## Thu Aug 29 16:10:03 2024 ## emapper-2.1.12 ## /data/home/zhuyingjie/miniforge3/envs/eggnog/bin/emapper.py -i /data/home/zhuyingjie/01_Project/01_metagenome/seagrass/mmseqs_cluster/PRJNA751983/SRR15353283/SRR15353283_p_cluster_rep_seq.fasta --output PRJNA751983_SRR15353283 --data_dir /data/software/eggnog_database -m diamond --sensmode fast --output_dir /data/home/zhuyingjie/01_Project/01_metagenome/seagrass/annotation --temp_dir /data/software/eggnog_database/temp --excel --dbmem --cpu 24 ## #query seed_ortholog evalue score eggNOG_OGs max_annot_lvl COG_category Description Preferred_name GOs EC KEGG_ko KEGG_Pathway KEGG_Module KEGG_Reaction KEGG_rclass BRITE KEGG_TC CAZy BiGG_Reaction PFAMs k141_25_1 237368.SCABRO_01651 4.14e-56 184.0 COG3464@1|root,COG3464@2|Bacteria,2J105@203682|Planctomycetes 203682|Planctomycetes L PFAM Transposase IS66 family - - - ko:K07484 - - - - ko00000 - - - DDE_Tnp_IS66,zf-IS66 k141_65_5 388051.AUFE01000009_gene1846 2.54e-21 89.7 COG4570@1|root,COG4570@2|Bacteria,1N32D@1224|Proteobacteria,2VSY6@28216|Betaproteobacteria,1K929@119060|Burkholderiaceae 28216|Betaproteobacteria L Endodeoxyribonuclease RusA - - - - - - - - - - - - RusA k141_464_1 83406.HDN1F_04090 1.02e-41 147.0 COG0502@1|root,COG0502@2|Bacteria,1MVFF@1224|Proteobacteria,1RMEQ@1236|Gammaproteobacteria,1J4ND@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria H Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism bioB GO:0003674,GO:0003824,GO:0004076,GO:0005488,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0017144,GO:0018130,GO:0019752,GO:0032787,GO:0034641,GO:0042364,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.8.1.6 ko:K01012 ko00780,ko01100,map00780,map01100 M00123,M00573,M00577 R01078 RC00441 ko00000,ko00001,ko00002,ko01000 - - iZ_1308.Z0994 BATS,Radical_SAM k141_549_1 102129.Lepto7375DRAFT_5349 1.28e-80 248.0 COG3676@1|root,COG3677@1|root,COG3676@2|Bacteria,COG3677@2|Bacteria,1GBBG@1117|Cyanobacteria,1HG5G@1150|Oscillatoriales 1117|Cyanobacteria L Transposase zinc-ribbon domain - - - - - - - - - - - - DDE_Tnp_IS1595,Zn_Tnp_IS1595 k141_425_1 234267.Acid_1623 1.15e-25 104.0 COG2801@1|root,COG2801@2|Bacteria,3Y821@57723|Acidobacteria 57723|Acidobacteria L Integrase core domain - - - - - - - - - - - - rve_3 k141_201_1 316274.Haur_4462 3.24e-41 144.0 COG0667@1|root,COG0667@2|Bacteria,2G809@200795|Chloroflexi 200795|Chloroflexi C PFAM aldo keto reductase - - - - - - - - - - - - Aldo_ket_red k141_117_2 753084.F4YCM7_9CAUD 1.04e-28 105.0 4QCEX@10239|Viruses,4QV7Q@35237|dsDNA viruses no RNA stage,4QU8B@28883|Caudovirales 28883|Caudovirales - - - - - - - - - - - - - - - k141_66_1 880073.Calab_2523 1.22e-24 109.0 COG1042@1|root,COG1042@2|Bacteria,2NNW5@2323|unclassified Bacteria 2|Bacteria C synthetase (ADP forming), alpha - - 6.2.1.13 ko:K01905,ko:K22224 ko00010,ko00620,ko00640,ko01100,ko01120,map00010,map00620,map00640,map01100,map01120 - R00229,R00920 RC00004,RC00012,RC00014 ko00000,ko00001,ko01000,ko01004 - - - ATP-grasp_5,CoA_binding_2,Succ_CoA_lig k141_513_1 1128427.KB904821_gene4207 1.06e-15 84.0 COG0515@1|root,COG0642@1|root,COG3899@1|root,COG0515@2|Bacteria,COG2205@2|Bacteria,COG3899@2|Bacteria,1GBKM@1117|Cyanobacteria,1H7D9@1150|Oscillatoriales 1117|Cyanobacteria KLT Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - - - - - - - - - - AAA_16,GAF,GGDEF,HATPase_c,HisKA,PAS_3,PAS_4,Pkinase,Response_reg,SpoIIE k141_352_1 1229909.NSED_04590 4.36e-33 129.0 COG1253@1|root,arCOG00626@2157|Archaea,41T1G@651137|Thaumarchaeota 651137|Thaumarchaeota S Transporter associated domain - - - - - - - - - - - - CBS,CorC_HlyC,DUF21 k141_88_1 1246459.KB898353_gene347 1.93e-17 88.6 COG1345@1|root,COG2931@1|root,COG2982@1|root,COG3209@1|root,COG3210@1|root,COG5295@1|root,COG1345@2|Bacteria,COG2931@2|Bacteria,COG2982@2|Bacteria,COG3209@2|Bacteria,COG3210@2|Bacteria,COG5295@2|Bacteria,1MU7T@1224|Proteobacteria,2TRVY@28211|Alphaproteobacteria,4BB16@82115|Rhizobiaceae 28211|Alphaproteobacteria Q COG2931 RTX toxins and related Ca2 -binding proteins - - - - - - - - - - - - DUF4214,DUF4347,HCBP_related,He_PIG,HemolysinCabind,Metallophos,P_proprotein,Peptidase_S8 k141_45_1 501479.ACNW01000062_gene2740 3.47e-35 136.0 28HMZ@1|root,2Z7WD@2|Bacteria,1MU3Q@1224|Proteobacteria,2TSGX@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Protein of unknown function (DUF3604) - - - - - - - - - - - - DUF3604 k141_440_2 467661.RKLH11_1968 3.42e-20 92.8 COG3119@1|root,COG3119@2|Bacteria,1MUJH@1224|Proteobacteria,2U2E4@28211|Alphaproteobacteria 28211|Alphaproteobacteria P Sulfatase - - 3.1.6.1 ko:K01130 ko00140,ko00600,map00140,map00600 - R03980,R04856 RC00128,RC00231 ko00000,ko00001,ko01000 - - - Sulfatase,Sulfatase_C k141_89_1 411489.CLOL250_02680 2.86e-22 89.4 arCOG05874@1|root,2ZJ01@2|Bacteria,1VARV@1239|Firmicutes,24NY6@186801|Clostridia,36TQR@31979|Clostridiaceae 