345073.VC395_0772	2.97e-241	671.0	COG0260@1|root,COG0260@2|Bacteria,1MUIN@1224|Proteobacteria,1RNFI@1236|Gammaproteobacteria,1XUTG@135623|Vibrionales	135623|Vibrionales	E	Probably plays an important role in intracellular peptide degradation	pepB	GO:0003674,GO:0003824,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:0140096,GO:1901564	3.4.11.23	ko:K07751	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	DUF3663,Peptidase_M17
k141_3296_53	1348635.BBJY01000023_gene2014	0.0	939.0	COG0443@1|root,COG0443@2|Bacteria,1MVQI@1224|Proteobacteria,1RN74@1236|Gammaproteobacteria,1XT9W@135623|Vibrionales	135623|Vibrionales	O	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB	hscA	GO:0006457,GO:0008150,GO:0009987	-	ko:K04044	-	-	-	-	ko00000,ko03110	1.A.33	-	-	HSP70
k141_3296_54	223926.28805585	1.83e-56	182.0	COG1076@1|root,COG1076@2|Bacteria,1RHZX@1224|Proteobacteria,1S9YH@1236|Gammaproteobacteria,1XTU9@135623|Vibrionales	135623|Vibrionales	O	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA	hscB	GO:0006457,GO:0008150,GO:0009987	-	ko:K04082	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,HSCB_C
k141_3296_57	1219076.N646_2754	2.95e-266	732.0	COG1104@1|root,COG1104@2|Bacteria,1MU1C@1224|Proteobacteria,1RNCD@1236|Gammaproteobacteria,1XSAE@135623|Vibrionales	135623|Vibrionales	H	Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins	iscS	GO:0003674,GO:0003824,GO:0008483,GO:0016740,GO:0016769	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
k141_3296_58	617140.AJZE01000057_gene1982	8.25e-87	259.0	COG1959@1|root,COG1959@2|Bacteria,1RDA4@1224|Proteobacteria,1S3RW@1236|Gammaproteobacteria,1XTCH@135623|Vibrionales	135623|Vibrionales	K	Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins	iscR	-	-	ko:K13643	-	-	-	-	ko00000,ko03000	-	-	-	Rrf2
k141_3296_59	1348635.BBJY01000023_gene2008	4.31e-112	328.0	COG0565@1|root,COG0565@2|Bacteria,1N47Y@1224|Proteobacteria,1RPD3@1236|Gammaproteobacteria,1XSWM@135623|Vibrionales	135623|Vibrionales	J	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA	trmJ	-	2.1.1.200	ko:K15396	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
k141_3296_60	223926.28805579	7.1e-164	461.0	COG0483@1|root,COG0483@2|Bacteria,1MUQT@1224|Proteobacteria,1RNME@1236|Gammaproteobacteria,1XSBJ@135623|Vibrionales	135623|Vibrionales	G	COG0483 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family	suhB	GO:0003674,GO:0003824,GO:0005975,GO:0006020,GO:0006066,GO:0006793,GO:0006796,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008934,GO:0009056,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019637,GO:0019751,GO:0023052,GO:0042578,GO:0043647,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0046164,GO:0046174,GO:0046434,GO:0046838,GO:0046855,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0052745,GO:0052834,GO:0065007,GO:0071545,GO:0071704,GO:1901575,GO:1901615,GO:1901616	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
k141_3296_61	945550.VISI1226_15491	4.84e-172	486.0	COG0341@1|root,COG0341@2|Bacteria,1MU74@1224|Proteobacteria,1RNTY@1236|Gammaproteobacteria,1XTB0@135623|Vibrionales	135623|Vibrionales	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secF	-	-	ko:K03074	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
k141_3296_64	1238450.VIBNISOn1_1550004	6.45e-263	721.0	COG0343@1|root,COG0343@2|Bacteria,1MUCA@1224|Proteobacteria,1RMY3@1236|Gammaproteobacteria,1XTCG@135623|Vibrionales	135623|Vibrionales	F	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	tgt	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008479,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
k141_3025_1	298386.PBPRB0076	7.63e-231	645.0	COG2704@1|root,COG2704@2|Bacteria,1MVGA@1224|Proteobacteria,1RSB4@1236|Gammaproteobacteria,1XZSI@135623|Vibrionales	1236|Gammaproteobacteria	P	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane	-	-	-	ko:K07791	-	-	-	-	ko00000,ko02000	2.A.13.1	-	-	DcuA_DcuB
k141_3025_2	675812.VHA_000233	1.61e-265	736.0	COG1027@1|root,COG1027@2|Bacteria,1R9JY@1224|Proteobacteria,1RP5Z@1236|Gammaproteobacteria,1XSMK@135623|Vibrionales	135623|Vibrionales	E	Aspartate ammonia-lyase	aspA	-	4.3.1.1	ko:K01744	ko00250,ko01100,map00250,map01100	-	R00490	RC00316,RC02799	ko00000,ko00001,ko01000	-	-	-	FumaraseC_C,Lyase_1
k141_3324_1	675814.VIC_005078	3.48e-249	798.0	COG3210@1|root,COG3210@2|Bacteria,1MX2K@1224|Proteobacteria,1RNRK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	U	Large exoproteins involved in heme utilization or adhesion	-	-	-	ko:K15125	ko05133,map05133	-	-	-	ko00000,ko00001,ko00536	-	-	-	DUF637,Fil_haemagg_2,Haemagg_act
k141_1690_2	1408424.JHYI01000012_gene2287	4.75e-17	79.3	COG2089@1|root,COG2089@2|Bacteria,1TS09@1239|Firmicutes,4HA1Y@91061|Bacilli,1ZBZ4@1386|Bacillus	91061|Bacilli	M	acid synthase	neuB	-	2.5.1.101,2.5.1.56	ko:K01654,ko:K18430	ko00520,ko01100,map00520,map01100	-	R01804,R04435,R10304	RC00159	ko00000,ko00001,ko01000	-	-	-	NeuB,SAF
k141_1691_1	1280001.BAOA01000038_gene4402	1.76e-151	432.0	COG1360@1|root,COG1360@2|Bacteria,1QUFR@1224|Proteobacteria,1T1XE@1236|Gammaproteobacteria,1XSEG@135623|Vibrionales	135623|Vibrionales	N	Flagellar motor protein	motB	-	-	ko:K02557	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	MotB_plug,OmpA
k141_1691_3	55601.VANGNB10_cI0767c	1.1e-37	127.0	COG1722@1|root,COG1722@2|Bacteria,1N72V@1224|Proteobacteria,1SC7N@1236|Gammaproteobacteria,1XYBF@135623|Vibrionales	135623|Vibrionales	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseB	GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008855,GO:0009056,GO:0009057,GO:0009318,GO:0009987,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0019439,GO:0032991,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575,GO:1902494	3.1.11.6	ko:K03602	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_S
k141_1692_1	1347392.CCEZ01000010_gene2412	1.28e-129	388.0	COG1757@1|root,COG1757@2|Bacteria,1TQPI@1239|Firmicutes,2495U@186801|Clostridia,36E2J@31979|Clostridiaceae	186801|Clostridia	C	hmm pf03553	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_antiporter
k141_1692_2	350688.Clos_2825	2.17e-147	435.0	COG2204@1|root,COG2204@2|Bacteria,1VSKG@1239|Firmicutes,24ZP4@186801|Clostridia,36EVK@31979|Clostridiaceae	186801|Clostridia	T	Two component, sigma54 specific, transcriptional regulator, Fis family	-	-	-	ko:K02481	-	-	-	-	ko00000,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
k141_3028_1	1117314.PCIT_20134	1.15e-26	105.0	COG1518@1|root,COG1518@2|Bacteria,1MUXH@1224|Proteobacteria,1RP48@1236|Gammaproteobacteria,2Q3NP@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	L	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette	cas1	-	-	ko:K15342	-	-	-	-	ko00000,ko02048,ko03400	-	-	-	Cas_Cas1
k141_3028_2	29495.EA26_00060	0.0	1413.0	COG1203@1|root,COG1203@2|Bacteria,1MVZF@1224|Proteobacteria,1RQH5@1236|Gammaproteobacteria,1XWDM@135623|Vibrionales	135623|Vibrionales	L	CRISPR-associated helicase, Cas3	-	-	-	ko:K07012	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	-
k141_3028_3	1127673.GLIP_3215	9.97e-185	529.0	2DBF1@1|root,2Z8VU@2|Bacteria,1MV31@1224|Proteobacteria,1RSDF@1236|Gammaproteobacteria,46AZK@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	CRISPR-associated protein (Cas_Csy1)	csy1	-	-	ko:K19127	-	-	-	-	ko00000,ko02048	-	-	-	Cas_Csy1
k141_5161_23	1319815.HMPREF0202_02853	7.61e-109	324.0	COG0675@1|root,COG0675@2|Bacteria,379SD@32066|Fusobacteria	32066|Fusobacteria	L	transposase IS891 IS1136 IS1341 family	-	-	-	ko:K07496	-	-	-	-	ko00000	-	-	-	HTH_OrfB_IS605,OrfB_IS605,OrfB_Zn_ribbon
k141_3171_1	1121396.KB892900_gene2110	2.34e-217	611.0	COG0427@1|root,COG0427@2|Bacteria,1MUGE@1224|Proteobacteria,42MHC@68525|delta/epsilon subdivisions,2WINZ@28221|Deltaproteobacteria,2MI0T@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Acetyl-CoA hydrolase/transferase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	iAF987.Gmet_3304	AcetylCoA_hyd_C,AcetylCoA_hydro,Acetyltransf_1
k141_3171_2	1304885.AUEY01000017_gene3716	3.32e-302	839.0	COG1960@1|root,COG1960@2|Bacteria,1MU20@1224|Proteobacteria,42N2H@68525|delta/epsilon subdivisions,2WMIR@28221|Deltaproteobacteria,2MIIF@213118|Desulfobacterales	28221|Deltaproteobacteria	I	Acyl-CoA dehydrogenase N terminal	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_C,Acyl-CoA_dh_M,Acyl-CoA_dh_N,AcylCoA_DH_N
k141_3171_3	1487923.DP73_04745	3.62e-105	311.0	arCOG10401@1|root,2ZA7Y@2|Bacteria,1V3TD@1239|Firmicutes,24F9C@186801|Clostridia,264MB@186807|Peptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_3171_4	879212.DespoDRAFT_00847	3.8e-206	582.0	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,42MSR@68525|delta/epsilon subdivisions,2WIXG@28221|Deltaproteobacteria,2MIJC@213118|Desulfobacterales	28221|Deltaproteobacteria	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
k141_3171_5	1121403.AUCV01000007_gene1195	1.37e-75	263.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42P9M@68525|delta/epsilon subdivisions,2WMKW@28221|Deltaproteobacteria,2MIX0@213118|Desulfobacterales	28221|Deltaproteobacteria	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal,dCache_3
k141_3171_6	1304883.KI912532_gene1857	6.76e-20	93.6	COG0642@1|root,COG2203@1|root,COG2703@1|root,COG0642@2|Bacteria,COG2203@2|Bacteria,COG2703@2|Bacteria,1RGKE@1224|Proteobacteria,2WHKS@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,Hpt,Response_reg
k141_4574_1	573370.DMR_06490	1.22e-59	190.0	COG0454@1|root,COG0454@2|Bacteria,1RD5R@1224|Proteobacteria	1224|Proteobacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
k141_4574_2	160799.PBOR_08755	3.71e-116	353.0	28IEQ@1|root,2Z8GQ@2|Bacteria,1UNXS@1239|Firmicutes,4HTNH@91061|Bacilli,26SDW@186822|Paenibacillaceae	91061|Bacilli	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_1839_1	247633.GP2143_15366	3.64e-155	456.0	COG1012@1|root,COG1012@2|Bacteria,1QUBI@1224|Proteobacteria,1T3J1@1236|Gammaproteobacteria,1J58I@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	COG1012 NAD-dependent aldehyde dehydrogenases	-	-	1.1.1.1,1.2.1.10,1.2.1.87	ko:K04072,ko:K13922	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00640,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00640,map00650,map01100,map01110,map01120,map01130,map01220	-	R00228,R00623,R00754,R01172,R04880,R05233,R05234,R06917,R06927,R09097	RC00004,RC00050,RC00088,RC00099,RC00116,RC00184,RC00649,RC01195	ko00000,ko00001,ko01000	-	-	-	Aldedh
k141_1839_2	945543.VIBR0546_05389	3.03e-170	480.0	COG0157@1|root,COG0157@2|Bacteria,1MW0C@1224|Proteobacteria,1RMBU@1236|Gammaproteobacteria,1XTQ3@135623|Vibrionales	135623|Vibrionales	H	Belongs to the NadC ModD family	nadC	-	2.4.2.19	ko:K00767	ko00760,ko01100,map00760,map01100	M00115	R03348	RC02877	ko00000,ko00001,ko00002,ko01000	-	-	-	QRPTase_C,QRPTase_N
k141_1839_3	312309.VF_2183	1.83e-92	274.0	COG3023@1|root,COG3023@2|Bacteria,1RDHU@1224|Proteobacteria,1S3PG@1236|Gammaproteobacteria,1XTXJ@135623|Vibrionales	135623|Vibrionales	V	COG3023 Negative regulator of beta-lactamase expression	ampD	-	3.5.1.28	ko:K03806	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	Amidase_2
k141_1839_4	1238450.VIBNISOn1_1920030	1.09e-102	299.0	COG0716@1|root,COG0716@2|Bacteria,1QRBW@1224|Proteobacteria,1RMED@1236|Gammaproteobacteria,1XSJG@135623|Vibrionales	135623|Vibrionales	C	Low-potential electron donor to a number of redox enzymes	fldB	-	-	ko:K03840	-	-	-	-	ko00000	-	-	-	Flavodoxin_1
k141_1839_5	1219065.VPR01S_09_01540	9.86e-177	497.0	COG4974@1|root,COG4974@2|Bacteria,1MVNF@1224|Proteobacteria,1RPI8@1236|Gammaproteobacteria,1XT87@135623|Vibrionales	135623|Vibrionales	D	recombinase XerD	xerD	GO:0000150,GO:0003674,GO:0003824,GO:0006139,GO:0006259,GO:0006310,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009009,GO:0009987,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140097,GO:1901360	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
k141_1839_6	675806.VII_001447	7.98e-100	298.0	COG1651@1|root,COG1651@2|Bacteria,1RD39@1224|Proteobacteria,1S3U8@1236|Gammaproteobacteria,1XSD4@135623|Vibrionales	135623|Vibrionales	O	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process	dsbC	-	5.3.4.1	ko:K03981	-	-	-	-	ko00000,ko01000,ko02044,ko03110	3.A.7.11.1	-	-	DsbC_N,Thioredoxin_2
k141_1839_7	29495.EA26_03430	0.0	965.0	COG0608@1|root,COG0608@2|Bacteria,1MU1M@1224|Proteobacteria,1RMF4@1236|Gammaproteobacteria,1XTR9@135623|Vibrionales	135623|Vibrionales	L	exonuclease recj	recJ	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
k141_1839_8	1219065.VPR01S_09_01510	2.06e-136	391.0	COG2186@1|root,COG2186@2|Bacteria,1MUP9@1224|Proteobacteria,1RNPJ@1236|Gammaproteobacteria,1XV1H@135623|Vibrionales	135623|Vibrionales	K	COG2186 Transcriptional regulators	pdhR	-	-	ko:K05799	-	-	-	-	ko00000,ko03000	-	-	-	FCD,GntR
k141_1839_9	1219076.N646_1612	0.0	1659.0	COG2609@1|root,COG2609@2|Bacteria,1MV21@1224|Proteobacteria,1RN6K@1236|Gammaproteobacteria,1XU1V@135623|Vibrionales	135623|Vibrionales	C	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	aceE	-	1.2.4.1	ko:K00163	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
k141_1839_10	1219065.VPR01S_09_01490	1.03e-288	803.0	COG0508@1|root,COG0508@2|Bacteria,1MU7K@1224|Proteobacteria,1RNPT@1236|Gammaproteobacteria,1XT8J@135623|Vibrionales	135623|Vibrionales	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	aceF	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
k141_3849_1	55601.VANGNB10_cII0535	2.35e-70	228.0	COG1196@1|root,COG3593@1|root,COG1196@2|Bacteria,COG3593@2|Bacteria,1N2CB@1224|Proteobacteria,1RQN2@1236|Gammaproteobacteria,1XSQI@135623|Vibrionales	135623|Vibrionales	L	ATP-dependent endonuclease of the OLD family	ybjD	-	-	ko:K07459	-	-	-	-	ko00000	-	-	-	DUF2813
k141_3849_2	1219077.VAZ01S_085_00330	1e-68	226.0	COG0737@1|root,COG0737@2|Bacteria,1MX03@1224|Proteobacteria,1RPX3@1236|Gammaproteobacteria,1XU8U@135623|Vibrionales	135623|Vibrionales	F	Belongs to the 5'-nucleotidase family	-	-	3.1.3.5	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	5_nucleotid_C,Metallophos
k141_4575_1	870187.Thini_2463	2.21e-16	80.1	COG1752@1|root,COG1752@2|Bacteria,1MUM9@1224|Proteobacteria,1RRA1@1236|Gammaproteobacteria,460S1@72273|Thiotrichales	72273|Thiotrichales	S	Patatin-like phospholipase	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
k141_5162_1	522772.Dacet_0122	5.69e-114	350.0	COG2274@1|root,COG2274@2|Bacteria	2|Bacteria	V	protein secretion by the type I secretion system	lapB	-	-	ko:K12541	ko02010,map02010	M00330	-	-	ko00000,ko00001,ko00002,ko02000,ko02044	3.A.1.109.3,3.A.1.109.4	-	-	ABC_membrane,ABC_tran,Peptidase_C39
k141_4576_1	1079460.ATTQ01000060_gene896	2.11e-70	222.0	COG3246@1|root,COG3246@2|Bacteria,1MZTP@1224|Proteobacteria,2TQKN@28211|Alphaproteobacteria,4B9QZ@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	beta-keto acid cleavage enzyme	-	-	-	-	-	-	-	-	-	-	-	-	BKACE
k141_2148_1	1423732.BALS01000021_gene315	1.85e-17	82.4	COG3697@1|root,COG3697@2|Bacteria,1VB3E@1239|Firmicutes,4HMZ5@91061|Bacilli,3F74S@33958|Lactobacillaceae	91061|Bacilli	HI	Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase	citX	-	2.7.7.61	ko:K05964	ko02020,map02020	-	R10706	-	ko00000,ko00001,ko01000	-	-	-	CitX
k141_2148_2	243277.VC_0799	5.74e-279	774.0	COG3051@1|root,COG3051@2|Bacteria,1MYI9@1224|Proteobacteria,1RQ32@1236|Gammaproteobacteria,1XWG2@135623|Vibrionales	135623|Vibrionales	H	Citrate lyase, alpha subunit (CitF)	citF	-	2.8.3.10	ko:K01643	ko02020,map02020	-	R00362	RC00067,RC01118	ko00000,ko00001,ko01000	-	-	-	CitF
k141_2148_3	675806.VII_002967	8.74e-170	478.0	COG2301@1|root,COG2301@2|Bacteria,1MW0A@1224|Proteobacteria,1RNEJ@1236|Gammaproteobacteria,1XWD6@135623|Vibrionales	135623|Vibrionales	G	Belongs to the HpcH HpaI aldolase family	citE	-	4.1.3.34	ko:K01644	ko02020,map02020	-	R00362	RC00067,RC01118	ko00000,ko00001,ko01000	-	-	-	HpcH_HpaI
k141_2148_4	758.BBIX01000009_gene1823	8.69e-30	108.0	COG3052@1|root,COG3052@2|Bacteria,1N80A@1224|Proteobacteria,1SF09@1236|Gammaproteobacteria,1Y917@135625|Pasteurellales	135625|Pasteurellales	C	Covalent carrier of the coenzyme of citrate lyase	citD	-	-	ko:K01646	ko02020,map02020	-	R00362	RC00067,RC01118	ko00000,ko00001	-	-	-	ACP
k141_2148_5	1116375.VEJY3_17151	2.83e-126	373.0	COG3053@1|root,COG3053@2|Bacteria,1NGEJ@1224|Proteobacteria,1RMMV@1236|Gammaproteobacteria,1XUSH@135623|Vibrionales	135623|Vibrionales	H	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase	citC	-	6.2.1.22	ko:K01910	ko02020,map02020	-	R04449	RC00012,RC00039	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_10,Citrate_ly_lig
k141_2148_6	1116375.VEJY3_17146	1.28e-252	701.0	COG3493@1|root,COG3493@2|Bacteria,1NKCA@1224|Proteobacteria,1RN6E@1236|Gammaproteobacteria,1XUGC@135623|Vibrionales	135623|Vibrionales	C	2-hydroxycarboxylate transporter family	-	-	-	-	-	-	-	-	-	-	-	-	2HCT
k141_2148_7	1116375.VEJY3_17141	2.36e-15	71.6	COG3630@1|root,COG3630@2|Bacteria,1NHYS@1224|Proteobacteria,1SGS8@1236|Gammaproteobacteria,1XZBR@135623|Vibrionales	135623|Vibrionales	C	Lyase and sodium transporter	-	GO:0003674,GO:0003824,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008150,GO:0008948,GO:0015672,GO:0016829,GO:0016830,GO:0016831,GO:0030001,GO:0051179,GO:0051234	4.1.1.3	ko:K01573	ko00620,ko01100,map00620,map01100	-	R00217	RC00040	ko00000,ko00001,ko01000,ko02000	3.B.1.1.1	-	-	OAD_gamma
k141_2148_8	298386.PBPRA2298	1.69e-310	860.0	COG0511@1|root,COG5016@1|root,COG0511@2|Bacteria,COG5016@2|Bacteria,1QTTG@1224|Proteobacteria,1RNG6@1236|Gammaproteobacteria,1XSDJ@135623|Vibrionales	135623|Vibrionales	CI	Conserved carboxylase domain	oadA-2	-	4.1.1.3	ko:K01571	ko00620,ko01100,map00620,map01100	-	R00217	RC00040	ko00000,ko00001,ko01000,ko02000	3.B.1.1.1	-	-	Biotin_lipoyl,HMGL-like,PYC_OADA
k141_2148_9	243277.VC_0792	6.98e-252	698.0	COG1883@1|root,COG1883@2|Bacteria,1MV0G@1224|Proteobacteria,1RP3W@1236|Gammaproteobacteria,1XW5U@135623|Vibrionales	135623|Vibrionales	C	Na+-transporting oxaloacetate decarboxylase beta subunit	oadB-2	GO:0003674,GO:0003824,GO:0006091,GO:0006113,GO:0008150,GO:0008152,GO:0008948,GO:0009987,GO:0015980,GO:0016829,GO:0016830,GO:0016831,GO:0044237,GO:0055114	4.1.1.3	ko:K01572	ko00620,ko01100,map00620,map01100	-	R00217	RC00040	ko00000,ko00001,ko01000,ko02000	3.B.1.1.1	-	-	OAD_beta
k141_2148_10	243277.VC_0791	1.87e-243	687.0	COG3290@1|root,COG3290@2|Bacteria,1MXQ5@1224|Proteobacteria,1RNRF@1236|Gammaproteobacteria,1XSAU@135623|Vibrionales	135623|Vibrionales	T	COG3290 Signal transduction histidine kinase regulating citrate malate metabolism	citA	-	2.7.13.3	ko:K07700	ko02020,map02020	M00486	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,SPOB_a,sCache_3_2
k141_2148_11	675806.VII_002975	5.1e-109	319.0	COG4565@1|root,COG4565@2|Bacteria,1P6VJ@1224|Proteobacteria,1RPI7@1236|Gammaproteobacteria,1Y2MJ@135623|Vibrionales	135623|Vibrionales	K	Transcriptional regulator	-	-	-	ko:K02475,ko:K07702	ko02020,map02020	M00486	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	CitT,Response_reg
k141_2148_13	595494.Tola_1659	9.65e-43	145.0	COG2050@1|root,COG2050@2|Bacteria,1N1FK@1224|Proteobacteria,1SBSR@1236|Gammaproteobacteria,1Y5ZP@135624|Aeromonadales	135624|Aeromonadales	Q	PFAM thioesterase superfamily protein	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
k141_2148_14	1283284.AZUK01000002_gene2836	2.27e-32	120.0	COG1433@1|root,COG1433@2|Bacteria,1N8TZ@1224|Proteobacteria,1SAUB@1236|Gammaproteobacteria,1Y61X@135624|Aeromonadales	135624|Aeromonadales	S	Dinitrogenase iron-molybdenum cofactor	-	-	-	-	-	-	-	-	-	-	-	-	Nitro_FeMo-Co
k141_2148_15	595494.Tola_1661	1.92e-43	143.0	COG1342@1|root,COG1342@2|Bacteria,1N80T@1224|Proteobacteria,1S9DC@1236|Gammaproteobacteria,1Y5UZ@135624|Aeromonadales	135624|Aeromonadales	S	Belongs to the UPF0251 family	-	-	-	-	-	-	-	-	-	-	-	-	DUF134
k141_2148_16	298386.PBPRB1958	4.23e-98	297.0	COG0679@1|root,COG0679@2|Bacteria,1P2SH@1224|Proteobacteria,1S7N5@1236|Gammaproteobacteria,1XTMY@135623|Vibrionales	135623|Vibrionales	S	Membrane transport protein	VV2066	-	-	ko:K07088	-	-	-	-	ko00000	-	-	-	Mem_trans
k141_2148_17	926550.CLDAP_38440	8.29e-47	164.0	COG0657@1|root,COG0657@2|Bacteria,2G8DI@200795|Chloroflexi	200795|Chloroflexi	I	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6,Peptidase_S9
k141_2148_18	457421.CBFG_04739	2.72e-18	81.6	2E6H5@1|root,3314C@2|Bacteria,1VH2I@1239|Firmicutes,24P98@186801|Clostridia	186801|Clostridia	S	Protein of unknown function (DUF2809)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2809
k141_4893_1	1141106.CAIB01000016_gene122	8.44e-71	244.0	COG4166@1|root,COG4166@2|Bacteria,1TNYQ@1239|Firmicutes,4HAMK@91061|Bacilli,4GWY5@90964|Staphylococcaceae	91061|Bacilli	E	ABC transporter substrate-binding protein	oppA	-	-	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	SBP_bac_5
k141_4893_2	985762.SAGN_08083	4.33e-95	290.0	COG0601@1|root,COG0601@2|Bacteria,1TP1S@1239|Firmicutes,4HA2S@91061|Bacilli,4GYK4@90964|Staphylococcaceae	91061|Bacilli	P	COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components	oppB	-	-	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1
k141_4893_3	1385510.N781_15360	1.1e-112	341.0	COG1173@1|root,COG1173@2|Bacteria,1TP4R@1239|Firmicutes,4H9PZ@91061|Bacilli,2Y8RZ@289201|Pontibacillus	91061|Bacilli	U	Peptide ABC transporter permease	oppC	-	-	ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1,OppC_N
k141_4893_4	1246484.D479_15787	6.42e-166	473.0	COG0444@1|root,COG0444@2|Bacteria,1TP6E@1239|Firmicutes,4HA4E@91061|Bacilli,3NE36@45667|Halobacillus	91061|Bacilli	EP	Oligopeptide/dipeptide transporter, C-terminal region	oppD	-	-	ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
k141_4893_5	1301100.HG529378_gene4074	1.32e-156	447.0	COG4608@1|root,COG4608@2|Bacteria,1V36J@1239|Firmicutes,24C3R@186801|Clostridia,36EGD@31979|Clostridiaceae	186801|Clostridia	P	Belongs to the ABC transporter superfamily	oppF	-	-	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
k141_4893_6	1499689.CCNN01000007_gene2186	1.2e-208	599.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,1TSSC@1239|Firmicutes,248I6@186801|Clostridia,36EW0@31979|Clostridiaceae	186801|Clostridia	C	pyruvate flavodoxin ferredoxin oxidoreductase domain protein	korA	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR,POR_N
k141_4893_7	457396.CSBG_00933	5.68e-113	334.0	COG1013@1|root,COG1013@2|Bacteria,1TQJ2@1239|Firmicutes,25CAJ@186801|Clostridia,36WSB@31979|Clostridiaceae	186801|Clostridia	C	PFAM thiamine pyrophosphate protein domain protein TPP-binding	korB	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFO_beta_C,TPP_enzyme_C
k141_4893_8	1280689.AUJC01000013_gene1776	1.84e-265	769.0	COG1221@1|root,COG3933@1|root,COG1221@2|Bacteria,COG3933@2|Bacteria,1VSHE@1239|Firmicutes,248QH@186801|Clostridia,36ECX@31979|Clostridiaceae	186801|Clostridia	K	system, fructose subfamily, IIA component	-	-	-	-	-	-	-	-	-	-	-	-	EIIA-man,PRD,Sigma54_activat,TrmB
k141_4893_9	171693.BN988_03173	1.2e-25	99.0	COG1440@1|root,COG1440@2|Bacteria,1VADE@1239|Firmicutes,4HKCQ@91061|Bacilli,23KXS@182709|Oceanobacillus	91061|Bacilli	G	PTS system, Lactose/Cellobiose specific IIB subunit	ydhM	-	2.7.1.196,2.7.1.205	ko:K02760	ko00500,ko02060,map00500,map02060	M00275	R11170,R11172	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.3.2	-	-	PTS_IIB
k141_4893_10	1094508.Tsac_0114	2.24e-176	506.0	COG1455@1|root,COG1455@2|Bacteria,1TP8D@1239|Firmicutes,24808@186801|Clostridia,42HZE@68295|Thermoanaerobacterales	186801|Clostridia	G	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane	-	-	-	ko:K02761	ko00500,ko02060,map00500,map02060	M00275	R11170,R11172	RC00017,RC03206	ko00000,ko00001,ko00002,ko02000	4.A.3.2	-	-	PTS_EIIC
k141_4893_11	985665.HPL003_00930	7.31e-26	100.0	COG1447@1|root,COG1447@2|Bacteria,1VEGE@1239|Firmicutes,4HM37@91061|Bacilli,26Y4J@186822|Paenibacillaceae	91061|Bacilli	G	PTS system, Lactose/Cellobiose specific IIA subunit	licA	-	2.7.1.196,2.7.1.205	ko:K02759	ko00500,ko02060,map00500,map02060	M00275	R11170,R11172	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.3.2	-	iYO844.BSU38570	PTS_IIA
k141_4893_12	555079.Toce_0345	1.36e-144	426.0	COG1486@1|root,COG1486@2|Bacteria,1TQ9I@1239|Firmicutes,24995@186801|Clostridia,42FX4@68295|Thermoanaerobacterales	186801|Clostridia	G	PFAM glycoside hydrolase, family 4	-	-	3.2.1.86	ko:K01222	ko00010,ko00500,map00010,map00500	-	R00839,R05133,R05134	RC00049,RC00171,RC00714	ko00000,ko00001,ko01000	-	GT4	-	Glyco_hydro_4,Glyco_hydro_4C
k141_4893_13	632245.CLP_0291	1.02e-147	428.0	COG3589@1|root,COG3589@2|Bacteria,1TRIY@1239|Firmicutes,248R7@186801|Clostridia,36EAB@31979|Clostridiaceae	186801|Clostridia	S	hmm pf05913	-	-	-	ko:K09963	-	-	-	-	ko00000	-	-	-	DUF871
k141_4893_14	37659.JNLN01000001_gene804	4.92e-19	99.0	COG2898@1|root,COG2898@2|Bacteria,1U5FR@1239|Firmicutes,248XI@186801|Clostridia,36E5R@31979|Clostridiaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane,ABC_tran_2
k141_4893_15	1196322.A370_01507	7.41e-87	264.0	COG1131@1|root,COG1131@2|Bacteria,1TQIH@1239|Firmicutes,248WG@186801|Clostridia,36DUF@31979|Clostridiaceae	186801|Clostridia	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
k141_4893_16	665571.STHERM_c15110	3.89e-38	144.0	COG0697@1|root,COG0697@2|Bacteria,2J5K6@203691|Spirochaetes	203691|Spirochaetes	EG	EamA-like transporter family	ybfH	-	-	-	-	-	-	-	-	-	-	-	EamA
k141_4893_17	1321778.HMPREF1982_00754	7.26e-84	268.0	COG0013@1|root,COG0013@2|Bacteria,1TSBZ@1239|Firmicutes,249VN@186801|Clostridia,26BE8@186813|unclassified Clostridiales	186801|Clostridia	J	Threonine alanine tRNA ligase second additional domain protein	alaXL	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
k141_4893_18	1319815.HMPREF0202_02494	2.98e-190	539.0	COG1301@1|root,COG1301@2|Bacteria,3794D@32066|Fusobacteria	32066|Fusobacteria	C	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family	-	-	-	-	-	-	-	-	-	-	-	-	SDF
k141_4893_19	1121289.JHVL01000039_gene3135	1.62e-53	174.0	COG0348@1|root,COG0348@2|Bacteria,1UHUA@1239|Firmicutes,24BED@186801|Clostridia,36W8I@31979|Clostridiaceae	186801|Clostridia	C	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_5
k141_4893_21	1487921.DP68_14285	1.46e-53	187.0	COG4872@1|root,COG4872@2|Bacteria,1TT9X@1239|Firmicutes,24CCI@186801|Clostridia,36GUK@31979|Clostridiaceae	186801|Clostridia	S	Predicted membrane protein (DUF2157)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2157
k141_4893_23	1121324.CLIT_11c02470	9.47e-191	537.0	COG0468@1|root,COG0468@2|Bacteria,1TPD5@1239|Firmicutes,247SF@186801|Clostridia,25QH2@186804|Peptostreptococcaceae	186801|Clostridia	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	-	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
k141_4893_24	445973.CLOBAR_02146	1.31e-228	646.0	COG1418@1|root,COG1418@2|Bacteria,1TP48@1239|Firmicutes,248G8@186801|Clostridia,25R0R@186804|Peptostreptococcaceae	186801|Clostridia	S	Endoribonuclease that initiates mRNA decay	rny	-	-	ko:K18682	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DUF3552,HD,KH_1
k141_4893_26	1292035.H476_1861	1.76e-91	276.0	COG1179@1|root,COG1179@2|Bacteria,1TQ7A@1239|Firmicutes,248RA@186801|Clostridia,25R6Y@186804|Peptostreptococcaceae	186801|Clostridia	H	ThiF family	-	-	-	ko:K22132	-	-	-	-	ko00000,ko03016	-	-	-	ThiF
k141_4893_27	1158612.I580_00698	4.95e-25	112.0	COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,1TS9U@1239|Firmicutes,4H9M4@91061|Bacilli,4AZQ0@81852|Enterococcaceae	91061|Bacilli	S	Competence protein	comEC	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131,Lactamase_B
k141_4893_28	1408823.AXUS01000003_gene502	3.41e-116	343.0	COG4866@1|root,COG4866@2|Bacteria,1TR2J@1239|Firmicutes,2480E@186801|Clostridia,25QVR@186804|Peptostreptococcaceae	186801|Clostridia	S	Uncharacterised conserved protein (DUF2156)	-	-	-	ko:K01163	-	-	-	-	ko00000	-	-	-	DUF2156
k141_4893_29	500633.CLOHIR_02033	3.96e-85	271.0	COG4552@1|root,COG4552@2|Bacteria,1TRPM@1239|Firmicutes,24AP4@186801|Clostridia,25RCF@186804|Peptostreptococcaceae	186801|Clostridia	S	Sterol carrier protein domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_9,SCP2_2
k141_4893_30	1292035.H476_0719	1.01e-43	149.0	COG4720@1|root,COG4720@2|Bacteria,1TTCZ@1239|Firmicutes,25MT7@186801|Clostridia,25TDE@186804|Peptostreptococcaceae	186801|Clostridia	S	ECF-type riboflavin transporter, S component	-	-	-	-	-	-	-	-	-	-	-	-	ECF-ribofla_trS
k141_3850_1	96561.Dole_2812	9.99e-11	72.4	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42N5C@68525|delta/epsilon subdivisions,2WM18@28221|Deltaproteobacteria,2MIV1@213118|Desulfobacterales	28221|Deltaproteobacteria	T	PFAM ATP-binding region ATPase domain protein	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,PAS,PAS_9,Response_reg
k141_1153_1	489825.LYNGBM3L_21990	0.0	1049.0	COG1020@1|root,COG3321@1|root,COG1020@2|Bacteria,COG3321@2|Bacteria,1FZXE@1117|Cyanobacteria,1H927@1150|Oscillatoriales	1117|Cyanobacteria	Q	Acyl transferase domain in polyketide synthase (PKS) enzymes.	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N_2,AMP-binding,AMP-binding_C,Acyl_transf_1,Condensation,KAsynt_C_assoc,KR,Ketoacyl-synt_C,Methyltransf_12,PP-binding,PS-DH,Thioesterase,ketoacyl-synt
k141_2149_1	574966.KB898647_gene2635	9.26e-22	98.6	COG1518@1|root,COG1518@2|Bacteria,1MUKK@1224|Proteobacteria,1RNYK@1236|Gammaproteobacteria,1XMM2@135619|Oceanospirillales	135619|Oceanospirillales	L	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette	cas1	-	-	ko:K15342	-	-	-	-	ko00000,ko02048,ko03400	-	-	-	Cas_Cas1
k141_2149_2	313628.LNTAR_25305	3.56e-25	108.0	COG3344@1|root,COG3344@2|Bacteria	2|Bacteria	L	reverse transcriptase	-	-	2.7.7.49	ko:K00986	-	-	-	-	ko00000,ko01000	-	-	-	GIIM,RVT_1
k141_3173_2	743722.Sph21_4424	4e-06	48.1	COG1708@1|root,COG1708@2|Bacteria,4NMIA@976|Bacteroidetes,1ISV1@117747|Sphingobacteriia	976|Bacteroidetes	S	nucleotidyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Adenyl_transf
k141_3173_3	1496688.ER33_14740	8.21e-40	142.0	COG1708@1|root,COG1708@2|Bacteria	2|Bacteria	S	nucleotidyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Adenyl_transf,NTP_transf_2
k141_3173_4	1202962.KB907150_gene1933	2.49e-26	101.0	COG1247@1|root,COG1247@2|Bacteria,1R9WS@1224|Proteobacteria,1S20F@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
k141_5163_1	387093.SUN_0164	2.08e-07	55.1	COG0703@1|root,COG0703@2|Bacteria,1MUFJ@1224|Proteobacteria,42RJW@68525|delta/epsilon subdivisions,2YP85@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate	aroK	-	2.7.1.71	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	SKI
k141_5163_2	933262.AXAM01000043_gene1202	1.28e-143	417.0	COG0082@1|root,COG0082@2|Bacteria,1MU98@1224|Proteobacteria,42MF9@68525|delta/epsilon subdivisions,2WJ57@28221|Deltaproteobacteria,2MJ56@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	-	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_synt
k141_5163_3	419665.Maeo_1024	9.51e-39	146.0	COG0722@1|root,arCOG00245@2157|Archaea,2XU8C@28890|Euryarchaeota,23QJN@183939|Methanococci	183939|Methanococci	E	prephenate dehydrogenase	-	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006520,GO:0006570,GO:0006571,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008977,GO:0009058,GO:0009072,GO:0009073,GO:0009095,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019438,GO:0019752,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0070403,GO:0071704,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.3.1.12	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00025	R01728	RC00125	ko00000,ko00001,ko00002,ko01000	-	-	-	FDX-ACB,PDH
k141_4894_2	1304885.AUEY01000066_gene1300	1.22e-29	114.0	2E0IJ@1|root,32W47@2|Bacteria,1N1SH@1224|Proteobacteria,42TPQ@68525|delta/epsilon subdivisions,2WQMQ@28221|Deltaproteobacteria,2MKIF@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_4894_3	1121396.KB893070_gene1354	1.07e-24	111.0	COG0550@1|root,COG0551@1|root,COG0550@2|Bacteria,COG0551@2|Bacteria,1R8Y5@1224|Proteobacteria,42NAP@68525|delta/epsilon subdivisions,2WM76@28221|Deltaproteobacteria,2MIVR@213118|Desulfobacterales	28221|Deltaproteobacteria	L	DNA topoisomerase type I activity	-	-	-	-	-	-	-	-	-	-	-	-	zf-C4_Topoisom
k141_2447_3	1121434.AULY01000007_gene1356	2.64e-153	444.0	COG0019@1|root,COG0019@2|Bacteria,1MW3T@1224|Proteobacteria,42MVP@68525|delta/epsilon subdivisions,2WITG@28221|Deltaproteobacteria,2M7Z2@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	Belongs to the Orn Lys Arg decarboxylase class-II family. NspC subfamily	nspC	-	4.1.1.96	ko:K13747	ko00330,ko01100,map00330,map01100	-	R09081,R09082	RC00299	ko00000,ko00001,ko01000	-	-	-	Ala_racemase_N,Orn_DAP_Arg_deC
k141_2447_4	177437.HRM2_01390	4.4e-99	299.0	COG0010@1|root,COG0010@2|Bacteria,1MVFH@1224|Proteobacteria,42NBC@68525|delta/epsilon subdivisions,2WIMR@28221|Deltaproteobacteria,2MIAP@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Belongs to the arginase family	speB	-	3.5.3.1,3.5.3.11	ko:K01476,ko:K01480	ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146	M00029,M00133,M00134	R00551,R01157	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
k141_3186_1	1347392.CCEZ01000007_gene2015	2.06e-21	89.0	COG2344@1|root,COG2344@2|Bacteria,1TSMR@1239|Firmicutes,247RQ@186801|Clostridia,36EUI@31979|Clostridiaceae	186801|Clostridia	K	Modulates transcription in response to changes in cellular NADH NAD( ) redox state	rex	-	-	ko:K01926	-	-	-	-	ko00000,ko03000	-	-	-	CoA_binding,Put_DNA-bind_N
k141_5178_1	1121405.dsmv_1576	1.56e-15	75.9	COG4123@1|root,COG4123@2|Bacteria,1MXEQ@1224|Proteobacteria,42SAA@68525|delta/epsilon subdivisions,2WPCM@28221|Deltaproteobacteria,2MJTD@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Methyltransferase small domain	-	-	2.1.1.223	ko:K15460	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	MTS,Methyltransf_31
k141_5178_2	404380.Gbem_3436	3.21e-19	84.3	COG5512@1|root,COG5512@2|Bacteria,1N6KK@1224|Proteobacteria,42TK4@68525|delta/epsilon subdivisions,2WQQS@28221|Deltaproteobacteria,43VF7@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF721)	-	-	-	-	-	-	-	-	-	-	-	-	DUF721
k141_4182_1	1122207.MUS1_11620	3.41e-266	739.0	COG3333@1|root,COG3333@2|Bacteria,1MUKR@1224|Proteobacteria,1RMQB@1236|Gammaproteobacteria,1XIF1@135619|Oceanospirillales	135619|Oceanospirillales	S	Tripartite tricarboxylate transporter TctA family	-	-	-	ko:K07793	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.80.1	-	-	TctA
k141_4182_2	1232683.ADIMK_0105	2.13e-28	110.0	2E4UV@1|root,32ZP8@2|Bacteria,1N4X4@1224|Proteobacteria,1SER2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Tripartite tricarboxylate transporter TctB family	-	-	-	-	-	-	-	-	-	-	-	-	TctB
k141_4499_5	1348635.BBJY01000001_gene2466	3.03e-60	191.0	COG1433@1|root,COG1433@2|Bacteria,1RD9P@1224|Proteobacteria,1S50W@1236|Gammaproteobacteria,1Y0WD@135623|Vibrionales	135623|Vibrionales	S	Dinitrogenase iron-molybdenum cofactor	-	-	-	ko:K02596	-	-	-	-	ko00000	-	-	-	Nitro_FeMo-Co
k141_4499_6	156889.Mmc1_1191	2.35e-25	97.4	COG1143@1|root,COG1143@2|Bacteria,1N1SG@1224|Proteobacteria	1224|Proteobacteria	C	PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein	fdxB	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_21,Fer4_4,Fer4_7,Fer4_9
k141_4129_1	575788.VS_1100	1.75e-75	237.0	COG4067@1|root,COG4067@2|Bacteria,1N0VV@1224|Proteobacteria,1SZUE@1236|Gammaproteobacteria,1XU7F@135623|Vibrionales	135623|Vibrionales	O	protein conserved in archaea	-	-	-	-	-	-	-	-	-	-	-	-	Zn_protease
k141_4129_2	945550.VISI1226_09224	1.36e-16	78.6	COG1305@1|root,COG1305@2|Bacteria,1MVV3@1224|Proteobacteria,1RRIA@1236|Gammaproteobacteria,1XSMI@135623|Vibrionales	135623|Vibrionales	E	7 transmembrane helices usually fused to an inactive transglutaminase	-	-	-	-	-	-	-	-	-	-	-	-	7TM_transglut,Transglut_i_TM
k141_176_1	1121405.dsmv_1728	2.04e-74	233.0	COG2884@1|root,COG2884@2|Bacteria,1MVQ4@1224|Proteobacteria,42MAM@68525|delta/epsilon subdivisions,2WK4Y@28221|Deltaproteobacteria,2MJCE@213118|Desulfobacterales	28221|Deltaproteobacteria	D	PFAM ABC transporter	ftsE	-	-	ko:K09812	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	ABC_tran
k141_176_2	643648.Slip_1871	7.17e-28	116.0	COG2177@1|root,COG2177@2|Bacteria,1TPND@1239|Firmicutes,24AA6@186801|Clostridia,42JWR@68298|Syntrophomonadaceae	186801|Clostridia	D	Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation	ftsX	-	-	ko:K09811	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	FtsX
k141_176_3	933262.AXAM01000046_gene140	2.11e-64	223.0	COG4942@1|root,COG4942@2|Bacteria,1MY3E@1224|Proteobacteria,42N32@68525|delta/epsilon subdivisions,2WKBN@28221|Deltaproteobacteria,2MI0S@213118|Desulfobacterales	28221|Deltaproteobacteria	D	PFAM peptidase	-	-	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M23,SH3_3
k141_176_4	1304885.AUEY01000002_gene414	7.77e-94	291.0	COG0793@1|root,COG0793@2|Bacteria,1MU39@1224|Proteobacteria,42MHD@68525|delta/epsilon subdivisions,2WJKC@28221|Deltaproteobacteria,2MJ79@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Belongs to the peptidase S41A family	ctpA	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_S41
k141_177_1	933262.AXAM01000039_gene1167	2.26e-51	169.0	COG3605@1|root,COG3605@2|Bacteria,1RKM4@1224|Proteobacteria,42SPE@68525|delta/epsilon subdivisions,2WPDX@28221|Deltaproteobacteria,2MK9U@213118|Desulfobacterales	28221|Deltaproteobacteria	T	GAF domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2
k141_4501_1	1122197.ATWI01000008_gene2888	3.93e-191	558.0	COG0188@1|root,COG0188@2|Bacteria,1MURI@1224|Proteobacteria,1RMTC@1236|Gammaproteobacteria,464Q5@72275|Alteromonadaceae	1236|Gammaproteobacteria	L	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule	parC	GO:0000819,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006265,GO:0006276,GO:0006725,GO:0006807,GO:0006996,GO:0007049,GO:0007059,GO:0007062,GO:0008150,GO:0008152,GO:0009330,GO:0009987,GO:0016020,GO:0016043,GO:0019897,GO:0019898,GO:0022402,GO:0030541,GO:0032991,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0098813,GO:1901360,GO:1901363	-	ko:K02621	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
k141_4130_1	1224318.DT73_04280	1.78e-71	244.0	COG0834@1|root,COG2206@1|root,COG3437@1|root,COG0834@2|Bacteria,COG2206@2|Bacteria,COG3437@2|Bacteria,1MV37@1224|Proteobacteria,1RM9C@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	COG0840 Methyl-accepting chemotaxis protein	-	-	-	-	-	-	-	-	-	-	-	-	HD_5,SBP_bac_3,dCache_1
k141_4503_1	439235.Dalk_0610	2.86e-215	616.0	COG0281@1|root,COG0281@2|Bacteria,1MU0A@1224|Proteobacteria,42MDI@68525|delta/epsilon subdivisions,2WIVY@28221|Deltaproteobacteria,2MHYG@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM malic	-	-	1.1.1.38,1.1.1.40	ko:K00027,ko:K00029	ko00620,ko00710,ko01100,ko01120,ko01200,ko02020,map00620,map00710,map01100,map01120,map01200,map02020	M00169,M00172	R00214,R00216	RC00105	ko00000,ko00001,ko00002,ko01000	-	-	-	Malic_M,malic
k141_179_1	1278307.KB906975_gene1921	1.01e-63	233.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,2QIQ4@267894|Psychromonadaceae	1236|Gammaproteobacteria	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K03406,ko:K05875	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal,TarH,dCache_1
k141_180_1	55601.VANGNB10_cII0882c	4.18e-08	54.3	2AWP3@1|root,31NK0@2|Bacteria,1QKAN@1224|Proteobacteria,1TIE6@1236|Gammaproteobacteria,1XYYR@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_180_2	55601.VANGNB10_cII0878	3.76e-110	329.0	29HQP@1|root,304MY@2|Bacteria,1RFYR@1224|Proteobacteria,1RZH8@1236|Gammaproteobacteria,1XVI3@135623|Vibrionales	135623|Vibrionales	S	Domain of unknown function (DUF3541)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3541
k141_4505_1	1160707.AJIK01000046_gene1661	5.71e-163	472.0	COG3464@1|root,COG3464@2|Bacteria,1TQ93@1239|Firmicutes,4HC0Q@91061|Bacilli,26HF2@186818|Planococcaceae	91061|Bacilli	L	Transposase	-	-	-	ko:K07485	-	-	-	-	ko00000	-	-	-	DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3
k141_181_1	177439.DP2856	3.67e-59	187.0	COG0454@1|root,COG0456@2|Bacteria,1RAJC@1224|Proteobacteria,42WFD@68525|delta/epsilon subdivisions,2WS1W@28221|Deltaproteobacteria,2MMAH@213118|Desulfobacterales	28221|Deltaproteobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	ko:K03828	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_1
k141_4132_1	1485545.JQLW01000006_gene221	1.94e-17	81.3	COG0518@1|root,COG0518@2|Bacteria,1MUDH@1224|Proteobacteria	1224|Proteobacteria	F	Glutamine amido-transferase	-	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase
k141_4132_2	216142.LT40_20855	1.08e-16	87.8	COG2885@1|root,COG2885@2|Bacteria,1REH1@1224|Proteobacteria	1224|Proteobacteria	M	Belongs to the ompA family	uptE	-	-	-	-	-	-	-	-	-	-	-	DUF4398,OmpA
k141_2757_2	536227.CcarbDRAFT_3925	2.18e-101	317.0	COG2897@1|root,COG2897@2|Bacteria,1TS7E@1239|Firmicutes,24CNW@186801|Clostridia,36DJP@31979|Clostridiaceae	186801|Clostridia	P	domain protein	-	-	2.8.1.11	ko:K21028	ko04122,map04122	-	R07461	-	ko00000,ko00001,ko01000	-	-	-	Rhodanese
k141_2757_3	1511.CLOST_0529	2.7e-32	122.0	2BYUV@1|root,307Y4@2|Bacteria,1V64G@1239|Firmicutes,24K9A@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_2757_4	1230342.CTM_23779	4.37e-165	470.0	COG0010@1|root,COG0010@2|Bacteria,1TP2A@1239|Firmicutes,2493V@186801|Clostridia,36EJ8@31979|Clostridiaceae	186801|Clostridia	E	Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide	hutG	-	3.5.3.8	ko:K01479	ko00340,ko01100,map00340,map01100	M00045	R02285	RC00221,RC00681	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
k141_2757_5	469617.FUAG_01434	8.87e-246	696.0	COG0006@1|root,COG0006@2|Bacteria,379FB@32066|Fusobacteria	32066|Fusobacteria	E	Creatinase/Prolidase N-terminal domain	-	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Creatinase_N,Creatinase_N_2,Peptidase_M24,Peptidase_M24_C
k141_2757_6	929506.CbC4_2527	1.73e-46	162.0	COG5522@1|root,COG5522@2|Bacteria,1V4XE@1239|Firmicutes,24Q8V@186801|Clostridia,36KVT@31979|Clostridiaceae	186801|Clostridia	S	Integral membrane protein (intg_mem_TP0381)	-	-	-	-	-	-	-	-	-	-	-	-	Intg_mem_TP0381
k141_2757_7	545243.BAEV01000004_gene865	8.53e-77	252.0	COG0038@1|root,COG0038@2|Bacteria,1TPX0@1239|Firmicutes,247R4@186801|Clostridia,36FR4@31979|Clostridiaceae	186801|Clostridia	P	Chloride channel	-	-	-	ko:K03281	-	-	-	-	ko00000	2.A.49	-	-	CBS,Voltage_CLC
k141_2757_8	1319815.HMPREF0202_01332	6.79e-180	511.0	COG2309@1|root,COG2309@2|Bacteria,379GR@32066|Fusobacteria	32066|Fusobacteria	E	Thermophilic metalloprotease (M29)	-	-	-	ko:K19689	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M29
k141_2757_26	44251.PDUR_02870	8.37e-29	111.0	2AQIU@1|root,31FRM@2|Bacteria,1V721@1239|Firmicutes,4HJ29@91061|Bacilli,272M3@186822|Paenibacillaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_2757_28	293826.Amet_4170	3.61e-60	196.0	2EQ5N@1|root,33HRY@2|Bacteria,1VP67@1239|Firmicutes,24UWY@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_2757_30	1499689.CCNN01000006_gene415	2.84e-247	694.0	28HH2@1|root,2Z7ST@2|Bacteria,1UYQU@1239|Firmicutes,248KR@186801|Clostridia,36FIU@31979|Clostridiaceae	186801|Clostridia	M	Sulfhydryl-activated toxin that causes cytolysis by forming pores in cholesterol containing host membranes. After binding to target membranes, the protein undergoes a major conformation change, leading to its insertion in the host membrane and formation of an oligomeric pore complex	pfo	-	-	ko:K11031	ko02024,map02024	-	-	-	ko00000,ko00001,ko02042	-	-	-	Thiol_cytolys_C,Thiol_cytolysin
k141_2757_31	1118055.CAGU01000013_gene746	2.06e-200	570.0	COG0534@1|root,COG0534@2|Bacteria,1TPFM@1239|Firmicutes,247J9@186801|Clostridia,22GF0@1570339|Peptoniphilaceae	186801|Clostridia	V	MATE efflux family protein	-	-	-	-	-	-	-	-	-	-	-	-	MatE
k141_2757_32	908340.HMPREF9406_3901	5.39e-169	493.0	COG1129@1|root,COG1129@2|Bacteria,1TQRP@1239|Firmicutes,24YCF@186801|Clostridia,36UGY@31979|Clostridiaceae	186801|Clostridia	G	ABC transporter, ATP-binding protein	-	-	-	ko:K16786,ko:K16787	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ABC_tran
k141_2757_33	910313.HMPREF9320_0333	2.26e-74	233.0	COG0619@1|root,COG0619@2|Bacteria,1TTA6@1239|Firmicutes,4IPJ5@91061|Bacilli	91061|Bacilli	P	Cobalt transport protein	-	-	-	ko:K16785	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	CbiQ
k141_2102_3	1219072.VHA01S_074_00150	6.39e-115	337.0	COG3547@1|root,COG3547@2|Bacteria,1MUER@1224|Proteobacteria,1RMAQ@1236|Gammaproteobacteria,1XVPF@135623|Vibrionales	135623|Vibrionales	L	COG3547 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k141_2102_4	1219072.VHA01S_074_00150	3.72e-20	88.2	COG3547@1|root,COG3547@2|Bacteria,1MUER@1224|Proteobacteria,1RMAQ@1236|Gammaproteobacteria,1XVPF@135623|Vibrionales	135623|Vibrionales	L	COG3547 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k141_2102_5	945543.VIBR0546_20218	9.6e-13	67.0	COG3547@1|root,COG3547@2|Bacteria,1MUER@1224|Proteobacteria,1RMAQ@1236|Gammaproteobacteria,1XVPF@135623|Vibrionales	135623|Vibrionales	L	COG3547 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k141_2102_6	311402.Avi_3578	1.08e-58	184.0	COG3791@1|root,COG3791@2|Bacteria,1N031@1224|Proteobacteria,2UC7G@28211|Alphaproteobacteria,4BG5B@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Glutathione-dependent formaldehyde-activating enzyme	-	-	-	-	-	-	-	-	-	-	-	-	GFA
k141_2102_7	1219072.VHA01S_010_00870	2.36e-179	513.0	COG0513@1|root,COG0513@2|Bacteria,1R3PZ@1224|Proteobacteria,1RYNW@1236|Gammaproteobacteria,1XT9M@135623|Vibrionales	135623|Vibrionales	JKL	Belongs to the DEAD box helicase family	-	-	-	-	-	-	-	-	-	-	-	-	DEAD,Helicase_C
k141_4141_1	1219065.VPR01S_30_00010	8.53e-111	325.0	COG0543@1|root,COG0543@2|Bacteria,1MV72@1224|Proteobacteria,1RPH5@1236|Gammaproteobacteria,1XVAC@135623|Vibrionales	135623|Vibrionales	C	COG0543 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases	fre	-	1.16.1.3,1.5.1.41	ko:K05368	ko00740,ko00860,ko01100,map00740,map00860,map01100	-	R00097,R05705	RC00126,RC00220	ko00000,ko00001,ko01000	-	-	-	FAD_binding_6,NAD_binding_1
k141_4141_2	273526.SMDB11_4355	7.65e-296	815.0	COG0043@1|root,COG0043@2|Bacteria,1MU62@1224|Proteobacteria,1RNH8@1236|Gammaproteobacteria,40191@613|Serratia	1236|Gammaproteobacteria	H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis	ubiD	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008694,GO:0009058,GO:0009108,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0042180,GO:0042181,GO:0042802,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663	4.1.1.98	ko:K03182	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04985,R04986	RC00391	ko00000,ko00001,ko00002,ko01000	-	-	iECO111_1330.ECO111_4669	UbiD
k141_4141_3	1348635.BBJY01000026_gene2320	2.22e-296	809.0	COG1158@1|root,COG1158@2|Bacteria,1MUCF@1224|Proteobacteria,1RP95@1236|Gammaproteobacteria,1XT0A@135623|Vibrionales	135623|Vibrionales	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
k141_4141_4	1187848.AJYQ01000075_gene1583	6.41e-69	208.0	COG3118@1|root,COG3118@2|Bacteria,1MZBB@1224|Proteobacteria,1S5WR@1236|Gammaproteobacteria,1XXAK@135623|Vibrionales	135623|Vibrionales	O	Belongs to the thioredoxin family	trxA	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
k141_4141_5	243277.VC_0305	1.84e-217	611.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,1RMWA@1236|Gammaproteobacteria,1XTC7@135623|Vibrionales	135623|Vibrionales	JKL	DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA	rhlB	GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009056,GO:0009057,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019439,GO:0034641,GO:0034655,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360,GO:1901361,GO:1901575	3.6.4.13	ko:K03732	ko03018,map03018	M00394	-	-	ko00000,ko00001,ko00002,ko01000,ko03019	-	-	-	DEAD,Helicase_C
k141_4141_6	675806.VII_003424	6.34e-285	787.0	COG0248@1|root,COG0248@2|Bacteria,1MV35@1224|Proteobacteria,1RN3V@1236|Gammaproteobacteria,1XTYW@135623|Vibrionales	135623|Vibrionales	F	Catalyzes the conversion of pppGpp to ppGpp. Guanosine pentaphosphate (pppGpp) is a cytoplasmic signaling molecule which together with ppGpp controls the stringent response , an adaptive process that allows bacteria to respond to amino acid starvation, resulting in the coordinated regulation of numerous cellular activities	gppA	GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006793,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0008894,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0015949,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0034641,GO:0042594,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050896,GO:0051716,GO:0055086,GO:0071496,GO:0071704,GO:1901360	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	Ppx-GppA
k141_4141_7	198628.Dda3937_02956	6.71e-163	471.0	COG5520@1|root,COG5520@2|Bacteria,1R9GV@1224|Proteobacteria,1RZV0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	Belongs to the glycosyl hydrolase 30 family	-	-	-	-	-	-	-	-	-	-	-	-	CBM_2,Glyco_hydro_30,Glyco_hydro_30C
k141_4141_9	345073.VC395_0341	2.14e-85	253.0	COG0757@1|root,COG0757@2|Bacteria,1RDDT@1224|Proteobacteria,1S3PX@1236|Gammaproteobacteria,1XWVA@135623|Vibrionales	135623|Vibrionales	E	Catalyzes a trans-dehydration via an enolate intermediate	aroQ	GO:0003674,GO:0003824,GO:0003855,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576	4.2.1.10	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03084	RC00848	ko00000,ko00001,ko00002,ko01000	-	-	-	DHquinase_II
k141_4141_10	796620.VIBC2010_19645	7e-65	202.0	COG0511@1|root,COG0511@2|Bacteria,1RCXA@1224|Proteobacteria,1S3YP@1236|Gammaproteobacteria,1XWV0@135623|Vibrionales	135623|Vibrionales	I	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA	accB	-	-	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742	RC00040,RC00367	ko00000,ko00001,ko00002	-	-	-	Biotin_lipoyl
k141_4141_11	314292.VAS14_19021	1.97e-311	850.0	COG0439@1|root,COG0439@2|Bacteria,1MU4H@1224|Proteobacteria,1RMNB@1236|Gammaproteobacteria,1XSFE@135623|Vibrionales	135623|Vibrionales	I	Biotin carboxylase	accC	-	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
k141_4141_12	223926.28807909	9.21e-190	529.0	COG2264@1|root,COG2264@2|Bacteria,1MUPC@1224|Proteobacteria,1RNAR@1236|Gammaproteobacteria,1XTMC@135623|Vibrionales	135623|Vibrionales	J	Methylates ribosomal protein L11	prmA	-	-	ko:K02687	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PrmA
k141_4141_13	796620.VIBC2010_19660	1.58e-191	535.0	COG0042@1|root,COG0042@2|Bacteria,1MV5V@1224|Proteobacteria,1RMJP@1236|Gammaproteobacteria,1XV75@135623|Vibrionales	135623|Vibrionales	J	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	dusB	-	-	ko:K05540	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Dus
k141_4141_14	1280001.BAOA01000011_gene4235	6.25e-60	185.0	COG2901@1|root,COG2901@2|Bacteria,1N7MJ@1224|Proteobacteria,1SD35@1236|Gammaproteobacteria,1XXSR@135623|Vibrionales	135623|Vibrionales	K	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters	fis	GO:0000229,GO:0000785,GO:0000786,GO:0000787,GO:0000789,GO:0003674,GO:0003700,GO:0005575,GO:0005622,GO:0005623,GO:0005694,GO:0005737,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0032991,GO:0032993,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044422,GO:0044424,GO:0044427,GO:0044444,GO:0044446,GO:0044464,GO:0044815,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2001141	-	ko:K03557	ko05111,map05111	-	-	-	ko00000,ko00001,ko03000,ko03036,ko03400	-	-	-	HTH_8
k141_4141_15	298386.PBPRA1708	2.3e-35	131.0	COG4469@1|root,COG4469@2|Bacteria,1RFB6@1224|Proteobacteria,1TH8R@1236|Gammaproteobacteria,1XSIK@135623|Vibrionales	135623|Vibrionales	S	Competence protein	-	-	-	-	-	-	-	-	-	-	-	-	CoiA
k141_4141_16	1116375.VEJY3_09440	3.4e-34	119.0	COG3415@1|root,COG3415@2|Bacteria,1RFNA@1224|Proteobacteria,1S5WD@1236|Gammaproteobacteria,1Y2W6@135623|Vibrionales	135623|Vibrionales	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Tnp_1
k141_4534_2	1205908.AKXW01000128_gene442	4.03e-15	71.2	28PFD@1|root,2ZC6I@2|Bacteria,1R8PT@1224|Proteobacteria,1S49D@1236|Gammaproteobacteria,1Y2AI@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_4534_3	1348635.BBJY01000006_gene372	1.22e-52	171.0	28PFD@1|root,2ZC6I@2|Bacteria,1R8PT@1224|Proteobacteria,1S49D@1236|Gammaproteobacteria,1Y2AI@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_4534_4	1517681.HW45_09440	1.33e-136	397.0	COG1609@1|root,COG1609@2|Bacteria,1NZH0@1224|Proteobacteria,1RPMC@1236|Gammaproteobacteria,1Y0AS@135623|Vibrionales	135623|Vibrionales	K	helix_turn _helix lactose operon repressor	-	-	-	-	-	-	-	-	-	-	-	-	LacI,Peripla_BP_3
k141_2104_1	177437.HRM2_09070	1.36e-149	432.0	COG1158@1|root,COG1158@2|Bacteria,1R6YF@1224|Proteobacteria,42P06@68525|delta/epsilon subdivisions,2WK6X@28221|Deltaproteobacteria,2MJEY@213118|Desulfobacterales	28221|Deltaproteobacteria	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	-	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_RNA_bind
k141_2104_2	96561.Dole_0828	4.89e-25	104.0	COG3177@1|root,COG3177@2|Bacteria,1MX0V@1224|Proteobacteria,42NRY@68525|delta/epsilon subdivisions,2WJBD@28221|Deltaproteobacteria,2MHY7@213118|Desulfobacterales	28221|Deltaproteobacteria	S	PFAM filamentation induced by cAMP protein Fic	-	-	-	-	-	-	-	-	-	-	-	-	Fic
k141_4849_2	283699.D172_3277	1.1e-117	364.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RNC3@1236|Gammaproteobacteria,2Q10G@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	T	signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
k141_4849_3	1515746.HR45_08510	3.4e-195	543.0	COG1348@1|root,COG1348@2|Bacteria,1MVTE@1224|Proteobacteria,1RR82@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components the iron protein and the molybdenum-iron protein	nifH	-	1.18.6.1	ko:K02588	ko00625,ko00910,ko01100,ko01120,map00625,map00910,map01100,map01120	M00175	R05185,R05496	RC00002,RC01395,RC02891	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4_NifH
k141_4849_4	1123487.KB892846_gene674	9.05e-19	85.5	COG2710@1|root,COG2710@2|Bacteria,1MVY2@1224|Proteobacteria,2VHMG@28216|Betaproteobacteria,2KVM9@206389|Rhodocyclales	206389|Rhodocyclales	C	Nitrogenase component 1 type Oxidoreductase	-	-	1.18.6.1	ko:K02586	ko00625,ko00910,ko01100,ko01120,map00625,map00910,map01100,map01120	M00175	R05185,R05496	RC00002,RC01395,RC02891	ko00000,ko00001,ko00002,ko01000	-	-	-	Oxidored_nitro
k141_4850_1	1304885.AUEY01000039_gene1545	2.36e-42	150.0	COG0055@1|root,COG0055@2|Bacteria,1MUFU@1224|Proteobacteria,42KZA@68525|delta/epsilon subdivisions,2WJ1V@28221|Deltaproteobacteria,2MI99@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
k141_4850_2	1120956.JHZK01000033_gene178	3.48e-13	68.9	COG0355@1|root,COG0355@2|Bacteria,1RHE4@1224|Proteobacteria,2UBXX@28211|Alphaproteobacteria,1JP7R@119043|Rhodobiaceae	28211|Alphaproteobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpC	GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02113,ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_DE_N
k141_4535_1	1049564.TevJSym_af00930	2.08e-79	264.0	COG1639@1|root,COG2204@1|root,COG1639@2|Bacteria,COG2204@2|Bacteria,1RCW6@1224|Proteobacteria,1S3XV@1236|Gammaproteobacteria,1J6BK@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	T	HDOD domain	-	-	-	-	-	-	-	-	-	-	-	-	HDOD,Response_reg
k141_4142_1	1123236.KB899387_gene1950	1e-17	76.3	2DQKB@1|root,337EE@2|Bacteria,1NC2T@1224|Proteobacteria,1SDTD@1236|Gammaproteobacteria,46C9N@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Protein of unknown function (DUF1656)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1656
k141_4142_2	1515746.HR45_12975	1.34e-115	341.0	COG1566@1|root,COG1566@2|Bacteria,1MWG0@1224|Proteobacteria,1RRE3@1236|Gammaproteobacteria,2QBSE@267890|Shewanellaceae	1236|Gammaproteobacteria	V	Biotin-lipoyl like	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
k141_4142_3	626887.J057_15370	5.23e-26	107.0	COG1289@1|root,COG1289@2|Bacteria,1MX9H@1224|Proteobacteria,1RMJ4@1236|Gammaproteobacteria,4694S@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Fusaric acid resistance protein family	-	-	-	-	-	-	-	-	-	-	-	-	FUSC
k141_4851_1	411902.CLOBOL_00902	7.34e-10	64.7	COG3395@1|root,COG3395@2|Bacteria,1TPNP@1239|Firmicutes,24AJF@186801|Clostridia,21YNX@1506553|Lachnoclostridium	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	2.7.1.219,2.7.1.220	ko:K22129	-	-	-	-	ko00000,ko01000	-	-	-	DUF1357_C,DUF1537
k141_1453_1	1280001.BAOA01000081_gene2986	1.92e-76	241.0	COG0750@1|root,COG0750@2|Bacteria,1MU91@1224|Proteobacteria,1RMIX@1236|Gammaproteobacteria,1XUCN@135623|Vibrionales	135623|Vibrionales	M	Zinc metalloprotease	rseP	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_M50
k141_1453_2	1348635.BBJY01000002_gene3438	1.79e-203	573.0	COG0743@1|root,COG0743@2|Bacteria,1MU4G@1224|Proteobacteria,1RNNW@1236|Gammaproteobacteria,1XT3U@135623|Vibrionales	135623|Vibrionales	I	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)	dxr	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576	1.1.1.267	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05688	RC01452	ko00000,ko00001,ko00002,ko01000	-	-	-	DXPR_C,DXP_redisom_C,DXP_reductoisom
k141_1453_3	55601.VANGNB10_cI2042c	3.66e-124	362.0	COG4589@1|root,COG4589@2|Bacteria,1R34Q@1224|Proteobacteria,1T63B@1236|Gammaproteobacteria,1XSRD@135623|Vibrionales	135623|Vibrionales	S	Belongs to the CDS family	cdsA	-	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
k141_1453_4	243277.VC_2256	8.14e-140	399.0	COG0020@1|root,COG0020@2|Bacteria,1MVP1@1224|Proteobacteria,1RMVX@1236|Gammaproteobacteria,1XTBC@135623|Vibrionales	135623|Vibrionales	H	Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di-trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide	uppS	GO:0000270,GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006022,GO:0006023,GO:0006024,GO:0006066,GO:0006629,GO:0006720,GO:0006807,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
k141_1453_6	1280001.BAOA01000081_gene2981	4.75e-161	452.0	COG0528@1|root,COG0528@2|Bacteria,1MV3N@1224|Proteobacteria,1RMHX@1236|Gammaproteobacteria,1XTPA@135623|Vibrionales	135623|Vibrionales	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	-	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
k141_1453_8	55601.VANGNB10_cI2047c	1.18e-162	456.0	COG0052@1|root,COG0052@2|Bacteria,1MU33@1224|Proteobacteria,1RN0Z@1236|Gammaproteobacteria,1XTTD@135623|Vibrionales	135623|Vibrionales	J	Belongs to the universal ribosomal protein uS2 family	rpsB	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
k141_5244_25	1116375.VEJY3_22326	1.97e-186	526.0	COG0787@1|root,COG0787@2|Bacteria,1MV0Q@1224|Proteobacteria,1RM8U@1236|Gammaproteobacteria,1XSJM@135623|Vibrionales	135623|Vibrionales	M	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	-	-	5.1.1.1	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N
k141_5244_26	207954.MED92_14893	3.44e-220	620.0	COG1115@1|root,COG1115@2|Bacteria,1MUI3@1224|Proteobacteria,1RMNF@1236|Gammaproteobacteria,1XHC5@135619|Oceanospirillales	135619|Oceanospirillales	E	alanine symporter	dagA	-	-	ko:K03310	-	-	-	-	ko00000	2.A.25	-	-	Na_Ala_symp
k141_5244_27	1116375.VEJY3_22331	1.96e-199	557.0	COG3367@1|root,COG3367@2|Bacteria,1MVEX@1224|Proteobacteria,1RNVG@1236|Gammaproteobacteria,1XT33@135623|Vibrionales	135623|Vibrionales	S	Domain of unknown function (DUF1611_N) Rossmann-like domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF1611,DUF1611_N
k141_5244_28	1116375.VEJY3_22336	1.5e-168	478.0	COG4948@1|root,COG4948@2|Bacteria,1MW76@1224|Proteobacteria,1RMKS@1236|Gammaproteobacteria,1XUBP@135623|Vibrionales	135623|Vibrionales	M	Belongs to the mandelate racemase muconate lactonizing enzyme family	-	-	5.1.1.20	ko:K19802	-	-	R10938	RC03309	ko00000,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
k141_3673_1	1219626.HMPREF1639_09010	1.61e-98	296.0	COG1235@1|root,COG1235@2|Bacteria,1TQ8E@1239|Firmicutes,249U2@186801|Clostridia,25QID@186804|Peptostreptococcaceae	186801|Clostridia	S	Metallo-beta-lactamase domain protein	yycJ	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B,Lactamase_B_2
k141_3673_2	1286171.EAL2_c21850	7.82e-217	609.0	COG0766@1|root,COG0766@2|Bacteria,1TPAU@1239|Firmicutes,2488W@186801|Clostridia,25URW@186806|Eubacteriaceae	186801|Clostridia	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
k141_872_2	672.VV93_v1c43970	3.84e-114	385.0	COG2885@1|root,COG2885@2|Bacteria	2|Bacteria	M	chlorophyll binding	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Calx-beta,DUF11,DUF4842,FG-GAP_2,Laminin_G_3,OMP_b-brl,PD40,TSP_3
k141_872_4	126957.SMAR013397-PA	1.52e-06	58.9	COG5640@1|root,KOG4297@1|root,KOG3627@2759|Eukaryota,KOG4297@2759|Eukaryota,38CCF@33154|Opisthokonta,3BP46@33208|Metazoa,3CUGH@33213|Bilateria,41XDR@6656|Arthropoda	33208|Metazoa	O	serine-type endopeptidase activity. It is involved in the biological process described with proteolysis	-	GO:0002376,GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0006508,GO:0006807,GO:0006950,GO:0006952,GO:0006955,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008592,GO:0009605,GO:0009607,GO:0009617,GO:0009966,GO:0010646,GO:0016787,GO:0017171,GO:0019538,GO:0023051,GO:0042742,GO:0043170,GO:0043207,GO:0044238,GO:0045087,GO:0048583,GO:0050789,GO:0050794,GO:0050830,GO:0050896,GO:0051704,GO:0051707,GO:0065007,GO:0070011,GO:0071704,GO:0098542,GO:0140096,GO:1901564	-	ko:K03992,ko:K19904,ko:K20674	ko04610,ko04624,ko05150,map04610,map04624,map05150	-	-	-	ko00000,ko00001,ko01000,ko01002,ko04131	-	-	-	Ldl_recept_a,Sushi,Trypsin
k141_872_5	243277.VC_1198	0.0	1575.0	COG0247@1|root,COG0277@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,1MU6Y@1224|Proteobacteria,1RQX2@1236|Gammaproteobacteria,1XU87@135623|Vibrionales	135623|Vibrionales	C	COG0277 FAD FMN-containing dehydrogenases	ydiJ	-	-	-	-	-	-	-	-	-	-	-	FAD-oxidase_C,FAD_binding_4,Fer4_8
k141_872_6	243277.VC_1197	7.32e-123	355.0	COG1776@1|root,COG1776@2|Bacteria,1N5S9@1224|Proteobacteria,1RMT0@1236|Gammaproteobacteria,1XVBM@135623|Vibrionales	135623|Vibrionales	NT	Protein of unknown function (DUF3334)	SO2241	-	-	-	-	-	-	-	-	-	-	-	DUF3334
k141_3262_1	1123376.AUIU01000012_gene1334	6.19e-53	180.0	COG0196@1|root,COG0196@2|Bacteria,3J0KY@40117|Nitrospirae	40117|Nitrospirae	H	Riboflavin kinase	ribF	-	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
k141_2869_2	879212.DespoDRAFT_01417	1.79e-26	106.0	COG0388@1|root,COG0388@2|Bacteria,1MXG5@1224|Proteobacteria,42PV7@68525|delta/epsilon subdivisions,2WKXE@28221|Deltaproteobacteria,2MJCI@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Carbon-nitrogen hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	CN_hydrolase
k141_4297_1	1347392.CCEZ01000043_gene219	3.9e-42	140.0	2E6IF@1|root,3315M@2|Bacteria,1VAX0@1239|Firmicutes,24N55@186801|Clostridia,36KEX@31979|Clostridiaceae	186801|Clostridia	-	-	ortA	GO:0006082,GO:0006520,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0071704,GO:1901564,GO:1901605	2.3.1.263	ko:K21399	-	-	-	-	ko00000,ko01000	-	-	-	-
k141_4297_2	1121289.JHVL01000005_gene1034	1.23e-241	675.0	COG0031@1|root,COG0031@2|Bacteria,1UI2J@1239|Firmicutes,25EB5@186801|Clostridia,36UJ3@31979|Clostridiaceae	186801|Clostridia	E	Pyridoxal-phosphate dependent enzyme	-	-	2.3.1.263	ko:K21400	-	-	-	-	ko00000,ko01000	-	-	-	PALP
k141_4678_1	1232410.KI421421_gene3588	3.6e-123	370.0	COG1508@1|root,COG1508@2|Bacteria,1MW4V@1224|Proteobacteria,42M3C@68525|delta/epsilon subdivisions,2WJ21@28221|Deltaproteobacteria,43RYZ@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	Sigma-54 factor, Activator interacting domain (AID)	rpoN	-	-	ko:K03092	ko02020,ko05111,map02020,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma54_AID,Sigma54_CBD,Sigma54_DBD
k141_4678_2	1304885.AUEY01000013_gene3089	1.35e-34	122.0	COG1544@1|root,COG1544@2|Bacteria,1MZHW@1224|Proteobacteria,42SJW@68525|delta/epsilon subdivisions,2WPF7@28221|Deltaproteobacteria,2MJVZ@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase	hpf	-	-	ko:K05808	-	-	-	-	ko00000,ko03009	-	-	-	Ribosom_S30AE_C,Ribosomal_S30AE
k141_4678_3	933262.AXAM01000066_gene1680	5.97e-37	129.0	COG1762@1|root,COG1762@2|Bacteria,1RD0E@1224|Proteobacteria,42SD2@68525|delta/epsilon subdivisions,2WP7H@28221|Deltaproteobacteria,2MKBM@213118|Desulfobacterales	28221|Deltaproteobacteria	GT	PFAM phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2	ptsN	-	-	ko:K02806	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	-	-	-	PTS_EIIA_2
k141_3975_1	1232437.KL662015_gene1221	6.16e-83	265.0	COG0144@1|root,COG0781@1|root,COG0144@2|Bacteria,COG0781@2|Bacteria,1MWPE@1224|Proteobacteria,42P2T@68525|delta/epsilon subdivisions,2WJ9B@28221|Deltaproteobacteria,2MI5Y@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA	rsmB	-	2.1.1.176	ko:K03500	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F,Methyltr_RsmF_N,NusB
k141_873_1	545243.BAEV01000189_gene2582	5.49e-90	278.0	COG5433@1|root,COG5433@2|Bacteria,1UZWV@1239|Firmicutes,24DPT@186801|Clostridia,36UF1@31979|Clostridiaceae	186801|Clostridia	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_assoc
k141_1987_1	1173026.Glo7428_4256	7.2e-35	132.0	COG1653@1|root,COG1653@2|Bacteria,1G4XY@1117|Cyanobacteria	1117|Cyanobacteria	G	COG1653 ABC-type sugar transport system, periplasmic component	-	-	-	ko:K10227	ko02010,map02010	M00200	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.5	-	-	SBP_bac_1
k141_1987_2	675813.VIB_002269	1.24e-93	283.0	COG2375@1|root,COG2375@2|Bacteria,1R4TD@1224|Proteobacteria,1RY01@1236|Gammaproteobacteria,1XTJW@135623|Vibrionales	135623|Vibrionales	P	Siderophore-interacting protein	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_9,SIP
k141_1987_3	243277.VC_A0592	2.69e-72	223.0	COG1051@1|root,COG1051@2|Bacteria,1RB8R@1224|Proteobacteria,1S1A6@1236|Gammaproteobacteria,1XSJ6@135623|Vibrionales	135623|Vibrionales	F	COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
k141_4679_1	555079.Toce_1258	3.02e-63	214.0	COG1924@1|root,COG1924@2|Bacteria,1TPU5@1239|Firmicutes,2481F@186801|Clostridia,42FAJ@68295|Thermoanaerobacterales	186801|Clostridia	I	ATPase BadF BadG BcrA BcrD type	hgdC	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG
k141_624_1	1348635.BBJY01000002_gene3394	1.97e-290	802.0	28HIF@1|root,2Z7TX@2|Bacteria,1MY24@1224|Proteobacteria,1RN69@1236|Gammaproteobacteria,1XWMY@135623|Vibrionales	135623|Vibrionales	S	Bacteriophage replication gene A protein (GPA)	-	-	-	-	-	-	-	-	-	-	-	-	Phage_GPA
k141_3676_1	1304885.AUEY01000135_gene2925	7.06e-23	97.8	COG0477@1|root,COG0477@2|Bacteria,1MWUR@1224|Proteobacteria,43BPW@68525|delta/epsilon subdivisions,2X714@28221|Deltaproteobacteria,2MI7Z@213118|Desulfobacterales	28221|Deltaproteobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
k141_3676_2	879212.DespoDRAFT_03304	9.44e-89	276.0	COG1236@1|root,COG1236@2|Bacteria,1MUDD@1224|Proteobacteria,42N91@68525|delta/epsilon subdivisions,2WIMM@28221|Deltaproteobacteria,2MJ3X@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Beta-Casp domain	-	-	-	ko:K07576	-	-	-	-	ko00000	-	-	-	Beta-Casp,Lactamase_B,RMMBL
k141_4967_2	1121324.CLIT_14c00020	4.97e-57	181.0	COG4492@1|root,COG4492@2|Bacteria,1VAJ9@1239|Firmicutes,24MTS@186801|Clostridia,25TTI@186804|Peptostreptococcaceae	186801|Clostridia	S	Belongs to the UPF0735 family	pheB	-	5.4.99.5	ko:K06209	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R01715	RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,ACT_4
k141_4967_3	1415775.U729_1846	1.63e-57	194.0	COG0083@1|root,COG0083@2|Bacteria,1TRWS@1239|Firmicutes,248NA@186801|Clostridia,36FBC@31979|Clostridiaceae	186801|Clostridia	F	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate	thrB	-	2.7.1.39	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	M00018	R01771	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS03525	GHMP_kinases_C,GHMP_kinases_N
k141_4967_4	1511.CLOST_2394	1.85e-140	409.0	COG0498@1|root,COG0498@2|Bacteria,1TP25@1239|Firmicutes,25B08@186801|Clostridia,25QDJ@186804|Peptostreptococcaceae	186801|Clostridia	E	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine	thrC	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
k141_4967_5	394503.Ccel_3460	3.97e-177	522.0	COG1164@1|root,COG1164@2|Bacteria,1TP4P@1239|Firmicutes,248TP@186801|Clostridia,36DG9@31979|Clostridiaceae	186801|Clostridia	E	oligoendopeptidase F	pepF	-	-	ko:K08602	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3,Peptidase_M3_N
k141_4967_6	1121324.CLIT_23c02190	5.76e-226	632.0	COG1775@1|root,COG1775@2|Bacteria,1TPEF@1239|Firmicutes,24A11@186801|Clostridia,25QCD@186804|Peptostreptococcaceae	186801|Clostridia	E	2-hydroxyglutaryl-CoA dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	HGD-D
k141_4967_7	1540257.JQMW01000011_gene2191	7.06e-14	67.8	2DR4V@1|root,33A63@2|Bacteria,1VKGM@1239|Firmicutes,24SDY@186801|Clostridia,36MWE@31979|Clostridiaceae	186801|Clostridia	S	Protein of unknown function (DUF3343)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3343
k141_4967_8	273068.TTE1113	1.59e-65	219.0	COG1775@1|root,COG1924@1|root,COG1775@2|Bacteria,COG1924@2|Bacteria,1TQSD@1239|Firmicutes,2481W@186801|Clostridia,42F39@68295|Thermoanaerobacterales	186801|Clostridia	I	PFAM ATPase, BadF BadG BcrA BcrD type	hgdC_1	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG,HGD-D
k141_4967_9	864565.HMPREF0379_0916	5.9e-121	365.0	COG3434@1|root,COG3434@2|Bacteria,1TPWC@1239|Firmicutes,248M1@186801|Clostridia,25TG5@186804|Peptostreptococcaceae	186801|Clostridia	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,HDOD
k141_4967_10	635013.TherJR_2416	1.05e-103	315.0	COG2008@1|root,COG2008@2|Bacteria,1TPZI@1239|Firmicutes,248TR@186801|Clostridia,2621Y@186807|Peptococcaceae	186801|Clostridia	E	PFAM Beta-eliminating lyase	ltaE	-	4.1.2.48	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	-	R00751,R06171	RC00312,RC00372	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
k141_4967_11	1304284.L21TH_1589	3.37e-197	561.0	COG1115@1|root,COG1115@2|Bacteria,1TNZP@1239|Firmicutes,247S6@186801|Clostridia,36F13@31979|Clostridiaceae	186801|Clostridia	E	amino acid carrier protein	agcS	-	-	ko:K03310	-	-	-	-	ko00000	2.A.25	-	-	Na_Ala_symp
k141_4967_12	1121324.CLIT_5c00530	1.74e-93	281.0	COG2859@1|root,COG2859@2|Bacteria,1V1Q4@1239|Firmicutes,24GEE@186801|Clostridia	186801|Clostridia	L	Protein of unknown function (DUF541)	-	-	-	ko:K09797	-	-	-	-	ko00000	-	-	-	SIMPL
k141_4967_15	1123009.AUID01000029_gene430	6.29e-188	529.0	COG3177@1|root,COG3177@2|Bacteria,1TQMC@1239|Firmicutes,248JU@186801|Clostridia,26A60@186813|unclassified Clostridiales	186801|Clostridia	S	Fic/DOC family	-	-	-	-	-	-	-	-	-	-	-	-	Fic
k141_4967_16	1499689.CCNN01000014_gene3235	1.34e-64	214.0	2A2TX@1|root,30R7T@2|Bacteria,1VC6M@1239|Firmicutes,24EGB@186801|Clostridia,36H2H@31979|Clostridiaceae	186801|Clostridia	S	Protein of unknown function (DUF3829)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3829
k141_4967_19	335541.Swol_1096	1.46e-144	432.0	COG4124@1|root,COG4124@2|Bacteria,1U8S3@1239|Firmicutes,24C93@186801|Clostridia	186801|Clostridia	G	Glycosyl hydrolase family 26	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_26
k141_4967_20	293826.Amet_3704	4.15e-108	335.0	COG1757@1|root,COG1757@2|Bacteria,1TQ3B@1239|Firmicutes,248WN@186801|Clostridia,36FFK@31979|Clostridiaceae	186801|Clostridia	C	Na H antiporter	nhaC	-	-	ko:K03315	-	-	-	-	ko00000,ko02000	2.A.35	-	-	Na_H_antiporter
k141_4967_21	865861.AZSU01000006_gene1368	2.96e-54	175.0	29CHX@1|root,2ZZGD@2|Bacteria,1V7PD@1239|Firmicutes,24HKB@186801|Clostridia,36IP9@31979|Clostridiaceae	186801|Clostridia	S	HutP	hutP	-	-	-	-	-	-	-	-	-	-	-	HutP
k141_4967_22	1121289.JHVL01000028_gene509	2.41e-147	425.0	COG0701@1|root,COG0701@2|Bacteria,1TQC7@1239|Firmicutes,24A02@186801|Clostridia,36EPA@31979|Clostridiaceae	186801|Clostridia	S	permease	-	-	-	ko:K07089	-	-	-	-	ko00000	-	-	-	ArsP_1
k141_4967_23	521460.Athe_2641	4.9e-27	100.0	COG0526@1|root,COG0526@2|Bacteria,1VEYC@1239|Firmicutes,24QMF@186801|Clostridia,42H6Q@68295|Thermoanaerobacterales	186801|Clostridia	CO	redox-active disulfide protein 2	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_3
k141_4967_24	1487921.DP68_12495	9.12e-35	130.0	2AYHW@1|root,31QMC@2|Bacteria,1V6S7@1239|Firmicutes,24NBV@186801|Clostridia,36JKA@31979|Clostridiaceae	186801|Clostridia	S	TraX protein	-	-	-	-	-	-	-	-	-	-	-	-	TraX
k141_4967_26	12336.Q332K6_CBCP	2.95e-72	219.0	4QH1U@10239|Viruses,4QW4R@35237|dsDNA viruses  no RNA stage,4QPQW@28883|Caudovirales,4QJ32@10662|Myoviridae	10662|Myoviridae	S	Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_4967_27	1410674.JNKU01000042_gene2164	1.02e-209	597.0	COG0675@1|root,COG0675@2|Bacteria,1TQKT@1239|Firmicutes,4HDNU@91061|Bacilli,3FA7E@33958|Lactobacillaceae	91061|Bacilli	L	Transposase, IS605 OrfB family	-	-	-	-	-	-	-	-	-	-	-	-	OrfB_IS605
k141_4967_29	865861.AZSU01000006_gene1369	2.96e-113	338.0	COG2984@1|root,COG2984@2|Bacteria,1TPB0@1239|Firmicutes,248X3@186801|Clostridia,36EB5@31979|Clostridiaceae	186801|Clostridia	S	ABC transporter	-	-	-	ko:K01989	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_sub_bind
k141_4967_30	1347392.CCEZ01000019_gene1060	1.89e-96	292.0	COG4120@1|root,COG4120@2|Bacteria,1TPDJ@1239|Firmicutes,249P1@186801|Clostridia,36EMV@31979|Clostridiaceae	186801|Clostridia	S	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K05832	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	BPD_transp_2
k141_4967_31	596323.HMPREF0554_0235	3.35e-80	249.0	COG1101@1|root,COG1101@2|Bacteria,378KE@32066|Fusobacteria	32066|Fusobacteria	S	ABC transporter	-	-	-	ko:K05833	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_tran
k141_4967_34	1469948.JPNB01000001_gene710	1.85e-25	99.8	COG3422@1|root,COG3422@2|Bacteria,1VDBT@1239|Firmicutes,24PRF@186801|Clostridia	186801|Clostridia	S	Domain of unknown function (DUF1508)	-	-	-	ko:K09946	-	-	-	-	ko00000	-	-	-	DUF1508
k141_4967_36	1151292.QEW_3400	2.19e-81	270.0	COG0728@1|root,COG0728@2|Bacteria,1TPFI@1239|Firmicutes,247N3@186801|Clostridia,25R0J@186804|Peptostreptococcaceae	186801|Clostridia	S	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane	murJ	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
k141_4967_37	1211817.CCAT010000043_gene3484	2.06e-234	659.0	COG1757@1|root,COG1757@2|Bacteria,1TQPI@1239|Firmicutes,25MHZ@186801|Clostridia,36F0F@31979|Clostridiaceae	186801|Clostridia	C	Na+/H+ antiporter family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_antiporter
k141_4967_40	935837.JAEK01000007_gene3282	6.38e-177	513.0	COG0659@1|root,COG0659@2|Bacteria,1TPI4@1239|Firmicutes,4H9V4@91061|Bacilli,1ZCKC@1386|Bacillus	91061|Bacilli	P	COG0659 Sulfate permease and related transporters (MFS superfamily)	ybaR	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
k141_4967_42	272563.CD630_27790	1.41e-155	448.0	COG0836@1|root,COG0836@2|Bacteria,1TPC9@1239|Firmicutes,24908@186801|Clostridia,25T1R@186804|Peptostreptococcaceae	186801|Clostridia	M	Mannose-6-phosphate isomerase	manC	-	2.7.7.13	ko:K00971	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	M00114,M00361,M00362	R00885	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	MannoseP_isomer,NTP_transferase
k141_4967_43	1408823.AXUS01000011_gene2023	4.62e-46	167.0	COG1609@1|root,COG1609@2|Bacteria,1TQ7K@1239|Firmicutes,247M2@186801|Clostridia,25SIR@186804|Peptostreptococcaceae	186801|Clostridia	K	helix_turn _helix lactose operon repressor	rbsR	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_1,Peripla_BP_3
k141_4967_44	1121324.CLIT_12c00220	1.24e-63	204.0	2BDGA@1|root,3275F@2|Bacteria,1UT1B@1239|Firmicutes,250U0@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_4967_45	1121324.CLIT_12c00230	0.0	1229.0	COG0653@1|root,COG0653@2|Bacteria,1TPEY@1239|Firmicutes,247N2@186801|Clostridia,25R40@186804|Peptostreptococcaceae	186801|Clostridia	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	-	-	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	SecA_DEAD,SecA_PP_bind,SecA_SW
k141_4967_46	29176.XP_003884624.1	4.86e-22	110.0	COG1404@1|root,KOG1153@2759|Eukaryota,3YFEN@5794|Apicomplexa,3YIEN@5796|Coccidia,3YSCI@5809|Sarcocystidae	5794|Apicomplexa	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
k141_3694_10	1348635.BBJY01000007_gene151	3.47e-107	330.0	COG5301@1|root,COG5301@2|Bacteria	2|Bacteria	G	cellulose 1,4-beta-cellobiosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF3751
k141_3694_11	1348635.BBJY01000007_gene152	3.9e-133	379.0	COG4385@1|root,COG4385@2|Bacteria,1NZST@1224|Proteobacteria,1RQRK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	tail protein	I	-	-	-	-	-	-	-	-	-	-	-	Tail_P2_I
k141_3694_12	1348635.BBJY01000007_gene153	8.6e-176	493.0	COG3948@1|root,COG3948@2|Bacteria,1MUFF@1224|Proteobacteria,1RNBJ@1236|Gammaproteobacteria,1XYVV@135623|Vibrionales	135623|Vibrionales	S	Baseplate J-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Baseplate_J
k141_3694_13	1348635.BBJY01000007_gene154	5.27e-60	186.0	2AXHC@1|root,31PH1@2|Bacteria,1QM6S@1224|Proteobacteria,1TJER@1236|Gammaproteobacteria,1Y14I@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_2321_1	1348635.BBJY01000001_gene2379	6.4e-217	615.0	COG4656@1|root,COG4656@2|Bacteria,1QTUI@1224|Proteobacteria,1RMIM@1236|Gammaproteobacteria,1XZTE@135623|Vibrionales	135623|Vibrionales	C	RnfC Barrel sandwich hybrid domain	-	-	-	ko:K03615	-	-	-	-	ko00000	-	-	-	Complex1_51K,RnfC_N,SLBB
k141_2321_2	1348635.BBJY01000001_gene2380	6.66e-80	242.0	COG2878@1|root,COG2878@2|Bacteria,1RE44@1224|Proteobacteria,1S5MU@1236|Gammaproteobacteria,1Y0KD@135623|Vibrionales	135623|Vibrionales	C	Putative Fe-S cluster	-	-	-	ko:K03616	-	-	-	-	ko00000	-	-	-	FeS,Fer4_21
k141_2321_3	1116375.VEJY3_18876	2.4e-56	180.0	COG4657@1|root,COG4657@2|Bacteria,1MU8X@1224|Proteobacteria,1RZY6@1236|Gammaproteobacteria,1XZTK@135623|Vibrionales	135623|Vibrionales	C	Rnf-Nqr subunit, membrane protein	-	-	-	ko:K03617	-	-	-	-	ko00000	-	-	-	Rnf-Nqr
k141_2893_2	1304885.AUEY01000022_gene3399	0.0	886.0	COG1304@1|root,COG1304@2|Bacteria,1P72V@1224|Proteobacteria,42NSD@68525|delta/epsilon subdivisions,2WJRW@28221|Deltaproteobacteria,2MHNN@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Conserved region in glutamate synthase	-	-	-	-	-	-	-	-	-	-	-	-	Glu_synthase
k141_3695_1	1158318.ATXC01000001_gene1005	1.77e-41	140.0	COG2050@1|root,COG2050@2|Bacteria,2G45Y@200783|Aquificae	200783|Aquificae	Q	PFAM thioesterase superfamily protein	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
k141_3695_2	324602.Caur_2824	1.78e-10	62.4	COG0642@1|root,COG2203@1|root,COG2203@2|Bacteria,COG2205@2|Bacteria,2GABQ@200795|Chloroflexi,3751C@32061|Chloroflexia	32061|Chloroflexia	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF3369,GAF,GAF_2,HATPase_c,HisKA,PAS_4
k141_4718_1	243277.VC_A0699	1.42e-106	318.0	COG0448@1|root,COG0448@2|Bacteria,1MVTC@1224|Proteobacteria,1RP04@1236|Gammaproteobacteria,1XTGB@135623|Vibrionales	135623|Vibrionales	H	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans	glgC2	GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0008878,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016772,GO:0016779,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0055114,GO:0070566,GO:0071704,GO:1901576	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
k141_4718_2	1121918.ARWE01000001_gene3240	2.48e-10	61.6	COG0715@1|root,COG4191@1|root,COG0715@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,43CE0@68525|delta/epsilon subdivisions	1224|Proteobacteria	T	Bacterial periplasmic substrate-binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,NMT1,PAS_3,PAS_4,PAS_9,Response_reg,SBP_bac_3
k141_2575_1	96561.Dole_1658	1.08e-47	161.0	COG1596@1|root,COG1596@2|Bacteria,1N7GP@1224|Proteobacteria,42MNP@68525|delta/epsilon subdivisions,2WMJZ@28221|Deltaproteobacteria,2MJAM@213118|Desulfobacterales	28221|Deltaproteobacteria	M	export protein	wza2	-	-	ko:K01991	ko02026,map02026	-	-	-	ko00000,ko00001,ko02000	1.B.18	-	-	Poly_export,SLBB
k141_4097_1	338963.Pcar_2335	1.46e-16	78.6	COG0217@1|root,COG0217@2|Bacteria,1MW3X@1224|Proteobacteria,42N7Q@68525|delta/epsilon subdivisions,2WJ1I@28221|Deltaproteobacteria,43S0S@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	Transcriptional regulator	yebC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
k141_4097_2	502025.Hoch_6456	1.27e-47	187.0	COG1404@1|root,COG1404@2|Bacteria,1MU3S@1224|Proteobacteria,42Q14@68525|delta/epsilon subdivisions,2WJ8C@28221|Deltaproteobacteria,2YX9F@29|Myxococcales	28221|Deltaproteobacteria	O	Belongs to the peptidase S8 family	-	-	-	ko:K14645	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	Peptidase_S8
k141_3086_1	1280001.BAOA01000038_gene4407	1.6e-231	640.0	COG2933@1|root,COG2933@2|Bacteria,1MWBM@1224|Proteobacteria,1RMSB@1236|Gammaproteobacteria,1XV45@135623|Vibrionales	135623|Vibrionales	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily	rlmM	-	2.1.1.186	ko:K06968	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ
k141_3086_2	675814.VIC_001908	2.47e-41	140.0	COG2363@1|root,COG2363@2|Bacteria,1MZX3@1224|Proteobacteria,1SCNB@1236|Gammaproteobacteria,1XXBJ@135623|Vibrionales	135623|Vibrionales	S	small membrane protein	ygdD	-	-	-	-	-	-	-	-	-	-	-	DUF423
k141_3086_4	29495.EA26_04240	1.59e-117	349.0	COG0301@1|root,COG0607@1|root,COG0301@2|Bacteria,COG0607@2|Bacteria,1MWD3@1224|Proteobacteria,1RNZT@1236|Gammaproteobacteria,1XT1D@135623|Vibrionales	135623|Vibrionales	H	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS	thiI	GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.8.1.4	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07461	-	ko00000,ko00001,ko01000,ko03016	-	-	-	THUMP,ThiI
k141_1377_1	1216932.CM240_0085	7.69e-174	496.0	COG0675@1|root,COG0675@2|Bacteria,1TRNY@1239|Firmicutes,247T1@186801|Clostridia,36E4A@31979|Clostridiaceae	186801|Clostridia	L	Transposase	-	-	-	ko:K07496	-	-	-	-	ko00000	-	-	-	HTH_OrfB_IS605,OrfB_IS605,OrfB_Zn_ribbon
k141_32_1	665571.STHERM_c19190	7.57e-118	390.0	COG5001@1|root,COG5002@1|root,COG5001@2|Bacteria,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	EAL,GAF,GGDEF,HAMP,HATPase_c,HisKA_2,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg,SpoIIE
k141_1724_1	123214.PERMA_1251	1.71e-75	243.0	COG0405@1|root,COG0405@2|Bacteria,2G3M5@200783|Aquificae	2|Bacteria	E	Gamma-glutamyltranspeptidase	-	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
k141_1724_2	456442.Mboo_0639	4.91e-38	140.0	COG3741@1|root,arCOG08266@2157|Archaea	2157|Archaea	E	N-formylglutamate amidohydrolase	-	-	3.5.3.8	ko:K01479	ko00340,ko01100,map00340,map01100	M00045	R02285	RC00221,RC00681	ko00000,ko00001,ko00002,ko01000	-	-	-	FGase
k141_2726_1	945543.VIBR0546_03670	1.07e-107	316.0	COG2030@1|root,COG2030@2|Bacteria,1RAHS@1224|Proteobacteria,1T0EH@1236|Gammaproteobacteria,1XTU1@135623|Vibrionales	135623|Vibrionales	I	COG2030 Acyl dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
k141_697_1	318167.Sfri_1374	2.49e-93	281.0	COG0451@1|root,COG0451@2|Bacteria,1MU7J@1224|Proteobacteria,1RPTA@1236|Gammaproteobacteria,2Q8KK@267890|Shewanellaceae	1236|Gammaproteobacteria	M	PFAM NAD-dependent epimerase dehydratase	lspL	-	5.1.3.25,5.1.3.6	ko:K08679,ko:K17947	ko00520,ko00523,ko01100,ko01130,map00520,map00523,map01100,map01130	-	R01385,R10279	RC00289	ko00000,ko00001,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
k141_697_2	1051646.VITU9109_23500	5.19e-172	493.0	28I6N@1|root,2Z89J@2|Bacteria,1MUVT@1224|Proteobacteria,1RQUY@1236|Gammaproteobacteria,1XSSM@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_697_3	1187848.AJYQ01000153_gene3267	1.92e-119	349.0	COG2834@1|root,COG2834@2|Bacteria,1MXW0@1224|Proteobacteria,1RS0K@1236|Gammaproteobacteria,1XVD7@135623|Vibrionales	135623|Vibrionales	M	Outer membrane lipoprotein-sorting protein	-	-	-	-	-	-	-	-	-	-	-	-	LolA_like
k141_697_4	1238450.VIBNISOn1_1160006	0.0	917.0	COG1033@1|root,COG1033@2|Bacteria,1MUE1@1224|Proteobacteria,1RPIP@1236|Gammaproteobacteria,1XUBX@135623|Vibrionales	135623|Vibrionales	S	of the RND superfamily	VP1286	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
k141_697_5	1120970.AUBZ01000003_gene162	6.98e-173	495.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria,4650W@72275|Alteromonadaceae	1236|Gammaproteobacteria	T	COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains	prsR	-	-	ko:K02481	-	-	-	-	ko00000,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
k141_2727_1	96561.Dole_2113	5.61e-117	348.0	COG0034@1|root,COG0034@2|Bacteria,1R7JX@1224|Proteobacteria,42MAC@68525|delta/epsilon subdivisions,2WKFD@28221|Deltaproteobacteria,2MIUW@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Glutamine amidotransferase domain	-	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_7
k141_34_1	1121324.CLIT_10c01450	8.9e-20	87.4	COG0370@1|root,COG0370@2|Bacteria,1TP7E@1239|Firmicutes,24885@186801|Clostridia,25R2H@186804|Peptostreptococcaceae	186801|Clostridia	P	transporter of a GTP-driven Fe(2 ) uptake system	feoB	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoB_C,FeoB_N,Gate
k141_34_2	1511.CLOST_1060	2.44e-25	97.8	COG1918@1|root,COG1918@2|Bacteria,1VCU6@1239|Firmicutes,25D5T@186801|Clostridia	186801|Clostridia	P	FeoA	-	-	-	ko:K04758	-	-	-	-	ko00000,ko02000	-	-	-	FeoA
k141_1727_1	29495.EA26_16080	1.34e-258	718.0	COG0469@1|root,COG0469@2|Bacteria,1MU21@1224|Proteobacteria,1RMW3@1236|Gammaproteobacteria,1XSQD@135623|Vibrionales	135623|Vibrionales	G	Belongs to the pyruvate kinase family	pykA	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PK,PK_C
k141_698_2	1051646.VITU9109_16718	6.41e-101	300.0	COG0561@1|root,COG0561@2|Bacteria,1Q5HK@1224|Proteobacteria,1RQ8H@1236|Gammaproteobacteria,1XTJJ@135623|Vibrionales	135623|Vibrionales	S	hydrolases of the HAD superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
k141_3758_1	1224318.DT73_01185	0.0	977.0	COG0028@1|root,COG0028@2|Bacteria,1MWKP@1224|Proteobacteria,1RNYT@1236|Gammaproteobacteria	1236|Gammaproteobacteria	EH	Belongs to the TPP enzyme family	poxB	GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006090,GO:0008150,GO:0008152,GO:0008289,GO:0009056,GO:0009987,GO:0016020,GO:0016043,GO:0016054,GO:0016491,GO:0016903,GO:0019752,GO:0019842,GO:0022607,GO:0030976,GO:0032787,GO:0036094,GO:0042802,GO:0042867,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0046872,GO:0048037,GO:0050660,GO:0050662,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0052737,GO:0052738,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0071944,GO:0072329,GO:0097159,GO:1901265,GO:1901363,GO:1901575,GO:1901681	1.2.3.3,1.2.5.1	ko:K00156,ko:K00158	ko00620,ko01100,map00620,map01100	-	R00207,R03145	RC00860,RC02745	ko00000,ko00001,ko01000	-	-	iSF_1195.SF0826,iSFxv_1172.SFxv_0895,iS_1188.S0867	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
k141_3758_2	945543.VIBR0546_01183	5.99e-71	213.0	COG3060@1|root,COG3060@2|Bacteria,1RH3B@1224|Proteobacteria,1S5ZV@1236|Gammaproteobacteria,1XX9T@135623|Vibrionales	135623|Vibrionales	K	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis	metJ	GO:0000096,GO:0003674,GO:0003700,GO:0006082,GO:0006355,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0019752,GO:0031323,GO:0031326,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0140110,GO:1901564,GO:1901605,GO:1903506,GO:2000112,GO:2001141	-	ko:K03764	-	-	-	-	ko00000,ko03000	-	-	-	MetJ
k141_3758_3	1517681.HW45_27145	1.71e-218	610.0	COG0626@1|root,COG0626@2|Bacteria,1MU57@1224|Proteobacteria,1RMCV@1236|Gammaproteobacteria,1XSFT@135623|Vibrionales	135623|Vibrionales	E	COG0626 Cystathionine beta-lyases cystathionine gamma-synthases	metB	-	2.5.1.48	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017	R00999,R01288,R02508,R03217,R03260,R04944,R04945,R04946	RC00020,RC00056,RC00069,RC00420,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000	-	-	-	Cys_Met_Meta_PP
k141_3758_4	223926.28807774	1.94e-203	589.0	COG0460@1|root,COG0527@1|root,COG0460@2|Bacteria,COG0527@2|Bacteria,1MW3H@1224|Proteobacteria,1RN1G@1236|Gammaproteobacteria,1XSVP@135623|Vibrionales	135623|Vibrionales	E	Bifunctional aspartate kinase II homoserine dehydrogenase II	metL	-	1.1.1.3,2.7.2.4	ko:K12525	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00017,M00018,M00526,M00527	R00480,R01773,R01775	RC00002,RC00043,RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,Homoserine_dh,NAD_binding_3
k141_3405_1	318464.IO99_14870	1.26e-23	114.0	COG2199@1|root,COG3899@1|root,COG3706@2|Bacteria,COG3899@2|Bacteria,1V9Y7@1239|Firmicutes,24A8B@186801|Clostridia,36E8P@31979|Clostridiaceae	186801|Clostridia	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GGDEF,Pkinase,TPR_12,TPR_8
k141_3405_2	350688.Clos_1842	2.75e-46	155.0	COG3366@1|root,COG3366@2|Bacteria,1UHXB@1239|Firmicutes,24PK4@186801|Clostridia,36UUG@31979|Clostridiaceae	186801|Clostridia	S	PFAM nucleoside recognition domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Gate
k141_3405_3	1408422.JHYF01000013_gene481	8.28e-46	152.0	COG0370@1|root,COG0370@2|Bacteria,1TQT3@1239|Firmicutes,24MTG@186801|Clostridia,36MDA@31979|Clostridiaceae	186801|Clostridia	P	Nucleoside recognition	-	-	-	-	-	-	-	-	-	-	-	-	Gate
k141_3405_4	941824.TCEL_02243	1.56e-105	315.0	COG0190@1|root,COG0190@2|Bacteria,1TP1P@1239|Firmicutes,248DB@186801|Clostridia,36FBW@31979|Clostridiaceae	186801|Clostridia	F	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	-	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
k141_3405_5	446470.Snas_5039	3.2e-16	81.3	COG3404@1|root,COG3404@2|Bacteria,2IIRF@201174|Actinobacteria,4EYGJ@85014|Glycomycetales	201174|Actinobacteria	E	Formiminotransferase-cyclodeaminase	-	-	-	-	-	-	-	-	-	-	-	-	FTCD_C
k141_3405_6	1391646.AVSU01000056_gene1308	6.13e-294	815.0	COG2759@1|root,COG2759@2|Bacteria,1TP6N@1239|Firmicutes,247P5@186801|Clostridia,25QRD@186804|Peptostreptococcaceae	186801|Clostridia	H	Formyltetrahydrofolate synthetase	fhs	-	6.3.4.3	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R00943	RC00026,RC00111	ko00000,ko00001,ko00002,ko01000	-	-	-	FTHFS
k141_3405_7	1031288.AXAA01000003_gene1616	1.92e-79	241.0	COG1838@1|root,COG1838@2|Bacteria,1V1CP@1239|Firmicutes,24FRK@186801|Clostridia,36EM4@31979|Clostridiaceae	186801|Clostridia	C	Fe-S type, tartrate fumarate subfamily, beta	fumB	-	4.2.1.2	ko:K01678	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumerase_C
k141_3405_8	1209989.TepiRe1_0545	7.33e-129	374.0	COG1951@1|root,COG1951@2|Bacteria,1TPXQ@1239|Firmicutes,248T7@186801|Clostridia,42EX5@68295|Thermoanaerobacterales	186801|Clostridia	C	hydro-lyase, Fe-S type, tartrate fumarate subfamily, alpha subunit	-	-	4.2.1.2	ko:K01677	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumerase
k141_3405_9	1301100.HG529407_gene252	1.25e-130	380.0	COG0280@1|root,COG0280@2|Bacteria,1TRQU@1239|Firmicutes,24857@186801|Clostridia,36DC6@31979|Clostridiaceae	186801|Clostridia	C	phosphate butyryltransferase	ptb1	-	2.3.1.19	ko:K00634	ko00650,ko01100,map00650,map01100	-	R01174	RC00004,RC02816	ko00000,ko00001,ko01000	-	-	-	PTA_PTB
k141_3405_12	1499689.CCNN01000013_gene3079	3.96e-150	442.0	COG0617@1|root,COG0617@2|Bacteria,1TQ2A@1239|Firmicutes,247XC@186801|Clostridia,36FRJ@31979|Clostridiaceae	186801|Clostridia	J	tRNA nucleotidyltransferase poly(A) polymerase	cca	-	2.7.7.19,2.7.7.72	ko:K00970,ko:K00974	ko03013,ko03018,map03013,map03018	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	HD,PolyA_pol,PolyA_pol_RNAbd,tRNA_NucTran2_2
k141_3405_13	1292035.H476_0634	5.46e-227	637.0	COG1757@1|root,COG1757@2|Bacteria,1TQPI@1239|Firmicutes,2495U@186801|Clostridia,25QPI@186804|Peptostreptococcaceae	186801|Clostridia	C	Na+/H+ antiporter family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_antiporter
k141_3405_14	445972.ANACOL_02791	5.5e-10	55.8	COG1773@1|root,COG1773@2|Bacteria,1VEQC@1239|Firmicutes,24QUV@186801|Clostridia,3WKG3@541000|Ruminococcaceae	186801|Clostridia	C	PFAM Rubredoxin-type Fe(Cys)4 protein	rub	-	1.18.1.1	ko:K05297	ko00071,map00071	-	R02000	-	ko00000,ko00001,ko01000	-	-	-	Rubredoxin
k141_3405_15	1511.CLOST_1096	3.35e-92	274.0	COG4189@1|root,COG4189@2|Bacteria,1UHX2@1239|Firmicutes,25E60@186801|Clostridia,25UNM@186804|Peptostreptococcaceae	186801|Clostridia	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
k141_3405_16	1121324.CLIT_10c02880	6.84e-211	603.0	COG0572@1|root,COG0572@2|Bacteria,1TQ4V@1239|Firmicutes,249IT@186801|Clostridia,25QMT@186804|Peptostreptococcaceae	186801|Clostridia	FJ	Phosphoribulokinase / Uridine kinase family	udk	-	2.7.1.48	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R00513,R00516,R00517,R00962,R00964,R00967,R00968,R00970,R01548,R01549,R01880,R02091,R02096,R02097,R02327,R02332,R02371,R02372,R08232	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PRK
k141_3405_17	1121324.CLIT_10c02890	3.08e-26	109.0	COG0648@1|root,COG0648@2|Bacteria,1UFG6@1239|Firmicutes,24FBC@186801|Clostridia,25RBT@186804|Peptostreptococcaceae	186801|Clostridia	L	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
k141_3405_18	1121324.CLIT_10c02900	6.57e-76	232.0	COG0681@1|root,COG0681@2|Bacteria,1V7H9@1239|Firmicutes,24MVR@186801|Clostridia,25TG3@186804|Peptostreptococcaceae	186801|Clostridia	U	Signal peptidase, peptidase S26	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24
k141_3405_19	1121324.CLIT_10c02910	4.8e-93	282.0	arCOG00127@1|root,33TE0@2|Bacteria,1VQPB@1239|Firmicutes,24ZZX@186801|Clostridia	186801|Clostridia	C	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_3405_20	138119.DSY0745	0.000136	48.1	COG1559@1|root,COG1559@2|Bacteria,1VZ75@1239|Firmicutes,24UQ1@186801|Clostridia,2662J@186807|Peptococcaceae	186801|Clostridia	S	periplasmic solute-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	YceG
k141_3405_21	203120.LEUM_1797	3.04e-55	184.0	COG2071@1|root,COG2071@2|Bacteria,1V1KC@1239|Firmicutes,4HI59@91061|Bacilli,4AX0S@81850|Leuconostocaceae	91061|Bacilli	S	Peptidase C26	puuD	-	-	ko:K07010	-	-	-	-	ko00000,ko01002	-	-	-	Peptidase_C26
k141_3405_22	931626.Awo_c17560	1.07e-129	383.0	COG3437@1|root,COG3437@2|Bacteria,1UQJH@1239|Firmicutes,248UM@186801|Clostridia,25V1R@186806|Eubacteriaceae	186801|Clostridia	T	Psort location Cytoplasmic, score	-	-	-	ko:K07814	-	-	-	-	ko00000,ko02022	-	-	-	HD,HD_5,PAS_3,Response_reg
k141_3405_23	1121405.dsmv_2602	2.39e-143	488.0	COG0642@1|root,COG0715@1|root,COG5002@1|root,COG0642@2|Bacteria,COG0715@2|Bacteria,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,42NK9@68525|delta/epsilon subdivisions,2X7E0@28221|Deltaproteobacteria,2MITZ@213118|Desulfobacterales	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,PAS,PAS_4,PAS_9,Response_reg,SBP_bac_3
k141_3405_24	42256.RradSPS_0680	4.54e-07	54.7	COG0517@1|root,COG0517@2|Bacteria,2HPZ3@201174|Actinobacteria,4CREF@84995|Rubrobacteria	84995|Rubrobacteria	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
k141_3405_27	1408423.JHYA01000007_gene175	3.58e-33	144.0	COG0840@1|root,COG0840@2|Bacteria,1TP5A@1239|Firmicutes,4H3BE@909932|Negativicutes	909932|Negativicutes	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal,dCache_1
k141_3405_28	1232452.BAIB02000006_gene1020	2.75e-68	225.0	COG0482@1|root,COG0482@2|Bacteria,1TPIZ@1239|Firmicutes,247YV@186801|Clostridia,2687M@186813|unclassified Clostridiales	186801|Clostridia	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
k141_3405_29	946235.CAER01000074_gene579	0.0	888.0	COG0550@1|root,COG0550@2|Bacteria,1TPJD@1239|Firmicutes,4HAZV@91061|Bacilli,23K3F@182709|Oceanobacillus	91061|Bacilli	L	Bacterial DNA topoisomeraes I ATP-binding domain	-	-	5.99.1.2	ko:K03169	-	-	-	-	ko00000,ko01000,ko03032	-	-	-	Topoisom_bac,Toprim,Toprim_Crpt
k141_701_1	1265505.ATUG01000002_gene1132	9.5e-94	286.0	COG1914@1|root,COG1914@2|Bacteria,1MW6X@1224|Proteobacteria,42RRV@68525|delta/epsilon subdivisions,2WNKH@28221|Deltaproteobacteria,2MJB4@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Natural resistance-associated macrophage protein	-	-	-	-	-	-	-	-	-	-	-	-	Nramp
k141_702_1	879212.DespoDRAFT_02716	1.07e-150	432.0	COG2255@1|root,COG2255@2|Bacteria,1MU38@1224|Proteobacteria,42M99@68525|delta/epsilon subdivisions,2WJ2Q@28221|Deltaproteobacteria,2MHYU@213118|Desulfobacterales	28221|Deltaproteobacteria	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	-	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
k141_352_1	526224.Bmur_1026	1.31e-08	65.5	COG4399@1|root,COG4399@2|Bacteria,2JAD3@203691|Spirochaetes	203691|Spirochaetes	S	Belongs to the UPF0754 family	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_352_2	1286171.EAL2_c15140	1.99e-59	189.0	2CK8D@1|root,32SBU@2|Bacteria,1VAQG@1239|Firmicutes,24HSZ@186801|Clostridia	186801|Clostridia	S	Tryptophan transporter TrpP	trpP	-	-	-	-	-	-	-	-	-	-	iHN637.CLJU_RS14305	TrpP
k141_352_3	1391646.AVSU01000086_gene545	0.0	1054.0	COG2987@1|root,COG2987@2|Bacteria,1TPZ9@1239|Firmicutes,247YS@186801|Clostridia,25R5J@186804|Peptostreptococcaceae	186801|Clostridia	E	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate	hutU	-	4.2.1.49	ko:K01712	ko00340,ko01100,map00340,map01100	M00045	R02914	RC00804	ko00000,ko00001,ko00002,ko01000	-	-	-	Urocanase,Urocanase_C,Urocanase_N
k141_352_4	1292035.H476_1936	5.8e-151	431.0	COG3643@1|root,COG3643@2|Bacteria,1TP5T@1239|Firmicutes,24905@186801|Clostridia,25QZQ@186804|Peptostreptococcaceae	186801|Clostridia	E	Formiminotransferase domain, N-terminal subdomain	ftcD	-	2.1.2.5	ko:K00603	ko00340,ko00670,ko01100,map00340,map00670,map01100	-	R02287,R03189	RC00165,RC00221,RC00223,RC00870	ko00000,ko00001,ko01000	-	-	-	FTCD,FTCD_N
k141_352_5	1286171.EAL2_808p06020	3.63e-197	558.0	COG1228@1|root,COG1228@2|Bacteria,1TP2J@1239|Firmicutes,24AGR@186801|Clostridia,25Y7G@186806|Eubacteriaceae	186801|Clostridia	Q	Amidohydrolase family	hutI	-	3.5.2.7	ko:K01468	ko00340,ko01100,map00340,map01100	M00045	R02288	RC00683	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1,Amidohydro_3
k141_352_6	857293.CAAU_1751	7.91e-68	213.0	COG3404@1|root,COG3404@2|Bacteria,1V1X8@1239|Firmicutes,24JZM@186801|Clostridia,36JRA@31979|Clostridiaceae	186801|Clostridia	E	cyclohydrolase	fchA	-	4.3.1.4	ko:K01746	ko00670,ko01100,map00670,map01100	-	R02302	RC00688	ko00000,ko00001,ko01000	-	-	-	FTCD_C
k141_3406_1	760142.Hipma_0986	8.64e-17	81.6	COG1729@1|root,COG1729@2|Bacteria,1Q17D@1224|Proteobacteria,42WQ5@68525|delta/epsilon subdivisions,2WRU2@28221|Deltaproteobacteria,2M75T@213113|Desulfurellales	28221|Deltaproteobacteria	S	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division	cpoB	-	-	-	-	-	-	-	-	-	-	-	TPR_6
k141_3406_2	1121405.dsmv_2432	2.99e-44	150.0	COG0817@1|root,COG0817@2|Bacteria,1MUJI@1224|Proteobacteria,42QPX@68525|delta/epsilon subdivisions,2WNF9@28221|Deltaproteobacteria,2MJWT@213118|Desulfobacterales	28221|Deltaproteobacteria	L	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group	ruvC	GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576	3.1.22.4	ko:K01159	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvC
k141_3406_3	933262.AXAM01000015_gene86	1.03e-58	190.0	COG0632@1|root,COG0632@2|Bacteria,1Q5HB@1224|Proteobacteria,42R4Y@68525|delta/epsilon subdivisions,2WMRB@28221|Deltaproteobacteria,2MJPI@213118|Desulfobacterales	28221|Deltaproteobacteria	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB	ruvA	-	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_N
k141_1730_1	1348635.BBJY01000001_gene2474	2.02e-273	754.0	COG2710@1|root,COG2710@2|Bacteria,1MVY2@1224|Proteobacteria,1RSFD@1236|Gammaproteobacteria,1XZQE@135623|Vibrionales	135623|Vibrionales	C	Nitrogenase component 1 type Oxidoreductase	-	-	1.18.6.1	ko:K02586	ko00625,ko00910,ko01100,ko01120,map00625,map00910,map01100,map01120	M00175	R05185,R05496	RC00002,RC01395,RC02891	ko00000,ko00001,ko00002,ko01000	-	-	-	Oxidored_nitro
k141_4098_1	1219076.N646_0302	2.31e-15	70.1	2AWQN@1|root,31NMK@2|Bacteria,1QKC8@1224|Proteobacteria,1TIFR@1236|Gammaproteobacteria,1XZ1R@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_4098_3	945543.VIBR0546_17996	4.74e-11	58.9	2BBNH@1|root,3256H@2|Bacteria,1QKCP@1224|Proteobacteria,1TIG6@1236|Gammaproteobacteria,1XZ2Q@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	ko:K02651	ko04112,map04112	-	-	-	ko00000,ko00001,ko02035,ko02044	-	-	-	-
k141_4098_5	1348635.BBJY01000017_gene4137	5.45e-239	660.0	COG0152@1|root,COG0152@2|Bacteria,1MUR9@1224|Proteobacteria,1RNNY@1236|Gammaproteobacteria,1XUUI@135623|Vibrionales	135623|Vibrionales	F	Belongs to the SAICAR synthetase family	purC	GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.2.6	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04591	RC00064,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	SAICAR_synt
k141_4098_6	1051646.VITU9109_22236	2.47e-27	104.0	2BZUK@1|root,32RU7@2|Bacteria,1RM0J@1224|Proteobacteria,1S7RF@1236|Gammaproteobacteria,1XXI6@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_4098_7	55601.VANGNB10_cI1042c	1.09e-235	659.0	COG0281@1|root,COG0281@2|Bacteria,1MU0A@1224|Proteobacteria,1RQ11@1236|Gammaproteobacteria,1XTTY@135623|Vibrionales	135623|Vibrionales	C	malic enzyme	maeA	GO:0003674,GO:0003824,GO:0004470,GO:0004473,GO:0006082,GO:0006090,GO:0006108,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0019752,GO:0032787,GO:0043436,GO:0043648,GO:0044237,GO:0044281,GO:0055114,GO:0071704	1.1.1.38	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	-	R00214	RC00105	ko00000,ko00001,ko01000	-	-	-	Malic_M,malic
k141_2728_2	1191299.AJYX01000052_gene1526	9.17e-215	600.0	COG1283@1|root,COG1283@2|Bacteria,1MXWU@1224|Proteobacteria,1RP6R@1236|Gammaproteobacteria,1XUP0@135623|Vibrionales	135623|Vibrionales	P	COG1283 Na phosphate symporter	nptA	-	-	ko:K14683	-	-	-	-	ko00000,ko02000,ko04147	2.A.58.1	-	-	Na_Pi_cotrans
k141_2728_3	243277.VC_A0433	5.09e-09	63.9	COG0457@1|root,COG0457@2|Bacteria,1QXRG@1224|Proteobacteria,1T3HP@1236|Gammaproteobacteria,1Y35D@135623|Vibrionales	135623|Vibrionales	S	Protein of unknown function (DUF2971)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2971
k141_2728_4	1366050.N234_15280	5.93e-10	59.3	COG0207@1|root,COG0207@2|Bacteria,1MUBD@1224|Proteobacteria,2VIIR@28216|Betaproteobacteria,1K0Y1@119060|Burkholderiaceae	28216|Betaproteobacteria	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis	thyA	-	2.1.1.45	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	M00053	R02101	RC00219,RC00332	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylat_synt
k141_3408_1	1278307.KB906974_gene1806	6.55e-98	323.0	COG0642@1|root,COG0834@1|root,COG4251@1|root,COG0642@2|Bacteria,COG0834@2|Bacteria,COG2205@2|Bacteria,COG4251@2|Bacteria,1NRP8@1224|Proteobacteria,1SKTW@1236|Gammaproteobacteria,2QIRM@267894|Psychromonadaceae	1236|Gammaproteobacteria	T	ATP-binding region, ATPase domain protein domain protein	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	CHASE,GAF_2,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg,SBP_bac_3
k141_353_1	1304885.AUEY01000015_gene2997	4.92e-230	639.0	COG0535@1|root,COG0535@2|Bacteria,1MUQP@1224|Proteobacteria,42N9E@68525|delta/epsilon subdivisions,2WJAX@28221|Deltaproteobacteria,2MI1Z@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM Radical SAM domain protein	-	-	-	ko:K22226	-	-	-	-	ko00000	-	-	-	Fer4_12,Radical_SAM,SPASM
k141_2729_1	1121434.AULY01000006_gene638	0.00042	42.0	2E24Q@1|root,32XBS@2|Bacteria,1MZMP@1224|Proteobacteria,4362Z@68525|delta/epsilon subdivisions,2X0KU@28221|Deltaproteobacteria,2MCRK@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	P2 phage tail completion protein R (GpR)	-	-	-	-	-	-	-	-	-	-	-	-	P2_Phage_GpR
k141_2729_2	525146.Ddes_0245	1e-33	128.0	2BH8B@1|root,32B9K@2|Bacteria,1QHCD@1224|Proteobacteria,43EIH@68525|delta/epsilon subdivisions,2X0SB@28221|Deltaproteobacteria,2MD9C@213115|Desulfovibrionales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_1381_1	1348635.BBJY01000007_gene205	1.87e-70	228.0	COG0018@1|root,COG0018@2|Bacteria,1MU4J@1224|Proteobacteria,1RPRC@1236|Gammaproteobacteria,1XSVJ@135623|Vibrionales	135623|Vibrionales	J	Arginyl-tRNA synthetase	argS	GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
k141_1381_2	223926.28805846	2.1e-64	200.0	COG0537@1|root,COG0537@2|Bacteria,1MZVD@1224|Proteobacteria,1S9D9@1236|Gammaproteobacteria,1XX0J@135623|Vibrionales	135623|Vibrionales	FG	COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases	-	-	-	-	-	-	-	-	-	-	-	-	HIT
k141_1745_1	553385.JEMF01000020_gene3043	2.62e-39	149.0	COG1391@1|root,COG1391@2|Bacteria,1MU4I@1224|Proteobacteria,1RP9N@1236|Gammaproteobacteria,1XHKJ@135619|Oceanospirillales	135619|Oceanospirillales	OT	Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell	glnE	-	2.7.7.42,2.7.7.89	ko:K00982	-	-	-	-	ko00000,ko01000	-	-	-	GlnD_UR_UTase,GlnE
k141_724_1	760011.Spico_1611	1.96e-24	97.8	COG1725@1|root,COG1725@2|Bacteria,2J8Q8@203691|Spirochaetes	203691|Spirochaetes	K	Transcriptional regulator, GntR family	-	-	-	-	-	-	-	-	-	-	-	-	GntR
k141_3764_1	1123371.ATXH01000008_gene238	3.2e-114	345.0	COG1488@1|root,COG1488@2|Bacteria,2GGRR@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	H	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP	-	-	6.3.4.21	ko:K00763	ko00760,ko01100,map00760,map01100	-	R01724	RC00033	ko00000,ko00001,ko01000	-	-	-	NAPRTase
k141_3764_2	706587.Desti_1705	5.24e-21	86.3	COG2840@1|root,COG2840@2|Bacteria,1QX48@1224|Proteobacteria,43BWQ@68525|delta/epsilon subdivisions,2X77I@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Smr domain	-	-	-	-	-	-	-	-	-	-	-	-	Smr
k141_2386_1	1191299.AJYX01000034_gene2958	2.18e-06	46.2	2AWXY@1|root,31NVK@2|Bacteria,1QKJ8@1224|Proteobacteria,1TIPI@1236|Gammaproteobacteria,1XZF5@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_2386_2	1219076.N646_2937	5.95e-197	554.0	COG1344@1|root,COG1344@2|Bacteria,1MV1N@1224|Proteobacteria,1RN0Y@1236|Gammaproteobacteria,1XSDK@135623|Vibrionales	135623|Vibrionales	N	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella	flaD	GO:0005575,GO:0005576,GO:0005623,GO:0009288,GO:0042995,GO:0043226,GO:0043228,GO:0044464	-	ko:K02406	ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flagellin_C,Flagellin_IN,Flagellin_N
k141_2386_3	1042375.AFPL01000006_gene2944	7.21e-41	136.0	2CZ7C@1|root,32T5R@2|Bacteria,1N0CN@1224|Proteobacteria,1S9C8@1236|Gammaproteobacteria,468D8@72275|Alteromonadaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_2386_4	1219080.VEZ01S_16_00420	2.39e-122	353.0	COG0863@1|root,COG0863@2|Bacteria,1R7KV@1224|Proteobacteria,1RZ25@1236|Gammaproteobacteria,1XUTY@135623|Vibrionales	135623|Vibrionales	L	DNA methylase	VP0394	-	2.1.1.72	ko:K00571	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	N6_N4_Mtase
k141_2386_5	56110.Oscil6304_2230	2.91e-34	122.0	COG4994@1|root,COG4994@2|Bacteria,1G6FZ@1117|Cyanobacteria,1HBEP@1150|Oscillatoriales	1117|Cyanobacteria	S	Domain of unknown function (DUF4440)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440
k141_2386_6	526222.Desal_0962	3.33e-98	293.0	COG1073@1|root,COG1073@2|Bacteria,1P3KF@1224|Proteobacteria,42UHM@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	Alpha/beta hydrolase family	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	-
k141_3840_21	675813.VIB_001828	1.54e-139	406.0	COG4188@1|root,COG4188@2|Bacteria,1MW6H@1224|Proteobacteria,1RSGW@1236|Gammaproteobacteria,1Y28E@135623|Vibrionales	135623|Vibrionales	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4
k141_3840_22	575788.VS_II1201	8.16e-100	306.0	COG4977@1|root,COG4977@2|Bacteria,1R01Y@1224|Proteobacteria,1T4DW@1236|Gammaproteobacteria,1Y38N@135623|Vibrionales	135623|Vibrionales	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
k141_3840_23	314292.VAS14_10844	2.08e-46	157.0	2DT7B@1|root,33J0R@2|Bacteria,1NKDX@1224|Proteobacteria,1SGB3@1236|Gammaproteobacteria,1XX4N@135623|Vibrionales	135623|Vibrionales	S	Protein of unknown function (DUF2975)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2975
k141_3840_24	1191299.AJYX01000009_gene137	7.59e-34	117.0	COG3655@1|root,COG3655@2|Bacteria,1N6VH@1224|Proteobacteria,1SDAJ@1236|Gammaproteobacteria,1XYXN@135623|Vibrionales	135623|Vibrionales	K	Transcriptional regulator	BT2546	-	-	ko:K07727	-	-	-	-	ko00000,ko03000	-	-	-	HTH_26
k141_3840_25	1238450.VIBNISOn1_1540070	8.21e-116	338.0	COG1122@1|root,COG1122@2|Bacteria,1N5X0@1224|Proteobacteria,1SZ03@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	ATPases associated with a variety of cellular activities	-	-	-	ko:K02006,ko:K16784	ko02010,map02010	M00245,M00246,M00581	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.18,3.A.1.22,3.A.1.23,3.A.1.25.1	-	-	ABC_tran
k141_3840_26	1122207.MUS1_02070	1.63e-88	265.0	COG0619@1|root,COG0619@2|Bacteria,1RCBK@1224|Proteobacteria,1S3HQ@1236|Gammaproteobacteria,1XMFI@135619|Oceanospirillales	135619|Oceanospirillales	P	Cobalt transport protein	-	-	-	-	-	-	-	-	-	-	-	-	CbiQ
k141_522_1	1304885.AUEY01000008_gene2096	2.14e-18	93.2	COG0643@1|root,COG0643@2|Bacteria	2|Bacteria	T	phosphorelay sensor kinase activity	-	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt
k141_4559_1	55601.VANGNB10_cII0139	1.53e-119	352.0	COG2223@1|root,COG2223@2|Bacteria,1MW71@1224|Proteobacteria,1RN10@1236|Gammaproteobacteria,1XSI0@135623|Vibrionales	135623|Vibrionales	P	COG0477 Permeases of the major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
k141_4559_2	1485545.JQLW01000005_gene1024	8.37e-42	141.0	2DMKI@1|root,32S70@2|Bacteria,1N1FV@1224|Proteobacteria	1224|Proteobacteria	S	SpoIIAA-like	VVA0543	-	-	-	-	-	-	-	-	-	-	-	SpoIIAA-like
k141_4559_4	595494.Tola_1293	3.41e-77	233.0	COG1432@1|root,COG1432@2|Bacteria,1MUAE@1224|Proteobacteria,1S47Z@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Nuclease	-	-	-	-	-	-	-	-	-	-	-	-	NYN
k141_4559_6	1208321.D104_03015	5.55e-135	392.0	COG0583@1|root,COG0583@2|Bacteria,1R4QT@1224|Proteobacteria,1RR79@1236|Gammaproteobacteria,1XHUU@135619|Oceanospirillales	135619|Oceanospirillales	K	transcriptional regulator	-	-	-	ko:K21645	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,LysR_substrate
k141_4559_7	1208321.D104_03020	2.39e-59	193.0	COG4608@1|root,COG4608@2|Bacteria,1NU4K@1224|Proteobacteria,1SKPD@1236|Gammaproteobacteria,1XIS0@135619|Oceanospirillales	135619|Oceanospirillales	P	the ABC transporter	-	-	-	ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
k141_1830_1	879212.DespoDRAFT_02978	2.5e-62	211.0	COG3605@1|root,COG3605@2|Bacteria,1QTTV@1224|Proteobacteria,42PST@68525|delta/epsilon subdivisions,2WJ3A@28221|Deltaproteobacteria,2MIS5@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Belongs to the PEP-utilizing enzyme family	ptsP	-	2.7.3.9	ko:K08484	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	-	-	-	GAF_2,PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C
k141_2141_1	1536774.H70357_33940	6.13e-59	193.0	COG3878@1|root,COG3878@2|Bacteria	2|Bacteria	J	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF1963
k141_769_2	1348635.BBJY01000008_gene1801	0.0	1105.0	COG0744@1|root,COG0744@2|Bacteria,1QTST@1224|Proteobacteria,1RNHV@1236|Gammaproteobacteria,1XVGW@135623|Vibrionales	135623|Vibrionales	M	Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)	mrcB	GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	2.4.1.129,3.4.16.4	ko:K05365	ko00550,map00550	-	R04519	RC00005,RC00049	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase,UB2H
k141_769_3	617140.AJZE01000023_gene86	0.0	915.0	COG1643@1|root,COG1643@2|Bacteria,1MUEQ@1224|Proteobacteria,1RR1B@1236|Gammaproteobacteria,1XTYU@135623|Vibrionales	135623|Vibrionales	L	ATP-dependent RNA helicase	hrpB	-	3.6.4.13	ko:K03579	-	-	-	-	ko00000,ko01000	-	-	-	DEAD,HA2,Helicase_C,HrpB_C
k141_1831_1	585.DR95_2066	8.74e-86	271.0	COG3604@1|root,COG3604@2|Bacteria,1QTT3@1224|Proteobacteria,1T1G7@1236|Gammaproteobacteria,3Z0V5@583|Proteus	1236|Gammaproteobacteria	KT	Domain present in phytochromes and cGMP-specific phosphodiesterases.	hyfR	GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006139,GO:0006351,GO:0006352,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031326,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043254,GO:0044087,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1903506,GO:2000112,GO:2000142,GO:2001141	-	ko:K12146,ko:K15836	-	-	-	-	ko00000,ko03000	-	-	-	GAF,GAF_2,HTH_8,Sigma54_activat
k141_4560_1	1121438.JNJA01000006_gene167	5.29e-96	297.0	COG4773@1|root,COG4773@2|Bacteria,1QCTH@1224|Proteobacteria,42PPC@68525|delta/epsilon subdivisions,2WIS8@28221|Deltaproteobacteria,2MAAG@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	Receptor	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_2783_1	674977.VMC_28420	2.6e-192	538.0	COG0332@1|root,COG0332@2|Bacteria,1MU9N@1224|Proteobacteria,1RNIR@1236|Gammaproteobacteria,1XTK6@135623|Vibrionales	135623|Vibrionales	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:0072330,GO:1901576	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
k141_2783_2	55601.VANGNB10_cI1837c	1.53e-190	535.0	COG0416@1|root,COG0416@2|Bacteria,1MVM3@1224|Proteobacteria,1RM7R@1236|Gammaproteobacteria,1XU27@135623|Vibrionales	135623|Vibrionales	I	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA	plsX	GO:0003674,GO:0003824,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0044238,GO:0071704,GO:1901576	2.3.1.15	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FA_synthesis
k141_2783_4	1051646.VITU9109_01002	3.83e-94	278.0	COG1399@1|root,COG1399@2|Bacteria,1PGKW@1224|Proteobacteria,1RRK3@1236|Gammaproteobacteria,1XTCK@135623|Vibrionales	135623|Vibrionales	S	metal-binding, possibly nucleic acid-binding protein	yceD	-	-	ko:K07040	-	-	-	-	ko00000	-	-	-	DUF177
k141_2783_5	1136163.M565_ctg1P0559	2.05e-85	257.0	COG0424@1|root,COG0424@2|Bacteria,1RDA9@1224|Proteobacteria,1S3TQ@1236|Gammaproteobacteria,1XUK8@135623|Vibrionales	135623|Vibrionales	D	COG0424 Nucleotide-binding protein implicated in inhibition of septum formation	yceF	-	-	-	-	-	-	-	-	-	-	-	Maf
k141_2783_6	945543.VIBR0546_02119	2.86e-179	504.0	COG0564@1|root,COG0564@2|Bacteria,1MVDX@1224|Proteobacteria,1RPAN@1236|Gammaproteobacteria,1XT4V@135623|Vibrionales	135623|Vibrionales	J	Responsible for synthesis of pseudouridine from uracil	rluC	GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	5.4.99.24	ko:K06179	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
k141_2783_7	1116375.VEJY3_10725	0.0	1009.0	COG1530@1|root,COG1530@2|Bacteria,1MV65@1224|Proteobacteria,1RMDS@1236|Gammaproteobacteria,1XTUQ@135623|Vibrionales	135623|Vibrionales	J	Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs	rne	-	3.1.26.12	ko:K08300	ko03018,map03018	M00394	-	-	ko00000,ko00001,ko00002,ko01000,ko03009,ko03019	-	-	-	RNase_E_G,S1
k141_3841_2	590409.Dd586_1279	1.71e-54	191.0	COG3209@1|root,COG3209@2|Bacteria,1MVV1@1224|Proteobacteria,1SKYM@1236|Gammaproteobacteria,2JEQ6@204037|Dickeya	1236|Gammaproteobacteria	M	TIGRFAM YD repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF4150,PAAR_motif,RHS,RHS_repeat,Tox-HNH-EHHH
k141_3841_3	634499.EpC_04530	3.99e-28	108.0	2E36B@1|root,32Y62@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_1149_1	439235.Dalk_3481	5.28e-295	837.0	COG0458@1|root,COG0458@2|Bacteria,1MUDZ@1224|Proteobacteria,42MGK@68525|delta/epsilon subdivisions,2WJQH@28221|Deltaproteobacteria,2MHQD@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Carbamoyl-phosphate synthetase large chain oligomerisation	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
k141_1149_2	1304885.AUEY01000020_gene3516	4.4e-109	326.0	COG0505@1|root,COG0505@2|Bacteria,1MUB9@1224|Proteobacteria,42KZG@68525|delta/epsilon subdivisions,2WIQ5@28221|Deltaproteobacteria,2MIKI@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Belongs to the CarA family	carA	-	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_sm_chain,GATase
k141_5160_1	675814.VIC_002521	4.08e-145	434.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RWMH@1236|Gammaproteobacteria,1XUY3@135623|Vibrionales	135623|Vibrionales	T	GGDEF family	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
k141_5160_2	1348635.BBJY01000010_gene1272	2.11e-181	520.0	COG0739@1|root,COG1388@1|root,COG0739@2|Bacteria,COG1388@2|Bacteria,1MVTF@1224|Proteobacteria,1RM7S@1236|Gammaproteobacteria,1XSZJ@135623|Vibrionales	135623|Vibrionales	M	COG0739 Membrane proteins related to metalloendopeptidases	-	-	-	-	-	-	-	-	-	-	-	-	OapA,Peptidase_M23
k141_5160_3	345073.VC395_A0072	1.23e-46	152.0	COG0296@1|root,COG0296@2|Bacteria,1N8WX@1224|Proteobacteria,1SG9V@1236|Gammaproteobacteria,1XY0F@135623|Vibrionales	135623|Vibrionales	G	PFAM glycoside hydrolase, family 13	-	-	-	-	-	-	-	-	-	-	-	-	AMPK1_CBM
k141_5160_4	617140.AJZE01000072_gene909	9.69e-218	613.0	COG3314@1|root,COG3314@2|Bacteria,1NEAN@1224|Proteobacteria,1RPX6@1236|Gammaproteobacteria,1XTQR@135623|Vibrionales	135623|Vibrionales	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	Gate
k141_5160_5	1121445.ATUZ01000014_gene1393	2.19e-05	48.1	COG0607@1|root,COG0607@2|Bacteria,1Q5KY@1224|Proteobacteria,42WYK@68525|delta/epsilon subdivisions,2WQQW@28221|Deltaproteobacteria,2MDQK@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	PFAM Rhodanese domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
k141_5160_6	454957.IA64_04945	1.25e-99	301.0	COG0583@1|root,COG0583@2|Bacteria,1MWUP@1224|Proteobacteria,1RNIC@1236|Gammaproteobacteria,1X9RV@135614|Xanthomonadales	135614|Xanthomonadales	K	transcriptional regulator	iciA	-	-	ko:K05596	-	-	-	-	ko00000,ko03000,ko03036	-	-	-	HTH_1,LysR_substrate
k141_5160_7	316273.XCV3263	1.13e-62	200.0	COG1279@1|root,COG1279@2|Bacteria,1RD6B@1224|Proteobacteria,1RR03@1236|Gammaproteobacteria,1X7E6@135614|Xanthomonadales	135614|Xanthomonadales	S	LysE type translocator	yggA	-	-	ko:K06895	-	-	-	-	ko00000,ko02000	2.A.75.1	-	-	LysE
k141_182_39	1219065.VPR01S_09_00730	0.0	1317.0	COG0460@1|root,COG0527@1|root,COG0460@2|Bacteria,COG0527@2|Bacteria,1MW3H@1224|Proteobacteria,1RN1G@1236|Gammaproteobacteria,1XU62@135623|Vibrionales	135623|Vibrionales	E	Bifunctional aspartokinase I homoserine dehydrogenase I	thrA	-	1.1.1.3,2.7.2.4	ko:K12524	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00017,M00018,M00526,M00527	R00480,R01773,R01775	RC00002,RC00043,RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT,ACT_7,Homoserine_dh,NAD_binding_3
k141_182_40	675815.VOA_002687	1.33e-75	229.0	COG0684@1|root,COG0684@2|Bacteria,1RH18@1224|Proteobacteria,1RS9U@1236|Gammaproteobacteria,1XX44@135623|Vibrionales	135623|Vibrionales	H	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions	-	-	-	ko:K02553	-	-	-	-	ko00000,ko03019	-	-	-	RraA-like
k141_182_41	672.VV93_v1c05860	3.34e-25	100.0	2DRAF@1|root,33AYA@2|Bacteria,1NGMJ@1224|Proteobacteria,1SGEB@1236|Gammaproteobacteria,1XYBY@135623|Vibrionales	135623|Vibrionales	S	Protein of unknown function (DUF3293)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3293
k141_182_42	575788.VS_0479	3.02e-144	412.0	COG0745@1|root,COG0745@2|Bacteria,1MWJG@1224|Proteobacteria,1RPU3@1236|Gammaproteobacteria,1XV50@135623|Vibrionales	135623|Vibrionales	K	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	arcA	-	-	ko:K07773	ko02020,ko02026,map02020,map02026	M00456	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
k141_182_44	55601.VANGNB10_cI2145c	0.0	1125.0	COG0642@1|root,COG0745@1|root,COG2198@1|root,COG0745@2|Bacteria,COG2198@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,1SKTW@1236|Gammaproteobacteria,1XSC0@135623|Vibrionales	135623|Vibrionales	T	aerobic respiration control sensor protein	arcB	-	2.7.13.3	ko:K07648	ko02020,ko02026,map02020,map02026	M00456	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,Hpt,PAS,PAS_4,Response_reg
k141_182_45	223926.28805468	2.2e-192	538.0	COG1242@1|root,COG1242@2|Bacteria,1MUYF@1224|Proteobacteria,1RP94@1236|Gammaproteobacteria,1XSN0@135623|Vibrionales	135623|Vibrionales	S	Radical_SAM C-terminal domain	yhcC	-	-	ko:K07139	-	-	-	-	ko00000	-	-	-	Radical_SAM,Radical_SAM_C
k141_182_48	675815.VOA_002695	0.0	2394.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1MU7B@1224|Proteobacteria,1RN2W@1236|Gammaproteobacteria,1XSWZ@135623|Vibrionales	135623|Vibrionales	E	Glutamate synthase	gltB	-	1.4.1.13,1.4.1.14	ko:K00265	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
k141_182_49	672.VV93_v1c05770	7.34e-275	759.0	COG0493@1|root,COG0493@2|Bacteria,1MU2H@1224|Proteobacteria,1RMY7@1236|Gammaproteobacteria,1XV02@135623|Vibrionales	135623|Vibrionales	C	COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases	gltD	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	Fer4_20,Pyr_redox_2
k141_182_50	1219077.VAZ01S_038_00380	1.44e-125	362.0	COG0775@1|root,COG0775@2|Bacteria,1MY5S@1224|Proteobacteria,1RNSF@1236|Gammaproteobacteria,1XTZ2@135623|Vibrionales	135623|Vibrionales	F	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively	mtnN	GO:0003674,GO:0003824,GO:0008477,GO:0008782,GO:0008930,GO:0016787,GO:0016798,GO:0016799	3.2.2.9	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	M00034,M00609	R00194,R01401	RC00063,RC00318	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
k141_182_51	675806.VII_001478	1.23e-111	333.0	COG1270@1|root,COG1270@2|Bacteria,1MURM@1224|Proteobacteria,1S6W4@1236|Gammaproteobacteria,1XSVK@135623|Vibrionales	135623|Vibrionales	H	COG1270 Cobalamin biosynthesis protein CobD CbiB	-	-	6.3.1.10	ko:K02227	ko00860,ko01100,map00860,map01100	M00122	R06529,R07302	RC00090,RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	CobD_Cbib
k141_182_52	1280001.BAOA01000021_gene928	3.39e-115	333.0	COG2860@1|root,COG2860@2|Bacteria,1RHQN@1224|Proteobacteria,1S5YY@1236|Gammaproteobacteria,1XV4W@135623|Vibrionales	135623|Vibrionales	S	membrane	yadS	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	UPF0126
k141_182_53	945550.VISI1226_02662	4.46e-275	759.0	COG3104@1|root,COG3104@2|Bacteria,1MW6W@1224|Proteobacteria,1RM8P@1236|Gammaproteobacteria,1XTDG@135623|Vibrionales	135623|Vibrionales	U	COG3104 Dipeptide tripeptide permease	-	-	-	ko:K03305	-	-	-	-	ko00000	2.A.17	-	-	PTR2
k141_182_55	675815.VOA_002702	1.77e-119	348.0	COG0730@1|root,COG0730@2|Bacteria,1MXNM@1224|Proteobacteria,1RRH4@1236|Gammaproteobacteria,1XSXB@135623|Vibrionales	135623|Vibrionales	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
k141_182_56	223926.28805454	0.0	1936.0	COG0458@1|root,COG0458@2|Bacteria,1MUDZ@1224|Proteobacteria,1RPIU@1236|Gammaproteobacteria,1XSNU@135623|Vibrionales	135623|Vibrionales	F	Carbamoyl-phosphate synthetase ammonia chain	carB	GO:0000050,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006220,GO:0006221,GO:0006520,GO:0006525,GO:0006526,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019627,GO:0019637,GO:0019693,GO:0019752,GO:0034641,GO:0034654,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046390,GO:0046394,GO:0046483,GO:0055086,GO:0071704,GO:0071941,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
k141_182_57	29495.EA26_03245	2.56e-252	694.0	COG0505@1|root,COG0505@2|Bacteria,1MUB9@1224|Proteobacteria,1RMAW@1236|Gammaproteobacteria,1XV0G@135623|Vibrionales	135623|Vibrionales	F	carbamoyl-phosphate synthetase glutamine chain	carA	GO:0000050,GO:0003674,GO:0003824,GO:0004088,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005951,GO:0006082,GO:0006139,GO:0006220,GO:0006221,GO:0006520,GO:0006525,GO:0006526,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019627,GO:0019637,GO:0019693,GO:0019752,GO:0032991,GO:0034641,GO:0034654,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046394,GO:0046483,GO:0055086,GO:0071704,GO:0071941,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_sm_chain,GATase
k141_182_58	1348635.BBJY01000002_gene3575	4.49e-160	452.0	COG0289@1|root,COG0289@2|Bacteria,1MUCT@1224|Proteobacteria,1RMCZ@1236|Gammaproteobacteria,1XU3A@135623|Vibrionales	135623|Vibrionales	E	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate	dapB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	-	DapB_C,DapB_N
k141_182_59	55601.VANGNB10_cI2161c	1.8e-59	186.0	COG0494@1|root,COG0494@2|Bacteria,1RCZM@1224|Proteobacteria,1RS3S@1236|Gammaproteobacteria,1XXA4@135623|Vibrionales	135623|Vibrionales	L	Belongs to the Nudix hydrolase family	mutT	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
k141_182_60	55601.VANGNB10_cI2162c	0.0	1471.0	COG0653@1|root,COG0653@2|Bacteria,1MUJZ@1224|Proteobacteria,1RM9M@1236|Gammaproteobacteria,1XTFQ@135623|Vibrionales	135623|Vibrionales	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	GO:0000166,GO:0002790,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032940,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
k141_182_62	55601.VANGNB10_cI2165c	1.11e-232	647.0	COG0206@1|root,COG0206@2|Bacteria,1MV2X@1224|Proteobacteria,1RPZS@1236|Gammaproteobacteria,1XTKI@135623|Vibrionales	135623|Vibrionales	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
k141_182_63	55601.VANGNB10_cI2166c	2.59e-276	759.0	COG0849@1|root,COG0849@2|Bacteria,1MUSR@1224|Proteobacteria,1RMXY@1236|Gammaproteobacteria,1XVP9@135623|Vibrionales	135623|Vibrionales	D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring	ftsA	-	-	ko:K03590	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036,ko04812	-	-	-	FtsA,SHS2_FTSA
k141_182_64	945550.VISI1226_07642	4.29e-123	358.0	COG1589@1|root,COG1589@2|Bacteria,1N0T7@1224|Proteobacteria,1S9FJ@1236|Gammaproteobacteria,1XTAJ@135623|Vibrionales	135623|Vibrionales	D	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly	ftsQ	-	-	ko:K03589	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036	-	-	-	FtsQ,POTRA_1
k141_182_65	223926.28805444	4.35e-305	837.0	COG0773@1|root,COG0773@2|Bacteria,1MV68@1224|Proteobacteria,1RN88@1236|Gammaproteobacteria,1XTZ7@135623|Vibrionales	135623|Vibrionales	M	Belongs to the MurCDEF family	murC	GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008763,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
k141_182_66	223926.28805443	1.31e-195	549.0	COG0707@1|root,COG0707@2|Bacteria,1MVIB@1224|Proteobacteria,1RMQ3@1236|Gammaproteobacteria,1XSDU@135623|Vibrionales	135623|Vibrionales	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
k141_182_68	243277.VC_2403	7.34e-215	606.0	COG0771@1|root,COG0771@2|Bacteria,1MVYD@1224|Proteobacteria,1RP25@1236|Gammaproteobacteria,1XUNN@135623|Vibrionales	135623|Vibrionales	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008764,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_C,Mur_ligase_M
k141_182_69	55601.VANGNB10_cI2172c	4.93e-229	634.0	COG0472@1|root,COG0472@2|Bacteria,1MUTK@1224|Proteobacteria,1RNIG@1236|Gammaproteobacteria,1XSMD@135623|Vibrionales	135623|Vibrionales	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008963,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016740,GO:0016772,GO:0016780,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	-	Glycos_transf_4,MraY_sig1
k141_182_70	675813.VIB_001968	4.61e-211	596.0	COG0770@1|root,COG0770@2|Bacteria,1QTSF@1224|Proteobacteria,1RMGD@1236|Gammaproteobacteria,1XUMH@135623|Vibrionales	135623|Vibrionales	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
k141_182_71	243277.VC_2406	3.12e-218	619.0	COG0769@1|root,COG0769@2|Bacteria,1MU6P@1224|Proteobacteria,1RMD6@1236|Gammaproteobacteria,1XUJ7@135623|Vibrionales	135623|Vibrionales	M	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
k141_182_72	55601.VANGNB10_cI2175c	3.08e-300	832.0	COG0768@1|root,COG0768@2|Bacteria,1MUNY@1224|Proteobacteria,1RNGW@1236|Gammaproteobacteria,1XTH5@135623|Vibrionales	135623|Vibrionales	D	Catalyzes cross-linking of the peptidoglycan cell wall at the division septum	ftsI	-	3.4.16.4	ko:K03587	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PBP_dimer,Transpeptidase
k141_182_73	675813.VIB_001971	1.18e-39	134.0	COG3116@1|root,COG3116@2|Bacteria,1N9MH@1224|Proteobacteria,1SC7P@1236|Gammaproteobacteria,1XXXH@135623|Vibrionales	135623|Vibrionales	D	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic	ftsL	-	-	ko:K03586	-	-	-	-	ko00000,ko03036	-	-	-	FtsL
k141_182_74	672.VV93_v1c05490	6.65e-193	539.0	COG0275@1|root,COG0275@2|Bacteria,1MUT4@1224|Proteobacteria,1RM7M@1236|Gammaproteobacteria,1XU1Z@135623|Vibrionales	135623|Vibrionales	J	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
k141_182_75	55601.VANGNB10_cI2178c	5e-165	466.0	COG0313@1|root,COG0313@2|Bacteria,1MU0E@1224|Proteobacteria,1RM7U@1236|Gammaproteobacteria,1XU78@135623|Vibrionales	135623|Vibrionales	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA	rsmI	GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
k141_182_76	675815.VOA_003266	1.61e-240	683.0	COG3107@1|root,COG3107@2|Bacteria,1MUHR@1224|Proteobacteria,1RXX4@1236|Gammaproteobacteria,1XT66@135623|Vibrionales	135623|Vibrionales	M	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a)	lpoA	-	-	ko:K07121	-	-	-	-	ko00000	-	-	-	LppC
k141_182_77	520999.PROVALCAL_02180	1.8e-22	92.4	COG0792@1|root,COG0792@2|Bacteria,1N6VN@1224|Proteobacteria,1SC8A@1236|Gammaproteobacteria,3Z976@586|Providencia	1236|Gammaproteobacteria	L	Belongs to the UPF0102 family	yraN	-	-	ko:K07460	-	-	-	-	ko00000	-	-	-	UPF0102
k141_182_78	1280001.BAOA01000021_gene902	6.14e-123	352.0	COG0279@1|root,COG0279@2|Bacteria,1NJ8X@1224|Proteobacteria,1RS1Y@1236|Gammaproteobacteria,1XUEU@135623|Vibrionales	135623|Vibrionales	G	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate	diaA	-	-	ko:K12961	-	-	-	-	ko00000,ko03036	-	-	-	SIS_2
k141_182_79	945550.VISI1226_07562	2.56e-70	218.0	COG2823@1|root,COG2823@2|Bacteria,1MUZ2@1224|Proteobacteria,1RY2B@1236|Gammaproteobacteria,1XVEM@135623|Vibrionales	135623|Vibrionales	S	periplasmic or secreted lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	BON
k141_182_80	1219065.VPR01S_21_00710	2.62e-70	216.0	COG2969@1|root,COG2969@2|Bacteria,1MZ2Q@1224|Proteobacteria,1S8WT@1236|Gammaproteobacteria,1XWV9@135623|Vibrionales	135623|Vibrionales	S	stringent starvation protein b	sspB	-	-	ko:K03600	-	-	-	-	ko00000,ko03021	-	-	-	SspB
k141_182_84	1348635.BBJY01000002_gene3607	1.16e-67	208.0	COG3105@1|root,COG3105@2|Bacteria,1N25P@1224|Proteobacteria,1S7WW@1236|Gammaproteobacteria,1XXEQ@135623|Vibrionales	135623|Vibrionales	S	protein conserved in bacteria	yhcB	-	-	ko:K09908	-	-	-	-	ko00000	-	-	-	DUF1043
k141_182_86	870967.VIS19158_04963	5.61e-198	555.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,1RN9T@1236|Gammaproteobacteria,1XTPV@135623|Vibrionales	135623|Vibrionales	O	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain	degS	-	-	ko:K04691	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Trypsin_2
k141_182_92	1051646.VITU9109_25860	3.81e-125	363.0	COG4137@1|root,COG4137@2|Bacteria,1R3YD@1224|Proteobacteria,1RPUQ@1236|Gammaproteobacteria,1XSTU@135623|Vibrionales	135623|Vibrionales	S	transport system, permease component	ypjD	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm
k141_182_93	243277.VC_0558	6.8e-253	700.0	COG4536@1|root,COG4536@2|Bacteria,1NZ99@1224|Proteobacteria,1RNCE@1236|Gammaproteobacteria,1XTJ9@135623|Vibrionales	135623|Vibrionales	P	Mg2 and Co2 transporter CorB	yfjD	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,DUF21
k141_182_94	1249634.D781_1737	8.94e-214	606.0	COG0168@1|root,COG0168@2|Bacteria,1MUIJ@1224|Proteobacteria,1RQNY@1236|Gammaproteobacteria,402T9@613|Serratia	1236|Gammaproteobacteria	P	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA	trkG	GO:0003674,GO:0005215,GO:0005216,GO:0005261,GO:0005267,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015267,GO:0015318,GO:0015672,GO:0016020,GO:0016021,GO:0022803,GO:0022838,GO:0022857,GO:0022890,GO:0030001,GO:0030955,GO:0031224,GO:0031226,GO:0031420,GO:0034220,GO:0043167,GO:0043169,GO:0044425,GO:0044459,GO:0044464,GO:0046872,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0098655,GO:0098660,GO:0098662	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	iECDH1ME8569_1439.ECDH1ME8569_1308	TrkH
k141_182_96	1191299.AJYX01000063_gene545	2.08e-74	228.0	COG4764@1|root,COG4764@2|Bacteria,1MVRK@1224|Proteobacteria,1RQ79@1236|Gammaproteobacteria,1XTVN@135623|Vibrionales	135623|Vibrionales	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_182_97	55601.VANGNB10_cI0459	3.22e-253	709.0	COG2918@1|root,COG2918@2|Bacteria,1MW9B@1224|Proteobacteria,1RPNQ@1236|Gammaproteobacteria,1XTNN@135623|Vibrionales	135623|Vibrionales	H	Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily	gshA	GO:0003674,GO:0003824,GO:0004357,GO:0006518,GO:0006575,GO:0006749,GO:0006750,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0019184,GO:0034641,GO:0042398,GO:0043043,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0051186,GO:0051188,GO:0071704,GO:1901564,GO:1901566,GO:1901576	6.3.2.2	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	M00118	R00894,R10993	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	Glu_cys_ligase
k141_182_98	55601.VANGNB10_cI0458	0.0	1159.0	COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,1RN05@1236|Gammaproteobacteria,1XU3E@135623|Vibrionales	135623|Vibrionales	S	Insulinase (Peptidase family M16)	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
k141_182_99	1219065.VPR01S_09_01760	2.65e-56	179.0	COG1238@1|root,COG1238@2|Bacteria,1RHUV@1224|Proteobacteria,1S4XE@1236|Gammaproteobacteria,1XX13@135623|Vibrionales	135623|Vibrionales	S	membrane	yqaA	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
k141_182_100	945550.VISI1226_22670	2.25e-175	494.0	COG0604@1|root,COG0604@2|Bacteria,1MX8A@1224|Proteobacteria,1RV93@1236|Gammaproteobacteria,1XTAN@135623|Vibrionales	135623|Vibrionales	C	COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases	-	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N_2
k141_182_102	672.VV93_v1c25100	0.0	926.0	COG0511@1|root,COG5016@1|root,COG0511@2|Bacteria,COG5016@2|Bacteria,1QTTG@1224|Proteobacteria,1RNG6@1236|Gammaproteobacteria,1XT1B@135623|Vibrionales	135623|Vibrionales	CI	oxaloacetate	oadA	-	4.1.1.3	ko:K01571	ko00620,ko01100,map00620,map01100	-	R00217	RC00040	ko00000,ko00001,ko01000,ko02000	3.B.1.1.1	-	-	Biotin_lipoyl,HMGL-like,PYC_OADA
k141_182_103	1191299.AJYX01000063_gene538	1.35e-20	85.5	COG3630@1|root,COG3630@2|Bacteria,1NHYS@1224|Proteobacteria,1SG6X@1236|Gammaproteobacteria,1XYD5@135623|Vibrionales	135623|Vibrionales	C	Lyase and sodium transporter	oadG	GO:0003674,GO:0003824,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008150,GO:0008948,GO:0015672,GO:0016829,GO:0016830,GO:0016831,GO:0030001,GO:0051179,GO:0051234	4.1.1.3	ko:K01573	ko00620,ko01100,map00620,map01100	-	R00217	RC00040	ko00000,ko00001,ko01000,ko02000	3.B.1.1.1	-	-	OAD_gamma
k141_182_104	1279015.KB908454_gene791	1.14e-31	111.0	COG1551@1|root,COG1551@2|Bacteria,1N6PG@1224|Proteobacteria,1SCB4@1236|Gammaproteobacteria,1Y4R5@135624|Aeromonadales	135624|Aeromonadales	J	A key translational regulator that binds mRNA to regulate translation initiation and or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'- UTR	csrA	-	-	ko:K03563	ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03019	-	-	-	CsrA
k141_182_105	29495.EA26_18455	0.0	1399.0	COG0013@1|root,COG0013@2|Bacteria,1MU9A@1224|Proteobacteria,1RMWZ@1236|Gammaproteobacteria,1XUIK@135623|Vibrionales	135623|Vibrionales	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
k141_182_106	674977.VMC_08070	7.4e-60	189.0	COG2137@1|root,COG2137@2|Bacteria,1N6P6@1224|Proteobacteria,1SCMF@1236|Gammaproteobacteria,1XWKA@135623|Vibrionales	135623|Vibrionales	S	Modulates RecA activity	recX	GO:0006282,GO:0008150,GO:0019219,GO:0019222,GO:0031323,GO:0048583,GO:0050789,GO:0050794,GO:0051052,GO:0051171,GO:0060255,GO:0065007,GO:0080090,GO:0080134,GO:0080135,GO:2001020	-	ko:K03565	-	-	-	-	ko00000,ko03400	-	-	-	RecX
k141_182_107	28444.JODQ01000001_gene2452	1.72e-12	76.6	COG0657@1|root,COG0657@2|Bacteria,2GJYR@201174|Actinobacteria,4EH0M@85012|Streptosporangiales	201174|Actinobacteria	I	Carboxylesterase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3
k141_182_108	345073.VC395_0560	2.19e-228	634.0	COG0468@1|root,COG0468@2|Bacteria,1MU3C@1224|Proteobacteria,1RMHP@1236|Gammaproteobacteria,1XSES@135623|Vibrionales	135623|Vibrionales	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
k141_182_109	575788.VS_2597	9.76e-63	199.0	COG1546@1|root,COG1546@2|Bacteria,1RH2Y@1224|Proteobacteria,1S5WH@1236|Gammaproteobacteria,1XXEF@135623|Vibrionales	135623|Vibrionales	S	Belongs to the CinA family	-	-	3.5.1.42	ko:K03743	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA
k141_182_111	1348635.BBJY01000002_gene3637	1.44e-180	509.0	COG0568@1|root,COG0568@2|Bacteria,1MUDI@1224|Proteobacteria,1RN8V@1236|Gammaproteobacteria,1XSUN@135623|Vibrionales	135623|Vibrionales	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	rpoS	-	-	ko:K03087	ko02026,ko05111,map02026,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
k141_182_112	675813.VIB_002017	9.39e-116	343.0	COG1388@1|root,COG4942@1|root,COG1388@2|Bacteria,COG4942@2|Bacteria,1RD24@1224|Proteobacteria,1RR11@1236|Gammaproteobacteria,1XSDC@135623|Vibrionales	135623|Vibrionales	M	COG0739 Membrane proteins related to metalloendopeptidases	nlpD	-	-	ko:K06194	-	-	-	-	ko00000	1.A.34.1.2	-	-	LysM,Peptidase_M23
k141_182_113	55601.VANGNB10_cI0438	3.02e-106	311.0	COG2518@1|root,COG2518@2|Bacteria,1MXQC@1224|Proteobacteria,1RMHZ@1236|Gammaproteobacteria,1XUP9@135623|Vibrionales	135623|Vibrionales	J	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	pcm	GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0030091,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
k141_182_114	945550.VISI1226_02080	2.56e-141	403.0	COG0496@1|root,COG0496@2|Bacteria,1MVHE@1224|Proteobacteria,1RN36@1236|Gammaproteobacteria,1XT84@135623|Vibrionales	135623|Vibrionales	S	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates	surE	-	3.1.3.5	ko:K03787	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	SurE
k141_182_115	674977.VMC_07990	2.33e-175	497.0	COG0585@1|root,COG0585@2|Bacteria,1MXHD@1224|Proteobacteria,1RPRF@1236|Gammaproteobacteria,1XTNP@135623|Vibrionales	135623|Vibrionales	J	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs	truD	GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0016070,GO:0016853,GO:0016866,GO:0034641,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360	5.4.99.27	ko:K06176	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruD
k141_2863_1	1128421.JAGA01000003_gene3022	7.93e-42	166.0	COG1306@1|root,COG1306@2|Bacteria,2NQXI@2323|unclassified Bacteria	2|Bacteria	S	Putative glycosyl hydrolase domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4015
k141_2545_1	675815.VOA_000473	7.87e-111	340.0	COG2838@1|root,COG2838@2|Bacteria,1MV6Q@1224|Proteobacteria,1RPG4@1236|Gammaproteobacteria,1XUW0@135623|Vibrionales	135623|Vibrionales	C	Isocitrate dehydrogenase	icd	-	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	IDH
k141_2545_2	672.VV93_v1c20360	3.03e-105	310.0	COG1187@1|root,COG1187@2|Bacteria,1R9VV@1224|Proteobacteria,1S1ZX@1236|Gammaproteobacteria,1XUNX@135623|Vibrionales	135623|Vibrionales	J	Belongs to the pseudouridine synthase RsuA family	rluE	GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	5.4.99.20	ko:K06181	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2
k141_1979_2	1267005.KB911266_gene1250	2.05e-80	260.0	COG0517@1|root,COG0517@2|Bacteria,1MXI6@1224|Proteobacteria,2TS6X@28211|Alphaproteobacteria,3N7U4@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	S	Putative transposase	-	-	-	-	-	-	-	-	-	-	-	-	Y2_Tnp,Zn_Tnp_IS91
k141_616_1	1121396.KB892916_gene80	4.7e-17	80.5	COG0811@1|root,COG0811@2|Bacteria,1QWME@1224|Proteobacteria,42S87@68525|delta/epsilon subdivisions,2X736@28221|Deltaproteobacteria,2MJX6@213118|Desulfobacterales	28221|Deltaproteobacteria	U	Protein of unknown function (DUF3450)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3450
k141_2864_2	1437608.BBIA_0857	1.69e-11	68.6	COG0577@1|root,COG0577@2|Bacteria,2GIRW@201174|Actinobacteria,4CZMQ@85004|Bifidobacteriales	201174|Actinobacteria	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
k141_339_1	596152.DesU5LDRAFT_3756	5.47e-158	459.0	COG4916@1|root,COG4916@2|Bacteria,1RIWC@1224|Proteobacteria,43CRJ@68525|delta/epsilon subdivisions,2WTIF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	TIR domain	-	-	-	-	-	-	-	-	-	-	-	-	SIR2_2,TIR_2
k141_339_2	930166.CD58_11525	2.22e-226	638.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,1RMBQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	belongs to the aldehyde dehydrogenase family	-	-	1.2.1.16,1.2.1.20,1.2.1.79	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	M00027	R00713,R00714,R02401	RC00080	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
k141_339_3	400668.Mmwyl1_3080	5.52e-205	573.0	COG0473@1|root,COG0473@2|Bacteria,1MUH4@1224|Proteobacteria,1RRPI@1236|Gammaproteobacteria,1XNNF@135619|Oceanospirillales	135619|Oceanospirillales	CE	Tartrate dehydrogenase	tdh	-	1.1.1.83,1.1.1.93,4.1.1.73	ko:K07246	ko00630,ko00650,map00630,map00650	-	R00215,R01751,R02545,R06180	RC00084,RC00105,RC00594	ko00000,ko00001,ko01000	-	-	-	Iso_dh
k141_339_4	1396141.BATP01000032_gene4306	6.99e-53	183.0	COG0823@1|root,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_339_5	572544.Ilyop_1638	2.01e-91	271.0	COG1695@1|root,COG1695@2|Bacteria,37CQK@32066|Fusobacteria	32066|Fusobacteria	K	PFAM transcriptional regulator PadR family protein	-	-	-	-	-	-	-	-	-	-	-	-	PadR,Vir_act_alpha_C
k141_339_6	572544.Ilyop_1639	7.26e-30	115.0	COG2223@1|root,COG2223@2|Bacteria	2|Bacteria	P	nitrite transmembrane transporter activity	-	-	-	ko:K08177	-	-	-	-	ko00000,ko02000	2.A.1.11	-	-	MFS_1,Nodulin-like
k141_339_7	1283284.AZUK01000002_gene2825	6.92e-67	214.0	COG2223@1|root,COG2223@2|Bacteria,1MWC7@1224|Proteobacteria,1RY1W@1236|Gammaproteobacteria,1Y5ET@135624|Aeromonadales	135624|Aeromonadales	P	Major Facilitator Superfamily	-	-	-	ko:K08177	-	-	-	-	ko00000,ko02000	2.A.1.11	-	-	MFS_1
k141_339_8	722419.PH505_fc00010	7.63e-78	254.0	COG3385@1|root,COG3385@2|Bacteria,1RBZF@1224|Proteobacteria,1S381@1236|Gammaproteobacteria,2Q49R@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
k141_339_9	1449050.JNLE01000003_gene1389	3.68e-44	155.0	COG2223@1|root,COG2223@2|Bacteria,1TPR9@1239|Firmicutes,2483N@186801|Clostridia,36FJK@31979|Clostridiaceae	186801|Clostridia	P	Major Facilitator	-	-	-	ko:K08177	-	-	-	-	ko00000,ko02000	2.A.1.11	-	-	MFS_1,Nodulin-like
k141_339_10	1449050.JNLE01000003_gene1390	2.67e-150	442.0	COG0446@1|root,COG1902@1|root,COG0446@2|Bacteria,COG1902@2|Bacteria,1TPM6@1239|Firmicutes,247V1@186801|Clostridia,36EGZ@31979|Clostridiaceae	186801|Clostridia	C	NADH flavin oxidoreductase NADH oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_FMN,Pyr_redox_2
k141_339_11	1283284.AZUK01000002_gene2824	7.23e-46	163.0	COG0446@1|root,COG1902@1|root,COG0446@2|Bacteria,COG1902@2|Bacteria,1MVE0@1224|Proteobacteria,1RNM8@1236|Gammaproteobacteria,1Y4C6@135624|Aeromonadales	135624|Aeromonadales	C	COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family	fadH	-	1.3.1.34	ko:K00219	-	-	-	-	ko00000,ko01000	-	-	-	Oxidored_FMN,Pyr_redox_2
k141_339_12	590409.Dd586_0018	4.91e-148	427.0	COG0657@1|root,COG0657@2|Bacteria,1R4AU@1224|Proteobacteria,1RQMN@1236|Gammaproteobacteria,2JDQ1@204037|Dickeya	1236|Gammaproteobacteria	I	PFAM Alpha beta hydrolase fold-3 domain protein	aes	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3,Peptidase_S9
k141_339_14	298386.PBPRB0216	9.23e-244	695.0	COG3284@1|root,COG3284@2|Bacteria,1NRG5@1224|Proteobacteria,1RQQD@1236|Gammaproteobacteria,1XVAT@135623|Vibrionales	135623|Vibrionales	K	PAS domain	-	-	-	ko:K05880	-	-	-	-	ko00000,ko03000	-	-	-	HTH_8,PAS,Sigma54_activat
k141_339_15	298386.PBPRB0219	2.3e-199	558.0	COG2376@1|root,COG2376@2|Bacteria,1MVSR@1224|Proteobacteria,1RNRQ@1236|Gammaproteobacteria,1XW62@135623|Vibrionales	135623|Vibrionales	G	dihydroxyacetone kinase	-	-	2.7.1.121	ko:K05878	ko00561,ko01100,map00561,map01100	-	R01012	RC00015,RC00017	ko00000,ko00001,ko01000	-	-	-	Dak1
k141_339_16	298386.PBPRB0218	4.6e-96	285.0	COG1461@1|root,COG1461@2|Bacteria,1MXIB@1224|Proteobacteria,1RPJ7@1236|Gammaproteobacteria,1XX2K@135623|Vibrionales	135623|Vibrionales	S	With DhaK and DhaM catalyzes the phosphorylation of dihydroxyacetone	-	-	2.7.1.121	ko:K05879	ko00561,ko01100,map00561,map01100	-	R01012	RC00015,RC00017	ko00000,ko00001,ko01000	-	-	-	Dak2
k141_339_17	298386.PBPRB0217	1.88e-299	851.0	COG1080@1|root,COG1925@1|root,COG3412@1|root,COG1080@2|Bacteria,COG1925@2|Bacteria,COG3412@2|Bacteria,1MUT8@1224|Proteobacteria,1RN6R@1236|Gammaproteobacteria,1XWKF@135623|Vibrionales	135623|Vibrionales	G	PTS system fructose IIA component	-	-	2.7.1.202,2.7.3.9	ko:K02768,ko:K08483,ko:K11183,ko:K11189	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	M00273	R03232	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.2.1,8.A.7	-	-	EIIA-man,PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C,PTS-HPr
k141_339_18	314292.VAS14_04018	2.48e-136	400.0	COG5438@1|root,COG5438@2|Bacteria,1MYCQ@1224|Proteobacteria,1S1SI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	YibE/F-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YibE_F
k141_339_19	314292.VAS14_04023	1.2e-199	568.0	COG1785@1|root,COG1785@2|Bacteria,1MXI2@1224|Proteobacteria,1RNG8@1236|Gammaproteobacteria,1XTK7@135623|Vibrionales	135623|Vibrionales	P	Belongs to the alkaline phosphatase family	-	-	3.1.3.1	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	M00126	R02135,R04620	RC00017	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	-	-	-	Alk_phosphatase
k141_2546_1	1121396.KB893105_gene1800	5.2e-55	192.0	COG0811@1|root,COG0811@2|Bacteria,1MX5J@1224|Proteobacteria,42NWR@68525|delta/epsilon subdivisions,2WK2E@28221|Deltaproteobacteria,2MN43@213118|Desulfobacterales	28221|Deltaproteobacteria	U	MotA/TolQ/ExbB proton channel family	-	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	DUF3450,MotA_ExbB
k141_340_2	1265505.ATUG01000002_gene1396	1.86e-09	60.5	2CI36@1|root,32S77@2|Bacteria,1N2YG@1224|Proteobacteria,42UEU@68525|delta/epsilon subdivisions,2WQZY@28221|Deltaproteobacteria,2MKF2@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Chemotaxis phosphatase CheX	-	-	-	-	-	-	-	-	-	-	-	-	CheX
k141_340_3	439235.Dalk_0655	1.02e-53	178.0	COG2201@1|root,COG2201@2|Bacteria,1MWCN@1224|Proteobacteria,42M27@68525|delta/epsilon subdivisions,2WJ2S@28221|Deltaproteobacteria,2MHVY@213118|Desulfobacterales	28221|Deltaproteobacteria	NT	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR	cheB	-	3.1.1.61,3.5.1.44	ko:K03412	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,Response_reg
k141_1285_1	675813.VIB_001078	1.4e-226	643.0	COG1757@1|root,COG1757@2|Bacteria,1MY5C@1224|Proteobacteria,1RP6I@1236|Gammaproteobacteria,1XSDA@135623|Vibrionales	135623|Vibrionales	C	COG1757 Na H antiporter	-	-	-	ko:K18218	-	M00667	-	-	ko00000,ko00002,ko01504,ko02000	-	-	-	Na_H_antiporter
k141_1285_2	870967.VIS19158_15354	1.15e-173	489.0	COG0040@1|root,COG0040@2|Bacteria,1MUCY@1224|Proteobacteria,1RNAX@1236|Gammaproteobacteria,1XTJ4@135623|Vibrionales	135623|Vibrionales	F	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity	hisG	GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.4.2.17	ko:K00765	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002,ko01000	-	-	-	HisG,HisG_C
k141_1285_3	672.VV93_v1c12640	1.05e-245	682.0	COG0141@1|root,COG0141@2|Bacteria,1MUUF@1224|Proteobacteria,1RMZD@1236|Gammaproteobacteria,1XTSW@135623|Vibrionales	135623|Vibrionales	E	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine	hisD	GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.23	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01158,R01163,R03012	RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000	-	-	-	Histidinol_dh
k141_1285_4	1219065.VPR01S_03_00070	1.53e-194	546.0	COG0079@1|root,COG0079@2|Bacteria,1MW7I@1224|Proteobacteria,1RP4T@1236|Gammaproteobacteria,1XTFK@135623|Vibrionales	135623|Vibrionales	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily	hisC	GO:0000105,GO:0003674,GO:0003824,GO:0004400,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
k141_1285_6	55601.VANGNB10_cI1071	8.04e-122	350.0	COG0118@1|root,COG0118@2|Bacteria,1MU4X@1224|Proteobacteria,1RRP3@1236|Gammaproteobacteria,1XUI3@135623|Vibrionales	135623|Vibrionales	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR	hisH	GO:0000105,GO:0000107,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	-	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
k141_1285_7	870967.VIS19158_15379	7.18e-153	432.0	COG0106@1|root,COG0106@2|Bacteria,1MW6S@1224|Proteobacteria,1RN3M@1236|Gammaproteobacteria,1XUYR@135623|Vibrionales	135623|Vibrionales	E	1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase	hisA	GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	5.3.1.16	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04640	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
k141_1285_8	1280001.BAOA01000027_gene4789	1.11e-162	457.0	COG0107@1|root,COG0107@2|Bacteria,1MUS0@1224|Proteobacteria,1RPJQ@1236|Gammaproteobacteria,1XT21@135623|Vibrionales	135623|Vibrionales	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit	hisF	GO:0000105,GO:0000107,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	-	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
k141_1285_9	55601.VANGNB10_cI1074	1.01e-117	340.0	COG0139@1|root,COG0140@1|root,COG0139@2|Bacteria,COG0140@2|Bacteria,1MW67@1224|Proteobacteria,1RMV4@1236|Gammaproteobacteria,1XT5G@135623|Vibrionales	135623|Vibrionales	E	Histidine biosynthesis bifunctional protein HisIE	hisI	GO:0000105,GO:0003674,GO:0003824,GO:0004635,GO:0004636,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016462,GO:0016787,GO:0016810,GO:0016814,GO:0016817,GO:0016818,GO:0018130,GO:0019238,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	3.5.4.19,3.6.1.31	ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04035,R04037	RC00002,RC01055	ko00000,ko00001,ko00002,ko01000	-	-	-	PRA-CH,PRA-PH
k141_1285_10	1219072.VHA01S_002_00310	1.22e-163	465.0	COG0463@1|root,COG0463@2|Bacteria,1MWE5@1224|Proteobacteria,1RPCE@1236|Gammaproteobacteria,1XSFK@135623|Vibrionales	135623|Vibrionales	M	COG0463 Glycosyltransferases involved in cell wall biogenesis	-	-	-	ko:K20534	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.2.1.9	GT2	-	Glycos_transf_2
k141_1285_11	1179773.BN6_41100	6.68e-08	55.8	COG2246@1|root,COG2246@2|Bacteria,2IIGF@201174|Actinobacteria,4E5UI@85010|Pseudonocardiales	201174|Actinobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	GtrA
k141_1285_12	1116375.VEJY3_08125	3.42e-141	419.0	28MGP@1|root,2ZATU@2|Bacteria,1QME8@1224|Proteobacteria,1T5MA@1236|Gammaproteobacteria,1Y3CB@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_1285_13	1031711.RSPO_c02599	2.59e-155	451.0	COG2230@1|root,COG2230@2|Bacteria,1MX3U@1224|Proteobacteria,2VIPR@28216|Betaproteobacteria,1K1R1@119060|Burkholderiaceae	28216|Betaproteobacteria	M	cyclopropane-fatty-acyl-phospholipid synthase	cfa2	-	2.1.1.79	ko:K00574	-	-	-	-	ko00000,ko01000	-	-	-	CMAS
k141_1285_14	675816.VIA_002886	3.21e-77	234.0	COG1451@1|root,COG1451@2|Bacteria,1RDJ9@1224|Proteobacteria,1S45M@1236|Gammaproteobacteria,1XTK3@135623|Vibrionales	135623|Vibrionales	S	Metal-dependent hydrolase	ygjP	-	-	ko:K07043	-	-	-	-	ko00000	-	-	-	DUF45
k141_1285_15	1348635.BBJY01000019_gene591	3.36e-119	356.0	COG3129@1|root,COG3129@2|Bacteria,1MUI4@1224|Proteobacteria,1RMVA@1236|Gammaproteobacteria,1XTU3@135623|Vibrionales	135623|Vibrionales	J	Specifically methylates the adenine in position 1618 of 23S rRNA	rlmF	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0008988,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0052907,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.181	ko:K06970	-	-	R07232	RC00003,RC00335	ko00000,ko01000,ko03009	-	-	-	Methyltransf_10
k141_1285_16	243277.VC_1140	2.42e-102	305.0	COG1187@1|root,COG1187@2|Bacteria,1R9VV@1224|Proteobacteria,1S1ZX@1236|Gammaproteobacteria,1XUNX@135623|Vibrionales	135623|Vibrionales	J	Belongs to the pseudouridine synthase RsuA family	rluE	GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	5.4.99.20	ko:K06181	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2
k141_1285_17	1219077.VAZ01S_016_00730	1.51e-146	437.0	COG2838@1|root,COG2838@2|Bacteria,1MV6Q@1224|Proteobacteria,1RPG4@1236|Gammaproteobacteria,1XUW0@135623|Vibrionales	135623|Vibrionales	C	Isocitrate dehydrogenase	icd	-	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	IDH
k141_2549_1	1121396.KB893105_gene1812	2.42e-43	140.0	COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,42V0K@68525|delta/epsilon subdivisions,2WR92@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	PFAM Cold-shock protein, DNA-binding	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
k141_3964_1	29495.EA26_00335	3.28e-122	353.0	COG0543@1|root,COG0543@2|Bacteria,1MV72@1224|Proteobacteria,1RPH5@1236|Gammaproteobacteria,1XVAC@135623|Vibrionales	135623|Vibrionales	C	COG0543 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases	fre	-	1.16.1.3,1.5.1.41	ko:K05368	ko00740,ko00860,ko01100,map00740,map00860,map01100	-	R00097,R05705	RC00126,RC00220	ko00000,ko00001,ko01000	-	-	-	FAD_binding_6,NAD_binding_1
k141_1286_1	1121396.KB893077_gene739	1.72e-94	287.0	COG0438@1|root,COG0662@1|root,COG0438@2|Bacteria,COG0662@2|Bacteria,1MWSZ@1224|Proteobacteria,42NYZ@68525|delta/epsilon subdivisions,2WK9U@28221|Deltaproteobacteria,2MMTM@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1,MannoseP_isomer
k141_1286_2	1121396.KB893077_gene740	6.5e-64	203.0	COG2152@1|root,COG2152@2|Bacteria,1MX8M@1224|Proteobacteria,42QDF@68525|delta/epsilon subdivisions,2WMG5@28221|Deltaproteobacteria,2MJJI@213118|Desulfobacterales	28221|Deltaproteobacteria	G	beta-1,4-mannooligosaccharide phosphorylase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_130
k141_2550_1	1255043.TVNIR_1463	3.5e-09	63.2	COG1332@1|root,COG3064@1|root,COG1332@2|Bacteria,COG3064@2|Bacteria,1REN1@1224|Proteobacteria	1224|Proteobacteria	L	TIGRFAM CRISPR-associated RAMP protein, Csm5 family	-	-	-	ko:K19140	-	-	-	-	ko00000,ko02048	-	-	-	RAMPs
k141_4674_1	177437.HRM2_21020	3.38e-73	234.0	COG0443@1|root,COG0443@2|Bacteria,1P7BK@1224|Proteobacteria,42PNW@68525|delta/epsilon subdivisions,2WKSX@28221|Deltaproteobacteria,2MHUK@213118|Desulfobacterales	28221|Deltaproteobacteria	O	PRTRC system protein D	-	-	-	ko:K18640	-	-	-	-	ko00000,ko04812	-	-	-	-
k141_4674_2	1304885.AUEY01000002_gene294	1.27e-136	404.0	COG2203@1|root,COG3437@1|root,COG2203@2|Bacteria,COG3437@2|Bacteria,1RGKE@1224|Proteobacteria,42QI9@68525|delta/epsilon subdivisions,2WIV3@28221|Deltaproteobacteria,2MI92@213118|Desulfobacterales	28221|Deltaproteobacteria	T	GAF domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HD,Lactamase_B_2
k141_4674_3	1265505.ATUG01000002_gene2647	2.56e-51	169.0	COG1871@1|root,COG1871@2|Bacteria,1RDDB@1224|Proteobacteria,42S9S@68525|delta/epsilon subdivisions,2WNSD@28221|Deltaproteobacteria,2MJX9@213118|Desulfobacterales	28221|Deltaproteobacteria	NT	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis	cheD2	-	3.5.1.44	ko:K03411	ko02030,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheD
k141_4674_4	269799.Gmet_2089	1.31e-19	82.8	2E8BS@1|root,332QF@2|Bacteria,1N9X2@1224|Proteobacteria,431DN@68525|delta/epsilon subdivisions,2WX5W@28221|Deltaproteobacteria,43VDY@69541|Desulfuromonadales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_4674_5	96561.Dole_2697	1.38e-55	179.0	COG0691@1|root,COG0691@2|Bacteria,1RDFP@1224|Proteobacteria,42SJ8@68525|delta/epsilon subdivisions,2WP5B@28221|Deltaproteobacteria,2MJHE@213118|Desulfobacterales	28221|Deltaproteobacteria	O	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene	smpB	-	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
k141_4674_6	933262.AXAM01000081_gene2257	2e-189	548.0	COG1080@1|root,COG1080@2|Bacteria,1MUT8@1224|Proteobacteria,42P77@68525|delta/epsilon subdivisions,2WK7E@28221|Deltaproteobacteria,2MIQB@213118|Desulfobacterales	28221|Deltaproteobacteria	G	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)	ptsI	-	2.7.3.9	ko:K08483	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	8.A.7	-	-	PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C
k141_3967_1	944547.ABLL_1725	1.09e-32	131.0	COG0715@1|root,COG0834@1|root,COG4191@1|root,COG0715@2|Bacteria,COG0834@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,43CE0@68525|delta/epsilon subdivisions,2YTBK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Bacterial periplasmic substrate-binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,NMT1,SBP_bac_3
k141_3260_1	1304885.AUEY01000039_gene1543	6.17e-50	171.0	COG0056@1|root,COG0056@2|Bacteria,1MUG7@1224|Proteobacteria,42MVX@68525|delta/epsilon subdivisions,2WIK7@28221|Deltaproteobacteria,2MIHR@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
k141_3260_2	96561.Dole_0600	1.07e-56	183.0	COG0712@1|root,COG0712@2|Bacteria,1MVRH@1224|Proteobacteria,42U68@68525|delta/epsilon subdivisions,2WQJS@28221|Deltaproteobacteria,2MJKI@213118|Desulfobacterales	28221|Deltaproteobacteria	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpH	-	-	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	OSCP
k141_3260_3	177437.HRM2_35210	6.03e-31	119.0	COG0711@1|root,COG0711@2|Bacteria,1N97K@1224|Proteobacteria,42VYP@68525|delta/epsilon subdivisions,2WR6T@28221|Deltaproteobacteria,2MK1E@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	atpF	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045263,GO:0045264,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
k141_2865_1	1121405.dsmv_3107	0.0	924.0	COG0466@1|root,COG0466@2|Bacteria,1MUV2@1224|Proteobacteria,42M9W@68525|delta/epsilon subdivisions,2WJ29@28221|Deltaproteobacteria,2MJ5T@213118|Desulfobacterales	28221|Deltaproteobacteria	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon-2	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
k141_2865_2	1232437.KL661965_gene3253	2.12e-09	57.4	COG1219@1|root,COG1219@2|Bacteria,1MVQK@1224|Proteobacteria,42MWJ@68525|delta/epsilon subdivisions,2WJ8Q@28221|Deltaproteobacteria,2MHKY@213118|Desulfobacterales	28221|Deltaproteobacteria	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
k141_1980_1	1121405.dsmv_0063	9.56e-132	399.0	COG0045@1|root,COG1042@1|root,COG0045@2|Bacteria,COG1042@2|Bacteria,1MW98@1224|Proteobacteria,42KZW@68525|delta/epsilon subdivisions,2WIQB@28221|Deltaproteobacteria,2MITU@213118|Desulfobacterales	28221|Deltaproteobacteria	C	CoA binding domain	-	-	6.2.1.13	ko:K01905,ko:K22224	ko00010,ko00620,ko00640,ko01100,ko01120,map00010,map00620,map00640,map01100,map01120	-	R00229,R00920	RC00004,RC00012,RC00014	ko00000,ko00001,ko01000,ko01004	-	-	-	ATP-grasp_5,Acetyltransf_3,CoA_binding_2,Succ_CoA_lig
k141_1980_2	76114.p2A341	1.76e-60	199.0	COG1024@1|root,COG1024@2|Bacteria,1MWF6@1224|Proteobacteria,2VJSH@28216|Betaproteobacteria,2KYRS@206389|Rhodocyclales	206389|Rhodocyclales	I	enoyl-CoA hydratase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
k141_1980_3	1123301.KB904188_gene512	4.08e-55	190.0	COG1207@1|root,COG1207@2|Bacteria,1TP88@1239|Firmicutes,4H9V5@91061|Bacilli	91061|Bacilli	M	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain	glmU	GO:0000270,GO:0000271,GO:0003674,GO:0003824,GO:0003977,GO:0005975,GO:0005976,GO:0006022,GO:0006023,GO:0006024,GO:0006629,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009252,GO:0009273,GO:0009987,GO:0016051,GO:0016740,GO:0016772,GO:0016779,GO:0030203,GO:0033692,GO:0034637,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0070569,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:1903509	2.3.1.157,2.7.7.23	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00362	R00416,R05332	RC00002,RC00004,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,Hexapep_2,NTP_transf_3,NTP_transferase
k141_4977_4	598467.BrE312_1463	2.09e-74	238.0	COG1129@1|root,COG1129@2|Bacteria,1MU22@1224|Proteobacteria,1RMCH@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	import. Responsible for energy coupling to the transport system	-	-	3.6.3.17	ko:K10441	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	ABC_tran
k141_4710_1	1224318.DT73_20970	1.18e-161	476.0	COG3002@1|root,COG3002@2|Bacteria,1MX5K@1224|Proteobacteria,1RQC2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Belongs to the UPF0753 family	-	-	-	ko:K09822	-	-	-	-	ko00000	-	-	-	DUF2309
k141_4710_2	1280001.BAOA01000007_gene4025	4.42e-27	108.0	COG0583@1|root,COG0583@2|Bacteria,1N663@1224|Proteobacteria,1RMFD@1236|Gammaproteobacteria,1XVT1@135623|Vibrionales	135623|Vibrionales	K	Bacterial regulatory helix-turn-helix protein, lysR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
k141_4978_1	1121448.DGI_4068	1.14e-51	172.0	COG0714@1|root,COG0714@2|Bacteria,1PHW4@1224|Proteobacteria,42QA8@68525|delta/epsilon subdivisions,2WJBW@28221|Deltaproteobacteria,2M8NS@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	PFAM ATPase associated with various cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	AAA_3,AAA_5
k141_4712_1	1265505.ATUG01000003_gene652	7.73e-54	177.0	COG0601@1|root,COG0601@2|Bacteria,1MU8Z@1224|Proteobacteria,42P18@68525|delta/epsilon subdivisions,2WKFV@28221|Deltaproteobacteria,2MIKS@213118|Desulfobacterales	28221|Deltaproteobacteria	EP	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
k141_4712_2	1265505.ATUG01000003_gene652	2.52e-37	134.0	COG0601@1|root,COG0601@2|Bacteria,1MU8Z@1224|Proteobacteria,42P18@68525|delta/epsilon subdivisions,2WKFV@28221|Deltaproteobacteria,2MIKS@213118|Desulfobacterales	28221|Deltaproteobacteria	EP	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
k141_2317_1	933262.AXAM01000001_gene334	3.42e-311	875.0	COG0653@1|root,COG0653@2|Bacteria,1MUJZ@1224|Proteobacteria,42MMV@68525|delta/epsilon subdivisions,2WIZ4@28221|Deltaproteobacteria,2MIJD@213118|Desulfobacterales	28221|Deltaproteobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	Helicase_C,SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
k141_2317_2	485915.Dret_1367	1.13e-35	124.0	COG2127@1|root,COG2127@2|Bacteria,1MZU8@1224|Proteobacteria,42TN3@68525|delta/epsilon subdivisions,2WQ23@28221|Deltaproteobacteria,2MCM5@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation	clpS	-	-	ko:K06891	-	-	-	-	ko00000	-	-	-	ClpS
k141_2317_3	1304885.AUEY01000059_gene2412	6.34e-06	47.0	COG0542@1|root,COG0542@2|Bacteria,1MV8B@1224|Proteobacteria,42M2T@68525|delta/epsilon subdivisions,2WJ2W@28221|Deltaproteobacteria,2MHMB@213118|Desulfobacterales	28221|Deltaproteobacteria	O	ATP-dependent Clp protease ATP-binding subunit ClpA	clpA	-	-	ko:K03694	-	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
k141_4713_1	1123274.KB899409_gene438	9.44e-29	115.0	COG5581@1|root,COG5581@2|Bacteria,2J6AM@203691|Spirochaetes	203691|Spirochaetes	M	Type IV pilus assembly	-	-	-	-	-	-	-	-	-	-	-	-	PilZ
k141_3991_1	672.VV93_v1c21590	6.13e-12	65.1	2ER47@1|root,33IPS@2|Bacteria,1NHAY@1224|Proteobacteria,1SH4T@1236|Gammaproteobacteria,1XX51@135623|Vibrionales	135623|Vibrionales	S	Protein of unknown function (DUF2802)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2802
k141_3991_2	945550.VISI1226_23112	2.09e-101	295.0	COG0835@1|root,COG0835@2|Bacteria,1RAH1@1224|Proteobacteria,1SYDF@1236|Gammaproteobacteria,1XSQC@135623|Vibrionales	135623|Vibrionales	NT	COG0835 Chemotaxis signal transduction protein	cheW	-	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
k141_3991_3	55601.VANGNB10_cI1872c	2.14e-99	303.0	COG0835@1|root,COG0835@2|Bacteria,1MYHY@1224|Proteobacteria,1S2TC@1236|Gammaproteobacteria,1XTG9@135623|Vibrionales	135623|Vibrionales	NT	Two component signalling adaptor domain	VP2226	-	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
k141_3991_4	55601.VANGNB10_cI1873c	2.45e-153	434.0	COG1192@1|root,COG1192@2|Bacteria,1MWSE@1224|Proteobacteria,1RQ3X@1236|Gammaproteobacteria,1XUJC@135623|Vibrionales	135623|Vibrionales	D	COG1192 ATPases involved in chromosome partitioning	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
k141_3991_5	243277.VC_2062	1.1e-202	569.0	COG2201@1|root,COG2201@2|Bacteria,1MWCN@1224|Proteobacteria,1RN67@1236|Gammaproteobacteria,1XU6C@135623|Vibrionales	135623|Vibrionales	NT	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR	cheB	GO:0003674,GO:0003824,GO:0006935,GO:0008150,GO:0008984,GO:0009605,GO:0016787,GO:0016788,GO:0040011,GO:0042221,GO:0042330,GO:0050896,GO:0051723,GO:0052689,GO:0140096	3.1.1.61,3.5.1.44	ko:K03412	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,Response_reg
k141_2318_1	933262.AXAM01000091_gene2607	3.21e-46	158.0	COG0811@1|root,COG0811@2|Bacteria,1MX60@1224|Proteobacteria,42S37@68525|delta/epsilon subdivisions,2WNDZ@28221|Deltaproteobacteria,2MJWJ@213118|Desulfobacterales	28221|Deltaproteobacteria	U	PFAM MotA TolQ ExbB proton channel	-	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
k141_891_1	1267535.KB906767_gene4127	3.3e-36	139.0	COG1476@1|root,COG1910@1|root,COG1476@2|Bacteria,COG1910@2|Bacteria,3Y5P8@57723|Acidobacteria	57723|Acidobacteria	K	Helix-turn-helix domain	-	-	-	ko:K07729	-	-	-	-	ko00000,ko03000	-	-	-	HTH_3
k141_4980_1	1304885.AUEY01000017_gene3714	1.76e-116	369.0	COG3829@1|root,COG3829@2|Bacteria,1N4M6@1224|Proteobacteria,42M38@68525|delta/epsilon subdivisions,2WIR0@28221|Deltaproteobacteria,2MJ85@213118|Desulfobacterales	28221|Deltaproteobacteria	T	sigma-54 factor interaction domain-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,PAS_3,PAS_4,PAS_9,Sigma54_activat
k141_2889_1	203275.BFO_0133	1.11e-186	546.0	COG1882@1|root,COG1882@2|Bacteria,4NDWW@976|Bacteroidetes,2FMC2@200643|Bacteroidia,22WNW@171551|Porphyromonadaceae	976|Bacteroidetes	C	Pyruvate formate lyase-like	-	-	2.3.1.54,4.1.1.83	ko:K00656,ko:K18427	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	-	R00212,R06987	RC00004,RC01181,RC02742,RC02833	ko00000,ko00001,ko01000	-	-	-	Gly_radical,PFL-like
k141_2392_3	1127696.HMPREF9134_00331	4.6e-84	267.0	COG1132@1|root,COG1132@2|Bacteria,4NG32@976|Bacteroidetes,2FNJK@200643|Bacteroidia,22W1U@171551|Porphyromonadaceae	976|Bacteroidetes	V	ABC transporter, ATP-binding protein	lmrA	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
k141_4784_2	443143.GM18_4295	3.36e-43	142.0	COG3952@1|root,COG3952@2|Bacteria,1MZ60@1224|Proteobacteria,431TK@68525|delta/epsilon subdivisions,2WW9K@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM lipid A biosynthesis domain protein	-	-	-	-	-	-	-	-	-	-	-	-	LAB_N
k141_4784_3	351348.Maqu_0284	2.43e-66	213.0	COG0463@1|root,COG0463@2|Bacteria,1MW2G@1224|Proteobacteria,1S22P@1236|Gammaproteobacteria,465K4@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	COG0463 Glycosyltransferases involved in cell wall biogenesis	dpm1	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
k141_79_2	706587.Desti_0497	3.19e-144	425.0	COG3385@1|root,COG3385@2|Bacteria,1MVRM@1224|Proteobacteria,42U5W@68525|delta/epsilon subdivisions,2WQUQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	PFAM Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,Nterm_IS4
k141_1752_2	96561.Dole_0449	4.46e-22	95.1	2CDHP@1|root,32RXU@2|Bacteria,1N1BP@1224|Proteobacteria,42TPT@68525|delta/epsilon subdivisions,2WQE6@28221|Deltaproteobacteria,2MJZK@213118|Desulfobacterales	28221|Deltaproteobacteria	S	RsbT co-antagonist protein rsbRD N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RsbRD_N
k141_1752_3	1304885.AUEY01000002_gene401	2.46e-155	444.0	COG2181@1|root,COG2181@2|Bacteria,1R48S@1224|Proteobacteria,42MZU@68525|delta/epsilon subdivisions,2WKKU@28221|Deltaproteobacteria,2MI6J@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM Nitrate reductase gamma subunit	dsrM	-	1.7.5.1	ko:K00374	ko00910,ko01120,ko02020,map00910,map01120,map02020	M00529,M00530	R00798,R01106,R09497	RC02812	ko00000,ko00001,ko00002,ko01000	5.A.3.1	-	-	Nitrate_red_gam
k141_1752_4	1304885.AUEY01000002_gene402	0.0	964.0	COG0247@1|root,COG0247@2|Bacteria,1NZIG@1224|Proteobacteria,42M60@68525|delta/epsilon subdivisions,2WITJ@28221|Deltaproteobacteria,2MHXY@213118|Desulfobacterales	28221|Deltaproteobacteria	C	4Fe-4S dicluster domain	dsrK	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_8
k141_1752_5	933262.AXAM01000094_gene2191	6.83e-57	180.0	arCOG10385@1|root,32SEM@2|Bacteria,1N1IG@1224|Proteobacteria,42TMW@68525|delta/epsilon subdivisions,2WQBW@28221|Deltaproteobacteria,2MK19@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	dsrJ	-	-	-	-	-	-	-	-	-	-	-	-
k141_5117_1	1026882.MAMP_01264	1.91e-36	133.0	COG3550@1|root,COG3550@2|Bacteria,1PD1S@1224|Proteobacteria,1RXIE@1236|Gammaproteobacteria,463CF@72273|Thiotrichales	72273|Thiotrichales	S	Pfam:HipA_N	-	-	-	-	-	-	-	-	-	-	-	-	Couple_hipA,HipA_C
k141_5117_2	561231.Pecwa_0549	1.88e-52	166.0	COG1396@1|root,COG1396@2|Bacteria,1QV8H@1224|Proteobacteria,1S6DU@1236|Gammaproteobacteria,1MSKS@122277|Pectobacterium	1236|Gammaproteobacteria	K	Cro/C1-type HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
k141_5117_3	55601.VANGNB10_cI2597c	0.0	1040.0	COG0514@1|root,COG0514@2|Bacteria,1MVGG@1224|Proteobacteria,1RMPG@1236|Gammaproteobacteria,1XU5H@135623|Vibrionales	135623|Vibrionales	L	DNA helicase	recQ	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,HRDC,Helicase_C,RQC,RecQ_Zn_bind
k141_5117_4	1219065.VPR01S_30_00120	3.08e-141	407.0	COG2962@1|root,COG2962@2|Bacteria,1MX5G@1224|Proteobacteria,1RMAC@1236|Gammaproteobacteria,1XSTP@135623|Vibrionales	135623|Vibrionales	S	EamA-like transporter family	rarD	-	-	ko:K05786	-	-	-	-	ko00000,ko02000	2.A.7.7	-	-	EamA
k141_5117_5	1219076.N646_2108	0.0	1306.0	COG0210@1|root,COG0210@2|Bacteria,1MU0G@1224|Proteobacteria,1RNJI@1236|Gammaproteobacteria,1XUIR@135623|Vibrionales	135623|Vibrionales	L	COG0210 Superfamily I DNA and RNA helicases	uvrD	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
k141_3429_1	1238450.VIBNISOn1_560092	9.78e-193	551.0	COG0147@1|root,COG0147@2|Bacteria,1MVBJ@1224|Proteobacteria,1RMSE@1236|Gammaproteobacteria,1XTES@135623|Vibrionales	135623|Vibrionales	EH	COG0147 Anthranilate para-aminobenzoate synthases component I	pabB	-	2.6.1.85	ko:K01665	ko00790,map00790	-	R01716	RC00010,RC01418	ko00000,ko00001,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
k141_3429_2	672.VV93_v1c18470	1.28e-64	205.0	COG0494@1|root,COG0494@2|Bacteria,1RD2C@1224|Proteobacteria,1SA4Q@1236|Gammaproteobacteria,1XWY8@135623|Vibrionales	135623|Vibrionales	L	COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes	nudL	-	-	-	-	-	-	-	-	-	-	-	NUDIX
k141_3429_3	211586.SO_2327	2.63e-104	314.0	COG2201@1|root,COG2201@2|Bacteria,1MWCN@1224|Proteobacteria,1RN67@1236|Gammaproteobacteria,2QAPX@267890|Shewanellaceae	1236|Gammaproteobacteria	NT	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR	-	-	3.1.1.61,3.5.1.44	ko:K03412	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,Response_reg
k141_5118_1	1265505.ATUG01000003_gene419	1.38e-27	105.0	COG1186@1|root,COG1186@2|Bacteria,1NBAD@1224|Proteobacteria,42UTT@68525|delta/epsilon subdivisions,2WQZK@28221|Deltaproteobacteria,2MKEQ@213118|Desulfobacterales	28221|Deltaproteobacteria	J	RF-1 domain	-	-	-	-	-	-	-	-	-	-	-	-	RF-1
k141_3092_1	657322.FPR_13990	5.15e-158	463.0	COG3344@1|root,COG3344@2|Bacteria,1TP9A@1239|Firmicutes,248K6@186801|Clostridia,3WGKZ@541000|Ruminococcaceae	186801|Clostridia	L	Group II intron, maturase-specific domain	-	-	2.7.7.49	ko:K00986	-	-	-	-	ko00000,ko01000	-	-	-	GIIM,HNH,RVT_1,RVT_N
k141_4786_1	177437.HRM2_47180	2.6e-75	256.0	COG0210@1|root,COG0514@1|root,COG0210@2|Bacteria,COG0514@2|Bacteria,1MVGG@1224|Proteobacteria,42MV3@68525|delta/epsilon subdivisions,2WJZB@28221|Deltaproteobacteria,2MHKM@213118|Desulfobacterales	28221|Deltaproteobacteria	L	TIGRFAM ATP-dependent DNA helicase, RecQ	-	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,HRDC,HTH_40,Helicase_C,RQC,RecQ_Zn_bind,UvrD-helicase,UvrD_C
k141_3430_1	526222.Desal_0450	1.89e-44	160.0	COG2207@1|root,COG2207@2|Bacteria,1R5XY@1224|Proteobacteria,42V7F@68525|delta/epsilon subdivisions,2WR1R@28221|Deltaproteobacteria,2MFXZ@213115|Desulfovibrionales	28221|Deltaproteobacteria	K	PFAM helix-turn-helix- domain containing protein AraC type	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
k141_4787_1	1121396.KB893103_gene1771	1.68e-51	185.0	COG1033@1|root,COG1033@2|Bacteria,1MUE1@1224|Proteobacteria,42ME2@68525|delta/epsilon subdivisions,2WJRI@28221|Deltaproteobacteria,2MMR2@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Sterol-sensing domain of SREBP cleavage-activation	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	GGDEF,LolA_like,MMPL,cNMP_binding
k141_4448_1	491952.Mar181_2497	1.08e-18	85.9	COG3501@1|root,COG3501@2|Bacteria,1MU7Q@1224|Proteobacteria,1RMZS@1236|Gammaproteobacteria,1XIYM@135619|Oceanospirillales	135619|Oceanospirillales	M	Rhs element Vgr protein	-	-	-	ko:K11904	ko03070,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	Phage_GPD
k141_4448_2	55601.VANGNB10_cII0083	0.0	1625.0	COG3523@1|root,COG3523@2|Bacteria,1MV3D@1224|Proteobacteria,1RPQ2@1236|Gammaproteobacteria,1XSAX@135623|Vibrionales	135623|Vibrionales	S	protein conserved in bacteria	-	-	-	ko:K11891	ko02025,ko03070,map02025,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	IcmF-related,IcmF_C,ImcF-related_N
k141_4448_3	55601.VANGNB10_cII0082	7.1e-155	455.0	COG3515@1|root,COG3515@2|Bacteria,1MWDQ@1224|Proteobacteria,1RQXI@1236|Gammaproteobacteria,1XW10@135623|Vibrionales	135623|Vibrionales	S	protein conserved in bacteria	-	-	-	ko:K11910	-	M00334	-	-	ko00000,ko00002,ko02044	3.A.23.1	-	-	ImpA_N,T6SS_VasJ
k141_4448_4	55601.VANGNB10_cII0081	1.9e-55	183.0	2C9Y5@1|root,32RR9@2|Bacteria,1N3SX@1224|Proteobacteria,1SBDD@1236|Gammaproteobacteria,1XUFZ@135623|Vibrionales	135623|Vibrionales	S	Type VI secretion system VasI, EvfG, VC_A0118	-	-	-	ko:K11909	-	-	-	-	ko00000,ko02044	3.A.23.1	-	-	VasI
k141_4448_5	55601.VANGNB10_cII0080	9.6e-239	672.0	COG3829@1|root,COG3829@2|Bacteria,1MY61@1224|Proteobacteria,1RQWE@1236|Gammaproteobacteria,1XTZZ@135623|Vibrionales	135623|Vibrionales	K	Transcriptional regulator	-	-	-	ko:K11908	-	-	-	-	ko00000,ko03000	-	-	-	HTH_8,Sigma54_activat
k141_81_1	1441629.PCH70_31300	7.94e-16	85.9	2AXBE@1|root,32SE7@2|Bacteria,1N2SV@1224|Proteobacteria,1SBH2@1236|Gammaproteobacteria,1Z8EC@136849|Pseudomonas syringae group	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_5119_2	1163389.OOM_1113	2.78e-13	77.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,1RPCU@1236|Gammaproteobacteria,45ZXG@72273|Thiotrichales	72273|Thiotrichales	S	ABC transporter	-	-	-	ko:K15738	-	-	-	-	ko00000,ko02000	3.A.1.120.6	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
k141_5119_3	1121878.AUGL01000013_gene2899	4.73e-126	368.0	COG0609@1|root,COG0609@2|Bacteria,1MV9W@1224|Proteobacteria,1RMST@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily	-	-	-	-	-	-	-	-	-	-	-	-	FecCD
k141_1397_1	1348635.BBJY01000006_gene309	6.55e-48	164.0	COG0446@1|root,COG0446@2|Bacteria,1NR3M@1224|Proteobacteria,1T1WT@1236|Gammaproteobacteria,1XSS8@135623|Vibrionales	135623|Vibrionales	P	NAD(FAD)-dependent dehydrogenases	cdr	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Pyr_redox_dim,Rhodanese
k141_1397_2	243277.VC_A0643	9.54e-30	107.0	COG0607@1|root,32YCZ@2|Bacteria,1N6NN@1224|Proteobacteria,1SCRA@1236|Gammaproteobacteria,1XYYX@135623|Vibrionales	135623|Vibrionales	P	Protein of unknown function (DUF2892)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2892
k141_1397_3	55601.VANGNB10_cII0609c	4.86e-39	132.0	COG0640@1|root,COG0640@2|Bacteria,1N72Q@1224|Proteobacteria,1SCH5@1236|Gammaproteobacteria,1XYDG@135623|Vibrionales	135623|Vibrionales	K	Transcriptional regulator ArsR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
k141_1397_4	998088.B565_2751	2.13e-33	121.0	COG2391@1|root,COG2391@2|Bacteria,1MZ3A@1224|Proteobacteria,1S95T@1236|Gammaproteobacteria,1Y4T6@135624|Aeromonadales	135624|Aeromonadales	S	Sulphur transport	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
k141_1397_5	29495.EA26_11300	6.02e-55	176.0	COG2391@1|root,COG2391@2|Bacteria,1MZC0@1224|Proteobacteria,1S8UB@1236|Gammaproteobacteria,1XXV5@135623|Vibrionales	135623|Vibrionales	S	Transporter Component	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
k141_1397_6	345073.VC395_A0673	1.33e-109	329.0	COG0845@1|root,COG0845@2|Bacteria,1NQZ0@1224|Proteobacteria,1RR67@1236|Gammaproteobacteria,1XWM1@135623|Vibrionales	135623|Vibrionales	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
k141_1397_7	1348635.BBJY01000006_gene316	0.0	1556.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,1XV2Y@135623|Vibrionales	135623|Vibrionales	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k141_1397_8	1136163.M565_ctg5P0678	1.74e-71	229.0	COG0708@1|root,COG0708@2|Bacteria,1RBRF@1224|Proteobacteria,1S2T0@1236|Gammaproteobacteria,1XVH6@135623|Vibrionales	135623|Vibrionales	L	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
k141_1397_10	527002.yaldo0001_39170	2.87e-85	253.0	COG0602@1|root,COG0602@2|Bacteria,1RA7S@1224|Proteobacteria,1S20X@1236|Gammaproteobacteria,41EXW@629|Yersinia	1236|Gammaproteobacteria	O	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine	nrdG	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008998,GO:0009058,GO:0009117,GO:0009165,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0015949,GO:0016491,GO:0016725,GO:0016728,GO:0018130,GO:0019438,GO:0019637,GO:0019692,GO:0031250,GO:0032991,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046385,GO:0046483,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901576	1.97.1.4	ko:K04068	-	-	R04710	-	ko00000,ko01000	-	-	iE2348C_1286.E2348C_4563	Fer4_12
k141_1397_11	945550.VISI1226_16053	4.79e-51	171.0	COG4067@1|root,COG4067@2|Bacteria,1N7Y2@1224|Proteobacteria,1SBQN@1236|Gammaproteobacteria,1XUTD@135623|Vibrionales	135623|Vibrionales	O	protein conserved in archaea	-	-	-	-	-	-	-	-	-	-	-	-	Zn_protease
k141_1397_12	1348635.BBJY01000006_gene324	1.02e-288	803.0	COG1299@1|root,COG1445@1|root,COG1299@2|Bacteria,COG1445@2|Bacteria,1MXFN@1224|Proteobacteria,1RMZC@1236|Gammaproteobacteria,1XSC5@135623|Vibrionales	135623|Vibrionales	G	COG1445 Phosphotransferase system fructose-specific component IIB	fruA	-	2.7.1.202	ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	M00273	R03232	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.2.1	-	-	PTS_EIIC,PTS_IIB
k141_1397_13	55601.VANGNB10_cII0264c	1.14e-171	485.0	COG1105@1|root,COG1105@2|Bacteria,1MVNW@1224|Proteobacteria,1RP6K@1236|Gammaproteobacteria,1XSVH@135623|Vibrionales	135623|Vibrionales	H	belongs to the carbohydrate kinase PfkB family	fruK	-	2.7.1.56	ko:K00882	ko00051,map00051	-	R02071	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
k141_1397_14	1348635.BBJY01000006_gene326	9.36e-178	506.0	COG1925@1|root,COG4668@1|root,COG1925@2|Bacteria,COG4668@2|Bacteria,1MVP6@1224|Proteobacteria,1RQP4@1236|Gammaproteobacteria,1XSJ1@135623|Vibrionales	135623|Vibrionales	G	COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain	fruB	-	2.7.1.202	ko:K02768,ko:K11183	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	M00273	R03232	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.2.1	-	-	PTS-HPr,PTS_EIIA_2
k141_2395_1	199310.c0764	1.45e-90	277.0	COG1995@1|root,COG1995@2|Bacteria,1MX5W@1224|Proteobacteria,1RNZV@1236|Gammaproteobacteria,3XQIP@561|Escherichia	1236|Gammaproteobacteria	C	Pyridoxal phosphate biosynthetic protein PdxA	pdxA2	-	1.1.1.408,1.1.1.409	ko:K22024	-	-	-	-	ko00000,ko01000	-	-	-	PdxA
k141_2395_2	1524467.IV04_00065	1.82e-85	273.0	COG3395@1|root,COG3395@2|Bacteria,1MW4G@1224|Proteobacteria,1RYGE@1236|Gammaproteobacteria,401KR@613|Serratia	1236|Gammaproteobacteria	S	Putative nucleotide-binding of sugar-metabolising enzyme	ygbK	-	2.7.1.219,2.7.1.220	ko:K22129	-	-	-	-	ko00000,ko01000	-	-	-	DUF1357_C,DUF1537
k141_3093_1	1125863.JAFN01000001_gene2021	3.95e-137	409.0	COG4974@1|root,COG4974@2|Bacteria,1NY1A@1224|Proteobacteria,42NX3@68525|delta/epsilon subdivisions,2WME4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	High confidence in function and specificity	-	-	-	ko:K07484	-	-	-	-	ko00000	-	-	-	DDE_Tnp_IS66,DDE_Tnp_IS66_C,LZ_Tnp_IS66,zf-IS66
k141_3434_1	331678.Cphamn1_0259	6.59e-40	152.0	COG0500@1|root,COG0535@1|root,COG0535@2|Bacteria,COG2226@2|Bacteria,1FEMS@1090|Chlorobi	1090|Chlorobi	H	Radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31,Radical_SAM
k141_387_1	1151292.QEW_1626	1.37e-96	318.0	COG1196@1|root,COG1196@2|Bacteria,1TPJV@1239|Firmicutes,249F4@186801|Clostridia,25QTR@186804|Peptostreptococcaceae	186801|Clostridia	D	Required for chromosome condensation and partitioning	smc	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
k141_387_2	445973.CLOBAR_02210	1.99e-150	441.0	COG0552@1|root,COG0552@2|Bacteria,1TPRI@1239|Firmicutes,247JD@186801|Clostridia,25R1C@186804|Peptostreptococcaceae	186801|Clostridia	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)	ftsY	-	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
k141_387_3	1301100.HG529233_gene7433	3.77e-36	127.0	COG2739@1|root,COG2739@2|Bacteria,1VEGP@1239|Firmicutes,24QNM@186801|Clostridia,36MJ0@31979|Clostridiaceae	186801|Clostridia	S	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein	-	-	-	ko:K09787	-	-	-	-	ko00000	-	-	-	UPF0122
k141_387_4	1121324.CLIT_23c04230	3.41e-232	649.0	COG0541@1|root,COG0541@2|Bacteria,1TP06@1239|Firmicutes,248EU@186801|Clostridia,25QUD@186804|Peptostreptococcaceae	186801|Clostridia	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY	ffh	-	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
k141_387_5	500633.CLOHIR_01175	1.2e-39	132.0	COG0228@1|root,COG0228@2|Bacteria,1VA0X@1239|Firmicutes,24MND@186801|Clostridia,25RNI@186804|Peptostreptococcaceae	186801|Clostridia	J	Belongs to the bacterial ribosomal protein bS16 family	rpsP	-	-	ko:K02959	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S16
k141_387_6	1286171.EAL2_c12320	3.78e-33	115.0	COG1837@1|root,COG1837@2|Bacteria,1VEG7@1239|Firmicutes,24QKN@186801|Clostridia,25X88@186806|Eubacteriaceae	186801|Clostridia	S	Belongs to the UPF0109 family	ylqC	-	-	ko:K06960	-	-	-	-	ko00000	-	-	-	KH_4
k141_387_7	1347392.CCEZ01000043_gene296	2.18e-39	138.0	COG0806@1|root,COG0806@2|Bacteria,1V6HD@1239|Firmicutes,24I1G@186801|Clostridia,36IPC@31979|Clostridiaceae	186801|Clostridia	J	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes	rimM	-	-	ko:K02860	-	-	-	-	ko00000,ko03009	-	-	-	PRC,RimM
k141_387_8	1408422.JHYF01000001_gene2955	7.94e-94	282.0	COG0336@1|root,COG0336@2|Bacteria,1TPBV@1239|Firmicutes,247JF@186801|Clostridia,36EJ7@31979|Clostridiaceae	186801|Clostridia	J	Belongs to the RNA methyltransferase TrmD family	trmD	-	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	tRNA_m1G_MT
k141_387_9	1511.CLOST_1575	3.48e-58	182.0	COG0335@1|root,COG0335@2|Bacteria,1V6FT@1239|Firmicutes,24J83@186801|Clostridia,25RJR@186804|Peptostreptococcaceae	186801|Clostridia	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	rplS	-	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
k141_387_10	1408422.JHYF01000001_gene2957	1.4e-124	365.0	COG1161@1|root,COG1161@2|Bacteria,1TQGK@1239|Firmicutes,2490H@186801|Clostridia,36DQN@31979|Clostridiaceae	186801|Clostridia	S	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity	ylqF	-	-	ko:K14540	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1
k141_387_11	926692.AZYG01000059_gene113	1.46e-80	250.0	COG0164@1|root,COG0164@2|Bacteria,1V1D6@1239|Firmicutes,248IT@186801|Clostridia,3WAMH@53433|Halanaerobiales	186801|Clostridia	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhB	-	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
k141_387_13	755731.Clo1100_1808	8.07e-17	76.6	COG2257@1|root,COG2257@2|Bacteria,1VF4R@1239|Firmicutes,24QSW@186801|Clostridia,36NNP@31979|Clostridiaceae	186801|Clostridia	N	cytoplasmic domain of flagellar protein FhlB	flhB1	-	-	ko:K04061	-	-	-	-	ko00000,ko02044	-	-	-	Bac_export_2
k141_387_14	511680.BUTYVIB_00036	2.31e-18	81.3	COG0792@1|root,COG0792@2|Bacteria,1VFHQ@1239|Firmicutes,24QNK@186801|Clostridia,4BZWV@830|Butyrivibrio	186801|Clostridia	L	Uncharacterised protein family UPF0102	-	-	-	ko:K07460	-	-	-	-	ko00000	-	-	-	UPF0102
k141_387_15	1391646.AVSU01000050_gene1742	9.9e-197	564.0	COG0606@1|root,COG0606@2|Bacteria,1TPPB@1239|Firmicutes,248T8@186801|Clostridia,25QJ8@186804|Peptostreptococcaceae	186801|Clostridia	O	Mg chelatase-like protein	comM	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
k141_387_16	1415775.U729_391	1.68e-86	263.0	COG1760@1|root,COG1760@2|Bacteria,1U8TZ@1239|Firmicutes,24AEE@186801|Clostridia,36EDV@31979|Clostridiaceae	186801|Clostridia	E	L-serine dehydratase, iron-sulfur-dependent, beta subunit	sdaAB	-	4.3.1.17	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	-	R00220,R00590	RC00331,RC02600	ko00000,ko00001,ko01000	-	-	-	ACT,SDH_beta
k141_387_17	536232.CLM_1370	3.54e-129	376.0	COG1760@1|root,COG1760@2|Bacteria,1TP79@1239|Firmicutes,2480J@186801|Clostridia,36DCQ@31979|Clostridiaceae	186801|Clostridia	E	L-serine dehydratase, iron-sulfur-dependent, alpha subunit	sdaAA	-	4.3.1.17	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	-	R00220,R00590	RC00331,RC02600	ko00000,ko00001,ko01000	-	-	-	SDH_alpha
k141_387_18	536232.CLM_1396	2.38e-167	477.0	COG1299@1|root,COG1299@2|Bacteria,1UHP0@1239|Firmicutes,25EQ6@186801|Clostridia,36UR6@31979|Clostridiaceae	186801|Clostridia	G	Phosphotransferase system, EIIC	-	-	-	-	-	-	-	-	-	-	-	-	PTS_EIIC_2
k141_3095_2	439481.Aboo_1102	1.03e-19	83.6	COG0011@1|root,arCOG04373@2157|Archaea,2Y6H3@28890|Euryarchaeota,3F3EY@33867|unclassified Euryarchaeota	28890|Euryarchaeota	S	Thiamine-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Thiamine_BP
k141_1398_2	945543.VIBR0546_10769	2e-75	254.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1R81Y@1224|Proteobacteria,1RYQ2@1236|Gammaproteobacteria,1XUTT@135623|Vibrionales	135623|Vibrionales	T	COG0642 Signal transduction histidine kinase	luxN	-	2.7.13.3	ko:K15850	ko02020,ko02024,map02020,map02024	-	-	-	ko00000,ko00001,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,Response_reg
k141_1399_1	7029.ACYPI003238-PA	1.24e-23	99.8	COG3940@1|root,2R8XS@2759|Eukaryota,39RII@33154|Opisthokonta,3CACQ@33208|Metazoa,3DRI8@33213|Bilateria,427PE@6656|Arthropoda,3SQPD@50557|Insecta	33208|Metazoa	G	Glycosyl hydrolases family 43	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_43
k141_1399_2	243277.VC_A0486	1.04e-25	98.2	COG4453@1|root,COG4453@2|Bacteria,1N0BK@1224|Proteobacteria,1S8UN@1236|Gammaproteobacteria,1XYE0@135623|Vibrionales	135623|Vibrionales	S	Protein of unknown function (DUF1778)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1778
k141_392_1	933262.AXAM01000011_gene1789	8.98e-83	263.0	COG1672@1|root,COG1672@2|Bacteria,1N4VD@1224|Proteobacteria,42Y71@68525|delta/epsilon subdivisions,2WTK1@28221|Deltaproteobacteria,2MMHF@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Predicted AAA-ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA-ATPase_like,PDDEXK_9
k141_729_1	1234364.AMSF01000040_gene36	4.17e-18	86.3	COG0834@1|root,COG0834@2|Bacteria,1RD01@1224|Proteobacteria,1S43D@1236|Gammaproteobacteria,1XAFS@135614|Xanthomonadales	135614|Xanthomonadales	ET	ABC-type amino acid transport signal transduction systems periplasmic component domain	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_729_2	1122207.MUS1_02185	4.41e-93	276.0	COG0500@1|root,COG0500@2|Bacteria,1RDHE@1224|Proteobacteria,1S3U0@1236|Gammaproteobacteria,1XJY7@135619|Oceanospirillales	135619|Oceanospirillales	Q	Protein of unknown function (DUF938)	-	-	-	-	-	-	-	-	-	-	-	-	DUF938
k141_729_3	675817.VDA_000866	6.81e-109	320.0	COG3700@1|root,COG3700@2|Bacteria,1PRRA@1224|Proteobacteria,1RP0N@1236|Gammaproteobacteria,1XWUS@135623|Vibrionales	135623|Vibrionales	S	COG3700 Acid phosphatase (class B)	aphA	-	3.1.3.2	ko:K03788	ko00740,ko01100,map00740,map01100	-	R00548	RC00017	ko00000,ko00001,ko01000	-	-	-	Acid_phosphat_B
k141_729_4	1535422.ND16A_1446	2.5e-115	346.0	COG1835@1|root,COG1835@2|Bacteria,1RHQR@1224|Proteobacteria,1S8IU@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
k141_729_5	1120970.AUBZ01000008_gene2448	3.24e-58	190.0	COG0500@1|root,COG2226@2|Bacteria,1N0SX@1224|Proteobacteria	1224|Proteobacteria	Q	PFAM Methyltransferase type	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25,Methyltransf_31
k141_729_6	760154.Sulba_1998	9.39e-48	166.0	2AFRW@1|root,315TV@2|Bacteria,1PW73@1224|Proteobacteria,42ZYA@68525|delta/epsilon subdivisions,2YRUR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_729_7	1348635.BBJY01000002_gene3404	5.08e-106	307.0	2B0NW@1|root,31T0N@2|Bacteria,1QJDP@1224|Proteobacteria,1THCU@1236|Gammaproteobacteria,1XU2I@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_729_8	870967.VIS19158_23025	5.88e-97	296.0	COG2885@1|root,COG3637@1|root,COG2885@2|Bacteria,COG3637@2|Bacteria,1N6EM@1224|Proteobacteria,1SBXG@1236|Gammaproteobacteria,1XU00@135623|Vibrionales	135623|Vibrionales	M	Belongs to the ompA family	-	-	-	ko:K03286	-	-	-	-	ko00000,ko02000	1.B.6	-	-	OmpA,OmpA_membrane
k141_729_9	1348635.BBJY01000002_gene3405	4.6e-85	264.0	COG0008@1|root,COG0008@2|Bacteria,1MUCR@1224|Proteobacteria,1RN3R@1236|Gammaproteobacteria,1XTNZ@135623|Vibrionales	135623|Vibrionales	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
k141_3097_1	525897.Dbac_1915	7.59e-95	308.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MQ0@68525|delta/epsilon subdivisions,2WJ2A@28221|Deltaproteobacteria,2MG2S@213115|Desulfovibrionales	28221|Deltaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k141_4471_2	1205908.AKXW01000108_gene1229	1.69e-215	606.0	COG0534@1|root,COG0534@2|Bacteria,1MV6B@1224|Proteobacteria,1RPGF@1236|Gammaproteobacteria,1XVPD@135623|Vibrionales	135623|Vibrionales	V	MatE	-	-	-	ko:K03327	-	-	-	-	ko00000,ko02000	2.A.66.1	-	-	MatE
k141_4471_3	1121403.AUCV01000015_gene4690	1.78e-157	449.0	COG0601@1|root,COG0601@2|Bacteria,1MU8Z@1224|Proteobacteria,43AFB@68525|delta/epsilon subdivisions,2X5J0@28221|Deltaproteobacteria,2MPF4@213118|Desulfobacterales	28221|Deltaproteobacteria	EP	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02033,ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1
k141_4471_4	1121403.AUCV01000015_gene4689	2.71e-148	422.0	COG1173@1|root,COG1173@2|Bacteria,1MW3R@1224|Proteobacteria,43AQ5@68525|delta/epsilon subdivisions,2X63Y@28221|Deltaproteobacteria,2MPHJ@213118|Desulfobacterales	28221|Deltaproteobacteria	EP	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
k141_4471_5	1121403.AUCV01000015_gene4688	1.15e-263	734.0	COG0747@1|root,COG0747@2|Bacteria,1QTPR@1224|Proteobacteria,4347B@68525|delta/epsilon subdivisions,2X1YT@28221|Deltaproteobacteria,2MNI3@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_5
k141_4178_28	617140.AJZE01000008_gene3488	1.36e-133	380.0	COG0269@1|root,COG0269@2|Bacteria,1QWE4@1224|Proteobacteria,1RRCI@1236|Gammaproteobacteria,1XVVU@135623|Vibrionales	135623|Vibrionales	G	Orotidine 5'-phosphate decarboxylase / HUMPS family	ulaD	-	4.1.1.85	ko:K03078	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	M00550	R07125	RC01721	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase
k141_4178_29	675813.VIB_002245	1.92e-141	405.0	COG0561@1|root,COG0561@2|Bacteria,1PGMI@1224|Proteobacteria,1RPYI@1236|Gammaproteobacteria,1XV8T@135623|Vibrionales	135623|Vibrionales	S	of the HAD superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
k141_4178_30	1280001.BAOA01000007_gene3800	4.24e-133	380.0	COG0235@1|root,COG0235@2|Bacteria,1MU54@1224|Proteobacteria,1RMIP@1236|Gammaproteobacteria,1XUM8@135623|Vibrionales	135623|Vibrionales	G	COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases	araD	-	5.1.3.4	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	M00550	R05850	RC01479	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldolase_II
k141_4178_31	55601.VANGNB10_cII0119c	1.54e-80	242.0	COG1762@1|root,COG1762@2|Bacteria,1R4YX@1224|Proteobacteria,1RTCG@1236|Gammaproteobacteria,1XX1I@135623|Vibrionales	135623|Vibrionales	G	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2	ulaC	-	2.7.1.194	ko:K02821	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	M00283,M00550	R07671	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.7.1	-	-	PTS_EIIA_2
k141_195_3	933262.AXAM01000038_gene900	1.08e-48	159.0	COG0103@1|root,COG0103@2|Bacteria,1RD4A@1224|Proteobacteria,42SVI@68525|delta/epsilon subdivisions,2WP7T@28221|Deltaproteobacteria,2MJVD@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Belongs to the universal ribosomal protein uS9 family	rpsI	-	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
k141_195_4	439235.Dalk_2692	7.24e-70	214.0	COG0102@1|root,COG0102@2|Bacteria,1RA11@1224|Proteobacteria,42SD5@68525|delta/epsilon subdivisions,2WP5M@28221|Deltaproteobacteria,2MKE6@213118|Desulfobacterales	28221|Deltaproteobacteria	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rplM	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
k141_195_5	941449.dsx2_1853	1.51e-09	63.2	COG1437@1|root,COG1437@2|Bacteria,1N326@1224|Proteobacteria,42U83@68525|delta/epsilon subdivisions,2WQQR@28221|Deltaproteobacteria,2MBY3@213115|Desulfovibrionales	28221|Deltaproteobacteria	F	PFAM Adenylate cyclase	-	-	4.6.1.1	ko:K05873	ko00230,map00230	-	R00089,R00434	RC00295	ko00000,ko00001,ko01000	-	-	-	CYTH
k141_4911_1	55601.VANGNB10_cI0305c	2.42e-250	711.0	COG4666@1|root,COG4666@2|Bacteria,1MUNB@1224|Proteobacteria,1RMH7@1236|Gammaproteobacteria,1XUHS@135623|Vibrionales	135623|Vibrionales	S	transport system, fused permease components	-	-	-	-	-	-	-	-	-	-	-	-	DUF3394,DctM
k141_4911_2	345073.VC395_0472	2.01e-85	253.0	COG0589@1|root,COG0589@2|Bacteria,1RI97@1224|Proteobacteria,1SAXI@1236|Gammaproteobacteria,1XX3J@135623|Vibrionales	135623|Vibrionales	T	Universal stress protein	uspF	-	-	-	-	-	-	-	-	-	-	-	Usp
k141_4911_3	55601.VANGNB10_cI0302	1.6e-42	148.0	COG3250@1|root,COG3250@2|Bacteria,1NYBH@1224|Proteobacteria,1RZPC@1236|Gammaproteobacteria,1XSPV@135623|Vibrionales	135623|Vibrionales	G	COG3250 Beta-galactosidase beta-glucuronidase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_2_N
k141_3531_1	96561.Dole_3131	2.25e-98	295.0	COG0714@1|root,COG0714@2|Bacteria,1MV5I@1224|Proteobacteria,42N5A@68525|delta/epsilon subdivisions,2WKKI@28221|Deltaproteobacteria,2MIZW@213118|Desulfobacterales	28221|Deltaproteobacteria	S	AAA ATPase domain	clpB1	-	-	-	-	-	-	-	-	-	-	-	AAA,AAA_5
k141_3531_2	1304885.AUEY01000064_gene2129	5.12e-171	495.0	COG3552@1|root,COG3552@2|Bacteria,1MUHH@1224|Proteobacteria,42QBK@68525|delta/epsilon subdivisions,2WITZ@28221|Deltaproteobacteria,2MHM0@213118|Desulfobacterales	28221|Deltaproteobacteria	S	VWA domain containing CoxE-like protein	-	-	-	ko:K07161	-	-	-	-	ko00000	-	-	-	VWA_CoxE
k141_4181_1	666681.M301_0735	5.79e-30	112.0	COG0741@1|root,COG0741@2|Bacteria,1MZ4X@1224|Proteobacteria,2VKFN@28216|Betaproteobacteria,2KMXE@206350|Nitrosomonadales	206350|Nitrosomonadales	M	PFAM Lytic transglycosylase catalytic	-	-	-	-	-	-	-	-	-	-	-	-	SLT
k141_4181_2	1499967.BAYZ01000028_gene1277	3.27e-18	79.7	COG1534@1|root,COG1534@2|Bacteria	2|Bacteria	J	preribosome binding	yhbY	GO:0000027,GO:0000028,GO:0000966,GO:0000967,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0022607,GO:0022613,GO:0022618,GO:0034470,GO:0034471,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0042274,GO:0043021,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360,GO:1990275	-	ko:K07574	-	-	-	-	ko00000,ko03009	-	-	-	CRS1_YhbY
k141_3180_1	1238450.VIBNISOn1_1920010	6.36e-33	122.0	COG0583@1|root,COG0583@2|Bacteria,1MVHT@1224|Proteobacteria,1RN7G@1236|Gammaproteobacteria,1XT8V@135623|Vibrionales	135623|Vibrionales	K	Transcriptional activator	nhaR	GO:0003674,GO:0003700,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2001141	-	ko:K03717	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,LysR_substrate
k141_3180_2	243277.VC_0678	3.31e-44	145.0	COG0640@1|root,COG0640@2|Bacteria,1N72Q@1224|Proteobacteria,1SCH5@1236|Gammaproteobacteria,1XXWQ@135623|Vibrionales	135623|Vibrionales	K	transcriptional regulators	hlyU	GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044212,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:2000112,GO:2001141	-	ko:K22042	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5
k141_3180_3	55601.VANGNB10_cI0606c	1.94e-44	145.0	COG0268@1|root,COG0268@2|Bacteria,1MZ94@1224|Proteobacteria,1S9AI@1236|Gammaproteobacteria,1XXVB@135623|Vibrionales	135623|Vibrionales	J	Binds directly to 16S ribosomal RNA	rpsT	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02968	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S20p
k141_3180_4	223926.28805515	6.96e-303	834.0	COG0728@1|root,COG0728@2|Bacteria,1MUH0@1224|Proteobacteria,1RMXX@1236|Gammaproteobacteria,1XTUG@135623|Vibrionales	135623|Vibrionales	U	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane	murJ	GO:0000270,GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0006810,GO:0006869,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0010876,GO:0015647,GO:0015648,GO:0015835,GO:0015836,GO:0016020,GO:0016021,GO:0016043,GO:0022857,GO:0022884,GO:0030203,GO:0031224,GO:0031226,GO:0033036,GO:0034204,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0061024,GO:0065007,GO:0065008,GO:0070589,GO:0071554,GO:0071702,GO:0071704,GO:0071705,GO:0071840,GO:0071944,GO:0097035,GO:1901135,GO:1901137,GO:1901264,GO:1901505,GO:1901564,GO:1901566,GO:1901576	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
k141_3180_5	672.VV93_v1c06260	7.84e-183	513.0	COG0196@1|root,COG0196@2|Bacteria,1MV9I@1224|Proteobacteria,1RN44@1236|Gammaproteobacteria,1XTHQ@135623|Vibrionales	135623|Vibrionales	H	Belongs to the ribF family	ribF	-	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
k141_3180_6	1348635.BBJY01000008_gene1721	0.0	1706.0	COG0060@1|root,COG0060@2|Bacteria,1MVBQ@1224|Proteobacteria,1RMTF@1236|Gammaproteobacteria,1XSUS@135623|Vibrionales	135623|Vibrionales	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1,zf-FPG_IleRS
k141_3180_7	617140.AJZE01000014_gene1129	1.55e-94	278.0	COG0597@1|root,COG0597@2|Bacteria,1RGV9@1224|Proteobacteria,1S60E@1236|Gammaproteobacteria,1XT9S@135623|Vibrionales	135623|Vibrionales	MU	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	lspA	-	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
k141_3180_8	675815.VOA_003166	3.54e-193	540.0	COG0761@1|root,COG0761@2|Bacteria,1MU7G@1224|Proteobacteria,1RMN8@1236|Gammaproteobacteria,1XTYD@135623|Vibrionales	135623|Vibrionales	IM	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis	ispH	-	1.17.7.4	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05884,R08210	RC01137,RC01487	ko00000,ko00001,ko00002,ko01000	-	-	-	LYTB
k141_3180_10	1348635.BBJY01000008_gene1716	2.25e-46	151.0	2ED5M@1|root,3372C@2|Bacteria,1N2Z7@1224|Proteobacteria,1SEVD@1236|Gammaproteobacteria,1XY03@135623|Vibrionales	135623|Vibrionales	S	Protein of unknown function (DUF2799)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2799
k141_3180_11	243277.VC_0690	8.37e-160	454.0	COG2103@1|root,COG2103@2|Bacteria,1MVDR@1224|Proteobacteria,1RN3P@1236|Gammaproteobacteria,1XUH3@135623|Vibrionales	135623|Vibrionales	S	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate. Together with AnmK, is also required for the utilization of anhydro-N-acetylmuramic acid (anhMurNAc) either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling	murQ	-	4.2.1.126	ko:K07106	ko00520,ko01100,map00520,map01100	-	R08555	RC00397,RC00746	ko00000,ko00001,ko01000	-	-	-	SIS,SIS_2
k141_3180_12	870967.VIS19158_01654	4.8e-148	430.0	COG2377@1|root,COG2377@2|Bacteria,1MV4E@1224|Proteobacteria,1RNTZ@1236|Gammaproteobacteria,1XTEE@135623|Vibrionales	135623|Vibrionales	F	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling	anmK	-	2.7.1.170	ko:K09001	-	-	-	-	ko00000,ko01000	-	-	-	AnmK
k141_3180_13	243277.VC_0692	1.5e-164	468.0	COG1472@1|root,COG1472@2|Bacteria,1MVAJ@1224|Proteobacteria,1RMQF@1236|Gammaproteobacteria,1XU7E@135623|Vibrionales	135623|Vibrionales	G	Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides	nagZ	GO:0000270,GO:0003674,GO:0003824,GO:0004553,GO:0004563,GO:0006022,GO:0006807,GO:0008150,GO:0008152,GO:0009254,GO:0009273,GO:0009987,GO:0015929,GO:0016787,GO:0016798,GO:0030203,GO:0042546,GO:0043170,GO:0044085,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901564	3.2.1.52	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	M00628	R00022,R05963,R07809,R07810,R10831	RC00049	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyco_hydro_3
k141_3180_14	1191299.AJYX01000052_gene1536	1.87e-109	322.0	COG3279@1|root,COG3279@2|Bacteria,1MUE8@1224|Proteobacteria,1RMJJ@1236|Gammaproteobacteria,1XU8Z@135623|Vibrionales	135623|Vibrionales	K	COG3279 Response regulator of the LytR AlgR family	yehT	GO:0000156,GO:0000160,GO:0003674,GO:0007154,GO:0007165,GO:0008150,GO:0009987,GO:0023052,GO:0035556,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0060089,GO:0065007	-	ko:K02477	-	-	-	-	ko00000,ko02022	-	-	-	LytTR,Response_reg
k141_3180_15	675815.VOA_003158	3.3e-179	515.0	COG3275@1|root,COG3275@2|Bacteria,1QUB1@1224|Proteobacteria,1T1RX@1236|Gammaproteobacteria,1XU1C@135623|Vibrionales	135623|Vibrionales	T	regulator of cell autolysis	yehU	-	2.7.13.3	ko:K02478	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	5TM-5TMR_LYT,GAF_3,His_kinase,SpoVT_C
k141_1176_1	675814.VIC_001980	2.17e-114	342.0	COG0582@1|root,COG0582@2|Bacteria,1MU23@1224|Proteobacteria,1RMJ1@1236|Gammaproteobacteria,1XTXF@135623|Vibrionales	135623|Vibrionales	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Arm-DNA-bind_3,Phage_int_SAM_3,Phage_integrase
k141_1176_3	315749.Bcer98_0461	3.15e-12	70.1	COG3157@1|root,COG3157@2|Bacteria,1VXEW@1239|Firmicutes,4HX1T@91061|Bacilli,1ZGUH@1386|Bacillus	91061|Bacilli	L	nuclease activity	-	-	-	ko:K06887	-	-	-	-	ko00000	-	-	-	-
k141_3181_1	1313304.CALK_2278	2.68e-49	176.0	COG4191@1|root,COG4191@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
k141_3182_1	1304885.AUEY01000042_gene3589	5e-39	138.0	COG1842@1|root,COG1842@2|Bacteria,1R9BF@1224|Proteobacteria,42NZU@68525|delta/epsilon subdivisions,2WMMD@28221|Deltaproteobacteria,2MMDX@213118|Desulfobacterales	28221|Deltaproteobacteria	KT	PspA/IM30 family	-	-	-	ko:K03969	-	-	-	-	ko00000	-	-	-	PspA_IM30
k141_3182_2	237368.SCABRO_00965	1.75e-11	63.2	2CEGV@1|root,32RZV@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4178)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4178
k141_196_1	2423.NA23_0210380	1.56e-06	57.0	COG0463@1|root,COG0463@2|Bacteria,2GEG5@200918|Thermotogae	200918|Thermotogae	M	Glycosyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
k141_196_2	99598.Cal7507_4405	1.28e-51	183.0	COG0438@1|root,COG0438@2|Bacteria,1G27U@1117|Cyanobacteria,1HJI3@1161|Nostocales	1117|Cyanobacteria	M	PFAM Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
k141_196_3	649638.Trad_1868	1.44e-22	95.5	COG1045@1|root,COG1045@2|Bacteria,1WKUB@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	Bacterial transferase hexapeptide (six repeats)	-	-	2.3.1.30	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	M00021	R00586	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,SATase_N
k141_3532_1	335283.Neut_0901	3.08e-228	651.0	COG0367@1|root,COG0367@2|Bacteria,1MW4E@1224|Proteobacteria,2VHBY@28216|Betaproteobacteria,372CJ@32003|Nitrosomonadales	28216|Betaproteobacteria	F	Asparagine synthase	asnB1	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
k141_4912_2	768710.DesyoDRAFT_2108	1.97e-65	206.0	COG1280@1|root,COG1280@2|Bacteria,1TSNA@1239|Firmicutes,24CNE@186801|Clostridia	186801|Clostridia	E	PFAM Lysine exporter protein (LYSE YGGA)	-	-	-	ko:K11249	-	-	-	-	ko00000,ko02000	2.A.76.1.4	-	-	LysE
k141_4912_3	768710.DesyoDRAFT_2107	1.37e-120	352.0	COG2207@1|root,COG2207@2|Bacteria,1TPNZ@1239|Firmicutes,24949@186801|Clostridia	186801|Clostridia	K	AraC-like ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
k141_1177_1	1348635.BBJY01000002_gene3446	1.93e-223	642.0	COG2844@1|root,COG2844@2|Bacteria,1MV54@1224|Proteobacteria,1RN5T@1236|Gammaproteobacteria,1XU15@135623|Vibrionales	135623|Vibrionales	O	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen	glnD	GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006541,GO:0006542,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008773,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0070569,GO:0071704,GO:0140096,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.7.59	ko:K00990	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	-	-	-	ACT,GlnD_UR_UTase,HD,NTP_transf_2
k141_3183_1	1121094.KB894647_gene659	6.39e-46	155.0	COG0778@1|root,COG0778@2|Bacteria,4NMXW@976|Bacteroidetes,2FKZR@200643|Bacteroidia,4AMX5@815|Bacteroidaceae	976|Bacteroidetes	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
k141_3183_2	1304885.AUEY01000055_gene191	1.01e-07	54.3	COG0076@1|root,COG0076@2|Bacteria,1MWUX@1224|Proteobacteria,42MYA@68525|delta/epsilon subdivisions,2WKFB@28221|Deltaproteobacteria,2MIHP@213118|Desulfobacterales	28221|Deltaproteobacteria	E	PFAM Pyridoxal-dependent decarboxylase	-	-	4.1.1.15	ko:K01580	ko00250,ko00410,ko00430,ko00650,ko01100,ko01110,ko01120,ko02024,ko04727,ko04940,map00250,map00410,map00430,map00650,map01100,map01110,map01120,map02024,map04727,map04940	M00027	R00261,R00489,R01682,R02466	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	EF-hand_7,Pyridoxal_deC
k141_2806_1	1348635.BBJY01000003_gene3749	2.35e-27	108.0	COG0428@1|root,COG0428@2|Bacteria,1MWEZ@1224|Proteobacteria,1RNXU@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	Mediates zinc uptake. May also transport other divalent cations	zupT	GO:0000041,GO:0003674,GO:0005215,GO:0005381,GO:0005384,GO:0005385,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006824,GO:0006826,GO:0006828,GO:0006829,GO:0008150,GO:0008324,GO:0015075,GO:0015086,GO:0015087,GO:0015093,GO:0015318,GO:0015684,GO:0015691,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0034755,GO:0044464,GO:0046873,GO:0046915,GO:0051179,GO:0051234,GO:0055085,GO:0070574,GO:0070838,GO:0071421,GO:0071577,GO:0071944,GO:0072509,GO:0072511,GO:0098655,GO:0098660,GO:0098662,GO:1903874	-	ko:K07238	-	-	-	-	ko00000,ko02000	2.A.5.5	-	iECIAI39_1322.ECIAI39_3536	Zip
k141_2806_2	525898.Sdel_2193	0.0	1321.0	COG2972@1|root,COG5001@1|root,COG2972@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,43D0E@68525|delta/epsilon subdivisions	1224|Proteobacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF,GGDEF,HAMP,PAS_9,PocR
k141_2806_3	517433.PanABDRAFT_2743	2.42e-07	54.3	2D0US@1|root,32T9A@2|Bacteria,1N1YF@1224|Proteobacteria,1S9I4@1236|Gammaproteobacteria,3W0M6@53335|Pantoea	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_3533_1	10228.TriadP59449	0.000288	45.1	COG1012@1|root,KOG2456@2759|Eukaryota,38CW8@33154|Opisthokonta,3BDR1@33208|Metazoa	33208|Metazoa	C	Belongs to the aldehyde dehydrogenase family	ALDH3A2	GO:0000302,GO:0001561,GO:0001666,GO:0003674,GO:0003824,GO:0004028,GO:0004029,GO:0004030,GO:0004033,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005777,GO:0005778,GO:0005783,GO:0005789,GO:0005829,GO:0005886,GO:0006066,GO:0006081,GO:0006082,GO:0006629,GO:0006631,GO:0006643,GO:0006665,GO:0006714,GO:0006720,GO:0006721,GO:0006805,GO:0006807,GO:0006950,GO:0006979,GO:0007275,GO:0007399,GO:0007417,GO:0007422,GO:0007568,GO:0007584,GO:0008106,GO:0008150,GO:0008152,GO:0008284,GO:0008544,GO:0008610,GO:0009056,GO:0009058,GO:0009062,GO:0009410,GO:0009605,GO:0009628,GO:0009719,GO:0009725,GO:0009888,GO:0009987,GO:0009991,GO:0010033,GO:0010243,GO:0012505,GO:0014070,GO:0014074,GO:0016020,GO:0016021,GO:0016042,GO:0016054,GO:0016101,GO:0016491,GO:0016614,GO:0016616,GO:0016620,GO:0016899,GO:0016903,GO:0016999,GO:0017144,GO:0018479,GO:0019395,GO:0019752,GO:0019898,GO:0030148,GO:0030258,GO:0031090,GO:0031224,GO:0031312,GO:0031667,GO:0031903,GO:0031960,GO:0031984,GO:0032501,GO:0032502,GO:0032787,GO:0033306,GO:0033993,GO:0034308,GO:0034440,GO:0036293,GO:0042127,GO:0042175,GO:0042221,GO:0042406,GO:0042493,GO:0042579,GO:0042802,GO:0042803,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044249,GO:0044255,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044425,GO:0044432,GO:0044438,GO:0044439,GO:0044444,GO:0044446,GO:0044464,GO:0046292,GO:0046395,GO:0046458,GO:0046467,GO:0046577,GO:0046683,GO:0046983,GO:0048518,GO:0048522,GO:0048545,GO:0048731,GO:0048856,GO:0050061,GO:0050789,GO:0050794,GO:0050896,GO:0051384,GO:0051591,GO:0051716,GO:0052814,GO:0055114,GO:0065007,GO:0070482,GO:0070887,GO:0071466,GO:0071704,GO:0071944,GO:0072329,GO:0098588,GO:0098805,GO:0098827,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901698,GO:1901700,GO:1903173	1.2.1.3,1.2.1.5	ko:K00128,ko:K00129,ko:K04513	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00350,ko00360,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00980,ko00981,ko00982,ko01100,ko01110,ko01120,ko01130,ko04011,ko04014,ko04015,ko04022,ko04024,ko04062,ko04071,ko04072,ko04144,ko04150,ko04270,ko04310,ko04350,ko04360,ko04510,ko04520,ko04530,ko04611,ko04621,ko04660,ko04670,ko04722,ko04810,ko04921,ko04972,ko05100,ko05130,ko05133,ko05152,ko05200,ko05203,ko05204,ko05205,ko05206,ko05210,ko05418,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00350,map00360,map00380,map00410,map00561,map00620,map00625,map00903,map00980,map00981,map00982,map01100,map01110,map01120,map01130,map04011,map04014,map04015,map04022,map04024,map04062,map04071,map04072,map04144,map04150,map04270,map04310,map04350,map04360,map04510,map04520,map04530,map04611,map04621,map04660,map04670,map04722,map04810,map04921,map04972,map05100,map05130,map05133,map05152,map05200,map05203,map05204,map05205,map05206,map05210,map05418	M00135	R00264,R00631,R00710,R00711,R00904,R01752,R01986,R02536,R02537,R02549,R02678,R02695,R02697,R02940,R02957,R03283,R03300,R03302,R03869,R04065,R04506,R04882,R04883,R04888,R04889,R04891,R04892,R04903,R04996,R05050,R05237,R05238,R05286,R06366,R07104,R08146,R08282,R08283,R08307	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500,RC01735	ko00000,ko00001,ko00002,ko01000,ko04031,ko04131,ko04147	-	-	-	Aldedh
k141_3533_2	1230476.C207_00607	0.000401	48.5	COG1309@1|root,COG1309@2|Bacteria,1MVQV@1224|Proteobacteria,2TRPA@28211|Alphaproteobacteria,3JV5D@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	K	Bacterial transcriptional repressor C-terminal	MA20_09445	-	-	-	-	-	-	-	-	-	-	-	TetR_C_11,TetR_N
k141_3533_3	1430440.MGMSRv2_0963	6.7e-42	140.0	2E37W@1|root,32Y7J@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_1178_1	529507.PMI3429	1.77e-12	66.6	2DSCT@1|root,33FK4@2|Bacteria,1NNSB@1224|Proteobacteria,1SHIF@1236|Gammaproteobacteria,3Z3FX@583|Proteus	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_1178_2	991905.SL003B_2008	5.57e-38	134.0	COG1126@1|root,COG1126@2|Bacteria,1MU9Q@1224|Proteobacteria,2TQX2@28211|Alphaproteobacteria,4BPA2@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	E	ABC transporter	glnQ	-	3.6.3.21	ko:K02028,ko:K09972	ko02010,map02010	M00232,M00236	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.3,3.A.1.3.17,3.A.1.3.18,3.A.1.3.7,3.A.1.3.8	-	-	ABC_tran
k141_5176_1	598467.BrE312_4372	3.04e-155	446.0	COG1063@1|root,COG1063@2|Bacteria,1MWX0@1224|Proteobacteria,1RR1W@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Alcohol dehydrogenase GroES domain protein	yjjN	GO:0003674,GO:0003824,GO:0005975,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016052,GO:0016054,GO:0016491,GO:0016614,GO:0016616,GO:0019520,GO:0019583,GO:0019584,GO:0019752,GO:0032787,GO:0034193,GO:0034195,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044275,GO:0044281,GO:0044282,GO:0046176,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575	-	-	-	-	-	-	-	-	-	iSSON_1240.SSON_4504	ADH_N,ADH_zinc_N
k141_5176_2	701176.VIBRN418_06266	4.68e-166	470.0	COG1802@1|root,COG1802@2|Bacteria,1R56F@1224|Proteobacteria,1RNQY@1236|Gammaproteobacteria,1Y0HI@135623|Vibrionales	135623|Vibrionales	K	FCD domain	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
k141_5176_3	701176.VIBRN418_06271	8.96e-106	310.0	COG0800@1|root,COG0800@2|Bacteria,1MUVJ@1224|Proteobacteria,1RPDF@1236|Gammaproteobacteria,1XU29@135623|Vibrionales	135623|Vibrionales	G	COG0800 2-keto-3-deoxy-6-phosphogluconate aldolase	-	-	4.1.2.14,4.1.3.42	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	M00008,M00061,M00308,M00631	R00470,R05605	RC00307,RC00308,RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldolase
k141_5176_4	1028803.GG9_0221	1.65e-106	320.0	COG0524@1|root,COG0524@2|Bacteria,1MVG2@1224|Proteobacteria,1RNH5@1236|Gammaproteobacteria,1Y8A6@135625|Pasteurellales	135625|Pasteurellales	G	pfkB family carbohydrate kinase	kdgK	-	2.7.1.45	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00061,M00308,M00631	R01541	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PfkB
k141_5176_5	701176.VIBRN418_06281	1.91e-258	714.0	COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,1RNAM@1236|Gammaproteobacteria,1XTIW@135623|Vibrionales	135623|Vibrionales	G	TRAP-type C4-dicarboxylate transport system, large permease component	-	-	-	-	-	-	-	-	-	-	-	-	DctM
k141_5176_6	701176.VIBRN418_06286	1.89e-75	230.0	COG3090@1|root,COG3090@2|Bacteria,1NHC5@1224|Proteobacteria,1SIXV@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	Tripartite ATP-independent periplasmic transporters, DctQ component	-	-	-	-	-	-	-	-	-	-	-	-	DctQ
k141_5176_7	701176.VIBRN418_06291	2.87e-176	498.0	COG1638@1|root,COG1638@2|Bacteria,1MWAM@1224|Proteobacteria,1RSDU@1236|Gammaproteobacteria,1Y2J7@135623|Vibrionales	135623|Vibrionales	G	Bacterial extracellular solute-binding protein, family 7	-	-	-	-	-	-	-	-	-	-	-	-	DctP
k141_5176_8	701176.VIBRN418_06296	5.81e-39	143.0	COG0246@1|root,COG0246@2|Bacteria,1MVZ7@1224|Proteobacteria,1RQX5@1236|Gammaproteobacteria,1XUJB@135623|Vibrionales	135623|Vibrionales	C	Mannitol dehydrogenase C-terminal domain	-	-	1.1.1.58	ko:K00041	ko00040,ko01100,map00040,map01100	M00631	R02555	RC00085	ko00000,ko00001,ko00002,ko01000	-	-	-	Mannitol_dh,Mannitol_dh_C
k141_2447_1	1304885.AUEY01000002_gene412	5.51e-223	633.0	COG1166@1|root,COG1166@2|Bacteria,1MU80@1224|Proteobacteria,42M2B@68525|delta/epsilon subdivisions,2WJDZ@28221|Deltaproteobacteria,2MJ4U@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Pyridoxal-dependent decarboxylase, pyridoxal binding domain	speA	-	4.1.1.19	ko:K01585	ko00330,ko01100,map00330,map01100	M00133	R00566	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N
k141_2447_2	1304885.AUEY01000020_gene3498	3.81e-233	647.0	COG1748@1|root,COG1748@2|Bacteria,1NIU2@1224|Proteobacteria,42MHS@68525|delta/epsilon subdivisions,2WJQW@28221|Deltaproteobacteria,2MHRC@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Saccharopine dehydrogenase	-	-	1.5.1.7	ko:K00290	ko00300,ko00310,ko01100,ko01110,ko01130,ko01230,map00300,map00310,map01100,map01110,map01130,map01230	M00030,M00032	R00715	RC00217,RC01532	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_0902	Sacchrp_dh_C,Sacchrp_dh_NADP
k141_4191_1	177437.HRM2_32680	8.86e-39	139.0	COG5423@1|root,COG5423@2|Bacteria,1RM13@1224|Proteobacteria,42UAM@68525|delta/epsilon subdivisions,2WPBJ@28221|Deltaproteobacteria,2MKK2@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Predicted metal-binding protein (DUF2284)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2284
k141_3869_1	1191523.MROS_1921	7.18e-87	269.0	COG0126@1|root,COG0126@2|Bacteria	2|Bacteria	F	phosphoglycerate kinase activity	pgk	GO:0003674,GO:0003824,GO:0004618,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576	2.7.2.3,5.3.1.1	ko:K00927,ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01015,R01512	RC00002,RC00043,RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
k141_3869_2	65489.OBART08G01630.1	2.89e-25	102.0	COG0057@1|root,KOG0657@2759|Eukaryota,37HSA@33090|Viridiplantae,3GAGX@35493|Streptophyta,3M3W9@4447|Liliopsida,3I46A@38820|Poales	35493|Streptophyta	G	Glyceraldehyde-3-phosphate dehydrogenase	-	GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0005575,GO:0008150,GO:0008152,GO:0009314,GO:0009416,GO:0009628,GO:0016491,GO:0016620,GO:0016903,GO:0032991,GO:0036094,GO:0042301,GO:0043167,GO:0043168,GO:0043891,GO:0048037,GO:0050662,GO:0050896,GO:0051287,GO:0055114,GO:0070403,GO:0097159,GO:1901265,GO:1901363	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
k141_1481_1	1116375.VEJY3_23791	3.17e-52	174.0	COG1609@1|root,COG1609@2|Bacteria,1RKJ6@1224|Proteobacteria,1SMZS@1236|Gammaproteobacteria,1XSDZ@135623|Vibrionales	135623|Vibrionales	K	Sucrose operon repressor	-	-	-	ko:K03484	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
k141_2164_1	1304885.AUEY01000090_gene2887	1.15e-89	281.0	COG0303@1|root,COG2191@1|root,COG0303@2|Bacteria,COG2191@2|Bacteria,1MYKY@1224|Proteobacteria,42NIJ@68525|delta/epsilon subdivisions,2WJ0M@28221|Deltaproteobacteria,2MPIP@213118|Desulfobacterales	28221|Deltaproteobacteria	CH	FmdE, Molybdenum formylmethanofuran dehydrogenase operon	-	-	1.2.7.12	ko:K11261	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00567	R03015,R08060,R11743	RC00197,RC00323	ko00000,ko00001,ko00002,ko01000	-	-	-	FmdE,MoCF_biosynth
k141_2164_2	44251.PDUR_13605	4.16e-77	246.0	COG2896@1|root,COG2896@2|Bacteria,1TP89@1239|Firmicutes,4HAKQ@91061|Bacilli,26W9I@186822|Paenibacillaceae	91061|Bacilli	H	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate	moaA	-	4.1.99.22	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394	RC03420	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Mob_synth_C,Radical_SAM
k141_2164_3	1123251.ATWM01000001_gene706	2.51e-12	74.3	COG3302@1|root,COG3302@2|Bacteria,2GV8F@201174|Actinobacteria	201174|Actinobacteria	S	DMSO reductase anchor subunit (DmsC)	dmsC	-	-	ko:K07308	ko00920,map00920	-	R09501	RC02555	ko00000,ko00001,ko02000	5.A.3.3	-	-	DmsC
k141_2164_4	1487923.DP73_13855	9.96e-112	325.0	COG0437@1|root,COG0437@2|Bacteria,1V35R@1239|Firmicutes,24Z9K@186801|Clostridia,263IA@186807|Peptococcaceae	1239|Firmicutes	C	Fe-S-cluster-containing hydrogenase	-	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_11,Fer4_3,Fer4_4
k141_2164_5	312309.VF_A0082	1.18e-69	252.0	COG0243@1|root,COG0243@2|Bacteria,1NR6J@1224|Proteobacteria,1RMVE@1236|Gammaproteobacteria,1XW7C@135623|Vibrionales	135623|Vibrionales	C	Molybdopterin oxidoreductase Fe4S4 domain	-	-	1.8.5.3	ko:K07306	ko00920,map00920	-	R09501	RC02555	ko00000,ko00001,ko01000,ko02000	5.A.3.3	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
k141_212_1	223926.28807587	4.31e-18	80.9	COG3073@1|root,COG3073@2|Bacteria,1R4U0@1224|Proteobacteria,1RN98@1236|Gammaproteobacteria,1XSUI@135623|Vibrionales	135623|Vibrionales	T	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E	rseA	-	-	ko:K03597	-	-	-	-	ko00000,ko03021	-	-	-	RseA_C,RseA_N
k141_212_5	312309.VF_2096	1.94e-44	145.0	COG2938@1|root,COG2938@2|Bacteria,1N7P4@1224|Proteobacteria,1SCKB@1236|Gammaproteobacteria,1XXUM@135623|Vibrionales	135623|Vibrionales	S	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH and other flavinylated proteins as well	sdhE	GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016999,GO:0017144,GO:0018065,GO:0018293,GO:0019538,GO:0019752,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350,GO:1901564	-	ko:K09159	-	-	-	-	ko00000,ko02048	-	-	-	Sdh5
k141_212_6	345073.VC395_2587	1.35e-118	351.0	COG0354@1|root,COG0354@2|Bacteria,1N852@1224|Proteobacteria,1RPWB@1236|Gammaproteobacteria,1XTWH@135623|Vibrionales	135623|Vibrionales	J	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication	ygfZ	GO:0006790,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0044085,GO:0044237,GO:0051186,GO:0071840	-	ko:K06980	-	-	-	-	ko00000,ko03016	-	-	-	GCV_T
k141_212_7	1238450.VIBNISOn1_80017	4.22e-36	122.0	2CTIP@1|root,32STK@2|Bacteria,1MZ8V@1224|Proteobacteria,1SEQR@1236|Gammaproteobacteria,1XYB9@135623|Vibrionales	135623|Vibrionales	S	Protein of unknown function (DUF1107)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1107
k141_212_8	1517681.HW45_19710	2.25e-176	503.0	COG0654@1|root,COG0654@2|Bacteria,1MU6I@1224|Proteobacteria,1RND5@1236|Gammaproteobacteria,1XU9H@135623|Vibrionales	135623|Vibrionales	CH	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	visC	-	-	ko:K18800	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04987,R08768	RC00046	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_3
k141_3198_1	225937.HP15_3665	5.31e-37	150.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,1RQZD@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,sCache_3_3
k141_3198_2	1304885.AUEY01000033_gene1917	0.0	920.0	COG2804@1|root,COG3437@1|root,COG2804@2|Bacteria,COG3437@2|Bacteria,1MU7V@1224|Proteobacteria,42M51@68525|delta/epsilon subdivisions,2WKXB@28221|Deltaproteobacteria,2MMWV@213118|Desulfobacterales	28221|Deltaproteobacteria	T	General secretory system II protein E domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,T2SSE,T2SSE_N
k141_3198_3	1121403.AUCV01000013_gene3920	9.56e-215	608.0	COG1167@1|root,COG1167@2|Bacteria,1MV6F@1224|Proteobacteria,42MID@68525|delta/epsilon subdivisions,2WJYT@28221|Deltaproteobacteria,2MMWN@213118|Desulfobacterales	28221|Deltaproteobacteria	EK	helix_turn_helix gluconate operon transcriptional repressor	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2,GntR
k141_3198_4	1121918.ARWE01000001_gene2998	6.26e-67	215.0	COG0697@1|root,COG0697@2|Bacteria,1MXJY@1224|Proteobacteria,42RNT@68525|delta/epsilon subdivisions,2WNHN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
k141_2461_1	118005.AWNK01000004_gene1115	8.33e-15	72.8	COG1262@1|root,COG1262@2|Bacteria	2|Bacteria	T	PFAM Formylglycine-generating sulfatase enzyme	-	-	-	-	-	-	-	-	-	-	-	-	SapC
k141_2461_2	340177.Cag_1407	9.43e-211	616.0	COG0845@1|root,COG1994@1|root,COG0845@2|Bacteria,COG1994@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	ko:K01993,ko:K13408,ko:K16922	ko04626,map04626	M00339	-	-	ko00000,ko00001,ko00002,ko01002,ko02000,ko02044	8.A.1	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
k141_2461_3	340177.Cag_1408	2.59e-121	374.0	COG0845@1|root,COG0845@2|Bacteria	2|Bacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02004,ko:K07798	ko02020,map02020	M00258	-	-	ko00000,ko00001,ko00002,ko02000	2.A.6.1.4,3.A.1,8.A.1	-	-	FtsX,HlyD_3,HlyD_D23,MacB_PCD
k141_2461_4	1504672.669783581	7.73e-15	74.7	COG0845@1|root,COG0845@2|Bacteria	2|Bacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	cusB	-	-	ko:K13888	-	M00709	-	-	ko00000,ko00002,ko02000	8.A.1	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
k141_213_2	613026.HRAG_01042	2.31e-07	55.5	COG0835@1|root,COG0835@2|Bacteria,1RAH1@1224|Proteobacteria,42S69@68525|delta/epsilon subdivisions,2YP0K@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	chemotaxis protein	cheW	-	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
k141_2165_1	1348635.BBJY01000005_gene3336	1.13e-212	599.0	COG1785@1|root,COG1785@2|Bacteria,1MXI2@1224|Proteobacteria,1RNG8@1236|Gammaproteobacteria,1XTK7@135623|Vibrionales	135623|Vibrionales	P	Belongs to the alkaline phosphatase family	-	-	3.1.3.1	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	M00126	R02135,R04620	RC00017	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	-	-	-	Alk_phosphatase
k141_2462_1	1304885.AUEY01000042_gene3589	2e-27	105.0	COG1842@1|root,COG1842@2|Bacteria,1R9BF@1224|Proteobacteria,42NZU@68525|delta/epsilon subdivisions,2WMMD@28221|Deltaproteobacteria,2MMDX@213118|Desulfobacterales	28221|Deltaproteobacteria	KT	PspA/IM30 family	-	-	-	ko:K03969	-	-	-	-	ko00000	-	-	-	PspA_IM30
k141_2462_2	1304885.AUEY01000042_gene3588	1.78e-42	142.0	291R8@1|root,2ZPB9@2|Bacteria,1N1MA@1224|Proteobacteria,42UBU@68525|delta/epsilon subdivisions,2WQ2C@28221|Deltaproteobacteria,2MM65@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Putative bacterial sensory transduction regulator	-	-	-	-	-	-	-	-	-	-	-	-	YbjN
k141_2166_1	1121396.KB892997_gene461	6.35e-14	68.2	COG1555@1|root,COG1555@2|Bacteria,1PU4P@1224|Proteobacteria,42VEG@68525|delta/epsilon subdivisions,2WSQJ@28221|Deltaproteobacteria,2MMC6@213118|Desulfobacterales	28221|Deltaproteobacteria	L	TIGRFAM competence protein ComEA helix-hairpin-helix repeat	-	-	-	ko:K02237	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	HHH_3
k141_4194_1	1248232.BANQ01000182_gene200	4.65e-96	295.0	COG4974@1|root,COG4974@2|Bacteria,1NY1A@1224|Proteobacteria,1RN33@1236|Gammaproteobacteria,1XTA8@135623|Vibrionales	135623|Vibrionales	L	Transposase ISVa5 (IS66-family	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS66,DDE_Tnp_IS66_C,LZ_Tnp_IS66,zf-IS66
k141_4655_17	1219065.VPR01S_05_00960	8.58e-83	248.0	COG0225@1|root,COG0225@2|Bacteria,1RCQP@1224|Proteobacteria,1S2S1@1236|Gammaproteobacteria,1XWVM@135623|Vibrionales	135623|Vibrionales	C	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	-	-	1.8.4.11	ko:K07304	-	-	-	-	ko00000,ko01000	-	-	-	PMSR
k141_4655_18	1278307.KB906980_gene4142	0.0	1044.0	COG0025@1|root,COG0025@2|Bacteria,1MW5T@1224|Proteobacteria,1RPH6@1236|Gammaproteobacteria,2QIQN@267894|Psychromonadaceae	1236|Gammaproteobacteria	P	Cyclic nucleotide-monophosphate binding domain	-	-	-	ko:K03316	-	-	-	-	ko00000	2.A.36	-	-	Na_H_Exchanger,cNMP_binding
k141_4655_20	945543.VIBR0546_06812	6.04e-132	380.0	COG0561@1|root,COG0561@2|Bacteria,1Q5HK@1224|Proteobacteria,1RQ8H@1236|Gammaproteobacteria,1XTJJ@135623|Vibrionales	135623|Vibrionales	S	hydrolases of the HAD superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
k141_4655_22	98439.AJLL01000034_gene2882	2.22e-27	112.0	COG0797@1|root,COG0797@2|Bacteria,1G0XF@1117|Cyanobacteria,1JH60@1189|Stigonemataceae	1117|Cyanobacteria	M	Lytic transglycolase	rlpA	-	-	ko:K03642	-	-	-	-	ko00000	-	-	-	DPBB_1
k141_4655_23	1499684.CCNP01000019_gene2206	6.04e-75	230.0	COG0406@1|root,COG0406@2|Bacteria,1VDCB@1239|Firmicutes,249VH@186801|Clostridia,36GCW@31979|Clostridiaceae	186801|Clostridia	G	Belongs to the phosphoglycerate mutase family	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
k141_4655_25	378806.STAUR_0313	1.51e-13	76.6	COG2885@1|root,COG2885@2|Bacteria,1R4WG@1224|Proteobacteria,42TD5@68525|delta/epsilon subdivisions,2WP3U@28221|Deltaproteobacteria,2YXHM@29|Myxococcales	28221|Deltaproteobacteria	M	OmpA family	-	-	-	ko:K03286	-	-	-	-	ko00000,ko02000	1.B.6	-	-	OMP_b-brl,OmpA,TSP_3
k141_4655_26	1219077.VAZ01S_087_00180	3.03e-70	216.0	COG0545@1|root,COG0545@2|Bacteria,1RCWV@1224|Proteobacteria,1S7UP@1236|Gammaproteobacteria,1XWX0@135623|Vibrionales	135623|Vibrionales	O	COG0545 FKBP-type peptidyl-prolyl cis-trans isomerases 1	-	-	5.2.1.8	ko:K01802	-	-	-	-	ko00000,ko01000	-	-	-	FKBP_C,FKBP_N
k141_4655_27	1348635.BBJY01000006_gene417	4.77e-83	251.0	COG0637@1|root,COG0637@2|Bacteria,1PUMZ@1224|Proteobacteria,1RNJC@1236|Gammaproteobacteria,1XVSG@135623|Vibrionales	135623|Vibrionales	S	phosphatase phosphohexomutase	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
k141_4655_28	641107.CDLVIII_5292	2.8e-93	284.0	COG3711@1|root,COG3711@2|Bacteria,1TT5A@1239|Firmicutes,24931@186801|Clostridia,36GUF@31979|Clostridiaceae	186801|Clostridia	K	CAT RNA binding domain	-	-	-	ko:K03488	-	-	-	-	ko00000,ko03000	-	-	-	CAT_RBD,PRD
k141_4655_29	586416.GZ22_13035	1.39e-281	778.0	COG2723@1|root,COG2723@2|Bacteria,1TP19@1239|Firmicutes,4HA1W@91061|Bacilli	91061|Bacilli	G	Belongs to the glycosyl hydrolase 1 family	-	-	3.2.1.86	ko:K01223	ko00010,ko00500,map00010,map00500	-	R00839,R05133,R05134	RC00049,RC00171,RC00714	ko00000,ko00001,ko01000	-	GT1	-	Glyco_hydro_1
k141_2866_1	398512.JQKC01000001_gene2152	4.34e-65	218.0	COG0635@1|root,COG1051@1|root,COG0635@2|Bacteria,COG1051@2|Bacteria,1TST7@1239|Firmicutes,249C3@186801|Clostridia,3WHXH@541000|Ruminococcaceae	186801|Clostridia	F	Belongs to the Nudix hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX,Radical_SAM
k141_3671_2	335543.Sfum_2553	2.99e-14	77.0	COG4966@1|root,COG4966@2|Bacteria,1Q8WE@1224|Proteobacteria,439J3@68525|delta/epsilon subdivisions,2X4VK@28221|Deltaproteobacteria,2MSHQ@213462|Syntrophobacterales	28221|Deltaproteobacteria	NU	Pfam:N_methyl_2	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
k141_3671_3	177439.DP1459	0.000931	44.7	COG4967@1|root,COG4967@2|Bacteria	2|Bacteria	NU	type IV pilus modification protein PilV	ppdC	-	-	ko:K02671,ko:K02681	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	N_methyl,T2SSppdC
k141_3671_5	1384054.N790_04575	1.38e-99	350.0	COG1404@1|root,COG3419@1|root,COG1404@2|Bacteria,COG3419@2|Bacteria,1NUAV@1224|Proteobacteria,1RPV3@1236|Gammaproteobacteria,1X3K8@135614|Xanthomonadales	135614|Xanthomonadales	NU	Tfp pilus assembly protein, tip-associated adhesin PilY1	-	-	-	ko:K02674	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	Neisseria_PilC,PPC
k141_2552_1	869213.JCM21142_93516	5.15e-27	103.0	COG1396@1|root,COG1396@2|Bacteria,4NU6M@976|Bacteroidetes,47SIV@768503|Cytophagia	976|Bacteroidetes	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
k141_4675_1	326297.Sama_1442	6.31e-34	125.0	COG3340@1|root,COG3340@2|Bacteria,1NBN5@1224|Proteobacteria,1RYUM@1236|Gammaproteobacteria,2Q8W6@267890|Shewanellaceae	1236|Gammaproteobacteria	O	Hydrolyzes dipeptides containing N-terminal aspartate residues. May play a role in allowing the cell to use peptide aspartate to spare carbon otherwise required for the synthesis of the aspartate family of amino acids	pepE	GO:0003674,GO:0003824,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:0140096,GO:1901564	3.4.13.21	ko:K05995	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S51
k141_4675_2	349521.HCH_01073	2.49e-58	191.0	COG1385@1|root,COG1385@2|Bacteria,1MZBG@1224|Proteobacteria,1S0HM@1236|Gammaproteobacteria,1XJ5U@135619|Oceanospirillales	135619|Oceanospirillales	J	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit	-	-	-	-	-	-	-	-	-	-	-	-	Methyltrans_RNA
k141_3672_1	1123487.KB892857_gene2474	2.44e-14	79.3	COG0705@1|root,COG0705@2|Bacteria,1MYFP@1224|Proteobacteria,2VPBJ@28216|Betaproteobacteria	28216|Betaproteobacteria	S	PFAM Rhomboid family protein	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
k141_3969_1	1121396.KB892913_gene170	4.19e-180	568.0	COG0304@1|root,COG1028@1|root,COG2070@1|root,COG3321@1|root,COG0304@2|Bacteria,COG1028@2|Bacteria,COG2070@2|Bacteria,COG3321@2|Bacteria,1R89Z@1224|Proteobacteria,42NGA@68525|delta/epsilon subdivisions,2WJK3@28221|Deltaproteobacteria,2MIK4@213118|Desulfobacterales	28221|Deltaproteobacteria	IQ	Beta-ketoacyl synthase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_1,KAsynt_C_assoc,KR,Ketoacyl-synt_C,NMO,PP-binding,PS-DH,ketoacyl-synt
k141_1981_1	517418.Ctha_0953	6.86e-26	112.0	COG1629@1|root,COG4771@2|Bacteria,1FDNG@1090|Chlorobi	1090|Chlorobi	M	TonB-dependent Receptor Plug Domain	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
k141_1981_2	386456.JQKN01000009_gene1185	2.69e-29	116.0	arCOG01632@1|root,arCOG01632@2157|Archaea,2XWWZ@28890|Euryarchaeota,23PM0@183925|Methanobacteria	183925|Methanobacteria	Q	rRNA small subunit methyltransferase G	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
k141_4295_4	1283284.AZUK01000001_gene2537	4.17e-64	203.0	COG1309@1|root,COG1309@2|Bacteria,1MZ9E@1224|Proteobacteria,1S5F3@1236|Gammaproteobacteria,1Y66E@135624|Aeromonadales	135624|Aeromonadales	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_7,TetR_N
k141_4295_5	1348635.BBJY01000004_gene2917	1e-200	573.0	COG1538@1|root,COG1538@2|Bacteria,1MUZZ@1224|Proteobacteria,1RQEP@1236|Gammaproteobacteria,1XY0Z@135623|Vibrionales	135623|Vibrionales	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
k141_4295_6	243277.VC_1410	1.73e-163	471.0	COG1566@1|root,COG1566@2|Bacteria,1MU7I@1224|Proteobacteria,1RMAD@1236|Gammaproteobacteria,1XW5D@135623|Vibrionales	135623|Vibrionales	V	COG1566 Multidrug resistance efflux pump	-	-	-	ko:K03543	-	M00701	-	-	ko00000,ko00002,ko02000	8.A.1.1	-	-	Biotin_lipoyl_2,HlyD,HlyD_3,HlyD_D23
k141_4295_7	1348635.BBJY01000004_gene2919	1.93e-285	790.0	COG0477@1|root,COG2814@2|Bacteria,1MU1I@1224|Proteobacteria,1RNTG@1236|Gammaproteobacteria,1XTM8@135623|Vibrionales	135623|Vibrionales	P	COG0477 Permeases of the major facilitator superfamily	emrB	-	-	ko:K03446	-	M00701	-	-	ko00000,ko00002,ko02000	2.A.1.3	-	-	MFS_1,SATase_N
k141_4295_8	675814.VIC_000457	1.15e-22	100.0	2A6R1@1|root,30VJ5@2|Bacteria,1RGD8@1224|Proteobacteria,1S593@1236|Gammaproteobacteria,1XSR7@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_4295_9	1117318.PRUB_06405	3.99e-61	203.0	COG0745@1|root,COG0745@2|Bacteria,1QC0H@1224|Proteobacteria,1RNF6@1236|Gammaproteobacteria,2Q0M2@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	T	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
k141_4295_10	1279015.KB908460_gene2875	5.61e-61	189.0	COG0720@1|root,COG0720@2|Bacteria,1RI4P@1224|Proteobacteria,1S3T6@1236|Gammaproteobacteria,1Y68Q@135624|Aeromonadales	135624|Aeromonadales	H	6-pyruvoyl tetrahydropterin synthase	-	-	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	PTPS
k141_4295_13	29495.EA26_18675	1.86e-123	362.0	COG0583@1|root,COG0583@2|Bacteria,1MWUP@1224|Proteobacteria,1RNIC@1236|Gammaproteobacteria,1XSZG@135623|Vibrionales	135623|Vibrionales	K	Controls the transcription of genes involved in arginine and lysine metabolism	argP	GO:0003674,GO:0003700,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2001141	-	ko:K05596	-	-	-	-	ko00000,ko03000,ko03036	-	-	-	HTH_1,LysR_substrate
k141_4295_14	1238450.VIBNISOn1_80006	2.18e-76	235.0	COG1279@1|root,COG1279@2|Bacteria,1RD6B@1224|Proteobacteria,1RR03@1236|Gammaproteobacteria,1XUSK@135623|Vibrionales	135623|Vibrionales	S	COG1279 Lysine efflux permease	argO	-	-	ko:K06895	-	-	-	-	ko00000,ko02000	2.A.75.1	-	-	LysE
k141_4295_15	675817.VDA_001599	0.0	1375.0	COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1143@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1143@2|Bacteria,1MVM0@1224|Proteobacteria,1RNNX@1236|Gammaproteobacteria,1XVUA@135623|Vibrionales	135623|Vibrionales	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	nifJ	-	1.2.7.1	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00173,M00307	R01196,R10866	RC00004,RC02742	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	EKR,Fer4,Fer4_16,Fer4_6,PFOR_II,POR,POR_N,TPP_enzyme_C
k141_4295_16	1517681.HW45_16240	4.25e-77	240.0	COG3142@1|root,COG3142@2|Bacteria,1MV5W@1224|Proteobacteria,1RMC1@1236|Gammaproteobacteria,1XSG9@135623|Vibrionales	135623|Vibrionales	P	Participates in the control of copper homeostasis	cutC	-	-	ko:K06201	-	-	-	-	ko00000	-	-	-	CutC
k141_4295_17	1269813.ATUL01000024_gene698	8.16e-14	72.8	COG4974@1|root,COG4974@2|Bacteria,1MVAN@1224|Proteobacteria,1RMSS@1236|Gammaproteobacteria,1WWPX@135613|Chromatiales	135613|Chromatiales	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
k141_4295_18	506534.Rhein_3413	2.19e-20	89.4	COG0582@1|root,COG0582@2|Bacteria,1QUFZ@1224|Proteobacteria,1T1XN@1236|Gammaproteobacteria,1X2S8@135613|Chromatiales	135613|Chromatiales	L	Phage integrase, N-terminal SAM-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
k141_4295_19	1051646.VITU9109_14733	6.54e-82	254.0	29XW5@1|root,30JNI@2|Bacteria,1QKDG@1224|Proteobacteria,1TIH6@1236|Gammaproteobacteria,1XZ48@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_619_1	1122169.AREN01000023_gene1669	6.28e-317	930.0	COG5635@1|root,COG5635@2|Bacteria,1NC67@1224|Proteobacteria,1RQJ1@1236|Gammaproteobacteria,1JFS6@118969|Legionellales	118969|Legionellales	T	Nacht domain	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_4676_1	1353276.JADR01000006_gene1083	2.2e-20	93.2	COG4191@1|root,COG4191@2|Bacteria,4NEJX@976|Bacteroidetes,1HXCA@117743|Flavobacteriia	976|Bacteroidetes	T	COG0642 Signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Y_Y_Y
k141_4676_2	1304885.AUEY01000020_gene3476	9.07e-79	244.0	2C96H@1|root,2Z7Q6@2|Bacteria,1PQG4@1224|Proteobacteria	1224|Proteobacteria	S	Sulfotransferase	raxST	-	-	ko:K13472	ko04626,map04626	-	-	-	ko00000,ko00001	-	-	-	Sulfotransfer_3
k141_1982_1	243265.plu3511	3.46e-44	150.0	COG0454@1|root,COG0456@2|Bacteria,1RI35@1224|Proteobacteria,1S66W@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	Acetyltransferase	yjaB	-	-	ko:K03827	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_10
k141_3970_1	1111728.ATYS01000028_gene2669	4.75e-178	508.0	COG3192@1|root,COG3192@2|Bacteria,1NPK6@1224|Proteobacteria,1S0MH@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	ethanolamine utilization protein	eutH	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K04023	-	-	-	-	ko00000	-	-	-	EutH
k141_2553_1	1408439.JHXW01000002_gene550	2.1e-12	64.7	COG0703@1|root,COG0703@2|Bacteria,37CC4@32066|Fusobacteria	32066|Fusobacteria	E	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_18
k141_2553_2	1232437.KL661986_gene3654	4.51e-179	506.0	COG3547@1|root,COG3547@2|Bacteria,1NGR7@1224|Proteobacteria,42NNQ@68525|delta/epsilon subdivisions,2WM2H@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	PFAM transposase IS116 IS110 IS902 family	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k141_4677_1	1265505.ATUG01000003_gene463	1.01e-33	125.0	COG1932@1|root,COG1932@2|Bacteria,1MUB5@1224|Proteobacteria,42MEN@68525|delta/epsilon subdivisions,2WIYF@28221|Deltaproteobacteria,2MIJH@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine	serC	-	2.6.1.52	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	M00020,M00124	R04173,R05085	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
k141_4677_2	1265505.ATUG01000003_gene462	6.18e-35	132.0	COG0111@1|root,COG0111@2|Bacteria,1MU5Z@1224|Proteobacteria,42M1C@68525|delta/epsilon subdivisions,2WIZQ@28221|Deltaproteobacteria,2MHQ6@213118|Desulfobacterales	28221|Deltaproteobacteria	E	D-isomer specific 2-hydroxyacid dehydrogenase catalytic	-	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C,ACT
k141_1983_2	8010.XP_010867023.1	1.85e-06	52.0	COG0666@1|root,KOG0504@2759|Eukaryota,39S8I@33154|Opisthokonta,3BKQB@33208|Metazoa,3D0U5@33213|Bilateria,485C5@7711|Chordata,49692@7742|Vertebrata,49QI5@7898|Actinopterygii	33208|Metazoa	S	and ankyrin repeat domains 1	FANK1	GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005829,GO:0005929,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0010941,GO:0010942,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031974,GO:0031981,GO:0042981,GO:0042995,GO:0043065,GO:0043066,GO:0043067,GO:0043068,GO:0043069,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044093,GO:0044422,GO:0044424,GO:0044428,GO:0044441,GO:0044444,GO:0044446,GO:0044463,GO:0044464,GO:0045893,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051090,GO:0051091,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0060548,GO:0065007,GO:0065009,GO:0070013,GO:0080090,GO:0097546,GO:0120025,GO:0120038,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141	-	-	-	-	-	-	-	-	-	-	Ank,Ank_2,Ank_4,Ank_5
k141_4296_1	933262.AXAM01000001_gene437	1.36e-117	339.0	COG2191@1|root,COG2191@2|Bacteria,1RBNI@1224|Proteobacteria,42QZP@68525|delta/epsilon subdivisions,2WMY0@28221|Deltaproteobacteria,2MJH4@213118|Desulfobacterales	28221|Deltaproteobacteria	C	FmdE, Molybdenum formylmethanofuran dehydrogenase operon	-	-	1.2.7.12	ko:K11261	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00567	R03015,R08060,R11743	RC00197,RC00323	ko00000,ko00001,ko00002,ko01000	-	-	-	FmdE,zf-dskA_traR
k141_2554_1	1232410.KI421412_gene389	1.79e-18	88.2	COG1629@1|root,COG4771@2|Bacteria,1MXAE@1224|Proteobacteria,43BVQ@68525|delta/epsilon subdivisions,2WKWT@28221|Deltaproteobacteria,43S1T@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	TonB-dependent Receptor Plug Domain	-	-	-	-	-	-	-	-	-	-	-	-	Plug
k141_3261_1	1232437.KL661978_gene3854	1.04e-19	82.4	COG1826@1|root,COG1826@2|Bacteria,1NI3F@1224|Proteobacteria,42VIZ@68525|delta/epsilon subdivisions,2WRC5@28221|Deltaproteobacteria,2MM5W@213118|Desulfobacterales	28221|Deltaproteobacteria	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system	tatB	-	-	ko:K03116,ko:K03117	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
k141_3261_2	1304885.AUEY01000002_gene285	2.24e-76	239.0	COG1082@1|root,COG1082@2|Bacteria,1N8KJ@1224|Proteobacteria,42SR1@68525|delta/epsilon subdivisions,2WP5P@28221|Deltaproteobacteria,2MNKD@213118|Desulfobacterales	28221|Deltaproteobacteria	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
k141_3261_3	269798.CHU_3089	4.21e-71	251.0	COG0642@1|root,COG0784@1|root,COG2198@1|root,COG5278@1|root,COG0784@2|Bacteria,COG2198@2|Bacteria,COG2205@2|Bacteria,COG5278@2|Bacteria,4NDXU@976|Bacteroidetes,47JK3@768503|Cytophagia	976|Bacteroidetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISM_7TM,CHASE3,GAF,HATPase_c,HNOBA,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
k141_622_1	1322246.BN4_11384	1.2e-34	126.0	COG1309@1|root,COG1309@2|Bacteria,1NP72@1224|Proteobacteria,42T8H@68525|delta/epsilon subdivisions,2WPNA@28221|Deltaproteobacteria,2MASD@213115|Desulfovibrionales	28221|Deltaproteobacteria	K	regulatory protein TetR	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_6,TetR_N
k141_2297_1	1219076.N646_0045	5.24e-123	364.0	COG4591@1|root,COG4591@2|Bacteria,1MVV7@1224|Proteobacteria,1RMP9@1236|Gammaproteobacteria,1XSJ2@135623|Vibrionales	135623|Vibrionales	M	COG4591 ABC-type transport system, involved in lipoprotein release, permease component	lolE	-	-	ko:K09808	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125	-	-	FtsX,MacB_PCD
k141_2297_2	29495.EA26_05875	1.32e-114	333.0	COG1136@1|root,COG1136@2|Bacteria,1MVSQ@1224|Proteobacteria,1RMWK@1236|Gammaproteobacteria,1XTZP@135623|Vibrionales	135623|Vibrionales	V	Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner	lolD	GO:0003674,GO:0003824,GO:0005215,GO:0006810,GO:0008150,GO:0015399,GO:0015405,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0042623,GO:0042626,GO:0043492,GO:0051179,GO:0051234,GO:0055085	-	ko:K09810	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.125	-	-	ABC_tran
k141_2297_3	1517681.HW45_22095	6.05e-188	533.0	COG4591@1|root,COG4591@2|Bacteria,1MVV7@1224|Proteobacteria,1RMP9@1236|Gammaproteobacteria,1XSMT@135623|Vibrionales	135623|Vibrionales	M	COG4591 ABC-type transport system, involved in lipoprotein release, permease component	lolC	-	-	ko:K09808	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125	-	-	FtsX,MacB_PCD
k141_2297_4	675815.VOA_002222	1.41e-74	229.0	2CHGH@1|root,32S61@2|Bacteria,1MZN3@1224|Proteobacteria,1S9S8@1236|Gammaproteobacteria,1XUJE@135623|Vibrionales	135623|Vibrionales	-	-	VV12079	-	-	-	-	-	-	-	-	-	-	-	-
k141_2297_5	1348635.BBJY01000013_gene1020	0.0	1823.0	COG1197@1|root,COG1197@2|Bacteria,1MUXG@1224|Proteobacteria,1RNCU@1236|Gammaproteobacteria,1XSMS@135623|Vibrionales	135623|Vibrionales	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
k141_2297_6	675815.VOA_002224	9.82e-87	265.0	2EC19@1|root,3360G@2|Bacteria,1N87W@1224|Proteobacteria,1S7E3@1236|Gammaproteobacteria,1XSJF@135623|Vibrionales	135623|Vibrionales	S	Peptidoglycan-binding protein, CsiV	pgs1	-	-	-	-	-	-	-	-	-	-	-	CsiV
k141_2297_7	55601.VANGNB10_cI1714c	1.11e-269	743.0	COG1252@1|root,COG1252@2|Bacteria,1MX96@1224|Proteobacteria,1RM9I@1236|Gammaproteobacteria,1XTJK@135623|Vibrionales	135623|Vibrionales	C	COG1252 NADH dehydrogenase, FAD-containing subunit	ndh	-	1.6.99.3	ko:K03885	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
k141_2297_8	1205908.AKXW01000108_gene1180	3.16e-101	296.0	COG3150@1|root,COG3150@2|Bacteria,1NV1Y@1224|Proteobacteria,1RPQX@1236|Gammaproteobacteria,1XUBH@135623|Vibrionales	135623|Vibrionales	S	Belongs to the UPF0227 family	ycfP	-	-	ko:K07000	-	-	-	-	ko00000	-	-	-	UPF0227
k141_2297_9	1348635.BBJY01000013_gene1025	2.93e-94	286.0	COG0510@1|root,COG0510@2|Bacteria,1MURU@1224|Proteobacteria,1RNUN@1236|Gammaproteobacteria,1XTBI@135623|Vibrionales	135623|Vibrionales	M	choline kinase involved in LPS biosynthesis	thiK	-	-	-	-	-	-	-	-	-	-	-	APH,Choline_kinase
k141_2297_10	1280001.BAOA01000203_gene3478	1.35e-108	316.0	COG3417@1|root,COG3417@2|Bacteria,1RA6V@1224|Proteobacteria,1S30E@1236|Gammaproteobacteria,1XUJ6@135623|Vibrionales	135623|Vibrionales	M	Collagen-binding surface adhesin SpaP (Antigen I II family)	lpoB	-	-	ko:K07337	-	-	-	-	ko00000	-	-	-	LpoB
k141_2297_11	675815.VOA_002232	3.68e-31	114.0	COG5633@1|root,COG5633@2|Bacteria,1N0YQ@1224|Proteobacteria,1S20S@1236|Gammaproteobacteria,1XXI4@135623|Vibrionales	135623|Vibrionales	S	periplasmic lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	DUF1425
k141_2297_12	870967.VIS19158_00175	5.67e-172	498.0	COG3014@1|root,COG3014@2|Bacteria,1PD4S@1224|Proteobacteria,1RQ8Y@1236|Gammaproteobacteria,1XUG4@135623|Vibrionales	135623|Vibrionales	S	protein conserved in bacteria	-	-	-	ko:K09859	-	-	-	-	ko00000	-	-	-	-
k141_2297_14	675813.VIB_001631	1.45e-215	602.0	COG4006@1|root,COG4006@2|Bacteria,1RFA6@1224|Proteobacteria,1S6RM@1236|Gammaproteobacteria,1XU5U@135623|Vibrionales	135623|Vibrionales	S	Domain of unknown function (DUF1887)	VV2376	-	-	-	-	-	-	-	-	-	-	-	DUF1887
k141_2297_15	55601.VANGNB10_cI1723c	7.15e-161	455.0	COG2186@1|root,COG2186@2|Bacteria,1MW7M@1224|Proteobacteria,1RMRE@1236|Gammaproteobacteria,1XTXB@135623|Vibrionales	135623|Vibrionales	K	Multifunctional regulator of fatty acid metabolism	fadR	GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010563,GO:0010565,GO:0010605,GO:0010629,GO:0019216,GO:0019217,GO:0019219,GO:0019220,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045833,GO:0045892,GO:0045934,GO:0045936,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0051171,GO:0051172,GO:0051174,GO:0051252,GO:0051253,GO:0060255,GO:0062012,GO:0065007,GO:0071071,GO:0071072,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1903725,GO:1903726,GO:1990837,GO:2000112,GO:2000113,GO:2001141	-	ko:K03603	-	-	-	-	ko00000,ko03000	-	-	-	FadR_C,GntR
k141_2297_16	675815.VOA_002238	2.85e-291	806.0	COG3067@1|root,COG3067@2|Bacteria,1MV0F@1224|Proteobacteria,1RPE3@1236|Gammaproteobacteria,1XT42@135623|Vibrionales	135623|Vibrionales	P	) H( ) antiporter that extrudes sodium in exchange for external protons	nhaB	GO:0003674,GO:0005215,GO:0005451,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008150,GO:0008324,GO:0015075,GO:0015077,GO:0015078,GO:0015081,GO:0015291,GO:0015297,GO:0015298,GO:0015299,GO:0015318,GO:0015385,GO:0015491,GO:0015672,GO:0016020,GO:0022804,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0035725,GO:0044464,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:0099516,GO:1902600	-	ko:K03314	-	-	-	-	ko00000,ko02000	2.A.34.1	-	-	NhaB
k141_2297_17	223926.28807066	4.38e-81	244.0	COG1495@1|root,COG1495@2|Bacteria,1RIJE@1224|Proteobacteria,1S6WD@1236|Gammaproteobacteria,1XV2K@135623|Vibrionales	135623|Vibrionales	C	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein	dsbB	GO:0006457,GO:0008150,GO:0009987	-	ko:K03611	-	-	-	-	ko00000,ko03110	5.A.2.1	-	-	DsbB
k141_2297_18	675814.VIC_001596	0.0	1243.0	COG1674@1|root,COG1674@2|Bacteria,1MVPI@1224|Proteobacteria,1RM9A@1236|Gammaproteobacteria,1XUE7@135623|Vibrionales	135623|Vibrionales	D	COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins	ftsK	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
k141_2297_20	1280001.BAOA01000027_gene4829	1.53e-191	536.0	COG0583@1|root,COG0583@2|Bacteria,1MU8N@1224|Proteobacteria,1RN7T@1236|Gammaproteobacteria,1XTGJ@135623|Vibrionales	135623|Vibrionales	K	Transcriptional regulator	cysB	-	-	ko:K13634	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,LysR_substrate
k141_2297_21	243277.VC_1909	4.24e-116	340.0	28HXC@1|root,2Z831@2|Bacteria,1R415@1224|Proteobacteria,1RNDD@1236|Gammaproteobacteria,1XSGV@135623|Vibrionales	135623|Vibrionales	-	-	EBIG1844	-	-	-	-	-	-	-	-	-	-	-	-
k141_2297_22	29495.EA26_16015	1.38e-125	362.0	COG0284@1|root,COG0284@2|Bacteria,1MW2C@1224|Proteobacteria,1RNJR@1236|Gammaproteobacteria,1XUKK@135623|Vibrionales	135623|Vibrionales	F	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)	pyrF	GO:0003674,GO:0003824,GO:0004590,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase
k141_2297_23	345073.VC395_2027	9.64e-230	638.0	COG2956@1|root,COG2956@2|Bacteria,1MVDP@1224|Proteobacteria,1RP29@1236|Gammaproteobacteria,1XU1S@135623|Vibrionales	135623|Vibrionales	G	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane	lapB	-	-	ko:K19804	-	-	-	-	ko00000	-	-	-	TPR_16,TPR_19,TPR_7,TPR_8
k141_2297_24	1219076.N646_1103	1e-26	100.0	COG3771@1|root,COG3771@2|Bacteria,1MZGX@1224|Proteobacteria,1S9X9@1236|Gammaproteobacteria,1XYIY@135623|Vibrionales	135623|Vibrionales	S	Involved in the assembly of lipopolysaccharide (LPS)	lapA	-	-	ko:K08992	-	-	-	-	ko00000	-	-	-	LapA_dom
k141_2297_25	1280001.BAOA01000086_gene3537	3.17e-58	180.0	COG0776@1|root,COG0776@2|Bacteria,1MZ7M@1224|Proteobacteria,1S8XZ@1236|Gammaproteobacteria,1XXU9@135623|Vibrionales	135623|Vibrionales	K	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control	himD	GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009889,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2001141	-	ko:K05788	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
k141_2297_26	1238450.VIBNISOn1_600090	2.02e-115	345.0	COG0539@1|root,COG0539@2|Bacteria,1MVAV@1224|Proteobacteria,1RMFY@1236|Gammaproteobacteria,1XSTZ@135623|Vibrionales	135623|Vibrionales	J	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence	rpsA	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
k141_3971_2	1379281.AVAG01000040_gene806	1.63e-58	204.0	COG2114@1|root,COG4252@1|root,COG2114@2|Bacteria,COG4252@2|Bacteria,1MV1V@1224|Proteobacteria,42N5S@68525|delta/epsilon subdivisions,2WIUS@28221|Deltaproteobacteria,2M92Z@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	SMART Adenylyl cyclase class-3 4 guanylyl cyclase	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	CHASE2,Guanylate_cyc
k141_1985_1	1265505.ATUG01000002_gene2174	8.48e-116	350.0	COG4231@1|root,COG4231@2|Bacteria,1MUKS@1224|Proteobacteria,42N44@68525|delta/epsilon subdivisions,2WKYE@28221|Deltaproteobacteria,2MHUM@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates	iorA-2	-	1.2.7.8	ko:K00179	-	-	-	-	br01601,ko00000,ko01000	-	-	-	Fer4,POR_N,TPP_enzyme_C
k141_2868_2	1232437.KL662047_gene5198	6.19e-47	153.0	COG0537@1|root,COG0537@2|Bacteria,1RDCJ@1224|Proteobacteria,42SEH@68525|delta/epsilon subdivisions,2WPB9@28221|Deltaproteobacteria,2MK78@213118|Desulfobacterales	28221|Deltaproteobacteria	FG	Scavenger mRNA decapping enzyme C-term binding	hinT	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	DcpS_C,HIT
k141_2868_3	653733.Selin_1204	1.79e-77	247.0	COG1979@1|root,COG1979@2|Bacteria	2|Bacteria	C	1-butanol biosynthetic process	-	-	1.1.1.1	ko:K00001,ko:K00100,ko:K08325,ko:K19955	ko00010,ko00071,ko00350,ko00625,ko00626,ko00640,ko00650,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00640,map00650,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R02528,R03544,R03545,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC00739,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	Fe-ADH
k141_2555_1	1122201.AUAZ01000004_gene3391	1.08e-124	363.0	COG2378@1|root,COG2378@2|Bacteria,1MX81@1224|Proteobacteria,1RMSD@1236|Gammaproteobacteria,46755@72275|Alteromonadaceae	1236|Gammaproteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	WYL
k141_5244_2	675813.VIB_001592	3.14e-215	597.0	COG0180@1|root,COG0180@2|Bacteria,1MV4T@1224|Proteobacteria,1RNDC@1236|Gammaproteobacteria,1XSTM@135623|Vibrionales	135623|Vibrionales	J	Belongs to the class-I aminoacyl-tRNA synthetase family	-	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
k141_5244_3	1280001.BAOA01000022_gene556	2.5e-29	105.0	28R9G@1|root,2ZDP4@2|Bacteria,1P9ZB@1224|Proteobacteria,1SUFH@1236|Gammaproteobacteria,1XZ21@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_3373_4	1128398.Curi_c05390	1.91e-23	93.6	2DMI0@1|root,32UH1@2|Bacteria,1VF21@1239|Firmicutes,24VTB@186801|Clostridia	186801|Clostridia	S	Domain of unknown function (DUF4282)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4282
k141_3373_5	234267.Acid_0019	7.72e-62	229.0	2EY4D@1|root,33RD9@2|Bacteria,3Y6DM@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_3373_6	293826.Amet_3753	5.78e-31	129.0	COG0834@1|root,COG2199@1|root,COG2206@1|root,COG0834@2|Bacteria,COG2199@2|Bacteria,COG2206@2|Bacteria,1V6WM@1239|Firmicutes,24FPG@186801|Clostridia,36USB@31979|Clostridiaceae	186801|Clostridia	T	metal-dependent phosphohydrolase, HD sub domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,HAMP,HD,HD_5,PAS,PAS_4,PAS_8,PAS_9,dCache_1
k141_3373_7	266117.Rxyl_1295	3.04e-78	268.0	COG1404@1|root,COG3485@1|root,COG1404@2|Bacteria,COG3485@2|Bacteria,2GJYH@201174|Actinobacteria,4CS04@84995|Rubrobacteria	84995|Rubrobacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
k141_3373_8	1345695.CLSA_c19830	5.97e-230	684.0	2EYM2@1|root,33RUP@2|Bacteria,1VRT7@1239|Firmicutes,24CFI@186801|Clostridia,36FKY@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_3373_9	1415774.U728_614	1.88e-264	744.0	COG2345@1|root,COG2345@2|Bacteria,1V0U6@1239|Firmicutes,24AX6@186801|Clostridia,36FKQ@31979|Clostridiaceae	186801|Clostridia	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	SWIM
k141_3373_10	1345695.CLSA_c19850	6.22e-187	538.0	COG3344@1|root,COG3344@2|Bacteria,1UZGS@1239|Firmicutes,247Z6@186801|Clostridia,36GER@31979|Clostridiaceae	186801|Clostridia	L	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	RVT_1
k141_3373_11	1511.CLOST_2410	5.1e-142	409.0	COG1879@1|root,COG1879@2|Bacteria,1TQ1B@1239|Firmicutes,247K8@186801|Clostridia,25QU7@186804|Peptostreptococcaceae	186801|Clostridia	G	Periplasmic binding protein domain	rbsB	-	-	ko:K10439	ko02010,ko02030,map02010,map02030	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	Peripla_BP_4
k141_3373_12	1301100.HG529275_gene1623	1.75e-126	371.0	COG1172@1|root,COG1172@2|Bacteria,1TP72@1239|Firmicutes,249FA@186801|Clostridia,36DTM@31979|Clostridiaceae	186801|Clostridia	G	Belongs to the binding-protein-dependent transport system permease family	rbsC	-	-	ko:K10440	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	BPD_transp_2
k141_3373_13	469618.FVAG_00841	4.89e-194	557.0	COG1129@1|root,COG1129@2|Bacteria,37997@32066|Fusobacteria	32066|Fusobacteria	G	Part of the ABC transporter complex MglABC involved in galactose methyl galactoside import. Responsible for energy coupling to the transport system	rbsA	-	3.6.3.17	ko:K10441	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	ABC_tran
k141_3373_14	935836.JAEL01000019_gene879	8.24e-43	144.0	COG1869@1|root,COG1869@2|Bacteria,1VA2V@1239|Firmicutes,4HIFW@91061|Bacilli,1ZGYM@1386|Bacillus	91061|Bacilli	G	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose	rbsD	GO:0003674,GO:0003824,GO:0005215,GO:0006810,GO:0008150,GO:0008643,GO:0015144,GO:0015145,GO:0015146,GO:0015399,GO:0015405,GO:0015407,GO:0015591,GO:0015608,GO:0015611,GO:0015749,GO:0015750,GO:0015752,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0034219,GO:0042623,GO:0042626,GO:0043211,GO:0043492,GO:0051119,GO:0051179,GO:0051234,GO:0055085,GO:0071702	5.4.99.62	ko:K06726	ko02010,map02010	-	R08247	RC02247	ko00000,ko00001,ko01000	-	-	-	RbsD_FucU
k141_3373_15	469616.FMAG_02323	8.21e-89	274.0	COG0524@1|root,COG0524@2|Bacteria,3791K@32066|Fusobacteria	32066|Fusobacteria	H	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway	rbsK	-	2.7.1.15	ko:K00852	ko00030,map00030	-	R01051,R02750	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
k141_3373_16	580327.Tthe_1727	6.25e-93	288.0	COG1609@1|root,COG1609@2|Bacteria,1TQ7K@1239|Firmicutes,247M2@186801|Clostridia,42EQH@68295|Thermoanaerobacterales	186801|Clostridia	K	Periplasmic binding protein LacI transcriptional regulator	rbsR	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_1,Peripla_BP_3
k141_3373_17	86416.Clopa_0452	8.07e-89	274.0	COG2378@1|root,COG2378@2|Bacteria,1TS78@1239|Firmicutes,25C7I@186801|Clostridia,36E2Q@31979|Clostridiaceae	186801|Clostridia	K	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_11,WYL
k141_3373_18	272563.CD630_10070	2.25e-39	132.0	COG3708@1|root,COG3708@2|Bacteria,1VFMZ@1239|Firmicutes,24RKD@186801|Clostridia,25TVT@186804|Peptostreptococcaceae	186801|Clostridia	K	Putative zinc ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	Cass2,Zn_ribbon_2
k141_3373_19	111780.Sta7437_1135	5.35e-13	72.0	2DIHB@1|root,303AH@2|Bacteria,1GKIS@1117|Cyanobacteria,3VNCG@52604|Pleurocapsales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_3373_20	1248232.BANQ01000120_gene329	3.93e-241	674.0	COG0733@1|root,COG0733@2|Bacteria,1MUZJ@1224|Proteobacteria,1RPCT@1236|Gammaproteobacteria,1XT5X@135623|Vibrionales	135623|Vibrionales	S	COG0733 Na -dependent transporters of the SNF family	-	-	-	ko:K03308	-	-	-	-	ko00000	2.A.22.4,2.A.22.5	-	-	SNF
k141_3373_21	1216932.CM240_3303	1.63e-26	123.0	COG0457@1|root,COG2199@1|root,COG0457@2|Bacteria,COG2199@2|Bacteria,1VQTU@1239|Firmicutes,24D8M@186801|Clostridia,36GZE@31979|Clostridiaceae	186801|Clostridia	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
k141_3373_22	610130.Closa_2758	1.86e-187	543.0	COG2199@1|root,COG2199@2|Bacteria,1UZF7@1239|Firmicutes,25E5Q@186801|Clostridia	186801|Clostridia	T	Diguanylate cyclase, GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,dCache_1
k141_3373_24	617140.AJZE01000093_gene2472	8.9e-53	173.0	COG1051@1|root,COG1051@2|Bacteria,1RB8R@1224|Proteobacteria,1S1A6@1236|Gammaproteobacteria,1XSJ6@135623|Vibrionales	135623|Vibrionales	F	COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
k141_3373_25	1410653.JHVC01000003_gene3821	2.5e-189	535.0	COG1453@1|root,COG1453@2|Bacteria,1TQ5N@1239|Firmicutes,247SD@186801|Clostridia,36F1U@31979|Clostridiaceae	186801|Clostridia	C	aldo keto reductase	-	-	-	ko:K07079	-	-	-	-	ko00000	-	-	-	Aldo_ket_red,Fer4_17
k141_3373_26	1123009.AUID01000016_gene22	7.2e-195	549.0	COG1915@1|root,COG1915@2|Bacteria,1UZ9T@1239|Firmicutes,24CGV@186801|Clostridia,26A2V@186813|unclassified Clostridiales	186801|Clostridia	S	PFAM LOR SDH bifunctional enzyme conserved region	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_3373_27	1123009.AUID01000016_gene21	4.96e-210	586.0	COG1915@1|root,COG1915@2|Bacteria,1TT91@1239|Firmicutes,24A6C@186801|Clostridia,268BA@186813|unclassified Clostridiales	186801|Clostridia	S	PFAM LOR SDH bifunctional enzyme conserved region	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_3373_28	1443125.Z962_11630	2.41e-100	302.0	COG0535@1|root,COG0535@2|Bacteria,1V647@1239|Firmicutes,25GQS@186801|Clostridia,36KPP@31979|Clostridiaceae	186801|Clostridia	S	radical SAM protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_3373_29	526218.Sterm_1642	1.89e-150	441.0	COG0635@1|root,COG0635@2|Bacteria,378ZR@32066|Fusobacteria	2|Bacteria	H	Involved in the biosynthesis of porphyrin-containing compound	hemN1	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
k141_3373_30	1443125.Z962_05865	2.76e-135	390.0	COG3119@1|root,COG3119@2|Bacteria,1TVD7@1239|Firmicutes,24D8H@186801|Clostridia,36IFG@31979|Clostridiaceae	186801|Clostridia	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
k141_3373_31	1443125.Z962_05870	2.33e-123	367.0	COG0189@1|root,COG0189@2|Bacteria,1V6GR@1239|Firmicutes,24FXH@186801|Clostridia,36N13@31979|Clostridiaceae	186801|Clostridia	HJ	ligase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_3373_32	1227349.C170_01339	2.99e-63	208.0	COG4886@1|root,COG4886@2|Bacteria,1UZCK@1239|Firmicutes,4I6FE@91061|Bacilli,26SQ3@186822|Paenibacillaceae	91061|Bacilli	S	Leucine Rich repeat	-	-	-	-	-	-	-	-	-	-	-	-	LRR_6
k141_3373_33	1118059.CAHC01000001_gene625	3.77e-289	826.0	COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,247TD@186801|Clostridia,3WCC2@538999|Clostridiales incertae sedis	186801|Clostridia	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695,ko:K03696	ko01100,ko04213,map01100,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
k141_3373_34	1499684.CCNP01000018_gene1215	5.85e-26	100.0	COG1942@1|root,COG1942@2|Bacteria,1VA6U@1239|Firmicutes,24MXT@186801|Clostridia,36KV1@31979|Clostridiaceae	186801|Clostridia	S	Domain of unknown function (DUF1904)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1904
k141_3373_36	1123290.AUDQ01000001_gene2896	5.58e-228	645.0	COG1292@1|root,COG1292@2|Bacteria,1TR5F@1239|Firmicutes,4HBSH@91061|Bacilli,26GSI@186818|Planococcaceae	91061|Bacilli	M	Belongs to the BCCT transporter (TC 2.A.15) family	-	-	-	-	-	-	-	-	-	-	-	-	BCCT
k141_3373_37	1190606.AJYG01000011_gene3808	3.72e-38	134.0	COG0350@1|root,COG0350@2|Bacteria,1N2YQ@1224|Proteobacteria,1S68H@1236|Gammaproteobacteria,1XX26@135623|Vibrionales	135623|Vibrionales	H	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated	ada	-	2.1.1.63	ko:K10778	-	-	-	-	ko00000,ko01000,ko03000,ko03400	-	-	-	DNA_binding_1,HTH_18
k141_3373_38	373903.Hore_05190	1.06e-185	532.0	COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,247YX@186801|Clostridia,3WAZ5@53433|Halanaerobiales	186801|Clostridia	V	efflux protein, MATE family	-	-	-	-	-	-	-	-	-	-	-	-	MatE
k141_3373_39	411463.EUBVEN_00797	1.87e-108	324.0	COG1234@1|root,COG1234@2|Bacteria,1TRGP@1239|Firmicutes,248EQ@186801|Clostridia,25VP6@186806|Eubacteriaceae	186801|Clostridia	J	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA	rnz	-	3.1.26.11	ko:K00784	ko03013,map03013	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	Lactamase_B_2
k141_3373_40	536232.CLM_2451	4.53e-186	535.0	COG0579@1|root,COG0579@2|Bacteria,1TRDH@1239|Firmicutes,248IK@186801|Clostridia,36DNW@31979|Clostridiaceae	186801|Clostridia	C	FAD dependent oxidoreductase	-	-	1.1.5.3	ko:K00111	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	DAO,Fer2_BFD,NAD_binding_8
k141_3373_41	199310.c5113	4e-52	168.0	COG2824@1|root,COG2824@2|Bacteria,1RGUU@1224|Proteobacteria,1S60W@1236|Gammaproteobacteria,3XPRW@561|Escherichia	1236|Gammaproteobacteria	P	PhnA Zinc-Ribbon	phnA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K06193	ko01120,map01120	-	-	-	ko00000	-	-	-	PhnA,PhnA_Zn_Ribbon
k141_3373_43	357809.Cphy_1504	7.29e-158	459.0	2DB7K@1|root,2Z7MK@2|Bacteria,1TQ79@1239|Firmicutes,2489P@186801|Clostridia,21YG7@1506553|Lachnoclostridium	186801|Clostridia	S	Protein of unknown function (DUF1576)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1576
k141_3373_44	1347392.CCEZ01000008_gene2158	3.69e-145	413.0	COG0708@1|root,COG0708@2|Bacteria,1TPFB@1239|Firmicutes,24849@186801|Clostridia,36E73@31979|Clostridiaceae	186801|Clostridia	L	exodeoxyribonuclease III	xth	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
k141_3373_45	318464.IO99_00930	2.41e-66	238.0	COG0840@1|root,COG0840@2|Bacteria,1TP5A@1239|Firmicutes,247S3@186801|Clostridia,36EQK@31979|Clostridiaceae	186801|Clostridia	NT	chemotaxis	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal,dCache_1
k141_3373_47	1347392.CCEZ01000049_gene1387	3.67e-75	232.0	COG0522@1|root,COG0522@2|Bacteria,1TR0J@1239|Firmicutes,248Y5@186801|Clostridia,36DKK@31979|Clostridiaceae	186801|Clostridia	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	-	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
k141_1366_12	536232.CLM_2466	1.27e-29	107.0	COG5566@1|root,COG5566@2|Bacteria,1VEZS@1239|Firmicutes,24QVB@186801|Clostridia,36MRC@31979|Clostridiaceae	186801|Clostridia	S	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Mor
k141_1366_13	1123009.AUID01000022_gene1388	2.36e-266	736.0	COG2202@1|root,COG5001@1|root,COG2202@2|Bacteria,COG5001@2|Bacteria	2|Bacteria	T	cyclic-guanylate-specific phosphodiesterase activity	-	-	3.1.3.15	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03013	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	GGDEF,HATPase_c,HTH_3,PAS,PAS_3,PAS_4,PAS_9
k141_1366_14	1540257.JQMW01000009_gene3884	3.06e-127	370.0	COG0384@1|root,COG0384@2|Bacteria,1TPPX@1239|Firmicutes,247ZD@186801|Clostridia,36U61@31979|Clostridiaceae	186801|Clostridia	S	Phenazine biosynthesis-like protein	-	-	5.3.3.17	ko:K06998	ko00405,ko01130,ko02024,map00405,map01130,map02024	M00835	-	-	ko00000,ko00001,ko00002,ko01000	-	-	-	PhzC-PhzF
k141_1366_18	1033810.HLPCO_000248	1.76e-66	211.0	COG0745@1|root,COG0745@2|Bacteria,2NRZI@2323|unclassified Bacteria	2|Bacteria	KT	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
k141_1366_20	329726.AM1_1311	3.72e-82	265.0	2AVMD@1|root,2ZA6Y@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_1366_21	1405.DJ92_3425	1.48e-47	175.0	COG3104@1|root,COG3104@2|Bacteria,1UHSN@1239|Firmicutes,4IS8A@91061|Bacilli,1ZS2I@1386|Bacillus	91061|Bacilli	E	Transmembrane secretion effector	lmrP	-	-	ko:K08152	-	-	-	-	ko00000,ko02000	2.A.1.2	-	-	MFS_1,Sugar_tr
k141_1366_22	445973.CLOBAR_02396	3.21e-48	157.0	COG2824@1|root,COG2824@2|Bacteria,1V6NA@1239|Firmicutes,24J9K@186801|Clostridia,25TK9@186804|Peptostreptococcaceae	186801|Clostridia	P	PhnA Zinc-Ribbon	phnA	-	-	ko:K06193	ko01120,map01120	-	-	-	ko00000	-	-	-	PhnA,PhnA_Zn_Ribbon
k141_1366_23	1268240.ATFI01000018_gene22	4.03e-113	332.0	COG4422@1|root,COG4422@2|Bacteria,4NJKJ@976|Bacteroidetes,2FNM4@200643|Bacteroidia,4ANC0@815|Bacteroidaceae	976|Bacteroidetes	S	COG4422 Bacteriophage protein gp37	-	-	-	-	-	-	-	-	-	-	-	-	DUF5131
k141_349_2	247490.KSU1_C0393	3.8e-18	82.8	COG0071@1|root,COG0071@2|Bacteria,2J3XK@203682|Planctomycetes	203682|Planctomycetes	O	Hsp20/alpha crystallin family	-	-	-	-	-	-	-	-	-	-	-	-	HSP20
k141_349_3	1304885.AUEY01000031_gene48	0.0	1036.0	COG0466@1|root,COG0466@2|Bacteria,1MUV2@1224|Proteobacteria,42M9W@68525|delta/epsilon subdivisions,2WJ29@28221|Deltaproteobacteria,2MHRD@213118|Desulfobacterales	28221|Deltaproteobacteria	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	-	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
k141_349_4	879212.DespoDRAFT_00065	2.41e-25	102.0	COG0797@1|root,COG0797@2|Bacteria,1MZ8S@1224|Proteobacteria,42PQF@68525|delta/epsilon subdivisions,2WMCA@28221|Deltaproteobacteria,2MHV7@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides	rlpA	-	-	ko:K03642	-	-	-	-	ko00000	-	-	-	DPBB_1,SPOR
k141_23_1	1265505.ATUG01000001_gene4402	8.62e-189	541.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WJF9@28221|Deltaproteobacteria,2MHRZ@213118|Desulfobacterales	28221|Deltaproteobacteria	T	response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
k141_23_2	1114970.PSF113_3234	2.39e-10	60.8	COG2202@1|root,COG4191@1|root,COG2202@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,1RP53@1236|Gammaproteobacteria,1YNP5@136843|Pseudomonas fluorescens group	1236|Gammaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,PAS,PAS_3,PAS_4,Response_reg
k141_1367_1	589865.DaAHT2_1639	2.38e-11	69.3	COG4105@1|root,COG4105@2|Bacteria,1MVS5@1224|Proteobacteria,42RV8@68525|delta/epsilon subdivisions,2WKU0@28221|Deltaproteobacteria,2MJ58@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamD	-	-	ko:K05807	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	YfiO
k141_1367_2	1304885.AUEY01000050_gene1194	1.1e-11	64.3	COG0492@1|root,COG0492@2|Bacteria,1MV15@1224|Proteobacteria,42MHR@68525|delta/epsilon subdivisions,2WIY8@28221|Deltaproteobacteria,2MJC5@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Pyridine nucleotide-disulphide oxidoreductase	trxB	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
k141_24_1	243277.VC_2736	3.38e-104	309.0	COG1281@1|root,COG1281@2|Bacteria,1MUMU@1224|Proteobacteria,1RMP3@1236|Gammaproteobacteria,1XTZA@135623|Vibrionales	135623|Vibrionales	O	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress	hslO	-	-	ko:K04083	-	-	-	-	ko00000,ko03110	-	-	-	HSP33
k141_25_2	1121405.dsmv_3053	2.5e-75	255.0	COG1197@1|root,COG1197@2|Bacteria,1MUXG@1224|Proteobacteria,42N8X@68525|delta/epsilon subdivisions,2WIVR@28221|Deltaproteobacteria,2MI3P@213118|Desulfobacterales	28221|Deltaproteobacteria	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
k141_350_2	592026.GCWU0000282_002435	2.1e-14	84.7	28J75@1|root,2Z92N@2|Bacteria,1UIFS@1239|Firmicutes,25EM7@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_26_1	66377.JOBH01000030_gene3526	9.25e-06	49.3	COG0673@1|root,COG0673@2|Bacteria,2GJCY@201174|Actinobacteria	201174|Actinobacteria	G	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose)	-	-	1.1.1.18,1.1.1.369	ko:K00010	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	-	R01183,R09951	RC00182	ko00000,ko00001,ko01000	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
k141_26_2	865861.AZSU01000001_gene347	6.65e-69	219.0	COG1172@1|root,COG1172@2|Bacteria,1TP72@1239|Firmicutes,249FA@186801|Clostridia,36DTM@31979|Clostridiaceae	186801|Clostridia	G	Belongs to the binding-protein-dependent transport system permease family	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_2
k141_1719_3	293826.Amet_2616	4.08e-229	651.0	COG1961@1|root,COG1961@2|Bacteria,1TS5B@1239|Firmicutes,24BET@186801|Clostridia,36ET1@31979|Clostridiaceae	186801|Clostridia	L	Resolvase, N terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
k141_1371_1	553973.CLOHYLEM_05929	5.55e-41	144.0	COG1063@1|root,COG1063@2|Bacteria,1TPWP@1239|Firmicutes,248Z5@186801|Clostridia,21ZK2@1506553|Lachnoclostridium	186801|Clostridia	E	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
k141_696_1	945543.VIBR0546_02675	4.89e-18	89.0	COG3209@1|root,COG3209@2|Bacteria,1PDT2@1224|Proteobacteria,1TEF8@1236|Gammaproteobacteria,1XZDG@135623|Vibrionales	135623|Vibrionales	M	COG3209 Rhs family protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_1720_1	1565314.OA34_11865	1.63e-14	79.7	COG1344@1|root,COG1344@2|Bacteria,1MV1N@1224|Proteobacteria,42MX8@68525|delta/epsilon subdivisions,2YN00@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella	flaB	GO:0001539,GO:0005575,GO:0005576,GO:0005623,GO:0006928,GO:0008150,GO:0009288,GO:0009987,GO:0040011,GO:0042995,GO:0043226,GO:0043228,GO:0044464,GO:0048870,GO:0051179,GO:0051674,GO:0071973,GO:0071978,GO:0097588	-	ko:K02406	ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flagellin_C,Flagellin_IN,Flagellin_N
k141_1721_1	879212.DespoDRAFT_03732	3.85e-91	272.0	COG1943@1|root,COG1943@2|Bacteria,1P19I@1224|Proteobacteria,42PP3@68525|delta/epsilon subdivisions,2WK0G@28221|Deltaproteobacteria,2MJPT@213118|Desulfobacterales	28221|Deltaproteobacteria	L	Transposase IS200 like	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
k141_28_1	177437.HRM2_30920	4.18e-68	228.0	COG0455@1|root,COG0455@2|Bacteria,1R8IW@1224|Proteobacteria,42PF7@68525|delta/epsilon subdivisions,2WMTH@28221|Deltaproteobacteria,2MJB2@213118|Desulfobacterales	28221|Deltaproteobacteria	D	Cellulose biosynthesis protein BcsQ	-	-	-	-	-	-	-	-	-	-	-	-	AAA_31,CbiA,ParA
k141_1372_1	1293054.HSACCH_02552	2.63e-28	110.0	COG1212@1|root,COG1212@2|Bacteria,1TQU3@1239|Firmicutes,24H2B@186801|Clostridia,3WAKF@53433|Halanaerobiales	186801|Clostridia	M	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria	kdsB	-	2.7.7.38	ko:K00979	ko00540,ko01100,map00540,map01100	M00063	R03351,R11396	RC00152,RC00910	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_3
k141_1372_2	1121403.AUCV01000013_gene3971	1.56e-53	182.0	COG0561@1|root,COG0561@2|Bacteria,1QJIT@1224|Proteobacteria,42PG7@68525|delta/epsilon subdivisions,2WKZW@28221|Deltaproteobacteria,2MHTG@213118|Desulfobacterales	28221|Deltaproteobacteria	S	haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
k141_3085_1	933262.AXAM01000013_gene1310	1.91e-197	583.0	COG1026@1|root,COG1026@2|Bacteria,1MVDJ@1224|Proteobacteria,42MRG@68525|delta/epsilon subdivisions,2WJ5Q@28221|Deltaproteobacteria,2MINB@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Peptidase M16C associated	PREP	-	-	ko:K06972	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M16C_assoc,Peptidase_M16,Peptidase_M16_C
k141_1722_1	1499683.CCFF01000017_gene1655	5.96e-13	63.9	2BSZ9@1|root,32N36@2|Bacteria,1UUPJ@1239|Firmicutes,257CX@186801|Clostridia,36TEE@31979|Clostridiaceae	186801|Clostridia	S	Virus attachment protein p12 family	-	-	-	-	-	-	-	-	-	-	-	-	P12
k141_3757_1	983545.Glaag_3319	8.49e-42	147.0	COG0451@1|root,COG0451@2|Bacteria,1MU7J@1224|Proteobacteria,1RPTA@1236|Gammaproteobacteria,464JQ@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	COG0451 Nucleoside-diphosphate-sugar epimerases	lspL	-	5.1.3.25,5.1.3.6	ko:K08679,ko:K17947	ko00520,ko00523,ko01100,ko01130,map00520,map00523,map01100,map01130	-	R01385,R10279	RC00289	ko00000,ko00001,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
k141_3757_2	1348635.BBJY01000002_gene3533	4.19e-154	434.0	COG0813@1|root,COG0813@2|Bacteria,1MUW6@1224|Proteobacteria,1RMMA@1236|Gammaproteobacteria,1XUQM@135623|Vibrionales	135623|Vibrionales	F	phosphorylase	deoD	GO:0003674,GO:0003824,GO:0004731,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0034641,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:1901360	2.4.2.1	ko:K03784	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244	RC00033,RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
k141_3757_3	1280001.BAOA01000059_gene2256	3.23e-109	322.0	COG0274@1|root,COG0274@2|Bacteria,1N8AG@1224|Proteobacteria,1RPTS@1236|Gammaproteobacteria,1XTNE@135623|Vibrionales	135623|Vibrionales	F	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate	deoC	GO:0003674,GO:0003824,GO:0004139,GO:0005975,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009262,GO:0009264,GO:0009987,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576	4.1.2.4	ko:K01619	ko00030,map00030	-	R01066	RC00436,RC00437	ko00000,ko00001,ko01000	-	-	-	DeoC
k141_3757_4	675816.VIA_003813	4.58e-232	647.0	COG1972@1|root,COG1972@2|Bacteria,1MXXX@1224|Proteobacteria,1RMBX@1236|Gammaproteobacteria,1XSKX@135623|Vibrionales	135623|Vibrionales	U	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family	-	-	-	ko:K03317	-	-	-	-	ko00000	2.A.41	-	-	Gate,Nucleos_tra2_C,Nucleos_tra2_N
k141_3757_5	575788.VS_2465	6.98e-87	267.0	COG0084@1|root,COG0084@2|Bacteria,1MW5C@1224|Proteobacteria,1RP5T@1236|Gammaproteobacteria,1XUGD@135623|Vibrionales	135623|Vibrionales	L	COG0084 Mg-dependent DNase	yjjV	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
k141_3757_6	55601.VANGNB10_cI2132c	4.68e-42	144.0	COG3022@1|root,COG3022@2|Bacteria,1MUAF@1224|Proteobacteria,1RMTD@1236|Gammaproteobacteria,1XUFU@135623|Vibrionales	135623|Vibrionales	S	Belongs to the UPF0246 family	yaaA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0033194,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:1901700	-	ko:K09861	-	-	-	-	ko00000	-	-	-	H2O2_YaaD
k141_1351_1	1219076.N646_1452	8.72e-125	369.0	COG0733@1|root,COG0733@2|Bacteria,1MUZJ@1224|Proteobacteria,1RPCT@1236|Gammaproteobacteria,1XT5X@135623|Vibrionales	135623|Vibrionales	S	COG0733 Na -dependent transporters of the SNF family	-	-	-	ko:K03308	-	-	-	-	ko00000	2.A.22.4,2.A.22.5	-	-	SNF
k141_2957_2	1123500.ATUU01000001_gene322	3.29e-81	254.0	COG4974@1|root,COG4974@2|Bacteria,1TQRG@1239|Firmicutes,4HAEX@91061|Bacilli,4AWH0@81850|Leuconostocaceae	91061|Bacilli	D	recombinase XerD	xerD	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
k141_2957_3	1121403.AUCV01000021_gene3604	3.9e-75	239.0	COG0006@1|root,COG0006@2|Bacteria,1MUZS@1224|Proteobacteria,42M1K@68525|delta/epsilon subdivisions,2WJ8E@28221|Deltaproteobacteria,2MIXX@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Creatinase/Prolidase N-terminal domain	pepQ	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Creatinase_N,Creatinase_N_2,Peptidase_M24,Peptidase_M24_C
k141_5305_1	1121451.DESAM_20034	1.54e-17	82.0	28I7K@1|root,2Z8AG@2|Bacteria,1PP1H@1224|Proteobacteria,42PGZ@68525|delta/epsilon subdivisions,2WKVY@28221|Deltaproteobacteria,2M7UV@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4815)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4815
k141_5305_2	1121451.DESAM_20027	4.53e-37	125.0	COG3311@1|root,COG3311@2|Bacteria,1N779@1224|Proteobacteria,42VDM@68525|delta/epsilon subdivisions,2WR6J@28221|Deltaproteobacteria,2MDKV@213115|Desulfovibrionales	28221|Deltaproteobacteria	L	TIGRFAM DNA binding domain protein, excisionase family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
k141_5305_3	1307761.L21SP2_2652	2.81e-265	732.0	COG0286@1|root,COG0286@2|Bacteria,2J6AA@203691|Spirochaetes	203691|Spirochaetes	V	type I restriction-modification system	hsdM	-	2.1.1.72	ko:K03427	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HsdM_N,N6_Mtase
k141_2639_1	436717.AOLE_01255	5.38e-06	53.9	COG5265@1|root,COG5265@2|Bacteria,1RGA5@1224|Proteobacteria,1SN9D@1236|Gammaproteobacteria,3NJEA@468|Moraxellaceae	1236|Gammaproteobacteria	P	ABC transporter transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
k141_2639_2	644282.Deba_0474	1.73e-138	430.0	COG1629@1|root,COG4771@2|Bacteria,1MX42@1224|Proteobacteria,42QI5@68525|delta/epsilon subdivisions	1224|Proteobacteria	P	TonB dependent receptor	frpB	-	-	ko:K02014,ko:K16087	-	-	-	-	ko00000,ko02000	1.B.14,1.B.14.2	-	-	Plug,TonB_dep_Rec
k141_2639_3	575788.VS_2666	1.05e-102	307.0	COG4822@1|root,COG4822@2|Bacteria,1QKXK@1224|Proteobacteria,1TJ3I@1236|Gammaproteobacteria,1Y0FK@135623|Vibrionales	135623|Vibrionales	H	Cobalt chelatase (CbiK)	-	-	4.99.1.3	ko:K02190	ko00860,ko01100,map00860,map01100	-	R05807	RC01012	ko00000,ko00001,ko01000	-	-	-	CbiK
k141_2958_1	1224318.DT73_04280	0.0	1001.0	COG0834@1|root,COG2206@1|root,COG3437@1|root,COG0834@2|Bacteria,COG2206@2|Bacteria,COG3437@2|Bacteria,1MV37@1224|Proteobacteria,1RM9C@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	COG0840 Methyl-accepting chemotaxis protein	-	-	-	-	-	-	-	-	-	-	-	-	HD_5,SBP_bac_3,dCache_1
k141_5307_1	1121405.dsmv_0274	1.44e-27	110.0	COG3528@1|root,COG3528@2|Bacteria,1R601@1224|Proteobacteria,42Q98@68525|delta/epsilon subdivisions,2WM5S@28221|Deltaproteobacteria,2MNQ0@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Uncharacterized protein conserved in bacteria (DUF2219)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2219
k141_5307_2	96561.Dole_2054	1.8e-160	465.0	COG1253@1|root,COG1253@2|Bacteria,1MV3P@1224|Proteobacteria,42N97@68525|delta/epsilon subdivisions,2WJV1@28221|Deltaproteobacteria,2MIHF@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Transporter associated domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,DUF21
k141_5307_3	667014.Thein_1237	2.96e-37	133.0	COG1396@1|root,COG1917@1|root,COG1396@2|Bacteria,COG1917@2|Bacteria	2|Bacteria	L	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,HTH_3,HTH_31
k141_2641_1	595494.Tola_1580	4.87e-54	175.0	COG4215@1|root,COG4215@2|Bacteria,1MY2N@1224|Proteobacteria,1RNYD@1236|Gammaproteobacteria,1Y47J@135624|Aeromonadales	135624|Aeromonadales	P	ABC transporter	-	-	-	ko:K10016	ko02010,map02010	M00225,M00226	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3.1	-	-	BPD_transp_1
k141_2641_2	1283284.AZUK01000001_gene159	5.67e-133	381.0	COG4160@1|root,COG4160@2|Bacteria,1MWI6@1224|Proteobacteria,1RPT1@1236|Gammaproteobacteria,1Y46G@135624|Aeromonadales	1236|Gammaproteobacteria	P	Binding-protein-dependent transport system inner membrane component	hisM	GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0015711,GO:0015849,GO:0016020,GO:0044464,GO:0046942,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944	-	ko:K10015	ko02010,map02010	M00225,M00226	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3.1	-	iAF1260.b2307,iAPECO1_1312.APECO1_4257,iB21_1397.B21_02192,iBWG_1329.BWG_2081,iE2348C_1286.E2348C_2447,iEC55989_1330.EC55989_2551,iECABU_c1320.ECABU_c26390,iECBD_1354.ECBD_1352,iECB_1328.ECB_02232,iECDH10B_1368.ECDH10B_2469,iECDH1ME8569_1439.ECDH1ME8569_2245,iECD_1391.ECD_02232,iECED1_1282.ECED1_2771,iECH74115_1262.ECH74115_3447,iECIAI1_1343.ECIAI1_2383,iECIAI39_1322.ECIAI39_2456,iECNA114_1301.ECNA114_2397,iECO103_1326.ECO103_2771,iECO111_1330.ECO111_3055,iECO26_1355.ECO26_3295,iECOK1_1307.ECOK1_2540,iECP_1309.ECP_2346,iECS88_1305.ECS88_2454,iECSE_1348.ECSE_2616,iECSF_1327.ECSF_2183,iECSP_1301.ECSP_3182,iECW_1372.ECW_m2496,iECs_1301.ECs3191,iEKO11_1354.EKO11_1458,iETEC_1333.ETEC_2443,iEcDH1_1363.EcDH1_1349,iEcE24377_1341.EcE24377A_2601,iEcSMS35_1347.EcSMS35_2463,iEcolC_1368.EcolC_1345,iG2583_1286.G2583_2844,iJO1366.b2307,iJR904.b2307,iLF82_1304.LF82_1007,iNRG857_1313.NRG857_11685,iSDY_1059.SDY_2506,iSFV_1184.SFV_2374,iSF_1195.SF2383,iSFxv_1172.SFxv_2628,iSSON_1240.SSON_2365,iS_1188.S2518,iSbBS512_1146.SbBS512_E2685,iUMN146_1321.UM146_05275,iUMNK88_1353.UMNK88_2858,iUTI89_1310.UTI89_C2591,iWFL_1372.ECW_m2496,iY75_1357.Y75_RS12100,ic_1306.c2849	BPD_transp_1
k141_2641_3	595494.Tola_1578	7.61e-154	435.0	COG4598@1|root,COG4598@2|Bacteria,1QTS2@1224|Proteobacteria,1RQYN@1236|Gammaproteobacteria,1Y3PP@135624|Aeromonadales	135624|Aeromonadales	E	ABC transporter	-	-	3.6.3.21	ko:K10017	ko02010,map02010	M00225,M00226	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.3.1	-	-	ABC_tran
k141_2641_4	243159.AFE_0551	8.54e-09	57.0	COG0388@1|root,COG0388@2|Bacteria,1MUUB@1224|Proteobacteria,1RNVZ@1236|Gammaproteobacteria,2NCQU@225057|Acidithiobacillales	225057|Acidithiobacillales	S	Carbon-nitrogen hydrolase	-	-	-	ko:K11206	-	-	-	-	ko00000,ko01000	-	-	-	CN_hydrolase
k141_2960_1	720555.BATR1942_06385	4.64e-74	229.0	COG1024@1|root,COG1024@2|Bacteria,1TRGW@1239|Firmicutes,4HBJK@91061|Bacilli	91061|Bacilli	I	Enoyl-CoA hydratase/isomerase	pksH	-	-	ko:K15312	-	-	-	-	ko00000,ko01008	-	-	-	ECH_1
k141_2642_1	1385935.N836_12625	5.7e-31	125.0	COG4773@1|root,COG4773@2|Bacteria,1G2N1@1117|Cyanobacteria,1HENZ@1150|Oscillatoriales	1117|Cyanobacteria	P	TonB dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	AMIN,Plug,TonB_dep_Rec
k141_5310_1	96561.Dole_2443	8.58e-109	327.0	COG0341@1|root,COG0341@2|Bacteria,1MU74@1224|Proteobacteria,42M2H@68525|delta/epsilon subdivisions,2WJ8I@28221|Deltaproteobacteria,2MI34@213118|Desulfobacterales	28221|Deltaproteobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secF	-	-	ko:K03074	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
k141_2961_1	1367847.JCM7686_2794	1.98e-26	113.0	COG3482@1|root,COG3482@2|Bacteria,1QG2J@1224|Proteobacteria,2TUJJ@28211|Alphaproteobacteria,2PW65@265|Paracoccus	28211|Alphaproteobacteria	S	TfuA-like protein	-	-	-	-	-	-	-	-	-	-	-	-	TfuA
k141_4357_3	675813.VIB_000026	1.85e-135	389.0	COG0742@1|root,COG0742@2|Bacteria,1MX8Z@1224|Proteobacteria,1RMIB@1236|Gammaproteobacteria,1XTAA@135623|Vibrionales	135623|Vibrionales	J	Specifically methylates the guanosine in position 1516 of 16S rRNA	rsmJ	-	2.1.1.242	ko:K15984	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SAM_MT
k141_4357_4	1205908.AKXW01000023_gene820	6.96e-06	50.1	2ES0Z@1|root,33JK1@2|Bacteria,1NHKR@1224|Proteobacteria,1SI94@1236|Gammaproteobacteria,1XY8R@135623|Vibrionales	135623|Vibrionales	-	-	VC0074	-	-	-	-	-	-	-	-	-	-	-	-
k141_4357_5	1348635.BBJY01000028_gene2074	1.28e-160	455.0	COG0697@1|root,COG0697@2|Bacteria,1MWMC@1224|Proteobacteria,1RQST@1236|Gammaproteobacteria,1XTFF@135623|Vibrionales	135623|Vibrionales	EG	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily	yigM	-	-	-	-	-	-	-	-	-	-	-	EamA
k141_4357_6	1051646.VITU9109_19682	2.53e-71	217.0	COG0589@1|root,COG0589@2|Bacteria,1MV6Y@1224|Proteobacteria,1RQQ7@1236|Gammaproteobacteria,1XWVC@135623|Vibrionales	135623|Vibrionales	T	COG0589 Universal stress protein UspA and related nucleotide-binding proteins	uspA	-	-	ko:K06149	-	-	-	-	ko00000	-	-	-	Usp
k141_4357_8	1348635.BBJY01000028_gene2071	6.29e-44	145.0	291H9@1|root,2ZP3V@2|Bacteria,1RDHD@1224|Proteobacteria,1S3P8@1236|Gammaproteobacteria,1XXMB@135623|Vibrionales	135623|Vibrionales	S	Universal stress protein B homolog	uspB	-	-	ko:K06144	-	-	-	-	ko00000,ko02000	9.B.4.1.1	-	-	UspB
k141_4357_9	223926.28805061	3.81e-235	652.0	COG2081@1|root,COG2081@2|Bacteria,1MUGC@1224|Proteobacteria,1RNCW@1236|Gammaproteobacteria,1XSRR@135623|Vibrionales	135623|Vibrionales	S	HI0933-like protein	yhiN	-	-	ko:K07007	-	-	-	-	ko00000	-	-	-	HI0933_like
k141_4357_10	55601.VANGNB10_cI2668	5.29e-190	533.0	COG1172@1|root,COG1172@2|Bacteria,1MVN9@1224|Proteobacteria,1RPYE@1236|Gammaproteobacteria,1XWC5@135623|Vibrionales	135623|Vibrionales	U	Branched-chain amino acid transport system / permease component	-	-	-	ko:K10440,ko:K10538	ko02010,map02010	M00212,M00213	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19,3.A.1.2.2	-	-	BPD_transp_2
k141_4357_12	55601.VANGNB10_cI2666	1.75e-211	587.0	COG1879@1|root,COG1879@2|Bacteria,1MVDG@1224|Proteobacteria,1RMBR@1236|Gammaproteobacteria,1XTNH@135623|Vibrionales	135623|Vibrionales	G	Periplasmic binding protein domain	-	-	-	ko:K10537	ko02010,map02010	M00213	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.2	-	-	Peripla_BP_1
k141_4357_13	1348635.BBJY01000016_gene3971	2.07e-128	370.0	COG0235@1|root,COG0235@2|Bacteria,1MU54@1224|Proteobacteria,1RMIP@1236|Gammaproteobacteria,1XUM8@135623|Vibrionales	135623|Vibrionales	G	COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases	-	-	5.1.3.4	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	M00550	R05850	RC01479	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldolase_II
k141_4357_14	223926.28810078	3.71e-275	760.0	COG2160@1|root,COG2160@2|Bacteria,1MW0J@1224|Proteobacteria,1RQEF@1236|Gammaproteobacteria,1XSFJ@135623|Vibrionales	135623|Vibrionales	G	Catalyzes the conversion of L-arabinose to L-ribulose	araA	-	5.3.1.4	ko:K01804	ko00040,ko01100,map00040,map01100	-	R01761	RC00516	ko00000,ko00001,ko01000	-	-	-	Arabinose_Iso_C,Arabinose_Isome
k141_2962_1	1125863.JAFN01000001_gene3105	6.77e-05	47.4	COG1638@1|root,COG1638@2|Bacteria,1MVHC@1224|Proteobacteria,42N80@68525|delta/epsilon subdivisions,2WKQ7@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	Bacterial extracellular solute-binding protein, family 7	-	-	-	-	-	-	-	-	-	-	-	-	DctP
k141_2962_2	1265505.ATUG01000001_gene3315	1.14e-28	108.0	COG3090@1|root,COG3090@2|Bacteria,1RBHY@1224|Proteobacteria,42SS0@68525|delta/epsilon subdivisions,2WN7I@28221|Deltaproteobacteria,2MJNE@213118|Desulfobacterales	28221|Deltaproteobacteria	G	Tripartite ATP-independent periplasmic transporters, DctQ component	-	-	-	-	-	-	-	-	-	-	-	-	DctQ
k141_1353_1	55601.VANGNB10_cI1374c	8.68e-280	772.0	COG2723@1|root,COG2723@2|Bacteria,1MWG6@1224|Proteobacteria,1RMM2@1236|Gammaproteobacteria,1XSV6@135623|Vibrionales	135623|Vibrionales	G	Belongs to the glycosyl hydrolase 1 family	bglA	-	3.2.1.86	ko:K01223	ko00010,ko00500,map00010,map00500	-	R00839,R05133,R05134	RC00049,RC00171,RC00714	ko00000,ko00001,ko01000	-	GT1	-	Glyco_hydro_1
k141_1353_2	55601.VANGNB10_cI1373c	7.96e-126	370.0	COG1609@1|root,COG1609@2|Bacteria,1N4ND@1224|Proteobacteria,1RNR5@1236|Gammaproteobacteria,1XVKJ@135623|Vibrionales	135623|Vibrionales	K	Transcriptional regulator, LacI family	-	-	-	ko:K02529,ko:K03487	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
k141_1353_3	82995.CR62_08920	3.17e-37	128.0	COG1440@1|root,COG1440@2|Bacteria,1MZHX@1224|Proteobacteria,1S94Q@1236|Gammaproteobacteria,403QM@613|Serratia	1236|Gammaproteobacteria	G	Cytochrome C biogenesis protein CcmE	Z012_08190	-	2.7.1.196,2.7.1.205	ko:K02760	ko00500,ko02060,map00500,map02060	M00275	R11170,R11172	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.3.2	-	-	PTS_IIB
k141_1353_4	595494.Tola_2982	2.31e-233	651.0	COG1455@1|root,COG1455@2|Bacteria,1MXAG@1224|Proteobacteria,1RQGX@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane	-	-	-	ko:K02761	ko00500,ko02060,map00500,map02060	M00275	R11170,R11172	RC00017,RC03206	ko00000,ko00001,ko00002,ko02000	4.A.3.2	-	-	PTS_EIIC
k141_1353_5	316275.VSAL_I0707	3.39e-51	163.0	COG1447@1|root,COG1447@2|Bacteria,1N0T8@1224|Proteobacteria,1S9TV@1236|Gammaproteobacteria,1Y2MN@135623|Vibrionales	135623|Vibrionales	H	PTS system, Lactose/Cellobiose specific IIA subunit	-	-	2.7.1.196,2.7.1.205	ko:K02759	ko00500,ko02060,map00500,map02060	M00275	R11170,R11172	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.3.2	-	-	PTS_IIA
k141_1353_6	1123228.AUIH01000018_gene3533	2.46e-60	203.0	COG1609@1|root,COG1609@2|Bacteria,1MU1G@1224|Proteobacteria,1RMSP@1236|Gammaproteobacteria,1XMXW@135619|Oceanospirillales	135619|Oceanospirillales	K	helix_turn _helix lactose operon repressor	-	-	-	-	-	-	-	-	-	-	-	-	LacI,Peripla_BP_3
k141_1353_9	675816.VIA_001677	1.38e-218	617.0	COG1055@1|root,COG1055@2|Bacteria,1MUH8@1224|Proteobacteria,1RPSM@1236|Gammaproteobacteria,1XTNI@135623|Vibrionales	135623|Vibrionales	P	COG1055 Na H antiporter NhaD and related arsenite permeases	nhaD	-	-	-	-	-	-	-	-	-	-	-	CitMHS
k141_1353_10	675813.VIB_002505	7.76e-29	108.0	2AWJ9@1|root,31NFW@2|Bacteria,1QK6V@1224|Proteobacteria,1TIA2@1236|Gammaproteobacteria,1XYQN@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_1353_11	1136163.M565_ctg5P1475	5.31e-165	467.0	COG0583@1|root,COG0583@2|Bacteria,1MXXA@1224|Proteobacteria,1RREE@1236|Gammaproteobacteria,1XUTM@135623|Vibrionales	135623|Vibrionales	K	Transcriptional regulator	hdfR	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
k141_1353_12	345073.VC395_A1045	5.96e-56	176.0	COG3085@1|root,COG3085@2|Bacteria,1N4FH@1224|Proteobacteria,1SC65@1236|Gammaproteobacteria,1XXA3@135623|Vibrionales	135623|Vibrionales	S	protein conserved in bacteria	-	-	-	ko:K09897	-	-	-	-	ko00000	-	-	-	DUF413
k141_1353_14	345073.VC395_A1068	1.12e-313	872.0	COG2213@1|root,COG4668@1|root,COG2213@2|Bacteria,COG4668@2|Bacteria,1MUPU@1224|Proteobacteria,1RNAG@1236|Gammaproteobacteria,1XSK5@135623|Vibrionales	135623|Vibrionales	G	PTS system mannitol-specific transporter subunit IICBA	mtlA	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0008643,GO:0009401,GO:0015144,GO:0015166,GO:0015318,GO:0015575,GO:0015791,GO:0015797,GO:0015850,GO:0016020,GO:0016740,GO:0016772,GO:0016773,GO:0022804,GO:0022857,GO:0034219,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0090563,GO:1901618	2.7.1.197	ko:K02798,ko:K02799,ko:K02800	ko00051,ko02060,map00051,map02060	M00274	R02704	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.2.1.12,4.A.2.1.2,4.A.2.1.24,4.A.2.1.5	-	-	PTS_EIIA_2,PTS_EIIC,PTS_IIB
k141_1353_15	1517681.HW45_13985	5.58e-172	491.0	COG0246@1|root,COG0246@2|Bacteria,1MXV8@1224|Proteobacteria,1RPCP@1236|Gammaproteobacteria,1XTTE@135623|Vibrionales	135623|Vibrionales	C	hexitol metabolic process	mtlD	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006059,GO:0006066,GO:0008150,GO:0008152,GO:0008926,GO:0009056,GO:0009987,GO:0016052,GO:0016491,GO:0016614,GO:0016616,GO:0019400,GO:0019405,GO:0019407,GO:0019592,GO:0019594,GO:0019751,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044275,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046164,GO:0046174,GO:0055114,GO:0071704,GO:1901575,GO:1901615,GO:1901616	1.1.1.17	ko:K00009	ko00051,map00051	-	R02703	RC00085	ko00000,ko00001,ko01000	-	-	-	Mannitol_dh,Mannitol_dh_C
k141_1353_16	223926.28805351	7.69e-65	204.0	COG3722@1|root,COG3722@2|Bacteria,1NEDY@1224|Proteobacteria,1RPCM@1236|Gammaproteobacteria,1XVK5@135623|Vibrionales	135623|Vibrionales	K	Mannitol operon repressor	mtlR	-	-	ko:K02562	-	-	-	-	ko00000,ko03000	-	-	-	MtlR
k141_1353_17	1219065.VPR01S_19_00910	1.04e-111	325.0	COG0108@1|root,COG0108@2|Bacteria,1MU8P@1224|Proteobacteria,1RQ49@1236|Gammaproteobacteria,1XT0Y@135623|Vibrionales	135623|Vibrionales	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	ribB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0008686,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016829,GO:0016830,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.99.12	ko:K02858	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R07281	RC01792,RC01815	ko00000,ko00001,ko00002,ko01000	-	-	-	DHBP_synthase
k141_1353_19	1219065.VPR01S_12_01200	3.05e-123	359.0	COG2207@1|root,COG2207@2|Bacteria,1REAN@1224|Proteobacteria,1S3P2@1236|Gammaproteobacteria,1XTWJ@135623|Vibrionales	135623|Vibrionales	K	COG2207 AraC-type DNA-binding domain-containing proteins	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18,HTH_AraC
k141_1353_20	55601.VANGNB10_cII0994	1.11e-173	494.0	COG1196@1|root,COG1196@2|Bacteria,1QUH3@1224|Proteobacteria,1T1YQ@1236|Gammaproteobacteria,1Y330@135623|Vibrionales	135623|Vibrionales	D	PEGA domain	-	-	-	-	-	-	-	-	-	-	-	-	PEGA
k141_1353_21	1187848.AJYQ01000074_gene2124	2.67e-201	585.0	COG1262@1|root,COG1262@2|Bacteria,1NQ5K@1224|Proteobacteria,1RQVK@1236|Gammaproteobacteria,1XU7A@135623|Vibrionales	135623|Vibrionales	S	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,PEGA
k141_1353_22	243277.VC_A1079	1.26e-127	365.0	COG0259@1|root,COG0259@2|Bacteria,1NZUU@1224|Proteobacteria,1RMQ2@1236|Gammaproteobacteria,1XUNP@135623|Vibrionales	135623|Vibrionales	H	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP)	pdxH	GO:0003674,GO:0003824,GO:0004733,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016491,GO:0016638,GO:0016641,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046184,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	1.4.3.5	ko:K00275	ko00750,ko01100,ko01120,map00750,map01100,map01120	M00124	R00277,R00278,R01710,R01711	RC00048,RC00116	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_phzG_C,Putative_PNPOx
k141_1353_23	672.VV93_v1c45160	5.23e-96	286.0	COG3672@1|root,COG3672@2|Bacteria,1RDQS@1224|Proteobacteria,1S3Y1@1236|Gammaproteobacteria,1XST8@135623|Vibrionales	135623|Vibrionales	S	Periplasmic Protein	lapF	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C93
k141_1353_24	1219065.VPR01S_12_01270	2.36e-270	761.0	COG2199@1|root,COG2200@1|root,COG2199@2|Bacteria,COG2200@2|Bacteria,1MUQV@1224|Proteobacteria,1RN0Q@1236|Gammaproteobacteria,1XU7X@135623|Vibrionales	135623|Vibrionales	T	COG2199 FOG GGDEF domain	VVA1653	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,HAMP,LapD_MoxY_N
k141_1353_25	243277.VC_1077	9.24e-60	189.0	2AW20@1|root,31MWP@2|Bacteria,1QJNN@1224|Proteobacteria,1THPJ@1236|Gammaproteobacteria,1XX23@135623|Vibrionales	135623|Vibrionales	-	-	VC1077	-	-	-	-	-	-	-	-	-	-	-	-
k141_1353_26	55601.VANGNB10_cII1002c	5.89e-231	655.0	COG1315@1|root,COG1315@2|Bacteria,1R40D@1224|Proteobacteria,1RZ2U@1236|Gammaproteobacteria,1XT9Y@135623|Vibrionales	135623|Vibrionales	L	polymerase, most proteins contain PALM domain, HD hydrolase domain and Zn-ribbon domain	-	-	-	ko:K09749	-	-	-	-	ko00000	-	-	-	FapA
k141_1353_28	345073.VC395_A1132	1.58e-191	565.0	COG1444@1|root,COG1444@2|Bacteria,1NBA4@1224|Proteobacteria,1RPAM@1236|Gammaproteobacteria,1XT9I@135623|Vibrionales	135623|Vibrionales	J	Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP)	tmcA	GO:0000049,GO:0000154,GO:0002097,GO:0002101,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008080,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0022613,GO:0030490,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042274,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0051391,GO:0051392,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1904812,GO:1990882,GO:1990883,GO:1990884	2.3.1.193	ko:K06957	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF1726,GNAT_acetyltr_2,Helicase_RecD
k141_1353_29	672.VV93_v1c32680	2.25e-170	485.0	COG0687@1|root,COG0687@2|Bacteria,1MUYW@1224|Proteobacteria,1RM7W@1236|Gammaproteobacteria,1XUI9@135623|Vibrionales	135623|Vibrionales	P	Required for the activity of the bacterial periplasmic transport system of putrescine	-	-	-	ko:K11069	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	SBP_bac_8
k141_1353_30	675806.VII_000307	5.65e-161	459.0	COG1475@1|root,COG1475@2|Bacteria,1NGXR@1224|Proteobacteria,1RNZ3@1236|Gammaproteobacteria,1XSQH@135623|Vibrionales	135623|Vibrionales	K	Belongs to the ParB family	VVA1695	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
k141_1353_32	55601.VANGNB10_cII0001	0.0	1125.0	COG1284@1|root,COG1284@2|Bacteria,1RDIV@1224|Proteobacteria,1S7JN@1236|Gammaproteobacteria,1XSIE@135623|Vibrionales	135623|Vibrionales	S	Protein of unknown function (DUF3346)	rctB	-	-	-	-	-	-	-	-	-	-	-	DUF3346
k141_1353_34	55601.VANGNB10_cII0003	6.45e-27	99.4	2AWN9@1|root,31NJ0@2|Bacteria,1QK9N@1224|Proteobacteria,1TID5@1236|Gammaproteobacteria,1XYWS@135623|Vibrionales	135623|Vibrionales	-	-	VVA0005	-	-	-	-	-	-	-	-	-	-	-	-
k141_1353_35	675813.VIB_002551	2.33e-24	93.2	2C4PK@1|root,3333R@2|Bacteria,1N7VC@1224|Proteobacteria,1SCZA@1236|Gammaproteobacteria,1XYWF@135623|Vibrionales	135623|Vibrionales	S	Protein of unknown function (DUF3283)	VVA0009	-	-	-	-	-	-	-	-	-	-	-	DUF3283
k141_1353_37	316275.VSAL_II0163	1.96e-119	352.0	COG1622@1|root,COG1622@2|Bacteria,1MWHZ@1224|Proteobacteria,1RP4H@1236|Gammaproteobacteria,1XUJG@135623|Vibrionales	135623|Vibrionales	C	subunit 2	cyoA	-	1.10.3.10	ko:K02297	ko00190,ko01100,map00190,map01100	M00417	R11335	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.5	-	-	COX2,COX_ARM
k141_1353_38	1219065.VPR01S_13_01280	0.0	1150.0	COG0843@1|root,COG0843@2|Bacteria,1MU7S@1224|Proteobacteria,1RPC3@1236|Gammaproteobacteria,1XU9F@135623|Vibrionales	135623|Vibrionales	C	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B	cyoB	-	1.10.3.10	ko:K02298	ko00190,ko01100,map00190,map01100	M00417	R11335	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.5	-	-	COX1
k141_1353_39	316275.VSAL_II0161	5.55e-97	287.0	COG1845@1|root,COG1845@2|Bacteria,1MUCK@1224|Proteobacteria,1RN9D@1236|Gammaproteobacteria,1XVK1@135623|Vibrionales	135623|Vibrionales	C	oxidase, subunit	cyoC	-	-	ko:K02299	ko00190,ko01100,map00190,map01100	M00417	-	-	ko00000,ko00001,ko00002	3.D.4.5	-	-	COX3
k141_1353_40	82996.sch_05225	7.44e-24	94.7	COG3125@1|root,COG3125@2|Bacteria,1RHE5@1224|Proteobacteria,1S6KQ@1236|Gammaproteobacteria,403GF@613|Serratia	1236|Gammaproteobacteria	C	cytochrome C oxidase	cyoD	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009055,GO:0009060,GO:0009319,GO:0009486,GO:0009987,GO:0015002,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015453,GO:0015672,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0016021,GO:0016491,GO:0019646,GO:0022804,GO:0022857,GO:0022890,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0034220,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0051179,GO:0051234,GO:0055085,GO:0055114,GO:0070069,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1902494,GO:1902600	-	ko:K02300	ko00190,ko01100,map00190,map01100	M00417	-	-	ko00000,ko00001,ko00002	3.D.4.5	-	iAF1260.b0429,iB21_1397.B21_00384,iBWG_1329.BWG_0311,iE2348C_1286.E2348C_0364,iEC042_1314.EC042_0467,iEC55989_1330.EC55989_0443,iECBD_1354.ECBD_3229,iECB_1328.ECB_00380,iECDH10B_1368.ECDH10B_0385,iECDH1ME8569_1439.ECDH1ME8569_0414,iECD_1391.ECD_00380,iECED1_1282.ECED1_0452,iECH74115_1262.ECH74115_0513,iECIAI1_1343.ECIAI1_0432,iECIAI39_1322.ECIAI39_0244,iECO103_1326.ECO103_0406,iECO111_1330.ECO111_0462,iECO26_1355.ECO26_0464,iECOK1_1307.ECOK1_0409,iECP_1309.ECP_0489,iECS88_1305.ECS88_0425,iECSE_1348.ECSE_0454,iECSF_1327.ECSF_0389,iECSP_1301.ECSP_0497,iECUMN_1333.ECUMN_0468,iECW_1372.ECW_m0501,iECs_1301.ECs0483,iEKO11_1354.EKO11_3417,iEcDH1_1363.EcDH1_3180,iEcE24377_1341.EcE24377A_0464,iEcHS_1320.EcHS_A0504,iEcSMS35_1347.EcSMS35_0469,iEcolC_1368.EcolC_3204,iG2583_1286.G2583_0541,iJO1366.b0429,iJR904.b0429,iLF82_1304.LF82_0407,iNRG857_1313.NRG857_02020,iSBO_1134.SBO_0323,iSSON_1240.SSON_0412,iUMN146_1321.UM146_15215,iUMNK88_1353.UMNK88_479,iUTI89_1310.UTI89_C0452,iWFL_1372.ECW_m0501,iY75_1357.Y75_RS02215,iYL1228.KPN_00391,iZ_1308.Z0532	COX4_pro
k141_1353_41	1219065.VPR01S_13_01310	1.12e-122	359.0	COG0109@1|root,COG0109@2|Bacteria,1MW3S@1224|Proteobacteria,1RNHC@1236|Gammaproteobacteria,1XUYC@135623|Vibrionales	135623|Vibrionales	O	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group	cyoE	-	2.5.1.141	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	M00154	R07411	RC01786	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	-	-	-	UbiA
k141_1353_42	243277.VC_A0011	8.3e-78	271.0	COG2909@1|root,COG2909@2|Bacteria,1MVZZ@1224|Proteobacteria,1RN29@1236|Gammaproteobacteria,1XUE3@135623|Vibrionales	135623|Vibrionales	K	Positively regulates the transcription of the maltose regulon whose gene products are responsible for uptake and catabolism of malto-oligosaccharides. Binds and recognizes a DNA motif (called the malT box) 5'-GGA TG GA-3'	malT	GO:0003674,GO:0003700,GO:0005975,GO:0006355,GO:0008150,GO:0008152,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044238,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2001141	-	ko:K03556	-	-	-	-	ko00000,ko03000	-	-	-	GerE
k141_1353_43	345073.VC395_A0011	0.0	1380.0	COG0058@1|root,COG0058@2|Bacteria,1MW4J@1224|Proteobacteria,1RN8P@1236|Gammaproteobacteria,1XSRI@135623|Vibrionales	135623|Vibrionales	G	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties	malP	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	Phosphorylase
k141_1353_44	243277.VC_A0014	0.0	1046.0	COG1640@1|root,COG1640@2|Bacteria,1QTVJ@1224|Proteobacteria,1RMJW@1236|Gammaproteobacteria,1XTQ7@135623|Vibrionales	135623|Vibrionales	G	4-alpha-glucanotransferase	malQ	-	2.4.1.25	ko:K00705	ko00500,ko01100,map00500,map01100	-	R05196	RC00049	ko00000,ko00001,ko01000	-	GH77	-	Glyco_hydro_77
k141_1353_45	1517681.HW45_14480	0.0	1184.0	COG0296@1|root,COG0296@2|Bacteria,1QTVN@1224|Proteobacteria,1RQSK@1236|Gammaproteobacteria,1XU7M@135623|Vibrionales	135623|Vibrionales	G	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position	glgB	GO:0000271,GO:0003674,GO:0003824,GO:0003844,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0055114,GO:0071704,GO:1901576	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_48
k141_1353_47	55601.VANGNB10_cII0974c	2.62e-276	793.0	COG3409@1|root,COG3501@1|root,COG3409@2|Bacteria,COG3501@2|Bacteria,1MU7Q@1224|Proteobacteria,1RMZS@1236|Gammaproteobacteria,1XUHW@135623|Vibrionales	135623|Vibrionales	M	protein conserved in bacteria	vgrG1	GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0006464,GO:0006807,GO:0006996,GO:0007010,GO:0007015,GO:0008144,GO:0008150,GO:0008152,GO:0008154,GO:0009405,GO:0009987,GO:0016043,GO:0016874,GO:0016879,GO:0016881,GO:0017076,GO:0018149,GO:0018153,GO:0018193,GO:0018199,GO:0018205,GO:0018262,GO:0018995,GO:0019538,GO:0022411,GO:0030029,GO:0030036,GO:0030042,GO:0030430,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032984,GO:0033643,GO:0033646,GO:0035639,GO:0036094,GO:0036211,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0043624,GO:0043656,GO:0043657,GO:0043933,GO:0044215,GO:0044216,GO:0044217,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044419,GO:0046872,GO:0051261,GO:0051704,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:0097435,GO:1901265,GO:1901363,GO:1901564	-	ko:K11904	ko03070,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	PG_binding_1,Phage_GPD
k141_1353_48	675815.VOA_001153	2.85e-84	261.0	COG4104@1|root,COG4104@2|Bacteria,1RFZM@1224|Proteobacteria,1S4IZ@1236|Gammaproteobacteria,1XWB1@135623|Vibrionales	135623|Vibrionales	S	Domain of unknown function (DUF4123)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4123
k141_1353_49	1232683.ADIMK_1108	1.21e-287	838.0	COG1388@1|root,COG1388@2|Bacteria,1NDDK@1224|Proteobacteria,1S1MQ@1236|Gammaproteobacteria,469EJ@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_1353_50	675815.VOA_001155	8.57e-101	309.0	2BVAJ@1|root,32QQD@2|Bacteria,1RJBU@1224|Proteobacteria,1S8H8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_1669_1	1291050.JAGE01000001_gene657	1.44e-32	121.0	COG0703@1|root,COG0703@2|Bacteria	2|Bacteria	F	shikimate kinase activity	aroK	GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615	2.7.1.71,4.2.3.4	ko:K00891,ko:K13829	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412,R03083	RC00002,RC00078,RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	SKI
k141_1669_3	1121374.KB891575_gene1168	1.61e-50	168.0	2DC7E@1|root,2ZD5M@2|Bacteria,1RC9H@1224|Proteobacteria,1S3D4@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	LPP20
k141_988_1	1265505.ATUG01000002_gene2653	3.29e-158	461.0	COG2271@1|root,COG2271@2|Bacteria,1QUF4@1224|Proteobacteria,43BV2@68525|delta/epsilon subdivisions,2X761@28221|Deltaproteobacteria,2MPKS@213118|Desulfobacterales	28221|Deltaproteobacteria	G	Acetyl-coenzyme A transporter 1	-	-	-	ko:K08218	ko01501,map01501	M00628	-	-	ko00000,ko00001,ko00002,ko02000	2.A.1.25	-	-	MFS_1
k141_988_2	177437.HRM2_37490	1.5e-98	292.0	COG0127@1|root,COG0127@2|Bacteria,1MUK5@1224|Proteobacteria,42NGT@68525|delta/epsilon subdivisions,2WK3E@28221|Deltaproteobacteria,2MI23@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions	rdgB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	iAF987.Gmet_1875	Ham1p_like
k141_988_3	641107.CDLVIII_1888	1.75e-57	186.0	COG0778@1|root,COG0778@2|Bacteria,1V4ZI@1239|Firmicutes,24BD0@186801|Clostridia,36H2X@31979|Clostridiaceae	186801|Clostridia	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
k141_990_1	1121439.dsat_0389	1.87e-13	74.7	COG0840@1|root,COG0840@2|Bacteria,1RE5G@1224|Proteobacteria,42SBI@68525|delta/epsilon subdivisions,2WPRK@28221|Deltaproteobacteria,2M8I1@213115|Desulfovibrionales	28221|Deltaproteobacteria	NT	PFAM chemotaxis sensory transducer	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal,dCache_1
k141_1670_1	316067.Geob_1577	3.36e-135	414.0	COG0751@1|root,COG0751@2|Bacteria,1MV2F@1224|Proteobacteria,42M6A@68525|delta/epsilon subdivisions,2WJIT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Glycyl-tRNA synthetase beta subunit	glyS	-	6.1.1.14	ko:K01879	ko00970,map00970	M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_1,tRNA_synt_2f
k141_991_1	316275.VSAL_II1026	2.02e-48	163.0	COG0180@1|root,COG0180@2|Bacteria,1MV4T@1224|Proteobacteria,1RNDC@1236|Gammaproteobacteria,1XSTM@135623|Vibrionales	135623|Vibrionales	J	Belongs to the class-I aminoacyl-tRNA synthetase family	-	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
k141_2670_1	1219065.VPR01S_07_01600	9.04e-22	92.8	2AXJM@1|root,31PJR@2|Bacteria,1QJUS@1224|Proteobacteria,1THW8@1236|Gammaproteobacteria,1XXQC@135623|Vibrionales	135623|Vibrionales	-	-	VV20220	-	-	-	-	-	-	-	-	-	-	-	-
k141_2670_2	243277.VC_A0227	4.77e-62	202.0	COG4607@1|root,COG4607@2|Bacteria,1R54Y@1224|Proteobacteria,1RZ1I@1236|Gammaproteobacteria,1XURC@135623|Vibrionales	135623|Vibrionales	P	Periplasmic binding protein	vctP	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
k141_2985_2	945543.VIBR0546_12262	4.53e-122	370.0	COG1388@1|root,COG1388@2|Bacteria,1RC2P@1224|Proteobacteria,1T2A3@1236|Gammaproteobacteria,1XSVD@135623|Vibrionales	135623|Vibrionales	M	LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_2985_3	945543.VIBR0546_12267	1.56e-31	114.0	2AW90@1|root,31N4B@2|Bacteria,1QJVS@1224|Proteobacteria,1THXD@1236|Gammaproteobacteria,1XXT9@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_1672_1	1348635.BBJY01000005_gene3259	2.77e-140	409.0	2CG2X@1|root,2Z7NT@2|Bacteria,1MW33@1224|Proteobacteria,1RQZI@1236|Gammaproteobacteria,1XSII@135623|Vibrionales	135623|Vibrionales	-	-	VP1614	-	-	-	-	-	-	-	-	-	-	-	-
k141_1672_2	243277.VC_1503	9.78e-96	286.0	COG2996@1|root,COG2996@2|Bacteria,1MXC3@1224|Proteobacteria,1RS4D@1236|Gammaproteobacteria,1XTG1@135623|Vibrionales	135623|Vibrionales	S	protein conserved in bacteria	-	-	-	ko:K00243	-	-	-	-	ko00000	-	-	-	S1_2
k141_2986_1	1304885.AUEY01000037_gene2183	7.38e-99	300.0	COG0452@1|root,COG0452@2|Bacteria,1MVQP@1224|Proteobacteria,42NIG@68525|delta/epsilon subdivisions,2WIR1@28221|Deltaproteobacteria,2MHMV@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	coaBC	-	4.1.1.36,6.3.2.5	ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
k141_1449_2	672.VV93_v1c06220	1.3e-155	443.0	COG0583@1|root,COG0583@2|Bacteria,1MVHT@1224|Proteobacteria,1RN7G@1236|Gammaproteobacteria,1XT8V@135623|Vibrionales	135623|Vibrionales	K	Transcriptional activator	nhaR	GO:0003674,GO:0003700,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2001141	-	ko:K03717	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,LysR_substrate
k141_1449_3	1348635.BBJY01000001_gene2443	1.41e-53	172.0	COG0071@1|root,COG0071@2|Bacteria,1N7C7@1224|Proteobacteria,1S607@1236|Gammaproteobacteria,1XYRW@135623|Vibrionales	135623|Vibrionales	O	Hsp20/alpha crystallin family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
k141_1449_4	351746.Pput_5043	1.2e-143	411.0	COG0207@1|root,COG0207@2|Bacteria,1MUBD@1224|Proteobacteria,1RPYV@1236|Gammaproteobacteria,1YY8H@136845|Pseudomonas putida group	1236|Gammaproteobacteria	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis	thyA	GO:0000287,GO:0003674,GO:0003824,GO:0004799,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006220,GO:0006221,GO:0006231,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009157,GO:0009162,GO:0009165,GO:0009176,GO:0009177,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009314,GO:0009394,GO:0009628,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019438,GO:0019637,GO:0019692,GO:0032259,GO:0034641,GO:0034654,GO:0042083,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046073,GO:0046385,GO:0046483,GO:0046872,GO:0050896,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.1.1.45	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	M00053	R02101	RC00219,RC00332	ko00000,ko00001,ko00002,ko01000	-	-	iAF1260.b2827,iAPECO1_1312.APECO1_3678,iBWG_1329.BWG_2562,iE2348C_1286.E2348C_3096,iEC042_1314.EC042_3024,iEC55989_1330.EC55989_3103,iECABU_c1320.ECABU_c31240,iECDH10B_1368.ECDH10B_2997,iECDH1ME8569_1439.ECDH1ME8569_2734,iECED1_1282.ECED1_3283,iECH74115_1262.ECH74115_4093,iECIAI1_1343.ECIAI1_2935,iECIAI39_1322.ECIAI39_3246,iECNA114_1301.ECNA114_2885,iECO103_1326.ECO103_3386,iECO111_1330.ECO111_3555,iECO26_1355.ECO26_3899,iECOK1_1307.ECOK1_3231,iECP_1309.ECP_2840,iECS88_1305.ECS88_3122,iECSE_1348.ECSE_3084,iECSF_1327.ECSF_2642,iECSP_1301.ECSP_3779,iECUMN_1333.ECUMN_3154,iECW_1372.ECW_m3069,iECs_1301.ECs3684,iEKO11_1354.EKO11_0914,iETEC_1333.ETEC_3014,iEcDH1_1363.EcDH1_0864,iEcE24377_1341.EcE24377A_3147,iEcSMS35_1347.EcSMS35_2974,iG2583_1286.G2583_3481,iJO1366.b2827,iJR904.b2827,iLF82_1304.LF82_2267,iNRG857_1313.NRG857_13965,iSSON_1240.SSON_2984,iUMN146_1321.UM146_02290,iUMNK88_1353.UMNK88_3511,iUTI89_1310.UTI89_C3229,iWFL_1372.ECW_m3069,iY75_1357.Y75_RS14705,iYL1228.KPN_03236,iZ_1308.Z4144,ic_1306.c3422	Thymidylat_synt
k141_1449_6	55601.VANGNB10_cI0571	6.64e-154	436.0	COG0682@1|root,COG0682@2|Bacteria,1MVE3@1224|Proteobacteria,1RMVK@1236|Gammaproteobacteria,1XSP4@135623|Vibrionales	135623|Vibrionales	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
k141_1449_7	1219077.VAZ01S_045_00220	8.69e-98	294.0	COG0730@1|root,COG0730@2|Bacteria,1R3V4@1224|Proteobacteria,1RVNC@1236|Gammaproteobacteria,1XUH0@135623|Vibrionales	135623|Vibrionales	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
k141_1449_8	55601.VANGNB10_cI0569	0.0	1110.0	COG3605@1|root,COG3605@2|Bacteria,1QTTV@1224|Proteobacteria,1T1H2@1236|Gammaproteobacteria,1XSXI@135623|Vibrionales	135623|Vibrionales	T	Belongs to the PEP-utilizing enzyme family	ptsP	-	2.7.3.9	ko:K08484	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	-	-	-	GAF,PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C
k141_1449_9	675815.VOA_003180	2.25e-116	333.0	COG0494@1|root,COG0494@2|Bacteria,1RDGJ@1224|Proteobacteria,1S3PQ@1236|Gammaproteobacteria,1XUD3@135623|Vibrionales	135623|Vibrionales	L	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage	nudH	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0019222,GO:0019439,GO:0033554,GO:0034353,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0050896,GO:0051716,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575	-	ko:K08311	ko03018,map03018	-	R10816	RC00002	ko00000,ko00001,ko01000,ko03019	-	-	-	NUDIX
k141_1449_10	945550.VISI1226_17941	2.39e-130	373.0	COG3066@1|root,COG3066@2|Bacteria,1MVYX@1224|Proteobacteria,1RQVV@1236|Gammaproteobacteria,1XV3G@135623|Vibrionales	135623|Vibrionales	L	Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair	mutH	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360	-	ko:K03573	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutH
k141_1449_11	675806.VII_003082	6.32e-194	544.0	COG0667@1|root,COG0667@2|Bacteria,1MV2Y@1224|Proteobacteria,1RNXH@1236|Gammaproteobacteria,1XTZ8@135623|Vibrionales	135623|Vibrionales	C	oxidoreductases (related to aryl-alcohol dehydrogenases)	tas	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
k141_1449_12	595494.Tola_2985	4.22e-23	91.7	COG4095@1|root,COG4095@2|Bacteria,1N759@1224|Proteobacteria,1SD0E@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	MtN3 and saliva related transmembrane protein	-	-	-	ko:K15383	-	-	-	-	ko00000,ko02000	9.A.58.2	-	-	PQ-loop
k141_1449_14	1348635.BBJY01000002_gene3516	0.0	896.0	COG1190@1|root,COG1190@2|Bacteria,1MX1V@1224|Proteobacteria,1RMJN@1236|Gammaproteobacteria,1XSNE@135623|Vibrionales	135623|Vibrionales	J	Belongs to the class-II aminoacyl-tRNA synthetase family	lysS	GO:0003674,GO:0003824,GO:0004812,GO:0004824,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006430,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
k141_1449_15	1248232.BANQ01000008_gene1915	1.73e-227	629.0	COG1186@1|root,COG1186@2|Bacteria,1MUAW@1224|Proteobacteria,1RP9Z@1236|Gammaproteobacteria,1XSN5@135623|Vibrionales	135623|Vibrionales	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	-	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
k141_1449_16	672.VV93_v1c06020	9.42e-203	575.0	COG1114@1|root,COG1114@2|Bacteria,1MVIF@1224|Proteobacteria,1RR3P@1236|Gammaproteobacteria,1XTP0@135623|Vibrionales	135623|Vibrionales	U	Component of the transport system for branched-chain amino acids	brnQ	-	-	ko:K03311	-	-	-	-	ko00000	2.A.26	-	-	Branch_AA_trans
k141_1449_17	1348635.BBJY01000002_gene3520	5.17e-74	232.0	COG4123@1|root,COG4123@2|Bacteria,1PC8R@1224|Proteobacteria,1RM8S@1236|Gammaproteobacteria,1XTHE@135623|Vibrionales	135623|Vibrionales	J	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)	yfiC	GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016426,GO:0016430,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.1.1.223	ko:K15460	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	MTS
k141_1449_18	1348635.BBJY01000002_gene3521	8.89e-241	668.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,1RMWA@1236|Gammaproteobacteria,1XSEA@135623|Vibrionales	135623|Vibrionales	F	DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit at low temperature. Exhibits RNA-stimulated ATP hydrolysis and RNA unwinding activity	srmB	-	3.6.4.13	ko:K05590	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	DEAD,Helicase_C
k141_1449_19	55601.VANGNB10_cI0558	0.0	959.0	COG4108@1|root,COG4108@2|Bacteria,1MU7X@1224|Proteobacteria,1RMFT@1236|Gammaproteobacteria,1XVAZ@135623|Vibrionales	135623|Vibrionales	J	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP	prfC	GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016150,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02837	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,RF3_C
k141_1449_21	1238450.VIBNISOn1_1830004	1.07e-209	602.0	COG4618@1|root,COG4618@2|Bacteria,1NTI5@1224|Proteobacteria,1T1HR@1236|Gammaproteobacteria,1XUAM@135623|Vibrionales	135623|Vibrionales	V	COG4618 ABC-type protease lipase transport system, ATPase and permease components	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
k141_1449_22	1238450.VIBNISOn1_1830005	7.15e-172	496.0	COG0845@1|root,COG0845@2|Bacteria,1MUI8@1224|Proteobacteria,1RNK4@1236|Gammaproteobacteria,1XVAQ@135623|Vibrionales	135623|Vibrionales	M	COG0845 Membrane-fusion protein	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD,HlyD_3
k141_1449_25	322710.Avin_29890	2.49e-23	96.3	COG0394@1|root,COG0394@2|Bacteria,1N0DZ@1224|Proteobacteria,1S92S@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Belongs to the low molecular weight phosphotyrosine protein phosphatase family	wzb	GO:0000271,GO:0003674,GO:0003824,GO:0004721,GO:0004725,GO:0005975,GO:0005976,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009242,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019538,GO:0033692,GO:0034637,GO:0034645,GO:0035335,GO:0036211,GO:0042578,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044267,GO:0046377,GO:0071704,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901576	3.1.3.48	ko:K01104,ko:K20945	ko05111,map05111	-	-	-	ko00000,ko00001,ko01000	-	-	-	LMWPc
k141_1449_26	983545.Glaag_3326	5.14e-154	476.0	COG2931@1|root,COG2931@2|Bacteria,1R4HP@1224|Proteobacteria,1RQ1Y@1236|Gammaproteobacteria,46607@72275|Alteromonadaceae	1236|Gammaproteobacteria	Q	Right handed beta helix region	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_4834_1	1408439.JHXW01000010_gene115	8.99e-49	160.0	COG1846@1|root,COG1846@2|Bacteria,37BAW@32066|Fusobacteria	32066|Fusobacteria	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR
k141_4834_2	1121324.CLIT_2c01540	2.53e-80	244.0	COG1878@1|root,COG1878@2|Bacteria,1V2DJ@1239|Firmicutes,24HUC@186801|Clostridia	186801|Clostridia	S	cyclase family	-	-	-	-	-	-	-	-	-	-	-	-	Cyclase
k141_4834_7	140626.JHWB01000022_gene2132	1.09e-48	170.0	COG2816@1|root,COG2816@2|Bacteria,1TRMF@1239|Firmicutes,24AXA@186801|Clostridia	186801|Clostridia	L	Psort location Cytoplasmic, score	nudC	-	3.6.1.22	ko:K03426	ko00760,ko01100,ko04146,map00760,map01100,map04146	-	R00103,R03004,R11104	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX,NUDIX-like,zf-NADH-PPase
k141_4834_8	1511.CLOST_1046	0.0	1108.0	COG1061@1|root,COG3886@1|root,COG1061@2|Bacteria,COG3886@2|Bacteria,1TQ62@1239|Firmicutes,249TK@186801|Clostridia,25SIU@186804|Peptostreptococcaceae	186801|Clostridia	KL	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF3427,Helicase_C,PLDc_2,ResIII
k141_1126_2	96561.Dole_0540	3.59e-68	214.0	COG0353@1|root,COG0353@2|Bacteria,1MV9Q@1224|Proteobacteria,42QZJ@68525|delta/epsilon subdivisions,2WNCH@28221|Deltaproteobacteria,2MIIY@213118|Desulfobacterales	28221|Deltaproteobacteria	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecR,Toprim_4
k141_1126_3	96561.Dole_0541	1.6e-45	149.0	COG0718@1|root,COG0718@2|Bacteria,1RGZD@1224|Proteobacteria,42TGQ@68525|delta/epsilon subdivisions,2WQ6R@28221|Deltaproteobacteria,2MK5K@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection	-	-	-	ko:K09747	-	-	-	-	ko00000	-	-	-	YbaB_DNA_bd
k141_1126_4	96561.Dole_0542	2.34e-118	369.0	COG2812@1|root,COG2812@2|Bacteria,1MVCK@1224|Proteobacteria,42M09@68525|delta/epsilon subdivisions,2WJ1G@28221|Deltaproteobacteria,2MHZQ@213118|Desulfobacterales	28221|Deltaproteobacteria	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
k141_1463_1	1201293.AKXQ01000044_gene1000	1.56e-129	383.0	COG3177@1|root,COG3177@2|Bacteria,1MXWY@1224|Proteobacteria,1RXR7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Fic/DOC family	-	-	-	-	-	-	-	-	-	-	-	-	Fic
k141_2117_1	1121396.KB893085_gene344	0.0	1196.0	COG1020@1|root,COG3321@1|root,COG1020@2|Bacteria,COG3321@2|Bacteria,1QK4F@1224|Proteobacteria,42Z5Y@68525|delta/epsilon subdivisions,2X8JI@28221|Deltaproteobacteria,2MMZD@213118|Desulfobacterales	28221|Deltaproteobacteria	Q	Condensation domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_1,Condensation,KAsynt_C_assoc,KR,Ketoacyl-synt_C,PP-binding,PS-DH,ketoacyl-synt
k141_4544_1	1122217.KB899573_gene2184	6.98e-20	89.4	COG1284@1|root,COG1284@2|Bacteria,1TR9J@1239|Firmicutes,4H92U@909932|Negativicutes	909932|Negativicutes	S	Psort location CytoplasmicMembrane, score 10.00	-	-	-	-	-	-	-	-	-	-	-	-	DUF2179,YitT_membrane
k141_4544_2	1121403.AUCV01000004_gene2010	5.79e-95	289.0	COG0320@1|root,COG0320@2|Bacteria,1MVRD@1224|Proteobacteria,42P2E@68525|delta/epsilon subdivisions,2WIJQ@28221|Deltaproteobacteria,2MIZC@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives	lipA	-	2.8.1.8	ko:K03644	ko00785,ko01100,map00785,map01100	-	R07767,R07768	RC01978	ko00000,ko00001,ko01000	-	-	-	LIAS_N,Radical_SAM
k141_4544_3	1121434.AULY01000007_gene1135	6.38e-35	130.0	COG0321@1|root,COG0321@2|Bacteria,1MU6A@1224|Proteobacteria,42RIC@68525|delta/epsilon subdivisions,2WNRX@28221|Deltaproteobacteria,2MA16@213115|Desulfovibrionales	28221|Deltaproteobacteria	H	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate	lipB	GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564	2.3.1.181	ko:K03801	ko00785,ko01100,map00785,map01100	-	R07766,R07769	RC00039,RC00992,RC02867	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB
k141_4544_4	706587.Desti_1464	4.17e-195	555.0	COG1003@1|root,COG1003@2|Bacteria,1MUDP@1224|Proteobacteria,42MR9@68525|delta/epsilon subdivisions,2WIP3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvP	-	1.4.4.2	ko:K00281,ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko00002,ko01000	-	-	-	Aminotran_5,GDC-P
k141_1804_1	671143.DAMO_2946	2.79e-28	116.0	COG0187@1|root,COG0187@2|Bacteria,2NNSN@2323|unclassified Bacteria	2|Bacteria	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003916,GO:0003918,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006265,GO:0006351,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009295,GO:0009330,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019438,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032774,GO:0032991,GO:0034335,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0042221,GO:0042493,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0097367,GO:0097659,GO:0140097,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
k141_3831_1	1123075.AUDP01000007_gene2736	1.02e-13	76.6	COG0642@1|root,COG0745@1|root,COG0784@1|root,COG0745@2|Bacteria,COG0784@2|Bacteria,COG2205@2|Bacteria,1TQMV@1239|Firmicutes,247SE@186801|Clostridia,3WGVD@541000|Ruminococcaceae	186801|Clostridia	T	Response regulator receiver domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,PAS_9,Response_reg
k141_3831_3	1265505.ATUG01000001_gene4428	5.8e-40	137.0	2CR0D@1|root,32SN5@2|Bacteria,1N181@1224|Proteobacteria,42U36@68525|delta/epsilon subdivisions,2WQW4@28221|Deltaproteobacteria,2MKEU@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_3831_4	1144305.PMI02_00759	7.22e-07	55.5	COG0657@1|root,COG0657@2|Bacteria,1NEXK@1224|Proteobacteria,2TUVX@28211|Alphaproteobacteria,2K6QB@204457|Sphingomonadales	204457|Sphingomonadales	I	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3
k141_1805_1	1242864.D187_009072	1.73e-19	94.7	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42KZR@68525|delta/epsilon subdivisions,2WJ2T@28221|Deltaproteobacteria,2YY14@29|Myxococcales	28221|Deltaproteobacteria	NT	Four helix bundle sensory module for signal transduction	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,CHASE3,HAMP,MCPsignal
k141_2118_2	1121448.DGI_3049	8.11e-14	75.5	2CA2P@1|root,32RQH@2|Bacteria,1RBUS@1224|Proteobacteria,42XSD@68525|delta/epsilon subdivisions,2WVM8@28221|Deltaproteobacteria,2MDPW@213115|Desulfovibrionales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_2118_3	765913.ThidrDRAFT_2582	6.32e-37	136.0	COG1131@1|root,COG1131@2|Bacteria,1R3XF@1224|Proteobacteria,1S1UI@1236|Gammaproteobacteria,1X0I2@135613|Chromatiales	135613|Chromatiales	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
k141_4872_1	1121405.dsmv_1573	3.33e-228	645.0	COG1236@1|root,COG1236@2|Bacteria,1MUDD@1224|Proteobacteria,42N91@68525|delta/epsilon subdivisions,2WIMM@28221|Deltaproteobacteria,2MIKE@213118|Desulfobacterales	28221|Deltaproteobacteria	J	RNA-metabolising metallo-beta-lactamase	-	-	-	ko:K07576	-	-	-	-	ko00000	-	-	-	Beta-Casp,Lactamase_B,Lactamase_B_6,RMMBL
k141_3833_2	313624.NSP_37990	2.05e-34	133.0	COG1216@1|root,COG1216@2|Bacteria,1G9WK@1117|Cyanobacteria	1117|Cyanobacteria	S	Glycosyl transferase family 2	-	-	-	ko:K13683	-	-	-	-	ko00000,ko01000,ko01003	-	GT2	-	Glycos_transf_2
k141_4873_1	675813.VIB_001625	2e-85	264.0	COG0510@1|root,COG0510@2|Bacteria,1MURU@1224|Proteobacteria,1RNUN@1236|Gammaproteobacteria,1XTBI@135623|Vibrionales	135623|Vibrionales	M	choline kinase involved in LPS biosynthesis	thiK	-	-	-	-	-	-	-	-	-	-	-	APH,Choline_kinase
k141_4153_1	204669.Acid345_3733	2.95e-48	174.0	COG2223@1|root,COG2223@2|Bacteria,3Y3PZ@57723|Acidobacteria,2JICB@204432|Acidobacteriia	204432|Acidobacteriia	P	Major Facilitator Superfamily	-	-	-	ko:K08177	-	-	-	-	ko00000,ko02000	2.A.1.11	-	-	MFS_1
k141_4153_2	207559.Dde_3641	9.2e-290	817.0	COG0659@1|root,COG0659@2|Bacteria,1MWDF@1224|Proteobacteria,43AD6@68525|delta/epsilon subdivisions,2WJCC@28221|Deltaproteobacteria,2M8PA@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	transporter antisigma-factor antagonist STAS	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
k141_2120_1	1187848.AJYQ01000005_gene359	4.74e-102	311.0	COG2067@1|root,COG2067@2|Bacteria,1NM5K@1224|Proteobacteria,1SKF5@1236|Gammaproteobacteria,1XSQN@135623|Vibrionales	135623|Vibrionales	I	long-chain fatty acid transport protein	fadL	-	-	ko:K06076	-	-	-	-	ko00000,ko02000	1.B.9	-	-	Toluene_X
k141_1127_1	1408428.JNJP01000004_gene2869	4.1e-44	151.0	COG3721@1|root,COG3721@2|Bacteria,1RJ4R@1224|Proteobacteria,42SH4@68525|delta/epsilon subdivisions,2WV8J@28221|Deltaproteobacteria,2MEY0@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	Haem utilisation ChuX/HutX	-	-	-	-	-	-	-	-	-	-	-	-	ChuX_HutX
k141_1127_2	563192.HMPREF0179_03214	3.24e-58	186.0	COG0716@1|root,COG0716@2|Bacteria,1RJCS@1224|Proteobacteria,42RVT@68525|delta/epsilon subdivisions,2WPKG@28221|Deltaproteobacteria,2MBTZ@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	Flavodoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	Flavodoxin_3
k141_1127_3	1408428.JNJP01000004_gene2863	8.06e-30	114.0	COG1321@1|root,COG1321@2|Bacteria,1RHIK@1224|Proteobacteria,42SAD@68525|delta/epsilon subdivisions,2WPIC@28221|Deltaproteobacteria,2MD9V@213115|Desulfovibrionales	28221|Deltaproteobacteria	K	Helix-turn-helix diphteria tox regulatory element	-	-	-	ko:K03709	-	-	-	-	ko00000,ko03000	-	-	-	Fe_dep_repr_C,Fe_dep_repress,FeoA