186801|Clostridia - - - - - - - - - - - - - - - k141_264_1 395493.BegalDRAFT_3002 5.3e-61 198.0 COG0169@1|root,COG0169@2|Bacteria,1MVH4@1224|Proteobacteria,1RPB7@1236|Gammaproteobacteria,460E1@72273|Thiotrichales 72273|Thiotrichales E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) aroE - 1.1.1.25 ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R02413 RC00206 ko00000,ko00001,ko00002,ko01000 - - - Shikimate_DH,Shikimate_dh_N k141_397_1 748247.AZKH_1956 5.07e-38 143.0 COG5361@1|root,COG5361@2|Bacteria,1PJY5@1224|Proteobacteria,2W9FE@28216|Betaproteobacteria,2KZE5@206389|Rhodocyclales 206389|Rhodocyclales S Protein of unknown function (DUF1254) - - - - - - - - - - - - DUF1214,DUF1254 k141_176_1 234267.Acid_3115 7.79e-37 143.0 COG0457@1|root,COG3710@1|root,COG3899@1|root,COG0457@2|Bacteria,COG3710@2|Bacteria,COG3899@2|Bacteria,3Y2KZ@57723|Acidobacteria 57723|Acidobacteria K AAA ATPase domain - - - - - - - - - - - - AAA_16,Trans_reg_C k141_614_1 272943.RSP_3667 8e-19 91.3 COG1361@1|root,COG3188@1|root,COG1361@2|Bacteria,COG3188@2|Bacteria,1R5G4@1224|Proteobacteria,2UC86@28211|Alphaproteobacteria,1FCGH@1060|Rhodobacter 28211|Alphaproteobacteria M TIGRFAM conserved repeat domain - - - - - - - - - - - - DUF11,SdrD_B k141_398_1 598467.BrE312_0096 3.36e-36 137.0 COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,1RNW9@1236|Gammaproteobacteria 1236|Gammaproteobacteria E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family - - - - - - - - - - - - Aminotran_3 k141_572_1 558173.CDOO_11140 2.91e-05 47.8 COG3127@1|root,COG3127@2|Bacteria,2H37M@201174|Actinobacteria,22K1N@1653|Corynebacteriaceae 201174|Actinobacteria Q ABC-type antimicrobial peptide transport system, permease component - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD k141_572_2 1279017.AQYJ01000027_gene1776 3.46e-29 111.0 COG1136@1|root,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,1RSA2@1236|Gammaproteobacteria,465P9@72275|Alteromonadaceae 1236|Gammaproteobacteria V ATPases associated with a variety of cellular activities tptC - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran k141_265_1 545264.KB898744_gene2062 3.33e-110 331.0 COG0469@1|root,COG0469@2|Bacteria,1MU21@1224|Proteobacteria,1RMW3@1236|Gammaproteobacteria,1WXEF@135613|Chromatiales 135613|Chromatiales G Belongs to the pyruvate kinase family - - 2.7.1.40 ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 M00001,M00002,M00049,M00050 R00200,R00430,R01138,R01858,R02320 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - PK,PK_C k141_528_1 589865.DaAHT2_0018 2.07e-32 126.0 COG4262@1|root,COG4262@2|Bacteria 2|Bacteria H Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine speE - 2.5.1.16 ko:K00797 ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100 M00034,M00133 R01920,R02869,R08359 RC00021,RC00053 ko00000,ko00001,ko00002,ko01000 - - - Spermine_synth k141_528_2 204669.Acid345_3835 1.13e-05 48.1 COG0531@1|root,COG0531@2|Bacteria,3Y6HV@57723|Acidobacteria,2JMCG@204432|Acidobacteriia 204432|Acidobacteriia E Amino acid permease - - - ko:K03294 - - - - ko00000 2.A.3.2 - - AA_permease_2 k141_442_1 1089439.KB902267_gene5 8.31e-32 112.0 arCOG05874@1|root,2ZJ01@2|Bacteria,1N8VY@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k141_400_2 96561.Dole_1364 2.36e-33 129.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,2MI07@213118|Desulfobacterales 28221|Deltaproteobacteria T PFAM response regulator receiver - - - ko:K02481,ko:K07712 ko02020,map02020 M00497 - - ko00000,ko00001,ko00002,ko02022 - - - HTH_8,Response_reg,Sigma54_activat k141_48_1 1121943.KB899995_gene806 1.58e-64 213.0 COG3333@1|root,COG3333@2|Bacteria,1MUKR@1224|Proteobacteria,1RMQB@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Tripartite tricarboxylate transporter TctA - - - - - - - - - - - - TctA k141_137_1 1045856.EcWSU1_03228 2.89e-34 136.0 COG3961@1|root,COG3961@2|Bacteria,1MW2F@1224|Proteobacteria,1RQFY@1236|Gammaproteobacteria,3X0X7@547|Enterobacter 1236|Gammaproteobacteria C Belongs to the TPP enzyme family ipdC - 4.1.1.1,4.1.1.74 ko:K01568,ko:K04103 ko00010,ko00380,ko01100,ko01110,ko01130,map00010,map00380,map01100,map01110,map01130 - R00014,R00755,R01974 RC00027,RC00375,RC00506,RC02744 ko00000,ko00001,ko01000 - - - TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N k141_574_1 1255043.TVNIR_1736 9.8e-72 223.0 COG0338@1|root,COG0338@2|Bacteria,1QDNB@1224|Proteobacteria,1RXZB@1236|Gammaproteobacteria 1236|Gammaproteobacteria L D12 class N6 adenine-specific DNA methyltransferase - - - - - - - - - - - - MethyltransfD12 k141_401_1 1173020.Cha6605_1310 4.28e-26 109.0 COG5659@1|root,COG5659@2|Bacteria 2|Bacteria L transposition - - - - - - - - - - - - DDE_5 k141_270_1 765912.Thimo_1490 7.75e-23 91.3 COG0636@1|root,COG0636@2|Bacteria,1REA9@1224|Proteobacteria,1S51I@1236|Gammaproteobacteria,1WY7C@135613|Chromatiales 135613|Chromatiales C ATP synthase subunit C - - - ko:K02124 ko00190,ko01100,map00190,map01100 M00159 - - ko00000,ko00001,ko00002 3.A.2.2,3.A.2.3 - - ATP-synt_C k141_270_2 1123393.KB891326_gene142 4.32e-17 77.8 COG1436@1|root,COG1436@2|Bacteria,1MZUE@1224|Proteobacteria,2W5EY@28216|Betaproteobacteria 28216|Betaproteobacteria C ATP synthase (F/14-kDa) subunit - - - - - - - - - - - - ATP-synt_F k141_402_1 631362.Thi970DRAFT_02456 6.29e-08 53.5 COG0735@1|root,COG0735@2|Bacteria,1MZIW@1224|Proteobacteria,1S5ZI@1236|Gammaproteobacteria,1WYD6@135613|Chromatiales 135613|Chromatiales P Belongs to the Fur family - - - ko:K09823 ko02024,map02024 - - - ko00000,ko00001,ko03000 - - - FUR k141_402_2 765912.Thimo_2510 2.43e-35 129.0 COG1108@1|root,COG1108@2|Bacteria,1MVC2@1224|Proteobacteria,1RPYF@1236|Gammaproteobacteria,1WX5H@135613|Chromatiales 135613|Chromatiales P pfam abc-3 - - - ko:K09816 ko02010,map02010 M00242 - - ko00000,ko00001,ko00002,ko02000 3.A.1.15.3,3.A.1.15.5 - - ABC-3 k141_444_1 557598.LHK_00049 9.78e-25 102.0 COG0446@1|root,COG1902@1|root,COG0446@2|Bacteria,COG1902@2|Bacteria,1MVE0@1224|Proteobacteria,2VIW3@28216|Betaproteobacteria,2KPT3@206351|Neisseriales 206351|Neisseriales C NADH:flavin oxidoreductase / NADH oxidase family fadH - 1.3.1.34 ko:K00219 - - - - ko00000,ko01000 - - - Oxidored_FMN,Pyr_redox_2 k141_138_1 1270193.JARP01000002_gene658 5.25e-17 86.7 COG4313@1|root,COG4313@2|Bacteria,4NW4N@976|Bacteroidetes,1I60R@117743|Flavobacteriia,2NVHT@237|Flavobacterium 976|Bacteroidetes C Putative MetA-pathway of phenol degradation - - - - - - - - - - - - Phenol_MetA_deg k141_575_1 870187.Thini_3774 3.11e-83 263.0 COG0493@1|root,COG1143@1|root,COG0493@2|Bacteria,COG1143@2|Bacteria,1MU2H@1224|Proteobacteria,1RREP@1236|Gammaproteobacteria,463NI@72273|Thiotrichales 72273|Thiotrichales C Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - - - - - - - - - - Fer4_20,Fer4_7,Pyr_redox_2 k141_575_2 1123399.AQVE01000035_gene3175 1.5e-33 128.0 COG0493@1|root,COG1143@1|root,COG0493@2|Bacteria,COG1143@2|Bacteria,1MU2H@1224|Proteobacteria,1RREP@1236|Gammaproteobacteria,463NI@72273|Thiotrichales 72273|Thiotrichales C Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - - - - - - - - - - Fer4_20,Fer4_7,Pyr_redox_2 k141_227_1 1317122.ATO12_18700 7.06e-22 101.0 COG2304@1|root,COG2931@1|root,COG3291@1|root,COG2304@2|Bacteria,COG2931@2|Bacteria,COG3291@2|Bacteria,4PNMJ@976|Bacteroidetes,1I88G@117743|Flavobacteriia,2YIC8@290174|Aquimarina 976|Bacteroidetes Q Integrin alpha (beta-propellor repeats). - - - - - - - - - - - - CHU_C,Calx-beta,FG-GAP,HYR k141_529_1 160492.XF_0511 5.93e-31 129.0 COG0740@1|root,COG0740@2|Bacteria,1MUQ9@1224|Proteobacteria,1RRQA@1236|Gammaproteobacteria,1X3TK@135614|Xanthomonadales 135614|Xanthomonadales OU Belongs to the peptidase S14 family - - - - - - - - - - - - CLP_protease,Mu-like_gpT k141_360_1 87626.PTD2_05250 5.53e-116 344.0 COG0055@1|root,COG0055@2|Bacteria,1MUFU@1224|Proteobacteria,1RN6U@1236|Gammaproteobacteria,2Q02E@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits atpD GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0036442,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 3.6.3.14 ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 - e_coli_core.b3732,iAF1260.b3732,iAPECO1_1312.APECO1_2729,iB21_1397.B21_03560,iBWG_1329.BWG_3423,iE2348C_1286.E2348C_4042,iEC042_1314.EC042_4119,iEC55989_1330.EC55989_4207,iECABU_c1320.ECABU_c42160,iECBD_1354.ECBD_4300,iECB_1328.ECB_03616,iECDH10B_1368.ECDH10B_3919,iECDH1ME8569_1439.ECDH1ME8569_3620,iECD_1391.ECD_03616,iECED1_1282.ECED1_4422,iECH74115_1262.ECH74115_5168,iECIAI1_1343.ECIAI1_3916,iECIAI39_1322.ECIAI39_4336,iECNA114_1301.ECNA114_3881,iECO103_1326.ECO103_4426,iECO111_1330.ECO111_4566,iECO26_1355.ECO26_4846,iECOK1_1307.ECOK1_4181,iECP_1309.ECP_3931,iECS88_1305.ECS88_4154,iECSE_1348.ECSE_4022,iECSF_1327.ECSF_3580,iECSP_1301.ECSP_4782,iECUMN_1333.ECUMN_4262,iECW_1372.ECW_m4035,iECs_1301.ECs4674,iEKO11_1354.EKO11_4613,iETEC_1333.ETEC_4023,iEcDH1_1363.EcDH1_4235,iEcE24377_1341.EcE24377A_4247,iEcSMS35_1347.EcSMS35_4100,iEcolC_1368.EcolC_4262,iG2583_1286.G2583_4528,iJO1366.b3732,iJR904.b3732,iLF82_1304.LF82_0194,iNRG857_1313.NRG857_18585,iPC815.YPO4121,iSFV_1184.SFV_3758,iSF_1195.SF3812,iSFxv_1172.SFxv_4154,iSSON_1240.SSON_3887,iS_1188.S3956,iSbBS512_1146.SbBS512_E4189,iUMN146_1321.UM146_18850,iUMNK88_1353.UMNK88_4544,iUTI89_1310.UTI89_C4285,iWFL_1372.ECW_m4035,iY75_1357.Y75_RS18410,iZ_1308.Z5230,ic_1306.c4658 ATP-synt_ab,ATP-synt_ab_N k141_97_1 247633.GP2143_00227 5.17e-25 96.3 COG0102@1|root,COG0102@2|Bacteria,1RA11@1224|Proteobacteria,1S280@1236|Gammaproteobacteria,1J5P3@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly rplM GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0017148,GO:0019222,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034641,GO:0034645,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0070180,GO:0071704,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 - ko:K02871 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L13 k141_272_2 391623.TERMP_01127 1.89e-07 53.5 COG1052@1|root,arCOG01755@2157|Archaea,2XVDY@28890|Euryarchaeota,2432P@183968|Thermococci 183968|Thermococci C glyoxylate reductase activity gyaR GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016616,GO:0016618,GO:0030267,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.1.1.26 ko:K00015 ko00630,ko01100,ko01110,ko01120,map00630,map01100,map01110,map01120 - R00717,R01388 RC00031,RC00042 ko00000,ko00001,ko01000 - - - 2-Hacid_dh,2-Hacid_dh_C k141_576_2 765914.ThisiDRAFT_1930 7.58e-15 71.2 COG4657@1|root,COG4657@2|Bacteria,1MU8X@1224|Proteobacteria,1RQDN@1236|Gammaproteobacteria,1WW9M@135613|Chromatiales 135613|Chromatiales U Part of a membrane complex involved in electron transport - - - ko:K03617 - - - - ko00000 - - - Rnf-Nqr k141_52_2 1121396.KB893060_gene2865 2.01e-62 195.0 COG0735@1|root,COG0735@2|Bacteria,1N4Z7@1224|Proteobacteria,42UD5@68525|delta/epsilon subdivisions,2WQSV@28221|Deltaproteobacteria,2MM4F@213118|Desulfobacterales 28221|Deltaproteobacteria P Ferric uptake regulator family - - - ko:K03711 - - - - ko00000,ko03000 - - - FUR k141_446_1 314278.NB231_09623 3.57e-111 333.0 COG0399@1|root,COG0399@2|Bacteria,1MUMJ@1224|Proteobacteria,1T3U5@1236|Gammaproteobacteria,1X1MF@135613|Chromatiales 135613|Chromatiales M Putative transposase - - - - - - - - - - - - Y2_Tnp k141_361_1 580340.Tlie_1465 6.53e-69 234.0 COG0493@1|root,COG1894@1|root,COG0493@2|Bacteria,COG1894@2|Bacteria,3TAPD@508458|Synergistetes 508458|Synergistetes C Pyridine nucleotide-disulphide oxidoreductase - - 1.6.5.3 ko:K00335 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - 2Fe-2S_thioredx,Complex1_51K,Fer4_20,NADH_4Fe-4S,Pyr_redox_2,SLBB k141_492_1 1121286.AUMT01000026_gene2888 9.98e-07 46.6 2DH2B@1|root,2ZY57@2|Bacteria,4PCK5@976|Bacteroidetes,1IK0A@117743|Flavobacteriia,3ZSYU@59732|Chryseobacterium 976|Bacteroidetes - - - - - - - - - - - - - - - k141_273_1 1430440.MGMSRv2_2122 1.19e-29 114.0 COG0798@1|root,COG0798@2|Bacteria,1MUXY@1224|Proteobacteria,2TSVJ@28211|Alphaproteobacteria,2JQSA@204441|Rhodospirillales 204441|Rhodospirillales P COG0798 Arsenite efflux pump ACR3 and related permeases - - - ko:K03325 - - - - ko00000,ko02000 2.A.59 - - SBF k141_273_2 1046714.AMRX01000008_gene1206 3.91e-15 74.3 COG1944@1|root,COG1944@2|Bacteria,1MV7K@1224|Proteobacteria,1RN47@1236|Gammaproteobacteria,464WG@72275|Alteromonadaceae 1236|Gammaproteobacteria O redox protein, regulator of disulfide bond formation ycaO GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018193,GO:0018197,GO:0018198,GO:0018339,GO:0019538,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0047429,GO:0047693,GO:0071704,GO:1901564 - ko:K09136 - - - - ko00000,ko03009 - - - OsmC,YcaO k141_183_1 1415779.JOMH01000001_gene2944 3.21e-54 186.0 COG1080@1|root,COG1080@2|Bacteria,1MUT8@1224|Proteobacteria,1RN6R@1236|Gammaproteobacteria,1X33X@135614|Xanthomonadales 135614|Xanthomonadales G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) ptsI - 2.7.3.9 ko:K08483 ko02060,map02060 - - - ko00000,ko00001,ko01000,ko02000 8.A.7 - - PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C k141_318_1 1472716.KBK24_0120135 1.03e-28 117.0 COG3464@1|root,COG3464@2|Bacteria,1R8HI@1224|Proteobacteria,2VT67@28216|Betaproteobacteria,1KHTC@119060|Burkholderiaceae 28216|Betaproteobacteria L Transposase - - - - - - - - - - - - DDE_Tnp_ISL3,TrfA k141_494_1 314278.NB231_05596 4.64e-20 88.2 COG0707@1|root,COG0707@2|Bacteria,1MVIB@1224|Proteobacteria,1RMQ3@1236|Gammaproteobacteria,1WWB9@135613|Chromatiales 135613|Chromatiales M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) murG - 2.4.1.227 ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 - R05032,R05662 RC00005,RC00049 ko00000,ko00001,ko01000,ko01011 - GT28 - Glyco_tran_28_C,Glyco_transf_28 k141_494_2 1323663.AROI01000006_gene3007 1.2e-22 97.8 COG0772@1|root,COG0772@2|Bacteria,1MVDB@1224|Proteobacteria,1RMIV@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Peptidoglycan polymerase that is essential for cell division ftsW GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0008360,GO:0009987,GO:0015647,GO:0015648,GO:0015835,GO:0015836,GO:0016020,GO:0016021,GO:0022603,GO:0022604,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0032153,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0051179,GO:0051234,GO:0051301,GO:0055085,GO:0065007,GO:0065008,GO:0071702,GO:0071705,GO:0071944,GO:1901264,GO:1901505 - ko:K03588 ko04112,map04112 - - - ko00000,ko00001,ko02000,ko03036 2.A.103.1 - - FTSW_RODA_SPOVE k141_448_1 156889.Mmc1_2995 2.06e-23 96.7 