k141_1127_4	1121438.JNJA01000004_gene897	6.96e-173	509.0	COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,43C63@68525|delta/epsilon subdivisions,2WJ61@28221|Deltaproteobacteria,2M9DR@213115|Desulfovibrionales	28221|Deltaproteobacteria	V	ABC transporter, transmembrane	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
k141_2780_1	575788.VS_1118	6.13e-65	207.0	COG1729@1|root,COG1729@2|Bacteria,1MUSV@1224|Proteobacteria,1RQWA@1236|Gammaproteobacteria,1XSAP@135623|Vibrionales	135623|Vibrionales	D	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division	cpoB	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6,TPR_8,TolA_bind_tri
k141_2780_2	29495.EA26_06275	5.58e-215	598.0	COG0379@1|root,COG0379@2|Bacteria,1MWQU@1224|Proteobacteria,1RMFS@1236|Gammaproteobacteria,1XTIU@135623|Vibrionales	135623|Vibrionales	H	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate	nadA	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.5.1.72	ko:K03517	ko00760,ko01100,map00760,map01100	M00115	R04292	RC01119	ko00000,ko00001,ko00002,ko01000	-	-	-	NadA
k141_2780_3	1348635.BBJY01000013_gene966	2.92e-76	233.0	COG3318@1|root,COG3318@2|Bacteria,1N0JQ@1224|Proteobacteria,1SUIC@1236|Gammaproteobacteria,1XTR3@135623|Vibrionales	135623|Vibrionales	S	Belongs to the UPF0149 family	-	-	-	ko:K07039	-	-	-	-	ko00000	-	-	-	UPF0149
k141_2780_4	675814.VIC_004549	8.85e-264	755.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,1SKKJ@1236|Gammaproteobacteria,1XT1G@135623|Vibrionales	135623|Vibrionales	T	COG0642 Signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,Response_reg,dCache_1
k141_2780_5	945550.VISI1226_13386	5.48e-38	131.0	2940Y@1|root,2ZRFS@2|Bacteria,1RF8A@1224|Proteobacteria,1RZCB@1236|Gammaproteobacteria,1XX6B@135623|Vibrionales	135623|Vibrionales	U	L-alanine exporter AlaE	alaE	-	-	-	-	-	-	-	-	-	-	-	AlaE
k141_4875_1	1265505.ATUG01000003_gene777	1.24e-44	156.0	COG2221@1|root,COG2221@2|Bacteria,1R5F8@1224|Proteobacteria,42PB3@68525|delta/epsilon subdivisions,2WKJR@28221|Deltaproteobacteria,2MHQY@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Proto-chlorophyllide reductase 57 kD subunit	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_6,Fer4_7,NIR_SIR,PCP_red
k141_3836_1	1219080.VEZ01S_44_00340	3.47e-56	185.0	2AWRT@1|root,31NNS@2|Bacteria,1QKDC@1224|Proteobacteria,1TIH1@1236|Gammaproteobacteria,1XZ3Z@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_500_2	933262.AXAM01000008_gene1947	4.84e-100	303.0	COG0324@1|root,COG0324@2|Bacteria,1MUB2@1224|Proteobacteria,42M7V@68525|delta/epsilon subdivisions,2WIUB@28221|Deltaproteobacteria,2MIV4@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
k141_500_3	555779.Dthio_PD0916	1.92e-21	95.5	COG1148@1|root,COG4231@1|root,COG1148@2|Bacteria,COG4231@2|Bacteria,1QUM4@1224|Proteobacteria,42MPP@68525|delta/epsilon subdivisions,2WJ3U@28221|Deltaproteobacteria,2M7SC@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	4Fe-4S ferredoxin iron-sulfur binding domain protein	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_7,Pyr_redox_2
k141_500_4	1304885.AUEY01000026_gene3545	0.0	1322.0	COG1148@1|root,COG1148@2|Bacteria,1QUM4@1224|Proteobacteria,42MPP@68525|delta/epsilon subdivisions,2WJ3U@28221|Deltaproteobacteria,2MIA4@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_20,Fer4_7,Pyr_redox_2
k141_500_5	1265505.ATUG01000003_gene388	9.11e-18	75.5	COG1908@1|root,COG1908@2|Bacteria,1NGSG@1224|Proteobacteria,42XN0@68525|delta/epsilon subdivisions,2WTGE@28221|Deltaproteobacteria,2MM9B@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Methyl-viologen-reducing hydrogenase, delta subunit	-	-	-	-	-	-	-	-	-	-	-	-	FlpD
k141_4545_2	367737.Abu_0661	1.44e-224	627.0	COG0677@1|root,COG0677@2|Bacteria,1MUC6@1224|Proteobacteria,42M4F@68525|delta/epsilon subdivisions,2YMAG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	-	-	-	ko:K02474	ko00520,map00520	-	R06894	RC00291	ko00000,ko00001,ko01000,ko01005	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
k141_4545_3	572480.Arnit_2572	3e-208	582.0	COG0451@1|root,COG0451@2|Bacteria,1MU7J@1224|Proteobacteria,42MWH@68525|delta/epsilon subdivisions,2YMPE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	epimerase dehydratase family	-	-	5.1.3.2,5.1.3.6	ko:K01784,ko:K08679	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R01385,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
k141_4545_4	909663.KI867150_gene1972	1.31e-63	224.0	COG0438@1|root,COG0457@1|root,COG0463@1|root,COG1215@1|root,COG1216@1|root,COG4627@1|root,COG0438@2|Bacteria,COG0457@2|Bacteria,COG0463@2|Bacteria,COG1215@2|Bacteria,COG1216@2|Bacteria,COG4627@2|Bacteria,1MWYH@1224|Proteobacteria,42Q22@68525|delta/epsilon subdivisions,2WK61@28221|Deltaproteobacteria,2MRSD@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1,TPR_16,TPR_8
k141_501_1	316067.Geob_3313	1.49e-42	160.0	COG1305@1|root,COG1305@2|Bacteria,1PEH8@1224|Proteobacteria	1224|Proteobacteria	E	Transglutaminase-like	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
k141_4877_2	1120705.FG95_00453	2.84e-35	138.0	COG0612@1|root,COG0612@2|Bacteria,1NAH6@1224|Proteobacteria,2U0S5@28211|Alphaproteobacteria,2K0JT@204457|Sphingomonadales	204457|Sphingomonadales	S	Belongs to the peptidase M16 family	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
k141_4154_1	314345.SPV1_00150	1.88e-28	105.0	COG1917@1|root,COG1917@2|Bacteria,1RDGQ@1224|Proteobacteria	1224|Proteobacteria	S	Catalyzes the circularization of gamma-N-acetyl- alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6- tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant	ectC	-	4.2.1.108	ko:K06720	ko00260,ko01100,ko01120,map00260,map01100,map01120	M00033	R06979	RC01729	ko00000,ko00001,ko00002,ko01000	-	-	-	Ectoine_synth
k141_4154_2	96561.Dole_0961	1.28e-243	676.0	COG0160@1|root,COG0160@2|Bacteria,1MWY6@1224|Proteobacteria,42N1V@68525|delta/epsilon subdivisions,2WKME@28221|Deltaproteobacteria,2MMQX@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.76	ko:K00836	ko00260,ko01100,ko01120,ko01210,ko01230,map00260,map01100,map01120,map01210,map01230	M00033	R06977	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
k141_4154_3	1246626.BleG1_0293	6.01e-38	134.0	COG0454@1|root,COG0456@2|Bacteria,1V4R5@1239|Firmicutes,4HGWU@91061|Bacilli,1ZFWX@1386|Bacillus	91061|Bacilli	K	L-2,4-diaminobutyric acid acetyltransferase	ectA	-	2.3.1.178	ko:K06718	ko00260,ko01100,ko01120,map00260,map01100,map01120	M00033	R06978	RC00004,RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetyltransf_1
k141_1129_1	1321778.HMPREF1982_00038	3.71e-84	252.0	29YU0@1|root,30KQB@2|Bacteria,1VUYA@1239|Firmicutes,250G4@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_1129_2	588581.Cpap_3474	1e-18	92.4	COG0310@1|root,COG0310@2|Bacteria,1TPEN@1239|Firmicutes,248S9@186801|Clostridia,3WHIW@541000|Ruminococcaceae	186801|Clostridia	P	PFAM cobalamin (vitamin B12) biosynthesis CbiM protein	-	-	-	ko:K02007	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	CbiM,PDGLE
k141_4546_1	674977.VMC_14570	5.4e-06	52.4	COG1596@1|root,COG1596@2|Bacteria,1N7GP@1224|Proteobacteria,1RQSM@1236|Gammaproteobacteria,1XUWY@135623|Vibrionales	135623|Vibrionales	M	Periplasmic protein involved in polysaccharide export	-	-	-	-	-	-	-	-	-	-	-	-	Poly_export,SLBB
k141_4546_2	1121396.KB892951_gene2953	8.14e-146	432.0	COG1086@1|root,COG1086@2|Bacteria,1MWKY@1224|Proteobacteria,42MMR@68525|delta/epsilon subdivisions,2WJEB@28221|Deltaproteobacteria,2MJ3Q@213118|Desulfobacterales	28221|Deltaproteobacteria	GM	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	CoA_binding_3,Polysacc_synt_2
k141_4878_1	1232410.KI421415_gene3054	7.02e-78	253.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42NUF@68525|delta/epsilon subdivisions,2WK2F@28221|Deltaproteobacteria,43TB2@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Sigma-54 interaction domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Sigma54_activat
k141_4155_1	879212.DespoDRAFT_03277	8.62e-55	179.0	COG0024@1|root,COG0024@2|Bacteria,1MU99@1224|Proteobacteria,42MM5@68525|delta/epsilon subdivisions,2WJMN@28221|Deltaproteobacteria,2MIBA@213118|Desulfobacterales	28221|Deltaproteobacteria	J	TIGRFAM methionine aminopeptidase, type I	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24,SEC-C
k141_5242_2	264951.V5GAE8	4.41e-06	53.1	KOG4781@1|root,KOG4781@2759|Eukaryota,3A30J@33154|Opisthokonta,3P3MC@4751|Fungi,3QUYQ@4890|Ascomycota,20GR0@147545|Eurotiomycetes,3S7V5@5042|Eurotiales	4751|Fungi	S	thioesterase family	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
k141_5242_3	879212.DespoDRAFT_02402	9.36e-106	321.0	COG1752@1|root,COG1752@2|Bacteria,1MU6Z@1224|Proteobacteria,42N0D@68525|delta/epsilon subdivisions,2WK3S@28221|Deltaproteobacteria,2MII2@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Esterase of the alpha-beta hydrolase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Patatin
k141_5242_4	933262.AXAM01000038_gene895	6.46e-101	300.0	COG0846@1|root,COG0846@2|Bacteria,1MUK1@1224|Proteobacteria,42R4A@68525|delta/epsilon subdivisions,2WM9Z@28221|Deltaproteobacteria,2MJDE@213118|Desulfobacterales	28221|Deltaproteobacteria	K	PFAM Silent information regulator protein Sir2	-	-	-	ko:K12410	-	-	-	-	ko00000,ko01000	-	-	-	SIR2
k141_5242_5	1307759.JOMJ01000004_gene2687	1.29e-94	287.0	COG1235@1|root,COG1235@2|Bacteria,1NW4Z@1224|Proteobacteria,42PTI@68525|delta/epsilon subdivisions,2WIWT@28221|Deltaproteobacteria,2M93E@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
k141_327_1	1304284.L21TH_1081	1.68e-104	314.0	COG2025@1|root,COG2025@2|Bacteria,1TPC8@1239|Firmicutes,247NF@186801|Clostridia,36DD9@31979|Clostridiaceae	186801|Clostridia	C	Electron transfer flavoprotein	etfA2	-	-	ko:K03522	-	-	-	-	ko00000,ko04147	-	-	-	ETF,ETF_alpha
k141_1957_1	1121403.AUCV01000018_gene3223	4.33e-123	356.0	COG0834@1|root,COG0834@2|Bacteria,1MV3Q@1224|Proteobacteria,42MKG@68525|delta/epsilon subdivisions,2WJQ7@28221|Deltaproteobacteria	28221|Deltaproteobacteria	ET	PFAM Extracellular solute-binding protein, family 3	glnH	-	-	ko:K10036	ko02010,map02010	M00227	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3.2	-	-	SBP_bac_3
k141_2293_1	1116375.VEJY3_08600	6.85e-57	184.0	COG1082@1|root,COG1082@2|Bacteria,1NFRG@1224|Proteobacteria,1RPT9@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	Sugar phosphate isomerases epimerases	iolH	-	-	ko:K06605	-	-	-	-	ko00000	-	-	-	AP_endonuc_2
k141_2293_2	1116375.VEJY3_08595	1.06e-58	195.0	COG0477@1|root,COG2814@2|Bacteria,1MVKJ@1224|Proteobacteria,1RMHJ@1236|Gammaproteobacteria,1XUMU@135623|Vibrionales	135623|Vibrionales	P	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family	-	-	-	ko:K08138	-	-	-	-	ko00000,ko02000	2.A.1.1.3	-	-	Sugar_tr
k141_4659_1	717772.THIAE_06495	3.47e-12	72.0	COG0188@1|root,COG0188@2|Bacteria,1MURI@1224|Proteobacteria,1RMTC@1236|Gammaproteobacteria,45ZVK@72273|Thiotrichales	72273|Thiotrichales	L	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule	parC	-	-	ko:K02621	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
k141_4659_2	502025.Hoch_6827	1.84e-12	70.9	COG2204@1|root,COG2204@2|Bacteria,1QW1J@1224|Proteobacteria,43BRH@68525|delta/epsilon subdivisions,2X72C@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	PFAM response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388,Response_reg
k141_2532_1	373994.Riv7116_3253	2.04e-73	237.0	COG0146@1|root,COG0146@2|Bacteria,1GCWJ@1117|Cyanobacteria,1HKJM@1161|Nostocales	1117|Cyanobacteria	EQ	PFAM Hydantoinase B oxoprolinase	-	-	3.5.2.14	ko:K01474	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydantoinase_B
k141_856_1	563192.HMPREF0179_00289	3.76e-16	77.4	COG1988@1|root,COG1988@2|Bacteria,1RBHW@1224|Proteobacteria,43059@68525|delta/epsilon subdivisions,2WV8K@28221|Deltaproteobacteria,2MBS1@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	LexA-binding, inner membrane-associated putative hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	YdjM
k141_4282_1	55601.VANGNB10_cI1668c	4.86e-115	335.0	COG0811@1|root,COG0811@2|Bacteria,1NCWW@1224|Proteobacteria,1RMD4@1236|Gammaproteobacteria,1XUNH@135623|Vibrionales	135623|Vibrionales	U	COG0811 Biopolymer transport proteins	tolQ	-	-	ko:K03562	ko01120,map01120	-	-	-	ko00000,ko02000	1.A.30.2.2	-	-	MotA_ExbB
k141_4282_2	1051646.VITU9109_12892	1.34e-52	171.0	COG0824@1|root,COG0824@2|Bacteria,1MZH6@1224|Proteobacteria,1S93F@1236|Gammaproteobacteria,1XXKJ@135623|Vibrionales	135623|Vibrionales	S	Thioesterase-like superfamily	ybgC	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT
k141_4282_3	796620.VIBC2010_09527	2.85e-28	105.0	COG3790@1|root,COG3790@2|Bacteria,1MZDH@1224|Proteobacteria,1SA3Q@1236|Gammaproteobacteria,1XXY3@135623|Vibrionales	135623|Vibrionales	S	Cyd operon protein YbgE	-	-	-	-	-	-	-	-	-	-	-	-	Cyd_oper_YbgE
k141_4282_4	316275.VSAL_I1892	4.83e-17	72.4	COG4890@1|root,COG4890@2|Bacteria,1NGDQ@1224|Proteobacteria,1SGGW@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Cyd operon protein YbgT	ybgT	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0008152,GO:0016020,GO:0016021,GO:0016491,GO:0016679,GO:0019867,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0055114,GO:0071944	1.10.3.14	ko:K00424	ko00190,ko02020,map00190,map02020	M00153	-	-	ko00000,ko00001,ko01000	3.D.4.3	-	-	YbgT_YccB
k141_4282_5	55601.VANGNB10_cI1671c	2.34e-213	596.0	COG1294@1|root,COG1294@2|Bacteria,1MURP@1224|Proteobacteria,1RP7F@1236|Gammaproteobacteria,1XVFM@135623|Vibrionales	135623|Vibrionales	C	COG1294 Cytochrome bd-type quinol oxidase, subunit 2	cydB	-	1.10.3.14	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	Cyt_bd_oxida_II
k141_3955_1	1265505.ATUG01000001_gene2994	6.49e-126	367.0	COG1089@1|root,COG1089@2|Bacteria,1MUX0@1224|Proteobacteria,42KZY@68525|delta/epsilon subdivisions,2WJ4B@28221|Deltaproteobacteria,2MJ21@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose	gmd	-	4.2.1.47	ko:K01711	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R00888	RC00402	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
k141_2853_1	29495.EA26_11265	3.71e-93	291.0	COG0738@1|root,COG0738@2|Bacteria,1QUEB@1224|Proteobacteria,1T1VW@1236|Gammaproteobacteria,1XT1X@135623|Vibrionales	135623|Vibrionales	G	of the major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
k141_2853_2	1123518.ARWI01000001_gene694	3.58e-85	263.0	2DBB6@1|root,2Z85M@2|Bacteria,1QMDX@1224|Proteobacteria,1RZPX@1236|Gammaproteobacteria,461IY@72273|Thiotrichales	72273|Thiotrichales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_2853_3	794903.OPIT5_11920	1.12e-28	109.0	COG0169@1|root,COG0169@2|Bacteria,46UXP@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Shikimate dehydrogenase substrate binding domain	-	-	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	-	Shikimate_dh_N
k141_4283_1	177437.HRM2_45220	5.36e-33	123.0	COG0798@1|root,COG0798@2|Bacteria,1MUXY@1224|Proteobacteria,42M0Z@68525|delta/epsilon subdivisions,2WK36@28221|Deltaproteobacteria,2MJ5F@213118|Desulfobacterales	28221|Deltaproteobacteria	P	PFAM Bile acid sodium symporter	arsB	-	-	ko:K03325	-	-	-	-	ko00000,ko02000	2.A.59	-	-	SBF
k141_4283_2	177437.HRM2_07790	3.18e-62	206.0	COG0471@1|root,COG0471@2|Bacteria,1MUSA@1224|Proteobacteria,42MAP@68525|delta/epsilon subdivisions,2WIYI@28221|Deltaproteobacteria,2MJA8@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Sodium:sulfate symporter transmembrane region	sdcS	-	-	ko:K14445	-	-	-	-	ko00000,ko02000	2.A.47.1	-	-	Na_sulph_symp
k141_331_2	933262.AXAM01000010_gene1351	7.47e-108	327.0	COG0552@1|root,COG0552@2|Bacteria,1MUDU@1224|Proteobacteria,42N3Z@68525|delta/epsilon subdivisions,2WIPM@28221|Deltaproteobacteria,2MITD@213118|Desulfobacterales	28221|Deltaproteobacteria	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components	ftsY	-	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
k141_331_3	177437.HRM2_07210	2.13e-15	76.6	COG0385@1|root,COG0385@2|Bacteria,1MUMM@1224|Proteobacteria,42S6Y@68525|delta/epsilon subdivisions,2WNZA@28221|Deltaproteobacteria,2MJV1@213118|Desulfobacterales	28221|Deltaproteobacteria	S	SBF-like CPA transporter family (DUF4137)	-	-	-	ko:K14347	-	-	-	-	ko00000,ko02000,ko04147	2.A.93.1	-	-	SBF_like
k141_3248_1	1232437.KL662020_gene662	6.81e-12	63.2	COG1942@1|root,COG1942@2|Bacteria,1NAGG@1224|Proteobacteria,42SUX@68525|delta/epsilon subdivisions,2WPAH@28221|Deltaproteobacteria,2MK8R@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Tautomerase enzyme	-	-	5.3.2.6	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	M00569	R03966,R05389	RC01040,RC01355	ko00000,ko00001,ko00002,ko01000	-	-	-	Tautomerase
k141_3248_2	1168289.AJKI01000046_gene910	3.63e-76	270.0	COG1538@1|root,COG1538@2|Bacteria,4NHGK@976|Bacteroidetes	976|Bacteroidetes	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC_sub_bind,OEP
k141_3248_3	266264.Rmet_1943	5.49e-37	147.0	COG0845@1|root,COG0845@2|Bacteria,1NJDF@1224|Proteobacteria,2VIS6@28216|Betaproteobacteria,1K1ID@119060|Burkholderiaceae	28216|Betaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
k141_4660_1	644801.Psest_3229	6.81e-15	86.7	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,1Z2CU@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	NT	Methyl-accepting chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal,dCache_1,dCache_2,sCache_2
k141_4660_2	1298593.TOL_0762	2.47e-13	67.8	COG0834@1|root,COG0834@2|Bacteria,1RHMR@1224|Proteobacteria	1224|Proteobacteria	ET	ABC-type amino acid transport signal transduction systems periplasmic component domain	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_4286_1	570967.JMLV01000009_gene1011	4.81e-121	369.0	COG4166@1|root,COG4166@2|Bacteria,1MUVU@1224|Proteobacteria,2TQJX@28211|Alphaproteobacteria,2JQ6J@204441|Rhodospirillales	204441|Rhodospirillales	E	COG4166 ABC-type oligopeptide transport system, periplasmic component	-	-	-	ko:K13893	ko02010,map02010	M00349	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.21,3.A.1.5.24	-	-	SBP_bac_5
k141_1280_2	1195236.CTER_3582	2e-34	147.0	COG0840@1|root,COG0840@2|Bacteria,1TP5A@1239|Firmicutes,247S3@186801|Clostridia	186801|Clostridia	NT	methyl-accepting chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal,dCache_1
k141_332_1	1379858.N508_00956	9.53e-19	95.1	294BG@1|root,2ZRRP@2|Bacteria,2GGKW@200930|Deferribacteres	200930|Deferribacteres	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_2533_1	290317.Cpha266_1072	9.8e-114	336.0	COG0454@1|root,COG0454@2|Bacteria	2|Bacteria	K	-acetyltransferase	-	-	2.3.1.59	ko:K17840	-	-	-	-	br01600,ko00000,ko01000,ko01504	-	-	-	Acetyltransf_1,Acetyltransf_10
k141_2533_2	331678.Cphamn1_0510	6.59e-155	439.0	COG0428@1|root,COG0428@2|Bacteria,1FEX5@1090|Chlorobi	1090|Chlorobi	P	PFAM zinc iron permease	-	-	-	ko:K07238	-	-	-	-	ko00000,ko02000	2.A.5.5	-	-	Zip
k141_2533_3	159087.Daro_3017	4.17e-38	152.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2VHTK@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	DUF3365,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_8,Response_reg
k141_857_4	674977.VMC_02000	5e-261	721.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,1RMWA@1236|Gammaproteobacteria,1XTC7@135623|Vibrionales	135623|Vibrionales	JKL	DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA	rhlB	GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009056,GO:0009057,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019439,GO:0034641,GO:0034655,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360,GO:1901361,GO:1901575	3.6.4.13	ko:K03732	ko03018,map03018	M00394	-	-	ko00000,ko00001,ko00002,ko01000,ko03019	-	-	-	DEAD,Helicase_C
k141_4288_1	1121422.AUMW01000009_gene3305	2.8e-115	341.0	COG1250@1|root,COG1250@2|Bacteria,1TPJS@1239|Firmicutes,248AE@186801|Clostridia,266V3@186807|Peptococcaceae	186801|Clostridia	I	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain	-	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
k141_3657_1	1348635.BBJY01000021_gene2848	0.0	1140.0	COG3164@1|root,COG3164@2|Bacteria,1MXWF@1224|Proteobacteria,1RNUK@1236|Gammaproteobacteria,1XTHT@135623|Vibrionales	135623|Vibrionales	S	Protein of unknown function	VV2929	-	-	-	-	-	-	-	-	-	-	-	AsmA_2,DUF3971
k141_3657_3	29495.EA26_18995	3.47e-74	224.0	COG3076@1|root,COG3076@2|Bacteria,1RDKS@1224|Proteobacteria,1S4A6@1236|Gammaproteobacteria,1XWVQ@135623|Vibrionales	135623|Vibrionales	S	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome	rraB	-	-	ko:K09893	-	-	-	-	ko00000,ko03019	-	-	-	RraB
k141_3657_4	345073.VC395_0469	3.31e-58	188.0	COG3250@1|root,COG3250@2|Bacteria,1NYBH@1224|Proteobacteria,1RZPC@1236|Gammaproteobacteria,1XSPV@135623|Vibrionales	135623|Vibrionales	G	COG3250 Beta-galactosidase beta-glucuronidase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_2_N
k141_606_2	400668.Mmwyl1_2693	5.96e-116	351.0	COG1367@1|root,COG1367@2|Bacteria,1RDSA@1224|Proteobacteria,1SAUT@1236|Gammaproteobacteria,1XQFS@135619|Oceanospirillales	135619|Oceanospirillales	L	RAMP superfamily	-	-	-	ko:K07061	-	-	-	-	ko00000,ko02048	-	-	-	RAMPs
k141_606_3	400668.Mmwyl1_2692	0.0	884.0	COG1353@1|root,COG1353@2|Bacteria,1RC0I@1224|Proteobacteria,1RZFT@1236|Gammaproteobacteria,1XPY9@135619|Oceanospirillales	135619|Oceanospirillales	S	CRISPR-associated protein Crm2	-	-	-	ko:K19076	-	-	-	-	ko00000,ko02048	-	-	-	DUF3692
k141_606_4	400668.Mmwyl1_2691	1.04e-211	593.0	COG1769@1|root,COG1769@2|Bacteria,1RJEB@1224|Proteobacteria,1SAQ0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	crispr-associated protein	-	-	-	ko:K09127	-	-	-	-	ko00000,ko02048	-	-	-	Cas_Cmr3
k141_606_5	400668.Mmwyl1_2690	2.05e-153	436.0	COG1336@1|root,COG1336@2|Bacteria,1RE1Y@1224|Proteobacteria,1S9QP@1236|Gammaproteobacteria,1XQ3W@135619|Oceanospirillales	135619|Oceanospirillales	L	CRISPR-associated RAMP	-	-	-	ko:K09000	-	-	-	-	ko00000,ko02048	-	-	-	RAMPs
k141_606_6	400668.Mmwyl1_2689	1.81e-64	200.0	COG3337@1|root,COG3337@2|Bacteria,1NZUM@1224|Proteobacteria,1SRYF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	crispr-associated protein	-	-	-	ko:K19141	-	-	-	-	ko00000,ko02048	-	-	-	Cas_Cmr5
k141_606_7	400668.Mmwyl1_2688	1.83e-179	509.0	COG1604@1|root,COG1604@2|Bacteria,1REU6@1224|Proteobacteria,1SFMS@1236|Gammaproteobacteria,1XQHB@135619|Oceanospirillales	135619|Oceanospirillales	L	RAMP superfamily	-	-	-	ko:K19142	-	-	-	-	ko00000,ko02048	-	-	-	RAMPs
k141_606_9	357804.Ping_1400	8.04e-46	157.0	2CJUF@1|root,32RVU@2|Bacteria,1RE4Q@1224|Proteobacteria,1S3VX@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	crispr-associated protein, csy4	cas6f	-	-	ko:K19130	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	Cas_Csy4
k141_2535_1	522772.Dacet_1285	4.6e-38	137.0	2E00X@1|root,32VQ9@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_2294_1	555088.DealDRAFT_0829	1.13e-62	220.0	COG1574@1|root,COG1574@2|Bacteria,1TQ6G@1239|Firmicutes,24A5F@186801|Clostridia,42KS4@68298|Syntrophomonadaceae	186801|Clostridia	S	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
k141_2294_2	177437.HRM2_37430	3.72e-111	326.0	COG1024@1|root,COG1024@2|Bacteria,1RIVB@1224|Proteobacteria,42PMV@68525|delta/epsilon subdivisions,2WKCQ@28221|Deltaproteobacteria,2MHM8@213118|Desulfobacterales	28221|Deltaproteobacteria	I	PFAM Enoyl-CoA hydratase isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
k141_2294_4	1304885.AUEY01000036_gene2252	3.62e-121	369.0	COG3864@1|root,COG3864@2|Bacteria,1R58X@1224|Proteobacteria,42NAE@68525|delta/epsilon subdivisions,2WMCZ@28221|Deltaproteobacteria,2MJAT@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Putative metallopeptidase domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF2201,DUF2201_N
k141_2294_5	1304885.AUEY01000036_gene2253	3.34e-101	307.0	COG0714@1|root,COG0714@2|Bacteria,1PHW4@1224|Proteobacteria,42QA8@68525|delta/epsilon subdivisions,2WJBW@28221|Deltaproteobacteria,2MIKF@213118|Desulfobacterales	28221|Deltaproteobacteria	S	PFAM ATPase associated with various cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	AAA_3,AAA_5
k141_4289_1	1121396.KB892913_gene170	7.46e-98	326.0	COG0304@1|root,COG1028@1|root,COG2070@1|root,COG3321@1|root,COG0304@2|Bacteria,COG1028@2|Bacteria,COG2070@2|Bacteria,COG3321@2|Bacteria,1R89Z@1224|Proteobacteria,42NGA@68525|delta/epsilon subdivisions,2WJK3@28221|Deltaproteobacteria,2MIK4@213118|Desulfobacterales	28221|Deltaproteobacteria	IQ	Beta-ketoacyl synthase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_1,KAsynt_C_assoc,KR,Ketoacyl-synt_C,NMO,PP-binding,PS-DH,ketoacyl-synt
k141_2295_1	1232437.KL661985_gene3582	8.62e-100	300.0	COG0765@1|root,COG0765@2|Bacteria,1MV3I@1224|Proteobacteria,42PDT@68525|delta/epsilon subdivisions,2WKER@28221|Deltaproteobacteria,2MIIP@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K09971	ko02010,map02010	M00232	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3.18,3.A.1.3.7,3.A.1.3.8	-	-	BPD_transp_1
k141_858_1	177437.HRM2_30480	1.54e-35	125.0	COG1664@1|root,COG1664@2|Bacteria,1QN6Q@1224|Proteobacteria,42SWT@68525|delta/epsilon subdivisions,2WPH2@28221|Deltaproteobacteria,2MK42@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Polymer-forming cytoskeletal	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
k141_858_2	96561.Dole_2202	1.53e-154	463.0	COG3608@1|root,COG3608@2|Bacteria,1Q5G3@1224|Proteobacteria,42MSH@68525|delta/epsilon subdivisions,2WKM8@28221|Deltaproteobacteria,2MKPY@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Carboxypeptidase controlling helical cell shape catalytic	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M99,Peptidase_M99_C
k141_4290_2	351627.Csac_1662	2.54e-11	62.0	COG2747@1|root,COG2747@2|Bacteria,1VKDG@1239|Firmicutes,24UWF@186801|Clostridia,42IWP@68295|Thermoanaerobacterales	186801|Clostridia	KNU	PFAM Anti-sigma-28 factor FlgM family protein	-	-	-	ko:K02398	ko02020,ko02025,ko02026,ko02040,map02020,map02025,map02026,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FlgM
k141_4661_1	177437.HRM2_12090	3.63e-19	84.7	2AKAT@1|root,31B1G@2|Bacteria,1N656@1224|Proteobacteria,42T13@68525|delta/epsilon subdivisions,2WPIE@28221|Deltaproteobacteria,2MKB7@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_4661_2	439235.Dalk_2529	1.35e-79	260.0	COG4191@1|root,COG4191@2|Bacteria,1MY12@1224|Proteobacteria,42PID@68525|delta/epsilon subdivisions,2WJVW@28221|Deltaproteobacteria,2MI1P@213118|Desulfobacterales	28221|Deltaproteobacteria	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_9
k141_4661_3	1121405.dsmv_0048	5.57e-191	546.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WJF9@28221|Deltaproteobacteria,2MHRZ@213118|Desulfobacterales	28221|Deltaproteobacteria	T	response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
k141_4661_4	269799.Gmet_1926	4.97e-28	111.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,42MMK@68525|delta/epsilon subdivisions,2WJC1@28221|Deltaproteobacteria,43RZT@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	ABC transporter	yjjK	-	3.6.3.25	ko:K06020	-	-	-	-	ko00000,ko01000	-	-	-	ABC_tran,ABC_tran_Xtn
k141_859_2	879212.DespoDRAFT_03511	3.32e-24	100.0	COG0010@1|root,COG0010@2|Bacteria,1MVFH@1224|Proteobacteria,42MXZ@68525|delta/epsilon subdivisions,2WJWG@28221|Deltaproteobacteria,2MIZR@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Arginase family	-	-	3.5.3.1	ko:K01476	ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146	M00029,M00134	R00551	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
k141_1553_10	1121289.JHVL01000010_gene1344	2.64e-181	523.0	COG0651@1|root,COG0651@2|Bacteria,1TRAT@1239|Firmicutes,24AZH@186801|Clostridia,36E6V@31979|Clostridiaceae	186801|Clostridia	CP	Proton-conducting membrane transporter	-	-	-	ko:K05568,ko:K12141	-	-	-	-	ko00000,ko01000,ko02000	2.A.63.1,2.A.63.2	-	-	Proton_antipo_M,Proton_antipo_N
k141_1553_11	1286171.EAL2_808p03210	8.96e-51	163.0	COG1006@1|root,COG1006@2|Bacteria,1VBKW@1239|Firmicutes,24IY8@186801|Clostridia	186801|Clostridia	P	PFAM NADH-ubiquinone oxidoreductase chain 4L	-	-	-	ko:K05567	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	Oxidored_q2
k141_1553_12	1230342.CTM_07296	5.71e-57	181.0	COG2111@1|root,COG2111@2|Bacteria,1V6XC@1239|Firmicutes,25DGN@186801|Clostridia,36UB0@31979|Clostridiaceae	186801|Clostridia	P	Domain related to MnhB subunit of Na+/H+ antiporter	-	-	-	ko:K05566	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	MnhB
k141_1553_13	1121324.CLIT_14c00330	2.94e-30	110.0	COG2111@1|root,COG2111@2|Bacteria,1VQK1@1239|Firmicutes,25DGP@186801|Clostridia	186801|Clostridia	P	Na H antiporter	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_1553_14	1121289.JHVL01000010_gene1348	2.32e-28	103.0	COG1563@1|root,COG1563@2|Bacteria,1VGXY@1239|Firmicutes,24SS2@186801|Clostridia,36MD6@31979|Clostridiaceae	186801|Clostridia	P	Domain of unknown function (DUF4040)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4040
k141_1553_15	411902.CLOBOL_02361	2.85e-14	69.7	COG1320@1|root,COG1320@2|Bacteria,1U2CE@1239|Firmicutes,259WY@186801|Clostridia,222W4@1506553|Lachnoclostridium	186801|Clostridia	P	Na+/H+ antiporter subunit	-	-	-	-	-	-	-	-	-	-	-	-	PhaG_MnhG_YufB
k141_1553_16	1121289.JHVL01000010_gene1350	1.26e-28	105.0	COG2212@1|root,COG2212@2|Bacteria,1VENR@1239|Firmicutes,24N3X@186801|Clostridia,36MD1@31979|Clostridiaceae	186801|Clostridia	P	Multiple resistance and pH regulation protein F (MrpF / PhaF)	-	-	-	ko:K05570	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	MrpF_PhaF
k141_1553_17	555088.DealDRAFT_2490	2.84e-14	72.0	COG1863@1|root,COG1863@2|Bacteria,1VEJ0@1239|Firmicutes,24REY@186801|Clostridia	186801|Clostridia	P	PFAM cation antiporter	-	-	-	ko:K05569	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	MNHE
k141_1553_19	1121324.CLIT_23c00150	2.43e-276	779.0	COG3284@1|root,COG3284@2|Bacteria,1VHQN@1239|Firmicutes,25EB0@186801|Clostridia,25UPX@186804|Peptostreptococcaceae	186801|Clostridia	K	Bacterial regulatory protein, Fis family	-	-	-	ko:K21405	-	-	-	-	ko00000,ko03000	-	-	-	GAF,HTH_8,PAS,PAS_9,Sigma54_activat
k141_1553_20	1395571.TMS3_0115430	4.79e-07	59.3	COG2199@1|root,COG3706@2|Bacteria,1N9PI@1224|Proteobacteria,1RPY9@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,dCache_1
k141_1553_21	536233.CLO_0219	7e-14	66.6	COG2608@1|root,COG2608@2|Bacteria,1VK5F@1239|Firmicutes,24RMA@186801|Clostridia,36P1S@31979|Clostridiaceae	186801|Clostridia	P	Heavy metal transport detoxification protein	copZ	-	-	ko:K07213	ko04978,map04978	-	-	-	ko00000,ko00001	-	-	-	HMA
k141_1553_22	521460.Athe_2280	1.27e-280	800.0	COG2217@1|root,COG2217@2|Bacteria,1TP5S@1239|Firmicutes,247MW@186801|Clostridia,42EQF@68295|Thermoanaerobacterales	186801|Clostridia	P	Heavy metal transport detoxification protein	copA	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
k141_1553_23	1158607.UAU_02227	2.14e-09	62.8	COG1309@1|root,COG1309@2|Bacteria,1TWE4@1239|Firmicutes,4I43W@91061|Bacilli,4B1WK@81852|Enterococcaceae	91061|Bacilli	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
k141_1553_24	386415.NT01CX_1548	2.54e-37	147.0	COG0845@1|root,COG0845@2|Bacteria,1V3TH@1239|Firmicutes,24AAF@186801|Clostridia,36FC9@31979|Clostridiaceae	186801|Clostridia	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
k141_1553_25	1121324.CLIT_10c05110	0.0	1006.0	COG0841@1|root,COG0841@2|Bacteria,1TQ03@1239|Firmicutes,2491S@186801|Clostridia,25QT4@186804|Peptostreptococcaceae	186801|Clostridia	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	nolG2	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k141_1553_26	985665.HPL003_18205	1.4e-39	135.0	COG2204@1|root,COG2204@2|Bacteria,1UHXE@1239|Firmicutes,4ISDB@91061|Bacilli,26XDQ@186822|Paenibacillaceae	91061|Bacilli	T	Chemotaxis protein CheY	cheY	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
k141_1553_27	1499683.CCFF01000015_gene3522	3.84e-77	236.0	COG0461@1|root,COG0461@2|Bacteria,1V1BZ@1239|Firmicutes,25CGM@186801|Clostridia,36FPJ@31979|Clostridiaceae	186801|Clostridia	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	pyrE	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran
k141_1553_28	1476973.JMMB01000007_gene430	1.57e-138	400.0	COG0167@1|root,COG0167@2|Bacteria,1TPFV@1239|Firmicutes,248CQ@186801|Clostridia,25QCB@186804|Peptostreptococcaceae	186801|Clostridia	F	Catalyzes the conversion of dihydroorotate to orotate	pyrD	-	1.3.1.14	ko:K17828	ko00240,ko01100,map00240,map01100	M00051	R01869	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
k141_1553_29	478749.BRYFOR_05308	5.37e-67	214.0	COG0543@1|root,COG0543@2|Bacteria,1TQ5D@1239|Firmicutes,24AY2@186801|Clostridia	186801|Clostridia	C	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(	pyrK	-	-	ko:K02823	ko00240,ko01100,map00240,map01100	-	-	-	ko00000,ko00001	-	-	iHN637.CLJU_RS17580	DHODB_Fe-S_bind,NAD_binding_1
k141_1424_22	1280694.AUJQ01000006_gene900	5.89e-71	226.0	COG1606@1|root,COG1606@2|Bacteria,1TPB2@1239|Firmicutes,2485J@186801|Clostridia,3NGD0@46205|Pseudobutyrivibrio	186801|Clostridia	S	TIGR00268 family	-	-	-	ko:K06864	-	-	-	-	ko00000	-	-	-	ATP_bind_3,NAD_synthase,QueC
k141_1424_23	1121289.JHVL01000001_gene1957	1.21e-30	110.0	2DMMF@1|root,32SEK@2|Bacteria,1VAB3@1239|Firmicutes,24N8S@186801|Clostridia,36MIU@31979|Clostridiaceae	186801|Clostridia	S	Uncharacterized protein conserved in bacteria (DUF2325)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2325
k141_1424_24	1230342.CTM_13758	1.4e-13	66.2	COG1918@1|root,COG1918@2|Bacteria,1TV62@1239|Firmicutes,24X6Y@186801|Clostridia	186801|Clostridia	P	FeoA	-	-	-	-	-	-	-	-	-	-	-	-	FeoA
k141_1424_25	272623.L192240	6.9e-21	87.0	COG1918@1|root,COG1918@2|Bacteria,1VEHC@1239|Firmicutes,4HPFS@91061|Bacilli,1YBWC@1357|Lactococcus	91061|Bacilli	P	FeoA	feoA	-	-	ko:K04758	-	-	-	-	ko00000,ko02000	-	-	-	FeoA
k141_1424_26	1121289.JHVL01000001_gene1959	1.87e-307	859.0	COG0370@1|root,COG0370@2|Bacteria,1TP7E@1239|Firmicutes,24885@186801|Clostridia,36DF0@31979|Clostridiaceae	186801|Clostridia	P	transporter of a GTP-driven Fe(2 ) uptake system	-	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoB_C,FeoB_N,Gate
k141_1424_27	66692.ABC3543	1.51e-06	52.8	2A6G4@1|root,30V95@2|Bacteria,1UCGY@1239|Firmicutes,4INZB@91061|Bacilli,1ZP5K@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_1424_28	1304284.L21TH_0752	1.38e-94	284.0	COG2188@1|root,COG2188@2|Bacteria,1TRF6@1239|Firmicutes,249CC@186801|Clostridia,36EWV@31979|Clostridiaceae	186801|Clostridia	K	trehalose operon repressor	treR	-	-	ko:K03486	-	-	-	-	ko00000,ko03000	-	-	-	GntR,UTRA
k141_1424_29	926692.AZYG01000086_gene731	3.16e-297	823.0	COG0366@1|root,COG0366@2|Bacteria,1TP53@1239|Firmicutes,247XR@186801|Clostridia,3WAEN@53433|Halanaerobiales	186801|Clostridia	G	PFAM Alpha amylase, catalytic domain	treC	-	3.2.1.1,3.2.1.93	ko:K01176,ko:K01226	ko00500,ko01100,ko04973,map00500,map01100,map04973	-	R00837,R02108,R02112,R06113,R11262	RC00049	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,Malt_amylase_C
k141_1424_30	941824.TCEL_01370	5.55e-266	737.0	COG1263@1|root,COG1264@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,1TP5X@1239|Firmicutes,247WT@186801|Clostridia,36DI9@31979|Clostridiaceae	186801|Clostridia	G	Pts system	treP	-	2.7.1.201	ko:K02818,ko:K02819	ko00500,ko02060,map00500,map02060	M00270	R02780	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.1.2.13,4.A.1.2.4,4.A.1.2.8	-	-	PTS_EIIA_1,PTS_EIIB,PTS_EIIC
k141_1424_32	1345695.CLSA_c03410	3.3e-15	79.7	COG3863@1|root,COG3863@2|Bacteria,1VESN@1239|Firmicutes,24E63@186801|Clostridia,36HGS@31979|Clostridiaceae	186801|Clostridia	M	PFAM Orthopoxvirus protein of	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C92
k141_441_1	318464.IO99_15690	4.87e-41	136.0	2E3YG@1|root,32YVG@2|Bacteria,1VE9M@1239|Firmicutes,24MXS@186801|Clostridia,36KGR@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_441_2	1121451.DESAM_21351	1.68e-174	496.0	COG0697@1|root,COG0697@2|Bacteria,1MZX4@1224|Proteobacteria,42V2N@68525|delta/epsilon subdivisions,2WRIH@28221|Deltaproteobacteria,2M9QA@213115|Desulfovibrionales	28221|Deltaproteobacteria	EG	spore germination	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_3505_2	717774.Marme_0803	5.5e-44	156.0	COG0624@1|root,COG0624@2|Bacteria,1MUSU@1224|Proteobacteria,1RNIW@1236|Gammaproteobacteria,1XJUY@135619|Oceanospirillales	135619|Oceanospirillales	E	peptidase M20	-	-	3.4.17.11	ko:K01295	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
k141_3505_3	1238450.VIBNISOn1_910019	0.0	885.0	COG2759@1|root,COG2759@2|Bacteria,1MUR8@1224|Proteobacteria,1RME6@1236|Gammaproteobacteria,1XUVS@135623|Vibrionales	135623|Vibrionales	F	Belongs to the formate--tetrahydrofolate ligase family	fhs	GO:0000096,GO:0000097,GO:0000105,GO:0003674,GO:0003824,GO:0004329,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006144,GO:0006520,GO:0006547,GO:0006555,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006766,GO:0006767,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009108,GO:0009110,GO:0009112,GO:0009113,GO:0009256,GO:0009257,GO:0009396,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0016874,GO:0016879,GO:0018130,GO:0019238,GO:0019438,GO:0019752,GO:0032787,GO:0034641,GO:0042364,GO:0042398,GO:0042440,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046112,GO:0046148,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0052803,GO:0055086,GO:0055114,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	6.3.4.3	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R00943	RC00026,RC00111	ko00000,ko00001,ko00002,ko01000	-	-	-	FTHFS
k141_3505_4	338963.Pcar_3046	1.52e-158	446.0	COG2519@1|root,COG2519@2|Bacteria,1MXAK@1224|Proteobacteria,42NCI@68525|delta/epsilon subdivisions,2WJUH@28221|Deltaproteobacteria,43UBG@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Mycolic acid cyclopropane synthetase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
k141_1770_1	1248232.BANQ01000016_gene715	1.51e-170	483.0	COG0451@1|root,COG0451@2|Bacteria,1MUGT@1224|Proteobacteria,1RMPQ@1236|Gammaproteobacteria,1XUPH@135623|Vibrionales	135623|Vibrionales	GM	Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction	fcl	-	1.1.1.271	ko:K02377	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R05692	RC01014	ko00000,ko00001,ko01000	-	-	-	Epimerase
k141_1770_2	1248232.BANQ01000016_gene714	1.35e-227	632.0	COG1089@1|root,COG1089@2|Bacteria,1MUX0@1224|Proteobacteria,1RMIY@1236|Gammaproteobacteria,1XWBR@135623|Vibrionales	135623|Vibrionales	M	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose	gmd	GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008446,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009987,GO:0016051,GO:0016829,GO:0016835,GO:0016836,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509	4.2.1.47	ko:K01711	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R00888	RC00402	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
k141_1770_3	1123326.JFBL01000004_gene2116	9.37e-120	355.0	COG0438@1|root,COG0438@2|Bacteria,1N0DG@1224|Proteobacteria,42MJF@68525|delta/epsilon subdivisions,2YMG5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	hmm pf00534	pglA	GO:0003674,GO:0003824,GO:0006464,GO:0006486,GO:0006487,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0018193,GO:0018196,GO:0018279,GO:0019538,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0070085,GO:0071704,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	2.4.1.290	ko:K15914	-	-	R10188	RC00005,RC00049	ko00000,ko01000,ko01003	-	GT4	-	Glyco_trans_4_2,Glycos_transf_1
k141_1058_2	179408.Osc7112_5184	2.01e-279	838.0	COG1020@1|root,COG1020@2|Bacteria,1G0XE@1117|Cyanobacteria,1H7F4@1150|Oscillatoriales	1117|Cyanobacteria	Q	Amino acid adenylation domain protein	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,NAD_binding_4,PP-binding,TPR_1,TPR_8,Thioesterase
k141_3123_2	55601.VANGNB10_cI2171c	1.03e-207	587.0	COG0771@1|root,COG0771@2|Bacteria,1MVYD@1224|Proteobacteria,1RP25@1236|Gammaproteobacteria,1XUNN@135623|Vibrionales	135623|Vibrionales	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008764,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_C,Mur_ligase_M
k141_3123_3	1219065.VPR01S_21_00850	5.15e-216	604.0	COG0772@1|root,COG0772@2|Bacteria,1MVDB@1224|Proteobacteria,1RMIV@1236|Gammaproteobacteria,1XUU9@135623|Vibrionales	135623|Vibrionales	D	Peptidoglycan polymerase that is essential for cell division	ftsW	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
k141_3123_4	1280001.BAOA01000021_gene914	4.29e-184	520.0	COG0707@1|root,COG0707@2|Bacteria,1MVIB@1224|Proteobacteria,1RMQ3@1236|Gammaproteobacteria,1XSDU@135623|Vibrionales	135623|Vibrionales	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
k141_2092_1	223926.28805665	3.09e-41	147.0	COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,1MUWT@1224|Proteobacteria,1RN2M@1236|Gammaproteobacteria,1XST0@135623|Vibrionales	135623|Vibrionales	H	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate	ribD	-	1.1.1.193,3.5.4.26	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C,dCMP_cyt_deam_1
k141_2092_6	243277.VC_2266	1.66e-158	453.0	COG0611@1|root,COG0611@2|Bacteria,1MU9X@1224|Proteobacteria,1RNHU@1236|Gammaproteobacteria,1XTKW@135623|Vibrionales	135623|Vibrionales	F	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1	thiL	-	2.7.4.16	ko:K00946	ko00730,ko01100,map00730,map01100	M00127	R00617	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
k141_2092_7	1187848.AJYQ01000069_gene2679	4.53e-85	254.0	COG1267@1|root,COG1267@2|Bacteria,1MZJA@1224|Proteobacteria,1S68A@1236|Gammaproteobacteria,1XTFB@135623|Vibrionales	135623|Vibrionales	I	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)	pgpA	-	3.1.3.27	ko:K01095	ko00564,ko01100,map00564,map01100	-	R02029	RC00017	ko00000,ko00001,ko01000	-	-	-	PgpA
k141_2092_8	1280001.BAOA01000081_gene2976	4.65e-46	152.0	28NXJ@1|root,2ZBV4@2|Bacteria,1RD2V@1224|Proteobacteria,1S3XU@1236|Gammaproteobacteria,1XXER@135623|Vibrionales	135623|Vibrionales	S	Belongs to the UPF0325 family	-	-	-	-	-	-	-	-	-	-	-	-	DUF3461
k141_1771_1	196367.JNFG01000007_gene6900	2.2e-19	89.0	COG3279@1|root,COG3279@2|Bacteria,1MUE8@1224|Proteobacteria,2WEFP@28216|Betaproteobacteria,1KAB7@119060|Burkholderiaceae	28216|Betaproteobacteria	KT	LytTr DNA-binding domain	algR	-	-	ko:K08083	ko02020,map02020	M00493	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	LytTR,Response_reg
k141_443_1	1441629.PCH70_31300	3.44e-13	72.0	2AXBE@1|root,32SE7@2|Bacteria,1N2SV@1224|Proteobacteria,1SBH2@1236|Gammaproteobacteria,1Z8EC@136849|Pseudomonas syringae group	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_3506_1	933262.AXAM01000009_gene1475	3.38e-70	228.0	COG0628@1|root,COG0628@2|Bacteria,1MVX7@1224|Proteobacteria,42P90@68525|delta/epsilon subdivisions,2WK8R@28221|Deltaproteobacteria,2MI3H@213118|Desulfobacterales	28221|Deltaproteobacteria	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
k141_130_1	796620.VIBC2010_18709	2.88e-119	358.0	28HIF@1|root,2Z7TX@2|Bacteria,1MY24@1224|Proteobacteria,1RN69@1236|Gammaproteobacteria,1XWMY@135623|Vibrionales	135623|Vibrionales	S	Bacteriophage replication gene A protein (GPA)	-	-	-	-	-	-	-	-	-	-	-	-	Phage_GPA
k141_130_4	796620.VIBC2010_18694	6.67e-49	162.0	2EIXR@1|root,33CNZ@2|Bacteria,1NQB5@1224|Proteobacteria,1SJ80@1236|Gammaproteobacteria,1XZ9P@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_130_5	796620.VIBC2010_18679	5.16e-140	397.0	COG0433@1|root,COG0433@2|Bacteria,1N9XI@1224|Proteobacteria,1SCPX@1236|Gammaproteobacteria,1XVVG@135623|Vibrionales	135623|Vibrionales	S	COG0433 Predicted ATPase	VP1577	-	-	-	-	-	-	-	-	-	-	-	-
k141_130_7	1051646.VITU9109_18940	1.64e-137	395.0	2CEFX@1|root,34B3J@2|Bacteria,1P0R4@1224|Proteobacteria,1SSPS@1236|Gammaproteobacteria,1XTMJ@135623|Vibrionales	135623|Vibrionales	-	-	VPA0901	-	-	-	-	-	-	-	-	-	-	-	-
k141_130_8	796620.VIBC2010_18664	4.13e-19	81.3	29RHC@1|root,30CKA@2|Bacteria,1QMPQ@1224|Proteobacteria,1TJZD@1236|Gammaproteobacteria,1Y1VZ@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_130_9	796620.VIBC2010_18659	1.34e-15	69.7	29S7F@1|root,30DBX@2|Bacteria,1QMR5@1224|Proteobacteria,1TK0V@1236|Gammaproteobacteria,1Y1XR@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_130_10	796620.VIBC2010_18654	6.03e-13	64.3	2AXVX@1|root,31PX6@2|Bacteria,1QMJX@1224|Proteobacteria,1TJVF@1236|Gammaproteobacteria,1Y1R2@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_130_11	796620.VIBC2010_18649	2.31e-17	80.5	2B34X@1|root,31VSN@2|Bacteria,1QTNP@1224|Proteobacteria,1TIP5@1236|Gammaproteobacteria,1XZEH@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_130_12	1051646.VITU9109_18965	3.53e-06	52.4	2B4NJ@1|root,31XEU@2|Bacteria,1QK49@1224|Proteobacteria,1TI76@1236|Gammaproteobacteria,1XYJ4@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_130_15	1443665.JACA01000001_gene2556	2.11e-09	62.8	COG4675@1|root,COG4675@2|Bacteria	2|Bacteria	M	tail collar domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Collar,DUF859
k141_130_17	796620.VIBC2010_18619	2.32e-45	151.0	2DNV9@1|root,32ZB3@2|Bacteria,1MZGP@1224|Proteobacteria,1SE04@1236|Gammaproteobacteria,1XY7K@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_130_19	1191299.AJYX01000042_gene2399	1.1e-27	101.0	2AWUG@1|root,31PZZ@2|Bacteria,1QMNW@1224|Proteobacteria,1TJYI@1236|Gammaproteobacteria,1Y1UT@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_130_20	945550.VISI1226_20645	9.41e-21	82.8	2AWX8@1|root,31NUU@2|Bacteria,1QKIH@1224|Proteobacteria,1TINR@1236|Gammaproteobacteria,1XZDU@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_131_1	933262.AXAM01000001_gene328	9.12e-55	181.0	COG0682@1|root,COG0682@2|Bacteria,1MVE3@1224|Proteobacteria,42M2I@68525|delta/epsilon subdivisions,2WNPT@28221|Deltaproteobacteria,2MIZH@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
k141_3790_1	933262.AXAM01000078_gene1603	2.37e-126	388.0	COG0542@1|root,COG0542@2|Bacteria,1MURH@1224|Proteobacteria,42M9S@68525|delta/epsilon subdivisions,2WJSZ@28221|Deltaproteobacteria,2MHW3@213118|Desulfobacterales	28221|Deltaproteobacteria	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
k141_1059_1	563192.HMPREF0179_02375	1.98e-51	179.0	COG1166@1|root,COG1166@2|Bacteria,1MU80@1224|Proteobacteria,42M2B@68525|delta/epsilon subdivisions,2WJDZ@28221|Deltaproteobacteria,2M8IC@213115|Desulfovibrionales	28221|Deltaproteobacteria	H	arginine decarboxylase	speA	-	4.1.1.19	ko:K01585	ko00330,ko01100,map00330,map01100	M00133	R00566	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N
k141_1059_2	1167006.UWK_01846	5.6e-86	265.0	COG1108@1|root,COG1108@2|Bacteria,1MVC2@1224|Proteobacteria,42MYM@68525|delta/epsilon subdivisions,2WJAM@28221|Deltaproteobacteria,2MIQY@213118|Desulfobacterales	28221|Deltaproteobacteria	P	PFAM ABC 3 transport family	-	-	-	ko:K09816,ko:K09819	ko02010,map02010	M00242,M00243	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15,3.A.1.15.3,3.A.1.15.5	-	-	ABC-3
k141_1059_3	177437.HRM2_12140	8.14e-80	248.0	COG1121@1|root,COG1121@2|Bacteria,1MUDW@1224|Proteobacteria,42NI8@68525|delta/epsilon subdivisions,2WKMZ@28221|Deltaproteobacteria,2MHMM@213118|Desulfobacterales	28221|Deltaproteobacteria	P	PFAM ABC transporter	-	-	-	ko:K09817	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ABC_tran
k141_1426_2	1265505.ATUG01000003_gene216	2.39e-80	247.0	COG1136@1|root,COG1136@2|Bacteria,1MVSQ@1224|Proteobacteria,42QNS@68525|delta/epsilon subdivisions,2WMSN@28221|Deltaproteobacteria,2MIR6@213118|Desulfobacterales	28221|Deltaproteobacteria	V	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner	lolD	-	-	ko:K09810	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.125	-	-	ABC_tran
k141_1426_3	1232437.KL662013_gene1361	4.95e-121	362.0	COG4591@1|root,COG4591@2|Bacteria,1MVV7@1224|Proteobacteria,42MV0@68525|delta/epsilon subdivisions,2WITK@28221|Deltaproteobacteria,2MHM1@213118|Desulfobacterales	28221|Deltaproteobacteria	M	TIGRFAM lipoprotein releasing system, transmembrane protein, LolC E family	lolC	-	-	ko:K09808	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125	-	-	FtsX,MacB_PCD
k141_1772_3	1237149.C900_01218	1.34e-68	218.0	COG3335@1|root,COG3415@1|root,COG3335@2|Bacteria,COG3415@2|Bacteria,4NM4S@976|Bacteroidetes,47PK6@768503|Cytophagia	976|Bacteroidetes	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3
k141_3508_1	330214.NIDE1482	2.56e-53	189.0	COG0741@1|root,COG0741@2|Bacteria	2|Bacteria	M	lytic transglycosylase activity	mltC	GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008932,GO:0008933,GO:0009056,GO:0009057,GO:0009253,GO:0009279,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0019867,GO:0030203,GO:0030288,GO:0030312,GO:0030313,GO:0031224,GO:0031225,GO:0031975,GO:0033554,GO:0034599,GO:0042221,GO:0042597,GO:0043170,GO:0044425,GO:0044462,GO:0044464,GO:0046677,GO:0050896,GO:0051716,GO:0061783,GO:0070887,GO:0071236,GO:0071704,GO:0071944,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575	-	ko:K08306,ko:K08308,ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	iAF1260.b1193,iB21_1397.B21_01178,iBWG_1329.BWG_1018,iECBD_1354.ECBD_2429,iECB_1328.ECB_01168,iECDH10B_1368.ECDH10B_1246,iECDH1ME8569_1439.ECDH1ME8569_1132,iECD_1391.ECD_01168,iEcDH1_1363.EcDH1_2455,iEcolC_1368.EcolC_2432,iG2583_1286.G2583_3622,iJO1366.b1193,iUMNK88_1353.UMNK88_1507,iUMNK88_1353.UMNK88_3661,iY75_1357.Y75_RS06225	DUF3393,SLT
k141_3508_2	1208321.D104_07700	2.34e-40	153.0	COG0457@1|root,COG3014@1|root,COG0457@2|Bacteria,COG3014@2|Bacteria,1PD4S@1224|Proteobacteria,1RQ8Y@1236|Gammaproteobacteria,1XJIR@135619|Oceanospirillales	135619|Oceanospirillales	S	protein conserved in bacteria	-	-	-	ko:K09859	-	-	-	-	ko00000	-	-	-	-
k141_1773_1	1196835.A458_00275	1.04e-128	373.0	COG0384@1|root,COG0384@2|Bacteria,1MUAS@1224|Proteobacteria,1S32C@1236|Gammaproteobacteria,1Z43V@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	S	Phenazine biosynthesis-like protein	-	-	-	ko:K07054	-	-	-	-	ko00000	-	-	-	PhzC-PhzF
k141_1061_1	999141.GME_15515	1.69e-07	52.0	COG4239@1|root,COG4239@2|Bacteria,1MUM5@1224|Proteobacteria,1RNUH@1236|Gammaproteobacteria,1XHM2@135619|Oceanospirillales	135619|Oceanospirillales	P	ABC transporter permease	oppC	-	-	ko:K13895	ko02010,map02010	M00349	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.21,3.A.1.5.24	-	-	BPD_transp_1,OppC_N
k141_1061_2	981369.JQMJ01000004_gene6016	2.55e-48	174.0	COG1123@1|root,COG4172@2|Bacteria,2H3HY@201174|Actinobacteria,2NHEX@228398|Streptacidiphilus	201174|Actinobacteria	P	Oligopeptide/dipeptide transporter, C-terminal region	oppD	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	ko:K02031,ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
k141_3791_1	96561.Dole_0344	1.28e-195	567.0	COG0370@1|root,COG0370@2|Bacteria,1MUZC@1224|Proteobacteria,42MCY@68525|delta/epsilon subdivisions,2WIWJ@28221|Deltaproteobacteria,2MIW3@213118|Desulfobacterales	28221|Deltaproteobacteria	P	transporter of a GTP-driven Fe(2 ) uptake system	feoB-2	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoB_C,FeoB_N,Gate
k141_3791_2	1304885.AUEY01000004_gene968	4.81e-57	181.0	COG3807@1|root,COG3807@2|Bacteria,1RIYJ@1224|Proteobacteria,42SNK@68525|delta/epsilon subdivisions,2WPNS@28221|Deltaproteobacteria,2MK8E@213118|Desulfobacterales	28221|Deltaproteobacteria	S	SH3 domain	-	-	-	-	-	-	-	-	-	-	-	-	SH3_4
k141_1063_1	713587.THITH_06510	5.56e-92	277.0	COG0463@1|root,COG0463@2|Bacteria,1PGQU@1224|Proteobacteria,1RXHR@1236|Gammaproteobacteria,1X1QY@135613|Chromatiales	135613|Chromatiales	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
k141_2093_1	1219077.VAZ01S_072_00160	3.97e-56	178.0	COG0319@1|root,COG0319@2|Bacteria,1MZ67@1224|Proteobacteria,1S6BS@1236|Gammaproteobacteria,1XWWW@135623|Vibrionales	135623|Vibrionales	J	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA	ybeY	-	-	ko:K07042	-	-	-	-	ko00000,ko03009	-	-	-	UPF0054
k141_4484_2	1124991.MU9_2339	5.8e-70	218.0	COG3863@1|root,COG3863@2|Bacteria,1RBGX@1224|Proteobacteria,1S01D@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family	yiiX	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C92
k141_462_1	1304885.AUEY01000024_gene2713	0.0	952.0	COG1256@1|root,COG1256@2|Bacteria,1MV2M@1224|Proteobacteria,42PBN@68525|delta/epsilon subdivisions,2WMU3@28221|Deltaproteobacteria,2MIDK@213118|Desulfobacterales	28221|Deltaproteobacteria	N	TIGRFAM flagellar hook-associated protein FlgK	flgK	-	-	ko:K02396	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod,Flg_bbr_C
k141_462_2	1304885.AUEY01000024_gene2712	9.18e-199	597.0	COG1344@1|root,COG1344@2|Bacteria,1N1QF@1224|Proteobacteria,42TTV@68525|delta/epsilon subdivisions,2WRHH@28221|Deltaproteobacteria,2MIYN@213118|Desulfobacterales	28221|Deltaproteobacteria	N	Bacterial flagellin N-terminal helical region	-	-	-	ko:K02397	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flagellin_C,Flagellin_N
k141_2422_1	1188252.AJYK01000017_gene1615	2.37e-34	124.0	COG4215@1|root,COG4215@2|Bacteria,1MY2N@1224|Proteobacteria,1RNYD@1236|Gammaproteobacteria,1XT6H@135623|Vibrionales	135623|Vibrionales	P	COG4215 ABC-type arginine transport system, permease component	aotQ	-	-	ko:K10024	ko02010,map02010	M00235	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3.11	-	-	BPD_transp_1
k141_2422_2	55601.VANGNB10_cI1687c	3.61e-127	365.0	COG4160@1|root,COG4160@2|Bacteria,1MWI6@1224|Proteobacteria,1RPT1@1236|Gammaproteobacteria,1XT23@135623|Vibrionales	135623|Vibrionales	P	COG4160 ABC-type arginine histidine transport system, permease component	aotM	-	-	ko:K10023	ko02010,map02010	M00235	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3.11	-	-	BPD_transp_1
k141_2422_3	945543.VIBR0546_21000	1.29e-169	476.0	COG0708@1|root,COG0708@2|Bacteria,1MVII@1224|Proteobacteria,1RN4H@1236|Gammaproteobacteria,1XVBK@135623|Vibrionales	135623|Vibrionales	L	COG0708 Exonuclease III	xthA	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
k141_154_1	574375.BAGA_28765	2.25e-73	235.0	COG0535@1|root,COG0535@2|Bacteria,1TR52@1239|Firmicutes,4HAY2@91061|Bacilli,1ZBK3@1386|Bacillus	91061|Bacilli	C	Fe-S oxidoreductases	-	-	-	ko:K22227	-	-	-	-	ko00000	-	-	-	Fer4_12,Fer4_14,Radical_SAM,SPASM
k141_154_3	675814.VIC_000546	7.16e-105	308.0	COG0775@1|root,COG0775@2|Bacteria,1MY5S@1224|Proteobacteria,1RNSF@1236|Gammaproteobacteria,1XTZ2@135623|Vibrionales	135623|Vibrionales	F	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively	mtnN	GO:0003674,GO:0003824,GO:0008477,GO:0008782,GO:0008930,GO:0016787,GO:0016798,GO:0016799	3.2.2.9	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	M00034,M00609	R00194,R01401	RC00063,RC00318	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
k141_155_1	796620.VIBC2010_15279	8.1e-24	103.0	2AVXK@1|root,31MRN@2|Bacteria,1QJID@1224|Proteobacteria,1THIM@1236|Gammaproteobacteria,1XW51@135623|Vibrionales	135623|Vibrionales	S	N-acyl homoserine lactone synthase activity	luxM	-	2.3.1.184	ko:K13062	ko00270,ko01100,ko02024,map00270,map01100,map02024	-	R08940	RC00021,RC00039	ko00000,ko00001,ko01000	-	-	-	AHL_synthase
k141_464_2	1121033.AUCF01000039_gene442	5.65e-05	46.2	COG1416@1|root,COG1416@2|Bacteria,1PTM0@1224|Proteobacteria,2UZJB@28211|Alphaproteobacteria,2JY7Y@204441|Rhodospirillales	204441|Rhodospirillales	S	DsrE/DsrF-like family	-	-	-	-	-	-	-	-	-	-	-	-	DrsE
k141_2423_1	1123073.KB899241_gene2253	1.03e-16	82.8	COG0132@1|root,COG0132@2|Bacteria,1RDRK@1224|Proteobacteria,1RSHS@1236|Gammaproteobacteria,1X3VC@135614|Xanthomonadales	135614|Xanthomonadales	H	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring	bioD	GO:0003674,GO:0003824,GO:0004141,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0017144,GO:0018130,GO:0019752,GO:0032787,GO:0034641,GO:0042364,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.3.3	ko:K01935	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03182	RC00868	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_26
k141_2423_2	941449.dsx2_0784	1.31e-14	75.1	COG0502@1|root,COG0502@2|Bacteria,1MVFF@1224|Proteobacteria,42NGR@68525|delta/epsilon subdivisions,2WIMA@28221|Deltaproteobacteria,2M83D@213115|Desulfovibrionales	28221|Deltaproteobacteria	H	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism	bioB	-	2.8.1.6,5.4.99.58	ko:K01012,ko:K16180	ko00300,ko00780,ko01100,ko01120,map00300,map00780,map01100,map01120	M00123,M00573,M00577	R01078,R10010	RC00441,RC02995	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1582	BATS,Radical_SAM
k141_4822_1	1121396.KB892935_gene3845	4.95e-47	151.0	COG0236@1|root,COG0236@2|Bacteria,1P23P@1224|Proteobacteria,4320N@68525|delta/epsilon subdivisions,2WWEE@28221|Deltaproteobacteria,2MNVC@213118|Desulfobacterales	28221|Deltaproteobacteria	IQ	Phosphopantetheine attachment site	-	-	-	-	-	-	-	-	-	-	-	-	PP-binding
k141_1790_1	673860.AciM339_0292	3.57e-62	226.0	COG4870@1|root,arCOG02501@1|root,arCOG03439@1|root,arCOG02501@2157|Archaea,arCOG03439@2157|Archaea,arCOG03614@2157|Archaea,2XZI4@28890|Euryarchaeota	28890|Euryarchaeota	O	Papain family cysteine protease	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C1
k141_3613_3	55601.VANGNB10_cI1087	3.49e-79	249.0	COG0297@1|root,COG0297@2|Bacteria,1MUGM@1224|Proteobacteria,1RNMP@1236|Gammaproteobacteria,1XSTA@135623|Vibrionales	135623|Vibrionales	F	Synthesizes alpha-1,4-glucan chains using ADP-glucose	glgA	GO:0000271,GO:0003674,GO:0003824,GO:0004373,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0008194,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0035251,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046527,GO:0055114,GO:0071704,GO:1901576	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Glyco_transf_5,Glycos_transf_1
k141_2246_4	1304885.AUEY01000005_gene843	3.16e-158	464.0	COG1007@1|root,COG1007@2|Bacteria,1MV56@1224|Proteobacteria,42P7Z@68525|delta/epsilon subdivisions,2WKS0@28221|Deltaproteobacteria,2MIJK@213118|Desulfobacterales	28221|Deltaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
k141_2246_5	1304885.AUEY01000005_gene842	3e-42	153.0	COG1008@1|root,COG1008@2|Bacteria,1MV7V@1224|Proteobacteria,42NGD@68525|delta/epsilon subdivisions,2WJDC@28221|Deltaproteobacteria,2MJG3@213118|Desulfobacterales	28221|Deltaproteobacteria	C	TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M	nuoM	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q5_N,Proton_antipo_M
k141_1543_1	331636.G5O_0771	9.04e-35	135.0	COG0166@1|root,COG0166@2|Bacteria,2JFI4@204428|Chlamydiae	204428|Chlamydiae	F	glucose-6-phosphate isomerase	pgi	-	5.3.1.9	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI
k141_808_2	177437.HRM2_29500	1.58e-39	143.0	COG2304@1|root,COG2304@2|Bacteria,1MXQ7@1224|Proteobacteria,42NWB@68525|delta/epsilon subdivisions,2WKKE@28221|Deltaproteobacteria,2MIJF@213118|Desulfobacterales	28221|Deltaproteobacteria	S	PFAM von Willebrand factor type A domain	batA	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	BatA,VWA
k141_2247_1	498211.CJA_2898	2.03e-12	67.8	COG0406@1|root,COG0406@2|Bacteria,1RHAT@1224|Proteobacteria,1S69R@1236|Gammaproteobacteria,1FHBK@10|Cellvibrio	1236|Gammaproteobacteria	G	Histidine phosphatase superfamily (branch 1)	cobC	-	3.1.3.73,5.4.2.12	ko:K02226,ko:K15634	ko00010,ko00260,ko00680,ko00860,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map00860,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00122	R01518,R04594,R11173	RC00017,RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	His_Phos_1
k141_2247_2	1136163.M565_ctg1P1171	2.07e-53	174.0	COG2087@1|root,COG2087@2|Bacteria,1RH0A@1224|Proteobacteria,1S42M@1236|Gammaproteobacteria,1XXMV@135623|Vibrionales	135623|Vibrionales	H	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate	cobU	-	2.7.1.156,2.7.7.62	ko:K02231	ko00860,ko01100,map00860,map01100	M00122	R05221,R05222,R06558	RC00002,RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	CobU
k141_1250_1	223926.28808274	8.13e-86	262.0	COG0351@1|root,COG0351@2|Bacteria,1MU9J@1224|Proteobacteria,1RNFP@1236|Gammaproteobacteria,1XSEN@135623|Vibrionales	135623|Vibrionales	H	Phosphomethylpyrimidine kinase	thiD	-	2.7.1.49,2.7.4.7	ko:K00941	ko00730,ko01100,map00730,map01100	M00127	R03471,R04509	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Phos_pyr_kin
k141_1250_2	1348635.BBJY01000004_gene2922	1.51e-106	313.0	COG0745@1|root,COG0745@2|Bacteria,1RA00@1224|Proteobacteria,1S23N@1236|Gammaproteobacteria,1XSB7@135623|Vibrionales	135623|Vibrionales	T	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
k141_1250_3	1280001.BAOA01000130_gene1234	1.77e-79	257.0	COG0642@1|root,COG0642@2|Bacteria,1R54C@1224|Proteobacteria,1RNTM@1236|Gammaproteobacteria,1XUQE@135623|Vibrionales	135623|Vibrionales	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HisKA
k141_1250_4	1219076.N646_1161	1.5e-78	241.0	COG0435@1|root,COG0435@2|Bacteria,1MV50@1224|Proteobacteria,1RMTI@1236|Gammaproteobacteria,1XSAM@135623|Vibrionales	135623|Vibrionales	O	Glutathione S-transferase	-	-	1.8.5.7	ko:K07393	-	-	-	-	ko00000,ko01000	-	-	-	GST_C_2,GST_N_2
k141_575_3	1499967.BAYZ01000093_gene4035	1.68e-57	193.0	28RXC@1|root,2ZE9F@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_2248_2	1121405.dsmv_2802	2.53e-150	431.0	COG0039@1|root,COG0039@2|Bacteria,1MV57@1224|Proteobacteria,42KZJ@68525|delta/epsilon subdivisions,2WJ4U@28221|Deltaproteobacteria,2MJ7T@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Catalyzes the reversible oxidation of malate to oxaloacetate	mdh	-	1.1.1.37	ko:K00024	ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740	R00342,R07136	RC00031	ko00000,ko00001,ko00002,ko01000	-	-	-	Ldh_1_C,Ldh_1_N
k141_2248_3	96561.Dole_2373	9.33e-22	96.7	COG3118@1|root,COG3118@2|Bacteria,1REV3@1224|Proteobacteria,42RG6@68525|delta/epsilon subdivisions,2WNPR@28221|Deltaproteobacteria,2MJV2@213118|Desulfobacterales	28221|Deltaproteobacteria	O	belongs to the thioredoxin family	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_1265_1	1515746.HR45_07200	1.85e-50	197.0	COG3419@1|root,COG3419@2|Bacteria,1NUAV@1224|Proteobacteria,1RPV3@1236|Gammaproteobacteria,2Q91B@267890|Shewanellaceae	1236|Gammaproteobacteria	NU	Neisseria PilC beta-propeller domain	comC	-	-	ko:K02674	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	Neisseria_PilC,VWA_2
k141_311_1	335543.Sfum_3160	1.13e-52	176.0	COG1924@1|root,COG1924@2|Bacteria,1R6HU@1224|Proteobacteria,42PM0@68525|delta/epsilon subdivisions,2WJRP@28221|Deltaproteobacteria,2MRFC@213462|Syntrophobacterales	28221|Deltaproteobacteria	I	BadF/BadG/BcrA/BcrD ATPase family	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG
k141_311_2	536232.CLM_4134	5.93e-108	328.0	COG1775@1|root,COG1775@2|Bacteria,1TPEF@1239|Firmicutes,24A11@186801|Clostridia,36FZP@31979|Clostridiaceae	186801|Clostridia	E	2-hydroxyglutaryl-CoA dehydratase, D-component	-	-	-	-	-	-	-	-	-	-	-	-	HGD-D,HTH_30
k141_5227_1	1137799.GZ78_26030	1.02e-42	142.0	2EFP1@1|root,339F4@2|Bacteria,1NFZ9@1224|Proteobacteria,1SFAG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF600
k141_5227_2	1336233.JAEH01000022_gene2136	1.08e-09	58.5	2DRFE@1|root,33BH6@2|Bacteria,1NMTE@1224|Proteobacteria,1SHU7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_5227_4	1123053.AUDG01000012_gene1623	7.32e-62	205.0	COG1864@1|root,COG1864@2|Bacteria	2|Bacteria	F	neuron death in response to oxidative stress	-	-	-	ko:K01173	ko04210,map04210	-	-	-	ko00000,ko00001,ko03029	-	-	-	Endonuclea_NS_2,Endonuclease_NS,Excalibur
k141_1945_1	331678.Cphamn1_2545	1.54e-146	416.0	COG3177@1|root,COG3177@2|Bacteria	2|Bacteria	D	Filamentation induced by cAMP protein fic	fic	-	-	-	-	-	-	-	-	-	-	-	Fic
k141_1945_2	1278307.KB907023_gene803	4.08e-134	382.0	COG3153@1|root,COG3153@2|Bacteria	2|Bacteria	S	transferase activity, transferring acyl groups	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Acetyltransf_1,Acetyltransf_9
k141_1945_3	1444711.CCJF01000004_gene2485	5.48e-33	119.0	COG2606@1|root,COG2606@2|Bacteria	2|Bacteria	S	Cys-tRNA(Pro) hydrolase activity	ybaK_1	-	3.4.15.5	ko:K01284	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	tRNA_edit
k141_3638_3	1121396.KB893057_gene2515	6.09e-16	79.3	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,2MI1N@213118|Desulfobacterales	28221|Deltaproteobacteria	T	sigma-54 factor interaction domain-containing protein	pilR	-	-	ko:K02667	ko02020,map02020	M00501	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	HTH_8,Response_reg,Sigma54_activat
k141_1266_1	1304885.AUEY01000034_gene1873	2.23e-141	410.0	COG4174@1|root,COG4174@2|Bacteria,1MVKE@1224|Proteobacteria,43BKS@68525|delta/epsilon subdivisions,2X6YW@28221|Deltaproteobacteria,2MIBW@213118|Desulfobacterales	28221|Deltaproteobacteria	P	PFAM Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K13894	ko02010,map02010	M00349	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.21,3.A.1.5.24	-	-	BPD_transp_1
k141_1266_2	393595.ABO_1217	7.58e-35	130.0	COG4239@1|root,COG4239@2|Bacteria,1MUM5@1224|Proteobacteria,1RNUH@1236|Gammaproteobacteria,1XHM2@135619|Oceanospirillales	135619|Oceanospirillales	P	ABC transporter permease	oppC	-	-	ko:K13895	ko02010,map02010	M00349	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.21,3.A.1.5.24	-	-	BPD_transp_1,OppC_N
k141_5228_1	1348635.BBJY01000015_gene683	1.78e-109	347.0	COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,1RRSJ@1236|Gammaproteobacteria,1Y0HR@135623|Vibrionales	135623|Vibrionales	T	Cache domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,dCache_1
k141_4262_1	298386.PBPRB1940	1.21e-122	367.0	COG0534@1|root,COG0534@2|Bacteria,1R4H5@1224|Proteobacteria,1RS0B@1236|Gammaproteobacteria,1XTRQ@135623|Vibrionales	135623|Vibrionales	V	Na driven multidrug efflux pump	vmrA	-	-	-	-	-	-	-	-	-	-	-	MatE
k141_4262_2	573.JG24_05145	2.17e-37	135.0	COG1309@1|root,COG1309@2|Bacteria,1RIMK@1224|Proteobacteria,1SANF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
k141_4262_3	1116375.VEJY3_19346	3.94e-08	53.5	2ARAY@1|root,31GKY@2|Bacteria,1QEAW@1224|Proteobacteria,1TAW2@1236|Gammaproteobacteria,1XZEK@135623|Vibrionales	135623|Vibrionales	S	EF hand	-	-	-	-	-	-	-	-	-	-	-	-	EF-hand_5
k141_4262_7	1051646.VITU9109_07493	2.8e-142	409.0	COG1376@1|root,COG1376@2|Bacteria,1MVYT@1224|Proteobacteria,1RMNC@1236|Gammaproteobacteria,1XT0M@135623|Vibrionales	135623|Vibrionales	M	protein conserved in bacteria	-	-	-	ko:K16291,ko:K19236	ko01503,map01503	-	-	-	ko00000,ko00001,ko01002,ko01011	-	-	-	LysM,YkuD
k141_4262_8	1348635.BBJY01000001_gene2557	8.39e-205	582.0	COG0415@1|root,COG0415@2|Bacteria,1MV9Y@1224|Proteobacteria,1RNGJ@1236|Gammaproteobacteria,1XUEN@135623|Vibrionales	135623|Vibrionales	H	Belongs to the DNA photolyase family	phrB	GO:0003674,GO:0003824,GO:0003904,GO:0003913,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016830,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360	4.1.99.3	ko:K01669	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_photolyase,FAD_binding_7
k141_4262_9	223926.28809874	1.75e-75	238.0	COG0789@1|root,COG0789@2|Bacteria,1R9SN@1224|Proteobacteria,1S967@1236|Gammaproteobacteria,1XUT1@135623|Vibrionales	135623|Vibrionales	K	Transcriptional regulator MerR family	-	-	-	ko:K22491	-	-	-	-	ko00000,ko03000	-	-	-	MerR_1
k141_4262_10	674977.VMC_09000	1.3e-153	439.0	COG1683@1|root,COG3272@1|root,COG1683@2|Bacteria,COG3272@2|Bacteria,1MXYZ@1224|Proteobacteria,1RNMF@1236|Gammaproteobacteria,1XUJK@135623|Vibrionales	135623|Vibrionales	S	Protein of unknown function (DUF1722)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1722,DUF523
k141_4262_11	55601.VANGNB10_cII0143c	2.39e-65	214.0	COG0457@1|root,COG0457@2|Bacteria,1NFT4@1224|Proteobacteria,1SPMW@1236|Gammaproteobacteria,1XSHX@135623|Vibrionales	135623|Vibrionales	S	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_313_2	1517681.HW45_03785	1.13e-14	72.8	COG2433@1|root,COG2433@2|Bacteria,1QYSX@1224|Proteobacteria,1RX8U@1236|Gammaproteobacteria,1Y2AV@135623|Vibrionales	135623|Vibrionales	S	Transposase IS66 family	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS66
k141_2264_2	243277.VC_1427	1.27e-153	437.0	COG1176@1|root,COG1176@2|Bacteria,1MVGM@1224|Proteobacteria,1RNNZ@1236|Gammaproteobacteria,1XSQ9@135623|Vibrionales	135623|Vibrionales	P	Spermidine putrescine ABC transporter	potB	-	-	ko:K11071	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	BPD_transp_1
k141_2264_3	675816.VIA_003006	9.56e-193	543.0	COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,1RNPX@1236|Gammaproteobacteria,1XT3F@135623|Vibrionales	135623|Vibrionales	P	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system	potA	GO:0003674,GO:0003824,GO:0005215,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0015203,GO:0015399,GO:0015405,GO:0015417,GO:0015695,GO:0015696,GO:0015846,GO:0015847,GO:0015848,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0042623,GO:0042626,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:1902047	3.6.3.31	ko:K11072	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.11.1	-	-	ABC_tran,TOBE_2
k141_2264_4	672.VV93_v1c15740	1.44e-77	241.0	COG5473@1|root,COG5473@2|Bacteria,1N3T0@1224|Proteobacteria,1SEVY@1236|Gammaproteobacteria,1XTIE@135623|Vibrionales	135623|Vibrionales	-	-	VP1530	-	-	-	-	-	-	-	-	-	-	-	-
k141_3235_2	1348635.BBJY01000001_gene2425	1.12e-137	403.0	COG4148@1|root,COG4148@2|Bacteria,1MU8K@1224|Proteobacteria,1RQCV@1236|Gammaproteobacteria,1XZZP@135623|Vibrionales	135623|Vibrionales	P	TOBE domain	-	-	3.6.3.29	ko:K02017	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.8	-	-	ABC_tran,TOBE
k141_3235_4	870967.VIS19158_17326	6.6e-117	340.0	COG1720@1|root,COG1720@2|Bacteria,1MUF0@1224|Proteobacteria,1RPCX@1236|Gammaproteobacteria,1XU35@135623|Vibrionales	135623|Vibrionales	S	Uncharacterised protein family UPF0066	yaeB	-	-	-	-	-	-	-	-	-	-	-	UPF0066
k141_1267_1	1111728.ATYS01000008_gene1421	3.6e-15	74.3	COG0494@1|root,COG0494@2|Bacteria,1RCZM@1224|Proteobacteria,1S67W@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	belongs to the nudix hydrolase family	nudG	GO:0003674,GO:0003824,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360	3.6.1.55,3.6.1.65	ko:K03574,ko:K08320	-	-	-	-	ko00000,ko01000,ko03400	-	-	iE2348C_1286.E2348C_1887,iECP_1309.ECP_1705,iLF82_1304.LF82_1533,iNRG857_1313.NRG857_08815,iPC815.YPO2167,iSSON_1240.SSON_1397	NUDIX
k141_1267_2	998674.ATTE01000001_gene1024	3.05e-26	97.8	COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,1SCA7@1236|Gammaproteobacteria,46183@72273|Thiotrichales	72273|Thiotrichales	K	'Cold-shock' DNA-binding domain	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
k141_2841_2	1476973.JMMB01000007_gene316	5.3e-187	530.0	COG0281@1|root,COG0281@2|Bacteria,1TPJ3@1239|Firmicutes,2487U@186801|Clostridia,25QEB@186804|Peptostreptococcaceae	186801|Clostridia	C	Psort location Cytoplasmic, score	-	-	1.1.1.38	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	-	R00214	RC00105	ko00000,ko00001,ko01000	-	-	-	Malic_M,malic
k141_2841_3	1449126.JQKL01000006_gene800	5.11e-141	407.0	COG2070@1|root,COG2070@2|Bacteria,1TPC3@1239|Firmicutes,24831@186801|Clostridia,267MP@186813|unclassified Clostridiales	186801|Clostridia	S	Thiazole biosynthesis protein ThiG	-	-	1.13.12.16,1.3.1.9	ko:K00459,ko:K02371	ko00061,ko00910,ko01100,ko01212,map00061,map00910,map01100,map01212	M00083	R00025,R04429,R04724,R04955,R04958,R04961,R04966,R04969,R07765	RC00052,RC00076,RC02541,RC02759	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	NMO
k141_2841_4	457421.CBFG_03094	4.58e-61	202.0	COG0583@1|root,COG0583@2|Bacteria,1TQ6Y@1239|Firmicutes,25C6V@186801|Clostridia	186801|Clostridia	K	lysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
k141_2841_5	1230342.CTM_11223	5.97e-174	494.0	COG2502@1|root,COG2502@2|Bacteria,1TP28@1239|Firmicutes,248S4@186801|Clostridia,36DK2@31979|Clostridiaceae	186801|Clostridia	E	aspartate--ammonia ligase	asnA	-	6.3.1.1	ko:K01914	ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230	-	R00483	RC00010	ko00000,ko00001,ko01000	-	-	-	AsnA
k141_2841_7	1321778.HMPREF1982_02733	9.66e-81	258.0	28HHD@1|root,2Z7T3@2|Bacteria,1TRKJ@1239|Firmicutes,24A0Y@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF3810
k141_2841_9	887325.HMPREF0381_1327	1.03e-49	173.0	COG0169@1|root,COG0169@2|Bacteria,1TQRY@1239|Firmicutes,2497S@186801|Clostridia,1HUQW@1164882|Lachnoanaerobaculum	186801|Clostridia	E	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	aroE	-	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS14365	CM_2,SKI,Shikimate_DH,Shikimate_dh_N
k141_2841_12	1121324.CLIT_8c00290	3.67e-135	394.0	COG2876@1|root,COG2876@2|Bacteria,1TP61@1239|Firmicutes,24812@186801|Clostridia,25QJT@186804|Peptostreptococcaceae	186801|Clostridia	E	Psort location Cytoplasmic, score	aroF	-	2.5.1.54	ko:K03856	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS14395	DAHP_synth_1
k141_2841_13	1262449.CP6013_3396	6.41e-77	251.0	COG0077@1|root,COG0077@2|Bacteria,1TPDN@1239|Firmicutes,248G7@186801|Clostridia,36EMK@31979|Clostridiaceae	186801|Clostridia	E	chorismate mutase	pheA	-	4.2.1.51,5.4.99.5	ko:K04518,ko:K14170	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R00691,R01373,R01715	RC00360,RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,CM_2,PDT
k141_2841_14	1235792.C808_01375	8.04e-75	242.0	COG0337@1|root,COG0337@2|Bacteria,1TPKZ@1239|Firmicutes,248H4@186801|Clostridia,27IJR@186928|unclassified Lachnospiraceae	186801|Clostridia	E	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	-	4.2.3.4	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03083	RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase
k141_2841_15	545243.BAEV01000001_gene3151	3e-139	412.0	COG0128@1|root,COG0128@2|Bacteria,1TPIH@1239|Firmicutes,2488G@186801|Clostridia,36E1H@31979|Clostridiaceae	186801|Clostridia	E	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	aroA	-	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	EPSP_synthase
k141_2841_16	500633.CLOHIR_01485	3.07e-136	399.0	COG0082@1|root,COG0082@2|Bacteria,1TQ40@1239|Firmicutes,24998@186801|Clostridia,25QQR@186804|Peptostreptococcaceae	186801|Clostridia	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	-	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_synt
k141_2841_18	1348635.BBJY01000001_gene2669	3.95e-24	116.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,1XU0F@135623|Vibrionales	135623|Vibrionales	NT	Cache domain	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal,dCache_1
k141_2841_19	1347392.CCEZ01000012_gene2556	2.81e-179	509.0	COG0079@1|root,COG0079@2|Bacteria,1TPUV@1239|Firmicutes,24837@186801|Clostridia,36DDS@31979|Clostridiaceae	186801|Clostridia	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily	hisC	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
k141_2841_20	1280676.AUJO01000001_gene2240	0.000769	48.9	COG1266@1|root,COG1266@2|Bacteria,1V822@1239|Firmicutes,24CBM@186801|Clostridia,4BXIW@830|Butyrivibrio	186801|Clostridia	CP	CAAX protease self-immunity	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_3,Abi
k141_2841_22	1121289.JHVL01000056_gene2961	3.18e-44	155.0	2E6JA@1|root,3316D@2|Bacteria,1VK0E@1239|Firmicutes,24S2W@186801|Clostridia,36U3K@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_2841_24	1195246.AGRI_13975	8.21e-109	341.0	COG1874@1|root,COG1874@2|Bacteria,1R8CV@1224|Proteobacteria,1S0MI@1236|Gammaproteobacteria,469MV@72275|Alteromonadaceae	1236|Gammaproteobacteria	G	Glycosyl hydrolase family 14	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_14
k141_2841_25	1196322.A370_04719	6.09e-48	169.0	COG0384@1|root,COG0384@2|Bacteria,1TRAF@1239|Firmicutes,25D2F@186801|Clostridia,36DVZ@31979|Clostridiaceae	186801|Clostridia	S	Phenazine biosynthesis protein, PhzF family	-	-	5.3.3.17	ko:K06998	ko00405,ko01130,ko02024,map00405,map01130,map02024	M00835	-	-	ko00000,ko00001,ko00002,ko01000	-	-	-	PhzC-PhzF
k141_2841_26	386415.NT01CX_2428	1.95e-156	456.0	COG1114@1|root,COG1114@2|Bacteria,1TQIS@1239|Firmicutes,248I0@186801|Clostridia,36DC1@31979|Clostridiaceae	186801|Clostridia	E	Component of the transport system for branched-chain amino acids	-	-	-	ko:K03311	-	-	-	-	ko00000	2.A.26	-	-	Branch_AA_trans
k141_2841_27	1321778.HMPREF1982_04511	3.8e-103	304.0	COG0745@1|root,COG0745@2|Bacteria,1TR32@1239|Firmicutes,249TG@186801|Clostridia,2690P@186813|unclassified Clostridiales	186801|Clostridia	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
k141_2841_28	1415774.U728_3563	2.09e-43	160.0	COG0642@1|root,COG2205@2|Bacteria,1TSIC@1239|Firmicutes,248W8@186801|Clostridia,36VTI@31979|Clostridiaceae	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	2.7.13.3	ko:K11629	ko02020,map02020	M00469,M00738	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c
k141_2841_29	1321778.HMPREF1982_01633	7.21e-116	339.0	COG1136@1|root,COG1136@2|Bacteria,1TNZG@1239|Firmicutes,247JX@186801|Clostridia,267ME@186813|unclassified Clostridiales	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	-	-	-	ko:K02003,ko:K11635	ko02020,map02020	M00258,M00315	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.134.6	-	-	ABC_tran
k141_2841_30	1121289.JHVL01000012_gene1695	3.18e-104	337.0	COG0577@1|root,COG0577@2|Bacteria,1TR2D@1239|Firmicutes,2481J@186801|Clostridia,36EQ4@31979|Clostridiaceae	186801|Clostridia	V	ABC transporter permease	-	-	-	ko:K02004,ko:K11632	ko02010,ko02020,map02010,map02020	M00258,M00314,M00737,M00738	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.134.3	-	-	FtsX
k141_2841_31	1301100.HG529270_gene557	9.41e-50	178.0	COG0526@1|root,COG0526@2|Bacteria,1UY9A@1239|Firmicutes,24C03@186801|Clostridia,36KUB@31979|Clostridiaceae	186801|Clostridia	CO	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
k141_2841_33	1121324.CLIT_11c00110	6.09e-142	412.0	COG0252@1|root,COG0252@2|Bacteria,1TPP9@1239|Firmicutes,248F3@186801|Clostridia,25RQQ@186804|Peptostreptococcaceae	186801|Clostridia	EJ	Asparaginase	ansA	-	3.5.1.1	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	-	R00485	RC00010,RC02798	ko00000,ko00001,ko01000	-	-	-	Asparaginase
k141_2841_35	457396.CSBG_00859	4.29e-81	260.0	COG0477@1|root,COG0477@2|Bacteria,1V5JX@1239|Firmicutes,25FX2@186801|Clostridia,36U62@31979|Clostridiaceae	186801|Clostridia	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
k141_2841_41	1321778.HMPREF1982_01131	1.22e-113	335.0	COG0561@1|root,COG0561@2|Bacteria,1TR16@1239|Firmicutes,248MW@186801|Clostridia,26CPG@186813|unclassified Clostridiales	186801|Clostridia	S	Sucrose-6F-phosphate phosphohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
k141_2841_42	1304284.L21TH_1659	5.04e-40	138.0	2CIJU@1|root,332RU@2|Bacteria,1VESI@1239|Firmicutes,24QR7@186801|Clostridia,36MZM@31979|Clostridiaceae	186801|Clostridia	S	Domain of unknown function (DUF1893)	-	-	-	-	-	-	-	-	-	-	-	-	TM1506
k141_39_1	1202962.KB907158_gene3692	4.07e-26	103.0	COG1267@1|root,COG1267@2|Bacteria,1MZJA@1224|Proteobacteria,1S68A@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)	pgpA	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008962,GO:0009058,GO:0009987,GO:0010035,GO:0010038,GO:0016020,GO:0016021,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019637,GO:0030258,GO:0031224,GO:0031226,GO:0032026,GO:0042221,GO:0042577,GO:0042578,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044425,GO:0044459,GO:0044464,GO:0045017,GO:0046471,GO:0046474,GO:0046486,GO:0046839,GO:0050896,GO:0071704,GO:0071944,GO:0090407,GO:1901576	3.1.3.27	ko:K01095	ko00564,ko01100,map00564,map01100	-	R02029	RC00017	ko00000,ko00001,ko01000	-	-	iECSP_1301.ECSP_0485,iECUMN_1333.ECUMN_0456,iECs_1301.ECs0471,iG2583_1286.G2583_0529,iPC815.YPO3179,iZ_1308.Z0520	PgpA
k141_39_2	933262.AXAM01000028_gene3311	2.48e-124	371.0	COG2195@1|root,COG2195@2|Bacteria,1MV7D@1224|Proteobacteria,42MBD@68525|delta/epsilon subdivisions,2WJT1@28221|Deltaproteobacteria,2MI62@213118|Desulfobacterales	28221|Deltaproteobacteria	E	TIGRFAM peptidase T-like protein	-	-	3.4.11.4	ko:K01258	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
k141_39_3	443152.MDG893_02685	9.83e-18	92.8	COG0515@1|root,COG2199@1|root,COG3899@1|root,COG0515@2|Bacteria,COG3706@2|Bacteria,COG3899@2|Bacteria,1R7HC@1224|Proteobacteria,1T315@1236|Gammaproteobacteria,46AA9@72275|Alteromonadaceae	1236|Gammaproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GAF,GGDEF,Pkinase
k141_1386_1	1238450.VIBNISOn1_500001	1.7e-145	429.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria,1XTA5@135623|Vibrionales	135623|Vibrionales	T	COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
k141_360_1	933262.AXAM01000051_gene2977	2.03e-14	68.2	2EAFJ@1|root,334IY@2|Bacteria,1NA2Y@1224|Proteobacteria,42VJ1@68525|delta/epsilon subdivisions,2WRKE@28221|Deltaproteobacteria,2MKY4@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF1844)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1844
k141_4101_2	1280001.BAOA01000027_gene4791	4.85e-133	378.0	COG0118@1|root,COG0118@2|Bacteria,1MU4X@1224|Proteobacteria,1RRP3@1236|Gammaproteobacteria,1XUI3@135623|Vibrionales	135623|Vibrionales	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR	hisH	GO:0000105,GO:0000107,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	-	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
k141_4101_3	675815.VOA_000479	5.55e-229	634.0	COG0131@1|root,COG0241@1|root,COG0131@2|Bacteria,COG0241@2|Bacteria,1MWBS@1224|Proteobacteria,1RPA9@1236|Gammaproteobacteria,1XSE2@135623|Vibrionales	135623|Vibrionales	E	Histidine biosynthesis bifunctional protein HisB	hisB	GO:0000105,GO:0003674,GO:0003824,GO:0004401,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042578,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	3.1.3.15,4.2.1.19	ko:K01089	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03013,R03457	RC00017,RC00932	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPD,PNK3P
k141_4101_4	1280001.BAOA01000027_gene4793	2.53e-199	558.0	COG0079@1|root,COG0079@2|Bacteria,1MW7I@1224|Proteobacteria,1RP4T@1236|Gammaproteobacteria,1XTFK@135623|Vibrionales	135623|Vibrionales	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily	hisC	GO:0000105,GO:0003674,GO:0003824,GO:0004400,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
k141_4101_5	55601.VANGNB10_cI1068	1.16e-98	298.0	COG0141@1|root,COG0141@2|Bacteria,1MUUF@1224|Proteobacteria,1RMZD@1236|Gammaproteobacteria,1XTSW@135623|Vibrionales	135623|Vibrionales	E	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine	hisD	GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.23	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01158,R01163,R03012	RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000	-	-	-	Histidinol_dh
k141_707_2	1265505.ATUG01000002_gene1190	3.45e-64	215.0	COG0507@1|root,COG0507@2|Bacteria,1MW43@1224|Proteobacteria,42M8J@68525|delta/epsilon subdivisions,2WJD6@28221|Deltaproteobacteria,2MINC@213118|Desulfobacterales	28221|Deltaproteobacteria	L	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity	-	-	3.1.11.5	ko:K03581	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AAA_30,HHH_4,HHH_5,UvrD_C_2
k141_2735_1	644966.Tmar_1884	7.41e-22	96.7	COG1208@1|root,COG1208@2|Bacteria,1VDBC@1239|Firmicutes,24AGU@186801|Clostridia,3WDDZ@538999|Clostridiales incertae sedis	186801|Clostridia	M	MobA-like NTP transferase domain	-	-	2.7.7.13	ko:K00966	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	M00114,M00361,M00362	R00885	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
k141_2735_2	349521.HCH_06182	1.12e-79	243.0	COG0279@1|root,COG0279@2|Bacteria,1NVIE@1224|Proteobacteria,1RP6M@1236|Gammaproteobacteria,1XKC8@135619|Oceanospirillales	135619|Oceanospirillales	G	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate	-	-	5.3.1.28	ko:K03271	ko00540,ko01100,map00540,map01100	M00064	R05645,R09768,R09769	RC00434	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	SIS_2
k141_2735_3	1415779.JOMH01000001_gene2594	4.15e-135	395.0	COG2605@1|root,COG2605@2|Bacteria	2|Bacteria	G	GHMP kinase	hddA	-	2.7.1.168	ko:K07031	ko00540,map00540	-	R09770	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
k141_2735_4	28229.ND2E_1902	6.35e-45	157.0	COG0438@1|root,COG0438@2|Bacteria,1MU9C@1224|Proteobacteria,1RS5D@1236|Gammaproteobacteria,2Q6YQ@267889|Colwelliaceae	1236|Gammaproteobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
k141_2735_5	1089553.Tph_c15510	3.67e-17	85.1	COG0438@1|root,COG0438@2|Bacteria,1TPY6@1239|Firmicutes,24834@186801|Clostridia,42FGD@68295|Thermoanaerobacterales	186801|Clostridia	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
k141_3759_4	55601.VANGNB10_cI1960c	4.74e-163	461.0	COG0329@1|root,COG0329@2|Bacteria,1MUCM@1224|Proteobacteria,1RNH9@1236|Gammaproteobacteria,1XUPA@135623|Vibrionales	135623|Vibrionales	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA	GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008840,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
k141_3759_5	55601.VANGNB10_cI1959c	2.29e-97	298.0	COG3317@1|root,COG3317@2|Bacteria,1MUUK@1224|Proteobacteria,1RN2X@1236|Gammaproteobacteria,1XTAQ@135623|Vibrionales	135623|Vibrionales	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamC	-	-	ko:K07287	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	Lipoprotein_18
k141_3759_7	945550.VISI1226_02927	7.61e-88	266.0	COG1876@1|root,COG1876@2|Bacteria,1N2IC@1224|Proteobacteria,1S0DU@1236|Gammaproteobacteria,1XTV4@135623|Vibrionales	135623|Vibrionales	M	COG1876 D-alanyl-D-alanine carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	VanY
k141_3759_9	1116375.VEJY3_11670	6.34e-57	179.0	COG1393@1|root,COG1393@2|Bacteria,1MZ6S@1224|Proteobacteria,1S8TR@1236|Gammaproteobacteria,1XXZI@135623|Vibrionales	135623|Vibrionales	P	Belongs to the ArsC family	yffB	-	-	-	-	-	-	-	-	-	-	-	ArsC
k141_3759_11	223926.28810086	2.08e-141	412.0	COG3634@1|root,COG3634@2|Bacteria,1MUKD@1224|Proteobacteria,1RNC7@1236|Gammaproteobacteria,1XT7A@135623|Vibrionales	135623|Vibrionales	O	COG3634 Alkyl hydroperoxide reductase, large subunit	ahpF	-	-	ko:K03387	-	-	-	-	ko00000,ko01000	-	-	-	Pyr_redox_2,Thioredoxin_3
k141_2736_1	744872.Spica_0361	1.6e-120	367.0	COG1674@1|root,COG1674@2|Bacteria,2J63D@203691|Spirochaetes	203691|Spirochaetes	D	Belongs to the FtsK SpoIIIE SftA family	ftsK	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
k141_708_1	1123508.JH636441_gene3386	5.94e-26	123.0	COG2931@1|root,COG3210@1|root,COG4625@1|root,COG2931@2|Bacteria,COG3210@2|Bacteria,COG4625@2|Bacteria	2|Bacteria	T	pathogenesis	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,DUF4347,MAM,Trypsin_2
k141_4105_1	1212548.B381_08704	5.59e-06	48.1	COG2168@1|root,COG2168@2|Bacteria,1NGF3@1224|Proteobacteria,1SGPI@1236|Gammaproteobacteria,1Z3C3@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	P	conserved protein involved in oxidation of intracellular sulfur	tusB	GO:0002097,GO:0002098,GO:0002143,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1902494,GO:1990228,GO:1990234	-	ko:K07237	ko04122,map04122	-	-	-	ko00000,ko00001,ko03016	-	-	-	DsrH
k141_2737_1	1123274.KB899416_gene2633	1.7e-32	127.0	COG1541@1|root,COG1541@2|Bacteria,2J5UX@203691|Spirochaetes	203691|Spirochaetes	H	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)	-	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C_2
k141_3409_2	1187848.AJYQ01000006_gene674	2.72e-198	553.0	COG2358@1|root,COG2358@2|Bacteria,1MXW1@1224|Proteobacteria,1RQN1@1236|Gammaproteobacteria,1XU72@135623|Vibrionales	135623|Vibrionales	S	transport system periplasmic component	-	-	-	ko:K07080	-	-	-	-	ko00000	-	-	-	NMT1_3
k141_3409_3	675813.VIB_002104	5.02e-98	286.0	COG1438@1|root,COG1438@2|Bacteria,1N2AF@1224|Proteobacteria,1RSF7@1236|Gammaproteobacteria,1XSGI@135623|Vibrionales	135623|Vibrionales	K	Regulates arginine biosynthesis genes	argR	GO:0006082,GO:0006355,GO:0006520,GO:0006525,GO:0006807,GO:0008150,GO:0008152,GO:0009064,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0019752,GO:0031323,GO:0031326,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:1901564,GO:1901605,GO:1903506,GO:2000112,GO:2001141	-	ko:K03402	-	-	-	-	ko00000,ko03000	-	-	-	Arg_repressor,Arg_repressor_C
k141_3409_4	316275.VSAL_I0359	6.5e-175	493.0	COG0039@1|root,COG0039@2|Bacteria,1MV57@1224|Proteobacteria,1RMAX@1236|Gammaproteobacteria,1XSFW@135623|Vibrionales	135623|Vibrionales	C	Catalyzes the reversible oxidation of malate to oxaloacetate	mdh	GO:0003674,GO:0003824,GO:0004470,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016491,GO:0016614,GO:0016615,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350	1.1.1.37	ko:K00024	ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740	R00342,R07136	RC00031	ko00000,ko00001,ko00002,ko01000	-	-	-	Ldh_1_C,Ldh_1_N
k141_3409_5	575788.VS_0360	1.17e-190	534.0	COG0142@1|root,COG0142@2|Bacteria,1MUK6@1224|Proteobacteria,1RPR7@1236|Gammaproteobacteria,1XTYZ@135623|Vibrionales	135623|Vibrionales	H	Belongs to the FPP GGPP synthase family	ispB	-	2.5.1.90	ko:K02523	ko00900,ko01110,map00900,map01110	-	R09248	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	-	polyprenyl_synt
k141_3409_6	29495.EA26_02600	1.49e-67	204.0	COG0261@1|root,COG0261@2|Bacteria,1MZEW@1224|Proteobacteria,1S5VB@1236|Gammaproteobacteria,1XXAQ@135623|Vibrionales	135623|Vibrionales	J	This protein binds to 23S rRNA in the presence of protein L20	rplU	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02888	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L21p
k141_3409_7	1280001.BAOA01000021_gene819	3.63e-53	167.0	COG0211@1|root,COG0211@2|Bacteria,1MZGH@1224|Proteobacteria,1S8R2@1236|Gammaproteobacteria,1XXTX@135623|Vibrionales	135623|Vibrionales	J	Belongs to the bacterial ribosomal protein bL27 family	rpmA	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02899	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27
k141_3409_8	1219065.VPR01S_20_00630	4.77e-240	664.0	COG0536@1|root,COG0536@2|Bacteria,1MUGZ@1224|Proteobacteria,1RMFQ@1236|Gammaproteobacteria,1XSG0@135623|Vibrionales	135623|Vibrionales	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0005488,GO:0005525,GO:0017076,GO:0019001,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	GTP1_OBG,MMR_HSR1
k141_3409_9	243277.VC_0438	1.51e-137	395.0	COG2966@1|root,COG2966@2|Bacteria,1NH2X@1224|Proteobacteria,1RN1Q@1236|Gammaproteobacteria,1XSCP@135623|Vibrionales	135623|Vibrionales	S	Putative threonine/serine exporter	yjjP	-	-	-	-	-	-	-	-	-	-	-	ThrE
k141_3409_10	223926.28805315	1.75e-88	262.0	COG3610@1|root,COG3610@2|Bacteria,1RAWK@1224|Proteobacteria,1S2KX@1236|Gammaproteobacteria,1XX2R@135623|Vibrionales	135623|Vibrionales	S	Threonine/Serine exporter, ThrE	-	-	-	-	-	-	-	-	-	-	-	-	ThrE_2
k141_1388_1	1034347.CAHJ01000061_gene1047	2.29e-25	103.0	COG1670@1|root,COG1670@2|Bacteria,1V2C6@1239|Firmicutes,4HG3C@91061|Bacilli,1ZFP6@1386|Bacillus	91061|Bacilli	J	Acetyltransferase (GNAT) domain	yoaA	-	2.3.1.128	ko:K03790	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_3
k141_1388_2	1304885.AUEY01000004_gene938	8.07e-74	233.0	2EG7U@1|root,339ZP@2|Bacteria,1NV8R@1224|Proteobacteria,42ZI2@68525|delta/epsilon subdivisions,2WV0A@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_1388_3	941449.dsx2_0725	0.000677	42.0	COG2204@1|root,COG2204@2|Bacteria,1RKC4@1224|Proteobacteria,42SJ3@68525|delta/epsilon subdivisions,2WPI1@28221|Deltaproteobacteria,2MGHJ@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
k141_2738_1	1232437.KL661955_gene2370	5.71e-120	354.0	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,42MSR@68525|delta/epsilon subdivisions,2WIXG@28221|Deltaproteobacteria,2MIJC@213118|Desulfobacterales	28221|Deltaproteobacteria	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
k141_3762_2	439235.Dalk_1922	3.73e-56	177.0	COG0222@1|root,COG0222@2|Bacteria,1RGU4@1224|Proteobacteria,42SHZ@68525|delta/epsilon subdivisions,2WPFZ@28221|Deltaproteobacteria,2MK53@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation	rplL	-	-	ko:K02935	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L12,Ribosomal_L12_N
k141_3762_3	1121405.dsmv_3645	8.2e-125	392.0	COG0085@1|root,COG0085@2|Bacteria,1MUC4@1224|Proteobacteria,43DMZ@68525|delta/epsilon subdivisions,2WIW5@28221|Deltaproteobacteria,2MI5C@213118|Desulfobacterales	28221|Deltaproteobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
k141_40_1	1348635.BBJY01000010_gene1401	7.04e-112	331.0	COG2199@1|root,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,1RMA9@1236|Gammaproteobacteria,1XTUI@135623|Vibrionales	135623|Vibrionales	T	COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Response_reg
k141_5116_52	545243.BAEV01000032_gene498	1.91e-103	315.0	COG1181@1|root,COG1181@2|Bacteria,1TP2Y@1239|Firmicutes,248CR@186801|Clostridia,36DR8@31979|Clostridiaceae	186801|Clostridia	F	Belongs to the D-alanine--D-alanine ligase family	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
k141_5116_53	1121324.CLIT_13c02350	3.07e-93	280.0	COG1802@1|root,COG1802@2|Bacteria,1TSV2@1239|Firmicutes,24C0U@186801|Clostridia,25QQ7@186804|Peptostreptococcaceae	186801|Clostridia	K	FCD	ydfH_4	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
k141_5116_54	1151292.QEW_4200	6.61e-93	284.0	COG1947@1|root,COG1947@2|Bacteria,1TPXV@1239|Firmicutes,24898@186801|Clostridia,25QT8@186804|Peptostreptococcaceae	186801|Clostridia	F	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol	ispE	-	2.7.1.148	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05634	RC00002,RC01439	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
k141_5116_55	1286171.EAL2_c18020	2.3e-38	130.0	COG4466@1|root,COG4466@2|Bacteria,1VEQM@1239|Firmicutes,24QN2@186801|Clostridia,25XU3@186806|Eubacteriaceae	186801|Clostridia	S	Biofilm formation stimulator VEG	veg	-	-	-	-	-	-	-	-	-	-	-	VEG
k141_5116_56	1511.CLOST_0929	4.6e-87	267.0	COG1378@1|root,COG1378@2|Bacteria,1TSB2@1239|Firmicutes,25CS5@186801|Clostridia	186801|Clostridia	K	Archaeal transcriptional regulator TrmB	-	-	-	-	-	-	-	-	-	-	-	-	Regulator_TrmB,TrmB
k141_5116_57	1511.CLOST_0928	4.89e-164	465.0	COG0549@1|root,COG0549@2|Bacteria,1TP9H@1239|Firmicutes,2482W@186801|Clostridia,25QD2@186804|Peptostreptococcaceae	186801|Clostridia	E	Amino acid kinase family	arcC	-	2.7.2.2	ko:K00926	ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200	-	R00150,R01395	RC00002,RC00043,RC02803,RC02804	ko00000,ko00001,ko01000	-	-	-	AA_kinase
k141_5116_58	1511.CLOST_0927	2.86e-195	546.0	COG0078@1|root,COG0078@2|Bacteria,1TPF2@1239|Firmicutes,248I5@186801|Clostridia,25SFG@186804|Peptostreptococcaceae	186801|Clostridia	E	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline	argF	-	2.1.3.3	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844	R01398	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS12430	OTCace,OTCace_N
k141_5116_59	1511.CLOST_0926	1.43e-214	602.0	COG2235@1|root,COG2235@2|Bacteria,1TQWS@1239|Firmicutes,249V9@186801|Clostridia,25SER@186804|Peptostreptococcaceae	186801|Clostridia	E	Amidinotransferase	arcA	-	3.5.3.6	ko:K01478	ko00220,ko01100,ko01110,ko01130,map00220,map01100,map01110,map01130	-	R00552	RC00177	ko00000,ko00001,ko01000	-	-	-	Amidinotransf
k141_5116_60	1286171.EAL2_c18040	6.69e-69	218.0	293PP@1|root,2ZR5C@2|Bacteria,1VBW4@1239|Firmicutes,24NKJ@186801|Clostridia	186801|Clostridia	S	UPF0489 domain	-	-	-	-	-	-	-	-	-	-	-	-	UPF0489
k141_5116_61	1286171.EAL2_c02670	2.13e-114	350.0	COG2208@1|root,COG2208@2|Bacteria,1TQY5@1239|Firmicutes,249WB@186801|Clostridia,25XB2@186806|Eubacteriaceae	186801|Clostridia	KT	Sigma factor PP2C-like phosphatases	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	MASE3,PAS_4,PAS_9,SpoIIE
k141_5116_62	391009.Tmel_1183	1.33e-13	68.9	COG1366@1|root,COG1366@2|Bacteria,2GDAN@200918|Thermotogae	200918|Thermotogae	T	PFAM Sulfate transporter antisigma-factor antagonist STAS	-	-	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS
k141_5116_64	584708.Apau_0873	1.61e-65	236.0	COG0643@1|root,COG2198@1|root,COG0643@2|Bacteria,COG2198@2|Bacteria,3T9SQ@508458|Synergistetes	508458|Synergistetes	T	Signal transducing histidine kinase homodimeric	-	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt,P2
k141_5116_66	1121935.AQXX01000126_gene953	5.7e-30	134.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,1XR55@135619|Oceanospirillales	135619|Oceanospirillales	NT	Cache domain	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal,dCache_1
k141_5116_67	500633.CLOHIR_02212	2.05e-94	282.0	COG0564@1|root,COG0564@2|Bacteria,1TX59@1239|Firmicutes,24HTV@186801|Clostridia,25QEF@186804|Peptostreptococcaceae	186801|Clostridia	J	Pseudouridine synthase	rluC	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2
k141_5116_68	1121324.CLIT_13c02280	1.69e-180	505.0	COG1092@1|root,COG1092@2|Bacteria,1TPUD@1239|Firmicutes,2480X@186801|Clostridia,25QYD@186804|Peptostreptococcaceae	186801|Clostridia	J	S-adenosylmethionine-dependent methyltransferase	rlmL_1	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
k141_5116_69	1121324.CLIT_13c02260	2.15e-71	219.0	COG1528@1|root,COG1528@2|Bacteria,1V1BJ@1239|Firmicutes,24FUF@186801|Clostridia,25RG7@186804|Peptostreptococcaceae	186801|Clostridia	P	Iron-storage protein	ftnA	-	1.16.3.2	ko:K02217	-	-	-	-	ko00000,ko01000	-	-	-	Ferritin
k141_5116_70	1121289.JHVL01000005_gene1026	1.61e-67	234.0	COG3290@1|root,COG3290@2|Bacteria,1TQJR@1239|Firmicutes,247YE@186801|Clostridia	186801|Clostridia	T	Signal transduction histidine kinase regulating citrate malate metabolism	-	-	2.7.13.3	ko:K07700	ko02020,map02020	M00486	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,SPOB_a
k141_5116_71	387092.NIS_0518	6.56e-62	225.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,42M0W@68525|delta/epsilon subdivisions,2YMHP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	signal transduction protein containing a membrane domain an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,HAMP,PAS_3,PAS_4,PAS_9
k141_5116_72	1321778.HMPREF1982_00530	5.34e-52	176.0	COG0204@1|root,COG0204@2|Bacteria,1UMJA@1239|Firmicutes,249AV@186801|Clostridia,26A4G@186813|unclassified Clostridiales	186801|Clostridia	I	Phosphate acyltransferases	plsC	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
k141_5116_73	931276.Cspa_c38590	2.21e-37	140.0	COG0561@1|root,COG0561@2|Bacteria,1U3W2@1239|Firmicutes,2486H@186801|Clostridia,36DQB@31979|Clostridiaceae	186801|Clostridia	S	hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
k141_5116_75	1443125.Z962_10495	4.3e-175	503.0	COG2056@1|root,COG2056@2|Bacteria,1TSRY@1239|Firmicutes,24A6E@186801|Clostridia,36FY0@31979|Clostridiaceae	186801|Clostridia	S	Na+-H+ antiporter family	-	-	-	ko:K07084	-	-	-	-	ko00000,ko02000	2.A.8.1.12	-	-	Na_H_antiport_2,Na_H_antiporter
k141_5116_76	1347392.CCEZ01000018_gene1082	1.81e-257	719.0	COG2986@1|root,COG2986@2|Bacteria,1TPCW@1239|Firmicutes,247XP@186801|Clostridia,36DCC@31979|Clostridiaceae	186801|Clostridia	E	Histidine ammonia-lyase	hutH	-	4.3.1.3	ko:K01745	ko00340,ko01100,map00340,map01100	M00045	R01168	RC00361	ko00000,ko00001,ko00002,ko01000	-	-	-	Lyase_aromatic
k141_5116_77	1321778.HMPREF1982_01119	2.1e-165	472.0	COG0180@1|root,COG0180@2|Bacteria,1TPY7@1239|Firmicutes,248RC@186801|Clostridia,267IZ@186813|unclassified Clostridiales	186801|Clostridia	J	tRNA synthetases class I (W and Y)	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
k141_5116_79	864565.HMPREF0379_2003	1.48e-07	50.8	COG0425@1|root,COG0425@2|Bacteria	2|Bacteria	O	sulfur carrier activity	-	-	-	-	-	-	-	-	-	-	-	-	DrsE,TusA
k141_5116_80	318464.IO99_02240	2.13e-165	473.0	COG2391@1|root,COG2391@2|Bacteria,1TPWG@1239|Firmicutes,249KU@186801|Clostridia,36GD5@31979|Clostridiaceae	186801|Clostridia	S	Sulphur transport	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
k141_5116_82	545243.BAEV01000086_gene2332	1.92e-69	237.0	COG0539@1|root,COG0761@1|root,COG0539@2|Bacteria,COG0761@2|Bacteria,1TQ9N@1239|Firmicutes,247UK@186801|Clostridia,36DPA@31979|Clostridiaceae	186801|Clostridia	J	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis	ispH	-	1.17.7.4	ko:K02945,ko:K03527	ko00900,ko01100,ko01110,ko01130,ko03010,map00900,map01100,map01110,map01130,map03010	M00096,M00178	R05884,R08210	RC01137,RC01487	br01610,ko00000,ko00001,ko00002,ko01000,ko03011	-	-	-	LYTB,S1
k141_5116_83	857293.CAAU_0679	1.27e-141	431.0	COG0840@1|root,COG0840@2|Bacteria,1TSP5@1239|Firmicutes,24AUD@186801|Clostridia,36EC7@31979|Clostridiaceae	186801|Clostridia	NT	chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HNOB,MCPsignal
k141_5116_84	865861.AZSU01000009_gene575	3.35e-172	498.0	COG0624@1|root,COG0624@2|Bacteria,1TPEG@1239|Firmicutes,247SK@186801|Clostridia,36DX8@31979|Clostridiaceae	186801|Clostridia	E	Dipeptidase	-	-	3.5.1.18	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R02734	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
k141_5116_86	865861.AZSU01000002_gene2572	2.14e-27	103.0	2E6A2@1|root,330XY@2|Bacteria,1VISZ@1239|Firmicutes,24QK3@186801|Clostridia,36UF4@31979|Clostridiaceae	186801|Clostridia	S	Coenzyme PQQ synthesis protein D (PqqD)	-	-	-	-	-	-	-	-	-	-	-	-	PqqD
k141_5116_87	1304284.L21TH_1909	0.0	886.0	COG1297@1|root,COG1297@2|Bacteria,1TQJP@1239|Firmicutes,247JY@186801|Clostridia,36DEB@31979|Clostridiaceae	186801|Clostridia	S	oligopeptide transporter, OPT family	-	-	-	-	-	-	-	-	-	-	-	-	OPT
k141_3088_1	1307761.L21SP2_2649	2.42e-210	610.0	COG0610@1|root,COG0610@2|Bacteria,2J5UU@203691|Spirochaetes	203691|Spirochaetes	V	Subunit R is required for both nuclease and ATPase activities, but not for modification	hsdR	-	3.1.21.3	ko:K01153	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	DUF3387,EcoR124_C,HSDR_N,ResIII
k141_76_1	933262.AXAM01000010_gene1346	2.17e-64	207.0	COG0177@1|root,COG0177@2|Bacteria,1RAK3@1224|Proteobacteria,42M4V@68525|delta/epsilon subdivisions,2WPRX@28221|Deltaproteobacteria,2MJJR@213118|Desulfobacterales	28221|Deltaproteobacteria	L	Protein of unknown function (DUF2400)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2400
k141_76_2	648996.Theam_0543	3.89e-21	93.2	COG2067@1|root,COG2067@2|Bacteria,2G47R@200783|Aquificae	200783|Aquificae	I	Outer membrane protein transport protein (OMPP1/FadL/TodX)	-	-	-	ko:K06076	-	-	-	-	ko00000,ko02000	1.B.9	-	-	Toluene_X
k141_4444_2	526222.Desal_2053	2.71e-244	686.0	COG1785@1|root,COG1785@2|Bacteria,1MXI2@1224|Proteobacteria,42N40@68525|delta/epsilon subdivisions,2WKUV@28221|Deltaproteobacteria,2M83Q@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	Belongs to the alkaline phosphatase family	-	-	3.1.3.1	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	M00126	R02135,R04620	RC00017	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	-	-	-	Alk_phosphatase
k141_4444_3	470704.XP_007760032.1	3.04e-05	54.3	2EG3Z@1|root,2SM5C@2759|Eukaryota,39ZK3@33154|Opisthokonta,3P1EZ@4751|Fungi,3QPV1@4890|Ascomycota,20E79@147545|Eurotiomycetes,3MV40@451870|Chaetothyriomycetidae	4751|Fungi	S	ankyrin repeats	-	-	-	-	-	-	-	-	-	-	-	-	Ank_2,NACHT
k141_3423_1	1313304.CALK_0197	1.21e-100	333.0	COG4191@1|root,COG4191@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
k141_4446_1	1121396.KB892990_gene4510	7.62e-89	285.0	COG1033@1|root,COG1033@2|Bacteria,1MUE1@1224|Proteobacteria,42ME2@68525|delta/epsilon subdivisions,2WJRI@28221|Deltaproteobacteria,2MNE6@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Sterol-sensing domain of SREBP cleavage-activation	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
k141_2389_1	1121405.dsmv_1647	5.54e-99	331.0	COG1643@1|root,COG1643@2|Bacteria,1MUEQ@1224|Proteobacteria,42MD4@68525|delta/epsilon subdivisions,2WJ7Z@28221|Deltaproteobacteria,2MIAK@213118|Desulfobacterales	28221|Deltaproteobacteria	L	TIGRFAM ATP-dependent helicase HrpA	hrpA	-	3.6.4.13	ko:K03578,ko:K03579	-	-	-	-	ko00000,ko01000	-	-	-	AAA_19,DEAD,DUF3418,HA2,Helicase_C,OB_NTP_bind
k141_1747_2	1348635.BBJY01000006_gene324	4.28e-292	811.0	COG1299@1|root,COG1445@1|root,COG1299@2|Bacteria,COG1445@2|Bacteria,1MXFN@1224|Proteobacteria,1RMZC@1236|Gammaproteobacteria,1XSC5@135623|Vibrionales	135623|Vibrionales	G	COG1445 Phosphotransferase system fructose-specific component IIB	fruA	-	2.7.1.202	ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	M00273	R03232	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.2.1	-	-	PTS_EIIC,PTS_IIB
k141_2835_4	945550.VISI1226_16303	6.3e-88	266.0	COG3159@1|root,COG3159@2|Bacteria,1R4BP@1224|Proteobacteria,1S9SC@1236|Gammaproteobacteria,1Y2KJ@135623|Vibrionales	135623|Vibrionales	S	Protein of unknown function, DUF484	-	-	-	ko:K09921	-	-	-	-	ko00000	-	-	-	DUF484
k141_2835_7	1280001.BAOA01000112_gene4668	1.12e-49	159.0	COG1965@1|root,COG1965@2|Bacteria,1RH9A@1224|Proteobacteria,1S5UP@1236|Gammaproteobacteria,1XXUN@135623|Vibrionales	135623|Vibrionales	P	Belongs to the frataxin family	cyaY	GO:0003674,GO:0003824,GO:0004322,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006790,GO:0006807,GO:0006873,GO:0006875,GO:0006879,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008198,GO:0008199,GO:0009987,GO:0016043,GO:0016226,GO:0016491,GO:0016530,GO:0016722,GO:0016724,GO:0018282,GO:0018283,GO:0019538,GO:0019725,GO:0022607,GO:0030003,GO:0031163,GO:0033554,GO:0034599,GO:0034986,GO:0036211,GO:0042221,GO:0042592,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0046916,GO:0048037,GO:0048878,GO:0050801,GO:0050896,GO:0051186,GO:0051536,GO:0051537,GO:0051540,GO:0051716,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0071704,GO:0071840,GO:0098771,GO:0140104,GO:1901564	-	ko:K06202	-	-	-	-	ko00000	-	-	-	Frataxin_Cyay
k141_2835_8	55601.VANGNB10_cI0072	0.0	1393.0	COG3072@1|root,COG3072@2|Bacteria,1PI5T@1224|Proteobacteria,1RMPZ@1236|Gammaproteobacteria,1XUEA@135623|Vibrionales	135623|Vibrionales	F	Adenylate cyclase	cyaA	-	4.6.1.1	ko:K05851	ko00230,ko02026,ko05111,map00230,map02026,map05111	-	R00089,R00434	RC00295	ko00000,ko00001,ko01000	-	-	-	Adenyl_cycl_N,Adenylate_cycl
k141_2835_9	1191299.AJYX01000037_gene3319	2.66e-176	496.0	COG0181@1|root,COG0181@2|Bacteria,1MU56@1224|Proteobacteria,1RMQ8@1236|Gammaproteobacteria,1XSM4@135623|Vibrionales	135623|Vibrionales	H	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps	hemC	GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.61	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084	RC02317	ko00000,ko00001,ko00002,ko01000	-	-	-	Porphobil_deam,Porphobil_deamC
k141_2835_10	1038922.PflQ2_0233	1.65e-20	98.6	COG1587@1|root,COG2959@1|root,COG1587@2|Bacteria,COG2959@2|Bacteria,1MY3A@1224|Proteobacteria,1RNJY@1236|Gammaproteobacteria,1YPKY@136843|Pseudomonas fluorescens group	1236|Gammaproteobacteria	H	HemX, putative uroporphyrinogen-III C-methyltransferase	hemX	-	2.1.1.107,4.2.1.75	ko:K02496,ko:K13543	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03165,R03194	RC00003,RC00871,RC01861	ko00000,ko00001,ko00002,ko01000	-	-	iAF1260.b3803,iBWG_1329.BWG_3482,iECDH1ME8569_1439.ECDH1ME8569_3682,iECUMN_1333.ECUMN_4327,iECs_1301.ECs4733,iEcDH1_1363.EcDH1_4176,iJO1366.b3803,iJR904.b3803,iPC815.YPO3851,iUMN146_1321.UM146_19140,iY75_1357.Y75_RS18060,iZ_1308.Z5317	HemX
k141_2835_11	675816.VIA_000058	6.17e-151	439.0	COG2959@1|root,COG2959@2|Bacteria,1MY3A@1224|Proteobacteria,1RNJY@1236|Gammaproteobacteria,1XU9X@135623|Vibrionales	135623|Vibrionales	H	Uroporphyrin-III C-methyltransferase	hemX	-	2.1.1.107	ko:K02496	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03194	RC00003,RC00871	ko00000,ko00001,ko00002,ko01000	-	-	-	HemX
k141_2835_12	1051646.VITU9109_04142	1.1e-22	95.9	COG3071@1|root,COG3071@2|Bacteria,1MU7A@1224|Proteobacteria,1RMRG@1236|Gammaproteobacteria,1XT4E@135623|Vibrionales	135623|Vibrionales	H	enzyme of heme biosynthesis	hemY	-	-	ko:K02498	-	-	-	-	ko00000	-	-	-	HemY_N,TPR_16,TPR_19,TPR_2
k141_1236_1	177439.DP1296	1.13e-259	720.0	COG1115@1|root,COG1115@2|Bacteria,1MUI3@1224|Proteobacteria,42MG1@68525|delta/epsilon subdivisions,2WKHE@28221|Deltaproteobacteria,2MMGH@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Sodium:alanine symporter family	-	-	-	ko:K03310	-	-	-	-	ko00000	2.A.25	-	-	Na_Ala_symp
k141_3555_1	879212.DespoDRAFT_01377	8.39e-51	166.0	COG0344@1|root,COG0344@2|Bacteria,1RD4Z@1224|Proteobacteria,42QQP@68525|delta/epsilon subdivisions,2WQFY@28221|Deltaproteobacteria,2MPUF@213118|Desulfobacterales	28221|Deltaproteobacteria	I	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP	plsY	-	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	G3P_acyltransf
k141_3555_2	1121396.KB892935_gene3843	1.38e-56	183.0	2F6TN@1|root,33Z9T@2|Bacteria,1NYCY@1224|Proteobacteria,430CR@68525|delta/epsilon subdivisions,2WVNC@28221|Deltaproteobacteria,2MNPG@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Polyketide synthase dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	PS-DH
k141_2208_1	1304885.AUEY01000068_gene1408	1.42e-27	106.0	COG3018@1|root,COG3018@2|Bacteria,1RGG9@1224|Proteobacteria,42T4T@68525|delta/epsilon subdivisions,2WPU7@28221|Deltaproteobacteria,2MKBS@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Protein conserved in bacteria	-	-	-	ko:K09860	-	-	-	-	ko00000	-	-	-	-
k141_4603_1	1304885.AUEY01000004_gene971	5.09e-78	261.0	COG0419@1|root,COG0419@2|Bacteria,1MVTQ@1224|Proteobacteria,42NVV@68525|delta/epsilon subdivisions,2WJIZ@28221|Deltaproteobacteria,2MIHG@213118|Desulfobacterales	28221|Deltaproteobacteria	L	TIGRFAM exonuclease SbcC	sbcC	-	-	ko:K03546	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,SbcCD_C
k141_1238_1	96561.Dole_1567	4.18e-95	288.0	COG0547@1|root,COG0547@2|Bacteria,1MUPV@1224|Proteobacteria,42NRG@68525|delta/epsilon subdivisions,2WJRU@28221|Deltaproteobacteria,2MIMY@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)	trpD	GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.4.2.18,4.1.3.27	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R00985,R00986,R01073	RC00010,RC00440,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2495	GATase,Glycos_trans_3N,Glycos_transf_3
k141_4217_1	1121405.dsmv_2551	7.79e-23	100.0	COG2844@1|root,COG2844@2|Bacteria,1MV54@1224|Proteobacteria,42MN5@68525|delta/epsilon subdivisions,2WINN@28221|Deltaproteobacteria,2MI1W@213118|Desulfobacterales	28221|Deltaproteobacteria	O	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen	glnD	-	2.7.7.59	ko:K00990	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	-	-	-	ACT,DUF294,GlnD_UR_UTase,GlnE,HD,NTP_transf_2
k141_4217_2	1265505.ATUG01000001_gene4340	2.64e-54	172.0	COG0347@1|root,COG0347@2|Bacteria,1RGWK@1224|Proteobacteria,42SJJ@68525|delta/epsilon subdivisions,2WP4E@28221|Deltaproteobacteria,2MK8A@213118|Desulfobacterales	28221|Deltaproteobacteria	K	Belongs to the P(II) protein family	-	-	-	ko:K04751	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	P-II
k141_4217_3	596151.DesfrDRAFT_3192	9.45e-162	467.0	COG0004@1|root,COG0004@2|Bacteria,1NR9F@1224|Proteobacteria,42MFT@68525|delta/epsilon subdivisions,2WIXC@28221|Deltaproteobacteria,2M7WT@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	TIGRFAM Ammonium transporter	amt	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
k141_4217_4	933262.AXAM01000040_gene1225	4.44e-276	762.0	COG0174@1|root,COG0174@2|Bacteria,1MUGQ@1224|Proteobacteria,42M7A@68525|delta/epsilon subdivisions,2WJ8P@28221|Deltaproteobacteria,2MHRE@213118|Desulfobacterales	28221|Deltaproteobacteria	E	TIGRFAM glutamine synthetase, type I	glnA	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
k141_4217_5	1211035.CD30_11900	1.33e-08	55.8	COG0745@1|root,COG0745@2|Bacteria,1TPZ0@1239|Firmicutes,4HA7D@91061|Bacilli,3IX9W@400634|Lysinibacillus	91061|Bacilli	K	Transcriptional regulator	resD	-	-	ko:K07775	ko02020,map02020	M00458	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
k141_2836_1	1265505.ATUG01000001_gene4789	4.51e-88	265.0	COG1136@1|root,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,42PYJ@68525|delta/epsilon subdivisions,2WKHY@28221|Deltaproteobacteria,2MJ28@213118|Desulfobacterales	28221|Deltaproteobacteria	V	PFAM ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
k141_2836_2	439235.Dalk_0592	2.61e-58	200.0	2C2F5@1|root,32WND@2|Bacteria,1ND6R@1224|Proteobacteria,42Q4T@68525|delta/epsilon subdivisions,2WK9F@28221|Deltaproteobacteria,2MHXS@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_3556_1	1304885.AUEY01000028_gene2789	1.75e-148	434.0	COG0460@1|root,COG0460@2|Bacteria,1MUDC@1224|Proteobacteria,42MGS@68525|delta/epsilon subdivisions,2WJ1K@28221|Deltaproteobacteria,2MINV@213118|Desulfobacterales	28221|Deltaproteobacteria	E	PFAM homoserine dehydrogenase	hom	-	1.1.1.3	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00017,M00018	R01773,R01775	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,Homoserine_dh,NAD_binding_3
k141_3556_2	1265505.ATUG01000003_gene698	9.14e-20	84.3	COG0560@1|root,COG0560@2|Bacteria,1MZPG@1224|Proteobacteria,42Q82@68525|delta/epsilon subdivisions,2WMBU@28221|Deltaproteobacteria,2MI8W@213118|Desulfobacterales	28221|Deltaproteobacteria	E	phosphoserine phosphatase homoserine phosphotransferase bifunctional protein	-	-	2.7.1.39,3.1.3.3	ko:K02203	ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00680,map01100,map01110,map01120,map01130,map01230	M00018	R00582,R01771	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HAD
k141_3557_1	1033737.CAEV01000110_gene1176	1.02e-62	211.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247Q0@186801|Clostridia,36E4P@31979|Clostridiaceae	186801|Clostridia	V	ABC transporter	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
k141_3558_1	1238450.VIBNISOn1_560115	7.09e-38	142.0	COG0443@1|root,COG0443@2|Bacteria,1MXX7@1224|Proteobacteria,1RP0D@1236|Gammaproteobacteria,1XTBY@135623|Vibrionales	135623|Vibrionales	O	Belongs to the heat shock protein 70 family	-	-	-	-	-	-	-	-	-	-	-	-	DUF3731,HSP70
k141_3558_2	1205908.AKXW01000122_gene304	1.11e-35	135.0	COG0826@1|root,COG0826@2|Bacteria,1MUQG@1224|Proteobacteria,1RN7S@1236|Gammaproteobacteria,1XUBV@135623|Vibrionales	135623|Vibrionales	O	COG0826 Collagenase and related proteases	-	-	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	DUF3656,Peptidase_U32
k141_4219_1	1121403.AUCV01000002_gene571	1.28e-84	261.0	COG0225@1|root,COG0229@1|root,COG0225@2|Bacteria,COG0229@2|Bacteria,1RGWC@1224|Proteobacteria,42N4Z@68525|delta/epsilon subdivisions,2WIKW@28221|Deltaproteobacteria,2MHKB@213118|Desulfobacterales	28221|Deltaproteobacteria	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	-	1.8.4.11,1.8.4.12	ko:K07305,ko:K12267	-	-	-	-	ko00000,ko01000	-	-	-	PMSR,SelR
k141_1239_1	498211.CJA_2520	2.59e-167	537.0	COG1022@1|root,COG5184@1|root,COG5276@1|root,COG1022@2|Bacteria,COG5184@2|Bacteria,COG5276@2|Bacteria,1PG4J@1224|Proteobacteria,1RWXR@1236|Gammaproteobacteria,1FIEH@10|Cellvibrio	1236|Gammaproteobacteria	DZ	Regulator of chromosome condensation (RCC1) repeat	-	-	-	-	-	-	-	-	-	-	-	-	RCC1
k141_4930_1	985665.HPL003_08735	3.43e-217	619.0	COG1263@1|root,COG1264@1|root,COG2190@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,COG2190@2|Bacteria,1TP5X@1239|Firmicutes,4HA0I@91061|Bacilli,26QAW@186822|Paenibacillaceae	91061|Bacilli	G	COG1264 Phosphotransferase system IIB components	-	-	-	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	M00271	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.1.2.11,4.A.1.2.2,4.A.1.2.5,4.A.1.2.6	-	-	PTS_EIIA_1,PTS_EIIB,PTS_EIIC
k141_4930_2	35841.BT1A1_3063	1.5e-116	368.0	COG1263@1|root,COG1264@1|root,COG2190@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,COG2190@2|Bacteria,1TP5X@1239|Firmicutes,4HA0I@91061|Bacilli,1ZC3X@1386|Bacillus	91061|Bacilli	G	phosphotransferase system	-	-	-	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	M00271	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.1.2.11,4.A.1.2.2,4.A.1.2.5,4.A.1.2.6	-	-	PTS_EIIA_1,PTS_EIIB,PTS_EIIC
k141_4930_3	985665.HPL003_08740	1.5e-103	310.0	COG3711@1|root,COG3711@2|Bacteria,1TT5A@1239|Firmicutes,4HC5Y@91061|Bacilli,26UWA@186822|Paenibacillaceae	91061|Bacilli	K	CAT RNA binding domain	-	-	-	ko:K03488	-	-	-	-	ko00000,ko03000	-	-	-	CAT_RBD,PRD
k141_4930_4	985665.HPL003_08745	7.02e-278	768.0	COG2723@1|root,COG2723@2|Bacteria,1TP19@1239|Firmicutes,4HA1W@91061|Bacilli,26QRQ@186822|Paenibacillaceae	91061|Bacilli	G	Belongs to the glycosyl hydrolase 1 family	-	-	3.2.1.86	ko:K01223	ko00010,ko00500,map00010,map00500	-	R00839,R05133,R05134	RC00049,RC00171,RC00714	ko00000,ko00001,ko01000	-	GT1	-	Glyco_hydro_1
k141_4930_5	675813.VIB_000007	6.33e-178	499.0	COG0384@1|root,COG0384@2|Bacteria,1MUAS@1224|Proteobacteria,1S0T9@1236|Gammaproteobacteria,1Y2CH@135623|Vibrionales	135623|Vibrionales	S	phenazine biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	PhzC-PhzF
k141_4930_6	29495.EA26_08905	7.48e-130	376.0	COG2267@1|root,COG2267@2|Bacteria,1NH7M@1224|Proteobacteria,1THE5@1236|Gammaproteobacteria,1XUQ0@135623|Vibrionales	135623|Vibrionales	I	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
k141_4930_7	29495.EA26_08900	2.79e-115	342.0	2F1JP@1|root,33UK3@2|Bacteria,1NUD0@1224|Proteobacteria,1SNTF@1236|Gammaproteobacteria,1XT2I@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_4930_8	491952.Mar181_1091	2.31e-124	357.0	COG0625@1|root,COG0625@2|Bacteria,1RA4M@1224|Proteobacteria,1S2K3@1236|Gammaproteobacteria,1XPGR@135619|Oceanospirillales	135619|Oceanospirillales	O	Glutathione S-transferase	-	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C,GST_C_2,GST_N_3
k141_4930_9	29495.EA26_13470	9.29e-76	258.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,1XWA3@135623|Vibrionales	135623|Vibrionales	T	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal
k141_4930_10	29495.EA26_08900	8.37e-116	342.0	2F1JP@1|root,33UK3@2|Bacteria,1NUD0@1224|Proteobacteria,1SNTF@1236|Gammaproteobacteria,1XT2I@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_4930_11	1051646.VITU9109_05481	2.79e-123	360.0	COG2267@1|root,COG2267@2|Bacteria,1NH7M@1224|Proteobacteria,1THE5@1236|Gammaproteobacteria,1XUQ0@135623|Vibrionales	135623|Vibrionales	I	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
k141_4930_12	29495.EA26_08910	5.85e-17	74.3	2B5UQ@1|root,31YQF@2|Bacteria,1QKCX@1224|Proteobacteria,1TIGH@1236|Gammaproteobacteria,1XZ37@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_4930_13	526222.Desal_1237	4.15e-94	288.0	2B4WN@1|root,31XPD@2|Bacteria,1NK76@1224|Proteobacteria,432QH@68525|delta/epsilon subdivisions,2WXWN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_4930_14	1224318.DT73_16090	8.53e-297	819.0	COG3711@1|root,COG3711@2|Bacteria,1PKXV@1224|Proteobacteria,1RSDI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	GK	transcriptional antiterminator	-	-	-	ko:K02538,ko:K03491	-	-	-	-	ko00000,ko03000	-	-	-	HTH_11,Mga,PRD,PTS_EIIA_2,PTS_IIB
k141_4930_15	1441930.Z042_13715	6.01e-71	217.0	COG1762@1|root,COG1762@2|Bacteria,1RA06@1224|Proteobacteria,1S2SM@1236|Gammaproteobacteria,4053S@613|Serratia	1236|Gammaproteobacteria	G	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2	fruA_2	-	2.7.1.202	ko:K02768	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	M00273	R03232	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.2.1	-	-	PTS_EIIA_2
k141_1505_4	1511.CLOST_2001	2.21e-149	430.0	COG3641@1|root,COG3641@2|Bacteria,1TS5F@1239|Firmicutes,247P0@186801|Clostridia,25QPN@186804|Peptostreptococcaceae	186801|Clostridia	S	Phosphotransferase system, EIIC	-	-	-	ko:K07035	-	-	-	-	ko00000	-	-	-	PTS_EIIC_2
k141_1505_5	1499683.CCFF01000002_gene3	7.23e-48	160.0	COG1827@1|root,COG1827@2|Bacteria,1V6EY@1239|Firmicutes,24JF2@186801|Clostridia,36IFU@31979|Clostridiaceae	186801|Clostridia	S	3H domain	niaR	-	-	ko:K07105	-	-	-	-	ko00000	-	-	-	3H,HTH_11
k141_4931_1	1121396.KB893085_gene337	3.17e-44	150.0	2EP1E@1|root,33GN9@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	ZinT
k141_4606_1	378806.STAUR_1545	8.18e-07	48.5	2B9U6@1|root,32372@2|Bacteria,1RHAQ@1224|Proteobacteria,43DJF@68525|delta/epsilon subdivisions,2X8QQ@28221|Deltaproteobacteria,2Z2FA@29|Myxococcales	28221|Deltaproteobacteria	S	T4-like virus tail tube protein gp19	-	-	-	-	-	-	-	-	-	-	-	-	Phage_T4_gp19
k141_4606_4	1144319.PMI16_01955	3.64e-59	193.0	COG1652@1|root,COG1652@2|Bacteria,1RF5U@1224|Proteobacteria,2VV64@28216|Betaproteobacteria	28216|Betaproteobacteria	S	LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_4606_5	398720.MED217_08615	4.92e-17	82.4	COG3501@1|root,COG3501@2|Bacteria,4NFPB@976|Bacteroidetes,1HZN7@117743|Flavobacteriia	976|Bacteroidetes	S	Rhs element Vgr protein	-	-	-	-	-	-	-	-	-	-	-	-	Phage_GPD
k141_4607_1	998088.B565_3852	6.98e-29	116.0	COG2199@1|root,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,1RMA9@1236|Gammaproteobacteria,1Y5Z9@135624|Aeromonadales	135624|Aeromonadales	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
k141_4220_1	555779.Dthio_PD0736	1.41e-109	327.0	COG1943@1|root,COG1943@2|Bacteria,1MVUV@1224|Proteobacteria,43B13@68525|delta/epsilon subdivisions,2WS1C@28221|Deltaproteobacteria	1224|Proteobacteria	L	COG1943 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_1240_1	1304885.AUEY01000017_gene3730	1.46e-278	787.0	COG0187@1|root,COG0187@2|Bacteria,1MVKT@1224|Proteobacteria,42M7M@68525|delta/epsilon subdivisions,2WJ9X@28221|Deltaproteobacteria,2MHSK@213118|Desulfobacterales	28221|Deltaproteobacteria	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
k141_251_2	945550.VISI1226_02592	1.61e-253	698.0	COG0192@1|root,COG0192@2|Bacteria,1MUFQ@1224|Proteobacteria,1RNV6@1236|Gammaproteobacteria,1XSPC@135623|Vibrionales	135623|Vibrionales	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006556,GO:0006732,GO:0006790,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0044237,GO:0044249,GO:0044272,GO:0044424,GO:0044444,GO:0044464,GO:0046500,GO:0051186,GO:0051188,GO:0071704,GO:1901576	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
k141_251_3	672.VV93_v1c25710	1.35e-58	187.0	COG3091@1|root,COG3091@2|Bacteria,1RJW4@1224|Proteobacteria,1S70F@1236|Gammaproteobacteria,1XW7P@135623|Vibrionales	135623|Vibrionales	S	Belongs to the SprT family	sprT	-	-	ko:K02742	-	-	-	-	ko00000	-	-	-	SprT-like,Zn_ribbon_SprT
k141_251_4	55601.VANGNB10_cI0341c	3.38e-134	384.0	COG1385@1|root,COG1385@2|Bacteria,1MXCU@1224|Proteobacteria,1RPBN@1236|Gammaproteobacteria,1XUB1@135623|Vibrionales	135623|Vibrionales	J	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit	rsmE	-	2.1.1.193	ko:K09761	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_RNA
k141_251_5	1348635.BBJY01000021_gene2806	5.17e-203	565.0	COG0189@1|root,COG0189@2|Bacteria,1MVUA@1224|Proteobacteria,1RMU0@1236|Gammaproteobacteria,1XSEZ@135623|Vibrionales	135623|Vibrionales	H	Belongs to the prokaryotic GSH synthase family	gshB	GO:0003674,GO:0003824,GO:0004363,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006518,GO:0006575,GO:0006749,GO:0006750,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0019184,GO:0034641,GO:0042398,GO:0043043,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044424,GO:0044464,GO:0051186,GO:0051188,GO:0071704,GO:1901564,GO:1901566,GO:1901576	6.3.2.3	ko:K01920	ko00270,ko00480,ko01100,map00270,map00480,map01100	M00118	R00497,R10994	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	GSH-S_ATP,GSH-S_N
k141_251_6	675815.VOA_001895	1.22e-104	305.0	COG1678@1|root,COG1678@2|Bacteria,1RCXM@1224|Proteobacteria,1S3YV@1236|Gammaproteobacteria,1XU0H@135623|Vibrionales	135623|Vibrionales	K	Belongs to the UPF0301 (AlgH) family	yqgE	-	-	ko:K07735	-	-	-	-	ko00000,ko03000	-	-	-	DUF179
k141_251_7	675816.VIA_000187	9.01e-89	261.0	COG0816@1|root,COG0816@2|Bacteria,1RDHZ@1224|Proteobacteria,1S96Q@1236|Gammaproteobacteria,1XWVP@135623|Vibrionales	135623|Vibrionales	L	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA	yqgF	GO:0000966,GO:0000967,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	-	ko:K07447	-	-	-	-	ko00000,ko01000	-	-	-	RuvX
k141_251_8	1121013.P873_13245	3.38e-106	333.0	COG2805@1|root,COG5008@1|root,COG2805@2|Bacteria,COG5008@2|Bacteria,1MU3J@1224|Proteobacteria,1T393@1236|Gammaproteobacteria	1236|Gammaproteobacteria	NU	Type II/IV secretion system protein	-	-	-	ko:K12203	-	-	-	-	ko00000,ko02044	3.A.7.10.1,3.A.7.9.1	-	-	T2SSE
k141_251_9	223926.28807626	6.45e-117	340.0	COG0325@1|root,COG0325@2|Bacteria,1MWN7@1224|Proteobacteria,1RNPM@1236|Gammaproteobacteria,1XT7U@135623|Vibrionales	135623|Vibrionales	S	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis	yggS	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0008144,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363	-	ko:K06997	-	-	-	-	ko00000	-	-	-	Ala_racemase_N
k141_251_10	1268239.PALB_7860	4.01e-08	54.3	COG0345@1|root,COG0345@2|Bacteria,1R5J1@1224|Proteobacteria,1RNQK@1236|Gammaproteobacteria,2PZCX@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	E	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline	proC	GO:0003674,GO:0003824,GO:0004735,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0017144,GO:0018130,GO:0019752,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0055114,GO:0055129,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.5.1.2	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	M00015	R01248,R01251,R03291,R03293	RC00054,RC00083	ko00000,ko00001,ko00002,ko01000	-	-	iSBO_1134.SBO_0282,ic_1306.c0493	F420_oxidored,P5CR_dimer
k141_1241_1	221988.MS2113	3.35e-42	152.0	COG1373@1|root,COG1373@2|Bacteria,1R3UA@1224|Proteobacteria,1SAYB@1236|Gammaproteobacteria,1Y7E9@135625|Pasteurellales	135625|Pasteurellales	S	AAA superfamily	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
k141_1241_2	1027273.GZ77_21225	2.29e-06	50.4	COG5499@1|root,COG5499@2|Bacteria,1MZHS@1224|Proteobacteria,1S4IJ@1236|Gammaproteobacteria,1XM1E@135619|Oceanospirillales	135619|Oceanospirillales	K	transcription regulator containing HTH domain	-	-	-	ko:K18831	-	-	-	-	ko00000,ko02048,ko03000	-	-	-	HTH_3
k141_1242_1	1502851.FG93_01430	1.15e-06	53.1	COG0154@1|root,COG0154@2|Bacteria,1MU51@1224|Proteobacteria,2TS1E@28211|Alphaproteobacteria,3JT66@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	J	Amidase	-	-	3.5.1.4	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	-	R02540,R03096,R03180,R03909,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000	-	-	-	Amidase
k141_1242_2	1504981.KO116_0304	1.21e-31	119.0	COG1234@1|root,COG1234@2|Bacteria,1Q4PW@1224|Proteobacteria,1RR5K@1236|Gammaproteobacteria,1XIX8@135619|Oceanospirillales	135619|Oceanospirillales	S	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA	rnz	-	3.1.26.11	ko:K00784	ko03013,map03013	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	Lactamase_B_2
k141_2210_1	1348635.BBJY01000009_gene1647	2.31e-168	478.0	COG4143@1|root,COG4143@2|Bacteria,1MUBB@1224|Proteobacteria,1RMQ9@1236|Gammaproteobacteria,1XT2T@135623|Vibrionales	135623|Vibrionales	P	COG4143 ABC-type thiamine transport system, periplasmic component	tbpA	-	-	ko:K02064	ko02010,map02010	M00191	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.19	-	-	SBP_bac_1,SBP_bac_6
k141_2210_2	754436.JCM19237_2947	2.39e-125	359.0	COG0163@1|root,COG0163@2|Bacteria,1RA0P@1224|Proteobacteria,1RPN1@1236|Gammaproteobacteria,1XSI5@135623|Vibrionales	135623|Vibrionales	H	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN	ubiX	GO:0003674,GO:0003824,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008694,GO:0009058,GO:0009108,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663	2.5.1.129	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	M00117	R01238,R02952,R03367,R04985,R04986,R11225	RC00391,RC00814,RC03392	ko00000,ko00001,ko00002,ko01000	-	-	-	Flavoprotein
k141_2210_3	1517681.HW45_19300	1.67e-268	741.0	COG0773@1|root,COG0773@2|Bacteria,1MUC5@1224|Proteobacteria,1RMMT@1236|Gammaproteobacteria,1XTVH@135623|Vibrionales	135623|Vibrionales	M	Reutilizes the intact tripeptide L-alanyl-gamma-D- glutamyl-meso-diaminopimelate by linking it to UDP-N- acetylmuramate	mpl	-	6.3.2.45	ko:K02558	-	-	-	-	ko00000,ko01000	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
k141_2210_4	29495.EA26_19470	3.27e-214	595.0	COG0158@1|root,COG0158@2|Bacteria,1MW0E@1224|Proteobacteria,1RNFF@1236|Gammaproteobacteria,1XT96@135623|Vibrionales	135623|Vibrionales	G	Belongs to the FBPase class 1 family	fbp	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005984,GO:0005985,GO:0005986,GO:0005996,GO:0006000,GO:0006002,GO:0006006,GO:0006094,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0019318,GO:0019319,GO:0019637,GO:0030388,GO:0034637,GO:0042132,GO:0042578,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0046364,GO:0050308,GO:0071704,GO:1901135,GO:1901576	3.1.3.11	ko:K03841	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko04152,ko04910,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map04152,map04910	M00003,M00165,M00167,M00344	R00762,R04780	RC00017	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	FBPase
k141_2210_5	1123034.JMKP01000008_gene434	4.6e-106	308.0	COG0221@1|root,COG0221@2|Bacteria,1RA2F@1224|Proteobacteria,1RPVD@1236|Gammaproteobacteria,3NJX9@468|Moraxellaceae	1236|Gammaproteobacteria	C	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions	ppa	GO:0000287,GO:0003674,GO:0003824,GO:0004427,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006793,GO:0008150,GO:0008152,GO:0008270,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0043167,GO:0043169,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050355	3.6.1.1	ko:K01507	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	iJN746.PP_0538,iPC815.YPO3521	Pyrophosphatase
k141_2210_6	675815.VOA_003387	2.56e-49	159.0	COG2105@1|root,COG2105@2|Bacteria,1N94Q@1224|Proteobacteria,1SEE3@1236|Gammaproteobacteria,1XXWK@135623|Vibrionales	135623|Vibrionales	S	Gamma-glutamyl cyclotransferase, AIG2-like	-	-	-	-	-	-	-	-	-	-	-	-	GGACT
k141_3900_2	675813.VIB_001118	2.9e-75	238.0	COG0451@1|root,COG0451@2|Bacteria,1MWVJ@1224|Proteobacteria,1RNDT@1236|Gammaproteobacteria,1XTJV@135623|Vibrionales	135623|Vibrionales	GM	COG0451 Nucleoside-diphosphate-sugar epimerases	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase,NAD_binding_10,RmlD_sub_bind
k141_3900_3	1187848.AJYQ01000066_gene3563	2.83e-111	323.0	COG1435@1|root,COG1435@2|Bacteria,1NJR4@1224|Proteobacteria,1RPCK@1236|Gammaproteobacteria,1XT1V@135623|Vibrionales	135623|Vibrionales	F	Thymidine kinase	tdk	GO:0003674,GO:0003824,GO:0004797,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006259,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009120,GO:0009123,GO:0009124,GO:0009157,GO:0009162,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019136,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046104,GO:0046125,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0090304,GO:0090407,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657	2.7.1.21	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01567,R02099,R08233	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	TK
k141_3900_5	674977.VMC_31600	1.33e-139	399.0	COG4106@1|root,COG4106@2|Bacteria,1QTS9@1224|Proteobacteria,1T1FG@1236|Gammaproteobacteria,1XSJZ@135623|Vibrionales	135623|Vibrionales	H	Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM)	cmoA	-	-	ko:K15256	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_11,Methyltransf_25
k141_3900_6	1238450.VIBNISOn1_50028	2.7e-196	548.0	COG0500@1|root,COG0500@2|Bacteria,1MVSK@1224|Proteobacteria,1RMQY@1236|Gammaproteobacteria,1XSY3@135623|Vibrionales	135623|Vibrionales	J	Catalyzes carboxymethyl transfer from carboxy-S- adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs	cmoB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044464	-	ko:K15257	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_9
k141_4221_1	948565.AFFP02000009_gene646	1.84e-154	452.0	COG1070@1|root,COG1070@2|Bacteria,1PT3G@1224|Proteobacteria,1RRVW@1236|Gammaproteobacteria,1Y7Y5@135625|Pasteurellales	135625|Pasteurellales	G	Belongs to the FGGY kinase family	fucK	-	2.7.1.51	ko:K00879	ko00051,ko01120,map00051,map01120	-	R03241	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	FGGY_C,FGGY_N
k141_4221_2	1278971.AOGF01000003_gene1391	1.1e-65	203.0	COG4154@1|root,COG4154@2|Bacteria,1RJ03@1224|Proteobacteria,1S27Q@1236|Gammaproteobacteria,1Y8P4@135625|Pasteurellales	135625|Pasteurellales	G	Involved in the anomeric conversion of L-fucose	fucU	-	5.1.3.29	ko:K02431	-	-	R10764	RC00563	ko00000,ko01000	-	-	-	RbsD_FucU
k141_4221_3	948565.AFFP02000009_gene648	8.2e-119	343.0	COG0235@1|root,COG0235@2|Bacteria,1MW7B@1224|Proteobacteria,1RPIK@1236|Gammaproteobacteria,1Y8BZ@135625|Pasteurellales	135625|Pasteurellales	G	Catalyzes the cleavage of L-fuculose 1-phosphate to glycerone phosphate and L-lactaldehyde	fucA	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0008150,GO:0008152,GO:0009056,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0019321,GO:0019323,GO:0044238,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0071704,GO:1901575	4.1.2.17	ko:K01628	ko00051,ko01120,map00051,map01120	-	R02262	RC00603,RC00604	ko00000,ko00001,ko01000	-	-	-	Aldolase_II
k141_4932_1	1304885.AUEY01000004_gene909	1.29e-158	454.0	COG1250@1|root,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,42PBC@68525|delta/epsilon subdivisions,2WM7S@28221|Deltaproteobacteria,2MHZ4@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM 3-hydroxyacyl-CoA dehydrogenase domain protein	-	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
k141_4932_2	1304885.AUEY01000104_gene2544	1.5e-120	351.0	COG1024@1|root,COG1024@2|Bacteria,1R56Y@1224|Proteobacteria,42MRW@68525|delta/epsilon subdivisions,2WKNI@28221|Deltaproteobacteria,2MJAI@213118|Desulfobacterales	28221|Deltaproteobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
k141_4932_3	439235.Dalk_2642	2.39e-99	300.0	COG4667@1|root,COG4667@2|Bacteria,1PV7M@1224|Proteobacteria,42U1Y@68525|delta/epsilon subdivisions,2WR02@28221|Deltaproteobacteria,2MMWQ@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Patatin-like phospholipase	-	-	-	-	-	-	-	-	-	-	-	-	Patatin
k141_4932_4	96561.Dole_2590	8.04e-36	135.0	COG3884@1|root,COG3884@2|Bacteria,1RK7J@1224|Proteobacteria,42SWW@68525|delta/epsilon subdivisions,2WPK8@28221|Deltaproteobacteria,2MK3P@213118|Desulfobacterales	28221|Deltaproteobacteria	I	Acyl-ACP thioesterase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-ACP_TE
k141_252_1	377629.TERTU_4494	1.8e-44	147.0	COG4551@1|root,COG4551@2|Bacteria,1N05F@1224|Proteobacteria,1SA1I@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Belongs to the low molecular weight phosphotyrosine protein phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	LMWPc
k141_4630_2	1304885.AUEY01000001_gene3153	2.09e-107	323.0	COG0142@1|root,COG0142@2|Bacteria,1MUK6@1224|Proteobacteria,42M1B@68525|delta/epsilon subdivisions,2WK2M@28221|Deltaproteobacteria,2MJ27@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Belongs to the FPP GGPP synthase family	ispB	-	2.5.1.1,2.5.1.10,2.5.1.29,2.5.1.90	ko:K02523,ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00366	R01658,R02003,R02061,R09248	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
k141_4630_3	1121405.dsmv_1910	1.43e-78	251.0	COG0621@1|root,COG0621@2|Bacteria,1MU7N@1224|Proteobacteria,42MRJ@68525|delta/epsilon subdivisions,2WITA@28221|Deltaproteobacteria,2MISV@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12	rimO	-	2.8.4.4	ko:K14441	-	-	R10652	RC00003,RC03217	ko00000,ko01000,ko03009	-	-	-	Radical_SAM,TRAM,UPF0004
k141_269_1	1265505.ATUG01000002_gene1967	1.03e-57	188.0	2DBAY@1|root,2Z84S@2|Bacteria,1R7V4@1224|Proteobacteria,42MQE@68525|delta/epsilon subdivisions,2WJGC@28221|Deltaproteobacteria,2MJ24@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF1835
k141_269_2	765911.Thivi_0158	1.76e-44	149.0	COG1714@1|root,COG1714@2|Bacteria,1N1XF@1224|Proteobacteria,1SDY3@1236|Gammaproteobacteria,1WZR8@135613|Chromatiales	135613|Chromatiales	S	RDD family	-	-	-	-	-	-	-	-	-	-	-	-	RDD,zinc_ribbon_2
k141_4631_1	1121396.KB893123_gene1081	8.05e-87	259.0	COG2193@1|root,COG2193@2|Bacteria,1RCW7@1224|Proteobacteria,42RB9@68525|delta/epsilon subdivisions,2WMPE@28221|Deltaproteobacteria,2MJPY@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Ferritin-like domain	bfr	-	1.16.3.1	ko:K03594	ko00860,map00860	-	R00078	RC02758	ko00000,ko00001,ko01000	-	-	-	Ferritin
k141_3028_4	29495.EA26_00050	3.5e-142	412.0	2DBIX@1|root,2Z9HE@2|Bacteria,1NT20@1224|Proteobacteria,1RZMW@1236|Gammaproteobacteria,1XX3H@135623|Vibrionales	135623|Vibrionales	S	CRISPR-associated protein (Cas_Csy2)	-	-	-	ko:K19128	-	-	-	-	ko00000,ko02048	-	-	-	Cas_Csy2
k141_3028_5	29495.EA26_00045	4.61e-176	497.0	2DB80@1|root,2Z7PG@2|Bacteria,1MWE9@1224|Proteobacteria,1RNH1@1236|Gammaproteobacteria,1XTI9@135623|Vibrionales	135623|Vibrionales	S	CRISPR-associated protein (Cas_Csy3)	-	-	-	ko:K19129	-	-	-	-	ko00000,ko02048	-	-	-	Cas_Csy3
k141_1693_1	1288826.MSNKSG1_02936	7.48e-43	153.0	COG4067@1|root,COG4067@2|Bacteria,1N0VV@1224|Proteobacteria,1SZUE@1236|Gammaproteobacteria,467V0@72275|Alteromonadaceae	1236|Gammaproteobacteria	O	protein conserved in archaea	-	-	-	-	-	-	-	-	-	-	-	-	Zn_protease
k141_1693_2	443152.MDG893_10531	2.06e-194	558.0	COG1305@1|root,COG1305@2|Bacteria,1MVV3@1224|Proteobacteria,1RRIA@1236|Gammaproteobacteria,465H1@72275|Alteromonadaceae	1236|Gammaproteobacteria	E	7 transmembrane helices usually fused to an inactive transglutaminase	IV02_00930	-	-	-	-	-	-	-	-	-	-	-	7TM_transglut,Transglut_i_TM
k141_3029_1	109760.SPPG_08738T0	2.1e-05	49.7	2EFR3@1|root,2SKVX@2759|Eukaryota,3AA6Y@33154|Opisthokonta,3P4HB@4751|Fungi	4751|Fungi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL,Lipase_GDSL_2
k141_3030_1	349521.HCH_01102	2.53e-32	123.0	COG4603@1|root,COG4603@2|Bacteria,1MX6V@1224|Proteobacteria,1RS4S@1236|Gammaproteobacteria,1XJ4A@135619|Oceanospirillales	135619|Oceanospirillales	S	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
k141_3030_2	1348635.BBJY01000005_gene3302	6.64e-84	258.0	COG4603@1|root,COG4603@2|Bacteria,1MX6V@1224|Proteobacteria,1RS4S@1236|Gammaproteobacteria,1XWKM@135623|Vibrionales	1236|Gammaproteobacteria	S	Branched-chain amino acid transport system / permease component	IV02_22040	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
k141_3030_3	1348635.BBJY01000005_gene3301	1.56e-101	310.0	COG3845@1|root,COG3845@2|Bacteria,1NT0H@1224|Proteobacteria,1T1GV@1236|Gammaproteobacteria,1XVTA@135623|Vibrionales	1236|Gammaproteobacteria	S	ATPases associated with a variety of cellular activities	-	-	3.6.3.17	ko:K02056	-	M00221	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.2	-	-	ABC_tran
k141_1696_1	595460.RRSWK_02675	1.33e-19	92.0	COG0476@1|root,COG0476@2|Bacteria	2|Bacteria	H	Involved in molybdopterin and thiamine biosynthesis, family 2	-	-	2.7.7.80	ko:K21029	ko04122,map04122	-	R07459	RC00043	ko00000,ko00001,ko01000	-	-	-	ThiF
k141_1698_1	953739.SVEN_0627	2.05e-26	108.0	COG0395@1|root,COG0395@2|Bacteria,2GJ5X@201174|Actinobacteria	201174|Actinobacteria	G	Binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
k141_3034_2	246197.MXAN_5676	7.78e-13	75.1	COG4984@1|root,COG4984@2|Bacteria,1RB7Y@1224|Proteobacteria	1224|Proteobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF2157,DUF4401
k141_3035_1	158189.SpiBuddy_0440	1.48e-21	95.9	COG1653@1|root,COG1653@2|Bacteria	2|Bacteria	G	carbohydrate transport	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1,SBP_bac_8
k141_1700_1	1121459.AQXE01000015_gene280	1.55e-17	84.0	COG0042@1|root,COG0042@2|Bacteria,1MV5V@1224|Proteobacteria,42M3I@68525|delta/epsilon subdivisions,2WIXZ@28221|Deltaproteobacteria,2M90Q@213115|Desulfovibrionales	28221|Deltaproteobacteria	J	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	-	-	-	-	-	-	-	-	-	-	-	-	Dus
k141_1700_3	796620.VIBC2010_02975	1.09e-68	222.0	COG0697@1|root,COG0697@2|Bacteria,1QSKQ@1224|Proteobacteria,1RYG1@1236|Gammaproteobacteria,1XV0H@135623|Vibrionales	135623|Vibrionales	EG	of the drug metabolite transporter (DMT) superfamily	-	-	-	-	-	-	-	-	-	-	-	-	EamA
k141_3037_1	1121396.KB893058_gene2574	1.61e-63	204.0	COG1840@1|root,COG1840@2|Bacteria,1NQ3B@1224|Proteobacteria,42WYI@68525|delta/epsilon subdivisions,2WT9Q@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Bacterial extracellular solute-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_6
k141_3037_2	1121396.KB893058_gene2575	3.11e-105	314.0	COG1136@1|root,COG1136@2|Bacteria,1PXKV@1224|Proteobacteria,42PI6@68525|delta/epsilon subdivisions,2WJT8@28221|Deltaproteobacteria,2MIQT@213118|Desulfobacterales	28221|Deltaproteobacteria	V	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
k141_3037_3	1120998.AUFC01000008_gene1116	1.09e-108	318.0	COG0378@1|root,COG0378@2|Bacteria,1TQK4@1239|Firmicutes,248ZP@186801|Clostridia	186801|Clostridia	KO	Ni2 -binding GTPase involved in regulation of expression and maturation of urease and	ureG	-	-	ko:K03189,ko:K04652	-	-	-	-	ko00000,ko03110	-	-	-	cobW
k141_3038_1	118161.KB235922_gene5533	5.26e-55	186.0	COG2931@1|root,COG3240@1|root,COG2931@2|Bacteria,COG3240@2|Bacteria	2|Bacteria	I	lipase activity	-	-	3.4.24.40	ko:K01406,ko:K21831	ko01503,map01503	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	HemolysinCabind,Lipase_GDSL
k141_3039_1	177437.HRM2_29490	3.39e-44	165.0	COG0457@1|root,COG2304@1|root,COG0457@2|Bacteria,COG2304@2|Bacteria,1MW51@1224|Proteobacteria,42M45@68525|delta/epsilon subdivisions,2WM19@28221|Deltaproteobacteria,2MHT6@213118|Desulfobacterales	28221|Deltaproteobacteria	K	PFAM von Willebrand factor type A domain	batB	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	BatA,TPR_1,TPR_16,TPR_2,VWA,VWA_2
k141_3040_1	645512.GCWU000246_00461	5.78e-43	155.0	COG0803@1|root,COG0803@2|Bacteria,3TB3X@508458|Synergistetes	508458|Synergistetes	P	PFAM periplasmic solute binding protein	-	-	-	ko:K09815	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ZnuA
k141_3325_2	1286171.EAL2_c01440	1.12e-83	251.0	COG0250@1|root,COG0250@2|Bacteria,1TR3P@1239|Firmicutes,248XB@186801|Clostridia,25VW0@186806|Eubacteriaceae	186801|Clostridia	K	Participates in transcription elongation, termination and antitermination	nusG	-	-	ko:K02601	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KOW,NusG
k141_3325_3	478749.BRYFOR_08055	4.93e-75	226.0	COG0080@1|root,COG0080@2|Bacteria,1V1BS@1239|Firmicutes,24FSQ@186801|Clostridia	186801|Clostridia	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors	rplK	-	-	ko:K02867	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L11,Ribosomal_L11_N
k141_3325_4	1408823.AXUS01000015_gene1424	7.92e-129	370.0	COG0081@1|root,COG0081@2|Bacteria,1TPTS@1239|Firmicutes,247JB@186801|Clostridia,25QD0@186804|Peptostreptococcaceae	186801|Clostridia	J	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release	rplA	-	-	ko:K02863	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L1
k141_3325_5	1121324.CLIT_24c00770	3.67e-73	224.0	COG0244@1|root,COG0244@2|Bacteria,1V3JJ@1239|Firmicutes,24G9R@186801|Clostridia	186801|Clostridia	J	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors	rplJ	-	-	ko:K02864	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L10
k141_3325_6	1356854.N007_07710	7.82e-49	159.0	COG0222@1|root,COG0222@2|Bacteria,1V6EI@1239|Firmicutes,4HIGQ@91061|Bacilli,279YN@186823|Alicyclobacillaceae	91061|Bacilli	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation	rplL	-	-	ko:K02935	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L12,Ribosomal_L12_N
k141_3325_7	1301100.HG529434_gene6530	0.0	1959.0	COG0085@1|root,COG0085@2|Bacteria,1TP96@1239|Firmicutes,247J1@186801|Clostridia,36EKQ@31979|Clostridiaceae	186801|Clostridia	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	-	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
k141_3325_8	1219626.HMPREF1639_02175	0.0	1833.0	COG0086@1|root,COG0086@2|Bacteria,1TNYT@1239|Firmicutes,24925@186801|Clostridia,25QQ9@186804|Peptostreptococcaceae	186801|Clostridia	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	-	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
k141_3325_9	536232.CLM_3954	1.69e-20	84.3	COG1358@1|root,COG1358@2|Bacteria,1VFD8@1239|Firmicutes,24R27@186801|Clostridia,36MMW@31979|Clostridiaceae	186801|Clostridia	J	ribosomal protein	-	-	-	ko:K07590	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L7Ae
k141_3325_10	1121324.CLIT_24c00720	2.19e-79	237.0	COG0048@1|root,COG0048@2|Bacteria,1V1FJ@1239|Firmicutes,24FQT@186801|Clostridia	186801|Clostridia	J	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit	rpsL	-	-	ko:K02950	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosom_S12_S23
k141_3325_11	1121289.JHVL01000060_gene2529	5.7e-83	248.0	COG0049@1|root,COG0049@2|Bacteria,1V1GG@1239|Firmicutes,24FQN@186801|Clostridia,36DC5@31979|Clostridiaceae	186801|Clostridia	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA	rpsG	-	-	ko:K02992	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S7
k141_3325_12	1121324.CLIT_24c00700	0.0	1160.0	COG0480@1|root,COG0480@2|Bacteria,1TPF9@1239|Firmicutes,247VN@186801|Clostridia,25QN5@186804|Peptostreptococcaceae	186801|Clostridia	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
k141_3041_1	398578.Daci_5511	5.96e-100	364.0	COG1361@1|root,COG1361@2|Bacteria,1R00J@1224|Proteobacteria	1224|Proteobacteria	M	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_3327_2	760154.Sulba_0214	5.5e-153	435.0	COG1237@1|root,COG1237@2|Bacteria,1NK2I@1224|Proteobacteria,42RYT@68525|delta/epsilon subdivisions,2YPCW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Metal-dependent hydrolase of the beta-lactamase superfamily	-	-	2.5.1.105	ko:K06897	ko00790,map00790	-	R10339	RC00121	ko00000,ko00001,ko01000	-	-	-	Lactamase_B,Lactamase_B_2
k141_3328_1	1232437.KL661988_gene130	2.1e-26	103.0	COG0314@1|root,COG0314@2|Bacteria,1N0DM@1224|Proteobacteria,42U56@68525|delta/epsilon subdivisions,2WQRU@28221|Deltaproteobacteria,2MKRD@213118|Desulfobacterales	28221|Deltaproteobacteria	H	MoaE protein	-	-	2.8.1.12	ko:K03635	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09395	RC02507	ko00000,ko00001,ko01000	-	-	-	MoaE
k141_3328_2	1123230.ARQJ01000024_gene798	1.16e-45	154.0	COG0315@1|root,COG0315@2|Bacteria,1V3J4@1239|Firmicutes,4HH39@91061|Bacilli,4GYY0@90964|Staphylococcaceae	91061|Bacilli	H	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)	moaC	-	4.6.1.17	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R11372	RC03425	ko00000,ko00001,ko01000	-	-	-	MoaC
k141_3328_5	192952.MM_2005	7.69e-13	72.4	COG0226@1|root,arCOG00213@2157|Archaea,2XU6M@28890|Euryarchaeota,2N9KU@224756|Methanomicrobia	224756|Methanomicrobia	P	PBP superfamily domain	pstS	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
k141_3329_1	1485543.JMME01000002_gene1558	9.05e-23	99.8	COG1122@1|root,COG1122@2|Bacteria,1TPH8@1239|Firmicutes,4H21J@909932|Negativicutes	909932|Negativicutes	P	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates	ecfA	-	-	ko:K16786	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ABC_tran
k141_3043_1	314292.VAS14_05188	1.89e-51	168.0	2AW6Y@1|root,31N1Z@2|Bacteria,1QJTN@1224|Proteobacteria,1THV0@1236|Gammaproteobacteria,1XXN0@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	RDD
k141_3043_3	29495.EA26_16115	6.15e-146	415.0	COG0084@1|root,COG0084@2|Bacteria,1MUC0@1224|Proteobacteria,1RP6E@1236|Gammaproteobacteria,1XTHX@135623|Vibrionales	135623|Vibrionales	L	COG0084 Mg-dependent DNase	ycfH	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
k141_3043_4	675813.VIB_001608	4.28e-98	299.0	COG0470@1|root,COG0470@2|Bacteria,1MY1W@1224|Proteobacteria,1RNYA@1236|Gammaproteobacteria,1XU24@135623|Vibrionales	135623|Vibrionales	L	dna polymerase iii	holB	-	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNApol3-delta_C
k141_3043_5	1348635.BBJY01000007_gene99	4.3e-107	313.0	COG0125@1|root,COG0125@2|Bacteria,1MV9C@1224|Proteobacteria,1S26C@1236|Gammaproteobacteria,1XTND@135623|Vibrionales	135623|Vibrionales	F	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	tmk	GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylate_kin
k141_3043_6	1280001.BAOA01000086_gene3558	6.18e-106	316.0	COG1559@1|root,COG1559@2|Bacteria,1MUQF@1224|Proteobacteria,1RMWD@1236|Gammaproteobacteria,1XTTP@135623|Vibrionales	135623|Vibrionales	S	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation	mltG	-	-	ko:K07082	-	-	-	-	ko00000	-	-	-	YceG
k141_3330_1	177437.HRM2_39420	2.04e-63	233.0	COG0745@1|root,COG2202@1|root,COG4191@1|root,COG4936@1|root,COG0745@2|Bacteria,COG2202@2|Bacteria,COG4191@2|Bacteria,COG4936@2|Bacteria,1RCM9@1224|Proteobacteria,42M1R@68525|delta/epsilon subdivisions,2WK3J@28221|Deltaproteobacteria,2MPRS@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
k141_3331_1	641491.DND132_1374	1.11e-32	125.0	2AFUA@1|root,315WQ@2|Bacteria,1NHGB@1224|Proteobacteria,42TSA@68525|delta/epsilon subdivisions,2WQKD@28221|Deltaproteobacteria,2M9ZQ@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Putative transmembrane protein (Alph_Pro_TM)	-	-	-	-	-	-	-	-	-	-	-	-	Alph_Pro_TM
k141_3331_2	941449.dsx2_1628	6.28e-219	647.0	COG0574@1|root,COG3848@1|root,COG0574@2|Bacteria,COG3848@2|Bacteria,1QFX3@1224|Proteobacteria,42PIP@68525|delta/epsilon subdivisions,2WKWI@28221|Deltaproteobacteria,2MG9J@213115|Desulfovibrionales	28221|Deltaproteobacteria	G	PFAM Pyruvate phosphate dikinase, PEP pyruvate-binding	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PPDK_N
k141_3044_1	642227.HA49_13380	1.63e-23	99.8	COG1199@1|root,COG1199@2|Bacteria,1MVCU@1224|Proteobacteria,1RMNX@1236|Gammaproteobacteria,4BUNP@82986|Tatumella	1236|Gammaproteobacteria	KL	HELICc2	yoaA	GO:0003674,GO:0003824,GO:0004386,GO:0006139,GO:0006259,GO:0006281,GO:0006301,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008026,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0070035,GO:0071704,GO:0090304,GO:1901360	3.6.4.12	ko:K03722	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DEAD_2,Helicase_C_2,ResIII
k141_3044_2	575788.VS_2227	1.51e-16	73.6	2B7ZD@1|root,3216R@2|Bacteria,1QK8H@1224|Proteobacteria,1TIBZ@1236|Gammaproteobacteria,1XYUD@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_3044_3	945550.VISI1226_21274	2.47e-169	476.0	COG0788@1|root,COG0788@2|Bacteria,1MVCF@1224|Proteobacteria,1RN6Q@1236|Gammaproteobacteria,1XSK8@135623|Vibrionales	135623|Vibrionales	F	Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)	purU	-	3.5.1.10	ko:K01433	ko00630,ko00670,map00630,map00670	-	R00944	RC00026,RC00111	ko00000,ko00001,ko01000	-	-	-	ACT,Formyl_trans_N
k141_3044_4	1051646.VITU9109_00927	2.82e-275	772.0	COG0616@1|root,COG0616@2|Bacteria,1MUXE@1224|Proteobacteria,1RNYW@1236|Gammaproteobacteria,1XT9K@135623|Vibrionales	135623|Vibrionales	OU	signal peptide peptidase	sppA	-	-	ko:K04773	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S49
k141_3044_5	1517681.HW45_21680	4.93e-222	614.0	COG0252@1|root,COG0252@2|Bacteria,1MWIR@1224|Proteobacteria,1RMUB@1236|Gammaproteobacteria,1XU6G@135623|Vibrionales	135623|Vibrionales	EJ	COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D	ansA	-	3.5.1.1	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	-	R00485	RC00010,RC02798	ko00000,ko00001,ko01000	-	-	-	Asparaginase
k141_3044_6	675815.VOA_002342	8.4e-97	292.0	2CF8J@1|root,2Z7JD@2|Bacteria,1MYC8@1224|Proteobacteria,1RPF0@1236|Gammaproteobacteria,1XTQQ@135623|Vibrionales	135623|Vibrionales	S	Protein of unknown function (DUF2989)	VC1997	-	-	-	-	-	-	-	-	-	-	-	DUF2989
k141_3044_7	1219065.VPR01S_02_02050	6.83e-68	207.0	COG0229@1|root,COG0229@2|Bacteria,1RGWC@1224|Proteobacteria,1S5WI@1236|Gammaproteobacteria,1XXFA@135623|Vibrionales	135623|Vibrionales	C	Belongs to the MsrB Met sulfoxide reductase family	msrB	-	1.8.4.12	ko:K07305	-	-	-	-	ko00000,ko01000	-	-	-	SelR
k141_3332_1	879212.DespoDRAFT_00335	8.34e-77	244.0	COG0582@1|root,COG3585@1|root,COG0582@2|Bacteria,COG3585@2|Bacteria,1N68Q@1224|Proteobacteria,42PMW@68525|delta/epsilon subdivisions,2WKG3@28221|Deltaproteobacteria,2MJFF@213118|Desulfobacterales	28221|Deltaproteobacteria	HL	TOBE domain	-	-	-	ko:K02019	-	-	-	-	ko00000,ko03000	-	-	-	Phage_integrase,TOBE
k141_3045_1	1149133.ppKF707_2888	2.6e-16	79.3	COG0840@1|root,COG0840@2|Bacteria,1NJXF@1224|Proteobacteria,1RQXQ@1236|Gammaproteobacteria,1YEVV@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	tar	-	-	ko:K03406,ko:K05875	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal
k141_3045_2	1121918.ARWE01000001_gene433	3.45e-47	167.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42MBK@68525|delta/epsilon subdivisions,2WKDV@28221|Deltaproteobacteria,43T5B@69541|Desulfuromonadales	28221|Deltaproteobacteria	NT	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	mcp40H-17	-	-	-	-	-	-	-	-	-	-	-	CHASE3,HAMP,MCPsignal
k141_3045_3	765913.ThidrDRAFT_2452	4.32e-19	84.0	2C3ZE@1|root,32TE1@2|Bacteria,1MZNB@1224|Proteobacteria,1S924@1236|Gammaproteobacteria,1X15V@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_5427_1	1304885.AUEY01000036_gene2265	4.64e-21	93.2	COG0443@1|root,COG0443@2|Bacteria,1MXX7@1224|Proteobacteria,42NWU@68525|delta/epsilon subdivisions,2WKQQ@28221|Deltaproteobacteria,2MIBJ@213118|Desulfobacterales	28221|Deltaproteobacteria	O	Belongs to the heat shock protein 70 family	dnaK4	-	-	-	-	-	-	-	-	-	-	-	HSP70
k141_5427_2	1304885.AUEY01000036_gene2266	2.25e-173	516.0	COG0443@1|root,COG0443@2|Bacteria,1MXX7@1224|Proteobacteria,42NF1@68525|delta/epsilon subdivisions,2WK52@28221|Deltaproteobacteria,2MI9T@213118|Desulfobacterales	28221|Deltaproteobacteria	O	Belongs to the heat shock protein 70 family	-	-	-	-	-	-	-	-	-	-	-	-	DUF3731,HSP70
k141_5428_1	1304885.AUEY01000030_gene2444	8.55e-42	143.0	COG0589@1|root,COG0589@2|Bacteria,1N1GR@1224|Proteobacteria,42UJ2@68525|delta/epsilon subdivisions,2WQ5G@28221|Deltaproteobacteria,2MKK5@213118|Desulfobacterales	28221|Deltaproteobacteria	T	response to stress	-	-	-	-	-	-	-	-	-	-	-	-	Usp
k141_5428_2	1121413.JMKT01000014_gene2604	1.08e-13	71.6	COG0515@1|root,COG0515@2|Bacteria,1MVPF@1224|Proteobacteria,42PCV@68525|delta/epsilon subdivisions,2WJHA@28221|Deltaproteobacteria,2M8MX@213115|Desulfovibrionales	28221|Deltaproteobacteria	KLT	serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_5429_2	1280001.BAOA01000020_gene363	2.81e-57	183.0	COG4659@1|root,COG4659@2|Bacteria,1RDEP@1224|Proteobacteria,1RPAD@1236|Gammaproteobacteria,1XU3Z@135623|Vibrionales	135623|Vibrionales	C	Part of a membrane complex involved in electron transport	rnfG	GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0055114	-	ko:K03612	-	-	-	-	ko00000	-	-	-	FMN_bind
k141_5430_1	879212.DespoDRAFT_01300	5.01e-80	246.0	COG1028@1|root,COG1028@2|Bacteria,1PGXW@1224|Proteobacteria,42Z2I@68525|delta/epsilon subdivisions,2WUEH@28221|Deltaproteobacteria,2MNN9@213118|Desulfobacterales	28221|Deltaproteobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
k141_5431_2	29495.EA26_06915	5.98e-251	697.0	COG1760@1|root,COG1760@2|Bacteria,1MUZN@1224|Proteobacteria,1RMJZ@1236|Gammaproteobacteria,1XSZW@135623|Vibrionales	135623|Vibrionales	E	COG1760 L-serine deaminase	sdaA	-	4.3.1.17	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	-	R00220,R00590	RC00331,RC02600	ko00000,ko00001,ko01000	-	-	-	SDH_alpha,SDH_beta
k141_5431_3	223926.28806366	1.09e-151	442.0	COG2206@1|root,COG2206@2|Bacteria,1MW7F@1224|Proteobacteria,1RPEZ@1236|Gammaproteobacteria,1XVS0@135623|Vibrionales	135623|Vibrionales	T	HD-GYP domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF3391,HD,HD_5
k141_5432_1	1348635.BBJY01000042_gene25	8.88e-37	124.0	2DMNG@1|root,32SP1@2|Bacteria,1NAN7@1224|Proteobacteria,1SCJK@1236|Gammaproteobacteria,1XYIM@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_5433_1	870967.VIS19158_14149	3.36e-177	499.0	COG1161@1|root,COG1161@2|Bacteria,1MV5H@1224|Proteobacteria,1RP79@1236|Gammaproteobacteria,1XSKP@135623|Vibrionales	135623|Vibrionales	S	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity	rbgA	-	-	ko:K14540	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1
k141_5433_2	870967.VIS19158_14144	4.62e-180	508.0	COG0523@1|root,COG0523@2|Bacteria,1MVZV@1224|Proteobacteria,1RPKP@1236|Gammaproteobacteria,1XSPY@135623|Vibrionales	135623|Vibrionales	S	GTPases (G3E family)	-	-	-	-	-	-	-	-	-	-	-	-	cobW
k141_5433_3	1136163.M565_ctg5P0789	2.44e-263	730.0	COG0038@1|root,COG0038@2|Bacteria,1MV4K@1224|Proteobacteria,1RQJW@1236|Gammaproteobacteria,1XT8H@135623|Vibrionales	135623|Vibrionales	P	Probably acts as an electrical shunt for an outwardly- directed proton pump that is linked to amino acid decarboxylation, as part of the extreme acid resistance (XAR) response	clcA	-	-	ko:K03281	-	-	-	-	ko00000	2.A.49	-	-	Voltage_CLC
k141_5433_5	1116375.VEJY3_18781	9.19e-127	375.0	COG4148@1|root,COG4148@2|Bacteria,1MU8K@1224|Proteobacteria,1RQCV@1236|Gammaproteobacteria,1XZZP@135623|Vibrionales	135623|Vibrionales	P	TOBE domain	-	-	3.6.3.29	ko:K02017	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.8	-	-	ABC_tran,TOBE
k141_5433_6	1348635.BBJY01000001_gene2426	1.23e-120	348.0	COG4149@1|root,COG4149@2|Bacteria,1MUXR@1224|Proteobacteria,1RRDV@1236|Gammaproteobacteria,1Y0IC@135623|Vibrionales	135623|Vibrionales	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02018	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	-	BPD_transp_1
k141_5433_7	375286.mma_3658	5.71e-66	212.0	COG0725@1|root,COG0725@2|Bacteria,1MVNA@1224|Proteobacteria,2VJEC@28216|Betaproteobacteria,473Y2@75682|Oxalobacteraceae	28216|Betaproteobacteria	P	Bacterial extracellular solute-binding protein	modA	-	-	ko:K02020	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	-	SBP_bac_11
k141_5433_8	243277.VC_A0522	1.93e-140	434.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1R81Y@1224|Proteobacteria,1RYQ2@1236|Gammaproteobacteria,1XSR3@135623|Vibrionales	135623|Vibrionales	T	COG0642 Signal transduction histidine kinase	cqsS	GO:0000155,GO:0000156,GO:0000160,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0035556,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0060089,GO:0065007,GO:0071704,GO:0140096,GO:1901564	2.7.13.3	ko:K10916	ko02020,ko02024,ko05111,map02020,map02024,map05111	M00513	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,Response_reg
k141_5433_9	55601.VANGNB10_cII0268	2.09e-211	639.0	COG0419@1|root,COG0419@2|Bacteria,1MVTQ@1224|Proteobacteria,1RQFM@1236|Gammaproteobacteria,1XT7J@135623|Vibrionales	135623|Vibrionales	L	COG0419 ATPase involved in DNA repair	sbcC	GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0006139,GO:0006259,GO:0006260,GO:0006310,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360,GO:1901576	-	ko:K03546	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,AAA_29,SbcCD_C
k141_5433_10	675813.VIB_002277	5.57e-163	468.0	COG0420@1|root,COG0420@2|Bacteria,1MVV6@1224|Proteobacteria,1RP83@1236|Gammaproteobacteria,1XW3R@135623|Vibrionales	135623|Vibrionales	L	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity	sbcD	-	-	ko:K03547	-	-	-	-	ko00000,ko03400	-	-	-	Metallophos,SbcD_C
k141_5433_11	1348635.BBJY01000006_gene327	2.89e-175	496.0	COG1609@1|root,COG1609@2|Bacteria,1MXQ1@1224|Proteobacteria,1RNR1@1236|Gammaproteobacteria,1XT6Y@135623|Vibrionales	135623|Vibrionales	K	COG1609 Transcriptional regulators	fruR	-	-	ko:K03435	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_1,Peripla_BP_4
k141_5434_1	293826.Amet_3673	9.49e-43	148.0	2AFD1@1|root,315CT@2|Bacteria,1V3KJ@1239|Firmicutes,24I0E@186801|Clostridia,36J9P@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_5434_2	1410661.JNKW01000001_gene743	6.37e-141	418.0	COG0144@1|root,COG3270@1|root,COG0144@2|Bacteria,COG3270@2|Bacteria,1TPGQ@1239|Firmicutes,247N0@186801|Clostridia	186801|Clostridia	J	NOL1 NOP2 sun family	rsmF	-	-	-	-	-	-	-	-	-	-	-	Methyltr_RsmB-F,Methyltr_RsmF_N,Methyltranf_PUA,RsmF_methylt_CI
k141_1122_1	457398.HMPREF0326_01825	9.11e-46	161.0	COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,42MK4@68525|delta/epsilon subdivisions,2WJJ8@28221|Deltaproteobacteria,2M81W@213115|Desulfovibrionales	28221|Deltaproteobacteria	G	PFAM TRAP C4-dicarboxylate transport system permease DctM subunit	-	-	-	-	-	-	-	-	-	-	-	-	DctM
k141_1459_1	1224318.DT73_04280	3.65e-181	539.0	COG0834@1|root,COG2206@1|root,COG3437@1|root,COG0834@2|Bacteria,COG2206@2|Bacteria,COG3437@2|Bacteria,1MV37@1224|Proteobacteria,1RM9C@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	COG0840 Methyl-accepting chemotaxis protein	-	-	-	-	-	-	-	-	-	-	-	-	HD_5,SBP_bac_3,dCache_1
k141_1797_1	293826.Amet_1274	2.1e-124	389.0	COG2203@1|root,COG3437@1|root,COG2203@2|Bacteria,COG3437@2|Bacteria,1UQJH@1239|Firmicutes,248UM@186801|Clostridia,36DPS@31979|Clostridiaceae	186801|Clostridia	T	domain protein	rpfG3	-	-	ko:K07814	-	-	-	-	ko00000,ko02022	-	-	-	GAF_2,GGDEF,HD,HD_5,PAS_3,Response_reg
k141_1797_2	755731.Clo1100_2287	1.23e-113	331.0	COG0745@1|root,COG0745@2|Bacteria,1TP9M@1239|Firmicutes,247TK@186801|Clostridia,36DZG@31979|Clostridiaceae	186801|Clostridia	T	response regulator, receiver	phoP_1	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
k141_1797_3	1415774.U728_324	2.18e-74	263.0	COG0642@1|root,COG2205@2|Bacteria,1TP73@1239|Firmicutes,248Y6@186801|Clostridia,36ERK@31979|Clostridiaceae	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
k141_1797_4	999411.HMPREF1092_03035	1.12e-81	253.0	COG1120@1|root,COG1120@2|Bacteria,1TP2Q@1239|Firmicutes,2492Z@186801|Clostridia,36EEP@31979|Clostridiaceae	186801|Clostridia	HP	ABC transporter	-	-	3.6.3.34	ko:K02013	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	ABC_tran
k141_1797_5	332101.JIBU02000018_gene2328	6.26e-104	315.0	COG0609@1|root,COG0609@2|Bacteria,1TPX6@1239|Firmicutes,248IS@186801|Clostridia,36EB1@31979|Clostridiaceae	186801|Clostridia	P	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily	-	-	-	ko:K02015	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	FecCD
k141_1797_6	1292035.H476_0768	2.58e-80	254.0	COG0614@1|root,COG0614@2|Bacteria,1TSAF@1239|Firmicutes,24ITQ@186801|Clostridia,25SE3@186804|Peptostreptococcaceae	186801|Clostridia	P	Periplasmic binding protein	-	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
k141_1797_7	1151292.QEW_4267	2.58e-64	229.0	COG0584@1|root,COG4781@1|root,COG0584@2|Bacteria,COG4781@2|Bacteria,1UGF1@1239|Firmicutes,25E4R@186801|Clostridia,25TP7@186804|Peptostreptococcaceae	186801|Clostridia	C	Membrane domain of glycerophosphoryl diester phosphodiesterase	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD,GPDPase_memb
k141_1797_8	469381.Dpep_0470	1.01e-102	318.0	COG0477@1|root,COG2814@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
k141_1797_9	1256908.HMPREF0373_03059	1.6e-43	144.0	COG0393@1|root,COG0393@2|Bacteria,1VADM@1239|Firmicutes,24J8R@186801|Clostridia,25WII@186806|Eubacteriaceae	186801|Clostridia	S	Belongs to the UPF0145 family	-	-	-	-	-	-	-	-	-	-	-	-	YbjQ_1
k141_1797_10	1385514.N782_05670	2.45e-116	337.0	COG3153@1|root,COG3153@2|Bacteria,1V3PW@1239|Firmicutes,4HGZK@91061|Bacilli,2YBRN@289201|Pontibacillus	91061|Bacilli	S	Acetyltransferase (GNAT) domain	-	-	-	ko:K03824	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_1,Acetyltransf_9
k141_1797_11	572544.Ilyop_0956	4.42e-116	336.0	COG0655@1|root,COG0655@2|Bacteria,37A1W@32066|Fusobacteria	32066|Fusobacteria	S	NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
k141_1797_12	1487921.DP68_13015	2.98e-88	262.0	COG0778@1|root,COG0778@2|Bacteria,1V4DP@1239|Firmicutes,24HBZ@186801|Clostridia,36I36@31979|Clostridiaceae	186801|Clostridia	C	nitroreductase	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
k141_1797_13	425104.Ssed_2097	4.75e-35	135.0	COG2207@1|root,COG2207@2|Bacteria,1RB3B@1224|Proteobacteria,1S2BJ@1236|Gammaproteobacteria,2QB7A@267890|Shewanellaceae	1236|Gammaproteobacteria	K	PFAM helix-turn-helix- domain containing protein, AraC type	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
k141_1797_14	572544.Ilyop_1601	4.02e-26	104.0	COG1149@1|root,COG1149@2|Bacteria	2|Bacteria	C	4 iron, 4 sulfur cluster binding	ldpA	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_6,LdpA_C
k141_1797_15	903814.ELI_1732	1.56e-79	246.0	COG1126@1|root,COG1126@2|Bacteria,1UZPS@1239|Firmicutes,249JK@186801|Clostridia	186801|Clostridia	E	ATPases associated with a variety of cellular activities	-	-	3.6.3.21	ko:K02028	-	M00236	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.3	-	-	ABC_tran
k141_1797_16	290402.Cbei_2511	1.87e-14	77.8	COG0765@1|root,COG0765@2|Bacteria,1TR7R@1239|Firmicutes,24823@186801|Clostridia,36DWH@31979|Clostridiaceae	186801|Clostridia	P	amino acid ABC transporter	-	-	-	ko:K02029	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	BPD_transp_1
k141_1797_17	903814.ELI_1730	3.01e-66	214.0	COG0834@1|root,COG0834@2|Bacteria,1V0E4@1239|Firmicutes,24CJC@186801|Clostridia,25X49@186806|Eubacteriaceae	186801|Clostridia	ET	Ligated ion channel L-glutamate- and glycine-binding site	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
k141_1797_18	1121324.CLIT_10c04330	6.54e-218	615.0	COG2897@1|root,COG2897@2|Bacteria,1TS7E@1239|Firmicutes,24CNW@186801|Clostridia,25SF2@186804|Peptostreptococcaceae	186801|Clostridia	P	Rhodanese Homology Domain	-	-	2.8.1.1,2.8.1.11,2.8.1.2	ko:K01011,ko:K21028	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106,R07461	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
k141_1797_19	1232447.BAHW02000027_gene1915	3.66e-107	314.0	COG0740@1|root,COG0740@2|Bacteria,1TQ91@1239|Firmicutes,247QY@186801|Clostridia,267WQ@186813|unclassified Clostridiales	186801|Clostridia	OU	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
k141_1797_20	445971.ANASTE_01776	9.71e-38	140.0	COG2768@1|root,COG2768@2|Bacteria,1V2K1@1239|Firmicutes,24FX2@186801|Clostridia,25VW2@186806|Eubacteriaceae	186801|Clostridia	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_4,Fer4_9
k141_1797_21	1235798.C817_01434	2.04e-42	144.0	COG2207@1|root,COG2207@2|Bacteria,1V9Y0@1239|Firmicutes,24N56@186801|Clostridia	186801|Clostridia	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
k141_1797_24	1216932.CM240_0062	2.16e-148	428.0	COG0133@1|root,COG0133@2|Bacteria,1TPI3@1239|Firmicutes,24881@186801|Clostridia,36E14@31979|Clostridiaceae	186801|Clostridia	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB	-	4.2.1.20	ko:K01696,ko:K06001	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
k141_1797_25	1121405.dsmv_2608	7.61e-08	62.8	COG0498@1|root,COG0498@2|Bacteria	2|Bacteria	E	threonine synthase activity	-	-	2.5.1.76,4.2.3.1	ko:K01733,ko:K15527	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetyltransf_1,PALP
k141_1797_26	1123371.ATXH01000002_gene303	2.36e-108	383.0	COG1506@1|root,COG4625@1|root,COG1506@2|Bacteria,COG4625@2|Bacteria	2|Bacteria	T	pathogenesis	pip	-	4.2.2.23	ko:K06972,ko:K18195	-	-	-	-	ko00000,ko01000,ko01002	-	PL4	-	Abhydrolase_1,Autotransporter,DUF285,Peptidase_S9
k141_1123_1	999550.KI421507_gene951	2.38e-58	187.0	COG2391@1|root,COG2391@2|Bacteria,1R5DN@1224|Proteobacteria,2U2XY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	YeeE YedE family protein	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
k141_1123_2	1168067.JAGP01000001_gene1493	1.67e-09	58.2	COG2391@1|root,COG2391@2|Bacteria,1RIWE@1224|Proteobacteria,1SE17@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Sulphur transport	-	-	-	-	-	-	-	-	-	-	-	-	Sulf_transp
k141_2115_2	1304885.AUEY01000091_gene1631	6.7e-148	438.0	COG2925@1|root,COG2925@2|Bacteria,1MV0U@1224|Proteobacteria,42Q6Y@68525|delta/epsilon subdivisions,2WJK0@28221|Deltaproteobacteria,2MI1Y@213118|Desulfobacterales	28221|Deltaproteobacteria	L	Exonuclease C-terminal	-	-	3.1.11.1	ko:K01141	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_X-T_C,RNase_T
k141_2115_3	1122603.ATVI01000008_gene2213	1.15e-63	204.0	COG1305@1|root,COG1305@2|Bacteria,1R9XR@1224|Proteobacteria,1S4S3@1236|Gammaproteobacteria,1X66X@135614|Xanthomonadales	135614|Xanthomonadales	E	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
k141_3827_1	198628.Dda3937_00824	3.56e-182	531.0	COG3209@1|root,COG3209@2|Bacteria,1NU4C@1224|Proteobacteria,1SMEW@1236|Gammaproteobacteria,2JEMU@204037|Dickeya	1236|Gammaproteobacteria	M	RHS protein	-	-	-	-	-	-	-	-	-	-	-	-	RHS,RHS_repeat
k141_3827_4	1082705.JIBP01000004_gene1358	1.67e-119	368.0	COG3209@1|root,COG3209@2|Bacteria,1NQ44@1224|Proteobacteria,1SK6W@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	RHS Repeat	-	-	-	-	-	-	-	-	-	-	-	-	RHS,RHS_repeat
k141_1124_1	667014.Thein_0797	2.76e-27	112.0	COG3637@1|root,COG3637@2|Bacteria	2|Bacteria	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	Porin_O_P
k141_1798_1	879212.DespoDRAFT_02626	1.55e-10	59.7	29GM5@1|root,303IT@2|Bacteria,1RG3T@1224|Proteobacteria,42RUX@68525|delta/epsilon subdivisions,2WNMJ@28221|Deltaproteobacteria,2MJY1@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4390)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4390
k141_1798_2	177437.HRM2_11170	4.46e-26	110.0	COG5000@1|root,COG5000@2|Bacteria,1MWKZ@1224|Proteobacteria,42MCN@68525|delta/epsilon subdivisions,2WIYA@28221|Deltaproteobacteria,2MHZN@213118|Desulfobacterales	28221|Deltaproteobacteria	T	histidine kinase HAMP region domain protein	ntrY	-	2.7.13.3	ko:K13598	ko02020,map02020	M00498	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4
k141_1798_3	338963.Pcar_2344	1.82e-16	80.5	COG5000@1|root,COG5000@2|Bacteria,1MWKZ@1224|Proteobacteria,42MCN@68525|delta/epsilon subdivisions,2WIYA@28221|Deltaproteobacteria,43SDF@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	PAS domain	ntrY	-	2.7.13.3	ko:K13598	ko02020,map02020	M00498	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4
k141_4867_1	159087.Daro_2427	4.82e-31	122.0	COG1835@1|root,COG1835@2|Bacteria,1RF4N@1224|Proteobacteria,2W48X@28216|Betaproteobacteria	28216|Betaproteobacteria	I	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
k141_4867_2	857087.Metme_1342	3.94e-116	349.0	COG0438@1|root,COG0438@2|Bacteria,1MU9C@1224|Proteobacteria,1RYBJ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
k141_4867_3	1276756.AUEX01000004_gene2487	2.67e-111	336.0	COG0438@1|root,COG0438@2|Bacteria,1R564@1224|Proteobacteria,2WEG5@28216|Betaproteobacteria,4ABFC@80864|Comamonadaceae	28216|Betaproteobacteria	M	Glycosyl transferase 4-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
k141_4542_1	1158604.I591_01709	7.44e-74	242.0	COG2113@1|root,COG4176@1|root,COG2113@2|Bacteria,COG4176@2|Bacteria,1TP82@1239|Firmicutes,4H9MM@91061|Bacilli,4B031@81852|Enterococcaceae	91061|Bacilli	E	Substrate binding domain of ABC-type glycine betaine transport system	busAB	-	-	ko:K02001,ko:K02002	ko02010,map02010	M00208	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	BPD_transp_1,OpuAC
k141_4542_2	485915.Dret_1273	8.61e-88	271.0	COG0583@1|root,COG0583@2|Bacteria,1PR6U@1224|Proteobacteria,42QAK@68525|delta/epsilon subdivisions,2WM9C@28221|Deltaproteobacteria,2MBPW@213115|Desulfovibrionales	28221|Deltaproteobacteria	K	PFAM LysR substrate-binding	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
k141_4542_3	644282.Deba_3271	2.88e-50	182.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42N03@68525|delta/epsilon subdivisions,2WIX4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	NT	PFAM chemotaxis sensory transducer	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HBM,MCPsignal
k141_1125_1	647113.Metok_1236	3.72e-34	129.0	COG1418@1|root,arCOG01860@2157|Archaea,2XY6N@28890|Euryarchaeota	28890|Euryarchaeota	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	-	-	-	-	-	-	-	-	-	HD
k141_4868_1	1121405.dsmv_2186	2e-92	288.0	COG1219@1|root,COG1219@2|Bacteria,1MWIZ@1224|Proteobacteria,42N1Z@68525|delta/epsilon subdivisions,2WJUS@28221|Deltaproteobacteria,2MHMD@213118|Desulfobacterales	28221|Deltaproteobacteria	O	Belongs to the ClpX chaperone family	-	-	-	-	-	-	-	-	-	-	-	-	AAA_2,ClpB_D2-small
k141_1799_1	1243664.CAVL020000032_gene2820	1.2e-18	94.4	COG2200@1|root,COG2200@2|Bacteria,1TQ94@1239|Firmicutes,4HAY4@91061|Bacilli,1ZB7X@1386|Bacillus	91061|Bacilli	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	CBS,EAL,GGDEF
k141_3828_1	1232410.KI421413_gene705	2.37e-134	392.0	COG1702@1|root,COG1702@2|Bacteria,1MVDV@1224|Proteobacteria,42N58@68525|delta/epsilon subdivisions,2WIQS@28221|Deltaproteobacteria,43S08@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	AAA domain	phoH2	-	-	ko:K06217	-	-	-	-	ko00000	-	-	-	PhoH
k141_4869_2	666681.M301_1866	8.42e-22	93.2	COG0725@1|root,COG0725@2|Bacteria,1MVNA@1224|Proteobacteria,2VJEC@28216|Betaproteobacteria,2KKB4@206350|Nitrosomonadales	206350|Nitrosomonadales	P	TIGRFAM molybdenum ABC transporter, periplasmic molybdate-binding protein	-	-	-	ko:K02020	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	-	SBP_bac_11
k141_2779_1	1121921.KB898715_gene45	4.81e-80	302.0	COG2268@1|root,COG3210@1|root,COG2268@2|Bacteria,COG3210@2|Bacteria,1MX2K@1224|Proteobacteria,1RNRK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	U	Large exoproteins involved in heme utilization or adhesion	-	-	-	-	-	-	-	-	-	-	-	-	Fil_haemagg,Haemagg_act
k141_2779_3	675814.VIC_005078	1.92e-39	145.0	COG3210@1|root,COG3210@2|Bacteria,1MX2K@1224|Proteobacteria,1RNRK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	U	Large exoproteins involved in heme utilization or adhesion	-	-	-	ko:K15125	ko05133,map05133	-	-	-	ko00000,ko00001,ko00536	-	-	-	DUF637,Fil_haemagg_2,Haemagg_act
k141_2779_5	1121921.KB898709_gene226	1.05e-26	106.0	2EC1K@1|root,3360Q@2|Bacteria,1NCHK@1224|Proteobacteria,1SFZB@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_4152_2	243277.VC_1488	0.0	1033.0	COG0116@1|root,COG1092@1|root,COG0116@2|Bacteria,COG1092@2|Bacteria,1MUQM@1224|Proteobacteria,1RNMH@1236|Gammaproteobacteria,1XSNR@135623|Vibrionales	135623|Vibrionales	J	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA	rlmL	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0008990,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.173,2.1.1.264	ko:K12297	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM,THUMP,UPF0020
k141_4152_3	1348635.BBJY01000005_gene3246	5.73e-70	217.0	28I7M@1|root,2Z8AH@2|Bacteria,1N1DT@1224|Proteobacteria,1RYK3@1236|Gammaproteobacteria,1XVKE@135623|Vibrionales	135623|Vibrionales	D	Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ	zapC	-	-	ko:K18657	-	-	-	-	ko00000,ko03036	-	-	-	ZapC
k141_4152_4	1348635.BBJY01000005_gene3247	1.46e-218	605.0	COG0167@1|root,COG0167@2|Bacteria,1MU7C@1224|Proteobacteria,1RMCP@1236|Gammaproteobacteria,1XU4H@135623|Vibrionales	135623|Vibrionales	F	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor	pyrD	GO:0003674,GO:0003824,GO:0004152,GO:0004158,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016627,GO:0016634,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	1.3.5.2	ko:K00254	ko00240,ko01100,map00240,map01100	M00051	R01868	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
k141_4152_5	1348635.BBJY01000005_gene3248	0.0	1504.0	COG2902@1|root,COG2902@2|Bacteria,1MXNV@1224|Proteobacteria,1RQVZ@1236|Gammaproteobacteria,1XUBT@135623|Vibrionales	135623|Vibrionales	E	NAD-specific glutamate dehydrogenase	gdhB	-	1.4.1.2	ko:K15371	ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100	-	R00243	RC00006,RC02799	ko00000,ko00001,ko01000	-	-	-	Bac_GDH
k141_1800_2	1279009.ADICEAN_03539	3.01e-88	272.0	COG0389@1|root,COG0389@2|Bacteria,4NF1Y@976|Bacteroidetes,47JB9@768503|Cytophagia	976|Bacteroidetes	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	dinB	-	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
k141_499_3	1219076.N646_1745	2.16e-219	607.0	COG0078@1|root,COG0078@2|Bacteria,1MUFM@1224|Proteobacteria,1RQ59@1236|Gammaproteobacteria,1XTDM@135623|Vibrionales	135623|Vibrionales	E	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline	argF	GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.1.3.3	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844	R01398	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
k141_499_4	672.VV93_v1c26430	1.84e-192	537.0	COG0540@1|root,COG0540@2|Bacteria,1MWAB@1224|Proteobacteria,1RPSV@1236|Gammaproteobacteria,1XTYG@135623|Vibrionales	135623|Vibrionales	F	Belongs to the ATCase OTCase family	pyrB	GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
k141_499_6	55601.VANGNB10_cI2267	9.38e-81	240.0	COG0251@1|root,COG0251@2|Bacteria,1MZ3J@1224|Proteobacteria,1S5XS@1236|Gammaproteobacteria,1XWXC@135623|Vibrionales	135623|Vibrionales	J	translation initiation inhibitor, yjgF family	yjgF	-	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP
k141_499_7	1116375.VEJY3_13630	2.48e-133	382.0	COG0204@1|root,COG0204@2|Bacteria,1MY51@1224|Proteobacteria,1RQYC@1236|Gammaproteobacteria,1XTMX@135623|Vibrionales	135623|Vibrionales	I	Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family	plsC	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
k141_499_8	1517681.HW45_19425	2.6e-255	706.0	COG0766@1|root,COG0766@2|Bacteria,1MUH7@1224|Proteobacteria,1RN91@1236|Gammaproteobacteria,1XT5M@135623|Vibrionales	135623|Vibrionales	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA	GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008760,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016740,GO:0016765,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
k141_499_9	945543.VIBR0546_01034	1.05e-47	153.0	COG5007@1|root,COG5007@2|Bacteria,1N1WJ@1224|Proteobacteria,1SCAR@1236|Gammaproteobacteria,1XXSQ@135623|Vibrionales	135623|Vibrionales	K	Belongs to the BolA IbaG family	yrbA	-	-	-	-	-	-	-	-	-	-	-	BolA
k141_499_10	675815.VOA_003360	3.33e-36	125.0	COG3113@1|root,COG3113@2|Bacteria,1NGIE@1224|Proteobacteria,1SGH6@1236|Gammaproteobacteria,1XYDH@135623|Vibrionales	135623|Vibrionales	S	NTP binding protein (contains STAS domain)	yrbB	-	-	ko:K07122	ko02010,map02010	M00210	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27.3	-	-	STAS_2
k141_499_11	675816.VIA_000165	2.5e-85	258.0	COG2854@1|root,COG2854@2|Bacteria,1NKFA@1224|Proteobacteria,1RNJW@1236|Gammaproteobacteria,1XT3S@135623|Vibrionales	135623|Vibrionales	Q	ABC-type transport system involved in resistance to organic solvents, auxiliary component	mlaC	-	-	ko:K07323	ko02010,map02010	M00210	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27.3	-	-	MlaC
k141_499_13	1280001.BAOA01000048_gene1862	1.95e-159	450.0	COG0767@1|root,COG0767@2|Bacteria,1MVPN@1224|Proteobacteria,1RM9H@1236|Gammaproteobacteria,1XSVZ@135623|Vibrionales	135623|Vibrionales	Q	COG0767 ABC-type transport system involved in resistance to organic solvents, permease component	mlaE	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
k141_499_14	674977.VMC_34670	1.78e-157	445.0	COG1127@1|root,COG1127@2|Bacteria,1MUSD@1224|Proteobacteria,1RMCJ@1236|Gammaproteobacteria,1XVHP@135623|Vibrionales	135623|Vibrionales	Q	ABC-type transport system involved in resistance to organic solvents, ATPase component	mlaF	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran,BCA_ABC_TP_C
k141_499_15	1219065.VPR01S_04_00330	3.66e-175	494.0	COG0530@1|root,COG0530@2|Bacteria,1MU3R@1224|Proteobacteria,1RMRD@1236|Gammaproteobacteria,1XUQS@135623|Vibrionales	135623|Vibrionales	P	COG0530 Ca2 Na antiporter	yrbG	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
k141_499_16	675813.VIB_000604	3.64e-174	492.0	COG0517@1|root,COG0794@1|root,COG0517@2|Bacteria,COG0794@2|Bacteria,1MUXD@1224|Proteobacteria,1RMT9@1236|Gammaproteobacteria,1XTGN@135623|Vibrionales	135623|Vibrionales	M	sugar phosphate isomerase involved in capsule formation	kdsD	-	5.3.1.13	ko:K06041	ko00540,ko01100,map00540,map01100	M00063	R01530	RC00541	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CBS,SIS
k141_499_17	345073.VC395_2638	4.44e-86	257.0	COG1778@1|root,COG1778@2|Bacteria,1RH85@1224|Proteobacteria,1S6D0@1236|Gammaproteobacteria,1XSN7@135623|Vibrionales	135623|Vibrionales	S	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate	kdsC	-	3.1.3.45	ko:K03270	ko00540,ko01100,map00540,map01100	M00063	R03350	RC00017	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hydrolase_3
k141_1801_1	706587.Desti_4370	5.19e-62	205.0	COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,42MK4@68525|delta/epsilon subdivisions,2WJJ8@28221|Deltaproteobacteria,2MR9B@213462|Syntrophobacterales	28221|Deltaproteobacteria	G	transporter, DctM subunit	-	-	-	ko:K11690	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.56.1	-	-	DctM
k141_1462_1	945543.VIBR0546_06407	1.7e-83	281.0	COG1388@1|root,COG1388@2|Bacteria,1NCX4@1224|Proteobacteria,1SZR4@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	COG1388 FOG LysM repeat	-	-	-	-	-	-	-	-	-	-	-	-	LysM
k141_1462_3	1348635.BBJY01000004_gene2890	0.000319	48.9	COG3501@1|root,COG3501@2|Bacteria,1MU7Q@1224|Proteobacteria,1RMZS@1236|Gammaproteobacteria,1XUHW@135623|Vibrionales	135623|Vibrionales	M	protein conserved in bacteria	vgrG1	GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0006464,GO:0006807,GO:0006996,GO:0007010,GO:0007015,GO:0008144,GO:0008150,GO:0008152,GO:0008154,GO:0009405,GO:0009987,GO:0016043,GO:0016874,GO:0016879,GO:0016881,GO:0017076,GO:0018149,GO:0018153,GO:0018193,GO:0018199,GO:0018205,GO:0018262,GO:0018995,GO:0019538,GO:0022411,GO:0030029,GO:0030036,GO:0030042,GO:0030430,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032984,GO:0033643,GO:0033646,GO:0035639,GO:0036094,GO:0036211,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0043624,GO:0043656,GO:0043657,GO:0043933,GO:0044215,GO:0044216,GO:0044217,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044419,GO:0046872,GO:0051261,GO:0051704,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:0097435,GO:1901265,GO:1901363,GO:1901564	-	ko:K11904	ko03070,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	PG_binding_1,Phage_GPD
k141_3830_1	439235.Dalk_2654	2.17e-67	223.0	COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,42MEA@68525|delta/epsilon subdivisions,2WIW6@28221|Deltaproteobacteria,2MMMT@213118|Desulfobacterales	28221|Deltaproteobacteria	K	PFAM sigma-54 factor interaction domain-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HTH_8,Sigma54_activat
k141_3830_2	768671.ThimaDRAFT_2048	5.41e-48	163.0	COG4313@1|root,COG4313@2|Bacteria,1ND6Y@1224|Proteobacteria,1RYD3@1236|Gammaproteobacteria,1WW33@135613|Chromatiales	135613|Chromatiales	C	Putative MetA-pathway of phenol degradation	-	-	-	-	-	-	-	-	-	-	-	-	Phenol_MetA_deg
k141_4870_1	1536769.P40081_07065	4.4e-18	87.0	COG3210@1|root,COG3210@2|Bacteria	2|Bacteria	U	domain, Protein	-	-	-	ko:K15125	ko05133,map05133	-	-	-	ko00000,ko00001,ko00536	-	-	-	PT-TG,TNT,Toxin-deaminase,WXG100
k141_1802_1	1410665.JNKR01000012_gene816	1.38e-68	223.0	COG1940@1|root,COG1940@2|Bacteria,1TRT1@1239|Firmicutes,4H48A@909932|Negativicutes	909932|Negativicutes	GK	ROK family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_24,ROK
k141_1126_1	1304885.AUEY01000073_gene1470	9.52e-44	146.0	COG0727@1|root,COG0727@2|Bacteria,1N3F5@1224|Proteobacteria,42T7I@68525|delta/epsilon subdivisions,2WPNZ@28221|Deltaproteobacteria,2MK3Z@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Putative zinc- or iron-chelating domain	-	-	-	ko:K06940	-	-	-	-	ko00000	-	-	-	CxxCxxCC
k141_5161_15	1454007.JAUG01000091_gene691	3.6e-14	83.2	COG0793@1|root,COG0793@2|Bacteria,4NGGJ@976|Bacteroidetes,1ITFP@117747|Sphingobacteriia	976|Bacteroidetes	M	Peptidase family S41	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S41
k141_5161_16	392499.Swit_3481	7.89e-20	100.0	COG4928@1|root,COG4928@2|Bacteria,1MWRP@1224|Proteobacteria,2VBBP@28211|Alphaproteobacteria,2KB6V@204457|Sphingomonadales	204457|Sphingomonadales	S	KAP family P-loop domain	-	-	-	-	-	-	-	-	-	-	-	-	KAP_NTPase
k141_5161_21	1230342.CTM_06731	1.07e-187	536.0	COG0534@1|root,COG0534@2|Bacteria,1TPPJ@1239|Firmicutes,25AZE@186801|Clostridia,36ESK@31979|Clostridiaceae	186801|Clostridia	V	MatE	-	-	-	-	-	-	-	-	-	-	-	-	MatE
k141_3978_2	1121405.dsmv_3105	1e-109	319.0	COG0740@1|root,COG0740@2|Bacteria,1MV46@1224|Proteobacteria,42MFU@68525|delta/epsilon subdivisions,2WK74@28221|Deltaproteobacteria,2MJ0K@213118|Desulfobacterales	28221|Deltaproteobacteria	O	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
k141_3978_3	933262.AXAM01000023_gene645	8.88e-40	144.0	COG1219@1|root,COG1219@2|Bacteria,1MVQK@1224|Proteobacteria,42MWJ@68525|delta/epsilon subdivisions,2WJ8Q@28221|Deltaproteobacteria,2MHKY@213118|Desulfobacterales	28221|Deltaproteobacteria	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
k141_1990_1	1076550.LH22_10850	4.27e-25	107.0	2DBUF@1|root,2ZB5S@2|Bacteria,1NUFT@1224|Proteobacteria,1RYW0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	ko:K13409	ko02010,ko04626,map02010,map04626	M00339	-	-	ko00000,ko00001,ko00002,ko02000,ko02044	3.A.1.110	-	-	Asp_protease_2
k141_3678_1	643867.Ftrac_2263	7.47e-06	56.6	COG3290@1|root,COG3290@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	-	-	2.1.1.80,2.7.11.1,3.1.1.61,3.1.3.3	ko:K07315,ko:K12132,ko:K13924	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035,ko03021	-	-	-	FeS,Fe_hyd_lg_C,Fer4,Fer4_7,GGDEF,HATPase_c,HisKA_2,PAS,PAS_3,PAS_4,PAS_9,SpoIIE
k141_4970_1	1116375.VEJY3_17741	1.1e-255	719.0	COG4666@1|root,COG4666@2|Bacteria,1MUNB@1224|Proteobacteria,1RMH7@1236|Gammaproteobacteria,1XV3R@135623|Vibrionales	135623|Vibrionales	S	Tripartite ATP-independent periplasmic transporter, DctM component	-	-	-	-	-	-	-	-	-	-	-	-	DctM
k141_4970_2	1188252.AJYK01000021_gene1483	9.37e-154	439.0	COG2358@1|root,COG2358@2|Bacteria,1MXW1@1224|Proteobacteria,1RYBC@1236|Gammaproteobacteria,1XTNX@135623|Vibrionales	135623|Vibrionales	S	ABC transporter, phosphonate, periplasmic substrate-binding protein	-	-	-	ko:K07080	-	-	-	-	ko00000	-	-	-	NMT1_3
k141_626_2	203275.BFO_0133	4.6e-317	889.0	COG1882@1|root,COG1882@2|Bacteria,4NDWW@976|Bacteroidetes,2FMC2@200643|Bacteroidia,22WNW@171551|Porphyromonadaceae	976|Bacteroidetes	C	Pyruvate formate lyase-like	-	-	2.3.1.54,4.1.1.83	ko:K00656,ko:K18427	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	-	R00212,R06987	RC00004,RC01181,RC02742,RC02833	ko00000,ko00001,ko01000	-	-	-	Gly_radical,PFL-like
k141_3979_1	1499967.BAYZ01000016_gene6560	3.26e-27	113.0	COG2815@1|root,COG2815@2|Bacteria,2NPV8@2323|unclassified Bacteria	2|Bacteria	S	PASTA	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA
k141_5253_1	345073.VC395_A0552	9.27e-49	169.0	COG2425@1|root,COG2425@2|Bacteria,1N1RQ@1224|Proteobacteria,1RPQT@1236|Gammaproteobacteria,1XTJ0@135623|Vibrionales	135623|Vibrionales	S	protein containing a von Willebrand factor type A (vWA) domain	yieM	-	-	-	-	-	-	-	-	-	-	-	VWA_CoxE
k141_5253_2	1280001.BAOA01000072_gene2787	4.68e-74	239.0	COG2425@1|root,COG2425@2|Bacteria,1N1RQ@1224|Proteobacteria,1RPQT@1236|Gammaproteobacteria,1XTJ0@135623|Vibrionales	135623|Vibrionales	S	protein containing a von Willebrand factor type A (vWA) domain	yieM	-	-	-	-	-	-	-	-	-	-	-	VWA_CoxE
k141_1993_2	1348635.BBJY01000017_gene4115	1.01e-78	241.0	COG0159@1|root,COG0159@2|Bacteria,1MXJV@1224|Proteobacteria,1RMGN@1236|Gammaproteobacteria,1XTDE@135623|Vibrionales	135623|Vibrionales	E	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate	trpA	GO:0000162,GO:0003674,GO:0003824,GO:0004834,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.2.1.20	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_syntA
k141_2566_1	2325.TKV_c14420	1.48e-39	145.0	COG0044@1|root,COG0044@2|Bacteria,1TPQM@1239|Firmicutes,247V2@186801|Clostridia,42F1H@68295|Thermoanaerobacterales	186801|Clostridia	F	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily	pyrC	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
k141_2566_2	1121396.KB893057_gene2515	2.93e-84	265.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,2MI1N@213118|Desulfobacterales	28221|Deltaproteobacteria	T	sigma-54 factor interaction domain-containing protein	pilR	-	-	ko:K02667	ko02020,map02020	M00501	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	HTH_8,Response_reg,Sigma54_activat
k141_3681_1	189753.AXAS01000020_gene1670	3.24e-26	109.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2TR8X@28211|Alphaproteobacteria,3JUJN@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	2.7.13.3	ko:K10125	ko02020,map02020	M00504	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,dCache_1
k141_3681_2	159087.Daro_2923	6.94e-13	70.1	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2VHSB@28216|Betaproteobacteria,2KVV3@206389|Rhodocyclales	206389|Rhodocyclales	T	Bacterial regulatory protein, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
k141_4685_1	1304885.AUEY01000022_gene3396	5.28e-215	598.0	COG2805@1|root,COG2805@2|Bacteria,1MU3J@1224|Proteobacteria,42M7F@68525|delta/epsilon subdivisions,2WIMF@28221|Deltaproteobacteria,2MII7@213118|Desulfobacterales	28221|Deltaproteobacteria	NU	PFAM type II secretion system protein E	-	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
k141_4685_2	1304885.AUEY01000022_gene3398	5.76e-39	132.0	COG0762@1|root,COG0762@2|Bacteria,1QDB9@1224|Proteobacteria,42VCU@68525|delta/epsilon subdivisions,2WRHX@28221|Deltaproteobacteria,2MKPA@213118|Desulfobacterales	28221|Deltaproteobacteria	S	YGGT family	-	-	-	ko:K02221	-	-	-	-	ko00000,ko02044	-	-	-	YGGT
k141_1553_2	1286171.EAL2_c09270	5.64e-69	211.0	COG1943@1|root,COG1943@2|Bacteria,1V1CM@1239|Firmicutes,24BK2@186801|Clostridia,25WUE@186806|Eubacteriaceae	186801|Clostridia	L	Transposase IS200 like	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
k141_1553_7	1121289.JHVL01000010_gene1342	3.31e-192	565.0	COG0651@1|root,COG0651@2|Bacteria,1TREH@1239|Firmicutes,248TK@186801|Clostridia,36EZ5@31979|Clostridiaceae	186801|Clostridia	CP	Proton-conducting membrane transporter	-	-	-	ko:K12137	-	-	-	-	ko00000,ko01000	-	-	-	Proton_antipo_M,Proton_antipo_N
k141_1553_8	1121289.JHVL01000010_gene1342	3.28e-184	543.0	COG0651@1|root,COG0651@2|Bacteria,1TREH@1239|Firmicutes,248TK@186801|Clostridia,36EZ5@31979|Clostridiaceae	186801|Clostridia	CP	Proton-conducting membrane transporter	-	-	-	ko:K12137	-	-	-	-	ko00000,ko01000	-	-	-	Proton_antipo_M,Proton_antipo_N
k141_1553_9	1121289.JHVL01000010_gene1343	2.19e-190	546.0	COG1009@1|root,COG1009@2|Bacteria,1TQW4@1239|Firmicutes,24A16@186801|Clostridia,36FKX@31979|Clostridiaceae	186801|Clostridia	CP	NADH-Ubiquinone oxidoreductase (complex I), chain 5	-	-	-	ko:K05565,ko:K05568	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	DUF4040,Proton_antipo_M,Proton_antipo_N
k141_2008_3	1286171.EAL2_c07060	7.92e-222	627.0	COG0154@1|root,COG0154@2|Bacteria,1TP0C@1239|Firmicutes,24911@186801|Clostridia,25V2X@186806|Eubacteriaceae	186801|Clostridia	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
k141_2008_4	1286171.EAL2_c07070	3.8e-231	649.0	COG0064@1|root,COG0064@2|Bacteria,1TPG3@1239|Firmicutes,247MS@186801|Clostridia,25VHC@186806|Eubacteriaceae	186801|Clostridia	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	-	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
k141_2008_5	1168067.JAGP01000001_gene828	5.31e-48	181.0	COG2199@1|root,COG2199@2|Bacteria,1RGCV@1224|Proteobacteria,1RZ37@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,dCache_1
k141_2008_6	547045.NEISICOT_00066	1.77e-23	98.6	COG1335@1|root,COG1335@2|Bacteria,1MU5N@1224|Proteobacteria,2VJPQ@28216|Betaproteobacteria,2KR5U@206351|Neisseriales	206351|Neisseriales	Q	isochorismatase family	-	-	-	-	-	-	-	-	-	-	-	-	DUF2322,Isochorismatase
k141_2008_7	1286171.EAL2_c07080	2.93e-152	435.0	COG0601@1|root,COG0601@2|Bacteria,1TP1S@1239|Firmicutes,247IP@186801|Clostridia,25WGI@186806|Eubacteriaceae	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 10.00	oppB	-	-	ko:K02033,ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1
k141_2008_8	1121324.CLIT_10c04120	1.62e-163	464.0	COG1173@1|root,COG1173@2|Bacteria,1TP4R@1239|Firmicutes,2489T@186801|Clostridia,25SV4@186804|Peptostreptococcaceae	186801|Clostridia	EP	N-terminal TM domain of oligopeptide transport permease C	oppC	-	-	ko:K02034,ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1,OppC_N
k141_2008_9	1123009.AUID01000005_gene1619	8.34e-195	546.0	COG0444@1|root,COG0444@2|Bacteria,1TP6E@1239|Firmicutes,247NN@186801|Clostridia,2689V@186813|unclassified Clostridiales	186801|Clostridia	EP	Oligopeptide/dipeptide transporter, C-terminal region	oppD	-	-	ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
k141_2008_10	1121324.CLIT_10c04100	7.76e-189	530.0	COG4608@1|root,COG4608@2|Bacteria,1V36J@1239|Firmicutes,24C3R@186801|Clostridia,25QJ4@186804|Peptostreptococcaceae	186801|Clostridia	P	Psort location CytoplasmicMembrane, score	appF	-	-	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
k141_2008_11	1511.CLOST_0585	2.55e-244	688.0	COG4166@1|root,COG4166@2|Bacteria,1TNYQ@1239|Firmicutes,25E4B@186801|Clostridia,25QPY@186804|Peptostreptococcaceae	186801|Clostridia	E	Psort location Periplasmic, score	oppA	-	-	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	SBP_bac_5
k141_2008_12	1286171.EAL2_c07180	2.53e-99	303.0	COG0309@1|root,COG0309@2|Bacteria,1TQP4@1239|Firmicutes,24963@186801|Clostridia,25UTJ@186806|Eubacteriaceae	186801|Clostridia	O	Psort location Cytoplasmic, score	hypE	-	-	ko:K04655	-	-	-	-	ko00000	-	-	-	AIRS,AIRS_C
k141_2008_13	546270.GEMHA0001_1082	1.26e-26	123.0	COG0860@1|root,COG5263@1|root,COG0860@2|Bacteria,COG5263@2|Bacteria,1VATU@1239|Firmicutes,4HN3V@91061|Bacilli,3WG55@539002|Bacillales incertae sedis	91061|Bacilli	M	Ami_3	amiD2	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3,CW_binding_1,LysM
k141_2008_14	1286171.EAL2_c16310	9.13e-202	573.0	COG0127@1|root,COG0689@1|root,COG0127@2|Bacteria,COG0689@2|Bacteria,1TQM3@1239|Firmicutes,25E5P@186801|Clostridia,25V9T@186806|Eubacteriaceae	186801|Clostridia	J	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates	rph	-	2.7.7.56,3.6.1.66	ko:K00989,ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000,ko03016	-	-	-	Ham1p_like,RNase_PH,RNase_PH_C
k141_2008_15	1408823.AXUS01000023_gene1725	8.64e-56	179.0	COG0622@1|root,COG0622@2|Bacteria,1VA0U@1239|Firmicutes,24MMK@186801|Clostridia,25RHX@186804|Peptostreptococcaceae	186801|Clostridia	S	Phosphoesterase	yfcE1	-	-	ko:K07095	-	-	-	-	ko00000	-	-	-	Metallophos_2
k141_2008_16	1408422.JHYF01000010_gene3343	4.01e-52	171.0	COG4843@1|root,COG4843@2|Bacteria,1V14J@1239|Firmicutes,24J7S@186801|Clostridia,36IGD@31979|Clostridiaceae	186801|Clostridia	S	Uncharacterized protein conserved in bacteria (DUF2179)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2179
k141_2008_17	1286171.EAL2_c16290	1.15e-145	428.0	COG0544@1|root,COG0544@2|Bacteria,1TQQ8@1239|Firmicutes,248C3@186801|Clostridia,25VD0@186806|Eubacteriaceae	186801|Clostridia	D	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C,Trigger_N
k141_2335_1	598467.BrE312_1992	4.35e-05	45.1	COG0119@1|root,COG0119@2|Bacteria,1MUNQ@1224|Proteobacteria,1RRGA@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Belongs to the alpha-IPM synthase homocitrate synthase family	nifV	-	2.3.3.14	ko:K02594	ko00620,map00620	-	R00271	RC00004,RC00067,RC02754	ko00000,ko00001,ko01000	-	-	-	HMGL-like
k141_2335_2	1348635.BBJY01000001_gene2432	6.27e-119	351.0	COG1104@1|root,COG1104@2|Bacteria,1MU1C@1224|Proteobacteria,1RNCD@1236|Gammaproteobacteria,1XZS5@135623|Vibrionales	135623|Vibrionales	E	Aminotransferase class-V	-	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
k141_4993_1	56780.SYN_02572	4.12e-103	305.0	COG0714@1|root,COG0714@2|Bacteria,1MV5I@1224|Proteobacteria,42MTW@68525|delta/epsilon subdivisions,2WJ0J@28221|Deltaproteobacteria,2MRC6@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	AAA domain (Cdc48 subfamily)	-	-	-	-	-	-	-	-	-	-	-	-	AAA,AAA_5
k141_2903_1	1160721.RBI_I01428	3.73e-11	75.9	COG1305@1|root,COG1305@2|Bacteria,1UVFG@1239|Firmicutes,2496A@186801|Clostridia,3WIAW@541000|Ruminococcaceae	186801|Clostridia	E	Transglutaminase-like	-	-	-	-	-	-	-	-	-	-	-	-	PT-HINT,Transglut_core
k141_4001_1	545243.BAEV01000073_gene2730	1.27e-09	57.8	COG1359@1|root,COG1359@2|Bacteria,1VJ7Y@1239|Firmicutes,24RJ7@186801|Clostridia,36MX3@31979|Clostridiaceae	186801|Clostridia	S	Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	ABM
k141_4001_2	1322246.BN4_12825	1.13e-23	97.8	COG1304@1|root,COG1304@2|Bacteria,1MUEZ@1224|Proteobacteria,42N2F@68525|delta/epsilon subdivisions,2WKXN@28221|Deltaproteobacteria,2M878@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	PFAM FMN-dependent alpha-hydroxy acid dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_dh
k141_2585_1	1265505.ATUG01000002_gene2399	3.29e-09	69.7	COG0236@1|root,COG0304@1|root,COG1028@1|root,COG2070@1|root,COG3321@1|root,COG4221@1|root,COG0236@2|Bacteria,COG0304@2|Bacteria,COG1028@2|Bacteria,COG2070@2|Bacteria,COG3321@2|Bacteria,COG4221@2|Bacteria,1R89Z@1224|Proteobacteria,42NGA@68525|delta/epsilon subdivisions,2WJK3@28221|Deltaproteobacteria,2MIK4@213118|Desulfobacterales	28221|Deltaproteobacteria	IQ	Beta-ketoacyl synthase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_1,KAsynt_C_assoc,KR,Ketoacyl-synt_C,NMO,PP-binding,PS-DH,ketoacyl-synt
k141_2010_1	864073.HFRIS_012789	1.76e-27	112.0	COG4977@1|root,COG4977@2|Bacteria,1MUDK@1224|Proteobacteria	1224|Proteobacteria	K	Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain	-	-	-	-	-	-	-	-	-	-	-	-	DJ-1_PfpI,HTH_18
k141_2013_1	1123487.KB892840_gene77	5.06e-101	303.0	COG1454@1|root,COG1454@2|Bacteria,1MVPH@1224|Proteobacteria,2WH6H@28216|Betaproteobacteria,2KYP9@206389|Rhodocyclales	1224|Proteobacteria	C	Iron-containing alcohol dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Fe-ADH
k141_4003_1	1121405.dsmv_1316	1.01e-31	128.0	2C6CZ@1|root,32R7W@2|Bacteria,1RH5F@1224|Proteobacteria,42NQC@68525|delta/epsilon subdivisions,2WMFH@28221|Deltaproteobacteria,2MIVU@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF2868)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2868
k141_2904_1	55601.VANGNB10_cII0700c	3.19e-56	189.0	28IW1@1|root,2Z8UB@2|Bacteria,1N1QM@1224|Proteobacteria,1RR0J@1236|Gammaproteobacteria,1XSR0@135623|Vibrionales	135623|Vibrionales	S	F plasmid transfer operon, TraF, protein	-	-	-	-	-	-	-	-	-	-	-	-	TraF_2
k141_2904_2	223926.28809886	5.45e-78	243.0	COG2223@1|root,COG2223@2|Bacteria,1MW71@1224|Proteobacteria,1RN10@1236|Gammaproteobacteria,1XSI0@135623|Vibrionales	135623|Vibrionales	P	COG0477 Permeases of the major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
k141_1300_1	1307761.L21SP2_2651	0.0	927.0	COG0286@1|root,COG0286@2|Bacteria,2J6AA@203691|Spirochaetes	203691|Spirochaetes	V	type I restriction-modification system	hsdM	-	2.1.1.72	ko:K03427	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HsdM_N,N6_Mtase
k141_1300_2	1122211.JMLW01000001_gene2169	4.15e-191	539.0	COG3177@1|root,COG3177@2|Bacteria,1MV69@1224|Proteobacteria,1RRCR@1236|Gammaproteobacteria,1XJDM@135619|Oceanospirillales	135619|Oceanospirillales	S	Adenylyltransferase that mediates the addition of adenosine 5'-monophosphate (AMP) to specific residues of target proteins	-	-	-	-	-	-	-	-	-	-	-	-	Fic,Fic_N
k141_1300_3	1286106.MPL1_08007	4.35e-74	236.0	COG0732@1|root,COG0732@2|Bacteria,1R5R8@1224|Proteobacteria,1S9TA@1236|Gammaproteobacteria	1236|Gammaproteobacteria	V	COG0732 Restriction endonuclease S subunits	-	-	3.1.21.3	ko:K01154	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	Methylase_S
k141_905_2	945550.VISI1226_10672	3.28e-249	716.0	COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,1MVI9@1224|Proteobacteria,1RNB0@1236|Gammaproteobacteria,1XTE5@135623|Vibrionales	135623|Vibrionales	D	protein involved in exopolysaccharide biosynthesis	-	-	-	ko:K16554	ko05111,map05111	-	-	-	ko00000,ko00001,ko02000	8.A.3.1	-	-	AAA_31,GNVR,Wzz
k141_905_3	701176.VIBRN418_10268	6.68e-59	189.0	COG1596@1|root,COG1596@2|Bacteria,1MXYS@1224|Proteobacteria,1SC60@1236|Gammaproteobacteria,1Y2XB@135623|Vibrionales	135623|Vibrionales	M	COG1596 Periplasmic protein involved in polysaccharide export	-	-	-	ko:K20988	ko05111,map05111	-	-	-	ko00000,ko00001,ko02000	1.B.18	-	-	Poly_export,SLBB
k141_906_1	1348635.BBJY01000001_gene2432	1.34e-44	155.0	COG1104@1|root,COG1104@2|Bacteria,1MU1C@1224|Proteobacteria,1RNCD@1236|Gammaproteobacteria,1XZS5@135623|Vibrionales	135623|Vibrionales	E	Aminotransferase class-V	-	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
k141_906_2	1348635.BBJY01000001_gene2433	3.16e-98	295.0	COG0694@1|root,COG0822@1|root,COG0694@2|Bacteria,COG0822@2|Bacteria,1RD5K@1224|Proteobacteria,1S3P1@1236|Gammaproteobacteria,1XZVD@135623|Vibrionales	135623|Vibrionales	CO	NifU-like domain	-	-	-	ko:K13819	-	-	-	-	ko00000	-	-	-	Fer2_BFD,NifU,NifU_N
k141_4995_2	945550.VISI1226_03019	0.0	936.0	COG0119@1|root,COG0119@2|Bacteria,1MUNQ@1224|Proteobacteria,1RMWE@1236|Gammaproteobacteria,1XSXP@135623|Vibrionales	135623|Vibrionales	E	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)	leuA	GO:0003674,GO:0003824,GO:0003852,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016740,GO:0016746,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046912,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
k141_4995_3	1238450.VIBNISOn1_1430077	2.06e-62	196.0	COG0671@1|root,COG0671@2|Bacteria,1RJ1T@1224|Proteobacteria,1SAU1@1236|Gammaproteobacteria,1XWVF@135623|Vibrionales	135623|Vibrionales	I	COG0671 Membrane-associated phospholipid phosphatase	-	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
k141_4004_1	879212.DespoDRAFT_00139	3.24e-185	525.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,42MGZ@68525|delta/epsilon subdivisions,2WIY6@28221|Deltaproteobacteria,2MIS6@213118|Desulfobacterales	28221|Deltaproteobacteria	L	helicase superfamily c-terminal domain	-	-	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
k141_907_1	1280001.BAOA01000034_gene2201	1.16e-110	338.0	COG3345@1|root,COG3345@2|Bacteria,1MWTQ@1224|Proteobacteria,1RQ4M@1236|Gammaproteobacteria,1XUYH@135623|Vibrionales	135623|Vibrionales	G	COG3345 Alpha-galactosidase	-	-	3.2.1.22	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	-	R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091	RC00049,RC00059,RC00451	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_36C,Glyco_hydro_36N,Melibiase
k141_2014_1	439235.Dalk_3509	3.81e-22	101.0	COG1372@1|root,COG3209@1|root,COG1372@2|Bacteria,COG3209@2|Bacteria,1MVV1@1224|Proteobacteria,42MK6@68525|delta/epsilon subdivisions,2WKN2@28221|Deltaproteobacteria,2MIC4@213118|Desulfobacterales	28221|Deltaproteobacteria	M	RHS protein	-	-	-	-	-	-	-	-	-	-	-	-	RHS,RHS_repeat
k141_2014_3	329726.AM1_3712	1.43e-62	196.0	COG5113@1|root,COG3236@2|Bacteria,1G60B@1117|Cyanobacteria	1117|Cyanobacteria	O	protein, ribA ribD-fused	-	-	-	ko:K09935	-	-	-	-	ko00000	-	-	-	DUF1768
k141_3274_5	491952.Mar181_0190	1.23e-50	166.0	COG2259@1|root,COG2259@2|Bacteria,1N1VA@1224|Proteobacteria,1S7MH@1236|Gammaproteobacteria,1XM2H@135619|Oceanospirillales	135619|Oceanospirillales	S	DoxX family	-	-	-	ko:K15977	-	-	-	-	ko00000	-	-	-	DoxX
k141_3274_6	491952.Mar181_0191	4.68e-26	109.0	COG3219@1|root,COG3219@2|Bacteria,1QAP4@1224|Proteobacteria,1S59S@1236|Gammaproteobacteria,1XMTU@135619|Oceanospirillales	135619|Oceanospirillales	S	Putative DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF2063
k141_3274_7	876269.ARWA01000001_gene2863	1.62e-16	79.7	COG3220@1|root,COG3220@2|Bacteria,1MURE@1224|Proteobacteria,2TRZJ@28211|Alphaproteobacteria,3NAFZ@45404|Beijerinckiaceae	28211|Alphaproteobacteria	S	Protein of unknown function (DUF692)	-	-	-	ko:K09930	-	-	-	-	ko00000	-	-	-	DUF692
k141_1301_1	933262.AXAM01000006_gene1846	5.33e-207	592.0	COG0151@1|root,COG0151@2|Bacteria,1MUAH@1224|Proteobacteria,42MCI@68525|delta/epsilon subdivisions,2WJ7H@28221|Deltaproteobacteria,2MIPF@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC,GARS_A,GARS_C,GARS_N
k141_1301_2	1304885.AUEY01000050_gene1207	2.15e-45	157.0	COG0009@1|root,COG0009@2|Bacteria,1MVPM@1224|Proteobacteria,42UBZ@68525|delta/epsilon subdivisions,2WNB6@28221|Deltaproteobacteria,2MJXY@213118|Desulfobacterales	28221|Deltaproteobacteria	J	TIGRFAM Sua5 YciO YrdC YwlC family protein	-	-	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	Sua5_yciO_yrdC
k141_4005_1	1237149.C900_03499	6.62e-06	49.7	COG2319@1|root,COG4249@1|root,COG2319@2|Bacteria,COG4249@2|Bacteria,4NKC3@976|Bacteroidetes,47NP5@768503|Cytophagia	976|Bacteroidetes	S	Caspase domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C14,WD40
k141_2587_1	55601.VANGNB10_cII0212	7.19e-31	120.0	COG0443@1|root,COG0443@2|Bacteria,1MXBT@1224|Proteobacteria,1RN4U@1236|Gammaproteobacteria,1XU0W@135623|Vibrionales	135623|Vibrionales	O	COG0443 Molecular chaperone	T0747	-	-	ko:K04046	-	-	-	-	ko00000,ko03110	1.A.33	-	-	HSP70
k141_2587_2	1116375.VEJY3_21656	3.37e-181	506.0	COG0656@1|root,COG0656@2|Bacteria,1MWFS@1224|Proteobacteria,1RRAV@1236|Gammaproteobacteria,1XYG2@135623|Vibrionales	135623|Vibrionales	S	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
k141_2587_3	1219065.VPR01S_10_01480	9.34e-269	747.0	COG0578@1|root,COG0578@2|Bacteria,1MUMY@1224|Proteobacteria,1RMGP@1236|Gammaproteobacteria,1XSTC@135623|Vibrionales	135623|Vibrionales	C	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family	glpD	-	1.1.5.3	ko:K00111	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	DAO,DAO_C
k141_4996_1	1188252.AJYK01000030_gene605	2.74e-273	764.0	COG3962@1|root,COG3962@2|Bacteria,1MW0P@1224|Proteobacteria,1RQ39@1236|Gammaproteobacteria,1XT2G@135623|Vibrionales	135623|Vibrionales	E	Belongs to the TPP enzyme family	iolD	-	3.7.1.22	ko:K03336	ko00562,ko01100,ko01120,map00562,map01100,map01120	-	R08603	RC02331	ko00000,ko00001,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
k141_2905_1	1232437.KL661978_gene3863	2.53e-18	84.3	COG0329@1|root,COG0329@2|Bacteria,1MUCM@1224|Proteobacteria,42M0X@68525|delta/epsilon subdivisions,2WK4D@28221|Deltaproteobacteria,2MHXX@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
k141_2905_2	509191.AEDB02000065_gene704	1.06e-136	407.0	COG4198@1|root,COG4198@2|Bacteria,1TQ52@1239|Firmicutes,24985@186801|Clostridia,3WGM6@541000|Ruminococcaceae	186801|Clostridia	S	Protein of unknown function (DUF1015)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1015
k141_2905_3	1232437.KL662047_gene5146	1.97e-164	483.0	COG3264@1|root,COG4487@1|root,COG3264@2|Bacteria,COG4487@2|Bacteria,1MWSA@1224|Proteobacteria,42N78@68525|delta/epsilon subdivisions,2WM0M@28221|Deltaproteobacteria,2MHVS@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Mechanosensitive ion channel	-	-	-	ko:K05802	-	-	-	-	ko00000,ko02000	1.A.23.1.1	-	-	MS_channel
k141_2588_1	439235.Dalk_5096	1.7e-68	214.0	COG0138@1|root,COG0138@2|Bacteria,1N2UC@1224|Proteobacteria,42NFS@68525|delta/epsilon subdivisions,2X5JJ@28221|Deltaproteobacteria,2MIV7@213118|Desulfobacterales	28221|Deltaproteobacteria	F	MGS-like domain	-	-	-	-	-	-	-	-	-	-	-	-	AICARFT_IMPCHas,MGS
k141_2588_2	177437.HRM2_33050	2.99e-26	105.0	COG0138@1|root,COG0138@2|Bacteria,1MUDQ@1224|Proteobacteria,42MV4@68525|delta/epsilon subdivisions,2WKHZ@28221|Deltaproteobacteria,2MI2I@213118|Desulfobacterales	28221|Deltaproteobacteria	F	PFAM AICARFT IMPCHase bienzyme	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
k141_3715_1	675814.VIC_002144	4.88e-228	660.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1XSRH@135623|Vibrionales	135623|Vibrionales	T	signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
k141_3715_2	675816.VIA_001731	5.33e-155	447.0	COG1879@1|root,COG1879@2|Bacteria,1MUJU@1224|Proteobacteria,1RQ8E@1236|Gammaproteobacteria,1XT09@135623|Vibrionales	135623|Vibrionales	G	Periplasmic binding protein domain	-	-	-	ko:K10439	ko02010,ko02030,map02010,map02030	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	Peripla_BP_4
k141_1104_1	1191299.AJYX01000111_gene2916	5.62e-45	149.0	COG1881@1|root,COG1881@2|Bacteria,1N0Y4@1224|Proteobacteria,1RYVQ@1236|Gammaproteobacteria,1Y2EJ@135623|Vibrionales	135623|Vibrionales	M	phospholipid-binding protein	-	-	-	ko:K06910	-	-	-	-	ko00000	-	-	-	PBP
k141_1104_2	1280001.BAOA01000022_gene646	4.78e-111	327.0	COG2207@1|root,COG2207@2|Bacteria,1R71R@1224|Proteobacteria,1S2IV@1236|Gammaproteobacteria,1XVDP@135623|Vibrionales	135623|Vibrionales	K	COG2207 AraC-type DNA-binding domain-containing proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
k141_1104_4	880072.Desac_1232	6.99e-42	144.0	COG1846@1|root,COG1846@2|Bacteria,1N5W3@1224|Proteobacteria,42SAX@68525|delta/epsilon subdivisions,2WPUM@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	Regulatory protein MarR	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
k141_1104_5	1121396.KB893068_gene1423	0.0	1046.0	COG1033@1|root,COG1033@2|Bacteria,1MUE1@1224|Proteobacteria,42ME2@68525|delta/epsilon subdivisions,2WJRI@28221|Deltaproteobacteria,2MMR2@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Sterol-sensing domain of SREBP cleavage-activation	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	GGDEF,LolA_like,MMPL,cNMP_binding
k141_1104_6	338966.Ppro_1941	1.74e-101	304.0	COG2834@1|root,COG2834@2|Bacteria,1MXW0@1224|Proteobacteria,42QPE@68525|delta/epsilon subdivisions,2WN39@28221|Deltaproteobacteria,43VVR@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Outer membrane lipoprotein-sorting protein	-	-	-	-	-	-	-	-	-	-	-	-	LolA_like
k141_1104_7	1121396.KB893103_gene1769	1.19e-179	514.0	COG4773@1|root,COG4773@2|Bacteria,1QCTH@1224|Proteobacteria,42PPC@68525|delta/epsilon subdivisions,2WIS8@28221|Deltaproteobacteria,2MMRJ@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Receptor	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_1104_9	319224.Sputcn32_0184	8.44e-08	51.2	28U15@1|root,2ZG7F@2|Bacteria,1P6NS@1224|Proteobacteria,1SVFY@1236|Gammaproteobacteria,2QDXP@267890|Shewanellaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_487_1	575788.VS_2569	7.75e-231	652.0	COG0511@1|root,COG5016@1|root,COG0511@2|Bacteria,COG5016@2|Bacteria,1QTTG@1224|Proteobacteria,1RNG6@1236|Gammaproteobacteria,1XT1B@135623|Vibrionales	135623|Vibrionales	CI	oxaloacetate	oadA	-	4.1.1.3	ko:K01571	ko00620,ko01100,map00620,map01100	-	R00217	RC00040	ko00000,ko00001,ko01000,ko02000	3.B.1.1.1	-	-	Biotin_lipoyl,HMGL-like,PYC_OADA
k141_487_2	55601.VANGNB10_cI0455	3.5e-237	656.0	COG1883@1|root,COG1883@2|Bacteria,1MV0G@1224|Proteobacteria,1RP3W@1236|Gammaproteobacteria,1XTU0@135623|Vibrionales	135623|Vibrionales	C	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit	oadB	-	4.1.1.3	ko:K01572	ko00620,ko01100,map00620,map01100	-	R00217	RC00040	ko00000,ko00001,ko01000,ko02000	3.B.1.1.1	-	-	OAD_beta
k141_487_3	672.VV93_v1c25080	2.57e-179	504.0	COG0604@1|root,COG0604@2|Bacteria,1MX8A@1224|Proteobacteria,1RYQZ@1236|Gammaproteobacteria,1Y2F2@135623|Vibrionales	135623|Vibrionales	C	Zinc-binding dehydrogenase	-	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N_2
k141_487_4	1348635.BBJY01000002_gene3620	1.1e-62	196.0	COG1238@1|root,COG1238@2|Bacteria,1RHUV@1224|Proteobacteria,1S4XE@1236|Gammaproteobacteria,1XX13@135623|Vibrionales	135623|Vibrionales	S	membrane	yqaA	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
k141_487_5	675815.VOA_003292	0.0	1188.0	COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,1RN05@1236|Gammaproteobacteria,1XU3E@135623|Vibrionales	135623|Vibrionales	S	Insulinase (Peptidase family M16)	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
k141_487_6	945550.VISI1226_22655	5.21e-272	756.0	COG2918@1|root,COG2918@2|Bacteria,1MW9B@1224|Proteobacteria,1RPNQ@1236|Gammaproteobacteria,1XTNN@135623|Vibrionales	135623|Vibrionales	H	Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily	gshA	GO:0003674,GO:0003824,GO:0004357,GO:0006518,GO:0006575,GO:0006749,GO:0006750,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0019184,GO:0034641,GO:0042398,GO:0043043,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0051186,GO:0051188,GO:0071704,GO:1901564,GO:1901566,GO:1901576	6.3.2.2	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	M00118	R00894,R10993	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	Glu_cys_ligase
k141_487_7	345073.VC395_0574	6.59e-104	302.0	COG1854@1|root,COG1854@2|Bacteria,1MWQF@1224|Proteobacteria,1RMDZ@1236|Gammaproteobacteria,1XUCG@135623|Vibrionales	135623|Vibrionales	H	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)	luxS	GO:0008150,GO:0009372,GO:0009987,GO:0044764,GO:0051704	4.4.1.21	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	M00609	R01291	RC00069,RC01929	ko00000,ko00001,ko00002,ko01000	-	-	-	LuxS
k141_487_9	243277.VC_0559	4.03e-130	376.0	COG4137@1|root,COG4137@2|Bacteria,1R3YD@1224|Proteobacteria,1RPUQ@1236|Gammaproteobacteria,1XSTU@135623|Vibrionales	135623|Vibrionales	S	transport system, permease component	ypjD	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm
k141_487_10	1280001.BAOA01000043_gene1282	4.87e-268	741.0	COG0541@1|root,COG0541@2|Bacteria,1MVIA@1224|Proteobacteria,1RMU9@1236|Gammaproteobacteria,1XTFD@135623|Vibrionales	135623|Vibrionales	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components	ffh	-	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
k141_487_11	223926.28807531	6.67e-50	158.0	COG0228@1|root,COG0228@2|Bacteria,1MZCT@1224|Proteobacteria,1S8RT@1236|Gammaproteobacteria,1XXZF@135623|Vibrionales	135623|Vibrionales	J	Belongs to the bacterial ribosomal protein bS16 family	rpsP	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02959	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S16
k141_487_12	1238450.VIBNISOn1_1940046	1.21e-114	330.0	COG0806@1|root,COG0806@2|Bacteria,1MWQR@1224|Proteobacteria,1RNJ2@1236|Gammaproteobacteria,1XSFG@135623|Vibrionales	135623|Vibrionales	J	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes	rimM	GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360	-	ko:K02860	-	-	-	-	ko00000,ko03009	-	-	-	PRC,RimM
k141_487_13	945543.VIBR0546_05339	1.01e-169	474.0	COG0336@1|root,COG0336@2|Bacteria,1MUN1@1224|Proteobacteria,1RMWC@1236|Gammaproteobacteria,1XSG2@135623|Vibrionales	135623|Vibrionales	J	Belongs to the RNA methyltransferase TrmD family	trmD	GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	tRNA_m1G_MT
k141_487_14	796620.VIBC2010_01663	5.47e-72	217.0	COG0335@1|root,COG0335@2|Bacteria,1RH3A@1224|Proteobacteria,1S5XX@1236|Gammaproteobacteria,1XXCD@135623|Vibrionales	135623|Vibrionales	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	rplS	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
k141_487_16	1348635.BBJY01000002_gene3608	4.71e-259	718.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,1RN9T@1236|Gammaproteobacteria,1XSK2@135623|Vibrionales	135623|Vibrionales	M	Belongs to the peptidase S1C family	degQ	-	3.4.21.107	ko:K04771,ko:K04772	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ,PDZ_2,Trypsin_2
k141_487_17	1517681.HW45_02230	8.25e-62	194.0	COG3105@1|root,COG3105@2|Bacteria,1N25P@1224|Proteobacteria,1S7WW@1236|Gammaproteobacteria,1XXEQ@135623|Vibrionales	135623|Vibrionales	S	protein conserved in bacteria	yhcB	-	-	ko:K09908	-	-	-	-	ko00000	-	-	-	DUF1043
k141_487_18	55601.VANGNB10_cI2189c	1.97e-95	278.0	COG0102@1|root,COG0102@2|Bacteria,1RA11@1224|Proteobacteria,1S280@1236|Gammaproteobacteria,1XSDR@135623|Vibrionales	135623|Vibrionales	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rplM	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
k141_487_19	1219076.N646_2596	5.21e-83	246.0	COG0103@1|root,COG0103@2|Bacteria,1RD4A@1224|Proteobacteria,1S3Q7@1236|Gammaproteobacteria,1XWX8@135623|Vibrionales	135623|Vibrionales	J	Belongs to the universal ribosomal protein uS9 family	rpsI	GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
k141_487_20	945550.VISI1226_07552	1.09e-137	390.0	COG0625@1|root,COG0625@2|Bacteria,1MXJD@1224|Proteobacteria,1RP12@1236|Gammaproteobacteria,1XTQ9@135623|Vibrionales	135623|Vibrionales	O	stringent starvation protein A	sspA	-	-	ko:K03599	-	-	-	-	ko00000,ko02000,ko03021	1.A.12.3.1	-	-	GST_C,GST_N,GST_N_3
k141_487_21	1219065.VPR01S_21_00710	4.4e-72	221.0	COG2969@1|root,COG2969@2|Bacteria,1MZ2Q@1224|Proteobacteria,1S8WT@1236|Gammaproteobacteria,1XWV9@135623|Vibrionales	135623|Vibrionales	S	stringent starvation protein b	sspB	-	-	ko:K03600	-	-	-	-	ko00000,ko03021	-	-	-	SspB
k141_4144_1	96561.Dole_2193	1.24e-93	285.0	COG0451@1|root,COG0451@2|Bacteria,1PE5Z@1224|Proteobacteria,43A0H@68525|delta/epsilon subdivisions,2X262@28221|Deltaproteobacteria,2MN1V@213118|Desulfobacterales	28221|Deltaproteobacteria	M	NmrA-like family	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
k141_2433_2	1344012.ATMI01000041_gene493	1.54e-169	485.0	COG3866@1|root,COG3866@2|Bacteria,1QJFP@1224|Proteobacteria,1THF3@1236|Gammaproteobacteria,4BVNZ@82986|Tatumella	1236|Gammaproteobacteria	G	Pectate lyase	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_2433_4	1122134.KB893650_gene562	3.29e-41	150.0	2DBYQ@1|root,32TYF@2|Bacteria,1N2HM@1224|Proteobacteria,1SB6Y@1236|Gammaproteobacteria,1XQ67@135619|Oceanospirillales	135619|Oceanospirillales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_2433_5	187272.Mlg_1518	3.45e-73	241.0	COG3853@1|root,COG3853@2|Bacteria,1MY18@1224|Proteobacteria,1RZ1H@1236|Gammaproteobacteria,1X02N@135613|Chromatiales	135613|Chromatiales	P	Toxic anion resistance family protein	-	-	-	-	-	-	-	-	-	-	-	-	TelA
k141_2433_6	1333507.AUTQ01000208_gene3919	1.21e-94	318.0	COG0507@1|root,COG1112@1|root,COG0507@2|Bacteria,COG1112@2|Bacteria,1MWMG@1224|Proteobacteria,1RPEF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Superfamily I DNA and RNA helicases and helicase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_11,AAA_12,DUF559
k141_488_1	570417.WP0383	1.31e-05	52.0	COG0666@1|root,COG0666@2|Bacteria,1RBYV@1224|Proteobacteria	1224|Proteobacteria	KT	ankyrin repeat	-	-	-	-	-	-	-	-	-	-	-	-	Ank,Ank_2,Ank_3,Ank_4
k141_2771_4	1286171.EAL2_808p04630	2.81e-99	295.0	COG0745@1|root,COG0745@2|Bacteria,1TPZ0@1239|Firmicutes,2484X@186801|Clostridia,25UU1@186806|Eubacteriaceae	186801|Clostridia	K	Psort location Cytoplasmic, score	srrA	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
k141_2771_5	1286171.EAL2_808p04620	1.84e-99	318.0	COG0642@1|root,COG2205@2|Bacteria,1V10X@1239|Firmicutes,24P7E@186801|Clostridia,25ZKB@186806|Eubacteriaceae	186801|Clostridia	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
k141_4161_1	394221.Mmar10_0251	3.38e-27	124.0	COG3468@1|root,COG3468@2|Bacteria,1MVQ6@1224|Proteobacteria,2UAUP@28211|Alphaproteobacteria,43X79@69657|Hyphomonadaceae	28211|Alphaproteobacteria	MU	TIGRFAM outer membrane autotransporter barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	Autotransporter,Calx-beta
k141_5152_1	335543.Sfum_2949	9.59e-14	69.7	COG2716@1|root,COG2716@2|Bacteria,1RB6J@1224|Proteobacteria,42RTX@68525|delta/epsilon subdivisions,2WPGC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	PFAM amino acid-binding ACT domain protein	-	-	-	ko:K03567	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000	-	-	-	ACT_6
k141_2136_1	1123401.JHYQ01000010_gene2451	5.21e-84	256.0	COG2227@1|root,COG2227@2|Bacteria,1NJV4@1224|Proteobacteria,1T1GP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23
k141_514_1	1221522.B723_06815	0.000185	50.8	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,1YSTZ@136843|Pseudomonas fluorescens group	1236|Gammaproteobacteria	NT	chemotaxis, protein	VPA0491	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal
k141_4891_1	1304885.AUEY01000021_gene3462	1.2e-119	354.0	COG0427@1|root,COG0427@2|Bacteria,1MUGE@1224|Proteobacteria,42MHC@68525|delta/epsilon subdivisions,2WINZ@28221|Deltaproteobacteria,2MI87@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM Acetyl-CoA hydrolase transferase	-	-	-	-	-	-	-	-	-	-	-	iAF987.Gmet_3304	AcetylCoA_hyd_C,AcetylCoA_hydro,Acetyltransf_1
k141_5153_1	933262.AXAM01000048_gene2601	1.72e-32	131.0	COG2937@1|root,COG2937@2|Bacteria,1MWZ6@1224|Proteobacteria,42MN4@68525|delta/epsilon subdivisions,2WJJ5@28221|Deltaproteobacteria,2MHRG@213118|Desulfobacterales	28221|Deltaproteobacteria	I	Belongs to the GPAT DAPAT family	plsB	-	2.3.1.15	ko:K00631	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
k141_4162_1	1304885.AUEY01000003_gene492	8.9e-148	429.0	COG1271@1|root,COG1271@2|Bacteria,1MV60@1224|Proteobacteria,42MB8@68525|delta/epsilon subdivisions,2WIW7@28221|Deltaproteobacteria,2MID8@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM cytochrome bd ubiquinol oxidase subunit I	cydA	-	1.10.3.14	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	Cyt_bd_oxida_I
k141_1816_1	1232437.KL662043_gene2230	9.19e-14	83.6	COG2909@1|root,COG2909@2|Bacteria,1MVZZ@1224|Proteobacteria,42QAQ@68525|delta/epsilon subdivisions,2WJQN@28221|Deltaproteobacteria,2MJ4A@213118|Desulfobacterales	1224|Proteobacteria	K	Positively regulates the transcription of the maltose regulon whose gene products are responsible for uptake and catabolism of malto-oligosaccharides. Binds and recognizes a DNA motif (called the malT box) 5'-GGA TG GA-3'	malT	-	-	ko:K03556	-	-	-	-	ko00000,ko03000	-	-	-	AAA_16,GerE,TPR_19,TPR_4,TPR_8
k141_1816_2	1323663.AROI01000031_gene1904	8.26e-18	92.0	COG1073@1|root,COG1073@2|Bacteria,1R17E@1224|Proteobacteria,1T4VU@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Dienelactone hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	DLH
k141_1816_3	1304284.L21TH_0562	1.15e-10	63.5	COG0655@1|root,COG0655@2|Bacteria,1V26K@1239|Firmicutes,24IAS@186801|Clostridia,36J7E@31979|Clostridiaceae	186801|Clostridia	S	NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
k141_515_1	1046724.KB889881_gene1805	2.03e-24	102.0	COG1234@1|root,COG1234@2|Bacteria,1Q4PW@1224|Proteobacteria,1RR5K@1236|Gammaproteobacteria,46A5V@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA	rnz	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004527,GO:0004532,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016796,GO:0016891,GO:0016893,GO:0016896,GO:0031123,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0042779,GO:0042780,GO:0042781,GO:0043167,GO:0043169,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0046483,GO:0046872,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0090503,GO:0140098,GO:1901360,GO:1905267	3.1.26.11	ko:K00784	ko03013,map03013	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	Lactamase_B_2
k141_515_2	1121403.AUCV01000009_gene1444	3.62e-95	290.0	COG1690@1|root,COG1690@2|Bacteria,1MUHA@1224|Proteobacteria,42MZN@68525|delta/epsilon subdivisions,2WJGK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Belongs to the RtcB family	-	-	6.5.1.3	ko:K14415	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RtcB
k141_4892_1	177439.DP1984	8.82e-133	380.0	COG1126@1|root,COG1126@2|Bacteria,1MU9Q@1224|Proteobacteria,42M0S@68525|delta/epsilon subdivisions,2WITR@28221|Deltaproteobacteria,2MICA@213118|Desulfobacterales	28221|Deltaproteobacteria	E	ABC transporter	-	-	3.6.3.21	ko:K02028,ko:K09972,ko:K10038	ko02010,map02010	M00227,M00232,M00236	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.3,3.A.1.3.17,3.A.1.3.18,3.A.1.3.2,3.A.1.3.7,3.A.1.3.8	-	-	ABC_tran
k141_4892_2	177439.DP1983	7.84e-123	354.0	COG0765@1|root,COG0765@2|Bacteria,1MX3E@1224|Proteobacteria,42P2J@68525|delta/epsilon subdivisions,2WJ0P@28221|Deltaproteobacteria,2MJ2M@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02029,ko:K10037	ko02010,map02010	M00227,M00236	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3,3.A.1.3.2	-	-	BPD_transp_1
k141_4892_3	177439.DP1982	2.48e-61	194.0	COG0834@1|root,COG0834@2|Bacteria,1MV3Q@1224|Proteobacteria,42MKG@68525|delta/epsilon subdivisions,2WJQ7@28221|Deltaproteobacteria,2MJPG@213118|Desulfobacterales	28221|Deltaproteobacteria	ET	Bacterial periplasmic substrate-binding proteins	glnH	-	-	ko:K10036	ko02010,map02010	M00227	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3.2	-	-	SBP_bac_3
k141_516_1	1047013.AQSP01000140_gene2502	1.09e-23	105.0	COG1357@1|root,COG1357@2|Bacteria,2NPTJ@2323|unclassified Bacteria	2|Bacteria	S	Pentapeptide repeats (8 copies)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1566,Pentapeptide,Pentapeptide_4
k141_3161_1	55601.VANGNB10_cI0494c	1.58e-37	138.0	COG0617@1|root,COG0617@2|Bacteria,1MVCS@1224|Proteobacteria,1RMBG@1236|Gammaproteobacteria,1XT38@135623|Vibrionales	135623|Vibrionales	F	Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control	pcnB	-	2.7.7.19	ko:K00970	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PolyA_pol,PolyA_pol_RNAbd,PolyA_pol_arg_C
k141_3161_2	223926.28807503	4.74e-80	241.0	COG0801@1|root,COG0801@2|Bacteria,1MZH8@1224|Proteobacteria,1S63J@1236|Gammaproteobacteria,1XVS1@135623|Vibrionales	135623|Vibrionales	H	COG0801 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase	folK	-	2.7.6.3	ko:K00950	ko00790,ko01100,map00790,map01100	M00126,M00841	R03503	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HPPK
k141_3161_3	1219077.VAZ01S_054_00070	4.73e-156	441.0	COG0413@1|root,COG0413@2|Bacteria,1MU3B@1224|Proteobacteria,1RM8D@1236|Gammaproteobacteria,1XSV3@135623|Vibrionales	135623|Vibrionales	H	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate	panB	GO:0003674,GO:0003824,GO:0003864,GO:0006082,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016740,GO:0016741,GO:0016742,GO:0019752,GO:0032787,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576	2.1.2.11	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R01226	RC00022,RC00200	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_transf
k141_3161_4	701176.VIBRN418_17758	7.76e-145	414.0	COG0414@1|root,COG0414@2|Bacteria,1MV1S@1224|Proteobacteria,1RMEG@1236|Gammaproteobacteria,1XT8P@135623|Vibrionales	135623|Vibrionales	H	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate	panC	GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605	6.3.2.1	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R02473	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_ligase
k141_764_1	675806.VII_001426	7e-181	517.0	COG0840@1|root,COG0840@2|Bacteria,1R9QT@1224|Proteobacteria,1RRT3@1236|Gammaproteobacteria,1XT29@135623|Vibrionales	135623|Vibrionales	NT	methyl-accepting chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal
k141_764_2	945550.VISI1226_20041	1.69e-231	650.0	COG3025@1|root,COG3025@2|Bacteria,1MY43@1224|Proteobacteria,1RMP4@1236|Gammaproteobacteria,1XSYB@135623|Vibrionales	135623|Vibrionales	S	CYTH	ygiF	-	3.6.1.25	ko:K18446	-	-	-	-	ko00000,ko01000	-	-	-	CHAD,CYTH
k141_764_3	1191299.AJYX01000052_gene1413	4.37e-145	410.0	COG1392@1|root,COG1392@2|Bacteria,1MXY9@1224|Proteobacteria,1RQHT@1236|Gammaproteobacteria,1XU69@135623|Vibrionales	135623|Vibrionales	P	COG1392 Phosphate transport regulator (distant homolog of PhoU)	-	-	-	ko:K07220	-	-	-	-	ko00000	-	-	-	PhoU_div
k141_5156_1	760142.Hipma_0862	5.74e-49	174.0	COG0165@1|root,COG0165@2|Bacteria,1MUTU@1224|Proteobacteria,42M7Y@68525|delta/epsilon subdivisions,2WIRN@28221|Deltaproteobacteria,2M6G5@213113|Desulfurellales	28221|Deltaproteobacteria	E	Argininosuccinate lyase C-terminal	argH	GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ASL_C2,Lyase_1,NUDIX
k141_5156_2	1304885.AUEY01000037_gene2193	1.63e-230	641.0	COG0137@1|root,COG0137@2|Bacteria,1MV0Y@1224|Proteobacteria,42N81@68525|delta/epsilon subdivisions,2WJB0@28221|Deltaproteobacteria,2MIV2@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Belongs to the argininosuccinate synthase family. Type 1 subfamily	argG	GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Arginosuc_synth
k141_1818_2	1121406.JAEX01000001_gene78	1.43e-91	283.0	COG0179@1|root,COG0179@2|Bacteria,1MUPF@1224|Proteobacteria,42NS5@68525|delta/epsilon subdivisions,2WNQ5@28221|Deltaproteobacteria,2M9B0@213115|Desulfovibrionales	28221|Deltaproteobacteria	Q	Fumarylacetoacetate (FAA) hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	FAA_hydrolase
k141_4165_1	573413.Spirs_3306	3.72e-41	146.0	COG1280@1|root,COG1280@2|Bacteria	2|Bacteria	E	homoserine transmembrane transporter activity	-	GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015318,GO:0015711,GO:0015849,GO:0016020,GO:0022857,GO:0034220,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098656,GO:1903825,GO:1905039	-	-	-	-	-	-	-	-	-	-	LysE
k141_4165_2	1536770.R50345_03545	1.8e-22	92.8	COG0346@1|root,COG0346@2|Bacteria,1UUZD@1239|Firmicutes,4IC1N@91061|Bacilli,270XI@186822|Paenibacillaceae	91061|Bacilli	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
k141_765_1	394221.Mmar10_0251	3.33e-40	155.0	COG3468@1|root,COG3468@2|Bacteria,1MVQ6@1224|Proteobacteria,2UAUP@28211|Alphaproteobacteria,43X79@69657|Hyphomonadaceae	28211|Alphaproteobacteria	MU	TIGRFAM outer membrane autotransporter barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	Autotransporter,Calx-beta
k141_5157_1	455436.DS989810_gene731	2.45e-32	128.0	COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,1RM7S@1236|Gammaproteobacteria,4640S@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	COG0739 Membrane proteins related to metalloendopeptidases	yebA	-	-	-	-	-	-	-	-	-	-	-	OapA,OapA_N,Peptidase_M23
k141_517_1	439235.Dalk_4723	8.42e-167	483.0	COG2239@1|root,COG2239@2|Bacteria,1MW24@1224|Proteobacteria,42MA7@68525|delta/epsilon subdivisions,2WIPC@28221|Deltaproteobacteria,2MJ80@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Acts as a magnesium transporter	mgtE	-	-	ko:K06213	-	-	-	-	ko00000,ko02000	1.A.26.1	-	-	CBS,MgtE,MgtE_N
k141_3162_2	1233950.IW22_16715	6.5e-51	165.0	2BH7J@1|root,32B8U@2|Bacteria,4PGIB@976|Bacteroidetes,1IHCB@117743|Flavobacteriia,3ZTX4@59732|Chryseobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_5158_1	497965.Cyan7822_5299	7.39e-24	107.0	COG0642@1|root,COG0784@1|root,COG2202@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG2205@2|Bacteria,1G09B@1117|Cyanobacteria,3KH9M@43988|Cyanothece	1117|Cyanobacteria	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,PAS_3,Response_reg,dCache_1
k141_1820_1	177437.HRM2_46770	1.99e-35	131.0	COG2081@1|root,COG2081@2|Bacteria,1MUGC@1224|Proteobacteria,42N4K@68525|delta/epsilon subdivisions,2WK97@28221|Deltaproteobacteria,2MJAQ@213118|Desulfobacterales	28221|Deltaproteobacteria	S	HI0933-like protein	-	-	-	ko:K07007	-	-	-	-	ko00000	-	-	-	HI0933_like
k141_2137_1	291112.PAU_02678	5.61e-90	306.0	COG1020@1|root,COG1020@2|Bacteria,1QK4F@1224|Proteobacteria,1RPAG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	COG1020 Non-ribosomal peptide synthetase modules and related proteins	-	-	6.3.2.14	ko:K02364,ko:K04780,ko:K16126	ko01053,ko01054,ko01110,ko01130,map01053,map01054,map01110,map01130	-	R07644	RC00162,RC03046	ko00000,ko00001,ko01000,ko01008	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding,Thioesterase
k141_2137_3	590409.Dd586_3044	4.01e-119	403.0	COG1020@1|root,COG1020@2|Bacteria,1QK4F@1224|Proteobacteria,1RPAG@1236|Gammaproteobacteria,2JDTQ@204037|Dickeya	1236|Gammaproteobacteria	Q	TIGRFAM amino acid adenylation domain protein	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding,Thioesterase
k141_2138_1	1408473.JHXO01000001_gene1956	6.26e-96	284.0	COG0528@1|root,COG0528@2|Bacteria,4NE8Z@976|Bacteroidetes,2FMES@200643|Bacteroidia	976|Bacteroidetes	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	-	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
k141_1821_2	644282.Deba_2086	2.5e-07	60.1	COG0859@1|root,COG0859@2|Bacteria,1MXA2@1224|Proteobacteria,42NEW@68525|delta/epsilon subdivisions,2WJNJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM glycosyl transferase family 9	-	-	-	ko:K02843	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
k141_5159_1	880072.Desac_0333	1.14e-72	229.0	COG1321@1|root,COG1918@1|root,COG1321@2|Bacteria,COG1918@2|Bacteria,1RHIK@1224|Proteobacteria,42SAD@68525|delta/epsilon subdivisions,2WPIC@28221|Deltaproteobacteria,2MQGE@213462|Syntrophobacterales	28221|Deltaproteobacteria	K	Iron (Metal) dependent repressor, DtxR family	-	-	-	ko:K03709	-	-	-	-	ko00000,ko03000	-	-	-	Fe_dep_repr_C,Fe_dep_repress,FeoA
k141_5159_2	635013.TherJR_1511	4.09e-07	60.5	COG1315@1|root,COG1315@2|Bacteria,1TR7W@1239|Firmicutes,24B18@186801|Clostridia	186801|Clostridia	L	PALM domain HD hydrolase domain and	-	-	-	ko:K09749	-	-	-	-	ko00000	-	-	-	FapA
k141_2782_1	674977.VMC_17850	0.0	1006.0	COG0587@1|root,COG0587@2|Bacteria,1MUIF@1224|Proteobacteria,1RP0K@1236|Gammaproteobacteria,1XTXD@135623|Vibrionales	135623|Vibrionales	L	COG0587 DNA polymerase III, alpha subunit	dnaE	GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032991,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
k141_2782_3	55601.VANGNB10_cI2030c	2.68e-167	484.0	COG0037@1|root,COG0037@2|Bacteria,1MU85@1224|Proteobacteria,1RN14@1236|Gammaproteobacteria,1XTTB@135623|Vibrionales	135623|Vibrionales	J	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	6.3.4.19	ko:K04075	-	-	R09597	RC02633,RC02634	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3,TilS,TilS_C
k141_1918_3	1195246.AGRI_02630	6.52e-80	241.0	COG0454@1|root,COG0454@2|Bacteria,1RHV9@1224|Proteobacteria,1S76Y@1236|Gammaproteobacteria,468B8@72275|Alteromonadaceae	1236|Gammaproteobacteria	K	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_7
k141_1918_4	1348635.BBJY01000006_gene378	4.68e-115	335.0	COG0662@1|root,COG4977@1|root,COG0662@2|Bacteria,COG4977@2|Bacteria,1QUHI@1224|Proteobacteria,1S3BZ@1236|Gammaproteobacteria,1XW71@135623|Vibrionales	135623|Vibrionales	K	COG2207 AraC-type DNA-binding domain-containing proteins	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,HTH_18
k141_1918_5	1348635.BBJY01000006_gene377	1.33e-123	363.0	COG0697@1|root,COG0697@2|Bacteria,1MUQ7@1224|Proteobacteria,1RN1M@1236|Gammaproteobacteria,1XVHB@135623|Vibrionales	135623|Vibrionales	EG	of the drug metabolite transporter (DMT) superfamily	-	-	-	ko:K03298	-	-	-	-	ko00000,ko02000	2.A.7.3	-	-	EamA
k141_567_2	675816.VIA_003387	1.79e-192	548.0	COG1169@1|root,COG1169@2|Bacteria,1MVB7@1224|Proteobacteria,1RNSR@1236|Gammaproteobacteria,1XTAT@135623|Vibrionales	135623|Vibrionales	H	Catalyzes the conversion of chorismate to isochorismate	menF	-	5.4.4.2	ko:K02552	ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130	M00116	R01717	RC00588	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_bind
k141_567_3	55601.VANGNB10_cI1811c	6.39e-72	232.0	COG1165@1|root,COG1165@2|Bacteria,1MVMZ@1224|Proteobacteria,1RNRS@1236|Gammaproteobacteria,1XSZF@135623|Vibrionales	135623|Vibrionales	H	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)	menD	GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0008683,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0016833,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663	2.2.1.9	ko:K02551	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R08165	RC02186	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M_2,TPP_enzyme_N
k141_3932_1	558884.JRGM01000027_gene2901	3.28e-40	141.0	COG0159@1|root,COG0159@2|Bacteria,1MXJV@1224|Proteobacteria,1RMGN@1236|Gammaproteobacteria,1Y45A@135624|Aeromonadales	135624|Aeromonadales	E	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate	trpA	-	4.2.1.20	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_syntA
k141_1534_2	177439.DPPB05	3.33e-181	519.0	COG3344@1|root,COG3344@2|Bacteria,1MVI1@1224|Proteobacteria,42RS8@68525|delta/epsilon subdivisions,2X5QK@28221|Deltaproteobacteria,2MMIZ@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	GIIM,RVT_1
k141_1534_5	118166.JH976538_gene5251	5.85e-41	158.0	COG2909@1|root,COG2909@2|Bacteria,1G3UH@1117|Cyanobacteria,1HDU6@1150|Oscillatoriales	1117|Cyanobacteria	K	transcriptional regulator	-	-	-	ko:K03556	-	-	-	-	ko00000,ko03000	-	-	-	GerE
k141_4257_1	1304885.AUEY01000032_gene1991	1.56e-51	182.0	COG1578@1|root,COG1578@2|Bacteria,1R50K@1224|Proteobacteria,42Q0S@68525|delta/epsilon subdivisions,2WJ5M@28221|Deltaproteobacteria,2MIQ5@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Protein of unknown function DUF89	-	-	-	-	-	-	-	-	-	-	-	-	DUF89
k141_4257_2	95619.PM1_0218265	5.49e-94	281.0	COG0603@1|root,COG0603@2|Bacteria,1MU5V@1224|Proteobacteria,1RMG9@1236|Gammaproteobacteria	1236|Gammaproteobacteria	F	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))	queC	-	6.3.4.20	ko:K06920	ko00790,ko01100,map00790,map01100	-	R09978	RC00959	ko00000,ko00001,ko01000,ko03016	-	-	-	QueC
k141_4257_3	1304885.AUEY01000032_gene1993	6.63e-14	70.5	COG0602@1|root,COG0602@2|Bacteria,1MUJ2@1224|Proteobacteria,42RT9@68525|delta/epsilon subdivisions,2WNJ0@28221|Deltaproteobacteria,2MIGR@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds	queE	-	4.3.99.3	ko:K10026	ko00790,ko01100,map00790,map01100	-	R10002	RC02989	ko00000,ko00001,ko01000,ko03016	-	-	iAF987.Gmet_1658	Fer4_14,Radical_SAM
k141_291_1	1175306.GWL_01310	6.27e-38	135.0	COG0835@1|root,COG0835@2|Bacteria,1RAH1@1224|Proteobacteria,2VRAI@28216|Betaproteobacteria,477IR@75682|Oxalobacteraceae	28216|Betaproteobacteria	NT	chemotaxis signal transduction protein	cheW3	-	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
k141_2526_2	29495.EA26_03640	7.24e-128	368.0	COG4105@1|root,COG4105@2|Bacteria,1MVS5@1224|Proteobacteria,1RSE6@1236|Gammaproteobacteria,1XSWB@135623|Vibrionales	135623|Vibrionales	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamD	GO:0005575,GO:0005623,GO:0008104,GO:0008150,GO:0009279,GO:0009987,GO:0016020,GO:0016043,GO:0019867,GO:0030312,GO:0030313,GO:0031224,GO:0031230,GO:0031241,GO:0031246,GO:0031975,GO:0032991,GO:0033036,GO:0034613,GO:0043163,GO:0044425,GO:0044462,GO:0044464,GO:0045184,GO:0045229,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0061024,GO:0070727,GO:0071840,GO:0071944,GO:0072657,GO:0090150,GO:0098552,GO:0098796,GO:1990063	-	ko:K05807	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	YfiO
k141_823_1	1348635.BBJY01000003_gene3731	1.87e-17	77.0	COG1846@1|root,COG1846@2|Bacteria,1RF8X@1224|Proteobacteria,1S4RW@1236|Gammaproteobacteria,1XX10@135623|Vibrionales	135623|Vibrionales	K	COG1846 Transcriptional regulators	-	-	-	-	-	-	-	-	-	-	-	-	MarR
k141_823_2	1246995.AFR_17085	1.22e-34	137.0	COG5001@1|root,COG5001@2|Bacteria,2GIZF@201174|Actinobacteria,4D8UX@85008|Micromonosporales	201174|Actinobacteria	T	Signal transduction protein containing a membrane domain an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2,EAL,GGDEF,PAS,PAS_4,PAS_9
k141_580_1	1517681.HW45_08585	5.96e-45	160.0	COG1109@1|root,COG1109@2|Bacteria,1QUGD@1224|Proteobacteria,1RQME@1236|Gammaproteobacteria,1XVES@135623|Vibrionales	135623|Vibrionales	G	Phosphoglucomutase phosphomannomutase alpha beta subunit	-	-	5.4.2.8	ko:K01840	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01818	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
k141_580_3	1348635.BBJY01000003_gene3814	2.69e-191	544.0	COG0534@1|root,COG0534@2|Bacteria,1MVRV@1224|Proteobacteria,1RRDQ@1236|Gammaproteobacteria,1XSZX@135623|Vibrionales	135623|Vibrionales	V	COG0534 Na -driven multidrug efflux pump	VVA1228	-	-	-	-	-	-	-	-	-	-	-	MatE
k141_580_6	675806.VII_000412	3.12e-22	92.8	2AWAY@1|root,31N6J@2|Bacteria,1QJXU@1224|Proteobacteria,1TI00@1236|Gammaproteobacteria,1XY1V@135623|Vibrionales	135623|Vibrionales	S	Protein of unknown function (DUF2850)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2850
k141_580_7	675814.VIC_002617	4.86e-37	127.0	COG3123@1|root,COG3123@2|Bacteria,1MZ8N@1224|Proteobacteria,1S9G3@1236|Gammaproteobacteria,1XYA2@135623|Vibrionales	135623|Vibrionales	S	Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions	ppnP	-	2.4.2.1,2.4.2.2	ko:K09913	ko00230,ko00240,map00230,map00240	-	R01561,R01570,R01863,R01876,R02147,R02296,R02297	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	DUF1255
k141_580_8	674977.VMC_18910	4.55e-123	359.0	COG1741@1|root,COG1741@2|Bacteria,1MWIP@1224|Proteobacteria,1RNVM@1236|Gammaproteobacteria,1XU4P@135623|Vibrionales	135623|Vibrionales	S	Belongs to the pirin family	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin,Pirin_C
k141_3625_1	1121403.AUCV01000036_gene2919	1.98e-132	401.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,42MQJ@68525|delta/epsilon subdivisions,2WJIX@28221|Deltaproteobacteria,2MKQF@213118|Desulfobacterales	28221|Deltaproteobacteria	P	E1-E2 ATPase	-	-	3.6.3.3,3.6.3.5	ko:K01534	-	-	-	-	ko00000,ko01000	3.A.3.6	-	-	E1-E2_ATPase,Hemerythrin,Hydrolase
k141_3625_2	525897.Dbac_3332	7.39e-37	129.0	COG1846@1|root,COG1846@2|Bacteria,1N244@1224|Proteobacteria,42TYY@68525|delta/epsilon subdivisions,2WQP5@28221|Deltaproteobacteria,2MBZY@213115|Desulfovibrionales	28221|Deltaproteobacteria	K	Transcriptional regulator, marR	-	-	-	-	-	-	-	-	-	-	-	-	MarR
k141_292_1	96561.Dole_2835	2.08e-94	282.0	COG1611@1|root,COG1611@2|Bacteria,1MU6N@1224|Proteobacteria,42P56@68525|delta/epsilon subdivisions,2WK5J@28221|Deltaproteobacteria,2MHV0@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Belongs to the LOG family	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
k141_1259_3	1304866.K413DRAFT_2576	5.59e-64	200.0	COG1595@1|root,COG1595@2|Bacteria,1V8GV@1239|Firmicutes,25B12@186801|Clostridia,36WI4@31979|Clostridiaceae	186801|Clostridia	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
k141_1259_4	1280692.AUJL01000001_gene124	1.8e-38	134.0	COG5660@1|root,COG5660@2|Bacteria,1V87D@1239|Firmicutes,24NAR@186801|Clostridia,36M52@31979|Clostridiaceae	186801|Clostridia	S	Putative zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	DUF3955,zf-HC2
k141_3226_2	1511.CLOST_1117	8.24e-140	407.0	COG1744@1|root,COG1744@2|Bacteria,1TPEU@1239|Firmicutes,248QT@186801|Clostridia,25S1Q@186804|Peptostreptococcaceae	186801|Clostridia	S	ABC transporter substrate-binding protein PnrA-like	bmpA	-	-	ko:K07335	-	-	-	-	ko00000	-	-	-	Bmp
k141_3226_3	1304284.L21TH_2351	1.11e-271	755.0	COG3845@1|root,COG3845@2|Bacteria,1UYQA@1239|Firmicutes,24XN8@186801|Clostridia,36UI0@31979|Clostridiaceae	186801|Clostridia	S	ABC transporter	rbsA2	-	3.6.3.17	ko:K02056	-	M00221	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.2	-	-	ABC_tran
k141_3226_4	1511.CLOST_1120	3.48e-154	444.0	COG4603@1|root,COG4603@2|Bacteria,1TP1F@1239|Firmicutes,2494C@186801|Clostridia,25QBZ@186804|Peptostreptococcaceae	186801|Clostridia	S	Branched-chain amino acid transport system / permease component	rbsC	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
k141_3226_5	1511.CLOST_1121	1.48e-152	437.0	COG1079@1|root,COG1079@2|Bacteria,1TP8Y@1239|Firmicutes,2486N@186801|Clostridia,25R77@186804|Peptostreptococcaceae	186801|Clostridia	S	Branched-chain amino acid transport system / permease component	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
k141_3226_8	1121324.CLIT_10c02690	2.19e-61	219.0	COG1145@1|root,COG4624@1|root,COG1145@2|Bacteria,COG4624@2|Bacteria,1TRB4@1239|Firmicutes,25KCE@186801|Clostridia,25SAF@186804|Peptostreptococcaceae	186801|Clostridia	C	Putative Fe-S cluster	-	-	-	-	-	-	-	-	-	-	-	-	FeS,Fe_hyd_lg_C,Fer4
k141_3226_9	1392493.JIAB01000001_gene1043	6e-64	216.0	COG2208@1|root,COG2208@2|Bacteria,1TQUC@1239|Firmicutes,248FZ@186801|Clostridia,27JYM@186928|unclassified Lachnospiraceae	186801|Clostridia	KT	Stage II sporulation protein E (SpoIIE)	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIE
k141_3226_10	1151292.QEW_0834	0.0	1016.0	COG0441@1|root,COG0441@2|Bacteria,1TP78@1239|Firmicutes,248CH@186801|Clostridia,25QSG@186804|Peptostreptococcaceae	186801|Clostridia	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	-	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD
k141_3226_11	1121324.CLIT_10c02630	4.97e-66	204.0	COG0290@1|root,COG0290@2|Bacteria,1V1RC@1239|Firmicutes,24FUS@186801|Clostridia	186801|Clostridia	J	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins	infC	-	-	ko:K02520	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	IF3_C,IF3_N
k141_3226_12	714961.BFZC1_05668	2.4e-20	82.8	COG0291@1|root,COG0291@2|Bacteria,1VF5W@1239|Firmicutes,4HNIQ@91061|Bacilli,3IYJB@400634|Lysinibacillus	91061|Bacilli	J	Belongs to the bacterial ribosomal protein bL35 family	rpmI	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02916	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L35p
k141_3226_13	293826.Amet_1635	2.38e-67	205.0	COG0292@1|root,COG0292@2|Bacteria,1V6DB@1239|Firmicutes,24JBJ@186801|Clostridia,36ITT@31979|Clostridiaceae	186801|Clostridia	J	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit	rplT	-	-	ko:K02887	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L20
k141_3226_14	1121324.CLIT_10c02600	6.01e-203	575.0	COG0168@1|root,COG0168@2|Bacteria,1TQ4S@1239|Firmicutes,247Q3@186801|Clostridia,25T7G@186804|Peptostreptococcaceae	186801|Clostridia	P	Cation transport protein	ktrB	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
k141_3226_15	1121324.CLIT_10c02590	6.03e-111	323.0	COG0569@1|root,COG0569@2|Bacteria,1TQ9H@1239|Firmicutes,249C2@186801|Clostridia,25R8D@186804|Peptostreptococcaceae	186801|Clostridia	P	TrkA N-terminal domain protein	ktrC	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
k141_3226_16	596329.HMPREF0631_1453	1.16e-59	196.0	COG0566@1|root,COG0566@2|Bacteria,1V3JP@1239|Firmicutes,248DV@186801|Clostridia,25RAX@186804|Peptostreptococcaceae	186801|Clostridia	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	spoU	-	-	ko:K03437	-	-	-	-	ko00000,ko03016	-	-	-	SpoU_methylase,SpoU_sub_bind
k141_3226_17	500633.CLOHIR_01898	3.39e-163	466.0	COG0016@1|root,COG0016@2|Bacteria,1TPFW@1239|Firmicutes,2486E@186801|Clostridia,25R7N@186804|Peptostreptococcaceae	186801|Clostridia	J	Phenylalanyl-tRNA synthetase alpha subunit	pheS	-	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Phe_tRNA-synt_N,tRNA-synt_2d
k141_3226_18	1476973.JMMB01000007_gene583	6.4e-313	882.0	COG0072@1|root,COG0072@2|Bacteria,1TP98@1239|Firmicutes,248BJ@186801|Clostridia,25QNW@186804|Peptostreptococcaceae	186801|Clostridia	J	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily	pheT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA-synt_2d,tRNA_bind
k141_3226_19	398512.JQKC01000002_gene1797	5.31e-18	82.8	COG3027@1|root,COG3027@2|Bacteria,1VFZR@1239|Firmicutes,25B8U@186801|Clostridia,3WS5E@541000|Ruminococcaceae	186801|Clostridia	D	Cell division protein ZapA	-	-	-	ko:K09888	-	-	-	-	ko00000,ko03036	-	-	-	ZapA
k141_3226_20	1151292.QEW_1112	4.83e-187	562.0	COG0826@1|root,COG0826@2|Bacteria,1TQS1@1239|Firmicutes,24909@186801|Clostridia,25QXR@186804|Peptostreptococcaceae	186801|Clostridia	O	Peptidase, U32 family	ydcP	-	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	DUF3656,Peptidase_U32
k141_3226_21	555079.Toce_0461	2.19e-143	420.0	COG0786@1|root,COG0786@2|Bacteria,1TQA4@1239|Firmicutes,247WX@186801|Clostridia	186801|Clostridia	P	Catalyzes the sodium-dependent transport of glutamate	gltS	-	-	ko:K03312	-	-	-	-	ko00000,ko02000	2.A.27	-	-	Glt_symporter
k141_3226_22	324057.Pjdr2_2879	4.03e-40	149.0	COG4753@1|root,COG4753@2|Bacteria,1TPFP@1239|Firmicutes,4HFB4@91061|Bacilli,26SCM@186822|Paenibacillaceae	91061|Bacilli	T	YcbB domain	ycbB1	-	-	ko:K07719	ko02020,map02020	M00518	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,YcbB
k141_3226_23	555079.Toce_0459	1.18e-100	312.0	COG0642@1|root,COG2205@2|Bacteria,1UITD@1239|Firmicutes,25EZC@186801|Clostridia	186801|Clostridia	T	PFAM ATP-binding region	-	-	2.7.13.3	ko:K07717	ko02020,map02020	M00518	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c
k141_3226_24	1391646.AVSU01000001_gene282	1.28e-307	868.0	COG1193@1|root,COG1193@2|Bacteria,1TP5W@1239|Firmicutes,248YK@186801|Clostridia,25QHB@186804|Peptostreptococcaceae	186801|Clostridia	L	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity	mutS2	-	-	ko:K07456	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_V,Smr
k141_3226_25	1151292.QEW_1119	1.27e-51	167.0	COG1683@1|root,COG1683@2|Bacteria,1V700@1239|Firmicutes,24JD2@186801|Clostridia,25RKG@186804|Peptostreptococcaceae	186801|Clostridia	S	Protein of unknown function (DUF523)	-	-	-	-	-	-	-	-	-	-	-	-	DUF523
k141_3226_26	1121324.CLIT_5c00130	1.16e-142	414.0	COG1304@1|root,COG1304@2|Bacteria,1TPC4@1239|Firmicutes,249TX@186801|Clostridia,25QMN@186804|Peptostreptococcaceae	186801|Clostridia	C	dehydrogenase (FMN-dependent)	lldD	-	-	-	-	-	-	-	-	-	-	-	FMN_dh
k141_3226_27	1121324.CLIT_5c00200	2.06e-283	789.0	COG0018@1|root,COG0018@2|Bacteria,1TPEZ@1239|Firmicutes,248JZ@186801|Clostridia,25QY6@186804|Peptostreptococcaceae	186801|Clostridia	J	Arginyl-tRNA synthetase	argS	-	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
k141_3226_29	1286171.EAL2_c09060	5.79e-16	71.6	2E5P9@1|root,330DZ@2|Bacteria,1VFDT@1239|Firmicutes,24SYS@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_3226_30	445973.CLOBAR_01278	2.58e-211	608.0	COG1032@1|root,COG1032@2|Bacteria,1TPGT@1239|Firmicutes,247JS@186801|Clostridia,25T1I@186804|Peptostreptococcaceae	186801|Clostridia	C	Protein of unknown function (DUF4080)	-	-	1.21.98.3	ko:K04034	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R06268,R06269,R06270	RC00741,RC01491,RC01492	ko00000,ko00001,ko01000	-	-	-	B12-binding,DUF4080,Radical_SAM
k141_3226_31	1391646.AVSU01000001_gene288	9.59e-84	266.0	COG0457@1|root,COG0457@2|Bacteria,1V96X@1239|Firmicutes,24AK3@186801|Clostridia,25QFT@186804|Peptostreptococcaceae	186801|Clostridia	S	TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_2,TPR_8
k141_3226_33	935845.JADQ01000036_gene2929	7.79e-220	618.0	COG0446@1|root,COG0446@2|Bacteria,1TPWW@1239|Firmicutes,4H9U7@91061|Bacilli,26SYZ@186822|Paenibacillaceae	91061|Bacilli	P	NADH oxidase	nox	-	1.6.3.4	ko:K17869	-	-	-	-	ko00000,ko01000	-	-	-	Pyr_redox_2,Pyr_redox_dim
k141_3226_34	1121324.CLIT_8c00500	3.09e-137	398.0	COG0601@1|root,COG0601@2|Bacteria,1TP1S@1239|Firmicutes,247IP@186801|Clostridia,25TJK@186804|Peptostreptococcaceae	186801|Clostridia	U	Binding-protein-dependent transport system inner membrane component	oppB	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
k141_3226_35	1121324.CLIT_8c00490	9.76e-109	323.0	COG1173@1|root,COG1173@2|Bacteria,1TP4R@1239|Firmicutes,2489T@186801|Clostridia	186801|Clostridia	P	ABC-type dipeptide oligopeptide nickel transport	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
k141_3226_36	1121324.CLIT_8c00450	1.7e-244	687.0	COG0747@1|root,COG0747@2|Bacteria,1TQ6S@1239|Firmicutes,248A3@186801|Clostridia	186801|Clostridia	E	Family 5	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
k141_3226_37	879305.HMPREF9290_1598	1.19e-84	276.0	COG2804@1|root,COG2804@2|Bacteria,1TPGE@1239|Firmicutes,247KA@186801|Clostridia,22G68@1570339|Peptoniphilaceae	186801|Clostridia	NU	Type II IV secretion system protein	gspE	-	-	ko:K02454,ko:K02652	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSE,T2SSE_N
k141_4645_1	96561.Dole_2275	0.0	887.0	COG0069@1|root,COG1145@1|root,COG0069@2|Bacteria,COG1145@2|Bacteria,1MU7B@1224|Proteobacteria,42MF7@68525|delta/epsilon subdivisions,2WJ17@28221|Deltaproteobacteria,2MJ5Y@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Belongs to the glutamate synthase family	-	-	1.4.1.13,1.4.1.14	ko:K00265	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	Fer4,Fer4_16,Glu_synthase
k141_4645_2	1121405.dsmv_2721	3.83e-188	532.0	COG0067@1|root,COG0067@2|Bacteria,1MW6C@1224|Proteobacteria,42MTE@68525|delta/epsilon subdivisions,2WJ9E@28221|Deltaproteobacteria,2MI1S@213118|Desulfobacterales	28221|Deltaproteobacteria	E	glutamate synthase	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_4645_3	1123279.ATUS01000003_gene519	1.29e-139	404.0	COG2070@1|root,COG2070@2|Bacteria,1MWPC@1224|Proteobacteria,1RRA4@1236|Gammaproteobacteria,1J5CK@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	COG2070 Dioxygenases related to 2-nitropropane dioxygenase	-	-	1.13.12.16	ko:K00459	ko00910,map00910	-	R00025	RC02541,RC02759	ko00000,ko00001,ko01000	-	-	-	NMO
k141_5213_1	1187848.AJYQ01000066_gene3524	1.95e-153	447.0	COG0642@1|root,COG2205@2|Bacteria,1MUAK@1224|Proteobacteria,1RPP2@1236|Gammaproteobacteria,1XU4B@135623|Vibrionales	135623|Vibrionales	T	Signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
k141_5213_2	1348635.BBJY01000013_gene1060	6.8e-173	496.0	COG1653@1|root,COG1653@2|Bacteria,1MUYE@1224|Proteobacteria,1RRFK@1236|Gammaproteobacteria,1XSZM@135623|Vibrionales	135623|Vibrionales	G	COG1653 ABC-type sugar transport system, periplasmic component	-	-	-	ko:K17315	ko02010,map02010	M00605	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.24,3.A.1.1.30	-	-	SBP_bac_1,SBP_bac_8
k141_5213_4	1280001.BAOA01000216_gene63	4.13e-134	381.0	COG0740@1|root,COG0740@2|Bacteria,1MV46@1224|Proteobacteria,1RNR6@1236|Gammaproteobacteria,1XU75@135623|Vibrionales	135623|Vibrionales	O	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
k141_293_1	1304885.AUEY01000007_gene1350	5.91e-136	397.0	COG1032@1|root,COG1032@2|Bacteria,1PTN9@1224|Proteobacteria,42MG9@68525|delta/epsilon subdivisions,2WJYU@28221|Deltaproteobacteria,2MIRY@213118|Desulfobacterales	28221|Deltaproteobacteria	C	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
k141_824_1	1449355.JQNR01000004_gene1115	1.69e-11	74.3	COG1032@1|root,COG1032@2|Bacteria,2HGPR@201174|Actinobacteria	201174|Actinobacteria	C	Radical SAM	-	-	-	ko:K18537,ko:K21224	ko01059,ko01130,map01059,map01130	M00831	R11389	RC03430	ko00000,ko00001,ko00002	-	-	-	B12-binding,Radical_SAM
k141_824_2	331678.Cphamn1_2385	1.63e-18	88.2	COG1726@1|root,COG1726@2|Bacteria,1FEZG@1090|Chlorobi	1090|Chlorobi	C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol	nqrA	-	1.6.5.8	ko:K00346	-	-	-	-	ko00000,ko01000	-	-	-	NQRA,NQRA_SLBB
k141_581_1	318167.Sfri_1939	5.2e-133	408.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,2QAI3@267890|Shewanellaceae	1236|Gammaproteobacteria	NT	PFAM histidine kinase, HAMP region domain protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal,dCache_3
k141_4951_1	1238450.VIBNISOn1_310005	1.52e-33	128.0	COG0534@1|root,COG0534@2|Bacteria,1MVRV@1224|Proteobacteria,1RRDQ@1236|Gammaproteobacteria,1XTD2@135623|Vibrionales	135623|Vibrionales	V	Na driven multidrug efflux pump	-	-	-	-	-	-	-	-	-	-	-	-	MatE
k141_4951_2	1116375.VEJY3_01235	5.74e-102	298.0	COG0684@1|root,COG0684@2|Bacteria,1RH18@1224|Proteobacteria,1RS9U@1236|Gammaproteobacteria,1XVB5@135623|Vibrionales	135623|Vibrionales	H	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome	rraA	-	-	ko:K02553	-	-	-	-	ko00000,ko03019	-	-	-	RraA-like
k141_4951_3	55601.VANGNB10_cI2423c	1.39e-145	418.0	COG1575@1|root,COG1575@2|Bacteria,1MXQQ@1224|Proteobacteria,1RPW5@1236|Gammaproteobacteria,1XUCP@135623|Vibrionales	135623|Vibrionales	H	Belongs to the MenA family. Type 1 subfamily	menA	-	2.5.1.74	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R05617,R06858,R10757	RC02935,RC02936,RC03264	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
k141_4951_4	672.VV93_v1c27440	7.5e-273	752.0	COG1220@1|root,COG1220@2|Bacteria,1MVK9@1224|Proteobacteria,1RMYV@1236|Gammaproteobacteria,1XSGN@135623|Vibrionales	135623|Vibrionales	O	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis	hslU	GO:0003674,GO:0003824,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:0140096,GO:1901564	-	ko:K03667	-	-	-	-	ko00000,ko03110	-	-	-	AAA_2,ClpB_D2-small
k141_4951_5	243277.VC_2675	1.85e-110	320.0	COG5405@1|root,COG5405@2|Bacteria,1MVF2@1224|Proteobacteria,1RP7P@1236|Gammaproteobacteria,1XUBK@135623|Vibrionales	135623|Vibrionales	O	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery	hslV	GO:0003674,GO:0003824,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:0140096,GO:1901564	3.4.25.2	ko:K01419	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Proteasome
k141_4951_6	945543.VIBR0546_01158	3.55e-76	233.0	COG3087@1|root,COG3087@2|Bacteria,1PWIT@1224|Proteobacteria,1RNC1@1236|Gammaproteobacteria,1XVV0@135623|Vibrionales	135623|Vibrionales	D	cell division protein	ftsN	-	-	ko:K03591	-	-	-	-	ko00000,ko03036	-	-	-	SPOR
k141_4951_8	1280001.BAOA01000021_gene746	0.0	1035.0	COG1198@1|root,COG1198@2|Bacteria,1MUUZ@1224|Proteobacteria,1RPZ7@1236|Gammaproteobacteria,1XT0R@135623|Vibrionales	135623|Vibrionales	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C
k141_4951_9	672.VV93_v1c27390	1.1e-44	144.0	COG0254@1|root,COG0254@2|Bacteria,1MZ69@1224|Proteobacteria,1SCMH@1236|Gammaproteobacteria,1XYA1@135623|Vibrionales	135623|Vibrionales	J	Binds the 23S rRNA	rpmE	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02909	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31
k141_4951_10	675813.VIB_000466	5.59e-264	728.0	COG0281@1|root,COG0281@2|Bacteria,1MU0A@1224|Proteobacteria,1RN5F@1236|Gammaproteobacteria,1XSB5@135623|Vibrionales	135623|Vibrionales	C	malic enzyme	maeB	-	1.1.1.40	ko:K00029	ko00620,ko00710,ko01100,ko01120,ko01200,map00620,map00710,map01100,map01120,map01200	M00169,M00172	R00216	RC00105	ko00000,ko00001,ko00002,ko01000	-	-	-	Malic_M,malic
k141_4951_12	1219077.VAZ01S_028_00160	2.93e-72	252.0	COG2911@1|root,COG2911@2|Bacteria,1QUFI@1224|Proteobacteria,1T1X6@1236|Gammaproteobacteria,1XU6R@135623|Vibrionales	135623|Vibrionales	S	AsmA family	-	-	-	-	-	-	-	-	-	-	-	-	AsmA
k141_4951_13	1219076.N646_2316	6.26e-172	485.0	COG0454@1|root,COG0456@2|Bacteria,1R407@1224|Proteobacteria,1RPJ2@1236|Gammaproteobacteria,1XSTQ@135623|Vibrionales	135623|Vibrionales	K	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases	yiiD	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10,YiiD_C
k141_4951_15	223926.28805107	5.25e-114	338.0	COG1295@1|root,COG1295@2|Bacteria,1QICW@1224|Proteobacteria,1RMKI@1236|Gammaproteobacteria,1XUTA@135623|Vibrionales	135623|Vibrionales	S	membrane	rbn	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
k141_1950_1	1321815.HMPREF9193_01886	0.00015	47.0	COG1639@1|root,COG1639@2|Bacteria,2J5NU@203691|Spirochaetes	203691|Spirochaetes	T	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HDOD
k141_1950_2	933262.AXAM01000008_gene1932	3.07e-165	482.0	COG1921@1|root,COG1921@2|Bacteria,1MWXI@1224|Proteobacteria,42MU7@68525|delta/epsilon subdivisions,2WJFQ@28221|Deltaproteobacteria,2MIIC@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis	selA	GO:0003674,GO:0003824,GO:0004125,GO:0006139,GO:0006399,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016740,GO:0016785,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034654,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097056,GO:0140098,GO:0140101,GO:1901360,GO:1901362,GO:1901576	2.9.1.1	ko:K01042	ko00450,ko00970,map00450,map00970	-	R08219	RC01246	ko00000,ko00001,ko01000	-	-	-	Se-cys_synth_N,SelA
k141_1950_3	1265505.ATUG01000001_gene3662	9.18e-11	71.2	COG0457@1|root,COG0457@2|Bacteria,1RDNA@1224|Proteobacteria,42Q5I@68525|delta/epsilon subdivisions,2WIX0@28221|Deltaproteobacteria,2MJTP@213118|Desulfobacterales	28221|Deltaproteobacteria	T	TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,TPR_11,TPR_16,TPR_19,TPR_2,TPR_4,TPR_7,TPR_8
k141_4072_1	1140003.I573_01304	2.12e-50	181.0	COG0477@1|root,COG2814@2|Bacteria,1TPRN@1239|Firmicutes,4HBXJ@91061|Bacilli,4B0N2@81852|Enterococcaceae	91061|Bacilli	U	Sugar (and other) transporter	ydiC1	-	-	-	-	-	-	-	-	-	-	-	MFS_1
k141_960_1	879212.DespoDRAFT_01404	2.45e-46	162.0	COG0472@1|root,COG0472@2|Bacteria,1MWYW@1224|Proteobacteria,42RB1@68525|delta/epsilon subdivisions,2WMT8@28221|Deltaproteobacteria,2MJI2@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Glycosyl transferase family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_4
k141_4073_1	335543.Sfum_3679	9.69e-90	290.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2WJVV@28221|Deltaproteobacteria,2MQ80@213462|Syntrophobacterales	28221|Deltaproteobacteria	V	TIGRFAM The (Largely Gram-negative Bacterial) Hydrophobe Amphiphile Efflux-1 (HAE1) Family	acrB	-	-	ko:K03296,ko:K18138	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
k141_4380_1	1121396.KB893054_gene2436	2.02e-12	66.2	COG2003@1|root,COG2003@2|Bacteria,1MXZ5@1224|Proteobacteria,42PPW@68525|delta/epsilon subdivisions,2WM1S@28221|Deltaproteobacteria,2MIWE@213118|Desulfobacterales	28221|Deltaproteobacteria	L	Belongs to the UPF0758 family	radC	-	-	ko:K03630	-	-	-	-	ko00000	-	-	-	RadC
k141_4380_2	1121396.KB893054_gene2437	2.77e-37	127.0	2E5HT@1|root,33096@2|Bacteria,1N2JQ@1224|Proteobacteria,42TS5@68525|delta/epsilon subdivisions,2WPZC@28221|Deltaproteobacteria,2MKFA@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_4074_1	1047013.AQSP01000076_gene1475	2.58e-102	303.0	COG0190@1|root,COG0190@2|Bacteria,2NNY1@2323|unclassified Bacteria	2|Bacteria	E	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
k141_4381_1	379731.PST_2855	2.44e-29	112.0	COG1280@1|root,COG1280@2|Bacteria,1MWA1@1224|Proteobacteria,1S74W@1236|Gammaproteobacteria,1Z0DY@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	E	transporter LysE	-	-	-	-	-	-	-	-	-	-	-	-	LysE
k141_4381_2	1121396.KB893100_gene4331	6.7e-54	188.0	COG0840@1|root,COG3287@1|root,COG0840@2|Bacteria,COG3287@2|Bacteria,1MVUZ@1224|Proteobacteria,42MYH@68525|delta/epsilon subdivisions,2X5DY@28221|Deltaproteobacteria,2MMP0@213118|Desulfobacterales	28221|Deltaproteobacteria	NT	FIST N domain	-	-	-	-	-	-	-	-	-	-	-	-	FIST,FIST_C,MCPsignal
k141_4382_1	272123.Anacy_4173	1.58e-22	108.0	COG0642@1|root,COG0745@1|root,COG0784@1|root,COG2198@1|root,COG3290@1|root,COG0745@2|Bacteria,COG0784@2|Bacteria,COG2198@2|Bacteria,COG2205@2|Bacteria,COG3290@2|Bacteria,1G09B@1117|Cyanobacteria,1HMEM@1161|Nostocales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_3,HATPase_c,HisKA,Hpt,PAS_3,PAS_4,PAS_9,Response_reg,dCache_1
k141_5330_2	439235.Dalk_3615	0.0	949.0	COG0443@1|root,COG0443@2|Bacteria,1MVEN@1224|Proteobacteria,42M64@68525|delta/epsilon subdivisions,2WIWS@28221|Deltaproteobacteria,2MJ2X@213118|Desulfobacterales	28221|Deltaproteobacteria	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
k141_5330_3	83406.HDN1F_30040	1.1e-17	85.9	28P1J@1|root,2ZBXX@2|Bacteria,1REYC@1224|Proteobacteria,1SCZQ@1236|Gammaproteobacteria,1JB33@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF1722)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1722,Pyr_excise
k141_4076_1	485916.Dtox_2676	3.19e-16	89.4	COG0147@1|root,COG1021@1|root,COG0147@2|Bacteria,COG1021@2|Bacteria,1VX0S@1239|Firmicutes,25EK2@186801|Clostridia,264JP@186807|Peptococcaceae	186801|Clostridia	Q	AMP-binding enzyme C-terminal domain	-	-	2.7.7.58,6.3.2.14	ko:K02363,ko:K04783	ko01053,ko01110,ko01130,map01053,map01110,map01130	-	R07644	RC00162,RC03046	ko00000,ko00001,ko01000,ko01008	-	-	-	AMP-binding,AMP-binding_C
k141_5331_2	1132855.KB913035_gene1671	1.23e-26	102.0	COG1846@1|root,COG1846@2|Bacteria,1N0TY@1224|Proteobacteria,2VV7T@28216|Betaproteobacteria	28216|Betaproteobacteria	K	Winged helix-turn-helix DNA-binding	-	-	-	-	-	-	-	-	-	-	-	-	HTH_24
k141_962_1	558884.JRGM01000031_gene662	2.3e-36	140.0	COG2373@1|root,COG2373@2|Bacteria,1MV7J@1224|Proteobacteria,1RNRY@1236|Gammaproteobacteria,1Y5T9@135624|Aeromonadales	135624|Aeromonadales	S	Alpha-2-Macroglobulin	-	-	-	ko:K06894	-	-	-	-	ko00000	-	-	-	A2M,A2M_N,A2M_N_2,MG1
k141_962_2	1120963.KB894491_gene907	1.12e-203	603.0	COG4953@1|root,COG4953@2|Bacteria,1MUA9@1224|Proteobacteria,1RMBV@1236|Gammaproteobacteria,2Q24P@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	M	Transglycosylase	pbpC	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0008144,GO:0008150,GO:0008658,GO:0008955,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0016758,GO:0031224,GO:0031406,GO:0033218,GO:0033293,GO:0036094,GO:0043167,GO:0043168,GO:0043177,GO:0044425,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051302,GO:0051781,GO:0065007,GO:0097159,GO:1901363,GO:1901681	2.4.1.129	ko:K05367	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	iE2348C_1286.E2348C_2802,iECO111_1330.ECO111_3243,iSF_1195.SF2565	BiPBP_C,Transgly,Transpeptidase
k141_4077_2	675814.VIC_003029	5.65e-105	323.0	COG4533@1|root,COG4533@2|Bacteria,1N2NK@1224|Proteobacteria,1RP2Z@1236|Gammaproteobacteria,1XUBB@135623|Vibrionales	135623|Vibrionales	K	transport system periplasmic component	sgrR	-	-	ko:K11925	-	-	-	-	ko00000,ko03000	-	-	-	SBP_bac_5,SgrR_N
k141_963_1	1121396.KB893090_gene202	8.4e-95	292.0	COG2304@1|root,COG2304@2|Bacteria,1MUTS@1224|Proteobacteria,42R8X@68525|delta/epsilon subdivisions,2WN6U@28221|Deltaproteobacteria,2MKTC@213118|Desulfobacterales	28221|Deltaproteobacteria	S	von Willebrand factor type A domain	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA
k141_1644_2	672.VV93_v1c18400	3.13e-89	278.0	COG3768@1|root,COG3768@2|Bacteria,1MU8S@1224|Proteobacteria,1RND9@1236|Gammaproteobacteria,1XSBZ@135623|Vibrionales	135623|Vibrionales	S	membrane	ycjF	-	-	ko:K08990	-	-	-	-	ko00000	-	-	-	DUF697
k141_3316_2	55601.VANGNB10_cII0078	2.53e-131	378.0	COG3455@1|root,COG3455@2|Bacteria,1MU13@1224|Proteobacteria,1S2PW@1236|Gammaproteobacteria,1XT7V@135623|Vibrionales	135623|Vibrionales	N	VI Secretion	vasF	-	-	ko:K11892	ko03070,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	DotU
k141_3316_3	675815.VOA_001300	1.03e-254	706.0	COG3522@1|root,COG3522@2|Bacteria,1MXKE@1224|Proteobacteria,1RNCB@1236|Gammaproteobacteria,1XSC6@135623|Vibrionales	135623|Vibrionales	S	protein conserved in bacteria	-	-	-	ko:K11893	ko02025,map02025	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	T6SS_VasE
k141_3316_4	243277.VC_A0113	2.13e-82	246.0	COG3521@1|root,COG3521@2|Bacteria,1MX5E@1224|Proteobacteria,1S83T@1236|Gammaproteobacteria,1XW0C@135623|Vibrionales	135623|Vibrionales	S	protein conserved in bacteria	-	-	-	ko:K11906	ko03070,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	T6SS-SciN
k141_3316_5	55601.VANGNB10_cII0075	4.52e-165	482.0	COG3456@1|root,COG3456@2|Bacteria,1MUKE@1224|Proteobacteria,1RQGW@1236|Gammaproteobacteria,1XUQ5@135623|Vibrionales	135623|Vibrionales	T	conserved protein, contains FHA domain	-	-	-	ko:K11894	-	-	-	-	ko00000,ko02044	3.A.23.1	-	-	FHA
k141_3316_6	675815.VOA_001297	3.15e-152	437.0	COG3520@1|root,COG3520@2|Bacteria,1MWVS@1224|Proteobacteria,1RQD5@1236|Gammaproteobacteria,1XT7D@135623|Vibrionales	135623|Vibrionales	S	protein conserved in bacteria	-	-	-	ko:K11895	ko02025,map02025	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	T6SS_TssG
k141_3316_11	870967.VIS19158_07075	5.28e-56	192.0	COG0790@1|root,COG0790@2|Bacteria,1NWNM@1224|Proteobacteria,1SPQV@1236|Gammaproteobacteria,1XWUC@135623|Vibrionales	135623|Vibrionales	S	COG0790 FOG TPR repeat, SEL1 subfamily	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_2716_1	865861.AZSU01000001_gene115	1.19e-10	64.3	COG1173@1|root,COG1173@2|Bacteria,1TP4R@1239|Firmicutes,2489T@186801|Clostridia,36E1E@31979|Clostridiaceae	186801|Clostridia	EP	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N,RCC1_2
k141_2716_2	1265505.ATUG01000003_gene674	5.51e-152	435.0	COG0601@1|root,COG0601@2|Bacteria,1PX6T@1224|Proteobacteria	1224|Proteobacteria	P	COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
k141_2716_3	439496.RBY4I_4128	2.92e-96	299.0	COG0747@1|root,COG0747@2|Bacteria,1R5VB@1224|Proteobacteria,2U0FR@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	COG0747 ABC-type dipeptide transport system, periplasmic component	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5,TAT_signal
k141_3318_1	1167006.UWK_00956	2.17e-103	318.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,42MGZ@68525|delta/epsilon subdivisions,2WIY6@28221|Deltaproteobacteria,2MHSH@213118|Desulfobacterales	28221|Deltaproteobacteria	L	DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA	rhlB	-	3.6.4.13	ko:K03732	ko03018,map03018	M00394	-	-	ko00000,ko00001,ko00002,ko01000,ko03019	-	-	-	DEAD,Helicase_C,R3H
k141_3016_1	698769.JFBD01000024_gene1884	1.91e-66	207.0	arCOG05874@1|root,2ZJ01@2|Bacteria,1V450@1239|Firmicutes,4HFPA@91061|Bacilli,4C6TS@84406|Virgibacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_3016_2	244582.JQAK01000022_gene651	2.26e-05	45.8	2EKPQ@1|root,33EDG@2|Bacteria,1NMRQ@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_3016_3	411489.CLOL250_03002	4.25e-32	114.0	2DMNG@1|root,32SP1@2|Bacteria,1VAXC@1239|Firmicutes,24P9Q@186801|Clostridia,36MGA@31979|Clostridiaceae	186801|Clostridia	S	COG NOG14552 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_2717_1	55601.VANGNB10_cII0079	2.98e-223	642.0	COG0542@1|root,COG0542@2|Bacteria,1MVBH@1224|Proteobacteria,1RMZH@1236|Gammaproteobacteria,1XTVD@135623|Vibrionales	135623|Vibrionales	O	Belongs to the ClpA ClpB family	-	-	-	ko:K11907	ko02025,ko03070,map02025,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
k141_2717_2	243277.VC_A0115	2.38e-127	369.0	COG3455@1|root,COG3455@2|Bacteria,1MU13@1224|Proteobacteria,1S2PW@1236|Gammaproteobacteria,1XT7V@135623|Vibrionales	135623|Vibrionales	N	VI Secretion	vasF	-	-	ko:K11892	ko03070,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	DotU
k141_2717_4	675815.VOA_001299	3e-69	213.0	COG3521@1|root,COG3521@2|Bacteria,1MX5E@1224|Proteobacteria,1S83T@1236|Gammaproteobacteria,1XW0C@135623|Vibrionales	135623|Vibrionales	S	protein conserved in bacteria	-	-	-	ko:K11906	ko03070,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	T6SS-SciN
k141_3017_2	635013.TherJR_1090	3.78e-64	201.0	COG0778@1|root,COG0778@2|Bacteria,1V4DP@1239|Firmicutes,24HBZ@186801|Clostridia,262HG@186807|Peptococcaceae	186801|Clostridia	C	PFAM Nitroreductase	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
k141_3018_1	1121396.KB893077_gene738	3.1e-124	375.0	COG0438@1|root,COG0438@2|Bacteria,1R3Q9@1224|Proteobacteria,42MQ2@68525|delta/epsilon subdivisions,2WM1F@28221|Deltaproteobacteria,2MQ1W@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Glycosyl transferases group 1	-	-	2.4.1.345	ko:K08256	-	-	R11702	-	ko00000,ko01000,ko01003	-	GT4	-	Glyco_transf_4,Glycos_transf_1
k141_1682_1	675813.VIB_000645	8.46e-173	492.0	COG3608@1|root,COG3608@2|Bacteria,1MUAA@1224|Proteobacteria,1RNQQ@1236|Gammaproteobacteria,1XTI2@135623|Vibrionales	135623|Vibrionales	S	Succinylglutamate desuccinylase aspartoacylase family protein	-	-	-	ko:K06987	-	-	-	-	ko00000	-	-	-	AstE_AspA
k141_1682_3	1288826.MSNKSG1_00968	4.72e-51	166.0	COG4067@1|root,COG4067@2|Bacteria,1RGX8@1224|Proteobacteria,1S5YR@1236|Gammaproteobacteria,467C1@72275|Alteromonadaceae	1236|Gammaproteobacteria	O	protein conserved in archaea	-	-	-	-	-	-	-	-	-	-	-	-	Zn_protease
k141_1682_4	243277.VC_2279	4.53e-231	652.0	COG2195@1|root,COG2195@2|Bacteria,1MUWK@1224|Proteobacteria,1RP5F@1236|Gammaproteobacteria,1XT90@135623|Vibrionales	135623|Vibrionales	E	aminoacyl-histidine dipeptidase	pepD	-	-	ko:K01270	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
k141_1682_5	345073.VC395_2394	2.23e-219	615.0	COG2252@1|root,COG2252@2|Bacteria,1MUV0@1224|Proteobacteria,1RMBE@1236|Gammaproteobacteria,1XUUP@135623|Vibrionales	135623|Vibrionales	S	COG2252 Permeases	yieG	-	-	ko:K06901	-	-	-	-	ko00000,ko02000	2.A.1.40	-	-	Xan_ur_permease
k141_1682_7	945543.VIBR0546_05748	1.53e-208	587.0	COG1073@1|root,COG1073@2|Bacteria,1N5CG@1224|Proteobacteria,1RR2Y@1236|Gammaproteobacteria,1XSG1@135623|Vibrionales	135623|Vibrionales	S	Belongs to the UPF0255 family	frsA	-	-	ko:K11750	-	-	-	-	ko00000,ko01000	-	-	-	DUF1100
k141_1682_8	243277.VC_2275	2.32e-43	145.0	292QM@1|root,2ZQ8E@2|Bacteria,1N4UT@1224|Proteobacteria,1S3WH@1236|Gammaproteobacteria,1XY3C@135623|Vibrionales	135623|Vibrionales	K	Binds to the sigma-S subunit of RNA polymerase, activating expression of sigma-S-regulated genes. Stimulates RNA polymerase holoenzyme formation and may bind to several other sigma factors, such as sigma-70 and sigma-32	crl	GO:0003674,GO:0003700,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2001141	-	ko:K11926	-	-	-	-	ko00000,ko03000	-	-	-	Crl
k141_1682_9	575788.VS_2416	2.45e-214	599.0	COG0263@1|root,COG0263@2|Bacteria,1MUBG@1224|Proteobacteria,1RM7X@1236|Gammaproteobacteria,1XTWE@135623|Vibrionales	135623|Vibrionales	F	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate	proB	GO:0003674,GO:0003824,GO:0004349,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0018130,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.2.11	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	M00015	R00239	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,PUA
k141_1682_10	1191299.AJYX01000055_gene2147	6.83e-233	648.0	COG0014@1|root,COG0014@2|Bacteria,1MUGJ@1224|Proteobacteria,1RMAY@1236|Gammaproteobacteria,1XT6D@135623|Vibrionales	135623|Vibrionales	E	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate	proA	GO:0003674,GO:0003824,GO:0004350,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0018130,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.2.1.41	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	M00015	R03313	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
k141_1682_12	1348635.BBJY01000002_gene3454	5.13e-123	360.0	COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,1MUWT@1224|Proteobacteria,1RN2M@1236|Gammaproteobacteria,1XST0@135623|Vibrionales	135623|Vibrionales	H	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate	ribD	-	1.1.1.193,3.5.4.26	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C,dCMP_cyt_deam_1
k141_1684_1	1286171.EAL2_c01550	1.92e-181	512.0	COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,2485I@186801|Clostridia,25V5M@186806|Eubacteriaceae	186801|Clostridia	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
k141_3021_1	177437.HRM2_45810	7e-87	270.0	COG1301@1|root,COG1301@2|Bacteria,1MU0Q@1224|Proteobacteria,42MZ6@68525|delta/epsilon subdivisions	1224|Proteobacteria	U	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family	gltP	-	-	ko:K03309	-	-	-	-	ko00000	2.A.23	-	-	SDF
k141_2718_1	1348635.BBJY01000021_gene2824	3.92e-126	367.0	COG1076@1|root,COG1076@2|Bacteria,1N270@1224|Proteobacteria,1RP0P@1236|Gammaproteobacteria,1XSR9@135623|Vibrionales	135623|Vibrionales	O	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host	djlA	-	-	ko:K05801	-	-	-	-	ko00000,ko03110	-	-	-	DnaJ,TerB
k141_2718_2	701176.VIBRN418_11655	0.0	1072.0	COG1452@1|root,COG1452@2|Bacteria,1MUJC@1224|Proteobacteria,1RQEX@1236|Gammaproteobacteria,1XSAA@135623|Vibrionales	135623|Vibrionales	M	Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane	lptD	GO:0008150,GO:0009636,GO:0042221,GO:0050896	-	ko:K04744	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	OstA,OstA_C
k141_2718_3	29495.EA26_02650	1.42e-198	562.0	COG0760@1|root,COG0760@2|Bacteria,1MVB3@1224|Proteobacteria,1RMWU@1236|Gammaproteobacteria,1XV5K@135623|Vibrionales	135623|Vibrionales	M	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation	surA	GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0006457,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:0140096,GO:1901564	5.2.1.8	ko:K03771	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_3,SurA_N
k141_2718_4	223926.28805320	1.28e-116	342.0	COG1995@1|root,COG1995@2|Bacteria,1MX5W@1224|Proteobacteria,1RNZV@1236|Gammaproteobacteria,1XT1M@135623|Vibrionales	135623|Vibrionales	H	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)	pdxA	GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	1.1.1.262	ko:K00097	ko00750,ko01100,map00750,map01100	M00124	R05681,R05837,R07406	RC00089,RC00675,RC01475	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxA
k141_3319_1	1348635.BBJY01000021_gene2823	2.4e-212	593.0	COG0741@1|root,COG0741@2|Bacteria,1MW2T@1224|Proteobacteria,1RM9N@1236|Gammaproteobacteria,1XU51@135623|Vibrionales	135623|Vibrionales	M	Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and or cell division	mltC	-	-	ko:K08306	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	DUF3393,SLT
k141_3319_2	1111728.ATYS01000014_gene4783	4.13e-48	154.0	COG2924@1|root,COG2924@2|Bacteria,1MZ2V@1224|Proteobacteria,1S964@1236|Gammaproteobacteria	1236|Gammaproteobacteria	CO	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes	yggX	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0009987,GO:0033554,GO:0034599,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0070887	-	-	-	-	-	-	-	-	-	-	Iron_traffic
k141_3319_3	674977.VMC_12620	1.51e-195	549.0	COG1194@1|root,COG1194@2|Bacteria,1MUD4@1224|Proteobacteria,1RMBT@1236|Gammaproteobacteria,1XTX3@135623|Vibrionales	135623|Vibrionales	L	COG1194 A G-specific DNA glycosylase	mutY	-	-	ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD,NUDIX_4
k141_3319_5	55601.VANGNB10_cI0329c	1.91e-234	650.0	COG0635@1|root,COG0635@2|Bacteria,1MU76@1224|Proteobacteria,1RN6I@1236|Gammaproteobacteria,1XTWK@135623|Vibrionales	135623|Vibrionales	H	Involved in the biosynthesis of porphyrin-containing compound	yggW	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
k141_3319_6	1051646.VITU9109_25400	2.86e-117	338.0	COG0127@1|root,COG0127@2|Bacteria,1MUK5@1224|Proteobacteria,1S27C@1236|Gammaproteobacteria,1XSX5@135623|Vibrionales	135623|Vibrionales	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions	rdgB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	Ham1p_like
k141_3319_7	1348635.BBJY01000021_gene2814	1.74e-45	149.0	COG1872@1|root,COG1872@2|Bacteria,1MZ4E@1224|Proteobacteria,1S9AB@1236|Gammaproteobacteria,1XXVE@135623|Vibrionales	135623|Vibrionales	S	Belongs to the UPF0235 family	yggU	-	-	ko:K09131	-	-	-	-	ko00000	-	-	-	DUF167
k141_3319_8	55601.VANGNB10_cI0333c	2.55e-99	291.0	COG0762@1|root,COG0762@2|Bacteria,1RCZV@1224|Proteobacteria,1S6DW@1236|Gammaproteobacteria,1XTKT@135623|Vibrionales	135623|Vibrionales	S	Integral membrane protein	yggT	-	-	ko:K02221	-	-	-	-	ko00000,ko02044	-	-	-	YGGT
k141_3319_9	298386.PBPRA3144	4.78e-102	303.0	COG0345@1|root,COG0345@2|Bacteria,1R5J1@1224|Proteobacteria,1RNQK@1236|Gammaproteobacteria,1XSBY@135623|Vibrionales	135623|Vibrionales	E	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline	proC	-	1.5.1.2	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	M00015	R01248,R01251,R03291,R03293	RC00054,RC00083	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_oxidored,P5CR_dimer
k141_1685_1	1304885.AUEY01000008_gene2099	2.4e-186	534.0	COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,42M1X@68525|delta/epsilon subdivisions,2WJA2@28221|Deltaproteobacteria,2MHZK@213118|Desulfobacterales	28221|Deltaproteobacteria	EH	TIGRFAM acetolactate synthase, large subunit, biosynthetic type	ilvB	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
k141_1685_2	1304885.AUEY01000008_gene2098	1.04e-299	829.0	COG0129@1|root,COG0129@2|Bacteria,1MUTQ@1224|Proteobacteria,42N3P@68525|delta/epsilon subdivisions,2WJB7@28221|Deltaproteobacteria,2MI51@213118|Desulfobacterales	28221|Deltaproteobacteria	EG	Belongs to the IlvD Edd family	ilvD	-	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1259	ILVD_EDD
k141_1685_3	981384.AEYW01000006_gene2863	4.44e-21	103.0	COG2199@1|root,COG5002@1|root,COG3706@2|Bacteria,COG5002@2|Bacteria,1R7HC@1224|Proteobacteria	1224|Proteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF,HAMP,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_7,PAS_9,Response_reg
k141_3320_1	55601.VANGNB10_cI0236	6.05e-119	348.0	COG0545@1|root,COG0545@2|Bacteria,1RDA1@1224|Proteobacteria,1RRKU@1236|Gammaproteobacteria,1XSY6@135623|Vibrionales	135623|Vibrionales	M	COG0545 FKBP-type peptidyl-prolyl cis-trans isomerases 1	fkpA	-	5.2.1.8	ko:K03772	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C,FKBP_N
k141_3320_2	1219065.VPR01S_29_00330	1.04e-20	91.7	COG2319@1|root,COG2319@2|Bacteria,1PDT0@1224|Proteobacteria,1RV85@1236|Gammaproteobacteria,1XTYR@135623|Vibrionales	135623|Vibrionales	S	COG2319 FOG WD40 repeat	-	-	-	-	-	-	-	-	-	-	-	-	WD40
k141_1686_1	1348635.BBJY01000001_gene2507	5.06e-65	202.0	COG1845@1|root,COG1845@2|Bacteria,1MUCK@1224|Proteobacteria,1RN9D@1236|Gammaproteobacteria,1XVK1@135623|Vibrionales	135623|Vibrionales	C	oxidase, subunit	cyoC	-	-	ko:K02299	ko00190,ko01100,map00190,map01100	M00417	-	-	ko00000,ko00001,ko00002	3.D.4.5	-	-	COX3
k141_1686_2	1348635.BBJY01000001_gene2508	9.86e-44	144.0	COG3125@1|root,COG3125@2|Bacteria,1RHE5@1224|Proteobacteria,1S6KQ@1236|Gammaproteobacteria,1XY6P@135623|Vibrionales	135623|Vibrionales	C	Prokaryotic Cytochrome C oxidase subunit IV	cyoD	-	-	ko:K02300	ko00190,ko01100,map00190,map01100	M00417	-	-	ko00000,ko00001,ko00002	3.D.4.5	-	-	COX4_pro
k141_1686_3	1348635.BBJY01000001_gene2509	2.26e-152	434.0	COG0109@1|root,COG0109@2|Bacteria,1MW3S@1224|Proteobacteria,1RNHC@1236|Gammaproteobacteria,1XUYC@135623|Vibrionales	135623|Vibrionales	O	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group	cyoE	-	2.5.1.141	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	M00154	R07411	RC01786	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	-	-	-	UbiA
k141_1686_4	1219077.VAZ01S_012_00700	3.68e-49	187.0	COG2909@1|root,COG2909@2|Bacteria,1MVZZ@1224|Proteobacteria,1RN29@1236|Gammaproteobacteria,1XUE3@135623|Vibrionales	135623|Vibrionales	K	Positively regulates the transcription of the maltose regulon whose gene products are responsible for uptake and catabolism of malto-oligosaccharides. Binds and recognizes a DNA motif (called the malT box) 5'-GGA TG GA-3'	malT	GO:0003674,GO:0003700,GO:0005975,GO:0006355,GO:0008150,GO:0008152,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044238,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2001141	-	ko:K03556	-	-	-	-	ko00000,ko03000	-	-	-	GerE
k141_2721_1	177437.HRM2_48120	5.98e-231	655.0	COG0326@1|root,COG0326@2|Bacteria,1MUUE@1224|Proteobacteria,42N42@68525|delta/epsilon subdivisions,2WK62@28221|Deltaproteobacteria,2MI73@213118|Desulfobacterales	28221|Deltaproteobacteria	O	Molecular chaperone. Has ATPase activity	htpG	-	-	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	-	-	-	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	-	-	-	HATPase_c,HATPase_c_3,HSP90
k141_2721_2	907348.TresaDRAFT_0755	1.62e-20	97.8	COG3842@1|root,COG3842@2|Bacteria,2J6IQ@203691|Spirochaetes	203691|Spirochaetes	P	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system	-	-	3.6.3.30	ko:K02010,ko:K02052	ko02010,ko02024,map02010,map02024	M00190,M00193	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.10,3.A.1.11	-	-	ABC_tran,TOBE_2
k141_2721_3	1121405.dsmv_1069	9.9e-80	246.0	COG4662@1|root,COG4662@2|Bacteria,1MZVS@1224|Proteobacteria,42N6T@68525|delta/epsilon subdivisions,2WMKR@28221|Deltaproteobacteria,2MIW9@213118|Desulfobacterales	28221|Deltaproteobacteria	P	PFAM binding-protein-dependent transport systems inner membrane component	tupB	-	-	ko:K05773	ko02010,map02010	M00186	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.2,3.A.1.6.4	-	-	BPD_transp_1
k141_3022_1	1121405.dsmv_0527	5.6e-137	404.0	COG0126@1|root,COG0126@2|Bacteria,1MUNU@1224|Proteobacteria,42N4P@68525|delta/epsilon subdivisions,2WJ0B@28221|Deltaproteobacteria,2MJ55@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Belongs to the phosphoglycerate kinase family	pgk	-	2.7.2.3	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01512	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
k141_3022_3	1121405.dsmv_0525	1.44e-81	251.0	COG2003@1|root,COG2003@2|Bacteria,1MXZ5@1224|Proteobacteria,42PPW@68525|delta/epsilon subdivisions,2WM1S@28221|Deltaproteobacteria,2MIWE@213118|Desulfobacterales	28221|Deltaproteobacteria	L	Belongs to the UPF0758 family	radC	-	-	ko:K03630	-	-	-	-	ko00000	-	-	-	RadC
k141_3022_4	933262.AXAM01000009_gene1477	2.94e-143	416.0	COG0240@1|root,COG0240@2|Bacteria,1MUU3@1224|Proteobacteria,42NQB@68525|delta/epsilon subdivisions,2WIWW@28221|Deltaproteobacteria,2MIPA@213118|Desulfobacterales	28221|Deltaproteobacteria	I	PFAM NAD-dependent glycerol-3-phosphate dehydrogenase	gpsA	-	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	-	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
k141_3022_5	1121405.dsmv_0523	0.0	1028.0	COG0188@1|root,COG0188@2|Bacteria,1MUGG@1224|Proteobacteria,42KZ9@68525|delta/epsilon subdivisions,2WJBC@28221|Deltaproteobacteria,2MIKT@213118|Desulfobacterales	28221|Deltaproteobacteria	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
k141_1687_1	1211112.ALJC01000087_gene889	2.44e-23	100.0	COG2340@1|root,COG2340@2|Bacteria,1MZ84@1224|Proteobacteria,1S99N@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	protein with SCP PR1 domains	-	-	-	-	-	-	-	-	-	-	-	-	CAP
k141_1687_2	768706.Desor_4559	4.11e-174	512.0	COG0427@1|root,COG0427@2|Bacteria	2|Bacteria	C	acetyl-CoA hydrolase activity	-	-	-	ko:K18122	ko00650,ko01100,ko01200,map00650,map01100,map01200	-	R05336	RC00012,RC00014	ko00000,ko00001,ko01000	-	-	-	AcetylCoA_hyd_C,AcetylCoA_hydro
k141_3023_1	448385.sce2252	1.17e-12	63.5	COG3809@1|root,COG3809@2|Bacteria,1N33W@1224|Proteobacteria	1224|Proteobacteria	S	Transcription factor zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-TFIIB
k141_3023_3	1265505.ATUG01000001_gene3349	1.72e-63	199.0	COG1610@1|root,COG1610@2|Bacteria,1RCQA@1224|Proteobacteria,42R4Q@68525|delta/epsilon subdivisions,2WN2Z@28221|Deltaproteobacteria,2MJMD@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Yqey-like protein	-	-	-	ko:K09117	-	-	-	-	ko00000	-	-	-	YqeY
k141_3321_4	1005395.CSV86_19932	1.74e-15	82.0	COG2207@1|root,COG2207@2|Bacteria,1QKC9@1224|Proteobacteria,1RMG3@1236|Gammaproteobacteria,1YXC6@136845|Pseudomonas putida group	1236|Gammaproteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18,HTH_AraC
k141_3321_5	472759.Nhal_0806	4.88e-50	161.0	COG0073@1|root,COG0073@2|Bacteria,1RGU7@1224|Proteobacteria,1S6NH@1236|Gammaproteobacteria,1X12N@135613|Chromatiales	135613|Chromatiales	J	Putative tRNA binding domain	-	-	-	ko:K06878	-	-	-	-	ko00000	-	-	-	tRNA_bind
k141_151_2	1267534.KB906755_gene4305	9.62e-06	48.1	COG3386@1|root,COG3386@2|Bacteria,3Y3S3@57723|Acidobacteria,2JIBP@204432|Acidobacteriia	204432|Acidobacteriia	G	PFAM NHL repeat	-	-	-	-	-	-	-	-	-	-	-	-	Big_3_5,NHL
k141_2419_1	870967.VIS19158_19130	5.01e-32	118.0	COG4659@1|root,COG4659@2|Bacteria,1RDEP@1224|Proteobacteria,1RPAD@1236|Gammaproteobacteria,1XU3Z@135623|Vibrionales	135623|Vibrionales	C	Part of a membrane complex involved in electron transport	rnfG	GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0055114	-	ko:K03612	-	-	-	-	ko00000	-	-	-	FMN_bind
k141_2419_2	55601.VANGNB10_cI0883c	5.23e-181	511.0	COG4658@1|root,COG4658@2|Bacteria,1MVY6@1224|Proteobacteria,1RMEU@1236|Gammaproteobacteria,1XSQB@135623|Vibrionales	135623|Vibrionales	C	Part of a membrane complex involved in electron transport	rnfD	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0044464,GO:0055114,GO:0071944	-	ko:K03614	-	-	-	-	ko00000	-	-	-	NQR2_RnfD_RnfE
k141_2419_3	1219076.N646_1179	4.18e-254	729.0	COG4656@1|root,COG4656@2|Bacteria,1QTUI@1224|Proteobacteria,1RMIM@1236|Gammaproteobacteria,1XTPN@135623|Vibrionales	135623|Vibrionales	C	Part of a membrane complex involved in electron transport	rnfC	GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0055114	-	ko:K03615	-	-	-	-	ko00000	-	-	-	Complex1_51K,Fer4,Fer4_10,Fer4_7,RnfC_N,SLBB
k141_2419_4	29495.EA26_16405	1.67e-95	283.0	COG2878@1|root,COG2878@2|Bacteria,1MUWU@1224|Proteobacteria,1RNSJ@1236|Gammaproteobacteria,1XSHC@135623|Vibrionales	135623|Vibrionales	C	Part of a membrane complex involved in electron transport	rnfB	GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0055114	-	ko:K03616	-	-	-	-	ko00000	-	-	-	FeS,Fer4_21
k141_4815_1	439235.Dalk_3446	1.79e-170	494.0	COG0008@1|root,COG0008@2|Bacteria,1MUC8@1224|Proteobacteria,42MAX@68525|delta/epsilon subdivisions,2WJ5B@28221|Deltaproteobacteria,2MHVD@213118|Desulfobacterales	28221|Deltaproteobacteria	J	TIGRFAM glutaminyl-tRNA synthetase	glnS	-	6.1.1.18	ko:K01886	ko00970,ko01100,map00970,map01100	M00359,M00360	R03652	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	GatB_Yqey,tRNA-synt_1c,tRNA-synt_1c_C
k141_5139_1	1200792.AKYF01000021_gene5366	5.19e-87	268.0	COG4221@1|root,COG4221@2|Bacteria,1UIB4@1239|Firmicutes,4ITBS@91061|Bacilli,274QS@186822|Paenibacillaceae	91061|Bacilli	S	KR domain	pksE	-	-	-	-	-	-	-	-	-	-	-	adh_short
k141_5139_2	1265505.ATUG01000001_gene4479	1.55e-37	130.0	COG0454@1|root,COG0456@2|Bacteria,1RDVM@1224|Proteobacteria,42X40@68525|delta/epsilon subdivisions,2WSVA@28221|Deltaproteobacteria,2MMZF@213118|Desulfobacterales	28221|Deltaproteobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
k141_4816_1	869209.Tresu_0686	2.61e-37	135.0	2A94Z@1|root,30Y9C@2|Bacteria,2JBBD@203691|Spirochaetes	203691|Spirochaetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_3137_1	1304885.AUEY01000065_gene1279	6.84e-35	133.0	COG1647@1|root,COG1647@2|Bacteria,1MVZP@1224|Proteobacteria,42NBK@68525|delta/epsilon subdivisions,2WIUP@28221|Deltaproteobacteria,2MHMP@213118|Desulfobacterales	28221|Deltaproteobacteria	I	Phosphate acyltransferases	-	-	3.1.1.1	ko:K03928	-	-	-	-	ko00000,ko01000	-	-	-	Acyltransferase,Hydrolase_4
k141_5140_2	1116375.VEJY3_22216	1.71e-149	429.0	COG1454@1|root,COG1454@2|Bacteria,1MVPH@1224|Proteobacteria,1RREW@1236|Gammaproteobacteria,1XY3I@135623|Vibrionales	135623|Vibrionales	C	Iron-containing alcohol dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Fe-ADH
k141_4477_1	1116375.VEJY3_22221	5.12e-52	180.0	COG3395@1|root,COG3395@2|Bacteria,1MW4G@1224|Proteobacteria,1RYGE@1236|Gammaproteobacteria,1XZDB@135623|Vibrionales	135623|Vibrionales	S	Putative nucleotide-binding of sugar-metabolising enzyme	-	-	2.7.1.219,2.7.1.220	ko:K22129	-	-	-	-	ko00000,ko01000	-	-	-	DUF1357_C,DUF1537
k141_4477_2	1116375.VEJY3_22226	2.18e-193	541.0	COG1995@1|root,COG1995@2|Bacteria,1MX5W@1224|Proteobacteria,1RNZV@1236|Gammaproteobacteria,1XX8Y@135623|Vibrionales	135623|Vibrionales	H	Pyridoxal phosphate biosynthetic protein PdxA	-	-	1.1.1.408,1.1.1.409	ko:K22024	-	-	-	-	ko00000,ko01000	-	-	-	PdxA
k141_4477_3	1348635.BBJY01000010_gene1414	2.65e-128	370.0	COG1349@1|root,COG1349@2|Bacteria,1MUFC@1224|Proteobacteria,1RQ1M@1236|Gammaproteobacteria,1Y2J5@135623|Vibrionales	135623|Vibrionales	K	DeoR C terminal sensor domain	-	-	-	-	-	-	-	-	-	-	-	-	DeoRC,HTH_DeoR
k141_4477_4	880074.BARVI_07180	2.72e-144	429.0	COG0469@1|root,COG0469@2|Bacteria,4NEEU@976|Bacteroidetes,2FNU3@200643|Bacteroidia,22WAP@171551|Porphyromonadaceae	976|Bacteroidetes	G	Belongs to the pyruvate kinase family	pyk	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PK,PK_C
k141_4477_5	1410619.SRDD_05170	1.58e-13	65.5	COG2161@1|root,COG2161@2|Bacteria,1QF3U@1224|Proteobacteria,1TC69@1236|Gammaproteobacteria,405GN@613|Serratia	1236|Gammaproteobacteria	D	toxin-antitoxin pair type II binding	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_5142_1	1453501.JELR01000002_gene601	7.67e-78	238.0	COG4974@1|root,COG4974@2|Bacteria,1MVAN@1224|Proteobacteria,1S1WF@1236|Gammaproteobacteria,465E7@72275|Alteromonadaceae	1236|Gammaproteobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
k141_4478_1	1120998.AUFC01000012_gene544	8.77e-46	155.0	COG2197@1|root,COG2197@2|Bacteria,1TRXG@1239|Firmicutes,24FZX@186801|Clostridia,3WDBM@538999|Clostridiales incertae sedis	186801|Clostridia	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
k141_1082_1	941449.dsx2_0126	2.33e-13	69.7	COG1508@1|root,COG1508@2|Bacteria,1MW4V@1224|Proteobacteria,42M3C@68525|delta/epsilon subdivisions,2WJ21@28221|Deltaproteobacteria,2M8T1@213115|Desulfovibrionales	28221|Deltaproteobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	rpoN	-	-	ko:K03092	ko02020,ko05111,map02020,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma54_AID,Sigma54_CBD,Sigma54_DBD
k141_1082_2	1121396.KB893057_gene2505	1.01e-89	271.0	COG1137@1|root,COG1137@2|Bacteria,1MU8M@1224|Proteobacteria,42M4J@68525|delta/epsilon subdivisions,2WJM8@28221|Deltaproteobacteria,2MI5W@213118|Desulfobacterales	28221|Deltaproteobacteria	S	PFAM ABC transporter	lptB	-	-	ko:K06861	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	1.B.42.1	-	-	ABC_tran,BCA_ABC_TP_C
k141_1082_5	1122134.KB893651_gene1982	2.25e-44	152.0	COG1778@1|root,COG1778@2|Bacteria,1RH85@1224|Proteobacteria,1S6D0@1236|Gammaproteobacteria,1XJXX@135619|Oceanospirillales	135619|Oceanospirillales	S	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate	kdsC	-	3.1.3.45	ko:K03270	ko00540,ko01100,map00540,map01100	M00063	R03350	RC00017	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hydrolase,Hydrolase_3
k141_1082_6	1121396.KB893057_gene2509	4.05e-108	320.0	COG2877@1|root,COG2877@2|Bacteria,1MV91@1224|Proteobacteria,42M61@68525|delta/epsilon subdivisions,2WIXU@28221|Deltaproteobacteria,2MHNJ@213118|Desulfobacterales	28221|Deltaproteobacteria	M	3-deoxy-D-manno-octulosonic acid 8-phosphate synthase	kdsA	-	2.5.1.55	ko:K01627	ko00540,ko01100,map00540,map01100	M00063	R03254	RC00435	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	DAHP_synth_1
k141_1082_7	933262.AXAM01000066_gene1688	2.7e-138	410.0	COG0739@1|root,COG0739@2|Bacteria,1NESH@1224|Proteobacteria,42MGB@68525|delta/epsilon subdivisions,2WJ7F@28221|Deltaproteobacteria,2MI1U@213118|Desulfobacterales	28221|Deltaproteobacteria	M	PFAM peptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
k141_1082_8	1121405.dsmv_0295	3.54e-188	533.0	COG1900@1|root,COG1900@2|Bacteria,1P1MT@1224|Proteobacteria,42M1I@68525|delta/epsilon subdivisions,2WIQ2@28221|Deltaproteobacteria,2MJ1R@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Homocysteine biosynthesis enzyme, sulfur-incorporation	-	-	-	-	-	-	-	-	-	-	-	-	HcyBio
k141_1082_9	933262.AXAM01000028_gene3314	1.63e-89	269.0	COG0681@1|root,COG0681@2|Bacteria,1MXUF@1224|Proteobacteria,42NJE@68525|delta/epsilon subdivisions,2WKMA@28221|Deltaproteobacteria,2MIAI@213118|Desulfobacterales	28221|Deltaproteobacteria	U	Belongs to the peptidase S26 family	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
k141_1082_10	1304885.AUEY01000013_gene3079	8.7e-148	425.0	COG0540@1|root,COG0540@2|Bacteria,1MWAB@1224|Proteobacteria,42NMR@68525|delta/epsilon subdivisions,2WJQR@28221|Deltaproteobacteria,2MIUY@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Belongs to the ATCase OTCase family	pyrB	GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
k141_1082_11	909663.KI867150_gene1400	2.91e-75	241.0	COG0044@1|root,COG0044@2|Bacteria,1MVXY@1224|Proteobacteria,42MJ9@68525|delta/epsilon subdivisions,2WJH8@28221|Deltaproteobacteria,2MQ49@213462|Syntrophobacterales	28221|Deltaproteobacteria	F	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily	pyrC	GO:0003674,GO:0003824,GO:0004038,GO:0004151,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046390,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
k141_2421_1	397290.C810_01305	6.03e-05	44.3	COG0351@1|root,COG0351@2|Bacteria,1TQ4A@1239|Firmicutes,2483H@186801|Clostridia,27JR0@186928|unclassified Lachnospiraceae	186801|Clostridia	H	Phosphomethylpyrimidine kinase	thiD	-	2.7.1.49,2.7.4.7	ko:K00941	ko00730,ko01100,map00730,map01100	M00127	R03471,R04509	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Phos_pyr_kin
k141_2421_2	1122599.AUGR01000005_gene1877	6.32e-25	107.0	COG0742@1|root,COG0742@2|Bacteria,1MX8Z@1224|Proteobacteria,1RMIB@1236|Gammaproteobacteria,1XIK1@135619|Oceanospirillales	135619|Oceanospirillales	J	Specifically methylates the guanosine in position 1516 of 16S rRNA	rsmJ	-	2.1.1.242	ko:K15984	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SAM_MT
k141_4817_1	443152.MDG893_17852	1.7e-144	443.0	2BXCB@1|root,2Z8QU@2|Bacteria,1MZ0I@1224|Proteobacteria,1RRGR@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	3HB-oligomer hydrolase (3HBOH)	-	-	3.1.1.22	ko:K07518	ko00650,map00650	-	R00048	RC00037,RC00094	ko00000,ko00001,ko01000	-	-	-	3HBOH
k141_153_1	439235.Dalk_4478	6.84e-143	417.0	COG1454@1|root,COG1454@2|Bacteria,1MVPH@1224|Proteobacteria,42MBY@68525|delta/epsilon subdivisions,2WIR5@28221|Deltaproteobacteria,2MISX@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM Iron-containing alcohol dehydrogenase	-	-	1.1.1.1	ko:K00001,ko:K19954	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	Fe-ADH
k141_153_2	1304885.AUEY01000024_gene2730	2.82e-45	154.0	2B831@1|root,321AX@2|Bacteria,1RIGM@1224|Proteobacteria,42WHA@68525|delta/epsilon subdivisions,2WSHZ@28221|Deltaproteobacteria,2MKZH@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_153_3	66897.DJ64_23810	8.64e-06	52.4	COG1309@1|root,COG1309@2|Bacteria,2I8MS@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	avaR	-	-	-	-	-	-	-	-	-	-	-	TetR_N
k141_153_4	1304885.AUEY01000042_gene3585	3.64e-40	139.0	COG1309@1|root,COG1309@2|Bacteria,1RK62@1224|Proteobacteria,42SVK@68525|delta/epsilon subdivisions,2WP42@28221|Deltaproteobacteria,2MK3Q@213118|Desulfobacterales	28221|Deltaproteobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
k141_1436_1	298386.PBPRA1988	4.64e-150	459.0	COG0479@1|root,COG0674@1|root,COG1013@1|root,COG1014@1|root,COG0479@2|Bacteria,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,1MVM0@1224|Proteobacteria,1RNNX@1236|Gammaproteobacteria,1XVUA@135623|Vibrionales	135623|Vibrionales	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	nifJ	-	1.2.7.1	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00173,M00307	R01196,R10866	RC00004,RC02742	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	EKR,Fer4,Fer4_16,Fer4_6,PFOR_II,POR,POR_N,TPP_enzyme_C
k141_1436_2	1298593.TOL_0183	1.52e-60	187.0	COG1396@1|root,COG1396@2|Bacteria,1N2MZ@1224|Proteobacteria,1S667@1236|Gammaproteobacteria,1XMCC@135619|Oceanospirillales	135619|Oceanospirillales	K	Transcriptional	-	-	-	-	-	-	-	-	-	-	-	-	HTH_26,HTH_3
k141_1436_3	1410619.SRDD_34840	1.11e-123	363.0	COG3550@1|root,COG3550@2|Bacteria,1N458@1224|Proteobacteria,1RNYG@1236|Gammaproteobacteria,4002D@613|Serratia	1236|Gammaproteobacteria	S	Pfam:HipA_N	hipA	-	2.7.11.1	ko:K07154	-	-	-	-	ko00000,ko01000,ko01001,ko02048	-	-	-	Couple_hipA,HipA_C
k141_1436_4	1410619.SRDD_34840	2.17e-133	388.0	COG3550@1|root,COG3550@2|Bacteria,1N458@1224|Proteobacteria,1RNYG@1236|Gammaproteobacteria,4002D@613|Serratia	1236|Gammaproteobacteria	S	Pfam:HipA_N	hipA	-	2.7.11.1	ko:K07154	-	-	-	-	ko00000,ko01000,ko01001,ko02048	-	-	-	Couple_hipA,HipA_C
k141_1436_5	29495.EA26_02185	0.0	1298.0	COG0553@1|root,COG0553@2|Bacteria,1MV6M@1224|Proteobacteria,1RQ34@1236|Gammaproteobacteria,1XWU1@135623|Vibrionales	135623|Vibrionales	L	SNF2 family N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,Mrr_cat,SNF2_N
k141_1436_6	319224.Sputcn32_2895	9.42e-314	855.0	COG1373@1|root,COG1373@2|Bacteria,1MWDX@1224|Proteobacteria,1RYD6@1236|Gammaproteobacteria,2QB5G@267890|Shewanellaceae	1236|Gammaproteobacteria	S	AAA domain	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
k141_1436_7	400668.Mmwyl1_4364	9.52e-66	200.0	COG1396@1|root,COG1396@2|Bacteria,1N8VE@1224|Proteobacteria,1SDTV@1236|Gammaproteobacteria,1XKIT@135619|Oceanospirillales	135619|Oceanospirillales	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_31
k141_1436_8	715451.ambt_22050	1.07e-255	705.0	COG3550@1|root,COG3550@2|Bacteria,1N458@1224|Proteobacteria,1RMP7@1236|Gammaproteobacteria,4645K@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	HipA-like C-terminal domain	hipA	-	2.7.11.1	ko:K07154	-	-	-	-	ko00000,ko01000,ko01001,ko02048	-	-	-	Couple_hipA,HipA_C
k141_1083_1	270374.MELB17_01130	1.15e-123	366.0	COG0517@1|root,COG0517@2|Bacteria,1MXI6@1224|Proteobacteria,1S0AJ@1236|Gammaproteobacteria,46DNA@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Putative transposase	-	-	-	-	-	-	-	-	-	-	-	-	Y2_Tnp,Zn_Tnp_IS91
k141_4818_2	340099.Teth39_2201	6.17e-19	99.0	COG2203@1|root,COG2206@1|root,COG3850@1|root,COG2203@2|Bacteria,COG2206@2|Bacteria,COG3850@2|Bacteria,1UZN2@1239|Firmicutes,25EWN@186801|Clostridia,42JGJ@68295|Thermoanaerobacterales	186801|Clostridia	T	HDOD domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF3369,GAF_2,HAMP,HD,HD_5,PAS_9,Reg_prop,Response_reg,Y_Y_Y,dCache_1
k141_4482_1	1265505.ATUG01000003_gene538	6.37e-59	189.0	COG0705@1|root,COG0705@2|Bacteria,1N1Q2@1224|Proteobacteria,42UY4@68525|delta/epsilon subdivisions,2WQEK@28221|Deltaproteobacteria,2MKNT@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Rhomboid family	-	-	-	ko:K02441	-	-	-	-	ko00000	-	-	-	Rhomboid
k141_3138_1	517418.Ctha_0789	2.51e-98	296.0	COG1979@1|root,COG1979@2|Bacteria,1FFQH@1090|Chlorobi	1090|Chlorobi	C	PFAM iron-containing alcohol dehydrogenase	-	-	1.1.1.1	ko:K00001,ko:K08325	ko00010,ko00071,ko00350,ko00625,ko00626,ko00640,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00640,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R02528,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC00739,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	Fe-ADH
k141_3138_2	338963.Pcar_1102	3.23e-185	527.0	COG0477@1|root,COG2814@2|Bacteria,1MW19@1224|Proteobacteria	1224|Proteobacteria	EGP	drug resistance transporter Bcr CflA subfamily	VY92_08720	-	-	ko:K07552	-	-	-	-	ko00000,ko02000	2.A.1.2	-	-	MFS_1
k141_3138_3	1353529.M899_3137	8.25e-32	130.0	COG0339@1|root,COG0339@2|Bacteria,1MU1K@1224|Proteobacteria,42MUY@68525|delta/epsilon subdivisions,2MSN6@213481|Bdellovibrionales,2X6WF@28221|Deltaproteobacteria	213481|Bdellovibrionales	E	Peptidase family M3	dcp	-	3.4.15.5	ko:K01284	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3
k141_4820_1	1190606.AJYG01000179_gene1536	6.86e-86	266.0	COG0443@1|root,COG0443@2|Bacteria,1MXBT@1224|Proteobacteria,1RN4U@1236|Gammaproteobacteria,1XU0W@135623|Vibrionales	135623|Vibrionales	O	COG0443 Molecular chaperone	T0747	-	-	ko:K04046	-	-	-	-	ko00000,ko03110	1.A.33	-	-	HSP70
k141_5143_1	643648.Slip_0487	8e-65	203.0	COG0663@1|root,COG0663@2|Bacteria,1V6CZ@1239|Firmicutes,25KNM@186801|Clostridia,42KRX@68298|Syntrophomonadaceae	186801|Clostridia	S	Bacterial transferase hexapeptide (six repeats)	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
k141_5143_2	1304885.AUEY01000012_gene1824	2.18e-217	613.0	COG0427@1|root,COG0427@2|Bacteria,1MUGE@1224|Proteobacteria,42MHC@68525|delta/epsilon subdivisions,2WINZ@28221|Deltaproteobacteria,2MI0T@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Acetyl-CoA hydrolase/transferase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	iAF987.Gmet_3304	AcetylCoA_hyd_C,AcetylCoA_hydro,Acetyltransf_1
k141_5143_3	879212.DespoDRAFT_00845	2.29e-59	206.0	COG3829@1|root,COG3829@2|Bacteria,1N4M6@1224|Proteobacteria,42M38@68525|delta/epsilon subdivisions,2WIR0@28221|Deltaproteobacteria,2MJ85@213118|Desulfobacterales	28221|Deltaproteobacteria	T	sigma-54 factor interaction domain-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,PAS_4,PAS_9,Sigma54_activat
k141_1084_18	243277.VC_1965	4.48e-105	307.0	COG1309@1|root,COG1309@2|Bacteria,1N0XU@1224|Proteobacteria,1S91U@1236|Gammaproteobacteria,1XVJX@135623|Vibrionales	135623|Vibrionales	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	WHG
k141_1084_19	1517681.HW45_22770	4.84e-263	742.0	COG0204@1|root,COG0204@2|Bacteria,1MWDY@1224|Proteobacteria,1RRXF@1236|Gammaproteobacteria,1XT85@135623|Vibrionales	135623|Vibrionales	I	COG0477 Permeases of the major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase,MFS_1
k141_1084_20	1051646.VITU9109_09752	6.98e-143	412.0	COG2855@1|root,COG2855@2|Bacteria,1MVIP@1224|Proteobacteria,1RPSG@1236|Gammaproteobacteria,1XTQB@135623|Vibrionales	135623|Vibrionales	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	Cons_hypoth698
k141_1084_22	223926.28805920	2.48e-166	484.0	COG0318@1|root,COG0318@2|Bacteria,1MW0Y@1224|Proteobacteria,1RN35@1236|Gammaproteobacteria,1XTBP@135623|Vibrionales	135623|Vibrionales	IQ	O-succinylbenzoic acid--CoA ligase	menE	-	6.2.1.26	ko:K01911	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R04030	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	AMP-binding,AMP-binding_C
k141_1084_23	945543.VIBR0546_04167	3.31e-144	417.0	COG1441@1|root,COG1441@2|Bacteria,1MV33@1224|Proteobacteria,1RRC0@1236|Gammaproteobacteria,1XTPS@135623|Vibrionales	135623|Vibrionales	H	Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)	menC	GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663	4.2.1.113	ko:K02549	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R04031	RC01053	ko00000,ko00001,ko00002,ko01000	-	-	-	MR_MLE_C
k141_1084_25	675813.VIB_001580	8.45e-203	561.0	COG0447@1|root,COG0447@2|Bacteria,1QTZ2@1224|Proteobacteria,1T1TZ@1236|Gammaproteobacteria,1XVFY@135623|Vibrionales	135623|Vibrionales	H	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)	menB	-	4.1.3.36	ko:K01661	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R07263	RC01923	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
k141_1084_26	1348635.BBJY01000007_gene73	6.78e-86	264.0	COG2267@1|root,COG2267@2|Bacteria,1QUFU@1224|Proteobacteria,1T1XG@1236|Gammaproteobacteria,1XSP9@135623|Vibrionales	135623|Vibrionales	H	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)	menH	-	4.2.99.20	ko:K08680	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R08166	RC02148,RC02475	ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_1,Abhydrolase_6
k141_1084_27	1051646.VITU9109_15838	8.79e-214	613.0	COG1165@1|root,COG1165@2|Bacteria,1MVMZ@1224|Proteobacteria,1RNRS@1236|Gammaproteobacteria,1XSZF@135623|Vibrionales	135623|Vibrionales	H	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)	menD	GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0008683,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0016833,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663	2.2.1.9	ko:K02551	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R08165	RC02186	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M_2,TPP_enzyme_N
k141_1084_28	945543.VIBR0546_04192	1.93e-165	479.0	COG1169@1|root,COG1169@2|Bacteria,1MVB7@1224|Proteobacteria,1RNSR@1236|Gammaproteobacteria,1XTAT@135623|Vibrionales	135623|Vibrionales	H	Catalyzes the conversion of chorismate to isochorismate	menF	-	5.4.4.2	ko:K02552	ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130	M00116	R01717	RC00588	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_bind
k141_1084_29	55601.VANGNB10_cI1813	3.3e-279	764.0	COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,1RN5B@1236|Gammaproteobacteria,1XSWC@135623|Vibrionales	135623|Vibrionales	E	COG0436 Aspartate tyrosine aromatic aminotransferase	alaA	-	2.6.1.2,2.6.1.66	ko:K14260	ko00220,ko00250,ko00290,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00290,map01100,map01110,map01130,map01210,map01230	-	R00258,R01215	RC00006,RC00008,RC00036	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
k141_1084_30	675813.VIB_001593	7.69e-116	334.0	COG1896@1|root,COG1896@2|Bacteria,1MVGJ@1224|Proteobacteria,1RSED@1236|Gammaproteobacteria,1XTZK@135623|Vibrionales	135623|Vibrionales	S	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates	yfbR	-	3.1.3.89	ko:K08722	ko00240,ko01100,map00240,map01100	-	R01569,R01664,R01968,R02088,R02102,R10776	RC00017	ko00000,ko00001,ko01000	-	-	-	HD_3
k141_1084_31	243277.VC_1979	6.76e-240	668.0	COG0232@1|root,COG0232@2|Bacteria,1MVQ2@1224|Proteobacteria,1RPVJ@1236|Gammaproteobacteria,1XTWV@135623|Vibrionales	135623|Vibrionales	F	Belongs to the dGTPase family. Type 2 subfamily	dgt	GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0015949,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576	3.1.5.1	ko:K01129	ko00230,map00230	-	R01856	RC00017	ko00000,ko00001,ko01000	-	-	-	HD,HD_assoc
k141_1084_32	1348635.BBJY01000015_gene764	8.72e-246	687.0	COG0702@1|root,COG0702@2|Bacteria,1MW54@1224|Proteobacteria,1RNS7@1236|Gammaproteobacteria,1XTP2@135623|Vibrionales	135623|Vibrionales	GM	nucleoside-diphosphate-sugar epimerases	ybjT	-	-	-	-	-	-	-	-	-	-	-	DUF2867,Epimerase,NAD_binding_10
k141_1084_33	7029.ACYPI073283-PA	1.19e-39	142.0	2EN34@1|root,2SRKR@2759|Eukaryota	2759|Eukaryota	S	Hexapeptide repeat of succinyl-transferase	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep,Hexapep_2
k141_1084_35	1205908.AKXW01000117_gene1631	1.68e-92	271.0	COG0454@1|root,COG0456@2|Bacteria,1RI35@1224|Proteobacteria,1S66W@1236|Gammaproteobacteria,1XWYT@135623|Vibrionales	135623|Vibrionales	K	Acetyltransferase (GNAT) domain	-	-	-	ko:K03827	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_10
k141_1084_36	243277.VC_A0504	5.1e-49	158.0	2DZUD@1|root,32VJ8@2|Bacteria,1N044@1224|Proteobacteria,1S8TH@1236|Gammaproteobacteria,1XXVQ@135623|Vibrionales	135623|Vibrionales	S	RelB antitoxin	-	-	-	-	-	-	-	-	-	-	-	-	RelB
k141_1084_37	55601.VANGNB10_cII0520	2.01e-51	163.0	COG3668@1|root,COG3668@2|Bacteria,1MZUQ@1224|Proteobacteria,1SANN@1236|Gammaproteobacteria,1XXZC@135623|Vibrionales	135623|Vibrionales	S	ParE toxin of type II toxin-antitoxin system, parDE	-	-	-	-	-	-	-	-	-	-	-	-	ParE_toxin
k141_1084_38	1219065.VPR01S_25_00520	1.1e-260	717.0	COG3328@1|root,COG3328@2|Bacteria,1MU4P@1224|Proteobacteria,1RNB3@1236|Gammaproteobacteria,1XVNR@135623|Vibrionales	135623|Vibrionales	L	Transposase, Mutator family	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_mut
k141_753_2	55601.VANGNB10_cI1569	9.07e-127	364.0	COG1776@1|root,COG1776@2|Bacteria,1N5S9@1224|Proteobacteria,1RMT0@1236|Gammaproteobacteria,1XVBM@135623|Vibrionales	135623|Vibrionales	NT	Protein of unknown function (DUF3334)	SO2241	-	-	-	-	-	-	-	-	-	-	-	DUF3334
k141_753_3	55601.VANGNB10_cI1568c	0.0	1633.0	COG0247@1|root,COG0277@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,1MU6Y@1224|Proteobacteria,1RQX2@1236|Gammaproteobacteria,1XU87@135623|Vibrionales	135623|Vibrionales	C	COG0277 FAD FMN-containing dehydrogenases	ydiJ	-	-	-	-	-	-	-	-	-	-	-	FAD-oxidase_C,FAD_binding_4,Fer4_8
k141_753_4	991905.SL003B_4281	1.28e-14	73.6	COG2020@1|root,COG2020@2|Bacteria,1MZ7S@1224|Proteobacteria,2UBYC@28211|Alphaproteobacteria,4BSJ8@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	O	Phospholipid methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
k141_753_5	1517681.HW45_24305	1.75e-133	382.0	2BYAF@1|root,2ZWH8@2|Bacteria,1RBZ8@1224|Proteobacteria,1S2EB@1236|Gammaproteobacteria,1XTF5@135623|Vibrionales	135623|Vibrionales	S	Protein of unknown function (DUF3581)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3581
k141_753_6	1219065.VPR01S_08_00890	2.25e-103	305.0	COG2188@1|root,COG2188@2|Bacteria,1MVFM@1224|Proteobacteria,1RNPE@1236|Gammaproteobacteria,1XSSC@135623|Vibrionales	135623|Vibrionales	K	histidine utilization repressor	hutC	-	-	ko:K05836	-	-	-	-	ko00000,ko03000	-	-	-	GntR,UTRA
k141_753_7	29495.EA26_06625	7.56e-58	180.0	COG3099@1|root,COG3099@2|Bacteria,1RE1F@1224|Proteobacteria,1S43E@1236|Gammaproteobacteria,1XY16@135623|Vibrionales	135623|Vibrionales	S	Belongs to the UPF0263 family	-	-	-	ko:K09901	-	-	-	-	ko00000	-	-	-	DUF440
k141_2758_1	318161.Sden_3007	8.32e-28	113.0	COG3497@1|root,COG3497@2|Bacteria,1MX89@1224|Proteobacteria,1RQUU@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	tail sheath protein	-	-	-	ko:K06907	-	-	-	-	ko00000	-	-	-	Phage_sheath_1,Phage_sheath_1C
k141_4506_1	298386.PBPRB1940	1.34e-33	126.0	COG0534@1|root,COG0534@2|Bacteria,1R4H5@1224|Proteobacteria,1RS0B@1236|Gammaproteobacteria,1XTRQ@135623|Vibrionales	135623|Vibrionales	V	Na driven multidrug efflux pump	vmrA	-	-	-	-	-	-	-	-	-	-	-	MatE
k141_4506_2	754436.JCM19237_6127	8.12e-115	339.0	COG0583@1|root,COG0583@2|Bacteria,1MVGZ@1224|Proteobacteria,1RRFH@1236|Gammaproteobacteria,1XWES@135623|Vibrionales	135623|Vibrionales	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
k141_4506_3	1120970.AUBZ01000023_gene2804	5.06e-13	68.2	COG0191@1|root,COG0191@2|Bacteria,1MURX@1224|Proteobacteria,1RQUC@1236|Gammaproteobacteria,46402@72275|Alteromonadaceae	1236|Gammaproteobacteria	G	COG0191 Fructose tagatose bisphosphate aldolase	kbaY	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008270,GO:0009025,GO:0009987,GO:0016043,GO:0016829,GO:0016830,GO:0016832,GO:0022607,GO:0042802,GO:0043167,GO:0043169,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071840	4.1.2.13,4.1.2.40	ko:K01624,ko:K08302	ko00010,ko00030,ko00051,ko00052,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00052,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167,M00344,M00345	R01068,R01069,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	iAF1260.b3137,iAPECO1_1312.APECO1_3290,iB21_1397.B21_02955,iBWG_1329.BWG_2841,iEC042_1314.EC042_3431,iEC55989_1330.EC55989_3557,iECABU_c1320.ECABU_c35530,iECBD_1354.ECBD_0603,iECB_1328.ECB_03004,iECDH10B_1368.ECDH10B_3310,iECDH1ME8569_1439.ECDH1ME8569_3028,iECD_1391.ECD_03004,iECED1_1282.ECED1_3801,iECH74115_1262.ECH74115_4454,iECIAI1_1343.ECIAI1_3287,iECO103_1326.ECO103_3884,iECO111_1330.ECO111_3961,iECO26_1355.ECO26_4242,iECOK1_1307.ECOK1_3561,iECP_1309.ECP_3229,iECS88_1305.ECS88_3525,iECSE_1348.ECSE_3423,iECSP_1301.ECSP_4111,iECW_1372.ECW_m3407,iECs_1301.ECs4017,iEKO11_1354.EKO11_0580,iETEC_1333.ETEC_3404,iEcDH1_1363.EcDH1_0568,iEcE24377_1341.EcE24377A_3619,iEcHS_1320.EcHS_A3329,iEcolC_1368.EcolC_0561,iG2583_1286.G2583_3861,iJO1366.b3137,iJR904.b3137,iLF82_1304.LF82_1138,iNRG857_1313.NRG857_15590,iUMN146_1321.UM146_00665,iUMNK88_1353.UMNK88_3896,iUTI89_1310.UTI89_C3568,iWFL_1372.ECW_m3407,iY75_1357.Y75_RS16275,iZ_1308.Z4491,ic_1306.c3894	F_bP_aldolase
k141_4506_4	675813.VIB_000164	1.4e-266	737.0	COG0114@1|root,COG0114@2|Bacteria,1MUQI@1224|Proteobacteria,1RNUS@1236|Gammaproteobacteria,1XVJG@135623|Vibrionales	135623|Vibrionales	C	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate	fumC	-	4.2.1.2	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	M00009,M00011,M00173,M00376	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	FumaraseC_C,Lyase_1
k141_2759_1	331869.BAL199_27556	2.07e-21	103.0	COG0642@1|root,COG2205@2|Bacteria,1MW8M@1224|Proteobacteria,2TUSJ@28211|Alphaproteobacteria,4BPUS@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	T	His Kinase A (phosphoacceptor) domain	ragB	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
k141_2760_1	498211.CJA_0016	3.07e-23	104.0	COG1361@1|root,COG2372@1|root,COG4733@1|root,COG1361@2|Bacteria,COG2372@2|Bacteria,COG4733@2|Bacteria,1N837@1224|Proteobacteria,1RZXI@1236|Gammaproteobacteria,1FI0F@10|Cellvibrio	1236|Gammaproteobacteria	M	Fibronectin type III domain	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_1085_1	313612.L8106_08861	5.68e-60	210.0	COG0737@1|root,COG2911@1|root,COG2931@1|root,COG3391@1|root,COG4222@1|root,COG0737@2|Bacteria,COG2911@2|Bacteria,COG2931@2|Bacteria,COG3391@2|Bacteria,COG4222@2|Bacteria,1G0YK@1117|Cyanobacteria	1117|Cyanobacteria	K	phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	5_nucleotid_C,CHRD,DUF4114,DUF4214,Exo_endo_phos,Phytase-like,W_rich_C
k141_1085_3	1265505.ATUG01000003_gene627	3.2e-15	73.6	2E8UW@1|root,3335A@2|Bacteria,1N8I8@1224|Proteobacteria,42TGA@68525|delta/epsilon subdivisions,2WQAG@28221|Deltaproteobacteria,2MKHK@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_474_1	55601.VANGNB10_cI0135c	6.23e-36	130.0	2E5WF@1|root,330KG@2|Bacteria,1NBFB@1224|Proteobacteria,1SFXH@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_474_2	55601.VANGNB10_cI0134	2.15e-126	374.0	28I8U@1|root,2Z8BM@2|Bacteria,1R8BF@1224|Proteobacteria,1S3DN@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Beta protein	-	-	-	-	-	-	-	-	-	-	-	-	Beta_protein
k141_2518_2	29495.EA26_12920	1.38e-16	75.5	COG3691@1|root,COG3691@2|Bacteria,1NNR5@1224|Proteobacteria,1SHHC@1236|Gammaproteobacteria,1XYHA@135623|Vibrionales	135623|Vibrionales	S	protein conserved in bacteria	VPA0419	-	-	-	-	-	-	-	-	-	-	-	DUF406
k141_2518_3	641147.HMPREF9021_01656	2.73e-54	181.0	COG2084@1|root,COG2084@2|Bacteria,1RA7F@1224|Proteobacteria,2VK8R@28216|Betaproteobacteria,2KQ48@206351|Neisseriales	206351|Neisseriales	C	Belongs to the 3-hydroxyisobutyrate dehydrogenase family	-	-	1.1.1.31	ko:K00020	ko00280,ko01100,map00280,map01100	-	R05066	RC00099	ko00000,ko00001,ko01000	-	-	-	NAD_binding_11,NAD_binding_2
k141_2518_4	1340434.AXVA01000006_gene4380	9.33e-31	119.0	COG0673@1|root,COG0673@2|Bacteria,1TSWE@1239|Firmicutes,4HCQA@91061|Bacilli,1ZCI7@1386|Bacillus	91061|Bacilli	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
k141_2518_6	670292.JH26_11375	2.57e-65	209.0	COG0583@1|root,COG0583@2|Bacteria,1MU2E@1224|Proteobacteria,2TUNU@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	transcriptional regulator	-	GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031326,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1903506,GO:2000112,GO:2001141	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
k141_809_2	1280001.BAOA01000134_gene2094	5.51e-104	303.0	COG1695@1|root,COG1695@2|Bacteria,1MZYS@1224|Proteobacteria,1S9RS@1236|Gammaproteobacteria,1XV2U@135623|Vibrionales	135623|Vibrionales	K	transcriptional regulators	aphA	-	-	ko:K10917	ko02024,ko05111,map02024,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	PadR,Vir_act_alpha_C
k141_809_3	1238450.VIBNISOn1_480075	9.02e-170	477.0	COG1045@1|root,COG1045@2|Bacteria,1MVFX@1224|Proteobacteria,1RNCA@1236|Gammaproteobacteria,1XTF9@135623|Vibrionales	135623|Vibrionales	E	Serine acetyltransferase	cysE	-	2.3.1.30	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	M00021	R00586	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,SATase_N
k141_5208_1	406124.ACPC01000022_gene4198	1.74e-12	63.9	COG4576@1|root,COG4576@2|Bacteria,1VEI4@1239|Firmicutes,4IKXG@91061|Bacilli,1ZI7Q@1386|Bacillus	91061|Bacilli	CQ	Ethanolamine utilisation protein EutN/carboxysome	-	-	-	-	-	-	-	-	-	-	-	-	EutN_CcmL
k141_5208_2	207559.Dde_3272	6.46e-72	222.0	COG4577@1|root,COG4577@2|Bacteria,1NWYM@1224|Proteobacteria,4308V@68525|delta/epsilon subdivisions,2WVH0@28221|Deltaproteobacteria,2MBUY@213115|Desulfovibrionales	28221|Deltaproteobacteria	CQ	BMC	-	-	-	-	-	-	-	-	-	-	-	-	BMC
k141_5208_3	207559.Dde_3271	5.98e-31	113.0	28W8K@1|root,2ZI94@2|Bacteria,1P7UI@1224|Proteobacteria,433Q9@68525|delta/epsilon subdivisions,2WXNP@28221|Deltaproteobacteria,2MD62@213115|Desulfovibrionales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_5208_5	207559.Dde_3267	1.03e-193	545.0	COG1454@1|root,COG1454@2|Bacteria,1MVPH@1224|Proteobacteria,42S48@68525|delta/epsilon subdivisions,2WU1F@28221|Deltaproteobacteria,2M8P9@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	alcohol dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Fe-ADH
k141_5208_6	526222.Desal_0481	4.26e-234	654.0	COG4656@1|root,COG4656@2|Bacteria,1PJE1@1224|Proteobacteria,42P69@68525|delta/epsilon subdivisions,2WIM9@28221|Deltaproteobacteria,2M9JQ@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	RnfC Barrel sandwich hybrid domain	-	-	-	-	-	-	-	-	-	-	-	-	Complex1_51K,Fer4_17,RnfC_N,SLBB
k141_5208_7	526222.Desal_0482	5.53e-68	210.0	COG4577@1|root,COG4577@2|Bacteria,1R55P@1224|Proteobacteria,42RUF@68525|delta/epsilon subdivisions,2WNT1@28221|Deltaproteobacteria,2MB2A@213115|Desulfovibrionales	28221|Deltaproteobacteria	CQ	BMC	-	-	-	-	-	-	-	-	-	-	-	-	BMC
k141_2249_1	1238450.VIBNISOn1_50001	2.17e-94	296.0	COG1199@1|root,COG1199@2|Bacteria,1MVCU@1224|Proteobacteria,1RMNX@1236|Gammaproteobacteria,1XSN4@135623|Vibrionales	135623|Vibrionales	KL	COG1199 Rad3-related DNA helicases	dinG	-	3.6.4.12	ko:K03722	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD_2,Helicase_C_2,ResIII
k141_2519_1	864051.BurJ1DRAFT_1161	3.41e-31	122.0	COG2853@1|root,COG2853@2|Bacteria,1MVX0@1224|Proteobacteria,2VQ97@28216|Betaproteobacteria,1KM03@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	MlaA lipoprotein	vacJ	-	-	ko:K04754	-	-	-	-	ko00000	-	-	-	MlaA
k141_4248_2	1454202.PPBDW_100275___1	1.87e-75	243.0	COG2215@1|root,COG2215@2|Bacteria,1MWIW@1224|Proteobacteria,1RQ9T@1236|Gammaproteobacteria,1XWM6@135623|Vibrionales	135623|Vibrionales	P	Belongs to the NiCoT transporter (TC 2.A.52) family	-	-	-	ko:K08970	-	-	-	-	ko00000,ko02000	2.A.52.2	-	-	NicO
k141_4248_3	298386.PBPRB0546	5.31e-38	134.0	COG3683@1|root,COG3683@2|Bacteria,1R4QA@1224|Proteobacteria,1RQ73@1236|Gammaproteobacteria,1XV9U@135623|Vibrionales	135623|Vibrionales	S	transport system periplasmic component	-	-	-	ko:K06925	-	-	-	-	ko00000,ko03016	-	-	-	DUF1007
k141_4248_4	1249634.D781_1046	4.81e-142	408.0	COG0803@1|root,COG0803@2|Bacteria,1MVW9@1224|Proteobacteria,1RRM3@1236|Gammaproteobacteria,402CW@613|Serratia	1236|Gammaproteobacteria	P	Belongs to the bacterial solute-binding protein 9 family	mntA	-	-	ko:K02077,ko:K11604	ko02010,map02010	M00244,M00317	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15,3.A.1.15.7,3.A.1.15.9	-	-	ZnuA
k141_4248_5	1219072.VHA01S_017_00070	1.38e-129	376.0	COG1108@1|root,COG1108@2|Bacteria,1MVC2@1224|Proteobacteria,1RRX3@1236|Gammaproteobacteria,1Y2MR@135623|Vibrionales	135623|Vibrionales	P	ABC 3 transport family	-	-	-	ko:K02075	-	M00244	-	-	ko00000,ko00002,ko02000	3.A.1.15	-	-	ABC-3
k141_4248_6	186490.IM45_250	5.78e-63	205.0	COG1121@1|root,COG1121@2|Bacteria,1MW47@1224|Proteobacteria,1S1N4@1236|Gammaproteobacteria,1JA20@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	P	ABC transporter	mntB	-	-	ko:K02074	-	M00244	-	-	ko00000,ko00002,ko02000	3.A.1.15	-	-	ABC_tran
k141_4248_7	345073.VC395_0240	3.34e-28	105.0	COG2862@1|root,COG2862@2|Bacteria,1RANN@1224|Proteobacteria,1S2DE@1236|Gammaproteobacteria,1XWHE@135623|Vibrionales	135623|Vibrionales	S	Uncharacterized protein family, UPF0114	-	-	-	-	-	-	-	-	-	-	-	-	UPF0114
k141_3615_1	1121403.AUCV01000061_gene3747	1.04e-17	82.4	COG1073@1|root,COG1073@2|Bacteria,1RAMZ@1224|Proteobacteria	1224|Proteobacteria	S	alpha beta	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S9
k141_3615_2	335543.Sfum_2340	1.69e-71	220.0	COG2077@1|root,COG2077@2|Bacteria,1RAJ9@1224|Proteobacteria,42RE8@68525|delta/epsilon subdivisions,2WNA5@28221|Deltaproteobacteria,2MRKA@213462|Syntrophobacterales	28221|Deltaproteobacteria	O	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides	tpx	-	1.11.1.15	ko:K11065	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA,Redoxin
k141_3615_3	1304885.AUEY01000074_gene581	1.58e-179	502.0	COG0543@1|root,COG0543@2|Bacteria,1R6QZ@1224|Proteobacteria,42MVW@68525|delta/epsilon subdivisions,2WKKC@28221|Deltaproteobacteria,2MJAK@213118|Desulfobacterales	28221|Deltaproteobacteria	CH	Oxidoreductase FAD-binding domain	hdrF	-	-	-	-	-	-	-	-	-	-	-	DHODB_Fe-S_bind,FAD_binding_6,NAD_binding_1
k141_3615_4	933262.AXAM01000017_gene3141	1.75e-149	432.0	COG1150@1|root,COG1150@2|Bacteria,1QWNB@1224|Proteobacteria,43BTA@68525|delta/epsilon subdivisions,2X741@28221|Deltaproteobacteria,2MI1V@213118|Desulfobacterales	28221|Deltaproteobacteria	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_22
k141_3615_5	1304885.AUEY01000100_gene2605	1.23e-150	432.0	COG1035@1|root,COG1139@1|root,COG1035@2|Bacteria,COG1139@2|Bacteria,1NQN7@1224|Proteobacteria,42MGI@68525|delta/epsilon subdivisions,2WKNC@28221|Deltaproteobacteria,2MIJN@213118|Desulfobacterales	28221|Deltaproteobacteria	C	4Fe-4S ferredoxin iron-sulfur binding domain protein	hdrD	-	-	-	-	-	-	-	-	-	-	-	Fer4_10,Fer4_17,Fer4_8,FlpD,FrhB_FdhB_C
k141_577_1	1121441.AUCX01000002_gene2841	6.04e-129	427.0	COG1020@1|root,COG3321@1|root,COG1020@2|Bacteria,COG3321@2|Bacteria,1QK4F@1224|Proteobacteria,42NH4@68525|delta/epsilon subdivisions,2WNBU@28221|Deltaproteobacteria,2M8AN@213115|Desulfovibrionales	28221|Deltaproteobacteria	Q	TIGRFAM Amino acid adenylation	-	-	-	ko:K13611	-	-	-	-	ko00000,ko01004,ko01008	-	-	-	AMP-binding,AMP-binding_C,Acyl_transf_1,Condensation,KAsynt_C_assoc,Ketoacyl-synt_C,Methyltransf_12,PP-binding,Thioesterase,ketoacyl-synt
k141_811_1	177439.DP2081	5.51e-108	329.0	COG1816@1|root,COG1816@2|Bacteria,1R6Q8@1224|Proteobacteria,42SWZ@68525|delta/epsilon subdivisions,2WPSC@28221|Deltaproteobacteria,2MMF7@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Adenosine/AMP deaminase	-	-	3.5.4.4	ko:K01488	ko00230,ko01100,ko05340,map00230,map01100,map05340	-	R01560,R02556	RC00477	ko00000,ko00001,ko01000	-	-	-	A_deaminase
k141_3616_1	103690.17131310	8.52e-38	134.0	COG3627@1|root,COG3627@2|Bacteria,1G3KN@1117|Cyanobacteria,1HKEG@1161|Nostocales	1117|Cyanobacteria	P	PFAM Phosphonate metabolism protein PhnJ	phnJ	-	4.7.1.1	ko:K06163	ko00440,map00440	-	R10204	RC03078,RC03079	ko00000,ko00001,ko01000	-	-	-	PhnJ
k141_3616_2	1187848.AJYQ01000077_gene1780	1.42e-92	282.0	COG4107@1|root,COG4107@2|Bacteria,1MVRN@1224|Proteobacteria,1RR70@1236|Gammaproteobacteria,1XUAD@135623|Vibrionales	135623|Vibrionales	P	ATPases associated with a variety of cellular activities	phnK	-	-	ko:K05781	-	-	-	-	ko00000	-	-	-	ABC_tran
k141_3616_3	1123228.AUIH01000006_gene2165	0.000232	46.2	COG4175@1|root,COG4175@2|Bacteria,1MU86@1224|Proteobacteria,1RY4K@1236|Gammaproteobacteria,1XHHR@135619|Oceanospirillales	135619|Oceanospirillales	E	ABC transporter	-	-	3.6.3.32	ko:K02000	ko02010,map02010	M00208	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.12	-	-	ABC_tran
k141_1252_1	945550.VISI1226_20250	2.03e-183	528.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,1RPES@1236|Gammaproteobacteria,1XU1H@135623|Vibrionales	135623|Vibrionales	S	COG0488 ATPase components of ABC transporters with duplicated ATPase domains	yheS	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn,CENP-O
k141_1252_2	55601.VANGNB10_cI2361	1.67e-57	183.0	COG5589@1|root,COG5589@2|Bacteria,1NGHI@1224|Proteobacteria,1SGFT@1236|Gammaproteobacteria,1XT79@135623|Vibrionales	135623|Vibrionales	S	Protein of unknown function (DUF2390)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2390
k141_1252_3	511062.GU3_05190	1.3e-17	76.3	COG3089@1|root,COG3089@2|Bacteria,1N6TM@1224|Proteobacteria,1SCDE@1236|Gammaproteobacteria,1Y4UZ@135624|Aeromonadales	135624|Aeromonadales	S	Belongs to the UPF0270 family	-	-	-	ko:K09898	-	-	-	-	ko00000	-	-	-	UPF0270
k141_1252_4	675816.VIA_000453	5.28e-202	560.0	COG3954@1|root,COG3954@2|Bacteria,1MWN9@1224|Proteobacteria,1RMS7@1236|Gammaproteobacteria,1XSST@135623|Vibrionales	135623|Vibrionales	G	Phosphoribulokinase	prkB	-	2.7.1.19	ko:K00855	ko00710,ko01100,ko01120,ko01200,map00710,map01100,map01120,map01200	M00165,M00166	R01523	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PRK
k141_1252_5	316275.VSAL_I2737	5.08e-147	414.0	COG0664@1|root,COG0664@2|Bacteria,1MXID@1224|Proteobacteria,1RMIZ@1236|Gammaproteobacteria,1XT4N@135623|Vibrionales	135623|Vibrionales	K	COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases	crp	-	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	Crp,cNMP_binding
k141_1252_6	1280001.BAOA01000039_gene2503	1.23e-118	347.0	COG5383@1|root,COG5383@2|Bacteria,1MWTV@1224|Proteobacteria,1RNJF@1236|Gammaproteobacteria,1XTHF@135623|Vibrionales	135623|Vibrionales	S	DUF1338	-	-	-	-	-	-	-	-	-	-	-	-	DUF1338