COG2863@1|root,COG2863@2|Bacteria,1N7W9@1224|Proteobacteria,2TSFV@28211|Alphaproteobacteria 28211|Alphaproteobacteria C cytochrome - - - ko:K17230 ko00920,ko01120,map00920,map01120 - R09499 - ko00000,ko00001 - - - Cytochrom_C,Cytochrome_CBB3 k141_9_1 1121921.KB898706_gene2539 3.82e-08 60.5 2C2C7@1|root,2Z85G@2|Bacteria,1PD07@1224|Proteobacteria,1RP6G@1236|Gammaproteobacteria,2PMYR@256005|Alteromonadales genera incertae sedis 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_184_1 395493.BegalDRAFT_1923 8.75e-06 45.1 COG1925@1|root,COG1925@2|Bacteria,1N6RM@1224|Proteobacteria,1SCXX@1236|Gammaproteobacteria,461HK@72273|Thiotrichales 72273|Thiotrichales G TIGRFAM Phosphotransferase System HPr (HPr) Family - - - ko:K11189 - - - - ko00000,ko02000 4.A.2.1 - - PTS-HPr k141_184_2 391615.ABSJ01000054_gene1477 1.84e-21 90.1 COG2893@1|root,COG2893@2|Bacteria,1PCBM@1224|Proteobacteria,1SX8Z@1236|Gammaproteobacteria,1JBFI@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria G PTS system fructose IIA component - - - - - - - - - - - - EIIA-man k141_54_1 1379270.AUXF01000005_gene747 9.85e-82 267.0 COG0542@1|root,COG0542@2|Bacteria,1ZT9Z@142182|Gemmatimonadetes 142182|Gemmatimonadetes O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE clpB - - ko:K03695 ko04213,map04213 - - - ko00000,ko00001,ko03110 - - - AAA,AAA_2,ClpB_D2-small,Clp_N k141_231_1 118163.Ple7327_2980 1.16e-10 61.6 COG3547@1|root,COG3547@2|Bacteria,1G4PF@1117|Cyanobacteria 1117|Cyanobacteria L PFAM Transposase - - - - - - - - - - - - DEDD_Tnp_IS110,Transposase_20 k141_231_2 555778.Hneap_2214 1.25e-45 160.0 COG3547@1|root,COG3547@2|Bacteria,1QYJU@1224|Proteobacteria,1RN0A@1236|Gammaproteobacteria,1WZMA@135613|Chromatiales 135613|Chromatiales L transposase IS116 IS110 IS902 family - - - - - - - - - - - - DEDD_Tnp_IS110,Transposase_20 k141_668_1 1496688.ER33_14890 3.27e-48 174.0 COG2982@1|root,COG2982@2|Bacteria 2|Bacteria M Protein involved in outer membrane biogenesis - - - - - - - - - - - - Big_2,DUF4347,DctA-YdbH,Flg_new,He_PIG,SdrD_B k141_495_1 566466.NOR53_2312 2.65e-79 243.0 COG2801@1|root,COG2801@2|Bacteria 2|Bacteria L transposition - - - ko:K07497 - - - - ko00000 - - - HTH_21,rve k141_363_1 690850.Desaf_2037 3.82e-64 220.0 COG2208@1|root,COG2770@1|root,COG2208@2|Bacteria,COG2770@2|Bacteria,1MXJQ@1224|Proteobacteria,42MFQ@68525|delta/epsilon subdivisions,2WIJ4@28221|Deltaproteobacteria,2M7Z5@213115|Desulfovibrionales 28221|Deltaproteobacteria KT SMART protein phosphatase 2C domain protein - - 3.1.3.3 ko:K07315 - - - - ko00000,ko01000,ko03021 - - - Cache_3-Cache_2,HAMP,SpoIIE,dCache_1,dCache_2 k141_409_1 570952.ATVH01000015_gene1476 1.18e-20 96.3 COG4425@1|root,COG4425@2|Bacteria,1MXSU@1224|Proteobacteria,2TV9M@28211|Alphaproteobacteria 28211|Alphaproteobacteria S membrane - - - - - - - - - - - - Abhydrolase_9,Abhydrolase_9_N k141_533_1 1469607.KK073768_gene307 9.49e-53 176.0 COG3385@1|root,COG3385@2|Bacteria,1G2W3@1117|Cyanobacteria 1117|Cyanobacteria L PFAM Transposase DDE domain - - - - - - - - - - - - DDE_Tnp_1 k141_145_1 1196029.ALIM01000045_gene4501 0.000928 40.0 2DR8Z@1|root,33AQV@2|Bacteria,1VK7N@1239|Firmicutes,4HRWZ@91061|Bacilli,1ZISI@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_581_1 641491.DND132_0412 1.64e-48 166.0 COG0618@1|root,COG0618@2|Bacteria,1MX0B@1224|Proteobacteria,42P48@68525|delta/epsilon subdivisions,2WIUR@28221|Deltaproteobacteria,2M974@213115|Desulfovibrionales 28221|Deltaproteobacteria S 3'(2'),5'-bisphosphate nucleotidase activity - - - - - - - - - - - - - k141_450_1 522306.CAP2UW1_3683 2.13e-23 99.4 COG5433@1|root,COG5433@2|Bacteria,1MXI8@1224|Proteobacteria,2W66H@28216|Betaproteobacteria 28216|Betaproteobacteria L PFAM Transposase, IS4-like - - - - - - - - - - - - - k141_320_1 882.DVU_0173 1.23e-54 193.0 COG0243@1|root,COG0243@2|Bacteria,1P01N@1224|Proteobacteria,42M9D@68525|delta/epsilon subdivisions,2WJ43@28221|Deltaproteobacteria,2M8UY@213115|Desulfovibrionales 28221|Deltaproteobacteria C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - 1.8.5.5 ko:K08352 ko00920,ko01120,map00920,map01120 - R10149 RC02823 ko00000,ko00001,ko01000,ko02000 5.A.3.5 - - Molybdop_Fe4S4,Molybdopterin,Molydop_binding k141_364_1 335543.Sfum_0943 7.35e-62 197.0 COG4566@1|root,COG4566@2|Bacteria,1R47Z@1224|Proteobacteria,43065@68525|delta/epsilon subdivisions,2WV8S@28221|Deltaproteobacteria 28221|Deltaproteobacteria K helix_turn_helix, Lux Regulon - - - - - - - - - - - - GerE,Response_reg k141_411_1 1211035.CD30_15240 0.000124 44.7 COG3344@1|root,COG3344@2|Bacteria,1TP9A@1239|Firmicutes,4HF4R@91061|Bacilli,3J03Q@400634|Lysinibacillus 91061|Bacilli L Group II intron, maturase-specific domain - - - - - - - - - - - - GIIM,RVT_1 k141_187_1 1255043.TVNIR_2992 1.79e-63 206.0 COG1850@1|root,COG1850@2|Bacteria,1MWEB@1224|Proteobacteria,1RRMX@1236|Gammaproteobacteria,1WWEJ@135613|Chromatiales 