k141_1252_7	754436.JCM19237_4947	2.26e-28	112.0	COG1012@1|root,COG1012@2|Bacteria,1MV2I@1224|Proteobacteria,1RPQW@1236|Gammaproteobacteria,1XTD0@135623|Vibrionales	135623|Vibrionales	C	Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate	astD	GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016491,GO:0016620,GO:0016903,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0055114,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	1.2.1.71	ko:K06447	ko00330,ko01100,map00330,map01100	-	R05049	RC00080	ko00000,ko00001,ko01000	-	-	-	Aldedh
k141_812_1	591001.Acfer_1595	7.02e-08	54.7	COG0340@1|root,COG1654@1|root,COG0340@2|Bacteria,COG1654@2|Bacteria,1TQCU@1239|Firmicutes,4H1W3@909932|Negativicutes	909932|Negativicutes	HK	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor	birA	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_C,BPL_LplA_LipB,HTH_11
k141_812_2	1121396.KB893065_gene1641	1.1e-48	163.0	COG1268@1|root,COG1268@2|Bacteria,1RH78@1224|Proteobacteria,42RTB@68525|delta/epsilon subdivisions,2WNS7@28221|Deltaproteobacteria,2MK04@213118|Desulfobacterales	28221|Deltaproteobacteria	S	BioY family	-	-	-	ko:K03523	ko02010,map02010	M00581,M00582	-	-	ko00000,ko00001,ko00002,ko02000	2.A.88.1,2.A.88.2	-	-	BioY
k141_812_3	1121405.dsmv_0672	2.64e-49	166.0	COG1122@1|root,COG1122@2|Bacteria,1N5X0@1224|Proteobacteria,42QY8@68525|delta/epsilon subdivisions,2WMQU@28221|Deltaproteobacteria,2MJHT@213118|Desulfobacterales	28221|Deltaproteobacteria	P	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K16784	ko02010,map02010	M00581	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25.1	-	-	ABC_tran
k141_285_1	1515746.HR45_08650	8.81e-94	298.0	COG2199@1|root,COG2199@2|Bacteria,1R4JZ@1224|Proteobacteria,1RW5E@1236|Gammaproteobacteria,2QAQ5@267890|Shewanellaceae	1236|Gammaproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS,PAS_8
k141_285_2	1515746.HR45_08645	2.74e-43	146.0	COG0226@1|root,COG0226@2|Bacteria,1N7RX@1224|Proteobacteria,1SCQW@1236|Gammaproteobacteria,2QCXV@267890|Shewanellaceae	1236|Gammaproteobacteria	P	ABC-type phosphate transport system, periplasmic component	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_285_3	1056512.D515_00301	3.25e-54	191.0	COG3203@1|root,COG3203@2|Bacteria,1RE61@1224|Proteobacteria,1S5G1@1236|Gammaproteobacteria,1Y28K@135623|Vibrionales	135623|Vibrionales	M	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	Porin_4
k141_285_5	314292.VAS14_18946	6.09e-57	177.0	COG0234@1|root,COG0234@2|Bacteria,1MZ2X@1224|Proteobacteria,1S8YR@1236|Gammaproteobacteria,1XXUS@135623|Vibrionales	135623|Vibrionales	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
k141_285_6	617140.AJZE01000045_gene1348	7.75e-92	274.0	COG2345@1|root,COG2345@2|Bacteria,1RDXT@1224|Proteobacteria,1S4DW@1236|Gammaproteobacteria,1XTKY@135623|Vibrionales	135623|Vibrionales	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_11,HTH_24,HTH_DeoR
k141_285_7	55601.VANGNB10_cI2417	1.36e-34	122.0	2EM8V@1|root,33EY0@2|Bacteria,1NBBF@1224|Proteobacteria,1SDDM@1236|Gammaproteobacteria,1XYUC@135623|Vibrionales	135623|Vibrionales	S	Protein of unknown function (DUF3135)	VV3022	-	-	-	-	-	-	-	-	-	-	-	DUF3135
k141_285_8	701176.VIBRN418_13983	1.4e-37	130.0	COG3232@1|root,COG3232@2|Bacteria,1N7P5@1224|Proteobacteria,1S5D7@1236|Gammaproteobacteria,1XXDP@135623|Vibrionales	135623|Vibrionales	G	5-carboxymethyl-2-hydroxymuconate isomerase	hpcD	-	5.3.3.10	ko:K01826	ko00350,ko01120,ko01220,map00350,map01120,map01220	M00533	R04379,R04482	RC01141,RC01162	ko00000,ko00001,ko00002,ko01000	-	-	-	CHMI
k141_285_9	945550.VISI1226_10499	3.44e-149	423.0	COG0149@1|root,COG0149@2|Bacteria,1MWK5@1224|Proteobacteria,1RM8I@1236|Gammaproteobacteria,1XUEE@135623|Vibrionales	135623|Vibrionales	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
k141_285_10	1187848.AJYQ01000103_gene1067	2.35e-211	597.0	COG0534@1|root,COG0534@2|Bacteria,1MVRV@1224|Proteobacteria,1RRDQ@1236|Gammaproteobacteria,1XTD2@135623|Vibrionales	135623|Vibrionales	V	Na driven multidrug efflux pump	-	-	-	-	-	-	-	-	-	-	-	-	MatE
k141_285_12	1051646.VITU9109_02432	2.43e-153	438.0	COG1575@1|root,COG1575@2|Bacteria,1MXQQ@1224|Proteobacteria,1RPW5@1236|Gammaproteobacteria,1XUCP@135623|Vibrionales	135623|Vibrionales	H	Belongs to the MenA family. Type 1 subfamily	menA	-	2.5.1.74	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R05617,R06858,R10757	RC02935,RC02936,RC03264	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
k141_3617_1	1265505.ATUG01000003_gene832	1.91e-47	165.0	COG0614@1|root,COG0614@2|Bacteria,1PGUA@1224|Proteobacteria,42PAA@68525|delta/epsilon subdivisions,2WNB5@28221|Deltaproteobacteria,2MQ0P@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Periplasmic binding protein	-	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
k141_813_1	574375.BAGA_29320	2.52e-16	78.2	COG1443@1|root,COG1443@2|Bacteria,1V6SB@1239|Firmicutes,4HJ2T@91061|Bacilli,1ZFNY@1386|Bacillus	91061|Bacilli	I	COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes	M1-740	-	-	-	-	-	-	-	-	-	-	-	NUDIX
k141_1253_1	411464.DESPIG_02923	3.94e-117	349.0	COG0677@1|root,COG0677@2|Bacteria,1MUC6@1224|Proteobacteria,42M4F@68525|delta/epsilon subdivisions,2WJEW@28221|Deltaproteobacteria,2M7SQ@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	capL	-	1.1.1.136	ko:K02474,ko:K13015	ko00520,map00520	-	R00421,R06894	RC00291	ko00000,ko00001,ko01000,ko01005	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
k141_579_1	93220.LV28_09340	4.14e-73	229.0	COG0388@1|root,COG0388@2|Bacteria,1MUUB@1224|Proteobacteria,2VIR4@28216|Betaproteobacteria,1K2WY@119060|Burkholderiaceae	28216|Betaproteobacteria	S	PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	opaA	-	3.5.5.1	ko:K01501,ko:K11206	ko00380,ko00460,ko00627,ko00643,ko00910,ko01120,map00380,map00460,map00627,map00643,map00910,map01120	-	R00540,R01887,R03093,R03542,R05591,R07855	RC00315,RC00325,RC00617,RC00959,RC02811	ko00000,ko00001,ko01000	-	-	-	CN_hydrolase
k141_579_2	1348635.BBJY01000007_gene237	1.23e-181	511.0	COG3940@1|root,COG3940@2|Bacteria,1NKF0@1224|Proteobacteria,1RNIH@1236|Gammaproteobacteria,1XWTM@135623|Vibrionales	1236|Gammaproteobacteria	G	Glycosyl hydrolases family 43	abf2	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_43
k141_579_3	1348635.BBJY01000007_gene236	2.08e-39	140.0	COG1609@1|root,COG1609@2|Bacteria,1R7GP@1224|Proteobacteria,1RQ7P@1236|Gammaproteobacteria,1XV5G@135623|Vibrionales	135623|Vibrionales	K	Bacterial regulatory proteins, lacI family	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
k141_816_1	637905.SVI_3766	1.23e-10	67.0	COG3049@1|root,COG3049@2|Bacteria,1MWPQ@1224|Proteobacteria,1SZSI@1236|Gammaproteobacteria,2QCNW@267890|Shewanellaceae	1236|Gammaproteobacteria	M	Linear amide C-N hydrolases, choloylglycine hydrolase family	-	-	3.5.1.24	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	-	R02797,R03975,R03977,R04486,R04487,R05835	RC00090,RC00096	ko00000,ko00001,ko01000	-	-	-	CBAH
k141_3618_1	1348635.BBJY01000001_gene2627	3.73e-232	646.0	COG0160@1|root,COG0160@2|Bacteria,1MWY6@1224|Proteobacteria,1RQKU@1236|Gammaproteobacteria,1XT3C@135623|Vibrionales	135623|Vibrionales	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	ectB	GO:0003674,GO:0003824,GO:0006082,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0018130,GO:0019491,GO:0019752,GO:0032787,GO:0042399,GO:0043436,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.6.1.76	ko:K00836	ko00260,ko01100,ko01120,ko01210,ko01230,map00260,map01100,map01120,map01210,map01230	M00033	R06977	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
k141_4251_1	701176.VIBRN418_09718	5.14e-55	178.0	COG2249@1|root,COG2249@2|Bacteria,1PCH7@1224|Proteobacteria,1SXI5@1236|Gammaproteobacteria,1XZM8@135623|Vibrionales	135623|Vibrionales	S	NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	Flavodoxin_2
k141_4251_2	177437.HRM2_07860	3.43e-28	123.0	COG0840@1|root,COG4191@1|root,COG0840@2|Bacteria,COG4191@2|Bacteria,1MU9B@1224|Proteobacteria,42MBK@68525|delta/epsilon subdivisions,2WKDV@28221|Deltaproteobacteria,2MINH@213118|Desulfobacterales	28221|Deltaproteobacteria	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal,dCache_1
k141_1925_4	672.VV93_v1c25150	9.19e-51	166.0	COG2137@1|root,COG2137@2|Bacteria,1N6P6@1224|Proteobacteria,1SCMF@1236|Gammaproteobacteria,1XWKA@135623|Vibrionales	135623|Vibrionales	S	Modulates RecA activity	recX	GO:0006282,GO:0008150,GO:0019219,GO:0019222,GO:0031323,GO:0048583,GO:0050789,GO:0050794,GO:0051052,GO:0051171,GO:0060255,GO:0065007,GO:0080090,GO:0080134,GO:0080135,GO:2001020	-	ko:K03565	-	-	-	-	ko00000,ko03400	-	-	-	RecX
k141_1925_6	945543.VIBR0546_19387	7.66e-62	195.0	COG1546@1|root,COG1546@2|Bacteria,1RH2Y@1224|Proteobacteria,1S5WH@1236|Gammaproteobacteria,1XXEF@135623|Vibrionales	135623|Vibrionales	S	Belongs to the CinA family	-	-	3.5.1.42	ko:K03743	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA
k141_1925_7	675816.VIA_003978	0.0	1383.0	COG0249@1|root,COG0249@2|Bacteria,1MUGX@1224|Proteobacteria,1RNW3@1236|Gammaproteobacteria,1XTI0@135623|Vibrionales	135623|Vibrionales	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	mutS	GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
k141_3619_1	1265505.ATUG01000003_gene754	2.51e-28	107.0	COG1845@1|root,COG1845@2|Bacteria,1MUCK@1224|Proteobacteria,42RCU@68525|delta/epsilon subdivisions,2WN7W@28221|Deltaproteobacteria,2MJQT@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Cytochrome c oxidase subunit III	-	-	1.9.3.1	ko:K02276,ko:K02299	ko00190,ko01100,map00190,map01100	M00155,M00417	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.5,3.D.4.6	-	-	COX3
k141_3619_2	1265505.ATUG01000003_gene753	3.57e-38	141.0	COG0843@1|root,COG0843@2|Bacteria,1MU7S@1224|Proteobacteria,42M18@68525|delta/epsilon subdivisions,2WJUK@28221|Deltaproteobacteria,2MHW9@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Cytochrome C and Quinol oxidase polypeptide I	coxA	-	1.10.3.10,1.9.3.1	ko:K02274,ko:K02298	ko00190,ko01100,map00190,map01100	M00155,M00417	R00081,R11335	RC00016,RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.5,3.D.4.6	-	-	COX1
k141_5210_2	1265756.AWZW01000008_gene1408	3.02e-98	308.0	COG0845@1|root,COG0845@2|Bacteria,1N97Q@1224|Proteobacteria,2U1HJ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	Evidence 4 Homologs of previously reported genes of	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_3
k141_5210_3	1121289.JHVL01000026_gene189	0.0	881.0	COG1001@1|root,COG1001@2|Bacteria,1TP84@1239|Firmicutes,247KN@186801|Clostridia,36DDA@31979|Clostridiaceae	186801|Clostridia	F	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family	ade	-	3.5.4.2	ko:K01486	ko00230,ko01100,map00230,map01100	-	R01244	RC00477	ko00000,ko00001,ko01000	-	-	-	Adenine_deam_C,Amidohydro_1
k141_1926_1	177439.DP0362	1.49e-32	113.0	COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,42V0K@68525|delta/epsilon subdivisions,2WR92@28221|Deltaproteobacteria,2MKYU@213118|Desulfobacterales	28221|Deltaproteobacteria	K	PFAM Cold-shock	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
k141_287_1	767817.Desgi_2847	2.17e-86	278.0	COG2274@1|root,COG2274@2|Bacteria,1V77J@1239|Firmicutes,25E7C@186801|Clostridia,261EJ@186807|Peptococcaceae	186801|Clostridia	V	NHLM bacteriocin system ABC transporter, peptidase ATP-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC_membrane,ABC_tran,Peptidase_C39
k141_287_2	313606.M23134_03799	4.01e-55	195.0	COG0845@1|root,COG0845@2|Bacteria,4NKUY@976|Bacteroidetes,47V1B@768503|Cytophagia	976|Bacteroidetes	M	Biotin-lipoyl like	-	-	-	ko:K02022	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3
k141_287_3	760154.Sulba_0754	4.28e-46	160.0	COG2890@1|root,COG2890@2|Bacteria	2|Bacteria	J	protein-(glutamine-N5) methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	MTS
k141_2841_58	1443125.Z962_06870	1.93e-127	372.0	COG0583@1|root,COG0583@2|Bacteria,1TTB2@1239|Firmicutes,24CIK@186801|Clostridia,36GEG@31979|Clostridiaceae	186801|Clostridia	K	LysR family	-	-	-	ko:K21755	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,LysR_substrate
k141_2841_59	386415.NT01CX_0308	1.18e-312	863.0	COG0446@1|root,COG0607@1|root,COG0446@2|Bacteria,COG0607@2|Bacteria,1TPWW@1239|Firmicutes,2484C@186801|Clostridia,36DJA@31979|Clostridiaceae	186801|Clostridia	P	Belongs to the sulfur carrier protein TusA family	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Pyr_redox_dim,Rhodanese
k141_2841_60	386415.NT01CX_0307	1.42e-224	628.0	COG2391@1|root,COG2391@2|Bacteria,1TSNG@1239|Firmicutes,25DZC@186801|Clostridia,36FZZ@31979|Clostridiaceae	186801|Clostridia	S	Sulphur transport	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
k141_2841_61	1453501.JELR01000002_gene723	1.02e-19	87.0	29R72@1|root,30C8E@2|Bacteria,1RE0P@1224|Proteobacteria,1S53D@1236|Gammaproteobacteria,46AQE@72275|Alteromonadaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_2841_62	1511.CLOST_0374	1.7e-113	330.0	COG0664@1|root,COG0664@2|Bacteria,1V5GJ@1239|Firmicutes,24GKP@186801|Clostridia,25U8N@186804|Peptostreptococcaceae	186801|Clostridia	K	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Crp_2,cNMP_binding
k141_2841_63	1511.CLOST_0375	7.14e-177	500.0	COG1744@1|root,COG1744@2|Bacteria,1TPEU@1239|Firmicutes,248QT@186801|Clostridia,25S1Q@186804|Peptostreptococcaceae	186801|Clostridia	S	ABC transporter substrate-binding protein PnrA-like	-	-	-	ko:K07335	-	-	-	-	ko00000	-	-	-	Bmp
k141_2841_64	1511.CLOST_0376	4.19e-283	783.0	COG3845@1|root,COG3845@2|Bacteria,1UYQA@1239|Firmicutes,24XN8@186801|Clostridia,25QC2@186804|Peptostreptococcaceae	186801|Clostridia	S	ABC transporter	-	-	3.6.3.17	ko:K02056	-	M00221	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.2	-	-	ABC_tran
k141_2841_65	1511.CLOST_0377	4e-192	540.0	COG4603@1|root,COG4603@2|Bacteria,1TP1F@1239|Firmicutes,2494C@186801|Clostridia,25QBZ@186804|Peptostreptococcaceae	186801|Clostridia	S	Branched-chain amino acid transport system / permease component	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
k141_2841_66	1121324.CLIT_11c00180	2.55e-143	412.0	COG1079@1|root,COG1079@2|Bacteria,1TP8Y@1239|Firmicutes,2486N@186801|Clostridia,25R77@186804|Peptostreptococcaceae	186801|Clostridia	S	Branched-chain amino acid transport system / permease component	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
k141_2841_67	1511.CLOST_0380	2.75e-175	504.0	COG1249@1|root,COG1249@2|Bacteria,1TP1W@1239|Firmicutes,249R3@186801|Clostridia,25RJ2@186804|Peptostreptococcaceae	186801|Clostridia	C	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain	-	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
k141_2841_68	1511.CLOST_0381	4.44e-120	349.0	COG2820@1|root,COG2820@2|Bacteria,1TSEU@1239|Firmicutes,25E2U@186801|Clostridia,25TE3@186804|Peptostreptococcaceae	186801|Clostridia	F	Phosphorylase superfamily	-	-	2.4.2.3	ko:K00757	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01876,R02484,R08229	RC00063	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
k141_2841_69	1321778.HMPREF1982_01537	9.64e-47	166.0	COG1396@1|root,COG5012@1|root,COG1396@2|Bacteria,COG5012@2|Bacteria,1V5B3@1239|Firmicutes,25BRN@186801|Clostridia	186801|Clostridia	K	B12 binding domain	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,B12-binding_2,HTH_3
k141_2841_70	373903.Hore_07490	1.69e-53	175.0	COG4250@1|root,COG4250@2|Bacteria,1V5NN@1239|Firmicutes,24I62@186801|Clostridia,3WBME@53433|Halanaerobiales	186801|Clostridia	T	Sensory domain in DIguanylate Cyclases and Two-component system	-	-	-	-	-	-	-	-	-	-	-	-	DICT
k141_2841_71	397290.C810_03943	4.21e-10	64.7	COG3601@1|root,COG3601@2|Bacteria,1V4BW@1239|Firmicutes,24E4V@186801|Clostridia,27KK4@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins	ribU	-	-	-	-	-	-	-	-	-	-	-	ECF_trnsprt
k141_1631_3	1304885.AUEY01000108_gene2927	4.65e-66	216.0	COG0491@1|root,COG0491@2|Bacteria	2|Bacteria	GM	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
k141_4362_1	1304885.AUEY01000002_gene347	5.17e-243	681.0	COG3604@1|root,COG3604@2|Bacteria,1QTT3@1224|Proteobacteria,42Y69@68525|delta/epsilon subdivisions,2WJ5F@28221|Deltaproteobacteria,2MI66@213118|Desulfobacterales	28221|Deltaproteobacteria	KT	PFAM sigma-54 factor interaction domain-containing protein	-	-	-	ko:K02584	ko02020,map02020	-	-	-	ko00000,ko00001,ko03000	-	-	-	GAF,GAF_2,HTH_8,Sigma54_activat
k141_4362_2	1304885.AUEY01000001_gene3295	7.01e-54	203.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42RBF@68525|delta/epsilon subdivisions,2WN2X@28221|Deltaproteobacteria,2MMQU@213118|Desulfobacterales	28221|Deltaproteobacteria	NT	Cache domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,MCPsignal,dCache_1
k141_4362_3	1379270.AUXF01000001_gene2317	3.76e-20	102.0	COG0840@1|root,COG0840@2|Bacteria,1ZUPA@142182|Gemmatimonadetes	142182|Gemmatimonadetes	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal
k141_2969_2	1304885.AUEY01000009_gene1933	1.24e-151	446.0	COG0621@1|root,COG0621@2|Bacteria,1MURS@1224|Proteobacteria,42MQ3@68525|delta/epsilon subdivisions,2WJEE@28221|Deltaproteobacteria,2MHM5@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
k141_2969_3	933262.AXAM01000029_gene2735	2.24e-55	179.0	COG1259@1|root,COG1259@2|Bacteria,1RFFV@1224|Proteobacteria,42SCI@68525|delta/epsilon subdivisions,2WPWT@28221|Deltaproteobacteria,2MJT1@213118|Desulfobacterales	28221|Deltaproteobacteria	O	Bifunctional nuclease	-	-	-	ko:K08999	-	-	-	-	ko00000	-	-	-	DNase-RNase
k141_1633_1	1190603.AJYD01000021_gene134	3.18e-33	116.0	COG0724@1|root,COG0724@2|Bacteria,1N6VR@1224|Proteobacteria,1SCKA@1236|Gammaproteobacteria,1XZ1Z@135623|Vibrionales	135623|Vibrionales	S	RNA recognition motif	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
k141_1633_2	314292.VAS14_18644	9.71e-39	139.0	COG3637@1|root,COG3637@2|Bacteria,1R3QN@1224|Proteobacteria,1RY3J@1236|Gammaproteobacteria,1XUQF@135623|Vibrionales	135623|Vibrionales	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	SO3905	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl
k141_1633_3	981223.AIED01000025_gene1467	4.06e-17	79.0	COG3631@1|root,COG3631@2|Bacteria,1RHRD@1224|Proteobacteria,1T28C@1236|Gammaproteobacteria,3NN61@468|Moraxellaceae	1236|Gammaproteobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
k141_4062_1	1116375.VEJY3_21381	7.94e-118	348.0	COG2390@1|root,COG2390@2|Bacteria,1MWHQ@1224|Proteobacteria,1RRDZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	transcriptional regulator	lsrR_2	-	-	-	-	-	-	-	-	-	-	-	HTH_23,Sigma70_r4_2,Sugar-bind
k141_4062_2	1151292.QEW_1119	2e-44	149.0	COG1683@1|root,COG1683@2|Bacteria,1V700@1239|Firmicutes,24JD2@186801|Clostridia,25RKG@186804|Peptostreptococcaceae	186801|Clostridia	S	Protein of unknown function (DUF523)	-	-	-	-	-	-	-	-	-	-	-	-	DUF523
k141_4062_3	425104.Ssed_2903	1.27e-39	140.0	COG0350@1|root,COG0350@2|Bacteria,1N2YQ@1224|Proteobacteria,1S68H@1236|Gammaproteobacteria,2QC61@267890|Shewanellaceae	1236|Gammaproteobacteria	H	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated	ogt	-	2.1.1.63	ko:K00567	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_binding_1,Methyltransf_1N
k141_4062_4	1005994.GTGU_03495	5.36e-71	223.0	COG1309@1|root,COG1309@2|Bacteria,1NDME@1224|Proteobacteria,1RQQB@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	Transcriptional regulator	ybiH	GO:0003674,GO:0003700,GO:0005488,GO:0005515,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031333,GO:0031334,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0042802,GO:0043170,GO:0043254,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0046483,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051130,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901576,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2000144,GO:2001141	-	-	-	-	-	-	-	-	-	-	DUF1956,TetR_N
k141_4062_5	399742.Ent638_1286	9.26e-131	383.0	COG0845@1|root,COG0845@2|Bacteria,1MUG6@1224|Proteobacteria,1RP16@1236|Gammaproteobacteria,3X0MJ@547|Enterobacter	1236|Gammaproteobacteria	M	PFAM secretion protein HlyD	ybhG	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0042221,GO:0044464,GO:0046677,GO:0050896,GO:0071944	-	ko:K01993	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
k141_4062_6	1224136.AMFN01000002_gene334	5.8e-303	840.0	COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,1RMM4@1236|Gammaproteobacteria	1236|Gammaproteobacteria	V	(ABC) transporter	ybhF	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006855,GO:0008150,GO:0015562,GO:0015893,GO:0016020,GO:0022857,GO:0042221,GO:0042493,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071944	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
k141_4062_7	500640.CIT292_08018	2.27e-187	530.0	COG0842@1|root,COG0842@2|Bacteria,1MW5R@1224|Proteobacteria,1RPB4@1236|Gammaproteobacteria,3WWNI@544|Citrobacter	1236|Gammaproteobacteria	V	ABC-2 family transporter protein	ybhS	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006855,GO:0008150,GO:0015562,GO:0015893,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0042221,GO:0042493,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071944	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC2_membrane_3
k141_4062_8	7213.XP_004528174.1	3.68e-173	493.0	COG1131@1|root,KOG0059@2759|Eukaryota	2759|Eukaryota	V	ATPase activity, coupled to transmembrane movement of substances	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_3,ABC_tran
k141_4062_9	1283284.AZUK01000001_gene505	4.17e-181	514.0	COG1820@1|root,COG1820@2|Bacteria,1MW8Y@1224|Proteobacteria,1RMRV@1236|Gammaproteobacteria,1Y3SZ@135624|Aeromonadales	135624|Aeromonadales	G	Belongs to the metallo-dependent hydrolases superfamily. NagA family	nagA	-	3.5.1.25	ko:K01443	ko00520,ko01130,map00520,map01130	-	R02059	RC00166,RC00300	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
k141_4062_11	1283284.AZUK01000001_gene503	3.31e-265	738.0	COG1263@1|root,COG1264@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,1MY1V@1224|Proteobacteria,1RMYZ@1236|Gammaproteobacteria,1Y3SR@135624|Aeromonadales	135624|Aeromonadales	G	PTS system, N-acetylglucosamine-specific	nagE	-	2.7.1.193	ko:K02803,ko:K02804	ko00520,ko02060,map00520,map02060	M00267	R05199	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.1.1.15,4.A.1.1.2,4.A.1.1.5,4.A.1.1.7	-	-	PTS_EIIB,PTS_EIIC
k141_4062_12	1304885.AUEY01000001_gene3209	3.87e-99	297.0	COG0682@1|root,COG0682@2|Bacteria,1MVE3@1224|Proteobacteria,42M2I@68525|delta/epsilon subdivisions,2WMSH@28221|Deltaproteobacteria,2MPU8@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
k141_4062_14	1348635.BBJY01000001_gene2598	1.06e-162	465.0	28HJP@1|root,2Z7UT@2|Bacteria,1MWM4@1224|Proteobacteria,1RQNG@1236|Gammaproteobacteria,1XUX1@135623|Vibrionales	135623|Vibrionales	S	of the major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DUF2955,FUSC_2
k141_4062_15	1348635.BBJY01000001_gene2599	6.74e-153	441.0	COG1566@1|root,COG1566@2|Bacteria,1MU7I@1224|Proteobacteria,1RPV2@1236|Gammaproteobacteria,1XUFT@135623|Vibrionales	135623|Vibrionales	V	Secretion protein	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
k141_4062_16	1191299.AJYX01000097_gene1712	3.99e-57	182.0	COG1846@1|root,COG1846@2|Bacteria,1N78T@1224|Proteobacteria,1S26B@1236|Gammaproteobacteria,1XX2C@135623|Vibrionales	135623|Vibrionales	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	ko:K06075	-	-	-	-	ko00000,ko03000	-	-	-	MarR
k141_4062_17	1280001.BAOA01000007_gene3835	1.92e-99	291.0	COG0566@1|root,COG0566@2|Bacteria,1REIN@1224|Proteobacteria,1S48A@1236|Gammaproteobacteria,1XWMC@135623|Vibrionales	135623|Vibrionales	J	SpoU rRNA Methylase family	-	-	-	-	-	-	-	-	-	-	-	-	SpoU_methylase
k141_4062_18	1348635.BBJY01000003_gene3934	4.56e-194	548.0	COG2866@1|root,COG2866@2|Bacteria,1MUMN@1224|Proteobacteria,1RQB4@1236|Gammaproteobacteria,1XU40@135623|Vibrionales	135623|Vibrionales	E	Zn_pept	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
k141_4062_19	1116375.VEJY3_17246	0.0	885.0	COG1263@1|root,COG1264@1|root,COG2190@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,COG2190@2|Bacteria,1MXEG@1224|Proteobacteria,1RNEG@1236|Gammaproteobacteria,1XXHE@135623|Vibrionales	135623|Vibrionales	G	phosphotransferase system, EIIB	-	-	-	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	M00271	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.1.2.11,4.A.1.2.2,4.A.1.2.5,4.A.1.2.6	-	-	PTS_EIIA_1,PTS_EIIB,PTS_EIIC
k141_4062_20	1191299.AJYX01000097_gene1790	2.66e-277	766.0	COG2723@1|root,COG2723@2|Bacteria,1MWG6@1224|Proteobacteria,1RMM2@1236|Gammaproteobacteria,1XSV6@135623|Vibrionales	135623|Vibrionales	G	Belongs to the glycosyl hydrolase 1 family	bglA	-	3.2.1.86	ko:K01223	ko00010,ko00500,map00010,map00500	-	R00839,R05133,R05134	RC00049,RC00171,RC00714	ko00000,ko00001,ko01000	-	GT1	-	Glyco_hydro_1
k141_4062_22	1191299.AJYX01000097_gene1725	4.32e-171	483.0	COG3940@1|root,COG3940@2|Bacteria,1NKF0@1224|Proteobacteria,1RNIH@1236|Gammaproteobacteria,1XWTM@135623|Vibrionales	135623|Vibrionales	G	Glycosyl hydrolases family 43	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_43
k141_4062_23	1027273.GZ77_24625	3.1e-85	263.0	2DBB6@1|root,2Z85M@2|Bacteria,1QMDX@1224|Proteobacteria,1RZPX@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_2992_7	1517681.HW45_27530	3.08e-55	175.0	COG0690@1|root,COG0690@2|Bacteria,1RDI9@1224|Proteobacteria,1S3PA@1236|Gammaproteobacteria,1XXD8@135623|Vibrionales	135623|Vibrionales	U	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation	secE	GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705	-	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecE
k141_1004_1	29495.EA26_12820	1.07e-39	149.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,1XUI8@135623|Vibrionales	135623|Vibrionales	NT	methyl-accepting chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal,dCache_1
k141_2699_1	1469948.JPNB01000001_gene2403	9.62e-43	149.0	COG1592@1|root,COG1773@1|root,COG1592@2|Bacteria,COG1773@2|Bacteria,1VEQC@1239|Firmicutes,24QUV@186801|Clostridia,36MM3@31979|Clostridiaceae	186801|Clostridia	C	PFAM Rubredoxin-type Fe(Cys)4 protein	rub	-	1.18.1.1	ko:K05297	ko00071,map00071	-	R02000	-	ko00000,ko00001,ko01000	-	-	-	Rubredoxin
k141_1005_1	1122614.JHZF01000011_gene1327	9.66e-20	94.7	COG0500@1|root,COG0500@2|Bacteria,1QW86@1224|Proteobacteria,2TWSB@28211|Alphaproteobacteria,2PCWC@252301|Oceanicola	28211|Alphaproteobacteria	Q	Dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	Dimerisation2,Methyltransf_2
k141_2994_1	580340.Tlie_0797	1.84e-08	54.7	COG2316@1|root,COG2316@2|Bacteria,3TASC@508458|Synergistetes	508458|Synergistetes	S	TIGRFAM metal dependent phophohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HD
k141_2994_2	96561.Dole_1733	3.38e-17	82.0	COG2911@1|root,COG3391@1|root,COG5276@1|root,COG2911@2|Bacteria,COG3391@2|Bacteria,COG5276@2|Bacteria,1QW1C@1224|Proteobacteria	1224|Proteobacteria	G	Protein of unknown function (DUF1566)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1566
k141_3306_2	55601.VANGNB10_cI0862	2.4e-82	247.0	COG0250@1|root,COG0250@2|Bacteria,1N01W@1224|Proteobacteria,1S91B@1236|Gammaproteobacteria,1XX33@135623|Vibrionales	135623|Vibrionales	K	Enhances distal genes transcription elongation in a specialized subset of operons that encode extracytoplasmic components	rfaH	-	-	ko:K05785	-	-	-	-	ko00000,ko03000	-	-	-	NusG
k141_3306_3	672.VV93_v1c09270	5.79e-108	320.0	COG0276@1|root,COG0276@2|Bacteria,1MVR1@1224|Proteobacteria,1RMMS@1236|Gammaproteobacteria,1XUVQ@135623|Vibrionales	135623|Vibrionales	H	Catalyzes the ferrous insertion into protoporphyrin IX	hemH	GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.99.1.1,4.99.1.9	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R00310,R11329	RC01012	ko00000,ko00001,ko00002,ko01000	-	-	-	Ferrochelatase
k141_3306_5	983545.Glaag_3455	1.03e-63	202.0	COG3409@1|root,COG3409@2|Bacteria,1ND4S@1224|Proteobacteria,1S7MB@1236|Gammaproteobacteria,46B9D@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	Putative peptidoglycan binding domain	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_1
k141_3306_6	1128912.GMES_0153	3.25e-120	367.0	COG3291@1|root,COG3291@2|Bacteria,1QZ7K@1224|Proteobacteria,1T40V@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_3306_8	1136163.M565_ctg1P0388	2.4e-76	242.0	COG3710@1|root,COG3710@2|Bacteria,1QXRC@1224|Proteobacteria,1SDUS@1236|Gammaproteobacteria,1XUD7@135623|Vibrionales	135623|Vibrionales	K	COG3710 DNA-binding winged-HTH domains	toxR	GO:0000156,GO:0000160,GO:0003674,GO:0006355,GO:0007154,GO:0007165,GO:0008150,GO:0009405,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0023052,GO:0031323,GO:0031326,GO:0035556,GO:0044419,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0051704,GO:0051716,GO:0060089,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141	-	ko:K10921	ko05111,map05111	-	-	-	ko00000,ko00001	-	-	-	Trans_reg_C
k141_3306_9	243277.VC_0983	7.86e-26	100.0	2AVZE@1|root,31MTT@2|Bacteria,1QJJZ@1224|Proteobacteria,1THKE@1236|Gammaproteobacteria,1XWII@135623|Vibrionales	135623|Vibrionales	S	Trans-membrane regulatory protein ToxS	toxS	GO:0005575,GO:0005623,GO:0005886,GO:0007154,GO:0007165,GO:0008150,GO:0009987,GO:0016020,GO:0023052,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0071944	-	ko:K10922	ko05111,map05111	-	-	-	ko00000,ko00001	-	-	-	ToxS
k141_2995_1	1123371.ATXH01000023_gene941	1.64e-33	128.0	COG1567@1|root,COG1567@2|Bacteria,2GIQ6@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	L	CRISPR-associated RAMP protein, Csm4 family	-	-	-	ko:K19139	-	-	-	-	ko00000,ko02048	-	-	-	-
k141_2995_2	879212.DespoDRAFT_02558	1.28e-47	168.0	COG1332@1|root,COG1332@2|Bacteria,1REN1@1224|Proteobacteria,42S5T@68525|delta/epsilon subdivisions,2WNQH@28221|Deltaproteobacteria,2MP4G@213118|Desulfobacterales	28221|Deltaproteobacteria	L	RAMP superfamily	-	-	-	ko:K19140	-	-	-	-	ko00000,ko02048	-	-	-	RAMPs
k141_2700_2	1499967.BAYZ01000093_gene4035	1.59e-55	188.0	28RXC@1|root,2ZE9F@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_2996_1	1499967.BAYZ01000177_gene5743	2.35e-06	50.1	COG2204@1|root,COG2204@2|Bacteria,2NQHI@2323|unclassified Bacteria	2|Bacteria	T	Sigma-54 interaction domain	-	-	-	ko:K07713	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
k141_2996_2	1121403.AUCV01000063_gene4181	4.95e-48	169.0	COG1361@1|root,COG1361@2|Bacteria,1R5HW@1224|Proteobacteria,42PWN@68525|delta/epsilon subdivisions,2WKV3@28221|Deltaproteobacteria,2MQ29@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Protein of unknown function (DUF1566)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1566
k141_1007_1	883081.HMPREF9698_00237	1.22e-20	92.4	COG0223@1|root,COG0223@2|Bacteria,1TQ32@1239|Firmicutes,4HART@91061|Bacilli,27FJN@186828|Carnobacteriaceae	91061|Bacilli	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	iSB619.SA_RS06010	Formyl_trans_C,Formyl_trans_N
k141_2998_1	1268240.ATFI01000004_gene4086	1.12e-39	137.0	COG3177@1|root,COG3177@2|Bacteria,4NR8T@976|Bacteroidetes,2FRZC@200643|Bacteroidia,4ASX3@815|Bacteroidaceae	976|Bacteroidetes	S	Domain of unknown function (DUF4157)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4157
k141_2999_1	96561.Dole_1886	2.06e-179	514.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,1MUJM@1224|Proteobacteria,42M2M@68525|delta/epsilon subdivisions,2WJ5H@28221|Deltaproteobacteria,2MHSU@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	guaB	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH,NMO
k141_1008_1	177437.HRM2_18920	5.72e-60	193.0	COG0755@1|root,COG0755@2|Bacteria,1RG6M@1224|Proteobacteria,43BH8@68525|delta/epsilon subdivisions,2X6VM@28221|Deltaproteobacteria,2MPIN@213118|Desulfobacterales	28221|Deltaproteobacteria	O	TIGRFAM cytochrome c-type biogenesis protein CcsB	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm
k141_1008_2	96561.Dole_2551	1.32e-171	493.0	COG0766@1|root,COG0766@2|Bacteria,1MUH7@1224|Proteobacteria,42MJT@68525|delta/epsilon subdivisions,2WJ7W@28221|Deltaproteobacteria,2MHNI@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
k141_2701_1	1304885.AUEY01000002_gene377	7.37e-95	293.0	COG4972@1|root,COG4972@2|Bacteria,1MX8P@1224|Proteobacteria,42M36@68525|delta/epsilon subdivisions,2WJFJ@28221|Deltaproteobacteria,2MID0@213118|Desulfobacterales	28221|Deltaproteobacteria	NU	TIGRFAM type IV pilus assembly protein PilM	pilM	-	-	ko:K02662	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilM_2
k141_2701_2	1265505.ATUG01000002_gene2046	8.15e-14	73.2	COG3166@1|root,COG3166@2|Bacteria,1Q1I0@1224|Proteobacteria,42W65@68525|delta/epsilon subdivisions,2WS79@28221|Deltaproteobacteria,2MK8I@213118|Desulfobacterales	28221|Deltaproteobacteria	NU	PFAM Fimbrial assembly	pilN	-	-	ko:K02663	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilN
k141_2701_3	1123392.AQWL01000002_gene1956	1.06e-15	79.7	COG3167@1|root,COG3167@2|Bacteria,1RBGW@1224|Proteobacteria,2VH68@28216|Betaproteobacteria,1KSS5@119069|Hydrogenophilales	119069|Hydrogenophilales	NU	Pilus assembly protein, PilO	-	-	-	ko:K02664	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilO
k141_3000_2	55601.VANGNB10_cI2142c	7.54e-70	215.0	COG0684@1|root,COG0684@2|Bacteria,1RH18@1224|Proteobacteria,1RS9U@1236|Gammaproteobacteria,1XX44@135623|Vibrionales	135623|Vibrionales	H	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions	-	-	-	ko:K02553	-	-	-	-	ko00000,ko03019	-	-	-	RraA-like
k141_2702_2	1238450.VIBNISOn1_1670022	4.34e-172	490.0	COG3867@1|root,COG3867@2|Bacteria,1R33X@1224|Proteobacteria,1RYK6@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	Arabinogalactan endo-beta-1,4-galactanase	ganB	-	3.2.1.89	ko:K01224	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_hydro_53
k141_2703_1	1034347.CAHJ01000009_gene1914	2.49e-25	110.0	arCOG04584@1|root,2ZYP7@2|Bacteria,1TQAQ@1239|Firmicutes,4HQFQ@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_1011_2	768066.HELO_3818	2.44e-154	445.0	COG0180@1|root,COG0180@2|Bacteria,1MV4T@1224|Proteobacteria,1RNDC@1236|Gammaproteobacteria,1XHCZ@135619|Oceanospirillales	135619|Oceanospirillales	J	Tryptophanyl-tRNA synthetase	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
k141_3307_2	1127673.GLIP_0332	1.46e-116	358.0	COG2199@1|root,COG3447@1|root,COG3447@2|Bacteria,COG3706@2|Bacteria,1R7GZ@1224|Proteobacteria,1RZEZ@1236|Gammaproteobacteria,4656I@72275|Alteromonadaceae	1236|Gammaproteobacteria	T	COG2199 FOG GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,MASE1
k141_3307_4	298386.PBPRA0461	0.0	934.0	COG1472@1|root,COG1472@2|Bacteria,1MVIV@1224|Proteobacteria,1RMA0@1236|Gammaproteobacteria,1XWNN@135623|Vibrionales	135623|Vibrionales	G	Fibronectin type III-like domain	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
k141_3310_1	177437.HRM2_32980	4.77e-20	85.9	COG0778@1|root,COG0778@2|Bacteria,1PG8V@1224|Proteobacteria,42SNE@68525|delta/epsilon subdivisions,2WQG4@28221|Deltaproteobacteria,2MPFJ@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
k141_1013_1	1328313.DS2_07658	7.45e-35	134.0	COG0790@1|root,COG1672@1|root,COG0790@2|Bacteria,COG1672@2|Bacteria,1R5T1@1224|Proteobacteria,1S1D6@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	PFAM Archaeal ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,TPR_8
k141_3002_1	1379281.AVAG01000092_gene594	4.81e-77	237.0	COG0834@1|root,COG0834@2|Bacteria,1R4IH@1224|Proteobacteria,43ATK@68525|delta/epsilon subdivisions,2X67W@28221|Deltaproteobacteria,2MGYC@213115|Desulfovibrionales	28221|Deltaproteobacteria	ET	Ligated ion channel L-glutamate- and glycine-binding site	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
k141_3311_1	1121396.KB892913_gene149	2.25e-25	113.0	COG2202@1|root,COG4191@1|root,COG2202@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42RC2@68525|delta/epsilon subdivisions,2X8JD@28221|Deltaproteobacteria,2MJQ0@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	-	-	-	-	-	-	-	-	-	-	-	-	PAS_9
k141_1014_1	933262.AXAM01000018_gene999	6.25e-192	548.0	COG0215@1|root,COG0215@2|Bacteria,1MV8H@1224|Proteobacteria,42M04@68525|delta/epsilon subdivisions,2WJJD@28221|Deltaproteobacteria,2MIN7@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e,tRNA-synt_1g
k141_1014_2	177437.HRM2_23320	3.5e-165	482.0	COG0556@1|root,COG0556@2|Bacteria,1MUFK@1224|Proteobacteria,42MFA@68525|delta/epsilon subdivisions,2WJ20@28221|Deltaproteobacteria,2MI3V@213118|Desulfobacterales	28221|Deltaproteobacteria	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
k141_3003_1	1120950.KB892739_gene4001	1.69e-79	270.0	COG1022@1|root,COG1022@2|Bacteria,2GIXQ@201174|Actinobacteria,4DNTY@85009|Propionibacteriales	201174|Actinobacteria	I	AMP-binding enzyme	fadD11_1	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
k141_2704_1	1304885.AUEY01000100_gene2607	0.0	1155.0	COG1148@1|root,COG1148@2|Bacteria,1QUM4@1224|Proteobacteria,42MPP@68525|delta/epsilon subdivisions,2WJ3U@28221|Deltaproteobacteria,2MIJ3@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM Pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Pyr_redox_2
k141_2704_2	1304885.AUEY01000100_gene2608	6.05e-236	657.0	COG0247@1|root,COG0247@2|Bacteria,1N5Q2@1224|Proteobacteria,42P5D@68525|delta/epsilon subdivisions,2WJ9I@28221|Deltaproteobacteria,2MI9D@213118|Desulfobacterales	28221|Deltaproteobacteria	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_17,Fer4_8
k141_2704_3	330214.NIDE2722	8.38e-152	458.0	COG0653@1|root,COG0653@2|Bacteria,3J0E5@40117|Nitrospirae	2|Bacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	-	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	SecA_DEAD,SecA_PP_bind,SecA_SW
k141_1675_1	223926.28809792	0.0	975.0	COG1299@1|root,COG1445@1|root,COG1762@1|root,COG1299@2|Bacteria,COG1445@2|Bacteria,COG1762@2|Bacteria,1R6GD@1224|Proteobacteria,1RZR0@1236|Gammaproteobacteria,1Y2P2@135623|Vibrionales	135623|Vibrionales	G	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2	-	-	2.7.1.202	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	M00273	R03232	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.2.1	-	-	PTS_EIIA_2,PTS_EIIC,PTS_IIB
k141_1675_2	945543.VIBR0546_19207	2.23e-191	542.0	COG1482@1|root,COG1482@2|Bacteria,1MUD8@1224|Proteobacteria,1RQX8@1236|Gammaproteobacteria,1XSH0@135623|Vibrionales	135623|Vibrionales	G	Belongs to the mannose-6-phosphate isomerase type 1 family	manA	-	5.3.1.8	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01819	RC00376	ko00000,ko00001,ko00002,ko01000	-	-	-	PMI_typeI
k141_1675_4	111781.Lepto7376_0557	5.73e-35	137.0	COG4564@1|root,COG4564@2|Bacteria	2|Bacteria	T	Single Cache domain 2	mcpV	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal,dCache_2,sCache_2
k141_1675_5	312309.VF_A0030	2.25e-142	409.0	COG0697@1|root,COG0697@2|Bacteria,1MZXM@1224|Proteobacteria,1RRID@1236|Gammaproteobacteria,1XTUE@135623|Vibrionales	135623|Vibrionales	EG	of the drug metabolite transporter (DMT) superfamily	-	-	-	-	-	-	-	-	-	-	-	-	EamA
k141_1675_6	223926.28808214	1.23e-125	364.0	COG1414@1|root,COG1414@2|Bacteria,1MUNW@1224|Proteobacteria,1RR06@1236|Gammaproteobacteria,1XU1E@135623|Vibrionales	135623|Vibrionales	K	helix_turn_helix isocitrate lyase regulation	kdgR	-	-	ko:K19333,ko:K21602	-	-	-	-	ko00000,ko03000	-	-	-	HTH_IclR,IclR
k141_1675_7	1348635.BBJY01000005_gene3339	6.67e-155	442.0	COG0524@1|root,COG0524@2|Bacteria,1MVG2@1224|Proteobacteria,1RNH5@1236|Gammaproteobacteria,1XSPP@135623|Vibrionales	135623|Vibrionales	G	COG0524 Sugar kinases, ribokinase family	-	-	2.7.1.45	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00061,M00308,M00631	R01541	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PfkB
k141_1675_8	1116375.VEJY3_16061	3.86e-120	346.0	COG0800@1|root,COG0800@2|Bacteria,1MUVJ@1224|Proteobacteria,1RPDF@1236|Gammaproteobacteria,1XU29@135623|Vibrionales	135623|Vibrionales	G	COG0800 2-keto-3-deoxy-6-phosphogluconate aldolase	-	-	4.1.2.14,4.1.3.42	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	M00008,M00061,M00308,M00631	R00470,R05605	RC00307,RC00308,RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldolase
k141_1675_9	247633.GP2143_06030	2.65e-23	93.6	COG3171@1|root,COG3171@2|Bacteria,1N8GZ@1224|Proteobacteria,1S9FQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein with unknown function (DUF469)	-	-	-	ko:K09923	-	-	-	-	ko00000	-	-	-	DUF469
k141_3157_20	674977.VMC_30710	7.29e-230	647.0	COG0144@1|root,COG3270@1|root,COG0144@2|Bacteria,COG3270@2|Bacteria,1NAY1@1224|Proteobacteria,1RP74@1236|Gammaproteobacteria,1XSE4@135623|Vibrionales	135623|Vibrionales	J	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA	rsmF	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.178	ko:K11392	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F,Methyltr_RsmF_N,Methyltranf_PUA
k141_3157_21	1517681.HW45_25090	2.49e-151	431.0	COG2996@1|root,COG2996@2|Bacteria,1MXC3@1224|Proteobacteria,1RS4D@1236|Gammaproteobacteria,1XTG1@135623|Vibrionales	135623|Vibrionales	S	protein conserved in bacteria	-	-	-	ko:K00243	-	-	-	-	ko00000	-	-	-	S1_2
k141_3157_22	55601.VANGNB10_cI1248c	6.67e-223	626.0	2CG2X@1|root,2Z7NT@2|Bacteria,1MW33@1224|Proteobacteria,1RQZI@1236|Gammaproteobacteria,1XSII@135623|Vibrionales	135623|Vibrionales	-	-	VP1614	-	-	-	-	-	-	-	-	-	-	-	-
k141_3157_23	1188252.AJYK01000104_gene13	8.43e-262	733.0	COG0737@1|root,COG0737@2|Bacteria,1MX03@1224|Proteobacteria,1RPX3@1236|Gammaproteobacteria,1XUQ9@135623|Vibrionales	135623|Vibrionales	F	Belongs to the 5'-nucleotidase family	ushA	GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008252,GO:0008253,GO:0009225,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0034641,GO:0042578,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0055086,GO:0071704,GO:1901135,GO:1901360	3.1.3.5,3.6.1.45	ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	5_nucleotid_C,Metallophos
k141_3157_24	55601.VANGNB10_cI1246	4.23e-97	295.0	COG1080@1|root,COG1080@2|Bacteria,1QUXJ@1224|Proteobacteria,1T250@1236|Gammaproteobacteria,1XU1A@135623|Vibrionales	135623|Vibrionales	G	PEP-utilising enzyme, TIM barrel domain	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers_C
k141_3157_25	672.VV93_v1c15110	1.38e-72	222.0	COG1666@1|root,COG1666@2|Bacteria,1RDTF@1224|Proteobacteria,1S3RU@1236|Gammaproteobacteria,1XX34@135623|Vibrionales	135623|Vibrionales	S	Belongs to the UPF0234 family	yajQ	-	-	ko:K09767	-	-	-	-	ko00000	-	-	-	DUF520
k141_3157_26	1191299.AJYX01000086_gene3108	2.1e-103	312.0	COG1648@1|root,COG1648@2|Bacteria,1RB3H@1224|Proteobacteria,1SPHW@1236|Gammaproteobacteria,1XT8S@135623|Vibrionales	135623|Vibrionales	H	COG1648 Siroheme synthase (precorrin-2 oxidase ferrochelatase domain)	cysG	-	1.3.1.76,4.99.1.4	ko:K02304	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03947	RC01012,RC01034	ko00000,ko00001,ko00002,ko01000	-	-	-	CysG_dimeriser,NAD_binding_7,Sirohm_synth_M
k141_3157_27	1280001.BAOA01000077_gene3082	1.53e-181	512.0	COG0834@1|root,COG0834@2|Bacteria,1MV5D@1224|Proteobacteria,1RNJJ@1236|Gammaproteobacteria,1XSSI@135623|Vibrionales	135623|Vibrionales	ET	COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain	aapJ	-	-	ko:K09969	ko02010,map02010	M00232	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3.18,3.A.1.3.7,3.A.1.3.8	-	-	SBP_bac_3
k141_3157_28	1348635.BBJY01000005_gene3293	6.84e-116	336.0	COG0670@1|root,COG0670@2|Bacteria,1MU69@1224|Proteobacteria,1RRVZ@1236|Gammaproteobacteria,1XTWT@135623|Vibrionales	135623|Vibrionales	S	Belongs to the BI1 family	yccA	-	-	ko:K19416	-	M00742	-	-	ko00000,ko00002,ko02000	1.A.14.2.1	-	-	Bax1-I
k141_3157_29	945550.VISI1226_13953	1.39e-59	185.0	COG2920@1|root,COG2920@2|Bacteria,1RGVG@1224|Proteobacteria,1S5ZA@1236|Gammaproteobacteria,1XXBF@135623|Vibrionales	135623|Vibrionales	P	part of a sulfur-relay system	tusE	-	-	ko:K11179	ko04122,map04122	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	DsrC
k141_3157_30	1348635.BBJY01000005_gene3295	6.7e-34	119.0	COG1254@1|root,COG1254@2|Bacteria,1N6NU@1224|Proteobacteria,1SCPF@1236|Gammaproteobacteria,1XYDK@135623|Vibrionales	135623|Vibrionales	C	COG1254 Acylphosphatases	acyP	GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818	3.6.1.7	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	-	R00317,R01421,R01515	RC00043	ko00000,ko00001,ko01000	-	-	-	Acylphosphatase
k141_3157_31	29495.EA26_07655	2.5e-236	655.0	COG1092@1|root,COG1092@2|Bacteria,1MUGB@1224|Proteobacteria,1RN7Z@1236|Gammaproteobacteria,1XTVB@135623|Vibrionales	135623|Vibrionales	J	Specifically methylates the cytosine at position 1962 (m5C1962) of 23S rRNA	rlmI	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
k141_3157_32	1114922.CIFAM_27_00340	4.87e-24	96.3	2D7FD@1|root,32TNY@2|Bacteria,1NAHU@1224|Proteobacteria,1S9DD@1236|Gammaproteobacteria,3WYFJ@544|Citrobacter	1236|Gammaproteobacteria	S	Domain of unknown function (DUF1992)	yhdN	-	-	-	-	-	-	-	-	-	-	-	DUF1992
k141_3157_33	1116375.VEJY3_17176	6.32e-112	333.0	COG1767@1|root,COG1767@2|Bacteria,1N9IK@1224|Proteobacteria,1RYW6@1236|Gammaproteobacteria,1XWIV@135623|Vibrionales	135623|Vibrionales	F	triphosphoribosyl-dephospho-CoA synthase activity	citG	GO:0003674,GO:0003824,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016780,GO:0019538,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0046917,GO:0051186,GO:0051188,GO:0051189,GO:0051191,GO:0071704,GO:1901564,GO:1901576	2.4.2.52	ko:K05966	ko02020,map02020	-	R09675	RC00049,RC00063	ko00000,ko00001,ko01000	-	-	-	CitG
k141_3158_1	1120999.JONM01000010_gene4111	8.38e-26	109.0	COG2200@1|root,COG2200@2|Bacteria,1PDZY@1224|Proteobacteria,2VM72@28216|Betaproteobacteria,2KPD2@206351|Neisseriales	206351|Neisseriales	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL
k141_2131_1	997350.HMPREF9129_0436	1.31e-13	71.2	COG1433@1|root,COG1433@2|Bacteria,1V7KS@1239|Firmicutes,24MUB@186801|Clostridia,22HWR@1570339|Peptoniphilaceae	186801|Clostridia	S	Putative redox-active protein (C_GCAxxG_C_C)	-	-	-	-	-	-	-	-	-	-	-	-	C_GCAxxG_C_C
k141_4554_1	497321.C664_10822	6.14e-16	78.2	COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,2VMKP@28216|Betaproteobacteria,2KV5U@206389|Rhodocyclales	206389|Rhodocyclales	H	Acetolactate synthase	ilvB	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
k141_4554_2	36080.S2JSW8	0.000451	45.1	COG0440@1|root,KOG2663@2759|Eukaryota,38EH4@33154|Opisthokonta,3NUVU@4751|Fungi,1GT4G@112252|Fungi incertae sedis	4751|Fungi	E	Mortierella verticillata NRRL 6337 acetolactate synthase I III small subunit (309 aa)	ILV6	GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005948,GO:0006082,GO:0006520,GO:0006549,GO:0006551,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009098,GO:0009099,GO:0009295,GO:0009987,GO:0016053,GO:0019752,GO:0030234,GO:0031974,GO:0032991,GO:0042645,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0050790,GO:0065007,GO:0065009,GO:0070013,GO:0071704,GO:0098772,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234,GO:1990610	2.2.1.6	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,ALS_ss_C
k141_1812_1	1348635.BBJY01000007_gene166	1.13e-215	605.0	2AG8V@1|root,316E7@2|Bacteria,1PXEQ@1224|Proteobacteria,1TIV5@1236|Gammaproteobacteria,1XZQY@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_1812_2	1348635.BBJY01000007_gene165	1.22e-307	841.0	29YUS@1|root,30KR6@2|Bacteria,1PXGV@1224|Proteobacteria,1TJ67@1236|Gammaproteobacteria,1Y0NZ@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_1812_3	1348635.BBJY01000007_gene164	1.5e-203	570.0	2DBD6@1|root,2Z8I5@2|Bacteria,1PYR3@1224|Proteobacteria,1TJ1Q@1236|Gammaproteobacteria,1Y0AY@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_1812_5	1316932.MHH_c18850	5.88e-32	116.0	2906P@1|root,2ZMWG@2|Bacteria,1P8CS@1224|Proteobacteria,1STDQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_1812_9	1219072.VHA01S_049_00230	1.67e-32	117.0	2E834@1|root,332H4@2|Bacteria,1N8W8@1224|Proteobacteria,1SDS3@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Domain of unknown function (DUF4258)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4258
k141_1812_10	1202962.KB907150_gene1503	8.94e-66	204.0	COG2944@1|root,COG2944@2|Bacteria,1N75U@1224|Proteobacteria,1SCEY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	transcriptional regulator	-	-	-	ko:K07726	-	-	-	-	ko00000,ko03000	-	-	-	HTH_3
k141_4888_1	1232437.KL662006_gene4434	3.99e-75	241.0	COG0784@1|root,COG4191@1|root,COG0784@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MC4@68525|delta/epsilon subdivisions,2WIZU@28221|Deltaproteobacteria,2MHWA@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	ABC_sub_bind,GAF_2,HATPase_c,HisKA,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
k141_4888_3	1121403.AUCV01000002_gene653	7.6e-50	171.0	COG3022@1|root,COG3022@2|Bacteria,1MUAF@1224|Proteobacteria,42RH2@68525|delta/epsilon subdivisions,2WNS0@28221|Deltaproteobacteria,2MKGN@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Peroxide stress protein YaaA	-	-	-	ko:K09861	-	-	-	-	ko00000	-	-	-	H2O2_YaaD
k141_4888_4	656519.Halsa_0235	1.71e-17	87.0	COG2801@1|root,COG2801@2|Bacteria,1TQSP@1239|Firmicutes,249I9@186801|Clostridia,3WB4A@53433|Halanaerobiales	186801|Clostridia	L	PFAM Integrase catalytic region	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,HTH_Tnp_1,rve,rve_3
k141_1139_3	1304885.AUEY01000020_gene3490	6.97e-107	326.0	COG0745@1|root,COG0745@2|Bacteria,1NE8H@1224|Proteobacteria,42NEH@68525|delta/epsilon subdivisions,2WK1M@28221|Deltaproteobacteria,2MHU4@213118|Desulfobacterales	28221|Deltaproteobacteria	T	PFAM response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Cytidylate_kin2,Response_reg
k141_4555_1	243277.VC_1758	1.61e-11	63.2	COG0582@1|root,COG0582@2|Bacteria,1MU23@1224|Proteobacteria,1RMJ1@1236|Gammaproteobacteria,1XTXF@135623|Vibrionales	135623|Vibrionales	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Arm-DNA-bind_3,Phage_int_SAM_3,Phage_integrase
k141_759_1	754476.Q7A_2108	1e-91	273.0	COG3541@1|root,COG3541@2|Bacteria,1MYFT@1224|Proteobacteria,1RY9F@1236|Gammaproteobacteria,4623E@72273|Thiotrichales	72273|Thiotrichales	S	Predicted nucleotidyltransferase	-	-	-	ko:K07074	-	-	-	-	ko00000	-	-	-	Nuc-transf
k141_511_1	1219080.VEZ01S_01_01690	1.31e-252	695.0	COG1062@1|root,COG1062@2|Bacteria,1MUK4@1224|Proteobacteria,1RNQ4@1236|Gammaproteobacteria,1XSME@135623|Vibrionales	135623|Vibrionales	C	Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily	frmA	-	1.1.1.1,1.1.1.284	ko:K00121	ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R06983,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01715,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
k141_511_2	55601.VANGNB10_cI0745c	1.7e-145	416.0	COG0627@1|root,COG0627@2|Bacteria,1MUID@1224|Proteobacteria,1RMR3@1236|Gammaproteobacteria,1XUG1@135623|Vibrionales	135623|Vibrionales	S	Serine hydrolase involved in the detoxification of formaldehyde	yeiG	-	3.1.2.12	ko:K01070	ko00680,ko01120,ko01200,map00680,map01120,map01200	-	R00527	RC00167,RC00320	ko00000,ko00001,ko01000	-	CE1	-	Esterase
k141_3159_1	796620.VIBC2010_07269	4.18e-65	228.0	COG4618@1|root,COG4618@2|Bacteria,1NTI5@1224|Proteobacteria,1T1HR@1236|Gammaproteobacteria,1XUAM@135623|Vibrionales	135623|Vibrionales	V	COG4618 ABC-type protease lipase transport system, ATPase and permease components	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
k141_2132_2	335543.Sfum_3950	1.7e-91	277.0	COG0834@1|root,COG0834@2|Bacteria,1MV3Q@1224|Proteobacteria,42MKG@68525|delta/epsilon subdivisions,2WPT1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	ET	Bacterial periplasmic substrate-binding proteins	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
k141_2132_3	931276.Cspa_c46340	1.37e-31	122.0	COG0765@1|root,COG0765@2|Bacteria,1UYQ8@1239|Firmicutes,24EAA@186801|Clostridia,36HD1@31979|Clostridiaceae	186801|Clostridia	E	acid ABC transporter	-	-	-	ko:K02029	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	BPD_transp_1
k141_2132_4	1537994.JQFW01000057_gene258	5.44e-46	167.0	COG2199@1|root,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,1RWQ8@1236|Gammaproteobacteria,4682A@72275|Alteromonadaceae	1236|Gammaproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
k141_4159_1	945543.VIBR0546_01406	0.0	928.0	COG2911@1|root,COG2911@2|Bacteria,1MUVD@1224|Proteobacteria,1RMMF@1236|Gammaproteobacteria,1XV86@135623|Vibrionales	135623|Vibrionales	S	protein conserved in bacteria	-	-	-	ko:K09800	-	-	-	-	ko00000,ko02000	-	-	-	TamB
k141_4159_2	675814.VIC_001000	1.02e-145	426.0	COG0729@1|root,COG0729@2|Bacteria,1MUKM@1224|Proteobacteria,1RNQ3@1236|Gammaproteobacteria,1XV1N@135623|Vibrionales	135623|Vibrionales	M	COG0729 Outer membrane protein	ytfM	-	-	ko:K07278	-	-	-	-	ko00000,ko02000	1.B.33.2.4	-	-	Bac_surface_Ag,POTRA,POTRA_TamA_1
k141_760_1	1304885.AUEY01000004_gene966	1.31e-158	465.0	COG1960@1|root,COG1960@2|Bacteria,1MU20@1224|Proteobacteria,42MUH@68525|delta/epsilon subdivisions,2WJ16@28221|Deltaproteobacteria,2MHYV@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Acyl-CoA dehydrogenase N terminal	-	-	-	ko:K09456	-	-	-	-	ko00000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_C,Acyl-CoA_dh_M,Acyl-CoA_dh_N,AcylCoA_DH_N
k141_1815_1	1121403.AUCV01000004_gene2005	2.61e-22	96.7	COG0404@1|root,COG0404@2|Bacteria,1MV96@1224|Proteobacteria,42QM6@68525|delta/epsilon subdivisions,2WJ8G@28221|Deltaproteobacteria,2MI19@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Belongs to the GcvT family	gcvT	-	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
k141_1815_2	34506.g3277	3.44e-35	135.0	COG0404@1|root,COG0509@1|root,COG1003@1|root,KOG2040@2759|Eukaryota,KOG2770@2759|Eukaryota,KOG3373@2759|Eukaryota,38E0D@33154|Opisthokonta,3BYTR@33208|Metazoa,3DE2V@33213|Bilateria,40R16@6231|Nematoda,1M81D@119089|Chromadorea,4173J@6236|Rhabditida	33154|Opisthokonta	E	Glycine cleavage H-protein	-	-	-	-	-	-	-	-	-	-	-	-	GCV_H,GCV_T,GDC-P
k141_1815_3	1121405.dsmv_2528	1.61e-166	481.0	COG0403@1|root,COG0403@2|Bacteria,1MVC1@1224|Proteobacteria,42MQ1@68525|delta/epsilon subdivisions,2WJII@28221|Deltaproteobacteria,2MHPJ@213118|Desulfobacterales	28221|Deltaproteobacteria	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvPA	-	1.4.4.2	ko:K00282	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	-	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko01000	-	-	-	GDC-P
k141_4556_2	745310.G432_03060	2.81e-08	60.1	COG1566@1|root,COG1566@2|Bacteria,1MU7I@1224|Proteobacteria,2TS39@28211|Alphaproteobacteria,2K1WC@204457|Sphingomonadales	204457|Sphingomonadales	V	Secretion protein, HlyD	-	-	-	ko:K03543	-	M00701	-	-	ko00000,ko00002,ko02000	8.A.1.1	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
k141_4556_3	1207076.ALAT01000185_gene2641	6.43e-28	112.0	COG1566@1|root,COG1566@2|Bacteria,1MWG0@1224|Proteobacteria,1RRE3@1236|Gammaproteobacteria,1Z1A6@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	V	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	fusE	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
k141_4160_1	398767.Glov_3025	1.95e-43	148.0	COG3153@1|root,COG3153@2|Bacteria,1RE2M@1224|Proteobacteria,42RUI@68525|delta/epsilon subdivisions,2WNFQ@28221|Deltaproteobacteria,43T6Z@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Acetyltransferase (GNAT) domain	-	-	-	ko:K03824	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_7
k141_1142_1	1304885.AUEY01000003_gene518	3.11e-84	251.0	COG1406@1|root,COG1406@2|Bacteria,1RATZ@1224|Proteobacteria,42R2Q@68525|delta/epsilon subdivisions,2WP6F@28221|Deltaproteobacteria,2MJQ2@213118|Desulfobacterales	28221|Deltaproteobacteria	N	Chemotaxis phosphatase CheX	-	-	-	ko:K03409	ko02030,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheX
k141_1142_2	1304885.AUEY01000003_gene517	5.5e-17	77.8	2DP65@1|root,330PS@2|Bacteria,1NCIJ@1224|Proteobacteria,42W40@68525|delta/epsilon subdivisions,2WS36@28221|Deltaproteobacteria,2MM5V@213118|Desulfobacterales	28221|Deltaproteobacteria	S	PilZ domain	-	-	-	-	-	-	-	-	-	-	-	-	PilZ
k141_1142_3	1304885.AUEY01000003_gene515	3.37e-196	563.0	COG2204@1|root,COG2206@1|root,COG2204@2|Bacteria,COG2206@2|Bacteria,1RAQS@1224|Proteobacteria,42MEJ@68525|delta/epsilon subdivisions,2X71A@28221|Deltaproteobacteria,2MHS0@213118|Desulfobacterales	28221|Deltaproteobacteria	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GAF_3,GGDEF,HD,Response_reg
k141_1142_4	1121405.dsmv_0958	1.88e-91	286.0	COG1061@1|root,COG1061@2|Bacteria,1QWMJ@1224|Proteobacteria,42NXF@68525|delta/epsilon subdivisions,2WJWA@28221|Deltaproteobacteria,2MHPY@213118|Desulfobacterales	28221|Deltaproteobacteria	L	type III restriction protein res subunit	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,ResIII
k141_512_1	1348635.BBJY01000005_gene3350	5.71e-140	424.0	COG3279@1|root,COG5001@1|root,COG3279@2|Bacteria,COG5001@2|Bacteria,1MUNI@1224|Proteobacteria,1RRUX@1236|Gammaproteobacteria,1XSJK@135623|Vibrionales	135623|Vibrionales	T	Domain of unknown function (DUF3369)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3369,EAL,GGDEF,Response_reg
k141_512_3	1122207.MUS1_14825	8.15e-76	256.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1S1S6@1236|Gammaproteobacteria,1XR4U@135619|Oceanospirillales	135619|Oceanospirillales	NT	Nitrate and nitrite sensing	-	-	-	-	-	-	-	-	-	-	-	-	MCPsignal,NIT
k141_5151_2	1511.CLOST_1676	9.32e-66	210.0	COG3409@1|root,COG3409@2|Bacteria,1VGC4@1239|Firmicutes,24R4H@186801|Clostridia	186801|Clostridia	M	Flagellar rod assembly protein muramidase FlgJ	-	-	-	-	-	-	-	-	-	-	-	-	CW_binding_1,PG_binding_1
k141_5151_3	1216932.CM240_3157	2.78e-57	184.0	COG0262@1|root,COG0262@2|Bacteria,1VAUA@1239|Firmicutes,24G7Y@186801|Clostridia,36IEA@31979|Clostridiaceae	186801|Clostridia	H	Riboflavin biosynthesis protein RibD	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
k141_5151_4	526222.Desal_1269	0.0	1055.0	COG0376@1|root,COG0376@2|Bacteria,1MUBF@1224|Proteobacteria,42MZ4@68525|delta/epsilon subdivisions,2WJPB@28221|Deltaproteobacteria,2MABY@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity	katG	GO:0000302,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016684,GO:0016999,GO:0017001,GO:0017144,GO:0020037,GO:0033554,GO:0034599,GO:0034614,GO:0035690,GO:0042221,GO:0042493,GO:0042542,GO:0042737,GO:0042743,GO:0042744,GO:0044237,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0046906,GO:0048037,GO:0050896,GO:0051186,GO:0051187,GO:0051716,GO:0055114,GO:0070301,GO:0070887,GO:0071236,GO:0072593,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901363,GO:1901700,GO:1901701,GO:1990748	1.11.1.21	ko:K03782	ko00360,ko00380,ko00940,ko00983,ko01100,ko01110,map00360,map00380,map00940,map00983,map01100,map01110	-	R00602,R00698,R02596,R02670,R03919,R04007,R07443,R11906	RC00034,RC00213,RC00767,RC02141	ko00000,ko00001,ko01000	-	-	-	peroxidase
k141_5151_5	1033737.CAEV01000002_gene2214	8.54e-75	229.0	COG2320@1|root,COG2320@2|Bacteria,1V3IB@1239|Firmicutes,24IQJ@186801|Clostridia,36FVN@31979|Clostridiaceae	186801|Clostridia	K	GrpB protein	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,GrpB,NUDIX
k141_5151_7	411470.RUMGNA_03685	1.11e-169	489.0	COG0402@1|root,COG0402@2|Bacteria,1TP43@1239|Firmicutes,248IX@186801|Clostridia,3XZ7R@572511|Blautia	186801|Clostridia	F	COG COG0402 Cytosine deaminase and related metal-dependent hydrolases	guaD	-	3.5.4.3	ko:K01487	ko00230,ko01100,map00230,map01100	-	R01676	RC00204	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
k141_1471_1	1408422.JHYF01000009_gene2155	1e-43	148.0	COG1788@1|root,COG1788@2|Bacteria,1V21Q@1239|Firmicutes,25E61@186801|Clostridia,36UK0@31979|Clostridiaceae	186801|Clostridia	I	TIGRFAM 3-oxoacid CoA-transferase, A subunit	-	-	2.8.3.8,2.8.3.9	ko:K01034	ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020	-	R01179,R01359,R01365,R07832	RC00012,RC00014	ko00000,ko00001,ko01000	-	-	-	CoA_trans
k141_1471_2	857293.CAAU_1571	1.27e-99	295.0	COG2057@1|root,COG2057@2|Bacteria,1TNY5@1239|Firmicutes,247ZM@186801|Clostridia,36GAR@31979|Clostridiaceae	186801|Clostridia	I	3-oxoacid CoA-transferase, B subunit	ctfB	-	2.8.3.8,2.8.3.9	ko:K01035	ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020	-	R01179,R01359,R01365,R07832	RC00012,RC00014	ko00000,ko00001,ko01000	-	-	-	CoA_trans
k141_1471_3	177437.HRM2_43080	1.85e-226	634.0	COG2031@1|root,COG2031@2|Bacteria,1MV5A@1224|Proteobacteria,42PE0@68525|delta/epsilon subdivisions,2WITD@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	fatty acid transporter	atoE	-	-	ko:K02106	ko02020,map02020	-	-	-	ko00000,ko00001	2.A.73.1	-	-	SCFA_trans
k141_1841_1	177437.HRM2_04720	2.82e-184	544.0	COG3243@1|root,COG3243@2|Bacteria,1MUNE@1224|Proteobacteria,42PDZ@68525|delta/epsilon subdivisions,2WIW0@28221|Deltaproteobacteria,2MJ1X@213118|Desulfobacterales	28221|Deltaproteobacteria	I	Protein of unknown function (DUF3141)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3141,TerB
k141_1841_2	1121405.dsmv_0150	4.7e-87	268.0	COG0061@1|root,COG0061@2|Bacteria,1MUBC@1224|Proteobacteria,42MP8@68525|delta/epsilon subdivisions,2WKMR@28221|Deltaproteobacteria,2MIXA@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	nadK	-	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	NAD_kinase
k141_3174_1	243277.VC_A0896	3.75e-11	62.0	COG0364@1|root,COG0364@2|Bacteria,1MUN0@1224|Proteobacteria,1RN76@1236|Gammaproteobacteria,1XSC7@135623|Vibrionales	135623|Vibrionales	G	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone	zwf	-	1.1.1.363,1.1.1.49	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	M00004,M00006,M00008	R00835,R02736,R10907	RC00001,RC00066	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	G6PD_C,G6PD_N
k141_3174_2	672.VV93_v1c14820	3.19e-131	377.0	COG0363@1|root,COG0363@2|Bacteria,1QXIZ@1224|Proteobacteria,1RZTR@1236|Gammaproteobacteria,1Y271@135623|Vibrionales	135623|Vibrionales	G	Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase	pgl	-	3.1.1.31	ko:K01057	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	M00004,M00006,M00008	R02035	RC00537	ko00000,ko00001,ko00002,ko01000	-	-	-	Glucosamine_iso
k141_3174_3	1280001.BAOA01000018_gene321	4.08e-45	157.0	COG0362@1|root,COG0362@2|Bacteria,1MVV8@1224|Proteobacteria,1RM7P@1236|Gammaproteobacteria,1XTAI@135623|Vibrionales	135623|Vibrionales	H	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH	gnd	-	1.1.1.343,1.1.1.44	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	M00004,M00006	R01528,R10221	RC00001,RC00539	ko00000,ko00001,ko00002,ko01000	-	-	-	6PGD,NAD_binding_2
k141_1472_2	1265505.ATUG01000002_gene1590	2.6e-88	264.0	COG0655@1|root,COG0655@2|Bacteria,1RAZP@1224|Proteobacteria,42QXN@68525|delta/epsilon subdivisions,2WMR3@28221|Deltaproteobacteria,2MJJH@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Flavodoxin-like fold	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
k141_3175_1	754436.JCM19237_2389	6.81e-54	179.0	COG1116@1|root,COG1116@2|Bacteria,1RASI@1224|Proteobacteria,1RY7H@1236|Gammaproteobacteria,1XU0G@135623|Vibrionales	135623|Vibrionales	P	COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component	-	-	-	ko:K15600	ko02010,map02010	M00442	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.17.3,3.A.1.17.6	-	-	ABC_tran
k141_2788_1	94122.Shewana3_2750	7.04e-58	194.0	COG0845@1|root,COG0845@2|Bacteria,1R3U4@1224|Proteobacteria,1T2P1@1236|Gammaproteobacteria,2QEQ5@267890|Shewanellaceae	1236|Gammaproteobacteria	M	Biotin-lipoyl like	-	-	-	ko:K01993	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3
k141_2788_2	1236541.BALL01000001_gene203	7.77e-154	441.0	COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,1RMM4@1236|Gammaproteobacteria,2Q9BN@267890|Shewanellaceae	1236|Gammaproteobacteria	V	PFAM ABC transporter related	ybhF	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
k141_1245_39	500633.CLOHIR_01600	5.15e-39	131.0	COG0361@1|root,COG0361@2|Bacteria,1V9ZK@1239|Firmicutes,24MQE@186801|Clostridia,25RSC@186804|Peptostreptococcaceae	186801|Clostridia	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	-	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
k141_1245_40	1321778.HMPREF1982_00342	1.5e-19	83.6	COG2163@1|root,COG2163@2|Bacteria,1VEPA@1239|Firmicutes,24QMU@186801|Clostridia	186801|Clostridia	J	COG2163 Ribosomal protein L14E L6E L27E	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_1245_41	1286171.EAL2_c01790	1.02e-131	379.0	COG0024@1|root,COG0024@2|Bacteria,1TQC1@1239|Firmicutes,248I8@186801|Clostridia,25V68@186806|Eubacteriaceae	186801|Clostridia	E	Psort location Cytoplasmic, score	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
k141_1245_42	1121289.JHVL01000024_gene141	5.55e-104	306.0	COG0563@1|root,COG0563@2|Bacteria,1TP27@1239|Firmicutes,247YN@186801|Clostridia,36ETU@31979|Clostridiaceae	186801|Clostridia	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iHN637.CLJU_RS20110	ADK,ADK_lid
k141_1245_43	1511.CLOST_2178	1.47e-206	582.0	COG0201@1|root,COG0201@2|Bacteria,1TPHB@1239|Firmicutes,248T9@186801|Clostridia,25QD8@186804|Peptostreptococcaceae	186801|Clostridia	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	-	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
k141_1245_44	1511.CLOST_2179	3.35e-74	225.0	COG0200@1|root,COG0200@2|Bacteria,1V3KE@1239|Firmicutes,24HAJ@186801|Clostridia,25RKE@186804|Peptostreptococcaceae	186801|Clostridia	J	binds to the 23S rRNA	rplO	-	-	ko:K02876	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27A
k141_1245_45	1408422.JHYF01000014_gene287	1.42e-18	77.8	COG1841@1|root,COG1841@2|Bacteria	2|Bacteria	J	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	rpmD	GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02907	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L30
k141_1245_46	1476973.JMMB01000007_gene138	2.36e-93	275.0	COG0098@1|root,COG0098@2|Bacteria,1V1B1@1239|Firmicutes,24G5D@186801|Clostridia,25RBS@186804|Peptostreptococcaceae	186801|Clostridia	J	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body	rpsE	-	-	ko:K02988	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S5,Ribosomal_S5_C
k141_1245_47	997346.HMPREF9374_2862	2.2e-53	170.0	COG0256@1|root,COG0256@2|Bacteria,1V6DM@1239|Firmicutes,4HIGF@91061|Bacilli,27C1D@186824|Thermoactinomycetaceae	91061|Bacilli	J	Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast	rplR	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904	-	ko:K02881	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L18p
k141_1245_48	1121324.CLIT_24c00520	9.13e-103	300.0	COG0097@1|root,COG0097@2|Bacteria,1V1FC@1239|Firmicutes,2496R@186801|Clostridia	186801|Clostridia	J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center	rplF	-	-	ko:K02933	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L6
k141_1245_49	500633.CLOHIR_01591	1.13e-78	235.0	COG0096@1|root,COG0096@2|Bacteria,1V3KK@1239|Firmicutes,24HCP@186801|Clostridia,25RBC@186804|Peptostreptococcaceae	186801|Clostridia	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit	rpsH	-	-	ko:K02994	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S8
k141_1245_50	1121115.AXVN01000046_gene2971	4.67e-34	117.0	COG0199@1|root,COG0199@2|Bacteria,1VEF6@1239|Firmicutes,24QR1@186801|Clostridia,3Y0DU@572511|Blautia	186801|Clostridia	J	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site	rpsN	-	-	ko:K02954	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S14
k141_1245_51	864565.HMPREF0379_1899	4.23e-95	280.0	COG0094@1|root,COG0094@2|Bacteria,1TPE0@1239|Firmicutes,247X0@186801|Clostridia,25R4D@186804|Peptostreptococcaceae	186801|Clostridia	J	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits	rplE	-	-	ko:K02931	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L5,Ribosomal_L5_C
k141_1245_52	1291050.JAGE01000001_gene2103	4.4e-35	123.0	COG0198@1|root,COG0198@2|Bacteria,1V9ZQ@1239|Firmicutes,24MY0@186801|Clostridia,3WJBH@541000|Ruminococcaceae	186801|Clostridia	J	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit	rplX	-	-	ko:K02895	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KOW,ribosomal_L24
k141_1245_53	1408823.AXUS01000017_gene1125	2.54e-68	208.0	COG0093@1|root,COG0093@2|Bacteria,1V3N0@1239|Firmicutes,24H98@186801|Clostridia,25RF9@186804|Peptostreptococcaceae	186801|Clostridia	J	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome	rplN	-	-	ko:K02874	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L14
k141_1245_54	500633.CLOHIR_01586	8.81e-44	143.0	COG0186@1|root,COG0186@2|Bacteria,1V9YC@1239|Firmicutes,24MSW@186801|Clostridia,25RSK@186804|Peptostreptococcaceae	186801|Clostridia	J	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA	rpsQ	-	-	ko:K02961	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S17
k141_1245_55	596330.HMPREF0628_0300	1.15e-22	89.0	COG0255@1|root,COG0255@2|Bacteria,1VEME@1239|Firmicutes,24QV1@186801|Clostridia,22HW8@1570339|Peptoniphilaceae	186801|Clostridia	J	Belongs to the universal ribosomal protein uL29 family	rpmC	-	-	ko:K02904	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L29
k141_1245_56	350688.Clos_0499	8.34e-82	244.0	COG0197@1|root,COG0197@2|Bacteria,1V1AY@1239|Firmicutes,24FQX@186801|Clostridia,36E4K@31979|Clostridiaceae	186801|Clostridia	J	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs	rplP	-	-	ko:K02878	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L16
k141_1245_57	1511.CLOST_2192	3.03e-113	332.0	COG0092@1|root,COG0092@2|Bacteria,1TPCP@1239|Firmicutes,24833@186801|Clostridia,25QNG@186804|Peptostreptococcaceae	186801|Clostridia	J	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation	rpsC	-	-	ko:K02982	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KH_2,Ribosomal_S3_C
k141_1245_58	350688.Clos_0497	3.18e-45	149.0	COG0091@1|root,COG0091@2|Bacteria,1V6PU@1239|Firmicutes,24JF4@186801|Clostridia,36JMN@31979|Clostridiaceae	186801|Clostridia	J	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome	rplV	-	-	ko:K02890	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L22
k141_1245_59	1286171.EAL2_c01610	1.3e-52	166.0	COG0185@1|root,COG0185@2|Bacteria,1V6CX@1239|Firmicutes,24JN3@186801|Clostridia,25WMJ@186806|Eubacteriaceae	186801|Clostridia	J	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA	rpsS	-	-	ko:K02965	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S19
k141_1245_60	445973.CLOBAR_00097	1.65e-153	436.0	COG0090@1|root,COG0090@2|Bacteria,1TP9X@1239|Firmicutes,247XY@186801|Clostridia,25R5V@186804|Peptostreptococcaceae	186801|Clostridia	J	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity	rplB	-	-	ko:K02886	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L2,Ribosomal_L2_C
k141_1245_61	1408422.JHYF01000014_gene302	1.49e-41	138.0	COG0089@1|root,COG0089@2|Bacteria,1VA4W@1239|Firmicutes,24MN8@186801|Clostridia,36JH0@31979|Clostridiaceae	186801|Clostridia	J	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome	rplW	-	-	ko:K02892	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L23
k141_1245_62	350688.Clos_0493	2.34e-100	296.0	COG0088@1|root,COG0088@2|Bacteria,1TPGW@1239|Firmicutes,248SY@186801|Clostridia,36DFP@31979|Clostridiaceae	186801|Clostridia	J	Forms part of the polypeptide exit tunnel	rplD	-	-	ko:K02926	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L4
k141_1245_63	1286171.EAL2_c01570	8.85e-104	305.0	COG0087@1|root,COG0087@2|Bacteria,1TPFT@1239|Firmicutes,247NH@186801|Clostridia,25VIA@186806|Eubacteriaceae	186801|Clostridia	J	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit	rplC	-	-	ko:K02906	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L3
k141_4650_1	1123372.AUIT01000010_gene392	2.54e-05	45.4	COG2331@1|root,COG2331@2|Bacteria,2GI2F@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	S	Zinc ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
k141_4650_2	1121405.dsmv_2542	1.79e-218	620.0	COG0007@1|root,COG1587@1|root,COG0007@2|Bacteria,COG1587@2|Bacteria,1MUI0@1224|Proteobacteria,42MCB@68525|delta/epsilon subdivisions,2WIRJ@28221|Deltaproteobacteria,2MISA@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Belongs to the precorrin methyltransferase family	hemD	-	1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.4	ko:K02302,ko:K02303,ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03165,R03194,R03947	RC00003,RC00871,RC01012,RC01034,RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4,TP_methylase
k141_4650_3	1086011.HJ01_03564	6.04e-46	152.0	COG1051@1|root,COG1051@2|Bacteria	2|Bacteria	F	GDP-mannose mannosyl hydrolase activity	rppH_2	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
k141_4650_4	715451.ambt_20280	0.000124	42.4	COG0607@1|root,305JH@2|Bacteria,1QQTN@1224|Proteobacteria,1RTHA@1236|Gammaproteobacteria,468QN@72275|Alteromonadaceae	1236|Gammaproteobacteria	P	Protein of unknown function (DUF2892)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2892
k141_5216_1	223926.28810047	3.04e-117	357.0	COG1523@1|root,COG1523@2|Bacteria,1MU19@1224|Proteobacteria,1RP6F@1236|Gammaproteobacteria,1XTF4@135623|Vibrionales	135623|Vibrionales	G	Belongs to the glycosyl hydrolase 13 family	glgX	-	3.2.1.68	ko:K01214	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R09995,R11261	-	ko00000,ko00001,ko00002,ko01000	-	CBM48,GH13	-	Alpha-amylase,CBM_48
k141_5216_2	1348635.BBJY01000001_gene2584	1.48e-108	333.0	COG0790@1|root,COG0790@2|Bacteria,1N6ZB@1224|Proteobacteria,1SYIP@1236|Gammaproteobacteria,1XU4U@135623|Vibrionales	135623|Vibrionales	S	COG0790 FOG TPR repeat, SEL1 subfamily	-	-	-	-	-	-	-	-	-	-	-	-	Sel1
k141_5216_3	55601.VANGNB10_cII0131c	2.12e-220	616.0	COG3633@1|root,COG3633@2|Bacteria,1MXE1@1224|Proteobacteria,1RP9B@1236|Gammaproteobacteria,1XSMF@135623|Vibrionales	135623|Vibrionales	E	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)	sstT	GO:0003674,GO:0005215,GO:0005310,GO:0005342,GO:0005343,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0006820,GO:0006835,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015077,GO:0015081,GO:0015291,GO:0015293,GO:0015294,GO:0015318,GO:0015370,GO:0015672,GO:0015711,GO:0015849,GO:0017153,GO:0022804,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0035725,GO:0046873,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0098655,GO:0098656,GO:0098660,GO:0098662,GO:1903825,GO:1905039	-	ko:K07862	-	-	-	-	ko00000,ko02000	2.A.23.4	-	-	SDF
k141_585_4	1408428.JNJP01000030_gene959	2.48e-154	445.0	28MVD@1|root,2ZB2Y@2|Bacteria,1R8NK@1224|Proteobacteria,42QIP@68525|delta/epsilon subdivisions,2WKTY@28221|Deltaproteobacteria,2MA65@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF4043)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4043
k141_585_9	1121441.AUCX01000014_gene513	9.55e-51	183.0	COG3170@1|root,COG3170@2|Bacteria,1N4R0@1224|Proteobacteria,42QKG@68525|delta/epsilon subdivisions,2WMF1@28221|Deltaproteobacteria,2MBE5@213115|Desulfovibrionales	28221|Deltaproteobacteria	NU	Tfp pilus assembly protein FimV	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_3232_1	1167006.UWK_00619	1.49e-203	585.0	COG0730@1|root,COG0730@2|Bacteria,1N1I6@1224|Proteobacteria,42N92@68525|delta/epsilon subdivisions,2WJT2@28221|Deltaproteobacteria,2MJ8P@213118|Desulfobacterales	28221|Deltaproteobacteria	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
k141_301_1	1224318.DT73_20970	1.73e-96	306.0	COG3002@1|root,COG3002@2|Bacteria,1MX5K@1224|Proteobacteria,1RQC2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Belongs to the UPF0753 family	-	-	-	ko:K09822	-	-	-	-	ko00000	-	-	-	DUF2309
k141_5217_1	644282.Deba_1685	2.89e-21	94.4	COG0600@1|root,COG1116@1|root,COG0600@2|Bacteria,COG1116@2|Bacteria,1MUDV@1224|Proteobacteria,42QRU@68525|delta/epsilon subdivisions,2WMNQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	ABC transporter	-	-	-	ko:K02049,ko:K15555,ko:K15600	ko00920,ko02010,map00920,map02010	M00188,M00436,M00442	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.16,3.A.1.17,3.A.1.17.2,3.A.1.17.3,3.A.1.17.6	-	-	ABC_tran
k141_5217_2	641491.DND132_0090	5.04e-32	127.0	COG0614@1|root,COG1116@1|root,COG0614@2|Bacteria,COG1116@2|Bacteria,1R6WT@1224|Proteobacteria,42Q8K@68525|delta/epsilon subdivisions,2X9WQ@28221|Deltaproteobacteria,2MC1H@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	PFAM ABC transporter related	-	-	-	ko:K02049	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	ABC_tran
k141_841_1	1121115.AXVN01000093_gene365	8.17e-88	291.0	COG1204@1|root,COG1204@2|Bacteria,1TT19@1239|Firmicutes,2494I@186801|Clostridia	186801|Clostridia	L	helicase	-	-	-	-	-	-	-	-	-	-	-	-	DEAD,Helicase_C
k141_4259_1	96561.Dole_2292	8.3e-80	258.0	COG0025@1|root,COG0569@1|root,COG0025@2|Bacteria,COG0569@2|Bacteria,1QTUE@1224|Proteobacteria,43BRM@68525|delta/epsilon subdivisions,2WM4A@28221|Deltaproteobacteria,2MHXR@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family	-	-	-	ko:K03316	-	-	-	-	ko00000	2.A.36	-	-	Na_H_Exchanger,TrkA_N
k141_4259_2	96561.Dole_2849	4.05e-69	221.0	COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,42NES@68525|delta/epsilon subdivisions,2WJ0V@28221|Deltaproteobacteria,2MHWD@213118|Desulfobacterales	28221|Deltaproteobacteria	NU	type II secretion system	pilC	-	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
k141_1550_1	1280001.BAOA01000048_gene1846	7.09e-66	206.0	COG0564@1|root,COG0564@2|Bacteria,1MVJ5@1224|Proteobacteria,1RN4N@1236|Gammaproteobacteria,1XURW@135623|Vibrionales	135623|Vibrionales	J	Responsible for synthesis of pseudouridine from uracil	rluA	GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	5.4.99.28,5.4.99.29	ko:K06177	-	-	-	-	ko00000,ko01000,ko03009,ko03016	-	-	-	PseudoU_synth_2
k141_1550_2	1219065.VPR01S_20_00440	2.65e-189	536.0	COG1914@1|root,COG1914@2|Bacteria,1MWET@1224|Proteobacteria,1RY2N@1236|Gammaproteobacteria,1XW0V@135623|Vibrionales	135623|Vibrionales	P	Mn2 and Fe2 transporters of the NRAMP family	-	-	-	-	-	-	-	-	-	-	-	-	Nramp
k141_2260_1	1122211.JMLW01000005_gene502	2.19e-47	168.0	COG0747@1|root,COG0747@2|Bacteria,1MUZH@1224|Proteobacteria,1RNES@1236|Gammaproteobacteria,1XH8S@135619|Oceanospirillales	135619|Oceanospirillales	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_5
k141_2260_2	1121396.KB892904_gene4246	6.73e-202	587.0	COG1629@1|root,COG4771@2|Bacteria,1MUC1@1224|Proteobacteria,42NGM@68525|delta/epsilon subdivisions,2WKKR@28221|Deltaproteobacteria,2MMH5@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Outer membrane protein beta-barrel family	-	-	-	ko:K16089	-	-	-	-	ko00000,ko02000	1.B.14.1,1.B.14.10	-	-	Plug,TonB_dep_Rec
k141_302_1	1453500.AT05_04700	2.25e-13	77.8	COG1960@1|root,COG1960@2|Bacteria,4NEKJ@976|Bacteroidetes,1HYD3@117743|Flavobacteriia	976|Bacteroidetes	I	acyl-CoA dehydrogenase	gcdH	-	1.3.8.6	ko:K00252	ko00071,ko00310,ko00362,ko00380,ko01100,ko01120,ko01130,map00071,map00310,map00362,map00380,map01100,map01120,map01130	M00032	R02487,R02488,R10074	RC00052,RC00156	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
k141_4651_1	104623.Ser39006_00661	3.23e-233	655.0	COG3333@1|root,COG3333@2|Bacteria,1MUKR@1224|Proteobacteria,1RMQB@1236|Gammaproteobacteria,3ZZKU@613|Serratia	1236|Gammaproteobacteria	S	Tripartite tricarboxylate transporter TctA	-	-	-	-	-	-	-	-	-	-	-	-	TctA
k141_3233_1	1121405.dsmv_0286	5.12e-146	426.0	COG0124@1|root,COG0124@2|Bacteria,1MV2K@1224|Proteobacteria,42MG0@68525|delta/epsilon subdivisions,2WJE1@28221|Deltaproteobacteria,2MI2D@213118|Desulfobacterales	28221|Deltaproteobacteria	J	TIGRFAM histidyl-tRNA synthetase	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
k141_5218_1	1136163.M565_ctg1P0200	2.45e-18	79.7	2BBNH@1|root,3256H@2|Bacteria,1QKCP@1224|Proteobacteria,1TIG6@1236|Gammaproteobacteria,1XZ2Q@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	ko:K02651	ko04112,map04112	-	-	-	ko00000,ko00001,ko02035,ko02044	-	-	-	-
k141_5218_2	945550.VISI1226_15791	5.09e-22	94.7	COG4960@1|root,COG4960@2|Bacteria,1QKFB@1224|Proteobacteria,1TIJ8@1236|Gammaproteobacteria,1XZ89@135623|Vibrionales	135623|Vibrionales	OU	COG4960 Flp pilus assembly protein, protease CpaA	-	-	3.4.23.43	ko:K02278	-	-	-	-	ko00000,ko01000,ko02035,ko02044	-	-	-	Peptidase_A24
k141_5218_3	1348635.BBJY01000008_gene1750	2.3e-21	94.0	COG0714@1|root,COG0714@2|Bacteria,1QUGB@1224|Proteobacteria,1T1Y2@1236|Gammaproteobacteria,1XSEK@135623|Vibrionales	135623|Vibrionales	S	ATPase with chaperone activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_3937_1	1238450.VIBNISOn1_1320008	4.27e-163	465.0	COG3853@1|root,COG3853@2|Bacteria,1MZ3B@1224|Proteobacteria,1RZUJ@1236|Gammaproteobacteria,1XWHW@135623|Vibrionales	135623|Vibrionales	P	Toxic anion resistance protein (TelA)	-	-	-	-	-	-	-	-	-	-	-	-	TelA
k141_3937_2	525898.Sdel_2193	0.0	1285.0	COG2972@1|root,COG5001@1|root,COG2972@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,43D0E@68525|delta/epsilon subdivisions	1224|Proteobacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF,GGDEF,HAMP,PAS_9,PocR
k141_3937_6	1116375.VEJY3_06520	4.93e-275	761.0	COG4145@1|root,COG4145@2|Bacteria,1QUAY@1224|Proteobacteria,1RP9P@1236|Gammaproteobacteria,1XSN1@135623|Vibrionales	135623|Vibrionales	H	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	panF	-	-	ko:K14392	-	-	-	-	ko00000,ko02000	2.A.21.1	-	-	SSF
k141_3937_7	1454202.PPBDW_60030___1	2.69e-34	120.0	COG3924@1|root,COG3924@2|Bacteria,1MZ8K@1224|Proteobacteria,1S8QV@1236|Gammaproteobacteria,1XYCH@135623|Vibrionales	135623|Vibrionales	S	Protein of unknown function (DUF997)	-	-	-	-	-	-	-	-	-	-	-	-	DUF997
k141_3937_8	83406.HDN1F_34080	1.34e-58	193.0	COG1051@1|root,COG1051@2|Bacteria,1QTT4@1224|Proteobacteria,1RQ35@1236|Gammaproteobacteria	1236|Gammaproteobacteria	F	COG1051 ADP-ribose pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
k141_3937_9	349521.HCH_06993	3.37e-146	425.0	COG1051@1|root,COG1056@1|root,COG1051@2|Bacteria,COG1056@2|Bacteria,1MWNH@1224|Proteobacteria,1RY71@1236|Gammaproteobacteria,1XINJ@135619|Oceanospirillales	135619|Oceanospirillales	FH	Bifunctional nicotinamide mononucleotide adenylyltransferase ADP-ribose pyrophosphatase	-	-	2.7.7.1	ko:K13522	ko00760,ko01100,map00760,map01100	-	R00137,R03005	RC00002	ko00000,ko00001,ko01000	-	-	-	CTP_transf_like,NUDIX
k141_3937_10	1121935.AQXX01000113_gene1411	1.49e-235	659.0	COG1488@1|root,COG1488@2|Bacteria,1MWA2@1224|Proteobacteria,1RPPA@1236|Gammaproteobacteria,1XN1B@135619|Oceanospirillales	135619|Oceanospirillales	H	Nicotinate phosphoribosyltransferase (NAPRTase) family	-	-	2.4.2.12	ko:K03462	ko00760,ko01100,ko04621,map00760,map01100,map04621	-	R01271	RC00033	ko00000,ko00001,ko01000	-	-	-	NAPRTase
k141_3937_11	203122.Sde_3065	7.55e-84	252.0	COG0494@1|root,COG0494@2|Bacteria,1PC5J@1224|Proteobacteria,1S267@1236|Gammaproteobacteria,466TG@72275|Alteromonadaceae	1236|Gammaproteobacteria	L	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
k141_3937_12	1190603.AJYD01000025_gene441	4.39e-178	508.0	COG1167@1|root,COG1167@2|Bacteria,1MV6F@1224|Proteobacteria,1RNDN@1236|Gammaproteobacteria,1Y2KC@135623|Vibrionales	135623|Vibrionales	EK	Alanine-glyoxylate amino-transferase	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
k141_3937_13	1056512.D515_04026	1.39e-142	410.0	COG2207@1|root,COG3449@1|root,COG2207@2|Bacteria,COG3449@2|Bacteria,1MWTF@1224|Proteobacteria,1RMKE@1236|Gammaproteobacteria,1XT8F@135623|Vibrionales	135623|Vibrionales	K	Bacterial transcription activator, effector binding domain	-	-	-	ko:K13652	-	-	-	-	ko00000,ko03000	-	-	-	GyrI-like,HTH_18
k141_3937_14	644801.Psest_0101	5.65e-134	385.0	COG4221@1|root,COG4221@2|Bacteria,1MUF8@1224|Proteobacteria,1RMKM@1236|Gammaproteobacteria,1Z187@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	sdh	-	1.1.1.276,1.1.1.313,1.1.1.381	ko:K05886,ko:K15373,ko:K16066	ko00240,ko00260,ko00430,ko01100,map00240,map00260,map00430,map01100	-	R02600,R09289,R10851,R10852	RC00087,RC00525,RC03288	ko00000,ko00001,ko01000	-	-	-	adh_short
k141_3937_15	675815.VOA_001589	1.9e-48	158.0	2E4HY@1|root,33HKA@2|Bacteria,1NIGQ@1224|Proteobacteria,1SHKJ@1236|Gammaproteobacteria,1XXT7@135623|Vibrionales	135623|Vibrionales	S	Late competence development protein ComFB	-	-	-	-	-	-	-	-	-	-	-	-	ComFB
k141_3937_16	1027273.GZ77_16925	2.5e-28	105.0	COG5453@1|root,COG5453@2|Bacteria,1N7WA@1224|Proteobacteria,1SE7G@1236|Gammaproteobacteria,1XMRW@135619|Oceanospirillales	135619|Oceanospirillales	S	Transcriptional activator HlyU	-	-	-	-	-	-	-	-	-	-	-	-	HlyU
k141_3937_17	1348635.BBJY01000014_gene801	1.22e-304	838.0	COG3288@1|root,COG3288@2|Bacteria,1MVXU@1224|Proteobacteria,1RN23@1236|Gammaproteobacteria,1XU8J@135623|Vibrionales	135623|Vibrionales	C	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane	pntA	-	1.6.1.2	ko:K00324	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N,PNTB_4TM
k141_3937_18	29495.EA26_11420	4.04e-279	769.0	COG1282@1|root,COG1282@2|Bacteria,1MUP4@1224|Proteobacteria,1RMR4@1236|Gammaproteobacteria,1XT5B@135623|Vibrionales	135623|Vibrionales	C	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane	pntB	-	1.6.1.2	ko:K00325	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	PNTB
k141_3937_19	1219065.VPR01S_07_00970	7.77e-260	722.0	COG0642@1|root,COG0642@2|Bacteria,1R9IX@1224|Proteobacteria,1SMI3@1236|Gammaproteobacteria,1XTIK@135623|Vibrionales	135623|Vibrionales	T	COG0642 Signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	DUF3404,HATPase_c,HisKA
k141_3937_20	675813.VIB_002172	1.72e-138	393.0	COG0745@1|root,COG0745@2|Bacteria,1N7TJ@1224|Proteobacteria,1S21N@1236|Gammaproteobacteria,1XSJI@135623|Vibrionales	135623|Vibrionales	K	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
k141_3937_21	1219065.VPR01S_07_00990	6.55e-114	337.0	2BTFF@1|root,32NMR@2|Bacteria,1QJBY@1224|Proteobacteria,1THAZ@1236|Gammaproteobacteria,1XSXM@135623|Vibrionales	135623|Vibrionales	S	Protein of unknown function (DUF2861)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2861
k141_3937_22	243277.VC_A0568	1.28e-142	416.0	28IW1@1|root,2Z8UB@2|Bacteria,1N1QM@1224|Proteobacteria,1RR0J@1236|Gammaproteobacteria,1XSR0@135623|Vibrionales	135623|Vibrionales	S	F plasmid transfer operon, TraF, protein	-	-	-	-	-	-	-	-	-	-	-	-	TraF_2
k141_3937_23	945543.VIBR0546_01536	4.38e-13	63.5	COG3140@1|root,COG3140@2|Bacteria,1N89H@1224|Proteobacteria,1SCHP@1236|Gammaproteobacteria,1XZEF@135623|Vibrionales	135623|Vibrionales	S	Belongs to the UPF0181 family	-	-	-	ko:K09917	-	-	-	-	ko00000	-	-	-	UPF0181
k141_3937_24	1348635.BBJY01000005_gene3164	3.8e-77	233.0	COG0783@1|root,COG0783@2|Bacteria,1RAC5@1224|Proteobacteria,1S3UH@1236|Gammaproteobacteria,1XWX7@135623|Vibrionales	135623|Vibrionales	P	Belongs to the Dps family	dps	-	-	ko:K04047	-	-	-	-	ko00000,ko03036	-	-	-	Ferritin
k141_3937_26	373994.Riv7116_5179	3.17e-52	201.0	COG3177@1|root,COG3177@2|Bacteria,1G79A@1117|Cyanobacteria,1HSMG@1161|Nostocales	1117|Cyanobacteria	S	Domain of unknown function (DUF4157)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4157
k141_3937_28	398512.JQKC01000024_gene3225	4.61e-49	159.0	COG4974@1|root,COG4974@2|Bacteria,1TR57@1239|Firmicutes,24ACW@186801|Clostridia	186801|Clostridia	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
k141_3937_30	1224318.DT73_22525	1.32e-72	222.0	COG3177@1|root,COG3177@2|Bacteria,1RJSD@1224|Proteobacteria,1S9AR@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Domain of unknown function (DUF4157)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4157
k141_3937_31	1224318.DT73_22520	3.38e-294	807.0	COG0464@1|root,COG0464@2|Bacteria,1NF48@1224|Proteobacteria,1RQNE@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	protein of Photorhabdus and some similarities with C-terminal region of AAA family ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA
k141_1551_2	717231.Flexsi_1733	7.77e-12	65.5	COG1538@1|root,COG1538@2|Bacteria,2GFNB@200930|Deferribacteres	200930|Deferribacteres	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
k141_586_1	590409.Dd586_4044	4.72e-05	48.9	COG0742@1|root,COG0742@2|Bacteria,1MXKW@1224|Proteobacteria,1RN21@1236|Gammaproteobacteria,2JCWV@204037|Dickeya	1236|Gammaproteobacteria	L	Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle	rsmD	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0008990,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0052913,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.171	ko:K08316	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Cons_hypoth95
k141_586_2	96561.Dole_2741	3.45e-70	216.0	COG0669@1|root,COG0669@2|Bacteria,1RD9F@1224|Proteobacteria,42RJQ@68525|delta/epsilon subdivisions,2WNDS@28221|Deltaproteobacteria,2MJTB@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	GO:0003674,GO:0003824,GO:0004595,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
k141_586_3	1304885.AUEY01000022_gene3407	5.05e-119	350.0	COG0583@1|root,COG0583@2|Bacteria,1MWVU@1224|Proteobacteria,42PMQ@68525|delta/epsilon subdivisions,2WKB8@28221|Deltaproteobacteria,2MIF9@213118|Desulfobacterales	28221|Deltaproteobacteria	K	Transcriptional regulator, LysR	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
k141_1937_4	55601.VANGNB10_cII0544c	6.27e-109	319.0	COG1011@1|root,COG1011@2|Bacteria,1MVF8@1224|Proteobacteria,1RMK3@1236|Gammaproteobacteria,1XSVE@135623|Vibrionales	135623|Vibrionales	S	hydrolase (HAD superfamily)	yjjG	-	3.1.3.5	ko:K08723	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
k141_1937_6	319224.Sputcn32_0181	2.65e-31	112.0	COG4737@1|root,COG4737@2|Bacteria,1N7N5@1224|Proteobacteria,1S7H6@1236|Gammaproteobacteria,2QDYI@267890|Shewanellaceae	1236|Gammaproteobacteria	S	RelE toxin of RelE / RelB toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	RelE
k141_1937_7	1515746.HR45_13580	4.15e-50	160.0	COG2944@1|root,COG2944@2|Bacteria,1N155@1224|Proteobacteria,1S8UJ@1236|Gammaproteobacteria,2QE1V@267890|Shewanellaceae	1236|Gammaproteobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,HTH_31
k141_3009_2	985665.HPL003_17425	5.37e-13	63.2	COG4895@1|root,COG4895@2|Bacteria,1VEG3@1239|Firmicutes,4HNJA@91061|Bacilli,26ZRV@186822|Paenibacillaceae	91061|Bacilli	S	Uncharacterized conserved protein (DUF2196)	ywbE	-	-	-	-	-	-	-	-	-	-	-	DUF2196
k141_1678_1	675817.VDA_002532	6.61e-70	228.0	COG3203@1|root,COG3203@2|Bacteria,1NA7U@1224|Proteobacteria,1RPXP@1236|Gammaproteobacteria,1XUJ9@135623|Vibrionales	135623|Vibrionales	M	COG3203 Outer membrane protein (porin)	ompH	GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Porin_4
k141_1678_2	1517681.HW45_08100	1.01e-14	77.8	COG3110@1|root,COG3110@2|Bacteria,1NMI8@1224|Proteobacteria,1SCVE@1236|Gammaproteobacteria,1XTHD@135623|Vibrionales	135623|Vibrionales	S	Belongs to the UPF0319 family	-	-	-	ko:K09909	-	-	-	-	ko00000	-	-	-	DUF2057
k141_1678_3	28229.ND2E_3373	1.08e-69	233.0	COG3434@1|root,COG3434@2|Bacteria,1MVW1@1224|Proteobacteria,1RS25@1236|Gammaproteobacteria,2Q7XX@267889|Colwelliaceae	1236|Gammaproteobacteria	T	HDOD domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,HDOD
k141_1678_4	1042376.AFPK01000065_gene2819	1.34e-35	127.0	COG3012@1|root,COG3012@2|Bacteria,4NT83@976|Bacteroidetes,1I2WK@117743|Flavobacteriia,4079B@61432|unclassified Flavobacteriaceae	976|Bacteroidetes	S	Preprotein translocase subunit SecA	-	-	-	ko:K09858	-	-	-	-	ko00000	-	-	-	SEC-C
k141_1678_5	945543.VIBR0546_06442	3.89e-137	404.0	COG3434@1|root,COG3434@2|Bacteria,1MVW1@1224|Proteobacteria,1RS25@1236|Gammaproteobacteria,1XTJ5@135623|Vibrionales	135623|Vibrionales	T	signal transduction protein containing EAL and modified HD-GYP domains	-	-	-	-	-	-	-	-	-	-	-	-	EAL,HDOD
k141_2708_1	392500.Swoo_2508	1.83e-82	294.0	COG3209@1|root,COG3209@2|Bacteria,1MVV1@1224|Proteobacteria,1SKYM@1236|Gammaproteobacteria,2QEJM@267890|Shewanellaceae	1236|Gammaproteobacteria	M	RHS protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF4150,PAAR_motif,RHS,RHS_repeat,Tox-HNH-EHHH
k141_3010_1	443144.GM21_3104	1.01e-07	55.1	COG4585@1|root,COG4585@2|Bacteria,1MWPN@1224|Proteobacteria,42SJA@68525|delta/epsilon subdivisions,2WPP4@28221|Deltaproteobacteria,43VIA@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	histidine kinase, dimerisation and phosphoacceptor region	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA_3,PAS,PAS_4,PAS_8,PAS_9,Response_reg
k141_3010_2	525897.Dbac_0541	5.36e-43	148.0	COG1986@1|root,COG1986@2|Bacteria,1Q6S4@1224|Proteobacteria,433PP@68525|delta/epsilon subdivisions,2WX89@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	Protein of unknown function DUF84	-	-	-	-	-	-	-	-	-	-	-	-	NTPase_I-T
k141_3010_3	324602.Caur_2965	8.74e-71	226.0	COG1806@1|root,COG1806@2|Bacteria,2G8E0@200795|Chloroflexi	200795|Chloroflexi	S	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation	-	-	2.7.11.33,2.7.4.28	ko:K09773	-	-	-	-	ko00000,ko01000	-	-	-	Kinase-PPPase
k141_1017_1	1123511.KB905839_gene356	3.37e-221	625.0	COG3534@1|root,COG3534@2|Bacteria,1TRY9@1239|Firmicutes,4H6IB@909932|Negativicutes	909932|Negativicutes	G	Alpha-L-arabinofuranosidase C-terminus	-	-	3.2.1.55	ko:K01209	ko00520,map00520	-	R01762	-	ko00000,ko00001,ko01000	-	GH51	-	Alpha-L-AF_C
k141_1017_2	1214065.BAGV01000014_gene3105	1.07e-120	359.0	COG2038@1|root,COG2038@2|Bacteria,1MVAM@1224|Proteobacteria,1RNPV@1236|Gammaproteobacteria	1236|Gammaproteobacteria	F	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB)	cobT	GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008939,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0017144,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042364,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.4.2.21	ko:K00768	ko00860,ko01100,map00860,map01100	M00122	R04148	RC00033,RC00063	ko00000,ko00001,ko00002,ko01000	-	-	-	DBI_PRT
k141_1017_3	1111728.ATYS01000003_gene1838	8.68e-52	173.0	COG0368@1|root,COG0368@2|Bacteria,1RHCC@1224|Proteobacteria,1S4TE@1236|Gammaproteobacteria	1236|Gammaproteobacteria	H	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate	cobS	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008818,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0017144,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042364,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.8.26	ko:K02233	ko00860,ko01100,map00860,map01100	M00122	R05223,R11174	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	iECH74115_1262.ECH74115_2837,iECO103_1326.ECO103_2453,iECSP_1301.ECSP_2657,iECs_1301.ECs2787,iG2583_1286.G2583_2502,iUTI89_1310.UTI89_C2230,iZ_1308.Z3152,ic_1306.c2478	CobS
k141_1679_2	945543.VIBR0546_11752	2.31e-61	196.0	COG0705@1|root,COG0705@2|Bacteria,1RANX@1224|Proteobacteria,1S2I5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Rhomboid family	-	-	3.4.21.105	ko:K19225	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Rhomboid
k141_1018_1	406818.XBJ1_3704	1.48e-11	60.8	2DRA2@1|root,33AVQ@2|Bacteria,1NKZA@1224|Proteobacteria,1SH2Z@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_1019_1	1208321.D104_03040	1.03e-93	291.0	COG0747@1|root,COG0747@2|Bacteria,1MUZH@1224|Proteobacteria,1RNES@1236|Gammaproteobacteria,1XH6Y@135619|Oceanospirillales	135619|Oceanospirillales	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
k141_1680_1	1304885.AUEY01000024_gene2717	3.38e-234	667.0	COG1960@1|root,COG1960@2|Bacteria,1MU20@1224|Proteobacteria,42NSP@68525|delta/epsilon subdivisions,2WMAD@28221|Deltaproteobacteria,2MHRF@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM Acyl-CoA dehydrogenase N terminal	-	-	1.3.8.1	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	-	R01175,R01178,R02661,R03172,R04751	RC00052,RC00068,RC00076,RC00120,RC00148	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_C,Acyl-CoA_dh_M,Acyl-CoA_dh_N,AcylCoA_DH_N
k141_1680_2	1304885.AUEY01000024_gene2718	7.52e-17	78.2	COG1024@1|root,COG1024@2|Bacteria,1MXHV@1224|Proteobacteria,42QU2@68525|delta/epsilon subdivisions,2WMSF@28221|Deltaproteobacteria,2MJJF@213118|Desulfobacterales	28221|Deltaproteobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
k141_2709_2	1577887.JSYG01000020_gene1532	1.32e-194	599.0	COG3209@1|root,COG3209@2|Bacteria,1MVV1@1224|Proteobacteria,1SKYM@1236|Gammaproteobacteria,2JEQ6@204037|Dickeya	1236|Gammaproteobacteria	M	TIGRFAM YD repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	RHS,RHS_repeat,Tox-HNH-EHHH
k141_3011_2	316275.VSAL_I0611	4.69e-19	84.3	COG3050@1|root,COG3050@2|Bacteria,1RH2F@1224|Proteobacteria,1S634@1236|Gammaproteobacteria,1XYDF@135623|Vibrionales	135623|Vibrionales	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is	holD	-	2.7.7.7	ko:K02344	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_III_psi
k141_3011_3	1280001.BAOA01000021_gene730	5.24e-231	642.0	COG1004@1|root,COG1004@2|Bacteria,1MW5U@1224|Proteobacteria,1RMVW@1236|Gammaproteobacteria,1XTZN@135623|Vibrionales	135623|Vibrionales	C	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	ugd	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
k141_3011_4	575788.VS_2468	2.75e-55	177.0	COG0454@1|root,COG0456@2|Bacteria,1RIE6@1224|Proteobacteria,1S9G0@1236|Gammaproteobacteria,1XXEY@135623|Vibrionales	135623|Vibrionales	K	This enzyme acetylates the N-terminal alanine of ribosomal protein S18	rimI	-	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1,Acetyltransf_10
k141_3011_5	1187848.AJYQ01000125_gene2540	4.72e-11	67.8	COG2148@1|root,COG2148@2|Bacteria,1MV6W@1224|Proteobacteria,1RMMN@1236|Gammaproteobacteria,1XTWQ@135623|Vibrionales	135623|Vibrionales	M	COG2148 Sugar transferases involved in lipopolysaccharide synthesis	-	-	-	ko:K03606	ko05111,map05111	-	-	-	ko00000,ko00001	-	-	-	Bac_transf,CoA_binding_3
k141_2710_1	78398.KS43_08975	3.44e-66	206.0	COG0693@1|root,COG0693@2|Bacteria,1MVTT@1224|Proteobacteria,1RPVK@1236|Gammaproteobacteria,1MQUX@122277|Pectobacterium	1236|Gammaproteobacteria	S	DJ-1/PfpI family	-	-	-	-	-	-	-	-	-	-	-	-	DJ-1_PfpI
k141_2710_2	1441629.PCH70_14060	3.79e-229	644.0	COG1012@1|root,COG1012@2|Bacteria,1MVGW@1224|Proteobacteria,1RN53@1236|Gammaproteobacteria,1Z9UE@136849|Pseudomonas syringae group	1236|Gammaproteobacteria	C	Aldehyde dehydrogenase family	-	-	1.2.1.68	ko:K00154	-	-	-	-	ko00000,ko01000	-	-	-	Aldedh
k141_2710_3	1238450.VIBNISOn1_1520046	2.52e-121	355.0	COG2130@1|root,COG2130@2|Bacteria,1MUC2@1224|Proteobacteria,1RNGM@1236|Gammaproteobacteria,1XT12@135623|Vibrionales	135623|Vibrionales	S	NADP-dependent oxidoreductases	-	-	-	ko:K07119	-	-	-	-	ko00000	-	-	-	ADH_N_2,ADH_zinc_N
k141_1681_1	1005999.GLGR_0490	9.9e-197	549.0	COG0111@1|root,COG0111@2|Bacteria,1NU4B@1224|Proteobacteria,1S3W6@1236|Gammaproteobacteria	1236|Gammaproteobacteria	EH	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family	-	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
k141_3013_1	1304885.AUEY01000001_gene3262	1.6e-211	625.0	COG0643@1|root,COG0643@2|Bacteria,1MUAG@1224|Proteobacteria,42M6Q@68525|delta/epsilon subdivisions,2WJ5U@28221|Deltaproteobacteria,2MIXJ@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Signal transducing histidine kinase, homodimeric	-	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt,Response_reg
k141_2711_1	1116375.VEJY3_19406	3.71e-133	384.0	COG0702@1|root,COG0702@2|Bacteria,1MW44@1224|Proteobacteria,1RPD9@1236|Gammaproteobacteria,1XY9C@135623|Vibrionales	135623|Vibrionales	GM	NmrA-like family	-	-	1.6.5.2	ko:K19267	ko00130,ko01110,map00130,map01110	-	R02964,R03643,R03816	RC00819	ko00000,ko00001,ko01000	-	-	-	NAD_binding_10,NmrA
k141_2711_2	1116375.VEJY3_23496	1.7e-43	141.0	COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,1S9KC@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	'Cold-shock' DNA-binding domain	cspA	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
k141_1020_1	1219065.VPR01S_05_02750	1.82e-79	238.0	COG0454@1|root,COG0456@2|Bacteria,1MZQ5@1224|Proteobacteria,1S45R@1236|Gammaproteobacteria,1XXGD@135623|Vibrionales	135623|Vibrionales	K	Acetyltransferase (GNAT) domain	-	-	-	ko:K03826	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_10,Acetyltransf_7
k141_1020_2	469595.CSAG_00127	3.98e-126	367.0	COG1414@1|root,COG1414@2|Bacteria,1QRZN@1224|Proteobacteria,1RYF9@1236|Gammaproteobacteria,3WZ13@544|Citrobacter	1236|Gammaproteobacteria	K	helix_turn_helix isocitrate lyase regulation	mhpR	GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141	-	ko:K05818	-	-	-	-	ko00000,ko03000	-	-	-	HTH_IclR,IclR
k141_1020_3	1219065.VPR01S_05_01820	7.08e-60	187.0	COG1765@1|root,COG1765@2|Bacteria,1RCZW@1224|Proteobacteria,1S3XF@1236|Gammaproteobacteria,1XWXE@135623|Vibrionales	135623|Vibrionales	O	redox protein, regulator of disulfide bond formation	yhfA	-	-	ko:K07397	-	-	-	-	ko00000	-	-	-	OsmC
k141_1020_4	345073.VC395_0558	2.45e-214	598.0	COG1118@1|root,COG1118@2|Bacteria,1QTTT@1224|Proteobacteria,1RN1B@1236|Gammaproteobacteria,1XW1S@135623|Vibrionales	135623|Vibrionales	P	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system	cysA	GO:0003674,GO:0003824,GO:0005215,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008272,GO:0008509,GO:0015075,GO:0015103,GO:0015116,GO:0015318,GO:0015399,GO:0015405,GO:0015419,GO:0015698,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0034220,GO:0042623,GO:0042626,GO:0043225,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0072348,GO:0098656,GO:0098660,GO:0098661,GO:0099133,GO:1901682,GO:1902358	3.6.3.25	ko:K02045	ko00920,ko02010,map00920,map02010	M00185	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.6.1,3.A.1.6.3	-	-	ABC_tran,TOBE_3
k141_1020_5	1348635.BBJY01000002_gene3632	3.29e-161	456.0	COG4208@1|root,COG4208@2|Bacteria,1MV8X@1224|Proteobacteria,1RNZK@1236|Gammaproteobacteria,1XVTH@135623|Vibrionales	135623|Vibrionales	P	Binding-protein-dependent transport system inner membrane component	cysW	-	-	ko:K02047	ko00920,ko02010,map00920,map02010	M00185	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.1,3.A.1.6.3	-	-	BPD_transp_1
k141_1020_6	1348635.BBJY01000002_gene3633	2.52e-160	454.0	COG0555@1|root,COG0555@2|Bacteria,1QTTU@1224|Proteobacteria,1RS0W@1236|Gammaproteobacteria,1XVVN@135623|Vibrionales	135623|Vibrionales	P	Binding-protein-dependent transport system inner membrane component	cysT	-	-	ko:K02046	ko00920,ko02010,map00920,map02010	M00185	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.1,3.A.1.6.3	-	-	BPD_transp_1
k141_1020_7	319224.Sputcn32_1005	2.67e-93	281.0	COG4150@1|root,COG4150@2|Bacteria,1QTZY@1224|Proteobacteria,1T1JH@1236|Gammaproteobacteria,2Q9VI@267890|Shewanellaceae	1236|Gammaproteobacteria	P	TIGRFAM sulfate ABC transporter, periplasmic sulfate-binding protein	cysP	GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006790,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008152,GO:0008272,GO:0009987,GO:0015698,GO:0015709,GO:0030288,GO:0030313,GO:0031975,GO:0036173,GO:0042597,GO:0043167,GO:0043168,GO:0043199,GO:0044237,GO:0044464,GO:0051179,GO:0051234,GO:0072348,GO:1901681	-	ko:K02048	ko00920,ko02010,map00920,map02010	M00185	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.1,3.A.1.6.3	-	iECIAI39_1322.ECIAI39_2570	SBP_bac_11
k141_2714_2	247639.MGP2080_00490	3.1e-57	193.0	COG2040@1|root,COG2040@2|Bacteria,1QU2A@1224|Proteobacteria,1RS8M@1236|Gammaproteobacteria	1236|Gammaproteobacteria	H	homocysteine	-	-	-	-	-	-	-	-	-	-	-	-	S-methyl_trans
k141_3014_2	644282.Deba_0906	3.07e-14	73.2	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	two component, sigma54 specific, transcriptional regulator, Fis family	fgrM	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
k141_2715_1	1219076.N646_3659	3.33e-05	46.6	COG0845@1|root,COG0845@2|Bacteria,1MU8D@1224|Proteobacteria,1RN0E@1236|Gammaproteobacteria,1XUQG@135623|Vibrionales	135623|Vibrionales	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K13888	-	M00709	-	-	ko00000,ko00002,ko02000	8.A.1	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
k141_1021_1	526222.Desal_0192	1.88e-16	81.6	COG0247@1|root,COG0247@2|Bacteria,1NKKI@1224|Proteobacteria,42NPC@68525|delta/epsilon subdivisions,2WJ4N@28221|Deltaproteobacteria,2MH9U@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	Cysteine-rich domain	-	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_17,Fer4_8,SNARE_assoc
k141_3015_1	675813.VIB_001501	3.82e-88	264.0	COG2834@1|root,COG2834@2|Bacteria,1PXDV@1224|Proteobacteria,1S9FW@1236|Gammaproteobacteria,1XU2P@135623|Vibrionales	135623|Vibrionales	M	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)	lolA	GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705	-	ko:K03634	-	-	-	-	ko00000	-	-	-	LolA
k141_5389_27	536227.CcarbDRAFT_4777	1.33e-121	352.0	COG2872@1|root,COG2872@2|Bacteria,1UHS6@1239|Firmicutes,24AK0@186801|Clostridia,36GRN@31979|Clostridiaceae	186801|Clostridia	S	Threonyl alanyl tRNA synthetase SAD	-	-	-	ko:K07050	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA-synt_2c,tRNA_SAD
k141_5389_28	349161.Dred_0870	7.37e-260	731.0	COG0497@1|root,COG3593@1|root,COG0497@2|Bacteria,COG3593@2|Bacteria,1VCSI@1239|Firmicutes	1239|Firmicutes	L	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_15,AAA_21,AAA_29
k141_5389_29	1216932.CM240_0842	3.6e-127	385.0	COG3066@1|root,COG3066@2|Bacteria,1TS3J@1239|Firmicutes,249BA@186801|Clostridia,36H6K@31979|Clostridiaceae	186801|Clostridia	L	DNA mismatch repair enzyme MutH	-	-	-	-	-	-	-	-	-	-	-	-	MutH
k141_5389_30	1216932.CM240_0841	2.11e-192	545.0	COG0270@1|root,COG0270@2|Bacteria,1TS3G@1239|Firmicutes,249Q9@186801|Clostridia,36GET@31979|Clostridiaceae	186801|Clostridia	H	PFAM C-5 cytosine-specific DNA methylase	-	-	2.1.1.37	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	M00035	R04858	RC00003,RC00332	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_methylase
k141_5390_1	1121897.AUGO01000001_gene1318	6.14e-08	65.1	COG0666@1|root,COG0666@2|Bacteria,4P0G9@976|Bacteroidetes,1ICVC@117743|Flavobacteriia,2NV7F@237|Flavobacterium	976|Bacteroidetes	S	Ankyrin repeat	-	-	-	-	-	-	-	-	-	-	-	-	Ank_2,Ank_4
k141_5391_1	1121447.JONL01000005_gene1437	8.65e-59	206.0	COG2199@1|root,COG3452@1|root,COG2199@2|Bacteria,COG3452@2|Bacteria,1NV1F@1224|Proteobacteria,43D18@68525|delta/epsilon subdivisions,2X893@28221|Deltaproteobacteria,2MHDP@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	CHASE	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,GGDEF,PAS_3
k141_5392_1	469381.Dpep_1221	2.14e-09	67.0	COG2199@1|root,COG3706@2|Bacteria,3TBCU@508458|Synergistetes	508458|Synergistetes	T	PFAM GGDEF domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
k141_5393_1	648996.Theam_0543	2.31e-85	270.0	COG2067@1|root,COG2067@2|Bacteria,2G47R@200783|Aquificae	200783|Aquificae	I	Outer membrane protein transport protein (OMPP1/FadL/TodX)	-	-	-	ko:K06076	-	-	-	-	ko00000,ko02000	1.B.9	-	-	Toluene_X
k141_5394_1	525897.Dbac_1888	1.19e-92	288.0	COG1292@1|root,COG1292@2|Bacteria,1MV0K@1224|Proteobacteria,42N6Q@68525|delta/epsilon subdivisions,2WJVG@28221|Deltaproteobacteria,2M7XM@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	Belongs to the BCCT transporter (TC 2.A.15) family	-	-	-	ko:K02168,ko:K03451	-	-	-	-	ko00000,ko02000	2.A.15,2.A.15.1.3,2.A.15.1.4	-	-	BCCT
k141_5395_1	1304885.AUEY01000045_gene255	3.33e-14	79.7	COG3437@1|root,COG4191@1|root,COG3437@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42M1R@68525|delta/epsilon subdivisions,2WK3J@28221|Deltaproteobacteria,2MI5F@213118|Desulfobacterales	28221|Deltaproteobacteria	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
k141_5396_1	29495.EA26_07820	3.84e-21	93.2	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,1RPCU@1236|Gammaproteobacteria,1XT00@135623|Vibrionales	135623|Vibrionales	S	COG0488 ATPase components of ABC transporters with duplicated ATPase domains	uup	-	-	ko:K15738	-	-	-	-	ko00000,ko02000	3.A.1.120.6	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn,MMR_HSR1
k141_5396_2	1116375.VEJY3_07570	2.59e-16	85.1	COG5563@1|root,COG5563@2|Bacteria,1R4Q6@1224|Proteobacteria,1T1XK@1236|Gammaproteobacteria,1XTW4@135623|Vibrionales	135623|Vibrionales	S	Protein of unknown function (DUF3466)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3466
k141_5397_1	1051646.VITU9109_24610	2.66e-91	275.0	COG2207@1|root,COG2207@2|Bacteria,1R46K@1224|Proteobacteria,1RNCY@1236|Gammaproteobacteria,1XV7U@135623|Vibrionales	135623|Vibrionales	K	AraC-like ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18,HTH_AraC
k141_5397_2	1051646.VITU9109_24615	2.15e-94	280.0	COG1280@1|root,COG1280@2|Bacteria,1MYQ6@1224|Proteobacteria,1S7GH@1236|Gammaproteobacteria,1XXF7@135623|Vibrionales	135623|Vibrionales	E	LysE type translocator	-	-	-	-	-	-	-	-	-	-	-	-	LysE
k141_5397_3	675806.VII_000100	3.79e-75	236.0	COG3037@1|root,COG3037@2|Bacteria,1MXCA@1224|Proteobacteria,1RQTD@1236|Gammaproteobacteria,1XUHQ@135623|Vibrionales	135623|Vibrionales	S	PTS system sugar-specific permease component	ulaA	-	-	ko:K03475	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	M00283,M00550	R07671	RC00017,RC03206	ko00000,ko00001,ko00002,ko02000	4.A.7.1	-	-	EIIC-GAT
k141_5399_1	158190.SpiGrapes_1879	2.12e-21	92.8	COG1760@1|root,COG1760@2|Bacteria,2J6H3@203691|Spirochaetes	203691|Spirochaetes	E	L-serine dehydratase, iron-sulfur-dependent	sdaA	-	4.3.1.17	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	-	R00220,R00590	RC00331,RC02600	ko00000,ko00001,ko01000	-	-	-	SDH_alpha,SDH_beta
k141_5399_2	1121451.DESAM_21130	5.69e-70	223.0	COG0631@1|root,COG0631@2|Bacteria,1R84Y@1224|Proteobacteria,42MVE@68525|delta/epsilon subdivisions,2WK9T@28221|Deltaproteobacteria,2MAS9@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	Protein phosphatase 2C	-	-	-	-	-	-	-	-	-	-	-	-	PP2C_2
k141_5400_1	338963.Pcar_2914	7.73e-25	110.0	COG0210@1|root,COG0210@2|Bacteria,1QZ5U@1224|Proteobacteria,43CGG@68525|delta/epsilon subdivisions,2X7RM@28221|Deltaproteobacteria,43UHZ@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	UvrD-like helicase C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_19,UvrD_C_2
k141_5401_1	1121396.KB893106_gene1835	6.55e-241	682.0	COG1164@1|root,COG1164@2|Bacteria,1MXAC@1224|Proteobacteria,42NAD@68525|delta/epsilon subdivisions,2WKEY@28221|Deltaproteobacteria,2MKEW@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Oligopeptidase F	pepF	-	-	ko:K08602	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3,Peptidase_M3_N
k141_5402_3	857087.Metme_2492	2.75e-133	389.0	COG3547@1|root,COG3547@2|Bacteria,1MUER@1224|Proteobacteria,1RMAQ@1236|Gammaproteobacteria,1XG8U@135618|Methylococcales	135618|Methylococcales	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k141_5403_1	1232437.KL662014_gene1313	2.71e-41	161.0	COG2204@1|root,COG3852@1|root,COG4191@1|root,COG2204@2|Bacteria,COG3852@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MC4@68525|delta/epsilon subdivisions,2WIZU@28221|Deltaproteobacteria,2MJ29@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	ABC_sub_bind,GAF_2,HATPase_c,HisKA,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg,dCache_3,sCache_2
k141_5404_1	29495.EA26_19270	1.71e-209	585.0	COG5433@1|root,COG5433@2|Bacteria,1MXB5@1224|Proteobacteria,1SR4G@1236|Gammaproteobacteria,1Y0TY@135623|Vibrionales	135623|Vibrionales	L	DDE_Tnp_1-associated	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_assoc
k141_5405_1	1265505.ATUG01000003_gene528	3.04e-116	360.0	COG1148@1|root,COG1148@2|Bacteria,1QUM4@1224|Proteobacteria,42MPP@68525|delta/epsilon subdivisions,2WJ3U@28221|Deltaproteobacteria,2MJ2D@213118|Desulfobacterales	28221|Deltaproteobacteria	C	FAD binding domain	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_7,Pyr_redox_2
k141_5406_1	1265505.ATUG01000001_gene2925	4.76e-114	343.0	COG0119@1|root,COG0119@2|Bacteria,1MUNQ@1224|Proteobacteria,42MSP@68525|delta/epsilon subdivisions,2WIUZ@28221|Deltaproteobacteria,2MHS6@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)	leuA	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
k141_5407_2	1123487.KB892841_gene4254	9.22e-10	60.5	COG0265@1|root,COG0265@2|Bacteria,1RDHW@1224|Proteobacteria,2VRY7@28216|Betaproteobacteria,2KZ9R@206389|Rhodocyclales	206389|Rhodocyclales	O	Trypsin-like peptidase domain	-	-	-	-	-	-	-	-	-	-	-	-	Trypsin_2
k141_5410_1	1410624.JNKK01000005_gene254	1.61e-13	75.9	COG1609@1|root,COG1609@2|Bacteria,1TSRM@1239|Firmicutes,24BFS@186801|Clostridia,27J9H@186928|unclassified Lachnospiraceae	186801|Clostridia	K	helix_turn _helix lactose operon repressor	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_4
k141_5411_1	1116375.VEJY3_07805	1.04e-102	321.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RSAR@1236|Gammaproteobacteria,1Y0DG@135623|Vibrionales	135623|Vibrionales	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
k141_5411_2	742733.HMPREF9469_03638	4.8e-10	61.2	COG1940@1|root,COG1940@2|Bacteria,1TRT1@1239|Firmicutes,24A9E@186801|Clostridia	186801|Clostridia	GK	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	HTH_24,ROK
k141_5413_1	1230342.CTM_13558	1.33e-204	574.0	COG1473@1|root,COG1473@2|Bacteria,1TPD7@1239|Firmicutes,248AH@186801|Clostridia,36DRG@31979|Clostridiaceae	186801|Clostridia	E	amidohydrolase	-	-	-	ko:K01436	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
k141_5413_3	1304885.AUEY01000021_gene3462	2.05e-36	134.0	COG0427@1|root,COG0427@2|Bacteria,1MUGE@1224|Proteobacteria,42MHC@68525|delta/epsilon subdivisions,2WINZ@28221|Deltaproteobacteria,2MI87@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM Acetyl-CoA hydrolase transferase	-	-	-	-	-	-	-	-	-	-	-	iAF987.Gmet_3304	AcetylCoA_hyd_C,AcetylCoA_hydro,Acetyltransf_1
k141_5414_2	55601.VANGNB10_cI2286	5.47e-81	242.0	COG1762@1|root,COG1762@2|Bacteria,1RD0E@1224|Proteobacteria,1S668@1236|Gammaproteobacteria,1XWXU@135623|Vibrionales	135623|Vibrionales	G	Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)	ptsN	-	-	ko:K02806	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	-	-	-	PTS_EIIA_2
k141_5414_3	55601.VANGNB10_cI2285	1.1e-54	171.0	COG1544@1|root,COG1544@2|Bacteria,1MZHW@1224|Proteobacteria,1S8U1@1236|Gammaproteobacteria,1XXWR@135623|Vibrionales	135623|Vibrionales	J	COG1544 Ribosome-associated protein Y (PSrp-1)	yhbH	-	-	ko:K05808	-	-	-	-	ko00000,ko03009	-	-	-	Ribosomal_S30AE
k141_5414_4	945543.VIBR0546_01094	1.43e-280	775.0	COG1508@1|root,COG1508@2|Bacteria,1MW4V@1224|Proteobacteria,1RMY0@1236|Gammaproteobacteria,1XSDB@135623|Vibrionales	135623|Vibrionales	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	rpoN	-	-	ko:K03092	ko02020,ko05111,map02020,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma54_AID,Sigma54_CBD,Sigma54_DBD
k141_5414_5	1348635.BBJY01000009_gene1658	3.73e-153	432.0	COG1137@1|root,COG1137@2|Bacteria,1MU8M@1224|Proteobacteria,1RPW1@1236|Gammaproteobacteria,1XT67@135623|Vibrionales	135623|Vibrionales	S	abc transporter atp-binding protein	lptB	-	-	ko:K06861	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	1.B.42.1	-	-	ABC_tran,BCA_ABC_TP_C
k141_5414_6	1348635.BBJY01000009_gene1659	4.04e-74	226.0	COG1934@1|root,COG1934@2|Bacteria,1N776@1224|Proteobacteria,1RPM7@1236|Gammaproteobacteria,1XUJY@135623|Vibrionales	135623|Vibrionales	S	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm	lptA	-	-	ko:K09774	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	OstA
k141_5414_7	55601.VANGNB10_cI2281	1.16e-83	253.0	COG3117@1|root,COG3117@2|Bacteria,1RA1Y@1224|Proteobacteria,1SDZE@1236|Gammaproteobacteria,1XSM1@135623|Vibrionales	135623|Vibrionales	S	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA	lptC	-	-	ko:K11719	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	LptC
k141_5415_1	233412.HD_1144	2.13e-21	102.0	COG0815@1|root,COG0815@2|Bacteria,1MUBU@1224|Proteobacteria,1RM8M@1236|Gammaproteobacteria,1Y79W@135625|Pasteurellales	135625|Pasteurellales	M	Transfers the fatty acyl group on membrane lipoproteins	lnt	-	-	ko:K03820	-	-	-	-	ko00000,ko01000	-	GT2	-	CN_hydrolase
k141_5417_1	675815.VOA_001426	4.97e-23	91.3	2B22N@1|root,31UJJ@2|Bacteria,1QSF4@1224|Proteobacteria,1THZ8@1236|Gammaproteobacteria,1XXZ8@135623|Vibrionales	135623|Vibrionales	S	transcriptional regulators	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_5417_3	1219065.VPR01S_05_01960	2.11e-44	154.0	COG4175@1|root,COG4175@2|Bacteria,1MU86@1224|Proteobacteria,1RN2R@1236|Gammaproteobacteria,1XTVT@135623|Vibrionales	135623|Vibrionales	E	COG4175 ABC-type proline glycine betaine transport system, ATPase component	proV	-	3.6.3.32	ko:K02000	ko02010,map02010	M00208	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.12	-	-	ABC_tran,CBS
k141_3373_2	332101.JIBU02000050_gene3456	8.8e-246	685.0	COG3104@1|root,COG3104@2|Bacteria,1TP81@1239|Firmicutes,24BI4@186801|Clostridia,36FG1@31979|Clostridiaceae	186801|Clostridia	P	amino acid peptide transporter	-	-	-	-	-	-	-	-	-	-	-	-	PTR2
k141_3373_3	397288.C806_01370	8.91e-55	192.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,1TNZE@1239|Firmicutes,2480H@186801|Clostridia,27J5F@186928|unclassified Lachnospiraceae	186801|Clostridia	G	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	ACPS,Carb_kinase,YjeF_N
k141_2022_20	1511.CLOST_0010	2.86e-32	115.0	COG1366@1|root,COG1366@2|Bacteria,1VER8@1239|Firmicutes,24QWE@186801|Clostridia,25RX7@186804|Peptostreptococcaceae	186801|Clostridia	T	Belongs to the anti-sigma-factor antagonist family	rsbV	-	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS
k141_2022_21	1286171.EAL2_c00110	2.92e-52	170.0	COG2172@1|root,COG2172@2|Bacteria,1V1IA@1239|Firmicutes,24Q6W@186801|Clostridia,25ZQC@186806|Eubacteriaceae	186801|Clostridia	T	Histidine kinase-like ATPase domain	rsbW	-	2.7.11.1	ko:K04757	-	-	-	-	ko00000,ko01000,ko01001,ko03021	-	-	-	HATPase_c_2
k141_2022_22	1121324.CLIT_4c02310	3.47e-137	395.0	COG1191@1|root,COG1191@2|Bacteria,1TP3Q@1239|Firmicutes,2487Z@186801|Clostridia,25QQQ@186804|Peptostreptococcaceae	186801|Clostridia	K	Sigma-70 region 3	sigB	-	-	ko:K03090,ko:K03091	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r3,Sigma70_r4
k141_1571_1	870967.VIS19158_02485	1.52e-93	277.0	COG4384@1|root,COG4384@2|Bacteria,1PUM3@1224|Proteobacteria,1SHRM@1236|Gammaproteobacteria,1XYBM@135623|Vibrionales	135623|Vibrionales	S	Bacteriophage Mu Gp45 protein	-	-	-	-	-	-	-	-	-	-	-	-	Phage_Mu_Gp45
k141_1571_2	1187848.AJYQ01000156_gene3833	3.4e-143	413.0	COG4379@1|root,COG4379@2|Bacteria,1QJG0@1224|Proteobacteria,1THFJ@1236|Gammaproteobacteria,1XVF9@135623|Vibrionales	135623|Vibrionales	S	tail protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_1571_3	870967.VIS19158_02475	6.43e-163	470.0	COG4228@1|root,COG4228@2|Bacteria,1QJII@1224|Proteobacteria,1THIT@1236|Gammaproteobacteria,1XW67@135623|Vibrionales	135623|Vibrionales	S	DNA circularisation protein N-terminus	-	-	-	-	-	-	-	-	-	-	-	-	DNA_circ_N
k141_1571_4	675816.VIA_001502	1.75e-34	130.0	2DP21@1|root,3307B@2|Bacteria,1QTZG@1224|Proteobacteria,1T1PM@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	KilA-N	-	-	-	-	-	-	-	-	-	-	-	-	HTH_39,KilA-N
k141_941_32	1219065.VPR01S_02_01390	0.0	1304.0	COG1025@1|root,COG1025@2|Bacteria,1QTVC@1224|Proteobacteria,1T1IG@1236|Gammaproteobacteria,1XT1Q@135623|Vibrionales	135623|Vibrionales	O	Belongs to the peptidase M16 family	ptrA	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C,Peptidase_M16_M
k141_941_33	243277.VC_2073	2.56e-63	201.0	COG3102@1|root,COG3102@2|Bacteria,1RB98@1224|Proteobacteria,1SI78@1236|Gammaproteobacteria,1XUTF@135623|Vibrionales	135623|Vibrionales	S	protein conserved in bacteria	-	-	-	ko:K09907	-	-	-	-	ko00000	-	-	-	YecM
k141_1344_1	1392493.JIAB01000001_gene587	8.8e-10	60.1	COG0427@1|root,COG0427@2|Bacteria,1TPHC@1239|Firmicutes,247V0@186801|Clostridia,27K75@186928|unclassified Lachnospiraceae	186801|Clostridia	C	Acetyl-CoA hydrolase/transferase C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AcetylCoA_hyd_C,AcetylCoA_hydro
k141_5048_1	1304888.ATWF01000002_gene341	4.8e-49	162.0	COG1309@1|root,COG1309@2|Bacteria,2GGM9@200930|Deferribacteres	200930|Deferribacteres	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
k141_5048_2	1304888.ATWF01000002_gene340	4.86e-137	416.0	COG1033@1|root,COG1033@2|Bacteria,2GFIN@200930|Deferribacteres	200930|Deferribacteres	K	Sterol-sensing domain of SREBP cleavage-activation	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
k141_1346_1	945550.VISI1226_20864	6.54e-51	169.0	COG0037@1|root,COG0037@2|Bacteria,1MW5Q@1224|Proteobacteria,1RN2H@1236|Gammaproteobacteria,1XTQ4@135623|Vibrionales	135623|Vibrionales	J	Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system	ttcA	-	-	ko:K14058	-	-	-	-	ko00000,ko03016	-	-	-	ATP_bind_3
k141_1346_2	1219065.VPR01S_01_00520	1.3e-101	303.0	COG0589@1|root,COG0589@2|Bacteria,1MVZS@1224|Proteobacteria,1RPAE@1236|Gammaproteobacteria,1XSRX@135623|Vibrionales	135623|Vibrionales	T	COG0589 Universal stress protein UspA and related nucleotide-binding proteins	uspE	-	-	ko:K14055	-	-	-	-	ko00000	-	-	-	Usp
k141_944_1	485918.Cpin_3930	1.04e-34	144.0	COG3299@1|root,COG3299@2|Bacteria,4NF69@976|Bacteroidetes,1IX6R@117747|Sphingobacteriia	976|Bacteroidetes	S	homolog of phage Mu protein gp47	-	-	-	-	-	-	-	-	-	-	-	-	Baseplate_J
k141_1602_1	1304885.AUEY01000010_gene1657	3.23e-176	523.0	COG0178@1|root,COG0178@2|Bacteria,1MW0W@1224|Proteobacteria,42M4I@68525|delta/epsilon subdivisions,2WJHM@28221|Deltaproteobacteria,2MI09@213118|Desulfobacterales	28221|Deltaproteobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
k141_1602_2	1232437.KL662033_gene2669	5.06e-96	292.0	COG1995@1|root,COG1995@2|Bacteria,1MX5W@1224|Proteobacteria,42NJJ@68525|delta/epsilon subdivisions,2WJGI@28221|Deltaproteobacteria,2MHYF@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)	pdxA	-	1.1.1.262,1.1.1.408,1.1.1.409	ko:K00097,ko:K22024	ko00750,ko01100,map00750,map01100	M00124	R05681,R05837,R07406	RC00089,RC00675,RC01475	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxA
k141_1347_1	1307761.L21SP2_2649	2.02e-154	462.0	COG0610@1|root,COG0610@2|Bacteria,2J5UU@203691|Spirochaetes	203691|Spirochaetes	V	Subunit R is required for both nuclease and ATPase activities, but not for modification	hsdR	-	3.1.21.3	ko:K01153	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	DUF3387,EcoR124_C,HSDR_N,ResIII
k141_5049_1	1304885.AUEY01000004_gene962	9.49e-200	561.0	COG3825@1|root,COG3825@2|Bacteria,1MUAJ@1224|Proteobacteria,42N7R@68525|delta/epsilon subdivisions,2WJBI@28221|Deltaproteobacteria,2MIB1@213118|Desulfobacterales	28221|Deltaproteobacteria	S	VWA containing CoxE family protein	-	-	-	ko:K09989	-	-	-	-	ko00000	-	-	-	VWA_CoxE
k141_5049_2	1265505.ATUG01000001_gene4288	2.86e-167	475.0	COG0473@1|root,COG0473@2|Bacteria,1MUH4@1224|Proteobacteria,42M8G@68525|delta/epsilon subdivisions,2WIYB@28221|Deltaproteobacteria,2MIG1@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate	leuB	GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
k141_5050_1	1280685.AUKC01000012_gene1517	6.59e-56	181.0	COG2452@1|root,COG2452@2|Bacteria,1UZ1U@1239|Firmicutes,24F52@186801|Clostridia,4BYPI@830|Butyrivibrio	186801|Clostridia	L	Resolvase, N terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MerR,MerR_1,Resolvase
k141_1603_1	870967.VIS19158_09992	9.86e-99	294.0	COG2801@1|root,COG2801@2|Bacteria,1PBHA@1224|Proteobacteria,1RQ7I@1236|Gammaproteobacteria,1XSS2@135623|Vibrionales	135623|Vibrionales	L	Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_32,rve,rve_3
k141_1603_2	1280694.AUJQ01000004_gene564	1.4e-22	93.2	COG3415@1|root,COG3415@2|Bacteria,1UM7U@1239|Firmicutes,25GB9@186801|Clostridia	186801|Clostridia	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_2630_1	672.VV93_v1c12070	2.28e-263	731.0	COG0469@1|root,COG0469@2|Bacteria,1MU21@1224|Proteobacteria,1RMW3@1236|Gammaproteobacteria,1XSQD@135623|Vibrionales	135623|Vibrionales	G	Belongs to the pyruvate kinase family	pykA	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PK,PK_C
k141_2630_2	945543.VIBR0546_04302	4.57e-175	501.0	COG1940@1|root,COG1940@2|Bacteria,1MX6M@1224|Proteobacteria,1RNZ1@1236|Gammaproteobacteria,1XTAB@135623|Vibrionales	135623|Vibrionales	GK	COG1940 Transcriptional regulator sugar kinase	mlc	-	-	ko:K15545	-	-	-	-	ko00000,ko03000	-	-	-	ROK
k141_2630_3	675815.VOA_002352	9.33e-179	503.0	COG0784@1|root,COG0835@1|root,COG0784@2|Bacteria,COG0835@2|Bacteria,1N81M@1224|Proteobacteria,1RPS1@1236|Gammaproteobacteria,1XT9E@135623|Vibrionales	135623|Vibrionales	T	COG0835 Chemotaxis signal transduction protein	-	-	-	ko:K03415	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	CheW,Response_reg
k141_2630_4	1517681.HW45_23450	0.0	1483.0	COG0587@1|root,COG0587@2|Bacteria,1MUE4@1224|Proteobacteria,1RQA8@1236|Gammaproteobacteria,1XVW2@135623|Vibrionales	135623|Vibrionales	L	DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase	dnaE2	-	2.7.7.7	ko:K14162	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
k141_2630_5	1348635.BBJY01000007_gene86	7.15e-170	493.0	COG0389@1|root,COG0389@2|Bacteria,1MU5X@1224|Proteobacteria,1S28B@1236|Gammaproteobacteria,1XU19@135623|Vibrionales	135623|Vibrionales	L	Nucleotidyltransferase DNA polymerase involved in DNA repair	-	-	-	ko:K14161	-	-	-	-	ko00000,ko03400	-	-	-	IMS
k141_2630_6	945550.VISI1226_21454	1.47e-73	229.0	COG4544@1|root,COG4544@2|Bacteria,1MZQU@1224|Proteobacteria,1S9RP@1236|Gammaproteobacteria,1XV15@135623|Vibrionales	135623|Vibrionales	S	COG0468 RecA RadA recombinase	-	-	-	-	-	-	-	-	-	-	-	-	RecA
k141_5051_1	879212.DespoDRAFT_02733	6.65e-18	84.7	COG2027@1|root,COG2027@2|Bacteria,1MW40@1224|Proteobacteria,42R96@68525|delta/epsilon subdivisions,2WMVV@28221|Deltaproteobacteria,2MHT9@213118|Desulfobacterales	28221|Deltaproteobacteria	M	PFAM peptidase S13 D-Ala-D-Ala carboxypeptidase C	dacB	-	3.4.16.4	ko:K07259	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S13
k141_5051_2	1304885.AUEY01000068_gene1405	1.28e-49	162.0	COG1490@1|root,COG1490@2|Bacteria,1RGTV@1224|Proteobacteria,42SMU@68525|delta/epsilon subdivisions,2WP4P@28221|Deltaproteobacteria,2MK67@213118|Desulfobacterales	28221|Deltaproteobacteria	J	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality	dtd	GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360	-	ko:K07560	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Tyr_Deacylase
k141_4031_2	293826.Amet_3591	5.36e-31	119.0	COG1978@1|root,COG1978@2|Bacteria,1TPAB@1239|Firmicutes,2487X@186801|Clostridia,36DEZ@31979|Clostridiaceae	186801|Clostridia	S	glycine betaine sarcosine D-proline reductase family	-	-	1.21.4.2	ko:K10672	-	-	-	-	ko00000,ko01000	-	-	-	GRDB
k141_4031_3	562983.HMPREF0433_00601	3.79e-167	476.0	COG1978@1|root,COG1978@2|Bacteria,1TPAB@1239|Firmicutes,4HDWJ@91061|Bacilli,3WEP2@539002|Bacillales incertae sedis	91061|Bacilli	S	Glycine/sarcosine/betaine reductase selenoprotein B (GRDB)	-	-	-	-	-	-	-	-	-	-	-	-	GRDB
k141_4031_4	1121289.JHVL01000018_gene609	4.11e-52	166.0	2AE14@1|root,313TT@2|Bacteria,1V6GX@1239|Firmicutes,24K4C@186801|Clostridia,36JTG@31979|Clostridiaceae	186801|Clostridia	C	In the first step of glycine, betaine and sarcosine reductases, the substrate is bound to component PB via a Schiff base intermediate. Then the PB-activated substrate is nucleophilically attacked by the selenol anion of component PA to transform it to a carboxymethylated selenoether and the respective amine. By action of component PC, acetyl phosphate is formed, leaving component PA in its oxidized state. Finally component PA becomes reduced by the thioredoxin system to start a new catalytic cycle of reductive deamination	grdA	-	1.21.4.2,1.21.4.3,1.21.4.4	ko:K10670	-	-	-	-	ko00000,ko01000	-	-	-	GRDA
k141_4031_5	293826.Amet_3592	4.25e-16	73.6	2AE14@1|root,313TT@2|Bacteria,1V6GX@1239|Firmicutes,24K4C@186801|Clostridia,36JTG@31979|Clostridiaceae	186801|Clostridia	C	In the first step of glycine, betaine and sarcosine reductases, the substrate is bound to component PB via a Schiff base intermediate. Then the PB-activated substrate is nucleophilically attacked by the selenol anion of component PA to transform it to a carboxymethylated selenoether and the respective amine. By action of component PC, acetyl phosphate is formed, leaving component PA in its oxidized state. Finally component PA becomes reduced by the thioredoxin system to start a new catalytic cycle of reductive deamination	grdA	-	1.21.4.2,1.21.4.3,1.21.4.4	ko:K10670	-	-	-	-	ko00000,ko01000	-	-	-	GRDA
k141_4031_6	1121324.CLIT_20c00930	1.86e-242	674.0	28HF7@1|root,2Z7RC@2|Bacteria,1TQET@1239|Firmicutes,249YW@186801|Clostridia,25QXA@186804|Peptostreptococcaceae	186801|Clostridia	C	Glycine/sarcosine/betaine reductase component B subunits	grdE	-	1.21.4.2	ko:K10671	-	-	-	-	ko00000,ko01000	-	-	-	Gly_reductase
k141_4031_7	1151292.QEW_2891	3.86e-46	150.0	COG3118@1|root,COG3118@2|Bacteria,1UHX3@1239|Firmicutes,24JPM@186801|Clostridia,25RVE@186804|Peptostreptococcaceae	186801|Clostridia	O	Belongs to the thioredoxin family	trxA	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
k141_4031_8	1123009.AUID01000013_gene1733	3.07e-152	436.0	COG0492@1|root,COG0492@2|Bacteria,1TNZS@1239|Firmicutes,2491M@186801|Clostridia,26861@186813|unclassified Clostridiales	186801|Clostridia	C	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family	trxB	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
k141_4031_9	411468.CLOSCI_00776	1.47e-17	79.7	2E36T@1|root,32Y6H@2|Bacteria,1VEXQ@1239|Firmicutes,24RAE@186801|Clostridia,22420@1506553|Lachnoclostridium	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_4031_10	1286171.EAL2_c08720	4.2e-75	237.0	COG1307@1|root,COG1307@2|Bacteria,1TQDI@1239|Firmicutes,24ADT@186801|Clostridia,25W2S@186806|Eubacteriaceae	186801|Clostridia	S	EDD domain protein, DegV family	-	-	-	-	-	-	-	-	-	-	-	-	DegV
k141_4031_11	1511.CLOST_1106	1.63e-101	305.0	COG1307@1|root,COG1307@2|Bacteria,1TRM7@1239|Firmicutes,247ST@186801|Clostridia	186801|Clostridia	T	EDD domain protein, DegV family	-	-	-	-	-	-	-	-	-	-	-	-	DegV
k141_4031_12	536232.CLM_0267	2.02e-53	173.0	COG0219@1|root,COG0219@2|Bacteria,1V3GW@1239|Firmicutes,24HVV@186801|Clostridia,36I1E@31979|Clostridiaceae	186801|Clostridia	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily	trmL	-	2.1.1.207	ko:K03216	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
k141_4031_13	1304284.L21TH_2409	7.97e-88	277.0	COG1143@1|root,COG2006@1|root,COG1143@2|Bacteria,COG2006@2|Bacteria,1TRX2@1239|Firmicutes,249GX@186801|Clostridia,36GCZ@31979|Clostridiaceae	186801|Clostridia	C	Domain of unknown function (DUF362)	-	-	-	-	-	-	-	-	-	-	-	-	DUF362,Fer4,Fer4_10,Fer4_7
k141_4031_14	1033737.CAEV01000048_gene1319	1.33e-50	175.0	COG0561@1|root,COG0561@2|Bacteria,1TREF@1239|Firmicutes,25AZZ@186801|Clostridia,36WB6@31979|Clostridiaceae	186801|Clostridia	S	hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
k141_4031_15	1408473.JHXO01000009_gene3311	7.35e-05	50.1	COG0406@1|root,COG0406@2|Bacteria,4NPZ0@976|Bacteroidetes,2FPTF@200643|Bacteroidia	976|Bacteroidetes	G	Belongs to the phosphoglycerate mutase family	-	-	5.4.2.12	ko:K15634,ko:K15640	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	His_Phos_1
k141_4031_16	1511.CLOST_1102	4.05e-65	210.0	COG0368@1|root,COG0368@2|Bacteria,1V1QB@1239|Firmicutes,24I0D@186801|Clostridia,25QDZ@186804|Peptostreptococcaceae	186801|Clostridia	H	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate	cobS	-	2.7.8.26	ko:K02233	ko00860,ko01100,map00860,map01100	M00122	R05223,R11174	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CobS
k141_4031_17	1151292.QEW_4060	2.01e-70	218.0	COG2087@1|root,COG2087@2|Bacteria,1V6F8@1239|Firmicutes,24JF6@186801|Clostridia,25RRM@186804|Peptostreptococcaceae	186801|Clostridia	H	Cobinamide kinase / cobinamide phosphate guanyltransferase	cobU	-	2.7.1.156,2.7.7.62	ko:K02231	ko00860,ko01100,map00860,map01100	M00122	R05221,R05222,R06558	RC00002,RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	CobU
k141_4031_18	1121324.CLIT_10c02760	1.31e-75	236.0	COG1655@1|root,COG1655@2|Bacteria,1UY0V@1239|Firmicutes,247VR@186801|Clostridia	186801|Clostridia	K	protein conserved in bacteria	-	-	-	ko:K09766	-	-	-	-	ko00000	-	-	-	DUF2225,cNMP_binding
k141_4031_19	1151292.QEW_1840	8.94e-75	249.0	COG2720@1|root,COG2720@2|Bacteria,1TSH8@1239|Firmicutes,2493X@186801|Clostridia,25QWE@186804|Peptostreptococcaceae	186801|Clostridia	V	G5	-	-	-	ko:K18346	ko01502,ko02020,map01502,map02020	M00651	-	-	ko00000,ko00001,ko00002,ko01504	-	-	-	G5,PG_binding_4,VanW
k141_4031_20	1499684.CCNP01000023_gene3394	3.89e-78	240.0	COG0177@1|root,COG0177@2|Bacteria,1TRAK@1239|Firmicutes,24899@186801|Clostridia,36DBQ@31979|Clostridiaceae	186801|Clostridia	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD
k141_4031_21	500633.CLOHIR_01796	6.85e-89	275.0	COG1600@1|root,COG1600@2|Bacteria,1TP6Q@1239|Firmicutes,248M5@186801|Clostridia,25R2C@186804|Peptostreptococcaceae	186801|Clostridia	C	Domain of unknown function (DUF1730)	queG	-	1.17.99.6	ko:K18979	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF1730,Fer4_16,HEAT_2
k141_4031_22	572544.Ilyop_0561	1.47e-223	630.0	COG1115@1|root,COG1115@2|Bacteria,3795Z@32066|Fusobacteria	32066|Fusobacteria	E	Psort location CytoplasmicMembrane, score 10.00	-	-	-	ko:K03310	-	-	-	-	ko00000	2.A.25	-	-	Na_Ala_symp
k141_4031_23	1229783.C273_09367	1.48e-35	133.0	COG3279@1|root,COG3279@2|Bacteria,1V392@1239|Firmicutes,4HHAI@91061|Bacilli,4GY5G@90964|Staphylococcaceae	91061|Bacilli	K	Regulator	agrA	-	-	ko:K07707	ko02020,ko02024,map02020,map02024	M00495	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	LytTR,Response_reg
k141_4031_24	1385510.N781_17160	4.93e-128	392.0	COG3227@1|root,COG3227@2|Bacteria,1TP08@1239|Firmicutes,4H9S6@91061|Bacilli,2Y9Y7@289201|Pontibacillus	91061|Bacilli	E	Peptidase M4	-	-	3.4.24.28	ko:K01400	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	FTP,PPC,PepSY,Peptidase_M4,Peptidase_M4_C
k141_4031_25	441769.ABFU01000010_gene2611	4.28e-108	340.0	COG3227@1|root,COG3227@2|Bacteria,1TP08@1239|Firmicutes,4H9S6@91061|Bacilli,1ZCEP@1386|Bacillus	91061|Bacilli	E	Peptidase M4	nprE	GO:0005575,GO:0005576	3.4.24.28	ko:K01400	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	FTP,PPC,PepSY,Peptidase_M4,Peptidase_M4_C
k141_4031_26	226185.EF_2470	3.62e-36	130.0	COG1078@1|root,COG1078@2|Bacteria,1UHY1@1239|Firmicutes,4ISAF@91061|Bacilli,4B0RZ@81852|Enterococcaceae	91061|Bacilli	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	ko:K06950	-	-	-	-	ko00000	-	-	-	HD
k141_4031_27	1286171.EAL2_c04210	5.54e-228	640.0	COG0502@1|root,COG0502@2|Bacteria,1TPEX@1239|Firmicutes,248PF@186801|Clostridia,25V8I@186806|Eubacteriaceae	186801|Clostridia	C	Biotin and Thiamin Synthesis associated domain	hydG	-	4.1.99.19	ko:K03150	ko00730,ko01100,map00730,map01100	-	R10246	RC01434,RC03095	ko00000,ko00001,ko01000	-	-	-	BATS,Radical_SAM
k141_4031_28	545243.BAEV01000006_gene1309	4.99e-30	108.0	COG0864@1|root,COG0864@2|Bacteria,1VF9M@1239|Firmicutes,24QVJ@186801|Clostridia,36N04@31979|Clostridiaceae	186801|Clostridia	K	Iron-only hydrogenase system regulator	-	-	-	-	-	-	-	-	-	-	-	-	NikR_C
k141_4031_29	1499689.CCNN01000009_gene2866	1.39e-152	441.0	COG0502@1|root,COG0502@2|Bacteria,1TPYQ@1239|Firmicutes,248H8@186801|Clostridia,36DIQ@31979|Clostridiaceae	186801|Clostridia	C	radical SAM domain protein	hydE	-	2.8.1.6	ko:K01012	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R01078	RC00441	ko00000,ko00001,ko00002,ko01000	-	-	-	BATS,Radical_SAM
k141_4031_30	1121324.CLIT_23c00780	2.12e-247	690.0	COG1966@1|root,COG1966@2|Bacteria,1TQN8@1239|Firmicutes,248DZ@186801|Clostridia,25QTF@186804|Peptostreptococcaceae	186801|Clostridia	T	Carbon starvation protein CstA	cstA	-	-	-	-	-	-	-	-	-	-	-	CstA,CstA_5TM
k141_4031_31	318464.IO99_04295	3.87e-86	263.0	COG3279@1|root,COG3279@2|Bacteria,1V14X@1239|Firmicutes,24BG9@186801|Clostridia,36E97@31979|Clostridiaceae	186801|Clostridia	KT	response regulator	ypdB	-	-	ko:K02477,ko:K07705	ko02020,map02020	M00492	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	LytTR,Response_reg
k141_4031_32	1443122.Z958_03090	1.72e-194	562.0	COG3275@1|root,COG3275@2|Bacteria,1VTXF@1239|Firmicutes,25E5Z@186801|Clostridia,36E2G@31979|Clostridiaceae	186801|Clostridia	T	Histidine kinase	ypdA	-	2.7.13.3	ko:K02478,ko:K07704	ko02020,map02020	M00492	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	5TM-5TMR_LYT,GAF_3,HATPase_c,His_kinase
k141_4031_33	272563.CD630_25610	6.6e-206	590.0	COG1461@1|root,COG1461@2|Bacteria,1TQMX@1239|Firmicutes,247XI@186801|Clostridia,25QKG@186804|Peptostreptococcaceae	186801|Clostridia	S	DAK2 domain fusion protein YloV	yloV	-	-	ko:K07030	-	-	-	-	ko00000	-	-	-	Dak1_2,Dak2
k141_4031_34	445971.ANASTE_02003	1.56e-30	112.0	COG1302@1|root,COG1302@2|Bacteria,1V731@1239|Firmicutes,24JIA@186801|Clostridia,25WQ4@186806|Eubacteriaceae	186801|Clostridia	S	Asp23 family, cell envelope-related function	-	-	-	-	-	-	-	-	-	-	-	-	Asp23
k141_4031_35	1262915.BN574_01019	3.96e-27	99.8	COG0227@1|root,COG0227@2|Bacteria,1VEI2@1239|Firmicutes	1239|Firmicutes	J	Belongs to the bacterial ribosomal protein bL28 family	rpmB	-	-	ko:K02902	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L28
k141_4031_37	1151292.QEW_0523	1e-154	448.0	COG0500@1|root,COG0500@2|Bacteria,1UHX5@1239|Firmicutes,25E63@186801|Clostridia,25UPV@186804|Peptostreptococcaceae	186801|Clostridia	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_32
k141_4031_38	445970.ALIPUT_02060	2.52e-06	53.5	COG1787@1|root,COG1787@2|Bacteria,4NNG6@976|Bacteroidetes,2FSFZ@200643|Bacteroidia	976|Bacteroidetes	L	Restriction endonuclease	-	-	-	ko:K07448	-	-	-	-	ko00000,ko02048	-	-	-	Mrr_cat
k141_4031_39	1345695.CLSA_c19650	1.87e-74	259.0	COG0840@1|root,COG0840@2|Bacteria,1TP5A@1239|Firmicutes,247S3@186801|Clostridia,36EQK@31979|Clostridiaceae	186801|Clostridia	NT	chemotaxis	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal,dCache_1
k141_4031_40	1292035.H476_0342	1.71e-111	326.0	COG1768@1|root,COG1768@2|Bacteria,1V3XB@1239|Firmicutes,249BN@186801|Clostridia,25R0P@186804|Peptostreptococcaceae	186801|Clostridia	S	Ser Thr phosphatase family protein	-	-	-	ko:K07099	-	-	-	-	ko00000	-	-	-	Metallophos
k141_4031_41	1216362.B437_04165	5.96e-33	127.0	COG0037@1|root,COG0037@2|Bacteria,378FH@32066|Fusobacteria	32066|Fusobacteria	H	Belongs to the TtcA family	-	-	-	-	-	-	-	-	-	-	-	-	ATP_bind_3
k141_4031_42	1121324.CLIT_10c03940	1.64e-129	374.0	COG2357@1|root,COG2357@2|Bacteria,1TQ2F@1239|Firmicutes,249FE@186801|Clostridia,25QGC@186804|Peptostreptococcaceae	186801|Clostridia	S	RelA SpoT domain protein	yjbM	-	2.7.6.5	ko:K07816	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	RelA_SpoT
k141_4031_43	1121324.CLIT_10c03950	4.05e-104	313.0	COG0491@1|root,COG0491@2|Bacteria,1TT3D@1239|Firmicutes,24BV1@186801|Clostridia,25QQM@186804|Peptostreptococcaceae	186801|Clostridia	S	Metallo-beta-lactamase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
k141_4031_44	500633.CLOHIR_01853	0.0	1111.0	COG1882@1|root,COG1882@2|Bacteria,1TPTF@1239|Firmicutes,247YY@186801|Clostridia,25R2X@186804|Peptostreptococcaceae	186801|Clostridia	C	Psort location Cytoplasmic, score	pflB	-	2.3.1.54	ko:K00656	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	-	R00212,R06987	RC00004,RC01181,RC02742,RC02833	ko00000,ko00001,ko01000	-	-	-	Gly_radical,PFL-like
k141_4031_45	696747.NIES39_A04120	1.51e-104	310.0	COG1180@1|root,COG1180@2|Bacteria,1G268@1117|Cyanobacteria,1H7HG@1150|Oscillatoriales	1117|Cyanobacteria	C	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine	pflA	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
k141_4031_46	509191.AEDB02000108_gene1673	1.08e-40	145.0	COG1564@1|root,COG1564@2|Bacteria,1VA0W@1239|Firmicutes,24NG6@186801|Clostridia,3WJUT@541000|Ruminococcaceae	186801|Clostridia	H	thiamine pyrophosphokinase	thiN	-	2.7.6.2	ko:K00949	ko00730,ko01100,map00730,map01100	-	R00619	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	TPK_B1_binding,TPK_catalytic
k141_4031_47	1292035.H476_2037	1.23e-114	333.0	COG0036@1|root,COG0036@2|Bacteria,1TQK8@1239|Firmicutes,248AR@186801|Clostridia,25R34@186804|Peptostreptococcaceae	186801|Clostridia	G	Belongs to the ribulose-phosphate 3-epimerase family	rpe	-	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
k141_4031_48	1121324.CLIT_23c03080	1.22e-127	372.0	COG1162@1|root,COG1162@2|Bacteria,1TPSQ@1239|Firmicutes,248R5@186801|Clostridia,25QPZ@186804|Peptostreptococcaceae	186801|Clostridia	S	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit	rsgA	-	3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100	-	R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009	-	-	-	RsgA_GTPase,RsgA_N
k141_4031_49	1511.CLOST_1849	1.27e-136	422.0	COG0515@1|root,COG0515@2|Bacteria,1TP3F@1239|Firmicutes,2492G@186801|Clostridia,25QJS@186804|Peptostreptococcaceae	186801|Clostridia	KLT	Psort location CytoplasmicMembrane, score	prkC	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
k141_4031_50	858215.Thexy_1387	5.52e-47	163.0	COG0631@1|root,COG0631@2|Bacteria,1V6K5@1239|Firmicutes,24JD4@186801|Clostridia,42EM8@68295|Thermoanaerobacterales	186801|Clostridia	T	protein phosphatase 2C domain protein	stp	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C,PP2C_2
k141_4031_51	1286171.EAL2_c14690	8.69e-146	422.0	COG0820@1|root,COG0820@2|Bacteria,1TPVF@1239|Firmicutes,248BC@186801|Clostridia,25UW3@186806|Eubacteriaceae	186801|Clostridia	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	-	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Fer4_14,Radical_SAM
k141_4031_52	1151292.QEW_3126	6.22e-165	478.0	COG0144@1|root,COG0781@1|root,COG0144@2|Bacteria,COG0781@2|Bacteria,1TP3N@1239|Firmicutes,248CS@186801|Clostridia,25QCI@186804|Peptostreptococcaceae	186801|Clostridia	J	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA	sun	-	2.1.1.176	ko:K03500	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F,Methyltr_RsmF_N,NusB
k141_4031_53	1304284.L21TH_0669	9.59e-61	197.0	COG1852@1|root,COG1852@2|Bacteria,1V1B5@1239|Firmicutes,24G2F@186801|Clostridia,36K8X@31979|Clostridiaceae	186801|Clostridia	S	Protein of unknown function DUF116	-	-	-	ko:K09729	-	-	-	-	ko00000	-	-	-	DUF116
k141_1605_2	1295642.H839_13669	6.19e-19	84.0	COG0424@1|root,COG0424@2|Bacteria,1V6FH@1239|Firmicutes,4HIMK@91061|Bacilli,1WFYG@129337|Geobacillus	91061|Bacilli	D	Involved in septum formation	maf	GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0005575,GO:0005623,GO:0007049,GO:0008150,GO:0009987,GO:0016043,GO:0022402,GO:0022607,GO:0030428,GO:0032506,GO:0044085,GO:0044464,GO:0051301,GO:0061640,GO:0071840,GO:0090529,GO:1902410,GO:1903047	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
k141_5053_1	674977.VMC_20930	7.56e-98	292.0	COG1496@1|root,COG1496@2|Bacteria,1MW2H@1224|Proteobacteria,1RNV4@1236|Gammaproteobacteria,1XSY8@135623|Vibrionales	135623|Vibrionales	S	Belongs to the multicopper oxidase YfiH RL5 family	yfiH	-	-	ko:K05810	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase_4
k141_4032_1	945543.VIBR0546_11727	2.92e-58	182.0	COG0662@1|root,COG0662@2|Bacteria,1QU6E@1224|Proteobacteria,1T256@1236|Gammaproteobacteria,1XWZZ@135623|Vibrionales	135623|Vibrionales	G	Catalyzes the circularization of gamma-N-acetyl- alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6- tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant	ectC	-	4.2.1.108	ko:K06720	ko00260,ko01100,ko01120,map00260,map01100,map01120	M00033	R06979	RC01729	ko00000,ko00001,ko00002,ko01000	-	-	-	Ectoine_synth
k141_4032_2	575788.VS_II0069	6.26e-31	119.0	COG0527@1|root,COG0527@2|Bacteria,1MVSI@1224|Proteobacteria,1RQ37@1236|Gammaproteobacteria,1XUVY@135623|Vibrionales	135623|Vibrionales	E	Amino acid kinase family	-	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
k141_2631_2	696369.KI912183_gene2554	1.12e-30	114.0	COG3339@1|root,COG3339@2|Bacteria,1VAM6@1239|Firmicutes,24KQN@186801|Clostridia,2637V@186807|Peptococcaceae	186801|Clostridia	S	Protein of unknown function (DUF1232)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1232
k141_1349_1	391615.ABSJ01000050_gene1149	7.99e-09	67.4	COG4222@1|root,COG4222@2|Bacteria,1QVYZ@1224|Proteobacteria,1T2ND@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_4034_1	675815.VOA_002123	2.14e-92	277.0	COG2227@1|root,COG2227@2|Bacteria,1MY0S@1224|Proteobacteria,1RP69@1236|Gammaproteobacteria,1XSUE@135623|Vibrionales	135623|Vibrionales	J	Catalyzes the methylation of 5-carboxymethoxyuridine (cmo5U) to form 5-methoxycarbonylmethoxyuridine (mcmo5U) at position 34 in tRNAs	cmoM	-	-	ko:K06219	-	-	-	-	ko00000	-	-	-	Methyltransf_11,Methyltransf_31
k141_4036_1	1129794.C427_1151	2.91e-48	175.0	COG2199@1|root,COG2200@1|root,COG3279@1|root,COG2199@2|Bacteria,COG2200@2|Bacteria,COG3279@2|Bacteria,1QWZS@1224|Proteobacteria,1T31E@1236|Gammaproteobacteria,46D2T@72275|Alteromonadaceae	1236|Gammaproteobacteria	T	Domain of unknown function (DUF3369)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3369,EAL,GGDEF
k141_750_4	1236541.BALL01000028_gene3150	5.36e-57	210.0	COG2849@1|root,COG2849@2|Bacteria,1MZAB@1224|Proteobacteria,1T18P@1236|Gammaproteobacteria,2QESG@267890|Shewanellaceae	1236|Gammaproteobacteria	S	MORN repeat variant	-	-	-	-	-	-	-	-	-	-	-	-	MORN_2
k141_750_5	1348635.BBJY01000008_gene1737	1.04e-183	518.0	COG1087@1|root,COG1087@2|Bacteria,1MUHI@1224|Proteobacteria,1RMTU@1236|Gammaproteobacteria,1XSCZ@135623|Vibrionales	135623|Vibrionales	M	udp-glucose 4-epimerase	galE	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
k141_750_6	945543.VIBR0546_18171	2.81e-221	613.0	COG1085@1|root,COG1085@2|Bacteria,1MU3E@1224|Proteobacteria,1RMDK@1236|Gammaproteobacteria,1XTKC@135623|Vibrionales	135623|Vibrionales	H	Galactose-1-phosphate uridylyltransferase	galT	-	2.7.7.12	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	M00362,M00554,M00632	R00955	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	GalP_UDP_tr_C,GalP_UDP_transf
k141_750_7	1248232.BANQ01000155_gene4220	9.37e-198	557.0	COG0153@1|root,COG0153@2|Bacteria,1MVQD@1224|Proteobacteria,1RQ0C@1236|Gammaproteobacteria,1XUF3@135623|Vibrionales	135623|Vibrionales	F	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)	galK	GO:0003674,GO:0003824,GO:0004335,GO:0005975,GO:0005996,GO:0006012,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019200,GO:0019318,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0046835,GO:0071704	2.7.1.6	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00554,M00632	R01092	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	GHMP_kinases_C,GHMP_kinases_N,GalKase_gal_bdg
k141_750_8	945543.VIBR0546_18201	6.11e-161	459.0	COG1609@1|root,COG1609@2|Bacteria,1MU1G@1224|Proteobacteria,1RMSP@1236|Gammaproteobacteria,1XTZQ@135623|Vibrionales	135623|Vibrionales	K	transcriptional regulators	galR	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
k141_750_9	675812.VHA_002559	0.0	892.0	COG4146@1|root,COG4146@2|Bacteria,1MXWV@1224|Proteobacteria,1RR4S@1236|Gammaproteobacteria,1XW1R@135623|Vibrionales	135623|Vibrionales	S	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	yidK	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
k141_750_10	1116375.VEJY3_08195	9.72e-19	80.1	2EGFD@1|root,33A7D@2|Bacteria,1NH03@1224|Proteobacteria,1SGGZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF1656)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1656
k141_750_11	1116375.VEJY3_08190	8e-129	374.0	COG1566@1|root,COG1566@2|Bacteria,1MWG0@1224|Proteobacteria,1RRE3@1236|Gammaproteobacteria,1XXAX@135623|Vibrionales	135623|Vibrionales	V	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
k141_750_12	1515746.HR45_12970	2.92e-228	658.0	COG1289@1|root,COG1289@2|Bacteria,1MX9H@1224|Proteobacteria,1RMJ4@1236|Gammaproteobacteria,2QD4G@267890|Shewanellaceae	1236|Gammaproteobacteria	S	Fusaric acid resistance protein family	-	-	-	-	-	-	-	-	-	-	-	-	FUSC
k141_750_13	672.VV93_v1c18630	2.45e-231	643.0	COG1448@1|root,COG1448@2|Bacteria,1MUT0@1224|Proteobacteria,1RN02@1236|Gammaproteobacteria,1XTX4@135623|Vibrionales	135623|Vibrionales	E	COG1448 Aspartate tyrosine aromatic aminotransferase	aspC	-	2.6.1.57	ko:K00832	ko00270,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230	M00024,M00025,M00034,M00040	R00694,R00734,R01731,R07396,R10845	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
k141_750_14	1191299.AJYX01000096_gene1993	1.4e-313	857.0	COG0017@1|root,COG0017@2|Bacteria,1MWFV@1224|Proteobacteria,1RMU4@1236|Gammaproteobacteria,1XSJD@135623|Vibrionales	135623|Vibrionales	J	COG0017 Aspartyl asparaginyl-tRNA synthetases	asnS	GO:0003674,GO:0003824,GO:0004812,GO:0004816,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006421,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.22	ko:K01893	ko00970,map00970	M00359,M00360	R03648	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
k141_750_15	675815.VOA_000290	3.87e-137	390.0	COG1136@1|root,COG1136@2|Bacteria,1NCFC@1224|Proteobacteria,1S18G@1236|Gammaproteobacteria,1XTFP@135623|Vibrionales	135623|Vibrionales	V	ABC-type antimicrobial peptide transport system, ATPase component	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
k141_750_16	55601.VANGNB10_cI1163	6.3e-268	769.0	COG0577@1|root,COG0577@2|Bacteria,1MVCT@1224|Proteobacteria,1RNP1@1236|Gammaproteobacteria,1XUDJ@135623|Vibrionales	135623|Vibrionales	V	ABC-type antimicrobial peptide transport system, permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
k141_750_17	223926.28806216	1.69e-185	526.0	COG3004@1|root,COG3004@2|Bacteria,1MW15@1224|Proteobacteria,1RNDE@1236|Gammaproteobacteria,1XT58@135623|Vibrionales	135623|Vibrionales	P	) H( ) antiporter that extrudes sodium in exchange for external protons	nhaA	GO:0003674,GO:0005215,GO:0005451,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008150,GO:0008324,GO:0015075,GO:0015077,GO:0015078,GO:0015081,GO:0015291,GO:0015297,GO:0015298,GO:0015299,GO:0015318,GO:0015385,GO:0015491,GO:0015672,GO:0022804,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0035725,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0098655,GO:0098660,GO:0098662,GO:0099516,GO:1902600	-	ko:K03313	-	-	-	-	ko00000,ko02000	2.A.33.1	-	-	Na_H_antiport_1
k141_3802_1	1121396.KB892924_gene641	2.1e-40	148.0	COG1619@1|root,COG1619@2|Bacteria,1MWIY@1224|Proteobacteria,42Q52@68525|delta/epsilon subdivisions,2WJ3S@28221|Deltaproteobacteria,2MICC@213118|Desulfobacterales	28221|Deltaproteobacteria	V	PFAM peptidase U61 LD-carboxypeptidase A	-	-	3.4.17.13	ko:K01297	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_S66
k141_3802_2	1121405.dsmv_0470	2.34e-69	228.0	COG1680@1|root,COG1680@2|Bacteria,1QUYZ@1224|Proteobacteria,42PUC@68525|delta/epsilon subdivisions,2WK0V@28221|Deltaproteobacteria,2MIWD@213118|Desulfobacterales	28221|Deltaproteobacteria	V	PFAM Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
k141_3802_3	1121396.KB892924_gene643	4.18e-195	546.0	COG1077@1|root,COG1077@2|Bacteria,1MUMW@1224|Proteobacteria,42M1J@68525|delta/epsilon subdivisions,2WIQR@28221|Deltaproteobacteria,2MIWY@213118|Desulfobacterales	28221|Deltaproteobacteria	D	TIGRFAM cell shape determining protein, MreB Mrl family	mreB	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
k141_751_1	742741.HMPREF9475_02366	2.27e-14	68.9	COG0662@1|root,COG0662@2|Bacteria,1V7HI@1239|Firmicutes,24JQZ@186801|Clostridia,2230U@1506553|Lachnoclostridium	186801|Clostridia	G	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
k141_4831_1	1348635.BBJY01000003_gene3724	1.33e-118	353.0	COG0626@1|root,COG0626@2|Bacteria,1MU57@1224|Proteobacteria,1RMCV@1236|Gammaproteobacteria,1Y0JI@135623|Vibrionales	135623|Vibrionales	E	Cys/Met metabolism PLP-dependent enzyme	-	-	4.4.1.11	ko:K01761	ko00270,ko00450,map00270,map00450	-	R00654,R04770	RC00196,RC00348,RC01209,RC01210	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
k141_4831_2	1348635.BBJY01000003_gene3723	4.08e-150	427.0	COG0834@1|root,COG0834@2|Bacteria,1MWDK@1224|Proteobacteria,1RZ89@1236|Gammaproteobacteria,1Y248@135623|Vibrionales	135623|Vibrionales	ET	Ligated ion channel L-glutamate- and glycine-binding site	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
k141_4831_3	1116375.VEJY3_11095	3.13e-168	476.0	COG0765@1|root,COG0765@2|Bacteria,1MX3E@1224|Proteobacteria,1SPYP@1236|Gammaproteobacteria,1Y2TY@135623|Vibrionales	135623|Vibrionales	P	COG0765 ABC-type amino acid transport system, permease component	-	-	-	ko:K02029	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	BPD_transp_1
k141_4831_4	477974.Daud_1137	9.21e-98	292.0	COG1126@1|root,COG1126@2|Bacteria,1TNYD@1239|Firmicutes,247QZ@186801|Clostridia,26082@186807|Peptococcaceae	186801|Clostridia	E	Amino acid ABC transporter ATP-binding protein, PAAT family	glnQ	-	3.6.3.21	ko:K02028	-	M00236	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.3	-	-	ABC_tran
k141_173_1	177439.DP0987	2.23e-34	145.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42MZX@68525|delta/epsilon subdivisions,2X5DK@28221|Deltaproteobacteria,2MQ32@213118|Desulfobacterales	28221|Deltaproteobacteria	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal,dCache_1
k141_3803_1	1191299.AJYX01000053_gene2105	3.18e-71	246.0	COG0704@1|root,COG0840@1|root,COG0704@2|Bacteria,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,1XTM0@135623|Vibrionales	135623|Vibrionales	NT	methyl-accepting chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HBM,MCPsignal
k141_174_2	203122.Sde_2891	0.000176	43.1	COG4994@1|root,COG4994@2|Bacteria,1N9R8@1224|Proteobacteria,1SHTE@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Domain of unknown function (DUF4440)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440
k141_4832_1	1123355.JHYO01000065_gene3709	1.07e-14	81.3	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,2U2KJ@28211|Alphaproteobacteria,3709Y@31993|Methylocystaceae	28211|Alphaproteobacteria	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CZB,MCPsignal,Protoglobin
k141_1444_1	420662.Mpe_A0727	4.73e-34	130.0	COG1835@1|root,COG1835@2|Bacteria,1NIG3@1224|Proteobacteria	1224|Proteobacteria	I	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
k141_1444_2	754436.JCM19237_3644	2.01e-136	409.0	COG1269@1|root,COG1269@2|Bacteria,1MXZG@1224|Proteobacteria,1RQYZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	eight transmembrane protein EpsH	-	-	-	-	-	-	-	-	-	-	-	-	DUF3485,Exosortase_EpsH
k141_1444_3	754436.JCM19237_3645	2.36e-126	374.0	COG0438@1|root,COG0438@2|Bacteria,1MVIM@1224|Proteobacteria,1RPB8@1236|Gammaproteobacteria,1XZAB@135623|Vibrionales	135623|Vibrionales	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4
k141_1444_4	754436.JCM19237_3647	2.21e-174	496.0	COG2348@1|root,COG2348@2|Bacteria,1MXFY@1224|Proteobacteria,1T22W@1236|Gammaproteobacteria	1236|Gammaproteobacteria	V	TIGRFAM FemAB-related protein, PEP-CTERM system-associated	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_6
k141_1444_5	1128912.GMES_0982	2.38e-22	93.2	COG0726@1|root,COG0726@2|Bacteria,1MWMZ@1224|Proteobacteria,1RREJ@1236|Gammaproteobacteria,4663C@72275|Alteromonadaceae	1236|Gammaproteobacteria	G	xylanase chitin deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	DUF3473,Polysacc_deac_1
k141_4496_1	263820.PTO0282	1.13e-24	107.0	COG2025@1|root,arCOG00447@2157|Archaea,2XT06@28890|Euryarchaeota,24204@183967|Thermoplasmata	183967|Thermoplasmata	C	Electron transfer flavoprotein FAD-binding domain	-	-	-	ko:K03522	-	-	-	-	ko00000,ko04147	-	-	-	ETF,ETF_alpha
k141_4496_3	1220534.B655_1421	1.62e-155	451.0	COG1896@1|root,arCOG04311@2157|Archaea,2XVI0@28890|Euryarchaeota	28890|Euryarchaeota	S	HD domain	-	-	-	ko:K07023	-	-	-	-	ko00000	-	-	-	HD_3
k141_4496_4	1121403.AUCV01000074_gene1304	6.69e-39	132.0	COG0640@1|root,COG0640@2|Bacteria,1N19R@1224|Proteobacteria,42TRS@68525|delta/epsilon subdivisions,2WQHU@28221|Deltaproteobacteria,2MMGF@213118|Desulfobacterales	28221|Deltaproteobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_5
k141_4496_5	525897.Dbac_1904	1.06e-232	649.0	COG0701@1|root,COG0701@2|Bacteria,1MUN8@1224|Proteobacteria,42N6E@68525|delta/epsilon subdivisions,2WJXG@28221|Deltaproteobacteria,2M9VF@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Predicted permease	-	-	-	ko:K07089	-	-	-	-	ko00000	-	-	-	ArsP_1
k141_1793_5	870967.VIS19158_13867	4.54e-137	392.0	COG0084@1|root,COG0084@2|Bacteria,1MUC0@1224|Proteobacteria,1SPRE@1236|Gammaproteobacteria,1XUSU@135623|Vibrionales	135623|Vibrionales	L	COG0084 Mg-dependent DNase	tatD	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
k141_1793_7	223926.28805089	0.0	1431.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,1RNBG@1236|Gammaproteobacteria,1XUAZ@135623|Vibrionales	135623|Vibrionales	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
k141_1793_8	672.VV93_v1c12950	2.86e-40	137.0	2B2JB@1|root,31V4J@2|Bacteria,1N4EU@1224|Proteobacteria,1S6JW@1236|Gammaproteobacteria,1XXC5@135623|Vibrionales	135623|Vibrionales	S	Protein of unknown function (DUF2750)	VV1382	-	-	-	-	-	-	-	-	-	-	-	DUF2750
k141_1793_9	243277.VC_A0929	1.35e-144	421.0	COG2265@1|root,COG2265@2|Bacteria,1N8DN@1224|Proteobacteria,1RMX4@1236|Gammaproteobacteria,1XUKQ@135623|Vibrionales	135623|Vibrionales	J	Catalyzes the formation of 5-methyl-uridine at position 747 (m5U747) in 23S rRNA	rlmC	GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0016070,GO:0034641,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360	2.1.1.189	ko:K03212	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	tRNA_U5-meth_tr
k141_1793_10	1348635.BBJY01000016_gene3992	1.56e-123	355.0	COG0218@1|root,COG0218@2|Bacteria,1MY3Z@1224|Proteobacteria,1RNJP@1236|Gammaproteobacteria,1XTW5@135623|Vibrionales	135623|Vibrionales	D	Necessary for normal cell division and for the maintenance of normal septation	engB	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K03978	-	-	-	-	ko00000,ko03036	-	-	-	MMR_HSR1
k141_1793_11	945550.VISI1226_18616	2.24e-103	304.0	COG4106@1|root,COG4106@2|Bacteria,1QUFH@1224|Proteobacteria,1T1X5@1236|Gammaproteobacteria,1XTG8@135623|Vibrionales	135623|Vibrionales	S	2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1, 4-benzoquinol methylase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
k141_1793_12	675816.VIA_000106	6.27e-56	181.0	COG3078@1|root,COG3078@2|Bacteria,1N8HM@1224|Proteobacteria,1SDUG@1236|Gammaproteobacteria,1XWXD@135623|Vibrionales	135623|Vibrionales	S	A GTPase-activating protein (GAP) that modifies Der EngA GTPase function. May play a role in ribosome biogenesis	yihI	-	-	ko:K09894	-	-	-	-	ko00000	-	-	-	YihI
k141_1793_13	870967.VIS19158_08950	4.19e-45	152.0	2E8BZ@1|root,332QM@2|Bacteria,1NAZY@1224|Proteobacteria,1SD7I@1236|Gammaproteobacteria,1XWXQ@135623|Vibrionales	135623|Vibrionales	S	Protein of unknown function (DUF2489)	HD1705	-	-	-	-	-	-	-	-	-	-	-	DUF2489
k141_1793_14	345073.VC395_0064	6.14e-239	668.0	COG0635@1|root,COG0635@2|Bacteria,1MV1I@1224|Proteobacteria,1RN1Y@1236|Gammaproteobacteria,1XT7M@135623|Vibrionales	135623|Vibrionales	H	Belongs to the anaerobic coproporphyrinogen-III oxidase family	hemN	-	1.3.98.3	ko:K02495	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R06895	RC00884	ko00000,ko00001,ko00002,ko01000	-	-	-	HemN_C,Radical_SAM
k141_1793_15	1191299.AJYX01000037_gene3322	3e-140	412.0	COG3071@1|root,COG3071@2|Bacteria,1MU7A@1224|Proteobacteria,1RMRG@1236|Gammaproteobacteria,1XT4E@135623|Vibrionales	135623|Vibrionales	H	enzyme of heme biosynthesis	hemY	-	-	ko:K02498	-	-	-	-	ko00000	-	-	-	HemY_N,TPR_16,TPR_19,TPR_2
k141_1793_16	1348635.BBJY01000016_gene3999	4.22e-99	307.0	COG2959@1|root,COG2959@2|Bacteria,1MY3A@1224|Proteobacteria,1RNJY@1236|Gammaproteobacteria,1XU9X@135623|Vibrionales	135623|Vibrionales	H	Uroporphyrin-III C-methyltransferase	hemX	-	2.1.1.107	ko:K02496	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03194	RC00003,RC00871	ko00000,ko00001,ko00002,ko01000	-	-	-	HemX
k141_1793_17	1219065.VPR01S_25_00040	4.23e-70	222.0	COG1587@1|root,COG1587@2|Bacteria,1MWZD@1224|Proteobacteria,1RM9K@1236|Gammaproteobacteria,1XSK6@135623|Vibrionales	135623|Vibrionales	H	Uroporphyrinogen-III synthase	hemD	-	4.2.1.75	ko:K01719	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03165	RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4
k141_1793_18	945550.VISI1226_16333	2.93e-181	509.0	COG0181@1|root,COG0181@2|Bacteria,1MU56@1224|Proteobacteria,1RMQ8@1236|Gammaproteobacteria,1XSM4@135623|Vibrionales	135623|Vibrionales	H	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps	hemC	GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.61	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084	RC02317	ko00000,ko00001,ko00002,ko01000	-	-	-	Porphobil_deam,Porphobil_deamC
k141_1793_19	55601.VANGNB10_cI0072	0.0	1323.0	COG3072@1|root,COG3072@2|Bacteria,1PI5T@1224|Proteobacteria,1RMPZ@1236|Gammaproteobacteria,1XUEA@135623|Vibrionales	135623|Vibrionales	F	Adenylate cyclase	cyaA	-	4.6.1.1	ko:K05851	ko00230,ko02026,ko05111,map00230,map02026,map05111	-	R00089,R00434	RC00295	ko00000,ko00001,ko01000	-	-	-	Adenyl_cycl_N,Adenylate_cycl
k141_1793_20	55601.VANGNB10_cI0073c	9.3e-52	165.0	COG1965@1|root,COG1965@2|Bacteria,1RH9A@1224|Proteobacteria,1S5UP@1236|Gammaproteobacteria,1XXUN@135623|Vibrionales	135623|Vibrionales	P	Belongs to the frataxin family	cyaY	GO:0003674,GO:0003824,GO:0004322,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006790,GO:0006807,GO:0006873,GO:0006875,GO:0006879,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008198,GO:0008199,GO:0009987,GO:0016043,GO:0016226,GO:0016491,GO:0016530,GO:0016722,GO:0016724,GO:0018282,GO:0018283,GO:0019538,GO:0019725,GO:0022607,GO:0030003,GO:0031163,GO:0033554,GO:0034599,GO:0034986,GO:0036211,GO:0042221,GO:0042592,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0046916,GO:0048037,GO:0048878,GO:0050801,GO:0050896,GO:0051186,GO:0051536,GO:0051537,GO:0051540,GO:0051716,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0071704,GO:0071840,GO:0098771,GO:0140104,GO:1901564	-	ko:K06202	-	-	-	-	ko00000	-	-	-	Frataxin_Cyay
k141_1793_21	1348635.BBJY01000016_gene4004	9.7e-251	694.0	COG0019@1|root,COG0019@2|Bacteria,1MUA6@1224|Proteobacteria,1RMI2@1236|Gammaproteobacteria,1XSWN@135623|Vibrionales	135623|Vibrionales	E	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine	lysA	GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008836,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016831,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
k141_1793_22	55601.VANGNB10_cI0075	7.82e-177	495.0	COG0253@1|root,COG0253@2|Bacteria,1MWDH@1224|Proteobacteria,1RMGV@1236|Gammaproteobacteria,1XSPK@135623|Vibrionales	135623|Vibrionales	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	dapF	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	DAP_epimerase
k141_1793_23	55601.VANGNB10_cI0076	9.4e-90	271.0	COG3159@1|root,COG3159@2|Bacteria,1R4BP@1224|Proteobacteria,1S9SC@1236|Gammaproteobacteria,1Y2KJ@135623|Vibrionales	135623|Vibrionales	S	Protein of unknown function, DUF484	-	-	-	ko:K09921	-	-	-	-	ko00000	-	-	-	DUF484
k141_1793_24	55601.VANGNB10_cI0077	2.93e-180	506.0	COG4973@1|root,COG4973@2|Bacteria,1MUJJ@1224|Proteobacteria,1RMJG@1236|Gammaproteobacteria,1XSJQ@135623|Vibrionales	135623|Vibrionales	D	Belongs to the 'phage' integrase family. XerC subfamily	xerC	GO:0000150,GO:0003674,GO:0003824,GO:0006139,GO:0006259,GO:0006310,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009009,GO:0009987,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140097,GO:1901360	-	ko:K03733	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
k141_1793_25	575788.VS_3044	3.06e-90	273.0	COG1011@1|root,COG1011@2|Bacteria,1N0I6@1224|Proteobacteria,1RQ41@1236|Gammaproteobacteria,1XTVY@135623|Vibrionales	135623|Vibrionales	S	hydrolase (HAD superfamily)	-	-	3.1.3.102,3.1.3.104	ko:K20862	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00548,R07280	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HAD_2
k141_1793_26	1348635.BBJY01000016_gene4009	0.0	904.0	COG2199@1|root,COG2200@1|root,COG3287@1|root,COG2199@2|Bacteria,COG2200@2|Bacteria,COG3287@2|Bacteria,1R5D0@1224|Proteobacteria,1RQJP@1236|Gammaproteobacteria,1XSIC@135623|Vibrionales	135623|Vibrionales	T	FIST_C	-	-	3.1.4.52	ko:K20964	ko05111,map05111	-	-	-	ko00000,ko00001,ko01000	-	-	-	EAL,FIST,FIST_C,GGDEF
k141_1793_27	1348635.BBJY01000016_gene4010	1.34e-53	177.0	COG3148@1|root,COG3148@2|Bacteria,1N8XY@1224|Proteobacteria,1RS6H@1236|Gammaproteobacteria,1XWXG@135623|Vibrionales	135623|Vibrionales	S	DTW	-	-	-	-	-	-	-	-	-	-	-	-	DTW
k141_1793_28	55601.VANGNB10_cI0080c	2.57e-72	234.0	COG3650@1|root,COG3650@2|Bacteria,1RIIM@1224|Proteobacteria,1S8NS@1236|Gammaproteobacteria,1XSAK@135623|Vibrionales	135623|Vibrionales	S	response to hydrogen peroxide	VP2977	-	-	ko:K08985	-	-	-	-	ko00000	-	-	-	-
k141_1793_29	1219065.VPR01S_25_00180	1.94e-125	365.0	COG0561@1|root,COG0561@2|Bacteria,1MV02@1224|Proteobacteria,1RP1D@1236|Gammaproteobacteria,1XTVR@135623|Vibrionales	135623|Vibrionales	S	hydrolases of the HAD superfamily	yigL	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
k141_1793_30	675815.VOA_002869	3.57e-117	348.0	COG2267@1|root,COG2267@2|Bacteria,1MWDA@1224|Proteobacteria,1RRJP@1236|Gammaproteobacteria,1XTME@135623|Vibrionales	135623|Vibrionales	I	Lysophospholipase	pldB	-	3.1.1.5	ko:K01048	ko00564,map00564	-	-	-	ko00000,ko00001,ko01000	-	-	-	Hydrolase_4
k141_1793_31	675815.VOA_002871	2.49e-178	509.0	COG3434@1|root,COG3434@2|Bacteria,1MVW1@1224|Proteobacteria,1RS25@1236|Gammaproteobacteria,1XTJ5@135623|Vibrionales	135623|Vibrionales	T	signal transduction protein containing EAL and modified HD-GYP domains	-	-	3.1.4.52	ko:K07181	ko05111,map05111	-	-	-	ko00000,ko00001,ko01000	-	-	-	EAL,HDOD
k141_1793_32	1219080.VEZ01S_37_00210	1.2e-45	154.0	COG2453@1|root,COG2453@2|Bacteria,1N0H0@1224|Proteobacteria,1S9JV@1236|Gammaproteobacteria,1XWW6@135623|Vibrionales	135623|Vibrionales	T	phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	CDKN3,DSPc
k141_1793_33	675815.VOA_000546	1.42e-169	486.0	COG0477@1|root,COG2814@2|Bacteria,1MV8D@1224|Proteobacteria,1RNF0@1236|Gammaproteobacteria,1XTRW@135623|Vibrionales	135623|Vibrionales	EGP	of the major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
k141_1793_34	1280001.BAOA01000112_gene4648	3.84e-125	369.0	COG3274@1|root,COG3274@2|Bacteria,1MUJ6@1224|Proteobacteria,1S09B@1236|Gammaproteobacteria,1XT5S@135623|Vibrionales	135623|Vibrionales	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
k141_1793_35	1517681.HW45_27665	3.83e-36	127.0	2E6DG@1|root,33113@2|Bacteria,1QJRJ@1224|Proteobacteria,1THSU@1236|Gammaproteobacteria,1XXF8@135623|Vibrionales	135623|Vibrionales	-	-	VP2964	-	-	-	-	-	-	-	-	-	-	-	DUF4145
k141_1793_36	675813.VIB_000080	1.09e-102	301.0	COG2095@1|root,COG2095@2|Bacteria,1N689@1224|Proteobacteria,1RPV0@1236|Gammaproteobacteria,1XTFJ@135623|Vibrionales	135623|Vibrionales	U	UPF0056 membrane protein	-	-	-	ko:K05595	-	-	-	-	ko00000,ko02000	2.A.95.1	-	-	MarC
k141_1793_37	1205908.AKXW01000094_gene2374	3.36e-85	257.0	COG0742@1|root,COG0742@2|Bacteria,1MXKW@1224|Proteobacteria,1RN21@1236|Gammaproteobacteria,1XTTV@135623|Vibrionales	135623|Vibrionales	J	Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle	rsmD	-	2.1.1.171	ko:K08316	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Cons_hypoth95
k141_1793_38	1517681.HW45_27700	5.81e-192	545.0	COG0552@1|root,COG0552@2|Bacteria,1MUDU@1224|Proteobacteria,1RNIN@1236|Gammaproteobacteria,1XUBA@135623|Vibrionales	135623|Vibrionales	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components	ftsY	-	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
k141_1793_39	675815.VOA_002881	3.26e-150	423.0	COG2884@1|root,COG2884@2|Bacteria,1MVQ4@1224|Proteobacteria,1RMZA@1236|Gammaproteobacteria,1XSS6@135623|Vibrionales	135623|Vibrionales	D	Cell division ATP-binding protein FtsE	ftsE	-	-	ko:K09812	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	ABC_tran
k141_1793_40	55601.VANGNB10_cI0103	2.92e-144	416.0	COG2177@1|root,COG2177@2|Bacteria,1MU65@1224|Proteobacteria,1RYBV@1236|Gammaproteobacteria,1XUCE@135623|Vibrionales	135623|Vibrionales	D	Part of the ABC transporter FtsEX involved in cellular division	ftsX	-	-	ko:K09811	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	FtsX
k141_1793_41	674977.VMC_40750	3.07e-169	476.0	COG0568@1|root,COG0568@2|Bacteria,1MVWR@1224|Proteobacteria,1RMFR@1236|Gammaproteobacteria,1XTFM@135623|Vibrionales	135623|Vibrionales	K	RNA polymerase sigma	rpoH	GO:0000988,GO:0000990,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006351,GO:0006352,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016020,GO:0016070,GO:0016987,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031326,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043254,GO:0044087,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1903506,GO:2000112,GO:2000142,GO:2001141	-	ko:K03089	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r4
k141_1793_42	634500.EbC_42170	1.53e-30	111.0	COG0607@1|root,COG0607@2|Bacteria,1MZPW@1224|Proteobacteria,1S94C@1236|Gammaproteobacteria,3X6R9@551|Erwinia	1236|Gammaproteobacteria	H	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide	glpE	GO:0003674,GO:0003824,GO:0004792,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016740,GO:0016782,GO:0016783,GO:0044424,GO:0044464	2.8.1.1	ko:K02439	ko00920,ko01110,ko01120,map00920,map01110,map01120	-	R01931	-	ko00000,ko00001,ko01000	-	-	iECSF_1327.ECSF_3244	Rhodanese
k141_1793_43	55601.VANGNB10_cI0106	1.43e-116	342.0	COG0705@1|root,COG0705@2|Bacteria,1MYPM@1224|Proteobacteria,1RN1K@1236|Gammaproteobacteria,1XSZ8@135623|Vibrionales	135623|Vibrionales	S	membrane protein (homolog of Drosophila rhomboid)	glpG	-	-	ko:K02441	-	-	-	-	ko00000	-	-	-	Rhomboid,Rhomboid_N
k141_1793_44	1219065.VPR01S_25_00400	4.83e-57	181.0	COG1580@1|root,COG1580@2|Bacteria,1N0RT@1224|Proteobacteria,1S9SJ@1236|Gammaproteobacteria,1XXJ9@135623|Vibrionales	135623|Vibrionales	N	Controls the rotational direction of flagella during chemotaxis	-	-	-	ko:K02415	-	-	-	-	ko00000,ko02035	-	-	-	FliL
k141_1793_45	1127673.GLIP_2853	5.69e-10	61.2	COG3161@1|root,COG3161@2|Bacteria	2|Bacteria	H	Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway	ubiC	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008813,GO:0009058,GO:0009108,GO:0009987,GO:0016829,GO:0016830,GO:0016833,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663	4.1.3.40	ko:K03181	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R01302	RC00491,RC02148	ko00000,ko00001,ko00002,ko01000	-	-	iZ_1308.Z5638	Chor_lyase
k141_1793_46	1219065.VPR01S_25_00420	4.5e-155	441.0	COG0382@1|root,COG0382@2|Bacteria,1MV4Q@1224|Proteobacteria,1RMZ1@1236|Gammaproteobacteria,1XT4I@135623|Vibrionales	135623|Vibrionales	H	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate	ubiA	GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008412,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016765,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663	2.5.1.39	ko:K03179	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R05000,R05615	RC00209,RC02895	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
k141_1793_47	1219065.VPR01S_25_00440	8.31e-48	157.0	COG0818@1|root,COG0818@2|Bacteria,1MZ3Q@1224|Proteobacteria,1S92I@1236|Gammaproteobacteria,1XXSV@135623|Vibrionales	135623|Vibrionales	M	Recycling of diacylglycerol produced during the turnover of membrane phospholipid	dgkA	-	2.7.1.107	ko:K00901	ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00561,map00564,map01100,map01110,map04070,map04072,map05231	-	R02240	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	DAGK_prokar
k141_1793_48	223926.28807971	9.26e-124	355.0	COG1974@1|root,COG1974@2|Bacteria,1MW80@1224|Proteobacteria,1RMXF@1236|Gammaproteobacteria,1XV2V@135623|Vibrionales	135623|Vibrionales	K	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair	lexA	GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006282,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0048583,GO:0050789,GO:0050794,GO:0051052,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0080134,GO:0080135,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001020,GO:2001141	3.4.21.88	ko:K01356	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	LexA_DNA_bind,Peptidase_S24
k141_1793_49	223926.28807969	1.32e-200	570.0	COG0534@1|root,COG0534@2|Bacteria,1MV6B@1224|Proteobacteria,1RPGF@1236|Gammaproteobacteria,1XSWY@135623|Vibrionales	135623|Vibrionales	V	Na driven multidrug efflux pump	dinF	-	-	ko:K03327	-	-	-	-	ko00000,ko02000	2.A.66.1	-	-	MatE
k141_1793_51	1187848.AJYQ01000138_gene815	6.86e-59	184.0	2ARMX@1|root,31GYK@2|Bacteria,1RH5N@1224|Proteobacteria,1S68Y@1236|Gammaproteobacteria,1XXAD@135623|Vibrionales	135623|Vibrionales	S	Protein of unknown function (DUF1422)	yijD	-	-	-	-	-	-	-	-	-	-	-	DUF1422
k141_1793_52	1205908.AKXW01000121_gene295	2.2e-281	779.0	COG1292@1|root,COG1292@2|Bacteria,1MV0K@1224|Proteobacteria,1RP3E@1236|Gammaproteobacteria,1XV6I@135623|Vibrionales	135623|Vibrionales	U	Belongs to the BCCT transporter (TC 2.A.15) family	-	-	-	-	-	-	-	-	-	-	-	-	BCCT
k141_1793_53	1219080.VEZ01S_25_00440	3.13e-142	410.0	COG2040@1|root,COG2040@2|Bacteria,1QU2A@1224|Proteobacteria,1RS8M@1236|Gammaproteobacteria,1XSGQ@135623|Vibrionales	135623|Vibrionales	H	COG2040 Homocysteine selenocysteine methylase (S-methylmethionine-dependent)	-	-	-	-	-	-	-	-	-	-	-	-	S-methyl_trans
k141_3154_1	629265.PMA4326_19680	6.63e-20	99.8	COG2931@1|root,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	exsH	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Glyco_hydro_16
k141_1095_2	675806.VII_002367	1.81e-121	377.0	COG3673@1|root,COG3673@2|Bacteria,1QV8K@1224|Proteobacteria,1T29Z@1236|Gammaproteobacteria,1XV7E@135623|Vibrionales	135623|Vibrionales	S	Uncharacterized alpha/beta hydrolase domain (DUF2235)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2235
k141_3814_1	335543.Sfum_0679	2.52e-54	194.0	COG0617@1|root,COG0618@1|root,COG3620@1|root,COG0617@2|Bacteria,COG0618@2|Bacteria,COG3620@2|Bacteria,1MU2X@1224|Proteobacteria,42MJJ@68525|delta/epsilon subdivisions,2WJBN@28221|Deltaproteobacteria,2MQAY@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	tRNA nucleotidyltransferase poly(A) polymerase	ccaA	-	2.7.7.72	ko:K00974	ko03013,map03013	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016	-	-	-	CBS,DHH,DHHA1,PolyA_pol,PolyA_pol_RNAbd
k141_3155_1	1278307.KB907009_gene3376	2.12e-155	443.0	COG0435@1|root,COG0435@2|Bacteria,1MV50@1224|Proteobacteria,1RMTI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	Glutathione S-Transferase	-	-	1.8.5.7	ko:K07393	-	-	-	-	ko00000,ko01000	-	-	-	GST_C_2,GST_N_2
k141_4524_1	1196835.A458_02355	3.84e-51	186.0	COG0845@1|root,COG0845@2|Bacteria,1MUI8@1224|Proteobacteria,1RNK4@1236|Gammaproteobacteria,1YZY7@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	M	COG0845 Membrane-fusion protein	-	-	-	ko:K02022,ko:K16300	-	M00571	-	-	ko00000,ko00002,ko02000,ko02044	8.A.1.3.3	-	-	Biotin_lipoyl_2,HlyD,HlyD_3
k141_1794_2	1304885.AUEY01000033_gene1895	1.99e-16	76.6	2EC3H@1|root,3362D@2|Bacteria,1NDXP@1224|Proteobacteria,42WQJ@68525|delta/epsilon subdivisions,2WRNF@28221|Deltaproteobacteria,2MKWZ@213118|Desulfobacterales	28221|Deltaproteobacteria	S	PilZ domain	-	-	-	-	-	-	-	-	-	-	-	-	PilZ
k141_1794_3	1304885.AUEY01000033_gene1894	3.12e-62	211.0	COG0664@1|root,COG0664@2|Bacteria,1RCF4@1224|Proteobacteria,43BRQ@68525|delta/epsilon subdivisions,2X72K@28221|Deltaproteobacteria,2MJHW@213118|Desulfobacterales	28221|Deltaproteobacteria	T	PFAM Cyclic nucleotide-binding	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388,cNMP_binding
k141_1794_4	96561.Dole_2372	9.51e-106	309.0	COG1100@1|root,COG1100@2|Bacteria,1R6NS@1224|Proteobacteria,42NIX@68525|delta/epsilon subdivisions,2WJ44@28221|Deltaproteobacteria,2MI9K@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Gtr1/RagA G protein conserved region	mglA	GO:0008150,GO:0032879,GO:0032880,GO:0050789,GO:0065007	-	ko:K06883	-	-	-	-	ko00000	-	-	-	Arf
k141_1794_5	1304885.AUEY01000033_gene1892	5.73e-15	73.6	COG3118@1|root,COG3118@2|Bacteria,1REV3@1224|Proteobacteria,42RG6@68525|delta/epsilon subdivisions,2WNPR@28221|Deltaproteobacteria,2MJV2@213118|Desulfobacterales	28221|Deltaproteobacteria	O	belongs to the thioredoxin family	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_1096_1	1304885.AUEY01000064_gene2118	2.09e-316	875.0	COG0481@1|root,COG0481@2|Bacteria,1MVZA@1224|Proteobacteria,42M3D@68525|delta/epsilon subdivisions,2WJEA@28221|Deltaproteobacteria,2MI7F@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,EFG_II,GTP_EFTU,GTP_EFTU_D2,LepA_C
k141_3609_1	1167006.UWK_02868	6e-189	535.0	COG2848@1|root,COG2848@2|Bacteria,1NAFG@1224|Proteobacteria,42NH7@68525|delta/epsilon subdivisions,2WTQT@28221|Deltaproteobacteria,2MN6N@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Uncharacterised ACR (DUF711)	-	-	-	ko:K09157	-	-	-	-	ko00000	-	-	-	DUF711
k141_802_1	991.IW20_13180	1.12e-30	122.0	COG4589@1|root,COG4589@2|Bacteria,4NIPM@976|Bacteroidetes,1HXPT@117743|Flavobacteriia,2NS7C@237|Flavobacterium	976|Bacteroidetes	S	Phosphatidate cytidylyltransferase	cdsA	-	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
k141_587_2	1232437.KL662020_gene753	1.47e-45	170.0	COG0236@1|root,COG0764@1|root,COG3321@1|root,COG4221@1|root,COG0236@2|Bacteria,COG0764@2|Bacteria,COG3321@2|Bacteria,COG4221@2|Bacteria,1R89Z@1224|Proteobacteria,42NGA@68525|delta/epsilon subdivisions,2WJK3@28221|Deltaproteobacteria,2MJ23@213118|Desulfobacterales	28221|Deltaproteobacteria	IQ	TIGRFAM Polyketide-type polyunsaturated fatty acid synthase, PfaA	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_1,FabA,KAsynt_C_assoc,KR,Ketoacyl-synt_C,PP-binding,PS-DH,ketoacyl-synt
k141_305_1	479434.Sthe_1718	5.75e-07	55.8	COG1560@1|root,COG1560@2|Bacteria,2G7BA@200795|Chloroflexi,27Y7M@189775|Thermomicrobia	189775|Thermomicrobia	M	Bacterial lipid A biosynthesis acyltransferase	-	-	2.3.1.241,2.3.1.265	ko:K02517,ko:K22311	ko00540,ko01100,map00540,map01100	M00060	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Lip_A_acyltrans
k141_1938_1	1167006.UWK_02133	1e-44	168.0	COG4191@1|root,COG4191@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
k141_1938_2	443144.GM21_2364	0.000548	43.9	COG2804@1|root,COG3437@1|root,COG2804@2|Bacteria,COG3437@2|Bacteria,1MU7V@1224|Proteobacteria,42M51@68525|delta/epsilon subdivisions,2WKXB@28221|Deltaproteobacteria,43W1A@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	PFAM type II secretion system protein E	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,T2SSE,T2SSE_N
k141_842_2	945543.VIBR0546_02159	1.28e-110	324.0	COG1214@1|root,COG1214@2|Bacteria,1MXPH@1224|Proteobacteria,1RPYX@1236|Gammaproteobacteria,1XTAV@135623|Vibrionales	135623|Vibrionales	O	COG1214 Inactive homolog of metal-dependent proteases	tsaB	-	-	ko:K14742	-	-	-	-	ko00000,ko03016	-	-	-	Peptidase_M22
k141_842_3	1051646.VITU9109_00957	5.78e-29	107.0	2AWHA@1|root,31NDU@2|Bacteria,1QK4W@1224|Proteobacteria,1TI80@1236|Gammaproteobacteria,1XYKX@135623|Vibrionales	135623|Vibrionales	-	-	VV1050	-	-	-	-	-	-	-	-	-	-	-	-
k141_842_4	870967.VIS19158_19552	9.54e-58	186.0	COG3065@1|root,COG3065@2|Bacteria,1MZ8C@1224|Proteobacteria,1S9UB@1236|Gammaproteobacteria,1XX72@135623|Vibrionales	135623|Vibrionales	M	COG3065 Starvation-inducible outer membrane lipoprotein	-	-	-	ko:K07285	-	-	-	-	ko00000	-	-	-	Slp
k141_842_5	1517681.HW45_05345	2.63e-84	261.0	COG2267@1|root,COG2267@2|Bacteria,1QTAP@1224|Proteobacteria,1S6CX@1236|Gammaproteobacteria,1XSDM@135623|Vibrionales	135623|Vibrionales	I	hydrolases or acyltransferases (alpha beta hydrolase superfamily)	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
k141_842_6	1191299.AJYX01000056_gene2687	5.22e-07	50.1	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,1RMQ4@1236|Gammaproteobacteria,1XVCW@135623|Vibrionales	135623|Vibrionales	IQ	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II	fadD	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
k141_3630_1	1348635.BBJY01000002_gene3502	1.42e-187	559.0	COG1330@1|root,COG1330@2|Bacteria,1MWTI@1224|Proteobacteria,1RNT0@1236|Gammaproteobacteria,1XTXU@135623|Vibrionales	135623|Vibrionales	L	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity	recC	-	3.1.11.5	ko:K03583	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_V_gamma
k141_3938_1	1051646.VITU9109_08797	1.45e-29	108.0	COG2914@1|root,COG2914@2|Bacteria,1MZCH@1224|Proteobacteria,1SCHG@1236|Gammaproteobacteria,1XXAY@135623|Vibrionales	135623|Vibrionales	S	Belongs to the UPF0125 (RnfH) family	yfjF	-	-	ko:K09801	-	-	-	-	ko00000	-	-	-	Ub-RnfH
k141_3938_2	243277.VC_0851	1.48e-60	189.0	COG2913@1|root,COG2913@2|Bacteria,1N6YW@1224|Proteobacteria,1SCTT@1236|Gammaproteobacteria,1XXFF@135623|Vibrionales	135623|Vibrionales	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamE	-	-	ko:K06186	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	SmpA_OmlA
k141_1552_1	1265505.ATUG01000001_gene2861	3.55e-148	434.0	COG3829@1|root,COG3829@2|Bacteria,1N1WB@1224|Proteobacteria,42P76@68525|delta/epsilon subdivisions,2WIU6@28221|Deltaproteobacteria,2MIIW@213118|Desulfobacterales	28221|Deltaproteobacteria	KT	Bacterial regulatory protein, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,PAS,PAS_4,PAS_9,Sigma54_activat
k141_588_2	1121904.ARBP01000009_gene4244	0.000723	44.3	COG2207@1|root,COG2207@2|Bacteria,4NRBA@976|Bacteroidetes,47RNM@768503|Cytophagia	976|Bacteroidetes	K	helix-turn-helix- domain containing protein AraC type	-	-	-	-	-	-	-	-	-	-	-	-	Arabinose_bd,HTH_18
k141_306_1	886377.Murru_3008	1.32e-16	79.0	COG0178@1|root,COG0178@2|Bacteria,4NJCU@976|Bacteroidetes,1HZ64@117743|Flavobacteriia	976|Bacteroidetes	L	ATPases associated with a variety of cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
k141_306_2	436717.AOLE_09515	8.93e-66	220.0	COG0178@1|root,COG0178@2|Bacteria,1Q5JE@1224|Proteobacteria,1RSD5@1236|Gammaproteobacteria,3NMIG@468|Moraxellaceae	1236|Gammaproteobacteria	L	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
k141_1940_1	1286171.EAL2_c03100	3.14e-57	189.0	COG5464@1|root,COG5464@2|Bacteria,1UGME@1239|Firmicutes,248B2@186801|Clostridia,25YE1@186806|Eubacteriaceae	186801|Clostridia	S	Putative transposase, YhgA-like	-	-	-	-	-	-	-	-	-	-	-	-	DUF4351,Transposase_31
k141_4654_2	243277.VC_0817	7.79e-188	525.0	COG2801@1|root,COG2801@2|Bacteria,1MWNX@1224|Proteobacteria,1RW9F@1236|Gammaproteobacteria,1Y2TQ@135623|Vibrionales	135623|Vibrionales	L	leucine-zipper of insertion element IS481	-	-	-	-	-	-	-	-	-	-	-	-	HTH_32,rve
k141_5222_1	1265503.KB905161_gene3447	4.76e-137	403.0	COG0438@1|root,COG0438@2|Bacteria,1PHXM@1224|Proteobacteria,1RXIH@1236|Gammaproteobacteria,2Q8E6@267889|Colwelliaceae	1236|Gammaproteobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
k141_3631_1	1206101.AZXC01000024_gene765	1.47e-05	50.8	COG1846@1|root,COG1846@2|Bacteria,2GJ6W@201174|Actinobacteria	201174|Actinobacteria	K	MarR family	-	-	-	-	-	-	-	-	-	-	-	-	MarR_2
k141_3631_2	391615.ABSJ01000046_gene2083	9.6e-48	157.0	COG2050@1|root,COG2050@2|Bacteria,1RJUX@1224|Proteobacteria,1S6IU@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	Thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
k141_3632_1	1304885.AUEY01000006_gene718	1.54e-145	439.0	COG0046@1|root,COG0046@2|Bacteria,1MYN4@1224|Proteobacteria,42M08@68525|delta/epsilon subdivisions,2WITS@28221|Deltaproteobacteria,2MIFX@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C,PurS
k141_3939_1	1027273.GZ77_21225	5.73e-88	276.0	COG5499@1|root,COG5499@2|Bacteria,1MZHS@1224|Proteobacteria,1S4IJ@1236|Gammaproteobacteria,1XM1E@135619|Oceanospirillales	135619|Oceanospirillales	K	transcription regulator containing HTH domain	-	-	-	ko:K18831	-	-	-	-	ko00000,ko02048,ko03000	-	-	-	HTH_3
k141_3939_2	329726.AM1_2100	2.74e-40	135.0	COG4680@1|root,COG4680@2|Bacteria,1G7FY@1117|Cyanobacteria	1117|Cyanobacteria	S	protein conserved in bacteria (DUF2136)	-	-	-	ko:K19166	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HigB_toxin
k141_3939_3	111780.Sta7437_1224	1.36e-22	92.0	COG3809@1|root,COG3809@2|Bacteria,1G6XN@1117|Cyanobacteria,3VK8D@52604|Pleurocapsales	1117|Cyanobacteria	S	Transcription factor zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-TFIIB
k141_5223_1	339671.Asuc_1596	1.56e-145	419.0	28H7K@1|root,2Z7JT@2|Bacteria,1MV01@1224|Proteobacteria,1RSNP@1236|Gammaproteobacteria,1Y8A1@135625|Pasteurellales	135625|Pasteurellales	U	2-keto-3-deoxygluconate permease	-	-	-	ko:K02526	-	-	-	-	ko00000,ko02000	2.A.10.1	-	-	KdgT
k141_1941_1	220341.16503327	2.34e-108	322.0	COG1088@1|root,COG1088@2|Bacteria,1MU5E@1224|Proteobacteria,1RP7G@1236|Gammaproteobacteria,3ZN6R@590|Salmonella	1236|Gammaproteobacteria	M	Polysaccharide biosynthesis protein	rfbB	GO:0000271,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006139,GO:0006629,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008460,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009225,GO:0009226,GO:0009987,GO:0016051,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0033692,GO:0034637,GO:0034641,GO:0034645,GO:0034654,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045226,GO:0046379,GO:0046483,GO:0048037,GO:0050662,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901576,GO:1903509	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	iB21_1397.B21_01936,iECBD_1354.ECBD_1614,iECB_1328.ECB_01947,iECD_1391.ECD_01947,iECIAI39_1322.ECIAI39_0974,iECO26_1355.ECO26_2952,iECSF_1327.ECSF_1930	GDP_Man_Dehyd
k141_1941_2	994573.T472_0204645	9.78e-211	585.0	COG0451@1|root,COG0451@2|Bacteria,1V34Y@1239|Firmicutes,25EDZ@186801|Clostridia,36F9F@31979|Clostridiaceae	186801|Clostridia	GM	3-beta hydroxysteroid dehydrogenase/isomerase family	-	-	5.1.3.2,5.1.3.20,5.1.3.7	ko:K01784,ko:K02473,ko:K03274	ko00052,ko00520,ko00540,ko01100,map00052,map00520,map00540,map01100	M00064,M00361,M00362,M00632	R00291,R00418,R02984,R05176	RC00289,RC01291	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase,GDP_Man_Dehyd
k141_3940_1	177439.DP1923	1.46e-38	134.0	2DZQ5@1|root,32VG0@2|Bacteria,1QWPX@1224|Proteobacteria	1224|Proteobacteria	S	Putative cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Cyclase
k141_3940_2	768706.Desor_3076	5.68e-36	126.0	COG0826@1|root,COG0826@2|Bacteria,1VJN3@1239|Firmicutes,24TRY@186801|Clostridia,2652C@186807|Peptococcaceae	186801|Clostridia	O	Protein of unknown function (DUF3795)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3795
k141_1942_1	459349.CLOAM0417	4.75e-55	185.0	COG0438@1|root,COG0438@2|Bacteria,2NPA0@2323|unclassified Bacteria	2|Bacteria	M	glycosyl transferase group 1	-	-	-	ko:K00754	-	-	-	-	ko00000,ko01000	-	GT4	-	Glyco_transf_4,Glycos_transf_1
k141_843_2	675813.VIB_000257	2.03e-122	357.0	COG0294@1|root,COG0294@2|Bacteria,1MUIR@1224|Proteobacteria,1RM8G@1236|Gammaproteobacteria,1XTE1@135623|Vibrionales	135623|Vibrionales	H	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives	folP	-	2.5.1.15	ko:K00796	ko00790,ko01100,map00790,map01100	M00126,M00841	R03066,R03067	RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
k141_843_3	674977.VMC_37730	5.25e-272	750.0	COG1109@1|root,COG1109@2|Bacteria,1MU24@1224|Proteobacteria,1RMR2@1236|Gammaproteobacteria,1XU1U@135623|Vibrionales	135623|Vibrionales	G	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate	glmM	-	5.4.2.10	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	-	R02060	RC00408	ko00000,ko00001,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
k141_308_1	316275.VSAL_II1032	4.62e-16	74.7	COG0560@1|root,COG0560@2|Bacteria,1RA1A@1224|Proteobacteria,1S21J@1236|Gammaproteobacteria,1XSWS@135623|Vibrionales	135623|Vibrionales	E	COG0560 Phosphoserine phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	HAD
k141_308_2	870967.VIS19158_16046	6.54e-182	513.0	COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,1RMTS@1236|Gammaproteobacteria,1XSM6@135623|Vibrionales	135623|Vibrionales	P	Belongs to the ABC transporter superfamily	-	-	3.6.3.30	ko:K02010,ko:K02052	ko02010,ko02024,map02010,map02024	M00190,M00193	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.10,3.A.1.11	-	-	ABC_tran,TOBE_2
k141_308_3	1116375.VEJY3_16861	1.68e-148	422.0	COG1177@1|root,COG1177@2|Bacteria,1MV4A@1224|Proteobacteria,1RXZZ@1236|Gammaproteobacteria,1XU1G@135623|Vibrionales	135623|Vibrionales	P	COG1177 ABC-type spermidine putrescine transport system, permease component II	-	-	-	ko:K02053	ko02024,map02024	M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11	-	-	BPD_transp_1
k141_308_4	29495.EA26_13690	2.88e-134	387.0	COG4132@1|root,COG4132@2|Bacteria,1NF20@1224|Proteobacteria,1RQAN@1236|Gammaproteobacteria,1XSGA@135623|Vibrionales	135623|Vibrionales	P	transport system permease component	-	-	-	ko:K02054	ko02024,map02024	M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11	-	-	BPD_transp_1
k141_3634_1	177439.DP0373	8.06e-12	69.7	COG1538@1|root,COG1538@2|Bacteria,1NW1T@1224|Proteobacteria	1224|Proteobacteria	MU	Outer membrane efflux protein	czcC	-	-	ko:K15725	-	-	-	-	ko00000,ko02000	1.B.17.2.2	-	-	OEP
k141_5224_1	1304885.AUEY01000012_gene1799	1.31e-53	202.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MC4@68525|delta/epsilon subdivisions,2WIZU@28221|Deltaproteobacteria,2MI2B@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	ABC_sub_bind,GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
k141_3234_1	1265505.ATUG01000003_gene507	1.55e-156	456.0	COG0651@1|root,COG0651@2|Bacteria,1QU5Z@1224|Proteobacteria,42MDX@68525|delta/epsilon subdivisions,2WJ56@28221|Deltaproteobacteria,2MIB7@213118|Desulfobacterales	28221|Deltaproteobacteria	CP	PFAM NADH Ubiquinone plastoquinone (complex I)	-	-	-	ko:K05568	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	Proton_antipo_M,Proton_antipo_N
k141_3234_2	485915.Dret_0791	2.92e-146	435.0	COG0651@1|root,COG0651@2|Bacteria,1MURB@1224|Proteobacteria,42PD3@68525|delta/epsilon subdivisions,2WJ58@28221|Deltaproteobacteria,2MATX@213115|Desulfovibrionales	28221|Deltaproteobacteria	CP	PFAM NADH Ubiquinone plastoquinone (complex I)	-	-	-	ko:K05561,ko:K05568	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	Proton_antipo_M
k141_3234_3	1232437.KL662050_gene5301	7.85e-55	175.0	COG1006@1|root,COG1006@2|Bacteria,1RGU1@1224|Proteobacteria,42SX0@68525|delta/epsilon subdivisions,2WP3K@28221|Deltaproteobacteria,2MKBY@213118|Desulfobacterales	28221|Deltaproteobacteria	P	NADH-ubiquinone/plastoquinone oxidoreductase chain 4L	mnhC	-	-	ko:K05567	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	Oxidored_q2
k141_3234_4	177437.HRM2_35380	1.65e-124	364.0	COG2111@1|root,COG2111@2|Bacteria,1N1CK@1224|Proteobacteria,42S1S@68525|delta/epsilon subdivisions,2WNIJ@28221|Deltaproteobacteria,2MK09@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Domain related to MnhB subunit of Na+/H+ antiporter	mnhB	-	-	ko:K05566	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	MnhB
k141_3234_5	941449.dsx2_1242	8e-22	87.8	COG1563@1|root,COG1563@2|Bacteria,1N5EN@1224|Proteobacteria,42UDW@68525|delta/epsilon subdivisions,2WQK2@28221|Deltaproteobacteria,2MCX6@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	Domain of unknown function (DUF4040)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4040
k141_3234_6	177437.HRM2_35390	1.18e-29	109.0	COG1320@1|root,COG1320@2|Bacteria,1QFGT@1224|Proteobacteria,42W2H@68525|delta/epsilon subdivisions,2WRRI@28221|Deltaproteobacteria,2MKFZ@213118|Desulfobacterales	28221|Deltaproteobacteria	P	TIGRFAM monovalent cation proton antiporter, MnhG PhaG subunit	mnhG	-	-	ko:K05571	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	PhaG_MnhG_YufB
k141_3234_7	177437.HRM2_35400	2.86e-33	117.0	COG2212@1|root,COG2212@2|Bacteria,1N2PU@1224|Proteobacteria,42UDZ@68525|delta/epsilon subdivisions,2WQ3R@28221|Deltaproteobacteria,2MKPG@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Multiple resistance and pH regulation protein F (MrpF / PhaF)	-	-	-	ko:K05570	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	MrpF_PhaF
k141_3234_8	439235.Dalk_4917	1.25e-20	89.7	COG1863@1|root,COG1863@2|Bacteria,1MZYJ@1224|Proteobacteria,42U8N@68525|delta/epsilon subdivisions,2WQSA@28221|Deltaproteobacteria,2MKPM@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Na+/H+ ion antiporter subunit	mnhE	-	-	ko:K05569	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	MNHE
k141_309_1	1167006.UWK_03201	4.39e-36	129.0	COG0589@1|root,COG0589@2|Bacteria,1N9QR@1224|Proteobacteria,42VEI@68525|delta/epsilon subdivisions,2WRFX@28221|Deltaproteobacteria,2MKUR@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
k141_309_2	273121.WS0020	3.48e-49	166.0	COG4887@1|root,COG4887@2|Bacteria,1RCNI@1224|Proteobacteria,43B8A@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	Protein of unknown function (DUF1847)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1847
k141_3635_1	1517681.HW45_12895	2.15e-166	474.0	COG0204@1|root,COG0204@2|Bacteria,1MUFH@1224|Proteobacteria,1RNJQ@1236|Gammaproteobacteria,1XSQX@135623|Vibrionales	135623|Vibrionales	I	Phosphate acyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
k141_1943_1	1304885.AUEY01000014_gene3370	1.65e-122	356.0	COG1432@1|root,COG1432@2|Bacteria,1QC1U@1224|Proteobacteria,42TAH@68525|delta/epsilon subdivisions,2WPYX@28221|Deltaproteobacteria,2MNHU@213118|Desulfobacterales	28221|Deltaproteobacteria	S	NYN domain	-	-	-	-	-	-	-	-	-	-	-	-	NYN
k141_1943_2	1238182.C882_4509	1.7e-44	151.0	COG3542@1|root,COG3542@2|Bacteria,1RHBE@1224|Proteobacteria,2U962@28211|Alphaproteobacteria,2JSSJ@204441|Rhodospirillales	204441|Rhodospirillales	S	Cupin superfamily (DUF985)	-	-	-	ko:K09705	-	-	-	-	ko00000	-	-	-	Cupin_5
k141_2261_1	1540257.JQMW01000009_gene3118	9.48e-146	429.0	COG1114@1|root,COG1114@2|Bacteria,1TQIS@1239|Firmicutes,248I0@186801|Clostridia,36DC1@31979|Clostridiaceae	186801|Clostridia	E	Component of the transport system for branched-chain amino acids	-	-	-	ko:K03311	-	-	-	-	ko00000	2.A.26	-	-	Branch_AA_trans
k141_2261_2	1540257.JQMW01000009_gene3118	7.96e-145	427.0	COG1114@1|root,COG1114@2|Bacteria,1TQIS@1239|Firmicutes,248I0@186801|Clostridia,36DC1@31979|Clostridiaceae	186801|Clostridia	E	Component of the transport system for branched-chain amino acids	-	-	-	ko:K03311	-	-	-	-	ko00000	2.A.26	-	-	Branch_AA_trans
k141_2261_3	536227.CcarbDRAFT_2467	4.62e-183	517.0	COG3426@1|root,COG3426@2|Bacteria,1TPKE@1239|Firmicutes,24993@186801|Clostridia,36GMK@31979|Clostridiaceae	186801|Clostridia	C	PFAM acetate and butyrate kinase	buk	-	2.7.2.7	ko:K00929	ko00650,ko01100,map00650,map01100	-	R01688	RC00002,RC00043	ko00000,ko00001,ko01000	-	-	-	Acetate_kinase
k141_2261_4	1286171.EAL2_808p06620	1.92e-94	281.0	28JAU@1|root,2ZYJS@2|Bacteria,1UPNS@1239|Firmicutes,25HK7@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_2261_5	1123288.SOV_2c04350	3.17e-99	291.0	COG1014@1|root,COG1014@2|Bacteria,1V1DT@1239|Firmicutes,4H4Q5@909932|Negativicutes	909932|Negativicutes	C	Pyruvate ferredoxin/flavodoxin oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	POR
k141_2261_6	1123288.SOV_2c04360	0.0	894.0	COG4231@1|root,COG4231@2|Bacteria,1TNY3@1239|Firmicutes,4H1XI@909932|Negativicutes	909932|Negativicutes	C	Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates	iorA	-	1.2.7.8	ko:K00179	-	-	-	-	br01601,ko00000,ko01000	-	-	-	Fer4,Fer4_21,POR_N,TPP_enzyme_C
k141_4958_1	1517681.HW45_25985	8.01e-17	78.2	COG3732@1|root,COG3732@2|Bacteria,1QJR2@1224|Proteobacteria,1RQY1@1236|Gammaproteobacteria,1XVPG@135623|Vibrionales	135623|Vibrionales	G	Sorbitol phosphotransferase enzyme II N-terminus	-	-	2.7.1.198	ko:K02782,ko:K02783	ko00051,ko02060,map00051,map02060	M00280	R05820	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.4.1	-	-	EIIBC-GUT_C,EIIBC-GUT_N
k141_4958_2	1517681.HW45_25980	2e-52	167.0	COG3731@1|root,COG3731@2|Bacteria,1RK6V@1224|Proteobacteria,1S6MU@1236|Gammaproteobacteria,1XY2A@135623|Vibrionales	135623|Vibrionales	G	PTS system glucitol/sorbitol-specific IIA component	-	-	2.7.1.198	ko:K02781	ko00051,ko02060,map00051,map02060	M00280	R05820	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.4.1	-	-	PTSIIA_gutA
k141_4958_3	1219065.VPR01S_01_02420	8.82e-133	382.0	COG1028@1|root,COG1028@2|Bacteria,1MWSB@1224|Proteobacteria,1RNVJ@1236|Gammaproteobacteria,1XWIW@135623|Vibrionales	135623|Vibrionales	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	srlD	-	1.1.1.140	ko:K00068	ko00051,map00051	-	R05607	RC00085	ko00000,ko00001,ko01000	-	-	-	adh_short
k141_4958_4	1517681.HW45_25970	1.71e-41	140.0	COG4578@1|root,COG4578@2|Bacteria,1RIKE@1224|Proteobacteria,1S7CD@1236|Gammaproteobacteria,1XYGD@135623|Vibrionales	135623|Vibrionales	K	Glucitol operon activator protein (GutM)	-	-	-	ko:K02466	-	-	-	-	ko00000	-	-	-	GutM
k141_4958_5	1517681.HW45_25965	1.61e-122	357.0	COG1349@1|root,COG1349@2|Bacteria,1MUJG@1224|Proteobacteria,1RNW4@1236|Gammaproteobacteria,1XV6U@135623|Vibrionales	135623|Vibrionales	K	DeoR C terminal sensor domain	srlR	-	-	ko:K02468	-	-	-	-	ko00000,ko03000	-	-	-	DeoRC,HTH_DeoR
k141_4958_6	1219065.VPR01S_01_02390	3.36e-93	276.0	COG3730@1|root,COG3730@2|Bacteria,1MXS5@1224|Proteobacteria,1RQTZ@1236|Gammaproteobacteria,1XW65@135623|Vibrionales	135623|Vibrionales	G	PTS system enzyme II sorbitol-specific factor	-	-	-	ko:K02783	ko00051,ko02060,map00051,map02060	M00280	R05820	RC00017,RC03206	ko00000,ko00001,ko00002,ko02000	4.A.4.1	-	-	EII-GUT
k141_4958_7	1517681.HW45_25955	1.42e-159	455.0	COG3732@1|root,COG3732@2|Bacteria,1QJR2@1224|Proteobacteria,1RQY1@1236|Gammaproteobacteria,1XVPG@135623|Vibrionales	1236|Gammaproteobacteria	G	Sorbitol phosphotransferase enzyme II N-terminus	srlE	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0008643,GO:0009401,GO:0015144,GO:0016020,GO:0016740,GO:0016772,GO:0016773,GO:0022804,GO:0022857,GO:0034219,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0090563	2.7.1.198	ko:K02782,ko:K02783	ko00051,ko02060,map00051,map02060	M00280	R05820	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.4.1	-	iEC55989_1330.EC55989_2965,iECIAI1_1343.ECIAI1_2795,iECO103_1326.ECO103_3238,iECO111_1330.ECO111_3421,iECSE_1348.ECSE_2951,iEcE24377_1341.EcE24377A_2987,iUMNK88_1353.UMNK88_3375	EIIBC-GUT_C,EIIBC-GUT_N
k141_4958_8	1201292.DR75_2012	1.94e-22	92.0	COG3731@1|root,COG3731@2|Bacteria,1VG8V@1239|Firmicutes,4HMEK@91061|Bacilli,4B2JX@81852|Enterococcaceae	91061|Bacilli	G	PTS system glucitol/sorbitol-specific IIA component	srlB	-	2.7.1.198	ko:K02781	ko00051,ko02060,map00051,map02060	M00280	R05820	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.4.1	-	-	PTSIIA_gutA
k141_4958_9	998674.ATTE01000001_gene3842	7.32e-110	330.0	COG3177@1|root,COG3177@2|Bacteria,1MV69@1224|Proteobacteria,1RM9J@1236|Gammaproteobacteria,4621I@72273|Thiotrichales	72273|Thiotrichales	S	Fic/DOC family	-	-	-	-	-	-	-	-	-	-	-	-	Fic
k141_5226_1	880072.Desac_1610	2.94e-62	202.0	COG0821@1|root,COG0821@2|Bacteria,1MUAX@1224|Proteobacteria,42M3V@68525|delta/epsilon subdivisions,2WJJ4@28221|Deltaproteobacteria,2MQ70@213462|Syntrophobacterales	28221|Deltaproteobacteria	I	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate	ispG	GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576	1.17.7.1,1.17.7.3	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R08689,R10859	RC01486	ko00000,ko00001,ko00002,ko01000	-	-	-	GcpE
k141_1264_1	55601.VANGNB10_cII0290	2.95e-74	231.0	COG1349@1|root,COG1349@2|Bacteria,1MUJG@1224|Proteobacteria,1RNW4@1236|Gammaproteobacteria,1XV6U@135623|Vibrionales	135623|Vibrionales	K	DeoR C terminal sensor domain	srlR	-	-	ko:K02468	-	-	-	-	ko00000,ko03000	-	-	-	DeoRC,HTH_DeoR
k141_1264_2	1348635.BBJY01000024_gene2194	9.76e-99	306.0	COG0845@1|root,COG0845@2|Bacteria,1MU78@1224|Proteobacteria,1RPI1@1236|Gammaproteobacteria,1XTHC@135623|Vibrionales	135623|Vibrionales	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	acrA	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	Biotin_lipoyl_2,HlyD,HlyD_D23
k141_1264_3	998088.B565_2797	0.0	1394.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,1Y3W3@135624|Aeromonadales	135624|Aeromonadales	V	Efflux pump membrane transporter	-	-	-	ko:K18138	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
k141_1264_4	1397527.Q670_13380	1.02e-109	340.0	COG1538@1|root,COG1538@2|Bacteria,1MUA8@1224|Proteobacteria,1RMDA@1236|Gammaproteobacteria,1XJGR@135619|Oceanospirillales	135619|Oceanospirillales	MU	Outer membrane efflux protein	-	-	-	ko:K18139	ko01501,ko02024,map01501,map02024	M00642,M00643,M00647,M00718,M00768,M00822	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	1.B.17,2.A.6.2	-	-	OEP
k141_1264_5	1001530.BACE01000025_gene1507	1.73e-247	680.0	COG2220@1|root,COG2220@2|Bacteria,1N50Z@1224|Proteobacteria,1RRU3@1236|Gammaproteobacteria,1XUPS@135623|Vibrionales	135623|Vibrionales	S	Beta-lactamase superfamily domain	ulaG	-	-	ko:K03476	ko00053,ko01100,ko01120,map00053,map01100,map01120	M00550	R07677	RC02793	ko00000,ko00001,ko00002,ko01000	-	-	-	Lactamase_B_3
k141_1264_7	243277.VC_A0246	4.93e-238	666.0	COG3037@1|root,COG3414@1|root,COG3037@2|Bacteria,COG3414@2|Bacteria,1MWNR@1224|Proteobacteria,1RP9S@1236|Gammaproteobacteria,1Y2KU@135623|Vibrionales	135623|Vibrionales	G	PTS system sugar-specific permease component	ulaA	-	2.7.1.194	ko:K02822,ko:K03475	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	M00283,M00550	R07671	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.7.1	-	-	EIIC-GAT,PTS_IIB
k141_310_1	748727.CLJU_c39840	3.29e-188	536.0	COG1012@1|root,COG1012@2|Bacteria,1UHQT@1239|Firmicutes,25E5E@186801|Clostridia	186801|Clostridia	C	acetaldehyde dehydrogenase (acetylating)	-	-	-	-	-	-	-	-	-	-	-	-	Aldedh
k141_310_2	1121451.DESAM_21352	3.78e-101	298.0	COG4577@1|root,COG4577@2|Bacteria,1NSAN@1224|Proteobacteria,42YD6@68525|delta/epsilon subdivisions,2WTMY@28221|Deltaproteobacteria,2MAN6@213115|Desulfovibrionales	28221|Deltaproteobacteria	CQ	BMC	-	-	-	-	-	-	-	-	-	-	-	-	BMC
k141_2262_1	870967.VIS19158_12186	1.44e-71	223.0	COG0501@1|root,COG0501@2|Bacteria,1MUNA@1224|Proteobacteria,1RMZ6@1236|Gammaproteobacteria,1XTEI@135623|Vibrionales	135623|Vibrionales	O	Zn-dependent protease with chaperone function	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
k141_2262_2	1517681.HW45_11210	5.17e-69	211.0	COG2050@1|root,COG2050@2|Bacteria,1RGVP@1224|Proteobacteria,1S5WY@1236|Gammaproteobacteria,1XWX9@135623|Vibrionales	135623|Vibrionales	Q	protein possibly involved in aromatic compounds catabolism	ydiI	-	-	-	-	-	-	-	-	-	-	-	4HBT
k141_2262_4	1219076.N646_4258	3.12e-102	313.0	COG4533@1|root,COG4533@2|Bacteria,1N2NK@1224|Proteobacteria,1RP2Z@1236|Gammaproteobacteria,1XUBB@135623|Vibrionales	135623|Vibrionales	K	transport system periplasmic component	sgrR	-	-	ko:K11925	-	-	-	-	ko00000,ko03000	-	-	-	SBP_bac_5,SgrR_N
k141_2263_1	37659.JNLN01000001_gene304	7.67e-96	291.0	COG1228@1|root,COG1228@2|Bacteria,1TP2J@1239|Firmicutes,24AGR@186801|Clostridia,36DRZ@31979|Clostridiaceae	186801|Clostridia	Q	imidazolonepropionase activity	hutI	-	3.5.2.7	ko:K01468	ko00340,ko01100,map00340,map01100	M00045	R02288	RC00683	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1,Amidohydro_3
k141_3637_1	926549.KI421517_gene3365	9.98e-36	148.0	COG2202@1|root,COG3829@1|root,COG4251@1|root,COG2202@2|Bacteria,COG3829@2|Bacteria,COG4251@2|Bacteria,4NFC3@976|Bacteroidetes,47MJ1@768503|Cytophagia	976|Bacteroidetes	T	PAS fold	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,PAS_3,PAS_4,PAS_9
k141_326_1	1307759.JOMJ01000003_gene100	7.83e-96	297.0	COG2262@1|root,COG2262@2|Bacteria,1MUA0@1224|Proteobacteria,42NA6@68525|delta/epsilon subdivisions,2WIMU@28221|Deltaproteobacteria,2M82T@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
k141_2531_1	373903.Hore_21650	1.42e-40	152.0	COG1283@1|root,COG1283@2|Bacteria,1TP4K@1239|Firmicutes,247KT@186801|Clostridia,3WA8D@53433|Halanaerobiales	186801|Clostridia	P	TIGRFAM Na Pi-cotransporter	-	-	-	ko:K03324	-	-	-	-	ko00000,ko02000	2.A.58.2	-	-	Na_Pi_cotrans,PhoU
k141_855_1	1038869.AXAN01000047_gene4471	8.08e-14	67.0	COG1943@1|root,COG1943@2|Bacteria,1P1VG@1224|Proteobacteria,2W7C8@28216|Betaproteobacteria,1KEAW@119060|Burkholderiaceae	28216|Betaproteobacteria	L	Transposase IS66 family	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS66
k141_3953_3	345073.VC395_1113	1.4e-229	639.0	COG0282@1|root,COG0282@2|Bacteria,1MW61@1224|Proteobacteria,1RMKB@1236|Gammaproteobacteria,1XSVG@135623|Vibrionales	135623|Vibrionales	F	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction	ackA1	GO:0003674,GO:0003824,GO:0006091,GO:0006113,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008776,GO:0009987,GO:0015980,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0044237,GO:0055114	2.7.2.1	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00315,R01353	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetate_kinase
k141_3953_4	1238450.VIBNISOn1_600031	1.69e-84	251.0	COG3092@1|root,COG3092@2|Bacteria,1N172@1224|Proteobacteria,1S495@1236|Gammaproteobacteria,1XWYB@135623|Vibrionales	135623|Vibrionales	S	UPF0208 membrane protein	-	-	-	ko:K09899	-	-	-	-	ko00000	-	-	-	DUF412
k141_3953_5	55601.VANGNB10_cI1738c	3.3e-161	459.0	COG2984@1|root,COG2984@2|Bacteria,1MW5D@1224|Proteobacteria,1RR1N@1236|Gammaproteobacteria,1XSVW@135623|Vibrionales	135623|Vibrionales	S	ABC transporter substrate-binding protein	-	-	-	ko:K01989	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_sub_bind
k141_3953_6	1051646.VITU9109_09847	3.35e-66	209.0	COG4120@1|root,COG4120@2|Bacteria,1MXGE@1224|Proteobacteria,1RY3E@1236|Gammaproteobacteria,1XUY5@135623|Vibrionales	135623|Vibrionales	S	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K05832	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	BPD_transp_2
k141_5426_59	1136163.M565_ctg4P074	9.74e-49	164.0	COG3061@1|root,COG3061@2|Bacteria,1R4XK@1224|Proteobacteria,1S2EA@1236|Gammaproteobacteria,1Y2MA@135623|Vibrionales	135623|Vibrionales	M	COG3061 Cell envelope opacity-associated protein A	-	-	-	ko:K07269	-	-	-	-	ko00000	-	-	-	OapA,OapA_N
k141_5426_61	1348635.BBJY01000009_gene1620	1.92e-28	110.0	2C5EJ@1|root,331R8@2|Bacteria,1NDD9@1224|Proteobacteria,1SDIU@1236|Gammaproteobacteria,1XX02@135623|Vibrionales	135623|Vibrionales	S	Protein of unknown function VcgC/VcgE (DUF2780)	PP0330	-	-	-	-	-	-	-	-	-	-	-	DUF2780
k141_5426_63	243277.VC_2570	5.89e-79	235.0	COG0203@1|root,COG0203@2|Bacteria,1RCWN@1224|Proteobacteria,1S3QK@1236|Gammaproteobacteria,1XWW2@135623|Vibrionales	135623|Vibrionales	J	Ribosomal protein L17	rplQ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02879	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L17
k141_1395_3	429009.Adeg_0304	3.04e-106	321.0	COG0709@1|root,COG0709@2|Bacteria,1TQCJ@1239|Firmicutes,247NS@186801|Clostridia,42ENJ@68295|Thermoanaerobacterales	186801|Clostridia	F	Synthesizes selenophosphate from selenide and ATP	selD	-	2.7.9.3	ko:K01008	ko00450,ko01100,map00450,map01100	-	R03595	RC00002,RC02878	ko00000,ko00001,ko01000,ko03016	-	-	-	AIRS,AIRS_C
k141_381_2	411459.RUMOBE_03042	1.1e-08	58.9	COG0622@1|root,COG0622@2|Bacteria,1VA0U@1239|Firmicutes,24MMK@186801|Clostridia,3Y05G@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	yfcE1	-	-	ko:K07095	-	-	-	-	ko00000	-	-	-	Metallophos_2
k141_1742_2	223926.28807509	1.12e-170	482.0	COG1131@1|root,COG1131@2|Bacteria,1MUW7@1224|Proteobacteria,1RMC5@1236|Gammaproteobacteria,1XSXH@135623|Vibrionales	135623|Vibrionales	V	COG1131 ABC-type multidrug transport system, ATPase component	yadG	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
k141_4437_2	1348635.BBJY01000008_gene1708	1.69e-219	611.0	COG0287@1|root,COG1605@1|root,COG0287@2|Bacteria,COG1605@2|Bacteria,1MVUT@1224|Proteobacteria,1RQB3@1236|Gammaproteobacteria,1XUE1@135623|Vibrionales	135623|Vibrionales	E	T-protein	tyrA	-	1.3.1.12,5.4.99.5	ko:K14187	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00024,M00025	R01715,R01728	RC00125,RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	CM_2,PDH
k141_4437_3	243277.VC_0697	9.49e-44	147.0	2E3XG@1|root,32YUI@2|Bacteria,1N8RF@1224|Proteobacteria,1SCJ3@1236|Gammaproteobacteria,1XYEY@135623|Vibrionales	135623|Vibrionales	S	Binds the second messenger bis-(3'-5') cyclic dimeric guanosine monophosphate (c-di-GMP). Can bind two c-di-GMP molecules per monomer. May play a role in bacterial second- messenger regulated processes. Binding to c-di-GMP induces a conformational change of the C- and N-termini resulting in the exposure of a highly negative surface on one side of the protein to a	-	-	-	-	-	-	-	-	-	-	-	-	PilZ
k141_4437_4	29495.EA26_03610	0.0	1020.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,1RPWS@1236|Gammaproteobacteria,1XSGT@135623|Vibrionales	135623|Vibrionales	S	COG0488 ATPase components of ABC transporters with duplicated ATPase domains	yjjK	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,ABC_tran_Xtn
k141_4437_5	675815.VOA_003152	5.09e-199	581.0	COG0741@1|root,COG0741@2|Bacteria,1MV3F@1224|Proteobacteria,1RMS8@1236|Gammaproteobacteria,1XUVC@135623|Vibrionales	135623|Vibrionales	M	COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)	slt	-	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	SLT,SLT_L
k141_4437_6	243277.VC_0701	2.17e-37	129.0	COG2973@1|root,COG2973@2|Bacteria,1MYB2@1224|Proteobacteria,1S6RH@1236|Gammaproteobacteria,1XYA5@135623|Vibrionales	135623|Vibrionales	K	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon and prevents the initiation of transcription	trpR	GO:0003674,GO:0003700,GO:0006082,GO:0006355,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009072,GO:0009308,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0019752,GO:0031323,GO:0031326,GO:0034641,GO:0042430,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0140110,GO:1901360,GO:1901564,GO:1901605,GO:1903506,GO:2000112,GO:2001141	-	ko:K03720	-	-	-	-	ko00000,ko03000	-	-	-	Trp_repressor
k141_4437_7	29495.EA26_03625	6.62e-73	224.0	COG1986@1|root,COG1986@2|Bacteria,1RG2E@1224|Proteobacteria,1S5QG@1236|Gammaproteobacteria,1XUT8@135623|Vibrionales	135623|Vibrionales	F	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions	yjjX	GO:0003674,GO:0003824,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111	-	-	-	-	-	-	-	-	-	-	NTPase_I-T
k141_4437_8	675815.VOA_003149	5.81e-60	205.0	COG5001@1|root,COG5001@2|Bacteria,1PRV9@1224|Proteobacteria,1RZHM@1236|Gammaproteobacteria,1XSCI@135623|Vibrionales	135623|Vibrionales	T	COG2199 FOG GGDEF domain	mbaA	GO:0007154,GO:0007165,GO:0008150,GO:0009987,GO:0023052,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007	3.1.4.52	ko:K20966	ko05111,map05111	-	-	-	ko00000,ko00001,ko01000	-	-	-	EAL,GGDEF
k141_2751_2	411459.RUMOBE_01714	3.38e-48	159.0	COG4824@1|root,COG4824@2|Bacteria,1V934@1239|Firmicutes,24MXR@186801|Clostridia,3Y0R2@572511|Blautia	186801|Clostridia	S	Bacteriophage holin family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_holin_4_1
k141_2751_3	634956.Geoth_0802	1.55e-13	64.7	295QT@1|root,2ZT24@2|Bacteria,1W3AA@1239|Firmicutes,4I08M@91061|Bacilli,1WHPP@129337|Geobacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_2751_5	1280692.AUJL01000004_gene832	2.01e-38	146.0	COG3266@1|root,COG3266@2|Bacteria,1UNJR@1239|Firmicutes,25HET@186801|Clostridia,36VAC@31979|Clostridiaceae	186801|Clostridia	S	Siphovirus ReqiPepy6 Gp37-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Collagen,Sipho_Gp37
k141_4438_1	1348635.BBJY01000005_gene3349	7.29e-100	311.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,1THIN@1236|Gammaproteobacteria,1XW5G@135623|Vibrionales	135623|Vibrionales	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,dCache_1
k141_4438_2	1348635.BBJY01000006_gene489	4.83e-96	287.0	COG0583@1|root,COG0583@2|Bacteria,1MVJ7@1224|Proteobacteria,1RMNJ@1236|Gammaproteobacteria,1Y0A5@135623|Vibrionales	135623|Vibrionales	K	Bacterial regulatory helix-turn-helix protein, lysR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
k141_383_1	243277.VC_A1080	2.61e-31	120.0	COG0845@1|root,COG0845@2|Bacteria,1MUI8@1224|Proteobacteria,1RNK4@1236|Gammaproteobacteria,1XSCT@135623|Vibrionales	135623|Vibrionales	M	COG0845 Membrane-fusion protein	lapC	-	-	ko:K12542	-	M00330	-	-	ko00000,ko00002,ko02000,ko02044	3.A.1.109.4,8.A.1	-	-	Biotin_lipoyl_2,HlyD,HlyD_3,OEP
k141_383_2	675815.VOA_001102	3.61e-126	362.0	COG0259@1|root,COG0259@2|Bacteria,1NZUU@1224|Proteobacteria,1RMQ2@1236|Gammaproteobacteria,1XUNP@135623|Vibrionales	135623|Vibrionales	H	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP)	pdxH	GO:0003674,GO:0003824,GO:0004733,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016491,GO:0016638,GO:0016641,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046184,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	1.4.3.5	ko:K00275	ko00750,ko01100,ko01120,map00750,map01100,map01120	M00124	R00277,R00278,R01710,R01711	RC00048,RC00116	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_phzG_C,Putative_PNPOx
k141_383_3	55601.VANGNB10_cII0995	7.09e-162	476.0	COG1262@1|root,COG1262@2|Bacteria,1NQ5K@1224|Proteobacteria,1RQVK@1236|Gammaproteobacteria,1XU7A@135623|Vibrionales	135623|Vibrionales	S	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,PEGA
k141_1052_2	1051646.VITU9109_04992	0.0	1196.0	COG2766@1|root,COG2766@2|Bacteria,1MVW7@1224|Proteobacteria,1RNFJ@1236|Gammaproteobacteria,1XT8T@135623|Vibrionales	135623|Vibrionales	T	Serine protein kinase	prkA	-	-	ko:K07180	-	-	-	-	ko00000	-	-	-	AAA_PrkA,PrkA
k141_1052_3	675814.VIC_001567	1.26e-249	691.0	COG2718@1|root,COG2718@2|Bacteria,1MWQM@1224|Proteobacteria,1RQWC@1236|Gammaproteobacteria,1XSXD@135623|Vibrionales	135623|Vibrionales	S	Belongs to the UPF0229 family	yeaH	-	-	ko:K09786	-	-	-	-	ko00000	-	-	-	DUF444
k141_1052_5	345073.VC395_1990	7.92e-130	374.0	COG1212@1|root,COG1212@2|Bacteria,1MUUU@1224|Proteobacteria,1RMAE@1236|Gammaproteobacteria,1XTK4@135623|Vibrionales	135623|Vibrionales	M	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria	kdsB	GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008690,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016772,GO:0016779,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0046401,GO:0070567,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509	2.7.7.38	ko:K00979	ko00540,ko01100,map00540,map01100	M00063	R03351,R11396	RC00152,RC00910	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_3
k141_1052_6	345073.VC395_1991	2.36e-33	115.0	COG2835@1|root,COG2835@2|Bacteria,1N6Y2@1224|Proteobacteria,1SCFF@1236|Gammaproteobacteria,1XYYD@135623|Vibrionales	135623|Vibrionales	S	Belongs to the UPF0434 family	-	-	-	ko:K09791	-	-	-	-	ko00000	-	-	-	Trm112p
k141_1052_7	1187848.AJYQ01000085_gene883	1.46e-79	248.0	COG1663@1|root,COG1663@2|Bacteria,1MU8G@1224|Proteobacteria,1RMMW@1236|Gammaproteobacteria,1XU8K@135623|Vibrionales	135623|Vibrionales	F	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA)	lpxK	GO:0003674,GO:0003824,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009029,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	2.7.1.130	ko:K00912	ko00540,ko01100,map00540,map01100	M00060	R04657	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	LpxK
k141_1743_1	1454202.PPBDW_10016___1	7.25e-19	85.1	COG0666@1|root,COG0666@2|Bacteria,1NMUY@1224|Proteobacteria	1224|Proteobacteria	S	Ankyrin repeat	-	-	-	-	-	-	-	-	-	-	-	-	Ank_2,Ank_3,Ank_4
k141_1743_2	1051646.VITU9109_23100	9.23e-48	154.0	COG0633@1|root,COG0633@2|Bacteria,1QU91@1224|Proteobacteria,1T1VI@1236|Gammaproteobacteria,1XXYP@135623|Vibrionales	135623|Vibrionales	C	COG0633 Ferredoxin	-	-	-	ko:K11107	-	-	-	-	ko00000	-	-	-	Fer2
k141_1743_3	243277.VC_1255	1.25e-254	701.0	COG0208@1|root,COG0208@2|Bacteria,1MWUS@1224|Proteobacteria,1RMJC@1236|Gammaproteobacteria,1XSHZ@135623|Vibrionales	135623|Vibrionales	F	COG0208 Ribonucleotide reductase, beta subunit	nrdB	-	1.17.4.1	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_sm
k141_1743_4	945550.VISI1226_04190	0.0	914.0	COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,1RMPV@1236|Gammaproteobacteria,1XTXI@135623|Vibrionales	135623|Vibrionales	F	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides	nrdA	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	ATP-cone,Ribonuc_red_lgC,Ribonuc_red_lgN
k141_71_1	1304885.AUEY01000002_gene341	2.4e-301	838.0	COG0465@1|root,COG0465@2|Bacteria,1MU6J@1224|Proteobacteria,42M4Z@68525|delta/epsilon subdivisions,2WJ0D@28221|Deltaproteobacteria,2MIPH@213118|Desulfobacterales	28221|Deltaproteobacteria	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
k141_71_2	868864.Dester_0390	1.27e-80	255.0	COG0294@1|root,COG0294@2|Bacteria,2G3IT@200783|Aquificae	200783|Aquificae	H	dihydropteroate synthase	folP	-	2.5.1.15	ko:K00796	ko00790,ko01100,map00790,map01100	M00126,M00841	R03066,R03067	RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
k141_71_3	177437.HRM2_05030	2.84e-101	302.0	COG1521@1|root,COG1521@2|Bacteria,1MUYA@1224|Proteobacteria,42MVZ@68525|delta/epsilon subdivisions,2WJ3N@28221|Deltaproteobacteria,2MJ6S@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis	coaX	-	2.7.1.33	ko:K03525	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1986	Pan_kinase
k141_71_5	1304885.AUEY01000022_gene3395	2.29e-174	496.0	COG2805@1|root,COG2805@2|Bacteria,1MU3J@1224|Proteobacteria,42M7F@68525|delta/epsilon subdivisions,2WJ4Z@28221|Deltaproteobacteria,2MHXJ@213118|Desulfobacterales	28221|Deltaproteobacteria	NU	PFAM type II secretion system protein E	pilT1	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
k141_3763_2	237609.PSAKL28_03370	1.1e-27	106.0	2ASWM@1|root,32ZGF@2|Bacteria,1ND0U@1224|Proteobacteria,1SRDQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF3010)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3010
k141_3763_4	1280001.BAOA01000111_gene4674	1.18e-54	171.0	COG2026@1|root,COG2026@2|Bacteria,1MZ76@1224|Proteobacteria,1S8RR@1236|Gammaproteobacteria,1XXSK@135623|Vibrionales	135623|Vibrionales	DJ	Cytotoxic translational repressor of toxin-antitoxin stability system	-	-	-	ko:K06218	-	-	-	-	ko00000,ko02048	-	-	-	ParE_toxin
k141_3763_5	1280001.BAOA01000111_gene4675	6.19e-46	148.0	COG2161@1|root,COG2161@2|Bacteria,1N6YR@1224|Proteobacteria,1S8RK@1236|Gammaproteobacteria,1XY1J@135623|Vibrionales	135623|Vibrionales	D	Antitoxin component of a toxin-antitoxin (TA) module	-	-	-	ko:K18923	-	-	-	-	ko00000,ko02048	-	-	-	PhdYeFM_antitox
k141_3763_8	1187848.AJYQ01000047_gene651	1.32e-76	238.0	COG3547@1|root,COG3547@2|Bacteria,1MUER@1224|Proteobacteria,1RMAQ@1236|Gammaproteobacteria,1XVPF@135623|Vibrionales	135623|Vibrionales	L	COG3547 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k141_3763_9	1280001.BAOA01000278_gene4318	1.41e-47	153.0	COG2161@1|root,COG2161@2|Bacteria,1RJZX@1224|Proteobacteria,1S6BY@1236|Gammaproteobacteria,1XY19@135623|Vibrionales	135623|Vibrionales	D	Antitoxin component of a toxin-antitoxin (TA) module	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
k141_3763_10	1219065.VPR01S_08_00120	0.000117	42.4	COG3668@1|root,COG3668@2|Bacteria,1N5BN@1224|Proteobacteria,1T0X0@1236|Gammaproteobacteria,1Y309@135623|Vibrionales	135623|Vibrionales	S	ParE toxin of type II toxin-antitoxin system, parDE	-	-	-	-	-	-	-	-	-	-	-	-	ParE_toxin
k141_3763_11	314292.VAS14_03083	2.07e-66	207.0	COG5628@1|root,COG5628@2|Bacteria,1N5X7@1224|Proteobacteria,1SEK0@1236|Gammaproteobacteria,1XXUW@135623|Vibrionales	135623|Vibrionales	S	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
k141_3763_12	675816.VIA_002728	7.88e-46	155.0	COG3755@1|root,COG3755@2|Bacteria,1RI41@1224|Proteobacteria,1S7YE@1236|Gammaproteobacteria,1XXP9@135623|Vibrionales	135623|Vibrionales	S	Lysozyme inhibitor LprI	-	-	-	-	-	-	-	-	-	-	-	-	LprI
k141_3763_13	888059.HMPREF9071_1675	8.19e-89	270.0	COG0596@1|root,COG0596@2|Bacteria,4PGTE@976|Bacteroidetes,1IHJZ@117743|Flavobacteriia,1ESZD@1016|Capnocytophaga	976|Bacteroidetes	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_3763_14	1122212.AULO01000011_gene337	8.08e-43	142.0	COG3668@1|root,COG3668@2|Bacteria,1N4FP@1224|Proteobacteria,1SBVT@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	ParE toxin of type II toxin-antitoxin system, parDE	-	-	-	ko:K19092	-	-	-	-	ko00000,ko02048	-	-	-	ParE_toxin
k141_3763_15	672.VV93_v1c16650	7.08e-42	138.0	COG2161@1|root,COG2161@2|Bacteria,1N8HI@1224|Proteobacteria,1SCTG@1236|Gammaproteobacteria,1XYG4@135623|Vibrionales	135623|Vibrionales	D	Antitoxin component of a toxin-antitoxin (TA) module	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
k141_3763_17	94122.Shewana3_1860	8.55e-17	76.3	COG1077@1|root,COG1077@2|Bacteria,1RK8H@1224|Proteobacteria,1S8CX@1236|Gammaproteobacteria,2QCYW@267890|Shewanellaceae	1236|Gammaproteobacteria	D	MreB/Mbl protein	-	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
k141_3763_18	1123518.ARWI01000001_gene232	2.14e-147	416.0	COG0110@1|root,COG0110@2|Bacteria,1MUCJ@1224|Proteobacteria,1RPPT@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	COG0110 Acetyltransferase (isoleucine patch superfamily)	sat	-	-	ko:K18234	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	Hexapep
k141_3763_19	223926.28806789	3.83e-59	185.0	COG0251@1|root,COG0251@2|Bacteria,1N2XR@1224|Proteobacteria,1S4QP@1236|Gammaproteobacteria,1XY94@135623|Vibrionales	135623|Vibrionales	J	translation initiation inhibitor, yjgF family	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
k141_3763_20	591159.ACEZ01000201_gene2552	2.12e-23	92.8	COG2350@1|root,COG2350@2|Bacteria,2GRVC@201174|Actinobacteria	201174|Actinobacteria	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
k141_3763_22	29495.EA26_14715	0.000472	41.6	2DNNV@1|root,32YCB@2|Bacteria,1N7IN@1224|Proteobacteria,1S9V9@1236|Gammaproteobacteria,1XXWX@135623|Vibrionales	135623|Vibrionales	S	CcdB protein	-	-	-	ko:K19163	-	-	-	-	ko00000,ko02048	-	-	-	CcdB
k141_3763_23	339670.Bamb_4153	1.98e-70	215.0	2AGFY@1|root,316NA@2|Bacteria,1PXT7@1224|Proteobacteria,2WD4W@28216|Betaproteobacteria,1K9D3@119060|Burkholderiaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_3763_25	1122194.AUHU01000003_gene2408	8.19e-267	783.0	COG3507@1|root,COG3693@1|root,COG5297@1|root,COG3507@2|Bacteria,COG3693@2|Bacteria,COG5297@2|Bacteria,1R7BZ@1224|Proteobacteria,1S17S@1236|Gammaproteobacteria,466TT@72275|Alteromonadaceae	1236|Gammaproteobacteria	G	Glycosyl hydrolase family 10	-	-	-	-	-	-	-	-	-	-	-	-	CBM_2,CBM_4_9,CBM_6,Glyco_hydro_10,Glyco_hydro_43
k141_3763_26	509191.AEDB02000034_gene2315	6.62e-58	212.0	COG0296@1|root,COG2730@1|root,COG3291@1|root,COG4193@1|root,COG4733@1|root,COG0296@2|Bacteria,COG2730@2|Bacteria,COG3291@2|Bacteria,COG4193@2|Bacteria,COG4733@2|Bacteria,1U53B@1239|Firmicutes,25KDY@186801|Clostridia,3WNUI@541000|Ruminococcaceae	186801|Clostridia	G	Carbohydrate binding module (family 6)	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,Cellulase,Dockerin_1
k141_3763_27	676032.FN3523_0008	1.02e-14	80.9	COG0697@1|root,COG0697@2|Bacteria,1MZQM@1224|Proteobacteria,1SZQ8@1236|Gammaproteobacteria,462M8@72273|Thiotrichales	72273|Thiotrichales	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
k141_3763_28	1190606.AJYG01000193_gene2600	5.49e-242	680.0	COG0747@1|root,COG0747@2|Bacteria,1QJEA@1224|Proteobacteria,1THDP@1236|Gammaproteobacteria,1XUE8@135623|Vibrionales	135623|Vibrionales	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
k141_3763_29	931626.Awo_c07570	2.08e-07	63.5	COG0840@1|root,COG3850@1|root,COG0840@2|Bacteria,COG3850@2|Bacteria,1TP5A@1239|Firmicutes,247S3@186801|Clostridia,25VY7@186806|Eubacteriaceae	186801|Clostridia	NT	Methyl-accepting chemotaxis protein (MCP) signaling domain	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal,dCache_1
k141_3763_30	203122.Sde_3061	0.0	920.0	COG0726@1|root,COG0726@2|Bacteria,1R7W4@1224|Proteobacteria,1RXZE@1236|Gammaproteobacteria,468DS@72275|Alteromonadaceae	1236|Gammaproteobacteria	G	Polysaccharide deacetylase	xyn11B	-	-	-	-	-	-	-	-	-	-	-	CBM60,CBM_10,CBM_5_12_2,Glyco_hydro_11,Malectin,Polysacc_deac_1
k141_3763_31	1209072.ALBT01000017_gene4188	2.32e-26	105.0	COG0657@1|root,COG0657@2|Bacteria,1R6QH@1224|Proteobacteria,1S036@1236|Gammaproteobacteria,1FFX0@10|Cellvibrio	1236|Gammaproteobacteria	I	Carboxylesterase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3
k141_3419_2	1348635.BBJY01000010_gene1439	1.02e-92	277.0	COG2188@1|root,COG2188@2|Bacteria,1MUEB@1224|Proteobacteria,1RN2J@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	transcriptional regulator	yidP	GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0006810,GO:0008150,GO:0008152,GO:0008643,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044464,GO:0046483,GO:0051179,GO:0051234,GO:0071702,GO:0071704,GO:0071944,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576	-	ko:K03482,ko:K03710,ko:K11922	-	-	-	-	ko00000,ko03000	-	-	-	GntR,UTRA
k141_3419_3	1348635.BBJY01000006_gene370	6.06e-94	280.0	COG1280@1|root,COG1280@2|Bacteria,1RA1G@1224|Proteobacteria,1RSYH@1236|Gammaproteobacteria,1XW8H@135623|Vibrionales	135623|Vibrionales	E	LysE type translocator	-	-	-	ko:K11250	-	-	-	-	ko00000,ko02000	2.A.76.1.5	-	-	LysE
k141_3419_4	1042375.AFPL01000012_gene696	2.43e-79	237.0	COG3791@1|root,COG3791@2|Bacteria,1N0W7@1224|Proteobacteria,1S5AN@1236|Gammaproteobacteria,4699S@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Glutathione-dependent formaldehyde-activating enzyme	-	-	-	-	-	-	-	-	-	-	-	-	GFA
k141_3419_5	1301098.PKB_1117	1.24e-12	75.1	COG0583@1|root,COG0583@2|Bacteria,1MU3N@1224|Proteobacteria,1RSDJ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	transcriptional regulator	cynR_1	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
k141_723_1	1188252.AJYK01000022_gene1409	4.41e-45	151.0	COG0724@1|root,COG0724@2|Bacteria,1N0P8@1224|Proteobacteria,1S987@1236|Gammaproteobacteria,1XWU8@135623|Vibrionales	135623|Vibrionales	S	COG0724 RNA-binding proteins (RRM domain)	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
k141_723_2	243277.VC_0158	1.11e-99	299.0	COG0796@1|root,COG0796@2|Bacteria,1NAI2@1224|Proteobacteria,1RPU9@1236|Gammaproteobacteria,1XTNA@135623|Vibrionales	135623|Vibrionales	M	Provides the (R)-glutamate required for cell wall biosynthesis	murI	GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008881,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016853,GO:0016854,GO:0016855,GO:0030203,GO:0034645,GO:0036361,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0047661,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	5.1.1.3	ko:K01776	ko00471,ko01100,map00471,map01100	-	R00260	RC00302	ko00000,ko00001,ko01000,ko01011	-	-	-	Asp_Glu_race
k141_723_3	1219077.VAZ01S_082_00050	8.21e-211	589.0	COG2265@1|root,COG2265@2|Bacteria,1MY45@1224|Proteobacteria,1RN2B@1236|Gammaproteobacteria,1XSB1@135623|Vibrionales	135623|Vibrionales	J	Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA)	trmA	GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360	2.1.1.35	ko:K00557	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA_U5-meth_tr
k141_723_5	1005999.GLGR_0494	8.69e-205	593.0	COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,1RMHY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	transcriptional regulator	-	-	-	ko:K11914	-	-	-	-	ko00000,ko02044,ko03000	-	-	-	HTH_8,PrpR_N,Sigma54_activat
k141_723_6	1218086.BBNB01000003_gene2401	6.6e-182	517.0	COG3964@1|root,COG3964@2|Bacteria,1PH8X@1224|Proteobacteria,1SZS4@1236|Gammaproteobacteria,3WZBT@544|Citrobacter	1236|Gammaproteobacteria	S	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,Amidohydro_3
k141_723_7	1005999.GLGR_0492	4.96e-249	693.0	COG0471@1|root,COG0471@2|Bacteria,1MUSA@1224|Proteobacteria,1RMF3@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	transporter	-	-	-	ko:K03319	-	-	-	-	ko00000	2.A.47	-	-	Na_sulph_symp
k141_723_8	66269.NL54_09240	2.48e-126	363.0	COG0684@1|root,COG0684@2|Bacteria,1MW9P@1224|Proteobacteria,1RNV3@1236|Gammaproteobacteria,3W0HD@53335|Pantoea	1236|Gammaproteobacteria	H	Aldolase/RraA	-	-	-	-	-	-	-	-	-	-	-	-	RraA-like
k141_1744_1	1304885.AUEY01000116_gene2850	3.32e-17	82.0	COG2223@1|root,COG2223@2|Bacteria,1QUK3@1224|Proteobacteria,43BJX@68525|delta/epsilon subdivisions,2X6XT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	PFAM Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
k141_2752_1	96561.Dole_2166	2.98e-87	263.0	COG0177@1|root,COG0177@2|Bacteria,1MUYQ@1224|Proteobacteria,42R18@68525|delta/epsilon subdivisions,2WN0H@28221|Deltaproteobacteria,2MIQV@213118|Desulfobacterales	28221|Deltaproteobacteria	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	-	3.1.11.2,4.2.99.18	ko:K01142,ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,Exo_endo_phos,HhH-GPD
k141_2752_2	994573.T472_0203985	2.8e-64	205.0	COG3634@1|root,COG3634@2|Bacteria,1V40Z@1239|Firmicutes,24JKA@186801|Clostridia,36I22@31979|Clostridiaceae	186801|Clostridia	O	Thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_3
k141_2752_3	269482.Bcep1808_4653	1.57e-84	271.0	COG3634@1|root,COG3634@2|Bacteria,1MUKD@1224|Proteobacteria,2VJ01@28216|Betaproteobacteria,1K1YC@119060|Burkholderiaceae	28216|Betaproteobacteria	C	alkyl hydroperoxide reductase	ahpF	-	-	ko:K03387	-	-	-	-	ko00000,ko01000	-	-	-	Pyr_redox_2,Thioredoxin_3
k141_2752_4	288705.RSal33209_0306	9.81e-11	65.1	COG1473@1|root,COG1473@2|Bacteria,2GK05@201174|Actinobacteria,1W7X1@1268|Micrococcaceae	201174|Actinobacteria	S	Peptidase family M20/M25/M40	amiA	-	-	ko:K01436,ko:K06048	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
k141_4439_1	755732.Fluta_2712	0.000971	41.6	COG0124@1|root,COG0124@2|Bacteria,4NE8N@976|Bacteroidetes,1HX0E@117743|Flavobacteriia,2PAIB@246874|Cryomorphaceae	976|Bacteroidetes	J	tRNA synthetase class II core domain (G, H, P, S and T)	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
k141_4439_2	177437.HRM2_02550	1.82e-309	857.0	COG0173@1|root,COG0173@2|Bacteria,1MUXB@1224|Proteobacteria,42NC6@68525|delta/epsilon subdivisions,2WJEV@28221|Deltaproteobacteria,2MI7X@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
k141_4439_3	155515.JP36_00665	2.18e-79	251.0	COG0530@1|root,COG0530@2|Bacteria,1MU3R@1224|Proteobacteria,1RMRD@1236|Gammaproteobacteria,1Y7QP@135625|Pasteurellales	135625|Pasteurellales	P	Ca2 Na antiporter	Z012_08255	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
k141_384_1	933262.AXAM01000048_gene2581	1.82e-146	423.0	COG0216@1|root,COG0216@2|Bacteria,1MV28@1224|Proteobacteria,42NA3@68525|delta/epsilon subdivisions,2WIQU@28221|Deltaproteobacteria,2MHQM@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
k141_384_2	1121396.KB893072_gene1247	5.7e-35	129.0	COG2890@1|root,COG2890@2|Bacteria,1MXCQ@1224|Proteobacteria,42PKA@68525|delta/epsilon subdivisions,2WNH0@28221|Deltaproteobacteria,2MHVH@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif	prmC	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0032259,GO:0036009,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS,Methyltransf_31
k141_72_1	497321.C664_13809	5.09e-21	92.0	COG1024@1|root,COG1024@2|Bacteria,1R61Y@1224|Proteobacteria,2VM97@28216|Betaproteobacteria,2KYKU@206389|Rhodocyclales	206389|Rhodocyclales	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
k141_72_2	1121405.dsmv_0063	8.72e-152	451.0	COG0045@1|root,COG1042@1|root,COG0045@2|Bacteria,COG1042@2|Bacteria,1MW98@1224|Proteobacteria,42KZW@68525|delta/epsilon subdivisions,2WIQB@28221|Deltaproteobacteria,2MITU@213118|Desulfobacterales	28221|Deltaproteobacteria	C	CoA binding domain	-	-	6.2.1.13	ko:K01905,ko:K22224	ko00010,ko00620,ko00640,ko01100,ko01120,map00010,map00620,map00640,map01100,map01120	-	R00229,R00920	RC00004,RC00012,RC00014	ko00000,ko00001,ko01000,ko01004	-	-	-	ATP-grasp_5,Acetyltransf_3,CoA_binding_2,Succ_CoA_lig
k141_3464_1	1219035.NT2_04_01150	5.12e-16	83.2	COG0642@1|root,COG2205@2|Bacteria,1MUAK@1224|Proteobacteria,2TSUC@28211|Alphaproteobacteria,2JZUS@204457|Sphingomonadales	204457|Sphingomonadales	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
k141_4462_1	387631.Asulf_00238	2.22e-26	107.0	COG2078@1|root,arCOG01336@2157|Archaea,2XUAP@28890|Euryarchaeota,245QD@183980|Archaeoglobi	183980|Archaeoglobi	S	pfam ammecr1	-	-	-	ko:K09141	-	-	-	-	ko00000	-	-	-	AMMECR1
k141_4462_2	96561.Dole_0268	1.12e-104	337.0	COG0760@1|root,COG0760@2|Bacteria,1MWV0@1224|Proteobacteria,42MPK@68525|delta/epsilon subdivisions,2WJM1@28221|Deltaproteobacteria,2MHM6@213118|Desulfobacterales	28221|Deltaproteobacteria	O	PFAM PpiC-type peptidyl-prolyl cis-trans isomerase	nifM	-	5.2.1.8	ko:K03770	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N_3
k141_4585_38	398512.JQKC01000094_gene3355	7.24e-06	48.5	COG4767@1|root,COG4767@2|Bacteria,1VKIA@1239|Firmicutes,24UFZ@186801|Clostridia	186801|Clostridia	V	VanZ like family	-	-	-	-	-	-	-	-	-	-	-	-	VanZ
k141_4585_40	1476973.JMMB01000007_gene231	1.34e-32	115.0	COG0360@1|root,COG0360@2|Bacteria,1VA18@1239|Firmicutes,24QZQ@186801|Clostridia,25RN8@186804|Peptostreptococcaceae	186801|Clostridia	J	Binds together with S18 to 16S ribosomal RNA	rpsF	-	-	ko:K02990	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S6
k141_4585_41	1121324.CLIT_4c02010	1.2e-58	185.0	COG0629@1|root,COG0629@2|Bacteria,1V3WT@1239|Firmicutes,24HF9@186801|Clostridia	186801|Clostridia	L	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism	ssb	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
k141_4585_42	1408823.AXUS01000015_gene1418	1.38e-32	114.0	COG0238@1|root,COG0238@2|Bacteria,1V9XS@1239|Firmicutes,24MQV@186801|Clostridia,25RQP@186804|Peptostreptococcaceae	186801|Clostridia	J	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit	rpsR	-	-	ko:K02963	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S18
k141_4585_43	1121324.CLIT_4c01990	1.3e-23	105.0	COG4241@1|root,COG4241@2|Bacteria,1V8P8@1239|Firmicutes,25CRW@186801|Clostridia	186801|Clostridia	S	Predicted membrane protein (DUF2232)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2232
k141_4585_44	1292035.H476_0036	3.61e-275	776.0	COG3887@1|root,COG3887@2|Bacteria,1TPGP@1239|Firmicutes,2484R@186801|Clostridia,25QFS@186804|Peptostreptococcaceae	186801|Clostridia	T	DHHA1 domain protein	yybT	-	-	-	-	-	-	-	-	-	-	-	DHH,DHHA1
k141_4585_45	500633.CLOHIR_02133	1.84e-51	167.0	COG0359@1|root,COG0359@2|Bacteria,1V6QG@1239|Firmicutes,24MT6@186801|Clostridia,25RF4@186804|Peptostreptococcaceae	186801|Clostridia	J	Binds to the 23S rRNA	rplI	-	-	ko:K02939	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L9_C,Ribosomal_L9_N
k141_4585_46	1286171.EAL2_c22060	3.69e-230	644.0	COG0305@1|root,COG0305@2|Bacteria,1TPCT@1239|Firmicutes,247W3@186801|Clostridia,25VE8@186806|Eubacteriaceae	186801|Clostridia	L	Participates in initiation and elongation during chromosome replication	dnaB	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
k141_4585_47	1089548.KI783301_gene178	3.58e-17	90.1	2EU0H@1|root,33MHJ@2|Bacteria,1VKJD@1239|Firmicutes,4HVWZ@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_4585_49	1238184.CM001792_gene1771	1.1e-09	63.2	COG1670@1|root,COG1670@2|Bacteria,1V1G8@1239|Firmicutes,4HH8Z@91061|Bacilli,23NG3@182709|Oceanobacillus	91061|Bacilli	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
k141_4585_50	768704.Desmer_3566	1.53e-120	359.0	COG3437@1|root,COG3437@2|Bacteria,1UQJH@1239|Firmicutes,248UM@186801|Clostridia,264PV@186807|Peptococcaceae	186801|Clostridia	KT	Response regulator receiver domain	-	-	-	ko:K07814	-	-	-	-	ko00000,ko02022	-	-	-	HD,HD_5,PAS_3,Response_reg
k141_4585_51	929558.SMGD1_2022	8.08e-42	172.0	COG0642@1|root,COG5002@1|root,COG2205@2|Bacteria,COG5002@2|Bacteria,1NRP8@1224|Proteobacteria,42M0Y@68525|delta/epsilon subdivisions,2YNJH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	His Kinase A (phospho-acceptor) domain	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	HATPase_c,HisKA,Hpt,PAS_9,Response_reg
k141_4585_52	1211814.CAPG01000082_gene3825	1.36e-08	60.1	COG4709@1|root,COG4709@2|Bacteria,1VBDQ@1239|Firmicutes,4HM00@91061|Bacilli,1ZFMM@1386|Bacillus	91061|Bacilli	S	Protein of unknown function (DUF1700)	XK27_04830	-	-	-	-	-	-	-	-	-	-	-	DUF1700
k141_4585_55	1286171.EAL2_c21990	4.42e-235	655.0	COG0104@1|root,COG0104@2|Bacteria,1TQ4C@1239|Firmicutes,247RN@186801|Clostridia,25V6G@186806|Eubacteriaceae	186801|Clostridia	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	-	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
k141_4585_61	1211817.CCAT010000009_gene829	5.75e-140	425.0	COG0488@1|root,COG0488@2|Bacteria,1TQNA@1239|Firmicutes,248US@186801|Clostridia,36F40@31979|Clostridiaceae	186801|Clostridia	S	ABC transporter	-	-	-	ko:K18231	ko02010,map02010	-	-	-	br01600,ko00000,ko00001,ko01504,ko02000	3.A.1.121.1,3.A.1.121.3	-	-	ABC_tran,ABC_tran_Xtn
k141_4585_65	1131269.AQVV01000038_gene1561	2.71e-11	73.6	COG0477@1|root,COG2814@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	bacE	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_3
k141_4585_70	536232.CLM_2278	4.33e-05	50.4	COG4767@1|root,COG4767@2|Bacteria,1V3XR@1239|Firmicutes,24JP9@186801|Clostridia,36IJJ@31979|Clostridiaceae	186801|Clostridia	V	VanZ like family	-	-	-	-	-	-	-	-	-	-	-	-	VanZ
k141_4585_71	1347392.CCEZ01000011_gene2454	4.73e-107	323.0	COG1484@1|root,COG1484@2|Bacteria,1TPKM@1239|Firmicutes,2483D@186801|Clostridia,36DQQ@31979|Clostridiaceae	186801|Clostridia	L	DNA replication protein	dnaC	-	-	ko:K02315	-	-	-	-	ko00000,ko03032	-	-	-	IstB_IS21
k141_4585_72	1121324.CLIT_4c01850	1.91e-93	290.0	COG3935@1|root,COG3935@2|Bacteria,1TPR5@1239|Firmicutes,248E7@186801|Clostridia,25R1R@186804|Peptostreptococcaceae	186801|Clostridia	L	Replication initiation and membrane attachment	dnaD	-	-	-	-	-	-	-	-	-	-	-	DnaB_2
k141_4585_73	1121324.CLIT_4c01840	1.91e-147	442.0	COG0739@1|root,COG0739@2|Bacteria,1TRWJ@1239|Firmicutes,24A2J@186801|Clostridia	186801|Clostridia	M	Peptidase, M23	-	-	-	-	-	-	-	-	-	-	-	-	G5,LysM,Peptidase_M23
k141_4585_74	1511.CLOST_2557	1.85e-112	328.0	COG0745@1|root,COG0745@2|Bacteria,1TPQG@1239|Firmicutes,248Z4@186801|Clostridia,25R7G@186804|Peptostreptococcaceae	186801|Clostridia	K	Transcriptional regulatory protein, C terminal	walR	-	-	ko:K07658,ko:K07668	ko02020,map02020	M00434,M00459	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
k141_4585_75	1286171.EAL2_c21910	2.71e-201	583.0	COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,247VG@186801|Clostridia,25UT2@186806|Eubacteriaceae	186801|Clostridia	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein	phoR2	-	2.7.13.3	ko:K07636,ko:K07652	ko02020,map02020	M00434,M00459	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_8,PAS_9
k141_4585_78	1120998.AUFC01000023_gene2186	2.36e-07	58.5	COG4853@1|root,COG4853@2|Bacteria,1VF8C@1239|Firmicutes,24MBB@186801|Clostridia	186801|Clostridia	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	YycI
k141_4200_1	1304885.AUEY01000036_gene2244	8.3e-175	507.0	COG4231@1|root,COG4231@2|Bacteria,1MUKS@1224|Proteobacteria,42N44@68525|delta/epsilon subdivisions,2WIX6@28221|Deltaproteobacteria,2MHSF@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates	iorA	-	1.2.7.8	ko:K00179	-	-	-	-	br01601,ko00000,ko01000	-	-	-	Fer4,POR_N,TPP_enzyme_C
k141_1869_1	298386.PBPRA0461	3.28e-59	202.0	COG1472@1|root,COG1472@2|Bacteria,1MVIV@1224|Proteobacteria,1RMA0@1236|Gammaproteobacteria,1XWNN@135623|Vibrionales	135623|Vibrionales	G	Fibronectin type III-like domain	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
k141_4207_20	1238450.VIBNISOn1_1790033	4.19e-47	155.0	COG0789@1|root,COG0789@2|Bacteria,1RGX6@1224|Proteobacteria,1S8ZG@1236|Gammaproteobacteria,1XXF9@135623|Vibrionales	135623|Vibrionales	K	transcriptional regulators	cueR	-	-	ko:K19591	-	M00769	-	-	ko00000,ko00002,ko01504,ko03000	-	-	-	MerR,MerR-DNA-bind,MerR_1
k141_4207_21	1122207.MUS1_12870	2.64e-315	876.0	COG0272@1|root,COG0272@2|Bacteria,1MV3R@1224|Proteobacteria,1RPAV@1236|Gammaproteobacteria,1XHFN@135619|Oceanospirillales	135619|Oceanospirillales	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	-	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
k141_4207_22	243277.VC_0970	6.91e-99	299.0	COG3115@1|root,COG3115@2|Bacteria,1MVHR@1224|Proteobacteria,1RMDB@1236|Gammaproteobacteria,1XSIV@135623|Vibrionales	135623|Vibrionales	D	Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins	zipA	-	-	ko:K03528	-	-	-	-	ko00000,ko03036	-	-	-	ZipA_C
k141_4207_23	243277.VC_0969	6.66e-112	328.0	COG2981@1|root,COG2981@2|Bacteria,1MVFT@1224|Proteobacteria,1RMQT@1236|Gammaproteobacteria,1XTRY@135623|Vibrionales	135623|Vibrionales	U	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway	cysZ	GO:0003674,GO:0005215	-	ko:K06203	-	-	-	-	ko00000	-	-	-	EI24
k141_4207_24	29495.EA26_04795	5.99e-190	532.0	COG0031@1|root,COG0031@2|Bacteria,1MUBE@1224|Proteobacteria,1RN6J@1236|Gammaproteobacteria,1XTGD@135623|Vibrionales	135623|Vibrionales	E	Belongs to the cysteine synthase cystathionine beta- synthase family	cysK	-	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
k141_4586_1	243277.VC_0711	0.0	1475.0	COG0542@1|root,COG0542@2|Bacteria,1MURH@1224|Proteobacteria,1RN55@1236|Gammaproteobacteria,1XSEU@135623|Vibrionales	135623|Vibrionales	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	GO:0003674,GO:0003824,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:0140096,GO:1901564	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
k141_4586_2	675814.VIC_000494	6.75e-103	305.0	COG1496@1|root,COG1496@2|Bacteria,1MW2H@1224|Proteobacteria,1RNV4@1236|Gammaproteobacteria,1XSY8@135623|Vibrionales	135623|Vibrionales	S	Belongs to the multicopper oxidase YfiH RL5 family	yfiH	-	-	ko:K05810	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase_4
k141_4586_3	1219065.VPR01S_09_00030	4.99e-195	545.0	COG0564@1|root,COG0564@2|Bacteria,1MUBN@1224|Proteobacteria,1RN7F@1236|Gammaproteobacteria,1XSYP@135623|Vibrionales	135623|Vibrionales	J	Responsible for synthesis of pseudouridine from uracil	rluD	GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
k141_4586_4	29495.EA26_03640	2.17e-120	349.0	COG4105@1|root,COG4105@2|Bacteria,1MVS5@1224|Proteobacteria,1RSE6@1236|Gammaproteobacteria,1XSWB@135623|Vibrionales	135623|Vibrionales	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamD	GO:0005575,GO:0005623,GO:0008104,GO:0008150,GO:0009279,GO:0009987,GO:0016020,GO:0016043,GO:0019867,GO:0030312,GO:0030313,GO:0031224,GO:0031230,GO:0031241,GO:0031246,GO:0031975,GO:0032991,GO:0033036,GO:0034613,GO:0043163,GO:0044425,GO:0044462,GO:0044464,GO:0045184,GO:0045229,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0061024,GO:0070727,GO:0071840,GO:0071944,GO:0072657,GO:0090150,GO:0098552,GO:0098796,GO:1990063	-	ko:K05807	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	YfiO
k141_4586_5	243277.VC_0706	2.14e-56	177.0	COG1544@1|root,COG1544@2|Bacteria,1RD2Y@1224|Proteobacteria,1S6GT@1236|Gammaproteobacteria,1XXCP@135623|Vibrionales	135623|Vibrionales	J	COG1544 Ribosome-associated protein Y (PSrp-1)	raiA	-	-	ko:K05809	-	-	-	-	ko00000,ko03009	-	-	-	Ribosomal_S30AE
k141_4586_6	345073.VC395_0722	8.56e-213	595.0	COG0077@1|root,COG1605@1|root,COG0077@2|Bacteria,COG1605@2|Bacteria,1MU60@1224|Proteobacteria,1RNRD@1236|Gammaproteobacteria,1XT8C@135623|Vibrionales	135623|Vibrionales	E	chorismate mutase	pheA	-	4.2.1.51,5.4.99.5	ko:K14170	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R00691,R01373,R01715	RC00360,RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	CM_2,PDT
k141_4586_7	1348635.BBJY01000008_gene1701	3.05e-138	403.0	COG0687@1|root,COG0687@2|Bacteria,1R45E@1224|Proteobacteria,1RPF9@1236|Gammaproteobacteria,1XV8Q@135623|Vibrionales	135623|Vibrionales	E	COG0687 Spermidine putrescine-binding periplasmic protein	-	GO:0003674,GO:0003824,GO:0005215,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0015203,GO:0015399,GO:0015405,GO:0015417,GO:0015695,GO:0015696,GO:0015846,GO:0015847,GO:0015848,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0042623,GO:0042626,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:1902047	-	ko:K11069	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	SBP_bac_8
k141_4586_8	675815.VOA_003149	0.0	1030.0	COG5001@1|root,COG5001@2|Bacteria,1PRV9@1224|Proteobacteria,1RZHM@1236|Gammaproteobacteria,1XSCI@135623|Vibrionales	135623|Vibrionales	T	COG2199 FOG GGDEF domain	mbaA	GO:0007154,GO:0007165,GO:0008150,GO:0009987,GO:0023052,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007	3.1.4.52	ko:K20966	ko05111,map05111	-	-	-	ko00000,ko00001,ko01000	-	-	-	EAL,GGDEF
k141_4586_9	1051646.VITU9109_14778	2.79e-84	253.0	COG1986@1|root,COG1986@2|Bacteria,1RG2E@1224|Proteobacteria,1S5QG@1236|Gammaproteobacteria,1XUT8@135623|Vibrionales	135623|Vibrionales	F	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions	yjjX	GO:0003674,GO:0003824,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111	-	-	-	-	-	-	-	-	-	-	NTPase_I-T
k141_4586_10	243277.VC_0701	1.25e-36	127.0	COG2973@1|root,COG2973@2|Bacteria,1MYB2@1224|Proteobacteria,1S6RH@1236|Gammaproteobacteria,1XYA5@135623|Vibrionales	135623|Vibrionales	K	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon and prevents the initiation of transcription	trpR	GO:0003674,GO:0003700,GO:0006082,GO:0006355,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009072,GO:0009308,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0019752,GO:0031323,GO:0031326,GO:0034641,GO:0042430,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0140110,GO:1901360,GO:1901564,GO:1901605,GO:1903506,GO:2000112,GO:2001141	-	ko:K03720	-	-	-	-	ko00000,ko03000	-	-	-	Trp_repressor
k141_4586_11	675815.VOA_003152	1.21e-197	578.0	COG0741@1|root,COG0741@2|Bacteria,1MV3F@1224|Proteobacteria,1RMS8@1236|Gammaproteobacteria,1XUVC@135623|Vibrionales	135623|Vibrionales	M	COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)	slt	-	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	SLT,SLT_L
k141_4586_13	243277.VC_0697	1.02e-42	144.0	2E3XG@1|root,32YUI@2|Bacteria,1N8RF@1224|Proteobacteria,1SCJ3@1236|Gammaproteobacteria,1XYEY@135623|Vibrionales	135623|Vibrionales	S	Binds the second messenger bis-(3'-5') cyclic dimeric guanosine monophosphate (c-di-GMP). Can bind two c-di-GMP molecules per monomer. May play a role in bacterial second- messenger regulated processes. Binding to c-di-GMP induces a conformational change of the C- and N-termini resulting in the exposure of a highly negative surface on one side of the protein to a	-	-	-	-	-	-	-	-	-	-	-	-	PilZ
k141_4586_14	1348635.BBJY01000008_gene1708	1.61e-217	606.0	COG0287@1|root,COG1605@1|root,COG0287@2|Bacteria,COG1605@2|Bacteria,1MVUT@1224|Proteobacteria,1RQB3@1236|Gammaproteobacteria,1XUE1@135623|Vibrionales	135623|Vibrionales	E	T-protein	tyrA	-	1.3.1.12,5.4.99.5	ko:K14187	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00024,M00025	R01715,R01728	RC00125,RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	CM_2,PDH
k141_4586_15	870967.VIS19158_01679	5.82e-208	580.0	COG0722@1|root,COG0722@2|Bacteria,1MU5Q@1224|Proteobacteria,1RMAA@1236|Gammaproteobacteria,1XSXX@135623|Vibrionales	135623|Vibrionales	E	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)	aroF	-	2.5.1.54	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_1
k141_4586_16	675806.VII_003056	1.24e-292	811.0	COG3275@1|root,COG3275@2|Bacteria,1QUB1@1224|Proteobacteria,1T1RX@1236|Gammaproteobacteria,1XU1C@135623|Vibrionales	135623|Vibrionales	T	regulator of cell autolysis	yehU	-	2.7.13.3	ko:K02478	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	5TM-5TMR_LYT,GAF_3,His_kinase,SpoVT_C
k141_4586_17	55601.VANGNB10_cI0619c	6.3e-107	315.0	COG3279@1|root,COG3279@2|Bacteria,1MUE8@1224|Proteobacteria,1RMJJ@1236|Gammaproteobacteria,1XU8Z@135623|Vibrionales	135623|Vibrionales	K	COG3279 Response regulator of the LytR AlgR family	yehT	GO:0000156,GO:0000160,GO:0003674,GO:0007154,GO:0007165,GO:0008150,GO:0009987,GO:0023052,GO:0035556,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0060089,GO:0065007	-	ko:K02477	-	-	-	-	ko00000,ko02022	-	-	-	LytTR,Response_reg
k141_4586_18	870967.VIS19158_01659	1.08e-161	461.0	COG1472@1|root,COG1472@2|Bacteria,1MVAJ@1224|Proteobacteria,1RMQF@1236|Gammaproteobacteria,1XU7E@135623|Vibrionales	135623|Vibrionales	G	Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides	nagZ	GO:0000270,GO:0003674,GO:0003824,GO:0004553,GO:0004563,GO:0006022,GO:0006807,GO:0008150,GO:0008152,GO:0009254,GO:0009273,GO:0009987,GO:0015929,GO:0016787,GO:0016798,GO:0030203,GO:0042546,GO:0043170,GO:0044085,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901564	3.2.1.52	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	M00628	R00022,R05963,R07809,R07810,R10831	RC00049	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyco_hydro_3
k141_4586_19	1219077.VAZ01S_045_00390	6.59e-148	429.0	COG2377@1|root,COG2377@2|Bacteria,1MV4E@1224|Proteobacteria,1RNTZ@1236|Gammaproteobacteria,1XTEE@135623|Vibrionales	135623|Vibrionales	F	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling	anmK	-	2.7.1.170	ko:K09001	-	-	-	-	ko00000,ko01000	-	-	-	AnmK
k141_4586_20	55601.VANGNB10_cI0616c	2.17e-156	446.0	COG2103@1|root,COG2103@2|Bacteria,1MVDR@1224|Proteobacteria,1RN3P@1236|Gammaproteobacteria,1XUH3@135623|Vibrionales	135623|Vibrionales	S	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate. Together with AnmK, is also required for the utilization of anhydro-N-acetylmuramic acid (anhMurNAc) either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling	murQ	-	4.2.1.126	ko:K07106	ko00520,ko01100,map00520,map01100	-	R08555	RC00397,RC00746	ko00000,ko00001,ko01000	-	-	-	SIS,SIS_2
k141_4586_21	675816.VIA_000360	4.33e-46	151.0	2ED5M@1|root,3372C@2|Bacteria,1N2Z7@1224|Proteobacteria,1SEVD@1236|Gammaproteobacteria,1XY03@135623|Vibrionales	135623|Vibrionales	S	Protein of unknown function (DUF2799)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2799
k141_4586_22	945550.VISI1226_18026	5.62e-283	782.0	COG1966@1|root,COG1966@2|Bacteria,1MWF9@1224|Proteobacteria,1RMG4@1236|Gammaproteobacteria,1XSKR@135623|Vibrionales	135623|Vibrionales	T	Carbon starvation protein	cstA	-	-	-	-	-	-	-	-	-	-	-	CstA,CstA_5TM
k141_4586_23	223926.28805520	7.9e-179	504.0	COG0761@1|root,COG0761@2|Bacteria,1MU7G@1224|Proteobacteria,1RMN8@1236|Gammaproteobacteria,1XTYD@135623|Vibrionales	135623|Vibrionales	IM	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis	ispH	-	1.17.7.4	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05884,R08210	RC01137,RC01487	ko00000,ko00001,ko00002,ko01000	-	-	-	LYTB
k141_4586_24	675814.VIC_000522	7.19e-90	266.0	COG0597@1|root,COG0597@2|Bacteria,1RGV9@1224|Proteobacteria,1S60E@1236|Gammaproteobacteria,1XT9S@135623|Vibrionales	135623|Vibrionales	MU	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	lspA	-	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
k141_4586_26	1348635.BBJY01000008_gene1722	3.94e-176	496.0	COG0196@1|root,COG0196@2|Bacteria,1MV9I@1224|Proteobacteria,1RN44@1236|Gammaproteobacteria,1XTHQ@135623|Vibrionales	135623|Vibrionales	H	Belongs to the ribF family	ribF	-	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
k141_4586_29	1051646.VITU9109_21509	2.44e-47	153.0	COG0640@1|root,COG0640@2|Bacteria,1N72Q@1224|Proteobacteria,1SCH5@1236|Gammaproteobacteria,1XXWQ@135623|Vibrionales	135623|Vibrionales	K	transcriptional regulators	hlyU	GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044212,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:2000112,GO:2001141	-	ko:K22042	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5
k141_2193_1	1121930.AQXG01000007_gene490	0.0009	51.2	COG1649@1|root,COG4254@1|root,COG4733@1|root,COG1649@2|Bacteria,COG4254@2|Bacteria,COG4733@2|Bacteria,4NT4E@976|Bacteroidetes,1IU8A@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM FecR protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_5190_2	555779.Dthio_PD2774	2.85e-77	238.0	COG1830@1|root,COG1830@2|Bacteria,1MWJW@1224|Proteobacteria,42NP9@68525|delta/epsilon subdivisions,2WIP9@28221|Deltaproteobacteria,2M85K@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	Catalyzes a transaldol reaction between 6-deoxy-5- ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2- amino-3,7-dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids	aroA'	-	4.1.2.13	ko:K11645	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	DeoC
k141_2194_1	1265505.ATUG01000002_gene1425	8.74e-31	122.0	28MK7@1|root,2ZAWI@2|Bacteria,1R83K@1224|Proteobacteria,42MZ5@68525|delta/epsilon subdivisions,2WKYR@28221|Deltaproteobacteria,2MISC@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_2833_2	243277.VC_0165	3.34e-161	463.0	COG0845@1|root,COG0845@2|Bacteria,1MUFW@1224|Proteobacteria,1RQJ9@1236|Gammaproteobacteria,1XT7F@135623|Vibrionales	135623|Vibrionales	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	HlyD_D23
k141_2833_3	1280001.BAOA01000051_gene1603	0.0	1482.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,1XSSQ@135623|Vibrionales	135623|Vibrionales	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K18138	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
k141_2833_4	55601.VANGNB10_cI2641	2.82e-34	119.0	COG2960@1|root,COG2960@2|Bacteria,1N7AH@1224|Proteobacteria,1SCH1@1236|Gammaproteobacteria,1XYA8@135623|Vibrionales	135623|Vibrionales	S	protein conserved in bacteria	yqiC	-	-	ko:K09806	-	-	-	-	ko00000	-	-	-	BMFP
k141_2833_6	243277.VC_0161	7.13e-154	439.0	COG0583@1|root,COG0583@2|Bacteria,1MZX1@1224|Proteobacteria,1RNFR@1236|Gammaproteobacteria,1XSJR@135623|Vibrionales	135623|Vibrionales	K	Transcriptional regulator	ilvY	-	-	ko:K02521	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,LysR_substrate
k141_243_1	1280001.BAOA01000136_gene1934	2.63e-132	377.0	COG0302@1|root,COG0302@2|Bacteria,1MY3N@1224|Proteobacteria,1RMQM@1236|Gammaproteobacteria,1XUKF@135623|Vibrionales	135623|Vibrionales	F	GTP cyclohydrolase	folE	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006082,GO:0006575,GO:0006725,GO:0006729,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0019752,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0043603,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	3.5.4.16	ko:K01495	ko00790,ko01100,map00790,map01100	M00126,M00841,M00842,M00843	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_cyclohydroI
k141_243_2	595494.Tola_1535	5.93e-277	764.0	COG0531@1|root,COG0531@2|Bacteria,1MXNJ@1224|Proteobacteria,1RQCJ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	amino acid	eat	-	-	ko:K16238	-	-	-	-	ko00000,ko02000	2.A.3.5	-	-	AA_permease_2
k141_243_3	357804.Ping_0277	1.01e-140	404.0	COG4302@1|root,COG4302@2|Bacteria,1MWQI@1224|Proteobacteria,1RQ2T@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Belongs to the EutC family	eutC	-	4.3.1.7	ko:K03736	ko00564,ko01100,map00564,map01100	-	R00749	RC00370	ko00000,ko00001,ko01000	-	-	-	EutC
k141_243_4	357804.Ping_0276	3.67e-182	516.0	COG4303@1|root,COG4303@2|Bacteria,1MUR4@1224|Proteobacteria,1RPN8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	With EutC catalyzes the formation of acetaldehyde and ammonia from ethanolamine	eutB	-	4.3.1.7	ko:K03735	ko00564,ko01100,map00564,map01100	-	R00749	RC00370	ko00000,ko00001,ko01000	-	-	-	EutB
k141_4588_1	1124983.PFLCHA0_c25540	3.5e-18	84.0	COG0477@1|root,COG2814@2|Bacteria,1QTY0@1224|Proteobacteria,1T378@1236|Gammaproteobacteria,1YTET@136843|Pseudomonas fluorescens group	1236|Gammaproteobacteria	EGP	Major Facilitator Superfamily	emrB	-	-	ko:K03446	-	M00701	-	-	ko00000,ko00002,ko02000	2.A.1.3	-	-	MFS_1,Sugar_tr
k141_1892_3	1283284.AZUK01000001_gene271	1.47e-195	559.0	COG1538@1|root,COG1538@2|Bacteria,1MUZZ@1224|Proteobacteria,1RQEP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	MU	RND efflux system, outer membrane lipoprotein	mdtP	-	-	-	-	-	-	-	-	-	-	-	OEP
k141_1892_5	1348635.BBJY01000005_gene3363	5.25e-46	155.0	COG1484@1|root,COG1484@2|Bacteria,1MZNW@1224|Proteobacteria,1RQFW@1236|Gammaproteobacteria,1XYUP@135623|Vibrionales	135623|Vibrionales	L	IstB-like ATP binding protein	-	-	-	-	-	-	-	-	-	-	-	-	IstB_IS21
k141_2834_1	272623.L174523	4.17e-22	100.0	COG1307@1|root,COG1461@1|root,COG1307@2|Bacteria,COG1461@2|Bacteria,1TR6J@1239|Firmicutes,4HC2T@91061|Bacilli,1YC1T@1357|Lactococcus	91061|Bacilli	S	Dak2	yfhG	-	-	ko:K07030	-	-	-	-	ko00000	-	-	-	Dak2,DegV
k141_3223_1	177437.HRM2_26670	1.71e-300	845.0	COG0542@1|root,COG0542@2|Bacteria,1MV8B@1224|Proteobacteria,42M2T@68525|delta/epsilon subdivisions,2WJ2W@28221|Deltaproteobacteria,2MHMB@213118|Desulfobacterales	28221|Deltaproteobacteria	O	ATP-dependent Clp protease ATP-binding subunit ClpA	clpA	-	-	ko:K03694	-	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
k141_3223_2	1123248.KB893323_gene1622	2.31e-62	198.0	COG2360@1|root,COG2360@2|Bacteria,4NG3A@976|Bacteroidetes,1IP1V@117747|Sphingobacteriia	976|Bacteroidetes	O	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine	aat	-	2.3.2.6	ko:K00684	-	-	R03813,R11443,R11444	RC00055,RC00064	ko00000,ko01000	-	-	-	Leu_Phe_trans
k141_2195_1	269799.Gmet_3081	1.96e-91	280.0	COG2801@1|root,COG2801@2|Bacteria,1NUYG@1224|Proteobacteria,42ZK0@68525|delta/epsilon subdivisions,2WUUJ@28221|Deltaproteobacteria,43URT@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	Homeodomain-like domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_23,rve
k141_1893_1	1454202.PPBDW_10016___1	1.21e-20	89.7	COG0666@1|root,COG0666@2|Bacteria,1NMUY@1224|Proteobacteria	1224|Proteobacteria	S	Ankyrin repeat	-	-	-	-	-	-	-	-	-	-	-	-	Ank_2,Ank_3,Ank_4
k141_1625_20	1121289.JHVL01000007_gene2804	3.33e-203	566.0	COG0451@1|root,COG0451@2|Bacteria,1VP6I@1239|Firmicutes,251A8@186801|Clostridia,36UJ5@31979|Clostridiaceae	186801|Clostridia	M	NAD-dependent epimerase dehydratase	-	-	4.2.1.45,4.2.1.46	ko:K01709,ko:K01710	ko00520,ko00521,ko00523,ko00525,ko01055,ko01130,map00520,map00521,map00523,map00525,map01055,map01130	M00793	R02426,R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
k141_1625_21	203119.Cthe_2644	2.87e-198	558.0	COG0399@1|root,COG0399@2|Bacteria,1TPDH@1239|Firmicutes,24862@186801|Clostridia,3WI7G@541000|Ruminococcaceae	186801|Clostridia	E	Belongs to the DegT DnrJ EryC1 family	-	-	2.6.1.102	ko:K13010	ko00520,map00520	-	R10460	RC00006,RC00781	ko00000,ko00001,ko01000,ko01005,ko01007	-	-	-	DegT_DnrJ_EryC1
k141_1625_22	1511.CLOST_0365	3.48e-193	542.0	COG0517@1|root,COG1208@1|root,COG0517@2|Bacteria,COG1208@2|Bacteria,1TRKP@1239|Firmicutes,248ZS@186801|Clostridia,25SUJ@186804|Peptostreptococcaceae	186801|Clostridia	JM	Nucleotidyl transferase	-	-	2.7.7.71	ko:K15669	ko00540,map00540	-	R09772	RC00002	ko00000,ko00001,ko01000	-	-	-	CBS,NTP_transferase
k141_1625_23	1242969.ATCC51562_1146	1.9e-134	389.0	COG0223@1|root,COG0223@2|Bacteria,1RAVE@1224|Proteobacteria,42NQD@68525|delta/epsilon subdivisions,2YNGG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Formyl transferase	-	-	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
k141_1625_24	203119.Cthe_2641	8.77e-155	444.0	COG2089@1|root,COG2089@2|Bacteria,1TS09@1239|Firmicutes,249DN@186801|Clostridia,3WHC1@541000|Ruminococcaceae	186801|Clostridia	M	N-acetylneuraminate synthase	neuB	-	2.5.1.101,2.5.1.56	ko:K01654,ko:K18430	ko00520,ko01100,map00520,map01100	-	R01804,R04435,R10304	RC00159	ko00000,ko00001,ko01000	-	-	-	NeuB,SAF
k141_1625_25	796940.HMPREF9628_00643	6.74e-172	492.0	COG0381@1|root,COG0381@2|Bacteria,1TQKQ@1239|Firmicutes,24A0H@186801|Clostridia,25T09@186804|Peptostreptococcaceae	186801|Clostridia	M	UDP-N-acetylglucosamine 2-epimerase	neuC	-	3.2.1.184,5.1.3.14	ko:K01791,ko:K18429	ko00520,ko01100,ko05111,map00520,map01100,map05111	M00362	R00420,R10187	RC00005,RC00288,RC00290	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase_2
k141_1625_26	871963.Desdi_3207	3.93e-131	383.0	COG0673@1|root,COG0673@2|Bacteria,1UTD8@1239|Firmicutes,24CI2@186801|Clostridia	186801|Clostridia	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
k141_1625_27	871963.Desdi_3206	1.83e-117	348.0	COG0673@1|root,COG0673@2|Bacteria,1UP62@1239|Firmicutes,24B2A@186801|Clostridia	186801|Clostridia	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
k141_1625_28	397288.C806_02761	5.79e-11	68.6	COG1083@1|root,COG1083@2|Bacteria,1UFAT@1239|Firmicutes,24G5I@186801|Clostridia,27JRG@186928|unclassified Lachnospiraceae	186801|Clostridia	M	Cytidylyltransferase	neuA	-	2.7.7.82	ko:K18431	ko00520,map00520	-	R10182	RC00152	ko00000,ko00001,ko01000	-	-	-	CTP_transf_3
k141_1625_29	1292035.H476_0069	2.25e-213	597.0	COG0192@1|root,COG0192@2|Bacteria,1TPCV@1239|Firmicutes,248QF@186801|Clostridia,25QJU@186804|Peptostreptococcaceae	186801|Clostridia	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	-	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
k141_1625_30	140626.JHWB01000009_gene1210	3.88e-34	131.0	COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia	186801|Clostridia	N	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella	-	-	-	ko:K02406	ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flagellin_C,Flagellin_N
k141_1625_31	1391646.AVSU01000017_gene3118	7.2e-313	878.0	COG0272@1|root,COG0507@1|root,COG0272@2|Bacteria,COG0507@2|Bacteria,1TPZH@1239|Firmicutes,247R7@186801|Clostridia,25QNC@186804|Peptostreptococcaceae	186801|Clostridia	L	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity	recD2	-	3.1.11.5	ko:K03581	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AAA_30,HHH_4,HHH_5,UvrD_C_2
k141_1625_32	1408823.AXUS01000007_gene3028	4.32e-42	151.0	COG1040@1|root,COG1040@2|Bacteria,1VF2G@1239|Firmicutes,24IG6@186801|Clostridia,25RF0@186804|Peptostreptococcaceae	186801|Clostridia	S	ComF family	comF	-	-	ko:K02242	-	M00429	-	-	ko00000,ko00002,ko02044	-	-	-	Pribosyltran
k141_1625_33	1511.CLOST_2353	3.7e-45	150.0	2D61I@1|root,32TKA@2|Bacteria,1VB5H@1239|Firmicutes,24NZW@186801|Clostridia,25U2C@186804|Peptostreptococcaceae	186801|Clostridia	N	TIGRFAM flagellar operon protein	yvyF	-	-	-	-	-	-	-	-	-	-	-	-
k141_1625_34	1304284.L21TH_2577	3.16e-08	53.9	COG2747@1|root,COG2747@2|Bacteria,1VKDG@1239|Firmicutes,24UWF@186801|Clostridia,36NY8@31979|Clostridiaceae	186801|Clostridia	KNU	Anti-sigma-28 factor, FlgM	-	-	-	ko:K02398	ko02020,ko02025,ko02026,ko02040,map02020,map02025,map02026,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FlgM
k141_1625_35	1286171.EAL2_c03150	3.81e-35	127.0	29GQE@1|root,32MNN@2|Bacteria,1VQ2C@1239|Firmicutes	1239|Firmicutes	S	FlgN protein	-	-	-	-	-	-	-	-	-	-	-	-	FlgN
k141_1625_36	1121324.CLIT_13c00780	2.21e-144	435.0	COG1256@1|root,COG1256@2|Bacteria,1TPXH@1239|Firmicutes,249PE@186801|Clostridia	186801|Clostridia	N	TIGRFAM Flagellar hook-associated protein, FlgK	flgK	-	-	ko:K02396	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod,Flg_bbr_C
k141_1625_37	1120972.AUMH01000031_gene997	5.57e-16	87.0	COG1344@1|root,COG1344@2|Bacteria,1TPDT@1239|Firmicutes,4HCCZ@91061|Bacilli,278AV@186823|Alicyclobacillaceae	91061|Bacilli	N	Belongs to the bacterial flagellin family	flgL	GO:0005575,GO:0005576,GO:0005623,GO:0009288,GO:0042995,GO:0043226,GO:0043228,GO:0044464	-	ko:K02397	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flagellin_C,Flagellin_N
k141_2638_1	1121324.CLIT_4c00300	4.49e-147	427.0	COG0240@1|root,COG0240@2|Bacteria,1TUSI@1239|Firmicutes,249QW@186801|Clostridia,25TGI@186804|Peptostreptococcaceae	186801|Clostridia	C	NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain	odh	-	1.5.1.28	ko:K04940	-	-	-	-	ko00000,ko01000	-	-	-	ApbA,NAD_Gly3P_dh_N,Octopine_DH
k141_2638_3	1230342.CTM_10983	7.23e-108	343.0	COG5001@1|root,COG5001@2|Bacteria,1TP8V@1239|Firmicutes,247PX@186801|Clostridia,36E1W@31979|Clostridiaceae	186801|Clostridia	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	ABC_sub_bind,EAL,GGDEF,PAS_3,PAS_9,PocR
k141_2638_4	865861.AZSU01000006_gene1386	7.44e-41	167.0	COG5001@1|root,COG5001@2|Bacteria,1TP8V@1239|Firmicutes,247PX@186801|Clostridia,36E1W@31979|Clostridiaceae	186801|Clostridia	T	Diguanylate cyclase	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	EAL,GGDEF,PAS_9,SBP_bac_3
k141_2638_5	1321778.HMPREF1982_01868	5.39e-205	580.0	COG0124@1|root,COG0124@2|Bacteria,1TP3D@1239|Firmicutes,24852@186801|Clostridia,268DU@186813|unclassified Clostridiales	186801|Clostridia	J	Psort location Cytoplasmic, score 10.00	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
k141_2638_6	1443122.Z958_08455	2.09e-179	525.0	COG0076@1|root,COG0076@2|Bacteria,1TRVW@1239|Firmicutes,25D2Y@186801|Clostridia,36GDE@31979|Clostridiaceae	186801|Clostridia	E	Pyridoxal-dependent decarboxylase conserved domain	-	-	-	-	-	-	-	-	-	-	-	-	Pyridoxal_deC
k141_2638_7	1307761.L21SP2_1997	2.26e-10	63.2	COG1863@1|root,COG1863@2|Bacteria,2J884@203691|Spirochaetes	203691|Spirochaetes	P	Na+/H+ ion antiporter subunit	-	-	-	ko:K05569	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	MNHE
k141_2638_8	1286171.EAL2_c20680	1.75e-05	45.1	COG2212@1|root,COG2212@2|Bacteria,1VH97@1239|Firmicutes,24T3T@186801|Clostridia	186801|Clostridia	P	Multiple resistance and pH regulation protein F (MrpF / PhaF)	-	-	-	ko:K05570	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	MrpF_PhaF
k141_2638_9	293826.Amet_4157	2.54e-05	46.6	COG1320@1|root,COG1320@2|Bacteria,1VHQ3@1239|Firmicutes,24RQT@186801|Clostridia,36KTJ@31979|Clostridiaceae	186801|Clostridia	P	Na+/H+ antiporter subunit	-	-	-	ko:K05571	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	PhaG_MnhG_YufB
k141_2638_10	1499967.BAYZ01000028_gene1300	2.19e-09	58.5	COG1563@1|root,COG1563@2|Bacteria,2NRSK@2323|unclassified Bacteria	2|Bacteria	P	Domain of unknown function (DUF4040)	mnhB	-	-	ko:K05566	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	DUF4040,MnhB
k141_2638_11	1304284.L21TH_0053	8.57e-11	60.1	COG2111@1|root,COG2111@2|Bacteria,1VPIK@1239|Firmicutes,24VEZ@186801|Clostridia	186801|Clostridia	P	Na H antiporter	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_2638_12	318167.Sfri_2284	5.01e-05	48.9	COG2111@1|root,COG2111@2|Bacteria,1N1CK@1224|Proteobacteria,1RR3K@1236|Gammaproteobacteria,2Q9B0@267890|Shewanellaceae	1236|Gammaproteobacteria	P	PFAM Na H antiporter MnhB subunit-related protein	-	-	-	ko:K05566	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	DUF4040,MnhB
k141_2638_13	1499967.BAYZ01000028_gene1295	1.97e-17	78.6	COG1006@1|root,COG1006@2|Bacteria,2NQ57@2323|unclassified Bacteria	2|Bacteria	P	NADH-ubiquinone/plastoquinone oxidoreductase chain 4L	-	-	-	ko:K05567	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	Oxidored_q2
k141_2638_14	1229520.ADIAL_2091	5.73e-34	142.0	COG0651@1|root,COG0651@2|Bacteria,1TRAT@1239|Firmicutes,4HA10@91061|Bacilli,27FAQ@186828|Carnobacteriaceae	91061|Bacilli	CP	Proton-conducting membrane transporter	mrpD	GO:0003674,GO:0005215,GO:0005451,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008150,GO:0008324,GO:0015075,GO:0015077,GO:0015078,GO:0015081,GO:0015291,GO:0015297,GO:0015298,GO:0015299,GO:0015318,GO:0015385,GO:0015491,GO:0015672,GO:0022804,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0035725,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0098655,GO:0098660,GO:0098662,GO:0099516,GO:1902600	-	ko:K05568	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	iSB619.SA_RS04615	Proton_antipo_M
k141_2638_15	350688.Clos_0240	1.71e-82	251.0	COG3859@1|root,COG3859@2|Bacteria,1V1WX@1239|Firmicutes,24E4Z@186801|Clostridia,36IVJ@31979|Clostridiaceae	186801|Clostridia	S	Proton-coupled thiamine transporter YuaJ	yuaJ	-	-	ko:K16789	-	-	-	-	ko00000,ko02000	2.A.88.3	-	-	Thia_YuaJ
k141_2638_16	1280673.AUJJ01000005_gene328	2.32e-21	103.0	COG3437@1|root,COG3437@2|Bacteria,1UX7W@1239|Firmicutes,25P74@186801|Clostridia,4BXGG@830|Butyrivibrio	186801|Clostridia	T	Histidine Phosphotransfer domain	-	-	-	-	-	-	-	-	-	-	-	-	HD,HisKA,Hpt,Response_reg
k141_2638_17	1031288.AXAA01000010_gene454	2.14e-20	103.0	COG0840@1|root,COG0840@2|Bacteria,1URS2@1239|Firmicutes,24B7E@186801|Clostridia,36H9N@31979|Clostridiaceae	186801|Clostridia	NT	histidine kinase HAMP region domain protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal
k141_2638_18	1121289.JHVL01000026_gene190	5.16e-115	331.0	COG1592@1|root,COG1592@2|Bacteria,1TSUY@1239|Firmicutes,248GY@186801|Clostridia,36EFS@31979|Clostridiaceae	186801|Clostridia	C	Rubrerythrin	rbr3A	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
k141_2638_19	1319815.HMPREF0202_00334	1.73e-73	228.0	COG0778@1|root,COG0778@2|Bacteria	2|Bacteria	C	coenzyme F420-1:gamma-L-glutamate ligase activity	ydfN	-	-	ko:K15976	-	-	-	-	ko00000,ko01000	-	-	-	Nitroreductase
k141_2638_20	1444310.JANV01000095_gene3186	1.49e-07	62.4	COG1376@1|root,COG3409@1|root,COG1376@2|Bacteria,COG3409@2|Bacteria,1V6J2@1239|Firmicutes,4HJZH@91061|Bacilli,1ZBKG@1386|Bacillus	91061|Bacilli	O	ErfK YbiS YcfS YnhG family protein	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_1,YkuD
k141_2638_22	398767.Glov_0393	4.21e-09	66.6	COG0845@1|root,COG0845@2|Bacteria,1MU8D@1224|Proteobacteria,42NVA@68525|delta/epsilon subdivisions,2WN7Z@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K13888	-	M00709	-	-	ko00000,ko00002,ko02000	8.A.1	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
k141_2638_23	1499684.CCNP01000021_gene2876	5.47e-66	222.0	COG0577@1|root,COG0577@2|Bacteria,1TPUU@1239|Firmicutes,24AWU@186801|Clostridia,36FYR@31979|Clostridiaceae	186801|Clostridia	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
k141_2638_24	220664.PFL_4082	9.31e-63	214.0	COG0577@1|root,COG1136@1|root,COG0577@2|Bacteria,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,1RNUJ@1236|Gammaproteobacteria,1YMKR@136843|Pseudomonas fluorescens group	1236|Gammaproteobacteria	V	Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides	macB	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0015893,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0042221,GO:0042493,GO:0042891,GO:0044425,GO:0044459,GO:0044464,GO:0046677,GO:0050896,GO:0051179,GO:0051234,GO:0071944	-	ko:K05685	ko02010,map02010	M00709	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.122.1,3.A.1.122.12	-	-	ABC_tran,FtsX,MacB_PCD
k141_2638_25	86416.Clopa_4590	0.000122	53.9	COG2770@1|root,COG5002@1|root,COG2770@2|Bacteria,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,247VG@186801|Clostridia,36F2H@31979|Clostridiaceae	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
k141_2638_26	1463858.JOHR01000006_gene373	1.15e-27	117.0	COG0491@1|root,COG0491@2|Bacteria,2HFVZ@201174|Actinobacteria	201174|Actinobacteria	Q	beta-lactamase domain protein	-	-	-	ko:K05555	ko01057,ko01130,map01057,map01130	M00778	R09305	-	ko00000,ko00001,ko00002,ko01000,ko01008	-	-	-	Lactamase_B
k141_2638_27	273068.TTE1202	1.05e-44	169.0	COG3290@1|root,COG3290@2|Bacteria,1TQNZ@1239|Firmicutes,249FI@186801|Clostridia	186801|Clostridia	T	Histidine kinase-like ATPases	-	-	2.7.13.3	ko:K07717	ko02020,map02020	M00518	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c
k141_2638_28	37659.JNLN01000001_gene499	8.24e-57	191.0	COG4753@1|root,COG4753@2|Bacteria,1TPFP@1239|Firmicutes,24AIA@186801|Clostridia,36G5B@31979|Clostridiaceae	186801|Clostridia	T	YcbB domain	-	-	-	ko:K07719	ko02020,map02020	M00518	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,YcbB
k141_2638_29	1286171.EAL2_808p06960	1.14e-179	513.0	COG1301@1|root,COG1301@2|Bacteria,1TPME@1239|Firmicutes,247UX@186801|Clostridia,25UR9@186806|Eubacteriaceae	186801|Clostridia	C	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family	gltT	-	-	-	-	-	-	-	-	-	-	-	SDF
k141_2638_30	290402.Cbei_3358	2.5e-29	128.0	COG0642@1|root,COG2205@2|Bacteria,1TRD2@1239|Firmicutes,247M3@186801|Clostridia,36EWQ@31979|Clostridiaceae	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
k141_2638_31	886882.PPSC2_c1551	4.87e-69	219.0	COG0745@1|root,COG0745@2|Bacteria,1TPQG@1239|Firmicutes,4HFKP@91061|Bacilli,26R4A@186822|Paenibacillaceae	91061|Bacilli	T	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	yycF	-	-	ko:K07658	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
k141_2638_35	702450.CUW_2797	5.26e-48	163.0	COG0778@1|root,COG0778@2|Bacteria,1V4DP@1239|Firmicutes,3VS9J@526524|Erysipelotrichia	526524|Erysipelotrichia	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
k141_2638_36	1321778.HMPREF1982_03391	2.19e-44	160.0	COG2207@1|root,COG3449@1|root,COG2207@2|Bacteria,COG3449@2|Bacteria,1TTAX@1239|Firmicutes,24BT9@186801|Clostridia	186801|Clostridia	K	transcription activator, effector binding	-	-	-	ko:K13652	-	-	-	-	ko00000,ko03000	-	-	-	GyrI-like,HTH_18,HTH_AraC
k141_2638_40	1423321.AS29_16540	4.32e-39	144.0	COG0745@1|root,COG0745@2|Bacteria,1TR8K@1239|Firmicutes,4HBSB@91061|Bacilli,1ZBX5@1386|Bacillus	91061|Bacilli	T	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	cssR	-	-	ko:K07770	ko02020,map02020	M00448	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
k141_2638_41	696281.Desru_0943	6.4e-07	50.4	COG0745@1|root,COG0745@2|Bacteria,1TR8K@1239|Firmicutes,24DTS@186801|Clostridia,261ZH@186807|Peptococcaceae	186801|Clostridia	T	response regulator receiver	cssR	-	-	ko:K07770	ko02020,map02020	M00448	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
k141_2638_43	1123009.AUID01000001_gene1132	2.18e-41	141.0	COG1846@1|root,COG1846@2|Bacteria,1TTM4@1239|Firmicutes,25MWT@186801|Clostridia,26C6C@186813|unclassified Clostridiales	186801|Clostridia	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR
k141_2638_45	1196322.A370_04794	4.09e-76	234.0	COG0500@1|root,COG0500@2|Bacteria,1UHQ8@1239|Firmicutes,25EKK@186801|Clostridia,36USP@31979|Clostridiaceae	186801|Clostridia	Q	Tellurite resistance protein TehB	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_12,Methyltransf_23
k141_2638_46	1293054.HSACCH_02488	5.22e-205	583.0	COG1757@1|root,COG1757@2|Bacteria,1TP8A@1239|Firmicutes,247V4@186801|Clostridia,3WA9C@53433|Halanaerobiales	186801|Clostridia	C	PFAM Na H antiporter	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_antiporter
k141_2638_48	1444309.JAQG01000139_gene1543	2.78e-131	394.0	COG1473@1|root,COG1473@2|Bacteria,1TPEJ@1239|Firmicutes,4HA9M@91061|Bacilli,26SZI@186822|Paenibacillaceae	91061|Bacilli	S	Peptidase dimerisation domain	-	-	-	ko:K12940	-	-	-	-	ko00000,ko01002	-	-	-	M20_dimer,Peptidase_M20
k141_2638_49	1304284.L21TH_2733	1.74e-08	61.2	COG0840@1|root,COG0840@2|Bacteria,1TP5A@1239|Firmicutes,247S3@186801|Clostridia,36EVU@31979|Clostridiaceae	186801|Clostridia	NT	histidine kinase HAMP region domain protein	mcpC3	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal,dCache_1,sCache_2
k141_2638_50	1294265.JCM21738_1801	1.94e-209	593.0	COG3314@1|root,COG3314@2|Bacteria,1TR35@1239|Firmicutes,4HAB6@91061|Bacilli,1ZARZ@1386|Bacillus	91061|Bacilli	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	Gate
k141_2638_51	1410653.JHVC01000002_gene4183	1.29e-12	79.0	COG0840@1|root,COG3221@1|root,COG0840@2|Bacteria,COG3221@2|Bacteria,1TR1Z@1239|Firmicutes,249QC@186801|Clostridia,36EW3@31979|Clostridiaceae	186801|Clostridia	NPT	chemotaxis protein	-	-	-	ko:K02044	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	MCPsignal,Phosphonate-bd
k141_2638_53	744980.TRICHSKD4_1192	3.79e-32	125.0	COG0730@1|root,COG0730@2|Bacteria,1MXNM@1224|Proteobacteria,2TW57@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	membrane transporter protein	-	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
k141_2638_55	1262449.CP6013_3705	1.39e-76	246.0	COG5464@1|root,COG5464@2|Bacteria,1UGME@1239|Firmicutes,248B2@186801|Clostridia,36HRR@31979|Clostridiaceae	186801|Clostridia	S	PFAM transposase YhgA family protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF4351,Transposase_31
k141_5303_1	177437.HRM2_27090	4e-30	119.0	COG0015@1|root,COG0015@2|Bacteria,1MV4B@1224|Proteobacteria,42MYS@68525|delta/epsilon subdivisions,2WJ2E@28221|Deltaproteobacteria,2MIET@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	purB	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ASL_C,Lyase_1
k141_5304_1	1454202.PPBDW_120254___1	9.68e-08	50.4	2DSUI@1|root,33HGN@2|Bacteria,1NH07@1224|Proteobacteria,1SGZT@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_1626_1	575788.VS_2370	9.27e-37	124.0	2E480@1|root,32Z3X@2|Bacteria,1N70N@1224|Proteobacteria,1SD0N@1236|Gammaproteobacteria,1XYHK@135623|Vibrionales	135623|Vibrionales	S	Uncharacterised protein family (UPF0253)	yaeP	-	-	-	-	-	-	-	-	-	-	-	UPF0253
k141_1626_2	675806.VII_002939	1.89e-25	95.5	2EG1V@1|root,339TV@2|Bacteria,1NI0B@1224|Proteobacteria,1SGIA@1236|Gammaproteobacteria,1XZ4Y@135623|Vibrionales	135623|Vibrionales	S	Domain of unknown function (DUF4250)	BT4646	-	-	-	-	-	-	-	-	-	-	-	DUF4250
k141_1626_3	373994.Riv7116_1074	8.43e-32	120.0	COG0500@1|root,COG0500@2|Bacteria,1G9SQ@1117|Cyanobacteria,1HR4H@1161|Nostocales	1117|Cyanobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
k141_2957_1	96561.Dole_1675	1.02e-78	258.0	COG2070@1|root,COG2070@2|Bacteria,1MWMI@1224|Proteobacteria,42P2I@68525|delta/epsilon subdivisions,2WK0M@28221|Deltaproteobacteria,2MIJJ@213118|Desulfobacterales	28221|Deltaproteobacteria	S	TIGRFAM PfaD family protein	-	-	-	-	-	-	-	-	-	-	-	-	NMO
k141_2685_1	177437.HRM2_47180	9.44e-98	319.0	COG0210@1|root,COG0514@1|root,COG0210@2|Bacteria,COG0514@2|Bacteria,1MVGG@1224|Proteobacteria,42MV3@68525|delta/epsilon subdivisions,2WJZB@28221|Deltaproteobacteria,2MHKM@213118|Desulfobacterales	28221|Deltaproteobacteria	L	TIGRFAM ATP-dependent DNA helicase, RecQ	-	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,HRDC,HTH_40,Helicase_C,RQC,RecQ_Zn_bind,UvrD-helicase,UvrD_C
k141_996_2	1280001.BAOA01000136_gene1972	1.77e-96	286.0	COG0179@1|root,COG0179@2|Bacteria,1MVFA@1224|Proteobacteria,1S8KH@1236|Gammaproteobacteria,1XTE3@135623|Vibrionales	135623|Vibrionales	Q	COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)	-	-	-	-	-	-	-	-	-	-	-	-	FAA_hydrolase
k141_996_3	675815.VOA_001206	2.41e-38	132.0	2AW94@1|root,31N4F@2|Bacteria,1QJVW@1224|Proteobacteria,1THXH@1236|Gammaproteobacteria,1XXTY@135623|Vibrionales	135623|Vibrionales	-	-	VPA0521	-	-	-	-	-	-	-	-	-	-	-	-
k141_3305_1	37659.JNLN01000001_gene1060	1.9e-44	160.0	COG0351@1|root,COG2145@1|root,COG0351@2|Bacteria,COG2145@2|Bacteria,1TQ4A@1239|Firmicutes,2483H@186801|Clostridia,36E0S@31979|Clostridiaceae	186801|Clostridia	H	Phosphomethylpyrimidine kinase	thiD	-	2.5.1.3,2.7.1.35,2.7.1.49,2.7.4.7	ko:K00868,ko:K00941,ko:K14153	ko00730,ko00750,ko01100,map00730,map00750,map01100	M00127	R00174,R01909,R02493,R03223,R03471,R04509,R10712	RC00002,RC00017,RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	Phos_pyr_kin
k141_2686_1	1005048.CFU_0118	1.94e-56	189.0	COG3509@1|root,COG3509@2|Bacteria,1NTIV@1224|Proteobacteria,2VKDX@28216|Betaproteobacteria,475E8@75682|Oxalobacteraceae	28216|Betaproteobacteria	M	depolymerase	-	-	3.1.1.75	ko:K05973	ko00650,map00650	-	R05118	-	ko00000,ko00001,ko01000	-	-	-	Esterase_phd
k141_997_1	1304885.AUEY01000088_gene55	9.37e-185	522.0	COG0686@1|root,COG0686@2|Bacteria,1QTX1@1224|Proteobacteria,42MSF@68525|delta/epsilon subdivisions,2WKJ5@28221|Deltaproteobacteria,2MI15@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Belongs to the AlaDH PNT family	ald	-	1.4.1.1	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	-	R00396	RC00008	ko00000,ko00001,ko01000	-	-	iAF987.Gmet_1099	AlaDh_PNT_C,AlaDh_PNT_N
k141_2687_1	717231.Flexsi_0716	8.96e-49	163.0	COG2065@1|root,COG2065@2|Bacteria,2GFEZ@200930|Deferribacteres	200930|Deferribacteres	F	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant	pyrR	-	2.4.2.9	ko:K02825	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000,ko03000	-	-	-	Pribosyltran
k141_2687_2	1304885.AUEY01000020_gene3497	2.87e-56	181.0	COG0521@1|root,COG0521@2|Bacteria,1R9W2@1224|Proteobacteria,42R2A@68525|delta/epsilon subdivisions,2WMUK@28221|Deltaproteobacteria,2MJJX@213118|Desulfobacterales	28221|Deltaproteobacteria	H	May be involved in the biosynthesis of molybdopterin	moaB	-	2.7.7.75	ko:K03638	ko00790,ko01100,map00790,map01100	-	R09726	RC00002	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth
k141_2687_3	96561.Dole_1637	1.5e-31	114.0	2C9KR@1|root,32RPF@2|Bacteria,1MZXP@1224|Proteobacteria,42UJQ@68525|delta/epsilon subdivisions,2WQ5C@28221|Deltaproteobacteria,2MKMB@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_998_1	29495.EA26_15615	7.34e-194	540.0	COG3039@1|root,COG3039@2|Bacteria,1Q9AW@1224|Proteobacteria,1RNU1@1236|Gammaproteobacteria,1XZ6Q@135623|Vibrionales	135623|Vibrionales	L	IR of VSa6	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_3
k141_999_1	933262.AXAM01000003_gene2875	4.05e-91	286.0	COG3276@1|root,COG3276@2|Bacteria,1MWXH@1224|Proteobacteria,42M49@68525|delta/epsilon subdivisions,2WJ5G@28221|Deltaproteobacteria,2MIIX@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Elongation factor SelB winged helix	selB	-	-	ko:K03833	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,SelB-wing_2,SelB-wing_3
k141_5341_1	1291050.JAGE01000001_gene2799	1.21e-33	141.0	COG3299@1|root,COG3299@2|Bacteria,1TRCX@1239|Firmicutes,24BAX@186801|Clostridia,3WI91@541000|Ruminococcaceae	186801|Clostridia	S	Baseplate J-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Baseplate_J
k141_5341_2	1449048.JQKU01000001_gene1938	5.72e-12	76.3	COG3299@1|root,COG3299@2|Bacteria,2GM5C@201174|Actinobacteria,232TR@1762|Mycobacteriaceae	201174|Actinobacteria	S	Baseplate J-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Baseplate_J
k141_5151_88	697281.Mahau_2368	4.24e-214	608.0	COG1129@1|root,COG1129@2|Bacteria,1TP6I@1239|Firmicutes,247II@186801|Clostridia,42ESS@68295|Thermoanaerobacterales	186801|Clostridia	P	Part of the ABC transporter complex XylFGH involved in xylose import. Responsible for energy coupling to the transport system	xylG	-	3.6.3.17	ko:K10441,ko:K10545	ko02010,map02010	M00212,M00215	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19,3.A.1.2.4	-	-	ABC_tran
k141_5151_89	1380408.AVGH01000047_gene2744	1.36e-135	397.0	COG4213@1|root,COG4213@2|Bacteria,1TR3Q@1239|Firmicutes,4HCK3@91061|Bacilli,21UZ3@150247|Anoxybacillus	91061|Bacilli	G	Periplasmic binding protein domain	-	-	-	ko:K02058,ko:K10543	ko02010,map02010	M00215,M00221	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2,3.A.1.2.4	-	-	Peripla_BP_4
k141_5151_90	935837.JAEK01000013_gene4933	1.13e-54	188.0	COG1940@1|root,COG1940@2|Bacteria,1UTWA@1239|Firmicutes,4I34V@91061|Bacilli,1ZMMM@1386|Bacillus	91061|Bacilli	GK	ROK family	-	-	-	-	-	-	-	-	-	-	-	-	ROK
k141_5151_92	572479.Hprae_2073	4.3e-35	138.0	COG2206@1|root,COG2206@2|Bacteria,1TR95@1239|Firmicutes,25AZS@186801|Clostridia,3WCAA@53433|Halanaerobiales	186801|Clostridia	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	HD,HD_5
k141_5151_93	1122925.KB895391_gene1524	1.05e-24	110.0	COG2206@1|root,COG2206@2|Bacteria,1TQIM@1239|Firmicutes,4HBV6@91061|Bacilli,26RX7@186822|Paenibacillaceae	91061|Bacilli	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HD,HD_5
k141_5151_95	1123226.KB899287_gene3594	1.36e-59	194.0	COG0745@1|root,COG0745@2|Bacteria,1TPZ0@1239|Firmicutes,4HE90@91061|Bacilli,26RVQ@186822|Paenibacillaceae	91061|Bacilli	T	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	cseB	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
k141_2135_1	1382359.JIAL01000001_gene2090	2.73e-12	78.6	COG0840@1|root,COG0840@2|Bacteria,3Y3WH@57723|Acidobacteria,2JHR9@204432|Acidobacteriia	204432|Acidobacteriia	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal
k141_513_1	1307761.L21SP2_2649	5.11e-52	182.0	COG0610@1|root,COG0610@2|Bacteria,2J5UU@203691|Spirochaetes	203691|Spirochaetes	V	Subunit R is required for both nuclease and ATPase activities, but not for modification	hsdR	-	3.1.21.3	ko:K01153	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	DUF3387,EcoR124_C,HSDR_N,ResIII
k141_3160_1	1348635.BBJY01000026_gene2274	2.87e-46	156.0	COG1209@1|root,COG1209@2|Bacteria,1MU0X@1224|Proteobacteria,1RMTR@1236|Gammaproteobacteria,1XU3P@135623|Vibrionales	135623|Vibrionales	H	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis	rmlA	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
k141_3160_2	419947.MRA_1518	8.79e-95	284.0	COG0224@1|root,COG0224@2|Bacteria,2ISFK@201174|Actinobacteria,237YF@1762|Mycobacteriaceae	201174|Actinobacteria	C	WbqC-like protein family	-	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	WbqC
k141_3160_3	1509405.GV67_21065	2.7e-113	337.0	COG1216@1|root,COG1216@2|Bacteria,1QVY8@1224|Proteobacteria,2TZC3@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
k141_3160_4	1054217.TALC_00894	3.05e-08	59.7	COG0500@1|root,arCOG03526@1|root,arCOG03526@2157|Archaea,arCOG03529@2157|Archaea	2157|Archaea	Q	Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25,Methyltransf_31
k141_4890_3	29495.EA26_15290	1.71e-311	862.0	COG4988@1|root,COG4988@2|Bacteria,1QU1N@1224|Proteobacteria,1RNPI@1236|Gammaproteobacteria,1XUSA@135623|Vibrionales	135623|Vibrionales	CO	COG4988 ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components	cydD	-	-	ko:K16013	ko02010,map02010	-	-	-	ko00000,ko00001,ko02000	3.A.1.129	-	-	ABC_membrane,ABC_tran
k141_4890_4	945550.VISI1226_22330	6.64e-281	783.0	COG4987@1|root,COG4987@2|Bacteria,1QU1P@1224|Proteobacteria,1RQD7@1236|Gammaproteobacteria,1XUM9@135623|Vibrionales	135623|Vibrionales	CO	COG4987 ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components	cydC	-	-	ko:K16012	ko02010,map02010	-	-	-	ko00000,ko00001,ko02000	3.A.1.129	-	-	ABC_membrane,ABC_tran
k141_1143_1	1121405.dsmv_0418	5.38e-22	100.0	COG0683@1|root,COG1729@1|root,COG0683@2|Bacteria,COG1729@2|Bacteria,1R8IG@1224|Proteobacteria,42N7H@68525|delta/epsilon subdivisions,2WIUQ@28221|Deltaproteobacteria,2MHTC@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Periplasmic binding protein	-	-	-	ko:K07121	-	-	-	-	ko00000	-	-	-	LppC,Peripla_BP_6,TPR_16,TPR_6
k141_4900_2	675815.VOA_003334	0.0	1006.0	COG0568@1|root,COG0568@2|Bacteria,1MVNJ@1224|Proteobacteria,1RMQI@1236|Gammaproteobacteria,1XSGU@135623|Vibrionales	135623|Vibrionales	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	rpoD	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_ner,Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
k141_4900_3	55601.VANGNB10_cI0424c	0.0	921.0	COG0358@1|root,COG0358@2|Bacteria,1MUHC@1224|Proteobacteria,1RMGA@1236|Gammaproteobacteria,1XUTH@135623|Vibrionales	135623|Vibrionales	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB_bind,DnaG_DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2
k141_3855_1	1122201.AUAZ01000025_gene3534	2.83e-261	745.0	COG0643@1|root,COG0643@2|Bacteria,1MUAG@1224|Proteobacteria,1RMS6@1236|Gammaproteobacteria,464CK@72275|Alteromonadaceae	1236|Gammaproteobacteria	NT	COG0643 Chemotaxis protein histidine kinase and related kinases	cheA3	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt
k141_3855_2	395495.Lcho_3797	1.58e-14	71.2	COG1366@1|root,COG1366@2|Bacteria,1N8B6@1224|Proteobacteria,2VWCQ@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Sulfate transporter antisigma-factor antagonist STAS	-	-	-	-	-	-	-	-	-	-	-	-	STAS_2
k141_3855_3	1458275.AZ34_12930	2.62e-61	190.0	COG0745@1|root,COG0745@2|Bacteria,1RHDD@1224|Proteobacteria,2VSKU@28216|Betaproteobacteria,4ADZ6@80864|Comamonadaceae	28216|Betaproteobacteria	T	cheY-homologous receiver domain	-	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
k141_3855_4	1207076.ALAT01000186_gene2894	5.55e-38	147.0	COG0840@1|root,COG0840@2|Bacteria,1NCMF@1224|Proteobacteria,1RRP8@1236|Gammaproteobacteria,1Z38C@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal
k141_3178_1	439235.Dalk_3654	1.92e-72	228.0	COG2159@1|root,COG2159@2|Bacteria,1Q0A4@1224|Proteobacteria,42Q9N@68525|delta/epsilon subdivisions,2WJTE@28221|Deltaproteobacteria,2MI7C@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Amidohydrolase	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
k141_3178_2	1304885.AUEY01000017_gene3728	9.04e-64	199.0	COG0219@1|root,COG0219@2|Bacteria,1RCY4@1224|Proteobacteria,42RJX@68525|delta/epsilon subdivisions,2WQNR@28221|Deltaproteobacteria,2MJWZ@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide	trmL	-	2.1.1.207	ko:K03216	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
k141_3178_3	933262.AXAM01000009_gene1493	5.64e-254	702.0	COG2046@1|root,COG2046@2|Bacteria,1MUQB@1224|Proteobacteria,42NAI@68525|delta/epsilon subdivisions,2WJYY@28221|Deltaproteobacteria,2MIP2@213118|Desulfobacterales	28221|Deltaproteobacteria	P	sulfate adenylyltransferase	sat	-	2.7.1.25,2.7.7.4	ko:K00958,ko:K13811	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00509,R00529,R04928,R04929	RC00002,RC00078,RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase,ATP-sulfurylase,PUA_2
k141_3178_4	1173024.KI912149_gene6408	0.0	941.0	COG1049@1|root,COG1049@2|Bacteria,1G12I@1117|Cyanobacteria,1JGXC@1189|Stigonemataceae	1117|Cyanobacteria	C	Aconitate B N-terminal domain	acnB	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0003994,GO:0005488,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009056,GO:0009060,GO:0009062,GO:0009987,GO:0015980,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017001,GO:0017144,GO:0019541,GO:0019543,GO:0019626,GO:0019629,GO:0019752,GO:0032787,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0045333,GO:0046395,GO:0046459,GO:0047456,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0072329,GO:0072350,GO:0097159,GO:1901363,GO:1901575	4.2.1.3,4.2.1.99	ko:K01682	ko00020,ko00630,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173	R01324,R01325,R01900,R04425	RC00497,RC00498,RC00618,RC01153	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_2_N,Aconitase_B_N
k141_4901_1	1035193.HMPREF9073_01716	2.7e-41	158.0	COG1132@1|root,COG1132@2|Bacteria,4NGTR@976|Bacteroidetes,1I7SW@117743|Flavobacteriia,1ERSX@1016|Capnocytophaga	976|Bacteroidetes	V	ABC transporter transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
k141_3856_1	2002.JOEQ01000021_gene6747	6.02e-08	54.3	COG2197@1|root,COG2197@2|Bacteria,2GIXB@201174|Actinobacteria,4EHV8@85012|Streptosporangiales	201174|Actinobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
k141_4577_1	345073.VC395_0199	4.4e-08	53.5	COG0168@1|root,COG0168@2|Bacteria,1MUIJ@1224|Proteobacteria,1RMN6@1236|Gammaproteobacteria,1XU4M@135623|Vibrionales	135623|Vibrionales	P	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA	trkH	GO:0003674,GO:0005215,GO:0005216,GO:0005261,GO:0005267,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015267,GO:0015318,GO:0015672,GO:0016020,GO:0016021,GO:0022803,GO:0022838,GO:0022857,GO:0022890,GO:0030001,GO:0030955,GO:0031224,GO:0031226,GO:0031420,GO:0034220,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0044425,GO:0044459,GO:0044464,GO:0046872,GO:0046873,GO:0046983,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0098655,GO:0098660,GO:0098662	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
k141_4577_2	672.VV93_v1c00190	1.76e-106	313.0	COG1739@1|root,COG1739@2|Bacteria,1NFJC@1224|Proteobacteria,1RPBF@1236|Gammaproteobacteria,1XTYV@135623|Vibrionales	135623|Vibrionales	S	Domain of unknown function (DUF1949)	yigZ	-	-	-	-	-	-	-	-	-	-	-	DUF1949,UPF0029
k141_4577_3	1219080.VEZ01S_50_00040	9.27e-158	481.0	COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,1RMZ8@1236|Gammaproteobacteria,1XUGA@135623|Vibrionales	135623|Vibrionales	I	Involved in the aerobic and anaerobic degradation of long-chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate	fadB	GO:0003674,GO:0003824,GO:0003857,GO:0004165,GO:0004300,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0008692,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016491,GO:0016614,GO:0016616,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016854,GO:0016856,GO:0016860,GO:0016863,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575	1.1.1.35,4.2.1.17,5.1.2.3,5.3.3.8	ko:K01825	ko00071,ko00280,ko00281,ko00310,ko00362,ko00380,ko00410,ko00640,ko00650,ko00903,ko00930,ko01040,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00071,map00280,map00281,map00310,map00362,map00380,map00410,map00640,map00650,map00903,map00930,map01040,map01100,map01110,map01120,map01130,map01200,map01212	M00032,M00087	R01975,R03026,R03045,R03276,R04137,R04170,R04203,R04204,R04224,R04737,R04738,R04739,R04740,R04741,R04744,R04745,R04746,R04748,R04749,R04756,R05066,R05305,R06411,R06412,R06941,R06942,R07935,R07951,R08093,R08094	RC00029,RC00099,RC00117,RC00241,RC00525,RC00831,RC00834,RC00896,RC01078,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	3HCDH,3HCDH_N,ECH_1
k141_4577_4	29495.EA26_00760	5.55e-215	606.0	COG1207@1|root,COG1207@2|Bacteria,1MUPH@1224|Proteobacteria,1RNKE@1236|Gammaproteobacteria,1XTBG@135623|Vibrionales	135623|Vibrionales	M	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain	glmU	GO:0000270,GO:0000271,GO:0003674,GO:0003824,GO:0003977,GO:0005975,GO:0005976,GO:0006022,GO:0006023,GO:0006024,GO:0006629,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009252,GO:0009273,GO:0009987,GO:0016051,GO:0016740,GO:0016772,GO:0016779,GO:0030203,GO:0033692,GO:0034637,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0070569,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:1903509	2.3.1.157,2.7.7.23	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00362	R00416,R05332	RC00002,RC00004,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transf_3
k141_4577_5	945543.VIBR0546_08234	2.37e-77	232.0	COG0355@1|root,COG0355@2|Bacteria,1RHE4@1224|Proteobacteria,1S25H@1236|Gammaproteobacteria,1XWUZ@135623|Vibrionales	135623|Vibrionales	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpC	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_DE,ATP-synt_DE_N
k141_4577_6	675813.VIB_003005	2.86e-305	836.0	COG0055@1|root,COG0055@2|Bacteria,1MUFU@1224|Proteobacteria,1RN6U@1236|Gammaproteobacteria,1XU5Y@135623|Vibrionales	135623|Vibrionales	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
k141_4577_7	1280001.BAOA01000052_gene1617	5.94e-169	476.0	COG0224@1|root,COG0224@2|Bacteria,1MU28@1224|Proteobacteria,1RNWJ@1236|Gammaproteobacteria,1XTEZ@135623|Vibrionales	135623|Vibrionales	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
k141_4577_8	672.VV93_v1c29750	0.0	917.0	COG0056@1|root,COG0056@2|Bacteria,1MUG7@1224|Proteobacteria,1RP4V@1236|Gammaproteobacteria,1XUW5@135623|Vibrionales	135623|Vibrionales	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
k141_4577_9	1191299.AJYX01000033_gene3000	3.64e-92	273.0	COG0712@1|root,COG0712@2|Bacteria,1MVRH@1224|Proteobacteria,1S8X2@1236|Gammaproteobacteria,1XU7W@135623|Vibrionales	135623|Vibrionales	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpH	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	OSCP
k141_4577_10	1238450.VIBNISOn1_1220018	9.96e-59	186.0	COG0711@1|root,COG0711@2|Bacteria,1RHZ0@1224|Proteobacteria,1S402@1236|Gammaproteobacteria,1XVBF@135623|Vibrionales	135623|Vibrionales	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	atpF	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045263,GO:0045264,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
k141_4577_11	1188252.AJYK01000022_gene1341	2.11e-43	142.0	COG0636@1|root,32S3K@2|Bacteria,1N1NA@1224|Proteobacteria,1S9MD@1236|Gammaproteobacteria,1XYD9@135623|Vibrionales	135623|Vibrionales	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpE	-	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
k141_4577_14	1348635.BBJY01000022_gene1952	2.21e-123	361.0	COG1475@1|root,COG1475@2|Bacteria,1MW2E@1224|Proteobacteria,1RN65@1236|Gammaproteobacteria,1XUPW@135623|Vibrionales	135623|Vibrionales	K	Belongs to the ParB family	parB	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
k141_4577_15	55601.VANGNB10_cI2709c	2e-165	464.0	COG1192@1|root,COG1192@2|Bacteria,1MV43@1224|Proteobacteria,1RNJK@1236|Gammaproteobacteria,1XT92@135623|Vibrionales	135623|Vibrionales	D	COG1192 ATPases involved in chromosome partitioning	parA	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
k141_4577_16	945550.VISI1226_16985	4.62e-115	334.0	COG0357@1|root,COG0357@2|Bacteria,1MY0K@1224|Proteobacteria,1RMRZ@1236|Gammaproteobacteria,1XSMQ@135623|Vibrionales	135623|Vibrionales	J	Specifically methylates the N7 position of guanine in position 527 of 16S rRNA	rsmG	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.170	ko:K03501	-	-	-	-	ko00000,ko01000,ko03009,ko03036	-	-	-	GidB
k141_2434_2	675813.VIB_001820	0.0	970.0	COG2159@1|root,COG2159@2|Bacteria,1PK3Y@1224|Proteobacteria,1T9KT@1236|Gammaproteobacteria,1XZNH@135623|Vibrionales	135623|Vibrionales	S	AIPR protein	-	-	-	-	-	-	-	-	-	-	-	-	AIPR
k141_2434_3	1238450.VIBNISOn1_30019	3.48e-62	198.0	COG3896@1|root,COG3896@2|Bacteria,1NEN0@1224|Proteobacteria,1STA5@1236|Gammaproteobacteria,1XZBC@135623|Vibrionales	135623|Vibrionales	V	Chloramphenicol phosphotransferase-like protein	-	-	-	ko:K18554	-	-	-	-	br01600,ko00000,ko01000,ko01504	-	-	-	CPT
k141_2434_5	1190603.AJYD01000015_gene1006	7.78e-72	219.0	COG1813@1|root,COG1813@2|Bacteria,1QZ14@1224|Proteobacteria,1T3ZF@1236|Gammaproteobacteria,1XWYG@135623|Vibrionales	135623|Vibrionales	K	2TM domain	-	-	-	-	-	-	-	-	-	-	-	-	2TM,HTH_3
k141_2434_6	998088.B565_0018	2.31e-74	253.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,1RN52@1236|Gammaproteobacteria,1Y4Z4@135624|Aeromonadales	135624|Aeromonadales	T	Periplasmic sensor domain found in signal transduction proteins	-	-	-	-	-	-	-	-	-	-	-	-	CHASE5,HATPase_c,PAS_9
k141_2434_7	400668.Mmwyl1_2743	3.82e-158	461.0	COG0840@1|root,COG3829@1|root,COG0840@2|Bacteria,COG3829@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	NT	chemotaxis, protein	-	-	-	ko:K03406,ko:K05875	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CHASE3,HAMP,MCPsignal,TarH,dCache_1
k141_2434_8	742735.HMPREF9467_04087	4.64e-154	440.0	COG1957@1|root,COG1957@2|Bacteria,1TSSS@1239|Firmicutes,24A4D@186801|Clostridia,21XT8@1506553|Lachnoclostridium	186801|Clostridia	F	Inosine-uridine preferring nucleoside hydrolase	rihB	-	3.2.2.8	ko:K10213,ko:K12700	ko00230,ko00240,ko01100,map00230,map00240,map01100	-	R01245,R01677,R01770,R02137	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	IU_nuc_hydro
k141_2434_9	1090318.ATTI01000001_gene647	1.06e-44	149.0	COG1733@1|root,COG1733@2|Bacteria,1MZ6N@1224|Proteobacteria,2UAGH@28211|Alphaproteobacteria,2K6K0@204457|Sphingomonadales	204457|Sphingomonadales	K	HxlR-like helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HxlR
k141_2434_10	1577887.JSYG01000009_gene632	4.01e-178	506.0	COG1902@1|root,COG1902@2|Bacteria,1MVIX@1224|Proteobacteria,1RMFI@1236|Gammaproteobacteria,2JC18@204037|Dickeya	1236|Gammaproteobacteria	C	PFAM NADH flavin oxidoreductase NADH oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_FMN
k141_2434_14	1219076.N646_3694	3.58e-48	165.0	COG1261@1|root,COG1261@2|Bacteria,1N1SA@1224|Proteobacteria,1S8SQ@1236|Gammaproteobacteria,1XX1B@135623|Vibrionales	135623|Vibrionales	N	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly	-	-	-	ko:K02386	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	ChapFlgA
k141_2434_15	1280001.BAOA01000050_gene1433	5.7e-55	174.0	COG1815@1|root,COG1815@2|Bacteria,1MZ8P@1224|Proteobacteria,1S9DS@1236|Gammaproteobacteria,1XXCT@135623|Vibrionales	135623|Vibrionales	N	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body	-	-	-	ko:K02387	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod
k141_2434_16	1517681.HW45_18445	2.5e-74	225.0	COG1558@1|root,COG1558@2|Bacteria,1RJB8@1224|Proteobacteria,1S8B7@1236|Gammaproteobacteria,1XWWM@135623|Vibrionales	135623|Vibrionales	N	Belongs to the flagella basal body rod proteins family	-	-	-	ko:K02388	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod,Flg_bbr_C
k141_2434_17	675814.VIC_004757	3.27e-81	249.0	COG1843@1|root,COG1843@2|Bacteria,1R4QI@1224|Proteobacteria,1RRRM@1236|Gammaproteobacteria,1XTYI@135623|Vibrionales	135623|Vibrionales	N	Required for flagellar hook formation. May act as a scaffolding protein	flgD	-	-	ko:K02389	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FLgD_tudor,FlgD,FlgD_ig
k141_2434_18	1348635.BBJY01000019_gene601	1.25e-175	502.0	COG1749@1|root,COG1749@2|Bacteria,1MU5J@1224|Proteobacteria,1RMWX@1236|Gammaproteobacteria,1XV3D@135623|Vibrionales	135623|Vibrionales	N	Flagellar hook protein FlgE	flgE	-	-	ko:K02390	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FlaE,Flg_bb_rod,Flg_bbr_C
k141_2434_19	945543.VIBR0546_10884	3.99e-119	346.0	COG4787@1|root,COG4787@2|Bacteria,1RB11@1224|Proteobacteria,1S20E@1236|Gammaproteobacteria,1XVMK@135623|Vibrionales	135623|Vibrionales	N	flagellar basal body	-	-	-	ko:K02391	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod,Flg_bbr_C
k141_2434_20	223926.28808407	3.28e-150	426.0	COG4786@1|root,COG4786@2|Bacteria,1MVMA@1224|Proteobacteria,1RMJ2@1236|Gammaproteobacteria,1XTV1@135623|Vibrionales	135623|Vibrionales	N	Belongs to the flagella basal body rod proteins family	-	-	-	ko:K02392	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod,Flg_bbr_C
k141_2434_21	1348635.BBJY01000019_gene598	5.16e-108	317.0	COG2063@1|root,COG2063@2|Bacteria,1RDEY@1224|Proteobacteria,1S2XK@1236|Gammaproteobacteria,1XVDX@135623|Vibrionales	135623|Vibrionales	N	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation	-	-	-	ko:K02393	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FlgH
k141_2434_22	314292.VAS14_09894	1.24e-175	500.0	COG1706@1|root,COG1706@2|Bacteria,1MVKW@1224|Proteobacteria,1RMRB@1236|Gammaproteobacteria,1XUVU@135623|Vibrionales	135623|Vibrionales	N	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation	flgI1	-	-	ko:K02394	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FlgI
k141_2434_23	223926.28808410	3.2e-46	156.0	COG3951@1|root,COG3951@2|Bacteria,1NFEC@1224|Proteobacteria,1SEGF@1236|Gammaproteobacteria,1XWX1@135623|Vibrionales	135623|Vibrionales	N	flagellar protein	-	-	-	ko:K02395	-	-	-	-	ko00000,ko02035	-	-	-	Rod-binding
k141_2434_24	675806.VII_000450	6.1e-160	467.0	COG1256@1|root,COG1256@2|Bacteria,1MV2M@1224|Proteobacteria,1RMEA@1236|Gammaproteobacteria,1XT20@135623|Vibrionales	135623|Vibrionales	N	flagellar hook-associated protein	flgK	-	-	ko:K02396	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod,Flg_bbr_C
k141_2434_25	1517681.HW45_18490	4.04e-128	374.0	COG1344@1|root,COG1344@2|Bacteria,1PJUJ@1224|Proteobacteria,1RPNR@1236|Gammaproteobacteria,1XUAC@135623|Vibrionales	135623|Vibrionales	N	Bacterial flagellin N-terminal helical region	flgL	-	-	ko:K02397	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flagellin_N
k141_2434_26	1517681.HW45_18495	5.71e-66	219.0	COG2604@1|root,COG2604@2|Bacteria,1NNJY@1224|Proteobacteria,1SI36@1236|Gammaproteobacteria,1XWMN@135623|Vibrionales	135623|Vibrionales	N	Protein of unknown function DUF115	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_2434_27	1517681.HW45_18500	6.54e-18	79.0	2CHPC@1|root,33C3I@2|Bacteria,1NGVQ@1224|Proteobacteria,1SHND@1236|Gammaproteobacteria,1XYN2@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_2434_28	945543.VIBR0546_10829	2.74e-121	358.0	COG1360@1|root,COG1360@2|Bacteria,1MW1Y@1224|Proteobacteria,1RPQ9@1236|Gammaproteobacteria,1XV9X@135623|Vibrionales	135623|Vibrionales	N	Membrane MotB of proton-channel complex MotA/MotB	-	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K02557	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	MotB_plug,OmpA
k141_2434_29	1248232.BANQ01000151_gene4083	1.69e-164	464.0	COG1291@1|root,COG1291@2|Bacteria,1MXK3@1224|Proteobacteria,1RNTF@1236|Gammaproteobacteria,1XSAJ@135623|Vibrionales	135623|Vibrionales	N	flagellar motor	motA	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K02556	ko02020,ko02030,ko02040,map02020,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	MotA_ExbB
k141_2434_30	314292.VAS14_09964	7.57e-103	305.0	COG1191@1|root,COG1191@2|Bacteria,1RCX0@1224|Proteobacteria,1S4UA@1236|Gammaproteobacteria,1XV95@135623|Vibrionales	135623|Vibrionales	K	Belongs to the sigma-70 factor family	lafS	-	-	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	-	-	-	ko00000,ko00001,ko02035,ko03021	-	-	-	Sigma70_r2,Sigma70_r3,Sigma70_r4
k141_2434_31	796620.VIBC2010_03957	4.63e-53	172.0	COG1580@1|root,COG1580@2|Bacteria,1NC4D@1224|Proteobacteria,1SE3R@1236|Gammaproteobacteria,1XX7B@135623|Vibrionales	135623|Vibrionales	N	Controls the rotational direction of flagella during chemotaxis	lafL	-	-	ko:K02415	-	-	-	-	ko00000,ko02035	-	-	-	FliL
k141_2434_32	1190603.AJYD01000070_gene2317	5.32e-40	153.0	COG3144@1|root,COG3144@2|Bacteria,1N86W@1224|Proteobacteria,1SER0@1236|Gammaproteobacteria,1XXIJ@135623|Vibrionales	135623|Vibrionales	N	Flagellar hook-length control protein FliK	-	-	-	ko:K02414	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_hook
k141_2434_34	796620.VIBC2010_03942	2.32e-58	183.0	COG1516@1|root,COG1516@2|Bacteria,1MZ3G@1224|Proteobacteria,1S9BC@1236|Gammaproteobacteria,1XXKX@135623|Vibrionales	135623|Vibrionales	N	Flagellar protein FliS	fliS	-	-	ko:K02422	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliS
k141_2434_35	675814.VIC_004739	6.26e-154	451.0	COG1345@1|root,COG1345@2|Bacteria,1MUVP@1224|Proteobacteria,1S11E@1236|Gammaproteobacteria,1XUTC@135623|Vibrionales	135623|Vibrionales	N	morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end	-	GO:0005575,GO:0005576,GO:0005623,GO:0009288,GO:0042995,GO:0043226,GO:0043228,GO:0044464	-	ko:K02407	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flagellin_IN,FliD_C,FliD_N
k141_2434_36	1190603.AJYD01000070_gene2305	4.91e-100	302.0	COG1344@1|root,COG1344@2|Bacteria,1MV1N@1224|Proteobacteria,1RN0Y@1236|Gammaproteobacteria,1Y2KM@135623|Vibrionales	135623|Vibrionales	N	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella	-	-	-	-	-	-	-	-	-	-	-	-	Flagellin_C,Flagellin_N
k141_2434_37	314292.VAS14_10009	0.0	1095.0	COG1298@1|root,COG1298@2|Bacteria,1MUF3@1224|Proteobacteria,1RMSM@1236|Gammaproteobacteria,1XSP7@135623|Vibrionales	135623|Vibrionales	N	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin	-	-	-	ko:K02400	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	FHIPEP
k141_2434_38	945543.VIBR0546_21570	5.22e-171	488.0	COG1377@1|root,COG1377@2|Bacteria,1MUWI@1224|Proteobacteria,1RMHA@1236|Gammaproteobacteria,1XUUD@135623|Vibrionales	135623|Vibrionales	N	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin	-	-	-	ko:K02401	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	Bac_export_2
k141_2434_39	223926.28809946	5.93e-112	329.0	COG1684@1|root,COG1684@2|Bacteria,1RCGV@1224|Proteobacteria,1S2MW@1236|Gammaproteobacteria,1XVTR@135623|Vibrionales	135623|Vibrionales	N	Role in flagellar biosynthesis	-	-	-	ko:K02421	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	Bac_export_1
k141_2434_40	1219065.VPR01S_03_01330	2.92e-45	147.0	COG1987@1|root,COG1987@2|Bacteria,1N73W@1224|Proteobacteria,1SCBG@1236|Gammaproteobacteria,1XXWA@135623|Vibrionales	135623|Vibrionales	N	Role in flagellar biosynthesis	-	-	-	ko:K02420	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	Bac_export_3
k141_2434_41	674977.VMC_26030	3.07e-120	350.0	COG1338@1|root,COG1338@2|Bacteria,1MVBU@1224|Proteobacteria,1RMYH@1236|Gammaproteobacteria,1XV0T@135623|Vibrionales	135623|Vibrionales	N	Plays a role in the flagellum-specific transport system	-	-	-	ko:K02419	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	FliP
k141_2434_42	1248232.BANQ01000122_gene633	1.91e-45	150.0	COG1886@1|root,COG1886@2|Bacteria,1N815@1224|Proteobacteria,1SEUM@1236|Gammaproteobacteria,1XXZG@135623|Vibrionales	135623|Vibrionales	N	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation	-	-	-	ko:K02417	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	FliMN_C
k141_2434_43	945543.VIBR0546_21595	4.15e-46	162.0	COG1868@1|root,COG1868@2|Bacteria,1NKVA@1224|Proteobacteria,1SGRG@1236|Gammaproteobacteria,1XUVR@135623|Vibrionales	135623|Vibrionales	N	Type III flagellar switch regulator (C-ring) FliN C-term	-	-	-	-	-	-	-	-	-	-	-	-	FliMN_C
k141_2434_44	1219076.N646_3257	1.32e-53	184.0	COG2885@1|root,COG2885@2|Bacteria,1N6C8@1224|Proteobacteria,1SAU6@1236|Gammaproteobacteria,1XWYH@135623|Vibrionales	135623|Vibrionales	N	Belongs to the ompA family	-	-	-	ko:K21218	ko02040,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	OmpA
k141_2434_45	1190603.AJYD01000070_gene2295	1.38e-217	612.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria,1XVEB@135623|Vibrionales	135623|Vibrionales	T	COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
k141_2434_46	1500893.JQNB01000001_gene59	1.91e-07	53.5	COG1677@1|root,COG1677@2|Bacteria,1N6RZ@1224|Proteobacteria,1SD52@1236|Gammaproteobacteria,1X7II@135614|Xanthomonadales	135614|Xanthomonadales	N	Flagellar hook-basal body complex protein FliE	fliE	-	-	ko:K02408	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliE
k141_2434_47	314292.VAS14_10059	2.03e-244	691.0	COG1766@1|root,COG1766@2|Bacteria,1MUQR@1224|Proteobacteria,1RN6T@1236|Gammaproteobacteria,1XTK5@135623|Vibrionales	135623|Vibrionales	N	The M ring may be actively involved in energy transduction	-	-	-	ko:K02409	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	YscJ_FliF,YscJ_FliF_C
k141_2434_48	1517681.HW45_18615	8.48e-172	487.0	COG1536@1|root,COG1536@2|Bacteria,1MV9X@1224|Proteobacteria,1RM9B@1236|Gammaproteobacteria,1XU8Q@135623|Vibrionales	135623|Vibrionales	N	Flagellar motor switch protein	fliG	-	-	ko:K02410	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliG_C,FliG_N
k141_2434_49	1280001.BAOA01000050_gene1375	2.14e-70	224.0	COG1317@1|root,COG1317@2|Bacteria,1MYX8@1224|Proteobacteria,1S872@1236|Gammaproteobacteria,1XUIE@135623|Vibrionales	135623|Vibrionales	N	COG1317 Flagellar biosynthesis type III secretory pathway protein	-	-	-	ko:K02411	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	FliH
k141_2434_50	1248232.BANQ01000122_gene641	6.07e-253	702.0	COG1157@1|root,COG1157@2|Bacteria,1MUH6@1224|Proteobacteria,1RM9W@1236|Gammaproteobacteria,1XSRA@135623|Vibrionales	135623|Vibrionales	NU	ATP synthase alpha/beta family, nucleotide-binding domain	-	-	3.6.3.14	ko:K02412	ko02040,map02040	-	-	-	ko00000,ko00001,ko01000,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	ATP-synt_ab
k141_2434_51	1219065.VPR01S_03_01220	2.92e-24	98.6	2AX8Y@1|root,31P7W@2|Bacteria,1QIUZ@1224|Proteobacteria,1TGQY@1236|Gammaproteobacteria,1XY8P@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	FliJ
k141_2434_52	1190606.AJYG01000179_gene1536	6.77e-214	603.0	COG0443@1|root,COG0443@2|Bacteria,1MXBT@1224|Proteobacteria,1RN4U@1236|Gammaproteobacteria,1XU0W@135623|Vibrionales	135623|Vibrionales	O	COG0443 Molecular chaperone	T0747	-	-	ko:K04046	-	-	-	-	ko00000,ko03110	1.A.33	-	-	HSP70
k141_2434_53	1348635.BBJY01000002_gene3655	4.74e-278	777.0	COG0204@1|root,COG3176@1|root,COG0204@2|Bacteria,COG3176@2|Bacteria,1MWIM@1224|Proteobacteria,1RQD4@1236|Gammaproteobacteria,1XTB5@135623|Vibrionales	135623|Vibrionales	I	Hemolysin	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_5,Acyltransferase
k141_2434_54	1116375.VEJY3_20541	2.36e-170	481.0	COG2040@1|root,COG2040@2|Bacteria,1QU2A@1224|Proteobacteria,1RS8M@1236|Gammaproteobacteria,1XSGQ@135623|Vibrionales	135623|Vibrionales	H	COG2040 Homocysteine selenocysteine methylase (S-methylmethionine-dependent)	-	-	-	-	-	-	-	-	-	-	-	-	S-methyl_trans
k141_2434_55	1116375.VEJY3_20546	1.12e-239	668.0	COG0531@1|root,COG0531@2|Bacteria,1MUA2@1224|Proteobacteria,1RNND@1236|Gammaproteobacteria,1XUAH@135623|Vibrionales	135623|Vibrionales	E	Arginine ornithine antiporter	ydgI	-	-	ko:K03758	-	-	-	-	ko00000,ko02000	2.A.3.2	-	-	AA_permease_2
k141_2015_1	439235.Dalk_1286	6.29e-171	503.0	COG3290@1|root,COG3829@1|root,COG3290@2|Bacteria,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,42N7Y@68525|delta/epsilon subdivisions,2WIX7@28221|Deltaproteobacteria,2MI5M@213118|Desulfobacterales	28221|Deltaproteobacteria	KT	Sigma-54 interaction domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,HTH_8,PAS,PAS_8,PAS_9,Sigma54_activat
k141_2015_2	439235.Dalk_1215	4.21e-306	839.0	COG2368@1|root,COG2368@2|Bacteria,1PEQG@1224|Proteobacteria,42NUH@68525|delta/epsilon subdivisions,2WISE@28221|Deltaproteobacteria,2MI4T@213118|Desulfobacterales	28221|Deltaproteobacteria	Q	PFAM 4-hydroxyphenylacetate 3-hydroxylase N terminal	-	-	4.2.1.120,5.3.3.3	ko:K14534	ko00650,ko00720,ko01100,ko01120,ko01200,map00650,map00720,map01100,map01120,map01200	M00374,M00375	R03031,R10782	RC01857,RC03277	ko00000,ko00001,ko00002,ko01000	-	-	-	HpaB,HpaB_N
k141_2015_3	1265505.ATUG01000002_gene2478	3.75e-207	588.0	COG0427@1|root,COG0427@2|Bacteria,1MUGE@1224|Proteobacteria,42MHC@68525|delta/epsilon subdivisions,2WINZ@28221|Deltaproteobacteria,2MI87@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM Acetyl-CoA hydrolase transferase	-	-	-	ko:K18122	ko00650,ko01100,ko01200,map00650,map01100,map01200	-	R05336	RC00012,RC00014	ko00000,ko00001,ko01000	-	-	-	AcetylCoA_hyd_C,AcetylCoA_hydro,Acetyltransf_1
k141_2015_4	439235.Dalk_1218	8.93e-269	745.0	COG0659@1|root,COG0659@2|Bacteria,1R3RX@1224|Proteobacteria,42PC7@68525|delta/epsilon subdivisions,2WIXJ@28221|Deltaproteobacteria,2MIZX@213118|Desulfobacterales	28221|Deltaproteobacteria	P	secondary active sulfate transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_3723_1	1224318.DT73_20965	1.66e-29	115.0	COG1009@1|root,COG1009@2|Bacteria,1MW9F@1224|Proteobacteria,1RN54@1236|Gammaproteobacteria	1236|Gammaproteobacteria	CP	NADH ubiquinone oxidoreductase subunit 5 (chain L) multisubunit Na H antiporter MnhA subunit	-	-	1.6.5.3	ko:K05577	ko00190,ko01100,map00190,map01100	M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	-	-	-	Proton_antipo_M,Proton_antipo_N
k141_3723_2	1515746.HR45_09620	4.19e-165	466.0	COG0583@1|root,COG0583@2|Bacteria,1MVHT@1224|Proteobacteria,1RN7G@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	transcriptional regulator	nhaR	-	-	ko:K03717	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,LysR_substrate
k141_2016_1	744872.Spica_1424	7.43e-65	213.0	COG0305@1|root,COG0305@2|Bacteria,2J590@203691|Spirochaetes	203691|Spirochaetes	L	Participates in initiation and elongation during chromosome replication	dnaB	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
k141_1563_1	246196.MSMEI_3283	4.23e-10	63.9	COG1309@1|root,COG1309@2|Bacteria,2HU1G@201174|Actinobacteria,238ST@1762|Mycobacteriaceae	201174|Actinobacteria	K	Bacterial transcriptional repressor C-terminal	-	-	-	ko:K16137	-	-	-	-	ko00000,ko03000	-	-	-	TetR_C_13,TetR_N
k141_2340_1	1124982.MSI_04440	1.05e-14	82.4	COG0840@1|root,COG4564@1|root,COG0840@2|Bacteria,COG4564@2|Bacteria,2J6XS@203691|Spirochaetes	203691|Spirochaetes	NT	Methyl-accepting chemotaxis protein (MCP) signaling domain	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal,sCache_2
k141_5001_1	1120970.AUBZ01000003_gene163	5.88e-196	577.0	COG4191@1|root,COG4191@2|Bacteria,1MU55@1224|Proteobacteria,1RQ5N@1236|Gammaproteobacteria,4643T@72275|Alteromonadaceae	1236|Gammaproteobacteria	T	COG0642 Signal transduction histidine kinase	prsK	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c
k141_5001_2	754436.JCM19237_3660	1.52e-45	157.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria,1XZRV@135623|Vibrionales	135623|Vibrionales	T	Sigma-54 interaction domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
k141_2341_1	1121374.KB891585_gene2413	1.63e-46	156.0	COG0204@1|root,COG0204@2|Bacteria,1RJMS@1224|Proteobacteria,1S71V@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	Acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
k141_2341_2	1307759.JOMJ01000003_gene2339	5.29e-56	179.0	COG1733@1|root,COG1733@2|Bacteria,1MZ6G@1224|Proteobacteria,42V7W@68525|delta/epsilon subdivisions,2WPHM@28221|Deltaproteobacteria,2MC6B@213115|Desulfovibrionales	28221|Deltaproteobacteria	K	PFAM helix-turn-helix HxlR type	-	-	-	-	-	-	-	-	-	-	-	-	HxlR
k141_3277_1	177437.HRM2_40560	5.53e-87	305.0	COG0715@1|root,COG0834@1|root,COG2199@1|root,COG0715@2|Bacteria,COG0834@2|Bacteria,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,42MCD@68525|delta/epsilon subdivisions,2X5DF@28221|Deltaproteobacteria,2MQ2Z@213118|Desulfobacterales	28221|Deltaproteobacteria	EPT	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,NMT1,SBP_bac_3
k141_5012_3	324925.Ppha_2145	7.33e-131	416.0	COG0784@1|root,COG1956@1|root,COG2202@1|root,COG2203@1|root,COG3829@1|root,COG4191@1|root,COG0784@2|Bacteria,COG1956@2|Bacteria,COG2202@2|Bacteria,COG2203@2|Bacteria,COG3829@2|Bacteria,COG4191@2|Bacteria,1FEIU@1090|Chlorobi	1090|Chlorobi	T	ATP-binding region, ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
k141_4330_2	945550.VISI1226_01550	1.35e-64	206.0	COG0583@1|root,COG0583@2|Bacteria,1MWVU@1224|Proteobacteria,1RPT8@1236|Gammaproteobacteria,1XTZM@135623|Vibrionales	135623|Vibrionales	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
k141_1575_1	1051646.VITU9109_15848	6.04e-15	72.8	COG0447@1|root,COG0447@2|Bacteria,1QTZ2@1224|Proteobacteria,1T1TZ@1236|Gammaproteobacteria,1XVFY@135623|Vibrionales	135623|Vibrionales	H	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)	menB	-	4.1.3.36	ko:K01661	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R07263	RC01923	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
k141_1575_2	675813.VIB_001581	4.72e-73	231.0	COG2267@1|root,COG2267@2|Bacteria,1QUFU@1224|Proteobacteria,1T1XG@1236|Gammaproteobacteria,1XSP9@135623|Vibrionales	135623|Vibrionales	H	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)	menH	-	4.2.99.20	ko:K08680	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R08166	RC02148,RC02475	ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_1,Abhydrolase_6
k141_1575_3	55601.VANGNB10_cI1811c	8e-126	379.0	COG1165@1|root,COG1165@2|Bacteria,1MVMZ@1224|Proteobacteria,1RNRS@1236|Gammaproteobacteria,1XSZF@135623|Vibrionales	135623|Vibrionales	H	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)	menD	GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0008683,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0016833,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663	2.2.1.9	ko:K02551	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R08165	RC02186	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M_2,TPP_enzyme_N
k141_2925_1	933262.AXAM01000022_gene3227	6.76e-117	354.0	COG1960@1|root,COG1960@2|Bacteria,1MU20@1224|Proteobacteria,42N2H@68525|delta/epsilon subdivisions,2WMIR@28221|Deltaproteobacteria,2MIIF@213118|Desulfobacterales	28221|Deltaproteobacteria	I	Acyl-CoA dehydrogenase N terminal	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_C,Acyl-CoA_dh_M,Acyl-CoA_dh_N,AcylCoA_DH_N
k141_4331_1	998088.B565_3780	2.24e-28	118.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,1Y3R2@135624|Aeromonadales	135624|Aeromonadales	NT	Cache domain	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal,dCache_1
k141_2371_1	1265505.ATUG01000001_gene3881	4.29e-164	488.0	COG5009@1|root,COG5009@2|Bacteria,1MU5A@1224|Proteobacteria,42MJB@68525|delta/epsilon subdivisions,2WIXF@28221|Deltaproteobacteria,2MI9W@213118|Desulfobacterales	28221|Deltaproteobacteria	M	TIGRFAM penicillin-binding protein, 1A family	mrcA	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	iAF987.Gmet_0354	PCB_OB,Transgly,Transpeptidase
k141_2926_2	1331660.L313_0757	7.93e-07	52.0	COG1253@1|root,COG1253@2|Bacteria,1MWT3@1224|Proteobacteria,1RQBC@1236|Gammaproteobacteria,3NMEH@468|Moraxellaceae	1236|Gammaproteobacteria	S	Domain of unknown function DUF21	-	-	-	-	-	-	-	-	-	-	-	-	CBS,DUF21
k141_929_1	55601.VANGNB10_cI0950	4.5e-67	216.0	COG0349@1|root,COG0349@2|Bacteria,1MURV@1224|Proteobacteria,1RPBP@1236|Gammaproteobacteria,1XSSU@135623|Vibrionales	135623|Vibrionales	J	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides	rnd	-	3.1.13.5	ko:K03684	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DNA_pol_A_exo1,HRDC
k141_929_4	298386.PBPRA1079	2.29e-51	169.0	COG0850@1|root,COG0850@2|Bacteria,1RHVN@1224|Proteobacteria,1S6K8@1236|Gammaproteobacteria,1Y304@135623|Vibrionales	135623|Vibrionales	D	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization	minC	-	-	ko:K03610	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	MinC_C,MinC_N
k141_4332_1	1265505.ATUG01000002_gene1547	3.47e-51	167.0	COG1802@1|root,COG1802@2|Bacteria,1MWG2@1224|Proteobacteria,42P4Y@68525|delta/epsilon subdivisions,2WM8E@28221|Deltaproteobacteria,2MM79@213118|Desulfobacterales	28221|Deltaproteobacteria	K	helix_turn_helix gluconate operon transcriptional repressor	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
k141_1576_2	882.DVU_0599	2.21e-97	300.0	COG1966@1|root,COG1966@2|Bacteria,1MWF9@1224|Proteobacteria,42NBI@68525|delta/epsilon subdivisions,2WKNF@28221|Deltaproteobacteria,2M89B@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	carbon starvation protein	-	-	-	-	-	-	-	-	-	-	-	-	CstA,CstA_5TM
k141_2927_1	706587.Desti_1429	4.88e-69	226.0	COG0446@1|root,COG0446@2|Bacteria,1NR3M@1224|Proteobacteria,42N3G@68525|delta/epsilon subdivisions,2WIS9@28221|Deltaproteobacteria,2MRA2@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	Pyridine nucleotide-disulphide oxidoreductase, dimerisation	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Pyr_redox_dim
k141_4028_1	642492.Clole_1513	3.35e-09	63.5	COG1835@1|root,COG1835@2|Bacteria,1UXXI@1239|Firmicutes,24GFT@186801|Clostridia	186801|Clostridia	I	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
k141_2928_1	879212.DespoDRAFT_02066	7.23e-55	183.0	COG1883@1|root,COG1883@2|Bacteria,1MV0G@1224|Proteobacteria,42MH1@68525|delta/epsilon subdivisions,2WJD7@28221|Deltaproteobacteria,2MIY0@213118|Desulfobacterales	28221|Deltaproteobacteria	C	TIGRFAM sodium ion-translocating decarboxylase, beta subunit	-	-	4.1.1.3	ko:K01572	ko00620,ko01100,map00620,map01100	-	R00217	RC00040	ko00000,ko00001,ko01000,ko02000	3.B.1.1.1	-	-	OAD_beta
k141_4333_1	1265505.ATUG01000001_gene4304	6.72e-142	409.0	COG0379@1|root,COG0379@2|Bacteria,1MWQU@1224|Proteobacteria,42N99@68525|delta/epsilon subdivisions,2WJY8@28221|Deltaproteobacteria,2MIM2@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate	nadA	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.5.1.72	ko:K03517	ko00760,ko01100,map00760,map01100	M00115	R04292	RC01119	ko00000,ko00001,ko00002,ko01000	-	-	-	NadA
k141_4333_2	177437.HRM2_04010	1.02e-26	108.0	COG2834@1|root,COG2834@2|Bacteria,1PDTV@1224|Proteobacteria,42TAB@68525|delta/epsilon subdivisions,2WPXY@28221|Deltaproteobacteria,2MK70@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)	lolA	-	-	ko:K03634	-	-	-	-	ko00000	-	-	-	LolA
k141_2373_1	933262.AXAM01000022_gene3227	3.84e-267	746.0	COG1960@1|root,COG1960@2|Bacteria,1MU20@1224|Proteobacteria,42N2H@68525|delta/epsilon subdivisions,2WMIR@28221|Deltaproteobacteria,2MIIF@213118|Desulfobacterales	28221|Deltaproteobacteria	I	Acyl-CoA dehydrogenase N terminal	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_C,Acyl-CoA_dh_M,Acyl-CoA_dh_N,AcylCoA_DH_N
k141_5269_2	498211.CJA_1620	2.97e-260	727.0	COG1232@1|root,COG1232@2|Bacteria,1QX3T@1224|Proteobacteria,1T3RT@1236|Gammaproteobacteria	1236|Gammaproteobacteria	H	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
k141_5269_3	1001530.BACE01000027_gene690	5.99e-249	706.0	COG0493@1|root,COG0493@2|Bacteria,1MU2H@1224|Proteobacteria,1SMV9@1236|Gammaproteobacteria,1Y32S@135623|Vibrionales	135623|Vibrionales	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Fer2_4,Fer4,Fer4_20,Fer4_7,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,Pyr_redox_2
k141_5269_4	243277.VC_0869	0.0	2241.0	COG0046@1|root,COG0047@1|root,COG0046@2|Bacteria,COG0047@2|Bacteria,1MYN4@1224|Proteobacteria,1RMRN@1236|Gammaproteobacteria,1XTXA@135623|Vibrionales	135623|Vibrionales	F	Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate	purL	GO:0003674,GO:0003824,GO:0004642,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS_C,GATase_5
k141_1577_2	111781.Lepto7376_0117	1.06e-38	139.0	COG3264@1|root,COG3264@2|Bacteria,1GQRF@1117|Cyanobacteria	1117|Cyanobacteria	M	PFAM Mechanosensitive ion channel MscS	-	-	-	ko:K03442	-	-	-	-	ko00000,ko02000	1.A.23.2	-	-	MS_channel
k141_4740_2	1304885.AUEY01000084_gene2331	2.71e-43	162.0	COG2114@1|root,COG4252@1|root,COG2114@2|Bacteria,COG4252@2|Bacteria,1MV1V@1224|Proteobacteria,42N5S@68525|delta/epsilon subdivisions,2WIUS@28221|Deltaproteobacteria,2MHQU@213118|Desulfobacterales	28221|Deltaproteobacteria	T	adenylyl cyclase class-3 4 guanylyl cyclase	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	CHASE2,Guanylate_cyc
k141_930_1	400668.Mmwyl1_0498	8.54e-156	445.0	COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,1S8PT@1236|Gammaproteobacteria,1XP3S@135619|Oceanospirillales	135619|Oceanospirillales	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
k141_930_2	1116375.VEJY3_22211	8.43e-153	435.0	COG0329@1|root,COG0329@2|Bacteria,1R4AY@1224|Proteobacteria,1RRPJ@1236|Gammaproteobacteria,1XXME@135623|Vibrionales	135623|Vibrionales	EM	Dihydrodipicolinate synthetase family	-	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
k141_2374_1	933262.AXAM01000018_gene1005	2.75e-144	422.0	COG0029@1|root,COG0029@2|Bacteria,1RBQW@1224|Proteobacteria,43BKD@68525|delta/epsilon subdivisions,2WJNK@28221|Deltaproteobacteria,2MIMB@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Catalyzes the oxidation of L-aspartate to iminoaspartate	nadB	-	1.4.3.16	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	M00115	R00357,R00481	RC00006,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
k141_657_1	485915.Dret_2378	0.0	1203.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2WJN5@28221|Deltaproteobacteria,2MG2T@213115|Desulfovibrionales	28221|Deltaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k141_657_2	626887.J057_17605	1.92e-60	208.0	COG0845@1|root,COG0845@2|Bacteria,1PEVY@1224|Proteobacteria,1RPEQ@1236|Gammaproteobacteria,466EU@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	Barrel-sandwich domain of CusB or HlyD membrane-fusion	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
k141_657_3	177439.DP2835	1.07e-49	183.0	COG1538@1|root,COG1538@2|Bacteria,1MUA8@1224|Proteobacteria,42MU2@68525|delta/epsilon subdivisions,2WM00@28221|Deltaproteobacteria,2MKCR@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
k141_657_4	385682.AFSL01000056_gene1986	2.18e-11	67.4	COG1595@1|root,COG1595@2|Bacteria,4NQTP@976|Bacteroidetes,2FU81@200643|Bacteroidia	976|Bacteroidetes	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