135613|Chromatiales G RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site cbbL - 4.1.1.39 ko:K01601 ko00630,ko00710,ko01100,ko01120,ko01200,map00630,map00710,map01100,map01120,map01200 M00165,M00166,M00532 R00024,R03140 RC00172,RC00859 ko00000,ko00001,ko00002,ko01000 - - - RuBisCO_large,RuBisCO_large_N k141_321_1 396588.Tgr7_0332 1.38e-37 135.0 COG0702@1|root,COG0702@2|Bacteria,1MW54@1224|Proteobacteria,1RNS7@1236|Gammaproteobacteria,1WXE7@135613|Chromatiales 135613|Chromatiales GM NAD-dependent epimerase dehydratase - - 1.6.5.3,1.6.99.3 ko:K00329,ko:K00356 ko00190,map00190 - R11945 RC00061 ko00000,ko00001,ko01000 - - - Epimerase,NAD_binding_10 k141_321_2 1038922.PflQ2_1809 1.11e-06 49.7 COG0277@1|root,COG0277@2|Bacteria,1MU6Y@1224|Proteobacteria,1RQX2@1236|Gammaproteobacteria,1YMPJ@136843|Pseudomonas fluorescens group 1236|Gammaproteobacteria C Glycolate oxidase subunit GlcD glcD GO:0003674,GO:0003824,GO:0006066,GO:0006082,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009441,GO:0009987,GO:0016054,GO:0016491,GO:0016614,GO:0017144,GO:0019154,GO:0019752,GO:0032787,GO:0033554,GO:0034308,GO:0034310,GO:0042737,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046164,GO:0046296,GO:0046395,GO:0050896,GO:0051716,GO:0055114,GO:0071704,GO:0072329,GO:1901575,GO:1901615,GO:1901616 1.1.3.15 ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 - R00475 RC00042 ko00000,ko00001,ko01000 - - iJN746.PP_3745,iLF82_1304.LF82_0831,iNRG857_1313.NRG857_14750 FAD-oxidase_C,FAD_binding_4 k141_582_1 391595.RLO149_c031200 4.72e-15 82.0 COG2885@1|root,COG2911@1|root,COG2931@1|root,COG2885@2|Bacteria,COG2911@2|Bacteria,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,2TRVY@28211|Alphaproteobacteria,2P3XE@2433|Roseobacter 28211|Alphaproteobacteria Q COG2931 RTX toxins and related Ca2 -binding proteins - - 3.4.24.40 ko:K01406,ko:K07004 ko01503,map01503 - - - ko00000,ko00001,ko01000,ko01002 - - - An_peroxidase,Cadherin,Calx-beta,Exo_endo_phos,HemolysinCabind,Metallophos,Peptidase_M10_C k141_365_1 1049564.TevJSym_ad01590 6.71e-101 306.0 COG3303@1|root,COG3303@2|Bacteria,1P8CP@1224|Proteobacteria,1RQGG@1236|Gammaproteobacteria 1236|Gammaproteobacteria C Seven times multi-haem cytochrome CxxCH - - - - - - - - - - - - Cytochrome_C554,Multi-haem_cyto k141_56_1 1232437.KL661961_gene3044 1.59e-57 199.0 COG0243@1|root,COG0243@2|Bacteria,1P01N@1224|Proteobacteria,42M9D@68525|delta/epsilon subdivisions,2WJ43@28221|Deltaproteobacteria,2MI8A@213118|Desulfobacterales 28221|Deltaproteobacteria C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - 1.8.5.5 ko:K08352 ko00920,ko01120,map00920,map01120 - R10149 RC02823 ko00000,ko00001,ko01000,ko02000 5.A.3.5 - - Molybdop_Fe4S4,Molybdopterin,Molydop_binding k141_498_2 1123284.KB899044_gene763 5.7e-16 81.3 COG0370@1|root,COG0370@2|Bacteria,1TP7E@1239|Firmicutes,4HBCS@91061|Bacilli,26PI4@186821|Sporolactobacillaceae 91061|Bacilli P Ferrous iron transport protein B C terminus feoB - - ko:K04759 - - - - ko00000,ko02000 9.A.8.1 - iSB619.SA_RS13395 FeoB_C,FeoB_N,Gate k141_336_1 710686.Mycsm_01667 4.75e-28 110.0 COG1250@1|root,COG1250@2|Bacteria,2GNXI@201174|Actinobacteria,2377R@1762|Mycobacteriaceae 201174|Actinobacteria I 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain lcdH - 1.1.1.108 ko:K05556,ko:K17735 ko01057,ko01130,map01057,map01130 M00779 R09306,R09307,R09308 RC02484,RC02485 ko00000,ko00001,ko00002,ko01000,ko01008 - - - 3HCDH,3HCDH_N k141_336_2 1231336.L248_1776 3.51e-18 84.7 COG1250@1|root,COG1250@2|Bacteria,1TPJS@1239|Firmicutes,4HA59@91061|Bacilli,3F4SY@33958|Lactobacillaceae 91061|Bacilli I 3-hydroxyacyl-CoA dehydrogenase - - 1.1.1.157 ko:K00074 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 - R01976,R05576,R06941 RC00029,RC00117 ko00000,ko00001,ko01000 - - - 3HCDH,3HCDH_N k141_552_1 870187.Thini_0172 2.36e-81 265.0 COG0188@1|root,COG0188@2|Bacteria,1MUGG@1224|Proteobacteria,1RN03@1236|Gammaproteobacteria,45ZYT@72273|Thiotrichales 72273|Thiotrichales L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner gyrA - 5.99.1.3 ko:K02469 - - - - ko00000,ko01000,ko03032,ko03400 - - - DNA_gyraseA_C,DNA_topoisoIV k141_381_1 1167006.UWK_02099 8.24e-65 212.0 COG0448@1|root,COG0448@2|Bacteria,1MVTC@1224|Proteobacteria,42Y4X@68525|delta/epsilon subdivisions,2WUQC@28221|Deltaproteobacteria,2MPZ6@213118|Desulfobacterales 28221|Deltaproteobacteria G Belongs to the bacterial plant glucose-1-phosphate adenylyltransferase family - - 2.7.7.27,2.7.7.91 ko:K00975,ko:K20427 ko00500,ko00520,ko00525,ko01100,ko01110,ko01130,ko02026,map00500,map00520,map00525,map01100,map01110,map01130,map02026 M00565,M00814 R00948,R11237,R11246,R11402 RC00002 ko00000,ko00001,ko00002,ko01000 - - - NTP_transferase k141_248_1 1265505.ATUG01000002_gene1400 3.89e-89 266.0 