k141_931_1	1336233.JAEH01000004_gene1672	4.4e-60	191.0	COG0110@1|root,COG0110@2|Bacteria,1N6SQ@1224|Proteobacteria,1SCHA@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Acetyltransferase (isoleucine patch	-	-	2.3.1.79	ko:K00661	-	-	-	-	ko00000,ko01000	-	-	-	Capsule_synth,Hexapep,Hexapep_2,Mac
k141_2929_1	926561.KB900619_gene2448	8.05e-10	70.1	COG2909@1|root,COG2909@2|Bacteria,1UIMV@1239|Firmicutes,25GAH@186801|Clostridia,3WC0E@53433|Halanaerobiales	186801|Clostridia	K	Bacterial transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22,BTAD
k141_4335_2	1121448.DGI_1071	1.49e-20	97.8	COG0642@1|root,COG0834@1|root,COG5002@1|root,COG0834@2|Bacteria,COG2205@2|Bacteria,COG5002@2|Bacteria,1NRP8@1224|Proteobacteria,43DFB@68525|delta/epsilon subdivisions,2X8M9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
k141_5014_1	667014.Thein_0453	6.73e-19	83.6	COG1516@1|root,COG1516@2|Bacteria,2GHV4@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	N	Flagellar protein FliS	-	-	-	ko:K02422	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliS
k141_5014_2	297246.lpp1292	3.12e-21	104.0	COG1345@1|root,COG1345@2|Bacteria,1MUVP@1224|Proteobacteria,1RS2S@1236|Gammaproteobacteria,1JD0G@118969|Legionellales	118969|Legionellales	N	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end	fliD	-	-	ko:K02407	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flagellin_IN,FliD_C,FliD_N
k141_5014_3	1304885.AUEY01000025_gene2758	6.6e-180	543.0	COG1344@1|root,COG1344@2|Bacteria,1MV1N@1224|Proteobacteria,42MX8@68525|delta/epsilon subdivisions,2WJRC@28221|Deltaproteobacteria,2MISQ@213118|Desulfobacterales	28221|Deltaproteobacteria	N	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella	-	-	-	ko:K02406	ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flagellin_C,Flagellin_IN,Flagellin_N
k141_2375_1	575788.VS_II1088	7.14e-110	324.0	COG0600@1|root,COG0600@2|Bacteria,1N0FV@1224|Proteobacteria,1RPE6@1236|Gammaproteobacteria,1XSYY@135623|Vibrionales	135623|Vibrionales	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K15599	ko02010,map02010	M00442	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.17.3,3.A.1.17.6	-	-	BPD_transp_1
k141_2375_2	1136163.M565_ctg5P0896	1.4e-50	170.0	COG0715@1|root,COG0715@2|Bacteria,1MVRA@1224|Proteobacteria,1RNG0@1236|Gammaproteobacteria,1XUZM@135623|Vibrionales	135623|Vibrionales	P	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components	-	-	-	ko:K15598	ko02010,map02010	M00442	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.17.3,3.A.1.17.6	-	-	NMT1
k141_5270_2	641491.DND132_1231	9.6e-169	475.0	COG2043@1|root,COG2043@2|Bacteria,1R8EH@1224|Proteobacteria,42Q2F@68525|delta/epsilon subdivisions,2WJZN@28221|Deltaproteobacteria,2M8RH@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Uncharacterised ArCR, COG2043	-	-	-	-	-	-	-	-	-	-	-	-	DUF169
k141_2611_1	398720.MED217_06337	3.76e-59	203.0	COG1409@1|root,COG1409@2|Bacteria,4NJT0@976|Bacteroidetes,1I0D5@117743|Flavobacteriia	976|Bacteroidetes	P	metallophosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Pur_ac_phosph_N
k141_2611_3	717231.Flexsi_0334	2.94e-17	85.1	COG1802@1|root,COG1802@2|Bacteria,2GER1@200930|Deferribacteres	200930|Deferribacteres	K	FCD	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
k141_2611_4	457570.Nther_0882	7.01e-179	511.0	COG5441@1|root,COG5441@2|Bacteria,1TQ3W@1239|Firmicutes,24A9D@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	UPF0261
k141_2611_5	1382305.AZUC01000052_gene3112	2.15e-151	431.0	COG5564@1|root,COG5564@2|Bacteria,1TS71@1239|Firmicutes,4HB79@91061|Bacilli,26GJB@186818|Planococcaceae	91061|Bacilli	S	Phosphoenolpyruvate hydrolase-like	-	-	-	-	-	-	-	-	-	-	-	-	PEP_hydrolase
k141_2611_6	1408437.JNJN01000002_gene1461	6.22e-61	224.0	COG0643@1|root,COG2198@1|root,COG0643@2|Bacteria,COG2198@2|Bacteria,1TPMS@1239|Firmicutes,24858@186801|Clostridia,25VH8@186806|Eubacteriaceae	186801|Clostridia	T	Signal transducing histidine kinase, homodimeric domain	cheA	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt,P2
k141_2611_7	639282.DEFDS_1712	7.18e-23	100.0	COG2204@1|root,COG2206@1|root,COG2204@2|Bacteria,COG2206@2|Bacteria,2GETM@200930|Deferribacteres	200930|Deferribacteres	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	HD_5,Response_reg
k141_2611_8	311424.DhcVS_887	5.76e-21	94.4	COG2202@1|root,COG2204@1|root,COG4191@1|root,COG2202@2|Bacteria,COG2204@2|Bacteria,COG4191@2|Bacteria,2G7Y4@200795|Chloroflexi,34CNC@301297|Dehalococcoidia	301297|Dehalococcoidia	T	PFAM ATP-binding region ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_9,Response_reg
k141_2930_2	1348635.BBJY01000010_gene1428	5.61e-40	144.0	COG1823@1|root,COG1823@2|Bacteria,1R3F8@1224|Proteobacteria,1RMHV@1236|Gammaproteobacteria,1XUK9@135623|Vibrionales	135623|Vibrionales	U	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family	-	-	-	ko:K06956	-	-	-	-	ko00000	-	-	-	SDF
k141_4029_1	498211.CJA_2520	6.07e-180	589.0	COG1022@1|root,COG5184@1|root,COG5276@1|root,COG1022@2|Bacteria,COG5184@2|Bacteria,COG5276@2|Bacteria,1PG4J@1224|Proteobacteria,1RWXR@1236|Gammaproteobacteria,1FIEH@10|Cellvibrio	1236|Gammaproteobacteria	DZ	Regulator of chromosome condensation (RCC1) repeat	-	-	-	-	-	-	-	-	-	-	-	-	RCC1
k141_2612_1	717772.THIAE_04360	1.78e-49	165.0	COG0463@1|root,COG0463@2|Bacteria,1RGMI@1224|Proteobacteria,1S525@1236|Gammaproteobacteria,4618G@72273|Thiotrichales	72273|Thiotrichales	M	transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
k141_2612_2	1121939.L861_02570	8.04e-39	146.0	COG2244@1|root,COG2244@2|Bacteria,1R9I0@1224|Proteobacteria,1RP3V@1236|Gammaproteobacteria,1XMCY@135619|Oceanospirillales	135619|Oceanospirillales	S	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt_3,Polysacc_synt_C
k141_2377_2	273057.SSO1218	1.27e-38	143.0	COG1012@1|root,arCOG01252@2157|Archaea,2XRV5@28889|Crenarchaeota	28889|Crenarchaeota	C	Aldehyde dehydrogenase family	-	-	1.2.1.18,1.2.1.27	ko:K00140	ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200	M00013	R00705,R00706,R00922,R00935	RC00004,RC02723,RC02817	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
k141_5015_2	1280698.AUJS01000079_gene3247	6.54e-28	120.0	COG0584@1|root,COG0584@2|Bacteria,1V3W4@1239|Firmicutes,24AVJ@186801|Clostridia,27W35@189330|Dorea	186801|Clostridia	C	Glycerophosphoryl diester phosphodiesterase family	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
k141_4741_1	684719.HIMB114_00006310	1.07e-36	134.0	COG1989@1|root,COG1989@2|Bacteria,1MUZF@1224|Proteobacteria,2UAW0@28211|Alphaproteobacteria,4BQZK@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	NOU	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue	gspO	-	3.4.23.43	ko:K02654	-	M00331	-	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	3.A.15.2	-	-	DiS_P_DiS,Peptidase_A24
k141_4741_2	1121405.dsmv_2119	0.0	1047.0	COG0466@1|root,COG0466@2|Bacteria,1MUV2@1224|Proteobacteria,42M9W@68525|delta/epsilon subdivisions,2WJ29@28221|Deltaproteobacteria,2MIDR@213118|Desulfobacterales	28221|Deltaproteobacteria	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon-3	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
k141_2027_1	1304885.AUEY01000001_gene3282	3.18e-219	612.0	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,42M0D@68525|delta/epsilon subdivisions,2WK8T@28221|Deltaproteobacteria,2MJ65@213118|Desulfobacterales	28221|Deltaproteobacteria	I	Belongs to the thiolase family	-	-	2.3.1.16	ko:K00632	ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212	M00087,M00113	R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955	ko00000,ko00001,ko00002,ko01000	-	-	-	Thiolase_C,Thiolase_N
k141_2027_2	1304885.AUEY01000001_gene3283	0.0	1127.0	COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,42MI5@68525|delta/epsilon subdivisions,2WITQ@28221|Deltaproteobacteria,2MI9V@213118|Desulfobacterales	28221|Deltaproteobacteria	I	3-hydroxyacyl-CoA dehydrogenase	-	-	1.1.1.35	ko:K07516	ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212	M00087	R01975,R04737,R04739,R04741,R04743,R04745,R04748,R05305	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000	-	-	-	3HCDH,3HCDH_N,ECH_1,ECH_2
k141_2027_4	999141.GME_13570	1.41e-38	138.0	COG0629@1|root,COG0629@2|Bacteria,1RCWT@1224|Proteobacteria,1S3WP@1236|Gammaproteobacteria,1XJHS@135619|Oceanospirillales	135619|Oceanospirillales	L	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism	ssb	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
k141_2027_5	1304885.AUEY01000025_gene2746	1.27e-153	459.0	COG1283@1|root,COG1283@2|Bacteria,1MUDE@1224|Proteobacteria,42PW9@68525|delta/epsilon subdivisions,2WJTI@28221|Deltaproteobacteria,2MJ12@213118|Desulfobacterales	28221|Deltaproteobacteria	P	PFAM Na Pi-cotransporter	-	-	-	ko:K03324	-	-	-	-	ko00000,ko02000	2.A.58.2	-	-	Na_Pi_cotrans,PhoU
k141_2027_6	868864.Dester_1397	1.76e-11	69.3	COG0116@1|root,COG0116@2|Bacteria,2G4FN@200783|Aquificae	200783|Aquificae	L	THUMP domain	-	-	-	ko:K07444	-	-	-	-	ko00000,ko01000	-	-	-	THUMP,UPF0020
k141_2084_2	96561.Dole_1236	1.93e-27	107.0	2EV1P@1|root,33NGS@2|Bacteria,1NNNK@1224|Proteobacteria,42Y1H@68525|delta/epsilon subdivisions,2WSVJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_3499_1	1307759.JOMJ01000003_gene1486	1.09e-127	377.0	COG0753@1|root,COG0753@2|Bacteria,1MUXZ@1224|Proteobacteria,42MIN@68525|delta/epsilon subdivisions,2WJC5@28221|Deltaproteobacteria,2M91H@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	Belongs to the catalase family	katA	-	1.11.1.6	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	M00532	R00009,R00602,R02670	RC00034,RC00767,RC02141,RC02755	ko00000,ko00001,ko00002,ko01000	-	-	-	Catalase,Catalase-rel
k141_2085_1	1232683.ADIMK_4100	9.87e-150	425.0	COG2227@1|root,COG2227@2|Bacteria,1R67Q@1224|Proteobacteria,1RVWP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	H	Methyltransferase type 12	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_12,Methyltransf_25,Methyltransf_31
k141_435_1	525897.Dbac_0604	2.39e-74	229.0	COG0500@1|root,COG0500@2|Bacteria,1QXX1@1224|Proteobacteria,43CRG@68525|delta/epsilon subdivisions,2X7Z5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	PFAM Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
k141_435_2	1121324.CLIT_8c00190	1.03e-61	202.0	COG0350@1|root,COG4912@1|root,COG0350@2|Bacteria,COG4912@2|Bacteria,1TQII@1239|Firmicutes,248N8@186801|Clostridia,25RFD@186804|Peptostreptococcaceae	186801|Clostridia	L	DNA alkylation repair enzyme	-	-	-	-	-	-	-	-	-	-	-	-	DNA_alkylation
k141_435_3	1056512.D515_01770	2.01e-33	120.0	COG1670@1|root,COG1670@2|Bacteria,1RCX2@1224|Proteobacteria,1S42B@1236|Gammaproteobacteria,1XXAE@135623|Vibrionales	135623|Vibrionales	J	COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
k141_4473_2	243277.VC_2020	1.47e-39	133.0	COG0236@1|root,COG0236@2|Bacteria,1MZ4P@1224|Proteobacteria,1S8X4@1236|Gammaproteobacteria,1XYA4@135623|Vibrionales	135623|Vibrionales	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
k141_4473_3	1348635.BBJY01000007_gene104	1.37e-147	419.0	COG1028@1|root,COG1028@2|Bacteria,1MU6X@1224|Proteobacteria,1RMBB@1236|Gammaproteobacteria,1XSFH@135623|Vibrionales	135623|Vibrionales	IQ	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	fabG	GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
k141_4473_4	223926.28807048	1.42e-183	514.0	COG0331@1|root,COG0331@2|Bacteria,1MV6N@1224|Proteobacteria,1RNH3@1236|Gammaproteobacteria,1XTJB@135623|Vibrionales	135623|Vibrionales	I	COG0331 (acyl-carrier-protein) S-malonyltransferase	fabD	-	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
k141_1439_1	1232437.KL662074_gene1755	3.16e-15	82.0	COG0438@1|root,COG0438@2|Bacteria,1R564@1224|Proteobacteria,42RYD@68525|delta/epsilon subdivisions,2X5EZ@28221|Deltaproteobacteria,2MP18@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Glycosyl transferase 4-like	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
k141_467_1	573370.DMR_39620	2.44e-09	63.9	COG0642@1|root,COG2199@1|root,COG2205@2|Bacteria,COG3706@2|Bacteria,1NRP8@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HWE_HK,HisKA,HisKA_2,PAS,PAS_3,PAS_4,PAS_9,Response_reg
k141_1791_1	1121403.AUCV01000037_gene4262	9.61e-233	666.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42PUU@68525|delta/epsilon subdivisions,2WKGS@28221|Deltaproteobacteria,2MPUZ@213118|Desulfobacterales	28221|Deltaproteobacteria	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal,dCache_1
k141_3794_1	29486.NJ56_15455	1.15e-42	144.0	COG1762@1|root,COG1762@2|Bacteria,1RDN9@1224|Proteobacteria,1S4GP@1236|Gammaproteobacteria,41FPZ@629|Yersinia	1236|Gammaproteobacteria	G	Phosphotransferase enzyme II, A component	cmtB	-	2.7.1.194	ko:K02821	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	M00283,M00550	R07671	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.7.1	-	-	PTS_EIIA_2
k141_3510_1	313589.JNB_06744	4.16e-17	85.9	COG3391@1|root,COG3391@2|Bacteria,2IE3F@201174|Actinobacteria	201174|Actinobacteria	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_468_1	1454004.AW11_03619	9.71e-31	120.0	COG0598@1|root,COG0598@2|Bacteria,1MW8W@1224|Proteobacteria,2W9IP@28216|Betaproteobacteria,1KR4K@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	P	CorA-like Mg2+ transporter protein	-	-	-	ko:K16074	-	-	-	-	ko00000,ko02000	1.A.35.4	-	-	CorA
k141_3511_2	522306.CAP2UW1_1341	3.29e-33	127.0	COG0845@1|root,COG0845@2|Bacteria,1MUI8@1224|Proteobacteria,2VNI0@28216|Betaproteobacteria	28216|Betaproteobacteria	M	HlyD membrane-fusion protein of T1SS	-	-	-	ko:K02022	-	-	-	-	ko00000	-	-	-	HlyD,HlyD_3
k141_3142_1	1121024.AUCD01000066_gene684	5.57e-51	169.0	COG2110@1|root,COG2110@2|Bacteria,1TPCU@1239|Firmicutes,4HIHC@91061|Bacilli,27I1J@186828|Carnobacteriaceae	91061|Bacilli	S	Appr-1'-p processing enzyme	ymdB	-	-	-	-	-	-	-	-	-	-	-	Macro
k141_3796_1	1121403.AUCV01000005_gene362	2.48e-91	285.0	COG0554@1|root,COG0554@2|Bacteria,1MUP7@1224|Proteobacteria,42M9Z@68525|delta/epsilon subdivisions,2WIYZ@28221|Deltaproteobacteria,2MIGS@213118|Desulfobacterales	1224|Proteobacteria	C	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate	glpK_1	-	2.7.1.30	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	-	R00847	RC00002,RC00017	ko00000,ko00001,ko01000,ko04147	-	-	-	FGGY_C,FGGY_N
k141_1792_3	345073.VC395_0657	1.09e-41	140.0	COG1314@1|root,COG1314@2|Bacteria,1N8MF@1224|Proteobacteria,1SD3P@1236|Gammaproteobacteria,1XXUA@135623|Vibrionales	135623|Vibrionales	U	Preprotein translocase subunit SecG	secG	-	-	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecG
k141_4825_2	104623.Ser39006_01384	2.3e-50	174.0	COG2014@1|root,COG2014@2|Bacteria,1NFAE@1224|Proteobacteria	1224|Proteobacteria	S	Putative heavy-metal chelation	-	-	-	-	-	-	-	-	-	-	-	-	DUF364
k141_4825_3	96561.Dole_0185	9.02e-43	152.0	COG2014@1|root,COG2014@2|Bacteria,1RGNW@1224|Proteobacteria,42RPF@68525|delta/epsilon subdivisions,2WNJQ@28221|Deltaproteobacteria,2MM2G@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Putative heavy-metal chelation	-	-	-	ko:K09138	-	-	-	-	ko00000	-	-	-	DUF364,DUF4213
k141_159_2	929703.KE386491_gene737	9.27e-10	63.2	COG0664@1|root,COG0664@2|Bacteria,4NMU0@976|Bacteroidetes,47R3C@768503|Cytophagia	976|Bacteroidetes	T	Cyclic nucleotide-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
k141_159_3	290397.Adeh_1030	7.16e-43	149.0	COG1335@1|root,COG1335@2|Bacteria,1MV0W@1224|Proteobacteria,42ZI3@68525|delta/epsilon subdivisions	1224|Proteobacteria	Q	Isochorismatase family	-	-	3.5.1.110	ko:K09020	ko00240,ko01100,map00240,map01100	-	R09947,R09980	RC02737,RC02738	ko00000,ko00001,ko01000	-	-	-	Isochorismatase,SnoaL_2
k141_159_4	1124991.MU9_2341	2e-51	187.0	COG0068@1|root,COG0068@2|Bacteria,1MVP8@1224|Proteobacteria,1RP08@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide	hypF	GO:0003674,GO:0003824,GO:0005488,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009987,GO:0010467,GO:0016740,GO:0016741,GO:0016743,GO:0019538,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0046872,GO:0046914,GO:0046944,GO:0051604,GO:0071704,GO:1901564	-	ko:K04656	-	-	-	-	ko00000	-	-	-	Acylphosphatase,Sua5_yciO_yrdC,zf-HYPF
k141_469_1	290402.Cbei_2233	7.29e-43	168.0	COG0840@1|root,COG0840@2|Bacteria,1TP5A@1239|Firmicutes,247S3@186801|Clostridia,36EG9@31979|Clostridiaceae	186801|Clostridia	NT	chemotaxis	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal,dCache_1
k141_161_1	1540257.JQMW01000005_gene249	2.21e-57	189.0	COG3843@1|root,COG3843@2|Bacteria,1TPRX@1239|Firmicutes,2481D@186801|Clostridia,36E9W@31979|Clostridiaceae	186801|Clostridia	U	Relaxase/Mobilisation nuclease domain	-	-	-	ko:K07126	-	-	-	-	ko00000	-	-	-	Relaxase
k141_3798_1	358681.BBR47_02840	1.62e-155	446.0	COG0584@1|root,COG0584@2|Bacteria,1UY23@1239|Firmicutes,4HEAD@91061|Bacilli	91061|Bacilli	C	glycerophosphoryl diester phosphodiesterase	glpQ	-	3.1.3.1,3.1.4.46	ko:K01113,ko:K01126	ko00564,ko00790,ko01100,ko02020,map00564,map00790,map01100,map02020	M00126	R01030,R01470,R04620	RC00017,RC00425	ko00000,ko00001,ko00002,ko01000	-	-	-	GDPD
k141_4486_1	1238450.VIBNISOn1_1910022	3.66e-75	230.0	COG0663@1|root,COG0663@2|Bacteria,1RD76@1224|Proteobacteria,1RPB6@1236|Gammaproteobacteria,1XU2T@135623|Vibrionales	135623|Vibrionales	S	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily	yrdA	-	-	-	-	-	-	-	-	-	-	-	Hexapep
k141_4486_2	701176.VIBRN418_13116	2.89e-31	112.0	2E6QS@1|root,331AY@2|Bacteria,1N7X6@1224|Proteobacteria,1SC8J@1236|Gammaproteobacteria,1XYV9@135623|Vibrionales	135623|Vibrionales	S	Protein of unknown function (DUF1488)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1488
k141_4486_3	55601.VANGNB10_cI0065	2.62e-143	410.0	COG0169@1|root,COG0169@2|Bacteria,1MVH4@1224|Proteobacteria,1RPB7@1236|Gammaproteobacteria,1XTNJ@135623|Vibrionales	135623|Vibrionales	E	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	aroE	GO:0000166,GO:0003674,GO:0003824,GO:0004764,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	-	Shikimate_DH,Shikimate_dh_N
k141_470_1	439235.Dalk_0084	6.52e-33	130.0	COG0784@1|root,COG2202@1|root,COG4191@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42M1R@68525|delta/epsilon subdivisions,2X734@28221|Deltaproteobacteria,2MIC0@213118|Desulfobacterales	28221|Deltaproteobacteria	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CheB_methylest,CheR,CheR_N,GAF,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
k141_470_2	1232410.KI421418_gene2118	4.46e-84	270.0	COG2838@1|root,COG2838@2|Bacteria,1MV6Q@1224|Proteobacteria,42MY0@68525|delta/epsilon subdivisions,2WM7X@28221|Deltaproteobacteria,43SYK@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Monomeric isocitrate dehydrogenase	icd	-	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	IDH
k141_162_1	933262.AXAM01000003_gene2868	4.55e-69	226.0	COG0635@1|root,COG0635@2|Bacteria,1MU76@1224|Proteobacteria,42NGU@68525|delta/epsilon subdivisions,2WIM5@28221|Deltaproteobacteria,2MI7T@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Involved in the biosynthesis of porphyrin-containing compound	-	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
k141_4488_2	984262.SGRA_3004	6.17e-14	75.1	COG0535@1|root,COG0535@2|Bacteria,4NGWY@976|Bacteroidetes,1IWI9@117747|Sphingobacteriia	976|Bacteroidetes	C	Radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM,SPASM
k141_4827_2	1120963.KB894494_gene3439	1.12e-153	437.0	COG2084@1|root,COG2084@2|Bacteria,1MUGU@1224|Proteobacteria,1RQ2D@1236|Gammaproteobacteria,2PZWU@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	I	COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases	garR	-	1.1.1.31,1.1.1.60	ko:K00020,ko:K00042	ko00280,ko00630,ko01100,map00280,map00630,map01100	-	R01745,R01747,R05066	RC00099	ko00000,ko00001,ko01000	-	-	-	NAD_binding_11,NAD_binding_2
k141_4827_3	1001530.BACE01000011_gene2260	7.39e-25	103.0	COG1167@1|root,COG1167@2|Bacteria,1MUJE@1224|Proteobacteria,1RXYA@1236|Gammaproteobacteria,1XVSK@135623|Vibrionales	135623|Vibrionales	K	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2,GntR
k141_1440_2	13035.Dacsa_0857	4.67e-12	78.6	COG2834@1|root,COG3210@1|root,COG2834@2|Bacteria,COG3210@2|Bacteria	2|Bacteria	U	domain, Protein	-	-	-	ko:K03634	-	-	-	-	ko00000	-	-	-	CHU_C,Cadherin,Calx-beta,DUF5122,Haemagg_act,HemolysinCabind,PPC,VCBS
k141_471_1	1304885.AUEY01000004_gene974	1.08e-143	420.0	COG1960@1|root,COG1960@2|Bacteria,1R15B@1224|Proteobacteria,42MUT@68525|delta/epsilon subdivisions,2WJ8T@28221|Deltaproteobacteria,2MI3E@213118|Desulfobacterales	28221|Deltaproteobacteria	C	acyl-CoA dehydrogenase	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M
k141_471_2	933262.AXAM01000053_gene2716	6.53e-60	196.0	COG1355@1|root,COG1355@2|Bacteria,1MXK5@1224|Proteobacteria,42R55@68525|delta/epsilon subdivisions,2WKKG@28221|Deltaproteobacteria,2MJ1F@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Memo-like protein	-	-	-	ko:K06990	-	-	-	-	ko00000,ko04812	-	-	-	Memo
k141_2424_1	1236959.BAMT01000007_gene2729	2.78e-70	257.0	COG0715@1|root,COG5001@1|root,COG0715@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,2KMBP@206350|Nitrosomonadales	206350|Nitrosomonadales	T	PFAM EAL domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF,NMT1,PAS_3,PAS_9
k141_2424_2	675815.VOA_001981	5.18e-42	144.0	COG3637@1|root,COG3637@2|Bacteria,1RHVI@1224|Proteobacteria,1S6UY@1236|Gammaproteobacteria,1XVZ1@135623|Vibrionales	135623|Vibrionales	M	OmpA-like transmembrane domain	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl
k141_2424_3	675815.VOA_001749	2.06e-64	203.0	COG0671@1|root,COG0671@2|Bacteria,1N3TP@1224|Proteobacteria,1SADV@1236|Gammaproteobacteria,1Y2AB@135623|Vibrionales	135623|Vibrionales	I	Acid phosphatase homologues	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
k141_2424_4	493475.GARC_0315	9.53e-47	158.0	COG0745@1|root,COG0745@2|Bacteria,1MU67@1224|Proteobacteria,1RR2T@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Transcriptional regulatory protein, C terminal	copR	-	-	ko:K07665	ko02020,map02020	M00452,M00745	-	-	ko00000,ko00001,ko00002,ko01504,ko02022	-	-	-	Response_reg,Trans_reg_C
k141_3144_1	338969.Rfer_0691	4.29e-15	78.2	COG2244@1|root,COG2244@2|Bacteria,1MUMD@1224|Proteobacteria,2WEWR@28216|Betaproteobacteria,4AJNX@80864|Comamonadaceae	28216|Betaproteobacteria	S	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt_3,Polysacc_synt_C
k141_3144_2	396595.TK90_0313	0.000277	51.2	COG0438@1|root,COG0438@2|Bacteria,1QEP7@1224|Proteobacteria,1RZIT@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	glycosyl transferase group 1	wabK	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
k141_3144_3	290317.Cpha266_1821	7.32e-31	123.0	COG1442@1|root,COG1442@2|Bacteria	2|Bacteria	M	lipopolysaccharide 3-alpha-galactosyltransferase activity	gspA	GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0016051,GO:0016740,GO:0016757,GO:0043170,GO:0044238,GO:0071704,GO:1901576	-	-	-	-	-	-	-	-	-	-	Glyco_transf_8
k141_4490_1	767817.Desgi_4171	1.37e-16	80.5	COG0840@1|root,COG0840@2|Bacteria,1TP5A@1239|Firmicutes,247S3@186801|Clostridia,260AA@186807|Peptococcaceae	186801|Clostridia	NT	Methyl-accepting chemotaxis protein (MCP) signaling domain	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal,dCache_1,dCache_3
k141_472_1	272562.CA_C2493	7.79e-36	134.0	2DV8B@1|root,33UMF@2|Bacteria	2|Bacteria	S	Zinc dependent phospholipase C	-	-	-	-	-	-	-	-	-	-	-	-	Zn_dep_PLPC
k141_166_1	1121434.AULY01000008_gene213	1.24e-137	398.0	COG1902@1|root,COG1902@2|Bacteria,1MVE0@1224|Proteobacteria,42NA7@68525|delta/epsilon subdivisions,2WIN5@28221|Deltaproteobacteria,2M8DT@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	PFAM NADH flavin oxidoreductase NADH oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_FMN
k141_4491_2	1443125.Z962_06970	6.13e-35	131.0	COG0357@1|root,COG0357@2|Bacteria,1TPBT@1239|Firmicutes,247WM@186801|Clostridia,36EMZ@31979|Clostridiaceae	186801|Clostridia	J	Specifically methylates the N7 position of a guanine in 16S rRNA	rsmG	-	2.1.1.170	ko:K03501	-	-	-	-	ko00000,ko01000,ko03009,ko03036	-	-	-	GidB
k141_2425_2	1278309.KB907103_gene1180	6.52e-37	127.0	COG4899@1|root,COG4899@2|Bacteria,1N9UQ@1224|Proteobacteria,1SW54@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Uncharacterized protein conserved in bacteria (DUF2199)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2199
k141_3145_1	332101.JIBU02000003_gene4515	3.63e-74	233.0	COG1052@1|root,COG1052@2|Bacteria,1TPCX@1239|Firmicutes,248UR@186801|Clostridia,36UMS@31979|Clostridiaceae	186801|Clostridia	CH	D-isomer specific 2-hydroxyacid dehydrogenase	-	-	1.1.1.215,1.1.1.399,1.1.1.79,1.1.1.81,1.1.1.95	ko:K00058,ko:K00090	ko00030,ko00260,ko00620,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00260,map00620,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00020	R00465,R01388,R01392,R01513,R01739	RC00031,RC00042,RC00084	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
k141_4492_1	1484157.PSNIH2_04180	1.57e-08	55.5	COG4215@1|root,COG4215@2|Bacteria,1MY2N@1224|Proteobacteria,1RNYD@1236|Gammaproteobacteria,3VYKJ@53335|Pantoea	1236|Gammaproteobacteria	P	amino acid ABC transporter	hisQ	GO:0003333,GO:0003674,GO:0005215,GO:0005287,GO:0005290,GO:0005291,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006855,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015174,GO:0015179,GO:0015238,GO:0015318,GO:0015711,GO:0015802,GO:0015807,GO:0015849,GO:0015893,GO:0016020,GO:0022857,GO:0034220,GO:0042221,GO:0042493,GO:0043090,GO:0044464,GO:0045117,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0089709,GO:0089718,GO:0098655,GO:0098656,GO:0098657,GO:0098739,GO:1901474,GO:1902475,GO:1903810,GO:1903825,GO:1905039,GO:1990822	-	ko:K10016,ko:K10024	ko02010,map02010	M00225,M00226,M00235	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3.1,3.A.1.3.11	-	iSbBS512_1146.SbBS512_E2686	BPD_transp_1
k141_167_2	323850.Shew_0251	5.17e-45	150.0	COG0582@1|root,COG0582@2|Bacteria,1P1R9@1224|Proteobacteria,1RRV0@1236|Gammaproteobacteria,2QBF5@267890|Shewanellaceae	1236|Gammaproteobacteria	L	PFAM phage integrase family protein	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
k141_1441_2	675813.VIB_000166	8.1e-37	127.0	COG2963@1|root,COG2963@2|Bacteria,1NGD6@1224|Proteobacteria,1SGJ8@1236|Gammaproteobacteria,1XY4H@135623|Vibrionales	135623|Vibrionales	L	Transposase ISVa5 (IS66-family	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_1441_3	323850.Shew_3836	2.93e-67	205.0	COG3436@1|root,COG3436@2|Bacteria,1MZFT@1224|Proteobacteria,1SABV@1236|Gammaproteobacteria,2QDVJ@267890|Shewanellaceae	1236|Gammaproteobacteria	L	IS66 Orf2 like protein	-	-	-	ko:K07484	-	-	-	-	ko00000	-	-	-	TnpB_IS66
k141_1441_4	675813.VIB_000170	8.37e-40	143.0	COG3316@1|root,COG3316@2|Bacteria,1RHKZ@1224|Proteobacteria,1S7XK@1236|Gammaproteobacteria,1Y33H@135623|Vibrionales	135623|Vibrionales	L	Transposase IS66 family	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS66,LZ_Tnp_IS66,zf-IS66
k141_3799_2	1005999.GLGR_0046	1.26e-108	375.0	COG2373@1|root,COG2373@2|Bacteria,1MV7J@1224|Proteobacteria,1RNRY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	Large extracellular alpha-helical protein	-	-	-	ko:K06894	-	-	-	-	ko00000	-	-	-	A2M,A2M_N,A2M_N_2,MG1,Thiol-ester_cl
k141_4493_1	406818.XBJ1_0784	0.000249	45.8	COG1463@1|root,COG3008@1|root,COG1463@2|Bacteria,COG3008@2|Bacteria,1MU1T@1224|Proteobacteria,1RN89@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	paraquat-inducible protein b	pqiB	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006810,GO:0006869,GO:0008150,GO:0009987,GO:0010876,GO:0016043,GO:0030288,GO:0030313,GO:0031975,GO:0033036,GO:0042597,GO:0042802,GO:0044464,GO:0051179,GO:0051234,GO:0061024,GO:0071702,GO:0071840,GO:0120009	-	ko:K06192	-	-	-	-	ko00000	-	-	-	MlaD
k141_3800_1	644282.Deba_2504	4.31e-78	238.0	COG1584@1|root,COG1584@2|Bacteria,1N4S7@1224|Proteobacteria,42TRC@68525|delta/epsilon subdivisions,2WR3R@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	GPR1/FUN34/yaaH family	-	-	-	ko:K07034	-	-	-	-	ko00000	-	-	-	Grp1_Fun34_YaaH
k141_3800_2	96561.Dole_2500	1.45e-34	129.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,42MK5@68525|delta/epsilon subdivisions,2WJ3Z@28221|Deltaproteobacteria,2MI0N@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM Acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
k141_473_2	933262.AXAM01000085_gene1058	3.79e-165	482.0	COG1159@1|root,COG1159@2|Bacteria,1QW17@1224|Proteobacteria,42MZH@68525|delta/epsilon subdivisions,2WKAE@28221|Deltaproteobacteria,2MHS2@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF3482)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3482,MMR_HSR1
k141_473_3	1304885.AUEY01000005_gene793	3.52e-16	84.7	2C6CZ@1|root,32R7W@2|Bacteria,1RH5F@1224|Proteobacteria,42NQC@68525|delta/epsilon subdivisions,2WMFH@28221|Deltaproteobacteria,2MIVU@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF2868)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2868
k141_5145_1	1033737.CAEV01000098_gene1736	2.25e-241	692.0	COG3829@1|root,COG3829@2|Bacteria,1TP0E@1239|Firmicutes,247MB@186801|Clostridia,36DY7@31979|Clostridiaceae	186801|Clostridia	KT	PFAM sigma-54 factor interaction domain-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,PAS,PAS_9,Sigma54_activat
k141_5145_2	293826.Amet_0592	8.76e-153	438.0	COG2515@1|root,COG2515@2|Bacteria,1UDCW@1239|Firmicutes,24BXZ@186801|Clostridia,36GV4@31979|Clostridiaceae	186801|Clostridia	E	Pyridoxal-phosphate dependent enzyme	-	-	4.4.1.15	ko:K05396	ko00270,map00270	-	R01874	RC00382	ko00000,ko00001,ko01000	-	-	-	PALP
k141_5145_3	1304866.K413DRAFT_3281	4.11e-214	599.0	COG1168@1|root,COG1168@2|Bacteria,1TP5G@1239|Firmicutes,248AY@186801|Clostridia,36DKQ@31979|Clostridiaceae	186801|Clostridia	E	PFAM Aminotransferase class I and II	patB	-	4.4.1.8	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	-	R00782,R01286,R02408,R04941	RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
k141_5145_4	457421.CBFG_03027	2.43e-225	629.0	COG1301@1|root,COG1301@2|Bacteria,1TQ3F@1239|Firmicutes,25CGZ@186801|Clostridia,26AP7@186813|unclassified Clostridiales	186801|Clostridia	U	Sodium:dicarboxylate symporter family	-	-	-	-	-	-	-	-	-	-	-	-	SDF
k141_5145_5	1121289.JHVL01000011_gene1398	1.76e-25	114.0	COG0747@1|root,COG0747@2|Bacteria	2|Bacteria	E	dipeptide transport	dppA	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	C5-epim_C,SBP_bac_5
k141_5145_7	394503.Ccel_0901	4.64e-07	58.2	COG3858@1|root,COG3858@2|Bacteria,1UJN3@1239|Firmicutes,25F62@186801|Clostridia,36UXG@31979|Clostridiaceae	186801|Clostridia	S	PFAM copper amine oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Cu_amine_oxidN1
k141_5145_8	632245.CLP_3857	5.62e-240	697.0	COG2217@1|root,COG2217@2|Bacteria,1TQ07@1239|Firmicutes,248EH@186801|Clostridia,36DXT@31979|Clostridiaceae	186801|Clostridia	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	cadA	-	3.6.3.3,3.6.3.5	ko:K01534	-	-	-	-	ko00000,ko01000	3.A.3.6	-	-	E1-E2_ATPase,HMA,Hydrolase
k141_4494_1	335659.S23_30980	4.39e-16	77.8	2CDHC@1|root,30KXA@2|Bacteria,1PT2N@1224|Proteobacteria,2UANN@28211|Alphaproteobacteria,3K6B4@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_1547_2	439235.Dalk_2563	2.87e-242	676.0	COG3303@1|root,COG3303@2|Bacteria,1P8CP@1224|Proteobacteria,42MXS@68525|delta/epsilon subdivisions,2WKEK@28221|Deltaproteobacteria,2MI5R@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Seven times multi-haem cytochrome CxxCH	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554,Multi-haem_cyto
k141_1547_3	882.DVU_2013	3.34e-108	331.0	COG0369@1|root,COG1151@2|Bacteria,1N88B@1224|Proteobacteria,42M2C@68525|delta/epsilon subdivisions,2WIVE@28221|Deltaproteobacteria,2MAAI@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O	hcp	GO:0000302,GO:0003674,GO:0003824,GO:0004601,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016661,GO:0016684,GO:0042221,GO:0042493,GO:0042542,GO:0046677,GO:0050418,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1901700,GO:1990748	1.7.99.1	ko:K05601	ko00910,map00910	-	R00143	RC02797	ko00000,ko00001,ko01000	-	-	iAF987.Gmet_2834	Prismane
k141_2255_1	672.VV93_v1c31200	4.74e-53	176.0	2CJ6B@1|root,32S9B@2|Bacteria,1N2I4@1224|Proteobacteria,1S8Z8@1236|Gammaproteobacteria,1XWS0@135623|Vibrionales	135623|Vibrionales	S	Thermostable hemolysin	-	-	-	-	-	-	-	-	-	-	-	-	T_hemolysin
k141_2255_2	1116375.VEJY3_08015	1.98e-132	400.0	COG1022@1|root,COG1022@2|Bacteria,1MU4D@1224|Proteobacteria,1RPNE@1236|Gammaproteobacteria,1XSHH@135623|Vibrionales	135623|Vibrionales	I	AMP-binding enzyme	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding
k141_2255_3	675806.VII_000312	2.79e-99	294.0	COG1022@1|root,COG1022@2|Bacteria,1QV90@1224|Proteobacteria,1T2AG@1236|Gammaproteobacteria,1XVNZ@135623|Vibrionales	135623|Vibrionales	I	Iron-containing redox enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Haem_oxygenas_2
k141_2255_4	1219065.VPR01S_11_01530	7.16e-95	287.0	COG0300@1|root,COG0300@2|Bacteria,1RAFB@1224|Proteobacteria,1S2HE@1236|Gammaproteobacteria,1XVH5@135623|Vibrionales	135623|Vibrionales	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
k141_2255_5	1348635.BBJY01000001_gene2622	1.28e-99	294.0	COG3063@1|root,COG3063@2|Bacteria,1RD9T@1224|Proteobacteria,1S3R3@1236|Gammaproteobacteria,1XX1A@135623|Vibrionales	135623|Vibrionales	NU	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_19,TPR_8
k141_2255_6	29495.EA26_08940	1.69e-108	317.0	COG0745@1|root,COG0745@2|Bacteria,1N0YI@1224|Proteobacteria,1RQQ3@1236|Gammaproteobacteria,1XUKM@135623|Vibrionales	135623|Vibrionales	K	Transcriptional regulatory protein, C terminal	-	-	-	ko:K02483,ko:K07666	ko02020,ko02024,map02020,map02024	M00453	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
k141_2255_7	1348635.BBJY01000001_gene2624	8.12e-178	513.0	COG0642@1|root,COG2205@2|Bacteria,1N1Z2@1224|Proteobacteria,1RPG9@1236|Gammaproteobacteria,1XV7G@135623|Vibrionales	135623|Vibrionales	T	His Kinase A (phosphoacceptor) domain	-	-	2.7.13.3	ko:K07645	ko02020,ko02024,map02020,map02024	M00453	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	2CSK_N,HATPase_c,HisKA
k141_2255_8	243277.VC_A0829	4.05e-82	272.0	COG0365@1|root,COG0365@2|Bacteria,1MUX7@1224|Proteobacteria,1RPGT@1236|Gammaproteobacteria,1XVRA@135623|Vibrionales	135623|Vibrionales	I	COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases	acs-2	-	6.2.1.16	ko:K01907	ko00280,ko00650,map00280,map00650	-	R01357	RC00004,RC00014	ko00000,ko00001,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
k141_3229_1	1278307.KB906975_gene1921	2.1e-49	187.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,2QIQ4@267894|Psychromonadaceae	1236|Gammaproteobacteria	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K03406,ko:K05875	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal,TarH,dCache_1
k141_832_1	1232443.BAIA02000159_gene1705	3.87e-25	105.0	COG0457@1|root,COG4859@1|root,COG0457@2|Bacteria,COG4859@2|Bacteria,1TT4Q@1239|Firmicutes,24847@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF2185,DUF4253,DUF4261,DUF4375,SUFU,SUKH_6,TPR_2
k141_4649_1	945550.VISI1226_12321	1.92e-110	318.0	COG0450@1|root,COG0450@2|Bacteria,1MWPY@1224|Proteobacteria,1RN4S@1236|Gammaproteobacteria,1XUVP@135623|Vibrionales	135623|Vibrionales	O	Alkyl hydroperoxide reductase	ahpC	-	1.11.1.15	ko:K03386	ko04214,map04214	-	-	-	ko00000,ko00001,ko01000,ko04147	-	-	-	1-cysPrx_C,AhpC-TSA
k141_4649_2	1219065.VPR01S_11_00670	9.04e-122	362.0	COG3634@1|root,COG3634@2|Bacteria,1MUKD@1224|Proteobacteria,1RNC7@1236|Gammaproteobacteria,1XT7A@135623|Vibrionales	135623|Vibrionales	O	COG3634 Alkyl hydroperoxide reductase, large subunit	ahpF	-	-	ko:K03387	-	-	-	-	ko00000,ko01000	-	-	-	Pyr_redox_2,Thioredoxin_3
k141_2258_1	177437.HRM2_30670	1.3e-36	137.0	2DBU2@1|root,2ZB3S@2|Bacteria,1N1MT@1224|Proteobacteria,42VJX@68525|delta/epsilon subdivisions,2WSPP@28221|Deltaproteobacteria,2MNKM@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_4
k141_1548_1	933262.AXAM01000011_gene1751	1.59e-269	760.0	COG0205@1|root,COG0205@2|Bacteria,1R560@1224|Proteobacteria,42P6N@68525|delta/epsilon subdivisions,2WINA@28221|Deltaproteobacteria,2MHN0@213118|Desulfobacterales	28221|Deltaproteobacteria	G	Phosphofructokinase	pfp	-	2.7.1.11,2.7.1.90	ko:K00895,ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
k141_3627_1	1304885.AUEY01000039_gene1545	2.44e-206	581.0	COG0055@1|root,COG0055@2|Bacteria,1MUFU@1224|Proteobacteria,42KZA@68525|delta/epsilon subdivisions,2WJ1V@28221|Deltaproteobacteria,2MI99@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
k141_3627_2	439235.Dalk_3627	4.61e-115	340.0	COG0224@1|root,COG0224@2|Bacteria,1MU28@1224|Proteobacteria,42N8B@68525|delta/epsilon subdivisions,2WJ6I@28221|Deltaproteobacteria,2MIR3@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	-	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
k141_3627_3	1304885.AUEY01000039_gene1543	1.29e-208	588.0	COG0056@1|root,COG0056@2|Bacteria,1MUG7@1224|Proteobacteria,42MVX@68525|delta/epsilon subdivisions,2WIK7@28221|Deltaproteobacteria,2MIHR@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
k141_2259_2	1121451.DESAM_22655	5.12e-30	113.0	2FIJ8@1|root,34ABA@2|Bacteria,1NDU3@1224|Proteobacteria,42VPH@68525|delta/epsilon subdivisions,2WS81@28221|Deltaproteobacteria,2MCBI@213115|Desulfovibrionales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_2259_3	713587.THITH_08665	2.53e-08	57.0	COG3864@1|root,COG3864@2|Bacteria,1MY13@1224|Proteobacteria,1RXX2@1236|Gammaproteobacteria,1WX24@135613|Chromatiales	135613|Chromatiales	S	VWA-like domain (DUF2201)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2201,DUF2201_N
k141_1549_1	1265505.ATUG01000002_gene1298	1.64e-32	116.0	COG0824@1|root,COG0824@2|Bacteria,1N8J9@1224|Proteobacteria	1224|Proteobacteria	S	Thioesterase-like superfamily	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT,4HBT_2
k141_1549_3	626939.HMPREF9443_01229	5.28e-08	54.7	COG0111@1|root,COG0111@2|Bacteria,1V410@1239|Firmicutes,4H2KQ@909932|Negativicutes	909932|Negativicutes	E	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family	serA	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C,ACT
k141_839_2	1227352.C173_08651	5.51e-45	154.0	COG0327@1|root,COG0327@2|Bacteria,1URBZ@1239|Firmicutes,4HMCN@91061|Bacilli,275FW@186822|Paenibacillaceae	91061|Bacilli	S	NIF3 (NGG1p interacting factor 3)	-	-	-	-	-	-	-	-	-	-	-	-	NIF3
k141_4258_2	1304885.AUEY01000008_gene2072	2.25e-65	202.0	COG0698@1|root,COG0698@2|Bacteria,1RHBF@1224|Proteobacteria,42SAN@68525|delta/epsilon subdivisions,2WP1V@28221|Deltaproteobacteria,2MJX4@213118|Desulfobacterales	28221|Deltaproteobacteria	G	ribose 5-phosphate isomerase B	rpiB	-	5.3.1.6	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01056,R09030	RC00376,RC00434	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1604	LacAB_rpiB
k141_4258_3	1304885.AUEY01000008_gene2073	3.09e-208	586.0	COG0112@1|root,COG0112@2|Bacteria,1MUIS@1224|Proteobacteria,42M0T@68525|delta/epsilon subdivisions,2WJ3C@28221|Deltaproteobacteria,2MHY8@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
k141_4258_4	398767.Glov_1747	1.24e-70	216.0	COG2131@1|root,COG2131@2|Bacteria,1RD1P@1224|Proteobacteria,42RHI@68525|delta/epsilon subdivisions,2WNGV@28221|Deltaproteobacteria,43U1G@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	PFAM CMP dCMP deaminase zinc-binding	comEB	-	3.5.4.12	ko:K01493	ko00240,ko01100,map00240,map01100	M00429	R01663	RC00074	ko00000,ko00001,ko00002,ko01000,ko02044	-	-	-	dCMP_cyt_deam_1
k141_4258_5	96561.Dole_2080	2.61e-64	200.0	COG1327@1|root,COG1327@2|Bacteria,1RE7V@1224|Proteobacteria,42SJP@68525|delta/epsilon subdivisions,2WPK0@28221|Deltaproteobacteria,2MJT3@213118|Desulfobacterales	28221|Deltaproteobacteria	K	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes	nrdR	-	-	ko:K07738	-	-	-	-	ko00000,ko03000	-	-	-	ATP-cone
k141_4258_6	96561.Dole_2079	5.75e-113	341.0	COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,1MUWT@1224|Proteobacteria,42NBS@68525|delta/epsilon subdivisions,2WIP2@28221|Deltaproteobacteria,2MIE9@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate	ribD	-	1.1.1.193,3.5.4.26	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1624	RibD_C,dCMP_cyt_deam_1
k141_4258_7	1304885.AUEY01000008_gene2077	1.21e-87	265.0	COG0307@1|root,COG0307@2|Bacteria,1MUMB@1224|Proteobacteria,42QT1@68525|delta/epsilon subdivisions,2WNK6@28221|Deltaproteobacteria,2MJM4@213118|Desulfobacterales	28221|Deltaproteobacteria	H	TIGRFAM riboflavin synthase, alpha subunit	ribE	-	2.5.1.9	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00066	RC00958,RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	Lum_binding
k141_4258_8	96561.Dole_2077	2.09e-210	590.0	COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,1MU8P@1224|Proteobacteria,42N1C@68525|delta/epsilon subdivisions,2WIP5@28221|Deltaproteobacteria,2MIF1@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	ribBA	-	3.5.4.25,4.1.99.12	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	DHBP_synthase,GTP_cyclohydro2
k141_4258_9	1265505.ATUG01000002_gene2597	4.64e-71	218.0	COG0054@1|root,COG0054@2|Bacteria,1RD9J@1224|Proteobacteria,42RQ6@68525|delta/epsilon subdivisions,2WNCZ@28221|Deltaproteobacteria,2MJXP@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin	ribH	GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.78	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R04457	RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	DMRL_synthase
k141_4258_10	933262.AXAM01000019_gene1104	1.63e-47	157.0	COG0781@1|root,COG0781@2|Bacteria,1N94P@1224|Proteobacteria,42SEA@68525|delta/epsilon subdivisions,2WQP9@28221|Deltaproteobacteria,2MK59@213118|Desulfobacterales	28221|Deltaproteobacteria	K	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons	nusB	-	-	ko:K03625	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusB
k141_4258_11	1304885.AUEY01000008_gene2082	1.68e-94	283.0	COG0491@1|root,COG0491@2|Bacteria,1MUDN@1224|Proteobacteria,42QWD@68525|delta/epsilon subdivisions,2WN14@28221|Deltaproteobacteria,2MJKK@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Metallo-beta-lactamase superfamily	ycbL	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
k141_4258_12	717231.Flexsi_2297	3.63e-71	240.0	COG4623@1|root,COG4623@2|Bacteria	2|Bacteria	M	carbon-oxygen lyase activity, acting on polysaccharides	mltF	GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0008150,GO:0008152,GO:0008933,GO:0009056,GO:0009057,GO:0009253,GO:0009279,GO:0016020,GO:0016740,GO:0016757,GO:0019867,GO:0030203,GO:0030312,GO:0030313,GO:0031975,GO:0043170,GO:0044462,GO:0044464,GO:0061783,GO:0071704,GO:0071944,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575	-	ko:K18691	-	-	-	-	ko00000,ko01000,ko01011	-	-	iBWG_1329.BWG_2322,iEC042_1314.EC042_2762,iECDH1ME8569_1439.ECDH1ME8569_2485,iECNA114_1301.ECNA114_2631,iECP_1309.ECP_2560,iECSF_1327.ECSF_2397,iECW_1372.ECW_m2786,iEKO11_1354.EKO11_1175,iEcDH1_1363.EcDH1_1110,iEcHS_1320.EcHS_A2711,iEcolC_1368.EcolC_1119,iG2583_1286.G2583_3089,iJO1366.b2558,iSFxv_1172.SFxv_2861,iUMN146_1321.UM146_03930,iUMNK88_1353.UMNK88_3212,iUTI89_1310.UTI89_C2878,iWFL_1372.ECW_m2786,iY75_1357.Y75_RS13345	SBP_bac_3,SLT
k141_4258_13	457396.CSBG_01766	2.73e-42	148.0	COG0821@1|root,COG0821@2|Bacteria,1TPFR@1239|Firmicutes,247N1@186801|Clostridia,36DRW@31979|Clostridiaceae	186801|Clostridia	I	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate	ispG	-	1.17.7.1,1.17.7.3	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R08689,R10859	RC01486	ko00000,ko00001,ko00002,ko01000	-	-	-	GcpE
k141_3628_1	1322246.BN4_20341	1.13e-70	229.0	COG1696@1|root,COG1696@2|Bacteria,1MUXN@1224|Proteobacteria,42MIR@68525|delta/epsilon subdivisions,2WMEK@28221|Deltaproteobacteria,2MGH0@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	PFAM membrane bound O-acyl transferase MBOAT	algI	-	-	ko:K19294	-	-	-	-	ko00000	-	-	-	MBOAT
k141_1263_1	1108045.GORHZ_092_00050	1.28e-14	73.9	COG0147@1|root,COG0147@2|Bacteria,2GQA1@201174|Actinobacteria,4GCZF@85026|Gordoniaceae	201174|Actinobacteria	EH	chorismate binding enzyme	-	-	4.2.99.21,5.4.4.2	ko:K04781	ko01053,ko01110,ko01130,map01053,map01110,map01130	-	R06602	RC01549,RC02148	ko00000,ko00001,ko01000	-	-	-	Chorismate_bind
k141_1263_2	489825.LYNGBM3L_74510	4.07e-146	495.0	COG1020@1|root,COG3321@1|root,COG1020@2|Bacteria,COG3321@2|Bacteria,1FZXE@1117|Cyanobacteria,1H927@1150|Oscillatoriales	1117|Cyanobacteria	Q	Acyl transferase domain in polyketide synthase (PKS) enzymes.	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,AMP-binding,AMP-binding_C,Acyl_transf_1,Condensation,ECH_1,KAsynt_C_assoc,Ketoacyl-synt_C,PP-binding,Thioesterase,ketoacyl-synt
k141_300_1	1304885.AUEY01000010_gene1640	0.0	919.0	COG1960@1|root,COG1960@2|Bacteria,1MU20@1224|Proteobacteria,42MUH@68525|delta/epsilon subdivisions,2WJ16@28221|Deltaproteobacteria,2MJ7S@213118|Desulfobacterales	28221|Deltaproteobacteria	I	acyl-CoA dehydrogenase	-	-	-	ko:K09456	-	-	-	-	ko00000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_C,Acyl-CoA_dh_M,Acyl-CoA_dh_N,AcylCoA_DH_N
k141_300_2	96561.Dole_1417	3.29e-284	798.0	COG0247@1|root,COG0247@2|Bacteria,1MUMH@1224|Proteobacteria,42MIV@68525|delta/epsilon subdivisions,2WJ5X@28221|Deltaproteobacteria,2MIC5@213118|Desulfobacterales	28221|Deltaproteobacteria	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_8,Fer4_9
k141_3247_1	522306.CAP2UW1_4331	1.48e-46	155.0	COG2050@1|root,COG2050@2|Bacteria,1RGVP@1224|Proteobacteria,2VVH4@28216|Betaproteobacteria	28216|Betaproteobacteria	Q	Thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
k141_3247_2	1144275.COCOR_00895	1.69e-10	64.3	COG1846@1|root,COG1846@2|Bacteria,1N1RV@1224|Proteobacteria,42WMS@68525|delta/epsilon subdivisions,2WR99@28221|Deltaproteobacteria,2Z2BS@29|Myxococcales	28221|Deltaproteobacteria	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR
k141_3655_2	1125863.JAFN01000001_gene722	5.43e-19	82.0	COG2257@1|root,COG2257@2|Bacteria,1N7F1@1224|Proteobacteria,42VB5@68525|delta/epsilon subdivisions,2WRJD@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM FlhB HrpN YscU SpaS Family	-	-	-	ko:K04061	-	-	-	-	ko00000,ko02044	-	-	-	Bac_export_2
k141_3655_3	177437.HRM2_37030	1.86e-73	229.0	COG4786@1|root,COG4786@2|Bacteria,1PZ24@1224|Proteobacteria,42NGI@68525|delta/epsilon subdivisions,2WMR8@28221|Deltaproteobacteria,2MJP8@213118|Desulfobacterales	28221|Deltaproteobacteria	N	basal body rod protein	flgF	-	-	ko:K02391,ko:K02392	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod,Flg_bbr_C
k141_3655_4	177437.HRM2_37020	8.04e-139	397.0	COG4786@1|root,COG4786@2|Bacteria,1MVMA@1224|Proteobacteria,42N3R@68525|delta/epsilon subdivisions,2WJDN@28221|Deltaproteobacteria,2MIW5@213118|Desulfobacterales	28221|Deltaproteobacteria	N	flagellar basal-body rod protein FlgG	flgG	-	-	ko:K02392	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod,Flg_bbr_C
k141_849_1	204669.Acid345_1272	4.81e-108	326.0	COG0430@1|root,COG0430@2|Bacteria	2|Bacteria	A	RNA-3'-phosphate cyclase activity	rtcA	GO:0003674,GO:0003824,GO:0003963,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009975,GO:0016874,GO:0016886,GO:0044424,GO:0044464,GO:0140098	6.5.1.4	ko:K01974	-	-	-	-	ko00000,ko01000	-	-	-	RTC,RTC_insert
k141_4656_1	1524467.IV04_00070	2.17e-107	318.0	28H7K@1|root,2Z7JT@2|Bacteria,1MV01@1224|Proteobacteria,1RSNP@1236|Gammaproteobacteria,400XB@613|Serratia	1236|Gammaproteobacteria	U	The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system	kdgT	-	-	ko:K02526	-	-	-	-	ko00000,ko02000	2.A.10.1	-	-	KdgT
k141_323_1	1517681.HW45_21575	7.12e-246	680.0	COG0282@1|root,COG0282@2|Bacteria,1MW61@1224|Proteobacteria,1RMKB@1236|Gammaproteobacteria,1XSVG@135623|Vibrionales	135623|Vibrionales	F	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction	ackA1	GO:0003674,GO:0003824,GO:0006091,GO:0006113,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008776,GO:0009987,GO:0015980,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0044237,GO:0055114	2.7.2.1	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00315,R01353	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetate_kinase
k141_323_2	1348635.BBJY01000004_gene2956	0.0	1248.0	COG0280@1|root,COG0857@1|root,COG0280@2|Bacteria,COG0857@2|Bacteria,1QTS5@1224|Proteobacteria,1RMJS@1236|Gammaproteobacteria,1XT1N@135623|Vibrionales	135623|Vibrionales	C	belongs to the CobB CobQ family	pta	GO:0003674,GO:0003824,GO:0006091,GO:0006113,GO:0008150,GO:0008152,GO:0008959,GO:0009987,GO:0015980,GO:0016407,GO:0016740,GO:0016746,GO:0016747,GO:0044237,GO:0055114	2.3.1.8	ko:K13788	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00230,R00921	RC00004,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_26,DRTGG,PTA_PTB
k141_323_3	675806.VII_002691	9.45e-53	174.0	COG0435@1|root,COG0435@2|Bacteria,1MV50@1224|Proteobacteria,1RMTI@1236|Gammaproteobacteria,1XSAM@135623|Vibrionales	135623|Vibrionales	O	Glutathione S-transferase	-	-	1.8.5.7	ko:K07393	-	-	-	-	ko00000,ko01000	-	-	-	GST_C_2,GST_N_2
k141_2289_1	1122176.KB903609_gene5244	2.6e-23	105.0	COG1305@1|root,COG1305@2|Bacteria,4NI22@976|Bacteroidetes,1INVZ@117747|Sphingobacteriia	976|Bacteroidetes	E	Transglutaminase-like	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_2851_1	159087.Daro_0007	2.95e-15	75.9	COG3437@1|root,COG3437@2|Bacteria,1MUB8@1224|Proteobacteria,2VH1F@28216|Betaproteobacteria,2KUSD@206389|Rhodocyclales	206389|Rhodocyclales	KT	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	ko:K07814	-	-	-	-	ko00000,ko02022	-	-	-	HD,Response_reg
k141_2851_2	177437.HRM2_33390	3.87e-107	322.0	COG3437@1|root,COG3437@2|Bacteria,1MUB8@1224|Proteobacteria,42QB7@68525|delta/epsilon subdivisions,2WM6Y@28221|Deltaproteobacteria,2MHYS@213118|Desulfobacterales	28221|Deltaproteobacteria	T	metal-dependent phosphohydrolase HD region	-	-	-	ko:K07814	-	-	-	-	ko00000,ko02022	-	-	-	HD,HD_5,Response_reg
k141_2851_3	879212.DespoDRAFT_00120	1.35e-22	93.6	COG1321@1|root,COG1321@2|Bacteria,1RHIK@1224|Proteobacteria,42SAD@68525|delta/epsilon subdivisions,2WPIC@28221|Deltaproteobacteria,2MKI7@213118|Desulfobacterales	28221|Deltaproteobacteria	K	PFAM iron dependent repressor	-	-	-	ko:K03709	-	-	-	-	ko00000,ko03000	-	-	-	Fe_dep_repr_C,Fe_dep_repress,FeoA
k141_2528_2	55601.VANGNB10_cI2503	0.0	948.0	COG1086@1|root,COG1086@2|Bacteria,1MWKY@1224|Proteobacteria,1RNQ2@1236|Gammaproteobacteria,1XUT0@135623|Vibrionales	135623|Vibrionales	GM	nucleoside-diphosphate sugar epimerases	-	-	-	-	-	-	-	-	-	-	-	-	CoA_binding_3,Polysacc_synt_2
k141_2528_3	579405.Dd703_3272	1.14e-101	309.0	COG0451@1|root,COG0451@2|Bacteria,1MX2J@1224|Proteobacteria,1RPHW@1236|Gammaproteobacteria,2JDAZ@204037|Dickeya	1236|Gammaproteobacteria	M	PFAM NAD-dependent epimerase dehydratase	wbpV	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
k141_2528_4	298386.PBPRA2697	3.2e-90	268.0	COG2148@1|root,COG2148@2|Bacteria,1R4J5@1224|Proteobacteria,1RP9R@1236|Gammaproteobacteria,1XT9C@135623|Vibrionales	135623|Vibrionales	M	COG2148 Sugar transferases involved in lipopolysaccharide synthesis	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf
k141_2528_5	1187848.AJYQ01000004_gene199	1.42e-136	397.0	COG0608@1|root,COG0608@2|Bacteria,1N37P@1224|Proteobacteria,1RQTR@1236|Gammaproteobacteria,1XTYY@135623|Vibrionales	135623|Vibrionales	L	single-stranded DNA 5'-3' exodeoxyribonuclease activity	-	-	-	-	-	-	-	-	-	-	-	-	DHHA1
k141_2528_6	1116375.VEJY3_01050	1.19e-223	630.0	COG1109@1|root,COG1109@2|Bacteria,1MUB3@1224|Proteobacteria,1RNFZ@1236|Gammaproteobacteria,1XSPD@135623|Vibrionales	135623|Vibrionales	G	Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III	-	-	5.4.2.8	ko:K01840	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01818	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
k141_2528_7	1116375.VEJY3_01155	7.52e-251	697.0	COG0836@1|root,COG0836@2|Bacteria,1MV39@1224|Proteobacteria,1RNQI@1236|Gammaproteobacteria,1XUKR@135623|Vibrionales	135623|Vibrionales	M	Belongs to the mannose-6-phosphate isomerase type 2 family	rfbA	GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0008150,GO:0008152,GO:0008905,GO:0008928,GO:0009058,GO:0009059,GO:0016051,GO:0016740,GO:0016757,GO:0016772,GO:0016779,GO:0043170,GO:0044238,GO:0070568,GO:0071704,GO:1901576	2.7.7.13	ko:K00971	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	M00114,M00361,M00362	R00885	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	MannoseP_isomer,NTP_transferase
k141_2528_8	312309.VF_0166	1.07e-218	608.0	COG1088@1|root,COG1088@2|Bacteria,1MU5E@1224|Proteobacteria,1RP7G@1236|Gammaproteobacteria,1XUQ1@135623|Vibrionales	135623|Vibrionales	M	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily	-	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
k141_2528_9	55601.VANGNB10_cI2482c	1.13e-209	592.0	COG1236@1|root,COG1236@2|Bacteria,1MUDD@1224|Proteobacteria,1RPZC@1236|Gammaproteobacteria,1XUP7@135623|Vibrionales	135623|Vibrionales	J	exonuclease of the beta-lactamase fold involved in RNA processing	-	-	-	ko:K07576	-	-	-	-	ko00000	-	-	-	Beta-Casp,Lactamase_B,RMMBL
k141_2528_10	55601.VANGNB10_cI2478c	9.38e-104	303.0	COG3068@1|root,COG3068@2|Bacteria,1MWSN@1224|Proteobacteria,1RQDG@1236|Gammaproteobacteria,1XT50@135623|Vibrionales	135623|Vibrionales	S	protein conserved in bacteria	yjaG	-	-	ko:K09891	-	-	-	-	ko00000	-	-	-	DUF416
k141_2528_11	55601.VANGNB10_cI2479	1.59e-129	378.0	COG0111@1|root,COG0111@2|Bacteria,1MW1U@1224|Proteobacteria,1RRQE@1236|Gammaproteobacteria,1XT3B@135623|Vibrionales	135623|Vibrionales	EH	COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases	-	-	-	-	-	-	-	-	-	-	-	-	2-Hacid_dh_C
k141_2528_12	675814.VIC_004981	2.93e-104	305.0	COG1573@1|root,COG1573@2|Bacteria,1R9XV@1224|Proteobacteria,1S20R@1236|Gammaproteobacteria,1XVHC@135623|Vibrionales	135623|Vibrionales	L	COG1573 Uracil-DNA glycosylase	-	-	-	-	-	-	-	-	-	-	-	-	UDG
k141_2528_13	1219065.VPR01S_26_00040	7.4e-170	484.0	COG1253@1|root,COG1253@2|Bacteria,1MWT3@1224|Proteobacteria,1RQBC@1236|Gammaproteobacteria,1XT75@135623|Vibrionales	135623|Vibrionales	S	COG1253 Hemolysins and related proteins containing CBS domains	-	-	-	-	-	-	-	-	-	-	-	-	CBS,DUF21
k141_2528_14	29495.EA26_20415	2.39e-49	157.0	COG0776@1|root,COG0776@2|Bacteria,1MZ5B@1224|Proteobacteria,1S8VH@1236|Gammaproteobacteria,1XXVI@135623|Vibrionales	135623|Vibrionales	L	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions	hupA	GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005694,GO:0005737,GO:0005829,GO:0006323,GO:0006996,GO:0008150,GO:0009889,GO:0009987,GO:0010556,GO:0016043,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0051276,GO:0060255,GO:0065007,GO:0071103,GO:0071840,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2001141	-	ko:K05787	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
k141_2528_15	1348635.BBJY01000026_gene2301	1.37e-82	253.0	28HWS@1|root,2Z82N@2|Bacteria,1QFI0@1224|Proteobacteria,1RPY5@1236|Gammaproteobacteria,1XTX1@135623|Vibrionales	135623|Vibrionales	M	Protein of unknown function (DUF1481)	atpB	-	-	-	-	-	-	-	-	-	-	-	DUF1481
k141_2528_16	1191299.AJYX01000038_gene3374	1.15e-155	443.0	COG1281@1|root,COG1281@2|Bacteria,1MUMU@1224|Proteobacteria,1RMP3@1236|Gammaproteobacteria,1XTZA@135623|Vibrionales	135623|Vibrionales	O	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress	hslO	-	-	ko:K04083	-	-	-	-	ko00000,ko03110	-	-	-	HSP33
k141_2528_17	1517681.HW45_00505	3.52e-71	216.0	COG1188@1|root,COG1188@2|Bacteria,1MZR6@1224|Proteobacteria,1S8VU@1236|Gammaproteobacteria,1XXB2@135623|Vibrionales	135623|Vibrionales	J	implicated in the recycling of the	hslR	-	-	ko:K04762	-	-	-	-	ko00000,ko03110	-	-	-	S4
k141_2528_18	1348635.BBJY01000009_gene1460	4.98e-61	203.0	COG3031@1|root,COG3031@2|Bacteria,1RD3I@1224|Proteobacteria,1RQKA@1236|Gammaproteobacteria,1XU1I@135623|Vibrionales	135623|Vibrionales	U	general secretion pathway protein	epsC	GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705	-	ko:K02452	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSC
k141_2528_19	1348635.BBJY01000009_gene1461	0.0	981.0	COG1450@1|root,COG1450@2|Bacteria,1MUUA@1224|Proteobacteria,1RPJS@1236|Gammaproteobacteria,1XSIA@135623|Vibrionales	135623|Vibrionales	NU	General secretion pathway protein	gspD	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	Secretin,Secretin_N
k141_2528_20	55601.VANGNB10_cI0156	4.56e-261	726.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,1RMBS@1236|Gammaproteobacteria,1XTS6@135623|Vibrionales	135623|Vibrionales	NU	COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB	epsE	-	-	ko:K02454	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSE
k141_2528_21	345073.VC395_2843	3.64e-172	494.0	COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,1RQ86@1236|Gammaproteobacteria,1XTCY@135623|Vibrionales	135623|Vibrionales	U	general secretion pathway protein	epsF	GO:0002790,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015628,GO:0015833,GO:0016020,GO:0032940,GO:0033036,GO:0042886,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098776	-	ko:K02455	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSF
k141_2528_22	345073.VC395_2842	3.86e-81	242.0	COG2165@1|root,COG2165@2|Bacteria,1RDX2@1224|Proteobacteria,1S3VS@1236|Gammaproteobacteria,1XWYF@135623|Vibrionales	135623|Vibrionales	U	general secretion pathway protein	epsG	GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,T2SSG
k141_2528_23	675816.VIA_000586	2e-34	127.0	COG2165@1|root,COG2165@2|Bacteria,1N7HZ@1224|Proteobacteria,1SCWD@1236|Gammaproteobacteria,1XWQW@135623|Vibrionales	135623|Vibrionales	NU	COG2165 Type II secretory pathway, pseudopilin PulG	epsH	GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705	-	ko:K02457	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	GspH,N_methyl
k141_2528_24	1187848.AJYQ01000004_gene108	6.01e-26	101.0	COG2165@1|root,COG2165@2|Bacteria,1N737@1224|Proteobacteria,1SC8X@1236|Gammaproteobacteria,1XXW2@135623|Vibrionales	135623|Vibrionales	NU	COG2165 Type II secretory pathway, pseudopilin PulG	epsI	GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705	-	ko:K02458	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,T2SSI
k141_2528_25	1188252.AJYK01000120_gene971	1.79e-62	200.0	COG4795@1|root,COG4795@2|Bacteria,1RJAE@1224|Proteobacteria,1S5ZZ@1236|Gammaproteobacteria,1XU01@135623|Vibrionales	135623|Vibrionales	U	general secretion pathway protein	epsJ	GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015628,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0098776	-	ko:K02459	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,T2SSJ
k141_2528_26	945550.VISI1226_16478	3.79e-110	331.0	COG3156@1|root,COG3156@2|Bacteria,1RC9P@1224|Proteobacteria,1T072@1236|Gammaproteobacteria,1XT6W@135623|Vibrionales	135623|Vibrionales	U	COG3156 Type II secretory pathway, component PulK	epsK	-	-	ko:K02460	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSK
k141_2528_27	104623.Ser39006_03456	1.1e-40	156.0	COG3297@1|root,COG3297@2|Bacteria,1NVVW@1224|Proteobacteria,1S01F@1236|Gammaproteobacteria,402ZM@613|Serratia	1236|Gammaproteobacteria	U	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins	gspL	-	-	ko:K02461	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	GspL_C,T2SSL
k141_2528_28	675814.VIC_000123	4.68e-36	129.0	COG3149@1|root,COG3149@2|Bacteria,1N8VZ@1224|Proteobacteria,1S8X3@1236|Gammaproteobacteria,1XU6P@135623|Vibrionales	135623|Vibrionales	U	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins	epsM	GO:0008150,GO:0009405,GO:0044419,GO:0051704	-	ko:K02462	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSM
k141_2528_29	1056512.D515_02237	2.98e-35	133.0	2CBG9@1|root,32RTB@2|Bacteria,1R86M@1224|Proteobacteria,1RNNN@1236|Gammaproteobacteria,1XV6Z@135623|Vibrionales	135623|Vibrionales	S	Type II secretion system (T2SS), protein N	epsN	GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705	-	ko:K02463	ko05111,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSN
k141_2528_30	243277.VC_2722	3.47e-146	418.0	COG1218@1|root,COG1218@2|Bacteria,1N0GY@1224|Proteobacteria,1RP5A@1236|Gammaproteobacteria,1XUIT@135623|Vibrionales	135623|Vibrionales	P	COG1218 3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase	cysQ	-	3.1.3.7	ko:K01082	ko00920,ko01100,ko01120,ko01130,map00920,map01100,map01120,map01130	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03016	-	-	-	Inositol_P
k141_4392_102	536232.CLM_3034	1.57e-197	561.0	COG0165@1|root,COG0165@2|Bacteria,1TNZ6@1239|Firmicutes,2489H@186801|Clostridia,36E9J@31979|Clostridiaceae	186801|Clostridia	E	argininosuccinate lyase	argH	-	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ASL_C2,Lyase_1
k141_4392_103	1128398.Curi_c06880	2.28e-207	583.0	COG0137@1|root,COG0137@2|Bacteria,1TP3X@1239|Firmicutes,247MF@186801|Clostridia,26889@186813|unclassified Clostridiales	186801|Clostridia	E	Arginosuccinate synthase	argG	-	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Arginosuc_synth
k141_4392_104	1121324.CLIT_5c00170	7.91e-95	287.0	COG0834@1|root,COG0834@2|Bacteria,1TT16@1239|Firmicutes,24CEZ@186801|Clostridia,25REG@186804|Peptostreptococcaceae	186801|Clostridia	ET	Bacterial periplasmic substrate-binding proteins	artP	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
k141_4392_105	1215092.PA6_031_00600	9.27e-12	63.9	2DQZH@1|root,339IV@2|Bacteria,1NIT0@1224|Proteobacteria,1SI7G@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_4475_10	696281.Desru_3472	3.4e-08	65.5	COG0840@1|root,COG5278@1|root,COG0840@2|Bacteria,COG5278@2|Bacteria,1TP5A@1239|Firmicutes,247S3@186801|Clostridia,261XC@186807|Peptococcaceae	186801|Clostridia	NT	Methyl-accepting chemotaxis protein (MCP) signaling domain	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal
k141_4475_11	941824.TCEL_00112	5.69e-60	221.0	COG0840@1|root,COG0840@2|Bacteria,1TP5A@1239|Firmicutes,247S3@186801|Clostridia,36EQK@31979|Clostridiaceae	186801|Clostridia	NT	chemotaxis	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal,dCache_1,sCache_3_2
k141_4475_12	1121324.CLIT_10c00930	7.03e-76	240.0	COG0778@1|root,COG0778@2|Bacteria,1V297@1239|Firmicutes,24FWY@186801|Clostridia,25UIE@186804|Peptostreptococcaceae	186801|Clostridia	C	Putative TM nitroreductase	-	-	-	-	-	-	-	-	-	-	-	-	TM1586_NiRdase
k141_4475_13	1211817.CCAT010000062_gene3943	7.35e-196	556.0	COG2252@1|root,COG2252@2|Bacteria,1TQC6@1239|Firmicutes,2483Q@186801|Clostridia,36DY4@31979|Clostridiaceae	186801|Clostridia	S	Permease	-	-	-	ko:K06901	-	-	-	-	ko00000,ko02000	2.A.1.40	-	-	Xan_ur_permease
k141_4475_14	1444309.JAQG01000004_gene3590	6.02e-05	54.7	COG3858@1|root,COG3858@2|Bacteria,1UJQT@1239|Firmicutes,4ITDF@91061|Bacilli,277D3@186822|Paenibacillaceae	91061|Bacilli	S	S-layer homology domain	-	-	-	-	-	-	-	-	-	-	-	-	PepSY,SLH
k141_4475_15	645991.Sgly_2241	4.94e-48	160.0	COG0756@1|root,COG0756@2|Bacteria,1V6HX@1239|Firmicutes,24K3X@186801|Clostridia,2624W@186807|Peptococcaceae	186801|Clostridia	F	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA	dut	-	3.6.1.23	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	M00053	R02100,R11896	RC00002	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	dUTPase
k141_4475_16	1033733.CAEK01000001_gene217	6.56e-88	270.0	COG0348@1|root,COG0348@2|Bacteria,1TPHF@1239|Firmicutes,247KH@186801|Clostridia,22GGE@1570339|Peptoniphilaceae	186801|Clostridia	C	4Fe-4S binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_5
k141_4475_17	411459.RUMOBE_02065	2.87e-08	50.8	2AQUU@1|root,31G2Z@2|Bacteria,1UDXX@1239|Firmicutes,25IS7@186801|Clostridia,3Y251@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_4475_18	536227.CcarbDRAFT_4064	1.43e-62	202.0	COG0745@1|root,COG0745@2|Bacteria,1TRS2@1239|Firmicutes,24AF1@186801|Clostridia,36GSN@31979|Clostridiaceae	186801|Clostridia	T	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	gtcR	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
k141_4475_19	1121324.CLIT_10c02400	1.57e-49	180.0	COG5002@1|root,COG5002@2|Bacteria,1TPVJ@1239|Firmicutes,2489X@186801|Clostridia	186801|Clostridia	T	Histidine kinase- DNA gyrase B	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
k141_4475_20	1121324.CLIT_12c00140	1.75e-122	363.0	COG0392@1|root,COG0392@2|Bacteria,1TXG8@1239|Firmicutes,24A1A@186801|Clostridia,25UJG@186804|Peptostreptococcaceae	186801|Clostridia	I	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms	mprF	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
k141_4475_21	1121324.CLIT_12c00150	1.02e-124	371.0	COG0707@1|root,COG0707@2|Bacteria,1UQ6A@1239|Firmicutes,248FR@186801|Clostridia,25RD8@186804|Peptostreptococcaceae	186801|Clostridia	M	Monogalactosyldiacylglycerol synthase	-	-	2.4.1.315	ko:K03429	ko00561,ko01100,map00561,map01100	-	R02689,R04377	RC00005,RC00059	ko00000,ko00001,ko01000,ko01003	-	GT28	-	Glyco_tran_28_C,MGDG_synth
k141_4475_22	641107.CDLVIII_4238	1.2e-99	320.0	COG3829@1|root,COG3829@2|Bacteria,1TP0E@1239|Firmicutes,247MB@186801|Clostridia,36DY7@31979|Clostridiaceae	186801|Clostridia	KT	PFAM sigma-54 factor interaction domain-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	PAS,PAS_9,PTS-HPr,Sigma54_activat
k141_4475_23	1235790.C805_02469	1.08e-33	120.0	COG3862@1|root,COG3862@2|Bacteria,1VA4U@1239|Firmicutes,24MN9@186801|Clostridia,25WVW@186806|Eubacteriaceae	186801|Clostridia	S	Protein of unknown function (DUF1667)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1667
k141_4475_24	1347392.CCEZ01000007_gene1959	3.09e-205	578.0	COG0446@1|root,COG0446@2|Bacteria,1TQH5@1239|Firmicutes,247YR@186801|Clostridia,36DSF@31979|Clostridiaceae	186801|Clostridia	C	Oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Pyr_redox_3
k141_4475_25	1121289.JHVL01000017_gene764	1.01e-222	628.0	COG0579@1|root,COG0579@2|Bacteria,1TRDH@1239|Firmicutes,248IK@186801|Clostridia,36DNW@31979|Clostridiaceae	186801|Clostridia	C	FAD dependent oxidoreductase	glpA	-	1.1.5.3	ko:K00111	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	DAO,Fer2_BFD
k141_4475_26	1121289.JHVL01000017_gene763	4.23e-299	823.0	COG0554@1|root,COG0554@2|Bacteria,1TPX3@1239|Firmicutes,2493W@186801|Clostridia,36EMF@31979|Clostridiaceae	186801|Clostridia	F	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate	glpK	GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615	2.7.1.30	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	-	R00847	RC00002,RC00017	ko00000,ko00001,ko01000,ko04147	-	-	-	FGGY_C,FGGY_N
k141_4475_27	883081.HMPREF9698_00635	1.61e-23	94.4	2DMS0@1|root,32T9Q@2|Bacteria,1VCJ5@1239|Firmicutes,4HN6D@91061|Bacilli,27GUS@186828|Carnobacteriaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_4475_28	1209989.TepiRe1_0622	1.05e-47	156.0	2DMKJ@1|root,32S74@2|Bacteria,1VC4F@1239|Firmicutes,24SDE@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_4475_29	386415.NT01CX_0613	3.38e-65	205.0	COG1954@1|root,COG1954@2|Bacteria,1V4IE@1239|Firmicutes,24HDM@186801|Clostridia,36I0D@31979|Clostridiaceae	186801|Clostridia	K	glycerol-3-phosphate responsive antiterminator	glpP	-	-	ko:K02443	-	-	-	-	ko00000,ko03000	-	-	-	G3P_antiterm
k141_1078_1	1121405.dsmv_2249	1.15e-178	535.0	COG0308@1|root,COG0308@2|Bacteria,1MUCI@1224|Proteobacteria,42KZI@68525|delta/epsilon subdivisions,2WJ2C@28221|Deltaproteobacteria,2MIKQ@213118|Desulfobacterales	28221|Deltaproteobacteria	E	TIGRFAM aminopeptidase N	pepN	-	3.4.11.2	ko:K01256,ko:K08776	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	DUF3458,DUF3458_C,ERAP1_C,HEAT_2,Peptidase_M1
k141_459_1	220341.16504417	2.17e-167	473.0	COG1951@1|root,COG1951@2|Bacteria,1MW8J@1224|Proteobacteria,1RPUD@1236|Gammaproteobacteria,3ZJUS@590|Salmonella	1236|Gammaproteobacteria	C	Fumarate hydratase (Fumerase)	ttdA	GO:0008150,GO:0008152,GO:1901275	4.2.1.32	ko:K03779	ko00630,map00630	-	R00339	RC01382	ko00000,ko00001,ko01000	-	-	iLF82_1304.LF82_2330	Fumerase
k141_459_3	272563.CD630_28210	5.62e-37	136.0	COG3366@1|root,COG3366@2|Bacteria,1V1QK@1239|Firmicutes,24GN4@186801|Clostridia	186801|Clostridia	S	Nucleoside recognition	-	-	-	-	-	-	-	-	-	-	-	-	Gate
k141_459_4	298386.PBPRA2833	6.39e-71	221.0	COG1280@1|root,COG1280@2|Bacteria,1RDPB@1224|Proteobacteria,1S5JJ@1236|Gammaproteobacteria,1XTFX@135623|Vibrionales	135623|Vibrionales	E	threonine efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	LysE
k141_459_5	298386.PBPRA0112	1.6e-27	117.0	COG0583@1|root,COG0583@2|Bacteria,1N663@1224|Proteobacteria,1SN55@1236|Gammaproteobacteria,1XSZP@135623|Vibrionales	135623|Vibrionales	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
k141_2417_1	1304880.JAGB01000002_gene2041	2.18e-09	65.5	COG0747@1|root,COG0747@2|Bacteria,1TPPC@1239|Firmicutes,25CDQ@186801|Clostridia	186801|Clostridia	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
k141_2417_2	411902.CLOBOL_01675	1.07e-29	122.0	COG0601@1|root,COG0601@2|Bacteria,1TP1S@1239|Firmicutes,247IP@186801|Clostridia,2225A@1506553|Lachnoclostridium	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
k141_2417_3	318586.Pden_1610	6.42e-36	135.0	COG1173@1|root,COG1173@2|Bacteria,1RCDJ@1224|Proteobacteria,2U6JR@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
k141_2417_4	1471459.JFLJ01000060_gene1846	7.46e-23	105.0	COG1123@1|root,COG4172@2|Bacteria,1G1N3@1117|Cyanobacteria,1MKXN@1212|Prochloraceae	1117|Cyanobacteria	P	ATP binding component, possibly for oligopeptides	-	-	-	ko:K02031,ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
k141_1079_1	443143.GM18_1791	3.07e-52	175.0	COG0381@1|root,COG0381@2|Bacteria,1QUYI@1224|Proteobacteria,42MSY@68525|delta/epsilon subdivisions,2WJXR@28221|Deltaproteobacteria,43S9C@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Belongs to the UDP-N-acetylglucosamine 2-epimerase family	-	-	5.1.3.14	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	M00362	R00420	RC00290	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase_2
k141_1079_2	1121405.dsmv_0709	1.66e-74	230.0	COG1922@1|root,COG1922@2|Bacteria,1N1HD@1224|Proteobacteria,42TWK@68525|delta/epsilon subdivisions,2WQSK@28221|Deltaproteobacteria,2MPR7@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Glycosyl transferase WecB/TagA/CpsF family	-	-	2.4.1.187	ko:K05946	ko05111,map05111	-	-	-	ko00000,ko00001,ko01000,ko01003	-	GT26	-	Glyco_tran_WecB
k141_1784_1	1116375.VEJY3_18341	1.63e-44	152.0	COG0583@1|root,COG0583@2|Bacteria,1NUAB@1224|Proteobacteria,1RNYQ@1236|Gammaproteobacteria,1XSF5@135623|Vibrionales	1236|Gammaproteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
k141_1784_3	675813.VIB_001186	1.98e-76	236.0	COG4565@1|root,COG4565@2|Bacteria,1RKMA@1224|Proteobacteria,1S70V@1236|Gammaproteobacteria,1XSB3@135623|Vibrionales	135623|Vibrionales	K	transcriptional regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
k141_1784_4	675813.VIB_001187	5.58e-222	630.0	COG3290@1|root,COG3290@2|Bacteria,1MXQ5@1224|Proteobacteria,1RNRF@1236|Gammaproteobacteria,1XSAU@135623|Vibrionales	1236|Gammaproteobacteria	T	COG3290 Signal transduction histidine kinase regulating citrate malate metabolism	dcuS	GO:0000155,GO:0000160,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006355,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0016020,GO:0016021,GO:0016043,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0018106,GO:0018193,GO:0018202,GO:0019219,GO:0019222,GO:0019538,GO:0022607,GO:0023014,GO:0023052,GO:0031224,GO:0031226,GO:0031323,GO:0031326,GO:0035556,GO:0036211,GO:0042802,GO:0043170,GO:0043412,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0051259,GO:0051260,GO:0051716,GO:0060255,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:0071944,GO:0080090,GO:0140096,GO:1901564,GO:1903506,GO:2000112,GO:2001141	2.7.13.3	ko:K02476,ko:K07701,ko:K11614	ko02020,map02020	M00488,M00490	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,PAS,SPOB_a,sCache_3_2
k141_1784_6	1248232.BANQ01000045_gene3360	2.17e-59	185.0	COG3080@1|root,COG3080@2|Bacteria,1RDZD@1224|Proteobacteria,1S3W5@1236|Gammaproteobacteria,1XXAW@135623|Vibrionales	135623|Vibrionales	C	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane	frdD	GO:0000104,GO:0003674,GO:0003824,GO:0006091,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015980,GO:0016491,GO:0016627,GO:0044237,GO:0045333,GO:0055114	-	ko:K00247	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	M00009,M00011,M00150,M00173	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	Fumarate_red_D
k141_1784_7	1219080.VEZ01S_45_00140	1.6e-62	194.0	COG3029@1|root,COG3029@2|Bacteria,1MZ4C@1224|Proteobacteria,1SC0P@1236|Gammaproteobacteria,1XXFQ@135623|Vibrionales	135623|Vibrionales	C	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane	frdC	GO:0000104,GO:0003674,GO:0003824,GO:0006091,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015980,GO:0016491,GO:0016627,GO:0044237,GO:0045333,GO:0055114	-	ko:K00246	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	M00009,M00011,M00150,M00173	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	Fumarate_red_C
k141_1784_10	55601.VANGNB10_cI2405c	1.71e-157	449.0	COG2269@1|root,COG2269@2|Bacteria,1MU97@1224|Proteobacteria,1RMR9@1236|Gammaproteobacteria,1XSYN@135623|Vibrionales	135623|Vibrionales	J	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P	epmA	GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006430,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576	-	ko:K04568	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	tRNA-synt_2
k141_1784_11	1116375.VEJY3_14415	1.04e-66	206.0	COG0607@1|root,COG0607@2|Bacteria,1MZ83@1224|Proteobacteria,1S8ZI@1236|Gammaproteobacteria,1XWWT@135623|Vibrionales	135623|Vibrionales	P	rhodanese-related sulfurtransferase	yibN	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
k141_4813_1	1515746.HR45_01565	8.55e-188	535.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,1RQ36@1236|Gammaproteobacteria,2QAKM@267890|Shewanellaceae	1236|Gammaproteobacteria	L	Belongs to the DEAD box helicase family	dbpA	GO:0000027,GO:0000166,GO:0003674,GO:0003676,GO:0003723,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0006996,GO:0008026,GO:0008144,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0033677,GO:0034458,GO:0034459,GO:0034622,GO:0034641,GO:0035639,GO:0036094,GO:0042254,GO:0042255,GO:0042273,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0043531,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0065003,GO:0070035,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:0097367,GO:0140097,GO:0140098,GO:1901265,GO:1901360,GO:1901363	3.6.4.13	ko:K05591	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	DEAD,DbpA,Helicase_C
k141_4813_4	1348635.BBJY01000008_gene1715	2.29e-309	857.0	COG0025@1|root,COG1226@1|root,COG0025@2|Bacteria,COG1226@2|Bacteria,1QTUE@1224|Proteobacteria,1T1HJ@1236|Gammaproteobacteria,1XUJX@135623|Vibrionales	135623|Vibrionales	P	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger,TrkA_N
k141_4813_5	484770.UFO1_3862	5.13e-54	173.0	COG0537@1|root,COG0537@2|Bacteria,1V3BE@1239|Firmicutes,4H891@909932|Negativicutes	909932|Negativicutes	FG	HIT domain	-	-	-	-	-	-	-	-	-	-	-	-	HIT
k141_4813_6	55601.VANGNB10_cI1329c	4.21e-103	303.0	COG1280@1|root,COG1280@2|Bacteria,1RF1D@1224|Proteobacteria,1T02Q@1236|Gammaproteobacteria,1XUXV@135623|Vibrionales	135623|Vibrionales	E	LysE type translocator	-	-	-	-	-	-	-	-	-	-	-	-	LysE
k141_1080_1	485916.Dtox_3435	4.52e-57	194.0	COG1964@1|root,COG1964@2|Bacteria,1TVES@1239|Firmicutes,248NC@186801|Clostridia,260FE@186807|Peptococcaceae	186801|Clostridia	C	PFAM Radical SAM	-	-	-	ko:K06937	-	-	-	-	ko00000,ko01000	-	-	-	Fer4_12,Fer4_14,Radical_SAM
k141_5133_3	1304885.AUEY01000042_gene3601	2.07e-202	571.0	COG0438@1|root,COG0438@2|Bacteria,1N9EV@1224|Proteobacteria,42PK2@68525|delta/epsilon subdivisions,2WJS7@28221|Deltaproteobacteria,2MIWA@213118|Desulfobacterales	28221|Deltaproteobacteria	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
k141_1785_1	96561.Dole_2494	6.15e-66	209.0	COG0548@1|root,COG0548@2|Bacteria,1MU17@1224|Proteobacteria,42N8G@68525|delta/epsilon subdivisions,2WKBC@28221|Deltaproteobacteria,2MI9G@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Belongs to the acetylglutamate kinase family. ArgB subfamily	argB	GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.2.8	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R02649	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
k141_460_1	1121396.KB893091_gene3502	3.94e-102	335.0	COG0392@1|root,COG2898@1|root,COG0392@2|Bacteria,COG2898@2|Bacteria,1MXH9@1224|Proteobacteria,42N7P@68525|delta/epsilon subdivisions,2WMCJ@28221|Deltaproteobacteria,2MIH1@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Lysylphosphatidylglycerol synthase TM region	-	-	2.3.2.3	ko:K07027,ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	M00726	-	-	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	2.A.1.3.37,4.D.2	-	-	DUF2156,LPG_synthase_TM
k141_1081_1	926559.JoomaDRAFT_3748	4.92e-154	446.0	COG0399@1|root,COG0399@2|Bacteria,4NG9W@976|Bacteroidetes,1HZDU@117743|Flavobacteriia	976|Bacteroidetes	E	Belongs to the DegT DnrJ EryC1 family	-	-	2.6.1.109	ko:K19715	-	-	R11395	RC00160	ko00000,ko01000,ko01005	-	-	-	DegT_DnrJ_EryC1
k141_147_1	177437.HRM2_09850	4.65e-114	335.0	COG0725@1|root,COG0725@2|Bacteria,1MVNA@1224|Proteobacteria,42MZE@68525|delta/epsilon subdivisions,2WKJB@28221|Deltaproteobacteria,2MJDV@213118|Desulfobacterales	28221|Deltaproteobacteria	P	TIGRFAM molybdenum ABC transporter, periplasmic molybdate-binding protein	modA	-	-	ko:K02020	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	iAF987.Gmet_0512	SBP_bac_11
k141_147_2	177437.HRM2_09860	1.66e-131	377.0	COG4149@1|root,COG4149@2|Bacteria,1MUXR@1224|Proteobacteria,42NZV@68525|delta/epsilon subdivisions,2WKDG@28221|Deltaproteobacteria,2MIC6@213118|Desulfobacterales	28221|Deltaproteobacteria	P	TIGRFAM molybdate ABC transporter, inner membrane subunit	modB	-	-	ko:K02018	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	-	BPD_transp_1
k141_147_3	177437.HRM2_09870	3.64e-163	469.0	COG4148@1|root,COG4148@2|Bacteria,1MU8K@1224|Proteobacteria,42NN3@68525|delta/epsilon subdivisions,2WJZP@28221|Deltaproteobacteria,2MJAW@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system	modC	-	3.6.3.29	ko:K02017	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.8	-	-	ABC_tran,TOBE
k141_147_4	525898.Sdel_2061	8.63e-136	412.0	COG4774@1|root,COG4774@2|Bacteria,1QU2Y@1224|Proteobacteria,43CFU@68525|delta/epsilon subdivisions,2YTF6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	PFAM TonB-dependent Receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	TonB_dep_Rec
k141_1787_1	998088.B565_2056	1.43e-60	201.0	COG2206@1|root,COG3437@1|root,COG2206@2|Bacteria,COG3437@2|Bacteria,1R53C@1224|Proteobacteria,1RZQD@1236|Gammaproteobacteria,1Y5KX@135624|Aeromonadales	135624|Aeromonadales	KT	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	HD
k141_4496_6	338966.Ppro_0149	6.11e-16	72.4	COG0526@1|root,COG0526@2|Bacteria	2|Bacteria	CO	cell redox homeostasis	-	-	-	-	-	-	-	-	-	-	-	-	DUF4369,Thioredoxin_3
k141_4833_1	1121396.KB893013_gene3721	9.4e-28	108.0	COG1816@1|root,COG1816@2|Bacteria,1R6Q8@1224|Proteobacteria,42SWZ@68525|delta/epsilon subdivisions,2WPSC@28221|Deltaproteobacteria,2MMF7@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Adenosine/AMP deaminase	-	-	3.5.4.4	ko:K01488	ko00230,ko01100,ko05340,map00230,map01100,map05340	-	R01560,R02556	RC00477	ko00000,ko00001,ko01000	-	-	-	A_deaminase
k141_4123_1	1219065.VPR01S_06_01890	1.9e-78	243.0	COG0583@1|root,COG0583@2|Bacteria,1R7M3@1224|Proteobacteria,1SYRR@1236|Gammaproteobacteria,1XT30@135623|Vibrionales	135623|Vibrionales	K	Bacterial regulatory helix-turn-helix protein, lysR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
k141_4123_2	1348635.BBJY01000007_gene65	8.65e-142	407.0	COG4395@1|root,COG4395@2|Bacteria,1NSUG@1224|Proteobacteria,1RZ3S@1236|Gammaproteobacteria,1XTTA@135623|Vibrionales	135623|Vibrionales	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF1517,Tim44
k141_4123_3	945550.VISI1226_21574	9.28e-102	298.0	COG1309@1|root,COG1309@2|Bacteria,1N0XU@1224|Proteobacteria,1S91U@1236|Gammaproteobacteria,1XVJX@135623|Vibrionales	135623|Vibrionales	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	WHG
k141_4123_4	1219065.VPR01S_03_01700	9.22e-246	696.0	COG0204@1|root,COG0204@2|Bacteria,1MWDY@1224|Proteobacteria,1RRXF@1236|Gammaproteobacteria,1XT85@135623|Vibrionales	135623|Vibrionales	I	COG0477 Permeases of the major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase,MFS_1
k141_4497_1	55601.VANGNB10_cII0329c	2.39e-57	183.0	COG3157@1|root,COG3157@2|Bacteria,1N6DY@1224|Proteobacteria,1SA2B@1236|Gammaproteobacteria,1XYT8@135623|Vibrionales	135623|Vibrionales	S	Type VI secretion system effector, Hcp	-	-	-	ko:K06887	-	-	-	-	ko00000	-	-	-	T6SS_HCP
k141_3804_2	1298593.TOL_0096	8.91e-29	121.0	2ED0T@1|root,336XR@2|Bacteria,1N9CK@1224|Proteobacteria,1SCFD@1236|Gammaproteobacteria,1XMS0@135619|Oceanospirillales	135619|Oceanospirillales	S	LPP20 lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	LPP20
k141_3804_3	717774.Marme_3551	1.37e-73	228.0	COG3417@1|root,COG3417@2|Bacteria,1RA6V@1224|Proteobacteria,1S4SE@1236|Gammaproteobacteria,1XR0D@135619|Oceanospirillales	135619|Oceanospirillales	M	Peptidoglycan-synthase activator LpoB	-	-	-	ko:K07337	-	-	-	-	ko00000	-	-	-	LpoB
k141_3804_4	1208321.D104_07700	1.17e-09	62.4	COG0457@1|root,COG3014@1|root,COG0457@2|Bacteria,COG3014@2|Bacteria,1PD4S@1224|Proteobacteria,1RQ8Y@1236|Gammaproteobacteria,1XJIR@135619|Oceanospirillales	135619|Oceanospirillales	S	protein conserved in bacteria	-	-	-	ko:K09859	-	-	-	-	ko00000	-	-	-	-
k141_1445_2	1232437.KL661965_gene3224	4.05e-176	514.0	COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,42N2U@68525|delta/epsilon subdivisions,2WJRR@28221|Deltaproteobacteria,2MI9B@213118|Desulfobacterales	28221|Deltaproteobacteria	V	ABC transporter transmembrane region	-	-	-	ko:K06147,ko:K18890	ko02010,map02010	M00707	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.106,3.A.1.106.13,3.A.1.106.5,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
k141_5149_1	491952.Mar181_2499	1.18e-214	659.0	2CAAX@1|root,309HW@2|Bacteria,1REWM@1224|Proteobacteria,1S4Y8@1236|Gammaproteobacteria,1XNDT@135619|Oceanospirillales	135619|Oceanospirillales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_5149_3	870967.VIS19158_20002	1.73e-194	568.0	COG3501@1|root,COG3501@2|Bacteria,1MU7Q@1224|Proteobacteria,1RMZS@1236|Gammaproteobacteria,1XUHW@135623|Vibrionales	135623|Vibrionales	M	protein conserved in bacteria	-	GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0006464,GO:0006807,GO:0006996,GO:0007010,GO:0007015,GO:0008144,GO:0008150,GO:0008152,GO:0008154,GO:0009405,GO:0009987,GO:0016043,GO:0016874,GO:0016879,GO:0016881,GO:0017076,GO:0018149,GO:0018153,GO:0018193,GO:0018199,GO:0018205,GO:0018262,GO:0018995,GO:0019538,GO:0022411,GO:0030029,GO:0030036,GO:0030042,GO:0030430,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032984,GO:0033643,GO:0033646,GO:0035639,GO:0036094,GO:0036211,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0043624,GO:0043656,GO:0043657,GO:0043933,GO:0044215,GO:0044216,GO:0044217,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044419,GO:0046872,GO:0051261,GO:0051704,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:0097435,GO:1901265,GO:1901363,GO:1901564	-	ko:K11904	ko03070,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	Phage_GPD
k141_1446_1	96561.Dole_2034	1.58e-73	233.0	COG0002@1|root,COG0002@2|Bacteria,1MVJ6@1224|Proteobacteria,42MDN@68525|delta/epsilon subdivisions,2WINX@28221|Deltaproteobacteria,2MI9X@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde	argC	-	1.2.1.38	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R03443	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
k141_3805_1	1304885.AUEY01000042_gene3595	1.29e-30	131.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42P0K@68525|delta/epsilon subdivisions,2WKDH@28221|Deltaproteobacteria,2MHRI@213118|Desulfobacterales	28221|Deltaproteobacteria	NT	Cache domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,MCPsignal,dCache_1
k141_175_2	452659.RrIowa_0505	1.2e-24	99.0	COG0848@1|root,COG0848@2|Bacteria,1MZ6M@1224|Proteobacteria,2UA46@28211|Alphaproteobacteria,47FDJ@766|Rickettsiales	766|Rickettsiales	U	COG0848 Biopolymer transport protein	tolR	-	-	ko:K03560	-	-	-	-	ko00000,ko02000	1.A.30.2.2	-	-	ExbD
k141_175_3	96561.Dole_2213	2.1e-62	202.0	COG0811@1|root,COG0811@2|Bacteria,1NCWW@1224|Proteobacteria,42PKF@68525|delta/epsilon subdivisions,2WNQ4@28221|Deltaproteobacteria,2MHWF@213118|Desulfobacterales	28221|Deltaproteobacteria	U	PFAM MotA TolQ ExbB proton channel	aglX	-	-	ko:K03562	ko01120,map01120	-	-	-	ko00000,ko02000	1.A.30.2.2	-	-	MotA_ExbB
k141_175_4	1304885.AUEY01000010_gene1643	2.56e-141	409.0	COG2025@1|root,COG2025@2|Bacteria,1MUFI@1224|Proteobacteria,42MH7@68525|delta/epsilon subdivisions,2WK12@28221|Deltaproteobacteria,2MIA2@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM Electron transfer flavoprotein alpha	-	-	-	ko:K03522	-	-	-	-	ko00000,ko04147	-	-	-	ETF,ETF_alpha
k141_175_5	1121396.KB893101_gene477	7.35e-129	372.0	COG2086@1|root,COG2086@2|Bacteria,1MVH6@1224|Proteobacteria,42PYM@68525|delta/epsilon subdivisions,2WJ37@28221|Deltaproteobacteria,2MIP8@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Electron transfer flavoprotein	-	-	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
k141_175_6	1304885.AUEY01000010_gene1641	4.39e-29	115.0	COG0247@1|root,COG0247@2|Bacteria,1MUMH@1224|Proteobacteria,42MIV@68525|delta/epsilon subdivisions,2WJ5X@28221|Deltaproteobacteria,2MIC5@213118|Desulfobacterales	28221|Deltaproteobacteria	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_8,Fer4_9
k141_1447_1	742767.HMPREF9456_02646	1.74e-17	87.4	28IY7@1|root,2Z8VZ@2|Bacteria,4NG80@976|Bacteroidetes,2FNKV@200643|Bacteroidia,22XBM@171551|Porphyromonadaceae	976|Bacteroidetes	S	Domain of unknown function (DUF4857)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4857
k141_4126_1	1121396.KB893035_gene3583	3.1e-164	463.0	COG0437@1|root,COG0437@2|Bacteria,1NBU3@1224|Proteobacteria,42MNU@68525|delta/epsilon subdivisions,2WJRG@28221|Deltaproteobacteria,2MIME@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein	dsrO	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_11,Fer4_4
k141_4126_2	879212.DespoDRAFT_03017	2.02e-63	195.0	arCOG10385@1|root,32SEM@2|Bacteria,1N1IG@1224|Proteobacteria,42TMW@68525|delta/epsilon subdivisions,2WQBW@28221|Deltaproteobacteria,2MK19@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	dsrJ	-	-	-	-	-	-	-	-	-	-	-	-
k141_752_1	1323663.AROI01000010_gene3365	1.09e-29	117.0	COG3177@1|root,COG3177@2|Bacteria,1MV69@1224|Proteobacteria,1RRCR@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	adenylyltransferase that mediates the addition of adenosine 5'-monophosphate (AMP) to specific residues of target proteins	-	GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0006464,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0018117,GO:0018175,GO:0019538,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0036211,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0046872,GO:0046983,GO:0070566,GO:0070733,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564	-	-	-	-	-	-	-	-	-	-	Fic,Fic_N
k141_752_2	1116375.VEJY3_21341	1.78e-209	579.0	COG1082@1|root,COG1082@2|Bacteria,1MUQ0@1224|Proteobacteria,1RRXZ@1236|Gammaproteobacteria,1XUXM@135623|Vibrionales	135623|Vibrionales	G	Xylose isomerase-like TIM barrel	-	-	4.2.1.44	ko:K03335	ko00562,ko01100,ko01120,map00562,map01100,map01120	-	R02782,R05659	RC00782,RC01448	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
k141_752_3	1116375.VEJY3_21331	0.0	900.0	COG4146@1|root,COG4146@2|Bacteria,1MXWV@1224|Proteobacteria,1RR4S@1236|Gammaproteobacteria,1XW1R@135623|Vibrionales	135623|Vibrionales	S	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	yidK	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
k141_752_4	675813.VIB_002219	1.65e-204	569.0	COG0673@1|root,COG0673@2|Bacteria,1MV7C@1224|Proteobacteria,1RSE0@1236|Gammaproteobacteria,1XUDD@135623|Vibrionales	135623|Vibrionales	E	Oxidoreductase family, C-terminal alpha/beta domain	-	-	1.1.1.18,1.1.1.369	ko:K00010	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	-	R01183,R09951	RC00182	ko00000,ko00001,ko01000	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
k141_752_5	1116375.VEJY3_21346	2.38e-187	521.0	COG2207@1|root,COG2207@2|Bacteria,1RAJF@1224|Proteobacteria,1T592@1236|Gammaproteobacteria,1Y3CD@135623|Vibrionales	135623|Vibrionales	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_752_6	1116375.VEJY3_21351	6.67e-68	212.0	COG2207@1|root,COG2207@2|Bacteria	2|Bacteria	K	Transcriptional regulator	-	-	-	ko:K21826	-	-	-	-	ko00000,ko03000	-	-	-	AraC_binding,HTH_18,HTH_AraC
k141_5150_1	195103.CPF_0095	8.65e-172	496.0	COG2376@1|root,COG2376@2|Bacteria,1TP92@1239|Firmicutes,2488D@186801|Clostridia,36E0T@31979|Clostridiaceae	186801|Clostridia	G	Dihydroxyacetone kinase DhaK, subunit	dhaK	-	2.7.1.121,2.7.1.28,2.7.1.29,4.6.1.15	ko:K00863,ko:K05878	ko00051,ko00561,ko00680,ko01100,ko01120,ko01200,ko04622,map00051,map00561,map00680,map01100,map01120,map01200,map04622	M00344	R01011,R01012,R01059	RC00002,RC00015,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Dak1,Dak2
k141_5150_2	1304885.AUEY01000009_gene1954	2.14e-30	132.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42N03@68525|delta/epsilon subdivisions,2WIX4@28221|Deltaproteobacteria,2MINP@213118|Desulfobacterales	28221|Deltaproteobacteria	NT	PFAM chemotaxis sensory transducer	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HBM,MCPsignal,dCache_1
k141_4499_3	1116375.VEJY3_18721	2.37e-284	783.0	COG2710@1|root,COG2710@2|Bacteria,1MWAJ@1224|Proteobacteria,1RQ8X@1236|Gammaproteobacteria,1XZZR@135623|Vibrionales	135623|Vibrionales	C	Nitrogenase component 1 type Oxidoreductase	-	-	-	ko:K02587	-	-	-	-	ko00000	-	-	-	Oxidored_nitro
k141_4499_4	1515746.HR45_08545	1.52e-202	575.0	COG2710@1|root,COG2710@2|Bacteria,1MWSX@1224|Proteobacteria,1RPBI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Belongs to the NifD NifK NifE NifN family	nifN	-	-	ko:K02592	-	-	-	-	ko00000	-	-	-	Oxidored_nitro
k141_3569_1	1116375.VEJY3_23066	1.27e-17	81.6	COG3437@1|root,COG3437@2|Bacteria,1MUB8@1224|Proteobacteria,1RPH3@1236|Gammaproteobacteria,1XT5R@135623|Vibrionales	135623|Vibrionales	T	COG3437 Response regulator containing a CheY-like receiver domain and an HD-GYP domain	-	-	-	ko:K07814	-	-	-	-	ko00000,ko02022	-	-	-	HD,HD_5,Response_reg
k141_3569_2	1116375.VEJY3_23071	1.18e-147	442.0	COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,1RRSJ@1236|Gammaproteobacteria,1Y0HR@135623|Vibrionales	135623|Vibrionales	T	Cache domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,dCache_1
k141_1512_1	225849.swp_5011	4.41e-17	87.8	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,2QAQI@267890|Shewanellaceae	1236|Gammaproteobacteria	NT	PFAM histidine kinase, HAMP region domain protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal,dCache_1
k141_4226_1	525897.Dbac_1148	1.59e-22	105.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42NNT@68525|delta/epsilon subdivisions,2WJDP@28221|Deltaproteobacteria,2M8A1@213115|Desulfovibrionales	28221|Deltaproteobacteria	NT	histidine kinase HAMP region domain protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	DUF3365,HAMP,MCPsignal,dCache_1
k141_258_1	933262.AXAM01000015_gene116	1.21e-117	357.0	COG0728@1|root,COG0728@2|Bacteria,1MUH0@1224|Proteobacteria,42M28@68525|delta/epsilon subdivisions,2WJPF@28221|Deltaproteobacteria,2MIBD@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane	murJ	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
k141_4227_1	1341157.RF007C_00100	5.61e-81	261.0	COG2274@1|root,COG2274@2|Bacteria,1V77J@1239|Firmicutes,25E7C@186801|Clostridia,3WSU8@541000|Ruminococcaceae	186801|Clostridia	V	Peptidase C39 family	-	-	-	ko:K11004	ko02010,ko03070,ko05133,map02010,map03070,map05133	M00325,M00575	-	-	ko00000,ko00001,ko00002,ko02000,ko02044	3.A.1.109.1,3.A.1.109.2	-	-	ABC_membrane,ABC_tran,Peptidase_C39
k141_1513_1	675813.VIB_001184	4.81e-96	292.0	COG3493@1|root,COG3493@2|Bacteria,1NKCA@1224|Proteobacteria,1RN6E@1236|Gammaproteobacteria,1XUGC@135623|Vibrionales	135623|Vibrionales	C	2-hydroxycarboxylate transporter family	-	-	-	-	-	-	-	-	-	-	-	-	2HCT
k141_2486_1	1396141.BATP01000024_gene835	1.29e-08	57.0	COG5351@1|root,COG5351@2|Bacteria	2|Bacteria	S	Uncharacterized protein conserved in bacteria (DUF2169)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2169
k141_2486_2	483219.LILAB_07435	6.58e-08	62.4	COG0304@1|root,COG0304@2|Bacteria,1PXMJ@1224|Proteobacteria,434PA@68525|delta/epsilon subdivisions,2WZ0J@28221|Deltaproteobacteria,2Z12H@29|Myxococcales	28221|Deltaproteobacteria	IQ	beta-ketoacyl-acyl-carrier-protein synthase II activity	-	-	2.3.1.41	ko:K00647	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	-
k141_2486_3	215803.DB30_4823	5.42e-75	254.0	COG1475@1|root,COG1475@2|Bacteria,1RIT4@1224|Proteobacteria,4382V@68525|delta/epsilon subdivisions,2X3CV@28221|Deltaproteobacteria,2YVGI@29|Myxococcales	28221|Deltaproteobacteria	K	Domain of unknown function (DUF4150)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4150
k141_2486_4	529507.PMI0756	1.85e-22	103.0	2DMJQ@1|root,32S16@2|Bacteria,1N4SH@1224|Proteobacteria,1SZVV@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_2486_6	529507.PMI0756	7.68e-25	108.0	2DMJQ@1|root,32S16@2|Bacteria,1N4SH@1224|Proteobacteria,1SZVV@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_2486_8	29495.EA26_00065	3.31e-134	387.0	COG1518@1|root,COG1518@2|Bacteria,1MUXH@1224|Proteobacteria,1RP48@1236|Gammaproteobacteria,1XTGH@135623|Vibrionales	135623|Vibrionales	L	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette	cas1	-	-	ko:K15342	-	-	-	-	ko00000,ko02048,ko03400	-	-	-	Cas_Cas1
k141_279_1	879212.DespoDRAFT_02106	0.0	1617.0	COG1073@1|root,COG1073@2|Bacteria,1RFNW@1224|Proteobacteria,431KH@68525|delta/epsilon subdivisions,2WWRB@28221|Deltaproteobacteria,2MNVE@213118|Desulfobacterales	28221|Deltaproteobacteria	S	alpha beta	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_1916_1	1392488.JHZY01000004_gene2542	2.75e-34	124.0	COG4675@1|root,COG4675@2|Bacteria,4NQJR@976|Bacteroidetes,1I31T@117743|Flavobacteriia	976|Bacteroidetes	S	PFAM phage Tail Collar domain	-	-	-	-	-	-	-	-	-	-	-	-	Collar
k141_1916_2	717606.PaecuDRAFT_2133	1.05e-34	126.0	COG4675@1|root,COG4675@2|Bacteria,1V943@1239|Firmicutes,4HJCC@91061|Bacilli,26YNV@186822|Paenibacillaceae	91061|Bacilli	S	Phage Tail Collar Domain	-	-	-	-	-	-	-	-	-	-	-	-	Collar
k141_4237_2	1328313.DS2_19321	1.08e-151	432.0	COG3039@1|root,COG3039@2|Bacteria,1Q9AW@1224|Proteobacteria,1RNU1@1236|Gammaproteobacteria,46A7P@72275|Alteromonadaceae	1236|Gammaproteobacteria	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_3
k141_4237_3	688245.CtCNB1_4154	2.59e-54	186.0	COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,2VIAP@28216|Betaproteobacteria,4A9QF@80864|Comamonadaceae	28216|Betaproteobacteria	V	SMART AAA ATPase	-	-	-	ko:K06147,ko:K18893	ko02010,map02010	-	-	-	ko00000,ko00001,ko02000	3.A.1,3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
k141_1533_1	1214065.BAGV01000032_gene716	1.67e-60	220.0	COG3127@1|root,COG3127@2|Bacteria,1MU9R@1224|Proteobacteria,1RM8Y@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	ABC-type transport system involved in lysophospholipase L1 biosynthesis permease component	ybbP	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX
k141_2505_1	579405.Dd703_0482	2.97e-51	188.0	COG0689@1|root,COG2931@1|root,COG3210@1|root,COG4625@1|root,COG0689@2|Bacteria,COG2931@2|Bacteria,COG3210@2|Bacteria,COG4625@2|Bacteria,1MU7T@1224|Proteobacteria,1RNK8@1236|Gammaproteobacteria,2JC9A@204037|Dickeya	1236|Gammaproteobacteria	QU	Domain of unknown function (DUF4347)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4347,He_PIG
k141_5198_2	1121396.KB893082_gene927	3.89e-197	555.0	COG0665@1|root,COG0665@2|Bacteria,1MVIZ@1224|Proteobacteria,42REB@68525|delta/epsilon subdivisions,2WNWD@28221|Deltaproteobacteria,2MKRA@213118|Desulfobacterales	28221|Deltaproteobacteria	E	FAD dependent oxidoreductase	thiO	-	1.4.3.19	ko:K03153	ko00730,ko01100,map00730,map01100	-	R07463	RC01788	ko00000,ko00001,ko01000	-	-	-	DAO
k141_5198_3	1121396.KB893082_gene928	8.4e-234	655.0	COG0446@1|root,COG0446@2|Bacteria,1MXA9@1224|Proteobacteria,42TSQ@68525|delta/epsilon subdivisions,2WQZT@28221|Deltaproteobacteria,2MK7P@213118|Desulfobacterales	28221|Deltaproteobacteria	C	BFD-like [2Fe-2S] binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer2_BFD,Pyr_redox_2
k141_5198_4	563192.HMPREF0179_01880	1.02e-20	87.0	COG0479@1|root,COG0479@2|Bacteria,1QY57@1224|Proteobacteria,43CZK@68525|delta/epsilon subdivisions,2X87U@28221|Deltaproteobacteria,2MFX3@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	2Fe-2S iron-sulfur cluster binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer2_4
k141_5198_5	768706.Desor_2681	1.65e-55	176.0	COG0251@1|root,COG0251@2|Bacteria,1V5WP@1239|Firmicutes,24HEV@186801|Clostridia,265FT@186807|Peptococcaceae	186801|Clostridia	J	Endoribonuclease L-PSP	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
k141_5198_6	1348635.BBJY01000006_gene453	2.23e-246	687.0	COG0531@1|root,COG0531@2|Bacteria,1R4PP@1224|Proteobacteria,1RP8U@1236|Gammaproteobacteria,1Y00J@135623|Vibrionales	135623|Vibrionales	E	Amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
k141_5198_7	1116375.VEJY3_23961	3.88e-244	674.0	COG2423@1|root,COG2423@2|Bacteria,1PPG3@1224|Proteobacteria,1RYPX@1236|Gammaproteobacteria,1XVP6@135623|Vibrionales	135623|Vibrionales	E	Ornithine cyclodeaminase/mu-crystallin family	-	-	-	-	-	-	-	-	-	-	-	-	OCD_Mu_crystall
k141_5198_8	1348635.BBJY01000006_gene449	3.8e-127	369.0	COG2207@1|root,COG2207@2|Bacteria,1R4RI@1224|Proteobacteria,1RZFI@1236|Gammaproteobacteria,1XX1W@135623|Vibrionales	135623|Vibrionales	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
k141_5198_9	672.VV93_v1c30800	2.01e-111	335.0	COG1162@1|root,COG1162@2|Bacteria,1MUEF@1224|Proteobacteria,1RMMB@1236|Gammaproteobacteria,1XSIW@135623|Vibrionales	135623|Vibrionales	S	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit	rsgA2	-	3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100	-	R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009	-	-	-	RsgA_GTPase
k141_5198_10	1219077.VAZ01S_073_00210	4.14e-109	318.0	COG1186@1|root,COG1186@2|Bacteria,1R9YA@1224|Proteobacteria,1RR3F@1236|Gammaproteobacteria	1236|Gammaproteobacteria	J	chain release factor	prfH	-	-	ko:K02839	-	-	-	-	ko00000,ko03012	-	-	-	RF-1
k141_5198_11	392500.Swoo_3903	5.64e-234	649.0	COG1690@1|root,COG1690@2|Bacteria,1MUHA@1224|Proteobacteria,1RN50@1236|Gammaproteobacteria,2QDS8@267890|Shewanellaceae	1236|Gammaproteobacteria	S	tRNA-splicing ligase RtcB	rtcB	-	6.5.1.3	ko:K14415,ko:K18148	ko01501,map01501	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	RtcB
k141_5198_12	1187848.AJYQ01000005_gene325	2.26e-22	99.8	COG0834@1|root,COG0834@2|Bacteria,1N20Q@1224|Proteobacteria,1T9FW@1236|Gammaproteobacteria,1XYRI@135623|Vibrionales	135623|Vibrionales	ET	Bacterial extracellular solute-binding proteins, family 3	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
k141_5198_13	1348635.BBJY01000010_gene1373	3.66e-186	519.0	COG2207@1|root,COG2207@2|Bacteria,1QKC9@1224|Proteobacteria,1RMG3@1236|Gammaproteobacteria,1XTWR@135623|Vibrionales	135623|Vibrionales	K	COG2207 AraC-type DNA-binding domain-containing proteins	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18,HTH_AraC
k141_5198_14	1348635.BBJY01000010_gene1372	4.87e-122	352.0	COG1296@1|root,COG1296@2|Bacteria,1MVGN@1224|Proteobacteria,1S2AK@1236|Gammaproteobacteria,1XSZ2@135623|Vibrionales	135623|Vibrionales	E	branched-chain amino acid permease (azaleucine resistance)	-	-	-	-	-	-	-	-	-	-	-	-	AzlC
k141_5198_15	1348635.BBJY01000010_gene1371	2e-53	169.0	COG4392@1|root,COG4392@2|Bacteria,1N6Z1@1224|Proteobacteria,1SCAB@1236|Gammaproteobacteria,1XYAS@135623|Vibrionales	135623|Vibrionales	S	branched-chain amino acid	-	-	-	-	-	-	-	-	-	-	-	-	AzlD
k141_5198_16	55601.VANGNB10_cI2313	0.0	991.0	COG0737@1|root,COG0737@2|Bacteria,1MU11@1224|Proteobacteria,1RMQV@1236|Gammaproteobacteria,1XSV2@135623|Vibrionales	135623|Vibrionales	F	Belongs to the 5'-nucleotidase family	cpdB	-	3.1.3.6,3.1.4.16	ko:K01119	ko00230,ko00240,map00230,map00240	-	R01562,R01877,R02148,R02370,R03537,R03538,R03929,R05135	RC00078,RC00296	ko00000,ko00001,ko01000	-	-	-	5_nucleotid_C,Metallophos
k141_5198_17	90371.CY43_22465	0.0	1079.0	COG0243@1|root,COG0243@2|Bacteria,1NR6J@1224|Proteobacteria,1RMVE@1236|Gammaproteobacteria,3ZKUF@590|Salmonella	1236|Gammaproteobacteria	C	Molybdopterin oxidoreductase Fe4S4 domain	-	-	1.7.2.3,1.8.5.3,1.97.1.9	ko:K07306,ko:K07309,ko:K07310,ko:K07811,ko:K08351	ko00450,ko00780,ko00920,ko01100,ko02020,map00450,map00780,map00920,map01100,map02020	-	R07229,R09501,R10127	RC02420,RC02555,RC03056	ko00000,ko00001,ko01000,ko02000	5.A.3.3,5.A.3.4	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding,TAT_signal
k141_5198_18	1141662.OOA_05971	7.05e-123	353.0	COG0437@1|root,COG0437@2|Bacteria,1MU5T@1224|Proteobacteria,1RPIC@1236|Gammaproteobacteria,3Z7DF@586|Providencia	1236|Gammaproteobacteria	C	anaerobic dimethyl sulfoxide reductase, subunit B	dmsB	-	-	ko:K07307	ko00920,map00920	-	R09501	RC02555	ko00000,ko00001,ko02000	5.A.3.3	-	-	Fer4_11,Fer4_3,Fer4_4
k141_5198_19	35703.DQ02_24445	7.71e-39	143.0	COG3302@1|root,COG3302@2|Bacteria,1PA8U@1224|Proteobacteria,1RRGH@1236|Gammaproteobacteria,3WXGR@544|Citrobacter	1236|Gammaproteobacteria	S	DMSO reductase anchor subunit (DmsC)	-	-	-	ko:K07308	ko00920,map00920	-	R09501	RC02555	ko00000,ko00001,ko02000	5.A.3.3	-	-	DmsC
k141_5198_20	1111728.ATYS01000009_gene531	2.22e-50	168.0	COG3381@1|root,COG3381@2|Bacteria,1RF2Y@1224|Proteobacteria,1S3Q9@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Required for biogenesis assembly of DMSO reductase, but not for the interaction of the DmsA signal peptide with the Tat system. May be part of a chaperone cascade complex that facilitates a folding-maturation pathway for the substrate protein	-	-	-	-	-	-	-	-	-	-	-	-	Nitrate_red_del
k141_5198_22	357804.Ping_2427	1.44e-174	494.0	COG0385@1|root,COG0385@2|Bacteria,1MUMM@1224|Proteobacteria,1RN2S@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Bile acid sodium symporter	-	-	-	ko:K14347	-	-	-	-	ko00000,ko02000,ko04147	2.A.93.1	-	-	SBF_like
k141_5198_23	1448139.AI20_07185	3.54e-17	76.6	2EG60@1|root,339XW@2|Bacteria,1NM77@1224|Proteobacteria,1SGGT@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_5198_24	223926.28806438	0.0	1415.0	COG0243@1|root,COG0243@2|Bacteria,1NSXR@1224|Proteobacteria,1T2GI@1236|Gammaproteobacteria,1Y2I6@135623|Vibrionales	135623|Vibrionales	C	Molybdopterin oxidoreductase Fe4S4 domain	-	-	1.8.5.3	ko:K07306	ko00920,map00920	-	R09501	RC02555	ko00000,ko00001,ko01000,ko02000	5.A.3.3	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
k141_5198_25	1454202.PPBDW_90434___1	1.05e-136	388.0	COG0437@1|root,COG0437@2|Bacteria,1MU5T@1224|Proteobacteria,1RPIC@1236|Gammaproteobacteria,1XVJH@135623|Vibrionales	135623|Vibrionales	C	4Fe-4S dicluster domain	dmsB	-	-	ko:K07307	ko00920,map00920	-	R09501	RC02555	ko00000,ko00001,ko02000	5.A.3.3	-	-	Fer4_11,Fer4_4
k141_5198_26	1280001.BAOA01000073_gene3336	1.38e-108	323.0	COG3302@1|root,COG3302@2|Bacteria,1PA8U@1224|Proteobacteria,1RRGH@1236|Gammaproteobacteria,1XVX1@135623|Vibrionales	135623|Vibrionales	S	DMSO reductase anchor subunit (DmsC)	-	-	-	ko:K07308	ko00920,map00920	-	R09501	RC02555	ko00000,ko00001,ko02000	5.A.3.3	-	-	DmsC
k141_5198_27	220341.16505295	9.31e-26	106.0	COG3381@1|root,COG3381@2|Bacteria,1RF2Y@1224|Proteobacteria,1S3Q9@1236|Gammaproteobacteria,3ZK3S@590|Salmonella	1236|Gammaproteobacteria	S	Nitrate reductase delta subunit	-	-	-	-	-	-	-	-	-	-	-	-	Nitrate_red_del
k141_5198_30	393595.ABO_2041	3.78e-41	144.0	COG0791@1|root,COG0791@2|Bacteria,1N0EE@1224|Proteobacteria,1RR2X@1236|Gammaproteobacteria,1XKHX@135619|Oceanospirillales	135619|Oceanospirillales	M	COG0791 Cell wall-associated hydrolases (invasion-associated proteins)	-	-	3.4.17.13	ko:K13694,ko:K13695	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	NLPC_P60
k141_5198_32	500637.PROVRUST_05092	1.93e-38	138.0	COG0558@1|root,COG0558@2|Bacteria,1RE0I@1224|Proteobacteria,1S2UQ@1236|Gammaproteobacteria,3Z8QD@586|Providencia	1236|Gammaproteobacteria	I	Psort location CytoplasmicMembrane, score	ynbA	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	2.7.8.5	ko:K00995	ko00564,ko01100,map00564,map01100	-	R01801	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
k141_5198_33	494416.AYXN01000041_gene588	8.99e-182	543.0	COG0558@1|root,COG2267@1|root,COG0558@2|Bacteria,COG2267@2|Bacteria,1MWF5@1224|Proteobacteria,1RNQR@1236|Gammaproteobacteria,3NKXM@468|Moraxellaceae	1236|Gammaproteobacteria	I	Putative methyltransferase	ynbC	GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0008150,GO:0008152,GO:0016020,GO:0016298,GO:0016787,GO:0016788,GO:0044238,GO:0071704	-	-	-	-	-	-	-	-	-	-	Hydrolase_4,Methyltransf_20
k141_5198_34	1219076.N646_4093	5.35e-174	493.0	COG1609@1|root,COG1609@2|Bacteria,1MVUR@1224|Proteobacteria,1RN2K@1236|Gammaproteobacteria,1XTVU@135623|Vibrionales	135623|Vibrionales	K	Ribose operon repressor	rbsR	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
k141_5198_35	29495.EA26_12030	1.91e-146	421.0	COG0524@1|root,COG0524@2|Bacteria,1MV5B@1224|Proteobacteria,1RNVY@1236|Gammaproteobacteria,1XUEM@135623|Vibrionales	135623|Vibrionales	H	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway	rbsK	-	2.7.1.15	ko:K00852	ko00030,map00030	-	R01051,R02750	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
k141_5198_36	1205908.AKXW01000176_gene3064	8.5e-164	463.0	COG1879@1|root,COG1879@2|Bacteria,1NRXG@1224|Proteobacteria,1RPBV@1236|Gammaproteobacteria,1XUF5@135623|Vibrionales	135623|Vibrionales	G	ABC-type sugar transport system, periplasmic component	rbsB	-	-	ko:K10439	ko02010,ko02030,map02010,map02030	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	Peripla_BP_4
k141_5198_38	1190606.AJYG01000016_gene3401	3.17e-280	775.0	COG1129@1|root,COG1129@2|Bacteria,1MU22@1224|Proteobacteria,1RMCH@1236|Gammaproteobacteria,1XTBT@135623|Vibrionales	135623|Vibrionales	P	Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system	rbsA	GO:0003674,GO:0003824,GO:0005215,GO:0006810,GO:0008150,GO:0008643,GO:0015144,GO:0015145,GO:0015146,GO:0015399,GO:0015405,GO:0015407,GO:0015591,GO:0015608,GO:0015611,GO:0015749,GO:0015750,GO:0015752,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0034219,GO:0042623,GO:0042626,GO:0043211,GO:0043492,GO:0051119,GO:0051179,GO:0051234,GO:0055085,GO:0071702	3.6.3.17	ko:K10441	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	ABC_tran
k141_5198_39	1248232.BANQ01000130_gene902	9.11e-62	194.0	COG1869@1|root,COG1869@2|Bacteria,1RI53@1224|Proteobacteria,1S60T@1236|Gammaproteobacteria,1XX9V@135623|Vibrionales	135623|Vibrionales	G	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose	rbsD	GO:0003674,GO:0003824,GO:0005215,GO:0006810,GO:0008150,GO:0008643,GO:0015144,GO:0015145,GO:0015146,GO:0015399,GO:0015405,GO:0015407,GO:0015591,GO:0015608,GO:0015611,GO:0015749,GO:0015750,GO:0015752,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0034219,GO:0042623,GO:0042626,GO:0043211,GO:0043492,GO:0051119,GO:0051179,GO:0051234,GO:0055085,GO:0071702	5.4.99.62	ko:K06726	ko02010,map02010	-	R08247	RC02247	ko00000,ko00001,ko01000	-	-	-	RbsD_FucU
k141_5198_40	796620.VIBC2010_04524	1.35e-12	67.0	COG3783@1|root,COG3783@2|Bacteria,1N8JG@1224|Proteobacteria,1SD88@1236|Gammaproteobacteria,1XXVF@135623|Vibrionales	135623|Vibrionales	C	COG3783 Soluble cytochrome b562	-	-	-	ko:K15536	-	-	-	-	ko00000	-	-	-	Cytochrom_B562
k141_5198_42	1191523.MROS_2388	4.65e-219	631.0	COG3250@1|root,COG3250@2|Bacteria	2|Bacteria	G	beta-galactosidase activity	-	-	3.1.1.53	ko:K05970	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_hydro_2_N,SASA
k141_5198_43	1245469.S58_29670	1.84e-152	451.0	COG2355@1|root,COG3568@1|root,COG2355@2|Bacteria,COG3568@2|Bacteria,1R8HG@1224|Proteobacteria,2UNI6@28211|Alphaproteobacteria,3K34W@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	Ricin-type beta-trefoil	-	-	-	-	-	-	-	-	-	-	-	-	Jacalin,Ricin_B_lectin
k141_566_1	1121405.dsmv_0617	1.73e-12	66.6	COG1148@1|root,COG1148@2|Bacteria,1Q0ZF@1224|Proteobacteria,42NHH@68525|delta/epsilon subdivisions,2WJ6M@28221|Deltaproteobacteria,2MIS1@213118|Desulfobacterales	28221|Deltaproteobacteria	C	FAD dependent oxidoreductase	qmoA	-	-	ko:K16885	-	-	-	-	ko00000	-	-	-	FAD_oxidored,NAD_binding_8,Pyr_redox_2
k141_566_2	1304885.AUEY01000017_gene3749	0.0	1241.0	COG1053@1|root,COG1053@2|Bacteria,1NZBR@1224|Proteobacteria,42PSJ@68525|delta/epsilon subdivisions,2WJDD@28221|Deltaproteobacteria,2MHWQ@213118|Desulfobacterales	28221|Deltaproteobacteria	C	reductase, alpha subunit	aprA	-	1.8.99.2	ko:K00394	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00596	R00860,R04927,R08553	RC00007,RC01239,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2
k141_566_3	1304885.AUEY01000017_gene3750	1.8e-28	106.0	COG1146@1|root,COG1146@2|Bacteria,1RC9N@1224|Proteobacteria,42QXF@68525|delta/epsilon subdivisions,2WMRJ@28221|Deltaproteobacteria,2MJFT@213118|Desulfobacterales	28221|Deltaproteobacteria	C	reductase, beta subunit	aprB	-	1.8.99.2	ko:K00395	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00596	R00860,R04927,R08553	RC00007,RC01239,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	-	APS-reductase_C,Fer4,Fer4_9
k141_794_1	1167006.UWK_00267	4.36e-30	132.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,439X1@68525|delta/epsilon subdivisions,2WJBG@28221|Deltaproteobacteria,2MI1C@213118|Desulfobacterales	28221|Deltaproteobacteria	NT	Protein of unknown function (DUF3365)	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	DUF3365,HAMP,MCPsignal
k141_2229_1	316067.Geob_2777	6.65e-28	111.0	COG0150@1|root,COG0150@2|Bacteria,1MURG@1224|Proteobacteria,42KZT@68525|delta/epsilon subdivisions,2WIXY@28221|Deltaproteobacteria,43RZ8@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	AIR synthase related protein domain protein	purM	-	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1844	AIRS,AIRS_C
k141_2229_2	1304885.AUEY01000028_gene2791	8.97e-132	385.0	COG0533@1|root,COG0533@2|Bacteria,1MU6S@1224|Proteobacteria,42MHX@68525|delta/epsilon subdivisions,2WIKS@28221|Deltaproteobacteria,2MI6H@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
k141_2229_3	264462.Bd3895	1.77e-41	159.0	COG1472@1|root,COG1472@2|Bacteria,1MVAJ@1224|Proteobacteria,42N8K@68525|delta/epsilon subdivisions,2MSTA@213481|Bdellovibrionales,2WN0Z@28221|Deltaproteobacteria	213481|Bdellovibrionales	G	PFAM glycoside hydrolase, family 3 domain protein	-	-	3.2.1.52	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	M00628	R00022,R05963,R07809,R07810,R10831	RC00049	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyco_hydro_3,Glyco_hydro_3_C
k141_2229_5	933262.AXAM01000030_gene807	3.69e-97	293.0	COG1559@1|root,COG1559@2|Bacteria,1MUQF@1224|Proteobacteria,42MPA@68525|delta/epsilon subdivisions,2WJ0Q@28221|Deltaproteobacteria,2MI3R@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation	mltG	-	-	ko:K07082	-	-	-	-	ko00000	-	-	-	YceG
k141_3602_1	999141.GME_18835	1.9e-12	75.1	COG1533@1|root,COG1533@2|Bacteria,1MW0H@1224|Proteobacteria,1RQNF@1236|Gammaproteobacteria,1XHG6@135619|Oceanospirillales	135619|Oceanospirillales	L	Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
k141_4238_1	177439.DP0005	2.36e-107	317.0	COG0106@1|root,COG0106@2|Bacteria,1R6J2@1224|Proteobacteria,43B0N@68525|delta/epsilon subdivisions,2X6EQ@28221|Deltaproteobacteria,2MICV@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Belongs to the HisA HisF family	-	-	5.3.1.16	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04640	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
k141_280_1	933262.AXAM01000030_gene797	1.65e-26	105.0	COG0289@1|root,COG0289@2|Bacteria,1QB39@1224|Proteobacteria,42NRC@68525|delta/epsilon subdivisions,2WJGM@28221|Deltaproteobacteria,2MJ2I@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Belongs to the DapB family	-	-	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	-	DapB_C,DapB_N
k141_280_2	5722.XP_001300753.1	0.000292	50.8	COG0666@1|root,KOG0504@2759|Eukaryota	5722.XP_001300753.1|-	I	protein ubiquitination	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_3931_1	1454202.PPBDW_60046___1	1.68e-155	451.0	COG0582@1|root,COG0582@2|Bacteria,1MU23@1224|Proteobacteria,1RNE0@1236|Gammaproteobacteria,1XWF2@135623|Vibrionales	135623|Vibrionales	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Arm-DNA-bind_3,Phage_integrase
k141_3931_2	1219080.VEZ01S_08_00700	7.12e-118	345.0	2B9YA@1|root,323BS@2|Bacteria,1RHWM@1224|Proteobacteria,1S6UP@1236|Gammaproteobacteria,1XVZZ@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_3931_3	1328313.DS2_18618	4.02e-30	108.0	COG4118@1|root,COG4118@2|Bacteria,1NH4W@1224|Proteobacteria,1SGFN@1236|Gammaproteobacteria,468ZW@72275|Alteromonadaceae	1236|Gammaproteobacteria	D	Antitoxin component of a toxin-antitoxin (TA) module	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
k141_3931_4	1328313.DS2_18623	2.04e-70	214.0	COG3744@1|root,COG3744@2|Bacteria,1N0J5@1224|Proteobacteria,1S6CA@1236|Gammaproteobacteria,467PT@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
k141_3931_5	298386.PBPRA2541	0.0	1479.0	COG1196@1|root,COG1196@2|Bacteria,1R63K@1224|Proteobacteria,1S11B@1236|Gammaproteobacteria,1XWEF@135623|Vibrionales	135623|Vibrionales	D	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_3931_6	298386.PBPRA2540	2.41e-270	748.0	28NC7@1|root,2ZBF9@2|Bacteria,1Q40Q@1224|Proteobacteria,1S1GF@1236|Gammaproteobacteria,1XVKW@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_3931_7	1219080.VEZ01S_08_00730	1.76e-111	322.0	2BV8H@1|root,32QN7@2|Bacteria,1MYPH@1224|Proteobacteria,1S8Q8@1236|Gammaproteobacteria,1XVS4@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_3931_8	345073.VC395_0320	1.02e-170	484.0	COG3177@1|root,COG3177@2|Bacteria,1MWAU@1224|Proteobacteria,1RRHZ@1236|Gammaproteobacteria,1XX5K@135623|Vibrionales	135623|Vibrionales	K	Fic/DOC family	-	-	-	-	-	-	-	-	-	-	-	-	Fic
k141_3931_9	1238450.VIBNISOn1_1530051	1.24e-59	196.0	COG2931@1|root,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	3.1.3.1,3.1.3.8,3.1.4.46	ko:K01077,ko:K01083,ko:K01113,ko:K01126	ko00562,ko00564,ko00730,ko00790,ko01100,ko02020,map00562,map00564,map00730,map00790,map01100,map02020	M00126	R01030,R01470,R02135,R03371,R04620	RC00017,RC00078,RC00425	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	-	-	-	5_nucleotid_C,Alk_phosphatase,DUF4114,Exo_endo_phos,GDPD,HemolysinCabind,PhoD,PhoD_N,Phytase,Phytase-like
k141_3931_10	243277.VC_0277	3.57e-69	211.0	COG0789@1|root,COG0789@2|Bacteria,1MZ3P@1224|Proteobacteria,1SA5G@1236|Gammaproteobacteria,1Y2TN@135623|Vibrionales	135623|Vibrionales	K	MerR, DNA binding	zntR	-	-	ko:K13638	-	-	-	-	ko00000,ko03000	-	-	-	MerR,MerR-DNA-bind,MerR_1
k141_2508_1	426117.M446_0172	5.18e-38	157.0	COG3321@1|root,COG3321@2|Bacteria,1R89Z@1224|Proteobacteria,2UR2U@28211|Alphaproteobacteria,1JS6P@119045|Methylobacteriaceae	28211|Alphaproteobacteria	CQ	PFAM short-chain dehydrogenase reductase SDR	-	-	-	ko:K12436	-	-	-	-	ko00000,ko01004	-	-	-	ADH_zinc_N_2,Acyl_transf_1,KAsynt_C_assoc,KR,Ketoacyl-synt_C,PP-binding,PS-DH,ketoacyl-synt
k141_281_1	439235.Dalk_0405	4.41e-123	367.0	COG1220@1|root,COG1220@2|Bacteria,1MVK9@1224|Proteobacteria,42M48@68525|delta/epsilon subdivisions,2WISV@28221|Deltaproteobacteria,2MIBH@213118|Desulfobacterales	28221|Deltaproteobacteria	O	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis	hslU	-	-	ko:K03667	-	-	-	-	ko00000,ko03110	-	-	-	AAA_2,ClpB_D2-small
k141_281_2	439235.Dalk_0404	5.16e-56	180.0	COG5405@1|root,COG5405@2|Bacteria,1MVF2@1224|Proteobacteria,42MEH@68525|delta/epsilon subdivisions,2WMSC@28221|Deltaproteobacteria,2MJC6@213118|Desulfobacterales	28221|Deltaproteobacteria	O	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery	hslV	-	3.4.25.2	ko:K01419	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Proteasome
k141_5200_1	1051646.VITU9109_00580	2.41e-69	228.0	COG0582@1|root,COG0582@2|Bacteria,1MVZB@1224|Proteobacteria,1RSCD@1236|Gammaproteobacteria,1XW86@135623|Vibrionales	135623|Vibrionales	L	Phage integrase family	-	-	-	ko:K14059	-	-	-	-	ko00000	-	-	-	Phage_integrase
k141_1918_1	469595.CSAG_04485	3.85e-149	426.0	COG2169@1|root,COG2169@2|Bacteria,1R4BQ@1224|Proteobacteria,1RTAM@1236|Gammaproteobacteria,3WXSM@544|Citrobacter	1236|Gammaproteobacteria	F	helix_turn_helix, arabinose operon control protein	melR	GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:2000112,GO:2001141	-	-	-	-	-	-	-	-	-	-	HTH_18,HTH_AraC
k141_1918_2	1195246.AGRI_02635	1.95e-40	135.0	COG4453@1|root,COG4453@2|Bacteria	2|Bacteria	K	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF1778
k141_5389_26	484770.UFO1_1179	3.38e-47	157.0	COG3708@1|root,COG3708@2|Bacteria,1TPI9@1239|Firmicutes	1239|Firmicutes	K	Transcriptional regulator	ydeE7	-	-	ko:K13653	-	-	-	-	ko00000,ko03000	-	-	-	Cass2,GyrI-like,HTH_18
k141_3747_2	674977.VMC_16190	6.54e-29	108.0	COG0235@1|root,COG0235@2|Bacteria,1MW7B@1224|Proteobacteria,1RS8X@1236|Gammaproteobacteria,1XVYB@135623|Vibrionales	135623|Vibrionales	G	Class II Aldolase and Adducin N-terminal domain	-	-	4.1.1.104	ko:K22130	-	-	-	-	ko00000,ko01000	-	-	-	Aldolase_II
k141_2724_1	1304885.AUEY01000019_gene1174	4.31e-60	198.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,1MUJM@1224|Proteobacteria,42M2M@68525|delta/epsilon subdivisions,2WJ5H@28221|Deltaproteobacteria,2MHSU@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	guaB	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH,NMO
k141_2724_2	1304885.AUEY01000019_gene1173	0.0	1382.0	COG0587@1|root,COG0587@2|Bacteria,1MUIF@1224|Proteobacteria,42MGP@68525|delta/epsilon subdivisions,2WIZ2@28221|Deltaproteobacteria,2MI79@213118|Desulfobacterales	28221|Deltaproteobacteria	L	DNA polymerase III alpha subunit	dnaE	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
k141_4767_1	1408473.JHXO01000012_gene440	3.2e-32	119.0	COG2431@1|root,COG2431@2|Bacteria,4NMM0@976|Bacteroidetes,2FNT2@200643|Bacteroidia	976|Bacteroidetes	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	Lys_export
k141_4767_2	1349822.NSB1T_13195	7.2e-13	65.9	2EFF3@1|root,3397Y@2|Bacteria,4NVP1@976|Bacteroidetes,2FTU1@200643|Bacteroidia,22YZ8@171551|Porphyromonadaceae	976|Bacteroidetes	S	Lysine exporter LysO	-	-	-	-	-	-	-	-	-	-	-	-	Lys_export
k141_5107_2	223926.28805439	1.05e-198	565.0	COG0770@1|root,COG0770@2|Bacteria,1QTSF@1224|Proteobacteria,1RMGD@1236|Gammaproteobacteria,1XUMH@135623|Vibrionales	135623|Vibrionales	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
k141_5107_3	1517681.HW45_00870	8.97e-207	589.0	COG0769@1|root,COG0769@2|Bacteria,1MU6P@1224|Proteobacteria,1RMD6@1236|Gammaproteobacteria,1XUJ7@135623|Vibrionales	135623|Vibrionales	M	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
k141_5107_4	1348635.BBJY01000002_gene3590	0.0	884.0	COG0768@1|root,COG0768@2|Bacteria,1MUNY@1224|Proteobacteria,1RNGW@1236|Gammaproteobacteria,1XTH5@135623|Vibrionales	135623|Vibrionales	D	Catalyzes cross-linking of the peptidoglycan cell wall at the division septum	ftsI	-	3.4.16.4	ko:K03587	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PBP_dimer,Transpeptidase
k141_5107_5	1348635.BBJY01000002_gene3591	4.66e-43	143.0	COG3116@1|root,COG3116@2|Bacteria,1N9MH@1224|Proteobacteria,1SC7P@1236|Gammaproteobacteria,1XXXH@135623|Vibrionales	135623|Vibrionales	D	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic	ftsL	-	-	ko:K03586	-	-	-	-	ko00000,ko03036	-	-	-	FtsL
k141_1705_1	1219076.N646_4093	7.1e-141	407.0	COG1609@1|root,COG1609@2|Bacteria,1MVUR@1224|Proteobacteria,1RN2K@1236|Gammaproteobacteria,1XTVU@135623|Vibrionales	135623|Vibrionales	K	Ribose operon repressor	rbsR	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
k141_1705_2	1484158.PSNIH1_06050	3.4e-55	188.0	COG0657@1|root,COG0657@2|Bacteria,1PGCY@1224|Proteobacteria,1RW6K@1236|Gammaproteobacteria,3W1PW@53335|Pantoea	1236|Gammaproteobacteria	I	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S9
k141_1705_3	1410618.JNKI01000035_gene2043	6.06e-109	333.0	COG3203@1|root,COG3203@2|Bacteria,1V0I8@1239|Firmicutes,4H3D3@909932|Negativicutes	909932|Negativicutes	M	S-layer homology domain	-	-	-	-	-	-	-	-	-	-	-	-	SLH
k141_4090_1	314264.ROS217_19887	5.24e-14	70.9	COG2249@1|root,COG2249@2|Bacteria,1MUHN@1224|Proteobacteria,2U15Z@28211|Alphaproteobacteria,46RR2@74030|Roseovarius	28211|Alphaproteobacteria	S	NADPH-quinone reductase (modulator of drug activity B)	-	-	1.6.5.2	ko:K00355	ko00130,ko01110,ko05200,ko05225,ko05418,map00130,map01110,map05200,map05225,map05418	-	R02964,R03643,R03816	RC00819	ko00000,ko00001,ko01000	-	-	-	Flavodoxin_2
k141_4090_2	765912.Thimo_0365	2.04e-161	455.0	COG2267@1|root,COG2267@2|Bacteria,1QUAA@1224|Proteobacteria,1T1RD@1236|Gammaproteobacteria,1WYZI@135613|Chromatiales	135613|Chromatiales	I	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
k141_3064_1	243365.CV_4024	2.76e-68	214.0	COG0110@1|root,COG0110@2|Bacteria,1MUCJ@1224|Proteobacteria,2VVR8@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Bacterial transferase hexapeptide (six repeats)	-	-	2.3.1.79	ko:K00661	-	-	-	-	ko00000,ko01000	-	-	-	Hexapep
k141_3064_2	243365.CV_4023	5.3e-91	281.0	COG2348@1|root,COG2348@2|Bacteria,1NFZI@1224|Proteobacteria	1224|Proteobacteria	V	FemAB family	-	-	-	-	-	-	-	-	-	-	-	-	FemAB
k141_2383_2	517418.Ctha_0980	1.83e-28	112.0	COG0791@1|root,COG0791@2|Bacteria,1FE86@1090|Chlorobi	1090|Chlorobi	M	PFAM NLP P60 protein	-	-	3.4.17.13	ko:K13694	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	NLPC_P60
k141_2383_3	745411.B3C1_10787	0.0	1116.0	COG4953@1|root,COG4953@2|Bacteria,1MUA9@1224|Proteobacteria,1RMBV@1236|Gammaproteobacteria,1J87I@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	Penicillin binding protein transpeptidase domain	pbpC	-	2.4.1.129	ko:K05367	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	BiPBP_C,Transgly,Transpeptidase
k141_2383_4	1236541.BALL01000060_gene4588	2.98e-269	750.0	COG2373@1|root,COG2373@2|Bacteria,1MV7J@1224|Proteobacteria,1RNRY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	Large extracellular alpha-helical protein	-	-	-	ko:K06894	-	-	-	-	ko00000	-	-	-	A2M,A2M_N,A2M_N_2,MG1,Thiol-ester_cl
k141_9_1	555779.Dthio_PD0869	4.7e-42	166.0	COG1452@1|root,COG1452@2|Bacteria,1MUJC@1224|Proteobacteria,42N34@68525|delta/epsilon subdivisions,2WJUD@28221|Deltaproteobacteria,2M86B@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane	lptD	-	-	ko:K04744	-	-	-	-	ko00000,ko02000	1.B.42.1	-	iAF987.Gmet_2474	OstA,OstA_2,OstA_C
k141_3749_1	96561.Dole_1850	2.88e-125	365.0	COG0332@1|root,COG0332@2|Bacteria,1MU9N@1224|Proteobacteria,42MU6@68525|delta/epsilon subdivisions,2WIJN@28221|Deltaproteobacteria,2MJ0P@213118|Desulfobacterales	28221|Deltaproteobacteria	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
k141_4091_2	1235815.BAIX01000090_gene2590	5.57e-51	177.0	COG3344@1|root,COG3344@2|Bacteria,4NGGU@976|Bacteroidetes,2FQ8T@200643|Bacteroidia	976|Bacteroidetes	L	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	2.7.7.49	ko:K00986	-	-	-	-	ko00000,ko01000	-	-	-	GIIM,HNH,RVT_1,RVT_N
k141_4768_1	1123326.JFBL01000004_gene2115	6.43e-175	508.0	COG0367@1|root,COG0367@2|Bacteria,1MW4E@1224|Proteobacteria,42MEI@68525|delta/epsilon subdivisions,2YND5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	asparagine	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
k141_3065_1	56110.Oscil6304_3386	1.63e-42	164.0	COG0515@1|root,COG0642@1|root,COG2199@1|root,COG2203@1|root,COG3899@1|root,COG0515@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,COG3706@2|Bacteria,COG3899@2|Bacteria,1GBKM@1117|Cyanobacteria,1H7D9@1150|Oscillatoriales	2|Bacteria	KLT	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	hstK	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GAF,GAF_2,GGDEF,Guanylate_cyc,HATPase_c,HisKA,PAS_9,Pkinase,Response_reg,SpoIIE
k141_3751_1	439235.Dalk_1286	1.02e-37	143.0	COG3290@1|root,COG3829@1|root,COG3290@2|Bacteria,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,42N7Y@68525|delta/epsilon subdivisions,2WIX7@28221|Deltaproteobacteria,2MI5M@213118|Desulfobacterales	28221|Deltaproteobacteria	KT	Sigma-54 interaction domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,HTH_8,PAS,PAS_8,PAS_9,Sigma54_activat
k141_1022_2	1348635.BBJY01000004_gene2906	1.2e-181	508.0	COG0580@1|root,COG0580@2|Bacteria,1MXTJ@1224|Proteobacteria,1RP2X@1236|Gammaproteobacteria,1XUR2@135623|Vibrionales	135623|Vibrionales	U	Belongs to the MIP aquaporin (TC 1.A.8) family	glpF	-	-	ko:K02440	-	-	-	-	ko00000,ko02000	1.A.8.1,1.A.8.2	-	-	MIP
k141_1022_3	1348635.BBJY01000004_gene2907	5.13e-150	425.0	COG1349@1|root,COG1349@2|Bacteria,1MUJG@1224|Proteobacteria,1RPS0@1236|Gammaproteobacteria,1XSYQ@135623|Vibrionales	135623|Vibrionales	K	COG1349 Transcriptional regulators of sugar metabolism	glpR	-	-	ko:K02444	-	-	-	-	ko00000,ko03000	-	-	-	DeoRC,HTH_DeoR
k141_1022_4	1348635.BBJY01000004_gene2908	0.0	924.0	COG0578@1|root,COG0578@2|Bacteria,1MUMY@1224|Proteobacteria,1RUEK@1236|Gammaproteobacteria,1XUX2@135623|Vibrionales	135623|Vibrionales	C	BFD-like [2Fe-2S] binding domain	glpA	-	1.1.5.3	ko:K00111	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	DAO,Fer2_BFD
k141_1022_5	1348635.BBJY01000004_gene2909	2.24e-210	594.0	COG3075@1|root,COG3075@2|Bacteria,1MU3K@1224|Proteobacteria,1RP77@1236|Gammaproteobacteria,1XSPN@135623|Vibrionales	135623|Vibrionales	C	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor	glpB	GO:0003674,GO:0003824,GO:0004368,GO:0006091,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015980,GO:0016491,GO:0016614,GO:0016901,GO:0044237,GO:0045333,GO:0055114	1.1.5.3	ko:K00112	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	FAD_binding_2
k141_1022_6	1348635.BBJY01000004_gene2910	5.8e-264	727.0	COG0247@1|root,COG0247@2|Bacteria,1MWTK@1224|Proteobacteria,1RQ9M@1236|Gammaproteobacteria,1XVAW@135623|Vibrionales	135623|Vibrionales	C	Cysteine-rich domain	glpC	-	1.1.5.3	ko:K00113	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	CCG,Fer4_8
k141_1022_8	406817.XNC1_3909	1.89e-130	381.0	COG0837@1|root,COG0837@2|Bacteria,1MVFI@1224|Proteobacteria,1RNUY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	F	Belongs to the bacterial glucokinase family	glk	GO:0003674,GO:0003824,GO:0004340,GO:0004396,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019200,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046835,GO:0046939,GO:0051156,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	iNRG857_1313.NRG857_12000	Glucokinase
k141_1022_9	345073.VC395_A0688	2.95e-89	265.0	COG0566@1|root,COG0566@2|Bacteria,1REIN@1224|Proteobacteria,1S48A@1236|Gammaproteobacteria,1XWMC@135623|Vibrionales	135623|Vibrionales	J	SpoU rRNA Methylase family	-	-	-	-	-	-	-	-	-	-	-	-	SpoU_methylase
k141_1022_11	1116375.VEJY3_22581	4.4e-70	232.0	COG3345@1|root,COG3345@2|Bacteria,1MWTQ@1224|Proteobacteria,1RQ4M@1236|Gammaproteobacteria,1XUYH@135623|Vibrionales	135623|Vibrionales	G	COG3345 Alpha-galactosidase	-	-	3.2.1.22	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	-	R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091	RC00049,RC00059,RC00451	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_36C,Glyco_hydro_36N,Melibiase
k141_10_1	1304885.AUEY01000055_gene191	4.27e-193	554.0	COG0076@1|root,COG0076@2|Bacteria,1MWUX@1224|Proteobacteria,42MYA@68525|delta/epsilon subdivisions,2WKFB@28221|Deltaproteobacteria,2MIHP@213118|Desulfobacterales	28221|Deltaproteobacteria	E	PFAM Pyridoxal-dependent decarboxylase	-	-	4.1.1.15	ko:K01580	ko00250,ko00410,ko00430,ko00650,ko01100,ko01110,ko01120,ko02024,ko04727,ko04940,map00250,map00410,map00430,map00650,map01100,map01110,map01120,map02024,map04727,map04940	M00027	R00261,R00489,R01682,R02466	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	EF-hand_7,Pyridoxal_deC
k141_2045_1	675806.VII_001901	3.16e-182	529.0	COG0466@1|root,COG0466@2|Bacteria,1MUV2@1224|Proteobacteria,1RPCB@1236|Gammaproteobacteria,1XU6N@135623|Vibrionales	135623|Vibrionales	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
k141_2045_2	55601.VANGNB10_cI0984	5.85e-50	159.0	COG0776@1|root,COG0776@2|Bacteria,1MZ5B@1224|Proteobacteria,1S8VH@1236|Gammaproteobacteria,1XXU2@135623|Vibrionales	135623|Vibrionales	L	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions	hupB	GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005694,GO:0005737,GO:0005829,GO:0006323,GO:0006996,GO:0008150,GO:0009889,GO:0009987,GO:0010556,GO:0016043,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0051276,GO:0060255,GO:0065007,GO:0071103,GO:0071840,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2001141	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
k141_2045_3	1517681.HW45_22700	2.25e-222	638.0	COG0760@1|root,COG0760@2|Bacteria,1MWV0@1224|Proteobacteria,1RMT5@1236|Gammaproteobacteria,1XT2A@135623|Vibrionales	135623|Vibrionales	O	Peptidylprolyl isomerase	ppiD	-	5.2.1.8	ko:K03770	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase_2,Rotamase_3,SurA_N_3
k141_2045_4	471875.RUMLAC_00585	2.9e-09	59.7	COG1555@1|root,COG1555@2|Bacteria,1VA3W@1239|Firmicutes,24MQF@186801|Clostridia,3WM12@541000|Ruminococcaceae	186801|Clostridia	L	TIGRFAM competence protein ComEA helix-hairpin-helix repeat	comEA	-	-	ko:K02237	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	HHH_3,SLBB
k141_2045_5	674977.VMC_20470	7.55e-125	360.0	COG0283@1|root,COG0283@2|Bacteria,1MUUD@1224|Proteobacteria,1RNKT@1236|Gammaproteobacteria,1XSRV@135623|Vibrionales	135623|Vibrionales	F	Belongs to the cytidylate kinase family. Type 1 subfamily	cmk	GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0015949,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin
k141_2045_6	55601.VANGNB10_cI0988	3.78e-276	763.0	COG0539@1|root,COG0539@2|Bacteria,1MVAV@1224|Proteobacteria,1RMFY@1236|Gammaproteobacteria,1XSTZ@135623|Vibrionales	135623|Vibrionales	J	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence	rpsA	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
k141_5108_1	870967.VIS19158_02490	2.28e-26	100.0	29Y91@1|root,30K2T@2|Bacteria,1R1WH@1224|Proteobacteria,1T5CH@1236|Gammaproteobacteria,1XYQ8@135623|Vibrionales	135623|Vibrionales	S	Phage protein GP46	-	-	-	-	-	-	-	-	-	-	-	-	GP46
k141_5108_2	870967.VIS19158_02495	1.43e-188	531.0	COG3299@1|root,COG3299@2|Bacteria,1QRA6@1224|Proteobacteria,1RU77@1236|Gammaproteobacteria,1XWKZ@135623|Vibrionales	135623|Vibrionales	S	Baseplate J-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Baseplate_J
k141_5108_3	870967.VIS19158_02500	1.22e-48	162.0	2BMJN@1|root,32G4K@2|Bacteria,1QKE8@1224|Proteobacteria,1TII6@1236|Gammaproteobacteria,1XZ6D@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_5108_4	1348635.BBJY01000007_gene151	2.59e-84	268.0	COG5301@1|root,COG5301@2|Bacteria	2|Bacteria	G	cellulose 1,4-beta-cellobiosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF3751
k141_5108_5	1348635.BBJY01000007_gene150	1.22e-76	234.0	2C4D7@1|root,32RDR@2|Bacteria,1QK93@1224|Proteobacteria,1TICI@1236|Gammaproteobacteria,1XYVF@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_5108_6	675815.VOA_001666	3.19e-20	82.8	2BUIT@1|root,32PV5@2|Bacteria,1QMM9@1224|Proteobacteria,1TJWT@1236|Gammaproteobacteria,1Y1SP@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_4093_1	177437.HRM2_21590	1.89e-30	117.0	COG0115@1|root,COG0115@2|Bacteria,1MVAT@1224|Proteobacteria,42PGE@68525|delta/epsilon subdivisions,2WQTM@28221|Deltaproteobacteria	28221|Deltaproteobacteria	EH	Amino-transferase class IV	-	-	2.6.1.21	ko:K00824	ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100	-	R01148,R01582,R02459,R02851,R02924,R05053	RC00006,RC00008,RC00025	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_4
k141_4093_2	557598.LHK_00359	1.09e-17	85.9	COG0045@1|root,COG0454@1|root,COG1042@1|root,COG0045@2|Bacteria,COG0456@2|Bacteria,COG1042@2|Bacteria,1MW98@1224|Proteobacteria,2VI9R@28216|Betaproteobacteria,2KQHX@206351|Neisseriales	206351|Neisseriales	C	CoA binding domain protein	-	-	-	ko:K09181	-	-	-	-	ko00000	-	-	-	ATP-grasp_5,Acetyltransf_1,Acetyltransf_3,Acetyltransf_4,CoA_binding_2,Succ_CoA_lig
k141_4770_2	443254.Marpi_1660	9.69e-23	105.0	COG0641@1|root,COG0641@2|Bacteria,2GDBJ@200918|Thermotogae	200918|Thermotogae	C	PFAM Radical SAM	-	-	-	ko:K06871	-	-	-	-	ko00000	-	-	-	Fer4_12,Radical_SAM
k141_3066_1	386456.JQKN01000009_gene1170	6.75e-30	116.0	COG0500@1|root,arCOG01786@2157|Archaea,2XYF4@28890|Euryarchaeota	28890|Euryarchaeota	Q	PFAM Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
k141_3066_2	1121396.KB893058_gene2572	2.37e-140	419.0	COG1629@1|root,COG4771@2|Bacteria,1MUC1@1224|Proteobacteria,42NGM@68525|delta/epsilon subdivisions,2WKKR@28221|Deltaproteobacteria,2MMH5@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Outer membrane protein beta-barrel family	-	-	-	ko:K16089	-	-	-	-	ko00000,ko02000	1.B.14.1,1.B.14.10	-	-	Plug,TonB_dep_Rec
k141_4431_1	617140.AJZE01000073_gene770	1.15e-29	117.0	COG4776@1|root,COG4776@2|Bacteria,1P563@1224|Proteobacteria,1RP5G@1236|Gammaproteobacteria,1XSNX@135623|Vibrionales	135623|Vibrionales	J	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction	rnb	GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0008859,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0140098,GO:1901360,GO:1901361,GO:1901575	3.1.13.1	ko:K01147	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	OB_RNB,RNB,S1
k141_4431_2	243277.VC_A0806	4.62e-42	142.0	2AWCE@1|root,31N87@2|Bacteria,1QJZK@1224|Proteobacteria,1TI21@1236|Gammaproteobacteria,1XY73@135623|Vibrionales	135623|Vibrionales	S	Protein of unknown function (DUF3024)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3024
k141_4431_3	1051646.VITU9109_07528	1.95e-116	343.0	COG0226@1|root,COG0226@2|Bacteria,1MW2Z@1224|Proteobacteria,1S5B9@1236|Gammaproteobacteria,1XTQY@135623|Vibrionales	135623|Vibrionales	P	COG0226 ABC-type phosphate transport system, periplasmic component	-	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like,PBP_like_2
k141_4431_4	1123366.TH3_15214	7.32e-198	553.0	COG2515@1|root,COG2515@2|Bacteria,1MVYF@1224|Proteobacteria,2TRCB@28211|Alphaproteobacteria,2JQCF@204441|Rhodospirillales	204441|Rhodospirillales	E	Catalyzes a cyclopropane ring-opening reaction, the irreversible conversion of 1-aminocyclopropane-1-carboxylate (ACC) to ammonia and alpha-ketobutyrate. Allows growth on ACC as a nitrogen source	acdS	-	3.5.99.7	ko:K01505	ko00270,map00270	-	R00997	RC00419	ko00000,ko00001,ko01000	-	-	-	PALP
k141_4431_5	460265.Mnod_5478	1.85e-67	209.0	COG1522@1|root,COG1522@2|Bacteria,1RB37@1224|Proteobacteria,2U3NJ@28211|Alphaproteobacteria,1JSH3@119045|Methylobacteriaceae	28211|Alphaproteobacteria	K	PFAM regulatory protein AsnC Lrp family	MA20_39555	-	-	ko:K03719	-	-	-	-	ko00000,ko03000,ko03036	-	-	-	AsnC_trans_reg,HTH_24,HTH_AsnC-type
k141_2046_1	870967.VIS19158_20696	5.8e-126	365.0	COG1434@1|root,COG1434@2|Bacteria,1MVW8@1224|Proteobacteria,1RNZC@1236|Gammaproteobacteria,1XUG3@135623|Vibrionales	135623|Vibrionales	S	DUF218 domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF218
k141_5109_1	1121918.ARWE01000001_gene3148	4.72e-73	236.0	2CFUQ@1|root,2ZC1I@2|Bacteria,1RBHI@1224|Proteobacteria,42QR4@68525|delta/epsilon subdivisions,2WMXI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_5109_2	1499967.BAYZ01000118_gene3302	1.67e-27	108.0	COG0697@1|root,COG0697@2|Bacteria,2NRS8@2323|unclassified Bacteria	2|Bacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
k141_3067_1	1121396.KB893077_gene739	1.48e-120	355.0	COG0438@1|root,COG0662@1|root,COG0438@2|Bacteria,COG0662@2|Bacteria,1MWSZ@1224|Proteobacteria,42NYZ@68525|delta/epsilon subdivisions,2WK9U@28221|Deltaproteobacteria,2MMTM@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1,MannoseP_isomer
k141_1023_1	469595.CSAG_01836	1.88e-49	169.0	COG2099@1|root,COG2099@2|Bacteria,1MW48@1224|Proteobacteria,1S0P4@1236|Gammaproteobacteria,3WVKP@544|Citrobacter	1236|Gammaproteobacteria	H	Precorrin-6x reductase CbiJ/CobK	cobK	-	1.3.1.106,1.3.1.54	ko:K05895	ko00860,ko01100,map00860,map01100	-	R05150,R05812	RC01280	ko00000,ko00001,ko01000	-	-	-	CbiJ
k141_1023_2	595494.Tola_1673	1.76e-135	387.0	COG1010@1|root,COG1010@2|Bacteria,1MU79@1224|Proteobacteria,1RPC2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	H	precorrin-3B C17-methyltransferase	cbiH	-	2.1.1.131	ko:K05934	ko00860,ko01100,map00860,map01100	-	R05180,R05809	RC00003,RC01293,RC03471	ko00000,ko00001,ko01000	-	-	-	TP_methylase
k141_1023_3	595494.Tola_1674	1e-115	347.0	COG2073@1|root,COG2073@2|Bacteria,1MWE6@1224|Proteobacteria,1RPWK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	H	Cobalamin biosynthesis protein CbiG	cbiG	-	3.7.1.12	ko:K02189	ko00860,ko01100,map00860,map01100	-	R07772	RC01545,RC02097	ko00000,ko00001,ko01000	-	-	-	CbiG_C,CbiG_N,CbiG_mid
k141_1023_4	1006004.GBAG_2567	9.08e-47	157.0	COG2875@1|root,COG2875@2|Bacteria,1MVYY@1224|Proteobacteria,1RWPQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	H	Precorrin-4 C(11)-methyltransferase	cobM	-	2.1.1.133,2.1.1.271	ko:K05936	ko00860,ko01100,map00860,map01100	-	R05181,R05810	RC00003,RC01294,RC02049	ko00000,ko00001,ko01000	-	-	-	TP_methylase
k141_4432_1	572480.Arnit_1442	4.26e-32	118.0	COG0662@1|root,COG0662@2|Bacteria,1N3UA@1224|Proteobacteria,42U03@68525|delta/epsilon subdivisions,2YPCC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
k141_4432_2	1112217.PPL19_09541	9.19e-35	128.0	COG1309@1|root,COG1309@2|Bacteria,1N1Q3@1224|Proteobacteria,1S6W5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	transcriptional regulator	-	-	-	ko:K16137	-	-	-	-	ko00000,ko03000	-	-	-	TetR_N
k141_3068_1	1123518.ARWI01000001_gene232	3.36e-124	356.0	COG0110@1|root,COG0110@2|Bacteria,1MUCJ@1224|Proteobacteria,1RPPT@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	COG0110 Acetyltransferase (isoleucine patch superfamily)	sat	-	-	ko:K18234	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	Hexapep
k141_4094_1	555079.Toce_0946	1.98e-84	282.0	COG0768@1|root,COG2815@1|root,COG0768@2|Bacteria,COG2815@2|Bacteria,1TP93@1239|Firmicutes,248KB@186801|Clostridia,42FD0@68295|Thermoanaerobacterales	186801|Clostridia	M	TIGRFAM stage V sporulation protein D	spoVD	-	3.4.16.4	ko:K03587,ko:K08384	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PASTA,PBP_dimer,Transpeptidase
k141_686_1	345073.VC395_0442	2.2e-154	457.0	COG2199@1|root,COG2200@1|root,COG2199@2|Bacteria,COG2200@2|Bacteria,1MUQV@1224|Proteobacteria,1RN0Q@1236|Gammaproteobacteria,1XSFU@135623|Vibrionales	135623|Vibrionales	T	COG2199 FOG GGDEF domain	csrD	-	-	ko:K18765	-	-	-	-	ko00000,ko03019	-	-	-	EAL,GAPES4,GGDEF
k141_686_2	243277.VC_0415	8.75e-237	652.0	COG1077@1|root,COG1077@2|Bacteria,1MUMW@1224|Proteobacteria,1RN82@1236|Gammaproteobacteria,1XSBK@135623|Vibrionales	135623|Vibrionales	D	Rod shape-determining protein MreB	mreB	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
k141_686_4	345073.VC395_0461	3.27e-88	261.0	COG2891@1|root,COG2891@2|Bacteria,1RER7@1224|Proteobacteria,1S4DE@1236|Gammaproteobacteria,1XTT8@135623|Vibrionales	135623|Vibrionales	M	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins	mreD	-	-	ko:K03571	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreD
k141_686_5	243277.VC_0418	4.11e-72	223.0	COG0424@1|root,COG0424@2|Bacteria,1RH6H@1224|Proteobacteria,1S41D@1236|Gammaproteobacteria,1XVZI@135623|Vibrionales	135623|Vibrionales	D	COG0424 Nucleotide-binding protein implicated in inhibition of septum formation	maf	-	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
k141_4771_1	1348635.BBJY01000002_gene3559	2.26e-181	531.0	COG0642@1|root,COG0784@1|root,COG2198@1|root,COG0784@2|Bacteria,COG2198@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,1SKTW@1236|Gammaproteobacteria,1XSC0@135623|Vibrionales	135623|Vibrionales	T	aerobic respiration control sensor protein	arcB	-	2.7.13.3	ko:K07648	ko02020,ko02026,map02020,map02026	M00456	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,Hpt,PAS,PAS_4,Response_reg
k141_5110_1	1121396.KB892902_gene2341	3.13e-17	79.7	COG0138@1|root,COG0138@2|Bacteria,1MUDQ@1224|Proteobacteria,42MV4@68525|delta/epsilon subdivisions,2WKHZ@28221|Deltaproteobacteria,2MI2I@213118|Desulfobacterales	28221|Deltaproteobacteria	F	PFAM AICARFT IMPCHase bienzyme	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
k141_5110_2	592031.GCWU000322_00408	8e-07	54.7	COG0484@1|root,COG0484@2|Bacteria,1TP00@1239|Firmicutes,248EM@186801|Clostridia,25UX4@186806|Eubacteriaceae	186801|Clostridia	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686,ko:K05516	-	-	-	-	ko00000,ko03029,ko03036,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
k141_5110_3	1454004.AW11_02552	2.54e-88	269.0	COG1192@1|root,COG1192@2|Bacteria,1MVEZ@1224|Proteobacteria,2VK7W@28216|Betaproteobacteria	28216|Betaproteobacteria	D	Cobyrinic acid ac-diamide synthase	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
k141_13_2	1348635.BBJY01000005_gene3364	5.33e-60	190.0	2BIEI@1|root,32CKV@2|Bacteria,1PR7U@1224|Proteobacteria,1RUV9@1236|Gammaproteobacteria,1XZG1@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_13_3	1348635.BBJY01000005_gene3365	7.35e-31	112.0	2AXCV@1|root,31PC6@2|Bacteria,1QM2F@1224|Proteobacteria,1TJ9S@1236|Gammaproteobacteria,1Y0V9@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_13_4	1348635.BBJY01000005_gene3366	4.41e-216	601.0	COG0582@1|root,COG0582@2|Bacteria,1MVZB@1224|Proteobacteria,1RP4Y@1236|Gammaproteobacteria,1XWHJ@135623|Vibrionales	135623|Vibrionales	L	Belongs to the 'phage' integrase family	-	-	-	ko:K14059	-	-	-	-	ko00000	-	-	-	Arm-DNA-bind_2,Phage_int_SAM_3,Phage_integrase
k141_3069_1	1304885.AUEY01000050_gene1194	2.9e-81	250.0	COG0492@1|root,COG0492@2|Bacteria,1MV15@1224|Proteobacteria,42MHR@68525|delta/epsilon subdivisions,2WIY8@28221|Deltaproteobacteria,2MJC5@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Pyridine nucleotide-disulphide oxidoreductase	trxB	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
k141_4772_1	1265505.ATUG01000001_gene4555	1.29e-117	355.0	28I8B@1|root,2Z8B5@2|Bacteria,1MUNM@1224|Proteobacteria,42NZH@68525|delta/epsilon subdivisions,2WKHB@28221|Deltaproteobacteria,2MISZ@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM Cytochrome c, bacterial	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_CIII,Cytochrome_C554,Cytochrome_cB
k141_2725_25	485916.Dtox_2342	1.06e-41	155.0	COG5184@1|root,COG5492@1|root,COG5184@2|Bacteria,COG5492@2|Bacteria,1VG2U@1239|Firmicutes,24JBU@186801|Clostridia,265E6@186807|Peptococcaceae	186801|Clostridia	DNZ	PFAM coagulation factor 5 8 type domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CW_binding_1,Cadherin-like,F5_F8_type_C
k141_2725_26	562970.Btus_1884	3.46e-33	149.0	COG5184@1|root,COG5184@2|Bacteria,1UM5S@1239|Firmicutes,4ITQP@91061|Bacilli,279WZ@186823|Alicyclobacillaceae	91061|Bacilli	DMZ	Cadherin-like beta sandwich domain	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin-like,SLH
k141_754_19	345073.VC395_1640	7.62e-186	549.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,1RQZD@1236|Gammaproteobacteria,1XU16@135623|Vibrionales	135623|Vibrionales	T	COG0642 Signal transduction histidine kinase	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,sCache_3_3
k141_754_20	1238450.VIBNISOn1_500001	2.75e-178	516.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria,1XTA5@135623|Vibrionales	135623|Vibrionales	T	COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
k141_754_21	1191299.AJYX01000087_gene3065	6.25e-54	177.0	COG0746@1|root,COG0746@2|Bacteria,1RH3M@1224|Proteobacteria,1S74N@1236|Gammaproteobacteria,1XSWW@135623|Vibrionales	135623|Vibrionales	H	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor	mobA	GO:0003674,GO:0003824,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0071704,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.7.77	ko:K03752	ko00790,ko01100,map00790,map01100	-	R11581	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
k141_754_22	675817.VDA_002164	6.44e-45	172.0	COG0303@1|root,COG1763@1|root,COG0303@2|Bacteria,COG1763@2|Bacteria,1MVD5@1224|Proteobacteria,1RMQU@1236|Gammaproteobacteria,1XU88@135623|Vibrionales	135623|Vibrionales	H	Molybdopterin-guanine dinucleotide biosynthesis protein	-	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MobB,MoeA_C,MoeA_N
k141_754_23	675813.VIB_001267	4.9e-39	131.0	2CBU7@1|root,32ZCT@2|Bacteria,1N85K@1224|Proteobacteria,1SCKM@1236|Gammaproteobacteria,1XYDW@135623|Vibrionales	135623|Vibrionales	S	Protein of unknown function (DUF2960)	SO1372	-	-	-	-	-	-	-	-	-	-	-	DUF2960
k141_754_24	1187848.AJYQ01000076_gene1640	8.37e-150	429.0	COG1940@1|root,COG1940@2|Bacteria,1MU94@1224|Proteobacteria,1RNHE@1236|Gammaproteobacteria,1XSU2@135623|Vibrionales	135623|Vibrionales	F	Catalyzes the phosphorylation of N-acetyl-D-glucosamine (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P	nagK	-	2.7.1.59	ko:K00884	ko00520,ko01100,map00520,map01100	-	R01201	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	ROK
k141_754_25	945550.VISI1226_21084	2.03e-101	301.0	COG3148@1|root,COG3148@2|Bacteria,1N8XY@1224|Proteobacteria,1RS6H@1236|Gammaproteobacteria,1XV59@135623|Vibrionales	135623|Vibrionales	S	DTW	-	-	-	ko:K05812	-	-	-	-	ko00000	-	-	-	DTW
k141_754_26	1348635.BBJY01000005_gene3185	1.12e-60	188.0	2B806@1|root,3217S@2|Bacteria,1RHQE@1224|Proteobacteria,1S7AC@1236|Gammaproteobacteria,1XXB8@135623|Vibrionales	135623|Vibrionales	S	COG0187 Type IIA topoisomerase (DNA gyrase topo II, topoisomerase IV), B subunit	SO2891	-	-	-	-	-	-	-	-	-	-	-	DUF3802
k141_754_27	312309.VF_1413	3.23e-107	320.0	COG3001@1|root,COG3001@2|Bacteria,1MVHX@1224|Proteobacteria,1RRC5@1236|Gammaproteobacteria,1XSBA@135623|Vibrionales	135623|Vibrionales	G	COG3001 Fructosamine-3-kinase	-	GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0044237	-	-	-	-	-	-	-	-	-	-	Fructosamin_kin
k141_754_28	945543.VIBR0546_00490	2.82e-95	283.0	COG0307@1|root,COG0307@2|Bacteria,1MUMB@1224|Proteobacteria,1RMSY@1236|Gammaproteobacteria,1XT06@135623|Vibrionales	135623|Vibrionales	H	Riboflavin synthase alpha chain	ribE	-	2.5.1.9	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00066	RC00958,RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	Lum_binding
k141_754_29	945550.VISI1226_21124	8.83e-200	568.0	COG0534@1|root,COG0534@2|Bacteria,1MUAM@1224|Proteobacteria,1RP5M@1236|Gammaproteobacteria,1XUSY@135623|Vibrionales	135623|Vibrionales	V	Multidrug efflux pump	norM	GO:0003674,GO:0005215,GO:0006810,GO:0006855,GO:0008150,GO:0015238,GO:0015893,GO:0022857,GO:0042221,GO:0042493,GO:0042891,GO:0042895,GO:0046677,GO:0050896,GO:0051179,GO:0051234,GO:0055085	-	ko:K03327	-	-	-	-	ko00000,ko02000	2.A.66.1	-	-	MatE
k141_754_30	945550.VISI1226_04270	1.65e-63	200.0	COG3040@1|root,COG3040@2|Bacteria,1RDAI@1224|Proteobacteria,1S4SZ@1236|Gammaproteobacteria,1Y272@135623|Vibrionales	135623|Vibrionales	M	Lipocalin / cytosolic fatty-acid binding protein family	blc	-	-	-	-	-	-	-	-	-	-	-	Lipocalin_2
k141_754_31	1116375.VEJY3_16266	4.4e-169	479.0	COG0039@1|root,COG0039@2|Bacteria,1MV57@1224|Proteobacteria,1RPAX@1236|Gammaproteobacteria,1XWBX@135623|Vibrionales	135623|Vibrionales	C	Belongs to the LDH MDH superfamily	-	-	1.1.1.27	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	-	R00703,R01000,R03104	RC00031,RC00044	ko00000,ko00001,ko01000,ko04147	-	-	-	Ldh_1_C,Ldh_1_N
k141_754_32	674977.VMC_19760	4.34e-56	186.0	2AX9W@1|root,31P8X@2|Bacteria,1QJEF@1224|Proteobacteria,1THDS@1236|Gammaproteobacteria,1XUGM@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_754_33	1219065.VPR01S_01_02500	1.59e-08	52.0	2AWX4@1|root,31NUN@2|Bacteria,1QKIA@1224|Proteobacteria,1TINI@1236|Gammaproteobacteria,1XZDH@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_754_34	1517681.HW45_18095	1.55e-240	671.0	COG1115@1|root,COG1115@2|Bacteria,1MUI3@1224|Proteobacteria,1RMNF@1236|Gammaproteobacteria,1XUBZ@135623|Vibrionales	135623|Vibrionales	U	COG1115 Na alanine symporter	-	-	-	ko:K03310	-	-	-	-	ko00000	2.A.25	-	-	Na_Ala_symp
k141_754_35	1348635.BBJY01000005_gene3267	1.05e-99	295.0	COG1280@1|root,COG1280@2|Bacteria,1RF1D@1224|Proteobacteria,1T02Q@1236|Gammaproteobacteria,1XUXV@135623|Vibrionales	135623|Vibrionales	E	LysE type translocator	-	-	-	-	-	-	-	-	-	-	-	-	LysE
k141_754_36	1123053.AUDG01000004_gene3545	5.97e-37	125.0	2EA3G@1|root,3348H@2|Bacteria,1N89N@1224|Proteobacteria,1SF7H@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Domain of unknown function (DUF4177)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4177
k141_754_37	945543.VIBR0546_12177	6e-33	119.0	2DBBF@1|root,32TX4@2|Bacteria,1N03C@1224|Proteobacteria,1SE8G@1236|Gammaproteobacteria,1XXU4@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_754_38	207954.MED92_14433	0.0	1313.0	COG0204@1|root,COG0318@1|root,COG0477@1|root,COG0204@2|Bacteria,COG0318@2|Bacteria,COG2814@2|Bacteria,1MWDY@1224|Proteobacteria,1RRXF@1236|Gammaproteobacteria,1XIGR@135619|Oceanospirillales	135619|Oceanospirillales	I	Acyltransferase	-	-	2.3.1.40,6.2.1.20	ko:K05939	ko00071,ko00564,map00071,map00564	-	R01406,R04864	RC00014,RC00039,RC00041	ko00000,ko00001,ko01000	-	-	-	AMP-binding,Acyltransferase,MFS_1
k141_754_39	1242864.D187_004082	1.97e-56	196.0	COG0726@1|root,COG0726@2|Bacteria,1PEGX@1224|Proteobacteria,437HX@68525|delta/epsilon subdivisions,2WTK9@28221|Deltaproteobacteria,2Z1M4@29|Myxococcales	28221|Deltaproteobacteria	G	Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
k141_754_40	1236541.BALL01000018_gene2451	1.85e-110	334.0	COG4099@1|root,COG4099@2|Bacteria,1NS63@1224|Proteobacteria,1SMX7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	phospholipase Carboxylesterase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_2
k141_754_41	55601.VANGNB10_cI0615	1.03e-97	302.0	COG0025@1|root,COG1226@1|root,COG0025@2|Bacteria,COG1226@2|Bacteria,1QTUE@1224|Proteobacteria,1T1HJ@1236|Gammaproteobacteria,1XUJX@135623|Vibrionales	135623|Vibrionales	P	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger,TrkA_N
k141_754_42	1348635.BBJY01000008_gene1715	1.99e-178	516.0	COG0025@1|root,COG1226@1|root,COG0025@2|Bacteria,COG1226@2|Bacteria,1QTUE@1224|Proteobacteria,1T1HJ@1236|Gammaproteobacteria,1XUJX@135623|Vibrionales	135623|Vibrionales	P	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger,TrkA_N
k141_754_43	1515746.HR45_03410	3.7e-178	519.0	COG0840@1|root,COG2703@1|root,COG0840@2|Bacteria,COG2703@2|Bacteria,1RBB1@1224|Proteobacteria,1S265@1236|Gammaproteobacteria,2Q9DW@267890|Shewanellaceae	1236|Gammaproteobacteria	NPT	Hemerythrin HHE cation binding domain protein	-	-	-	ko:K07216	-	-	-	-	ko00000	-	-	-	Hemerythrin,MCPsignal
k141_754_44	663610.JQKO01000001_gene899	3.83e-107	320.0	COG1117@1|root,COG1117@2|Bacteria,1MU16@1224|Proteobacteria,2TQX9@28211|Alphaproteobacteria,3N9K7@45404|Beijerinckiaceae	28211|Alphaproteobacteria	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
k141_754_45	305900.GV64_16185	1.19e-124	363.0	COG0581@1|root,COG0581@2|Bacteria,1MUWB@1224|Proteobacteria,1RPV9@1236|Gammaproteobacteria,1XNEB@135619|Oceanospirillales	135619|Oceanospirillales	P	Phosphate transport system permease	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
k141_754_46	1517681.HW45_11705	3.21e-134	390.0	COG0573@1|root,COG0573@2|Bacteria,1MVKP@1224|Proteobacteria,1RQXJ@1236|Gammaproteobacteria,1XVMB@135623|Vibrionales	135623|Vibrionales	P	probably responsible for the translocation of the substrate across the membrane	-	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
k141_754_47	675814.VIC_003317	1.27e-154	443.0	COG0226@1|root,COG0226@2|Bacteria,1MUAZ@1224|Proteobacteria,1RN5Q@1236|Gammaproteobacteria,1XVSF@135623|Vibrionales	135623|Vibrionales	P	Part of the ABC transporter complex PstSACB involved in phosphate import	-	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
k141_1117_1	933262.AXAM01000028_gene3299	1.16e-111	331.0	COG0536@1|root,COG0536@2|Bacteria,1MUGZ@1224|Proteobacteria,42M40@68525|delta/epsilon subdivisions,2WIM4@28221|Deltaproteobacteria,2MI7D@213118|Desulfobacterales	28221|Deltaproteobacteria	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	-	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	GTP1_OBG,MMR_HSR1
k141_1117_2	207559.Dde_2691	1.17e-36	125.0	COG0211@1|root,COG0211@2|Bacteria,1MZGH@1224|Proteobacteria,42THK@68525|delta/epsilon subdivisions,2WQ2U@28221|Deltaproteobacteria,2MCGT@213115|Desulfovibrionales	28221|Deltaproteobacteria	J	Belongs to the bacterial ribosomal protein bL27 family	rpmA	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02899	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27
k141_1117_3	1121405.dsmv_3223	4.03e-13	65.1	COG0261@1|root,COG0261@2|Bacteria,1MZEW@1224|Proteobacteria,42SGM@68525|delta/epsilon subdivisions,2WQ3I@28221|Deltaproteobacteria,2MKN7@213118|Desulfobacterales	28221|Deltaproteobacteria	J	This protein binds to 23S rRNA in the presence of protein L20	rplU	GO:0003674,GO:0003735,GO:0005198	-	ko:K02888	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L21p
k141_4539_1	177437.HRM2_36960	6.5e-52	187.0	COG1256@1|root,COG1256@2|Bacteria,1MV2M@1224|Proteobacteria,42PBN@68525|delta/epsilon subdivisions,2WMU3@28221|Deltaproteobacteria,2MIDK@213118|Desulfobacterales	28221|Deltaproteobacteria	N	TIGRFAM flagellar hook-associated protein FlgK	flgK	-	-	ko:K02396	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod,Flg_bbr_C
k141_1118_1	1121396.KB892990_gene4510	1.28e-110	345.0	COG1033@1|root,COG1033@2|Bacteria,1MUE1@1224|Proteobacteria,42ME2@68525|delta/epsilon subdivisions,2WJRI@28221|Deltaproteobacteria,2MNE6@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Sterol-sensing domain of SREBP cleavage-activation	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
k141_4864_1	1265505.ATUG01000003_gene436	1.74e-159	474.0	COG0550@1|root,COG0550@2|Bacteria,1MUFZ@1224|Proteobacteria,42MM9@68525|delta/epsilon subdivisions,2WJTT@28221|Deltaproteobacteria,2MITA@213118|Desulfobacterales	28221|Deltaproteobacteria	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,zf-C4_Topoisom
k141_4864_2	96561.Dole_2358	1.25e-88	265.0	COG0231@1|root,COG0231@2|Bacteria,1MW2J@1224|Proteobacteria,42N6H@68525|delta/epsilon subdivisions,2WNG7@28221|Deltaproteobacteria,2MHWW@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase	efp	GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
k141_4864_3	192952.MM_2819	1.19e-10	67.8	COG0135@1|root,arCOG01983@2157|Archaea,2XXCM@28890|Euryarchaeota,2NBIJ@224756|Methanomicrobia	224756|Methanomicrobia	E	Belongs to the TrpF family	trpF	-	5.3.1.24	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03509	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	PRAI
k141_4864_5	1265505.ATUG01000001_gene3592	1.31e-80	255.0	COG0438@1|root,COG0438@2|Bacteria,1NA28@1224|Proteobacteria,42NZA@68525|delta/epsilon subdivisions,2WK1T@28221|Deltaproteobacteria,2MIH3@213118|Desulfobacterales	28221|Deltaproteobacteria	M	PFAM Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	DUF3524,Glycos_transf_1
k141_2114_1	1304888.ATWF01000001_gene991	8.97e-67	217.0	COG0697@1|root,COG0697@2|Bacteria,2GFKH@200930|Deferribacteres	200930|Deferribacteres	EG	EamA-like transporter family	-	-	-	ko:K03298	-	-	-	-	ko00000,ko02000	2.A.7.3	-	-	EamA
k141_2114_2	1219080.VEZ01S_54_00070	1.72e-17	85.5	COG1988@1|root,COG1988@2|Bacteria,1MZEI@1224|Proteobacteria,1S9P5@1236|Gammaproteobacteria,1XWH2@135623|Vibrionales	135623|Vibrionales	S	LexA-binding, inner membrane-associated putative hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	YdjM
k141_1458_1	1283284.AZUK01000001_gene2537	5.73e-05	44.3	COG1309@1|root,COG1309@2|Bacteria,1MZ9E@1224|Proteobacteria,1S5F3@1236|Gammaproteobacteria,1Y66E@135624|Aeromonadales	135624|Aeromonadales	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_7,TetR_N
k141_1458_2	595494.Tola_1031	9.85e-196	560.0	COG1538@1|root,COG1538@2|Bacteria,1MUZZ@1224|Proteobacteria,1RQEP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	MU	RND efflux system, outer membrane lipoprotein	mdtP	-	-	-	-	-	-	-	-	-	-	-	OEP
k141_1458_3	29495.EA26_16390	1.94e-23	99.0	COG1566@1|root,COG1566@2|Bacteria,1MU7I@1224|Proteobacteria,1RMAD@1236|Gammaproteobacteria,1XW5D@135623|Vibrionales	135623|Vibrionales	V	COG1566 Multidrug resistance efflux pump	-	-	-	ko:K03543	-	M00701	-	-	ko00000,ko00002,ko02000	8.A.1.1	-	-	Biotin_lipoyl_2,HlyD,HlyD_3,HlyD_D23
k141_4558_3	55601.VANGNB10_cI1506	3.42e-24	93.6	2B5HC@1|root,31YC1@2|Bacteria,1QKAU@1224|Proteobacteria,1TIEB@1236|Gammaproteobacteria,1XYZ4@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_4558_4	1219077.VAZ01S_008_00280	4.19e-39	134.0	COG0645@1|root,COG0645@2|Bacteria,1N1S8@1224|Proteobacteria,1SEDC@1236|Gammaproteobacteria,1XXSN@135623|Vibrionales	135623|Vibrionales	S	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_33
k141_4558_5	1051646.VITU9109_12018	1.27e-187	525.0	COG1897@1|root,COG1897@2|Bacteria,1MV64@1224|Proteobacteria,1RM7T@1236|Gammaproteobacteria,1XTIN@135623|Vibrionales	135623|Vibrionales	E	Transfers a succinyl group from succinyl-CoA to L- homoserine, forming succinyl-L-homoserine	metAS	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0008899,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0016748,GO:0016750,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.3.1.46	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	M00017	R01777	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	HTS
k141_4558_6	1283284.AZUK01000001_gene2382	7.61e-29	115.0	COG3063@1|root,COG3063@2|Bacteria,1MXPC@1224|Proteobacteria,1RY78@1236|Gammaproteobacteria,1Y4HS@135624|Aeromonadales	135624|Aeromonadales	NU	type IV pilus biogenesis stability protein PilW	-	-	-	ko:K02656	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	TPR_12,TPR_19,TPR_8
k141_4558_7	345073.VC395_1729	6.4e-15	69.7	2AWKY@1|root,31NHP@2|Bacteria,1QK8G@1224|Proteobacteria,1TIBY@1236|Gammaproteobacteria,1XYUB@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_4558_8	945543.VIBR0546_13272	5.01e-61	189.0	2E73W@1|root,331NB@2|Bacteria,1N81U@1224|Proteobacteria,1SCT8@1236|Gammaproteobacteria,1XXHR@135623|Vibrionales	135623|Vibrionales	S	Protein of unknown function (DUF2750)	SO1991	-	-	-	-	-	-	-	-	-	-	-	DUF2750
k141_4558_9	1280001.BAOA01000019_gene499	1.53e-98	290.0	2EYK5@1|root,33RTU@2|Bacteria,1NQK6@1224|Proteobacteria,1SKUJ@1236|Gammaproteobacteria,1XSV5@135623|Vibrionales	135623|Vibrionales	S	Phosphoribosyl-ATP pyrophosphohydrolase	VP1313	-	-	-	-	-	-	-	-	-	-	-	PRA-PH
k141_4558_10	243277.VC_1240	6.83e-54	177.0	COG0406@1|root,COG0406@2|Bacteria,1RHAT@1224|Proteobacteria,1S69R@1236|Gammaproteobacteria,1XWM4@135623|Vibrionales	135623|Vibrionales	G	COG0406 Fructose-2,6-bisphosphatase	cobC	-	3.1.3.73	ko:K02226	ko00860,ko01100,map00860,map01100	M00122	R04594,R11173	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	His_Phos_1
k141_4558_11	675815.VOA_000383	7.66e-63	199.0	COG2087@1|root,COG2087@2|Bacteria,1RH0A@1224|Proteobacteria,1S42M@1236|Gammaproteobacteria,1XXMV@135623|Vibrionales	135623|Vibrionales	H	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate	cobU	-	2.7.1.156,2.7.7.62	ko:K02231	ko00860,ko01100,map00860,map01100	M00122	R05221,R05222,R06558	RC00002,RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	CobU
k141_4558_12	1517681.HW45_18160	2.73e-244	681.0	COG2925@1|root,COG2925@2|Bacteria,1MV0U@1224|Proteobacteria,1RM85@1236|Gammaproteobacteria,1XT1P@135623|Vibrionales	135623|Vibrionales	L	COG2925 Exonuclease I	sbcB	-	3.1.11.1	ko:K01141	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_X-T_C,RNase_T
k141_4558_13	394503.Ccel_1414	0.000627	42.4	COG1380@1|root,COG1380@2|Bacteria,1VEN4@1239|Firmicutes,24MMB@186801|Clostridia,36KP1@31979|Clostridiaceae	186801|Clostridia	S	LrgA family	lrgA	-	-	ko:K06518	-	-	-	-	ko00000,ko02000	1.E.14.2	-	-	LrgA
k141_3163_1	572477.Alvin_1578	4.48e-59	218.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,1WXS9@135613|Chromatiales	135613|Chromatiales	NT	PFAM Methyl-accepting chemotaxis protein (MCP) signaling domain	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HBM,MCPsignal
k141_3163_2	177439.DP2388	1.66e-26	102.0	COG0801@1|root,COG0801@2|Bacteria,1NP9D@1224|Proteobacteria,42XAD@68525|delta/epsilon subdivisions,2WTBA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Putative redox-active protein (C_GCAxxG_C_C)	-	-	-	-	-	-	-	-	-	-	-	-	C_GCAxxG_C_C
k141_3163_3	582744.Msip34_1572	2.67e-57	214.0	COG0840@1|root,COG2770@1|root,COG0840@2|Bacteria,COG2770@2|Bacteria,1MU9B@1224|Proteobacteria,2VGZ8@28216|Betaproteobacteria,2KP49@206350|Nitrosomonadales	206350|Nitrosomonadales	NT	histidine kinase HAMP region domain protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal,dCache_1
k141_1826_1	411459.RUMOBE_03485	7.43e-13	75.1	COG2703@1|root,COG2703@2|Bacteria,1VAI0@1239|Firmicutes,24MQU@186801|Clostridia,3XZZH@572511|Blautia	186801|Clostridia	P	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K07216	-	-	-	-	ko00000	-	-	-	Hemerythrin
k141_1146_1	675813.VIB_002705	1.15e-116	354.0	COG1109@1|root,COG1109@2|Bacteria,1QUGD@1224|Proteobacteria,1RQME@1236|Gammaproteobacteria,1XVES@135623|Vibrionales	135623|Vibrionales	G	Phosphoglucomutase phosphomannomutase alpha beta subunit	-	-	5.4.2.8	ko:K01840	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01818	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
k141_1146_2	1188252.AJYK01000082_gene1182	3.35e-100	298.0	COG1296@1|root,COG1296@2|Bacteria,1MVGN@1224|Proteobacteria,1S2AK@1236|Gammaproteobacteria,1XSZ2@135623|Vibrionales	135623|Vibrionales	E	branched-chain amino acid permease (azaleucine resistance)	-	-	-	-	-	-	-	-	-	-	-	-	AzlC
k141_1146_3	945550.VISI1226_04894	1.2e-37	129.0	COG4392@1|root,COG4392@2|Bacteria,1N6Z1@1224|Proteobacteria,1SCAB@1236|Gammaproteobacteria,1XYAS@135623|Vibrionales	135623|Vibrionales	S	branched-chain amino acid	-	-	-	-	-	-	-	-	-	-	-	-	AzlD
k141_1146_6	561231.Pecwa_0163	9.38e-24	95.1	2DQSI@1|root,338DY@2|Bacteria,1NKM5@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_520_1	1280944.HY17_03135	0.000438	46.6	COG1835@1|root,COG1835@2|Bacteria,1RI29@1224|Proteobacteria,2U9U3@28211|Alphaproteobacteria,43YC8@69657|Hyphomonadaceae	28211|Alphaproteobacteria	I	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
k141_520_2	1085623.GNIT_2556	9.95e-139	411.0	COG3307@1|root,COG3307@2|Bacteria,1PX0E@1224|Proteobacteria,1RYEB@1236|Gammaproteobacteria,468E7@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	O-Antigen ligase	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
k141_520_4	471854.Dfer_4019	4.99e-08	62.8	COG2244@1|root,COG2244@2|Bacteria,4NIZ6@976|Bacteroidetes,47TYF@768503|Cytophagia	976|Bacteroidetes	S	Polysaccharide biosynthesis protein	-	-	-	ko:K03328	-	-	-	-	ko00000	2.A.66.2	-	-	Polysacc_synt_3,Polysacc_synt_C
k141_1147_1	570952.ATVH01000015_gene1372	0.000314	49.7	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,2TQR7@28211|Alphaproteobacteria,2JPFH@204441|Rhodospirillales	204441|Rhodospirillales	NT	methyl-accepting chemotaxis protein	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,Hemerythrin,MCPsignal
k141_3164_1	96561.Dole_2808	4.08e-57	206.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42PZ5@68525|delta/epsilon subdivisions,2X72U@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	PFAM ATP-binding region, ATPase domain protein	-	-	2.7.13.3	ko:K07709	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
k141_2140_1	1232437.KL662001_gene4594	5.44e-26	107.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2WJ8D@28221|Deltaproteobacteria,2MICU@213118|Desulfobacterales	28221|Deltaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
k141_2140_2	679897.HMU07580	1e-31	129.0	COG0845@1|root,COG0845@2|Bacteria,1RI9S@1224|Proteobacteria,42T1D@68525|delta/epsilon subdivisions,2YPK5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
k141_2140_3	326423.RBAM_016680	1.54e-10	63.5	COG1846@1|root,COG1846@2|Bacteria,1V7H1@1239|Firmicutes,4HJ7F@91061|Bacilli,1ZG9S@1386|Bacillus	91061|Bacilli	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR
k141_2140_4	1121396.KB893051_gene3446	5.33e-208	586.0	COG1775@1|root,COG1775@2|Bacteria,1NNW9@1224|Proteobacteria,42PEQ@68525|delta/epsilon subdivisions,2WKWX@28221|Deltaproteobacteria,2MHQR@213118|Desulfobacterales	28221|Deltaproteobacteria	E	PFAM 2-hydroxyglutaryl-CoA dehydratase, D-component	-	-	-	-	-	-	-	-	-	-	-	-	HGD-D
k141_2140_5	879212.DespoDRAFT_03189	2.62e-23	95.1	COG1924@1|root,COG1924@2|Bacteria,1R6HU@1224|Proteobacteria,42PM0@68525|delta/epsilon subdivisions,2WJRP@28221|Deltaproteobacteria,2MHRM@213118|Desulfobacterales	28221|Deltaproteobacteria	I	PFAM BadF BadG BcrA BcrD ATPase family	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG
k141_3840_1	1441930.Z042_13715	2.59e-77	233.0	COG1762@1|root,COG1762@2|Bacteria,1RA06@1224|Proteobacteria,1S2SM@1236|Gammaproteobacteria,4053S@613|Serratia	1236|Gammaproteobacteria	G	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2	fruA_2	-	2.7.1.202	ko:K02768	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	M00273	R03232	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.2.1	-	-	PTS_EIIA_2
k141_3840_2	218493.SBG_1866	7.41e-55	172.0	COG1445@1|root,COG1445@2|Bacteria,1RHSU@1224|Proteobacteria,1S6R1@1236|Gammaproteobacteria,3ZMQ6@590|Salmonella	1236|Gammaproteobacteria	G	PTS system, Lactose/Cellobiose specific IIB subunit	frwB	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0008643,GO:0009401,GO:0015144,GO:0016020,GO:0016740,GO:0016772,GO:0016773,GO:0022804,GO:0022857,GO:0034219,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0090563,GO:0090582	2.7.1.202	ko:K02769,ko:K11202	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	M00273,M00306	R03232	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.2.1	-	-	PTS_IIB
k141_3840_3	1006000.GKAS_00445	3.55e-191	539.0	COG1299@1|root,COG1299@2|Bacteria,1R89F@1224|Proteobacteria,1RS14@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	and phosphoenolpyruvate-dependent sugar phosphotransferase system	-	-	-	ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	M00273	R03232	RC00017,RC03206	ko00000,ko00001,ko00002,ko02000	4.A.2.1	-	-	-
k141_3840_4	1147128.BAST_0023	6.66e-125	361.0	COG0036@1|root,COG0036@2|Bacteria,2IC1U@201174|Actinobacteria,4CZWV@85004|Bifidobacteriales	201174|Actinobacteria	G	Ribulose-phosphate 3 epimerase family	-	-	-	ko:K17195	ko00051,ko01120,map00051,map01120	-	R09031	RC03111	ko00000,ko00001,ko01000	-	-	-	Ribul_P_3_epim
k141_3840_6	1410620.SHLA_22c000250	5.06e-178	524.0	COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,2TQMR@28211|Alphaproteobacteria,4B6Z6@82115|Rhizobiaceae	28211|Alphaproteobacteria	V	ABC-type multidrug transport system, ATPase and permease	MA20_35245	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
k141_3840_7	391937.NA2_17419	3.51e-203	588.0	COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,2TQMR@28211|Alphaproteobacteria,43HDI@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	V	lipid A ABC exporter family, fused ATPase and inner membrane subunits	MA20_35245	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
k141_3840_9	945550.VISI1226_04405	2.97e-88	265.0	COG1309@1|root,COG1309@2|Bacteria,1N4KP@1224|Proteobacteria,1SACD@1236|Gammaproteobacteria,1XW2J@135623|Vibrionales	135623|Vibrionales	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
k141_3840_10	617140.AJZE01000091_gene4417	6.24e-180	505.0	COG0549@1|root,COG0549@2|Bacteria,1MWXC@1224|Proteobacteria,1RP78@1236|Gammaproteobacteria,1XVZA@135623|Vibrionales	135623|Vibrionales	E	Belongs to the carbamate kinase family	-	-	2.7.2.2	ko:K00926	ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200	-	R00150,R01395	RC00002,RC00043,RC02803,RC02804	ko00000,ko00001,ko01000	-	-	-	AA_kinase
k141_3840_11	617140.AJZE01000091_gene4418	1.09e-268	743.0	COG0531@1|root,COG0531@2|Bacteria,1MUP1@1224|Proteobacteria,1RR0V@1236|Gammaproteobacteria,1XVHJ@135623|Vibrionales	135623|Vibrionales	E	COG0531 Amino acid transporters	-	-	-	ko:K20265	ko02024,map02024	-	-	-	ko00000,ko00001,ko02000	2.A.3.7.1,2.A.3.7.3	-	-	AA_permease_2
k141_3840_12	1280001.BAOA01000007_gene3922	2.13e-236	653.0	COG2957@1|root,COG2957@2|Bacteria,1MX65@1224|Proteobacteria,1RMF1@1236|Gammaproteobacteria,1XVYW@135623|Vibrionales	135623|Vibrionales	E	agmatine deiminase	aguA	-	3.5.3.12	ko:K10536	ko00330,ko01100,map00330,map01100	-	R01416	RC00177	ko00000,ko00001,ko01000	-	-	-	PAD_porph
k141_3840_13	945550.VISI1226_04425	2.27e-226	626.0	COG0078@1|root,COG0078@2|Bacteria,1MUFM@1224|Proteobacteria,1RQ59@1236|Gammaproteobacteria,1XSKT@135623|Vibrionales	135623|Vibrionales	E	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain	-	-	2.1.3.6	ko:K13252	-	-	-	-	ko00000,ko01000	-	-	-	OTCace,OTCace_N
k141_3840_14	617140.AJZE01000059_gene2246	1.15e-200	561.0	COG0687@1|root,COG0687@2|Bacteria,1MUYW@1224|Proteobacteria,1RM7W@1236|Gammaproteobacteria,1XUH1@135623|Vibrionales	135623|Vibrionales	P	Required for the activity of the bacterial periplasmic transport system of putrescine	potD	-	-	ko:K11069	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	SBP_bac_6,SBP_bac_8
k141_3840_15	945543.VIBR0546_14812	1.13e-103	304.0	COG2095@1|root,COG2095@2|Bacteria,1RAFQ@1224|Proteobacteria,1S2XM@1236|Gammaproteobacteria,1XV46@135623|Vibrionales	135623|Vibrionales	U	COG2095 Multiple antibiotic transporter	-	-	-	ko:K05595	-	-	-	-	ko00000,ko02000	2.A.95.1	-	-	MarC
k141_3840_16	298386.PBPRB1917	1.13e-225	634.0	COG0531@1|root,COG0531@2|Bacteria,1MUP1@1224|Proteobacteria,1RR0V@1236|Gammaproteobacteria,1XVHJ@135623|Vibrionales	135623|Vibrionales	E	COG0531 Amino acid transporters	-	-	-	ko:K20265	ko02024,map02024	-	-	-	ko00000,ko00001,ko02000	2.A.3.7.1,2.A.3.7.3	-	-	AA_permease_2
k141_3840_17	675813.VIB_001164	5.36e-184	524.0	COG0477@1|root,COG2814@2|Bacteria,1QUI9@1224|Proteobacteria,1T32Z@1236|Gammaproteobacteria	1236|Gammaproteobacteria	EGP	Major facilitator superfamily	yceL	-	-	ko:K08162	-	-	-	-	ko00000,ko02000	2.A.1.2.21	-	-	MFS_1
k141_3840_18	29495.EA26_10800	1.53e-120	352.0	COG1120@1|root,COG1120@2|Bacteria,1MVKU@1224|Proteobacteria,1RN86@1236|Gammaproteobacteria,1XVHM@135623|Vibrionales	135623|Vibrionales	HP	ABC-type cobalamin Fe3 -siderophores transport systems, ATPase	-	-	3.6.3.34	ko:K02013	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	ABC_tran
k141_3840_20	29495.EA26_10790	4.01e-196	551.0	COG0614@1|root,COG0614@2|Bacteria,1MUSZ@1224|Proteobacteria,1RPUH@1236|Gammaproteobacteria,1XVTG@135623|Vibrionales	135623|Vibrionales	P	ABC-type Fe3 -hydroxamate transport system, periplasmic component	-	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
k141_2889_3	207559.Dde_3053	4.93e-237	660.0	COG2271@1|root,COG2271@2|Bacteria,1QTW2@1224|Proteobacteria,42U0W@68525|delta/epsilon subdivisions,2WQRX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
k141_2889_4	203275.BFO_0136	5.6e-136	395.0	COG1180@1|root,COG1180@2|Bacteria,4NIUZ@976|Bacteroidetes,2FP2R@200643|Bacteroidia,22XIT@171551|Porphyromonadaceae	976|Bacteroidetes	C	4Fe-4S single cluster domain	pflA	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4,Fer4_12,Radical_SAM
k141_2889_5	1121440.AUMA01000007_gene1117	6.16e-32	120.0	2DM2Z@1|root,31HGC@2|Bacteria,1N0CJ@1224|Proteobacteria,42TZ3@68525|delta/epsilon subdivisions,2WQCR@28221|Deltaproteobacteria,2MC33@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF4125)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4125
k141_2889_6	318167.Sfri_0429	1.04e-22	104.0	COG2203@1|root,COG5001@1|root,COG2203@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,2QAFJ@267890|Shewanellaceae	1236|Gammaproteobacteria	T	Diguanylate cyclase phosphodiesterase with GAF sensor	-	-	-	-	-	-	-	-	-	-	-	-	CHASE4,EAL,GAF_2,GGDEF
k141_4714_1	1499967.BAYZ01000194_gene3129	8.05e-94	285.0	COG4974@1|root,COG4974@2|Bacteria,2NRIN@2323|unclassified Bacteria	2|Bacteria	L	Phage integrase family	-	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_4,Phage_integrase
k141_3992_1	96561.Dole_2750	2.21e-56	177.0	COG4226@1|root,COG4226@2|Bacteria,1QW0X@1224|Proteobacteria,42UB8@68525|delta/epsilon subdivisions,2WQZG@28221|Deltaproteobacteria,2MNRM@213118|Desulfobacterales	28221|Deltaproteobacteria	S	PFAM HicB family protein	-	-	-	-	-	-	-	-	-	-	-	-	HicB
k141_4981_1	1283284.AZUK01000001_gene2101	2.34e-23	96.3	COG1397@1|root,COG1397@2|Bacteria,1NTUR@1224|Proteobacteria,1RMPE@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	ADP-ribosylation crystallin J1	draG	-	3.2.2.24	ko:K05521	-	-	-	-	ko00000,ko01000	-	-	-	ADP_ribosyl_GH
k141_4981_2	338963.Pcar_1580	6.52e-48	167.0	COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,42MFH@68525|delta/epsilon subdivisions,2WIRW@28221|Deltaproteobacteria,43TYZ@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	PFAM sigma-54 factor interaction domain-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,PAS_4,PAS_9,Sigma54_activat
k141_2890_1	1121396.KB893055_gene2620	1.77e-91	281.0	COG1488@1|root,COG1488@2|Bacteria,1MV8U@1224|Proteobacteria,42Q2U@68525|delta/epsilon subdivisions,2WM6I@28221|Deltaproteobacteria,2MJCS@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP	pncB	-	6.3.4.21	ko:K00763	ko00760,ko01100,map00760,map01100	-	R01724	RC00033	ko00000,ko00001,ko01000	-	-	-	NAPRTase
k141_2573_3	722419.PH505_aq00880	5.8e-191	564.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,2Q1SH@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF,GGDEF,PAS_9
k141_2573_4	1298865.H978DRAFT_0176	3.6e-62	212.0	COG3203@1|root,COG3203@2|Bacteria,1R91C@1224|Proteobacteria,1RTSN@1236|Gammaproteobacteria,467KV@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	Porin_4
k141_2573_5	1307437.J139_17580	3e-30	114.0	COG0226@1|root,COG0226@2|Bacteria,1N0P1@1224|Proteobacteria,1SBAQ@1236|Gammaproteobacteria,2Q30Z@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	P	Part of the ABC transporter complex PstSACB involved in phosphate import	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_2573_6	663278.Ethha_0858	5.22e-72	258.0	COG2203@1|root,COG5001@1|root,COG2203@2|Bacteria,COG5001@2|Bacteria,1TP8V@1239|Firmicutes,247PX@186801|Clostridia,3WJ1U@541000|Ruminococcaceae	186801|Clostridia	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF,GGDEF,HisKA_7TM
k141_2573_9	485918.Cpin_2187	1.32e-181	516.0	COG2273@1|root,COG2273@2|Bacteria,4NHP5@976|Bacteroidetes,1IY2Y@117747|Sphingobacteriia	976|Bacteroidetes	G	glycoside hydrolase family 16	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,Glyco_hydro_16
k141_2573_12	351348.Maqu_1073	7.29e-69	214.0	COG3809@1|root,COG3809@2|Bacteria,1RCM6@1224|Proteobacteria,1S22Z@1236|Gammaproteobacteria,46829@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Transcription factor zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-TFIIB
k141_4982_1	586413.CCDL010000004_gene3327	1.85e-72	240.0	COG0115@1|root,COG0147@1|root,COG0115@2|Bacteria,COG0147@2|Bacteria,1TQAP@1239|Firmicutes,4HBKC@91061|Bacilli,23J4J@182709|Oceanobacillus	91061|Bacilli	EH	Amino-transferase class IV	pabB	-	2.6.1.85,4.1.3.38	ko:K01665,ko:K03342,ko:K13950	ko00790,map00790	-	R01716,R05553	RC00010,RC01418,RC01843,RC02148	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_4,Chorismate_bind
k141_2007_2	1238450.VIBNISOn1_1180044	1.95e-48	155.0	COG1925@1|root,COG1925@2|Bacteria,1N0CV@1224|Proteobacteria,1S9R2@1236|Gammaproteobacteria,1XXVH@135623|Vibrionales	135623|Vibrionales	G	phosphocarrier protein hpr	ptsH	GO:0003674,GO:0003824,GO:0005215,GO:0006810,GO:0008150,GO:0008643,GO:0008982,GO:0009401,GO:0015144,GO:0016740,GO:0016772,GO:0016773,GO:0022804,GO:0022857,GO:0034219,GO:0051179,GO:0051234,GO:0055085,GO:0071702	-	ko:K02784	ko02060,map02060	-	-	-	ko00000,ko00001,ko02000	8.A.8.1.1	-	-	PTS-HPr
k141_2007_4	1517681.HW45_05610	8.68e-120	348.0	COG2981@1|root,COG2981@2|Bacteria,1MVFT@1224|Proteobacteria,1RMQT@1236|Gammaproteobacteria,1XTRY@135623|Vibrionales	135623|Vibrionales	U	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway	cysZ	GO:0003674,GO:0005215	-	ko:K06203	-	-	-	-	ko00000	-	-	-	EI24
k141_2007_5	945550.VISI1226_03285	1.25e-107	321.0	COG3115@1|root,COG3115@2|Bacteria,1MVHR@1224|Proteobacteria,1RMDB@1236|Gammaproteobacteria,1XSIV@135623|Vibrionales	135623|Vibrionales	D	Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins	zipA	-	-	ko:K03528	-	-	-	-	ko00000,ko03036	-	-	-	ZipA_C
k141_2007_6	945543.VIBR0546_09634	0.0	911.0	COG0272@1|root,COG0272@2|Bacteria,1MV3R@1224|Proteobacteria,1RPAV@1236|Gammaproteobacteria,1XSJC@135623|Vibrionales	135623|Vibrionales	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360,GO:1901576	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
k141_2320_1	1265505.ATUG01000001_gene2927	1e-219	628.0	COG1960@1|root,COG1960@2|Bacteria,1MU20@1224|Proteobacteria,42MUH@68525|delta/epsilon subdivisions,2WJ16@28221|Deltaproteobacteria,2MHYV@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Acyl-CoA dehydrogenase N terminal	-	-	-	ko:K09456	-	-	-	-	ko00000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_C,Acyl-CoA_dh_M,Acyl-CoA_dh_N,AcylCoA_DH_N
k141_2574_1	1321774.HMPREF9108_01321	1.64e-61	205.0	COG5379@1|root,COG5379@2|Bacteria,37BUE@32066|Fusobacteria	32066|Fusobacteria	I	Psort location Cytoplasmic, score 8.96	-	-	-	ko:K13622	ko00564,map00564	-	R09072	RC00021,RC01091	ko00000,ko00001	-	-	-	DUF3419
k141_4984_1	349741.Amuc_1314	7.36e-122	358.0	COG1533@1|root,COG1533@2|Bacteria,46S99@74201|Verrucomicrobia,2ITTT@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
k141_4984_2	998088.B565_0006	2.03e-12	65.9	COG2220@1|root,COG2220@2|Bacteria,1MVP2@1224|Proteobacteria,1RRSZ@1236|Gammaproteobacteria,1Y4E1@135624|Aeromonadales	135624|Aeromonadales	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2,Lactamase_B_3
k141_3993_1	1304885.AUEY01000090_gene2894	7.54e-130	374.0	COG1024@1|root,COG1024@2|Bacteria,1NSE1@1224|Proteobacteria,42PUH@68525|delta/epsilon subdivisions,2WMBE@28221|Deltaproteobacteria,2MMRQ@213118|Desulfobacterales	28221|Deltaproteobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
k141_3993_2	1304885.AUEY01000090_gene2895	9.43e-199	560.0	COG1979@1|root,COG1979@2|Bacteria,1QUBJ@1224|Proteobacteria,42MPI@68525|delta/epsilon subdivisions,2WJ2K@28221|Deltaproteobacteria,2MI8J@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Iron-containing alcohol dehydrogenase	-	-	-	ko:K08325	ko00640,map00640	-	R02528	RC00739	ko00000,ko00001,ko01000	-	-	-	Fe-ADH
k141_3993_3	1304885.AUEY01000090_gene2896	4.34e-28	107.0	COG1309@1|root,COG1309@2|Bacteria,1R6RX@1224|Proteobacteria,42T50@68525|delta/epsilon subdivisions,2WPVV@28221|Deltaproteobacteria,2MK9W@213118|Desulfobacterales	28221|Deltaproteobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	ko:K16137	-	-	-	-	ko00000,ko03000	-	-	-	TetR_C_13,TetR_N
k141_2892_1	161156.JQKW01000007_gene818	2.59e-36	137.0	COG1294@1|root,COG1294@2|Bacteria,2GH4P@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	C	Cytochrome bd terminal oxidase subunit II	-	-	1.10.3.14	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	Cyt_bd_oxida_II
k141_4715_1	999141.GME_05320	6.33e-177	501.0	COG1292@1|root,COG1292@2|Bacteria,1MV0K@1224|Proteobacteria,1RRSQ@1236|Gammaproteobacteria,1XIIN@135619|Oceanospirillales	1236|Gammaproteobacteria	M	Belongs to the BCCT transporter (TC 2.A.15) family	-	-	-	-	-	-	-	-	-	-	-	-	BCCT
k141_4715_2	1232437.KL662010_gene1576	2.27e-304	840.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,42M2A@68525|delta/epsilon subdivisions,2WIJY@28221|Deltaproteobacteria,2MHXB@213118|Desulfobacterales	28221|Deltaproteobacteria	S	ABC transporter	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_Xtn
k141_4715_3	743299.Acife_0378	0.000302	43.1	COG0697@1|root,COG0697@2|Bacteria,1MWSU@1224|Proteobacteria,1RSF8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	EG	Permeases of the drug metabolite transporter (DMT) superfamily	yyaM	-	-	-	-	-	-	-	-	-	-	-	EamA
k141_634_1	1262449.CP6013_2733	1.34e-97	291.0	COG4912@1|root,COG4912@2|Bacteria,1TQII@1239|Firmicutes,248N8@186801|Clostridia,36G61@31979|Clostridiaceae	186801|Clostridia	L	DNA alkylation repair	-	-	-	-	-	-	-	-	-	-	-	-	DNA_alkylation
k141_634_2	1007103.AFHW01000076_gene5650	6.09e-32	133.0	28JBJ@1|root,2Z968@2|Bacteria,1V29E@1239|Firmicutes,4HHQC@91061|Bacilli,26UTG@186822|Paenibacillaceae	91061|Bacilli	-	-	M1-1079	-	-	-	-	-	-	-	-	-	-	-	-
k141_634_3	65497.JODV01000025_gene1862	9.66e-26	117.0	COG1020@1|root,COG1020@2|Bacteria,2GWGZ@201174|Actinobacteria,4E0UY@85010|Pseudonocardiales	201174|Actinobacteria	Q	AMP-binding enzyme C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,PP-binding
k141_634_4	935837.JAEK01000005_gene4348	2.39e-103	313.0	COG0332@1|root,COG0332@2|Bacteria,1UYNP@1239|Firmicutes,4HECC@91061|Bacilli,1ZM97@1386|Bacillus	91061|Bacilli	I	Chalcone and stilbene synthases, N-terminal domain	fabH	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
k141_634_5	1123252.ATZF01000003_gene3450	3.17e-59	200.0	COG0451@1|root,COG0451@2|Bacteria,1TT3X@1239|Firmicutes,4HFYX@91061|Bacilli	91061|Bacilli	M	NAD dependent epimerase dehydratase family protein	galE1	-	-	-	-	-	-	-	-	-	-	-	3Beta_HSD,Epimerase
k141_634_6	1333507.AUTQ01000202_gene1057	1.79e-25	108.0	COG0491@1|root,COG0491@2|Bacteria,1QPNG@1224|Proteobacteria,1RSBT@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Metallo-Beta-Lactamase	gumP	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
k141_634_7	888833.HMPREF9421_1462	1.57e-94	298.0	COG1541@1|root,COG1541@2|Bacteria,1UYWT@1239|Firmicutes,4HD2R@91061|Bacilli	91061|Bacilli	H	Coenzyme F390 synthetase	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding
k141_634_9	929506.CbC4_2031	0.0	876.0	COG0488@1|root,COG0488@2|Bacteria,1TPW0@1239|Firmicutes,248ST@186801|Clostridia,36E0B@31979|Clostridiaceae	186801|Clostridia	S	ABC transporter	ykpA	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,ABC_tran_Xtn
k141_634_10	1123511.KB905839_gene528	2.59e-41	149.0	COG1295@1|root,COG1295@2|Bacteria,1U7HM@1239|Firmicutes,4H61C@909932|Negativicutes	909932|Negativicutes	S	Virulence factor BrkB	-	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
k141_634_11	1121324.CLIT_4c01060	2.99e-79	251.0	COG2855@1|root,COG2855@2|Bacteria,1TQYA@1239|Firmicutes,247X6@186801|Clostridia,25R1J@186804|Peptostreptococcaceae	186801|Clostridia	S	Conserved hypothetical protein 698	-	-	-	-	-	-	-	-	-	-	-	-	Cons_hypoth698
k141_634_12	526218.Sterm_1373	1.56e-121	364.0	COG1690@1|root,COG1690@2|Bacteria,379MD@32066|Fusobacteria	32066|Fusobacteria	S	tRNA-splicing ligase RtcB	-	-	-	-	-	-	-	-	-	-	-	-	RtcB
k141_634_13	1033737.CAEV01000089_gene214	2.21e-123	371.0	COG1686@1|root,COG1686@2|Bacteria,1V37K@1239|Firmicutes,247XD@186801|Clostridia,36DEX@31979|Clostridiaceae	186801|Clostridia	M	Belongs to the peptidase S11 family	-	-	3.4.16.4	ko:K01286	-	-	-	-	ko00000,ko01000	-	-	-	Peptidase_S11
k141_634_14	1540257.JQMW01000009_gene3016	2.54e-169	489.0	COG0531@1|root,COG0531@2|Bacteria,1TQ4K@1239|Firmicutes,25E7A@186801|Clostridia,36E67@31979|Clostridiaceae	186801|Clostridia	E	amino acid	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2,Usp
k141_634_15	1540257.JQMW01000009_gene3014	3.6e-214	622.0	COG3829@1|root,COG3829@2|Bacteria,1TP0E@1239|Firmicutes,247MB@186801|Clostridia,36DY7@31979|Clostridiaceae	186801|Clostridia	KT	PFAM sigma-54 factor interaction domain-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_12,HTH_8,PAS,PAS_8,Sigma54_activat
k141_634_16	1321778.HMPREF1982_03163	6.07e-132	410.0	COG1506@1|root,COG1506@2|Bacteria,1TR2N@1239|Firmicutes,249FQ@186801|Clostridia,26AER@186813|unclassified Clostridiales	186801|Clostridia	E	Prolyl oligopeptidase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S9
k141_634_17	1033737.CAEV01000043_gene1438	2e-131	386.0	COG0624@1|root,COG0624@2|Bacteria,1TT3H@1239|Firmicutes,25CA7@186801|Clostridia,36WS5@31979|Clostridiaceae	186801|Clostridia	E	Peptidase dimerisation domain	-	-	3.5.1.18	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R02734	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20
k141_4986_1	1415755.JQLV01000001_gene1316	7.71e-76	252.0	COG3083@1|root,COG3083@2|Bacteria,1MX6X@1224|Proteobacteria,1RPAU@1236|Gammaproteobacteria,1XIUH@135619|Oceanospirillales	135619|Oceanospirillales	S	hydrolase of alkaline phosphatase superfamily	-	-	-	ko:K07014	-	-	-	-	ko00000	-	-	-	DUF3413,Sulfatase
k141_4716_1	1304872.JAGC01000003_gene3289	2.11e-93	280.0	COG0745@1|root,COG0745@2|Bacteria,1MU67@1224|Proteobacteria,42N90@68525|delta/epsilon subdivisions,2WJUU@28221|Deltaproteobacteria,2MA2P@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	response regulator, receiver	-	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
k141_4716_2	326442.PSHAa2774	7.93e-17	82.0	COG1368@1|root,COG1368@2|Bacteria,1MVCM@1224|Proteobacteria,1RNJ3@1236|Gammaproteobacteria,2Q0V1@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	M	Sulfatase	-	-	2.7.8.20	ko:K01002	ko01100,map01100	-	-	-	ko00000,ko01000	-	-	-	Sulfatase
k141_3694_2	1348635.BBJY01000007_gene143	9.92e-170	482.0	COG3500@1|root,COG3500@2|Bacteria,1MXT8@1224|Proteobacteria,1RMKC@1236|Gammaproteobacteria,1XZ6C@135623|Vibrionales	135623|Vibrionales	S	Phage late control gene D protein (GPD)	-	-	-	-	-	-	-	-	-	-	-	-	Phage_GPD
k141_3694_3	1348635.BBJY01000007_gene144	1.35e-36	124.0	2AXMF@1|root,31PMQ@2|Bacteria,1QMB3@1224|Proteobacteria,1TJJK@1236|Gammaproteobacteria,1Y1BM@135623|Vibrionales	135623|Vibrionales	S	Phage Tail Protein X	-	-	-	-	-	-	-	-	-	-	-	-	Phage_tail_X
k141_3694_4	1348635.BBJY01000007_gene145	1.18e-77	232.0	COG3499@1|root,COG3499@2|Bacteria,1QT2C@1224|Proteobacteria,1TAM4@1236|Gammaproteobacteria,1XZ1J@135623|Vibrionales	135623|Vibrionales	S	Phage P2 GpU	-	-	-	-	-	-	-	-	-	-	-	-	Phage_P2_GpU
k141_3694_5	1348635.BBJY01000007_gene146	0.0	987.0	COG5283@1|root,COG5283@2|Bacteria,1R5KW@1224|Proteobacteria,1T295@1236|Gammaproteobacteria,1Y3BA@135623|Vibrionales	135623|Vibrionales	S	phage tail tape measure protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_3694_7	1348635.BBJY01000007_gene148	7.66e-84	251.0	COG3498@1|root,COG3498@2|Bacteria,1QM3K@1224|Proteobacteria,1TJB3@1236|Gammaproteobacteria,1Y0XV@135623|Vibrionales	135623|Vibrionales	S	Phage tail tube protein FII	-	-	-	-	-	-	-	-	-	-	-	-	Phage_tube
k141_3694_8	1348635.BBJY01000007_gene149	2.9e-255	702.0	COG3497@1|root,COG3497@2|Bacteria,1MW1V@1224|Proteobacteria,1RNUT@1236|Gammaproteobacteria,1XY5S@135623|Vibrionales	135623|Vibrionales	S	Phage tail sheath protein subtilisin-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Phage_sheath_1,Phage_sheath_1C
k141_2021_1	1191299.AJYX01000097_gene1822	5.9e-254	706.0	COG2610@1|root,COG2610@2|Bacteria,1MUFG@1224|Proteobacteria,1RNGE@1236|Gammaproteobacteria,1XVND@135623|Vibrionales	135623|Vibrionales	EG	COG2610 H gluconate symporter and related permeases	-	-	-	ko:K03299	-	-	-	-	ko00000,ko02000	2.A.8	-	-	GntP_permease
k141_2021_2	1280001.BAOA01000007_gene3965	3.25e-135	388.0	COG3622@1|root,COG3622@2|Bacteria,1MV53@1224|Proteobacteria,1RQF9@1236|Gammaproteobacteria,1XTG3@135623|Vibrionales	135623|Vibrionales	G	Belongs to the hyi family	-	-	5.3.1.35	ko:K22131	-	-	-	-	ko00000,ko01000	-	-	-	AP_endonuc_2
k141_2021_3	1191299.AJYX01000097_gene1820	3.29e-38	133.0	COG0235@1|root,COG0235@2|Bacteria,1MW7B@1224|Proteobacteria,1RS8X@1236|Gammaproteobacteria,1XVYB@135623|Vibrionales	135623|Vibrionales	G	Class II Aldolase and Adducin N-terminal domain	-	-	4.1.1.104	ko:K22130	-	-	-	-	ko00000,ko01000	-	-	-	Aldolase_II
k141_4312_1	1304885.AUEY01000026_gene3573	1.84e-18	77.8	COG2768@1|root,COG2768@2|Bacteria,1R09F@1224|Proteobacteria,43CSG@68525|delta/epsilon subdivisions,2X803@28221|Deltaproteobacteria,2MPMR@213118|Desulfobacterales	28221|Deltaproteobacteria	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4
k141_4312_3	1304885.AUEY01000026_gene3564	1.99e-169	491.0	COG0595@1|root,COG0595@2|Bacteria,1MUGV@1224|Proteobacteria,42M65@68525|delta/epsilon subdivisions,2WIQ9@28221|Deltaproteobacteria,2MHNU@213118|Desulfobacterales	28221|Deltaproteobacteria	S	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay	rnj	-	-	ko:K12574	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	Lactamase_B,Lactamase_B_2,RMMBL
k141_2913_1	553219.CAMSH0001_1224	1.23e-58	195.0	COG3315@1|root,COG3315@2|Bacteria,1RAX6@1224|Proteobacteria,42SC3@68525|delta/epsilon subdivisions,2YPPV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	Q	Leucine carboxyl methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	LCM
k141_2913_2	1242864.D187_000791	1.62e-47	175.0	COG0477@1|root,COG2814@2|Bacteria,1MUZ8@1224|Proteobacteria,43BBM@68525|delta/epsilon subdivisions	1224|Proteobacteria	EGP	Major Facilitator Superfamily	ybtX	-	-	ko:K05373,ko:K08218	ko01501,map01501	M00628	-	-	ko00000,ko00001,ko00002,ko02000	2.A.1,2.A.1.25	-	-	Acatn,MFS_1
k141_2913_3	177437.HRM2_41620	1.41e-154	449.0	COG0477@1|root,COG2814@2|Bacteria,1R590@1224|Proteobacteria,42P8I@68525|delta/epsilon subdivisions,2WKQ6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
k141_2913_4	298386.PBPRA1244	2.51e-28	112.0	COG1051@1|root,COG1763@1|root,COG1051@2|Bacteria,COG1763@2|Bacteria,1RD3Q@1224|Proteobacteria,1S72P@1236|Gammaproteobacteria,1XWZJ@135623|Vibrionales	135623|Vibrionales	H	Molybdopterin guanine dinucleotide synthesis protein B	-	-	-	ko:K03753	-	-	-	-	ko00000	-	-	-	MobB
k141_4010_1	177437.HRM2_05340	3.07e-158	475.0	COG1198@1|root,COG1198@2|Bacteria,1MUUZ@1224|Proteobacteria,42MNH@68525|delta/epsilon subdivisions,2WJ4G@28221|Deltaproteobacteria,2MINK@213118|Desulfobacterales	28221|Deltaproteobacteria	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,ResIII
k141_4010_3	913848.AELK01000182_gene913	9.54e-07	52.8	COG1198@1|root,COG1198@2|Bacteria,1TNYB@1239|Firmicutes,4H9WW@91061|Bacilli,3F3N8@33958|Lactobacillaceae	91061|Bacilli	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,ResIII
k141_4010_4	941639.BCO26_2713	3.19e-155	458.0	COG3039@1|root,COG3039@2|Bacteria,1TRUS@1239|Firmicutes,4HCCQ@91061|Bacilli,1ZHBM@1386|Bacillus	91061|Bacilli	L	Transposase, IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_2,DUF772
k141_3733_1	1121405.dsmv_1440	2.3e-44	164.0	COG0557@1|root,COG0557@2|Bacteria,1MUS6@1224|Proteobacteria,42NHP@68525|delta/epsilon subdivisions,2X6U1@28221|Deltaproteobacteria,2MHMI@213118|Desulfobacterales	28221|Deltaproteobacteria	K	PFAM ribonuclease II	-	-	3.1.13.1	ko:K01147,ko:K12573	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	OB_RNB,RNB,S1
k141_3733_2	1121396.KB893069_gene1404	6.76e-65	218.0	COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,42NCR@68525|delta/epsilon subdivisions,2WKMY@28221|Deltaproteobacteria,2MHTZ@213118|Desulfobacterales	28221|Deltaproteobacteria	V	ABC transporter transmembrane region	-	-	-	ko:K06147,ko:K18889	ko02010,map02010	M00707	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.106,3.A.1.106.13,3.A.1.106.5,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
k141_2349_1	1283284.AZUK01000001_gene161	6.4e-132	379.0	COG0834@1|root,COG0834@2|Bacteria,1NT2J@1224|Proteobacteria,1RRYR@1236|Gammaproteobacteria,1Y6D1@135624|Aeromonadales	135624|Aeromonadales	ET	Bacterial periplasmic substrate-binding proteins	-	-	-	ko:K10014	ko02010,map02010	M00226	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3.1	-	-	SBP_bac_3
k141_2349_2	1301098.PKB_1463	7.63e-32	119.0	COG4215@1|root,COG4215@2|Bacteria,1MY2N@1224|Proteobacteria,1RNYD@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	(ABC) transporter	aotQ	-	-	ko:K10016,ko:K10024	ko02010,map02010	M00225,M00226,M00235	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3.1,3.A.1.3.11	-	-	BPD_transp_1
k141_2349_3	595494.Tola_1580	5.57e-32	117.0	COG4215@1|root,COG4215@2|Bacteria,1MY2N@1224|Proteobacteria,1RNYD@1236|Gammaproteobacteria,1Y47J@135624|Aeromonadales	135624|Aeromonadales	P	ABC transporter	-	-	-	ko:K10016	ko02010,map02010	M00225,M00226	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3.1	-	-	BPD_transp_1
k141_2349_4	1283284.AZUK01000001_gene159	8.94e-92	274.0	COG4160@1|root,COG4160@2|Bacteria,1MWI6@1224|Proteobacteria,1RPT1@1236|Gammaproteobacteria,1Y46G@135624|Aeromonadales	1236|Gammaproteobacteria	P	Binding-protein-dependent transport system inner membrane component	hisM	GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0015711,GO:0015849,GO:0016020,GO:0044464,GO:0046942,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944	-	ko:K10015	ko02010,map02010	M00225,M00226	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3.1	-	iAF1260.b2307,iAPECO1_1312.APECO1_4257,iB21_1397.B21_02192,iBWG_1329.BWG_2081,iE2348C_1286.E2348C_2447,iEC55989_1330.EC55989_2551,iECABU_c1320.ECABU_c26390,iECBD_1354.ECBD_1352,iECB_1328.ECB_02232,iECDH10B_1368.ECDH10B_2469,iECDH1ME8569_1439.ECDH1ME8569_2245,iECD_1391.ECD_02232,iECED1_1282.ECED1_2771,iECH74115_1262.ECH74115_3447,iECIAI1_1343.ECIAI1_2383,iECIAI39_1322.ECIAI39_2456,iECNA114_1301.ECNA114_2397,iECO103_1326.ECO103_2771,iECO111_1330.ECO111_3055,iECO26_1355.ECO26_3295,iECOK1_1307.ECOK1_2540,iECP_1309.ECP_2346,iECS88_1305.ECS88_2454,iECSE_1348.ECSE_2616,iECSF_1327.ECSF_2183,iECSP_1301.ECSP_3182,iECW_1372.ECW_m2496,iECs_1301.ECs3191,iEKO11_1354.EKO11_1458,iETEC_1333.ETEC_2443,iEcDH1_1363.EcDH1_1349,iEcE24377_1341.EcE24377A_2601,iEcSMS35_1347.EcSMS35_2463,iEcolC_1368.EcolC_1345,iG2583_1286.G2583_2844,iJO1366.b2307,iJR904.b2307,iLF82_1304.LF82_1007,iNRG857_1313.NRG857_11685,iSDY_1059.SDY_2506,iSFV_1184.SFV_2374,iSF_1195.SF2383,iSFxv_1172.SFxv_2628,iSSON_1240.SSON_2365,iS_1188.S2518,iSbBS512_1146.SbBS512_E2685,iUMN146_1321.UM146_05275,iUMNK88_1353.UMNK88_2858,iUTI89_1310.UTI89_C2591,iWFL_1372.ECW_m2496,iY75_1357.Y75_RS12100,ic_1306.c2849	BPD_transp_1
k141_2349_5	1443113.LC20_03719	3.61e-135	389.0	COG4598@1|root,COG4598@2|Bacteria,1QTS2@1224|Proteobacteria,1RQYN@1236|Gammaproteobacteria,41EU5@629|Yersinia	1236|Gammaproteobacteria	E	Histidine ABC transporter ATP-binding protein	hisP	-	3.6.3.21	ko:K10017	ko02010,map02010	M00225,M00226	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.3.1	-	iECIAI39_1322.ECIAI39_2455,iPC815.YPO2777,iYL1228.KPN_02696,iZ_1308.Z3568	ABC_tran
k141_4011_1	398512.JQKC01000046_gene5653	1.11e-29	113.0	2EEWP@1|root,338Q1@2|Bacteria,1VWSS@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_4314_1	1265505.ATUG01000002_gene1795	1.41e-35	132.0	COG3434@1|root,COG3434@2|Bacteria,1MVW1@1224|Proteobacteria,42MIH@68525|delta/epsilon subdivisions,2WK3V@28221|Deltaproteobacteria,2MIQC@213118|Desulfobacterales	28221|Deltaproteobacteria	T	PFAM EAL domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,HDOD
k141_2599_2	1280001.BAOA01000047_gene1723	1.89e-142	406.0	COG0327@1|root,COG0327@2|Bacteria,1MVUN@1224|Proteobacteria,1RNBU@1236|Gammaproteobacteria,1XUIZ@135623|Vibrionales	135623|Vibrionales	S	NIF3 (NGG1p interacting factor 3)	ybgI	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	-	-	-	-	-	-	-	-	-	NIF3
k141_2599_3	675815.VOA_002438	6e-39	138.0	COG3782@1|root,COG3782@2|Bacteria,1N971@1224|Proteobacteria,1SD24@1236|Gammaproteobacteria,1XSBE@135623|Vibrionales	135623|Vibrionales	S	protein conserved in bacteria	-	-	-	ko:K09977	-	-	-	-	ko00000	-	-	-	DUF1853
k141_2351_1	479432.Sros_8267	1.68e-10	64.3	COG1309@1|root,COG1309@2|Bacteria,2IN8A@201174|Actinobacteria,4EJTA@85012|Streptosporangiales	201174|Actinobacteria	K	AefR-like transcriptional repressor, C-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_7,TetR_N
k141_2916_1	1304888.ATWF01000002_gene338	2.43e-21	97.1	COG3103@1|root,COG3103@2|Bacteria	2|Bacteria	T	Sh3 type 3 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF1302
k141_4471_6	189425.PGRAT_01790	3.65e-57	193.0	COG0444@1|root,COG0444@2|Bacteria,1TP6E@1239|Firmicutes,4HC95@91061|Bacilli,26UIV@186822|Paenibacillaceae	91061|Bacilli	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K02031	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
k141_4471_7	545694.TREPR_0828	2.05e-48	170.0	COG4608@1|root,COG4608@2|Bacteria,2J9TC@203691|Spirochaetes	203691|Spirochaetes	P	Belongs to the ABC transporter superfamily	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,oligo_HPY
k141_4471_8	1123373.ATXI01000029_gene765	3.2e-44	157.0	COG2875@1|root,COG2875@2|Bacteria,2GH95@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	H	Tetrapyrrole (Corrin/Porphyrin) Methylases	-	-	-	-	-	-	-	-	-	-	-	-	TP_methylase
k141_4471_9	1249627.D779_2881	4.7e-49	172.0	COG0583@1|root,COG0583@2|Bacteria,1R4JK@1224|Proteobacteria,1RYBH@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	transcriptional regulator	irgB	GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031326,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1903506,GO:2000112,GO:2001141	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
k141_4471_10	223283.PSPTO_3044	8.45e-14	70.5	COG2801@1|root,COG2801@2|Bacteria,1MVXQ@1224|Proteobacteria,1RPEW@1236|Gammaproteobacteria,1Z6HT@136849|Pseudomonas syringae group	1236|Gammaproteobacteria	L	transposase OrfB	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve
k141_105_1	438753.AZC_4408	1.84e-32	121.0	COG1126@1|root,COG1126@2|Bacteria,1MU9Q@1224|Proteobacteria,2TQX2@28211|Alphaproteobacteria,3F0K7@335928|Xanthobacteraceae	28211|Alphaproteobacteria	E	ATPases associated with a variety of cellular activities	glnQ	-	3.6.3.21	ko:K02028,ko:K09972,ko:K10004	ko02010,ko02020,map02010,map02020	M00230,M00232,M00236	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.3,3.A.1.3.17,3.A.1.3.18,3.A.1.3.19,3.A.1.3.4,3.A.1.3.7,3.A.1.3.8	-	-	ABC_tran
k141_105_2	309807.SRU_2421	5.23e-85	267.0	COG0003@1|root,COG0003@2|Bacteria,4PAFA@976|Bacteroidetes,1FJT1@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	P	Anion-transporting ATPase	-	-	3.6.3.16	ko:K01551	-	-	-	-	ko00000,ko01000,ko02000	3.A.19.1,3.A.21.1,3.A.4.1	-	-	ArsA_ATPase
k141_418_1	324057.Pjdr2_1410	1.17e-110	375.0	COG0747@1|root,COG1361@1|root,COG3210@1|root,COG4733@1|root,COG5184@1|root,COG5492@1|root,COG0747@2|Bacteria,COG1361@2|Bacteria,COG3210@2|Bacteria,COG4733@2|Bacteria,COG5184@2|Bacteria,COG5492@2|Bacteria,1VX9E@1239|Firmicutes,4HIIK@91061|Bacilli,26SBE@186822|Paenibacillaceae	91061|Bacilli	M	S-layer homology domain	-	-	-	-	-	-	-	-	-	-	-	-	Big_3_5,MucBP,SLH
k141_3488_1	1220582.RRU01S_18_00460	9.14e-72	234.0	COG1408@1|root,COG1408@2|Bacteria,1MUH5@1224|Proteobacteria,2TVHN@28211|Alphaproteobacteria,4BA6U@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Calcineurin-like phosphoesterase	-	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	Metallophos
k141_3488_2	1266845.Q783_05265	4.88e-07	50.4	COG0667@1|root,COG0667@2|Bacteria,1TPIY@1239|Firmicutes,4HA4Q@91061|Bacilli,27HI6@186828|Carnobacteriaceae	91061|Bacilli	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
k141_419_1	443254.Marpi_0276	8.23e-57	197.0	COG1203@1|root,COG1203@2|Bacteria,2GDCY@200918|Thermotogae	200918|Thermotogae	L	TIGRFAM CRISPR-associated helicase Cas3	-	-	-	ko:K07012	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	DEAD,HD,Helicase_C
k141_3489_1	1089550.ATTH01000002_gene104	1.29e-34	137.0	COG3290@1|root,COG5002@1|root,COG3290@2|Bacteria,COG5002@2|Bacteria,4PKV1@976|Bacteroidetes,1FJW3@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	T	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
k141_420_1	290512.Paes_1391	2.03e-08	56.2	COG0463@1|root,COG0463@2|Bacteria,1FEB3@1090|Chlorobi	1090|Chlorobi	M	PFAM glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
k141_420_2	373903.Hore_22850	5.81e-12	69.3	COG2244@1|root,COG2244@2|Bacteria,1VAKC@1239|Firmicutes,24PMX@186801|Clostridia	186801|Clostridia	S	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_C
k141_106_1	318161.Sden_0634	6.49e-27	111.0	COG2977@1|root,COG2977@2|Bacteria,1MZK2@1224|Proteobacteria,1S968@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	Belongs to the P-Pant transferase superfamily	ngrA	-	6.3.2.14	ko:K02362	ko01053,ko01110,ko01130,map01053,map01110,map01130	-	R07644	RC00162,RC03046	ko00000,ko00001,ko01000	-	-	-	ACPS
k141_3490_1	1304885.AUEY01000013_gene3111	2.86e-81	248.0	COG0854@1|root,COG0854@2|Bacteria,1MU9W@1224|Proteobacteria,42NZY@68525|delta/epsilon subdivisions,2WJDY@28221|Deltaproteobacteria,2MJ54@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate	pdxJ	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	2.6.99.2	ko:K03474	ko00750,ko01100,map00750,map01100	M00124	R05838	RC01476	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1885	PdxJ
k141_107_1	1002339.HMPREF9373_1614	1.06e-33	124.0	COG1028@1|root,COG1028@2|Bacteria,1MWGC@1224|Proteobacteria,1RRE1@1236|Gammaproteobacteria,3NM4Z@468|Moraxellaceae	1236|Gammaproteobacteria	IQ	KR domain	HA62_15005	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
k141_107_2	1196031.ALEG01000065_gene92	2.63e-11	65.5	COG1250@1|root,COG1250@2|Bacteria,1TPA4@1239|Firmicutes,4HEAF@91061|Bacilli,1ZC1S@1386|Bacillus	91061|Bacilli	I	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain	-	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
k141_3491_1	1265505.ATUG01000001_gene4114	2.17e-44	154.0	COG0500@1|root,COG2226@2|Bacteria,1R6ZI@1224|Proteobacteria,42R1Q@68525|delta/epsilon subdivisions,2WN15@28221|Deltaproteobacteria,2MJKD@213118|Desulfobacterales	28221|Deltaproteobacteria	Q	Mycolic acid cyclopropane synthetase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
k141_3777_4	1304284.L21TH_0825	4.98e-253	711.0	COG1292@1|root,COG1292@2|Bacteria,1TRS6@1239|Firmicutes,2482K@186801|Clostridia,36E19@31979|Clostridiaceae	186801|Clostridia	M	Belongs to the BCCT transporter (TC 2.A.15) family	-	-	-	ko:K02168,ko:K03451,ko:K05020	-	-	-	-	ko00000,ko02000	2.A.15,2.A.15.1.1,2.A.15.1.11,2.A.15.1.3,2.A.15.1.4	-	-	BCCT
k141_3777_5	411465.PEPMIC_00958	7.19e-22	97.1	COG1309@1|root,COG1309@2|Bacteria,1V7BK@1239|Firmicutes,24HI0@186801|Clostridia,22HZE@1570339|Peptoniphilaceae	186801|Clostridia	K	Bacterial regulatory proteins, tetR family	grdR	-	-	-	-	-	-	-	-	-	-	-	TetR_N
k141_3777_7	572544.Ilyop_1733	2.01e-154	446.0	COG0517@1|root,COG1125@1|root,COG0517@2|Bacteria,COG1125@2|Bacteria,378UF@32066|Fusobacteria	32066|Fusobacteria	E	ABC transporter	-	-	-	ko:K05847	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	ABC_tran,CBS
k141_3777_8	37659.JNLN01000001_gene1899	2.85e-145	434.0	COG1174@1|root,COG1732@1|root,COG1174@2|Bacteria,COG1732@2|Bacteria,1TQ7D@1239|Firmicutes,248A1@186801|Clostridia,36DBY@31979|Clostridiaceae	186801|Clostridia	P	glycine, betaine	opuCC	-	-	ko:K05845,ko:K05846	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	BPD_transp_1,OpuAC
k141_3777_9	1540257.JQMW01000011_gene2546	7.28e-61	197.0	COG1309@1|root,COG1309@2|Bacteria,1V7BK@1239|Firmicutes,24HI0@186801|Clostridia,36I31@31979|Clostridiaceae	186801|Clostridia	K	Bacterial regulatory proteins, tetR family	grdR	-	-	-	-	-	-	-	-	-	-	-	TetR_N
k141_3777_10	536227.CcarbDRAFT_5424	3.34e-275	758.0	28HF7@1|root,2Z7RC@2|Bacteria,1TQET@1239|Firmicutes,249YW@186801|Clostridia,36FG0@31979|Clostridiaceae	186801|Clostridia	C	PFAM Glycine sarcosine betaine reductase complex, protein B, alpha and beta subunits	grdI	-	1.21.4.4	ko:K21578	-	-	-	-	ko00000,ko01000	-	-	-	Gly_reductase
k141_3777_11	748727.CLJU_c27350	7.69e-199	560.0	COG1978@1|root,COG1978@2|Bacteria,1TPAB@1239|Firmicutes,2487X@186801|Clostridia,36DEZ@31979|Clostridiaceae	186801|Clostridia	S	glycine betaine sarcosine D-proline reductase family	grdH	-	1.21.4.4	ko:K21579	-	-	-	-	ko00000,ko01000	-	-	-	GRDB
k141_3777_12	1540257.JQMW01000011_gene2549	1.68e-44	144.0	2DMJK@1|root,32RZN@2|Bacteria,1VBA0@1239|Firmicutes,24MQW@186801|Clostridia,36KIM@31979|Clostridiaceae	186801|Clostridia	S	glycine reductase, selenoprotein B	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_3777_13	1151292.QEW_2891	8.48e-50	160.0	COG3118@1|root,COG3118@2|Bacteria,1UHX3@1239|Firmicutes,24JPM@186801|Clostridia,25RVE@186804|Peptostreptococcaceae	186801|Clostridia	O	Belongs to the thioredoxin family	trxA	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
k141_3777_14	1408422.JHYF01000015_gene471	1.19e-18	77.0	2DR3E@1|root,33A02@2|Bacteria,1VKEX@1239|Firmicutes,24UH8@186801|Clostridia,36P60@31979|Clostridiaceae	186801|Clostridia	S	Glycine reductase complex selenoprotein A	grdA	-	1.21.4.2,1.21.4.3,1.21.4.4	ko:K10670	-	-	-	-	ko00000,ko01000	-	-	-	GRDA
k141_3777_15	742765.HMPREF9457_03824	4.33e-56	176.0	2AE14@1|root,313TT@2|Bacteria,1V6GX@1239|Firmicutes,24K4C@186801|Clostridia,27VQP@189330|Dorea	186801|Clostridia	C	COG NOG11771 non supervised orthologous group	grdA	-	1.21.4.2,1.21.4.3,1.21.4.4	ko:K10670	-	-	-	-	ko00000,ko01000	-	-	-	GRDA
k141_3493_1	290317.Cpha266_1371	1.09e-23	99.0	COG0420@1|root,COG0420@2|Bacteria,1FDTG@1090|Chlorobi	1090|Chlorobi	L	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity	sbcD	-	-	ko:K03547	-	-	-	-	ko00000,ko03400	-	-	-	Metallophos,SbcD_C
k141_2072_1	1348635.BBJY01000001_gene2336	9.1e-107	312.0	COG0518@1|root,COG0518@2|Bacteria,1MUDH@1224|Proteobacteria,1RXUZ@1236|Gammaproteobacteria,1XW7Y@135623|Vibrionales	135623|Vibrionales	F	Glutamine amidotransferase class-I	-	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase
k141_2072_2	693444.D782_1044	6.38e-41	140.0	COG1051@1|root,COG1051@2|Bacteria,1QU7E@1224|Proteobacteria,1T1PU@1236|Gammaproteobacteria	1236|Gammaproteobacteria	F	NUDIX hydrolase	-	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
k141_2072_3	1192124.LIG30_4952	9.4e-44	159.0	COG0583@1|root,COG0583@2|Bacteria,1PI4F@1224|Proteobacteria,2W6Q9@28216|Betaproteobacteria,1K52G@119060|Burkholderiaceae	28216|Betaproteobacteria	K	transcriptional Regulator, LysR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
k141_2072_4	342610.Patl_0874	3.08e-213	607.0	COG2272@1|root,COG2272@2|Bacteria,1MVQZ@1224|Proteobacteria,1RPFW@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	Belongs to the type-B carboxylesterase lipase family	estA1	-	-	ko:K03929	-	-	-	-	ko00000,ko01000	-	CE10	-	COesterase
k141_2072_5	1517681.HW45_09750	1.21e-58	185.0	COG1869@1|root,COG1869@2|Bacteria,1RI53@1224|Proteobacteria,1S60T@1236|Gammaproteobacteria,1XX9V@135623|Vibrionales	135623|Vibrionales	G	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose	rbsD	GO:0003674,GO:0003824,GO:0005215,GO:0006810,GO:0008150,GO:0008643,GO:0015144,GO:0015145,GO:0015146,GO:0015399,GO:0015405,GO:0015407,GO:0015591,GO:0015608,GO:0015611,GO:0015749,GO:0015750,GO:0015752,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0034219,GO:0042623,GO:0042626,GO:0043211,GO:0043492,GO:0051119,GO:0051179,GO:0051234,GO:0055085,GO:0071702	5.4.99.62	ko:K06726	ko02010,map02010	-	R08247	RC02247	ko00000,ko00001,ko01000	-	-	-	RbsD_FucU
k141_108_1	1265505.ATUG01000002_gene1753	7.95e-23	111.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42N1S@68525|delta/epsilon subdivisions,2WK7R@28221|Deltaproteobacteria,2MMS2@213118|Desulfobacterales	28221|Deltaproteobacteria	NT	PFAM histidine kinase HAMP region domain protein	mcp40H-21	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,CHASE3,HAMP,MCPsignal,dCache_1
k141_2073_1	318161.Sden_2352	2.84e-10	63.5	COG1074@1|root,COG1074@2|Bacteria,1MUTF@1224|Proteobacteria,1RPC6@1236|Gammaproteobacteria,2Q8K4@267890|Shewanellaceae	1236|Gammaproteobacteria	L	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA	recB	GO:0000166,GO:0000724,GO:0000725,GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0004518,GO:0004519,GO:0004520,GO:0004527,GO:0004529,GO:0004536,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006952,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0008854,GO:0009314,GO:0009338,GO:0009628,GO:0009987,GO:0015616,GO:0016043,GO:0016462,GO:0016787,GO:0016788,GO:0016796,GO:0016817,GO:0016818,GO:0016887,GO:0016895,GO:0017076,GO:0017111,GO:0030554,GO:0032392,GO:0032508,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034641,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044355,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0097159,GO:0097367,GO:0099046,GO:0140097,GO:1901265,GO:1901360,GO:1901363,GO:1902494	3.1.11.5	ko:K03582	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
k141_3780_1	1229172.JQFA01000004_gene1187	1.9e-40	147.0	COG1473@1|root,COG1473@2|Bacteria,1G01G@1117|Cyanobacteria,1H8F4@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM Peptidase family M20 M25 M40	ama	-	-	ko:K01436	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
k141_421_1	491952.Mar181_0086	0.0	905.0	COG0747@1|root,COG0747@2|Bacteria,1MUZH@1224|Proteobacteria,1RNES@1236|Gammaproteobacteria,1XIX9@135619|Oceanospirillales	135619|Oceanospirillales	E	extracellular solute-binding protein, family 5	-	-	-	ko:K02035,ko:K12368	ko02010,ko02024,ko02030,map02010,map02024,map02030	M00239,M00324	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
k141_421_2	400668.Mmwyl1_0113	8.73e-145	414.0	COG0601@1|root,COG0601@2|Bacteria,1MU8Z@1224|Proteobacteria,1RNJ1@1236|Gammaproteobacteria,1XIPB@135619|Oceanospirillales	135619|Oceanospirillales	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02033,ko:K12369	ko02010,ko02024,map02010,map02024	M00239,M00324	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
k141_109_2	536227.CcarbDRAFT_0102	1.04e-21	94.4	COG0655@1|root,COG0655@2|Bacteria,1UYQ4@1239|Firmicutes,249HT@186801|Clostridia,36FHX@31979|Clostridiaceae	186801|Clostridia	S	PFAM NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
k141_2075_1	1179226.AJXO01000019_gene1531	1.3e-12	68.9	COG1228@1|root,COG1228@2|Bacteria,1TQQ0@1239|Firmicutes,4HDKW@91061|Bacilli,4GYDQ@90964|Staphylococcaceae	91061|Bacilli	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
k141_110_1	485913.Krac_5072	2.76e-64	210.0	COG0673@1|root,COG0673@2|Bacteria,2G7RI@200795|Chloroflexi	200795|Chloroflexi	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
k141_2076_1	870967.VIS19158_09577	5.92e-74	235.0	COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,1RQ86@1236|Gammaproteobacteria,1XTCY@135623|Vibrionales	135623|Vibrionales	U	general secretion pathway protein	epsF	GO:0002790,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015628,GO:0015833,GO:0016020,GO:0032940,GO:0033036,GO:0042886,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098776	-	ko:K02455	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSF
k141_422_1	406124.ACPC01000022_gene4274	1.8e-67	219.0	COG0012@1|root,COG0012@2|Bacteria,1TPRK@1239|Firmicutes,4H9SQ@91061|Bacilli,1ZBUI@1386|Bacillus	91061|Bacilli	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0044424,GO:0044464	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
k141_2410_1	1265505.ATUG01000003_gene761	0.0	986.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MQ0@68525|delta/epsilon subdivisions,2WISW@28221|Deltaproteobacteria,2MIUG@213118|Desulfobacterales	28221|Deltaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k141_2410_3	1121396.KB893061_gene2717	1.18e-53	172.0	COG0780@1|root,COG0780@2|Bacteria,1MW0M@1224|Proteobacteria,42RDZ@68525|delta/epsilon subdivisions,2WQ4Z@28221|Deltaproteobacteria,2MK4R@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)	queF	-	1.7.1.13	ko:K06879,ko:K09457	ko00790,ko01100,map00790,map01100	-	R07605	RC01875	ko00000,ko00001,ko01000,ko03016	-	-	-	QueF
k141_2410_4	439235.Dalk_3203	1.3e-129	380.0	COG0042@1|root,COG0042@2|Bacteria,1MV5V@1224|Proteobacteria,42N3M@68525|delta/epsilon subdivisions,2WKM7@28221|Deltaproteobacteria,2MIXT@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	nifR3	-	-	ko:K05540	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Dus
k141_2410_5	933262.AXAM01000017_gene3108	2.94e-71	228.0	COG1533@1|root,COG1533@2|Bacteria,1Q22I@1224|Proteobacteria,42SVJ@68525|delta/epsilon subdivisions,2WPAY@28221|Deltaproteobacteria,2MIXI@213118|Desulfobacterales	28221|Deltaproteobacteria	L	Domain of unknown function (DUF1848)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1848
k141_2410_6	243231.GSU3079	2.37e-24	97.1	2E47B@1|root,32Z37@2|Bacteria,1NC7T@1224|Proteobacteria,42VYF@68525|delta/epsilon subdivisions,2WRN2@28221|Deltaproteobacteria,43VKY@69541|Desulfuromonadales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_3781_1	1173020.Cha6605_1068	7.14e-88	272.0	COG4886@1|root,COG4886@2|Bacteria,1GD11@1117|Cyanobacteria	1117|Cyanobacteria	S	Wd-40 repeat	-	-	-	-	-	-	-	-	-	-	-	-	LRR_6
k141_2078_1	1304885.AUEY01000010_gene1638	9.6e-66	214.0	COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,42MQI@68525|delta/epsilon subdivisions,2WN1S@28221|Deltaproteobacteria,2MJMW@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Aminotransferase class I and II	-	-	2.6.1.2	ko:K00814	ko00220,ko00250,ko00710,ko01100,ko01120,ko01200,ko01210,ko01230,map00220,map00250,map00710,map01100,map01120,map01200,map01210,map01230	M00171	R00258	RC00006,RC00008	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
k141_2078_2	297246.lpp1764	1.35e-10	63.9	COG2137@1|root,COG2137@2|Bacteria,1N6P6@1224|Proteobacteria,1SCMF@1236|Gammaproteobacteria,1JEHU@118969|Legionellales	118969|Legionellales	S	Modulates RecA activity	recX	-	-	ko:K03565	-	-	-	-	ko00000,ko03400	-	-	-	RecX
k141_3782_1	522772.Dacet_0971	4.48e-52	186.0	COG0612@1|root,COG0612@2|Bacteria	2|Bacteria	L	Peptidase, M16	pqqL	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
k141_4472_1	1122599.AUGR01000008_gene2571	8.88e-42	146.0	COG0726@1|root,COG0726@2|Bacteria,1MWMZ@1224|Proteobacteria,1RREJ@1236|Gammaproteobacteria,1XN90@135619|Oceanospirillales	135619|Oceanospirillales	G	Domain of unknown function (DUF3473)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3473,Polysacc_deac_1
k141_4472_2	1328313.DS2_04855	4.89e-145	430.0	COG2148@1|root,COG2148@2|Bacteria,1MV6W@1224|Proteobacteria,1RMMN@1236|Gammaproteobacteria,464MI@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	COG2148 Sugar transferases involved in lipopolysaccharide synthesis	lthA	-	-	-	-	-	-	-	-	-	-	-	Bac_transf,CoA_binding_3
k141_4472_3	1328313.DS2_04860	1.89e-93	279.0	COG1596@1|root,COG1596@2|Bacteria,1RFBH@1224|Proteobacteria,1S35N@1236|Gammaproteobacteria,464WW@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	COG1596 Periplasmic protein involved in polysaccharide export	wza	-	-	ko:K01991	ko02026,map02026	-	-	-	ko00000,ko00001,ko02000	1.B.18	-	-	Poly_export,SLBB
k141_4472_4	1120970.AUBZ01000003_gene167	6.94e-172	501.0	COG3206@1|root,COG3206@2|Bacteria,1MVBX@1224|Proteobacteria,1RXY8@1236|Gammaproteobacteria,465VX@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	protein involved in exopolysaccharide biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	GNVR,Wzz
k141_4472_5	1120970.AUBZ01000003_gene166	1.9e-72	246.0	COG0489@1|root,COG0489@2|Bacteria,1MVI9@1224|Proteobacteria,1RNB0@1236|Gammaproteobacteria,4649B@72275|Alteromonadaceae	1236|Gammaproteobacteria	D	COG0489 ATPases involved in chromosome partitioning	-	-	2.7.10.1	ko:K08252	-	-	-	-	ko00000,ko01000	-	-	-	AAA_31
k141_4472_6	1120970.AUBZ01000003_gene164	2.54e-26	104.0	COG3267@1|root,COG3267@2|Bacteria,1MU3G@1224|Proteobacteria,1RMI0@1236|Gammaproteobacteria,465NU@72275|Alteromonadaceae	1236|Gammaproteobacteria	U	general secretion pathway protein	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22
k141_112_1	223926.28807465	6.7e-110	331.0	COG3203@1|root,COG3203@2|Bacteria,1QTID@1224|Proteobacteria,1SWVI@1236|Gammaproteobacteria,1XSFV@135623|Vibrionales	135623|Vibrionales	M	COG3203 Outer membrane protein (porin)	ompU	GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944	-	ko:K08720	ko01501,ko05111,map01501,map05111	-	-	-	ko00000,ko00001,ko02000	1.B.1.2.1	-	-	Porin_1,Porin_4
k141_112_2	796620.VIBC2010_01943	2.19e-171	496.0	COG2027@1|root,COG2027@2|Bacteria,1MW40@1224|Proteobacteria,1RP8V@1236|Gammaproteobacteria,1XUAV@135623|Vibrionales	135623|Vibrionales	M	COG2027 D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 4)	dacB	-	3.4.16.4	ko:K07259	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S13
k141_3111_1	223926.28806225	9.58e-149	436.0	COG0076@1|root,COG0076@2|Bacteria,1MWUX@1224|Proteobacteria,1RQ8G@1236|Gammaproteobacteria,1XTEY@135623|Vibrionales	135623|Vibrionales	E	COG0076 Glutamate decarboxylase and related PLP-dependent proteins	-	GO:0003674,GO:0003824,GO:0004068,GO:0016829,GO:0016830,GO:0016831	4.1.1.15	ko:K01580	ko00250,ko00410,ko00430,ko00650,ko01100,ko01110,ko01120,ko02024,ko04727,ko04940,map00250,map00410,map00430,map00650,map01100,map01110,map01120,map02024,map04727,map04940	M00027	R00261,R00489,R01682,R02466	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Pyridoxal_deC
k141_3111_3	55601.VANGNB10_cI1048	2.13e-194	551.0	COG1454@1|root,COG1454@2|Bacteria,1MVPH@1224|Proteobacteria,1S1W6@1236|Gammaproteobacteria,1XTZE@135623|Vibrionales	135623|Vibrionales	C	alcohol dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Fe-ADH
k141_2411_1	675813.VIB_001612	2.47e-275	756.0	COG0304@1|root,COG0304@2|Bacteria,1MU1X@1224|Proteobacteria,1RMDE@1236|Gammaproteobacteria,1XSPH@135623|Vibrionales	135623|Vibrionales	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabF	GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:0072330,GO:1901576	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
k141_3785_2	177437.HRM2_00090	4.58e-41	147.0	COG0820@1|root,COG0820@2|Bacteria,1R67K@1224|Proteobacteria,42PCI@68525|delta/epsilon subdivisions,2WJI5@28221|Deltaproteobacteria,2MIKV@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
k141_424_1	1238450.VIBNISOn1_960014	1.5e-05	45.8	COG0628@1|root,COG0628@2|Bacteria,1MW0B@1224|Proteobacteria,1RPVP@1236|Gammaproteobacteria,1XV05@135623|Vibrionales	135623|Vibrionales	S	AI-2E family transporter	perM	-	-	ko:K03548	-	-	-	-	ko00000,ko02000	2.A.86.1	-	-	AI-2E_transport
k141_424_2	55601.VANGNB10_cI1966	3.4e-213	604.0	COG4783@1|root,COG4783@2|Bacteria,1MVFV@1224|Proteobacteria,1RP5S@1236|Gammaproteobacteria,1XUZK@135623|Vibrionales	135623|Vibrionales	S	Functions as both a chaperone and a metalloprotease. Maintains the integrity of the outer membrane by promoting either the assembly or the elimination of outer membrane proteins, depending on their folding state	yfgC	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48,TPR_19,TPR_8
k141_424_3	1219080.VEZ01S_01_00850	4.39e-50	161.0	COG1393@1|root,COG1393@2|Bacteria,1MZ4Z@1224|Proteobacteria,1S8XH@1236|Gammaproteobacteria,1XXT8@135623|Vibrionales	135623|Vibrionales	C	COG1393 Arsenate reductase and related proteins, glutaredoxin family	arsC	-	1.20.4.1	ko:K00537	-	-	-	-	ko00000,ko01000	-	-	-	ArsC
k141_424_4	55601.VANGNB10_cI1970c	3.36e-78	248.0	COG3249@1|root,COG3249@2|Bacteria,1N0PD@1224|Proteobacteria,1S9C4@1236|Gammaproteobacteria,1XU1W@135623|Vibrionales	135623|Vibrionales	S	protein conserved in bacteria	VV2512	-	-	ko:K09938	-	-	-	-	ko00000	-	-	-	DUF2066
k141_114_1	109478.XP_005879749.1	1.37e-05	50.1	COG0350@1|root,KOG4062@2759|Eukaryota,3A29E@33154|Opisthokonta,3BPUX@33208|Metazoa,3D0M7@33213|Bilateria,47Z3U@7711|Chordata,498MH@7742|Vertebrata,3JAU2@40674|Mammalia,4KYZA@9397|Chiroptera	33208|Metazoa	L	Methyltransferase	MGMT	GO:0001101,GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003824,GO:0003908,GO:0005488,GO:0005509,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006282,GO:0006304,GO:0006305,GO:0006306,GO:0006307,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006979,GO:0007275,GO:0007584,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0009008,GO:0009314,GO:0009605,GO:0009628,GO:0009636,GO:0009888,GO:0009893,GO:0009987,GO:0009991,GO:0010033,GO:0010212,GO:0010243,GO:0010604,GO:0010941,GO:0014070,GO:0016740,GO:0016741,GO:0016765,GO:0019219,GO:0019222,GO:0030154,GO:0030162,GO:0030855,GO:0030879,GO:0031323,GO:0031325,GO:0031667,GO:0031974,GO:0031981,GO:0032259,GO:0032501,GO:0032502,GO:0033273,GO:0033554,GO:0034599,GO:0034641,GO:0035510,GO:0042221,GO:0042493,GO:0042981,GO:0043066,GO:0043067,GO:0043069,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043281,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044464,GO:0044728,GO:0045471,GO:0045739,GO:0045935,GO:0046483,GO:0046677,GO:0046872,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048584,GO:0048731,GO:0048732,GO:0048856,GO:0048869,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051052,GO:0051054,GO:0051171,GO:0051173,GO:0051246,GO:0051336,GO:0051593,GO:0051716,GO:0052547,GO:0052548,GO:0060255,GO:0060429,GO:0060548,GO:0060644,GO:0061180,GO:0065007,GO:0065009,GO:0070013,GO:0070887,GO:0071214,GO:0071310,GO:0071407,GO:0071478,GO:0071479,GO:0071704,GO:0080090,GO:0080134,GO:0080135,GO:0090304,GO:0097159,GO:0097305,GO:0104004,GO:0140097,GO:1901360,GO:1901363,GO:1901698,GO:1901700,GO:2000116,GO:2000779,GO:2000781,GO:2001020,GO:2001022	2.1.1.63	ko:K00567	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_binding_1,Methyltransf_1N
k141_114_2	1121864.OMO_01560	2.36e-10	63.5	COG0242@1|root,COG0242@2|Bacteria,1V70B@1239|Firmicutes,4HJTW@91061|Bacilli,4AZKP@81852|Enterococcaceae	91061|Bacilli	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def1	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
k141_114_3	1537917.JU82_07855	8.54e-15	79.0	COG1131@1|root,COG1131@2|Bacteria,1R934@1224|Proteobacteria	1224|Proteobacteria	V	(ABC) transporter	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_3112_1	317619.ANKN01000051_gene687	2.8e-46	177.0	COG0553@1|root,COG0553@2|Bacteria,1G0S7@1117|Cyanobacteria,1MM7N@1212|Prochloraceae	1117|Cyanobacteria	KL	Alternative locus ID	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,SNF2_N
k141_2413_1	96561.Dole_1156	7.29e-74	252.0	COG3209@1|root,COG3485@1|root,COG3209@2|Bacteria,COG3485@2|Bacteria,1MVV1@1224|Proteobacteria,43AER@68525|delta/epsilon subdivisions,2X5UG@28221|Deltaproteobacteria,2MN6Q@213118|Desulfobacterales	28221|Deltaproteobacteria	GM	PFAM NHL repeat containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,NHL,RHS_repeat
k141_5130_44	234831.PSM_A1166	2.75e-97	286.0	COG0655@1|root,COG0655@2|Bacteria,1MW7N@1224|Proteobacteria,1RPXM@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	NADPH-dependent FMN reductase	wrbA	-	1.6.5.2	ko:K03809	ko00130,ko01110,map00130,map01110	-	R02964,R03643,R03816	RC00819	ko00000,ko00001,ko01000	-	-	-	FMN_red,Flavodoxin_5
k141_5130_45	1224318.DT73_15665	4.33e-45	160.0	COG1396@1|root,COG1396@2|Bacteria,1MUG2@1224|Proteobacteria,1RQP5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	transcriptional	-	-	-	-	-	-	-	-	-	-	-	-	HTH_31
k141_5130_46	314292.VAS14_13109	1.87e-144	426.0	COG0477@1|root,COG0477@2|Bacteria,1MWXZ@1224|Proteobacteria,1RPIM@1236|Gammaproteobacteria,1XYNE@135623|Vibrionales	135623|Vibrionales	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
k141_5130_47	1219065.VPR01S_01_03190	2.05e-81	248.0	COG2872@1|root,COG2872@2|Bacteria,1MY0P@1224|Proteobacteria,1SBU1@1236|Gammaproteobacteria,1XVYU@135623|Vibrionales	135623|Vibrionales	S	tRNA synthetases class II (A)	-	-	-	-	-	-	-	-	-	-	-	-	tRNA-synt_2c,tRNA_SAD
k141_5130_48	1515746.HR45_00950	6.31e-175	495.0	COG3507@1|root,COG3507@2|Bacteria,1R3V6@1224|Proteobacteria,1RPI5@1236|Gammaproteobacteria,2QB3X@267890|Shewanellaceae	1236|Gammaproteobacteria	G	Belongs to the glycosyl hydrolase 43 family	abnA	-	3.2.1.99	ko:K06113	-	-	-	-	ko00000,ko01000	-	GH43	-	Glyco_hydro_43
k141_5130_49	748449.Halha_1741	4.89e-285	790.0	COG1070@1|root,COG1070@2|Bacteria,1TP91@1239|Firmicutes,24A4Z@186801|Clostridia	186801|Clostridia	G	Carbohydrate kinase, FGGY family protein	araB	-	-	-	-	-	-	-	-	-	-	-	FGGY_C,FGGY_N
k141_5130_50	672.VV93_v1c44450	1.02e-122	361.0	COG0583@1|root,COG0583@2|Bacteria,1MWY0@1224|Proteobacteria,1RNMN@1236|Gammaproteobacteria,1XV8F@135623|Vibrionales	135623|Vibrionales	K	Transcriptional regulator	-	-	-	ko:K13636	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,LysR_substrate
k141_5130_51	223926.28810097	1.2e-260	721.0	COG1486@1|root,COG1486@2|Bacteria,1NI6G@1224|Proteobacteria,1RPG8@1236|Gammaproteobacteria,1XSYS@135623|Vibrionales	135623|Vibrionales	G	COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases	-	-	3.2.1.86	ko:K01222	ko00010,ko00500,map00010,map00500	-	R00839,R05133,R05134	RC00049,RC00171,RC00714	ko00000,ko00001,ko01000	-	GT4	-	Glyco_hydro_4,Glyco_hydro_4C
k141_5130_52	1348635.BBJY01000001_gene2528	4.9e-136	399.0	COG0701@1|root,COG0701@2|Bacteria,1MUN8@1224|Proteobacteria,1RSPM@1236|Gammaproteobacteria,1XSCM@135623|Vibrionales	135623|Vibrionales	S	Predicted permease	-	-	-	ko:K07089	-	-	-	-	ko00000	-	-	-	ArsP_1
k141_4194_2	1116375.VEJY3_06810	4.11e-180	513.0	COG0477@1|root,COG0477@2|Bacteria,1MU46@1224|Proteobacteria,1T3VZ@1236|Gammaproteobacteria,1XV7D@135623|Vibrionales	135623|Vibrionales	EGP	of the major facilitator superfamily	-	-	-	ko:K03762	-	-	-	-	ko00000,ko02000	2.A.1.6.4	-	-	MFS_1,Sugar_tr
k141_1867_1	575788.VS_0673	0.0	1353.0	COG1330@1|root,COG1330@2|Bacteria,1MWTI@1224|Proteobacteria,1RNT0@1236|Gammaproteobacteria,1XTXU@135623|Vibrionales	135623|Vibrionales	L	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity	recC	-	3.1.11.5	ko:K03583	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_V_gamma
k141_1867_2	672.VV93_v1c23290	0.0	1449.0	COG1074@1|root,COG1074@2|Bacteria,1MUTF@1224|Proteobacteria,1RPC6@1236|Gammaproteobacteria,1XTTM@135623|Vibrionales	135623|Vibrionales	L	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA	recB	-	3.1.11.5	ko:K03582	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
k141_1867_3	55601.VANGNB10_cI2099c	4.21e-247	707.0	COG0507@1|root,COG0507@2|Bacteria,1MW43@1224|Proteobacteria,1RPA0@1236|Gammaproteobacteria,1XTSQ@135623|Vibrionales	135623|Vibrionales	L	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD	recD	-	3.1.11.5	ko:K03581	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AAA_30,UvrD_C_2
k141_1867_4	1136163.M565_ctg1P1859	9.73e-21	83.6	2B2RH@1|root,31VBN@2|Bacteria,1QT8K@1224|Proteobacteria,1TIC2@1236|Gammaproteobacteria,1XYUI@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_1867_5	55601.VANGNB10_cI2098	9.17e-256	709.0	COG0548@1|root,COG1246@1|root,COG0548@2|Bacteria,COG1246@2|Bacteria,1MUUP@1224|Proteobacteria,1RMV5@1236|Gammaproteobacteria,1XSV8@135623|Vibrionales	135623|Vibrionales	E	Amino-acid acetyltransferase	argA	GO:0003674,GO:0003824,GO:0004042,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.3.1.1	ko:K14682	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,Acetyltransf_1
k141_1867_6	675815.VOA_002639	1.47e-193	545.0	COG2821@1|root,COG2821@2|Bacteria,1MXD4@1224|Proteobacteria,1RP7K@1236|Gammaproteobacteria,1XTDJ@135623|Vibrionales	135623|Vibrionales	M	membrane-bound lytic murein transglycosylase	mltA	GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009253,GO:0030203,GO:0043170,GO:0071704,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575	-	ko:K08304	-	-	-	-	ko00000,ko01000,ko01011	-	GH102	-	3D,MltA
k141_3870_1	1187848.AJYQ01000076_gene1703	1.66e-134	415.0	COG3008@1|root,COG3008@2|Bacteria,1MU1T@1224|Proteobacteria,1RN89@1236|Gammaproteobacteria,1XTE9@135623|Vibrionales	135623|Vibrionales	Q	Paraquat-inducible protein B	-	-	-	-	-	-	-	-	-	-	-	-	MlaD
k141_3870_2	617140.AJZE01000058_gene1177	5.94e-250	696.0	COG0144@1|root,COG3270@1|root,COG0144@2|Bacteria,COG3270@2|Bacteria,1NAY1@1224|Proteobacteria,1RP74@1236|Gammaproteobacteria,1XSE4@135623|Vibrionales	135623|Vibrionales	J	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA	rsmF	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.178	ko:K11392	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F,Methyltr_RsmF_N,Methyltranf_PUA
k141_3199_1	1515746.HR45_08725	7.55e-59	188.0	COG4659@1|root,COG4659@2|Bacteria,1RDEP@1224|Proteobacteria,1RPAD@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Part of a membrane complex involved in electron transport	rnfG	-	-	ko:K03612	-	-	-	-	ko00000	-	-	-	FMN_bind
k141_3199_2	1348635.BBJY01000001_gene2378	2.85e-163	465.0	COG4658@1|root,COG4658@2|Bacteria,1MVY6@1224|Proteobacteria,1RX39@1236|Gammaproteobacteria,1Y041@135623|Vibrionales	135623|Vibrionales	C	NQR2, RnfD, RnfE family	-	-	-	ko:K03614	-	-	-	-	ko00000	-	-	-	NQR2_RnfD_RnfE
k141_3871_1	1219065.VPR01S_23_00560	1.03e-95	285.0	COG1842@1|root,COG1842@2|Bacteria,1NC7S@1224|Proteobacteria,1RS0G@1236|Gammaproteobacteria,1XUJH@135623|Vibrionales	135623|Vibrionales	KT	COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription	pspA	-	-	ko:K03969	-	-	-	-	ko00000	-	-	-	PspA_IM30
k141_3871_2	870967.VIS19158_15439	5.89e-22	87.8	2CJWQ@1|root,32YI2@2|Bacteria,1N769@1224|Proteobacteria,1SCNV@1236|Gammaproteobacteria,1XYAE@135623|Vibrionales	135623|Vibrionales	S	Phage shock protein B	pspB	-	-	ko:K03970	-	-	-	-	ko00000,ko02048	-	-	-	PspB
k141_3871_3	1517681.HW45_16615	3.81e-21	86.3	COG1983@1|root,COG1983@2|Bacteria,1N085@1224|Proteobacteria,1S98J@1236|Gammaproteobacteria,1XXB4@135623|Vibrionales	135623|Vibrionales	KT	phage shock protein C	pspC	-	-	ko:K03973	-	-	-	-	ko00000,ko02048,ko03000	-	-	-	PspC
k141_2463_1	1123355.JHYO01000008_gene2625	3.68e-86	269.0	COG0420@1|root,COG0420@2|Bacteria,1MVV6@1224|Proteobacteria,2TV97@28211|Alphaproteobacteria,36YN7@31993|Methylocystaceae	28211|Alphaproteobacteria	L	Type 5 capsule protein repressor C-terminal domain	sbcD	-	-	ko:K03547	-	-	-	-	ko00000,ko03400	-	-	-	Metallophos,SbcD_C
k141_2463_2	338966.Ppro_2570	1.47e-58	204.0	COG0419@1|root,COG0419@2|Bacteria,1MVTQ@1224|Proteobacteria,42NVV@68525|delta/epsilon subdivisions,2WJIZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	ATPase involved in DNA repair	sbcC	-	-	ko:K03546	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,SbcCD_C
k141_4195_1	1304885.AUEY01000068_gene1411	1.13e-158	471.0	COG0243@1|root,COG0243@2|Bacteria,1NR6J@1224|Proteobacteria,42QKW@68525|delta/epsilon subdivisions,2WKH1@28221|Deltaproteobacteria,2MMHI@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
k141_4195_2	1379281.AVAG01000111_gene947	1.95e-35	133.0	COG0303@1|root,COG2191@1|root,COG0303@2|Bacteria,COG2191@2|Bacteria,1MYKY@1224|Proteobacteria,42NIJ@68525|delta/epsilon subdivisions,2WJ0M@28221|Deltaproteobacteria,2M7RP@213115|Desulfovibrionales	28221|Deltaproteobacteria	CH	PFAM Formylmethanofuran dehydrogenase, subunit E region	-	-	1.2.7.12	ko:K11261	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00567	R03015,R08060,R11743	RC00197,RC00323	ko00000,ko00001,ko00002,ko01000	-	-	-	FmdE,MoCF_biosynth
k141_4195_3	1121324.CLIT_10c04630	0.000434	43.1	COG0303@1|root,COG0303@2|Bacteria,1TP7F@1239|Firmicutes,247TZ@186801|Clostridia,25QHE@186804|Peptostreptococcaceae	186801|Clostridia	H	Probable molybdopterin binding domain	-	-	-	-	-	-	-	-	-	-	-	-	MoCF_biosynth
k141_1200_1	1122207.MUS1_02075	1.07e-80	244.0	COG1268@1|root,COG1268@2|Bacteria,1RD2B@1224|Proteobacteria,1S4CR@1236|Gammaproteobacteria,1XKK0@135619|Oceanospirillales	135619|Oceanospirillales	S	BioY family	-	-	-	-	-	-	-	-	-	-	-	-	BioY
k141_1200_2	1122207.MUS1_02080	1.25e-113	333.0	COG4285@1|root,COG4285@2|Bacteria,1N4UC@1224|Proteobacteria,1SJ9Z@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Biotin-protein ligase, N terminal	-	-	-	-	-	-	-	-	-	-	-	-	BPL_N
k141_1200_3	1191299.AJYX01000099_gene785	2.13e-63	196.0	COG3205@1|root,COG3205@2|Bacteria,1N85D@1224|Proteobacteria,1SCCN@1236|Gammaproteobacteria,1XXCR@135623|Vibrionales	135623|Vibrionales	S	Predicted membrane protein (DUF2061)	VP2647	-	-	-	-	-	-	-	-	-	-	-	DUF2061
k141_1200_4	35703.DQ02_01670	1.1e-57	186.0	COG1443@1|root,COG1443@2|Bacteria,1R9YJ@1224|Proteobacteria,1S6ZT@1236|Gammaproteobacteria,3WXKJ@544|Citrobacter	1236|Gammaproteobacteria	I	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)	idi	GO:0003674,GO:0003824,GO:0004452,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016853,GO:0016860,GO:0016863,GO:0019637,GO:0033554,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044464,GO:0046490,GO:0050896,GO:0051716,GO:0071704,GO:0090407,GO:1901576	4.1.1.33,5.3.3.2	ko:K01597,ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00095,M00096,M00364,M00365,M00366,M00367	R01121,R01123	RC00453,RC00455	ko00000,ko00001,ko00002,ko01000	-	-	iECH74115_1262.ECH74115_4179,iECIAI1_1343.ECIAI1_3008,iECO103_1326.ECO103_3464,iECSP_1301.ECSP_3858,iECs_1301.ECs3761,iEcE24377_1341.EcE24377A_3215,iG2583_1286.G2583_3542,iSFV_1184.SFV_2937,iSF_1195.SF2875,iSFxv_1172.SFxv_3153,iSSON_1240.SSON_3042,iS_1188.S3074,iZ_1308.Z4227	NUDIX
k141_1200_5	1218086.BBNB01000015_gene2128	3.64e-56	179.0	COG3787@1|root,COG3787@2|Bacteria,1RH76@1224|Proteobacteria,1S6F1@1236|Gammaproteobacteria,3WY91@544|Citrobacter	1236|Gammaproteobacteria	S	Belongs to the UPF0306 family	yhbP	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K09979	-	-	-	-	ko00000	-	-	-	Putative_PNPOx
k141_1201_1	1265505.ATUG01000002_gene1967	2.52e-54	179.0	2DBAY@1|root,2Z84S@2|Bacteria,1R7V4@1224|Proteobacteria,42MQE@68525|delta/epsilon subdivisions,2WJGC@28221|Deltaproteobacteria,2MJ24@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF1835
k141_3201_1	1265505.ATUG01000001_gene3201	7.35e-94	285.0	COG0765@1|root,COG0765@2|Bacteria,1R4RU@1224|Proteobacteria,42PW7@68525|delta/epsilon subdivisions,2WK9J@28221|Deltaproteobacteria,2MJID@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02029	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	BPD_transp_1
k141_3201_2	207559.Dde_3070	1.37e-33	123.0	COG0834@1|root,COG0834@2|Bacteria,1MWDK@1224|Proteobacteria,42NVT@68525|delta/epsilon subdivisions,2WJ9C@28221|Deltaproteobacteria,2M9NJ@213115|Desulfovibrionales	28221|Deltaproteobacteria	ET	extracellular solute-binding protein, family 3	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
k141_3873_1	526222.Desal_0438	9.49e-158	459.0	COG2710@1|root,COG2710@2|Bacteria,1MWSX@1224|Proteobacteria,42MPD@68525|delta/epsilon subdivisions,2WJ05@28221|Deltaproteobacteria,2M8X1@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	Belongs to the NifD NifK NifE NifN family	-	-	-	ko:K02592	-	-	-	-	ko00000	-	-	-	Oxidored_nitro
k141_5184_2	1236501.BAJU01000001_gene168	3e-16	73.6	COG3042@1|root,COG3042@2|Bacteria,1N8JF@1224|Proteobacteria,2UMTB@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Domain of unknown function (DUF333)	-	-	-	ko:K09712	-	-	-	-	ko00000	-	-	-	DUF333
k141_5184_3	55601.VANGNB10_cI2005	2.6e-183	520.0	28KVI@1|root,2ZAC4@2|Bacteria,1RBAQ@1224|Proteobacteria,1S3C3@1236|Gammaproteobacteria,1XV1Z@135623|Vibrionales	135623|Vibrionales	N	Flagellar assembly protein T, C-terminal domain	flgT	-	-	-	-	-	-	-	-	-	-	-	FlgT_C,FlgT_M,FlgT_N
k141_5184_4	675806.VII_001628	7.58e-129	368.0	COG5616@1|root,COG5616@2|Bacteria,1R4DP@1224|Proteobacteria,1SAIF@1236|Gammaproteobacteria,1XTPR@135623|Vibrionales	135623|Vibrionales	S	Integral membrane protein	VC2207	-	-	-	-	-	-	-	-	-	-	-	-
k141_5184_5	1219065.VPR01S_10_00210	5e-69	211.0	COG3018@1|root,COG3018@2|Bacteria,1RIA2@1224|Proteobacteria,1SE4B@1236|Gammaproteobacteria,1XWZ3@135623|Vibrionales	135623|Vibrionales	S	LPP20 lipoprotein	rim	-	-	ko:K09860	-	-	-	-	ko00000	-	-	-	LPP20
k141_5184_6	1051646.VITU9109_03187	2.42e-52	169.0	COG3418@1|root,33AIS@2|Bacteria,1NH78@1224|Proteobacteria,1SGPM@1236|Gammaproteobacteria,1XXGG@135623|Vibrionales	135623|Vibrionales	NOU	FlgN protein	flgN	-	-	ko:K02399	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FlgN
k141_5184_7	243277.VC_2204	1.46e-32	116.0	COG2747@1|root,COG2747@2|Bacteria,1NGJA@1224|Proteobacteria,1SGQ4@1236|Gammaproteobacteria,1XYEH@135623|Vibrionales	135623|Vibrionales	N	COG2747 Negative regulator of flagellin synthesis (anti-sigma28 factor)	flgM	-	-	ko:K02398	ko02020,ko02025,ko02026,ko02040,map02020,map02025,map02026,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FlgM
k141_5184_8	243277.VC_2203	1.48e-106	315.0	COG1261@1|root,COG1261@2|Bacteria,1N1SA@1224|Proteobacteria,1S8SQ@1236|Gammaproteobacteria,1XSM2@135623|Vibrionales	135623|Vibrionales	N	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly	flgA	-	-	ko:K02386	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	ChapFlgA
k141_5184_17	1187848.AJYQ01000102_gene1019	6.65e-124	360.0	COG2063@1|root,COG2063@2|Bacteria,1RDEY@1224|Proteobacteria,1S3XK@1236|Gammaproteobacteria,1XUAA@135623|Vibrionales	135623|Vibrionales	N	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation	flgH	GO:0003674,GO:0005198,GO:0005575,GO:0005623,GO:0009288,GO:0009425,GO:0042995,GO:0043226,GO:0043228,GO:0044422,GO:0044461,GO:0044463,GO:0044464	-	ko:K02393	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FlgH
k141_5184_19	1348635.BBJY01000002_gene3375	6.52e-134	389.0	COG1705@1|root,COG3951@1|root,COG1705@2|Bacteria,COG3951@2|Bacteria,1MX2W@1224|Proteobacteria,1RPGY@1236|Gammaproteobacteria,1XSX3@135623|Vibrionales	135623|Vibrionales	N	Flagellar rod assembly protein muramidase FlgJ	flgJ	GO:0003674,GO:0005198	-	ko:K02395	-	-	-	-	ko00000,ko02035	-	-	-	Glucosaminidase,Rod-binding
k141_5184_20	1348635.BBJY01000002_gene3374	0.0	913.0	COG1256@1|root,COG1256@2|Bacteria,1MV2M@1224|Proteobacteria,1RMEA@1236|Gammaproteobacteria,1XU4C@135623|Vibrionales	135623|Vibrionales	N	flagellar hook-associated protein	flgK	-	-	ko:K02396	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod,Flg_bbr_C
k141_5184_21	243277.VC_2190	2.82e-212	595.0	COG1344@1|root,COG1344@2|Bacteria,1PJUJ@1224|Proteobacteria,1RPNR@1236|Gammaproteobacteria,1XTKN@135623|Vibrionales	135623|Vibrionales	N	COG1344 Flagellin and related hook-associated proteins	flgL	-	-	ko:K02397	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flagellin_C,Flagellin_N
k141_2464_1	335992.SAR11_0935	8.49e-122	377.0	COG0845@1|root,COG1994@1|root,COG0845@2|Bacteria,COG1994@2|Bacteria,1MW9I@1224|Proteobacteria,2U0H8@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	Peptidase, M50 family	-	-	-	ko:K16922	-	-	-	-	ko00000,ko01002	-	-	-	Biotin_lipoyl_2,HlyD_3
k141_4197_1	265072.Mfla_2628	4.4e-63	228.0	COG0715@1|root,COG2202@1|root,COG5001@1|root,COG0715@2|Bacteria,COG2202@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,2KMBP@206350|Nitrosomonadales	206350|Nitrosomonadales	T	PFAM EAL domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF,NMT1,PAS_3,PAS_9
k141_1482_1	745411.B3C1_10782	0.0	1791.0	COG2373@1|root,COG2373@2|Bacteria,1MV7J@1224|Proteobacteria,1RNRY@1236|Gammaproteobacteria,1J8TQ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Alpha-2-Macroglobulin	-	-	-	ko:K06894	-	-	-	-	ko00000	-	-	-	A2M,A2M_N,A2M_N_2,MG1,Thiol-ester_cl
k141_1482_2	1236542.BALM01000005_gene2588	2e-42	139.0	2DE9N@1|root,32U2Y@2|Bacteria,1N2MR@1224|Proteobacteria,1SA0N@1236|Gammaproteobacteria,2QCJ3@267890|Shewanellaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_1482_3	243277.VC_A0772	4.12e-211	592.0	COG0814@1|root,COG0814@2|Bacteria,1N35H@1224|Proteobacteria,1RNNC@1236|Gammaproteobacteria,1XSRG@135623|Vibrionales	135623|Vibrionales	U	tyrosine-specific transport protein	tyrP	-	-	ko:K03834	-	-	-	-	ko00000,ko02000	2.A.42.1.1	-	-	Trp_Tyr_perm
k141_1202_1	1232437.KL661955_gene2371	4.42e-75	236.0	COG3332@1|root,COG3332@2|Bacteria,1RDBS@1224|Proteobacteria,42QS8@68525|delta/epsilon subdivisions,2WMV7@28221|Deltaproteobacteria,2MJNJ@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Transport and Golgi organisation 2	-	-	-	-	-	-	-	-	-	-	-	-	TANGO2
k141_1202_2	1232437.KL661955_gene2370	6.22e-227	634.0	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,42MSR@68525|delta/epsilon subdivisions,2WIXG@28221|Deltaproteobacteria,2MIJC@213118|Desulfobacterales	28221|Deltaproteobacteria	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
k141_1203_1	1265505.ATUG01000001_gene3019	6.26e-132	386.0	COG0397@1|root,COG0397@2|Bacteria,1MVK3@1224|Proteobacteria,42NTK@68525|delta/epsilon subdivisions,2WIV0@28221|Deltaproteobacteria,2MI7S@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Belongs to the UPF0061 (SELO) family	-	-	-	ko:K08997	-	-	-	-	ko00000	-	-	-	UPF0061
k141_1868_1	55601.VANGNB10_cI2358c	1.94e-205	585.0	COG0475@1|root,COG1226@1|root,COG0475@2|Bacteria,COG1226@2|Bacteria,1MV34@1224|Proteobacteria,1RNVR@1236|Gammaproteobacteria,1XSSX@135623|Vibrionales	135623|Vibrionales	P	Pore-forming subunit of a potassium efflux system that confers protection against electrophiles. Catalyzes K( ) H( ) antiport	kefB	-	-	ko:K11747	-	-	-	-	ko00000,ko02000	2.A.37.1.2	-	-	Na_H_Exchanger,TrkA_N
k141_1868_2	29495.EA26_19805	1.41e-86	261.0	COG1047@1|root,COG1047@2|Bacteria,1RD35@1224|Proteobacteria,1S3QR@1236|Gammaproteobacteria,1XSRK@135623|Vibrionales	135623|Vibrionales	G	COG1047 FKBP-type peptidyl-prolyl cis-trans isomerases 2	slyD	GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0006457,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0036211,GO:0042026,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:0140096,GO:1901564	5.2.1.8	ko:K03775	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C
k141_1868_3	55601.VANGNB10_cI2355c	7.31e-288	789.0	COG0104@1|root,COG0104@2|Bacteria,1MU5B@1224|Proteobacteria,1RNEW@1236|Gammaproteobacteria,1XU7G@135623|Vibrionales	135623|Vibrionales	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
k141_1868_4	1280001.BAOA01000039_gene2490	2.54e-104	306.0	COG0790@1|root,COG0790@2|Bacteria,1RE9M@1224|Proteobacteria,1RPR8@1236|Gammaproteobacteria,1XT10@135623|Vibrionales	135623|Vibrionales	N	flagellar protein motX	motX	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K21217	ko02040,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	Sel1
k141_4921_5	1219076.N646_2898	7.84e-132	380.0	COG2912@1|root,COG2912@2|Bacteria,1MVJQ@1224|Proteobacteria,1RQ7V@1236|Gammaproteobacteria,1XSET@135623|Vibrionales	135623|Vibrionales	S	Transglutaminase-like superfamily	ychA	-	-	-	-	-	-	-	-	-	-	-	TPR_9,Transglut_core2
k141_4921_6	1219077.VAZ01S_072_00050	2.54e-132	383.0	COG2890@1|root,COG2890@2|Bacteria,1MXCQ@1224|Proteobacteria,1RNGK@1236|Gammaproteobacteria,1XTR8@135623|Vibrionales	135623|Vibrionales	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif	prmC	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0032259,GO:0036009,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	Methyltransf_31
k141_1222_1	675813.VIB_001184	2.51e-105	317.0	COG3493@1|root,COG3493@2|Bacteria,1NKCA@1224|Proteobacteria,1RN6E@1236|Gammaproteobacteria,1XUGC@135623|Vibrionales	135623|Vibrionales	C	2-hydroxycarboxylate transporter family	-	-	-	-	-	-	-	-	-	-	-	-	2HCT
k141_1222_2	1191299.AJYX01000011_gene267	5.33e-104	307.0	2BVTQ@1|root,2Z7J9@2|Bacteria,1P01Z@1224|Proteobacteria,1RNNB@1236|Gammaproteobacteria,1XT57@135623|Vibrionales	135623|Vibrionales	S	Protein of unknown function (DUF2797)	LA2027	-	-	-	-	-	-	-	-	-	-	-	DUF2797
k141_3893_1	641107.CDLVIII_5310	2.83e-56	196.0	COG4467@1|root,COG4467@2|Bacteria,1VK8R@1239|Firmicutes,24979@186801|Clostridia	186801|Clostridia	S	Transposase IS66 family	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS66
k141_3893_3	1121403.AUCV01000045_gene1169	3.37e-151	430.0	2DBUF@1|root,2ZB5S@2|Bacteria,1NUFT@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	ko:K13409	ko02010,ko04626,map02010,map04626	M00339	-	-	ko00000,ko00001,ko00002,ko02000,ko02044	3.A.1.110	-	-	Asp_protease_2
k141_4922_1	675816.VIA_001150	5.65e-21	90.9	28IW1@1|root,2Z8UB@2|Bacteria,1N1QM@1224|Proteobacteria,1RR0J@1236|Gammaproteobacteria,1XSR0@135623|Vibrionales	135623|Vibrionales	S	F plasmid transfer operon, TraF, protein	-	-	-	-	-	-	-	-	-	-	-	-	TraF_2
k141_4922_2	511062.GU3_09530	6.21e-40	137.0	COG3223@1|root,COG3223@2|Bacteria,1N0MS@1224|Proteobacteria,1S9SN@1236|Gammaproteobacteria,1Y5WJ@135624|Aeromonadales	135624|Aeromonadales	S	Phosphate-starvation-inducible E	-	-	-	ko:K13256	-	-	-	-	ko00000	-	-	-	PsiE
k141_4922_3	314292.VAS14_05838	8.84e-33	123.0	COG0686@1|root,COG0686@2|Bacteria,1QTX1@1224|Proteobacteria,1T1JB@1236|Gammaproteobacteria,1XU10@135623|Vibrionales	135623|Vibrionales	C	Belongs to the AlaDH PNT family	ald	-	1.4.1.1	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	-	R00396	RC00008	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
k141_2829_4	595494.Tola_2869	7.46e-43	140.0	2DAFR@1|root,32TVC@2|Bacteria,1MZ92@1224|Proteobacteria,1S8Y1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	ParD-like antitoxin of type II bacterial toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	ParD_like
k141_2829_5	338963.Pcar_0528	1.96e-53	168.0	COG2026@1|root,COG2026@2|Bacteria,1N07K@1224|Proteobacteria,42V8I@68525|delta/epsilon subdivisions,2WS41@28221|Deltaproteobacteria	28221|Deltaproteobacteria	DJ	ParE-like toxin of type II bacterial toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	ParE-like_toxin
k141_543_1	95619.PM1_0221965	6.01e-22	99.4	COG1629@1|root,COG1629@2|Bacteria,1QV18@1224|Proteobacteria,1T2Q3@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	receptor	-	-	-	-	-	-	-	-	-	-	-	-	Plug,STN,TonB_dep_Rec
k141_2830_1	1540257.JQMW01000011_gene1512	1.73e-93	287.0	COG0531@1|root,COG0531@2|Bacteria,1TRFS@1239|Firmicutes,248WW@186801|Clostridia,36E79@31979|Clostridiaceae	186801|Clostridia	E	Amino acid permease family protein	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
k141_4923_1	345073.VC395_A0723	3.02e-116	352.0	COG4166@1|root,COG4166@2|Bacteria,1MUVU@1224|Proteobacteria,1RMA1@1236|Gammaproteobacteria,1XUMM@135623|Vibrionales	135623|Vibrionales	E	ABC-type oligopeptide transport system, periplasmic component	-	-	-	ko:K13893	ko02010,map02010	M00349	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.21,3.A.1.5.24	-	-	SBP_bac_5
k141_3214_1	1056512.D515_03082	2.1e-55	200.0	COG3209@1|root,COG3209@2|Bacteria,1MVV1@1224|Proteobacteria,1SKYM@1236|Gammaproteobacteria,1XW76@135623|Vibrionales	135623|Vibrionales	M	COG3209 Rhs family protein	-	-	-	-	-	-	-	-	-	-	-	-	Ntox15,RHS,RHS_repeat
k141_3214_3	1056512.D515_03082	2.41e-59	206.0	COG3209@1|root,COG3209@2|Bacteria,1MVV1@1224|Proteobacteria,1SKYM@1236|Gammaproteobacteria,1XW76@135623|Vibrionales	135623|Vibrionales	M	COG3209 Rhs family protein	-	-	-	-	-	-	-	-	-	-	-	-	Ntox15,RHS,RHS_repeat
k141_3214_4	1056512.D515_03082	1.37e-36	138.0	COG3209@1|root,COG3209@2|Bacteria,1MVV1@1224|Proteobacteria,1SKYM@1236|Gammaproteobacteria,1XW76@135623|Vibrionales	135623|Vibrionales	M	COG3209 Rhs family protein	-	-	-	-	-	-	-	-	-	-	-	-	Ntox15,RHS,RHS_repeat
k141_2831_1	1121396.KB893090_gene242	1.08e-98	295.0	COG1092@1|root,COG1092@2|Bacteria,1QW1V@1224|Proteobacteria,42Q3P@68525|delta/epsilon subdivisions,2WJXM@28221|Deltaproteobacteria,2MHVR@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Belongs to the methyltransferase superfamily	-	-	2.1.1.173,2.1.1.191,2.1.1.264	ko:K06969,ko:K12297	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
k141_3549_2	345073.VC395_2514	1.16e-126	367.0	COG1589@1|root,COG1589@2|Bacteria,1N0T7@1224|Proteobacteria,1S9FJ@1236|Gammaproteobacteria,1XTAJ@135623|Vibrionales	135623|Vibrionales	D	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly	ftsQ	-	-	ko:K03589	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036	-	-	-	FtsQ,POTRA_1
k141_4924_1	760154.Sulba_1369	6.65e-60	217.0	COG3210@1|root,COG3210@2|Bacteria,1MX2K@1224|Proteobacteria,42MHY@68525|delta/epsilon subdivisions,2YNDP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	U	domain protein	-	-	-	ko:K15125	ko05133,map05133	-	-	-	ko00000,ko00001,ko00536	-	-	-	Fil_haemagg_2,Haemagg_act
k141_235_1	29495.EA26_19035	0.0	1565.0	COG0553@1|root,COG0553@2|Bacteria,1MX6H@1224|Proteobacteria,1RNRZ@1236|Gammaproteobacteria,1XTMU@135623|Vibrionales	135623|Vibrionales	K	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair	rapA	GO:0000166,GO:0003674,GO:0003824,GO:0004386,GO:0005488,GO:0005524,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0018130,GO:0019438,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0097659,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576	-	ko:K03580	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	Helicase_C,RapA_C,SNF2_N
k141_3550_1	644282.Deba_0099	7.72e-55	202.0	COG4773@1|root,COG4773@2|Bacteria,1QTXJ@1224|Proteobacteria,43CM6@68525|delta/epsilon subdivisions	1224|Proteobacteria	P	COG1629 Outer membrane receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
k141_544_1	425104.Ssed_1335	0.000861	45.8	COG1595@1|root,COG1595@2|Bacteria,1N38X@1224|Proteobacteria,1SASQ@1236|Gammaproteobacteria,2Q9NP@267890|Shewanellaceae	1236|Gammaproteobacteria	K	PFAM sigma-70 region 2 domain protein	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
k141_544_2	675815.VOA_002349	3.06e-36	127.0	2DTB0@1|root,33JH6@2|Bacteria,1NPKK@1224|Proteobacteria,1SJBY@1236|Gammaproteobacteria,1XY5Y@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_544_3	1280001.BAOA01000008_gene4088	1.17e-127	370.0	COG0500@1|root,COG2226@2|Bacteria,1MXDY@1224|Proteobacteria,1RMU7@1236|Gammaproteobacteria,1XTTF@135623|Vibrionales	135623|Vibrionales	H	COG0500 SAM-dependent methyltransferases	rrmA	-	2.1.1.187	ko:K00563	-	-	R07233	RC00003	ko00000,ko01000,ko03009	-	-	-	Methyltransf_25,Methyltransf_31
k141_544_4	243277.VC_2001	5.39e-117	344.0	COG0676@1|root,COG0676@2|Bacteria,1Q7VN@1224|Proteobacteria,1RQK0@1236|Gammaproteobacteria,1XSYW@135623|Vibrionales	135623|Vibrionales	G	Belongs to the glucose-6-phosphate 1-epimerase family	-	-	5.1.3.15	ko:K01792	ko00010,ko01100,ko01110,ko01120,ko01130,map00010,map01100,map01110,map01120,map01130	-	R02739	RC00563	ko00000,ko00001,ko01000	-	-	-	Aldose_epim
k141_3551_1	1267580.AF6_2203	3.49e-30	125.0	COG0840@1|root,COG0840@2|Bacteria,1TP5A@1239|Firmicutes,4HCXW@91061|Bacilli,21X42@150247|Anoxybacillus	91061|Bacilli	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal,dCache_1
k141_1224_3	391612.CY0110_05842	1.2e-10	71.2	COG0643@1|root,COG0745@1|root,COG2198@1|root,COG0643@2|Bacteria,COG0745@2|Bacteria,COG2198@2|Bacteria,1G0VR@1117|Cyanobacteria,3KGCU@43988|Cyanothece	1117|Cyanobacteria	T	Histidine Phosphotransfer domain	-	-	-	ko:K06596	ko02020,ko02025,map02020,map02025	M00507	-	-	ko00000,ko00001,ko00002,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt,Response_reg
k141_1224_4	1304885.AUEY01000052_gene1557	4.41e-29	122.0	2DJFZ@1|root,30600@2|Bacteria,1Q9C3@1224|Proteobacteria,4364J@68525|delta/epsilon subdivisions,2X9FR@28221|Deltaproteobacteria,2MPAT@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_4925_2	1304885.AUEY01000041_gene3688	5.94e-252	723.0	COG1032@1|root,COG5011@1|root,COG1032@2|Bacteria,COG5011@2|Bacteria,1MV5G@1224|Proteobacteria,42MPT@68525|delta/epsilon subdivisions,2WJG9@28221|Deltaproteobacteria,2MHW1@213118|Desulfobacterales	28221|Deltaproteobacteria	C	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	DUF2344,Radical_SAM
k141_5244_4	675815.VOA_000357	5.62e-39	130.0	COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,1SCA7@1236|Gammaproteobacteria,1XYBB@135623|Vibrionales	135623|Vibrionales	K	COG1278 Cold shock proteins	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
k141_5244_5	156578.ATW7_12838	2.52e-124	360.0	COG1864@1|root,COG1864@2|Bacteria,1RADP@1224|Proteobacteria,1RZVW@1236|Gammaproteobacteria	1236|Gammaproteobacteria	F	DNA RNA endonuclease G, NUC1	nucA	-	-	ko:K01173	ko04210,map04210	-	-	-	ko00000,ko00001,ko03029	-	-	-	Endonuclease_NS
k141_5244_6	1225184.ALXE01000020_gene2814	1.68e-234	657.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,1RMBQ@1236|Gammaproteobacteria,3VZ5M@53335|Pantoea	1236|Gammaproteobacteria	C	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the reversible oxidation of betaine aldehyde to the corresponding acid	-	-	1.2.99.10	ko:K22445	-	-	-	-	ko00000,ko01000	-	-	-	Aldedh
k141_5244_7	1515746.HR45_15335	5.42e-163	462.0	COG0583@1|root,COG0583@2|Bacteria,1QVFF@1224|Proteobacteria,1RMUA@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
k141_5244_9	637905.SVI_0871	5.52e-257	739.0	COG3291@1|root,COG5297@1|root,COG3291@2|Bacteria,COG5297@2|Bacteria,1R47A@1224|Proteobacteria,1RREU@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	Belongs to the glycosyl hydrolase family 6	cel6A	-	3.2.1.91	ko:K19668	ko00500,ko01100,ko02020,map00500,map01100,map02020	-	R02886,R11308	RC00799	ko00000,ko00001,ko01000	-	GH6	-	CBM_10,CBM_2,Glyco_hydro_6,PKD
k141_5244_10	566466.NOR53_2016	6e-36	150.0	COG2199@1|root,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,1S6MK@1236|Gammaproteobacteria,1J7VI@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Response_reg
k141_1287_15	1227349.C170_29513	1.25e-18	88.2	COG0791@1|root,COG4099@1|root,COG0791@2|Bacteria,COG4099@2|Bacteria,1V3AJ@1239|Firmicutes,4HHP0@91061|Bacilli,26V21@186822|Paenibacillaceae	91061|Bacilli	M	Esterase PHB depolymerase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_2,CHB_HEX_C_1,Esterase,Esterase_phd,Peptidase_S9,SLH
k141_1287_16	55601.VANGNB10_cI1441c	1.82e-194	559.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1SKEV@1236|Gammaproteobacteria,1XUA2@135623|Vibrionales	135623|Vibrionales	NT	methyl-accepting chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal
k141_1287_17	55601.VANGNB10_cI1440c	1.24e-136	390.0	COG0834@1|root,COG0834@2|Bacteria,1RBXC@1224|Proteobacteria,1S31V@1236|Gammaproteobacteria,1XWHX@135623|Vibrionales	135623|Vibrionales	ET	ABC-type amino acid transport signal transduction systems, periplasmic component domain	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
k141_1287_18	579405.Dd703_3133	1.43e-96	288.0	COG0745@1|root,COG0745@2|Bacteria,1MVQT@1224|Proteobacteria,1RNSY@1236|Gammaproteobacteria,2JDGK@204037|Dickeya	1236|Gammaproteobacteria	K	Two component transcriptional regulator, winged helix family	-	-	-	ko:K18144	ko01501,map01501	M00649,M00655	-	-	ko00000,ko00001,ko00002,ko01504,ko02022	-	-	-	Response_reg,Trans_reg_C
k141_1287_19	198628.Dda3937_01472	8.54e-127	377.0	COG0642@1|root,COG2205@2|Bacteria,1PM9S@1224|Proteobacteria,1RR1Y@1236|Gammaproteobacteria,2JCCY@204037|Dickeya	1236|Gammaproteobacteria	T	histidine kinase HAMP region domain protein	baeS	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
k141_1287_20	198628.Dda3937_01473	2.02e-90	284.0	COG0845@1|root,COG0845@2|Bacteria,1PVWV@1224|Proteobacteria,1RMYG@1236|Gammaproteobacteria,2JE01@204037|Dickeya	1236|Gammaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
k141_1287_21	104623.Ser39006_01927	0.0	1228.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,4026I@613|Serratia	1236|Gammaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K18138,ko:K18303,ko:K21134	ko01501,ko01503,map01501,map01503	M00642,M00647,M00699,M00718,M00821	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2,2.A.6.2.17,2.A.6.2.27	-	-	ACR_tran
k141_1287_22	1484157.PSNIH2_13025	1.55e-110	323.0	COG1124@1|root,COG1124@2|Bacteria,1MUGH@1224|Proteobacteria,1RR8V@1236|Gammaproteobacteria,3VY5U@53335|Pantoea	1236|Gammaproteobacteria	EP	ABC transporter	-	-	-	ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran
k141_1287_23	104623.Ser39006_00428	5.17e-120	352.0	COG0444@1|root,COG0444@2|Bacteria,1NTNP@1224|Proteobacteria,1RPAS@1236|Gammaproteobacteria,4021Q@613|Serratia	1236|Gammaproteobacteria	EP	Peptide ABC transporter ATP-binding protein	gsiA_3	-	-	ko:K02031	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran
k141_1287_24	1151116.Q7S_12405	2.03e-142	409.0	COG1173@1|root,COG1173@2|Bacteria,1MW3R@1224|Proteobacteria,1RMMR@1236|Gammaproteobacteria,3FF7D@34037|Rahnella	1236|Gammaproteobacteria	EP	ABC-type dipeptide oligopeptide nickel transport	yddQ	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
k141_1287_25	400668.Mmwyl1_2057	1.11e-184	521.0	COG0601@1|root,COG0601@2|Bacteria,1MU8Z@1224|Proteobacteria,1RNAW@1236|Gammaproteobacteria,1XIRT@135619|Oceanospirillales	135619|Oceanospirillales	EP	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
k141_1287_26	400668.Mmwyl1_2056	5.58e-283	784.0	COG0747@1|root,COG0747@2|Bacteria,1MWR7@1224|Proteobacteria,1RQV4@1236|Gammaproteobacteria,1XJA8@135619|Oceanospirillales	135619|Oceanospirillales	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
k141_1287_28	1523503.JPMY01000003_gene4088	9.16e-114	337.0	COG4188@1|root,COG4188@2|Bacteria,1RJGF@1224|Proteobacteria,1SHKE@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	dienelactone hydrolase	-	-	3.1.1.101	ko:K21104	-	-	R11540	-	ko00000,ko01000	-	-	-	-
k141_1287_29	1268237.G114_04098	9.74e-210	602.0	COG0443@1|root,COG0443@2|Bacteria,1MUR1@1224|Proteobacteria,1RR7P@1236|Gammaproteobacteria,1Y6H2@135624|Aeromonadales	135624|Aeromonadales	O	MreB/Mbl protein	-	-	-	ko:K04045	-	-	-	-	ko00000,ko03110	1.A.33	-	-	HSP70
k141_2003_1	247633.GP2143_16941	1.81e-22	110.0	COG1629@1|root,COG4771@2|Bacteria,1R6MZ@1224|Proteobacteria	1224|Proteobacteria	M	COG1629 Outer membrane receptor proteins, mostly Fe transport	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
k141_2003_2	1121405.dsmv_3166	8.65e-113	351.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MC4@68525|delta/epsilon subdivisions,2WIZU@28221|Deltaproteobacteria,2MJ29@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg,dCache_3
k141_3986_1	617140.AJZE01000076_gene1300	2.45e-180	568.0	COG0419@1|root,COG0419@2|Bacteria,1MVTQ@1224|Proteobacteria,1RQFM@1236|Gammaproteobacteria,1XT7J@135623|Vibrionales	135623|Vibrionales	L	COG0419 ATPase involved in DNA repair	sbcC	GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0006139,GO:0006259,GO:0006260,GO:0006310,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360,GO:1901576	-	ko:K03546	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,AAA_29,SbcCD_C
k141_2004_1	1283300.ATXB01000001_gene1225	4.82e-55	198.0	COG1520@1|root,COG2911@1|root,COG2931@1|root,COG3210@1|root,COG4625@1|root,COG1520@2|Bacteria,COG2911@2|Bacteria,COG2931@2|Bacteria,COG3210@2|Bacteria,COG4625@2|Bacteria,1MU7T@1224|Proteobacteria,1RNK8@1236|Gammaproteobacteria,1XFUS@135618|Methylococcales	135618|Methylococcales	QU	COG2931 RTX toxins and related Ca2 -binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_883_1	1304885.AUEY01000043_gene3627	3.56e-206	642.0	COG2373@1|root,COG2373@2|Bacteria,1MV7J@1224|Proteobacteria,42MJ8@68525|delta/epsilon subdivisions,2WJF3@28221|Deltaproteobacteria,2MJDK@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Alpha-2-Macroglobulin	-	-	-	ko:K06894	-	-	-	-	ko00000	-	-	-	A2M,A2M_N,A2M_N_2,MG1,Thiol-ester_cl
k141_2311_1	1265505.ATUG01000002_gene2577	4.23e-10	63.5	COG5616@1|root,COG5616@2|Bacteria,1RBBE@1224|Proteobacteria,42QR8@68525|delta/epsilon subdivisions,2WN1X@28221|Deltaproteobacteria,2MHSI@213118|Desulfobacterales	28221|Deltaproteobacteria	S	PFAM Curli production assembly transport component CsgG	-	-	-	-	-	-	-	-	-	-	-	-	CsgG,VCBS
k141_2311_2	1304885.AUEY01000016_gene3071	9.83e-20	90.5	2DDGH@1|root,32U1F@2|Bacteria,1N0N4@1224|Proteobacteria,42TTB@68525|delta/epsilon subdivisions,2WQVT@28221|Deltaproteobacteria,2MKKK@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase
k141_4702_1	909943.HIMB100_00009080	4.43e-56	186.0	COG1186@1|root,COG1186@2|Bacteria,1MUAW@1224|Proteobacteria,2TR9V@28211|Alphaproteobacteria,4BP5Y@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	-	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
k141_4702_2	429009.Adeg_0623	7.25e-71	219.0	COG2206@1|root,COG2206@2|Bacteria,1W46Q@1239|Firmicutes,256AM@186801|Clostridia	186801|Clostridia	T	PFAM metal-dependent phosphohydrolase, HD sub domain	-	-	-	ko:K06950	-	-	-	-	ko00000	-	-	-	HD
k141_4702_3	140626.JHWB01000009_gene1420	3.49e-19	89.4	COG0351@1|root,COG0352@1|root,COG0351@2|Bacteria,COG0352@2|Bacteria,1TQ4A@1239|Firmicutes,2483H@186801|Clostridia	186801|Clostridia	H	Phosphomethylpyrimidine kinase	thiD	-	2.7.1.49,2.7.4.7	ko:K00941	ko00730,ko01100,map00730,map01100	M00127	R03471,R04509	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Phos_pyr_kin
k141_3269_1	999541.bgla_1g06540	8.39e-41	149.0	COG0345@1|root,COG0345@2|Bacteria,1R5J1@1224|Proteobacteria,2VJD1@28216|Betaproteobacteria,1JZPH@119060|Burkholderiaceae	28216|Betaproteobacteria	E	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline	proC	-	1.5.1.2	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	M00015	R01248,R01251,R03291,R03293	RC00054,RC00083	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_oxidored,P5CR_dimer
k141_3269_2	1316927.ATKI01000065_gene2021	7.83e-13	80.9	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,1YMNV@136843|Pseudomonas fluorescens group	1236|Gammaproteobacteria	NT	methyl-accepting chemotaxis protein	VPA0491	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,HBM,MCPsignal
k141_884_2	768671.ThimaDRAFT_0305	1.14e-37	137.0	COG3177@1|root,COG3177@2|Bacteria,1MWAU@1224|Proteobacteria,1RRHZ@1236|Gammaproteobacteria,1WW8V@135613|Chromatiales	135613|Chromatiales	S	Fic/DOC family	-	-	-	-	-	-	-	-	-	-	-	-	Fic
k141_2312_1	933262.AXAM01000087_gene3286	2.99e-31	115.0	2DMJU@1|root,32S1Y@2|Bacteria,1N5H8@1224|Proteobacteria,42TGX@68525|delta/epsilon subdivisions,2WQNI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Cytochrome C and Quinol oxidase polypeptide I	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_2312_2	1121396.KB893058_gene2572	9.5e-98	303.0	COG1629@1|root,COG4771@2|Bacteria,1MUC1@1224|Proteobacteria,42NGM@68525|delta/epsilon subdivisions,2WKKR@28221|Deltaproteobacteria,2MMH5@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Outer membrane protein beta-barrel family	-	-	-	ko:K16089	-	-	-	-	ko00000,ko02000	1.B.14.1,1.B.14.10	-	-	Plug,TonB_dep_Rec
k141_4703_1	1121403.AUCV01000124_gene2974	1.52e-62	207.0	COG2433@1|root,COG2433@2|Bacteria,1RE5Q@1224|Proteobacteria,42WSA@68525|delta/epsilon subdivisions,2WRPQ@28221|Deltaproteobacteria,2MMJ3@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Transposase IS66 family	-	-	-	ko:K07484	-	-	-	-	ko00000	-	-	-	DDE_Tnp_IS66,zf-IS66
k141_2005_1	29495.EA26_17115	8.2e-129	377.0	COG1344@1|root,COG1344@2|Bacteria,1MV1N@1224|Proteobacteria,1RN0Y@1236|Gammaproteobacteria,1XSDK@135623|Vibrionales	135623|Vibrionales	N	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella	flaD	GO:0005575,GO:0005576,GO:0005623,GO:0009288,GO:0042995,GO:0043226,GO:0043228,GO:0044464	-	ko:K02406	ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flagellin_C,Flagellin_IN,Flagellin_N
k141_2313_1	1232437.KL661985_gene3573	1.05e-55	179.0	COG1633@1|root,COG1633@2|Bacteria,1N36M@1224|Proteobacteria,42UVX@68525|delta/epsilon subdivisions,2WQ53@28221|Deltaproteobacteria,2MMYP@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Rubrerythrin	-	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
k141_4976_1	386415.NT01CX_0672	9.94e-81	249.0	COG2013@1|root,COG2013@2|Bacteria,1TSVH@1239|Firmicutes,24DQR@186801|Clostridia,36R6E@31979|Clostridiaceae	186801|Clostridia	S	Mitochondrial biogenesis AIM24	-	-	-	-	-	-	-	-	-	-	-	-	AIM24
k141_4976_2	929506.CbC4_2400	5.75e-73	228.0	COG2310@1|root,COG2310@2|Bacteria,1TNZQ@1239|Firmicutes,24A3Y@186801|Clostridia,36GMM@31979|Clostridiaceae	186801|Clostridia	T	resistance protein	terD_2	-	-	ko:K05795	-	-	-	-	ko00000	-	-	-	TerD
k141_4976_4	929506.CbC4_0126	2.94e-198	572.0	COG0513@1|root,COG0513@2|Bacteria,1TPAP@1239|Firmicutes,247IT@186801|Clostridia,36DXA@31979|Clostridiaceae	186801|Clostridia	L	Belongs to the DEAD box helicase family	cshA	-	3.6.4.13	ko:K05592	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	DEAD,DbpA,Helicase_C
k141_4976_6	1121447.JONL01000001_gene319	5.53e-07	53.1	COG2703@1|root,COG2703@2|Bacteria,1PG7G@1224|Proteobacteria,4360D@68525|delta/epsilon subdivisions,2X0HW@28221|Deltaproteobacteria,2MCDB@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	Hemerythrin HHE cation binding domain	-	-	-	ko:K07216	-	-	-	-	ko00000	-	-	-	Hemerythrin
k141_4976_8	1423815.BACR01000038_gene1913	4.09e-06	53.5	COG0789@1|root,COG0789@2|Bacteria,1V6C0@1239|Firmicutes,4HI5N@91061|Bacilli,3F6NG@33958|Lactobacillaceae	91061|Bacilli	K	helix_turn_helix, mercury resistance	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
k141_4976_10	622312.ROSEINA2194_04451	9.75e-07	51.2	COG1595@1|root,COG1595@2|Bacteria,1VCZT@1239|Firmicutes,25BT1@186801|Clostridia	186801|Clostridia	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
k141_4976_14	1410653.JHVC01000007_gene617	8e-51	166.0	2CFUA@1|root,32S2G@2|Bacteria,1V63K@1239|Firmicutes,24N34@186801|Clostridia,36K8A@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_4704_1	1116375.VEJY3_20481	3.82e-44	155.0	COG1115@1|root,COG1115@2|Bacteria,1MUI3@1224|Proteobacteria,1RMNF@1236|Gammaproteobacteria,1XZXD@135623|Vibrionales	135623|Vibrionales	E	Sodium:alanine symporter family	-	-	-	ko:K03310	-	-	-	-	ko00000	2.A.25	-	-	Na_Ala_symp
k141_2887_1	1280001.BAOA01000007_gene3802	1.7e-273	758.0	COG3037@1|root,COG3414@1|root,COG3037@2|Bacteria,COG3414@2|Bacteria,1MWNR@1224|Proteobacteria,1RP9S@1236|Gammaproteobacteria,1Y2KU@135623|Vibrionales	135623|Vibrionales	G	PTS system sugar-specific permease component	ulaA	-	2.7.1.194	ko:K02822,ko:K03475	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	M00283,M00550	R07671	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.7.1	-	-	EIIC-GAT,PTS_IIB
k141_2887_4	545696.HOLDEFILI_00983	1.79e-136	398.0	28IPH@1|root,2Z8PG@2|Bacteria,1TREB@1239|Firmicutes,3VP7D@526524|Erysipelotrichia	526524|Erysipelotrichia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_2887_5	675813.VIB_002245	6.39e-140	401.0	COG0561@1|root,COG0561@2|Bacteria,1PGMI@1224|Proteobacteria,1RPYI@1236|Gammaproteobacteria,1XV8T@135623|Vibrionales	135623|Vibrionales	S	of the HAD superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
k141_3692_2	1116375.VEJY3_22326	5.93e-188	530.0	COG0787@1|root,COG0787@2|Bacteria,1MV0Q@1224|Proteobacteria,1RM8U@1236|Gammaproteobacteria,1XSJM@135623|Vibrionales	135623|Vibrionales	M	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	-	-	5.1.1.1	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N
k141_3692_3	1219080.VEZ01S_22_00070	4.97e-61	190.0	2B2JB@1|root,31V4J@2|Bacteria,1N4EU@1224|Proteobacteria,1S6JW@1236|Gammaproteobacteria,1XXC5@135623|Vibrionales	135623|Vibrionales	S	Protein of unknown function (DUF2750)	VV1382	-	-	-	-	-	-	-	-	-	-	-	DUF2750
k141_1289_1	203119.Cthe_0325	4.99e-212	612.0	COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,1TQ38@1239|Firmicutes,2484Z@186801|Clostridia,3WH2R@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source	nadE	-	6.3.5.1	ko:K01950	ko00760,ko01100,map00760,map01100	M00115	R00257	RC00010,RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase,NAD_synthase
k141_1289_2	1238450.VIBNISOn1_1510002	4.06e-09	54.3	COG4115@1|root,COG4115@2|Bacteria,1MZBP@1224|Proteobacteria,1S99Z@1236|Gammaproteobacteria,1XY05@135623|Vibrionales	135623|Vibrionales	S	YoeB-like toxin of bacterial type II toxin-antitoxin system	yoeB	-	-	ko:K19158	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	YoeB_toxin
k141_1289_3	933262.AXAM01000055_gene1268	1.14e-33	117.0	COG2161@1|root,COG2161@2|Bacteria,1PT51@1224|Proteobacteria,42WVC@68525|delta/epsilon subdivisions,2WTHQ@28221|Deltaproteobacteria,2MMF9@213118|Desulfobacterales	28221|Deltaproteobacteria	D	Antitoxin component of a toxin-antitoxin (TA) module	-	-	-	ko:K19159	-	-	-	-	ko00000,ko02048	-	-	-	PhdYeFM_antitox
k141_3270_3	189425.PGRAT_24935	2.59e-59	198.0	COG0675@1|root,COG0675@2|Bacteria,1TT4J@1239|Firmicutes,4HEKB@91061|Bacilli,26UMB@186822|Paenibacillaceae	91061|Bacilli	L	Putative transposase DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	OrfB_IS605,OrfB_Zn_ribbon
k141_3990_1	1282362.AEAC466_17580	2.09e-118	372.0	COG0840@1|root,COG3287@1|root,COG0840@2|Bacteria,COG3287@2|Bacteria,1MVUZ@1224|Proteobacteria,2TRRI@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	GfdT protein	-	-	-	-	-	-	-	-	-	-	-	-	FIST,FIST_C,MCPsignal
k141_885_2	675815.VOA_001964	1.94e-119	371.0	COG3673@1|root,COG3673@2|Bacteria,1QV8K@1224|Proteobacteria,1T29Z@1236|Gammaproteobacteria,1XV7E@135623|Vibrionales	135623|Vibrionales	S	Uncharacterized alpha/beta hydrolase domain (DUF2235)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2235
k141_4706_1	1307761.L21SP2_3284	2.86e-81	260.0	COG4974@1|root,COG4974@2|Bacteria,2J7KY@203691|Spirochaetes	203691|Spirochaetes	L	Transposase IS66 family	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS66,DDE_Tnp_IS66_C,LZ_Tnp_IS66,zf-IS66
k141_4707_1	944479.JQLX01000011_gene782	2.09e-18	85.9	COG1538@1|root,COG1538@2|Bacteria,1PTZ6@1224|Proteobacteria,42RK2@68525|delta/epsilon subdivisions,2WNMB@28221|Deltaproteobacteria,2M70F@213113|Desulfurellales	28221|Deltaproteobacteria	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
k141_2315_1	177437.HRM2_46940	8.12e-11	65.9	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,4301W@68525|delta/epsilon subdivisions,2WWPV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	SMART chemotaxis sensory transducer	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal,PAS_4
k141_2006_1	1504672.669783588	1.25e-54	215.0	COG2931@1|root,COG3210@1|root,COG4625@1|root,COG2931@2|Bacteria,COG3210@2|Bacteria,COG4625@2|Bacteria,1MU7T@1224|Proteobacteria	1224|Proteobacteria	Q	COG2931, RTX toxins and related Ca2 -binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	DUF4347,DUF5122,HemolysinCabind,Lactonase,Laminin_G_3,Peptidase_M10_C,W_rich_C
k141_4709_1	498211.CJA_2519	1.53e-34	127.0	COG0760@1|root,COG0760@2|Bacteria,1PK21@1224|Proteobacteria,1S180@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	PPIC-type PPIASE domain	-	-	5.2.1.8	ko:K03769	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase_3
k141_4709_2	1117319.PSPO_20371	1.03e-20	96.7	COG0760@1|root,COG0760@2|Bacteria,1RFHH@1224|Proteobacteria,1S4J2@1236|Gammaproteobacteria,2Q2M0@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	O	PPIC-type PPIASE domain	-	-	-	-	-	-	-	-	-	-	-	-	Rotamase_2
k141_1290_1	1304885.AUEY01000022_gene3412	2.35e-92	277.0	COG0110@1|root,COG0110@2|Bacteria,1N6SQ@1224|Proteobacteria,42PE2@68525|delta/epsilon subdivisions,2WKVK@28221|Deltaproteobacteria,2MJ81@213118|Desulfobacterales	28221|Deltaproteobacteria	S	PFAM transferase hexapeptide repeat containing protein	-	-	2.3.1.79	ko:K00661	-	-	-	-	ko00000,ko01000	-	-	-	Hexapep,Hexapep_2
k141_1290_2	1265505.ATUG01000002_gene1535	3.53e-138	403.0	COG3387@1|root,COG3387@2|Bacteria,1NB01@1224|Proteobacteria,42N48@68525|delta/epsilon subdivisions,2WJRY@28221|Deltaproteobacteria,2MHXM@213118|Desulfobacterales	28221|Deltaproteobacteria	G	PFAM Glycoside hydrolase 15-related	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_3272_1	207559.Dde_3039	4.87e-75	246.0	COG1882@1|root,COG1882@2|Bacteria,1MWBF@1224|Proteobacteria,42M5J@68525|delta/epsilon subdivisions,2WJAK@28221|Deltaproteobacteria,2M9FS@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	Glycine radical	cutC	GO:0001505,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006576,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009308,GO:0009310,GO:0009987,GO:0016829,GO:0016840,GO:0019695,GO:0033265,GO:0034641,GO:0042133,GO:0042135,GO:0042165,GO:0042402,GO:0042426,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0044106,GO:0044237,GO:0044248,GO:0046983,GO:0065007,GO:0065008,GO:0070405,GO:0071704,GO:0097164,GO:1901564,GO:1901565,GO:1901575	4.3.99.4	ko:K20038	-	-	-	-	ko00000,ko01000	-	-	-	Gly_radical,PFL-like
k141_3272_2	1333507.AUTQ01000128_gene1108	6.83e-15	71.6	2E6H5@1|root,3314C@2|Bacteria,1PVV7@1224|Proteobacteria,1SF4B@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF2809)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2809
k141_887_1	1265505.ATUG01000001_gene4348	1.28e-25	99.0	COG0023@1|root,COG0023@2|Bacteria,1MZ8T@1224|Proteobacteria,42TW6@68525|delta/epsilon subdivisions,2WQNT@28221|Deltaproteobacteria,2MKRE@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Translation initiation factor SUI1	yciH	-	-	ko:K03113	ko03013,map03013	-	-	-	ko00000,ko00001,ko03012	-	-	-	SUI1
k141_887_2	411465.PEPMIC_00324	1.05e-161	462.0	COG1087@1|root,COG1087@2|Bacteria,1TQ7N@1239|Firmicutes,247M9@186801|Clostridia,22GHA@1570339|Peptoniphilaceae	186801|Clostridia	M	UDP-glucose 4-epimerase	galE	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
k141_4977_1	458817.Shal_2013	9.7e-67	208.0	COG3822@1|root,COG3822@2|Bacteria,1RCP1@1224|Proteobacteria,1S1ZG@1236|Gammaproteobacteria,2QDM1@267890|Shewanellaceae	1236|Gammaproteobacteria	S	D-lyxose isomerase	Z012_00995	-	5.3.1.15	ko:K09988	ko00040,map00040	-	R01898	RC00516	ko00000,ko00001,ko01000	-	-	-	Lyx_isomer
k141_4977_2	71421.HI_1113	2.33e-205	586.0	COG1070@1|root,COG1070@2|Bacteria,1MW4A@1224|Proteobacteria,1RR7X@1236|Gammaproteobacteria,1Y6XS@135625|Pasteurellales	135625|Pasteurellales	G	Xylulose kinase	xylB	-	2.7.1.17	ko:K00854	ko00040,ko01100,map00040,map01100	M00014	R01639	RC00002,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	-	FGGY_C,FGGY_N
k141_4977_3	598467.BrE312_1464	1.36e-148	427.0	COG1172@1|root,COG1172@2|Bacteria,1R606@1224|Proteobacteria,1RYGK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	U	transport system permease	-	-	-	ko:K10440	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	BPD_transp_2
k141_3475_2	439235.Dalk_4809	1.94e-20	85.9	COG1872@1|root,COG1872@2|Bacteria,1MZ4E@1224|Proteobacteria,42VE5@68525|delta/epsilon subdivisions,2WR8T@28221|Deltaproteobacteria,2MM5T@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Belongs to the UPF0235 family	-	-	-	ko:K09131	-	-	-	-	ko00000	-	-	-	DUF167
k141_3776_1	550540.Fbal_3387	4.01e-33	127.0	COG0604@1|root,COG0604@2|Bacteria,1MV3W@1224|Proteobacteria,1RMHG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases	yhdH	GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0016627,GO:0016628,GO:0043957,GO:0055114	-	ko:K19745	ko00640,ko01100,map00640,map01100	-	R00919	RC00095	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
k141_1419_1	338963.Pcar_1580	1.51e-91	283.0	COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,42MFH@68525|delta/epsilon subdivisions,2WIRW@28221|Deltaproteobacteria,43TYZ@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	PFAM sigma-54 factor interaction domain-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,PAS_4,PAS_9,Sigma54_activat
k141_2408_1	1348635.BBJY01000003_gene3864	6.4e-33	134.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RSAR@1236|Gammaproteobacteria,1Y0DG@135623|Vibrionales	135623|Vibrionales	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
k141_2408_2	1219065.VPR01S_06_01850	3.66e-308	848.0	COG1292@1|root,COG1292@2|Bacteria,1MV0K@1224|Proteobacteria,1RP3E@1236|Gammaproteobacteria,1XTJH@135623|Vibrionales	135623|Vibrionales	M	Belongs to the BCCT transporter (TC 2.A.15) family	-	-	-	ko:K03451	-	-	-	-	ko00000	2.A.15	-	-	BCCT
k141_3476_1	679190.HMPREF0650_1843	2.69e-10	61.2	COG0632@1|root,COG0632@2|Bacteria,4NF4E@976|Bacteroidetes,2FNA8@200643|Bacteroidia	976|Bacteroidetes	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB	ruvA	-	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_C,RuvA_N
k141_3476_2	1517682.HW49_04025	5.87e-32	127.0	COG1747@1|root,COG1747@2|Bacteria,4NEB8@976|Bacteroidetes,2FXZH@200643|Bacteroidia,22W8T@171551|Porphyromonadaceae	976|Bacteroidetes	S	Gliding motility protein	sprA	-	-	-	-	-	-	-	-	-	-	-	SprA_N
k141_5129_1	1121403.AUCV01000033_gene3674	9.25e-132	381.0	COG0702@1|root,COG0702@2|Bacteria,1Q438@1224|Proteobacteria,439WM@68525|delta/epsilon subdivisions,2X29K@28221|Deltaproteobacteria,2MPBK@213118|Desulfobacterales	28221|Deltaproteobacteria	GM	NmrA-like family	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10
k141_5129_2	29495.EA26_14250	9.46e-23	93.6	COG3177@1|root,COG3177@2|Bacteria,1MWA8@1224|Proteobacteria,1RRFR@1236|Gammaproteobacteria,1XV0W@135623|Vibrionales	135623|Vibrionales	S	Fic/DOC family	-	-	-	-	-	-	-	-	-	-	-	-	Fic
k141_5129_3	1504981.KO116_1995	4.36e-28	107.0	COG3177@1|root,COG3177@2|Bacteria,1MWA8@1224|Proteobacteria,1RRFR@1236|Gammaproteobacteria,1XH2K@135619|Oceanospirillales	135619|Oceanospirillales	S	Fic/DOC family	-	-	-	-	-	-	-	-	-	-	-	-	Fic
k141_1420_1	865937.Gilli_3023	0.000463	48.1	COG2204@1|root,COG2204@2|Bacteria,4NE89@976|Bacteroidetes,1HWRZ@117743|Flavobacteriia,2P5E3@244698|Gillisia	976|Bacteroidetes	T	Sigma-54 interaction domain	ntrX	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
k141_741_1	1121422.AUMW01000006_gene705	2.56e-52	181.0	COG2204@1|root,COG2204@2|Bacteria,1VSKG@1239|Firmicutes,24ZP4@186801|Clostridia	186801|Clostridia	T	Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,PEP_hydrolase,Response_reg,Sigma54_activat
k141_741_3	941449.dsx2_1626	1.57e-15	74.7	COG0730@1|root,COG0730@2|Bacteria,1MWX2@1224|Proteobacteria,42R15@68525|delta/epsilon subdivisions,2WJR6@28221|Deltaproteobacteria,2MGF0@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
k141_3105_1	675814.VIC_004624	7.43e-60	192.0	COG2908@1|root,COG2908@2|Bacteria,1N3U7@1224|Proteobacteria,1RP1X@1236|Gammaproteobacteria,1XSQ8@135623|Vibrionales	135623|Vibrionales	S	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxH	-	3.6.1.54	ko:K03269	ko00540,ko01100,map00540,map01100	M00060	R04549	RC00002	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Metallophos,Metallophos_2
k141_3105_2	945550.VISI1226_22827	1.17e-109	316.0	COG0652@1|root,COG0652@2|Bacteria,1R9ZQ@1224|Proteobacteria,1S222@1236|Gammaproteobacteria,1XVAN@135623|Vibrionales	135623|Vibrionales	G	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	ppiB	-	5.2.1.8	ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Pro_isomerase
k141_3105_3	1238450.VIBNISOn1_50022	1.84e-300	823.0	COG0215@1|root,COG0215@2|Bacteria,1MV8H@1224|Proteobacteria,1RP5K@1236|Gammaproteobacteria,1XTZJ@135623|Vibrionales	135623|Vibrionales	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e,tRNA-synt_1g
k141_3105_4	1348635.BBJY01000013_gene981	8.28e-103	299.0	COG0817@1|root,COG0817@2|Bacteria,1MUJI@1224|Proteobacteria,1RQPJ@1236|Gammaproteobacteria,1XT73@135623|Vibrionales	135623|Vibrionales	L	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group	ruvC	GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576	3.1.22.4	ko:K01159	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvC
k141_3105_5	1517681.HW45_23865	1.52e-107	314.0	COG0632@1|root,COG0632@2|Bacteria,1MWJR@1224|Proteobacteria,1RMET@1236|Gammaproteobacteria,1XSGY@135623|Vibrionales	135623|Vibrionales	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB	ruvA	GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0006139,GO:0006259,GO:0006310,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009378,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0032392,GO:0032508,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_C,RuvA_N
k141_4467_1	1408422.JHYF01000004_gene1456	1.2e-26	102.0	COG0416@1|root,COG0416@2|Bacteria,1TPY8@1239|Firmicutes,248BX@186801|Clostridia,36EUZ@31979|Clostridiaceae	186801|Clostridia	I	PFAM fatty acid synthesis plsX protein	grdD	-	1.21.4.2,1.21.4.3,1.21.4.4	ko:K21576	-	-	-	-	ko00000,ko01000	-	-	-	FA_synthesis
k141_4467_2	1286171.EAL2_c02920	4.36e-233	655.0	COG1292@1|root,COG1292@2|Bacteria,1TRS6@1239|Firmicutes,2482K@186801|Clostridia,25V4W@186806|Eubacteriaceae	186801|Clostridia	U	BCCT, betaine/carnitine/choline family transporter	opuD	-	-	ko:K05020	-	-	-	-	ko00000,ko02000	2.A.15.1.1,2.A.15.1.11	-	-	BCCT
k141_4467_3	1123009.AUID01000013_gene1733	7.17e-157	447.0	COG0492@1|root,COG0492@2|Bacteria,1TNZS@1239|Firmicutes,2491M@186801|Clostridia,26861@186813|unclassified Clostridiales	186801|Clostridia	C	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family	trxB	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
k141_4467_4	929506.CbC4_2389	5.36e-70	223.0	COG0796@1|root,COG0796@2|Bacteria,1TPPR@1239|Firmicutes,249MB@186801|Clostridia,36DHC@31979|Clostridiaceae	186801|Clostridia	M	Provides the (R)-glutamate required for cell wall biosynthesis	murI	-	5.1.1.3	ko:K01776	ko00471,ko01100,map00471,map01100	-	R00260	RC00302	ko00000,ko00001,ko01000,ko01011	-	-	-	Asp_Glu_race
k141_4800_1	1121405.dsmv_0459	2.84e-48	170.0	COG3031@1|root,COG3031@2|Bacteria,1PUWN@1224|Proteobacteria,42T73@68525|delta/epsilon subdivisions,2WPQU@28221|Deltaproteobacteria,2MK5Q@213118|Desulfobacterales	28221|Deltaproteobacteria	U	General secretion pathway protein C	gspC	-	-	ko:K02452	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	PDZ_2,T2SSC
k141_4800_2	1304885.AUEY01000027_gene2375	4.94e-184	546.0	COG1450@1|root,COG1450@2|Bacteria,1MUUA@1224|Proteobacteria,42M9I@68525|delta/epsilon subdivisions,2WK1H@28221|Deltaproteobacteria,2MIEH@213118|Desulfobacterales	28221|Deltaproteobacteria	NU	type II and III secretion system protein	gspD	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	Secretin,Secretin_N
k141_4800_3	177437.HRM2_11300	1.34e-17	87.8	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,42M51@68525|delta/epsilon subdivisions,2WIPP@28221|Deltaproteobacteria,2MHPE@213118|Desulfobacterales	28221|Deltaproteobacteria	NU	type II secretion system protein E	gspE	-	-	ko:K02454	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSE,T2SSE_N
k141_97_1	316275.VSAL_II0608	9.69e-26	100.0	COG1057@1|root,COG1057@2|Bacteria,1N1IS@1224|Proteobacteria,1SA2H@1236|Gammaproteobacteria,1XWZ4@135623|Vibrionales	135623|Vibrionales	H	adenylyltransferase	nadD	-	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
k141_97_2	1348635.BBJY01000001_gene2684	1.18e-242	682.0	COG0784@1|root,COG3437@1|root,COG0784@2|Bacteria,COG3437@2|Bacteria,1NC9X@1224|Proteobacteria,1T1YW@1236|Gammaproteobacteria,1Y337@135623|Vibrionales	135623|Vibrionales	T	COG3437 Response regulator containing a CheY-like receiver domain and an HD-GYP domain	-	GO:0000156,GO:0000160,GO:0003674,GO:0003824,GO:0004112,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008081,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009187,GO:0009214,GO:0009987,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0023052,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035556,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055086,GO:0060089,GO:0065007,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576	-	-	-	-	-	-	-	-	-	-	DUF3369,HD,HD_5,Response_reg
k141_97_3	55601.VANGNB10_cII0209c	5.19e-223	643.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,1RN52@1236|Gammaproteobacteria,1XTD4@135623|Vibrionales	135623|Vibrionales	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE5,HATPase_c
k141_97_4	558152.IQ37_07910	1.36e-47	155.0	2C9B9@1|root,32RP0@2|Bacteria,4NSK0@976|Bacteroidetes,1I3XD@117743|Flavobacteriia,3ZS8X@59732|Chryseobacterium	976|Bacteroidetes	S	type III effector	-	-	-	-	-	-	-	-	-	-	-	-	HopJ
k141_1421_1	1028803.GG9_0327	2.96e-35	132.0	COG1793@1|root,COG1793@2|Bacteria,1MUW3@1224|Proteobacteria,1S2JP@1236|Gammaproteobacteria,1Y7DE@135625|Pasteurellales	135625|Pasteurellales	L	Protein involved in ATP binding, DNA ligase (ATP) activity, DNA ligase activity, DNA ligation involved in DNA repair, DNA recombination and DNA repair	-	GO:0003674,GO:0003824,GO:0003909,GO:0003910,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006266,GO:0006271,GO:0006273,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016874,GO:0016886,GO:0022616,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360,GO:1901576	6.5.1.1,6.5.1.6,6.5.1.7	ko:K10747	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00381,R00382,R10822,R10823	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	DNA_ligase_A_M,DNA_ligase_OB_2
k141_4468_1	177437.HRM2_25640	9.72e-44	149.0	COG0670@1|root,COG0670@2|Bacteria,1MU69@1224|Proteobacteria,42MWD@68525|delta/epsilon subdivisions,2WMG9@28221|Deltaproteobacteria,2MJCA@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Belongs to the BI1 family	ybhL	-	-	ko:K06890,ko:K19416	-	M00742	-	-	ko00000,ko00002,ko02000	1.A.14.2.1	-	-	Bax1-I
k141_4468_2	1229831.M832_05620	2.75e-13	70.9	COG1109@1|root,COG1109@2|Bacteria,2JFS2@204428|Chlamydiae	204428|Chlamydiae	G	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate	glmM	-	5.4.2.10	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	-	R02060	RC00408	ko00000,ko00001,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
k141_2093_3	29495.EA26_04440	7.19e-314	858.0	COG0621@1|root,COG0621@2|Bacteria,1MURS@1224|Proteobacteria,1RMD8@1236|Gammaproteobacteria,1XSQ1@135623|Vibrionales	135623|Vibrionales	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
k141_2093_4	617140.AJZE01000057_gene2121	6.1e-155	447.0	COG0654@1|root,COG0654@2|Bacteria,1MU6I@1224|Proteobacteria,1RND5@1236|Gammaproteobacteria,1XU6J@135623|Vibrionales	135623|Vibrionales	CH	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	ubiF	-	-	ko:K03184	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R06146,R08775	RC01254	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,FAD_binding_3,SE
k141_445_1	1198452.Jab_1c22310	1.25e-39	163.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,47606@75682|Oxalobacteraceae	28216|Betaproteobacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF,PAS_3,PAS_8,PAS_9,Response_reg
k141_445_2	237609.PSAKL28_03470	1.86e-45	177.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	NT	chemotaxis, protein	VPA0491	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal
k141_2094_1	431943.CKL_0410	6.83e-60	187.0	COG1878@1|root,COG1878@2|Bacteria,1V2DJ@1239|Firmicutes,24HUC@186801|Clostridia,36J7J@31979|Clostridiaceae	186801|Clostridia	S	Putative cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Cyclase
k141_446_1	385682.AFSL01000065_gene1679	3.3e-124	362.0	COG0057@1|root,COG0057@2|Bacteria,4NEMF@976|Bacteroidetes,2FMT7@200643|Bacteroidia,3XIPN@558415|Marinilabiliaceae	976|Bacteroidetes	G	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain	gap	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
k141_1774_1	243277.VC_2548	3.28e-53	186.0	COG0729@1|root,COG0729@2|Bacteria,1MUKM@1224|Proteobacteria,1RNQ3@1236|Gammaproteobacteria,1XV1N@135623|Vibrionales	135623|Vibrionales	M	COG0729 Outer membrane protein	ytfM	-	-	ko:K07278	-	-	-	-	ko00000,ko02000	1.B.33.2.4	-	-	Bac_surface_Ag,POTRA,POTRA_TamA_1
k141_1774_2	675806.VII_001321	1.84e-113	329.0	COG0225@1|root,COG0225@2|Bacteria,1MVUS@1224|Proteobacteria,1RNWU@1236|Gammaproteobacteria,1XU05@135623|Vibrionales	135623|Vibrionales	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	GO:0003674,GO:0003824,GO:0006807,GO:0008113,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016667,GO:0016671,GO:0019538,GO:0030091,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0055114,GO:0071704,GO:1901564	1.8.4.11	ko:K07304	-	-	-	-	ko00000,ko01000	-	-	-	PMSR
k141_1774_4	675813.VIB_000579	7.19e-25	102.0	COG0803@1|root,COG0803@2|Bacteria,1QUFM@1224|Proteobacteria,1T1XA@1236|Gammaproteobacteria,1XX4X@135623|Vibrionales	135623|Vibrionales	P	Protein of unknown function (DUF2796)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2796
k141_3124_1	1121324.CLIT_24c01020	1.24e-146	425.0	COG1623@1|root,COG1623@2|Bacteria,1TQD8@1239|Firmicutes,247J4@186801|Clostridia,25QSP@186804|Peptostreptococcaceae	186801|Clostridia	L	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation	disA	-	2.7.7.85	ko:K07067	-	-	-	-	ko00000,ko01000	-	-	-	DisA-linker,DisA_N,HHH,HHH_2
k141_3124_2	1476973.JMMB01000007_gene184	7.94e-200	568.0	COG1066@1|root,COG1066@2|Bacteria,1TQ7Y@1239|Firmicutes,247TA@186801|Clostridia,25QSV@186804|Peptostreptococcaceae	186801|Clostridia	O	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function	radA	-	-	ko:K04485	-	-	-	-	ko00000,ko03400	-	-	-	AAA_25,ATPase,ChlI,Lon_C
k141_134_1	55601.VANGNB10_cI1945c	3.98e-27	102.0	2AWMQ@1|root,31NIF@2|Bacteria,1QK94@1224|Proteobacteria,1TICJ@1236|Gammaproteobacteria,1XYVG@135623|Vibrionales	135623|Vibrionales	-	-	flaI	-	-	ko:K06604	-	-	-	-	ko00000	-	-	-	-
k141_134_2	675815.VOA_002480	1.03e-285	803.0	COG1345@1|root,COG1345@2|Bacteria,1MUVP@1224|Proteobacteria,1RS2S@1236|Gammaproteobacteria,1XU55@135623|Vibrionales	135623|Vibrionales	N	morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end	fliD	GO:0001539,GO:0003674,GO:0005198,GO:0005575,GO:0005576,GO:0005623,GO:0006928,GO:0008150,GO:0009288,GO:0009420,GO:0009421,GO:0009424,GO:0009987,GO:0040011,GO:0042995,GO:0043226,GO:0043228,GO:0044422,GO:0044461,GO:0044463,GO:0044464,GO:0048870,GO:0051179,GO:0051674,GO:0071973,GO:0097588	-	ko:K02407	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flagellin_IN,FliD_C,FliD_N
k141_134_3	675815.VOA_002481	1.6e-48	160.0	COG1334@1|root,COG1334@2|Bacteria,1NH9T@1224|Proteobacteria,1SH7I@1236|Gammaproteobacteria,1XX73@135623|Vibrionales	135623|Vibrionales	N	flagellar protein FlaG	flaG	-	-	ko:K06603	-	-	-	-	ko00000,ko02035	-	-	-	FlaG
k141_447_1	1304885.AUEY01000004_gene1020	4.35e-143	414.0	COG0372@1|root,COG0372@2|Bacteria,1MUKX@1224|Proteobacteria,42N8U@68525|delta/epsilon subdivisions,2WJAN@28221|Deltaproteobacteria,2MIT8@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Belongs to the citrate synthase family	gltA	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
k141_2095_2	672.VV93_v1c21290	2.09e-14	73.6	COG3170@1|root,COG3170@2|Bacteria,1MXV7@1224|Proteobacteria,1RMM5@1236|Gammaproteobacteria,1XUV6@135623|Vibrionales	135623|Vibrionales	NU	COG3170 Tfp pilus assembly protein FimV	-	-	-	ko:K08086	-	-	-	-	ko00000	-	-	-	-
k141_1064_1	96561.Dole_1660	3.98e-207	600.0	COG0480@1|root,COG0480@2|Bacteria,1R0V4@1224|Proteobacteria,42M1F@68525|delta/epsilon subdivisions,2WIYM@28221|Deltaproteobacteria,2MHPT@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Elongation factor Tu domain 2	fusA-1	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
k141_1064_2	1232437.KL661988_gene185	1.23e-09	58.5	COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,42MQI@68525|delta/epsilon subdivisions,2WN1S@28221|Deltaproteobacteria,2MJMW@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Aminotransferase class I and II	-	-	2.6.1.2	ko:K00814	ko00220,ko00250,ko00710,ko01100,ko01120,ko01200,ko01210,ko01230,map00220,map00250,map00710,map01100,map01120,map01200,map01210,map01230	M00171	R00258	RC00006,RC00008	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
k141_1427_1	1122963.AUHB01000001_gene428	5.21e-101	302.0	COG0500@1|root,COG2226@2|Bacteria,1MYUT@1224|Proteobacteria	1224|Proteobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
k141_1427_2	573569.F7308_0862	5.36e-71	229.0	COG1621@1|root,COG1621@2|Bacteria,1N5AZ@1224|Proteobacteria,1T49H@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	beta-fructofuranosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_1427_5	670307.HYPDE_37613	1.46e-08	60.1	COG1028@1|root,COG1028@2|Bacteria,1MUEV@1224|Proteobacteria,2TRCF@28211|Alphaproteobacteria	28211|Alphaproteobacteria	IQ	Acetoacetyl-CoA reductase	phbB	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	1.1.1.36	ko:K00023	ko00630,ko00650,ko01120,ko01200,map00630,map00650,map01120,map01200	M00373	R01779,R01977	RC00103,RC00117	ko00000,ko00001,ko00002,ko01000	-	-	-	adh_short_C2
k141_3125_1	273121.WS1610	1.31e-46	170.0	COG4206@1|root,COG4206@2|Bacteria,1QVV2@1224|Proteobacteria,43CBK@68525|delta/epsilon subdivisions,2YTB8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	TonB dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
k141_449_1	1121405.dsmv_2847	4.13e-73	230.0	COG1638@1|root,COG1638@2|Bacteria,1MVHC@1224|Proteobacteria,42N80@68525|delta/epsilon subdivisions,2WKQ7@28221|Deltaproteobacteria,2MHW5@213118|Desulfobacterales	28221|Deltaproteobacteria	G	Bacterial extracellular solute-binding protein, family 7	-	-	-	-	-	-	-	-	-	-	-	-	DctP
k141_1778_1	1304885.AUEY01000053_gene151	2.09e-62	204.0	COG1127@1|root,COG1127@2|Bacteria,1MUSD@1224|Proteobacteria,42NI4@68525|delta/epsilon subdivisions,2WKRT@28221|Deltaproteobacteria,2MIVB@213118|Desulfobacterales	28221|Deltaproteobacteria	Q	PFAM ABC transporter	-	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran,GGDEF
k141_1778_2	1202962.KB907152_gene1228	1.47e-29	108.0	COG1463@1|root,COG1463@2|Bacteria,1NCUG@1224|Proteobacteria,1SFF0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	MlaD protein	ttg2C	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
k141_1066_1	1224318.DT73_11735	9.82e-82	250.0	2BY42@1|root,32R2K@2|Bacteria,1MZU9@1224|Proteobacteria,1S84F@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_450_1	1167006.UWK_01609	5.47e-94	296.0	COG2838@1|root,COG2838@2|Bacteria,1MV6Q@1224|Proteobacteria,42MY0@68525|delta/epsilon subdivisions,2WM7X@28221|Deltaproteobacteria,2MIGK@213118|Desulfobacterales	28221|Deltaproteobacteria	C	isocitrate dehydrogenase, NADP-dependent, monomeric type	icd	-	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	IDH
k141_136_1	1304885.AUEY01000004_gene912	1.3e-134	392.0	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,42MSR@68525|delta/epsilon subdivisions,2WIXG@28221|Deltaproteobacteria,2MIJC@213118|Desulfobacterales	28221|Deltaproteobacteria	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
k141_136_2	1304885.AUEY01000004_gene911	1.85e-141	417.0	COG1960@1|root,COG1960@2|Bacteria,1MU20@1224|Proteobacteria,42Z3K@68525|delta/epsilon subdivisions,2WTSP@28221|Deltaproteobacteria,2MMNN@213118|Desulfobacterales	28221|Deltaproteobacteria	C	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_C,Acyl-CoA_dh_M,AcylCoA_DH_N
k141_1779_1	1232437.KL661989_gene459	1.33e-31	121.0	COG1252@1|root,COG1252@2|Bacteria,1QUKT@1224|Proteobacteria,42MAW@68525|delta/epsilon subdivisions,2WJCB@28221|Deltaproteobacteria,2MHYK@213118|Desulfobacterales	28221|Deltaproteobacteria	C	TIGRFAM Pyridine nucleotide-disulfide oxidoreductase family protein	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2
k141_1780_1	880072.Desac_0788	1.55e-45	164.0	COG4964@1|root,COG4964@2|Bacteria,1MV8G@1224|Proteobacteria,42PA6@68525|delta/epsilon subdivisions,2WIIY@28221|Deltaproteobacteria,2MQ7T@213462|Syntrophobacterales	28221|Deltaproteobacteria	U	Type II and III secretion system protein	-	-	-	ko:K02280	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	BON,Secretin,T2SS-T3SS_pil_N
k141_1780_2	243090.RB13104	1.28e-06	50.4	COG4964@1|root,COG4964@2|Bacteria,2IYED@203682|Planctomycetes	203682|Planctomycetes	U	Belongs to the GSP D family	-	-	-	ko:K02280	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	Secretin,T2SS-T3SS_pil_N
k141_1067_2	1121904.ARBP01000006_gene3789	1.18e-53	172.0	2CX7C@1|root,32T1D@2|Bacteria,4P5SV@976|Bacteroidetes,47W1M@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_1067_3	572544.Ilyop_0880	2.87e-50	167.0	COG1658@1|root,COG1658@2|Bacteria,378UX@32066|Fusobacteria	32066|Fusobacteria	J	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step	rnmV	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043822,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360	3.1.26.8	ko:K05985	-	-	-	-	ko00000,ko01000	-	-	-	DUF4093,Toprim,Toprim_4
k141_1067_4	484770.UFO1_1486	3.4e-29	107.0	COG2033@1|root,COG2033@2|Bacteria,1V7QP@1239|Firmicutes,4H52U@909932|Negativicutes	909932|Negativicutes	C	PFAM Desulfoferrodoxin, ferrous iron-binding region	nlr	-	1.15.1.2	ko:K05919	-	-	-	-	ko00000,ko01000	-	-	-	Desulfoferrodox
k141_3126_1	1121403.AUCV01000045_gene1165	2.21e-93	300.0	COG1629@1|root,COG4771@2|Bacteria,1MWKN@1224|Proteobacteria,42MNM@68525|delta/epsilon subdivisions,2WMEW@28221|Deltaproteobacteria,2MMGV@213118|Desulfobacterales	28221|Deltaproteobacteria	P	TonB dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
k141_1430_1	1188252.AJYK01000094_gene1577	5.41e-108	334.0	COG2246@1|root,COG2246@2|Bacteria,1R2TS@1224|Proteobacteria,1T5XD@1236|Gammaproteobacteria,1XTY2@135623|Vibrionales	135623|Vibrionales	S	GtrA-like protein	-	-	-	-	-	-	-	-	-	-	-	-	GtrA
k141_1068_1	1499967.BAYZ01000093_gene4035	6.5e-33	125.0	28RXC@1|root,2ZE9F@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_451_1	1173263.Syn7502_00092	7.48e-07	55.5	COG0715@1|root,COG1116@1|root,COG0715@2|Bacteria,COG1116@2|Bacteria	2|Bacteria	P	anion transmembrane transporter activity	nasD	-	3.6.3.36	ko:K02049,ko:K10831,ko:K11950,ko:K11952,ko:K11953,ko:K15576,ko:K15578,ko:K15598	ko00910,ko00920,ko02010,map00910,map00920,map02010	M00188,M00321,M00435,M00438,M00442	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.16,3.A.1.16.1,3.A.1.16.2,3.A.1.16.3,3.A.1.17,3.A.1.17.1,3.A.1.17.3,3.A.1.17.4,3.A.1.17.6	-	-	ABC_tran,NMT1
k141_451_2	1454004.AW11_01025	5.99e-81	251.0	COG0390@1|root,COG0390@2|Bacteria,1MV2N@1224|Proteobacteria,2VJX0@28216|Betaproteobacteria	28216|Betaproteobacteria	S	permease	ybbM	-	-	ko:K02069	-	M00211	-	-	ko00000,ko00002,ko02000	9.B.25.1	-	-	UPF0014
k141_451_3	1121405.dsmv_2578	9.36e-91	278.0	COG0484@1|root,COG0484@2|Bacteria,1MUZ4@1224|Proteobacteria,42NBY@68525|delta/epsilon subdivisions,2WJV2@28221|Deltaproteobacteria,2MIIH@213118|Desulfobacterales	28221|Deltaproteobacteria	O	heat shock protein DnaJ domain protein	-	-	-	ko:K03686,ko:K05516	-	-	-	-	ko00000,ko03029,ko03036,ko03110	-	-	-	DnaJ,DnaJ_C
k141_1069_1	909943.HIMB100_00011190	3.84e-121	363.0	COG0028@1|root,COG0028@2|Bacteria,1MWUB@1224|Proteobacteria,2TTAQ@28211|Alphaproteobacteria,4BRPM@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	EH	Belongs to the TPP enzyme family	xsc	-	2.3.3.15	ko:K03852	ko00430,map00430	-	R05651	RC02903,RC02909	ko00000,ko00001,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
k141_3128_1	1122194.AUHU01000003_gene1972	1.24e-18	87.4	2CPZ1@1|root,32SK5@2|Bacteria,1N2AX@1224|Proteobacteria,1SAFH@1236|Gammaproteobacteria,46BRK@72275|Alteromonadaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_452_1	29581.BW37_03743	1.9e-78	246.0	COG3437@1|root,COG3437@2|Bacteria,1MUB8@1224|Proteobacteria,2VH1F@28216|Betaproteobacteria,474G1@75682|Oxalobacteraceae	28216|Betaproteobacteria	T	HD domain	-	-	-	ko:K07814	-	-	-	-	ko00000,ko02022	-	-	-	DUF3369,GGDEF,HD,HD_5,Response_reg
k141_1781_1	767817.Desgi_4673	5.4e-141	409.0	COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,2497Z@186801|Clostridia,264HK@186807|Peptococcaceae	186801|Clostridia	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
k141_1781_2	1121396.KB893053_gene2388	5.58e-59	193.0	COG1180@1|root,COG1180@2|Bacteria,1NQC1@1224|Proteobacteria,42QX3@68525|delta/epsilon subdivisions,2WPC7@28221|Deltaproteobacteria,2MJMP@213118|Desulfobacterales	28221|Deltaproteobacteria	O	TIGRFAM anaerobic ribonucleoside-triphosphate reductase activating protein	pflA	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
k141_137_1	1265505.ATUG01000001_gene3817	3.91e-103	308.0	COG1536@1|root,COG1536@2|Bacteria,1MV9X@1224|Proteobacteria,42MS3@68525|delta/epsilon subdivisions,2WMCR@28221|Deltaproteobacteria,2MJ83@213118|Desulfobacterales	28221|Deltaproteobacteria	N	flagellar motor switch protein FliG	fliG	-	-	ko:K02410	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliG_C,FliG_M,FliG_N
k141_137_3	1121396.KB893061_gene2692	2.7e-212	599.0	COG1157@1|root,COG1157@2|Bacteria,1MUH6@1224|Proteobacteria,42M0K@68525|delta/epsilon subdivisions,2WISR@28221|Deltaproteobacteria,2MIRR@213118|Desulfobacterales	28221|Deltaproteobacteria	NU	ATP synthase alpha beta family, nucleotide-binding domain	fliI	-	3.6.3.14	ko:K02412	ko02040,map02040	-	-	-	ko00000,ko00001,ko01000,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	ATP-synt_ab,ATP-synt_ab_N
k141_3129_1	1232437.KL661986_gene3678	7.76e-116	342.0	COG0247@1|root,COG0247@2|Bacteria,1MUMH@1224|Proteobacteria,42R1T@68525|delta/epsilon subdivisions,2WN88@28221|Deltaproteobacteria,2MN72@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Cysteine-rich domain	-	-	1.8.98.1	ko:K08264	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	-	R04540	RC00011	ko00000,ko00001,ko01000	-	-	-	CCG,Fer4_8
k141_3373_85	1294142.CINTURNW_3659	2.47e-168	487.0	COG0402@1|root,COG0402@2|Bacteria,1TP43@1239|Firmicutes,248IX@186801|Clostridia,36FIQ@31979|Clostridiaceae	186801|Clostridia	F	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine	ssnA	-	3.5.4.40	ko:K20810	ko00130,ko01110,map00130,map01110	-	R10695	RC00477	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
k141_3373_86	796940.HMPREF9628_01735	2.56e-222	635.0	COG3829@1|root,COG3829@2|Bacteria,1TP0E@1239|Firmicutes,247MB@186801|Clostridia,25STW@186804|Peptostreptococcaceae	186801|Clostridia	KT	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HTH_8,PAS_8,Sigma54_activat
k141_3373_87	796940.HMPREF9628_01734	1.96e-79	248.0	COG1975@1|root,COG1975@2|Bacteria,1URM5@1239|Firmicutes,24AHV@186801|Clostridia,25RYR@186804|Peptostreptococcaceae	186801|Clostridia	O	XdhC and CoxI family	-	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	XdhC_C,XdhC_CoxI
k141_3373_88	86416.Clopa_0430	4.25e-113	340.0	COG3608@1|root,COG3608@2|Bacteria,1TRKT@1239|Firmicutes,2492W@186801|Clostridia,36E0K@31979|Clostridiaceae	186801|Clostridia	S	Selenium-dependent molybdenum hydroxylase system protein, YqeB family	-	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	NTP_transf_3
k141_3373_89	1121342.AUCO01000005_gene226	2.29e-43	154.0	COG1192@1|root,COG1192@2|Bacteria,1UI78@1239|Firmicutes,25ECF@186801|Clostridia,36I2D@31979|Clostridiaceae	186801|Clostridia	D	Involved in chromosome partitioning	yqeC	-	-	-	-	-	-	-	-	-	-	-	-
k141_3373_90	1304284.L21TH_1802	9.78e-125	372.0	COG5438@1|root,COG5438@2|Bacteria,1TPEV@1239|Firmicutes,249SW@186801|Clostridia,36GKC@31979|Clostridiaceae	186801|Clostridia	S	YibE F family protein	-	-	-	-	-	-	-	-	-	-	-	-	YibE_F
k141_3373_91	926561.KB900617_gene1579	1.5e-187	540.0	COG1388@1|root,COG1785@1|root,COG1388@2|Bacteria,COG1785@2|Bacteria,1TQCI@1239|Firmicutes,248GG@186801|Clostridia,3WAZT@53433|Halanaerobiales	186801|Clostridia	P	Belongs to the alkaline phosphatase family	-	-	3.1.3.1	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	M00126	R02135,R04620	RC00017	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	-	-	-	Alk_phosphatase
k141_3373_92	871963.Desdi_0151	2.36e-59	223.0	COG0840@1|root,COG0840@2|Bacteria,1TP5A@1239|Firmicutes,247S3@186801|Clostridia,260AA@186807|Peptococcaceae	186801|Clostridia	NT	Methyl-accepting chemotaxis protein (MCP) signaling domain	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal,dCache_1,dCache_3
k141_5418_1	1116375.VEJY3_08630	1.41e-259	726.0	COG0524@1|root,COG3892@1|root,COG0524@2|Bacteria,COG3892@2|Bacteria,1MV6I@1224|Proteobacteria,1RQGH@1236|Gammaproteobacteria,1XUC3@135623|Vibrionales	135623|Vibrionales	G	Uncharacterized protein conserved in bacteria (DUF2090)	-	-	2.7.1.92	ko:K03338	ko00562,ko01100,ko01120,map00562,map01100,map01120	-	R05661	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	DUF2090,PfkB
k141_5418_2	1280001.BAOA01000157_gene4739	2.66e-109	322.0	COG0730@1|root,COG0730@2|Bacteria,1MVY3@1224|Proteobacteria,1S21M@1236|Gammaproteobacteria,1XUTI@135623|Vibrionales	135623|Vibrionales	S	Sulfite exporter TauE/SafE	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
k141_3374_2	1134474.O59_001328	1.95e-10	68.9	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1FG8F@10|Cellvibrio	1236|Gammaproteobacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_3,PAS_4,PAS_9
k141_3375_1	1517681.HW45_03795	3e-54	184.0	COG5421@1|root,COG5421@2|Bacteria,1R25F@1224|Proteobacteria,1RZQP@1236|Gammaproteobacteria,1XV94@135623|Vibrionales	135623|Vibrionales	L	Domain of unknown function (DUF4277)	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DUF4277
k141_5421_1	221988.MS2324	1.26e-14	69.3	COG3254@1|root,COG3254@2|Bacteria,1RGYV@1224|Proteobacteria,1S6AI@1236|Gammaproteobacteria,1YA7B@135625|Pasteurellales	135625|Pasteurellales	G	Involved in the anomeric conversion of L-rhamnose	rhaM	-	5.1.3.32	ko:K03534	-	-	R10819	RC00563	ko00000,ko01000	-	-	-	rhaM
k141_5421_2	595494.Tola_1041	2.31e-155	446.0	COG0697@1|root,2Z7ID@2|Bacteria,1MXB3@1224|Proteobacteria,1RQV6@1236|Gammaproteobacteria	1236|Gammaproteobacteria	U	Uptake of L-rhamnose across the boundary membrane with the concomitant transport of protons into the cell (symport system)	rhaT	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0008643,GO:0008645,GO:0015291,GO:0015293,GO:0015749,GO:0015762,GO:0016020,GO:0022804,GO:0022857,GO:0034219,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944	-	ko:K02856	-	-	-	-	ko00000,ko02000	2.A.7.6	-	iECSE_1348.ECSE_4196,iEcE24377_1341.EcE24377A_4438,iYL1228.KPN_04216	RhaT
k141_3378_1	558152.IQ37_11670	7.53e-08	53.5	COG2207@1|root,COG3449@1|root,COG2207@2|Bacteria,COG3449@2|Bacteria,4NHWS@976|Bacteroidetes,1I02Q@117743|Flavobacteriia,3ZPQX@59732|Chryseobacterium	976|Bacteroidetes	K	Bacterial transcription activator, effector binding domain	-	-	-	ko:K13652	-	-	-	-	ko00000,ko03000	-	-	-	GyrI-like,HTH_18,HTH_AraC
k141_3378_2	641491.DND132_2748	8.57e-75	237.0	COG0506@1|root,COG0506@2|Bacteria,1R8VR@1224|Proteobacteria,42P21@68525|delta/epsilon subdivisions,2WJU2@28221|Deltaproteobacteria,2M89P@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	Proline dehydrogenase	-	-	-	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	-	R10507	RC00083	ko00000,ko00001,ko01000	-	-	-	Pro_dh
k141_3381_1	595494.Tola_1946	4.52e-143	416.0	COG2211@1|root,COG2211@2|Bacteria,1MVUM@1224|Proteobacteria,1RP5J@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	COG2211 Na melibiose symporter and related transporters	-	-	-	ko:K03292,ko:K16139	-	-	-	-	ko00000,ko02000	2.A.2	-	-	MFS_2
k141_5422_1	1304885.AUEY01000002_gene396	1.32e-161	471.0	COG1797@1|root,COG1797@2|Bacteria,1MV7Z@1224|Proteobacteria,42M8T@68525|delta/epsilon subdivisions,2WIXE@28221|Deltaproteobacteria,2MHZW@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source	cbiA	-	6.3.5.11,6.3.5.9	ko:K02224	ko00860,ko01100,ko01120,map00860,map01100,map01120	-	R05224,R05815	RC00010,RC01301	ko00000,ko00001,ko01000	-	-	-	AAA_26,CbiA,GATase_3
k141_5422_2	1121405.dsmv_2207	1.56e-21	86.7	2DPAJ@1|root,33191@2|Bacteria,1N72K@1224|Proteobacteria,42WBC@68525|delta/epsilon subdivisions,2WRZF@28221|Deltaproteobacteria,2MM3V@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Dissimilatory sulfite reductase	dsrD	-	-	-	-	-	-	-	-	-	-	-	DsrD
k141_5422_3	933262.AXAM01000001_gene349	2.04e-255	702.0	COG2221@1|root,COG2221@2|Bacteria,1MVZQ@1224|Proteobacteria,42N7B@68525|delta/epsilon subdivisions,2WJYE@28221|Deltaproteobacteria,2MI4D@213118|Desulfobacterales	28221|Deltaproteobacteria	C	TIGRFAM sulfite reductase, dissimilatory-type beta subunit	dsrB	-	1.8.99.5	ko:K11181	ko00633,ko00920,ko01100,ko01120,map00633,map00920,map01100,map01120	M00596	R00295,R00861,R08035	RC00065,RC01760	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_7,NIR_SIR,NIR_SIR_ferr
k141_5422_4	1304885.AUEY01000002_gene393	7.63e-278	764.0	COG2221@1|root,COG2221@2|Bacteria,1MWY5@1224|Proteobacteria,42MRB@68525|delta/epsilon subdivisions,2WIZD@28221|Deltaproteobacteria,2MIFB@213118|Desulfobacterales	28221|Deltaproteobacteria	C	TIGRFAM sulfite reductase, dissimilatory-type alpha subunit	dsrA	-	1.8.99.5	ko:K11180	ko00633,ko00920,ko01100,ko01120,map00633,map00920,map01100,map01120	M00596	R00295,R00861,R08035	RC00065,RC01760	ko00000,ko00001,ko00002,ko01000	-	-	-	NIR_SIR,NIR_SIR_ferr
k141_5423_1	34506.g925	5.36e-44	160.0	COG1004@1|root,COG1088@1|root,KOG0747@2759|Eukaryota,KOG2666@2759|Eukaryota,39ADA@33154|Opisthokonta,3BF2W@33208|Metazoa,3CWS2@33213|Bilateria,40FTF@6231|Nematoda,1KYEF@119089|Chromadorea,40UIK@6236|Rhabditida	33208|Metazoa	G	Male sterility protein	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase_2,GDP_Man_Dehyd,UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
k141_5423_2	1195246.AGRI_04692	8.58e-120	348.0	COG1209@1|root,COG1209@2|Bacteria,1MU0X@1224|Proteobacteria,1RMTR@1236|Gammaproteobacteria,4640A@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis	rmlA	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
k141_3383_1	1348635.BBJY01000003_gene3745	2e-117	344.0	COG1120@1|root,COG1120@2|Bacteria,1MVKU@1224|Proteobacteria,1RN86@1236|Gammaproteobacteria,1XVHM@135623|Vibrionales	135623|Vibrionales	HP	ABC-type cobalamin Fe3 -siderophores transport systems, ATPase	-	-	3.6.3.34	ko:K02013	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	ABC_tran
k141_3383_2	1191299.AJYX01000065_gene3696	9.91e-185	521.0	COG0609@1|root,COG0609@2|Bacteria,1MV9W@1224|Proteobacteria,1RMST@1236|Gammaproteobacteria,1XSQQ@135623|Vibrionales	135623|Vibrionales	P	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily	-	-	-	ko:K02015	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	FecCD
k141_3383_3	1348635.BBJY01000003_gene3744	1.36e-205	575.0	COG0614@1|root,COG0614@2|Bacteria,1MUSZ@1224|Proteobacteria,1RPUH@1236|Gammaproteobacteria,1XVTG@135623|Vibrionales	135623|Vibrionales	P	ABC-type Fe3 -hydroxamate transport system, periplasmic component	-	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
k141_5424_1	675806.VII_002941	1.57e-242	681.0	COG4623@1|root,COG4623@2|Bacteria,1MWDS@1224|Proteobacteria,1RM8W@1236|Gammaproteobacteria,1XTC4@135623|Vibrionales	135623|Vibrionales	M	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella	mltF	GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009253,GO:0009279,GO:0016020,GO:0019867,GO:0030203,GO:0030312,GO:0030313,GO:0031975,GO:0043170,GO:0044462,GO:0044464,GO:0071704,GO:0071944,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575	-	ko:K18691	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	SBP_bac_3,SLT
k141_5424_2	675814.VIC_001964	3.69e-84	252.0	COG0590@1|root,COG0590@2|Bacteria,1RGU0@1224|Proteobacteria,1S60Z@1236|Gammaproteobacteria,1XUA6@135623|Vibrionales	135623|Vibrionales	FJ	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)	tadA	-	3.5.4.33	ko:K11991	-	-	R10223	RC00477	ko00000,ko01000,ko03016	-	-	-	MafB19-deam
k141_5424_4	223926.28805645	2.44e-85	274.0	COG3156@1|root,COG3156@2|Bacteria,1QJFS@1224|Proteobacteria,1THF6@1236|Gammaproteobacteria,1XV93@135623|Vibrionales	135623|Vibrionales	U	type II secretion system protein K	VP0659	-	-	-	-	-	-	-	-	-	-	-	-
k141_5424_7	675813.VIB_001794	1.89e-219	612.0	COG0484@1|root,COG0484@2|Bacteria,1MVMS@1224|Proteobacteria,1RNHY@1236|Gammaproteobacteria,1XT3G@135623|Vibrionales	135623|Vibrionales	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	GO:0006457,GO:0008150,GO:0009987	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
k141_5424_8	1348635.BBJY01000020_gene2763	0.0	1068.0	COG0443@1|root,COG0443@2|Bacteria,1MVEN@1224|Proteobacteria,1RMDD@1236|Gammaproteobacteria,1XUDT@135623|Vibrionales	135623|Vibrionales	O	Heat shock 70 kDa protein	dnaK	GO:0006457,GO:0008150,GO:0009987	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
k141_5424_9	298386.PBPRB0505	3.87e-111	331.0	COG2358@1|root,COG2358@2|Bacteria,1MXW1@1224|Proteobacteria,1RYBC@1236|Gammaproteobacteria,1XTNX@135623|Vibrionales	135623|Vibrionales	S	ABC transporter, phosphonate, periplasmic substrate-binding protein	-	-	-	ko:K07080	-	-	-	-	ko00000	-	-	-	NMT1_3
k141_5424_10	675814.VIC_000811	2.85e-133	385.0	COG2239@1|root,COG2239@2|Bacteria,1MW24@1224|Proteobacteria,1RYH1@1236|Gammaproteobacteria,1XVN6@135623|Vibrionales	135623|Vibrionales	P	Mg Co Ni transporter MgtE (Contains CBS domain)	VP2469	-	-	ko:K06213	-	-	-	-	ko00000,ko02000	1.A.26.1	-	-	MgtE
k141_5424_11	55601.VANGNB10_cI0736	1.71e-100	296.0	COG0576@1|root,COG0576@2|Bacteria,1RH8T@1224|Proteobacteria,1S5W5@1236|Gammaproteobacteria,1XT2V@135623|Vibrionales	135623|Vibrionales	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	GO:0000166,GO:0000774,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0008150,GO:0009987,GO:0017076,GO:0030234,GO:0030554,GO:0036094,GO:0044424,GO:0044444,GO:0044464,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
k141_5424_12	870967.VIS19158_05778	2.32e-171	483.0	COG0061@1|root,COG0061@2|Bacteria,1MUBC@1224|Proteobacteria,1RP84@1236|Gammaproteobacteria,1XTTS@135623|Vibrionales	135623|Vibrionales	F	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	nadK	-	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	NAD_kinase
k141_5424_13	675813.VIB_001798	3.78e-294	815.0	COG0497@1|root,COG0497@2|Bacteria,1MUNP@1224|Proteobacteria,1RNPZ@1236|Gammaproteobacteria,1XSEX@135623|Vibrionales	135623|Vibrionales	L	May be involved in recombinational repair of damaged DNA	recN	-	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,SMC_N
k141_5424_14	675815.VOA_000779	5.89e-58	181.0	COG2913@1|root,COG2913@2|Bacteria,1N6YW@1224|Proteobacteria,1SCTT@1236|Gammaproteobacteria,1XXFF@135623|Vibrionales	135623|Vibrionales	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamE	-	-	ko:K06186	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	SmpA_OmlA
k141_5424_15	1187848.AJYQ01000099_gene2384	2.38e-40	136.0	COG2914@1|root,COG2914@2|Bacteria,1MZCH@1224|Proteobacteria,1SCHG@1236|Gammaproteobacteria,1XXAY@135623|Vibrionales	135623|Vibrionales	S	Belongs to the UPF0125 (RnfH) family	yfjF	-	-	ko:K09801	-	-	-	-	ko00000	-	-	-	Ub-RnfH
k141_5424_16	223926.28805631	3.53e-76	230.0	COG2867@1|root,COG2867@2|Bacteria,1RGUH@1224|Proteobacteria,1S61C@1236|Gammaproteobacteria,1XWWV@135623|Vibrionales	135623|Vibrionales	I	oligoketide cyclase lipid transport protein	ratA	GO:0003674,GO:0005488,GO:0006417,GO:0006446,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0043021,GO:0043023,GO:0044877,GO:0045947,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:2000112,GO:2000113	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc
k141_5424_17	945550.VISI1226_15066	7e-96	281.0	COG0691@1|root,COG0691@2|Bacteria,1RDFP@1224|Proteobacteria,1S3PT@1236|Gammaproteobacteria,1XTV7@135623|Vibrionales	135623|Vibrionales	J	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene	smpB	-	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
k141_5424_18	758.BBIX01000008_gene1073	3.03e-13	64.7	2A60M@1|root,30USV@2|Bacteria,1QI8E@1224|Proteobacteria,1TG2I@1236|Gammaproteobacteria,1YANJ@135625|Pasteurellales	135625|Pasteurellales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_5425_1	765911.Thivi_0693	2.27e-97	324.0	COG0784@1|root,COG2198@1|root,COG4564@1|root,COG5002@1|root,COG0784@2|Bacteria,COG2198@2|Bacteria,COG4564@2|Bacteria,COG5002@2|Bacteria,1NC9X@1224|Proteobacteria,1SVEC@1236|Gammaproteobacteria,1X2V3@135613|Chromatiales	135613|Chromatiales	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
k141_3384_1	595494.Tola_2293	2.93e-95	288.0	COG1454@1|root,COG1454@2|Bacteria,1MVPH@1224|Proteobacteria,1RMVU@1236|Gammaproteobacteria,1Y6CX@135624|Aeromonadales	135624|Aeromonadales	C	Iron-containing alcohol dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Fe-ADH
k141_3384_3	945550.VISI1226_10947	0.0	938.0	COG2905@1|root,COG2905@2|Bacteria,1MW8U@1224|Proteobacteria,1RPSJ@1236|Gammaproteobacteria,1XSDF@135623|Vibrionales	135623|Vibrionales	T	containing cAMP-binding and CBS domains	-	-	-	ko:K07182	-	-	-	-	ko00000	-	-	-	CBS,DUF294,DUF294_C,cNMP_binding
k141_3384_4	675816.VIA_001392	8.83e-88	266.0	COG0847@1|root,COG0847@2|Bacteria,1RAF1@1224|Proteobacteria,1S20V@1236|Gammaproteobacteria,1XSA6@135623|Vibrionales	135623|Vibrionales	L	COG0847 DNA polymerase III, epsilon subunit and related 3'-5' exonucleases	-	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	RNase_T
k141_3384_5	1348635.BBJY01000011_gene1199	4.88e-223	640.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,1XU8V@135623|Vibrionales	135623|Vibrionales	NT	methyl-accepting chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal,dCache_1
k141_3384_6	380703.AHA_2689	1.9e-300	854.0	COG1472@1|root,COG1472@2|Bacteria,1MVIV@1224|Proteobacteria,1RMA0@1236|Gammaproteobacteria,1Y4C8@135624|Aeromonadales	135624|Aeromonadales	G	Fibronectin type III-like domain	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
k141_2745_1	1123248.KB893359_gene2005	4.24e-47	166.0	COG2272@1|root,COG2272@2|Bacteria,4NG5B@976|Bacteroidetes,1IQQB@117747|Sphingobacteriia	976|Bacteroidetes	I	Belongs to the type-B carboxylesterase lipase family	-	-	-	ko:K03929	-	-	-	-	ko00000,ko01000	-	CE10	-	COesterase
k141_372_1	55601.VANGNB10_cII0555c	2.33e-72	227.0	COG2390@1|root,COG2390@2|Bacteria,1MX3F@1224|Proteobacteria,1RMEZ@1236|Gammaproteobacteria,1XT80@135623|Vibrionales	135623|Vibrionales	K	Transcriptional regulator, contains sigma factor-related N-terminal domain	lsrR	-	-	-	-	-	-	-	-	-	-	-	HTH_28,Sugar-bind
k141_2052_1	1121396.KB893092_gene3355	1.16e-86	278.0	COG3034@1|root,COG4319@1|root,COG3034@2|Bacteria,COG4319@2|Bacteria,1N2B6@1224|Proteobacteria,42QS4@68525|delta/epsilon subdivisions,2WKXW@28221|Deltaproteobacteria,2MITF@213118|Desulfobacterales	28221|Deltaproteobacteria	S	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
k141_54_1	1095769.CAHF01000006_gene1998	2.59e-25	106.0	COG2206@1|root,COG3437@1|root,COG2206@2|Bacteria,COG3437@2|Bacteria,1MV37@1224|Proteobacteria,2VJ21@28216|Betaproteobacteria,476NW@75682|Oxalobacteraceae	28216|Betaproteobacteria	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HD,HD_5
k141_54_2	675815.VOA_000968	3.53e-276	762.0	COG0364@1|root,COG0364@2|Bacteria,1MUN0@1224|Proteobacteria,1RN76@1236|Gammaproteobacteria,1XSC7@135623|Vibrionales	135623|Vibrionales	G	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone	zwf	-	1.1.1.363,1.1.1.49	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	M00004,M00006,M00008	R00835,R02736,R10907	RC00001,RC00066	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	G6PD_C,G6PD_N
k141_721_1	177437.HRM2_16110	1.23e-104	310.0	COG0730@1|root,COG0730@2|Bacteria,1N2QF@1224|Proteobacteria,42N53@68525|delta/epsilon subdivisions,2WKG8@28221|Deltaproteobacteria,2MHNP@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Sulfite exporter TauE/SafE	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
k141_4117_1	1121396.KB892935_gene3844	1.17e-98	295.0	COG0535@1|root,COG0535@2|Bacteria,1NDQM@1224|Proteobacteria,42YEG@68525|delta/epsilon subdivisions,2WUNR@28221|Deltaproteobacteria,2MMSQ@213118|Desulfobacterales	28221|Deltaproteobacteria	S	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_1046_1	502558.EGYY_23010	1.35e-97	301.0	COG1902@1|root,COG1902@2|Bacteria,2GK8E@201174|Actinobacteria,4CU83@84998|Coriobacteriia	84998|Coriobacteriia	C	NADH flavin oxidoreductase	-	-	1.3.1.31,1.3.1.34	ko:K00219,ko:K10797	ko00360,ko01120,map00360,map01120	-	R02252	RC00669	ko00000,ko00001,ko01000	-	-	-	Oxidored_FMN,Pyr_redox_2
k141_1046_2	177439.DP1397	4.22e-88	275.0	COG1114@1|root,COG1114@2|Bacteria,1MVIF@1224|Proteobacteria,42M3P@68525|delta/epsilon subdivisions,2WQZ6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Component of the transport system for branched-chain amino acids	-	-	-	ko:K03311	-	-	-	-	ko00000	2.A.26	-	-	Branch_AA_trans
k141_2053_1	1265505.ATUG01000001_gene3722	2.32e-169	499.0	COG0741@1|root,COG1388@1|root,COG0741@2|Bacteria,COG1388@2|Bacteria,1MWKE@1224|Proteobacteria,42M5C@68525|delta/epsilon subdivisions,2WJ54@28221|Deltaproteobacteria,2MJ3U@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Lytic transglycosylase catalytic	mltD2	-	-	ko:K08307	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	LysM,SLT
k141_1734_2	1348635.BBJY01000002_gene3478	1.42e-165	471.0	COG1477@1|root,COG1477@2|Bacteria,1MW6K@1224|Proteobacteria,1RNMZ@1236|Gammaproteobacteria,1XSQ4@135623|Vibrionales	135623|Vibrionales	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	apbE	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
k141_1734_3	672.VV93_v1c23000	3.17e-153	446.0	COG2199@1|root,COG2204@1|root,COG2204@2|Bacteria,COG3706@2|Bacteria,1MXBG@1224|Proteobacteria,1RNJA@1236|Gammaproteobacteria,1XSJA@135623|Vibrionales	135623|Vibrionales	T	COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Response_reg
k141_1734_4	945550.VISI1226_07902	7.99e-171	486.0	COG0389@1|root,COG0389@2|Bacteria,1MUUH@1224|Proteobacteria,1RMFM@1236|Gammaproteobacteria,1XTDB@135623|Vibrionales	135623|Vibrionales	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	dinB	-	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
k141_1734_5	55601.VANGNB10_cI2072c	8.07e-48	165.0	28HMH@1|root,2Z7W2@2|Bacteria,1R7XG@1224|Proteobacteria,1S0FH@1236|Gammaproteobacteria,1XTTQ@135623|Vibrionales	135623|Vibrionales	S	Protein of unknown function (DUF2884)	VP2339	-	-	-	-	-	-	-	-	-	-	-	DUF2884
k141_1734_6	1219077.VAZ01S_010_01100	2.82e-231	648.0	COG0733@1|root,COG0733@2|Bacteria,1MUZJ@1224|Proteobacteria,1RPCT@1236|Gammaproteobacteria,1XT5X@135623|Vibrionales	135623|Vibrionales	S	COG0733 Na -dependent transporters of the SNF family	-	-	-	ko:K03308	-	-	-	-	ko00000	2.A.22.4,2.A.22.5	-	-	SNF
k141_1734_7	675813.VIB_000645	3.19e-178	505.0	COG3608@1|root,COG3608@2|Bacteria,1MUAA@1224|Proteobacteria,1RNQQ@1236|Gammaproteobacteria,1XTI2@135623|Vibrionales	135623|Vibrionales	S	Succinylglutamate desuccinylase aspartoacylase family protein	-	-	-	ko:K06987	-	-	-	-	ko00000	-	-	-	AstE_AspA
k141_1734_8	243277.VC_2281	1.31e-192	537.0	COG0189@1|root,COG0189@2|Bacteria,1MX62@1224|Proteobacteria,1RM8B@1236|Gammaproteobacteria,1XT40@135623|Vibrionales	135623|Vibrionales	F	Belongs to the RimK family	rimK	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016874,GO:0016879,GO:0016881,GO:0018169,GO:0018410,GO:0019538,GO:0031668,GO:0033554,GO:0036211,GO:0043170,GO:0043412,GO:0043687,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:0070739,GO:0071496,GO:0071704,GO:0140096,GO:1901564	-	ko:K05844	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	RimK
k141_1734_9	55601.VANGNB10_cI2066	6.86e-64	199.0	COG4067@1|root,COG4067@2|Bacteria,1RGX8@1224|Proteobacteria,1S5YR@1236|Gammaproteobacteria,1XUM3@135623|Vibrionales	135623|Vibrionales	O	protein conserved in archaea	-	-	-	-	-	-	-	-	-	-	-	-	Zn_protease
k141_1734_10	945550.VISI1226_07947	4.31e-249	696.0	COG2195@1|root,COG2195@2|Bacteria,1MUWK@1224|Proteobacteria,1RP5F@1236|Gammaproteobacteria,1XT90@135623|Vibrionales	135623|Vibrionales	E	aminoacyl-histidine dipeptidase	pepD	-	-	ko:K01270	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
k141_1734_12	243277.VC_2277	8.09e-103	298.0	COG2236@1|root,COG2236@2|Bacteria,1MWNE@1224|Proteobacteria,1RQ4C@1236|Gammaproteobacteria,1XSMG@135623|Vibrionales	135623|Vibrionales	F	Acts on guanine, xanthine and to a lesser extent hypoxanthine	gpt	GO:0000310,GO:0003674,GO:0003824,GO:0004422,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006166,GO:0006177,GO:0006188,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032261,GO:0032263,GO:0032264,GO:0032265,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0043094,GO:0043101,GO:0043173,GO:0043174,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046040,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097292,GO:0097293,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.4.2.22	ko:K00769	ko00230,ko01100,ko01110,map00230,map01100,map01110	-	R01229,R02142	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
k141_1734_13	945550.VISI1226_07962	1.1e-206	582.0	COG1073@1|root,COG1073@2|Bacteria,1N5CG@1224|Proteobacteria,1RR2Y@1236|Gammaproteobacteria,1XSG1@135623|Vibrionales	135623|Vibrionales	S	Belongs to the UPF0255 family	frsA	-	-	ko:K11750	-	-	-	-	ko00000,ko01000	-	-	-	DUF1100
k141_1734_14	870967.VIS19158_12463	2.13e-38	133.0	292QM@1|root,2ZQ8E@2|Bacteria,1N4UT@1224|Proteobacteria,1S3WH@1236|Gammaproteobacteria,1XY3C@135623|Vibrionales	135623|Vibrionales	K	Binds to the sigma-S subunit of RNA polymerase, activating expression of sigma-S-regulated genes. Stimulates RNA polymerase holoenzyme formation and may bind to several other sigma factors, such as sigma-70 and sigma-32	crl	GO:0003674,GO:0003700,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2001141	-	ko:K11926	-	-	-	-	ko00000,ko03000	-	-	-	Crl
k141_1734_16	675816.VIA_003767	1.77e-220	617.0	COG0014@1|root,COG0014@2|Bacteria,1MUGJ@1224|Proteobacteria,1RMAY@1236|Gammaproteobacteria,1XT6D@135623|Vibrionales	135623|Vibrionales	E	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate	proA	GO:0003674,GO:0003824,GO:0004350,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0018130,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.2.1.41	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	M00015	R03313	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
k141_1734_17	870967.VIS19158_12448	5.52e-94	275.0	COG1327@1|root,COG1327@2|Bacteria,1RE7V@1224|Proteobacteria,1S3P9@1236|Gammaproteobacteria,1XT5J@135623|Vibrionales	135623|Vibrionales	K	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes	nrdR	-	-	ko:K07738	-	-	-	-	ko00000,ko03000	-	-	-	ATP-cone
k141_1734_18	1348635.BBJY01000002_gene3454	1.63e-171	489.0	COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,1MUWT@1224|Proteobacteria,1RN2M@1236|Gammaproteobacteria,1XST0@135623|Vibrionales	135623|Vibrionales	H	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate	ribD	-	1.1.1.193,3.5.4.26	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C,dCMP_cyt_deam_1
k141_1734_19	55601.VANGNB10_cI2056c	2.94e-118	342.0	COG0307@1|root,COG0307@2|Bacteria,1MUMB@1224|Proteobacteria,1RMSY@1236|Gammaproteobacteria,1XTJZ@135623|Vibrionales	135623|Vibrionales	H	Riboflavin synthase alpha chain	ribE	-	2.5.1.9	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00066	RC00958,RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	Lum_binding
k141_1734_20	675815.VOA_002599	2.61e-217	605.0	COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,1MU8P@1224|Proteobacteria,1RQ49@1236|Gammaproteobacteria,1XSY7@135623|Vibrionales	135623|Vibrionales	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	ribB	-	3.5.4.25,4.1.99.12	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	DHBP_synthase,GTP_cyclohydro2
k141_1734_21	945550.VISI1226_08002	1.96e-95	279.0	COG0054@1|root,COG0054@2|Bacteria,1RD9J@1224|Proteobacteria,1S3WD@1236|Gammaproteobacteria,1XTEC@135623|Vibrionales	135623|Vibrionales	H	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin	ribH	GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.78	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R04457	RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	DMRL_synthase
k141_1734_22	672.VV93_v1c08040	1.18e-91	270.0	COG0781@1|root,COG0781@2|Bacteria,1RHFZ@1224|Proteobacteria,1S6AJ@1236|Gammaproteobacteria,1XSA8@135623|Vibrionales	135623|Vibrionales	K	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons	nusB	GO:0006139,GO:0006351,GO:0006353,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576	-	ko:K03625	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusB
k141_1734_23	675813.VIB_000660	1.69e-131	385.0	COG0611@1|root,COG0611@2|Bacteria,1MU9X@1224|Proteobacteria,1RNHU@1236|Gammaproteobacteria,1XTKW@135623|Vibrionales	135623|Vibrionales	F	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1	thiL	-	2.7.4.16	ko:K00946	ko00730,ko01100,map00730,map01100	M00127	R00617	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
k141_1734_24	675815.VOA_002595	2.71e-81	244.0	COG1267@1|root,COG1267@2|Bacteria,1MZJA@1224|Proteobacteria,1S68A@1236|Gammaproteobacteria,1XTFB@135623|Vibrionales	135623|Vibrionales	I	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)	pgpA	-	3.1.3.27	ko:K01095	ko00564,ko01100,map00564,map01100	-	R02029	RC00017	ko00000,ko00001,ko01000	-	-	-	PgpA
k141_1734_25	1348635.BBJY01000002_gene3446	0.0	1298.0	COG2844@1|root,COG2844@2|Bacteria,1MV54@1224|Proteobacteria,1RN5T@1236|Gammaproteobacteria,1XU15@135623|Vibrionales	135623|Vibrionales	O	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen	glnD	GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006541,GO:0006542,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008773,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0070569,GO:0071704,GO:0140096,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.7.59	ko:K00990	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	-	-	-	ACT,GlnD_UR_UTase,HD,NTP_transf_2
k141_1734_26	55601.VANGNB10_cI2048	5.27e-177	496.0	COG0024@1|root,COG0024@2|Bacteria,1MU99@1224|Proteobacteria,1RMHN@1236|Gammaproteobacteria,1XU50@135623|Vibrionales	135623|Vibrionales	E	Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
k141_1734_28	1219065.VPR01S_10_00690	4.48e-162	458.0	COG0264@1|root,COG0264@2|Bacteria,1MUS2@1224|Proteobacteria,1RPBJ@1236|Gammaproteobacteria,1XSH9@135623|Vibrionales	135623|Vibrionales	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
k141_1049_1	1235802.C823_02670	2.7e-87	273.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247PY@186801|Clostridia,25V0B@186806|Eubacteriaceae	186801|Clostridia	V	ABC transporter, ATP-binding protein	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
k141_4207_9	1051646.VITU9109_25270	0.0	1043.0	COG0326@1|root,COG0326@2|Bacteria,1MUUE@1224|Proteobacteria,1RNWD@1236|Gammaproteobacteria,1XSVC@135623|Vibrionales	135623|Vibrionales	O	Molecular chaperone. Has ATPase activity	htpG	GO:0006457,GO:0008150,GO:0009987	-	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	-	-	-	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	-	-	-	HATPase_c,HATPase_c_3,HSP90
k141_4207_10	345073.VC395_0999	4.22e-72	231.0	COG3710@1|root,COG3710@2|Bacteria,1QXRC@1224|Proteobacteria,1SDUS@1236|Gammaproteobacteria,1XUD7@135623|Vibrionales	135623|Vibrionales	K	COG3710 DNA-binding winged-HTH domains	toxR	GO:0000156,GO:0000160,GO:0003674,GO:0006355,GO:0007154,GO:0007165,GO:0008150,GO:0009405,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0023052,GO:0031323,GO:0031326,GO:0035556,GO:0044419,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0051704,GO:0051716,GO:0060089,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141	-	ko:K10921	ko05111,map05111	-	-	-	ko00000,ko00001	-	-	-	Trans_reg_C
k141_4207_11	55601.VANGNB10_cI0856c	1.3e-66	207.0	2AVZE@1|root,31MTT@2|Bacteria,1QJJZ@1224|Proteobacteria,1THKE@1236|Gammaproteobacteria,1XWII@135623|Vibrionales	135623|Vibrionales	S	Trans-membrane regulatory protein ToxS	toxS	GO:0005575,GO:0005623,GO:0005886,GO:0007154,GO:0007165,GO:0008150,GO:0009987,GO:0016020,GO:0023052,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0071944	-	ko:K10922	ko05111,map05111	-	-	-	ko00000,ko00001	-	-	-	ToxS
k141_4207_12	78398.KS43_10825	5.28e-72	222.0	COG0622@1|root,COG0622@2|Bacteria,1R3Y7@1224|Proteobacteria,1RY3X@1236|Gammaproteobacteria,1MRD6@122277|Pectobacterium	1236|Gammaproteobacteria	S	Calcineurin-like phosphoesterase superfamily domain	yfcE	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008081,GO:0008150,GO:0009987,GO:0016043,GO:0016787,GO:0016788,GO:0022607,GO:0030145,GO:0042578,GO:0042802,GO:0043167,GO:0043169,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071840	-	ko:K07095	-	-	-	-	ko00000	-	-	-	Metallophos_2
k141_4207_13	1348635.BBJY01000012_gene1124	1.02e-68	210.0	COG2905@1|root,COG2905@2|Bacteria,1MZGY@1224|Proteobacteria,1S86K@1236|Gammaproteobacteria,1XXFK@135623|Vibrionales	135623|Vibrionales	T	COG0517 FOG CBS domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS
k141_4207_14	945550.VISI1226_05561	1.45e-62	193.0	COG0347@1|root,COG0347@2|Bacteria,1RI28@1224|Proteobacteria,1S62Z@1236|Gammaproteobacteria,1XXA8@135623|Vibrionales	135623|Vibrionales	K	Belongs to the P(II) protein family	VV0993	-	-	-	-	-	-	-	-	-	-	-	-
k141_4207_15	672.VV93_v1c09170	4.51e-121	353.0	arCOG03638@1|root,2Z8W3@2|Bacteria,1N2PH@1224|Proteobacteria,1RMI8@1236|Gammaproteobacteria,1XUA3@135623|Vibrionales	135623|Vibrionales	S	Protein of unknown function (DUF1538)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1538
k141_4207_16	1136163.M565_ctg1P0381	1.3e-94	284.0	arCOG03638@1|root,2Z7NN@2|Bacteria,1R3Y6@1224|Proteobacteria,1RTWY@1236|Gammaproteobacteria,1XU34@135623|Vibrionales	135623|Vibrionales	S	Protein of unknown function (DUF1538)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1538
k141_4207_17	945550.VISI1226_05576	2.58e-133	387.0	COG1090@1|root,COG1090@2|Bacteria,1MUB4@1224|Proteobacteria,1RN6A@1236|Gammaproteobacteria,1XSDX@135623|Vibrionales	135623|Vibrionales	S	nucleoside-diphosphate sugar epimerase	yfcH	-	-	ko:K07071	-	-	-	-	ko00000	-	-	-	DUF1731,Epimerase
k141_4207_18	243277.VC_0979	3.15e-127	369.0	COG1028@1|root,COG1028@2|Bacteria,1MUCH@1224|Proteobacteria,1RNAA@1236|Gammaproteobacteria,1XTR2@135623|Vibrionales	135623|Vibrionales	IQ	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	ybbO	-	-	-	-	-	-	-	-	-	-	-	adh_short
k141_4207_19	675814.VIC_000269	2.1e-120	353.0	COG3118@1|root,COG3118@2|Bacteria,1MV0R@1224|Proteobacteria,1RMSQ@1236|Gammaproteobacteria,1XST1@135623|Vibrionales	135623|Vibrionales	O	COG3118 Thioredoxin domain-containing protein	ybbN	-	-	ko:K05838	-	-	-	-	ko00000,ko03110	-	-	-	TPR_19,TPR_20,Thioredoxin
k141_1904_1	1301100.HG529431_gene1834	4.41e-178	506.0	COG2195@1|root,COG2195@2|Bacteria,1TP3A@1239|Firmicutes,248JJ@186801|Clostridia,36EEA@31979|Clostridiaceae	186801|Clostridia	E	Cleaves the N-terminal amino acid of tripeptides	-	-	3.4.11.4	ko:K01258	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
k141_1904_2	1286171.EAL2_c02070	1.07e-122	359.0	COG0030@1|root,COG0030@2|Bacteria,1TP9W@1239|Firmicutes,248RY@186801|Clostridia,25V9W@186806|Eubacteriaceae	186801|Clostridia	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	-	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
k141_1904_3	596315.HMPREF0634_0175	1.84e-72	223.0	COG1658@1|root,COG1658@2|Bacteria,1V3K3@1239|Firmicutes,24I8W@186801|Clostridia,25QDT@186804|Peptostreptococcaceae	186801|Clostridia	J	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step	rnmV	-	3.1.26.8	ko:K05985	-	-	-	-	ko00000,ko01000	-	-	-	DUF4093,Toprim,Toprim_4
k141_1904_4	1123009.AUID01000007_gene638	1.25e-52	181.0	COG0697@1|root,COG0697@2|Bacteria,1V3QH@1239|Firmicutes,24I9P@186801|Clostridia	186801|Clostridia	EG	Permeases of the drug metabolite transporter (DMT)	-	-	-	-	-	-	-	-	-	-	-	-	EamA
k141_1904_6	1226325.HMPREF1548_03725	5.83e-50	186.0	COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,247VG@186801|Clostridia,36DKF@31979|Clostridiaceae	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
k141_1904_7	926561.KB900617_gene1377	3.73e-54	180.0	COG0745@1|root,COG0745@2|Bacteria,1TPZ0@1239|Firmicutes,249IC@186801|Clostridia	186801|Clostridia	T	response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
k141_1904_8	457415.HMPREF1006_01205	1.37e-29	105.0	COG1773@1|root,COG1773@2|Bacteria,3TBI8@508458|Synergistetes	508458|Synergistetes	C	PFAM Rubredoxin-type Fe(Cys)4 protein	-	-	-	-	-	-	-	-	-	-	-	-	Rubredoxin
k141_1904_9	293826.Amet_0136	2.18e-53	186.0	COG3583@1|root,COG3584@1|root,COG3583@2|Bacteria,COG3584@2|Bacteria,1TTIK@1239|Firmicutes,24997@186801|Clostridia,36DTZ@31979|Clostridiaceae	186801|Clostridia	S	G5 domain protein	yabE	-	-	-	-	-	-	-	-	-	-	-	3D,DUF348,G5
k141_1904_10	1121324.CLIT_24c00160	1.01e-44	151.0	2C0BT@1|root,345WP@2|Bacteria,1VYGN@1239|Firmicutes,2536W@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_1904_11	596323.HMPREF0554_0343	3.22e-104	316.0	COG1840@1|root,COG1840@2|Bacteria,3797Q@32066|Fusobacteria	32066|Fusobacteria	P	Bacterial extracellular solute-binding protein	-	-	-	ko:K02012	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	SBP_bac_6
k141_1904_12	536232.CLM_1231	9.66e-191	544.0	COG2271@1|root,COG2271@2|Bacteria,1TS33@1239|Firmicutes,248WJ@186801|Clostridia,36FWX@31979|Clostridiaceae	186801|Clostridia	G	transporter	glpT	-	-	ko:K02445,ko:K07783	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.1.4.3,2.A.1.4.4,2.A.1.4.6	-	-	MFS_1
k141_1904_13	358681.BBR47_02840	6.05e-171	487.0	COG0584@1|root,COG0584@2|Bacteria,1UY23@1239|Firmicutes,4HEAD@91061|Bacilli	91061|Bacilli	C	glycerophosphoryl diester phosphodiesterase	glpQ	-	3.1.3.1,3.1.4.46	ko:K01113,ko:K01126	ko00564,ko00790,ko01100,ko02020,map00564,map00790,map01100,map02020	M00126	R01030,R01470,R04620	RC00017,RC00425	ko00000,ko00001,ko00002,ko01000	-	-	-	GDPD
k141_1904_14	985665.HPL003_16595	3.61e-67	228.0	COG3037@1|root,COG3037@2|Bacteria,1TQK5@1239|Firmicutes,4HBAD@91061|Bacilli,26SPU@186822|Paenibacillaceae	91061|Bacilli	S	PTS system sugar-specific permease component	ulaA	-	-	ko:K03475	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	M00283,M00550	R07671	RC00017,RC03206	ko00000,ko00001,ko00002,ko02000	4.A.7.1	-	-	EIIC-GAT
k141_1904_16	272558.10172832	2.95e-73	258.0	COG1762@1|root,COG3711@1|root,COG1762@2|Bacteria,COG3711@2|Bacteria,1TQT1@1239|Firmicutes,4H9N4@91061|Bacilli,1ZBCM@1386|Bacillus	91061|Bacilli	GKT	COG3711 Transcriptional antiterminator	-	-	2.7.1.194	ko:K02821,ko:K03483	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	M00283,M00550	R07671	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000,ko03000	4.A.7.1	-	-	HTH_11,Mga,PRD,PTS_EIIA_2,PTS_IIB
k141_1904_17	1391646.AVSU01000045_gene1480	2.88e-125	363.0	COG0084@1|root,COG0084@2|Bacteria,1TNY1@1239|Firmicutes,248HE@186801|Clostridia,25QD1@186804|Peptostreptococcaceae	186801|Clostridia	L	TatD related DNase	tatD	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
k141_1904_18	398512.JQKC01000008_gene816	1.26e-109	339.0	COG3501@1|root,COG3501@2|Bacteria,1V043@1239|Firmicutes,248CZ@186801|Clostridia,3WNKD@541000|Ruminococcaceae	186801|Clostridia	S	Rhs element vgr protein	gpP	-	-	-	-	-	-	-	-	-	-	-	Phage_GPD
k141_1904_19	985665.HPL003_27395	3.71e-17	84.3	COG1357@1|root,COG1357@2|Bacteria,1VNCI@1239|Firmicutes,4I7UV@91061|Bacilli,26XPD@186822|Paenibacillaceae	91061|Bacilli	S	PFAM Pentapeptide repeats (8 copies)	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_1904_21	398512.JQKC01000008_gene813	1.17e-34	123.0	2EE7B@1|root,3381W@2|Bacteria,1VAIC@1239|Firmicutes	1239|Firmicutes	S	Domain of unknown function (DUF4280)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4280
k141_1904_23	1163671.JAGI01000002_gene3502	9.1e-27	114.0	COG3501@1|root,COG3501@2|Bacteria,1TSS0@1239|Firmicutes,25BBM@186801|Clostridia,36WKM@31979|Clostridiaceae	186801|Clostridia	S	Rhs element vgr protein	-	-	-	-	-	-	-	-	-	-	-	-	Phage_GPD
k141_1905_1	945543.VIBR0546_02675	2.12e-31	125.0	COG3209@1|root,COG3209@2|Bacteria,1PDT2@1224|Proteobacteria,1TEF8@1236|Gammaproteobacteria,1XZDG@135623|Vibrionales	135623|Vibrionales	M	COG3209 Rhs family protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_3911_1	944479.JQLX01000011_gene782	2.16e-51	182.0	COG1538@1|root,COG1538@2|Bacteria,1PTZ6@1224|Proteobacteria,42RK2@68525|delta/epsilon subdivisions,2WNMB@28221|Deltaproteobacteria,2M70F@213113|Desulfurellales	28221|Deltaproteobacteria	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
k141_3911_2	1121434.AULY01000006_gene569	4.43e-268	785.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MQ0@68525|delta/epsilon subdivisions,2WJ2A@28221|Deltaproteobacteria,2MG2S@213115|Desulfovibrionales	28221|Deltaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k141_3911_4	869213.JCM21142_53	3.44e-27	114.0	COG0845@1|root,COG0845@2|Bacteria,4NIDC@976|Bacteroidetes,47M9U@768503|Cytophagia	976|Bacteroidetes	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3
k141_3911_5	96561.Dole_0361	1.45e-48	178.0	COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,42MEA@68525|delta/epsilon subdivisions,2WIW6@28221|Deltaproteobacteria,2MMMT@213118|Desulfobacterales	28221|Deltaproteobacteria	K	PFAM sigma-54 factor interaction domain-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HTH_8,Sigma54_activat
k141_3571_1	90813.JQMT01000001_gene870	3.94e-27	107.0	COG0564@1|root,COG0564@2|Bacteria,1RDAG@1224|Proteobacteria,1S406@1236|Gammaproteobacteria	1236|Gammaproteobacteria	J	pseudouridine synthase Rlu family protein	Z012_05060	GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	5.4.99.28,5.4.99.29	ko:K06177	-	-	-	-	ko00000,ko01000,ko03009,ko03016	-	-	-	PseudoU_synth_2
k141_3571_2	316275.VSAL_I1143	8.52e-164	465.0	COG1092@1|root,COG1092@2|Bacteria,1PUHQ@1224|Proteobacteria,1RN8N@1236|Gammaproteobacteria,1XTCF@135623|Vibrionales	135623|Vibrionales	J	Belongs to the methyltransferase superfamily	-	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
k141_3571_4	945543.VIBR0546_16036	7.88e-21	84.7	2AWNM@1|root,31NJE@2|Bacteria,1QKA4@1224|Proteobacteria,1TIDN@1236|Gammaproteobacteria,1XYXW@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_3571_5	1348635.BBJY01000014_gene927	1.75e-143	426.0	COG1368@1|root,COG1368@2|Bacteria,1MVCM@1224|Proteobacteria,1RNJ3@1236|Gammaproteobacteria,1XVBR@135623|Vibrionales	135623|Vibrionales	M	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
k141_4230_1	223926.28806430	3.07e-147	435.0	COG0443@1|root,COG0443@2|Bacteria,1MXX7@1224|Proteobacteria,1RQ12@1236|Gammaproteobacteria,1XTFW@135623|Vibrionales	135623|Vibrionales	O	Belongs to the heat shock protein 70 family	-	-	-	-	-	-	-	-	-	-	-	-	HSP70
k141_4230_2	1051646.VITU9109_23180	3.91e-204	595.0	COG0443@1|root,COG0443@2|Bacteria,1MXX7@1224|Proteobacteria,1RP0D@1236|Gammaproteobacteria,1XTBY@135623|Vibrionales	135623|Vibrionales	O	Belongs to the heat shock protein 70 family	-	-	-	-	-	-	-	-	-	-	-	-	DUF3731,HSP70
k141_259_1	1122207.MUS1_00850	2.23e-36	132.0	COG0241@1|root,COG0241@2|Bacteria,1RDGR@1224|Proteobacteria,1S3UD@1236|Gammaproteobacteria,1XJQG@135619|Oceanospirillales	135619|Oceanospirillales	E	D,D-heptose 1,7-bisphosphate phosphatase	gmhB	-	3.1.3.82,3.1.3.83	ko:K03273	ko00540,ko01100,map00540,map01100	M00064	R05647,R09771	RC00017	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hydrolase_like
k141_259_2	477974.Daud_1393	8.4e-204	599.0	COG0507@1|root,COG0507@2|Bacteria,1TPZH@1239|Firmicutes,247R7@186801|Clostridia,26133@186807|Peptococcaceae	186801|Clostridia	L	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity	recD2	-	3.1.11.5	ko:K03581	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AAA_30,HHH_4,HHH_5,UvrD_C_2
k141_4933_2	675815.VOA_000484	1.69e-58	184.0	COG2916@1|root,COG2916@2|Bacteria,1R9YM@1224|Proteobacteria,1S24H@1236|Gammaproteobacteria,1XXBR@135623|Vibrionales	135623|Vibrionales	K	Belongs to the histone-like protein H-NS family	hns	-	-	ko:K03746	-	-	-	-	ko00000,ko03036,ko03400	-	-	-	Histone_HNS
k141_4933_3	672.VV93_v1c12570	2.71e-242	669.0	COG0482@1|root,COG0482@2|Bacteria,1MUT1@1224|Proteobacteria,1RMAK@1236|Gammaproteobacteria,1XU0P@135623|Vibrionales	135623|Vibrionales	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	GO:0001510,GO:0002097,GO:0002098,GO:0002143,GO:0003674,GO:0003824,GO:0004808,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
k141_4933_4	55601.VANGNB10_cI1061c	2.16e-107	313.0	COG2915@1|root,COG2915@2|Bacteria,1RI8B@1224|Proteobacteria,1RPCC@1236|Gammaproteobacteria,1XT1A@135623|Vibrionales	135623|Vibrionales	S	High frequency lysogenization protein HflD homolog	hflD	-	-	ko:K07153	-	-	-	-	ko00000	-	-	-	DUF489
k141_4933_5	29495.EA26_15840	4.42e-292	801.0	COG0015@1|root,COG0015@2|Bacteria,1MV4B@1224|Proteobacteria,1RN93@1236|Gammaproteobacteria,1XT6I@135623|Vibrionales	135623|Vibrionales	F	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	purB	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ASL_C,Lyase_1
k141_4933_6	1219065.VPR01S_03_00260	1.51e-148	424.0	COG0501@1|root,COG0501@2|Bacteria,1MUV4@1224|Proteobacteria,1RMN0@1236|Gammaproteobacteria,1XSVQ@135623|Vibrionales	135623|Vibrionales	O	Belongs to the peptidase M48B family	htpX	GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0050896	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	Peptidase_M48
k141_4933_8	1219076.N646_0167	1.4e-116	338.0	COG0132@1|root,COG0132@2|Bacteria,1RDRK@1224|Proteobacteria,1RSHS@1236|Gammaproteobacteria,1XSF9@135623|Vibrionales	135623|Vibrionales	H	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring	bioD	GO:0003674,GO:0003824,GO:0004141,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0017144,GO:0018130,GO:0019752,GO:0032787,GO:0034641,GO:0042364,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.3.3	ko:K01935	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03182	RC00868	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_26
k141_4933_9	945550.VISI1226_18261	7.95e-205	572.0	COG0502@1|root,COG0502@2|Bacteria,1MVFF@1224|Proteobacteria,1RMEQ@1236|Gammaproteobacteria,1XTAY@135623|Vibrionales	135623|Vibrionales	H	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism	bioB	GO:0003674,GO:0003824,GO:0004076,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0017144,GO:0018130,GO:0019752,GO:0032787,GO:0034641,GO:0042364,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.8.1.6	ko:K01012	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R01078	RC00441	ko00000,ko00001,ko00002,ko01000	-	-	-	BATS,Radical_SAM
k141_4933_11	1280001.BAOA01000027_gene4822	2.87e-275	757.0	COG0172@1|root,COG0172@2|Bacteria,1MUJF@1224|Proteobacteria,1RNAQ@1236|Gammaproteobacteria,1XUNW@135623|Vibrionales	135623|Vibrionales	J	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)	serS	GO:0003674,GO:0003824,GO:0004812,GO:0004828,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006434,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
k141_4933_12	1219065.VPR01S_02_02930	1.29e-255	709.0	COG2256@1|root,COG2256@2|Bacteria,1MUVS@1224|Proteobacteria,1RPBY@1236|Gammaproteobacteria,1XUU2@135623|Vibrionales	135623|Vibrionales	L	COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase	rarA	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA,AAA_assoc_2,MgsA_C
k141_4933_13	55601.VANGNB10_cI1733c	1.26e-87	263.0	COG2834@1|root,COG2834@2|Bacteria,1PXDV@1224|Proteobacteria,1S9FW@1236|Gammaproteobacteria,1XU2P@135623|Vibrionales	135623|Vibrionales	M	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)	lolA	GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705	-	ko:K03634	-	-	-	-	ko00000	-	-	-	LolA
k141_4933_14	675816.VIA_003460	3.7e-65	206.0	COG3012@1|root,COG3012@2|Bacteria,1QN8B@1224|Proteobacteria,1T25E@1236|Gammaproteobacteria,1XWAD@135623|Vibrionales	135623|Vibrionales	S	metal-binding protein related to the C-terminal domain of SecA	-	-	-	ko:K07039	-	-	-	-	ko00000	-	-	-	SEC-C,UPF0149
k141_4933_15	675815.VOA_000507	1.15e-153	440.0	COG0042@1|root,COG0042@2|Bacteria,1MUSM@1224|Proteobacteria,1RMMM@1236|Gammaproteobacteria,1XTYF@135623|Vibrionales	135623|Vibrionales	J	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U16 in tRNAs	dusC	-	-	ko:K05541	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Dus
k141_4933_16	990285.RGCCGE502_10821	1.43e-19	98.2	COG2199@1|root,COG2199@2|Bacteria,1N1BS@1224|Proteobacteria,2UQ0F@28211|Alphaproteobacteria,4B94P@82115|Rhizobiaceae	28211|Alphaproteobacteria	T	GGDEF domain	-	-	2.7.7.65	ko:K13590	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000	-	-	-	GGDEF
k141_4933_17	945550.VISI1226_17775	5.26e-153	434.0	COG1101@1|root,COG1101@2|Bacteria,1MVDM@1224|Proteobacteria,1RSNT@1236|Gammaproteobacteria,1XUIF@135623|Vibrionales	135623|Vibrionales	S	abc transporter atp-binding protein	-	-	-	ko:K05833	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_tran
k141_4933_18	1280001.BAOA01000020_gene391	6.6e-79	244.0	COG4120@1|root,COG4120@2|Bacteria,1MXGE@1224|Proteobacteria,1RY3E@1236|Gammaproteobacteria,1XUY5@135623|Vibrionales	135623|Vibrionales	S	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K05832	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	BPD_transp_2
k141_2487_1	1304885.AUEY01000001_gene3192	3.7e-71	215.0	COG0607@1|root,COG0607@2|Bacteria,1RE94@1224|Proteobacteria,42RGF@68525|delta/epsilon subdivisions,2WNWK@28221|Deltaproteobacteria,2MK0V@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
k141_2487_2	338963.Pcar_1369	2.2e-113	349.0	COG2108@1|root,COG2108@2|Bacteria,1MY1Y@1224|Proteobacteria,42MIQ@68525|delta/epsilon subdivisions,2WJD2@28221|Deltaproteobacteria,43TNW@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	4Fe-4S single cluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Fer4_14,Radical_SAM
k141_1906_1	1187848.AJYQ01000066_gene3582	3.83e-195	587.0	COG3096@1|root,COG3096@2|Bacteria,1MUWM@1224|Proteobacteria,1RPFF@1236|Gammaproteobacteria,1XUHB@135623|Vibrionales	135623|Vibrionales	D	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division	mukB	GO:0007059,GO:0008150,GO:0009987	-	ko:K03632	-	-	-	-	ko00000,ko03036	-	-	-	MukB,MukB_hinge,SbcCD_C
k141_3912_1	1278307.KB906972_gene1145	4.34e-27	110.0	2AVG0@1|root,31M86@2|Bacteria,1QJ2Y@1224|Proteobacteria,1TH0P@1236|Gammaproteobacteria,2QIWH@267894|Psychromonadaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_4621_1	1121405.dsmv_3220	3.64e-52	177.0	COG0263@1|root,COG0263@2|Bacteria,1MUBG@1224|Proteobacteria,42NEA@68525|delta/epsilon subdivisions,2WIVS@28221|Deltaproteobacteria,2MHN5@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate	proB	GO:0003674,GO:0003824,GO:0004349,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0018130,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.2.11	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	M00015	R00239	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_3198	AA_kinase,PUA
k141_4621_2	96561.Dole_0090	5.58e-170	489.0	COG0014@1|root,COG0014@2|Bacteria,1MUGJ@1224|Proteobacteria,42ME0@68525|delta/epsilon subdivisions,2WJB8@28221|Deltaproteobacteria,2MHR6@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate	proA	GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114	1.2.1.41	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	M00015	R03313	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
k141_4621_3	269799.Gmet_3200	1.19e-40	144.0	COG1057@1|root,COG1057@2|Bacteria,1RD0J@1224|Proteobacteria,42SD9@68525|delta/epsilon subdivisions,2WPPN@28221|Deltaproteobacteria,43TVZ@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_3200	CTP_transf_like
k141_4621_4	667014.Thein_1013	2.44e-27	106.0	COG0799@1|root,COG0799@2|Bacteria,2GHZ7@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	S	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation	rsfS	-	-	ko:K09710	-	-	-	-	ko00000,ko03009	-	-	-	RsfS
k141_4621_5	1121396.KB893035_gene3592	5.52e-193	555.0	COG0696@1|root,COG0696@2|Bacteria,1MUQ1@1224|Proteobacteria,42N6C@68525|delta/epsilon subdivisions,2WJ66@28221|Deltaproteobacteria,2MIE2@213118|Desulfobacterales	28221|Deltaproteobacteria	G	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate	gpmI	-	5.4.2.12	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,Phosphodiest,iPGM_N
k141_4621_6	1304885.AUEY01000051_gene1493	3.27e-44	151.0	2ARUS@1|root,31H6C@2|Bacteria,1RFAK@1224|Proteobacteria,42RXP@68525|delta/epsilon subdivisions,2WNXF@28221|Deltaproteobacteria,2MK37@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Type I restriction enzyme R protein N terminus (HSDR_N)	-	-	-	-	-	-	-	-	-	-	-	-	HSDR_N_2
k141_4621_7	1304885.AUEY01000059_gene2407	7.41e-99	293.0	COG1413@1|root,COG1413@2|Bacteria,1RBEY@1224|Proteobacteria,42QE1@68525|delta/epsilon subdivisions,2WKQU@28221|Deltaproteobacteria,2MJEC@213118|Desulfobacterales	28221|Deltaproteobacteria	C	lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	zf-ribbon_3
k141_4934_2	1236542.BALM01000035_gene4245	1.14e-29	120.0	COG1835@1|root,COG1835@2|Bacteria,1MV2W@1224|Proteobacteria,1RQS2@1236|Gammaproteobacteria,2QBUB@267890|Shewanellaceae	1236|Gammaproteobacteria	I	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
k141_260_1	1408445.JHXP01000042_gene3148	4.08e-47	159.0	COG1961@1|root,COG1961@2|Bacteria,1RA0V@1224|Proteobacteria,1RPSK@1236|Gammaproteobacteria,1JGHE@118969|Legionellales	118969|Legionellales	L	Resolvase, N terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Resolvase
k141_260_2	1391646.AVSU01000063_gene3372	1.91e-13	77.0	COG2522@1|root,COG2522@2|Bacteria,1V00D@1239|Firmicutes,24H1A@186801|Clostridia,25SAX@186804|Peptostreptococcaceae	186801|Clostridia	O	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_2488_1	871968.DESME_14180	4.36e-07	57.4	COG1305@1|root,COG2720@1|root,COG1305@2|Bacteria,COG2720@2|Bacteria	2|Bacteria	V	VanW like protein	-	-	-	-	-	-	-	-	-	-	-	-	CW_binding_2,G5,PG_binding_4,Transglut_core,VanW
k141_2488_2	1121935.AQXX01000041_gene4651	7.43e-26	108.0	COG2931@1|root,COG4733@1|root,COG2931@2|Bacteria,COG4733@2|Bacteria,1PPUE@1224|Proteobacteria,1RQKW@1236|Gammaproteobacteria,1XR4B@135619|Oceanospirillales	135619|Oceanospirillales	Q	Haemolysin-type calcium-binding repeat (2 copies)	-	-	-	-	-	-	-	-	-	-	-	-	HemolysinCabind
k141_261_1	445972.ANACOL_03938	2.2e-26	106.0	COG2025@1|root,COG2025@2|Bacteria,1TPC8@1239|Firmicutes,247NF@186801|Clostridia,3WHXG@541000|Ruminococcaceae	186801|Clostridia	C	Electron transfer flavoprotein domain	etfA	-	-	ko:K03522	-	-	-	-	ko00000,ko04147	-	-	-	ETF,ETF_alpha
k141_261_2	1121289.JHVL01000008_gene1240	2.61e-88	273.0	COG0277@1|root,COG0277@2|Bacteria,1TPBC@1239|Firmicutes,24A99@186801|Clostridia,36DRC@31979|Clostridiaceae	186801|Clostridia	C	FAD linked oxidase domain protein	glcD1	-	1.1.3.15	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
k141_4231_2	748280.NH8B_0754	1.38e-28	115.0	COG0288@1|root,COG0288@2|Bacteria,1RKKR@1224|Proteobacteria,2VTB7@28216|Betaproteobacteria,2KSCZ@206351|Neisseriales	206351|Neisseriales	P	Carbonic anhydrase	-	-	4.2.1.1	ko:K01673	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Pro_CA
k141_3574_1	96561.Dole_2586	1.54e-185	543.0	COG1674@1|root,COG1674@2|Bacteria,1MVPI@1224|Proteobacteria,42N4X@68525|delta/epsilon subdivisions,2WIPR@28221|Deltaproteobacteria,2MI69@213118|Desulfobacterales	28221|Deltaproteobacteria	D	DNA segregation ATPase, FtsK SpoIIIE family	ftsK	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
k141_4622_1	675813.VIB_001317	3.22e-58	194.0	2CG2X@1|root,2Z7NT@2|Bacteria,1MW33@1224|Proteobacteria,1RQZI@1236|Gammaproteobacteria,1XSII@135623|Vibrionales	135623|Vibrionales	-	-	VP1614	-	-	-	-	-	-	-	-	-	-	-	-
k141_4622_2	55601.VANGNB10_cI1246	2.03e-95	290.0	COG1080@1|root,COG1080@2|Bacteria,1QUXJ@1224|Proteobacteria,1T250@1236|Gammaproteobacteria,1XU1A@135623|Vibrionales	135623|Vibrionales	G	PEP-utilising enzyme, TIM barrel domain	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers_C
k141_4622_3	1238450.VIBNISOn1_1720110	6.21e-78	235.0	COG1666@1|root,COG1666@2|Bacteria,1RDTF@1224|Proteobacteria,1S3RU@1236|Gammaproteobacteria,1XX34@135623|Vibrionales	135623|Vibrionales	S	Belongs to the UPF0234 family	yajQ	-	-	ko:K09767	-	-	-	-	ko00000	-	-	-	DUF520
k141_3576_1	1304885.AUEY01000052_gene1561	8.49e-81	244.0	COG1100@1|root,COG1100@2|Bacteria,1R6NS@1224|Proteobacteria,42NIX@68525|delta/epsilon subdivisions,2WJ44@28221|Deltaproteobacteria,2MI9K@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Gtr1/RagA G protein conserved region	mglA	GO:0008150,GO:0032879,GO:0032880,GO:0050789,GO:0065007	-	ko:K06883	-	-	-	-	ko00000	-	-	-	Arf,Ras
k141_3576_2	1121403.AUCV01000003_gene1793	7.71e-08	58.5	2CFWZ@1|root,32ZKU@2|Bacteria,1NDUW@1224|Proteobacteria,42W37@68525|delta/epsilon subdivisions,2WRCI@28221|Deltaproteobacteria,2MKYY@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	ko:K08086	-	-	-	-	ko00000	-	-	-	-
k141_4936_1	1187848.AJYQ01000088_gene2901	3.83e-157	454.0	COG0477@1|root,COG2814@2|Bacteria,1R91P@1224|Proteobacteria,1RMVM@1236|Gammaproteobacteria,1XV55@135623|Vibrionales	135623|Vibrionales	EGP	COG0477 Permeases of the major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
k141_4936_2	55601.VANGNB10_cII0053	9.4e-117	340.0	COG2188@1|root,COG2188@2|Bacteria,1R4PN@1224|Proteobacteria,1RQ87@1236|Gammaproteobacteria,1XU8B@135623|Vibrionales	135623|Vibrionales	K	COG2188 Transcriptional regulators	-	-	-	-	-	-	-	-	-	-	-	-	GntR,UTRA
k141_4936_3	223926.28808520	1.75e-88	270.0	COG1840@1|root,COG1840@2|Bacteria,1Q13Q@1224|Proteobacteria,1RWV9@1236|Gammaproteobacteria,1XVMA@135623|Vibrionales	135623|Vibrionales	P	COG1840 ABC-type Fe3 transport system, periplasmic component	-	-	-	ko:K02055	ko02024,map02024	M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11	-	-	SBP_bac_6
k141_2489_1	1278307.KB906993_gene3277	1.28e-80	244.0	COG0622@1|root,COG0622@2|Bacteria,1R3Y7@1224|Proteobacteria,1RY3X@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Phosphoesterase	yfcE	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008081,GO:0008150,GO:0009987,GO:0016043,GO:0016787,GO:0016788,GO:0022607,GO:0030145,GO:0042578,GO:0042802,GO:0043167,GO:0043169,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071840	-	ko:K07095	-	-	-	-	ko00000	-	-	-	Metallophos_2
k141_976_3	1304885.AUEY01000052_gene1558	2.53e-22	97.8	COG2770@1|root,COG2770@2|Bacteria,1NDB2@1224|Proteobacteria,42WRP@68525|delta/epsilon subdivisions,2WSBD@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP
k141_4080_2	345073.VC395_2547	2.26e-90	270.0	COG3150@1|root,COG3150@2|Bacteria,1MVJF@1224|Proteobacteria,1S5WF@1236|Gammaproteobacteria,1XTCB@135623|Vibrionales	135623|Vibrionales	S	esterase	yqiA	-	-	ko:K07000	-	-	-	-	ko00000	-	-	-	UPF0227
k141_4080_3	243277.VC_2433	4.94e-135	389.0	COG1409@1|root,COG1409@2|Bacteria,1MWKX@1224|Proteobacteria,1RPA7@1236|Gammaproteobacteria,1XTA7@135623|Vibrionales	135623|Vibrionales	S	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes	cpdA	-	3.1.4.53	ko:K03651	ko00230,ko02025,map00230,map02025	-	R00191	RC00296	ko00000,ko00001,ko01000	-	-	-	Metallophos
k141_4080_4	1219065.VPR01S_21_00560	1.38e-76	231.0	COG3151@1|root,COG3151@2|Bacteria,1RA4E@1224|Proteobacteria,1SA3I@1236|Gammaproteobacteria,1XXGE@135623|Vibrionales	135623|Vibrionales	S	protein conserved in bacteria	-	-	-	ko:K09920	-	-	-	-	ko00000	-	-	-	DUF1249
k141_4080_5	243277.VC_2435	7.38e-105	307.0	COG0494@1|root,COG0494@2|Bacteria,1RDMW@1224|Proteobacteria,1RPZV@1236|Gammaproteobacteria,1XUUC@135623|Vibrionales	135623|Vibrionales	L	COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes	nudF	-	3.6.1.13	ko:K01515	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
k141_4080_6	55601.VANGNB10_cI2200	1.54e-198	563.0	COG1538@1|root,COG1538@2|Bacteria,1MWCJ@1224|Proteobacteria,1RQQV@1236|Gammaproteobacteria,1XT4C@135623|Vibrionales	135623|Vibrionales	MU	COG1538 Outer membrane protein	tolC	GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705	-	ko:K12340	ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133	M00325,M00326,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko02044	1.B.17,2.A.6.2	-	-	OEP
k141_2974_2	397288.C806_03780	3.72e-41	152.0	COG1897@1|root,COG1897@2|Bacteria,1TQVR@1239|Firmicutes,247NP@186801|Clostridia,27J4B@186928|unclassified Lachnospiraceae	186801|Clostridia	E	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine	metAA	-	2.3.1.46	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	M00017	R01777	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS11970	HTS
k141_2974_3	1121324.CLIT_23c02390	2.92e-178	511.0	COG2873@1|root,COG2873@2|Bacteria,1VYCY@1239|Firmicutes,247XK@186801|Clostridia,25QKY@186804|Peptostreptococcaceae	186801|Clostridia	E	O-acetylhomoserine	metY	-	2.5.1.49	ko:K01740	ko00270,ko01100,map00270,map01100	-	R01287,R04859	RC00020,RC02821,RC02848	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
k141_2974_4	931626.Awo_c02820	3.75e-77	251.0	COG0527@1|root,COG0527@2|Bacteria,1TPQJ@1239|Firmicutes,24811@186801|Clostridia,25V9Z@186806|Eubacteriaceae	186801|Clostridia	E	Belongs to the aspartokinase family	lysC	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT,ACT_7
k141_2974_5	1231057.AMGD01000017_gene1345	2.23e-64	219.0	COG0460@1|root,COG0460@2|Bacteria,1TQ2H@1239|Firmicutes,4HBAP@91061|Bacilli,26DDX@186818|Planococcaceae	91061|Bacilli	E	Homoserine dehydrogenase	hom	-	1.1.1.3	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00017,M00018	R01773,R01775	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS06610	ACT,Homoserine_dh,NAD_binding_3
k141_2974_6	469616.FMAG_00747	1.02e-83	260.0	COG0685@1|root,COG0685@2|Bacteria,3787V@32066|Fusobacteria	32066|Fusobacteria	C	Psort location Cytoplasmic, score	metF	-	1.5.1.20	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	M00377	R01224,R07168	RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR
k141_2974_7	1160721.RBI_I01350	2.77e-30	118.0	COG1410@1|root,COG1410@2|Bacteria,1V7JJ@1239|Firmicutes,24AE1@186801|Clostridia,3WJ7R@541000|Ruminococcaceae	186801|Clostridia	E	Vitamin B12 dependent methionine synthase activation	metH2	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	Met_synt_B12
k141_2974_8	1443122.Z958_02965	6.07e-133	378.0	COG2452@1|root,COG2452@2|Bacteria,1TQNJ@1239|Firmicutes,24B79@186801|Clostridia,36GX6@31979|Clostridiaceae	186801|Clostridia	L	MerR HTH family regulatory protein	-	-	-	ko:K07450	-	-	-	-	ko00000	-	-	-	MerR,MerR_1,Resolvase
k141_2974_9	1410653.JHVC01000014_gene3383	4.17e-185	525.0	COG0675@1|root,COG0675@2|Bacteria,1TRNY@1239|Firmicutes,247T1@186801|Clostridia,36E4A@31979|Clostridiaceae	186801|Clostridia	L	Transposase	-	-	-	ko:K07496	-	-	-	-	ko00000	-	-	-	HTH_OrfB_IS605,OrfB_IS605,OrfB_Zn_ribbon
k141_2974_10	545697.HMPREF0216_02149	2.81e-255	735.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,1TPYV@1239|Firmicutes,248JB@186801|Clostridia,36DUH@31979|Clostridiaceae	186801|Clostridia	E	Methionine synthase	metH	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Pterin_bind,S-methyl_trans
k141_2974_11	521045.Kole_1675	2.41e-21	97.8	COG5061@1|root,COG5061@2|Bacteria,2GDZC@200918|Thermotogae	200918|Thermotogae	OU	Protein of unknown function (DUF3307)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3307
k141_2974_13	240302.BN982_01688	4.45e-17	80.5	COG1670@1|root,COG1670@2|Bacteria,1V7SS@1239|Firmicutes,4HJGC@91061|Bacilli	91061|Bacilli	J	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases	-	-	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_3
k141_2974_17	1121324.CLIT_14c00060	0.0	897.0	COG1061@1|root,COG3886@1|root,COG1061@2|Bacteria,COG3886@2|Bacteria,1TQ62@1239|Firmicutes,249TK@186801|Clostridia	186801|Clostridia	L	helicase	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,PLDc_2,ResIII
k141_2974_18	386415.NT01CX_0322	9.55e-07	50.8	COG4997@1|root,COG4997@2|Bacteria,1VEG6@1239|Firmicutes,24QRF@186801|Clostridia,36KRV@31979|Clostridiaceae	186801|Clostridia	S	phosphoribosyl-ATP pyrophosphohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	DUF429,MazG-like
k141_2974_19	86416.Clopa_3880	4.38e-54	172.0	COG0537@1|root,COG0537@2|Bacteria,1V5CH@1239|Firmicutes,25CUE@186801|Clostridia	186801|Clostridia	FG	Scavenger mRNA decapping enzyme C-term binding	-	-	2.7.7.53	ko:K19710	ko00230,map00230	-	R00126,R01618	RC00002,RC02753,RC02795	ko00000,ko00001,ko01000	-	-	-	HIT
k141_2974_20	1121324.CLIT_14c00060	4.63e-221	648.0	COG1061@1|root,COG3886@1|root,COG1061@2|Bacteria,COG3886@2|Bacteria,1TQ62@1239|Firmicutes,249TK@186801|Clostridia	186801|Clostridia	L	helicase	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,PLDc_2,ResIII
k141_2974_21	293826.Amet_1575	4.5e-98	322.0	COG0840@1|root,COG0840@2|Bacteria,1TP5A@1239|Firmicutes,247S3@186801|Clostridia,36EQK@31979|Clostridiaceae	186801|Clostridia	NT	chemotaxis	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	Cache_3-Cache_2,HAMP,MCPsignal,dCache_1
k141_2974_23	445973.CLOBAR_01508	1.77e-69	211.0	COG0346@1|root,COG0346@2|Bacteria,1V6K3@1239|Firmicutes,24J94@186801|Clostridia,25RFW@186804|Peptostreptococcaceae	186801|Clostridia	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	gloA	-	4.4.1.5	ko:K01759	ko00620,map00620	-	R02530	RC00004,RC00740	ko00000,ko00001,ko01000	-	-	-	Glyoxalase
k141_1656_1	243365.CV_0799	9.29e-84	259.0	COG1917@1|root,COG2207@1|root,COG1917@2|Bacteria,COG2207@2|Bacteria,1P1FH@1224|Proteobacteria,2WGH0@28216|Betaproteobacteria	28216|Betaproteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
k141_978_1	1265505.ATUG01000001_gene2956	6.03e-138	395.0	COG0395@1|root,COG0395@2|Bacteria,1MUWS@1224|Proteobacteria,42P8C@68525|delta/epsilon subdivisions,2WJ3R@28221|Deltaproteobacteria,2MN25@213118|Desulfobacterales	28221|Deltaproteobacteria	G	Binding-protein-dependent transport system inner membrane component	ugpE	-	-	ko:K05815	ko02010,map02010	M00198	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.3	-	-	BPD_transp_1
k141_5339_2	1123053.AUDG01000059_gene409	1.28e-19	81.3	2EJUI@1|root,33DJ6@2|Bacteria,1NI17@1224|Proteobacteria,1SGQW@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_5339_4	675816.VIA_000507	1.42e-158	452.0	COG0340@1|root,COG1654@1|root,COG0340@2|Bacteria,COG1654@2|Bacteria,1MWCC@1224|Proteobacteria,1RNGC@1236|Gammaproteobacteria,1XUFE@135623|Vibrionales	135623|Vibrionales	H	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon	birA	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_C,BPL_LplA_LipB,HTH_11
k141_5339_5	945543.VIBR0546_14652	3.87e-154	443.0	COG0812@1|root,COG0812@2|Bacteria,1MXDH@1224|Proteobacteria,1RNXK@1236|Gammaproteobacteria,1XTDX@135623|Vibrionales	135623|Vibrionales	M	Cell wall formation	murB	GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008762,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0055114,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	-	FAD_binding_4,MurB_C
k141_5339_6	1219076.N646_2007	3.04e-26	102.0	COG3153@1|root,COG3153@2|Bacteria,1QUGJ@1224|Proteobacteria,1T1YA@1236|Gammaproteobacteria,1XYFN@135623|Vibrionales	135623|Vibrionales	S	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_10,Acetyltransf_7
k141_5339_7	55601.VANGNB10_cI0198c	1.71e-240	670.0	COG1502@1|root,COG1502@2|Bacteria,1MVPU@1224|Proteobacteria,1RN1V@1236|Gammaproteobacteria,1XT62@135623|Vibrionales	135623|Vibrionales	I	COG1502 Phosphatidylserine phosphatidylglycerophosphate cardiolipi n synthases and related enzymes	pssA	-	2.7.8.8	ko:K00998	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	M00093	R01800	RC00002,RC00017,RC02795	ko00000,ko00001,ko00002,ko01000	-	-	-	PLDc_2,Regulator_TrmB
k141_3047_1	1121904.ARBP01000025_gene6086	1.56e-34	139.0	COG2273@1|root,COG2273@2|Bacteria	2|Bacteria	G	xyloglucan:xyloglucosyl transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,CBM_2,CBM_4_9,CBM_6,CHB_HEX_C_1,DUF1349,F5_F8_type_C,Glyco_hydro_16,Glyco_hydro_76,Glyco_hydro_81,Laminin_G_3,RicinB_lectin_2,fn3
k141_3048_1	350688.Clos_2826	2.86e-77	257.0	COG0834@1|root,COG4191@1|root,COG0834@2|Bacteria,COG4191@2|Bacteria,1TSVK@1239|Firmicutes,24CCA@186801|Clostridia,36HB1@31979|Clostridiaceae	186801|Clostridia	T	Bacterial periplasmic substrate-binding proteins	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	HATPase_c,HisKA,PAS_9,SBP_bac_3
k141_3051_1	1304885.AUEY01000012_gene1792	2.13e-86	274.0	COG0446@1|root,COG1902@1|root,COG0446@2|Bacteria,COG1902@2|Bacteria,1MVE0@1224|Proteobacteria,42PDA@68525|delta/epsilon subdivisions,2WK05@28221|Deltaproteobacteria,2MHS3@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM NADH flavin oxidoreductase NADH oxidase	-	-	1.3.1.34	ko:K00219	-	-	-	-	ko00000,ko01000	-	-	-	Oxidored_FMN,Pyr_redox_2
k141_3052_2	748449.Halha_1482	8.26e-139	398.0	COG2801@1|root,COG2801@2|Bacteria,1TPEH@1239|Firmicutes,24DNX@186801|Clostridia,3WB69@53433|Halanaerobiales	186801|Clostridia	L	PFAM Integrase catalytic region	-	-	-	-	-	-	-	-	-	-	-	-	HTH_21,rve
k141_3052_3	1121289.JHVL01000075_gene1050	4.91e-48	154.0	COG2963@1|root,COG2963@2|Bacteria,1V9ZX@1239|Firmicutes,24P3X@186801|Clostridia,36MBA@31979|Clostridiaceae	186801|Clostridia	L	PFAM transposase IS3 IS911 family protein	-	-	-	ko:K07483	-	-	-	-	ko00000	-	-	-	HTH_Tnp_1
k141_3334_1	1121405.dsmv_1703	3.61e-243	705.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,42NAV@68525|delta/epsilon subdivisions,2WJ3W@28221|Deltaproteobacteria,2MIIB@213118|Desulfobacterales	28221|Deltaproteobacteria	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
k141_3334_2	1304885.AUEY01000021_gene3466	3.23e-11	59.3	2EJAZ@1|root,3356X@2|Bacteria,1NFZK@1224|Proteobacteria,42V0Q@68525|delta/epsilon subdivisions,2WS7N@28221|Deltaproteobacteria,2MMC0@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_3334_3	1304885.AUEY01000033_gene1912	1.1e-146	429.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42PGC@68525|delta/epsilon subdivisions,2WKHK@28221|Deltaproteobacteria,2MJ4J@213118|Desulfobacterales	28221|Deltaproteobacteria	T	ATP-binding region ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	FHA,HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Response_reg,dCache_3
k141_3334_4	1121035.AUCH01000028_gene3255	6.59e-14	70.9	COG3437@1|root,COG3437@2|Bacteria,1RDJ3@1224|Proteobacteria,2VR5G@28216|Betaproteobacteria,2KWE0@206389|Rhodocyclales	206389|Rhodocyclales	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
k141_3053_1	1033732.CAHI01000003_gene2404	0.000493	48.1	COG2204@1|root,COG2204@2|Bacteria,4NE89@976|Bacteroidetes,2FMPG@200643|Bacteroidia,22UX1@171550|Rikenellaceae	976|Bacteroidetes	T	Sigma-54 interaction domain	ntrX	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
k141_3054_2	55601.VANGNB10_cII0825	9.68e-188	527.0	COG1052@1|root,COG1052@2|Bacteria,1MVSS@1224|Proteobacteria,1RMWR@1236|Gammaproteobacteria,1XT4W@135623|Vibrionales	135623|Vibrionales	C	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family	ldhA	-	1.1.1.28	ko:K03778	ko00620,ko01120,map00620,map01120	-	R00704	RC00044	ko00000,ko00001,ko01000	-	-	-	2-Hacid_dh,2-Hacid_dh_C
k141_3054_3	1348635.BBJY01000003_gene3788	5.84e-90	280.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,1MU1Q@1224|Proteobacteria,1RMPS@1236|Gammaproteobacteria,1XTWB@135623|Vibrionales	135623|Vibrionales	H	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	Carb_kinase,YjeF_N
k141_3336_1	158190.SpiGrapes_1527	5.02e-66	218.0	COG1129@1|root,COG1129@2|Bacteria,2J5C4@203691|Spirochaetes	203691|Spirochaetes	P	ABC-type sugar transport system, ATPase component	-	-	3.6.3.17	ko:K02056	-	M00221	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.2	-	-	ABC_tran
k141_3056_1	237368.SCABRO_00095	2.28e-72	227.0	COG1583@1|root,COG1583@2|Bacteria,2J4BE@203682|Planctomycetes	203682|Planctomycetes	L	CRISPR associated protein Cas6	-	-	-	-	-	-	-	-	-	-	-	-	Cas_Cas6
k141_3337_1	1280001.BAOA01000020_gene369	1.1e-259	729.0	COG1882@1|root,COG1882@2|Bacteria,1MWBF@1224|Proteobacteria,1SM64@1236|Gammaproteobacteria,1XT8B@135623|Vibrionales	135623|Vibrionales	C	Pyruvate formate lyase-like	-	-	2.3.1.54	ko:K00656	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	-	R00212,R06987	RC00004,RC01181,RC02742,RC02833	ko00000,ko00001,ko01000	-	-	-	Gly_radical,PFL-like
k141_3338_1	404380.Gbem_3163	2.33e-116	346.0	COG0031@1|root,COG0031@2|Bacteria,1MUBE@1224|Proteobacteria,42M6M@68525|delta/epsilon subdivisions,2WIQM@28221|Deltaproteobacteria	28221|Deltaproteobacteria	EJ	PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit	cysM	-	2.5.1.47,6.1.1.16	ko:K01738,ko:K01883,ko:K12339	ko00270,ko00920,ko00970,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map00970,map01100,map01110,map01120,map01130,map01200,map01230	M00021,M00359,M00360	R00897,R03132,R03601,R03650,R04859	RC00020,RC00055,RC00523,RC02814,RC02821,RC02876	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,PALP,tRNA-synt_1e
k141_3057_2	1187848.AJYQ01000127_gene615	1.03e-172	490.0	COG2813@1|root,COG2813@2|Bacteria,1MXE9@1224|Proteobacteria,1RQCH@1236|Gammaproteobacteria,1XUIH@135623|Vibrionales	135623|Vibrionales	J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle	rsmC	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0008990,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0052914,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.172	ko:K00564	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	MTS,MTS_N
k141_3057_3	1348635.BBJY01000008_gene1796	1e-257	711.0	COG0004@1|root,COG0004@2|Bacteria,1NR9F@1224|Proteobacteria,1RNKF@1236|Gammaproteobacteria,1XU86@135623|Vibrionales	135623|Vibrionales	P	COG0004 Ammonia permease	amtB	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
k141_3340_1	198628.Dda3937_03955	6.91e-16	84.3	COG4913@1|root,COG4913@2|Bacteria,1N16Z@1224|Proteobacteria,1RPTX@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	AAA_29,SbcCD_C
k141_3341_1	1219076.N646_1157	5.42e-28	104.0	COG3092@1|root,COG3092@2|Bacteria,1N172@1224|Proteobacteria,1S495@1236|Gammaproteobacteria,1XWYB@135623|Vibrionales	135623|Vibrionales	S	UPF0208 membrane protein	-	-	-	ko:K09899	-	-	-	-	ko00000	-	-	-	DUF412
k141_3341_2	1348635.BBJY01000004_gene2959	1.84e-186	523.0	COG2984@1|root,COG2984@2|Bacteria,1MW5D@1224|Proteobacteria,1RR1N@1236|Gammaproteobacteria,1XSVW@135623|Vibrionales	135623|Vibrionales	S	ABC transporter substrate-binding protein	-	-	-	ko:K01989	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_sub_bind
k141_3058_1	1219077.VAZ01S_070_00350	1.05e-62	197.0	2ANPA@1|root,31DNS@2|Bacteria,1RHTE@1224|Proteobacteria,1S2Z7@1236|Gammaproteobacteria,1XWZY@135623|Vibrionales	135623|Vibrionales	S	Protein of unknown function (DUF3833)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3833
k141_3059_1	1238450.VIBNISOn1_1560018	1.5e-34	121.0	COG0640@1|root,COG0640@2|Bacteria,1N72Q@1224|Proteobacteria,1SCH5@1236|Gammaproteobacteria,1XYDG@135623|Vibrionales	135623|Vibrionales	K	Transcriptional regulator ArsR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
k141_3061_1	242619.PG_1138	4.81e-26	108.0	COG0399@1|root,COG0399@2|Bacteria,4NEBI@976|Bacteroidetes,2FPAJ@200643|Bacteroidia,22WTH@171551|Porphyromonadaceae	976|Bacteroidetes	E	Belongs to the DegT DnrJ EryC1 family	degT	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
k141_3061_2	436114.SYO3AOP1_1407	4.79e-158	454.0	COG1089@1|root,COG1089@2|Bacteria,2G4I3@200783|Aquificae	200783|Aquificae	M	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose	gmd	-	4.2.1.47	ko:K01711	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R00888	RC00402	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
k141_3061_3	879212.DespoDRAFT_02839	6.15e-86	265.0	COG1082@1|root,COG1082@2|Bacteria,1NUZZ@1224|Proteobacteria,42WFH@68525|delta/epsilon subdivisions,2WV2N@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
k141_5346_1	457570.Nther_0831	1.13e-42	145.0	2C91C@1|root,30CC5@2|Bacteria,1V1Z2@1239|Firmicutes,24HJH@186801|Clostridia	186801|Clostridia	S	Putative redox-active protein (C_GCAxxG_C_C)	-	-	-	-	-	-	-	-	-	-	-	-	C_GCAxxG_C_C
k141_5346_2	1410653.JHVC01000019_gene2182	9.58e-63	196.0	COG1406@1|root,COG1406@2|Bacteria,1VD18@1239|Firmicutes,24HMR@186801|Clostridia,36ING@31979|Clostridiaceae	186801|Clostridia	N	Chemotaxis protein CheX	cheX	-	-	ko:K03409	ko02030,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheX
k141_5346_3	1230342.CTM_19949	4.24e-98	296.0	COG2197@1|root,COG2197@2|Bacteria,1UHXC@1239|Firmicutes,24BCY@186801|Clostridia,36F4X@31979|Clostridiaceae	186801|Clostridia	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	CheX,Response_reg
k141_5346_4	1121324.CLIT_14c00130	1.26e-99	294.0	COG1584@1|root,COG1584@2|Bacteria,1TSYX@1239|Firmicutes,249E0@186801|Clostridia,25QW0@186804|Peptostreptococcaceae	186801|Clostridia	S	GPR1/FUN34/yaaH family	yaaH	-	-	ko:K07034	-	-	-	-	ko00000	-	-	-	Grp1_Fun34_YaaH
k141_5346_5	1121324.CLIT_2c03390	1.49e-284	807.0	COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,2486F@186801|Clostridia,25SH8@186804|Peptostreptococcaceae	186801|Clostridia	O	C-terminal, D2-small domain, of ClpB protein	-	-	-	ko:K03697	-	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small
k141_5346_6	243277.VC_A0621	2.15e-26	106.0	COG2390@1|root,COG2390@2|Bacteria,1MX3F@1224|Proteobacteria,1RMEZ@1236|Gammaproteobacteria,1XT80@135623|Vibrionales	135623|Vibrionales	K	Transcriptional regulator, contains sigma factor-related N-terminal domain	lsrR	-	-	-	-	-	-	-	-	-	-	-	HTH_28,Sugar-bind
k141_5346_7	1121289.JHVL01000040_gene3173	4.62e-144	427.0	COG0534@1|root,COG0534@2|Bacteria,1TPFM@1239|Firmicutes,247J9@186801|Clostridia,36DJD@31979|Clostridiaceae	186801|Clostridia	V	MATE efflux family protein	mepA2	-	-	-	-	-	-	-	-	-	-	-	MatE
k141_5346_8	1408422.JHYF01000004_gene1679	1.52e-220	611.0	COG0115@1|root,COG0115@2|Bacteria,1TQQI@1239|Firmicutes,2480D@186801|Clostridia,36E7V@31979|Clostridiaceae	186801|Clostridia	E	Branched-chain amino acid aminotransferase	ilvE	-	2.6.1.42,4.1.3.38	ko:K00826,ko:K02619	ko00270,ko00280,ko00290,ko00770,ko00790,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map00790,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R05553,R10991	RC00006,RC00036,RC01843,RC02148	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
k141_5346_9	445971.ANASTE_01709	9.29e-40	137.0	COG1661@1|root,COG1661@2|Bacteria,1VBWE@1239|Firmicutes,24HQ2@186801|Clostridia,25XHZ@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	ko:K06934	-	-	-	-	ko00000	-	-	-	DUF296
k141_5346_10	1230342.CTM_15048	1.4e-88	298.0	COG0840@1|root,COG0840@2|Bacteria,1TP5A@1239|Firmicutes,247S3@186801|Clostridia,36EQK@31979|Clostridiaceae	186801|Clostridia	NT	chemotaxis	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal,PilJ,dCache_1,sCache_3_3
k141_5346_12	864565.HMPREF0379_0015	6.72e-50	165.0	COG0558@1|root,COG0558@2|Bacteria,1V6PJ@1239|Firmicutes,24J7Y@186801|Clostridia,25RAN@186804|Peptostreptococcaceae	186801|Clostridia	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pgsA	-	2.7.8.41,2.7.8.5	ko:K00995,ko:K08744	ko00564,ko01100,map00564,map01100	-	R01801,R02030	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
k141_5346_13	1151292.QEW_1706	5.85e-183	524.0	COG0621@1|root,COG0621@2|Bacteria,1TP2W@1239|Firmicutes,2487D@186801|Clostridia,25QPV@186804|Peptostreptococcaceae	186801|Clostridia	J	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12	rimO	-	2.8.4.4	ko:K14441	-	-	R10652	RC00003,RC03217	ko00000,ko01000,ko03009	-	-	-	Radical_SAM,TRAM,UPF0004
k141_5346_14	1408823.AXUS01000004_gene241	3.8e-103	314.0	COG2603@1|root,COG2603@2|Bacteria,1TQ8T@1239|Firmicutes,24AM7@186801|Clostridia,25T6W@186804|Peptostreptococcaceae	186801|Clostridia	S	Rhodanese Homology Domain	selU	-	-	ko:K06917	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Rhodanese
k141_5346_15	1476973.JMMB01000007_gene1086	5.06e-129	384.0	COG0527@1|root,COG0527@2|Bacteria,1TPQJ@1239|Firmicutes,24811@186801|Clostridia,25QHR@186804|Peptostreptococcaceae	186801|Clostridia	E	ACT domain	dapG	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT_7
k141_5346_16	1391646.AVSU01000058_gene1019	0.0	944.0	COG1185@1|root,COG1185@2|Bacteria,1TQDW@1239|Firmicutes,248RW@186801|Clostridia,25QG3@186804|Peptostreptococcaceae	186801|Clostridia	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	-	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
k141_5346_17	1286171.EAL2_c13160	3.43e-39	132.0	COG0184@1|root,COG0184@2|Bacteria,1VA5C@1239|Firmicutes,24MRM@186801|Clostridia,25WWJ@186806|Eubacteriaceae	186801|Clostridia	J	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome	rpsO	-	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
k141_5346_18	1121324.CLIT_11c02400	1.85e-105	317.0	COG0196@1|root,COG0196@2|Bacteria,1TPKS@1239|Firmicutes,2484A@186801|Clostridia,25QRH@186804|Peptostreptococcaceae	186801|Clostridia	H	Belongs to the ribF family	ribF	-	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
k141_5346_19	1121324.CLIT_11c02390	1.12e-96	294.0	COG0130@1|root,COG0130@2|Bacteria,1TP9Y@1239|Firmicutes,24B46@186801|Clostridia,25QIQ@186804|Peptostreptococcaceae	186801|Clostridia	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	-	5.4.99.25	ko:K03177	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruB-C_2,TruB_C_2,TruB_N
k141_5346_20	1391646.AVSU01000058_gene1024	3.02e-99	302.0	COG0618@1|root,COG0618@2|Bacteria,1TPXX@1239|Firmicutes,248R3@186801|Clostridia,25R43@186804|Peptostreptococcaceae	186801|Clostridia	S	DHHA1 domain protein	nrnA	-	3.1.13.3,3.1.3.7	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
k141_5346_21	1391646.AVSU01000058_gene1025	1.08e-40	138.0	COG0858@1|root,COG0858@2|Bacteria,1VA0P@1239|Firmicutes,24MPB@186801|Clostridia,25RK5@186804|Peptostreptococcaceae	186801|Clostridia	J	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA	rbfA	-	-	ko:K02834	-	-	-	-	ko00000,ko03009	-	-	-	RBFA
k141_5346_22	1286171.EAL2_c13210	0.0	906.0	COG0532@1|root,COG0532@2|Bacteria,1TPAI@1239|Firmicutes,248SJ@186801|Clostridia,25V39@186806|Eubacteriaceae	186801|Clostridia	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,IF-2,IF2_N
k141_5346_23	596315.HMPREF0634_1221	4.38e-25	97.8	COG1358@1|root,COG1358@2|Bacteria,1VEYG@1239|Firmicutes,24QP3@186801|Clostridia,25RPK@186804|Peptostreptococcaceae	186801|Clostridia	J	Ribosomal protein L7Ae/L30e/S12e/Gadd45 family	-	-	-	-	-	-	-	-	-	-	-	-	Ribosomal_L7Ae
k141_5346_24	1121324.CLIT_11c02340	5.38e-34	119.0	COG2740@1|root,COG2740@2|Bacteria,1VEJS@1239|Firmicutes,24QSJ@186801|Clostridia	186801|Clostridia	K	Nucleic-acid-binding protein implicated in transcription termination	ylxR	-	-	ko:K07742	-	-	-	-	ko00000	-	-	-	DUF448
k141_5346_25	1121324.CLIT_11c02330	3.42e-177	503.0	COG0195@1|root,COG0195@2|Bacteria,1TPB3@1239|Firmicutes,247W8@186801|Clostridia,25QTZ@186804|Peptostreptococcaceae	186801|Clostridia	K	Participates in both transcription termination and antitermination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KH_5,NusA_N,S1
k141_5346_26	1348908.KI518587_gene2989	2.75e-33	122.0	COG0779@1|root,COG0779@2|Bacteria,1V6KT@1239|Firmicutes,4HH88@91061|Bacilli,1ZG6S@1386|Bacillus	91061|Bacilli	S	Required for maturation of 30S ribosomal subunits	rimP	GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576	-	ko:K09748	-	-	-	-	ko00000,ko03009	-	-	-	DUF150,DUF150_C
k141_5346_27	1391646.AVSU01000066_gene720	0.0	1661.0	COG2176@1|root,COG2176@2|Bacteria,1TPAG@1239|Firmicutes,248YB@186801|Clostridia,25QR9@186804|Peptostreptococcaceae	186801|Clostridia	L	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity	polC	-	2.7.7.7	ko:K02342,ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_a_NI,DNA_pol3_a_NII,DNA_pol3_alpha,HHH_6,PHP,RNase_T,tRNA_anti-codon
k141_5346_28	1408823.AXUS01000027_gene1476	1.82e-153	443.0	COG0821@1|root,COG0821@2|Bacteria,1TPFR@1239|Firmicutes,247N1@186801|Clostridia,25QSI@186804|Peptostreptococcaceae	186801|Clostridia	I	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate	ispG	-	1.17.7.1,1.17.7.3	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R08689,R10859	RC01486	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS06430	GcpE
k141_5346_29	1031288.AXAA01000001_gene2296	5.61e-79	251.0	COG0750@1|root,COG0750@2|Bacteria,1TPMC@1239|Firmicutes,247MT@186801|Clostridia,36G12@31979|Clostridiaceae	186801|Clostridia	M	zinc metalloprotease	rseP	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_M50
k141_1171_4	1278307.KB907006_gene243	1.11e-116	346.0	COG5433@1|root,COG5433@2|Bacteria,1N9ZA@1224|Proteobacteria,1SJ16@1236|Gammaproteobacteria,2QJ3X@267894|Psychromonadaceae	1236|Gammaproteobacteria	L	transposase activity	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_assoc
k141_5173_1	1158292.JPOE01000002_gene2932	0.000249	44.3	COG0479@1|root,COG0479@2|Bacteria,1QVWG@1224|Proteobacteria	1224|Proteobacteria	C	4Fe-4S dicluster domain	asrA	-	-	ko:K16950	ko00920,ko01120,map00920,map01120	-	R00858,R10146	RC00065	ko00000,ko00001	-	-	-	Fer4_22
k141_5173_2	472759.Nhal_1355	5.33e-36	125.0	COG0375@1|root,COG0375@2|Bacteria,1MZJH@1224|Proteobacteria,1S5WG@1236|Gammaproteobacteria,1WYQN@135613|Chromatiales	135613|Chromatiales	S	Probably plays a role in a hydrogenase nickel cofactor insertion step	hypA	-	-	ko:K04651	-	-	-	-	ko00000,ko03110	-	-	-	HypA
k141_5173_3	1141663.OOC_06037	1.48e-92	286.0	COG0378@1|root,COG0378@2|Bacteria,1MVBD@1224|Proteobacteria,1RN9Y@1236|Gammaproteobacteria,3Z8NE@586|Providencia	1236|Gammaproteobacteria	KO	UreA amidohydrolase (urease) regulatory and maturation protein UreG	hypB	-	-	ko:K04652	-	-	-	-	ko00000,ko03110	-	-	-	cobW
k141_5173_4	221988.MS2358	3.04e-23	91.7	COG0298@1|root,COG0298@2|Bacteria,1RGXH@1224|Proteobacteria,1S96I@1236|Gammaproteobacteria,1Y90M@135625|Pasteurellales	135625|Pasteurellales	O	Hydrogenase 2 accessory protein	hypC	-	-	ko:K04653	-	-	-	-	ko00000	-	-	-	HupF_HypC
k141_5173_5	598467.BrE312_1385	2.96e-182	516.0	COG0409@1|root,COG0409@2|Bacteria,1MU1F@1224|Proteobacteria,1RRTQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	Belongs to the HypD family	hypD	GO:0003674,GO:0005488,GO:0005506,GO:0006464,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0019538,GO:0036211,GO:0042165,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0046872,GO:0046914,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0051604,GO:0070025,GO:0071704,GO:1901564	-	ko:K04654	-	-	-	-	ko00000	-	-	-	HypD
k141_5173_6	228399.appser1_14530	3.54e-157	450.0	COG0309@1|root,COG0309@2|Bacteria,1MVCC@1224|Proteobacteria,1RQBE@1236|Gammaproteobacteria,1Y78N@135625|Pasteurellales	135625|Pasteurellales	O	hydrogenase expression formation protein HypE	hypE	-	-	ko:K04655	-	-	-	-	ko00000	-	-	-	AIRS,AIRS_C
k141_5173_7	1111728.ATYS01000075_gene3516	1.87e-55	196.0	COG0068@1|root,COG0068@2|Bacteria,1MVP8@1224|Proteobacteria,1RP08@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide	hypF	GO:0003674,GO:0003824,GO:0005488,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009987,GO:0010467,GO:0016740,GO:0016741,GO:0016743,GO:0019538,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0046872,GO:0046914,GO:0046944,GO:0051604,GO:0071704,GO:1901564	-	ko:K04656	-	-	-	-	ko00000	-	-	-	Acylphosphatase,Sua5_yciO_yrdC,zf-HYPF
k141_2443_1	469617.FUAG_01161	3.42e-22	95.1	COG2031@1|root,COG2031@2|Bacteria,37969@32066|Fusobacteria	32066|Fusobacteria	I	Short chain fatty acid transporter	-	-	-	-	-	-	-	-	-	-	-	-	SCFA_trans
k141_2443_2	768706.Desor_2354	2.27e-126	370.0	COG1250@1|root,COG1250@2|Bacteria,1TPJS@1239|Firmicutes,248AE@186801|Clostridia,261TN@186807|Peptococcaceae	186801|Clostridia	I	PFAM 3-hydroxyacyl-CoA dehydrogenase	-	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
k141_2443_3	469617.FUAG_01159	3.61e-114	334.0	COG3246@1|root,COG3246@2|Bacteria,378JF@32066|Fusobacteria	32066|Fusobacteria	S	beta-keto acid cleavage enzyme	-	-	-	-	-	-	-	-	-	-	-	-	BKACE
k141_190_1	1121441.AUCX01000014_gene513	3.21e-100	319.0	COG3170@1|root,COG3170@2|Bacteria,1N4R0@1224|Proteobacteria,42QKG@68525|delta/epsilon subdivisions,2WMF1@28221|Deltaproteobacteria,2MBE5@213115|Desulfovibrionales	28221|Deltaproteobacteria	NU	Tfp pilus assembly protein FimV	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_190_2	1498011.A0A096XUU0_9CAUD	6.25e-116	357.0	4QG38@10239|Viruses,4QQVI@28883|Caudovirales,4QNWM@10744|Podoviridae	10744|Podoviridae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_1172_1	1278307.KB907003_gene371	0.0	1164.0	COG1012@1|root,COG1454@1|root,COG1012@2|Bacteria,COG1454@2|Bacteria,1MVPH@1224|Proteobacteria,1RNBH@1236|Gammaproteobacteria,2QHWH@267894|Psychromonadaceae	1236|Gammaproteobacteria	C	belongs to the iron- containing alcohol dehydrogenase family	adhE	GO:0003674,GO:0003824,GO:0004022,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006067,GO:0006115,GO:0008150,GO:0008152,GO:0008774,GO:0009058,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0016620,GO:0016903,GO:0016999,GO:0017000,GO:0017144,GO:0034308,GO:0034309,GO:0042802,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0055114,GO:0071704,GO:1901576,GO:1901615,GO:1901617	1.1.1.1,1.2.1.10	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	-	R00228,R00623,R00754,R01172,R04880,R05233,R05234,R06917,R06927	RC00004,RC00050,RC00088,RC00099,RC00116,RC00184,RC00649,RC01195	ko00000,ko00001,ko01000	-	-	iEcE24377_1341.EcE24377A_1389,iYL1228.KPN_02199	Aldedh,Fe-ADH
k141_191_1	1121396.KB893057_gene2538	3.14e-105	314.0	COG4992@1|root,COG4992@2|Bacteria,1MV3C@1224|Proteobacteria,42MHH@68525|delta/epsilon subdivisions,2WIMW@28221|Deltaproteobacteria,2MHRT@213118|Desulfobacterales	28221|Deltaproteobacteria	E	TIGRFAM acetylornithine and succinylornithine	argD	-	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	iAF987.Gmet_0204	Aminotran_3
k141_3527_1	29495.EA26_10045	4.11e-63	202.0	COG0516@1|root,COG0516@2|Bacteria,1MUJM@1224|Proteobacteria,1RPZY@1236|Gammaproteobacteria,1XUGZ@135623|Vibrionales	135623|Vibrionales	F	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides	guaC	GO:0003674,GO:0003824,GO:0003920,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0015949,GO:0016491,GO:0016651,GO:0016657,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:1901360	1.7.1.7	ko:K00364	ko00230,map00230	-	R01134	RC00457	ko00000,ko00001,ko01000	-	-	-	IMPDH
k141_3527_4	1348635.BBJY01000003_gene3788	8.34e-194	555.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,1MU1Q@1224|Proteobacteria,1RMPS@1236|Gammaproteobacteria,1XTWB@135623|Vibrionales	135623|Vibrionales	H	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	Carb_kinase,YjeF_N
k141_3527_7	945550.VISI1226_09609	2.19e-19	80.5	COG3036@1|root,COG3036@2|Bacteria,1NH0E@1224|Proteobacteria,1SGZX@1236|Gammaproteobacteria,1XZ24@135623|Vibrionales	135623|Vibrionales	S	Domain of unknown function	-	-	-	ko:K09890	-	-	-	-	ko00000,ko03012	-	-	-	DUF331
k141_3527_9	1219065.VPR01S_13_00780	1.78e-219	614.0	COG2195@1|root,COG2195@2|Bacteria,1MV7D@1224|Proteobacteria,1RMKZ@1236|Gammaproteobacteria,1XTBU@135623|Vibrionales	135623|Vibrionales	E	Cleaves the N-terminal amino acid of tripeptides	pepT	GO:0003674,GO:0003824,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:0140096,GO:1901564	3.4.11.4	ko:K01258	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M42
k141_3527_11	243277.VC_A0177	1.59e-14	68.2	2AWN1@1|root,31NIT@2|Bacteria,1QK9F@1224|Proteobacteria,1TICX@1236|Gammaproteobacteria,1XYW9@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_3527_12	1348635.BBJY01000003_gene3832	7.15e-194	541.0	COG0714@1|root,COG0714@2|Bacteria,1MUFN@1224|Proteobacteria,1RN5G@1236|Gammaproteobacteria,1XURM@135623|Vibrionales	135623|Vibrionales	S	COG0714 MoxR-like ATPases	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
k141_3527_13	1348635.BBJY01000003_gene3833	1.09e-129	378.0	COG1721@1|root,COG1721@2|Bacteria,1Q7RR@1224|Proteobacteria,1RNNP@1236|Gammaproteobacteria,1XSBV@135623|Vibrionales	135623|Vibrionales	S	conserved protein (some members contain a von Willebrand factor type A (vWA) domain)	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
k141_3527_14	945550.VISI1226_03750	9.88e-56	179.0	2C5QF@1|root,331W9@2|Bacteria,1N7AE@1224|Proteobacteria,1SCH2@1236|Gammaproteobacteria,1XXHT@135623|Vibrionales	135623|Vibrionales	S	Domain of unknown function (DUF4381)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4381
k141_3527_16	55601.VANGNB10_cII0790	4.65e-159	478.0	COG0457@1|root,COG2304@1|root,COG0457@2|Bacteria,COG2304@2|Bacteria,1MW51@1224|Proteobacteria,1RMD3@1236|Gammaproteobacteria,1XVCX@135623|Vibrionales	135623|Vibrionales	S	protein containing a von Willebrand factor type A (vWA) domain	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	TPR_1,TPR_19,TPR_2,VWA_2
k141_3527_17	314292.VAS14_09564	7.6e-75	255.0	COG0457@1|root,COG0457@2|Bacteria,1MXK4@1224|Proteobacteria,1RNFM@1236|Gammaproteobacteria,1XU0S@135623|Vibrionales	135623|Vibrionales	S	Oxygen tolerance	-	-	-	-	-	-	-	-	-	-	-	-	BatD
k141_3527_18	345073.VC395_A0157	1.05e-65	205.0	COG3034@1|root,COG3034@2|Bacteria,1MXY6@1224|Proteobacteria,1S66I@1236|Gammaproteobacteria,1XXH1@135623|Vibrionales	135623|Vibrionales	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
k141_3527_19	1190603.AJYD01000016_gene1929	2.08e-33	117.0	COG3530@1|root,COG3530@2|Bacteria,1N7GT@1224|Proteobacteria,1SCBX@1236|Gammaproteobacteria,1XYDT@135623|Vibrionales	135623|Vibrionales	S	protein conserved in bacteria	STM2426	-	-	ko:K09954	-	-	-	-	ko00000	-	-	-	QSregVF_b
k141_3527_20	1051646.VITU9109_15998	2.45e-148	425.0	COG0524@1|root,COG0524@2|Bacteria,1MX38@1224|Proteobacteria,1RRWT@1236|Gammaproteobacteria,1XU45@135623|Vibrionales	135623|Vibrionales	G	belongs to the carbohydrate kinase PfkB family	scrK	-	2.7.1.4	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	-	R00760,R00867,R03920	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
k141_3527_21	945543.VIBR0546_16596	3.11e-212	607.0	COG1621@1|root,COG1621@2|Bacteria,1MWTX@1224|Proteobacteria,1RRZ2@1236|Gammaproteobacteria,1XUR7@135623|Vibrionales	135623|Vibrionales	G	COG1621 Beta-fructosidases (levanase invertase)	-	GO:0003674,GO:0003824,GO:0004553,GO:0004564,GO:0005975,GO:0005984,GO:0005985,GO:0005987,GO:0008150,GO:0008152,GO:0009056,GO:0009311,GO:0009313,GO:0009987,GO:0016052,GO:0016787,GO:0016798,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044275,GO:0046352,GO:0071704,GO:1901575	3.2.1.26	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00801,R00802,R02410,R03635,R03921,R06088	RC00028,RC00077	ko00000,ko00001,ko01000	-	GH32	-	Glyco_hydro_32C,Glyco_hydro_32N
k141_3527_22	1348635.BBJY01000004_gene2926	5.22e-178	502.0	COG1609@1|root,COG1609@2|Bacteria,1RKJ6@1224|Proteobacteria,1SMZS@1236|Gammaproteobacteria,1XSDZ@135623|Vibrionales	135623|Vibrionales	K	Sucrose operon repressor	-	-	-	ko:K03484	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
k141_3527_23	55601.VANGNB10_cI1444	1.2e-273	757.0	COG1263@1|root,COG1264@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,1MVVJ@1224|Proteobacteria,1RRDA@1236|Gammaproteobacteria,1XU13@135623|Vibrionales	135623|Vibrionales	G	COG1264 Phosphotransferase system IIB components	scrA	-	2.7.1.211	ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	M00269	R00811	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.1.2.1,4.A.1.2.10,4.A.1.2.12,4.A.1.2.9	-	-	PTS_EIIB,PTS_EIIC
k141_3527_24	1348635.BBJY01000001_gene2669	1.26e-232	665.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,1XU0F@135623|Vibrionales	135623|Vibrionales	NT	Cache domain	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal,dCache_1
k141_3527_25	1219065.VPR01S_13_00380	8.28e-98	292.0	COG3338@1|root,COG3338@2|Bacteria,1PEA6@1224|Proteobacteria,1RSM9@1236|Gammaproteobacteria,1XT7N@135623|Vibrionales	135623|Vibrionales	P	carbonic anhydrase	cah	-	4.2.1.1	ko:K01674	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Carb_anhydrase
k141_3527_26	55601.VANGNB10_cII0284c	1.88e-39	134.0	2B22N@1|root,31UJJ@2|Bacteria,1QSF4@1224|Proteobacteria,1THZ8@1236|Gammaproteobacteria,1XXZ8@135623|Vibrionales	135623|Vibrionales	S	transcriptional regulators	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_3527_27	55601.VANGNB10_cII0763c	8.43e-145	416.0	COG0457@1|root,COG0457@2|Bacteria,1PNM7@1224|Proteobacteria,1RXYT@1236|Gammaproteobacteria,1XVBC@135623|Vibrionales	135623|Vibrionales	S	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	Alkyl_sulf_dimr,TPR_8
k141_3527_28	55601.VANGNB10_cII0764	1.39e-225	628.0	COG0517@1|root,COG4175@1|root,COG0517@2|Bacteria,COG4175@2|Bacteria,1MU86@1224|Proteobacteria,1RN2R@1236|Gammaproteobacteria,1XTVT@135623|Vibrionales	135623|Vibrionales	E	COG4175 ABC-type proline glycine betaine transport system, ATPase component	proV	-	3.6.3.32	ko:K02000	ko02010,map02010	M00208	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.12	-	-	ABC_tran,CBS
k141_3527_29	357804.Ping_0615	2.1e-182	515.0	COG4176@1|root,COG4176@2|Bacteria,1MUM4@1224|Proteobacteria,1RPQS@1236|Gammaproteobacteria,2QJ2G@267894|Psychromonadaceae	1236|Gammaproteobacteria	P	Binding-protein-dependent transport system inner membrane component	proW	GO:0003674,GO:0005215,GO:0005275,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006836,GO:0006950,GO:0006970,GO:0006972,GO:0008150,GO:0009628,GO:0015695,GO:0015696,GO:0015697,GO:0015837,GO:0015838,GO:0015871,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0031460,GO:0032991,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0072337,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990351	-	ko:K02001,ko:K02002	ko02010,map02010	M00208	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	iEcSMS35_1347.EcSMS35_2800	BPD_transp_1
k141_3527_30	55601.VANGNB10_cII0766	2.64e-186	524.0	COG2113@1|root,COG2113@2|Bacteria,1MWZU@1224|Proteobacteria,1RNDF@1236|Gammaproteobacteria,1XUND@135623|Vibrionales	135623|Vibrionales	E	Substrate binding domain of ABC-type glycine betaine transport system	proX	-	-	ko:K02002	ko02010,map02010	M00208	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	OpuAC
k141_3527_31	55601.VANGNB10_cII0767	2.16e-52	171.0	COG1846@1|root,COG1846@2|Bacteria,1RF8X@1224|Proteobacteria,1S4RW@1236|Gammaproteobacteria,1XX10@135623|Vibrionales	135623|Vibrionales	K	COG1846 Transcriptional regulators	-	-	-	-	-	-	-	-	-	-	-	-	MarR
k141_3527_33	1238450.VIBNISOn1_1420005	0.0	898.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1XSRH@135623|Vibrionales	135623|Vibrionales	T	signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
k141_3527_34	1238450.VIBNISOn1_1420006	5.31e-145	422.0	COG1879@1|root,COG1879@2|Bacteria,1MUJU@1224|Proteobacteria,1RQ8E@1236|Gammaproteobacteria,1XT09@135623|Vibrionales	135623|Vibrionales	G	Periplasmic binding protein domain	-	-	-	ko:K10439	ko02010,ko02030,map02010,map02030	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	Peripla_BP_4
k141_3527_35	1238450.VIBNISOn1_1420007	7.94e-167	477.0	COG1879@1|root,COG1879@2|Bacteria,1NKCW@1224|Proteobacteria,1RT5N@1236|Gammaproteobacteria,1XV03@135623|Vibrionales	135623|Vibrionales	G	COG1879 ABC-type sugar transport system, periplasmic component	-	-	-	ko:K10910	ko02020,ko02024,ko05111,map02020,map02024,map05111	-	-	-	ko00000,ko00001	-	-	-	Peripla_BP_4
k141_3527_36	675814.VIC_002777	1.6e-170	503.0	COG0365@1|root,COG0365@2|Bacteria,1MUX7@1224|Proteobacteria,1RPGT@1236|Gammaproteobacteria,1XVRA@135623|Vibrionales	135623|Vibrionales	I	COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases	acs-2	-	6.2.1.16	ko:K01907	ko00280,ko00650,map00280,map00650	-	R01357	RC00004,RC00014	ko00000,ko00001,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
k141_3527_37	345073.VC395_A1125	2.27e-144	428.0	COG0642@1|root,COG2205@2|Bacteria,1N1Z2@1224|Proteobacteria,1RPG9@1236|Gammaproteobacteria,1XV7G@135623|Vibrionales	135623|Vibrionales	T	His Kinase A (phosphoacceptor) domain	-	-	2.7.13.3	ko:K07645	ko02020,ko02024,map02020,map02024	M00453	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	2CSK_N,HATPase_c,HisKA
k141_3527_38	1348635.BBJY01000001_gene2623	3.12e-113	329.0	COG0745@1|root,COG0745@2|Bacteria,1N0YI@1224|Proteobacteria,1RPNH@1236|Gammaproteobacteria,1Y2IA@135623|Vibrionales	135623|Vibrionales	K	Transcriptional regulatory protein, C terminal	-	-	-	ko:K07666	ko02020,ko02024,map02020,map02024	M00453	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
k141_3527_39	1348635.BBJY01000001_gene2622	5.88e-94	280.0	COG3063@1|root,COG3063@2|Bacteria,1RD9T@1224|Proteobacteria,1S3R3@1236|Gammaproteobacteria,1XX1A@135623|Vibrionales	135623|Vibrionales	NU	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_19,TPR_8
k141_3527_40	675815.VOA_001131	9.96e-86	263.0	COG0300@1|root,COG0300@2|Bacteria,1RAFB@1224|Proteobacteria,1S2HE@1236|Gammaproteobacteria,1XVH5@135623|Vibrionales	135623|Vibrionales	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
k141_3527_41	1201293.AKXQ01000014_gene4108	1.06e-97	306.0	COG1022@1|root,COG1022@2|Bacteria,1MU4D@1224|Proteobacteria,1RPNE@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	COG1022 Long-chain acyl-CoA synthetases (AMP-forming)	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,Haem_oxygenas_2
k141_3527_42	675815.VOA_001133	1.15e-143	428.0	COG1022@1|root,COG1022@2|Bacteria,1MU4D@1224|Proteobacteria,1RPNE@1236|Gammaproteobacteria,1XSHH@135623|Vibrionales	135623|Vibrionales	I	AMP-binding enzyme	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding
k141_3539_33	675814.VIC_002298	1.72e-30	114.0	2DCKR@1|root,2ZEIY@2|Bacteria,1P706@1224|Proteobacteria,1SUSA@1236|Gammaproteobacteria,1XZIN@135623|Vibrionales	135623|Vibrionales	S	Killing trait	-	-	-	-	-	-	-	-	-	-	-	-	RebB
k141_3539_34	675814.VIC_002297	4.07e-44	145.0	2CU57@1|root,333RB@2|Bacteria,1N95P@1224|Proteobacteria,1SZR2@1236|Gammaproteobacteria,1XZ0K@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_3539_35	717774.Marme_2674	1.07e-46	150.0	2BI4W@1|root,32UP6@2|Bacteria,1N6BF@1224|Proteobacteria,1SQZ3@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Killing trait	-	-	-	-	-	-	-	-	-	-	-	-	RebB
k141_3539_37	675814.VIC_002294	9.43e-37	125.0	2A7VA@1|root,30WUK@2|Bacteria,1PIJ2@1224|Proteobacteria,1RVAT@1236|Gammaproteobacteria,1Y1H5@135623|Vibrionales	135623|Vibrionales	S	Killing trait	-	-	-	-	-	-	-	-	-	-	-	-	RebB
k141_3539_38	675814.VIC_002293	9.8e-27	99.0	2AXKA@1|root,31PKH@2|Bacteria,1QMA1@1224|Proteobacteria,1TJI8@1236|Gammaproteobacteria,1Y19V@135623|Vibrionales	135623|Vibrionales	S	Killing trait	-	-	-	-	-	-	-	-	-	-	-	-	RebB
k141_3539_39	675814.VIC_002292	8.69e-128	380.0	COG2204@1|root,COG2207@1|root,COG2204@2|Bacteria,COG2207@2|Bacteria,1N1CY@1224|Proteobacteria,1SBMK@1236|Gammaproteobacteria,1Y2SY@135623|Vibrionales	135623|Vibrionales	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18,HTH_AraC,Response_reg,Sigma54_activ_2
k141_3539_40	1348635.BBJY01000010_gene1327	5.68e-71	218.0	COG3090@1|root,COG3090@2|Bacteria,1RJ8K@1224|Proteobacteria,1SA02@1236|Gammaproteobacteria,1XUQB@135623|Vibrionales	135623|Vibrionales	G	TRAP-type C4-dicarboxylate transport system, small permease component	-	-	-	-	-	-	-	-	-	-	-	-	DctQ
k141_3539_41	1348635.BBJY01000010_gene1328	1.61e-253	704.0	COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,1RNAM@1236|Gammaproteobacteria,1XTIW@135623|Vibrionales	135623|Vibrionales	G	TRAP-type C4-dicarboxylate transport system, large permease component	-	-	-	-	-	-	-	-	-	-	-	-	DctM
k141_3539_42	1348635.BBJY01000010_gene1329	3.11e-162	461.0	COG1638@1|root,COG1638@2|Bacteria,1MVHC@1224|Proteobacteria,1RPNJ@1236|Gammaproteobacteria,1XU8W@135623|Vibrionales	135623|Vibrionales	G	TRAP-type C4-dicarboxylate transport system, periplasmic component	-	-	-	ko:K11688	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.56.1	-	-	DctP
k141_3539_45	1005395.CSV86_05467	7.13e-10	65.5	COG0834@1|root,COG0834@2|Bacteria,1RH2S@1224|Proteobacteria,1S9QV@1236|Gammaproteobacteria,1YWR8@136845|Pseudomonas putida group	1236|Gammaproteobacteria	ET	Bacterial extracellular solute-binding proteins, family 3	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
k141_3539_47	1203606.HMPREF1526_01169	1.35e-204	580.0	COG2211@1|root,COG2211@2|Bacteria,1TRA5@1239|Firmicutes,24ABB@186801|Clostridia,36EHN@31979|Clostridiaceae	186801|Clostridia	G	MFS/sugar transport protein	-	-	-	ko:K03292	-	-	-	-	ko00000	2.A.2	-	-	MFS_2
k141_2818_1	697303.Thewi_1464	1.22e-51	172.0	COG0194@1|root,COG0194@2|Bacteria,1TP0M@1239|Firmicutes,24HEX@186801|Clostridia,42ENR@68295|Thermoanaerobacterales	186801|Clostridia	F	Essential for recycling GMP and indirectly, cGMP	gmk	-	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_kin
k141_2818_2	1304885.AUEY01000008_gene2049	8.79e-30	108.0	COG2052@1|root,COG2052@2|Bacteria,1N0KP@1224|Proteobacteria,42TSK@68525|delta/epsilon subdivisions,2WQHH@28221|Deltaproteobacteria,2MKN3@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Belongs to the UPF0296 family	-	-	-	ko:K09777	-	-	-	-	ko00000	-	-	-	DUF370
k141_4585_4	500633.CLOHIR_02119	1.83e-69	217.0	COG0425@1|root,COG0425@2|Bacteria,1V6BY@1239|Firmicutes,24JW8@186801|Clostridia,25RGG@186804|Peptostreptococcaceae	186801|Clostridia	O	Belongs to the sulfur carrier protein TusA family	yedF	-	-	ko:K04085	ko04122,map04122	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	DrsE,TusA
k141_4585_11	478749.BRYFOR_09714	1.23e-08	53.1	2DQM3@1|root,337J4@2|Bacteria,1VGN5@1239|Firmicutes,24QUF@186801|Clostridia	186801|Clostridia	S	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_16
k141_4585_16	1123009.AUID01000012_gene1640	4.58e-13	65.5	2DR4V@1|root,33A63@2|Bacteria,1VKGM@1239|Firmicutes,25NVB@186801|Clostridia,26C13@186813|unclassified Clostridiales	186801|Clostridia	S	Protein of unknown function (DUF3343)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3343
k141_4585_17	1286171.EAL2_c22140	3.46e-27	100.0	COG4481@1|root,COG4481@2|Bacteria,1VEQ7@1239|Firmicutes,24QKA@186801|Clostridia,25X9G@186806|Eubacteriaceae	186801|Clostridia	S	Bacterial protein of unknown function (DUF951)	-	-	-	-	-	-	-	-	-	-	-	-	DUF951
k141_4585_23	345219.Bcoa_1827	3.15e-37	152.0	COG4842@1|root,COG5444@1|root,COG4842@2|Bacteria,COG5444@2|Bacteria,1UJJY@1239|Firmicutes,4IQ2G@91061|Bacilli,1ZRH3@1386|Bacillus	91061|Bacilli	S	LXG domain of WXG superfamily	-	-	-	ko:K21493	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	LXG
k141_4585_30	997346.HMPREF9374_2730	4.09e-40	141.0	2DNID@1|root,32XP3@2|Bacteria,1UJYK@1239|Firmicutes	1239|Firmicutes	S	Cysteine-rich CPCC	-	-	-	-	-	-	-	-	-	-	-	-	Cys_rich_CPCC
k141_4585_31	1408422.JHYF01000009_gene1992	1.62e-34	123.0	COG1669@1|root,COG1669@2|Bacteria,1VBHH@1239|Firmicutes,24JZE@186801|Clostridia,36JH2@31979|Clostridiaceae	186801|Clostridia	S	DNA polymerase beta domain protein region	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_2
k141_1598_1	56107.Cylst_4418	3.77e-185	577.0	COG0604@1|root,COG3321@1|root,COG0604@2|Bacteria,COG3321@2|Bacteria,1FZXE@1117|Cyanobacteria,1HIGN@1161|Nostocales	1117|Cyanobacteria	CQ	acyl transferase domain	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N_2,AMP-binding,AMP-binding_C,Acyl_transf_1,Condensation,KAsynt_C_assoc,KR,Ketoacyl-synt_C,Methyltransf_12,PP-binding,PS-DH,Thioesterase,ketoacyl-synt
k141_1598_2	43989.cce_3073	4.5e-149	479.0	COG1020@1|root,COG1020@2|Bacteria,1G0XE@1117|Cyanobacteria,3KJ4W@43988|Cyanothece	1117|Cyanobacteria	Q	TIGRFAM amino acid adenylation domain protein	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,Methyltransf_11,PP-binding,Thioesterase
k141_5041_1	1168034.FH5T_19640	5.83e-176	501.0	COG1457@1|root,COG1457@2|Bacteria,4NZ2M@976|Bacteroidetes	976|Bacteroidetes	F	Permease for cytosine/purines, uracil, thiamine, allantoin	-	-	-	ko:K10974	-	-	-	-	ko00000,ko02000	2.A.39.1	-	-	Transp_cyt_pur
k141_1334_2	1348635.BBJY01000010_gene1392	2.29e-61	192.0	COG0454@1|root,COG0456@2|Bacteria,1RA6D@1224|Proteobacteria,1S8VJ@1236|Gammaproteobacteria,1XX7T@135623|Vibrionales	135623|Vibrionales	K	FR47-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
k141_1334_4	1219065.VPR01S_03_00950	6.48e-242	670.0	COG0019@1|root,COG0019@2|Bacteria,1MZ7Y@1224|Proteobacteria,1RQJ4@1236|Gammaproteobacteria,1XVHW@135623|Vibrionales	135623|Vibrionales	E	Pyridoxal-dependent decarboxylase, pyridoxal binding domain	-	-	4.1.1.17	ko:K01581	ko00330,ko00480,ko01100,ko01110,ko01130,map00330,map00480,map01100,map01110,map01130	M00134	R00670	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
k141_1334_5	1116375.VEJY3_06780	6.86e-306	845.0	COG0654@1|root,COG0654@2|Bacteria,1MX9R@1224|Proteobacteria,1SYDP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	CH	Catalyzes the insertion of one atom of molecular oxygen into position 2 of the phenyl ring of 3-(3- hydroxyphenyl)propionate (3-HPP) and hydroxycinnamic acid (3HCI)	mhpA	GO:0006066,GO:0006082,GO:0006725,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016054,GO:0019439,GO:0019622,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046164,GO:0046395,GO:0046435,GO:0071704,GO:0072329,GO:1901360,GO:1901361,GO:1901575,GO:1901615,GO:1901616	1.14.13.127	ko:K05712	ko00360,ko01120,ko01220,map00360,map01120,map01220	M00545	R06786,R06787	RC00236	ko00000,ko00001,ko00002,ko01000	-	-	iECO103_1326.ECO103_0329	FAD_binding_3
k141_1334_6	1116375.VEJY3_06785	2.9e-170	483.0	COG3384@1|root,COG3384@2|Bacteria,1MW77@1224|Proteobacteria,1RR43@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Catalyzes the non-heme iron(II)-dependent oxidative cleavage of 2,3-dihydroxyphenylpropionic acid and 2,3- dihydroxicinnamic acid into 2-hydroxy-6-ketononadienedioate and 2- hydroxy-6-ketononatrienedioate, respectively	mhpB	GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0006066,GO:0006082,GO:0006725,GO:0008150,GO:0008152,GO:0008198,GO:0009056,GO:0009698,GO:0009987,GO:0016054,GO:0016491,GO:0016701,GO:0016702,GO:0019439,GO:0019622,GO:0019748,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046164,GO:0046271,GO:0046395,GO:0046435,GO:0046872,GO:0046914,GO:0047070,GO:0051213,GO:0055114,GO:0071704,GO:0072329,GO:1901360,GO:1901361,GO:1901575,GO:1901615,GO:1901616	1.13.11.16,1.13.11.57	ko:K04099,ko:K05713	ko00360,ko00627,ko01120,ko01220,map00360,map00627,map01120,map01220	M00545	R03550,R04280,R04376,R06788,R09565	RC00233,RC00535,RC01140,RC01364,RC02567,RC02694	br01602,ko00000,ko00001,ko00002,ko01000	-	-	iECIAI1_1343.ECIAI1_0349,iECO111_1330.ECO111_0384,iECO26_1355.ECO26_0384,iECSE_1348.ECSE_0373,iECW_1372.ECW_m0426,iEKO11_1354.EKO11_3494,iEcE24377_1341.EcE24377A_0372,iEcHS_1320.EcHS_A0412,iWFL_1372.ECW_m0426	LigB
k141_1334_7	1116375.VEJY3_06790	3.08e-184	514.0	COG2021@1|root,COG2021@2|Bacteria	2|Bacteria	E	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine	mhpC	-	3.7.1.14	ko:K05714	ko00360,ko01120,ko01220,map00360,map01120,map01220	M00545	R02603,R06789	RC00752,RC00753,RC01337	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_1
k141_1334_8	1116375.VEJY3_06795	2.03e-132	382.0	COG3971@1|root,COG3971@2|Bacteria,1RA35@1224|Proteobacteria,1S589@1236|Gammaproteobacteria,1XVYV@135623|Vibrionales	135623|Vibrionales	Q	2-keto-4-pentenoate hydratase	-	-	4.2.1.80	ko:K02554	ko00360,ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00360,map00362,map00621,map00622,map01100,map01120,map01220	M00545,M00569	R02601,R04781	RC00750,RC01213	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	-
k141_1334_9	911239.CF149_23836	2.24e-93	281.0	COG4569@1|root,COG4569@2|Bacteria,1MV23@1224|Proteobacteria,1RNDJ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD( ) and coenzyme A. Is the final enzyme in the meta- cleavage pathway for the degradation of aromatic compounds	mhpF	GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0008774,GO:0016491,GO:0016620,GO:0016903,GO:0055114	1.2.1.10	ko:K04073	ko00360,ko00362,ko00620,ko00621,ko00622,ko00650,ko01100,ko01120,ko01220,map00360,map00362,map00620,map00621,map00622,map00650,map01100,map01120,map01220	M00545,M00569	R00228,R01172	RC00004,RC00184,RC01195	br01602,ko00000,ko00001,ko00002,ko01000	-	-	iECO26_1355.ECO26_0387	AcetDehyd-dimer,Semialdhyde_dh
k141_1335_2	552811.Dehly_0472	3.27e-18	80.9	COG1433@1|root,COG1433@2|Bacteria	2|Bacteria	S	nitrogen fixation	VPA0323	-	-	-	-	-	-	-	-	-	-	-	Nitro_FeMo-Co
k141_5042_2	1121288.AULL01000013_gene1678	3.15e-40	137.0	COG4276@1|root,COG4276@2|Bacteria,4NQJG@976|Bacteroidetes,1I17G@117743|Flavobacteriia,3ZRSD@59732|Chryseobacterium	976|Bacteroidetes	S	SRPBCC domain-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc
k141_1599_1	86416.Clopa_4700	6.14e-26	112.0	COG5002@1|root,COG5002@2|Bacteria,1TPVJ@1239|Firmicutes,2489X@186801|Clostridia,36DS3@31979|Clostridiaceae	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
k141_1599_2	1298920.KI911353_gene2959	6.55e-60	196.0	COG0426@1|root,COG0426@2|Bacteria,1V80E@1239|Firmicutes,24EX9@186801|Clostridia,222KY@1506553|Lachnoclostridium	186801|Clostridia	C	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
k141_5043_1	1128398.Curi_c23850	1.44e-58	190.0	COG0462@1|root,COG0462@2|Bacteria,1TQ6Q@1239|Firmicutes,248ZN@186801|Clostridia,267T3@186813|unclassified Clostridiales	186801|Clostridia	EF	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	prs	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran_N
k141_5043_2	931626.Awo_c29990	1.29e-18	82.0	COG0193@1|root,COG0193@2|Bacteria,1V3NB@1239|Firmicutes,24HMC@186801|Clostridia,25W6U@186806|Eubacteriaceae	186801|Clostridia	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	-	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
k141_1600_1	177437.HRM2_06670	1.21e-121	366.0	COG0706@1|root,COG0706@2|Bacteria,1MV5M@1224|Proteobacteria,42MS8@68525|delta/epsilon subdivisions,2WJB6@28221|Deltaproteobacteria,2MJ96@213118|Desulfobacterales	28221|Deltaproteobacteria	U	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins	yidC	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP,YidC_periplas
k141_1336_1	177437.HRM2_08870	1.31e-35	131.0	COG1309@1|root,COG1309@2|Bacteria,1RK65@1224|Proteobacteria,42SGJ@68525|delta/epsilon subdivisions,2WPK2@28221|Deltaproteobacteria,2MK4T@213118|Desulfobacterales	28221|Deltaproteobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
k141_1336_2	879212.DespoDRAFT_03539	6.37e-26	109.0	COG1960@1|root,COG1960@2|Bacteria,1MU20@1224|Proteobacteria,42MUH@68525|delta/epsilon subdivisions,2WJ16@28221|Deltaproteobacteria,2MJ7S@213118|Desulfobacterales	28221|Deltaproteobacteria	I	acyl-CoA dehydrogenase	-	-	-	ko:K09456	-	-	-	-	ko00000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_C,Acyl-CoA_dh_M,Acyl-CoA_dh_N,AcylCoA_DH_N
k141_5044_1	177437.HRM2_00120	1.79e-189	569.0	COG0553@1|root,COG0553@2|Bacteria,1MV6M@1224|Proteobacteria,42M5P@68525|delta/epsilon subdivisions,2WIW8@28221|Deltaproteobacteria,2MIH9@213118|Desulfobacterales	28221|Deltaproteobacteria	L	SNF2 family N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,SNF2_N,SNF2_assoc
k141_3292_1	1348635.BBJY01000003_gene3939	1.65e-187	536.0	COG2211@1|root,COG2211@2|Bacteria,1MVUM@1224|Proteobacteria,1RP5J@1236|Gammaproteobacteria,1XT0V@135623|Vibrionales	135623|Vibrionales	G	COG2211 Na melibiose symporter and related transporters	-	-	-	ko:K03292	-	-	-	-	ko00000	2.A.2	-	-	MFS_2
k141_3292_2	324057.Pjdr2_0890	1.78e-203	585.0	COG3507@1|root,COG3507@2|Bacteria,1TP5K@1239|Firmicutes,4HA16@91061|Bacilli,26R05@186822|Paenibacillaceae	91061|Bacilli	G	Belongs to the glycosyl hydrolase 43 family	-	-	3.2.1.37	ko:K01198	ko00520,ko01100,map00520,map01100	-	R01433	RC00467	ko00000,ko00001,ko01000	-	GH43	-	Glyco_hydro_43
k141_3292_3	342610.Patl_3724	4.03e-101	308.0	COG1609@1|root,COG2207@1|root,COG1609@2|Bacteria,COG2207@2|Bacteria,1NYTD@1224|Proteobacteria,1RNGZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	transcriptional regulator	xylR	GO:0003674,GO:0003700,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2001141	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	HTH_18,HTH_AraC,Peripla_BP_3
k141_5290_1	55601.VANGNB10_cII0316	4.98e-86	257.0	COG0454@1|root,COG0456@2|Bacteria,1N4MF@1224|Proteobacteria,1S66R@1236|Gammaproteobacteria,1XWDA@135623|Vibrionales	135623|Vibrionales	K	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
k141_5290_2	675815.VOA_001715	1.57e-70	219.0	COG0637@1|root,COG0637@2|Bacteria,1PUMZ@1224|Proteobacteria,1RNJC@1236|Gammaproteobacteria,1XVSG@135623|Vibrionales	135623|Vibrionales	S	phosphatase phosphohexomutase	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
k141_5290_3	796620.VIBC2010_04859	4.41e-51	167.0	COG0545@1|root,COG0545@2|Bacteria,1RCWV@1224|Proteobacteria,1S7UP@1236|Gammaproteobacteria,1XWX0@135623|Vibrionales	135623|Vibrionales	O	COG0545 FKBP-type peptidyl-prolyl cis-trans isomerases 1	-	-	5.2.1.8	ko:K01802	-	-	-	-	ko00000,ko01000	-	-	-	FKBP_C,FKBP_N
k141_5290_4	1238450.VIBNISOn1_970082	5.46e-13	73.2	COG2885@1|root,COG2885@2|Bacteria,1MYBP@1224|Proteobacteria,1RVRF@1236|Gammaproteobacteria,1XW50@135623|Vibrionales	135623|Vibrionales	M	Belongs to the ompA family	yiaD	-	-	-	-	-	-	-	-	-	-	-	Gly-zipper_Omp,OmpA
k141_1339_1	1163617.SCD_n01286	4.64e-10	62.0	COG1721@1|root,COG1721@2|Bacteria,1R3QD@1224|Proteobacteria,2VN9P@28216|Betaproteobacteria	28216|Betaproteobacteria	S	conserved protein (some members contain a von Willebrand factor type A (vWA) domain)	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
k141_1339_2	1265505.ATUG01000001_gene3746	1.99e-23	107.0	COG1305@1|root,COG1305@2|Bacteria,1MWCE@1224|Proteobacteria,42NIZ@68525|delta/epsilon subdivisions,2WM5U@28221|Deltaproteobacteria,2MIWN@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Domain of unknown function (DUF3488)	-	-	2.3.2.13	ko:K22452	-	-	-	-	ko00000,ko01000	-	-	-	DUF3488,DUF4129,Transglut_core
k141_1341_1	243277.VC_A0568	4.41e-24	101.0	28IW1@1|root,2Z8UB@2|Bacteria,1N1QM@1224|Proteobacteria,1RR0J@1236|Gammaproteobacteria,1XSR0@135623|Vibrionales	135623|Vibrionales	S	F plasmid transfer operon, TraF, protein	-	-	-	-	-	-	-	-	-	-	-	-	TraF_2
k141_1341_2	675815.VOA_001595	2.16e-12	66.2	2BTFF@1|root,32NMR@2|Bacteria,1QJBY@1224|Proteobacteria,1THAZ@1236|Gammaproteobacteria,1XSXM@135623|Vibrionales	135623|Vibrionales	S	Protein of unknown function (DUF2861)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2861
k141_5045_3	945550.VISI1226_19167	1.94e-38	132.0	COG3013@1|root,COG3013@2|Bacteria,1QWV8@1224|Proteobacteria,1RME1@1236|Gammaproteobacteria,1XU0X@135623|Vibrionales	135623|Vibrionales	S	Belongs to the UPF0304 family	yfbU	-	-	ko:K09161	-	-	-	-	ko00000	-	-	-	YfbU
k141_5291_1	177437.HRM2_31930	3.87e-13	70.5	COG0236@1|root,COG0304@1|root,COG1028@1|root,COG2070@1|root,COG3321@1|root,COG0236@2|Bacteria,COG0304@2|Bacteria,COG1028@2|Bacteria,COG2070@2|Bacteria,COG3321@2|Bacteria,1R89Z@1224|Proteobacteria,42NGA@68525|delta/epsilon subdivisions,2WJK3@28221|Deltaproteobacteria,2MIK4@213118|Desulfobacterales	28221|Deltaproteobacteria	IQ	Beta-ketoacyl synthase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_1,KAsynt_C_assoc,KR,Ketoacyl-synt_C,NMO,PP-binding,PS-DH,ketoacyl-synt
k141_5291_3	177437.HRM2_06280	2.53e-204	573.0	COG1883@1|root,COG1883@2|Bacteria,1MV0G@1224|Proteobacteria,42MH1@68525|delta/epsilon subdivisions,2WJD7@28221|Deltaproteobacteria,2MIY0@213118|Desulfobacterales	28221|Deltaproteobacteria	C	TIGRFAM sodium ion-translocating decarboxylase, beta subunit	-	-	4.1.1.3	ko:K01572	ko00620,ko01100,map00620,map01100	-	R00217	RC00040	ko00000,ko00001,ko01000,ko02000	3.B.1.1.1	-	-	OAD_beta
k141_5046_1	1121004.ATVC01000024_gene236	1.82e-17	88.2	COG2199@1|root,COG3706@2|Bacteria,1RD8D@1224|Proteobacteria,2VS5N@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Diguanylate cyclase	-	-	2.7.7.65	ko:K21019	ko02025,map02025	-	-	-	ko00000,ko00001,ko01000	-	-	-	GGDEF
k141_3293_1	283699.D172_3955	1.24e-267	751.0	COG0210@1|root,COG0210@2|Bacteria,1MXV9@1224|Proteobacteria,1S9EG@1236|Gammaproteobacteria,2Q4U7@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	L	UvrD/REP helicase N-terminal domain	-	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AAA_19,UvrD-helicase,UvrD_C
k141_5292_1	1123274.KB899409_gene459	6.12e-92	279.0	COG4239@1|root,COG4239@2|Bacteria,2JAG7@203691|Spirochaetes	203691|Spirochaetes	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K13895	ko02010,map02010	M00349	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.21,3.A.1.5.24	-	-	BPD_transp_1,OppC_N
k141_1343_1	1345695.CLSA_c07390	3.57e-69	230.0	COG2199@1|root,COG4564@1|root,COG3706@2|Bacteria,COG4564@2|Bacteria,1V9Y7@1239|Firmicutes,24A8B@186801|Clostridia,36E8P@31979|Clostridiaceae	186801|Clostridia	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GGDEF,Pkinase,TPR_12,TPR_8
k141_1601_1	223926.28807992	4.69e-85	263.0	COG3274@1|root,COG3274@2|Bacteria,1MUJ6@1224|Proteobacteria,1S09B@1236|Gammaproteobacteria,1XT5S@135623|Vibrionales	135623|Vibrionales	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
k141_1601_2	1238450.VIBNISOn1_330008	5.97e-72	220.0	COG0783@1|root,COG0783@2|Bacteria,1RAC5@1224|Proteobacteria,1S3UH@1236|Gammaproteobacteria,1XWX7@135623|Vibrionales	135623|Vibrionales	P	Belongs to the Dps family	dps	-	-	ko:K04047	-	-	-	-	ko00000,ko03036	-	-	-	Ferritin
k141_1601_3	1219076.N646_2063	1.66e-218	611.0	COG0477@1|root,COG2814@2|Bacteria,1MV8D@1224|Proteobacteria,1RNF0@1236|Gammaproteobacteria,1XTRW@135623|Vibrionales	135623|Vibrionales	EGP	of the major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
k141_1601_4	1219080.VEZ01S_37_00210	8e-55	177.0	COG2453@1|root,COG2453@2|Bacteria,1N0H0@1224|Proteobacteria,1S9JV@1236|Gammaproteobacteria,1XWW6@135623|Vibrionales	135623|Vibrionales	T	phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	CDKN3,DSPc
k141_1601_5	945543.VIBR0546_08617	1.25e-191	537.0	COG0057@1|root,COG0057@2|Bacteria,1MU93@1224|Proteobacteria,1RMBM@1236|Gammaproteobacteria,1XV8J@135623|Vibrionales	135623|Vibrionales	C	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	gap	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
k141_941_2	1281779.H009_22063	1.2e-245	705.0	COG1419@1|root,COG1419@2|Bacteria,1R2A1@1224|Proteobacteria,2TZUK@28211|Alphaproteobacteria,4BK2J@82115|Rhizobiaceae	28211|Alphaproteobacteria	N	protein localization to endoplasmic reticulum	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_941_3	223926.28807124	1.63e-11	63.5	COG0582@1|root,COG0582@2|Bacteria,1N73Z@1224|Proteobacteria,1SEHI@1236|Gammaproteobacteria,1XTD7@135623|Vibrionales	135623|Vibrionales	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
k141_941_4	1205908.AKXW01000069_gene3545	9.23e-52	176.0	COG3344@1|root,COG3344@2|Bacteria,1MVI1@1224|Proteobacteria,1RMWW@1236|Gammaproteobacteria,1XSRZ@135623|Vibrionales	135623|Vibrionales	L	Group II intron, maturase-specific domain	-	-	2.7.7.49	ko:K00986	-	-	-	-	ko00000,ko01000	-	-	-	GIIM,RVT_1,RVT_N
k141_941_6	1517681.HW45_18405	3.67e-259	717.0	COG0814@1|root,COG0814@2|Bacteria,1N3PB@1224|Proteobacteria,1RQXP@1236|Gammaproteobacteria,1XW8G@135623|Vibrionales	135623|Vibrionales	E	Serine transporter	-	-	-	-	-	-	-	-	-	-	-	-	Trp_Tyr_perm
k141_941_7	1499968.TCA2_3312	6.67e-09	65.1	COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1V08K@1239|Firmicutes,4HAY7@91061|Bacilli,26V4B@186822|Paenibacillaceae	91061|Bacilli	T	COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18,Response_reg
k141_941_8	314292.VAS14_04018	5.54e-130	384.0	COG5438@1|root,COG5438@2|Bacteria,1MYCQ@1224|Proteobacteria,1S1SI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	YibE/F-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YibE_F
k141_941_9	314292.VAS14_04023	1.08e-190	546.0	COG1785@1|root,COG1785@2|Bacteria,1MXI2@1224|Proteobacteria,1RNG8@1236|Gammaproteobacteria,1XTK7@135623|Vibrionales	135623|Vibrionales	P	Belongs to the alkaline phosphatase family	-	-	3.1.3.1	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	M00126	R02135,R04620	RC00017	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	-	-	-	Alk_phosphatase
k141_941_10	1348635.BBJY01000003_gene3869	1.34e-117	350.0	COG0687@1|root,COG0687@2|Bacteria,1MUYW@1224|Proteobacteria,1RM7W@1236|Gammaproteobacteria,1XX29@135623|Vibrionales	135623|Vibrionales	E	Bacterial extracellular solute-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_8
k141_941_11	1348635.BBJY01000003_gene3870	9.31e-277	791.0	COG5001@1|root,COG5001@2|Bacteria,1PRV9@1224|Proteobacteria,1RZHM@1236|Gammaproteobacteria,1XW3X@135623|Vibrionales	135623|Vibrionales	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
k141_941_12	458817.Shal_3122	3.23e-53	172.0	COG3305@1|root,COG3305@2|Bacteria,1RKBI@1224|Proteobacteria,1S6AE@1236|Gammaproteobacteria,2QCRM@267890|Shewanellaceae	1236|Gammaproteobacteria	S	Predicted membrane protein (DUF2127)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2127
k141_941_13	674977.VMC_15120	0.0	917.0	COG0550@1|root,COG0550@2|Bacteria,1MUFZ@1224|Proteobacteria,1RN4X@1236|Gammaproteobacteria,1XUYY@135623|Vibrionales	135623|Vibrionales	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topB	GO:0003674,GO:0003824,GO:0003916,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016853,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360	5.99.1.2	ko:K03169	-	-	-	-	ko00000,ko01000,ko03032	-	-	-	Topoisom_bac,Toprim
k141_941_14	29495.EA26_16465	2.19e-64	197.0	COG0278@1|root,COG0278@2|Bacteria,1MZ4V@1224|Proteobacteria,1S640@1236|Gammaproteobacteria,1XXC2@135623|Vibrionales	135623|Vibrionales	C	Belongs to the glutaredoxin family. Monothiol subfamily	grxD	-	-	ko:K07390	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Glutaredoxin
k141_941_16	28229.ND2E_0896	6.4e-07	55.1	2BHAZ@1|root,32BCK@2|Bacteria,1QJ9Y@1224|Proteobacteria,1TH8K@1236|Gammaproteobacteria,2Q838@267889|Colwelliaceae	1236|Gammaproteobacteria	S	Ribosomal S4P (gammaproteobacterial)	-	-	-	-	-	-	-	-	-	-	-	-	Ribosomal_S4Pg
k141_941_17	1051646.VITU9109_20606	1.16e-63	204.0	COG1028@1|root,COG1028@2|Bacteria,1QJGM@1224|Proteobacteria,1THGE@1236|Gammaproteobacteria,1XVMG@135623|Vibrionales	135623|Vibrionales	IQ	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	VP2120	-	-	-	-	-	-	-	-	-	-	-	adh_short
k141_941_18	674977.VMC_12120	1.94e-108	321.0	COG2853@1|root,COG2853@2|Bacteria,1MVX0@1224|Proteobacteria,1RNPS@1236|Gammaproteobacteria,1XV65@135623|Vibrionales	135623|Vibrionales	M	COG2853 Surface lipoprotein	vacJ	-	-	ko:K04754	-	-	-	-	ko00000	-	-	-	MlaA
k141_941_19	1219076.N646_1328	1.51e-46	156.0	2ER47@1|root,33IPS@2|Bacteria,1NHAY@1224|Proteobacteria,1SH4T@1236|Gammaproteobacteria,1XX51@135623|Vibrionales	135623|Vibrionales	S	Protein of unknown function (DUF2802)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2802
k141_941_21	55601.VANGNB10_cI1872c	6.91e-105	317.0	COG0835@1|root,COG0835@2|Bacteria,1MYHY@1224|Proteobacteria,1S2TC@1236|Gammaproteobacteria,1XTG9@135623|Vibrionales	135623|Vibrionales	NT	Two component signalling adaptor domain	VP2226	-	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
k141_941_23	675813.VIB_000830	4.36e-202	567.0	COG2201@1|root,COG2201@2|Bacteria,1MWCN@1224|Proteobacteria,1RN67@1236|Gammaproteobacteria,1XU6C@135623|Vibrionales	135623|Vibrionales	NT	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR	cheB	GO:0003674,GO:0003824,GO:0006935,GO:0008150,GO:0008984,GO:0009605,GO:0016787,GO:0016788,GO:0040011,GO:0042221,GO:0042330,GO:0050896,GO:0051723,GO:0052689,GO:0140096	3.1.1.61,3.5.1.44	ko:K03412	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,Response_reg
k141_941_24	55601.VANGNB10_cI1875c	0.0	962.0	COG0643@1|root,COG2198@1|root,COG3266@1|root,COG0643@2|Bacteria,COG2198@2|Bacteria,COG3266@2|Bacteria,1MUAG@1224|Proteobacteria,1RMS6@1236|Gammaproteobacteria,1XT18@135623|Vibrionales	135623|Vibrionales	NT	COG0643 Chemotaxis protein histidine kinase and related kinases	cheA	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt
k141_941_25	1348635.BBJY01000007_gene196	1.08e-114	335.0	COG3143@1|root,COG3143@2|Bacteria,1NIV6@1224|Proteobacteria,1RNG2@1236|Gammaproteobacteria,1XURP@135623|Vibrionales	135623|Vibrionales	NT	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)	cheZ	-	-	ko:K03414	ko02030,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheZ
k141_941_26	243277.VC_2065	2.19e-83	246.0	COG0745@1|root,COG0745@2|Bacteria,1RDNP@1224|Proteobacteria,1S47I@1236|Gammaproteobacteria,1XWXK@135623|Vibrionales	135623|Vibrionales	KT	Transmits chemoreceptor signals to flagelllar motor components	cheY	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
k141_941_27	55601.VANGNB10_cI1878c	1.91e-152	431.0	COG1191@1|root,COG1191@2|Bacteria,1MWEU@1224|Proteobacteria,1RMKJ@1236|Gammaproteobacteria,1XSRM@135623|Vibrionales	135623|Vibrionales	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes	fliA	-	-	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	-	-	-	ko00000,ko00001,ko02035,ko03021	-	-	-	Sigma70_r2,Sigma70_r3,Sigma70_r4
k141_941_29	243277.VC_2068	8.19e-228	642.0	COG1419@1|root,COG1419@2|Bacteria,1MUQW@1224|Proteobacteria,1RMUU@1236|Gammaproteobacteria,1XTQT@135623|Vibrionales	135623|Vibrionales	N	Flagellar biosynthesis	flhF	-	-	ko:K02404	-	-	-	-	ko00000,ko02035	-	-	-	SRP54
k141_941_30	675815.VOA_002415	0.0	1160.0	COG1298@1|root,COG1298@2|Bacteria,1MUF3@1224|Proteobacteria,1RMSM@1236|Gammaproteobacteria,1XSJN@135623|Vibrionales	135623|Vibrionales	N	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin	flhA	-	-	ko:K02400	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	FHIPEP
k141_941_31	1280001.BAOA01000009_gene4135	2.75e-63	197.0	COG2062@1|root,COG2062@2|Bacteria,1NAAE@1224|Proteobacteria,1SAT1@1236|Gammaproteobacteria,1XXBT@135623|Vibrionales	135623|Vibrionales	T	Phosphohistidine phosphatase sixA	sixA	-	-	ko:K08296	-	-	-	-	ko00000,ko01000	-	-	-	His_Phos_1
k141_681_1	198628.Dda3937_00656	1.61e-96	295.0	COG2207@1|root,COG2207@2|Bacteria,1MUEM@1224|Proteobacteria,1T1VS@1236|Gammaproteobacteria,2JDXC@204037|Dickeya	1236|Gammaproteobacteria	K	AraC-type transcriptional regulator N-terminus	-	-	-	-	-	-	-	-	-	-	-	-	AraC_N,HTH_18
k141_1625_1	386415.NT01CX_2306	1.71e-48	164.0	COG0789@1|root,COG0789@2|Bacteria,1V1M9@1239|Firmicutes,24FUE@186801|Clostridia,36KVK@31979|Clostridiaceae	186801|Clostridia	K	Domain of unknown function (DUF1836)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1836
k141_1625_2	456320.Mvol_0341	1.38e-119	356.0	COG0530@1|root,arCOG02881@2157|Archaea,2XVHN@28890|Euryarchaeota,23QQ0@183939|Methanococci	183939|Methanococci	P	PFAM sodium calcium exchanger membrane region	-	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
k141_1625_3	386415.NT01CX_0667	1.26e-109	318.0	COG2310@1|root,COG2310@2|Bacteria,1TNZQ@1239|Firmicutes,24A3Y@186801|Clostridia,36GMM@31979|Clostridiaceae	186801|Clostridia	T	resistance protein	terD_2	-	-	ko:K05795	-	-	-	-	ko00000	-	-	-	TerD
k141_1625_4	929506.CbC4_2399	3.66e-108	315.0	COG2310@1|root,COG2310@2|Bacteria,1TNZQ@1239|Firmicutes,24DJD@186801|Clostridia,36W5A@31979|Clostridiaceae	186801|Clostridia	T	TerD domain	-	-	-	ko:K05795	-	-	-	-	ko00000	-	-	-	TerD
k141_1625_5	1121324.CLIT_4c00480	2.52e-87	262.0	COG2310@1|root,COG2310@2|Bacteria,1TR98@1239|Firmicutes,24FZM@186801|Clostridia,25RAF@186804|Peptostreptococcaceae	186801|Clostridia	T	TerD domain	yceC	-	-	-	-	-	-	-	-	-	-	-	TerD
k141_1625_6	1384057.CD33_08140	1.29e-113	343.0	COG2301@1|root,COG2301@2|Bacteria,1TSF2@1239|Firmicutes,4HCJB@91061|Bacilli,3IXS2@400634|Lysinibacillus	91061|Bacilli	G	Citrate lyase	-	-	-	-	-	-	-	-	-	-	-	-	C-C_Bond_Lyase
k141_1625_7	666686.B1NLA3E_14265	1.01e-74	247.0	COG0503@1|root,COG0503@2|Bacteria,1UZSF@1239|Firmicutes,4HD0V@91061|Bacilli,1ZCGS@1386|Bacillus	91061|Bacilli	F	Phosphoribosyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	PRTase_2,TRSP
k141_1625_8	265729.GS18_0216690	1.92e-136	400.0	COG1358@1|root,COG1358@2|Bacteria,1TP5Y@1239|Firmicutes,4HEBY@91061|Bacilli,1ZDV5@1386|Bacillus	91061|Bacilli	J	Phosphoribosyl transferase (PRTase)	-	-	-	-	-	-	-	-	-	-	-	-	PELOTA_1,PRTase_1
k141_1625_9	445973.CLOBAR_01777	5.72e-48	167.0	COG0561@1|root,COG0561@2|Bacteria,1V24C@1239|Firmicutes,24HGT@186801|Clostridia,25RKV@186804|Peptostreptococcaceae	186801|Clostridia	S	Sucrose-6F-phosphate phosphohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3,S6PP
k141_1625_10	1511.CLOST_2363	1.12e-179	507.0	COG1077@1|root,COG1077@2|Bacteria,1TP51@1239|Firmicutes,247RG@186801|Clostridia,25QKC@186804|Peptostreptococcaceae	186801|Clostridia	D	Cell shape determining protein, MreB Mrl family	mreB	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
k141_1625_11	1408422.JHYF01000024_gene3841	3.99e-100	308.0	COG4786@1|root,COG4786@2|Bacteria,1TRFQ@1239|Firmicutes,24C2V@186801|Clostridia,36GJU@31979|Clostridiaceae	186801|Clostridia	N	flagellar basal body	flgG	-	-	ko:K02392	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod,Flg_bbr_C
k141_1625_12	1286171.EAL2_c03020	2e-104	311.0	COG4786@1|root,COG4786@2|Bacteria,1TT5Z@1239|Firmicutes,248M9@186801|Clostridia,25VE3@186806|Eubacteriaceae	186801|Clostridia	N	Flagellar basal body rod FlgEFG protein C-terminal	flgG	-	-	ko:K02390,ko:K02392	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod,Flg_bbr_C
k141_1625_14	1301100.HG529419_gene3071	4.34e-81	243.0	COG0764@1|root,COG0764@2|Bacteria,1V6EX@1239|Firmicutes,24JAW@186801|Clostridia,36IPJ@31979|Clostridiaceae	186801|Clostridia	I	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs	fabZ	-	4.2.1.59	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121	RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FabA
k141_1625_15	272563.CD630_27800	1.03e-248	701.0	COG1109@1|root,COG1109@2|Bacteria,1TP2N@1239|Firmicutes,2481Y@186801|Clostridia,25T3U@186804|Peptostreptococcaceae	186801|Clostridia	G	Phosphoglucomutase/phosphomannomutase, C-terminal domain	pgcA	-	5.4.2.2,5.4.2.8	ko:K01835,ko:K01840	ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00114,M00549	R00959,R01057,R01818,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
k141_1625_16	1511.CLOST_2359	1.25e-79	251.0	COG0679@1|root,COG0679@2|Bacteria,1UY4N@1239|Firmicutes,24ACC@186801|Clostridia,25RPX@186804|Peptostreptococcaceae	186801|Clostridia	S	Membrane transport protein	-	-	-	ko:K07088	-	-	-	-	ko00000	-	-	-	Mem_trans
k141_1625_17	1286171.EAL2_c03070	1.75e-35	127.0	COG2426@1|root,COG2426@2|Bacteria,1V3UW@1239|Firmicutes,24HSW@186801|Clostridia,25WA3@186806|Eubacteriaceae	186801|Clostridia	S	small multi-drug export protein	-	-	-	-	-	-	-	-	-	-	-	-	Sm_multidrug_ex
k141_1625_18	1121324.CLIT_13c00680	5.05e-114	333.0	COG0037@1|root,COG0037@2|Bacteria,1TQ0Y@1239|Firmicutes,247RP@186801|Clostridia	186801|Clostridia	H	Belongs to the TtcA family	ttcA2	-	-	-	-	-	-	-	-	-	-	-	ATP_bind_3
k141_3146_20	1540257.JQMW01000013_gene1167	6.57e-58	185.0	2BREV@1|root,32KDP@2|Bacteria,1V8FF@1239|Firmicutes,25AY9@186801|Clostridia,36W6C@31979|Clostridiaceae	186801|Clostridia	S	Protein of unknown function (DUF2975)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2975
k141_3146_21	1499689.CCNN01000007_gene914	1.29e-30	109.0	COG3655@1|root,COG3655@2|Bacteria,1VESP@1239|Firmicutes,24QSQ@186801|Clostridia,36KI4@31979|Clostridiaceae	186801|Clostridia	K	Transcriptional regulator	-	-	-	ko:K07727	-	-	-	-	ko00000,ko03000	-	-	-	HTH_26
k141_2767_1	573370.DMR_29200	2.22e-07	58.9	COG0642@1|root,COG0642@2|Bacteria,1NXDJ@1224|Proteobacteria,43BMJ@68525|delta/epsilon subdivisions,2X7SQ@28221|Deltaproteobacteria,2MHF7@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,PAS_4,Response_reg,SBP_bac_3
k141_2767_2	1167006.UWK_00194	1.62e-85	266.0	COG0834@1|root,COG0834@2|Bacteria,1MWIK@1224|Proteobacteria,42QMD@68525|delta/epsilon subdivisions,2WKZH@28221|Deltaproteobacteria,2MN4K@213118|Desulfobacterales	28221|Deltaproteobacteria	ET	Bacterial extracellular solute-binding proteins, family 3	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_3
k141_481_2	1348635.BBJY01000022_gene1926	6.66e-179	502.0	COG0604@1|root,COG0604@2|Bacteria,1MV3W@1224|Proteobacteria,1RMHG@1236|Gammaproteobacteria,1XUG2@135623|Vibrionales	135623|Vibrionales	C	COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases	yhdH	-	-	ko:K19745	ko00640,ko01100,map00640,map01100	-	R00919	RC00095	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
k141_4136_3	675813.VIB_001388	8.78e-258	735.0	COG0076@1|root,COG0160@1|root,COG0076@2|Bacteria,COG0160@2|Bacteria,1MWUX@1224|Proteobacteria,1RQ8G@1236|Gammaproteobacteria,1XV42@135623|Vibrionales	135623|Vibrionales	E	COG0160 4-aminobutyrate aminotransferase and related aminotransferases	-	-	2.6.1.76,4.1.1.86	ko:K00836,ko:K13745	ko00260,ko01100,ko01120,ko01210,ko01230,map00260,map01100,map01120,map01210,map01230	M00033	R06977,R07650	RC00006,RC00062,RC00299	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3,Pyridoxal_deC
k141_4136_4	223926.28806934	2.9e-290	817.0	COG0076@1|root,COG0160@1|root,COG0076@2|Bacteria,COG0160@2|Bacteria,1MWUX@1224|Proteobacteria,1RQ8G@1236|Gammaproteobacteria,1XV42@135623|Vibrionales	135623|Vibrionales	E	COG0160 4-aminobutyrate aminotransferase and related aminotransferases	-	-	2.6.1.76,4.1.1.86	ko:K00836,ko:K13745	ko00260,ko01100,ko01120,ko01210,ko01230,map00260,map01100,map01120,map01210,map01230	M00033	R06977,R07650	RC00006,RC00062,RC00299	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3,Pyridoxal_deC
k141_4136_5	870967.VIS19158_13682	8.84e-189	534.0	COG3004@1|root,COG3004@2|Bacteria,1MW15@1224|Proteobacteria,1RNDE@1236|Gammaproteobacteria,1XT58@135623|Vibrionales	135623|Vibrionales	P	) H( ) antiporter that extrudes sodium in exchange for external protons	nhaA	GO:0003674,GO:0005215,GO:0005451,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008150,GO:0008324,GO:0015075,GO:0015077,GO:0015078,GO:0015081,GO:0015291,GO:0015297,GO:0015298,GO:0015299,GO:0015318,GO:0015385,GO:0015491,GO:0015672,GO:0022804,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0035725,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0098655,GO:0098660,GO:0098662,GO:0099516,GO:1902600	-	ko:K03313	-	-	-	-	ko00000,ko02000	2.A.33.1	-	-	Na_H_antiport_1
k141_3806_1	745411.B3C1_10782	0.0	2145.0	COG2373@1|root,COG2373@2|Bacteria,1MV7J@1224|Proteobacteria,1RNRY@1236|Gammaproteobacteria,1J8TQ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Alpha-2-Macroglobulin	-	-	-	ko:K06894	-	-	-	-	ko00000	-	-	-	A2M,A2M_N,A2M_N_2,MG1,Thiol-ester_cl
k141_3806_2	745411.B3C1_10787	0.0	1083.0	COG4953@1|root,COG4953@2|Bacteria,1MUA9@1224|Proteobacteria,1RMBV@1236|Gammaproteobacteria,1J87I@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	Penicillin binding protein transpeptidase domain	pbpC	-	2.4.1.129	ko:K05367	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	BiPBP_C,Transgly,Transpeptidase
k141_3806_3	945550.VISI1226_08399	9.7e-152	450.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,1XSE1@135623|Vibrionales	135623|Vibrionales	T	COG2202 FOG PAS PAC domain	-	-	-	-	-	-	-	-	-	-	-	-	MCPsignal,PAS_3
k141_3806_4	314292.VAS14_00911	4.5e-265	733.0	COG1760@1|root,COG1760@2|Bacteria,1MUZN@1224|Proteobacteria,1RMJZ@1236|Gammaproteobacteria,1XSZW@135623|Vibrionales	135623|Vibrionales	E	COG1760 L-serine deaminase	sdaA	-	4.3.1.17	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	-	R00220,R00590	RC00331,RC02600	ko00000,ko00001,ko01000	-	-	-	SDH_alpha,SDH_beta
k141_3806_5	223926.28806871	1.79e-247	686.0	COG0814@1|root,COG0814@2|Bacteria,1NQFA@1224|Proteobacteria,1RQ8Q@1236|Gammaproteobacteria,1XSJ0@135623|Vibrionales	135623|Vibrionales	E	serine transporter	sdaC	-	-	ko:K03837	-	-	-	-	ko00000,ko02000	2.A.42.2.1	-	-	Trp_Tyr_perm
k141_3806_6	1517681.HW45_26055	2.41e-122	353.0	COG2964@1|root,COG2964@2|Bacteria,1MU5K@1224|Proteobacteria,1RPDQ@1236|Gammaproteobacteria,1XSSD@135623|Vibrionales	135623|Vibrionales	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	HTH_22,PAS_6
k141_3806_8	1280001.BAOA01000007_gene4040	2.74e-194	544.0	COG2221@1|root,COG2221@2|Bacteria,1R5VR@1224|Proteobacteria,1RQN0@1236|Gammaproteobacteria,1XUBN@135623|Vibrionales	135623|Vibrionales	C	4Fe-4S dicluster domain	asrC	-	-	-	-	-	-	-	-	-	-	-	Fer4,NIR_SIR,NIR_SIR_ferr
k141_3806_9	1280001.BAOA01000007_gene4041	2.42e-129	374.0	COG0543@1|root,COG0543@2|Bacteria,1R6QZ@1224|Proteobacteria,1RNK9@1236|Gammaproteobacteria,1XV1V@135623|Vibrionales	135623|Vibrionales	C	Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B	asrB	-	-	-	-	-	-	-	-	-	-	-	DHODB_Fe-S_bind,FAD_binding_6,NAD_binding_1
k141_3806_10	1280001.BAOA01000007_gene4042	4.18e-163	466.0	COG1143@1|root,COG1143@2|Bacteria,1QVAQ@1224|Proteobacteria,1T4SQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_22
k141_3806_12	1217656.F964_01577	1.62e-77	240.0	COG3201@1|root,COG3201@2|Bacteria	2|Bacteria	H	nicotinamide mononucleotide transporter	pnuC	-	-	ko:K03811	-	-	-	-	ko00000,ko02000	4.B.1.1	-	-	NMN_transporter
k141_3806_13	1217656.F964_01576	2.86e-166	474.0	COG3172@1|root,COG3172@2|Bacteria,1PTBQ@1224|Proteobacteria,1TAF7@1236|Gammaproteobacteria,3NRZ8@468|Moraxellaceae	1236|Gammaproteobacteria	H	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_28
k141_3806_14	1348635.BBJY01000005_gene3179	3.49e-54	182.0	2CCA0@1|root,32RM3@2|Bacteria,1N3KF@1224|Proteobacteria,1S93D@1236|Gammaproteobacteria,1Y2ZW@135623|Vibrionales	135623|Vibrionales	S	FhuF 2Fe-2S C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	FhuF_C
k141_3806_15	675812.VHA_001614	1.51e-23	100.0	COG1943@1|root,COG1943@2|Bacteria,1MVUV@1224|Proteobacteria,1RNIV@1236|Gammaproteobacteria,1XTXM@135623|Vibrionales	135623|Vibrionales	L	COG1943 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_482_1	1248232.BANQ01000086_gene2767	1.29e-19	83.6	COG3027@1|root,COG3027@2|Bacteria,1NJEZ@1224|Proteobacteria,1SAG6@1236|Gammaproteobacteria,1XYD2@135623|Vibrionales	135623|Vibrionales	D	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division	zapA	-	-	ko:K09888	-	-	-	-	ko00000,ko03036	-	-	-	ZapA
k141_482_2	675816.VIA_003942	1.2e-77	238.0	COG3079@1|root,COG3079@2|Bacteria,1N7W0@1224|Proteobacteria,1SCPW@1236|Gammaproteobacteria,1XT2F@135623|Vibrionales	135623|Vibrionales	S	Belongs to the UPF0149 family	VV2847	-	-	ko:K09895	-	-	-	-	ko00000	-	-	-	UPF0149
k141_482_3	630626.EBL_c06690	1.12e-103	318.0	COG0654@1|root,COG0654@2|Bacteria,1MU6I@1224|Proteobacteria,1RMS3@1236|Gammaproteobacteria	1236|Gammaproteobacteria	CH	hydroxylase	ubiH	GO:0003674,GO:0003824,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008681,GO:0009058,GO:0009108,GO:0009314,GO:0009416,GO:0009628,GO:0009987,GO:0016491,GO:0016705,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0050896,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:1901576,GO:1901661,GO:1901663	-	ko:K03185,ko:K18800	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04987,R04989,R08768,R08773	RC00046,RC02670	ko00000,ko00001,ko00002,ko01000	-	-	iB21_1397.B21_02702,iECBD_1354.ECBD_0830,iECB_1328.ECB_02739,iECD_1391.ECD_02739,iEcHS_1320.EcHS_A3066	FAD_binding_3
k141_4514_1	338963.Pcar_2784	1.21e-44	167.0	COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,42MC0@68525|delta/epsilon subdivisions,2X5CV@28221|Deltaproteobacteria,43W2D@69541|Desulfuromonadales	68525|delta/epsilon subdivisions	P	ABC transporter	-	-	3.6.3.29	ko:K02017	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.8	-	-	ABC_tran,TOBE
k141_4514_2	1293054.HSACCH_00299	1.71e-68	221.0	COG1177@1|root,COG1177@2|Bacteria,1URBC@1239|Firmicutes,24801@186801|Clostridia,3WAZP@53433|Halanaerobiales	186801|Clostridia	E	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02053	ko02024,map02024	M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11	-	-	BPD_transp_1
k141_2771_10	1286171.EAL2_c08260	0.0	946.0	COG1217@1|root,COG1217@2|Bacteria,1TQ5Y@1239|Firmicutes,248EB@186801|Clostridia,25UUY@186806|Eubacteriaceae	186801|Clostridia	T	GTP-binding protein TypA	typA	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,EFG_II,GTP_EFTU,GTP_EFTU_D2
k141_2771_11	485918.Cpin_6785	3.78e-36	134.0	2EJ04@1|root,325K7@2|Bacteria,4P37X@976|Bacteroidetes	976|Bacteroidetes	S	Suppressor of fused protein (SUFU)	-	-	-	-	-	-	-	-	-	-	-	-	SUFU
k141_2771_12	1220589.CD32_08830	8.26e-62	196.0	COG1859@1|root,COG1859@2|Bacteria,1V49Y@1239|Firmicutes,4HHHZ@91061|Bacilli	91061|Bacilli	J	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase	kptA	-	-	ko:K07559	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PTS_2-RNA
k141_2771_15	608506.COB47_0918	7.61e-63	206.0	COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia,42FKH@68295|Thermoanaerobacterales	186801|Clostridia	N	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella	fliC	-	-	ko:K02406	ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flagellin_C,Flagellin_N
k141_2771_16	1007096.BAGW01000023_gene203	2.06e-33	128.0	COG3187@1|root,COG3187@2|Bacteria,1UMA9@1239|Firmicutes,25GDD@186801|Clostridia	186801|Clostridia	O	Heat shock protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_2771_17	103690.17135348	1.2e-91	279.0	COG2746@1|root,COG2746@2|Bacteria,1GHME@1117|Cyanobacteria,1HK71@1161|Nostocales	1117|Cyanobacteria	V	Aminoglycoside 3-N-acetyltransferase	-	-	2.3.1.81	ko:K00662	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	Antibiotic_NAT
k141_2771_19	1408439.JHXW01000001_gene1808	1.34e-314	891.0	COG0247@1|root,COG0493@1|root,COG0247@2|Bacteria,COG0493@2|Bacteria,37A5A@32066|Fusobacteria	32066|Fusobacteria	CE	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster	-	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_17,Fer4_20,Pyr_redox_2
k141_2771_20	1319815.HMPREF0202_01366	7.75e-134	390.0	COG0697@1|root,COG0697@2|Bacteria,37AUN@32066|Fusobacteria	32066|Fusobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
k141_2771_21	1121342.AUCO01000036_gene1045	3.16e-110	345.0	COG3284@1|root,COG3284@2|Bacteria,1VHQN@1239|Firmicutes,25EB0@186801|Clostridia,36UIY@31979|Clostridiaceae	186801|Clostridia	KQ	Sigma54 specific transcriptional regulator, Fis family	stc2	-	-	ko:K21405	-	-	-	-	ko00000,ko03000	-	-	-	GAF,HTH_8,PAS,PAS_9,Sigma54_activat
k141_3820_1	1348635.BBJY01000015_gene697	1.74e-150	438.0	COG3106@1|root,COG3106@2|Bacteria,1MX6E@1224|Proteobacteria,1RQ05@1236|Gammaproteobacteria,1XT2C@135623|Vibrionales	135623|Vibrionales	S	YcjX-like family, DUF463	ycjX	-	-	ko:K06918	-	-	-	-	ko00000	-	-	-	DUF463
k141_3820_2	29495.EA26_06950	3.23e-105	319.0	COG3768@1|root,COG3768@2|Bacteria,1MU8S@1224|Proteobacteria,1RND9@1236|Gammaproteobacteria,1XSBZ@135623|Vibrionales	135623|Vibrionales	S	membrane	ycjF	-	-	ko:K08990	-	-	-	-	ko00000	-	-	-	DUF697
k141_3820_3	55601.VANGNB10_cI1389c	1.92e-278	772.0	COG3283@1|root,COG3283@2|Bacteria,1QTS3@1224|Proteobacteria,1RNAI@1236|Gammaproteobacteria,1XSF4@135623|Vibrionales	135623|Vibrionales	K	COG3283 Transcriptional regulator of aromatic amino acids metabolism	tyrR	-	-	ko:K03721	-	-	-	-	ko00000,ko03000	-	-	-	PAS,PAS_8,Sigma54_activat
k141_3820_4	1348635.BBJY01000015_gene694	9.27e-83	250.0	COG1670@1|root,COG1670@2|Bacteria,1MVG4@1224|Proteobacteria,1RQPX@1236|Gammaproteobacteria,1XV1R@135623|Vibrionales	135623|Vibrionales	J	COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins	rimJ	-	2.3.1.128	ko:K03790	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_3
k141_3820_5	945543.VIBR0546_15301	1.91e-82	246.0	2AQ2U@1|root,31F7Z@2|Bacteria,1R8TD@1224|Proteobacteria,1S0VX@1236|Gammaproteobacteria,1XWZE@135623|Vibrionales	135623|Vibrionales	S	Protein of unknown function (DUF2947)	VV12273	-	-	-	-	-	-	-	-	-	-	-	DUF2947
k141_3820_6	701176.VIBRN418_10003	6.76e-19	79.3	COG2991@1|root,COG2991@2|Bacteria,1NI0R@1224|Proteobacteria,1SGJF@1236|Gammaproteobacteria,1XYXD@135623|Vibrionales	135623|Vibrionales	S	protein conserved in bacteria	-	-	-	ko:K05952	-	-	-	-	ko00000	-	-	-	NqrM
k141_3820_7	55601.VANGNB10_cI1223	2.58e-07	50.8	COG0454@1|root,COG0456@2|Bacteria,1N2EC@1224|Proteobacteria,1RS2A@1236|Gammaproteobacteria,1XXK0@135623|Vibrionales	135623|Vibrionales	K	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
k141_490_1	160860.XP_007350647.1	9.56e-14	78.2	COG0339@1|root,KOG2089@2759|Eukaryota,38SFI@33154|Opisthokonta,3NX1E@4751|Fungi,3UZUJ@5204|Basidiomycota,224SF@155619|Agaricomycetes,3H0RU@355688|Agaricomycetes incertae sedis	4751|Fungi	O	Peptidase family M3	PRD1	GO:0000322,GO:0000323,GO:0000324,GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005758,GO:0005773,GO:0005794,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009987,GO:0012505,GO:0016787,GO:0019538,GO:0031967,GO:0031970,GO:0031974,GO:0031975,GO:0034641,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043603,GO:0044237,GO:0044238,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0070011,GO:0070013,GO:0071704,GO:0140096,GO:1901564	3.4.24.37	ko:K01405,ko:K13726	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3
k141_491_2	177437.HRM2_14050	3.92e-71	221.0	COG1126@1|root,COG1126@2|Bacteria,1MU9Q@1224|Proteobacteria,42M0S@68525|delta/epsilon subdivisions,2WITR@28221|Deltaproteobacteria,2MICA@213118|Desulfobacterales	28221|Deltaproteobacteria	E	ABC transporter	-	-	3.6.3.21	ko:K02028,ko:K09972,ko:K10004,ko:K10038	ko02010,ko02020,map02010,map02020	M00227,M00230,M00232,M00236	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.3,3.A.1.3.17,3.A.1.3.18,3.A.1.3.19,3.A.1.3.2,3.A.1.3.4,3.A.1.3.7,3.A.1.3.8	-	-	ABC_tran
k141_2105_2	1219076.N646_1293	2.9e-162	457.0	COG0101@1|root,COG0101@2|Bacteria,1MUYI@1224|Proteobacteria,1RMK2@1236|Gammaproteobacteria,1XTDP@135623|Vibrionales	135623|Vibrionales	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
k141_2105_4	55601.VANGNB10_cI0872	2.42e-216	607.0	COG0285@1|root,COG0285@2|Bacteria,1MVCH@1224|Proteobacteria,1RMB0@1236|Gammaproteobacteria,1XSGS@135623|Vibrionales	135623|Vibrionales	H	Belongs to the folylpolyglutamate synthase family	folC	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_C,Mur_ligase_M
k141_2105_5	675814.VIC_001836	7.36e-82	247.0	COG3147@1|root,COG3147@2|Bacteria,1NGE3@1224|Proteobacteria,1SCGC@1236|Gammaproteobacteria,1XVJ5@135623|Vibrionales	135623|Vibrionales	S	protein conserved in bacteria	dedD	-	-	ko:K03749	-	-	-	-	ko00000	-	-	-	SPOR
k141_2105_6	29495.EA26_16755	1.66e-86	257.0	COG1286@1|root,COG1286@2|Bacteria,1NF4G@1224|Proteobacteria,1RQ58@1236|Gammaproteobacteria,1XSSE@135623|Vibrionales	135623|Vibrionales	S	membrane protein, required for colicin V production	cvpA	-	-	ko:K03558	-	-	-	-	ko00000	-	-	-	Colicin_V
k141_4146_1	519442.Huta_2730	1.5e-74	257.0	COG0531@1|root,arCOG00451@1|root,arCOG00009@2157|Archaea,arCOG00451@2157|Archaea,2XTX6@28890|Euryarchaeota,23S2B@183963|Halobacteria	183963|Halobacteria	E	amino acid	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease,AA_permease_2,Usp
k141_4857_1	1322246.BN4_12751	5.11e-224	635.0	COG3604@1|root,COG3604@2|Bacteria,1QTT3@1224|Proteobacteria,42Y69@68525|delta/epsilon subdivisions,2WJ5F@28221|Deltaproteobacteria,2M91P@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	PFAM sigma-54 factor interaction domain-containing protein	-	-	-	ko:K02584	ko02020,map02020	-	-	-	ko00000,ko00001,ko03000	-	-	-	GAF,GAF_2,HTH_8,Sigma54_activat
k141_492_1	247490.KSU1_C0282	1.72e-26	121.0	COG3829@1|root,COG4191@1|root,COG3829@2|Bacteria,COG4191@2|Bacteria,2J2QC@203682|Planctomycetes	203682|Planctomycetes	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_3,PAS_4
k141_1108_3	181119.XP_005534071.1	3.88e-105	337.0	KOG1179@1|root,KOG1179@2759|Eukaryota,38B7F@33154|Opisthokonta,3BA3X@33208|Metazoa,3CRF3@33213|Bilateria,483GM@7711|Chordata,48Y9M@7742|Vertebrata,4GP6K@8782|Aves	33208|Metazoa	I	Very long-chain acyl-CoA synthetase-like	SLC27A5	GO:0000038,GO:0001676,GO:0003674,GO:0003824,GO:0004467,GO:0005215,GO:0005319,GO:0005342,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0005789,GO:0005886,GO:0006082,GO:0006091,GO:0006629,GO:0006631,GO:0006638,GO:0006639,GO:0006641,GO:0006642,GO:0006694,GO:0006699,GO:0006810,GO:0006811,GO:0006820,GO:0006869,GO:0008028,GO:0008150,GO:0008152,GO:0008202,GO:0008206,GO:0008509,GO:0008514,GO:0008610,GO:0009058,GO:0009925,GO:0009987,GO:0010876,GO:0012505,GO:0015075,GO:0015245,GO:0015318,GO:0015645,GO:0015711,GO:0015718,GO:0015721,GO:0015849,GO:0015850,GO:0015908,GO:0015909,GO:0015911,GO:0016020,GO:0016021,GO:0016053,GO:0016323,GO:0016405,GO:0016874,GO:0016877,GO:0016878,GO:0017144,GO:0019752,GO:0022857,GO:0030176,GO:0031224,GO:0031227,GO:0031957,GO:0031984,GO:0032787,GO:0032991,GO:0033036,GO:0034220,GO:0042175,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044425,GO:0044432,GO:0044444,GO:0044446,GO:0044459,GO:0044464,GO:0044877,GO:0045178,GO:0046394,GO:0046486,GO:0046942,GO:0046943,GO:0046950,GO:0046951,GO:0047747,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071704,GO:0071944,GO:0072330,GO:0098590,GO:0098656,GO:0098827,GO:1901360,GO:1901362,GO:1901568,GO:1901570,GO:1901576,GO:1901615,GO:1901617,GO:1902001,GO:1902224,GO:1903825,GO:1905039	6.2.1.3,6.2.1.7	ko:K08746,ko:K08748,ko:K08749	ko00120,ko01100,ko03320,ko04146,ko04931,ko04976,map00120,map01100,map03320,map04146,map04931,map04976	M00104,M00106	R02794,R04507,R04580,R08733,R08738,R08743	RC00004,RC00014,RC00137	ko00000,ko00001,ko00002,ko01000,ko01004,ko02000	4.C.1.1,4.C.1.1.5,4.C.1.1.8	-	-	AMP-binding,AMP-binding_C
k141_2772_2	1304885.AUEY01000016_gene3047	2.16e-136	397.0	COG0618@1|root,COG0618@2|Bacteria,1N0JS@1224|Proteobacteria,42P1S@68525|delta/epsilon subdivisions,2WJV0@28221|Deltaproteobacteria,2MI7M@213118|Desulfobacterales	28221|Deltaproteobacteria	S	PFAM phosphoesterase RecJ domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DHH,DHHA1
k141_2772_3	797303.Natpe_1498	8.45e-22	98.2	COG1234@1|root,arCOG00500@2157|Archaea,2XTUD@28890|Euryarchaeota,23STE@183963|Halobacteria	183963|Halobacteria	S	COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III	-	-	3.1.26.11	ko:K00784	ko03013,map03013	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	Lactamase_B_2
k141_2772_4	702450.CUW_0655	5.92e-37	135.0	COG1648@1|root,COG1648@2|Bacteria,1VA2E@1239|Firmicutes	1239|Firmicutes	H	Siroheme synthase	cysG	-	1.3.1.76,4.99.1.4	ko:K02304	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03947	RC01012,RC01034	ko00000,ko00001,ko00002,ko01000	-	-	-	CysG_dimeriser,NAD_binding_7,Sirohm_synth_M
k141_2106_1	177437.HRM2_24720	1.66e-31	112.0	2E6FN@1|root,3312Z@2|Bacteria,1N6QM@1224|Proteobacteria,42V22@68525|delta/epsilon subdivisions,2WRF9@28221|Deltaproteobacteria,2MM34@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_2106_2	96561.Dole_1984	1.54e-90	279.0	COG3876@1|root,COG3876@2|Bacteria,1MX3S@1224|Proteobacteria,42N6K@68525|delta/epsilon subdivisions,2WKFH@28221|Deltaproteobacteria,2MI37@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF1343)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1343
k141_1455_2	556269.ACDQ01000001_gene1191	1.92e-22	91.3	COG1018@1|root,COG1018@2|Bacteria,1N6XY@1224|Proteobacteria	1224|Proteobacteria	C	Ferredoxin	yfaE	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006091,GO:0006124,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016491,GO:0019538,GO:0022900,GO:0030091,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0048037,GO:0051536,GO:0051537,GO:0051540,GO:0055114,GO:0071704,GO:1901564	-	ko:K11107	-	-	-	-	ko00000	-	-	-	Fer2
k141_1455_3	870967.VIS19158_10144	6.53e-13	66.2	COG2963@1|root,COG2963@2|Bacteria,1PGXN@1224|Proteobacteria,1TAR0@1236|Gammaproteobacteria,1XZAG@135623|Vibrionales	135623|Vibrionales	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Tnp_1
k141_1455_4	765913.ThidrDRAFT_0640	2.57e-92	280.0	COG2801@1|root,COG2801@2|Bacteria,1MVXQ@1224|Proteobacteria,1RR4F@1236|Gammaproteobacteria,1WXZW@135613|Chromatiales	135613|Chromatiales	L	PFAM integrase	-	-	-	-	-	-	-	-	-	-	-	-	HTH_21,rve
k141_1455_6	870967.VIS19158_02450	1.51e-116	337.0	COG3039@1|root,COG3039@2|Bacteria,1MXTN@1224|Proteobacteria,1RM94@1236|Gammaproteobacteria,1XVGA@135623|Vibrionales	135623|Vibrionales	L	User locus_tag	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_5
k141_2773_1	986075.CathTA2_0988	2.08e-14	80.5	COG2199@1|root,COG2199@2|Bacteria,1UQA9@1239|Firmicutes,4HBNE@91061|Bacilli	91061|Bacilli	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS_3,PAS_4,PAS_9
k141_495_1	177439.DP0910	6.57e-44	154.0	COG0328@1|root,COG3341@1|root,COG0328@2|Bacteria,COG3341@2|Bacteria,1RCZ1@1224|Proteobacteria,42SIR@68525|delta/epsilon subdivisions,2WPJY@28221|Deltaproteobacteria,2MPZM@213118|Desulfobacterales	28221|Deltaproteobacteria	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhA	-	3.1.26.4	ko:K03469	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	Cauli_VI,RNase_H
k141_4148_1	675806.VII_002209	1.56e-12	65.5	COG0551@1|root,COG0551@2|Bacteria,1RJ5B@1224|Proteobacteria,1S349@1236|Gammaproteobacteria,1XT3J@135623|Vibrionales	135623|Vibrionales	L	Zn-finger domain associated with topoisomerase type I	-	-	-	-	-	-	-	-	-	-	-	-	DUF2726
k141_4148_2	55601.VANGNB10_cI1498	1.84e-67	223.0	COG2199@1|root,COG3706@2|Bacteria,1Q1G1@1224|Proteobacteria,1RYSD@1236|Gammaproteobacteria,1XVS6@135623|Vibrionales	135623|Vibrionales	T	COG2199 FOG GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
k141_2774_2	214092.YPO2273	8.2e-33	120.0	COG1396@1|root,COG1396@2|Bacteria,1PA6X@1224|Proteobacteria,1SWEF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	Helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
k141_4858_3	55601.VANGNB10_cII0396	1.04e-100	305.0	28M95@1|root,2ZAN4@2|Bacteria,1R588@1224|Proteobacteria,1RQZF@1236|Gammaproteobacteria,1XWTR@135623|Vibrionales	135623|Vibrionales	S	Zinc dependent phospholipase C	-	-	-	-	-	-	-	-	-	-	-	-	Zn_dep_PLPC
k141_4858_4	1238450.VIBNISOn1_30083	4.04e-65	214.0	COG0477@1|root,COG2814@2|Bacteria,1MWWU@1224|Proteobacteria,1RN2I@1236|Gammaproteobacteria,1XW16@135623|Vibrionales	135623|Vibrionales	EGP	COG0477 Permeases of the major facilitator superfamily	-	-	-	ko:K03291	-	-	-	-	ko00000,ko02000	2.A.1.20	-	-	MFS_1
k141_1109_2	243277.VC_1388	1.3e-171	488.0	COG0095@1|root,COG0095@2|Bacteria,1N1T8@1224|Proteobacteria,1RMGI@1236|Gammaproteobacteria,1XW3C@135623|Vibrionales	135623|Vibrionales	H	Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes	lplA	GO:0003674,GO:0003824,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009987,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0016874,GO:0016879,GO:0016979,GO:0018130,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:0140096,GO:1901360,GO:1901362,GO:1901576	6.3.1.20	ko:K03800	ko00785,ko01100,map00785,map01100	-	R07770,R07771,R11143	RC00043,RC00070,RC00090,RC00992,RC02896	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB,Lip_prot_lig_C
k141_1109_3	403833.Pmob_1605	3.03e-74	238.0	COG0679@1|root,COG0679@2|Bacteria	2|Bacteria	S	auxin-activated signaling pathway	-	-	-	ko:K07088	-	-	-	-	ko00000	-	-	-	Mem_trans
k141_1110_1	644282.Deba_2837	1.08e-24	100.0	COG1846@1|root,COG1846@2|Bacteria,1NG00@1224|Proteobacteria	1224|Proteobacteria	K	PFAM regulatory protein, MarR	-	-	-	-	-	-	-	-	-	-	-	-	MarR
k141_4149_1	933262.AXAM01000007_gene2052	1.48e-62	222.0	COG0574@1|root,COG3848@1|root,COG0574@2|Bacteria,COG3848@2|Bacteria,1MU0R@1224|Proteobacteria,42MW3@68525|delta/epsilon subdivisions,2WIXV@28221|Deltaproteobacteria,2MIGX@213118|Desulfobacterales	28221|Deltaproteobacteria	GT	pyruvate phosphate dikinase	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PPDK_N
k141_1111_2	1123075.AUDP01000015_gene3360	2.46e-08	58.2	COG1476@1|root,COG1476@2|Bacteria,1V36C@1239|Firmicutes,24933@186801|Clostridia,3WGG3@541000|Ruminococcaceae	186801|Clostridia	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
k141_3823_1	177437.HRM2_16990	1.32e-70	244.0	COG0840@1|root,COG4564@1|root,COG0840@2|Bacteria,COG4564@2|Bacteria,1MU9B@1224|Proteobacteria,42KZR@68525|delta/epsilon subdivisions,2WJ2T@28221|Deltaproteobacteria,2MJ6B@213118|Desulfobacterales	28221|Deltaproteobacteria	NT	Cache_2	mcp40H-5	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal,dCache_2,sCache_2
k141_3823_2	315730.BcerKBAB4_1527	1.01e-21	99.0	COG0789@1|root,COG4978@1|root,COG0789@2|Bacteria,COG4978@2|Bacteria,1VDJC@1239|Firmicutes,4HKRX@91061|Bacilli,1ZEZ3@1386|Bacillus	91061|Bacilli	KT	helix_turn_helix, mercury resistance	-	-	-	-	-	-	-	-	-	-	-	-	GyrI-like,MerR_1
k141_3823_3	207559.Dde_3291	5.43e-135	390.0	COG0789@1|root,COG4978@1|root,COG0789@2|Bacteria,COG4978@2|Bacteria,1Q1J5@1224|Proteobacteria,42YU1@68525|delta/epsilon subdivisions,2WU2G@28221|Deltaproteobacteria,2MAMG@213115|Desulfovibrionales	28221|Deltaproteobacteria	K	transcriptional regulator, MerR	-	-	-	-	-	-	-	-	-	-	-	-	GyrI-like,MerR_1
k141_497_1	223926.28809282	5.47e-81	251.0	COG2704@1|root,COG2704@2|Bacteria,1MVHH@1224|Proteobacteria,1RPTE@1236|Gammaproteobacteria,1XT7X@135623|Vibrionales	135623|Vibrionales	S	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane	dcuB	-	-	ko:K07792	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.13.1	-	-	DcuA_DcuB
k141_497_3	1116375.VEJY3_20481	4.45e-194	551.0	COG1115@1|root,COG1115@2|Bacteria,1MUI3@1224|Proteobacteria,1RMNF@1236|Gammaproteobacteria,1XZXD@135623|Vibrionales	135623|Vibrionales	E	Sodium:alanine symporter family	-	-	-	ko:K03310	-	-	-	-	ko00000	2.A.25	-	-	Na_Ala_symp
k141_4859_1	1265505.ATUG01000001_gene3721	2.87e-242	671.0	COG0050@1|root,COG0050@2|Bacteria,1MVC0@1224|Proteobacteria,42MWZ@68525|delta/epsilon subdivisions,2WJ2B@28221|Deltaproteobacteria,2MHTQ@213118|Desulfobacterales	28221|Deltaproteobacteria	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
k141_498_1	55601.VANGNB10_cI0749c	6.42e-118	353.0	COG4623@1|root,COG4623@2|Bacteria,1MWDS@1224|Proteobacteria,1RM8W@1236|Gammaproteobacteria,1XTC4@135623|Vibrionales	135623|Vibrionales	M	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella	mltF	GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009253,GO:0009279,GO:0016020,GO:0019867,GO:0030203,GO:0030312,GO:0030313,GO:0031975,GO:0043170,GO:0044462,GO:0044464,GO:0071704,GO:0071944,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575	-	ko:K18691	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	SBP_bac_3,SLT
k141_2775_1	471874.PROSTU_01059	1.21e-47	158.0	COG3293@1|root,COG3293@2|Bacteria,1PG2J@1224|Proteobacteria,1TKWZ@1236|Gammaproteobacteria,3ZAA5@586|Providencia	1236|Gammaproteobacteria	L	COG3293 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_2775_2	471874.PROSTU_01059	2.23e-63	201.0	COG3293@1|root,COG3293@2|Bacteria,1PG2J@1224|Proteobacteria,1TKWZ@1236|Gammaproteobacteria,3ZAA5@586|Providencia	1236|Gammaproteobacteria	L	COG3293 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_2775_3	312309.VF_0977	2.19e-61	192.0	COG2153@1|root,COG2153@2|Bacteria,1MZ86@1224|Proteobacteria,1S8SK@1236|Gammaproteobacteria,1XXMX@135623|Vibrionales	135623|Vibrionales	S	FR47-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_10
k141_3660_4	1517681.HW45_26850	2.69e-79	246.0	2AVTF@1|root,31MKZ@2|Bacteria,1QJF7@1224|Proteobacteria,1THEK@1236|Gammaproteobacteria,1XUYF@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_3660_5	1517681.HW45_26855	1.69e-91	282.0	2AVXE@1|root,31MRD@2|Bacteria,1QJI7@1224|Proteobacteria,1THI9@1236|Gammaproteobacteria,1XW2G@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_3660_7	243277.VC_A0972	2.59e-188	536.0	COG0477@1|root,COG2814@2|Bacteria,1N0KT@1224|Proteobacteria,1RYZC@1236|Gammaproteobacteria,1XUY0@135623|Vibrionales	135623|Vibrionales	EGP	of the major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
k141_3660_8	1515746.HR45_06835	0.0	949.0	COG0754@1|root,COG0754@2|Bacteria,1MW6V@1224|Proteobacteria,1RQAP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Glutathionylspermidine synthase	gsp	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008884,GO:0008885,GO:0016787,GO:0016810,GO:0016811,GO:0016874,GO:0016879,GO:0016880,GO:0044424,GO:0044444,GO:0044464	3.5.1.78,6.3.1.8	ko:K01460	ko00480,ko01100,map00480,map01100	-	R01917,R01918	RC00090,RC00096	ko00000,ko00001,ko01000	-	-	iECIAI39_1322.ECIAI39_3484	CHAP,GSP_synth
k141_3660_9	1348635.BBJY01000005_gene3312	1.26e-239	686.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,1XSMX@135623|Vibrionales	135623|Vibrionales	NT	methyl-accepting chemotaxis protein	VP1088	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal
k141_1975_1	981336.F944_03084	1.23e-06	55.8	COG1121@1|root,COG1121@2|Bacteria,1MUDW@1224|Proteobacteria,1RPJT@1236|Gammaproteobacteria,3NJ9Z@468|Moraxellaceae	1236|Gammaproteobacteria	P	Part of the ABC transporter complex ZnuABC involved in zinc import. Responsible for energy coupling to the transport system	znuC	GO:0000041,GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005385,GO:0005488,GO:0005524,GO:0006810,GO:0006811,GO:0006812,GO:0006829,GO:0008144,GO:0008150,GO:0008324,GO:0015075,GO:0015318,GO:0015399,GO:0015405,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022890,GO:0030001,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0043167,GO:0043168,GO:0043492,GO:0046873,GO:0046915,GO:0051179,GO:0051234,GO:0055085,GO:0070838,GO:0071577,GO:0072509,GO:0072511,GO:0097159,GO:0097367,GO:0098655,GO:0098660,GO:0098662,GO:1901265,GO:1901363	-	ko:K09817	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.15.3,3.A.1.15.5	-	iSFV_1184.SFV_1859,iSF_1195.SF1867,iSFxv_1172.SFxv_2092,iS_1188.S1934	ABC_tran
k141_870_2	287.DR97_123	3.44e-25	109.0	COG3103@1|root,COG3103@2|Bacteria,1R4IV@1224|Proteobacteria,1RYIZ@1236|Gammaproteobacteria,1YF1T@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	T	Sh3 type 3 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Phenol_MetA_deg
k141_3661_2	102125.Xen7305DRAFT_00026490	3.1e-58	189.0	2DB8R@1|root,2Z7SP@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_3958_2	1348635.BBJY01000002_gene3406	0.0	1037.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,1RN2C@1236|Gammaproteobacteria,1XSZD@135623|Vibrionales	135623|Vibrionales	P	COG2217 Cation transport ATPase	copA	GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0051179,GO:0051234	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
k141_3958_3	1188252.AJYK01000092_gene1755	3.27e-59	197.0	COG3735@1|root,COG3735@2|Bacteria,1MVCW@1224|Proteobacteria,1RRI8@1236|Gammaproteobacteria,1XVUE@135623|Vibrionales	135623|Vibrionales	S	protein conserved in bacteria	-	-	-	ko:K09973	-	-	-	-	ko00000	-	-	-	TraB
k141_2542_2	617140.AJZE01000008_gene3477	3.8e-284	785.0	COG1070@1|root,COG1070@2|Bacteria,1MWS5@1224|Proteobacteria,1RP2G@1236|Gammaproteobacteria,1Y2M4@135623|Vibrionales	135623|Vibrionales	G	FGGY family of carbohydrate kinases, N-terminal domain	-	-	2.7.1.53	ko:K00880	ko00040,ko00053,map00040,map00053	-	R01901,R07127	RC00002,RC00017,RC00538	ko00000,ko00001,ko01000	-	-	-	FGGY_C,FGGY_N
k141_2542_3	575788.VS_II0138	3.56e-124	358.0	COG0269@1|root,COG0269@2|Bacteria,1QWE4@1224|Proteobacteria,1RRCI@1236|Gammaproteobacteria,1XVVU@135623|Vibrionales	135623|Vibrionales	G	Orotidine 5'-phosphate decarboxylase / HUMPS family	ulaD	-	4.1.1.85	ko:K03078	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	M00550	R07125	RC01721	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase
k141_2542_4	617140.AJZE01000008_gene3479	6.35e-142	405.0	COG1414@1|root,COG1414@2|Bacteria,1MUNW@1224|Proteobacteria,1RR06@1236|Gammaproteobacteria,1XU1E@135623|Vibrionales	135623|Vibrionales	K	helix_turn_helix isocitrate lyase regulation	kdgR	-	-	ko:K19333,ko:K21602	-	-	-	-	ko00000,ko03000	-	-	-	HTH_IclR,IclR
k141_2542_5	617140.AJZE01000008_gene3480	1.9e-179	503.0	COG3623@1|root,COG3623@2|Bacteria,1MWTD@1224|Proteobacteria,1RPT6@1236|Gammaproteobacteria,1XVJF@135623|Vibrionales	135623|Vibrionales	G	3-epimerase	-	-	5.1.3.22	ko:K03079	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	M00550	R03244	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	AP_endonuc_2
k141_3959_1	1415780.JPOG01000001_gene1176	1.6e-42	153.0	COG0077@1|root,COG0077@2|Bacteria,1MU60@1224|Proteobacteria,1RNRD@1236|Gammaproteobacteria,1X4R7@135614|Xanthomonadales	135614|Xanthomonadales	E	Prephenate dehydratase	pheA	-	4.2.1.51,5.4.99.5	ko:K14170	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R00691,R01373,R01715	RC00360,RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,CM_2,PDT
k141_3255_1	177437.HRM2_43630	2.28e-45	182.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42MXI@68525|delta/epsilon subdivisions,2WIX9@28221|Deltaproteobacteria,2MHVJ@213118|Desulfobacterales	28221|Deltaproteobacteria	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,Cache_3-Cache_2,HAMP,MCPsignal,PAS_3,dCache_1,sCache_2
k141_613_1	903818.KI912268_gene1268	1.81e-79	242.0	COG0450@1|root,COG0450@2|Bacteria	2|Bacteria	O	alkyl hydroperoxide reductase	prxU	-	1.11.1.15	ko:K03386	ko04214,map04214	-	-	-	ko00000,ko00001,ko01000,ko04147	-	-	-	1-cysPrx_C,AhpC-TSA
k141_613_2	575788.VS_3126	4.03e-87	261.0	COG0242@1|root,COG0242@2|Bacteria,1RA2P@1224|Proteobacteria,1S247@1236|Gammaproteobacteria,1XSD0@135623|Vibrionales	135623|Vibrionales	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def	GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008463,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
k141_613_4	416591.Tlet_1610	1.05e-12	70.1	COG1846@1|root,COG1846@2|Bacteria,2GDIG@200918|Thermotogae	200918|Thermotogae	K	PFAM regulatory protein, MarR	-	-	-	-	-	-	-	-	-	-	-	-	MarR
k141_613_5	998088.B565_0516	8.93e-90	284.0	COG0477@1|root,COG2814@2|Bacteria,1PATR@1224|Proteobacteria,1RZIX@1236|Gammaproteobacteria	1236|Gammaproteobacteria	EGP	arabinose efflux permease	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
k141_613_6	643562.Daes_0590	2.38e-54	174.0	COG1846@1|root,COG1846@2|Bacteria,1NG00@1224|Proteobacteria,4378Q@68525|delta/epsilon subdivisions,2X9IH@28221|Deltaproteobacteria,2MDZ2@213115|Desulfovibrionales	28221|Deltaproteobacteria	K	Iron dependent repressor, N-terminal DNA binding domain	-	-	-	-	-	-	-	-	-	-	-	-	MarR
k141_613_7	1232437.KL661990_gene423	2.35e-77	244.0	COG0803@1|root,COG0803@2|Bacteria,1MVW9@1224|Proteobacteria,42MBX@68525|delta/epsilon subdivisions,2WJYG@28221|Deltaproteobacteria,2MJBW@213118|Desulfobacterales	28221|Deltaproteobacteria	P	PFAM periplasmic solute binding protein	-	-	-	ko:K09815	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ZnuA
k141_613_8	1167006.UWK_01845	6.36e-54	182.0	COG1121@1|root,COG1121@2|Bacteria,1MUDW@1224|Proteobacteria,42NI8@68525|delta/epsilon subdivisions,2WKMZ@28221|Deltaproteobacteria,2MHMM@213118|Desulfobacterales	28221|Deltaproteobacteria	P	PFAM ABC transporter	-	-	-	ko:K09817	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ABC_tran
k141_613_9	1307761.L21SP2_0376	2.29e-101	304.0	COG1108@1|root,COG1108@2|Bacteria,2J798@203691|Spirochaetes	203691|Spirochaetes	P	ABC 3 transport family	-	-	-	ko:K09816	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ABC-3
k141_613_10	29495.EA26_05715	4.75e-90	270.0	COG1484@1|root,COG1484@2|Bacteria,1MVU2@1224|Proteobacteria,1RNUA@1236|Gammaproteobacteria,1XW6A@135623|Vibrionales	135623|Vibrionales	L	IstB-like ATP binding N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	IstB_IS21,IstB_IS21_ATP
k141_613_11	1348635.BBJY01000035_gene2208	1.12e-18	77.4	COG1484@1|root,COG1484@2|Bacteria,1MVU2@1224|Proteobacteria,1RNUA@1236|Gammaproteobacteria,1XW6A@135623|Vibrionales	135623|Vibrionales	L	IstB-like ATP binding N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	IstB_IS21,IstB_IS21_ATP
k141_613_12	1517681.HW45_03795	4.79e-49	171.0	COG5421@1|root,COG5421@2|Bacteria,1R25F@1224|Proteobacteria,1RZQP@1236|Gammaproteobacteria,1XV94@135623|Vibrionales	135623|Vibrionales	L	Domain of unknown function (DUF4277)	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DUF4277
k141_3960_1	357804.Ping_0094	2.84e-21	99.0	COG1281@1|root,COG1281@2|Bacteria,1MUMU@1224|Proteobacteria,1RMP3@1236|Gammaproteobacteria,2QHIH@267894|Psychromonadaceae	1236|Gammaproteobacteria	O	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress	hslO	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006950,GO:0006979,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0031647,GO:0036506,GO:0042026,GO:0042802,GO:0043167,GO:0043169,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050896,GO:0065007,GO:0065008	-	ko:K04083	-	-	-	-	ko00000,ko03110	-	-	-	HSP33
k141_4671_1	701176.VIBRN418_06301	5.07e-258	719.0	COG2721@1|root,COG2721@2|Bacteria,1MU9V@1224|Proteobacteria,1RP0M@1236|Gammaproteobacteria,1XW7T@135623|Vibrionales	135623|Vibrionales	G	COG2721 Altronate dehydratase	-	-	4.2.1.7	ko:K01685	ko00040,ko01100,map00040,map01100	M00631	R01540	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	-	GD_AH_C,SAF
k141_4671_2	675813.VIB_001629	9.87e-70	211.0	COG0537@1|root,COG0537@2|Bacteria,1RDCJ@1224|Proteobacteria,1S3QE@1236|Gammaproteobacteria,1XXB1@135623|Vibrionales	135623|Vibrionales	FG	COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases	hinT	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	HIT
k141_4671_3	617140.AJZE01000049_gene280	9.3e-145	429.0	COG3014@1|root,COG3014@2|Bacteria,1PD4S@1224|Proteobacteria,1RQ8Y@1236|Gammaproteobacteria,1XUG4@135623|Vibrionales	135623|Vibrionales	S	protein conserved in bacteria	-	-	-	ko:K09859	-	-	-	-	ko00000	-	-	-	-
k141_4671_4	1191299.AJYX01000067_gene3784	5.2e-24	95.5	COG5633@1|root,COG5633@2|Bacteria,1N0YQ@1224|Proteobacteria,1S20S@1236|Gammaproteobacteria,1XXI4@135623|Vibrionales	135623|Vibrionales	S	periplasmic lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	DUF1425
k141_871_1	1304885.AUEY01000004_gene1002	3.46e-216	616.0	COG0445@1|root,COG0445@2|Bacteria,1MU6F@1224|Proteobacteria,42KZC@68525|delta/epsilon subdivisions,2WJ31@28221|Deltaproteobacteria,2MJBM@213118|Desulfobacterales	28221|Deltaproteobacteria	D	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34	gidA	GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363	-	ko:K03495	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko03016,ko03036	-	-	-	GIDA,GIDA_assoc
k141_871_2	1232437.KL661988_gene295	5.98e-74	238.0	COG1242@1|root,COG1242@2|Bacteria,1MUYF@1224|Proteobacteria,42PX9@68525|delta/epsilon subdivisions,2WIPW@28221|Deltaproteobacteria,2MI53@213118|Desulfobacterales	28221|Deltaproteobacteria	S	PFAM Radical SAM domain protein	yhcC-1	-	-	ko:K07139	-	-	-	-	ko00000	-	-	-	Radical_SAM,Radical_SAM_C
k141_2543_1	96561.Dole_2615	6.87e-108	328.0	COG1070@1|root,COG1070@2|Bacteria,1MW4A@1224|Proteobacteria,42NDC@68525|delta/epsilon subdivisions,2WJTX@28221|Deltaproteobacteria,2MHVM@213118|Desulfobacterales	28221|Deltaproteobacteria	G	FGGY family of carbohydrate kinases, N-terminal domain	-	-	2.7.1.17	ko:K00854	ko00040,ko01100,map00040,map01100	M00014	R01639	RC00002,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	-	FGGY_C,FGGY_N
k141_2543_2	688269.Theth_1368	1.4e-213	611.0	COG0277@1|root,COG0277@2|Bacteria	2|Bacteria	C	FAD linked oxidase domain protein	-	-	2.5.1.26	ko:K00803,ko:K11472	ko00565,ko00630,ko01100,ko01110,ko01120,ko01130,ko04146,map00565,map00630,map01100,map01110,map01120,map01130,map04146	-	R00475,R04311	RC00020,RC00042,RC02886	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
k141_1977_1	1348635.BBJY01000016_gene3965	3.21e-268	745.0	COG1129@1|root,COG1129@2|Bacteria,1MU22@1224|Proteobacteria,1RMCH@1236|Gammaproteobacteria,1XY8T@135623|Vibrionales	135623|Vibrionales	G	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	3.6.3.17	ko:K02056	-	M00221	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.2	-	-	ABC_tran
k141_1977_2	1283284.AZUK01000001_gene1592	4.04e-160	458.0	COG1172@1|root,COG1172@2|Bacteria,1MUM6@1224|Proteobacteria,1RRCX@1236|Gammaproteobacteria,1Y4FN@135624|Aeromonadales	135624|Aeromonadales	G	Branched-chain amino acid transport system / permease component	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
k141_3666_1	1304885.AUEY01000001_gene3210	8.82e-35	125.0	COG0293@1|root,COG0293@2|Bacteria,1MW1C@1224|Proteobacteria,42T4F@68525|delta/epsilon subdivisions,2WP6B@28221|Deltaproteobacteria,2MJST@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit	ftsJ	-	2.1.1.166	ko:K02427	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ
k141_3666_2	1304885.AUEY01000049_gene1220	3.65e-176	508.0	COG1066@1|root,COG1066@2|Bacteria,1MUJQ@1224|Proteobacteria,42MG8@68525|delta/epsilon subdivisions,2WJWP@28221|Deltaproteobacteria,2MHZV@213118|Desulfobacterales	28221|Deltaproteobacteria	O	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function	radA	-	-	ko:K04485	-	-	-	-	ko00000,ko03400	-	-	-	AAA_25,ATPase,ChlI,Lon_C
k141_614_1	313603.FB2170_10551	2.97e-269	783.0	COG0841@1|root,COG0841@2|Bacteria,4NDZG@976|Bacteroidetes,1HX2H@117743|Flavobacteriia,2PHWK@252356|Maribacter	976|Bacteroidetes	V	Protein export membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k141_4972_1	1177181.T9A_02814	1.61e-41	155.0	COG2202@1|root,COG5001@1|root,COG2202@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1XHGD@135619|Oceanospirillales	135619|Oceanospirillales	T	signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_3,PAS_9
k141_2301_1	796620.VIBC2010_00185	2.16e-132	410.0	COG1444@1|root,COG1444@2|Bacteria,1NBA4@1224|Proteobacteria,1RPAM@1236|Gammaproteobacteria,1XT9I@135623|Vibrionales	135623|Vibrionales	J	Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP)	tmcA	GO:0000049,GO:0000154,GO:0002097,GO:0002101,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008080,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0022613,GO:0030490,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042274,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0051391,GO:0051392,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1904812,GO:1990882,GO:1990883,GO:1990884	2.3.1.193	ko:K06957	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF1726,GNAT_acetyltr_2,Helicase_RecD
k141_2301_2	672.VV93_v1c32680	6.39e-188	530.0	COG0687@1|root,COG0687@2|Bacteria,1MUYW@1224|Proteobacteria,1RM7W@1236|Gammaproteobacteria,1XUI9@135623|Vibrionales	135623|Vibrionales	P	Required for the activity of the bacterial periplasmic transport system of putrescine	-	-	-	ko:K11069	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	SBP_bac_8
k141_2301_3	672.VV93_v1c45530	2.05e-161	460.0	COG1475@1|root,COG1475@2|Bacteria,1NGXR@1224|Proteobacteria,1RNZ3@1236|Gammaproteobacteria,1XSQH@135623|Vibrionales	135623|Vibrionales	K	Belongs to the ParB family	VVA1695	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
k141_2301_4	675813.VIB_002548	2.48e-275	755.0	COG1192@1|root,COG1192@2|Bacteria,1NAJP@1224|Proteobacteria,1S2DK@1236|Gammaproteobacteria,1XSUA@135623|Vibrionales	135623|Vibrionales	D	COG1192 ATPases involved in chromosome partitioning	parA	-	-	-	-	-	-	-	-	-	-	-	AAA_31
k141_4973_1	1230342.CTM_21106	3.38e-12	73.2	COG0840@1|root,COG0840@2|Bacteria,1TP5A@1239|Firmicutes,247S3@186801|Clostridia,36EQK@31979|Clostridiaceae	186801|Clostridia	NT	chemotaxis	-	-	-	-	-	-	-	-	-	-	-	-	4HB_MCP_1,HAMP,MCPsignal,dCache_1
k141_4690_1	1187848.AJYQ01000076_gene1714	1.2e-148	426.0	COG0765@1|root,COG0765@2|Bacteria,1MV3I@1224|Proteobacteria,1RPJR@1236|Gammaproteobacteria,1XTN4@135623|Vibrionales	135623|Vibrionales	P	COG0765 ABC-type amino acid transport system, permease component	aapM	-	-	ko:K09971	ko02010,map02010	M00232	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3.18,3.A.1.3.7,3.A.1.3.8	-	-	BPD_transp_1
k141_4690_2	1348635.BBJY01000005_gene3292	5.12e-163	458.0	COG1126@1|root,COG1126@2|Bacteria,1MU9Q@1224|Proteobacteria,1RMX1@1236|Gammaproteobacteria,1XTEU@135623|Vibrionales	135623|Vibrionales	E	COG1126 ABC-type polar amino acid transport system, ATPase component	aapP	-	3.6.3.21	ko:K02028,ko:K09972	ko02010,map02010	M00232,M00236	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.3,3.A.1.3.17,3.A.1.3.18,3.A.1.3.7,3.A.1.3.8	-	-	ABC_tran
k141_632_1	933262.AXAM01000020_gene27	2.21e-07	52.0	COG0491@1|root,COG0491@2|Bacteria,1R4FA@1224|Proteobacteria,42TD1@68525|delta/epsilon subdivisions,2WPPD@28221|Deltaproteobacteria,2MQ1T@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
k141_632_2	338963.Pcar_2883	9.22e-50	164.0	COG3012@1|root,COG3012@2|Bacteria,1MZZK@1224|Proteobacteria,42RE5@68525|delta/epsilon subdivisions,2WNNI@28221|Deltaproteobacteria,43SGT@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	PFAM SEC-C motif domain protein	-	-	-	ko:K09858	-	-	-	-	ko00000	-	-	-	SEC-C
k141_632_3	1121405.dsmv_2713	6.92e-138	398.0	COG0024@1|root,COG0024@2|Bacteria,1MU99@1224|Proteobacteria,42MM5@68525|delta/epsilon subdivisions,2WJMN@28221|Deltaproteobacteria,2MIBA@213118|Desulfobacterales	28221|Deltaproteobacteria	J	TIGRFAM methionine aminopeptidase, type I	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24,SEC-C
k141_632_4	555779.Dthio_PD2405	2.48e-67	209.0	COG0693@1|root,COG0693@2|Bacteria,1MY0C@1224|Proteobacteria,42TPX@68525|delta/epsilon subdivisions,2WNCR@28221|Deltaproteobacteria,2MGWH@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	PFAM ThiJ PfpI	-	-	3.5.1.124	ko:K05520	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DJ-1_PfpI
k141_4974_1	643562.Daes_0344	6.04e-39	147.0	COG2199@1|root,COG5001@1|root,COG5002@1|root,COG3706@2|Bacteria,COG5001@2|Bacteria,COG5002@2|Bacteria,1MU2C@1224|Proteobacteria	1224|Proteobacteria	T	Diguanylate cyclase	-	-	2.7.7.65	ko:K21084	ko02026,map02026	-	-	-	ko00000,ko00001,ko01000	-	-	-	CHASE,GAF,GAF_2,GGDEF,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_8,PAS_9,SBP_bac_3,dCache_1
k141_4974_2	1238450.VIBNISOn1_1800010	1.98e-102	304.0	COG2243@1|root,COG2243@2|Bacteria,1MV3G@1224|Proteobacteria,1T9EJ@1236|Gammaproteobacteria,1Y0D2@135623|Vibrionales	135623|Vibrionales	H	Tetrapyrrole (Corrin/Porphyrin) Methylases	-	-	2.1.1.130,2.1.1.151	ko:K03394	ko00860,ko01100,map00860,map01100	-	R03948,R05808	RC00003,RC01035,RC01662	ko00000,ko00001,ko01000	-	-	-	TP_methylase
k141_3686_1	55601.VANGNB10_cII0693	2.91e-174	511.0	COG1289@1|root,COG1289@2|Bacteria,1MWR1@1224|Proteobacteria,1RNIJ@1236|Gammaproteobacteria,1XTGG@135623|Vibrionales	135623|Vibrionales	S	membrane	yccS	-	-	-	-	-	-	-	-	-	-	-	FUSC-like,FUSC_2
k141_3686_2	1348635.BBJY01000014_gene861	3.09e-241	687.0	COG0210@1|root,COG0210@2|Bacteria,1MVWI@1224|Proteobacteria,1RN1N@1236|Gammaproteobacteria,1XTAF@135623|Vibrionales	135623|Vibrionales	L	COG0210 Superfamily I DNA and RNA helicases	helD	-	3.6.4.12	ko:K03658	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	Helicase_IV_N,UvrD-helicase,UvrD_C
k141_2879_1	55601.VANGNB10_cI0569	1.62e-271	764.0	COG3605@1|root,COG3605@2|Bacteria,1QTTV@1224|Proteobacteria,1T1H2@1236|Gammaproteobacteria,1XSXI@135623|Vibrionales	135623|Vibrionales	T	Belongs to the PEP-utilizing enzyme family	ptsP	-	2.7.3.9	ko:K08484	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	-	-	-	GAF,PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C
k141_2879_2	675815.VOA_003178	2.16e-122	356.0	COG0730@1|root,COG0730@2|Bacteria,1R3V4@1224|Proteobacteria,1RVNC@1236|Gammaproteobacteria,1XUH0@135623|Vibrionales	135623|Vibrionales	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
k141_2879_3	55601.VANGNB10_cI0571	1.37e-161	456.0	COG0682@1|root,COG0682@2|Bacteria,1MVE3@1224|Proteobacteria,1RMVK@1236|Gammaproteobacteria,1XSP4@135623|Vibrionales	135623|Vibrionales	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
k141_2302_2	720554.Clocl_3954	7.54e-64	222.0	COG3420@1|root,COG3420@2|Bacteria,1UY76@1239|Firmicutes,24JKT@186801|Clostridia	186801|Clostridia	P	Right handed beta helix region	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
k141_1556_1	177437.HRM2_03050	9.43e-113	331.0	COG1028@1|root,COG1028@2|Bacteria,1MWGC@1224|Proteobacteria,42QH3@68525|delta/epsilon subdivisions,2WKXH@28221|Deltaproteobacteria,2MJC1@213118|Desulfobacterales	28221|Deltaproteobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
k141_1556_2	177437.HRM2_03030	5.3e-158	454.0	COG3173@1|root,COG3173@2|Bacteria,1MWAK@1224|Proteobacteria,42PQ6@68525|delta/epsilon subdivisions,2WJHR@28221|Deltaproteobacteria,2MJ66@213118|Desulfobacterales	28221|Deltaproteobacteria	S	PFAM aminoglycoside phosphotransferase	-	-	-	-	-	-	-	-	-	-	-	-	APH
k141_1556_3	177437.HRM2_03020	1.31e-85	261.0	COG1309@1|root,COG1309@2|Bacteria,1RCC8@1224|Proteobacteria,42R6Y@68525|delta/epsilon subdivisions,2WN1T@28221|Deltaproteobacteria,2MJPC@213118|Desulfobacterales	28221|Deltaproteobacteria	K	PFAM regulatory protein TetR	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
k141_1556_4	177437.HRM2_03010	2.77e-140	405.0	COG1960@1|root,COG1960@2|Bacteria,1MU2V@1224|Proteobacteria,42NKV@68525|delta/epsilon subdivisions,2WKPA@28221|Deltaproteobacteria,2MIDW@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Acyl-CoA dehydrogenase, C-terminal domain	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
k141_3687_2	1284680.HMPREF1627_00100	6.03e-08	58.5	COG0584@1|root,COG0584@2|Bacteria,2GNM5@201174|Actinobacteria,4D3J7@85005|Actinomycetales	201174|Actinobacteria	C	glycerophosphodiester phosphodiesterase	glpQ	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
k141_633_1	1123020.AUIE01000016_gene1943	7.97e-18	78.2	COG2161@1|root,COG2161@2|Bacteria,1N0MZ@1224|Proteobacteria,1SA1X@1236|Gammaproteobacteria	1236|Gammaproteobacteria	D	Antitoxin component of a toxin-antitoxin (TA) module	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
k141_633_4	104623.Ser39006_00952	4.97e-47	159.0	2BVW3@1|root,2Z7TB@2|Bacteria,1MY60@1224|Proteobacteria,1RNI9@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	5'-nucleotidase	-	-	3.1.3.5	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	5-nucleotidase
k141_3980_1	675813.VIB_001756	1.54e-44	152.0	COG0780@1|root,COG2904@1|root,COG0780@2|Bacteria,COG2904@2|Bacteria,1MW0M@1224|Proteobacteria,1RNXM@1236|Gammaproteobacteria,1XSYX@135623|Vibrionales	135623|Vibrionales	S	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)	queF	-	1.7.1.13	ko:K06879	ko00790,ko01100,map00790,map01100	-	R07605	RC01875	ko00000,ko00001,ko01000,ko03016	-	-	-	QueF,QueF_N
k141_3980_2	1219080.VEZ01S_01_01370	1.13e-62	199.0	28Q4G@1|root,2ZCMR@2|Bacteria,1RAB3@1224|Proteobacteria,1S2N3@1236|Gammaproteobacteria,1XVSC@135623|Vibrionales	135623|Vibrionales	S	Interacts with the SecY protein in vivo. May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function	syd	-	-	ko:K15723	-	-	-	-	ko00000	-	-	-	Syd
k141_3980_3	1219065.VPR01S_18_01120	9.13e-165	463.0	COG5595@1|root,COG5595@2|Bacteria,1NDR3@1224|Proteobacteria,1RRXG@1236|Gammaproteobacteria,1XTPF@135623|Vibrionales	135623|Vibrionales	S	COG5595 Zn-ribbon-containing, possibly nucleic-acid-binding protein	HD1486	-	-	-	-	-	-	-	-	-	-	-	DUF2310
k141_3980_7	675816.VIA_003716	1.05e-118	340.0	COG0241@1|root,COG0241@2|Bacteria,1RDGR@1224|Proteobacteria,1S3UD@1236|Gammaproteobacteria,1XUHV@135623|Vibrionales	135623|Vibrionales	E	D,D-heptose 1,7-bisphosphate phosphatase	gmhB	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0034200,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914	3.1.3.82,3.1.3.83	ko:K03273	ko00540,ko01100,map00540,map01100	M00064	R05647,R09771	RC00017	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hydrolase_like
k141_3980_8	1348635.BBJY01000037_gene38	8.65e-14	69.3	2DPZZ@1|root,3345G@2|Bacteria,1N8ZZ@1224|Proteobacteria,1T6AC@1236|Gammaproteobacteria,1XZA4@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_3980_9	715451.ambt_15745	2.67e-48	164.0	COG1284@1|root,COG1284@2|Bacteria,1RDIV@1224|Proteobacteria,1RSIN@1236|Gammaproteobacteria,466KA@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Uncharacterised 5xTM membrane BCR, YitT family COG1284	VM57_04575	-	-	-	-	-	-	-	-	-	-	-	YitT_membrane
k141_875_1	1121396.KB893080_gene915	1.57e-144	428.0	COG1154@1|root,COG1154@2|Bacteria,1MUSJ@1224|Proteobacteria,42M35@68525|delta/epsilon subdivisions,2WIX5@28221|Deltaproteobacteria,2MI30@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)	dxs	-	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	-	DXP_synthase_N,Transket_pyr,Transketolase_C
k141_875_2	886293.Sinac_7456	5.99e-81	255.0	COG0142@1|root,COG0142@2|Bacteria,2IX56@203682|Planctomycetes	203682|Planctomycetes	H	Belongs to the FPP GGPP synthase family	-	-	2.5.1.1,2.5.1.10,2.5.1.29	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00366	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
k141_875_3	1280692.AUJL01000007_gene1379	1.38e-07	51.2	COG1722@1|root,COG1722@2|Bacteria	2|Bacteria	L	exodeoxyribonuclease VII activity	xseB	-	3.1.11.6	ko:K03602	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_S
k141_875_4	373903.Hore_06490	1.51e-89	285.0	COG1570@1|root,COG1570@2|Bacteria,1TP4E@1239|Firmicutes,247KE@186801|Clostridia,3WBC7@53433|Halanaerobiales	186801|Clostridia	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseA	-	3.1.11.6	ko:K03601	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
k141_1557_1	748280.NH8B_1509	1.79e-17	81.3	COG2201@1|root,COG2201@2|Bacteria,1MWCN@1224|Proteobacteria,2VI13@28216|Betaproteobacteria,2KQ0T@206351|Neisseriales	206351|Neisseriales	NT	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR	cheB	-	3.1.1.61,3.5.1.44	ko:K03412	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,Response_reg
k141_1557_2	626887.J057_07671	1.58e-72	228.0	COG1352@1|root,COG1352@2|Bacteria,1MU6W@1224|Proteobacteria,1RMFK@1236|Gammaproteobacteria,46564@72275|Alteromonadaceae	1236|Gammaproteobacteria	NT	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP	-	-	2.1.1.80	ko:K00575	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheR,CheR_N
k141_2881_2	1219080.VEZ01S_09_00120	3.99e-64	197.0	COG1733@1|root,COG1733@2|Bacteria,1N0WG@1224|Proteobacteria,1SAQU@1236|Gammaproteobacteria,1Y1BX@135623|Vibrionales	135623|Vibrionales	K	HxlR-like helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HxlR
k141_2881_3	314292.VAS14_13034	2.86e-30	108.0	COG2350@1|root,COG2350@2|Bacteria,1N8AZ@1224|Proteobacteria,1SE4K@1236|Gammaproteobacteria,1XZ4T@135623|Vibrionales	135623|Vibrionales	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
k141_4975_2	1304885.AUEY01000016_gene3076	1.57e-119	360.0	2DBWA@1|root,2ZBFZ@2|Bacteria,1R8CD@1224|Proteobacteria,42MWX@68525|delta/epsilon subdivisions,2WK78@28221|Deltaproteobacteria,2MHSB@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Alginate_exp
k141_4299_1	617140.AJZE01000014_gene1022	1.48e-259	716.0	COG0306@1|root,COG0306@2|Bacteria,1MVXK@1224|Proteobacteria,1RP0Q@1236|Gammaproteobacteria,1XU56@135623|Vibrionales	135623|Vibrionales	P	COG0306 Phosphate sulphate permeases	pitA	-	-	ko:K03306	-	-	-	-	ko00000	2.A.20	-	-	PHO4
k141_4299_2	1219065.VPR01S_21_00460	1.36e-97	288.0	COG3103@1|root,COG4991@2|Bacteria,1MX7M@1224|Proteobacteria,1RS74@1236|Gammaproteobacteria,1XUUZ@135623|Vibrionales	135623|Vibrionales	T	SH3 domain protein	htrG	-	-	ko:K07184	-	-	-	-	ko00000	-	-	-	SH3_3
k141_4494_2	1304888.ATWF01000001_gene1723	1.43e-128	375.0	COG4977@1|root,COG4977@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	DJ-1_PfpI,HTH_18
k141_1442_1	1173029.JH980292_gene2348	4.79e-126	414.0	COG0515@1|root,COG3899@1|root,COG4191@1|root,COG0515@2|Bacteria,COG3899@2|Bacteria,COG4191@2|Bacteria,1GBKM@1117|Cyanobacteria,1H7D9@1150|Oscillatoriales	1117|Cyanobacteria	KLT	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GAF,HATPase_c,HisKA,PAS_4,Pkinase
k141_3801_1	879212.DespoDRAFT_03141	6.05e-20	94.0	COG2091@1|root,COG2091@2|Bacteria,1MZHC@1224|Proteobacteria,42SJT@68525|delta/epsilon subdivisions,2WP3F@28221|Deltaproteobacteria,2MKBG@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Belongs to the P-Pant transferase superfamily	-	-	-	ko:K06133	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	-	ACPS
k141_3801_2	262543.Exig_0394	6.38e-06	49.7	COG1024@1|root,COG1024@2|Bacteria,1TQ89@1239|Firmicutes,4HBW0@91061|Bacilli	91061|Bacilli	I	Belongs to the enoyl-CoA hydratase isomerase family	paaF	-	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
k141_5146_1	879212.DespoDRAFT_00822	7.4e-111	330.0	COG0065@1|root,COG0065@2|Bacteria,1MVYR@1224|Proteobacteria,42M5D@68525|delta/epsilon subdivisions,2WJ59@28221|Deltaproteobacteria,2MHP1@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuC	-	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase
k141_4514_3	1301100.HG529399_gene6834	1.93e-51	177.0	COG1176@1|root,COG1176@2|Bacteria,1V1K7@1239|Firmicutes,24A4Q@186801|Clostridia,36GH7@31979|Clostridiaceae	186801|Clostridia	P	inner membrane component	-	-	-	ko:K02054	ko02024,map02024	M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11	-	-	BPD_transp_1
k141_4514_4	768710.DesyoDRAFT_2623	2.15e-140	414.0	COG4134@1|root,COG4134@2|Bacteria,1TR3G@1239|Firmicutes,24A5K@186801|Clostridia,2640Y@186807|Peptococcaceae	186801|Clostridia	S	Bacterial extracellular solute-binding protein	-	-	-	ko:K02055	ko02024,map02024	M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11	-	-	SBP_bac_8
k141_4514_5	1476973.JMMB01000007_gene1668	1.55e-60	194.0	COG0558@1|root,COG0558@2|Bacteria,1V33A@1239|Firmicutes,24G6W@186801|Clostridia,25TDP@186804|Peptostreptococcaceae	186801|Clostridia	I	CDP-alcohol phosphatidyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	CDP-OH_P_transf
k141_4514_6	555079.Toce_0088	2.77e-60	196.0	COG0398@1|root,COG0398@2|Bacteria,1UHVT@1239|Firmicutes,24H7Q@186801|Clostridia	186801|Clostridia	S	PFAM SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
k141_4514_8	1150474.JQJI01000004_gene366	3.59e-27	124.0	COG2199@1|root,COG3706@2|Bacteria,2GCEU@200918|Thermotogae	200918|Thermotogae	T	PFAM GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
k141_2768_1	1121405.dsmv_3263	0.0	976.0	COG0525@1|root,COG0525@2|Bacteria,1MV7B@1224|Proteobacteria,42MPZ@68525|delta/epsilon subdivisions,2WIR9@28221|Deltaproteobacteria,2MHQG@213118|Desulfobacterales	28221|Deltaproteobacteria	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
k141_2768_2	96561.Dole_1728	7.73e-87	267.0	COG0157@1|root,COG0157@2|Bacteria,1MW0C@1224|Proteobacteria,42MY7@68525|delta/epsilon subdivisions,2WJH7@28221|Deltaproteobacteria,2MIBN@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Belongs to the NadC ModD family	nadC	-	2.4.2.19	ko:K00767	ko00760,ko01100,map00760,map01100	M00115	R03348	RC02877	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1988	QRPTase_C,QRPTase_N
k141_1087_1	744872.Spica_0213	5.79e-20	91.7	COG2197@1|root,COG2197@2|Bacteria,2JAGN@203691|Spirochaetes	203691|Spirochaetes	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
k141_1087_2	349521.HCH_03563	2.34e-119	363.0	28M1K@1|root,2ZAGC@2|Bacteria,1R54U@1224|Proteobacteria,1S1SJ@1236|Gammaproteobacteria,1XNPE@135619|Oceanospirillales	135619|Oceanospirillales	S	Aerolysin toxin	-	-	-	-	-	-	-	-	-	-	-	-	Aerolysin
k141_1087_3	1121935.AQXX01000114_gene3231	4.12e-94	298.0	28M1K@1|root,2ZAGC@2|Bacteria,1R54U@1224|Proteobacteria,1S1SJ@1236|Gammaproteobacteria,1XNPE@135619|Oceanospirillales	135619|Oceanospirillales	S	Aerolysin toxin	-	-	-	-	-	-	-	-	-	-	-	-	Aerolysin
k141_1087_5	269798.CHU_2580	6.99e-13	73.6	COG4330@1|root,COG4330@2|Bacteria,4NNT4@976|Bacteroidetes,47PCZ@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF1361)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1361
k141_1087_9	3218.PP1S52_142V6.1	2.65e-05	50.8	COG0456@1|root,KOG3138@2759|Eukaryota,37IRZ@33090|Viridiplantae,3GDKY@35493|Streptophyta	35493|Streptophyta	S	N-alpha-acetyltransferase	-	GO:0000070,GO:0000278,GO:0000280,GO:0000819,GO:0003674,GO:0003824,GO:0004402,GO:0004596,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005829,GO:0006325,GO:0006464,GO:0006473,GO:0006474,GO:0006475,GO:0006807,GO:0006996,GO:0007049,GO:0007059,GO:0007062,GO:0007064,GO:0008080,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0010485,GO:0016043,GO:0016407,GO:0016410,GO:0016569,GO:0016570,GO:0016573,GO:0016740,GO:0016746,GO:0016747,GO:0018193,GO:0018205,GO:0018393,GO:0018394,GO:0019538,GO:0022402,GO:0031365,GO:0034085,GO:0034087,GO:0034212,GO:0036211,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043412,GO:0043543,GO:0043967,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0048285,GO:0051276,GO:0051604,GO:0052858,GO:0061733,GO:0070601,GO:0071704,GO:0071840,GO:0071962,GO:0098813,GO:0140014,GO:1901564,GO:1903047	2.3.1.258	ko:K20793	-	-	-	-	ko00000,ko01000,ko03036	-	-	-	Acetyltransf_1
k141_1087_10	1120998.AUFC01000015_gene1589	3.31e-48	165.0	COG1647@1|root,COG1647@2|Bacteria,1TQ7X@1239|Firmicutes,24HZH@186801|Clostridia	186801|Clostridia	S	Serine aminopeptidase, S33	-	-	3.1.1.1	ko:K03928	-	-	-	-	ko00000,ko01000	-	-	-	Hydrolase_4
k141_1087_11	431943.CKL_2492	5.89e-31	118.0	COG1309@1|root,COG1309@2|Bacteria,1U9UE@1239|Firmicutes,24F64@186801|Clostridia,36W0I@31979|Clostridiaceae	186801|Clostridia	K	WHG domain	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N,WHG
k141_4137_1	1348635.BBJY01000003_gene3925	5.12e-159	451.0	COG0115@1|root,COG0115@2|Bacteria,1MVAT@1224|Proteobacteria,1RPU0@1236|Gammaproteobacteria,1XYS3@135623|Vibrionales	135623|Vibrionales	EH	Amino-transferase class IV	-	-	2.6.1.21	ko:K00824	ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100	-	R01148,R01582,R02459,R02851,R02924,R05053	RC00006,RC00008,RC00025	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_4
k141_4137_2	595494.Tola_0562	1.47e-143	415.0	COG4948@1|root,COG4948@2|Bacteria,1MW76@1224|Proteobacteria,1RMKS@1236|Gammaproteobacteria,1Y68J@135624|Aeromonadales	135624|Aeromonadales	M	Mandelate racemase / muconate lactonizing enzyme, N-terminal domain	-	-	5.1.1.20,5.5.1.1	ko:K01856,ko:K19802	ko00361,ko00362,ko00364,ko00623,ko01100,ko01120,ko01220,map00361,map00362,map00364,map00623,map01100,map01120,map01220	M00568	R05300,R05390,R06989,R08116,R09229,R10938	RC00903,RC01038,RC01108,RC01321,RC01356,RC03309	ko00000,ko00001,ko00002,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
k141_4137_3	1348635.BBJY01000003_gene3927	3.8e-59	192.0	COG3367@1|root,COG3367@2|Bacteria,1MVEX@1224|Proteobacteria,1RNVG@1236|Gammaproteobacteria,1XT33@135623|Vibrionales	135623|Vibrionales	S	Domain of unknown function (DUF1611_N) Rossmann-like domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF1611,DUF1611_N
k141_3807_1	675816.VIA_001712	6.54e-40	133.0	2CJAG@1|root,32S9M@2|Bacteria,1N4PM@1224|Proteobacteria,1SAGF@1236|Gammaproteobacteria,1XYEJ@135623|Vibrionales	135623|Vibrionales	S	Protein of unknown function (DUF2999)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2999
k141_3807_2	1283284.AZUK01000001_gene66	9.08e-92	275.0	COG0800@1|root,COG0800@2|Bacteria,1MUVJ@1224|Proteobacteria,1RPDF@1236|Gammaproteobacteria,1Y5AQ@135624|Aeromonadales	135624|Aeromonadales	G	2-dehydro-3-deoxyphosphogluconate aldolase 4-hydroxy-2-oxoglutarate aldolase	eda	-	4.1.2.14,4.1.3.42	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	M00008,M00061,M00308,M00631	R00470,R05605	RC00307,RC00308,RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldolase
k141_3807_3	1082705.JIBP01000003_gene2169	6.56e-133	398.0	COG0129@1|root,COG0129@2|Bacteria,1MU3T@1224|Proteobacteria,1RMNA@1236|Gammaproteobacteria	1236|Gammaproteobacteria	EG	Belongs to the IlvD Edd family	edd	GO:0003674,GO:0003824,GO:0004456,GO:0005975,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016052,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0019520,GO:0019521,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044275,GO:0044281,GO:0044282,GO:0046176,GO:0046177,GO:0046395,GO:0071704,GO:0072329,GO:1901575	4.2.1.12	ko:K01690	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00008	R02036	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	iEcolC_1368.EcolC_1781,iJN746.PP_1010,iPC815.YPO2533,iYL1228.KPN_02366	ILVD_EDD
k141_483_1	1116375.VEJY3_08575	1.28e-206	583.0	COG2610@1|root,COG2610@2|Bacteria,1N2VU@1224|Proteobacteria,1RNCQ@1236|Gammaproteobacteria,1XZVF@135623|Vibrionales	135623|Vibrionales	EG	GntP family permease	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_antiporter
k141_4515_1	1121403.AUCV01000057_gene3056	1.47e-87	268.0	2CD97@1|root,33TWU@2|Bacteria,1NVD9@1224|Proteobacteria,42ZM4@68525|delta/epsilon subdivisions,2WUVU@28221|Deltaproteobacteria,2MNAZ@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_4515_2	1121403.AUCV01000057_gene3055	9.39e-54	189.0	COG1196@1|root,COG4942@1|root,COG1196@2|Bacteria,COG4942@2|Bacteria,1R6NJ@1224|Proteobacteria,42WEE@68525|delta/epsilon subdivisions,2WS7W@28221|Deltaproteobacteria,2MM30@213118|Desulfobacterales	28221|Deltaproteobacteria	D	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_1090_1	96561.Dole_2323	9.77e-18	83.6	COG1541@1|root,COG1541@2|Bacteria,1MV1W@1224|Proteobacteria,42NKD@68525|delta/epsilon subdivisions,2WIWV@28221|Deltaproteobacteria,2MIVW@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)	paaK-2	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	iAF987.Gmet_1825	AMP-binding,AMP-binding_C_2
k141_1090_2	1121472.AQWN01000004_gene807	3.76e-34	122.0	COG4747@1|root,COG4747@2|Bacteria,1V7U2@1239|Firmicutes,24JE5@186801|Clostridia,2629K@186807|Peptococcaceae	186801|Clostridia	S	PFAM Amino acid-binding ACT	-	-	-	-	-	-	-	-	-	-	-	-	ACT
k141_3808_1	1042209.HK44_002720	3.86e-18	90.1	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,1YP8C@136843|Pseudomonas fluorescens group	1236|Gammaproteobacteria	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	bdlA	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal,PAS_3,PAS_4,PAS_9
k141_3808_2	319224.Sputcn32_3392	1.72e-13	68.6	COG3118@1|root,COG3118@2|Bacteria,1RHUA@1224|Proteobacteria,1S64W@1236|Gammaproteobacteria,2QBJP@267890|Shewanellaceae	1236|Gammaproteobacteria	O	Belongs to the thioredoxin family	trxC	GO:0003674,GO:0003824,GO:0004791,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008270,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0046872,GO:0046914,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748	1.8.1.8	ko:K03672	-	-	-	-	ko00000,ko01000,ko03110	-	-	iAF1260.b2582,iAPECO1_1312.APECO1_3950,iB21_1397.B21_02440,iBWG_1329.BWG_2346,iE2348C_1286.E2348C_2859,iEC55989_1330.EC55989_2872,iECABU_c1320.ECABU_c28840,iECBD_1354.ECBD_1098,iECB_1328.ECB_02476,iECDH10B_1368.ECDH10B_2750,iECDH1ME8569_1439.ECDH1ME8569_2509,iECD_1391.ECD_02476,iECH74115_1262.ECH74115_3819,iECIAI1_1343.ECIAI1_2700,iECIAI39_1322.ECIAI39_2790,iECO103_1326.ECO103_3161,iECO111_1330.ECO111_3308,iECO26_1355.ECO26_3629,iECOK1_1307.ECOK1_2926,iECP_1309.ECP_2584,iECS88_1305.ECS88_2757,iECSE_1348.ECSE_2871,iECSF_1327.ECSF_2421,iECSP_1301.ECSP_3529,iECW_1372.ECW_m2811,iECs_1301.ECs3448,iEKO11_1354.EKO11_1151,iEcDH1_1363.EcDH1_1086,iEcE24377_1341.EcE24377A_2869,iEcHS_1320.EcHS_A2739,iEcSMS35_1347.EcSMS35_2735,iEcolC_1368.EcolC_1095,iG2583_1286.G2583_3165,iJO1366.b2582,iLF82_1304.LF82_2324,iNRG857_1313.NRG857_12825,iSDY_1059.SDY_2825,iSFV_1184.SFV_2645,iSF_1195.SF2644,iSFxv_1172.SFxv_2901,iSSON_1240.SSON_2708,iS_1188.S2817,iSbBS512_1146.SbBS512_E2954,iUMN146_1321.UM146_03805,iUMNK88_1353.UMNK88_3235,iUTI89_1310.UTI89_C2905,iWFL_1372.ECW_m2811,iY75_1357.Y75_RS13495,iZ_1308.Z3867,ic_1306.c3107	Thioredoxin
k141_3148_1	177437.HRM2_35760	2.05e-35	129.0	COG1286@1|root,COG1286@2|Bacteria,1RJE1@1224|Proteobacteria,42SCW@68525|delta/epsilon subdivisions,2WPNX@28221|Deltaproteobacteria,2MKBI@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Colicin V production protein	-	-	-	ko:K03558	-	-	-	-	ko00000	-	-	-	Colicin_V
k141_3148_2	985665.HPL003_07710	4.68e-60	204.0	COG1694@1|root,COG3956@2|Bacteria,1TPK1@1239|Firmicutes,4HA0A@91061|Bacilli,26QBT@186822|Paenibacillaceae	91061|Bacilli	S	Protein containing tetrapyrrole methyltransferase domain and MazG-like	yabN	GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006213,GO:0006220,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009147,GO:0009149,GO:0009151,GO:0009155,GO:0009164,GO:0009166,GO:0009199,GO:0009200,GO:0009203,GO:0009204,GO:0009208,GO:0009210,GO:0009211,GO:0009213,GO:0009215,GO:0009217,GO:0009218,GO:0009219,GO:0009222,GO:0009223,GO:0009259,GO:0009261,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042454,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046046,GO:0046047,GO:0046051,GO:0046052,GO:0046060,GO:0046061,GO:0046070,GO:0046075,GO:0046076,GO:0046080,GO:0046081,GO:0046131,GO:0046133,GO:0046135,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658	3.6.1.66	ko:K02428,ko:K02499	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000,ko03036	-	-	-	MazG,TP_methylase
k141_3148_5	1121396.KB893101_gene481	1.53e-23	96.7	2BY9J@1|root,32VNR@2|Bacteria,1N0NN@1224|Proteobacteria,42TIE@68525|delta/epsilon subdivisions,2WQUN@28221|Deltaproteobacteria,2MKER@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_3148_6	439235.Dalk_5158	2.66e-60	192.0	COG1051@1|root,COG1051@2|Bacteria,1REBW@1224|Proteobacteria,42T3V@68525|delta/epsilon subdivisions,2WPYF@28221|Deltaproteobacteria,2MKDN@213118|Desulfobacterales	28221|Deltaproteobacteria	F	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
k141_3148_7	1304885.AUEY01000013_gene3099	1.78e-46	162.0	COG0191@1|root,COG0191@2|Bacteria,1NMAK@1224|Proteobacteria,42NPW@68525|delta/epsilon subdivisions,2WIMN@28221|Deltaproteobacteria,2MHU7@213118|Desulfobacterales	28221|Deltaproteobacteria	G	aldolase class-II	-	-	4.1.2.13	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167,M00344,M00345	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	F_bP_aldolase
k141_4516_1	911045.PSE_0014	3.28e-14	71.6	COG5319@1|root,COG5319@2|Bacteria,1MZN2@1224|Proteobacteria,2UBTA@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Protein conserved in bacteria	MA20_39715	-	-	-	-	-	-	-	-	-	-	-	DUF1178
k141_4516_2	933262.AXAM01000057_gene1542	3.31e-29	115.0	COG3103@1|root,COG4991@2|Bacteria,1QWMT@1224|Proteobacteria,42VQW@68525|delta/epsilon subdivisions,2WR75@28221|Deltaproteobacteria,2MK0G@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Bacterial SH3 domain homologues	-	-	-	ko:K07184	-	-	-	-	ko00000	-	-	-	SH3_3
k141_4516_3	933262.AXAM01000018_gene1005	2.08e-59	199.0	COG0029@1|root,COG0029@2|Bacteria,1RBQW@1224|Proteobacteria,43BKD@68525|delta/epsilon subdivisions,2WJNK@28221|Deltaproteobacteria,2MIMB@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Catalyzes the oxidation of L-aspartate to iminoaspartate	nadB	-	1.4.3.16	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	M00115	R00357,R00481	RC00006,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
k141_3520_1	55601.VANGNB10_cI2109	1.88e-142	410.0	COG0598@1|root,COG0598@2|Bacteria,1MW8W@1224|Proteobacteria,1RRTZ@1236|Gammaproteobacteria,1XSI8@135623|Vibrionales	135623|Vibrionales	P	COG0598 Mg2 and Co2 transporters	-	-	-	ko:K16074	-	-	-	-	ko00000,ko02000	1.A.35.4	-	-	CorA
k141_3520_2	1232683.ADIMK_0853	5.67e-308	881.0	COG2206@1|root,COG3437@1|root,COG2206@2|Bacteria,COG3437@2|Bacteria,1MV37@1224|Proteobacteria,1RM9C@1236|Gammaproteobacteria,465R9@72275|Alteromonadaceae	1236|Gammaproteobacteria	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_3,HD_5,dCache_1
k141_3520_3	1348635.BBJY01000008_gene1728	7.24e-177	500.0	COG1816@1|root,COG1816@2|Bacteria,1MWBV@1224|Proteobacteria,1RNVI@1236|Gammaproteobacteria,1XU77@135623|Vibrionales	135623|Vibrionales	F	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism	-	-	3.5.4.2	ko:K21053	ko00230,ko01100,map00230,map01100	-	R01244	RC00477	ko00000,ko00001,ko01000	-	-	-	A_deaminase
k141_3520_4	1348635.BBJY01000002_gene3505	4.98e-202	564.0	COG2171@1|root,COG2171@2|Bacteria,1MYKK@1224|Proteobacteria,1RM8X@1236|Gammaproteobacteria,1XT0E@135623|Vibrionales	135623|Vibrionales	H	Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA	dapD	GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008666,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0016748,GO:0016749,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.3.1.117	ko:K00674	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R04365	RC00004,RC01136	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep_2,THDPS_M,THDPS_N
k141_3520_5	1238450.VIBNISOn1_490004	2.05e-38	131.0	COG3141@1|root,COG3141@2|Bacteria,1N6RQ@1224|Proteobacteria,1SCDB@1236|Gammaproteobacteria,1XXX8@135623|Vibrionales	135623|Vibrionales	S	protein conserved in bacteria	-	-	-	ko:K09918	-	-	-	-	ko00000	-	-	-	YebG
k141_3520_6	1348635.BBJY01000002_gene3503	6.22e-157	446.0	COG0583@1|root,COG0583@2|Bacteria,1MWVU@1224|Proteobacteria,1RPT8@1236|Gammaproteobacteria,1XTXE@135623|Vibrionales	135623|Vibrionales	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
k141_2769_1	1348635.BBJY01000003_gene3736	0.0	1093.0	COG2206@1|root,COG3437@1|root,COG2206@2|Bacteria,COG3437@2|Bacteria,1MV37@1224|Proteobacteria,1RM9C@1236|Gammaproteobacteria,1XSHM@135623|Vibrionales	135623|Vibrionales	KT	COG0840 Methyl-accepting chemotaxis protein	-	-	-	-	-	-	-	-	-	-	-	-	HD,HD_5,dCache_1
k141_2769_2	1238450.VIBNISOn1_230042	1.81e-50	174.0	COG0364@1|root,COG0364@2|Bacteria,1MUN0@1224|Proteobacteria,1RN76@1236|Gammaproteobacteria,1XSC7@135623|Vibrionales	135623|Vibrionales	G	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone	zwf	-	1.1.1.363,1.1.1.49	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	M00004,M00006,M00008	R00835,R02736,R10907	RC00001,RC00066	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	G6PD_C,G6PD_N
k141_484_1	1208321.D104_03415	1.32e-31	118.0	COG3769@1|root,COG3769@2|Bacteria,1NFV5@1224|Proteobacteria,1RR9R@1236|Gammaproteobacteria,1XJXF@135619|Oceanospirillales	135619|Oceanospirillales	S	Mannosyl-3-phosphoglycerate phosphatase	-	-	3.1.3.70	ko:K07026	ko00051,map00051	-	R05790	RC00017	ko00000,ko00001,ko01000	-	-	-	Hydrolase_3,S6PP
k141_484_2	400668.Mmwyl1_1772	1.68e-261	720.0	COG1215@1|root,COG1215@2|Bacteria,1MWH9@1224|Proteobacteria,1RPTN@1236|Gammaproteobacteria,1XHKE@135619|Oceanospirillales	135619|Oceanospirillales	M	Glycosyl transferase	-	-	2.4.1.266	ko:K13693	-	-	-	-	ko00000,ko01000,ko01003	-	GT81	-	-
k141_484_3	717774.Marme_2483	0.0	995.0	COG0366@1|root,COG0366@2|Bacteria,1MVKX@1224|Proteobacteria,1RMXP@1236|Gammaproteobacteria,1XHYU@135619|Oceanospirillales	135619|Oceanospirillales	G	Alpha amylase, catalytic domain	-	-	2.4.1.7	ko:K00690	ko00500,map00500	-	R00803	RC00028	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,Malt_amylase_C
k141_1091_2	1278307.KB906984_gene4375	4.49e-152	452.0	COG0457@1|root,COG0457@2|Bacteria,1R8N2@1224|Proteobacteria,1S19V@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF2971)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2971
k141_1091_3	983545.Glaag_4548	2.62e-110	325.0	COG2801@1|root,COG2801@2|Bacteria,1MVXQ@1224|Proteobacteria,1RPEW@1236|Gammaproteobacteria,467PH@72275|Alteromonadaceae	1236|Gammaproteobacteria	L	COG2801 Transposase and inactivated derivatives	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve
k141_1091_4	1448139.AI20_13790	5.86e-51	162.0	COG2963@1|root,COG2963@2|Bacteria,1N04F@1224|Proteobacteria,1S9BV@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Transposase	-	-	-	ko:K07483	-	-	-	-	ko00000	-	-	-	HTH_Tnp_1
k141_2430_1	1219080.VEZ01S_26_00390	2.63e-30	122.0	COG1061@1|root,COG1061@2|Bacteria,1QCQA@1224|Proteobacteria,1TJTE@1236|Gammaproteobacteria,1Y1NI@135623|Vibrionales	135623|Vibrionales	KL	DEAD-like helicases superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,ResIII
k141_2430_2	377629.TERTU_0792	0.0	1154.0	COG0433@1|root,COG0433@2|Bacteria,1MUSH@1224|Proteobacteria,1RXZ7@1236|Gammaproteobacteria,2PPGI@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	S	AAA-like domain	-	-	-	ko:K06915	-	-	-	-	ko00000	-	-	-	DUF853,DUF87
k141_2430_3	1051646.VITU9109_00600	2.31e-14	71.2	arCOG14100@1|root,2Z924@2|Bacteria,1R4ME@1224|Proteobacteria,1RZ4G@1236|Gammaproteobacteria,1XYPP@135623|Vibrionales	135623|Vibrionales	S	SIR2-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SIR2_2
k141_3521_1	118166.JH976538_gene5057	1.7e-119	374.0	COG4191@1|root,COG4191@2|Bacteria,1G1PE@1117|Cyanobacteria,1H8US@1150|Oscillatoriales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,PAS_4,PAS_8,Response_reg
k141_2770_1	1214065.BAGV01000019_gene2616	1.77e-39	141.0	COG0515@1|root,COG0515@2|Bacteria,1RI1C@1224|Proteobacteria,1SBJW@1236|Gammaproteobacteria	1236|Gammaproteobacteria	KLT	PhoP regulatory network protein YrbL	-	-	-	-	-	-	-	-	-	-	-	-	YrbL-PhoP_reg
k141_3522_1	177439.DP0499	1.37e-56	189.0	COG2145@1|root,COG2145@2|Bacteria,1MVES@1224|Proteobacteria,42PAR@68525|delta/epsilon subdivisions,2WMWU@28221|Deltaproteobacteria,2MJHN@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)	thiM	-	2.7.1.50	ko:K00878	ko00730,ko01100,map00730,map01100	M00127	R04448	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HK
k141_4519_1	1120998.AUFC01000007_gene1137	8.71e-59	200.0	COG0534@1|root,COG0534@2|Bacteria,1TPPJ@1239|Firmicutes,25AZE@186801|Clostridia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	MatE
k141_4520_1	877418.ATWV01000004_gene1866	3.45e-40	152.0	COG1629@1|root,COG4771@2|Bacteria,2J6M8@203691|Spirochaetes	203691|Spirochaetes	P	TonB-dependent Receptor Plug Domain	-	-	-	-	-	-	-	-	-	-	-	-	Plug
k141_3152_1	338966.Ppro_2089	2.43e-89	301.0	COG0784@1|root,COG2202@1|root,COG4936@1|root,COG5002@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG4936@2|Bacteria,COG5002@2|Bacteria,1NC9X@1224|Proteobacteria,43BSJ@68525|delta/epsilon subdivisions,2X73B@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_9,Response_reg
k141_2431_1	1449050.JNLE01000003_gene2934	1.56e-58	200.0	COG1162@1|root,COG1162@2|Bacteria,1TP8Q@1239|Firmicutes,249F8@186801|Clostridia,36FBR@31979|Clostridiaceae	186801|Clostridia	S	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit	rsgA	-	3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100	-	R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009	-	-	-	RsgA_GTPase
k141_3153_1	869210.Marky_0181	1.04e-13	77.0	COG1353@1|root,COG1353@2|Bacteria,1WJHX@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	CRISPR-associated protein, Csm1 family	-	-	-	ko:K07016	-	-	-	-	ko00000,ko02048	-	-	-	HD
k141_3809_3	345073.VC395_2572	2.53e-47	155.0	COG0736@1|root,COG0736@2|Bacteria,1MZBF@1224|Proteobacteria,1S98P@1236|Gammaproteobacteria,1XXAM@135623|Vibrionales	135623|Vibrionales	I	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein	acpS	GO:0003674,GO:0003824,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008897,GO:0009058,GO:0016740,GO:0016772,GO:0016780,GO:0044238,GO:0071704,GO:1901576	2.7.8.7	ko:K00997	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	-	ACPS
k141_3809_4	55601.VANGNB10_cI2216	0.0	1304.0	COG0642@1|root,COG0745@1|root,COG2198@1|root,COG0745@2|Bacteria,COG2198@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,1SKTW@1236|Gammaproteobacteria,1XV4F@135623|Vibrionales	135623|Vibrionales	T	Histidine kinase	barA	-	2.7.13.3	ko:K07678	ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111	M00475	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF2222,HATPase_c,HisKA,Hpt,Response_reg
k141_3809_5	675815.VOA_002763	2.02e-30	118.0	COG2265@1|root,COG2265@2|Bacteria,1MV3A@1224|Proteobacteria,1RN1D@1236|Gammaproteobacteria,1XUN9@135623|Vibrionales	135623|Vibrionales	J	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA	rlmD	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TRAM,tRNA_U5-meth_tr
k141_1092_1	498211.CJA_2520	3.07e-237	757.0	COG1022@1|root,COG5184@1|root,COG5276@1|root,COG1022@2|Bacteria,COG5184@2|Bacteria,COG5276@2|Bacteria,1PG4J@1224|Proteobacteria,1RWXR@1236|Gammaproteobacteria,1FIEH@10|Cellvibrio	1236|Gammaproteobacteria	DZ	Regulator of chromosome condensation (RCC1) repeat	-	-	-	-	-	-	-	-	-	-	-	-	RCC1
k141_1093_1	1499683.CCFF01000017_gene2789	1.56e-41	150.0	COG0438@1|root,COG0438@2|Bacteria,1V5CR@1239|Firmicutes,24MFQ@186801|Clostridia,36Q97@31979|Clostridiaceae	186801|Clostridia	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
k141_3810_1	1123326.JFBL01000025_gene14	3.41e-32	115.0	COG2350@1|root,COG2350@2|Bacteria,1N8AZ@1224|Proteobacteria,42V5N@68525|delta/epsilon subdivisions,2YQFM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
k141_3810_2	448385.sce6368	1.47e-32	125.0	COG1506@1|root,COG1506@2|Bacteria,1Q3VB@1224|Proteobacteria,43439@68525|delta/epsilon subdivisions,2X511@28221|Deltaproteobacteria,2YZYQ@29|Myxococcales	28221|Deltaproteobacteria	E	Prolyl oligopeptidase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S9
k141_4521_1	55601.VANGNB10_cII1001	2.12e-115	351.0	COG2274@1|root,COG2274@2|Bacteria,1R2T0@1224|Proteobacteria,1SBE1@1236|Gammaproteobacteria,1XTY1@135623|Vibrionales	135623|Vibrionales	V	COG2274 ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain	lapB	-	-	ko:K12541	ko02010,map02010	M00330	-	-	ko00000,ko00001,ko00002,ko02000,ko02044	3.A.1.109.3,3.A.1.109.4	-	-	ABC_membrane,ABC_tran,Peptidase_C39
k141_4521_2	1219065.VPR01S_12_01270	1.7e-272	764.0	COG2199@1|root,COG2200@1|root,COG2199@2|Bacteria,COG2200@2|Bacteria,1MUQV@1224|Proteobacteria,1RN0Q@1236|Gammaproteobacteria,1XU7X@135623|Vibrionales	135623|Vibrionales	T	COG2199 FOG GGDEF domain	VVA1653	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,HAMP,LapD_MoxY_N
k141_3812_1	289376.THEYE_A0277	6.99e-98	293.0	COG0413@1|root,COG0413@2|Bacteria,3J0GX@40117|Nitrospirae	40117|Nitrospirae	H	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate	panB	-	2.1.2.11	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R01226	RC00022,RC00200	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_transf
k141_4522_1	381666.H16_A1469	5.52e-56	194.0	COG0154@1|root,COG0154@2|Bacteria,1MU51@1224|Proteobacteria,2VIXK@28216|Betaproteobacteria,1KH4S@119060|Burkholderiaceae	28216|Betaproteobacteria	J	Belongs to the amidase family	-	-	3.5.1.4,6.3.5.6,6.3.5.7	ko:K01426,ko:K02433	ko00330,ko00360,ko00380,ko00627,ko00643,ko00970,ko01100,ko01120,map00330,map00360,map00380,map00627,map00643,map00970,map01100,map01120	-	R02540,R03096,R03180,R03905,R03909,R04212,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
k141_1094_1	1265505.ATUG01000001_gene4405	1.47e-170	492.0	COG2855@1|root,COG2855@2|Bacteria,1MVPE@1224|Proteobacteria,42NT6@68525|delta/epsilon subdivisions,2WJ9R@28221|Deltaproteobacteria,2MMP4@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Conserved hypothetical protein 698	-	-	-	-	-	-	-	-	-	-	-	-	Cons_hypoth698
k141_1094_3	290512.Paes_1873	3.75e-54	177.0	COG1432@1|root,COG1432@2|Bacteria,1FECY@1090|Chlorobi	1090|Chlorobi	NU	OST-HTH/LOTUS domain	-	-	-	-	-	-	-	-	-	-	-	-	NYN,OST-HTH
k141_1793_1	1219065.VPR01S_27_00230	5.95e-209	591.0	COG0661@1|root,COG0661@2|Bacteria,1MU1Z@1224|Proteobacteria,1RNQM@1236|Gammaproteobacteria,1XSB2@135623|Vibrionales	135623|Vibrionales	H	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis	ubiB	GO:0003674,GO:0003824,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663	-	ko:K03688	-	-	-	-	ko00000	-	-	-	ABC1
k141_1793_2	1118153.MOY_09595	1.59e-15	71.6	COG1826@1|root,COG1826@2|Bacteria,1N6S4@1224|Proteobacteria,1SCC7@1236|Gammaproteobacteria,1XM7C@135619|Oceanospirillales	135619|Oceanospirillales	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system	tatA	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
k141_1793_3	314285.KT71_03930	9.92e-10	60.1	COG1826@1|root,COG1826@2|Bacteria,1PJQQ@1224|Proteobacteria,1SWZC@1236|Gammaproteobacteria,1JARM@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation	tatB	-	-	-	-	-	-	-	-	-	-	-	MttA_Hcf106
k141_1793_4	1517681.HW45_18665	8.39e-133	382.0	COG0805@1|root,COG0805@2|Bacteria,1MVAY@1224|Proteobacteria,1RPRN@1236|Gammaproteobacteria,1XTQ1@135623|Vibrionales	135623|Vibrionales	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides	tatC	-	-	ko:K03118	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	TatC
k141_1120_1	1265505.ATUG01000002_gene1391	2.22e-05	52.8	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42N0F@68525|delta/epsilon subdivisions,2WJAE@28221|Deltaproteobacteria,2MIUP@213118|Desulfobacterales	28221|Deltaproteobacteria	NT	PFAM chemotaxis sensory transducer	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CZB,HAMP,MCPsignal
k141_2528_31	243277.VC_2721	3.19e-99	292.0	COG0494@1|root,COG0494@2|Bacteria,1RCX7@1224|Proteobacteria,1S3ZE@1236|Gammaproteobacteria,1XSE9@135623|Vibrionales	135623|Vibrionales	L	COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes	nudE	-	-	ko:K08312	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
k141_2528_32	1238450.VIBNISOn1_1440018	4.48e-120	345.0	COG0316@1|root,COG0694@1|root,COG0316@2|Bacteria,COG0694@2|Bacteria,1MU8Y@1224|Proteobacteria,1RN7J@1236|Gammaproteobacteria,1XSGB@135623|Vibrionales	135623|Vibrionales	C	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins	nfuA	-	-	ko:K07400	-	-	-	-	ko00000	-	-	-	Fe-S_biosyn,NifU
k141_2528_33	1219065.VPR01S_04_02790	7.68e-66	208.0	COG1040@1|root,COG1040@2|Bacteria,1RHAV@1224|Proteobacteria,1S64Q@1236|Gammaproteobacteria,1XT5I@135623|Vibrionales	135623|Vibrionales	S	Phosphoribosyl transferase domain	gntX	-	-	-	-	-	-	-	-	-	-	-	Pribosyltran
k141_2528_34	1348635.BBJY01000009_gene1476	1.25e-106	316.0	COG0596@1|root,COG0596@2|Bacteria,1QUBR@1224|Proteobacteria,1RSF9@1236|Gammaproteobacteria,1XSHE@135623|Vibrionales	135623|Vibrionales	S	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters	bioH	GO:0003674,GO:0003824,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016787,GO:0017144,GO:0018130,GO:0019752,GO:0032787,GO:0034641,GO:0042364,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	3.1.1.85	ko:K02170	ko00780,ko01100,map00780,map01100	M00572	R09725	RC00460,RC00461	ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_1
k141_2528_35	243277.VC_2717	5.27e-66	205.0	2APKV@1|root,31EQ4@2|Bacteria,1QJN4@1224|Proteobacteria,1THNR@1236|Gammaproteobacteria,1XWYE@135623|Vibrionales	135623|Vibrionales	-	-	VV10861	-	-	-	-	-	-	-	-	-	-	-	-
k141_2528_37	1056512.D515_01665	4.23e-86	257.0	COG0782@1|root,COG0782@2|Bacteria,1RAP0@1224|Proteobacteria,1S40Q@1236|Gammaproteobacteria,1XV4E@135623|Vibrionales	135623|Vibrionales	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length	greB	-	-	ko:K04760	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
k141_2528_38	579405.Dd703_0735	6.84e-168	484.0	COG1448@1|root,COG1448@2|Bacteria,1MUT0@1224|Proteobacteria,1RN02@1236|Gammaproteobacteria,2JDU7@204037|Dickeya	1236|Gammaproteobacteria	E	PFAM aminotransferase class I and II	tyrB	-	2.6.1.57	ko:K00832	ko00270,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230	M00024,M00025,M00034,M00040	R00694,R00734,R01731,R07396,R10845	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	iJN746.PP_3590	Aminotran_1_2
k141_2528_40	701176.VIBRN418_01161	1.34e-181	520.0	COG0642@1|root,COG2205@2|Bacteria,1MUAK@1224|Proteobacteria,1RPP2@1236|Gammaproteobacteria,1XSMP@135623|Vibrionales	135623|Vibrionales	T	Osmolarity sensor protein	envZ	-	2.7.13.3	ko:K07638	ko02020,ko02026,map02020,map02026	M00445,M00742,M00743	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
k141_2528_41	55601.VANGNB10_cI2351c	5e-66	201.0	COG0051@1|root,COG0051@2|Bacteria,1RGWF@1224|Proteobacteria,1S3QX@1236|Gammaproteobacteria,1XXAA@135623|Vibrionales	135623|Vibrionales	J	Involved in the binding of tRNA to the ribosomes	rpsJ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02946	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S10
k141_2528_42	675813.VIB_000538	6.62e-138	391.0	COG0087@1|root,COG0087@2|Bacteria,1MUST@1224|Proteobacteria,1RMK9@1236|Gammaproteobacteria,1XSH7@135623|Vibrionales	135623|Vibrionales	J	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit	rplC	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02906	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L3
k141_2528_43	55601.VANGNB10_cI2349c	1.1e-127	364.0	COG0088@1|root,COG0088@2|Bacteria,1MXPF@1224|Proteobacteria,1RNNK@1236|Gammaproteobacteria,1XSUF@135623|Vibrionales	135623|Vibrionales	J	Forms part of the polypeptide exit tunnel	rplD	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02926	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L4
k141_2528_44	1188252.AJYK01000108_gene2344	6.69e-56	175.0	COG0089@1|root,COG0089@2|Bacteria,1MZXX@1224|Proteobacteria,1S8VX@1236|Gammaproteobacteria,1XXSC@135623|Vibrionales	135623|Vibrionales	J	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome	rplW	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02892	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L23
k141_2528_45	945543.VIBR0546_15012	1.06e-189	527.0	COG0090@1|root,COG0090@2|Bacteria,1MVTD@1224|Proteobacteria,1RMGR@1236|Gammaproteobacteria,1XU36@135623|Vibrionales	135623|Vibrionales	J	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity	rplB	GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02886	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L2,Ribosomal_L2_C
k141_2528_46	998088.B565_0187	3.33e-59	182.0	COG0185@1|root,COG0185@2|Bacteria,1RGYX@1224|Proteobacteria,1S5VT@1236|Gammaproteobacteria,1Y4JB@135624|Aeromonadales	135624|Aeromonadales	J	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA	rpsS	-	-	ko:K02965	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S19
k141_2528_47	55601.VANGNB10_cI2345c	6.11e-68	206.0	COG0091@1|root,COG0091@2|Bacteria,1RH0W@1224|Proteobacteria,1S5XT@1236|Gammaproteobacteria,1XX9S@135623|Vibrionales	135623|Vibrionales	J	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome	rplV	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02890	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L22
k141_324_2	398512.JQKC01000001_gene2282	2.39e-50	172.0	COG0609@1|root,COG0609@2|Bacteria,1TPX6@1239|Firmicutes,248IS@186801|Clostridia,3WNNT@541000|Ruminococcaceae	186801|Clostridia	P	FecCD transport family	-	-	-	ko:K02015	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	FecCD
k141_4657_1	1121396.KB893062_gene2778	2.05e-176	501.0	COG1690@1|root,COG1690@2|Bacteria,1MUHA@1224|Proteobacteria,42MZN@68525|delta/epsilon subdivisions,2WJGK@28221|Deltaproteobacteria,2MHPF@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Belongs to the RtcB family	rtcB	-	6.5.1.3	ko:K14415	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RtcB
k141_2290_1	1121441.AUCX01000009_gene2463	1e-19	95.5	COG1226@1|root,COG1226@2|Bacteria,1QDMQ@1224|Proteobacteria,435QP@68525|delta/epsilon subdivisions,2X04Z@28221|Deltaproteobacteria,2MAJ0@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	Ion transport protein	-	-	-	-	-	-	-	-	-	-	-	-	Ion_trans_2,TrkA_N
k141_3656_1	223926.28807066	4.07e-30	111.0	COG1495@1|root,COG1495@2|Bacteria,1RIJE@1224|Proteobacteria,1S6WD@1236|Gammaproteobacteria,1XV2K@135623|Vibrionales	135623|Vibrionales	C	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein	dsbB	GO:0006457,GO:0008150,GO:0009987	-	ko:K03611	-	-	-	-	ko00000,ko03110	5.A.2.1	-	-	DsbB
k141_3656_2	1219065.VPR01S_03_00800	3.97e-231	650.0	COG3067@1|root,COG3067@2|Bacteria,1MV0F@1224|Proteobacteria,1RPE3@1236|Gammaproteobacteria,1XT42@135623|Vibrionales	135623|Vibrionales	P	) H( ) antiporter that extrudes sodium in exchange for external protons	nhaB	GO:0003674,GO:0005215,GO:0005451,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008150,GO:0008324,GO:0015075,GO:0015077,GO:0015078,GO:0015081,GO:0015291,GO:0015297,GO:0015298,GO:0015299,GO:0015318,GO:0015385,GO:0015491,GO:0015672,GO:0016020,GO:0022804,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0035725,GO:0044464,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:0099516,GO:1902600	-	ko:K03314	-	-	-	-	ko00000,ko02000	2.A.34.1	-	-	NhaB
k141_2291_1	1121289.JHVL01000012_gene1726	2.7e-126	371.0	COG0427@1|root,COG0427@2|Bacteria,1TPHC@1239|Firmicutes,247V0@186801|Clostridia,36FHR@31979|Clostridiaceae	186801|Clostridia	C	acetyl-CoA hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	AcetylCoA_hyd_C,AcetylCoA_hydro
k141_4658_1	1348635.BBJY01000029_gene2053	7.19e-44	145.0	COG3448@1|root,COG3448@2|Bacteria,1MXJG@1224|Proteobacteria,1RYFC@1236|Gammaproteobacteria,1XXB9@135623|Vibrionales	135623|Vibrionales	T	HPP family	-	-	-	-	-	-	-	-	-	-	-	-	HPP
k141_4658_2	1348635.BBJY01000029_gene2052	4.64e-119	342.0	COG1309@1|root,COG1309@2|Bacteria,1R67Z@1224|Proteobacteria,1S63V@1236|Gammaproteobacteria,1Y2E4@135623|Vibrionales	135623|Vibrionales	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
k141_2530_1	298386.PBPRB1351	4.94e-117	343.0	COG0583@1|root,COG0583@2|Bacteria,1R4QT@1224|Proteobacteria,1RR79@1236|Gammaproteobacteria,1XT7K@135623|Vibrionales	1236|Gammaproteobacteria	K	Bacterial regulatory helix-turn-helix protein, lysR family	yjiE	GO:0000976,GO:0001017,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0005515,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031326,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0042802,GO:0043170,GO:0043565,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1903506,GO:1990837,GO:2000112,GO:2001141	-	ko:K21645	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,LysR_substrate
k141_1278_1	1219076.N646_2333	3.3e-161	455.0	COG1218@1|root,COG1218@2|Bacteria,1N0GY@1224|Proteobacteria,1RP5A@1236|Gammaproteobacteria,1XUIT@135623|Vibrionales	135623|Vibrionales	P	COG1218 3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase	cysQ	-	3.1.3.7	ko:K01082	ko00920,ko01100,ko01120,ko01130,map00920,map01100,map01120,map01130	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03016	-	-	-	Inositol_P
k141_1278_2	575788.VS_0147	4.94e-101	296.0	COG0494@1|root,COG0494@2|Bacteria,1RCX7@1224|Proteobacteria,1S3ZE@1236|Gammaproteobacteria,1XSE9@135623|Vibrionales	135623|Vibrionales	L	COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes	nudE	-	-	ko:K08312	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
k141_1278_3	674977.VMC_13990	3.84e-117	337.0	COG0316@1|root,COG0694@1|root,COG0316@2|Bacteria,COG0694@2|Bacteria,1MU8Y@1224|Proteobacteria,1RN7J@1236|Gammaproteobacteria,1XSGB@135623|Vibrionales	135623|Vibrionales	C	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins	nfuA	-	-	ko:K07400	-	-	-	-	ko00000	-	-	-	Fe-S_biosyn,NifU
k141_1278_4	672.VV93_v1c02100	9.12e-67	213.0	COG1040@1|root,COG1040@2|Bacteria,1RHAV@1224|Proteobacteria,1S64Q@1236|Gammaproteobacteria,1XT5I@135623|Vibrionales	135623|Vibrionales	S	Phosphoribosyl transferase domain	gntX	-	-	-	-	-	-	-	-	-	-	-	Pribosyltran
k141_1278_5	243277.VC_2718	6.3e-121	352.0	COG0596@1|root,COG0596@2|Bacteria,1QUBR@1224|Proteobacteria,1RSF9@1236|Gammaproteobacteria,1XSHE@135623|Vibrionales	135623|Vibrionales	S	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters	bioH	GO:0003674,GO:0003824,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016787,GO:0017144,GO:0018130,GO:0019752,GO:0032787,GO:0034641,GO:0042364,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	3.1.1.85	ko:K02170	ko00780,ko01100,map00780,map01100	M00572	R09725	RC00460,RC00461	ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_1
k141_1278_6	55601.VANGNB10_cI0171	4.01e-70	215.0	2APKV@1|root,31EQ4@2|Bacteria,1QJN4@1224|Proteobacteria,1THNR@1236|Gammaproteobacteria,1XWYE@135623|Vibrionales	135623|Vibrionales	-	-	VV10861	-	-	-	-	-	-	-	-	-	-	-	-
k141_1278_7	674977.VMC_14030	0.0	1247.0	COG2183@1|root,COG2183@2|Bacteria,1MUA7@1224|Proteobacteria,1RMNH@1236|Gammaproteobacteria,1XTBQ@135623|Vibrionales	135623|Vibrionales	K	accessory protein	yhgF	-	-	ko:K06959	-	-	-	-	ko00000	-	-	-	HHH_3,S1,Tex_N,Tex_YqgF
k141_1278_9	82996.sch_23835	1.66e-206	583.0	COG1113@1|root,COG1113@2|Bacteria,1MUPS@1224|Proteobacteria,1RNK0@1236|Gammaproteobacteria,404IA@613|Serratia	1236|Gammaproteobacteria	E	Amino acid permease	aroP	-	-	ko:K11734	-	-	-	-	ko00000,ko02000	2.A.3.1.3	-	-	AA_permease
k141_1278_10	561231.Pecwa_3640	9.04e-26	100.0	COG1522@1|root,COG1522@2|Bacteria,1QW36@1224|Proteobacteria,1S2P5@1236|Gammaproteobacteria,1MR5T@122277|Pectobacterium	1236|Gammaproteobacteria	K	helix_turn_helix ASNC type	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg,HTH_24,HTH_AsnC-type
k141_1278_11	1116375.VEJY3_23026	2.59e-107	313.0	COG1284@1|root,COG1284@2|Bacteria,1RDIV@1224|Proteobacteria,1RSIN@1236|Gammaproteobacteria,1XT16@135623|Vibrionales	1236|Gammaproteobacteria	S	Uncharacterised 5xTM membrane BCR, YitT family COG1284	-	-	-	-	-	-	-	-	-	-	-	-	YitT_membrane
k141_1278_12	1116375.VEJY3_23021	9.61e-232	644.0	COG1448@1|root,COG1448@2|Bacteria,1MUT0@1224|Proteobacteria,1RN02@1236|Gammaproteobacteria,1Y01E@135623|Vibrionales	135623|Vibrionales	E	Aminotransferase class I and II	-	-	2.6.1.57	ko:K00832	ko00270,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230	M00024,M00025,M00034,M00040	R00694,R00734,R01731,R07396,R10845	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
k141_1278_13	675815.VOA_003551	2.43e-153	432.0	COG0745@1|root,COG0745@2|Bacteria,1MY3D@1224|Proteobacteria,1RPKN@1236|Gammaproteobacteria,1XUWU@135623|Vibrionales	135623|Vibrionales	K	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	ompR	-	-	ko:K07659	ko02020,ko02026,map02020,map02026	M00445,M00742,M00743	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
k141_1278_14	945543.VIBR0546_13427	1.78e-222	624.0	COG0642@1|root,COG2205@2|Bacteria,1MUAK@1224|Proteobacteria,1RPP2@1236|Gammaproteobacteria,1XSMP@135623|Vibrionales	135623|Vibrionales	T	Osmolarity sensor protein	envZ	-	2.7.13.3	ko:K07638	ko02020,ko02026,map02020,map02026	M00445,M00742,M00743	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
k141_1278_15	1348635.BBJY01000006_gene332	5.77e-61	191.0	COG0589@1|root,COG0589@2|Bacteria,1MV6Y@1224|Proteobacteria,1RQQ7@1236|Gammaproteobacteria,1XX6F@135623|Vibrionales	135623|Vibrionales	T	COG0589 Universal stress protein UspA and related nucleotide-binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	Usp
k141_2292_1	1167006.UWK_01290	9.76e-12	69.7	COG0683@1|root,COG0683@2|Bacteria,1MWR8@1224|Proteobacteria,42NI3@68525|delta/epsilon subdivisions,2WJ6P@28221|Deltaproteobacteria,2MHUH@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Periplasmic binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_6
k141_1956_1	1348635.BBJY01000006_gene494	1.35e-138	397.0	COG4213@1|root,COG4213@2|Bacteria,1MX63@1224|Proteobacteria,1RRJ3@1236|Gammaproteobacteria,1XY35@135623|Vibrionales	135623|Vibrionales	G	Periplasmic binding protein domain	-	-	-	ko:K10543	ko02010,map02010	M00215	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.4	-	-	Peripla_BP_4
k141_1956_2	1348635.BBJY01000006_gene495	1.15e-315	865.0	COG1129@1|root,COG1129@2|Bacteria,1MU22@1224|Proteobacteria,1RMCH@1236|Gammaproteobacteria,1XUXI@135623|Vibrionales	135623|Vibrionales	P	ABC transporter	-	-	3.6.3.17	ko:K10545	ko02010,map02010	M00215	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2.4	-	-	ABC_tran
k141_1956_3	1348635.BBJY01000006_gene496	1.12e-238	661.0	COG4214@1|root,COG4214@2|Bacteria,1MXXS@1224|Proteobacteria,1RNWF@1236|Gammaproteobacteria,1XV7A@135623|Vibrionales	135623|Vibrionales	G	Branched-chain amino acid transport system / permease component	-	-	-	ko:K10544	ko02010,map02010	M00215	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.4	-	-	BPD_transp_2
k141_1956_4	983545.Glaag_3717	1.67e-10	60.8	COG2115@1|root,COG2115@2|Bacteria,1MXS2@1224|Proteobacteria,1RN5Y@1236|Gammaproteobacteria,465DN@72275|Alteromonadaceae	1236|Gammaproteobacteria	G	Belongs to the xylose isomerase family	xylA	GO:0003674,GO:0003824,GO:0005975,GO:0005996,GO:0008150,GO:0008152,GO:0009045,GO:0009056,GO:0016052,GO:0016853,GO:0016860,GO:0016861,GO:0019321,GO:0019323,GO:0042732,GO:0042843,GO:0044238,GO:0044281,GO:0044282,GO:0046365,GO:0071704,GO:1901575	5.3.1.5	ko:K01805	ko00040,ko00051,ko01100,map00040,map00051,map01100	-	R00878,R01432	RC00376,RC00516	ko00000,ko00001,ko01000	-	-	-	-
k141_4967_47	324057.Pjdr2_5781	3.11e-09	70.1	COG3103@1|root,COG3103@2|Bacteria,1UJG3@1239|Firmicutes	1239|Firmicutes	T	S-layer homology domain	-	-	-	-	-	-	-	-	-	-	-	-	SLH
k141_4967_48	1209989.TepiRe1_2680	1.39e-165	485.0	COG2755@1|root,COG2755@2|Bacteria,1TS9T@1239|Firmicutes,24961@186801|Clostridia	186801|Clostridia	E	S-layer homology domain	-	-	-	-	-	-	-	-	-	-	-	-	SLH
k141_4967_49	1209989.TepiRe1_2681	1.9e-131	412.0	2DBEI@1|root,2Z8SE@2|Bacteria,1UYCK@1239|Firmicutes,247WI@186801|Clostridia,42J8P@68295|Thermoanaerobacterales	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	SLH
k141_1988_1	469617.FUAG_02829	5.4e-62	198.0	COG1139@1|root,COG1139@2|Bacteria,37AJW@32066|Fusobacteria	32066|Fusobacteria	C	Pfam:DUF162	-	-	-	-	-	-	-	-	-	-	-	-	LUD_dom
k141_3263_1	278963.ATWD01000001_gene2861	1.19e-165	480.0	COG3344@1|root,COG3344@2|Bacteria,3Y46K@57723|Acidobacteria,2JJPA@204432|Acidobacteriia	204432|Acidobacteriia	L	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	2.7.7.49	ko:K00986	-	-	-	-	ko00000,ko01000	-	-	-	GIIM,RVT_1,RVT_N
k141_4298_1	634177.GLX_29450	8.89e-132	398.0	COG0620@1|root,COG0620@2|Bacteria,1MUI9@1224|Proteobacteria,2TU9X@28211|Alphaproteobacteria,2JR0M@204441|Rhodospirillales	204441|Rhodospirillales	E	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation	metE	-	2.1.1.14	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	M00017	R04405,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	Meth_synt_1,Meth_synt_2
k141_4298_2	1232437.KL661967_gene5051	2.69e-225	634.0	COG0107@1|root,COG0118@1|root,COG0107@2|Bacteria,COG0118@2|Bacteria,1MUS0@1224|Proteobacteria,42M44@68525|delta/epsilon subdivisions,2WJFW@28221|Deltaproteobacteria,2MIFH@213118|Desulfobacterales	28221|Deltaproteobacteria	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit	hisF	-	-	ko:K01663,ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase,His_biosynth
k141_2872_1	1121396.KB893085_gene344	3.66e-103	344.0	COG1020@1|root,COG3321@1|root,COG1020@2|Bacteria,COG3321@2|Bacteria,1QK4F@1224|Proteobacteria,42Z5Y@68525|delta/epsilon subdivisions,2X8JI@28221|Deltaproteobacteria,2MMZD@213118|Desulfobacterales	28221|Deltaproteobacteria	Q	Condensation domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_1,Condensation,KAsynt_C_assoc,KR,Ketoacyl-synt_C,PP-binding,PS-DH,ketoacyl-synt
k141_2559_1	1131553.JIBI01000052_gene22	2.52e-51	176.0	COG0778@1|root,COG0778@2|Bacteria,1PDX3@1224|Proteobacteria,2VNSD@28216|Betaproteobacteria,37268@32003|Nitrosomonadales	28216|Betaproteobacteria	C	Nitroreductase family	moeY	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
k141_2559_2	118161.KB235922_gene570	5.2e-25	105.0	COG3321@1|root,COG3321@2|Bacteria,1FZXE@1117|Cyanobacteria	1117|Cyanobacteria	Q	Beta-ketoacyl synthase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	ADH_zinc_N_2,Acyl_transf_1,KAsynt_C_assoc,KR,Ketoacyl-synt_C,PP-binding,PS-DH,Sulfotransfer_3,Thioesterase,ketoacyl-synt
k141_2559_3	69328.PVLB_15335	1.26e-19	87.8	COG3208@1|root,COG3208@2|Bacteria,1RGYT@1224|Proteobacteria,1S89U@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	Thioesterase	-	-	-	-	-	-	-	-	-	-	-	-	Thioesterase
k141_3976_2	1121396.KB893123_gene1072	9.69e-60	197.0	COG1496@1|root,COG1496@2|Bacteria,1MW2H@1224|Proteobacteria,42SE9@68525|delta/epsilon subdivisions,2WMQE@28221|Deltaproteobacteria,2MJIU@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Belongs to the multicopper oxidase YfiH RL5 family	-	-	-	ko:K05810	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase_4
k141_3976_3	338963.Pcar_0112	2.79e-81	252.0	COG0388@1|root,COG0388@2|Bacteria,1MUUB@1224|Proteobacteria,42QTI@68525|delta/epsilon subdivisions,2WMRH@28221|Deltaproteobacteria,43SYN@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	-	-	3.5.1.3	ko:K13566	ko00250,map00250	-	R00269,R00348	RC00010	ko00000,ko00001,ko01000	-	-	-	CN_hydrolase
k141_5249_1	1479237.JMLY01000001_gene3311	3.84e-186	550.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,1RMYC@1236|Gammaproteobacteria,464UX@72275|Alteromonadaceae	1236|Gammaproteobacteria	P	COG0474 Cation transport ATPase	-	-	-	-	-	-	-	-	-	-	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase
k141_5249_2	1116375.VEJY3_20391	9.22e-36	122.0	COG0236@1|root,COG0236@2|Bacteria,1NHIC@1224|Proteobacteria,1SGKM@1236|Gammaproteobacteria	1236|Gammaproteobacteria	IQ	Phosphopantetheine attachment site	-	-	-	-	-	-	-	-	-	-	-	-	PP-binding
k141_2560_1	33035.JPJF01000098_gene1762	6.62e-72	224.0	COG1082@1|root,COG1082@2|Bacteria,1UZXE@1239|Firmicutes,24ECM@186801|Clostridia	186801|Clostridia	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
k141_4969_2	398579.Spea_0052	3.41e-63	203.0	COG1083@1|root,COG1083@2|Bacteria,1QACI@1224|Proteobacteria,1RR92@1236|Gammaproteobacteria,2QBW4@267890|Shewanellaceae	1236|Gammaproteobacteria	M	Acylneuraminate cytidylyltransferase	neuA	-	2.7.7.43,2.7.7.82	ko:K00983,ko:K18431	ko00520,ko01100,map00520,map01100	-	R01117,R04215,R10182	RC00152	ko00000,ko00001,ko01000	-	-	-	CTP_transf_3
k141_625_2	1121396.KB893104_gene1787	8.49e-141	407.0	COG0031@1|root,COG0031@2|Bacteria,1MUBE@1224|Proteobacteria,42N1R@68525|delta/epsilon subdivisions,2WJ7R@28221|Deltaproteobacteria,2MHWB@213118|Desulfobacterales	28221|Deltaproteobacteria	E	TIGRFAM cysteine synthase A	-	-	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
k141_625_3	649747.HMPREF0083_00863	2.9e-65	207.0	COG3208@1|root,COG3208@2|Bacteria,1TSW6@1239|Firmicutes,4HGXG@91061|Bacilli,26ZPT@186822|Paenibacillaceae	91061|Bacilli	Q	Thioesterase domain	-	-	-	-	-	-	-	-	-	-	-	-	Thioesterase
k141_4680_1	1348635.BBJY01000005_gene3293	3.45e-123	354.0	COG0670@1|root,COG0670@2|Bacteria,1MU69@1224|Proteobacteria,1RRVZ@1236|Gammaproteobacteria,1XTWT@135623|Vibrionales	135623|Vibrionales	S	Belongs to the BI1 family	yccA	-	-	ko:K19416	-	M00742	-	-	ko00000,ko00002,ko02000	1.A.14.2.1	-	-	Bax1-I
k141_4680_3	1238450.VIBNISOn1_720002	1.33e-46	150.0	COG4453@1|root,COG4453@2|Bacteria,1N3ZY@1224|Proteobacteria,1S97E@1236|Gammaproteobacteria,1XYBN@135623|Vibrionales	135623|Vibrionales	S	Protein of unknown function (DUF1778)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1778
k141_4680_4	1238450.VIBNISOn1_720003	9.09e-40	135.0	COG0454@1|root,COG0454@2|Bacteria,1QUS5@1224|Proteobacteria,1RRHY@1236|Gammaproteobacteria,1XVWU@135623|Vibrionales	135623|Vibrionales	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_10
k141_2298_2	1348635.BBJY01000005_gene3331	1.47e-147	431.0	COG0154@1|root,COG0154@2|Bacteria,1MU51@1224|Proteobacteria,1RR6N@1236|Gammaproteobacteria,1XY2Y@135623|Vibrionales	135623|Vibrionales	J	Amidase	-	-	3.5.1.4	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	-	R02540,R03096,R03180,R03909,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000	-	-	-	Amidase
k141_2298_3	1348635.BBJY01000005_gene3330	1.38e-245	689.0	COG0405@1|root,COG0405@2|Bacteria,1MUV6@1224|Proteobacteria,1RMIT@1236|Gammaproteobacteria,1XWE1@135623|Vibrionales	135623|Vibrionales	E	Gamma-glutamyltranspeptidase	-	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
k141_2298_4	1348635.BBJY01000005_gene3329	2.09e-252	698.0	COG0075@1|root,COG0075@2|Bacteria,1MWHJ@1224|Proteobacteria,1RMNR@1236|Gammaproteobacteria,1XWNK@135623|Vibrionales	135623|Vibrionales	E	Aminotransferase class-V	-	-	2.6.1.112	ko:K00839	ko00230,map00230	-	R10908	RC00018,RC03305	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_5
k141_2298_5	1348635.BBJY01000005_gene3328	2.67e-70	226.0	COG0624@1|root,COG0624@2|Bacteria,1MVUX@1224|Proteobacteria,1RPPD@1236|Gammaproteobacteria,1XV99@135623|Vibrionales	135623|Vibrionales	E	Peptidase family M20/M25/M40	-	-	3.5.3.9	ko:K02083	ko00230,ko01120,map00230,map01120	-	R02423	RC00064	ko00000,ko00001,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
k141_5251_1	1121405.dsmv_1727	1.4e-55	179.0	COG0461@1|root,COG0461@2|Bacteria,1PI8N@1224|Proteobacteria,42QSR@68525|delta/epsilon subdivisions,2WMT5@28221|Deltaproteobacteria,2MJH0@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	pyrE	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran
k141_1989_1	177437.HRM2_35320	3.26e-09	57.4	COG0664@1|root,COG0664@2|Bacteria,1NEQS@1224|Proteobacteria,42V5E@68525|delta/epsilon subdivisions,2WSDR@28221|Deltaproteobacteria,2MMFE@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Cyclic nucleotide-monophosphate binding domain	-	-	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	cNMP_binding
k141_1989_2	690850.Desaf_3637	9.87e-152	456.0	COG0651@1|root,COG0651@2|Bacteria,1MV6V@1224|Proteobacteria,42MSA@68525|delta/epsilon subdivisions,2WIS1@28221|Deltaproteobacteria,2M92C@213115|Desulfovibrionales	28221|Deltaproteobacteria	CP	PFAM NADH Ubiquinone plastoquinone (complex I)	-	-	-	ko:K05568,ko:K12137	-	-	-	-	ko00000,ko01000,ko02000	2.A.63.1,2.A.63.2	-	-	Proton_antipo_M
k141_1989_4	177437.HRM2_35350	8.97e-30	117.0	COG0651@1|root,COG0651@2|Bacteria,1QU5Z@1224|Proteobacteria,42MDX@68525|delta/epsilon subdivisions,2WJ56@28221|Deltaproteobacteria,2MIB7@213118|Desulfobacterales	28221|Deltaproteobacteria	CP	PFAM NADH Ubiquinone plastoquinone (complex I)	-	-	-	ko:K05568	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	Proton_antipo_M,Proton_antipo_N
k141_2562_1	706587.Desti_1908	1.61e-14	82.0	COG2204@1|root,COG3290@1|root,COG3829@1|root,COG2204@2|Bacteria,COG3290@2|Bacteria,COG3829@2|Bacteria,1MU0N@1224|Proteobacteria	1224|Proteobacteria	T	Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains	fgrM	-	-	ko:K07712,ko:K07713,ko:K07714	ko02020,map02020	M00497,M00499,M00500	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
k141_2874_1	598467.BrE312_1473	1.77e-141	422.0	COG2199@1|root,COG3706@2|Bacteria,1N9PI@1224|Proteobacteria,1RPY9@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,dCache_1
k141_4681_1	502025.Hoch_0419	3.25e-09	61.6	COG4558@1|root,COG4558@2|Bacteria,1QTSV@1224|Proteobacteria,43CYE@68525|delta/epsilon subdivisions	1224|Proteobacteria	P	Periplasmic binding protein	hmuT	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
k141_4681_2	357809.Cphy_2394	4.46e-30	120.0	COG1120@1|root,COG1120@2|Bacteria,1TP2Q@1239|Firmicutes,2492Z@186801|Clostridia,21XZ3@1506553|Lachnoclostridium	186801|Clostridia	HP	ATPases associated with a variety of cellular activities	-	-	3.6.3.34	ko:K02013	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	ABC_tran
k141_2563_1	1301098.PKB_0789	1.07e-22	102.0	COG2304@1|root,COG2304@2|Bacteria,1QWI7@1224|Proteobacteria,1T2VU@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Putative phage tail protein	-	-	-	-	-	-	-	-	-	-	-	-	Phage-tail_3
k141_3264_1	1219065.VPR01S_03_01710	4.53e-143	412.0	COG2855@1|root,COG2855@2|Bacteria,1MVIP@1224|Proteobacteria,1RPSG@1236|Gammaproteobacteria,1XTQB@135623|Vibrionales	135623|Vibrionales	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	Cons_hypoth698
k141_3264_3	870967.VIS19158_19847	7.67e-135	399.0	COG0318@1|root,COG0318@2|Bacteria,1MW0Y@1224|Proteobacteria,1RN35@1236|Gammaproteobacteria,1XTBP@135623|Vibrionales	135623|Vibrionales	IQ	O-succinylbenzoic acid--CoA ligase	menE	-	6.2.1.26	ko:K01911	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R04030	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	AMP-binding,AMP-binding_C
k141_2299_1	1051646.VITU9109_07533	2.8e-23	99.8	COG1030@1|root,COG1030@2|Bacteria,1MUJN@1224|Proteobacteria,1RN3U@1236|Gammaproteobacteria,1XV48@135623|Vibrionales	135623|Vibrionales	O	COG1030 Membrane-bound serine protease (ClpP class)	-	-	-	ko:K07403	-	-	-	-	ko00000	-	-	-	NfeD
k141_2299_2	1265503.KB905170_gene40	7.5e-136	390.0	COG0330@1|root,COG0330@2|Bacteria,1MUM8@1224|Proteobacteria,1RNW8@1236|Gammaproteobacteria,2Q5ZV@267889|Colwelliaceae	1236|Gammaproteobacteria	O	prohibitin homologues	qmcA	-	-	-	-	-	-	-	-	-	-	-	Band_7
k141_5252_1	795359.TOPB45_1061	1.77e-62	204.0	COG1578@1|root,COG1578@2|Bacteria,2GI1W@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	S	Protein of unknown function DUF89	-	-	-	ko:K09116	-	-	-	-	ko00000	-	-	-	DUF89
k141_3978_1	933262.AXAM01000023_gene647	7.36e-95	300.0	COG0544@1|root,COG0544@2|Bacteria,1MUJP@1224|Proteobacteria,42MBB@68525|delta/epsilon subdivisions,2WIU1@28221|Deltaproteobacteria,2MHZ5@213118|Desulfobacterales	28221|Deltaproteobacteria	D	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C,Trigger_N
k141_2081_1	722419.PH505_ai00080	4.16e-125	379.0	COG0397@1|root,COG0397@2|Bacteria,1MVK3@1224|Proteobacteria,1RNCS@1236|Gammaproteobacteria,2PZRB@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	S	Belongs to the UPF0061 (SELO) family	ydiU	-	-	-	-	-	-	-	-	-	-	-	UPF0061
k141_2081_2	999423.HMPREF9161_01801	7.08e-82	258.0	COG2040@1|root,COG2040@2|Bacteria,1UHQ5@1239|Firmicutes,4H2U3@909932|Negativicutes	909932|Negativicutes	H	homocysteine S-methyltransferase	mmuM	-	2.1.1.10	ko:K00547	ko00270,ko01100,ko01110,map00270,map01100,map01110	-	R00650	RC00003,RC00035	ko00000,ko00001,ko01000	-	-	-	S-methyl_trans
k141_2081_3	1348635.BBJY01000015_gene674	2.26e-179	501.0	COG0834@1|root,COG0834@2|Bacteria,1MWDK@1224|Proteobacteria,1RZMR@1236|Gammaproteobacteria,1XTN8@135623|Vibrionales	135623|Vibrionales	ET	belongs to the bacterial solute-binding protein 3 family	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
k141_2081_4	675815.VOA_000998	2.03e-140	405.0	COG0697@1|root,COG0697@2|Bacteria,1MWSU@1224|Proteobacteria,1RSF8@1236|Gammaproteobacteria,1XTMR@135623|Vibrionales	135623|Vibrionales	EG	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily	-	-	-	-	-	-	-	-	-	-	-	-	EamA
k141_2081_5	1051646.VITU9109_16588	1.14e-112	328.0	COG3155@1|root,COG3155@2|Bacteria,1MW2K@1224|Proteobacteria,1RMDJ@1236|Gammaproteobacteria,1XVK8@135623|Vibrionales	135623|Vibrionales	Q	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate	elbB	-	-	-	-	-	-	-	-	-	-	-	DJ-1_PfpI
k141_2081_6	357804.Ping_0275	9.92e-52	174.0	COG2207@1|root,COG2207@2|Bacteria,1Q3UX@1224|Proteobacteria,1RS88@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	transcriptional regulator	eutR	GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006089,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009059,GO:0009438,GO:0009987,GO:0010467,GO:0016053,GO:0016070,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019172,GO:0019243,GO:0019249,GO:0019438,GO:0019752,GO:0032774,GO:0032787,GO:0034641,GO:0034645,GO:0034654,GO:0042180,GO:0042182,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046185,GO:0046394,GO:0046483,GO:0051596,GO:0061727,GO:0071704,GO:0072330,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901575,GO:1901576,GO:1901615,GO:1901617	-	ko:K04033	-	-	-	-	ko00000,ko03000	-	-	-	HTH_18
k141_427_1	1304885.AUEY01000012_gene1828	1.68e-137	397.0	COG1032@1|root,COG1032@2|Bacteria,1P9J0@1224|Proteobacteria,42MWG@68525|delta/epsilon subdivisions,2WIV5@28221|Deltaproteobacteria,2MI1A@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM Radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
k141_427_2	1196324.A374_04874	1.72e-61	207.0	COG0021@1|root,COG0021@2|Bacteria,1TPIB@1239|Firmicutes,4HADA@91061|Bacilli	91061|Bacilli	G	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate	tkt	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
k141_2082_1	1121890.AUDO01000005_gene1550	1.28e-81	272.0	COG0642@1|root,COG2205@2|Bacteria,4NDXU@976|Bacteroidetes,1HYZK@117743|Flavobacteriia,2NUWE@237|Flavobacterium	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,Hpt,PAS_3,PAS_9,Response_reg
k141_3114_1	1348635.BBJY01000017_gene4178	2.15e-155	446.0	COG2038@1|root,COG2038@2|Bacteria,1MVAM@1224|Proteobacteria,1RNPV@1236|Gammaproteobacteria,1XTQH@135623|Vibrionales	135623|Vibrionales	F	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB)	cobT	GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008939,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0017144,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042364,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.4.2.21	ko:K00768	ko00860,ko01100,map00860,map01100	M00122	R04148	RC00033,RC00063	ko00000,ko00001,ko00002,ko01000	-	-	-	DBI_PRT
k141_3114_2	1517681.HW45_18160	4.4e-259	719.0	COG2925@1|root,COG2925@2|Bacteria,1MV0U@1224|Proteobacteria,1RM85@1236|Gammaproteobacteria,1XT1P@135623|Vibrionales	135623|Vibrionales	L	COG2925 Exonuclease I	sbcB	-	3.1.11.1	ko:K01141	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_X-T_C,RNase_T
k141_3114_3	243277.VC_1233	1.13e-40	138.0	COG1380@1|root,COG1380@2|Bacteria,1NAY3@1224|Proteobacteria,1SD5V@1236|Gammaproteobacteria,1XXEH@135623|Vibrionales	135623|Vibrionales	S	effector of murein hydrolase LrgA	-	-	-	ko:K06518	-	-	-	-	ko00000,ko02000	1.E.14.2	-	-	LrgA
k141_3114_4	345073.VC395_1351	1.58e-52	172.0	COG1346@1|root,COG1346@2|Bacteria,1MV81@1224|Proteobacteria,1RS5C@1236|Gammaproteobacteria,1XT9T@135623|Vibrionales	135623|Vibrionales	M	effector of murein hydrolase	yohK	-	-	-	-	-	-	-	-	-	-	-	LrgB
k141_3116_1	883126.HMPREF9710_00129	1.4e-60	207.0	COG0443@1|root,COG0443@2|Bacteria,1MXX7@1224|Proteobacteria,2VJ41@28216|Betaproteobacteria,47652@75682|Oxalobacteraceae	28216|Betaproteobacteria	O	Hsp70 protein	-	-	-	-	-	-	-	-	-	-	-	-	HSP70
k141_123_1	575788.VS_II0140	2.86e-65	203.0	COG2731@1|root,COG2731@2|Bacteria,1RCDU@1224|Proteobacteria,1S4CF@1236|Gammaproteobacteria,1XYS4@135623|Vibrionales	135623|Vibrionales	G	Domain of unknown function (DUF386)	yhcH	-	-	-	-	-	-	-	-	-	-	-	DUF386
k141_123_2	298386.PBPRB0275	1.16e-130	374.0	COG0235@1|root,COG0235@2|Bacteria,1MU54@1224|Proteobacteria,1RMIP@1236|Gammaproteobacteria,1XUM8@135623|Vibrionales	135623|Vibrionales	G	COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases	araD	-	5.1.3.4	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	M00550	R05850	RC01479	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldolase_II
k141_123_3	617140.AJZE01000008_gene3473	3.14e-168	477.0	COG1638@1|root,COG1638@2|Bacteria,1MVHC@1224|Proteobacteria,1RPNJ@1236|Gammaproteobacteria,1XU8W@135623|Vibrionales	135623|Vibrionales	G	TRAP-type C4-dicarboxylate transport system, periplasmic component	-	-	-	ko:K21395	-	-	-	-	ko00000,ko02000	2.A.56.1	-	-	DctP
k141_123_4	617140.AJZE01000008_gene3472	2.05e-245	681.0	COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,1RNAM@1236|Gammaproteobacteria,1XTIW@135623|Vibrionales	135623|Vibrionales	G	TRAP-type C4-dicarboxylate transport system, large permease component	-	-	-	ko:K21393	-	-	-	-	ko00000,ko02000	2.A.56.1	-	-	DctM
k141_3119_1	1304885.AUEY01000012_gene1788	4.15e-58	183.0	COG1846@1|root,COG1846@2|Bacteria,1PC0J@1224|Proteobacteria,42TS6@68525|delta/epsilon subdivisions,2WQ2S@28221|Deltaproteobacteria,2MKQQ@213118|Desulfobacterales	28221|Deltaproteobacteria	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
k141_430_2	1190603.AJYD01000005_gene4015	5.42e-129	388.0	COG2801@1|root,COG2801@2|Bacteria	2|Bacteria	L	transposition	-	-	-	ko:K07483,ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,Tn7_Tnp_TnsA_N
k141_430_3	1051646.VITU9109_16613	3.78e-46	149.0	COG3609@1|root,COG3609@2|Bacteria,1N9NJ@1224|Proteobacteria,1SCVS@1236|Gammaproteobacteria,1XYCV@135623|Vibrionales	135623|Vibrionales	K	Bacterial antitoxin of ParD toxin-antitoxin type II system and RHH	-	-	-	ko:K07746	-	-	-	-	ko00000,ko02048	-	-	-	ParD_antitoxin
k141_430_5	675813.VIB_000994	1.66e-16	79.3	COG5433@1|root,COG5433@2|Bacteria,1MXB5@1224|Proteobacteria,1RSAV@1236|Gammaproteobacteria,1XWBQ@135623|Vibrionales	135623|Vibrionales	L	DDE_Tnp_1-associated	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_assoc
k141_430_6	392500.Swoo_3496	1.87e-123	361.0	COG3547@1|root,COG3547@2|Bacteria,1MXKJ@1224|Proteobacteria,1RSCP@1236|Gammaproteobacteria,2QBDW@267890|Shewanellaceae	1236|Gammaproteobacteria	L	Transposase IS116/IS110/IS902 family	Z012_08285	-	-	ko:K07486	-	-	-	-	ko00000	-	-	-	DEDD_Tnp_IS110,Transposase_20
k141_430_8	1565129.JSFF01000017_gene2866	3.4e-82	251.0	COG0515@1|root,COG0515@2|Bacteria,1QZ10@1224|Proteobacteria,1S5Y1@1236|Gammaproteobacteria,2QDMF@267890|Shewanellaceae	1236|Gammaproteobacteria	KLT	Domain of unknown function (DUF4328)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4328
k141_3494_2	243277.VC_0847	2.78e-227	635.0	COG0582@1|root,COG0582@2|Bacteria,1MU23@1224|Proteobacteria,1RMJ1@1236|Gammaproteobacteria,1XTXF@135623|Vibrionales	135623|Vibrionales	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Arm-DNA-bind_3,Phage_int_SAM_3,Phage_integrase
k141_3494_3	1051646.VITU9109_08922	1.34e-10	57.8	COG3311@1|root,COG3311@2|Bacteria,1NGB9@1224|Proteobacteria,1SGDV@1236|Gammaproteobacteria,1XZ0B@135623|Vibrionales	135623|Vibrionales	K	Transcriptional regulator	-	-	-	ko:K07733	-	-	-	-	ko00000,ko03000	-	-	-	Phage_AlpA
k141_3494_4	1051646.VITU9109_07789	3.11e-259	733.0	COG0305@1|root,COG0305@2|Bacteria,1QXDP@1224|Proteobacteria,1T398@1236|Gammaproteobacteria,1XYGQ@135623|Vibrionales	135623|Vibrionales	L	Uncharacterized conserved protein (DUF2075)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2075
k141_3494_5	545694.TREPR_2838	8.86e-39	134.0	COG0494@1|root,COG0494@2|Bacteria,2JBHX@203691|Spirochaetes	203691|Spirochaetes	L	hmm pf00293	-	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
k141_3494_6	309798.COPRO5265_1437	4.42e-16	90.5	COG0286@1|root,COG0732@1|root,COG0286@2|Bacteria,COG0732@2|Bacteria,1USGX@1239|Firmicutes,24J6H@186801|Clostridia	186801|Clostridia	L	Type I restriction	-	-	3.1.21.3	ko:K01154	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	Methylase_S
k141_3494_8	911008.GLAD_02899	6.26e-137	419.0	COG1132@1|root,COG1132@2|Bacteria,1R5YA@1224|Proteobacteria,1RZJT@1236|Gammaproteobacteria	1236|Gammaproteobacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	-	-	-	-	-	-	-	-	-	AAA_21
k141_3494_9	319224.Sputcn32_3986	0.0	1807.0	COG0610@1|root,COG0610@2|Bacteria,1MU96@1224|Proteobacteria,1RP2Q@1236|Gammaproteobacteria,2QA0Z@267890|Shewanellaceae	1236|Gammaproteobacteria	V	Subunit R is required for both nuclease and ATPase activities, but not for modification	-	-	3.1.21.3	ko:K01153	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	DUF3387,HSDR_N,ResIII
k141_3494_10	1286106.MPL1_08007	2.56e-90	283.0	COG0732@1|root,COG0732@2|Bacteria,1R5R8@1224|Proteobacteria,1S9TA@1236|Gammaproteobacteria	1236|Gammaproteobacteria	V	COG0732 Restriction endonuclease S subunits	-	-	3.1.21.3	ko:K01154	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	Methylase_S
k141_3494_11	740709.A10D4_04837	4.17e-316	866.0	COG0286@1|root,COG0286@2|Bacteria,1MW3A@1224|Proteobacteria,1RMRA@1236|Gammaproteobacteria,2QG1G@267893|Idiomarinaceae	1236|Gammaproteobacteria	V	Type I restriction-modification system methyltransferase subunit	-	-	2.1.1.72	ko:K03427	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HsdM_N,N6_Mtase
k141_3494_12	391615.ABSJ01000027_gene219	0.0	870.0	COG0286@1|root,COG0286@2|Bacteria,1MW3A@1224|Proteobacteria,1RMRA@1236|Gammaproteobacteria,1J5H0@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	V	Type I restriction-modification system	-	-	2.1.1.72	ko:K03427	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HsdM_N,N6_Mtase
k141_3494_13	1122207.MUS1_09570	4.09e-31	109.0	COG3311@1|root,COG3311@2|Bacteria,1N72I@1224|Proteobacteria,1SDJ2@1236|Gammaproteobacteria,1XMSA@135619|Oceanospirillales	135619|Oceanospirillales	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
k141_3494_14	870967.VIS19158_13942	9.77e-59	186.0	COG0328@1|root,COG0328@2|Bacteria,1P13X@1224|Proteobacteria,1SSVM@1236|Gammaproteobacteria,1Y2UD@135623|Vibrionales	135623|Vibrionales	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	-	-	3.1.26.4	ko:K03469	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_H
k141_3494_15	94122.Shewana3_1804	1.54e-65	204.0	COG2003@1|root,COG2003@2|Bacteria,1MXZ5@1224|Proteobacteria,1S5A5@1236|Gammaproteobacteria,2QBU9@267890|Shewanellaceae	1236|Gammaproteobacteria	L	PFAM DNA repair protein RadC	-	-	-	ko:K03630	-	-	-	-	ko00000	-	-	-	RadC
k141_3494_17	1114922.CIFAM_06_00110	1.09e-28	104.0	COG1396@1|root,COG1396@2|Bacteria,1N8RD@1224|Proteobacteria,1SEFV@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	Antitoxin component of a type II toxin-antitoxin (TA) system. Neutralizes the toxic effect of cognate toxin HipA. Also neutralizes the toxic effect of non- cognate toxin YjjJ. Binds to operator sites with the consensus sequence 5-'TATCCN(8)GGATA-3' to repress the hipBA operon promoter	hipB	GO:0000976,GO:0000984,GO:0000985,GO:0001017,GO:0001046,GO:0001047,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032774,GO:0032991,GO:0032993,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043565,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0045892,GO:0045934,GO:0046483,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141	-	ko:K15773	-	-	-	-	ko00000,ko02048,ko03000	-	-	-	HTH_3
k141_3494_18	675817.VDA_002790	2.7e-18	82.8	COG3550@1|root,COG3550@2|Bacteria,1MVAB@1224|Proteobacteria,1RR5N@1236|Gammaproteobacteria,1XW4A@135623|Vibrionales	135623|Vibrionales	S	Pfam:HipA_N	hipA	-	2.7.11.1	ko:K07154	-	-	-	-	ko00000,ko01000,ko01001,ko02048	-	-	-	Couple_hipA,HipA_C
k141_126_1	1304885.AUEY01000013_gene3141	5.63e-189	539.0	COG0427@1|root,COG0427@2|Bacteria,1MUGE@1224|Proteobacteria,42MHC@68525|delta/epsilon subdivisions,2WINZ@28221|Deltaproteobacteria,2MI87@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM Acetyl-CoA hydrolase transferase	-	-	-	-	-	-	-	-	-	-	-	-	AcetylCoA_hyd_C,AcetylCoA_hydro,Acetyltransf_1
k141_126_2	247490.KSU1_B0159	8.07e-69	247.0	COG2203@1|root,COG4191@1|root,COG2203@2|Bacteria,COG4191@2|Bacteria,2IWUM@203682|Planctomycetes	203682|Planctomycetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
k141_3495_1	177437.HRM2_02690	3.43e-57	193.0	COG0303@1|root,COG0303@2|Bacteria,1MVD5@1224|Proteobacteria,42M5U@68525|delta/epsilon subdivisions,2WJ06@28221|Deltaproteobacteria,2MHZ7@213118|Desulfobacterales	28221|Deltaproteobacteria	H	TIGRFAM molybdenum cofactor synthesis domain	-	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
k141_3495_2	457570.Nther_0447	1.58e-41	155.0	COG0303@1|root,COG1910@1|root,COG0303@2|Bacteria,COG1910@2|Bacteria,1TRH3@1239|Firmicutes,24ATZ@186801|Clostridia	186801|Clostridia	P	binding domain	-	-	2.10.1.1	ko:K03750,ko:K07219	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N,PBP_like
k141_431_1	904296.HMPREF9124_0592	3.67e-37	135.0	COG0491@1|root,COG0491@2|Bacteria,1V6FA@1239|Firmicutes,24JGV@186801|Clostridia,2PRQ3@265975|Oribacterium	186801|Clostridia	S	Metallo-beta-lactamase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
k141_431_2	935845.JADQ01000044_gene3145	5e-05	52.4	COG0834@1|root,COG0834@2|Bacteria,1TT11@1239|Firmicutes,4HAHV@91061|Bacilli,26SQB@186822|Paenibacillaceae	91061|Bacilli	ET	Amino acid ABC transporter substrate-binding protein	glnH	-	-	ko:K10039	ko02010,map02010	M00228	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
k141_3120_2	1348635.BBJY01000009_gene1582	2.47e-99	292.0	COG2249@1|root,COG2249@2|Bacteria,1MXFT@1224|Proteobacteria,1RMVS@1236|Gammaproteobacteria,1XTQK@135623|Vibrionales	135623|Vibrionales	C	Regulatory subunit of a potassium efflux system that confers protection against electrophiles. Required for full activity of KefB	kefG	-	-	ko:K11748	-	-	-	-	ko00000,ko02000	2.A.37.1.2	-	-	Flavodoxin_2
k141_3496_1	1121396.KB893062_gene2735	3.33e-25	99.8	COG2207@1|root,COG2207@2|Bacteria,1NDY5@1224|Proteobacteria,43ARA@68525|delta/epsilon subdivisions,2X659@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
k141_3496_2	1121396.KB893062_gene2734	1.23e-39	133.0	2DTV6@1|root,32UW0@2|Bacteria,1NM1T@1224|Proteobacteria,42Y2A@68525|delta/epsilon subdivisions,2WT8Y@28221|Deltaproteobacteria,2MP2W@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_4119_3	298386.PBPRB1874	8.31e-216	603.0	COG1312@1|root,COG1312@2|Bacteria,1MWYD@1224|Proteobacteria,1RR0Q@1236|Gammaproteobacteria,1XU49@135623|Vibrionales	135623|Vibrionales	G	Catalyzes the dehydration of D-mannonate	uxuA	-	4.2.1.8	ko:K01686	ko00040,ko01100,map00040,map01100	M00061	R05606	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	-	UxuA
k141_4119_4	1517681.HW45_14075	1.16e-118	346.0	COG2186@1|root,COG2186@2|Bacteria,1MY1K@1224|Proteobacteria,1RMUE@1236|Gammaproteobacteria,1XVWP@135623|Vibrionales	135623|Vibrionales	K	COG2186 Transcriptional regulators	uxuR	-	-	ko:K13637	-	-	-	-	ko00000,ko03000	-	-	-	FCD,GntR
k141_4119_5	1517681.HW45_14085	5.48e-173	489.0	COG1638@1|root,COG1638@2|Bacteria,1MVHC@1224|Proteobacteria,1RPNJ@1236|Gammaproteobacteria,1XU8W@135623|Vibrionales	135623|Vibrionales	G	TRAP-type C4-dicarboxylate transport system, periplasmic component	-	-	-	ko:K11688	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.56.1	-	-	DctP
k141_4119_6	1517681.HW45_14090	3.83e-66	206.0	COG3090@1|root,COG3090@2|Bacteria,1RJ8K@1224|Proteobacteria,1SA02@1236|Gammaproteobacteria,1XUQB@135623|Vibrionales	135623|Vibrionales	G	TRAP-type C4-dicarboxylate transport system, small permease component	-	-	-	-	-	-	-	-	-	-	-	-	DctQ
k141_4119_7	1517681.HW45_14095	2.41e-259	717.0	COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,1RNAM@1236|Gammaproteobacteria,1XTIW@135623|Vibrionales	135623|Vibrionales	G	TRAP-type C4-dicarboxylate transport system, large permease component	-	-	-	-	-	-	-	-	-	-	-	-	DctM
k141_4119_8	1517681.HW45_14100	0.0	1147.0	COG1501@1|root,COG1501@2|Bacteria,1MWNJ@1224|Proteobacteria,1RMJ9@1236|Gammaproteobacteria,1XVZW@135623|Vibrionales	135623|Vibrionales	G	Belongs to the glycosyl hydrolase 31 family	-	-	3.2.1.20	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00028,R00801,R00802,R06087,R06088	RC00028,RC00049,RC00077	ko00000,ko00001,ko01000	-	GH31	-	DUF4968,DUF5110,Glyco_hydro_31
k141_4119_9	675815.VOA_001229	2.62e-233	655.0	COG0246@1|root,COG0246@2|Bacteria,1MVZ7@1224|Proteobacteria,1RNIZ@1236|Gammaproteobacteria,1XV89@135623|Vibrionales	135623|Vibrionales	C	COG0246 Mannitol-1-phosphate altronate dehydrogenases	uxuB	-	1.1.1.57	ko:K00040	ko00040,ko01100,map00040,map01100	M00061	R02454	RC00085	ko00000,ko00001,ko00002,ko01000	-	-	-	Mannitol_dh,Mannitol_dh_C
k141_4119_10	675815.VOA_001228	1.32e-258	718.0	COG1904@1|root,COG1904@2|Bacteria,1MVRI@1224|Proteobacteria,1RMRR@1236|Gammaproteobacteria,1XTDU@135623|Vibrionales	135623|Vibrionales	G	glucuronate isomerase activity	uxaC	-	5.3.1.12	ko:K01812	ko00040,ko01100,map00040,map01100	M00061,M00631	R01482,R01983	RC00376	ko00000,ko00001,ko00002,ko01000	-	-	-	UxaC
k141_4119_11	1116375.VEJY3_18296	1.16e-226	655.0	COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,1MU9U@1224|Proteobacteria,1RNKA@1236|Gammaproteobacteria	1236|Gammaproteobacteria	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses	nadE	-	6.3.1.5,6.3.5.1	ko:K01916,ko:K01950	ko00760,ko01100,map00760,map01100	M00115	R00189,R00257	RC00010,RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase,NAD_synthase
k141_4119_12	945550.VISI1226_01680	7.98e-54	170.0	COG0023@1|root,COG0023@2|Bacteria,1MZ8T@1224|Proteobacteria,1S929@1236|Gammaproteobacteria,1XXTP@135623|Vibrionales	135623|Vibrionales	J	COG0023 Translation initiation factor 1 (eIF-1 SUI1) and related proteins	yciH	-	-	ko:K03113	ko03013,map03013	-	-	-	ko00000,ko00001,ko03012	-	-	-	SUI1
k141_749_41	1280001.BAOA01000045_gene1690	4.53e-104	323.0	COG0845@1|root,COG0845@2|Bacteria,1R67N@1224|Proteobacteria,1RYPZ@1236|Gammaproteobacteria,1XST6@135623|Vibrionales	135623|Vibrionales	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_749_43	223926.28805327	2.89e-234	647.0	COG0473@1|root,COG0473@2|Bacteria,1MUH4@1224|Proteobacteria,1RMZQ@1236|Gammaproteobacteria,1XTG7@135623|Vibrionales	135623|Vibrionales	CE	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate	leuB	GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
k141_749_44	675806.VII_001374	1.11e-300	824.0	COG0065@1|root,COG0065@2|Bacteria,1MVYR@1224|Proteobacteria,1RMF6@1236|Gammaproteobacteria,1XT5K@135623|Vibrionales	135623|Vibrionales	H	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuC	GO:0003674,GO:0003824,GO:0003861,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009316,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase
k141_749_45	1188252.AJYK01000108_gene2268	6.88e-129	367.0	COG0066@1|root,COG0066@2|Bacteria,1MVXB@1224|Proteobacteria,1RNMK@1236|Gammaproteobacteria,1XT0W@135623|Vibrionales	135623|Vibrionales	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuD	GO:0003674,GO:0003824,GO:0003861,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009316,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494	4.2.1.33,4.2.1.35	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R10170	RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase_C
k141_1075_1	1348635.BBJY01000005_gene3302	1.52e-22	95.9	COG4603@1|root,COG4603@2|Bacteria,1MX6V@1224|Proteobacteria,1RS4S@1236|Gammaproteobacteria,1XWKM@135623|Vibrionales	1236|Gammaproteobacteria	S	Branched-chain amino acid transport system / permease component	IV02_22040	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
k141_1075_2	1348635.BBJY01000005_gene3303	8.88e-165	467.0	COG1079@1|root,COG1079@2|Bacteria,1MVDQ@1224|Proteobacteria,1RR75@1236|Gammaproteobacteria,1XU9Y@135623|Vibrionales	1236|Gammaproteobacteria	S	Branched-chain amino acid transport system / permease component	IV02_22045	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
k141_1075_3	1348635.BBJY01000005_gene3304	4.63e-197	553.0	COG1744@1|root,COG1744@2|Bacteria,1MWTM@1224|Proteobacteria,1RYCX@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	ABC-type transport system, periplasmic component surface lipoprotein	-	-	-	ko:K02058	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	Bmp
k141_1075_4	1348635.BBJY01000005_gene3310	1.88e-188	538.0	COG0402@1|root,COG0402@2|Bacteria,1MUPT@1224|Proteobacteria,1SYCI@1236|Gammaproteobacteria,1XTV5@135623|Vibrionales	135623|Vibrionales	F	COG0402 Cytosine deaminase and related metal-dependent hydrolases	guaD	-	3.5.4.3	ko:K01487	ko00230,ko01100,map00230,map01100	-	R01676	RC00204	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
k141_5132_1	485915.Dret_1767	4.73e-200	568.0	COG0733@1|root,COG0733@2|Bacteria,1MUZJ@1224|Proteobacteria,42M3J@68525|delta/epsilon subdivisions,2WJZA@28221|Deltaproteobacteria,2M9HI@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family	-	-	-	ko:K03308	-	-	-	-	ko00000	2.A.22.4,2.A.22.5	-	-	SNF
k141_1077_1	882083.SacmaDRAFT_3402	0.00021	48.5	COG1296@1|root,COG1296@2|Bacteria,2GN6R@201174|Actinobacteria,4E35S@85010|Pseudonocardiales	201174|Actinobacteria	E	Branched-chain amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	AzlC
k141_3133_1	1005058.UMN179_01236	9.64e-90	273.0	COG1349@1|root,COG1349@2|Bacteria,1NVBP@1224|Proteobacteria,1RXX5@1236|Gammaproteobacteria,1Y6UR@135625|Pasteurellales	135625|Pasteurellales	K	DeoR C terminal sensor domain	fucR	-	-	ko:K02430	-	-	-	-	ko00000,ko03000	-	-	-	DeoRC,HTH_DeoR
k141_3133_3	1205908.AKXW01000008_gene3227	2.14e-58	194.0	COG5421@1|root,COG5421@2|Bacteria,1R25F@1224|Proteobacteria,1RZQP@1236|Gammaproteobacteria,1XV94@135623|Vibrionales	135623|Vibrionales	L	Domain of unknown function (DUF4277)	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DUF4277
k141_145_2	37659.JNLN01000001_gene894	1.33e-95	297.0	COG0787@1|root,COG0787@2|Bacteria,1TNYY@1239|Firmicutes,2480T@186801|Clostridia,36ES8@31979|Clostridiaceae	186801|Clostridia	M	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	alr	-	5.1.1.1	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011	-	-	iHN637.CLJU_RS15830	Ala_racemase_C,Ala_racemase_N
k141_145_3	631362.Thi970DRAFT_02518	8.43e-34	127.0	COG4623@1|root,COG4623@2|Bacteria,1QUQJ@1224|Proteobacteria,1T218@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Transglycosylase SLT domain	-	-	-	-	-	-	-	-	-	-	-	-	SLT
k141_145_5	159749.K0SX91	4.84e-15	76.3	COG0183@1|root,KOG1389@2759|Eukaryota,2XAEH@2836|Bacillariophyta	2836|Bacillariophyta	I	Thiolase, N-terminal domain	-	-	2.3.1.16	ko:K07513	ko00071,ko00280,ko00592,ko01040,ko01100,ko01110,ko01130,ko01212,ko03320,ko04146,map00071,map00280,map00592,map01040,map01100,map01110,map01130,map01212,map03320,map04146	M00087,M00113	R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R07891,R07895,R07899,R07937,R07953	RC00004,RC00326,RC00405,RC01702,RC02728	ko00000,ko00001,ko00002,ko01000	-	-	-	Thiolase_C,Thiolase_N
k141_1435_1	96561.Dole_1767	4.65e-66	212.0	COG1186@1|root,COG1186@2|Bacteria,1MUAW@1224|Proteobacteria,42MKD@68525|delta/epsilon subdivisions,2WIZP@28221|Deltaproteobacteria,2MIG2@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	-	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
k141_1435_2	290315.Clim_1703	1.97e-18	87.4	COG0815@1|root,COG0815@2|Bacteria,1FDIC@1090|Chlorobi	1090|Chlorobi	M	Transfers the fatty acyl group on membrane lipoproteins	lnt	-	-	ko:K03820	-	-	-	-	ko00000,ko01000	-	GT2	-	CN_hydrolase
k141_3134_1	1348635.BBJY01000001_gene2431	1.68e-69	222.0	COG0119@1|root,COG0119@2|Bacteria,1MUNQ@1224|Proteobacteria,1RRGA@1236|Gammaproteobacteria,1Y0I3@135623|Vibrionales	135623|Vibrionales	E	HMGL-like	-	-	2.3.3.14	ko:K02594	ko00620,map00620	-	R00271	RC00004,RC00067,RC02754	ko00000,ko00001,ko01000	-	-	-	HMGL-like
k141_146_1	1121456.ATVA01000017_gene38	4.88e-39	142.0	COG0697@1|root,COG0697@2|Bacteria,1NS7A@1224|Proteobacteria,42MCJ@68525|delta/epsilon subdivisions,2WKQ4@28221|Deltaproteobacteria,2M94E@213115|Desulfovibrionales	28221|Deltaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
k141_4475_3	999411.HMPREF1092_00646	1.48e-18	82.0	COG1380@1|root,COG1380@2|Bacteria,1VEN4@1239|Firmicutes,24MMB@186801|Clostridia,36KP1@31979|Clostridiaceae	186801|Clostridia	S	LrgA family	lrgA	-	-	ko:K06518	-	-	-	-	ko00000,ko02000	1.E.14.2	-	-	LrgA
k141_4475_4	1196322.A370_03721	5.17e-67	213.0	COG1346@1|root,COG1346@2|Bacteria,1TRGN@1239|Firmicutes,24AGM@186801|Clostridia,36HZR@31979|Clostridiaceae	186801|Clostridia	M	PFAM LrgB family protein	lrgB	-	-	-	-	-	-	-	-	-	-	-	LrgB
k141_4475_6	913865.DOT_3444	6.23e-23	100.0	COG1522@1|root,COG1522@2|Bacteria,1V6TH@1239|Firmicutes,24JH9@186801|Clostridia,260KT@186807|Peptococcaceae	186801|Clostridia	K	transcriptional regulator, AsnC family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_AsnC-type
k141_4475_7	1121289.JHVL01000036_gene2566	3.25e-144	417.0	COG0535@1|root,COG0535@2|Bacteria,1TR52@1239|Firmicutes,247SB@186801|Clostridia,36E8H@31979|Clostridiaceae	186801|Clostridia	C	Radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM,SPASM
k141_4475_8	511.JT27_15580	1.28e-66	223.0	COG0535@1|root,COG0535@2|Bacteria,1MUQP@1224|Proteobacteria,2VJD9@28216|Betaproteobacteria,3T52S@506|Alcaligenaceae	28216|Betaproteobacteria	C	4Fe-4S single cluster domain	nirJ	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM,SPASM
k141_4475_9	1444309.JAQG01000140_gene1347	9.1e-19	99.0	COG0840@1|root,COG0840@2|Bacteria,1TP5A@1239|Firmicutes,4H9RZ@91061|Bacilli,26QU5@186822|Paenibacillaceae	91061|Bacilli	NT	chemotaxis protein	tlpA1	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,CHASE3,HAMP,MCPsignal
k141_4274_1	443144.GM21_0522	1.78e-41	139.0	COG0640@1|root,COG0640@2|Bacteria,1N2P4@1224|Proteobacteria,431S4@68525|delta/epsilon subdivisions,2WW72@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
k141_4274_2	177439.DP2914	2.55e-53	171.0	COG0454@1|root,COG0454@2|Bacteria,1N9YI@1224|Proteobacteria,42WD0@68525|delta/epsilon subdivisions,2WVKC@28221|Deltaproteobacteria,2MNK6@213118|Desulfobacterales	28221|Deltaproteobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_10,Acetyltransf_7
k141_4274_3	1190603.AJYD01000076_gene2562	2.04e-57	181.0	COG0645@1|root,COG0645@2|Bacteria,1RDGW@1224|Proteobacteria,1S7GV@1236|Gammaproteobacteria,1Y0GA@135623|Vibrionales	135623|Vibrionales	S	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_33
k141_3646_1	1121440.AUMA01000014_gene1919	2.23e-19	87.0	COG0765@1|root,COG0765@2|Bacteria,1MV3I@1224|Proteobacteria,42Q6W@68525|delta/epsilon subdivisions,2WKMV@28221|Deltaproteobacteria,2M8AI@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	TIGRFAM polar amino acid ABC transporter, inner membrane subunit	-	-	-	ko:K02029,ko:K10002	ko02010,ko02020,map02010,map02020	M00230,M00236	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3,3.A.1.3.19,3.A.1.3.4	-	-	BPD_transp_1
k141_3646_2	690850.Desaf_3371	1.19e-48	162.0	COG0252@1|root,COG0252@2|Bacteria,1RHAW@1224|Proteobacteria,42SNH@68525|delta/epsilon subdivisions,2WPQC@28221|Deltaproteobacteria,2MBCJ@213115|Desulfovibrionales	28221|Deltaproteobacteria	EJ	PFAM Asparaginase	aspG	-	3.5.1.1	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	-	R00485	RC00010,RC02798	ko00000,ko00001,ko01000	-	-	-	Asparaginase
k141_3243_2	485918.Cpin_5866	3.59e-20	90.5	COG4675@1|root,COG4675@2|Bacteria,4NQJR@976|Bacteroidetes,1IT97@117747|Sphingobacteriia	976|Bacteroidetes	S	Tail Collar domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Collar
k141_4275_1	796620.VIBC2010_12254	1.69e-77	238.0	291VY@1|root,2ZPFN@2|Bacteria,1P4BG@1224|Proteobacteria,1SUJ6@1236|Gammaproteobacteria,1XXNJ@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_5235_2	1250232.JQNJ01000001_gene1286	1.92e-70	226.0	COG0726@1|root,COG0726@2|Bacteria,4NQKC@976|Bacteroidetes,1I8X4@117743|Flavobacteriia	976|Bacteroidetes	G	polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_2273_1	99598.Cal7507_6126	8.56e-22	98.6	COG4191@1|root,COG4191@2|Bacteria,1G36N@1117|Cyanobacteria,1HQDX@1161|Nostocales	1117|Cyanobacteria	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
k141_2273_2	177437.HRM2_40240	6.69e-195	557.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,2MI07@213118|Desulfobacterales	28221|Deltaproteobacteria	T	PFAM response regulator receiver	-	-	-	ko:K02481,ko:K07712	ko02020,map02020	M00497	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
k141_2273_3	350058.Mvan_1818	1.43e-07	64.3	COG0574@1|root,COG3848@1|root,COG0574@2|Bacteria,COG3848@2|Bacteria,2GMN4@201174|Actinobacteria,23FDD@1762|Mycobacteriaceae	201174|Actinobacteria	G	PFAM pyruvate phosphate dikinase, PEP pyruvate-binding	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	Aminotran_3,PEP-utilizers,PPDK_N,Shikimate_DH
k141_844_1	345073.VC395_2453	6.4e-261	749.0	COG3250@1|root,COG3250@2|Bacteria,1MVBN@1224|Proteobacteria,1RMER@1236|Gammaproteobacteria,1XUKN@135623|Vibrionales	135623|Vibrionales	G	COG3250 Beta-galactosidase beta-glucuronidase	lacZ	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	Bgal_small_N,DUF4981,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
k141_844_2	1280001.BAOA01000034_gene2202	5.68e-243	677.0	COG2211@1|root,COG2211@2|Bacteria,1MVUM@1224|Proteobacteria,1RP5J@1236|Gammaproteobacteria,1XT0V@135623|Vibrionales	135623|Vibrionales	G	COG2211 Na melibiose symporter and related transporters	-	-	-	ko:K11104	-	-	-	-	ko00000,ko02000	2.A.2.1	-	-	MFS_2
k141_844_3	1440052.EAKF1_ch3254c	6.76e-43	145.0	COG1846@1|root,COG1846@2|Bacteria,1NM8R@1224|Proteobacteria,1S42F@1236|Gammaproteobacteria,3XQ62@561|Escherichia	1236|Gammaproteobacteria	K	transcriptional regulator	hosA	-	-	ko:K22489	-	-	-	-	ko00000,ko03000	-	-	-	MarR
k141_844_4	693444.D782_0693	1.82e-241	679.0	COG0747@1|root,COG0747@2|Bacteria,1P1HT@1224|Proteobacteria,1RQ7Z@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	nickel ABC transporter	nikA	GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006935,GO:0008150,GO:0009605,GO:0016151,GO:0020037,GO:0030288,GO:0030313,GO:0031975,GO:0040011,GO:0042221,GO:0042330,GO:0042597,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0046906,GO:0046914,GO:0048037,GO:0050896,GO:0050919,GO:0051540,GO:0097159,GO:1901363	-	ko:K02035,ko:K15584	ko02010,ko02024,map02010,map02024	M00239,M00440	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	iSFV_1184.SFV_3479	SBP_bac_5
k141_844_5	1121028.ARQE01000001_gene3185	1.81e-155	444.0	COG0601@1|root,COG0601@2|Bacteria,1MU8Z@1224|Proteobacteria,2TQKK@28211|Alphaproteobacteria,2PJ8E@255475|Aurantimonadaceae	28211|Alphaproteobacteria	U	Binding-protein-dependent transport system inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
k141_844_6	311402.Avi_7616	2e-113	335.0	COG1173@1|root,COG1173@2|Bacteria,1MW3R@1224|Proteobacteria,2TUCW@28211|Alphaproteobacteria,4B8XT@82115|Rhizobiaceae	28211|Alphaproteobacteria	EP	ABC-type dipeptide oligopeptide nickel transport systems, permease components	nikC	-	-	ko:K02034,ko:K15586	ko02010,ko02024,map02010,map02024	M00239,M00440	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
k141_844_7	224914.BMEII0490	1.15e-93	283.0	COG0444@1|root,COG0444@2|Bacteria,1R4F4@1224|Proteobacteria,2U1JY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	Part of the ABC transporter complex NikABCDE involved in nickel import. Responsible for energy coupling to the transport system	nikD	-	3.6.3.24	ko:K15587	ko02010,map02010	M00440	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.5	-	-	ABC_tran
k141_844_8	754331.AEME01000001_gene4102	5.82e-87	266.0	COG1124@1|root,COG1124@2|Bacteria,1R3X1@1224|Proteobacteria,1RMIC@1236|Gammaproteobacteria,3XM78@561|Escherichia	1236|Gammaproteobacteria	P	Part of the ABC transporter complex NikABCDE involved in nickel import. Responsible for energy coupling to the transport system	nikE	GO:0000041,GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0006810,GO:0006811,GO:0006812,GO:0006950,GO:0006974,GO:0008144,GO:0008150,GO:0009987,GO:0015675,GO:0017076,GO:0030001,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0034220,GO:0035444,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0055085,GO:0097159,GO:0097367,GO:0098655,GO:0098660,GO:0098662,GO:1901265,GO:1901363	3.6.3.24	ko:K10824	ko02010,map02010	M00440	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.5	-	iAPECO1_1312.APECO1_2974,iE2348C_1286.E2348C_3721,iECABU_c1320.ECABU_c39100,iECED1_1282.ECED1_4153,iECOK1_1307.ECOK1_3909,iECP_1309.ECP_3575,iECS88_1305.ECS88_3883,iUMN146_1321.UM146_17525,iUTI89_1310.UTI89_C3997,ic_1306.c4273	ABC_tran
k141_844_9	701347.Entcl_2626	7.02e-46	152.0	COG0864@1|root,COG0864@2|Bacteria,1RK4R@1224|Proteobacteria,1S44Q@1236|Gammaproteobacteria,3X2GR@547|Enterobacter	1236|Gammaproteobacteria	K	Transcriptional repressor of the nikABCDE operon. Is active in the presence of excessive concentrations of intracellular nickel	nikR	GO:0000976,GO:0000984,GO:0000985,GO:0001017,GO:0001046,GO:0001047,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016043,GO:0016151,GO:0019219,GO:0019222,GO:0022607,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0032991,GO:0032993,GO:0042802,GO:0043167,GO:0043169,GO:0043254,GO:0043565,GO:0043933,GO:0044085,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0060255,GO:0065003,GO:0065007,GO:0071840,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141	-	ko:K07722	-	-	-	-	ko00000,ko03000	-	-	-	NikR_C,RHH_1
k141_844_10	1348635.BBJY01000004_gene2891	4.72e-208	602.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,1XTM0@135623|Vibrionales	135623|Vibrionales	NT	methyl-accepting chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,CHASE3,HBM,MCPsignal
k141_844_11	1219076.N646_0516	8.11e-282	781.0	COG1292@1|root,COG1292@2|Bacteria,1MV0K@1224|Proteobacteria,1RP3E@1236|Gammaproteobacteria,1XTJH@135623|Vibrionales	135623|Vibrionales	M	Belongs to the BCCT transporter (TC 2.A.15) family	-	-	-	ko:K03451	-	-	-	-	ko00000	2.A.15	-	-	BCCT
k141_844_12	1322246.BN4_10163	1.51e-25	108.0	COG1418@1|root,COG1418@2|Bacteria,1MYFV@1224|Proteobacteria,42SP6@68525|delta/epsilon subdivisions,2WP9Z@28221|Deltaproteobacteria,2MBXN@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	PFAM Metal-dependent phosphohydrolase, HD	-	-	-	-	-	-	-	-	-	-	-	-	HD
k141_844_14	1219065.VPR01S_04_02250	1.63e-198	573.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMV2@1236|Gammaproteobacteria,1XSAN@135623|Vibrionales	135623|Vibrionales	T	methyl-accepting chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal,sCache_2
k141_2846_1	1051646.VITU9109_14733	6.78e-20	87.4	29XW5@1|root,30JNI@2|Bacteria,1QKDG@1224|Proteobacteria,1TIH6@1236|Gammaproteobacteria,1XZ48@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_2846_2	1214065.BAGV01000039_gene446	1.06e-140	404.0	COG0560@1|root,COG0560@2|Bacteria,1R6HK@1224|Proteobacteria,1S00M@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD
k141_2846_4	243277.VC_A0323	1.1e-53	169.0	COG3041@1|root,COG3041@2|Bacteria,1N0K0@1224|Proteobacteria,1SFP9@1236|Gammaproteobacteria,1XYK6@135623|Vibrionales	135623|Vibrionales	S	Bacterial toxin of type II toxin-antitoxin system, YafQ	-	-	-	ko:K19157	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	YafQ_toxin
k141_2846_5	29495.EA26_14575	4.94e-50	160.0	COG3077@1|root,COG3077@2|Bacteria,1N4SN@1224|Proteobacteria,1SAH7@1236|Gammaproteobacteria,1XYKT@135623|Vibrionales	135623|Vibrionales	L	RelB antitoxin	-	-	-	ko:K07473	-	-	-	-	ko00000,ko02048	-	-	-	RelB
k141_5236_1	1238450.VIBNISOn1_960029	1.97e-80	247.0	COG2837@1|root,COG2837@2|Bacteria,1MWDD@1224|Proteobacteria,1RMZJ@1236|Gammaproteobacteria,1XU5E@135623|Vibrionales	135623|Vibrionales	P	iron-dependent peroxidase	-	-	-	ko:K07223	-	-	-	-	ko00000	-	-	-	Dyp_perox
k141_2274_1	332101.JIBU02000057_gene2649	2.13e-08	57.8	COG2186@1|root,COG2186@2|Bacteria,1V2TU@1239|Firmicutes,24GA8@186801|Clostridia,36F6A@31979|Clostridiaceae	186801|Clostridia	K	GntR domain protein	-	-	-	ko:K05799	-	-	-	-	ko00000,ko03000	-	-	-	FCD,GntR
k141_2275_1	1232437.KL662033_gene2671	9.66e-68	219.0	COG0277@1|root,COG0277@2|Bacteria,1MU6Y@1224|Proteobacteria,42M0V@68525|delta/epsilon subdivisions,2WIQ1@28221|Deltaproteobacteria,2MI3F@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM FAD linked oxidase domain protein	larD	-	1.1.3.15	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001,ko01000	-	-	iAF987.Gmet_3245	FAD-oxidase_C,FAD_binding_4
k141_4276_1	96561.Dole_2735	1.48e-168	492.0	COG0606@1|root,COG0606@2|Bacteria,1MU4R@1224|Proteobacteria,42NBJ@68525|delta/epsilon subdivisions,2WJ52@28221|Deltaproteobacteria,2MHQI@213118|Desulfobacterales	28221|Deltaproteobacteria	O	chelatase, subunit ChlI	comM	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
k141_3649_1	1382358.JHVN01000005_gene3039	1.66e-92	288.0	COG3829@1|root,COG3829@2|Bacteria,1TP0E@1239|Firmicutes,4HADT@91061|Bacilli,21VFX@150247|Anoxybacillus	91061|Bacilli	KT	Sigma-54 interaction domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,PAS,PAS_9,Sigma54_activat
k141_5237_1	439235.Dalk_1572	2.14e-120	352.0	COG1028@1|root,COG1028@2|Bacteria,1R7KW@1224|Proteobacteria,42NF5@68525|delta/epsilon subdivisions,2WM4D@28221|Deltaproteobacteria,2MIF5@213118|Desulfobacterales	28221|Deltaproteobacteria	IQ	PFAM short-chain dehydrogenase reductase SDR	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
k141_3945_2	476272.RUMHYD_03630	3.12e-81	248.0	COG0378@1|root,COG0378@2|Bacteria,1TS00@1239|Firmicutes,248T1@186801|Clostridia,3XZ4U@572511|Blautia	186801|Clostridia	KO	UreA amidohydrolase (urease) regulatory and maturation protein UreG	hypB	-	-	ko:K04652	-	-	-	-	ko00000,ko03110	-	-	-	cobW
k141_3945_3	1304885.AUEY01000095_gene2619	7.86e-28	105.0	COG0375@1|root,COG0375@2|Bacteria,1Q8XY@1224|Proteobacteria,43EVY@68525|delta/epsilon subdivisions,2WTED@28221|Deltaproteobacteria,2MP81@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Hydrogenase/urease nickel incorporation, metallochaperone, hypA	-	-	-	-	-	-	-	-	-	-	-	-	HypA
k141_3945_4	933262.AXAM01000038_gene911	1.83e-71	233.0	COG1243@1|root,COG1243@2|Bacteria,1MUYS@1224|Proteobacteria,42N2I@68525|delta/epsilon subdivisions,2WKZX@28221|Deltaproteobacteria,2MINY@213118|Desulfobacterales	28221|Deltaproteobacteria	BK	PFAM Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM,Radical_SAM_C
k141_3945_5	1304885.AUEY01000016_gene3056	1.79e-69	220.0	COG0571@1|root,COG0571@2|Bacteria,1MUQ6@1224|Proteobacteria,42MIP@68525|delta/epsilon subdivisions,2WNDB@28221|Deltaproteobacteria,2MJYR@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism	rnc	GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	-	-	-	Ribonucleas_3_3,dsrm
k141_3945_6	1232437.KL661988_gene113	2.78e-71	234.0	COG0571@1|root,COG0613@1|root,COG0571@2|Bacteria,COG0613@2|Bacteria,1MUQ6@1224|Proteobacteria,42MIP@68525|delta/epsilon subdivisions,2X73H@28221|Deltaproteobacteria,2MII1@213118|Desulfobacterales	28221|Deltaproteobacteria	K	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism	rnc	-	3.1.26.3,3.1.3.97	ko:K03685,ko:K07053	ko03008,ko05205,map03008,map05205	-	R00188,R11188	RC00078	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	-	-	-	PHP,Ribonucleas_3_3,dsrm
k141_3945_7	1121405.dsmv_1732	4.19e-57	179.0	COG1734@1|root,COG1734@2|Bacteria,1RD08@1224|Proteobacteria,42RVK@68525|delta/epsilon subdivisions,2WNNA@28221|Deltaproteobacteria,2MJSM@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters	dksA	-	-	ko:K06204	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000,ko03009,ko03021	-	-	-	zf-dskA_traR
k141_3945_8	1121405.dsmv_1721	1.38e-85	270.0	COG0373@1|root,COG0373@2|Bacteria,1MU41@1224|Proteobacteria,42MUG@68525|delta/epsilon subdivisions,2WISB@28221|Deltaproteobacteria,2MIIU@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,GlutR_dimer,Shikimate_DH
k141_3946_1	177437.HRM2_45360	2.37e-48	172.0	COG0642@1|root,COG5000@1|root,COG2205@2|Bacteria,COG5000@2|Bacteria,1N9SU@1224|Proteobacteria,42UBN@68525|delta/epsilon subdivisions,2WQMC@28221|Deltaproteobacteria,2MKK0@213118|Desulfobacterales	28221|Deltaproteobacteria	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	2.7.13.3	ko:K07640	ko01503,ko02020,map01503,map02020	M00447,M00727,M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
k141_2277_1	177437.HRM2_47180	4.53e-76	257.0	COG0210@1|root,COG0514@1|root,COG0210@2|Bacteria,COG0514@2|Bacteria,1MVGG@1224|Proteobacteria,42MV3@68525|delta/epsilon subdivisions,2WJZB@28221|Deltaproteobacteria,2MHKM@213118|Desulfobacterales	28221|Deltaproteobacteria	L	TIGRFAM ATP-dependent DNA helicase, RecQ	-	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,HRDC,HTH_40,Helicase_C,RQC,RecQ_Zn_bind,UvrD-helicase,UvrD_C
k141_845_1	232346.JHQL01000001_gene2205	2.72e-64	209.0	COG4608@1|root,COG4608@2|Bacteria,1NU4K@1224|Proteobacteria,1SKPD@1236|Gammaproteobacteria,1XHT4@135619|Oceanospirillales	135619|Oceanospirillales	P	Belongs to the ABC transporter superfamily	dppF	-	-	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
k141_845_2	1208321.D104_03025	6.5e-158	452.0	COG0444@1|root,COG0444@2|Bacteria,1R4KB@1224|Proteobacteria,1SMBI@1236|Gammaproteobacteria,1XHHK@135619|Oceanospirillales	135619|Oceanospirillales	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K02031	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
k141_845_3	717774.Marme_2864	1.57e-139	404.0	COG1173@1|root,COG1173@2|Bacteria,1MUG0@1224|Proteobacteria,1RN08@1236|Gammaproteobacteria,1XHIT@135619|Oceanospirillales	135619|Oceanospirillales	EP	(ABC) transporter, permease	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
k141_845_4	1208321.D104_03035	6.41e-68	214.0	COG0601@1|root,COG0601@2|Bacteria,1MU8Z@1224|Proteobacteria,1RNJ1@1236|Gammaproteobacteria,1XIV4@135619|Oceanospirillales	135619|Oceanospirillales	P	(ABC) transporter, permease	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
k141_599_1	929558.SMGD1_2545	9.18e-202	602.0	COG2319@1|root,COG4249@1|root,COG2319@2|Bacteria,COG4249@2|Bacteria,1NJ33@1224|Proteobacteria,42PEW@68525|delta/epsilon subdivisions	1224|Proteobacteria	T	Peptidase C14, caspase catalytic	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C14,TIR_2,WD40
k141_3651_1	1232437.KL662001_gene4653	1.22e-08	55.5	COG0854@1|root,COG0854@2|Bacteria,1MU9W@1224|Proteobacteria,42NZY@68525|delta/epsilon subdivisions,2WJDY@28221|Deltaproteobacteria,2MJ54@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate	pdxJ	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	2.6.99.2	ko:K03474	ko00750,ko01100,map00750,map01100	M00124	R05838	RC01476	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1885	PdxJ
k141_3651_2	1232437.KL662001_gene4587	1.53e-93	298.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,1MU1Q@1224|Proteobacteria,42ND6@68525|delta/epsilon subdivisions,2WIJS@28221|Deltaproteobacteria,2MHY5@213118|Desulfobacterales	28221|Deltaproteobacteria	G	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	Carb_kinase,YjeF_N
k141_5239_1	1454202.PPBDW_130257___1	4.77e-62	205.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,1RMWA@1236|Gammaproteobacteria,1XTY4@135623|Vibrionales	135623|Vibrionales	JKL	Belongs to the DEAD box helicase family	-	-	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
k141_5239_2	1051646.VITU9109_01927	1.27e-72	229.0	COG1309@1|root,COG1309@2|Bacteria,1R9P8@1224|Proteobacteria,1SZ5B@1236|Gammaproteobacteria,1Y26D@135623|Vibrionales	135623|Vibrionales	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
k141_5239_3	617140.AJZE01000105_gene361	9.64e-68	211.0	COG0494@1|root,COG0494@2|Bacteria,1RCX7@1224|Proteobacteria,1RSM2@1236|Gammaproteobacteria,1XX52@135623|Vibrionales	135623|Vibrionales	L	COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes	-	-	3.6.1.13	ko:K01515	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
k141_3948_2	1536775.H70737_07345	8.45e-17	77.0	COG0607@1|root,COG0607@2|Bacteria,1VAI7@1239|Firmicutes,4HKCE@91061|Bacilli,274UW@186822|Paenibacillaceae	91061|Bacilli	P	Rhodanese Homology Domain	yqhL	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
k141_3948_3	644282.Deba_2066	2.68e-56	177.0	COG5561@1|root,COG5561@2|Bacteria,1RH81@1224|Proteobacteria,42SY4@68525|delta/epsilon subdivisions,2WPAG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	CGGC	-	-	-	-	-	-	-	-	-	-	-	-	CGGC
k141_3244_1	1188252.AJYK01000110_gene2438	1.5e-90	283.0	COG2801@1|root,COG2801@2|Bacteria,1MXCK@1224|Proteobacteria,1RV69@1236|Gammaproteobacteria,1XWAP@135623|Vibrionales	135623|Vibrionales	L	Integrase core domain	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	Mu-transpos_C,rve
k141_3244_2	1188252.AJYK01000110_gene2437	2.6e-76	235.0	2BVEU@1|root,32QUD@2|Bacteria,1RJ4J@1224|Proteobacteria,1S5X1@1236|Gammaproteobacteria,1XYDC@135623|Vibrionales	135623|Vibrionales	S	TnsA endonuclease N terminal	-	-	-	-	-	-	-	-	-	-	-	-	Tn7_Tnp_TnsA_N
k141_3244_3	55601.VANGNB10_cI1794c	4.32e-191	556.0	COG0834@1|root,COG2199@1|root,COG0834@2|Bacteria,COG2199@2|Bacteria,1NS3W@1224|Proteobacteria,1SKY3@1236|Gammaproteobacteria,1XSPX@135623|Vibrionales	135623|Vibrionales	ET	Bacterial extracellular solute-binding proteins, family 3	-	-	2.7.7.65	ko:K20957	ko05111,map05111	-	-	-	ko00000,ko00001,ko01000	-	-	-	GGDEF,SBP_bac_3
k141_600_1	998674.ATTE01000001_gene583	1.86e-41	138.0	COG0760@1|root,COG0760@2|Bacteria,1MZDK@1224|Proteobacteria,1S9DN@1236|Gammaproteobacteria,460WU@72273|Thiotrichales	72273|Thiotrichales	G	Peptidylprolyl isomerase	ppiC	-	5.2.1.8	ko:K03769	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_3
k141_600_2	235985.BBPN01000011_gene4219	1.1e-17	87.4	COG2267@1|root,COG2267@2|Bacteria,2GISG@201174|Actinobacteria,2NGG4@228398|Streptacidiphilus	201174|Actinobacteria	I	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
k141_4278_1	933262.AXAM01000090_gene2618	7.73e-11	72.4	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42PQS@68525|delta/epsilon subdivisions,2WKTB@28221|Deltaproteobacteria,2MJ0D@213118|Desulfobacterales	28221|Deltaproteobacteria	NT	Type IV pili methyl-accepting chemotaxis transducer N-term	-	-	-	-	-	-	-	-	-	-	-	-	MCPsignal,PilJ
k141_602_1	1121440.AUMA01000012_gene1384	1.11e-40	142.0	COG0500@1|root,COG2226@2|Bacteria,1RBQY@1224|Proteobacteria,43004@68525|delta/epsilon subdivisions,2WVHG@28221|Deltaproteobacteria,2MBE2@213115|Desulfovibrionales	28221|Deltaproteobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
k141_3245_1	1249480.B649_01945	2.57e-20	97.1	COG2199@1|root,COG2202@1|root,COG3829@1|root,COG2202@2|Bacteria,COG3706@2|Bacteria,COG3829@2|Bacteria,1RAQ1@1224|Proteobacteria,42ZAX@68525|delta/epsilon subdivisions,2YR5R@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	KT	PAS fold	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS_9
k141_5240_1	1121405.dsmv_2188	6.18e-167	474.0	COG0113@1|root,COG0113@2|Bacteria,1MWMW@1224|Proteobacteria,42N17@68525|delta/epsilon subdivisions,2WJE8@28221|Deltaproteobacteria,2MI2X@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Belongs to the ALAD family	hemB	-	4.2.1.24	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00036	RC00918,RC01781	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ALAD
k141_5240_2	879212.DespoDRAFT_01087	4.05e-30	116.0	COG0535@1|root,COG0535@2|Bacteria,1MUQP@1224|Proteobacteria,42M55@68525|delta/epsilon subdivisions,2WIKM@28221|Deltaproteobacteria,2MJ60@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM Radical SAM domain protein	-	-	-	ko:K22227	-	-	-	-	ko00000	-	-	-	Fer4_12,Fer4_14,Radical_SAM,SPASM
k141_847_1	1304885.AUEY01000013_gene3091	2.18e-85	263.0	COG1660@1|root,COG1660@2|Bacteria,1MVX6@1224|Proteobacteria,42MZM@68525|delta/epsilon subdivisions,2WJG6@28221|Deltaproteobacteria,2MJ01@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Displays ATPase and GTPase activities	-	-	-	ko:K06958	-	-	-	-	ko00000,ko03019	-	-	-	ATP_bind_2
k141_847_2	1304885.AUEY01000013_gene3092	4.74e-49	161.0	COG2893@1|root,COG2893@2|Bacteria,1RHH7@1224|Proteobacteria,42SST@68525|delta/epsilon subdivisions,2WPWN@28221|Deltaproteobacteria,2MK4F@213118|Desulfobacterales	28221|Deltaproteobacteria	G	PFAM PTS system fructose subfamily IIA component	-	-	2.7.1.191	ko:K02793	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	M00276	R02630	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.6.1	-	-	EIIA-man
k141_5244_12	1248232.BANQ01000075_gene1573	3.09e-91	275.0	COG0744@1|root,COG0744@2|Bacteria,1RDAQ@1224|Proteobacteria,1RMGB@1236|Gammaproteobacteria,1XWFV@135623|Vibrionales	135623|Vibrionales	M	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors	mtgA	-	2.4.1.129	ko:K03814	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly
k141_5244_14	1283284.AZUK01000001_gene2456	3.76e-93	275.0	COG0634@1|root,COG0634@2|Bacteria	2|Bacteria	F	Belongs to the purine pyrimidine phosphoribosyltransferase family	hpt	-	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
k141_5244_15	1051646.VITU9109_24455	2.42e-95	283.0	COG2176@1|root,COG2176@2|Bacteria,1QUHH@1224|Proteobacteria,1T1Z7@1236|Gammaproteobacteria,1XUWD@135623|Vibrionales	135623|Vibrionales	L	COG2176 DNA polymerase III, alpha subunit (gram-positive type)	-	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	RNase_T
k141_5244_16	319224.Sputcn32_0349	4.12e-77	238.0	COG4565@1|root,COG4565@2|Bacteria,1P6VJ@1224|Proteobacteria,1RPI7@1236|Gammaproteobacteria,2QCN7@267890|Shewanellaceae	1236|Gammaproteobacteria	K	cheY-homologous receiver domain	dpiA	GO:0000156,GO:0000160,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0007154,GO:0007165,GO:0008150,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0023052,GO:0031323,GO:0031326,GO:0035556,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0051716,GO:0060089,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141	-	ko:K02475,ko:K07702	ko02020,map02020	M00486	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	CitT,Response_reg
k141_5244_17	675813.VIB_001187	2.77e-193	558.0	COG3290@1|root,COG3290@2|Bacteria,1MXQ5@1224|Proteobacteria,1RNRF@1236|Gammaproteobacteria,1XSAU@135623|Vibrionales	1236|Gammaproteobacteria	T	COG3290 Signal transduction histidine kinase regulating citrate malate metabolism	dcuS	GO:0000155,GO:0000160,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006355,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0016020,GO:0016021,GO:0016043,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0018106,GO:0018193,GO:0018202,GO:0019219,GO:0019222,GO:0019538,GO:0022607,GO:0023014,GO:0023052,GO:0031224,GO:0031226,GO:0031323,GO:0031326,GO:0035556,GO:0036211,GO:0042802,GO:0043170,GO:0043412,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0051259,GO:0051260,GO:0051716,GO:0060255,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:0071944,GO:0080090,GO:0140096,GO:1901564,GO:1903506,GO:2000112,GO:2001141	2.7.13.3	ko:K02476,ko:K07701,ko:K11614	ko02020,map02020	M00488,M00490	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,PAS,SPOB_a,sCache_3_2
k141_5244_18	1051646.VITU9109_02407	2.58e-242	674.0	COG2704@1|root,COG2704@2|Bacteria,1MVHH@1224|Proteobacteria,1RPTE@1236|Gammaproteobacteria,1XT7X@135623|Vibrionales	135623|Vibrionales	S	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane	-	-	-	ko:K07792	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.13.1	-	-	DcuA_DcuB
k141_5244_19	1120970.AUBZ01000057_gene1787	6.91e-56	181.0	COG2110@1|root,COG2110@2|Bacteria,1RCWP@1224|Proteobacteria,1S3WJ@1236|Gammaproteobacteria,468H4@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Appr-1'-p processing enzyme	ymdB	GO:0003674,GO:0003824,GO:0004857,GO:0005488,GO:0005515,GO:0008150,GO:0008428,GO:0009892,GO:0010605,GO:0016787,GO:0019213,GO:0019219,GO:0019222,GO:0019899,GO:0030234,GO:0031323,GO:0031324,GO:0032069,GO:0032074,GO:0043086,GO:0043900,GO:0044092,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051336,GO:0051346,GO:0060255,GO:0060698,GO:0060699,GO:0060700,GO:0060701,GO:0060702,GO:0061463,GO:0065007,GO:0065009,GO:0080090,GO:0098772,GO:1900190,GO:1900231	-	-	-	-	-	-	-	-	-	-	Macro
k141_5244_20	1082705.JIBP01000017_gene744	2.63e-62	218.0	COG4943@1|root,COG4943@2|Bacteria,1MVTH@1224|Proteobacteria,1RMDP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	signal transduction protein containing sensor and EAL	yjcC	-	-	-	-	-	-	-	-	-	-	-	CSS-motif,EAL
k141_5244_21	1348635.BBJY01000004_gene2911	2.14e-154	448.0	COG0477@1|root,COG2814@2|Bacteria,1MU9G@1224|Proteobacteria,1RM9G@1236|Gammaproteobacteria,1XV9G@135623|Vibrionales	135623|Vibrionales	EGP	Major Facilitator Superfamily	-	-	-	ko:K08159	-	-	-	-	ko00000,ko02000	2.A.1.2.15,2.A.1.2.18	-	-	MFS_1
k141_5244_22	1274524.BSONL12_06813	7.33e-265	735.0	COG2723@1|root,COG2723@2|Bacteria,1TP19@1239|Firmicutes,4HA1W@91061|Bacilli,1ZEK4@1386|Bacillus	91061|Bacilli	G	Belongs to the glycosyl hydrolase 1 family	-	-	3.2.1.86	ko:K01223	ko00010,ko00500,map00010,map00500	-	R00839,R05133,R05134	RC00049,RC00171,RC00714	ko00000,ko00001,ko01000	-	GT1	-	Glyco_hydro_1
k141_3321_6	439235.Dalk_0302	2.15e-73	226.0	COG1100@1|root,COG1100@2|Bacteria,1RCJJ@1224|Proteobacteria,42R57@68525|delta/epsilon subdivisions,2WN5Y@28221|Deltaproteobacteria,2MMIS@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Small GTP-binding protein	-	-	-	ko:K06883	-	-	-	-	ko00000	-	-	-	Arf
k141_3024_1	1265505.ATUG01000002_gene2790	2.42e-22	93.6	29HYV@1|root,304VW@2|Bacteria,1RDPY@1224|Proteobacteria,42RXW@68525|delta/epsilon subdivisions,2WNTT@28221|Deltaproteobacteria,2MJZ3@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_3024_2	502025.Hoch_4588	6.71e-14	68.9	COG2331@1|root,COG2331@2|Bacteria,1N6Q9@1224|Proteobacteria,42V24@68525|delta/epsilon subdivisions,2WR87@28221|Deltaproteobacteria,2YW0Y@29|Myxococcales	28221|Deltaproteobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
k141_3024_3	1304885.AUEY01000054_gene162	6.55e-45	147.0	COG0234@1|root,COG0234@2|Bacteria,1MZ2X@1224|Proteobacteria,42U7E@68525|delta/epsilon subdivisions,2WPZP@28221|Deltaproteobacteria,2MKH2@213118|Desulfobacterales	28221|Deltaproteobacteria	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
k141_3024_4	879212.DespoDRAFT_02707	3.33e-94	291.0	COG0459@1|root,COG0459@2|Bacteria,1MURR@1224|Proteobacteria,42M52@68525|delta/epsilon subdivisions,2WIRK@28221|Deltaproteobacteria,2MHPV@213118|Desulfobacterales	28221|Deltaproteobacteria	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	-	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
k141_1688_4	104623.Ser39006_00725	8.93e-45	156.0	COG3550@1|root,COG3550@2|Bacteria,1N458@1224|Proteobacteria,1RMP7@1236|Gammaproteobacteria,403T5@613|Serratia	1236|Gammaproteobacteria	S	Pfam:HipA_N	hipA	-	2.7.11.1	ko:K07154	-	-	-	-	ko00000,ko01000,ko01001,ko02048	-	-	-	Couple_hipA,HipA_C
k141_1689_1	1454004.AW11_01268	2.33e-18	90.1	COG0443@1|root,COG0443@2|Bacteria,1MXX7@1224|Proteobacteria,2VH7D@28216|Betaproteobacteria	28216|Betaproteobacteria	O	Belongs to the heat shock protein 70 family	-	-	-	-	-	-	-	-	-	-	-	-	DUF3731,HSP70
k141_1689_2	485915.Dret_0166	3.11e-100	296.0	COG4117@1|root,COG4117@2|Bacteria,1R5GN@1224|Proteobacteria,42QVP@68525|delta/epsilon subdivisions,2WMT7@28221|Deltaproteobacteria,2M7S8@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	Prokaryotic cytochrome b561	cbcB	-	-	-	-	-	-	-	-	-	-	-	Ni_hydr_CYTB
k141_1689_3	1121406.JAEX01000003_gene1687	1.02e-148	438.0	28I8B@1|root,2Z8B5@2|Bacteria,1MUNM@1224|Proteobacteria,42NZH@68525|delta/epsilon subdivisions,2WKHB@28221|Deltaproteobacteria,2M9ZJ@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	Cytochrome c bacterial	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554,Cytochrome_C7,Cytochrome_cB
k141_3370_2	177437.HRM2_24840	1.21e-69	220.0	COG1076@1|root,COG1076@2|Bacteria,1N270@1224|Proteobacteria,42STV@68525|delta/epsilon subdivisions,2WKKA@28221|Deltaproteobacteria,2MJB6@213118|Desulfobacterales	28221|Deltaproteobacteria	O	Tellurite resistance protein TerB	-	-	-	ko:K05801	-	-	-	-	ko00000,ko03110	-	-	-	DnaJ,TerB
k141_4415_1	998674.ATTE01000001_gene3099	2.6e-39	137.0	COG1611@1|root,COG1611@2|Bacteria,1RD59@1224|Proteobacteria,1S4C3@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Belongs to the LOG family	yvdD	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
k141_4415_2	36331.EPrPI00000015918	8.64e-46	166.0	KOG2524@1|root,KOG2524@2759|Eukaryota,1MB2T@121069|Pythiales	121069|Pythiales	H	Cytoplasmic protein of eukaryotic origin (38.3 kD). Source PGD	-	-	-	-	-	-	-	-	-	-	-	-	Q_salvage
k141_4415_3	883.DvMF_1868	3.28e-188	550.0	COG0247@1|root,COG1139@1|root,COG0247@2|Bacteria,COG1139@2|Bacteria,1MV6J@1224|Proteobacteria,42MN2@68525|delta/epsilon subdivisions,2WIMJ@28221|Deltaproteobacteria,2M99N@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	LUD domain	-	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_7,Fer4_8,LUD_dom
k141_4416_1	177437.HRM2_45690	1.48e-116	345.0	COG0731@1|root,COG0731@2|Bacteria,1QG36@1224|Proteobacteria,42M82@68525|delta/epsilon subdivisions,2WKGK@28221|Deltaproteobacteria,2MHYQ@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_14,Radical_SAM
k141_4417_2	177437.HRM2_17530	2.94e-223	627.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,42MK5@68525|delta/epsilon subdivisions,2WJ3Z@28221|Deltaproteobacteria,2MHKF@213118|Desulfobacterales	28221|Deltaproteobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
k141_4418_1	398578.Daci_5514	1.24e-51	195.0	COG2373@1|root,COG4733@1|root,COG4932@1|root,COG5272@1|root,COG2373@2|Bacteria,COG4733@2|Bacteria,COG4932@2|Bacteria,COG5272@2|Bacteria	2|Bacteria	O	ubiquitin	-	-	-	ko:K02927,ko:K07451,ko:K13735	ko03010,ko05100,map03010,map05100	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko01000,ko02048,ko03011	-	-	-	Phage-tail_3,SLH,SdrD_B,fn3,ubiquitin
k141_4419_1	489825.LYNGBM3L_49280	2.1e-23	100.0	COG1012@1|root,COG1012@2|Bacteria,1G2U1@1117|Cyanobacteria,1H7XG@1150|Oscillatoriales	1117|Cyanobacteria	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.3	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
k141_4419_2	7897.ENSLACP00000009389	1.08e-16	79.7	COG1012@1|root,KOG2456@2759|Eukaryota,38CW8@33154|Opisthokonta,3BDR1@33208|Metazoa,3CZ4X@33213|Bilateria	33208|Metazoa	C	Belongs to the aldehyde dehydrogenase family	ALDH3B1	GO:0001775,GO:0002252,GO:0002263,GO:0002274,GO:0002275,GO:0002283,GO:0002366,GO:0002376,GO:0002443,GO:0002444,GO:0002446,GO:0003674,GO:0003824,GO:0004028,GO:0004029,GO:0004030,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005811,GO:0005829,GO:0005886,GO:0006066,GO:0006081,GO:0006629,GO:0006643,GO:0006665,GO:0006807,GO:0006810,GO:0006887,GO:0006950,GO:0006955,GO:0006979,GO:0008150,GO:0008152,GO:0008610,GO:0009056,GO:0009058,GO:0009987,GO:0012505,GO:0012506,GO:0016020,GO:0016192,GO:0016491,GO:0016620,GO:0016903,GO:0030141,GO:0030148,GO:0030659,GO:0030667,GO:0031090,GO:0031410,GO:0031982,GO:0032940,GO:0033554,GO:0034599,GO:0035579,GO:0036230,GO:0042119,GO:0042221,GO:0042581,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043232,GO:0043299,GO:0043312,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044255,GO:0044281,GO:0044422,GO:0044424,GO:0044433,GO:0044444,GO:0044446,GO:0044464,GO:0045055,GO:0045321,GO:0046185,GO:0046467,GO:0046903,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0055114,GO:0070887,GO:0071704,GO:0071944,GO:0097708,GO:0098588,GO:0098805,GO:0099503,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615	1.2.1.3,1.2.1.5	ko:K00128,ko:K00129,ko:K04513	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00350,ko00360,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00980,ko00981,ko00982,ko01100,ko01110,ko01120,ko01130,ko04011,ko04014,ko04015,ko04022,ko04024,ko04062,ko04071,ko04072,ko04144,ko04150,ko04270,ko04310,ko04350,ko04360,ko04510,ko04520,ko04530,ko04611,ko04621,ko04660,ko04670,ko04722,ko04810,ko04921,ko04972,ko05100,ko05130,ko05133,ko05152,ko05200,ko05203,ko05204,ko05205,ko05206,ko05210,ko05418,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00350,map00360,map00380,map00410,map00561,map00620,map00625,map00903,map00980,map00981,map00982,map01100,map01110,map01120,map01130,map04011,map04014,map04015,map04022,map04024,map04062,map04071,map04072,map04144,map04150,map04270,map04310,map04350,map04360,map04510,map04520,map04530,map04611,map04621,map04660,map04670,map04722,map04810,map04921,map04972,map05100,map05130,map05133,map05152,map05200,map05203,map05204,map05205,map05206,map05210,map05418	M00135	R00264,R00631,R00710,R00711,R00904,R01752,R01986,R02536,R02537,R02549,R02678,R02695,R02697,R02940,R02957,R03283,R03300,R03302,R03869,R04065,R04506,R04882,R04883,R04888,R04889,R04891,R04892,R04903,R04996,R05050,R05237,R05238,R05286,R06366,R07104,R08146,R08282,R08283,R08307	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500,RC01735	ko00000,ko00001,ko00002,ko01000,ko04031,ko04131,ko04147	-	-	-	Aldedh
k141_3372_3	1304885.AUEY01000019_gene1153	0.0	1157.0	COG0495@1|root,COG0495@2|Bacteria,1MV47@1224|Proteobacteria,42MRQ@68525|delta/epsilon subdivisions,2WJ3E@28221|Deltaproteobacteria,2MJ6A@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	iAF987.Gmet_2300	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
k141_4420_1	1233950.IW22_16735	1.54e-81	268.0	COG0846@1|root,COG1431@1|root,COG0846@2|Bacteria,COG1431@2|Bacteria,4NH01@976|Bacteroidetes,1HXIT@117743|Flavobacteriia,3ZU2E@59732|Chryseobacterium	976|Bacteroidetes	J	Piwi	-	-	-	-	-	-	-	-	-	-	-	-	SIR2_2
k141_4421_1	425104.Ssed_2865	2.93e-34	135.0	COG0642@1|root,COG0834@1|root,COG5002@1|root,COG0642@2|Bacteria,COG0834@2|Bacteria,COG2205@2|Bacteria,COG5002@2|Bacteria,1NRP8@1224|Proteobacteria,1SKTW@1236|Gammaproteobacteria,2QACP@267890|Shewanellaceae	1236|Gammaproteobacteria	T	histidine kinase A domain protein	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	CHASE,GAF_2,HAMP,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg,SBP_bac_3,dCache_1
k141_5369_2	55601.VANGNB10_cI2096c	1.14e-196	553.0	COG2821@1|root,COG2821@2|Bacteria,1MXD4@1224|Proteobacteria,1RP7K@1236|Gammaproteobacteria,1XTDJ@135623|Vibrionales	135623|Vibrionales	M	membrane-bound lytic murein transglycosylase	mltA	GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009253,GO:0030203,GO:0043170,GO:0071704,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575	-	ko:K08304	-	-	-	-	ko00000,ko01000,ko01011	-	GH102	-	3D,MltA
k141_5369_3	29495.EA26_17630	5.32e-174	487.0	COG1179@1|root,COG1179@2|Bacteria,1MWXR@1224|Proteobacteria,1RMT3@1236|Gammaproteobacteria,1XSUQ@135623|Vibrionales	135623|Vibrionales	H	COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1	ygdL	-	-	ko:K22132	-	-	-	-	ko00000,ko03016	-	-	-	ThiF
k141_5369_4	1219077.VAZ01S_010_00810	1e-55	178.0	COG2166@1|root,COG2166@2|Bacteria,1RI8F@1224|Proteobacteria,1S65C@1236|Gammaproteobacteria,1XX28@135623|Vibrionales	135623|Vibrionales	S	COG2166 SufE protein probably involved in Fe-S center assembly	csdE	-	-	ko:K02426	-	-	-	-	ko00000	-	-	-	SufE
k141_5369_5	345073.VC395_2425	2.68e-189	537.0	COG0520@1|root,COG0520@2|Bacteria,1MUPD@1224|Proteobacteria,1RNIY@1236|Gammaproteobacteria,1XTR5@135623|Vibrionales	135623|Vibrionales	E	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine	csdA	GO:0003674,GO:0003824,GO:0008483,GO:0016740,GO:0016769	2.8.1.7,4.4.1.16	ko:K01766,ko:K11717	ko00450,ko01100,map00450,map01100	-	R03599,R11528	RC00961,RC01789,RC02313	ko00000,ko00001,ko01000	-	-	-	Aminotran_5
k141_5369_6	1280001.BAOA01000081_gene2935	2.09e-102	300.0	COG0693@1|root,COG0693@2|Bacteria,1N7T2@1224|Proteobacteria,1RSBI@1236|Gammaproteobacteria,1XV1A@135623|Vibrionales	135623|Vibrionales	S	monophosphate biosynthesis enzyme	yajL	-	3.5.1.124	ko:K03152	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DJ-1_PfpI
k141_5369_7	1348635.BBJY01000002_gene3492	3.6e-108	323.0	COG1893@1|root,COG1893@2|Bacteria,1P0AW@1224|Proteobacteria,1RR49@1236|Gammaproteobacteria,1XTJR@135623|Vibrionales	135623|Vibrionales	H	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid	panE	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008677,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605	1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000	-	-	-	ApbA,ApbA_C
k141_5369_8	1219076.N646_1473	2.29e-261	723.0	COG2211@1|root,COG2211@2|Bacteria,1QTSE@1224|Proteobacteria,1T1FN@1236|Gammaproteobacteria,1XSVM@135623|Vibrionales	135623|Vibrionales	G	COG0477 Permeases of the major facilitator superfamily	ampG	-	-	ko:K08218	ko01501,map01501	M00628	-	-	ko00000,ko00001,ko00002,ko02000	2.A.1.25	-	-	MFS_1
k141_5369_9	1348635.BBJY01000002_gene3488	9.62e-85	254.0	COG0652@1|root,COG0652@2|Bacteria,1R9ZQ@1224|Proteobacteria,1RP9U@1236|Gammaproteobacteria,1XTSG@135623|Vibrionales	135623|Vibrionales	M	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	rotA	-	5.2.1.8	ko:K03767	ko01503,ko04217,map01503,map04217	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04147	-	-	-	Pro_isomerase
k141_5369_10	675814.VIC_000696	4.37e-92	273.0	COG3056@1|root,COG3056@2|Bacteria,1MZ1N@1224|Proteobacteria,1RPG1@1236|Gammaproteobacteria,1XTP6@135623|Vibrionales	135623|Vibrionales	M	lipoprotein	VV2594	-	-	ko:K07286	-	-	-	-	ko00000	-	-	-	Lipoprotein_16
k141_5369_11	1219077.VAZ01S_010_00920	5.45e-171	489.0	COG2813@1|root,COG2813@2|Bacteria,1NEMR@1224|Proteobacteria,1RMXE@1236|Gammaproteobacteria,1XU8G@135623|Vibrionales	135623|Vibrionales	J	Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA	rlmG	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0008990,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0052916,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.174	ko:K11391	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	MTS,MTS_N
k141_5370_1	1121396.KB893112_gene1991	2.25e-109	330.0	COG0015@1|root,COG0015@2|Bacteria,1MV4B@1224|Proteobacteria,42MYS@68525|delta/epsilon subdivisions,2WJ2E@28221|Deltaproteobacteria,2MIET@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	purB	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ASL_C,Lyase_1
k141_5371_1	177437.HRM2_17100	9.59e-81	249.0	COG0052@1|root,COG0052@2|Bacteria,1MU33@1224|Proteobacteria,42M3Y@68525|delta/epsilon subdivisions,2WJH5@28221|Deltaproteobacteria,2MJCG@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Belongs to the universal ribosomal protein uS2 family	rpsB	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
k141_5371_2	96561.Dole_0475	8.05e-90	268.0	COG0264@1|root,COG0264@2|Bacteria,1MUS2@1224|Proteobacteria,42NNS@68525|delta/epsilon subdivisions,2WMS3@28221|Deltaproteobacteria,2MI7H@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
k141_5371_3	1121405.dsmv_2175	4.96e-113	331.0	COG0528@1|root,COG0528@2|Bacteria,1MV3N@1224|Proteobacteria,42M3X@68525|delta/epsilon subdivisions,2WJDF@28221|Deltaproteobacteria,2MIR4@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
k141_5371_4	96561.Dole_0477	1.04e-81	247.0	COG0233@1|root,COG0233@2|Bacteria,1N66T@1224|Proteobacteria,42NAA@68525|delta/epsilon subdivisions,2WNMN@28221|Deltaproteobacteria,2MJ2A@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
k141_5371_5	933262.AXAM01000048_gene2587	3.8e-95	286.0	COG0020@1|root,COG0020@2|Bacteria,1MVP1@1224|Proteobacteria,42PTV@68525|delta/epsilon subdivisions,2WMWK@28221|Deltaproteobacteria,2MIZD@213118|Desulfobacterales	28221|Deltaproteobacteria	I	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	uppS	GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
k141_5372_1	305900.GV64_20210	7.34e-76	239.0	COG3977@1|root,COG3977@2|Bacteria,1MVRW@1224|Proteobacteria,1RNK1@1236|Gammaproteobacteria,1XHID@135619|Oceanospirillales	135619|Oceanospirillales	E	catalyzes transamination of alanine, valine, and 2-aminobutyrate with their respective 2-keto acids	avtA	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
k141_5373_3	1449351.RISW2_21750	0.000485	44.3	COG0270@1|root,COG0270@2|Bacteria,1MV9D@1224|Proteobacteria,2TSWF@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family	-	-	2.1.1.37	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	M00035	R04858	RC00003,RC00332	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_methylase
k141_5373_5	382464.ABSI01000010_gene3716	6.43e-06	48.5	COG0323@1|root,COG0323@2|Bacteria	2|Bacteria	L	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_3
k141_5374_1	1167006.UWK_02111	4.22e-08	60.1	COG1639@1|root,COG1639@2|Bacteria,1PDZW@1224|Proteobacteria,42ZIC@68525|delta/epsilon subdivisions,2WUYH@28221|Deltaproteobacteria,2MNC2@213118|Desulfobacterales	28221|Deltaproteobacteria	T	HDOD domain	-	-	-	-	-	-	-	-	-	-	-	-	HDOD
k141_5374_2	926549.KI421517_gene3116	1.15e-121	358.0	COG0330@1|root,COG0330@2|Bacteria,4NEP5@976|Bacteroidetes,47K5Y@768503|Cytophagia	976|Bacteroidetes	O	prohibitin homologues	-	-	-	-	-	-	-	-	-	-	-	-	Band_7,Band_7_C
k141_5375_1	1232437.KL662014_gene1293	3.59e-60	212.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42N03@68525|delta/epsilon subdivisions,2WIX4@28221|Deltaproteobacteria,2MINP@213118|Desulfobacterales	28221|Deltaproteobacteria	NT	PFAM chemotaxis sensory transducer	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HBM,MCPsignal
k141_5375_2	1265505.ATUG01000001_gene3096	7.26e-60	189.0	COG0835@1|root,COG0835@2|Bacteria,1RAH1@1224|Proteobacteria,42QS2@68525|delta/epsilon subdivisions,2WMXG@28221|Deltaproteobacteria,2MJMH@213118|Desulfobacterales	28221|Deltaproteobacteria	NT	Two component signalling adaptor domain	-	-	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
k141_5376_1	338966.Ppro_2811	7.74e-155	485.0	COG0642@1|root,COG3850@1|root,COG2205@2|Bacteria,COG3850@2|Bacteria,1NRP8@1224|Proteobacteria,43CHE@68525|delta/epsilon subdivisions,2X7SI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
k141_5376_2	1121413.JMKT01000015_gene213	2.01e-81	260.0	COG0642@1|root,COG2205@2|Bacteria,1R7QH@1224|Proteobacteria,42PSC@68525|delta/epsilon subdivisions,2WKFW@28221|Deltaproteobacteria,2M8HM@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	PFAM ATP-binding region ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HATPase_c_5,PAS_8
k141_5377_1	305900.GV64_16030	1.91e-281	784.0	COG3593@1|root,COG3593@2|Bacteria,1MXAH@1224|Proteobacteria,1RYZW@1236|Gammaproteobacteria,1XM26@135619|Oceanospirillales	135619|Oceanospirillales	L	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_15
k141_5377_2	305900.GV64_16035	9.69e-27	107.0	COG0210@1|root,COG0210@2|Bacteria,1MXV9@1224|Proteobacteria,1S9EG@1236|Gammaproteobacteria,1XQ84@135619|Oceanospirillales	135619|Oceanospirillales	L	UvrD/REP helicase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_19
k141_5378_1	1120985.AUMI01000001_gene2084	9.91e-55	184.0	COG1159@1|root,COG1159@2|Bacteria,1TP3R@1239|Firmicutes,4H1WW@909932|Negativicutes	909932|Negativicutes	S	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism	era	-	-	ko:K03595	-	-	-	-	ko00000,ko03009,ko03029	-	-	-	KH_2,MMR_HSR1
k141_5378_2	1265505.ATUG01000001_gene3877	5.88e-57	186.0	COG0218@1|root,COG0218@2|Bacteria,1MY3Z@1224|Proteobacteria,42RJR@68525|delta/epsilon subdivisions,2WMK3@28221|Deltaproteobacteria,2MJT8@213118|Desulfobacterales	28221|Deltaproteobacteria	D	Necessary for normal cell division and for the maintenance of normal septation	engB	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K03978	-	-	-	-	ko00000,ko03036	-	-	-	MMR_HSR1
k141_5378_3	1265505.ATUG01000001_gene3880	2.38e-57	181.0	COG0139@1|root,COG0139@2|Bacteria,1MW67@1224|Proteobacteria,42SGH@68525|delta/epsilon subdivisions,2WP2B@28221|Deltaproteobacteria,2MK4J@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP	hisI	-	3.5.4.19,3.6.1.31	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04035,R04037	RC00002,RC01055	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1897	PRA-CH,PRA-PH
k141_5380_1	1268068.PG5_45890	2.43e-16	80.9	COG1961@1|root,COG1961@2|Bacteria,1N6DV@1224|Proteobacteria,1RYWS@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	COG1961 Site-specific recombinases, DNA invertase Pin homologs	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
k141_5380_2	675813.VIB_003045	8.73e-104	316.0	COG0606@1|root,COG0606@2|Bacteria,1MU4R@1224|Proteobacteria,1RMB9@1236|Gammaproteobacteria,1XTCR@135623|Vibrionales	135623|Vibrionales	O	ATPase with chaperone activity	comM	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
k141_5380_6	675815.VOA_000031	0.0	896.0	COG1171@1|root,COG1171@2|Bacteria,1MVWJ@1224|Proteobacteria,1RMY6@1236|Gammaproteobacteria,1XU5J@135623|Vibrionales	135623|Vibrionales	E	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA	ilvA	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP,Thr_dehydrat_C
k141_5380_7	1415778.JQMM01000001_gene1381	5.86e-23	100.0	COG0847@1|root,COG0847@2|Bacteria,1RAF1@1224|Proteobacteria,1S9PP@1236|Gammaproteobacteria,1J6J0@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	L	DNA polymerase III, epsilon subunit	-	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	RNase_T
k141_5380_8	1224318.DT73_25900	2.45e-244	694.0	COG2905@1|root,COG2905@2|Bacteria,1MW8U@1224|Proteobacteria,1RPSJ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	signal-transduction protein containing cAMP-binding and CBS domains	-	-	-	ko:K07182	-	-	-	-	ko00000	-	-	-	CBS,DUF294,DUF294_C
k141_5381_2	748449.Halha_1741	2.41e-278	773.0	COG1070@1|root,COG1070@2|Bacteria,1TP91@1239|Firmicutes,24A4Z@186801|Clostridia	186801|Clostridia	G	Carbohydrate kinase, FGGY family protein	araB	-	-	-	-	-	-	-	-	-	-	-	FGGY_C,FGGY_N
k141_5382_1	1122176.KB903539_gene1431	7.64e-39	138.0	2FG2V@1|root,347ZI@2|Bacteria,4P6MY@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_5385_1	223926.28806281	8.1e-93	283.0	COG0679@1|root,COG0679@2|Bacteria,1P2SH@1224|Proteobacteria,1S7N5@1236|Gammaproteobacteria,1XTMY@135623|Vibrionales	135623|Vibrionales	S	Membrane transport protein	VV2066	-	-	ko:K07088	-	-	-	-	ko00000	-	-	-	Mem_trans
k141_5385_2	345073.VC395_A0600	4.6e-88	265.0	COG1335@1|root,COG1335@2|Bacteria,1MUGW@1224|Proteobacteria,1RZBF@1236|Gammaproteobacteria,1Y2M3@135623|Vibrionales	135623|Vibrionales	Q	Isochorismatase family	-	-	3.5.1.19	ko:K08281	ko00760,ko01100,map00760,map01100	-	R01268	RC00100	ko00000,ko00001,ko01000	-	-	-	Isochorismatase
k141_5386_1	675813.VIB_001383	5.06e-163	471.0	COG1058@1|root,COG1058@2|Bacteria,1QUB2@1224|Proteobacteria,1RNXG@1236|Gammaproteobacteria,1XSVF@135623|Vibrionales	135623|Vibrionales	S	Belongs to the CinA family	yfaY	-	-	-	-	-	-	-	-	-	-	-	MoCF_biosynth
k141_5386_2	29495.EA26_06700	1.26e-61	195.0	COG2716@1|root,COG2716@2|Bacteria,1NAIN@1224|Proteobacteria,1SEAU@1236|Gammaproteobacteria,1XTJY@135623|Vibrionales	135623|Vibrionales	E	Glycine cleavage system regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	ACT_6
k141_5386_3	243277.VC_1248	1.39e-178	520.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMV2@1236|Gammaproteobacteria,1XV2M@135623|Vibrionales	135623|Vibrionales	T	methyl-accepting chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal,sCache_2
k141_5389_4	748727.CLJU_c17440	5.49e-95	278.0	COG3449@1|root,COG3449@2|Bacteria,1V73Y@1239|Firmicutes,24HGB@186801|Clostridia,36I41@31979|Clostridiaceae	186801|Clostridia	L	PFAM Bacterial transcription activator, effector binding	-	-	-	-	-	-	-	-	-	-	-	-	GyrI-like
k141_5389_5	1321784.HMPREF1987_00129	3.28e-191	551.0	COG0437@1|root,COG4624@1|root,COG0437@2|Bacteria,COG4624@2|Bacteria,1TQIR@1239|Firmicutes,248BS@186801|Clostridia,25R36@186804|Peptostreptococcaceae	186801|Clostridia	C	4Fe-4S binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fe_hyd_lg_C,Fer4,Fer4_6
k141_5389_6	1410668.JNKC01000004_gene238	4.86e-18	78.6	2EKY6@1|root,33EMQ@2|Bacteria,1VNMY@1239|Firmicutes,24UJM@186801|Clostridia,36SYD@31979|Clostridiaceae	186801|Clostridia	S	Thioredoxin-like [2Fe-2S] ferredoxin	-	-	-	-	-	-	-	-	-	-	-	-	2Fe-2S_thioredx
k141_5389_7	1238182.C882_2002	3.47e-157	448.0	COG0618@1|root,COG0618@2|Bacteria,1MX0B@1224|Proteobacteria,2TWVV@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	3'(2'),5'-bisphosphate nucleotidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_5389_8	1278309.KB907105_gene1406	6.82e-45	148.0	COG0251@1|root,COG0251@2|Bacteria,1MZ5K@1224|Proteobacteria,1S5WM@1236|Gammaproteobacteria,1XK86@135619|Oceanospirillales	135619|Oceanospirillales	J	endoribonuclease L-PSP	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
k141_5389_10	536232.CLM_2031	7.13e-222	628.0	COG0531@1|root,COG0531@2|Bacteria,1TRFS@1239|Firmicutes,248WW@186801|Clostridia,36EQ7@31979|Clostridiaceae	186801|Clostridia	E	amino acid	yjeM	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
k141_5389_11	99598.Cal7507_0956	3.24e-08	63.9	COG1135@1|root,COG1135@2|Bacteria,1G289@1117|Cyanobacteria,1HIGB@1161|Nostocales	1117|Cyanobacteria	P	P-loop Domain of unknown function (DUF2791)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2791
k141_5389_13	926561.KB900624_gene2714	1.23e-105	313.0	COG1192@1|root,COG1192@2|Bacteria,1U18X@1239|Firmicutes,24E35@186801|Clostridia,3WC9F@53433|Halanaerobiales	186801|Clostridia	D	Cellulose biosynthesis protein BcsQ	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
k141_5389_15	580327.Tthe_1038	1.62e-40	143.0	COG1268@1|root,COG1268@2|Bacteria,1VAY6@1239|Firmicutes,24HPU@186801|Clostridia,42GQC@68295|Thermoanaerobacterales	186801|Clostridia	S	PFAM BioY protein	bioY	-	-	ko:K03523	ko02010,map02010	M00581,M00582	-	-	ko00000,ko00001,ko00002,ko02000	2.A.88.1,2.A.88.2	-	-	BioY
k141_5389_16	929506.CbC4_0793	1.68e-65	210.0	COG2186@1|root,COG2186@2|Bacteria,1V2TU@1239|Firmicutes,24GA8@186801|Clostridia,36F6A@31979|Clostridiaceae	186801|Clostridia	K	GntR domain protein	-	-	-	ko:K05799	-	-	-	-	ko00000,ko03000	-	-	-	FCD,GntR
k141_5389_17	1121324.CLIT_23c03200	5.24e-222	629.0	COG1620@1|root,COG1620@2|Bacteria,1TQNM@1239|Firmicutes,2482V@186801|Clostridia,25QT6@186804|Peptostreptococcaceae	186801|Clostridia	C	L-lactate permease	lctP	-	-	ko:K03303	-	-	-	-	ko00000,ko02000	2.A.14	-	-	Lactate_perm
k141_5389_18	1121289.JHVL01000008_gene1238	1.97e-134	387.0	COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia,36FGA@31979|Clostridiaceae	186801|Clostridia	C	Electron transfer flavoprotein	etfB1	-	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
k141_5389_19	1304284.L21TH_1081	7.71e-210	589.0	COG2025@1|root,COG2025@2|Bacteria,1TPC8@1239|Firmicutes,247NF@186801|Clostridia,36DD9@31979|Clostridiaceae	186801|Clostridia	C	Electron transfer flavoprotein	etfA2	-	-	ko:K03522	-	-	-	-	ko00000,ko04147	-	-	-	ETF,ETF_alpha
k141_5389_20	1476973.JMMB01000007_gene944	1.58e-261	725.0	COG0277@1|root,COG0277@2|Bacteria,1TPBC@1239|Firmicutes,24A99@186801|Clostridia,25SG3@186804|Peptostreptococcaceae	186801|Clostridia	C	FAD linked oxidases, C-terminal domain	glcD1	-	1.1.3.15	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
k141_5389_21	1128398.Curi_c04040	9.79e-90	272.0	COG2188@1|root,COG2188@2|Bacteria,1UWXE@1239|Firmicutes,25MUS@186801|Clostridia,26C29@186813|unclassified Clostridiales	186801|Clostridia	K	UTRA domain	-	-	-	ko:K03710	-	-	-	-	ko00000,ko03000	-	-	-	GntR,UTRA
k141_5389_22	1128398.Curi_c04060	9.61e-226	634.0	COG0402@1|root,COG0402@2|Bacteria,1TP43@1239|Firmicutes,248IX@186801|Clostridia,267TX@186813|unclassified Clostridiales	186801|Clostridia	F	Amidohydrolase family	atzB	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
k141_5389_23	1128398.Curi_c04050	5.96e-75	233.0	COG2364@1|root,COG2364@2|Bacteria,1V47R@1239|Firmicutes,24AXT@186801|Clostridia	186801|Clostridia	S	membrane	-	-	-	ko:K07149	-	-	-	-	ko00000	-	-	-	YitT_membrane
k141_5389_24	1122931.AUAE01000030_gene843	5.85e-09	57.8	2EG60@1|root,339XW@2|Bacteria,4NY08@976|Bacteroidetes,2FS7K@200643|Bacteroidia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Inhibitor_I42
k141_474_3	55601.VANGNB10_cI0133	6.54e-78	237.0	COG2856@1|root,COG2856@2|Bacteria,1PCS7@1224|Proteobacteria,1TJTG@1236|Gammaproteobacteria,1Y1NK@135623|Vibrionales	135623|Vibrionales	E	Pfam:DUF955	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M78
k141_474_4	1027273.GZ77_17060	1.21e-20	92.0	2ER11@1|root,33IKJ@2|Bacteria,1NQCW@1224|Proteobacteria,1SJ6Y@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_474_6	223926.28808081	1.81e-156	445.0	COG0204@1|root,COG0204@2|Bacteria,1MVWG@1224|Proteobacteria,1RR21@1236|Gammaproteobacteria,1XTJU@135623|Vibrionales	135623|Vibrionales	I	1-acyl-sn-glycerol-3-phosphate acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
k141_474_7	1188252.AJYK01000022_gene1323	1.73e-82	250.0	COG1651@1|root,COG1651@2|Bacteria,1RGWH@1224|Proteobacteria,1S5WA@1236|Gammaproteobacteria,1XTXK@135623|Vibrionales	135623|Vibrionales	O	Thiol disulfide interchange protein	dsbA	GO:0003674,GO:0003756,GO:0003824,GO:0005575,GO:0005623,GO:0006457,GO:0008150,GO:0009987,GO:0016853,GO:0016860,GO:0016864,GO:0042597,GO:0044464,GO:0140096	-	ko:K03673	ko01503,map01503	M00728	-	-	ko00000,ko00001,ko00002,ko03110	-	-	-	DSBA
k141_474_8	675816.VIA_000634	1.02e-183	517.0	COG2334@1|root,COG2334@2|Bacteria,1MU2Q@1224|Proteobacteria,1RNHI@1236|Gammaproteobacteria,1XU7N@135623|Vibrionales	135623|Vibrionales	F	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response	srkA	-	-	-	-	-	-	-	-	-	-	-	APH
k141_474_9	675815.VOA_000021	1.84e-52	165.0	COG3084@1|root,COG3084@2|Bacteria,1N026@1224|Proteobacteria,1S93G@1236|Gammaproteobacteria,1XXV3@135623|Vibrionales	135623|Vibrionales	S	protein conserved in bacteria	yihD	-	-	ko:K09896	-	-	-	-	ko00000	-	-	-	DUF1040
k141_474_10	575788.VS_3134	4.15e-134	386.0	COG4326@1|root,COG4326@2|Bacteria,1RB4P@1224|Proteobacteria,1S3CE@1236|Gammaproteobacteria,1XTH8@135623|Vibrionales	135623|Vibrionales	S	COG4326 Sporulation control protein	spoOM	-	-	ko:K06377	-	-	-	-	ko00000	-	-	-	Spo0M
k141_474_11	945550.VISI1226_17185	5.08e-283	781.0	COG0168@1|root,COG0168@2|Bacteria,1MUIJ@1224|Proteobacteria,1RMN6@1236|Gammaproteobacteria,1XUGG@135623|Vibrionales	135623|Vibrionales	P	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA	trkH-1	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
k141_474_12	1348635.BBJY01000022_gene1909	1.3e-301	826.0	COG0569@1|root,COG0569@2|Bacteria,1MW8R@1224|Proteobacteria,1RNVQ@1236|Gammaproteobacteria,1XTKZ@135623|Vibrionales	135623|Vibrionales	P	Potassium transporter peripheral membrane component	trkA	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
k141_474_13	945543.VIBR0546_09232	2.08e-240	668.0	COG0144@1|root,COG0781@1|root,COG0144@2|Bacteria,COG0781@2|Bacteria,1MWPE@1224|Proteobacteria,1RN8X@1236|Gammaproteobacteria,1XUH8@135623|Vibrionales	135623|Vibrionales	J	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA	rsmB	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.176	ko:K03500	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F,NusB
k141_474_14	617140.AJZE01000048_gene3201	3.97e-184	517.0	COG0223@1|root,COG0223@2|Bacteria,1MU4Q@1224|Proteobacteria,1RP1T@1236|Gammaproteobacteria,1XTX0@135623|Vibrionales	135623|Vibrionales	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	GO:0003674,GO:0003824,GO:0004479,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006418,GO:0006431,GO:0006464,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019752,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
k141_474_16	675813.VIB_003033	7.35e-137	401.0	COG0758@1|root,COG0758@2|Bacteria,1MVF6@1224|Proteobacteria,1RPJE@1236|Gammaproteobacteria,1XSI4@135623|Vibrionales	135623|Vibrionales	LU	Rossmann fold nucleotide-binding protein involved in DNA uptake	smf	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A
k141_474_17	675813.VIB_003032	1.79e-92	272.0	COG2922@1|root,COG2922@2|Bacteria,1RD5F@1224|Proteobacteria,1S43X@1236|Gammaproteobacteria,1XTHN@135623|Vibrionales	135623|Vibrionales	S	Belongs to the Smg family	smg	-	-	ko:K03747	-	-	-	-	ko00000	-	-	-	DUF494
k141_474_18	1219076.N646_2136	1.87e-59	191.0	COG0551@1|root,COG0551@2|Bacteria,1MX2E@1224|Proteobacteria,1RQ85@1236|Gammaproteobacteria,1XUJR@135623|Vibrionales	135623|Vibrionales	L	COG0551 Zn-finger domain associated with topoisomerase type I	yrdD	-	-	ko:K07479	-	-	-	-	ko00000	-	-	-	zf-C4_Topoisom
k141_474_19	1136163.M565_ctg4P344	3.56e-230	638.0	COG0026@1|root,COG0026@2|Bacteria,1MU70@1224|Proteobacteria,1RQEI@1236|Gammaproteobacteria,1XU8Y@135623|Vibrionales	135623|Vibrionales	F	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)	purK	GO:0003674,GO:0003824,GO:0004638,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.4.18	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07404	RC01927	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp
k141_474_20	1280001.BAOA01000052_gene1652	1.41e-95	280.0	COG0041@1|root,COG0041@2|Bacteria,1RCWJ@1224|Proteobacteria,1S3VN@1236|Gammaproteobacteria,1XUDA@135623|Vibrionales	135623|Vibrionales	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purE	GO:0003674,GO:0003824,GO:0004638,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC
k141_474_21	945550.VISI1226_17240	1.07e-97	287.0	COG0009@1|root,COG0009@2|Bacteria,1MVPM@1224|Proteobacteria,1S610@1236|Gammaproteobacteria,1XV14@135623|Vibrionales	135623|Vibrionales	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-) CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate	tsaC	GO:0000049,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006450,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0065007,GO:0065008,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	Sua5_yciO_yrdC
k141_474_22	1348635.BBJY01000022_gene1898	3.12e-190	531.0	COG0408@1|root,COG0408@2|Bacteria,1MWMF@1224|Proteobacteria,1RMM8@1236|Gammaproteobacteria,1XT68@135623|Vibrionales	135623|Vibrionales	H	Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX	hemF	GO:0003674,GO:0003824,GO:0004109,GO:0005488,GO:0005515,GO:0006725,GO:0006778,GO:0006779,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016627,GO:0016634,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042802,GO:0042803,GO:0044237,GO:0044249,GO:0044271,GO:0046483,GO:0046983,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	1.3.3.3	ko:K00228	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03220	RC00884	ko00000,ko00001,ko00002,ko01000	-	-	-	Coprogen_oxidas
k141_474_23	55601.VANGNB10_cI0065	2.89e-147	420.0	COG0169@1|root,COG0169@2|Bacteria,1MVH4@1224|Proteobacteria,1RPB7@1236|Gammaproteobacteria,1XTNJ@135623|Vibrionales	135623|Vibrionales	E	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	aroE	GO:0000166,GO:0003674,GO:0003824,GO:0004764,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	-	Shikimate_DH,Shikimate_dh_N
k141_474_24	672.VV93_v1c29370	1.48e-26	100.0	2E6QS@1|root,331AY@2|Bacteria,1N7X6@1224|Proteobacteria,1SC8J@1236|Gammaproteobacteria,1XYV9@135623|Vibrionales	135623|Vibrionales	S	Protein of unknown function (DUF1488)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1488
k141_474_25	675812.VHA_000046	1.68e-78	238.0	COG0663@1|root,COG0663@2|Bacteria,1RD76@1224|Proteobacteria,1RPB6@1236|Gammaproteobacteria,1XU2T@135623|Vibrionales	135623|Vibrionales	S	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily	yrdA	-	-	-	-	-	-	-	-	-	-	-	Hexapep
k141_4508_1	177437.HRM2_10980	2.64e-84	265.0	COG5000@1|root,COG5000@2|Bacteria,1QWMS@1224|Proteobacteria,43BSR@68525|delta/epsilon subdivisions,2X73I@28221|Deltaproteobacteria,2MPJM@213118|Desulfobacterales	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
k141_4134_2	675816.VIA_001062	4.33e-226	627.0	COG4174@1|root,COG4174@2|Bacteria,1MVKE@1224|Proteobacteria,1RMH8@1236|Gammaproteobacteria,1XT3P@135623|Vibrionales	135623|Vibrionales	P	transport system, permease component	-	-	-	ko:K13894	ko02010,map02010	M00349	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.21,3.A.1.5.24	-	-	BPD_transp_1
k141_4134_3	870967.VIS19158_10499	4.96e-120	362.0	COG4166@1|root,COG4166@2|Bacteria,1MUVU@1224|Proteobacteria,1RMA1@1236|Gammaproteobacteria,1XUMM@135623|Vibrionales	135623|Vibrionales	E	ABC-type oligopeptide transport system, periplasmic component	-	-	-	ko:K13893	ko02010,map02010	M00349	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.21,3.A.1.5.24	-	-	SBP_bac_5
k141_2761_2	1296415.JACC01000002_gene3403	2.15e-102	331.0	COG2133@1|root,COG3250@1|root,COG5520@1|root,COG2133@2|Bacteria,COG3250@2|Bacteria,COG5520@2|Bacteria,4NEG7@976|Bacteroidetes,1HZPC@117743|Flavobacteriia	976|Bacteroidetes	M	O-Glycosyl hydrolase family 30	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,Glyco_hydr_30_2,Glyco_hydro_30C
k141_2761_3	945543.VIBR0546_21655	3.39e-90	274.0	COG1943@1|root,COG1943@2|Bacteria,1MVUV@1224|Proteobacteria,1RNIV@1236|Gammaproteobacteria,1XTXM@135623|Vibrionales	135623|Vibrionales	L	COG1943 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_475_2	1348635.BBJY01000004_gene2919	4.68e-299	824.0	COG0477@1|root,COG2814@2|Bacteria,1MU1I@1224|Proteobacteria,1RNTG@1236|Gammaproteobacteria,1XTM8@135623|Vibrionales	135623|Vibrionales	P	COG0477 Permeases of the major facilitator superfamily	emrB	-	-	ko:K03446	-	M00701	-	-	ko00000,ko00002,ko02000	2.A.1.3	-	-	MFS_1,SATase_N
k141_4510_1	292563.Cyast_2140	3.4e-41	164.0	COG0515@1|root,COG2199@1|root,COG2203@1|root,COG3899@1|root,COG0515@2|Bacteria,COG2203@2|Bacteria,COG3706@2|Bacteria,COG3899@2|Bacteria,1GBKM@1117|Cyanobacteria	1117|Cyanobacteria	KLT	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GAF,GGDEF,HATPase_c,HisKA,PAS_3,PAS_4,Pkinase,Response_reg,SpoIIE
k141_3512_3	345073.VC395_A0779	2.16e-239	678.0	COG0737@1|root,COG0737@2|Bacteria,1MX03@1224|Proteobacteria,1RPX3@1236|Gammaproteobacteria,1XU8U@135623|Vibrionales	135623|Vibrionales	F	Belongs to the 5'-nucleotidase family	-	-	3.1.3.5	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	5_nucleotid_C,Metallophos
k141_3512_4	55601.VANGNB10_cII0535	1.09e-290	805.0	COG1196@1|root,COG3593@1|root,COG1196@2|Bacteria,COG3593@2|Bacteria,1N2CB@1224|Proteobacteria,1RQN2@1236|Gammaproteobacteria,1XSQI@135623|Vibrionales	135623|Vibrionales	L	ATP-dependent endonuclease of the OLD family	ybjD	-	-	ko:K07459	-	-	-	-	ko00000	-	-	-	DUF2813
k141_3512_5	675813.VIB_002194	1.33e-133	388.0	COG0583@1|root,COG0583@2|Bacteria,1MWVU@1224|Proteobacteria,1RPT8@1236|Gammaproteobacteria,1XTZM@135623|Vibrionales	135623|Vibrionales	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
k141_3512_6	1219065.VPR01S_07_01250	8.95e-131	387.0	COG0517@1|root,COG2116@1|root,COG0517@2|Bacteria,COG2116@2|Bacteria,1MU0W@1224|Proteobacteria,1RQ6K@1236|Gammaproteobacteria,1XUCS@135623|Vibrionales	135623|Vibrionales	P	COG2116 Formate nitrite family of transporters	VVA0737	-	-	ko:K06212	-	-	-	-	ko00000,ko02000	1.A.16.1.1,1.A.16.1.3	-	-	CBS,Form_Nir_trans
k141_3512_7	675815.VOA_001568	2.79e-108	316.0	2AVVY@1|root,31MPS@2|Bacteria,1QJH3@1224|Proteobacteria,1THGW@1236|Gammaproteobacteria,1XVRR@135623|Vibrionales	135623|Vibrionales	-	-	VCA0537	-	-	-	-	-	-	-	-	-	-	-	-
k141_3512_8	675816.VIA_001186	1.17e-69	223.0	COG2200@1|root,COG2200@2|Bacteria,1N50H@1224|Proteobacteria,1SYN8@1236|Gammaproteobacteria,1XUYQ@135623|Vibrionales	135623|Vibrionales	T	COG2200 FOG EAL domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL
k141_3512_9	1082705.JIBP01000003_gene2406	8.17e-63	196.0	2E2XV@1|root,32XYR@2|Bacteria,1N0JU@1224|Proteobacteria,1SC47@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_3512_12	1348635.BBJY01000010_gene1255	3.24e-192	557.0	COG0564@1|root,COG0564@2|Bacteria,1MVJ5@1224|Proteobacteria,1RN61@1236|Gammaproteobacteria,1XSMM@135623|Vibrionales	135623|Vibrionales	J	COG0564 Pseudouridylate synthases, 23S RNA-specific	-	-	5.4.99.28,5.4.99.29	ko:K06177	-	-	-	-	ko00000,ko01000,ko03009,ko03016	-	-	-	PseudoU_synth_2
k141_3512_14	1319815.HMPREF0202_01039	4.7e-172	498.0	COG1012@1|root,COG1012@2|Bacteria,379E9@32066|Fusobacteria	32066|Fusobacteria	C	belongs to the iron- containing alcohol dehydrogenase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldedh
k141_3512_15	1123057.P872_25535	4.06e-17	87.4	COG2207@1|root,COG2207@2|Bacteria,4NF63@976|Bacteroidetes,47N1B@768503|Cytophagia	976|Bacteroidetes	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	AraC_N,HTH_18,HTH_AraC
k141_3512_16	595494.Tola_1744	1.7e-44	151.0	COG1846@1|root,COG1846@2|Bacteria,1N7BV@1224|Proteobacteria,1S2AX@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	transcriptional regulator	marR	GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0042221,GO:0044212,GO:0045892,GO:0045934,GO:0046677,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051716,GO:0060255,GO:0065007,GO:0070887,GO:0071236,GO:0080090,GO:0097159,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141	-	ko:K03712	-	-	-	-	ko00000,ko03000	-	-	-	MarR,MarR_2
k141_3512_17	1283284.AZUK01000001_gene271	2.08e-158	465.0	COG1538@1|root,COG1538@2|Bacteria,1MUZZ@1224|Proteobacteria,1RQEP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	MU	RND efflux system, outer membrane lipoprotein	mdtP	-	-	-	-	-	-	-	-	-	-	-	OEP
k141_3512_18	1283284.AZUK01000001_gene272	7.38e-172	492.0	COG1566@1|root,COG1566@2|Bacteria,1MU7I@1224|Proteobacteria,1RMAD@1236|Gammaproteobacteria,1Y5PB@135624|Aeromonadales	135624|Aeromonadales	V	HlyD membrane-fusion protein of T1SS	-	-	-	ko:K03543	-	M00701	-	-	ko00000,ko00002,ko02000	8.A.1.1	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
k141_3512_19	595494.Tola_1747	9.37e-273	756.0	COG0477@1|root,COG2814@2|Bacteria,1MU1I@1224|Proteobacteria,1RNTG@1236|Gammaproteobacteria,1Y5KH@135624|Aeromonadales	135624|Aeromonadales	P	major facilitator superfamily	-	-	-	ko:K03446,ko:K08170	-	M00701,M00702	-	-	ko00000,ko00002,ko01504,ko02000	2.A.1.3,2.A.1.3.23,2.A.1.3.59	-	-	MFS_1
k141_3512_20	1123511.KB905860_gene2260	0.0	1044.0	COG0446@1|root,COG1902@1|root,COG0446@2|Bacteria,COG1902@2|Bacteria,1TPM6@1239|Firmicutes,4H3EB@909932|Negativicutes	909932|Negativicutes	C	PFAM NADH flavin oxidoreductase NADH oxidase, FAD-dependent pyridine nucleotide-disulfide oxidoreductase, Pyridine nucleotide-disulphide oxidoreductase, FAD NAD(P)-binding domain	-	-	1.3.1.31	ko:K10797	ko00360,ko01120,map00360,map01120	-	R02252	RC00669	ko00000,ko00001,ko01000	-	-	-	Oxidored_FMN,Pyr_redox_2
k141_3512_21	1219065.VPR01S_01_03690	6.32e-22	87.4	2AWN3@1|root,31NIV@2|Bacteria,1QK9H@1224|Proteobacteria,1TID0@1236|Gammaproteobacteria,1XYWJ@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_3512_22	288000.BBta_6814	0.0	1334.0	COG1020@1|root,COG1020@2|Bacteria,1QK4F@1224|Proteobacteria,2TRUN@28211|Alphaproteobacteria,3JQV9@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	Q	Phosphopantetheine attachment site	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding
k141_4862_3	298386.PBPRA0156	4.69e-46	150.0	COG0607@1|root,COG0607@2|Bacteria,1MZPW@1224|Proteobacteria,1S94C@1236|Gammaproteobacteria,1XXT2@135623|Vibrionales	135623|Vibrionales	P	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide	glpE	GO:0003674,GO:0003824	2.8.1.1	ko:K02439	ko00920,ko01110,ko01120,map00920,map01110,map01120	-	R01931	-	ko00000,ko00001,ko01000	-	-	-	Rhodanese
k141_4862_4	55601.VANGNB10_cI0106	4.02e-119	349.0	COG0705@1|root,COG0705@2|Bacteria,1MYPM@1224|Proteobacteria,1RN1K@1236|Gammaproteobacteria,1XSZ8@135623|Vibrionales	135623|Vibrionales	S	membrane protein (homolog of Drosophila rhomboid)	glpG	-	-	ko:K02441	-	-	-	-	ko00000	-	-	-	Rhomboid,Rhomboid_N
k141_3826_1	194439.CT1068	3.66e-61	220.0	COG1330@1|root,COG1330@2|Bacteria,1FEMY@1090|Chlorobi	1090|Chlorobi	L	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity	recC	-	3.1.11.5	ko:K03583	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_V_gamma
k141_1113_2	1304885.AUEY01000033_gene1899	2.72e-121	366.0	COG3203@1|root,COG3203@2|Bacteria,1PJNW@1224|Proteobacteria,42TCM@68525|delta/epsilon subdivisions,2WPPQ@28221|Deltaproteobacteria,2MNBT@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_1113_3	1304885.AUEY01000033_gene1898	4.77e-34	122.0	COG0226@1|root,COG0226@2|Bacteria,1N19C@1224|Proteobacteria,42VP7@68525|delta/epsilon subdivisions,2WSZW@28221|Deltaproteobacteria,2MKX5@213118|Desulfobacterales	28221|Deltaproteobacteria	P	COG0226 ABC-type phosphate transport system, periplasmic component	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_4536_1	648757.Rvan_0421	9.64e-16	87.4	COG1835@1|root,COG1835@2|Bacteria,1MV2W@1224|Proteobacteria,2TRT8@28211|Alphaproteobacteria,3N824@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	I	PFAM acyltransferase 3	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
k141_4536_3	672.VV93_v1c03220	2.46e-45	152.0	COG0394@1|root,COG0394@2|Bacteria,1N0DZ@1224|Proteobacteria,1S92S@1236|Gammaproteobacteria,1XXJG@135623|Vibrionales	135623|Vibrionales	T	Belongs to the low molecular weight phosphotyrosine protein phosphatase family	wzb	-	3.1.3.48	ko:K01104,ko:K20945	ko05111,map05111	-	-	-	ko00000,ko00001,ko01000	-	-	-	LMWPc
k141_4536_4	1348635.BBJY01000002_gene3532	3.89e-95	282.0	COG3726@1|root,COG3726@2|Bacteria,1MUT6@1224|Proteobacteria,1RNHZ@1236|Gammaproteobacteria,1XT32@135623|Vibrionales	135623|Vibrionales	S	membrane protein affecting hemolysin expression	smp	-	-	ko:K07186	-	-	-	-	ko00000	-	-	-	SMP_2
k141_4536_5	55601.VANGNB10_cI2124c	4.26e-155	444.0	COG0560@1|root,COG0560@2|Bacteria,1MWA3@1224|Proteobacteria,1RNJE@1236|Gammaproteobacteria,1XTII@135623|Vibrionales	135623|Vibrionales	E	phosphoserine phosphatase	serB	GO:0001505,GO:0003674,GO:0003824,GO:0004647,GO:0006082,GO:0006520,GO:0006544,GO:0006545,GO:0006563,GO:0006564,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0017144,GO:0019752,GO:0042133,GO:0042136,GO:0042578,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	3.1.3.3	ko:K01079	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R00582	RC00017	ko00000,ko00001,ko00002,ko01000,ko01009	-	-	-	HAD,Hydrolase
k141_4536_6	675815.VOA_002666	1.58e-312	880.0	2C5UW@1|root,2Z80T@2|Bacteria,1MXH2@1224|Proteobacteria,1RR1H@1236|Gammaproteobacteria,1XU04@135623|Vibrionales	135623|Vibrionales	S	PilZ domain	-	-	-	-	-	-	-	-	-	-	-	-	PilZ
k141_4536_7	675814.VIC_000706	4.33e-304	833.0	COG1066@1|root,COG1066@2|Bacteria,1MUJQ@1224|Proteobacteria,1RN2E@1236|Gammaproteobacteria,1XSUR@135623|Vibrionales	135623|Vibrionales	O	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function	radA	-	-	ko:K04485	-	-	-	-	ko00000,ko03400	-	-	-	AAA_25,ATPase,ChlI
k141_4536_8	1219080.VEZ01S_47_00110	0.0	1278.0	COG0480@1|root,COG0480@2|Bacteria,1MUCV@1224|Proteobacteria,1RNNJ@1236|Gammaproteobacteria,1XTQW@135623|Vibrionales	135623|Vibrionales	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA2	GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
k141_4536_9	414684.RC1_2380	1.02e-120	365.0	COG3550@1|root,COG3550@2|Bacteria,1N458@1224|Proteobacteria,2TVQF@28211|Alphaproteobacteria,2JT52@204441|Rhodospirillales	204441|Rhodospirillales	S	HipA N-terminal domain	-	-	2.7.11.1	ko:K07154	-	-	-	-	ko00000,ko01000,ko01001,ko02048	-	-	-	Couple_hipA,HipA_C
k141_4536_10	714943.Mucpa_4033	8.9e-09	56.2	COG1396@1|root,COG1396@2|Bacteria,4NRWV@976|Bacteroidetes,1ITAB@117747|Sphingobacteriia	976|Bacteroidetes	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19,HTH_3,HTH_31
k141_1114_1	413816.BBJP01000092_gene3045	6.05e-31	125.0	COG2217@1|root,arCOG02764@1|root,arCOG01576@2157|Archaea,arCOG02764@2157|Archaea,2XTD8@28890|Euryarchaeota,23U8V@183963|Halobacteria	183963|Halobacteria	P	COG2217 Cation transport ATPase	-	-	3.6.3.3,3.6.3.5	ko:K01534	-	-	-	-	ko00000,ko01000	3.A.3.6	-	-	E1-E2_ATPase,HMA,Hydrolase
k141_2777_1	1173022.Cri9333_3935	2.64e-124	365.0	COG0667@1|root,COG0667@2|Bacteria,1G1J4@1117|Cyanobacteria,1H8SS@1150|Oscillatoriales	1117|Cyanobacteria	C	PFAM aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
k141_2777_2	1121396.KB893012_gene4012	1.84e-231	674.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,42M2R@68525|delta/epsilon subdivisions,2WJ4J@28221|Deltaproteobacteria,2MHN2@213118|Desulfobacterales	28221|Deltaproteobacteria	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
k141_1456_1	192952.MM_0729	6.77e-35	135.0	COG0840@1|root,arCOG03642@2157|Archaea	2157|Archaea	NT	PFAM Cache, type 2 domain protein	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	sCache_2
k141_1456_2	1238450.VIBNISOn1_1720120	2.26e-10	71.6	COG0840@1|root,COG0840@2|Bacteria,1R6T7@1224|Proteobacteria,1RZC5@1236|Gammaproteobacteria,1XU93@135623|Vibrionales	135623|Vibrionales	NT	methyl-accepting chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal
k141_1456_3	575788.VS_1638	1.27e-76	243.0	COG1230@1|root,COG1230@2|Bacteria,1MVQB@1224|Proteobacteria,1RMR8@1236|Gammaproteobacteria,1XSH2@135623|Vibrionales	135623|Vibrionales	P	Cation efflux family	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux
k141_1456_4	1304885.AUEY01000021_gene3462	1e-176	508.0	COG0427@1|root,COG0427@2|Bacteria,1MUGE@1224|Proteobacteria,42MHC@68525|delta/epsilon subdivisions,2WINZ@28221|Deltaproteobacteria,2MI87@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM Acetyl-CoA hydrolase transferase	-	-	-	-	-	-	-	-	-	-	-	iAF987.Gmet_3304	AcetylCoA_hyd_C,AcetylCoA_hydro,Acetyltransf_1
k141_1456_5	1304885.AUEY01000007_gene1360	3.04e-76	243.0	COG0589@1|root,COG0589@2|Bacteria,1REA3@1224|Proteobacteria,42RXY@68525|delta/epsilon subdivisions,2WNM6@28221|Deltaproteobacteria,2MKDX@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
k141_1456_6	156889.Mmc1_2492	1.44e-14	80.5	COG0840@1|root,COG4564@1|root,COG0840@2|Bacteria,COG4564@2|Bacteria,1MU9B@1224|Proteobacteria,2TQR7@28211|Alphaproteobacteria	2|Bacteria	T	methyl-accepting chemotaxis protein	-	-	-	ko:K03406,ko:K05875,ko:K05876,ko:K07216	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CZB,Cache_3-Cache_2,HAMP,Hemerythrin,MCPsignal,dCache_2,sCache_2
k141_2778_1	349521.HCH_04941	1.01e-84	270.0	COG1835@1|root,COG1835@2|Bacteria,1MV2W@1224|Proteobacteria,1RQS2@1236|Gammaproteobacteria,1XNKK@135619|Oceanospirillales	135619|Oceanospirillales	I	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
k141_1457_1	1232437.KL662043_gene2219	1.13e-103	318.0	COG1166@1|root,COG1166@2|Bacteria,1MU80@1224|Proteobacteria,42M2B@68525|delta/epsilon subdivisions,2WJDZ@28221|Deltaproteobacteria,2MJ4U@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Pyridoxal-dependent decarboxylase, pyridoxal binding domain	speA	-	4.1.1.19	ko:K01585	ko00330,ko01100,map00330,map01100	M00133	R00566	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N
k141_1116_1	313606.M23134_04933	1.06e-71	243.0	COG0841@1|root,COG0841@2|Bacteria,4NDZG@976|Bacteroidetes,47N6C@768503|Cytophagia	976|Bacteroidetes	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k141_4537_1	1304885.AUEY01000052_gene1554	4.85e-255	727.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,42P9Y@68525|delta/epsilon subdivisions,2WM6A@28221|Deltaproteobacteria,2MJCC@213118|Desulfobacterales	28221|Deltaproteobacteria	NTU	General secretory system II protein E domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,T2SSE,T2SSE_N
k141_754_1	106648.BBLJ01000068_gene4348	8.95e-13	79.0	291Y7@1|root,2ZPHR@2|Bacteria,1P5NY@1224|Proteobacteria,1SU2A@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_754_2	1249634.D781_0919	5.41e-45	149.0	COG1376@1|root,COG1376@2|Bacteria,1N7UV@1224|Proteobacteria,1SG1E@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF2778)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2778
k141_754_3	932213.SPM24T3_23417	2.43e-25	99.0	2DPH4@1|root,33228@2|Bacteria,1N1J1@1224|Proteobacteria,1SJ9K@1236|Gammaproteobacteria,4058V@613|Serratia	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_754_4	1348635.BBJY01000005_gene3236	5.85e-205	590.0	COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,1SKTW@1236|Gammaproteobacteria,1Y32G@135623|Vibrionales	135623|Vibrionales	T	COG0642 Signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
k141_754_5	675813.VIB_001296	4.37e-158	457.0	COG3287@1|root,COG3287@2|Bacteria,1R825@1224|Proteobacteria,1S25E@1236|Gammaproteobacteria,1Y2U6@135623|Vibrionales	135623|Vibrionales	S	FIST N domain	-	-	-	-	-	-	-	-	-	-	-	-	FIST,FIST_C
k141_754_6	1051646.VITU9109_03852	1.93e-163	459.0	COG0664@1|root,COG0664@2|Bacteria,1MVGE@1224|Proteobacteria,1RPTB@1236|Gammaproteobacteria,1XT6M@135623|Vibrionales	135623|Vibrionales	K	COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases	fnr	-	-	ko:K01420	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
k141_754_7	870967.VIS19158_08042	4.84e-172	486.0	COG0589@1|root,COG0589@2|Bacteria,1MVZS@1224|Proteobacteria,1RPAE@1236|Gammaproteobacteria,1XSRX@135623|Vibrionales	135623|Vibrionales	T	COG0589 Universal stress protein UspA and related nucleotide-binding proteins	uspE	-	-	ko:K14055	-	-	-	-	ko00000	-	-	-	Usp
k141_754_8	945543.VIBR0546_00275	9.63e-152	434.0	COG0037@1|root,COG0037@2|Bacteria,1MW5Q@1224|Proteobacteria,1RN2H@1236|Gammaproteobacteria,1XTQ4@135623|Vibrionales	135623|Vibrionales	J	Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system	ttcA	-	-	ko:K14058	-	-	-	-	ko00000,ko03016	-	-	-	ATP_bind_3