COG0655@1|root,COG0655@2|Bacteria,1RK1Z@1224|Proteobacteria,42TDB@68525|delta/epsilon subdivisions,2WPKK@28221|Deltaproteobacteria,2MQ2I@213118|Desulfobacterales 28221|Deltaproteobacteria S NADPH-dependent FMN reductase - - - - - - - - - - - iAF987.Gmet_2647 FMN_red k141_204_1 1188256.BASI01000003_gene2469 1.44e-17 87.4 COG0145@1|root,COG0146@1|root,COG0145@2|Bacteria,COG0146@2|Bacteria,1MU2Y@1224|Proteobacteria,2TQZ6@28211|Alphaproteobacteria 28211|Alphaproteobacteria EQ N-methylhydantoinase A acetone carboxylase, beta subunit - - 3.5.2.14,3.5.2.9 ko:K01469,ko:K01473 ko00330,ko00480,ko01100,map00330,map00480,map01100 - R00251,R03187 RC00553,RC00632 ko00000,ko00001,ko01000 - - - Hydant_A_N,Hydantoinase_A,Hydantoinase_B k141_294_1 998674.ATTE01000001_gene1546 7.44e-24 100.0 COG2738@1|root,COG2738@2|Bacteria,1RDJH@1224|Proteobacteria,1S4QY@1236|Gammaproteobacteria,461SZ@72273|Thiotrichales 72273|Thiotrichales S Putative neutral zinc metallopeptidase - - - ko:K06973 - - - - ko00000 - - - Zn_peptidase_2 k141_337_1 1167006.UWK_02617 1.74e-10 61.6 COG0471@1|root,COG0471@2|Bacteria,1MU0K@1224|Proteobacteria,42MR7@68525|delta/epsilon subdivisions,2WIKA@28221|Deltaproteobacteria,2MHKE@213118|Desulfobacterales 28221|Deltaproteobacteria P Citrate transporter - - - - - - - - - - - - CitMHS,TrkA_C k141_337_2 1121875.KB907561_gene523 1.76e-36 130.0 COG0607@1|root,COG0607@2|Bacteria 2|Bacteria P Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - - - - - - - - - - Rhodanese k141_382_1 396588.Tgr7_0499 2.15e-80 258.0 COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,1RPCU@1236|Gammaproteobacteria,1WWF4@135613|Chromatiales 135613|Chromatiales S ABC transporter - - - ko:K15738 - - - - ko00000,ko02000 3.A.1.120.6 - - ABC_tran,ABC_tran_CTD,ABC_tran_Xtn k141_516_1 1463861.JNXE01000001_gene5443 2.45e-42 155.0 COG1804@1|root,COG1804@2|Bacteria,2GKDI@201174|Actinobacteria 201174|Actinobacteria C L-carnitine dehydratase bile acid-inducible protein F - - - - - - - - - - - - CoA_transf_3 k141_249_1 768671.ThimaDRAFT_2471 5.25e-98 296.0 COG0517@1|root,COG0517@2|Bacteria,1MXI6@1224|Proteobacteria,1RYPY@1236|Gammaproteobacteria,1X08U@135613|Chromatiales 135613|Chromatiales S Transposase zinc-binding domain - - - - - - - - - - - - Y2_Tnp,Zn_Tnp_IS91 k141_338_1 713586.KB900536_gene2729 1.41e-55 185.0 COG0489@1|root,COG0489@2|Bacteria,1MU7R@1224|Proteobacteria,1RMJF@1236|Gammaproteobacteria,1WX3A@135613|Chromatiales 135613|Chromatiales D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP - - - ko:K03593 - - - - ko00000,ko03029,ko03036 - - - FeS_assembly_P,ParA k141_295_1 203122.Sde_2907 1.34e-38 148.0 COG1752@1|root,COG1752@2|Bacteria,1Q82E@1224|Proteobacteria,1RRUE@1236|Gammaproteobacteria,46B04@72275|Alteromonadaceae 1236|Gammaproteobacteria S Patatin-like phospholipase - - - - - - - - - - - - Patatin k141_29_1 870187.Thini_3414 2.15e-60 201.0 COG0541@1|root,COG0541@2|Bacteria,1MVIA@1224|Proteobacteria,1RMU9@1236|Gammaproteobacteria,46021@72273|Thiotrichales 72273|Thiotrichales U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components ffh - 3.6.5.4 ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko01000,ko02044 3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9 - - SRP54,SRP54_N,SRP_SPB k141_29_2 1282665.H353_07528 6.8e-08 50.4 COG0228@1|root,COG0228@2|Bacteria,1VA0X@1239|Firmicutes,4HKNN@91061|Bacilli 91061|Bacilli J Belongs to the bacterial ribosomal protein bS16 family rpsP GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02959 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011,ko03029 - - - Ribosomal_S16 k141_118_1 318167.Sfri_1678 5.45e-68 233.0 COG0740@1|root,COG0740@2|Bacteria,1MUQ9@1224|Proteobacteria,1RRQA@1236|Gammaproteobacteria,2QCXZ@267890|Shewanellaceae 1236|Gammaproteobacteria OU Clp protease - - - - - - - - - - - - CLP_protease,Mu-like_gpT k141_296_1 1408424.JHYI01000050_gene2958 8.67e-12 60.1 2EG3W@1|root,339VW@2|Bacteria,1TYC4@1239|Firmicutes,4IMIB@91061|Bacilli,1ZK7W@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - k141_250_1 391937.NA2_03092 1.72e-08 55.8 2DNS7@1|root,32YWC@2|Bacteria,1PT26@1224|Proteobacteria,2UT2J@28211|Alphaproteobacteria,43Q08@69277|Phyllobacteriaceae 28211|Alphaproteobacteria J 23S rRNA-intervening sequence protein - - - - - - - - - - - - 23S_rRNA_IVP k141_206_1 1255043.TVNIR_1251 2.08e-114 357.0 COG3385@1|root,COG3385@2|Bacteria,1MXYG@1224|Proteobacteria,1S0CA@1236|Gammaproteobacteria,1WXQT@135613|Chromatiales 135613|Chromatiales L Transposase IS4 family - - - - - - - - - - - - DDE_Tnp_1,DUF4338,Dimer_Tnp_Tn5,Tnp_DNA_bind k141_30_1 159749.K0RGG6 4.04e-120 350.0 2CNIT@1|root,2QWJF@2759|Eukaryota 2759|Eukaryota C photosynthetic electron transport in photosystem II psbD GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009536,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 1.10.3.9 ko:K02706 