k141_754_10	1348635.BBJY01000005_gene3222	1.03e-81	253.0	COG2992@1|root,COG2992@2|Bacteria,1RD3U@1224|Proteobacteria,1S3RA@1236|Gammaproteobacteria,1XUFN@135623|Vibrionales	135623|Vibrionales	S	BAX protein	bax	-	-	ko:K03796	-	-	-	-	ko00000	-	GH73	-	Glucosaminidase
k141_754_11	575788.VS_1473	4.42e-66	214.0	COG5473@1|root,COG5473@2|Bacteria,1N3T0@1224|Proteobacteria,1SEVY@1236|Gammaproteobacteria,1XTIE@135623|Vibrionales	135623|Vibrionales	-	-	VP1530	-	-	-	-	-	-	-	-	-	-	-	-
k141_754_12	675816.VIA_003006	2.41e-204	573.0	COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,1RNPX@1236|Gammaproteobacteria,1XT3F@135623|Vibrionales	135623|Vibrionales	P	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system	potA	GO:0003674,GO:0003824,GO:0005215,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0015203,GO:0015399,GO:0015405,GO:0015417,GO:0015695,GO:0015696,GO:0015846,GO:0015847,GO:0015848,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0042623,GO:0042626,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:1902047	3.6.3.31	ko:K11072	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.11.1	-	-	ABC_tran,TOBE_2
k141_754_13	1205908.AKXW01000092_gene2437	7.7e-164	463.0	COG1176@1|root,COG1176@2|Bacteria,1MVGM@1224|Proteobacteria,1RNNZ@1236|Gammaproteobacteria,1XSQ9@135623|Vibrionales	135623|Vibrionales	P	Spermidine putrescine ABC transporter	potB	-	-	ko:K11071	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	BPD_transp_1
k141_754_14	675815.VOA_000087	1.47e-139	399.0	COG1177@1|root,COG1177@2|Bacteria,1MVC5@1224|Proteobacteria,1RQB7@1236|Gammaproteobacteria,1XT48@135623|Vibrionales	135623|Vibrionales	P	Spermidine putrescine ABC transporter	potC	-	-	ko:K11070	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	BPD_transp_1
k141_754_16	1238450.VIBNISOn1_1720030	2.21e-127	367.0	COG0846@1|root,COG0846@2|Bacteria,1MUK1@1224|Proteobacteria,1RMX5@1236|Gammaproteobacteria,1XSHS@135623|Vibrionales	135623|Vibrionales	K	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form	cobB	-	-	ko:K12410	-	-	-	-	ko00000,ko01000	-	-	-	SIR2
k141_754_18	1348635.BBJY01000005_gene3202	8.7e-27	104.0	2E51T@1|root,30TP9@2|Bacteria,1QXDV@1224|Proteobacteria,1T39F@1236|Gammaproteobacteria,1XY6F@135623|Vibrionales	135623|Vibrionales	S	Protein of unknown function (DUF3305)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3305
k141_2835_2	675813.VIB_000070	6.61e-90	272.0	COG1011@1|root,COG1011@2|Bacteria,1N0I6@1224|Proteobacteria,1RQ41@1236|Gammaproteobacteria,1XTVY@135623|Vibrionales	135623|Vibrionales	S	hydrolase (HAD superfamily)	-	-	3.1.3.102,3.1.3.104	ko:K20862	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00548,R07280	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HAD_2
k141_272_1	485915.Dret_1483	9.41e-225	630.0	COG1115@1|root,COG1115@2|Bacteria,1MUI3@1224|Proteobacteria,42MG1@68525|delta/epsilon subdivisions,2WKHE@28221|Deltaproteobacteria,2M86Y@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	amino acid carrier protein	-	-	-	ko:K03310	-	-	-	-	ko00000	2.A.25	-	-	Na_Ala_symp
k141_272_2	879212.DespoDRAFT_01361	3.37e-111	328.0	COG0727@1|root,COG0727@2|Bacteria,1R3YG@1224|Proteobacteria,42NM0@68525|delta/epsilon subdivisions,2WM96@28221|Deltaproteobacteria,2MHSQ@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Putative zinc- or iron-chelating domain	-	-	-	ko:K06940	-	-	-	-	ko00000	-	-	-	CxxCxxCC
k141_272_3	1304885.AUEY01000022_gene3385	2.58e-165	472.0	COG0115@1|root,COG0115@2|Bacteria,1MVB0@1224|Proteobacteria,42MKX@68525|delta/epsilon subdivisions,2WJ7X@28221|Deltaproteobacteria,2MIWF@213118|Desulfobacterales	28221|Deltaproteobacteria	E	TIGRFAM branched-chain amino acid aminotransferase	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	iAF987.Gmet_2853	Aminotran_4
k141_272_4	1304885.AUEY01000022_gene3386	2.22e-151	432.0	COG1210@1|root,COG1210@2|Bacteria,1MV5F@1224|Proteobacteria,42MJU@68525|delta/epsilon subdivisions,2WJS4@28221|Deltaproteobacteria,2MHTX@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Nucleotidyl transferase	galU	-	2.7.7.9	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	M00129,M00361,M00362,M00549	R00289	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
k141_3586_1	55601.VANGNB10_cII0884	5.08e-32	120.0	COG0834@1|root,COG0834@2|Bacteria,1RG0M@1224|Proteobacteria,1S4Z3@1236|Gammaproteobacteria	1236|Gammaproteobacteria	ET	Bacterial extracellular solute-binding proteins, family 3	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
k141_3586_2	1348635.BBJY01000010_gene1278	2.01e-21	88.6	COG1846@1|root,COG1846@2|Bacteria,1RH1F@1224|Proteobacteria,1S8WM@1236|Gammaproteobacteria,1XXDE@135623|Vibrionales	135623|Vibrionales	K	COG1846 Transcriptional regulators	ohrR	-	-	-	-	-	-	-	-	-	-	-	MarR
k141_273_1	717774.Marme_3443	1.74e-47	175.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,1XHXU@135619|Oceanospirillales	135619|Oceanospirillales	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k141_3928_1	99598.Cal7507_3469	1.76e-25	112.0	COG0840@1|root,COG0840@2|Bacteria,1GKVK@1117|Cyanobacteria,1HQSN@1161|Nostocales	1117|Cyanobacteria	NT	PFAM Methyl-accepting chemotaxis protein (MCP) signaling domain	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal
k141_2223_1	1167006.UWK_01949	1.13e-13	70.9	COG3829@1|root,COG3829@2|Bacteria,1N1WB@1224|Proteobacteria,42P76@68525|delta/epsilon subdivisions,2WIU6@28221|Deltaproteobacteria,2MIIW@213118|Desulfobacterales	28221|Deltaproteobacteria	KT	Bacterial regulatory protein, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,PAS,PAS_4,PAS_9,Sigma54_activat
k141_2223_2	1121396.KB892924_gene635	2.66e-36	127.0	COG1433@1|root,COG1433@2|Bacteria,1N799@1224|Proteobacteria,42V7X@68525|delta/epsilon subdivisions,2WRG1@28221|Deltaproteobacteria,2MKXV@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Dinitrogenase iron-molybdenum cofactor	-	-	-	-	-	-	-	-	-	-	-	-	Nitro_FeMo-Co
k141_2223_3	335543.Sfum_0651	4.75e-203	586.0	COG4191@1|root,COG4191@2|Bacteria,1R7KQ@1224|Proteobacteria,42PAP@68525|delta/epsilon subdivisions,2WITB@28221|Deltaproteobacteria,2MQZE@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	Cache domain	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,dCache_1
k141_1524_1	55601.VANGNB10_cII0187	7.97e-135	416.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,1RPRH@1236|Gammaproteobacteria,1XSQZ@135623|Vibrionales	135623|Vibrionales	T	COG0642 Signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,Response_reg
k141_3587_1	879212.DespoDRAFT_00232	8.33e-69	216.0	COG0727@1|root,COG0727@2|Bacteria,1REPM@1224|Proteobacteria,42RPZ@68525|delta/epsilon subdivisions,2WNSE@28221|Deltaproteobacteria,2MIBR@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Putative zinc- or iron-chelating domain	-	-	-	-	-	-	-	-	-	-	-	-	CxxCxxCC
k141_1525_1	2423.NA23_0203925	5.83e-09	63.2	COG1220@1|root,COG1220@2|Bacteria,2GC0S@200918|Thermotogae	200918|Thermotogae	O	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis	hslU	-	-	ko:K03667	-	-	-	-	ko00000,ko03110	-	-	-	AAA_2,ClpB_D2-small
k141_4232_1	1348635.BBJY01000017_gene4113	2.79e-90	268.0	COG2917@1|root,COG2917@2|Bacteria,1NWIZ@1224|Proteobacteria,1RQAB@1236|Gammaproteobacteria,1XT4H@135623|Vibrionales	135623|Vibrionales	D	probably involved in intracellular septation	ispZ	-	-	ko:K06190	-	-	-	-	ko00000	-	-	-	IspA
k141_4232_2	675814.VIC_001494	1.86e-239	665.0	COG1301@1|root,COG1301@2|Bacteria,1MU0Q@1224|Proteobacteria,1RMEN@1236|Gammaproteobacteria,1XTN6@135623|Vibrionales	135623|Vibrionales	U	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family	gltP	-	-	-	-	-	-	-	-	-	-	-	SDF
k141_4232_3	675813.VIB_001487	1.29e-137	395.0	COG0159@1|root,COG0159@2|Bacteria,1MXJV@1224|Proteobacteria,1RMGN@1236|Gammaproteobacteria,1XTDE@135623|Vibrionales	135623|Vibrionales	E	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate	trpA	GO:0000162,GO:0003674,GO:0003824,GO:0004834,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.2.1.20	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_syntA
k141_4232_4	1348635.BBJY01000017_gene4116	3.53e-259	713.0	COG0133@1|root,COG0133@2|Bacteria,1MUS8@1224|Proteobacteria,1RP4D@1236|Gammaproteobacteria,1XT49@135623|Vibrionales	135623|Vibrionales	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB	GO:0000162,GO:0003674,GO:0003824,GO:0004834,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.2.1.20	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
k141_4232_5	55601.VANGNB10_cI1022c	3.73e-216	610.0	COG0134@1|root,COG0135@1|root,COG0134@2|Bacteria,COG0135@2|Bacteria,1MW5K@1224|Proteobacteria,1RNYH@1236|Gammaproteobacteria,1XSS7@135623|Vibrionales	135623|Vibrionales	E	Belongs to the TrpC family	trpC	GO:0000162,GO:0003674,GO:0003824,GO:0004425,GO:0004640,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016831,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.1.1.48,5.3.1.24	ko:K13498	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03508,R03509	RC00944,RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPS,PRAI
k141_4232_6	55601.VANGNB10_cI1023c	3.9e-169	480.0	COG0547@1|root,COG0547@2|Bacteria,1MUPV@1224|Proteobacteria,1RNXV@1236|Gammaproteobacteria,1XT64@135623|Vibrionales	135623|Vibrionales	F	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)	trpD	GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.4.2.18	ko:K00766	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R01073	RC00440	ko00000,ko00001,ko00002,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3
k141_4232_7	575788.VS_1967	1.26e-100	296.0	COG0512@1|root,COG0512@2|Bacteria,1RAKJ@1224|Proteobacteria,1RREB@1236|Gammaproteobacteria,1XTCZ@135623|Vibrionales	135623|Vibrionales	EH	COG0512 Anthranilate para-aminobenzoate synthases component II	trpG	GO:0000162,GO:0003674,GO:0003824,GO:0004049,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005950,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016833,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494	4.1.3.27	ko:K01658	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
k141_4232_8	1219065.VPR01S_01_04320	8.11e-268	746.0	COG0147@1|root,COG0147@2|Bacteria,1MVBJ@1224|Proteobacteria,1RMSE@1236|Gammaproteobacteria,1XSGC@135623|Vibrionales	135623|Vibrionales	E	COG0147 Anthranilate para-aminobenzoate synthases component I	trpE	GO:0000162,GO:0003674,GO:0003824,GO:0004049,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005950,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016833,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494	4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
k141_4232_9	1238450.VIBNISOn1_970187	4.11e-136	394.0	COG0613@1|root,COG0613@2|Bacteria,1MWIH@1224|Proteobacteria,1RNCG@1236|Gammaproteobacteria,1XSAZ@135623|Vibrionales	135623|Vibrionales	S	metal-dependent phosphoesterases (PHP family)	trpH	-	3.1.3.97	ko:K07053	-	-	R00188,R11188	RC00078	ko00000,ko01000	-	-	-	PHP
k141_4232_11	158822.LH89_18460	2.41e-126	376.0	COG3866@1|root,COG3866@2|Bacteria,1R9Q3@1224|Proteobacteria,1S3TY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	Pectate lyase	pel	-	4.2.2.2	ko:K01728	ko00040,ko02024,map00040,map02024	-	R02361,R06240	RC00049,RC00705	ko00000,ko00001,ko01000	-	-	-	Pec_lyase_C
k141_4232_14	29495.EA26_15295	2.52e-292	812.0	COG4987@1|root,COG4987@2|Bacteria,1QU1P@1224|Proteobacteria,1RQD7@1236|Gammaproteobacteria,1XUM9@135623|Vibrionales	135623|Vibrionales	CO	COG4987 ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components	cydC	-	-	ko:K16012	ko02010,map02010	-	-	-	ko00000,ko00001,ko02000	3.A.1.129	-	-	ABC_membrane,ABC_tran
k141_4232_15	29495.EA26_15290	2.5e-299	832.0	COG4988@1|root,COG4988@2|Bacteria,1QU1N@1224|Proteobacteria,1RNPI@1236|Gammaproteobacteria,1XUSA@135623|Vibrionales	135623|Vibrionales	CO	COG4988 ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components	cydD	-	-	ko:K16013	ko02010,map02010	-	-	-	ko00000,ko00001,ko02000	3.A.1.129	-	-	ABC_membrane,ABC_tran
k141_4232_16	1219065.VPR01S_01_04170	2.31e-195	545.0	COG0492@1|root,COG0492@2|Bacteria,1MV15@1224|Proteobacteria,1RMEX@1236|Gammaproteobacteria,1XSDE@135623|Vibrionales	135623|Vibrionales	C	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family	trxB	GO:0003674,GO:0003824,GO:0004791,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0042221,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
k141_4232_17	945550.VISI1226_22355	1.04e-130	378.0	2BVTQ@1|root,2Z7J9@2|Bacteria,1P01Z@1224|Proteobacteria,1RNNB@1236|Gammaproteobacteria,1XT57@135623|Vibrionales	135623|Vibrionales	S	Protein of unknown function (DUF2797)	LA2027	-	-	-	-	-	-	-	-	-	-	-	DUF2797
k141_4232_18	675813.VIB_001469	1.91e-99	297.0	COG2949@1|root,COG2949@2|Bacteria,1MURW@1224|Proteobacteria,1RMG7@1236|Gammaproteobacteria,1XSGW@135623|Vibrionales	135623|Vibrionales	S	SanA protein	sanA	-	-	ko:K03748	-	-	-	-	ko00000	-	-	-	DUF218
k141_4232_19	870967.VIS19158_02084	2.26e-41	139.0	2BZ4P@1|root,32Z0A@2|Bacteria,1N883@1224|Proteobacteria,1SD9J@1236|Gammaproteobacteria,1XYPV@135623|Vibrionales	135623|Vibrionales	S	Protein of unknown function (DUF3392)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3392
k141_4232_21	1517681.HW45_24270	1.86e-17	80.1	2AWAE@1|root,31N5Y@2|Bacteria,1QJXB@1224|Proteobacteria,1THZD@1236|Gammaproteobacteria,1XXZU@135623|Vibrionales	135623|Vibrionales	D	Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1 1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division	-	-	-	ko:K13053	-	-	-	-	ko00000,ko03036	-	-	-	SulA
k141_4232_22	55601.VANGNB10_cI1571	2.11e-30	125.0	COG0790@1|root,COG2214@1|root,COG0790@2|Bacteria,COG2214@2|Bacteria,1NMS9@1224|Proteobacteria,1SJF3@1236|Gammaproteobacteria,1XVUZ@135623|Vibrionales	135623|Vibrionales	O	DnaJ molecular chaperone homology domain	-	-	-	ko:K07126	-	-	-	-	ko00000	-	-	-	Sel1
k141_4232_23	243277.VC_1195	2.93e-104	307.0	COG2885@1|root,COG2885@2|Bacteria,1MYBP@1224|Proteobacteria,1RVRF@1236|Gammaproteobacteria,1XW50@135623|Vibrionales	135623|Vibrionales	M	Belongs to the ompA family	yiaD	-	-	-	-	-	-	-	-	-	-	-	Gly-zipper_Omp,OmpA
k141_4232_24	675813.VIB_001462	8.83e-143	405.0	2CPPK@1|root,32SJJ@2|Bacteria,1MZQ2@1224|Proteobacteria,1SABH@1236|Gammaproteobacteria,1XU68@135623|Vibrionales	135623|Vibrionales	S	Protein of unknown function (DUF2786)	VV12383	-	-	-	-	-	-	-	-	-	-	-	DUF2786
k141_2225_1	945550.VISI1226_07562	1.57e-66	208.0	COG2823@1|root,COG2823@2|Bacteria,1MUZ2@1224|Proteobacteria,1RY2B@1236|Gammaproteobacteria,1XVEM@135623|Vibrionales	135623|Vibrionales	S	periplasmic or secreted lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	BON
k141_1908_1	1121396.KB892901_gene2208	7.21e-184	521.0	COG1148@1|root,COG1148@2|Bacteria,1Q0ZF@1224|Proteobacteria,42NHH@68525|delta/epsilon subdivisions,2WJ6M@28221|Deltaproteobacteria,2MIS1@213118|Desulfobacterales	28221|Deltaproteobacteria	C	FAD dependent oxidoreductase	qmoA	-	-	ko:K16885	-	-	-	-	ko00000	-	-	-	FAD_oxidored,NAD_binding_8,Pyr_redox_2
k141_1908_2	1304885.AUEY01000017_gene3747	0.0	1146.0	COG1148@1|root,COG1908@1|root,COG1148@2|Bacteria,COG1908@2|Bacteria,1MWAG@1224|Proteobacteria,42NNE@68525|delta/epsilon subdivisions,2WJZX@28221|Deltaproteobacteria,2MI6X@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Methyl-viologen-reducing hydrogenase, delta subunit	qmoB	-	-	ko:K16886	-	-	-	-	ko00000	-	-	-	Fer4,Fer4_9,FlpD,Pyr_redox_2
k141_1908_3	96561.Dole_1001	9.52e-163	469.0	COG1150@1|root,COG1150@2|Bacteria,1QUKA@1224|Proteobacteria,42MNE@68525|delta/epsilon subdivisions,2WIN3@28221|Deltaproteobacteria,2MHSC@213118|Desulfobacterales	28221|Deltaproteobacteria	C	4Fe-4S dicluster domain	qmoC	-	-	ko:K16887	-	-	-	-	ko00000	-	-	-	Fer4_17,Fer4_8,Fer4_9,Nitrate_red_gam
k141_1908_4	1224746.B932_3174	5.65e-33	131.0	COG1262@1|root,COG1262@2|Bacteria,1MZ25@1224|Proteobacteria,2TRJH@28211|Alphaproteobacteria,2JZAC@204441|Rhodospirillales	204441|Rhodospirillales	S	Sulfatase-modifying factor enzyme 1	-	-	-	ko:K20333	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	FGE-sulfatase
k141_3588_1	1265505.ATUG01000001_gene3314	1.78e-27	110.0	COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,42MK4@68525|delta/epsilon subdivisions,2WJJ8@28221|Deltaproteobacteria,2MIII@213118|Desulfobacterales	28221|Deltaproteobacteria	G	Tripartite ATP-independent periplasmic transporter, DctM component	-	-	-	-	-	-	-	-	-	-	-	-	DctM
k141_3588_2	1121382.JQKG01000054_gene2130	4.58e-40	140.0	COG4675@1|root,COG4675@2|Bacteria	2|Bacteria	M	tail collar domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Collar
k141_3588_3	1121378.KB899721_gene304	2.19e-09	59.3	COG4675@1|root,COG4675@2|Bacteria	2|Bacteria	M	tail collar domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Collar
k141_1527_1	1232437.KL661978_gene3868	5.53e-25	103.0	COG0210@1|root,COG1379@1|root,COG0210@2|Bacteria,COG1379@2|Bacteria,1MU0G@1224|Proteobacteria,42MKU@68525|delta/epsilon subdivisions,2WJR3@28221|Deltaproteobacteria,2MIS3@213118|Desulfobacterales	28221|Deltaproteobacteria	L	PFAM UvrD REP helicase	-	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
k141_1527_2	177437.HRM2_49440	8.08e-57	185.0	COG2974@1|root,COG2974@2|Bacteria,1N4GC@1224|Proteobacteria,42RPT@68525|delta/epsilon subdivisions,2WQUM@28221|Deltaproteobacteria,2MJSD@213118|Desulfobacterales	28221|Deltaproteobacteria	L	Putative exonuclease, RdgC	-	-	-	-	-	-	-	-	-	-	-	-	RdgC
k141_1527_3	1121405.dsmv_3100	8.08e-11	60.8	COG2974@1|root,COG2974@2|Bacteria,1RCUH@1224|Proteobacteria,42QVW@68525|delta/epsilon subdivisions,2WN5B@28221|Deltaproteobacteria,2MJPM@213118|Desulfobacterales	28221|Deltaproteobacteria	L	May be involved in recombination	-	-	-	-	-	-	-	-	-	-	-	-	RdgC
k141_274_1	1265505.ATUG01000001_gene4375	1.33e-71	224.0	COG1946@1|root,COG1946@2|Bacteria,1MV9R@1224|Proteobacteria,42NB1@68525|delta/epsilon subdivisions,2WM1K@28221|Deltaproteobacteria,2MJ0B@213118|Desulfobacterales	28221|Deltaproteobacteria	I	acyl-CoA thioesterase II	tesB	-	-	ko:K10805	ko01040,map01040	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	4HBT_3
k141_1528_1	96561.Dole_1899	6.35e-77	245.0	COG3209@1|root,COG3209@2|Bacteria,1MVV1@1224|Proteobacteria,42MK6@68525|delta/epsilon subdivisions,2WKN2@28221|Deltaproteobacteria,2MIC4@213118|Desulfobacterales	28221|Deltaproteobacteria	M	RHS protein	-	-	-	-	-	-	-	-	-	-	-	-	RHS,RHS_repeat
k141_3929_1	1379281.AVAG01000046_gene322	0.0	1519.0	COG1038@1|root,COG1038@2|Bacteria,1NW9R@1224|Proteobacteria,43BKE@68525|delta/epsilon subdivisions,2X6YE@28221|Deltaproteobacteria,2M8M5@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	Carbamoyl-phosphate synthetase large chain domain protein	-	-	6.4.1.1	ko:K01958	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	M00173	R00344	RC00040,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2,HMGL-like,PYC_OADA
k141_3589_1	1005995.GTPT_0831	1.16e-37	145.0	COG2267@1|root,COG2267@2|Bacteria,1MWDA@1224|Proteobacteria,1RRJP@1236|Gammaproteobacteria,4BVIT@82986|Tatumella	1236|Gammaproteobacteria	I	alpha/beta hydrolase fold	pldB	GO:0003674,GO:0003824,GO:0004620,GO:0004622,GO:0005575,GO:0005623,GO:0005886,GO:0006629,GO:0008150,GO:0008152,GO:0016020,GO:0016298,GO:0016740,GO:0016746,GO:0016747,GO:0016787,GO:0016788,GO:0044238,GO:0044464,GO:0052689,GO:0071704,GO:0071944	3.1.1.5	ko:K01048	ko00564,map00564	-	-	-	ko00000,ko00001,ko01000	-	-	iETEC_1333.ETEC_4102,iEcHS_1320.EcHS_A4049	Hydrolase_4
k141_2499_1	1121396.KB893097_gene4345	3.63e-51	172.0	COG0850@1|root,COG0850@2|Bacteria,1RGMT@1224|Proteobacteria,42QN6@68525|delta/epsilon subdivisions,2WM3X@28221|Deltaproteobacteria,2MJ73@213118|Desulfobacterales	28221|Deltaproteobacteria	D	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization	minC	-	-	ko:K03610	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	MinC_C
k141_2499_2	1121405.dsmv_3125	1.07e-123	360.0	COG2894@1|root,COG2894@2|Bacteria,1MUEU@1224|Proteobacteria,42QAW@68525|delta/epsilon subdivisions,2WIXS@28221|Deltaproteobacteria,2MIY5@213118|Desulfobacterales	28221|Deltaproteobacteria	D	Belongs to the ParA family	minD	-	-	ko:K03609	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31,CbiA
k141_2499_3	1121405.dsmv_3126	3.16e-34	119.0	COG0851@1|root,COG0851@2|Bacteria,1N0Z7@1224|Proteobacteria,42TYJ@68525|delta/epsilon subdivisions,2WQAJ@28221|Deltaproteobacteria,2MKG6@213118|Desulfobacterales	28221|Deltaproteobacteria	D	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell	minE	-	-	ko:K03608	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	MinE
k141_2499_4	96561.Dole_0406	2.42e-53	182.0	2BV42@1|root,32QH6@2|Bacteria,1MZ0Q@1224|Proteobacteria,42T0A@68525|delta/epsilon subdivisions,2WP4M@28221|Deltaproteobacteria,2MN8V@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_2499_5	555779.Dthio_PD2530	1.63e-60	198.0	COG1418@1|root,COG1418@2|Bacteria,1RGCM@1224|Proteobacteria,42RC5@68525|delta/epsilon subdivisions,2WNBA@28221|Deltaproteobacteria,2MBBU@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	mRNA catabolic process	-	-	-	-	-	-	-	-	-	-	-	-	HD
k141_2499_6	192952.MM_2090	3.05e-20	88.2	COG1342@1|root,arCOG02238@2157|Archaea,2Y002@28890|Euryarchaeota,2NBJ0@224756|Methanomicrobia	224756|Methanomicrobia	S	Protein of unknown function  DUF134	-	-	-	ko:K06933	-	-	-	-	ko00000	-	-	-	DUF134
k141_2499_7	1123371.ATXH01000024_gene1016	3.42e-15	77.0	COG1433@1|root,COG1433@2|Bacteria,2GI3A@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	S	Dinitrogenase iron-molybdenum cofactor	-	-	-	-	-	-	-	-	-	-	-	-	Nitro_FeMo-Co
k141_2499_8	1565314.OA34_00895	1.39e-68	221.0	COG1149@1|root,COG1149@2|Bacteria,1NCD9@1224|Proteobacteria,42PHV@68525|delta/epsilon subdivisions	1224|Proteobacteria	C	Cobyrinic acid a,c-diamide synthase	-	-	-	-	-	-	-	-	-	-	-	-	CbiA,Fer4
k141_2499_9	1121403.AUCV01000003_gene1751	2.38e-69	224.0	COG1149@1|root,COG1149@2|Bacteria,1MVPB@1224|Proteobacteria,42MJ5@68525|delta/epsilon subdivisions,2WJ9M@28221|Deltaproteobacteria,2MIKP@213118|Desulfobacterales	28221|Deltaproteobacteria	C	CobQ CobB MinD ParA nucleotide binding domain	-	-	-	-	-	-	-	-	-	-	-	-	CbiA,Fer4
k141_3930_1	519441.Smon_0291	7.82e-13	70.1	COG1494@1|root,COG1494@2|Bacteria,3796W@32066|Fusobacteria	32066|Fusobacteria	G	Bacterial fructose-1,6-bisphosphatase, glpX-encoded	glpX	-	3.1.3.11	ko:K02446	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00165,M00167	R00762,R04780	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FBPase_glpX
k141_1910_2	675812.VHA_001463	6.29e-174	492.0	COG0583@1|root,COG0583@2|Bacteria,1NG7S@1224|Proteobacteria,1SKYZ@1236|Gammaproteobacteria,1XW4U@135623|Vibrionales	135623|Vibrionales	K	Bacterial regulatory helix-turn-helix protein, lysR family	-	-	-	ko:K13634	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,LysR_substrate
k141_559_2	391615.ABSJ01000027_gene215	6.8e-40	147.0	COG0610@1|root,COG0610@2|Bacteria,1MU96@1224|Proteobacteria,1RP2Q@1236|Gammaproteobacteria,1J550@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	V	Subunit R is required for both nuclease and ATPase activities, but not for modification	-	-	3.1.21.3	ko:K01153	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HSDR_N,ResIII
k141_559_5	675814.VIC_001232	1.22e-173	491.0	2DEJ7@1|root,2ZN6S@2|Bacteria,1Q8ZU@1224|Proteobacteria,1TJW9@1236|Gammaproteobacteria,1Y1S2@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_559_6	675814.VIC_001231	1.78e-256	711.0	COG3209@1|root,COG3209@2|Bacteria,1PAAV@1224|Proteobacteria,1SVCU@1236|Gammaproteobacteria,1Y21E@135623|Vibrionales	135623|Vibrionales	M	COG3209 Rhs family protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_559_8	675814.VIC_001229	0.0	1234.0	COG0507@1|root,COG0550@1|root,COG1112@1|root,COG0507@2|Bacteria,COG0550@2|Bacteria,COG1112@2|Bacteria,1N8SW@1224|Proteobacteria,1SN1Z@1236|Gammaproteobacteria,1XXPT@135623|Vibrionales	135623|Vibrionales	L	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_11,AAA_12,PLDc_2,Toprim
k141_2226_1	1219065.VPR01S_01_02500	2.76e-09	53.9	2AWX4@1|root,31NUN@2|Bacteria,1QKIA@1224|Proteobacteria,1TINI@1236|Gammaproteobacteria,1XZDH@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_2226_2	1348635.BBJY01000005_gene3264	1.58e-58	192.0	2AX9W@1|root,31P8X@2|Bacteria,1QJEF@1224|Proteobacteria,1THDS@1236|Gammaproteobacteria,1XUGM@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_2226_3	1348635.BBJY01000005_gene3172	3.5e-170	482.0	COG0039@1|root,COG0039@2|Bacteria,1MV57@1224|Proteobacteria,1RPAX@1236|Gammaproteobacteria,1XWBX@135623|Vibrionales	135623|Vibrionales	C	Belongs to the LDH MDH superfamily	-	-	1.1.1.27	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	-	R00703,R01000,R03104	RC00031,RC00044	ko00000,ko00001,ko01000,ko04147	-	-	-	Ldh_1_C,Ldh_1_N
k141_2226_4	1001530.BACE01000027_gene907	8.67e-28	109.0	COG3883@1|root,COG3883@2|Bacteria,1MVIJ@1224|Proteobacteria,1RYAJ@1236|Gammaproteobacteria,1Y334@135623|Vibrionales	135623|Vibrionales	S	Protein of unknown function (DUF3450)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3450
k141_560_1	55601.VANGNB10_cI1821c	5.84e-99	298.0	COG1940@1|root,COG1940@2|Bacteria,1MX6M@1224|Proteobacteria,1RNZ1@1236|Gammaproteobacteria,1XTAB@135623|Vibrionales	135623|Vibrionales	GK	COG1940 Transcriptional regulator sugar kinase	mlc	-	-	ko:K15545	-	-	-	-	ko00000,ko03000	-	-	-	ROK
k141_4638_1	55601.VANGNB10_cI0643c	1.35e-144	425.0	COG0248@1|root,COG0248@2|Bacteria,1MV35@1224|Proteobacteria,1RN3V@1236|Gammaproteobacteria,1XTUA@135623|Vibrionales	135623|Vibrionales	FP	Belongs to the GppA Ppx family	ppx	GO:0003674,GO:0003824,GO:0004309,GO:0006082,GO:0006793,GO:0006797,GO:0006798,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0071704,GO:1901575	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	Ppx-GppA
k141_4638_2	675815.VOA_000873	2.06e-155	444.0	COG0226@1|root,COG0226@2|Bacteria,1MVXP@1224|Proteobacteria,1RQDH@1236|Gammaproteobacteria,1XTH3@135623|Vibrionales	135623|Vibrionales	P	Phosphate ABC transporter, periplasmic phosphate-binding protein	-	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
k141_4638_3	1187848.AJYQ01000069_gene2618	9.49e-271	746.0	COG5002@1|root,COG5002@2|Bacteria,1MWF3@1224|Proteobacteria,1RN0F@1236|Gammaproteobacteria,1XSR8@135623|Vibrionales	135623|Vibrionales	T	Phosphate regulon sensor protein	phoR	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF3329,HATPase_c,HisKA,PAS
k141_4638_4	29495.EA26_03720	1.33e-156	440.0	COG0745@1|root,COG0745@2|Bacteria,1MY2Z@1224|Proteobacteria,1RN41@1236|Gammaproteobacteria,1XU4T@135623|Vibrionales	135623|Vibrionales	K	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	phoB	-	-	ko:K07657	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
k141_4638_5	675815.VOA_000876	3.93e-163	462.0	COG2974@1|root,COG2974@2|Bacteria,1MXPR@1224|Proteobacteria,1RMNN@1236|Gammaproteobacteria,1XT7H@135623|Vibrionales	135623|Vibrionales	L	May be involved in recombination	rdgC	-	-	ko:K03554	-	-	-	-	ko00000,ko03400	-	-	-	RdgC
k141_4638_7	945550.VISI1226_15456	3.81e-50	159.0	COG1145@1|root,COG1145@2|Bacteria,1MZ6H@1224|Proteobacteria,1S8ZV@1236|Gammaproteobacteria,1XYGZ@135623|Vibrionales	135623|Vibrionales	C	COG1145 Ferredoxin	yfhL	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_7
k141_4638_8	796620.VIBC2010_09882	1.01e-115	337.0	COG0778@1|root,COG0778@2|Bacteria,1NIJ8@1224|Proteobacteria,1RMRT@1236|Gammaproteobacteria,1XTEA@135623|Vibrionales	135623|Vibrionales	C	NAD(P)h-flavin oxidoreductase	nfsA	-	1.5.1.38	ko:K10678,ko:K19285	ko00633,ko00740,ko01100,ko01120,map00633,map00740,map01100,map01120	-	R05706,R08014,R08017,R08042	RC00126,RC00250	ko00000,ko00001,ko01000	-	-	-	Nitroreductase
k141_3592_1	28072.Nos7524_3293	2.45e-32	128.0	COG2207@1|root,COG2207@2|Bacteria,1G43F@1117|Cyanobacteria	1117|Cyanobacteria	K	COGs COG2207 AraC-type DNA-binding domain-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
k141_2500_1	96561.Dole_2098	7.74e-86	261.0	COG1489@1|root,COG1489@2|Bacteria,1MUC3@1224|Proteobacteria,42QXT@68525|delta/epsilon subdivisions,2WN0R@28221|Deltaproteobacteria,2MJ9Y@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Belongs to the SfsA family	sfsA	-	-	ko:K06206	-	-	-	-	ko00000	-	-	-	SfsA
k141_2500_2	439235.Dalk_2376	3.02e-27	111.0	COG1413@1|root,COG1413@2|Bacteria,1R6G4@1224|Proteobacteria,42T2X@68525|delta/epsilon subdivisions,2WPNC@28221|Deltaproteobacteria,2MKIT@213118|Desulfobacterales	28221|Deltaproteobacteria	C	lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,HEAT_EZ
k141_1912_2	1286171.EAL2_c10400	4.18e-102	318.0	COG0275@1|root,COG0682@1|root,COG0275@2|Bacteria,COG0682@2|Bacteria,1TNZV@1239|Firmicutes,248B5@186801|Clostridia,25UQQ@186806|Eubacteriaceae	186801|Clostridia	J	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH	-	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
k141_1912_3	177437.HRM2_12620	8.54e-39	135.0	COG2001@1|root,COG2001@2|Bacteria,1RHCG@1224|Proteobacteria,42TRZ@68525|delta/epsilon subdivisions,2WQRI@28221|Deltaproteobacteria,2MKIW@213118|Desulfobacterales	28221|Deltaproteobacteria	K	Belongs to the MraZ family	mraZ	GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141	-	ko:K03925	-	-	-	-	ko00000	-	-	-	MraZ
k141_576_2	1232437.KL661988_gene48	2.51e-09	60.1	2CDF3@1|root,32TZK@2|Bacteria,1N1D0@1224|Proteobacteria,42UJW@68525|delta/epsilon subdivisions,2WQ5K@28221|Deltaproteobacteria,2MKQS@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_2518_1	529507.PMI1594	3.92e-23	99.8	2CJ77@1|root,31WMU@2|Bacteria,1QCU8@1224|Proteobacteria,1T8ME@1236|Gammaproteobacteria,3Z34M@583|Proteus	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_1621_3	926551.KB900715_gene2222	3.91e-63	206.0	COG0738@1|root,COG0738@2|Bacteria,4NEYR@976|Bacteroidetes,1HY8N@117743|Flavobacteriia,1ERK7@1016|Capnocytophaga	976|Bacteroidetes	G	Psort location CytoplasmicMembrane, score 10.00	fucP	-	-	ko:K02429	-	-	-	-	ko00000,ko02000	2.A.1.7	-	-	MFS_1
k141_1622_1	1111728.ATYS01000075_gene3516	6.11e-53	188.0	COG0068@1|root,COG0068@2|Bacteria,1MVP8@1224|Proteobacteria,1RP08@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide	hypF	GO:0003674,GO:0003824,GO:0005488,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009987,GO:0010467,GO:0016740,GO:0016741,GO:0016743,GO:0019538,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0046872,GO:0046914,GO:0046944,GO:0051604,GO:0071704,GO:1901564	-	ko:K04656	-	-	-	-	ko00000	-	-	-	Acylphosphatase,Sua5_yciO_yrdC,zf-HYPF
k141_4051_1	243277.VC_1152	1.28e-100	303.0	COG1639@1|root,COG1639@2|Bacteria,1N7EN@1224|Proteobacteria,1RT8G@1236|Gammaproteobacteria,1XUWE@135623|Vibrionales	135623|Vibrionales	T	Signal transduction protein	-	-	-	-	-	-	-	-	-	-	-	-	HDOD
k141_4051_2	1517681.HW45_24145	4.65e-37	134.0	COG3070@1|root,COG3070@2|Bacteria,1QJGH@1224|Proteobacteria,1THG9@1236|Gammaproteobacteria,1XVKC@135623|Vibrionales	135623|Vibrionales	K	COG3070 Regulator of competence-specific genes	VV1446	GO:0006810,GO:0007154,GO:0008150,GO:0009290,GO:0009292,GO:0009294,GO:0009605,GO:0009987,GO:0009991,GO:0015931,GO:0030420,GO:0031668,GO:0044764,GO:0050657,GO:0050896,GO:0051027,GO:0051179,GO:0051234,GO:0051704,GO:0051716,GO:0071496,GO:0071702,GO:0071705,GO:0098657	-	ko:K07343	-	-	-	-	ko00000	-	-	-	TfoX_C,TfoX_N
k141_4051_3	1219065.VPR01S_01_04570	5.13e-88	264.0	2B0QJ@1|root,31T2K@2|Bacteria,1QJDY@1224|Proteobacteria,1THD8@1236|Gammaproteobacteria,1XU73@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_4051_4	1051646.VITU9109_23435	2.65e-68	211.0	COG0784@1|root,COG0784@2|Bacteria,1MYIP@1224|Proteobacteria,1S89X@1236|Gammaproteobacteria,1XWV8@135623|Vibrionales	135623|Vibrionales	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
k141_4051_5	55601.VANGNB10_cI1057c	1.96e-246	701.0	COG0664@1|root,COG0784@1|root,COG4191@1|root,COG0664@2|Bacteria,COG0784@2|Bacteria,COG4191@2|Bacteria,1R97I@1224|Proteobacteria,1RNJ8@1236|Gammaproteobacteria,1XSZK@135623|Vibrionales	135623|Vibrionales	T	COG0642 Signal transduction histidine kinase	VP1245	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg,cNMP_binding
k141_4051_6	870967.VIS19158_17261	3.17e-40	151.0	COG5339@1|root,COG5339@2|Bacteria,1N902@1224|Proteobacteria,1SDR2@1236|Gammaproteobacteria,1XSXF@135623|Vibrionales	135623|Vibrionales	S	Bacterial protein of unknown function (DUF945)	-	-	-	-	-	-	-	-	-	-	-	-	DUF945
k141_5078_1	1304888.ATWF01000001_gene914	9e-216	621.0	COG0488@1|root,COG0488@2|Bacteria,2GFC2@200930|Deferribacteres	200930|Deferribacteres	S	ABC transporter	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_Xtn
k141_5078_2	1304885.AUEY01000101_gene2140	0.0	1268.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1MU0R@1224|Proteobacteria,42NDJ@68525|delta/epsilon subdivisions,2WJSH@28221|Deltaproteobacteria,2MIZ3@213118|Desulfobacterales	28221|Deltaproteobacteria	G	Belongs to the PEP-utilizing enzyme family	ppdK	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
k141_5078_3	706587.Desti_4582	8.75e-66	203.0	COG2030@1|root,COG2030@2|Bacteria,1MWPK@1224|Proteobacteria,42SWX@68525|delta/epsilon subdivisions,2WPJ0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	dehydratase	maoC	-	4.2.1.55	ko:K17865	ko00630,ko00650,ko01120,ko01200,map00630,map00650,map01120,map01200	M00373	R03027	RC00831	ko00000,ko00001,ko00002,ko01000	-	-	-	MaoC_dehydratas
k141_5078_4	1304885.AUEY01000094_gene3533	1.49e-191	543.0	COG3243@1|root,COG3243@2|Bacteria,1MU68@1224|Proteobacteria,42MW8@68525|delta/epsilon subdivisions,2WKI6@28221|Deltaproteobacteria,2MIK1@213118|Desulfobacterales	28221|Deltaproteobacteria	I	Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus	phaC	-	-	ko:K03821	ko00650,map00650	-	R04254	RC00004	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1
k141_5078_5	1304885.AUEY01000094_gene3534	5.98e-61	202.0	28KIX@1|root,2ZA44@2|Bacteria,1Q0JI@1224|Proteobacteria,42SSY@68525|delta/epsilon subdivisions,2WPVQ@28221|Deltaproteobacteria,2MK98@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Poly(R)-hydroxyalkanoic acid synthase subunit (PHA_synth_III_E)	-	-	-	-	-	-	-	-	-	-	-	-	PHA_synth_III_E
k141_4052_1	1123274.KB899416_gene2549	6.81e-122	363.0	COG0369@1|root,COG1151@2|Bacteria,2J5J3@203691|Spirochaetes	203691|Spirochaetes	C	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O	hcp	-	1.7.99.1	ko:K05601	ko00910,map00910	-	R00143	RC02797	ko00000,ko00001,ko01000	-	-	-	DUF1858,Prismane
k141_4052_2	269799.Gmet_2920	5.43e-118	372.0	28J7E@1|root,2Z92U@2|Bacteria,1NAE1@1224|Proteobacteria,42P08@68525|delta/epsilon subdivisions,2WJXV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4105)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4105
k141_4052_3	96561.Dole_2383	2.63e-59	188.0	2DMP9@1|root,32SV1@2|Bacteria,1N17Y@1224|Proteobacteria,42TQF@68525|delta/epsilon subdivisions,2WQHJ@28221|Deltaproteobacteria,2MKRY@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF3015)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3015
k141_5079_1	251229.Chro_3664	4.87e-240	724.0	COG1020@1|root,COG1020@2|Bacteria	2|Bacteria	Q	D-alanine [D-alanyl carrier protein] ligase activity	-	-	-	ko:K12240	ko01053,map01053	-	-	-	ko00000,ko00001,ko01008	-	-	-	AMP-binding,AMP-binding_C,Condensation,Nitroreductase,PP-binding,Thioesterase
k141_5080_1	243277.VC_1547	1.04e-16	83.2	COG0811@1|root,COG0811@2|Bacteria,1QNJ1@1224|Proteobacteria,1RQWT@1236|Gammaproteobacteria,1XSJP@135623|Vibrionales	135623|Vibrionales	U	COG0811 Biopolymer transport proteins	-	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
k141_5080_2	298386.PBPRB1221	1.25e-11	65.5	COG3883@1|root,COG3883@2|Bacteria,1MVIJ@1224|Proteobacteria,1RYAJ@1236|Gammaproteobacteria,1Y334@135623|Vibrionales	135623|Vibrionales	S	Protein of unknown function (DUF3450)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3450
k141_5081_1	1121459.AQXE01000011_gene2414	1.08e-87	263.0	COG0655@1|root,COG0655@2|Bacteria,1RAK6@1224|Proteobacteria,42QS5@68525|delta/epsilon subdivisions,2WN2M@28221|Deltaproteobacteria,2M7SB@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	PFAM NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
k141_5082_1	1218086.BBNB01000010_gene842	3.36e-18	86.7	COG1494@1|root,COG1494@2|Bacteria,1R5BK@1224|Proteobacteria,1S16G@1236|Gammaproteobacteria,3WWIC@544|Citrobacter	1236|Gammaproteobacteria	G	Bacterial fructose-1,6-bisphosphatase, glpX-encoded	yggF	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0019318,GO:0019319,GO:0019637,GO:0030145,GO:0030388,GO:0042132,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0046872,GO:0046914,GO:0050308,GO:0071704,GO:1901135,GO:1901576	-	-	-	-	-	-	-	-	-	iSF_1195.SF2920,iUMNK88_1353.UMNK88_3626	FBPase_glpX
k141_5082_3	1454202.PPBDW_60030___1	8.08e-40	134.0	COG3924@1|root,COG3924@2|Bacteria,1MZ8K@1224|Proteobacteria,1S8QV@1236|Gammaproteobacteria,1XYCH@135623|Vibrionales	135623|Vibrionales	S	Protein of unknown function (DUF997)	-	-	-	-	-	-	-	-	-	-	-	-	DUF997
k141_4053_3	345073.VC395_2221	3.01e-191	536.0	COG0136@1|root,COG0136@2|Bacteria,1MUHG@1224|Proteobacteria,1RNB6@1236|Gammaproteobacteria,1XT9P@135623|Vibrionales	135623|Vibrionales	E	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate	asd	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004073,GO:0006082,GO:0006520,GO:0006549,GO:0006553,GO:0006555,GO:0006566,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009081,GO:0009082,GO:0009085,GO:0009086,GO:0009088,GO:0009089,GO:0009097,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
k141_4053_4	55601.VANGNB10_cI1916c	4.41e-201	565.0	COG0111@1|root,COG0111@2|Bacteria,1N5TD@1224|Proteobacteria,1RMFW@1236|Gammaproteobacteria,1XSPZ@135623|Vibrionales	135623|Vibrionales	H	Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate	pdxB	GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	1.1.1.290	ko:K03473	ko00750,ko01100,map00750,map01100	M00124	R04210	RC00084	ko00000,ko00001,ko00002,ko01000	-	-	-	2-Hacid_dh,2-Hacid_dh_C,DUF3410
k141_4053_6	672.VV93_v1c21330	2.21e-45	161.0	COG0665@1|root,COG4121@1|root,COG0665@2|Bacteria,COG4121@2|Bacteria,1MZW5@1224|Proteobacteria,1RMTE@1236|Gammaproteobacteria,1XSRW@135623|Vibrionales	135623|Vibrionales	J	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34	mnmC	GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0003824,GO:0004808,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016491,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0055114,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.1.1.61	ko:K15461	-	-	R00601,R08702	RC00003,RC00053,RC00060,RC01483	ko00000,ko01000,ko03016	-	-	-	DAO,Methyltransf_30
k141_5083_1	1121406.JAEX01000002_gene895	1.33e-16	84.3	COG4191@1|root,COG4585@1|root,COG4191@2|Bacteria,COG4585@2|Bacteria,1MWPN@1224|Proteobacteria,42U4X@68525|delta/epsilon subdivisions,2WQCD@28221|Deltaproteobacteria,2MA4N@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3,PAS_3,PAS_9
k141_4054_1	871968.DESME_08240	4.39e-13	78.6	COG5001@1|root,COG5001@2|Bacteria,1TP8V@1239|Firmicutes,247PX@186801|Clostridia,26021@186807|Peptococcaceae	186801|Clostridia	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_4,PAS_9
k141_5084_1	237368.SCABRO_03313	3.48e-66	217.0	COG0469@1|root,COG0469@2|Bacteria,2IY60@203682|Planctomycetes	203682|Planctomycetes	G	Belongs to the pyruvate kinase family	-	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PK,PK_C
k141_5084_2	65093.PCC7418_0450	7.09e-44	156.0	COG0126@1|root,COG0126@2|Bacteria,1G2FM@1117|Cyanobacteria	1117|Cyanobacteria	F	Belongs to the phosphoglycerate kinase family	pgk	-	2.7.2.3	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01512	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
k141_5085_1	1348635.BBJY01000001_gene2375	1.14e-06	47.0	COG2914@1|root,COG2914@2|Bacteria,1QSGK@1224|Proteobacteria,1RVWI@1236|Gammaproteobacteria,1Y1GZ@135623|Vibrionales	135623|Vibrionales	S	RnfH family Ubiquitin	-	-	-	ko:K09801	-	-	-	-	ko00000	-	-	-	Ub-RnfH
k141_5085_2	1348635.BBJY01000001_gene2376	5.5e-86	259.0	COG4660@1|root,COG4660@2|Bacteria,1MW6N@1224|Proteobacteria,1RMEH@1236|Gammaproteobacteria,1Y030@135623|Vibrionales	135623|Vibrionales	C	Rnf-Nqr subunit, membrane protein	-	-	-	ko:K03613	-	-	-	-	ko00000	-	-	-	Rnf-Nqr
k141_5086_1	641491.DND132_1728	2.09e-61	201.0	COG0616@1|root,COG0616@2|Bacteria,1MUXE@1224|Proteobacteria,42QUN@68525|delta/epsilon subdivisions,2WN6Q@28221|Deltaproteobacteria,2M8B2@213115|Desulfovibrionales	28221|Deltaproteobacteria	OU	TIGRFAM signal peptide peptidase SppA, 36K type	sppA2	-	-	ko:K04773	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S49
k141_4055_1	566466.NOR53_3566	2.03e-82	270.0	COG3666@1|root,COG3666@2|Bacteria,1N3QR@1224|Proteobacteria,1S01K@1236|Gammaproteobacteria,1J7W3@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	L	L COG3666 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_6,DUF772
k141_5089_1	1125863.JAFN01000001_gene1191	1.22e-14	81.6	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42KZR@68525|delta/epsilon subdivisions,2WJ2T@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	histidine kinase HAMP region domain protein	mcp40H-5	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal,dCache_2,sCache_2
k141_5090_1	223926.28806906	1.5e-64	202.0	COG0491@1|root,COG0491@2|Bacteria,1MUDN@1224|Proteobacteria,1RMMG@1236|Gammaproteobacteria,1XU1B@135623|Vibrionales	135623|Vibrionales	S	COG0491 Zn-dependent hydrolases, including glyoxylases	ycbL	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
k141_5090_2	1348635.BBJY01000015_gene736	1.02e-62	196.0	COG0807@1|root,COG0807@2|Bacteria,1MWZR@1224|Proteobacteria,1RMFX@1236|Gammaproteobacteria,1XU21@135623|Vibrionales	135623|Vibrionales	F	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate	ribA	GO:0003674,GO:0003824,GO:0003933,GO:0003935,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017144,GO:0018130,GO:0019238,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	3.5.4.25	ko:K01497	ko00740,ko00790,ko01100,ko01110,ko02024,map00740,map00790,map01100,map01110,map02024	M00125	R00425	RC00293,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_cyclohydro2
k141_5091_1	1121403.AUCV01000005_gene349	2.64e-137	398.0	COG1454@1|root,COG1454@2|Bacteria,1MVPH@1224|Proteobacteria,42NQF@68525|delta/epsilon subdivisions,2WKU3@28221|Deltaproteobacteria,2MIS8@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM Iron-containing alcohol dehydrogenase	-	-	1.1.3.48	ko:K19714	-	-	R11394	RC03427	ko00000,ko01000,ko01005	-	-	-	Fe-ADH
k141_1628_1	1121448.DGI_2438	1.18e-120	381.0	COG1352@1|root,COG2201@1|root,COG5000@1|root,COG1352@2|Bacteria,COG2201@2|Bacteria,COG5000@2|Bacteria,1NU7E@1224|Proteobacteria,43DD7@68525|delta/epsilon subdivisions,2X8J6@28221|Deltaproteobacteria,2MHIH@213115|Desulfovibrionales	28221|Deltaproteobacteria	NT	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	-	-	2.1.1.80,3.1.1.61	ko:K13924	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	PAS_4,PAS_9
k141_1628_2	525897.Dbac_2135	1.93e-210	600.0	COG0578@1|root,COG0578@2|Bacteria,1MUMY@1224|Proteobacteria,42N1B@68525|delta/epsilon subdivisions,2WJWS@28221|Deltaproteobacteria,2MGEG@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	PFAM FAD dependent oxidoreductase	glpD	-	1.1.5.3	ko:K00111	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	DAO,DAO_C
k141_1628_3	1265505.ATUG01000002_gene1278	9.03e-151	436.0	COG0182@1|root,COG0182@2|Bacteria,1MUPM@1224|Proteobacteria,42MJ2@68525|delta/epsilon subdivisions,2WJQB@28221|Deltaproteobacteria,2MITS@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)	mtnA	-	5.3.1.23	ko:K08963	ko00270,ko01100,map00270,map01100	M00034	R04420	RC01151	ko00000,ko00001,ko00002,ko01000	-	-	-	IF-2B
k141_1628_4	1268635.Loa_00695	4e-132	407.0	COG3243@1|root,COG3243@2|Bacteria,1MU68@1224|Proteobacteria,1RPVQ@1236|Gammaproteobacteria,1JDNP@118969|Legionellales	118969|Legionellales	I	Poly-beta-hydroxybutyrate polymerase N terminal	phbC_2	-	-	ko:K03821	ko00650,map00650	-	R04254	RC00004	ko00000,ko00001,ko01000	-	-	-	PHBC_N,PhaC_N
k141_1628_5	1161902.HMPREF0378_1658	4.23e-36	137.0	COG3315@1|root,COG3315@2|Bacteria,1UPJI@1239|Firmicutes,24BUU@186801|Clostridia	186801|Clostridia	Q	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	LCM
k141_1628_6	96561.Dole_2996	2.58e-32	117.0	COG1522@1|root,COG1522@2|Bacteria,1RCY6@1224|Proteobacteria,42R2R@68525|delta/epsilon subdivisions,2WMSJ@28221|Deltaproteobacteria,2MJRA@213118|Desulfobacterales	28221|Deltaproteobacteria	K	transcriptional regulator, AsnC family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_24,HTH_AsnC-type
k141_1354_1	94122.Shewana3_4244	4.72e-169	503.0	COG0610@1|root,COG0610@2|Bacteria,1MU96@1224|Proteobacteria,1RP2Q@1236|Gammaproteobacteria,2QA0Z@267890|Shewanellaceae	1236|Gammaproteobacteria	V	Subunit R is required for both nuclease and ATPase activities, but not for modification	hsdR	-	3.1.21.3	ko:K01153	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	DUF3387,HSDR_N,ResIII
k141_2643_2	1348635.BBJY01000016_gene4046	1.02e-173	490.0	COG1560@1|root,COG1560@2|Bacteria,1MVNI@1224|Proteobacteria,1RMZ5@1236|Gammaproteobacteria,1XSK3@135623|Vibrionales	135623|Vibrionales	M	Catalyzes the transfer of laurate from lauroyl-acyl carrier protein (ACP) to Kdo(2)-lipid IV(A) to form Kdo(2)- (lauroyl)-lipid IV(A)	lpxL	-	2.3.1.241	ko:K02517	ko00540,ko01100,map00540,map01100	M00060	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Lip_A_acyltrans
k141_2964_1	298386.PBPRB1904	0.0	882.0	COG0370@1|root,COG0370@2|Bacteria,1MUZC@1224|Proteobacteria,1RME9@1236|Gammaproteobacteria,1Y0KH@135623|Vibrionales	135623|Vibrionales	P	Conserved hypothetical ATP binding protein	-	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoB_C,FeoB_N,Gate
k141_5311_1	318464.IO99_08095	2.47e-83	265.0	COG1070@1|root,COG1070@2|Bacteria,1TQ1I@1239|Firmicutes,247NR@186801|Clostridia,36F3K@31979|Clostridiaceae	186801|Clostridia	G	Carbohydrate kinase, FGGY	-	-	2.7.1.17	ko:K00854	ko00040,ko01100,map00040,map01100	M00014	R01639	RC00002,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	-	FGGY_C,FGGY_N
k141_5311_2	1304885.AUEY01000010_gene1666	1.1e-134	406.0	COG0578@1|root,COG0578@2|Bacteria,1MUMY@1224|Proteobacteria,42N1B@68525|delta/epsilon subdivisions,2WJ25@28221|Deltaproteobacteria,2MPYQ@213118|Desulfobacterales	28221|Deltaproteobacteria	C	C-terminal domain of alpha-glycerophosphate oxidase	-	-	1.1.5.3	ko:K00111	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	DAO,DAO_C
k141_5311_3	484770.UFO1_3106	7.76e-07	56.2	COG2186@1|root,COG2186@2|Bacteria,1V2TU@1239|Firmicutes,4H32F@909932|Negativicutes	909932|Negativicutes	K	PFAM GntR domain protein, regulatory protein GntR HTH	-	-	-	ko:K05799	-	-	-	-	ko00000,ko03000	-	-	-	FCD,GntR
k141_5312_1	1085623.GNIT_2555	2.77e-32	127.0	COG1835@1|root,COG1835@2|Bacteria,1N0EY@1224|Proteobacteria,1SFFV@1236|Gammaproteobacteria,46913@72275|Alteromonadaceae	1236|Gammaproteobacteria	I	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
k141_5313_1	568768.CM001975_gene2014	4.91e-18	80.5	COG1182@1|root,COG1182@2|Bacteria,1P59R@1224|Proteobacteria,1S337@1236|Gammaproteobacteria,2JBQW@204037|Dickeya	1236|Gammaproteobacteria	C	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity	azoR	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0010181,GO:0016491,GO:0016651,GO:0016655,GO:0016661,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0046857,GO:0048037,GO:0050446,GO:0050662,GO:0050896,GO:0055114,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	ko:K01118	-	-	-	-	ko00000,ko01000	-	-	-	Flavodoxin_2
k141_5313_2	1348635.BBJY01000005_gene3275	1.61e-28	107.0	2B24R@1|root,31UMW@2|Bacteria,1QSHI@1224|Proteobacteria,1THZZ@1236|Gammaproteobacteria,1XY1S@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_2648_1	1517681.HW45_18095	1.73e-14	72.8	COG1115@1|root,COG1115@2|Bacteria,1MUI3@1224|Proteobacteria,1RMNF@1236|Gammaproteobacteria,1XUBZ@135623|Vibrionales	135623|Vibrionales	U	COG1115 Na alanine symporter	-	-	-	ko:K03310	-	-	-	-	ko00000	2.A.25	-	-	Na_Ala_symp
k141_2648_2	595494.Tola_2293	6.74e-153	438.0	COG1454@1|root,COG1454@2|Bacteria,1MVPH@1224|Proteobacteria,1RMVU@1236|Gammaproteobacteria,1Y6CX@135624|Aeromonadales	135624|Aeromonadales	C	Iron-containing alcohol dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Fe-ADH
k141_4361_1	1121289.JHVL01000012_gene1726	9.15e-45	157.0	COG0427@1|root,COG0427@2|Bacteria,1TPHC@1239|Firmicutes,247V0@186801|Clostridia,36FHR@31979|Clostridiaceae	186801|Clostridia	C	acetyl-CoA hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	AcetylCoA_hyd_C,AcetylCoA_hydro
k141_4361_2	370438.PTH_2046	1.21e-17	92.8	COG2271@1|root,COG2271@2|Bacteria,1V0WU@1239|Firmicutes,25E6S@186801|Clostridia	186801|Clostridia	G	PFAM Major Facilitator Superfamily	-	-	-	ko:K08177	-	-	-	-	ko00000,ko02000	2.A.1.11	-	-	MFS_1
k141_4361_3	1304284.L21TH_1621	6.09e-132	397.0	COG3829@1|root,COG3829@2|Bacteria,1TP0E@1239|Firmicutes,247MB@186801|Clostridia,36DY7@31979|Clostridiaceae	186801|Clostridia	KT	PFAM sigma-54 factor interaction domain-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,PAS,PAS_4,PAS_9,Sigma54_activat
k141_2649_1	1121396.KB892957_gene3250	3.4e-54	177.0	2C957@1|root,337JX@2|Bacteria,1N8TQ@1224|Proteobacteria,42WMB@68525|delta/epsilon subdivisions,2WSI6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	FeoA family	-	-	-	-	-	-	-	-	-	-	-	-	FeoA
k141_2965_1	367737.Abu_0678	2.47e-95	297.0	COG0367@1|root,COG0367@2|Bacteria,1MW4E@1224|Proteobacteria,42MEI@68525|delta/epsilon subdivisions,2YND5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	asparagine	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
k141_2965_2	316058.RPB_1547	1.02e-49	179.0	COG0438@1|root,COG0438@2|Bacteria,1R7HK@1224|Proteobacteria,2U0X1@28211|Alphaproteobacteria,3JXPY@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
k141_2965_3	1408452.JAGZ01000001_gene3471	6.89e-09	65.5	COG0438@1|root,COG0438@2|Bacteria,2GM6D@201174|Actinobacteria,2336Q@1762|Mycobacteriaceae	201174|Actinobacteria	M	GDP-mannose-dependent alpha-(1-6)-phosphatidylinositol monomannoside mannosyltransferase	pimB	GO:0000009,GO:0000030,GO:0003674,GO:0003824,GO:0004376,GO:0005575,GO:0005623,GO:0005886,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016758,GO:0033164,GO:0040007,GO:0043750,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0046467,GO:0070085,GO:0071704,GO:0071944,GO:0097502,GO:1901135,GO:1901137,GO:1901576,GO:1903509	2.4.1.346	ko:K13668	-	-	R11703,R11704	-	ko00000,ko01000,ko01003	-	GT4	-	Glyco_transf_4,Glycos_transf_1
k141_1355_1	1304885.AUEY01000090_gene2887	1.43e-13	71.2	COG0303@1|root,COG2191@1|root,COG0303@2|Bacteria,COG2191@2|Bacteria,1MYKY@1224|Proteobacteria,42NIJ@68525|delta/epsilon subdivisions,2WJ0M@28221|Deltaproteobacteria,2MPIP@213118|Desulfobacterales	28221|Deltaproteobacteria	CH	FmdE, Molybdenum formylmethanofuran dehydrogenase operon	-	-	1.2.7.12	ko:K11261	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00567	R03015,R08060,R11743	RC00197,RC00323	ko00000,ko00001,ko00002,ko01000	-	-	-	FmdE,MoCF_biosynth
k141_1355_3	96561.Dole_3268	6.36e-86	299.0	COG0784@1|root,COG2202@1|root,COG3275@1|root,COG4191@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG3275@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42M1R@68525|delta/epsilon subdivisions,2WK3J@28221|Deltaproteobacteria,2MI5F@213118|Desulfobacterales	28221|Deltaproteobacteria	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg,SBP_bac_3
k141_5315_2	1304885.AUEY01000015_gene2991	4.77e-39	136.0	2E1XZ@1|root,32X6W@2|Bacteria,1N6BA@1224|Proteobacteria,42UBW@68525|delta/epsilon subdivisions,2WR12@28221|Deltaproteobacteria,2MKEJ@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_2966_1	316275.VSAL_I1306	7.17e-88	273.0	COG1167@1|root,COG1167@2|Bacteria,1MUJE@1224|Proteobacteria,1RXYA@1236|Gammaproteobacteria,1XVSK@135623|Vibrionales	135623|Vibrionales	K	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2,GntR
k141_2967_1	439235.Dalk_0514	8.44e-90	274.0	COG2070@1|root,COG2070@2|Bacteria,1MWPC@1224|Proteobacteria,43AEV@68525|delta/epsilon subdivisions,2WKWE@28221|Deltaproteobacteria,2MJ82@213118|Desulfobacterales	68525|delta/epsilon subdivisions	S	PFAM 2-nitropropane dioxygenase NPD	-	-	1.3.1.9	ko:K02371	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00083	R04429,R04724,R04955,R04958,R04961,R04966,R04969,R07765	RC00052,RC00076	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	NMO
k141_1356_1	675815.VOA_002353	4.22e-85	264.0	COG1940@1|root,COG1940@2|Bacteria,1MX6M@1224|Proteobacteria,1RNZ1@1236|Gammaproteobacteria,1XTAB@135623|Vibrionales	135623|Vibrionales	GK	COG1940 Transcriptional regulator sugar kinase	mlc	-	-	ko:K15545	-	-	-	-	ko00000,ko03000	-	-	-	ROK
k141_1356_2	675815.VOA_002352	2.49e-115	338.0	COG0784@1|root,COG0835@1|root,COG0784@2|Bacteria,COG0835@2|Bacteria,1N81M@1224|Proteobacteria,1RPS1@1236|Gammaproteobacteria,1XT9E@135623|Vibrionales	135623|Vibrionales	T	COG0835 Chemotaxis signal transduction protein	-	-	-	ko:K03415	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	CheW,Response_reg
k141_1630_1	1111728.ATYS01000003_gene1782	2.85e-13	70.5	COG0730@1|root,COG0730@2|Bacteria,1MXNM@1224|Proteobacteria,1RRH4@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	membrane transporter protein	yfcA	GO:0005575,GO:0005623,GO:0005886,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0016020,GO:0044464,GO:0050896,GO:0071944	-	ko:K07090,ko:K11312	-	-	-	-	ko00000	-	-	-	TauE
k141_1630_2	1515746.HR45_09595	2.97e-95	289.0	COG0834@1|root,COG0834@2|Bacteria,1RD01@1224|Proteobacteria,1S43D@1236|Gammaproteobacteria,2QBE2@267890|Shewanellaceae	1236|Gammaproteobacteria	ET	ABC-type amino acid transport signal transduction systems periplasmic component domain	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_3
k141_1630_3	1219077.VAZ01S_026_00680	3.56e-39	139.0	COG1846@1|root,COG1846@2|Bacteria,1QVN5@1224|Proteobacteria,1T2FF@1236|Gammaproteobacteria,1Y37I@135623|Vibrionales	135623|Vibrionales	K	Acetyltransferase (GNAT) domain	-	-	-	ko:K03828	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_1,MarR_2
k141_1630_4	1348635.BBJY01000005_gene3327	6.2e-235	654.0	COG1133@1|root,COG1133@2|Bacteria,1QU39@1224|Proteobacteria,1T1PR@1236|Gammaproteobacteria,1XV6E@135623|Vibrionales	135623|Vibrionales	I	SbmA/BacA-like family	-	-	-	ko:K17938	-	-	-	-	ko00000,ko02000	9.A.18.1	-	-	SbmA_BacA
k141_1630_6	998088.B565_1702	2.78e-61	221.0	COG0840@1|root,COG4564@1|root,COG0840@2|Bacteria,COG4564@2|Bacteria,1MU9B@1224|Proteobacteria,1RMV2@1236|Gammaproteobacteria,1Y3WT@135624|Aeromonadales	135624|Aeromonadales	NT	Cache_2	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal,sCache_2
k141_1630_7	449447.MAE_12400	4.66e-55	197.0	COG1404@1|root,COG2931@1|root,COG1404@2|Bacteria,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	bhp	-	-	ko:K13735,ko:K20276,ko:K21449	ko02024,ko05100,map02024,map05100	-	-	-	ko00000,ko00001,ko02000	1.B.40.2	-	-	B_lectin,Big_3_2,Big_5,Calx-beta,DUF4347,HemolysinCabind
k141_2968_1	575788.VS_1869	4.72e-193	542.0	COG3547@1|root,COG3547@2|Bacteria,1QJED@1224|Proteobacteria,1THDR@1236|Gammaproteobacteria,1XUEV@135623|Vibrionales	135623|Vibrionales	L	Evidence 2b Function of strongly homologous gene	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k141_2968_2	391595.RLO149_c018720	3.48e-52	182.0	COG0210@1|root,COG0210@2|Bacteria,1MXV9@1224|Proteobacteria,2TUBV@28211|Alphaproteobacteria,2P4UV@2433|Roseobacter	28211|Alphaproteobacteria	L	UvrD/REP helicase N-terminal domain	-	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AAA_19,UvrD-helicase,UvrD_C
k141_5318_1	96561.Dole_0959	5.07e-204	578.0	COG0527@1|root,COG0527@2|Bacteria,1MVSI@1224|Proteobacteria,42NCA@68525|delta/epsilon subdivisions,2WIVC@28221|Deltaproteobacteria,2MMWX@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Amino acid kinase family	-	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT_7
k141_1358_1	515618.RIEPE_0332	1.23e-26	115.0	COG0477@1|root,COG2814@2|Bacteria,1MVZI@1224|Proteobacteria,1RPBT@1236|Gammaproteobacteria	1236|Gammaproteobacteria	EGP	Major facilitator superfamily	hcaT	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	1.5.1.2	ko:K00286,ko:K05820	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	M00015	R01248,R01251,R03291,R03293	RC00054,RC00083	ko00000,ko00001,ko00002,ko01000,ko02000	2.A.1.27	-	iECIAI39_1322.ECIAI39_2737,iEcSMS35_1347.EcSMS35_2688,iSFV_1184.SFV_2584,iSF_1195.SF2583,iS_1188.S2755	MFS_1_like
k141_1358_3	1278309.KB907103_gene1114	1.92e-08	54.3	2DPGF@1|root,331YU@2|Bacteria,1N6ZX@1224|Proteobacteria,1SDQJ@1236|Gammaproteobacteria,1XMBB@135619|Oceanospirillales	135619|Oceanospirillales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_1358_4	172088.AUGA01000006_gene8049	4.5e-08	55.5	COG4670@1|root,COG4670@2|Bacteria,1MUJW@1224|Proteobacteria,2TRRK@28211|Alphaproteobacteria,3JWB5@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	I	Coenzyme A transferase	pct	-	2.8.3.1	ko:K01026	ko00620,ko00640,ko00643,ko01100,ko01120,map00620,map00640,map00643,map01100,map01120	-	R00928,R01449,R05508	RC00012,RC00014,RC00137	ko00000,ko00001,ko01000	-	-	-	CoA_trans
k141_1631_1	1307759.JOMJ01000003_gene1687	6.65e-33	128.0	COG0840@1|root,COG2703@1|root,COG0840@2|Bacteria,COG2703@2|Bacteria,1RBB1@1224|Proteobacteria,42RNA@68525|delta/epsilon subdivisions,2WNGN@28221|Deltaproteobacteria,2MGVG@213115|Desulfovibrionales	28221|Deltaproteobacteria	NPT	PFAM chemotaxis	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	Hemerythrin,MCPsignal,PilJ
k141_2100_14	697303.Thewi_0156	1.49e-107	325.0	COG0009@1|root,COG0009@2|Bacteria,1TP1I@1239|Firmicutes,248HS@186801|Clostridia,42ENS@68295|Thermoanaerobacterales	186801|Clostridia	H	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine	sua	-	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	SUA5,Sua5_yciO_yrdC
k141_2100_15	656519.Halsa_0392	1.66e-28	110.0	COG0394@1|root,COG0394@2|Bacteria,1VA05@1239|Firmicutes,25CRM@186801|Clostridia	186801|Clostridia	T	Low molecular weight phosphotyrosine protein phosphatase	ywlE	-	3.1.3.48,3.9.1.2	ko:K01104,ko:K20201	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
k141_2100_16	1511.CLOST_2129	2.64e-67	207.0	COG0698@1|root,COG0698@2|Bacteria,1V3HE@1239|Firmicutes,24JWT@186801|Clostridia,25RC3@186804|Peptostreptococcaceae	186801|Clostridia	G	isomerase B	rpiB	-	5.3.1.6	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01056,R09030	RC00376,RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	LacAB_rpiB
k141_2100_17	1511.CLOST_2128	1.01e-116	337.0	COG0035@1|root,COG0035@2|Bacteria,1TPMT@1239|Firmicutes,248FV@186801|Clostridia,25QEK@186804|Peptostreptococcaceae	186801|Clostridia	F	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate	upp	-	2.4.2.9	ko:K00761	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000	-	-	-	UPRTase
k141_2100_18	565033.GACE_0121	1.07e-67	209.0	COG2131@1|root,arCOG01487@2157|Archaea,2XXBC@28890|Euryarchaeota,2464C@183980|Archaeoglobi	183980|Archaeoglobi	F	PFAM CMP dCMP deaminase zinc-binding	-	-	3.5.4.12	ko:K01493	ko00240,ko01100,map00240,map01100	M00429	R01663	RC00074	ko00000,ko00001,ko00002,ko01000,ko02044	-	-	-	dCMP_cyt_deam_1
k141_2100_19	1121324.CLIT_13c01290	1.87e-120	358.0	COG0472@1|root,COG0472@2|Bacteria,1TP9V@1239|Firmicutes,247M7@186801|Clostridia,25R2V@186804|Peptostreptococcaceae	186801|Clostridia	M	Glycosyl transferase family 4	tagO	-	2.7.8.33,2.7.8.35	ko:K02851	-	-	R08856	RC00002	ko00000,ko01000,ko01003,ko01005	-	-	-	Glycos_transf_4
k141_2100_20	1121324.CLIT_13c01300	3.08e-181	514.0	COG0381@1|root,COG0381@2|Bacteria,1TQZT@1239|Firmicutes,247N7@186801|Clostridia	186801|Clostridia	M	Belongs to the UDP-N-acetylglucosamine 2-epimerase family	-	-	5.1.3.14	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	M00362	R00420	RC00290	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase_2
k141_2100_21	293826.Amet_0344	1.31e-13	66.6	2DR0U@1|root,339Q9@2|Bacteria,1VK88@1239|Firmicutes,25Q6W@186801|Clostridia,36P1R@31979|Clostridiaceae	186801|Clostridia	S	Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter	-	-	-	-	-	-	-	-	-	-	-	-	ATPase_gene1
k141_2100_22	293826.Amet_0345	4.81e-22	92.4	2E5CI@1|root,3304M@2|Bacteria,1VGE2@1239|Firmicutes,24RE0@186801|Clostridia,36MX6@31979|Clostridiaceae	186801|Clostridia	S	ATP synthase I chain	atpI2	-	-	-	-	-	-	-	-	-	-	-	ATP-synt_I
k141_2100_23	1121324.CLIT_13c01330	1.52e-79	244.0	COG0356@1|root,COG0356@2|Bacteria,1TQIT@1239|Firmicutes,24A6Q@186801|Clostridia,25R3A@186804|Peptostreptococcaceae	186801|Clostridia	C	it plays a direct role in the translocation of protons across the membrane	atpB	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
k141_2100_24	293826.Amet_0347	4.33e-85	255.0	COG0636@1|root,COG0636@2|Bacteria,1V1B0@1239|Firmicutes,24G2R@186801|Clostridia	186801|Clostridia	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	-	-	-	-	-	-	-	-	-	-	-	-	ATP-synt_C
k141_2100_25	293826.Amet_0348	3.31e-46	149.0	COG0636@1|root,COG0636@2|Bacteria,1V8SD@1239|Firmicutes,24QMQ@186801|Clostridia,36MIS@31979|Clostridiaceae	186801|Clostridia	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpE	-	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
k141_2100_26	1408422.JHYF01000012_gene3251	7.7e-17	80.9	COG0711@1|root,COG0711@2|Bacteria,1VB85@1239|Firmicutes,24RWR@186801|Clostridia,36M51@31979|Clostridiaceae	186801|Clostridia	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	atpF	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	iHN637.CLJU_RS01170	ATP-synt_B
k141_2100_27	1265310.CCBD010000044_gene632	0.000824	47.4	COG0711@1|root,COG0712@1|root,COG0711@2|Bacteria,COG0712@2|Bacteria,2GMJ5@201174|Actinobacteria,232X8@1762|Mycobacteriaceae	201174|Actinobacteria	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpH	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	-	ko:K02109,ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B,OSCP
k141_2100_28	1511.CLOST_2118	3.5e-285	788.0	COG0056@1|root,COG0056@2|Bacteria,1TNZ8@1239|Firmicutes,248IY@186801|Clostridia,25QJR@186804|Peptostreptococcaceae	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
k141_2100_29	1286171.EAL2_c03910	6.36e-114	336.0	COG0224@1|root,COG0224@2|Bacteria,1TPBX@1239|Firmicutes,2486Q@186801|Clostridia,25VH1@186806|Eubacteriaceae	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	-	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
k141_2100_30	1286171.EAL2_c03920	2.72e-288	793.0	COG0055@1|root,COG0055@2|Bacteria,1TPGF@1239|Firmicutes,2489W@186801|Clostridia,25UUG@186806|Eubacteriaceae	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
k141_2100_31	1511.CLOST_2115	1.99e-38	133.0	COG0355@1|root,COG0355@2|Bacteria,1VA89@1239|Firmicutes,24ND7@186801|Clostridia,25RTG@186804|Peptostreptococcaceae	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpC	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	iHN637.CLJU_RS01195	ATP-synt_DE,ATP-synt_DE_N
k141_2100_32	1121324.CLIT_13c01410	1.96e-37	137.0	2ECTX@1|root,336RF@2|Bacteria,1VGMY@1239|Firmicutes,24SIP@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_2100_33	1476973.JMMB01000007_gene3205	1.64e-40	138.0	COG0736@1|root,COG0736@2|Bacteria,1VA0T@1239|Firmicutes,24RC0@186801|Clostridia,25RK6@186804|Peptostreptococcaceae	186801|Clostridia	I	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein	acpS	-	2.7.8.7	ko:K00997	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS01470	ACPS
k141_2100_34	1511.CLOST_2112	2.04e-139	409.0	COG0787@1|root,COG0787@2|Bacteria,1TNYY@1239|Firmicutes,2480T@186801|Clostridia,25R0S@186804|Peptostreptococcaceae	186801|Clostridia	M	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	alr	-	5.1.1.1	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N
k141_2100_35	1408422.JHYF01000003_gene842	1.03e-07	52.0	COG0864@1|root,COG0864@2|Bacteria,1VA28@1239|Firmicutes,24QKP@186801|Clostridia	186801|Clostridia	K	Transcriptional regulator, CopG family	-	-	-	ko:K07723	-	-	-	-	ko00000,ko02048,ko03000	-	-	-	RHH_1
k141_2100_36	386415.NT01CX_1266	8.19e-57	179.0	COG2337@1|root,COG2337@2|Bacteria,1V6DK@1239|Firmicutes,24JE1@186801|Clostridia,36IPB@31979|Clostridiaceae	186801|Clostridia	L	Toxic component of a toxin-antitoxin (TA) module	ndoA	-	-	ko:K07171	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PemK_toxin
k141_2100_37	457570.Nther_2387	1.08e-19	88.6	2E366@1|root,32Y5Z@2|Bacteria,1VFY1@1239|Firmicutes,24RE8@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_2100_38	1121324.CLIT_13c01490	4.25e-160	484.0	2DBE5@1|root,2Z8QQ@2|Bacteria,1TPFD@1239|Firmicutes,24E93@186801|Clostridia,25QN4@186804|Peptostreptococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 10.00	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_2100_39	1121324.CLIT_13c01500	4.5e-126	374.0	COG2327@1|root,COG2327@2|Bacteria,1TPTI@1239|Firmicutes,248QN@186801|Clostridia,25T1B@186804|Peptostreptococcaceae	186801|Clostridia	S	Polysaccharide pyruvyl transferase	csaB	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1,PS_pyruv_trans
k141_2100_40	1286171.EAL2_c04040	2.03e-91	276.0	COG1922@1|root,COG1922@2|Bacteria,1V3QV@1239|Firmicutes,24AQ3@186801|Clostridia,25XW7@186806|Eubacteriaceae	186801|Clostridia	M	Glycosyl transferase WecB/TagA/CpsF family	tagA	-	2.4.1.187	ko:K05946	ko05111,map05111	-	-	-	ko00000,ko00001,ko01000,ko01003	-	GT26	-	Glyco_tran_WecB,PS_pyruv_trans
k141_2100_41	293826.Amet_4138	3.18e-109	325.0	COG1284@1|root,COG1284@2|Bacteria,1TR9J@1239|Firmicutes,24BGW@186801|Clostridia,36DT5@31979|Clostridiaceae	186801|Clostridia	S	Uncharacterised 5xTM membrane BCR, YitT family COG1284	-	-	-	-	-	-	-	-	-	-	-	-	DUF2179,YitT_membrane
k141_2100_42	1391646.AVSU01000012_gene1807	1.45e-143	412.0	COG3959@1|root,COG3959@2|Bacteria,1TT51@1239|Firmicutes,247IK@186801|Clostridia,25QJW@186804|Peptostreptococcaceae	186801|Clostridia	G	Transketolase	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
k141_2100_43	1408823.AXUS01000010_gene1879	3.38e-154	441.0	COG3958@1|root,COG3958@2|Bacteria,1V0K5@1239|Firmicutes,24914@186801|Clostridia,25QQ5@186804|Peptostreptococcaceae	186801|Clostridia	G	Transketolase	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
k141_2100_44	1347392.CCEZ01000010_gene2408	6.06e-228	649.0	COG1001@1|root,COG1001@2|Bacteria,1TP84@1239|Firmicutes,247KN@186801|Clostridia,36DDA@31979|Clostridiaceae	186801|Clostridia	F	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family	ade	-	3.5.4.2	ko:K01486	ko00230,ko01100,map00230,map01100	-	R01244	RC00477	ko00000,ko00001,ko01000	-	-	-	Adenine_deam_C,Amidohydro_1
k141_2100_45	796945.HMPREF1145_0343	3.26e-38	136.0	COG3331@1|root,COG3331@2|Bacteria,1V3S4@1239|Firmicutes,24G7S@186801|Clostridia,2PS13@265975|Oribacterium	186801|Clostridia	L	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation	recU	-	-	ko:K03700	-	-	-	-	ko00000,ko03400	-	-	-	RecU
k141_2100_46	1121324.CLIT_14c00090	1.23e-148	426.0	COG0784@1|root,COG0835@1|root,COG0784@2|Bacteria,COG0835@2|Bacteria,1TRJU@1239|Firmicutes,24AQW@186801|Clostridia	186801|Clostridia	T	response regulator receiver	cheV	-	2.7.13.3	ko:K03407,ko:K03415	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,Response_reg
k141_2100_47	203119.Cthe_2356	5.19e-117	346.0	COG0379@1|root,COG0379@2|Bacteria,1TP6R@1239|Firmicutes,247IJ@186801|Clostridia,3WGEP@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate	nadA	-	2.5.1.72	ko:K03517	ko00760,ko01100,map00760,map01100	M00115	R04292	RC01119	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS12020	NadA
k141_2100_48	926561.KB900622_gene511	4.85e-160	473.0	COG0029@1|root,COG0029@2|Bacteria,1UHSP@1239|Firmicutes,25E6F@186801|Clostridia,3WAHG@53433|Halanaerobiales	186801|Clostridia	H	Catalyzes the oxidation of L-aspartate to iminoaspartate	nadB	-	1.4.3.16	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	M00115	R00357,R00481	RC00006,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
k141_2100_49	203119.Cthe_2354	6.7e-89	272.0	COG0157@1|root,COG0157@2|Bacteria,1TPQC@1239|Firmicutes,248P2@186801|Clostridia,3WGJ1@541000|Ruminococcaceae	186801|Clostridia	H	Belongs to the NadC ModD family	nadC	-	2.4.2.19	ko:K00767	ko00760,ko01100,map00760,map01100	M00115	R03348	RC02877	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS12010	QRPTase_C,QRPTase_N
k141_2100_50	1033810.HLPCO_002179	2.06e-181	521.0	COG0733@1|root,COG0733@2|Bacteria,2NNP4@2323|unclassified Bacteria	2|Bacteria	S	Sodium:neurotransmitter symporter family	-	-	-	ko:K03308	-	-	-	-	ko00000	2.A.22.4,2.A.22.5	-	-	SNF
k141_2100_51	1408422.JHYF01000003_gene920	1.87e-32	122.0	2C9A0@1|root,32RNW@2|Bacteria,1VCW8@1239|Firmicutes,24HH9@186801|Clostridia,36IW5@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_5,Rep_3
k141_2100_52	37659.JNLN01000001_gene1339	3.94e-39	156.0	COG5001@1|root,COG5001@2|Bacteria,1TP8V@1239|Firmicutes,247PX@186801|Clostridia,36E1W@31979|Clostridiaceae	186801|Clostridia	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	ABC_sub_bind,CHASE,EAL,GGDEF,PAS_3
k141_2100_53	588581.Cpap_2172	1.03e-64	219.0	COG0727@1|root,COG0727@2|Bacteria,1TSB6@1239|Firmicutes,24AQ9@186801|Clostridia,3WIXE@541000|Ruminococcaceae	186801|Clostridia	S	N-methylation of lysine residues in flagellin K00599	fliB	-	-	ko:K18475	-	-	-	-	ko00000,ko01000,ko02035	-	-	-	CxxCxxCC
k141_2100_54	1033737.CAEV01000025_gene379	1.5e-51	183.0	COG2508@1|root,COG2508@2|Bacteria,1V4GV@1239|Firmicutes,24HFE@186801|Clostridia,36VUQ@31979|Clostridiaceae	186801|Clostridia	QT	Purine catabolism regulatory protein-like family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_30,PucR
k141_2100_55	411462.DORLON_01199	5.48e-36	138.0	COG0697@1|root,COG0697@2|Bacteria,1V2EI@1239|Firmicutes,24GU6@186801|Clostridia,27WQE@189330|Dorea	186801|Clostridia	EG	COG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily	-	-	-	-	-	-	-	-	-	-	-	-	EamA
k141_2100_56	1123288.SOV_3c02280	1.73e-76	250.0	COG0727@1|root,COG0727@2|Bacteria,1TSB6@1239|Firmicutes,4H3DJ@909932|Negativicutes	909932|Negativicutes	S	Psort location Cytoplasmic, score	-	-	-	ko:K18475	-	-	-	-	ko00000,ko01000,ko02035	-	-	-	-
k141_2100_57	929506.CbC4_0444	2.04e-183	564.0	COG3291@1|root,COG3291@2|Bacteria,1TSRU@1239|Firmicutes,24BRF@186801|Clostridia,36HRJ@31979|Clostridiaceae	186801|Clostridia	S	hmm pf04151	colG	-	3.4.24.3	ko:K01387	-	-	-	-	ko00000,ko01000,ko01002,ko02042	-	-	-	PKD,PPC,Peptidase_M9,Peptidase_M9_N
k141_2100_58	195103.CPF_0166	1.45e-187	580.0	COG3291@1|root,COG3291@2|Bacteria,1TSRU@1239|Firmicutes,24BRF@186801|Clostridia,36HRJ@31979|Clostridiaceae	186801|Clostridia	S	hmm pf04151	colG	-	3.4.24.3	ko:K01387	-	-	-	-	ko00000,ko01000,ko01002,ko02042	-	-	-	PKD,PPC,Peptidase_M9,Peptidase_M9_N
k141_2100_60	1121324.CLIT_2c02870	1.08e-213	599.0	COG0162@1|root,COG0162@2|Bacteria,1TPGN@1239|Firmicutes,247QC@186801|Clostridia,25R1Z@186804|Peptostreptococcaceae	186801|Clostridia	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	-	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
k141_2100_61	1117318.PRUB_08387	5.55e-71	250.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,2Q1JG@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	T	signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,HAMP,PAS_9,dCache_1
k141_2100_62	1175629.AJTG01000031_gene1547	1.14e-06	52.8	COG3238@1|root,COG3238@2|Bacteria,1V0FB@1239|Firmicutes,4HFG7@91061|Bacilli	91061|Bacilli	S	Putative inner membrane exporter, YdcZ	-	-	-	ko:K09936	ko02024,map02024	-	-	-	ko00000,ko00001,ko02000	2.A.7.21	-	-	DMT_YdcZ
k141_2100_63	290402.Cbei_1744	4.27e-24	98.2	COG3238@1|root,COG3238@2|Bacteria,1V7PX@1239|Firmicutes,24MM7@186801|Clostridia,36KFC@31979|Clostridiaceae	186801|Clostridia	S	Putative inner membrane exporter, YdcZ	-	-	-	ko:K09936	ko02024,map02024	-	-	-	ko00000,ko00001,ko02000	2.A.7.21	-	-	DMT_YdcZ
k141_2100_64	697303.Thewi_1506	4.66e-20	102.0	COG0103@1|root,COG5279@1|root,COG0103@2|Bacteria,COG5279@2|Bacteria,1V8TE@1239|Firmicutes,24CI3@186801|Clostridia,42GHD@68295|Thermoanaerobacterales	186801|Clostridia	D	transglutaminase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,CW_binding_2,Cu_amine_oxidN1,Transglut_core
k141_2100_65	742723.HMPREF9477_00971	8.92e-86	269.0	COG2423@1|root,COG2423@2|Bacteria,1TPHM@1239|Firmicutes,24DP8@186801|Clostridia,27PF2@186928|unclassified Lachnospiraceae	186801|Clostridia	E	Ornithine cyclodeaminase/mu-crystallin family	ocd	-	4.3.1.12	ko:K01750	ko00330,ko01110,ko01130,ko01230,map00330,map01110,map01130,map01230	-	R00671	RC00354	ko00000,ko00001,ko01000	-	-	-	OCD_Mu_crystall
k141_2100_66	1128398.Curi_c26090	2.02e-100	298.0	COG0745@1|root,COG0745@2|Bacteria,1TS81@1239|Firmicutes,248XH@186801|Clostridia,267ZD@186813|unclassified Clostridiales	186801|Clostridia	T	Transcriptional regulatory protein, C terminal	arlR	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
k141_2100_67	635013.TherJR_2683	7.6e-97	308.0	COG0642@1|root,COG2770@1|root,COG2205@2|Bacteria,COG2770@2|Bacteria,1UHQC@1239|Firmicutes,25EVD@186801|Clostridia,267E4@186807|Peptococcaceae	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
k141_2100_68	386456.JQKN01000002_gene2429	4.67e-06	53.5	COG1309@1|root,arCOG02648@2157|Archaea	2157|Archaea	K	COG1309 Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
k141_2100_69	1511.CLOST_1011	3.69e-53	173.0	2C1XY@1|root,32SVI@2|Bacteria,1VCSR@1239|Firmicutes,25CZT@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_2100_70	1511.CLOST_1011	3.54e-52	170.0	2C1XY@1|root,32SVI@2|Bacteria,1VCSR@1239|Firmicutes,25CZT@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_2100_71	1033810.HLPCO_001959	1.1e-178	512.0	COG1055@1|root,COG1055@2|Bacteria,2NPE3@2323|unclassified Bacteria	2|Bacteria	P	Arsenical pump membrane protein	arsA	-	-	ko:K03893	-	-	-	-	ko00000,ko02000	2.A.45.1,3.A.4.1	-	-	CitMHS
k141_2100_73	1391646.AVSU01000099_gene362	3.42e-60	202.0	COG1082@1|root,COG1082@2|Bacteria,1U2VB@1239|Firmicutes,24EE7@186801|Clostridia	186801|Clostridia	G	PFAM Xylose isomerase domain protein TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
k141_2100_74	1157490.EL26_03015	2.34e-20	98.6	28RTZ@1|root,2ZE6B@2|Bacteria,1V1HK@1239|Firmicutes,4IC1K@91061|Bacilli,27AB7@186823|Alicyclobacillaceae	91061|Bacilli	S	Domain of unknown function (DUF4430)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4430
k141_2100_76	1499689.CCNN01000007_gene1133	6.38e-129	394.0	COG0488@1|root,COG0488@2|Bacteria,1UI2R@1239|Firmicutes,25EBF@186801|Clostridia,36UJA@31979|Clostridiaceae	186801|Clostridia	S	ATPases associated with a variety of cellular activities	-	-	-	ko:K16785,ko:K16786,ko:K16787	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ABC_tran
k141_2100_77	1121289.JHVL01000017_gene781	1.54e-74	231.0	COG4720@1|root,COG4720@2|Bacteria,1V2DR@1239|Firmicutes,249XR@186801|Clostridia,36F8J@31979|Clostridiaceae	186801|Clostridia	S	ECF-type riboflavin transporter, S component	-	-	-	ko:K16927	-	M00582	-	-	ko00000,ko00002,ko02000	3.A.1.32	-	-	ECF-ribofla_trS,ECF_trnsprt
k141_2100_78	1121289.JHVL01000017_gene777	6.04e-54	188.0	COG1657@1|root,COG2373@1|root,COG1657@2|Bacteria,COG2373@2|Bacteria,1U1T6@1239|Firmicutes,24EBP@186801|Clostridia	186801|Clostridia	I	S-layer homology domain	-	-	-	-	-	-	-	-	-	-	-	-	SLH
k141_2100_79	748727.CLJU_c08990	3.56e-06	57.0	COG4886@1|root,COG5279@1|root,COG4886@2|Bacteria,COG5279@2|Bacteria,1V8TE@1239|Firmicutes,24CI3@186801|Clostridia,36GZB@31979|Clostridiaceae	186801|Clostridia	D	transglutaminase	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,Cu_amine_oxidN1,Transglut_core
k141_2100_80	1078085.HMPREF1210_01640	5.17e-07	60.8	COG1657@1|root,COG2247@1|root,COG1657@2|Bacteria,COG2247@2|Bacteria,1UZVS@1239|Firmicutes,4HDE7@91061|Bacilli,26GAC@186818|Planococcaceae	91061|Bacilli	I	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,DUF4430,Gram_pos_anchor,Prenyltrans,SLH,SQHop_cyclase_C
k141_2100_82	293826.Amet_3064	6.43e-42	165.0	COG0827@1|root,COG0827@2|Bacteria,1UHWQ@1239|Firmicutes,25E5N@186801|Clostridia,36UQ7@31979|Clostridiaceae	186801|Clostridia	LV	TaqI-like C-terminal specificity domain	-	-	2.1.1.72	ko:K07317	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	Eco57I,HSDR_N,HTH_17,N6_Mtase,TaqI_C
k141_4530_1	715451.ambt_10315	9.69e-145	438.0	COG2203@1|root,COG5001@1|root,COG2203@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,4645Y@72275|Alteromonadaceae	1236|Gammaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	CZB,DUF4118,EAL,GAF_2,GGDEF,PAS_3,PAS_4,PAS_9,Protoglobin
k141_4844_1	392499.Swit_0005	4.26e-37	149.0	COG2268@1|root,COG2268@2|Bacteria,1P50K@1224|Proteobacteria,2TTVY@28211|Alphaproteobacteria,2K0BQ@204457|Sphingomonadales	204457|Sphingomonadales	S	Flotillin	-	-	-	-	-	-	-	-	-	-	-	-	Band_7,Flot
k141_2101_1	716544.wcw_0519	2.42e-102	305.0	COG0667@1|root,COG0667@2|Bacteria,2JGWJ@204428|Chlamydiae	204428|Chlamydiae	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
k141_4845_1	1187848.AJYQ01000066_gene3523	2.71e-49	164.0	COG0745@1|root,COG0745@2|Bacteria,1MY3D@1224|Proteobacteria,1RPKN@1236|Gammaproteobacteria,1XSSJ@135623|Vibrionales	135623|Vibrionales	K	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
k141_4531_1	55601.VANGNB10_cII0570c	1.27e-92	289.0	COG4166@1|root,COG4166@2|Bacteria,1MUVU@1224|Proteobacteria,1RMA1@1236|Gammaproteobacteria,1XUMM@135623|Vibrionales	135623|Vibrionales	E	ABC-type oligopeptide transport system, periplasmic component	-	-	-	ko:K13893	ko02010,map02010	M00349	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.21,3.A.1.5.24	-	-	SBP_bac_5
k141_3525_1	1449065.JMLL01000017_gene3861	3.54e-34	130.0	COG0845@1|root,COG0845@2|Bacteria,1R99C@1224|Proteobacteria,2U9ZZ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
k141_3525_2	1268237.G114_13763	7.43e-117	361.0	COG1538@1|root,COG1538@2|Bacteria,1MUHM@1224|Proteobacteria,1RNNS@1236|Gammaproteobacteria,1Y539@135624|Aeromonadales	135624|Aeromonadales	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
k141_4532_1	1125863.JAFN01000001_gene2021	7.78e-68	224.0	COG4974@1|root,COG4974@2|Bacteria,1NY1A@1224|Proteobacteria,42NX3@68525|delta/epsilon subdivisions,2WME4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	High confidence in function and specificity	-	-	-	ko:K07484	-	-	-	-	ko00000	-	-	-	DDE_Tnp_IS66,DDE_Tnp_IS66_C,LZ_Tnp_IS66,zf-IS66
k141_4847_1	1051646.VITU9109_00560	1.14e-89	280.0	COG0582@1|root,COG0582@2|Bacteria,1N73Z@1224|Proteobacteria,1SEHI@1236|Gammaproteobacteria,1XTD7@135623|Vibrionales	135623|Vibrionales	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
k141_4533_1	177439.DP2705	1.35e-17	85.9	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42MZX@68525|delta/epsilon subdivisions,2WMCT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	NT	chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal,dCache_1
k141_4848_1	526218.Sterm_3135	1.07e-60	193.0	COG1859@1|root,COG1859@2|Bacteria,379E0@32066|Fusobacteria	32066|Fusobacteria	H	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase	kptA	-	-	ko:K07559	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PTS_2-RNA
k141_3819_1	247633.GP2143_07854	5.42e-06	53.9	COG4590@1|root,COG4590@2|Bacteria,1QTTD@1224|Proteobacteria,1T1GK@1236|Gammaproteobacteria,1J599@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	P	transport system permease	pstC	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
k141_3819_2	675814.VIC_002043	0.0	1132.0	COG0855@1|root,COG0855@2|Bacteria,1MUM3@1224|Proteobacteria,1RNRX@1236|Gammaproteobacteria,1XSGM@135623|Vibrionales	135623|Vibrionales	F	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008976,GO:0009358,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0032991,GO:0044237,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
k141_3819_3	243277.VC_0722	2.51e-38	141.0	COG0248@1|root,COG0248@2|Bacteria,1MV35@1224|Proteobacteria,1RN3V@1236|Gammaproteobacteria,1XTUA@135623|Vibrionales	135623|Vibrionales	FP	Belongs to the GppA Ppx family	ppx	GO:0003674,GO:0003824,GO:0004309,GO:0006082,GO:0006793,GO:0006797,GO:0006798,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0071704,GO:1901575	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	Ppx-GppA
k141_3157_5	675813.VIB_001301	1.26e-131	403.0	2DMEK@1|root,32R04@2|Bacteria,1QYX8@1224|Proteobacteria,1T3WD@1236|Gammaproteobacteria,1Y37X@135623|Vibrionales	135623|Vibrionales	S	Protein of unknown function (DUF3466)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3466
k141_3157_6	243277.VC_1486	0.0	976.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,1RPCU@1236|Gammaproteobacteria,1XT00@135623|Vibrionales	135623|Vibrionales	S	COG0488 ATPase components of ABC transporters with duplicated ATPase domains	uup	-	-	ko:K15738	-	-	-	-	ko00000,ko02000	3.A.1.120.6	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn,MMR_HSR1
k141_3157_7	243277.VC_1488	0.0	1052.0	COG0116@1|root,COG1092@1|root,COG0116@2|Bacteria,COG1092@2|Bacteria,1MUQM@1224|Proteobacteria,1RNMH@1236|Gammaproteobacteria,1XSNR@135623|Vibrionales	135623|Vibrionales	J	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA	rlmL	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0008990,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.173,2.1.1.264	ko:K12297	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM,THUMP,UPF0020
k141_3157_9	345073.VC395_1610	4.79e-78	237.0	28I7M@1|root,2Z8AH@2|Bacteria,1N1DT@1224|Proteobacteria,1RYK3@1236|Gammaproteobacteria,1XVKE@135623|Vibrionales	135623|Vibrionales	D	Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ	zapC	-	-	ko:K18657	-	-	-	-	ko00000,ko03036	-	-	-	ZapC
k141_3157_11	1219065.VPR01S_01_00270	0.0	2166.0	COG2902@1|root,COG2902@2|Bacteria,1MXNV@1224|Proteobacteria,1RQVZ@1236|Gammaproteobacteria,1XUBT@135623|Vibrionales	135623|Vibrionales	E	NAD-specific glutamate dehydrogenase	gdhB	-	1.4.1.2	ko:K15371	ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100	-	R00243	RC00006,RC02799	ko00000,ko00001,ko01000	-	-	-	Bac_GDH
k141_3157_12	298386.PBPRB0483	1.41e-144	411.0	COG0500@1|root,COG2226@2|Bacteria,1N9JV@1224|Proteobacteria,1RP9E@1236|Gammaproteobacteria,1XUNG@135623|Vibrionales	135623|Vibrionales	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
k141_3157_13	715451.ambt_20235	4.3e-45	149.0	COG2315@1|root,COG2315@2|Bacteria,1RHEZ@1224|Proteobacteria,1S69J@1236|Gammaproteobacteria,46ASX@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	YjbR	-	-	-	-	-	-	-	-	-	-	-	-	YjbR
k141_3157_14	575788.VS_1610	1.08e-82	247.0	COG4405@1|root,COG4405@2|Bacteria,1N2T4@1224|Proteobacteria,1S2GH@1236|Gammaproteobacteria,1XX11@135623|Vibrionales	135623|Vibrionales	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	ASCH
k141_3157_15	55601.VANGNB10_cI1258	0.0	1299.0	COG0308@1|root,COG0308@2|Bacteria,1MUCI@1224|Proteobacteria,1RMA7@1236|Gammaproteobacteria,1XUSZ@135623|Vibrionales	135623|Vibrionales	E	COG0308 Aminopeptidase N	pepN	-	3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	DUF3458,DUF3458_C,Peptidase_M1
k141_3157_16	1051646.VITU9109_19547	9.74e-72	224.0	2AM7R@1|root,31C2D@2|Bacteria,1QJDQ@1224|Proteobacteria,1THCV@1236|Gammaproteobacteria,1XU2R@135623|Vibrionales	135623|Vibrionales	-	-	VP1605	-	-	-	-	-	-	-	-	-	-	-	-
k141_3157_17	1219065.VPR01S_01_00240	0.0	1006.0	COG0793@1|root,COG0793@2|Bacteria,1MU39@1224|Proteobacteria,1RMSR@1236|Gammaproteobacteria,1XT5Z@135623|Vibrionales	135623|Vibrionales	M	protease	prc	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	BAGE,DUF3340,PDZ,Peptidase_S41
k141_3157_19	1280001.BAOA01000077_gene3093	3.84e-82	246.0	COG1956@1|root,COG1956@2|Bacteria,1RDBM@1224|Proteobacteria,1S6QU@1236|Gammaproteobacteria,1XX5M@135623|Vibrionales	135623|Vibrionales	T	GAF domain-containing protein	yebR	-	1.8.4.14	ko:K08968	ko00270,map00270	-	R02025	RC00639	ko00000,ko00001,ko01000	-	-	-	GAF_2
k141_1937_8	672.VV93_v1c41090	2.31e-200	560.0	COG0516@1|root,COG0516@2|Bacteria,1MUJM@1224|Proteobacteria,1RPZY@1236|Gammaproteobacteria,1XUGZ@135623|Vibrionales	135623|Vibrionales	F	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides	guaC	GO:0003674,GO:0003824,GO:0003920,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0015949,GO:0016491,GO:0016651,GO:0016657,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:1901360	1.7.1.7	ko:K00364	ko00230,map00230	-	R01134	RC00457	ko00000,ko00001,ko01000	-	-	-	IMPDH
k141_3629_1	595494.Tola_1473	2.9e-147	426.0	COG2223@1|root,COG2223@2|Bacteria,1MXAA@1224|Proteobacteria,1RMZZ@1236|Gammaproteobacteria,1Y583@135624|Aeromonadales	135624|Aeromonadales	P	Major Facilitator Superfamily	-	-	-	ko:K08223	-	-	-	-	ko00000,ko02000	2.A.1.35	-	-	MFS_1
k141_3629_2	1238450.VIBNISOn1_90009	1.53e-182	513.0	COG2433@1|root,COG2433@2|Bacteria,1QYJZ@1224|Proteobacteria,1RUCR@1236|Gammaproteobacteria,1XX4Y@135623|Vibrionales	135623|Vibrionales	S	Transposase IS66 family	-	-	-	ko:K07484	-	-	-	-	ko00000	-	-	-	DDE_Tnp_IS66
k141_3629_3	1238450.VIBNISOn1_90010	1.07e-42	140.0	2EP7M@1|root,33GUB@2|Bacteria,1P4B3@1224|Proteobacteria,1SUKP@1236|Gammaproteobacteria,1Y1D3@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_3629_4	1051646.VITU9109_20309	2.01e-29	120.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1R81Y@1224|Proteobacteria,1RYQ2@1236|Gammaproteobacteria,1XUTT@135623|Vibrionales	135623|Vibrionales	T	COG0642 Signal transduction histidine kinase	luxN	-	2.7.13.3	ko:K15850	ko02020,ko02024,map02020,map02024	-	-	-	ko00000,ko00001,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,Response_reg
k141_5219_2	1167006.UWK_00883	2.99e-59	192.0	COG1592@1|root,COG4244@1|root,COG1592@2|Bacteria,COG4244@2|Bacteria,1RGN3@1224|Proteobacteria,42S4Q@68525|delta/epsilon subdivisions,2WNKZ@28221|Deltaproteobacteria,2MJV6@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Rubrerythrin	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_303_1	1307759.JOMJ01000003_gene783	1.58e-123	376.0	COG0556@1|root,COG0556@2|Bacteria,1MUFK@1224|Proteobacteria,42MFA@68525|delta/epsilon subdivisions,2WJ20@28221|Deltaproteobacteria,2M82W@213115|Desulfovibrionales	28221|Deltaproteobacteria	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
k141_303_2	264732.Moth_0256	2.09e-60	206.0	COG0322@1|root,COG0322@2|Bacteria,1TP4B@1239|Firmicutes,247TQ@186801|Clostridia,42ER0@68295|Thermoanaerobacterales	186801|Clostridia	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	-	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N
k141_4261_1	1203605.HMPREF1531_00729	7.02e-89	270.0	COG4816@1|root,COG4816@2|Bacteria	2|Bacteria	E	ethanolamine catabolic process	pduB	-	-	-	-	-	-	-	-	-	-	-	BMC
k141_4653_1	1232437.KL661980_gene3725	1.16e-84	266.0	COG0741@1|root,COG1388@1|root,COG0741@2|Bacteria,COG1388@2|Bacteria,1MWKE@1224|Proteobacteria,42MWF@68525|delta/epsilon subdivisions,2WKAQ@28221|Deltaproteobacteria,2MIMD@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Lysin motif	-	-	-	ko:K08307	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	LysM,SLT
k141_4955_3	1348635.BBJY01000009_gene1520	0.0	1100.0	COG1198@1|root,COG1198@2|Bacteria,1MUUZ@1224|Proteobacteria,1RPZ7@1236|Gammaproteobacteria,1XT0R@135623|Vibrionales	135623|Vibrionales	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C
k141_4955_4	243277.VC_2677	1.16e-194	545.0	COG1609@1|root,COG1609@2|Bacteria,1MVUR@1224|Proteobacteria,1RN8T@1236|Gammaproteobacteria,1XTP1@135623|Vibrionales	135623|Vibrionales	K	transcriptional	cytR	-	-	ko:K05499	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
k141_4955_5	796620.VIBC2010_03397	2.45e-73	226.0	COG3087@1|root,COG3087@2|Bacteria,1PWIT@1224|Proteobacteria,1RNC1@1236|Gammaproteobacteria,1XVV0@135623|Vibrionales	135623|Vibrionales	D	cell division protein	ftsN	-	-	ko:K03591	-	-	-	-	ko00000,ko03036	-	-	-	SPOR
k141_847_4	1197477.IA57_08015	1.93e-19	86.7	COG0057@1|root,COG0057@2|Bacteria,4NEMF@976|Bacteroidetes,1HXVU@117743|Flavobacteriia	976|Bacteroidetes	G	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	gap	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
k141_2282_1	551275.KB899547_gene447	1.49e-28	105.0	COG0346@1|root,COG0346@2|Bacteria,1RGZ8@1224|Proteobacteria,2U9J8@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	ko:K08234	-	-	-	-	ko00000	-	-	-	Glyoxalase
k141_2282_2	439235.Dalk_2260	2.17e-20	89.7	COG1433@1|root,COG1433@2|Bacteria,1NKUY@1224|Proteobacteria,42XKV@68525|delta/epsilon subdivisions,2WSWQ@28221|Deltaproteobacteria,2MM9Y@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Dinitrogenase iron-molybdenum cofactor	-	-	-	-	-	-	-	-	-	-	-	-	Nitro_FeMo-Co
k141_2282_4	1121459.AQXE01000008_gene804	3.87e-26	101.0	COG1433@1|root,COG1433@2|Bacteria,1MZ77@1224|Proteobacteria,42U3G@68525|delta/epsilon subdivisions,2WQ5N@28221|Deltaproteobacteria,2MB0I@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	PFAM Dinitrogenase iron-molybdenum cofactor biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	Nitro_FeMo-Co
k141_2282_5	158189.SpiBuddy_0539	3.41e-11	64.3	COG1578@1|root,COG1578@2|Bacteria,2JAEA@203691|Spirochaetes	203691|Spirochaetes	S	Protein of unknown function DUF89	-	-	-	ko:K09116	-	-	-	-	ko00000	-	-	-	DUF89
k141_3949_1	1121904.ARBP01000006_gene3798	6.16e-36	137.0	2FCEE@1|root,344HX@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF3592
k141_3949_2	944480.ATUV01000002_gene437	4.54e-32	125.0	COG1538@1|root,COG1538@2|Bacteria,1PTZ6@1224|Proteobacteria,42RK2@68525|delta/epsilon subdivisions,2WNMB@28221|Deltaproteobacteria,2M70F@213113|Desulfurellales	28221|Deltaproteobacteria	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
k141_321_1	55601.VANGNB10_cI0950	1.29e-122	362.0	COG0349@1|root,COG0349@2|Bacteria,1MURV@1224|Proteobacteria,1RPBP@1236|Gammaproteobacteria,1XSSU@135623|Vibrionales	135623|Vibrionales	J	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides	rnd	-	3.1.13.5	ko:K03684	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DNA_pol_A_exo1,HRDC
k141_321_2	870967.VIS19158_09432	4.21e-44	144.0	COG0851@1|root,COG0851@2|Bacteria,1N6QD@1224|Proteobacteria,1SC8W@1236|Gammaproteobacteria,1XXVX@135623|Vibrionales	135623|Vibrionales	D	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell	minE	-	-	ko:K03608	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	MinE
k141_321_3	675813.VIB_000883	1.24e-170	479.0	COG2894@1|root,COG2894@2|Bacteria,1MUEU@1224|Proteobacteria,1RNJ0@1236|Gammaproteobacteria,1XTBF@135623|Vibrionales	135623|Vibrionales	D	Belongs to the ParA family	minD	-	-	ko:K03609	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31,CbiA
k141_321_4	674977.VMC_34050	6.63e-109	318.0	COG0850@1|root,COG0850@2|Bacteria,1RE6K@1224|Proteobacteria,1T0SI@1236|Gammaproteobacteria,1XTUT@135623|Vibrionales	135623|Vibrionales	D	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization	minC	-	-	ko:K03610	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	MinC_C,MinC_N
k141_321_5	1219065.VPR01S_02_02230	6.17e-40	134.0	COG3100@1|root,COG3100@2|Bacteria,1N83J@1224|Proteobacteria,1SCCD@1236|Gammaproteobacteria,1XYIW@135623|Vibrionales	135623|Vibrionales	S	YcgL domain-containing protein	ycgL	-	-	ko:K09902	-	-	-	-	ko00000	-	-	-	YcgL
k141_321_6	345073.VC395_2071	8.67e-168	476.0	COG2951@1|root,COG2951@2|Bacteria,1MUZ3@1224|Proteobacteria,1RMQ6@1236|Gammaproteobacteria,1XTUP@135623|Vibrionales	135623|Vibrionales	M	Membrane-bound lytic murein transglycosylase B	mltB	-	-	ko:K08305	-	-	-	-	ko00000,ko01000,ko01011	-	GH103	-	SLT_2
k141_321_7	1219065.VPR01S_02_02270	2.23e-167	472.0	COG0190@1|root,COG0190@2|Bacteria,1MWU4@1224|Proteobacteria,1RNSW@1236|Gammaproteobacteria,1XTV0@135623|Vibrionales	135623|Vibrionales	F	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	GO:0003674,GO:0003824,GO:0004477,GO:0004486,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0019752,GO:0034641,GO:0042558,GO:0043436,GO:0043603,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0055114,GO:0071704,GO:1901360,GO:1901564	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
k141_321_8	675816.VIA_000764	9.34e-64	201.0	COG1309@1|root,COG1309@2|Bacteria,1QIZJ@1224|Proteobacteria,1SAGK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
k141_321_9	1348635.BBJY01000005_gene3138	2.96e-86	259.0	COG2249@1|root,COG2249@2|Bacteria,1RA5X@1224|Proteobacteria,1S3UT@1236|Gammaproteobacteria,1XWHN@135623|Vibrionales	135623|Vibrionales	S	NADPH-quinone reductase (modulator of drug activity B)	-	-	-	-	-	-	-	-	-	-	-	-	Flavodoxin_2
k141_321_10	710243.XP_007600126.1	1.18e-23	105.0	2EDXS@1|root,2SJFU@2759|Eukaryota,3AI4J@33154|Opisthokonta,3PCJH@4751|Fungi,3QW4W@4890|Ascomycota,21ERE@147550|Sordariomycetes,1F2G3@1028384|Glomerellales	4751|Fungi	S	NAD(P)H-binding	-	-	-	-	-	-	-	-	-	-	-	-	NmrA
k141_321_11	595494.Tola_0316	3.16e-116	345.0	COG1275@1|root,COG1275@2|Bacteria,1MVPG@1224|Proteobacteria,1RPVM@1236|Gammaproteobacteria,1Y6DM@135624|Aeromonadales	135624|Aeromonadales	P	Voltage-dependent anion channel	-	-	-	ko:K03304	-	-	-	-	ko00000,ko02000	2.A.16.1	-	-	SLAC1
k141_321_12	34007.IT40_24535	3.89e-75	237.0	COG2207@1|root,COG2207@2|Bacteria,1P1FH@1224|Proteobacteria,2TRGB@28211|Alphaproteobacteria,2PWZ3@265|Paracoccus	28211|Alphaproteobacteria	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
k141_321_13	575788.VS_II0078	4.62e-107	323.0	COG0673@1|root,COG0673@2|Bacteria,1MZIG@1224|Proteobacteria,1RS5T@1236|Gammaproteobacteria,1XSQ5@135623|Vibrionales	135623|Vibrionales	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
k141_2847_1	203275.BFO_2581	2.25e-38	148.0	COG5585@1|root,COG5585@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K11044	-	-	-	-	ko00000,ko01000,ko02042	-	-	-	ADPrib_exo_Tox,AHH,PT-TG
k141_2847_3	1517682.HW49_10205	1.73e-26	108.0	COG0457@1|root,COG0457@2|Bacteria,4NV0M@976|Bacteroidetes,2FUD1@200643|Bacteroidia	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_2,TPR_8
k141_2847_4	1430331.EP10_18000	1.13e-40	150.0	COG5585@1|root,COG5585@2|Bacteria,1V80F@1239|Firmicutes,4HJQD@91061|Bacilli	91061|Bacilli	T	COG3209 Rhs family protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_2847_5	1196324.A374_01509	4.88e-37	131.0	2E36E@1|root,32Y65@2|Bacteria,1VHZX@1239|Firmicutes,4HN2V@91061|Bacilli	91061|Bacilli	S	Immunity protein 30	-	-	-	-	-	-	-	-	-	-	-	-	Imm30
k141_1952_1	1121451.DESAM_20079	3.43e-287	793.0	COG0554@1|root,COG0554@2|Bacteria,1MUP7@1224|Proteobacteria,42M9Z@68525|delta/epsilon subdivisions,2WIYZ@28221|Deltaproteobacteria,2M977@213115|Desulfovibrionales	28221|Deltaproteobacteria	F	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate	glpK	GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615	2.7.1.30	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	-	R00847	RC00002,RC00017	ko00000,ko00001,ko01000,ko04147	-	-	-	FGGY_C,FGGY_N
k141_1952_2	986075.CathTA2_1668	2.37e-126	365.0	COG0580@1|root,COG0580@2|Bacteria,1TP4T@1239|Firmicutes,4HAWP@91061|Bacilli	91061|Bacilli	U	Belongs to the MIP aquaporin (TC 1.A.8) family	glpF	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K02440	-	-	-	-	ko00000,ko02000	1.A.8.1,1.A.8.2	-	-	MIP
k141_1952_3	1265505.ATUG01000002_gene2258	1.14e-132	396.0	COG3075@1|root,COG3075@2|Bacteria,1MU3K@1224|Proteobacteria,42Q09@68525|delta/epsilon subdivisions,2WKE0@28221|Deltaproteobacteria,2MJI8@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Anaerobic glycerol-3-phosphate dehydrogenase, subunit	glpB	-	1.1.5.3	ko:K00112	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	FAD_binding_2
k141_1952_4	1265505.ATUG01000002_gene2259	2.16e-244	686.0	COG0578@1|root,COG0578@2|Bacteria,1MUMY@1224|Proteobacteria,42M8D@68525|delta/epsilon subdivisions,2WJ6E@28221|Deltaproteobacteria,2MIEK@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family	glpA	-	1.1.5.3	ko:K00111	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	DAO,DAO_C,Fer2_BFD
k141_1952_5	526222.Desal_3154	1.28e-107	320.0	COG1349@1|root,COG1349@2|Bacteria,1MUJG@1224|Proteobacteria,42NKC@68525|delta/epsilon subdivisions,2WM06@28221|Deltaproteobacteria,2MAS0@213115|Desulfovibrionales	28221|Deltaproteobacteria	K	Transcriptional regulator, DeoR	glpR	-	-	ko:K02444	-	-	-	-	ko00000,ko03000	-	-	-	DeoRC,HTH_DeoR
k141_603_1	717772.THIAE_04355	2.95e-13	68.9	COG2244@1|root,COG2244@2|Bacteria,1R9I0@1224|Proteobacteria,1RP3V@1236|Gammaproteobacteria,461K4@72273|Thiotrichales	72273|Thiotrichales	S	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt_3,Polysacc_synt_C
k141_603_2	883126.HMPREF9710_03498	9.21e-100	293.0	COG1670@1|root,COG1670@2|Bacteria	2|Bacteria	J	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
k141_603_3	883126.HMPREF9710_03497	2.1e-10	62.0	COG0399@1|root,COG0399@2|Bacteria,1R5SK@1224|Proteobacteria,2VYXY@28216|Betaproteobacteria	28216|Betaproteobacteria	M	UDP-4-amino-4-deoxy-L-arabinose aminotransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_3653_1	1304284.L21TH_2027	2.44e-12	68.6	COG0778@1|root,COG0778@2|Bacteria,1V31B@1239|Firmicutes,25B41@186801|Clostridia,36IQM@31979|Clostridiaceae	186801|Clostridia	C	nitroreductase	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
k141_3653_2	96561.Dole_2142	1.18e-51	173.0	COG2129@1|root,COG2129@2|Bacteria,1RJJX@1224|Proteobacteria,42T2C@68525|delta/epsilon subdivisions,2WP7Q@28221|Deltaproteobacteria,2MQ17@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Metallophosphoesterase, calcineurin superfamily	-	-	-	ko:K07096	-	-	-	-	ko00000	-	-	-	Metallophos,Metallophos_2,Metallophos_3
k141_3653_3	179408.Osc7112_0368	1.7e-26	109.0	COG0664@1|root,COG0664@2|Bacteria,1G3SU@1117|Cyanobacteria,1H8VY@1150|Oscillatoriales	1117|Cyanobacteria	K	Cyclic nucleotide-binding domain	-	-	-	ko:K21563	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
k141_3950_1	909663.KI867150_gene1371	8.23e-71	246.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MC4@68525|delta/epsilon subdivisions,2WIZU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg,dCache_1
k141_3654_1	879212.DespoDRAFT_03612	2.35e-98	296.0	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,42MSR@68525|delta/epsilon subdivisions,2WIXG@28221|Deltaproteobacteria,2MI9F@213118|Desulfobacterales	28221|Deltaproteobacteria	I	Belongs to the thiolase family	bamN	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
k141_3246_1	870967.VIS19158_08418	4.46e-196	558.0	COG0534@1|root,COG0534@2|Bacteria,1MUAM@1224|Proteobacteria,1RP5M@1236|Gammaproteobacteria,1XUSY@135623|Vibrionales	135623|Vibrionales	V	Multidrug efflux pump	norM	GO:0003674,GO:0005215,GO:0006810,GO:0006855,GO:0008150,GO:0015238,GO:0015893,GO:0022857,GO:0042221,GO:0042493,GO:0042891,GO:0042895,GO:0046677,GO:0050896,GO:0051179,GO:0051234,GO:0055085	-	ko:K03327	-	-	-	-	ko00000,ko02000	2.A.66.1	-	-	MatE
k141_3246_2	1219076.N646_0537	3.93e-08	53.5	COG0307@1|root,COG0307@2|Bacteria,1MUMB@1224|Proteobacteria,1RMSY@1236|Gammaproteobacteria,1XT06@135623|Vibrionales	135623|Vibrionales	H	Riboflavin synthase alpha chain	ribE	-	2.5.1.9	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00066	RC00958,RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	Lum_binding
k141_2284_1	1304885.AUEY01000004_gene1014	1.11e-71	225.0	COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,42NF6@68525|delta/epsilon subdivisions,2WKVH@28221|Deltaproteobacteria,2MI4N@213118|Desulfobacterales	28221|Deltaproteobacteria	V	PFAM ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
k141_2284_2	608538.HTH_0285	4.2e-20	99.0	COG1333@1|root,COG1333@2|Bacteria,2G400@200783|Aquificae	200783|Aquificae	O	ResB family	-	-	-	ko:K07399	-	-	-	-	ko00000	-	-	-	ResB
k141_2849_2	439235.Dalk_1464	8.59e-43	152.0	COG3385@1|root,COG3385@2|Bacteria,1PMXF@1224|Proteobacteria,43B8Z@68525|delta/epsilon subdivisions,2X6NB@28221|Deltaproteobacteria,2MPI8@213118|Desulfobacterales	1224|Proteobacteria	L	PFAM transposase IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DUF4372
k141_605_1	1348635.BBJY01000003_gene3749	9.57e-96	287.0	COG0428@1|root,COG0428@2|Bacteria,1MWEZ@1224|Proteobacteria,1RNXU@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	Mediates zinc uptake. May also transport other divalent cations	zupT	GO:0000041,GO:0003674,GO:0005215,GO:0005381,GO:0005384,GO:0005385,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006824,GO:0006826,GO:0006828,GO:0006829,GO:0008150,GO:0008324,GO:0015075,GO:0015086,GO:0015087,GO:0015093,GO:0015318,GO:0015684,GO:0015691,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0034755,GO:0044464,GO:0046873,GO:0046915,GO:0051179,GO:0051234,GO:0055085,GO:0070574,GO:0070838,GO:0071421,GO:0071577,GO:0071944,GO:0072509,GO:0072511,GO:0098655,GO:0098660,GO:0098662,GO:1903874	-	ko:K07238	-	-	-	-	ko00000,ko02000	2.A.5.5	-	iECIAI39_1322.ECIAI39_3536	Zip
k141_605_2	1004785.AMBLS11_03805	1.97e-38	149.0	COG0642@1|root,COG2205@2|Bacteria,1QYSY@1224|Proteobacteria,1T3T7@1236|Gammaproteobacteria,46ABC@72275|Alteromonadaceae	1236|Gammaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	2CSK_N,HATPase_c,HisKA
k141_5241_1	1304885.AUEY01000005_gene797	2.19e-48	179.0	COG2385@1|root,COG2385@2|Bacteria,1RGJS@1224|Proteobacteria,42RZE@68525|delta/epsilon subdivisions,2WNH8@28221|Deltaproteobacteria,2MN9B@213118|Desulfobacterales	28221|Deltaproteobacteria	D	Stage II sporulation protein	-	-	-	ko:K06381	-	-	-	-	ko00000	-	-	-	SpoIID,TPR_6,TPR_8
k141_5241_2	1304885.AUEY01000022_gene3417	5.31e-217	606.0	COG0192@1|root,COG0192@2|Bacteria,1MUFQ@1224|Proteobacteria,42MFM@68525|delta/epsilon subdivisions,2WIQ3@28221|Deltaproteobacteria,2MHVQ@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
k141_5241_3	632292.Calhy_0805	2.07e-84	259.0	COG0414@1|root,COG0414@2|Bacteria,1TP7A@1239|Firmicutes,248AN@186801|Clostridia,42F66@68295|Thermoanaerobacterales	186801|Clostridia	H	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate	panC	-	6.3.2.1	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R02473	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_ligase
k141_2285_1	1167006.UWK_01216	4.95e-66	227.0	COG1033@1|root,COG1033@2|Bacteria,1MUE1@1224|Proteobacteria,42ME2@68525|delta/epsilon subdivisions,2WJRI@28221|Deltaproteobacteria,2MJQ7@213118|Desulfobacterales	28221|Deltaproteobacteria	K	MMPL family	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
k141_1955_1	672.VV93_v1c31100	6.57e-45	162.0	COG1283@1|root,COG1283@2|Bacteria,1MUDE@1224|Proteobacteria,1RNMM@1236|Gammaproteobacteria,1XY40@135623|Vibrionales	135623|Vibrionales	P	Na+/Pi-cotransporter	-	-	-	ko:K03324	-	-	-	-	ko00000,ko02000	2.A.58.2	-	-	Na_Pi_cotrans,PhoU
k141_1955_2	1117318.PRUB_12226	4.09e-19	79.7	COG3313@1|root,COG3313@2|Bacteria,1QGVR@1224|Proteobacteria,1TEBS@1236|Gammaproteobacteria,2Q3PD@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	S	Fe-S protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF1289
k141_1955_3	553385.JEMF01000043_gene1687	1.04e-120	353.0	COG3621@1|root,COG3621@2|Bacteria,1RDY7@1224|Proteobacteria,1RSC7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Patatin-like phospholipase	-	-	-	ko:K06900	-	-	-	-	ko00000	-	-	-	Patatin
k141_848_1	1304885.AUEY01000020_gene3514	1.02e-261	726.0	COG0034@1|root,COG0034@2|Bacteria,1MU0V@1224|Proteobacteria,42MDB@68525|delta/epsilon subdivisions,2WITV@28221|Deltaproteobacteria,2MI1E@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_6,GATase_7,Pribosyltran
k141_848_2	1304885.AUEY01000020_gene3515	2.11e-242	701.0	COG0458@1|root,COG0458@2|Bacteria,1MUDZ@1224|Proteobacteria,42MGK@68525|delta/epsilon subdivisions,2WJQH@28221|Deltaproteobacteria,2MHQD@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Carbamoyl-phosphate synthetase large chain oligomerisation	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
k141_2850_1	1121396.KB892945_gene2891	1.11e-42	147.0	COG2043@1|root,COG2043@2|Bacteria,1R8EH@1224|Proteobacteria,42Q2F@68525|delta/epsilon subdivisions,2WJZN@28221|Deltaproteobacteria,2MKRH@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Uncharacterised ArCR, COG2043	-	-	-	-	-	-	-	-	-	-	-	-	DUF169
k141_4281_1	1499967.BAYZ01000089_gene5012	4.63e-52	169.0	2BQ07@1|root,32IUB@2|Bacteria	2|Bacteria	S	Putative redox-active protein (C_GCAxxG_C_C)	-	-	-	-	-	-	-	-	-	-	-	-	C_GCAxxG_C_C
k141_4281_2	517418.Ctha_2501	8.72e-21	89.7	2A0R5@1|root,334I1@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_4655_1	1136163.M565_ctg5P0858	2.45e-14	70.5	COG0302@1|root,COG0302@2|Bacteria,1MY3N@1224|Proteobacteria,1RMQM@1236|Gammaproteobacteria,1XUKF@135623|Vibrionales	135623|Vibrionales	F	GTP cyclohydrolase	folE	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006082,GO:0006575,GO:0006725,GO:0006729,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0019752,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0043603,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	3.5.4.16	ko:K01495	ko00790,ko01100,map00790,map01100	M00126,M00841,M00842,M00843	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_cyclohydroI
k141_4655_2	672.VV93_v1c40330	5.39e-203	572.0	COG0303@1|root,COG0303@2|Bacteria,1MVD5@1224|Proteobacteria,1RMQU@1236|Gammaproteobacteria,1XSIM@135623|Vibrionales	135623|Vibrionales	H	molybdopterin biosynthesis	moeA	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
k141_4655_3	1191299.AJYX01000099_gene840	1.24e-116	341.0	COG0476@1|root,COG0476@2|Bacteria,1MW7H@1224|Proteobacteria,1RPJ3@1236|Gammaproteobacteria,1XTIB@135623|Vibrionales	135623|Vibrionales	H	COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2	moeB	-	2.7.7.80	ko:K21029	ko04122,map04122	-	R07459	RC00043	ko00000,ko00001,ko01000	-	-	-	ThiF
k141_4655_4	29495.EA26_10505	7.66e-197	550.0	COG2390@1|root,COG2390@2|Bacteria,1MX3F@1224|Proteobacteria,1RMEZ@1236|Gammaproteobacteria,1XT80@135623|Vibrionales	135623|Vibrionales	K	Transcriptional regulator, contains sigma factor-related N-terminal domain	lsrR	-	-	-	-	-	-	-	-	-	-	-	HTH_28,Sugar-bind
k141_4655_5	314292.VAS14_14989	1.26e-186	523.0	COG0176@1|root,COG0176@2|Bacteria,1MWQ8@1224|Proteobacteria,1RMS0@1236|Gammaproteobacteria,1XSNT@135623|Vibrionales	135623|Vibrionales	F	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	tal	GO:0003674,GO:0003824,GO:0004801,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009987,GO:0016740,GO:0016744,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
k141_4655_7	1348635.BBJY01000029_gene2039	3.19e-118	343.0	COG4565@1|root,COG4565@2|Bacteria,1P6VJ@1224|Proteobacteria,1RPI7@1236|Gammaproteobacteria,1Y2MJ@135623|Vibrionales	135623|Vibrionales	K	Transcriptional regulator	-	-	-	ko:K02475,ko:K07702	ko02020,map02020	M00486	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	CitT,Response_reg
k141_4655_8	1348635.BBJY01000029_gene2040	1.97e-259	726.0	COG3290@1|root,COG3290@2|Bacteria,1MXQ5@1224|Proteobacteria,1RNRF@1236|Gammaproteobacteria,1XSAU@135623|Vibrionales	1236|Gammaproteobacteria	T	COG3290 Signal transduction histidine kinase regulating citrate malate metabolism	dpiB	GO:0000155,GO:0000160,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009987,GO:0010033,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0035556,GO:0036211,GO:0042221,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0070887,GO:0071310,GO:0071704,GO:0071944,GO:0140096,GO:1901564	2.7.13.3	ko:K07700	ko02020,map02020	M00486	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,PAS,PAS_8,SPOB_a,sCache_3_2
k141_4655_9	1348635.BBJY01000029_gene2041	0.0	1335.0	COG1049@1|root,COG1049@2|Bacteria,1MVCR@1224|Proteobacteria,1RNMC@1236|Gammaproteobacteria,1XTKU@135623|Vibrionales	1236|Gammaproteobacteria	C	Belongs to the aconitase IPM isomerase family	acnB	-	4.2.1.3,4.2.1.99	ko:K01682	ko00020,ko00630,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173	R01324,R01325,R01900,R04425	RC00497,RC00498,RC00618,RC01153	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_2_N,Aconitase_B_N
k141_4655_10	1348635.BBJY01000029_gene2042	2.62e-272	750.0	COG2851@1|root,COG2851@2|Bacteria,1N25B@1224|Proteobacteria,1RR4W@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Citrate transporter	-	-	-	ko:K03300	-	-	-	-	ko00000	2.A.11	-	-	CitMHS
k141_4655_12	223926.28806938	0.0	1226.0	COG0417@1|root,COG0417@2|Bacteria,1MVY9@1224|Proteobacteria,1RMQ1@1236|Gammaproteobacteria,1XTIT@135623|Vibrionales	135623|Vibrionales	L	COG0417 DNA polymerase elongation subunit (family B)	polB	-	2.7.7.7	ko:K02336	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_pol_B,DNA_pol_B_exo1
k141_4655_14	273526.SMDB11_2956	2.2e-293	800.0	COG4948@1|root,COG4948@2|Bacteria,1MURK@1224|Proteobacteria,1RNRB@1236|Gammaproteobacteria,401ID@613|Serratia	1236|Gammaproteobacteria	M	Belongs to the mandelate racemase muconate lactonizing enzyme family	rspA	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005975,GO:0008150,GO:0008152,GO:0008927,GO:0009056,GO:0016052,GO:0016829,GO:0016835,GO:0016836,GO:0043167,GO:0043169,GO:0044238,GO:0046872,GO:0047929,GO:0071704,GO:1901575	4.2.1.8	ko:K08323	ko00040,ko01100,map00040,map01100	M00061	R05606	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
k141_4655_15	1453496.AT03_16165	1.29e-60	197.0	COG1802@1|root,COG1802@2|Bacteria,1MWG2@1224|Proteobacteria,1RNYJ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	transcriptional regulator	ydfH	-	-	ko:K22293	-	-	-	-	ko00000,ko03000	-	-	-	FCD,GntR
k141_4655_16	314292.VAS14_04898	6.31e-18	76.3	2EK1G@1|root,33DRY@2|Bacteria,1NH6C@1224|Proteobacteria,1SGMZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF3012)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3012
k141_2650_5	1219065.VPR01S_04_02860	1.23e-123	365.0	COG3156@1|root,COG3156@2|Bacteria,1RC9P@1224|Proteobacteria,1T072@1236|Gammaproteobacteria,1XT6W@135623|Vibrionales	135623|Vibrionales	U	COG3156 Type II secretory pathway, component PulK	epsK	-	-	ko:K02460	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSK
k141_2650_6	1116375.VEJY3_00650	1.16e-79	258.0	COG3297@1|root,COG3297@2|Bacteria,1NVVW@1224|Proteobacteria,1S01F@1236|Gammaproteobacteria,1XUFK@135623|Vibrionales	135623|Vibrionales	U	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins	gspL	GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705	-	ko:K02461	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	GspL_C,T2SSL
k141_2650_7	672.VV93_v1c02050	3.98e-38	135.0	COG3149@1|root,COG3149@2|Bacteria,1N8VZ@1224|Proteobacteria,1S8X3@1236|Gammaproteobacteria,1XU6P@135623|Vibrionales	135623|Vibrionales	U	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins	epsM	GO:0008150,GO:0009405,GO:0044419,GO:0051704	-	ko:K02462	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSM
k141_2650_9	1117315.AHCA01000001_gene2400	6.29e-131	382.0	COG0330@1|root,COG0330@2|Bacteria,1MUM8@1224|Proteobacteria,1RNW8@1236|Gammaproteobacteria,2PZW3@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	O	COG0330 Membrane protease subunits, stomatin prohibitin homologs	qmcA	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Band_7,Band_7_C
k141_2650_10	1188252.AJYK01000023_gene1498	3.64e-39	137.0	COG1585@1|root,COG1585@2|Bacteria,1N1IY@1224|Proteobacteria,1S97A@1236|Gammaproteobacteria,1XZ1X@135623|Vibrionales	135623|Vibrionales	OU	NfeD-like C-terminal, partner-binding	-	-	-	ko:K07340	-	-	-	-	ko00000	-	-	-	NfeD
k141_2650_11	675814.VIC_003651	6.11e-173	486.0	COG0720@1|root,COG0720@2|Bacteria,1MXVT@1224|Proteobacteria,1RN6H@1236|Gammaproteobacteria,1XU54@135623|Vibrionales	135623|Vibrionales	H	COG0720 6-pyruvoyl-tetrahydropterin synthase	SO2179	-	-	-	-	-	-	-	-	-	-	-	PTPS
k141_4365_2	1304885.AUEY01000025_gene2758	3.77e-188	570.0	COG1344@1|root,COG1344@2|Bacteria,1MV1N@1224|Proteobacteria,42MX8@68525|delta/epsilon subdivisions,2WJRC@28221|Deltaproteobacteria,2MISQ@213118|Desulfobacterales	28221|Deltaproteobacteria	N	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella	-	-	-	ko:K02406	ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flagellin_C,Flagellin_IN,Flagellin_N
k141_1359_4	511680.BUTYVIB_00032	3.19e-64	206.0	COG0745@1|root,COG0745@2|Bacteria,1TPZ0@1239|Firmicutes,2484X@186801|Clostridia,4BXVM@830|Butyrivibrio	186801|Clostridia	T	Transcriptional regulatory protein, C terminal	srrA_6	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
k141_1359_5	332101.JIBU02000009_gene763	1.01e-81	273.0	COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,247VG@186801|Clostridia,36DKF@31979|Clostridiaceae	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
k141_1638_1	1122921.KB898186_gene5048	1.57e-74	245.0	COG1263@1|root,COG1264@1|root,COG2190@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,COG2190@2|Bacteria,1TP5X@1239|Firmicutes,4HA0I@91061|Bacilli,26QAW@186822|Paenibacillaceae	91061|Bacilli	G	COG1264 Phosphotransferase system IIB components	arbF1	-	-	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	M00271	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.1.2.11,4.A.1.2.2,4.A.1.2.5,4.A.1.2.6	-	-	PTS_EIIA_1,PTS_EIIB,PTS_EIIC
k141_1639_1	1122927.KB895419_gene2561	7.57e-05	45.8	COG0746@1|root,COG0746@2|Bacteria,1VA6T@1239|Firmicutes,4HK1H@91061|Bacilli,26YMP@186822|Paenibacillaceae	91061|Bacilli	H	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor	mobA	-	2.7.7.77	ko:K03752	ko00790,ko01100,map00790,map01100	-	R11581	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
k141_1639_2	1304885.AUEY01000025_gene2768	1.79e-65	219.0	COG0243@1|root,COG0243@2|Bacteria,1NR6J@1224|Proteobacteria,42NEV@68525|delta/epsilon subdivisions,2WJD0@28221|Deltaproteobacteria,2MMR0@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Molybdopterin oxidoreductase Fe4S4 domain	-	-	-	-	-	-	-	-	-	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
k141_1361_1	123899.JPQP01000001_gene1740	1.84e-16	82.8	COG0477@1|root,COG2814@2|Bacteria,1QTY0@1224|Proteobacteria,2WGHA@28216|Betaproteobacteria,3T36K@506|Alcaligenaceae	28216|Betaproteobacteria	U	the major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
k141_2652_2	1217656.F964_00661	2.93e-21	101.0	COG3103@1|root,COG3103@2|Bacteria,1R4IV@1224|Proteobacteria,1RYIZ@1236|Gammaproteobacteria,3NJSP@468|Moraxellaceae	1236|Gammaproteobacteria	T	Sh3 type 3 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Phenol_MetA_deg
k141_5322_1	665950.HMPREF1025_01084	4.05e-89	273.0	COG0253@1|root,COG0253@2|Bacteria,1TPMN@1239|Firmicutes,24AGY@186801|Clostridia,27IKY@186928|unclassified Lachnospiraceae	186801|Clostridia	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	dapF	-	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	DAP_epimerase
k141_5322_2	742738.HMPREF9460_02194	5.51e-61	202.0	COG1509@1|root,COG1509@2|Bacteria,1TQQZ@1239|Firmicutes,249JV@186801|Clostridia,267R9@186813|unclassified Clostridiales	186801|Clostridia	E	Lysine-2,3-aminomutase	kamA	-	5.4.3.2,5.4.3.9	ko:K01843,ko:K19814	ko00310,map00310	-	R00461	RC00303	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Fer4_14,LAM_C,Radical_SAM
k141_1642_1	888055.HMPREF9015_00234	1.34e-22	97.1	COG1263@1|root,COG1264@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,378EF@32066|Fusobacteria	32066|Fusobacteria	G	K02749 PTS system, arbutin-like IIB component K02750	glvC	-	2.7.1.208	ko:K02749,ko:K02750	ko00500,ko02060,map00500,map02060	M00268	R04111	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.1.1.10,4.A.1.1.16,4.A.1.1.4,4.A.1.1.8	-	-	PTS_EIIB,PTS_EIIC
k141_4367_1	1219077.VAZ01S_044_00320	2.39e-85	255.0	COG1959@1|root,COG1959@2|Bacteria,1RDA4@1224|Proteobacteria,1S3RW@1236|Gammaproteobacteria,1XTCH@135623|Vibrionales	135623|Vibrionales	K	Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins	iscR	-	-	ko:K13643	-	-	-	-	ko00000,ko03000	-	-	-	Rrf2
k141_4367_2	1219065.VPR01S_10_01280	2.74e-126	367.0	COG0565@1|root,COG0565@2|Bacteria,1N47Y@1224|Proteobacteria,1RPD3@1236|Gammaproteobacteria,1XSWM@135623|Vibrionales	135623|Vibrionales	J	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA	trmJ	-	2.1.1.200	ko:K15396	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
k141_2654_1	1201290.M902_0876	3.95e-70	228.0	COG3634@1|root,COG3634@2|Bacteria,1MUKD@1224|Proteobacteria,42P04@68525|delta/epsilon subdivisions,2MTQR@213481|Bdellovibrionales,2WMFA@28221|Deltaproteobacteria	213481|Bdellovibrionales	O	Pyridine nucleotide-disulphide oxidoreductase	ahpF	-	-	ko:K03387	-	-	-	-	ko00000,ko01000	-	-	-	Pyr_redox_2,Thioredoxin_3
k141_2654_2	1201290.M902_0875	1.46e-117	338.0	COG0450@1|root,COG0450@2|Bacteria,1MWPY@1224|Proteobacteria,42MAJ@68525|delta/epsilon subdivisions,2MTMU@213481|Bdellovibrionales,2WN6W@28221|Deltaproteobacteria	213481|Bdellovibrionales	O	C-terminal domain of 1-Cys peroxiredoxin	ahpC	-	1.11.1.15	ko:K03386	ko04214,map04214	-	-	-	ko00000,ko00001,ko01000,ko04147	-	-	-	1-cysPrx_C,AhpC-TSA
k141_1643_1	489825.LYNGBM3L_74510	6.14e-150	479.0	COG1020@1|root,COG3321@1|root,COG1020@2|Bacteria,COG3321@2|Bacteria,1FZXE@1117|Cyanobacteria,1H927@1150|Oscillatoriales	1117|Cyanobacteria	Q	Acyl transferase domain in polyketide synthase (PKS) enzymes.	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,AMP-binding,AMP-binding_C,Acyl_transf_1,Condensation,ECH_1,KAsynt_C_assoc,Ketoacyl-synt_C,PP-binding,Thioesterase,ketoacyl-synt
k141_5323_1	1304885.AUEY01000007_gene1363	1.48e-270	795.0	COG1924@1|root,COG3580@1|root,COG3581@1|root,COG1924@2|Bacteria,COG3580@2|Bacteria,COG3581@2|Bacteria,1PKG6@1224|Proteobacteria,42MY4@68525|delta/epsilon subdivisions,2WJFI@28221|Deltaproteobacteria,2MIP0@213118|Desulfobacterales	28221|Deltaproteobacteria	I	BadF BadG BcrA BcrD	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG,DUF2229
k141_4063_1	65393.PCC7424_1545	6.54e-60	198.0	COG0313@1|root,COG0313@2|Bacteria,1G0IF@1117|Cyanobacteria,3KFU7@43988|Cyanothece	1117|Cyanobacteria	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA	rsmI	GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
k141_4063_2	1392493.JIAB01000001_gene295	5.04e-15	73.2	COG0792@1|root,COG0792@2|Bacteria,1VFHQ@1239|Firmicutes,24QNK@186801|Clostridia,27PPJ@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Uncharacterised protein family UPF0102	-	-	-	ko:K07460	-	-	-	-	ko00000	-	-	-	UPF0102
k141_4063_3	574087.Acear_1661	2.32e-55	185.0	COG0164@1|root,COG0164@2|Bacteria,1V1D6@1239|Firmicutes,248IT@186801|Clostridia,3WAMH@53433|Halanaerobiales	186801|Clostridia	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhB	-	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
k141_4063_4	1121405.dsmv_2124	1.36e-47	155.0	COG0335@1|root,COG0335@2|Bacteria,1RH3A@1224|Proteobacteria,42TMU@68525|delta/epsilon subdivisions,2WQ67@28221|Deltaproteobacteria,2MK6N@213118|Desulfobacterales	28221|Deltaproteobacteria	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	rplS	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
k141_4063_5	177439.DP2804	3.39e-51	171.0	COG4752@1|root,COG4752@2|Bacteria,1RJ2G@1224|Proteobacteria,42SXX@68525|delta/epsilon subdivisions,2WP1I@28221|Deltaproteobacteria,2MJZA@213118|Desulfobacterales	28221|Deltaproteobacteria	S	SAM-dependent RNA methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltrn_RNA_4
k141_4063_6	1304885.AUEY01000005_gene809	1.22e-85	262.0	COG0336@1|root,COG0336@2|Bacteria,1MUN1@1224|Proteobacteria,42P8R@68525|delta/epsilon subdivisions,2WKIR@28221|Deltaproteobacteria,2MIUI@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Belongs to the RNA methyltransferase TrmD family	trmD	GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	Methyltrn_RNA_4,tRNA_m1G_MT
k141_4063_7	632245.CLP_2532	3.12e-19	87.0	COG0806@1|root,COG0806@2|Bacteria,1V6HD@1239|Firmicutes,24I1G@186801|Clostridia,36IPC@31979|Clostridiaceae	186801|Clostridia	J	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes	rimM	-	-	ko:K02860	-	-	-	-	ko00000,ko03009	-	-	-	PRC,RimM
k141_4063_8	933262.AXAM01000016_gene160	1.37e-35	122.0	COG1837@1|root,COG1837@2|Bacteria,1N7IX@1224|Proteobacteria,42TXI@68525|delta/epsilon subdivisions,2WQBS@28221|Deltaproteobacteria,2MKI6@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Belongs to the UPF0109 family	-	-	-	ko:K06960	-	-	-	-	ko00000	-	-	-	KH_4
k141_4063_9	203120.LEUM_1485	8.59e-32	114.0	COG0228@1|root,COG0228@2|Bacteria,1VA0X@1239|Firmicutes,4HKNN@91061|Bacilli,4AXVF@81850|Leuconostocaceae	91061|Bacilli	J	Belongs to the bacterial ribosomal protein bS16 family	rpsP	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02959	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S16
k141_4063_10	96561.Dole_2310	1.48e-197	561.0	COG0541@1|root,COG0541@2|Bacteria,1MVIA@1224|Proteobacteria,42M94@68525|delta/epsilon subdivisions,2WINB@28221|Deltaproteobacteria,2MHWE@213118|Desulfobacterales	28221|Deltaproteobacteria	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components	ffh	-	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
k141_4063_11	177437.HRM2_31030	1.71e-134	394.0	COG0820@1|root,COG0820@2|Bacteria,1MUYK@1224|Proteobacteria,42N69@68525|delta/epsilon subdivisions,2WIUJ@28221|Deltaproteobacteria,2MJ4T@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Fer4_14,Radical_SAM
k141_4063_12	96561.Dole_2797	3.6e-97	295.0	COG0301@1|root,COG0301@2|Bacteria,1N1R1@1224|Proteobacteria,42MQ9@68525|delta/epsilon subdivisions,2WJPN@28221|Deltaproteobacteria,2MICH@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Thiamine biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF814,ThiI
k141_2656_1	1190606.AJYG01000085_gene3240	3.86e-35	128.0	COG2145@1|root,COG2145@2|Bacteria,1MVES@1224|Proteobacteria,1RRAE@1236|Gammaproteobacteria,1XSM9@135623|Vibrionales	135623|Vibrionales	H	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)	thiM	-	2.7.1.50	ko:K00878	ko00730,ko01100,map00730,map01100	M00127	R04448	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HK
k141_2656_2	1238450.VIBNISOn1_1260064	9.06e-78	239.0	COG0352@1|root,COG0352@2|Bacteria,1RDSU@1224|Proteobacteria,1RZCF@1236|Gammaproteobacteria,1Y2NF@135623|Vibrionales	135623|Vibrionales	H	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)	thiE	-	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	TMP-TENI
k141_2656_3	396588.Tgr7_0616	2.62e-200	575.0	COG0620@1|root,COG0620@2|Bacteria,1MUI9@1224|Proteobacteria,1RMBA@1236|Gammaproteobacteria,1WWZR@135613|Chromatiales	135613|Chromatiales	E	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation	metE	-	2.1.1.14	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	M00017	R04405,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	Meth_synt_1,Meth_synt_2
k141_4064_1	1265503.KB905176_gene4068	5.98e-11	70.5	COG3283@1|root,COG3283@2|Bacteria,1QTS3@1224|Proteobacteria,1RNAI@1236|Gammaproteobacteria,2Q6FF@267889|Colwelliaceae	1236|Gammaproteobacteria	EK	Sigma-54 interaction domain	tyrR	GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008144,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0017076,GO:0019219,GO:0019222,GO:0030554,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141	-	ko:K03721	-	-	-	-	ko00000,ko03000	-	-	-	PAS,PAS_8,Sigma54_activat
k141_4368_2	1031288.AXAA01000004_gene1919	6.65e-154	449.0	COG0427@1|root,COG0427@2|Bacteria,1TPHC@1239|Firmicutes,247V0@186801|Clostridia,36FHR@31979|Clostridiaceae	186801|Clostridia	C	acetyl-CoA hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	AcetylCoA_hyd_C,AcetylCoA_hydro
k141_4368_3	401526.TcarDRAFT_1842	4.38e-110	348.0	COG3829@1|root,COG3829@2|Bacteria,1TP0E@1239|Firmicutes,4H2QY@909932|Negativicutes	909932|Negativicutes	KT	PFAM sigma-54 factor interaction domain-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CBS,HTH_8,PAS,Sigma54_activat
k141_4369_1	1304885.AUEY01000122_gene640	2.34e-116	351.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,42M51@68525|delta/epsilon subdivisions,2WIPP@28221|Deltaproteobacteria,2MHPE@213118|Desulfobacterales	28221|Deltaproteobacteria	NU	type II secretion system protein E	gspE	-	-	ko:K02454	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSE,T2SSE_N
k141_5325_2	264730.PSPPH_2471	6.48e-124	365.0	COG1957@1|root,COG1957@2|Bacteria,1MYUF@1224|Proteobacteria,1SCF6@1236|Gammaproteobacteria,1Z8B7@136849|Pseudomonas syringae group	1236|Gammaproteobacteria	F	Inosine-uridine preferring nucleoside hydrolase	-	-	3.2.2.1	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	-	R01245,R01273,R01677,R01770,R02143	RC00033,RC00063,RC00122,RC00318,RC00485	ko00000,ko00001,ko01000	-	-	-	IU_nuc_hydro
k141_4065_1	243277.VC_1375	2.78e-77	239.0	2CNUX@1|root,32SHU@2|Bacteria,1REYT@1224|Proteobacteria,1S2ZX@1236|Gammaproteobacteria,1XSGJ@135623|Vibrionales	135623|Vibrionales	S	Domain of unknown function (DUF2760)	VV12320	-	-	-	-	-	-	-	-	-	-	-	DUF2760
k141_1675_19	675817.VDA_000280	0.0	1145.0	COG3383@1|root,COG3383@2|Bacteria,1QTZB@1224|Proteobacteria,1T1JA@1236|Gammaproteobacteria,1Y37S@135623|Vibrionales	135623|Vibrionales	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Fer2_4,Fer4,Fer4_7,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
k141_1675_20	1236542.BALM01000004_gene2334	5.23e-90	268.0	COG1142@1|root,COG1142@2|Bacteria,1PENN@1224|Proteobacteria,1RS57@1236|Gammaproteobacteria,2QDXB@267890|Shewanellaceae	1236|Gammaproteobacteria	C	4Fe-4S binding domain	hydN	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016491,GO:0022900,GO:0044237,GO:0044424,GO:0044464,GO:0055114	-	ko:K00196,ko:K05796	ko00633,ko00680,ko00720,ko01120,ko01200,map00633,map00680,map00720,map01120,map01200	-	R07157,R08034	RC00250,RC02800	ko00000,ko00001	-	-	-	Fer4,Fer4_11,Fer4_3,Fer4_4,Fer4_6,Fer4_7,Fer4_9
k141_1675_21	1454202.PPBDW_100251___1	3.79e-73	223.0	COG0680@1|root,COG0680@2|Bacteria,1R3V7@1224|Proteobacteria,1S0IE@1236|Gammaproteobacteria,1XWDR@135623|Vibrionales	135623|Vibrionales	C	Hydrogenase maturation protease	hycI	-	-	-	-	-	-	-	-	-	-	-	HycI
k141_1675_22	1124991.MU9_3447	1.05e-30	114.0	2DBX5@1|root,2ZBMB@2|Bacteria,1RHQ7@1224|Proteobacteria,1S6TA@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Formate hydrogen-lyase	hyfJ	-	-	ko:K12145	-	-	-	-	ko00000,ko01000	-	-	iECSP_1301.ECSP_3429	HycH
k141_1675_23	675817.VDA_000278	2.61e-142	408.0	COG3260@1|root,COG3260@2|Bacteria,1QUBE@1224|Proteobacteria,1RNUG@1236|Gammaproteobacteria,1XW18@135623|Vibrionales	135623|Vibrionales	C	NADH ubiquinone oxidoreductase, 20 Kd subunit	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_q6
k141_1675_24	1205683.CAKR01000010_gene3410	3.25e-52	172.0	COG1143@1|root,COG1143@2|Bacteria,1R9YT@1224|Proteobacteria,1RQB1@1236|Gammaproteobacteria,41DX5@629|Yersinia	1236|Gammaproteobacteria	C	4Fe-4S binding domain	hyfH	-	-	ko:K12143	-	-	-	-	ko00000	-	-	-	Fer4,Fer4_7
k141_1675_25	314292.VAS14_14279	0.0	1014.0	COG3261@1|root,COG3262@1|root,COG3261@2|Bacteria,COG3262@2|Bacteria,1QUBF@1224|Proteobacteria,1RSJ4@1236|Gammaproteobacteria,1XVAV@135623|Vibrionales	135623|Vibrionales	C	Respiratory-chain NADH dehydrogenase, 30 Kd subunit	-	-	-	-	-	-	-	-	-	-	-	-	Complex1_30kDa,Complex1_49kDa,NiFeSe_Hases
k141_1675_26	630626.EBL_c34570	4.61e-190	549.0	COG0651@1|root,COG0651@2|Bacteria,1MVBA@1224|Proteobacteria,1RPB3@1236|Gammaproteobacteria	1236|Gammaproteobacteria	CP	PFAM NADH Ubiquinone plastoquinone	hyfF	GO:0005575,GO:0005623,GO:0005886,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0031224,GO:0033554,GO:0044425,GO:0044464,GO:0050896,GO:0051716,GO:0071944	-	ko:K12141	-	-	-	-	ko00000,ko01000	-	-	iECIAI39_1322.ECIAI39_2625,iZ_1308.Z3746	Proton_antipo_M,Proton_antipo_N
k141_1675_27	527002.yaldo0001_11200	4.91e-72	225.0	COG4237@1|root,COG4237@2|Bacteria,1NAT8@1224|Proteobacteria,1RRYF@1236|Gammaproteobacteria,41EQM@629|Yersinia	1236|Gammaproteobacteria	C	hydrogenase 4 membrane subunit	hyfE	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K12140	-	-	-	-	ko00000,ko01000	-	-	-	Oxidored_q2
k141_1675_28	1205683.CAKR01000010_gene3406	1.16e-215	611.0	COG1009@1|root,COG1009@2|Bacteria,1MW2M@1224|Proteobacteria,1RY6H@1236|Gammaproteobacteria,41F8T@629|Yersinia	1236|Gammaproteobacteria	CP	to Hydrogenase-4 component D of Bacteria UniRef RepID HYFD_ECOLI	hyfD	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	ko:K12139	-	-	-	-	ko00000,ko01000	-	-	iEcSMS35_1347.EcSMS35_2631	Proton_antipo_M,Proton_antipo_N
k141_1675_29	1236542.BALM01000004_gene2327	1.69e-152	437.0	COG0650@1|root,COG0650@2|Bacteria,1MXV5@1224|Proteobacteria,1RPCY@1236|Gammaproteobacteria,2QEF2@267890|Shewanellaceae	1236|Gammaproteobacteria	C	NADH dehydrogenase	hyfC	GO:0005575,GO:0005623,GO:0005886,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0016020,GO:0033554,GO:0044464,GO:0050896,GO:0051716,GO:0071944	-	ko:K12138,ko:K12139	-	-	-	-	ko00000,ko01000	-	-	iUMNK88_1353.UMNK88_3079	NADHdh
k141_1675_30	314282.PCNPT3_12270	2.23e-279	787.0	COG0651@1|root,COG0651@2|Bacteria,1QU5Z@1224|Proteobacteria,1T20X@1236|Gammaproteobacteria	1236|Gammaproteobacteria	CP	PFAM NADH Ubiquinone plastoquinone (complex I)	-	-	-	ko:K12137	-	-	-	-	ko00000,ko01000	-	-	-	Proton_antipo_M
k141_1675_31	675817.VDA_001171	9.96e-112	325.0	COG1142@1|root,COG1142@2|Bacteria,1MUHW@1224|Proteobacteria,1RQWU@1236|Gammaproteobacteria,1XVYS@135623|Vibrionales	135623|Vibrionales	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_6
k141_2705_1	377629.TERTU_4689	1.06e-120	355.0	COG0583@1|root,COG0583@2|Bacteria,1MUIX@1224|Proteobacteria,1RRF3@1236|Gammaproteobacteria,2PMQF@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	K	LysR substrate binding domain	metR	-	-	ko:K03576	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,LysR_substrate
k141_2705_2	1042375.AFPL01000046_gene1949	4.12e-181	530.0	COG0620@1|root,COG0620@2|Bacteria,1MUI9@1224|Proteobacteria,1RMBA@1236|Gammaproteobacteria,465YA@72275|Alteromonadaceae	1236|Gammaproteobacteria	E	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation	metE	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003871,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006464,GO:0006479,GO:0006520,GO:0006555,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008213,GO:0008276,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0019538,GO:0019752,GO:0032259,GO:0034641,GO:0035999,GO:0036211,GO:0042084,GO:0042085,GO:0042558,GO:0043170,GO:0043412,GO:0043414,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0050667,GO:0051186,GO:0071704,GO:0140096,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.1.1.14	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	M00017	R04405,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	iE2348C_1286.E2348C_4130,iECO103_1326.ECO103_4334,iECO111_1330.ECO111_4657,iECO26_1355.ECO26_4756,iECW_1372.ECW_m4131,iEKO11_1354.EKO11_4528,iPC815.YPO3788,iWFL_1372.ECW_m4131	Meth_synt_1,Meth_synt_2
k141_1015_1	1219065.VPR01S_01_00920	3.58e-96	288.0	COG3148@1|root,COG3148@2|Bacteria,1N8XY@1224|Proteobacteria,1RS6H@1236|Gammaproteobacteria,1XV59@135623|Vibrionales	135623|Vibrionales	S	DTW	-	-	-	ko:K05812	-	-	-	-	ko00000	-	-	-	DTW
k141_1015_2	926690.KE386573_gene2778	1.58e-09	69.7	COG0840@1|root,arCOG02320@2157|Archaea,2XTQ6@28890|Euryarchaeota,23UQ1@183963|Halobacteria	183963|Halobacteria	T	Protoglobin	-	-	-	-	-	-	-	-	-	-	-	-	MCPsignal,Protoglobin
k141_1015_3	1187848.AJYQ01000076_gene1635	2.04e-58	184.0	2B806@1|root,3217S@2|Bacteria,1RHQE@1224|Proteobacteria,1S7AC@1236|Gammaproteobacteria,1XXB8@135623|Vibrionales	135623|Vibrionales	S	COG0187 Type IIA topoisomerase (DNA gyrase topo II, topoisomerase IV), B subunit	SO2891	-	-	-	-	-	-	-	-	-	-	-	DUF3802
k141_1015_4	1238450.VIBNISOn1_1600004	8.84e-112	332.0	COG3001@1|root,COG3001@2|Bacteria,1MVHX@1224|Proteobacteria,1RRC5@1236|Gammaproteobacteria,1XSBA@135623|Vibrionales	135623|Vibrionales	G	COG3001 Fructosamine-3-kinase	-	GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0044237	-	-	-	-	-	-	-	-	-	-	Fructosamin_kin
k141_1015_5	1348635.BBJY01000005_gene3182	9.81e-53	171.0	COG0307@1|root,COG0307@2|Bacteria,1MUMB@1224|Proteobacteria,1RMSY@1236|Gammaproteobacteria,1XT06@135623|Vibrionales	135623|Vibrionales	H	Riboflavin synthase alpha chain	ribE	-	2.5.1.9	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00066	RC00958,RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	Lum_binding
k141_3004_1	675816.VIA_002176	7.84e-227	648.0	COG4590@1|root,COG4590@2|Bacteria,1QTTD@1224|Proteobacteria,1T1GK@1236|Gammaproteobacteria,1XSKV@135623|Vibrionales	135623|Vibrionales	P	phosphate ABC transporter, permease	-	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
k141_3004_2	55601.VANGNB10_cI0646	5.24e-249	701.0	COG0581@1|root,COG0581@2|Bacteria,1MUWB@1224|Proteobacteria,1RPV9@1236|Gammaproteobacteria,1XTB7@135623|Vibrionales	135623|Vibrionales	P	phosphate transport system	pstA	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
k141_3004_4	1280001.BAOA01000085_gene3601	2.72e-130	374.0	COG0704@1|root,COG0704@2|Bacteria,1MUMI@1224|Proteobacteria,1RMW5@1236|Gammaproteobacteria,1XSNM@135623|Vibrionales	135623|Vibrionales	P	Plays a role in the regulation of phosphate uptake	phoU	-	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
k141_3313_1	332101.JIBU02000001_gene4330	6.71e-229	656.0	COG3829@1|root,COG3829@2|Bacteria,1TP0E@1239|Firmicutes,247MB@186801|Clostridia,36DY7@31979|Clostridiaceae	186801|Clostridia	KT	PFAM sigma-54 factor interaction domain-containing protein	-	-	-	ko:K02688	-	-	-	-	ko00000,ko03000	-	-	-	HTH_8,PAS,PAS_4,PAS_8,PAS_9,PrpR_N,Sigma54_activat
k141_1676_1	1304885.AUEY01000001_gene3265	1.7e-102	305.0	COG1352@1|root,COG1352@2|Bacteria,1MU6W@1224|Proteobacteria,42M4H@68525|delta/epsilon subdivisions,2WJZ8@28221|Deltaproteobacteria,2MI00@213118|Desulfobacterales	28221|Deltaproteobacteria	NT	PFAM CheR methyltransferase, SAM binding domain	-	-	2.1.1.80	ko:K00575	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheR,CheR_N
k141_1676_2	1304885.AUEY01000001_gene3266	1.72e-172	506.0	COG0745@1|root,COG1413@1|root,COG0745@2|Bacteria,COG1413@2|Bacteria,1R5AP@1224|Proteobacteria,42P8K@68525|delta/epsilon subdivisions,2WKU6@28221|Deltaproteobacteria,2MIX2@213118|Desulfobacterales	28221|Deltaproteobacteria	CKT	HEAT repeats	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,Response_reg
k141_3315_1	55601.VANGNB10_cI0088	7.06e-34	119.0	2E6DG@1|root,33113@2|Bacteria,1QJRJ@1224|Proteobacteria,1THSU@1236|Gammaproteobacteria,1XXF8@135623|Vibrionales	135623|Vibrionales	-	-	VP2964	-	-	-	-	-	-	-	-	-	-	-	DUF4145
k141_3315_2	870967.VIS19158_22582	1.24e-23	99.0	COG3274@1|root,COG3274@2|Bacteria,1MUJ6@1224|Proteobacteria,1S09B@1236|Gammaproteobacteria,1XT5S@135623|Vibrionales	135623|Vibrionales	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
k141_2706_1	1304885.AUEY01000035_gene2231	1.06e-71	227.0	2B7QJ@1|root,320WJ@2|Bacteria,1MZ2E@1224|Proteobacteria,42SBE@68525|delta/epsilon subdivisions,2WPBG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_2706_2	439235.Dalk_5206	9.67e-90	295.0	2A7N3@1|root,30WK3@2|Bacteria,1NERD@1224|Proteobacteria,42P7M@68525|delta/epsilon subdivisions,2WJTH@28221|Deltaproteobacteria,2MIHK@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_1016_1	1500893.JQNB01000001_gene821	2.9e-164	495.0	COG4953@1|root,COG4953@2|Bacteria,1MUA9@1224|Proteobacteria,1RMBV@1236|Gammaproteobacteria,1X4XC@135614|Xanthomonadales	135614|Xanthomonadales	M	penicillin-binding protein	-	-	2.4.1.129	ko:K05367	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	BiPBP_C,Transgly,Transpeptidase
k141_1016_2	351627.Csac_1674	2.89e-07	58.5	COG1373@1|root,COG1373@2|Bacteria,1TP7X@1239|Firmicutes,247ZX@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
k141_3007_1	1122963.AUHB01000001_gene430	1.22e-16	77.4	COG1028@1|root,COG1028@2|Bacteria,1PHK3@1224|Proteobacteria,2UE86@28211|Alphaproteobacteria	28211|Alphaproteobacteria	IQ	NAD dependent epimerase/dehydratase family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
k141_3007_2	1172562.HCN_1133	4.04e-34	139.0	COG0223@1|root,COG2348@1|root,COG0223@2|Bacteria,COG2348@2|Bacteria,1RG1R@1224|Proteobacteria,42WP5@68525|delta/epsilon subdivisions,2YQT7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_3007_3	1122963.AUHB01000001_gene432	3.44e-182	526.0	COG1020@1|root,COG1020@2|Bacteria,1QK4F@1224|Proteobacteria,2TRUN@28211|Alphaproteobacteria,36ZNV@31993|Methylocystaceae	28211|Alphaproteobacteria	Q	Condensation domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Acyl_transf_1,Condensation,KAsynt_C_assoc,KR,Ketoacyl-synt_C,PP-binding,PS-DH,Thioesterase,ketoacyl-synt
k141_2707_2	1499967.BAYZ01000093_gene4029	1.39e-79	249.0	COG1216@1|root,COG1216@2|Bacteria,2NP6P@2323|unclassified Bacteria	2|Bacteria	S	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
k141_2707_3	1121406.JAEX01000002_gene890	7.21e-128	374.0	COG2358@1|root,COG2358@2|Bacteria,1MXW1@1224|Proteobacteria,42MR6@68525|delta/epsilon subdivisions,2WITP@28221|Deltaproteobacteria,2MAK6@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	TIGRFAM TRAP transporter solute receptor, TAXI family	-	-	-	ko:K07080	-	-	-	-	ko00000	-	-	-	NMT1_3
k141_1295_1	439235.Dalk_1534	5.86e-277	768.0	COG0747@1|root,COG0747@2|Bacteria,1MUZH@1224|Proteobacteria,42N74@68525|delta/epsilon subdivisions,2WKUN@28221|Deltaproteobacteria,2MI16@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035,ko:K15584	ko02010,ko02024,map02010,map02024	M00239,M00440	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
k141_1295_2	1123355.JHYO01000001_gene3259	2.83e-22	94.4	COG0601@1|root,COG0601@2|Bacteria,1MU8Z@1224|Proteobacteria,2TQKK@28211|Alphaproteobacteria,36ZQD@31993|Methylocystaceae	28211|Alphaproteobacteria	EP	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
k141_645_1	1121396.KB892912_gene4152	2.46e-67	230.0	COG1201@1|root,COG1201@2|Bacteria,1MUSW@1224|Proteobacteria,43CXV@68525|delta/epsilon subdivisions,2X861@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	helicase superfamily c-terminal domain	-	-	-	ko:K06877	-	-	-	-	ko00000	-	-	-	DEAD,Helicase_C
k141_4988_2	1348635.BBJY01000006_gene337	1.79e-176	498.0	COG0523@1|root,COG0523@2|Bacteria,1MVZV@1224|Proteobacteria,1RPKP@1236|Gammaproteobacteria,1XSPY@135623|Vibrionales	135623|Vibrionales	S	GTPases (G3E family)	-	-	-	-	-	-	-	-	-	-	-	-	cobW
k141_4988_3	55601.VANGNB10_cII0272c	1.8e-263	731.0	COG0038@1|root,COG0038@2|Bacteria,1MV4K@1224|Proteobacteria,1RQJW@1236|Gammaproteobacteria,1XT8H@135623|Vibrionales	135623|Vibrionales	P	Probably acts as an electrical shunt for an outwardly- directed proton pump that is linked to amino acid decarboxylation, as part of the extreme acid resistance (XAR) response	clcA	-	-	ko:K03281	-	-	-	-	ko00000	2.A.49	-	-	Voltage_CLC
k141_4988_4	675817.VDA_000757	1.38e-41	162.0	COG2200@1|root,COG2200@2|Bacteria,1NJQD@1224|Proteobacteria,1RNEP@1236|Gammaproteobacteria,1Y37A@135623|Vibrionales	135623|Vibrionales	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	CSS-motif,EAL
k141_4988_5	1265505.ATUG01000003_gene683	7.24e-67	214.0	COG2221@1|root,COG2221@2|Bacteria,1QZ61@1224|Proteobacteria,43CGY@68525|delta/epsilon subdivisions,2X7S4@28221|Deltaproteobacteria,2MIQ8@213118|Desulfobacterales	28221|Deltaproteobacteria	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4
k141_646_2	644282.Deba_1314	2.23e-64	211.0	COG0500@1|root,COG0500@2|Bacteria,1QW86@1224|Proteobacteria,43CRZ@68525|delta/epsilon subdivisions,2WN4Z@28221|Deltaproteobacteria	28221|Deltaproteobacteria	Q	Methyltransferase type 12	-	-	-	-	-	-	-	-	-	-	-	-	Dimerisation2,Methyltransf_2
k141_3273_1	1190603.AJYD01000015_gene904	2.01e-73	221.0	2CH43@1|root,34326@2|Bacteria,1NY0H@1224|Proteobacteria,1SQP6@1236|Gammaproteobacteria,1XXFJ@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_4728_52	1304284.L21TH_1778	9.45e-51	177.0	COG5464@1|root,COG5464@2|Bacteria,1TPB1@1239|Firmicutes,24B0D@186801|Clostridia,36GBY@31979|Clostridiaceae	186801|Clostridia	S	PD-(D/E)XK nuclease family transposase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4351,PDDEXK_2
k141_4728_53	190304.FN1552	5.73e-64	211.0	2A9ZF@1|root,30Z7W@2|Bacteria	2|Bacteria	S	RloB-like protein	-	-	-	-	-	-	-	-	-	-	-	-	RloB
k141_4728_54	190304.FN1553	2.39e-177	511.0	COG1106@1|root,COG1106@2|Bacteria,379FD@32066|Fusobacteria	32066|Fusobacteria	S	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K06926	-	-	-	-	ko00000	-	-	-	AAA_21
k141_2362_1	1265505.ATUG01000002_gene2761	1.49e-99	320.0	COG0449@1|root,COG0449@2|Bacteria,1MW4K@1224|Proteobacteria,42KZ7@68525|delta/epsilon subdivisions,2WJP6@28221|Deltaproteobacteria,2MIWZ@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	iAF987.Gmet_1487	GATase_6,SIS
k141_2921_1	29581.BW37_03985	7.02e-23	102.0	COG2199@1|root,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,2VMMZ@28216|Betaproteobacteria,4743U@75682|Oxalobacteraceae	28216|Betaproteobacteria	T	diguanylate cyclase	pleD	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Response_reg
k141_5262_1	1121396.KB892990_gene4512	3.9e-81	249.0	COG5266@1|root,COG5266@2|Bacteria,1NPUY@1224|Proteobacteria,42S45@68525|delta/epsilon subdivisions,2WNJ3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Domain of unknown function (DUF4198)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4198
k141_652_1	1307437.J139_02905	4.22e-107	317.0	COG3384@1|root,COG3384@2|Bacteria,1MXJZ@1224|Proteobacteria,1RR5P@1236|Gammaproteobacteria,2PZZI@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	S	Catalytic LigB subunit of aromatic ring-opening dioxygenase	-	-	-	ko:K15777	ko00965,map00965	-	R08836	RC00387	ko00000,ko00001,ko01000	-	-	-	LigB
k141_652_2	1341679.P253_01888	1.58e-114	340.0	COG0697@1|root,COG0697@2|Bacteria,1N024@1224|Proteobacteria,1RSNH@1236|Gammaproteobacteria,3NJJ7@468|Moraxellaceae	1236|Gammaproteobacteria	EG	EamA-like transporter family	yedA	-	-	-	-	-	-	-	-	-	-	-	EamA
k141_652_3	360910.BAV0883	1.03e-53	176.0	COG1396@1|root,COG1396@2|Bacteria,1QUCP@1224|Proteobacteria	1224|Proteobacteria	K	TRANSCRIPTIONal	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,HTH_3
k141_652_4	1051646.VITU9109_01987	8.16e-62	192.0	COG3791@1|root,COG3791@2|Bacteria,1N031@1224|Proteobacteria,1S8W1@1236|Gammaproteobacteria,1XYPG@135623|Vibrionales	135623|Vibrionales	S	Glutathione-dependent formaldehyde-activating enzyme	-	-	-	-	-	-	-	-	-	-	-	-	GFA
k141_652_5	945550.VISI1226_12046	2.08e-100	295.0	COG2184@1|root,COG2184@2|Bacteria,1R72A@1224|Proteobacteria,1RYM7@1236|Gammaproteobacteria,1XX81@135623|Vibrionales	135623|Vibrionales	D	Fic/DOC family	-	-	-	-	-	-	-	-	-	-	-	-	Fic
k141_652_7	1537917.JU82_06065	2.23e-12	63.5	COG0526@1|root,COG0526@2|Bacteria,1N728@1224|Proteobacteria,42V0C@68525|delta/epsilon subdivisions,2YQBD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	CO	Redox-active disulfide protein	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_3
k141_652_8	357804.Ping_1828	7.58e-157	447.0	COG0701@1|root,COG0701@2|Bacteria,1MUN8@1224|Proteobacteria,1RR9N@1236|Gammaproteobacteria,2QJ4Z@267894|Psychromonadaceae	1236|Gammaproteobacteria	S	Predicted permease	-	-	-	ko:K07089	-	-	-	-	ko00000	-	-	-	ArsP_1
k141_923_1	1121405.dsmv_2551	7.88e-160	488.0	COG2844@1|root,COG2844@2|Bacteria,1MV54@1224|Proteobacteria,42MN5@68525|delta/epsilon subdivisions,2WINN@28221|Deltaproteobacteria,2MI1W@213118|Desulfobacterales	28221|Deltaproteobacteria	O	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen	glnD	-	2.7.7.59	ko:K00990	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	-	-	-	ACT,DUF294,GlnD_UR_UTase,GlnE,HD,NTP_transf_2
k141_4325_1	675817.VDA_000219	0.0	1449.0	COG0507@1|root,COG1112@1|root,COG1502@1|root,COG0507@2|Bacteria,COG1112@2|Bacteria,COG1502@2|Bacteria,1N8SW@1224|Proteobacteria,1SN1Z@1236|Gammaproteobacteria,1XXPT@135623|Vibrionales	135623|Vibrionales	L	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_11,AAA_12,PLDc_2,Toprim
k141_4325_4	672.VV93_v1c07380	5.17e-91	268.0	COG1396@1|root,COG1396@2|Bacteria,1N9SB@1224|Proteobacteria,1SDEF@1236|Gammaproteobacteria,1XXX7@135623|Vibrionales	135623|Vibrionales	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
k141_4325_5	672.VV93_v1c07390	0.0	895.0	COG3550@1|root,COG3550@2|Bacteria,1MW9U@1224|Proteobacteria,1RU92@1236|Gammaproteobacteria,1XWSF@135623|Vibrionales	135623|Vibrionales	S	HipA-like C-terminal domain	-	-	2.7.11.1	ko:K07154	-	-	-	-	ko00000,ko01000,ko01001,ko02048	-	-	-	HipA_C
k141_4325_6	1201293.AKXQ01000006_gene240	1.56e-164	466.0	COG0583@1|root,COG0583@2|Bacteria,1MW16@1224|Proteobacteria,1RS6U@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
k141_4020_1	1121918.ARWE01000001_gene197	4.38e-168	484.0	COG2303@1|root,COG2303@2|Bacteria,1MV19@1224|Proteobacteria,42N4C@68525|delta/epsilon subdivisions,2WJIH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate	-	-	1.1.99.1	ko:K00108	ko00260,ko01100,map00260,map01100	M00555	R01025	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	GMC_oxred_C,GMC_oxred_N
k141_4020_2	1307759.JOMJ01000004_gene2460	7.2e-80	248.0	COG2186@1|root,COG2186@2|Bacteria,1QCHK@1224|Proteobacteria,42QUK@68525|delta/epsilon subdivisions,2WMVZ@28221|Deltaproteobacteria,2M9TN@213115|Desulfovibrionales	28221|Deltaproteobacteria	K	SMART regulatory protein GntR HTH	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
k141_924_1	1121396.KB893128_gene4413	5.97e-06	47.4	COG4261@1|root,COG4261@2|Bacteria,1MVXJ@1224|Proteobacteria,42PI2@68525|delta/epsilon subdivisions,2WMFI@28221|Deltaproteobacteria,2MKJC@213118|Desulfobacterales	28221|Deltaproteobacteria	S	lipid A biosynthesis acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Lip_A_acyltrans
k141_924_2	1121396.KB893128_gene4412	1.21e-82	249.0	COG1216@1|root,COG1216@2|Bacteria,1QVEM@1224|Proteobacteria,42TG8@68525|delta/epsilon subdivisions,2WQC2@28221|Deltaproteobacteria,2MPYZ@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
k141_4326_1	158190.SpiGrapes_0184	2.49e-44	159.0	COG1129@1|root,COG1129@2|Bacteria,2J5C4@203691|Spirochaetes	203691|Spirochaetes	P	ABC-type sugar transport system, ATPase component	-	-	3.6.3.17	ko:K02056	-	M00221	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.2	-	-	ABC_tran
k141_2922_2	675806.VII_000099	4.95e-40	134.0	COG3414@1|root,COG3414@2|Bacteria,1RHFW@1224|Proteobacteria,1S6Y5@1236|Gammaproteobacteria,1Y2DZ@135623|Vibrionales	135623|Vibrionales	G	PTS system, Lactose/Cellobiose specific IIB subunit	-	-	2.7.1.194	ko:K02822	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	M00283,M00550	R07671	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.7.1	-	-	PTS_IIB
k141_2922_3	1006004.GBAG_4153	2.83e-77	242.0	COG3037@1|root,COG3037@2|Bacteria,1MXCA@1224|Proteobacteria,1RQTD@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	protein conserved in bacteria	ulaA	-	2.7.1.194	ko:K02822,ko:K03475	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	M00283,M00550	R07671	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.7.1	-	-	EIIC-GAT
k141_4729_1	382245.ASA_2935	1.85e-42	148.0	COG2801@1|root,COG2963@1|root,COG2801@2|Bacteria,COG2963@2|Bacteria,1MVXQ@1224|Proteobacteria,1RPEW@1236|Gammaproteobacteria,1Y6KM@135624|Aeromonadales	135624|Aeromonadales	L	HTH-like domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_21,HTH_Tnp_1,rve
k141_654_1	338966.Ppro_0373	8.61e-83	263.0	COG3497@1|root,COG3497@2|Bacteria,1MX89@1224|Proteobacteria,42QD3@68525|delta/epsilon subdivisions,2WKMQ@28221|Deltaproteobacteria,43T9S@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Phage tail sheath C-terminal domain	-	-	-	ko:K06907	-	-	-	-	ko00000	-	-	-	Phage_sheath_1,Phage_sheath_1C
k141_1316_2	997346.HMPREF9374_2762	3.59e-31	114.0	2DNGN@1|root,32UIX@2|Bacteria,1VDJP@1239|Firmicutes,4HN33@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_1316_3	672.VV93_v1c43960	5.28e-27	115.0	COG3209@1|root,COG3209@2|Bacteria,1PDT2@1224|Proteobacteria,1TEF8@1236|Gammaproteobacteria,1XZDG@135623|Vibrionales	135623|Vibrionales	M	COG3209 Rhs family protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_1316_8	672.VV93_v1c43960	2.94e-26	112.0	COG3209@1|root,COG3209@2|Bacteria,1PDT2@1224|Proteobacteria,1TEF8@1236|Gammaproteobacteria,1XZDG@135623|Vibrionales	135623|Vibrionales	M	COG3209 Rhs family protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_926_1	243277.VC_A0724	1.36e-10	65.5	COG4148@1|root,COG4148@2|Bacteria,1MU8K@1224|Proteobacteria,1RQCV@1236|Gammaproteobacteria,1XT5C@135623|Vibrionales	135623|Vibrionales	P	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system	modC	GO:0003674,GO:0003824,GO:0005215,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015098,GO:0015103,GO:0015318,GO:0015399,GO:0015405,GO:0015412,GO:0015689,GO:0015698,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0034220,GO:0042623,GO:0042626,GO:0043225,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0098656,GO:0099133	3.6.3.29	ko:K02017	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.8	-	-	ABC_tran,TOBE
k141_926_2	1121403.AUCV01000007_gene1207	9.76e-09	56.2	COG4149@1|root,COG4149@2|Bacteria,1MUXR@1224|Proteobacteria,42S4V@68525|delta/epsilon subdivisions,2WVGU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02018	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	-	BPD_transp_1
k141_2365_1	1304885.AUEY01000005_gene820	3.48e-150	429.0	COG2048@1|root,COG2048@2|Bacteria,1N37J@1224|Proteobacteria,42P51@68525|delta/epsilon subdivisions,2WK1J@28221|Deltaproteobacteria,2MKTG@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Cysteine-rich domain	hdrB	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03389	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	CCG
k141_2605_2	1304885.AUEY01000016_gene3034	2.4e-109	331.0	28K1Z@1|root,2Z9RF@2|Bacteria,1P9AU@1224|Proteobacteria,42P7A@68525|delta/epsilon subdivisions,2WKG1@28221|Deltaproteobacteria,2MI0M@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_2605_3	1304885.AUEY01000016_gene3035	5.48e-120	365.0	COG1090@1|root,COG4276@1|root,COG1090@2|Bacteria,COG4276@2|Bacteria,1MUB4@1224|Proteobacteria,42PQ2@68525|delta/epsilon subdivisions,2WK6V@28221|Deltaproteobacteria,2MI2V@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF1731)	-	-	-	ko:K07071	-	-	-	-	ko00000	-	-	-	DUF1731,Epimerase,Polyketide_cyc
k141_2605_4	439235.Dalk_2650	1.23e-135	394.0	COG1045@1|root,COG1045@2|Bacteria,1MVFX@1224|Proteobacteria,42MND@68525|delta/epsilon subdivisions,2WJC3@28221|Deltaproteobacteria,2MIG5@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Bacterial transferase hexapeptide (six repeats)	cysE	-	2.3.1.30	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	M00021	R00586	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,SATase_N
k141_2605_5	96561.Dole_0327	4.3e-108	323.0	COG2404@1|root,COG2404@2|Bacteria,1QW0R@1224|Proteobacteria,43BQN@68525|delta/epsilon subdivisions,2X71Q@28221|Deltaproteobacteria,2MHUX@213118|Desulfobacterales	28221|Deltaproteobacteria	S	COG0618 Exopolyphosphatase-related proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_1317_1	177437.HRM2_23330	1.3e-67	228.0	COG0322@1|root,COG0322@2|Bacteria,1MV38@1224|Proteobacteria,42MB1@68525|delta/epsilon subdivisions,2WJ76@28221|Deltaproteobacteria,2MIHC@213118|Desulfobacterales	28221|Deltaproteobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:1902494,GO:1905347,GO:1905348,GO:1990391	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N
k141_2366_1	998674.ATTE01000001_gene714	9.31e-11	61.2	COG1343@1|root,COG1343@2|Bacteria,1NKK5@1224|Proteobacteria,1SH4M@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette	cas2	-	-	ko:K09951	-	-	-	-	ko00000,ko02048	-	-	-	CRISPR_Cas2
k141_2366_2	1121396.KB893074_gene3004	1.54e-08	55.8	COG5551@1|root,COG5551@2|Bacteria	2|Bacteria	S	defense response to virus	-	-	-	-	-	-	-	-	-	-	-	-	CRISPR_Cas6
k141_5264_1	1379281.AVAG01000093_gene1358	2.52e-219	624.0	COG1032@1|root,COG1032@2|Bacteria,1MUG3@1224|Proteobacteria,42N0P@68525|delta/epsilon subdivisions,2WJCQ@28221|Deltaproteobacteria,2M7X3@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	DUF3362,Radical_SAM,Radical_SAM_N
k141_2367_1	1121396.KB893061_gene2688	3.02e-71	229.0	COG1236@1|root,COG1236@2|Bacteria,1MUDD@1224|Proteobacteria,42N91@68525|delta/epsilon subdivisions,2WIMM@28221|Deltaproteobacteria,2MIKE@213118|Desulfobacterales	28221|Deltaproteobacteria	J	RNA-metabolising metallo-beta-lactamase	-	-	-	ko:K07576	-	-	-	-	ko00000	-	-	-	Beta-Casp,Lactamase_B,Lactamase_B_6,RMMBL
k141_5265_1	202956.BBNL01000024_gene839	1.42e-14	77.0	COG2951@1|root,COG2951@2|Bacteria,1MUZ3@1224|Proteobacteria,1RMQ6@1236|Gammaproteobacteria,3NKMR@468|Moraxellaceae	1236|Gammaproteobacteria	M	Transglycosylase SLT domain	mltB	GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005509,GO:0005575,GO:0005623,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0008150,GO:0008152,GO:0008932,GO:0008933,GO:0009056,GO:0009057,GO:0009253,GO:0009279,GO:0016020,GO:0016740,GO:0016757,GO:0019867,GO:0030203,GO:0030288,GO:0030312,GO:0030313,GO:0031402,GO:0031420,GO:0031975,GO:0042597,GO:0043167,GO:0043169,GO:0043170,GO:0044462,GO:0044464,GO:0046872,GO:0061783,GO:0071704,GO:0071944,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575	-	ko:K08305	-	-	-	-	ko00000,ko01000,ko01011	-	GH103	iECABU_c1320.ECABU_c29710,iNRG857_1313.NRG857_13215	SLT_2
k141_5265_2	1304885.AUEY01000049_gene1224	8.34e-19	79.0	2EMW1@1|root,33FI9@2|Bacteria,1NKQ9@1224|Proteobacteria,42X8U@68525|delta/epsilon subdivisions,2WT7Y@28221|Deltaproteobacteria,2MM6T@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Phospholipase_D-nuclease N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	PLDc_N
k141_2606_1	1133849.O3I_020935	4.88e-08	56.2	COG0346@1|root,COG0346@2|Bacteria,2IFKS@201174|Actinobacteria,4G0G1@85025|Nocardiaceae	201174|Actinobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase,Glyoxalase_4
k141_2606_2	28229.ND2E_2960	9.94e-39	143.0	COG0491@1|root,COG0491@2|Bacteria,1Q667@1224|Proteobacteria,1RSGC@1236|Gammaproteobacteria,2Q7J1@267889|Colwelliaceae	1236|Gammaproteobacteria	S	Metallo-beta-lactamase superfamily	VVA1313	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
k141_4730_1	1517681.HW45_03125	0.0	1424.0	COG0610@1|root,COG0610@2|Bacteria,1MU96@1224|Proteobacteria,1RP2Q@1236|Gammaproteobacteria,1XTCP@135623|Vibrionales	135623|Vibrionales	L	Subunit R is required for both nuclease and ATPase activities, but not for modification	-	-	3.1.21.3	ko:K01153	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	DUF3387,HSDR_N,ResIII
k141_5268_1	338966.Ppro_0741	1.46e-16	85.1	COG1032@1|root,COG1032@2|Bacteria,1Q5NG@1224|Proteobacteria,42V17@68525|delta/epsilon subdivisions,2WRD3@28221|Deltaproteobacteria,43U6Q@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	B12 binding domain	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
k141_2022_1	656519.Halsa_0741	2.24e-13	65.9	COG1943@1|root,COG1943@2|Bacteria,1V3YY@1239|Firmicutes,24IB0@186801|Clostridia,3WBUK@53433|Halanaerobiales	186801|Clostridia	L	PFAM transposase IS200-family protein	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
k141_2022_2	350688.Clos_2869	7e-81	251.0	COG1475@1|root,COG1475@2|Bacteria,1TP0I@1239|Firmicutes,2488X@186801|Clostridia,36DCH@31979|Clostridiaceae	186801|Clostridia	K	Belongs to the ParB family	noc	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
k141_2022_3	293826.Amet_4795	4.63e-89	270.0	COG0357@1|root,COG0357@2|Bacteria,1TPBT@1239|Firmicutes,247WM@186801|Clostridia,36EMZ@31979|Clostridiaceae	186801|Clostridia	J	Specifically methylates the N7 position of a guanine in 16S rRNA	rsmG	-	2.1.1.170	ko:K03501	-	-	-	-	ko00000,ko01000,ko03009,ko03036	-	-	-	GidB
k141_2022_4	1511.CLOST_2581	1.5e-305	850.0	COG0445@1|root,COG0445@2|Bacteria,1TQ4B@1239|Firmicutes,247U2@186801|Clostridia,25QGE@186804|Peptostreptococcaceae	186801|Clostridia	D	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34	gidA	-	-	ko:K03495	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko03016,ko03036	-	-	-	GIDA,GIDA_assoc
k141_2022_5	272563.CD630_36760	1.46e-198	565.0	COG0486@1|root,COG0486@2|Bacteria,1TPJF@1239|Firmicutes,248A9@186801|Clostridia,25QGZ@186804|Peptostreptococcaceae	186801|Clostridia	J	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34	mnmE	-	-	ko:K03650	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko01000,ko03016	-	-	-	MMR_HSR1,MnmE_helical,TrmE_N
k141_2022_6	1216932.CM240_2691	5.31e-58	188.0	COG1847@1|root,COG1847@2|Bacteria,1V3IN@1239|Firmicutes,249EA@186801|Clostridia,36F11@31979|Clostridiaceae	186801|Clostridia	S	R3H domain protein	jag	-	-	ko:K06346	-	-	-	-	ko00000	-	-	-	Jag_N,KH_4,R3H
k141_2022_7	1286171.EAL2_c22250	5.43e-79	243.0	COG0706@1|root,COG0706@2|Bacteria,1TQ0J@1239|Firmicutes,247V9@186801|Clostridia,25VNJ@186806|Eubacteriaceae	186801|Clostridia	U	Membrane protein insertase, YidC Oxa1 family	oxaA	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP
k141_2022_8	1035196.HMPREF9998_00137	2.33e-31	111.0	COG0759@1|root,COG0759@2|Bacteria,1VEIG@1239|Firmicutes,24QN4@186801|Clostridia	186801|Clostridia	S	Could be involved in insertion of integral membrane proteins into the membrane	yidD	-	-	ko:K08998	-	-	-	-	ko00000	-	-	-	Haemolytic
k141_2022_9	1280698.AUJS01000048_gene424	2.98e-32	116.0	COG0594@1|root,COG0594@2|Bacteria,1VA78@1239|Firmicutes,24QK5@186801|Clostridia,27VP3@189330|Dorea	186801|Clostridia	J	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme	rnpA	-	3.1.26.5	ko:K03536	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Ribonuclease_P
k141_2022_11	1286171.EAL2_c00010	1.01e-212	600.0	COG0593@1|root,COG0593@2|Bacteria,1TPV7@1239|Firmicutes,2490S@186801|Clostridia,25UYE@186806|Eubacteriaceae	186801|Clostridia	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	-	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
k141_2022_12	1121324.CLIT_4c02210	3.93e-162	465.0	COG0592@1|root,COG0592@2|Bacteria,1TQ7J@1239|Firmicutes,248EG@186801|Clostridia,25QH8@186804|Peptostreptococcaceae	186801|Clostridia	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	dnaN	-	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
k141_2022_13	1226322.HMPREF1545_04108	2.48e-15	70.5	COG2501@1|root,COG2501@2|Bacteria,1TU9W@1239|Firmicutes,25NDU@186801|Clostridia,2N7QR@216572|Oscillospiraceae	186801|Clostridia	S	S4 domain	-	-	-	ko:K14761	-	-	-	-	ko00000,ko03009	-	-	-	S4_2
k141_2022_14	1391646.AVSU01000021_gene3244	6.56e-139	407.0	COG1195@1|root,COG1195@2|Bacteria,1TP9U@1239|Firmicutes,247KY@186801|Clostridia,25R56@186804|Peptostreptococcaceae	186801|Clostridia	L	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP	recF	-	-	ko:K03629	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	SMC_N
k141_2022_16	1286171.EAL2_c00060	0.0	960.0	COG0187@1|root,COG0187@2|Bacteria,1TQ0R@1239|Firmicutes,248AV@186801|Clostridia,25VFV@186806|Eubacteriaceae	186801|Clostridia	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
k141_2022_17	1121324.CLIT_4c02260	0.0	1036.0	COG0188@1|root,COG0188@2|Bacteria,1TP2Z@1239|Firmicutes,2482G@186801|Clostridia,25R3D@186804|Peptostreptococcaceae	186801|Clostridia	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
k141_3504_1	384765.SIAM614_18284	2.37e-77	260.0	COG2199@1|root,COG4191@1|root,COG3706@2|Bacteria,COG4191@2|Bacteria,1QUXS@1224|Proteobacteria,2TYAE@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS_3,PAS_9
k141_1767_1	526222.Desal_3256	6.62e-33	120.0	COG0518@1|root,COG0518@2|Bacteria	2|Bacteria	F	GMP synthase (glutamine-hydrolyzing) activity	-	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase
k141_1767_2	439235.Dalk_4875	2.98e-43	147.0	COG1794@1|root,COG1794@2|Bacteria,1MV03@1224|Proteobacteria,42QQX@68525|delta/epsilon subdivisions,2WWFF@28221|Deltaproteobacteria,2MPFI@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Belongs to the aspartate glutamate racemases family	-	-	5.1.1.13	ko:K01779	ko00250,ko01054,map00250,map01054	-	R00491	RC00302	ko00000,ko00001,ko01000	-	-	-	Asp_Glu_race
k141_1768_1	177437.HRM2_13510	4.29e-23	96.7	COG0012@1|root,COG0012@2|Bacteria,1MVM4@1224|Proteobacteria,42MNJ@68525|delta/epsilon subdivisions,2WIZZ@28221|Deltaproteobacteria,2MIHN@213118|Desulfobacterales	28221|Deltaproteobacteria	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
k141_1057_1	1219065.VPR01S_33_00070	3.61e-231	644.0	COG0373@1|root,COG0373@2|Bacteria,1MU41@1224|Proteobacteria,1RNQ8@1236|Gammaproteobacteria,1XTUS@135623|Vibrionales	135623|Vibrionales	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	GO:0003674,GO:0003824,GO:0006725,GO:0006778,GO:0006779,GO:0006807,GO:0008150,GO:0008152,GO:0008883,GO:0009058,GO:0009987,GO:0016491,GO:0016620,GO:0016903,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0044237,GO:0044249,GO:0044271,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0140098,GO:0140101,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,GlutR_dimer,Shikimate_DH
k141_1057_2	675816.VIA_003625	4.41e-53	176.0	COG3017@1|root,COG3017@2|Bacteria,1N02T@1224|Proteobacteria,1S91E@1236|Gammaproteobacteria,1XX2S@135623|Vibrionales	135623|Vibrionales	M	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein	lolB	GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944	-	ko:K02494	-	-	-	-	ko00000	-	-	-	LolB
k141_1057_3	945550.VISI1226_21659	1.11e-134	387.0	COG1947@1|root,COG1947@2|Bacteria,1MVU3@1224|Proteobacteria,1RP23@1236|Gammaproteobacteria,1XUCF@135623|Vibrionales	135623|Vibrionales	F	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol	ispE	GO:0003674,GO:0003824,GO:0006629,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0050515,GO:0071704,GO:1901576	2.7.1.148	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05634	RC00002,RC01439	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
k141_439_1	525897.Dbac_1784	2.54e-194	554.0	COG0662@1|root,COG0836@1|root,COG0662@2|Bacteria,COG0836@2|Bacteria,1MV39@1224|Proteobacteria,42MDP@68525|delta/epsilon subdivisions,2WJEN@28221|Deltaproteobacteria,2M8IG@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	TIGRFAM Mannose-1-phosphate guanylyltransferase mannose-6-phosphate isomerase	-	-	2.7.7.13,5.3.1.8	ko:K00971,ko:K16011	ko00051,ko00520,ko01100,ko01110,ko01130,ko02025,map00051,map00520,map01100,map01110,map01130,map02025	M00114,M00361,M00362	R00885,R01819	RC00002,RC00376	ko00000,ko00001,ko00002,ko01000	-	-	-	MannoseP_isomer,NTP_transferase
k141_1769_2	1219080.VEZ01S_10_00320	1.46e-12	65.5	COG0139@1|root,COG0140@1|root,COG0139@2|Bacteria,COG0140@2|Bacteria,1MW67@1224|Proteobacteria,1RMV4@1236|Gammaproteobacteria,1XT5G@135623|Vibrionales	135623|Vibrionales	E	Histidine biosynthesis bifunctional protein HisIE	hisI	GO:0000105,GO:0003674,GO:0003824,GO:0004635,GO:0004636,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016462,GO:0016787,GO:0016810,GO:0016814,GO:0016817,GO:0016818,GO:0018130,GO:0019238,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	3.5.4.19,3.6.1.31	ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04035,R04037	RC00002,RC01055	ko00000,ko00001,ko00002,ko01000	-	-	-	PRA-CH,PRA-PH
k141_440_1	1054217.TALC_00287	2.2e-20	90.9	COG1145@1|root,arCOG00296@2157|Archaea,2XUE5@28890|Euryarchaeota	28890|Euryarchaeota	C	PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_21,Fer4_9
k141_3788_1	526222.Desal_3801	5.1e-27	108.0	COG3437@1|root,COG3437@2|Bacteria,1MUB8@1224|Proteobacteria,42QAG@68525|delta/epsilon subdivisions,2X5DT@28221|Deltaproteobacteria,2MGPX@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	response regulator, receiver	-	-	-	ko:K07814	-	-	-	-	ko00000,ko02022	-	-	-	HD,HD_5,Response_reg
k141_3788_4	293826.Amet_1672	1.4e-11	64.7	COG1714@1|root,COG1714@2|Bacteria,1VIRT@1239|Firmicutes,24TSH@186801|Clostridia,36N4N@31979|Clostridiaceae	186801|Clostridia	S	RDD family	-	-	-	-	-	-	-	-	-	-	-	-	RDD
k141_3788_5	545693.BMQ_0360	8.4e-310	852.0	COG0488@1|root,COG0488@2|Bacteria,1TPAX@1239|Firmicutes,4HC58@91061|Bacilli,1ZB1Y@1386|Bacillus	91061|Bacilli	S	COG0488 ATPase components of ABC transporters with duplicated ATPase domains	yheS_1	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,ABC_tran_Xtn
k141_3788_8	431943.CKL_0435	3.95e-141	421.0	COG0513@1|root,COG0513@2|Bacteria,1TPAP@1239|Firmicutes,247IT@186801|Clostridia,36EGF@31979|Clostridiaceae	186801|Clostridia	L	DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes	dbpA	-	3.6.4.13	ko:K05592	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	DEAD,DbpA,Helicase_C
k141_3788_10	938288.HG326226_gene565	2.42e-71	219.0	COG2077@1|root,COG2077@2|Bacteria,1V474@1239|Firmicutes,24HUY@186801|Clostridia	186801|Clostridia	O	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides	tpx	-	1.11.1.15	ko:K11065	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA,Redoxin
k141_3788_14	457570.Nther_0617	1.84e-74	235.0	COG0705@1|root,COG0705@2|Bacteria,1TSBP@1239|Firmicutes,249D8@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
k141_3788_15	1499683.CCFF01000017_gene2245	1.88e-162	465.0	COG0505@1|root,COG0505@2|Bacteria,1TQ8N@1239|Firmicutes,247Q8@186801|Clostridia,36DTQ@31979|Clostridiaceae	186801|Clostridia	F	Belongs to the CarA family	carA	-	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_sm_chain,GATase
k141_3788_16	318464.IO99_10575	0.0	1426.0	COG0458@1|root,COG0458@2|Bacteria,1TPID@1239|Firmicutes,2498I@186801|Clostridia,36DIP@31979|Clostridiaceae	186801|Clostridia	F	Carbamoyl-phosphate synthetase ammonia chain	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
k141_3788_21	1319815.HMPREF0202_02853	2.15e-112	335.0	COG0675@1|root,COG0675@2|Bacteria,379SD@32066|Fusobacteria	32066|Fusobacteria	L	transposase IS891 IS1136 IS1341 family	-	-	-	ko:K07496	-	-	-	-	ko00000	-	-	-	HTH_OrfB_IS605,OrfB_IS605,OrfB_Zn_ribbon
k141_1424_1	1121324.CLIT_23c02690	9.41e-100	335.0	COG0265@1|root,COG0265@2|Bacteria,1UHT3@1239|Firmicutes,25EW9@186801|Clostridia	186801|Clostridia	O	Putative component of 'biosynthetic module'	-	-	-	-	-	-	-	-	-	-	-	-	YceG_bac
k141_1424_2	1121324.CLIT_23c02680	3.02e-127	376.0	COG3853@1|root,COG3853@2|Bacteria,1TQVX@1239|Firmicutes,24A2H@186801|Clostridia,25QIY@186804|Peptostreptococcaceae	186801|Clostridia	P	Toxic anion resistance protein (TelA)	-	-	-	-	-	-	-	-	-	-	-	-	TelA
k141_1424_3	632245.CLP_4219	1.69e-93	291.0	COG2206@1|root,COG2206@2|Bacteria,1TQIM@1239|Firmicutes,248S5@186801|Clostridia,36FJB@31979|Clostridiaceae	186801|Clostridia	T	SMART Metal-dependent phosphohydrolase, HD region	rpfG1	-	-	-	-	-	-	-	-	-	-	-	HD,HD_5
k141_1424_4	1121324.CLIT_23c01930	5.03e-307	856.0	COG3855@1|root,COG3855@2|Bacteria,1TPFU@1239|Firmicutes,248ZC@186801|Clostridia,25QCE@186804|Peptostreptococcaceae	186801|Clostridia	G	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 3	fbp	-	3.1.3.11	ko:K04041	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00165,M00167	R00762,R04780	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FBPase_2
k141_1424_5	1392491.JIAE01000001_gene2425	3.5e-52	180.0	COG1597@1|root,COG1597@2|Bacteria,1TQAU@1239|Firmicutes,249SY@186801|Clostridia,3WHA2@541000|Ruminococcaceae	186801|Clostridia	I	lipid kinase, YegS Rv2252 BmrU family	dagK	-	2.7.1.107	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	-	R02240	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	DAGK_cat
k141_1424_8	1033737.CAEV01000077_gene692	3e-101	299.0	COG0274@1|root,COG0274@2|Bacteria,1TPAJ@1239|Firmicutes,249XB@186801|Clostridia,36DTB@31979|Clostridiaceae	186801|Clostridia	F	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate	deoC	-	4.1.2.4	ko:K01619	ko00030,map00030	-	R01066	RC00436,RC00437	ko00000,ko00001,ko01000	-	-	-	DeoC
k141_1424_9	1321778.HMPREF1982_04515	2.92e-77	246.0	COG1752@1|root,COG1752@2|Bacteria,1TRJW@1239|Firmicutes,248J0@186801|Clostridia	186801|Clostridia	S	esterase of the alpha-beta hydrolase superfamily	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
k141_1424_11	926692.AZYG01000059_gene163	3.68e-51	180.0	COG1263@1|root,COG2190@1|root,COG1263@2|Bacteria,COG2190@2|Bacteria,1TPJ8@1239|Firmicutes,24809@186801|Clostridia,3WBJZ@53433|Halanaerobiales	1239|Firmicutes	G	phosphotransferase system, EIIB	-	-	2.7.1.199	ko:K20116,ko:K20117,ko:K20118	ko00010,ko00520,ko02060,map00010,map00520,map02060	M00809	R02738	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.1.1.13,4.A.1.1.14,4.A.1.1.9	-	-	PTS_EIIA_1,PTS_EIIB,PTS_EIIC
k141_1424_12	1304284.L21TH_1863	4.16e-118	344.0	COG0363@1|root,COG0363@2|Bacteria,1TP10@1239|Firmicutes,248HK@186801|Clostridia,36E4F@31979|Clostridiaceae	186801|Clostridia	G	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion	nagB	-	3.5.99.6	ko:K02564	ko00520,ko01100,map00520,map01100	-	R00765	RC00163	ko00000,ko00001,ko01000	-	-	-	Glucosamine_iso
k141_1424_13	1304284.L21TH_1862	7.79e-146	425.0	COG1820@1|root,COG1820@2|Bacteria,1TPFK@1239|Firmicutes,2481N@186801|Clostridia,36FD4@31979|Clostridiaceae	186801|Clostridia	G	Belongs to the metallo-dependent hydrolases superfamily. NagA family	nagA	-	3.5.1.25	ko:K01443	ko00520,ko01130,map00520,map01130	-	R02059	RC00166,RC00300	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
k141_4828_2	55601.VANGNB10_cI0985	1.9e-193	565.0	COG0760@1|root,COG0760@2|Bacteria,1MWV0@1224|Proteobacteria,1RMT5@1236|Gammaproteobacteria,1XT2A@135623|Vibrionales	135623|Vibrionales	O	Peptidylprolyl isomerase	ppiD	-	5.2.1.8	ko:K03770	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase_2,Rotamase_3,SurA_N_3
k141_4828_3	243277.VC_1917	2.22e-25	98.2	COG1555@1|root,COG1555@2|Bacteria,1N6Q3@1224|Proteobacteria,1SC7U@1236|Gammaproteobacteria,1XYXQ@135623|Vibrionales	135623|Vibrionales	L	COG1555 DNA uptake protein and related DNA-binding proteins	-	-	-	ko:K02237	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	HHH_3
k141_4829_1	1122173.AXVL01000039_gene2422	4.05e-11	68.9	COG3500@1|root,COG3500@2|Bacteria,379HW@32066|Fusobacteria	32066|Fusobacteria	S	Late control gene D protein	-	-	-	ko:K06905	-	-	-	-	ko00000	-	-	-	Phage_GPD
k141_4495_1	1238450.VIBNISOn1_1370016	5.52e-120	359.0	COG1129@1|root,COG1129@2|Bacteria,1MU22@1224|Proteobacteria,1RMCH@1236|Gammaproteobacteria,1XTBT@135623|Vibrionales	135623|Vibrionales	P	Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system	-	-	3.6.3.17	ko:K10441	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	ABC_tran
k141_4495_2	1238450.VIBNISOn1_1370017	1.09e-119	352.0	COG1172@1|root,COG1172@2|Bacteria,1MX7D@1224|Proteobacteria,1RNTS@1236|Gammaproteobacteria,1XTC8@135623|Vibrionales	135623|Vibrionales	G	Belongs to the binding-protein-dependent transport system permease family	rbsC	-	-	ko:K10440	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	BPD_transp_2
k141_4122_2	55601.VANGNB10_cI1984	1.1e-238	659.0	COG0012@1|root,COG0012@2|Bacteria,1MVM4@1224|Proteobacteria,1RMBI@1236|Gammaproteobacteria,1XTPY@135623|Vibrionales	135623|Vibrionales	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
k141_4122_4	34506.g5900	2.39e-243	724.0	COG0012@1|root,COG0193@1|root,COG0462@1|root,KOG1448@2759|Eukaryota,KOG1491@2759|Eukaryota,KOG2255@2759|Eukaryota,39V55@33154|Opisthokonta,3BX8R@33208|Metazoa	33208|Metazoa	J	Peptidyl-tRNA hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	MMR_HSR1,Pept_tRNA_hydro
k141_4122_5	1219065.VPR01S_33_00080	1.03e-53	177.0	COG3017@1|root,COG3017@2|Bacteria,1N02T@1224|Proteobacteria,1S91E@1236|Gammaproteobacteria,1XX2S@135623|Vibrionales	135623|Vibrionales	M	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein	lolB	GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944	-	ko:K02494	-	-	-	-	ko00000	-	-	-	LolB
k141_4122_6	1219065.VPR01S_33_00070	4.42e-206	581.0	COG0373@1|root,COG0373@2|Bacteria,1MU41@1224|Proteobacteria,1RNQ8@1236|Gammaproteobacteria,1XTUS@135623|Vibrionales	135623|Vibrionales	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	GO:0003674,GO:0003824,GO:0006725,GO:0006778,GO:0006779,GO:0006807,GO:0008150,GO:0008152,GO:0008883,GO:0009058,GO:0009987,GO:0016491,GO:0016620,GO:0016903,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0044237,GO:0044249,GO:0044271,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0140098,GO:0140101,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,GlutR_dimer,Shikimate_DH
k141_4122_7	55601.VANGNB10_cI1978c	4.58e-219	609.0	COG0216@1|root,COG0216@2|Bacteria,1MV28@1224|Proteobacteria,1RM7Q@1236|Gammaproteobacteria,1XTF3@135623|Vibrionales	135623|Vibrionales	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
k141_4122_8	243277.VC_2178	2.82e-129	375.0	COG2890@1|root,COG2890@2|Bacteria,1MXCQ@1224|Proteobacteria,1RNGK@1236|Gammaproteobacteria,1XTR8@135623|Vibrionales	135623|Vibrionales	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif	prmC	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0032259,GO:0036009,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	Methyltransf_31
k141_4122_9	243277.VC_2176	2.16e-139	400.0	COG2912@1|root,COG2912@2|Bacteria,1MVJQ@1224|Proteobacteria,1RQ7V@1236|Gammaproteobacteria,1XSET@135623|Vibrionales	135623|Vibrionales	S	Transglutaminase-like superfamily	ychA	-	-	-	-	-	-	-	-	-	-	-	TPR_9,Transglut_core2
k141_4122_10	29495.EA26_04590	2.36e-186	520.0	COG2877@1|root,COG2877@2|Bacteria,1MV91@1224|Proteobacteria,1RMGQ@1236|Gammaproteobacteria,1XSUC@135623|Vibrionales	135623|Vibrionales	M	Belongs to the KdsA family	kdsA	GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0005996,GO:0006082,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008676,GO:0009058,GO:0009059,GO:0009103,GO:0009987,GO:0016051,GO:0016053,GO:0016740,GO:0016765,GO:0019294,GO:0019752,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044281,GO:0044283,GO:0046364,GO:0046394,GO:0046400,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509	2.5.1.55	ko:K01627	ko00540,ko01100,map00540,map01100	M00063	R03254	RC00435	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	DAHP_synth_1
k141_4122_11	223926.28805735	6.05e-77	233.0	COG2606@1|root,COG2606@2|Bacteria,1RGX5@1224|Proteobacteria,1S6S0@1236|Gammaproteobacteria,1XX0H@135623|Vibrionales	135623|Vibrionales	S	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily	ybaK	-	-	ko:K03976	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA_edit
k141_4122_12	400668.Mmwyl1_4298	2.99e-229	639.0	COG2233@1|root,COG2233@2|Bacteria,1MUN9@1224|Proteobacteria,1RRK5@1236|Gammaproteobacteria,1XIR6@135619|Oceanospirillales	135619|Oceanospirillales	F	Xanthine uracil	uraA	-	-	ko:K02824	-	-	-	-	ko00000,ko02000	2.A.40.1.1,2.A.40.1.2	-	-	Xan_ur_permease
k141_4122_13	1219065.VPR01S_03_03050	2.56e-87	278.0	COG3249@1|root,COG3249@2|Bacteria,1N0PD@1224|Proteobacteria,1S9C4@1236|Gammaproteobacteria,1XU1W@135623|Vibrionales	135623|Vibrionales	S	protein conserved in bacteria	VV2512	-	-	ko:K09938	-	-	-	-	ko00000	-	-	-	DUF2066
k141_4122_14	945550.VISI1226_21729	2.65e-45	149.0	COG1393@1|root,COG1393@2|Bacteria,1MZ4Z@1224|Proteobacteria,1S8XH@1236|Gammaproteobacteria,1XXT8@135623|Vibrionales	135623|Vibrionales	C	COG1393 Arsenate reductase and related proteins, glutaredoxin family	arsC	-	1.20.4.1	ko:K00537	-	-	-	-	ko00000,ko01000	-	-	-	ArsC
k141_4122_15	55601.VANGNB10_cI1966	9.81e-184	530.0	COG4783@1|root,COG4783@2|Bacteria,1MVFV@1224|Proteobacteria,1RP5S@1236|Gammaproteobacteria,1XUZK@135623|Vibrionales	135623|Vibrionales	S	Functions as both a chaperone and a metalloprotease. Maintains the integrity of the outer membrane by promoting either the assembly or the elimination of outer membrane proteins, depending on their folding state	yfgC	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48,TPR_19,TPR_8
k141_4122_16	675814.VIC_004780	2.99e-177	503.0	COG0628@1|root,COG0628@2|Bacteria,1MW0B@1224|Proteobacteria,1RPVP@1236|Gammaproteobacteria,1XV05@135623|Vibrionales	135623|Vibrionales	S	AI-2E family transporter	perM	-	-	ko:K03548	-	-	-	-	ko00000,ko02000	2.A.86.1	-	-	AI-2E_transport
k141_4122_17	675815.VOA_002505	1.67e-201	585.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,1XUI8@135623|Vibrionales	135623|Vibrionales	NT	methyl-accepting chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal,dCache_1
k141_4122_18	675816.VIA_003601	3.58e-84	251.0	COG1225@1|root,COG1225@2|Bacteria,1RD4R@1224|Proteobacteria,1RQ7F@1236|Gammaproteobacteria,1XSCX@135623|Vibrionales	135623|Vibrionales	O	COG1225 Peroxiredoxin	bcp	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
k141_4122_19	675813.VIB_000752	1.58e-161	457.0	COG0329@1|root,COG0329@2|Bacteria,1MUCM@1224|Proteobacteria,1RNH9@1236|Gammaproteobacteria,1XUPA@135623|Vibrionales	135623|Vibrionales	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA	GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008840,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
k141_4122_20	1348635.BBJY01000007_gene282	1.82e-99	304.0	COG3317@1|root,COG3317@2|Bacteria,1MUUK@1224|Proteobacteria,1RN2X@1236|Gammaproteobacteria,1XTAQ@135623|Vibrionales	135623|Vibrionales	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamC	-	-	ko:K07287	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	Lipoprotein_18
k141_4122_22	945550.VISI1226_02927	4.44e-93	279.0	COG1876@1|root,COG1876@2|Bacteria,1N2IC@1224|Proteobacteria,1S0DU@1236|Gammaproteobacteria,1XTV4@135623|Vibrionales	135623|Vibrionales	M	COG1876 D-alanyl-D-alanine carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	VanY
k141_4122_23	55601.VANGNB10_cI1957	1.31e-233	647.0	COG0624@1|root,COG0624@2|Bacteria,1MW6G@1224|Proteobacteria,1RMNQ@1236|Gammaproteobacteria,1XTY6@135623|Vibrionales	135623|Vibrionales	E	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls	dapE	GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009014,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016787,GO:0016810,GO:0016811,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	3.5.1.18	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R02734	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20
k141_4122_24	617140.AJZE01000047_gene3374	3.97e-53	169.0	COG1393@1|root,COG1393@2|Bacteria,1MZ6S@1224|Proteobacteria,1S8TR@1236|Gammaproteobacteria,1XXZI@135623|Vibrionales	135623|Vibrionales	P	Belongs to the ArsC family	yffB	-	-	-	-	-	-	-	-	-	-	-	ArsC
k141_4122_25	1219065.VPR01S_03_02890	7.45e-53	167.0	COG4519@1|root,COG4519@2|Bacteria,1N38K@1224|Proteobacteria,1SAIP@1236|Gammaproteobacteria,1XXSB@135623|Vibrionales	135623|Vibrionales	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	HTH_43
k141_4122_26	672.VV93_v1c21980	7.54e-23	92.8	2E37U@1|root,32Y7H@2|Bacteria,1N8JQ@1224|Proteobacteria,1SCAH@1236|Gammaproteobacteria,1XYDU@135623|Vibrionales	135623|Vibrionales	S	Protein of unknown function (DUF2956)	VC2147	-	-	-	-	-	-	-	-	-	-	-	DUF2956
k141_4122_27	243277.VC_2145	3.76e-153	437.0	COG2837@1|root,COG2837@2|Bacteria,1MWDD@1224|Proteobacteria,1RMZJ@1236|Gammaproteobacteria,1XU5E@135623|Vibrionales	135623|Vibrionales	P	iron-dependent peroxidase	-	-	-	ko:K07223	-	-	-	-	ko00000	-	-	-	Dyp_perox
k141_4122_28	1348635.BBJY01000007_gene272	4.74e-199	560.0	COG1344@1|root,COG1344@2|Bacteria,1MV1N@1224|Proteobacteria,1RN0Y@1236|Gammaproteobacteria,1XSDK@135623|Vibrionales	135623|Vibrionales	N	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella	flaB	GO:0005575,GO:0005576,GO:0005623,GO:0009288,GO:0042995,GO:0043226,GO:0043228,GO:0044464	-	ko:K02406	ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flagellin_C,Flagellin_IN,Flagellin_N
k141_4122_29	1219065.VPR01S_03_02820	9.81e-196	551.0	COG1344@1|root,COG1344@2|Bacteria,1MV1N@1224|Proteobacteria,1RN0Y@1236|Gammaproteobacteria,1XSDK@135623|Vibrionales	135623|Vibrionales	N	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella	flaB	GO:0005575,GO:0005576,GO:0005623,GO:0009288,GO:0042995,GO:0043226,GO:0043228,GO:0044464	-	ko:K02406	ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flagellin_C,Flagellin_IN,Flagellin_N
k141_4122_30	675815.VOA_002481	1.78e-40	140.0	COG1334@1|root,COG1334@2|Bacteria,1NH9T@1224|Proteobacteria,1SH7I@1236|Gammaproteobacteria,1XX73@135623|Vibrionales	135623|Vibrionales	N	flagellar protein FlaG	flaG	-	-	ko:K06603	-	-	-	-	ko00000,ko02035	-	-	-	FlaG
k141_4122_31	675815.VOA_002480	3.11e-266	753.0	COG1345@1|root,COG1345@2|Bacteria,1MUVP@1224|Proteobacteria,1RS2S@1236|Gammaproteobacteria,1XU55@135623|Vibrionales	135623|Vibrionales	N	morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end	fliD	GO:0001539,GO:0003674,GO:0005198,GO:0005575,GO:0005576,GO:0005623,GO:0006928,GO:0008150,GO:0009288,GO:0009420,GO:0009421,GO:0009424,GO:0009987,GO:0040011,GO:0042995,GO:0043226,GO:0043228,GO:0044422,GO:0044461,GO:0044463,GO:0044464,GO:0048870,GO:0051179,GO:0051674,GO:0071973,GO:0097588	-	ko:K02407	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flagellin_IN,FliD_C,FliD_N
k141_4122_32	675815.VOA_002479	9.49e-29	106.0	2AWMQ@1|root,31NIF@2|Bacteria,1QK94@1224|Proteobacteria,1TICJ@1236|Gammaproteobacteria,1XYVG@135623|Vibrionales	135623|Vibrionales	-	-	flaI	-	-	ko:K06604	-	-	-	-	ko00000	-	-	-	-
k141_4122_33	870967.VIS19158_09109	4.9e-84	249.0	COG1516@1|root,COG1516@2|Bacteria,1MZ3G@1224|Proteobacteria,1S8TQ@1236|Gammaproteobacteria,1XWX6@135623|Vibrionales	135623|Vibrionales	N	Flagellar protein FliS	fliS	GO:0003674,GO:0005198	-	ko:K02422	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliS
k141_4122_34	243277.VC_2137	1.7e-276	765.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1T1IW@1236|Gammaproteobacteria,1XT5N@135623|Vibrionales	135623|Vibrionales	T	COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains	flaK	-	-	ko:K10941	ko02020,ko02025,ko05111,map02020,map02025,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	FleQ,HTH_8,Sigma54_activat
k141_4122_35	1348635.BBJY01000007_gene265	8.49e-193	541.0	COG5000@1|root,COG5000@2|Bacteria,1QUG9@1224|Proteobacteria,1T1Y1@1236|Gammaproteobacteria,1XSAF@135623|Vibrionales	135623|Vibrionales	T	COG0642 Signal transduction histidine kinase	flrB	-	2.7.13.3	ko:K10942	ko02020,ko05111,map02020,map05111	M00515	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,PAS_8
k141_4122_40	223926.28807240	1.3e-94	286.0	COG1317@1|root,COG1317@2|Bacteria,1RB8Y@1224|Proteobacteria,1T18Q@1236|Gammaproteobacteria,1XTTU@135623|Vibrionales	135623|Vibrionales	N	COG1317 Flagellar biosynthesis type III secretory pathway protein	fliH	-	-	ko:K02411	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	FliH,Yae1_N
k141_4122_41	55601.VANGNB10_cI1936c	1.9e-281	773.0	COG1157@1|root,COG1157@2|Bacteria,1MUH6@1224|Proteobacteria,1RM9W@1236|Gammaproteobacteria,1XTKF@135623|Vibrionales	135623|Vibrionales	NU	COG1157 Flagellar biosynthesis type III secretory pathway ATPase	fliI	-	3.6.3.14	ko:K02412	ko02040,map02040	-	-	-	ko00000,ko00001,ko01000,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	ATP-synt_ab
k141_4122_42	1348635.BBJY01000007_gene258	6.17e-61	191.0	COG2882@1|root,COG2882@2|Bacteria,1NANM@1224|Proteobacteria,1SD9U@1236|Gammaproteobacteria,1XXD9@135623|Vibrionales	135623|Vibrionales	N	COG2882 Flagellar biosynthesis chaperone	fliJ	-	-	ko:K02413	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliJ
k141_4122_43	945550.VISI1226_11304	2.3e-39	160.0	COG3144@1|root,COG3144@2|Bacteria,1N7XT@1224|Proteobacteria,1SCA6@1236|Gammaproteobacteria,1XSXC@135623|Vibrionales	135623|Vibrionales	N	Flagellar hook-length control protein	fliK	-	-	ko:K02414	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_hook
k141_168_1	1348635.BBJY01000001_gene2384	7.07e-166	478.0	COG0535@1|root,COG0535@2|Bacteria,1MWDC@1224|Proteobacteria,1RRMW@1236|Gammaproteobacteria,1XZZN@135623|Vibrionales	135623|Vibrionales	C	Dinitrogenase iron-molybdenum cofactor	-	-	-	ko:K02585	-	-	-	-	ko00000	-	-	-	Nitro_FeMo-Co,Radical_SAM
k141_168_2	1348635.BBJY01000001_gene2383	7.39e-286	793.0	COG3604@1|root,COG3604@2|Bacteria,1QTT3@1224|Proteobacteria,1T1G7@1236|Gammaproteobacteria,1XW1P@135623|Vibrionales	135623|Vibrionales	KT	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	-	ko:K02584	ko02020,map02020	-	-	-	ko00000,ko00001,ko03000	-	-	-	GAF,GAF_2,HTH_8,Sigma54_activat
k141_168_3	1515746.HR45_08690	3.28e-229	645.0	COG4191@1|root,COG4191@2|Bacteria,1MXRR@1224|Proteobacteria,1RQ1E@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	nitrogen fixation negative regulator NifL	nifL	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,PAS,PAS_8,PAS_9
k141_5147_1	1125725.HMPREF1325_1360	6.92e-64	209.0	COG3681@1|root,COG3681@2|Bacteria,2J6AS@203691|Spirochaetes	203691|Spirochaetes	S	Belongs to the UPF0597 family	-	-	-	-	-	-	-	-	-	-	-	-	SDH_alpha
k141_5147_2	1125725.HMPREF1325_1359	1.99e-246	688.0	COG1757@1|root,COG1757@2|Bacteria,2JA9Q@203691|Spirochaetes	203691|Spirochaetes	C	Na+/H+ antiporter family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_antiporter
k141_5147_3	762983.HMPREF9444_01682	8.51e-24	94.4	COG0251@1|root,COG0251@2|Bacteria,1MZ3J@1224|Proteobacteria,1S5XS@1236|Gammaproteobacteria	1236|Gammaproteobacteria	J	Endoribonuclease	yhaR	-	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP
k141_169_1	1136163.M565_ctg5P1104	2.9e-40	152.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1R81Y@1224|Proteobacteria,1RYQ2@1236|Gammaproteobacteria,1XUTT@135623|Vibrionales	135623|Vibrionales	T	COG0642 Signal transduction histidine kinase	luxN	-	2.7.13.3	ko:K15850	ko02020,ko02024,map02020,map02024	-	-	-	ko00000,ko00001,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,Response_reg
k141_750_2	264462.Bd3688	7.2e-113	335.0	COG0583@1|root,COG0583@2|Bacteria,1MU2E@1224|Proteobacteria,42T5W@68525|delta/epsilon subdivisions,2MTTD@213481|Bdellovibrionales,2WPVR@28221|Deltaproteobacteria	213481|Bdellovibrionales	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
k141_2489_4	945550.VISI1226_05566	1.98e-127	369.0	arCOG03638@1|root,2Z8W3@2|Bacteria,1N2PH@1224|Proteobacteria,1RMI8@1236|Gammaproteobacteria,1XUA3@135623|Vibrionales	135623|Vibrionales	S	Protein of unknown function (DUF1538)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1538
k141_3577_1	1348635.BBJY01000007_gene308	1.27e-09	53.9	2EFWG@1|root,339NR@2|Bacteria,1NIWH@1224|Proteobacteria,1SHRN@1236|Gammaproteobacteria,1XZM2@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_3577_2	1187848.AJYQ01000102_gene1013	6.6e-113	334.0	COG1344@1|root,COG1344@2|Bacteria,1MV1N@1224|Proteobacteria,1RN0Y@1236|Gammaproteobacteria,1XSDK@135623|Vibrionales	135623|Vibrionales	N	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella	flaC	GO:0005575,GO:0005576,GO:0005623,GO:0009288,GO:0042995,GO:0043226,GO:0043228,GO:0044464	-	ko:K02406	ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flagellin_C,Flagellin_IN,Flagellin_N
k141_4937_2	1304885.AUEY01000004_gene1013	2.22e-91	276.0	COG1277@1|root,COG1277@2|Bacteria,1NZZ9@1224|Proteobacteria,42SH9@68525|delta/epsilon subdivisions,2WPWW@28221|Deltaproteobacteria,2MIHA@213118|Desulfobacterales	28221|Deltaproteobacteria	N	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC2_membrane_3,ABC_transp_aux
k141_4937_3	1120963.KB894502_gene1363	5.51e-51	189.0	COG3225@1|root,COG3225@2|Bacteria,1MY63@1224|Proteobacteria,1RP5E@1236|Gammaproteobacteria,2Q3ZH@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	N	ABC-type uncharacterized transport system	-	-	-	-	-	-	-	-	-	-	-	-	ABC_transp_aux
k141_1245_64	1033743.CAES01000111_gene1459	6.43e-53	168.0	COG0051@1|root,COG0051@2|Bacteria,1V6C9@1239|Firmicutes,4HIKH@91061|Bacilli,26XCR@186822|Paenibacillaceae	91061|Bacilli	J	Involved in the binding of tRNA to the ribosomes	rpsJ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02946	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S10
k141_1245_65	525919.Apre_0638	7.27e-44	166.0	COG2843@1|root,COG2843@2|Bacteria,1UZW4@1239|Firmicutes,24950@186801|Clostridia,22G4T@1570339|Peptoniphilaceae	186801|Clostridia	M	Bacterial capsule synthesis protein	capA	-	-	ko:K07282	-	-	-	-	ko00000	-	-	-	PGA_cap
k141_1245_68	1267580.AF6_2688	3.17e-12	61.6	COG4317@1|root,COG4317@2|Bacteria,1VKJ6@1239|Firmicutes,4HR5W@91061|Bacilli,21X82@150247|Anoxybacillus	91061|Bacilli	S	Protein of unknown function (DUF1427)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1427
k141_2510_1	316067.Geob_3309	8.04e-87	299.0	COG1657@1|root,COG4932@1|root,COG1657@2|Bacteria,COG4932@2|Bacteria,1PF83@1224|Proteobacteria,430QE@68525|delta/epsilon subdivisions	1224|Proteobacteria	M	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
k141_796_3	945543.VIBR0546_05254	3.81e-110	320.0	COG0344@1|root,COG0344@2|Bacteria,1RD4Z@1224|Proteobacteria,1RN1J@1236|Gammaproteobacteria,1XT3Z@135623|Vibrionales	135623|Vibrionales	I	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP	plsY	-	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	G3P_acyltransf
k141_4241_1	313596.RB2501_14179	3.83e-58	203.0	COG2203@1|root,COG3604@1|root,COG5000@1|root,COG2203@2|Bacteria,COG3604@2|Bacteria,COG5000@2|Bacteria,4PMAT@976|Bacteroidetes,1IJPS@117743|Flavobacteriia	976|Bacteroidetes	KT	Sigma-54 interaction domain	-	-	-	ko:K02584	ko02020,map02020	-	-	-	ko00000,ko00001,ko03000	-	-	-	GAF,GAF_2,GAF_3,HTH_8,PAS_9,Response_reg,Sigma54_activat
k141_1536_1	945543.VIBR0546_06527	5.3e-05	43.1	2AWQZ@1|root,31NMX@2|Bacteria,1QKCG@1224|Proteobacteria,1TIG0@1236|Gammaproteobacteria,1XZ2D@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_1536_2	55601.VANGNB10_cI0127c	1.67e-57	206.0	COG1388@1|root,COG3266@1|root,COG1388@2|Bacteria,COG3266@2|Bacteria,1RC2P@1224|Proteobacteria,1T2A3@1236|Gammaproteobacteria,1XSVD@135623|Vibrionales	135623|Vibrionales	M	LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	Pyocin_S
k141_3935_1	1122134.KB893650_gene168	9.79e-89	271.0	COG2126@1|root,COG2126@2|Bacteria,1MXCS@1224|Proteobacteria,1RPCN@1236|Gammaproteobacteria,1XIEA@135619|Oceanospirillales	135619|Oceanospirillales	J	COG1226 Kef-type K transport systems	-	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans
k141_3935_2	1380394.JADL01000001_gene2255	5.51e-32	126.0	COG0500@1|root,COG2226@2|Bacteria,1R6ZI@1224|Proteobacteria,2TRC6@28211|Alphaproteobacteria,2JT16@204441|Rhodospirillales	204441|Rhodospirillales	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
k141_2511_1	1187848.AJYQ01000032_gene2277	4.12e-79	251.0	COG2265@1|root,COG2265@2|Bacteria,1MV3A@1224|Proteobacteria,1RN1D@1236|Gammaproteobacteria,1XUN9@135623|Vibrionales	135623|Vibrionales	J	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA	rlmD	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TRAM,tRNA_U5-meth_tr
k141_3605_1	1565314.OA34_08200	3.19e-25	114.0	COG2244@1|root,COG2244@2|Bacteria,1MUN5@1224|Proteobacteria,42MH6@68525|delta/epsilon subdivisions,2YR4D@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_C
k141_3605_2	1449076.JOOE01000002_gene1109	1.52e-09	68.2	COG3307@1|root,COG3307@2|Bacteria,1R5EX@1224|Proteobacteria,2TTQF@28211|Alphaproteobacteria,2K3IA@204457|Sphingomonadales	204457|Sphingomonadales	M	O-Antigen ligase	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
k141_798_1	1322246.BN4_11821	4.88e-63	219.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42KZR@68525|delta/epsilon subdivisions,2WJ2T@28221|Deltaproteobacteria,2M7RA@213115|Desulfovibrionales	28221|Deltaproteobacteria	NT	PFAM chemotaxis	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HBM,MCPsignal
k141_2512_1	1033743.CAES01000047_gene650	4.21e-14	79.0	COG0860@1|root,COG0860@2|Bacteria,1V5SF@1239|Firmicutes,4HJNA@91061|Bacilli,26RP7@186822|Paenibacillaceae	91061|Bacilli	M	N-acetylmuramoyl-L-alanine amidase	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	AMIN,Amidase_3,Cu_amine_oxidN1
k141_2512_2	177437.HRM2_04340	5.37e-15	69.7	COG1366@1|root,COG1366@2|Bacteria,1NDC7@1224|Proteobacteria,42U42@68525|delta/epsilon subdivisions,2WR39@28221|Deltaproteobacteria,2MKS5@213118|Desulfobacterales	28221|Deltaproteobacteria	T	STAS domain	-	-	-	-	-	-	-	-	-	-	-	-	STAS,STAS_2
k141_1246_2	251229.Chro_3661	2.66e-126	411.0	COG0500@1|root,COG1020@1|root,COG0500@2|Bacteria,COG1020@2|Bacteria,1GBN8@1117|Cyanobacteria	1117|Cyanobacteria	Q	PFAM Phosphopantetheine attachment site	-	-	-	ko:K12240	ko01053,map01053	-	-	-	ko00000,ko00001,ko01008	-	-	-	AMP-binding,AMP-binding_C,Condensation,Methyltransf_12,PP-binding
k141_4242_1	935840.JAEQ01000006_gene2612	3.59e-62	202.0	COG0084@1|root,COG0084@2|Bacteria,1R450@1224|Proteobacteria,2TUDR@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	TatD-related deoxyribonuclease	-	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
k141_4242_2	13690.CP98_03094	1.01e-104	324.0	COG0603@1|root,COG0603@2|Bacteria,1MXFU@1224|Proteobacteria,2U0CR@28211|Alphaproteobacteria,2K5BX@204457|Sphingomonadales	204457|Sphingomonadales	F	PP-loop superfamily ATPase	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_282_1	177437.HRM2_28500	1.07e-112	333.0	COG0226@1|root,COG0226@2|Bacteria,1MVXP@1224|Proteobacteria,42PP7@68525|delta/epsilon subdivisions,2WJ4T@28221|Deltaproteobacteria,2MJBR@213118|Desulfobacterales	28221|Deltaproteobacteria	P	PBP superfamily domain	-	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
k141_282_2	56780.SYN_02225	7.66e-64	206.0	COG0573@1|root,COG0573@2|Bacteria,1MVKP@1224|Proteobacteria,42QHM@68525|delta/epsilon subdivisions,2WJ1B@28221|Deltaproteobacteria,2MRF2@213462|Syntrophobacterales	28221|Deltaproteobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
k141_282_3	98439.AJLL01000005_gene4452	1.25e-13	77.8	COG0581@1|root,COG0581@2|Bacteria,1G2GA@1117|Cyanobacteria,1JHYX@1189|Stigonemataceae	1117|Cyanobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
k141_282_4	471854.Dfer_4910	7.07e-20	95.9	COG2274@1|root,COG2274@2|Bacteria,4NE19@976|Bacteroidetes,47JYM@768503|Cytophagia	976|Bacteroidetes	V	ABC transporter transmembrane region	-	-	-	ko:K20344	ko02010,ko02024,map02010,map02024	-	-	-	ko00000,ko00001,ko02000	3.A.1.112	-	-	ABC_membrane,ABC_tran,Peptidase_C39
k141_282_5	153948.NAL212_1049	2.98e-11	68.2	COG3531@1|root,COG3531@2|Bacteria,1RIN9@1224|Proteobacteria,2VSP5@28216|Betaproteobacteria,3734F@32003|Nitrosomonadales	28216|Betaproteobacteria	O	Thioredoxin	-	-	-	ko:K07396	-	-	-	-	ko00000	-	-	-	DSBA,Thioredoxin_5
k141_282_6	485915.Dret_1056	1e-127	373.0	COG2113@1|root,COG2113@2|Bacteria,1R5CU@1224|Proteobacteria,42Z8G@68525|delta/epsilon subdivisions,2WU1W@28221|Deltaproteobacteria,2MACI@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	Substrate binding domain of ABC-type glycine betaine transport system	-	-	-	ko:K02002	ko02010,map02010	M00208	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	OpuAC
k141_282_7	485915.Dret_1055	7.15e-261	728.0	COG1292@1|root,COG1292@2|Bacteria,1MV0K@1224|Proteobacteria,42N6Q@68525|delta/epsilon subdivisions,2WJVG@28221|Deltaproteobacteria,2M7XM@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	Belongs to the BCCT transporter (TC 2.A.15) family	-	-	-	ko:K02168,ko:K03451	-	-	-	-	ko00000,ko02000	2.A.15,2.A.15.1.3,2.A.15.1.4	-	-	BCCT
k141_282_8	485915.Dret_1054	3.26e-29	108.0	28ZX4@1|root,2ZMMK@2|Bacteria,1P9RA@1224|Proteobacteria,433FN@68525|delta/epsilon subdivisions,2WXGW@28221|Deltaproteobacteria,2MC8U@213115|Desulfovibrionales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_570_1	400668.Mmwyl1_1192	1.15e-246	729.0	COG1388@1|root,COG1388@2|Bacteria,1P36H@1224|Proteobacteria	1224|Proteobacteria	M	LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	LysM
k141_570_2	1005395.CSV86_27052	4.05e-06	52.8	COG1716@1|root,COG1716@2|Bacteria,1NC3A@1224|Proteobacteria,1SDNF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Domain of unknown function (DUF4123)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4123
k141_2234_1	314292.VAS14_00781	2.34e-134	392.0	COG3829@1|root,COG3829@2|Bacteria,1QUPP@1224|Proteobacteria,1T3RG@1236|Gammaproteobacteria,1Y362@135623|Vibrionales	135623|Vibrionales	K	Bacterial regulatory protein, Fis family	pspF	-	-	ko:K03974	-	-	-	-	ko00000,ko03000	-	-	-	HTH_8,Sigma54_activat
k141_2234_2	1348635.BBJY01000004_gene3096	4.58e-255	714.0	COG4166@1|root,COG4166@2|Bacteria,1P91R@1224|Proteobacteria,1T1RS@1236|Gammaproteobacteria,1XUUH@135623|Vibrionales	135623|Vibrionales	E	COG4166 ABC-type oligopeptide transport system, periplasmic component	sapA	-	-	ko:K19226	ko01503,ko02010,map01503,map02010	M00739	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.5	-	-	SBP_bac_5
k141_3606_1	1121904.ARBP01000011_gene1465	8e-82	271.0	COG0841@1|root,COG0841@2|Bacteria,4NDZG@976|Bacteroidetes,47JGB@768503|Cytophagia	976|Bacteroidetes	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
k141_799_1	933262.AXAM01000009_gene1461	2.01e-115	349.0	COG1672@1|root,COG1672@2|Bacteria,1N4VD@1224|Proteobacteria,42Y71@68525|delta/epsilon subdivisions,2WTK1@28221|Deltaproteobacteria,2MMHF@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Predicted AAA-ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA-ATPase_like,PDDEXK_9
k141_5201_2	870967.VIS19158_04456	3.27e-68	210.0	COG2927@1|root,COG2927@2|Bacteria,1MZ3V@1224|Proteobacteria,1S697@1236|Gammaproteobacteria,1XX1X@135623|Vibrionales	135623|Vibrionales	L	DNA polymerase III chi subunit	holC	-	2.7.7.7	ko:K02339	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_chi
k141_5201_3	55601.VANGNB10_cI2256	0.0	924.0	COG0260@1|root,COG0260@2|Bacteria,1MUF9@1224|Proteobacteria,1RNM1@1236|Gammaproteobacteria,1XT1U@135623|Vibrionales	135623|Vibrionales	E	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides	pepA	-	3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17,Peptidase_M17_N
k141_5201_4	675806.VII_001368	6.99e-209	583.0	COG0795@1|root,COG0795@2|Bacteria,1MUF2@1224|Proteobacteria,1RMN5@1236|Gammaproteobacteria,1XSK9@135623|Vibrionales	135623|Vibrionales	S	Predicted permease YjgP/YjgQ family	lptF	-	-	ko:K07091	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
k141_5201_5	675813.VIB_000626	1.42e-196	551.0	COG0795@1|root,COG0795@2|Bacteria,1MVW3@1224|Proteobacteria,1RM8H@1236|Gammaproteobacteria,1XTBS@135623|Vibrionales	135623|Vibrionales	S	Predicted permease YjgP/YjgQ family	lptG	-	-	ko:K11720	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
k141_5201_7	945550.VISI1226_22560	2.35e-231	645.0	COG2206@1|root,COG2206@2|Bacteria,1N5T4@1224|Proteobacteria,1RZIM@1236|Gammaproteobacteria,1XSDW@135623|Vibrionales	135623|Vibrionales	T	HD-GYP domain-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF3391,HD
k141_1540_1	891974.E05_26800	1.56e-39	152.0	COG2373@1|root,COG2373@2|Bacteria,1MV7J@1224|Proteobacteria,1RNRY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	Large extracellular alpha-helical protein	yfhM	GO:0003674,GO:0004857,GO:0004866,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0009892,GO:0009897,GO:0009986,GO:0010466,GO:0010605,GO:0010951,GO:0016020,GO:0019222,GO:0030162,GO:0030234,GO:0030414,GO:0031224,GO:0031225,GO:0031226,GO:0031233,GO:0031323,GO:0031324,GO:0031362,GO:0032268,GO:0032269,GO:0043086,GO:0044092,GO:0044425,GO:0044459,GO:0044464,GO:0045861,GO:0046658,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0051336,GO:0051346,GO:0052547,GO:0052548,GO:0060255,GO:0061134,GO:0061135,GO:0065007,GO:0065009,GO:0071944,GO:0080090,GO:0098552,GO:0098772	-	ko:K06894	-	-	-	-	ko00000	-	-	-	A2M,A2M_N,A2M_N_2,A2M_comp,MG1,Thiol-ester_cl
k141_800_1	159749.K0SBU2	8.59e-11	64.3	COG0104@1|root,KOG1355@2759|Eukaryota,2XA6D@2836|Bacillariophyta	2836|Bacillariophyta	F	Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first	-	-	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
k141_800_2	96561.Dole_1232	8.31e-77	234.0	COG1139@1|root,COG1139@2|Bacteria,1RIJX@1224|Proteobacteria,42PGB@68525|delta/epsilon subdivisions,2WK1F@28221|Deltaproteobacteria,2MIYD@213118|Desulfobacterales	28221|Deltaproteobacteria	C	LUD domain	-	-	-	-	-	-	-	-	-	-	-	-	LUD_dom
k141_3607_1	1437824.BN940_18101	9.76e-07	57.0	COG0715@1|root,COG0715@2|Bacteria,1N19G@1224|Proteobacteria,2VRAC@28216|Betaproteobacteria,3T4FF@506|Alcaligenaceae	28216|Betaproteobacteria	P	NMT1/THI5 like	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1,TAT_signal
k141_3607_2	1121403.AUCV01000017_gene4515	1.06e-43	154.0	COG0500@1|root,COG0500@2|Bacteria,1QW86@1224|Proteobacteria,43CRZ@68525|delta/epsilon subdivisions,2WN4Z@28221|Deltaproteobacteria,2MKT1@213118|Desulfobacterales	28221|Deltaproteobacteria	Q	O-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Dimerisation2,Methyltransf_2
k141_2235_1	945543.VIBR0546_08284	5.78e-88	262.0	COG4635@1|root,COG4635@2|Bacteria,1RAH2@1224|Proteobacteria,1S372@1236|Gammaproteobacteria,1XSWA@135623|Vibrionales	135623|Vibrionales	CH	protoporphyrinogen oxidase	hemG	-	1.3.5.3	ko:K00230	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R09489	RC00885	ko00000,ko00001,ko00002,ko01000	-	-	-	Flavodoxin_5
k141_2235_2	243277.VC_2756	2e-213	599.0	COG0168@1|root,COG0168@2|Bacteria,1MUIJ@1224|Proteobacteria,1RMN6@1236|Gammaproteobacteria,1XU4M@135623|Vibrionales	135623|Vibrionales	P	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA	trkH	GO:0003674,GO:0005215,GO:0005216,GO:0005261,GO:0005267,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015267,GO:0015318,GO:0015672,GO:0016020,GO:0016021,GO:0022803,GO:0022838,GO:0022857,GO:0022890,GO:0030001,GO:0030955,GO:0031224,GO:0031226,GO:0031420,GO:0034220,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0044425,GO:0044459,GO:0044464,GO:0046872,GO:0046873,GO:0046983,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0098655,GO:0098660,GO:0098662	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
k141_801_1	1121405.dsmv_3261	1.93e-115	343.0	COG0484@1|root,COG0705@1|root,COG0484@2|Bacteria,COG0705@2|Bacteria,1MYFP@1224|Proteobacteria,42P0V@68525|delta/epsilon subdivisions,2WJGR@28221|Deltaproteobacteria,2MI6P@213118|Desulfobacterales	28221|Deltaproteobacteria	O	Rhomboid family	-	-	-	ko:K07059	-	-	-	-	ko00000	-	-	-	DnaJ_C,Rhomboid
k141_1247_2	675806.VII_001690	1.12e-270	750.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1T1IW@1236|Gammaproteobacteria,1XT5N@135623|Vibrionales	135623|Vibrionales	T	COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains	flaK	-	-	ko:K10941	ko02020,ko02025,ko05111,map02020,map02025,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	FleQ,HTH_8,Sigma54_activat
k141_1247_3	675806.VII_001691	1.75e-64	206.0	COG5000@1|root,COG5000@2|Bacteria,1QUG9@1224|Proteobacteria,1T1Y1@1236|Gammaproteobacteria,1XSAF@135623|Vibrionales	135623|Vibrionales	T	COG0642 Signal transduction histidine kinase	flrB	-	2.7.13.3	ko:K10942	ko02020,ko05111,map02020,map05111	M00515	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,PAS_8
k141_4950_1	536227.CcarbDRAFT_2794	3.3e-73	250.0	COG0840@1|root,COG0840@2|Bacteria,1TPI1@1239|Firmicutes,248XZ@186801|Clostridia,36FK2@31979|Clostridiaceae	186801|Clostridia	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal,dCache_1
k141_4950_4	500633.CLOHIR_02068	3.71e-112	325.0	COG0353@1|root,COG0353@2|Bacteria,1TR87@1239|Firmicutes,2487H@186801|Clostridia,25QKA@186804|Peptostreptococcaceae	186801|Clostridia	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	HHH,RecR,Toprim_4
k141_4950_5	457396.CSBG_03380	1.3e-36	127.0	COG0718@1|root,COG0718@2|Bacteria,1VA1S@1239|Firmicutes,24MXH@186801|Clostridia,36JG6@31979|Clostridiaceae	186801|Clostridia	S	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection	-	-	-	ko:K09747	-	-	-	-	ko00000	-	-	-	YbaB_DNA_bd
k141_4950_6	1476973.JMMB01000007_gene195	1.95e-176	515.0	COG2812@1|root,COG2812@2|Bacteria,1TPS9@1239|Firmicutes,247J7@186801|Clostridia,25QF4@186804|Peptostreptococcaceae	186801|Clostridia	H	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
k141_4950_7	869213.JCM21142_42031	4.32e-38	129.0	COG2158@1|root,COG2158@2|Bacteria	2|Bacteria	S	Cysteine-rich small domain	cbiA	-	-	ko:K07162	-	-	-	-	ko00000	-	-	-	zf-like
k141_4950_9	411465.PEPMIC_01545	9.35e-51	187.0	COG0642@1|root,COG5000@1|root,COG2205@2|Bacteria,COG5000@2|Bacteria,1V10X@1239|Firmicutes,24P7E@186801|Clostridia,22GWE@1570339|Peptoniphilaceae	186801|Clostridia	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein	phoR2	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
k141_4950_10	272563.CD630_17820	4.23e-83	254.0	COG0745@1|root,COG0745@2|Bacteria,1TPN8@1239|Firmicutes,248UA@186801|Clostridia,25QNR@186804|Peptostreptococcaceae	186801|Clostridia	KT	Response regulator receiver domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
k141_4950_11	767817.Desgi_3117	3.16e-09	67.4	COG0457@1|root,COG0457@2|Bacteria,1V54K@1239|Firmicutes,24JYK@186801|Clostridia	186801|Clostridia	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_2,TPR_8,VCBS
k141_4950_13	572479.Hprae_0193	5.75e-95	287.0	COG1108@1|root,COG1108@2|Bacteria,1TR79@1239|Firmicutes,24875@186801|Clostridia,3WBG5@53433|Halanaerobiales	186801|Clostridia	P	PFAM ABC 3 transport family	-	-	-	ko:K09816	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ABC-3
k141_4950_14	1121324.CLIT_20c00450	1.04e-62	204.0	COG1121@1|root,COG1121@2|Bacteria,1TQ68@1239|Firmicutes,248F1@186801|Clostridia	186801|Clostridia	P	Abc transporter	-	-	-	ko:K09817	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ABC_tran
k141_4950_15	1304284.L21TH_0421	8.21e-91	279.0	COG0803@1|root,COG0803@2|Bacteria,1TPG7@1239|Firmicutes,249VZ@186801|Clostridia,36EYU@31979|Clostridiaceae	186801|Clostridia	P	Belongs to the bacterial solute-binding protein 9 family	adcA	-	-	ko:K09815,ko:K09818	ko02010,map02010	M00242,M00243	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15,3.A.1.15.3,3.A.1.15.5	-	iHN637.CLJU_RS18655	ZnuA
k141_4950_17	1158614.I592_00575	3.69e-47	158.0	COG0590@1|root,COG0590@2|Bacteria,1V3HZ@1239|Firmicutes,4HH7S@91061|Bacilli,4B2BB@81852|Enterococcaceae	91061|Bacilli	F	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)	tadA	GO:0002097,GO:0002100,GO:0006139,GO:0006382,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016553,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360	3.5.4.33	ko:K11991	-	-	R10223	RC00477	ko00000,ko01000,ko03016	-	-	-	MafB19-deam
k141_4950_18	1444310.JANV01000138_gene1992	1.73e-56	191.0	COG1073@1|root,COG1073@2|Bacteria,1TQYU@1239|Firmicutes,4HC4H@91061|Bacilli,1ZBDV@1386|Bacillus	91061|Bacilli	S	COG1073 Hydrolases of the alpha beta superfamily	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Abhydrolase_1,Abhydrolase_6,Hydrolase_4
k141_4950_19	1121324.CLIT_4c01500	8.66e-44	147.0	2A59T@1|root,30TYZ@2|Bacteria,1UQ2N@1239|Firmicutes,24SKP@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_4950_20	1511.CLOST_2435	1.26e-47	186.0	COG4191@1|root,COG5001@1|root,COG4191@2|Bacteria,COG5001@2|Bacteria,1UCKT@1239|Firmicutes,24GBZ@186801|Clostridia	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
k141_4950_21	1480694.DC28_04470	1.21e-21	103.0	COG0683@1|root,COG0683@2|Bacteria,2JADP@203691|Spirochaetes	203691|Spirochaetes	E	Receptor family ligand binding region	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
k141_4950_22	1480694.DC28_04470	2.25e-37	147.0	COG0683@1|root,COG0683@2|Bacteria,2JADP@203691|Spirochaetes	203691|Spirochaetes	E	Receptor family ligand binding region	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
k141_4950_24	1480694.DC28_04470	2.39e-12	72.4	COG0683@1|root,COG0683@2|Bacteria,2JADP@203691|Spirochaetes	203691|Spirochaetes	E	Receptor family ligand binding region	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
k141_4950_25	1480694.DC28_04470	2.37e-38	150.0	COG0683@1|root,COG0683@2|Bacteria,2JADP@203691|Spirochaetes	203691|Spirochaetes	E	Receptor family ligand binding region	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
k141_4950_26	1511.CLOST_0051	3.95e-228	637.0	COG0172@1|root,COG0172@2|Bacteria,1TP4W@1239|Firmicutes,2485M@186801|Clostridia,25QWP@186804|Peptostreptococcaceae	186801|Clostridia	J	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
k141_4950_27	332101.JIBU02000023_gene4644	5.59e-298	831.0	COG1299@1|root,COG1445@1|root,COG1762@1|root,COG1299@2|Bacteria,COG1445@2|Bacteria,COG1762@2|Bacteria,1TPKU@1239|Firmicutes,248V6@186801|Clostridia,36DXV@31979|Clostridiaceae	186801|Clostridia	G	PTS system, fructose subfamily	fruA	-	2.7.1.202	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	M00273	R03232	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.2.1	-	-	PTS_EIIA_2,PTS_EIIC,PTS_IIB
k141_4950_28	536227.CcarbDRAFT_0919	3.53e-104	313.0	COG1105@1|root,COG1105@2|Bacteria,1TQ36@1239|Firmicutes,249RK@186801|Clostridia,36DV1@31979|Clostridiaceae	186801|Clostridia	H	Belongs to the carbohydrate kinase PfkB family. LacC subfamily	pfkB	-	2.7.1.56	ko:K00882	ko00051,map00051	-	R02071	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
k141_4950_29	1380408.AVGH01000004_gene2326	2.14e-84	259.0	COG1349@1|root,COG1349@2|Bacteria,1TSF8@1239|Firmicutes,4HDT9@91061|Bacilli,21V0J@150247|Anoxybacillus	91061|Bacilli	K	DeoR C terminal sensor domain	fruR	-	-	ko:K03436	-	-	-	-	ko00000,ko03000	-	-	-	DeoRC,HTH_DeoR
k141_2236_1	1415775.U729_2421	2.62e-07	52.4	COG0745@1|root,COG0745@2|Bacteria,1TQ0D@1239|Firmicutes,248WX@186801|Clostridia,36FU1@31979|Clostridiaceae	186801|Clostridia	T	Regulatory protein	spaR	-	-	ko:K20488	ko02020,ko02024,map02020,map02024	M00816	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
k141_5346_30	1391646.AVSU01000025_gene2434	5.15e-189	535.0	COG0743@1|root,COG0743@2|Bacteria,1TP1C@1239|Firmicutes,2483M@186801|Clostridia,25QE4@186804|Peptostreptococcaceae	186801|Clostridia	I	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)	dxr	-	1.1.1.267	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05688	RC01452	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS06420	DXPR_C,DXP_redisom_C,DXP_reductoisom
k141_5346_31	272563.CD630_21350	6.9e-67	215.0	COG4589@1|root,COG4589@2|Bacteria,1TT0Q@1239|Firmicutes,25HJP@186801|Clostridia,25QVC@186804|Peptostreptococcaceae	186801|Clostridia	S	Belongs to the CDS family	cdsA	-	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
k141_5346_32	521097.Coch_1356	2.64e-81	250.0	COG0020@1|root,COG0020@2|Bacteria,4NF2B@976|Bacteroidetes,1HXRP@117743|Flavobacteriia,1EQBN@1016|Capnocytophaga	976|Bacteroidetes	H	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	uppS	GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
k141_5346_34	1286171.EAL2_c13330	2.97e-81	246.0	COG0233@1|root,COG0233@2|Bacteria,1V1F2@1239|Firmicutes,24HWS@186801|Clostridia,25WFH@186806|Eubacteriaceae	186801|Clostridia	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	-	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
k141_5346_35	1511.CLOST_1703	2.32e-115	336.0	COG0528@1|root,COG0528@2|Bacteria,1TPXN@1239|Firmicutes,247KR@186801|Clostridia,25R1E@186804|Peptostreptococcaceae	186801|Clostridia	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	-	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
k141_5346_36	500633.CLOHIR_01275	2.9e-132	384.0	COG0264@1|root,COG0264@2|Bacteria,1TPFJ@1239|Firmicutes,248J2@186801|Clostridia,25R59@186804|Peptostreptococcaceae	186801|Clostridia	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	-	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
k141_5346_37	1121324.CLIT_11c02210	1.57e-134	385.0	COG0052@1|root,COG0052@2|Bacteria,1TPNA@1239|Firmicutes,247ZR@186801|Clostridia,25QY9@186804|Peptostreptococcaceae	186801|Clostridia	J	Belongs to the universal ribosomal protein uS2 family	rpsB	-	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
k141_5346_40	1286171.EAL2_c13370	4.89e-106	330.0	COG1315@1|root,COG1315@2|Bacteria,1TR7W@1239|Firmicutes,24B18@186801|Clostridia,25VT9@186806|Eubacteriaceae	186801|Clostridia	L	Pfam:DUF342	-	-	-	ko:K09749	-	-	-	-	ko00000	-	-	-	FapA
k141_5346_41	1511.CLOST_1709	1.25e-88	269.0	COG1191@1|root,COG1191@2|Bacteria,1TP9K@1239|Firmicutes,248M0@186801|Clostridia,25SNQ@186804|Peptostreptococcaceae	186801|Clostridia	K	Sigma-70 region 3	fliA	-	-	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	-	-	-	ko00000,ko00001,ko02035,ko03021	-	-	-	Sigma70_r2,Sigma70_r3,Sigma70_r4
k141_5346_43	1121324.CLIT_11c02170	2.14e-76	231.0	COG1871@1|root,COG1871@2|Bacteria,1V70X@1239|Firmicutes,24HH7@186801|Clostridia	186801|Clostridia	NT	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis	cheD	-	3.5.1.44	ko:K03411	ko02030,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheD
k141_5346_44	1304284.L21TH_2260	3.37e-63	202.0	COG1776@1|root,COG1776@2|Bacteria,1UNKB@1239|Firmicutes,247MX@186801|Clostridia,36H30@31979|Clostridiaceae	186801|Clostridia	NT	chemotaxis protein	cheC	-	-	ko:K03410	ko02030,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheC
k141_5346_45	1121324.CLIT_11c02150	2.72e-55	177.0	COG0835@1|root,COG0835@2|Bacteria,1V4HH@1239|Firmicutes,24JV4@186801|Clostridia	186801|Clostridia	NT	PFAM CheW domain protein	cheW2	-	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
k141_5346_46	1121324.CLIT_11c02140	4.31e-290	816.0	COG0643@1|root,COG0643@2|Bacteria,1TPMS@1239|Firmicutes,24858@186801|Clostridia	186801|Clostridia	T	Signal transducing histidine kinase homodimeric	cheA	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt,P2
k141_5346_47	634956.Geoth_2679	4.34e-111	335.0	COG2201@1|root,COG2201@2|Bacteria,1TRHC@1239|Firmicutes,4HBJY@91061|Bacilli,1WEHZ@129337|Geobacillus	91061|Bacilli	NT	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR	cheB	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	3.1.1.61,3.5.1.44	ko:K03412	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,Response_reg
k141_5346_48	1286171.EAL2_c13450	3.85e-45	156.0	COG5581@1|root,COG5581@2|Bacteria	2|Bacteria	M	regulation of bacterial-type flagellum-dependent cell motility by regulation of motor speed	pilZ	-	-	-	-	-	-	-	-	-	-	-	PilZ,YcgR_2
k141_5346_49	1121324.CLIT_11c02110	2.38e-98	298.0	COG0455@1|root,COG0455@2|Bacteria,1TRZ5@1239|Firmicutes,24AIN@186801|Clostridia	186801|Clostridia	D	Belongs to the ParA family	flhG	-	-	ko:K04562	-	-	-	-	ko00000,ko02035	-	-	-	AAA_31,CbiA,ParA
k141_5346_50	864565.HMPREF0379_0477	4.66e-86	276.0	COG1419@1|root,COG1419@2|Bacteria,1TSP7@1239|Firmicutes,249R1@186801|Clostridia,25SRR@186804|Peptostreptococcaceae	186801|Clostridia	N	SRP54-type protein, GTPase domain	flhF	-	-	ko:K02404	-	-	-	-	ko00000,ko02035	-	-	-	SRP54
k141_5346_51	1121324.CLIT_11c02090	0.0	937.0	COG1298@1|root,COG1298@2|Bacteria,1TQBM@1239|Firmicutes,248F5@186801|Clostridia	186801|Clostridia	N	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin	flhA	-	-	ko:K02400	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	FHIPEP
k141_5346_52	1286171.EAL2_c13490	1.38e-122	364.0	COG1377@1|root,COG1377@2|Bacteria,1TPRP@1239|Firmicutes,248N7@186801|Clostridia,25VUQ@186806|Eubacteriaceae	186801|Clostridia	N	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin	flhB	-	-	ko:K02401,ko:K13820	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	Bac_export_1,Bac_export_2
k141_5346_53	1286171.EAL2_c13500	1.04e-56	189.0	COG1684@1|root,COG1684@2|Bacteria,1TRB2@1239|Firmicutes,24ECW@186801|Clostridia,25WZS@186806|Eubacteriaceae	186801|Clostridia	N	flagellar biosynthetic protein FliR	fliR	-	-	ko:K02421	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	Bac_export_1
k141_5346_54	1121324.CLIT_11c02060	5.12e-31	111.0	COG1987@1|root,COG1987@2|Bacteria,1VEHF@1239|Firmicutes,24QJR@186801|Clostridia,25TZT@186804|Peptostreptococcaceae	186801|Clostridia	N	Role in flagellar biosynthesis	fliQ	-	-	ko:K02420	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	Bac_export_3
k141_5346_55	1121324.CLIT_11c02050	3.1e-97	291.0	COG1338@1|root,COG1338@2|Bacteria,1TPIE@1239|Firmicutes,2487C@186801|Clostridia,25STK@186804|Peptostreptococcaceae	186801|Clostridia	N	Plays a role in the flagellum-specific transport system	fliP	-	-	ko:K02419	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	FliP
k141_3384_11	999541.bgla_2g12490	3.32e-77	260.0	COG3497@1|root,COG3497@2|Bacteria,1MX89@1224|Proteobacteria,2VM4U@28216|Betaproteobacteria,1K9P6@119060|Burkholderiaceae	28216|Betaproteobacteria	S	COG Phage tail sheath protein FI	-	-	-	ko:K06907	-	-	-	-	ko00000	-	-	-	Phage_sheath_1,Phage_sheath_1C
k141_3384_12	1476583.DEIPH_ctg009orf0012	1.23e-22	94.4	2ACY3@1|root,312JQ@2|Bacteria	2|Bacteria	S	T4-like virus tail tube protein gp19	-	-	-	-	-	-	-	-	-	-	-	-	Phage_T4_gp19
k141_3384_13	1200792.AKYF01000018_gene5793	1.66e-48	158.0	arCOG11412@1|root,31S84@2|Bacteria,1V6H1@1239|Firmicutes,4HJGG@91061|Bacilli,26XZS@186822|Paenibacillaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_3384_14	1227352.C173_31931	9.65e-42	143.0	2DMQT@1|root,32T2H@2|Bacteria,1VA81@1239|Firmicutes,4HM02@91061|Bacilli,26Y64@186822|Paenibacillaceae	91061|Bacilli	S	T4-like virus tail tube protein gp19	-	-	-	-	-	-	-	-	-	-	-	-	Phage_T4_gp19
k141_3386_1	879212.DespoDRAFT_01093	2.96e-21	88.2	COG1314@1|root,COG1314@2|Bacteria,1NJ1D@1224|Proteobacteria,42TKW@68525|delta/epsilon subdivisions,2WRA3@28221|Deltaproteobacteria,2MKYR@213118|Desulfobacterales	28221|Deltaproteobacteria	U	PFAM Preprotein translocase SecG subunit	secG	-	-	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecG
k141_3386_2	517418.Ctha_0537	2.02e-78	244.0	COG0149@1|root,COG0149@2|Bacteria,1FDS9@1090|Chlorobi	1090|Chlorobi	F	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	-	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
k141_3386_3	96561.Dole_0500	1.65e-118	348.0	COG0057@1|root,COG0057@2|Bacteria,1MU93@1224|Proteobacteria,42N9Q@68525|delta/epsilon subdivisions,2WIK1@28221|Deltaproteobacteria,2MIIT@213118|Desulfobacterales	28221|Deltaproteobacteria	G	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	gap	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
k141_3387_1	55601.VANGNB10_cI2099c	2.3e-211	611.0	COG0507@1|root,COG0507@2|Bacteria,1MW43@1224|Proteobacteria,1RPA0@1236|Gammaproteobacteria,1XTSQ@135623|Vibrionales	135623|Vibrionales	L	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD	recD	-	3.1.11.5	ko:K03581	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AAA_30,UvrD_C_2
k141_3387_2	243277.VC_2318	1.25e-24	93.2	2B2RH@1|root,31VBN@2|Bacteria,1QT8K@1224|Proteobacteria,1TIC2@1236|Gammaproteobacteria,1XYUI@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_3388_2	675813.VIB_001228	7.61e-53	172.0	COG3637@1|root,COG3637@2|Bacteria,1RHVI@1224|Proteobacteria,1S6UY@1236|Gammaproteobacteria,1XVZ1@135623|Vibrionales	135623|Vibrionales	M	OmpA-like transmembrane domain	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl
k141_3388_3	573.JG24_17070	4.16e-63	204.0	COG2390@1|root,COG2390@2|Bacteria,1MWHQ@1224|Proteobacteria,1RRDZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	transcriptional regulator	lsrR_2	-	-	ko:K11531	ko02024,ko02026,map02024,map02026	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_23,Sigma70_r4_2,Sugar-bind
k141_3391_1	675815.VOA_002961	1.13e-104	308.0	COG3642@1|root,COG3642@2|Bacteria,1RDW7@1224|Proteobacteria,1S46R@1236|Gammaproteobacteria,1XT1W@135623|Vibrionales	135623|Vibrionales	H	Catalyzes the ATP-dependent phosphorylation of the 3- deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position	kdkA	-	2.7.1.166	ko:K11211	ko00540,map00540	-	R09767	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	Kdo
k141_3391_2	945543.VIBR0546_16336	2.56e-187	528.0	COG0859@1|root,COG0859@2|Bacteria,1MYZA@1224|Proteobacteria,1RR6K@1236|Gammaproteobacteria,1XSR4@135623|Vibrionales	135623|Vibrionales	M	COG0859 ADP-heptose LPS heptosyltransferase	-	-	-	ko:K12982	-	-	-	-	ko00000,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
k141_3391_4	945543.VIBR0546_16326	4.49e-187	526.0	COG0859@1|root,COG0859@2|Bacteria,1N5A1@1224|Proteobacteria,1RYYI@1236|Gammaproteobacteria,1XU8P@135623|Vibrionales	135623|Vibrionales	M	ADP-heptose-LPS heptosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_9
k141_3391_5	945543.VIBR0546_16321	1.49e-89	265.0	COG0669@1|root,COG0669@2|Bacteria,1RD9F@1224|Proteobacteria,1S41J@1236|Gammaproteobacteria,1XUJI@135623|Vibrionales	135623|Vibrionales	H	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	GO:0003674,GO:0003824,GO:0004595,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
k141_3392_1	1026882.MAMP_02936	1.99e-30	118.0	COG0609@1|root,COG0609@2|Bacteria,1MV9W@1224|Proteobacteria,1RMDF@1236|Gammaproteobacteria,460DW@72273|Thiotrichales	72273|Thiotrichales	P	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily	-	-	-	ko:K02015	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	FecCD
k141_3392_2	595460.RRSWK_04311	6.95e-44	167.0	COG1572@1|root,COG2264@1|root,COG3291@1|root,COG1572@2|Bacteria,COG2264@2|Bacteria,COG3291@2|Bacteria,2J503@203682|Planctomycetes	203682|Planctomycetes	J	Domain of unknown function (DUF4465)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4465,Dockerin_1
k141_3392_3	1449345.JHWC01000007_gene1287	5.13e-16	84.0	COG4206@1|root,COG4206@2|Bacteria,1MW63@1224|Proteobacteria,42PIU@68525|delta/epsilon subdivisions,2YNAZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	TonB dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
k141_3393_1	572547.Amico_0323	1.18e-54	202.0	COG0392@1|root,COG2898@1|root,COG0392@2|Bacteria,COG2898@2|Bacteria,3TAI7@508458|Synergistetes	508458|Synergistetes	S	Uncharacterised conserved protein (DUF2156)	-	-	2.3.2.3	ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	M00726	-	-	ko00000,ko00001,ko00002,ko01000,ko01504	2.A.1.3.37	-	-	DUF2156,LPG_synthase_TM
k141_3394_1	1433126.BN938_0887	8.32e-06	47.4	COG1811@1|root,COG1811@2|Bacteria,4NPXN@976|Bacteroidetes,2FSK6@200643|Bacteroidia,22VBU@171550|Rikenellaceae	976|Bacteroidetes	S	Protein of unknown function (DUF554)	-	-	-	ko:K07150	-	-	-	-	ko00000	-	-	-	DUF554
k141_3394_2	240015.ACP_3529	6.07e-30	117.0	COG1595@1|root,COG1595@2|Bacteria,3Y3BS@57723|Acidobacteria,2JIDF@204432|Acidobacteriia	57723|Acidobacteria	K	RNA polymerase sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
k141_3395_1	221027.JO40_00515	6.08e-164	489.0	COG0493@1|root,COG1902@1|root,COG0493@2|Bacteria,COG1902@2|Bacteria,2J6QD@203691|Spirochaetes	203691|Spirochaetes	C	NADH:flavin oxidoreductase / NADH oxidase family	-	-	1.3.1.31,1.3.1.34	ko:K00219,ko:K10797	ko00360,ko01120,map00360,map01120	-	R02252	RC00669	ko00000,ko00001,ko01000	-	-	-	Oxidored_FMN,Pyr_redox_2
k141_3396_1	1449337.JQLL01000001_gene28	1.25e-41	156.0	COG0577@1|root,COG1511@1|root,COG0577@2|Bacteria,COG1511@2|Bacteria,1TPHU@1239|Firmicutes,4HA2C@91061|Bacilli,27FQ2@186828|Carnobacteriaceae	91061|Bacilli	V	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
k141_3397_1	879212.DespoDRAFT_00228	1.2e-54	185.0	COG2199@1|root,COG3706@2|Bacteria,1MZV7@1224|Proteobacteria,42MCG@68525|delta/epsilon subdivisions,2WKEQ@28221|Deltaproteobacteria,2MIN9@213118|Desulfobacterales	28221|Deltaproteobacteria	T	TIGRFAM diguanylate cyclase (GGDEF) domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
k141_3397_2	56780.SYN_00970	1.26e-89	274.0	COG1352@1|root,COG1352@2|Bacteria,1MU6W@1224|Proteobacteria,42MR2@68525|delta/epsilon subdivisions,2WKKH@28221|Deltaproteobacteria,2MRQX@213462|Syntrophobacterales	28221|Deltaproteobacteria	NT	Methyltransferase, chemotaxis proteins	cheR34H	-	2.1.1.80	ko:K00575	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheR,CheR_N,Response_reg
k141_3397_3	1304885.AUEY01000009_gene1955	2.24e-188	559.0	COG0643@1|root,COG0643@2|Bacteria,1MUAG@1224|Proteobacteria,42M6Q@68525|delta/epsilon subdivisions,2WJ5U@28221|Deltaproteobacteria,2MHZP@213118|Desulfobacterales	28221|Deltaproteobacteria	NT	Signal transducing histidine kinase, homodimeric	-	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt
k141_3397_4	1304885.AUEY01000002_gene423	1.25e-78	236.0	COG1871@1|root,COG1871@2|Bacteria,1RAWA@1224|Proteobacteria,42QP1@68525|delta/epsilon subdivisions,2WQBY@28221|Deltaproteobacteria,2MJPU@213118|Desulfobacterales	28221|Deltaproteobacteria	NT	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis	cheD1	-	3.5.1.44	ko:K03411	ko02030,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheD
k141_3399_1	223926.28806178	2.27e-137	402.0	COG3604@1|root,COG3604@2|Bacteria,1QTT3@1224|Proteobacteria,1T1G7@1236|Gammaproteobacteria,1XSRB@135623|Vibrionales	135623|Vibrionales	K	COG3604 Transcriptional regulator containing GAF, AAA-type ATPase, and DNA binding domains	-	-	-	ko:K12266	ko05132,map05132	-	-	-	ko00000,ko00001,ko03000	-	-	-	GAF,HTH_8,Sigma54_activat
k141_5426_1	945543.VIBR0546_06687	1.8e-231	645.0	COG2206@1|root,COG2206@2|Bacteria,1N5T4@1224|Proteobacteria,1RZIM@1236|Gammaproteobacteria,1XSDW@135623|Vibrionales	135623|Vibrionales	T	HD-GYP domain-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF3391,HD
k141_5426_2	1219072.VHA01S_010_00360	5.69e-259	725.0	COG4166@1|root,COG4166@2|Bacteria,1P91R@1224|Proteobacteria,1RN57@1236|Gammaproteobacteria,1XVN1@135623|Vibrionales	135623|Vibrionales	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	SBP_bac_5
k141_5426_3	1524467.IV04_20280	3.2e-89	270.0	COG2866@1|root,COG2866@2|Bacteria,1N9AY@1224|Proteobacteria,1RRGU@1236|Gammaproteobacteria,3ZZX8@613|Serratia	1236|Gammaproteobacteria	E	Murein peptide amidase A	mpaA	GO:0000270,GO:0003674,GO:0003824,GO:0004040,GO:0004180,GO:0004181,GO:0005488,GO:0006022,GO:0006026,GO:0006027,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0008270,GO:0009050,GO:0009056,GO:0009057,GO:0009253,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0019538,GO:0030203,GO:0034641,GO:0043167,GO:0043169,GO:0043170,GO:0043171,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0046872,GO:0046914,GO:0061473,GO:0070011,GO:0071704,GO:0140096,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575	-	ko:K14054	-	-	-	-	ko00000	-	-	iEC55989_1330.EC55989_1490,iECO103_1326.ECO103_1491	Peptidase_M14
k141_5426_5	55601.VANGNB10_cI2254c	4.71e-195	548.0	COG0795@1|root,COG0795@2|Bacteria,1MVW3@1224|Proteobacteria,1RM8H@1236|Gammaproteobacteria,1XTBS@135623|Vibrionales	135623|Vibrionales	S	Predicted permease YjgP/YjgQ family	lptG	-	-	ko:K11720	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
k141_5426_8	1051646.VITU9109_08356	1.29e-61	193.0	COG2927@1|root,COG2927@2|Bacteria,1MZ3V@1224|Proteobacteria,1S697@1236|Gammaproteobacteria,1XX1X@135623|Vibrionales	135623|Vibrionales	L	DNA polymerase III chi subunit	holC	-	2.7.7.7	ko:K02339	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_chi
k141_5426_9	345073.VC395_2617	0.0	1749.0	COG0525@1|root,COG0525@2|Bacteria,1MV7B@1224|Proteobacteria,1RNEB@1236|Gammaproteobacteria,1XTVJ@135623|Vibrionales	135623|Vibrionales	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
k141_5426_10	55601.VANGNB10_cI2259c	3.47e-156	446.0	COG1052@1|root,COG1052@2|Bacteria,1MU2D@1224|Proteobacteria,1RPM1@1236|Gammaproteobacteria,1XTHS@135623|Vibrionales	135623|Vibrionales	C	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family	hprA	-	1.1.1.29	ko:K00018	ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200	M00346	R00717,R01388	RC00031,RC00042	ko00000,ko00001,ko00002,ko01000	-	-	-	2-Hacid_dh,2-Hacid_dh_C
k141_5426_11	675813.VIB_000620	1.33e-148	421.0	COG0564@1|root,COG0564@2|Bacteria,1MVJ5@1224|Proteobacteria,1RN4N@1236|Gammaproteobacteria,1XURW@135623|Vibrionales	135623|Vibrionales	J	Responsible for synthesis of pseudouridine from uracil	rluA	GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	5.4.99.28,5.4.99.29	ko:K06177	-	-	-	-	ko00000,ko01000,ko03009,ko03016	-	-	-	PseudoU_synth_2
k141_5426_12	55601.VANGNB10_cI2261	7.65e-214	601.0	COG1914@1|root,COG1914@2|Bacteria,1MWET@1224|Proteobacteria,1RY2N@1236|Gammaproteobacteria,1XW0V@135623|Vibrionales	135623|Vibrionales	P	Mn2 and Fe2 transporters of the NRAMP family	-	-	-	-	-	-	-	-	-	-	-	-	Nramp
k141_5426_14	345073.VC395_2621	2.33e-288	792.0	COG1875@1|root,COG1875@2|Bacteria,1MUX1@1224|Proteobacteria,1RMQN@1236|Gammaproteobacteria,1XTED@135623|Vibrionales	135623|Vibrionales	T	ATPase related to phosphate starvation-inducible protein PhoH	-	-	-	ko:K07175	-	-	-	-	ko00000	-	-	-	PIN_4,PhoH
k141_5426_17	223926.28807665	1.06e-91	270.0	COG1781@1|root,COG1781@2|Bacteria,1RB7J@1224|Proteobacteria,1S2BM@1236|Gammaproteobacteria,1XSYU@135623|Vibrionales	135623|Vibrionales	F	Involved in allosteric regulation of aspartate carbamoyltransferase	pyrI	GO:0003674,GO:0003824,GO:0004070,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	-	ko:K00610	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002	-	-	-	PyrI,PyrI_C
k141_5426_19	1187848.AJYQ01000042_gene48	2.03e-126	365.0	COG0204@1|root,COG0204@2|Bacteria,1MY51@1224|Proteobacteria,1RQYC@1236|Gammaproteobacteria,1XTMX@135623|Vibrionales	135623|Vibrionales	I	Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family	plsC	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
k141_5426_21	55601.VANGNB10_cI2272c	7.13e-37	125.0	COG5007@1|root,COG5007@2|Bacteria,1N1WJ@1224|Proteobacteria,1SCAR@1236|Gammaproteobacteria,1XXSQ@135623|Vibrionales	135623|Vibrionales	K	Belongs to the BolA IbaG family	yrbA	-	-	-	-	-	-	-	-	-	-	-	BolA
k141_5426_22	223926.28807670	1.07e-38	132.0	COG3113@1|root,COG3113@2|Bacteria,1NGIE@1224|Proteobacteria,1SGH6@1236|Gammaproteobacteria,1XYDH@135623|Vibrionales	135623|Vibrionales	S	NTP binding protein (contains STAS domain)	yrbB	-	-	ko:K07122	ko02010,map02010	M00210	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27.3	-	-	STAS_2
k141_5426_23	575788.VS_2747	2.02e-85	259.0	COG2854@1|root,COG2854@2|Bacteria,1NKFA@1224|Proteobacteria,1RNJW@1236|Gammaproteobacteria,1XT3S@135623|Vibrionales	135623|Vibrionales	Q	ABC-type transport system involved in resistance to organic solvents, auxiliary component	mlaC	-	-	ko:K07323	ko02010,map02010	M00210	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27.3	-	-	MlaC
k141_5426_24	674977.VMC_34650	3.77e-81	244.0	COG1463@1|root,COG1463@2|Bacteria,1NCUG@1224|Proteobacteria,1RQ0Y@1236|Gammaproteobacteria,1XW1T@135623|Vibrionales	135623|Vibrionales	Q	abc-type transport system involved in resistance to organic solvents, periplasmic component	mlaD	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
k141_5426_29	672.VV93_v1c04200	4.1e-102	298.0	COG1778@1|root,COG1778@2|Bacteria,1RH85@1224|Proteobacteria,1S6D0@1236|Gammaproteobacteria,1XSN7@135623|Vibrionales	135623|Vibrionales	S	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate	kdsC	-	3.1.3.45	ko:K03270	ko00540,ko01100,map00540,map01100	M00063	R03350	RC00017	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hydrolase_3
k141_5426_30	243277.VC_2525	4.19e-89	266.0	COG3117@1|root,COG3117@2|Bacteria,1RA1Y@1224|Proteobacteria,1SDZE@1236|Gammaproteobacteria,1XSM1@135623|Vibrionales	135623|Vibrionales	S	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA	lptC	-	-	ko:K11719	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	LptC
k141_5426_35	55601.VANGNB10_cI2286	8.97e-77	231.0	COG1762@1|root,COG1762@2|Bacteria,1RD0E@1224|Proteobacteria,1S668@1236|Gammaproteobacteria,1XWXU@135623|Vibrionales	135623|Vibrionales	G	Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)	ptsN	-	-	ko:K02806	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	-	-	-	PTS_EIIA_2
k141_5426_36	345073.VC395_2645	6.07e-163	461.0	COG1660@1|root,COG1660@2|Bacteria,1MVX6@1224|Proteobacteria,1RNJX@1236|Gammaproteobacteria,1XSBH@135623|Vibrionales	135623|Vibrionales	S	Displays ATPase and GTPase activities	yhbJ	-	-	ko:K06958	-	-	-	-	ko00000,ko03019	-	-	-	ATP_bind_2
k141_5426_37	1348635.BBJY01000009_gene1653	8.18e-42	139.0	COG1925@1|root,COG1925@2|Bacteria,1N6RM@1224|Proteobacteria,1SCXX@1236|Gammaproteobacteria,1XYBI@135623|Vibrionales	135623|Vibrionales	G	COG1925 Phosphotransferase system, HPr-related proteins	ptsO	GO:0006808,GO:0006810,GO:0008150,GO:0008643,GO:0009401,GO:0050789,GO:0051179,GO:0051234,GO:0065007,GO:0071702	-	ko:K08485	ko02060,map02060	-	-	-	ko00000,ko00001,ko02000	-	-	-	PTS-HPr
k141_5426_39	945543.VIBR0546_01356	5.47e-263	727.0	COG0312@1|root,COG0312@2|Bacteria,1MUVW@1224|Proteobacteria,1RPJF@1236|Gammaproteobacteria,1XSU9@135623|Vibrionales	135623|Vibrionales	S	Zn-dependent proteases and their inactivated homologs	pmbA	-	-	ko:K03592	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
k141_5426_41	113355.CM001775_gene2373	1.95e-209	606.0	28PYV@1|root,2ZCIC@2|Bacteria,1GBG4@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_5426_42	1190606.AJYG01000056_gene728	1.56e-74	232.0	COG3840@1|root,COG3840@2|Bacteria,1MV78@1224|Proteobacteria,1RQH3@1236|Gammaproteobacteria,1XU4J@135623|Vibrionales	135623|Vibrionales	P	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system	thiQ	GO:0003674,GO:0003824,GO:0005215,GO:0006810,GO:0006855,GO:0008150,GO:0015234,GO:0015238,GO:0015399,GO:0015405,GO:0015888,GO:0015893,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0035461,GO:0042221,GO:0042493,GO:0042623,GO:0042626,GO:0043492,GO:0045117,GO:0050896,GO:0051179,GO:0051180,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071934,GO:0072348,GO:0072531,GO:0090482,GO:1901474,GO:1901682	-	ko:K02062	ko02010,map02010	M00191	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.19	-	-	ABC_tran
k141_5426_43	243277.VC_2538	3.52e-187	542.0	COG1178@1|root,COG1178@2|Bacteria,1MWCF@1224|Proteobacteria,1RNHK@1236|Gammaproteobacteria,1XT1Z@135623|Vibrionales	135623|Vibrionales	P	COG1178 ABC-type Fe3 transport system, permease component	thiP	-	-	ko:K02063	ko02010,map02010	M00191	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.19	-	-	BPD_transp_1
k141_5426_44	312309.VF_0267	1.95e-155	446.0	COG4143@1|root,COG4143@2|Bacteria,1MUBB@1224|Proteobacteria,1RMQ9@1236|Gammaproteobacteria,1XT2T@135623|Vibrionales	135623|Vibrionales	P	COG4143 ABC-type thiamine transport system, periplasmic component	tbpA	-	-	ko:K02064	ko02010,map02010	M00191	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.19	-	-	SBP_bac_1,SBP_bac_6
k141_5426_45	1280001.BAOA01000021_gene807	2.48e-101	298.0	COG0163@1|root,COG0163@2|Bacteria,1RA0P@1224|Proteobacteria,1RPN1@1236|Gammaproteobacteria,1XSI5@135623|Vibrionales	135623|Vibrionales	H	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN	ubiX	GO:0003674,GO:0003824,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008694,GO:0009058,GO:0009108,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663	2.5.1.129	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	M00117	R01238,R02952,R03367,R04985,R04986,R11225	RC00391,RC00814,RC03392	ko00000,ko00001,ko00002,ko01000	-	-	-	Flavoprotein
k141_5426_46	575788.VS_2770	5.38e-270	745.0	COG0773@1|root,COG0773@2|Bacteria,1MUC5@1224|Proteobacteria,1RMMT@1236|Gammaproteobacteria,1XTVH@135623|Vibrionales	135623|Vibrionales	M	Reutilizes the intact tripeptide L-alanyl-gamma-D- glutamyl-meso-diaminopimelate by linking it to UDP-N- acetylmuramate	mpl	-	6.3.2.45	ko:K02558	-	-	-	-	ko00000,ko01000	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
k141_5426_48	243277.VC_2545	3.99e-116	333.0	COG0221@1|root,COG0221@2|Bacteria,1RA2F@1224|Proteobacteria,1RPVD@1236|Gammaproteobacteria,1XV2X@135623|Vibrionales	135623|Vibrionales	C	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions	ppa	GO:0003674,GO:0003824,GO:0004427,GO:0006793,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0044237	3.6.1.1	ko:K01507	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyrophosphatase
k141_5426_49	945550.VISI1226_19309	7.2e-310	909.0	COG2911@1|root,COG2911@2|Bacteria,1MUVD@1224|Proteobacteria,1RMMF@1236|Gammaproteobacteria,1XV86@135623|Vibrionales	135623|Vibrionales	S	protein conserved in bacteria	-	-	-	ko:K09800	-	-	-	-	ko00000,ko02000	-	-	-	TamB
k141_5426_50	675814.VIC_001000	1.48e-261	733.0	COG0729@1|root,COG0729@2|Bacteria,1MUKM@1224|Proteobacteria,1RNQ3@1236|Gammaproteobacteria,1XV1N@135623|Vibrionales	135623|Vibrionales	M	COG0729 Outer membrane protein	ytfM	-	-	ko:K07278	-	-	-	-	ko00000,ko02000	1.B.33.2.4	-	-	Bac_surface_Ag,POTRA,POTRA_TamA_1
k141_5426_51	935863.AWZR01000013_gene1497	1.1e-70	221.0	COG0225@1|root,COG0225@2|Bacteria,1MVUS@1224|Proteobacteria,1RNWU@1236|Gammaproteobacteria,1X3SJ@135614|Xanthomonadales	135614|Xanthomonadales	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	-	1.8.4.11	ko:K07304	-	-	-	-	ko00000,ko01000	-	-	-	PMSR
k141_5426_52	55601.VANGNB10_cI2308	9.04e-131	380.0	2AX1N@1|root,31NZV@2|Bacteria,1RI5Q@1224|Proteobacteria,1S6GI@1236|Gammaproteobacteria,1XTQU@135623|Vibrionales	135623|Vibrionales	S	Protein of unknown function (DUF2806)	VV10722	-	-	-	-	-	-	-	-	-	-	-	DUF2806
k141_5426_53	675806.VII_001313	3.44e-100	295.0	COG0529@1|root,COG0529@2|Bacteria,1MX0D@1224|Proteobacteria,1RNWT@1236|Gammaproteobacteria,1XUJT@135623|Vibrionales	135623|Vibrionales	F	Catalyzes the synthesis of activated sulfate	cysC	GO:0003674,GO:0003824,GO:0004020,GO:0006790,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237	2.7.1.25	ko:K00860	ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120	M00176	R00509,R04928	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase
k141_5426_54	1191299.AJYX01000022_gene2880	3.84e-297	824.0	COG0471@1|root,COG0569@1|root,COG0471@2|Bacteria,COG0569@2|Bacteria,1MU0K@1224|Proteobacteria,1RMI1@1236|Gammaproteobacteria,1XTKK@135623|Vibrionales	135623|Vibrionales	P	COG0471 Di- and tricarboxylate transporters	VP0295	-	-	-	-	-	-	-	-	-	-	-	CitMHS,TrkA_C
k141_5426_55	674977.VMC_03690	1.21e-264	737.0	COG2895@1|root,COG2895@2|Bacteria,1MUD9@1224|Proteobacteria,1RME4@1236|Gammaproteobacteria,1XSCY@135623|Vibrionales	135623|Vibrionales	H	Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily	cysN	GO:0003674,GO:0003824,GO:0004779,GO:0004781,GO:0006790,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0044237,GO:0070566	2.7.7.4	ko:K00956	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R04929	RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_EFTU
k141_5426_57	345073.VC395_2673	1.76e-126	369.0	COG0007@1|root,COG0007@2|Bacteria,1MUI0@1224|Proteobacteria,1RM9V@1236|Gammaproteobacteria,1XSWE@135623|Vibrionales	135623|Vibrionales	H	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme	cysG	-	1.3.1.76,2.1.1.107,4.99.1.4	ko:K02302,ko:K02303	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03194,R03947	RC00003,RC00871,RC01012,RC01034	ko00000,ko00001,ko00002,ko01000	-	-	-	CysG_dimeriser,NAD_binding_7,Sirohm_synth_M,TP_methylase
k141_5426_58	95619.PM1_0228440	6.64e-38	134.0	COG2153@1|root,COG2153@2|Bacteria,1MZHA@1224|Proteobacteria,1S9IF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Acyltransferase	elaA	GO:0003674,GO:0003824,GO:0006464,GO:0006473,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564	-	ko:K02348	-	-	-	-	ko00000	-	-	-	Acetyltransf_10
k141_532_1	1238450.VIBNISOn1_340030	9.67e-26	106.0	COG4104@1|root,COG4104@2|Bacteria,1N8V2@1224|Proteobacteria,1SHUF@1236|Gammaproteobacteria,1XYP8@135623|Vibrionales	135623|Vibrionales	S	PAAR repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	PAAR_motif
k141_4568_1	595460.RRSWK_06267	5.64e-86	273.0	COG0260@1|root,COG0260@2|Bacteria,2IY4Q@203682|Planctomycetes	203682|Planctomycetes	E	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides	pepA	-	3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17,Peptidase_M17_N
k141_1467_1	177437.HRM2_28000	3.72e-55	182.0	COG0535@1|root,COG0535@2|Bacteria,1MUQP@1224|Proteobacteria,42M55@68525|delta/epsilon subdivisions,2WIKM@28221|Deltaproteobacteria,2MJ60@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM Radical SAM domain protein	-	-	-	ko:K22227	-	-	-	-	ko00000	-	-	-	Fer4_12,Fer4_14,Radical_SAM,SPASM
k141_1467_2	111780.Sta7437_3804	4.55e-138	429.0	COG0847@1|root,COG0847@2|Bacteria,1G1X6@1117|Cyanobacteria,3VMDU@52604|Pleurocapsales	1117|Cyanobacteria	L	Exonuclease	-	-	-	-	-	-	-	-	-	-	-	-	RNase_T
k141_1467_3	1395571.TMS3_0102685	0.000734	41.6	COG2113@1|root,COG2113@2|Bacteria,1MVIG@1224|Proteobacteria,1RRNK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	glycine, betaine	proX	-	-	ko:K02002	ko02010,map02010	M00208	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	OpuAC
k141_785_1	595494.Tola_2350	4.7e-56	184.0	COG0637@1|root,COG0637@2|Bacteria,1MX3R@1224|Proteobacteria,1RPX2@1236|Gammaproteobacteria,1Y651@135624|Aeromonadales	135624|Aeromonadales	S	Haloacid dehalogenase-like hydrolase	-	-	3.1.3.23	ko:K19270	-	-	-	-	ko00000,ko01000	-	-	-	HAD_2
k141_785_2	1410619.SRDD_41650	6.22e-197	563.0	COG1070@1|root,COG1070@2|Bacteria,1MWS5@1224|Proteobacteria,1RP2G@1236|Gammaproteobacteria,3ZZWJ@613|Serratia	1236|Gammaproteobacteria	G	Belongs to the FGGY kinase family	lyx	-	2.7.1.53	ko:K00880	ko00040,ko00053,map00040,map00053	-	R01901,R07127	RC00002,RC00017,RC00538	ko00000,ko00001,ko01000	-	-	-	FGGY_C,FGGY_N
k141_4571_1	55601.VANGNB10_cI1064	1.15e-130	382.0	COG0524@1|root,COG0524@2|Bacteria,1MUUC@1224|Proteobacteria,1RMN2@1236|Gammaproteobacteria,1XTRF@135623|Vibrionales	135623|Vibrionales	G	COG0524 Sugar kinases, ribokinase family	-	-	2.7.1.73	ko:K00892	ko00230,map00230	-	R01131,R01228	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
k141_4175_1	247633.GP2143_00842	9.96e-117	347.0	COG1216@1|root,COG1216@2|Bacteria,1QTGS@1224|Proteobacteria,1S2ND@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
k141_4175_2	1120953.AUBH01000014_gene2530	6.82e-96	293.0	COG0726@1|root,COG0726@2|Bacteria,1MX6K@1224|Proteobacteria,1RYP1@1236|Gammaproteobacteria,464GV@72275|Alteromonadaceae	1236|Gammaproteobacteria	G	Lipopolysaccharide biosynthesis protein	walW	-	-	-	-	-	-	-	-	-	-	-	-
k141_4175_3	1120953.AUBH01000014_gene2529	1.14e-158	474.0	COG0394@1|root,COG3919@1|root,COG0394@2|Bacteria,COG3919@2|Bacteria,1R94Z@1224|Proteobacteria,1RQ74@1236|Gammaproteobacteria,4666F@72275|Alteromonadaceae	1236|Gammaproteobacteria	T	ATP-grasp	-	-	-	-	-	-	-	-	-	-	-	-	CPSase_L_D2,LMWPc
k141_4175_4	1535422.ND16A_1151	3.04e-19	97.4	COG2244@1|root,COG2244@2|Bacteria,1MUMD@1224|Proteobacteria,1SYZR@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Membrane protein involved in the export of O-antigen and teichoic acid	-	-	-	ko:K03328	-	-	-	-	ko00000	2.A.66.2	-	-	Polysacc_synt_3,Polysacc_synt_C
k141_1150_2	1238450.VIBNISOn1_800045	8.34e-311	850.0	COG0493@1|root,COG0493@2|Bacteria,1MU2H@1224|Proteobacteria,1RMY7@1236|Gammaproteobacteria,1XV02@135623|Vibrionales	135623|Vibrionales	C	COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases	gltD	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	Fer4_20,Pyr_redox_2
k141_1150_3	1348635.BBJY01000002_gene3564	0.0	2560.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1MU7B@1224|Proteobacteria,1RN2W@1236|Gammaproteobacteria,1XSWZ@135623|Vibrionales	135623|Vibrionales	E	Glutamate synthase	gltB	-	1.4.1.13,1.4.1.14	ko:K00265	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
k141_1150_4	1517681.HW45_00730	0.0	914.0	COG0493@1|root,COG0493@2|Bacteria,1MU2H@1224|Proteobacteria,1RMY7@1236|Gammaproteobacteria,1XSFD@135623|Vibrionales	135623|Vibrionales	C	COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases	gltD	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	Fer4_20,Pyr_redox_2
k141_1150_5	870967.VIS19158_01514	0.0	2676.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1MU7B@1224|Proteobacteria,1RN2W@1236|Gammaproteobacteria,1XTQD@135623|Vibrionales	135623|Vibrionales	E	Glutamate synthase	gltB	-	1.4.1.13,1.4.1.14	ko:K00265	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
k141_1150_6	945543.VIBR0546_20940	5.41e-180	506.0	COG1242@1|root,COG1242@2|Bacteria,1MUYF@1224|Proteobacteria,1RP94@1236|Gammaproteobacteria,1XSN0@135623|Vibrionales	135623|Vibrionales	S	Radical_SAM C-terminal domain	yhcC	-	-	ko:K07139	-	-	-	-	ko00000	-	-	-	Radical_SAM,Radical_SAM_C
k141_1150_7	55601.VANGNB10_cI2145c	2.84e-227	647.0	COG0642@1|root,COG0745@1|root,COG2198@1|root,COG0745@2|Bacteria,COG2198@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,1SKTW@1236|Gammaproteobacteria,1XSC0@135623|Vibrionales	135623|Vibrionales	T	aerobic respiration control sensor protein	arcB	-	2.7.13.3	ko:K07648	ko02020,ko02026,map02020,map02026	M00456	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,Hpt,PAS,PAS_4,Response_reg
k141_4572_2	4529.ORUFI03G17080.1	1.91e-45	156.0	COG2110@1|root,KOG2633@2759|Eukaryota,37P9J@33090|Viridiplantae,3G82W@35493|Streptophyta,3KQYN@4447|Liliopsida,3I6PE@38820|Poales	35493|Streptophyta	BK	Macro domain	-	-	-	-	-	-	-	-	-	-	-	-	Macro
k141_1151_1	986075.CathTA2_1658	1.71e-65	210.0	COG0444@1|root,COG0444@2|Bacteria,1TP6E@1239|Firmicutes,4HA4E@91061|Bacilli	91061|Bacilli	P	Belongs to the ABC transporter superfamily	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,oligo_HPY
k141_1468_1	1122207.MUS1_11805	1.86e-87	275.0	COG1463@1|root,COG3008@1|root,COG1463@2|Bacteria,COG3008@2|Bacteria,1MU1T@1224|Proteobacteria,1RN89@1236|Gammaproteobacteria,1XIA2@135619|Oceanospirillales	135619|Oceanospirillales	Q	Paraquat-inducible protein B	pqiB	-	-	ko:K06192	-	-	-	-	ko00000	-	-	-	MlaD
k141_1468_2	768066.HELO_2454	1.67e-100	314.0	COG2995@1|root,COG2995@2|Bacteria,1MWG1@1224|Proteobacteria,1RM9Z@1236|Gammaproteobacteria,1XIA3@135619|Oceanospirillales	135619|Oceanospirillales	S	paraquat-inducible protein A	pqiA	-	-	ko:K03808	-	-	-	-	ko00000	-	-	-	PqiA
k141_4177_1	1304885.AUEY01000142_gene1066	2.66e-128	371.0	COG2022@1|root,COG2022@2|Bacteria,1N0N5@1224|Proteobacteria,42MNC@68525|delta/epsilon subdivisions,2WIUI@28221|Deltaproteobacteria,2MIPN@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S	thiG	GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.8.1.10	ko:K03149	ko00730,ko01100,map00730,map01100	-	R10247	RC03096,RC03097,RC03461	ko00000,ko00001,ko01000	-	-	-	ThiG
k141_4177_2	649639.Bcell_0761	7e-11	62.8	COG0502@1|root,COG0502@2|Bacteria,1TPEX@1239|Firmicutes,4HFID@91061|Bacilli	91061|Bacilli	C	Thiamine biosynthesis	-	-	4.1.99.19	ko:K03150	ko00730,ko01100,map00730,map01100	-	R10246	RC01434,RC03095	ko00000,ko00001,ko01000	-	-	-	BATS,Radical_SAM
k141_533_2	1122134.KB893650_gene910	2.23e-32	134.0	COG2199@1|root,COG3706@2|Bacteria,1NECV@1224|Proteobacteria,1S1ZR@1236|Gammaproteobacteria,1XHXG@135619|Oceanospirillales	135619|Oceanospirillales	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
k141_533_3	945550.VISI1226_00030	9.66e-142	402.0	COG0603@1|root,COG0603@2|Bacteria,1MU5V@1224|Proteobacteria,1RMG9@1236|Gammaproteobacteria,1XTZ0@135623|Vibrionales	135623|Vibrionales	F	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))	queC	-	6.3.4.20	ko:K06920	ko00790,ko01100,map00790,map01100	-	R09978	RC00959	ko00000,ko00001,ko01000,ko03016	-	-	-	QueC
k141_533_4	1238450.VIBNISOn1_1670009	2.95e-117	340.0	COG0602@1|root,COG0602@2|Bacteria,1MUJ2@1224|Proteobacteria,1RNQZ@1236|Gammaproteobacteria,1XUXZ@135623|Vibrionales	135623|Vibrionales	H	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds	queE	-	4.3.99.3	ko:K10026	ko00790,ko01100,map00790,map01100	-	R10002	RC02989	ko00000,ko00001,ko01000,ko03016	-	-	-	Fer4_14,Radical_SAM
k141_533_5	1280689.AUJC01000003_gene916	1.99e-60	197.0	COG0561@1|root,COG0561@2|Bacteria,1TR16@1239|Firmicutes,248MW@186801|Clostridia,36F52@31979|Clostridiaceae	186801|Clostridia	S	Hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
k141_3848_1	701176.VIBRN418_01533	6.86e-06	47.8	COG0406@1|root,COG0406@2|Bacteria,1RHAT@1224|Proteobacteria,1S69R@1236|Gammaproteobacteria,1XWM4@135623|Vibrionales	135623|Vibrionales	G	COG0406 Fructose-2,6-bisphosphatase	cobC	-	3.1.3.73	ko:K02226	ko00860,ko01100,map00860,map01100	M00122	R04594,R11173	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	His_Phos_1
k141_3848_2	1219065.VPR01S_08_01460	1.53e-74	239.0	COG2988@1|root,COG2988@2|Bacteria,1MW1T@1224|Proteobacteria,1RQPG@1236|Gammaproteobacteria,1XU9R@135623|Vibrionales	135623|Vibrionales	E	Belongs to the AspA AstE family. Succinylglutamate desuccinylase subfamily	astE	GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016787,GO:0016788,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	3.5.1.96	ko:K05526	ko00330,ko01100,map00330,map01100	-	R00411	RC00064,RC00090	ko00000,ko00001,ko01000	-	-	-	AstE_AspA
k141_3848_3	1219065.VPR01S_08_01470	2.17e-150	432.0	COG4139@1|root,COG4139@2|Bacteria,1R34H@1224|Proteobacteria,1RR7W@1236|Gammaproteobacteria,1XUHT@135623|Vibrionales	135623|Vibrionales	H	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Involved in the translocation of the substrate across the membrane	btuC	GO:0003674,GO:0003824,GO:0005215,GO:0006810,GO:0006855,GO:0008150,GO:0015238,GO:0015399,GO:0015405,GO:0015420,GO:0015889,GO:0015893,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0035461,GO:0042221,GO:0042493,GO:0042623,GO:0042626,GO:0043492,GO:0050896,GO:0051179,GO:0051180,GO:0051181,GO:0051184,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0090482	-	ko:K06073	ko02010,map02010	M00241	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.13	-	-	FecCD
k141_3848_4	1280001.BAOA01000019_gene497	1.56e-75	236.0	COG4138@1|root,COG4138@2|Bacteria,1NXS9@1224|Proteobacteria,1RRMD@1236|Gammaproteobacteria,1XTPP@135623|Vibrionales	135623|Vibrionales	P	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system	btuD	GO:0003674,GO:0003824,GO:0005215,GO:0006810,GO:0006855,GO:0008150,GO:0015238,GO:0015399,GO:0015405,GO:0015420,GO:0015889,GO:0015893,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0035461,GO:0042221,GO:0042493,GO:0042623,GO:0042626,GO:0043492,GO:0050896,GO:0051179,GO:0051180,GO:0051181,GO:0051184,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0090482	3.6.3.33	ko:K06074	ko02010,map02010	M00241	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.13	-	-	ABC_tran
k141_3848_5	945550.VISI1226_00345	2.53e-94	279.0	2EYK5@1|root,33RTU@2|Bacteria,1NQK6@1224|Proteobacteria,1SKUJ@1236|Gammaproteobacteria,1XSV5@135623|Vibrionales	135623|Vibrionales	S	Phosphoribosyl-ATP pyrophosphohydrolase	VP1313	-	-	-	-	-	-	-	-	-	-	-	PRA-PH
k141_3848_6	945550.VISI1226_00020	5.01e-61	189.0	2E73W@1|root,331NB@2|Bacteria,1N81U@1224|Proteobacteria,1SCT8@1236|Gammaproteobacteria,1XXHR@135623|Vibrionales	135623|Vibrionales	S	Protein of unknown function (DUF2750)	SO1991	-	-	-	-	-	-	-	-	-	-	-	DUF2750
k141_3848_7	1238450.VIBNISOn1_1390017	1.23e-173	485.0	COG3293@1|root,COG3293@2|Bacteria,1PHVN@1224|Proteobacteria,1TKX0@1236|Gammaproteobacteria,1Y1PA@135623|Vibrionales	135623|Vibrionales	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
k141_3848_8	575788.VS_1844	4.31e-26	103.0	COG2885@1|root,COG2885@2|Bacteria,1R8DG@1224|Proteobacteria,1SYZF@1236|Gammaproteobacteria,1XUUM@135623|Vibrionales	135623|Vibrionales	M	COG2885 Outer membrane protein and related peptidoglycan-associated (lipo)proteins	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
k141_1470_1	706587.Desti_2669	1.21e-130	383.0	COG5557@1|root,COG5557@2|Bacteria,1PFX4@1224|Proteobacteria,42NUN@68525|delta/epsilon subdivisions,2WJHN@28221|Deltaproteobacteria,2MQS4@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	PFAM Polysulphide reductase, NrfD	dsrP	-	-	ko:K00185	-	-	-	-	ko00000	5.A.3	-	-	NrfD
k141_5161_6	1128398.Curi_c24040	1.69e-273	763.0	COG0369@1|root,COG1151@2|Bacteria,1TP8X@1239|Firmicutes,247IN@186801|Clostridia,267Y7@186813|unclassified Clostridiales	186801|Clostridia	C	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O	hcp	-	1.7.99.1	ko:K05601	ko00910,map00910	-	R00143	RC02797	ko00000,ko00001,ko01000	-	-	-	Prismane
k141_5161_7	1195236.CTER_2579	1.18e-55	184.0	COG0664@1|root,COG0664@2|Bacteria,1TSP9@1239|Firmicutes,24FRD@186801|Clostridia,3WIW5@541000|Ruminococcaceae	186801|Clostridia	K	Cyclic nucleotide-binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Crp_2,cNMP_binding
k141_5161_8	926561.KB900617_gene1208	7.59e-99	291.0	COG1592@1|root,COG1592@2|Bacteria,1V1FF@1239|Firmicutes,248V2@186801|Clostridia,3WC58@53433|Halanaerobiales	186801|Clostridia	C	Ferritin-like domain	rbr	GO:0003674,GO:0003824,GO:0004601,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009636,GO:0009987,GO:0016209,GO:0016491,GO:0016684,GO:0016692,GO:0022900,GO:0042221,GO:0044237,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
k141_5161_9	883.DvMF_2481	2.26e-45	150.0	COG2033@1|root,COG2033@2|Bacteria,1RHE0@1224|Proteobacteria,42SB9@68525|delta/epsilon subdivisions,2WP2D@28221|Deltaproteobacteria,2MBEZ@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	PFAM Desulfoferrodoxin ferrous iron-binding region	dfx	-	1.15.1.2	ko:K05919	-	-	-	-	ko00000,ko01000	-	-	-	Desulfoferrod_N,Desulfoferrodox
k141_5161_10	521045.Kole_1249	1.05e-52	171.0	COG1225@1|root,COG1225@2|Bacteria,2GD74@200918|Thermotogae	200918|Thermotogae	O	AhpC/TSA family	-	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA,Nitroreductase
k141_5161_11	203119.Cthe_0245	1.57e-52	168.0	COG0640@1|root,COG0640@2|Bacteria,1VA6G@1239|Firmicutes,24JCN@186801|Clostridia,3WK18@541000|Ruminococcaceae	186801|Clostridia	K	regulatory protein, arsR	ziaR	-	-	ko:K21903	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5
k141_5161_12	1408422.JHYF01000016_gene47	1.91e-64	233.0	COG1277@1|root,COG1277@2|Bacteria,1TRJ8@1239|Firmicutes,24EMN@186801|Clostridia,36UPT@31979|Clostridiaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	-
k141_5161_13	332101.JIBU02000097_gene4099	3.89e-116	343.0	COG1131@1|root,COG1131@2|Bacteria,1TPQW@1239|Firmicutes,248F7@186801|Clostridia,36DSS@31979|Clostridiaceae	186801|Clostridia	V	ABC transporter	ytrB	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
k141_5161_14	796606.BMMGA3_08670	1.14e-41	141.0	COG1725@1|root,COG1725@2|Bacteria,1VFD0@1239|Firmicutes,4HNIT@91061|Bacilli,1ZQA5@1386|Bacillus	91061|Bacilli	K	Transcriptional regulator	ytrA	-	-	ko:K07979	-	-	-	-	ko00000,ko03000	-	-	-	GntR
k141_1161_2	1238237.CP10139811_0754	3.09e-54	184.0	COG0648@1|root,COG0648@2|Bacteria,2JFHU@204428|Chlamydiae	204428|Chlamydiae	L	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin	nfo	-	3.1.21.2	ko:K01151	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AP_endonuc_2
k141_1164_1	863239.AFIZ01000021_gene1480	2.24e-08	59.3	COG1123@1|root,COG4172@2|Bacteria,2H3HY@201174|Actinobacteria,22K9W@1653|Corynebacteriaceae	201174|Actinobacteria	P	Belongs to the ABC transporter superfamily	dppD	-	-	ko:K02031,ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
k141_1851_1	1208321.D104_01500	1.18e-87	271.0	COG0204@1|root,COG0204@2|Bacteria,1MVWG@1224|Proteobacteria,1RR21@1236|Gammaproteobacteria,1XJ5B@135619|Oceanospirillales	135619|Oceanospirillales	I	Acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
k141_1851_2	926561.KB900621_gene2825	9.89e-185	530.0	COG0415@1|root,COG0415@2|Bacteria,1UDZT@1239|Firmicutes,249FJ@186801|Clostridia,3WAHJ@53433|Halanaerobiales	186801|Clostridia	L	PFAM DNA photolyase	phr	-	4.1.99.3	ko:K01669	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_photolyase
k141_183_1	225849.swp_0984	1.41e-41	144.0	COG1309@1|root,COG1309@2|Bacteria,1RBX6@1224|Proteobacteria,1S7PJ@1236|Gammaproteobacteria,2QEIT@267890|Shewanellaceae	1236|Gammaproteobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
k141_183_2	177439.DP1072	3.91e-93	278.0	COG0655@1|root,COG0655@2|Bacteria,1RD5X@1224|Proteobacteria,42T3S@68525|delta/epsilon subdivisions,2WN8N@28221|Deltaproteobacteria,2MNBU@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Flavodoxin-like fold	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
k141_183_3	500633.CLOHIR_01547	1.55e-86	268.0	COG1032@1|root,COG1032@2|Bacteria,1TQF0@1239|Firmicutes,24A0T@186801|Clostridia,25TEV@186804|Peptostreptococcaceae	186801|Clostridia	C	Radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
k141_183_4	1121396.KB893062_gene2734	2.19e-46	152.0	2DTV6@1|root,32UW0@2|Bacteria,1NM1T@1224|Proteobacteria,42Y2A@68525|delta/epsilon subdivisions,2WT8Y@28221|Deltaproteobacteria,2MP2W@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_2440_1	177437.HRM2_45860	1.6e-19	88.6	COG0482@1|root,COG0482@2|Bacteria,1MUT1@1224|Proteobacteria,42MZR@68525|delta/epsilon subdivisions,2WK6B@28221|Deltaproteobacteria,2MIRT@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
k141_2440_2	880072.Desac_1313	3.07e-36	128.0	COG1145@1|root,COG1145@2|Bacteria,1QWP6@1224|Proteobacteria,43BU8@68525|delta/epsilon subdivisions,2X759@28221|Deltaproteobacteria,2MRTJ@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	NIL	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_4,Fer4_7,NIL
k141_2440_3	859657.RPSI07_1007	1.61e-23	90.9	COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,2VVTG@28216|Betaproteobacteria,1K9CX@119060|Burkholderiaceae	28216|Betaproteobacteria	K	Cold shock protein	cspD	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
k141_1854_1	879212.DespoDRAFT_00669	1.9e-75	243.0	COG1217@1|root,COG1217@2|Bacteria,1MV5Q@1224|Proteobacteria,42M3S@68525|delta/epsilon subdivisions,2WJVZ@28221|Deltaproteobacteria,2MIT4@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Elongation factor Tu domain 2	typA	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2
k141_5172_3	1051646.VITU9109_21799	2.4e-35	134.0	COG2207@1|root,COG2207@2|Bacteria,1N7DZ@1224|Proteobacteria,1SYZE@1236|Gammaproteobacteria,1XWDS@135623|Vibrionales	135623|Vibrionales	K	COG2207 AraC-type DNA-binding domain-containing proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
k141_5172_4	243277.VC_1419	2.22e-98	293.0	2AW6U@1|root,31N1V@2|Bacteria,1QJTI@1224|Proteobacteria,1THUT@1236|Gammaproteobacteria,1XXMM@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_5172_5	55601.VANGNB10_cII0281	5.84e-34	132.0	COG3675@1|root,COG3675@2|Bacteria,1NE77@1224|Proteobacteria,1SCTF@1236|Gammaproteobacteria,1XV9C@135623|Vibrionales	135623|Vibrionales	I	Lipase (class 3)	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_3
k141_5172_6	243277.VC_1418	1.31e-249	703.0	COG3675@1|root,COG3675@2|Bacteria,1NE77@1224|Proteobacteria,1SCTF@1236|Gammaproteobacteria,1XV9C@135623|Vibrionales	135623|Vibrionales	I	Lipase (class 3)	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_3
k141_5172_7	55601.VANGNB10_cII0280	2.03e-89	273.0	2ED8R@1|root,3375A@2|Bacteria,1NCJG@1224|Proteobacteria,1SDMR@1236|Gammaproteobacteria,1XXR5@135623|Vibrionales	135623|Vibrionales	S	Domain of unknown function (DUF4123)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4123
k141_1168_1	1187848.AJYQ01000079_gene1185	7.88e-11	62.4	COG4886@1|root,COG4886@2|Bacteria,1NF8D@1224|Proteobacteria,1SYIT@1236|Gammaproteobacteria,1XT24@135623|Vibrionales	135623|Vibrionales	S	Leucine-rich repeat (LRR) protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_1168_2	55601.VANGNB10_cII0778	1.23e-40	136.0	COG3691@1|root,COG3691@2|Bacteria,1NNR5@1224|Proteobacteria,1SHHC@1236|Gammaproteobacteria,1XYHA@135623|Vibrionales	135623|Vibrionales	S	protein conserved in bacteria	VPA0419	-	-	-	-	-	-	-	-	-	-	-	DUF406
k141_185_2	1304885.AUEY01000001_gene3296	5.84e-53	179.0	COG0170@1|root,COG0170@2|Bacteria,1NAJ2@1224|Proteobacteria	1224|Proteobacteria	I	Dolichol kinase	sec59	-	-	-	-	-	-	-	-	-	-	-	CTP_transf_1
k141_2802_1	1304885.AUEY01000039_gene1538	4.39e-103	314.0	COG0772@1|root,COG0772@2|Bacteria,1MUK3@1224|Proteobacteria,42MQT@68525|delta/epsilon subdivisions,2WIP1@28221|Deltaproteobacteria,2MJ4R@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Peptidoglycan polymerase that is essential for cell wall elongation	mrdB	-	-	ko:K05837	-	-	-	-	ko00000,ko03036	-	-	-	FTSW_RODA_SPOVE
k141_2802_2	1232437.KL662077_gene1920	1.71e-192	561.0	COG0768@1|root,COG0768@2|Bacteria,1MV8C@1224|Proteobacteria,42M1S@68525|delta/epsilon subdivisions,2WJ02@28221|Deltaproteobacteria,2MHV4@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Penicillin-binding Protein dimerisation domain	mrdA	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	iAF987.Gmet_0928	PBP_dimer,Transpeptidase
k141_2802_4	1121396.KB892924_gene644	1.8e-62	203.0	COG1792@1|root,COG1792@2|Bacteria,1N8ZS@1224|Proteobacteria,42S9I@68525|delta/epsilon subdivisions,2WNTW@28221|Deltaproteobacteria,2MJMG@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Involved in formation and maintenance of cell shape	mreC	-	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
k141_1169_1	1120973.AQXL01000122_gene190	8.81e-24	97.8	COG4608@1|root,COG4608@2|Bacteria,1V36J@1239|Firmicutes,4H9YB@91061|Bacilli	91061|Bacilli	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
k141_1169_2	266264.Rmet_1407	1.18e-19	90.5	COG1123@1|root,COG4172@2|Bacteria,1MU09@1224|Proteobacteria,2VH5T@28216|Betaproteobacteria,1K0HY@119060|Burkholderiaceae	28216|Betaproteobacteria	P	Belongs to the ABC transporter superfamily	gsiA	-	-	ko:K13892	ko02010,map02010	M00348	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.11	-	-	ABC_tran,oligo_HPY
k141_2441_1	696369.KI912183_gene2088	3.32e-155	443.0	COG1086@1|root,COG1086@2|Bacteria,1TPTC@1239|Firmicutes,247YC@186801|Clostridia,261NG@186807|Peptococcaceae	186801|Clostridia	GM	Polysaccharide biosynthesis protein	capD	-	5.1.3.2	ko:K17716	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00362	R00291	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Polysacc_syn_2C,Polysacc_synt_2
k141_1170_1	55601.VANGNB10_cI1412	6.57e-91	283.0	COG2770@1|root,COG3437@1|root,COG2770@2|Bacteria,COG3437@2|Bacteria,1MUB8@1224|Proteobacteria,1RPH3@1236|Gammaproteobacteria,1XT5R@135623|Vibrionales	135623|Vibrionales	T	COG3437 Response regulator containing a CheY-like receiver domain and an HD-GYP domain	-	-	-	ko:K07814	-	-	-	-	ko00000,ko02022	-	-	-	HD,HD_5
k141_2803_1	1348635.BBJY01000008_gene1884	1.51e-169	483.0	COG4671@1|root,COG4671@2|Bacteria,1QUFP@1224|Proteobacteria,1T1XC@1236|Gammaproteobacteria,1XTDK@135623|Vibrionales	135623|Vibrionales	S	COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_3
k141_186_1	1307761.L21SP2_3376	3.96e-203	588.0	COG0737@1|root,COG0737@2|Bacteria	2|Bacteria	F	nucleotide catabolic process	-	-	3.1.3.1,3.1.3.5	ko:K01077,ko:K01081	ko00230,ko00240,ko00730,ko00760,ko00790,ko01100,ko01110,ko02020,map00230,map00240,map00730,map00760,map00790,map01100,map01110,map02020	M00126	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02135,R02323,R02719,R03346,R04620	RC00017	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	-	-	-	5_nucleotid_C,Big_5,Exo_endo_phos,HemolysinCabind,Metallophos,Phytase-like
k141_2442_1	163908.KB235896_gene2428	2.04e-40	159.0	COG0515@1|root,COG2203@1|root,COG3899@1|root,COG0515@2|Bacteria,COG2203@2|Bacteria,COG3899@2|Bacteria	2|Bacteria	T	PFAM Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,AAA_35,GAF,GAF_2,GGDEF,Guanylate_cyc,HATPase_c,HisKA,HisKA_3,PAS_9,Pkinase,Response_reg,SpoIIE
k141_188_2	1434325.AZQN01000001_gene164	6.49e-07	58.9	COG0438@1|root,COG0438@2|Bacteria,4NI3I@976|Bacteroidetes,47MKE@768503|Cytophagia	976|Bacteroidetes	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
k141_1171_1	1121012.AUKX01000089_gene988	2.71e-60	194.0	COG0300@1|root,COG0300@2|Bacteria,4NK81@976|Bacteroidetes,1I21H@117743|Flavobacteriia	976|Bacteroidetes	S	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
k141_1171_2	1415774.U728_1001	5.01e-65	208.0	COG1073@1|root,COG1073@2|Bacteria,1U9AI@1239|Firmicutes,24B6Z@186801|Clostridia,36F9A@31979|Clostridiaceae	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Hydrolase_4
k141_1171_3	1173020.Cha6605_1442	6.31e-26	101.0	COG4994@1|root,COG4994@2|Bacteria,1G8MV@1117|Cyanobacteria	1117|Cyanobacteria	S	Domain of unknown function (DUF4440)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440
k141_1287_13	929556.Solca_0797	3.8e-64	202.0	COG5113@1|root,COG3236@2|Bacteria,4NP2J@976|Bacteroidetes,1IT1V@117747|Sphingobacteriia	976|Bacteroidetes	O	Domain of unknown function (DUF1768)	-	-	-	ko:K09935	-	-	-	-	ko00000	-	-	-	DUF1768
k141_4018_5	439235.Dalk_2649	9.21e-197	555.0	COG1104@1|root,COG1104@2|Bacteria,1MU1C@1224|Proteobacteria,42M5V@68525|delta/epsilon subdivisions,2WIR6@28221|Deltaproteobacteria,2MHW4@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine	nifS-1	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
k141_4018_6	1304885.AUEY01000058_gene2311	3.96e-82	252.0	COG0694@1|root,COG0822@1|root,COG0694@2|Bacteria,COG0822@2|Bacteria,1RD5K@1224|Proteobacteria,42MT6@68525|delta/epsilon subdivisions,2WJBU@28221|Deltaproteobacteria,2MIAE@213118|Desulfobacterales	28221|Deltaproteobacteria	C	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins	nifU	-	-	ko:K04488,ko:K13819	-	-	-	-	ko00000	-	-	-	Fer2_BFD,NifU,NifU_N
k141_1314_1	1232437.KL661976_gene4981	5.02e-71	222.0	COG1187@1|root,COG1187@2|Bacteria,1MUCE@1224|Proteobacteria,42NI7@68525|delta/epsilon subdivisions,2WNPX@28221|Deltaproteobacteria,2MJIB@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Belongs to the pseudouridine synthase RsuA family	rluB	-	5.4.99.21,5.4.99.22	ko:K06178,ko:K06182	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
k141_1314_2	1232437.KL661976_gene4980	3.53e-123	368.0	COG1364@1|root,COG1364@2|Bacteria,1MU0T@1224|Proteobacteria,42M6S@68525|delta/epsilon subdivisions,2WJU8@28221|Deltaproteobacteria,2MIPX@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate	argJ	GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.3.1.1,2.3.1.35	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259,R02282	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	ArgJ
k141_5008_1	675814.VIC_001797	7.07e-65	210.0	COG2067@1|root,COG2067@2|Bacteria,1NM5K@1224|Proteobacteria,1SKF5@1236|Gammaproteobacteria,1XSQN@135623|Vibrionales	135623|Vibrionales	I	long-chain fatty acid transport protein	fadL	-	-	ko:K06076	-	-	-	-	ko00000,ko02000	1.B.9	-	-	Toluene_X
k141_5008_2	945550.VISI1226_17375	7.4e-67	208.0	COG0394@1|root,COG0394@2|Bacteria,1RH90@1224|Proteobacteria,1S5X6@1236|Gammaproteobacteria,1XXD3@135623|Vibrionales	135623|Vibrionales	T	Belongs to the low molecular weight phosphotyrosine protein phosphatase family	-	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
k141_5008_3	1051646.VITU9109_24450	4.42e-50	159.0	2EA1K@1|root,3346W@2|Bacteria,1NBQF@1224|Proteobacteria,1SCG9@1236|Gammaproteobacteria,1XYID@135623|Vibrionales	135623|Vibrionales	S	Nitrogen fixation protein NifW	-	-	-	-	-	-	-	-	-	-	-	-	NifW
k141_5008_4	55601.VANGNB10_cI0917c	4.35e-114	330.0	COG2109@1|root,COG2109@2|Bacteria,1MUN6@1224|Proteobacteria,1RMH9@1236|Gammaproteobacteria,1XSJ7@135623|Vibrionales	135623|Vibrionales	H	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids	btuR	-	2.5.1.17	ko:K19221	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	Co_AT_N,CobA_CobO_BtuR
k141_5008_5	1348635.BBJY01000007_gene94	1.51e-116	339.0	COG0300@1|root,COG0300@2|Bacteria,1N19P@1224|Proteobacteria,1S0BR@1236|Gammaproteobacteria,1XU7Q@135623|Vibrionales	2|Bacteria	S	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short
k141_2919_1	675815.VOA_002246	1.29e-120	351.0	28HXC@1|root,2Z831@2|Bacteria,1R415@1224|Proteobacteria,1RNDD@1236|Gammaproteobacteria,1XSGV@135623|Vibrionales	135623|Vibrionales	-	-	EBIG1844	-	-	-	-	-	-	-	-	-	-	-	-
k141_2919_2	312309.VF_1755	3.2e-134	384.0	COG0284@1|root,COG0284@2|Bacteria,1MW2C@1224|Proteobacteria,1RNJR@1236|Gammaproteobacteria,1XUKK@135623|Vibrionales	135623|Vibrionales	F	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)	pyrF	GO:0003674,GO:0003824,GO:0004590,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase
k141_2919_4	1517681.HW45_23495	2.08e-28	105.0	COG3771@1|root,COG3771@2|Bacteria,1MZGX@1224|Proteobacteria,1S9X9@1236|Gammaproteobacteria,1XYIY@135623|Vibrionales	135623|Vibrionales	S	Involved in the assembly of lipopolysaccharide (LPS)	lapA	-	-	ko:K08992	-	-	-	-	ko00000	-	-	-	LapA_dom
k141_920_2	536232.CLM_2879	2.4e-16	79.0	COG0679@1|root,COG0679@2|Bacteria,1UY4N@1239|Firmicutes,24ACC@186801|Clostridia,36DT1@31979|Clostridiaceae	186801|Clostridia	S	auxin efflux carrier	-	-	-	ko:K07088	-	-	-	-	ko00000	-	-	-	Mem_trans
k141_4019_1	1121904.ARBP01000002_gene6922	4.37e-61	216.0	COG2319@1|root,COG4249@1|root,COG2319@2|Bacteria,COG4249@2|Bacteria,4NJZ8@976|Bacteroidetes,47X9Q@768503|Cytophagia	976|Bacteroidetes	S	Caspase domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C14,WD40
k141_4019_2	1121448.DGI_0591	5.19e-31	115.0	COG1830@1|root,COG1830@2|Bacteria,1MWJW@1224|Proteobacteria,42NP9@68525|delta/epsilon subdivisions,2WIP9@28221|Deltaproteobacteria,2M85K@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	Catalyzes a transaldol reaction between 6-deoxy-5- ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2- amino-3,7-dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids	aroA'	-	4.1.2.13	ko:K11645	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	DeoC
k141_5009_1	1304885.AUEY01000068_gene1401	1.54e-137	430.0	COG1643@1|root,COG1643@2|Bacteria,1MUEQ@1224|Proteobacteria,42MD4@68525|delta/epsilon subdivisions,2WJ7Z@28221|Deltaproteobacteria,2MIAK@213118|Desulfobacterales	28221|Deltaproteobacteria	L	TIGRFAM ATP-dependent helicase HrpA	hrpA	-	3.6.4.13	ko:K03578,ko:K03579	-	-	-	-	ko00000,ko01000	-	-	-	AAA_19,DEAD,DUF3418,HA2,Helicase_C,OB_NTP_bind
k141_2360_1	1348635.BBJY01000010_gene1284	2.37e-115	345.0	COG0168@1|root,COG0168@2|Bacteria,1N412@1224|Proteobacteria,1RR24@1236|Gammaproteobacteria,1XSUX@135623|Vibrionales	135623|Vibrionales	P	COG0168 Trk-type K transport systems, membrane components	ktrB	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
k141_2360_2	223926.28805891	3.79e-106	311.0	COG0569@1|root,COG0569@2|Bacteria,1N64R@1224|Proteobacteria,1SZZF@1236|Gammaproteobacteria,1XURF@135623|Vibrionales	135623|Vibrionales	P	TrkA-N domain	ktrA	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
k141_2360_3	1187848.AJYQ01000012_gene3717	4.51e-21	88.2	COG2198@1|root,COG2198@2|Bacteria,1NH5B@1224|Proteobacteria,1SGR8@1236|Gammaproteobacteria,1XYAG@135623|Vibrionales	135623|Vibrionales	T	Phosphorelay protein which receives a sensory signal from a sensor kinase and transmit it to LuxO. At low cell density, a phosphoryl group is transferred from the sensor kinase, probably on His-56 and this phosphoryl group is further transferred to LuxO	luxU	GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008218,GO:0009372,GO:0009987,GO:0023052,GO:0044237,GO:0044764,GO:0050789,GO:0050794,GO:0050896,GO:0051704,GO:0051716,GO:0065007	-	ko:K10911	ko02020,ko02024,ko05111,map02020,map02024,map05111	M00513	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Hpt
k141_2360_4	675815.VOA_000612	6.59e-111	332.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria,1XTGI@135623|Vibrionales	135623|Vibrionales	T	COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains	luxO	GO:0000156,GO:0000160,GO:0003674,GO:0003700,GO:0006355,GO:0007154,GO:0007165,GO:0008150,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0023052,GO:0031323,GO:0031326,GO:0035556,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0051716,GO:0060089,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2001141	-	ko:K10912	ko02020,ko02024,ko05111,map02020,map02024,map05111	M00513	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
k141_2920_2	1265505.ATUG01000003_gene214	2.64e-199	565.0	COG1190@1|root,COG1190@2|Bacteria,1MX1V@1224|Proteobacteria,42M90@68525|delta/epsilon subdivisions,2WJ9G@28221|Deltaproteobacteria,2MHV2@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Belongs to the class-II aminoacyl-tRNA synthetase family	lysS	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
k141_5261_1	1348635.BBJY01000012_gene1148	4.11e-234	659.0	COG0815@1|root,COG0815@2|Bacteria,1MUBU@1224|Proteobacteria,1RM8M@1236|Gammaproteobacteria,1XSXY@135623|Vibrionales	135623|Vibrionales	M	Transfers the fatty acyl group on membrane lipoproteins	lnt	GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564	-	ko:K03820	-	-	-	-	ko00000,ko01000	-	GT2	-	CN_hydrolase
k141_5261_2	701176.VIBRN418_12075	2.45e-59	188.0	COG2888@1|root,COG2888@2|Bacteria,1P9T7@1224|Proteobacteria,1SAPZ@1236|Gammaproteobacteria,1XU0U@135623|Vibrionales	135623|Vibrionales	J	Zinc-ribbon containing domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF1451
k141_5261_4	1136163.M565_ctg1P1820	4.48e-64	204.0	COG2980@1|root,COG2980@2|Bacteria,1NGPX@1224|Proteobacteria,1SGKQ@1236|Gammaproteobacteria,1Y2PX@135623|Vibrionales	135623|Vibrionales	M	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane	lptE	-	-	ko:K03643	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	LptE
k141_5261_5	1348635.BBJY01000012_gene1152	1.45e-133	390.0	COG1466@1|root,COG1466@2|Bacteria,1MWYT@1224|Proteobacteria,1RQRE@1236|Gammaproteobacteria,1XUE0@135623|Vibrionales	135623|Vibrionales	L	DNA polymerase III, delta subunit	holA	-	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delt_C,DNA_pol3_delta
k141_5261_6	1236542.BALM01000016_gene1343	3.39e-05	44.3	COG0799@1|root,COG0799@2|Bacteria,1MZEF@1224|Proteobacteria,1S8W3@1236|Gammaproteobacteria,2QC7G@267890|Shewanellaceae	1236|Gammaproteobacteria	J	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation	rsfS	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006417,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0043021,GO:0043023,GO:0044087,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:0090069,GO:0090071,GO:2000112,GO:2000113	-	ko:K09710	-	-	-	-	ko00000,ko03009	-	-	-	RsfS
k141_2361_1	298386.PBPRA1825	2.07e-26	107.0	COG3316@1|root,COG3316@2|Bacteria,1RHKZ@1224|Proteobacteria,1S7XK@1236|Gammaproteobacteria,1Y33H@135623|Vibrionales	135623|Vibrionales	L	Transposase IS66 family	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS66,LZ_Tnp_IS66,zf-IS66
k141_4728_1	1280692.AUJL01000004_gene832	4.23e-35	139.0	COG3266@1|root,COG3266@2|Bacteria,1UNJR@1239|Firmicutes,25HET@186801|Clostridia,36VAC@31979|Clostridiaceae	186801|Clostridia	S	Siphovirus ReqiPepy6 Gp37-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Collagen,Sipho_Gp37
k141_4728_2	1589749.A0A0B5A4Y7_9CAUD	1.84e-41	163.0	4QM2Z@10699|Siphoviridae	10699|Siphoviridae	S	cell adhesion	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_4728_3	767817.Desgi_4494	4.28e-56	189.0	COG4722@1|root,COG4722@2|Bacteria,1V3B1@1239|Firmicutes,24G0I@186801|Clostridia,265HD@186807|Peptococcaceae	186801|Clostridia	S	PFAM Phage tail protein	-	-	-	-	-	-	-	-	-	-	-	-	Sipho_tail
k141_4728_4	1405498.SSIM_10965	1.31e-74	283.0	COG0739@1|root,COG3953@1|root,COG5283@1|root,COG5412@1|root,COG0739@2|Bacteria,COG3953@2|Bacteria,COG5283@2|Bacteria,COG5412@2|Bacteria,1TQ28@1239|Firmicutes,4HAFE@91061|Bacilli,4GY27@90964|Staphylococcaceae	91061|Bacilli	M	Phage tail tape measure protein	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23,PhageMin_Tail,SLT
k141_4728_6	536233.CLO_0548	7.05e-31	115.0	28UBF@1|root,2ZGGV@2|Bacteria,1W48W@1239|Firmicutes,24ISP@186801|Clostridia,36IPP@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_4728_7	332101.JIBU02000023_gene4729	1.22e-56	188.0	2EPUD@1|root,33HEV@2|Bacteria,1VQ67@1239|Firmicutes,24F12@186801|Clostridia,36GH8@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_4728_9	1443122.Z958_05860	9.39e-35	122.0	2EF0N@1|root,338TS@2|Bacteria,1UBZQ@1239|Firmicutes,24RA8@186801|Clostridia,36MZZ@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_4728_10	536233.CLO_0543	1.39e-22	92.4	2ADX2@1|root,313P6@2|Bacteria,1UHF9@1239|Firmicutes,24RWS@186801|Clostridia,36MW3@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_4728_11	1443122.Z958_05850	1.63e-29	108.0	2BETZ@1|root,30HCB@2|Bacteria,1UHFM@1239|Firmicutes,24RXA@186801|Clostridia,36NI1@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_4728_13	1415774.U728_828	4.85e-180	509.0	28PY7@1|root,2ZCHY@2|Bacteria,1V2M7@1239|Firmicutes,24CTQ@186801|Clostridia,36H3Q@31979|Clostridiaceae	186801|Clostridia	S	Phage major capsid protein E	-	-	-	-	-	-	-	-	-	-	-	-	Phage_cap_E
k141_4728_14	748727.CLJU_c31320	9.46e-20	84.7	2BAU4@1|root,3249E@2|Bacteria,1UQKG@1239|Firmicutes,24U9Y@186801|Clostridia,36MJG@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_4728_15	1121342.AUCO01000012_gene1696	6.54e-26	107.0	2DPCU@1|root,331IS@2|Bacteria,1UPSP@1239|Firmicutes,25HNC@186801|Clostridia,36VBI@31979|Clostridiaceae	186801|Clostridia	S	Phage minor structural protein GP20	-	-	-	-	-	-	-	-	-	-	-	-	Phage_GP20
k141_4728_19	1121342.AUCO01000012_gene1699	3.42e-84	263.0	29XPS@1|root,30JFE@2|Bacteria,1UKZ4@1239|Firmicutes,24BJ4@186801|Clostridia,36GV7@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_4728_20	1121342.AUCO01000012_gene1700	1.51e-180	524.0	2EQUX@1|root,33IEQ@2|Bacteria,1W342@1239|Firmicutes,24991@186801|Clostridia,36G9P@31979|Clostridiaceae	186801|Clostridia	S	Phage portal protein, SPP1 Gp6-like	-	-	-	-	-	-	-	-	-	-	-	-	Phage_prot_Gp6
k141_4728_21	756499.Desde_1076	4.47e-218	613.0	COG1783@1|root,COG1783@2|Bacteria,1TT2C@1239|Firmicutes,24A7T@186801|Clostridia,261RB@186807|Peptococcaceae	186801|Clostridia	S	TIGRFAM Phage terminase, large subunit, PBSX	-	-	-	-	-	-	-	-	-	-	-	-	Terminase_6,Terminase_6C
k141_4728_22	1567015.A0A0A7S1A8_9VIRU	7.66e-79	253.0	4QB6U@10239|Viruses	10239|Viruses	S	Terminase small subunit	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_4728_23	318464.IO99_13795	9.73e-22	94.7	COG1595@1|root,COG1595@2|Bacteria,1V2TE@1239|Firmicutes,24GMM@186801|Clostridia,36ISW@31979|Clostridiaceae	186801|Clostridia	K	DNA-templated transcription, initiation	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_4728_24	546269.HMPREF0389_01237	8.62e-36	128.0	COG0629@1|root,COG0629@2|Bacteria,1V3WT@1239|Firmicutes,24HF9@186801|Clostridia,25RHZ@186804|Peptostreptococcaceae	186801|Clostridia	L	Single-strand binding protein family	ssb	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
k141_4728_29	1391647.AVSV01000022_gene2538	1.9e-16	73.2	2BB9Y@1|root,324SP@2|Bacteria,1UQZ4@1239|Firmicutes,24VBZ@186801|Clostridia,36PCV@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_4728_35	931626.Awo_c35220	8.15e-23	103.0	COG3935@1|root,COG3935@2|Bacteria,1VAP8@1239|Firmicutes	1239|Firmicutes	L	DnaD domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_4728_36	1280706.AUJE01000003_gene2279	4.86e-56	188.0	COG3723@1|root,COG3723@2|Bacteria,1UNDF@1239|Firmicutes,4H38J@909932|Negativicutes	909932|Negativicutes	L	Recombinase, phage RecT family	recT	-	-	ko:K07455	-	-	-	-	ko00000,ko03400	-	-	-	RecT
k141_4728_41	1089548.KI783301_gene2641	3.01e-13	70.5	COG1396@1|root,COG1396@2|Bacteria,1VK84@1239|Firmicutes,4HR82@91061|Bacilli	91061|Bacilli	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
k141_4728_42	485916.Dtox_2431	7.74e-07	54.3	COG1396@1|root,COG1396@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19,HTH_3
k141_4728_43	696281.Desru_1066	8.45e-34	123.0	COG2856@1|root,COG2856@2|Bacteria,1V4N6@1239|Firmicutes,24JDG@186801|Clostridia,262CF@186807|Peptococcaceae	186801|Clostridia	E	Pfam:DUF955	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M78
k141_4728_44	556268.OFAG_02316	5.01e-62	228.0	COG0326@1|root,COG0326@2|Bacteria,1RJYD@1224|Proteobacteria	1224|Proteobacteria	L	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_3
k141_4728_45	1217713.F993_01554	2.95e-136	402.0	COG0863@1|root,COG0863@2|Bacteria,1RI4J@1224|Proteobacteria,1SGZ6@1236|Gammaproteobacteria,3NTEP@468|Moraxellaceae	1236|Gammaproteobacteria	L	Belongs to the N(4) N(6)-methyltransferase family	-	-	2.1.1.113	ko:K00590	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	N6_N4_Mtase
k141_4728_49	1123252.ATZF01000014_gene4248	1.22e-15	74.7	2E3YM@1|root,32YVJ@2|Bacteria,1VGJD@1239|Firmicutes,4HQK0@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	SmpA_OmlA
k141_3291_10	55601.VANGNB10_cI0223c	1.6e-196	551.0	COG1162@1|root,COG1162@2|Bacteria,1MUEF@1224|Proteobacteria,1RMMB@1236|Gammaproteobacteria,1XTBR@135623|Vibrionales	135623|Vibrionales	S	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit	rsgA	-	3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100	-	R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009	-	-	-	RsgA_GTPase
k141_5289_1	1504672.669783588	3.53e-38	153.0	COG2931@1|root,COG3210@1|root,COG4625@1|root,COG2931@2|Bacteria,COG3210@2|Bacteria,COG4625@2|Bacteria,1MU7T@1224|Proteobacteria	1224|Proteobacteria	Q	COG2931, RTX toxins and related Ca2 -binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	DUF4347,DUF5122,HemolysinCabind,Lactonase,Laminin_G_3,Peptidase_M10_C,W_rich_C
k141_2628_1	1137799.GZ78_16455	2.29e-80	252.0	COG3977@1|root,COG3977@2|Bacteria,1MVRW@1224|Proteobacteria,1RNK1@1236|Gammaproteobacteria,1XHID@135619|Oceanospirillales	135619|Oceanospirillales	E	catalyzes transamination of alanine, valine, and 2-aminobutyrate with their respective 2-keto acids	avtA	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
k141_2628_2	644282.Deba_1459	6.61e-29	119.0	COG4191@1|root,COG4191@2|Bacteria,1R02T@1224|Proteobacteria,43CPU@68525|delta/epsilon subdivisions,2X7X1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	PFAM histidine kinase, HAMP region domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF3365
k141_2628_3	1121441.AUCX01000028_gene353	3.04e-12	66.2	COG0746@1|root,COG0746@2|Bacteria,1RKCH@1224|Proteobacteria,42T8X@68525|delta/epsilon subdivisions,2WP3Q@28221|Deltaproteobacteria,2MB8C@213115|Desulfovibrionales	28221|Deltaproteobacteria	H	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor	mobA	-	2.7.7.77	ko:K03752	ko00790,ko01100,map00790,map01100	-	R11581	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
k141_5040_2	867900.Celly_1458	0.0007	48.9	COG5492@1|root,COG5492@2|Bacteria	2|Bacteria	N	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	Flg_new,LRR_5
k141_5130_11	55601.VANGNB10_cII0693	0.0	946.0	COG1289@1|root,COG1289@2|Bacteria,1MWR1@1224|Proteobacteria,1RNIJ@1236|Gammaproteobacteria,1XTGG@135623|Vibrionales	135623|Vibrionales	S	membrane	yccS	-	-	-	-	-	-	-	-	-	-	-	FUSC-like,FUSC_2
k141_5130_12	55601.VANGNB10_cII0692c	0.0	899.0	COG0210@1|root,COG0210@2|Bacteria,1MVWI@1224|Proteobacteria,1RN1N@1236|Gammaproteobacteria,1XTAF@135623|Vibrionales	135623|Vibrionales	L	COG0210 Superfamily I DNA and RNA helicases	helD	-	3.6.4.12	ko:K03658	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	Helicase_IV_N,UvrD-helicase,UvrD_C
k141_5130_13	29495.EA26_10930	1.56e-85	254.0	COG1803@1|root,COG1803@2|Bacteria,1RD3D@1224|Proteobacteria,1S3XN@1236|Gammaproteobacteria,1XV9M@135623|Vibrionales	135623|Vibrionales	G	Methylglyoxal synthase	mgsA	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0008150,GO:0008152,GO:0008929,GO:0009058,GO:0009438,GO:0009987,GO:0016829,GO:0016835,GO:0016838,GO:0019242,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0071704,GO:1901576	4.2.3.3	ko:K01734	ko00640,ko01120,map00640,map01120	-	R01016	RC00424	ko00000,ko00001,ko01000	-	-	-	MGS
k141_5130_14	1348635.BBJY01000001_gene2443	2.97e-62	194.0	COG0071@1|root,COG0071@2|Bacteria,1N7C7@1224|Proteobacteria,1S607@1236|Gammaproteobacteria,1XYRW@135623|Vibrionales	135623|Vibrionales	O	Hsp20/alpha crystallin family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
k141_5130_15	243277.VC_A0699	1.72e-234	652.0	COG0448@1|root,COG0448@2|Bacteria,1MVTC@1224|Proteobacteria,1RP04@1236|Gammaproteobacteria,1XTGB@135623|Vibrionales	135623|Vibrionales	H	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans	glgC2	GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0008878,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016772,GO:0016779,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0055114,GO:0070566,GO:0071704,GO:1901576	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
k141_5130_16	62977.ACIAD3594	9.56e-29	125.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,3NJ45@468|Moraxellaceae	1236|Gammaproteobacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	5TM-5TMR_LYT,CHASE8,EAL,GGDEF,HAMP,PAS,PAS_3,PAS_4,PAS_9
k141_5130_17	1219065.VPR01S_06_00720	2.57e-66	211.0	2EVF3@1|root,33NVI@2|Bacteria,1NPYI@1224|Proteobacteria,1SV5C@1236|Gammaproteobacteria,1XW0P@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	SH3_3
k141_5130_18	573.JG24_24650	2.16e-10	63.9	COG2731@1|root,COG2731@2|Bacteria,1RBKM@1224|Proteobacteria,1S4YJ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	Domain of unknown function (DUF386)	yiaL	-	-	-	-	-	-	-	-	-	-	-	DUF386
k141_5130_19	675812.VHA_001653	1.99e-83	253.0	COG1280@1|root,COG1280@2|Bacteria,1Q4CV@1224|Proteobacteria,1RQV8@1236|Gammaproteobacteria,1XT0S@135623|Vibrionales	135623|Vibrionales	E	LysE type translocator	-	-	-	-	-	-	-	-	-	-	-	-	LysE
k141_5130_20	1515746.HR45_18390	3.6e-176	508.0	COG1538@1|root,COG1538@2|Bacteria,1MUA8@1224|Proteobacteria,1RN0I@1236|Gammaproteobacteria,2QENS@267890|Shewanellaceae	1236|Gammaproteobacteria	MU	Outer membrane efflux protein	Z012_07725	-	-	-	-	-	-	-	-	-	-	-	OEP
k141_5130_21	1515746.HR45_18395	0.0	926.0	COG0577@1|root,COG1136@1|root,COG0577@2|Bacteria,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,1RNUJ@1236|Gammaproteobacteria,2Q9X9@267890|Shewanellaceae	1236|Gammaproteobacteria	P	Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides	macB	-	-	ko:K02003,ko:K05685	ko02010,map02010	M00258,M00709	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1,3.A.1.122.1,3.A.1.122.12	-	-	ABC_tran,FtsX,MacB_PCD
k141_5130_22	1232683.ADIMK_1291	3.75e-149	435.0	COG0845@1|root,COG0845@2|Bacteria,1MU8D@1224|Proteobacteria,1RN0E@1236|Gammaproteobacteria,466RG@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	macA	-	-	ko:K02005,ko:K13888	-	M00709	-	-	ko00000,ko00002,ko02000	8.A.1	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
k141_5130_24	377629.TERTU_1074	1.33e-278	776.0	COG2985@1|root,COG2985@2|Bacteria,1MUVM@1224|Proteobacteria,1RQY2@1236|Gammaproteobacteria,2PP7K@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	P	Predicted Permease Membrane Region	yidE	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K07085	-	-	-	-	ko00000	2.A.81	-	-	Asp-Al_Ex,TrkA_C
k141_5130_25	358220.C380_11860	1.01e-57	191.0	COG0725@1|root,COG0725@2|Bacteria,1MVNA@1224|Proteobacteria,2VJEC@28216|Betaproteobacteria,4AC9G@80864|Comamonadaceae	28216|Betaproteobacteria	P	TIGRFAM molybdenum ABC transporter, periplasmic molybdate-binding protein	modA	-	-	ko:K02020	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	-	SBP_bac_11
k141_5130_26	595494.Tola_2350	7.71e-57	187.0	COG0637@1|root,COG0637@2|Bacteria,1MX3R@1224|Proteobacteria,1RPX2@1236|Gammaproteobacteria,1Y651@135624|Aeromonadales	135624|Aeromonadales	S	Haloacid dehalogenase-like hydrolase	-	-	3.1.3.23	ko:K19270	-	-	-	-	ko00000,ko01000	-	-	-	HAD_2
k141_5130_27	643473.KB235930_gene2427	6.57e-80	277.0	COG5001@1|root,COG5001@2|Bacteria	2|Bacteria	T	cyclic-guanylate-specific phosphodiesterase activity	-	-	-	-	-	-	-	-	-	-	-	-	CBS,EAL,GAF,GGDEF,PAS_3,Response_reg
k141_5130_28	223926.28806790	2.2e-63	195.0	COG3324@1|root,COG3324@2|Bacteria,1N0AD@1224|Proteobacteria,1S8YM@1236|Gammaproteobacteria,1XY2Z@135623|Vibrionales	135623|Vibrionales	S	Glyoxalase-like domain	-	-	-	ko:K06996	-	-	-	-	ko00000	-	-	-	Glyoxalase
k141_5130_29	717774.Marme_0376	7.86e-65	205.0	29FA5@1|root,3027T@2|Bacteria,1REEQ@1224|Proteobacteria,1S4SV@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_5130_30	55601.VANGNB10_cII0529c	3.48e-78	241.0	COG2813@1|root,COG2813@2|Bacteria,1QV9D@1224|Proteobacteria,1T2AT@1236|Gammaproteobacteria,1XWFG@135623|Vibrionales	135623|Vibrionales	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
k141_5130_31	675814.VIC_002439	5.6e-52	167.0	COG1186@1|root,COG1186@2|Bacteria,1RH75@1224|Proteobacteria,1S5YQ@1236|Gammaproteobacteria,1XXE0@135623|Vibrionales	135623|Vibrionales	J	COG1186 Protein chain release factor B	yaeJ	-	-	ko:K15034	-	-	-	-	ko00000,ko03012	-	-	-	RF-1
k141_5130_32	55601.VANGNB10_cI0962c	7.01e-82	244.0	COG4628@1|root,COG4628@2|Bacteria,1N7DG@1224|Proteobacteria,1S2VZ@1236|Gammaproteobacteria,1XX0U@135623|Vibrionales	135623|Vibrionales	S	DNA-binding protein VF530	-	-	-	-	-	-	-	-	-	-	-	-	VF530
k141_5130_33	1116375.VEJY3_21491	3.19e-237	657.0	COG1979@1|root,COG1979@2|Bacteria,1QUBJ@1224|Proteobacteria,1RP7C@1236|Gammaproteobacteria,1XZTQ@135623|Vibrionales	135623|Vibrionales	C	Iron-containing alcohol dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Fe-ADH
k141_5130_34	1268072.PSAB_03885	1.46e-17	91.7	COG2206@1|root,COG2206@2|Bacteria,1TR95@1239|Firmicutes,4HDYK@91061|Bacilli,26RVZ@186822|Paenibacillaceae	91061|Bacilli	T	phosphohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HD,HD_5
k141_5130_36	907348.TresaDRAFT_2417	6.2e-142	417.0	COG0412@1|root,COG0412@2|Bacteria,2J8TN@203691|Spirochaetes	203691|Spirochaetes	Q	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_5130_38	1410670.JHXF01000005_gene1032	1.66e-17	82.0	COG1670@1|root,COG1670@2|Bacteria,1UXCB@1239|Firmicutes,2599J@186801|Clostridia,3WPSG@541000|Ruminococcaceae	186801|Clostridia	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
k141_5130_39	1096546.WYO_4720	7.57e-42	142.0	COG1733@1|root,COG1733@2|Bacteria,1MZ6G@1224|Proteobacteria,2UCP4@28211|Alphaproteobacteria,1JVSH@119045|Methylobacteriaceae	28211|Alphaproteobacteria	K	HxlR-like helix-turn-helix	yybR	-	-	-	-	-	-	-	-	-	-	-	HxlR
k141_5130_40	754436.JCM19237_2424	1.81e-98	292.0	COG0778@1|root,COG0778@2|Bacteria,1N95W@1224|Proteobacteria,1RSDH@1236|Gammaproteobacteria,1XVNT@135623|Vibrionales	135623|Vibrionales	C	Nitroreductase family	-	-	1.5.1.34	ko:K10679	ko00633,ko01120,map00633,map01120	-	R08014,R08017,R08042	RC00250	ko00000,ko00001,ko01000	-	-	-	Nitroreductase
k141_5130_41	243277.VC_1388	5.22e-169	480.0	COG0095@1|root,COG0095@2|Bacteria,1N1T8@1224|Proteobacteria,1RMGI@1236|Gammaproteobacteria,1XW3C@135623|Vibrionales	135623|Vibrionales	H	Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes	lplA	GO:0003674,GO:0003824,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009987,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0016874,GO:0016879,GO:0016979,GO:0018130,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:0140096,GO:1901360,GO:1901362,GO:1901576	6.3.1.20	ko:K03800	ko00785,ko01100,map00785,map01100	-	R07770,R07771,R11143	RC00043,RC00070,RC00090,RC00992,RC02896	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB,Lip_prot_lig_C
k141_5130_42	1288826.MSNKSG1_05853	8.97e-22	92.0	COG1585@1|root,COG1585@2|Bacteria,1NQ8Q@1224|Proteobacteria,1SPG6@1236|Gammaproteobacteria	1236|Gammaproteobacteria	OU	NfeD-like C-terminal, partner-binding	-	-	-	ko:K07340	-	-	-	-	ko00000	-	-	-	NfeD
k141_5130_43	1288826.MSNKSG1_05848	5.07e-98	298.0	COG0330@1|root,COG0330@2|Bacteria,1MUM8@1224|Proteobacteria,1RNW8@1236|Gammaproteobacteria,465XW@72275|Alteromonadaceae	1236|Gammaproteobacteria	O	COG0330 Membrane protease subunits, stomatin prohibitin homologs	qmcA	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Band_7,Band_7_C
k141_2762_1	1095750.HMPREF9970_1563	4.17e-101	312.0	COG3395@1|root,COG3395@2|Bacteria,1W75B@1239|Firmicutes,25M8U@186801|Clostridia,1HWE5@1164882|Lachnoanaerobaculum	186801|Clostridia	S	Putative nucleotide-binding of sugar-metabolising enzyme	-	-	-	-	-	-	-	-	-	-	-	-	DUF1357_C,DUF1537
k141_2762_2	1121342.AUCO01000004_gene589	6.76e-45	154.0	COG0149@1|root,COG0149@2|Bacteria,1UYUE@1239|Firmicutes,248TQ@186801|Clostridia,36RTG@31979|Clostridiaceae	186801|Clostridia	G	Triosephosphate isomerase	-	-	5.3.1.1,5.3.1.33	ko:K01803,ko:K21910	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
k141_4512_1	1121405.dsmv_1003	1.14e-70	236.0	COG0204@1|root,COG1647@1|root,COG0204@2|Bacteria,COG1647@2|Bacteria,1MVZP@1224|Proteobacteria,42NBK@68525|delta/epsilon subdivisions,2WIUP@28221|Deltaproteobacteria,2MHMP@213118|Desulfobacterales	28221|Deltaproteobacteria	I	Phosphate acyltransferases	-	-	3.1.1.1	ko:K03928	-	-	-	-	ko00000,ko01000	-	-	-	Acyltransferase,Hydrolase_4
k141_2763_1	1429851.X548_07245	5.25e-80	269.0	COG1061@1|root,COG1061@2|Bacteria,1QCQA@1224|Proteobacteria	1224|Proteobacteria	L	Type III restriction protein res subunit	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,ResIII
k141_3513_1	261292.Nit79A3_3146	1.66e-71	247.0	COG0463@1|root,COG1807@1|root,COG2246@1|root,COG0463@2|Bacteria,COG1807@2|Bacteria,COG2246@2|Bacteria,1P6JE@1224|Proteobacteria,2VN72@28216|Betaproteobacteria,371MM@32003|Nitrosomonadales	28216|Betaproteobacteria	M	PFAM Glycosyl transferase, family 2	-	-	2.4.1.83	ko:K00721,ko:K00786	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2,GtrA,PMT_2
k141_3514_1	485916.Dtox_3797	6.12e-21	84.7	2EHUE@1|root,33BK1@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_2764_1	177439.DP1926	3.45e-82	277.0	COG2984@1|root,COG4191@1|root,COG4753@1|root,COG2984@2|Bacteria,COG4191@2|Bacteria,COG4753@2|Bacteria,1RCM9@1224|Proteobacteria,42MC4@68525|delta/epsilon subdivisions,2WIZU@28221|Deltaproteobacteria,2MHWA@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	ABC_sub_bind,GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_8,PAS_9,Response_reg
k141_477_2	1304885.AUEY01000020_gene3501	8.09e-55	174.0	COG0720@1|root,COG0720@2|Bacteria,1RI4P@1224|Proteobacteria,42TJ5@68525|delta/epsilon subdivisions,2WQ2Z@28221|Deltaproteobacteria,2MJT6@213118|Desulfobacterales	28221|Deltaproteobacteria	H	PFAM 6-pyruvoyl tetrahydropterin synthase	queD	-	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	PTPS
k141_477_3	1167006.UWK_02311	3.85e-117	351.0	COG0484@1|root,COG0484@2|Bacteria,1MVMS@1224|Proteobacteria,42KZM@68525|delta/epsilon subdivisions,2WJGP@28221|Deltaproteobacteria,2MIAD@213118|Desulfobacterales	28221|Deltaproteobacteria	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
k141_477_4	933262.AXAM01000041_gene1891	4.46e-21	90.5	COG0500@1|root,COG2226@2|Bacteria,1MX8I@1224|Proteobacteria,42P2Z@68525|delta/epsilon subdivisions,2WNJ6@28221|Deltaproteobacteria,2MJ9N@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2)	ubiE	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
k141_478_1	526222.Desal_0459	3.27e-43	145.0	COG0716@1|root,COG0716@2|Bacteria,1MYWV@1224|Proteobacteria,42T4N@68525|delta/epsilon subdivisions,2WPT3@28221|Deltaproteobacteria,2MC7J@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	FMN binding	-	-	-	-	-	-	-	-	-	-	-	-	Flavodoxin_5
k141_478_2	525903.Taci_1260	1.73e-34	132.0	COG0733@1|root,COG0733@2|Bacteria,3T9W5@508458|Synergistetes	508458|Synergistetes	P	Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family	-	-	-	ko:K03308	-	-	-	-	ko00000	2.A.22.4,2.A.22.5	-	-	SNF
k141_3516_1	498211.CJA_2520	2.45e-151	487.0	COG1022@1|root,COG5184@1|root,COG5276@1|root,COG1022@2|Bacteria,COG5184@2|Bacteria,COG5276@2|Bacteria,1PG4J@1224|Proteobacteria,1RWXR@1236|Gammaproteobacteria,1FIEH@10|Cellvibrio	1236|Gammaproteobacteria	DZ	Regulator of chromosome condensation (RCC1) repeat	-	-	-	-	-	-	-	-	-	-	-	-	RCC1
k141_3517_1	439235.Dalk_0594	4.04e-54	183.0	COG4591@1|root,COG4591@2|Bacteria,1R4Q2@1224|Proteobacteria,42N3Y@68525|delta/epsilon subdivisions,2WJFS@28221|Deltaproteobacteria,2MJEA@213118|Desulfobacterales	28221|Deltaproteobacteria	M	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
k141_2765_1	1547437.LL06_25595	1.22e-14	87.8	COG2304@1|root,COG2911@1|root,COG2931@1|root,COG3210@1|root,COG4733@1|root,COG4932@1|root,COG2304@2|Bacteria,COG2911@2|Bacteria,COG2931@2|Bacteria,COG3210@2|Bacteria,COG4733@2|Bacteria,COG4932@2|Bacteria,1MU7T@1224|Proteobacteria,2UGU2@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	COG2931, RTX toxins and related Ca2 -binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	DUF4082,DUF4347,HemolysinCabind
k141_479_1	243277.VC_1629	4.3e-164	492.0	COG0577@1|root,COG0577@2|Bacteria,1MVCT@1224|Proteobacteria,1RNP1@1236|Gammaproteobacteria,1XUDJ@135623|Vibrionales	135623|Vibrionales	V	ABC-type antimicrobial peptide transport system, permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
k141_3519_1	406818.XBJ1_3055	1.41e-156	455.0	COG3385@1|root,COG3385@2|Bacteria,1RBZF@1224|Proteobacteria,1S381@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
k141_2427_2	545243.BAEV01000088_gene2299	3.68e-45	157.0	COG1595@1|root,COG1595@2|Bacteria,1TP55@1239|Firmicutes,249VX@186801|Clostridia,36ETQ@31979|Clostridiaceae	186801|Clostridia	K	Belongs to the sigma-70 factor family	sigH	-	-	ko:K03091	-	-	-	-	ko00000,ko03021	-	-	-	GerE,Sigma70_r2,Sigma70_r4_2
k141_2427_3	273068.TTE2312	6.61e-39	137.0	COG3688@1|root,COG3688@2|Bacteria,1V9XR@1239|Firmicutes,24MPI@186801|Clostridia,42GDZ@68295|Thermoanaerobacterales	186801|Clostridia	S	YacP-like NYN domain	-	-	-	ko:K06962	-	-	-	-	ko00000	-	-	-	NYN_YacP
k141_2427_4	445973.CLOBAR_00073	1.91e-91	276.0	COG0566@1|root,COG0566@2|Bacteria,1TP9G@1239|Firmicutes,247SC@186801|Clostridia,25QG5@186804|Peptostreptococcaceae	186801|Clostridia	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	yacO	-	2.1.1.185	ko:K03218	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SpoU_methylase,SpoU_sub_bind
k141_2427_5	500633.CLOHIR_01559	1.04e-128	371.0	COG1351@1|root,COG1351@2|Bacteria,1TRAA@1239|Firmicutes,249DJ@186801|Clostridia,25QWX@186804|Peptostreptococcaceae	186801|Clostridia	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant	thyX	-	2.1.1.148	ko:K03465	ko00240,ko00670,ko01100,map00240,map00670,map01100	-	R06613	RC00022,RC00332	ko00000,ko00001,ko01000	-	-	-	Thy1
k141_2427_6	318464.IO99_16490	2.61e-38	133.0	COG1939@1|root,COG1939@2|Bacteria,1VA5V@1239|Firmicutes,24MR1@186801|Clostridia,36JIS@31979|Clostridiaceae	186801|Clostridia	J	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)	mrnC	-	-	ko:K11145	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Ribonuclease_3
k141_2427_7	445973.CLOBAR_00070	9.41e-226	635.0	COG0215@1|root,COG0215@2|Bacteria,1TP9D@1239|Firmicutes,247KS@186801|Clostridia,25QJ0@186804|Peptostreptococcaceae	186801|Clostridia	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	-	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e,tRNA-synt_1g
k141_2427_8	536232.CLM_0256	1.08e-74	229.0	COG1045@1|root,COG1045@2|Bacteria,1TR42@1239|Firmicutes,249SF@186801|Clostridia,36EH9@31979|Clostridiaceae	186801|Clostridia	E	Serine acetyltransferase	cysE	-	2.3.1.30	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	M00021	R00586	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,SATase_N
k141_2427_9	1122128.AUEE01000004_gene478	1.99e-118	350.0	COG0031@1|root,COG0031@2|Bacteria,1TP30@1239|Firmicutes,4HAMU@91061|Bacilli,4GX3M@90964|Staphylococcaceae	91061|Bacilli	E	Belongs to the cysteine synthase cystathionine beta- synthase family	cysK	GO:0000096,GO:0000097,GO:0000098,GO:0003674,GO:0003824,GO:0004122,GO:0004124,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006555,GO:0006563,GO:0006790,GO:0006807,GO:0008134,GO:0008144,GO:0008150,GO:0008152,GO:0008284,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009066,GO:0009068,GO:0009069,GO:0009070,GO:0009087,GO:0009987,GO:0016043,GO:0016053,GO:0016054,GO:0016740,GO:0016765,GO:0016829,GO:0016835,GO:0016836,GO:0016846,GO:0019344,GO:0019752,GO:0019842,GO:0022607,GO:0030170,GO:0032991,GO:0032993,GO:0036094,GO:0042127,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043388,GO:0043436,GO:0043933,GO:0044085,GO:0044093,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044272,GO:0044273,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046395,GO:0046983,GO:0048037,GO:0048518,GO:0048522,GO:0050662,GO:0050789,GO:0050794,GO:0051098,GO:0051099,GO:0051101,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0051291,GO:0065003,GO:0065007,GO:0065009,GO:0070279,GO:0071704,GO:0071840,GO:0080146,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607,GO:1904796,GO:1904798,GO:2000677,GO:2000679	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
k141_2427_10	1292035.H476_2227	5.67e-55	191.0	COG0628@1|root,COG0628@2|Bacteria,1TQ84@1239|Firmicutes,248FS@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
k141_2427_11	1292035.H476_0197	8.16e-272	753.0	COG0008@1|root,COG0008@2|Bacteria,1TPJC@1239|Firmicutes,2482P@186801|Clostridia,25QPF@186804|Peptostreptococcaceae	186801|Clostridia	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17,6.1.1.24	ko:K01885,ko:K09698	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R03651,R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
k141_2427_12	1384057.CD33_16945	2.08e-150	442.0	COG1012@1|root,COG1012@2|Bacteria,1TP4S@1239|Firmicutes,4HB97@91061|Bacilli,3IVXB@400634|Lysinibacillus	91061|Bacilli	C	Belongs to the aldehyde dehydrogenase family	aldH	-	1.2.1.3	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
k141_2427_14	1163745.HCD_04745	2.22e-35	150.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42QR6@68525|delta/epsilon subdivisions,2YNXQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	NT	chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal,dCache_1
k141_2427_15	351627.Csac_0803	3.92e-41	163.0	COG0442@1|root,COG0442@2|Bacteria,1TRBV@1239|Firmicutes,249PY@186801|Clostridia,42FHT@68295|Thermoanaerobacterales	186801|Clostridia	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS	proS	-	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_edit
k141_2427_16	1121324.CLIT_24c00940	1.75e-280	774.0	COG0442@1|root,COG0442@2|Bacteria,1TRBV@1239|Firmicutes,249PY@186801|Clostridia,25S74@186804|Peptostreptococcaceae	186801|Clostridia	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro)	proS	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,ProRS-C_1,tRNA-synt_2b
k141_2427_17	1307761.L21SP2_3000	7.91e-49	160.0	COG0735@1|root,COG0735@2|Bacteria,2J8AC@203691|Spirochaetes	203691|Spirochaetes	P	Belongs to the Fur family	fur	-	-	ko:K09825	-	-	-	-	ko00000,ko03000	-	-	-	FUR
k141_2427_18	545697.HMPREF0216_00705	5.57e-73	223.0	COG0245@1|root,COG0245@2|Bacteria,1V3P0@1239|Firmicutes,24HCM@186801|Clostridia,36HZE@31979|Clostridiaceae	186801|Clostridia	I	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)	ispF	-	2.7.7.60,4.6.1.12	ko:K01770,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633,R05637	RC00002,RC01440	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD,YgbB
k141_2427_19	1301100.HG529433_gene6512	9.92e-90	271.0	COG1211@1|root,COG1211@2|Bacteria,1V3M7@1239|Firmicutes,248E6@186801|Clostridia,36EIP@31979|Clostridiaceae	186801|Clostridia	I	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)	ispD	-	2.7.7.60	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS20335	IspD
k141_2427_20	1294142.CINTURNW_2060	5.99e-61	195.0	COG0344@1|root,COG0344@2|Bacteria,1VA3J@1239|Firmicutes,24JA2@186801|Clostridia,36IPV@31979|Clostridiaceae	186801|Clostridia	I	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP	plsY	-	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	G3P_acyltransf
k141_2427_21	1121324.CLIT_24c01000	4.91e-149	432.0	COG4956@1|root,COG4956@2|Bacteria,1TP0P@1239|Firmicutes,248F4@186801|Clostridia,25QEQ@186804|Peptostreptococcaceae	186801|Clostridia	S	PIN domain protein	yacL	-	-	-	-	-	-	-	-	-	-	-	PIN,PIN_4,TRAM
k141_2427_22	1280692.AUJL01000034_gene404	2.14e-41	140.0	COG1694@1|root,COG1694@2|Bacteria,1VBGH@1239|Firmicutes,24JEF@186801|Clostridia,36IV1@31979|Clostridiaceae	186801|Clostridia	S	Mazg nucleotide pyrophosphohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_2766_2	1487923.DP73_03455	7e-74	241.0	COG3464@1|root,COG4584@1|root,COG3464@2|Bacteria,COG4584@2|Bacteria,1VDMT@1239|Firmicutes,25H3E@186801|Clostridia	186801|Clostridia	L	Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISL3
k141_2766_3	1487923.DP73_03460	1.61e-62	195.0	COG3464@1|root,COG3464@2|Bacteria,1VNXH@1239|Firmicutes,24UY7@186801|Clostridia	186801|Clostridia	L	zinc-finger of transposase IS204/IS1001/IS1096/IS1165	-	-	-	-	-	-	-	-	-	-	-	-	zf-ISL3
k141_480_1	177437.HRM2_17190	4.04e-117	343.0	COG0047@1|root,COG0047@2|Bacteria,1MU4Y@1224|Proteobacteria,42MNY@68525|delta/epsilon subdivisions,2WJ6C@28221|Deltaproteobacteria,2MI5J@213118|Desulfobacterales	28221|Deltaproteobacteria	F	CobB/CobQ-like glutamine amidotransferase domain	purQ	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase_5
k141_480_2	1121396.KB893072_gene1238	3.85e-133	413.0	COG0046@1|root,COG1828@1|root,COG0046@2|Bacteria,COG1828@2|Bacteria,1MYN4@1224|Proteobacteria,42M08@68525|delta/epsilon subdivisions,2WITS@28221|Deltaproteobacteria,2MIFX@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C,PurS
k141_3146_1	635013.TherJR_2632	9.41e-84	268.0	COG0577@1|root,COG0577@2|Bacteria,1TPUU@1239|Firmicutes,2483J@186801|Clostridia,260DV@186807|Peptococcaceae	186801|Clostridia	V	ABC-type antimicrobial peptide transport system, permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
k141_3146_2	1007096.BAGW01000013_gene2540	1.14e-84	258.0	COG1136@1|root,COG1136@2|Bacteria,1TPBJ@1239|Firmicutes,248EZ@186801|Clostridia,2N6MS@216572|Oscillospiraceae	186801|Clostridia	V	ATPases associated with a variety of cellular activities	macB	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
k141_3146_3	515635.Dtur_0739	8.72e-19	96.3	COG0845@1|root,COG0845@2|Bacteria	2|Bacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
k141_3146_4	997350.HMPREF9129_1263	2.89e-191	554.0	COG0028@1|root,COG0028@2|Bacteria,1TQE8@1239|Firmicutes,2480U@186801|Clostridia,22GNM@1570339|Peptoniphilaceae	186801|Clostridia	H	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain	ilvB	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
k141_3146_5	1511.CLOST_1422	6.61e-241	680.0	COG0129@1|root,COG0129@2|Bacteria,1TP1R@1239|Firmicutes,247UC@186801|Clostridia,25SKM@186804|Peptostreptococcaceae	186801|Clostridia	H	Belongs to the IlvD Edd family	ilvD	-	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
k141_3146_6	1128398.Curi_c12340	1e-162	464.0	COG0059@1|root,COG0059@2|Bacteria,1TPI7@1239|Firmicutes,247RH@186801|Clostridia,267TH@186813|unclassified Clostridiales	186801|Clostridia	EH	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate	ilvC	-	1.1.1.86	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R03051,R04439,R04440,R05068,R05069,R05071	RC00726,RC00836,RC00837,RC01726	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS10005,iHN637.CLJU_RS10010	IlvC,IlvN
k141_3146_8	1121324.CLIT_13c00520	2.68e-193	553.0	COG1982@1|root,COG1982@2|Bacteria,1TNZ9@1239|Firmicutes,247RA@186801|Clostridia	186801|Clostridia	E	Orn Lys Arg decarboxylase major	speA	-	4.1.1.19	ko:K01585	ko00330,ko01100,map00330,map01100	M00133	R00566	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	OKR_DC_1,OKR_DC_1_C
k141_3146_9	1511.CLOST_0043	7.38e-70	213.0	COG1586@1|root,COG1586@2|Bacteria,1V3U2@1239|Firmicutes,24H9Q@186801|Clostridia	186801|Clostridia	E	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine	speH	-	4.1.1.50	ko:K01611	ko00270,ko00330,ko01100,map00270,map00330,map01100	M00034,M00133	R00178	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS10460	AdoMet_dc
k141_3146_10	1304284.L21TH_0235	1.31e-149	427.0	COG0421@1|root,COG0421@2|Bacteria,1TPG5@1239|Firmicutes,24827@186801|Clostridia,36FAN@31979|Clostridiaceae	186801|Clostridia	E	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	speE	-	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	Spermine_synt_N,Spermine_synth
k141_3146_11	1511.CLOST_0041	2.93e-146	418.0	COG0010@1|root,COG0010@2|Bacteria,1TP2A@1239|Firmicutes,2493V@186801|Clostridia	186801|Clostridia	E	Belongs to the arginase family	speB	-	3.5.3.11	ko:K01480	ko00330,ko01100,map00330,map01100	M00133	R01157	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
k141_3146_13	1499967.BAYZ01000174_gene5832	1.26e-16	90.5	COG3437@1|root,COG4191@1|root,COG5000@1|root,COG3437@2|Bacteria,COG4191@2|Bacteria,COG5000@2|Bacteria	2|Bacteria	T	phosphorelay sensor kinase activity	pleD	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0042802,GO:0044424,GO:0044464	2.7.7.65,4.6.1.1	ko:K01768,ko:K02488,ko:K17763	ko00230,ko02020,ko02025,ko04112,ko04113,ko04213,map00230,map02020,map02025,map04112,map04113,map04213	M00511,M00695	R00089,R00434,R08057	RC00295	ko00000,ko00001,ko00002,ko01000,ko02022,ko03021	-	-	-	GGDEF,HAMP,HATPase_c,HisKA,HisKA_3,PAS,PAS_4,PAS_9,Response_reg
k141_3146_14	589873.EP13_00325	8.45e-31	139.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,4664E@72275|Alteromonadaceae	1236|Gammaproteobacteria	T	GGDEF EAL domain-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,dCache_3
k141_3146_15	373994.Riv7116_5551	8.04e-20	94.7	COG2199@1|root,COG4191@1|root,COG3706@2|Bacteria,COG4191@2|Bacteria,1G4YP@1117|Cyanobacteria,1HR78@1161|Nostocales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
k141_3146_16	1031288.AXAA01000004_gene1827	5.5e-58	185.0	COG1905@1|root,COG1905@2|Bacteria,1V737@1239|Firmicutes,24HFB@186801|Clostridia,36IPU@31979|Clostridiaceae	186801|Clostridia	C	Thioredoxin-like [2Fe-2S] ferredoxin	-	-	1.6.5.3	ko:K00334	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx
k141_3146_17	903814.ELI_0845	1.81e-30	113.0	COG3411@1|root,COG3411@2|Bacteria,1V6DT@1239|Firmicutes,24M31@186801|Clostridia,25X30@186806|Eubacteriaceae	186801|Clostridia	C	Ferredoxin	-	-	1.12.1.3	ko:K17992	-	-	-	-	ko00000,ko01000	-	-	-	2Fe-2S_thioredx
k141_3146_18	1280390.CBQR020000146_gene3731	2.03e-270	759.0	COG1894@1|root,COG1894@2|Bacteria,1TQB0@1239|Firmicutes,4I6ZB@91061|Bacilli,26VMP@186822|Paenibacillaceae	91061|Bacilli	C	NADH dehydrogenase	-	-	1.12.1.3	ko:K18331	-	-	-	-	ko00000,ko01000	-	-	-	2Fe-2S_thioredx,Complex1_51K,Fer4,NADH_4Fe-4S,SLBB
k141_3146_19	350688.Clos_0930	8.25e-259	728.0	COG3383@1|root,COG4624@1|root,COG3383@2|Bacteria,COG4624@2|Bacteria,1TP6C@1239|Firmicutes,24897@186801|Clostridia,36DJB@31979|Clostridiaceae	186801|Clostridia	C	iron hydrogenase, small subunit	-	-	1.12.1.3,1.6.5.3	ko:K00336,ko:K18332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fe_hyd_SSU,Fe_hyd_lg_C,Fer2_4,Fer4,Fer4_7,Fer4_9,NADH-G_4Fe-4S_3
k141_4643_1	870967.VIS19158_16766	1.34e-80	245.0	COG0602@1|root,COG0602@2|Bacteria,1MUJ2@1224|Proteobacteria,1RNQZ@1236|Gammaproteobacteria,1XUXZ@135623|Vibrionales	135623|Vibrionales	H	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds	queE	-	4.3.99.3	ko:K10026	ko00790,ko01100,map00790,map01100	-	R10002	RC02989	ko00000,ko00001,ko01000,ko03016	-	-	-	Fer4_14,Radical_SAM
k141_4643_2	1187848.AJYQ01000155_gene3113	5.28e-128	368.0	COG0603@1|root,COG0603@2|Bacteria,1MU5V@1224|Proteobacteria,1RMG9@1236|Gammaproteobacteria,1XTZ0@135623|Vibrionales	135623|Vibrionales	F	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))	queC	-	6.3.4.20	ko:K06920	ko00790,ko01100,map00790,map01100	-	R09978	RC00959	ko00000,ko00001,ko01000,ko03016	-	-	-	QueC
k141_4643_3	1122134.KB893650_gene441	2.04e-30	134.0	COG2202@1|root,COG5001@1|root,COG2202@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1XHII@135619|Oceanospirillales	135619|Oceanospirillales	T	Diguanylate cyclase phosphodiesterase with PAS PAC	-	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp,EAL,GGDEF,PAS,PAS_3,PAS_9
k141_4643_4	945543.VIBR0546_15636	0.0	1273.0	COG0443@1|root,COG0443@2|Bacteria,1MXX7@1224|Proteobacteria,1RP0D@1236|Gammaproteobacteria,1XTBY@135623|Vibrionales	135623|Vibrionales	O	Belongs to the heat shock protein 70 family	-	-	-	-	-	-	-	-	-	-	-	-	DUF3731,HSP70
k141_4643_5	223926.28806430	0.0	917.0	COG0443@1|root,COG0443@2|Bacteria,1MXX7@1224|Proteobacteria,1RQ12@1236|Gammaproteobacteria,1XTFW@135623|Vibrionales	135623|Vibrionales	O	Belongs to the heat shock protein 70 family	-	-	-	-	-	-	-	-	-	-	-	-	HSP70
k141_4643_6	55601.VANGNB10_cI1365	1.08e-80	246.0	2CNUX@1|root,32SHU@2|Bacteria,1REYT@1224|Proteobacteria,1S2ZX@1236|Gammaproteobacteria,1XSGJ@135623|Vibrionales	135623|Vibrionales	S	Domain of unknown function (DUF2760)	VV12320	-	-	-	-	-	-	-	-	-	-	-	DUF2760
k141_4643_7	945543.VIBR0546_15616	1.37e-107	311.0	COG5018@1|root,COG5018@2|Bacteria,1NBZ1@1224|Proteobacteria,1T1XQ@1236|Gammaproteobacteria,1XUGB@135623|Vibrionales	135623|Vibrionales	L	Exonuclease	-	-	-	-	-	-	-	-	-	-	-	-	RNase_T
k141_4643_8	929558.SMGD1_1680	1.21e-117	358.0	COG0688@1|root,COG0688@2|Bacteria,1PCNR@1224|Proteobacteria,42NZ3@68525|delta/epsilon subdivisions,2YSTU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	Phosphatidylserine decarboxylase	-	-	4.1.1.65	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	M00093	R02055	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	PS_Dcarbxylase
k141_4643_9	1051646.VITU9109_16023	3.21e-67	232.0	COG4690@1|root,COG4690@2|Bacteria,1R4YQ@1224|Proteobacteria,1RNP0@1236|Gammaproteobacteria,1XSKC@135623|Vibrionales	135623|Vibrionales	M	Peptidase family C69	-	-	-	ko:K08659	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_C69
k141_4643_10	1500894.JQNN01000001_gene2575	3.23e-167	486.0	COG2957@1|root,COG2957@2|Bacteria	2|Bacteria	E	agmatine deiminase activity	-	GO:0003674,GO:0003824,GO:0004175,GO:0004197,GO:0004198,GO:0005488,GO:0005509,GO:0005575,GO:0005576,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008234,GO:0016787,GO:0019538,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0046872,GO:0070011,GO:0071704,GO:0140096,GO:1901564	3.4.22.37,3.5.3.12	ko:K08589,ko:K10536	ko00330,ko01100,ko01503,map00330,map01100,map01503	-	R01416	RC00177	ko00000,ko00001,ko01000,ko01002	-	-	-	PAD_porph,Peptidase_C25,Peptidase_C25_C,Propeptide_C25
k141_4643_11	243277.VC_2620	2.95e-278	769.0	COG0621@1|root,COG0621@2|Bacteria,1MU7N@1224|Proteobacteria,1RN46@1236|Gammaproteobacteria,1XVFI@135623|Vibrionales	135623|Vibrionales	J	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12	rimO	-	2.8.4.4	ko:K14441	-	-	R10652	RC00003,RC03217	ko00000,ko01000,ko03009	-	-	-	Radical_SAM,UPF0004
k141_4643_12	675814.VIC_001503	2.12e-55	177.0	COG4103@1|root,COG4103@2|Bacteria,1N6YZ@1224|Proteobacteria,1SD1K@1236|Gammaproteobacteria,1XXJC@135623|Vibrionales	135623|Vibrionales	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	TerB
k141_4643_13	575788.VS_1777	2.43e-34	123.0	2B24R@1|root,31UMW@2|Bacteria,1QSHI@1224|Proteobacteria,1THZZ@1236|Gammaproteobacteria,1XY1S@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_4643_14	1219065.VPR01S_01_02880	2.87e-91	272.0	COG1182@1|root,COG1182@2|Bacteria,1P59R@1224|Proteobacteria,1S337@1236|Gammaproteobacteria,1XW8V@135623|Vibrionales	135623|Vibrionales	C	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity	azoR	-	-	ko:K01118	-	-	-	-	ko00000,ko01000	-	-	-	Flavodoxin_2
k141_4643_15	674977.VMC_39840	0.0	2168.0	COG1643@1|root,COG1643@2|Bacteria,1MUEQ@1224|Proteobacteria,1RMU1@1236|Gammaproteobacteria,1XSCH@135623|Vibrionales	135623|Vibrionales	L	COG1643 HrpA-like helicases	hrpA	-	3.6.4.13	ko:K03578	-	-	-	-	ko00000,ko01000	-	-	-	DEAD,DUF3418,HA2,Helicase_C,OB_NTP_bind
k141_4643_16	675815.VOA_001981	1.62e-59	189.0	COG3637@1|root,COG3637@2|Bacteria,1RHVI@1224|Proteobacteria,1S6UY@1236|Gammaproteobacteria,1XVZ1@135623|Vibrionales	135623|Vibrionales	M	OmpA-like transmembrane domain	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl
k141_4643_17	1120931.KB893932_gene865	3.29e-63	202.0	COG0637@1|root,COG0637@2|Bacteria,1NF90@1224|Proteobacteria,1RNP8@1236|Gammaproteobacteria,1Y886@135625|Pasteurellales	135625|Pasteurellales	S	HAD-superfamily hydrolase, subfamily IA, variant 3	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
k141_4643_19	243277.VC_1414	9.39e-267	742.0	COG2317@1|root,COG2317@2|Bacteria,1MW7T@1224|Proteobacteria,1RQM5@1236|Gammaproteobacteria,1XTZ9@135623|Vibrionales	135623|Vibrionales	E	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues	-	-	3.4.17.19	ko:K01299	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M32
k141_4643_20	243277.VC_A0017	1.64e-113	326.0	COG3157@1|root,COG3157@2|Bacteria,1MXFB@1224|Proteobacteria,1RNKQ@1236|Gammaproteobacteria,1XVCS@135623|Vibrionales	135623|Vibrionales	S	COG3157 Hemolysin-coregulated protein	hcp	-	-	ko:K11903	ko02025,ko03070,map02025,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko02044	-	-	-	T6SS_HCP
k141_4643_21	55601.VANGNB10_cII0974c	1.73e-273	785.0	COG3409@1|root,COG3501@1|root,COG3409@2|Bacteria,COG3501@2|Bacteria,1MU7Q@1224|Proteobacteria,1RMZS@1236|Gammaproteobacteria,1XUHW@135623|Vibrionales	135623|Vibrionales	M	protein conserved in bacteria	vgrG1	GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0006464,GO:0006807,GO:0006996,GO:0007010,GO:0007015,GO:0008144,GO:0008150,GO:0008152,GO:0008154,GO:0009405,GO:0009987,GO:0016043,GO:0016874,GO:0016879,GO:0016881,GO:0017076,GO:0018149,GO:0018153,GO:0018193,GO:0018199,GO:0018205,GO:0018262,GO:0018995,GO:0019538,GO:0022411,GO:0030029,GO:0030036,GO:0030042,GO:0030430,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032984,GO:0033643,GO:0033646,GO:0035639,GO:0036094,GO:0036211,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0043624,GO:0043656,GO:0043657,GO:0043933,GO:0044215,GO:0044216,GO:0044217,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044419,GO:0046872,GO:0051261,GO:0051704,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:0097435,GO:1901265,GO:1901363,GO:1901564	-	ko:K11904	ko03070,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	PG_binding_1,Phage_GPD
k141_4643_22	675816.VIA_001718	5.25e-74	259.0	COG3179@1|root,COG3772@1|root,COG3179@2|Bacteria,COG3772@2|Bacteria,1N68W@1224|Proteobacteria,1SHSK@1236|Gammaproteobacteria,1XWST@135623|Vibrionales	135623|Vibrionales	G	lysozyme	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_3620_2	1348635.BBJY01000004_gene2891	1.38e-219	632.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,1XTM0@135623|Vibrionales	135623|Vibrionales	NT	methyl-accepting chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,CHASE3,HBM,MCPsignal
k141_1254_1	870967.VIS19158_18061	2.4e-75	240.0	COG3608@1|root,COG3608@2|Bacteria,1QUH0@1224|Proteobacteria,1RNXD@1236|Gammaproteobacteria,1XTMP@135623|Vibrionales	135623|Vibrionales	S	Succinylglutamate desuccinylase / Aspartoacylase family	-	-	-	-	-	-	-	-	-	-	-	-	AstE_AspA,Peptidase_M14
k141_1254_2	345073.VC395_A0955	8.42e-96	294.0	COG2354@1|root,COG2354@2|Bacteria,1MVYU@1224|Proteobacteria,1RMUZ@1236|Gammaproteobacteria,1XTCV@135623|Vibrionales	135623|Vibrionales	S	protein conserved in bacteria	yedI	-	-	ko:K09781	-	-	-	-	ko00000	-	-	-	DUF808
k141_1254_3	243277.VC_A0925	2.06e-200	560.0	COG0418@1|root,COG0418@2|Bacteria,1MUYP@1224|Proteobacteria,1RNEN@1236|Gammaproteobacteria,1XSNV@135623|Vibrionales	135623|Vibrionales	F	Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate	pyrC	GO:0003674,GO:0003824,GO:0004151,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
k141_1254_4	1147.D082_30390	6e-92	279.0	COG4748@1|root,COG4748@2|Bacteria,1G4QJ@1117|Cyanobacteria	1117|Cyanobacteria	S	Type I restriction enzyme R protein N terminus (HSDR_N)	-	-	-	ko:K07504	-	-	-	-	ko00000	-	-	-	HSDR_N,HSDR_N_2
k141_2521_1	243277.VC_2013	5.19e-34	129.0	COG1263@1|root,COG1264@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,1MY1V@1224|Proteobacteria,1RMYZ@1236|Gammaproteobacteria,1XV6P@135623|Vibrionales	135623|Vibrionales	G	COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific	ptsG	-	2.7.1.199	ko:K02778,ko:K02779	ko00010,ko00520,ko02060,ko05111,map00010,map00520,map02060,map05111	M00265	R02738	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.1.1.1	-	-	PTS_EIIB,PTS_EIIC
k141_2521_2	1116375.VEJY3_10645	1.08e-310	855.0	COG1263@1|root,COG1264@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,1MU2P@1224|Proteobacteria,1RNF4@1236|Gammaproteobacteria,1XUZI@135623|Vibrionales	135623|Vibrionales	G	COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific	-	-	2.7.1.199	ko:K20116,ko:K20117,ko:K20118	ko00010,ko00520,ko02060,map00010,map00520,map02060	M00809	R02738	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.1.1.13,4.A.1.1.14,4.A.1.1.9	-	-	PTS_EIIB,PTS_EIIC
k141_2521_3	1188252.AJYK01000065_gene2539	4.98e-54	174.0	2AW6Y@1|root,31N1Z@2|Bacteria,1QJTN@1224|Proteobacteria,1THV0@1236|Gammaproteobacteria,1XXN0@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	RDD
k141_2521_4	1219080.VEZ01S_21_00500	0.000379	46.6	2E0KP@1|root,31P2N@2|Bacteria,1QKRT@1224|Proteobacteria,1TIWG@1236|Gammaproteobacteria,1XZUE@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_2521_5	701176.VIBRN418_19043	9.05e-11	56.2	2AWZ9@1|root,31NX5@2|Bacteria,1QKKJ@1224|Proteobacteria,1TIQW@1236|Gammaproteobacteria,1XZH1@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_2521_6	55601.VANGNB10_cI1825	9.51e-285	786.0	COG0733@1|root,COG0733@2|Bacteria,1MUZJ@1224|Proteobacteria,1RPCT@1236|Gammaproteobacteria,1XU8H@135623|Vibrionales	135623|Vibrionales	U	Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family	-	-	-	ko:K03308	-	-	-	-	ko00000	2.A.22.4,2.A.22.5	-	-	SNF
k141_2521_7	1219065.VPR01S_03_01970	3.7e-156	452.0	COG4667@1|root,COG4667@2|Bacteria,1NU6Q@1224|Proteobacteria,1SKPI@1236|Gammaproteobacteria,1XUVM@135623|Vibrionales	135623|Vibrionales	S	esterase of the alpha-beta hydrolase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Patatin
k141_1255_1	1120970.AUBZ01000023_gene2832	1.55e-55	196.0	COG3250@1|root,COG3250@2|Bacteria,1MVBN@1224|Proteobacteria,1RMER@1236|Gammaproteobacteria,4654R@72275|Alteromonadaceae	1236|Gammaproteobacteria	G	Belongs to the glycosyl hydrolase 2 family	lacZ	GO:0000287,GO:0003674,GO:0003824,GO:0004553,GO:0004565,GO:0005488,GO:0005515,GO:0005575,GO:0005975,GO:0005984,GO:0005988,GO:0005990,GO:0008150,GO:0008152,GO:0009056,GO:0009311,GO:0009313,GO:0009341,GO:0009987,GO:0015925,GO:0016052,GO:0016787,GO:0016798,GO:0031420,GO:0032991,GO:0042802,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044275,GO:0046352,GO:0046872,GO:0071704,GO:1901575,GO:1902494	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	iAF1260.b0344,iB21_1397.B21_00302,iECBD_1354.ECBD_3313,iECB_1328.ECB_00298,iECDH1ME8569_1439.ECDH1ME8569_0331,iECD_1391.ECD_00298,iECNA114_1301.ECNA114_0327,iEcDH1_1363.EcDH1_3262,iJO1366.b0344,iJR904.b0344,iY75_1357.Y75_RS01775	Bgal_small_N,DUF4981,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
k141_820_1	1408287.AXUR01000010_gene1826	1.65e-101	309.0	COG2252@1|root,COG2252@2|Bacteria,37914@32066|Fusobacteria	32066|Fusobacteria	S	Psort location CytoplasmicMembrane, score 10.00	-	-	-	ko:K06901	-	-	-	-	ko00000,ko02000	2.A.1.40	-	-	Xan_ur_permease
k141_1544_1	345073.VC395_0385	3.38e-199	558.0	COG1600@1|root,COG1600@2|Bacteria,1MV1H@1224|Proteobacteria,1RMD9@1236|Gammaproteobacteria,1XSXR@135623|Vibrionales	135623|Vibrionales	C	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)	queG	GO:0003674,GO:0003824,GO:0006091,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009055,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016491,GO:0018130,GO:0019438,GO:0022900,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0052693,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	1.17.99.6	ko:K18979	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF1730,Fer4_16
k141_1544_2	575788.VS_0266	1.17e-87	261.0	COG0802@1|root,COG0802@2|Bacteria,1RGYU@1224|Proteobacteria,1S6IB@1236|Gammaproteobacteria,1XUDS@135623|Vibrionales	135623|Vibrionales	S	ATPase or kinase	yjeE	-	-	ko:K06925	-	-	-	-	ko00000,ko03016	-	-	-	TsaE
k141_1544_3	1517681.HW45_02900	6.59e-273	763.0	COG0860@1|root,COG1388@1|root,COG0860@2|Bacteria,COG1388@2|Bacteria,1MUQK@1224|Proteobacteria,1RMP1@1236|Gammaproteobacteria,1XU2J@135623|Vibrionales	135623|Vibrionales	M	N-acetylmuramoyl-L-alanine amidase	amiB	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	AMIN,Amidase_3,LysM
k141_1544_4	1348635.BBJY01000031_gene2100	3.46e-266	753.0	COG0323@1|root,COG0323@2|Bacteria,1MV61@1224|Proteobacteria,1RM89@1236|Gammaproteobacteria,1XTP3@135623|Vibrionales	135623|Vibrionales	L	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	mutL	GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391	-	ko:K03572	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	DNA_mis_repair,HATPase_c_3,MutL_C
k141_1544_8	29495.EA26_19940	2.59e-219	612.0	COG0330@1|root,COG0330@2|Bacteria,1MUM2@1224|Proteobacteria,1RMUG@1236|Gammaproteobacteria,1XU48@135623|Vibrionales	135623|Vibrionales	O	HflC and HflK could encode or regulate a protease	hflK	GO:0003674,GO:0003824,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:0140096,GO:1901564	-	ko:K04088	-	M00742	-	-	ko00000,ko00002,ko01000	-	-	-	Band_7,HflK_N
k141_1544_9	675815.VOA_003107	4.98e-184	517.0	COG0330@1|root,COG0330@2|Bacteria,1MV7R@1224|Proteobacteria,1RM8Z@1236|Gammaproteobacteria,1XTY8@135623|Vibrionales	135623|Vibrionales	O	HflC and HflK could regulate a protease	hflC	GO:0003674,GO:0003824,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:0140096,GO:1901564	-	ko:K04087	-	M00742	-	-	ko00000,ko00002,ko01000	-	-	-	Band_7
k141_1544_10	223926.28807790	1.94e-23	91.3	COG2900@1|root,COG2900@2|Bacteria,1NGFM@1224|Proteobacteria,1SGAM@1236|Gammaproteobacteria,1XYDM@135623|Vibrionales	135623|Vibrionales	S	Belongs to the SlyX family	slyX	-	-	ko:K03745	-	-	-	-	ko00000	-	-	-	SlyX
k141_1544_11	674977.VMC_01510	6.17e-74	236.0	COG2319@1|root,COG2319@2|Bacteria,1PDT0@1224|Proteobacteria,1RV85@1236|Gammaproteobacteria,1XTYR@135623|Vibrionales	135623|Vibrionales	S	COG2319 FOG WD40 repeat	-	-	-	-	-	-	-	-	-	-	-	-	WD40
k141_2253_1	754476.Q7A_917	1.98e-192	535.0	28KS3@1|root,2ZA9J@2|Bacteria,1R5YV@1224|Proteobacteria,1SMNA@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_2253_2	1268239.PALB_29250	9.8e-150	443.0	COG1196@1|root,COG1196@2|Bacteria,1R25H@1224|Proteobacteria,1S41G@1236|Gammaproteobacteria	1236|Gammaproteobacteria	D	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_2253_3	1121930.AQXG01000001_gene1305	1.72e-83	257.0	COG0639@1|root,COG0639@2|Bacteria,4NNXX@976|Bacteroidetes	976|Bacteroidetes	T	Calcineurin-like phosphoesterase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos_2
k141_2253_4	223926.28806790	2.49e-78	233.0	COG3324@1|root,COG3324@2|Bacteria,1N0AD@1224|Proteobacteria,1S8YM@1236|Gammaproteobacteria,1XY2Z@135623|Vibrionales	135623|Vibrionales	S	Glyoxalase-like domain	-	-	-	ko:K06996	-	-	-	-	ko00000	-	-	-	Glyoxalase
k141_2253_5	1122139.KB907883_gene323	1.36e-97	304.0	COG1520@1|root,COG1520@2|Bacteria,1NUMC@1224|Proteobacteria,1SNF6@1236|Gammaproteobacteria,1XPA2@135619|Oceanospirillales	135619|Oceanospirillales	S	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_2253_6	1116375.VEJY3_06725	2.71e-124	360.0	COG0726@1|root,COG0726@2|Bacteria,1MV3V@1224|Proteobacteria,1RPKM@1236|Gammaproteobacteria,1XTIJ@135623|Vibrionales	135623|Vibrionales	G	Polysaccharide deacetylase	-	-	3.5.1.104	ko:K22278	-	-	-	-	ko00000,ko01000	-	-	-	Polysacc_deac_1
k141_1929_1	1348635.BBJY01000001_gene2599	3.88e-53	177.0	COG1566@1|root,COG1566@2|Bacteria,1MU7I@1224|Proteobacteria,1RPV2@1236|Gammaproteobacteria,1XUFT@135623|Vibrionales	135623|Vibrionales	V	Secretion protein	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
k141_1929_2	1191299.AJYX01000097_gene1712	1.1e-51	168.0	COG1846@1|root,COG1846@2|Bacteria,1N78T@1224|Proteobacteria,1S26B@1236|Gammaproteobacteria,1XX2C@135623|Vibrionales	135623|Vibrionales	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	ko:K06075	-	-	-	-	ko00000,ko03000	-	-	-	MarR
k141_1929_3	349106.PsycPRwf_1499	4.58e-60	200.0	COG0477@1|root,COG2814@2|Bacteria,1MU9G@1224|Proteobacteria,1RPHV@1236|Gammaproteobacteria,3NKD6@468|Moraxellaceae	1236|Gammaproteobacteria	EGP	Major Facilitator Superfamily	sotB	-	-	ko:K03445,ko:K08159	-	-	-	-	ko00000,ko02000	2.A.1.2.15,2.A.1.2.18,2.A.1.2.26	-	-	MFS_1
k141_4644_1	643562.Daes_0589	1.62e-182	520.0	COG0477@1|root,COG2814@2|Bacteria,1MU9G@1224|Proteobacteria,42SJ6@68525|delta/epsilon subdivisions,2WPXV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	EGP	Sugar (and other) transporter	mxcK	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
k141_4644_2	439235.Dalk_4689	1.92e-43	147.0	COG0826@1|root,COG0826@2|Bacteria,1P11K@1224|Proteobacteria,431AH@68525|delta/epsilon subdivisions,2WX58@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Protein of unknown function (DUF3795)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3795
k141_4256_1	1517681.HW45_18380	3.01e-36	127.0	COG0589@1|root,COG0589@2|Bacteria,1MV6Y@1224|Proteobacteria,1RQQ7@1236|Gammaproteobacteria,1XWVC@135623|Vibrionales	135623|Vibrionales	T	COG0589 Universal stress protein UspA and related nucleotide-binding proteins	uspA	-	-	ko:K06149	-	-	-	-	ko00000	-	-	-	Usp
k141_2524_2	1499689.CCNN01000009_gene2759	1.59e-48	165.0	COG1108@1|root,COG1108@2|Bacteria,1TPZB@1239|Firmicutes,2487Y@186801|Clostridia,36GX3@31979|Clostridiaceae	186801|Clostridia	P	ABC 3 transport family	troD	-	-	ko:K09819,ko:K11709,ko:K19976	ko02010,map02010	M00243,M00319,M00792	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15,3.A.1.15.15	-	-	ABC-3,Fe_dep_repr_C,Fe_dep_repress
k141_1256_1	555779.Dthio_PD0736	8.38e-106	317.0	COG1943@1|root,COG1943@2|Bacteria,1MVUV@1224|Proteobacteria,43B13@68525|delta/epsilon subdivisions,2WS1C@28221|Deltaproteobacteria	1224|Proteobacteria	L	COG1943 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_288_2	243277.VC_2068	1.5e-235	662.0	COG1419@1|root,COG1419@2|Bacteria,1MUQW@1224|Proteobacteria,1RMUU@1236|Gammaproteobacteria,1XTQT@135623|Vibrionales	135623|Vibrionales	N	Flagellar biosynthesis	flhF	-	-	ko:K02404	-	-	-	-	ko00000,ko02035	-	-	-	SRP54
k141_288_3	243277.VC_2067	1.02e-186	522.0	COG0455@1|root,COG0455@2|Bacteria,1R8IW@1224|Proteobacteria,1RMZ2@1236|Gammaproteobacteria,1XTYQ@135623|Vibrionales	135623|Vibrionales	D	Belongs to the ParA family	flhG	-	-	ko:K04562	-	-	-	-	ko00000,ko02035	-	-	-	ParA
k141_1931_1	246969.TAM4_1628	2.95e-33	134.0	COG4928@1|root,arCOG10127@2157|Archaea,2XZB5@28890|Euryarchaeota	28890|Euryarchaeota	S	KAP P-loop domain protein	-	-	-	-	-	-	-	-	-	-	-	-	KAP_NTPase
k141_821_1	1121459.AQXE01000001_gene2688	9.73e-148	425.0	COG1250@1|root,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,42M6J@68525|delta/epsilon subdivisions,2WJZQ@28221|Deltaproteobacteria,2ME3G@213115|Desulfovibrionales	28221|Deltaproteobacteria	I	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain	-	-	1.1.1.108,1.1.1.157	ko:K00074,ko:K17735	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
k141_821_2	67281.JNZZ01000016_gene6336	3.12e-29	112.0	COG0824@1|root,COG0824@2|Bacteria,2ISIV@201174|Actinobacteria,41BV3@629295|Streptomyces griseus group	201174|Actinobacteria	S	Thioesterase-like superfamily	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT_2
k141_821_3	443144.GM21_1262	7.63e-29	107.0	COG0607@1|root,COG0607@2|Bacteria,1RM5B@1224|Proteobacteria,42TBJ@68525|delta/epsilon subdivisions,2WPIJ@28221|Deltaproteobacteria,43VER@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
k141_2254_1	945543.VIBR0546_11392	4.23e-95	283.0	COG4181@1|root,COG4181@2|Bacteria,1MXG9@1224|Proteobacteria,1RMG1@1236|Gammaproteobacteria,1XU0B@135623|Vibrionales	135623|Vibrionales	Q	ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component	ybbA	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
k141_2254_2	55601.VANGNB10_cII0741c	1.06e-85	280.0	COG3127@1|root,COG3127@2|Bacteria,1MU9R@1224|Proteobacteria,1RM8Y@1236|Gammaproteobacteria,1XSX0@135623|Vibrionales	135623|Vibrionales	Q	ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX
k141_290_1	1410676.JNKL01000007_gene209	6.18e-25	104.0	COG0619@1|root,COG0619@2|Bacteria,1RDKG@1224|Proteobacteria,1SPT4@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	Cobalt transport protein	-	-	-	ko:K16785	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	CbiQ
k141_3624_1	76114.ebA6328	5.06e-18	87.0	COG3850@1|root,COG5001@1|root,COG3850@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,2KV1U@206389|Rhodocyclales	206389|Rhodocyclales	T	GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF,PAS_9,Response_reg
k141_589_7	1001530.BACE01000001_gene3595	5.51e-194	546.0	COG0502@1|root,COG0502@2|Bacteria,1MXK0@1224|Proteobacteria,1RNTV@1236|Gammaproteobacteria,1XV3B@135623|Vibrionales	135623|Vibrionales	C	COG1060 Thiamine biosynthesis enzyme ThiH and related	thiH	-	4.1.99.19	ko:K03150	ko00730,ko01100,map00730,map01100	-	R10246	RC01434,RC03095	ko00000,ko00001,ko01000	-	-	-	BATS,Radical_SAM
k141_589_8	1348635.BBJY01000028_gene2089	2.64e-130	376.0	COG2022@1|root,COG2022@2|Bacteria,1N0N5@1224|Proteobacteria,1RMPD@1236|Gammaproteobacteria,1XT63@135623|Vibrionales	135623|Vibrionales	H	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S	thiG	GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.8.1.10	ko:K03149	ko00730,ko01100,map00730,map01100	-	R10247	RC03096,RC03097,RC03461	ko00000,ko00001,ko01000	-	-	-	ThiG
k141_589_9	675814.VIC_000404	5.92e-20	82.0	COG2104@1|root,COG2104@2|Bacteria,1NG8E@1224|Proteobacteria,1SGCU@1236|Gammaproteobacteria,1XYZ1@135623|Vibrionales	135623|Vibrionales	H	COG2104 Sulfur transfer protein involved in thiamine biosynthesis	thiS	-	-	ko:K03154	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
k141_589_10	1205908.AKXW01000110_gene1467	7.85e-75	235.0	COG0476@1|root,COG0476@2|Bacteria,1MW7H@1224|Proteobacteria,1RPJ3@1236|Gammaproteobacteria,1XV7V@135623|Vibrionales	135623|Vibrionales	H	COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2	thiF	-	2.7.7.73	ko:K03148	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07459	RC00043	ko00000,ko00001,ko01000	-	-	-	ThiF
k141_589_11	243277.VC_0062	6.52e-79	257.0	COG0352@1|root,COG0352@2|Bacteria,1QTW3@1224|Proteobacteria,1T1YB@1236|Gammaproteobacteria,1XSWF@135623|Vibrionales	135623|Vibrionales	H	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)	thiE	-	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	TMP-TENI
k141_4961_1	1304885.AUEY01000016_gene3039	6.23e-261	732.0	COG0446@1|root,COG0607@1|root,COG0446@2|Bacteria,COG0607@2|Bacteria,1NR3M@1224|Proteobacteria,42N3G@68525|delta/epsilon subdivisions,2WIS9@28221|Deltaproteobacteria,2MJBX@213118|Desulfobacterales	28221|Deltaproteobacteria	P	PFAM FAD-dependent pyridine nucleotide-disulfide oxidoreductase, pyridine nucleotide-disulfide oxidoreductase dimerization region, Pyridine nucleotide-disulphide oxidoreductase, FAD NAD(P)-binding domain, Rhodanese-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Pyr_redox_dim,Rhodanese
k141_5232_1	1121448.DGI_1416	8.69e-57	196.0	COG0247@1|root,COG1139@1|root,COG0247@2|Bacteria,COG1139@2|Bacteria,1MV6J@1224|Proteobacteria,42MN2@68525|delta/epsilon subdivisions,2WIMJ@28221|Deltaproteobacteria,2M99N@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	LUD domain	-	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_7,Fer4_8,LUD_dom
k141_5232_2	485915.Dret_1032	8.76e-42	146.0	COG1556@1|root,COG1556@2|Bacteria,1RCQZ@1224|Proteobacteria,42R0J@68525|delta/epsilon subdivisions,2WMNB@28221|Deltaproteobacteria,2MB25@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Lactate utilization protein B C	-	-	-	ko:K00782	-	-	-	-	ko00000	-	-	-	LUD_dom
k141_2268_1	1304888.ATWF01000002_gene339	2.68e-36	130.0	COG2834@1|root,COG2834@2|Bacteria,2GG12@200930|Deferribacteres	200930|Deferribacteres	M	Outer membrane lipoprotein-sorting protein	-	-	-	-	-	-	-	-	-	-	-	-	LolA_like
k141_2268_2	1304888.ATWF01000002_gene340	6.78e-61	207.0	COG1033@1|root,COG1033@2|Bacteria,2GFIN@200930|Deferribacteres	200930|Deferribacteres	K	Sterol-sensing domain of SREBP cleavage-activation	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
k141_2843_2	888059.HMPREF9071_2214	1.22e-06	49.7	2EEPW@1|root,338HK@2|Bacteria,4P2HW@976|Bacteroidetes,1IF15@117743|Flavobacteriia,1ES1M@1016|Capnocytophaga	976|Bacteroidetes	S	EthD domain	-	-	-	-	-	-	-	-	-	-	-	-	EthD,SnoaL_2
k141_2843_3	1232410.KI421412_gene389	1.19e-92	301.0	COG1629@1|root,COG4771@2|Bacteria,1MXAE@1224|Proteobacteria,43BVQ@68525|delta/epsilon subdivisions,2WKWT@28221|Deltaproteobacteria,43S1T@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	TonB-dependent Receptor Plug Domain	-	-	-	-	-	-	-	-	-	-	-	-	Plug
k141_318_1	1232437.KL661961_gene3041	1.17e-91	289.0	COG0493@1|root,COG3383@1|root,COG0493@2|Bacteria,COG3383@2|Bacteria,1MU2H@1224|Proteobacteria,42M6X@68525|delta/epsilon subdivisions,2X6YD@28221|Deltaproteobacteria,2MHMN@213118|Desulfobacterales	28221|Deltaproteobacteria	E	PFAM Pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_20,Pyr_redox_2
k141_590_1	1304885.AUEY01000028_gene2820	2.46e-176	501.0	COG1541@1|root,COG1541@2|Bacteria,1MV1W@1224|Proteobacteria,42NKD@68525|delta/epsilon subdivisions,2WIWV@28221|Deltaproteobacteria,2MIVW@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)	paaK-2	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	iAF987.Gmet_1825	AMP-binding,AMP-binding_C_2
k141_3240_1	596152.DesU5LDRAFT_0204	2.8e-21	97.8	COG0642@1|root,COG2205@2|Bacteria,1MW8M@1224|Proteobacteria,42R77@68525|delta/epsilon subdivisions,2WMVR@28221|Deltaproteobacteria,2MAKU@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	Integral membrane sensor signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
k141_5434_3	796606.BMMGA3_13460	8.6e-99	295.0	COG1187@1|root,COG1187@2|Bacteria,1TQZ2@1239|Firmicutes,4H9VU@91061|Bacilli,1ZCAM@1386|Bacillus	91061|Bacilli	J	Belongs to the pseudouridine synthase RsuA family	rsuA	GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	5.4.99.19	ko:K06183	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
k141_5434_4	1286171.EAL2_c07350	3.28e-91	276.0	COG1387@1|root,COG1387@2|Bacteria,1TQ33@1239|Firmicutes,249TZ@186801|Clostridia,25WCW@186806|Eubacteriaceae	186801|Clostridia	E	COG1387 Histidinol phosphatase and related hydrolases of the PHP family	-	-	-	ko:K04477	-	-	-	-	ko00000	-	-	-	PHP
k141_5434_5	1121324.CLIT_10c03820	3.66e-188	538.0	COG2265@1|root,COG2265@2|Bacteria,1TP4H@1239|Firmicutes,248B4@186801|Clostridia,25QXJ@186804|Peptostreptococcaceae	186801|Clostridia	H	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	rumA	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TRAM,tRNA_U5-meth_tr
k141_5434_6	1499683.CCFF01000014_gene3819	7.4e-72	224.0	COG1878@1|root,COG1878@2|Bacteria,1TSXB@1239|Firmicutes,24B80@186801|Clostridia,36DH0@31979|Clostridiaceae	186801|Clostridia	S	PFAM cyclase family protein	-	-	-	-	-	-	-	-	-	-	-	-	Cyclase
k141_5434_7	592027.CLG_A0016	1.78e-119	353.0	COG3240@1|root,COG3240@2|Bacteria	2|Bacteria	I	lipase activity	-	-	-	ko:K21831	-	-	-	-	ko00000	-	-	-	Lipase_GDSL
k141_5434_8	756499.Desde_4181	6.59e-166	499.0	COG0840@1|root,COG0840@2|Bacteria,1TP5A@1239|Firmicutes,247S3@186801|Clostridia,2642Q@186807|Peptococcaceae	186801|Clostridia	NT	Methyl-accepting chemotaxis protein (MCP) signaling domain	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal,dCache_1
k141_5434_9	1487921.DP68_17855	3.27e-146	429.0	COG0635@1|root,COG0635@2|Bacteria,1TUUY@1239|Firmicutes,2490N@186801|Clostridia,36GCR@31979|Clostridiaceae	186801|Clostridia	H	coproporphyrinogen III oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
k141_5434_10	350688.Clos_2493	1.03e-106	328.0	COG1251@1|root,COG1251@2|Bacteria,1UI2I@1239|Firmicutes,25EB3@186801|Clostridia,36UJ1@31979|Clostridiaceae	186801|Clostridia	C	PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase	nasD	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0015044,GO:0016491,GO:0016730,GO:0016731,GO:0017144,GO:0022900,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0072592,GO:0097159,GO:1901265,GO:1901363	1.6.3.4,1.7.1.15	ko:K00362,ko:K22405	ko00910,ko01120,map00910,map01120	M00530	R00787	RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	Pyr_redox_2
k141_5434_11	1286171.EAL2_808p06440	1.8e-79	273.0	COG0840@1|root,COG0840@2|Bacteria,1TP5A@1239|Firmicutes,247S3@186801|Clostridia,25X4C@186806|Eubacteriaceae	186801|Clostridia	NT	Cache domain	mcpC3	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal,dCache_1,sCache_2
k141_5434_12	592027.CLG_B2084	5.45e-79	255.0	COG5438@1|root,COG5438@2|Bacteria,1TPEV@1239|Firmicutes,249SW@186801|Clostridia,36GKC@31979|Clostridiaceae	186801|Clostridia	S	YibE F family protein	-	-	-	-	-	-	-	-	-	-	-	-	YibE_F
k141_5434_13	1280692.AUJL01000016_gene1150	1.47e-183	537.0	COG0737@1|root,COG0737@2|Bacteria,1TPV2@1239|Firmicutes,2491Y@186801|Clostridia,36ERD@31979|Clostridiaceae	186801|Clostridia	F	Belongs to the 5'-nucleotidase family	-	-	3.1.3.6,3.1.4.16	ko:K01119	ko00230,ko00240,map00230,map00240	-	R01562,R01877,R02148,R02370,R03537,R03538,R03929,R05135	RC00078,RC00296	ko00000,ko00001,ko01000	-	-	-	5_nucleotid_C,Gram_pos_anchor,LysM,Metallophos
k141_5434_15	386415.NT01CX_1252	2.75e-156	456.0	COG1757@1|root,COG1757@2|Bacteria,1TQPI@1239|Firmicutes,2495U@186801|Clostridia,36E2J@31979|Clostridiaceae	186801|Clostridia	C	hmm pf03553	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_antiporter
k141_5434_16	1499968.TCA2_2046	3.66e-27	111.0	COG0664@1|root,COG0664@2|Bacteria,1UEKS@1239|Firmicutes,4HCZE@91061|Bacilli,26SZB@186822|Paenibacillaceae	91061|Bacilli	K	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Crp_2,cNMP_binding
k141_5435_1	96561.Dole_0344	1.24e-74	246.0	COG0370@1|root,COG0370@2|Bacteria,1MUZC@1224|Proteobacteria,42MCY@68525|delta/epsilon subdivisions,2WIWJ@28221|Deltaproteobacteria,2MIW3@213118|Desulfobacterales	28221|Deltaproteobacteria	P	transporter of a GTP-driven Fe(2 ) uptake system	feoB-2	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoB_C,FeoB_N,Gate
k141_5435_2	1265505.ATUG01000002_gene2039	1.2e-18	85.9	COG0735@1|root,COG1918@1|root,COG0735@2|Bacteria,COG1918@2|Bacteria,1RDWJ@1224|Proteobacteria,42P61@68525|delta/epsilon subdivisions,2X5PQ@28221|Deltaproteobacteria,2MJ7H@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Belongs to the Fur family	-	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR,FeoA
k141_5436_1	945543.VIBR0546_19564	1.95e-268	754.0	COG2838@1|root,COG2838@2|Bacteria,1MV6Q@1224|Proteobacteria,1RPG4@1236|Gammaproteobacteria,1XUW0@135623|Vibrionales	135623|Vibrionales	C	Isocitrate dehydrogenase	icd	-	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	IDH
k141_5437_1	1286632.P278_33700	1.65e-314	860.0	28I9J@1|root,2Z8C8@2|Bacteria,4P06R@976|Bacteroidetes,1I7XB@117743|Flavobacteriia	976|Bacteroidetes	S	Bacteriophage replication gene A protein (GPA)	-	-	-	-	-	-	-	-	-	-	-	-	Phage_GPA
k141_5437_2	1288298.rosmuc_01659	6.62e-188	527.0	2DBBW@1|root,2Z8AR@2|Bacteria,1R492@1224|Proteobacteria,2UP8C@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Microvirus H protein (pilot protein)	-	-	-	-	-	-	-	-	-	-	-	-	Microvir_H
k141_5437_3	1286632.P278_33640	2.15e-124	354.0	28HGS@1|root,2Z7SJ@2|Bacteria,4NERU@976|Bacteroidetes,1HZIZ@117743|Flavobacteriia	976|Bacteroidetes	S	Major spike protein (G protein)	-	-	-	-	-	-	-	-	-	-	-	-	Phage_G
k141_5437_4	1270196.JCKI01000013_gene3205	0.0	889.0	28IN7@1|root,2Z8NM@2|Bacteria,4NHTH@976|Bacteroidetes	976|Bacteroidetes	S	Capsid protein (F protein)	-	-	-	-	-	-	-	-	-	-	-	-	Phage_F
k141_5437_5	1286632.P278_33670	1.35e-19	79.0	2EFW9@1|root,339NJ@2|Bacteria,4P71N@976|Bacteroidetes,1I6VT@117743|Flavobacteriia	976|Bacteroidetes	S	Microvirus J protein	-	-	-	-	-	-	-	-	-	-	-	-	Microvir_J
k141_5437_6	1288298.rosmuc_01661	4.9e-103	298.0	28HVF@1|root,2Z81Q@2|Bacteria,1NZPF@1224|Proteobacteria	1224|Proteobacteria	S	Bacteriophage scaffolding protein D	-	-	-	-	-	-	-	-	-	-	-	-	gpD
k141_5437_7	1453503.AU05_02695	3.63e-29	104.0	2FFHF@1|root,347EX@2|Bacteria,1P1ED@1224|Proteobacteria	1224|Proteobacteria	S	Bacteriophage protein K	-	-	-	-	-	-	-	-	-	-	-	-	Protein_K
k141_5437_8	1270193.JARP01000011_gene3662	3.59e-76	227.0	2CFW4@1|root,32Q75@2|Bacteria,4PDAR@976|Bacteroidetes,1IDTP@117743|Flavobacteriia,2NZ6D@237|Flavobacterium	976|Bacteroidetes	S	Scaffold protein B	-	-	-	-	-	-	-	-	-	-	-	-	Phage_B
k141_5440_2	1184267.A11Q_575	2.71e-16	79.0	COG1699@1|root,COG1699@2|Bacteria,1N9E7@1224|Proteobacteria,42V88@68525|delta/epsilon subdivisions,2MT3S@213481|Bdellovibrionales,2WR7H@28221|Deltaproteobacteria	213481|Bdellovibrionales	T	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum	fliW	-	-	ko:K13626	-	-	-	-	ko00000,ko02035	-	-	-	FliW
k141_5440_3	1121324.CLIT_13c00810	1.67e-14	68.9	COG1551@1|root,COG1551@2|Bacteria	2|Bacteria	T	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding	csrA	-	-	ko:K03563	ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03019	-	-	-	CsrA
k141_5440_4	562743.JH976434_gene1127	8.64e-65	211.0	COG1344@1|root,COG1344@2|Bacteria,1TP9Z@1239|Firmicutes,4HCW9@91061|Bacilli	91061|Bacilli	N	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella	-	-	-	ko:K02406	ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flagellin_C,Flagellin_N
k141_5441_1	1304877.KI519400_gene1078	5.45e-10	66.2	COG2931@1|root,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,2TRVY@28211|Alphaproteobacteria,3K64C@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	Q	Putative Ig domain	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin,HCBP_related,He_PIG,HemolysinCabind
k141_5112_1	97139.C824_01068	2.6e-19	88.6	COG1092@1|root,COG1092@2|Bacteria,1TPUD@1239|Firmicutes,2480X@186801|Clostridia,36W22@31979|Clostridiaceae	186801|Clostridia	H	S-adenosylmethionine-dependent methyltransferase	rlmL_1	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
k141_5113_1	1517681.HW45_18165	2.11e-100	307.0	COG1757@1|root,COG1757@2|Bacteria,1MX0T@1224|Proteobacteria,1RN8E@1236|Gammaproteobacteria,1XSIG@135623|Vibrionales	135623|Vibrionales	C	Na H antiporter	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_antiporter
k141_4773_1	1209072.ALBT01000031_gene1804	6.51e-63	203.0	COG0189@1|root,COG0189@2|Bacteria,1MVDU@1224|Proteobacteria,1RR7D@1236|Gammaproteobacteria,1FFYN@10|Cellvibrio	1236|Gammaproteobacteria	H	Sugar-transfer associated ATP-grasp	PA1766	-	-	-	-	-	-	-	-	-	-	-	ATPgrasp_ST
k141_3070_1	1191299.AJYX01000097_gene1713	1.99e-79	246.0	COG1566@1|root,COG1566@2|Bacteria,1MU7I@1224|Proteobacteria,1RPV2@1236|Gammaproteobacteria,1XUFT@135623|Vibrionales	135623|Vibrionales	V	Secretion protein	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
k141_3070_2	1278307.KB906999_gene39	2.25e-117	348.0	28HJP@1|root,2Z7UT@2|Bacteria,1MWM4@1224|Proteobacteria,1RQNG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF2955)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2955,FUSC_2
k141_14_2	1219065.VPR01S_07_01040	6.5e-57	179.0	2AW5Q@1|root,31N0Q@2|Bacteria,1QJSF@1224|Proteobacteria,1THTS@1236|Gammaproteobacteria,1XXI7@135623|Vibrionales	135623|Vibrionales	S	Protein of unknown function (DUF3319)	VPA0887	-	-	-	-	-	-	-	-	-	-	-	DUF3319
k141_14_3	29495.EA26_11450	2.02e-52	166.0	COG0023@1|root,COG0023@2|Bacteria,1MZ8T@1224|Proteobacteria,1S929@1236|Gammaproteobacteria,1XXTP@135623|Vibrionales	135623|Vibrionales	J	COG0023 Translation initiation factor 1 (eIF-1 SUI1) and related proteins	yciH	-	-	ko:K03113	ko03013,map03013	-	-	-	ko00000,ko00001,ko03012	-	-	-	SUI1
k141_687_1	614083.AWQR01000033_gene2871	5.63e-65	229.0	COG0642@1|root,COG5002@1|root,COG0642@2|Bacteria,COG2205@2|Bacteria,COG5002@2|Bacteria,1NRP8@1224|Proteobacteria,2VGZQ@28216|Betaproteobacteria,4AA9F@80864|Comamonadaceae	28216|Betaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	4HB_MCP_1,GAF_2,HAMP,HATPase_c,HisKA,Hpt,PAS,PAS_4,PAS_9,Response_reg
k141_687_3	349521.HCH_01310	7.16e-47	169.0	COG1629@1|root,COG4771@2|Bacteria,1MX42@1224|Proteobacteria,1RQ2K@1236|Gammaproteobacteria,1XJ0J@135619|Oceanospirillales	135619|Oceanospirillales	P	TonB dependent receptor	-	-	-	ko:K16087	-	-	-	-	ko00000,ko02000	1.B.14.2	-	-	Plug,TonB_dep_Rec
k141_3071_1	1124983.PFLCHA0_c15940	2.52e-18	86.3	COG2207@1|root,COG3449@1|root,COG2207@2|Bacteria,COG3449@2|Bacteria,1MWTF@1224|Proteobacteria,1RMKE@1236|Gammaproteobacteria,1YPKQ@136843|Pseudomonas fluorescens group	1236|Gammaproteobacteria	K	Transcriptional regulator, AraC family	-	-	-	ko:K13652	-	-	-	-	ko00000,ko03000	-	-	-	GyrI-like,HTH_18
k141_1025_1	675816.VIA_000141	7.28e-100	311.0	COG0422@1|root,COG0422@2|Bacteria,1MUVV@1224|Proteobacteria,1RP1F@1236|Gammaproteobacteria,1XSWD@135623|Vibrionales	135623|Vibrionales	H	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction	thiC	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.99.17	ko:K03147	ko00730,ko01100,map00730,map01100	M00127	R03472	RC03251,RC03252	ko00000,ko00001,ko00002,ko01000	-	-	-	ThiC-associated,ThiC_Rad_SAM
k141_1025_2	870967.VIS19158_13707	5.8e-70	213.0	COG0239@1|root,COG0239@2|Bacteria,1MZNH@1224|Proteobacteria,1S8RQ@1236|Gammaproteobacteria,1XXA0@135623|Vibrionales	135623|Vibrionales	D	Important for reducing fluoride concentration in the cell, thus reducing its toxicity	crcB	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425	-	ko:K06199	-	-	-	-	ko00000,ko02000	1.A.43.1,1.A.43.2,1.A.43.3	-	-	CRCB
k141_3752_1	1138822.PL11_09970	6.5e-08	55.8	COG1947@1|root,COG1947@2|Bacteria,1TPXV@1239|Firmicutes,4HAV8@91061|Bacilli,3F43W@33958|Lactobacillaceae	91061|Bacilli	F	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol	ispE	GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515	2.7.1.148	ko:K00919,ko:K16924	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096,M00582	R05634	RC00002,RC01439	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.29	-	iYO844.BSU00460	GHMP_kinases_C,GHMP_kinases_N
k141_3752_2	96561.Dole_2817	3.94e-150	431.0	COG0462@1|root,COG0462@2|Bacteria,1MW21@1224|Proteobacteria,42MI2@68525|delta/epsilon subdivisions,2WJ5W@28221|Deltaproteobacteria,2MIJR@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	prs	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2848	Pribosyl_synth,Pribosyltran_N
k141_3752_3	1234595.C725_0637	1.09e-34	129.0	COG1825@1|root,COG1825@2|Bacteria,1RDH0@1224|Proteobacteria,2U5P0@28211|Alphaproteobacteria,4BQBF@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	J	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance	ctc	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02897	ko03010,map03010	M00178	-	-	ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L25p,Ribosomal_TL5_C
k141_3752_4	1504823.CCMM01000011_gene1418	4.94e-62	197.0	COG0193@1|root,COG0193@2|Bacteria,2NPQ7@2323|unclassified Bacteria	2|Bacteria	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	GO:0003674,GO:0003824,GO:0004045,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0016787,GO:0016788,GO:0040007,GO:0044464,GO:0052689,GO:0071944,GO:0140098,GO:0140101	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
k141_3752_5	1304885.AUEY01000005_gene827	0.0	970.0	COG3808@1|root,COG3808@2|Bacteria,1MUQ3@1224|Proteobacteria,42N1H@68525|delta/epsilon subdivisions,2WJ0R@28221|Deltaproteobacteria,2MHVX@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase
k141_3752_6	643562.Daes_3338	6.24e-26	107.0	COG0809@1|root,COG0809@2|Bacteria,1MUH3@1224|Proteobacteria,42MMG@68525|delta/epsilon subdivisions,2WJ9W@28221|Deltaproteobacteria,2M8ZS@213115|Desulfovibrionales	28221|Deltaproteobacteria	H	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	queA	GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
k141_4433_1	1121396.KB893077_gene732	6.31e-182	513.0	COG0330@1|root,COG0330@2|Bacteria,1R8RD@1224|Proteobacteria,42QFB@68525|delta/epsilon subdivisions,2WJQE@28221|Deltaproteobacteria,2MMN0@213118|Desulfobacterales	28221|Deltaproteobacteria	O	prohibitin homologues	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
k141_4433_2	1121396.KB893077_gene733	4.27e-178	504.0	COG0330@1|root,COG0330@2|Bacteria,1N5JY@1224|Proteobacteria,42MNX@68525|delta/epsilon subdivisions,2WK2W@28221|Deltaproteobacteria,2MMS8@213118|Desulfobacterales	28221|Deltaproteobacteria	O	prohibitin homologues	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
k141_4433_3	96561.Dole_2320	9.38e-18	78.6	294U0@1|root,2ZS77@2|Bacteria,1PBP0@1224|Proteobacteria,4329Q@68525|delta/epsilon subdivisions,2WY84@28221|Deltaproteobacteria,2MP66@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_4433_4	1232437.KL662048_gene5106	2.54e-32	114.0	2DNSE@1|root,32YX0@2|Bacteria,1NDIN@1224|Proteobacteria,42W7Y@68525|delta/epsilon subdivisions,2WS1U@28221|Deltaproteobacteria,2MKWT@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_1026_1	709991.Odosp_3305	1.02e-20	95.9	COG0770@1|root,COG0787@1|root,COG0770@2|Bacteria,COG0787@2|Bacteria,4NEXM@976|Bacteroidetes,2FMM3@200643|Bacteroidia,22WCC@171551|Porphyromonadaceae	976|Bacteroidetes	M	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	alr	-	5.1.1.1,6.3.2.10	ko:K01775,ko:K01929	ko00300,ko00473,ko00550,ko01100,ko01502,map00300,map00473,map00550,map01100,map01502	-	R00401,R04573,R04617	RC00064,RC00141,RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N,Mur_ligase,Mur_ligase_M
k141_689_1	1265505.ATUG01000003_gene604	1.09e-115	360.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2WJVV@28221|Deltaproteobacteria,2MI7E@213118|Desulfobacterales	28221|Deltaproteobacteria	V	Hydrophobe Amphiphile Efflux-1 (HAE1) Family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
k141_5115_1	1348635.BBJY01000004_gene3103	1.07e-248	693.0	COG1502@1|root,COG1502@2|Bacteria,1MWUW@1224|Proteobacteria,1RPQG@1236|Gammaproteobacteria,1XTMF@135623|Vibrionales	135623|Vibrionales	I	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol	cls	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2,PLDc_N
k141_5115_2	1280001.BAOA01000078_gene3147	6.26e-51	172.0	COG0626@1|root,COG0626@2|Bacteria,1MU9E@1224|Proteobacteria,1RQI0@1236|Gammaproteobacteria,1XSKH@135623|Vibrionales	135623|Vibrionales	E	COG0626 Cystathionine beta-lyases cystathionine gamma-synthases	metC	-	4.4.1.8	ko:K01760	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	M00017	R00782,R01286,R02408,R04941	RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303	ko00000,ko00001,ko00002,ko01000	-	-	-	Cys_Met_Meta_PP
k141_1027_1	644282.Deba_3272	4.72e-113	340.0	COG0427@1|root,COG0427@2|Bacteria,1MUGE@1224|Proteobacteria,42MHC@68525|delta/epsilon subdivisions,2WINZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	acetyl-CoA hydrolase transferase	-	-	-	-	-	-	-	-	-	-	-	iAF987.Gmet_3304	AcetylCoA_hyd_C,AcetylCoA_hydro,Acetyltransf_1
k141_3072_1	448385.sce0007	2.57e-16	80.5	COG0735@1|root,COG0735@2|Bacteria,1RDWJ@1224|Proteobacteria,42MN8@68525|delta/epsilon subdivisions,2WQKR@28221|Deltaproteobacteria,2YVE5@29|Myxococcales	28221|Deltaproteobacteria	K	Belongs to the Fur family	fur	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
k141_3072_2	96561.Dole_2214	2.52e-22	96.7	COG0326@1|root,COG0326@2|Bacteria,1MUUE@1224|Proteobacteria,42N42@68525|delta/epsilon subdivisions,2WK62@28221|Deltaproteobacteria,2MI73@213118|Desulfobacterales	28221|Deltaproteobacteria	O	Molecular chaperone. Has ATPase activity	htpG	-	-	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	-	-	-	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	-	-	-	HATPase_c,HATPase_c_3,HSP90
k141_4434_2	384676.PSEEN1997	1.8e-23	106.0	COG0210@1|root,COG0514@1|root,COG0210@2|Bacteria,COG0514@2|Bacteria,1MVGG@1224|Proteobacteria,1RMPG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	DNA helicase	-	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,UvrD-helicase,UvrD_C
k141_344_1	1188252.AJYK01000022_gene1409	9.93e-45	150.0	COG0724@1|root,COG0724@2|Bacteria,1N0P8@1224|Proteobacteria,1S987@1236|Gammaproteobacteria,1XWU8@135623|Vibrionales	135623|Vibrionales	S	COG0724 RNA-binding proteins (RRM domain)	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
k141_344_2	675815.VOA_002890	8.35e-90	274.0	COG0796@1|root,COG0796@2|Bacteria,1NAI2@1224|Proteobacteria,1RPU9@1236|Gammaproteobacteria,1XTNA@135623|Vibrionales	135623|Vibrionales	M	Provides the (R)-glutamate required for cell wall biosynthesis	murI	GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008881,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016853,GO:0016854,GO:0016855,GO:0030203,GO:0034645,GO:0036361,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0047661,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	5.1.1.3	ko:K01776	ko00471,ko01100,map00471,map01100	-	R00260	RC00302	ko00000,ko00001,ko01000,ko01011	-	-	-	Asp_Glu_race
k141_344_3	675806.VII_003744	1.4e-179	529.0	COG4206@1|root,COG4206@2|Bacteria,1MW63@1224|Proteobacteria,1RMFJ@1236|Gammaproteobacteria,1XT6V@135623|Vibrionales	135623|Vibrionales	H	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB	btuB	GO:0003674,GO:0005215	-	ko:K16092	-	-	-	-	ko00000,ko02000	1.B.14.3	-	-	Plug,TonB_dep_Rec
k141_344_4	223926.28807965	5.89e-216	602.0	COG2265@1|root,COG2265@2|Bacteria,1MY45@1224|Proteobacteria,1RN2B@1236|Gammaproteobacteria,1XSB1@135623|Vibrionales	135623|Vibrionales	J	Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA)	trmA	GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360	2.1.1.35	ko:K00557	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA_U5-meth_tr
k141_344_6	1517681.HW45_18720	2.51e-111	325.0	COG1309@1|root,COG1309@2|Bacteria,1MUJ5@1224|Proteobacteria,1RN9W@1236|Gammaproteobacteria,1XUMQ@135623|Vibrionales	135623|Vibrionales	K	Transcriptional regulator	fabR	-	-	ko:K22105	-	-	-	-	ko00000,ko03000	-	-	-	TetR_N
k141_344_8	520999.PROVALCAL_01629	1.39e-42	143.0	COG0818@1|root,COG0818@2|Bacteria,1MZ3Q@1224|Proteobacteria,1S92I@1236|Gammaproteobacteria,3Z92Q@586|Providencia	1236|Gammaproteobacteria	M	Recycling of diacylglycerol produced during the turnover of membrane phospholipid	dgkA	GO:0003674,GO:0003824,GO:0004143,GO:0005575,GO:0005623,GO:0005886,GO:0006629,GO:0006644,GO:0006650,GO:0006654,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0045017,GO:0046473,GO:0046474,GO:0046486,GO:0050896,GO:0071704,GO:0071944,GO:0090407,GO:1901576	2.7.1.107	ko:K00901	ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00561,map00564,map01100,map01110,map04070,map04072,map05231	-	R02240	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	DAGK_prokar
k141_344_9	675814.VIC_000186	0.0	959.0	COG2937@1|root,COG2937@2|Bacteria,1MWZ6@1224|Proteobacteria,1RM7K@1236|Gammaproteobacteria,1XUC5@135623|Vibrionales	135623|Vibrionales	I	Belongs to the GPAT DAPAT family	plsB	GO:0003674,GO:0003824,GO:0004366,GO:0006629,GO:0006644,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008374,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0071704,GO:0090407,GO:1901576	2.3.1.15	ko:K00631	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
k141_344_10	1219076.N646_2044	3.35e-150	428.0	COG0382@1|root,COG0382@2|Bacteria,1MV4Q@1224|Proteobacteria,1RMZ1@1236|Gammaproteobacteria,1XT4I@135623|Vibrionales	135623|Vibrionales	H	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate	ubiA	GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008412,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016765,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663	2.5.1.39	ko:K03179	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R05000,R05615	RC00209,RC02895	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
k141_344_11	1225785.CM001983_gene529	1.85e-32	121.0	COG3161@1|root,COG3161@2|Bacteria,1RC9M@1224|Proteobacteria,1T0TE@1236|Gammaproteobacteria	1236|Gammaproteobacteria	H	Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway	ubiC	-	4.1.3.40	ko:K03181	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R01302	RC00491,RC02148	ko00000,ko00001,ko00002,ko01000	-	-	-	Chor_lyase
k141_4774_2	880073.Calab_2615	1.01e-27	125.0	COG0840@1|root,COG0840@2|Bacteria,2NQS9@2323|unclassified Bacteria	2|Bacteria	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal,dCache_1,sCache_2
k141_4774_3	1198452.Jab_2c12100	1.66e-21	91.7	COG4564@1|root,COG4564@2|Bacteria,1N7NM@1224|Proteobacteria,2WC5Y@28216|Betaproteobacteria,4771Q@75682|Oxalobacteraceae	28216|Betaproteobacteria	T	Single Cache domain 2	-	-	-	-	-	-	-	-	-	-	-	-	sCache_2
k141_1030_1	1232437.KL662061_gene4132	2.89e-43	155.0	COG0507@1|root,COG0514@1|root,COG0507@2|Bacteria,COG0514@2|Bacteria,1QCFP@1224|Proteobacteria,42NH5@68525|delta/epsilon subdivisions,2WKAR@28221|Deltaproteobacteria,2MHPD@213118|Desulfobacterales	28221|Deltaproteobacteria	L	Helix-turn-helix domain	-	-	3.6.4.12	ko:K15255	-	-	-	-	ko00000,ko01000,ko03029,ko03032	-	-	-	HRDC,HTH_40,Herpes_Helicase,PIF1
k141_4435_1	744872.Spica_1836	1.02e-34	121.0	COG2033@1|root,COG2033@2|Bacteria,2J8F0@203691|Spirochaetes	203691|Spirochaetes	C	Desulfoferrodoxin ferrous iron-binding domain	-	-	1.15.1.2	ko:K05919	-	-	-	-	ko00000,ko01000	-	-	-	Desulfoferrod_N,Desulfoferrodox
k141_4435_2	1123371.ATXH01000008_gene246	1.89e-66	207.0	COG1528@1|root,COG1528@2|Bacteria,2GGRA@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	P	Ferritin-like domain	-	-	1.16.3.2	ko:K02217	-	-	-	-	ko00000,ko01000	-	-	-	Ferritin
k141_4435_3	644282.Deba_1631	3.41e-23	89.4	COG1592@1|root,COG1592@2|Bacteria,1NIX3@1224|Proteobacteria,42XNR@68525|delta/epsilon subdivisions,2WSUH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Rubrerythrin	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_345_1	1249627.D779_3181	3.01e-98	298.0	28IBE@1|root,2Z8DX@2|Bacteria,1NC7D@1224|Proteobacteria,1RP6N@1236|Gammaproteobacteria,1WX33@135613|Chromatiales	135613|Chromatiales	S	Putative amidoligase enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Amidoligase_2
k141_4775_1	1304885.AUEY01000005_gene871	2.63e-157	459.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,42M5F@68525|delta/epsilon subdivisions,2WJN6@28221|Deltaproteobacteria,2MIDA@213118|Desulfobacterales	28221|Deltaproteobacteria	IQ	PFAM AMP-dependent synthetase and ligase	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
k141_16_1	179408.Osc7112_5096	4.83e-38	152.0	COG0515@1|root,COG0745@1|root,COG2203@1|root,COG3899@1|root,COG5002@1|root,COG0515@2|Bacteria,COG0745@2|Bacteria,COG2203@2|Bacteria,COG3899@2|Bacteria,COG5002@2|Bacteria,1GBKM@1117|Cyanobacteria,1H7D9@1150|Oscillatoriales	1117|Cyanobacteria	KLT	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GAF,HATPase_c,HisKA,PAS_3,Pkinase,Response_reg
k141_1031_1	314292.VAS14_14329	8.25e-139	402.0	COG1477@1|root,COG1477@2|Bacteria,1MW6K@1224|Proteobacteria,1RNMZ@1236|Gammaproteobacteria,1XW9Z@135623|Vibrionales	135623|Vibrionales	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	-	-	-	-	-	-	-	-	-	-	-	-	ApbE
k141_1706_1	1348635.BBJY01000009_gene1457	0.0	969.0	COG1866@1|root,COG1866@2|Bacteria,1MWXN@1224|Proteobacteria,1RPM0@1236|Gammaproteobacteria,1XT8R@135623|Vibrionales	135623|Vibrionales	F	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA	pckA	GO:0003674,GO:0003824,GO:0004611,GO:0004612,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0008150,GO:0008152,GO:0009058,GO:0016051,GO:0016829,GO:0016830,GO:0016831,GO:0019318,GO:0019319,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0071704,GO:1901576	4.1.1.49	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00170	R00341	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPCK_ATP
k141_1706_2	55601.VANGNB10_cI0150c	5.48e-103	333.0	COG2911@1|root,COG2911@2|Bacteria,1QUFI@1224|Proteobacteria,1T1X6@1236|Gammaproteobacteria,1XU6R@135623|Vibrionales	135623|Vibrionales	S	AsmA family	-	-	-	-	-	-	-	-	-	-	-	-	AsmA
k141_1706_3	243277.VC_2740	2.33e-182	511.0	COG0454@1|root,COG2050@1|root,COG0456@2|Bacteria,COG2050@2|Bacteria,1QU0P@1224|Proteobacteria,1T1K4@1236|Gammaproteobacteria,1Y33T@135623|Vibrionales	135623|Vibrionales	KQ	Putative thioesterase (yiiD_Cterm)	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_10,YiiD_C
k141_1706_4	1219080.VEZ01S_37_00710	3.32e-79	237.0	COG1490@1|root,COG1490@2|Bacteria,1RGTV@1224|Proteobacteria,1S61I@1236|Gammaproteobacteria,1XWX3@135623|Vibrionales	135623|Vibrionales	J	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality	dtd	GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360	-	ko:K07560	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Tyr_Deacylase
k141_1706_5	29495.EA26_01375	4.13e-125	367.0	COG1295@1|root,COG1295@2|Bacteria,1QICW@1224|Proteobacteria,1RMKI@1236|Gammaproteobacteria,1XUTA@135623|Vibrionales	135623|Vibrionales	S	membrane	rbn	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
k141_1706_6	223926.28805106	2.43e-57	185.0	28NM7@1|root,2ZBMT@2|Bacteria,1R9Y9@1224|Proteobacteria,1S227@1236|Gammaproteobacteria,1XSXZ@135623|Vibrionales	135623|Vibrionales	S	Protein of unknown function (DUF2959)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2959
k141_4182_4	1232683.ADIMK_3032	1.12e-135	395.0	COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,1RYR9@1236|Gammaproteobacteria,468UK@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
k141_4182_5	948565.AFFP02000032_gene1566	4.88e-16	82.4	COG1404@1|root,COG2931@1|root,COG4935@1|root,COG1404@2|Bacteria,COG2931@2|Bacteria,COG4935@2|Bacteria,1MU7T@1224|Proteobacteria,1T2VQ@1236|Gammaproteobacteria,1YAU9@135625|Pasteurellales	135625|Pasteurellales	OQ	Haemolysin-type calcium binding protein related domain	avxIA	-	-	-	-	-	-	-	-	-	-	-	HCBP_related,HemolysinCabind,P_proprotein,Peptidase_S8
k141_198_1	644801.Psest_2400	4.5e-65	218.0	COG2907@1|root,COG2907@2|Bacteria,1MV4Z@1224|Proteobacteria,1RP4P@1236|Gammaproteobacteria,1Z0UQ@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	S	Amine oxidase	-	-	-	ko:K06954	-	-	-	-	ko00000	-	-	-	Amino_oxidase,NAD_binding_8
k141_198_2	744979.R2A130_0967	4.12e-15	79.7	COG3496@1|root,COG3496@2|Bacteria,1RC56@1224|Proteobacteria,2TUX0@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Protein of unknown function (DUF1365)	-	-	-	ko:K09701	-	-	-	-	ko00000	-	-	-	DUF1365
k141_3187_1	1116375.VEJY3_05825	4.39e-29	105.0	COG3313@1|root,COG3313@2|Bacteria,1NGD5@1224|Proteobacteria,1SCBM@1236|Gammaproteobacteria,1XYE2@135623|Vibrionales	135623|Vibrionales	S	Fe-S protein	-	-	-	ko:K06938	-	-	-	-	ko00000	-	-	-	DUF1289
k141_3858_3	999411.HMPREF1092_01510	2.41e-105	313.0	COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia,36ED6@31979|Clostridiaceae	186801|Clostridia	N	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella	fliC	-	-	ko:K02406	ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flagellin_C,Flagellin_N
k141_3858_4	1230342.CTM_08366	4.95e-137	422.0	COG2604@1|root,COG2604@2|Bacteria,1U2BC@1239|Firmicutes,24CSU@186801|Clostridia,36G68@31979|Clostridiaceae	186801|Clostridia	S	Protein of unknown function DUF115	-	-	-	-	-	-	-	-	-	-	-	-	MAF_flag10
k141_3858_5	439235.Dalk_0647	5.29e-06	50.1	COG1334@1|root,COG1334@2|Bacteria	2|Bacteria	N	flagellar protein FlaG	flaG	-	-	ko:K06603	-	-	-	-	ko00000,ko02035	-	-	-	FlaG
k141_3858_6	1121324.CLIT_13c00940	3.67e-124	382.0	COG1345@1|root,COG1345@2|Bacteria,1TQ66@1239|Firmicutes,248Q9@186801|Clostridia,25SRV@186804|Peptostreptococcaceae	186801|Clostridia	N	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end	fliD	-	-	ko:K02407	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flagellin_IN,FliD_C,FliD_N
k141_3858_7	1286171.EAL2_c03470	2.22e-55	176.0	COG1516@1|root,COG1516@2|Bacteria,1VA8K@1239|Firmicutes,24MRW@186801|Clostridia,25X2K@186806|Eubacteriaceae	186801|Clostridia	N	Flagellar protein FliS	fliS	-	-	ko:K02422	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliS
k141_3858_9	913865.DOT_5370	6.01e-09	53.9	2DR71@1|root,33AGR@2|Bacteria,1VKHI@1239|Firmicutes,25IF8@186801|Clostridia,266P5@186807|Peptococcaceae	186801|Clostridia	S	Putative motility protein	-	-	-	-	-	-	-	-	-	-	-	-	YjfB_motility
k141_3858_11	1443122.Z958_08245	1.63e-59	206.0	COG2604@1|root,COG2604@2|Bacteria,1V4NE@1239|Firmicutes,24CPP@186801|Clostridia,36GUD@31979|Clostridiaceae	186801|Clostridia	S	Protein of unknown function DUF115	-	-	-	-	-	-	-	-	-	-	-	-	MAF_flag10
k141_3858_13	1511.CLOST_2321	4.96e-75	242.0	COG1527@1|root,COG1527@2|Bacteria,1U1QE@1239|Firmicutes,24A4E@186801|Clostridia,25RRC@186804|Peptostreptococcaceae	186801|Clostridia	C	ATP synthase (C/AC39) subunit	ntpC	-	-	ko:K02119	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	vATP-synt_AC39
k141_3858_14	1286171.EAL2_c03510	1.11e-150	458.0	COG1269@1|root,COG1269@2|Bacteria,1TPTE@1239|Firmicutes,249YV@186801|Clostridia,25W06@186806|Eubacteriaceae	186801|Clostridia	U	V-type ATPase 116kDa subunit family	ntpI	-	-	ko:K02123	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	V_ATPase_I
k141_3858_15	1304284.L21TH_0591	2.69e-38	134.0	COG0636@1|root,COG0636@2|Bacteria,1VAGE@1239|Firmicutes,24RB6@186801|Clostridia,36K54@31979|Clostridiaceae	186801|Clostridia	C	ATP synthase, subunit C	-	-	-	ko:K02124	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_C
k141_3858_16	1511.CLOST_2318	7.02e-34	119.0	COG1436@1|root,COG1436@2|Bacteria,1VEN1@1239|Firmicutes,24K2E@186801|Clostridia,25RXM@186804|Peptostreptococcaceae	186801|Clostridia	C	ATP synthase (F/14-kDa) subunit	-	-	-	ko:K02122	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_F
k141_3858_18	1121324.CLIT_13c01040	4.4e-282	788.0	COG1155@1|root,COG1155@2|Bacteria,1TPGS@1239|Firmicutes,24882@186801|Clostridia,25QTT@186804|Peptostreptococcaceae	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit	ntpA	-	3.6.3.14,3.6.3.15	ko:K02117	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002,ko01000	3.A.2.2,3.A.2.3	-	-	ATP-synt_ab,ATP-synt_ab_N,ATP-synt_ab_Xtn
k141_3858_19	1304284.L21TH_0587	5.29e-232	650.0	COG1156@1|root,COG1156@2|Bacteria,1VSU1@1239|Firmicutes,2496H@186801|Clostridia,36DRP@31979|Clostridiaceae	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit	ntpB	-	-	ko:K02118	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_ab,ATP-synt_ab_N
k141_3858_20	857293.CAAU_1875	5.2e-66	209.0	COG1394@1|root,COG1394@2|Bacteria,1TQ4P@1239|Firmicutes,24Z7J@186801|Clostridia,36WU0@31979|Clostridiaceae	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpD	-	-	ko:K02120	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_D
k141_3858_21	1511.CLOST_2313	7.1e-61	193.0	COG1544@1|root,COG1544@2|Bacteria,1V1D5@1239|Firmicutes,24HDH@186801|Clostridia,25RKK@186804|Peptostreptococcaceae	186801|Clostridia	J	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase	hpf	-	-	ko:K05808	-	-	-	-	ko00000,ko03009	-	-	-	Ribosom_S30AE_C,Ribosomal_S30AE
k141_3858_22	65093.PCC7418_3088	3.14e-95	303.0	COG1249@1|root,COG1249@2|Bacteria,1G198@1117|Cyanobacteria	1117|Cyanobacteria	C	Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Pyr_redox_dim
k141_3858_24	941824.TCEL_01644	1.56e-142	410.0	COG1210@1|root,COG1210@2|Bacteria,1TQ24@1239|Firmicutes,25E5A@186801|Clostridia,36EIH@31979|Clostridiaceae	186801|Clostridia	M	UTP-glucose-1-phosphate uridylyltransferase	galU	-	2.7.7.9	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	M00129,M00361,M00362,M00549	R00289	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS02205	NTP_transferase
k141_2808_1	675815.VOA_000646	1.3e-265	741.0	COG1226@1|root,COG4651@1|root,COG1226@2|Bacteria,COG4651@2|Bacteria,1MV34@1224|Proteobacteria,1RNH4@1236|Gammaproteobacteria,1XV3J@135623|Vibrionales	135623|Vibrionales	P	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger,TrkA_N
k141_200_2	1304885.AUEY01000158_gene3675	7.29e-15	75.1	COG1247@1|root,COG1247@2|Bacteria,1N04H@1224|Proteobacteria	1224|Proteobacteria	M	YoaP-like	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,YoaP
k141_3537_2	1517681.HW45_28900	3.38e-26	106.0	COG0577@1|root,COG0577@2|Bacteria,1R75G@1224|Proteobacteria,1S0QT@1236|Gammaproteobacteria	1236|Gammaproteobacteria	V	MacB-like periplasmic core domain	lolE_1	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
k141_3537_3	1517681.HW45_28875	1.45e-57	199.0	COG0672@1|root,COG0672@2|Bacteria,1MXHM@1224|Proteobacteria,1RMWB@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	Iron Permease	efeU_1	-	-	ko:K07243	-	-	-	-	ko00000,ko02000	2.A.108.1,2.A.108.2	-	-	Cytochrome_CBB3,FTR1
k141_2810_1	572544.Ilyop_1225	3.8e-05	45.4	COG0841@1|root,COG0841@2|Bacteria,378MK@32066|Fusobacteria	32066|Fusobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k141_3188_1	583355.Caka_2713	7.76e-27	123.0	COG4782@1|root,COG4782@2|Bacteria	2|Bacteria	P	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF900
k141_2448_1	1121451.DESAM_20098	1.89e-56	180.0	COG0716@1|root,COG0716@2|Bacteria,1MX7F@1224|Proteobacteria,42Q5G@68525|delta/epsilon subdivisions,2WPZ8@28221|Deltaproteobacteria,2MBXP@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	PFAM flavodoxin nitric oxide synthase	-	-	-	ko:K03839	-	-	-	-	ko00000	-	-	-	Flavodoxin_1
k141_2448_3	983545.Glaag_0123	1.09e-147	426.0	COG3621@1|root,COG3621@2|Bacteria,1RDY7@1224|Proteobacteria,1RSC7@1236|Gammaproteobacteria,468TT@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Patatin-like phospholipase	-	-	-	ko:K06900	-	-	-	-	ko00000	-	-	-	Patatin
k141_3189_1	906968.Trebr_1757	5.02e-13	72.4	COG0250@1|root,COG0250@2|Bacteria,2J829@203691|Spirochaetes	203691|Spirochaetes	K	Transcription antitermination protein, NusG	-	-	-	ko:K02601	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusG
k141_4183_1	926567.TheveDRAFT_1808	3.37e-23	103.0	COG2199@1|root,COG2199@2|Bacteria,3TC60@508458|Synergistetes	508458|Synergistetes	T	PFAM GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS_9
k141_4183_2	345073.VC395_1831	2.24e-310	897.0	COG3096@1|root,COG3096@2|Bacteria,1MUWM@1224|Proteobacteria,1RPFF@1236|Gammaproteobacteria,1XUHB@135623|Vibrionales	135623|Vibrionales	D	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division	mukB	GO:0007059,GO:0008150,GO:0009987	-	ko:K03632	-	-	-	-	ko00000,ko03036	-	-	-	MukB,MukB_hinge,SbcCD_C
k141_1179_1	870967.VIS19158_02550	1.45e-82	253.0	2CCQ9@1|root,2Z7HY@2|Bacteria,1MUWR@1224|Proteobacteria,1RPKI@1236|Gammaproteobacteria,1XVEW@135623|Vibrionales	135623|Vibrionales	S	Phage major capsid protein, P2 family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_cap_P2
k141_1179_2	870967.VIS19158_02555	5.97e-73	222.0	2AWCW@1|root,31N8R@2|Bacteria,1QK01@1224|Proteobacteria,1TI2F@1236|Gammaproteobacteria,1XY84@135623|Vibrionales	135623|Vibrionales	S	Phage head completion protein (GPL)	-	-	-	-	-	-	-	-	-	-	-	-	Phage_GPL
k141_1179_3	1187848.AJYQ01000156_gene3818	4.57e-69	213.0	2AW96@1|root,31N4H@2|Bacteria,1QJVZ@1224|Proteobacteria,1THXM@1236|Gammaproteobacteria,1XXUG@135623|Vibrionales	135623|Vibrionales	S	P2 phage tail completion protein R (GpR)	-	-	-	-	-	-	-	-	-	-	-	-	P2_Phage_GpR
k141_1179_4	1187848.AJYQ01000156_gene3817	1.74e-84	253.0	2AW3F@1|root,31MYA@2|Bacteria,1QJQB@1224|Proteobacteria,1THRF@1236|Gammaproteobacteria,1XXAF@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Phage_tail_S
k141_1179_5	312309.VF_2640	3.95e-14	66.6	2EICU@1|root,33C46@2|Bacteria,1NGMA@1224|Proteobacteria,1SGJZ@1236|Gammaproteobacteria,1XZI9@135623|Vibrionales	135623|Vibrionales	S	Protein of unknown function (DUF2635)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2635
k141_1179_6	870967.VIS19158_02575	8.97e-227	630.0	COG4386@1|root,COG4386@2|Bacteria,1MXZD@1224|Proteobacteria,1RN4Q@1236|Gammaproteobacteria,1XWPC@135623|Vibrionales	135623|Vibrionales	S	Phage tail sheath C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Phage_sheath_1,Phage_sheath_1C
k141_1179_7	870967.VIS19158_02580	1.94e-67	206.0	2AWDJ@1|root,31N9I@2|Bacteria,1QK0Q@1224|Proteobacteria,1TI34@1236|Gammaproteobacteria,1XY9J@135623|Vibrionales	135623|Vibrionales	S	Phage tail tube protein	-	-	-	-	-	-	-	-	-	-	-	-	Tail_tube
k141_1179_8	1187848.AJYQ01000156_gene3813	5.44e-94	282.0	2AW5W@1|root,31N0W@2|Bacteria,1QJSN@1224|Proteobacteria,1THTX@1236|Gammaproteobacteria,1XXIG@135623|Vibrionales	135623|Vibrionales	S	Phage small terminase subunit	-	-	-	-	-	-	-	-	-	-	-	-	Phage_term_smal
k141_1179_9	870967.VIS19158_02590	2.7e-41	138.0	2AJFT@1|root,31A26@2|Bacteria,1QTEN@1224|Proteobacteria,1TIH5@1236|Gammaproteobacteria,1XZ47@135623|Vibrionales	135623|Vibrionales	S	Phage tail assembly chaperone proteins, E, or 41 or 14	-	-	-	-	-	-	-	-	-	-	-	-	Phage_TAC_7
k141_5179_1	617140.AJZE01000035_gene3256	1.39e-171	500.0	COG1178@1|root,COG1178@2|Bacteria,1MWCF@1224|Proteobacteria,1RNHK@1236|Gammaproteobacteria,1XT1Z@135623|Vibrionales	135623|Vibrionales	P	COG1178 ABC-type Fe3 transport system, permease component	thiP	-	-	ko:K02063	ko02010,map02010	M00191	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.19	-	-	BPD_transp_1
k141_5179_2	298386.PBPRA0411	5.67e-74	231.0	COG3840@1|root,COG3840@2|Bacteria,1MV78@1224|Proteobacteria,1RQH3@1236|Gammaproteobacteria,1XU4J@135623|Vibrionales	135623|Vibrionales	P	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system	thiQ	GO:0003674,GO:0003824,GO:0005215,GO:0006810,GO:0006855,GO:0008150,GO:0015234,GO:0015238,GO:0015399,GO:0015405,GO:0015888,GO:0015893,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0035461,GO:0042221,GO:0042493,GO:0042623,GO:0042626,GO:0043492,GO:0045117,GO:0050896,GO:0051179,GO:0051180,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071934,GO:0072348,GO:0072531,GO:0090482,GO:1901474,GO:1901682	-	ko:K02062	ko02010,map02010	M00191	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.19	-	-	ABC_tran
k141_5179_3	493475.GARC_0531	2.99e-19	90.5	2ES37@1|root,33JN3@2|Bacteria,1NPKW@1224|Proteobacteria,1SHEV@1236|Gammaproteobacteria,4691N@72275|Alteromonadaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_5179_4	319224.Sputcn32_0911	1.21e-20	86.7	2B74X@1|root,3206C@2|Bacteria,1QDHC@1224|Proteobacteria,1TBVH@1236|Gammaproteobacteria,2QD5R@267890|Shewanellaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_1855_1	1187848.AJYQ01000004_gene240	3.2e-302	847.0	COG2352@1|root,COG2352@2|Bacteria,1MUD5@1224|Proteobacteria,1RPTP@1236|Gammaproteobacteria,1XUG5@135623|Vibrionales	135623|Vibrionales	H	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle	ppc	GO:0003674,GO:0003824,GO:0004611,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0008964,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016830,GO:0016831,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0055114,GO:0071704,GO:0072350	4.1.1.31	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	M00168,M00170,M00171,M00172,M00173,M00346,M00374	R00345	RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPcase
k141_1855_2	675815.VOA_003488	1.54e-225	627.0	COG0624@1|root,COG0624@2|Bacteria,1MVBR@1224|Proteobacteria,1RNDG@1236|Gammaproteobacteria,1XVA2@135623|Vibrionales	135623|Vibrionales	E	Belongs to the peptidase M20A family. ArgE subfamily	argE	GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008777,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016787,GO:0016810,GO:0016811,GO:0019213,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	3.5.1.16	ko:K01438	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R00669,R09107	RC00064,RC00300	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20
k141_1855_3	223926.28807769	3.12e-198	554.0	COG0002@1|root,COG0002@2|Bacteria,1MVJ6@1224|Proteobacteria,1RNMX@1236|Gammaproteobacteria,1XSZ0@135623|Vibrionales	135623|Vibrionales	E	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde	argC	GO:0003674,GO:0003824,GO:0003942,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.2.1.38	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R03443	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
k141_1855_4	675813.VIB_000499	1.7e-120	351.0	COG0548@1|root,COG0548@2|Bacteria,1MU17@1224|Proteobacteria,1RNKK@1236|Gammaproteobacteria,1XSF2@135623|Vibrionales	135623|Vibrionales	F	Belongs to the acetylglutamate kinase family. ArgB subfamily	argB	GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.2.8	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R02649	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
k141_1855_5	1188252.AJYK01000068_gene232	2.07e-266	733.0	COG0137@1|root,COG0137@2|Bacteria,1MV0Y@1224|Proteobacteria,1RMEC@1236|Gammaproteobacteria,1XU2D@135623|Vibrionales	135623|Vibrionales	F	Belongs to the argininosuccinate synthase family. Type 1 subfamily	argG	GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Arginosuc_synth
k141_1855_6	29495.EA26_02370	0.0	1114.0	COG0165@1|root,COG1246@1|root,COG0165@2|Bacteria,COG1246@2|Bacteria,1MUTU@1224|Proteobacteria,1RMA3@1236|Gammaproteobacteria,1XSAT@135623|Vibrionales	135623|Vibrionales	E	belongs to the lyase 1 family. Argininosuccinate lyase subfamily	argH	GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.3.1.1,4.3.2.1	ko:K14681	ko00220,ko00250,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map01100,map01110,map01130,map01210,map01230	M00028,M00029,M00844	R00259,R01086	RC00004,RC00064,RC00445,RC00447	ko00000,ko00001,ko00002,ko01000	-	-	-	ASL_C2,Acetyltransf_1,Lyase_1
k141_1855_7	675815.VOA_003483	7.61e-33	115.0	2AWQW@1|root,31NMU@2|Bacteria,1QKCD@1224|Proteobacteria,1TIFW@1236|Gammaproteobacteria,1XZ23@135623|Vibrionales	135623|Vibrionales	S	Protein of unknown function (DUF3624)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3624
k141_1855_8	55601.VANGNB10_cI2391	5.81e-162	454.0	COG0678@1|root,COG0695@1|root,COG0678@2|Bacteria,COG0695@2|Bacteria,1MU0H@1224|Proteobacteria,1RRFB@1236|Gammaproteobacteria,1XSPT@135623|Vibrionales	135623|Vibrionales	O	Peroxiredoxin family protein glutaredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Glutaredoxin,Redoxin
k141_1855_9	1219076.N646_1846	3.13e-173	488.0	COG0583@1|root,COG0583@2|Bacteria,1MVA1@1224|Proteobacteria,1RPAJ@1236|Gammaproteobacteria,1XSJB@135623|Vibrionales	135623|Vibrionales	K	COG0583 Transcriptional regulator	oxyR	-	-	ko:K04761	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_1,LysR_substrate
k141_1855_10	675815.VOA_003479	0.0	1192.0	COG5009@1|root,COG5009@2|Bacteria,1MU5A@1224|Proteobacteria,1RM7J@1236|Gammaproteobacteria,1XT2B@135623|Vibrionales	135623|Vibrionales	M	COG5009 Membrane carboxypeptidase penicillin-binding protein	mrcA	GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	PCB_OB,Transgly,Transpeptidase
k141_1855_14	55601.VANGNB10_cI2384c	1.04e-108	337.0	COG4796@1|root,COG4796@2|Bacteria,1QTT6@1224|Proteobacteria,1RN3Z@1236|Gammaproteobacteria,1XSBC@135623|Vibrionales	135623|Vibrionales	U	COG4796 Type II secretory pathway, component HofQ	pilQ	-	-	ko:K02666	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	STN,Secretin,Secretin_N
k141_1855_15	945543.VIBR0546_16663	4.14e-107	310.0	COG0703@1|root,COG0703@2|Bacteria,1MUFJ@1224|Proteobacteria,1RPF6@1236|Gammaproteobacteria,1XTR6@135623|Vibrionales	135623|Vibrionales	F	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate	aroK	GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615	2.7.1.71	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	SKI
k141_1855_16	55601.VANGNB10_cI2382c	8.42e-215	598.0	COG0337@1|root,COG0337@2|Bacteria,1MUBK@1224|Proteobacteria,1RN4I@1236|Gammaproteobacteria,1XU0D@135623|Vibrionales	135623|Vibrionales	E	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	GO:0003674,GO:0003824,GO:0003856,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576	4.2.3.4	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03083	RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase
k141_1855_17	1348635.BBJY01000009_gene1565	1.42e-154	457.0	COG3266@1|root,COG3267@1|root,COG3266@2|Bacteria,COG3267@2|Bacteria,1Q1YI@1224|Proteobacteria,1S965@1236|Gammaproteobacteria,1XSV9@135623|Vibrionales	135623|Vibrionales	U	AAA domain	VP2743	-	-	ko:K03112	-	-	-	-	ko00000	-	-	-	AAA_22,SPOR
k141_3859_1	1121918.ARWE01000001_gene3041	2.69e-35	124.0	COG2010@1|root,COG2010@2|Bacteria,1NKKK@1224|Proteobacteria,42UAC@68525|delta/epsilon subdivisions,2WXVI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Haem-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Haem_bd
k141_3859_2	1410638.JHXJ01000001_gene1796	4e-10	63.2	COG1670@1|root,COG1670@2|Bacteria,1V5XV@1239|Firmicutes,24IQA@186801|Clostridia,3WRQD@541000|Ruminococcaceae	186801|Clostridia	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
k141_3859_3	1121403.AUCV01000003_gene1675	5.51e-115	335.0	COG1028@1|root,COG1028@2|Bacteria,1R5DB@1224|Proteobacteria,42ZCM@68525|delta/epsilon subdivisions,2WU8H@28221|Deltaproteobacteria,2MMYY@213118|Desulfobacterales	28221|Deltaproteobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
k141_3859_4	1227276.HMPREF9148_01833	8.03e-15	84.3	COG1233@1|root,COG1233@2|Bacteria,4NG5Y@976|Bacteroidetes,2FM9Y@200643|Bacteroidia	976|Bacteroidetes	Q	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase,NAD_binding_8
k141_1180_1	1408324.JNJK01000051_gene3734	1.52e-29	121.0	COG0507@1|root,COG0507@2|Bacteria,1UXF1@1239|Firmicutes,25MIE@186801|Clostridia,27R8J@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Viral (Superfamily 1) RNA helicase	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_2449_1	1118054.CAGW01000082_gene3042	3.96e-11	72.4	COG2936@1|root,COG2936@2|Bacteria,1TT0H@1239|Firmicutes,4HC37@91061|Bacilli,26TMF@186822|Paenibacillaceae	91061|Bacilli	S	X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain	-	-	-	ko:K06978	-	-	-	-	ko00000	-	-	-	PepX_C,Peptidase_S15
k141_3191_2	1540257.JQMW01000011_gene1572	5.68e-10	62.8	COG0758@1|root,COG0758@2|Bacteria,1TPP7@1239|Firmicutes,24AS2@186801|Clostridia,36HEJ@31979|Clostridiaceae	186801|Clostridia	L	DNA recombination-mediator protein A	-	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A,HHH_5
k141_3860_1	1229487.AMYW01000044_gene1315	4.03e-20	94.4	COG1020@1|root,COG1020@2|Bacteria,4NDV5@976|Bacteroidetes,1HXHR@117743|Flavobacteriia,2NW64@237|Flavobacterium	976|Bacteroidetes	Q	Pfam:HxxPF_rpt	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,Methyltransf_12,PP-binding
k141_2811_2	1219065.VPR01S_09_01470	1.86e-106	311.0	COG1309@1|root,COG1309@2|Bacteria,1N3KN@1224|Proteobacteria,1SA7U@1236|Gammaproteobacteria,1XV8I@135623|Vibrionales	135623|Vibrionales	K	Transcriptional regulator	luxR	-	-	ko:K10913	ko02020,ko02024,ko05111,map02020,map02024,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	TetR_N
k141_2811_3	945550.VISI1226_02225	9.28e-106	307.0	COG0634@1|root,COG0634@2|Bacteria,1NRT8@1224|Proteobacteria,1RNPQ@1236|Gammaproteobacteria,1XT05@135623|Vibrionales	135623|Vibrionales	F	Belongs to the purine pyrimidine phosphoribosyltransferase family	hpt	-	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
k141_1869_2	298386.PBPRA0460	2.98e-176	501.0	COG1609@1|root,COG4977@1|root,COG1609@2|Bacteria,COG4977@2|Bacteria,1NYTD@1224|Proteobacteria,1RNGZ@1236|Gammaproteobacteria,1XX8F@135623|Vibrionales	135623|Vibrionales	K	helix_turn_helix, arabinose operon control protein	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	HTH_18,Peripla_BP_3
k141_1869_3	298386.PBPRA0458	1.34e-245	684.0	COG2211@1|root,COG2211@2|Bacteria,1MVUM@1224|Proteobacteria,1RP5J@1236|Gammaproteobacteria,1XT0V@135623|Vibrionales	135623|Vibrionales	G	COG2211 Na melibiose symporter and related transporters	-	-	-	ko:K03292,ko:K11104	-	-	-	-	ko00000,ko02000	2.A.2,2.A.2.1	-	-	MFS_2
k141_1869_4	395964.KE386496_gene587	5.93e-26	106.0	COG0247@1|root,COG0247@2|Bacteria,1QV1F@1224|Proteobacteria,2TWHJ@28211|Alphaproteobacteria,3NAHU@45404|Beijerinckiaceae	28211|Alphaproteobacteria	C	4Fe-4S dicluster domain	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Fer4_17,Fer4_8
k141_1869_5	1144319.PMI16_04022	2.93e-08	55.8	COG0247@1|root,COG0277@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,1MU6Y@1224|Proteobacteria,2VHCG@28216|Betaproteobacteria,472I0@75682|Oxalobacteraceae	28216|Betaproteobacteria	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	CCG,FAD-oxidase_C,FAD_binding_4,Fer4_8
k141_1869_7	1116375.VEJY3_17246	3.52e-305	849.0	COG1263@1|root,COG1264@1|root,COG2190@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,COG2190@2|Bacteria,1MXEG@1224|Proteobacteria,1RNEG@1236|Gammaproteobacteria,1XXHE@135623|Vibrionales	135623|Vibrionales	G	phosphotransferase system, EIIB	-	-	-	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	M00271	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.1.2.11,4.A.1.2.2,4.A.1.2.5,4.A.1.2.6	-	-	PTS_EIIA_1,PTS_EIIB,PTS_EIIC
k141_216_1	1131462.DCF50_p1011	5.48e-26	110.0	COG2931@1|root,COG2931@2|Bacteria,1UY2D@1239|Firmicutes,249CK@186801|Clostridia,26086@186807|Peptococcaceae	186801|Clostridia	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_216_2	525146.Ddes_0151	1.5e-70	233.0	COG1249@1|root,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,42N8Y@68525|delta/epsilon subdivisions,2WIR7@28221|Deltaproteobacteria,2MG95@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain	-	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
k141_2472_1	1122207.MUS1_01100	2.18e-189	531.0	COG4608@1|root,COG4608@2|Bacteria,1NU4K@1224|Proteobacteria,1SKPD@1236|Gammaproteobacteria,1XHZ1@135619|Oceanospirillales	135619|Oceanospirillales	E	the abc transporter	-	-	-	ko:K12372	ko02010,map02010	M00324	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
k141_2819_2	754477.Q7C_1300	1.24e-22	101.0	COG1639@1|root,COG1639@2|Bacteria,1RCW6@1224|Proteobacteria,1S3XV@1236|Gammaproteobacteria,463MA@72273|Thiotrichales	72273|Thiotrichales	T	HDOD domain	-	-	-	-	-	-	-	-	-	-	-	-	HDOD
k141_3541_1	675813.VIB_000105	5.33e-68	219.0	COG1475@1|root,COG1475@2|Bacteria,1MWF4@1224|Proteobacteria,1RPM9@1236|Gammaproteobacteria,1XW08@135623|Vibrionales	135623|Vibrionales	K	ParB family	-	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParB
k141_1870_1	1129794.C427_2250	7.44e-82	249.0	COG2071@1|root,COG2071@2|Bacteria,1NV5K@1224|Proteobacteria,1T05H@1236|Gammaproteobacteria,4678V@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	glutamine amidotransferases	-	-	-	ko:K07010	-	-	-	-	ko00000,ko01002	-	-	-	Peptidase_C26
k141_3715_3	1238450.VIBNISOn1_1420007	3.83e-160	461.0	COG1879@1|root,COG1879@2|Bacteria,1NKCW@1224|Proteobacteria,1RT5N@1236|Gammaproteobacteria,1XV03@135623|Vibrionales	135623|Vibrionales	G	COG1879 ABC-type sugar transport system, periplasmic component	-	-	-	ko:K10910	ko02020,ko02024,ko05111,map02020,map02024,map05111	-	-	-	ko00000,ko00001	-	-	-	Peripla_BP_4
k141_3715_4	1249634.D781_1550	2.81e-64	202.0	COG1443@1|root,COG1443@2|Bacteria,1R9YJ@1224|Proteobacteria,1S6ZT@1236|Gammaproteobacteria,403NZ@613|Serratia	1236|Gammaproteobacteria	I	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)	idi	GO:0003674,GO:0003824,GO:0004452,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016853,GO:0016860,GO:0016863,GO:0019637,GO:0033554,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044464,GO:0046490,GO:0050896,GO:0051716,GO:0071704,GO:0090407,GO:1901576	4.1.1.33,5.3.3.2	ko:K01597,ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00095,M00096,M00364,M00365,M00366,M00367	R01121,R01123	RC00453,RC00455	ko00000,ko00001,ko00002,ko01000	-	-	iECH74115_1262.ECH74115_4179,iECIAI1_1343.ECIAI1_3008,iECO103_1326.ECO103_3464,iECSP_1301.ECSP_3858,iECs_1301.ECs3761,iEcE24377_1341.EcE24377A_3215,iG2583_1286.G2583_3542,iSFV_1184.SFV_2937,iSF_1195.SF2875,iSFxv_1172.SFxv_3153,iSSON_1240.SSON_3042,iS_1188.S3074,iZ_1308.Z4227	NUDIX
k141_3715_5	675813.VIB_002765	7.76e-155	449.0	COG0527@1|root,COG0527@2|Bacteria,1MVSI@1224|Proteobacteria,1RQ37@1236|Gammaproteobacteria,1XUVY@135623|Vibrionales	135623|Vibrionales	E	Amino acid kinase family	-	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
k141_2337_1	933262.AXAM01000079_gene2202	1.44e-133	417.0	COG0085@1|root,COG0085@2|Bacteria,1MUC4@1224|Proteobacteria,43DMZ@68525|delta/epsilon subdivisions,2WIW5@28221|Deltaproteobacteria,2MI5C@213118|Desulfobacterales	28221|Deltaproteobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
k141_2337_2	1304885.AUEY01000001_gene3251	0.0	2058.0	COG0086@1|root,COG0086@2|Bacteria,1MU3M@1224|Proteobacteria,42NAW@68525|delta/epsilon subdivisions,2WISU@28221|Deltaproteobacteria,2MIYJ@213118|Desulfobacterales	28221|Deltaproteobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	-	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
k141_4998_1	161156.JQKW01000012_gene23	4.3e-25	103.0	COG2840@1|root,COG2840@2|Bacteria,2GGYP@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	S	Smr domain	-	-	-	-	-	-	-	-	-	-	-	-	Smr
k141_4998_2	1304885.AUEY01000022_gene3418	4.24e-27	102.0	COG1550@1|root,COG1550@2|Bacteria,1N2H7@1224|Proteobacteria,42UCZ@68525|delta/epsilon subdivisions,2WR50@28221|Deltaproteobacteria,2MKM4@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF503)	-	-	-	ko:K09764	-	-	-	-	ko00000	-	-	-	DUF503
k141_3718_1	1249627.D779_2896	1.03e-07	54.3	COG1846@1|root,COG1846@2|Bacteria,1RDGK@1224|Proteobacteria,1S5DJ@1236|Gammaproteobacteria,1WYCA@135613|Chromatiales	135613|Chromatiales	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
k141_3718_2	243231.GSU2588	1.76e-42	150.0	COG1249@1|root,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,42N8Y@68525|delta/epsilon subdivisions,2WIR7@28221|Deltaproteobacteria,43SUM@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	pyridine nucleotide-disulphide oxidoreductase dimerisation region	lpdA	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
k141_3275_1	292415.Tbd_1268	6.59e-18	89.4	COG0642@1|root,COG0745@1|root,COG2198@1|root,COG3850@1|root,COG0642@2|Bacteria,COG0745@2|Bacteria,COG2198@2|Bacteria,COG3850@2|Bacteria,1NWAF@1224|Proteobacteria,2WGYE@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Histidine Phosphotransfer domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,Response_reg
k141_3275_2	573370.DMR_09590	8.72e-19	83.6	COG0745@1|root,COG0745@2|Bacteria,1N0XC@1224|Proteobacteria,42TRF@68525|delta/epsilon subdivisions,2WQDP@28221|Deltaproteobacteria,2MBQ4@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	response regulator, receiver	-	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
k141_3275_3	1313304.CALK_1870	1.48e-35	134.0	COG4191@1|root,COG4191@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
k141_4305_1	1095749.HMPREF1052_0146	3.59e-27	106.0	COG0564@1|root,COG0564@2|Bacteria,1RDAG@1224|Proteobacteria,1S406@1236|Gammaproteobacteria,1Y7BN@135625|Pasteurellales	135625|Pasteurellales	J	Pseudouridine synthase	Z012_05060	GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	5.4.99.28,5.4.99.29	ko:K06177	-	-	-	-	ko00000,ko01000,ko03009,ko03016	-	-	-	PseudoU_synth_2
k141_4305_2	316275.VSAL_I1935	4.77e-218	613.0	COG0733@1|root,COG0733@2|Bacteria,1MUZJ@1224|Proteobacteria,1RPCT@1236|Gammaproteobacteria,1XT5X@135623|Vibrionales	135623|Vibrionales	S	COG0733 Na -dependent transporters of the SNF family	yocR	-	-	ko:K03308	-	-	-	-	ko00000	2.A.22.4,2.A.22.5	-	-	SNF
k141_4305_3	379731.PST_2280	5.8e-162	491.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,1Z0P0@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	NT	Methyl-accepting chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal,dCache_1
k141_4305_4	55601.VANGNB10_cI1132c	1.12e-255	712.0	COG1502@1|root,COG1502@2|Bacteria,1MWUW@1224|Proteobacteria,1RPQG@1236|Gammaproteobacteria,1XTMF@135623|Vibrionales	135623|Vibrionales	I	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol	cls	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2,PLDc_N
k141_4305_5	223926.28806170	2e-231	644.0	COG0626@1|root,COG0626@2|Bacteria,1MU9E@1224|Proteobacteria,1RQI0@1236|Gammaproteobacteria,1XSKH@135623|Vibrionales	135623|Vibrionales	E	COG0626 Cystathionine beta-lyases cystathionine gamma-synthases	metC	-	4.4.1.8	ko:K01760	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	M00017	R00782,R01286,R02408,R04941	RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303	ko00000,ko00001,ko00002,ko01000	-	-	-	Cys_Met_Meta_PP
k141_4305_6	1051646.VITU9109_22466	1.07e-89	268.0	COG2818@1|root,COG2818@2|Bacteria,1R9X5@1224|Proteobacteria,1S25K@1236|Gammaproteobacteria,1XT91@135623|Vibrionales	135623|Vibrionales	L	COG2818 3-methyladenine DNA glycosylase	tag	-	3.2.2.20	ko:K01246	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Adenine_glyco
k141_4305_7	945543.VIBR0546_21255	1.78e-39	135.0	COG1983@1|root,COG1983@2|Bacteria,1N085@1224|Proteobacteria,1S98J@1236|Gammaproteobacteria,1XXB4@135623|Vibrionales	135623|Vibrionales	KT	phage shock protein C	pspC	-	-	ko:K03973	-	-	-	-	ko00000,ko02048,ko03000	-	-	-	PspC
k141_4305_8	1348635.BBJY01000004_gene3099	2.33e-24	94.0	2CJWQ@1|root,32YI2@2|Bacteria,1N769@1224|Proteobacteria,1SCNV@1236|Gammaproteobacteria,1XYAE@135623|Vibrionales	135623|Vibrionales	S	Phage shock protein B	pspB	-	-	ko:K03970	-	-	-	-	ko00000,ko02048	-	-	-	PspB
k141_659_4	177437.HRM2_11500	1.15e-73	234.0	COG2861@1|root,COG2861@2|Bacteria,1N3JP@1224|Proteobacteria,42RJN@68525|delta/epsilon subdivisions,2WNEI@28221|Deltaproteobacteria,2MJKY@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Divergent polysaccharide deacetylase	yibQ	-	-	ko:K09798	-	-	-	-	ko00000	-	-	-	Polysacc_deac_2
k141_4742_1	1187848.AJYQ01000090_gene2883	5.99e-108	325.0	28IW1@1|root,2Z8UB@2|Bacteria,1N1QM@1224|Proteobacteria,1T19C@1236|Gammaproteobacteria,1Y2Q2@135623|Vibrionales	135623|Vibrionales	S	F plasmid transfer operon, TraF, protein	-	-	-	-	-	-	-	-	-	-	-	-	TraF_2
k141_4743_1	1461694.ATO9_13630	9.56e-104	310.0	COG0687@1|root,COG0687@2|Bacteria,1PRWU@1224|Proteobacteria,2U2MI@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Required for the activity of the bacterial periplasmic transport system of putrescine	potD	-	-	ko:K11069	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	SBP_bac_6,SBP_bac_8
k141_2378_1	526222.Desal_2053	4.33e-222	630.0	COG1785@1|root,COG1785@2|Bacteria,1MXI2@1224|Proteobacteria,42N40@68525|delta/epsilon subdivisions,2WKUV@28221|Deltaproteobacteria,2M83Q@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	Belongs to the alkaline phosphatase family	-	-	3.1.3.1	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	M00126	R02135,R04620	RC00017	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	-	-	-	Alk_phosphatase
k141_2378_2	926561.KB900617_gene1578	2.28e-90	281.0	COG5438@1|root,COG5438@2|Bacteria,1TPEV@1239|Firmicutes,249SW@186801|Clostridia,3WBB2@53433|Halanaerobiales	186801|Clostridia	S	PFAM YibE F family protein	-	-	-	-	-	-	-	-	-	-	-	-	YibE_F
k141_1578_1	1304885.AUEY01000012_gene1827	2.91e-178	521.0	COG0021@1|root,COG0021@2|Bacteria,1MUEY@1224|Proteobacteria,42M80@68525|delta/epsilon subdivisions,2WINJ@28221|Deltaproteobacteria,2MHY9@213118|Desulfobacterales	28221|Deltaproteobacteria	G	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate	tkt	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
k141_1578_2	245174.XP_009269367.1	1.86e-39	162.0	COG1022@1|root,KOG1180@2759|Eukaryota,39R6J@33154|Opisthokonta,3NVN8@4751|Fungi,3UZJS@5204|Basidiomycota	4751|Fungi	I	Long-chain-fatty-acid-CoA-ligase	FAA4	GO:0001676,GO:0003674,GO:0003824,GO:0004467,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005741,GO:0005783,GO:0005811,GO:0005886,GO:0006082,GO:0006139,GO:0006163,GO:0006629,GO:0006631,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006869,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0010494,GO:0010876,GO:0012505,GO:0015645,GO:0015695,GO:0015696,GO:0015711,GO:0015718,GO:0015849,GO:0015908,GO:0015909,GO:0016020,GO:0016405,GO:0016874,GO:0016877,GO:0016878,GO:0019637,GO:0019693,GO:0019752,GO:0019867,GO:0031090,GO:0031956,GO:0031957,GO:0031966,GO:0031967,GO:0031968,GO:0031975,GO:0032787,GO:0032991,GO:0033036,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035336,GO:0035337,GO:0035383,GO:0035770,GO:0036464,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0044539,GO:0046483,GO:0046942,GO:0051179,GO:0051186,GO:0051234,GO:0055086,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:0072521,GO:0090432,GO:0090433,GO:0090434,GO:0098588,GO:0098805,GO:1901135,GO:1901360,GO:1901564,GO:1901568,GO:1905329,GO:1990904	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	iMM904.YIL009W,iND750.YIL009W	AMP-binding
k141_4744_1	1031288.AXAA01000006_gene1109	1.33e-23	103.0	COG1647@1|root,COG1647@2|Bacteria,1TQ7X@1239|Firmicutes,24HZH@186801|Clostridia,36G4R@31979|Clostridiaceae	186801|Clostridia	S	Serine aminopeptidase, S33	-	-	3.1.1.1	ko:K03928	-	-	-	-	ko00000,ko01000	-	-	-	Hydrolase_4
k141_937_1	55601.VANGNB10_cII0757	1.27e-150	449.0	COG5001@1|root,COG5001@2|Bacteria,1NSEH@1224|Proteobacteria,1SJRG@1236|Gammaproteobacteria,1XUZ9@135623|Vibrionales	135623|Vibrionales	T	COG2202 FOG PAS PAC domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_3
k141_2614_1	675815.VOA_002305	7.05e-05	45.8	COG0850@1|root,COG0850@2|Bacteria,1RE6K@1224|Proteobacteria,1T0SI@1236|Gammaproteobacteria,1XTUT@135623|Vibrionales	135623|Vibrionales	D	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization	minC	-	-	ko:K03610	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	MinC_C,MinC_N
k141_2614_2	1219065.VPR01S_02_02230	9.73e-41	136.0	COG3100@1|root,COG3100@2|Bacteria,1N83J@1224|Proteobacteria,1SCCD@1236|Gammaproteobacteria,1XYIW@135623|Vibrionales	135623|Vibrionales	S	YcgL domain-containing protein	ycgL	-	-	ko:K09902	-	-	-	-	ko00000	-	-	-	YcgL
k141_2614_3	1219065.VPR01S_02_02240	4.76e-180	508.0	COG2951@1|root,COG2951@2|Bacteria,1MUZ3@1224|Proteobacteria,1RMQ6@1236|Gammaproteobacteria,1XTUP@135623|Vibrionales	135623|Vibrionales	M	Membrane-bound lytic murein transglycosylase B	mltB	-	-	ko:K08305	-	-	-	-	ko00000,ko01000,ko01011	-	GH103	-	SLT_2
k141_5017_1	1280698.AUJS01000028_gene2287	7.51e-98	289.0	COG1461@1|root,COG1461@2|Bacteria,1V4FH@1239|Firmicutes,24FUX@186801|Clostridia,27W04@189330|Dorea	186801|Clostridia	S	Dak2	-	-	2.7.1.121	ko:K05879	ko00561,ko01100,map00561,map01100	-	R01012	RC00015,RC00017	ko00000,ko00001,ko01000	-	-	-	Dak2
k141_5017_2	1280698.AUJS01000028_gene2288	9.92e-251	706.0	COG1457@1|root,COG1457@2|Bacteria,1VTCF@1239|Firmicutes	1239|Firmicutes	F	Belongs to the purine-cytosine permease (2.A.39) family	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_5017_3	1469948.JPNB01000003_gene158	2.29e-81	243.0	COG0698@1|root,COG0698@2|Bacteria,1V6HS@1239|Firmicutes,24J8M@186801|Clostridia,36JXA@31979|Clostridiaceae	186801|Clostridia	G	ribose 5-phosphate isomerase B	-	-	5.3.1.6	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01056,R09030	RC00376,RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	LacAB_rpiB
k141_2380_2	177439.DP1459	0.000497	46.2	COG4967@1|root,COG4967@2|Bacteria	2|Bacteria	NU	type IV pilus modification protein PilV	ppdC	-	-	ko:K02671,ko:K02681	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	N_methyl,T2SSppdC
k141_1580_1	1121396.KB893129_gene30	2.94e-78	244.0	COG0042@1|root,COG0042@2|Bacteria,1MV5V@1224|Proteobacteria,42M3I@68525|delta/epsilon subdivisions,2WIXZ@28221|Deltaproteobacteria,2MI4J@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	-	-	-	-	-	-	-	-	-	-	-	-	Dus
k141_4745_1	1191299.AJYX01000037_gene3303	3.29e-110	332.0	COG3434@1|root,COG3434@2|Bacteria,1MVW1@1224|Proteobacteria,1RS25@1236|Gammaproteobacteria,1XTJ5@135623|Vibrionales	135623|Vibrionales	T	signal transduction protein containing EAL and modified HD-GYP domains	-	-	3.1.4.52	ko:K07181	ko05111,map05111	-	-	-	ko00000,ko00001,ko01000	-	-	-	EAL,HDOD
k141_939_1	1123075.AUDP01000001_gene2330	3.96e-68	214.0	COG0134@1|root,COG0134@2|Bacteria,1TR94@1239|Firmicutes,249ZY@186801|Clostridia,3WG9T@541000|Ruminococcaceae	186801|Clostridia	E	Belongs to the TrpC family	trpC	-	4.1.1.48	ko:K01609	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03508	RC00944	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPS
k141_2615_1	536227.CcarbDRAFT_3755	3.41e-97	291.0	COG2014@1|root,COG2014@2|Bacteria,1V1M5@1239|Firmicutes,24CR5@186801|Clostridia,36GQK@31979|Clostridiaceae	186801|Clostridia	S	Putative heavy-metal chelation	-	-	-	-	-	-	-	-	-	-	-	-	DUF364
k141_2615_2	1187848.AJYQ01000156_gene3907	2.01e-54	172.0	2AN7V@1|root,31D5W@2|Bacteria,1RJ19@1224|Proteobacteria,1S5V8@1236|Gammaproteobacteria,1XXU3@135623|Vibrionales	135623|Vibrionales	S	Protein of unknown function (DUF2810)	yibL	-	-	ko:K14762	-	-	-	-	ko00000,ko03009	-	-	-	DUF2810
k141_4746_1	177437.HRM2_24040	5.74e-105	312.0	COG0568@1|root,COG0568@2|Bacteria,1MVWR@1224|Proteobacteria,42NRM@68525|delta/epsilon subdivisions,2WJ0S@28221|Deltaproteobacteria,2MHVP@213118|Desulfobacterales	28221|Deltaproteobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	rpoH	-	-	ko:K03086,ko:K03089	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
k141_660_1	933262.AXAM01000018_gene1009	4.53e-74	249.0	COG0501@1|root,COG3063@1|root,COG0501@2|Bacteria,COG3063@2|Bacteria,1R5A7@1224|Proteobacteria,42MP6@68525|delta/epsilon subdivisions,2WK92@28221|Deltaproteobacteria,2MIHI@213118|Desulfobacterales	28221|Deltaproteobacteria	O	PFAM peptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48,TPR_11,TPR_17
k141_660_2	350688.Clos_0655	1.2e-120	352.0	COG0428@1|root,COG0428@2|Bacteria,1TP7J@1239|Firmicutes,247Q2@186801|Clostridia,36FEF@31979|Clostridiaceae	186801|Clostridia	P	Zinc transporter	zupT	-	-	ko:K07238	-	-	-	-	ko00000,ko02000	2.A.5.5	-	-	Zip
k141_660_3	56107.Cylst_1851	9.75e-35	124.0	COG1186@1|root,COG1186@2|Bacteria,1G5Y2@1117|Cyanobacteria,1HNFX@1161|Nostocales	1117|Cyanobacteria	J	Protein chain release factor B	-	-	-	ko:K15034	-	-	-	-	ko00000,ko03012	-	-	-	RF-1
k141_660_4	1121324.CLIT_11c01710	4.83e-49	175.0	COG1502@1|root,COG1502@2|Bacteria,1TQ2Q@1239|Firmicutes,24D0N@186801|Clostridia	186801|Clostridia	I	PLD-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PLDc_2
k141_2931_3	696281.Desru_3127	4.63e-24	102.0	COG2963@1|root,COG2963@2|Bacteria,1V4FD@1239|Firmicutes,24GUY@186801|Clostridia,264CX@186807|Peptococcaceae	186801|Clostridia	L	Winged helix-turn helix	-	-	-	-	-	-	-	-	-	-	-	-	HTH_28,HTH_Tnp_1
k141_2931_4	632245.CLP_0453	8.94e-30	108.0	COG1343@1|root,COG1343@2|Bacteria,1VAV3@1239|Firmicutes,24NM2@186801|Clostridia,36KIF@31979|Clostridiaceae	186801|Clostridia	L	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette	cas2	-	-	ko:K09951	-	-	-	-	ko00000,ko02048	-	-	-	CRISPR_Cas2
k141_2931_5	386415.NT01CX_0201	1.58e-52	171.0	COG1468@1|root,COG1468@2|Bacteria,1V3RV@1239|Firmicutes,25D41@186801|Clostridia,36U6R@31979|Clostridiaceae	186801|Clostridia	L	CRISPR-associated protein Cas4	cas4	-	3.1.12.1	ko:K07464	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	Cas_Cas4
k141_2931_6	990073.ATHU01000001_gene412	6.77e-121	358.0	COG1518@1|root,COG1518@2|Bacteria,1MUKK@1224|Proteobacteria,42NHJ@68525|delta/epsilon subdivisions,2YNDV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette	cas1	-	-	ko:K15342	-	-	-	-	ko00000,ko02048,ko03400	-	-	-	Cas_Cas1
k141_4747_1	1348635.BBJY01000003_gene3848	2.43e-32	115.0	2BHGR@1|root,32BIW@2|Bacteria,1QKP8@1224|Proteobacteria,1TITJ@1236|Gammaproteobacteria,1XZMQ@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_4747_2	243277.VC_A0925	2.35e-94	285.0	COG0418@1|root,COG0418@2|Bacteria,1MUYP@1224|Proteobacteria,1RNEN@1236|Gammaproteobacteria,1XSNV@135623|Vibrionales	135623|Vibrionales	F	Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate	pyrC	GO:0003674,GO:0003824,GO:0004151,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
k141_661_1	1121451.DESAM_21130	4.17e-59	191.0	COG0631@1|root,COG0631@2|Bacteria,1R84Y@1224|Proteobacteria,42MVE@68525|delta/epsilon subdivisions,2WK9T@28221|Deltaproteobacteria,2MAS9@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	Protein phosphatase 2C	-	-	-	-	-	-	-	-	-	-	-	-	PP2C_2
k141_4748_1	439235.Dalk_4992	6.11e-36	130.0	COG4820@1|root,COG4820@2|Bacteria,1MVXX@1224|Proteobacteria,42RX2@68525|delta/epsilon subdivisions,2WNFA@28221|Deltaproteobacteria,2MMXD@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Type IV pilus assembly protein PilM;	-	-	-	ko:K04024	-	-	-	-	ko00000	-	-	-	MreB_Mbl,PilM_2
k141_4748_2	439235.Dalk_4991	1.51e-79	245.0	COG0452@1|root,COG0452@2|Bacteria	2|Bacteria	H	phosphopantothenoylcysteine decarboxylase activity	-	-	-	-	-	-	-	-	-	-	-	-	Flavoprotein
k141_2934_1	1121396.KB893058_gene2557	6.68e-71	219.0	COG0655@1|root,COG0655@2|Bacteria,1RAZP@1224|Proteobacteria,42QXN@68525|delta/epsilon subdivisions,2WMR3@28221|Deltaproteobacteria,2MJJH@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Flavodoxin-like fold	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
k141_2618_3	1304885.AUEY01000001_gene3306	2.63e-55	177.0	COG1406@1|root,COG1406@2|Bacteria,1RATZ@1224|Proteobacteria,42R2Q@68525|delta/epsilon subdivisions,2WP6F@28221|Deltaproteobacteria,2MJQ2@213118|Desulfobacterales	28221|Deltaproteobacteria	N	Chemotaxis phosphatase CheX	-	-	-	ko:K03409	ko02030,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheX
k141_2618_4	41875.XP_007511301.1	5.97e-93	285.0	COG0031@1|root,KOG1252@2759|Eukaryota,37MTM@33090|Viridiplantae,34H3B@3041|Chlorophyta	3041|Chlorophyta	E	Belongs to the cysteine synthase cystathionine beta- synthase family	-	-	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
k141_2935_1	945543.VIBR0546_21670	2.58e-41	152.0	COG0556@1|root,COG0556@2|Bacteria,1MUFK@1224|Proteobacteria,1RN6Z@1236|Gammaproteobacteria,1XV2Z@135623|Vibrionales	135623|Vibrionales	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
k141_2935_2	675815.VOA_000612	6.14e-89	275.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria,1XTGI@135623|Vibrionales	135623|Vibrionales	T	COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains	luxO	GO:0000156,GO:0000160,GO:0003674,GO:0003700,GO:0006355,GO:0007154,GO:0007165,GO:0008150,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0023052,GO:0031323,GO:0031326,GO:0035556,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0051716,GO:0060089,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2001141	-	ko:K10912	ko02020,ko02024,ko05111,map02020,map02024,map05111	M00513	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
k141_5018_1	1128912.GMES_4308	7.57e-255	707.0	COG1875@1|root,COG1875@2|Bacteria,1MUX1@1224|Proteobacteria,1RMQN@1236|Gammaproteobacteria,4653M@72275|Alteromonadaceae	1236|Gammaproteobacteria	T	ATPase related to phosphate starvation-inducible protein PhoH	phoH	-	-	ko:K07175	-	-	-	-	ko00000	-	-	-	PIN_4,PhoH
k141_5018_2	314292.VAS14_11054	9.41e-67	218.0	COG0477@1|root,COG2814@2|Bacteria,1MVVW@1224|Proteobacteria,1RMXR@1236|Gammaproteobacteria,1XY77@135623|Vibrionales	135623|Vibrionales	EGP	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
k141_5018_3	1225785.CM001983_gene1290	1.26e-58	189.0	COG0637@1|root,COG0637@2|Bacteria	2|Bacteria	S	phosphonoacetaldehyde hydrolase activity	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2,Hydrolase
k141_5018_4	866895.HBHAL_2296	2.52e-98	306.0	COG0304@1|root,COG0304@2|Bacteria,1TPA7@1239|Firmicutes,4H9SD@91061|Bacilli,3NDCQ@45667|Halobacillus	91061|Bacilli	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabF	-	2.3.1.179	ko:K09458,ko:K14660	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	iSB619.SA_RS04785	Ketoacyl-synt_C,ketoacyl-synt
k141_2619_2	765913.ThidrDRAFT_4523	4.78e-28	119.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,1X0E7@135613|Chromatiales	135613|Chromatiales	NT	Chemoreceptor zinc-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	CZB,MCPsignal
k141_2029_2	96561.Dole_2319	2.05e-26	101.0	COG1359@1|root,COG1359@2|Bacteria,1NGPW@1224|Proteobacteria,42TXG@68525|delta/epsilon subdivisions,2WQI4@28221|Deltaproteobacteria,2MKN6@213118|Desulfobacterales	28221|Deltaproteobacteria	S	PFAM Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	ABM
k141_2029_3	1232437.KL662040_gene2136	5.17e-237	665.0	COG1032@1|root,COG1032@2|Bacteria,1MY2Y@1224|Proteobacteria,42NG3@68525|delta/epsilon subdivisions,2WJ95@28221|Deltaproteobacteria,2MJ57@213118|Desulfobacterales	28221|Deltaproteobacteria	C	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,DUF4070,Radical_SAM
k141_1711_2	439235.Dalk_4829	4.2e-57	186.0	COG0671@1|root,COG0671@2|Bacteria,1NIKP@1224|Proteobacteria,42XWV@68525|delta/epsilon subdivisions,2WT1Z@28221|Deltaproteobacteria,2MNS3@213118|Desulfobacterales	28221|Deltaproteobacteria	I	PAP2 superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PAP2_3
k141_18_1	555779.Dthio_PD3123	6.38e-37	127.0	COG3370@1|root,COG3370@2|Bacteria,1N3DX@1224|Proteobacteria,42UA2@68525|delta/epsilon subdivisions,2WQ2I@28221|Deltaproteobacteria,2MCZA@213115|Desulfovibrionales	28221|Deltaproteobacteria	O	peroxiredoxin activity	-	-	-	-	-	-	-	-	-	-	-	-	DrsE
k141_18_2	933262.AXAM01000083_gene762	1.11e-187	532.0	COG0426@1|root,COG0426@2|Bacteria,1R4UD@1224|Proteobacteria,43AF5@68525|delta/epsilon subdivisions,2X5UW@28221|Deltaproteobacteria,2MPG5@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Flavodoxin	roo	-	-	-	-	-	-	-	-	-	-	-	Flavodoxin_1,Lactamase_B,Lactamase_B_2
k141_18_3	997884.HMPREF1068_04200	4e-27	99.0	COG1773@1|root,COG1773@2|Bacteria,4NHF0@976|Bacteroidetes,2FUN6@200643|Bacteroidia,4AS7V@815|Bacteroidaceae	976|Bacteroidetes	C	Psort location Cytoplasmic, score	rubR	-	-	-	-	-	-	-	-	-	-	-	Rubredoxin
k141_18_4	517417.Cpar_1902	4.14e-23	89.0	COG1773@1|root,COG1773@2|Bacteria,1FEAJ@1090|Chlorobi	1090|Chlorobi	C	Rubredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Rubredoxin
k141_1712_1	1167006.UWK_01809	1.66e-14	81.3	COG0457@1|root,COG3307@1|root,COG0457@2|Bacteria,COG3307@2|Bacteria,1N225@1224|Proteobacteria,42QDQ@68525|delta/epsilon subdivisions,2WM6B@28221|Deltaproteobacteria,2MIM4@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Lipid A core-O-antigen ligase-like enyme	-	-	-	ko:K18814	-	-	-	-	ko00000,ko02000	9.B.67.1	-	-	TPR_14,TPR_16,TPR_8,Wzy_C
k141_3075_2	1304885.AUEY01000089_gene130	1.51e-195	561.0	COG2067@1|root,COG2067@2|Bacteria,1MUU4@1224|Proteobacteria,42N9J@68525|delta/epsilon subdivisions,2WKR7@28221|Deltaproteobacteria,2MITN@213118|Desulfobacterales	28221|Deltaproteobacteria	I	PFAM membrane protein involved in aromatic hydrocarbon degradation	-	-	-	ko:K06076	-	-	-	-	ko00000,ko02000	1.B.9	-	-	Toluene_X
k141_1713_2	177437.HRM2_30670	1.38e-43	155.0	2DBU2@1|root,2ZB3S@2|Bacteria,1N1MT@1224|Proteobacteria,42VJX@68525|delta/epsilon subdivisions,2WSPP@28221|Deltaproteobacteria,2MNKM@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_4
k141_3076_1	1121405.dsmv_3410	1.58e-25	108.0	COG0770@1|root,COG0770@2|Bacteria,1QTSF@1224|Proteobacteria,42MXF@68525|delta/epsilon subdivisions,2WIJZ@28221|Deltaproteobacteria,2MIES@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
k141_3077_1	926550.CLDAP_07620	7.14e-26	114.0	COG0236@1|root,COG0304@1|root,COG1028@1|root,COG3321@1|root,COG0236@2|Bacteria,COG0304@2|Bacteria,COG1028@2|Bacteria,COG3321@2|Bacteria,2G68I@200795|Chloroflexi	200795|Chloroflexi	IQ	PFAM short-chain dehydrogenase reductase SDR	-	-	-	ko:K15314	ko01059,ko01130,map01059,map01130	M00824,M00825	R11435	-	ko00000,ko00001,ko00002,ko01008	-	-	-	Acyl_transf_1,KAsynt_C_assoc,KR,Ketoacyl-synt_C,PP-binding,PS-DH,ketoacyl-synt
k141_3753_1	1304885.AUEY01000020_gene3513	1.2e-70	218.0	COG0664@1|root,COG0664@2|Bacteria,1QHKB@1224|Proteobacteria,42RR8@68525|delta/epsilon subdivisions,2WN8W@28221|Deltaproteobacteria,2MJUH@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
k141_3753_2	1232437.KL662016_gene1132	9.59e-157	449.0	COG0535@1|root,COG0535@2|Bacteria,1R4SH@1224|Proteobacteria,42NZR@68525|delta/epsilon subdivisions,2WKQA@28221|Deltaproteobacteria,2MHSP@213118|Desulfobacterales	28221|Deltaproteobacteria	S	PFAM Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM
k141_3753_3	177437.HRM2_06970	1.78e-169	487.0	COG2871@1|root,COG2871@2|Bacteria,1QTUV@1224|Proteobacteria,42MXC@68525|delta/epsilon subdivisions,2WJJF@28221|Deltaproteobacteria,2MIP9@213118|Desulfobacterales	28221|Deltaproteobacteria	C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway	nqrF	-	1.6.5.8	ko:K00351	-	-	-	-	ko00000,ko01000	-	-	-	FAD_binding_6,Fer2,NAD_binding_1
k141_3753_4	96561.Dole_2540	1.24e-102	301.0	COG2209@1|root,COG2209@2|Bacteria,1R33S@1224|Proteobacteria,42N3Q@68525|delta/epsilon subdivisions,2WJSA@28221|Deltaproteobacteria,2MIWQ@213118|Desulfobacterales	28221|Deltaproteobacteria	C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol	nqrE	-	1.6.5.8	ko:K00350	-	-	-	-	ko00000,ko01000	-	-	-	Rnf-Nqr
k141_3753_5	96561.Dole_2539	6.22e-86	259.0	COG1347@1|root,COG1347@2|Bacteria,1MUZR@1224|Proteobacteria,42QT5@68525|delta/epsilon subdivisions,2WN1N@28221|Deltaproteobacteria,2MHSZ@213118|Desulfobacterales	28221|Deltaproteobacteria	C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol	nqrD	-	1.6.5.8	ko:K00349	-	-	-	-	ko00000,ko01000	-	-	-	Rnf-Nqr
k141_3753_6	96561.Dole_2538	1.48e-68	218.0	COG2869@1|root,COG2869@2|Bacteria,1MVDI@1224|Proteobacteria,42RMS@68525|delta/epsilon subdivisions,2WNG3@28221|Deltaproteobacteria,2MIBV@213118|Desulfobacterales	28221|Deltaproteobacteria	C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol	nqrC	-	1.6.5.8	ko:K00348	-	-	-	-	ko00000,ko01000	-	-	-	FMN_bind
k141_3753_7	96561.Dole_2537	8.25e-162	466.0	COG1805@1|root,COG1805@2|Bacteria,1QTUU@1224|Proteobacteria,43BRU@68525|delta/epsilon subdivisions,2X72N@28221|Deltaproteobacteria,2MIN5@213118|Desulfobacterales	28221|Deltaproteobacteria	C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol	nqrB	-	1.6.5.8	ko:K00347	-	-	-	-	ko00000,ko01000	-	-	-	NQR2_RnfD_RnfE
k141_3753_8	283942.IL1050	2.82e-26	115.0	COG1726@1|root,COG1726@2|Bacteria,1MU36@1224|Proteobacteria,1RPU1@1236|Gammaproteobacteria,2QFKP@267893|Idiomarinaceae	1236|Gammaproteobacteria	C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol	nqrA	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008137,GO:0008150,GO:0008152,GO:0015672,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030001,GO:0030964,GO:0032991,GO:0044425,GO:0050136,GO:0051179,GO:0051234,GO:0055114,GO:0098796,GO:1902494	1.6.5.8	ko:K00346	-	-	-	-	ko00000,ko01000	-	-	-	NQRA,NQRA_SLBB
k141_1714_1	1007103.AFHW01000032_gene2242	2.2e-28	119.0	COG1775@1|root,COG1775@2|Bacteria,1TPEF@1239|Firmicutes,4HW8T@91061|Bacilli,26W7T@186822|Paenibacillaceae	91061|Bacilli	E	2-hydroxyglutaryl-CoA dehydratase, D-component	-	-	-	-	-	-	-	-	-	-	-	-	HGD-D
k141_346_1	1408823.AXUS01000040_gene1666	2.31e-42	140.0	2DPII@1|root,3327T@2|Bacteria,1VHT9@1239|Firmicutes,24RHP@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_346_2	1163671.JAGI01000002_gene2940	2.4e-05	43.9	2BEYZ@1|root,328QN@2|Bacteria,1UUNU@1239|Firmicutes,2579Y@186801|Clostridia,36TX1@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_346_3	1205681.CALW02000073_gene1919	1.05e-15	68.9	2AIDV@1|root,318V9@2|Bacteria,1Q10S@1224|Proteobacteria,2V5CE@28211|Alphaproteobacteria,48UFJ@772|Bartonellaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_3079_1	573413.Spirs_3134	6.09e-97	301.0	COG1022@1|root,COG1022@2|Bacteria,2J9W8@203691|Spirochaetes	203691|Spirochaetes	I	PFAM AMP-dependent synthetase	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
k141_20_1	1442598.JABW01000017_gene1953	1.4e-38	157.0	COG2931@1|root,COG3210@1|root,COG3468@1|root,COG4254@1|root,COG4932@1|root,COG5295@1|root,COG2931@2|Bacteria,COG3210@2|Bacteria,COG3468@2|Bacteria,COG4254@2|Bacteria,COG4932@2|Bacteria,COG5295@2|Bacteria,1MU7T@1224|Proteobacteria,43CIF@68525|delta/epsilon subdivisions,2YR7K@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	QU	Domain of unknown function (DUF4347)	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin,DUF4347,He_PIG
k141_1715_2	485916.Dtox_2561	4.28e-59	184.0	COG5561@1|root,COG5561@2|Bacteria,1V8K2@1239|Firmicutes,24HKJ@186801|Clostridia,26572@186807|Peptococcaceae	186801|Clostridia	S	CGGC	-	-	-	-	-	-	-	-	-	-	-	-	CGGC
k141_1038_1	237368.SCABRO_02513	1.69e-74	235.0	COG1883@1|root,COG1883@2|Bacteria,2IYPW@203682|Planctomycetes	203682|Planctomycetes	C	Na+-transporting oxaloacetate decarboxylase beta subunit	-	-	4.1.1.3	ko:K01572	ko00620,ko01100,map00620,map01100	-	R00217	RC00040	ko00000,ko00001,ko01000,ko02000	3.B.1.1.1	-	-	OAD_beta
k141_1038_2	1304885.AUEY01000085_gene2475	3.36e-107	317.0	COG1024@1|root,COG1024@2|Bacteria,1N2V7@1224|Proteobacteria,42UXR@68525|delta/epsilon subdivisions,2WQCT@28221|Deltaproteobacteria,2MI0D@213118|Desulfobacterales	28221|Deltaproteobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
k141_1038_3	1304885.AUEY01000025_gene2763	6.02e-50	163.0	COG1846@1|root,COG1846@2|Bacteria,1RH1F@1224|Proteobacteria,42VBV@68525|delta/epsilon subdivisions,2WRQ4@28221|Deltaproteobacteria,2MM2K@213118|Desulfobacterales	28221|Deltaproteobacteria	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR
k141_1038_4	1304885.AUEY01000005_gene800	0.0	892.0	COG1960@1|root,COG1960@2|Bacteria,1R15B@1224|Proteobacteria,42MUT@68525|delta/epsilon subdivisions,2WJ8T@28221|Deltaproteobacteria,2MI3E@213118|Desulfobacterales	28221|Deltaproteobacteria	C	acyl-CoA dehydrogenase	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1
k141_347_1	706587.Desti_2481	4.88e-138	420.0	COG0178@1|root,COG0178@2|Bacteria,1MW0W@1224|Proteobacteria,42M4I@68525|delta/epsilon subdivisions,2WJHM@28221|Deltaproteobacteria,2MQYN@213462|Syntrophobacterales	28221|Deltaproteobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
k141_347_2	1121405.dsmv_0364	5.08e-29	105.0	COG0636@1|root,COG0636@2|Bacteria,1NAIE@1224|Proteobacteria,42VAI@68525|delta/epsilon subdivisions,2WRI4@28221|Deltaproteobacteria,2MKRV@213118|Desulfobacterales	28221|Deltaproteobacteria	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpE	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
k141_3081_1	198628.Dda3937_01325	2.93e-91	282.0	COG0477@1|root,COG2814@2|Bacteria,1QUAS@1224|Proteobacteria,1RPFC@1236|Gammaproteobacteria,2JD2X@204037|Dickeya	1236|Gammaproteobacteria	EGP	PFAM major facilitator superfamily MFS_1	yebQ	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944	-	ko:K08169	-	-	-	-	ko00000,ko02000	2.A.1.3.17	-	-	MFS_1
k141_21_1	1096546.WYO_1028	1.44e-18	96.7	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2TQS3@28211|Alphaproteobacteria,1JTFZ@119045|Methylobacteriaceae	28211|Alphaproteobacteria	T	PFAM GGDEF domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	4HB_MCP_1,EAL,GGDEF,HAMP,MHYT,PAS,PAS_3,PAS_7,PAS_8,dCache_1
k141_21_2	1523503.JPMY01000045_gene123	4.31e-40	150.0	COG2366@1|root,COG2366@2|Bacteria,1MVMH@1224|Proteobacteria,1RPRP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	COG2366 Protein related to penicillin acylase	quiP	-	3.5.1.11,3.5.1.97	ko:K01434,ko:K07116	ko00311,ko01130,map00311,map01130	-	R02170	RC00166,RC00328	ko00000,ko00001,ko01000,ko01002	-	-	-	Penicil_amidase
k141_692_2	675813.VIB_000161	1.99e-57	179.0	COG2026@1|root,COG2026@2|Bacteria,1PW09@1224|Proteobacteria,1TC7R@1236|Gammaproteobacteria,1Y151@135623|Vibrionales	135623|Vibrionales	DJ	ParE-like toxin of type II bacterial toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	ParE_toxin
k141_692_3	675813.VIB_000162	8.33e-37	125.0	COG2161@1|root,COG2161@2|Bacteria	2|Bacteria	D	toxin-antitoxin pair type II binding	-	-	-	ko:K18923	-	-	-	-	ko00000,ko02048	-	-	-	PhdYeFM_antitox
k141_692_4	675817.VDA_001527	1.14e-61	201.0	COG3328@1|root,COG3328@2|Bacteria,1MU4P@1224|Proteobacteria,1RNB3@1236|Gammaproteobacteria,1XVNR@135623|Vibrionales	135623|Vibrionales	L	Transposase, Mutator family	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_mut
k141_692_5	203119.Cthe_2862	2.96e-13	72.0	2CG6A@1|root,2ZVAK@2|Bacteria,1W2RE@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_692_6	641149.HMPREF9016_01912	2.56e-18	97.4	COG3210@1|root,COG3210@2|Bacteria,1N97Y@1224|Proteobacteria,2W451@28216|Betaproteobacteria	28216|Betaproteobacteria	U	Neisseria toxin MafB	-	-	-	-	-	-	-	-	-	-	-	-	MafB,PT-HINT
k141_1717_2	675813.VIB_000196	4.88e-64	196.0	COG3436@1|root,COG3436@2|Bacteria,1N638@1224|Proteobacteria,1SFHC@1236|Gammaproteobacteria,1Y280@135623|Vibrionales	1236|Gammaproteobacteria	L	IS66 Orf2 like protein	-	-	-	-	-	-	-	-	-	-	-	-	TnpB_IS66
k141_1717_3	1535422.ND16A_0183	5.42e-207	592.0	COG3316@1|root,COG3316@2|Bacteria	1535422.ND16A_0183|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_1039_1	1265505.ATUG01000001_gene3311	0.0	1090.0	COG0189@1|root,COG0769@1|root,COG0189@2|Bacteria,COG0769@2|Bacteria,1MVN2@1224|Proteobacteria,42PUY@68525|delta/epsilon subdivisions,2WM1C@28221|Deltaproteobacteria	28221|Deltaproteobacteria	HJ	RimK-like ATP-grasp domain	-	-	6.3.2.29,6.3.2.30	ko:K03802	-	-	-	-	ko00000,ko01000	-	-	-	Mur_ligase_C,Mur_ligase_M,RimK
k141_22_2	1125863.JAFN01000001_gene218	6.74e-08	55.5	COG1334@1|root,COG1334@2|Bacteria	2|Bacteria	N	flagellar protein FlaG	flaG	-	-	ko:K06603	-	-	-	-	ko00000,ko02035	-	-	-	FlaG
k141_22_3	1243664.CAVL020000039_gene560	2.25e-14	68.6	COG1551@1|root,COG1551@2|Bacteria,1VEEF@1239|Firmicutes,4HNPJ@91061|Bacilli,1ZJ2S@1386|Bacillus	91061|Bacilli	T	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding	csrA	-	-	ko:K03563	ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03019	-	-	-	CsrA
k141_22_4	635013.TherJR_2795	4.1e-35	126.0	COG1699@1|root,COG1699@2|Bacteria,1VA6Y@1239|Firmicutes,24QXE@186801|Clostridia,262RK@186807|Peptococcaceae	186801|Clostridia	S	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum	fliW	-	-	ko:K13626	-	-	-	-	ko00000,ko02035	-	-	-	FliW
k141_22_5	933262.AXAM01000077_gene1703	3.02e-17	80.9	COG0569@1|root,COG0569@2|Bacteria,1MW8R@1224|Proteobacteria,42NWZ@68525|delta/epsilon subdivisions,2WJU7@28221|Deltaproteobacteria,2MJ2C@213118|Desulfobacterales	28221|Deltaproteobacteria	P	PFAM TrkA-N domain	trkA	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
k141_1040_1	595494.Tola_1945	1.85e-68	218.0	COG2207@1|root,COG3837@1|root,COG2207@2|Bacteria,COG3837@2|Bacteria,1MXT6@1224|Proteobacteria,1RXTQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	transcriptional regulator	yisR	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
k141_694_1	497321.C664_03075	1.62e-34	123.0	COG0818@1|root,COG0818@2|Bacteria,1MZ3Q@1224|Proteobacteria,2VU5Y@28216|Betaproteobacteria,2KWKX@206389|Rhodocyclales	206389|Rhodocyclales	M	Recycling of diacylglycerol produced during the turnover of membrane phospholipid	-	-	2.7.1.107	ko:K00901	ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00561,map00564,map01100,map01110,map04070,map04072,map05231	-	R02240	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	DAGK_prokar
k141_3754_1	93060.P9215_02491	1.55e-06	51.2	COG2046@1|root,COG2046@2|Bacteria,1G0E8@1117|Cyanobacteria,1MM01@1212|Prochloraceae	1117|Cyanobacteria	P	Alternative locus ID	sat	-	2.7.7.4	ko:K00958	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R04929	RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-sulfurylase,PUA_2
k141_3754_2	1347393.HG726026_gene2436	8.46e-82	254.0	COG1218@1|root,COG1218@2|Bacteria,4NFHY@976|Bacteroidetes,2FP00@200643|Bacteroidia,4AMGH@815|Bacteroidaceae	976|Bacteroidetes	P	3'(2'),5'-bisphosphate nucleotidase	cysQ	-	3.1.3.7	ko:K01082	ko00920,ko01100,ko01120,ko01130,map00920,map01100,map01120,map01130	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03016	-	-	-	Inositol_P
k141_3754_3	1248760.ANFZ01000011_gene227	4.92e-05	48.5	COG0489@1|root,COG0489@2|Bacteria,1MU7R@1224|Proteobacteria,2TRDM@28211|Alphaproteobacteria,2K1RH@204457|Sphingomonadales	204457|Sphingomonadales	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	-	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	ParA
k141_3754_5	1304885.AUEY01000097_gene2882	6.99e-265	753.0	COG3243@1|root,COG3243@2|Bacteria,1MUNE@1224|Proteobacteria,42PDZ@68525|delta/epsilon subdivisions,2WIW0@28221|Deltaproteobacteria,2MJ1X@213118|Desulfobacterales	28221|Deltaproteobacteria	I	Protein of unknown function (DUF3141)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3141,TerB
k141_1718_1	1499684.CCNP01000018_gene1035	0.000655	44.7	COG0745@1|root,COG0745@2|Bacteria,1TR32@1239|Firmicutes,249TG@186801|Clostridia,36EMS@31979|Clostridiaceae	186801|Clostridia	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
k141_1041_1	518637.EUBIFOR_01660	4.2e-23	99.0	COG0663@1|root,COG1247@1|root,COG0663@2|Bacteria,COG1247@2|Bacteria,1V6CZ@1239|Firmicutes,3VR41@526524|Erysipelotrichia	526524|Erysipelotrichia	M	Bacterial transferase hexapeptide (six repeats)	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_4,Hexapep
k141_3082_1	1187848.AJYQ01000061_gene54	5.97e-38	132.0	COG3637@1|root,COG3637@2|Bacteria,1RHVI@1224|Proteobacteria,1S6UY@1236|Gammaproteobacteria,1XVZ1@135623|Vibrionales	135623|Vibrionales	M	OmpA-like transmembrane domain	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl
k141_3082_2	561229.Dd1591_2702	6.55e-114	340.0	COG0673@1|root,COG0673@2|Bacteria,1MZIG@1224|Proteobacteria,1RS5T@1236|Gammaproteobacteria,2JETW@204037|Dickeya	1236|Gammaproteobacteria	C	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
k141_3082_4	701176.VIBRN418_02177	5.88e-13	63.5	2AX0D@1|root,31NYE@2|Bacteria,1QKMS@1224|Proteobacteria,1TIS9@1236|Gammaproteobacteria,1XZJI@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_3082_5	319236.JCM19294_2076	5.24e-73	228.0	COG0778@1|root,COG0778@2|Bacteria,4NEW3@976|Bacteroidetes,1I0AF@117743|Flavobacteriia,3HKW2@363408|Nonlabens	976|Bacteroidetes	C	Nitroreductase family	-	-	1.5.1.34	ko:K10679	ko00633,ko01120,map00633,map01120	-	R08014,R08017,R08042	RC00250	ko00000,ko00001,ko01000	-	-	-	Nitroreductase
k141_695_1	83406.HDN1F_00880	1.46e-65	228.0	COG5002@1|root,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,1T1JE@1236|Gammaproteobacteria,1JC0K@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	T	Histidine Phosphotransfer domain	-	-	2.7.13.3	ko:K10715,ko:K20974	ko02020,ko02024,ko02025,map02020,map02024,map02025	M00517,M00820	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF3365,HAMP,HATPase_c,HisKA,Hpt,PAS,PAS_4,PAS_9,Response_reg
k141_1366_1	913865.DOT_6066	2.43e-23	98.2	COG3464@1|root,COG4584@1|root,COG3464@2|Bacteria,COG4584@2|Bacteria,1VE6P@1239|Firmicutes,24EJ6@186801|Clostridia	186801|Clostridia	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISL3
k141_1366_2	904293.HMPREF9176_1051	2.06e-13	71.6	COG0338@1|root,COG0338@2|Bacteria	2|Bacteria	L	D12 class N6 adenine-specific DNA methyltransferase	dam	-	2.1.1.72	ko:K06223	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko02048,ko03032,ko03400	-	-	-	MethyltransfD12
k141_1366_3	585394.RHOM_02055	5.88e-147	420.0	COG0863@1|root,COG0863@2|Bacteria,1V0ZF@1239|Firmicutes,24CQV@186801|Clostridia	186801|Clostridia	L	Belongs to the N(4) N(6)-methyltransferase family	-	-	2.1.1.72	ko:K00571	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	N6_N4_Mtase
k141_1366_4	1410613.JNKF01000010_gene353	4.88e-219	652.0	COG0286@1|root,COG0286@2|Bacteria	2|Bacteria	V	site-specific DNA-methyltransferase (adenine-specific) activity	-	-	2.1.1.72	ko:K03427	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	N6_Mtase
k141_1366_6	1121342.AUCO01000015_gene2681	1.18e-55	194.0	COG3012@1|root,COG3012@2|Bacteria,1U6IR@1239|Firmicutes,24QIU@186801|Clostridia,36EQZ@31979|Clostridiaceae	186801|Clostridia	S	SEC-C motif	-	-	-	-	-	-	-	-	-	-	-	-	SEC-C
k141_1366_8	509191.AEDB02000016_gene69	3.1e-28	113.0	COG1106@1|root,COG1106@2|Bacteria,1TPJN@1239|Firmicutes,249WF@186801|Clostridia,3WIMF@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AAA_15,AAA_21,AAA_23
k141_1366_9	1195236.CTER_1484	1.95e-218	613.0	COG2865@1|root,COG2865@2|Bacteria,1TSPK@1239|Firmicutes,249QT@186801|Clostridia,3WK2A@541000|Ruminococcaceae	186801|Clostridia	K	Putative ATP-dependent DNA helicase recG C-terminal	-	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AlbA_2,HATPase_c_4
k141_1366_10	1218173.BALCAV_0218245	6.57e-25	94.4	COG4895@1|root,COG4895@2|Bacteria,1VEG3@1239|Firmicutes,4HNJA@91061|Bacilli,1ZIX5@1386|Bacillus	91061|Bacilli	S	Uncharacterized conserved protein (DUF2196)	ywbE	-	-	-	-	-	-	-	-	-	-	-	DUF2196
k141_1366_11	1382305.AZUC01000016_gene2661	1.05e-13	67.8	COG0457@1|root,COG0457@2|Bacteria,1V3U6@1239|Firmicutes,4HFWW@91061|Bacilli,26FJY@186818|Planococcaceae	91061|Bacilli	S	Tetratrico peptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_5,TPR_6,TPR_8
k141_4436_37	1035196.HMPREF9998_00380	1.83e-139	400.0	COG0395@1|root,COG0395@2|Bacteria,1TR45@1239|Firmicutes,24A48@186801|Clostridia,25S66@186804|Peptostreptococcaceae	186801|Clostridia	P	ABC transporter permease	-	-	-	ko:K10119	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	BPD_transp_1
k141_4436_38	1219626.HMPREF1639_08295	4.95e-154	439.0	COG1175@1|root,COG1175@2|Bacteria,1TP1Q@1239|Firmicutes,24ADV@186801|Clostridia,25R8S@186804|Peptostreptococcaceae	186801|Clostridia	P	ABC transporter permease	-	-	-	ko:K10118	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	BPD_transp_1
k141_4436_39	634956.Geoth_3123	7.49e-211	594.0	COG1653@1|root,COG1653@2|Bacteria,1TQHT@1239|Firmicutes,4HAH2@91061|Bacilli	91061|Bacilli	G	ABC transporter, substratebinding protein	-	-	-	ko:K10117	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	SBP_bac_8
k141_4436_40	1031288.AXAA01000039_gene85	2.14e-90	281.0	COG1609@1|root,COG1609@2|Bacteria,1TPZM@1239|Firmicutes,248WQ@186801|Clostridia,36GJ7@31979|Clostridiaceae	186801|Clostridia	K	lacI family	-	-	5.1.1.1	ko:K01775,ko:K02529	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011,ko03000	-	-	-	LacI,Peripla_BP_3
k141_4436_41	1443125.Z962_04580	8.67e-163	474.0	COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,247YX@186801|Clostridia,36DT9@31979|Clostridiaceae	186801|Clostridia	V	Mate efflux family protein	mepA_10	-	-	-	-	-	-	-	-	-	-	-	MatE
k141_4436_42	562983.HMPREF0433_00984	1.63e-16	73.9	COG0694@1|root,COG0694@2|Bacteria,1VAAU@1239|Firmicutes,4HKQ8@91061|Bacilli,3WF1F@539002|Bacillales incertae sedis	91061|Bacilli	O	NifU-like domain	yutI	-	-	-	-	-	-	-	-	-	-	-	NifU
k141_4436_43	272563.CD630_34120	0.0	935.0	COG0556@1|root,COG0556@2|Bacteria,1TPKB@1239|Firmicutes,247P7@186801|Clostridia,25QUX@186804|Peptostreptococcaceae	186801|Clostridia	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
k141_4436_44	1121324.CLIT_13c01680	0.0	1406.0	COG0178@1|root,COG0178@2|Bacteria,1TPIJ@1239|Firmicutes,2485F@186801|Clostridia,25QCP@186804|Peptostreptococcaceae	186801|Clostridia	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
k141_4436_46	272563.CD630_34100	4.29e-202	585.0	COG0322@1|root,COG0322@2|Bacteria,1TP4B@1239|Firmicutes,247TQ@186801|Clostridia,25R2J@186804|Peptostreptococcaceae	186801|Clostridia	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	-	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N
k141_4436_47	272563.CD630_34090	2.49e-136	395.0	COG1493@1|root,COG1493@2|Bacteria,1TP5Z@1239|Firmicutes,24999@186801|Clostridia,25QP9@186804|Peptostreptococcaceae	186801|Clostridia	F	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion	hprK	-	-	ko:K06023	-	-	-	-	ko00000,ko01000	-	-	-	Hpr_kinase_C,Hpr_kinase_N
k141_4436_48	1304284.L21TH_2538	4.15e-58	185.0	COG1905@1|root,COG1905@2|Bacteria,1V737@1239|Firmicutes,24HFB@186801|Clostridia,36IZJ@31979|Clostridiaceae	186801|Clostridia	C	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit	nuoE	-	1.12.1.3,1.17.1.11,1.6.5.3	ko:K00334,ko:K18330,ko:K22340	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx
k141_4436_49	428125.CLOLEP_03892	2.46e-177	520.0	COG1894@1|root,COG1894@2|Bacteria,1TQB0@1239|Firmicutes,2483E@186801|Clostridia,3WGG2@541000|Ruminococcaceae	186801|Clostridia	C	NADH ubiquinone oxidoreductase	hymB	-	1.12.1.3,1.17.1.11,1.6.5.3	ko:K00335,ko:K18331,ko:K22339	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx,Complex1_51K,Fer4,NADH_4Fe-4S,SLBB
k141_2782_4	1348635.BBJY01000002_gene3425	7.54e-68	206.0	COG0347@1|root,COG0347@2|Bacteria,1RGWK@1224|Proteobacteria,1S67I@1236|Gammaproteobacteria,1XXCB@135623|Vibrionales	135623|Vibrionales	K	Belongs to the P(II) protein family	glnB	-	-	ko:K04751	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	P-II
k141_2782_5	675813.VIB_000684	5.48e-70	224.0	COG3021@1|root,COG3021@2|Bacteria,1MVPP@1224|Proteobacteria,1RMBH@1236|Gammaproteobacteria,1XTWA@135623|Vibrionales	135623|Vibrionales	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
k141_2782_6	55601.VANGNB10_cI2024	8.8e-235	662.0	COG0741@1|root,COG1388@1|root,COG0741@2|Bacteria,COG1388@2|Bacteria,1MWKE@1224|Proteobacteria,1RMFZ@1236|Gammaproteobacteria,1XUFQ@135623|Vibrionales	135623|Vibrionales	M	COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)	mltD	-	-	ko:K08307	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	LysM,SLT
k141_2782_7	945543.VIBR0546_19804	2.22e-125	363.0	COG0491@1|root,COG0491@2|Bacteria,1MU8Q@1224|Proteobacteria,1S22I@1236|Gammaproteobacteria,1XTAM@135623|Vibrionales	135623|Vibrionales	S	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid	gloB	GO:0003674,GO:0003824,GO:0004416,GO:0006518,GO:0006575,GO:0006749,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0016790,GO:0034641,GO:0043603,GO:0044237,GO:0051186,GO:0071704,GO:1901564	3.1.2.6	ko:K01069	ko00620,map00620	-	R01736	RC00004,RC00137	ko00000,ko00001,ko01000	-	-	-	HAGH_C,Lactamase_B
k141_2782_8	870967.VIS19158_17366	9.67e-138	394.0	COG0500@1|root,COG2226@2|Bacteria,1QTWC@1224|Proteobacteria,1RS4G@1236|Gammaproteobacteria,1XTUC@135623|Vibrionales	135623|Vibrionales	Q	COG0500 SAM-dependent methyltransferases	yafS	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
k141_2782_10	945543.VIBR0546_19789	2.82e-139	397.0	COG0847@1|root,COG0847@2|Bacteria,1MV8Z@1224|Proteobacteria,1RNHQ@1236|Gammaproteobacteria,1XTSV@135623|Vibrionales	135623|Vibrionales	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease	dnaQ	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	RNase_T
k141_2782_11	675815.VOA_002564	2.17e-171	493.0	COG2304@1|root,COG2304@2|Bacteria,1MVJ2@1224|Proteobacteria,1RMUF@1236|Gammaproteobacteria,1XSUT@135623|Vibrionales	135623|Vibrionales	S	von willebrand factor, type A	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_2782_12	1348635.BBJY01000002_gene3416	0.0	1011.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,1RPM5@1236|Gammaproteobacteria,1XTG6@135623|Vibrionales	135623|Vibrionales	I	COG1960 Acyl-CoA dehydrogenases	fadE	-	-	ko:K06445	ko00071,ko01100,ko01212,map00071,map01100,map01212	M00087	R01175,R01279,R03777,R03857,R03990,R04751,R04754	RC00052,RC00076	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_N,DUF1974
k141_2782_13	55601.VANGNB10_cI2017c	9.1e-118	338.0	COG0279@1|root,COG0279@2|Bacteria,1NVIE@1224|Proteobacteria,1RP6M@1236|Gammaproteobacteria,1XSJH@135623|Vibrionales	135623|Vibrionales	G	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate	gmhA	GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008968,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016853,GO:0016866,GO:0016868,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0046401,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509	5.3.1.28	ko:K03271	ko00540,ko01100,map00540,map01100	M00064	R05645,R09768,R09769	RC00434	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	SIS_2
k141_2782_14	1219076.N646_1393	9.58e-170	477.0	COG0121@1|root,COG0121@2|Bacteria,1MU1J@1224|Proteobacteria,1RNEK@1236|Gammaproteobacteria,1XTCN@135623|Vibrionales	135623|Vibrionales	S	glutamine amidotransferase	yafJ	-	-	-	-	-	-	-	-	-	-	-	GATase_4
k141_2782_15	243277.VC_2227	3.4e-121	349.0	COG0299@1|root,COG0299@2|Bacteria,1MWN1@1224|Proteobacteria,1RMHS@1236|Gammaproteobacteria,1XSWT@135623|Vibrionales	135623|Vibrionales	F	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate	purN	-	2.1.2.2	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	Formyl_trans_N
k141_2782_16	55601.VANGNB10_cI2014	4.03e-227	628.0	COG0150@1|root,COG0150@2|Bacteria,1MURG@1224|Proteobacteria,1RNZZ@1236|Gammaproteobacteria,1XSF7@135623|Vibrionales	135623|Vibrionales	F	Phosphoribosylformylglycinamidine cyclo-ligase	purM	GO:0003674,GO:0003824,GO:0004641,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016882,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
k141_2782_18	674977.VMC_09960	7.76e-91	272.0	COG2840@1|root,COG2840@2|Bacteria,1RH34@1224|Proteobacteria,1S6B5@1236|Gammaproteobacteria,1XT93@135623|Vibrionales	135623|Vibrionales	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	Smr
k141_2782_19	406817.XNC1_0399	1.54e-08	53.1	28Z00@1|root,2ZKSP@2|Bacteria,1P60B@1224|Proteobacteria,1SVSK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_2782_20	675815.VOA_002551	0.0	962.0	COG2217@1|root,COG2608@1|root,COG2217@2|Bacteria,COG2608@2|Bacteria,1MU08@1224|Proteobacteria,1RN2C@1236|Gammaproteobacteria,1XSZD@135623|Vibrionales	135623|Vibrionales	P	COG2217 Cation transport ATPase	copA	GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0051179,GO:0051234	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
k141_2782_21	1348635.BBJY01000002_gene3405	5.86e-298	818.0	COG0008@1|root,COG0008@2|Bacteria,1MUCR@1224|Proteobacteria,1RN3R@1236|Gammaproteobacteria,1XTNZ@135623|Vibrionales	135623|Vibrionales	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
k141_2782_22	243277.VC_2213	5e-114	340.0	COG2885@1|root,COG3637@1|root,COG2885@2|Bacteria,COG3637@2|Bacteria,1N6EM@1224|Proteobacteria,1SBXG@1236|Gammaproteobacteria,1XU00@135623|Vibrionales	135623|Vibrionales	M	Belongs to the ompA family	-	-	-	ko:K03286	-	-	-	-	ko00000,ko02000	1.B.6	-	-	OmpA,OmpA_membrane
k141_518_1	66692.ABC3804	9.69e-47	170.0	COG3209@1|root,COG5444@1|root,COG3209@2|Bacteria,COG5444@2|Bacteria,1V54A@1239|Firmicutes,4HI4F@91061|Bacilli	91061|Bacilli	M	nuclease activity	-	-	-	-	-	-	-	-	-	-	-	-	EndoU_bacteria
k141_518_2	1220589.CD32_12590	1.2e-17	78.6	2DI9P@1|root,302G7@2|Bacteria,1U39C@1239|Firmicutes,4IADA@91061|Bacilli,3J00I@400634|Lysinibacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_518_3	1005048.CFU_2247	1.55e-11	69.3	COG3210@1|root,COG3210@2|Bacteria,1MX2K@1224|Proteobacteria,2VI40@28216|Betaproteobacteria,472IR@75682|Oxalobacteraceae	28216|Betaproteobacteria	U	TIGRFAM adhesin HecA family 20-residue repeat (two copies), filamentous hemagglutinin family N-terminal domain	fhaB	-	-	ko:K15125	ko05133,map05133	-	-	-	ko00000,ko00001,ko00536	-	-	-	ESPR,Fil_haemagg,Fil_haemagg_2,Haemagg_act
k141_1145_1	1208321.D104_11675	1.24e-96	291.0	COG0697@1|root,COG0697@2|Bacteria,1RDQ0@1224|Proteobacteria,1SNBH@1236|Gammaproteobacteria	1236|Gammaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
k141_1145_3	525146.Ddes_0478	3.83e-39	144.0	COG3713@1|root,COG3713@2|Bacteria,1MWQN@1224|Proteobacteria,42W5N@68525|delta/epsilon subdivisions,2WSSS@28221|Deltaproteobacteria,2MC1U@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	MltA-interacting protein MipA	-	-	-	ko:K07274	-	-	-	-	ko00000,ko02000	9.B.99.1	-	-	MipA
k141_1145_4	575788.VS_II0065	2.45e-34	119.0	2E588@1|root,3300P@2|Bacteria,1N79I@1224|Proteobacteria,1SCYA@1236|Gammaproteobacteria,1XXZB@135623|Vibrionales	135623|Vibrionales	S	Domain of unknown function (DUF5062)	VVA0683	-	-	-	-	-	-	-	-	-	-	-	DUF5062
k141_1145_5	1225184.ALXE01000039_gene3041	3.7e-172	489.0	COG1902@1|root,COG1902@2|Bacteria,1MVE0@1224|Proteobacteria,1RMII@1236|Gammaproteobacteria,3VZDI@53335|Pantoea	1236|Gammaproteobacteria	C	NADH flavin oxidoreductase NADH oxidase	xenA	-	-	-	-	-	-	-	-	-	-	-	Oxidored_FMN
k141_1145_6	1353537.TP2_15325	4.21e-28	103.0	COG1359@1|root,COG1359@2|Bacteria	2|Bacteria	S	Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	ABM
k141_1145_7	316275.VSAL_II0079	9.73e-227	629.0	COG2866@1|root,COG2866@2|Bacteria,1MUMN@1224|Proteobacteria,1RQB4@1236|Gammaproteobacteria,1XU40@135623|Vibrionales	135623|Vibrionales	E	Zn_pept	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
k141_1145_8	1121918.ARWE01000001_gene2758	1.96e-244	681.0	COG0004@1|root,COG0004@2|Bacteria,1NR9F@1224|Proteobacteria,42M8M@68525|delta/epsilon subdivisions,2WJE2@28221|Deltaproteobacteria,43S70@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	Ammonium Transporter Family	-	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
k141_1823_1	1304875.JAFZ01000002_gene228	4.58e-50	174.0	COG0733@1|root,COG0733@2|Bacteria,3T9W5@508458|Synergistetes	508458|Synergistetes	P	Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family	-	-	-	ko:K03308	-	-	-	-	ko00000	2.A.22.4,2.A.22.5	-	-	SNF
k141_4168_1	575788.VS_0508	2.67e-214	603.0	COG1114@1|root,COG1114@2|Bacteria,1MVIF@1224|Proteobacteria,1RR3P@1236|Gammaproteobacteria,1XTP0@135623|Vibrionales	135623|Vibrionales	U	Component of the transport system for branched-chain amino acids	brnQ	-	-	ko:K03311	-	-	-	-	ko00000	2.A.26	-	-	Branch_AA_trans
k141_4168_2	1248232.BANQ01000008_gene1921	5.22e-68	217.0	COG4123@1|root,COG4123@2|Bacteria,1PC8R@1224|Proteobacteria,1RM8S@1236|Gammaproteobacteria,1XTHE@135623|Vibrionales	135623|Vibrionales	J	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)	yfiC	GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016426,GO:0016430,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.1.1.223	ko:K15460	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	MTS
k141_1824_1	439235.Dalk_2170	8.24e-10	64.7	COG0457@1|root,COG0457@2|Bacteria,1NFQW@1224|Proteobacteria,42MT2@68525|delta/epsilon subdivisions,2WKWA@28221|Deltaproteobacteria,2MJFK@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_2,TPR_4,TPR_8
k141_519_1	879212.DespoDRAFT_00845	5.03e-84	278.0	COG3829@1|root,COG3829@2|Bacteria,1N4M6@1224|Proteobacteria,42M38@68525|delta/epsilon subdivisions,2WIR0@28221|Deltaproteobacteria,2MJ85@213118|Desulfobacterales	28221|Deltaproteobacteria	T	sigma-54 factor interaction domain-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,PAS_4,PAS_9,Sigma54_activat
k141_2139_1	945543.VIBR0546_02675	1.97e-53	185.0	COG3209@1|root,COG3209@2|Bacteria,1PDT2@1224|Proteobacteria,1TEF8@1236|Gammaproteobacteria,1XZDG@135623|Vibrionales	135623|Vibrionales	M	COG3209 Rhs family protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_2139_3	1192034.CAP_8653	1.88e-26	117.0	COG3064@1|root,COG3209@1|root,COG3064@2|Bacteria,COG3209@2|Bacteria,1MVV1@1224|Proteobacteria,42R71@68525|delta/epsilon subdivisions,2WMW5@28221|Deltaproteobacteria,2Z1CW@29|Myxococcales	28221|Deltaproteobacteria	M	RHS Repeat	-	-	-	-	-	-	-	-	-	-	-	-	DUF4150,RHS,RHS_repeat,Transglut_core
k141_2139_4	211586.SO_1242	1.08e-35	127.0	2E6FJ@1|root,3312W@2|Bacteria,1N6YC@1224|Proteobacteria,1SCHK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_4558_1	672.VV93_v1c14100	1.2e-103	306.0	COG0551@1|root,COG0551@2|Bacteria,1RJ5B@1224|Proteobacteria,1S349@1236|Gammaproteobacteria,1XT3J@135623|Vibrionales	135623|Vibrionales	L	Zn-finger domain associated with topoisomerase type I	-	-	-	-	-	-	-	-	-	-	-	-	DUF2726
k141_4558_2	675815.VOA_000262	2.81e-186	523.0	COG0784@1|root,COG0835@1|root,COG0784@2|Bacteria,COG0835@2|Bacteria,1MXWK@1224|Proteobacteria,1S1EN@1236|Gammaproteobacteria,1XU3X@135623|Vibrionales	135623|Vibrionales	T	COG0835 Chemotaxis signal transduction protein	-	-	-	ko:K03415	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	CheW,Response_reg
k141_1848_2	675814.VIC_003221	1.41e-92	271.0	COG2199@1|root,COG3706@2|Bacteria,1MY91@1224|Proteobacteria,1S2IP@1236|Gammaproteobacteria,1XW7G@135623|Vibrionales	135623|Vibrionales	T	COG2202 FOG PAS PAC domain	-	-	-	-	-	-	-	-	-	-	-	-	PAS,PAS_4
k141_1848_3	945550.VISI1226_03870	2.18e-196	549.0	COG0784@1|root,COG1776@1|root,COG0784@2|Bacteria,COG1776@2|Bacteria,1P5BV@1224|Proteobacteria,1RN5X@1236|Gammaproteobacteria,1XUEQ@135623|Vibrionales	135623|Vibrionales	T	COG0784 FOG CheY-like receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
k141_1848_4	945550.VISI1226_09604	6.59e-42	137.0	COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,1SCA7@1236|Gammaproteobacteria,1XYCD@135623|Vibrionales	135623|Vibrionales	K	Cold shock	cspV	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
k141_1848_5	55601.VANGNB10_cII0834c	1.84e-132	384.0	COG0668@1|root,COG0668@2|Bacteria,1Q8BJ@1224|Proteobacteria,1S0HZ@1236|Gammaproteobacteria,1XUCI@135623|Vibrionales	135623|Vibrionales	M	Mechanosensitive ion channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel
k141_1848_6	675806.VII_000076	1.66e-213	599.0	COG2195@1|root,COG2195@2|Bacteria,1MV7D@1224|Proteobacteria,1RMKZ@1236|Gammaproteobacteria,1XTBU@135623|Vibrionales	135623|Vibrionales	E	Cleaves the N-terminal amino acid of tripeptides	pepT	GO:0003674,GO:0003824,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:0140096,GO:1901564	3.4.11.4	ko:K01258	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M42
k141_4902_1	1120970.AUBZ01000020_gene1387	1.87e-38	151.0	COG3850@1|root,COG3850@2|Bacteria,1MWZT@1224|Proteobacteria,1RNPP@1236|Gammaproteobacteria,465S0@72275|Alteromonadaceae	1236|Gammaproteobacteria	T	COG3850 Signal transduction histidine kinase, nitrate nitrite-specific	narQ	GO:0000155,GO:0000160,GO:0001101,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009987,GO:0010035,GO:0010167,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0035556,GO:0036211,GO:0042221,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0070887,GO:0071229,GO:0071241,GO:0071249,GO:0071250,GO:0071704,GO:0071944,GO:0080033,GO:0140096,GO:1901564,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902170	2.7.13.3	ko:K07673,ko:K07674	ko02020,map02020	M00471,M00472	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA_3,PilJ
k141_2435_1	667014.Thein_1261	2.24e-23	103.0	COG0116@1|root,COG0116@2|Bacteria,2GIGM@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	L	THUMP domain	-	-	-	ko:K07444	-	-	-	-	ko00000,ko01000	-	-	-	THUMP,UPF0020
k141_4579_1	425104.Ssed_0629	1.08e-85	290.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,2QAY1@267890|Shewanellaceae	1236|Gammaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	czcA	-	-	ko:K18138	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
k141_2798_1	340177.Cag_0614	1.68e-108	392.0	COG1357@1|root,COG2931@1|root,COG3210@1|root,COG4625@1|root,COG1357@2|Bacteria,COG2931@2|Bacteria,COG3210@2|Bacteria,COG4625@2|Bacteria	2|Bacteria	T	pathogenesis	rhgB	-	4.2.2.23	ko:K07004,ko:K18195	-	-	-	-	ko00000,ko01000	-	PL4	-	CBM-like,RhgB_N,fn3_3
k141_4903_1	177437.HRM2_26830	1.03e-79	268.0	COG0449@1|root,COG0449@2|Bacteria,1MW4K@1224|Proteobacteria,42KZ7@68525|delta/epsilon subdivisions,2WJP6@28221|Deltaproteobacteria,2MIWZ@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	iAF987.Gmet_1487	GATase_6,SIS
k141_2156_1	318167.Sfri_0689	3.93e-35	126.0	COG2964@1|root,COG2964@2|Bacteria,1MU5K@1224|Proteobacteria,1RPDQ@1236|Gammaproteobacteria,2QEER@267890|Shewanellaceae	1236|Gammaproteobacteria	S	PFAM YheO domain protein	Z012_06050	-	-	-	-	-	-	-	-	-	-	-	HTH_22,PAS_6
k141_2156_3	7213.XP_004531885.1	1.18e-32	126.0	COG0494@1|root,KOG3069@2759|Eukaryota,3A1ZV@33154|Opisthokonta,3BQTU@33208|Metazoa,3D3DX@33213|Bilateria	33208|Metazoa	L	coenzyme A catabolic process	NUDT7	GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0003986,GO:0004778,GO:0005102,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0006084,GO:0006139,GO:0006163,GO:0006195,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009109,GO:0009117,GO:0009150,GO:0009154,GO:0009166,GO:0009259,GO:0009261,GO:0009987,GO:0015936,GO:0015938,GO:0016289,GO:0016787,GO:0016788,GO:0016790,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0030154,GO:0030515,GO:0032502,GO:0033865,GO:0033869,GO:0033875,GO:0034031,GO:0034032,GO:0034034,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035383,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044273,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045444,GO:0046356,GO:0046434,GO:0046483,GO:0046700,GO:0047994,GO:0048869,GO:0050873,GO:0051186,GO:0051187,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0097159,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901576	-	ko:K17879	ko04146,map04146	-	R10747	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
k141_2156_4	1517681.HW45_03785	5.65e-276	762.0	COG2433@1|root,COG2433@2|Bacteria,1QYSX@1224|Proteobacteria,1RX8U@1236|Gammaproteobacteria,1Y2AV@135623|Vibrionales	135623|Vibrionales	S	Transposase IS66 family	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS66
k141_2156_7	617140.AJZE01000035_gene3254	3.54e-91	270.0	COG3028@1|root,COG3028@2|Bacteria,1MZ4R@1224|Proteobacteria,1S9JJ@1236|Gammaproteobacteria,1XTXV@135623|Vibrionales	135623|Vibrionales	S	Belongs to the UPF0307 family	yjgA	-	-	ko:K09889	-	-	-	-	ko00000,ko03009	-	-	-	DUF615
k141_3179_1	1121405.dsmv_2833	9.31e-170	509.0	COG0249@1|root,COG0249@2|Bacteria,1MUGX@1224|Proteobacteria,42MRR@68525|delta/epsilon subdivisions,2WIQ7@28221|Deltaproteobacteria,2MIGW@213118|Desulfobacterales	28221|Deltaproteobacteria	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	mutS	GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
k141_4580_1	999415.HMPREF9943_00848	3.89e-30	126.0	COG0210@1|root,COG0210@2|Bacteria,1TPSU@1239|Firmicutes,3VPIN@526524|Erysipelotrichia	526524|Erysipelotrichia	L	DNA helicase	pcrA	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
k141_1849_2	1217705.F900_00373	3.9e-36	127.0	2BY0C@1|root,33B06@2|Bacteria,1P4DM@1224|Proteobacteria,1RSSC@1236|Gammaproteobacteria,3NRMC@468|Moraxellaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_1849_3	1121287.AUMU01000021_gene582	2.05e-15	73.2	2E9I2@1|root,333R4@2|Bacteria,4NV49@976|Bacteroidetes,1I5SY@117743|Flavobacteriia,3ZTXA@59732|Chryseobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_1849_4	243090.RB1597	6.9e-23	92.0	COG5113@1|root,COG3236@2|Bacteria,2IZ8E@203682|Planctomycetes	203682|Planctomycetes	O	Domain of unknown function (DUF1768)	-	-	-	ko:K09935	-	-	-	-	ko00000	-	-	-	DUF1768
k141_4904_1	933262.AXAM01000121_gene2	5.57e-35	124.0	COG0673@1|root,COG0673@2|Bacteria,1PDZZ@1224|Proteobacteria,42M63@68525|delta/epsilon subdivisions,2WJDW@28221|Deltaproteobacteria,2MJCU@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	ADH_zinc_N,GFO_IDH_MocA
k141_4904_2	468059.AUHA01000002_gene1160	3.45e-84	266.0	COG1331@1|root,COG1331@2|Bacteria,4NIPN@976|Bacteroidetes	976|Bacteroidetes	O	Highly conserved protein containing a thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_88
k141_4581_1	574966.KB898646_gene2790	1.76e-65	214.0	COG0463@1|root,COG0463@2|Bacteria,1MWE5@1224|Proteobacteria,1RPCE@1236|Gammaproteobacteria,1XJ14@135619|Oceanospirillales	135619|Oceanospirillales	M	glycosyl transferase family 2	-	-	-	ko:K20534	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.2.1.9	GT2	-	Glycos_transf_2
k141_5168_3	1348635.BBJY01000013_gene1064	3.99e-315	865.0	COG0388@1|root,COG0388@2|Bacteria,1MX4I@1224|Proteobacteria,1RP30@1236|Gammaproteobacteria,1XUX9@135623|Vibrionales	135623|Vibrionales	S	Carbon-nitrogen hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,CN_hydrolase
k141_5168_4	999141.GME_06380	4.13e-65	209.0	COG0745@1|root,COG0745@2|Bacteria,1MY3D@1224|Proteobacteria,1RPKN@1236|Gammaproteobacteria,1XJDT@135619|Oceanospirillales	135619|Oceanospirillales	T	transcriptional regulator	-	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
k141_5168_5	55601.VANGNB10_cI0972	3.48e-219	619.0	COG0642@1|root,COG2205@2|Bacteria,1MUAK@1224|Proteobacteria,1RPP2@1236|Gammaproteobacteria,1XU4B@135623|Vibrionales	135623|Vibrionales	T	Signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
k141_5168_6	55601.VANGNB10_cI0973	2.44e-180	515.0	COG1653@1|root,COG1653@2|Bacteria,1MUYE@1224|Proteobacteria,1RRFK@1236|Gammaproteobacteria,1XSZM@135623|Vibrionales	135623|Vibrionales	G	COG1653 ABC-type sugar transport system, periplasmic component	-	-	-	ko:K17315	ko02010,map02010	M00605	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.24,3.A.1.1.30	-	-	SBP_bac_1,SBP_bac_8
k141_5168_7	945550.VISI1226_17645	5.57e-254	703.0	COG0544@1|root,COG0544@2|Bacteria,1MUJP@1224|Proteobacteria,1RNZE@1236|Gammaproteobacteria,1XUKH@135623|Vibrionales	135623|Vibrionales	D	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006457,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0071704,GO:0140096,GO:1901564	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C,Trigger_N
k141_5168_9	55601.VANGNB10_cI0982	4.7e-283	776.0	COG1219@1|root,COG1219@2|Bacteria,1MVQK@1224|Proteobacteria,1RN9N@1236|Gammaproteobacteria,1XUMV@135623|Vibrionales	135623|Vibrionales	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
k141_5168_10	675806.VII_001901	0.0	1294.0	COG0466@1|root,COG0466@2|Bacteria,1MUV2@1224|Proteobacteria,1RPCB@1236|Gammaproteobacteria,1XU6N@135623|Vibrionales	135623|Vibrionales	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
k141_4582_1	1319815.HMPREF0202_00128	1.41e-76	243.0	COG2182@1|root,COG2182@2|Bacteria,37CDV@32066|Fusobacteria	32066|Fusobacteria	G	Bacterial extracellular solute-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_8
k141_4905_1	1120999.JONM01000002_gene606	3.69e-13	71.6	COG0834@1|root,COG0834@2|Bacteria,1RCP2@1224|Proteobacteria,2VR5B@28216|Betaproteobacteria,2KRDP@206351|Neisseriales	206351|Neisseriales	ET	Bacterial extracellular solute-binding proteins, family 3	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_3
k141_4905_2	1121434.AULY01000007_gene1094	9.25e-18	84.0	COG1284@1|root,COG1284@2|Bacteria,1R3UZ@1224|Proteobacteria,42P9H@68525|delta/epsilon subdivisions,2WIUG@28221|Deltaproteobacteria,2M9TX@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Uncharacterised 5xTM membrane BCR, YitT family COG1284	-	-	-	-	-	-	-	-	-	-	-	-	DUF2179,YitT_membrane
k141_2158_1	349161.Dred_3125	4.68e-24	99.4	COG2963@1|root,COG2963@2|Bacteria,1V3YT@1239|Firmicutes,24ICX@186801|Clostridia	186801|Clostridia	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Tnp_1
k141_2158_2	1485545.JQLW01000010_gene1491	7.71e-127	374.0	COG2801@1|root,COG2801@2|Bacteria,1PBHA@1224|Proteobacteria	1224|Proteobacteria	L	Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	HTH_23,HTH_32,rve,rve_3
k141_2436_2	660470.Theba_2520	4.78e-26	111.0	COG1262@1|root,COG1262@2|Bacteria,2GEAZ@200918|Thermotogae	200918|Thermotogae	O	PFAM Formylglycine-generating sulfatase enzyme	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,PDZ_2
k141_1158_1	1219065.VPR01S_05_02100	2.59e-92	271.0	COG2131@1|root,COG2131@2|Bacteria,1NC75@1224|Proteobacteria,1S1U2@1236|Gammaproteobacteria,1XU6F@135623|Vibrionales	135623|Vibrionales	F	deoxycytidylate deaminase	-	-	3.5.4.12	ko:K01493	ko00240,ko01100,map00240,map01100	M00429	R01663	RC00074	ko00000,ko00001,ko00002,ko01000,ko02044	-	-	-	dCMP_cyt_deam_1
k141_1158_2	55601.VANGNB10_cII0187	5.71e-243	711.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,1RPRH@1236|Gammaproteobacteria,1XSQZ@135623|Vibrionales	135623|Vibrionales	T	COG0642 Signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,Response_reg
k141_1158_3	945550.VISI1226_03640	1.46e-27	107.0	COG0226@1|root,COG0226@2|Bacteria,1N5JQ@1224|Proteobacteria,1S942@1236|Gammaproteobacteria,1XSEH@135623|Vibrionales	135623|Vibrionales	P	Part of the ABC transporter complex PstSACB involved in phosphate import	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_1158_4	945550.VISI1226_03635	7.6e-90	280.0	COG3203@1|root,COG3203@2|Bacteria,1Q1XX@1224|Proteobacteria,1RPIH@1236|Gammaproteobacteria,1XU0K@135623|Vibrionales	135623|Vibrionales	M	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane	VP1757	-	-	-	-	-	-	-	-	-	-	-	Porin_4
k141_1158_5	55601.VANGNB10_cII0184	3.21e-85	257.0	COG1280@1|root,COG1280@2|Bacteria,1RDPB@1224|Proteobacteria,1S5JJ@1236|Gammaproteobacteria,1XTFX@135623|Vibrionales	135623|Vibrionales	E	threonine efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	LysE
k141_1158_6	411474.COPEUT_00343	1.85e-91	281.0	COG1533@1|root,COG1533@2|Bacteria,1TQA6@1239|Firmicutes,24A2T@186801|Clostridia	186801|Clostridia	L	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF1848
k141_1158_7	572477.Alvin_1203	3.91e-77	243.0	COG0157@1|root,COG0157@2|Bacteria,1MW0C@1224|Proteobacteria,1RMBU@1236|Gammaproteobacteria,1WXDB@135613|Chromatiales	135613|Chromatiales	H	Belongs to the NadC ModD family	-	-	-	ko:K03813	-	-	-	-	ko00000,ko01000	-	-	-	QRPTase_C,QRPTase_N
k141_1158_8	1524467.IV04_22170	9.98e-94	288.0	COG2988@1|root,COG2988@2|Bacteria,1MW1T@1224|Proteobacteria,1RQPG@1236|Gammaproteobacteria,400A1@613|Serratia	1236|Gammaproteobacteria	E	Belongs to the AspA AstE family. Succinylglutamate desuccinylase subfamily	astE	GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006807,GO:0008150,GO:0008152,GO:0009017,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016787,GO:0016810,GO:0016811,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	3.5.1.96	ko:K05526	ko00330,ko01100,map00330,map01100	-	R00411	RC00064,RC00090	ko00000,ko00001,ko01000	-	-	-	AstE_AspA
k141_1158_9	1348635.BBJY01000003_gene3860	7.11e-219	615.0	COG3724@1|root,COG3724@2|Bacteria,1MUJV@1224|Proteobacteria,1RNSS@1236|Gammaproteobacteria,1XVMD@135623|Vibrionales	135623|Vibrionales	E	Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2)	astB	-	3.5.3.23	ko:K01484	ko00330,ko01100,map00330,map01100	-	R04189	RC00024	ko00000,ko00001,ko01000	-	-	-	AstB
k141_1158_10	345073.VC395_A0071	9.63e-276	768.0	COG0659@1|root,COG0659@2|Bacteria,1MVWV@1224|Proteobacteria,1RMCN@1236|Gammaproteobacteria,1XW6V@135623|Vibrionales	135623|Vibrionales	P	COG0659 Sulfate permease and related transporters (MFS superfamily)	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
k141_2799_1	1232437.KL662077_gene1866	1.23e-120	360.0	COG4799@1|root,COG4799@2|Bacteria,1MVAX@1224|Proteobacteria,43AEE@68525|delta/epsilon subdivisions,2WIRF@28221|Deltaproteobacteria,2MIPI@213118|Desulfobacterales	28221|Deltaproteobacteria	I	PFAM carboxyl transferase	-	-	2.1.3.1,2.1.3.15,6.4.1.3	ko:K01966,ko:K17489	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	M00373,M00741	R00353,R01859	RC00040,RC00097,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
k141_2799_2	87626.PTD2_07289	1.66e-19	96.7	COG0642@1|root,COG3614@1|root,COG0642@2|Bacteria,COG2205@2|Bacteria,COG3614@2|Bacteria,1NRP8@1224|Proteobacteria,1SKTW@1236|Gammaproteobacteria,2Q5GD@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	T	PAS domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_3,HATPase_c,HisKA,Hpt,PAS_3,PAS_9,Response_reg
k141_2799_3	1307759.JOMJ01000003_gene1595	5.68e-05	51.2	COG0727@1|root,COG0727@2|Bacteria,1REPM@1224|Proteobacteria,42RPZ@68525|delta/epsilon subdivisions,2WNSE@28221|Deltaproteobacteria,2M9RI@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Putative zinc- or iron-chelating domain	-	-	-	-	-	-	-	-	-	-	-	-	CxxCxxCC
k141_2575_4	177437.HRM2_25460	3.09e-113	340.0	COG1086@1|root,COG2148@1|root,COG1086@2|Bacteria,COG2148@2|Bacteria,1MV6W@1224|Proteobacteria,42MZY@68525|delta/epsilon subdivisions,2WJWT@28221|Deltaproteobacteria,2MHW0@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Bacterial sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf,CoA_binding_3
k141_636_1	1528106.JRJE01000005_gene1302	7.83e-115	348.0	COG0733@1|root,COG0733@2|Bacteria,1MUZJ@1224|Proteobacteria,2TUE5@28211|Alphaproteobacteria,2JPSJ@204441|Rhodospirillales	204441|Rhodospirillales	S	Sodium:neurotransmitter symporter family	-	-	-	ko:K03308	-	-	-	-	ko00000	2.A.22.4,2.A.22.5	-	-	SNF
k141_636_2	1123368.AUIS01000016_gene2554	2.43e-12	67.0	COG2199@1|root,COG2199@2|Bacteria,1QWGR@1224|Proteobacteria,1T3HC@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	COG2199 FOG GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
k141_2894_1	1348635.BBJY01000006_gene489	4.91e-50	167.0	COG0583@1|root,COG0583@2|Bacteria,1MVJ7@1224|Proteobacteria,1RMNJ@1236|Gammaproteobacteria,1Y0A5@135623|Vibrionales	135623|Vibrionales	K	Bacterial regulatory helix-turn-helix protein, lysR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
k141_2894_2	1348635.BBJY01000006_gene490	1.79e-69	218.0	COG0730@1|root,COG0730@2|Bacteria,1MXNM@1224|Proteobacteria,1RRH4@1236|Gammaproteobacteria,1XSXB@135623|Vibrionales	135623|Vibrionales	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
k141_3696_1	985054.JQEZ01000004_gene706	4.53e-07	53.5	COG2199@1|root,COG2208@1|root,COG2208@2|Bacteria,COG3706@2|Bacteria,1N4K5@1224|Proteobacteria,2TS77@28211|Alphaproteobacteria,4N9Z4@97050|Ruegeria	28211|Alphaproteobacteria	T	response regulator	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	HATPase_c_2,Response_reg,SpoIIE
k141_3696_2	1187848.AJYQ01000075_gene1605	1.16e-15	75.5	2A6R1@1|root,30VJ5@2|Bacteria,1RGD8@1224|Proteobacteria,1S593@1236|Gammaproteobacteria,1XSR7@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_4303_3	272563.CD630_33090	2.05e-277	783.0	COG0272@1|root,COG0272@2|Bacteria,1TPQ3@1239|Firmicutes,248AX@186801|Clostridia,25R5S@186804|Peptostreptococcaceae	186801|Clostridia	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	-	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
k141_4303_7	1169144.KB910957_gene3880	2.14e-79	243.0	COG1136@1|root,COG1136@2|Bacteria,1V3NN@1239|Firmicutes,4HI0Q@91061|Bacilli,1ZGVP@1386|Bacillus	91061|Bacilli	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003,ko:K09810	ko02010,map02010	M00255,M00258	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1,3.A.1.125	-	-	ABC_tran
k141_4303_8	315749.Bcer98_1389	2.87e-75	265.0	COG4652@1|root,COG4652@2|Bacteria,1V0A8@1239|Firmicutes,4HI0H@91061|Bacilli,1ZDTD@1386|Bacillus	91061|Bacilli	S	Protein of unknown function (DUF1430)	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	DUF1430
k141_4303_9	1294142.CINTURNW_1213	2.39e-63	213.0	COG0491@1|root,COG2119@1|root,COG0491@2|Bacteria,COG2119@2|Bacteria,1UFX2@1239|Firmicutes,24DHF@186801|Clostridia,36HDQ@31979|Clostridiaceae	186801|Clostridia	S	Uncharacterized protein family UPF0016	-	-	-	-	-	-	-	-	-	-	-	-	UPF0016
k141_4303_11	926692.AZYG01000054_gene2299	7.23e-18	92.8	COG0840@1|root,COG0840@2|Bacteria,1TP5A@1239|Firmicutes,247S3@186801|Clostridia,3WB5H@53433|Halanaerobiales	186801|Clostridia	NT	Cache domain	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal,dCache_1,sCache_2
k141_4303_12	1087481.AGFX01000018_gene1757	7.33e-140	442.0	COG5373@1|root,COG5373@2|Bacteria,1UUGX@1239|Firmicutes,4IRFV@91061|Bacilli	91061|Bacilli	S	Predicted membrane protein (DUF2339)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2339
k141_4303_16	1395513.P343_08435	4.46e-42	145.0	COG3981@1|root,COG3981@2|Bacteria,1V1C4@1239|Firmicutes,4HG6C@91061|Bacilli	91061|Bacilli	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_3
k141_4303_17	1291050.JAGE01000002_gene3440	2.64e-38	132.0	COG0853@1|root,COG0853@2|Bacteria,1V6NQ@1239|Firmicutes,24JVN@186801|Clostridia,3WJM9@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine	panD	-	4.1.1.11	ko:K01579	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R00489	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Asp_decarbox
k141_4303_18	545697.HMPREF0216_00480	6.11e-88	271.0	COG0414@1|root,COG0414@2|Bacteria,1TP7A@1239|Firmicutes,248AN@186801|Clostridia,36E8S@31979|Clostridiaceae	186801|Clostridia	H	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate	panC	-	6.3.2.1	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R02473	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_ligase
k141_4303_19	1151292.QEW_1921	5.02e-112	331.0	COG0413@1|root,COG0413@2|Bacteria,1TPZA@1239|Firmicutes,248RR@186801|Clostridia	186801|Clostridia	H	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate	panB	-	2.1.2.11	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R01226	RC00022,RC00200	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_transf
k141_4303_20	997350.HMPREF9129_0057	2.37e-43	156.0	COG5495@1|root,COG5495@2|Bacteria,1UZZU@1239|Firmicutes,249YF@186801|Clostridia	186801|Clostridia	S	NADP oxidoreductase coenzyme F420-dependent	-	-	-	-	-	-	-	-	-	-	-	-	DUF2520,F420_oxidored,Rossmann-like
k141_4303_21	1094466.KQS_12710	6.46e-59	193.0	COG0670@1|root,COG0670@2|Bacteria,4NG98@976|Bacteroidetes,1I1C3@117743|Flavobacteriia	976|Bacteroidetes	S	Inhibitor of apoptosis-promoting Bax1	ybhL	-	-	ko:K06890	-	-	-	-	ko00000	-	-	-	Bax1-I
k141_4303_22	1321778.HMPREF1982_01729	1.58e-66	225.0	COG0477@1|root,COG2814@2|Bacteria,1TQDU@1239|Firmicutes,25ESY@186801|Clostridia	186801|Clostridia	EGP	Major Facilitator	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
k141_3697_1	1265505.ATUG01000003_gene622	5.85e-115	366.0	COG0493@1|root,COG1148@1|root,COG0493@2|Bacteria,COG1148@2|Bacteria,1QUM4@1224|Proteobacteria,42MPP@68525|delta/epsilon subdivisions,2WJ3U@28221|Deltaproteobacteria,2MIA4@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_20,Pyr_redox_2
k141_2323_1	380358.XALC_2860	6.63e-07	55.5	COG0758@1|root,COG0758@2|Bacteria,1MVF6@1224|Proteobacteria,1RPJE@1236|Gammaproteobacteria,1X2Y5@135614|Xanthomonadales	135614|Xanthomonadales	LU	DNA processing protein DprA	smf	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A
k141_2323_2	1304885.AUEY01000019_gene1160	7.23e-123	375.0	COG0550@1|root,COG0550@2|Bacteria,1MUFZ@1224|Proteobacteria,42MM9@68525|delta/epsilon subdivisions,2WJTT@28221|Deltaproteobacteria,2MITA@213118|Desulfobacterales	28221|Deltaproteobacteria	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,zf-C4_Topoisom
k141_637_1	755731.Clo1100_2834	2.12e-55	182.0	COG1186@1|root,COG1186@2|Bacteria,1V4FM@1239|Firmicutes,24HBK@186801|Clostridia,36JRR@31979|Clostridiaceae	186801|Clostridia	J	RF-1 domain	-	-	-	ko:K02839	-	-	-	-	ko00000,ko03012	-	-	-	RF-1
k141_637_2	1267005.KB911265_gene3614	4.24e-23	98.2	COG1690@1|root,COG1690@2|Bacteria,1MUHA@1224|Proteobacteria,2TTUE@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	release factor H-coupled RctB family protein	-	-	6.5.1.3	ko:K14415,ko:K18148	ko01501,map01501	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	RtcB
k141_2895_1	305900.GV64_17195	6.92e-30	113.0	COG0645@1|root,COG0645@2|Bacteria,1RHF4@1224|Proteobacteria,1S3QW@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_33
k141_2895_2	1280694.AUJQ01000004_gene418	4.88e-17	84.3	COG3884@1|root,COG3884@2|Bacteria,1TRH5@1239|Firmicutes,24G5K@186801|Clostridia,3NGDZ@46205|Pseudobutyrivibrio	186801|Clostridia	I	Acyl-ACP thioesterase	-	-	3.1.2.21	ko:K01071	ko00061,ko01100,map00061,map01100	-	R04014,R08157,R08158	RC00014,RC00039	ko00000,ko00001,ko01000,ko01004	-	-	-	Acyl-ACP_TE
k141_4719_1	1121090.KB894691_gene2582	5.66e-05	53.5	COG0388@1|root,COG0388@2|Bacteria,1UVVD@1239|Firmicutes,4IE1Z@91061|Bacilli,1ZCNN@1386|Bacillus	91061|Bacilli	S	Carbon-nitrogen hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	CN_hydrolase
k141_638_1	672.VV93_v1c33000	2e-93	275.0	COG3040@1|root,COG3040@2|Bacteria,1RDAI@1224|Proteobacteria,1S3PW@1236|Gammaproteobacteria,1XXE6@135623|Vibrionales	135623|Vibrionales	M	lipoprotein Blc	blc	-	-	ko:K03098	-	-	-	-	ko00000,ko04147	-	-	-	Lipocalin_2
k141_2576_1	1265505.ATUG01000001_gene4349	1.68e-111	331.0	COG0745@1|root,COG2197@1|root,COG0745@2|Bacteria,COG2197@2|Bacteria	2|Bacteria	K	response regulator	-	-	-	ko:K02282,ko:K07782,ko:K19135	ko02020,ko02024,ko02026,map02020,map02024,map02026	-	-	-	ko00000,ko00001,ko02035,ko02044,ko02048,ko03000	-	-	-	Cas_NE0113,GerE,Response_reg
k141_2576_2	485918.Cpin_5863	1.26e-06	60.5	COG1470@1|root,COG2931@1|root,COG4886@1|root,COG4932@1|root,COG5492@1|root,COG1470@2|Bacteria,COG2931@2|Bacteria,COG4886@2|Bacteria,COG4932@2|Bacteria,COG5492@2|Bacteria,4PMF3@976|Bacteroidetes,1IT6W@117747|Sphingobacteriia	976|Bacteroidetes	N	PFAM Bacterial Ig-like domain (group 2)	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,CHU_C,VCBS
k141_2326_1	349521.HCH_05019	4.1e-74	230.0	2C03A@1|root,2Z86B@2|Bacteria,1REIV@1224|Proteobacteria,1S4UW@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Domain of unknown function (DUF4291)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4291
k141_2326_2	1242864.D187_002582	8.2e-112	327.0	COG1051@1|root,COG1051@2|Bacteria,1QTT4@1224|Proteobacteria,42SX4@68525|delta/epsilon subdivisions,2WPWK@28221|Deltaproteobacteria,2YY1W@29|Myxococcales	28221|Deltaproteobacteria	F	Belongs to the Nudix hydrolase family	-	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
k141_4722_1	1121396.KB893087_gene381	4.86e-50	172.0	COG0598@1|root,COG0598@2|Bacteria,1MX09@1224|Proteobacteria,42NS9@68525|delta/epsilon subdivisions,2WJMJ@28221|Deltaproteobacteria,2MI8N@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Mediates influx of magnesium ions	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
k141_641_1	936375.HMPREF1152_1826	3.39e-29	119.0	COG2890@1|root,COG3872@1|root,COG2890@2|Bacteria,COG3872@2|Bacteria,1TPBU@1239|Firmicutes,25C8E@186801|Clostridia,3WD2N@538999|Clostridiales incertae sedis	186801|Clostridia	J	Protein of unknown function (DUF1385)	prmC	-	-	-	-	-	-	-	-	-	-	-	DUF1385,MTS
k141_641_2	96561.Dole_0474	3.06e-21	89.7	COG0052@1|root,COG0052@2|Bacteria,1MU33@1224|Proteobacteria,42M3Y@68525|delta/epsilon subdivisions,2WJH5@28221|Deltaproteobacteria,2MJCG@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Belongs to the universal ribosomal protein uS2 family	rpsB	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
k141_2897_1	631362.Thi970DRAFT_01670	4.18e-188	567.0	COG2274@1|root,COG2274@2|Bacteria,1MY50@1224|Proteobacteria,1S02I@1236|Gammaproteobacteria,1X2CU@135613|Chromatiales	1236|Gammaproteobacteria	V	TIGRFAM NHLM bacteriocin system ABC transporter, ATP-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC_membrane,ABC_tran
k141_1291_1	55601.VANGNB10_cI2662c	1.12e-45	155.0	2AW95@1|root,31N4G@2|Bacteria,1QJVY@1224|Proteobacteria,1THXK@1236|Gammaproteobacteria,1XXUB@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_1291_3	1348635.BBJY01000016_gene3976	8.25e-127	370.0	COG0697@1|root,COG0697@2|Bacteria,1QSKQ@1224|Proteobacteria,1RYG1@1236|Gammaproteobacteria,1XV0H@135623|Vibrionales	135623|Vibrionales	EG	of the drug metabolite transporter (DMT) superfamily	-	-	-	-	-	-	-	-	-	-	-	-	EamA
k141_1291_4	55601.VANGNB10_cI2659c	5.19e-225	637.0	COG1322@1|root,COG1322@2|Bacteria,1MWHV@1224|Proteobacteria,1RMB8@1236|Gammaproteobacteria,1XV2P@135623|Vibrionales	135623|Vibrionales	S	dna recombination protein rmuc	rmuC	-	-	ko:K09760	-	-	-	-	ko00000	-	-	-	RmuC
k141_1291_5	243277.VC_0083	5.5e-170	476.0	COG0500@1|root,COG2226@2|Bacteria,1MX8I@1224|Proteobacteria,1RMAU@1236|Gammaproteobacteria,1XSR2@135623|Vibrionales	135623|Vibrionales	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2)	ubiE	GO:0003674,GO:0003824,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008168,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0016740,GO:0016741,GO:0032259,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
k141_1291_6	223926.28805078	1.8e-85	258.0	COG3165@1|root,COG3165@2|Bacteria,1R1CM@1224|Proteobacteria,1S745@1236|Gammaproteobacteria,1XUNJ@135623|Vibrionales	135623|Vibrionales	S	protein conserved in bacteria	-	-	-	ko:K03690	-	-	-	-	ko00000	-	-	-	SCP2
k141_1291_7	55601.VANGNB10_cI2656c	0.0	907.0	COG0661@1|root,COG0661@2|Bacteria,1MU1Z@1224|Proteobacteria,1RNQM@1236|Gammaproteobacteria,1XSB2@135623|Vibrionales	135623|Vibrionales	H	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis	ubiB	GO:0003674,GO:0003824,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663	-	ko:K03688	-	-	-	-	ko00000	-	-	-	ABC1
k141_1291_8	796620.VIBC2010_02935	1.43e-140	401.0	COG0084@1|root,COG0084@2|Bacteria,1MUC0@1224|Proteobacteria,1SPRE@1236|Gammaproteobacteria,1XUSU@135623|Vibrionales	135623|Vibrionales	L	COG0084 Mg-dependent DNase	tatD	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
k141_1291_9	29495.EA26_01285	3.95e-217	603.0	COG0113@1|root,COG0113@2|Bacteria,1MWMW@1224|Proteobacteria,1RP6Q@1236|Gammaproteobacteria,1XSJ4@135623|Vibrionales	135623|Vibrionales	H	Belongs to the ALAD family	hemB	-	4.2.1.24	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00036	RC00918,RC01781	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ALAD
k141_1291_10	1280001.BAOA01000051_gene1544	0.0	1420.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,1RNBG@1236|Gammaproteobacteria,1XUAZ@135623|Vibrionales	135623|Vibrionales	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
k141_4987_2	223926.28806972	0.0	1267.0	COG1032@1|root,COG1032@2|Bacteria,1MUG3@1224|Proteobacteria,1RN9V@1236|Gammaproteobacteria,1XT35@135623|Vibrionales	135623|Vibrionales	C	UPF0313 protein	ygiQ	-	-	-	-	-	-	-	-	-	-	-	DUF3362,Radical_SAM,Radical_SAM_N
k141_4987_4	342113.DM82_1197	2.04e-09	59.7	2DIDI@1|root,302W6@2|Bacteria,1PYUW@1224|Proteobacteria,2WDZA@28216|Betaproteobacteria,1KBAR@119060|Burkholderiaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_4987_5	243277.VC_1708	1.2e-48	166.0	2E04S@1|root,32VT8@2|Bacteria,1N3T4@1224|Proteobacteria,1SBN3@1236|Gammaproteobacteria,1XTHM@135623|Vibrionales	135623|Vibrionales	-	-	VV2139	-	-	-	-	-	-	-	-	-	-	-	-
k141_4987_6	1056512.D515_00015	1e-16	73.6	2EG1V@1|root,339TV@2|Bacteria,1NI0B@1224|Proteobacteria,1SGIA@1236|Gammaproteobacteria,1XYCW@135623|Vibrionales	135623|Vibrionales	S	Domain of unknown function (DUF4250)	VC1707	-	-	-	-	-	-	-	-	-	-	-	DUF4250
k141_4987_7	1370122.JHXQ01000006_gene955	5.87e-33	120.0	COG1522@1|root,COG1522@2|Bacteria,1RHI9@1224|Proteobacteria,2UBWP@28211|Alphaproteobacteria,4B92J@82115|Rhizobiaceae	28211|Alphaproteobacteria	K	helix_turn_helix ASNC type	-	-	-	ko:K03719	-	-	-	-	ko00000,ko03000,ko03036	-	-	-	AsnC_trans_reg,HTH_24,HTH_AsnC-type
k141_642_1	177437.HRM2_25160	6.49e-25	103.0	COG0529@1|root,COG2046@1|root,COG0529@2|Bacteria,COG2046@2|Bacteria,1MUQB@1224|Proteobacteria,43BR1@68525|delta/epsilon subdivisions,2WIIS@28221|Deltaproteobacteria,2MIQ9@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Catalyzes the synthesis of activated sulfate	cysC	-	2.7.7.4	ko:K00958	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R04929	RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase,ATP-sulfurylase,PUA_2
k141_642_2	319225.Plut_1663	9.17e-43	145.0	COG1661@1|root,COG1661@2|Bacteria,1FFCY@1090|Chlorobi	1090|Chlorobi	S	Domain of unknown function (DUF296)	-	-	-	ko:K06934	-	-	-	-	ko00000	-	-	-	DUF296
k141_3699_1	1121405.dsmv_3650	1.12e-88	264.0	COG0250@1|root,COG0250@2|Bacteria,1MU14@1224|Proteobacteria,42MPQ@68525|delta/epsilon subdivisions,2WMP6@28221|Deltaproteobacteria,2MHS4@213118|Desulfobacterales	28221|Deltaproteobacteria	K	Participates in transcription elongation, termination and antitermination	nusG	-	-	ko:K02601	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KOW,NusG
k141_3699_2	1499967.BAYZ01000113_gene2935	1.02e-67	208.0	COG0080@1|root,COG0080@2|Bacteria,2NP7W@2323|unclassified Bacteria	2|Bacteria	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors	rplK	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0006950,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0010467,GO:0015934,GO:0015968,GO:0016043,GO:0019538,GO:0019843,GO:0022411,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0032984,GO:0032991,GO:0033554,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0042594,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0051716,GO:0065003,GO:0070925,GO:0071496,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02867	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L11,Ribosomal_L11_N
k141_3699_3	933262.AXAM01000079_gene2205	1.86e-115	336.0	COG0081@1|root,COG0081@2|Bacteria,1MUE6@1224|Proteobacteria,42MZP@68525|delta/epsilon subdivisions,2WJ1Z@28221|Deltaproteobacteria,2MHWH@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release	rplA	GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02863	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L1
k141_3699_4	1232437.KL662045_gene2152	2.71e-26	102.0	COG0244@1|root,COG0244@2|Bacteria,1RAN5@1224|Proteobacteria,42R1J@68525|delta/epsilon subdivisions,2WQE8@28221|Deltaproteobacteria,2MKCS@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors	rplJ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02864	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L10
k141_2327_1	1304885.AUEY01000006_gene702	7.55e-109	334.0	COG4670@1|root,COG4670@2|Bacteria,1MUJW@1224|Proteobacteria,42PGU@68525|delta/epsilon subdivisions,2WKKP@28221|Deltaproteobacteria,2MMF3@213118|Desulfobacterales	28221|Deltaproteobacteria	I	Coenzyme A transferase	-	-	2.8.3.1	ko:K01026	ko00620,ko00640,ko00643,ko01100,ko01120,map00620,map00640,map00643,map01100,map01120	-	R00928,R01449,R05508	RC00012,RC00014,RC00137	ko00000,ko00001,ko01000	-	-	-	CoA_trans
k141_2327_2	1232437.KL662039_gene2082	6.74e-34	122.0	COG1406@1|root,COG1406@2|Bacteria,1RFMY@1224|Proteobacteria,42RN1@68525|delta/epsilon subdivisions,2WNY4@28221|Deltaproteobacteria,2MJYZ@213118|Desulfobacterales	28221|Deltaproteobacteria	N	Chemotaxis phosphatase CheX	-	-	-	ko:K03409	ko02030,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheX
k141_3994_1	675813.VIB_001498	8.2e-208	584.0	COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,1RP0W@1236|Gammaproteobacteria,1XTG0@135623|Vibrionales	135623|Vibrionales	H	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor	bioA	-	2.6.1.62	ko:K00833	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03231	RC00006,RC00887	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
k141_1308_4	55601.VANGNB10_cI2134c	3.11e-80	243.0	COG3945@1|root,COG3945@2|Bacteria,1NDGV@1224|Proteobacteria,1SGA3@1236|Gammaproteobacteria,1XWZS@135623|Vibrionales	135623|Vibrionales	S	Hemerythrin HHE cation binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin
k141_1308_7	1517681.HW45_06530	6.55e-151	430.0	COG0648@1|root,COG0648@2|Bacteria,1MX4Y@1224|Proteobacteria,1RQ60@1236|Gammaproteobacteria,1XSWK@135623|Vibrionales	135623|Vibrionales	L	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin	nfo	GO:0003674,GO:0003824,GO:0003906,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008081,GO:0008150,GO:0008152,GO:0008833,GO:0009987,GO:0016787,GO:0016788,GO:0016888,GO:0016893,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360	3.1.21.2	ko:K01151	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AP_endonuc_2
k141_1308_8	1280001.BAOA01000021_gene949	8.72e-68	207.0	COG3445@1|root,COG3445@2|Bacteria,1RDRB@1224|Proteobacteria,1S45G@1236|Gammaproteobacteria,1XX0C@135623|Vibrionales	135623|Vibrionales	S	Acts as a radical domain for damaged PFL and possibly other radical proteins	grcA	GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006566,GO:0006567,GO:0006807,GO:0008150,GO:0008152,GO:0008861,GO:0009056,GO:0009063,GO:0009066,GO:0009068,GO:0009987,GO:0016054,GO:0016407,GO:0016408,GO:0016453,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	-	ko:K06866	-	-	-	-	ko00000	-	-	-	Gly_radical
k141_5258_2	330214.NIDE0992	6.19e-65	210.0	COG1039@1|root,COG1039@2|Bacteria	2|Bacteria	L	RNA-DNA hybrid ribonuclease activity	rnhC	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576	3.1.26.4	ko:K03471	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DUF3378,RNase_HII
k141_5258_5	536227.CcarbDRAFT_3709	3.02e-117	369.0	COG1894@1|root,COG1894@2|Bacteria,1TQB0@1239|Firmicutes,2483E@186801|Clostridia,36EMP@31979|Clostridiaceae	186801|Clostridia	C	Respiratory-chain NADH dehydrogenase domain 51 kDa subunit	-	-	1.12.1.3,1.6.5.3	ko:K00335,ko:K18331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx,Complex1_51K,Fer4,NADH_4Fe-4S,SLBB
k141_5258_7	1121324.CLIT_16c00200	2.61e-79	273.0	COG0840@1|root,COG0840@2|Bacteria,1TP5A@1239|Firmicutes,247S3@186801|Clostridia	186801|Clostridia	NT	methyl-accepting chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal,dCache_1
k141_5258_8	326297.Sama_2880	4.77e-19	99.8	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMV2@1236|Gammaproteobacteria,2Q914@267890|Shewanellaceae	1236|Gammaproteobacteria	T	PFAM histidine kinase, HAMP region domain protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal,dCache_2,sCache_2
k141_5258_9	386415.NT01CX_0993	8.26e-27	99.8	2DN7S@1|root,32UIG@2|Bacteria,1VD9D@1239|Firmicutes,24NPR@186801|Clostridia,36MBJ@31979|Clostridiaceae	186801|Clostridia	K	Helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19,HTH_3
k141_5258_10	1123009.AUID01000005_gene1604	7.44e-85	254.0	COG2406@1|root,COG2406@2|Bacteria,1VD9N@1239|Firmicutes,24Q5S@186801|Clostridia	186801|Clostridia	S	Ferritin-like domain	-	-	1.16.3.1	ko:K03594	ko00860,map00860	-	R00078	RC02758	ko00000,ko00001,ko01000	-	-	-	Ferritin
k141_5258_11	634498.mru_1013	2.39e-62	215.0	COG2081@1|root,arCOG00575@2157|Archaea,2XWX6@28890|Euryarchaeota,23NYK@183925|Methanobacteria	183925|Methanobacteria	S	HI0933-like protein	-	-	-	ko:K07007	-	-	-	-	ko00000	-	-	-	HI0933_like
k141_5258_12	1487921.DP68_09850	4.81e-102	306.0	COG1032@1|root,COG1032@2|Bacteria,1TQF0@1239|Firmicutes,24A0T@186801|Clostridia,36DKI@31979|Clostridiaceae	186801|Clostridia	C	Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
k141_5258_13	1031288.AXAA01000026_gene249	3.78e-44	177.0	28HGC@1|root,2Z7S8@2|Bacteria,1V3ZA@1239|Firmicutes,25DSN@186801|Clostridia,36UEG@31979|Clostridiaceae	186801|Clostridia	S	Bacterial cellulose synthase subunit	-	-	-	-	-	-	-	-	-	-	-	-	BcsB,SPOR
k141_5258_14	1121324.CLIT_14c00880	1.81e-169	488.0	COG1215@1|root,COG1215@2|Bacteria,1TRCI@1239|Firmicutes,25BAQ@186801|Clostridia	186801|Clostridia	M	PFAM Glycosyl transferase family 2	ydaM	-	2.4.1.336	ko:K19003	ko00561,ko01100,map00561,map01100	-	R02689	RC00005,RC00059	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glyco_tranf_2_3,Glycos_transf_2
k141_5258_16	1178540.BA70_12090	2.1e-16	85.1	COG2199@1|root,COG3706@2|Bacteria,1VHAN@1239|Firmicutes,4HQWC@91061|Bacilli,1ZFFR@1386|Bacillus	91061|Bacilli	T	Diguanylate cyclase, GGDEF domain	ydaK	-	-	-	-	-	-	-	-	-	-	-	GGDEF
k141_5258_17	1286171.EAL2_c18120	3.45e-61	193.0	COG3012@1|root,COG3012@2|Bacteria,1V1CC@1239|Firmicutes,24FYC@186801|Clostridia,25WAC@186806|Eubacteriaceae	186801|Clostridia	S	SEC-C motif	secA_2	-	-	-	-	-	-	-	-	-	-	-	SEC-C
k141_5258_18	908338.HMPREF9286_0653	6.12e-12	65.1	2E3QR@1|root,32YNK@2|Bacteria,1VENX@1239|Firmicutes,24QVR@186801|Clostridia,22J14@1570339|Peptoniphilaceae	186801|Clostridia	S	Protein of unknown function (DUF1292)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1292
k141_5258_19	1121324.CLIT_24c01040	0.0	1119.0	COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,247TD@186801|Clostridia,25QH6@186804|Peptostreptococcaceae	186801|Clostridia	O	Belongs to the ClpA ClpB family	clpC	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
k141_5258_20	1286171.EAL2_c01210	1.49e-152	439.0	COG3869@1|root,COG3869@2|Bacteria,1TPBA@1239|Firmicutes,247SS@186801|Clostridia,25WRU@186806|Eubacteriaceae	186801|Clostridia	E	ATP:guanido phosphotransferase, C-terminal catalytic domain	mcsB	-	2.7.14.1	ko:K19405	-	-	R11090	RC00002,RC00203	ko00000,ko01000	-	-	-	ATP-gua_Ptrans
k141_3459_5	1042876.PPS_0331	1.78e-89	270.0	COG0225@1|root,COG0225@2|Bacteria,1MVUS@1224|Proteobacteria,1RNWU@1236|Gammaproteobacteria,1YV0A@136845|Pseudomonas putida group	1236|Gammaproteobacteria	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006807,GO:0006950,GO:0006979,GO:0008113,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016667,GO:0016671,GO:0019538,GO:0030091,GO:0033744,GO:0036456,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0055114,GO:0071704,GO:1901564	1.8.4.11	ko:K07304	-	-	-	-	ko00000,ko01000	-	-	iECSE_1348.ECSE_4525	PMSR
k141_3459_8	326442.PSHAa1115	3.14e-27	107.0	COG2020@1|root,COG2020@2|Bacteria,1MZ7S@1224|Proteobacteria,1S8Y4@1236|Gammaproteobacteria,2Q29R@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	O	Protein of unknown function (DUF1295)	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
k141_3459_9	674977.VMC_18580	4.86e-119	346.0	2BYAF@1|root,2ZWH8@2|Bacteria,1RBZ8@1224|Proteobacteria,1S3VD@1236|Gammaproteobacteria,1Y29R@135623|Vibrionales	135623|Vibrionales	S	Protein of unknown function (DUF3581)	SO4011	-	-	-	-	-	-	-	-	-	-	-	DUF3581
k141_92_1	1219072.VHA01S_030_00530	2.09e-180	515.0	2AAIB@1|root,30ZVG@2|Bacteria,1PMUT@1224|Proteobacteria,1SXC7@1236|Gammaproteobacteria,1Y06U@135623|Vibrionales	135623|Vibrionales	S	CRISPR-associated protein Cse1 (CRISPR_cse1)	-	-	-	ko:K19123	-	-	-	-	ko00000,ko02048	-	-	-	CRISPR_Cse1
k141_92_2	298386.PBPRC0036	1.65e-31	116.0	2DBXF@1|root,2ZBPB@2|Bacteria,1R36G@1224|Proteobacteria,1T63W@1236|Gammaproteobacteria,1XZFM@135623|Vibrionales	135623|Vibrionales	S	CRISPR-associated protein (Cas_Cas5)	-	-	-	ko:K19125	-	-	-	-	ko00000,ko02048	-	-	-	Cas_Cas5d
k141_4460_1	207559.Dde_0900	9.38e-74	224.0	COG1595@1|root,COG1595@2|Bacteria,1R5KY@1224|Proteobacteria,42MEK@68525|delta/epsilon subdivisions,2WMHN@28221|Deltaproteobacteria,2MABF@213115|Desulfovibrionales	2|Bacteria	K	TIGRFAM RNA polymerase	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
k141_4460_2	1121406.JAEX01000022_gene1432	2.49e-11	59.7	29Y17@1|root,30JU5@2|Bacteria,1RFD6@1224|Proteobacteria,42RYM@68525|delta/epsilon subdivisions,2WNKP@28221|Deltaproteobacteria,2MBQ6@213115|Desulfovibrionales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_1759_2	675806.VII_002546	1.68e-21	87.0	2AWQZ@1|root,31NMX@2|Bacteria,1QKCG@1224|Proteobacteria,1TIG0@1236|Gammaproteobacteria,1XZ2D@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_1759_3	675813.VIB_001383	4.01e-164	474.0	COG1058@1|root,COG1058@2|Bacteria,1QUB2@1224|Proteobacteria,1RNXG@1236|Gammaproteobacteria,1XSVF@135623|Vibrionales	135623|Vibrionales	S	Belongs to the CinA family	yfaY	-	-	-	-	-	-	-	-	-	-	-	MoCF_biosynth
k141_1759_4	345073.VC395_1368	1.28e-63	200.0	COG2716@1|root,COG2716@2|Bacteria,1NAIN@1224|Proteobacteria,1SEAU@1236|Gammaproteobacteria,1XTJY@135623|Vibrionales	135623|Vibrionales	E	Glycine cleavage system regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	ACT_6
k141_1759_5	558884.JRGM01000129_gene2965	1.53e-126	388.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMV2@1236|Gammaproteobacteria,1Y596@135624|Aeromonadales	135624|Aeromonadales	T	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal,sCache_2
k141_1759_6	243277.VC_1623	4.3e-234	649.0	COG0019@1|root,COG0019@2|Bacteria,1MW3T@1224|Proteobacteria,1RP8C@1236|Gammaproteobacteria,1XT59@135623|Vibrionales	135623|Vibrionales	H	Belongs to the Orn Lys Arg decarboxylase class-II family. NspC subfamily	nspC	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0019842,GO:0030170,GO:0034641,GO:0036094,GO:0042401,GO:0042710,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0044010,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0044764,GO:0045312,GO:0046204,GO:0046983,GO:0048037,GO:0050662,GO:0051704,GO:0070279,GO:0071704,GO:0097159,GO:0097164,GO:1901363,GO:1901564,GO:1901566,GO:1901576	4.1.1.96	ko:K13747	ko00330,ko01100,map00330,map01100	-	R09081,R09082	RC00299	ko00000,ko00001,ko01000	-	-	-	Orn_DAP_Arg_deC
k141_1759_7	1517681.HW45_07755	4.63e-275	755.0	COG1748@1|root,COG1748@2|Bacteria,1NIU2@1224|Proteobacteria,1RP49@1236|Gammaproteobacteria,1XVG7@135623|Vibrionales	135623|Vibrionales	E	COG1748 Saccharopine dehydrogenase and related proteins	-	-	1.5.1.43	ko:K13746	ko00330,ko01100,map00330,map01100	-	R09079,R09080	RC00053,RC00225	ko00000,ko00001,ko01000	-	-	-	Sacchrp_dh_C,Sacchrp_dh_NADP
k141_1759_8	55601.VANGNB10_cI1166	3.97e-246	706.0	COG0076@1|root,COG0160@1|root,COG0076@2|Bacteria,COG0160@2|Bacteria,1MWUX@1224|Proteobacteria,1RQ8G@1236|Gammaproteobacteria,1XV42@135623|Vibrionales	135623|Vibrionales	E	COG0160 4-aminobutyrate aminotransferase and related aminotransferases	-	-	2.6.1.76,4.1.1.86	ko:K00836,ko:K13745	ko00260,ko01100,ko01120,ko01210,ko01230,map00260,map01100,map01120,map01210,map01230	M00033	R06977,R07650	RC00006,RC00062,RC00299	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3,Pyridoxal_deC
k141_1410_1	177437.HRM2_30670	1.43e-10	62.8	2DBU2@1|root,2ZB3S@2|Bacteria,1N1MT@1224|Proteobacteria,42VJX@68525|delta/epsilon subdivisions,2WSPP@28221|Deltaproteobacteria,2MNKM@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_4
k141_731_2	675815.VOA_002637	1.18e-60	190.0	COG2166@1|root,COG2166@2|Bacteria,1REQB@1224|Proteobacteria,1S44J@1236|Gammaproteobacteria,1Y2NM@135623|Vibrionales	135623|Vibrionales	S	Fe-S metabolism associated domain	-	-	-	ko:K02426	-	-	-	-	ko00000	-	-	-	SufE
k141_731_5	223926.28807363	3.27e-200	565.0	COG0520@1|root,COG0520@2|Bacteria,1MUPD@1224|Proteobacteria,1RNIY@1236|Gammaproteobacteria,1XTR5@135623|Vibrionales	135623|Vibrionales	E	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine	csdA	GO:0003674,GO:0003824,GO:0008483,GO:0016740,GO:0016769	2.8.1.7,4.4.1.16	ko:K01766,ko:K11717	ko00450,ko01100,map00450,map01100	-	R03599,R11528	RC00961,RC01789,RC02313	ko00000,ko00001,ko01000	-	-	-	Aminotran_5
k141_731_6	1280001.BAOA01000081_gene2935	7.18e-110	319.0	COG0693@1|root,COG0693@2|Bacteria,1N7T2@1224|Proteobacteria,1RSBI@1236|Gammaproteobacteria,1XV1A@135623|Vibrionales	135623|Vibrionales	S	monophosphate biosynthesis enzyme	yajL	-	3.5.1.124	ko:K03152	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DJ-1_PfpI
k141_731_7	345073.VC395_2423	9.69e-103	309.0	COG1893@1|root,COG1893@2|Bacteria,1P0AW@1224|Proteobacteria,1RR49@1236|Gammaproteobacteria,1XTJR@135623|Vibrionales	135623|Vibrionales	H	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid	panE	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008677,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605	1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000	-	-	-	ApbA,ApbA_C
k141_731_8	870967.VIS19158_12603	1.04e-65	207.0	COG2802@1|root,COG2802@2|Bacteria,1MYN2@1224|Proteobacteria,1S7UF@1236|Gammaproteobacteria,1XWU4@135623|Vibrionales	135623|Vibrionales	S	to the N-terminal domain of Lon protease	-	-	-	ko:K07157	-	-	-	-	ko00000	-	-	-	LON_substr_bdg
k141_731_9	1280001.BAOA01000081_gene2942	6.3e-238	664.0	COG2211@1|root,COG2211@2|Bacteria,1QTSE@1224|Proteobacteria,1T1FN@1236|Gammaproteobacteria,1XSVM@135623|Vibrionales	135623|Vibrionales	G	COG0477 Permeases of the major facilitator superfamily	ampG	-	-	ko:K08218	ko01501,map01501	M00628	-	-	ko00000,ko00001,ko00002,ko02000	2.A.1.25	-	-	MFS_1
k141_731_10	55601.VANGNB10_cI2085	1.49e-73	226.0	COG0652@1|root,COG0652@2|Bacteria,1R9ZQ@1224|Proteobacteria,1RP9U@1236|Gammaproteobacteria,1XTSG@135623|Vibrionales	135623|Vibrionales	M	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	rotA	-	5.2.1.8	ko:K03767	ko01503,ko04217,map01503,map04217	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04147	-	-	-	Pro_isomerase
k141_731_11	55601.VANGNB10_cI2085	4.06e-71	230.0	COG0652@1|root,COG0652@2|Bacteria,1R9ZQ@1224|Proteobacteria,1RP9U@1236|Gammaproteobacteria,1XTSG@135623|Vibrionales	135623|Vibrionales	M	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	rotA	-	5.2.1.8	ko:K03767	ko01503,ko04217,map01503,map04217	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04147	-	-	-	Pro_isomerase
k141_731_12	1348635.BBJY01000002_gene3487	9e-90	268.0	COG3056@1|root,COG3056@2|Bacteria,1MZ1N@1224|Proteobacteria,1RPG1@1236|Gammaproteobacteria,1XTP6@135623|Vibrionales	135623|Vibrionales	M	lipoprotein	VV2594	-	-	ko:K07286	-	-	-	-	ko00000	-	-	-	Lipoprotein_16
k141_731_13	1219077.VAZ01S_010_00920	2.86e-178	507.0	COG2813@1|root,COG2813@2|Bacteria,1NEMR@1224|Proteobacteria,1RMXE@1236|Gammaproteobacteria,1XU8G@135623|Vibrionales	135623|Vibrionales	J	Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA	rlmG	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0008990,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0052916,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.174	ko:K11391	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	MTS,MTS_N
k141_731_14	983545.Glaag_0520	1.88e-30	111.0	COG0271@1|root,COG0271@2|Bacteria,1MZG5@1224|Proteobacteria,1S91G@1236|Gammaproteobacteria,468Q9@72275|Alteromonadaceae	1236|Gammaproteobacteria	T	BolA-like protein	bolA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008360,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0022603,GO:0022604,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576	-	ko:K05527	-	-	-	-	ko00000,ko03000	-	-	-	BolA
k141_731_15	243277.VC_2295	3.49e-274	756.0	COG1726@1|root,COG1726@2|Bacteria,1MU36@1224|Proteobacteria,1RPU1@1236|Gammaproteobacteria,1XTB1@135623|Vibrionales	135623|Vibrionales	C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol	nqrA	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008137,GO:0008150,GO:0008152,GO:0015672,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030001,GO:0030964,GO:0032991,GO:0044425,GO:0050136,GO:0051179,GO:0051234,GO:0055114,GO:0098796,GO:1902494	1.6.5.8	ko:K00346	-	-	-	-	ko00000,ko01000	-	-	-	NQRA,NQRA_SLBB
k141_731_16	243277.VC_2294	7.3e-264	727.0	COG1805@1|root,COG1805@2|Bacteria,1QTUU@1224|Proteobacteria,1RMGH@1236|Gammaproteobacteria,1XUP5@135623|Vibrionales	135623|Vibrionales	C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol	nqrB	GO:0000166,GO:0003674,GO:0003824,GO:0003954,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008137,GO:0008144,GO:0008150,GO:0008152,GO:0010181,GO:0015672,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0019842,GO:0030001,GO:0030964,GO:0032553,GO:0032991,GO:0036094,GO:0043167,GO:0043168,GO:0044425,GO:0044464,GO:0048037,GO:0050136,GO:0050662,GO:0051179,GO:0051234,GO:0055114,GO:0071944,GO:0097159,GO:0097367,GO:0098796,GO:1901265,GO:1901363,GO:1902444,GO:1902494	1.6.5.8	ko:K00347	-	-	-	-	ko00000,ko01000	-	-	-	NQR2_RnfD_RnfE
k141_731_17	675814.VIC_000691	6.45e-134	385.0	COG2869@1|root,COG2869@2|Bacteria,1MVDI@1224|Proteobacteria,1RR85@1236|Gammaproteobacteria,1XUPV@135623|Vibrionales	135623|Vibrionales	C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol	nqrC	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008150,GO:0008152,GO:0010181,GO:0015672,GO:0016491,GO:0016651,GO:0016655,GO:0030001,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0048037,GO:0050662,GO:0051179,GO:0051234,GO:0055114,GO:0097159,GO:0097367,GO:1901265,GO:1901363	1.6.5.8	ko:K00348	-	-	-	-	ko00000,ko01000	-	-	-	FMN_bind
k141_731_19	1280001.BAOA01000081_gene2951	5.25e-125	357.0	COG2209@1|root,COG2209@2|Bacteria,1R33S@1224|Proteobacteria,1RMWV@1236|Gammaproteobacteria,1XSTK@135623|Vibrionales	135623|Vibrionales	C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol	nqrE	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008137,GO:0008150,GO:0008152,GO:0015672,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030001,GO:0030964,GO:0032991,GO:0044425,GO:0050136,GO:0051179,GO:0051234,GO:0055114,GO:0098796,GO:1902494	1.6.5.8	ko:K00350	-	-	-	-	ko00000,ko01000	-	-	-	Rnf-Nqr
k141_1411_1	935837.JAEK01000006_gene4301	8.48e-52	175.0	COG1052@1|root,COG1052@2|Bacteria,1TPCX@1239|Firmicutes,4HASY@91061|Bacilli,1ZB0I@1386|Bacillus	91061|Bacilli	CH	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family	-	-	1.1.1.215,1.1.1.26,1.1.1.79,1.1.1.81	ko:K00015,ko:K00090	ko00030,ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00030,map00260,map00620,map00630,map01100,map01110,map01120	-	R00465,R00717,R01388,R01392,R01739	RC00031,RC00042,RC00084	ko00000,ko00001,ko01000	-	-	-	2-Hacid_dh,2-Hacid_dh_C
k141_3103_1	491952.Mar181_0192	4.22e-78	242.0	COG3220@1|root,COG3220@2|Bacteria,1MURE@1224|Proteobacteria,1RQ9H@1236|Gammaproteobacteria,1XJ41@135619|Oceanospirillales	135619|Oceanospirillales	S	Protein of unknown function (DUF692)	-	-	-	ko:K09930	-	-	-	-	ko00000	-	-	-	DUF692
k141_3103_2	511062.GU3_00300	1.17e-32	116.0	COG5572@1|root,COG5572@2|Bacteria,1MZ6Q@1224|Proteobacteria,1S9Q2@1236|Gammaproteobacteria,1Y6KN@135624|Aeromonadales	135624|Aeromonadales	S	Predicted integral membrane protein (DUF2282)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2282
k141_3103_3	202955.BBND01000005_gene328	2.52e-12	62.4	COG5660@1|root,COG5660@2|Bacteria,1NH4R@1224|Proteobacteria,1SH4J@1236|Gammaproteobacteria,3NPW6@468|Moraxellaceae	1236|Gammaproteobacteria	S	Transmembrane anti-sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
k141_3103_4	491952.Mar181_0195	1.01e-85	259.0	COG1595@1|root,COG1595@2|Bacteria,1RHKM@1224|Proteobacteria,1S48U@1236|Gammaproteobacteria,1XK4H@135619|Oceanospirillales	135619|Oceanospirillales	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
k141_409_1	1190606.AJYG01000181_gene1850	2.05e-22	90.1	COG4104@1|root,COG4104@2|Bacteria,1N8V2@1224|Proteobacteria,1SHUF@1236|Gammaproteobacteria,1XYP8@135623|Vibrionales	135623|Vibrionales	S	PAAR repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	PAAR_motif
k141_409_2	1238450.VIBNISOn1_340011	5.29e-27	116.0	COG0790@1|root,COG0790@2|Bacteria,1NWNM@1224|Proteobacteria,1SPQV@1236|Gammaproteobacteria,1XWUC@135623|Vibrionales	135623|Vibrionales	S	COG0790 FOG TPR repeat, SEL1 subfamily	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_409_3	1238450.VIBNISOn1_340026	9.76e-80	241.0	COG3516@1|root,COG3516@2|Bacteria,1RBNB@1224|Proteobacteria,1S2BT@1236|Gammaproteobacteria,1XX14@135623|Vibrionales	135623|Vibrionales	S	protein conserved in bacteria	-	-	-	ko:K11901	ko02025,map02025	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	T6SS_VipA
k141_409_4	345073.VC395_A0101	3.24e-310	850.0	COG3517@1|root,COG3517@2|Bacteria,1MU5C@1224|Proteobacteria,1RNP7@1236|Gammaproteobacteria,1XUBM@135623|Vibrionales	135623|Vibrionales	S	protein conserved in bacteria	-	-	-	ko:K11900	ko02025,map02025	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	VipB
k141_409_5	1348635.BBJY01000001_gene2537	1.52e-57	182.0	COG3518@1|root,COG3518@2|Bacteria,1RE8H@1224|Proteobacteria,1S45J@1236|Gammaproteobacteria,1XWXA@135623|Vibrionales	135623|Vibrionales	S	protein conserved in bacteria	-	-	-	ko:K11905	-	M00334	-	-	ko00000,ko00002,ko02044	-	-	-	GPW_gp25
k141_409_6	55601.VANGNB10_cII0073	0.0	891.0	COG3519@1|root,COG3519@2|Bacteria,1MUY4@1224|Proteobacteria,1RPK4@1236|Gammaproteobacteria,1XTN2@135623|Vibrionales	135623|Vibrionales	S	protein conserved in bacteria	vasA	-	-	ko:K11896	-	M00334	-	-	ko00000,ko00002,ko02044	3.A.23.1	-	-	T6SS_TssF
k141_409_7	345073.VC395_A0104	9.35e-147	424.0	COG3520@1|root,COG3520@2|Bacteria,1MWVS@1224|Proteobacteria,1RQD5@1236|Gammaproteobacteria,1XT7D@135623|Vibrionales	135623|Vibrionales	S	protein conserved in bacteria	-	-	-	ko:K11895	ko02025,map02025	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	T6SS_TssG
k141_409_8	870967.VIS19158_07045	2e-121	369.0	COG3456@1|root,COG3456@2|Bacteria,1MUKE@1224|Proteobacteria,1RQGW@1236|Gammaproteobacteria,1XUQ5@135623|Vibrionales	135623|Vibrionales	T	conserved protein, contains FHA domain	-	-	-	ko:K11894	-	-	-	-	ko00000,ko02044	3.A.23.1	-	-	FHA
k141_732_1	1348635.BBJY01000004_gene2999	2.98e-81	253.0	COG0524@1|root,COG0524@2|Bacteria,1MUUC@1224|Proteobacteria,1RMN2@1236|Gammaproteobacteria,1XTRF@135623|Vibrionales	135623|Vibrionales	G	COG0524 Sugar kinases, ribokinase family	-	-	2.7.1.73	ko:K00892	ko00230,map00230	-	R01131,R01228	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
k141_3462_1	96561.Dole_2689	2.04e-14	83.6	COG3103@1|root,COG3103@2|Bacteria,1MVX1@1224|Proteobacteria,42PXB@68525|delta/epsilon subdivisions,2WJKN@28221|Deltaproteobacteria,2MJ1J@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Sh3 type 3 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF1302
k141_3462_2	1321815.HMPREF9193_01698	6.67e-16	77.8	COG2834@1|root,COG2834@2|Bacteria,2J5AT@203691|Spirochaetes	203691|Spirochaetes	M	Outer membrane lipoprotein-sorting protein	-	-	-	-	-	-	-	-	-	-	-	-	LolA_like
k141_2405_2	1202962.KB907153_gene424	2.07e-53	181.0	COG0115@1|root,COG0115@2|Bacteria,1MZAK@1224|Proteobacteria,1RPPG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	EH	4-amino-4-deoxychorismate lyase	pabC	GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008696,GO:0009987,GO:0016829,GO:0016830,GO:0016833,GO:0019752,GO:0019842,GO:0030170,GO:0034641,GO:0036094,GO:0042558,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0044237,GO:0044281,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0070279,GO:0071704,GO:0097159,GO:1901360,GO:1901363,GO:1901564	4.1.3.38	ko:K02619	ko00790,map00790	-	R05553	RC01843,RC02148	ko00000,ko00001,ko01000	-	-	iAPECO1_1312.APECO1_177,iE2348C_1286.E2348C_1188,iECED1_1282.ECED1_1239,iECNA114_1301.ECNA114_1153,iECOK1_1307.ECOK1_1203,iECS88_1305.ECS88_1110,iECSF_1327.ECSF_0995,iECUMN_1333.ECUMN_1273,iJN746.PP_1917,iPC815.YPO1603,iUMN146_1321.UM146_11845,iUTI89_1310.UTI89_C1222,ic_1306.c1366	Aminotran_4
k141_2405_3	674977.VMC_28480	2.75e-121	359.0	COG1559@1|root,COG1559@2|Bacteria,1MUQF@1224|Proteobacteria,1RMWD@1236|Gammaproteobacteria,1XTTP@135623|Vibrionales	135623|Vibrionales	S	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation	mltG	-	-	ko:K07082	-	-	-	-	ko00000	-	-	-	YceG
k141_2405_4	1348635.BBJY01000007_gene99	1.01e-104	307.0	COG0125@1|root,COG0125@2|Bacteria,1MV9C@1224|Proteobacteria,1S26C@1236|Gammaproteobacteria,1XTND@135623|Vibrionales	135623|Vibrionales	F	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	tmk	GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylate_kin
k141_2405_5	675816.VIA_003429	1.15e-92	285.0	COG0470@1|root,COG0470@2|Bacteria,1MY1W@1224|Proteobacteria,1RNYA@1236|Gammaproteobacteria,1XU24@135623|Vibrionales	135623|Vibrionales	L	dna polymerase iii	holB	-	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNApol3-delta_C
k141_2405_6	29495.EA26_16115	3.84e-146	416.0	COG0084@1|root,COG0084@2|Bacteria,1MUC0@1224|Proteobacteria,1RP6E@1236|Gammaproteobacteria,1XTHX@135623|Vibrionales	135623|Vibrionales	L	COG0084 Mg-dependent DNase	ycfH	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
k141_4792_1	55601.VANGNB10_cII0098c	1.99e-07	57.4	COG3110@1|root,COG3110@2|Bacteria,1RK33@1224|Proteobacteria,1RZRX@1236|Gammaproteobacteria,1XWDI@135623|Vibrionales	135623|Vibrionales	S	Belongs to the UPF0319 family	SO3571	-	-	ko:K09909	-	-	-	-	ko00000	-	-	-	DUF2057
k141_4792_3	1056512.D515_02163	6.51e-165	480.0	COG3307@1|root,COG3307@2|Bacteria,1N225@1224|Proteobacteria,1RQWW@1236|Gammaproteobacteria,1XSTD@135623|Vibrionales	135623|Vibrionales	M	COG3307 Lipid A core - O-antigen ligase and related enzymes	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
k141_410_1	1265505.ATUG01000001_gene4124	1.1e-45	166.0	COG1132@1|root,COG1132@2|Bacteria,1MXC2@1224|Proteobacteria,42PQK@68525|delta/epsilon subdivisions,2WJCT@28221|Deltaproteobacteria,2MN7I@213118|Desulfobacterales	28221|Deltaproteobacteria	V	ABC transporter transmembrane region	-	-	-	ko:K06147,ko:K06148	-	-	-	-	ko00000,ko02000	3.A.1,3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
k141_2406_1	933262.AXAM01000073_gene3360	6.05e-52	171.0	COG0159@1|root,COG0159@2|Bacteria,1MXJV@1224|Proteobacteria,42N5B@68525|delta/epsilon subdivisions,2WJX4@28221|Deltaproteobacteria,2MIHZ@213118|Desulfobacterales	28221|Deltaproteobacteria	E	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate	trpA	-	4.2.1.20	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_syntA
k141_2406_2	177437.HRM2_22980	6.41e-14	67.0	2EACD@1|root,334GB@2|Bacteria,1NETT@1224|Proteobacteria,42V8Z@68525|delta/epsilon subdivisions,2WRR6@28221|Deltaproteobacteria,2MKWJ@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	3.6.1.1	ko:K01507	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	-
k141_411_1	1121396.KB893077_gene731	5.6e-28	103.0	COG1359@1|root,COG1359@2|Bacteria,1NGPW@1224|Proteobacteria,42TXG@68525|delta/epsilon subdivisions,2WQI4@28221|Deltaproteobacteria,2MKN6@213118|Desulfobacterales	28221|Deltaproteobacteria	S	PFAM Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	ABM
k141_411_2	1121396.KB893118_gene3101	4.81e-83	258.0	COG1032@1|root,COG1032@2|Bacteria,1MY2Y@1224|Proteobacteria,42NG3@68525|delta/epsilon subdivisions,2WJ95@28221|Deltaproteobacteria,2MJ57@213118|Desulfobacterales	28221|Deltaproteobacteria	C	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,DUF4070,Radical_SAM
k141_2061_2	1348635.BBJY01000017_gene4113	4.83e-101	295.0	COG2917@1|root,COG2917@2|Bacteria,1NWIZ@1224|Proteobacteria,1RQAB@1236|Gammaproteobacteria,1XT4H@135623|Vibrionales	135623|Vibrionales	D	probably involved in intracellular septation	ispZ	-	-	ko:K06190	-	-	-	-	ko00000	-	-	-	IspA
k141_2061_5	223926.28806965	4.87e-45	150.0	2B0AA@1|root,31SMA@2|Bacteria,1QJXS@1224|Proteobacteria,1THZX@1236|Gammaproteobacteria,1XY1G@135623|Vibrionales	135623|Vibrionales	S	Type II secretion system (T2SS) pilotin, S protein	-	-	-	-	-	-	-	-	-	-	-	-	T2SSS_2
k141_2061_7	314282.PCNPT3_12035	1.35e-36	157.0	COG0612@1|root,COG0612@2|Bacteria,1NAH6@1224|Proteobacteria,1RNKC@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Peptidase, M16	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
k141_4473_6	55601.VANGNB10_cI1837c	7.65e-184	518.0	COG0416@1|root,COG0416@2|Bacteria,1MVM3@1224|Proteobacteria,1RM7R@1236|Gammaproteobacteria,1XU27@135623|Vibrionales	135623|Vibrionales	I	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA	plsX	GO:0003674,GO:0003824,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0044238,GO:0071704,GO:1901576	2.3.1.15	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FA_synthesis
k141_4473_7	29495.EA26_16170	2.64e-31	109.0	COG0333@1|root,COG0333@2|Bacteria,1N6RF@1224|Proteobacteria,1SC9G@1236|Gammaproteobacteria,1XYWA@135623|Vibrionales	135623|Vibrionales	J	Belongs to the bacterial ribosomal protein bL32 family	rpmF	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02911	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_L32p
k141_4473_8	243277.VC_2026	4.94e-100	292.0	COG1399@1|root,COG1399@2|Bacteria,1PGKW@1224|Proteobacteria,1RRK3@1236|Gammaproteobacteria,1XTCK@135623|Vibrionales	135623|Vibrionales	S	metal-binding, possibly nucleic acid-binding protein	yceD	-	-	ko:K07040	-	-	-	-	ko00000	-	-	-	DUF177
k141_4473_9	796620.VIBC2010_18314	2.51e-80	244.0	COG0424@1|root,COG0424@2|Bacteria,1RDA9@1224|Proteobacteria,1S3TQ@1236|Gammaproteobacteria,1XUK8@135623|Vibrionales	135623|Vibrionales	D	COG0424 Nucleotide-binding protein implicated in inhibition of septum formation	yceF	-	-	-	-	-	-	-	-	-	-	-	Maf
k141_4473_10	55601.VANGNB10_cI1841c	2.26e-184	518.0	COG0564@1|root,COG0564@2|Bacteria,1MVDX@1224|Proteobacteria,1RPAN@1236|Gammaproteobacteria,1XT4V@135623|Vibrionales	135623|Vibrionales	J	Responsible for synthesis of pseudouridine from uracil	rluC	GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	5.4.99.24	ko:K06179	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
k141_4473_11	675813.VIB_001622	0.0	981.0	COG1530@1|root,COG1530@2|Bacteria,1MV65@1224|Proteobacteria,1RMDS@1236|Gammaproteobacteria,1XTUQ@135623|Vibrionales	135623|Vibrionales	J	Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs	rne	-	3.1.26.12	ko:K08300	ko03018,map03018	M00394	-	-	ko00000,ko00001,ko00002,ko01000,ko03009,ko03019	-	-	-	RNase_E_G,S1
k141_4473_13	484770.UFO1_1337	8.57e-30	112.0	COG2221@1|root,COG2221@2|Bacteria,1VBGQ@1239|Firmicutes,4H8VA@909932|Negativicutes	909932|Negativicutes	C	TIGRFAM C_GCAxxG_C_C family protein	-	-	-	-	-	-	-	-	-	-	-	-	C_GCAxxG_C_C
k141_4473_14	223926.28807114	0.0	1545.0	COG1012@1|root,COG1454@1|root,COG1012@2|Bacteria,COG1454@2|Bacteria,1MVPH@1224|Proteobacteria,1RNBH@1236|Gammaproteobacteria,1XTSP@135623|Vibrionales	135623|Vibrionales	C	belongs to the iron- containing alcohol dehydrogenase family	adhE	-	1.1.1.1,1.2.1.10	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	-	R00228,R00623,R00754,R01172,R04880,R05233,R05234,R06917,R06927	RC00004,RC00050,RC00088,RC00099,RC00116,RC00184,RC00649,RC01195	ko00000,ko00001,ko01000	-	-	-	Aldedh,Fe-ADH
k141_4473_15	675815.VOA_002378	1.61e-119	345.0	COG2095@1|root,COG2095@2|Bacteria,1MX5T@1224|Proteobacteria,1RPZ3@1236|Gammaproteobacteria,1XU2X@135623|Vibrionales	135623|Vibrionales	U	UPF0056 membrane protein	-	-	-	ko:K05595	-	-	-	-	ko00000,ko02000	2.A.95.1	-	-	MarC
k141_4473_16	1219065.VPR01S_03_02240	6.65e-138	397.0	COG2126@1|root,COG2126@2|Bacteria,1MXCS@1224|Proteobacteria,1RPCN@1236|Gammaproteobacteria,1XTRC@135623|Vibrionales	135623|Vibrionales	J	COG1226 Kef-type K transport systems	-	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans
k141_4473_17	1348635.BBJY01000007_gene120	2.8e-238	658.0	COG0136@1|root,COG0136@2|Bacteria,1MUHG@1224|Proteobacteria,1RMN3@1236|Gammaproteobacteria,1XTI7@135623|Vibrionales	135623|Vibrionales	E	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate	asd1	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004073,GO:0006082,GO:0006520,GO:0006549,GO:0006553,GO:0006555,GO:0006566,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009081,GO:0009082,GO:0009085,GO:0009086,GO:0009088,GO:0009089,GO:0009097,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
k141_4473_18	55601.VANGNB10_cI1848c	9.6e-56	196.0	COG2198@1|root,COG2198@2|Bacteria,1QJH8@1224|Proteobacteria,1THH1@1236|Gammaproteobacteria,1XVSX@135623|Vibrionales	135623|Vibrionales	T	Signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Hpt
k141_4473_19	55601.VANGNB10_cI1849c	8.42e-175	494.0	COG3081@1|root,COG3081@2|Bacteria,1NXJU@1224|Proteobacteria,1RP8N@1236|Gammaproteobacteria,1XU12@135623|Vibrionales	135623|Vibrionales	S	Nucleoid-associated protein	yejK	-	-	ko:K06899	-	-	-	-	ko00000,ko03036	-	-	-	NA37
k141_4473_21	675806.VII_001786	0.0	878.0	COG3083@1|root,COG3083@2|Bacteria,1MX6X@1224|Proteobacteria,1RPAU@1236|Gammaproteobacteria,1XVE8@135623|Vibrionales	135623|Vibrionales	S	hydrolase of alkaline phosphatase superfamily	-	-	-	ko:K07014	-	-	-	-	ko00000	-	-	-	DUF3413,Sulfatase
k141_1054_1	1121289.JHVL01000001_gene1881	1.05e-251	808.0	COG3391@1|root,COG4733@1|root,COG3391@2|Bacteria,COG4733@2|Bacteria,1TT7S@1239|Firmicutes,24EIJ@186801|Clostridia,36GQ1@31979|Clostridiaceae	186801|Clostridia	S	ig-like, plexins, transcription factors	-	-	-	-	-	-	-	-	-	-	-	-	TIG,fn3
k141_1054_2	1209989.TepiRe1_2683	1.59e-28	133.0	28IXE@1|root,2Z8VB@2|Bacteria,1U464@1239|Firmicutes,24BH6@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_1054_5	1508644.SFBmNL_01536	3.84e-190	553.0	COG5293@1|root,COG5293@2|Bacteria,1V11B@1239|Firmicutes,24FB1@186801|Clostridia	186801|Clostridia	S	Uncharacterised protein conserved in bacteria (DUF2326)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2326
k141_1054_6	1508644.SFBmNL_00137	1.4e-26	99.8	2EGFA@1|root,33A7A@2|Bacteria,1VQNH@1239|Firmicutes,24V7U@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_1054_7	1508644.SFBmNL_00136	4.32e-115	341.0	COG5635@1|root,COG5635@2|Bacteria,1VPBQ@1239|Firmicutes,24VAQ@186801|Clostridia	186801|Clostridia	T	Nacht domain	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_1054_8	273068.TTE0668	3.39e-232	664.0	COG1086@1|root,COG1086@2|Bacteria,1TR3W@1239|Firmicutes,247PW@186801|Clostridia,42EJW@68295|Thermoanaerobacterales	186801|Clostridia	GM	PFAM Polysaccharide biosynthesis protein	capD	-	-	-	-	-	-	-	-	-	-	-	CoA_binding_3,Polysacc_synt_2
k141_1054_10	1345695.CLSA_c39400	2.16e-24	115.0	COG0699@1|root,COG0699@2|Bacteria,1U979@1239|Firmicutes,24UQD@186801|Clostridia	186801|Clostridia	S	Dynamin family	-	-	-	-	-	-	-	-	-	-	-	-	Dynamin_N
k141_3193_7	426716.JOAJ01000002_gene2204	3.76e-37	143.0	COG4695@1|root,COG4695@2|Bacteria	2|Bacteria	N	Portal protein	-	-	-	-	-	-	-	-	-	-	-	-	Phage_Mu_F,Phage_min_cap2,Phage_portal
k141_4188_4	1026882.MAMP_01584	0.000476	46.6	COG4970@1|root,COG4970@2|Bacteria,1N7RS@1224|Proteobacteria,1SCFB@1236|Gammaproteobacteria,4618A@72273|Thiotrichales	72273|Thiotrichales	NU	Type II transport protein GspH	-	-	-	ko:K08084	-	-	-	-	ko00000,ko02044	3.A.15.2	-	-	GspH,N_methyl
k141_4188_5	335543.Sfum_1839	1.23e-33	125.0	COG1752@1|root,COG1752@2|Bacteria,1MUM9@1224|Proteobacteria,42R8Z@68525|delta/epsilon subdivisions,2WMXX@28221|Deltaproteobacteria,2MQMD@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Patatin-like phospholipase	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin,cNMP_binding
k141_206_2	525897.Dbac_0843	4.03e-154	449.0	COG0535@1|root,COG1433@1|root,COG0535@2|Bacteria,COG1433@2|Bacteria,1MWDC@1224|Proteobacteria,42MHB@68525|delta/epsilon subdivisions,2WIPH@28221|Deltaproteobacteria,2M837@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	SMART Elongator protein 3 MiaB NifB	nifB	-	-	ko:K02585	-	-	-	-	ko00000	-	-	-	Nitro_FeMo-Co,Radical_SAM
k141_3863_1	283699.D172_3622	7.68e-46	182.0	COG0642@1|root,COG0642@2|Bacteria,1NXDJ@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,Response_reg
k141_3863_2	349521.HCH_00277	1.63e-52	177.0	COG0834@1|root,COG0834@2|Bacteria,1MZJY@1224|Proteobacteria,1SCZG@1236|Gammaproteobacteria,1XQE9@135619|Oceanospirillales	135619|Oceanospirillales	ET	ABC-type amino acid transport signal transduction systems, periplasmic component domain	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	-
k141_3863_3	279714.FuraDRAFT_2177	3.8e-119	355.0	COG1752@1|root,COG1752@2|Bacteria,1R5GI@1224|Proteobacteria,2VPCG@28216|Betaproteobacteria,2KQ13@206351|Neisseriales	206351|Neisseriales	S	Patatin-like phospholipase	-	-	-	-	-	-	-	-	-	-	-	-	Patatin
k141_3863_4	768704.Desmer_1087	4.93e-47	164.0	COG3279@1|root,COG3279@2|Bacteria,1V14X@1239|Firmicutes,24BG9@186801|Clostridia,25ZYI@186807|Peptococcaceae	186801|Clostridia	K	PFAM response regulator receiver	-	-	-	ko:K02477,ko:K07705	ko02020,map02020	M00492	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	LytTR,Response_reg
k141_3863_5	207559.Dde_0160	9.47e-181	528.0	COG3275@1|root,COG3275@2|Bacteria,1QUB1@1224|Proteobacteria,42PAD@68525|delta/epsilon subdivisions,2WKGB@28221|Deltaproteobacteria,2M9HF@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	histidine kinase internal region	lytS	-	2.7.13.3	ko:K02478,ko:K07704	ko02020,map02020	M00492	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	5TM-5TMR_LYT,GAF_2,GAF_3,HATPase_c,His_kinase,SpoVT_C
k141_229_1	879212.DespoDRAFT_00876	1.29e-101	317.0	COG0058@1|root,COG0058@2|Bacteria,1MW4J@1224|Proteobacteria,42N22@68525|delta/epsilon subdivisions,2WIMH@28221|Deltaproteobacteria,2MJ9A@213118|Desulfobacterales	28221|Deltaproteobacteria	G	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties	-	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	Phosphorylase
k141_1876_1	1504823.CCMM01000008_gene818	2.7e-58	195.0	COG4974@1|root,COG4974@2|Bacteria,2NNN8@2323|unclassified Bacteria	2|Bacteria	L	Phage integrase, N-terminal SAM-like domain	xerD	-	-	ko:K03733,ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_int_SAM_4,Phage_integrase
k141_4206_1	1128912.GMES_1126	2.81e-18	87.0	COG3203@1|root,COG3203@2|Bacteria,1R91C@1224|Proteobacteria,1RTSN@1236|Gammaproteobacteria,467KV@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_3881_1	96561.Dole_0578	1.62e-69	211.0	COG1433@1|root,COG1433@2|Bacteria,1RDPR@1224|Proteobacteria,42SR6@68525|delta/epsilon subdivisions,2WPP8@28221|Deltaproteobacteria,2MJXD@213118|Desulfobacterales	28221|Deltaproteobacteria	S	PFAM Dinitrogenase iron-molybdenum cofactor	-	-	-	-	-	-	-	-	-	-	-	-	Nitro_FeMo-Co
k141_3881_2	1265505.ATUG01000001_gene3954	1.3e-53	171.0	COG1433@1|root,COG1433@2|Bacteria,1MZ77@1224|Proteobacteria,42U3G@68525|delta/epsilon subdivisions,2WQ5N@28221|Deltaproteobacteria,2MKGB@213118|Desulfobacterales	28221|Deltaproteobacteria	S	PFAM Dinitrogenase iron-molybdenum cofactor	-	-	-	-	-	-	-	-	-	-	-	-	Nitro_FeMo-Co
k141_1486_1	1121324.CLIT_16c00130	0.0	1066.0	COG1615@1|root,COG1615@2|Bacteria,1TQHM@1239|Firmicutes,248PM@186801|Clostridia,25SRS@186804|Peptostreptococcaceae	186801|Clostridia	S	Uncharacterised protein family (UPF0182)	-	-	-	ko:K09118	-	-	-	-	ko00000	-	-	-	UPF0182
k141_1486_5	1292035.H476_0804	1.16e-202	583.0	COG0747@1|root,COG0747@2|Bacteria,1TQ0N@1239|Firmicutes,25CDM@186801|Clostridia,25SEU@186804|Peptostreptococcaceae	186801|Clostridia	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
k141_1486_6	350688.Clos_1342	1.12e-36	140.0	COG0601@1|root,COG0601@2|Bacteria,1TP1S@1239|Firmicutes,247IP@186801|Clostridia,36F10@31979|Clostridiaceae	186801|Clostridia	P	PFAM binding-protein-dependent transport systems inner membrane component	appB	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
k141_1486_7	1408254.T458_18700	5.03e-43	156.0	COG1173@1|root,COG1173@2|Bacteria,1TP4R@1239|Firmicutes,4HBB9@91061|Bacilli,274TA@186822|Paenibacillaceae	91061|Bacilli	EP	Peptide ABC transporter permease	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1,OppC_N
k141_1486_9	1121324.CLIT_16c00140	7.17e-88	270.0	COG0668@1|root,COG0668@2|Bacteria,1TR9Z@1239|Firmicutes,25M4G@186801|Clostridia,25RIT@186804|Peptostreptococcaceae	186801|Clostridia	M	Mechanosensitive ion channel	-	-	-	ko:K03442	-	-	-	-	ko00000,ko02000	1.A.23.2	-	-	MS_channel,TM_helix
k141_1486_13	1121324.CLIT_10c01080	1.23e-27	102.0	2E5UQ@1|root,330IY@2|Bacteria,1VI50@1239|Firmicutes,24QVH@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_2821_1	1121447.JONL01000009_gene2555	1.08e-131	473.0	COG2931@1|root,COG3210@1|root,COG4625@1|root,COG2931@2|Bacteria,COG3210@2|Bacteria,COG4625@2|Bacteria,1MU7T@1224|Proteobacteria	1224|Proteobacteria	Q	COG2931, RTX toxins and related Ca2 -binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	HCBP_related,HemolysinCabind
k141_1877_1	1121413.JMKT01000016_gene28	2.27e-11	69.7	28IY7@1|root,2Z8VZ@2|Bacteria,1R984@1224|Proteobacteria,42TT4@68525|delta/epsilon subdivisions,2WTTP@28221|Deltaproteobacteria,2MBE0@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4857)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4857
k141_1211_1	298386.PBPRA1988	0.0	1286.0	COG0479@1|root,COG0674@1|root,COG1013@1|root,COG1014@1|root,COG0479@2|Bacteria,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,1MVM0@1224|Proteobacteria,1RNNX@1236|Gammaproteobacteria,1XVUA@135623|Vibrionales	135623|Vibrionales	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	nifJ	-	1.2.7.1	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00173,M00307	R01196,R10866	RC00004,RC02742	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	EKR,Fer4,Fer4_16,Fer4_6,PFOR_II,POR,POR_N,TPP_enzyme_C
k141_1211_2	298386.PBPRA1989	4.75e-281	781.0	COG0493@1|root,COG2221@1|root,COG0493@2|Bacteria,COG2221@2|Bacteria,1MU2H@1224|Proteobacteria,1RREP@1236|Gammaproteobacteria,1XUH7@135623|Vibrionales	135623|Vibrionales	C	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_20,Pyr_redox_2
k141_1211_3	1515746.HR45_04805	2.74e-62	200.0	COG1309@1|root,COG1309@2|Bacteria,1N1X6@1224|Proteobacteria,1S9GI@1236|Gammaproteobacteria,2QBYI@267890|Shewanellaceae	1236|Gammaproteobacteria	K	PFAM regulatory protein TetR	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_9,TetR_N
k141_230_2	887062.HGR_05556	4.26e-67	211.0	COG0625@1|root,COG0625@2|Bacteria,1MY47@1224|Proteobacteria,2VI89@28216|Betaproteobacteria,4AB74@80864|Comamonadaceae	28216|Betaproteobacteria	O	Glutathione S-transferase	gst	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C,GST_C_3,GST_N,GST_N_2,GST_N_3
k141_1489_1	439235.Dalk_3869	3.67e-114	335.0	COG1250@1|root,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,42M6J@68525|delta/epsilon subdivisions,2WJZQ@28221|Deltaproteobacteria,2MJ78@213118|Desulfobacterales	28221|Deltaproteobacteria	I	PFAM 3-hydroxyacyl-CoA dehydrogenase	mmgB	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
k141_3882_2	522772.Dacet_1616	5.05e-35	137.0	COG2207@1|root,COG2207@2|Bacteria	2|Bacteria	K	Transcriptional regulator	ybtA	-	-	ko:K05372	-	-	-	-	ko00000,ko03000	-	-	-	HTH_18
k141_3882_3	1121396.KB892990_gene4508	2.44e-37	134.0	COG2834@1|root,COG2834@2|Bacteria,1MXW0@1224|Proteobacteria,42QPE@68525|delta/epsilon subdivisions,2WN39@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Outer membrane lipoprotein-sorting protein	-	-	-	-	-	-	-	-	-	-	-	-	LolA_like
k141_1879_1	1238450.VIBNISOn1_720003	4.41e-87	258.0	COG0454@1|root,COG0454@2|Bacteria,1QUS5@1224|Proteobacteria,1RRHY@1236|Gammaproteobacteria,1XVWU@135623|Vibrionales	135623|Vibrionales	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_10
k141_1879_3	1051646.VITU9109_16618	2.12e-58	181.0	COG3668@1|root,COG3668@2|Bacteria,1N75M@1224|Proteobacteria,1S67C@1236|Gammaproteobacteria,1XY7M@135623|Vibrionales	135623|Vibrionales	S	Belongs to the RelE toxin family	-	-	-	ko:K19092	-	-	-	-	ko00000,ko02048	-	-	-	ParE_toxin
k141_2177_1	575788.VS_II0932	1.88e-286	794.0	COG1123@1|root,COG4172@2|Bacteria,1MU09@1224|Proteobacteria,1RMEI@1236|Gammaproteobacteria,1XSCK@135623|Vibrionales	135623|Vibrionales	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K02031,ko:K02032,ko:K13896	ko02010,ko02024,map02010,map02024	M00239,M00349	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.21,3.A.1.5.24	-	-	ABC_tran,oligo_HPY
k141_2177_3	1111728.ATYS01000010_gene278	9.6e-26	107.0	COG3048@1|root,COG3048@2|Bacteria,1MUJS@1224|Proteobacteria,1RNBW@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Belongs to the serine threonine dehydratase family. DsdA subfamily	dsdA	GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008721,GO:0009987,GO:0016829,GO:0016840,GO:0016841,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0071704,GO:1901564	4.3.1.18	ko:K01753	ko00260,map00260	-	R00221	RC02600	ko00000,ko00001,ko01000	-	-	-	PALP
k141_2177_4	1248232.BANQ01000029_gene3944	7.36e-43	145.0	COG2501@1|root,COG2501@2|Bacteria,1N8C4@1224|Proteobacteria,1SCIR@1236|Gammaproteobacteria,1XY0I@135623|Vibrionales	135623|Vibrionales	S	S4 domain	-	-	-	ko:K14761	-	-	-	-	ko00000,ko03009	-	-	-	S4_2
k141_3207_2	933262.AXAM01000007_gene2046	8.77e-186	532.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WJKZ@28221|Deltaproteobacteria,2MI48@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Bacterial regulatory protein, Fis family	-	-	-	ko:K07713	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
k141_3207_3	243231.GSU2524	2.23e-32	129.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WKFA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
k141_3542_2	1051646.VITU9109_03745	8.48e-210	584.0	COG4239@1|root,COG4239@2|Bacteria,1MUM5@1224|Proteobacteria,1RNUH@1236|Gammaproteobacteria,1XT25@135623|Vibrionales	135623|Vibrionales	P	transport system permease component	-	-	-	ko:K13895	ko02010,map02010	M00349	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.21,3.A.1.5.24	-	-	BPD_transp_1,OppC_N
k141_3542_3	575788.VS_II0932	1.17e-285	792.0	COG1123@1|root,COG4172@2|Bacteria,1MU09@1224|Proteobacteria,1RMEI@1236|Gammaproteobacteria,1XSCK@135623|Vibrionales	135623|Vibrionales	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K02031,ko:K02032,ko:K13896	ko02010,ko02024,map02010,map02024	M00239,M00349	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.21,3.A.1.5.24	-	-	ABC_tran,oligo_HPY
k141_3542_4	1348635.BBJY01000006_gene472	3.27e-40	139.0	COG2501@1|root,COG2501@2|Bacteria,1N8C4@1224|Proteobacteria,1SCIR@1236|Gammaproteobacteria,1XY0I@135623|Vibrionales	135623|Vibrionales	S	S4 domain	-	-	-	ko:K14761	-	-	-	-	ko00000,ko03009	-	-	-	S4_2
k141_3542_5	1283284.AZUK01000001_gene1626	6.59e-205	575.0	COG1454@1|root,COG1454@2|Bacteria,1MVPH@1224|Proteobacteria,1RREW@1236|Gammaproteobacteria,1Y5SN@135624|Aeromonadales	135624|Aeromonadales	C	Iron-containing alcohol dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Fe-ADH
k141_3542_6	76114.ebA163	6.21e-145	456.0	COG2202@1|root,COG5001@1|root,COG2202@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,2KVXB@206389|Rhodocyclales	206389|Rhodocyclales	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_4
k141_3542_8	55601.VANGNB10_cI2445	8.22e-278	768.0	COG1027@1|root,COG1027@2|Bacteria,1R9JY@1224|Proteobacteria,1RP5Z@1236|Gammaproteobacteria,1XSMK@135623|Vibrionales	135623|Vibrionales	E	Aspartate ammonia-lyase	aspA	-	4.3.1.1	ko:K01744	ko00250,ko01100,map00250,map01100	-	R00490	RC00316,RC02799	ko00000,ko00001,ko01000	-	-	-	FumaraseC_C,Lyase_1
k141_231_1	742727.HMPREF9447_01050	8.23e-95	283.0	COG0110@1|root,COG0110@2|Bacteria,4NHX5@976|Bacteroidetes,2FQ64@200643|Bacteroidia,4AKSW@815|Bacteroidaceae	976|Bacteroidetes	S	Bacterial transferase hexapeptide repeat protein	vat_2	-	-	ko:K18234	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	Hexapep
k141_3543_1	177437.HRM2_42420	1.03e-89	273.0	COG0329@1|root,COG0329@2|Bacteria,1MUCM@1224|Proteobacteria,42M0X@68525|delta/epsilon subdivisions,2WK4D@28221|Deltaproteobacteria,2MHXX@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
k141_1880_1	7739.XP_002594097.1	4.85e-22	99.4	COG1028@1|root,KOG1205@2759|Eukaryota,39IQV@33154|Opisthokonta,3BJRF@33208|Metazoa,3CX6K@33213|Bilateria,487AB@7711|Chordata	33208|Metazoa	Q	oxidoreductase activity	HSD11B1L	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0008150,GO:0008152,GO:0016229,GO:0016491,GO:0031974,GO:0031981,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044464,GO:0055114,GO:0070013	1.1.1.146	ko:K15680	ko00140,ko00980,ko01100,ko05204,map00140,map00980,map01100,map05204	M00109	R02836,R03848,R04758,R04840,R09420	RC00154,RC01491	ko00000,ko00001,ko00002,ko01000	-	-	-	adh_short
k141_1880_2	879212.DespoDRAFT_02108	8.63e-84	257.0	292MF@1|root,2ZQ5C@2|Bacteria,1RCYR@1224|Proteobacteria,42RFG@68525|delta/epsilon subdivisions,2WPKN@28221|Deltaproteobacteria,2MK0P@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF3047)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3047
k141_1880_3	1304888.ATWF01000001_gene1366	4.57e-35	128.0	COG1215@1|root,COG1215@2|Bacteria,2GFVK@200930|Deferribacteres	200930|Deferribacteres	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
k141_2179_1	269797.Mbar_A1641	1.17e-129	382.0	COG0019@1|root,arCOG02268@2157|Archaea,2XSY8@28890|Euryarchaeota,2N93Z@224756|Methanomicrobia	224756|Methanomicrobia	E	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine	lysA	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
k141_2482_1	307480.IW16_21040	1.51e-90	286.0	COG0178@1|root,COG0178@2|Bacteria,4NJCU@976|Bacteroidetes,1HZ64@117743|Flavobacteriia,3ZNRV@59732|Chryseobacterium	976|Bacteroidetes	L	ATPases associated with a variety of cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
k141_2482_2	1095769.CAHF01000022_gene128	2.55e-85	258.0	COG1280@1|root,COG1280@2|Bacteria,1MWA1@1224|Proteobacteria,2VPEY@28216|Betaproteobacteria,474NJ@75682|Oxalobacteraceae	28216|Betaproteobacteria	E	LysE type translocator	leuE_1	-	-	-	-	-	-	-	-	-	-	-	LysE
k141_3208_1	1191299.AJYX01000097_gene1573	1.87e-160	460.0	COG1167@1|root,COG1167@2|Bacteria,1MV6F@1224|Proteobacteria,1RNDN@1236|Gammaproteobacteria,1Y2KC@135623|Vibrionales	135623|Vibrionales	EK	Alanine-glyoxylate amino-transferase	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
k141_1883_1	1224318.DT73_08510	1.84e-114	342.0	COG0246@1|root,COG0246@2|Bacteria,1MVZ7@1224|Proteobacteria,1RNIZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	Belongs to the mannitol dehydrogenase family	dalD	-	1.1.1.11,1.1.1.57	ko:K00007,ko:K00040	ko00040,ko00051,ko01100,map00040,map00051,map01100	M00061	R00868,R02454,R05604	RC00085,RC00102	ko00000,ko00001,ko00002,ko01000	-	-	-	Mannitol_dh,Mannitol_dh_C
k141_232_1	1265505.ATUG01000001_gene2995	2.29e-177	506.0	COG1004@1|root,COG1004@2|Bacteria,1MW5U@1224|Proteobacteria,42MDV@68525|delta/epsilon subdivisions,2WJ3T@28221|Deltaproteobacteria,2MHMX@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	ugd	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
k141_232_2	1232437.KL661986_gene3623	3.64e-179	506.0	COG0451@1|root,COG0451@2|Bacteria,1MU7J@1224|Proteobacteria,42MWH@68525|delta/epsilon subdivisions,2WJMZ@28221|Deltaproteobacteria,2MI1B@213118|Desulfobacterales	28221|Deltaproteobacteria	M	PFAM NAD dependent epimerase dehydratase family	uge	-	5.1.3.6	ko:K08679	ko00520,ko01100,map00520,map01100	-	R01385	RC00289	ko00000,ko00001,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
k141_232_3	1565129.JSFF01000004_gene3194	5.94e-18	82.0	COG1212@1|root,COG1212@2|Bacteria,1MUUU@1224|Proteobacteria,1RMAE@1236|Gammaproteobacteria,2Q9N9@267890|Shewanellaceae	1236|Gammaproteobacteria	M	Activates KDO8N (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in the Shewanella genus	kdsB	-	2.7.7.38	ko:K00979	ko00540,ko01100,map00540,map01100	M00063	R03351,R11396	RC00152,RC00910	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_3
k141_4913_1	1501230.ET33_11590	6.25e-49	171.0	COG3711@1|root,COG3711@2|Bacteria,1TQJJ@1239|Firmicutes,4HBB3@91061|Bacilli,26SX5@186822|Paenibacillaceae	91061|Bacilli	K	antiterminator	glcT	-	-	ko:K03480	-	-	-	-	ko00000,ko03000	-	-	-	CAT_RBD,PRD
k141_4913_2	994573.T472_0208165	4e-300	839.0	COG1263@1|root,COG2190@1|root,COG1263@2|Bacteria,COG2190@2|Bacteria,1TPJ8@1239|Firmicutes,24809@186801|Clostridia,36DWW@31979|Clostridiaceae	186801|Clostridia	G	Pts system	-	-	2.7.1.199	ko:K20116,ko:K20117,ko:K20118	ko00010,ko00520,ko02060,map00010,map00520,map02060	M00809	R02738	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.1.1.13,4.A.1.1.14,4.A.1.1.9	-	-	PTS_EIIA_1,PTS_EIIB,PTS_EIIC
k141_4913_3	1286171.EAL2_c06990	3.57e-116	344.0	COG0111@1|root,COG0111@2|Bacteria,1TSDK@1239|Firmicutes,247Q4@186801|Clostridia,25X37@186806|Eubacteriaceae	186801|Clostridia	EH	D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	2-Hacid_dh,2-Hacid_dh_C
k141_4913_4	1121324.CLIT_5c00430	1.21e-193	567.0	COG0366@1|root,COG0366@2|Bacteria,1TNZ0@1239|Firmicutes,247YM@186801|Clostridia,25QER@186804|Peptostreptococcaceae	186801|Clostridia	G	Alpha-amylase domain	apu	-	2.4.1.25	ko:K00705	ko00500,ko01100,map00500,map01100	-	R05196	RC00049	ko00000,ko00001,ko01000	-	GH77	-	Alpha-amylase,Glyco_hydro_77,Malt_amylase_C
k141_4913_5	1304284.L21TH_1975	9.4e-211	605.0	COG3829@1|root,COG3829@2|Bacteria,1TP0E@1239|Firmicutes,247MB@186801|Clostridia,36DY7@31979|Clostridiaceae	186801|Clostridia	KT	PFAM sigma-54 factor interaction domain-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,PAS,PAS_8,PAS_9,Sigma54_activat
k141_4913_6	1121324.CLIT_17c00160	1.14e-109	326.0	COG0697@1|root,COG0697@2|Bacteria,1TRKD@1239|Firmicutes,248I1@186801|Clostridia,25SDF@186804|Peptostreptococcaceae	186801|Clostridia	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
k141_4913_7	536227.CcarbDRAFT_2632	1.83e-33	118.0	COG0011@1|root,COG0011@2|Bacteria,1VBWM@1239|Firmicutes,25DPD@186801|Clostridia,36UDS@31979|Clostridiaceae	186801|Clostridia	S	Thiamine-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Thiamine_BP
k141_4913_8	1391647.AVSV01000036_gene854	1.77e-76	248.0	COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,1TP4F@1239|Firmicutes,248MM@186801|Clostridia,36DJS@31979|Clostridiaceae	186801|Clostridia	H	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate	ribD	-	1.1.1.193,3.5.4.26	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C,dCMP_cyt_deam_1
k141_4913_9	1540257.JQMW01000011_gene2227	2.83e-56	185.0	COG0307@1|root,COG0307@2|Bacteria,1V1EP@1239|Firmicutes,24FVK@186801|Clostridia,36GCB@31979|Clostridiaceae	186801|Clostridia	H	riboflavin synthase, alpha subunit	ribE	-	2.5.1.9	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00066	RC00958,RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	Lum_binding
k141_4913_10	1294142.CINTURNW_4361	1.09e-123	370.0	COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,1TPH9@1239|Firmicutes,248B0@186801|Clostridia,36E7D@31979|Clostridiaceae	186801|Clostridia	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	ribBA	-	3.5.4.25,4.1.99.12	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS10830	DHBP_synthase,GTP_cyclohydro2
k141_4913_11	1345695.CLSA_c14650	3.18e-68	210.0	COG0054@1|root,COG0054@2|Bacteria,1V1DA@1239|Firmicutes,24FRS@186801|Clostridia,36HYD@31979|Clostridiaceae	186801|Clostridia	H	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin	ribH	-	2.5.1.78	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R04457	RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	DMRL_synthase
k141_4913_12	1123405.AUMM01000012_gene2279	2.77e-36	127.0	COG1098@1|root,COG1098@2|Bacteria,1VASQ@1239|Firmicutes,4HKSW@91061|Bacilli,26PUB@186821|Sporolactobacillaceae	91061|Bacilli	J	Ribosomal protein S1-like RNA-binding domain	yugI	-	-	ko:K07570,ko:K07571	-	-	-	-	ko00000	-	-	-	S1
k141_4913_13	1286171.EAL2_c16660	4.15e-232	660.0	COG1757@1|root,COG1757@2|Bacteria,1TP8A@1239|Firmicutes,247V4@186801|Clostridia,25V8F@186806|Eubacteriaceae	186801|Clostridia	C	Na H antiporter	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_antiporter
k141_4913_14	1128398.Curi_c06150	0.0	1627.0	COG0060@1|root,COG0060@2|Bacteria,1TPS7@1239|Firmicutes,247XX@186801|Clostridia,267XD@186813|unclassified Clostridiales	186801|Clostridia	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1
k141_4913_15	697303.Thewi_1100	5.09e-57	186.0	COG1878@1|root,COG1878@2|Bacteria,1UFUJ@1239|Firmicutes,24HGD@186801|Clostridia,42F34@68295|Thermoanaerobacterales	186801|Clostridia	S	cyclase family	-	-	3.5.1.9	ko:K07130	ko00380,ko00630,ko01100,map00380,map00630,map01100	M00038	R00988,R01959,R04911	RC00263,RC00323	ko00000,ko00001,ko00002,ko01000	-	-	-	Cyclase
k141_4913_16	1121324.CLIT_23c00650	1.7e-115	355.0	COG0364@1|root,COG0364@2|Bacteria,1TPYF@1239|Firmicutes,24939@186801|Clostridia	186801|Clostridia	G	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone	zwf	-	1.1.1.363,1.1.1.49	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	M00004,M00006,M00008	R00835,R02736,R10907	RC00001,RC00066	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	G6PD_C,G6PD_N
k141_649_1	1219065.VPR01S_32_00110	7.74e-105	312.0	COG1502@1|root,COG1502@2|Bacteria,1RG9Z@1224|Proteobacteria,1S45X@1236|Gammaproteobacteria,1XUN2@135623|Vibrionales	135623|Vibrionales	I	PLD-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PLDc_2
k141_649_2	1219065.VPR01S_32_00100	0.0	2338.0	COG0714@1|root,COG0714@2|Bacteria,1NSN5@1224|Proteobacteria,1RPNN@1236|Gammaproteobacteria,1XW05@135623|Vibrionales	135623|Vibrionales	S	ATPase involved in DNA repair	-	-	-	-	-	-	-	-	-	-	-	-	AAA_5,DUF3686
k141_649_3	1190606.AJYG01000083_gene3170	2.6e-280	792.0	COG2268@1|root,COG2268@2|Bacteria,1P50K@1224|Proteobacteria,1RRHJ@1236|Gammaproteobacteria,1XUV8@135623|Vibrionales	135623|Vibrionales	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_649_4	1190606.AJYG01000083_gene3171	2.95e-71	222.0	2B2JA@1|root,31V4H@2|Bacteria,1QJQH@1224|Proteobacteria,1THRP@1236|Gammaproteobacteria,1XXBN@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF1449
k141_649_5	1515746.HR45_09320	3.93e-200	562.0	COG0620@1|root,COG0620@2|Bacteria,1MV2Z@1224|Proteobacteria,1RPTM@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	methionine synthase	-	-	-	-	-	-	-	-	-	-	-	-	Meth_synt_2
k141_649_6	1517681.HW45_20485	5.94e-114	342.0	COG1289@1|root,COG1289@2|Bacteria,1MUWE@1224|Proteobacteria,1RNFT@1236|Gammaproteobacteria,1XV9K@135623|Vibrionales	135623|Vibrionales	S	Fusaric acid resistance protein-like	-	-	-	-	-	-	-	-	-	-	-	-	FUSC,FUSC_2
k141_649_7	945543.VIBR0546_17218	1.09e-08	53.1	2AWY3@1|root,31NVR@2|Bacteria,1QKJE@1224|Proteobacteria,1TIPN@1236|Gammaproteobacteria,1XZF9@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_649_11	298386.PBPRB0088	1.14e-56	179.0	COG0589@1|root,COG0589@2|Bacteria,1MV6Y@1224|Proteobacteria,1RQQ7@1236|Gammaproteobacteria,1Y0V3@135623|Vibrionales	135623|Vibrionales	T	Universal stress protein family	-	-	-	ko:K06149	-	-	-	-	ko00000	-	-	-	Usp
k141_649_13	1280688.AUJB01000008_gene618	2.99e-167	478.0	COG3641@1|root,COG3641@2|Bacteria,1TS5F@1239|Firmicutes,247P0@186801|Clostridia,3NGMF@46205|Pseudobutyrivibrio	186801|Clostridia	S	Phosphotransferase system, EIIC	-	-	-	ko:K07035	-	-	-	-	ko00000	-	-	-	PTS_EIIC_2
k141_649_14	345073.VC395_A0812	0.0	1186.0	COG1327@1|root,COG1328@1|root,COG1327@2|Bacteria,COG1328@2|Bacteria,1MWMS@1224|Proteobacteria,1RNHS@1236|Gammaproteobacteria,1XU99@135623|Vibrionales	135623|Vibrionales	F	Ribonucleoside-triphosphate reductase	nrdD	-	1.1.98.6	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R11633,R11634,R11635,R11636	RC00613	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-cone,NRDD
k141_649_15	298386.PBPRA1845	1.33e-96	288.0	COG5654@1|root,COG5654@2|Bacteria,1PZ17@1224|Proteobacteria,1T1AH@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	RES	-	-	-	-	-	-	-	-	-	-	-	-	RES
k141_649_16	1006000.GKAS_04140	6.1e-54	172.0	COG5642@1|root,COG5642@2|Bacteria,1N1FN@1224|Proteobacteria,1T065@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF2384)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2384
k141_649_17	755731.Clo1100_2280	8.3e-23	96.7	COG1514@1|root,COG1514@2|Bacteria,1VEU2@1239|Firmicutes,24MTR@186801|Clostridia,36KR4@31979|Clostridiaceae	186801|Clostridia	J	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester	ligT	-	3.1.4.58	ko:K01975	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	LigT_PEase
k141_649_18	1348635.BBJY01000009_gene1502	1.42e-261	726.0	COG1288@1|root,COG1288@2|Bacteria,1MY1J@1224|Proteobacteria,1RS2M@1236|Gammaproteobacteria,1XSXV@135623|Vibrionales	135623|Vibrionales	S	C4-dicarboxylate anaerobic carrier	-	-	-	-	-	-	-	-	-	-	-	-	DcuC
k141_2352_1	658187.LDG_6202	7.2e-21	91.7	COG1012@1|root,COG1012@2|Bacteria,1MVGW@1224|Proteobacteria,1RN53@1236|Gammaproteobacteria,1JCDU@118969|Legionellales	118969|Legionellales	C	Aldehyde dehydrogenase family	ywdH	-	1.2.1.3,1.2.1.68	ko:K00128,ko:K00154	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
k141_4012_1	3218.PP1S189_77V6.2	4.47e-16	80.1	28HEW@1|root,2QPSY@2759|Eukaryota,37KNK@33090|Viridiplantae,3GDJJ@35493|Streptophyta	35493|Streptophyta	S	reductase	-	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	-	DapB_C,DapB_N
k141_4012_2	161156.JQKW01000006_gene1175	1.17e-29	120.0	COG3178@1|root,COG3178@2|Bacteria,2GHXN@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	JM	Ecdysteroid kinase	-	-	2.7.1.221	ko:K07102	ko00520,ko01100,map00520,map01100	-	R08968,R11024	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	APH,NTP_transferase
k141_1569_1	1121447.JONL01000006_gene186	1.67e-78	274.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,42M0W@68525|delta/epsilon subdivisions,2WIK8@28221|Deltaproteobacteria,2M8CQ@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	Diguanylate cyclase phosphodiesterase with PAS PAC sensor(S)	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
k141_1569_2	28176.CF66_0167	1.64e-99	313.0	COG0534@1|root,COG0534@2|Bacteria,1MUAM@1224|Proteobacteria,1RP5M@1236|Gammaproteobacteria,1XUSY@135623|Vibrionales	135623|Vibrionales	V	Multidrug efflux pump	norM	GO:0003674,GO:0005215,GO:0006810,GO:0006855,GO:0008150,GO:0015238,GO:0015893,GO:0022857,GO:0042221,GO:0042493,GO:0042891,GO:0042895,GO:0046677,GO:0050896,GO:0051179,GO:0051234,GO:0055085	-	ko:K03327	-	-	-	-	ko00000,ko02000	2.A.66.1	-	-	MatE
k141_3282_1	1116375.VEJY3_02915	4.06e-220	617.0	COG1070@1|root,COG1070@2|Bacteria,1N51F@1224|Proteobacteria,1RQX6@1236|Gammaproteobacteria,1XWBF@135623|Vibrionales	135623|Vibrionales	H	FGGY family of carbohydrate kinases, N-terminal domain	-	-	2.7.1.5	ko:K00848	ko00040,ko00051,ko01120,map00040,map00051,map01120	-	R01902,R03014	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	FGGY_C,FGGY_N
k141_3282_2	1348635.BBJY01000001_gene2662	2.62e-256	708.0	COG4806@1|root,COG4806@2|Bacteria,1MW7Z@1224|Proteobacteria,1RPDX@1236|Gammaproteobacteria,1XW3I@135623|Vibrionales	135623|Vibrionales	G	Catalyzes the formation of L-rhamnulose from L-rhamnose	-	-	5.3.1.14	ko:K01813	ko00051,ko01120,map00051,map01120	-	R02437	RC00434	ko00000,ko00001,ko01000	-	-	-	RhaA
k141_4318_1	879212.DespoDRAFT_01023	6.55e-71	227.0	COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,42MH9@68525|delta/epsilon subdivisions,2WJE0@28221|Deltaproteobacteria,2MIF7@213118|Desulfobacterales	28221|Deltaproteobacteria	U	General secretion pathway protein F	gspF	-	-	ko:K02455,ko:K02653	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSF
k141_4013_1	1121396.KB892935_gene3862	6.32e-48	174.0	COG2203@1|root,COG4191@1|root,COG2203@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MC4@68525|delta/epsilon subdivisions,2WIU5@28221|Deltaproteobacteria,2MJ3D@213118|Desulfobacterales	28221|Deltaproteobacteria	T	PAS fold	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS_3,PAS_9,Response_reg
k141_2353_1	675815.VOA_000568	1.18e-65	221.0	COG0834@1|root,COG2199@1|root,COG0834@2|Bacteria,COG2199@2|Bacteria,1NS3W@1224|Proteobacteria,1SKY3@1236|Gammaproteobacteria,1XSPX@135623|Vibrionales	135623|Vibrionales	ET	Bacterial extracellular solute-binding proteins, family 3	-	-	2.7.7.65	ko:K20957	ko05111,map05111	-	-	-	ko00000,ko00001,ko01000	-	-	-	GGDEF,SBP_bac_3
k141_4014_1	1313293.BAN_0061300	1.57e-43	160.0	COG0480@1|root,COG0480@2|Bacteria,2J5M8@203691|Spirochaetes	203691|Spirochaetes	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
k141_2600_1	1187848.AJYQ01000009_gene3054	3.22e-131	387.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,1XUI8@135623|Vibrionales	135623|Vibrionales	NT	methyl-accepting chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal,dCache_1
k141_2600_2	1136163.M565_ctg1P0350	1.76e-161	461.0	COG0628@1|root,COG0628@2|Bacteria,1MW0B@1224|Proteobacteria,1RPVP@1236|Gammaproteobacteria,1XV05@135623|Vibrionales	135623|Vibrionales	S	AI-2E family transporter	perM	-	-	ko:K03548	-	-	-	-	ko00000,ko02000	2.A.86.1	-	-	AI-2E_transport
k141_3734_1	1051646.VITU9109_04912	3.64e-243	706.0	COG1197@1|root,COG1197@2|Bacteria,1MUXG@1224|Proteobacteria,1RNCU@1236|Gammaproteobacteria,1XSMS@135623|Vibrionales	135623|Vibrionales	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
k141_3734_2	675814.VIC_001578	3.2e-68	213.0	2CHGH@1|root,32S61@2|Bacteria,1MZN3@1224|Proteobacteria,1S9S8@1236|Gammaproteobacteria,1XUJE@135623|Vibrionales	135623|Vibrionales	-	-	VV12079	-	-	-	-	-	-	-	-	-	-	-	-
k141_3734_3	674977.VMC_30990	5.06e-110	329.0	COG4591@1|root,COG4591@2|Bacteria,1MVV7@1224|Proteobacteria,1RMP9@1236|Gammaproteobacteria,1XSMT@135623|Vibrionales	135623|Vibrionales	M	COG4591 ABC-type transport system, involved in lipoprotein release, permease component	lolC	-	-	ko:K09808	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125	-	-	FtsX,MacB_PCD
k141_4319_1	1267534.KB906754_gene3199	3.48e-12	75.1	COG0438@1|root,COG0438@2|Bacteria,3Y6U5@57723|Acidobacteria,2JM7K@204432|Acidobacteriia	204432|Acidobacteriia	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
k141_4015_2	1304885.AUEY01000005_gene828	3.93e-81	244.0	COG1329@1|root,COG1329@2|Bacteria,1MWI2@1224|Proteobacteria,42RXS@68525|delta/epsilon subdivisions,2WNA0@28221|Deltaproteobacteria,2MJTK@213118|Desulfobacterales	28221|Deltaproteobacteria	K	PFAM transcription factor CarD	-	-	-	ko:K07736	-	-	-	-	ko00000,ko03000	-	-	-	CarD_CdnL_TRCF
k141_2601_1	307480.IW16_21040	1.58e-117	361.0	COG0178@1|root,COG0178@2|Bacteria,4NJCU@976|Bacteroidetes,1HZ64@117743|Flavobacteriia,3ZNRV@59732|Chryseobacterium	976|Bacteroidetes	L	ATPases associated with a variety of cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
k141_4320_1	1121289.JHVL01000008_gene1238	1.84e-122	355.0	COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia,36FGA@31979|Clostridiaceae	186801|Clostridia	C	Electron transfer flavoprotein	etfB1	-	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
k141_4016_1	563040.Saut_2143	1.62e-29	121.0	COG0608@1|root,COG0608@2|Bacteria,1MU1M@1224|Proteobacteria,42MYF@68525|delta/epsilon subdivisions,2YMXD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Single-stranded-DNA-specific exonuclease (RecJ)	recJ	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
k141_2602_1	177437.HRM2_36610	2.89e-71	228.0	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,42MSR@68525|delta/epsilon subdivisions,2WIXG@28221|Deltaproteobacteria,2MIJC@213118|Desulfobacterales	28221|Deltaproteobacteria	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
k141_650_1	1121396.KB893085_gene344	1.15e-269	826.0	COG1020@1|root,COG3321@1|root,COG1020@2|Bacteria,COG3321@2|Bacteria,1QK4F@1224|Proteobacteria,42Z5Y@68525|delta/epsilon subdivisions,2X8JI@28221|Deltaproteobacteria,2MMZD@213118|Desulfobacterales	28221|Deltaproteobacteria	Q	Condensation domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_1,Condensation,KAsynt_C_assoc,KR,Ketoacyl-synt_C,PP-binding,PS-DH,ketoacyl-synt
k141_911_2	1348635.BBJY01000012_gene1155	0.0	1004.0	COG0768@1|root,COG0768@2|Bacteria,1MV8C@1224|Proteobacteria,1RN9H@1236|Gammaproteobacteria,1XTJ2@135623|Vibrionales	135623|Vibrionales	M	Catalyzes cross-linking of the peptidoglycan cell wall	mrdA	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	PBP_dimer,Transpeptidase
k141_911_4	674977.VMC_10250	8.13e-113	332.0	COG0797@1|root,COG0797@2|Bacteria,1MZ8S@1224|Proteobacteria,1RMCG@1236|Gammaproteobacteria,1XSTT@135623|Vibrionales	135623|Vibrionales	M	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides	rlpA	-	-	ko:K03642	-	-	-	-	ko00000	-	-	-	DPBB_1,SPOR
k141_911_7	243277.VC_0944	2.8e-116	337.0	COG0321@1|root,COG0321@2|Bacteria,1MU6A@1224|Proteobacteria,1RMXQ@1236|Gammaproteobacteria,1XT77@135623|Vibrionales	135623|Vibrionales	H	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate	lipB	GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0016874,GO:0016879,GO:0016979,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0071704,GO:0072330,GO:0140096,GO:1901360,GO:1901362,GO:1901564,GO:1901576	2.3.1.181	ko:K03801	ko00785,ko01100,map00785,map01100	-	R07766,R07769	RC00039,RC00992,RC02867	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB
k141_911_8	672.VV93_v1c08370	4.2e-215	595.0	COG0320@1|root,COG0320@2|Bacteria,1MVRD@1224|Proteobacteria,1RMAT@1236|Gammaproteobacteria,1XUN7@135623|Vibrionales	135623|Vibrionales	H	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives	lipA	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576	2.8.1.8	ko:K03644	ko00785,ko01100,map00785,map01100	-	R07767,R07768	RC01978	ko00000,ko00001,ko01000	-	-	-	LIAS_N,Radical_SAM
k141_911_9	243277.VC_0942	7.47e-50	160.0	2AW92@1|root,31N4D@2|Bacteria,1QJVU@1224|Proteobacteria,1THXF@1236|Gammaproteobacteria,1XXTJ@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_3736_1	439235.Dalk_0094	1.33e-19	92.8	COG0840@1|root,COG4564@1|root,COG0840@2|Bacteria,COG4564@2|Bacteria,1MU9B@1224|Proteobacteria,42PCY@68525|delta/epsilon subdivisions,2WJCR@28221|Deltaproteobacteria,2MMSU@213118|Desulfobacterales	28221|Deltaproteobacteria	NT	Single cache domain 3	-	-	-	ko:K03406,ko:K13487	ko02020,ko02025,ko02030,map02020,map02025,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	Cache_3-Cache_2,HAMP,MCPsignal
k141_2354_1	1304284.L21TH_2353	1.04e-157	454.0	COG0416@1|root,COG0416@2|Bacteria,1TPY8@1239|Firmicutes,248BX@186801|Clostridia,36EUZ@31979|Clostridiaceae	186801|Clostridia	I	PFAM fatty acid synthesis plsX protein	grdD	-	1.21.4.2,1.21.4.3,1.21.4.4	ko:K21576	-	-	-	-	ko00000,ko01000	-	-	-	FA_synthesis
k141_2354_2	1304284.L21TH_2354	2.34e-278	771.0	COG0332@1|root,COG0332@2|Bacteria,1TQSB@1239|Firmicutes,2499C@186801|Clostridia,36FF2@31979|Clostridiaceae	186801|Clostridia	I	3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III	grdC	-	1.21.4.2,1.21.4.3,1.21.4.4	ko:K21577	-	-	-	-	ko00000,ko01000	-	-	-	ACP_syn_III
k141_1570_2	1121396.KB893104_gene1782	5.1e-122	366.0	COG3464@1|root,COG3464@2|Bacteria,1Q4UF@1224|Proteobacteria,42ZWR@68525|delta/epsilon subdivisions,2WV9E@28221|Deltaproteobacteria,2MNHQ@213118|Desulfobacterales	28221|Deltaproteobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_1570_3	933262.AXAM01000034_gene1578	9.51e-129	375.0	28J8Y@1|root,2Z943@2|Bacteria,1REXC@1224|Proteobacteria,43DCS@68525|delta/epsilon subdivisions,2X8IT@28221|Deltaproteobacteria,2MK0X@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4338)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4338
k141_4322_1	1121878.AUGL01000013_gene2898	1.76e-50	166.0	COG0842@1|root,COG0842@2|Bacteria,1MUH1@1224|Proteobacteria	1224|Proteobacteria	V	transport, permease protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane
k141_4322_2	1121918.ARWE01000001_gene2028	1.91e-56	185.0	COG1131@1|root,COG1131@2|Bacteria,1MUW7@1224|Proteobacteria,43AE0@68525|delta/epsilon subdivisions,2WK0E@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	PFAM ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
k141_3737_1	1121935.AQXX01000129_gene1792	6.24e-59	201.0	COG4166@1|root,COG4166@2|Bacteria,1MUVU@1224|Proteobacteria,1RMA1@1236|Gammaproteobacteria,1XITH@135619|Oceanospirillales	135619|Oceanospirillales	E	ABC-type oligopeptide transport system, periplasmic component	-	-	-	ko:K13893	ko02010,map02010	M00349	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.21,3.A.1.5.24	-	-	SBP_bac_5
k141_1308_1	1219077.VAZ01S_045_00050	2.22e-88	266.0	COG3022@1|root,COG3022@2|Bacteria,1MUAF@1224|Proteobacteria,1RMTD@1236|Gammaproteobacteria,1XUFU@135623|Vibrionales	135623|Vibrionales	S	Belongs to the UPF0246 family	yaaA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0033194,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:1901700	-	ko:K09861	-	-	-	-	ko00000	-	-	-	H2O2_YaaD
k141_663_8	675813.VIB_000519	1.29e-176	507.0	COG1012@1|root,COG1012@2|Bacteria,1MV2I@1224|Proteobacteria,1RPQW@1236|Gammaproteobacteria,1XTD0@135623|Vibrionales	135623|Vibrionales	C	Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate	astD	GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016491,GO:0016620,GO:0016903,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0055114,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	1.2.1.71	ko:K06447	ko00330,ko01100,map00330,map01100	-	R05049	RC00080	ko00000,ko00001,ko01000	-	-	-	Aldedh
k141_4757_1	1232410.KI421418_gene2366	5.23e-130	392.0	COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,42N8M@68525|delta/epsilon subdivisions,2WJRT@28221|Deltaproteobacteria,43SXK@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	nrdJ	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_lgC,Ribonuc_red_lgN,TSCPD
k141_5029_1	1232437.KL661971_gene4816	1.44e-95	298.0	COG1196@1|root,COG1196@2|Bacteria,1MVMQ@1224|Proteobacteria,42NF4@68525|delta/epsilon subdivisions,2WIMP@28221|Deltaproteobacteria,2MJAB@213118|Desulfobacterales	28221|Deltaproteobacteria	D	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_4758_1	1280685.AUKC01000053_gene1398	3.17e-26	111.0	COG2770@1|root,COG5002@1|root,COG2770@2|Bacteria,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,247VG@186801|Clostridia,4BXA8@830|Butyrivibrio	186801|Clostridia	T	GHKL domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
k141_1589_1	1121405.dsmv_2060	2.13e-61	197.0	COG2834@1|root,COG2834@2|Bacteria,1R5U8@1224|Proteobacteria,42MIS@68525|delta/epsilon subdivisions,2WMK7@28221|Deltaproteobacteria,2MJNM@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Outer membrane lipoprotein-sorting protein	-	-	-	-	-	-	-	-	-	-	-	-	LolA_like
k141_5030_1	1410653.JHVC01000010_gene3528	8.18e-118	348.0	COG0786@1|root,COG0786@2|Bacteria,1TS2B@1239|Firmicutes,24CRX@186801|Clostridia,36EU3@31979|Clostridiaceae	186801|Clostridia	E	glutamate:sodium symporter activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_1591_1	1304885.AUEY01000052_gene1561	1.17e-23	94.4	COG1100@1|root,COG1100@2|Bacteria,1R6NS@1224|Proteobacteria,42NIX@68525|delta/epsilon subdivisions,2WJ44@28221|Deltaproteobacteria,2MI9K@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Gtr1/RagA G protein conserved region	mglA	GO:0008150,GO:0032879,GO:0032880,GO:0050789,GO:0065007	-	ko:K06883	-	-	-	-	ko00000	-	-	-	Arf,Ras
k141_1591_2	1304885.AUEY01000052_gene1562	1.08e-60	189.0	COG2018@1|root,COG2018@2|Bacteria,1RDN5@1224|Proteobacteria,42S13@68525|delta/epsilon subdivisions,2WNKB@28221|Deltaproteobacteria,2MKA4@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Roadblock/LC7 domain	mglB	-	-	-	-	-	-	-	-	-	-	-	Robl_LC7
k141_2623_1	1219065.VPR01S_10_00620	4.3e-248	702.0	COG4775@1|root,COG4775@2|Bacteria,1MU0D@1224|Proteobacteria,1RMAP@1236|Gammaproteobacteria,1XTPE@135623|Vibrionales	135623|Vibrionales	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamA	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
k141_2623_2	1280001.BAOA01000081_gene2986	2.21e-123	366.0	COG0750@1|root,COG0750@2|Bacteria,1MU91@1224|Proteobacteria,1RMIX@1236|Gammaproteobacteria,1XUCN@135623|Vibrionales	135623|Vibrionales	M	Zinc metalloprotease	rseP	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_M50
k141_4759_3	945550.VISI1226_19214	1.46e-59	184.0	COG2965@1|root,COG2965@2|Bacteria,1RHIE@1224|Proteobacteria,1S6H5@1236|Gammaproteobacteria,1XXV4@135623|Vibrionales	135623|Vibrionales	L	Binds single-stranded DNA at the primosome assembly site (PAS)	priB	GO:0000228,GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005657,GO:0005658,GO:0005694,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006269,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0018130,GO:0019438,GO:0030880,GO:0030894,GO:0031974,GO:0031981,GO:0032774,GO:0032991,GO:0032993,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043596,GO:0043601,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044446,GO:0044454,GO:0044464,GO:0046483,GO:0055029,GO:0061695,GO:0070013,GO:0071704,GO:0090304,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234	-	ko:K02686	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	SSB
k141_2939_1	886293.Sinac_6646	3.15e-47	192.0	COG1196@1|root,COG3264@1|root,COG1196@2|Bacteria,COG3264@2|Bacteria,2IY5W@203682|Planctomycetes	203682|Planctomycetes	M	COG3264 Small-conductance mechanosensitive channel	-	-	-	ko:K22051	-	-	-	-	ko00000,ko02000	1.A.23.1.2,1.A.23.1.3	-	-	MS_channel
k141_2939_2	316275.VSAL_II1024	9.46e-272	749.0	COG1486@1|root,COG1486@2|Bacteria,1NI6G@1224|Proteobacteria,1RPG8@1236|Gammaproteobacteria,1XSYS@135623|Vibrionales	135623|Vibrionales	G	COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases	-	-	3.2.1.86	ko:K01222	ko00010,ko00500,map00010,map00500	-	R00839,R05133,R05134	RC00049,RC00171,RC00714	ko00000,ko00001,ko01000	-	GT4	-	Glyco_hydro_4,Glyco_hydro_4C
k141_2939_3	104623.Ser39006_04125	5.65e-167	474.0	COG0583@1|root,COG0583@2|Bacteria,1MWY0@1224|Proteobacteria,1RNMN@1236|Gammaproteobacteria,402G9@613|Serratia	1236|Gammaproteobacteria	K	LysR substrate binding domain	-	-	-	ko:K03566,ko:K13636	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_1,LysR_substrate
k141_2939_4	674977.VMC_08780	8.83e-23	103.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,1XSRT@135623|Vibrionales	135623|Vibrionales	NT	methyl-accepting chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal,dCache_1
k141_1592_1	96561.Dole_2570	8.15e-302	840.0	COG1328@1|root,COG1328@2|Bacteria,1MWMS@1224|Proteobacteria,42M8V@68525|delta/epsilon subdivisions,2WJ7S@28221|Deltaproteobacteria,2MHTW@213118|Desulfobacterales	28221|Deltaproteobacteria	F	anaerobic ribonucleoside-triphosphate reductase	nrdD	-	1.1.98.6	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R11633,R11634,R11635,R11636	RC00613	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-cone,NRDD
k141_1322_1	1122211.JMLW01000007_gene109	3.93e-74	225.0	COG3600@1|root,COG3600@2|Bacteria,1N78U@1224|Proteobacteria,1SF6A@1236|Gammaproteobacteria,1XQHR@135619|Oceanospirillales	135619|Oceanospirillales	S	Protein of unknown function (DUF4065)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4065
k141_1322_2	1117315.AHCA01000012_gene2690	2.08e-59	204.0	COG2357@1|root,COG2357@2|Bacteria,1RBSQ@1224|Proteobacteria,1RR52@1236|Gammaproteobacteria,2Q44D@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	S	Region found in RelA / SpoT proteins	-	-	-	-	-	-	-	-	-	-	-	-	RelA_SpoT
k141_1322_4	641143.HMPREF9331_01581	8.91e-31	119.0	2EYBA@1|root,33Z6I@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_2035_2	55601.VANGNB10_cII0078	1.12e-131	379.0	COG3455@1|root,COG3455@2|Bacteria,1MU13@1224|Proteobacteria,1S2PW@1236|Gammaproteobacteria,1XT7V@135623|Vibrionales	135623|Vibrionales	N	VI Secretion	vasF	-	-	ko:K11892	ko03070,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	DotU
k141_2035_3	675815.VOA_001302	2.1e-44	160.0	COG0542@1|root,COG0542@2|Bacteria,1MVBH@1224|Proteobacteria,1RMZH@1236|Gammaproteobacteria,1XTVD@135623|Vibrionales	135623|Vibrionales	O	Belongs to the ClpA ClpB family	-	-	-	ko:K11907	ko02025,ko03070,map02025,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
k141_4761_2	439235.Dalk_4652	1.99e-13	69.3	COG0301@1|root,COG1293@1|root,COG0301@2|Bacteria,COG1293@2|Bacteria,1N1R1@1224|Proteobacteria,42MQ9@68525|delta/epsilon subdivisions,2WJPN@28221|Deltaproteobacteria,2MICH@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Thiamine biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF814,ThiI
k141_1325_1	1265505.ATUG01000002_gene1000	4.72e-76	237.0	COG1270@1|root,COG1270@2|Bacteria,1MURM@1224|Proteobacteria,42PDX@68525|delta/epsilon subdivisions,2WKH4@28221|Deltaproteobacteria,2MIRQ@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group	cobD	-	6.3.1.10	ko:K02227	ko00860,ko01100,map00860,map01100	M00122	R06529,R07302	RC00090,RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	CobD_Cbib
k141_5272_1	701176.VIBRN418_18733	1.75e-20	95.9	COG3501@1|root,COG3501@2|Bacteria,1MU7Q@1224|Proteobacteria,1RMZS@1236|Gammaproteobacteria,1XUHW@135623|Vibrionales	135623|Vibrionales	M	protein conserved in bacteria	-	GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0006464,GO:0006807,GO:0006996,GO:0007010,GO:0007015,GO:0008144,GO:0008150,GO:0008152,GO:0008154,GO:0009405,GO:0009987,GO:0016043,GO:0016874,GO:0016879,GO:0016881,GO:0017076,GO:0018149,GO:0018153,GO:0018193,GO:0018199,GO:0018205,GO:0018262,GO:0018995,GO:0019538,GO:0022411,GO:0030029,GO:0030036,GO:0030042,GO:0030430,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032984,GO:0033643,GO:0033646,GO:0035639,GO:0036094,GO:0036211,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0043624,GO:0043656,GO:0043657,GO:0043933,GO:0044215,GO:0044216,GO:0044217,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044419,GO:0046872,GO:0051261,GO:0051704,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:0097435,GO:1901265,GO:1901363,GO:1901564	-	ko:K11904	ko03070,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	Phage_GPD
k141_5272_3	270374.MELB17_06294	1.18e-29	136.0	2EW5T@1|root,33PIW@2|Bacteria,1N4PB@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_5272_7	574966.KB898646_gene3248	6.39e-18	84.3	2A07X@1|root,30NB4@2|Bacteria,1N1WT@1224|Proteobacteria,1S9GH@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF3592)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3592
k141_5272_8	29495.EA26_04085	5.57e-149	426.0	COG0627@1|root,COG0627@2|Bacteria,1MUID@1224|Proteobacteria,1RMR3@1236|Gammaproteobacteria,1XUG1@135623|Vibrionales	135623|Vibrionales	S	Serine hydrolase involved in the detoxification of formaldehyde	yeiG	-	3.1.2.12	ko:K01070	ko00680,ko01120,ko01200,map00680,map01120,map01200	-	R00527	RC00167,RC00320	ko00000,ko00001,ko01000	-	CE1	-	Esterase
k141_5272_10	675813.VIB_001786	6.95e-138	397.0	COG0583@1|root,COG0583@2|Bacteria,1MW16@1224|Proteobacteria,1RS6U@1236|Gammaproteobacteria,1XU3Y@135623|Vibrionales	135623|Vibrionales	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
k141_5272_11	61647.LG71_06650	6.2e-254	706.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,1RMBQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	belongs to the aldehyde dehydrogenase family	-	-	1.2.1.16,1.2.1.20,1.2.1.24,1.2.1.79	ko:K00135,ko:K08324	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	M00027	R00713,R00714,R02401	RC00080	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
k141_5347_14	1391647.AVSV01000028_gene284	2.88e-19	84.7	2E70J@1|root,331JD@2|Bacteria,1VGGS@1239|Firmicutes,24JJ2@186801|Clostridia,36JT3@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_5347_19	1121324.CLIT_10c03380	1.96e-21	103.0	2BBX0@1|root,325FF@2|Bacteria,1URHA@1239|Firmicutes,24X0N@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_40_2	1051646.VITU9109_19125	1.9e-74	225.0	2CB6X@1|root,2ZTSF@2|Bacteria,1P8T9@1224|Proteobacteria,1STHQ@1236|Gammaproteobacteria,1XX1M@135623|Vibrionales	135623|Vibrionales	S	Protein of unknown function (DUF3069)	VPA0928	-	-	-	-	-	-	-	-	-	-	-	DUF3069
k141_40_3	1348635.BBJY01000013_gene1067	1.5e-225	630.0	COG1301@1|root,COG1301@2|Bacteria,1MU0Q@1224|Proteobacteria,1RMEN@1236|Gammaproteobacteria,1XU7P@135623|Vibrionales	135623|Vibrionales	U	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family	-	-	-	-	-	-	-	-	-	-	-	-	SDF
k141_4107_1	439235.Dalk_1689	1.8e-43	164.0	COG2202@1|root,COG2204@1|root,COG4191@1|root,COG2202@2|Bacteria,COG2204@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MFW@68525|delta/epsilon subdivisions,2WKMP@28221|Deltaproteobacteria,2MI6S@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_3,Response_reg
k141_2739_1	675813.VIB_001396	2.36e-147	430.0	COG5421@1|root,COG5421@2|Bacteria,1R25F@1224|Proteobacteria,1RZQP@1236|Gammaproteobacteria,1XV94@135623|Vibrionales	135623|Vibrionales	L	Domain of unknown function (DUF4277)	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DUF4277
k141_361_1	617140.AJZE01000057_gene2073	0.0	1385.0	COG1074@1|root,COG1074@2|Bacteria,1MUTF@1224|Proteobacteria,1RPC6@1236|Gammaproteobacteria,1XTTM@135623|Vibrionales	135623|Vibrionales	L	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA	recB	-	3.1.11.5	ko:K03582	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
k141_361_2	675816.VIA_002189	3.49e-171	520.0	COG1330@1|root,COG1330@2|Bacteria,1MWTI@1224|Proteobacteria,1RNT0@1236|Gammaproteobacteria,1XTXU@135623|Vibrionales	135623|Vibrionales	L	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity	recC	-	3.1.11.5	ko:K03583	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_V_gamma
k141_1389_2	223926.28808749	5.17e-273	750.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,1RYD1@1236|Gammaproteobacteria,1XTEW@135623|Vibrionales	135623|Vibrionales	JKL	Belongs to the DEAD box helicase family	-	-	-	-	-	-	-	-	-	-	-	-	DEAD,Helicase_C
k141_709_2	1304885.AUEY01000004_gene923	4.52e-173	539.0	COG0834@1|root,COG2203@1|root,COG5002@1|root,COG0834@2|Bacteria,COG2203@2|Bacteria,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,43CS7@68525|delta/epsilon subdivisions,2X7ZW@28221|Deltaproteobacteria,2MPMK@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_7,PAS_8,PAS_9,Response_reg,SBP_bac_3,sCache_3_2
k141_364_1	1265505.ATUG01000003_gene24	1.65e-88	273.0	COG0436@1|root,COG0436@2|Bacteria,1QW10@1224|Proteobacteria,42MQA@68525|delta/epsilon subdivisions,2WJDK@28221|Deltaproteobacteria,2MJ7D@213118|Desulfobacterales	28221|Deltaproteobacteria	E	PFAM aminotransferase class I and II	bamJ	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
k141_2740_4	675814.VIC_001707	4.02e-294	809.0	COG0733@1|root,COG0733@2|Bacteria,1MUZJ@1224|Proteobacteria,1RPCT@1236|Gammaproteobacteria,1XU8H@135623|Vibrionales	135623|Vibrionales	U	Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family	-	-	-	ko:K03308	-	-	-	-	ko00000	2.A.22.4,2.A.22.5	-	-	SNF
k141_710_1	1397284.AYMN01000070_gene2136	1.22e-20	95.1	COG4388@1|root,COG4388@2|Bacteria,1RA2J@1224|Proteobacteria,1RZEI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Mu-like prophage I protein	-	-	-	-	-	-	-	-	-	-	-	-	Mu-like_Pro
k141_43_2	714083.JH370377_gene1931	0.000383	51.2	COG0683@1|root,COG0683@2|Bacteria,2GM00@201174|Actinobacteria,4FMUU@85023|Microbacteriaceae	201174|Actinobacteria	E	Receptor family ligand binding region	livK	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
k141_43_3	8081.XP_008397876.1	8.3e-73	246.0	COG2896@1|root,KOG2876@2759|Eukaryota,38F0A@33154|Opisthokonta,3B9J0@33208|Metazoa,3D129@33213|Bilateria,4862I@7711|Chordata,48Y19@7742|Vertebrata,49VGC@7898|Actinopterygii	33208|Metazoa	H	Molybdenum cofactor	MOCS1	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006732,GO:0006753,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009144,GO:0009150,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0016829,GO:0016830,GO:0016849,GO:0018130,GO:0019538,GO:0019637,GO:0019693,GO:0019720,GO:0032324,GO:0034641,GO:0042278,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046039,GO:0046128,GO:0046483,GO:0048037,GO:0051186,GO:0051188,GO:0051189,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0061798,GO:0061799,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657	4.1.99.22,4.6.1.17	ko:K20967	ko00790,ko01100,map00790,map01100	-	R09394,R11372	RC03420,RC03425	ko00000,ko00001,ko01000	-	-	-	Fer4_12,MoaC,Mob_synth_C,Radical_SAM
k141_43_4	439235.Dalk_0158	4.23e-20	89.7	COG0243@1|root,COG0243@2|Bacteria,1NR6J@1224|Proteobacteria,42NEV@68525|delta/epsilon subdivisions,2WJD0@28221|Deltaproteobacteria,2MHX6@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Molybdopterin oxidoreductase Fe4S4 domain	-	-	-	-	-	-	-	-	-	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
k141_2048_1	675814.VIC_004455	9.15e-71	215.0	COG1607@1|root,COG1607@2|Bacteria,1MZAZ@1224|Proteobacteria,1SA9N@1236|Gammaproteobacteria,1XWWY@135623|Vibrionales	135623|Vibrionales	I	COG1607 Acyl-CoA hydrolase	yciA	-	-	ko:K10806	ko01040,map01040	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	4HBT
k141_2048_2	1187848.AJYQ01000066_gene3634	5.35e-52	165.0	COG2350@1|root,COG2350@2|Bacteria,1MZ9Z@1224|Proteobacteria,1S8UC@1236|Gammaproteobacteria,1XXWF@135623|Vibrionales	135623|Vibrionales	S	protein conserved in bacteria	yciI	-	-	ko:K09780	-	-	-	-	ko00000	-	-	-	YCII
k141_2048_3	672.VV93_v1c11280	4.86e-37	130.0	2B0AA@1|root,31SMA@2|Bacteria,1QJXS@1224|Proteobacteria,1THZX@1236|Gammaproteobacteria,1XY1G@135623|Vibrionales	135623|Vibrionales	S	Type II secretion system (T2SS) pilotin, S protein	-	-	-	-	-	-	-	-	-	-	-	-	T2SSS_2
k141_2048_4	1280001.BAOA01000117_gene73	5.41e-187	523.0	COG0583@1|root,COG0583@2|Bacteria,1MUIX@1224|Proteobacteria,1RRF3@1236|Gammaproteobacteria,1XTEB@135623|Vibrionales	135623|Vibrionales	K	COG0583 Transcriptional regulator	metR	-	-	ko:K03576	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,LysR_substrate
k141_2048_5	998088.B565_1650	5.97e-23	89.4	2EBQJ@1|root,335QK@2|Bacteria,1NF4K@1224|Proteobacteria,1SFHI@1236|Gammaproteobacteria,1Y4XX@135624|Aeromonadales	135624|Aeromonadales	S	Domain of unknown function (DUF4250)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4250
k141_2048_6	1219076.N646_4162	1.43e-65	207.0	COG2606@1|root,COG2606@2|Bacteria,1N10Y@1224|Proteobacteria,1SAQE@1236|Gammaproteobacteria,1XWYK@135623|Vibrionales	135623|Vibrionales	S	Aminoacyl-tRNA editing domain	-	-	-	ko:K19055	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA_edit
k141_2048_7	290402.Cbei_2056	0.0	1322.0	COG0431@1|root,COG1053@1|root,COG3976@1|root,COG0431@2|Bacteria,COG1053@2|Bacteria,COG3976@2|Bacteria,1TPAR@1239|Firmicutes,247SY@186801|Clostridia,36DR3@31979|Clostridiaceae	186801|Clostridia	C	PFAM fumarate reductase succinate dehydrogenase flavoprotein domain protein	-	-	1.3.5.1,1.3.5.4	ko:K00239,ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,ko05134,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020,map05134	M00009,M00011,M00149,M00150,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,FMN_bind,FMN_red
k141_2048_8	1449050.JNLE01000003_gene1952	9.71e-103	301.0	COG0431@1|root,COG0431@2|Bacteria,1TT2S@1239|Firmicutes,247MY@186801|Clostridia,36FV1@31979|Clostridiaceae	186801|Clostridia	S	NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
k141_2048_9	1321778.HMPREF1982_04146	7.15e-135	392.0	COG0583@1|root,COG0583@2|Bacteria,1V0QD@1239|Firmicutes,24CF3@186801|Clostridia	186801|Clostridia	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
k141_2048_10	290402.Cbei_2053	9.15e-140	404.0	COG1477@1|root,COG1477@2|Bacteria,1TR9C@1239|Firmicutes,248KJ@186801|Clostridia,36DZZ@31979|Clostridiaceae	186801|Clostridia	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	-	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
k141_2048_11	1348635.BBJY01000017_gene4105	0.0	1188.0	COG1032@1|root,COG1032@2|Bacteria,1MUG3@1224|Proteobacteria,1RN9V@1236|Gammaproteobacteria,1XT35@135623|Vibrionales	135623|Vibrionales	C	UPF0313 protein	ygiQ	-	-	-	-	-	-	-	-	-	-	-	DUF3362,Radical_SAM,Radical_SAM_N
k141_2048_12	1219065.VPR01S_01_04530	6.33e-214	596.0	COG1932@1|root,COG1932@2|Bacteria,1MUB5@1224|Proteobacteria,1RMKU@1236|Gammaproteobacteria,1XSV4@135623|Vibrionales	135623|Vibrionales	E	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine	serC	GO:0003674,GO:0003824,GO:0004648,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006563,GO:0006564,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.6.1.52	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	M00020,M00124	R04173,R05085	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
k141_2048_14	345073.VC395_1223	4.43e-269	759.0	COG0664@1|root,COG0784@1|root,COG4191@1|root,COG0664@2|Bacteria,COG0784@2|Bacteria,COG4191@2|Bacteria,1R97I@1224|Proteobacteria,1RNJ8@1236|Gammaproteobacteria,1XSZK@135623|Vibrionales	135623|Vibrionales	T	COG0642 Signal transduction histidine kinase	VP1245	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg,cNMP_binding
k141_2048_15	1348635.BBJY01000017_gene4101	2.67e-77	234.0	COG0784@1|root,COG0784@2|Bacteria,1MYIP@1224|Proteobacteria,1S89X@1236|Gammaproteobacteria,1XWV8@135623|Vibrionales	135623|Vibrionales	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
k141_2048_16	945550.VISI1226_21950	7.62e-87	259.0	2B0QJ@1|root,31T2K@2|Bacteria,1QJDY@1224|Proteobacteria,1THD8@1236|Gammaproteobacteria,1XU73@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_2048_17	675815.VOA_000461	1.6e-53	176.0	COG3070@1|root,COG3070@2|Bacteria,1QJGH@1224|Proteobacteria,1THG9@1236|Gammaproteobacteria,1XVKC@135623|Vibrionales	135623|Vibrionales	K	COG3070 Regulator of competence-specific genes	VV1446	GO:0006810,GO:0007154,GO:0008150,GO:0009290,GO:0009292,GO:0009294,GO:0009605,GO:0009987,GO:0009991,GO:0015931,GO:0030420,GO:0031668,GO:0044764,GO:0050657,GO:0050896,GO:0051027,GO:0051179,GO:0051234,GO:0051704,GO:0051716,GO:0071496,GO:0071702,GO:0071705,GO:0098657	-	ko:K07343	-	-	-	-	ko00000	-	-	-	TfoX_C,TfoX_N
k141_2048_18	675813.VIB_001049	8.56e-114	338.0	COG1639@1|root,COG1639@2|Bacteria,1N7EN@1224|Proteobacteria,1RT8G@1236|Gammaproteobacteria,1XUWE@135623|Vibrionales	135623|Vibrionales	T	Signal transduction protein	-	-	-	-	-	-	-	-	-	-	-	-	HDOD
k141_2048_19	1492922.GY26_04195	9.95e-56	189.0	COG2431@1|root,COG2431@2|Bacteria,1MYMF@1224|Proteobacteria,1RP7N@1236|Gammaproteobacteria,1JA1G@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Pfam:DUF340	ybjE	GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006855,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015174,GO:0015179,GO:0015189,GO:0015238,GO:0015318,GO:0015562,GO:0015661,GO:0015711,GO:0015802,GO:0015807,GO:0015849,GO:0015893,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0034639,GO:0042221,GO:0042493,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098655,GO:0098656,GO:1902022,GO:1902475,GO:1903401,GO:1903825,GO:1905039,GO:1990822	-	-	-	-	-	-	-	-	-	-	Lys_export
k141_2048_20	945550.VISI1226_04694	2.85e-284	790.0	COG0076@1|root,COG0076@2|Bacteria,1MWUX@1224|Proteobacteria,1RQ8G@1236|Gammaproteobacteria,1XTEY@135623|Vibrionales	135623|Vibrionales	E	COG0076 Glutamate decarboxylase and related PLP-dependent proteins	-	GO:0003674,GO:0003824,GO:0004068,GO:0016829,GO:0016830,GO:0016831	4.1.1.15	ko:K01580	ko00250,ko00410,ko00430,ko00650,ko01100,ko01110,ko01120,ko02024,ko04727,ko04940,map00250,map00410,map00430,map00650,map01100,map01110,map01120,map02024,map04727,map04940	M00027	R00261,R00489,R01682,R02466	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Pyridoxal_deC
k141_2048_21	243277.VC_1148	2.28e-189	527.0	COG1737@1|root,COG1737@2|Bacteria,1MV3U@1224|Proteobacteria,1RNC4@1236|Gammaproteobacteria,1XSSF@135623|Vibrionales	135623|Vibrionales	K	COG1737 Transcriptional regulators	hexR	-	-	ko:K19337	-	-	-	-	ko00000,ko03000	-	-	-	HTH_6,SIS
k141_2048_22	55601.VANGNB10_cI1048	4.99e-189	537.0	COG1454@1|root,COG1454@2|Bacteria,1MVPH@1224|Proteobacteria,1S1W6@1236|Gammaproteobacteria,1XTZE@135623|Vibrionales	135623|Vibrionales	C	alcohol dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Fe-ADH
k141_2048_23	243277.VC_1146	4.7e-51	162.0	COG0695@1|root,COG0695@2|Bacteria,1RGZ7@1224|Proteobacteria,1S5ZP@1236|Gammaproteobacteria,1XXU0@135623|Vibrionales	135623|Vibrionales	O	COG0695 Glutaredoxin and related proteins	grxA	-	-	ko:K03674	-	-	-	-	ko00000,ko03110	-	-	-	Glutaredoxin
k141_2048_24	55601.VANGNB10_cI1046c	0.0	968.0	COG2985@1|root,COG3273@1|root,COG2985@2|Bacteria,COG3273@2|Bacteria,1MUVM@1224|Proteobacteria,1RQ47@1236|Gammaproteobacteria,1XSX8@135623|Vibrionales	135623|Vibrionales	P	transport protein	ybjL	-	-	ko:K07085	-	-	-	-	ko00000	2.A.81	-	-	Asp-Al_Ex,TrkA_C
k141_2048_25	345073.VC395_1854	1.34e-263	725.0	COG3007@1|root,COG3007@2|Bacteria,1MWCQ@1224|Proteobacteria,1RPPP@1236|Gammaproteobacteria,1XUMI@135623|Vibrionales	135623|Vibrionales	I	Involved in the final reduction of the elongation cycle of fatty acid synthesis (FAS II). Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP)	fabV	GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004318,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050343,GO:0050662,GO:0051287,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576	1.3.1.44,1.3.1.9	ko:K00209	ko00061,ko00650,ko01100,ko01120,ko01200,ko01212,map00061,map00650,map01100,map01120,map01200,map01212	M00083	R01171,R04429,R04724,R04955,R04958,R04961,R04966,R04969	RC00052,RC00076	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Eno-Rase_FAD_bd,Eno-Rase_NADH_b,Enoyl_reductase
k141_2048_26	1225184.ALXE01000018_gene3805	1.64e-37	132.0	COG1846@1|root,COG1846@2|Bacteria,1RI74@1224|Proteobacteria,1SBD3@1236|Gammaproteobacteria,3W0NQ@53335|Pantoea	1236|Gammaproteobacteria	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
k141_2048_27	634500.EbC_19770	4.98e-100	307.0	COG3180@1|root,COG3180@2|Bacteria,1MUFS@1224|Proteobacteria,1RPMJ@1236|Gammaproteobacteria,3X7BC@551|Erwinia	1236|Gammaproteobacteria	S	Pfam:AmoA	abrB	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K07120	-	-	-	-	ko00000	-	-	-	AbrB
k141_2048_28	1196095.GAPWK_2188	1.28e-47	164.0	COG4565@1|root,COG4565@2|Bacteria,1P6VJ@1224|Proteobacteria,1RPI7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	transcriptional regulatory protein	dpiA	-	-	ko:K02475,ko:K07702	ko02020,map02020	M00486	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	CitT,HTH_IclR,Response_reg
k141_2048_29	717774.Marme_0909	1.96e-149	432.0	COG2828@1|root,COG2828@2|Bacteria,1MXVV@1224|Proteobacteria,1RNE6@1236|Gammaproteobacteria,1XJPB@135619|Oceanospirillales	135619|Oceanospirillales	S	PrpF protein	-	-	-	-	-	-	-	-	-	-	-	-	PrpF
k141_2048_30	572544.Ilyop_0319	6.58e-272	754.0	COG3333@1|root,COG3333@2|Bacteria,3789P@32066|Fusobacteria	32066|Fusobacteria	S	Tripartite tricarboxylate transporter TctA family	-	-	-	-	-	-	-	-	-	-	-	-	TctA
k141_2048_31	572544.Ilyop_0318	5.66e-65	202.0	2EFUW@1|root,339M2@2|Bacteria	2|Bacteria	S	Tripartite tricarboxylate transporter TctB family	-	-	-	ko:K07794	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.80.1	-	-	TctB
k141_2048_32	572544.Ilyop_0317	6.1e-189	530.0	COG3181@1|root,COG3181@2|Bacteria,379KD@32066|Fusobacteria	32066|Fusobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
k141_2048_33	742741.HMPREF9475_00232	7.09e-15	85.9	COG3290@1|root,COG3290@2|Bacteria,1TQJR@1239|Firmicutes,247YE@186801|Clostridia	186801|Clostridia	T	Signal transduction histidine kinase regulating citrate malate metabolism	citS	-	2.7.13.3	ko:K11614,ko:K11691	ko02020,map02020	M00489,M00490	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,PAS,SPOB_a,sCache_3_2
k141_2048_34	1316932.MHH_c20260	0.0	1053.0	COG1049@1|root,COG1049@2|Bacteria,1MVCR@1224|Proteobacteria,1RNMC@1236|Gammaproteobacteria,1Y7C5@135625|Pasteurellales	135625|Pasteurellales	C	Belongs to the aconitase IPM isomerase family	acnB	-	4.2.1.3,4.2.1.99	ko:K01682	ko00020,ko00630,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173	R01324,R01325,R01900,R04425	RC00497,RC00498,RC00618,RC01153	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_2_N,Aconitase_B_N
k141_2048_35	1219065.VPR01S_11_01210	2.95e-217	612.0	COG4452@1|root,COG4452@2|Bacteria,1MVVR@1224|Proteobacteria,1RQRZ@1236|Gammaproteobacteria,1XVM3@135623|Vibrionales	135623|Vibrionales	V	COG4452 Inner membrane protein involved in colicin E2 resistance	creD	-	-	ko:K06143	-	-	-	-	ko00000	-	-	-	CreD
k141_2048_36	1280001.BAOA01000126_gene1135	3.14e-272	753.0	COG0642@1|root,COG2205@2|Bacteria,1N17V@1224|Proteobacteria,1RPVU@1236|Gammaproteobacteria,1XVKV@135623|Vibrionales	135623|Vibrionales	T	COG0642 Signal transduction histidine kinase	creC	-	2.7.13.3	ko:K07641	ko02020,map02020	M00449	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,dCache_3
k141_2048_37	1280001.BAOA01000126_gene1136	1.07e-116	339.0	COG0745@1|root,COG0745@2|Bacteria,1MVCB@1224|Proteobacteria,1S179@1236|Gammaproteobacteria,1XU8X@135623|Vibrionales	135623|Vibrionales	K	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	creB	-	-	ko:K07663	ko02020,map02020	M00449	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
k141_2048_38	1116375.VEJY3_16996	2.85e-154	440.0	COG0697@1|root,COG0697@2|Bacteria,1MY0D@1224|Proteobacteria,1S001@1236|Gammaproteobacteria,1XV8D@135623|Vibrionales	135623|Vibrionales	EG	of the drug metabolite transporter (DMT) superfamily	-	-	-	ko:K15269	-	-	-	-	ko00000,ko02000	2.A.7.3.3	-	-	EamA
k141_2048_39	1116375.VEJY3_16991	2.86e-85	254.0	COG1846@1|root,COG1846@2|Bacteria,1RFUJ@1224|Proteobacteria,1S8JQ@1236|Gammaproteobacteria,1XX84@135623|Vibrionales	135623|Vibrionales	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
k141_711_1	879212.DespoDRAFT_00328	2.03e-97	291.0	COG0294@1|root,COG0294@2|Bacteria,1MUIR@1224|Proteobacteria,42MMY@68525|delta/epsilon subdivisions,2WIXA@28221|Deltaproteobacteria,2MITP@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives	folP	-	2.5.1.15,2.7.6.3	ko:K00796,ko:K13941	ko00790,ko01100,map00790,map01100	M00126,M00840,M00841	R03066,R03067,R03503	RC00002,RC00017,RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
k141_1390_1	930169.B5T_02821	2.34e-21	94.7	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,1XH3T@135619|Oceanospirillales	135619|Oceanospirillales	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k141_1390_2	1161401.ASJA01000006_gene1887	5.5e-52	184.0	COG0845@1|root,COG0845@2|Bacteria,1PEVY@1224|Proteobacteria,2VF2W@28211|Alphaproteobacteria,43WSP@69657|Hyphomonadaceae	28211|Alphaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3
k141_44_2	96561.Dole_2392	4.44e-94	292.0	COG3850@1|root,COG4191@1|root,COG3850@2|Bacteria,COG4191@2|Bacteria,1P0U1@1224|Proteobacteria,42PTP@68525|delta/epsilon subdivisions,2WJ8U@28221|Deltaproteobacteria,2MIQ7@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
k141_2049_2	55601.VANGNB10_cI0839c	2.33e-107	310.0	COG2190@1|root,COG2190@2|Bacteria,1MWIQ@1224|Proteobacteria,1RNE3@1236|Gammaproteobacteria,1XT2S@135623|Vibrionales	135623|Vibrionales	G	COG2190 Phosphotransferase system IIA components	crr	-	-	ko:K02777	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	M00265,M00266,M00268,M00270,M00272,M00303,M00806	R02738,R02780,R04111,R04394,R05132,R08559	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.1.1.1	-	-	PTS_EIIA_1
k141_45_1	485915.Dret_2292	9.71e-205	581.0	COG1785@1|root,COG1785@2|Bacteria,1MXI2@1224|Proteobacteria,42N40@68525|delta/epsilon subdivisions,2WKUV@28221|Deltaproteobacteria,2M83Q@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	Belongs to the alkaline phosphatase family	phoA	-	3.1.3.1	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	M00126	R02135,R04620	RC00017	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	-	-	-	Alk_phosphatase
k141_4108_1	1166016.W5S_4434	1.1e-90	308.0	COG1708@1|root,COG3209@1|root,COG1708@2|Bacteria,COG3209@2|Bacteria,1MVV1@1224|Proteobacteria,1SKYM@1236|Gammaproteobacteria,1MT46@122277|Pectobacterium	1236|Gammaproteobacteria	M	COG3209 Rhs family protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF4150,PAAR_motif,RHS,RHS_repeat,Tox-HNH-EHHH
k141_4108_3	29495.EA26_05690	0.0	985.0	COG3344@1|root,COG3344@2|Bacteria,1MVI1@1224|Proteobacteria,1RQP7@1236|Gammaproteobacteria,1Y0WP@135623|Vibrionales	135623|Vibrionales	L	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	RVT_1
k141_2050_1	313606.M23134_08207	7.88e-32	116.0	COG0262@1|root,COG0262@2|Bacteria,4NQK0@976|Bacteroidetes,47QGE@768503|Cytophagia	976|Bacteroidetes	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
k141_2050_2	864565.HMPREF0379_0292	6.64e-49	177.0	COG0272@1|root,COG0272@2|Bacteria,1TPQ3@1239|Firmicutes,248AX@186801|Clostridia,25R5S@186804|Peptostreptococcaceae	186801|Clostridia	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	-	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
k141_47_1	439235.Dalk_3080	2.97e-72	224.0	COG0131@1|root,COG0131@2|Bacteria,1MWBS@1224|Proteobacteria,42NIV@68525|delta/epsilon subdivisions,2WNA4@28221|Deltaproteobacteria,2MJMY@213118|Desulfobacterales	28221|Deltaproteobacteria	E	PFAM Imidazoleglycerol-phosphate dehydratase	hisB	GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.2.1.19	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03457	RC00932	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPD
k141_1391_1	1249627.D779_3696	3.18e-105	360.0	COG0642@1|root,COG0834@1|root,COG5002@1|root,COG0642@2|Bacteria,COG0834@2|Bacteria,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,1T1JE@1236|Gammaproteobacteria,1X2TY@135613|Chromatiales	135613|Chromatiales	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,PAS_4,Response_reg,SBP_bac_3
k141_712_1	1121403.AUCV01000046_gene1082	1.05e-10	72.4	COG1226@1|root,COG1226@2|Bacteria,1NT9G@1224|Proteobacteria,42TDE@68525|delta/epsilon subdivisions,2WP6G@28221|Deltaproteobacteria,2MKVV@213118|Desulfobacterales	28221|Deltaproteobacteria	P	TrkA-N domain	-	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Castor_Poll_mid,Ion_trans_2,TrkA_N
k141_713_1	1209072.ALBT01000032_gene2173	1.52e-25	108.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	NT	chemotaxis, protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal
k141_365_1	1384057.CD33_01515	7.37e-39	150.0	COG5279@1|root,COG5279@2|Bacteria,1UMNK@1239|Firmicutes,4IV59@91061|Bacilli,3J073@400634|Lysinibacillus	91061|Bacilli	D	Domain of unknown function (DUF5050)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5050,Transglut_core
k141_365_2	1321778.HMPREF1982_04275	1.67e-256	712.0	COG0017@1|root,COG0017@2|Bacteria,1TP38@1239|Firmicutes,2484D@186801|Clostridia,267P5@186813|unclassified Clostridiales	186801|Clostridia	J	tRNA synthetases class II (D, K and N)	asnS	-	6.1.1.22	ko:K01893	ko00970,map00970	M00359,M00360	R03648	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
k141_365_3	1292035.H476_1064	1.56e-79	243.0	COG0778@1|root,COG0778@2|Bacteria,1V2D6@1239|Firmicutes,25B91@186801|Clostridia,25RNX@186804|Peptostreptococcaceae	186801|Clostridia	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
k141_4111_1	1120919.AUBI01000004_gene2006	2.02e-71	229.0	COG1653@1|root,COG1653@2|Bacteria,1MUNZ@1224|Proteobacteria,2TSYG@28211|Alphaproteobacteria,2JR9G@204441|Rhodospirillales	204441|Rhodospirillales	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K10227	ko02010,map02010	M00200	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.5	-	-	SBP_bac_1
k141_1392_1	234831.PSM_B0349	1.42e-39	137.0	COG0582@1|root,COG0582@2|Bacteria,1P1R9@1224|Proteobacteria,1RRV0@1236|Gammaproteobacteria,2Q4E2@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
k141_1392_2	575788.VS_II0084	2.34e-13	74.3	COG4104@1|root,COG4104@2|Bacteria,1RBYJ@1224|Proteobacteria,1S37C@1236|Gammaproteobacteria,1XWGY@135623|Vibrionales	135623|Vibrionales	S	PAAR repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_714_1	1121396.KB893001_gene3968	1.34e-99	296.0	COG0500@1|root,COG2226@2|Bacteria,1MV7N@1224|Proteobacteria,42T49@68525|delta/epsilon subdivisions,2WPYV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
k141_49_2	1121413.JMKT01000014_gene2502	7.3e-40	143.0	COG2063@1|root,COG2063@2|Bacteria,1RDEY@1224|Proteobacteria,42MJW@68525|delta/epsilon subdivisions,2WMYI@28221|Deltaproteobacteria,2MB2X@213115|Desulfovibrionales	28221|Deltaproteobacteria	N	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation	flgH	-	-	ko:K02393	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FlgH
k141_49_3	1304885.AUEY01000102_gene2276	2.62e-135	395.0	COG1706@1|root,COG1706@2|Bacteria,1MVKW@1224|Proteobacteria,42MAU@68525|delta/epsilon subdivisions,2WK22@28221|Deltaproteobacteria,2MI2Y@213118|Desulfobacterales	28221|Deltaproteobacteria	N	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation	flgI	-	-	ko:K02394	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FlgI
k141_366_1	1353537.TP2_09690	1.51e-27	124.0	COG0784@1|root,COG4191@1|root,COG0784@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2TQQ9@28211|Alphaproteobacteria,2XKJM@285107|Thioclava	28211|Alphaproteobacteria	T	PAS fold	cckA	-	2.7.13.3	ko:K13587	ko02020,ko04112,map02020,map04112	M00512	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,PAS,PAS_4,PAS_8,PAS_9,Response_reg
k141_367_1	497965.Cyan7822_2028	3.65e-15	85.1	COG0840@1|root,COG0840@2|Bacteria,1GEWT@1117|Cyanobacteria,3KJ4U@43988|Cyanothece	1117|Cyanobacteria	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_715_1	56780.SYN_00888	2.15e-21	96.7	COG0299@1|root,COG0299@2|Bacteria,1MWN1@1224|Proteobacteria,42R30@68525|delta/epsilon subdivisions,2WJT0@28221|Deltaproteobacteria,2MRWI@213462|Syntrophobacterales	28221|Deltaproteobacteria	F	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate	purN	-	2.1.2.2	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	Formyl_trans_N
k141_2788_3	319224.Sputcn32_1422	2.65e-173	494.0	COG0842@1|root,COG0842@2|Bacteria,1MW5R@1224|Proteobacteria,1RPB4@1236|Gammaproteobacteria,2QARZ@267890|Shewanellaceae	1236|Gammaproteobacteria	V	PFAM ABC-2 type transporter	ybhS	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
k141_2788_4	1237149.C900_03220	5.73e-46	154.0	COG0350@1|root,COG0350@2|Bacteria,4NFYC@976|Bacteroidetes,47RKD@768503|Cytophagia	976|Bacteroidetes	L	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated	ogt	-	2.1.1.63	ko:K00567,ko:K10778	-	-	-	-	ko00000,ko01000,ko03000,ko03400	-	-	-	DNA_binding_1,Methyltransf_1N
k141_2788_5	573413.Spirs_4219	1.18e-79	239.0	COG0432@1|root,COG0432@2|Bacteria	2|Bacteria	S	Uncharacterised protein family UPF0047	-	-	-	-	-	-	-	-	-	-	-	-	UPF0047
k141_2788_7	1051646.VITU9109_18173	1.48e-142	410.0	COG2962@1|root,COG2962@2|Bacteria,1MX5G@1224|Proteobacteria,1RMAC@1236|Gammaproteobacteria,1XSTP@135623|Vibrionales	135623|Vibrionales	S	EamA-like transporter family	rarD	-	-	ko:K05786	-	-	-	-	ko00000,ko02000	2.A.7.7	-	-	EamA
k141_2788_9	1336237.JAEE01000005_gene687	1.04e-51	175.0	COG3021@1|root,COG3021@2|Bacteria,1MVPP@1224|Proteobacteria,1RMBH@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Endonuclease Exonuclease Phosphatase	yafD	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
k141_2788_10	55601.VANGNB10_cI2602c	0.0	1218.0	COG0339@1|root,COG0339@2|Bacteria,1MU1K@1224|Proteobacteria,1RMAH@1236|Gammaproteobacteria,1XTEV@135623|Vibrionales	135623|Vibrionales	E	COG0339 Zn-dependent oligopeptidases	prlC	-	3.4.24.70	ko:K01414	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3
k141_2788_11	29495.EA26_01170	1.17e-184	515.0	COG2961@1|root,COG2961@2|Bacteria,1MWGA@1224|Proteobacteria,1RNI1@1236|Gammaproteobacteria,1XSBI@135623|Vibrionales	135623|Vibrionales	H	Specifically methylates the adenine in position 2030 of 23S rRNA	rlmJ	-	2.1.1.266	ko:K07115	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	RsmJ
k141_2788_12	1348635.BBJY01000024_gene2193	8.41e-300	821.0	COG1249@1|root,COG1249@2|Bacteria,1MU2Z@1224|Proteobacteria,1RMC0@1236|Gammaproteobacteria,1XTC6@135623|Vibrionales	135623|Vibrionales	C	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family	gor	-	1.8.1.7	ko:K00383	ko00480,ko04918,map00480,map04918	-	R00094,R00115	RC00011	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,Pyr_redox_dim
k141_2788_13	1112217.PPL19_09742	5.01e-70	247.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	NT	chemotaxis, protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal
k141_2788_14	82996.sch_10775	1.69e-63	210.0	COG1879@1|root,COG1879@2|Bacteria,1MWGU@1224|Proteobacteria,1RQ56@1236|Gammaproteobacteria,401HV@613|Serratia	1236|Gammaproteobacteria	G	Periplasmic binding protein domain	-	-	-	ko:K10439,ko:K17213	ko02010,ko02030,map02010,map02030	M00212,M00593	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2,3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	Peripla_BP_4
k141_2788_15	675816.VIA_000088	4.29e-86	267.0	2AVT3@1|root,31MKG@2|Bacteria,1QJEW@1224|Proteobacteria,1THE8@1236|Gammaproteobacteria,1XURJ@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	SPOR
k141_1844_2	56780.SYN_03707	2.52e-07	53.1	COG4968@1|root,COG4968@2|Bacteria,1QVB6@1224|Proteobacteria,43BQ3@68525|delta/epsilon subdivisions,2X71E@28221|Deltaproteobacteria	28221|Deltaproteobacteria	U	Prokaryotic N-terminal methylation motif	-	-	-	ko:K02458	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl
k141_4895_1	29495.EA26_08265	9.19e-151	448.0	COG0058@1|root,COG0058@2|Bacteria,1MW4J@1224|Proteobacteria,1RN8P@1236|Gammaproteobacteria,1XSRI@135623|Vibrionales	135623|Vibrionales	G	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties	malP	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	Phosphorylase
k141_4895_2	485913.Krac_5201	3.31e-25	117.0	COG2909@1|root,COG2909@2|Bacteria,2G7Q4@200795|Chloroflexi	200795|Chloroflexi	K	ATP-dependent transcriptional regulator, MalT-like, LuxR family	-	-	-	ko:K03556	-	-	-	-	ko00000,ko03000	-	-	-	GerE
k141_2150_1	1121405.dsmv_1696	2.47e-262	746.0	COG4581@1|root,COG4581@2|Bacteria,1QUPR@1224|Proteobacteria,42NSH@68525|delta/epsilon subdivisions,2WKD7@28221|Deltaproteobacteria,2MHX7@213118|Desulfobacterales	28221|Deltaproteobacteria	L	DEAD DEAH box helicase	-	-	-	-	-	-	-	-	-	-	-	-	DEAD,DSHCT,DUF3516,Helicase_C
k141_2150_2	933262.AXAM01000039_gene1149	5.22e-274	761.0	COG4108@1|root,COG4108@2|Bacteria,1MU7X@1224|Proteobacteria,42MAA@68525|delta/epsilon subdivisions,2WJZC@28221|Deltaproteobacteria,2MHSM@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP	prfC	GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016150,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02837	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,RF3_C
k141_5165_1	1304885.AUEY01000025_gene2765	4.29e-151	447.0	COG0145@1|root,COG0145@2|Bacteria,1MU2Y@1224|Proteobacteria,42P6S@68525|delta/epsilon subdivisions,2WIWC@28221|Deltaproteobacteria,2MI1I@213118|Desulfobacterales	28221|Deltaproteobacteria	EQ	PFAM Hydantoinase oxoprolinase	-	-	-	-	-	-	-	-	-	-	-	-	Hydant_A_N,Hydantoinase_A
k141_5165_2	1304885.AUEY01000025_gene2766	9.81e-224	625.0	COG0123@1|root,COG0123@2|Bacteria,1MU7P@1224|Proteobacteria,42MY3@68525|delta/epsilon subdivisions,2WJEF@28221|Deltaproteobacteria,2MI47@213118|Desulfobacterales	28221|Deltaproteobacteria	BQ	PFAM Histone deacetylase	-	-	-	ko:K04768	-	-	-	-	ko00000	-	-	-	Hist_deacetyl
k141_534_1	1219080.VEZ01S_04_00340	1.01e-21	95.5	COG1287@1|root,COG1287@2|Bacteria,1RCIB@1224|Proteobacteria,1THEW@1236|Gammaproteobacteria,1XV44@135623|Vibrionales	135623|Vibrionales	S	oligosaccharyl transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_534_2	672.VV93_v1c25660	2.55e-214	595.0	COG0057@1|root,COG0057@2|Bacteria,1MU93@1224|Proteobacteria,1RMBM@1236|Gammaproteobacteria,1XUQJ@135623|Vibrionales	135623|Vibrionales	H	Catalyzes the NAD-dependent conversion of D-erythrose 4- phosphate to 4-phosphoerythronate	epd	GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0048001,GO:0055114	1.2.1.72	ko:K03472	ko00750,ko01100,map00750,map01100	M00124	R01825	RC00242	ko00000,ko00001,ko00002,ko01000	-	-	-	Gp_dh_C,Gp_dh_N
k141_534_3	223926.28807610	1.01e-255	704.0	COG0126@1|root,COG0126@2|Bacteria,1MUNU@1224|Proteobacteria,1RMUQ@1236|Gammaproteobacteria,1XT9V@135623|Vibrionales	135623|Vibrionales	F	Belongs to the phosphoglycerate kinase family	pgk	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	2.7.2.3	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01512	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
k141_534_5	945550.VISI1226_02562	1.16e-151	432.0	COG0668@1|root,COG0668@2|Bacteria,1N596@1224|Proteobacteria,1RQZP@1236|Gammaproteobacteria,1XU44@135623|Vibrionales	135623|Vibrionales	M	COG0668 Small-conductance mechanosensitive channel	mscS	-	-	ko:K03442	-	-	-	-	ko00000,ko02000	1.A.23.2	-	-	MS_channel,TM_helix
k141_534_6	617140.AJZE01000084_gene2740	2.02e-71	224.0	COG2968@1|root,COG2968@2|Bacteria,1RH7T@1224|Proteobacteria,1RP7T@1236|Gammaproteobacteria,1XUSG@135623|Vibrionales	135623|Vibrionales	S	Protein of unknown function (DUF541)	-	-	-	ko:K09807	-	-	-	-	ko00000	-	-	-	SIMPL
k141_2789_1	675815.VOA_001645	1.22e-46	160.0	COG4104@1|root,COG4104@2|Bacteria,1RBYJ@1224|Proteobacteria,1S37C@1236|Gammaproteobacteria,1XWGY@135623|Vibrionales	135623|Vibrionales	S	PAAR repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_3176_1	1235798.C817_03670	2.34e-186	523.0	COG2376@1|root,COG2376@2|Bacteria,1TP92@1239|Firmicutes,2488D@186801|Clostridia,27WC1@189330|Dorea	186801|Clostridia	G	Dak1 domain	-	-	2.7.1.121	ko:K05878	ko00561,ko01100,map00561,map01100	-	R01012	RC00015,RC00017	ko00000,ko00001,ko01000	-	-	-	Dak1
k141_3176_2	553973.CLOHYLEM_05929	1.3e-69	219.0	COG1063@1|root,COG1063@2|Bacteria,1TPWP@1239|Firmicutes,248Z5@186801|Clostridia,21ZK2@1506553|Lachnoclostridium	186801|Clostridia	E	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
k141_1155_2	675815.VOA_000367	1.09e-138	395.0	COG2227@1|root,COG2227@2|Bacteria,1MU89@1224|Proteobacteria,1RMV7@1236|Gammaproteobacteria,1XSEV@135623|Vibrionales	135623|Vibrionales	H	O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway	ubiG	GO:0003674,GO:0003824,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008689,GO:0008757,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016741,GO:0032259,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0061542,GO:0071704,GO:1901576,GO:1901661,GO:1901663	2.1.1.222,2.1.1.64	ko:K00568	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04988,R05614,R08769,R08781	RC00003,RC00392,RC01895	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_23
k141_1845_1	1116375.VEJY3_20386	1.96e-138	406.0	COG0508@1|root,COG0508@2|Bacteria,1MUGY@1224|Proteobacteria,1RXCZ@1236|Gammaproteobacteria,1Y0WE@135623|Vibrionales	135623|Vibrionales	C	2-oxoacid dehydrogenases acyltransferase (catalytic domain)	-	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
k141_4897_1	334413.FMG_0978	4.49e-13	70.9	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247PY@186801|Clostridia,22FX5@1570339|Peptoniphilaceae	186801|Clostridia	V	ABC transporter transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
k141_4897_2	493475.GARC_5017	1.24e-29	119.0	COG0834@1|root,COG0834@2|Bacteria,1PT04@1224|Proteobacteria,1RMNK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	ET	Bacterial extracellular solute-binding proteins, family 3	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
k141_1157_1	1163409.UUA_03683	4e-42	157.0	COG1463@1|root,COG3008@1|root,COG1463@2|Bacteria,COG3008@2|Bacteria,1MU1T@1224|Proteobacteria,1RN89@1236|Gammaproteobacteria,1X48N@135614|Xanthomonadales	135614|Xanthomonadales	Q	MlaD protein	-	-	-	ko:K06192	-	-	-	-	ko00000	-	-	-	MlaD
k141_1157_2	391165.GbCGDNIH1_0189	2.28e-19	87.8	COG2995@1|root,COG2995@2|Bacteria,1MWG1@1224|Proteobacteria,2TT3D@28211|Alphaproteobacteria,2JS39@204441|Rhodospirillales	204441|Rhodospirillales	S	Paraquat-inducible protein A	-	-	-	ko:K03808	-	-	-	-	ko00000	-	-	-	PqiA
k141_2790_1	1304885.AUEY01000024_gene2699	1.65e-142	405.0	COG0247@1|root,COG0247@2|Bacteria,1R4ZK@1224|Proteobacteria,42NMT@68525|delta/epsilon subdivisions,2WIQV@28221|Deltaproteobacteria,2MJ6N@213118|Desulfobacterales	28221|Deltaproteobacteria	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_8
k141_2790_2	1121396.KB893089_gene292	1.13e-56	177.0	COG0247@1|root,COG0247@2|Bacteria,1NUW8@1224|Proteobacteria,42PWG@68525|delta/epsilon subdivisions,2WIZA@28221|Deltaproteobacteria,2MIQA@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Cysteine-rich domain	-	-	-	-	-	-	-	-	-	-	-	-	CCG
k141_2790_3	1304885.AUEY01000021_gene3448	1.5e-41	143.0	COG1309@1|root,COG1309@2|Bacteria,1MYFS@1224|Proteobacteria,42T8F@68525|delta/epsilon subdivisions,2WPCH@28221|Deltaproteobacteria,2MK58@213118|Desulfobacterales	28221|Deltaproteobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
k141_3177_1	338963.Pcar_1244	2.68e-125	367.0	COG0133@1|root,COG0133@2|Bacteria,1MUS8@1224|Proteobacteria,42MIA@68525|delta/epsilon subdivisions,2WJJA@28221|Deltaproteobacteria,43U8M@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB	-	4.2.1.20	ko:K01696,ko:K06001	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
k141_3177_2	907348.TresaDRAFT_2487	2.54e-14	70.5	COG4496@1|root,COG4496@2|Bacteria,2J8GD@203691|Spirochaetes	203691|Spirochaetes	S	trp operon repressor	-	-	-	ko:K03720	-	-	-	-	ko00000,ko03000	-	-	-	Trp_repressor
k141_1473_1	243277.VC_A0802	8.67e-209	598.0	COG1368@1|root,COG1368@2|Bacteria,1MVCM@1224|Proteobacteria,1RNJ3@1236|Gammaproteobacteria,1XVBR@135623|Vibrionales	135623|Vibrionales	M	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
k141_1473_2	1283284.AZUK01000001_gene1628	3.35e-151	459.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,1Y57Z@135624|Aeromonadales	1236|Gammaproteobacteria	NT	Cache domain	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal,dCache_1
k141_1846_1	796945.HMPREF1145_1078	6.42e-47	169.0	COG1129@1|root,COG1132@1|root,COG1129@2|Bacteria,COG1132@2|Bacteria,1TQRP@1239|Firmicutes,24YCF@186801|Clostridia,2PT1E@265975|Oribacterium	186801|Clostridia	G	ATPases associated with a variety of cellular activities	-	-	-	ko:K16786,ko:K16787	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ABC_tran
k141_1846_2	999413.HMPREF1094_02175	1.25e-152	457.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,3VQ0W@526524|Erysipelotrichia	526524|Erysipelotrichia	V	ABC transporter transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	ABC_membrane,ABC_tran
k141_1846_3	273121.WS1610	0.000775	43.9	COG4206@1|root,COG4206@2|Bacteria,1QVV2@1224|Proteobacteria,43CBK@68525|delta/epsilon subdivisions,2YTB8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	TonB dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
k141_2151_1	1286632.P278_21350	5.26e-49	191.0	COG0612@1|root,COG0612@2|Bacteria,4NFY0@976|Bacteroidetes,1HYNJ@117743|Flavobacteriia	976|Bacteroidetes	S	Belongs to the peptidase M16 family	pqqL	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
k141_2151_2	1177154.Y5S_00923	9.28e-123	377.0	COG4166@1|root,COG4166@2|Bacteria,1MUVU@1224|Proteobacteria,1RMA1@1236|Gammaproteobacteria,1XITH@135619|Oceanospirillales	135619|Oceanospirillales	E	ABC-type oligopeptide transport system, periplasmic component	-	-	-	ko:K13893	ko02010,map02010	M00349	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.21,3.A.1.5.24	-	-	SBP_bac_5
k141_3853_1	1167006.UWK_00195	2.74e-15	79.3	COG2199@1|root,COG2202@1|root,COG2199@2|Bacteria,COG2202@2|Bacteria	2|Bacteria	T	Pas domain	ytrP	-	2.7.7.65	ko:K13069	-	-	R08057	-	ko00000,ko01000	-	-	-	GAF_2,GAF_3,GGDEF,HAMP,PAS_3
k141_3853_3	1304885.AUEY01000004_gene943	0.0	947.0	COG0441@1|root,COG0441@2|Bacteria,1MUP2@1224|Proteobacteria,42M20@68525|delta/epsilon subdivisions,2WJ2N@28221|Deltaproteobacteria,2MI0Z@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD
k141_3853_4	1304885.AUEY01000004_gene942	6.23e-98	303.0	COG0349@1|root,COG0349@2|Bacteria,1MURV@1224|Proteobacteria,42N0J@68525|delta/epsilon subdivisions,2WJFX@28221|Deltaproteobacteria,2MHNC@213118|Desulfobacterales	28221|Deltaproteobacteria	J	3'-5' exonuclease	rnd	-	3.1.13.5	ko:K03684	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DNA_pol_A_exo1,HRDC
k141_3853_5	177437.HRM2_05330	2.2e-115	334.0	COG0035@1|root,COG0035@2|Bacteria,1MV4N@1224|Proteobacteria,42NNR@68525|delta/epsilon subdivisions,2WK6M@28221|Deltaproteobacteria,2MJ9Q@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate	upp	GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.4.2.9	ko:K00761	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000	-	-	-	UPRTase
k141_4899_1	1304875.JAFZ01000002_gene394	7.75e-27	118.0	COG0845@1|root,COG0845@2|Bacteria,3T9PJ@508458|Synergistetes	508458|Synergistetes	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
k141_4899_2	272559.BF9343_4201	2.57e-73	250.0	COG0841@1|root,COG0841@2|Bacteria,4NDZG@976|Bacteroidetes,2FMG1@200643|Bacteroidia,4AKP8@815|Bacteroidaceae	976|Bacteroidetes	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k141_2791_2	1121396.KB893105_gene1797	5.74e-41	146.0	COG0810@1|root,COG0810@2|Bacteria,1Q1IC@1224|Proteobacteria,437A9@68525|delta/epsilon subdivisions,2X24K@28221|Deltaproteobacteria,2MP57@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Gram-negative bacterial TonB protein C-terminal	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
k141_1474_1	994573.T472_0207740	0.000307	48.9	COG0446@1|root,COG1902@1|root,COG0446@2|Bacteria,COG1902@2|Bacteria,1TPM6@1239|Firmicutes,247V1@186801|Clostridia,36EGZ@31979|Clostridiaceae	186801|Clostridia	C	NADH flavin oxidoreductase NADH oxidase	-	-	1.3.1.31	ko:K10797	ko00360,ko01120,map00360,map01120	-	R02252	RC00669	ko00000,ko00001,ko01000	-	-	-	Oxidored_FMN,Pyr_redox_2
k141_1847_1	29495.EA26_16110	8.43e-230	641.0	COG1263@1|root,COG1264@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,1MY1V@1224|Proteobacteria,1RMYZ@1236|Gammaproteobacteria,1XV6P@135623|Vibrionales	135623|Vibrionales	G	COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific	ptsG	-	2.7.1.199	ko:K02778,ko:K02779	ko00010,ko00520,ko02060,ko05111,map00010,map00520,map02060,map05111	M00265	R02738	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.1.1.1	-	-	PTS_EIIB,PTS_EIIC
k141_3854_1	1536774.H70357_28055	2.44e-10	60.1	COG0451@1|root,COG0451@2|Bacteria,1TQBB@1239|Firmicutes,4HD6J@91061|Bacilli,26UUB@186822|Paenibacillaceae	91061|Bacilli	GM	Polysaccharide biosynthesis protein	capF	-	1.1.1.367	ko:K19068	-	-	-	-	ko00000,ko01000	-	-	-	Epimerase,GPI
k141_3854_2	1177181.T9A_01671	2.61e-137	398.0	COG0381@1|root,COG0381@2|Bacteria,1MWZN@1224|Proteobacteria,1RPNC@1236|Gammaproteobacteria,1XRP8@135619|Oceanospirillales	135619|Oceanospirillales	M	Belongs to the UDP-N-acetylglucosamine 2-epimerase family	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase_2
k141_2152_1	572544.Ilyop_0552	7.88e-32	117.0	COG0225@1|root,COG0225@2|Bacteria,37C62@32066|Fusobacteria	32066|Fusobacteria	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	-	-	1.8.4.11,1.8.4.12	ko:K12267	-	-	-	-	ko00000,ko01000	-	-	-	PMSR
k141_2155_2	198628.Dda3937_04312	8.78e-12	69.3	COG3209@1|root,COG3209@2|Bacteria,1MVV1@1224|Proteobacteria,1SKYM@1236|Gammaproteobacteria,2JEQ6@204037|Dickeya	1236|Gammaproteobacteria	M	TIGRFAM YD repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF4150,PAAR_motif,RHS,RHS_repeat,Tox-HNH-EHHH
k141_2797_2	1461580.CCAS010000115_gene4571	6.62e-09	58.9	COG2801@1|root,COG2801@2|Bacteria,1TQH6@1239|Firmicutes,4HCUT@91061|Bacilli,1ZR3S@1386|Bacillus	91061|Bacilli	L	Mu transposase, C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	HTH_32,Mu-transpos_C,rve
k141_1476_1	1283284.AZUK01000001_gene2308	2.52e-13	63.5	arCOG05874@1|root,2ZJ01@2|Bacteria,1N8VY@1224|Proteobacteria,1SHGZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_4178_2	243277.VC_1096	9.75e-181	508.0	COG0435@1|root,COG0435@2|Bacteria,1MV50@1224|Proteobacteria,1RMTI@1236|Gammaproteobacteria,1XSAM@135623|Vibrionales	135623|Vibrionales	O	Glutathione S-transferase	-	-	1.8.5.7	ko:K07393	-	-	-	-	ko00000,ko01000	-	-	-	GST_C_2,GST_N_2
k141_4178_3	1265503.KB905176_gene4041	9.35e-12	68.2	COG2885@1|root,COG2885@2|Bacteria,1MZTV@1224|Proteobacteria,1S8RG@1236|Gammaproteobacteria,2Q703@267889|Colwelliaceae	1236|Gammaproteobacteria	M	OmpA family	pal	GO:0005575,GO:0005623,GO:0008150,GO:0009279,GO:0009987,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031224,GO:0031230,GO:0031241,GO:0031246,GO:0031975,GO:0032153,GO:0044425,GO:0044462,GO:0044464,GO:0051301,GO:0071944,GO:0098552	-	ko:K03640	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	OmpA
k141_4178_4	1238450.VIBNISOn1_900052	1.55e-67	229.0	COG2304@1|root,COG4961@1|root,COG2304@2|Bacteria,COG4961@2|Bacteria,1R6JY@1224|Proteobacteria,1S1WB@1236|Gammaproteobacteria,1XU5B@135623|Vibrionales	135623|Vibrionales	U	Pilus assembly protein TadG	-	-	-	ko:K12515	-	-	-	-	ko00000,ko02044	-	-	-	Tad
k141_4178_5	575788.VS_0027	1.5e-37	135.0	2BUDU@1|root,32PPT@2|Bacteria,1RJ0W@1224|Proteobacteria,1S68Z@1236|Gammaproteobacteria,1XXDC@135623|Vibrionales	135623|Vibrionales	S	Putative tight adherence pilin protein F	-	-	-	ko:K12514	-	-	-	-	ko00000,ko02044	-	-	-	TadF
k141_4178_6	701176.VIBRN418_08622	1.15e-34	126.0	COG4961@1|root,COG4961@2|Bacteria,1NYV2@1224|Proteobacteria,1SR2B@1236|Gammaproteobacteria,1XVS5@135623|Vibrionales	135623|Vibrionales	U	PFAM TadE family protein	-	-	-	ko:K12513	-	-	-	-	ko00000,ko02044	-	-	-	TadE
k141_4178_7	945550.VISI1226_06099	3.09e-36	136.0	COG5010@1|root,COG5010@2|Bacteria,1R7CW@1224|Proteobacteria,1RR91@1236|Gammaproteobacteria,1XXZJ@135623|Vibrionales	135623|Vibrionales	U	COG5010 Flp pilus assembly protein TadD, contains TPR repeats	-	-	-	ko:K12512	-	-	-	-	ko00000,ko02044	-	-	-	AMIN,SPOR,TPR_16,TPR_19,TPR_8
k141_4178_8	312309.VF_A0225	5.77e-81	254.0	COG2064@1|root,COG2064@2|Bacteria,1MWAZ@1224|Proteobacteria,1S3GC@1236|Gammaproteobacteria,1XUTP@135623|Vibrionales	135623|Vibrionales	NU	COG2064 Flp pilus assembly protein TadC	-	-	-	ko:K12511	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF
k141_4178_9	675817.VDA_000100	1.04e-116	345.0	COG4965@1|root,COG4965@2|Bacteria,1MUXK@1224|Proteobacteria,1RRB5@1236|Gammaproteobacteria,1XVNV@135623|Vibrionales	135623|Vibrionales	U	Flp pilus assembly protein	-	-	-	ko:K12510	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF
k141_4178_10	312309.VF_0516	2.96e-227	635.0	COG4962@1|root,COG4962@2|Bacteria,1R7EN@1224|Proteobacteria,1RP9G@1236|Gammaproteobacteria,1XSF1@135623|Vibrionales	1236|Gammaproteobacteria	U	COG4962 Flp pilus assembly protein, ATPase CpaF	tadA	-	-	ko:K02283	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSE
k141_4178_11	701176.VIBRN418_19949	1.66e-118	358.0	COG0455@1|root,COG0455@2|Bacteria,1NS0S@1224|Proteobacteria,1SK01@1236|Gammaproteobacteria,1XVD9@135623|Vibrionales	135623|Vibrionales	D	COG4963 Flp pilus assembly protein, ATPase CpaE	-	-	-	ko:K02282	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	CBP_BcsQ,CbiA
k141_4178_13	701176.VIBRN418_19959	8.42e-179	513.0	COG4964@1|root,COG4964@2|Bacteria,1MV8G@1224|Proteobacteria,1RQ4U@1236|Gammaproteobacteria,1XSKK@135623|Vibrionales	135623|Vibrionales	U	Belongs to the GSP D family	-	-	-	ko:K02280	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	BON,Secretin,T2SS-T3SS_pil_N
k141_4178_14	1238450.VIBNISOn1_900038	1.35e-47	166.0	COG3745@1|root,COG3745@2|Bacteria,1RM5E@1224|Proteobacteria,1S6ZS@1236|Gammaproteobacteria,1XWH6@135623|Vibrionales	135623|Vibrionales	U	Pilus assembly protein CpaB	-	-	-	ko:K02279	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	RcpC
k141_4178_15	945550.VISI1226_06054	9.13e-11	58.9	COG3847@1|root,COG3847@2|Bacteria,1NAN3@1224|Proteobacteria,1SGJM@1236|Gammaproteobacteria,1XZDT@135623|Vibrionales	135623|Vibrionales	U	Flp/Fap pilin component	-	-	-	ko:K02651	ko04112,map04112	-	-	-	ko00000,ko00001,ko02035,ko02044	-	-	-	Flp_Fap
k141_4178_16	1056512.D515_02276	3.74e-08	52.0	COG3847@1|root,COG3847@2|Bacteria,1NAN3@1224|Proteobacteria,1SGJM@1236|Gammaproteobacteria,1XZDT@135623|Vibrionales	135623|Vibrionales	U	Flp/Fap pilin component	-	-	-	ko:K02651	ko04112,map04112	-	-	-	ko00000,ko00001,ko02035,ko02044	-	-	-	Flp_Fap
k141_4178_17	1348635.BBJY01000004_gene2923	2.23e-115	350.0	COG0642@1|root,COG0642@2|Bacteria,1R54C@1224|Proteobacteria,1RNTM@1236|Gammaproteobacteria,1XUQE@135623|Vibrionales	135623|Vibrionales	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HisKA
k141_4178_18	1348635.BBJY01000004_gene2922	1.42e-109	320.0	COG0745@1|root,COG0745@2|Bacteria,1RA00@1224|Proteobacteria,1S23N@1236|Gammaproteobacteria,1XSB7@135623|Vibrionales	135623|Vibrionales	T	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
k141_4178_19	1219065.VPR01S_19_00720	2.65e-97	294.0	COG0351@1|root,COG0351@2|Bacteria,1MU9J@1224|Proteobacteria,1RNFP@1236|Gammaproteobacteria,1XSEN@135623|Vibrionales	135623|Vibrionales	H	Phosphomethylpyrimidine kinase	thiD	-	2.7.1.49,2.7.4.7	ko:K00941	ko00730,ko01100,map00730,map01100	M00127	R03471,R04509	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Phos_pyr_kin
k141_4178_20	1219065.VPR01S_19_00770	1.75e-103	308.0	COG2145@1|root,COG2145@2|Bacteria,1MVES@1224|Proteobacteria,1RRAE@1236|Gammaproteobacteria,1XSM9@135623|Vibrionales	135623|Vibrionales	H	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)	thiM	-	2.7.1.50	ko:K00878	ko00730,ko01100,map00730,map01100	M00127	R04448	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HK
k141_4178_21	1191299.AJYX01000099_gene847	9.04e-146	427.0	COG0477@1|root,COG2814@2|Bacteria,1R91P@1224|Proteobacteria,1RMVM@1236|Gammaproteobacteria,1XV55@135623|Vibrionales	135623|Vibrionales	EGP	COG0477 Permeases of the major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
k141_4178_23	1219077.VAZ01S_013_00660	2.87e-110	352.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,1XTM0@135623|Vibrionales	135623|Vibrionales	NT	methyl-accepting chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal,dCache_1
k141_4178_24	675814.VIC_004816	2.23e-39	151.0	COG4269@1|root,COG4269@2|Bacteria,1MW5P@1224|Proteobacteria,1RY3G@1236|Gammaproteobacteria,1XSN2@135623|Vibrionales	135623|Vibrionales	S	Bacterial protein of unknown function (DUF898)	-	-	-	-	-	-	-	-	-	-	-	-	DUF898
k141_4178_25	1348635.BBJY01000005_gene3349	7.52e-199	580.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,1THIN@1236|Gammaproteobacteria,1XW5G@135623|Vibrionales	135623|Vibrionales	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,dCache_1
k141_4178_26	1348635.BBJY01000005_gene3350	1.3e-293	829.0	COG3279@1|root,COG5001@1|root,COG3279@2|Bacteria,COG5001@2|Bacteria,1MUNI@1224|Proteobacteria,1RRUX@1236|Gammaproteobacteria,1XSJK@135623|Vibrionales	135623|Vibrionales	T	Domain of unknown function (DUF3369)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3369,EAL,GGDEF,Response_reg
k141_4178_27	1051646.VITU9109_24265	1.78e-163	462.0	COG3623@1|root,COG3623@2|Bacteria,1MWTD@1224|Proteobacteria,1RPT6@1236|Gammaproteobacteria,1XVJF@135623|Vibrionales	135623|Vibrionales	G	3-epimerase	sgbU	-	5.1.3.22	ko:K03079	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	M00550	R03244	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	AP_endonuc_2
k141_3225_24	595494.Tola_0996	4.38e-160	457.0	COG0604@1|root,COG0604@2|Bacteria,1MV3W@1224|Proteobacteria,1RMHG@1236|Gammaproteobacteria,1Y50T@135624|Aeromonadales	135624|Aeromonadales	C	Zinc-binding dehydrogenase	-	-	-	ko:K19745	ko00640,ko01100,map00640,map01100	-	R00919	RC00095	ko00000,ko00001,ko01000	-	-	-	ADH_zinc_N
k141_3225_25	595494.Tola_0997	1.17e-86	261.0	COG1309@1|root,COG1309@2|Bacteria,1RA4T@1224|Proteobacteria,1RNQH@1236|Gammaproteobacteria,1Y699@135624|Aeromonadales	135624|Aeromonadales	K	Bacterial transcriptional repressor C-terminal	-	-	-	ko:K16137	-	-	-	-	ko00000,ko03000	-	-	-	TetR_C_13,TetR_N
k141_3225_26	1117318.PRUB_22646	5.43e-203	588.0	COG4412@1|root,COG4412@2|Bacteria,1MWWV@1224|Proteobacteria,1RZM5@1236|Gammaproteobacteria,2Q02Y@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	M	COG1404 Subtilisin-like serine proteases	-	-	-	ko:K09607	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M6
k141_1517_1	1283284.AZUK01000001_gene1432	1.4e-133	400.0	COG0715@1|root,COG2199@1|root,COG0715@2|Bacteria,COG3706@2|Bacteria,1QUXS@1224|Proteobacteria,1T258@1236|Gammaproteobacteria,1Y6PW@135624|Aeromonadales	135624|Aeromonadales	PT	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,NMT1,PAS_3
k141_1517_2	870967.VIS19158_07777	5.33e-74	232.0	COG3335@1|root,COG3415@1|root,COG3335@2|Bacteria,COG3415@2|Bacteria,1Q7PK@1224|Proteobacteria,1RSF0@1236|Gammaproteobacteria,1Y326@135623|Vibrionales	135623|Vibrionales	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,HTH_29,HTH_33
k141_4629_1	283942.IL1683	7.98e-185	559.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,2QFP8@267893|Idiomarinaceae	1236|Gammaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran,DUF805
k141_3582_1	485915.Dret_1483	1.67e-223	627.0	COG1115@1|root,COG1115@2|Bacteria,1MUI3@1224|Proteobacteria,42MG1@68525|delta/epsilon subdivisions,2WKHE@28221|Deltaproteobacteria,2M86Y@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	amino acid carrier protein	-	-	-	ko:K03310	-	-	-	-	ko00000	2.A.25	-	-	Na_Ala_symp
k141_3920_1	1123274.KB899415_gene2464	8.65e-31	116.0	COG0524@1|root,COG0524@2|Bacteria,2JA75@203691|Spirochaetes	203691|Spirochaetes	G	COGs COG0524 Sugar kinase ribokinase family	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
k141_3920_2	633697.EubceDRAFT1_1754	6.06e-18	84.3	COG1283@1|root,COG1283@2|Bacteria,1TP4K@1239|Firmicutes,247KT@186801|Clostridia,25V23@186806|Eubacteriaceae	186801|Clostridia	P	Na Pi-cotransporter II-like protein	-	-	-	ko:K03324	-	-	-	-	ko00000,ko02000	2.A.58.2	-	-	Na_Pi_cotrans,PhoU
k141_268_2	391009.Tmel_0261	1.67e-11	69.3	COG2199@1|root,COG3706@2|Bacteria,2GCIY@200918|Thermotogae	200918|Thermotogae	T	response regulator	-	-	2.7.7.65	ko:K02488	ko02020,ko04112,map02020,map04112	M00511	R08057	-	ko00000,ko00001,ko00002,ko01000,ko02022	-	-	-	GGDEF,Response_reg
k141_268_3	1082705.JIBP01000003_gene2528	9.24e-35	125.0	COG0394@1|root,COG0394@2|Bacteria,1N0DZ@1224|Proteobacteria,1S92S@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Belongs to the low molecular weight phosphotyrosine protein phosphatase family	wzb	-	3.1.3.48	ko:K01104,ko:K20945	ko05111,map05111	-	-	-	ko00000,ko00001,ko01000	-	-	-	LMWPc
k141_268_4	1120970.AUBZ01000003_gene164	4.01e-81	254.0	COG3267@1|root,COG3267@2|Bacteria,1MU3G@1224|Proteobacteria,1RMI0@1236|Gammaproteobacteria,465NU@72275|Alteromonadaceae	1236|Gammaproteobacteria	U	general secretion pathway protein	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22
k141_3921_1	765913.ThidrDRAFT_2517	6.78e-88	286.0	COG1262@1|root,COG1262@2|Bacteria,1QT7U@1224|Proteobacteria,1RWY0@1236|Gammaproteobacteria,1X0ZN@135613|Chromatiales	135613|Chromatiales	S	CDS with the same product name	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
k141_4944_1	349965.yinte0001_27260	1.54e-291	800.0	COG1486@1|root,COG1486@2|Bacteria,1NI6G@1224|Proteobacteria,1RN45@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	Catalyses the hydrolysis of terminal non-reducing alpha-D-galactose residues in alpha-D-galactosides	melA	GO:0000166,GO:0003674,GO:0003824,GO:0004553,GO:0004557,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005984,GO:0005994,GO:0005995,GO:0008150,GO:0008152,GO:0009056,GO:0009311,GO:0009313,GO:0009987,GO:0015925,GO:0016052,GO:0016787,GO:0016798,GO:0030145,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044275,GO:0044424,GO:0044444,GO:0044464,GO:0046352,GO:0046872,GO:0046914,GO:0048037,GO:0050662,GO:0051287,GO:0070403,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901575	3.2.1.22	ko:K07406	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	-	R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091	RC00049,RC00059,RC00451	ko00000,ko00001,ko01000	-	-	iECH74115_1262.ECH74115_5633,iECSP_1301.ECSP_5218,iECs_1301.ECs5101	Glyco_hydro_4,Glyco_hydro_4C
k141_4944_2	1524467.IV04_03915	2.17e-251	700.0	COG2211@1|root,COG2211@2|Bacteria,1MVUM@1224|Proteobacteria,1RP5J@1236|Gammaproteobacteria,3ZZWT@613|Serratia	1236|Gammaproteobacteria	G	transporter	melB	GO:0003674,GO:0005215,GO:0005402,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008150,GO:0008324,GO:0008643,GO:0015075,GO:0015077,GO:0015081,GO:0015144,GO:0015154,GO:0015156,GO:0015157,GO:0015291,GO:0015293,GO:0015294,GO:0015318,GO:0015370,GO:0015487,GO:0015592,GO:0015672,GO:0015765,GO:0015766,GO:0015769,GO:0015772,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0031226,GO:0034219,GO:0034220,GO:0035725,GO:0043887,GO:0044425,GO:0044459,GO:0044464,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:1901264,GO:1901505,GO:1901656	-	ko:K03292,ko:K11104	-	-	-	-	ko00000,ko02000	2.A.2,2.A.2.1	-	iBWG_1329.BWG_3833,iECDH10B_1368.ECDH10B_4312,iECDH1ME8569_1439.ECDH1ME8569_3979,iEKO11_1354.EKO11_4199,iEcDH1_1363.EcDH1_3872	MFS_2
k141_4944_3	573.JG24_23105	8.54e-17	82.8	COG1802@1|root,COG1802@2|Bacteria	2|Bacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
k141_4944_4	1028307.EAE_04580	8.33e-63	201.0	COG1802@1|root,COG1802@2|Bacteria,1PVSJ@1224|Proteobacteria,1S0ZK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	FCD	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
k141_4944_5	696748.ASU2_10905	1.6e-14	70.5	COG1838@1|root,COG1838@2|Bacteria,1MVNG@1224|Proteobacteria,1RMT4@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	)-tartrate dehydratase	ttdB	GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0050896	4.2.1.32	ko:K03780	ko00630,map00630	-	R00339	RC01382	ko00000,ko00001,ko01000	-	-	iSBO_1134.SBO_2920	Fumerase_C
k141_556_1	177437.HRM2_p00250	3.23e-61	218.0	COG0784@1|root,COG2202@1|root,COG4191@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MC4@68525|delta/epsilon subdivisions,2WIZU@28221|Deltaproteobacteria,2MHWA@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	ABC_sub_bind,HATPase_c,HisKA,PAS,PAS_3,PAS_8,PAS_9,Response_reg
k141_3583_1	1304885.AUEY01000067_gene1315	1.63e-89	275.0	COG1721@1|root,COG1721@2|Bacteria,1Q7RR@1224|Proteobacteria,42PJB@68525|delta/epsilon subdivisions,2WK1X@28221|Deltaproteobacteria,2MJBE@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
k141_3583_2	1304885.AUEY01000067_gene1316	1.44e-145	421.0	COG0714@1|root,COG0714@2|Bacteria,1MUFN@1224|Proteobacteria,42NCX@68525|delta/epsilon subdivisions,2WJUZ@28221|Deltaproteobacteria,2MHQ8@213118|Desulfobacterales	28221|Deltaproteobacteria	S	PFAM ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
k141_568_1	156578.ATW7_01455	5.79e-76	239.0	COG0583@1|root,COG0583@2|Bacteria,1N87S@1224|Proteobacteria,1RRED@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
k141_1535_2	1123274.KB899409_gene429	5.22e-32	116.0	COG1664@1|root,COG1664@2|Bacteria,2J861@203691|Spirochaetes	203691|Spirochaetes	M	Integral membrane protein CcmA involved in cell shape determination	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
k141_795_1	305900.GV64_07400	5.94e-173	519.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,1XHXU@135619|Oceanospirillales	135619|Oceanospirillales	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k141_795_2	506534.Rhein_1545	1.44e-19	96.7	COG0845@1|root,COG0845@2|Bacteria,1R4JA@1224|Proteobacteria,1RPS5@1236|Gammaproteobacteria,1WYI5@135613|Chromatiales	135613|Chromatiales	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
k141_3603_1	1123355.JHYO01000026_gene227	5.27e-157	508.0	COG0642@1|root,COG5002@1|root,COG0642@2|Bacteria,COG2205@2|Bacteria,COG5002@2|Bacteria,1NRP8@1224|Proteobacteria,2TWN3@28211|Alphaproteobacteria,36XKK@31993|Methylocystaceae	28211|Alphaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,Response_reg
k141_3603_2	1205753.A989_18603	1.8e-111	330.0	COG3437@1|root,COG3437@2|Bacteria,1MUB8@1224|Proteobacteria,1RPH3@1236|Gammaproteobacteria,1X52C@135614|Xanthomonadales	135614|Xanthomonadales	T	Response regulator containing a CheY-like receiver domain and an HD-GYP domain	-	-	-	ko:K07814	-	-	-	-	ko00000,ko02022	-	-	-	HD,HD_5,Response_reg
k141_1919_1	717231.Flexsi_1202	1.28e-122	367.0	COG1283@1|root,COG1283@2|Bacteria,2GEY7@200930|Deferribacteres	200930|Deferribacteres	P	Na+/Pi-cotransporter	-	-	-	ko:K03324	-	-	-	-	ko00000,ko02000	2.A.58.2	-	-	Na_Pi_cotrans,PhoU
k141_1919_2	469617.FUAG_00408	1.45e-11	72.8	COG1283@1|root,COG1283@2|Bacteria,378CQ@32066|Fusobacteria	32066|Fusobacteria	P	Na Pi-cotransporter II-like protein	-	-	-	ko:K03324	-	-	-	-	ko00000,ko02000	2.A.58.2	-	-	Na_Pi_cotrans,PhoU
k141_2509_2	1499967.BAYZ01000061_gene5979	2.75e-35	139.0	COG5001@1|root,COG5001@2|Bacteria,2NP1A@2323|unclassified Bacteria	2|Bacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,MASE1,PAS,PAS_3,PAS_4,PAS_9,Response_reg
k141_2509_3	96561.Dole_0173	9.17e-140	402.0	COG1032@1|root,COG1032@2|Bacteria,1P9J0@1224|Proteobacteria,42MWG@68525|delta/epsilon subdivisions,2WIV5@28221|Deltaproteobacteria,2MI1A@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM Radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
k141_2509_4	697282.Mettu_2072	1.2e-72	237.0	COG1322@1|root,COG1322@2|Bacteria,1MWHV@1224|Proteobacteria,1RMB8@1236|Gammaproteobacteria,1XE87@135618|Methylococcales	135618|Methylococcales	S	RmuC family	-	-	-	ko:K09760	-	-	-	-	ko00000	-	-	-	RmuC
k141_2231_3	1379698.RBG1_1C00001G0745	1.32e-60	217.0	COG1574@1|root,COG1574@2|Bacteria,2NNTF@2323|unclassified Bacteria	2|Bacteria	S	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
k141_2231_4	515635.Dtur_0535	5.48e-36	136.0	COG1237@1|root,COG1237@2|Bacteria	2|Bacteria	S	Metallo-beta-lactamase superfamily	-	-	2.5.1.105	ko:K06897	ko00790,map00790	-	R10339	RC00121	ko00000,ko00001,ko01000	-	-	-	Lactamase_B
k141_3934_1	675815.VOA_002482	9.45e-172	488.0	COG1344@1|root,COG1344@2|Bacteria,1MV1N@1224|Proteobacteria,1RN0Y@1236|Gammaproteobacteria,1XSDK@135623|Vibrionales	135623|Vibrionales	N	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella	flaB	GO:0005575,GO:0005576,GO:0005623,GO:0009288,GO:0042995,GO:0043226,GO:0043228,GO:0044464	-	ko:K02406	ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flagellin_C,Flagellin_IN,Flagellin_N
k141_1922_1	929558.SMGD1_0311	7.47e-40	153.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,42M0W@68525|delta/epsilon subdivisions,2YMHP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	signal transduction protein containing a membrane domain an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,EAL,GGDEF,PAS_4
k141_2232_1	1304885.AUEY01000003_gene493	2.09e-126	370.0	COG1294@1|root,COG1294@2|Bacteria,1MURP@1224|Proteobacteria,42NHN@68525|delta/epsilon subdivisions,2WJ4S@28221|Deltaproteobacteria,2MHWJ@213118|Desulfobacterales	28221|Deltaproteobacteria	C	TIGRFAM cytochrome d ubiquinol oxidase, subunit II	cydB	-	1.10.3.14	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	Cyt_bd_oxida_II
k141_4240_1	1238450.VIBNISOn1_1670021	6.02e-47	167.0	COG1874@1|root,COG1874@2|Bacteria,1MUVR@1224|Proteobacteria,1RPW9@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	beta-galactosidase	bglY	-	3.2.1.23	ko:K12308	ko00052,map00052	-	R01105	RC00452	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_42,Glyco_hydro_42C,Glyco_hydro_42M
k141_4240_2	1238450.VIBNISOn1_1670020	1.46e-130	385.0	COG4580@1|root,COG4580@2|Bacteria,1MX77@1224|Proteobacteria,1RPMF@1236|Gammaproteobacteria,1XU0M@135623|Vibrionales	135623|Vibrionales	M	Involved in the transport of maltose and maltodextrins	lamB	GO:0003674,GO:0005215,GO:0005363,GO:0006810,GO:0008150,GO:0008643,GO:0015144,GO:0015154,GO:0015157,GO:0015267,GO:0015288,GO:0015481,GO:0015766,GO:0015768,GO:0015772,GO:0022803,GO:0022829,GO:0022857,GO:0034219,GO:0051179,GO:0051234,GO:0055085,GO:0071702	-	ko:K02024	-	-	-	-	ko00000,ko02000	1.B.3.1.1	-	-	LamB
k141_1245_1	1540257.JQMW01000013_gene1163	1.54e-209	594.0	COG1115@1|root,COG1115@2|Bacteria,1TNZP@1239|Firmicutes,247S6@186801|Clostridia,36F13@31979|Clostridiaceae	186801|Clostridia	E	amino acid carrier protein	glnT	-	-	ko:K03310	-	-	-	-	ko00000	2.A.25	-	-	Na_Ala_symp
k141_1245_2	1511.CLOST_1823	2.93e-140	405.0	COG2066@1|root,COG2066@2|Bacteria,1TP64@1239|Firmicutes,2491K@186801|Clostridia,25S53@186804|Peptostreptococcaceae	186801|Clostridia	E	Glutaminase	glsA	-	3.5.1.2	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	-	R00256,R01579	RC00010,RC02798	ko00000,ko00001,ko01000	-	-	-	Glutaminase
k141_1245_3	1487921.DP68_16615	6.41e-189	541.0	COG2204@1|root,COG2204@2|Bacteria,1VSKG@1239|Firmicutes,24ZP4@186801|Clostridia,36EVK@31979|Clostridiaceae	186801|Clostridia	T	Two component, sigma54 specific, transcriptional regulator, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
k141_1245_4	1230342.CTM_11790	1.89e-106	334.0	COG5000@1|root,COG5000@2|Bacteria,1V3IT@1239|Firmicutes,249GI@186801|Clostridia,36FPA@31979|Clostridiaceae	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
k141_1245_5	1487921.DP68_16625	1.29e-63	219.0	COG0840@1|root,COG0840@2|Bacteria,1US07@1239|Firmicutes,24Y5V@186801|Clostridia,36RB8@31979|Clostridiaceae	186801|Clostridia	NT	Cache domain	-	-	-	-	-	-	-	-	-	-	-	-	dCache_1
k141_1245_6	536232.CLM_0798	4.09e-115	341.0	COG2367@1|root,COG2367@2|Bacteria,1TQFB@1239|Firmicutes,249R7@186801|Clostridia,36F9K@31979|Clostridiaceae	186801|Clostridia	V	Beta-lactamase	-	-	3.5.2.6	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	M00627,M00628	R06363	RC01499	ko00000,ko00001,ko00002,ko01000,ko01504	-	-	-	Beta-lactamase2
k141_1245_7	997346.HMPREF9374_3946	1.27e-106	341.0	COG2602@1|root,COG4219@1|root,COG2602@2|Bacteria,COG4219@2|Bacteria,1TP3Z@1239|Firmicutes,4HB9X@91061|Bacilli	91061|Bacilli	KT	signal transduction N-terminal membrane component	mecR1	-	-	ko:K02172,ko:K02547	ko01501,map01501	M00625,M00627	-	-	ko00000,ko00001,ko00002,ko01002,ko01504	-	-	-	Peptidase_M56,Transpeptidase
k141_1245_8	748727.CLJU_c13470	1.23e-46	154.0	COG3682@1|root,COG3682@2|Bacteria,1V7EY@1239|Firmicutes,24N11@186801|Clostridia,36J44@31979|Clostridiaceae	186801|Clostridia	K	Penicillinase repressor	blaI	-	-	ko:K02171	ko01501,map01501	M00627	-	-	ko00000,ko00001,ko00002,ko01504,ko03000	-	-	-	Penicillinase_R
k141_1245_9	1121342.AUCO01000015_gene2647	1.08e-140	439.0	COG3973@1|root,COG3973@2|Bacteria,1TP39@1239|Firmicutes,249IG@186801|Clostridia,36E3M@31979|Clostridiaceae	186801|Clostridia	L	DNA helicase	-	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AAA_19,UvrD-helicase,UvrD_C,UvrD_C_2
k141_1245_10	536227.CcarbDRAFT_2536	1.87e-93	279.0	COG1139@1|root,COG1139@2|Bacteria,1TP90@1239|Firmicutes,249B6@186801|Clostridia,36FNS@31979|Clostridiaceae	186801|Clostridia	C	LUD domain	-	-	-	-	-	-	-	-	-	-	-	-	LUD_dom
k141_1245_11	1121324.CLIT_24c00180	0.0	991.0	COG0143@1|root,COG0143@2|Bacteria,1TPA1@1239|Firmicutes,248AU@186801|Clostridia,25QC3@186804|Peptostreptococcaceae	186801|Clostridia	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	-	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g,tRNA_bind
k141_1245_13	1292035.H476_3235	4.67e-244	682.0	COG1488@1|root,COG1488@2|Bacteria,1TPDW@1239|Firmicutes,247NY@186801|Clostridia,25QNQ@186804|Peptostreptococcaceae	186801|Clostridia	H	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP	pncB	-	6.3.4.21	ko:K00763	ko00760,ko01100,map00760,map01100	-	R01724	RC00033	ko00000,ko00001,ko01000	-	-	-	NAPRTase,QRPTase_C,QRPTase_N
k141_1245_14	1280692.AUJL01000019_gene924	5.91e-41	136.0	COG2002@1|root,COG2002@2|Bacteria,1VA3H@1239|Firmicutes,24MN7@186801|Clostridia,36KGI@31979|Clostridiaceae	186801|Clostridia	K	AbrB family	NPD5_2057	-	-	ko:K06284	-	-	-	-	ko00000,ko03000	-	-	-	MazE_antitoxin
k141_1245_15	866895.HBHAL_1052	2.7e-87	269.0	COG0313@1|root,COG0313@2|Bacteria,1TP6U@1239|Firmicutes,4HAH8@91061|Bacilli,3NE9G@45667|Halobacillus	91061|Bacilli	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA	rsmI	GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
k141_1245_16	1151292.QEW_4174	2.26e-113	332.0	COG4123@1|root,COG4123@2|Bacteria,1TQ25@1239|Firmicutes,249UH@186801|Clostridia,25QWN@186804|Peptostreptococcaceae	186801|Clostridia	S	Methyltransferase domain	yfiC	-	2.1.1.223	ko:K15460	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	MTS,Methyltransf_31
k141_1245_18	1121324.CLIT_24c00280	7.91e-251	701.0	COG0733@1|root,COG0733@2|Bacteria,1TP6B@1239|Firmicutes,2485D@186801|Clostridia,25S4A@186804|Peptostreptococcaceae	186801|Clostridia	S	Sodium neurotransmitter symporter family protein	-	-	-	ko:K03308	-	-	-	-	ko00000	2.A.22.4,2.A.22.5	-	-	SNF
k141_1245_20	1121324.CLIT_24c00290	7.71e-138	402.0	COG1774@1|root,COG1774@2|Bacteria,1TP1V@1239|Firmicutes,247Q6@186801|Clostridia,25QP1@186804|Peptostreptococcaceae	186801|Clostridia	S	PSP1 C-terminal domain protein	yaaT	-	-	-	-	-	-	-	-	-	-	-	PSP1
k141_1245_21	1408324.JNJK01000019_gene2533	1.26e-44	162.0	COG2812@1|root,COG2812@2|Bacteria,1VCQC@1239|Firmicutes,248U4@186801|Clostridia,27IHW@186928|unclassified Lachnospiraceae	186801|Clostridia	L	DNA polymerase III, delta subunit	holB	-	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNApol3-delta_C
k141_1245_22	1391646.AVSU01000045_gene1464	1.12e-111	326.0	COG0125@1|root,COG0125@2|Bacteria,1V2D5@1239|Firmicutes,25J57@186801|Clostridia,25QYY@186804|Peptostreptococcaceae	186801|Clostridia	F	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	tmk	-	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylate_kin
k141_1245_24	445335.CBN_2141	1.1e-59	205.0	COG1403@1|root,COG1403@2|Bacteria,1VFQ8@1239|Firmicutes,25AX9@186801|Clostridia,36MCQ@31979|Clostridiaceae	186801|Clostridia	V	HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_1245_25	485916.Dtox_1424	2.98e-57	214.0	COG3950@1|root,COG3950@2|Bacteria,1VHTQ@1239|Firmicutes,24R73@186801|Clostridia	186801|Clostridia	L	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	-	-	-	-	-	-	-	-	-	AAA_21
k141_1245_27	1286171.EAL2_808p03650	3.26e-115	336.0	COG0450@1|root,COG0450@2|Bacteria,1TQU7@1239|Firmicutes,24A31@186801|Clostridia,25W5Y@186806|Eubacteriaceae	186801|Clostridia	O	C-terminal domain of 1-Cys peroxiredoxin	ahpC	-	1.11.1.15	ko:K03386	ko04214,map04214	-	-	-	ko00000,ko00001,ko01000,ko04147	-	-	-	1-cysPrx_C,AhpC-TSA
k141_1245_28	562743.JH976443_gene3410	6.63e-61	190.0	COG0103@1|root,COG0103@2|Bacteria,1V3MQ@1239|Firmicutes,4HH3B@91061|Bacilli	91061|Bacilli	J	Belongs to the universal ribosomal protein uS9 family	rpsI	GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
k141_1245_29	1286171.EAL2_c01920	3.99e-70	214.0	COG0102@1|root,COG0102@2|Bacteria,1V3HX@1239|Firmicutes,24HD9@186801|Clostridia,25WEH@186806|Eubacteriaceae	186801|Clostridia	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rplM	-	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
k141_1245_30	411489.CLOL250_02274	1.86e-67	215.0	COG0101@1|root,COG0101@2|Bacteria,1TQUY@1239|Firmicutes,248W2@186801|Clostridia,36DP0@31979|Clostridiaceae	186801|Clostridia	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	-	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
k141_1245_31	1511.CLOST_2164	1.76e-122	357.0	COG0619@1|root,COG0619@2|Bacteria,1TQ0E@1239|Firmicutes,248AB@186801|Clostridia,25QTH@186804|Peptostreptococcaceae	186801|Clostridia	P	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates	ecfT	-	-	ko:K16785	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	CbiQ
k141_1245_32	1262449.CP6013_0878	1.4e-124	363.0	COG1122@1|root,COG1122@2|Bacteria,1TPH8@1239|Firmicutes,248A2@186801|Clostridia,36F0E@31979|Clostridiaceae	186801|Clostridia	P	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates	ecfA	-	-	ko:K16786,ko:K16787	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ABC_tran
k141_1245_33	1035196.HMPREF9998_00697	2.58e-139	401.0	COG1122@1|root,COG1122@2|Bacteria,1TPH8@1239|Firmicutes,248A2@186801|Clostridia,25R7X@186804|Peptostreptococcaceae	186801|Clostridia	P	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates	ecfA	-	-	ko:K16786,ko:K16787	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ABC_tran
k141_1245_34	445973.CLOBAR_00122	1.78e-57	180.0	COG0203@1|root,COG0203@2|Bacteria,1V6JQ@1239|Firmicutes,24J9T@186801|Clostridia,25RDK@186804|Peptostreptococcaceae	186801|Clostridia	J	50S ribosomal protein L17	rplQ	-	-	ko:K02879	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L17
k141_1245_35	500633.CLOHIR_01604	3.96e-180	506.0	COG0202@1|root,COG0202@2|Bacteria,1TPR8@1239|Firmicutes,248DS@186801|Clostridia,25QH3@186804|Peptostreptococcaceae	186801|Clostridia	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	-	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
k141_1245_36	1286171.EAL2_c01850	6.58e-114	330.0	COG0522@1|root,COG0522@2|Bacteria,1TR0J@1239|Firmicutes,248Y5@186801|Clostridia,25VYW@186806|Eubacteriaceae	186801|Clostridia	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	-	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
k141_1245_37	796940.HMPREF9628_00463	1.52e-74	224.0	COG0100@1|root,COG0100@2|Bacteria,1V3IK@1239|Firmicutes,24HIK@186801|Clostridia,25R98@186804|Peptostreptococcaceae	186801|Clostridia	J	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome	rpsK	-	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
k141_1245_38	1035196.HMPREF9998_00689	1.1e-62	194.0	COG0099@1|root,COG0099@2|Bacteria,1V3JH@1239|Firmicutes,24HCT@186801|Clostridia,25T88@186804|Peptostreptococcaceae	186801|Clostridia	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	rpsM	-	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
k141_4336_6	796620.VIBC2010_19730	6.6e-70	221.0	COG2197@1|root,COG2197@2|Bacteria,1RFQS@1224|Proteobacteria,1S3NH@1236|Gammaproteobacteria	1236|Gammaproteobacteria	KT	SnoaL-like polyketide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GerE,SnoaL
k141_4336_7	626887.J057_16520	4.12e-58	184.0	COG1764@1|root,COG1764@2|Bacteria,1RD1A@1224|Proteobacteria,1S3UA@1236|Gammaproteobacteria,467CA@72275|Alteromonadaceae	1236|Gammaproteobacteria	O	redox protein, regulator of disulfide bond formation	ohr	-	-	-	-	-	-	-	-	-	-	-	OsmC
k141_4336_8	264198.Reut_A0026	3.28e-107	315.0	COG0693@1|root,COG0693@2|Bacteria,1MVTT@1224|Proteobacteria,2VKUH@28216|Betaproteobacteria,1K23D@119060|Burkholderiaceae	28216|Betaproteobacteria	S	PFAM ThiJ PfpI domain protein	nonF	-	-	-	-	-	-	-	-	-	-	-	DJ-1_PfpI
k141_4336_9	312309.VF_A0764	7.4e-32	117.0	COG3631@1|root,COG3631@2|Bacteria,1MZS5@1224|Proteobacteria,1S8VN@1236|Gammaproteobacteria,1XXE4@135623|Vibrionales	135623|Vibrionales	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
k141_4336_10	1280001.BAOA01000027_gene4810	4.42e-103	305.0	COG0300@1|root,COG0300@2|Bacteria,1N9YK@1224|Proteobacteria,1T1TA@1236|Gammaproteobacteria,1Y32C@135623|Vibrionales	135623|Vibrionales	S	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
k141_4336_11	674977.VMC_32600	9.69e-214	601.0	COG2907@1|root,COG2907@2|Bacteria,1MV4Z@1224|Proteobacteria,1RP4P@1236|Gammaproteobacteria,1XSW6@135623|Vibrionales	135623|Vibrionales	S	NAD FAD-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
k141_4336_12	1517681.HW45_23615	2.58e-126	366.0	COG3496@1|root,COG3496@2|Bacteria,1RC56@1224|Proteobacteria,1RRT8@1236|Gammaproteobacteria,1XW4E@135623|Vibrionales	135623|Vibrionales	S	Protein of unknown function (DUF1365)	-	-	-	ko:K09701	-	-	-	-	ko00000	-	-	-	DUF1365
k141_4336_13	29495.EA26_15860	1.26e-180	516.0	COG2230@1|root,COG2230@2|Bacteria,1MX3U@1224|Proteobacteria,1RNID@1236|Gammaproteobacteria,1XSW4@135623|Vibrionales	135623|Vibrionales	M	COG2230 Cyclopropane fatty acid synthase and related methyltransferases	cfa	-	2.1.1.79	ko:K00574	-	-	-	-	ko00000,ko01000	-	-	-	CMAS
k141_4336_14	223926.28806111	3.22e-31	117.0	2DM7V@1|root,323W3@2|Bacteria,1NPYM@1224|Proteobacteria,1SJ13@1236|Gammaproteobacteria,1XY2N@135623|Vibrionales	135623|Vibrionales	S	Protein of unknown function (DUF2878)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2878
k141_4336_15	1219076.N646_0176	1.34e-61	196.0	COG3572@1|root,COG3572@2|Bacteria,1RKWZ@1224|Proteobacteria,1S89R@1236|Gammaproteobacteria,1XXU8@135623|Vibrionales	135623|Vibrionales	H	ergothioneine biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	Chalcone_3
k141_4336_20	675814.VIC_005010	8.11e-217	605.0	COG0626@1|root,COG0626@2|Bacteria,1MU57@1224|Proteobacteria,1RMCV@1236|Gammaproteobacteria,1XSFT@135623|Vibrionales	135623|Vibrionales	E	COG0626 Cystathionine beta-lyases cystathionine gamma-synthases	metB	-	2.5.1.48	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017	R00999,R01288,R02508,R03217,R03260,R04944,R04945,R04946	RC00020,RC00056,RC00069,RC00420,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000	-	-	-	Cys_Met_Meta_PP
k141_4336_21	945550.VISI1226_11142	0.0	1133.0	COG0460@1|root,COG0527@1|root,COG0460@2|Bacteria,COG0527@2|Bacteria,1MW3H@1224|Proteobacteria,1RN1G@1236|Gammaproteobacteria,1XSVP@135623|Vibrionales	135623|Vibrionales	E	Bifunctional aspartate kinase II homoserine dehydrogenase II	metL	-	1.1.1.3,2.7.2.4	ko:K12525	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00017,M00018,M00526,M00527	R00480,R01773,R01775	RC00002,RC00043,RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,Homoserine_dh,NAD_binding_3
k141_4336_22	1219076.N646_1858	1.79e-193	539.0	COG0685@1|root,COG0685@2|Bacteria,1MUC9@1224|Proteobacteria,1RMXS@1236|Gammaproteobacteria,1XSQ3@135623|Vibrionales	135623|Vibrionales	E	reductase	metF	-	1.5.1.20	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	M00377	R01224,R07168	RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR
k141_4336_23	796620.VIBC2010_03347	3.29e-15	70.9	COG3074@1|root,COG3074@2|Bacteria,1MZJE@1224|Proteobacteria,1S8TG@1236|Gammaproteobacteria,1XYCG@135623|Vibrionales	135623|Vibrionales	D	Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA	zapB	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K09892	-	-	-	-	ko00000,ko03036	-	-	-	ZapB
k141_4336_26	55601.VANGNB10_cI2438c	1.75e-156	446.0	COG0053@1|root,COG0053@2|Bacteria,1MUDS@1224|Proteobacteria,1RNS2@1236|Gammaproteobacteria,1XSMN@135623|Vibrionales	135623|Vibrionales	P	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	fieF	-	-	ko:K13283	-	-	-	-	ko00000,ko02000	2.A.4.7.1	-	-	Cation_efflux,ZT_dimer
k141_4336_27	617140.AJZE01000046_gene564	2.75e-12	68.9	COG3678@1|root,COG3678@2|Bacteria,1RBDH@1224|Proteobacteria,1S2DT@1236|Gammaproteobacteria,1XWIC@135623|Vibrionales	135623|Vibrionales	NPTU	COG3678 P pilus assembly Cpx signaling pathway, periplasmic inhibitor zinc-resistance associated protein	cpxP	-	-	ko:K06006	-	-	-	-	ko00000,ko03110	-	-	-	LTXXQ
k141_4336_28	675813.VIB_000456	2.9e-123	355.0	COG0745@1|root,COG0745@2|Bacteria,1MVCB@1224|Proteobacteria,1RMW7@1236|Gammaproteobacteria,1XSZ6@135623|Vibrionales	135623|Vibrionales	K	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	cpxR	-	-	ko:K07662	ko01503,ko02020,map01503,map02020	M00447,M00727,M00728	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
k141_4336_29	243277.VC_2693	6.64e-189	541.0	COG5002@1|root,COG5002@2|Bacteria,1QUGI@1224|Proteobacteria,1T1Y9@1236|Gammaproteobacteria,1XT99@135623|Vibrionales	135623|Vibrionales	T	sensor protein	cpxA	-	2.7.13.3	ko:K07640	ko01503,ko02020,map01503,map02020	M00447,M00727,M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	CpxA_peri,HAMP,HATPase_c,HisKA
k141_4336_30	672.VV93_v1c28380	2.25e-94	278.0	COG0219@1|root,COG0219@2|Bacteria,1RCY4@1224|Proteobacteria,1S3PI@1236|Gammaproteobacteria,1XUPR@135623|Vibrionales	135623|Vibrionales	J	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide	trmL	-	2.1.1.207	ko:K03216	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
k141_4336_31	223926.28807888	2.05e-60	191.0	COG3030@1|root,COG3030@2|Bacteria,1MZJJ@1224|Proteobacteria,1S8XU@1236|Gammaproteobacteria,1XVK9@135623|Vibrionales	135623|Vibrionales	S	COG3030 Protein affecting phage T7 exclusion by the F plasmid	fxsA	-	-	ko:K07113	-	-	-	-	ko00000	-	-	-	FxsA
k141_4336_32	1219065.VPR01S_26_00400	8.3e-161	482.0	COG2199@1|root,COG2199@2|Bacteria,1P82T@1224|Proteobacteria,1S7Z1@1236|Gammaproteobacteria,1XZQI@135623|Vibrionales	135623|Vibrionales	T	PAS domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
k141_4336_33	345073.VC395_2814	2.75e-211	608.0	COG4232@1|root,COG4232@2|Bacteria,1MU8W@1224|Proteobacteria,1RPF7@1236|Gammaproteobacteria,1XTUK@135623|Vibrionales	135623|Vibrionales	CO	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps	dsbD	GO:0003674,GO:0003756,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0008152,GO:0009987,GO:0015035,GO:0015036,GO:0016020,GO:0016021,GO:0016043,GO:0016491,GO:0016667,GO:0016853,GO:0016860,GO:0016864,GO:0017004,GO:0019725,GO:0022607,GO:0031224,GO:0031226,GO:0034622,GO:0042592,GO:0043933,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0045454,GO:0050789,GO:0050794,GO:0055114,GO:0065003,GO:0065007,GO:0065008,GO:0071840,GO:0071944,GO:0140096	1.8.1.8	ko:K04084	-	-	-	-	ko00000,ko01000,ko03110	5.A.1.1	-	-	DsbC,DsbD,Thioredoxin_7
k141_4336_34	1187848.AJYQ01000075_gene1586	1.83e-121	350.0	COG1738@1|root,COG1738@2|Bacteria,1MVQU@1224|Proteobacteria,1RNX0@1236|Gammaproteobacteria,1XV4J@135623|Vibrionales	135623|Vibrionales	U	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage	yhhQ	-	-	ko:K09125	-	-	-	-	ko00000	-	-	-	Vut_1
k141_4336_35	243277.VC_2708	3.64e-122	353.0	COG0194@1|root,COG0194@2|Bacteria,1MW92@1224|Proteobacteria,1RN09@1236|Gammaproteobacteria,1XSI2@135623|Vibrionales	135623|Vibrionales	F	Essential for recycling GMP and indirectly, cGMP	gmk	GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_kin
k141_4336_40	1123487.KB892834_gene2803	9.83e-44	155.0	COG1246@1|root,COG1595@1|root,COG1246@2|Bacteria,COG1595@2|Bacteria,1RHI0@1224|Proteobacteria,2VRKX@28216|Betaproteobacteria,2KWKE@206389|Rhodocyclales	206389|Rhodocyclales	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
k141_4336_41	1116375.VEJY3_22311	2.14e-174	493.0	COG0701@1|root,COG0701@2|Bacteria,1MUN8@1224|Proteobacteria,1RR9N@1236|Gammaproteobacteria,1XUEG@135623|Vibrionales	135623|Vibrionales	S	Predicted permease	-	-	-	ko:K07089	-	-	-	-	ko00000	-	-	-	ArsP_1
k141_4336_42	580332.Slit_1002	1.87e-27	101.0	COG0526@1|root,COG0526@2|Bacteria,1N728@1224|Proteobacteria,2VWXC@28216|Betaproteobacteria	28216|Betaproteobacteria	CO	Thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_3
k141_4336_43	1238450.VIBNISOn1_420026	2.32e-154	436.0	COG0566@1|root,COG0566@2|Bacteria,1MWCM@1224|Proteobacteria,1RN2F@1236|Gammaproteobacteria,1XU81@135623|Vibrionales	135623|Vibrionales	J	Specifically methylates the ribose of guanosine 2251 in 23S rRNA	rlmB	GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070039,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.185	ko:K03218	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SpoU_methylase,SpoU_sub_bind
k141_4336_44	675815.VOA_003441	0.0	1357.0	COG0557@1|root,COG0557@2|Bacteria,1MUS6@1224|Proteobacteria,1RMQE@1236|Gammaproteobacteria,1XTHJ@135623|Vibrionales	135623|Vibrionales	J	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs	rnr	GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008997,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360	-	ko:K12573	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	HTH_12,OB_RNB,RNB,S1
k141_4336_45	1283284.AZUK01000002_gene2962	2.3e-282	787.0	COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,1RMUR@1236|Gammaproteobacteria,1Y5D7@135624|Aeromonadales	135624|Aeromonadales	V	ABC transporter	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
k141_4336_46	1283284.AZUK01000002_gene2961	6.22e-279	780.0	COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,1RMUR@1236|Gammaproteobacteria,1Y57U@135624|Aeromonadales	135624|Aeromonadales	V	ABC transporter transmembrane region	-	-	-	ko:K18890	ko02010,map02010	M00707	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.106.13,3.A.1.106.5	-	-	ABC_membrane,ABC_tran
k141_4336_49	1484158.PSNIH1_10890	3.31e-48	170.0	COG1446@1|root,COG1446@2|Bacteria,1MWFC@1224|Proteobacteria,1RNUR@1236|Gammaproteobacteria,3VYJN@53335|Pantoea	1236|Gammaproteobacteria	E	peptidase T2 asparaginase 2	iaaA	GO:0003674,GO:0003824,GO:0004067,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0008242,GO:0008798,GO:0010467,GO:0016485,GO:0016540,GO:0016787,GO:0016810,GO:0016811,GO:0019538,GO:0043170,GO:0044238,GO:0051604,GO:0070011,GO:0071704,GO:0140096,GO:1901564	3.4.19.5,3.5.1.1	ko:K01424,ko:K13051	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	-	R00485	RC00010,RC02798	ko00000,ko00001,ko01000,ko01002	-	-	iZ_1308.Z1051m	Asparaginase_2
k141_4336_50	672.VV93_v1c27690	4.34e-85	256.0	COG1047@1|root,COG1047@2|Bacteria,1RD35@1224|Proteobacteria,1S3QR@1236|Gammaproteobacteria,1XSRK@135623|Vibrionales	135623|Vibrionales	G	COG1047 FKBP-type peptidyl-prolyl cis-trans isomerases 2	slyD	GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0006457,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0036211,GO:0042026,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:0140096,GO:1901564	5.2.1.8	ko:K03775	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C
k141_4336_51	55601.VANGNB10_cI2358c	9.14e-302	838.0	COG0475@1|root,COG1226@1|root,COG0475@2|Bacteria,COG1226@2|Bacteria,1MV34@1224|Proteobacteria,1RNVR@1236|Gammaproteobacteria,1XSSX@135623|Vibrionales	135623|Vibrionales	P	Pore-forming subunit of a potassium efflux system that confers protection against electrophiles. Catalyzes K( ) H( ) antiport	kefB	-	-	ko:K11747	-	-	-	-	ko00000,ko02000	2.A.37.1.2	-	-	Na_H_Exchanger,TrkA_N
k141_4336_52	796620.VIBC2010_19410	1.11e-91	272.0	COG2249@1|root,COG2249@2|Bacteria,1MXFT@1224|Proteobacteria,1RMVS@1236|Gammaproteobacteria,1XTQK@135623|Vibrionales	135623|Vibrionales	C	Regulatory subunit of a potassium efflux system that confers protection against electrophiles. Required for full activity of KefB	kefG	-	-	ko:K11748	-	-	-	-	ko00000,ko02000	2.A.37.1.2	-	-	Flavodoxin_2
k141_4336_53	1219077.VAZ01S_063_00160	0.0	972.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,1RPES@1236|Gammaproteobacteria,1XU1H@135623|Vibrionales	135623|Vibrionales	S	COG0488 ATPase components of ABC transporters with duplicated ATPase domains	yheS	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn,CENP-O
k141_4336_54	29495.EA26_19830	1.15e-66	207.0	COG5589@1|root,COG5589@2|Bacteria,1NGHI@1224|Proteobacteria,1SGFT@1236|Gammaproteobacteria,1XT79@135623|Vibrionales	135623|Vibrionales	S	Protein of unknown function (DUF2390)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2390
k141_4336_55	675816.VIA_000452	9.13e-28	102.0	COG3089@1|root,COG3089@2|Bacteria,1N6TM@1224|Proteobacteria,1SCDE@1236|Gammaproteobacteria,1XYYU@135623|Vibrionales	135623|Vibrionales	S	Belongs to the UPF0270 family	-	-	-	ko:K09898	-	-	-	-	ko00000	-	-	-	UPF0270
k141_4336_58	1219065.VPR01S_04_01180	6.03e-114	335.0	COG5383@1|root,COG5383@2|Bacteria,1MWTV@1224|Proteobacteria,1RNJF@1236|Gammaproteobacteria,1XTHF@135623|Vibrionales	135623|Vibrionales	S	DUF1338	-	-	-	-	-	-	-	-	-	-	-	-	DUF1338
k141_4336_59	1517681.HW45_26985	2.53e-243	681.0	COG1012@1|root,COG1012@2|Bacteria,1MV2I@1224|Proteobacteria,1RPQW@1236|Gammaproteobacteria,1XTD0@135623|Vibrionales	135623|Vibrionales	C	Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate	astD	GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016491,GO:0016620,GO:0016903,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0055114,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	1.2.1.71	ko:K06447	ko00330,ko01100,map00330,map01100	-	R05049	RC00080	ko00000,ko00001,ko01000	-	-	-	Aldedh
k141_4336_60	945550.VISI1226_20210	1.69e-170	484.0	COG3138@1|root,COG3138@2|Bacteria,1MWHC@1224|Proteobacteria,1RMXG@1236|Gammaproteobacteria,1XSR5@135623|Vibrionales	135623|Vibrionales	H	COG3138 Arginine ornithine N-succinyltransferase beta subunit	astA	-	2.3.1.109	ko:K00673	ko00330,ko01100,map00330,map01100	-	R00832	RC00004,RC00064	ko00000,ko00001,ko01000	-	-	-	AstA
k141_4336_62	674977.VMC_01670	3.97e-104	305.0	COG0512@1|root,COG0512@2|Bacteria,1MV5Y@1224|Proteobacteria,1RMQW@1236|Gammaproteobacteria,1XUV5@135623|Vibrionales	135623|Vibrionales	EH	COG0512 Anthranilate para-aminobenzoate synthases component II	pabA	-	2.6.1.85	ko:K01664	ko00790,map00790	-	R01716	RC00010,RC01418	ko00000,ko00001,ko01000	-	-	-	GATase
k141_4336_64	1191299.AJYX01000051_gene1222	1.09e-94	283.0	COG0546@1|root,COG0546@2|Bacteria,1RDDY@1224|Proteobacteria,1S3QD@1236|Gammaproteobacteria,1XUKY@135623|Vibrionales	135623|Vibrionales	G	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress	gph	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008967,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
k141_4336_65	345073.VC395_2738	5.15e-143	405.0	COG0036@1|root,COG0036@2|Bacteria,1MUZM@1224|Proteobacteria,1RN3K@1236|Gammaproteobacteria,1XU07@135623|Vibrionales	135623|Vibrionales	G	Belongs to the ribulose-phosphate 3-epimerase family	rpe	-	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
k141_4336_66	1205908.AKXW01000019_gene1039	3.23e-164	463.0	COG0338@1|root,COG0338@2|Bacteria,1P85S@1224|Proteobacteria,1RMNW@1236|Gammaproteobacteria,1XV7I@135623|Vibrionales	135623|Vibrionales	H	Site-specific DNA-methyltransferase (adenine-specific)	dam	-	2.1.1.72	ko:K06223	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko02048,ko03032,ko03400	-	-	-	MethyltransfD12
k141_4336_67	1187848.AJYQ01000109_gene449	1.13e-141	423.0	COG3266@1|root,COG3267@1|root,COG3266@2|Bacteria,COG3267@2|Bacteria,1Q1YI@1224|Proteobacteria,1S965@1236|Gammaproteobacteria,1XSV9@135623|Vibrionales	135623|Vibrionales	U	AAA domain	VP2743	-	-	ko:K03112	-	-	-	-	ko00000	-	-	-	AAA_22,SPOR
k141_4336_68	1136163.M565_ctg4P139	6.98e-207	578.0	COG0337@1|root,COG0337@2|Bacteria,1MUBK@1224|Proteobacteria,1RN4I@1236|Gammaproteobacteria,1XU0D@135623|Vibrionales	135623|Vibrionales	E	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	GO:0003674,GO:0003824,GO:0003856,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576	4.2.3.4	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03083	RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase
k141_4336_70	243277.VC_2630	2.15e-118	362.0	COG4796@1|root,COG4796@2|Bacteria,1QTT6@1224|Proteobacteria,1RN3Z@1236|Gammaproteobacteria,1XSBC@135623|Vibrionales	135623|Vibrionales	U	COG4796 Type II secretory pathway, component HofQ	pilQ	-	-	ko:K02666	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	STN,Secretin,Secretin_N
k141_4336_74	675815.VOA_003479	0.0	1146.0	COG5009@1|root,COG5009@2|Bacteria,1MU5A@1224|Proteobacteria,1RM7J@1236|Gammaproteobacteria,1XT2B@135623|Vibrionales	135623|Vibrionales	M	COG5009 Membrane carboxypeptidase penicillin-binding protein	mrcA	GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	PCB_OB,Transgly,Transpeptidase
k141_4336_80	675814.VIC_000093	3.02e-114	335.0	COG0548@1|root,COG0548@2|Bacteria,1MU17@1224|Proteobacteria,1RNKK@1236|Gammaproteobacteria,1XSF2@135623|Vibrionales	135623|Vibrionales	F	Belongs to the acetylglutamate kinase family. ArgB subfamily	argB	GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.2.8	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R02649	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
k141_4336_81	1348635.BBJY01000009_gene1551	6.62e-191	535.0	COG0002@1|root,COG0002@2|Bacteria,1MVJ6@1224|Proteobacteria,1RNMX@1236|Gammaproteobacteria,1XSZ0@135623|Vibrionales	135623|Vibrionales	E	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde	argC	GO:0003674,GO:0003824,GO:0003942,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.2.1.38	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R03443	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
k141_4336_82	1280001.BAOA01000134_gene2096	5.03e-229	635.0	COG0624@1|root,COG0624@2|Bacteria,1MVBR@1224|Proteobacteria,1RNDG@1236|Gammaproteobacteria,1XVA2@135623|Vibrionales	135623|Vibrionales	E	Belongs to the peptidase M20A family. ArgE subfamily	argE	GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008777,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016787,GO:0016810,GO:0016811,GO:0019213,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	3.5.1.16	ko:K01438	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R00669,R09107	RC00064,RC00300	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20
k141_4336_83	55601.VANGNB10_cI2399	0.0	1494.0	COG2352@1|root,COG2352@2|Bacteria,1MUD5@1224|Proteobacteria,1RPTP@1236|Gammaproteobacteria,1XUG5@135623|Vibrionales	135623|Vibrionales	H	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle	ppc	GO:0003674,GO:0003824,GO:0004611,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0008964,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016830,GO:0016831,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0055114,GO:0071704,GO:0072350	4.1.1.31	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	M00168,M00170,M00171,M00172,M00173,M00346,M00374	R00345	RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPcase
k141_4336_84	1191299.AJYX01000051_gene1245	3.11e-94	278.0	COG1695@1|root,COG1695@2|Bacteria,1MZYS@1224|Proteobacteria,1S9RS@1236|Gammaproteobacteria,1XV2U@135623|Vibrionales	135623|Vibrionales	K	transcriptional regulators	aphA	-	-	ko:K10917	ko02024,ko05111,map02024,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	PadR,Vir_act_alpha_C
k141_4336_86	674977.VMC_23520	1.12e-201	563.0	COG0240@1|root,COG0240@2|Bacteria,1MUU3@1224|Proteobacteria,1RPQ7@1236|Gammaproteobacteria,1XSBF@135623|Vibrionales	135623|Vibrionales	I	Glycerol-3-phosphate dehydrogenase	gpsA	GO:0003674,GO:0003824,GO:0004367,GO:0006072,GO:0006629,GO:0006644,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0052646,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	-	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
k141_4336_87	1219080.VEZ01S_45_00260	1.03e-87	260.0	COG1952@1|root,COG1952@2|Bacteria,1RI75@1224|Proteobacteria,1S62H@1236|Gammaproteobacteria,1XU1J@135623|Vibrionales	135623|Vibrionales	U	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA	secB	GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705	-	ko:K03071	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03110	3.A.5	-	-	SecB
k141_4336_88	1116375.VEJY3_14415	1.79e-67	207.0	COG0607@1|root,COG0607@2|Bacteria,1MZ83@1224|Proteobacteria,1S8ZI@1236|Gammaproteobacteria,1XWWT@135623|Vibrionales	135623|Vibrionales	P	rhodanese-related sulfurtransferase	yibN	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
k141_4336_89	55601.VANGNB10_cI2405c	4.36e-164	466.0	COG2269@1|root,COG2269@2|Bacteria,1MU97@1224|Proteobacteria,1RMR9@1236|Gammaproteobacteria,1XSYN@135623|Vibrionales	135623|Vibrionales	J	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P	epmA	GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006430,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576	-	ko:K04568	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	tRNA-synt_2
k141_4062_24	1190603.AJYD01000033_gene1831	5.07e-69	238.0	COG1566@1|root,COG1566@2|Bacteria,1Q1PW@1224|Proteobacteria,1TIVN@1236|Gammaproteobacteria,1XZSS@135623|Vibrionales	135623|Vibrionales	V	HlyD family secretion protein	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_3
k141_4062_25	42565.FP66_10510	1.54e-104	333.0	COG1215@1|root,COG1215@2|Bacteria,1NQ1J@1224|Proteobacteria,1RYM8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	COG1215 Glycosyltransferases, probably involved in cell wall biogenesis	alg8	-	2.4.1.33	ko:K19290	ko00051,map00051	-	R08692	RC00005	ko00000,ko00001,ko01000,ko01003,ko02000	4.D.1.1.7,4.D.1.1.9	GT2	-	Glyco_tranf_2_3
k141_4062_27	1500897.JQNA01000002_gene1183	5.5e-42	160.0	COG0477@1|root,COG0477@2|Bacteria,1MU46@1224|Proteobacteria,2VIPI@28216|Betaproteobacteria,1KBW7@119060|Burkholderiaceae	28216|Betaproteobacteria	EGP	Major Facilitator Superfamily	-	-	-	ko:K03762	-	-	-	-	ko00000,ko02000	2.A.1.6.4	-	-	MFS_1
k141_4062_30	223926.28809970	2.77e-145	417.0	COG1180@1|root,COG1180@2|Bacteria,1QJHU@1224|Proteobacteria,1RQUF@1236|Gammaproteobacteria,1XVM7@135623|Vibrionales	135623|Vibrionales	O	4Fe-4S single cluster domain	-	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
k141_4062_31	675817.VDA_000905	0.0	1350.0	COG1882@1|root,COG1882@2|Bacteria,1MWBF@1224|Proteobacteria,1RMEK@1236|Gammaproteobacteria,1XT51@135623|Vibrionales	135623|Vibrionales	C	Pyruvate formate lyase-like	-	-	2.3.1.54	ko:K00656	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	-	R00212,R06987	RC00004,RC01181,RC02742,RC02833	ko00000,ko00001,ko01000	-	-	-	Gly_radical,PFL-like
k141_4062_32	1219065.VPR01S_11_01360	8.19e-111	325.0	COG1349@1|root,COG1349@2|Bacteria,1MV49@1224|Proteobacteria,1RRR5@1236|Gammaproteobacteria,1XWBG@135623|Vibrionales	135623|Vibrionales	K	DeoR C terminal sensor domain	-	-	-	-	-	-	-	-	-	-	-	-	DeoRC,HTH_DeoR
k141_4062_33	675813.VIB_000919	1.1e-209	601.0	COG2194@1|root,COG2194@2|Bacteria,1MWS7@1224|Proteobacteria,1RMNG@1236|Gammaproteobacteria,1XSQM@135623|Vibrionales	135623|Vibrionales	S	membrane-associated, metal-dependent hydrolase	-	-	2.7.8.43	ko:K03760	ko01503,map01503	M00722	R11555,R11556,R11557	RC00002	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	DUF1705,Sulfatase
k141_4062_34	223926.28809648	7.93e-226	642.0	COG2194@1|root,COG2194@2|Bacteria,1MWS7@1224|Proteobacteria,1RMNG@1236|Gammaproteobacteria,1XSQM@135623|Vibrionales	135623|Vibrionales	S	membrane-associated, metal-dependent hydrolase	eptA	-	2.7.8.43	ko:K03760	ko01503,map01503	M00722	R11555,R11556,R11557	RC00002	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	DUF1705,Sulfatase
k141_4062_35	1224318.DT73_01760	7.29e-37	128.0	COG0818@1|root,COG0818@2|Bacteria,1MZ3Q@1224|Proteobacteria,1S92I@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Recycling of diacylglycerol produced during the turnover of membrane phospholipid	dgkA	GO:0003674,GO:0003824,GO:0004143,GO:0005575,GO:0005623,GO:0005886,GO:0006629,GO:0006644,GO:0006650,GO:0006654,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0045017,GO:0046473,GO:0046474,GO:0046486,GO:0050896,GO:0071704,GO:0071944,GO:0090407,GO:1901576	2.7.1.107	ko:K00901	ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00561,map00564,map01100,map01110,map04070,map04072,map05231	-	R02240	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	DAGK_prokar
k141_4364_1	439235.Dalk_4835	2.75e-72	233.0	COG0845@1|root,COG0845@2|Bacteria,1MU78@1224|Proteobacteria,42NHV@68525|delta/epsilon subdivisions,2WJBA@28221|Deltaproteobacteria,2MHST@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	acrA	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	Biotin_lipoyl_2,HlyD,HlyD_3,HlyD_D23
k141_4364_2	1121405.dsmv_1339	9.45e-87	281.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2WJVV@28221|Deltaproteobacteria,2MI7E@213118|Desulfobacterales	28221|Deltaproteobacteria	V	Hydrophobe Amphiphile Efflux-1 (HAE1) Family	acrB	-	-	ko:K03296,ko:K18138	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
k141_1634_1	1121405.dsmv_1440	7.46e-120	370.0	COG0557@1|root,COG0557@2|Bacteria,1MUS6@1224|Proteobacteria,42NHP@68525|delta/epsilon subdivisions,2X6U1@28221|Deltaproteobacteria,2MHMI@213118|Desulfobacterales	28221|Deltaproteobacteria	K	PFAM ribonuclease II	-	-	3.1.13.1	ko:K01147,ko:K12573	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	OB_RNB,RNB,S1
k141_1634_2	1515746.HR45_12945	3.09e-14	73.9	COG1119@1|root,COG1119@2|Bacteria,1MVVM@1224|Proteobacteria,1RMXK@1236|Gammaproteobacteria,2QAYS@267890|Shewanellaceae	1236|Gammaproteobacteria	P	PFAM ABC transporter related	modF	GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0008144,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363	3.6.3.34	ko:K02013,ko:K05776	ko02010,map02010	M00189,M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	ABC_tran
k141_1635_1	96561.Dole_1102	1.27e-20	96.3	COG0628@1|root,COG0628@2|Bacteria,1MVX7@1224|Proteobacteria,42N2T@68525|delta/epsilon subdivisions,2WMYV@28221|Deltaproteobacteria,2MI58@213118|Desulfobacterales	28221|Deltaproteobacteria	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
k141_2971_1	386456.JQKN01000001_gene2216	5.93e-05	44.7	COG2303@1|root,arCOG02232@2157|Archaea,2XUKH@28890|Euryarchaeota,23PYT@183925|Methanobacteria	183925|Methanobacteria	E	GMC oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GMC_oxred_C,GMC_oxred_N
k141_2971_2	452662.SJA_C2-01170	3.09e-14	84.7	COG4773@1|root,COG4773@2|Bacteria,1QTXJ@1224|Proteobacteria,2U2G4@28211|Alphaproteobacteria,2KEBD@204457|Sphingomonadales	204457|Sphingomonadales	P	PFAM TonB-dependent Receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
k141_5320_1	1348635.BBJY01000007_gene175	2.99e-170	498.0	COG0550@1|root,COG0550@2|Bacteria,1MUFZ@1224|Proteobacteria,1RN4X@1236|Gammaproteobacteria,1XUYY@135623|Vibrionales	135623|Vibrionales	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topB	GO:0003674,GO:0003824,GO:0003916,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016853,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360	5.99.1.2	ko:K03169	-	-	-	-	ko00000,ko01000,ko03032	-	-	-	Topoisom_bac,Toprim
k141_5320_2	1140.Synpcc7942_1355	5.1e-75	270.0	COG5001@1|root,COG5001@2|Bacteria,1G0SY@1117|Cyanobacteria,1GYX2@1129|Synechococcus	1117|Cyanobacteria	T	diguanylate cyclase (GGDEF) domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_8,PAS_9,Response_reg
k141_5320_3	1348635.BBJY01000003_gene3869	1.17e-115	345.0	COG0687@1|root,COG0687@2|Bacteria,1MUYW@1224|Proteobacteria,1RM7W@1236|Gammaproteobacteria,1XX29@135623|Vibrionales	135623|Vibrionales	E	Bacterial extracellular solute-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_8
k141_5320_4	382245.ASA_4151	4.9e-12	66.2	COG0518@1|root,COG0518@2|Bacteria,1MV9U@1224|Proteobacteria,1S2MK@1236|Gammaproteobacteria,1Y6BK@135624|Aeromonadales	135624|Aeromonadales	F	glutamine amidotransferase	-	-	-	-	-	-	-	-	-	-	-	-	GATase
k141_5320_5	1205908.AKXW01000151_gene2185	2.07e-11	64.3	COG0518@1|root,COG0518@2|Bacteria,1MV9U@1224|Proteobacteria,1S2MK@1236|Gammaproteobacteria,1XTR7@135623|Vibrionales	135623|Vibrionales	F	Glutamine amidotransferase class-I	-	-	-	-	-	-	-	-	-	-	-	-	GATase
k141_1637_1	1410626.JHXB01000009_gene1642	1.88e-09	61.6	COG2812@1|root,COG2812@2|Bacteria,1VCQC@1239|Firmicutes,248U4@186801|Clostridia,27IHW@186928|unclassified Lachnospiraceae	186801|Clostridia	L	DNA polymerase III, delta subunit	holB	-	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNApol3-delta_C
k141_1637_2	293826.Amet_0085	4.6e-69	217.0	COG1774@1|root,COG1774@2|Bacteria,1TP1V@1239|Firmicutes,247Q6@186801|Clostridia,36EJN@31979|Clostridiaceae	186801|Clostridia	S	PSP1 domain protein	yaaT	-	-	-	-	-	-	-	-	-	-	-	PSP1
k141_2650_1	1219076.N646_2325	3.42e-82	245.0	COG2165@1|root,COG2165@2|Bacteria,1RDX2@1224|Proteobacteria,1S3VS@1236|Gammaproteobacteria,1XWYF@135623|Vibrionales	135623|Vibrionales	U	general secretion pathway protein	epsG	GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,T2SSG
k141_2650_2	674977.VMC_02760	1.7e-29	115.0	COG2165@1|root,COG2165@2|Bacteria,1N7HZ@1224|Proteobacteria,1SCWD@1236|Gammaproteobacteria,1XWQW@135623|Vibrionales	135623|Vibrionales	NU	COG2165 Type II secretory pathway, pseudopilin PulG	epsH	GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705	-	ko:K02457	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	GspH,N_methyl
k141_2650_3	617140.AJZE01000111_gene632	9.12e-41	139.0	COG2165@1|root,COG2165@2|Bacteria,1N737@1224|Proteobacteria,1SC8X@1236|Gammaproteobacteria,1XXW2@135623|Vibrionales	135623|Vibrionales	NU	COG2165 Type II secretory pathway, pseudopilin PulG	epsI	GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705	-	ko:K02458	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,T2SSI
k141_2650_4	1188252.AJYK01000120_gene971	1.16e-57	188.0	COG4795@1|root,COG4795@2|Bacteria,1RJAE@1224|Proteobacteria,1S5ZZ@1236|Gammaproteobacteria,1XU01@135623|Vibrionales	135623|Vibrionales	U	general secretion pathway protein	epsJ	GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015628,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0098776	-	ko:K02459	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,T2SSJ
k141_1071_2	1072685.IX83_01995	1.64e-19	96.3	COG1372@1|root,COG3210@1|root,COG1372@2|Bacteria,COG3210@2|Bacteria,1MX2K@1224|Proteobacteria,2VI40@28216|Betaproteobacteria,3T2WR@506|Alcaligenaceae	28216|Betaproteobacteria	U	Haemagluttinin repeat	-	-	-	ko:K15125	ko05133,map05133	-	-	-	ko00000,ko00001,ko00536	-	-	-	ESPR,Fil_haemagg,Fil_haemagg_2,Haemagg_act,PT-VENN
k141_2097_1	1348635.BBJY01000012_gene1133	1.05e-54	174.0	COG0789@1|root,COG0789@2|Bacteria,1RGX6@1224|Proteobacteria,1SZ1C@1236|Gammaproteobacteria,1Y26I@135623|Vibrionales	135623|Vibrionales	K	Regulates the transcription of the copA and cueO genes. It detects cytoplasmic copper stress and activates transcription in response to increasing copper concentrations (By similarity)	cueR	-	-	ko:K19591	-	M00769	-	-	ko00000,ko00002,ko01504,ko03000	-	-	-	MerR,MerR-DNA-bind,MerR_1
k141_2097_2	1121878.AUGL01000001_gene281	3.52e-17	80.5	COG1585@1|root,COG1585@2|Bacteria	2|Bacteria	OU	cellular response to DNA damage stimulus	ybbJ	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K07340	-	-	-	-	ko00000	-	-	-	NfeD
k141_2097_3	1348635.BBJY01000012_gene1130	5.38e-121	354.0	COG3118@1|root,COG3118@2|Bacteria,1MV0R@1224|Proteobacteria,1RMSQ@1236|Gammaproteobacteria,1XST1@135623|Vibrionales	135623|Vibrionales	O	COG3118 Thioredoxin domain-containing protein	ybbN	-	-	ko:K05838	-	-	-	-	ko00000,ko03110	-	-	-	TPR_19,TPR_20,Thioredoxin
k141_2097_4	243277.VC_0979	4.97e-138	397.0	COG1028@1|root,COG1028@2|Bacteria,1MUCH@1224|Proteobacteria,1RNAA@1236|Gammaproteobacteria,1XTR2@135623|Vibrionales	135623|Vibrionales	IQ	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	ybbO	-	-	-	-	-	-	-	-	-	-	-	adh_short
k141_2097_5	223926.28805795	1.56e-144	416.0	COG1090@1|root,COG1090@2|Bacteria,1MUB4@1224|Proteobacteria,1RN6A@1236|Gammaproteobacteria,1XSDX@135623|Vibrionales	135623|Vibrionales	S	nucleoside-diphosphate sugar epimerase	yfcH	-	-	ko:K07071	-	-	-	-	ko00000	-	-	-	DUF1731,Epimerase
k141_2097_6	1198232.CYCME_0656	2.11e-06	49.7	arCOG03638@1|root,2Z7NN@2|Bacteria,1R3Y6@1224|Proteobacteria,1RTWY@1236|Gammaproteobacteria,460KA@72273|Thiotrichales	72273|Thiotrichales	S	Protein of unknown function (DUF1538)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1538
k141_1782_1	1116375.VEJY3_08675	1.67e-91	275.0	COG0673@1|root,COG0673@2|Bacteria,1NQ54@1224|Proteobacteria,1RZTE@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose)	iolG	-	1.1.1.18,1.1.1.369	ko:K00010	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	-	R01183,R09951	RC00182	ko00000,ko00001,ko01000	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
k141_1782_2	1116375.VEJY3_08595	2.26e-204	577.0	COG0477@1|root,COG2814@2|Bacteria,1MVKJ@1224|Proteobacteria,1RMHJ@1236|Gammaproteobacteria,1XUMU@135623|Vibrionales	135623|Vibrionales	P	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family	-	-	-	ko:K08138	-	-	-	-	ko00000,ko02000	2.A.1.1.3	-	-	Sugar_tr
k141_138_1	1087481.AGFX01000023_gene2246	1.12e-19	81.6	2DMNG@1|root,32SP1@2|Bacteria,1VAXC@1239|Firmicutes,4HM1Q@91061|Bacilli,26ZFG@186822|Paenibacillaceae	91061|Bacilli	S	COG NOG14552 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_1783_1	439235.Dalk_3509	5.65e-22	103.0	COG1372@1|root,COG3209@1|root,COG1372@2|Bacteria,COG3209@2|Bacteria,1MVV1@1224|Proteobacteria,42MK6@68525|delta/epsilon subdivisions,2WKN2@28221|Deltaproteobacteria,2MIC4@213118|Desulfobacterales	28221|Deltaproteobacteria	M	RHS protein	-	-	-	-	-	-	-	-	-	-	-	-	RHS,RHS_repeat
k141_454_1	1121445.ATUZ01000015_gene1699	2.34e-169	509.0	COG1455@1|root,COG2200@1|root,COG1455@2|Bacteria,COG2200@2|Bacteria,1MXAG@1224|Proteobacteria,42N1E@68525|delta/epsilon subdivisions,2WTVW@28221|Deltaproteobacteria,2M88X@213115|Desulfovibrionales	28221|Deltaproteobacteria	GT	Phosphotransferase system, EIIC	-	-	-	-	-	-	-	-	-	-	-	-	EAL,PTS_EIIC
k141_4809_1	1035196.HMPREF9998_01417	3.95e-107	313.0	COG0740@1|root,COG0740@2|Bacteria,1TQ91@1239|Firmicutes,247QY@186801|Clostridia,25QQZ@186804|Peptostreptococcaceae	186801|Clostridia	OU	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
k141_4809_2	1121324.CLIT_23c01000	1.03e-241	672.0	COG1219@1|root,COG1219@2|Bacteria,1TQ00@1239|Firmicutes,2481T@186801|Clostridia,25QFC@186804|Peptostreptococcaceae	186801|Clostridia	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	-	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
k141_4809_3	994573.T472_0215605	1.33e-39	139.0	COG2059@1|root,COG2059@2|Bacteria,1V42U@1239|Firmicutes,24HA0@186801|Clostridia,36ICK@31979|Clostridiaceae	186801|Clostridia	P	Chromate	-	-	-	ko:K07240	-	-	-	-	ko00000,ko02000	2.A.51.1	-	-	Chromate_transp
k141_4809_4	1151292.QEW_3952	6.63e-47	157.0	COG2059@1|root,COG2059@2|Bacteria,1V43H@1239|Firmicutes,24JTX@186801|Clostridia,25TCU@186804|Peptostreptococcaceae	186801|Clostridia	P	Chromate transporter	chrA	-	-	ko:K07240	-	-	-	-	ko00000,ko02000	2.A.51.1	-	-	Chromate_transp
k141_4809_5	1286171.EAL2_c16240	0.0	1000.0	COG0466@1|root,COG0466@2|Bacteria,1TNYG@1239|Firmicutes,247SH@186801|Clostridia,25VQG@186806|Eubacteriaceae	186801|Clostridia	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
k141_4809_6	1476973.JMMB01000007_gene3145	1.5e-101	298.0	COG0218@1|root,COG0218@2|Bacteria,1TSPW@1239|Firmicutes,24836@186801|Clostridia,25QD6@186804|Peptostreptococcaceae	186801|Clostridia	D	Necessary for normal cell division and for the maintenance of normal septation	engB	-	-	ko:K03978	-	-	-	-	ko00000,ko03036	-	-	-	MMR_HSR1
k141_4809_8	1286171.EAL2_c16190	3.21e-52	175.0	COG3879@1|root,COG3879@2|Bacteria,1VDG3@1239|Firmicutes,24PW0@186801|Clostridia	186801|Clostridia	S	Bacterial protein of unknown function (DUF881)	-	-	-	-	-	-	-	-	-	-	-	-	DUF881
k141_4809_10	1301100.HG529382_gene4017	1.01e-211	604.0	COG2509@1|root,COG2509@2|Bacteria,1TPBW@1239|Firmicutes,247TR@186801|Clostridia,36DE1@31979|Clostridiaceae	186801|Clostridia	S	Oxidoreductase	-	-	-	ko:K07137	-	-	-	-	ko00000	-	-	-	HI0933_like,NAD_binding_8,Pyr_redox_2
k141_4809_11	1121324.CLIT_23c01120	1.06e-245	691.0	COG1283@1|root,COG1283@2|Bacteria,1TP4K@1239|Firmicutes,247KT@186801|Clostridia,25QKI@186804|Peptostreptococcaceae	186801|Clostridia	P	Na Pi-cotransporter II-like protein	-	-	-	ko:K03324	-	-	-	-	ko00000,ko02000	2.A.58.2	-	-	Na_Pi_cotrans,PhoU
k141_4809_12	1487921.DP68_10000	1.23e-195	559.0	COG3104@1|root,COG3104@2|Bacteria,1TP81@1239|Firmicutes,24BI4@186801|Clostridia,36FG1@31979|Clostridiaceae	186801|Clostridia	P	amino acid peptide transporter	-	-	-	ko:K03305	-	-	-	-	ko00000	2.A.17	-	-	PTR2
k141_4809_13	7425.NV16146-PA	8.26e-79	247.0	COG0388@1|root,KOG0806@2759|Eukaryota,38TQE@33154|Opisthokonta,3B9AV@33208|Metazoa,3CSJF@33213|Bilateria,41TCG@6656|Arthropoda,3SFRS@50557|Insecta,46HRD@7399|Hymenoptera	33208|Metazoa	E	Carbon-nitrogen hydrolase	NIT2	GO:0001775,GO:0002252,GO:0002263,GO:0002274,GO:0002275,GO:0002283,GO:0002366,GO:0002376,GO:0002443,GO:0002444,GO:0002446,GO:0003674,GO:0003824,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005813,GO:0005815,GO:0005829,GO:0005856,GO:0006082,GO:0006107,GO:0006520,GO:0006528,GO:0006541,GO:0006807,GO:0006810,GO:0006887,GO:0006955,GO:0008150,GO:0008152,GO:0009064,GO:0009066,GO:0009987,GO:0012505,GO:0015630,GO:0016192,GO:0016787,GO:0016810,GO:0016811,GO:0019752,GO:0030141,GO:0031410,GO:0031974,GO:0031982,GO:0031983,GO:0032787,GO:0032940,GO:0034641,GO:0034774,GO:0035580,GO:0036230,GO:0042119,GO:0042581,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043232,GO:0043233,GO:0043299,GO:0043312,GO:0043436,GO:0043603,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0044422,GO:0044424,GO:0044430,GO:0044433,GO:0044444,GO:0044446,GO:0044464,GO:0045055,GO:0045321,GO:0046903,GO:0050152,GO:0050896,GO:0051179,GO:0051234,GO:0060205,GO:0070013,GO:0070820,GO:0071704,GO:0097708,GO:0099503,GO:1901564,GO:1901605,GO:1904724	3.5.1.3	ko:K13101,ko:K13566	ko00250,map00250	-	R00269,R00348	RC00010	ko00000,ko00001,ko01000,ko03041	-	-	-	CN_hydrolase
k141_4809_14	1151292.QEW_3934	5.91e-227	636.0	COG0166@1|root,COG0166@2|Bacteria,1TP29@1239|Firmicutes,2487A@186801|Clostridia,25QK4@186804|Peptostreptococcaceae	186801|Clostridia	G	Belongs to the GPI family	pgi	-	5.3.1.9	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI
k141_4809_15	1286171.EAL2_c16130	3.33e-38	134.0	COG0589@1|root,COG0589@2|Bacteria,1VZCK@1239|Firmicutes,253YG@186801|Clostridia,25Z3J@186806|Eubacteriaceae	2|Bacteria	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
k141_4809_17	509191.AEDB02000109_gene5081	2.3e-228	659.0	COG0643@1|root,COG0643@2|Bacteria,1TPMS@1239|Firmicutes,24858@186801|Clostridia,3WH05@541000|Ruminococcaceae	186801|Clostridia	NT	Signal transducing histidine kinase homodimeric	cheA	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt,P2
k141_4809_18	203119.Cthe_3029	5.01e-36	130.0	COG0835@1|root,COG0835@2|Bacteria,1V431@1239|Firmicutes,24HHD@186801|Clostridia,3WP6Y@541000|Ruminococcaceae	186801|Clostridia	NT	Two component signalling adaptor domain	-	-	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
k141_3994_6	1191299.AJYX01000099_gene785	2.92e-65	201.0	COG3205@1|root,COG3205@2|Bacteria,1N85D@1224|Proteobacteria,1SCCN@1236|Gammaproteobacteria,1XXCR@135623|Vibrionales	135623|Vibrionales	S	Predicted membrane protein (DUF2061)	VP2647	-	-	-	-	-	-	-	-	-	-	-	DUF2061
k141_3994_7	1187848.AJYQ01000079_gene1233	1.6e-18	83.2	COG0547@1|root,COG0547@2|Bacteria,1QJ8Q@1224|Proteobacteria,1RY26@1236|Gammaproteobacteria,1XTQE@135623|Vibrionales	135623|Vibrionales	E	Glycosyl transferase family, helical bundle domain	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_trans_3N,Glycos_transf_3
k141_3994_8	1191299.AJYX01000067_gene3773	6.43e-09	55.8	COG0547@1|root,COG0547@2|Bacteria,1QJ8Q@1224|Proteobacteria,1RY26@1236|Gammaproteobacteria,1XTQE@135623|Vibrionales	135623|Vibrionales	E	Glycosyl transferase family, helical bundle domain	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_trans_3N,Glycos_transf_3
k141_3994_9	1348635.BBJY01000004_gene2971	4.54e-114	337.0	COG0007@1|root,COG0007@2|Bacteria,1RBE1@1224|Proteobacteria,1SYIY@1236|Gammaproteobacteria,1XTGC@135623|Vibrionales	135623|Vibrionales	H	Belongs to the precorrin methyltransferase family	-	-	2.1.1.107	ko:K02303	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03194	RC00003,RC00871	ko00000,ko00001,ko00002,ko01000	-	-	-	TP_methylase
k141_5256_2	998088.B565_2787	1.15e-110	326.0	COG1028@1|root,COG1028@2|Bacteria,1R5GA@1224|Proteobacteria,1RZ92@1236|Gammaproteobacteria	1236|Gammaproteobacteria	N	with different specificities (Related to short-chain alcohol	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
k141_5256_3	1121939.L861_02445	9.48e-76	241.0	COG0673@1|root,COG0673@2|Bacteria,1RJ53@1224|Proteobacteria	1224|Proteobacteria	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
k141_5256_4	537971.HCCG_01088	2.17e-68	219.0	COG0300@1|root,COG0300@2|Bacteria	2|Bacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	cmrA	-	-	ko:K07124	-	-	-	-	ko00000	-	-	-	adh_short
k141_5256_5	537971.HCCG_01089	6.67e-44	154.0	COG1083@1|root,COG1083@2|Bacteria,1QACI@1224|Proteobacteria	1224|Proteobacteria	M	Acylneuraminate cytidylyltransferase	neuA	-	2.7.7.43,2.7.7.82	ko:K00983,ko:K18431	ko00520,ko01100,map00520,map01100	-	R01117,R04215,R10182	RC00152	ko00000,ko00001,ko01000	-	-	-	CTP_transf_3,Lipase_GDSL_2
k141_5256_6	312309.VF_0145	5.98e-194	545.0	COG0517@1|root,COG1208@1|root,COG0517@2|Bacteria,COG1208@2|Bacteria,1MUYJ@1224|Proteobacteria,1RQPI@1236|Gammaproteobacteria,1XSMC@135623|Vibrionales	135623|Vibrionales	M	Nucleotidyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	CBS,NTP_transferase
k141_5256_7	1121434.AULY01000013_gene91	2.36e-138	400.0	COG0223@1|root,COG0223@2|Bacteria,1MWH1@1224|Proteobacteria,42M1P@68525|delta/epsilon subdivisions,2X6C3@28221|Deltaproteobacteria,2MD6Q@213115|Desulfovibrionales	28221|Deltaproteobacteria	J	Formyl transferase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Formyl_trans_C,Formyl_trans_N
k141_5256_8	1005994.GTGU_04528	1.16e-174	496.0	COG2089@1|root,COG2089@2|Bacteria,1MWG3@1224|Proteobacteria,1RPIG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	acid) synthase	neuB	GO:0003674,GO:0003824,GO:0005975,GO:0008150,GO:0008152,GO:0009058,GO:0016051,GO:0016740,GO:0016765,GO:0044238,GO:0071704,GO:1901576	2.5.1.101,2.5.1.56	ko:K01654,ko:K18430	ko00520,ko01100,map00520,map01100	-	R01804,R04435,R10304	RC00159	ko00000,ko00001,ko01000	-	-	-	NeuB,SAF
k141_5256_9	223926.28805181	8.38e-220	613.0	COG0381@1|root,COG0381@2|Bacteria,1MWZN@1224|Proteobacteria,1THG0@1236|Gammaproteobacteria,1XVI6@135623|Vibrionales	135623|Vibrionales	M	UDP-N-acetylglucosamine 2-epimerase	-	-	5.1.3.14	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	M00362	R00420	RC00290	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase_2
k141_5256_10	1280001.BAOA01000021_gene697	1.05e-230	640.0	COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,1RPFX@1236|Gammaproteobacteria,1XUVN@135623|Vibrionales	135623|Vibrionales	E	DegT/DnrJ/EryC1/StrS aminotransferase family	-	-	2.6.1.102	ko:K13010	ko00520,map00520	-	R10460	RC00006,RC00781	ko00000,ko00001,ko01000,ko01005,ko01007	-	-	-	DegT_DnrJ_EryC1
k141_5256_12	857087.Metme_1158	2.27e-58	213.0	COG1132@1|root,COG1132@2|Bacteria,1MVJD@1224|Proteobacteria,1RQDM@1236|Gammaproteobacteria	1236|Gammaproteobacteria	V	(ABC) transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_membrane,ABC_tran
k141_5256_15	675814.VIC_005055	8.5e-182	513.0	COG0859@1|root,COG0859@2|Bacteria,1MXA2@1224|Proteobacteria,1RMBF@1236|Gammaproteobacteria,1XTBX@135623|Vibrionales	135623|Vibrionales	M	ADP-heptose--LPS heptosyltransferase II	rfaF	-	-	ko:K02843	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
k141_5256_16	675814.VIC_005056	3.11e-174	494.0	COG0859@1|root,COG0859@2|Bacteria,1NTHI@1224|Proteobacteria,1THBB@1236|Gammaproteobacteria,1XT14@135623|Vibrionales	135623|Vibrionales	M	Lipopolysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_9
k141_5256_17	55601.VANGNB10_cI2530	4.46e-111	338.0	COG3307@1|root,COG3307@2|Bacteria,1R8PC@1224|Proteobacteria,1RYYV@1236|Gammaproteobacteria,1XWTS@135623|Vibrionales	135623|Vibrionales	M	COG3307 Lipid A core - O-antigen ligase and related enzymes	waaL	-	-	ko:K02847	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01005,ko02000	9.B.67.4,9.B.67.5	-	-	Wzy_C
k141_5256_18	1056512.D515_03886	4.84e-116	349.0	COG0438@1|root,COG0438@2|Bacteria,1MU9C@1224|Proteobacteria,1RTS0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Glycosyl transferases group 1	lpcC	-	-	ko:K12989	-	-	-	-	ko00000,ko01000,ko01003,ko01005	-	GT4	-	Glyco_transf_4,Glycos_transf_1
k141_5256_19	243277.VC_0234	1.08e-135	390.0	COG3774@1|root,COG3774@2|Bacteria,1PTP7@1224|Proteobacteria,1S33R@1236|Gammaproteobacteria,1XVWC@135623|Vibrionales	135623|Vibrionales	M	COG3774 Mannosyltransferase OCH1 and related enzymes	-	-	-	-	-	-	-	-	-	-	-	-	Gly_transf_sug
k141_5256_20	55601.VANGNB10_cI2534	9.2e-172	494.0	COG1519@1|root,COG1519@2|Bacteria,1MU9F@1224|Proteobacteria,1RNBR@1236|Gammaproteobacteria,1XTJM@135623|Vibrionales	135623|Vibrionales	M	3-deoxy-D-manno-octulosonic-acid transferase	kdtA	-	2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15	ko:K02527	ko00540,ko01100,map00540,map01100	M00060,M00080	R04658,R05074,R09763	RC00009,RC00077,RC00247	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT30	-	Glycos_transf_1,Glycos_transf_N
k141_5256_21	1219080.VEZ01S_37_00340	1.25e-79	237.0	COG0561@1|root,COG0561@2|Bacteria,1RH4A@1224|Proteobacteria,1S61B@1236|Gammaproteobacteria,1XXK9@135623|Vibrionales	135623|Vibrionales	S	haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
k141_5256_22	345073.VC395_0263	9.1e-232	655.0	COG1208@1|root,COG1208@2|Bacteria,1P2A8@1224|Proteobacteria,1S213@1236|Gammaproteobacteria,1XWGK@135623|Vibrionales	135623|Vibrionales	JM	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_5256_23	345073.VC395_0262	2.55e-126	365.0	COG1209@1|root,COG1209@2|Bacteria,1RDR2@1224|Proteobacteria,1S4I7@1236|Gammaproteobacteria,1XV5S@135623|Vibrionales	135623|Vibrionales	M	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_5256_24	243277.VC_0229	7.03e-126	369.0	2CYX9@1|root,32T52@2|Bacteria,1RAI4@1224|Proteobacteria,1S35D@1236|Gammaproteobacteria,1XTF1@135623|Vibrionales	135623|Vibrionales	S	WavE lipopolysaccharide synthesis	-	-	-	-	-	-	-	-	-	-	-	-	WavE
k141_5256_25	264203.ZMO1301	2.62e-14	80.9	2CYX9@1|root,32T52@2|Bacteria,1RGNZ@1224|Proteobacteria	1224|Proteobacteria	S	WavE lipopolysaccharide synthesis	-	-	-	-	-	-	-	-	-	-	-	-	WavE
k141_5256_26	945543.VIBR0546_16341	4.46e-100	297.0	COG1718@1|root,COG1718@2|Bacteria,1QV96@1224|Proteobacteria,1T2AM@1236|Gammaproteobacteria,1Y343@135623|Vibrionales	135623|Vibrionales	H	Catalyzes the ATP-dependent phosphorylation of the 3- deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position	kdkA	-	2.7.1.166	ko:K11211	ko00540,map00540	-	R09767	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	Kdo
k141_5256_27	243277.VC_0225	2.33e-180	511.0	COG0859@1|root,COG0859@2|Bacteria,1MYZA@1224|Proteobacteria,1RR6K@1236|Gammaproteobacteria,1XSR4@135623|Vibrionales	135623|Vibrionales	M	COG0859 ADP-heptose LPS heptosyltransferase	-	-	-	ko:K12982	-	-	-	-	ko00000,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
k141_5256_28	55601.VANGNB10_cI2541	2.26e-155	439.0	COG0463@1|root,COG0463@2|Bacteria,1PVP4@1224|Proteobacteria,1RQUH@1236|Gammaproteobacteria,1XUS5@135623|Vibrionales	135623|Vibrionales	M	COG0463 Glycosyltransferases involved in cell wall biogenesis	-	-	-	ko:K12984	-	-	-	-	ko00000,ko01000,ko01003,ko01005,ko02000	4.D.1.3	GT2	-	Glycos_transf_2
k141_5256_29	945543.VIBR0546_16326	3.78e-177	502.0	COG0859@1|root,COG0859@2|Bacteria,1N5A1@1224|Proteobacteria,1RYYI@1236|Gammaproteobacteria,1XU8P@135623|Vibrionales	135623|Vibrionales	M	ADP-heptose-LPS heptosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_9
k141_5256_30	672.VV93_v1c02830	6.31e-89	263.0	COG0669@1|root,COG0669@2|Bacteria,1RD9F@1224|Proteobacteria,1S41J@1236|Gammaproteobacteria,1XUJI@135623|Vibrionales	135623|Vibrionales	H	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	GO:0003674,GO:0003824,GO:0004595,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
k141_5256_31	1219077.VAZ01S_022_00240	5.59e-135	389.0	COG0266@1|root,COG0266@2|Bacteria,1MVM5@1224|Proteobacteria,1RP3J@1236|Gammaproteobacteria,1XSAC@135623|Vibrionales	135623|Vibrionales	L	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates	fpg	GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
k141_5256_32	575788.VS_0185	1.4e-51	170.0	2EG7K@1|root,339ZF@2|Bacteria,1NHRB@1224|Proteobacteria,1SIIJ@1236|Gammaproteobacteria,1XX2H@135623|Vibrionales	135623|Vibrionales	-	-	VV10822	-	-	-	-	-	-	-	-	-	-	-	-
k141_893_2	272563.CD630_00190	3.03e-139	409.0	COG0707@1|root,COG0707@2|Bacteria,1UQ6A@1239|Firmicutes,248FR@186801|Clostridia,25QU0@186804|Peptostreptococcaceae	186801|Clostridia	M	Monogalactosyldiacylglycerol synthase	ugtP	-	2.4.1.315	ko:K03429	ko00561,ko01100,map00561,map01100	-	R02689,R04377	RC00005,RC00059	ko00000,ko00001,ko01000,ko01003	-	GT28	-	Glyco_tran_28_C,Glycos_transf_1,MGDG_synth
k141_893_3	1443125.Z962_02790	7.54e-108	327.0	COG0628@1|root,COG0628@2|Bacteria,1TQ84@1239|Firmicutes,248FS@186801|Clostridia,36EE4@31979|Clostridiaceae	186801|Clostridia	S	hmm pf01594	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
k141_893_4	1286171.EAL2_c00450	1.82e-29	106.0	COG0695@1|root,COG0695@2|Bacteria,1UF2R@1239|Firmicutes,25NBW@186801|Clostridia,25Z45@186806|Eubacteriaceae	186801|Clostridia	O	Glutaredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Glutaredoxin
k141_893_6	1121324.CLIT_16c00290	7.3e-103	304.0	COG2220@1|root,COG2220@2|Bacteria,1TQR1@1239|Firmicutes,249X0@186801|Clostridia	186801|Clostridia	S	Belongs to the UPF0173 family	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2,Lactamase_B_3
k141_893_7	1301100.HG529292_gene5164	1.81e-224	632.0	COG1757@1|root,COG1757@2|Bacteria,1TQ3B@1239|Firmicutes,248WN@186801|Clostridia,36FFK@31979|Clostridiaceae	186801|Clostridia	C	Na H antiporter	-	-	-	ko:K03315	-	-	-	-	ko00000,ko02000	2.A.35	-	-	Na_H_antiporter
k141_893_8	1211817.CCAT010000012_gene2760	1.88e-285	801.0	COG1032@1|root,COG1032@2|Bacteria,1TQ8X@1239|Firmicutes,248IW@186801|Clostridia,36DJY@31979|Clostridiaceae	186801|Clostridia	C	UPF0313 protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF3362,Radical_SAM,Radical_SAM_N
k141_4724_1	1121403.AUCV01000024_gene3439	9.77e-30	132.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42MXI@68525|delta/epsilon subdivisions,2WIX9@28221|Deltaproteobacteria,2MHVJ@213118|Desulfobacterales	28221|Deltaproteobacteria	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,Cache_3-Cache_2,HAMP,MCPsignal,PAS_3,dCache_1,sCache_2
k141_3702_2	521045.Kole_1187	1.31e-08	58.2	COG0477@1|root,COG2814@2|Bacteria,2GDQQ@200918|Thermotogae	200918|Thermotogae	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
k141_2577_1	55601.VANGNB10_cII0666c	5.98e-20	84.7	COG1776@1|root,COG1776@2|Bacteria,1RGHM@1224|Proteobacteria,1S5MS@1236|Gammaproteobacteria,1XY74@135623|Vibrionales	135623|Vibrionales	NT	Chemotaxis protein CheC, inhibitor of MCP methylation	-	-	-	ko:K03410	ko02030,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheC
k141_2577_2	55601.VANGNB10_cII0665c	2.43e-222	623.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,1RSDZ@1236|Gammaproteobacteria,1XUQA@135623|Vibrionales	135623|Vibrionales	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4
k141_2577_3	55601.VANGNB10_cII0662c	5.34e-185	530.0	COG3437@1|root,COG3437@2|Bacteria,1P1A3@1224|Proteobacteria,1S2RH@1236|Gammaproteobacteria,1XSG3@135623|Vibrionales	135623|Vibrionales	KT	COG3437 Response regulator containing a CheY-like receiver domain and an HD-GYP domain	-	-	-	-	-	-	-	-	-	-	-	-	HD_5,Response_reg
k141_2577_4	945550.VISI1226_11496	8.39e-61	195.0	COG0560@1|root,COG0560@2|Bacteria,1RA1A@1224|Proteobacteria,1S21J@1236|Gammaproteobacteria,1XSWS@135623|Vibrionales	135623|Vibrionales	E	COG0560 Phosphoserine phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	HAD
k141_1294_1	575788.VS_1626	2.57e-148	429.0	COG0420@1|root,COG0420@2|Bacteria,1MVV6@1224|Proteobacteria,1RP83@1236|Gammaproteobacteria,1XW3R@135623|Vibrionales	135623|Vibrionales	L	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity	sbcD	-	-	ko:K03547	-	-	-	-	ko00000,ko03400	-	-	-	Metallophos,SbcD_C
k141_3704_1	1449126.JQKL01000028_gene2619	8.91e-44	159.0	COG0348@1|root,COG1018@1|root,COG0348@2|Bacteria,COG1018@2|Bacteria,1UVGX@1239|Firmicutes,25MAU@186801|Clostridia,269U3@186813|unclassified Clostridiales	186801|Clostridia	C	Oxidoreductase NAD-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_6,NAD_binding_1
k141_896_1	1121403.AUCV01000018_gene3224	1.15e-122	353.0	COG0765@1|root,COG0765@2|Bacteria,1MX3E@1224|Proteobacteria,42P2J@68525|delta/epsilon subdivisions,2WJ0P@28221|Deltaproteobacteria,2MJ2M@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02029,ko:K10037	ko02010,map02010	M00227,M00236	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3,3.A.1.3.2	-	-	BPD_transp_1
k141_896_2	177439.DP1984	4.44e-51	168.0	COG1126@1|root,COG1126@2|Bacteria,1MU9Q@1224|Proteobacteria,42M0S@68525|delta/epsilon subdivisions,2WITR@28221|Deltaproteobacteria,2MICA@213118|Desulfobacterales	28221|Deltaproteobacteria	E	ABC transporter	-	-	3.6.3.21	ko:K02028,ko:K09972,ko:K10038	ko02010,map02010	M00227,M00232,M00236	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.3,3.A.1.3.17,3.A.1.3.18,3.A.1.3.2,3.A.1.3.7,3.A.1.3.8	-	-	ABC_tran
k141_4726_1	629265.PMA4326_03899	7.61e-16	87.4	COG1961@1|root,COG1961@2|Bacteria,1N6DV@1224|Proteobacteria,1RYWS@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	COG1961 Site-specific recombinases, DNA invertase Pin homologs	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
k141_2899_2	1484157.PSNIH2_00050	9.33e-189	540.0	COG1263@1|root,COG1264@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,1MVVJ@1224|Proteobacteria,1RRDA@1236|Gammaproteobacteria,3VXX5@53335|Pantoea	1236|Gammaproteobacteria	G	PTS system, sucrose-specific	scrA	-	2.7.1.211	ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	M00269	R00811	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.1.2.1,4.A.1.2.10,4.A.1.2.12,4.A.1.2.9	-	-	PTS_EIIB,PTS_EIIC
k141_2899_3	1219065.VPR01S_12_01290	1.7e-72	219.0	COG1943@1|root,COG1943@2|Bacteria,1RC43@1224|Proteobacteria,1S3FI@1236|Gammaproteobacteria,1XXJF@135623|Vibrionales	135623|Vibrionales	L	Transposase IS200 like	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
k141_643_1	1348635.BBJY01000008_gene1739	9.43e-80	249.0	COG0457@1|root,COG0457@2|Bacteria,1NFC8@1224|Proteobacteria,1RWMG@1236|Gammaproteobacteria,1XVGU@135623|Vibrionales	135623|Vibrionales	S	COG0457 FOG TPR repeat	VP2409	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_16,TPR_17,TPR_2,TPR_8
k141_643_2	1051646.VITU9109_21869	4.75e-125	367.0	COG2064@1|root,COG2064@2|Bacteria,1MWAZ@1224|Proteobacteria,1SZWZ@1236|Gammaproteobacteria,1XSF0@135623|Vibrionales	135623|Vibrionales	NU	COG2064 Flp pilus assembly protein TadC	VV2651	-	-	ko:K12511	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF
k141_643_3	945550.VISI1226_15756	2.05e-139	404.0	COG4965@1|root,COG4965@2|Bacteria,1MUXK@1224|Proteobacteria,1S1QN@1236|Gammaproteobacteria,1XVM8@135623|Vibrionales	135623|Vibrionales	U	COG4965 Flp pilus assembly protein TadB	-	-	-	ko:K12510	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF
k141_3706_2	316275.VSAL_I0638	6.82e-19	80.5	COG3630@1|root,COG3630@2|Bacteria,1NHYS@1224|Proteobacteria,1SG6X@1236|Gammaproteobacteria,1XYD5@135623|Vibrionales	135623|Vibrionales	C	Lyase and sodium transporter	oadG	GO:0003674,GO:0003824,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008150,GO:0008948,GO:0015672,GO:0016829,GO:0016830,GO:0016831,GO:0030001,GO:0051179,GO:0051234	4.1.1.3	ko:K01573	ko00620,ko01100,map00620,map01100	-	R00217	RC00040	ko00000,ko00001,ko01000,ko02000	3.B.1.1.1	-	-	OAD_gamma
k141_2060_18	575788.VS_2471	2.11e-70	219.0	COG3154@1|root,COG3154@2|Bacteria,1MZNC@1224|Proteobacteria,1S9BQ@1236|Gammaproteobacteria,1XUWR@135623|Vibrionales	135623|Vibrionales	I	lipid carrier protein	-	-	-	-	-	-	-	-	-	-	-	-	SCP2
k141_2060_20	945543.VIBR0546_02036	1.33e-298	837.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1XSRH@135623|Vibrionales	135623|Vibrionales	T	signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	VV2690	-	3.1.4.52	ko:K20965	ko05111,map05111	-	-	-	ko00000,ko00001,ko01000	-	-	-	EAL,GGDEF,PAS_4,PAS_8,PAS_9
k141_2060_21	675806.VII_003099	1.62e-202	565.0	COG0826@1|root,COG0826@2|Bacteria,1MUQG@1224|Proteobacteria,1RP6X@1236|Gammaproteobacteria,1XTKH@135623|Vibrionales	135623|Vibrionales	O	COG0826 Collagenase and related proteases	yhbU	-	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_U32
k141_2060_22	223926.28807446	4.23e-167	472.0	COG0826@1|root,COG0826@2|Bacteria,1MWFW@1224|Proteobacteria,1RMWM@1236|Gammaproteobacteria,1XT2K@135623|Vibrionales	135623|Vibrionales	O	COG0826 Collagenase and related proteases	yhbV	-	-	-	-	-	-	-	-	-	-	-	Peptidase_U32
k141_2060_23	945543.VIBR0546_02051	2.93e-143	423.0	COG0534@1|root,COG0534@2|Bacteria,1R4H5@1224|Proteobacteria,1RS0B@1236|Gammaproteobacteria,1XTRQ@135623|Vibrionales	135623|Vibrionales	V	Na driven multidrug efflux pump	vmrA	-	-	-	-	-	-	-	-	-	-	-	MatE
k141_2060_24	1280001.BAOA01000059_gene2271	2.72e-119	352.0	COG4785@1|root,COG4785@2|Bacteria,1N02Y@1224|Proteobacteria,1RP8P@1236|Gammaproteobacteria,1XT95@135623|Vibrionales	135623|Vibrionales	M	May be involved in cell division	nlpI	-	-	ko:K05803	-	-	-	-	ko00000	-	-	-	TPR_8
k141_2060_25	1116375.VEJY3_12670	0.0	1180.0	COG1185@1|root,COG1185@2|Bacteria,1MVB9@1224|Proteobacteria,1RNBF@1236|Gammaproteobacteria,1XUR3@135623|Vibrionales	135623|Vibrionales	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	GO:0003674,GO:0003824,GO:0004654,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
k141_2060_26	28152.DJ57_3554	1.15e-23	92.4	2EAVP@1|root,334X2@2|Bacteria,1N1GF@1224|Proteobacteria,1SBRU@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	immunity protein	imm	-	-	-	-	-	-	-	-	-	-	-	Colicin_Pyocin
k141_2060_31	675814.VIC_000545	2.8e-52	165.0	COG0184@1|root,COG0184@2|Bacteria,1MZ2W@1224|Proteobacteria,1S8U6@1236|Gammaproteobacteria,1XXSE@135623|Vibrionales	135623|Vibrionales	J	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome	rpsO	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
k141_2060_32	55601.VANGNB10_cI0544	1.51e-184	518.0	COG0130@1|root,COG0130@2|Bacteria,1MV0N@1224|Proteobacteria,1RMKP@1236|Gammaproteobacteria,1XSDN@135623|Vibrionales	135623|Vibrionales	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481	5.4.99.25	ko:K03177	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruB-C_2,TruB_C_2,TruB_N
k141_2060_33	243277.VC_0644	1e-68	210.0	COG0858@1|root,COG0858@2|Bacteria,1MZPE@1224|Proteobacteria,1S9AF@1236|Gammaproteobacteria,1XWW9@135623|Vibrionales	135623|Vibrionales	J	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA	rbfA	GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360	-	ko:K02834	-	-	-	-	ko00000,ko03009	-	-	-	RBFA
k141_2060_34	243277.VC_0643	0.0	1216.0	COG0532@1|root,COG0532@2|Bacteria,1MV26@1224|Proteobacteria,1RM9X@1236|Gammaproteobacteria,1XSU6@135623|Vibrionales	135623|Vibrionales	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,GTP_EFTU_D2,IF-2,IF2_N,IF2_assoc
k141_2060_35	1348635.BBJY01000008_gene1762	1.43e-310	852.0	COG0195@1|root,COG0195@2|Bacteria,1MWT7@1224|Proteobacteria,1RNQS@1236|Gammaproteobacteria,1XUW8@135623|Vibrionales	135623|Vibrionales	K	Participates in both transcription termination and antitermination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	HHH_5,KH_5,NusA_N
k141_2060_36	1219065.VPR01S_09_00910	7.49e-93	272.0	COG0779@1|root,COG0779@2|Bacteria,1RDP2@1224|Proteobacteria,1S3Y7@1236|Gammaproteobacteria,1XVAA@135623|Vibrionales	135623|Vibrionales	J	Required for maturation of 30S ribosomal subunits	rimP	GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576	-	ko:K09748	-	-	-	-	ko00000,ko03009	-	-	-	DUF150,DUF150_C
k141_2060_37	345073.VC395_0657	2.43e-48	157.0	COG1314@1|root,COG1314@2|Bacteria,1N8MF@1224|Proteobacteria,1SD3P@1236|Gammaproteobacteria,1XXUA@135623|Vibrionales	135623|Vibrionales	U	Preprotein translocase subunit SecG	secG	-	-	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecG
k141_2060_39	1187848.AJYQ01000127_gene631	4.82e-127	369.0	COG0294@1|root,COG0294@2|Bacteria,1MUIR@1224|Proteobacteria,1RM8G@1236|Gammaproteobacteria,1XTE1@135623|Vibrionales	135623|Vibrionales	H	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives	folP	-	2.5.1.15	ko:K00796	ko00790,ko01100,map00790,map01100	M00126,M00841	R03066,R03067	RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
k141_2060_40	1116375.VEJY3_12725	0.0	1120.0	COG0465@1|root,COG0465@2|Bacteria,1MU6J@1224|Proteobacteria,1RME8@1236|Gammaproteobacteria,1XT56@135623|Vibrionales	135623|Vibrionales	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
k141_2060_41	1238450.VIBNISOn1_210035	4.47e-136	386.0	COG0293@1|root,COG0293@2|Bacteria,1MW1C@1224|Proteobacteria,1RN5M@1236|Gammaproteobacteria,1XTF8@135623|Vibrionales	135623|Vibrionales	J	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit	ftsJ	-	2.1.1.166	ko:K02427	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ
k141_4790_1	675815.VOA_000732	1.29e-62	211.0	COG0457@1|root,COG0457@2|Bacteria,1RDRI@1224|Proteobacteria,1S3PB@1236|Gammaproteobacteria,1XTIH@135623|Vibrionales	135623|Vibrionales	S	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_12
k141_4790_2	945543.VIBR0546_18667	9.73e-139	414.0	COG2199@1|root,COG2199@2|Bacteria,1QWGR@1224|Proteobacteria,1T3HC@1236|Gammaproteobacteria,1Y351@135623|Vibrionales	135623|Vibrionales	T	GGDEF family	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
k141_4790_3	945550.VISI1226_02892	4.54e-277	763.0	COG1611@1|root,COG1611@2|Bacteria,1MVQJ@1224|Proteobacteria,1RQHX@1236|Gammaproteobacteria,1XVEP@135623|Vibrionales	135623|Vibrionales	S	Rossmann fold nucleotide-binding protein	ygdH	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	DUF3412,DUF4478,Lysine_decarbox
k141_4790_4	1238450.VIBNISOn1_820065	1.56e-148	421.0	COG0258@1|root,COG0258@2|Bacteria,1MX9Y@1224|Proteobacteria,1RQZE@1236|Gammaproteobacteria,1XTDZ@135623|Vibrionales	135623|Vibrionales	L	Has flap endonuclease activity. During DNA replication, flap endonucleases cleave the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment	xni	GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0006139,GO:0006259,GO:0006281,GO:0006308,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016787,GO:0016788,GO:0019439,GO:0033554,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:1901360,GO:1901361,GO:1901575	-	ko:K01146	-	-	-	-	ko00000	-	-	-	5_3_exonuc,5_3_exonuc_N
k141_90_1	1353529.M899_0938	8.97e-126	374.0	COG3634@1|root,COG3634@2|Bacteria,1MUKD@1224|Proteobacteria,42P04@68525|delta/epsilon subdivisions,2MTQR@213481|Bdellovibrionales,2WMFA@28221|Deltaproteobacteria	213481|Bdellovibrionales	O	Pyridine nucleotide-disulphide oxidoreductase	ahpF	-	-	ko:K03387	-	-	-	-	ko00000,ko01000	-	-	-	Pyr_redox_2,Thioredoxin_3
k141_90_2	388413.ALPR1_01340	1.5e-95	293.0	COG0583@1|root,COG0583@2|Bacteria,4NGZ5@976|Bacteroidetes,47JGK@768503|Cytophagia	976|Bacteroidetes	K	Bacterial regulatory helix-turn-helix protein, lysR family	oxyR	-	-	ko:K04761	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_1,LysR_substrate
k141_1405_1	439235.Dalk_1888	2.38e-17	78.2	COG0203@1|root,COG0203@2|Bacteria,1RCWN@1224|Proteobacteria,42SBD@68525|delta/epsilon subdivisions,2WP9P@28221|Deltaproteobacteria,2MKCX@213118|Desulfobacterales	28221|Deltaproteobacteria	J	PFAM ribosomal protein L17	rplQ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02879	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L17
k141_1405_2	1121405.dsmv_3564	1.71e-150	434.0	COG0202@1|root,COG0202@2|Bacteria,1MU75@1224|Proteobacteria,42MIX@68525|delta/epsilon subdivisions,2WJ5K@28221|Deltaproteobacteria,2MI89@213118|Desulfobacterales	28221|Deltaproteobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
k141_1405_3	1304885.AUEY01000001_gene3224	1.01e-98	291.0	COG0522@1|root,COG0522@2|Bacteria,1MW0U@1224|Proteobacteria,42M5X@68525|delta/epsilon subdivisions,2WJGN@28221|Deltaproteobacteria,2MIGC@213118|Desulfobacterales	28221|Deltaproteobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
k141_1405_4	981383.AEWH01000035_gene849	2.51e-60	188.0	COG0100@1|root,COG0100@2|Bacteria,1V3IK@1239|Firmicutes,4HH2T@91061|Bacilli	91061|Bacilli	J	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome	rpsK	GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
k141_1405_5	1519464.HY22_03250	1.86e-48	158.0	COG0099@1|root,COG0099@2|Bacteria,1FE1B@1090|Chlorobi	1090|Chlorobi	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	rpsM	-	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
k141_1405_6	1444310.JANV01000115_gene4517	3.66e-35	121.0	COG0361@1|root,COG0361@2|Bacteria,1V9ZK@1239|Firmicutes,4HKF4@91061|Bacilli,1ZHWN@1386|Bacillus	91061|Bacilli	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009986,GO:0030246,GO:0030247,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:2001065	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
k141_1405_7	177437.HRM2_36060	2.74e-218	613.0	COG0201@1|root,COG0201@2|Bacteria,1MVU7@1224|Proteobacteria,42MGM@68525|delta/epsilon subdivisions,2WIZ7@28221|Deltaproteobacteria,2MHM9@213118|Desulfobacterales	28221|Deltaproteobacteria	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	-	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
k141_1405_8	340099.Teth39_0392	1.16e-41	142.0	COG0200@1|root,COG0200@2|Bacteria,1V3KE@1239|Firmicutes,24HAJ@186801|Clostridia,42G84@68295|Thermoanaerobacterales	186801|Clostridia	J	Binds to the 23S rRNA	rplO	-	-	ko:K02876	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27A
k141_1405_9	1121405.dsmv_3572	1.63e-21	85.5	COG1841@1|root,COG1841@2|Bacteria,1PU2T@1224|Proteobacteria,42WNP@68525|delta/epsilon subdivisions,2WRZZ@28221|Deltaproteobacteria,2MM1B@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Ribosomal protein L30p/L7e	rpmD	-	-	ko:K02907	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L30
k141_1405_10	985762.SAGN_08900	1.61e-64	202.0	COG0098@1|root,COG0098@2|Bacteria,1V1B1@1239|Firmicutes,4HFN4@91061|Bacilli,4GXWC@90964|Staphylococcaceae	91061|Bacilli	J	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body	rpsE	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02988	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S5,Ribosomal_S5_C
k141_1405_11	177437.HRM2_36100	2.71e-40	137.0	COG0256@1|root,COG0256@2|Bacteria,1RGY7@1224|Proteobacteria,42TIT@68525|delta/epsilon subdivisions,2WQ8U@28221|Deltaproteobacteria,2MKF7@213118|Desulfobacterales	28221|Deltaproteobacteria	J	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance	rplR	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904	-	ko:K02881	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L18p
k141_1405_12	1304885.AUEY01000001_gene3233	5.33e-63	199.0	COG0097@1|root,COG0097@2|Bacteria,1R9YZ@1224|Proteobacteria,42NSE@68525|delta/epsilon subdivisions,2WN9B@28221|Deltaproteobacteria,2MIP4@213118|Desulfobacterales	28221|Deltaproteobacteria	J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center	rplF	GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02933	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L6
k141_1405_13	1304885.AUEY01000001_gene3234	1.38e-61	192.0	COG0096@1|root,COG0096@2|Bacteria,1RDG3@1224|Proteobacteria,42SF6@68525|delta/epsilon subdivisions,2WPDP@28221|Deltaproteobacteria,2MJZV@213118|Desulfobacterales	28221|Deltaproteobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit	rpsH	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02994	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S8
k141_1405_14	479434.Sthe_1049	1.41e-26	98.2	COG0199@1|root,COG0199@2|Bacteria,2G74J@200795|Chloroflexi	200795|Chloroflexi	J	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site	rpsN	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02954	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S14
k141_1405_15	96561.Dole_0720	2.99e-94	278.0	COG0094@1|root,COG0094@2|Bacteria,1MUU9@1224|Proteobacteria,42QS6@68525|delta/epsilon subdivisions,2WMPD@28221|Deltaproteobacteria,2MJFM@213118|Desulfobacterales	28221|Deltaproteobacteria	J	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits	rplE	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02931	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L5,Ribosomal_L5_C
k141_1405_16	1304885.AUEY01000001_gene3236	2.24e-44	146.0	COG0198@1|root,COG0198@2|Bacteria,1MZQD@1224|Proteobacteria,42TGC@68525|delta/epsilon subdivisions,2WQ2G@28221|Deltaproteobacteria,2MKGD@213118|Desulfobacterales	28221|Deltaproteobacteria	J	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit	rplX	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02895	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KOW,ribosomal_L24
k141_1405_17	96561.Dole_0718	3.72e-61	190.0	COG0093@1|root,COG0093@2|Bacteria,1RCWZ@1224|Proteobacteria,42RHR@68525|delta/epsilon subdivisions,2WNEK@28221|Deltaproteobacteria,2MJSK@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome	rplN	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904	-	ko:K02874	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L14
k141_1405_18	1121405.dsmv_3580	5.38e-37	126.0	COG0186@1|root,COG0186@2|Bacteria,1MZIK@1224|Proteobacteria,42TNS@68525|delta/epsilon subdivisions,2WR6G@28221|Deltaproteobacteria,2MKWR@213118|Desulfobacterales	28221|Deltaproteobacteria	J	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA	rpsQ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02961	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S17
k141_1405_19	243231.GSU2849	2.93e-13	64.7	COG0255@1|root,COG0255@2|Bacteria,1Q1R3@1224|Proteobacteria,42WYX@68525|delta/epsilon subdivisions,2WSTS@28221|Deltaproteobacteria,43VXF@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	structural constituent of ribosome	rpmC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02904	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L29
k141_1405_20	1304885.AUEY01000001_gene3240	2.49e-63	196.0	COG0197@1|root,COG0197@2|Bacteria,1RA0Z@1224|Proteobacteria,42QW5@68525|delta/epsilon subdivisions,2WP71@28221|Deltaproteobacteria,2MJKH@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs	rplP	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904	-	ko:K02878	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L16
k141_1405_21	1304885.AUEY01000001_gene3241	1.15e-109	320.0	COG0092@1|root,COG0092@2|Bacteria,1MUAI@1224|Proteobacteria,42N5W@68525|delta/epsilon subdivisions,2WIU3@28221|Deltaproteobacteria,2MIQ4@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation	rpsC	GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02982	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KH_2,Ribosomal_S3_C
k141_1054_85	1449126.JQKL01000051_gene3158	2.97e-42	155.0	COG3500@1|root,COG3500@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K06905	-	-	-	-	ko00000	-	-	-	-
k141_1054_86	1123239.KB898628_gene3244	4.49e-27	105.0	COG1652@1|root,COG1652@2|Bacteria,1VE0Z@1239|Firmicutes,4IUU2@91061|Bacilli	91061|Bacilli	S	LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_1054_89	1401067.HMPREF0872_00250	1.26e-15	74.7	2CBYI@1|root,333M7@2|Bacteria	2|Bacteria	S	Phage XkdN-like tail assembly chaperone protein, TAC	-	-	-	-	-	-	-	-	-	-	-	-	Phage_TAC_5
k141_1054_90	1294142.CINTURNW_0298	4.76e-39	136.0	2CCC9@1|root,32JA4@2|Bacteria,1V9J9@1239|Firmicutes,25HMV@186801|Clostridia,36UCV@31979|Clostridiaceae	186801|Clostridia	S	Phage tail tube protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF2001
k141_1054_91	1449126.JQKL01000051_gene3164	8.1e-128	377.0	28ISD@1|root,2Z8RJ@2|Bacteria,1TQJ7@1239|Firmicutes,2499A@186801|Clostridia,26API@186813|unclassified Clostridiales	186801|Clostridia	S	Phage tail sheath protein subtilisin-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Phage_sheath_1,Phage_sheath_1C
k141_436_2	1499967.BAYZ01000122_gene3376	2.74e-48	174.0	COG1337@1|root,COG1337@2|Bacteria,2NRVQ@2323|unclassified Bacteria	2|Bacteria	L	RAMP superfamily	-	-	-	-	-	-	-	-	-	-	-	-	RAMPs
k141_2086_1	521000.PROVRETT_07517	4.98e-16	79.0	COG0446@1|root,COG0446@2|Bacteria,1R6RY@1224|Proteobacteria,1RR2B@1236|Gammaproteobacteria,3Z7KT@586|Providencia	1236|Gammaproteobacteria	C	Pyridine nucleotide-disulfide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2
k141_2086_2	1123319.AUBE01000010_gene4290	7.52e-14	70.5	COG4977@1|root,COG4977@2|Bacteria,2GM0M@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain	-	-	-	-	-	-	-	-	-	-	-	-	DJ-1_PfpI,HTH_18
k141_4474_2	1396858.Q666_12070	3.39e-78	245.0	2EWUC@1|root,33Q5X@2|Bacteria,1NQW8@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_437_1	223926.28808899	6.2e-32	128.0	COG1629@1|root,COG4771@2|Bacteria,1MX42@1224|Proteobacteria,1RQ2K@1236|Gammaproteobacteria,1XT4R@135623|Vibrionales	135623|Vibrionales	P	COG1629 Outer membrane receptor proteins, mostly Fe transport	vctA	-	-	ko:K16087	-	-	-	-	ko00000,ko02000	1.B.14.2	-	-	Plug,TonB_dep_Rec
k141_128_2	945543.VIBR0546_07512	0.0	1304.0	COG1025@1|root,COG1025@2|Bacteria,1QTVC@1224|Proteobacteria,1T1IG@1236|Gammaproteobacteria,1XT1Q@135623|Vibrionales	135623|Vibrionales	O	Belongs to the peptidase M16 family	ptrA	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C,Peptidase_M16_M
k141_128_3	1280001.BAOA01000009_gene4135	1.37e-57	183.0	COG2062@1|root,COG2062@2|Bacteria,1NAAE@1224|Proteobacteria,1SAT1@1236|Gammaproteobacteria,1XXBT@135623|Vibrionales	135623|Vibrionales	T	Phosphohistidine phosphatase sixA	sixA	-	-	ko:K08296	-	-	-	-	ko00000,ko01000	-	-	-	His_Phos_1
k141_3121_1	198628.Dda3937_04312	5.81e-67	232.0	COG3209@1|root,COG3209@2|Bacteria,1MVV1@1224|Proteobacteria,1SKYM@1236|Gammaproteobacteria,2JEQ6@204037|Dickeya	1236|Gammaproteobacteria	M	TIGRFAM YD repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF4150,PAAR_motif,RHS,RHS_repeat,Tox-HNH-EHHH
k141_3121_3	1348635.BBJY01000001_gene2528	7.57e-132	389.0	COG0701@1|root,COG0701@2|Bacteria,1MUN8@1224|Proteobacteria,1RSPM@1236|Gammaproteobacteria,1XSCM@135623|Vibrionales	135623|Vibrionales	S	Predicted permease	-	-	-	ko:K07089	-	-	-	-	ko00000	-	-	-	ArsP_1
k141_3121_4	1116375.VEJY3_18346	3.02e-227	633.0	COG0477@1|root,COG2814@2|Bacteria,1MWFH@1224|Proteobacteria,1RPAT@1236|Gammaproteobacteria,1XTE4@135623|Vibrionales	1236|Gammaproteobacteria	EGP	of the major facilitator superfamily	ynfM	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K08224	-	-	-	-	ko00000,ko02000	2.A.1.36	-	-	MFS_1,Sugar_tr
k141_3502_1	643473.KB235930_gene546	8.07e-07	50.1	COG2319@1|root,COG2319@2|Bacteria,1G9VI@1117|Cyanobacteria,1HPKF@1161|Nostocales	1117|Cyanobacteria	S	Wd-40 repeat	-	-	-	-	-	-	-	-	-	-	-	-	Pilin_GH
k141_3502_3	177439.DP2053	5.93e-47	152.0	COG0599@1|root,COG0599@2|Bacteria,1PZQH@1224|Proteobacteria,42XZK@68525|delta/epsilon subdivisions,2WT47@28221|Deltaproteobacteria,2MPEA@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Carboxymuconolactone decarboxylase family	-	-	-	-	-	-	-	-	-	-	-	-	CMD
k141_1055_1	243277.VC_1414	1.41e-275	764.0	COG2317@1|root,COG2317@2|Bacteria,1MW7T@1224|Proteobacteria,1RQM5@1236|Gammaproteobacteria,1XTZ9@135623|Vibrionales	135623|Vibrionales	E	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues	-	-	3.4.17.19	ko:K01299	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M32
k141_3503_1	96561.Dole_0789	1.69e-68	219.0	COG3577@1|root,COG3577@2|Bacteria,1RIR3@1224|Proteobacteria,42UXY@68525|delta/epsilon subdivisions,2WR2W@28221|Deltaproteobacteria,2MM4V@213118|Desulfobacterales	28221|Deltaproteobacteria	L	gag-polyprotein putative aspartyl protease	-	-	-	-	-	-	-	-	-	-	-	-	Asp_protease_2,DUF4124,gag-asp_proteas
k141_1764_1	246194.CHY_1871	7.7e-64	200.0	COG2316@1|root,COG2316@2|Bacteria,1TSF7@1239|Firmicutes,24A1B@186801|Clostridia,42FYS@68295|Thermoanaerobacterales	186801|Clostridia	S	PFAM Metal-dependent phosphohydrolase, HD	-	-	-	-	-	-	-	-	-	-	-	-	HD
k141_1764_2	1121451.DESAM_21577	2.19e-69	221.0	COG0834@1|root,COG0834@2|Bacteria,1N6R7@1224|Proteobacteria,435TF@68525|delta/epsilon subdivisions,2X08J@28221|Deltaproteobacteria,2MB87@213115|Desulfovibrionales	28221|Deltaproteobacteria	ET	PFAM Extracellular solute-binding protein, family 3	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
k141_1764_3	879212.DespoDRAFT_00122	1.95e-180	517.0	COG0141@1|root,COG0141@2|Bacteria,1MUUF@1224|Proteobacteria,42M3R@68525|delta/epsilon subdivisions,2WJGT@28221|Deltaproteobacteria,2MICP@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine	hisD	GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.23	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01158,R01163,R03012	RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000	-	-	-	Histidinol_dh
k141_1764_4	96561.Dole_3221	7.32e-150	434.0	COG1932@1|root,COG1932@2|Bacteria,1MUB5@1224|Proteobacteria,42MEN@68525|delta/epsilon subdivisions,2WIYF@28221|Deltaproteobacteria,2MIJH@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine	serC	-	2.6.1.52	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	M00020,M00124	R04173,R05085	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
k141_1764_5	443254.Marpi_2001	1.28e-57	184.0	COG1225@1|root,COG1225@2|Bacteria,2GD2E@200918|Thermotogae	200918|Thermotogae	O	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA,Nitroreductase
k141_1764_6	484770.UFO1_1066	6.7e-28	111.0	COG1280@1|root,COG1280@2|Bacteria,1V1T0@1239|Firmicutes,4H4FC@909932|Negativicutes	909932|Negativicutes	E	LysE type translocator	-	-	-	-	-	-	-	-	-	-	-	-	LysE
k141_1056_1	1120963.KB894491_gene976	1.48e-13	73.6	COG0834@1|root,COG0834@2|Bacteria,1RIEF@1224|Proteobacteria,1S7RQ@1236|Gammaproteobacteria,2Q59Z@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	ET	Bacterial extracellular solute-binding proteins, family 3	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
k141_1056_2	526222.Desal_2052	2.94e-12	67.0	COG5438@1|root,COG5438@2|Bacteria,1MYCQ@1224|Proteobacteria,42PF1@68525|delta/epsilon subdivisions,2WM9H@28221|Deltaproteobacteria,2MEMU@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	YibE/F-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YibE_F
k141_1765_1	1121405.dsmv_1317	2.61e-112	329.0	COG0708@1|root,COG0708@2|Bacteria,1MVII@1224|Proteobacteria,42NY7@68525|delta/epsilon subdivisions,2WIXK@28221|Deltaproteobacteria,2MIF2@213118|Desulfobacterales	28221|Deltaproteobacteria	L	PFAM Endonuclease Exonuclease phosphatase	exoA	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
k141_2090_2	1220534.B655_2427	5.87e-28	119.0	COG0784@1|root,COG2202@1|root,COG2203@1|root,arCOG04001@1|root,arCOG02361@2157|Archaea,arCOG04001@2157|Archaea,arCOG06537@2157|Archaea,arCOG06918@2157|Archaea	2157|Archaea	T	Pas domain	-	-	-	-	-	-	-	-	-	-	-	-	BAT,GAF_2,GAF_3,HATPase_c,HTH_10,HisKA,HisKA_2,PAS,PAS_3,PAS_4,PAS_8,PAS_9,PocR,Response_reg
k141_438_3	1121434.AULY01000007_gene1565	4.73e-122	377.0	COG0145@1|root,COG0145@2|Bacteria,1MU2Y@1224|Proteobacteria,42MSS@68525|delta/epsilon subdivisions,2WIN2@28221|Deltaproteobacteria,2M99D@213115|Desulfovibrionales	28221|Deltaproteobacteria	EQ	Hydantoinaseoxoprolinase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF1638,Hydant_A_N,Hydantoinase_A
k141_438_4	536227.CcarbDRAFT_1817	2.74e-09	64.7	COG1146@1|root,COG1146@2|Bacteria,1UZ6D@1239|Firmicutes,24Q6M@186801|Clostridia,36QG6@31979|Clostridiaceae	186801|Clostridia	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_10
k141_1766_1	1236542.BALM01000001_gene19	2.92e-48	164.0	COG0715@1|root,COG0715@2|Bacteria,1MVRA@1224|Proteobacteria,1RNG0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components	thiY	-	-	ko:K15598	ko02010,map02010	M00442	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.17.3,3.A.1.17.6	-	-	NMT1
k141_1766_2	298386.PBPRA2337	2.13e-69	217.0	COG2145@1|root,COG2145@2|Bacteria,1MVES@1224|Proteobacteria,1RRAE@1236|Gammaproteobacteria,1XSM9@135623|Vibrionales	135623|Vibrionales	H	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)	thiM	-	2.7.1.50	ko:K00878	ko00730,ko01100,map00730,map01100	M00127	R04448	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HK
k141_1173_2	1121403.AUCV01000057_gene3058	6.63e-33	119.0	COG1846@1|root,COG1846@2|Bacteria,1NA1D@1224|Proteobacteria	1224|Proteobacteria	K	MarR family	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
k141_193_1	269797.Mbar_A2399	2.8e-38	142.0	COG0500@1|root,arCOG03411@2157|Archaea,2XWTI@28890|Euryarchaeota,2NAD9@224756|Methanomicrobia	224756|Methanomicrobia	Q	Dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	Dimerisation2,Methyltransf_2
k141_5175_1	1123261.AXDW01000007_gene2152	1.02e-18	90.9	COG1629@1|root,COG4771@2|Bacteria,1MWKN@1224|Proteobacteria,1RMM6@1236|Gammaproteobacteria,1X2Y6@135614|Xanthomonadales	135614|Xanthomonadales	P	TonB-dependent Receptor Plug Domain	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
k141_2804_1	1232437.KL662013_gene1354	9.79e-73	237.0	COG0763@1|root,COG0763@2|Bacteria,1MVBI@1224|Proteobacteria,42P35@68525|delta/epsilon subdivisions,2WJFA@28221|Deltaproteobacteria,2MIFD@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxB	GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	2.4.1.182	ko:K00748	ko00540,ko01100,map00540,map01100	M00060	R04606	RC00005,RC00059	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT19	-	LpxB
k141_2804_2	1304885.AUEY01000030_gene2421	3.84e-83	258.0	COG3494@1|root,COG3494@2|Bacteria,1MWTH@1224|Proteobacteria,42P40@68525|delta/epsilon subdivisions,2WK7K@28221|Deltaproteobacteria,2MHT1@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF1009)	-	-	-	ko:K09949	-	-	-	-	ko00000	-	-	-	DUF1009
k141_2804_3	1121405.dsmv_3142	1.47e-80	249.0	COG1043@1|root,COG1043@2|Bacteria,1MUHQ@1224|Proteobacteria,42NPG@68525|delta/epsilon subdivisions,2WJVP@28221|Deltaproteobacteria,2MI18@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxA	-	2.3.1.129	ko:K00677	ko00540,ko01100,ko01503,map00540,map01100,map01503	M00060	R04567	RC00039,RC00055	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Acetyltransf_11,Hexapep
k141_2804_4	156889.Mmc1_1850	4.95e-47	156.0	COG0764@1|root,COG0764@2|Bacteria,1RH2T@1224|Proteobacteria,2U7G4@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs	fabZ	-	4.2.1.59	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121	RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FabA
k141_2804_5	1232437.KL662013_gene1357	4.7e-53	185.0	COG1044@1|root,COG1044@2|Bacteria,1MUX6@1224|Proteobacteria,42M4X@68525|delta/epsilon subdivisions,2WJJY@28221|Deltaproteobacteria,2MI3C@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxD	GO:0003674,GO:0003824,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	2.3.1.191	ko:K02536	ko00540,ko01100,map00540,map01100	M00060	R04550	RC00039,RC00166	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hexapep,Hexapep_2,LpxD
k141_2804_6	1232437.KL662013_gene1358	4.35e-33	123.0	COG2825@1|root,COG2825@2|Bacteria,1MZVJ@1224|Proteobacteria,42VH3@68525|delta/epsilon subdivisions,2WP6K@28221|Deltaproteobacteria,2MK60@213118|Desulfobacterales	28221|Deltaproteobacteria	M	PFAM Outer membrane	-	-	-	ko:K06142	-	-	-	-	ko00000	-	-	-	OmpH
k141_2804_7	1304885.AUEY01000030_gene2426	2.03e-251	723.0	COG4775@1|root,COG4775@2|Bacteria,1MU0D@1224|Proteobacteria,42MMA@68525|delta/epsilon subdivisions,2WIZB@28221|Deltaproteobacteria,2MIBK@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamA	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
k141_194_1	1121447.JONL01000006_gene12	2.19e-109	334.0	COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,42MV2@68525|delta/epsilon subdivisions,2WJ7U@28221|Deltaproteobacteria,2M839@213115|Desulfovibrionales	28221|Deltaproteobacteria	H	TIGRFAM Acetolactate synthase, large subunit, biosynthetic	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
k141_3529_1	1139219.I569_00174	3.85e-19	85.1	COG2153@1|root,COG2153@2|Bacteria,1VA2J@1239|Firmicutes,4HKF5@91061|Bacilli,4B39R@81852|Enterococcaceae	91061|Bacilli	S	Acetyltransferase (GNAT) domain	yjcF	GO:0003674,GO:0003824,GO:0016740,GO:0016746,GO:0016747	-	-	-	-	-	-	-	-	-	-	Acetyltransf_10
k141_2446_1	1122931.AUAE01000014_gene1958	6.2e-40	140.0	COG0652@1|root,COG0652@2|Bacteria,4NGT6@976|Bacteroidetes,2FMZ6@200643|Bacteroidia,22XHA@171551|Porphyromonadaceae	976|Bacteroidetes	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	ppiA	-	5.2.1.8	ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Pro_isomerase
k141_4910_1	908338.HMPREF9286_1584	1.86e-21	97.4	COG2603@1|root,COG2603@2|Bacteria,1TQ8T@1239|Firmicutes,24AM7@186801|Clostridia,22I8N@1570339|Peptoniphilaceae	186801|Clostridia	S	tRNA 2-selenouridine synthase	selU	-	-	ko:K06917	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Rhodanese
k141_4910_2	1121396.KB893092_gene3365	4.56e-116	350.0	COG0459@1|root,COG0459@2|Bacteria,1MURR@1224|Proteobacteria,42M52@68525|delta/epsilon subdivisions,2WIRK@28221|Deltaproteobacteria,2MHPV@213118|Desulfobacterales	28221|Deltaproteobacteria	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	-	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
k141_2805_1	1207058.L53_04315	5.04e-18	94.0	COG1629@1|root,COG4771@2|Bacteria,1R533@1224|Proteobacteria,2TVP0@28211|Alphaproteobacteria,43Z9M@69657|Hyphomonadaceae	28211|Alphaproteobacteria	P	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
k141_1174_1	207559.Dde_3039	0.0	918.0	COG1882@1|root,COG1882@2|Bacteria,1MWBF@1224|Proteobacteria,42M5J@68525|delta/epsilon subdivisions,2WJAK@28221|Deltaproteobacteria,2M9FS@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	Glycine radical	cutC	GO:0001505,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006576,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009308,GO:0009310,GO:0009987,GO:0016829,GO:0016840,GO:0019695,GO:0033265,GO:0034641,GO:0042133,GO:0042135,GO:0042165,GO:0042402,GO:0042426,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0044106,GO:0044237,GO:0044248,GO:0046983,GO:0065007,GO:0065008,GO:0070405,GO:0071704,GO:0097164,GO:1901564,GO:1901565,GO:1901575	4.3.99.4	ko:K20038	-	-	-	-	ko00000,ko01000	-	-	-	Gly_radical,PFL-like
k141_1175_1	55601.VANGNB10_cII0678	2.1e-66	223.0	COG2199@1|root,COG2199@2|Bacteria,1R5EK@1224|Proteobacteria,1SNTR@1236|Gammaproteobacteria,1XUDU@135623|Vibrionales	135623|Vibrionales	T	Sensory box GGDEF family	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS_9,dCache_1
k141_2465_1	945543.VIBR0546_21030	7.35e-134	402.0	COG1199@1|root,COG1199@2|Bacteria,1MVCU@1224|Proteobacteria,1RMNX@1236|Gammaproteobacteria,1XSN4@135623|Vibrionales	135623|Vibrionales	KL	COG1199 Rad3-related DNA helicases	dinG	-	3.6.4.12	ko:K03722	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD_2,Helicase_C_2,ResIII
k141_2465_2	1280001.BAOA01000060_gene2353	5.11e-24	100.0	COG1199@1|root,COG1199@2|Bacteria,1MVCU@1224|Proteobacteria,1RMNX@1236|Gammaproteobacteria,1XSN4@135623|Vibrionales	135623|Vibrionales	KL	COG1199 Rad3-related DNA helicases	dinG	-	3.6.4.12	ko:K03722	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD_2,Helicase_C_2,ResIII
k141_1483_1	525897.Dbac_1915	1.7e-146	449.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MQ0@68525|delta/epsilon subdivisions,2WJ2A@28221|Deltaproteobacteria,2MG2S@213115|Desulfovibrionales	28221|Deltaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k141_1483_2	283942.IL0466	2.24e-25	105.0	COG0845@1|root,COG0845@2|Bacteria,1R4JA@1224|Proteobacteria,1RPS5@1236|Gammaproteobacteria,2QFRN@267893|Idiomarinaceae	1236|Gammaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	ttgA	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
k141_2466_1	6500.XP_005094527.1	6.05e-05	53.1	COG4249@1|root,2QUZM@2759|Eukaryota,38EAM@33154|Opisthokonta,3BFCX@33208|Metazoa,3CRYX@33213|Bilateria	33208|Metazoa	T	lymphoid tissue lymphoma translocation	MALT1	GO:0001650,GO:0001775,GO:0001817,GO:0001819,GO:0001923,GO:0001932,GO:0001934,GO:0002020,GO:0002218,GO:0002220,GO:0002223,GO:0002237,GO:0002253,GO:0002335,GO:0002376,GO:0002429,GO:0002520,GO:0002521,GO:0002682,GO:0002684,GO:0002694,GO:0002696,GO:0002697,GO:0002699,GO:0002700,GO:0002702,GO:0002703,GO:0002705,GO:0002706,GO:0002708,GO:0002709,GO:0002711,GO:0002718,GO:0002720,GO:0002724,GO:0002726,GO:0002757,GO:0002758,GO:0002764,GO:0002768,GO:0002819,GO:0002821,GO:0002822,GO:0002824,GO:0003674,GO:0003824,GO:0004175,GO:0004197,GO:0004842,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005730,GO:0005737,GO:0005829,GO:0006355,GO:0006464,GO:0006508,GO:0006807,GO:0006810,GO:0006913,GO:0006950,GO:0006952,GO:0006955,GO:0007154,GO:0007165,GO:0007166,GO:0007250,GO:0007275,GO:0008150,GO:0008152,GO:0008233,GO:0008234,GO:0008283,GO:0009605,GO:0009607,GO:0009617,GO:0009620,GO:0009889,GO:0009893,GO:0009966,GO:0009967,GO:0009987,GO:0010033,GO:0010468,GO:0010556,GO:0010562,GO:0010604,GO:0010646,GO:0010647,GO:0010941,GO:0016043,GO:0016567,GO:0016740,GO:0016787,GO:0019219,GO:0019220,GO:0019222,GO:0019538,GO:0019787,GO:0019899,GO:0022407,GO:0022409,GO:0022607,GO:0023051,GO:0023052,GO:0023056,GO:0030097,GO:0030098,GO:0030154,GO:0030155,GO:0030183,GO:0031323,GO:0031325,GO:0031326,GO:0031347,GO:0031349,GO:0031396,GO:0031398,GO:0031399,GO:0031401,GO:0031974,GO:0031981,GO:0032147,GO:0032268,GO:0032270,GO:0032446,GO:0032449,GO:0032501,GO:0032502,GO:0032663,GO:0032743,GO:0032943,GO:0032991,GO:0033674,GO:0035556,GO:0036211,GO:0038061,GO:0038093,GO:0038095,GO:0042098,GO:0042110,GO:0042113,GO:0042221,GO:0042325,GO:0042327,GO:0042802,GO:0042981,GO:0043066,GO:0043067,GO:0043069,GO:0043085,GO:0043170,GO:0043207,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043370,GO:0043372,GO:0043412,GO:0043549,GO:0043621,GO:0043933,GO:0044085,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044452,GO:0044464,GO:0045087,GO:0045088,GO:0045089,GO:0045321,GO:0045580,GO:0045582,GO:0045595,GO:0045597,GO:0045619,GO:0045621,GO:0045622,GO:0045624,GO:0045785,GO:0045859,GO:0045860,GO:0045937,GO:0046634,GO:0046635,GO:0046637,GO:0046638,GO:0046649,GO:0046651,GO:0046907,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048534,GO:0048583,GO:0048584,GO:0048731,GO:0048856,GO:0048869,GO:0050776,GO:0050778,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050851,GO:0050852,GO:0050854,GO:0050856,GO:0050863,GO:0050865,GO:0050867,GO:0050870,GO:0050896,GO:0051090,GO:0051091,GO:0051092,GO:0051094,GO:0051168,GO:0051169,GO:0051171,GO:0051173,GO:0051174,GO:0051179,GO:0051234,GO:0051239,GO:0051240,GO:0051246,GO:0051247,GO:0051249,GO:0051251,GO:0051252,GO:0051259,GO:0051338,GO:0051347,GO:0051641,GO:0051649,GO:0051704,GO:0051707,GO:0051716,GO:0060255,GO:0060548,GO:0065003,GO:0065007,GO:0065009,GO:0070011,GO:0070013,GO:0070647,GO:0070661,GO:0071704,GO:0071840,GO:0080090,GO:0080134,GO:0140096,GO:1901222,GO:1901224,GO:1901564,GO:1902105,GO:1902107,GO:1902531,GO:1902533,GO:1903037,GO:1903039,GO:1903320,GO:1903322,GO:1903506,GO:1903706,GO:1903708,GO:2000026,GO:2000112,GO:2000316,GO:2000318,GO:2000319,GO:2000321,GO:2000514,GO:2000516,GO:2001141	-	ko:K07369	ko04064,ko04660,ko04662,ko05152,map04064,map04660,map04662,map05152	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Ig_2,Ig_3,Peptidase_C14
k141_1205_2	273116.14324532	1.39e-10	65.1	COG0030@1|root,arCOG04131@2157|Archaea,2XU1Q@28890|Euryarchaeota,241VH@183967|Thermoplasmata	183967|Thermoplasmata	J	Ribosomal RNA adenine dimethylases	ksgA	-	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
k141_3876_2	1111732.AZOD01000025_gene1733	1.38e-52	174.0	COG2227@1|root,COG2227@2|Bacteria,1QUAF@1224|Proteobacteria,1S2ZT@1236|Gammaproteobacteria	1236|Gammaproteobacteria	H	COG0500 SAM-dependent methyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23,Methyltransf_25
k141_3876_3	1304885.AUEY01000038_gene2578	1.07e-34	123.0	COG1832@1|root,COG1832@2|Bacteria,1PUW7@1224|Proteobacteria,42T5D@68525|delta/epsilon subdivisions,2WPHZ@28221|Deltaproteobacteria,2MK69@213118|Desulfobacterales	28221|Deltaproteobacteria	S	CoA binding domain	-	-	-	ko:K06929	-	-	-	-	ko00000	-	-	-	CoA_binding_2
k141_4198_1	1504672.669783588	1.65e-58	232.0	COG2931@1|root,COG3210@1|root,COG4625@1|root,COG2931@2|Bacteria,COG3210@2|Bacteria,COG4625@2|Bacteria,1MU7T@1224|Proteobacteria	1224|Proteobacteria	Q	COG2931, RTX toxins and related Ca2 -binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	DUF4347,DUF5122,HemolysinCabind,Lactonase,Laminin_G_3,Peptidase_M10_C,W_rich_C
k141_4198_2	1535422.ND16A_3200	5.67e-10	60.8	COG1262@1|root,COG1262@2|Bacteria,1Q227@1224|Proteobacteria,1RQEK@1236|Gammaproteobacteria,2Q7K8@267889|Colwelliaceae	1236|Gammaproteobacteria	S	SapC	-	-	-	-	-	-	-	-	-	-	-	-	SapC
k141_214_1	1121405.dsmv_2307	5.08e-206	580.0	COG1032@1|root,COG1032@2|Bacteria,1MY2Y@1224|Proteobacteria,42NG3@68525|delta/epsilon subdivisions,2WJ95@28221|Deltaproteobacteria,2MJ57@213118|Desulfobacterales	28221|Deltaproteobacteria	C	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,DUF4070,Radical_SAM
k141_214_3	96561.Dole_2319	7.22e-30	110.0	COG1359@1|root,COG1359@2|Bacteria,1NGPW@1224|Proteobacteria,42TXG@68525|delta/epsilon subdivisions,2WQI4@28221|Deltaproteobacteria,2MKN6@213118|Desulfobacterales	28221|Deltaproteobacteria	S	PFAM Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	ABM
k141_214_4	1123354.AUDR01000002_gene1533	2.46e-19	95.1	COG2885@1|root,COG2885@2|Bacteria,1MYBP@1224|Proteobacteria,2VR0Y@28216|Betaproteobacteria,1KSTY@119069|Hydrogenophilales	119069|Hydrogenophilales	M	YMGG-like Gly-zipper	-	-	-	-	-	-	-	-	-	-	-	-	Gly-zipper_YMGG,OmpA
k141_214_6	177437.HRM2_03790	5.46e-251	701.0	COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,42MEA@68525|delta/epsilon subdivisions,2WIW6@28221|Deltaproteobacteria,2MI74@213118|Desulfobacterales	28221|Deltaproteobacteria	KT	Sigma-54 interaction domain	-	-	2.1.1.80	ko:K00575	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	HTH_8,PAS_4,PAS_9,Sigma54_activat
k141_214_7	1000565.METUNv1_01153	7.31e-151	461.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,2KVRJ@206389|Rhodocyclales	206389|Rhodocyclales	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS,Response_reg
k141_214_8	525897.Dbac_2238	4.15e-236	663.0	COG0467@1|root,COG0467@2|Bacteria,1NEWW@1224|Proteobacteria,42YYA@68525|delta/epsilon subdivisions,2WTU4@28221|Deltaproteobacteria,2MBHQ@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	KaiC	-	-	-	ko:K08482	-	-	-	-	ko00000	-	-	-	ATPase
k141_214_9	525897.Dbac_2239	6.43e-19	84.0	2EJ4X@1|root,33CW5@2|Bacteria,1NITR@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_5187_1	1437882.AZRU01000022_gene6353	1.04e-10	71.2	COG2304@1|root,COG2931@1|root,COG2304@2|Bacteria,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,1S3Q4@1236|Gammaproteobacteria,1YG4I@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	Q	COG2931, RTX toxins and related Ca2 -binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin_3,Calx-beta,DUF4114,HemolysinCabind,VWA,VWA_2
k141_5187_2	1246459.KB898353_gene347	6.15e-11	75.1	COG1345@1|root,COG2931@1|root,COG2982@1|root,COG3209@1|root,COG3210@1|root,COG5295@1|root,COG1345@2|Bacteria,COG2931@2|Bacteria,COG2982@2|Bacteria,COG3209@2|Bacteria,COG3210@2|Bacteria,COG5295@2|Bacteria,1MU7T@1224|Proteobacteria,2TRVY@28211|Alphaproteobacteria,4BB16@82115|Rhizobiaceae	28211|Alphaproteobacteria	Q	COG2931 RTX toxins and related Ca2 -binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	DUF4214,DUF4347,HCBP_related,He_PIG,HemolysinCabind,Metallophos,P_proprotein,Peptidase_S8
k141_5187_3	55601.VANGNB10_cI1516c	2.05e-82	247.0	COG1451@1|root,COG1451@2|Bacteria,1RDJ9@1224|Proteobacteria,1S45M@1236|Gammaproteobacteria,1XTK3@135623|Vibrionales	135623|Vibrionales	S	Metal-dependent hydrolase	ygjP	-	-	ko:K07043	-	-	-	-	ko00000	-	-	-	DUF45
k141_5187_4	1136163.M565_ctg1P1154	2.25e-61	204.0	COG3129@1|root,COG3129@2|Bacteria,1MUI4@1224|Proteobacteria,1RMVA@1236|Gammaproteobacteria,1XTU3@135623|Vibrionales	135623|Vibrionales	J	Specifically methylates the adenine in position 1618 of 23S rRNA	rlmF	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0008988,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0052907,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.181	ko:K06970	-	-	R07232	RC00003,RC00335	ko00000,ko01000,ko03009	-	-	-	Methyltransf_10
k141_2467_1	1121459.AQXE01000007_gene702	1.49e-25	105.0	COG0119@1|root,COG0119@2|Bacteria,1MUNQ@1224|Proteobacteria,42MSP@68525|delta/epsilon subdivisions,2WJM0@28221|Deltaproteobacteria,2M9QD@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	Belongs to the alpha-IPM synthase homocitrate synthase family	nifV	-	2.3.3.13,2.3.3.14	ko:K01649,ko:K02594	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R00271,R01213	RC00004,RC00067,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like
k141_2467_2	96561.Dole_0551	3.51e-250	694.0	COG0004@1|root,COG0004@2|Bacteria,1NR9F@1224|Proteobacteria,42M8M@68525|delta/epsilon subdivisions,2WJE2@28221|Deltaproteobacteria,2MISS@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Ammonium Transporter	-	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
k141_2467_3	1121456.ATVA01000018_gene316	4.26e-44	146.0	COG0347@1|root,COG0347@2|Bacteria,1RGWK@1224|Proteobacteria,42SJJ@68525|delta/epsilon subdivisions,2WP4E@28221|Deltaproteobacteria,2MBZ0@213115|Desulfovibrionales	28221|Deltaproteobacteria	K	Belongs to the P(II) protein family	-	-	-	ko:K04751	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	P-II
k141_2167_1	55601.VANGNB10_cII0079	0.0	1089.0	COG0542@1|root,COG0542@2|Bacteria,1MVBH@1224|Proteobacteria,1RMZH@1236|Gammaproteobacteria,1XTVD@135623|Vibrionales	135623|Vibrionales	O	Belongs to the ClpA ClpB family	-	-	-	ko:K11907	ko02025,ko03070,map02025,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
k141_2167_2	55601.VANGNB10_cII0080	1.87e-219	623.0	COG3829@1|root,COG3829@2|Bacteria,1MY61@1224|Proteobacteria,1RQWE@1236|Gammaproteobacteria,1XTZZ@135623|Vibrionales	135623|Vibrionales	K	Transcriptional regulator	-	-	-	ko:K11908	-	-	-	-	ko00000,ko03000	-	-	-	HTH_8,Sigma54_activat
k141_2167_3	870967.VIS19158_07015	3.71e-55	182.0	2C9Y5@1|root,32RR9@2|Bacteria,1N3SX@1224|Proteobacteria,1SBDD@1236|Gammaproteobacteria,1XUFZ@135623|Vibrionales	135623|Vibrionales	S	Type VI secretion system VasI, EvfG, VC_A0118	-	-	-	ko:K11909	-	-	-	-	ko00000,ko02044	3.A.23.1	-	-	VasI
k141_2167_4	243277.VC_A0119	2.14e-152	449.0	COG3515@1|root,COG3515@2|Bacteria,1MWDQ@1224|Proteobacteria,1RQXI@1236|Gammaproteobacteria,1XW10@135623|Vibrionales	135623|Vibrionales	S	protein conserved in bacteria	-	-	-	ko:K11910	-	M00334	-	-	ko00000,ko00002,ko02044	3.A.23.1	-	-	ImpA_N,T6SS_VasJ
k141_2167_5	243277.VC_A0120	0.0	1675.0	COG3523@1|root,COG3523@2|Bacteria,1MV3D@1224|Proteobacteria,1RPQ2@1236|Gammaproteobacteria,1XSAX@135623|Vibrionales	135623|Vibrionales	S	protein conserved in bacteria	-	-	-	ko:K11891	ko02025,ko03070,map02025,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	IcmF-related,IcmF_C,ImcF-related_N
k141_2167_6	55601.VANGNB10_cII0974c	6.5e-247	712.0	COG3409@1|root,COG3501@1|root,COG3409@2|Bacteria,COG3501@2|Bacteria,1MU7Q@1224|Proteobacteria,1RMZS@1236|Gammaproteobacteria,1XUHW@135623|Vibrionales	135623|Vibrionales	M	protein conserved in bacteria	vgrG1	GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0006464,GO:0006807,GO:0006996,GO:0007010,GO:0007015,GO:0008144,GO:0008150,GO:0008152,GO:0008154,GO:0009405,GO:0009987,GO:0016043,GO:0016874,GO:0016879,GO:0016881,GO:0017076,GO:0018149,GO:0018153,GO:0018193,GO:0018199,GO:0018205,GO:0018262,GO:0018995,GO:0019538,GO:0022411,GO:0030029,GO:0030036,GO:0030042,GO:0030430,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032984,GO:0033643,GO:0033646,GO:0035639,GO:0036094,GO:0036211,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0043624,GO:0043656,GO:0043657,GO:0043933,GO:0044215,GO:0044216,GO:0044217,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044419,GO:0046872,GO:0051261,GO:0051704,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:0097435,GO:1901265,GO:1901363,GO:1901564	-	ko:K11904	ko03070,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	PG_binding_1,Phage_GPD
k141_4199_2	96561.Dole_2891	5.43e-131	381.0	COG0730@1|root,COG0730@2|Bacteria,1PYDH@1224|Proteobacteria,42P28@68525|delta/epsilon subdivisions,2WK6D@28221|Deltaproteobacteria,2MIP7@213118|Desulfobacterales	28221|Deltaproteobacteria	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
k141_4199_3	1179773.BN6_29360	3.02e-23	102.0	COG0500@1|root,COG2226@2|Bacteria,2IJ6U@201174|Actinobacteria,4EE8H@85010|Pseudonocardiales	201174|Actinobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
k141_4199_4	1304888.ATWF01000002_gene326	1.43e-69	231.0	COG2838@1|root,COG2838@2|Bacteria,2GF78@200930|Deferribacteres	200930|Deferribacteres	C	Monomeric isocitrate dehydrogenase	-	-	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	IDH
k141_2468_2	335543.Sfum_2499	4.4e-37	138.0	COG0582@1|root,COG0582@2|Bacteria,1N2H9@1224|Proteobacteria,42NAN@68525|delta/epsilon subdivisions,2WKXF@28221|Deltaproteobacteria,2MR9R@213462|Syntrophobacterales	28221|Deltaproteobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Arm-DNA-bind_3,Phage_int_SAM_3,Phage_integrase
k141_1207_1	314292.VAS14_12804	4.66e-42	150.0	296BV@1|root,2ZTMN@2|Bacteria,1PB6M@1224|Proteobacteria,1SV9E@1236|Gammaproteobacteria,1XVNN@135623|Vibrionales	135623|Vibrionales	S	Protein of unknown function (DUF2931)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2931
k141_1207_2	675815.VOA_001964	1.44e-24	107.0	COG3673@1|root,COG3673@2|Bacteria,1QV8K@1224|Proteobacteria,1T29Z@1236|Gammaproteobacteria,1XV7E@135623|Vibrionales	135623|Vibrionales	S	Uncharacterized alpha/beta hydrolase domain (DUF2235)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2235
k141_2817_2	595494.Tola_2135	7.24e-170	492.0	COG1263@1|root,COG1264@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,1MY1V@1224|Proteobacteria,1RMYZ@1236|Gammaproteobacteria,1Y3SR@135624|Aeromonadales	135624|Aeromonadales	G	PTS system, N-acetylglucosamine-specific	nagE	-	2.7.1.193	ko:K02803,ko:K02804	ko00520,ko02060,map00520,map02060	M00267	R05199	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.1.1.15,4.A.1.1.2,4.A.1.1.5,4.A.1.1.7	-	-	PTS_EIIB,PTS_EIIC
k141_2817_3	1306174.JODP01000008_gene2810	5.12e-10	66.2	COG0583@1|root,COG0583@2|Bacteria,2GJ4Z@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
k141_2817_4	68260.JOAY01000066_gene10	2.45e-210	604.0	COG2192@1|root,COG2192@2|Bacteria,2GJHV@201174|Actinobacteria	201174|Actinobacteria	O	Carbamoyltransferase	-	-	-	ko:K00612	-	-	-	-	ko00000,ko01000	-	-	-	Carbam_trans_C,Carbam_trans_N
k141_2817_5	1166018.FAES_3901	9.54e-24	101.0	COG0637@1|root,COG0637@2|Bacteria,4NEEH@976|Bacteroidetes,47XKH@768503|Cytophagia	976|Bacteroidetes	S	HAD-hyrolase-like	pgmB	-	-	-	-	-	-	-	-	-	-	-	HAD_2
k141_2817_6	29495.EA26_08915	9.33e-226	629.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,1RSQU@1236|Gammaproteobacteria,1XTY9@135623|Vibrionales	135623|Vibrionales	JKL	Belongs to the DEAD box helicase family	rhlE-1	-	-	-	-	-	-	-	-	-	-	-	DEAD,Helicase_C
k141_2817_7	87626.PTD2_08304	3.17e-22	98.2	COG3637@1|root,COG3637@2|Bacteria,1R3QN@1224|Proteobacteria,1RY3J@1236|Gammaproteobacteria,2Q0S7@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_2817_8	234831.PSM_A1281	8.29e-35	125.0	2DBTK@1|root,32TY3@2|Bacteria,1N17B@1224|Proteobacteria,1S95N@1236|Gammaproteobacteria,2Q2W7@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_2817_9	1122197.ATWI01000010_gene875	1.7e-103	319.0	COG0475@1|root,COG0475@2|Bacteria,1R9PF@1224|Proteobacteria,1RRM1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	Sodium/hydrogen exchanger family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
k141_2817_11	243277.VC_1554	4.5e-48	165.0	COG0584@1|root,COG0584@2|Bacteria,1MU8H@1224|Proteobacteria,1RYTR@1236|Gammaproteobacteria,1XTUR@135623|Vibrionales	135623|Vibrionales	C	glycerophosphoryl diester phosphodiesterase	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
k141_2817_13	675816.VIA_003500	1.65e-115	360.0	COG0784@1|root,COG0784@2|Bacteria	2|Bacteria	T	Response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	DUF3369,DUF4388,EAL,GAF_2,GGDEF,HD,HD_5,Hpt,PAS_3,Response_reg
k141_2817_14	1111728.ATYS01000003_gene1859	1.1e-44	156.0	COG4542@1|root,COG4542@2|Bacteria,1NSRI@1224|Proteobacteria,1RPYP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	GHMP kinase	pduX_2	-	2.7.1.177	ko:K16651	ko00860,map00860	-	R06531	RC00002,RC00428	ko00000,ko00001,ko01000	-	-	-	GHMP_kinases_N
k141_215_1	1187848.AJYQ01000123_gene3138	4.29e-66	206.0	COG2885@1|root,COG2885@2|Bacteria,1MZTV@1224|Proteobacteria,1S8RG@1236|Gammaproteobacteria,1XV6J@135623|Vibrionales	135623|Vibrionales	M	Belongs to the ompA family	pal	-	-	ko:K03640	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	OmpA
k141_215_2	870967.VIS19158_14627	2.39e-161	469.0	COG0823@1|root,COG0823@2|Bacteria,1MV09@1224|Proteobacteria,1RMCY@1236|Gammaproteobacteria,1XSZN@135623|Vibrionales	135623|Vibrionales	U	Involved in the TonB-independent uptake of proteins	tolB	GO:0003674,GO:0005215	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40,TolB_N
k141_215_3	675813.VIB_000975	9.7e-61	206.0	COG3064@1|root,COG3064@2|Bacteria,1MVQS@1224|Proteobacteria,1RP2V@1236|Gammaproteobacteria,1XSTI@135623|Vibrionales	135623|Vibrionales	M	COG3064 Membrane protein involved in colicin uptake	tolA	-	-	ko:K03646	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	TolA
k141_2170_1	945543.VIBR0546_21655	9.89e-79	246.0	COG1943@1|root,COG1943@2|Bacteria,1MVUV@1224|Proteobacteria,1RNIV@1236|Gammaproteobacteria,1XTXM@135623|Vibrionales	135623|Vibrionales	L	COG1943 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_3539_2	558884.JRGM01000136_gene1096	2.19e-33	123.0	COG0671@1|root,COG0671@2|Bacteria,1N3TP@1224|Proteobacteria,1SADV@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	PFAM phosphoesterase, PA-phosphatase related	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
k141_3539_3	1116375.VEJY3_19401	1.02e-50	164.0	COG1733@1|root,COG1733@2|Bacteria,1MZ6N@1224|Proteobacteria,1S6CZ@1236|Gammaproteobacteria,1XXNN@135623|Vibrionales	135623|Vibrionales	K	transcriptional regulators	-	-	-	-	-	-	-	-	-	-	-	-	HxlR
k141_3539_4	697282.Mettu_1419	1.74e-27	102.0	COG0724@1|root,COG0724@2|Bacteria,1N6VR@1224|Proteobacteria,1SCKA@1236|Gammaproteobacteria,1XFY6@135618|Methylococcales	135618|Methylococcales	S	RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
k141_3539_6	1190603.AJYD01000015_gene1000	1.62e-74	228.0	COG1595@1|root,COG1595@2|Bacteria,1N38X@1224|Proteobacteria,1SASQ@1236|Gammaproteobacteria,1XWZT@135623|Vibrionales	135623|Vibrionales	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
k141_3539_7	1190603.AJYD01000015_gene1001	1.42e-230	654.0	COG2304@1|root,COG2304@2|Bacteria,1MUTS@1224|Proteobacteria,1RQPC@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	von willebrand factor, type A	yfbK	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	DUF3520,VWA,vWF_A
k141_3539_8	1236541.BALL01000034_gene3531	4.39e-60	188.0	COG0346@1|root,COG0346@2|Bacteria,1RH79@1224|Proteobacteria,1TARI@1236|Gammaproteobacteria,2QD5Q@267890|Shewanellaceae	1236|Gammaproteobacteria	E	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
k141_3539_9	1238450.VIBNISOn1_270005	1.94e-49	163.0	COG1670@1|root,COG1670@2|Bacteria,1RICB@1224|Proteobacteria,1SC03@1236|Gammaproteobacteria,1Y2D6@135623|Vibrionales	135623|Vibrionales	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
k141_3539_10	377629.TERTU_2895	1.19e-141	437.0	COG2730@1|root,COG5297@1|root,COG2730@2|Bacteria,COG5297@2|Bacteria,1N21U@1224|Proteobacteria,1RRB0@1236|Gammaproteobacteria,2PMTI@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	G	Cellulase (glycosyl hydrolase family 5)	-	GO:0005575,GO:0005576	3.2.1.4,3.2.1.91	ko:K01179,ko:K19668	ko00500,ko01100,ko02020,map00500,map01100,map02020	-	R02886,R06200,R11307,R11308	RC00799	ko00000,ko00001,ko01000	-	GH5,GH6,GH9	-	CBM_10,CBM_5_12_2,Cellulase,TSP_3
k141_3539_12	375286.mma_0344	6.2e-55	178.0	COG3153@1|root,COG3153@2|Bacteria,1RA42@1224|Proteobacteria,2VSWJ@28216|Betaproteobacteria,478B0@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Acetyltransferase (GNAT) domain	-	-	-	ko:K03824	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_1,Acetyltransf_7,Acetyltransf_9
k141_3539_13	575788.VS_0031	8.66e-34	128.0	COG0745@1|root,COG0745@2|Bacteria,1N0YI@1224|Proteobacteria,1RMWT@1236|Gammaproteobacteria,1XUPZ@135623|Vibrionales	135623|Vibrionales	K	Transcriptional regulatory protein, C terminal	phoP	-	-	ko:K02483,ko:K07660	ko01503,ko02020,map01503,map02020	M00444,M00709,M00721,M00723,M00724,M00744	-	-	ko00000,ko00001,ko00002,ko01504,ko02022	-	-	-	Response_reg,Trans_reg_C
k141_2900_4	237368.SCABRO_01641	3.87e-316	878.0	COG0500@1|root,COG1181@1|root,COG1181@2|Bacteria,COG2226@2|Bacteria,2IYQF@203682|Planctomycetes	203682|Planctomycetes	M	Belongs to the D-alanine--D-alanine ligase family	-	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C
k141_2580_2	1121403.AUCV01000004_gene2040	1.09e-149	425.0	COG0778@1|root,COG1146@1|root,COG0778@2|Bacteria,COG1146@2|Bacteria,1R42D@1224|Proteobacteria,42Q57@68525|delta/epsilon subdivisions,2WNIW@28221|Deltaproteobacteria,2MIDH@213118|Desulfobacterales	28221|Deltaproteobacteria	C	4Fe-4S ferredoxin iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_4,Fer4_9,Nitroreductase
k141_2580_3	1121434.AULY01000009_gene2055	5.89e-40	137.0	COG0662@1|root,COG0662@2|Bacteria,1N74G@1224|Proteobacteria,430TN@68525|delta/epsilon subdivisions,2WVNI@28221|Deltaproteobacteria,2MCPU@213115|Desulfovibrionales	28221|Deltaproteobacteria	G	PFAM Cupin 2 conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,Cupin_2
k141_2580_4	94624.Bpet3920	3.51e-10	67.4	COG2207@1|root,COG2207@2|Bacteria,1QKC9@1224|Proteobacteria	1224|Proteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
k141_3711_1	177437.HRM2_22310	4.87e-39	149.0	COG0517@1|root,COG0617@1|root,COG0618@1|root,COG0517@2|Bacteria,COG0617@2|Bacteria,COG0618@2|Bacteria,1MU2X@1224|Proteobacteria,42MJJ@68525|delta/epsilon subdivisions,2WJBN@28221|Deltaproteobacteria,2MI4C@213118|Desulfobacterales	28221|Deltaproteobacteria	J	CBS domain	ccaA	-	2.7.7.72	ko:K00974	ko03013,map03013	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016	-	-	-	CBS,DHH,DHHA1,PolyA_pol,PolyA_pol_RNAbd
k141_4989_1	598467.BrE312_1462	7.04e-171	483.0	COG1879@1|root,COG1879@2|Bacteria,1QYDF@1224|Proteobacteria,1RTG8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	Periplasmic binding protein domain	-	-	-	ko:K10439	ko02010,ko02030,map02010,map02030	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	Peripla_BP_4
k141_4989_2	598467.BrE312_1463	1.08e-105	321.0	COG1129@1|root,COG1129@2|Bacteria,1MU22@1224|Proteobacteria,1RMCH@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	import. Responsible for energy coupling to the transport system	-	-	3.6.3.17	ko:K10441	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	ABC_tran
k141_2330_1	672.VV93_v1c23090	9.41e-34	118.0	COG0271@1|root,COG0271@2|Bacteria,1MZG5@1224|Proteobacteria,1S91G@1236|Gammaproteobacteria,1XYE9@135623|Vibrionales	135623|Vibrionales	T	Belongs to the BolA IbaG family	bolA	GO:0008150,GO:0008360,GO:0022603,GO:0022604,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008	-	ko:K05527	-	-	-	-	ko00000,ko03000	-	-	-	BolA
k141_2330_4	223926.28807347	1.35e-142	407.0	COG2869@1|root,COG2869@2|Bacteria,1MVDI@1224|Proteobacteria,1RR85@1236|Gammaproteobacteria,1XUPV@135623|Vibrionales	135623|Vibrionales	C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol	nqrC	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008150,GO:0008152,GO:0010181,GO:0015672,GO:0016491,GO:0016651,GO:0016655,GO:0030001,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0048037,GO:0050662,GO:0051179,GO:0051234,GO:0055114,GO:0097159,GO:0097367,GO:1901265,GO:1901363	1.6.5.8	ko:K00348	-	-	-	-	ko00000,ko01000	-	-	-	FMN_bind
k141_2330_5	675815.VOA_002621	1.72e-125	360.0	COG1347@1|root,COG1347@2|Bacteria,1MUZR@1224|Proteobacteria,1RNFE@1236|Gammaproteobacteria,1XSX6@135623|Vibrionales	135623|Vibrionales	C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol	nqrD	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008137,GO:0008150,GO:0008152,GO:0015672,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030001,GO:0030964,GO:0032991,GO:0044425,GO:0044464,GO:0050136,GO:0051179,GO:0051234,GO:0055114,GO:0071944,GO:0098796,GO:1902494	1.6.5.8	ko:K00349	-	-	-	-	ko00000,ko01000	-	-	-	Rnf-Nqr
k141_2330_7	55601.VANGNB10_cI2076c	1.3e-266	733.0	COG2871@1|root,COG2871@2|Bacteria,1QTUV@1224|Proteobacteria,1RPG5@1236|Gammaproteobacteria,1XTCQ@135623|Vibrionales	135623|Vibrionales	C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway	nqrF	GO:0000166,GO:0003674,GO:0003824,GO:0003954,GO:0005488,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008137,GO:0008150,GO:0008152,GO:0015672,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030001,GO:0030964,GO:0032991,GO:0036094,GO:0043167,GO:0043168,GO:0044425,GO:0048037,GO:0050136,GO:0050660,GO:0050662,GO:0051179,GO:0051234,GO:0051536,GO:0051537,GO:0051540,GO:0055114,GO:0071949,GO:0097159,GO:0098796,GO:1901265,GO:1901363,GO:1902494	1.6.5.8	ko:K00351	-	-	-	-	ko00000,ko01000	-	-	-	FAD_binding_6,Fer2,NAD_binding_1
k141_2330_8	545694.TREPR_0454	2.03e-22	98.2	COG2199@1|root,COG3706@2|Bacteria,2J5A2@203691|Spirochaetes	203691|Spirochaetes	T	Diguanylate cyclase (GGDEF) domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
k141_2581_1	1403946.Q615_SPAC00010G0001	2.01e-44	152.0	2DN97@1|root,32W7A@2|Bacteria,1VANB@1239|Firmicutes,4HYZ4@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_3996_1	1430331.EP10_15290	4.67e-30	113.0	COG1468@1|root,COG1468@2|Bacteria,1V781@1239|Firmicutes,4HFS8@91061|Bacilli,1WGFG@129337|Geobacillus	91061|Bacilli	L	Domain of unknown function DUF83	-	-	3.1.12.1	ko:K07464	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	Cas_Cas4
k141_3996_2	237368.SCABRO_00097	3.96e-179	505.0	COG1518@1|root,COG1518@2|Bacteria,2IXS8@203682|Planctomycetes	203682|Planctomycetes	L	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette	-	-	-	-	-	-	-	-	-	-	-	-	Cas_Cas1
k141_3996_3	986075.CathTA2_0447	3.48e-25	96.7	COG1343@1|root,COG1343@2|Bacteria,1VAV3@1239|Firmicutes,4HKKP@91061|Bacilli	91061|Bacilli	L	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette	cas2	-	-	ko:K09951	-	-	-	-	ko00000,ko02048	-	-	-	CRISPR_Cas2
k141_901_1	1304872.JAGC01000003_gene3142	5.23e-134	402.0	COG2204@1|root,COG2204@2|Bacteria,1MVWX@1224|Proteobacteria,42MIB@68525|delta/epsilon subdivisions,2WJQK@28221|Deltaproteobacteria,2M80M@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	two component, sigma54 specific, transcriptional regulator	-	-	-	ko:K02481	-	-	-	-	ko00000,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
k141_1297_1	96561.Dole_0149	8.58e-101	313.0	COG0323@1|root,COG0323@2|Bacteria,1MV61@1224|Proteobacteria,42MFX@68525|delta/epsilon subdivisions,2WJ91@28221|Deltaproteobacteria,2MIXG@213118|Desulfobacterales	28221|Deltaproteobacteria	L	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	mutL	GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391	-	ko:K03572	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	DNA_mis_repair,HATPase_c_3,MutL_C
k141_1297_2	909663.KI867150_gene317	6.6e-05	43.5	2EINH@1|root,33CDW@2|Bacteria,1NN5W@1224|Proteobacteria,437XZ@68525|delta/epsilon subdivisions,2X37U@28221|Deltaproteobacteria,2MSBT@213462|Syntrophobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_1297_3	933262.AXAM01000039_gene1153	8.23e-223	629.0	COG0154@1|root,COG0154@2|Bacteria,1MUVQ@1224|Proteobacteria,42MAH@68525|delta/epsilon subdivisions,2WJT7@28221|Deltaproteobacteria,2MI5B@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
k141_1297_4	646529.Desaci_1212	3.32e-22	89.7	COG0721@1|root,COG0721@2|Bacteria,1VEK3@1239|Firmicutes,24RIE@186801|Clostridia,262I8@186807|Peptococcaceae	186801|Clostridia	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatC	-	6.3.5.6,6.3.5.7	ko:K02435	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Glu-tRNAGln
k141_1297_6	879212.DespoDRAFT_02792	2.99e-62	209.0	COG0018@1|root,COG0018@2|Bacteria,1MU4J@1224|Proteobacteria,42MTY@68525|delta/epsilon subdivisions,2WKII@28221|Deltaproteobacteria,2MI2W@213118|Desulfobacterales	28221|Deltaproteobacteria	J	TIGRFAM arginyl-tRNA synthetase	argS	GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	iAF987.Gmet_1434	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
k141_4990_1	1116375.VEJY3_18296	3.97e-40	149.0	COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,1MU9U@1224|Proteobacteria,1RNKA@1236|Gammaproteobacteria	1236|Gammaproteobacteria	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses	nadE	-	6.3.1.5,6.3.5.1	ko:K01916,ko:K01950	ko00760,ko01100,map00760,map01100	M00115	R00189,R00257	RC00010,RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase,NAD_synthase
k141_4990_2	243277.VC_1077	5.62e-45	152.0	2AW20@1|root,31MWP@2|Bacteria,1QJNN@1224|Proteobacteria,1THPJ@1236|Gammaproteobacteria,1XX23@135623|Vibrionales	135623|Vibrionales	-	-	VC1077	-	-	-	-	-	-	-	-	-	-	-	-
k141_2582_1	29495.EA26_20220	2.55e-126	374.0	COG1027@1|root,COG1027@2|Bacteria,1R9JY@1224|Proteobacteria,1RP5Z@1236|Gammaproteobacteria,1XSMK@135623|Vibrionales	135623|Vibrionales	E	Aspartate ammonia-lyase	aspA	-	4.3.1.1	ko:K01744	ko00250,ko01100,map00250,map01100	-	R00490	RC00316,RC02799	ko00000,ko00001,ko01000	-	-	-	FumaraseC_C,Lyase_1
k141_3997_1	1304885.AUEY01000034_gene1871	1.33e-52	193.0	COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,42NYP@68525|delta/epsilon subdivisions,2WIPJ@28221|Deltaproteobacteria,2MIG6@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Belongs to the peptidase M16 family	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
k141_3712_1	1122918.KB907256_gene2319	5.62e-27	110.0	COG3449@1|root,COG3449@2|Bacteria,1V73Y@1239|Firmicutes,4HH9C@91061|Bacilli,26X5A@186822|Paenibacillaceae	91061|Bacilli	L	DNA gyrase inhibitor	yosT	-	-	-	-	-	-	-	-	-	-	-	GyrI-like
k141_902_1	377629.TERTU_1221	4.4e-58	193.0	COG1352@1|root,COG1352@2|Bacteria,1MU6W@1224|Proteobacteria,1RMFK@1236|Gammaproteobacteria,2PN8P@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	NT	Methyltransferase, chemotaxis proteins	cheR	GO:0006935,GO:0008150,GO:0009605,GO:0040011,GO:0042221,GO:0042330,GO:0050896	2.1.1.80	ko:K00575	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheR,CheR_N
k141_2901_1	1167006.UWK_01277	6.68e-23	108.0	COG3852@1|root,COG3852@2|Bacteria,1NTTH@1224|Proteobacteria,42MC9@68525|delta/epsilon subdivisions,2WIYS@28221|Deltaproteobacteria,2MHU3@213118|Desulfobacterales	28221|Deltaproteobacteria	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	2.7.13.3	ko:K07709	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,PAS_4,PAS_9
k141_2901_2	933262.AXAM01000039_gene1156	1.18e-96	294.0	COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,42NES@68525|delta/epsilon subdivisions,2WJ0V@28221|Deltaproteobacteria,2MHWD@213118|Desulfobacterales	28221|Deltaproteobacteria	NU	type II secretion system	pilC	-	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
k141_5257_1	1120998.AUFC01000009_gene2067	7.1e-38	151.0	COG1653@1|root,COG1653@2|Bacteria,1V2J4@1239|Firmicutes,25B5X@186801|Clostridia	186801|Clostridia	G	Extracellular solute-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_1,SBP_bac_8
k141_5257_2	1408422.JHYF01000018_gene1762	4.71e-61	201.0	COG1175@1|root,COG1175@2|Bacteria,1TQTC@1239|Firmicutes,24AQX@186801|Clostridia,36GI8@31979|Clostridiaceae	186801|Clostridia	G	ABC transporter, permease protein	-	-	-	ko:K02025	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
k141_5257_3	1280696.ATVY01000032_gene1392	2.29e-71	231.0	COG0395@1|root,COG0395@2|Bacteria,1TS82@1239|Firmicutes,2488S@186801|Clostridia,4BX6P@830|Butyrivibrio	186801|Clostridia	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
k141_5257_4	1121289.JHVL01000042_gene3089	0.000366	51.6	COG0845@1|root,COG0845@2|Bacteria,1UZZV@1239|Firmicutes,24AQV@186801|Clostridia,36W1J@31979|Clostridiaceae	186801|Clostridia	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3
k141_5257_6	289376.THEYE_A1198	3.22e-129	385.0	COG0057@1|root,COG0057@2|Bacteria,3J0D8@40117|Nitrospirae	40117|Nitrospirae	C	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	-	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
k141_2902_1	298655.KI912266_gene1227	5.11e-05	49.7	COG2242@1|root,COG2242@2|Bacteria	2|Bacteria	H	protein methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21
k141_1298_1	675815.VOA_003266	6.72e-30	118.0	COG3107@1|root,COG3107@2|Bacteria,1MUHR@1224|Proteobacteria,1RXX4@1236|Gammaproteobacteria,1XT66@135623|Vibrionales	135623|Vibrionales	M	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a)	lpoA	-	-	ko:K07121	-	-	-	-	ko00000	-	-	-	LppC
k141_1298_2	675813.VIB_001976	1.7e-38	132.0	COG0792@1|root,COG0792@2|Bacteria,1N6VN@1224|Proteobacteria,1SC8A@1236|Gammaproteobacteria,1XY6N@135623|Vibrionales	135623|Vibrionales	L	Belongs to the UPF0102 family	yraN	-	-	ko:K07460	-	-	-	-	ko00000	-	-	-	UPF0102
k141_903_1	572480.Arnit_2469	8.77e-24	97.1	COG0454@1|root,COG0456@2|Bacteria,1RHB7@1224|Proteobacteria,42V5R@68525|delta/epsilon subdivisions,2YSS7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Acetyltransferase (GNAT) family	-	-	2.3.1.178	ko:K06718	ko00260,ko01100,ko01120,map00260,map01100,map01120	M00033	R06978	RC00004,RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetyltransf_1
k141_3713_1	1517681.HW45_07570	9.4e-21	86.3	COG1846@1|root,COG1846@2|Bacteria,1RF8X@1224|Proteobacteria,1S4RW@1236|Gammaproteobacteria,1XX10@135623|Vibrionales	135623|Vibrionales	K	COG1846 Transcriptional regulators	-	-	-	-	-	-	-	-	-	-	-	-	MarR
k141_2584_1	425400.LS65_03005	1.04e-09	62.0	COG0511@1|root,COG5016@1|root,COG0511@2|Bacteria,COG5016@2|Bacteria,1QTTG@1224|Proteobacteria,43BUE@68525|delta/epsilon subdivisions,2YTPU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Conserved carboxylase domain	pycB	-	6.4.1.1	ko:K01960	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	M00173,M00620	R00344	RC00040,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_lipoyl,HMGL-like,PYC_OADA
k141_2584_2	331678.Cphamn1_1381	6.33e-13	69.3	COG3621@1|root,COG3621@2|Bacteria	2|Bacteria	AT	Patatin-like phospholipase	-	-	-	-	-	-	-	-	-	-	-	-	Patatin
k141_3998_1	637905.SVI_0526	1.28e-99	311.0	COG4988@1|root,COG4988@2|Bacteria,1QU1N@1224|Proteobacteria,1RNPI@1236|Gammaproteobacteria,2Q9I6@267890|Shewanellaceae	1236|Gammaproteobacteria	V	PFAM ABC transporter transmembrane region	cydD	GO:0000101,GO:0003333,GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006857,GO:0006865,GO:0006869,GO:0008150,GO:0009987,GO:0010876,GO:0015399,GO:0015405,GO:0015711,GO:0015804,GO:0015833,GO:0015849,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019725,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0032973,GO:0032991,GO:0033036,GO:0033228,GO:0034040,GO:0034220,GO:0034635,GO:0034775,GO:0035443,GO:0035672,GO:0042592,GO:0042623,GO:0042626,GO:0042883,GO:0042886,GO:0042939,GO:0043190,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0045454,GO:0046942,GO:0050789,GO:0050794,GO:0051179,GO:0051181,GO:0051234,GO:0055085,GO:0065007,GO:0065008,GO:0071702,GO:0071705,GO:0071944,GO:0072337,GO:0072348,GO:0098533,GO:0098655,GO:0098656,GO:0098796,GO:0098797,GO:0140115,GO:1902494,GO:1902495,GO:1903712,GO:1903825,GO:1904949,GO:1905039,GO:1990351	-	ko:K16013	ko02010,map02010	-	-	-	ko00000,ko00001,ko02000	3.A.1.129	-	iEC042_1314.EC042_0979,iECUMN_1333.ECUMN_1082,iETEC_1333.ETEC_0955	ABC_membrane,ABC_tran
k141_3998_2	357804.Ping_3453	1.21e-136	405.0	COG4987@1|root,COG4987@2|Bacteria,1QU1P@1224|Proteobacteria,1RQD7@1236|Gammaproteobacteria,2QIIE@267894|Psychromonadaceae	1236|Gammaproteobacteria	V	ABC transporter transmembrane region	cydC	GO:0000101,GO:0003333,GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006857,GO:0006865,GO:0008150,GO:0009889,GO:0015399,GO:0015405,GO:0015711,GO:0015804,GO:0015833,GO:0015849,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019222,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0031323,GO:0031326,GO:0032973,GO:0032991,GO:0033228,GO:0034220,GO:0034635,GO:0034775,GO:0035443,GO:0035672,GO:0042623,GO:0042626,GO:0042883,GO:0042886,GO:0042939,GO:0043190,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0050789,GO:0050794,GO:0051171,GO:0051179,GO:0051181,GO:0051193,GO:0051234,GO:0055085,GO:0065007,GO:0070453,GO:0071702,GO:0071705,GO:0071944,GO:0072337,GO:0072348,GO:0098533,GO:0098655,GO:0098656,GO:0098796,GO:0098797,GO:0140115,GO:1901401,GO:1901463,GO:1902494,GO:1902495,GO:1903712,GO:1903825,GO:1904949,GO:1905039,GO:1990351	-	ko:K16012	ko02010,map02010	-	-	-	ko00000,ko00001,ko02000	3.A.1.129	-	iEC55989_1330.EC55989_0931,iECIAI1_1343.ECIAI1_0926,iECO103_1326.ECO103_0929,iECO111_1330.ECO111_0954,iECSE_1348.ECSE_0944,iECW_1372.ECW_m0996,iEKO11_1354.EKO11_2951,iSDY_1059.SDY_2375,iWFL_1372.ECW_m0996	ABC_membrane,ABC_tran
k141_4992_2	1082933.MEA186_00741	5.59e-136	396.0	COG4608@1|root,COG4608@2|Bacteria,1NU4K@1224|Proteobacteria,2TT4U@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
k141_4992_3	1082933.MEA186_00746	9.59e-30	115.0	COG0444@1|root,COG0444@2|Bacteria,1R4KB@1224|Proteobacteria,2TR0J@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K02031	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
k141_2334_1	1348635.BBJY01000026_gene2276	9.01e-69	216.0	COG0500@1|root,COG2226@2|Bacteria,1RFBE@1224|Proteobacteria,1SDWD@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23
k141_2334_2	1249480.B649_08465	1.98e-195	550.0	COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,42N27@68525|delta/epsilon subdivisions,2YN0W@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Belongs to the DegT DnrJ EryC1 family	-	-	2.6.1.59	ko:K02805	-	-	-	-	ko00000,ko01000,ko01007	-	-	-	DegT_DnrJ_EryC1
k141_2008_1	266748.HY04_12875	9.17e-25	108.0	COG0827@1|root,COG1002@1|root,COG0827@2|Bacteria,COG1002@2|Bacteria,4NEHR@976|Bacteroidetes,1HYJU@117743|Flavobacteriia,3ZS67@59732|Chryseobacterium	976|Bacteroidetes	L	TaqI-like C-terminal specificity domain	-	-	-	-	-	-	-	-	-	-	-	-	Eco57I,N6_Mtase,TaqI_C
k141_2008_2	1304284.L21TH_1654	7.35e-28	103.0	COG0721@1|root,COG0721@2|Bacteria,1VEK3@1239|Firmicutes,24RIE@186801|Clostridia,36MP3@31979|Clostridiaceae	186801|Clostridia	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatC	-	6.3.5.6,6.3.5.7	ko:K02435	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Glu-tRNAGln
k141_1571_6	870967.VIS19158_02465	1.37e-34	120.0	2BMU6@1|root,32GDQ@2|Bacteria,1QKGY@1224|Proteobacteria,1TIM3@1236|Gammaproteobacteria,1XZBG@135623|Vibrionales	135623|Vibrionales	S	Ogr/Delta-like zinc finger	-	-	-	-	-	-	-	-	-	-	-	-	Ogr_Delta
k141_1571_8	870967.VIS19158_03986	0.0	1083.0	28HIF@1|root,2Z7TX@2|Bacteria,1MY24@1224|Proteobacteria,1RN69@1236|Gammaproteobacteria,1XWMY@135623|Vibrionales	135623|Vibrionales	S	Bacteriophage replication gene A protein (GPA)	-	-	-	-	-	-	-	-	-	-	-	-	Phage_GPA
k141_1571_10	870967.VIS19158_03996	1.28e-35	122.0	2B58X@1|root,31NS4@2|Bacteria,1QKGA@1224|Proteobacteria,1TIKE@1236|Gammaproteobacteria,1XZA5@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_1571_11	1187848.AJYQ01000156_gene3841	5.93e-70	213.0	2AQRN@1|root,31FZF@2|Bacteria,1QDS0@1224|Proteobacteria,1THWB@1236|Gammaproteobacteria,1XXQK@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_1571_12	675816.VIA_001533	1.08e-62	195.0	2B3FY@1|root,31W4X@2|Bacteria,1QJWF@1224|Proteobacteria,1THY7@1236|Gammaproteobacteria,1XXW4@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_1571_14	1219077.VAZ01S_049_00390	2.8e-53	174.0	2BX0J@1|root,30H36@2|Bacteria,1R6TW@1224|Proteobacteria,1RZIA@1236|Gammaproteobacteria,1XWQD@135623|Vibrionales	135623|Vibrionales	S	Phage regulatory protein CII (CP76)	-	-	-	-	-	-	-	-	-	-	-	-	Phage_CP76
k141_1571_15	945550.VISI1226_20540	2.57e-21	87.0	2E3UI@1|root,32YRW@2|Bacteria,1N9KV@1224|Proteobacteria,1SDJX@1236|Gammaproteobacteria,1XZMB@135623|Vibrionales	135623|Vibrionales	S	Pyocin activator protein PrtN	-	-	-	-	-	-	-	-	-	-	-	-	PyocinActivator
k141_1571_16	945543.VIBR0546_09077	6.22e-26	110.0	COG2932@1|root,COG2932@2|Bacteria,1RG5I@1224|Proteobacteria,1TB9W@1236|Gammaproteobacteria,1XXX5@135623|Vibrionales	135623|Vibrionales	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Tnp_Mu_1,Peptidase_S24
k141_4731_1	96561.Dole_2490	1.34e-76	245.0	COG0165@1|root,COG0165@2|Bacteria,1MUTU@1224|Proteobacteria,42M7Y@68525|delta/epsilon subdivisions,2WIRN@28221|Deltaproteobacteria,2MHTS@213118|Desulfobacterales	28221|Deltaproteobacteria	E	TIGRFAM argininosuccinate lyase	argH	GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ASL_C2,Lyase_1,NUDIX
k141_2023_1	94122.Shewana3_0168	7.11e-51	182.0	COG2931@1|root,COG3637@1|root,COG4932@1|root,COG2931@2|Bacteria,COG3637@2|Bacteria,COG4932@2|Bacteria,1MU7T@1224|Proteobacteria,1RNK8@1236|Gammaproteobacteria,2QA62@267890|Shewanellaceae	1236|Gammaproteobacteria	MQ	Dystroglycan-type cadherin domain protein	-	-	-	ko:K11005	-	-	-	-	ko00000,ko02000,ko02042	1.C.11	-	-	Cadherin_3,Calx-beta,He_PIG,HemolysinCabind,VWA_2
k141_4023_2	525898.Sdel_1574	1.29e-159	484.0	COG1629@1|root,COG4771@2|Bacteria,1MWKN@1224|Proteobacteria,42MNM@68525|delta/epsilon subdivisions,2YPZ9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	TonB-dependent receptor	-	-	-	ko:K02014,ko:K15721	-	-	-	-	ko00000,ko02000	1.B.14,1.B.14.7.2	-	-	Plug,TonB_dep_Rec
k141_4023_3	575590.HMPREF0156_00410	5.63e-66	219.0	COG1132@1|root,COG1132@2|Bacteria,4NG32@976|Bacteroidetes	976|Bacteroidetes	V	ABC transporter, ATP-binding protein	lmrA	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
k141_2024_1	1307759.JOMJ01000004_gene2768	6.03e-47	165.0	COG2200@1|root,COG2200@2|Bacteria,1MVJY@1224|Proteobacteria,42S4U@68525|delta/epsilon subdivisions,2WTJ9@28221|Deltaproteobacteria,2MA5C@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL
k141_655_1	667014.Thein_0990	4.43e-14	72.0	COG1514@1|root,COG1514@2|Bacteria,2GHRT@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	J	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester	-	-	3.1.4.58	ko:K01975	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	LigT_PEase
k141_655_2	177437.HRM2_27340	2.26e-184	520.0	COG0468@1|root,COG0468@2|Bacteria,1MU3C@1224|Proteobacteria,42M69@68525|delta/epsilon subdivisions,2WIYC@28221|Deltaproteobacteria,2MI4Q@213118|Desulfobacterales	28221|Deltaproteobacteria	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
k141_655_3	933262.AXAM01000025_gene3420	0.0	997.0	COG0013@1|root,COG0013@2|Bacteria,1MU9A@1224|Proteobacteria,42M70@68525|delta/epsilon subdivisions,2WJA8@28221|Deltaproteobacteria,2MHQW@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
k141_5010_1	1219065.VPR01S_09_00980	2.23e-55	174.0	COG1534@1|root,COG1534@2|Bacteria,1N8K5@1224|Proteobacteria,1SDIM@1236|Gammaproteobacteria,1XXTH@135623|Vibrionales	135623|Vibrionales	J	RNA-binding protein containing KH domain, possibly ribosomal protein	yhbY	-	-	ko:K07574	-	-	-	-	ko00000,ko03009	-	-	-	CRS1_YhbY
k141_5010_3	223926.28807465	1.75e-104	317.0	COG3203@1|root,COG3203@2|Bacteria,1QTID@1224|Proteobacteria,1SWVI@1236|Gammaproteobacteria,1XSFV@135623|Vibrionales	135623|Vibrionales	M	COG3203 Outer membrane protein (porin)	ompU	GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944	-	ko:K08720	ko01501,ko05111,map01501,map05111	-	-	-	ko00000,ko00001,ko02000	1.B.1.2.1	-	-	Porin_1,Porin_4
k141_5010_4	223926.28807466	1.72e-181	523.0	COG2027@1|root,COG2027@2|Bacteria,1MW40@1224|Proteobacteria,1RP8V@1236|Gammaproteobacteria,1XUAV@135623|Vibrionales	135623|Vibrionales	M	COG2027 D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 4)	dacB	-	3.4.16.4	ko:K07259	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S13
k141_5010_5	675813.VIB_000264	3.8e-256	706.0	COG0162@1|root,COG0162@2|Bacteria,1MVUQ@1224|Proteobacteria,1RPKC@1236|Gammaproteobacteria,1XVI5@135623|Vibrionales	135623|Vibrionales	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006437,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
k141_5010_6	675813.VIB_000265	1.47e-221	621.0	COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,1RM7S@1236|Gammaproteobacteria,1XUZ4@135623|Vibrionales	135623|Vibrionales	M	COG0739 Membrane proteins related to metalloendopeptidases	yebA	-	-	-	-	-	-	-	-	-	-	-	OapA,OapA_N,Peptidase_M23
k141_1573_1	1056512.D515_03615	3.68e-159	452.0	COG0598@1|root,COG0598@2|Bacteria,1MWMP@1224|Proteobacteria,1RNDQ@1236|Gammaproteobacteria,1XSHR@135623|Vibrionales	135623|Vibrionales	P	Mediates influx of magnesium ions	corA	-	-	-	-	-	-	-	-	-	-	-	CorA
k141_4024_1	644282.Deba_2486	2.11e-22	98.6	COG1629@1|root,COG4771@2|Bacteria,1MWKN@1224|Proteobacteria,42MNM@68525|delta/epsilon subdivisions,2WMEW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	COGs COG1629 Outer membrane receptor protein mostly Fe transport	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
k141_2609_1	617140.AJZE01000076_gene1242	9.17e-38	132.0	COG0110@1|root,COG0110@2|Bacteria,1MUCJ@1224|Proteobacteria,1RPPT@1236|Gammaproteobacteria,1XU90@135623|Vibrionales	135623|Vibrionales	S	COG0110 Acetyltransferase (isoleucine patch superfamily)	-	-	2.3.1.28	ko:K00638	-	-	-	-	br01600,ko00000,ko01000,ko01504	-	-	-	Hexapep
k141_412_1	1304885.AUEY01000016_gene3073	3.46e-27	112.0	COG2067@1|root,COG2067@2|Bacteria,1MUU4@1224|Proteobacteria,42N9J@68525|delta/epsilon subdivisions,2WK7H@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	PFAM membrane protein involved in aromatic hydrocarbon degradation	-	-	-	ko:K06076	-	-	-	-	ko00000,ko02000	1.B.9	-	-	Toluene_X
k141_5120_1	1476973.JMMB01000007_gene539	2.08e-57	189.0	COG0727@1|root,COG0727@2|Bacteria,1VIET@1239|Firmicutes,24UUA@186801|Clostridia,25S95@186804|Peptostreptococcaceae	186801|Clostridia	S	Putative zinc- or iron-chelating domain	-	-	-	-	-	-	-	-	-	-	-	-	CxxCxxCC
k141_5120_2	1391646.AVSU01000075_gene2795	5.73e-136	402.0	COG0477@1|root,COG2814@2|Bacteria,1TS1D@1239|Firmicutes,24CUT@186801|Clostridia,25TU4@186804|Peptostreptococcaceae	186801|Clostridia	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_1_like,Sugar_tr
k141_5120_3	1121324.CLIT_10c03990	4.05e-115	341.0	COG0697@1|root,COG0697@2|Bacteria,1TRKE@1239|Firmicutes,249RU@186801|Clostridia,25TGR@186804|Peptostreptococcaceae	186801|Clostridia	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
k141_5120_4	1121324.CLIT_2c01920	0.0	1180.0	COG0446@1|root,COG0607@1|root,COG2210@1|root,COG0446@2|Bacteria,COG0607@2|Bacteria,COG2210@2|Bacteria,1TPWW@1239|Firmicutes,2484C@186801|Clostridia,25QTC@186804|Peptostreptococcaceae	186801|Clostridia	P	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain	cdr	-	-	-	-	-	-	-	-	-	-	-	DrsE_2,Pyr_redox_2,Pyr_redox_dim,Rhodanese,TusA
k141_5120_5	1131462.DCF50_p1615	1.09e-34	121.0	COG0640@1|root,COG0640@2|Bacteria,1VF14@1239|Firmicutes,24MW7@186801|Clostridia,262SE@186807|Peptococcaceae	186801|Clostridia	K	helix_turn_helix, Arsenical Resistance Operon Repressor	pagR	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
k141_5120_6	1304284.L21TH_0336	7.33e-144	415.0	COG1242@1|root,COG1242@2|Bacteria,1TQ57@1239|Firmicutes,247U3@186801|Clostridia,36DHV@31979|Clostridiaceae	186801|Clostridia	S	radical SAM protein	-	-	-	ko:K07139	-	-	-	-	ko00000	-	-	-	Radical_SAM,Radical_SAM_C
k141_5120_7	500633.CLOHIR_01707	1.08e-19	84.3	2EBCU@1|root,335DI@2|Bacteria,1VENS@1239|Firmicutes,24T2K@186801|Clostridia,25TNR@186804|Peptostreptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_5120_8	1095747.HMPREF1049_1678	3.71e-88	275.0	COG0502@1|root,COG0502@2|Bacteria,379PA@32066|Fusobacteria	32066|Fusobacteria	H	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism	bioB	-	2.8.1.6	ko:K01012	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R01078	RC00441	ko00000,ko00001,ko00002,ko01000	-	-	-	BATS,Radical_SAM
k141_5120_9	1121289.JHVL01000012_gene1709	1.5e-153	449.0	COG3681@1|root,COG3681@2|Bacteria,1TQF5@1239|Firmicutes,2488Q@186801|Clostridia,36EM7@31979|Clostridiaceae	186801|Clostridia	S	Belongs to the UPF0597 family	-	-	-	-	-	-	-	-	-	-	-	-	SDH_alpha
k141_5120_10	1286171.EAL2_c07210	2.74e-105	318.0	arCOG05878@1|root,2ZC5B@2|Bacteria,1V210@1239|Firmicutes,24GVY@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_5120_11	1121324.CLIT_10c04010	6.13e-48	163.0	COG0622@1|root,COG0622@2|Bacteria,1VBP8@1239|Firmicutes,24PBU@186801|Clostridia	186801|Clostridia	S	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
k141_5120_12	1280692.AUJL01000017_gene1028	5.93e-57	190.0	COG1752@1|root,COG1752@2|Bacteria,1V1ST@1239|Firmicutes,24GJT@186801|Clostridia,36IU0@31979|Clostridiaceae	186801|Clostridia	S	Patatin-like phospholipase	-	-	-	-	-	-	-	-	-	-	-	-	Patatin
k141_5120_13	1128398.Curi_c17620	5.81e-179	513.0	COG1362@1|root,COG1362@2|Bacteria,1TQ3Z@1239|Firmicutes,248UP@186801|Clostridia,268K1@186813|unclassified Clostridiales	186801|Clostridia	E	Aminopeptidase I zinc metalloprotease (M18)	apeB	-	3.4.11.21	ko:K01267	-	-	-	-	ko00000,ko01000,ko01002,ko04131	-	-	-	Peptidase_M18
k141_5120_14	1286171.EAL2_c16430	5.56e-317	891.0	COG0210@1|root,COG0210@2|Bacteria,1TPSU@1239|Firmicutes,247RM@186801|Clostridia,25VCX@186806|Eubacteriaceae	186801|Clostridia	L	DNA helicase	pcrA	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
k141_5120_15	1286171.EAL2_808p06750	9.22e-207	585.0	COG0534@1|root,COG0534@2|Bacteria,1TPFM@1239|Firmicutes,247J9@186801|Clostridia,25UUM@186806|Eubacteriaceae	186801|Clostridia	V	MATE efflux family protein	-	-	-	-	-	-	-	-	-	-	-	-	MatE
k141_5120_16	1121342.AUCO01000019_gene1209	6.18e-123	365.0	COG0473@1|root,COG0473@2|Bacteria,1TPEM@1239|Firmicutes,24A63@186801|Clostridia,36E5F@31979|Clostridiaceae	186801|Clostridia	C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate	leuB	-	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
k141_5120_17	445971.ANASTE_01888	1.37e-62	197.0	COG0066@1|root,COG0066@2|Bacteria,1V1I6@1239|Firmicutes,24FUI@186801|Clostridia,25W2J@186806|Eubacteriaceae	186801|Clostridia	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuD	-	4.2.1.33,4.2.1.35,4.2.1.85	ko:K01704,ko:K20453	ko00290,ko00660,ko00760,ko01100,ko01110,ko01120,ko01210,ko01230,map00290,map00660,map00760,map01100,map01110,map01120,map01210,map01230	M00432,M00535	R03069,R03896,R03898,R03968,R04001,R10170	RC00843,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase_C
k141_5120_18	521460.Athe_2101	4.76e-204	576.0	COG0065@1|root,COG0065@2|Bacteria,1TPE5@1239|Firmicutes,2484F@186801|Clostridia,42F1K@68295|Thermoanaerobacterales	186801|Clostridia	H	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuC	-	4.2.1.33,4.2.1.35,4.2.1.85	ko:K01703,ko:K20452	ko00290,ko00660,ko00760,ko00966,ko01100,ko01110,ko01120,ko01210,ko01230,map00290,map00660,map00760,map00966,map01100,map01110,map01120,map01210,map01230	M00432,M00535	R03069,R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00843,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS04465	Aconitase
k141_5120_19	1286171.EAL2_c00790	5.53e-219	621.0	COG0119@1|root,COG0119@2|Bacteria,1TP4Y@1239|Firmicutes,2485A@186801|Clostridia,25VMR@186806|Eubacteriaceae	186801|Clostridia	E	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)	leuA	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
k141_5120_20	272623.L0248	1.33e-12	68.9	COG1846@1|root,COG1846@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	rmaA	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
k141_5120_21	192952.MM_3194	3.12e-93	296.0	COG0534@1|root,arCOG01731@2157|Archaea,2XU54@28890|Euryarchaeota,2NAD4@224756|Methanomicrobia	224756|Methanomicrobia	V	Polysaccharide biosynthesis C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MatE
k141_5120_23	1511.CLOST_0907	0.0	900.0	COG3383@1|root,COG4624@1|root,COG3383@2|Bacteria,COG4624@2|Bacteria,1TP6C@1239|Firmicutes,24897@186801|Clostridia	186801|Clostridia	C	hydrogenase large subunit	-	-	1.12.1.3,1.6.5.3	ko:K00336,ko:K18332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	iHN637.CLJU_RS07205	Fe_hyd_SSU,Fe_hyd_lg_C,Fer2_4,Fer4,Fer4_7,Fer4_9,NADH-G_4Fe-4S_3
k141_5120_24	1321778.HMPREF1982_02760	0.0	885.0	COG1894@1|root,COG1894@2|Bacteria,1TQB0@1239|Firmicutes,2483E@186801|Clostridia,268CT@186813|unclassified Clostridiales	186801|Clostridia	C	NADH-ubiquinone oxidoreductase-F iron-sulfur binding region	hymB	-	1.12.1.3,1.17.1.11,1.6.5.3	ko:K00335,ko:K18331,ko:K22339	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx,Complex1_51K,Fer4,NADH_4Fe-4S,SLBB
k141_5120_25	1321778.HMPREF1982_02761	3.54e-72	221.0	COG1905@1|root,COG1905@2|Bacteria,1V737@1239|Firmicutes,24HFB@186801|Clostridia,26890@186813|unclassified Clostridiales	186801|Clostridia	C	Thioredoxin-like [2Fe-2S] ferredoxin	nuoE	-	1.12.1.3,1.17.1.11,1.6.5.3	ko:K00334,ko:K18330,ko:K22340	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx
k141_93_1	1304885.AUEY01000025_gene2758	0.0	1063.0	COG1344@1|root,COG1344@2|Bacteria,1MV1N@1224|Proteobacteria,42MX8@68525|delta/epsilon subdivisions,2WJRC@28221|Deltaproteobacteria,2MISQ@213118|Desulfobacterales	28221|Deltaproteobacteria	N	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella	-	-	-	ko:K02406	ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flagellin_C,Flagellin_IN,Flagellin_N
k141_1760_1	439235.Dalk_2736	1.72e-108	318.0	COG5266@1|root,COG5266@2|Bacteria,1PVKN@1224|Proteobacteria,42PYV@68525|delta/epsilon subdivisions,2WK2G@28221|Deltaproteobacteria,2MJ04@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Domain of unknown function (DUF4198)	-	-	-	ko:K02009	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18	-	-	DUF4198
k141_1760_2	439235.Dalk_2737	2.86e-42	141.0	2E451@1|root,32Z13@2|Bacteria,1N0RY@1224|Proteobacteria,42UM1@68525|delta/epsilon subdivisions,2WQAD@28221|Deltaproteobacteria,2MM3Q@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_1760_3	439235.Dalk_2738	0.0	976.0	COG0370@1|root,COG0370@2|Bacteria,1MUZC@1224|Proteobacteria,42MCY@68525|delta/epsilon subdivisions,2WKP8@28221|Deltaproteobacteria,2MN3W@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Ferrous iron transport protein B C terminus	-	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoB_C,FeoB_N,Gate
k141_1760_4	439235.Dalk_2739	4.2e-12	61.2	COG1918@1|root,COG1918@2|Bacteria,1Q6S0@1224|Proteobacteria,42V7E@68525|delta/epsilon subdivisions,2WS6Q@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	PFAM FeoA family protein	-	-	-	ko:K04758	-	-	-	-	ko00000,ko02000	-	-	-	FeoA
k141_1413_1	1280001.BAOA01000021_gene864	2.55e-40	133.0	COG0828@1|root,COG0828@2|Bacteria,1MZCC@1224|Proteobacteria,1S8QZ@1236|Gammaproteobacteria,1XYBV@135623|Vibrionales	135623|Vibrionales	J	Belongs to the bacterial ribosomal protein bS21 family	rpsU	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02970	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S21
k141_1413_2	1219080.VEZ01S_38_00240	4.04e-70	214.0	COG1610@1|root,COG1610@2|Bacteria,1RGZS@1224|Proteobacteria,1S61A@1236|Gammaproteobacteria,1XWVI@135623|Vibrionales	135623|Vibrionales	S	Yqey-like protein	-	-	-	ko:K09117	-	-	-	-	ko00000	-	-	-	YqeY
k141_4794_1	1116375.VEJY3_20351	5.63e-122	354.0	COG1349@1|root,COG1349@2|Bacteria,1N4W8@1224|Proteobacteria,1SAKE@1236|Gammaproteobacteria,1XWS8@135623|Vibrionales	135623|Vibrionales	K	DeoR C terminal sensor domain	-	-	-	ko:K22103	-	-	-	-	ko00000,ko03000	-	-	-	DeoRC,HTH_DeoR
k141_3466_1	1307761.L21SP2_1012	2.15e-69	224.0	COG2235@1|root,COG2235@2|Bacteria,2J57H@203691|Spirochaetes	203691|Spirochaetes	E	Arginine	arcA	-	3.5.3.6	ko:K01478	ko00220,ko01100,ko01110,ko01130,map00220,map01100,map01110,map01130	-	R00552	RC00177	ko00000,ko00001,ko01000	-	-	-	Amidinotransf
k141_3104_1	1265505.ATUG01000001_gene4623	1.04e-147	435.0	COG0477@1|root,COG2814@2|Bacteria,1R518@1224|Proteobacteria,43B4F@68525|delta/epsilon subdivisions,2WIQ4@28221|Deltaproteobacteria,2MIEM@213118|Desulfobacterales	28221|Deltaproteobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
k141_4795_1	177439.DP0391	9.03e-82	251.0	COG1075@1|root,COG1075@2|Bacteria,1N2W0@1224|Proteobacteria,42UZK@68525|delta/epsilon subdivisions,2WQ78@28221|Deltaproteobacteria,2MKM7@213118|Desulfobacterales	28221|Deltaproteobacteria	S	acetyltransferases and hydrolases with the alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_733_1	1089550.ATTH01000001_gene2115	8.87e-84	284.0	COG0577@1|root,COG0577@2|Bacteria,4PF00@976|Bacteroidetes,1FJXD@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
k141_733_2	349124.Hhal_1415	5.2e-92	288.0	COG5621@1|root,COG5621@2|Bacteria,1MUVF@1224|Proteobacteria,1RZ65@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	secreted hydrolase	attH	-	-	-	-	-	-	-	-	-	-	-	CrtC,Lipocalin_9
k141_5121_1	90814.KL370891_gene560	3.15e-06	50.4	COG0030@1|root,COG0030@2|Bacteria,1MVNU@1224|Proteobacteria,1RMHW@1236|Gammaproteobacteria,460FK@72273|Thiotrichales	72273|Thiotrichales	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	-	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
k141_5121_3	439235.Dalk_4305	5.5e-23	92.0	2D4ET@1|root,32TGZ@2|Bacteria,1RKAR@1224|Proteobacteria,42SQJ@68525|delta/epsilon subdivisions,2WP2T@28221|Deltaproteobacteria,2MK8K@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_4118_2	1286171.EAL2_c04110	1.05e-41	145.0	COG0212@1|root,COG0212@2|Bacteria,1VA91@1239|Firmicutes,24N7H@186801|Clostridia,25WW2@186806|Eubacteriaceae	186801|Clostridia	H	5-formyltetrahydrofolate cyclo-ligase	yqgN	-	6.3.3.2	ko:K01934	ko00670,ko01100,map00670,map01100	-	R02301	RC00183	ko00000,ko00001,ko01000	-	-	-	5-FTHF_cyc-lig
k141_4118_3	1121324.CLIT_13c01610	5.05e-108	317.0	COG2884@1|root,COG2884@2|Bacteria,1TP58@1239|Firmicutes,248HW@186801|Clostridia	186801|Clostridia	D	cell division ATP-binding protein FtsE	ftsE	-	-	ko:K09812	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	ABC_tran
k141_4118_4	1286171.EAL2_c04130	1.87e-105	316.0	COG2177@1|root,COG2177@2|Bacteria,1TPND@1239|Firmicutes,24AA6@186801|Clostridia,25VJS@186806|Eubacteriaceae	186801|Clostridia	D	Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation	ftsX	-	-	ko:K09811	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	FtsX
k141_4118_5	588581.Cpap_0118	1.69e-34	135.0	COG4942@1|root,COG4942@2|Bacteria,1VJ3D@1239|Firmicutes,25ERZ@186801|Clostridia,3WSIV@541000|Ruminococcaceae	186801|Clostridia	D	Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
k141_4118_6	1121324.CLIT_13c01640	2.45e-151	439.0	COG0793@1|root,COG0793@2|Bacteria,1TPBI@1239|Firmicutes,248HZ@186801|Clostridia,25QD4@186804|Peptostreptococcaceae	186801|Clostridia	M	Belongs to the peptidase S41A family	ctpA	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_S41
k141_4118_7	1499689.CCNN01000007_gene1137	8.35e-267	746.0	COG1164@1|root,COG1164@2|Bacteria,1TPV4@1239|Firmicutes,2495D@186801|Clostridia,36ET0@31979|Clostridiaceae	186801|Clostridia	E	oligoendopeptidase, M3 family	pz-A	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M3
k141_4118_8	273068.TTE1096	9.58e-91	278.0	COG0348@1|root,COG0348@2|Bacteria,1TPHF@1239|Firmicutes,247KH@186801|Clostridia,42FWZ@68295|Thermoanaerobacterales	186801|Clostridia	C	4Fe-4S binding domain	-	-	-	ko:K02574	-	-	-	-	ko00000	-	-	-	Fer4,Fer4_4,Fer4_5
k141_4118_10	555079.Toce_0777	5.81e-72	228.0	COG2116@1|root,COG2116@2|Bacteria,1TRTT@1239|Firmicutes,24BU5@186801|Clostridia,42G5C@68295|Thermoanaerobacterales	186801|Clostridia	P	Formate nitrite family of	fdhC	-	-	ko:K21993	-	-	-	-	ko00000,ko02000	1.A.16.2	-	-	Form_Nir_trans
k141_4118_11	865861.AZSU01000001_gene216	1.49e-112	335.0	COG0812@1|root,COG0812@2|Bacteria,1TP3W@1239|Firmicutes,247IU@186801|Clostridia,36DWB@31979|Clostridiaceae	186801|Clostridia	M	Cell wall formation	murB	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	-	FAD_binding_4,MurB_C
k141_4118_12	1408823.AXUS01000026_gene1552	2.83e-98	293.0	COG1387@1|root,COG1387@2|Bacteria,1TQ33@1239|Firmicutes,24CMU@186801|Clostridia,25QY2@186804|Peptostreptococcaceae	186801|Clostridia	E	DNA polymerase alpha chain like domain	-	-	-	ko:K04477	-	-	-	-	ko00000	-	-	-	PHP
k141_4118_13	596329.HMPREF0631_0474	1.02e-118	349.0	COG1660@1|root,COG1660@2|Bacteria,1TPS4@1239|Firmicutes,248KQ@186801|Clostridia,25QN8@186804|Peptostreptococcaceae	186801|Clostridia	S	Displays ATPase and GTPase activities	yvcJ	-	-	ko:K06958	-	-	-	-	ko00000,ko03019	-	-	-	ATP_bind_2
k141_4118_14	1286171.EAL2_c04510	2.77e-117	348.0	COG0391@1|root,COG0391@2|Bacteria,1TPNV@1239|Firmicutes,248G0@186801|Clostridia,25VIG@186806|Eubacteriaceae	186801|Clostridia	S	Required for morphogenesis under gluconeogenic growth conditions	-	-	-	-	-	-	-	-	-	-	-	-	UPF0052
k141_4118_15	1511.CLOST_1655	4.21e-67	206.0	COG1051@1|root,COG1051@2|Bacteria,1V4E6@1239|Firmicutes,24HPT@186801|Clostridia,25REQ@186804|Peptostreptococcaceae	186801|Clostridia	F	Belongs to the Nudix hydrolase family	apfA	-	-	-	-	-	-	-	-	-	-	-	NUDIX
k141_4118_16	1121324.CLIT_13c02020	2.93e-134	391.0	COG1481@1|root,COG1481@2|Bacteria,1TP2X@1239|Firmicutes,2484M@186801|Clostridia,25QUI@186804|Peptostreptococcaceae	186801|Clostridia	K	May be required for sporulation	whiA	-	-	ko:K09762	-	-	-	-	ko00000	-	-	-	HTH_WhiA,LAGLIDADG_WhiA,WhiA_N
k141_4118_17	754477.Q7C_1700	1.56e-19	82.4	COG1925@1|root,COG1925@2|Bacteria,1N6RM@1224|Proteobacteria,1SCXX@1236|Gammaproteobacteria,461HK@72273|Thiotrichales	72273|Thiotrichales	G	TIGRFAM Phosphotransferase System HPr (HPr) Family	-	-	-	ko:K11189	-	-	-	-	ko00000,ko02000	4.A.2.1	-	-	PTS-HPr
k141_4118_18	338963.Pcar_2035	4.02e-96	298.0	COG0438@1|root,COG0438@2|Bacteria,1NA28@1224|Proteobacteria,42NZA@68525|delta/epsilon subdivisions,2WK1T@28221|Deltaproteobacteria,43U4C@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Domain of unknown function (DUF3524)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3524,Glycos_transf_1
k141_4118_19	1476973.JMMB01000007_gene3162	0.0	1523.0	COG0587@1|root,COG0587@2|Bacteria,1TPYG@1239|Firmicutes,247U0@186801|Clostridia,25QW9@186804|Peptostreptococcaceae	186801|Clostridia	L	DNA polymerase	dnaE	-	2.7.7.7	ko:K02337,ko:K14162	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
k141_4118_20	293826.Amet_4069	1.62e-158	452.0	COG0205@1|root,COG0205@2|Bacteria,1TPF4@1239|Firmicutes,248PB@186801|Clostridia,36DGA@31979|Clostridiaceae	186801|Clostridia	F	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	pfkA	-	2.7.1.11	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	M00001,M00345	R00756,R03236,R03237,R03238,R03239,R04779	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	-	-	-	PFK
k141_4118_21	500633.CLOHIR_00682	3.96e-262	736.0	COG0469@1|root,COG0469@2|Bacteria,1TPGG@1239|Firmicutes,2489V@186801|Clostridia,25QHI@186804|Peptostreptococcaceae	186801|Clostridia	G	Pyruvate kinase	pyk	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PEP-utilizers,PK,PK_C
k141_4118_22	1121324.CLIT_13c02090	0.0	879.0	COG0733@1|root,COG0733@2|Bacteria,1TP6B@1239|Firmicutes,2485D@186801|Clostridia,25R6V@186804|Peptostreptococcaceae	186801|Clostridia	U	Sodium:neurotransmitter symporter family	-	-	-	-	-	-	-	-	-	-	-	-	SNF
k141_4118_24	1121324.CLIT_13c02110	6.82e-61	197.0	29NU7@1|root,309SB@2|Bacteria,1V68J@1239|Firmicutes,24HMM@186801|Clostridia,25RMF@186804|Peptostreptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_4118_25	1540257.JQMW01000009_gene2805	0.000863	47.0	COG1309@1|root,COG1309@2|Bacteria,1TSFG@1239|Firmicutes,24AME@186801|Clostridia,36HDI@31979|Clostridiaceae	186801|Clostridia	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
k141_4118_26	1121324.CLIT_10c05120	6.43e-74	241.0	COG0845@1|root,COG0845@2|Bacteria,1V682@1239|Firmicutes,25887@186801|Clostridia,25U8H@186804|Peptostreptococcaceae	186801|Clostridia	M	Barrel-sandwich domain of CusB or HlyD membrane-fusion	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
k141_4118_27	1121324.CLIT_10c05110	0.0	1046.0	COG0841@1|root,COG0841@2|Bacteria,1TQ03@1239|Firmicutes,2491S@186801|Clostridia,25QT4@186804|Peptostreptococcaceae	186801|Clostridia	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	nolG2	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k141_4118_28	290402.Cbei_2083	1.17e-149	443.0	COG1167@1|root,COG1167@2|Bacteria,1TPS5@1239|Firmicutes,248ZB@186801|Clostridia,36G1G@31979|Clostridiaceae	186801|Clostridia	K	helix_turn_helix gluconate operon transcriptional repressor	-	-	-	ko:K18907	-	M00700,M00702	-	-	ko00000,ko00002,ko01504,ko03000	-	-	-	Aminotran_1_2,GntR
k141_4118_29	1120985.AUMI01000011_gene144	4.42e-75	243.0	COG1171@1|root,COG1171@2|Bacteria,1TP22@1239|Firmicutes,4H1WE@909932|Negativicutes	909932|Negativicutes	E	threonine	ilvA	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,PALP
k141_4118_30	1121943.KB899990_gene3816	3.44e-42	155.0	COG2423@1|root,COG2423@2|Bacteria,1N3EI@1224|Proteobacteria,1RR4Y@1236|Gammaproteobacteria,1XPPU@135619|Oceanospirillales	135619|Oceanospirillales	E	Ornithine cyclodeaminase/mu-crystallin family	-	-	4.3.1.12	ko:K01750	ko00330,ko01110,ko01130,ko01230,map00330,map01110,map01130,map01230	-	R00671	RC00354	ko00000,ko00001,ko01000	-	-	-	OCD_Mu_crystall
k141_4118_31	1235793.C809_03163	2.16e-30	117.0	COG0572@1|root,COG0572@2|Bacteria,1V1DZ@1239|Firmicutes,24FY8@186801|Clostridia,27P4E@186928|unclassified Lachnospiraceae	186801|Clostridia	F	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	PRK
k141_4118_32	1415774.U728_171	1.81e-87	277.0	2DH55@1|root,2ZYEV@2|Bacteria,1V5RJ@1239|Firmicutes,24K2G@186801|Clostridia,36K0U@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_4118_33	293826.Amet_3695	2.04e-35	128.0	COG0716@1|root,COG0716@2|Bacteria,1VBEZ@1239|Firmicutes,24JJ6@186801|Clostridia,36K16@31979|Clostridiaceae	186801|Clostridia	C	Flavodoxin	-	-	-	-	-	-	-	-	-	-	-	-	Flavodoxin_4,Flavodoxin_5
k141_4118_34	315730.BcerKBAB4_3016	3.29e-26	111.0	COG0789@1|root,COG0789@2|Bacteria	2|Bacteria	K	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1,TipAS
k141_4118_35	869213.JCM21142_41716	5.77e-11	72.8	COG0534@1|root,COG0534@2|Bacteria,4NDUF@976|Bacteroidetes,47PPJ@768503|Cytophagia	976|Bacteroidetes	V	MatE	-	-	-	-	-	-	-	-	-	-	-	-	MatE
k141_4118_37	324057.Pjdr2_0827	4.58e-75	239.0	COG4586@1|root,COG4586@2|Bacteria,1TP1N@1239|Firmicutes,4H9NR@91061|Bacilli,26R39@186822|Paenibacillaceae	91061|Bacilli	S	ABC transporter, ATP-binding protein	drrA1	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
k141_4118_38	1449050.JNLE01000003_gene82	3.35e-13	75.5	COG4587@1|root,COG4587@2|Bacteria,1VDUN@1239|Firmicutes	1239|Firmicutes	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_6
k141_4118_39	1405.DJ92_774	1.24e-50	172.0	COG3694@1|root,COG3694@2|Bacteria,1V0CD@1239|Firmicutes,4IRS3@91061|Bacilli	91061|Bacilli	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_6
k141_4118_40	720554.Clocl_2972	5.35e-76	228.0	COG0394@1|root,COG0394@2|Bacteria,1V3JW@1239|Firmicutes,24HBX@186801|Clostridia,3WJAK@541000|Ruminococcaceae	186801|Clostridia	T	low molecular weight	arsC	-	1.20.4.1	ko:K03741	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
k141_4118_41	1122919.KB905561_gene1509	4.23e-23	109.0	COG1418@1|root,COG1418@2|Bacteria,1V7IZ@1239|Firmicutes,4HIVB@91061|Bacilli,26VIQ@186822|Paenibacillaceae	91061|Bacilli	F	phosphohydrolase	-	-	-	ko:K06950	-	-	-	-	ko00000	-	-	-	HD
k141_4118_42	439292.Bsel_0686	7.49e-32	118.0	COG4446@1|root,COG4446@2|Bacteria,1VDZG@1239|Firmicutes,4HN9R@91061|Bacilli,26Q5T@186821|Sporolactobacillaceae	91061|Bacilli	S	Protein of unknown function (DUF1499)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1499
k141_4118_43	445973.CLOBAR_00289	2.4e-199	567.0	COG2265@1|root,COG2265@2|Bacteria,1TP4H@1239|Firmicutes,248B4@186801|Clostridia,25QYW@186804|Peptostreptococcaceae	186801|Clostridia	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	rumA	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TRAM,tRNA_U5-meth_tr
k141_4464_1	1530186.JQEY01000006_gene3317	4.4e-35	134.0	COG0476@1|root,COG0476@2|Bacteria,1MW7H@1224|Proteobacteria,2TRWY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	H	Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family	moeB	-	2.7.7.80	ko:K21029	ko04122,map04122	-	R07459	RC00043	ko00000,ko00001,ko01000	-	-	-	ThiF
k141_4464_2	1235793.C809_04400	4.27e-32	117.0	COG1917@1|root,COG1917@2|Bacteria,1V2S8@1239|Firmicutes,24GIA@186801|Clostridia,27MU6@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
k141_4464_3	926561.KB900618_gene346	1.74e-37	133.0	COG0701@1|root,COG0701@2|Bacteria,1V51D@1239|Firmicutes,25DXC@186801|Clostridia	186801|Clostridia	S	Predicted permease	-	-	-	-	-	-	-	-	-	-	-	-	ArsP_1
k141_1424_14	865861.AZSU01000003_gene1953	6.45e-192	548.0	COG1263@1|root,COG1263@2|Bacteria,1TPJ8@1239|Firmicutes,24809@186801|Clostridia,36DWW@31979|Clostridiaceae	186801|Clostridia	G	Pts system	nagE	-	2.7.1.193	ko:K02803,ko:K02804	ko00520,ko02060,map00520,map02060	M00267	R05199	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.1.1.15,4.A.1.1.2,4.A.1.1.5,4.A.1.1.7	-	-	PTS_EIIB,PTS_EIIC
k141_1424_15	926561.KB900618_gene379	7.01e-55	186.0	COG3711@1|root,COG3711@2|Bacteria,1TQJJ@1239|Firmicutes,249XA@186801|Clostridia,3WB1N@53433|Halanaerobiales	186801|Clostridia	K	PFAM CAT RNA binding domain	-	-	-	ko:K03480	-	-	-	-	ko00000,ko03000	-	-	-	CAT_RBD,PRD
k141_1424_16	1169144.KB910946_gene3652	5.25e-05	53.1	COG3290@1|root,COG3829@1|root,COG3290@2|Bacteria,COG3829@2|Bacteria,1TP0E@1239|Firmicutes,4HADT@91061|Bacilli,1ZAZA@1386|Bacillus	91061|Bacilli	KT	Transcriptional regulator	bkdR	-	-	-	-	-	-	-	-	-	-	-	DapB_N,HTH_8,PAS,Sigma54_activat
k141_1424_17	1454004.AW11_00120	1.7e-31	137.0	COG2199@1|root,COG2199@2|Bacteria,1RGCV@1224|Proteobacteria,2WGRD@28216|Betaproteobacteria	28216|Betaproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF,PAS_8,Protoglobin
k141_1424_18	332101.JIBU02000043_gene1520	1.96e-160	461.0	COG0524@1|root,COG1846@1|root,COG0524@2|Bacteria,COG1846@2|Bacteria,1TQR4@1239|Firmicutes,24AUP@186801|Clostridia,36F1Z@31979|Clostridiaceae	186801|Clostridia	G	hmm pf00294	rbsK	-	2.7.1.15,2.7.1.83	ko:K00852,ko:K16328	ko00030,ko00240,map00030,map00240	-	R01051,R02750,R03315	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	HTH_24,PfkB
k141_1424_19	1211817.CCAT010000043_gene3494	3e-173	488.0	COG2313@1|root,COG2313@2|Bacteria,1TR5J@1239|Firmicutes,247J8@186801|Clostridia,36F77@31979|Clostridiaceae	186801|Clostridia	Q	Catalyzes the reversible cleavage of pseudouridine 5'- phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway	psuG	-	4.2.1.70	ko:K16329	ko00240,map00240	-	R01055	RC00432,RC00433	ko00000,ko00001,ko01000	-	-	-	Indigoidine_A
k141_1424_20	1528106.JRJE01000002_gene1985	1.16e-68	238.0	COG2199@1|root,COG2202@1|root,COG2202@2|Bacteria,COG3706@2|Bacteria,1QVHK@1224|Proteobacteria	1224|Proteobacteria	T	PAS fold	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS_3,PAS_9
k141_1424_21	1128398.Curi_c24320	1.43e-86	259.0	COG0288@1|root,COG0288@2|Bacteria,1V1EC@1239|Firmicutes,2495A@186801|Clostridia,26B2F@186813|unclassified Clostridiales	186801|Clostridia	P	Reversible hydration of carbon dioxide	cah	-	4.2.1.1	ko:K01673	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Pro_CA
k141_4590_1	177437.HRM2_06710	2.18e-43	157.0	COG1530@1|root,COG1530@2|Bacteria,1MV65@1224|Proteobacteria,42M5E@68525|delta/epsilon subdivisions,2WIV6@28221|Deltaproteobacteria,2MISJ@213118|Desulfobacterales	28221|Deltaproteobacteria	J	ribonuclease Rne Rng family	cafA	-	3.1.26.12	ko:K08300,ko:K08301	ko03018,map03018	M00394	-	-	ko00000,ko00001,ko00002,ko01000,ko03009,ko03019	-	-	-	RNase_E_G,S1
k141_244_1	999141.GME_18660	3.08e-58	182.0	COG2824@1|root,COG2824@2|Bacteria,1RGUU@1224|Proteobacteria,1S60W@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	Alkylphosphonate utilization operon protein PhnA	phnA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K06193	ko01120,map01120	-	-	-	ko00000	-	-	-	PhnA,PhnA_Zn_Ribbon
k141_244_2	1345695.CLSA_c08440	9.57e-06	52.0	COG4714@1|root,COG4714@2|Bacteria,1V3G2@1239|Firmicutes,24D6X@186801|Clostridia,36FSK@31979|Clostridiaceae	186801|Clostridia	S	Protein of unknown function (DUF2167)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2167
k141_3224_1	797302.Halru_0858	1.01e-10	66.6	COG0463@1|root,arCOG00894@2157|Archaea,2XTEG@28890|Euryarchaeota,23SDH@183963|Halobacteria	183963|Halobacteria	M	COG0463 Glycosyltransferases involved in cell wall biogenesis	gtl	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
k141_2196_2	316067.Geob_3487	1.92e-129	375.0	COG0152@1|root,COG0152@2|Bacteria,1MUR9@1224|Proteobacteria,42M8A@68525|delta/epsilon subdivisions,2WJY0@28221|Deltaproteobacteria,43UB6@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	PFAM SAICAR synthetase	purC	GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.2.6	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04591	RC00064,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	SAICAR_synt
k141_245_1	273121.WS0568	4.69e-61	199.0	COG4174@1|root,COG4174@2|Bacteria,1MVKE@1224|Proteobacteria,43BKS@68525|delta/epsilon subdivisions,2YRB3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K13894	ko02010,map02010	M00349	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.21,3.A.1.5.24	-	-	BPD_transp_1
k141_5191_1	56780.SYN_03249	1.99e-141	416.0	COG3464@1|root,COG3464@2|Bacteria,1N2V1@1224|Proteobacteria,42TEG@68525|delta/epsilon subdivisions,2WPXW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	Helix-turn-helix domain of transposase family ISL3	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3
k141_4208_1	1121405.dsmv_1338	1.21e-123	370.0	COG1538@1|root,COG1538@2|Bacteria,1MUA8@1224|Proteobacteria,42NKZ@68525|delta/epsilon subdivisions,2WIRB@28221|Deltaproteobacteria,2MHP0@213118|Desulfobacterales	28221|Deltaproteobacteria	MU	outer membrane efflux protein	-	-	-	ko:K18139	ko01501,ko02024,map01501,map02024	M00642,M00643,M00647,M00718,M00768,M00822	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	1.B.17,2.A.6.2	-	-	OEP
k141_4208_2	1121405.dsmv_1339	1.27e-238	690.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2WJVV@28221|Deltaproteobacteria,2MI7E@213118|Desulfobacterales	28221|Deltaproteobacteria	V	Hydrophobe Amphiphile Efflux-1 (HAE1) Family	acrB	-	-	ko:K03296,ko:K18138	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
k141_246_1	96561.Dole_0963	1.55e-43	151.0	COG0181@1|root,COG0181@2|Bacteria,1MU56@1224|Proteobacteria,42M84@68525|delta/epsilon subdivisions,2WJ5V@28221|Deltaproteobacteria,2MMMZ@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps	hemC	GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.61	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084	RC02317	ko00000,ko00001,ko00002,ko01000	-	-	-	Porphobil_deam,Porphobil_deamC
k141_1894_1	1121035.AUCH01000018_gene2738	4.79e-35	148.0	COG2304@1|root,COG2931@1|root,COG4932@1|root,COG2304@2|Bacteria,COG2931@2|Bacteria,COG4932@2|Bacteria,1MU7T@1224|Proteobacteria,2VKA9@28216|Betaproteobacteria,2KZXA@206389|Rhodocyclales	206389|Rhodocyclales	Q	von Willebrand factor type A domain	-	-	-	-	-	-	-	-	-	-	-	-	VWA_2
k141_5192_1	324925.Ppha_0853	8.81e-23	100.0	COG0679@1|root,COG0679@2|Bacteria	2|Bacteria	S	auxin-activated signaling pathway	-	-	-	ko:K07088	-	-	-	-	ko00000	-	-	-	Mem_trans
k141_5192_2	1304885.AUEY01000064_gene2131	2e-21	89.7	2952J@1|root,2ZSFC@2|Bacteria,1P748@1224|Proteobacteria,4323E@68525|delta/epsilon subdivisions,2WX8I@28221|Deltaproteobacteria,2MP67@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_4209_1	1121406.JAEX01000005_gene2932	9.6e-17	75.5	COG0316@1|root,COG0316@2|Bacteria,1N8FK@1224|Proteobacteria,42VBF@68525|delta/epsilon subdivisions,2WR7Y@28221|Deltaproteobacteria,2MCQR@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Belongs to the HesB IscA family	-	-	-	-	-	-	-	-	-	-	-	-	Fe-S_biosyn
k141_4209_2	1304885.AUEY01000009_gene1930	7.97e-55	175.0	28NQ4@1|root,2ZBPU@2|Bacteria,1RCN1@1224|Proteobacteria,42QPC@68525|delta/epsilon subdivisions,2WMVS@28221|Deltaproteobacteria,2MJR9@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_247_1	227377.CBU_0383	1.45e-83	252.0	COG2818@1|root,COG2818@2|Bacteria,1R9X5@1224|Proteobacteria,1S25K@1236|Gammaproteobacteria,1JCQG@118969|Legionellales	118969|Legionellales	L	Methyladenine glycosylase	tag	-	3.2.2.20	ko:K01246	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Adenine_glyco
k141_4593_1	1122165.AUHS01000002_gene3004	9.97e-18	87.4	COG0665@1|root,COG4121@1|root,COG0665@2|Bacteria,COG4121@2|Bacteria,1MZW5@1224|Proteobacteria,1RMTE@1236|Gammaproteobacteria,1JCFX@118969|Legionellales	118969|Legionellales	J	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34	mnmC	-	2.1.1.61	ko:K15461	-	-	R00601,R08702	RC00003,RC00053,RC00060,RC01483	ko00000,ko01000,ko03016	-	-	-	DAO,Methyltransf_30
k141_4593_2	1121396.KB893068_gene1450	2.85e-34	129.0	COG2848@1|root,COG2848@2|Bacteria,1NAFG@1224|Proteobacteria,42NH7@68525|delta/epsilon subdivisions,2WJJM@28221|Deltaproteobacteria,2MI2J@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Uncharacterised ACR (DUF711)	-	-	-	ko:K09157	-	-	-	-	ko00000	-	-	-	DUF711
k141_4593_3	1304885.AUEY01000023_gene2663	1.36e-136	400.0	COG2848@1|root,COG2848@2|Bacteria,1NAFG@1224|Proteobacteria,42NH7@68525|delta/epsilon subdivisions,2WJJM@28221|Deltaproteobacteria,2MI2J@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Uncharacterised ACR (DUF711)	-	-	-	ko:K09157	-	-	-	-	ko00000	-	-	-	DUF711
k141_1495_1	1190606.AJYG01000075_gene3584	1.98e-34	125.0	2AX5I@1|root,31P40@2|Bacteria,1QKT7@1224|Proteobacteria,1TIY8@1236|Gammaproteobacteria,1Y007@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_1495_2	1188252.AJYK01000028_gene580	7.3e-145	416.0	COG3547@1|root,COG3547@2|Bacteria,1MXKJ@1224|Proteobacteria,1RSCP@1236|Gammaproteobacteria,1XUHK@135623|Vibrionales	135623|Vibrionales	L	Transposase IS116/IS110/IS902 family	-	-	-	ko:K07486	-	-	-	-	ko00000	-	-	-	DEDD_Tnp_IS110,Transposase_20
k141_1495_3	1046714.AMRX01000008_gene1060	8.77e-62	191.0	COG3436@1|root,COG3436@2|Bacteria,1MZFT@1224|Proteobacteria,1SABV@1236|Gammaproteobacteria,46851@72275|Alteromonadaceae	1236|Gammaproteobacteria	L	COG3436 Transposase and inactivated derivatives	-	-	-	ko:K07484	-	-	-	-	ko00000	-	-	-	TnpB_IS66
k141_1495_4	1504981.KO116_4751	1.66e-167	492.0	COG3316@1|root,COG3316@2|Bacteria,1RHKZ@1224|Proteobacteria,1S7XK@1236|Gammaproteobacteria,1XS1N@135619|Oceanospirillales	1236|Gammaproteobacteria	L	IS66 C-terminal element	-	-	-	ko:K07484	-	-	-	-	ko00000	-	-	-	DDE_Tnp_IS66,DDE_Tnp_IS66_C,LZ_Tnp_IS66,zf-IS66
k141_1495_5	1188252.AJYK01000088_gene683	4.72e-21	90.9	COG3547@1|root,COG3547@2|Bacteria,1MXKJ@1224|Proteobacteria,1RSCP@1236|Gammaproteobacteria,1XUHK@135623|Vibrionales	135623|Vibrionales	L	Transposase IS116/IS110/IS902 family	-	-	-	ko:K07486	-	-	-	-	ko00000	-	-	-	DEDD_Tnp_IS110,Transposase_20
k141_4594_1	1408428.JNJP01000005_gene38	7.41e-24	94.4	2FFZ1@1|root,347VV@2|Bacteria,1P35I@1224|Proteobacteria,431Z9@68525|delta/epsilon subdivisions,2WWS4@28221|Deltaproteobacteria,2MCZ1@213115|Desulfovibrionales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_1231_1	517418.Ctha_0688	1.96e-74	263.0	COG0784@1|root,COG2202@1|root,COG2203@1|root,COG3829@1|root,COG4191@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG2203@2|Bacteria,COG3829@2|Bacteria,COG4191@2|Bacteria,1FEIU@1090|Chlorobi	1090|Chlorobi	T	ATP-binding region, ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_9,Response_reg
k141_1231_2	1121456.ATVA01000015_gene2219	4.29e-68	223.0	COG3366@1|root,COG3366@2|Bacteria,1P2FE@1224|Proteobacteria,42MJM@68525|delta/epsilon subdivisions,2WKGN@28221|Deltaproteobacteria,2M9JI@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	PFAM nucleoside recognition domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Gate
k141_1231_3	177437.HRM2_02720	4.89e-25	95.9	COG2331@1|root,COG2331@2|Bacteria,1NA92@1224|Proteobacteria,42VCN@68525|delta/epsilon subdivisions,2WRQP@28221|Deltaproteobacteria,2MKWP@213118|Desulfobacterales	28221|Deltaproteobacteria	S	regulatory protein, FmdB family	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
k141_1231_4	177437.HRM2_02730	2.32e-128	394.0	COG0497@1|root,COG0497@2|Bacteria,1MUNP@1224|Proteobacteria,42N50@68525|delta/epsilon subdivisions,2WJ23@28221|Deltaproteobacteria,2MHTD@213118|Desulfobacterales	28221|Deltaproteobacteria	L	May be involved in recombinational repair of damaged DNA	recN	-	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,SMC_N
k141_1231_5	1304885.AUEY01000016_gene3032	5.21e-52	168.0	COG1633@1|root,COG1633@2|Bacteria,1RGYD@1224|Proteobacteria,42T5E@68525|delta/epsilon subdivisions,2WPKD@28221|Deltaproteobacteria,2MKDK@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Rubrerythrin	-	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
k141_2197_1	1304885.AUEY01000014_gene3338	4.14e-256	715.0	COG0519@1|root,COG0519@2|Bacteria,1MU2A@1224|Proteobacteria,42M0I@68525|delta/epsilon subdivisions,2WJ6D@28221|Deltaproteobacteria,2MJ7G@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Catalyzes the synthesis of GMP from XMP	guaA	GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase,tRNA_Me_trans
k141_3915_1	1121441.AUCX01000013_gene1855	1.38e-56	195.0	COG0617@1|root,COG0617@2|Bacteria,1MU2X@1224|Proteobacteria,42N0S@68525|delta/epsilon subdivisions,2WM1Z@28221|Deltaproteobacteria,2M7VQ@213115|Desulfovibrionales	28221|Deltaproteobacteria	J	PFAM Polynucleotide adenylyltransferase region	cca	-	2.7.7.72	ko:K00974	ko03013,map03013	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016	-	-	-	HD,PolyA_pol,PolyA_pol_RNAbd
k141_3915_2	1265505.ATUG01000001_gene4731	8.59e-22	92.4	COG0505@1|root,COG0505@2|Bacteria,1MUB9@1224|Proteobacteria,42KZG@68525|delta/epsilon subdivisions,2WIQ5@28221|Deltaproteobacteria,2MIKI@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Belongs to the CarA family	carA	-	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_sm_chain,GATase
k141_3578_1	216596.RL1318	1.91e-44	178.0	COG0840@1|root,COG2972@1|root,COG0840@2|Bacteria,COG2972@2|Bacteria,1MU9B@1224|Proteobacteria,2TQR7@28211|Alphaproteobacteria,4BCHT@82115|Rhizobiaceae	28211|Alphaproteobacteria	NT	methyl-accepting chemotaxis protein	-	-	-	ko:K03406,ko:K05874	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal,PAS_3,dCache_1
k141_2493_1	177437.HRM2_38250	2.63e-69	228.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MIZ@68525|delta/epsilon subdivisions,2WIUX@28221|Deltaproteobacteria,2MJ42@213118|Desulfobacterales	28221|Deltaproteobacteria	T	PFAM ATP-binding region ATPase domain protein	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	CHASE5,HAMP,HATPase_c,HisKA,dCache_1,dCache_2
k141_4624_1	1116375.VEJY3_21376	4.35e-80	251.0	COG0246@1|root,COG0246@2|Bacteria,1MVZ7@1224|Proteobacteria,1RNIZ@1236|Gammaproteobacteria,1XV89@135623|Vibrionales	135623|Vibrionales	C	COG0246 Mannitol-1-phosphate altronate dehydrogenases	-	-	1.1.1.11	ko:K00007	ko00040,ko00051,ko01100,map00040,map00051,map01100	-	R00868,R05604	RC00085,RC00102	ko00000,ko00001,ko01000	-	-	-	Mannitol_dh,Mannitol_dh_C
k141_4624_2	1120931.KB893932_gene865	2.24e-59	192.0	COG0637@1|root,COG0637@2|Bacteria,1NF90@1224|Proteobacteria,1RNP8@1236|Gammaproteobacteria,1Y886@135625|Pasteurellales	135625|Pasteurellales	S	HAD-superfamily hydrolase, subfamily IA, variant 3	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
k141_4624_3	903818.KI912268_gene2388	3.84e-178	511.0	COG1012@1|root,COG1012@2|Bacteria,3Y2RN@57723|Acidobacteria	57723|Acidobacteria	C	Aldehyde dehydrogenase family	-	-	1.2.1.18,1.2.1.27	ko:K00140	ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200	M00013	R00705,R00706,R00922,R00935	RC00004,RC02723,RC02817	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
k141_2494_1	86416.Clopa_2229	2.44e-134	391.0	COG0473@1|root,COG0473@2|Bacteria,1TPEM@1239|Firmicutes,24A63@186801|Clostridia,36E5F@31979|Clostridiaceae	186801|Clostridia	C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate	leuB	-	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
k141_4938_1	1304885.AUEY01000003_gene514	5.41e-45	159.0	COG1061@1|root,COG1061@2|Bacteria,1QWMJ@1224|Proteobacteria,42NXF@68525|delta/epsilon subdivisions,2WJWA@28221|Deltaproteobacteria,2MHPY@213118|Desulfobacterales	28221|Deltaproteobacteria	L	type III restriction protein res subunit	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,ResIII
k141_4938_2	483216.BACEGG_03037	1.5e-81	258.0	COG0524@1|root,COG0524@2|Bacteria,4NIHI@976|Bacteroidetes,2FPRJ@200643|Bacteroidia,4AKX3@815|Bacteroidaceae	976|Bacteroidetes	G	Kinase, PfkB family	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
k141_4625_1	388467.A19Y_4397	1.33e-102	319.0	COG0469@1|root,COG0469@2|Bacteria,1G1IY@1117|Cyanobacteria,1H77F@1150|Oscillatoriales	1117|Cyanobacteria	G	Belongs to the pyruvate kinase family	pykF	GO:0003674,GO:0003824,GO:0004743,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PEP-utilizers,PK,PK_C
k141_4625_2	1304885.AUEY01000018_gene1099	2.2e-50	182.0	COG1466@1|root,COG1466@2|Bacteria,1RAEB@1224|Proteobacteria,42R0X@68525|delta/epsilon subdivisions,2WMQJ@28221|Deltaproteobacteria,2MJNX@213118|Desulfobacterales	28221|Deltaproteobacteria	L	DNA polymerase III, delta'	holA	-	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta
k141_3916_1	357804.Ping_0598	4.18e-52	176.0	2E2PJ@1|root,32XSE@2|Bacteria,1N1DP@1224|Proteobacteria,1SA0E@1236|Gammaproteobacteria,2QIVX@267894|Psychromonadaceae	1236|Gammaproteobacteria	S	Protein of unknown function (DUF3108)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3108
k141_3916_2	395494.Galf_0116	1.1e-36	145.0	COG1315@1|root,COG1352@1|root,COG2201@1|root,COG3829@1|root,COG5001@1|root,COG1315@2|Bacteria,COG1352@2|Bacteria,COG2201@2|Bacteria,COG3829@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Diguanylate cyclase	-	-	2.1.1.80,3.1.1.61	ko:K13924	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,CheR,CheR_N,EAL,GGDEF,PAS_3,PAS_9
k141_262_2	55601.VANGNB10_cI1374c	1.58e-282	779.0	COG2723@1|root,COG2723@2|Bacteria,1MWG6@1224|Proteobacteria,1RMM2@1236|Gammaproteobacteria,1XSV6@135623|Vibrionales	135623|Vibrionales	G	Belongs to the glycosyl hydrolase 1 family	bglA	-	3.2.1.86	ko:K01223	ko00010,ko00500,map00010,map00500	-	R00839,R05133,R05134	RC00049,RC00171,RC00714	ko00000,ko00001,ko01000	-	GT1	-	Glyco_hydro_1
k141_262_3	243277.VC_1557	8.43e-118	351.0	COG1609@1|root,COG1609@2|Bacteria,1N4ND@1224|Proteobacteria,1RNR5@1236|Gammaproteobacteria,1XVKJ@135623|Vibrionales	135623|Vibrionales	K	Transcriptional regulator, LacI family	-	-	-	ko:K02529,ko:K03487	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
k141_262_5	675815.VOA_001270	1.29e-218	617.0	COG1055@1|root,COG1055@2|Bacteria,1MUH8@1224|Proteobacteria,1RPSM@1236|Gammaproteobacteria,1XTNI@135623|Vibrionales	135623|Vibrionales	P	COG1055 Na H antiporter NhaD and related arsenite permeases	nhaD	-	-	-	-	-	-	-	-	-	-	-	CitMHS
k141_262_6	243277.VC_A1016	1.17e-36	129.0	2AWJ9@1|root,31NFW@2|Bacteria,1QK6V@1224|Proteobacteria,1TIA2@1236|Gammaproteobacteria,1XYQN@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_262_7	223926.28808179	5.52e-158	449.0	COG0583@1|root,COG0583@2|Bacteria,1MXXA@1224|Proteobacteria,1RREE@1236|Gammaproteobacteria,1XUTM@135623|Vibrionales	135623|Vibrionales	K	Transcriptional regulator	hdfR	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
k141_1514_1	55601.VANGNB10_cI2024	1.12e-207	591.0	COG0741@1|root,COG1388@1|root,COG0741@2|Bacteria,COG1388@2|Bacteria,1MWKE@1224|Proteobacteria,1RMFZ@1236|Gammaproteobacteria,1XUFQ@135623|Vibrionales	135623|Vibrionales	M	COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)	mltD	-	-	ko:K08307	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	LysM,SLT
k141_1514_2	55601.VANGNB10_cI2023	1.73e-129	373.0	COG0491@1|root,COG0491@2|Bacteria,1MU8Q@1224|Proteobacteria,1S22I@1236|Gammaproteobacteria,1XTAM@135623|Vibrionales	135623|Vibrionales	S	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid	gloB	GO:0003674,GO:0003824,GO:0004416,GO:0006518,GO:0006575,GO:0006749,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0016790,GO:0034641,GO:0043603,GO:0044237,GO:0051186,GO:0071704,GO:1901564	3.1.2.6	ko:K01069	ko00620,map00620	-	R01736	RC00004,RC00137	ko00000,ko00001,ko01000	-	-	-	HAGH_C,Lactamase_B
k141_1514_3	1348635.BBJY01000002_gene3420	3.84e-137	392.0	COG0500@1|root,COG2226@2|Bacteria,1QTWC@1224|Proteobacteria,1RS4G@1236|Gammaproteobacteria,1XTUC@135623|Vibrionales	135623|Vibrionales	Q	COG0500 SAM-dependent methyltransferases	yafS	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
k141_1514_4	29495.EA26_17285	2.34e-96	281.0	COG0328@1|root,COG0328@2|Bacteria,1RCZ1@1224|Proteobacteria,1S3YC@1236|Gammaproteobacteria,1XT8K@135623|Vibrionales	135623|Vibrionales	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhA	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576	3.1.26.4	ko:K03469	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_H
k141_1514_5	1219065.VPR01S_10_00440	3.62e-144	410.0	COG0847@1|root,COG0847@2|Bacteria,1MV8Z@1224|Proteobacteria,1RNHQ@1236|Gammaproteobacteria,1XTSV@135623|Vibrionales	135623|Vibrionales	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease	dnaQ	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	RNase_T
k141_1514_6	55601.VANGNB10_cI2019c	2.43e-175	503.0	COG2304@1|root,COG2304@2|Bacteria,1MVJ2@1224|Proteobacteria,1RMUF@1236|Gammaproteobacteria,1XSUT@135623|Vibrionales	135623|Vibrionales	S	von willebrand factor, type A	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_1514_8	1280001.BAOA01000081_gene3011	5.69e-177	496.0	COG0121@1|root,COG0121@2|Bacteria,1MU1J@1224|Proteobacteria,1RNEK@1236|Gammaproteobacteria,1XTCN@135623|Vibrionales	135623|Vibrionales	S	glutamine amidotransferase	yafJ	-	-	-	-	-	-	-	-	-	-	-	GATase_4
k141_1514_11	1187848.AJYQ01000069_gene2716	3.62e-140	398.0	COG0035@1|root,COG0035@2|Bacteria,1MV4N@1224|Proteobacteria,1RPBG@1236|Gammaproteobacteria,1XTNV@135623|Vibrionales	135623|Vibrionales	F	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate	upp	GO:0003674,GO:0003824,GO:0004845,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016757,GO:0016763,GO:0016772,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.4.2.9	ko:K00761	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000	-	-	-	UPRTase
k141_2211_1	316275.VSAL_I2357	2.25e-07	48.9	COG1925@1|root,COG1925@2|Bacteria,1N0CV@1224|Proteobacteria,1S9R2@1236|Gammaproteobacteria,1XXVH@135623|Vibrionales	135623|Vibrionales	G	phosphocarrier protein hpr	ptsH	GO:0003674,GO:0003824,GO:0005215,GO:0006810,GO:0008150,GO:0008643,GO:0008982,GO:0009401,GO:0015144,GO:0016740,GO:0016772,GO:0016773,GO:0022804,GO:0022857,GO:0034219,GO:0051179,GO:0051234,GO:0055085,GO:0071702	-	ko:K02784	ko02060,map02060	-	-	-	ko00000,ko00001,ko02000	8.A.8.1.1	-	-	PTS-HPr
k141_2211_2	1219065.VPR01S_02_00260	0.0	974.0	COG1080@1|root,COG1080@2|Bacteria,1MUT8@1224|Proteobacteria,1RN6R@1236|Gammaproteobacteria,1XSKW@135623|Vibrionales	135623|Vibrionales	G	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)	ptsI	-	2.7.3.9	ko:K08483	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	8.A.7	-	-	PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C
k141_2211_4	675815.VOA_000674	1.56e-156	452.0	COG0654@1|root,COG0654@2|Bacteria,1MU6I@1224|Proteobacteria,1RND5@1236|Gammaproteobacteria,1XU6J@135623|Vibrionales	135623|Vibrionales	CH	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	ubiF	-	-	ko:K03184	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R06146,R08775	RC01254	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,FAD_binding_3,SE
k141_2211_6	223926.28805718	2.71e-225	625.0	COG1702@1|root,COG1702@2|Bacteria,1MVDV@1224|Proteobacteria,1RP2Y@1236|Gammaproteobacteria,1XVDI@135623|Vibrionales	135623|Vibrionales	T	Phosphate starvation-inducible protein PhoH	ybeZ	-	-	ko:K06217	-	-	-	-	ko00000	-	-	-	PhoH
k141_2211_7	870967.VIS19158_23205	3.08e-82	246.0	COG0319@1|root,COG0319@2|Bacteria,1MZ67@1224|Proteobacteria,1S6BS@1236|Gammaproteobacteria,1XWWW@135623|Vibrionales	135623|Vibrionales	J	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA	ybeY	-	-	ko:K07042	-	-	-	-	ko00000,ko03009	-	-	-	UPF0054
k141_2211_8	55601.VANGNB10_cI0834c	1.09e-165	468.0	COG4535@1|root,COG4535@2|Bacteria,1QTU8@1224|Proteobacteria,1RMKX@1236|Gammaproteobacteria,1XT0H@135623|Vibrionales	135623|Vibrionales	P	Mg2 and Co2 transporter CorC	corC	GO:0001897,GO:0001906,GO:0001907,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0009405,GO:0009987,GO:0016020,GO:0019835,GO:0019836,GO:0031640,GO:0035821,GO:0044003,GO:0044004,GO:0044179,GO:0044364,GO:0044403,GO:0044419,GO:0044464,GO:0044764,GO:0051701,GO:0051704,GO:0051715,GO:0051801,GO:0051817,GO:0051818,GO:0051883,GO:0052331,GO:0071944	-	ko:K06189	-	-	-	-	ko00000,ko02000	9.A.40.1.2	-	-	CBS,CorC_HlyC
k141_2211_9	945550.VISI1226_03230	3.35e-224	634.0	COG0815@1|root,COG0815@2|Bacteria,1MUBU@1224|Proteobacteria,1RM8M@1236|Gammaproteobacteria,1XSXY@135623|Vibrionales	135623|Vibrionales	M	Transfers the fatty acyl group on membrane lipoproteins	lnt	GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564	-	ko:K03820	-	-	-	-	ko00000,ko01000	-	GT2	-	CN_hydrolase
k141_2211_10	672.VV93_v1c08490	5.43e-69	212.0	COG2888@1|root,COG2888@2|Bacteria,1P9T7@1224|Proteobacteria,1SAPZ@1236|Gammaproteobacteria,1XU0U@135623|Vibrionales	135623|Vibrionales	J	Zinc-ribbon containing domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF1451
k141_2211_11	55601.VANGNB10_cI0831c	0.0	1530.0	COG0495@1|root,COG0495@2|Bacteria,1MV47@1224|Proteobacteria,1RP14@1236|Gammaproteobacteria,1XTP8@135623|Vibrionales	135623|Vibrionales	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
k141_2211_12	1136163.M565_ctg1P1820	3.91e-63	201.0	COG2980@1|root,COG2980@2|Bacteria,1NGPX@1224|Proteobacteria,1SGKQ@1236|Gammaproteobacteria,1Y2PX@135623|Vibrionales	135623|Vibrionales	M	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane	lptE	-	-	ko:K03643	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	LptE
k141_2211_13	1219065.VPR01S_02_00150	3.72e-139	405.0	COG1466@1|root,COG1466@2|Bacteria,1MWYT@1224|Proteobacteria,1RQRE@1236|Gammaproteobacteria,1XUE0@135623|Vibrionales	135623|Vibrionales	L	DNA polymerase III, delta subunit	holA	-	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delt_C,DNA_pol3_delta
k141_2211_14	1238450.VIBNISOn1_790089	7.57e-53	167.0	COG0799@1|root,COG0799@2|Bacteria,1MZEF@1224|Proteobacteria,1S8W3@1236|Gammaproteobacteria,1XXWJ@135623|Vibrionales	135623|Vibrionales	J	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation	rsfS	-	-	ko:K09710	-	-	-	-	ko00000,ko03009	-	-	-	RsfS
k141_2211_15	1348635.BBJY01000012_gene1154	2.51e-93	273.0	COG1576@1|root,COG1576@2|Bacteria,1R9Z2@1224|Proteobacteria,1S1ZY@1236|Gammaproteobacteria,1XSIT@135623|Vibrionales	135623|Vibrionales	J	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA	rlmH	-	2.1.1.177	ko:K00783	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SPOUT_MTase
k141_2211_16	1219065.VPR01S_02_00120	0.0	1001.0	COG0768@1|root,COG0768@2|Bacteria,1MV8C@1224|Proteobacteria,1RN9H@1236|Gammaproteobacteria,1XTJ2@135623|Vibrionales	135623|Vibrionales	M	Catalyzes cross-linking of the peptidoglycan cell wall	mrdA	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	PBP_dimer,Transpeptidase
k141_2211_17	55601.VANGNB10_cI0825c	1.73e-224	624.0	COG0772@1|root,COG0772@2|Bacteria,1MUK3@1224|Proteobacteria,1RMEJ@1236|Gammaproteobacteria,1XSC3@135623|Vibrionales	135623|Vibrionales	M	Peptidoglycan polymerase that is essential for cell wall elongation	mrdB	-	-	ko:K05837	-	-	-	-	ko00000,ko03036	-	-	-	FTSW_RODA_SPOVE
k141_2211_18	1348635.BBJY01000012_gene1157	6.97e-77	243.0	COG0797@1|root,COG0797@2|Bacteria,1MZ8S@1224|Proteobacteria,1RMCG@1236|Gammaproteobacteria,1XSTT@135623|Vibrionales	135623|Vibrionales	M	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides	rlpA	-	-	ko:K03642	-	-	-	-	ko00000	-	-	-	DPBB_1,SPOR
k141_2211_19	870967.VIS19158_23265	1.03e-237	659.0	COG1686@1|root,COG1686@2|Bacteria,1MUU7@1224|Proteobacteria,1RMJA@1236|Gammaproteobacteria,1XSFX@135623|Vibrionales	135623|Vibrionales	M	Belongs to the peptidase S11 family	dacA	-	3.4.16.4	ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	PBP5_C,Peptidase_S11
k141_2211_20	945550.VISI1226_03175	1.31e-56	176.0	COG2921@1|root,COG2921@2|Bacteria,1RGV5@1224|Proteobacteria,1S61Y@1236|Gammaproteobacteria,1XXUJ@135623|Vibrionales	135623|Vibrionales	S	Belongs to the UPF0250 family	ybeD	-	-	ko:K09158	-	-	-	-	ko00000	-	-	-	DUF493
k141_2211_21	1280001.BAOA01000003_gene3721	7.61e-115	333.0	COG0321@1|root,COG0321@2|Bacteria,1MU6A@1224|Proteobacteria,1RMXQ@1236|Gammaproteobacteria,1XT77@135623|Vibrionales	135623|Vibrionales	H	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate	lipB	GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0016874,GO:0016879,GO:0016979,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0071704,GO:0072330,GO:0140096,GO:1901360,GO:1901362,GO:1901564,GO:1901576	2.3.1.181	ko:K03801	ko00785,ko01100,map00785,map01100	-	R07766,R07769	RC00039,RC00992,RC02867	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB
k141_2211_23	243277.VC_0942	1.3e-52	167.0	2AW92@1|root,31N4D@2|Bacteria,1QJVU@1224|Proteobacteria,1THXF@1236|Gammaproteobacteria,1XXTJ@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_2211_24	243277.VC_0941	1.26e-280	770.0	COG0112@1|root,COG0112@2|Bacteria,1MUIS@1224|Proteobacteria,1RMHQ@1236|Gammaproteobacteria,1XTKA@135623|Vibrionales	135623|Vibrionales	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	GO:0001505,GO:0003674,GO:0003824,GO:0004372,GO:0006082,GO:0006520,GO:0006544,GO:0006545,GO:0006730,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016742,GO:0017144,GO:0019752,GO:0042133,GO:0042136,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
k141_3579_1	443143.GM18_3828	1.32e-66	236.0	COG2982@1|root,COG2982@2|Bacteria,1MUME@1224|Proteobacteria,42M50@68525|delta/epsilon subdivisions,2WIP4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Domain of Unknown Function (DUF748)	-	-	-	-	-	-	-	-	-	-	-	-	DUF748
k141_3579_3	555088.DealDRAFT_2378	4.39e-16	78.6	COG2113@1|root,COG2113@2|Bacteria,1TP82@1239|Firmicutes,24C2M@186801|Clostridia	186801|Clostridia	E	of ABC-type glycine betaine transport system	-	-	-	ko:K02002,ko:K03406	ko02010,ko02020,ko02030,map02010,map02020,map02030	M00208	-	-	ko00000,ko00001,ko00002,ko02000,ko02035	3.A.1.12	-	-	MCPsignal,OpuAC
k141_4940_1	439235.Dalk_1755	6.13e-103	317.0	COG3829@1|root,COG3829@2|Bacteria,1MXSB@1224|Proteobacteria,42PHW@68525|delta/epsilon subdivisions,2WJSS@28221|Deltaproteobacteria,2MHWS@213118|Desulfobacterales	28221|Deltaproteobacteria	KT	Sigma-54 interaction domain	-	-	-	-	-	-	-	-	-	-	-	-	Sigma54_activat
k141_4626_1	1078085.HMPREF1210_03093	1.27e-188	539.0	COG3048@1|root,COG3048@2|Bacteria,1TPAH@1239|Firmicutes,4HANC@91061|Bacilli,26CZN@186818|Planococcaceae	91061|Bacilli	E	Belongs to the serine threonine dehydratase family. DsdA subfamily	dsdA	-	4.3.1.18	ko:K01753	ko00260,map00260	-	R00221	RC02600	ko00000,ko00001,ko01000	-	-	-	PALP
k141_263_2	1232437.KL661961_gene2963	2.3e-148	432.0	COG1916@1|root,COG1916@2|Bacteria,1MWJ0@1224|Proteobacteria,42P2H@68525|delta/epsilon subdivisions,2WJQM@28221|Deltaproteobacteria,2MI76@213118|Desulfobacterales	28221|Deltaproteobacteria	S	TIGRFAM TraB family protein	-	-	-	-	-	-	-	-	-	-	-	-	TraB
k141_3580_1	1121422.AUMW01000029_gene39	5.15e-186	537.0	COG0043@1|root,COG0043@2|Bacteria,1TQ6V@1239|Firmicutes,248WY@186801|Clostridia,261BW@186807|Peptococcaceae	186801|Clostridia	H	Belongs to the UbiD family	-	-	4.1.1.61,4.1.1.98	ko:K03182,ko:K16239	ko00130,ko00627,ko01100,ko01110,ko01120,map00130,map00627,map01100,map01110,map01120	M00117	R01238,R04985,R04986	RC00391	ko00000,ko00001,ko00002,ko01000	-	-	-	UbiD
k141_5341_5	1408813.AYMG01000039_gene2301	3.31e-20	90.9	2C0BR@1|root,32Z3H@2|Bacteria,4NVDW@976|Bacteroidetes,1IU2Z@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF4255)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4255
k141_5341_7	1209072.ALBT01000068_gene182	2.02e-122	371.0	COG0464@1|root,COG0464@2|Bacteria,1NF48@1224|Proteobacteria,1RQNE@1236|Gammaproteobacteria,1FHUC@10|Cellvibrio	1236|Gammaproteobacteria	O	ATPase family associated with various cellular activities (AAA)	-	-	-	-	-	-	-	-	-	-	-	-	AAA
k141_5341_8	1120966.AUBU01000020_gene288	2.7e-42	158.0	COG3177@1|root,COG3177@2|Bacteria,4NR8T@976|Bacteroidetes,47QX8@768503|Cytophagia	976|Bacteroidetes	KLT	Domain of unknown function (DUF4157)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4157
k141_5341_12	1117318.PRUB_11871	2.45e-24	103.0	COG3177@1|root,COG3177@2|Bacteria,1RJSD@1224|Proteobacteria,1S9AR@1236|Gammaproteobacteria,2Q4MH@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	S	Domain of unknown function (DUF4157)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4157
k141_5341_15	1430440.MGMSRv2_1935	8.15e-18	86.3	COG0745@1|root,COG0745@2|Bacteria,1MZQA@1224|Proteobacteria	1224|Proteobacteria	T	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	ko:K02483,ko:K07657	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
k141_5341_16	1117318.PRUB_06770	7.61e-78	239.0	COG2801@1|root,COG2801@2|Bacteria,1MZ45@1224|Proteobacteria,1RSNX@1236|Gammaproteobacteria,2Q00G@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	L	COG2801 Transposase and inactivated derivatives	ylbG	-	-	-	-	-	-	-	-	-	-	-	HTH_29,rve,rve_2,rve_3
k141_5341_18	1238450.VIBNISOn1_560052	5.06e-78	236.0	COG1846@1|root,COG1846@2|Bacteria,1RF8X@1224|Proteobacteria,1S4RW@1236|Gammaproteobacteria,1XX10@135623|Vibrionales	135623|Vibrionales	K	COG1846 Transcriptional regulators	-	-	-	-	-	-	-	-	-	-	-	-	MarR
k141_5341_19	29495.EA26_06800	4.35e-38	132.0	COG0735@1|root,COG0735@2|Bacteria,1QJWN@1224|Proteobacteria,1THYF@1236|Gammaproteobacteria,1XXWI@135623|Vibrionales	135623|Vibrionales	P	belongs to the Fur family	VV2111	-	-	-	-	-	-	-	-	-	-	-	-
k141_5341_20	675813.VIB_001375	3.85e-130	372.0	COG0491@1|root,COG0491@2|Bacteria,1MUDN@1224|Proteobacteria,1RMMG@1236|Gammaproteobacteria,1XU1B@135623|Vibrionales	135623|Vibrionales	S	COG0491 Zn-dependent hydrolases, including glyoxylases	ycbL	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
k141_5341_21	672.VV93_v1c18840	4.14e-117	338.0	COG0807@1|root,COG0807@2|Bacteria,1MWZR@1224|Proteobacteria,1RMFX@1236|Gammaproteobacteria,1XU21@135623|Vibrionales	135623|Vibrionales	F	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate	ribA	GO:0003674,GO:0003824,GO:0003933,GO:0003935,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017144,GO:0018130,GO:0019238,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	3.5.4.25	ko:K01497	ko00740,ko00790,ko01100,ko01110,ko02024,map00740,map00790,map01100,map01110,map02024	M00125	R00425	RC00293,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_cyclohydro2
k141_5341_25	1219076.N646_1013	0.0	1487.0	COG0188@1|root,COG0188@2|Bacteria,1MUGG@1224|Proteobacteria,1RN03@1236|Gammaproteobacteria,1XSUD@135623|Vibrionales	135623|Vibrionales	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
k141_5341_26	243277.VC_1257	7.4e-139	396.0	COG2227@1|root,COG2227@2|Bacteria,1MU89@1224|Proteobacteria,1RMV7@1236|Gammaproteobacteria,1XSEV@135623|Vibrionales	135623|Vibrionales	H	O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway	ubiG	GO:0003674,GO:0003824,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008689,GO:0008757,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016741,GO:0032259,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0061542,GO:0071704,GO:1901576,GO:1901661,GO:1901663	2.1.1.222,2.1.1.64	ko:K00568	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04988,R05614,R08769,R08781	RC00003,RC00392,RC01895	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_23
k141_5341_27	1051646.VITU9109_23090	3.8e-273	764.0	COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,1RMPV@1236|Gammaproteobacteria,1XTXI@135623|Vibrionales	135623|Vibrionales	F	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides	nrdA	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	ATP-cone,Ribonuc_red_lgC,Ribonuc_red_lgN
k141_2987_1	658086.HMPREF0994_02091	1.29e-135	425.0	COG3664@1|root,COG4977@1|root,COG3664@2|Bacteria,COG4977@2|Bacteria,1TQGI@1239|Firmicutes,2490Q@186801|Clostridia,27IW2@186928|unclassified Lachnospiraceae	186801|Clostridia	K	Glycosyl hydrolases family 39	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,Cupin_2,Glyco_hydro_39,HTH_18
k141_2987_2	658086.HMPREF0994_02086	6.46e-53	170.0	COG1082@1|root,COG1082@2|Bacteria,1V67Z@1239|Firmicutes,24I3Q@186801|Clostridia,27Q5Q@186928|unclassified Lachnospiraceae	186801|Clostridia	G	Xylose isomerase domain protein TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_2987_3	658086.HMPREF0994_02087	7.98e-180	507.0	COG1082@1|root,COG1082@2|Bacteria,1TZBT@1239|Firmicutes,24813@186801|Clostridia,27K6V@186928|unclassified Lachnospiraceae	186801|Clostridia	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
k141_2987_4	1203606.HMPREF1526_01163	2.35e-181	513.0	COG0673@1|root,COG0673@2|Bacteria,1TQFW@1239|Firmicutes,24BIG@186801|Clostridia,36EXZ@31979|Clostridiaceae	186801|Clostridia	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
k141_2987_5	1410628.JNKS01000018_gene799	9.12e-161	457.0	COG1082@1|root,COG1082@2|Bacteria,1TPJT@1239|Firmicutes,24A6G@186801|Clostridia,27KAW@186928|unclassified Lachnospiraceae	186801|Clostridia	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2,AP_endonuc_2_N
k141_2987_6	1235802.C823_01998	1.27e-222	619.0	COG0673@1|root,COG0673@2|Bacteria,1TQ72@1239|Firmicutes,24XW6@186801|Clostridia	186801|Clostridia	S	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
k141_2987_8	1219065.VPR01S_19_00870	7.57e-154	461.0	COG4533@1|root,COG4533@2|Bacteria,1N2NK@1224|Proteobacteria,1RP2Z@1236|Gammaproteobacteria,1XVAS@135623|Vibrionales	135623|Vibrionales	K	transport system, periplasmic component	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_5,SgrR_N
k141_2987_9	338966.Ppro_1974	5.35e-285	793.0	COG0446@1|root,COG0607@1|root,COG0446@2|Bacteria,COG0607@2|Bacteria,1NR3M@1224|Proteobacteria,42N3G@68525|delta/epsilon subdivisions,2WIS9@28221|Deltaproteobacteria,43TPE@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Pyr_redox_dim,Rhodanese
k141_2987_10	331678.Cphamn1_1080	6.26e-68	219.0	COG1237@1|root,COG1237@2|Bacteria	2|Bacteria	S	Metallo-beta-lactamase superfamily	-	-	2.5.1.105	ko:K06897	ko00790,map00790	-	R10339	RC00121	ko00000,ko00001,ko01000	-	-	-	Lactamase_B
k141_2987_11	1379281.AVAG01000014_gene1434	6.08e-37	128.0	COG1433@1|root,COG1433@2|Bacteria,1MZTM@1224|Proteobacteria,42U2B@68525|delta/epsilon subdivisions,2WQAQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM Dinitrogenase iron-molybdenum cofactor biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	Nitro_FeMo-Co
k141_2987_12	747365.Thena_1652	9.27e-106	316.0	COG1149@1|root,COG1149@2|Bacteria,1TQI9@1239|Firmicutes,2484J@186801|Clostridia,42FZ8@68295|Thermoanaerobacterales	186801|Clostridia	C	PFAM Cobyrinic acid a,c-diamide synthase	-	-	-	-	-	-	-	-	-	-	-	-	CbiA,Fer4
k141_2987_13	1304885.AUEY01000016_gene3040	1.87e-84	261.0	COG1149@1|root,COG1149@2|Bacteria,1NCD9@1224|Proteobacteria,42PHV@68525|delta/epsilon subdivisions,2WKDZ@28221|Deltaproteobacteria,2MIUE@213118|Desulfobacterales	28221|Deltaproteobacteria	C	CobQ CobB MinD ParA nucleotide binding domain	-	-	-	-	-	-	-	-	-	-	-	-	CbiA,Fer4
k141_2987_14	398767.Glov_1686	1.12e-33	120.0	COG1433@1|root,COG1433@2|Bacteria,1MZ77@1224|Proteobacteria,42U3G@68525|delta/epsilon subdivisions,2WQ5N@28221|Deltaproteobacteria,43VC1@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Dinitrogenase iron-molybdenum cofactor	-	-	-	-	-	-	-	-	-	-	-	-	Nitro_FeMo-Co
k141_2987_16	439235.Dalk_2260	4.98e-22	94.0	COG1433@1|root,COG1433@2|Bacteria,1NKUY@1224|Proteobacteria,42XKV@68525|delta/epsilon subdivisions,2WSWQ@28221|Deltaproteobacteria,2MM9Y@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Dinitrogenase iron-molybdenum cofactor	-	-	-	-	-	-	-	-	-	-	-	-	Nitro_FeMo-Co
k141_2987_17	338963.Pcar_1580	1.17e-193	553.0	COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,42MFH@68525|delta/epsilon subdivisions,2WIRW@28221|Deltaproteobacteria,43TYZ@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	PFAM sigma-54 factor interaction domain-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,PAS_4,PAS_9,Sigma54_activat
k141_2987_18	1453501.JELR01000002_gene63	4.33e-81	243.0	COG0783@1|root,COG0783@2|Bacteria,1RAC5@1224|Proteobacteria,1S2H7@1236|Gammaproteobacteria,466DT@72275|Alteromonadaceae	1236|Gammaproteobacteria	P	Belongs to the Dps family	dps	-	-	ko:K04047	-	-	-	-	ko00000,ko03036	-	-	-	Ferritin
k141_5342_1	701176.VIBRN418_06296	1.95e-190	540.0	COG0246@1|root,COG0246@2|Bacteria,1MVZ7@1224|Proteobacteria,1RQX5@1236|Gammaproteobacteria,1XUJB@135623|Vibrionales	135623|Vibrionales	C	Mannitol dehydrogenase C-terminal domain	-	-	1.1.1.58	ko:K00041	ko00040,ko01100,map00040,map01100	M00631	R02555	RC00085	ko00000,ko00001,ko00002,ko01000	-	-	-	Mannitol_dh,Mannitol_dh_C
k141_2688_1	313628.LNTAR_15977	2.76e-267	759.0	COG0143@1|root,COG0143@2|Bacteria	2|Bacteria	J	methionyl-tRNA aminoacylation	metG	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g,tRNA_bind
k141_2688_2	489825.LYNGBM3L_45360	6.63e-07	57.4	COG0566@1|root,COG0566@2|Bacteria,1G18R@1117|Cyanobacteria,1H8E4@1150|Oscillatoriales	1117|Cyanobacteria	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	spoU	-	-	ko:K03437	-	-	-	-	ko00000,ko03016	-	-	-	SpoU_methylase,SpoU_sub_bind
k141_2688_3	1121405.dsmv_0441	2.8e-32	120.0	COG0101@1|root,COG0101@2|Bacteria,1MUYI@1224|Proteobacteria,42RTC@68525|delta/epsilon subdivisions,2WNQ6@28221|Deltaproteobacteria,2MJMQ@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
k141_2988_1	1304885.AUEY01000011_gene1735	3.01e-144	451.0	COG1924@1|root,COG3580@1|root,COG3581@1|root,COG1924@2|Bacteria,COG3580@2|Bacteria,COG3581@2|Bacteria,1PKG6@1224|Proteobacteria,42MY4@68525|delta/epsilon subdivisions,2WJFI@28221|Deltaproteobacteria,2MIP0@213118|Desulfobacterales	68525|delta/epsilon subdivisions	I	BadF BadG BcrA BcrD	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG,DUF2229
k141_2690_1	1304885.AUEY01000082_gene2154	3.61e-193	558.0	COG0243@1|root,COG0243@2|Bacteria,1NR6J@1224|Proteobacteria,42NEV@68525|delta/epsilon subdivisions,2WJD0@28221|Deltaproteobacteria,2MHX6@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Molybdopterin oxidoreductase Fe4S4 domain	-	-	-	-	-	-	-	-	-	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
k141_2691_1	1304885.AUEY01000026_gene3563	3.28e-12	65.9	COG1674@1|root,COG1674@2|Bacteria,1MVPI@1224|Proteobacteria,42N4X@68525|delta/epsilon subdivisions,2WIPR@28221|Deltaproteobacteria,2MI69@213118|Desulfobacterales	28221|Deltaproteobacteria	D	DNA segregation ATPase, FtsK SpoIIIE family	ftsK	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
k141_2989_1	595494.Tola_2992	5.45e-49	157.0	COG1440@1|root,COG1440@2|Bacteria,1MZHX@1224|Proteobacteria,1S94Q@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	Phosphotransferase System	Z012_08190	-	2.7.1.196,2.7.1.205	ko:K02760	ko00500,ko02060,map00500,map02060	M00275	R11170,R11172	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.3.2	-	-	PTS_IIB
k141_5343_1	675806.VII_002821	4.74e-64	246.0	COG3170@1|root,COG3170@2|Bacteria,1MXV7@1224|Proteobacteria,1RMM5@1236|Gammaproteobacteria,1XUV6@135623|Vibrionales	135623|Vibrionales	NU	COG3170 Tfp pilus assembly protein FimV	-	-	-	ko:K08086	-	-	-	-	ko00000	-	-	-	-
k141_2692_1	675813.VIB_002233	1.44e-42	150.0	COG3395@1|root,COG3395@2|Bacteria,1MW4G@1224|Proteobacteria,1RN8I@1236|Gammaproteobacteria,1XV5M@135623|Vibrionales	135623|Vibrionales	S	Putative nucleotide-binding of sugar-metabolising enzyme	-	-	2.7.1.217	ko:K21948	-	-	R11706,R11707	-	ko00000,ko01000	-	-	-	DUF1357_C,DUF1537
k141_2692_2	316275.VSAL_II0104	7.27e-120	351.0	COG2084@1|root,COG2084@2|Bacteria,1MUD0@1224|Proteobacteria,1RQXA@1236|Gammaproteobacteria,1XT03@135623|Vibrionales	135623|Vibrionales	I	NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase	-	-	1.1.1.411	ko:K08319	-	-	-	-	ko00000,ko01000	-	-	-	NAD_binding_11,NAD_binding_2
k141_2693_1	649639.Bcell_0690	7.67e-10	68.2	2DPRW@1|root,COG2273@1|root,COG3767@1|root,COG5498@1|root,3334N@2|Bacteria,COG2273@2|Bacteria,COG3767@2|Bacteria,COG5498@2|Bacteria,1TR5U@1239|Firmicutes,4HB9D@91061|Bacilli,1ZFAG@1386|Bacillus	91061|Bacilli	G	Glycoside hydrolase family 16	-	-	-	-	-	-	-	-	-	-	-	-	CBM_4_9,Glyco_hydro_16,Gram_pos_anchor,SLH
k141_1000_1	1051646.VITU9109_03700	4.08e-91	272.0	COG0212@1|root,COG0212@2|Bacteria,1MZG0@1224|Proteobacteria,1S612@1236|Gammaproteobacteria,1XT1H@135623|Vibrionales	135623|Vibrionales	H	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family	ygfA	-	6.3.3.2	ko:K01934	ko00670,ko01100,map00670,map01100	-	R02301	RC00183	ko00000,ko00001,ko01000	-	-	-	5-FTHF_cyc-lig
k141_1000_4	1348635.BBJY01000002_gene3462	2.36e-265	733.0	COG4664@1|root,COG4664@2|Bacteria,1R4MZ@1224|Proteobacteria,1RMR6@1236|Gammaproteobacteria,1XUVW@135623|Vibrionales	135623|Vibrionales	Q	COG4664 TRAP-type mannitol chloroaromatic compound transport system, large permease component	-	-	-	-	-	-	-	-	-	-	-	-	DctM
k141_1000_5	1348635.BBJY01000002_gene3463	1.7e-90	271.0	COG4665@1|root,COG4665@2|Bacteria,1RDP0@1224|Proteobacteria,1S4A5@1236|Gammaproteobacteria,1XUZC@135623|Vibrionales	135623|Vibrionales	Q	Tripartite ATP-independent periplasmic transporter DctQ	-	-	-	-	-	-	-	-	-	-	-	-	DctQ
k141_1000_6	1348635.BBJY01000002_gene3464	1.45e-193	542.0	COG1638@1|root,COG1638@2|Bacteria,1QWNV@1224|Proteobacteria,1RQXG@1236|Gammaproteobacteria,1XWSV@135623|Vibrionales	135623|Vibrionales	G	COG4663 TRAP-type mannitol chloroaromatic compound transport system, periplasmic component	-	-	-	-	-	-	-	-	-	-	-	-	DctP
k141_2694_1	944564.HMPREF9200_1553	2.62e-103	316.0	COG0826@1|root,COG0826@2|Bacteria,1TPRE@1239|Firmicutes,4H25V@909932|Negativicutes	909932|Negativicutes	O	Peptidase U32	yhbU_2	-	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_U32,Peptidase_U32_C
k141_5344_1	1225785.CM001983_gene413	6.2e-31	110.0	COG0847@1|root,COG0847@2|Bacteria,1N05B@1224|Proteobacteria,1S6XV@1236|Gammaproteobacteria,2JEEG@204037|Dickeya	1236|Gammaproteobacteria	L	CRISPR-associated protein (Cas_Cas2CT1978)	ygbF	GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0034641,GO:0043170,GO:0043570,GO:0043571,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0051276,GO:0071704,GO:0071840,GO:0090304,GO:1901360	-	ko:K09951	-	-	-	-	ko00000,ko02048	-	-	-	Cas_Cas2CT1978
k141_5344_2	298386.PBPRC0034	5.11e-181	508.0	COG1518@1|root,COG1518@2|Bacteria,1MUXH@1224|Proteobacteria,1RP48@1236|Gammaproteobacteria,1XY4W@135623|Vibrionales	135623|Vibrionales	L	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette	cas1	-	-	ko:K15342	-	-	-	-	ko00000,ko02048,ko03400	-	-	-	Cas_Cas1
k141_5344_3	298386.PBPRC0035	1.11e-33	127.0	2AAIB@1|root,30ZVG@2|Bacteria,1PMUT@1224|Proteobacteria,1SXC7@1236|Gammaproteobacteria,1Y06U@135623|Vibrionales	135623|Vibrionales	S	CRISPR-associated protein Cse1 (CRISPR_cse1)	-	-	-	ko:K19123	-	-	-	-	ko00000,ko02048	-	-	-	CRISPR_Cse1
k141_2695_1	994573.T472_0203970	6.99e-97	300.0	COG2414@1|root,COG2414@2|Bacteria,1TPT9@1239|Firmicutes,2481Q@186801|Clostridia,36FZW@31979|Clostridiaceae	186801|Clostridia	C	Aldehyde ferredoxin oxidoreductase	aor	-	1.2.7.5	ko:K03738	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00309	R08571	RC00242	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS09915	AFOR_C,AFOR_N
k141_1001_2	1232437.KL662011_gene1509	7.73e-39	145.0	COG0018@1|root,COG0018@2|Bacteria,1MU4J@1224|Proteobacteria,42MTY@68525|delta/epsilon subdivisions,2WKII@28221|Deltaproteobacteria,2MI2W@213118|Desulfobacterales	28221|Deltaproteobacteria	J	TIGRFAM arginyl-tRNA synthetase	argS	GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	iAF987.Gmet_1434	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
k141_2696_1	1232437.KL661965_gene3215	8.94e-141	419.0	COG1884@1|root,COG2185@1|root,COG1884@2|Bacteria,COG2185@2|Bacteria,1MUXX@1224|Proteobacteria,42P03@68525|delta/epsilon subdivisions,2WIPY@28221|Deltaproteobacteria,2MICJ@213118|Desulfobacterales	28221|Deltaproteobacteria	I	TIGRFAM methylmalonyl-CoA mutase, large subunit	-	-	5.4.99.2	ko:K01847	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,MM_CoA_mutase
k141_2697_1	1265505.ATUG01000002_gene1690	4.1e-31	115.0	COG1392@1|root,COG1392@2|Bacteria	2|Bacteria	P	Protein of unknown function DUF47	-	-	-	ko:K07220	-	-	-	-	ko00000	-	-	-	PhoU_div
k141_2697_2	391009.Tmel_0789	7.42e-23	97.8	COG0306@1|root,COG0306@2|Bacteria,2GCK4@200918|Thermotogae	200918|Thermotogae	P	PFAM phosphate transporter	-	-	-	ko:K03306	-	-	-	-	ko00000	2.A.20	-	-	PHO4
k141_5347_20	573061.Clocel_0969	0.0	1262.0	COG2244@1|root,COG2244@2|Bacteria,1UZBQ@1239|Firmicutes,24C4B@186801|Clostridia,36FZB@31979|Clostridiaceae	186801|Clostridia	S	polysaccharide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_5347_21	931276.Cspa_c03660	3.16e-123	367.0	COG0463@1|root,COG0463@2|Bacteria,1UE0C@1239|Firmicutes,249GE@186801|Clostridia,36HGZ@31979|Clostridiaceae	186801|Clostridia	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
k141_5347_22	1304885.AUEY01000033_gene1920	1.47e-23	102.0	COG3437@1|root,COG3437@2|Bacteria,1P1A3@1224|Proteobacteria,42R7R@68525|delta/epsilon subdivisions,2WMT0@28221|Deltaproteobacteria,2MJMX@213118|Desulfobacterales	28221|Deltaproteobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,HATPase_c,HisKA,PAS,Response_reg
k141_5347_23	349520.PPE_03727	3.24e-99	300.0	COG1215@1|root,COG1215@2|Bacteria,1TRYI@1239|Firmicutes,4HUE2@91061|Bacilli,26W7H@186822|Paenibacillaceae	91061|Bacilli	M	involved in cell wall biogenesis	kfoC	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
k141_5347_24	573061.Clocel_0962	2.64e-159	459.0	COG0438@1|root,COG0438@2|Bacteria,1UYSU@1239|Firmicutes,24EIH@186801|Clostridia,36HKX@31979|Clostridiaceae	186801|Clostridia	M	Glycosyl transferases group 1	-	-	2.4.1.11	ko:K16150	ko00500,ko01100,map00500,map01100	-	R00292	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT4	-	Glyco_transf_4,Glycos_transf_1
k141_5347_25	931276.Cspa_c03600	4.12e-57	200.0	COG2244@1|root,COG2244@2|Bacteria,1VPUV@1239|Firmicutes,24CH7@186801|Clostridia,36GWF@31979|Clostridiaceae	186801|Clostridia	S	polysaccharide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt
k141_5347_26	931276.Cspa_c03660	9.59e-120	358.0	COG0463@1|root,COG0463@2|Bacteria,1UE0C@1239|Firmicutes,249GE@186801|Clostridia,36HGZ@31979|Clostridiaceae	186801|Clostridia	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
k141_5347_27	1123020.AUIE01000011_gene1293	2.03e-24	108.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1YIWT@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF,GAF_2,GGDEF,MASE3,PAS,PAS_3,PAS_4,PAS_9,Response_reg
k141_5347_29	1121423.JONT01000008_gene722	4.49e-102	311.0	COG4632@1|root,COG4632@2|Bacteria,1TP2R@1239|Firmicutes,249PA@186801|Clostridia	186801|Clostridia	G	Exopolysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	CW_binding_2,Cu_amine_oxidN1,NAGPA
k141_5347_30	1347392.CCEZ01000043_gene83	3.03e-79	247.0	COG0834@1|root,COG0834@2|Bacteria,1TT16@1239|Firmicutes,24CEZ@186801|Clostridia,36EZP@31979|Clostridiaceae	186801|Clostridia	ET	Belongs to the bacterial solute-binding protein 3 family	artP	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
k141_5347_32	1286171.EAL2_c17450	2.24e-103	306.0	COG0765@1|root,COG0765@2|Bacteria,1TPM3@1239|Firmicutes,248UY@186801|Clostridia,25W65@186806|Eubacteriaceae	186801|Clostridia	P	ABC transporter, permease protein	-	-	-	ko:K02029,ko:K02030,ko:K10040	ko02010,map02010	M00228,M00236	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3	-	-	BPD_transp_1
k141_5347_33	1121090.KB894709_gene1594	3.89e-106	313.0	COG1126@1|root,COG1126@2|Bacteria,1TNYD@1239|Firmicutes,4H9WY@91061|Bacilli,1ZB2E@1386|Bacillus	91061|Bacilli	E	COG1126 ABC-type polar amino acid transport system, ATPase component	-	-	3.6.3.21	ko:K02028	-	M00236	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.3	-	-	ABC_tran
k141_5347_34	1216932.CM240_0085	1.92e-31	120.0	COG0675@1|root,COG0675@2|Bacteria,1TRNY@1239|Firmicutes,247T1@186801|Clostridia,36E4A@31979|Clostridiaceae	186801|Clostridia	L	Transposase	-	-	-	ko:K07496	-	-	-	-	ko00000	-	-	-	HTH_OrfB_IS605,OrfB_IS605,OrfB_Zn_ribbon
k141_3356_1	1121396.KB893058_gene2570	8.98e-108	323.0	COG0609@1|root,COG0609@2|Bacteria,1MV9W@1224|Proteobacteria,42N5U@68525|delta/epsilon subdivisions,2WKV2@28221|Deltaproteobacteria,2MJK4@213118|Desulfobacterales	28221|Deltaproteobacteria	P	FecCD transport family	-	-	-	ko:K02015	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	FecCD
k141_3356_2	596152.DesU5LDRAFT_2629	1.85e-74	239.0	COG0614@1|root,COG0614@2|Bacteria,1NVK4@1224|Proteobacteria,42MBT@68525|delta/epsilon subdivisions,2WK1P@28221|Deltaproteobacteria,2MB0E@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	PFAM periplasmic binding protein	-	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
k141_3356_3	335541.Swol_1688	1.23e-62	200.0	COG0500@1|root,COG2226@2|Bacteria,1V7SG@1239|Firmicutes,24AEB@186801|Clostridia	186801|Clostridia	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
k141_5350_1	96561.Dole_1953	7.59e-36	136.0	COG1111@1|root,COG1205@1|root,COG1111@2|Bacteria,COG1205@2|Bacteria,1QU0I@1224|Proteobacteria,42M4R@68525|delta/epsilon subdivisions,2WK1V@28221|Deltaproteobacteria,2MI86@213118|Desulfobacterales	28221|Deltaproteobacteria	L	DEAD DEAH box helicase	yprA	-	-	ko:K06877	-	-	-	-	ko00000	-	-	-	DEAD,DUF1998,Helicase_C,RNase_H_2
k141_4399_1	1121459.AQXE01000002_gene1404	5.01e-20	94.7	COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,42M0Y@68525|delta/epsilon subdivisions,2WIR4@28221|Deltaproteobacteria,2M7T3@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	5TM-5TMR_LYT,GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg,dCache_1
k141_4399_2	439235.Dalk_3756	5.86e-195	564.0	COG1001@1|root,COG1001@2|Bacteria,1MVFP@1224|Proteobacteria,42NWX@68525|delta/epsilon subdivisions,2WIZY@28221|Deltaproteobacteria,2MJ6T@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family	ade	-	3.5.4.2	ko:K01486	ko00230,ko01100,map00230,map01100	-	R01244	RC00477	ko00000,ko00001,ko01000	-	-	-	Adenine_deam_C,Amidohydro_1
k141_3362_1	485916.Dtox_0939	4.37e-76	248.0	COG2274@1|root,COG2274@2|Bacteria,1V77J@1239|Firmicutes,25E7C@186801|Clostridia,261EJ@186807|Peptococcaceae	186801|Clostridia	V	NHLM bacteriocin system ABC transporter, peptidase ATP-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC_membrane,ABC_tran,Peptidase_C39
k141_3363_1	1168059.KB899087_gene2050	5.36e-37	134.0	COG4215@1|root,COG4215@2|Bacteria,1PGH0@1224|Proteobacteria,2V8BF@28211|Alphaproteobacteria,3F0AU@335928|Xanthobacteraceae	28211|Alphaproteobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02029	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	BPD_transp_1
k141_3363_2	331869.BAL199_16578	8.1e-05	44.3	COG0834@1|root,COG0834@2|Bacteria,1NT2J@1224|Proteobacteria,2VET9@28211|Alphaproteobacteria,4BQBI@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	ET	Ligated ion channel L-glutamate- and glycine-binding site	occT	-	-	ko:K10018	ko02010,map02010	M00231	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3.5,3.A.1.3.6	-	-	SBP_bac_3
k141_4400_1	443254.Marpi_0273	2.16e-43	154.0	28IA0@1|root,2Z8CM@2|Bacteria	2|Bacteria	S	Crispr-associated cxxc_cxxc protein Cst1	-	-	-	ko:K19088	-	-	-	-	ko00000,ko02048	-	-	-	Cas_CXXC_CXXC
k141_4400_2	443254.Marpi_0274	1.37e-179	508.0	COG1857@1|root,COG1857@2|Bacteria,2GDND@200918|Thermotogae	200918|Thermotogae	L	TIGRFAM CRISPR-associated autoregulator DevR family	-	-	-	ko:K19075	-	-	-	-	ko00000,ko02048	-	-	-	DevR
k141_2775_4	357808.RoseRS_3595	1.71e-23	95.1	COG0818@1|root,COG0818@2|Bacteria,2G75I@200795|Chloroflexi,375VY@32061|Chloroflexia	32061|Chloroflexia	M	PFAM diacylglycerol kinase	-	-	2.7.1.107	ko:K00901	ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00561,map00564,map01100,map01110,map04070,map04072,map05231	-	R02240	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	DAGK_prokar
k141_2107_1	1167006.UWK_00308	9.33e-09	56.6	COG0784@1|root,COG4191@1|root,COG5002@1|root,COG0784@2|Bacteria,COG4191@2|Bacteria,COG5002@2|Bacteria,1RCM9@1224|Proteobacteria,42N46@68525|delta/epsilon subdivisions,2WJT4@28221|Deltaproteobacteria,2MPMZ@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_4,Response_reg
k141_2107_2	945550.VISI1226_20964	4.02e-29	110.0	2E51T@1|root,30TP9@2|Bacteria,1QXDV@1224|Proteobacteria,1T39F@1236|Gammaproteobacteria,1XY6F@135623|Vibrionales	135623|Vibrionales	S	Protein of unknown function (DUF3305)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3305
k141_2107_3	29495.EA26_07975	2.25e-253	699.0	COG0004@1|root,COG0004@2|Bacteria,1NR9F@1224|Proteobacteria,1RMKD@1236|Gammaproteobacteria,1XSE7@135623|Vibrionales	135623|Vibrionales	P	ammonium transporter	-	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
k141_2107_4	55601.VANGNB10_cI1289c	1.66e-132	380.0	COG0846@1|root,COG0846@2|Bacteria,1MUK1@1224|Proteobacteria,1RMX5@1236|Gammaproteobacteria,1XSHS@135623|Vibrionales	135623|Vibrionales	K	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form	cobB	-	-	ko:K12410	-	-	-	-	ko00000,ko01000	-	-	-	SIR2
k141_2107_5	55601.VANGNB10_cI1288	5.02e-217	602.0	COG0687@1|root,COG0687@2|Bacteria,1MUYW@1224|Proteobacteria,1RM7W@1236|Gammaproteobacteria,1XUH1@135623|Vibrionales	135623|Vibrionales	P	Required for the activity of the bacterial periplasmic transport system of putrescine	potD	-	-	ko:K11069	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	SBP_bac_6,SBP_bac_8
k141_2108_1	985762.SAGN_02557	1.05e-54	189.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4H9ZY@91061|Bacilli,4GXQ4@90964|Staphylococcaceae	91061|Bacilli	V	ABC transporter transmembrane region	lmrA2	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
k141_1112_1	1121405.dsmv_2324	1.48e-141	431.0	COG4796@1|root,COG4796@2|Bacteria,1QTT6@1224|Proteobacteria,42MKN@68525|delta/epsilon subdivisions,2WJV6@28221|Deltaproteobacteria,2MHUC@213118|Desulfobacterales	28221|Deltaproteobacteria	U	type II and III secretion system protein	pilQ	-	-	ko:K02666	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	AMIN,STN,Secretin,Secretin_N
k141_2111_1	177439.DP1397	2.53e-77	244.0	COG1114@1|root,COG1114@2|Bacteria,1MVIF@1224|Proteobacteria,42M3P@68525|delta/epsilon subdivisions,2WQZ6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Component of the transport system for branched-chain amino acids	-	-	-	ko:K03311	-	-	-	-	ko00000	2.A.26	-	-	Branch_AA_trans
k141_3825_1	1175629.AJTG01000019_gene1628	9.19e-44	157.0	COG1109@1|root,COG1109@2|Bacteria,1TP1X@1239|Firmicutes,4HB16@91061|Bacilli,27DKP@186827|Aerococcaceae	91061|Bacilli	G	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate	glmM	-	5.4.2.10	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	-	R02060	RC00408	ko00000,ko00001,ko01000	-	-	iSB619.SA_RS11275	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
k141_3825_2	875454.BAEW01000001_gene27	3.25e-33	129.0	COG1109@1|root,COG1109@2|Bacteria,1TP1X@1239|Firmicutes,2499P@186801|Clostridia,22G7D@1570339|Peptoniphilaceae	186801|Clostridia	G	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate	glmM	-	5.4.2.10	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	-	R02060	RC00408	ko00000,ko00001,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
k141_3825_3	1304885.AUEY01000010_gene1697	3.72e-101	314.0	COG1207@1|root,COG1207@2|Bacteria,1R7DE@1224|Proteobacteria,42N1D@68525|delta/epsilon subdivisions,2WIRZ@28221|Deltaproteobacteria,2MHM4@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain	-	-	2.7.7.23,2.7.7.83	ko:K00972	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00361,M00362	R00416	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	-
k141_2112_1	1304885.AUEY01000089_gene130	2.02e-144	425.0	COG2067@1|root,COG2067@2|Bacteria,1MUU4@1224|Proteobacteria,42N9J@68525|delta/epsilon subdivisions,2WKR7@28221|Deltaproteobacteria,2MITN@213118|Desulfobacterales	28221|Deltaproteobacteria	I	PFAM membrane protein involved in aromatic hydrocarbon degradation	-	-	-	ko:K06076	-	-	-	-	ko00000,ko02000	1.B.9	-	-	Toluene_X
k141_4862_1	575788.VS_3019	2.97e-33	123.0	COG2177@1|root,COG2177@2|Bacteria,1MU65@1224|Proteobacteria,1RYBV@1236|Gammaproteobacteria,1XUCE@135623|Vibrionales	135623|Vibrionales	D	Part of the ABC transporter FtsEX involved in cellular division	ftsX	-	-	ko:K09811	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	FtsX
k141_5151_8	1304284.L21TH_0006	8.09e-37	142.0	COG0457@1|root,COG0457@2|Bacteria,1UJ4B@1239|Firmicutes,25EVP@186801|Clostridia,36JRU@31979|Clostridiaceae	186801|Clostridia	S	Copper amine oxidase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Cu_amine_oxidN1
k141_5151_9	931276.Cspa_c21800	2.51e-51	166.0	2E89A@1|root,332N5@2|Bacteria,1VEKY@1239|Firmicutes,25HQB@186801|Clostridia,36VBW@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_5151_11	1443125.Z962_06695	9.54e-175	494.0	COG1619@1|root,COG1619@2|Bacteria,1TRBB@1239|Firmicutes,24ABA@186801|Clostridia,36EBC@31979|Clostridiaceae	186801|Clostridia	V	PFAM peptidase U61, LD-carboxypeptidase A	mccF	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S66
k141_5151_12	1262449.CP6013_2783	1.6e-66	222.0	COG1413@1|root,COG1413@2|Bacteria,1V0R4@1239|Firmicutes,24IWZ@186801|Clostridia	186801|Clostridia	C	lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_5151_13	1051501.AYTL01000028_gene1709	1.75e-23	94.4	COG1733@1|root,COG1733@2|Bacteria,1VA9M@1239|Firmicutes,4HH0A@91061|Bacilli,1ZHCV@1386|Bacillus	91061|Bacilli	K	Transcriptional regulator	yybR	-	-	-	-	-	-	-	-	-	-	-	HxlR
k141_5151_14	641107.CDLVIII_4284	3.85e-89	266.0	COG1853@1|root,COG1853@2|Bacteria,1TSTQ@1239|Firmicutes,24FYK@186801|Clostridia,36EHC@31979|Clostridiaceae	186801|Clostridia	S	Flavin reductase like domain	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
k141_5151_15	626369.HMPREF0446_00709	6e-39	141.0	COG1011@1|root,COG1011@2|Bacteria,1TWM7@1239|Firmicutes,4HEXU@91061|Bacilli,27HEI@186828|Carnobacteriaceae	91061|Bacilli	S	HAD-hyrolase-like	yfnB	-	3.8.1.2	ko:K01560,ko:K07025	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05287	RC00697	ko00000,ko00001,ko01000	-	-	-	HAD_2
k141_5151_16	1158612.I580_02970	1.54e-54	180.0	COG2364@1|root,COG2364@2|Bacteria,1U63V@1239|Firmicutes,4HJ91@91061|Bacilli,4B184@81852|Enterococcaceae	91061|Bacilli	S	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_5151_17	457396.CSBG_00183	1.18e-34	124.0	COG1051@1|root,COG1051@2|Bacteria,1UK8J@1239|Firmicutes,25FQJ@186801|Clostridia,36V0F@31979|Clostridiaceae	186801|Clostridia	F	NUDIX domain	-	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
k141_5151_18	198467.NP92_00935	1.27e-74	232.0	COG0300@1|root,COG0300@2|Bacteria,1U5VD@1239|Firmicutes,4HES8@91061|Bacilli,21VC8@150247|Anoxybacillus	91061|Bacilli	S	Enoyl-(Acyl carrier protein) reductase	-	-	-	ko:K07124	-	-	-	-	ko00000	-	-	-	adh_short
k141_5151_20	931276.Cspa_c40570	5.01e-151	432.0	COG3586@1|root,COG3586@2|Bacteria,1U3JM@1239|Firmicutes,24BQ9@186801|Clostridia	186801|Clostridia	L	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures	-	-	-	-	-	-	-	-	-	-	-	-	NucS
k141_5151_21	546269.HMPREF0389_01439	2.12e-110	337.0	COG3593@1|root,COG3593@2|Bacteria,1VFE2@1239|Firmicutes,25G9C@186801|Clostridia	186801|Clostridia	L	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_15
k141_5151_22	546269.HMPREF0389_01440	1.89e-43	149.0	2DJAI@1|root,30597@2|Bacteria,1VP8U@1239|Firmicutes,24XDN@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_5151_23	574376.BAMA_23000	1.1e-48	167.0	COG1451@1|root,COG1451@2|Bacteria,1V0CS@1239|Firmicutes,4HE0S@91061|Bacilli,1ZBQ8@1386|Bacillus	91061|Bacilli	S	WLM domain	-	-	-	ko:K07043	-	-	-	-	ko00000	-	-	-	DUF45
k141_5151_24	1291050.JAGE01000002_gene3828	7.27e-32	112.0	COG4443@1|root,COG4443@2|Bacteria,1VEFE@1239|Firmicutes,24QV3@186801|Clostridia,3WJWY@541000|Ruminococcaceae	186801|Clostridia	S	Transcriptional Coactivator p15 (PC4)	-	-	-	-	-	-	-	-	-	-	-	-	PC4
k141_5151_28	1234679.BN424_2281	3.22e-110	338.0	COG0534@1|root,COG0534@2|Bacteria,1V3MS@1239|Firmicutes,4HI19@91061|Bacilli	91061|Bacilli	V	MatE	-	-	-	ko:K18908	-	M00705	-	-	ko00000,ko00002,ko01504,ko02000	2.A.66.1.13	-	-	MatE
k141_5151_29	350688.Clos_1703	2.01e-56	182.0	COG1670@1|root,COG1670@2|Bacteria,1UI20@1239|Firmicutes,24HRV@186801|Clostridia,36JDG@31979|Clostridiaceae	186801|Clostridia	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_4
k141_5151_31	1410653.JHVC01000003_gene3820	1.79e-87	274.0	COG0598@1|root,COG0598@2|Bacteria,1TPSV@1239|Firmicutes,24DE3@186801|Clostridia,36E87@31979|Clostridiaceae	186801|Clostridia	P	transport protein CorA	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
k141_5151_32	1165096.ARWF01000001_gene915	7.91e-43	167.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF,MASE1,PAS,PAS_3,PAS_4,PAS_9
k141_5151_34	1347392.CCEZ01000004_gene783	8.01e-32	117.0	COG1342@1|root,COG1342@2|Bacteria,1V7UV@1239|Firmicutes,24D5E@186801|Clostridia,36M1V@31979|Clostridiaceae	186801|Clostridia	S	Protein of unknown function  DUF134	-	-	-	-	-	-	-	-	-	-	-	-	DUF134
k141_5151_36	36875.HQ29_03930	3.47e-06	58.5	COG0793@1|root,COG0793@2|Bacteria,4PJ38@976|Bacteroidetes,2G1RE@200643|Bacteroidia,2313Z@171551|Porphyromonadaceae	976|Bacteroidetes	M	Peptidase family S41	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S41
k141_5151_38	1121324.CLIT_10c05490	8.11e-241	669.0	COG1653@1|root,COG1653@2|Bacteria,1TT8P@1239|Firmicutes,24DVQ@186801|Clostridia,25U8K@186804|Peptostreptococcaceae	186801|Clostridia	G	Bacterial extracellular solute-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_1,SBP_bac_8
k141_5151_39	272563.CD630_25490	1.39e-91	281.0	COG1175@1|root,COG1175@2|Bacteria,1TREE@1239|Firmicutes,24FFB@186801|Clostridia,25UI6@186804|Peptostreptococcaceae	186801|Clostridia	U	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02025	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
k141_5151_40	1121324.CLIT_10c05510	5.02e-123	358.0	COG0395@1|root,COG0395@2|Bacteria,1TR01@1239|Firmicutes,249Z7@186801|Clostridia	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
k141_5151_41	1292035.H476_2567	8.62e-71	246.0	COG3934@1|root,COG4552@1|root,COG3934@2|Bacteria,COG4552@2|Bacteria,1TRIX@1239|Firmicutes,25EXH@186801|Clostridia,25S7I@186804|Peptostreptococcaceae	186801|Clostridia	G	Domain of unknown function (DUF4091)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4091
k141_5151_42	1151292.QEW_3091	1.6e-177	521.0	COG3934@1|root,COG3934@2|Bacteria,1TRIX@1239|Firmicutes,25EXH@186801|Clostridia,25S7I@186804|Peptostreptococcaceae	186801|Clostridia	G	Domain of unknown function (DUF4091)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4091
k141_5151_43	754027.HMPREF9554_01513	2.43e-169	486.0	COG1301@1|root,COG1301@2|Bacteria,2J63V@203691|Spirochaetes	203691|Spirochaetes	U	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family	-	-	-	-	-	-	-	-	-	-	-	-	SDF
k141_5151_46	1220589.CD32_17485	1.27e-27	110.0	COG2184@1|root,COG2184@2|Bacteria,1TPUZ@1239|Firmicutes,4HIQT@91061|Bacilli	91061|Bacilli	D	Fic/DOC family	fic	-	-	ko:K04095	-	-	-	-	ko00000,ko03036	-	-	-	Fic
k141_5151_47	1301100.HG529403_gene6774	1.05e-126	365.0	COG0217@1|root,COG0217@2|Bacteria,1TPP5@1239|Firmicutes,247NK@186801|Clostridia,36E08@31979|Clostridiaceae	186801|Clostridia	K	transcriptional regulatory protein	yebC	-	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
k141_5151_48	767817.Desgi_4573	7.46e-23	90.5	COG2161@1|root,COG2161@2|Bacteria,1VFIZ@1239|Firmicutes,24PQN@186801|Clostridia	186801|Clostridia	D	Antitoxin component of a toxin-antitoxin (TA) module	-	-	-	ko:K19159	-	-	-	-	ko00000,ko02048	-	-	-	PhdYeFM_antitox
k141_5151_49	1169161.KB897741_gene1902	7.03e-29	105.0	COG4115@1|root,COG4115@2|Bacteria,2IQAJ@201174|Actinobacteria	201174|Actinobacteria	S	addiction module toxin, Txe YoeB family	-	-	-	ko:K19158	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	YoeB_toxin
k141_5151_50	1286171.EAL2_c11720	4.37e-80	246.0	COG1811@1|root,COG1811@2|Bacteria,1UH19@1239|Firmicutes,24AZ3@186801|Clostridia,25WNA@186806|Eubacteriaceae	186801|Clostridia	S	Protein of unknown function (DUF554)	-	-	-	ko:K07150	-	-	-	-	ko00000	-	-	-	DUF554
k141_5151_51	1321778.HMPREF1982_02841	6.72e-145	433.0	COG2268@1|root,COG2268@2|Bacteria,1TQDT@1239|Firmicutes,247MK@186801|Clostridia,268G1@186813|unclassified Clostridiales	186801|Clostridia	S	prohibitin homologues	-	-	-	ko:K07192	ko04910,map04910	-	-	-	ko00000,ko00001,ko03036,ko04131,ko04147	-	-	-	Band_7,Flot
k141_5151_52	350688.Clos_1044	1.15e-26	107.0	COG1585@1|root,COG1585@2|Bacteria,1VD3E@1239|Firmicutes,24H38@186801|Clostridia,36IDP@31979|Clostridiaceae	186801|Clostridia	OU	Membrane protein implicated in regulation of membrane protease activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF1449,NfeD
k141_5151_54	411474.COPEUT_02789	1e-11	72.4	COG1180@1|root,COG1180@2|Bacteria,1TPK2@1239|Firmicutes,247NA@186801|Clostridia	186801|Clostridia	C	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine	pflA	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
k141_5151_55	1347393.HG726025_gene2773	8.29e-279	802.0	COG1882@1|root,COG1882@2|Bacteria,4NDWW@976|Bacteroidetes,2FMC2@200643|Bacteroidia,4APPS@815|Bacteroidaceae	976|Bacteroidetes	C	Pyruvate formate lyase-like	-	-	2.3.1.54	ko:K00656	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	-	R00212,R06987	RC00004,RC01181,RC02742,RC02833	ko00000,ko00001,ko01000	-	-	-	Gly_radical,PFL-like
k141_5151_57	526218.Sterm_0367	1.37e-73	228.0	COG1418@1|root,COG1418@2|Bacteria	2|Bacteria	S	mRNA catabolic process	yagB	-	-	ko:K06950	-	-	-	-	ko00000	-	-	-	HD
k141_5151_58	1226325.HMPREF1548_02115	8.89e-254	723.0	COG1479@1|root,COG1479@2|Bacteria,1TPAT@1239|Firmicutes,24CP3@186801|Clostridia,36H6W@31979|Clostridiaceae	186801|Clostridia	S	Protein of unknown function (DUF1524)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1524,DUF262,DUF4268
k141_5151_61	1121324.CLIT_2c03700	1.24e-128	382.0	COG0420@1|root,COG0420@2|Bacteria,1TQY6@1239|Firmicutes,248VE@186801|Clostridia,25R9Z@186804|Peptostreptococcaceae	186801|Clostridia	L	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity	sbcD	-	-	ko:K03547	-	-	-	-	ko00000,ko03400	-	-	-	Metallophos,SbcD_C
k141_5151_62	1294142.CINTURNW_4086	4.21e-59	230.0	COG0419@1|root,COG0419@2|Bacteria,1TPCS@1239|Firmicutes,24A22@186801|Clostridia,36EN6@31979|Clostridiaceae	186801|Clostridia	L	exonuclease	sbcC	-	-	ko:K03546	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,AAA_29,SbcCD_C
k141_5151_63	1347392.CCEZ01000021_gene849	8.9e-35	119.0	COG1278@1|root,COG1278@2|Bacteria,1VEE0@1239|Firmicutes,24QJE@186801|Clostridia,36MMP@31979|Clostridiaceae	186801|Clostridia	K	Cold shock protein	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
k141_5151_64	1410653.JHVC01000032_gene1037	2.12e-83	266.0	COG5492@1|root,COG5492@2|Bacteria,1W2KG@1239|Firmicutes,24FQ5@186801|Clostridia,36E2B@31979|Clostridiaceae	186801|Clostridia	N	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_5151_65	195103.CPF_0327	6.29e-281	795.0	COG0514@1|root,COG0514@2|Bacteria,1TPN5@1239|Firmicutes,247ZA@186801|Clostridia,36DC9@31979|Clostridiaceae	186801|Clostridia	L	ATP-dependent DNA helicase RecQ	recQ	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,HRDC,HTH_40,Helicase_C,RQC,RecQ_Zn_bind
k141_5151_66	1408439.JHXW01000001_gene1882	3.86e-05	51.6	COG0454@1|root,COG0456@2|Bacteria,37AQU@32066|Fusobacteria	32066|Fusobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_7
k141_5151_68	1121324.CLIT_10c04250	8.17e-153	442.0	COG0842@1|root,COG0842@2|Bacteria,1TQG7@1239|Firmicutes,249TT@186801|Clostridia	186801|Clostridia	V	PFAM ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
k141_5151_69	1121324.CLIT_10c04240	6.52e-103	307.0	COG1131@1|root,COG1131@2|Bacteria,1TQKM@1239|Firmicutes,25B35@186801|Clostridia	186801|Clostridia	V	PFAM ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
k141_5151_70	1121324.CLIT_10c04230	3.99e-77	246.0	COG1566@1|root,COG1566@2|Bacteria,1UJ4C@1239|Firmicutes,25EVQ@186801|Clostridia	186801|Clostridia	V	Barrel-sandwich domain of CusB or HlyD membrane-fusion	-	-	-	ko:K01993	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23,OEP
k141_5151_71	1121324.CLIT_2c03720	1.68e-105	310.0	COG1272@1|root,COG1272@2|Bacteria,1TSFK@1239|Firmicutes,24CPT@186801|Clostridia	186801|Clostridia	S	channel protein, hemolysin III family	-	-	-	ko:K11068	-	-	-	-	ko00000,ko02042	-	-	-	HlyIII
k141_5151_72	1033737.CAEV01000025_gene372	7.25e-60	199.0	COG1284@1|root,COG1284@2|Bacteria,1TRAU@1239|Firmicutes,249DE@186801|Clostridia,36EK0@31979|Clostridiaceae	186801|Clostridia	S	hmm pf02588	-	-	-	-	-	-	-	-	-	-	-	-	DUF2179,YitT_membrane
k141_5151_73	1565129.JSFF01000033_gene1462	8.23e-36	151.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,2Q8RK@267890|Shewanellaceae	1236|Gammaproteobacteria	NT	PFAM histidine kinase, HAMP region domain protein	-	-	-	ko:K03406,ko:K10937	ko02020,ko02030,ko05111,map02020,map02030,map05111	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal
k141_5151_74	536232.CLM_1456	7.58e-86	285.0	COG5298@1|root,COG5298@2|Bacteria,1TSDC@1239|Firmicutes,25E03@186801|Clostridia,36FPX@31979|Clostridiaceae	186801|Clostridia	S	Uncharacterized protein conserved in bacteria (DUF2334)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2334
k141_5151_75	1122917.KB899663_gene2739	5.74e-148	449.0	COG5448@1|root,COG5448@2|Bacteria,1VUWS@1239|Firmicutes,4HVU6@91061|Bacilli	91061|Bacilli	S	Glycoside hydrolase family 24	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_5151_76	1033737.CAEV01000092_gene1949	5.44e-71	218.0	COG3542@1|root,COG3542@2|Bacteria,1V52Y@1239|Firmicutes,24GKZ@186801|Clostridia,36I2M@31979|Clostridiaceae	186801|Clostridia	S	Cupin superfamily (DUF985)	-	-	-	ko:K09705	-	-	-	-	ko00000	-	-	-	Cupin_5
k141_5151_77	37659.JNLN01000001_gene1280	1.03e-14	86.7	COG0840@1|root,COG0840@2|Bacteria,1TP5A@1239|Firmicutes,247S3@186801|Clostridia,36EVU@31979|Clostridiaceae	186801|Clostridia	NT	histidine kinase HAMP region domain protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal,dCache_1
k141_5151_78	1541959.KQ51_01293	2.35e-19	91.3	COG0664@1|root,COG0664@2|Bacteria	2|Bacteria	T	cyclic nucleotide binding	-	-	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
k141_5151_79	445335.CBN_3660	5.24e-87	268.0	COG1180@1|root,COG1180@2|Bacteria,1TPK2@1239|Firmicutes,24871@186801|Clostridia,36F0C@31979|Clostridiaceae	186801|Clostridia	O	radical SAM domain protein	yjjW	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4,Fer4_12,Fer4_6,Radical_SAM
k141_5151_80	857293.CAAU_0062	1.48e-224	634.0	COG1328@1|root,COG1328@2|Bacteria,1TPAC@1239|Firmicutes,24A2W@186801|Clostridia,36GU2@31979|Clostridiaceae	186801|Clostridia	F	Protein of unknown function (DUF3029)	yjjI	-	-	-	-	-	-	-	-	-	-	-	DUF3029
k141_5151_81	1410653.JHVC01000006_gene32	1.23e-34	144.0	COG0840@1|root,COG0840@2|Bacteria,1TP5A@1239|Firmicutes,247S3@186801|Clostridia,36J4H@31979|Clostridiaceae	186801|Clostridia	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal
k141_5151_82	1347086.CCBA010000007_gene4530	1.77e-66	217.0	COG0697@1|root,COG0697@2|Bacteria,1TYSF@1239|Firmicutes,4HE6Y@91061|Bacilli,1ZQ37@1386|Bacillus	91061|Bacilli	EG	EamA-like transporter family	ycxC	-	-	-	-	-	-	-	-	-	-	-	EamA
k141_5151_83	445335.CBN_1315	2.36e-74	228.0	COG1396@1|root,COG1917@1|root,COG1396@2|Bacteria,COG1917@2|Bacteria,1V1K5@1239|Firmicutes,24FTC@186801|Clostridia,36F4A@31979|Clostridiaceae	186801|Clostridia	K	Transcriptional regulator	puuR	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,HTH_19,HTH_3
k141_5151_84	1121335.Clst_1721	4.1e-10	72.8	COG0840@1|root,COG0840@2|Bacteria,1UZ0J@1239|Firmicutes,24F2H@186801|Clostridia	186801|Clostridia	NT	Chemotaxis	pilJ	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal
k141_5151_85	1487921.DP68_14360	7.75e-174	494.0	COG0006@1|root,COG0006@2|Bacteria,1TQ6R@1239|Firmicutes,25CCC@186801|Clostridia,36WTC@31979|Clostridiaceae	186801|Clostridia	E	Creatinase/Prolidase N-terminal domain	pepQ	-	3.4.13.9	ko:K01271	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Creatinase_N,Peptidase_M24
k141_5151_86	1243664.CAVL020000032_gene2872	4.72e-53	174.0	COG1396@1|root,COG1917@1|root,COG1396@2|Bacteria,COG1917@2|Bacteria,1V88H@1239|Firmicutes,4HMXE@91061|Bacilli,1ZCZV@1386|Bacillus	91061|Bacilli	K	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,HTH_19,HTH_3
k141_5151_87	935845.JADQ01000047_gene2486	1.7e-114	346.0	COG4214@1|root,COG4214@2|Bacteria,1VU1F@1239|Firmicutes,4HBDM@91061|Bacilli,26T54@186822|Paenibacillaceae	91061|Bacilli	G	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K10544	ko02010,map02010	M00215	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.4	-	-	BPD_transp_2
k141_319_1	1233951.IO90_05090	3.49e-63	207.0	COG2017@1|root,COG2017@2|Bacteria,4NMWB@976|Bacteroidetes,1HWV5@117743|Flavobacteriia,3HHPJ@358033|Chryseobacterium	976|Bacteroidetes	G	Aldose 1-epimerase	lacX	-	-	-	-	-	-	-	-	-	-	-	Aldose_epim
k141_319_2	237368.SCABRO_00809	1.9e-23	91.7	COG2336@1|root,COG2336@2|Bacteria	2|Bacteria	T	PFAM SpoVT AbrB	mazE	-	-	ko:K07172,ko:K18842	-	-	-	-	ko00000,ko02048	-	-	-	MazE_antitoxin
k141_4965_1	667014.Thein_2191	9.84e-41	143.0	COG0190@1|root,COG0190@2|Bacteria,2GH19@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	H	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	-	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
k141_4965_2	760568.Desku_3479	5.31e-82	266.0	COG0591@1|root,COG0591@2|Bacteria,1TPVE@1239|Firmicutes,248NQ@186801|Clostridia,260ZM@186807|Peptococcaceae	186801|Clostridia	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K03307,ko:K11928	-	-	-	-	ko00000,ko02000	2.A.21,2.A.21.2	-	-	SSF
k141_1274_1	298386.PBPRB1125	2.01e-48	169.0	COG4591@1|root,COG4591@2|Bacteria,1R4Q2@1224|Proteobacteria,1S7I9@1236|Gammaproteobacteria,1XU7J@135623|Vibrionales	135623|Vibrionales	M	MacB-like periplasmic core domain	VPA0559	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
k141_1274_2	223926.28808726	2.37e-119	346.0	COG1136@1|root,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,1S4GN@1236|Gammaproteobacteria,1Y2TK@135623|Vibrionales	135623|Vibrionales	V	abc transporter atp-binding protein	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
k141_1274_3	298386.PBPRB1123	1.83e-126	377.0	2C2F5@1|root,32WND@2|Bacteria,1R7B4@1224|Proteobacteria,1RZJV@1236|Gammaproteobacteria,1XTNW@135623|Vibrionales	135623|Vibrionales	-	-	VPA0561	-	-	-	-	-	-	-	-	-	-	-	-
k141_3644_1	706587.Desti_2922	2.71e-08	56.2	COG0501@1|root,COG0501@2|Bacteria,1MUNA@1224|Proteobacteria,43BJA@68525|delta/epsilon subdivisions,2WME6@28221|Deltaproteobacteria,2MS70@213462|Syntrophobacterales	28221|Deltaproteobacteria	O	Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
k141_1275_2	1303518.CCALI_02745	4.49e-13	71.6	COG2199@1|root,COG2203@1|root,COG3437@1|root,COG2203@2|Bacteria,COG3437@2|Bacteria,COG3706@2|Bacteria	2|Bacteria	T	GGDEF domain	-	-	-	ko:K07814	-	-	-	-	ko00000,ko02022	-	-	-	GAF,GAF_2,GGDEF,HATPase_c,HD,HD_5,HWE_HK,PAS,PAS_3,PAS_4,PAS_9,Response_reg
k141_593_1	203122.Sde_2049	6.58e-46	169.0	COG5184@1|root,COG5276@1|root,COG5644@1|root,COG5184@2|Bacteria,COG5276@2|Bacteria,COG5644@2|Bacteria,1QX03@1224|Proteobacteria,1T31Q@1236|Gammaproteobacteria	1236|Gammaproteobacteria	DZ	regulator of chromosome condensation, RCC1	-	-	-	-	-	-	-	-	-	-	-	-	RCC1_2
k141_4270_2	298386.PBPRA3496	8.02e-163	465.0	COG1816@1|root,COG1816@2|Bacteria,1MWBV@1224|Proteobacteria,1RNVI@1236|Gammaproteobacteria,1XU9B@135623|Vibrionales	135623|Vibrionales	F	COG1816 Adenosine deaminase	add	GO:0003674,GO:0003824,GO:0004000,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006144,GO:0006152,GO:0006154,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009113,GO:0009116,GO:0009119,GO:0009163,GO:0009164,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017144,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042278,GO:0042440,GO:0042451,GO:0042454,GO:0042455,GO:0042737,GO:0043094,GO:0043096,GO:0043101,GO:0043103,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046085,GO:0046100,GO:0046101,GO:0046102,GO:0046103,GO:0046112,GO:0046128,GO:0046129,GO:0046130,GO:0046148,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0072523,GO:1901135,GO:1901136,GO:1901137,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901657,GO:1901658,GO:1901659	3.5.4.4	ko:K01488	ko00230,ko01100,ko05340,map00230,map01100,map05340	-	R01560,R02556	RC00477	ko00000,ko00001,ko01000	-	-	-	A_deaminase
k141_4270_3	87626.PTD2_22687	3.25e-05	45.1	2DRSC@1|root,33CUR@2|Bacteria,1P8XC@1224|Proteobacteria,1SUAK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_2272_1	1191299.AJYX01000096_gene1944	1.91e-103	304.0	COG1280@1|root,COG1280@2|Bacteria,1R3YJ@1224|Proteobacteria,1RSMF@1236|Gammaproteobacteria,1XWJ7@135623|Vibrionales	135623|Vibrionales	E	LysE type translocator	-	-	-	-	-	-	-	-	-	-	-	-	LysE
k141_2272_2	411463.EUBVEN_01807	1.92e-11	71.6	COG2207@1|root,COG2207@2|Bacteria,1TR2K@1239|Firmicutes,24ABH@186801|Clostridia,25UUD@186806|Eubacteriaceae	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18,HTH_AraC
k141_2272_4	314275.MADE_1010640	1.49e-17	78.2	COG2259@1|root,COG2259@2|Bacteria,1RDYW@1224|Proteobacteria,1S3RT@1236|Gammaproteobacteria,466ZI@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	TQO small subunit DoxD	-	-	-	ko:K15977	-	-	-	-	ko00000	-	-	-	DoxX
k141_594_2	861530.ALOZ01000034_gene253	0.000593	44.3	COG1396@1|root,COG1396@2|Bacteria,1V1K5@1239|Firmicutes,4HHAY@91061|Bacilli,4GYKB@90964|Staphylococcaceae	91061|Bacilli	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,HTH_3
k141_4966_2	1280001.BAOA01000048_gene1840	1.27e-38	148.0	COG3164@1|root,COG3164@2|Bacteria,1MXWF@1224|Proteobacteria,1RNUK@1236|Gammaproteobacteria,1XTHT@135623|Vibrionales	135623|Vibrionales	S	Protein of unknown function	VV2929	-	-	-	-	-	-	-	-	-	-	-	AsmA_2,DUF3971
k141_3943_1	1304885.AUEY01000031_gene42	7.94e-203	580.0	COG0568@1|root,COG0568@2|Bacteria,1MVNJ@1224|Proteobacteria,42N2S@68525|delta/epsilon subdivisions,2WJ0E@28221|Deltaproteobacteria,2MHX2@213118|Desulfobacterales	28221|Deltaproteobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	rpoD	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_ner,Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
k141_3943_2	879212.DespoDRAFT_03262	8.43e-59	195.0	COG0327@1|root,COG0327@2|Bacteria,1MVUN@1224|Proteobacteria,42MHJ@68525|delta/epsilon subdivisions,2WM6S@28221|Deltaproteobacteria,2MJJ3@213118|Desulfobacterales	28221|Deltaproteobacteria	S	NGG1p interacting factor 3	-	-	3.5.4.16	ko:K22391	ko00790,ko01100,map00790,map01100	M00126	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	NIF3
k141_3943_3	760142.Hipma_1246	3.29e-09	63.5	COG1579@1|root,COG1579@2|Bacteria,1R7GT@1224|Proteobacteria,42P3S@68525|delta/epsilon subdivisions,2WSCV@28221|Deltaproteobacteria,2M6CB@213113|Desulfurellales	28221|Deltaproteobacteria	S	C4-type zinc ribbon domain	-	-	-	ko:K07164	-	-	-	-	ko00000	-	-	-	zf-RING_7
k141_3943_4	933262.AXAM01000002_gene512	6.3e-169	488.0	COG1925@1|root,COG1925@2|Bacteria,1PW7I@1224|Proteobacteria,42N77@68525|delta/epsilon subdivisions,2WKSU@28221|Deltaproteobacteria,2MI26@213118|Desulfobacterales	28221|Deltaproteobacteria	G	phosphoenolpyruvate-dependent sugar phosphotransferase system	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_3943_5	1450694.BTS2_1883	3.65e-11	64.3	COG1211@1|root,COG1211@2|Bacteria,1V3M7@1239|Firmicutes,4HFH7@91061|Bacilli,1ZE75@1386|Bacillus	91061|Bacilli	I	Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate	tarI	GO:0003674,GO:0003824,GO:0016740,GO:0016772,GO:0016779,GO:0050518,GO:0070567	2.7.7.40,2.7.7.60	ko:K00991,ko:K21030	ko00040,ko00900,ko01100,ko01110,ko01130,map00040,map00900,map01100,map01110,map01130	M00096	R02921,R05633	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD
k141_2845_2	55601.VANGNB10_cII0854c	3.48e-98	292.0	COG3039@1|root,COG3039@2|Bacteria,1MXTN@1224|Proteobacteria,1RM94@1236|Gammaproteobacteria,1XVGA@135623|Vibrionales	135623|Vibrionales	L	User locus_tag	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_5
k141_1276_1	338963.Pcar_0530	1.29e-46	158.0	COG0500@1|root,COG2226@2|Bacteria,1Q0P4@1224|Proteobacteria,42T38@68525|delta/epsilon subdivisions,2WPX9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	Q	PFAM Methyltransferase type	-	-	-	ko:K15256	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_25
k141_1948_1	553973.CLOHYLEM_05415	0.0	1020.0	COG1882@1|root,COG1882@2|Bacteria,1TPTF@1239|Firmicutes,247YY@186801|Clostridia,21Y97@1506553|Lachnoclostridium	186801|Clostridia	C	Psort location Cytoplasmic, score 9.98	-	-	4.3.99.4	ko:K20038	-	-	-	-	ko00000,ko01000	-	-	-	Gly_radical,PFL-like
k141_1948_2	1286171.EAL2_808p07040	2.24e-72	232.0	COG1180@1|root,COG1180@2|Bacteria,1TPK2@1239|Firmicutes,24871@186801|Clostridia,25W5G@186806|Eubacteriaceae	186801|Clostridia	C	glycyl-radical enzyme activating protein family	pflC	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4,Fer4_12,Radical_SAM
k141_1948_4	945543.VIBR0546_03390	7.99e-53	173.0	COG1396@1|root,COG1917@1|root,COG1396@2|Bacteria,COG1917@2|Bacteria,1R4NU@1224|Proteobacteria,1RQG0@1236|Gammaproteobacteria,1XUWN@135623|Vibrionales	135623|Vibrionales	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,HTH_3
k141_1948_5	1283284.AZUK01000001_gene505	3.83e-57	189.0	COG1820@1|root,COG1820@2|Bacteria,1MW8Y@1224|Proteobacteria,1RMRV@1236|Gammaproteobacteria,1Y3SZ@135624|Aeromonadales	135624|Aeromonadales	G	Belongs to the metallo-dependent hydrolases superfamily. NagA family	nagA	-	3.5.1.25	ko:K01443	ko00520,ko01130,map00520,map01130	-	R02059	RC00166,RC00300	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
k141_595_1	1304885.AUEY01000079_gene1030	8.11e-42	158.0	COG0304@1|root,COG1028@1|root,COG2070@1|root,COG3321@1|root,COG0304@2|Bacteria,COG1028@2|Bacteria,COG2070@2|Bacteria,COG3321@2|Bacteria,1R89Z@1224|Proteobacteria,42NGA@68525|delta/epsilon subdivisions,2WJK3@28221|Deltaproteobacteria,2MIK4@213118|Desulfobacterales	28221|Deltaproteobacteria	IQ	Beta-ketoacyl synthase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_1,KAsynt_C_assoc,KR,Ketoacyl-synt_C,NMO,PP-binding,PS-DH,ketoacyl-synt
k141_3241_1	29495.EA26_15020	1.59e-122	365.0	COG4974@1|root,COG4974@2|Bacteria,1NY1A@1224|Proteobacteria,1RN33@1236|Gammaproteobacteria,1XTA8@135623|Vibrionales	135623|Vibrionales	L	Transposase ISVa5 (IS66-family	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS66,DDE_Tnp_IS66_C,LZ_Tnp_IS66,zf-IS66
k141_3241_2	298386.PBPRA1824	1.19e-66	203.0	COG3436@1|root,COG3436@2|Bacteria,1MZFT@1224|Proteobacteria,1SABV@1236|Gammaproteobacteria,1Y27X@135623|Vibrionales	135623|Vibrionales	L	transposase, ISVa5 (IS66-family	-	-	-	-	-	-	-	-	-	-	-	-	TnpB_IS66
k141_3241_4	675813.VIB_002642	4.72e-79	243.0	COG0604@1|root,COG0604@2|Bacteria,1MXCV@1224|Proteobacteria,1S0AH@1236|Gammaproteobacteria,1XVK0@135623|Vibrionales	135623|Vibrionales	C	Alcohol dehydrogenase GroES-like domain	-	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N_2
k141_596_1	1333998.M2A_0433	7.69e-16	85.1	COG3250@1|root,COG3250@2|Bacteria,1R87I@1224|Proteobacteria	1224|Proteobacteria	G	Protein of unknown function (DUF2804)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2804
k141_1277_1	345073.VC395_A0962	1.86e-143	410.0	COG2207@1|root,COG2207@2|Bacteria,1NETZ@1224|Proteobacteria,1RRXN@1236|Gammaproteobacteria,1XSYH@135623|Vibrionales	135623|Vibrionales	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
k141_1277_2	1454202.PPBDW_130860___1	1.58e-24	100.0	COG0418@1|root,COG0418@2|Bacteria,1MUYP@1224|Proteobacteria,1RNEN@1236|Gammaproteobacteria,1XSNV@135623|Vibrionales	135623|Vibrionales	F	Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate	pyrC	GO:0003674,GO:0003824,GO:0004151,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
k141_5233_3	675814.VIC_000580	5.19e-170	479.0	COG0681@1|root,COG0681@2|Bacteria,1MXUF@1224|Proteobacteria,1RMHI@1236|Gammaproteobacteria,1XUWQ@135623|Vibrionales	135623|Vibrionales	U	Belongs to the peptidase S26 family	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
k141_5233_5	617140.AJZE01000084_gene2724	5.44e-52	169.0	COG3086@1|root,COG3086@2|Bacteria,1N6QS@1224|Proteobacteria,1SCTM@1236|Gammaproteobacteria,1XWZF@135623|Vibrionales	135623|Vibrionales	T	COG3086 Positive regulator of sigma E activity	rseC	-	-	ko:K03803	-	-	-	-	ko00000,ko03021	-	-	-	RseC_MucC
k141_5233_6	243277.VC_2465	4.55e-163	464.0	COG3026@1|root,COG3026@2|Bacteria,1MUQ8@1224|Proteobacteria,1RNF3@1236|Gammaproteobacteria,1XSY1@135623|Vibrionales	135623|Vibrionales	T	COG3026 Negative regulator of sigma E activity	rseB	-	-	ko:K03598	-	-	-	-	ko00000,ko03021	-	-	-	MucB_RseB,MucB_RseB_C
k141_5233_7	55601.VANGNB10_cI2226c	1.07e-39	137.0	COG3073@1|root,COG3073@2|Bacteria,1R4U0@1224|Proteobacteria,1RN98@1236|Gammaproteobacteria,1XSUI@135623|Vibrionales	135623|Vibrionales	T	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E	rseA	-	-	ko:K03597	-	-	-	-	ko00000,ko03021	-	-	-	RseA_C,RseA_N
k141_4273_1	1121342.AUCO01000009_gene363	1.26e-53	179.0	COG1994@1|root,COG1994@2|Bacteria,1TSA9@1239|Firmicutes,24CR6@186801|Clostridia,36GS8@31979|Clostridiaceae	186801|Clostridia	S	Peptidase family M50	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_597_1	1304885.AUEY01000049_gene1225	2.56e-26	107.0	COG2236@1|root,COG4121@1|root,COG2236@2|Bacteria,COG4121@2|Bacteria,1PNQ7@1224|Proteobacteria,43A2N@68525|delta/epsilon subdivisions,2X9D9@28221|Deltaproteobacteria,2MP4Y@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Phosphoribosyl transferase domain	-	-	-	ko:K07101	-	-	-	-	ko00000	-	-	-	Pribosyltran
k141_597_2	1319815.HMPREF0202_02294	1.25e-67	219.0	COG2252@1|root,COG2252@2|Bacteria,37914@32066|Fusobacteria	32066|Fusobacteria	S	Psort location CytoplasmicMembrane, score 10.00	-	-	-	ko:K06901	-	-	-	-	ko00000,ko02000	2.A.1.40	-	-	Xan_ur_permease
k141_3645_1	1517681.HW45_09460	5.08e-157	454.0	COG1455@1|root,COG1455@2|Bacteria,1PVNT@1224|Proteobacteria,1RR0W@1236|Gammaproteobacteria,1Y0BD@135623|Vibrionales	135623|Vibrionales	G	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane	-	-	-	ko:K02761	ko00500,ko02060,map00500,map02060	M00275	R11170,R11172	RC00017,RC03206	ko00000,ko00001,ko00002,ko02000	4.A.3.2	-	-	PTS_EIIC
k141_3242_3	509191.AEDB02000073_gene1885	3.08e-98	298.0	COG0384@1|root,COG0384@2|Bacteria,1TRAF@1239|Firmicutes,25D2F@186801|Clostridia,3WSFK@541000|Ruminococcaceae	186801|Clostridia	S	Phenazine biosynthesis-like protein	-	-	-	-	-	-	-	-	-	-	-	-	PhzC-PhzF
k141_864_1	906968.Trebr_0610	2.12e-42	168.0	COG1283@1|root,COG1283@2|Bacteria,2J64N@203691|Spirochaetes	203691|Spirochaetes	P	Na Pi-cotransporter	-	-	-	ko:K03324	-	-	-	-	ko00000,ko02000	2.A.58.2	-	-	Na_Pi_cotrans,PhoU
k141_864_3	933262.AXAM01000060_gene2892	2.09e-12	67.8	COG4191@1|root,COG4191@2|Bacteria,1MY5P@1224|Proteobacteria,42MTA@68525|delta/epsilon subdivisions,2WJ9Q@28221|Deltaproteobacteria,2MIRX@213118|Desulfobacterales	28221|Deltaproteobacteria	T	PFAM ATP-binding region ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	4HB_MCP_1,CHASE3,HAMP,HATPase_c,HisKA
k141_4667_1	177437.HRM2_06660	6.6e-42	155.0	COG1847@1|root,COG1847@2|Bacteria,1RB1P@1224|Proteobacteria,42QPK@68525|delta/epsilon subdivisions,2WN58@28221|Deltaproteobacteria,2MJJC@213118|Desulfobacterales	28221|Deltaproteobacteria	S	PFAM single-stranded nucleic acid binding R3H	-	-	-	ko:K06346	-	-	-	-	ko00000	-	-	-	Jag_N,KH_4,R3H
k141_4667_2	431943.CKL_3921	1.28e-92	290.0	COG0486@1|root,COG0486@2|Bacteria,1TPJF@1239|Firmicutes,248A9@186801|Clostridia,36ECR@31979|Clostridiaceae	186801|Clostridia	J	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34	mnmE	-	-	ko:K03650	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko01000,ko03016	-	-	-	MMR_HSR1,MnmE_helical,TrmE_N
k141_3957_1	1187848.AJYQ01000117_gene1313	4.84e-42	143.0	COG4969@1|root,COG4969@2|Bacteria,1N7EQ@1224|Proteobacteria,1SCES@1236|Gammaproteobacteria,1XYET@135623|Vibrionales	135623|Vibrionales	NU	Belongs to the N-Me-Phe pilin family	pilA	-	-	ko:K02650	ko02020,map02020	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.15.2	-	-	N_methyl,Pilin
k141_3957_2	1248232.BANQ01000088_gene2600	3.33e-148	444.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,1RMBS@1236|Gammaproteobacteria,1XUSD@135623|Vibrionales	135623|Vibrionales	NU	COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB	pilB	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE,T2SSE_N
k141_3957_3	1336237.JAEE01000001_gene1909	2.56e-18	89.7	COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,1RNV0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	U	type II secretion system	hofC	GO:0002790,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015628,GO:0015833,GO:0016020,GO:0032940,GO:0033036,GO:0042886,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098776	-	ko:K02505,ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
k141_865_1	485915.Dret_0850	2.16e-172	488.0	COG1494@1|root,COG1494@2|Bacteria,1MUB1@1224|Proteobacteria,42M34@68525|delta/epsilon subdivisions,2WKJ6@28221|Deltaproteobacteria,2M9D4@213115|Desulfovibrionales	28221|Deltaproteobacteria	G	TIGRFAM fructose-1,6-bisphosphatase, class II	glpX	-	3.1.3.11	ko:K02446	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00165,M00167	R00762,R04780	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FBPase_glpX
k141_3254_2	555779.Dthio_PD3706	4.27e-51	164.0	COG3436@1|root,COG3436@2|Bacteria,1N638@1224|Proteobacteria,430NK@68525|delta/epsilon subdivisions,2WVZ0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	PFAM IS66 Orf2 family protein	-	-	-	ko:K07484	-	-	-	-	ko00000	-	-	-	TnpB_IS66
k141_3254_3	555779.Dthio_PD3704	7.62e-86	274.0	COG4974@1|root,COG4974@2|Bacteria,1RC0C@1224|Proteobacteria,42W1W@68525|delta/epsilon subdivisions,2WRTZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	PFAM transposase IS66	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS66
k141_1970_1	205914.HS_1374	1.51e-20	86.7	2AUN7@1|root,31KB2@2|Bacteria,1QI5G@1224|Proteobacteria,1TFZ5@1236|Gammaproteobacteria,1YAHK@135625|Pasteurellales	135625|Pasteurellales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_1970_2	675816.VIA_001502	2.71e-33	129.0	2DP21@1|root,3307B@2|Bacteria,1QTZG@1224|Proteobacteria,1T1PM@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	KilA-N	-	-	-	-	-	-	-	-	-	-	-	-	HTH_39,KilA-N
k141_1970_3	870967.VIS19158_14729	3.46e-83	248.0	COG0735@1|root,COG0735@2|Bacteria,1MZIW@1224|Proteobacteria,1S5ZI@1236|Gammaproteobacteria,1XWW0@135623|Vibrionales	135623|Vibrionales	K	Belongs to the Fur family	zur	-	-	ko:K09823	ko02024,map02024	-	-	-	ko00000,ko00001,ko03000	-	-	-	FUR
k141_2541_1	672.VV93_v1c20490	2.26e-148	422.0	COG4598@1|root,COG4598@2|Bacteria,1QTS2@1224|Proteobacteria,1RQYN@1236|Gammaproteobacteria,1XU3M@135623|Vibrionales	135623|Vibrionales	E	COG4598 ABC-type histidine transport system, ATPase component	aotP	-	-	ko:K10025	ko02010,map02010	M00235	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.3.11	-	-	ABC_tran
k141_2541_2	55601.VANGNB10_cI1689c	2.86e-154	436.0	COG0834@1|root,COG0834@2|Bacteria,1NT2J@1224|Proteobacteria,1S077@1236|Gammaproteobacteria,1XT44@135623|Vibrionales	135623|Vibrionales	ET	COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain	aotJ	-	-	ko:K10022	ko02010,map02010	M00235	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3.11	-	-	SBP_bac_3
k141_2541_3	1219080.VEZ01S_09_00730	2.9e-89	267.0	COG4215@1|root,COG4215@2|Bacteria,1MY2N@1224|Proteobacteria,1RNYD@1236|Gammaproteobacteria,1XT6H@135623|Vibrionales	135623|Vibrionales	P	COG4215 ABC-type arginine transport system, permease component	aotQ	-	-	ko:K10024	ko02010,map02010	M00235	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3.11	-	-	BPD_transp_1
k141_866_1	796620.VIBC2010_15279	1.62e-13	75.9	2AVXK@1|root,31MRN@2|Bacteria,1QJID@1224|Proteobacteria,1THIM@1236|Gammaproteobacteria,1XW51@135623|Vibrionales	135623|Vibrionales	S	N-acyl homoserine lactone synthase activity	luxM	-	2.3.1.184	ko:K13062	ko00270,ko01100,ko02024,map00270,map01100,map02024	-	R08940	RC00021,RC00039	ko00000,ko00001,ko01000	-	-	-	AHL_synthase
k141_4668_1	880072.Desac_0652	3.2e-87	264.0	COG1830@1|root,COG1830@2|Bacteria,1MWJW@1224|Proteobacteria,42NP9@68525|delta/epsilon subdivisions,2WIP9@28221|Deltaproteobacteria,2MRSW@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	DeoC/LacD family aldolase	aroA'	-	4.1.2.13	ko:K11645	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	DeoC
k141_4668_2	1304885.AUEY01000048_gene609	1.77e-149	430.0	COG1465@1|root,COG1465@2|Bacteria,1P42W@1224|Proteobacteria,42MQM@68525|delta/epsilon subdivisions,2WK5X@28221|Deltaproteobacteria,2MIRC@213118|Desulfobacterales	28221|Deltaproteobacteria	E	3-dehydroquinate synthase (EC 4.6.1.3)	-	-	1.4.1.24	ko:K11646	ko00400,ko01110,ko01130,map00400,map01110,map01130	-	R08569	RC02302	ko00000,ko00001,ko01000	-	-	-	DHQS
k141_4668_3	1121396.KB893099_gene4285	3.81e-09	58.2	COG0077@1|root,COG1605@1|root,COG0077@2|Bacteria,COG1605@2|Bacteria,1MU60@1224|Proteobacteria,42MGN@68525|delta/epsilon subdivisions,2WJET@28221|Deltaproteobacteria,2MIFU@213118|Desulfobacterales	28221|Deltaproteobacteria	E	PFAM Prephenate dehydratase	pheA	-	4.2.1.51,5.4.99.5	ko:K14170	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R00691,R01373,R01715	RC00360,RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,CM_2,PDT
k141_2858_3	177437.HRM2_37210	3.33e-269	785.0	COG1749@1|root,COG1749@2|Bacteria,1MU5J@1224|Proteobacteria,42NGP@68525|delta/epsilon subdivisions,2WIZN@28221|Deltaproteobacteria,2MHUU@213118|Desulfobacterales	28221|Deltaproteobacteria	N	basal body rod protein	flgE	-	-	ko:K02390	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FlaE,Flg_bb_rod,Flg_bbr_C
k141_2858_4	1265505.ATUG01000001_gene3811	5.99e-66	220.0	COG1843@1|root,COG1843@2|Bacteria,1MXCG@1224|Proteobacteria,42U4T@68525|delta/epsilon subdivisions,2WQ5B@28221|Deltaproteobacteria,2MK0B@213118|Desulfobacterales	28221|Deltaproteobacteria	N	Required for flagellar hook formation. May act as a scaffolding protein	flgD	-	-	ko:K02389	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FLgD_tudor,FlgD,FlgD_ig
k141_868_1	1317122.ATO12_01310	6.22e-22	95.1	COG1357@1|root,COG1357@2|Bacteria,4NQ3B@976|Bacteroidetes,1I2VH@117743|Flavobacteriia,2YJ59@290174|Aquimarina	976|Bacteroidetes	S	Pentapeptide repeats (9 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Pentapeptide,Pentapeptide_4
k141_1973_1	338963.Pcar_1772	1.74e-06	48.5	COG0394@1|root,COG0394@2|Bacteria,1MWYQ@1224|Proteobacteria,42RQI@68525|delta/epsilon subdivisions,2WNEC@28221|Deltaproteobacteria,43V3P@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Low molecular weight phosphatase family	arsC	-	1.20.4.1	ko:K03741	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
k141_1973_2	314292.VAS14_04463	8.39e-78	240.0	COG0682@1|root,COG0682@2|Bacteria,1MVE3@1224|Proteobacteria,1RMVK@1236|Gammaproteobacteria,1XSP4@135623|Vibrionales	135623|Vibrionales	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
k141_2860_1	521011.Mpal_0766	2.27e-27	112.0	COG3593@1|root,arCOG03235@2157|Archaea,2Y7AF@28890|Euryarchaeota,2NAT2@224756|Methanomicrobia	224756|Methanomicrobia	L	Protein of unknown function (DUF2813)	-	-	-	ko:K07459	-	-	-	-	ko00000	-	-	-	AAA_15
k141_2860_2	1265505.ATUG01000001_gene4349	9.08e-51	173.0	COG0745@1|root,COG2197@1|root,COG0745@2|Bacteria,COG2197@2|Bacteria	2|Bacteria	K	response regulator	-	-	-	ko:K02282,ko:K07782,ko:K19135	ko02020,ko02024,ko02026,map02020,map02024,map02026	-	-	-	ko00000,ko00001,ko02035,ko02044,ko02048,ko03000	-	-	-	Cas_NE0113,GerE,Response_reg
k141_1974_1	469609.HMPREF0847_00312	1.24e-12	70.9	COG1131@1|root,COG1131@2|Bacteria,1TPBQ@1239|Firmicutes	1239|Firmicutes	V	'abc transporter, ATP-binding protein	bcrA	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
k141_3660_1	870967.VIS19158_06550	1.28e-172	484.0	COG2207@1|root,COG2207@2|Bacteria,1NGQN@1224|Proteobacteria,1SGF0@1236|Gammaproteobacteria,1XT4B@135623|Vibrionales	135623|Vibrionales	K	COG2207 AraC-type DNA-binding domain-containing proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
k141_3660_2	223926.28809790	1.86e-108	320.0	COG1762@1|root,COG1925@1|root,COG1762@2|Bacteria,COG1925@2|Bacteria,1NAXZ@1224|Proteobacteria,1SEUD@1236|Gammaproteobacteria,1XTFH@135623|Vibrionales	135623|Vibrionales	G	PTS system nitrogen regulatory IIA component	-	-	-	ko:K02806	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	-	-	-	PTS-HPr,PTS_EIIA_2
k141_3660_3	1444309.JAQG01000016_gene685	3.08e-20	91.7	COG1299@1|root,COG1445@1|root,COG1762@1|root,COG1299@2|Bacteria,COG1445@2|Bacteria,COG1762@2|Bacteria,1TPKU@1239|Firmicutes,4H9KR@91061|Bacilli,26QS4@186822|Paenibacillaceae	91061|Bacilli	G	PTS fructose transporter subunit IIC	fruA	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0008643,GO:0009401,GO:0015144,GO:0016020,GO:0016740,GO:0016772,GO:0016773,GO:0022804,GO:0022857,GO:0034219,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0090563	2.7.1.202	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	M00273	R03232	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.2.1	-	-	PTS_EIIA_2,PTS_EIIC,PTS_IIB
k141_1706_7	1219080.VEZ01S_37_00690	0.0	1096.0	COG1217@1|root,COG1217@2|Bacteria,1MV5Q@1224|Proteobacteria,1RMJB@1236|Gammaproteobacteria,1XTQJ@135623|Vibrionales	135623|Vibrionales	T	membrane GTPase involved in stress response	typA	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2
k141_1706_8	314292.VAS14_22994	3.9e-304	833.0	COG0174@1|root,COG0174@2|Bacteria,1MUGQ@1224|Proteobacteria,1RMD1@1236|Gammaproteobacteria,1XTYT@135623|Vibrionales	135623|Vibrionales	E	glutamine synthetase	glnA	GO:0003674,GO:0003824,GO:0004356,GO:0006082,GO:0006520,GO:0006541,GO:0006542,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016211,GO:0016874,GO:0016879,GO:0016880,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
k141_1706_9	55601.VANGNB10_cI0143c	2.36e-222	617.0	COG3852@1|root,COG3852@2|Bacteria,1MVN6@1224|Proteobacteria,1RN15@1236|Gammaproteobacteria,1XTJP@135623|Vibrionales	135623|Vibrionales	T	nitrogen regulation protein	glnL	-	2.7.13.3	ko:K07708	ko02020,map02020	M00497	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,PAS
k141_2384_1	1515746.HR45_08680	1.55e-22	97.4	COG0535@1|root,COG0535@2|Bacteria,1MWDC@1224|Proteobacteria,1RRMW@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	cofactor biosynthesis protein NifB	nifB	-	-	ko:K02585	-	-	-	-	ko00000	-	-	-	Fer4_14,Nitro_FeMo-Co,Radical_SAM
k141_2384_2	1116375.VEJY3_18856	9.44e-28	103.0	COG1145@1|root,COG1145@2|Bacteria,1QMDK@1224|Proteobacteria,1TJNE@1236|Gammaproteobacteria,1Y1FQ@135623|Vibrionales	135623|Vibrionales	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_2384_3	273057.SSO0193	1.33e-11	68.9	COG2078@1|root,arCOG01336@2157|Archaea,2XQG0@28889|Crenarchaeota	28889|Crenarchaeota	S	PFAM AMMECR1 domain protein	-	-	-	ko:K09141	-	-	-	-	ko00000	-	-	-	AMMECR1
k141_2384_4	323850.Shew_0931	2.9e-60	198.0	COG1355@1|root,COG1355@2|Bacteria,1MXK5@1224|Proteobacteria,1RQPK@1236|Gammaproteobacteria,2QARX@267890|Shewanellaceae	1236|Gammaproteobacteria	S	Belongs to the MEMO1 family	-	-	-	ko:K06990	-	-	-	-	ko00000,ko04812	-	-	-	AMMECR1,Memo
k141_2384_5	1517681.HW45_10015	8.64e-167	476.0	COG1180@1|root,COG1180@2|Bacteria,1R8XY@1224|Proteobacteria,1TH9J@1236|Gammaproteobacteria,1XSRS@135623|Vibrionales	135623|Vibrionales	H	radical SAM	-	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Radical_SAM
k141_2384_6	1056820.KB900674_gene2635	1.51e-33	125.0	2BDS5@1|root,327FW@2|Bacteria,1N15E@1224|Proteobacteria,1RSEH@1236|Gammaproteobacteria,2PP7N@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	S	NifQ	nifQ	-	-	ko:K15790	-	-	-	-	ko00000	-	-	-	NifQ
k141_2384_7	331678.Cphamn1_1080	9.68e-77	242.0	COG1237@1|root,COG1237@2|Bacteria	2|Bacteria	S	Metallo-beta-lactamase superfamily	-	-	2.5.1.105	ko:K06897	ko00790,map00790	-	R10339	RC00121	ko00000,ko00001,ko01000	-	-	-	Lactamase_B
k141_2384_8	1379281.AVAG01000014_gene1434	6.08e-37	128.0	COG1433@1|root,COG1433@2|Bacteria,1MZTM@1224|Proteobacteria,42U2B@68525|delta/epsilon subdivisions,2WQAQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM Dinitrogenase iron-molybdenum cofactor biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	Nitro_FeMo-Co
k141_2384_9	338966.Ppro_1951	4.99e-109	325.0	COG1149@1|root,COG1149@2|Bacteria,1MVPB@1224|Proteobacteria,42MJ5@68525|delta/epsilon subdivisions,2WJ9M@28221|Deltaproteobacteria,43SV7@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CbiA,Fer4
k141_2384_10	398767.Glov_1687	2.66e-76	241.0	COG1149@1|root,COG1149@2|Bacteria,1NCD9@1224|Proteobacteria,42PHV@68525|delta/epsilon subdivisions,2WKDZ@28221|Deltaproteobacteria,43U62@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CbiA,Fer4
k141_2384_11	765912.Thimo_3543	1.29e-46	162.0	COG1578@1|root,COG1578@2|Bacteria,1RI11@1224|Proteobacteria,1S1DR@1236|Gammaproteobacteria,1WWIA@135613|Chromatiales	135613|Chromatiales	S	Protein of unknown function DUF89	-	-	-	ko:K09116	-	-	-	-	ko00000	-	-	-	DUF89
k141_4095_1	1116375.VEJY3_21651	4.08e-208	583.0	COG0055@1|root,COG0055@2|Bacteria,1N6UZ@1224|Proteobacteria,1RNQW@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	-	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
k141_4095_3	472759.Nhal_1639	9.65e-263	756.0	COG1067@1|root,COG1067@2|Bacteria,1MWGB@1224|Proteobacteria,1RMPC@1236|Gammaproteobacteria,1WXPW@135613|Chromatiales	135613|Chromatiales	O	Belongs to the peptidase S16 family	-	-	-	-	-	-	-	-	-	-	-	-	AAA_32,Lon_C
k141_4095_4	1307437.J139_02915	1.05e-107	320.0	COG0583@1|root,COG0583@2|Bacteria,1MW16@1224|Proteobacteria,1RPNX@1236|Gammaproteobacteria,2Q0JN@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
k141_3074_1	933262.AXAM01000023_gene651	6.56e-130	398.0	COG0358@1|root,COG0358@2|Bacteria,1MUHC@1224|Proteobacteria,42MDZ@68525|delta/epsilon subdivisions,2WJ9Y@28221|Deltaproteobacteria,2MHRW@213118|Desulfobacterales	28221|Deltaproteobacteria	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2
k141_4776_1	1121396.KB892916_gene79	4.05e-50	182.0	COG0811@1|root,COG0811@2|Bacteria,1MX5J@1224|Proteobacteria,42NWR@68525|delta/epsilon subdivisions,2WK2E@28221|Deltaproteobacteria,2MI90@213118|Desulfobacterales	28221|Deltaproteobacteria	U	PFAM MotA TolQ ExbB proton channel	-	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	DUF3450,MotA_ExbB
k141_1707_1	933262.AXAM01000020_gene23	4.24e-170	491.0	COG0342@1|root,COG0342@2|Bacteria,1MV5U@1224|Proteobacteria,42M6V@68525|delta/epsilon subdivisions,2WJCI@28221|Deltaproteobacteria,2MHS8@213118|Desulfobacterales	28221|Deltaproteobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
k141_1708_1	1265505.ATUG01000001_gene3860	4.07e-09	58.2	COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,42P0M@68525|delta/epsilon subdivisions,2WJMC@28221|Deltaproteobacteria,2MJBK@213118|Desulfobacterales	28221|Deltaproteobacteria	I	PFAM AMP-dependent synthetase and ligase	-	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
k141_1708_2	879212.DespoDRAFT_03419	3.09e-15	70.1	COG1950@1|root,COG1950@2|Bacteria,1N1DF@1224|Proteobacteria,42TT1@68525|delta/epsilon subdivisions,2WQT0@28221|Deltaproteobacteria,2MKKQ@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Mycobacterial 4 TMS phage holin, superfamily IV	-	-	-	ko:K08972	-	-	-	-	ko00000	-	-	-	Phage_holin_4_2
k141_715_2	1265505.ATUG01000001_gene3956	5.4e-100	310.0	COG3434@1|root,COG3434@2|Bacteria,1MVW1@1224|Proteobacteria,42MIH@68525|delta/epsilon subdivisions,2WK3V@28221|Deltaproteobacteria,2MIQC@213118|Desulfobacterales	28221|Deltaproteobacteria	T	PFAM EAL domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,HDOD
k141_4112_1	1121405.dsmv_3258	4.37e-11	67.0	2DDGH@1|root,32U1F@2|Bacteria,1N0N4@1224|Proteobacteria,42TTB@68525|delta/epsilon subdivisions,2WQVT@28221|Deltaproteobacteria,2MKKK@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase
k141_4112_2	1121456.ATVA01000015_gene2433	2.21e-14	72.4	COG2309@1|root,COG2309@2|Bacteria,1MW2Y@1224|Proteobacteria,42P6P@68525|delta/epsilon subdivisions,2WJF8@28221|Deltaproteobacteria,2M90N@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	PFAM Peptidase M29, aminopeptidase II	-	-	-	ko:K19689	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M29
k141_4112_3	1304872.JAGC01000009_gene1370	3.34e-106	323.0	COG2309@1|root,COG2309@2|Bacteria,1MW2Y@1224|Proteobacteria,42P6P@68525|delta/epsilon subdivisions,2WJF8@28221|Deltaproteobacteria,2M90N@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	PFAM Peptidase M29, aminopeptidase II	-	-	-	ko:K19689	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M29
k141_4112_4	1304885.AUEY01000066_gene1298	4.94e-19	80.9	2EBS7@1|root,335S2@2|Bacteria,1NBWR@1224|Proteobacteria,42WCA@68525|delta/epsilon subdivisions,2WRUH@28221|Deltaproteobacteria,2MKKJ@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_4112_5	177437.HRM2_17650	7.94e-40	148.0	COG2267@1|root,COG2267@2|Bacteria,1MWDA@1224|Proteobacteria,42Z3P@68525|delta/epsilon subdivisions,2WUNY@28221|Deltaproteobacteria,2MN81@213118|Desulfobacterales	28221|Deltaproteobacteria	I	Alpha/beta hydrolase family	-	-	3.1.1.5	ko:K01048	ko00564,map00564	-	-	-	ko00000,ko00001,ko01000	-	-	-	Hydrolase_4
k141_716_1	1121413.JMKT01000015_gene313	4.88e-40	151.0	COG0642@1|root,COG2202@1|root,COG2203@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,43ED4@68525|delta/epsilon subdivisions,2X81C@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4,PAS_9,Response_reg
k141_368_1	400668.Mmwyl1_0470	1.44e-70	220.0	COG4126@1|root,COG4126@2|Bacteria,1MVNB@1224|Proteobacteria,1RQXU@1236|Gammaproteobacteria,1XJPJ@135619|Oceanospirillales	135619|Oceanospirillales	E	Racemase	-	-	5.1.99.3	ko:K16841	ko00230,ko01120,map00230,map01120	-	R03925	RC01027	ko00000,ko00001,ko01000	-	-	-	Asp_Glu_race
k141_368_2	1208321.D104_08365	1.64e-97	290.0	COG1802@1|root,COG1802@2|Bacteria,1R96W@1224|Proteobacteria,1SZ8T@1236|Gammaproteobacteria,1XR7A@135619|Oceanospirillales	135619|Oceanospirillales	K	FCD	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
k141_368_3	400668.Mmwyl1_0472	1.04e-248	691.0	COG1953@1|root,COG1953@2|Bacteria,1MV18@1224|Proteobacteria,1RMZU@1236|Gammaproteobacteria,1XN2Z@135619|Oceanospirillales	135619|Oceanospirillales	FH	Permease for cytosine purines, uracil, thiamine, allantoin	-	-	-	ko:K03457	-	-	-	-	ko00000	2.A.39	-	-	Transp_cyt_pur
k141_718_2	870967.VIS19158_19642	2.63e-100	301.0	COG0115@1|root,COG0115@2|Bacteria,1MZAK@1224|Proteobacteria,1RPPG@1236|Gammaproteobacteria,1XSWU@135623|Vibrionales	135623|Vibrionales	EH	COG0115 Branched-chain amino acid aminotransferase 4-amino-4-deoxychorismate lyase	pabC	GO:0003674,GO:0003824,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0008696,GO:0009987,GO:0016829,GO:0016830,GO:0016833,GO:0019752,GO:0034641,GO:0042558,GO:0043436,GO:0043603,GO:0044237,GO:0044281,GO:0046483,GO:0051186,GO:0071704,GO:1901360,GO:1901564	4.1.3.38	ko:K02619	ko00790,map00790	-	R05553	RC01843,RC02148	ko00000,ko00001,ko01000	-	-	-	Aminotran_4
k141_2051_1	396588.Tgr7_1721	6.84e-26	106.0	COG1509@1|root,COG1509@2|Bacteria,1MUPJ@1224|Proteobacteria,1RRI0@1236|Gammaproteobacteria,1WX76@135613|Chromatiales	135613|Chromatiales	E	lysine 2,3-aminomutase	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_2051_2	1304885.AUEY01000005_gene831	5.73e-55	175.0	COG0838@1|root,COG0838@2|Bacteria,1PPP3@1224|Proteobacteria,42VF4@68525|delta/epsilon subdivisions,2WRIV@28221|Deltaproteobacteria,2MMCP@213118|Desulfobacterales	28221|Deltaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain	nuoA	-	1.6.5.3	ko:K00330	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q4
k141_2051_3	1304885.AUEY01000005_gene832	3.95e-97	286.0	COG0377@1|root,COG0377@2|Bacteria,1MUI2@1224|Proteobacteria,42MDJ@68525|delta/epsilon subdivisions,2WNNV@28221|Deltaproteobacteria,2MNCS@213118|Desulfobacterales	28221|Deltaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoB	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
k141_2051_4	264201.pc0561	7.8e-07	53.9	COG0852@1|root,COG0852@2|Bacteria,2JGZJ@204428|Chlamydiae	204428|Chlamydiae	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoC	-	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa
k141_2051_5	880072.Desac_1203	7.93e-156	450.0	COG0649@1|root,COG0649@2|Bacteria,1MVIN@1224|Proteobacteria,42M9G@68525|delta/epsilon subdivisions,2WIS7@28221|Deltaproteobacteria,2MQ5T@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0016020,GO:0044424,GO:0044464,GO:0071944	1.6.5.3	ko:K00333,ko:K13378	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa,Complex1_49kDa
k141_2051_6	1304885.AUEY01000005_gene835	6.26e-147	424.0	COG1005@1|root,COG1005@2|Bacteria,1MU2R@1224|Proteobacteria,42MMX@68525|delta/epsilon subdivisions,2WIX8@28221|Deltaproteobacteria,2MJHM@213118|Desulfobacterales	28221|Deltaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	nuoH	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
k141_2051_7	1121403.AUCV01000012_gene4037	5.37e-42	143.0	COG1143@1|root,COG1143@2|Bacteria,1MV90@1224|Proteobacteria,42SZV@68525|delta/epsilon subdivisions,2WP8T@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoI	-	1.6.5.3	ko:K00338,ko:K05580	ko00190,ko01100,map00190,map01100	M00144,M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer4,Fer4_4,Fer4_7
k141_2051_8	1304885.AUEY01000005_gene837	3.27e-54	176.0	COG0839@1|root,COG0839@2|Bacteria,1PJW9@1224|Proteobacteria,42V0F@68525|delta/epsilon subdivisions,2WS8G@28221|Deltaproteobacteria,2MNWY@213118|Desulfobacterales	28221|Deltaproteobacteria	C	NADH-ubiquinone/plastoquinone oxidoreductase chain 6	nuoJ	-	1.6.5.3	ko:K00339	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q3
k141_2051_9	880072.Desac_1207	1.07e-27	103.0	COG0713@1|root,COG0713@2|Bacteria,1RH0S@1224|Proteobacteria,42UWR@68525|delta/epsilon subdivisions,2WQRB@28221|Deltaproteobacteria,2MQNF@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoK	-	1.6.5.3	ko:K00340,ko:K05576	ko00190,ko01100,map00190,map01100	M00144,M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q2
k141_2051_10	1304885.AUEY01000005_gene839	1.56e-235	662.0	COG0651@1|root,COG0651@2|Bacteria,1QU5Z@1224|Proteobacteria,42MDX@68525|delta/epsilon subdivisions,2WJ56@28221|Deltaproteobacteria,2MIB7@213118|Desulfobacterales	28221|Deltaproteobacteria	CP	PFAM NADH Ubiquinone plastoquinone (complex I)	-	-	-	ko:K05568	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	Proton_antipo_M,Proton_antipo_N
k141_2051_12	1304885.AUEY01000005_gene841	1.88e-21	95.1	COG0651@1|root,COG0651@2|Bacteria,1MV6V@1224|Proteobacteria,42MSA@68525|delta/epsilon subdivisions,2WIS1@28221|Deltaproteobacteria,2MHQ9@213118|Desulfobacterales	28221|Deltaproteobacteria	CP	plastoquinone (complex I)	-	-	-	ko:K05568,ko:K12137	-	-	-	-	ko00000,ko01000,ko02000	2.A.63.1,2.A.63.2	-	-	Proton_antipo_M
k141_2741_1	536232.CLM_2327	1.75e-20	92.0	COG1012@1|root,COG1012@2|Bacteria,1UHQT@1239|Firmicutes,25E5E@186801|Clostridia	186801|Clostridia	C	acetaldehyde dehydrogenase (acetylating)	-	-	-	-	-	-	-	-	-	-	-	-	Aldedh
k141_2741_2	1121451.DESAM_21354	0.0	1431.0	COG1882@1|root,COG1882@2|Bacteria,1MWBF@1224|Proteobacteria,42M5J@68525|delta/epsilon subdivisions,2WJAK@28221|Deltaproteobacteria,2M9FS@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	Glycine radical	cutC	GO:0001505,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006576,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009308,GO:0009310,GO:0009987,GO:0016829,GO:0016840,GO:0019695,GO:0033265,GO:0034641,GO:0042133,GO:0042135,GO:0042165,GO:0042402,GO:0042426,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0044106,GO:0044237,GO:0044248,GO:0046983,GO:0065007,GO:0065008,GO:0070405,GO:0071704,GO:0097164,GO:1901564,GO:1901565,GO:1901575	4.3.99.4	ko:K20038	-	-	-	-	ko00000,ko01000	-	-	-	Gly_radical,PFL-like
k141_2741_3	748727.CLJU_c39820	4.75e-178	501.0	COG1180@1|root,COG1180@2|Bacteria,1TRFU@1239|Firmicutes,25CC6@186801|Clostridia,36WTB@31979|Clostridiaceae	186801|Clostridia	C	Catalyzes activation of the choline trimethylamine-lyase CutC under anaerobic conditions by generation of an organic free radical on a glycine residue, via an homolytic cleavage of S- adenosyl-L-methionine (SAM)	cutD	-	-	ko:K20037	-	-	-	-	ko00000,ko01000	-	-	-	Fer4,Fer4_12,Fer4_7,Fer4_9,Radical_SAM
k141_2741_4	1298920.KI911353_gene4600	5.82e-57	186.0	COG4766@1|root,COG4766@2|Bacteria,1V4U8@1239|Firmicutes,24807@186801|Clostridia,21ZQR@1506553|Lachnoclostridium	186801|Clostridia	E	Ethanolamine utilisation protein EutQ	-	-	-	ko:K04030	-	-	-	-	ko00000	-	-	-	EutQ
k141_2741_5	748727.CLJU_c39740	3.91e-24	105.0	COG4577@1|root,COG4577@2|Bacteria,1V947@1239|Firmicutes,24CB3@186801|Clostridia,36GMY@31979|Clostridiaceae	186801|Clostridia	CQ	BMC	-	-	-	-	-	-	-	-	-	-	-	-	BMC
k141_2741_6	207559.Dde_3279	7.4e-259	720.0	COG1012@1|root,COG1012@2|Bacteria,1QUBI@1224|Proteobacteria,42R00@68525|delta/epsilon subdivisions,2WN3T@28221|Deltaproteobacteria,2M9FQ@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	Aldehyde dehydrogenase family	-	-	1.1.1.1,1.2.1.10	ko:K00001,ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00228,R00623,R00754,R01172,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00004,RC00050,RC00087,RC00088,RC00099,RC00116,RC00184,RC00649,RC01195,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	Aldedh
k141_2741_7	1121445.ATUZ01000013_gene1108	1.28e-46	151.0	COG4577@1|root,COG4577@2|Bacteria,1RH1U@1224|Proteobacteria,42U8T@68525|delta/epsilon subdivisions,2WQCF@28221|Deltaproteobacteria,2MBZH@213115|Desulfovibrionales	28221|Deltaproteobacteria	CQ	PFAM microcompartments protein	-	-	-	-	-	-	-	-	-	-	-	-	BMC
k141_2741_8	37659.JNLN01000001_gene467	7.7e-58	191.0	COG4812@1|root,COG4812@2|Bacteria,1V18U@1239|Firmicutes,24D11@186801|Clostridia,36H7A@31979|Clostridiaceae	186801|Clostridia	E	Cobalamin adenosyltransferase	eutT	-	2.5.1.17	ko:K04032	ko00860,ko01100,map00860,map01100	-	R01492	RC00533	ko00000,ko00001,ko01000	-	-	-	Cob_adeno_trans
k141_2741_9	207559.Dde_3276	1.94e-102	303.0	COG4869@1|root,COG4869@2|Bacteria,1QX2Q@1224|Proteobacteria,43BW4@68525|delta/epsilon subdivisions,2X76T@28221|Deltaproteobacteria,2MAK7@213115|Desulfovibrionales	28221|Deltaproteobacteria	Q	Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate	-	-	-	-	-	-	-	-	-	-	-	-	PTAC
k141_2741_10	526222.Desal_0474	4.66e-146	417.0	COG4820@1|root,COG4820@2|Bacteria,1MVXX@1224|Proteobacteria,42RX2@68525|delta/epsilon subdivisions,2WNFA@28221|Deltaproteobacteria,2MA4S@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	ethanolamine utilization protein	-	-	-	ko:K04024	-	-	-	-	ko00000	-	-	-	MreB_Mbl,PilM_2
k141_2741_11	37659.JNLN01000001_gene464	0.000124	49.7	2E7RK@1|root,3326X@2|Bacteria,1VEHH@1239|Firmicutes,24JHV@186801|Clostridia,36MBY@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_1042_1	1188252.AJYK01000121_gene1292	1.38e-17	82.4	COG1053@1|root,COG1053@2|Bacteria,1MU5M@1224|Proteobacteria,1RMU2@1236|Gammaproteobacteria,1XSH4@135623|Vibrionales	135623|Vibrionales	C	fumarate reductase, flavoprotein subunit	frdA	-	1.3.5.4	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	M00009,M00011,M00150,M00173	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
k141_1042_2	243277.VC_2127	2.32e-57	184.0	COG1580@1|root,COG1580@2|Bacteria,1RG10@1224|Proteobacteria,1S7UD@1236|Gammaproteobacteria,1XX17@135623|Vibrionales	135623|Vibrionales	N	Controls the rotational direction of flagella during chemotaxis	fliL	-	-	ko:K02415	-	-	-	-	ko00000,ko02035	-	-	-	FliL
k141_1042_4	1187848.AJYQ01000115_gene739	1.34e-79	238.0	COG1886@1|root,COG1886@2|Bacteria,1RGWT@1224|Proteobacteria,1S5YE@1236|Gammaproteobacteria,1XWWS@135623|Vibrionales	135623|Vibrionales	N	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation	fliN	-	-	ko:K02417	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	FliMN_C
k141_1042_5	55601.VANGNB10_cI1930c	8.52e-38	131.0	COG3190@1|root,COG3190@2|Bacteria,1PQ31@1224|Proteobacteria,1SGKN@1236|Gammaproteobacteria,1XY0C@135623|Vibrionales	135623|Vibrionales	N	COG3190 Flagellar biogenesis protein	fliO	-	-	ko:K02418	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	FliO
k141_1042_7	1051646.VITU9109_12553	3.55e-46	149.0	COG1987@1|root,COG1987@2|Bacteria,1N73W@1224|Proteobacteria,1SCBG@1236|Gammaproteobacteria,1XXW8@135623|Vibrionales	135623|Vibrionales	N	Role in flagellar biosynthesis	fliQ	-	-	ko:K02420	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	Bac_export_3
k141_1042_8	55601.VANGNB10_cI1927c	4.9e-133	383.0	COG1684@1|root,COG1684@2|Bacteria,1NIF4@1224|Proteobacteria,1RMYW@1236|Gammaproteobacteria,1XTE8@135623|Vibrionales	135623|Vibrionales	N	Role in flagellar biosynthesis	fliR	-	-	ko:K02421	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	Bac_export_1
k141_1042_9	675806.VII_001707	1.28e-209	586.0	COG1377@1|root,COG1377@2|Bacteria,1MUWI@1224|Proteobacteria,1RMHA@1236|Gammaproteobacteria,1XTM7@135623|Vibrionales	135623|Vibrionales	N	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin	flhB	-	-	ko:K02401	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	Bac_export_2
k141_1042_10	674977.VMC_12010	1.97e-98	289.0	COG2840@1|root,COG2840@2|Bacteria,1MVS6@1224|Proteobacteria,1RPXD@1236|Gammaproteobacteria,1XUS2@135623|Vibrionales	135623|Vibrionales	S	Belongs to the UPF0115 family	yfcN	-	-	-	-	-	-	-	-	-	-	-	Smr
k141_1042_11	945550.VISI1226_11254	2.79e-203	565.0	COG2890@1|root,COG2890@2|Bacteria,1MX8Q@1224|Proteobacteria,1RPHQ@1236|Gammaproteobacteria,1XUD9@135623|Vibrionales	135623|Vibrionales	J	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue	prmB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006304,GO:0006305,GO:0006306,GO:0006464,GO:0006479,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009007,GO:0009008,GO:0009987,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0032259,GO:0032775,GO:0034641,GO:0036009,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0044728,GO:0046483,GO:0071704,GO:0090304,GO:0140096,GO:0140097,GO:1901360,GO:1901564	2.1.1.298	ko:K07320	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03009	-	-	-	MTS
k141_1042_12	1348635.BBJY01000007_gene246	5.09e-227	629.0	COG0082@1|root,COG0082@2|Bacteria,1MU98@1224|Proteobacteria,1RMQS@1236|Gammaproteobacteria,1XSRC@135623|Vibrionales	135623|Vibrionales	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_synt
k141_1042_13	223926.28807191	2.5e-30	109.0	2CJ8F@1|root,32SAV@2|Bacteria,1N0DT@1224|Proteobacteria,1S9BA@1236|Gammaproteobacteria,1XYEK@135623|Vibrionales	135623|Vibrionales	S	YfcL protein	-	-	-	-	-	-	-	-	-	-	-	-	YfcL
k141_1042_14	1219065.VPR01S_13_00880	5.42e-37	125.0	COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,1SCA7@1236|Gammaproteobacteria,1XYBB@135623|Vibrionales	135623|Vibrionales	K	COG1278 Cold shock proteins	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
k141_1042_15	1238450.VIBNISOn1_1750032	8.54e-20	98.6	COG2931@1|root,2ZQV3@2|Bacteria,1P9CB@1224|Proteobacteria	1224|Proteobacteria	Q	RTX toxins and related Ca2 -binding	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_1042_16	675814.VIC_001845	0.0	902.0	COG0665@1|root,COG4121@1|root,COG0665@2|Bacteria,COG4121@2|Bacteria,1MZW5@1224|Proteobacteria,1RMTE@1236|Gammaproteobacteria,1XSRW@135623|Vibrionales	135623|Vibrionales	J	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34	mnmC	GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0003824,GO:0004808,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016491,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0055114,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.1.1.61	ko:K15461	-	-	R00601,R08702	RC00003,RC00053,RC00060,RC01483	ko00000,ko01000,ko03016	-	-	-	DAO,Methyltransf_30
k141_1042_17	1116375.VEJY3_11315	2.29e-258	712.0	COG0304@1|root,COG0304@2|Bacteria,1MU1X@1224|Proteobacteria,1RMDE@1236|Gammaproteobacteria,1XT7W@135623|Vibrionales	135623|Vibrionales	IQ	Belongs to the beta-ketoacyl-ACP synthases family	fabB	-	2.3.1.41	ko:K00647	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
k141_1042_18	243277.VC_2108	3.32e-209	586.0	COG0111@1|root,COG0111@2|Bacteria,1N5TD@1224|Proteobacteria,1RMFW@1236|Gammaproteobacteria,1XSPZ@135623|Vibrionales	135623|Vibrionales	H	Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate	pdxB	GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	1.1.1.290	ko:K03473	ko00750,ko01100,map00750,map01100	M00124	R04210	RC00084	ko00000,ko00001,ko00002,ko01000	-	-	-	2-Hacid_dh,2-Hacid_dh_C,DUF3410
k141_1042_19	55601.VANGNB10_cI1915c	4.4e-209	582.0	COG0136@1|root,COG0136@2|Bacteria,1MUHG@1224|Proteobacteria,1RNB6@1236|Gammaproteobacteria,1XT9P@135623|Vibrionales	135623|Vibrionales	E	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate	asd	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004073,GO:0006082,GO:0006520,GO:0006549,GO:0006553,GO:0006555,GO:0006566,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009081,GO:0009082,GO:0009085,GO:0009086,GO:0009088,GO:0009089,GO:0009097,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
k141_1042_20	243277.VC_2106	4.89e-95	278.0	COG0735@1|root,COG0735@2|Bacteria,1RDWJ@1224|Proteobacteria,1S4H7@1236|Gammaproteobacteria,1XUH6@135623|Vibrionales	135623|Vibrionales	K	Belongs to the Fur family	fur	GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
k141_1042_21	314292.VAS14_17686	3.7e-116	333.0	COG0716@1|root,COG0716@2|Bacteria,1MX7F@1224|Proteobacteria,1RMNT@1236|Gammaproteobacteria,1XT3A@135623|Vibrionales	135623|Vibrionales	C	Low-potential electron donor to a number of redox enzymes	fldA	-	-	ko:K03839	-	-	-	-	ko00000	-	-	-	Flavodoxin_1
k141_1042_22	674977.VMC_15620	4.07e-95	286.0	COG2267@1|root,COG2267@2|Bacteria,1QUFS@1224|Proteobacteria,1T1XF@1236|Gammaproteobacteria,1XV01@135623|Vibrionales	135623|Vibrionales	I	PGAP1-like protein	-	-	-	ko:K01175	-	-	-	-	ko00000,ko01000	-	-	-	Abhydrolase_1,Abhydrolase_6
k141_1042_23	55601.VANGNB10_cI1906c	4.53e-83	250.0	COG3057@1|root,COG3057@2|Bacteria,1MUW8@1224|Proteobacteria,1RQ83@1236|Gammaproteobacteria,1XVQ2@135623|Vibrionales	135623|Vibrionales	L	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated	seqA	GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0006275,GO:0008150,GO:0008156,GO:0009889,GO:0009890,GO:0009892,GO:0010556,GO:0010558,GO:0010605,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0043565,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1990837,GO:2000112,GO:2000113	-	ko:K03645	-	-	-	-	ko00000,ko03032,ko03036	-	-	-	SeqA,SeqA_N
k141_1042_25	1348635.BBJY01000007_gene224	2.76e-88	269.0	COG3782@1|root,COG3782@2|Bacteria,1N971@1224|Proteobacteria,1SD24@1236|Gammaproteobacteria,1XSBE@135623|Vibrionales	135623|Vibrionales	S	protein conserved in bacteria	-	-	-	ko:K09977	-	-	-	-	ko00000	-	-	-	DUF1853
k141_1042_26	1348635.BBJY01000007_gene223	2.96e-140	400.0	COG0327@1|root,COG0327@2|Bacteria,1MVUN@1224|Proteobacteria,1RNBU@1236|Gammaproteobacteria,1XUIZ@135623|Vibrionales	135623|Vibrionales	S	NIF3 (NGG1p interacting factor 3)	ybgI	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	-	-	-	-	-	-	-	-	-	NIF3
k141_1042_27	55601.VANGNB10_cI1902	3.73e-300	820.0	COG0372@1|root,COG0372@2|Bacteria,1MUKX@1224|Proteobacteria,1RNDK@1236|Gammaproteobacteria,1XSCA@135623|Vibrionales	135623|Vibrionales	C	Belongs to the citrate synthase family	gltA	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
k141_1042_28	583345.Mmol_0757	1.16e-08	56.6	COG2009@1|root,COG2009@2|Bacteria,1RIGZ@1224|Proteobacteria,2VWRY@28216|Betaproteobacteria,2KN5Q@206350|Nitrosomonadales	206350|Nitrosomonadales	C	TIGRFAM succinate dehydrogenase, cytochrome b556 subunit	-	-	-	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	Sdh_cyt
k141_1042_29	55601.VANGNB10_cI1900c	1.23e-35	125.0	COG2142@1|root,COG2142@2|Bacteria,1MZR9@1224|Proteobacteria,1S9TS@1236|Gammaproteobacteria,1XX9X@135623|Vibrionales	135623|Vibrionales	C	Membrane-anchoring subunit of succinate dehydrogenase (SDH)	sdhD	-	-	ko:K00242	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	Sdh_cyt
k141_1042_30	945543.VIBR0546_20535	6.88e-286	797.0	COG1053@1|root,COG1053@2|Bacteria,1MU5M@1224|Proteobacteria,1RMU2@1236|Gammaproteobacteria,1XUJA@135623|Vibrionales	135623|Vibrionales	C	Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily	sdhA	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
k141_1042_31	298386.PBPRA1047	4.73e-117	340.0	COG0479@1|root,COG0479@2|Bacteria,1MVHS@1224|Proteobacteria,1RNWR@1236|Gammaproteobacteria,1XSXW@135623|Vibrionales	135623|Vibrionales	C	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family	sdhB	-	1.3.5.1,1.3.5.4	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_3,Fer4_17
k141_1042_32	1348635.BBJY01000007_gene217	0.0	1601.0	COG0567@1|root,COG0567@2|Bacteria,1MVBF@1224|Proteobacteria,1RN8K@1236|Gammaproteobacteria,1XUQD@135623|Vibrionales	135623|Vibrionales	C	COG0567 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes	sucA	-	1.2.4.2	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R00621,R01933,R01940,R03316,R08549	RC00004,RC00027,RC00627,RC02743,RC02833,RC02883	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr
k141_1042_33	675813.VIB_000807	1.32e-225	629.0	COG0508@1|root,COG0508@2|Bacteria,1MUJD@1224|Proteobacteria,1RME0@1236|Gammaproteobacteria,1XTKP@135623|Vibrionales	135623|Vibrionales	C	The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)	sucB	-	2.3.1.61	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R02570,R02571,R08549	RC00004,RC02727,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
k141_1042_34	675817.VDA_002499	1.25e-216	605.0	COG0045@1|root,COG0045@2|Bacteria,1MVCE@1224|Proteobacteria,1RMSU@1236|Gammaproteobacteria,1XTU2@135623|Vibrionales	135623|Vibrionales	F	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit	sucC	GO:0003674,GO:0003824,GO:0004774,GO:0004775,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016874,GO:0016877,GO:0016878,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350	6.2.1.5	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,Ligase_CoA
k141_1042_35	29495.EA26_05085	1.92e-184	515.0	COG0074@1|root,COG0074@2|Bacteria,1MUGA@1224|Proteobacteria,1RM7Y@1236|Gammaproteobacteria,1XSTF@135623|Vibrionales	135623|Vibrionales	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit	sucD	-	6.2.1.5	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_binding,Ligase_CoA
k141_1042_36	1348635.BBJY01000007_gene213	1.29e-127	369.0	COG1108@1|root,COG1108@2|Bacteria,1MVC2@1224|Proteobacteria,1RPYF@1236|Gammaproteobacteria,1XTAW@135623|Vibrionales	135623|Vibrionales	P	COG1108 ABC-type Mn2 Zn2 transport systems, permease components	znuB	-	-	ko:K09816	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ABC-3
k141_1042_37	675813.VIB_000813	2.61e-119	348.0	COG1121@1|root,COG1121@2|Bacteria,1MUDW@1224|Proteobacteria,1RPJT@1236|Gammaproteobacteria,1XTI4@135623|Vibrionales	135623|Vibrionales	P	Part of the ABC transporter complex ZnuABC involved in zinc import. Responsible for energy coupling to the transport system	znuC	GO:0000041,GO:0003674,GO:0003824,GO:0005215,GO:0005385,GO:0006810,GO:0006811,GO:0006812,GO:0006829,GO:0008150,GO:0008324,GO:0015075,GO:0015318,GO:0015399,GO:0015405,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0042623,GO:0042626,GO:0043492,GO:0046873,GO:0046915,GO:0051179,GO:0051234,GO:0055085,GO:0070838,GO:0071577,GO:0072509,GO:0072511,GO:0098655,GO:0098660,GO:0098662	-	ko:K09817	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ABC_tran
k141_1042_38	675813.VIB_000814	1.02e-104	314.0	COG4531@1|root,COG4531@2|Bacteria,1QTTI@1224|Proteobacteria,1RMRJ@1236|Gammaproteobacteria,1XT4D@135623|Vibrionales	135623|Vibrionales	P	COG4531 ABC-type Zn2 transport system, periplasmic component surface adhesin	znuA	-	-	ko:K09815	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ZnuA
k141_1042_39	55601.VANGNB10_cI1889c	5.19e-28	102.0	COG1918@1|root,COG1918@2|Bacteria,1Q29A@1224|Proteobacteria,1SGFM@1236|Gammaproteobacteria,1XYYK@135623|Vibrionales	135623|Vibrionales	P	Fe2 transport system protein A	feoA	-	-	ko:K04758	-	-	-	-	ko00000,ko02000	-	-	-	FeoA
k141_1042_40	55601.VANGNB10_cI1888c	0.0	1135.0	COG0370@1|root,COG0370@2|Bacteria,1MUZC@1224|Proteobacteria,1RME9@1236|Gammaproteobacteria,1XSYA@135623|Vibrionales	135623|Vibrionales	P	transporter of a GTP-driven Fe(2 ) uptake system	feoB	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoB_C,FeoB_N,Gate
k141_1042_41	675813.VIB_000817	1.03e-23	92.0	2EGR8@1|root,33AHD@2|Bacteria,1QTRG@1224|Proteobacteria,1SUI3@1236|Gammaproteobacteria,1XYXP@135623|Vibrionales	135623|Vibrionales	S	FeoC like transcriptional regulator	VV1042	-	-	ko:K10123	-	-	-	-	ko00000,ko02000	-	-	-	FeoC
k141_1042_42	1121943.KB899993_gene27	2.05e-113	340.0	COG1638@1|root,COG1638@2|Bacteria,1MWAM@1224|Proteobacteria,1S0ZS@1236|Gammaproteobacteria,1XH49@135619|Oceanospirillales	135619|Oceanospirillales	G	transporter	-	-	-	-	-	-	-	-	-	-	-	-	DctP
k141_3202_2	887062.HGR_16710	2.47e-52	179.0	COG2230@1|root,COG2230@2|Bacteria,1MX3U@1224|Proteobacteria,2VIPR@28216|Betaproteobacteria,4AA3P@80864|Comamonadaceae	28216|Betaproteobacteria	M	PFAM Cyclopropane-fatty-acyl-phospholipid synthase	cfa2	-	2.1.1.79	ko:K00574	-	-	-	-	ko00000,ko01000	-	-	-	CMAS
k141_3202_4	983545.Glaag_2808	1.04e-83	251.0	COG0494@1|root,COG0494@2|Bacteria,1PC5J@1224|Proteobacteria,1S267@1236|Gammaproteobacteria,466TG@72275|Alteromonadaceae	1236|Gammaproteobacteria	L	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
k141_3202_5	1348635.BBJY01000003_gene3861	8.67e-105	317.0	COG2988@1|root,COG2988@2|Bacteria,1MW1T@1224|Proteobacteria,1RQPG@1236|Gammaproteobacteria,1XU9R@135623|Vibrionales	135623|Vibrionales	E	Belongs to the AspA AstE family. Succinylglutamate desuccinylase subfamily	-	-	-	-	-	-	-	-	-	-	-	-	AstE_AspA
k141_3202_6	675813.VIB_002620	1.06e-220	620.0	COG3724@1|root,COG3724@2|Bacteria,1MUJV@1224|Proteobacteria,1RNSS@1236|Gammaproteobacteria,1XVMD@135623|Vibrionales	135623|Vibrionales	E	Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2)	astB	-	3.5.3.23	ko:K01484	ko00330,ko01100,map00330,map01100	-	R04189	RC00024	ko00000,ko00001,ko01000	-	-	-	AstB
k141_3202_7	932213.SPM24T3_03477	1.26e-106	323.0	COG1012@1|root,COG1012@2|Bacteria,1MV2I@1224|Proteobacteria,1RPQW@1236|Gammaproteobacteria,400VC@613|Serratia	1236|Gammaproteobacteria	C	Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate	astD	GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016491,GO:0016620,GO:0016903,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0055114,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	1.2.1.71	ko:K06447	ko00330,ko01100,map00330,map01100	-	R05049	RC00080	ko00000,ko00001,ko01000	-	-	-	Aldedh
k141_3202_8	1283284.AZUK01000001_gene153	4.5e-110	332.0	COG1012@1|root,COG1012@2|Bacteria,1MV2I@1224|Proteobacteria,1RPQW@1236|Gammaproteobacteria,1Y3FQ@135624|Aeromonadales	135624|Aeromonadales	C	Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate	astD	-	1.2.1.71	ko:K06447	ko00330,ko01100,map00330,map01100	-	R05049	RC00080	ko00000,ko00001,ko01000	-	-	-	Aldedh
k141_3202_9	1348635.BBJY01000003_gene3859	3.11e-188	530.0	COG3138@1|root,COG3138@2|Bacteria,1MWHC@1224|Proteobacteria,1RMXG@1236|Gammaproteobacteria,1XU0Z@135623|Vibrionales	135623|Vibrionales	E	Arginine N-succinyltransferase beta subunit	-	-	2.3.1.109	ko:K00673	ko00330,ko01100,map00330,map01100	-	R00832	RC00004,RC00064	ko00000,ko00001,ko01000	-	-	-	AstA
k141_3202_10	1188252.AJYK01000114_gene1593	1.02e-59	196.0	COG3138@1|root,COG3138@2|Bacteria,1NMVM@1224|Proteobacteria,1RSGX@1236|Gammaproteobacteria,1Y0FW@135623|Vibrionales	135623|Vibrionales	E	Arginine N-succinyltransferase beta subunit	-	-	-	-	-	-	-	-	-	-	-	-	AstA
k141_3202_11	1348635.BBJY01000003_gene3858	2.52e-78	243.0	COG3138@1|root,COG3138@2|Bacteria,1NMVM@1224|Proteobacteria,1RSGX@1236|Gammaproteobacteria,1Y0FW@135623|Vibrionales	135623|Vibrionales	E	Arginine N-succinyltransferase beta subunit	-	-	-	-	-	-	-	-	-	-	-	-	AstA
k141_3202_12	1286170.RORB6_08560	7.44e-29	114.0	COG4992@1|root,COG4992@2|Bacteria,1MV3C@1224|Proteobacteria,1RMV1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	aminotransferase	argD	GO:0003674,GO:0003824,GO:0003992,GO:0004069,GO:0005488,GO:0005515,GO:0006082,GO:0006105,GO:0006520,GO:0006525,GO:0006526,GO:0006527,GO:0006591,GO:0006593,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009064,GO:0009065,GO:0009084,GO:0009987,GO:0016053,GO:0016054,GO:0016740,GO:0016769,GO:0017144,GO:0019545,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0042450,GO:0042802,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043825,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0046394,GO:0046395,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607	2.6.1.11,2.6.1.17,2.6.1.81	ko:K00821,ko:K00840	ko00220,ko00300,ko00330,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map00330,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04217,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	iAPECO1_1312.APECO1_817,iEC55989_1330.EC55989_1916,iECABU_c1320.ECABU_c20050,iECED1_1282.ECED1_1950,iECOK1_1307.ECOK1_1868,iECP_1309.ECP_1694,iECS88_1305.ECS88_1800,iEcSMS35_1347.EcSMS35_1443,iUMN146_1321.UM146_08405,iUTI89_1310.UTI89_C1943,ic_1306.c2148	Aminotran_3
k141_218_1	1304875.JAFZ01000001_gene1045	1.65e-53	182.0	COG5438@1|root,COG5438@2|Bacteria,3TA8P@508458|Synergistetes	508458|Synergistetes	S	PFAM YibE F family protein	-	-	-	-	-	-	-	-	-	-	-	-	YibE_F
k141_3877_1	1348635.BBJY01000007_gene162	0.0	1464.0	2AX8M@1|root,31P7F@2|Bacteria,1QKX6@1224|Proteobacteria,1TJ33@1236|Gammaproteobacteria,1Y0EF@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_3877_2	1517681.HW45_07130	2.28e-66	209.0	2AXFM@1|root,31PF5@2|Bacteria,1QM4X@1224|Proteobacteria,1TJCR@1236|Gammaproteobacteria,1Y10Y@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_3877_3	1348635.BBJY01000007_gene160	2.96e-92	275.0	2DNGS@1|root,32XES@2|Bacteria,1NCMU@1224|Proteobacteria,1SBMP@1236|Gammaproteobacteria,1XX1C@135623|Vibrionales	135623|Vibrionales	S	Holin of 3TMs, for gene-transfer release	-	-	-	-	-	-	-	-	-	-	-	-	GTA_holin_3TM
k141_3877_5	1348635.BBJY01000007_gene158	7.19e-113	327.0	2AHM8@1|root,317Z4@2|Bacteria,1PZHN@1224|Proteobacteria,1TJ85@1236|Gammaproteobacteria,1Y0SJ@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_3877_6	1348635.BBJY01000007_gene157	1.95e-88	262.0	2AKZ1@1|root,31BSP@2|Bacteria,1Q7QA@1224|Proteobacteria,1TJ9E@1236|Gammaproteobacteria,1Y0UT@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_3877_7	1348635.BBJY01000007_gene156	1.76e-98	289.0	28WF4@1|root,32FUW@2|Bacteria,1Q0R5@1224|Proteobacteria,1TJAA@1236|Gammaproteobacteria,1Y0W7@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_3877_8	1348635.BBJY01000007_gene155	2.35e-65	206.0	COG4540@1|root,COG4540@2|Bacteria,1PUM5@1224|Proteobacteria,1TASW@1236|Gammaproteobacteria,1XX7J@135623|Vibrionales	135623|Vibrionales	S	Type VI secretion system, phage-baseplate injector	-	-	-	-	-	-	-	-	-	-	-	-	Phage_base_V
k141_3877_9	301.JNHE01000016_gene4507	6.94e-29	106.0	COG4104@1|root,COG4104@2|Bacteria,1MUE3@1224|Proteobacteria,1S0E8@1236|Gammaproteobacteria,1YH90@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	S	PAAR motif	-	-	-	-	-	-	-	-	-	-	-	-	ART,GH-E,Ntox46,PAAR_motif
k141_2820_1	1167006.UWK_00776	1.89e-77	236.0	COG3448@1|root,COG3448@2|Bacteria,1MXJG@1224|Proteobacteria,42RSQ@68525|delta/epsilon subdivisions,2WNED@28221|Deltaproteobacteria,2MJRX@213118|Desulfobacterales	28221|Deltaproteobacteria	T	PFAM HPP family	-	-	-	ko:K07168	-	-	-	-	ko00000	-	-	-	HPP
k141_2820_2	879212.DespoDRAFT_00502	2.12e-17	75.9	COG1917@1|root,COG1917@2|Bacteria,1RJPB@1224|Proteobacteria,42T5Q@68525|delta/epsilon subdivisions,2WPWB@28221|Deltaproteobacteria,2MNKI@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_3203_1	339860.Msp_0037	0.00024	43.1	COG4992@1|root,arCOG00914@2157|Archaea,2XTKV@28890|Euryarchaeota,23NTA@183925|Methanobacteria	183925|Methanobacteria	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily	argD	-	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
k141_3203_2	768710.DesyoDRAFT_3560	2.02e-06	50.8	COG1618@1|root,COG1618@2|Bacteria,1VGU5@1239|Firmicutes,24QRA@186801|Clostridia,2657V@186807|Peptococcaceae	186801|Clostridia	F	nucleotide kinase	-	-	3.6.1.15	ko:K06928	ko00230,ko00730,ko01100,map00230,map00730,map01100	-	R00086,R00615	RC00002	ko00000,ko00001,ko01000	-	-	-	NTPase_1
k141_1871_1	323850.Shew_0492	1.77e-44	160.0	COG0840@1|root,COG2703@1|root,COG0840@2|Bacteria,COG2703@2|Bacteria,1RBB1@1224|Proteobacteria,1S265@1236|Gammaproteobacteria,2Q9DW@267890|Shewanellaceae	1236|Gammaproteobacteria	NPT	Hemerythrin HHE cation binding domain protein	-	-	-	ko:K07216	-	-	-	-	ko00000	-	-	-	Hemerythrin,MCPsignal
k141_2473_1	945543.VIBR0546_21230	2.92e-153	438.0	COG4168@1|root,COG4168@2|Bacteria,1QUAU@1224|Proteobacteria,1T1RR@1236|Gammaproteobacteria,1XTN1@135623|Vibrionales	135623|Vibrionales	P	peptide transport system, permease	sapB	-	-	ko:K19227	ko01503,ko02010,map01503,map02010	M00739	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.5	-	-	BPD_transp_1
k141_3878_1	180332.JTGN01000004_gene2396	1.41e-31	121.0	COG4976@1|root,COG4976@2|Bacteria,1UHZM@1239|Firmicutes,24A6U@186801|Clostridia	186801|Clostridia	S	Methyltransferase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
k141_1872_1	382245.ASA_2935	1.06e-69	223.0	COG2801@1|root,COG2963@1|root,COG2801@2|Bacteria,COG2963@2|Bacteria,1MVXQ@1224|Proteobacteria,1RPEW@1236|Gammaproteobacteria,1Y6KM@135624|Aeromonadales	135624|Aeromonadales	L	HTH-like domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_21,HTH_Tnp_1,rve
k141_220_2	357804.Ping_3453	1.29e-78	252.0	COG4987@1|root,COG4987@2|Bacteria,1QU1P@1224|Proteobacteria,1RQD7@1236|Gammaproteobacteria,2QIIE@267894|Psychromonadaceae	1236|Gammaproteobacteria	V	ABC transporter transmembrane region	cydC	GO:0000101,GO:0003333,GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006857,GO:0006865,GO:0008150,GO:0009889,GO:0015399,GO:0015405,GO:0015711,GO:0015804,GO:0015833,GO:0015849,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019222,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0031323,GO:0031326,GO:0032973,GO:0032991,GO:0033228,GO:0034220,GO:0034635,GO:0034775,GO:0035443,GO:0035672,GO:0042623,GO:0042626,GO:0042883,GO:0042886,GO:0042939,GO:0043190,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0050789,GO:0050794,GO:0051171,GO:0051179,GO:0051181,GO:0051193,GO:0051234,GO:0055085,GO:0065007,GO:0070453,GO:0071702,GO:0071705,GO:0071944,GO:0072337,GO:0072348,GO:0098533,GO:0098655,GO:0098656,GO:0098796,GO:0098797,GO:0140115,GO:1901401,GO:1901463,GO:1902494,GO:1902495,GO:1903712,GO:1903825,GO:1904949,GO:1905039,GO:1990351	-	ko:K16012	ko02010,map02010	-	-	-	ko00000,ko00001,ko02000	3.A.1.129	-	iEC55989_1330.EC55989_0931,iECIAI1_1343.ECIAI1_0926,iECO103_1326.ECO103_0929,iECO111_1330.ECO111_0954,iECSE_1348.ECSE_0944,iECW_1372.ECW_m0996,iEKO11_1354.EKO11_2951,iSDY_1059.SDY_2375,iWFL_1372.ECW_m0996	ABC_membrane,ABC_tran
k141_2171_4	223926.28806577	2.59e-34	119.0	2EIY9@1|root,33CPF@2|Bacteria,1NNY6@1224|Proteobacteria,1SHUV@1236|Gammaproteobacteria,1XYDZ@135623|Vibrionales	135623|Vibrionales	-	-	VP1586	-	-	-	-	-	-	-	-	-	-	-	HTH_3
k141_2171_7	1123367.C666_12635	1.03e-40	153.0	COG4128@1|root,COG4128@2|Bacteria,1REHG@1224|Proteobacteria,2VRK2@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Zonular occludens toxin (Zot)	-	-	-	-	-	-	-	-	-	-	-	-	Zot
k141_1873_1	1304885.AUEY01000082_gene2153	3.17e-114	342.0	COG1902@1|root,COG1902@2|Bacteria,1MVE0@1224|Proteobacteria,42NA7@68525|delta/epsilon subdivisions,2WIN5@28221|Deltaproteobacteria,2MJ30@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM NADH flavin oxidoreductase NADH oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_FMN
k141_1873_2	1265503.KB905161_gene3262	5e-22	95.5	COG1309@1|root,COG1309@2|Bacteria,1RA4T@1224|Proteobacteria,1RNQH@1236|Gammaproteobacteria,2Q7N9@267889|Colwelliaceae	1236|Gammaproteobacteria	K	Bacterial transcriptional repressor C-terminal	-	-	-	ko:K16137	-	-	-	-	ko00000,ko03000	-	-	-	TetR_C_13,TetR_N
k141_1210_1	675813.VIB_001975	4.49e-89	284.0	COG3107@1|root,COG3107@2|Bacteria,1MUHR@1224|Proteobacteria,1RXX4@1236|Gammaproteobacteria,1XT66@135623|Vibrionales	135623|Vibrionales	M	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a)	lpoA	-	-	ko:K07121	-	-	-	-	ko00000	-	-	-	LppC
k141_1210_2	1191299.AJYX01000052_gene1441	2.48e-165	467.0	COG0313@1|root,COG0313@2|Bacteria,1MU0E@1224|Proteobacteria,1RM7U@1236|Gammaproteobacteria,1XU78@135623|Vibrionales	135623|Vibrionales	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA	rsmI	GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
k141_2476_1	526222.Desal_2097	2.21e-114	332.0	COG0108@1|root,COG0108@2|Bacteria,1MU8P@1224|Proteobacteria,42PMN@68525|delta/epsilon subdivisions,2WJJ0@28221|Deltaproteobacteria,2M89V@213115|Desulfovibrionales	28221|Deltaproteobacteria	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	ribB	-	4.1.99.12	ko:K02858	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R07281	RC01792,RC01815	ko00000,ko00001,ko00002,ko01000	-	-	-	DHBP_synthase
k141_222_1	1304885.AUEY01000024_gene2727	3.65e-152	451.0	COG0303@1|root,COG1910@1|root,COG0303@2|Bacteria,COG1910@2|Bacteria,1MVD5@1224|Proteobacteria,42NQY@68525|delta/epsilon subdivisions,2WISG@28221|Deltaproteobacteria,2MIXC@213118|Desulfobacterales	28221|Deltaproteobacteria	HP	MoeA domain protein domain I and II	-	-	2.10.1.1	ko:K03750,ko:K07219	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N,PBP_like
k141_222_2	339860.Msp_0014	1.73e-48	167.0	COG1968@1|root,arCOG04761@2157|Archaea,2XTYX@28890|Euryarchaeota,23NY7@183925|Methanobacteria	183925|Methanobacteria	I	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP)	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
k141_4202_2	298386.PBPRA0467	1.17e-238	669.0	COG1070@1|root,COG1070@2|Bacteria,1MW4A@1224|Proteobacteria,1RR7X@1236|Gammaproteobacteria,1XUAS@135623|Vibrionales	135623|Vibrionales	G	Xylulose kinase	xylB	-	2.7.1.17	ko:K00854	ko00040,ko01100,map00040,map01100	M00014	R01639	RC00002,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	-	FGGY_C,FGGY_N
k141_4202_3	1278307.KB906982_gene4004	6.01e-202	568.0	COG1609@1|root,COG2207@1|root,COG1609@2|Bacteria,COG2207@2|Bacteria,1NYTD@1224|Proteobacteria,1RNGZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	transcriptional regulator	xylR	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	HTH_18,HTH_AraC,Peripla_BP_3
k141_4202_4	314292.VAS14_11089	3.77e-241	673.0	COG0477@1|root,COG0477@2|Bacteria,1NS3F@1224|Proteobacteria,1T1MQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	EGP	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family	xylE	-	-	ko:K08138,ko:K08139	ko04113,map04113	-	-	-	ko00000,ko00001,ko02000	2.A.1.1,2.A.1.1.3	-	-	Sugar_tr
k141_225_1	520999.PROVALCAL_02343	1.28e-86	270.0	COG0579@1|root,COG0579@2|Bacteria,1N0QB@1224|Proteobacteria,1RN24@1236|Gammaproteobacteria,3Z7B2@586|Providencia	1236|Gammaproteobacteria	S	FAD dependent oxidoreductase	-	-	1.1.5.3	ko:K00111	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	DAO,Fer2_BFD
k141_3879_1	706587.Desti_5487	1.52e-182	523.0	COG2710@1|root,COG2710@2|Bacteria,1MVY2@1224|Proteobacteria,42MMI@68525|delta/epsilon subdivisions,2WJZI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Nitrogenase molybdenum-iron protein alpha chain	nifD	-	1.18.6.1	ko:K02586	ko00625,ko00910,ko01100,ko01120,map00625,map00910,map01100,map01120	M00175	R05185,R05496	RC00002,RC01395,RC02891	ko00000,ko00001,ko00002,ko01000	-	-	-	Oxidored_nitro
k141_3879_2	555779.Dthio_PD2920	3.85e-220	620.0	COG2710@1|root,COG2710@2|Bacteria,1MWQ4@1224|Proteobacteria,42MNG@68525|delta/epsilon subdivisions,2WIWX@28221|Deltaproteobacteria,2M8N7@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation	nifK	-	1.18.6.1	ko:K02591	ko00625,ko00910,ko01100,ko01120,map00625,map00910,map01100,map01120	M00175	R05185,R05496	RC00002,RC01395,RC02891	ko00000,ko00001,ko00002,ko01000	-	-	-	Oxidored_nitro
k141_3879_3	1121459.AQXE01000007_gene708	1.29e-32	117.0	COG3411@1|root,COG3411@2|Bacteria,1RM68@1224|Proteobacteria,42TUK@68525|delta/epsilon subdivisions,2WQGU@28221|Deltaproteobacteria,2MGMY@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	Ferredoxin	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_3879_4	526222.Desal_0439	8.06e-131	383.0	COG2710@1|root,COG2710@2|Bacteria,1MWAJ@1224|Proteobacteria,42M5T@68525|delta/epsilon subdivisions,2WJF2@28221|Deltaproteobacteria,2M9IM@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	Belongs to the NifD NifK NifE NifN family	nifE	-	-	ko:K02587	-	-	-	-	ko00000	-	-	-	Oxidored_nitro
k141_3204_2	56107.Cylst_2590	2.18e-37	157.0	COG1572@1|root,COG3103@1|root,COG1572@2|Bacteria,COG3103@2|Bacteria,1G1E0@1117|Cyanobacteria,1HQ7D@1161|Nostocales	1117|Cyanobacteria	T	Calpain family cysteine protease	-	-	-	-	-	-	-	-	-	-	-	-	DUF4114,PPC,Peptidase_C2
k141_3204_3	1121403.AUCV01000017_gene4522	8.01e-22	101.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42MXI@68525|delta/epsilon subdivisions,2WIX9@28221|Deltaproteobacteria,2MHVJ@213118|Desulfobacterales	28221|Deltaproteobacteria	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,Cache_3-Cache_2,HAMP,MCPsignal,PAS_3,dCache_1,sCache_2
k141_2172_1	439235.Dalk_1439	2.35e-188	542.0	COG0147@1|root,COG0147@2|Bacteria,1MVBJ@1224|Proteobacteria,42MXN@68525|delta/epsilon subdivisions,2WJN0@28221|Deltaproteobacteria,2MI03@213118|Desulfobacterales	28221|Deltaproteobacteria	EH	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia	trpE	-	4.1.3.27	ko:K01657,ko:K13503	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
k141_2172_2	56780.SYN_01946	1.11e-66	209.0	COG0512@1|root,COG0512@2|Bacteria,1MV5Y@1224|Proteobacteria,42QTS@68525|delta/epsilon subdivisions,2WN02@28221|Deltaproteobacteria,2MQC6@213462|Syntrophobacterales	28221|Deltaproteobacteria	EH	TIGRFAM glutamine amidotransferase of anthranilate synthase	trpG	-	2.6.1.85,4.1.3.27	ko:K01658,ko:K01664	ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986,R01716	RC00010,RC01418,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2496	GATase
k141_226_1	55601.VANGNB10_cI0439	1.25e-90	275.0	COG1388@1|root,COG4942@1|root,COG1388@2|Bacteria,COG4942@2|Bacteria,1RD24@1224|Proteobacteria,1RR11@1236|Gammaproteobacteria,1XSDC@135623|Vibrionales	135623|Vibrionales	M	COG0739 Membrane proteins related to metalloendopeptidases	nlpD	-	-	ko:K06194	-	-	-	-	ko00000	1.A.34.1.2	-	-	LysM,Peptidase_M23
k141_1875_1	177437.HRM2_01970	1.24e-105	326.0	COG0446@1|root,COG1902@1|root,COG0446@2|Bacteria,COG1902@2|Bacteria,1MVE0@1224|Proteobacteria,42PDA@68525|delta/epsilon subdivisions,2WK05@28221|Deltaproteobacteria,2MHS3@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM NADH flavin oxidoreductase NADH oxidase	-	-	1.3.1.34	ko:K00219	-	-	-	-	ko00000,ko01000	-	-	-	Oxidored_FMN,Pyr_redox_2
k141_1875_2	1304885.AUEY01000012_gene1791	3.7e-102	306.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,42MK5@68525|delta/epsilon subdivisions,2WJ3Z@28221|Deltaproteobacteria,2MI0N@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM Acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
k141_2173_1	391596.PBAL39_15199	2.03e-20	93.6	COG0745@1|root,COG3829@1|root,COG0745@2|Bacteria,COG3829@2|Bacteria	2|Bacteria	T	transcription factor binding	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,HisKA_3,PAS,PAS_3,PAS_4,PAS_9,Response_reg
k141_3880_1	1034809.SLUG_23500	9e-131	397.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4H9ZY@91061|Bacilli,4GXQ4@90964|Staphylococcaceae	91061|Bacilli	V	ABC transporter transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
k141_2478_2	177437.HRM2_22130	2.52e-185	530.0	COG0205@1|root,COG0205@2|Bacteria,1MVN3@1224|Proteobacteria,42NMZ@68525|delta/epsilon subdivisions,2WIZ0@28221|Deltaproteobacteria,2MINS@213118|Desulfobacterales	28221|Deltaproteobacteria	G	Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Atypical ATP- dependent clade X sub-subfamily	pfkA	-	2.7.1.11	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	M00001,M00345	R00756,R03236,R03237,R03238,R03239,R04779	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	-	-	-	PFK
k141_2478_3	933262.AXAM01000004_gene2399	7.17e-19	85.5	COG0517@1|root,COG0794@1|root,COG0517@2|Bacteria,COG0794@2|Bacteria,1MUXD@1224|Proteobacteria,42M0M@68525|delta/epsilon subdivisions,2WJ4Y@28221|Deltaproteobacteria,2MIJI@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Belongs to the SIS family. GutQ KpsF subfamily	kpsF	-	5.3.1.13	ko:K06041	ko00540,ko01100,map00540,map01100	M00063	R01530	RC00541	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CBS,SIS
k141_2175_1	1121373.KB903621_gene1862	2.15e-20	90.9	COG3852@1|root,COG3852@2|Bacteria,4P3WV@976|Bacteroidetes	976|Bacteroidetes	T	PAS fold	-	-	-	-	-	-	-	-	-	-	-	-	PAS_4
k141_228_1	345073.VC395_2087	9.33e-105	313.0	COG1441@1|root,COG1441@2|Bacteria,1MV33@1224|Proteobacteria,1RRC0@1236|Gammaproteobacteria,1XTPS@135623|Vibrionales	135623|Vibrionales	H	Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)	menC	GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663	4.2.1.113	ko:K02549	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R04031	RC01053	ko00000,ko00001,ko00002,ko01000	-	-	-	MR_MLE_C
k141_2479_1	879212.DespoDRAFT_02322	2.06e-09	59.7	COG0642@1|root,COG2205@2|Bacteria,1R1WY@1224|Proteobacteria,43DC0@68525|delta/epsilon subdivisions,2X8I1@28221|Deltaproteobacteria,2MPNY@213118|Desulfobacterales	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_2479_2	1265505.ATUG01000001_gene2864	6.48e-25	96.3	COG0745@1|root,COG0745@2|Bacteria,1MZGI@1224|Proteobacteria,42UM3@68525|delta/epsilon subdivisions,2WR2K@28221|Deltaproteobacteria,2MNP6@213118|Desulfobacterales	28221|Deltaproteobacteria	KT	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
k141_4205_1	1237149.C900_03005	1.1e-54	204.0	COG3422@1|root,COG3422@2|Bacteria,4NHE4@976|Bacteroidetes,47NKA@768503|Cytophagia	976|Bacteroidetes	H	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_4205_2	338966.Ppro_0365	6.63e-45	154.0	2BXP3@1|root,2ZA5J@2|Bacteria,1R484@1224|Proteobacteria,430RZ@68525|delta/epsilon subdivisions,2WVU5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_2176_1	335543.Sfum_2600	1.98e-57	191.0	COG3547@1|root,COG3547@2|Bacteria,1NGR7@1224|Proteobacteria,42NNQ@68525|delta/epsilon subdivisions,2WM2H@28221|Deltaproteobacteria,2MSJJ@213462|Syntrophobacterales	28221|Deltaproteobacteria	L	PFAM transposase IS116 IS110 IS902 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k141_2485_35	1238450.VIBNISOn1_1610072	2.21e-24	92.8	2EG1V@1|root,339TV@2|Bacteria,1NI0B@1224|Proteobacteria,1SGIA@1236|Gammaproteobacteria,1XZ4Y@135623|Vibrionales	135623|Vibrionales	S	Domain of unknown function (DUF4250)	BT4646	-	-	-	-	-	-	-	-	-	-	-	DUF4250
k141_3907_1	314282.PCNPT3_12170	1.26e-19	90.5	COG2246@1|root,COG2246@2|Bacteria	2|Bacteria	S	polysaccharide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	GtrA
k141_3907_2	1188252.AJYK01000094_gene1577	9.73e-33	128.0	COG2246@1|root,COG2246@2|Bacteria,1R2TS@1224|Proteobacteria,1T5XD@1236|Gammaproteobacteria,1XTY2@135623|Vibrionales	135623|Vibrionales	S	GtrA-like protein	-	-	-	-	-	-	-	-	-	-	-	-	GtrA
k141_3907_3	1219080.VEZ01S_37_00640	2.07e-179	505.0	COG0463@1|root,COG0463@2|Bacteria,1MWE5@1224|Proteobacteria,1RPCE@1236|Gammaproteobacteria,1XSFK@135623|Vibrionales	135623|Vibrionales	M	COG0463 Glycosyltransferases involved in cell wall biogenesis	-	-	-	ko:K20534	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.2.1.9	GT2	-	Glycos_transf_2
k141_3562_1	1282361.ABAC402_08205	1.43e-50	186.0	COG0574@1|root,COG3848@1|root,COG0574@2|Bacteria,COG3848@2|Bacteria,1Q33X@1224|Proteobacteria,2TV1E@28211|Alphaproteobacteria	28211|Alphaproteobacteria	GPU	Pyruvate phosphate dikinase, PEP/pyruvate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	60KD_IMP,PEP-utilizers,PPDK_N,Rhodanese
k141_4614_1	1390370.O203_04210	1.79e-31	130.0	COG2931@1|root,COG2982@1|root,COG3210@1|root,COG4625@1|root,COG2931@2|Bacteria,COG2982@2|Bacteria,COG3210@2|Bacteria,COG4625@2|Bacteria,1MU7T@1224|Proteobacteria,1S1HJ@1236|Gammaproteobacteria,1YFJH@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	MQU	Domain of unknown function (DUF4347)	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin,Cadherin_3,DUF4214,DUF4347,He_PIG,HemolysinCabind,PATR,VCBS
k141_5197_2	675815.VOA_000261	3.33e-47	159.0	COG0551@1|root,COG0551@2|Bacteria,1RJ5B@1224|Proteobacteria,1S349@1236|Gammaproteobacteria,1XT3J@135623|Vibrionales	135623|Vibrionales	L	Zn-finger domain associated with topoisomerase type I	-	-	-	-	-	-	-	-	-	-	-	-	DUF2726
k141_253_4	675813.VIB_002468	4.88e-231	638.0	COG1063@1|root,COG1063@2|Bacteria,1MV9A@1224|Proteobacteria,1RMNY@1236|Gammaproteobacteria,1XUZV@135623|Vibrionales	135623|Vibrionales	C	Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate	tdh	GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006566,GO:0006567,GO:0006807,GO:0008150,GO:0008152,GO:0008743,GO:0009056,GO:0009063,GO:0009066,GO:0009068,GO:0009987,GO:0016054,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0055114,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	1.1.1.103	ko:K00060	ko00260,map00260	-	R01465	RC00525	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
k141_253_5	243277.VC_A0886	5.17e-243	672.0	COG0156@1|root,COG0156@2|Bacteria,1MVVH@1224|Proteobacteria,1RNS6@1236|Gammaproteobacteria,1XSBG@135623|Vibrionales	135623|Vibrionales	H	Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA	kbl	-	2.3.1.29	ko:K00639	ko00260,map00260	-	R00371	RC00004,RC00394	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
k141_253_6	675815.VOA_000960	4.01e-150	430.0	COG0583@1|root,COG0583@2|Bacteria,1N4BZ@1224|Proteobacteria,1RRCD@1236|Gammaproteobacteria,1XTHR@135623|Vibrionales	135623|Vibrionales	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
k141_253_7	32042.PstZobell_11309	1.16e-65	202.0	COG0346@1|root,COG0346@2|Bacteria,1RGZ8@1224|Proteobacteria,1S66M@1236|Gammaproteobacteria,1Z2WJ@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	E	Glyoxylase I family protein	yaeR	-	-	ko:K08234	-	-	-	-	ko00000	-	-	-	Glyoxalase
k141_253_8	55601.VANGNB10_cII0811c	2.46e-126	365.0	COG1387@1|root,COG1387@2|Bacteria,1MYXV@1224|Proteobacteria,1RRE9@1236|Gammaproteobacteria,1XTMG@135623|Vibrionales	135623|Vibrionales	E	Histidinol phosphatase and related hydrolases of the PHP family	-	GO:0001539,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006928,GO:0008150,GO:0008270,GO:0009987,GO:0016787,GO:0016788,GO:0040011,GO:0042578,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0048870,GO:0051179,GO:0051674,GO:0071973,GO:0071978,GO:0097588	-	ko:K04477	-	-	-	-	ko00000	-	-	-	PHP
k141_3563_1	575788.VS_II0135	2.55e-49	159.0	2AXBQ@1|root,31PAV@2|Bacteria,1QM13@1224|Proteobacteria,1TJ80@1236|Gammaproteobacteria,1Y0SA@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_786_1	1123514.KB905903_gene425	2.48e-27	99.8	2DP8N@1|root,3311E@2|Bacteria,1NC4X@1224|Proteobacteria,1SECM@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_786_2	345073.VC395_0434	0.0	2036.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,1MV6G@1224|Proteobacteria,1RMYD@1236|Gammaproteobacteria,1XSUY@135623|Vibrionales	135623|Vibrionales	E	COG0646 Methionine synthase I (cobalamin-dependent), methyltransferase domain	metH	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0019752,GO:0032259,GO:0042084,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
k141_786_3	672.VV93_v1c26810	2.92e-242	677.0	COG0527@1|root,COG0527@2|Bacteria,1MW3H@1224|Proteobacteria,1RMJ6@1236|Gammaproteobacteria,1XSHB@135623|Vibrionales	135623|Vibrionales	E	Belongs to the aspartokinase family	lysC	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
k141_2029_4	1499967.BAYZ01000036_gene2437	3.41e-141	410.0	COG0330@1|root,COG0330@2|Bacteria,2NP3W@2323|unclassified Bacteria	2|Bacteria	O	HflC and HflK could encode or regulate a protease	hflK	-	-	ko:K04088	-	M00742	-	-	ko00000,ko00002,ko01000	-	-	-	Band_7
k141_2029_5	1121403.AUCV01000056_gene3022	4.65e-160	457.0	COG0330@1|root,COG0330@2|Bacteria,1MV7R@1224|Proteobacteria,42N2V@68525|delta/epsilon subdivisions,2WIPS@28221|Deltaproteobacteria,2MIPC@213118|Desulfobacterales	28221|Deltaproteobacteria	O	HflC and HflK could regulate a protease	hflC	-	-	ko:K04087	-	M00742	-	-	ko00000,ko00002,ko01000	-	-	-	Band_7
k141_2029_7	96561.Dole_2313	1.41e-226	639.0	COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,42MEA@68525|delta/epsilon subdivisions,2WIW6@28221|Deltaproteobacteria,2MI74@213118|Desulfobacterales	28221|Deltaproteobacteria	KT	Sigma-54 interaction domain	-	-	2.1.1.80	ko:K00575	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	HTH_8,PAS_4,PAS_9,Sigma54_activat
k141_5019_1	497964.CfE428DRAFT_2310	9.44e-20	95.1	COG2204@1|root,COG2204@2|Bacteria,46U7R@74201|Verrucomicrobia	74201|Verrucomicrobia	T	Sigma-54 interaction domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Sigma54_activat
k141_4750_1	1232437.KL662077_gene1941	4.54e-258	716.0	COG0471@1|root,COG0471@2|Bacteria,1MUSA@1224|Proteobacteria,43BQX@68525|delta/epsilon subdivisions,2X71W@28221|Deltaproteobacteria,2MIFV@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Sodium:sulfate symporter transmembrane region	-	-	-	ko:K14445	-	-	-	-	ko00000,ko02000	2.A.47.1	-	-	Na_sulph_symp
k141_2936_1	345073.VC395_2816	4.87e-243	684.0	COG3263@1|root,COG3263@2|Bacteria,1MVKV@1224|Proteobacteria,1RMCA@1236|Gammaproteobacteria,1XTCU@135623|Vibrionales	135623|Vibrionales	P	K( ) H( ) antiporter that extrudes potassium in exchange for external protons and maintains the internal concentration of potassium under toxic levels	nhaP2	-	-	ko:K11105	-	-	-	-	ko00000,ko02000	2.A.36.6	-	-	CorC_HlyC,Na_H_Exchanger,TrkA_C
k141_1581_1	675814.VIC_003391	3.32e-105	313.0	COG2207@1|root,COG3449@1|root,COG2207@2|Bacteria,COG3449@2|Bacteria,1MWTF@1224|Proteobacteria,1RMKE@1236|Gammaproteobacteria,1XT8F@135623|Vibrionales	135623|Vibrionales	K	Bacterial transcription activator, effector binding domain	-	-	-	ko:K13652	-	-	-	-	ko00000,ko03000	-	-	-	GyrI-like,HTH_18
k141_1581_3	1348635.BBJY01000014_gene799	3.14e-43	145.0	2E4HY@1|root,33HKA@2|Bacteria,1NIGQ@1224|Proteobacteria,1SHKJ@1236|Gammaproteobacteria,1XXT7@135623|Vibrionales	135623|Vibrionales	S	Late competence development protein ComFB	-	-	-	-	-	-	-	-	-	-	-	-	ComFB
k141_1581_4	1001530.BACE01000027_gene806	8.9e-31	111.0	COG5453@1|root,COG5453@2|Bacteria,1N7WA@1224|Proteobacteria,1SGQT@1236|Gammaproteobacteria,1XYAD@135623|Vibrionales	135623|Vibrionales	S	Transcriptional activator HlyU	R01627	-	-	-	-	-	-	-	-	-	-	-	HlyU
k141_1581_7	1219065.VPR01S_07_00970	6.45e-44	156.0	COG0642@1|root,COG0642@2|Bacteria,1R9IX@1224|Proteobacteria,1SMI3@1236|Gammaproteobacteria,1XTIK@135623|Vibrionales	135623|Vibrionales	T	COG0642 Signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	DUF3404,HATPase_c,HisKA
k141_2030_1	439235.Dalk_1103	1.67e-25	104.0	COG0422@1|root,COG0422@2|Bacteria,1MUVV@1224|Proteobacteria,42MMB@68525|delta/epsilon subdivisions,2WJEI@28221|Deltaproteobacteria,2MIFI@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction	thiC	-	4.1.99.17	ko:K03147	ko00730,ko01100,map00730,map01100	M00127	R03472	RC03251,RC03252	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2910	ThiC_Rad_SAM
k141_2030_2	485915.Dret_0893	1.13e-108	329.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,42MMK@68525|delta/epsilon subdivisions,2WJC1@28221|Deltaproteobacteria,2M8SI@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	PFAM ABC transporter related	yjjK	-	3.6.3.25	ko:K06020	-	-	-	-	ko00000,ko01000	-	-	-	ABC_tran,ABC_tran_Xtn
k141_4752_1	1304885.AUEY01000002_gene380	2.75e-25	101.0	COG3168@1|root,COG3168@2|Bacteria,1N39F@1224|Proteobacteria,42U30@68525|delta/epsilon subdivisions,2WRT8@28221|Deltaproteobacteria,2MPRF@213118|Desulfobacterales	28221|Deltaproteobacteria	NU	Pilus assembly protein, PilP	-	-	-	ko:K02665	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilP
k141_2620_2	1042375.AFPL01000031_gene798	6.36e-99	318.0	COG0226@1|root,COG2885@1|root,COG0226@2|Bacteria,COG2885@2|Bacteria,1MVXP@1224|Proteobacteria,1RNK7@1236|Gammaproteobacteria,46D11@72275|Alteromonadaceae	1236|Gammaproteobacteria	MP	PBP superfamily domain	-	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	OmpA,PBP_like_2
k141_3287_1	945550.VISI1226_11142	7.05e-191	553.0	COG0460@1|root,COG0527@1|root,COG0460@2|Bacteria,COG0527@2|Bacteria,1MW3H@1224|Proteobacteria,1RN1G@1236|Gammaproteobacteria,1XSVP@135623|Vibrionales	135623|Vibrionales	E	Bifunctional aspartate kinase II homoserine dehydrogenase II	metL	-	1.1.1.3,2.7.2.4	ko:K12525	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00017,M00018,M00526,M00527	R00480,R01773,R01775	RC00002,RC00043,RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,Homoserine_dh,NAD_binding_3
k141_3287_3	1191299.AJYX01000051_gene1259	2.65e-28	103.0	COG3074@1|root,COG3074@2|Bacteria,1MZJE@1224|Proteobacteria,1S8TG@1236|Gammaproteobacteria,1XYCG@135623|Vibrionales	135623|Vibrionales	D	Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA	zapB	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K09892	-	-	-	-	ko00000,ko03036	-	-	-	ZapB
k141_670_1	1121396.KB893085_gene343	1.43e-53	191.0	COG1020@1|root,COG1020@2|Bacteria,1QK4F@1224|Proteobacteria,42Z5Y@68525|delta/epsilon subdivisions,2X8JI@28221|Deltaproteobacteria,2MMZD@213118|Desulfobacterales	1224|Proteobacteria	Q	Condensation domain	-	-	-	ko:K04786	ko01053,map01053	-	-	-	ko00000,ko00001,ko01004,ko01008	-	-	-	AMP-binding,AMP-binding_C,Acyl_transf_1,Condensation,KAsynt_C_assoc,KR,Ketoacyl-synt_C,Methyltransf_12,PP-binding,PS-DH,ketoacyl-synt
k141_670_2	1121403.AUCV01000045_gene1165	8.6e-08	54.3	COG1629@1|root,COG4771@2|Bacteria,1MWKN@1224|Proteobacteria,42MNM@68525|delta/epsilon subdivisions,2WMEW@28221|Deltaproteobacteria,2MMGV@213118|Desulfobacterales	28221|Deltaproteobacteria	P	TonB dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
k141_4347_1	1121396.KB892957_gene3229	2.66e-79	246.0	COG0136@1|root,COG0136@2|Bacteria,1MUHG@1224|Proteobacteria,42MDM@68525|delta/epsilon subdivisions,2WJ5Y@28221|Deltaproteobacteria,2MI40@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate	asd	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
k141_5296_1	96561.Dole_1925	3.97e-113	333.0	COG0226@1|root,COG0226@2|Bacteria,1MVXP@1224|Proteobacteria,42P0G@68525|delta/epsilon subdivisions,2WK7Y@28221|Deltaproteobacteria,2MJ1S@213118|Desulfobacterales	28221|Deltaproteobacteria	P	TIGRFAM phosphate binding protein	-	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
k141_5296_2	1304885.AUEY01000038_gene2564	1.11e-130	380.0	COG0573@1|root,COG0573@2|Bacteria,1MVKP@1224|Proteobacteria,42N2N@68525|delta/epsilon subdivisions,2WJJ1@28221|Deltaproteobacteria,2MHPU@213118|Desulfobacterales	28221|Deltaproteobacteria	P	probably responsible for the translocation of the substrate across the membrane	pstC	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
k141_5296_3	1232437.KL661969_gene4933	2.09e-135	391.0	COG0581@1|root,COG0581@2|Bacteria,1MUWB@1224|Proteobacteria,42MWK@68525|delta/epsilon subdivisions,2WJKH@28221|Deltaproteobacteria,2MJ3A@213118|Desulfobacterales	28221|Deltaproteobacteria	P	TIGRFAM phosphate ABC transporter, inner membrane subunit PstA	pstA	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
k141_5296_4	207559.Dde_2386	2.67e-141	403.0	COG1117@1|root,COG1117@2|Bacteria,1MU16@1224|Proteobacteria,42MWA@68525|delta/epsilon subdivisions,2WJEX@28221|Deltaproteobacteria,2M7VZ@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
k141_5296_5	96561.Dole_1929	1.25e-68	216.0	COG0704@1|root,COG0704@2|Bacteria,1MUMI@1224|Proteobacteria,42QWG@68525|delta/epsilon subdivisions,2WN1U@28221|Deltaproteobacteria,2MICR@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Plays a role in the regulation of phosphate uptake	phoU	-	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
k141_5296_6	1304885.AUEY01000038_gene2560	1.68e-96	288.0	COG0745@1|root,COG0745@2|Bacteria,1MY2Z@1224|Proteobacteria,42MP1@68525|delta/epsilon subdivisions,2WJPD@28221|Deltaproteobacteria,2MJ7C@213118|Desulfobacterales	28221|Deltaproteobacteria	T	PFAM response regulator receiver	-	-	-	ko:K07657	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
k141_5296_7	1121405.dsmv_0047	1.21e-148	449.0	COG5002@1|root,COG5002@2|Bacteria,1MWF3@1224|Proteobacteria,42NB5@68525|delta/epsilon subdivisions,2WJGX@28221|Deltaproteobacteria,2MI1J@213118|Desulfobacterales	28221|Deltaproteobacteria	T	histidine kinase HAMP region domain protein	phoR	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_8,sCache_like
k141_672_3	1122164.JHWF01000014_gene1786	1.98e-45	171.0	COG2202@1|root,COG5001@1|root,COG2202@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1JC9W@118969|Legionellales	118969|Legionellales	T	Putative diguanylate phosphodiesterase	-	-	3.1.4.52	ko:K21024	ko02025,map02025	-	-	-	ko00000,ko00001,ko01000	-	-	-	EAL,GGDEF,PAS_8,PAS_9
k141_672_4	717774.Marme_0532	3.05e-43	160.0	COG2199@1|root,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,1RMA9@1236|Gammaproteobacteria,1XK2H@135619|Oceanospirillales	135619|Oceanospirillales	T	GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
k141_674_1	879212.DespoDRAFT_02282	5.52e-68	229.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MC4@68525|delta/epsilon subdivisions,2WIU5@28221|Deltaproteobacteria,2MPNX@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_9,Response_reg
k141_4353_1	536232.CLM_1748	1.25e-09	62.4	COG1309@1|root,COG1309@2|Bacteria,1V3XC@1239|Firmicutes,24JC2@186801|Clostridia,36JQF@31979|Clostridiaceae	186801|Clostridia	K	Transcriptional regulator TetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
k141_4353_2	1265505.ATUG01000002_gene2079	0.000568	44.7	COG0775@1|root,COG0775@2|Bacteria,1NDXU@1224|Proteobacteria,42TU4@68525|delta/epsilon subdivisions,2WQX3@28221|Deltaproteobacteria,2MK3J@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Catalyzes the hydrolysis of futalosine (FL) to dehypoxanthine futalosine (DHFL) and hypoxanthine, a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnB	-	3.2.2.26	ko:K11783	ko00130,ko01110,map00130,map01110	-	R08587	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
k141_5298_1	1500893.JQNB01000001_gene2575	1.07e-44	167.0	COG1020@1|root,COG3321@1|root,COG1020@2|Bacteria,COG3321@2|Bacteria,1QK4F@1224|Proteobacteria,1RPAG@1236|Gammaproteobacteria,1X3AB@135614|Xanthomonadales	135614|Xanthomonadales	Q	non-ribosomal peptide synthetase	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,KAsynt_C_assoc,KR,Ketoacyl-synt_C,Methyltransf_12,PP-binding,PS-DH,Thioesterase,ketoacyl-synt
k141_675_1	1265505.ATUG01000001_gene4558	6.21e-218	624.0	COG0490@1|root,COG1226@1|root,COG4651@1|root,COG0490@2|Bacteria,COG1226@2|Bacteria,COG4651@2|Bacteria,1MV34@1224|Proteobacteria,42MEM@68525|delta/epsilon subdivisions,2WK23@28221|Deltaproteobacteria,2MHVK@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family	-	-	-	ko:K03455	-	-	-	-	ko00000	2.A.37	-	-	Na_H_Exchanger,TrkA_C,TrkA_N
k141_4354_2	96561.Dole_0033	8.23e-72	228.0	COG0767@1|root,COG0767@2|Bacteria,1N2HV@1224|Proteobacteria,42UV1@68525|delta/epsilon subdivisions,2WQXM@28221|Deltaproteobacteria	28221|Deltaproteobacteria	Q	COG0767 ABC-type transport system involved in resistance to organic solvents, permease component	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
k141_677_1	754436.JCM19237_5663	2.81e-115	339.0	COG1737@1|root,COG1737@2|Bacteria,1MW2B@1224|Proteobacteria,1RNDZ@1236|Gammaproteobacteria,1XWEP@135623|Vibrionales	135623|Vibrionales	K	Helix-turn-helix domain, rpiR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_6,SIS
k141_4356_1	561231.Pecwa_0986	5.5e-15	75.9	COG3395@1|root,COG3732@1|root,COG3395@2|Bacteria,COG3732@2|Bacteria,1MY30@1224|Proteobacteria,1SZS8@1236|Gammaproteobacteria,1MQEX@122277|Pectobacterium	1236|Gammaproteobacteria	G	PFAM Sorbitol phosphotransferase protein II domain protein	-	-	2.7.1.219,2.7.1.220	ko:K22129	-	-	-	-	ko00000,ko01000	-	-	-	DUF1357_C,DUF1537,EIIBC-GUT_N
k141_4356_2	742735.HMPREF9467_04785	2.41e-170	484.0	COG1995@1|root,COG1995@2|Bacteria,1TQGT@1239|Firmicutes,24A12@186801|Clostridia,21Y96@1506553|Lachnoclostridium	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	pdxA	-	1.1.1.262,1.1.1.408,1.1.1.409	ko:K00097,ko:K22024	ko00750,ko01100,map00750,map01100	M00124	R05681,R05837,R07406	RC00089,RC00675,RC01475	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxA
k141_5299_1	1304885.AUEY01000055_gene192	1.46e-307	859.0	COG0480@1|root,COG0480@2|Bacteria,1MUCV@1224|Proteobacteria,42M4T@68525|delta/epsilon subdivisions,2WIM7@28221|Deltaproteobacteria,2MIK2@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA-2	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
k141_5299_2	96561.Dole_1616	9.71e-28	110.0	COG5401@1|root,COG5401@2|Bacteria,1NA0G@1224|Proteobacteria,42V1V@68525|delta/epsilon subdivisions,2WRCV@28221|Deltaproteobacteria,2MKUK@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Sporulation and spore germination	-	-	-	-	-	-	-	-	-	-	-	-	Germane
k141_678_1	1348635.BBJY01000001_gene2381	1.21e-29	110.0	COG4657@1|root,COG4657@2|Bacteria,1MU8X@1224|Proteobacteria,1RZY6@1236|Gammaproteobacteria,1XZTK@135623|Vibrionales	135623|Vibrionales	C	Rnf-Nqr subunit, membrane protein	-	-	-	ko:K03617	-	-	-	-	ko00000	-	-	-	Rnf-Nqr
k141_957_2	1117314.PCIT_19444	2.7e-244	696.0	COG4412@1|root,COG4412@2|Bacteria,1MWWV@1224|Proteobacteria,1RZM5@1236|Gammaproteobacteria,2Q02Y@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	M	COG1404 Subtilisin-like serine proteases	-	-	-	ko:K09607	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M6
k141_957_3	452637.Oter_0553	1.84e-161	475.0	COG3673@1|root,COG3673@2|Bacteria	2|Bacteria	M	conserved protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF2235
k141_957_5	357804.Ping_2529	0.0	1078.0	COG1501@1|root,COG1501@2|Bacteria,1MWNJ@1224|Proteobacteria,1RMJ9@1236|Gammaproteobacteria,2QIKG@267894|Psychromonadaceae	1236|Gammaproteobacteria	G	Domain of unknown function (DUF5110)	malZ	GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016758,GO:0033825,GO:0046527	2.4.1.161,3.2.1.20	ko:K01187,ko:K18820	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00028,R00801,R00802,R06087,R06088	RC00028,RC00049,RC00077	ko00000,ko00001,ko01000	-	GH31	-	CBM_20,DUF4968,DUF5110,Gal_mutarotas_2,Glyco_hydro_31
k141_957_7	983917.RGE_07010	1.34e-88	281.0	COG0154@1|root,COG0154@2|Bacteria,1MU51@1224|Proteobacteria,2VIXK@28216|Betaproteobacteria	28216|Betaproteobacteria	J	Belongs to the amidase family	-	-	3.5.1.4,6.3.5.6,6.3.5.7	ko:K01426,ko:K02433	ko00330,ko00360,ko00380,ko00627,ko00643,ko00970,ko01100,ko01120,map00330,map00360,map00380,map00627,map00643,map00970,map01100,map01120	-	R02540,R03096,R03180,R03905,R03909,R04212,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
k141_957_9	717774.Marme_3750	2.65e-62	191.0	COG2329@1|root,COG2329@2|Bacteria,1N062@1224|Proteobacteria,1SABZ@1236|Gammaproteobacteria,1XRIU@135619|Oceanospirillales	135619|Oceanospirillales	S	enzyme involved in biosynthesis of extracellular polysaccharides	-	-	-	-	-	-	-	-	-	-	-	-	ABM
k141_957_10	357804.Ping_1931	7.2e-135	392.0	2E2AN@1|root,32XG2@2|Bacteria,1N3CE@1224|Proteobacteria,1SB3R@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_957_12	1190606.AJYG01000007_gene2425	1.68e-140	409.0	28IH6@1|root,2Z8IF@2|Bacteria,1R4Z0@1224|Proteobacteria,1RS34@1236|Gammaproteobacteria,1Y111@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_957_14	1348635.BBJY01000004_gene2995	1.23e-70	218.0	2ANPA@1|root,31DNS@2|Bacteria,1RHTE@1224|Proteobacteria,1S2Z7@1236|Gammaproteobacteria,1XWZY@135623|Vibrionales	135623|Vibrionales	S	Protein of unknown function (DUF3833)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3833
k141_957_15	1187848.AJYQ01000135_gene1140	3e-80	238.0	COG0662@1|root,COG0662@2|Bacteria,1RHWU@1224|Proteobacteria,1S5VV@1236|Gammaproteobacteria,1XXU1@135623|Vibrionales	135623|Vibrionales	G	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
k141_957_16	998674.ATTE01000001_gene1273	4.6e-61	191.0	COG1846@1|root,COG1846@2|Bacteria,1NA1D@1224|Proteobacteria,1SF3N@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	MarR family	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
k141_957_17	930169.B5T_00730	2.28e-129	375.0	COG0596@1|root,COG0596@2|Bacteria,1MVTG@1224|Proteobacteria,1RQ1B@1236|Gammaproteobacteria,1XMF2@135619|Oceanospirillales	135619|Oceanospirillales	S	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
k141_957_18	1120970.AUBZ01000001_gene3688	8.64e-19	85.9	COG3326@1|root,COG3326@2|Bacteria,1N6YM@1224|Proteobacteria,1SCMX@1236|Gammaproteobacteria,468PH@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Protein of unknown function (DUF1294)	-	-	-	-	-	-	-	-	-	-	-	-	CSD,DUF1294
k141_957_19	1215092.PA6_036_00200	9.37e-11	62.0	2EHT0@1|root,33BIQ@2|Bacteria,1NI2F@1224|Proteobacteria,1SH17@1236|Gammaproteobacteria,1YH1D@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_957_20	1136163.M565_ctg5P1127	3.45e-45	147.0	2E53A@1|root,32ZWE@2|Bacteria,1N77T@1224|Proteobacteria,1SCZC@1236|Gammaproteobacteria,1XYGP@135623|Vibrionales	135623|Vibrionales	S	YrhK-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YrhK
k141_957_21	675816.VIA_002696	3.59e-66	204.0	COG0454@1|root,COG0456@2|Bacteria,1MZQ5@1224|Proteobacteria,1S45R@1236|Gammaproteobacteria,1XXGD@135623|Vibrionales	135623|Vibrionales	K	Acetyltransferase (GNAT) domain	-	-	-	ko:K03826	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_10
k141_957_23	675806.VII_000705	7.57e-66	202.0	COG0346@1|root,COG0346@2|Bacteria,1RH8G@1224|Proteobacteria,1S629@1236|Gammaproteobacteria,1XXM8@135623|Vibrionales	135623|Vibrionales	E	COG0346 Lactoylglutathione lyase and related lyases	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
k141_957_24	1423807.BACO01000050_gene1473	0.0	947.0	COG3507@1|root,COG3507@2|Bacteria,1TP5K@1239|Firmicutes,4HA16@91061|Bacilli,3F4SQ@33958|Lactobacillaceae	91061|Bacilli	G	Belongs to the glycosyl hydrolase 43 family	xynB	-	3.2.1.37	ko:K01198	ko00520,ko01100,map00520,map01100	-	R01433	RC00467	ko00000,ko00001,ko01000	-	GH43	-	DUF1349,Glyco_hydro_43
k141_957_25	862514.HMPREF0623_1203	1.51e-275	762.0	COG2211@1|root,COG2211@2|Bacteria,1TRA5@1239|Firmicutes,4HENT@91061|Bacilli,3F49E@33958|Lactobacillaceae	91061|Bacilli	G	MFS/sugar transport protein	-	-	-	ko:K03292	-	-	-	-	ko00000	2.A.2	-	-	MFS_2
k141_957_27	1238450.VIBNISOn1_1610077	5.8e-303	844.0	COG0514@1|root,COG0514@2|Bacteria,1MVGG@1224|Proteobacteria,1RS89@1236|Gammaproteobacteria,1XT65@135623|Vibrionales	135623|Vibrionales	L	COG0514 Superfamily II DNA helicase	-	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecQ_Zn_bind
k141_957_28	675813.VIB_002861	1.11e-156	448.0	COG0583@1|root,COG0583@2|Bacteria,1MU8N@1224|Proteobacteria,1RN7T@1236|Gammaproteobacteria,1XTGJ@135623|Vibrionales	135623|Vibrionales	K	Transcriptional regulator	cysB	-	-	ko:K13634	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,LysR_substrate
k141_957_29	316274.Haur_1140	3.03e-43	157.0	COG4305@1|root,COG4305@2|Bacteria,2GADE@200795|Chloroflexi,375JZ@32061|Chloroflexia	32061|Chloroflexia	G	Rare lipoprotein A	-	-	-	ko:K20628	-	-	-	-	ko00000	-	-	-	DPBB_1
k141_957_30	223926.28810034	3.89e-152	434.0	COG2240@1|root,COG2240@2|Bacteria,1MVC9@1224|Proteobacteria,1RMIE@1236|Gammaproteobacteria,1XSHI@135623|Vibrionales	135623|Vibrionales	H	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP	pdxY	-	2.7.1.35	ko:K00868	ko00750,ko01100,map00750,map01100	-	R00174,R01909,R02493	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	Phos_pyr_kin
k141_957_31	1232683.ADIMK_3463	1.15e-55	190.0	COG0679@1|root,COG0679@2|Bacteria,1PINE@1224|Proteobacteria,1S1GM@1236|Gammaproteobacteria,469ZR@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Membrane transport protein	-	-	-	ko:K07088	-	-	-	-	ko00000	-	-	-	Mem_trans
k141_957_32	1167006.UWK_02131	1.42e-71	229.0	28K48@1|root,2Z9T8@2|Bacteria,1R4TF@1224|Proteobacteria,42MAD@68525|delta/epsilon subdivisions,2WKEM@28221|Deltaproteobacteria,2MHZD@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4405)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4405
k141_957_34	1348635.BBJY01000014_gene932	0.0	1335.0	COG0403@1|root,COG1003@1|root,COG0403@2|Bacteria,COG1003@2|Bacteria,1MUDP@1224|Proteobacteria,1RND3@1236|Gammaproteobacteria,1XU09@135623|Vibrionales	135623|Vibrionales	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvP	-	1.4.4.2	ko:K00281	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko00002,ko01000	-	-	-	GDC-P
k141_2954_1	1173263.Syn7502_03059	6.28e-40	143.0	COG4748@1|root,COG4748@2|Bacteria,1G4QJ@1117|Cyanobacteria,1H2PZ@1129|Synechococcus	1117|Cyanobacteria	S	PFAM Type I restriction enzyme R protein N terminus (HSDR_N)	-	-	-	ko:K07504	-	-	-	-	ko00000	-	-	-	HSDR_N,HSDR_N_2
k141_2954_3	1136163.M565_ctg1P1207	1.42e-223	646.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1R81Y@1224|Proteobacteria,1RYQ2@1236|Gammaproteobacteria,1XSR3@135623|Vibrionales	135623|Vibrionales	T	COG0642 Signal transduction histidine kinase	cqsS	GO:0000155,GO:0000156,GO:0000160,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0035556,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0060089,GO:0065007,GO:0071704,GO:0140096,GO:1901564	2.7.13.3	ko:K10916	ko02020,ko02024,ko05111,map02020,map02024,map05111	M00513	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,Response_reg
k141_2954_5	1201293.AKXQ01000001_gene2034	3.46e-186	545.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	NT	chemotaxis, protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CHASE3,MCPsignal
k141_2954_6	1348635.BBJY01000001_gene2560	6.75e-270	758.0	COG1018@1|root,COG3217@1|root,COG1018@2|Bacteria,COG3217@2|Bacteria,1MXN2@1224|Proteobacteria,1RMN7@1236|Gammaproteobacteria,1XSP5@135623|Vibrionales	135623|Vibrionales	C	Fe-S protein	VVA0408	-	-	ko:K07140	-	-	-	-	ko00000	-	-	-	FAD_binding_6,Fer2,MOSC,MOSC_N,NAD_binding_1
k141_2954_7	55601.VANGNB10_cII0781	4.6e-47	160.0	28R69@1|root,2ZDKA@2|Bacteria,1P5DZ@1224|Proteobacteria,1SW5A@1236|Gammaproteobacteria,1XWIU@135623|Vibrionales	135623|Vibrionales	S	COG2207 AraC-type DNA-binding domain-containing proteins	VPA0415	-	-	-	-	-	-	-	-	-	-	-	AraC_binding
k141_2954_8	675813.VIB_002416	1.22e-203	570.0	COG0204@1|root,COG0204@2|Bacteria,1MUFH@1224|Proteobacteria,1RNJQ@1236|Gammaproteobacteria,1XSQX@135623|Vibrionales	135623|Vibrionales	I	Phosphate acyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
k141_2954_9	1219065.VPR01S_05_01500	5.01e-06	53.5	COG4886@1|root,COG4886@2|Bacteria,1NF8D@1224|Proteobacteria,1SYIT@1236|Gammaproteobacteria,1XT24@135623|Vibrionales	135623|Vibrionales	S	Leucine-rich repeat (LRR) protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_2954_10	243277.VC_A0919	6.11e-43	142.0	COG3691@1|root,COG3691@2|Bacteria,1NNR5@1224|Proteobacteria,1SHHC@1236|Gammaproteobacteria,1XYHA@135623|Vibrionales	135623|Vibrionales	S	protein conserved in bacteria	VPA0419	-	-	-	-	-	-	-	-	-	-	-	DUF406
k141_2954_11	243277.VC_A0917	3.85e-54	176.0	COG1309@1|root,COG1309@2|Bacteria,1P117@1224|Proteobacteria,1SIAW@1236|Gammaproteobacteria,1XWYZ@135623|Vibrionales	135623|Vibrionales	K	Transcriptional regulator	luxT	-	-	-	-	-	-	-	-	-	-	-	TetR_N
k141_2954_12	29495.EA26_16600	2.06e-193	569.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,1XVE1@135623|Vibrionales	135623|Vibrionales	NT	methyl-accepting chemotaxis protein	-	-	-	-	-	-	-	-	-	-	-	-	Cache_3-Cache_2,MCPsignal
k141_2954_13	1348635.BBJY01000029_gene2057	4.79e-237	658.0	COG2017@1|root,COG2017@2|Bacteria,1MVUY@1224|Proteobacteria,1RQ29@1236|Gammaproteobacteria,1Y214@135623|Vibrionales	135623|Vibrionales	G	Domain of unknown function (DUF4432)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4432
k141_2954_15	1348635.BBJY01000003_gene3739	3.98e-303	832.0	COG0362@1|root,COG0362@2|Bacteria,1MVV8@1224|Proteobacteria,1RM7P@1236|Gammaproteobacteria,1XTAI@135623|Vibrionales	135623|Vibrionales	H	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH	gnd	-	1.1.1.343,1.1.1.44	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	M00004,M00006	R01528,R10221	RC00001,RC00539	ko00000,ko00001,ko00002,ko01000	-	-	-	6PGD,NAD_binding_2
k141_2954_16	1116375.VEJY3_07920	3.32e-118	343.0	COG0363@1|root,COG0363@2|Bacteria,1QXIZ@1224|Proteobacteria,1SB0N@1236|Gammaproteobacteria,1XT94@135623|Vibrionales	135623|Vibrionales	G	COG0363 6-phosphogluconolactonase Glucosamine-6-phosphate isomerase deaminase	pgl	-	3.1.1.31	ko:K01057	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	M00004,M00006,M00008	R02035	RC00537	ko00000,ko00001,ko00002,ko01000	-	-	-	Glucosamine_iso
## 12471 queries scanned
## Total time (seconds): 83.40077257156372
## Rate: 149.53 q/s