ko00195,ko01100,map00195,map01100 M00161 - - ko00000,ko00001,ko00002,ko00194,ko01000 - - - PSII,Photo_RC k141_165_1 312309.VF_1070 1.21e-20 97.4 COG5361@1|root,COG5361@2|Bacteria,1NX2A@1224|Proteobacteria,1SM5A@1236|Gammaproteobacteria,1XVNU@135623|Vibrionales 135623|Vibrionales S Protein of unknown function (DUF1214) - - - - - - - - - - - - DUF1214,DUF1254 k141_471_1 977880.RALTA_A1870 8.55e-67 226.0 COG0567@1|root,COG0567@2|Bacteria,1MVBF@1224|Proteobacteria,2VJ0G@28216|Betaproteobacteria,1K532@119060|Burkholderiaceae 28216|Betaproteobacteria C Dehydrogenase E1 component sucA - 1.2.4.2 ko:K00164 ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00032 R00621,R01933,R01940,R03316,R08549 RC00004,RC00027,RC00627,RC02743,RC02833,RC02883 br01601,ko00000,ko00001,ko00002,ko01000 - - - 2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr k141_297_1 765914.ThisiDRAFT_0456 1.07e-37 132.0 COG0634@1|root,COG0634@2|Bacteria,1NRT8@1224|Proteobacteria,1RNPQ@1236|Gammaproteobacteria,1WWQX@135613|Chromatiales 135613|Chromatiales F phosphoribosyltransferase - - 2.4.2.8 ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 - R00190,R01132,R01229,R02142,R08237,R08238,R08245 RC00063,RC00122 ko00000,ko00001,ko01000 - - - Pribosyltran k141_297_2 926569.ANT_11390 6.44e-11 62.8 COG0005@1|root,COG0005@2|Bacteria,2G5JP@200795|Chloroflexi 200795|Chloroflexi F Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates mtnP - 2.4.2.28 ko:K00772 ko00270,ko01100,map00270,map01100 M00034 R01402 RC00063,RC02819 ko00000,ko00001,ko00002,ko01000 - - - PNP_UDP_1 k141_518_1 713587.THITH_14070 1.08e-56 196.0 COG0058@1|root,COG0058@2|Bacteria,1MW4J@1224|Proteobacteria,1RN8P@1236|Gammaproteobacteria,1WWIV@135613|Chromatiales 135613|Chromatiales G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties - - 2.4.1.1 ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 - R02111 - ko00000,ko00001,ko01000 - GT35 - Phosphorylase k141_518_2 713587.THITH_14070 1.68e-52 183.0 COG0058@1|root,COG0058@2|Bacteria,1MW4J@1224|Proteobacteria,1RN8P@1236|Gammaproteobacteria,1WWIV@135613|Chromatiales 135613|Chromatiales G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties - - 2.4.1.1 ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 - R02111 - ko00000,ko00001,ko01000 - GT35 - Phosphorylase k141_385_1 2340.JV46_16190 1.21e-125 367.0 COG0050@1|root,COG0050@2|Bacteria,1MVC0@1224|Proteobacteria,1RMYX@1236|Gammaproteobacteria,1J5DE@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis tuf GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - ko:K02358 - - - - ko00000,ko03012,ko03029,ko04147 - - - GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 k141_119_2 234267.Acid_1623 7.65e-102 307.0 COG2801@1|root,COG2801@2|Bacteria,3Y821@57723|Acidobacteria 57723|Acidobacteria L Integrase core domain - - - - - - - - - - - - rve_3 k141_251_1 565045.NOR51B_400 4.33e-34 130.0 COG5361@1|root,COG5361@2|Bacteria,1NBVB@1224|Proteobacteria,1SES6@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Neurotransmitter-gated ion-channel ligand binding domain - - - - - - - - - - - - Neur_chan_LBD,Neur_chan_memb k141_298_1 411464.DESPIG_02142 9.21e-44 162.0 COG1882@1|root,COG1882@2|Bacteria,1MWBF@1224|Proteobacteria,42M5J@68525|delta/epsilon subdivisions,2WJAK@28221|Deltaproteobacteria,2M9FS@213115|Desulfovibrionales 28221|Deltaproteobacteria C Glycine radical - - 2.3.1.54,4.1.99.11 ko:K00656,ko:K07540 ko00620,ko00623,ko00640,ko00650,ko01100,ko01120,ko01220,map00620,map00623,map00640,map00650,map01100,map01120,map01220 M00418 R00212,R05598,R06987 RC00004,RC01181,RC01433,RC01434,RC02742,RC02833 ko00000,ko00001,ko00002,ko01000 - - - Gly_radical,PFL-like k141_519_1 686340.Metal_1505 4.05e-25 108.0 COG2931@1|root,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,1RNK8@1236|Gammaproteobacteria,1XFUS@135618|Methylococcales 135618|Methylococcales QU COG2931 RTX toxins and related Ca2 -binding proteins - - - - - - - - - - - - DUF4347 k141_386_1 335543.Sfum_2600 2.39e-37 137.0 COG3547@1|root,COG3547@2|Bacteria,1NGR7@1224|Proteobacteria,42NNQ@68525|delta/epsilon subdivisions,2WM2H@28221|Deltaproteobacteria,2MSJJ@213462|Syntrophobacterales 28221|Deltaproteobacteria L PFAM transposase IS116 IS110 IS902 family protein - - - - - - - - - - - - DEDD_Tnp_IS110,Transposase_20 k141_120_1 565045.NOR51B_2884 4.24e-35 135.0 COG2303@1|root,COG2303@2|Bacteria,1P9UF@1224|Proteobacteria,1RPS8@1236|Gammaproteobacteria,1J966@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria E COG2303 Choline dehydrogenase and related flavoproteins - - - - - - - - - - - - GMC_oxred_C,GMC_oxred_N k141_167_1 96561.Dole_0177 2.18e-34 132.0 COG1600@1|root,COG1600@2|Bacteria 2|Bacteria C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) - - - - - - - - - - - - - k141_558_1 556268.OFAG_00122 4.27e-32 117.0 COG0242@1|root,COG0242@2|Bacteria,1R9XK@1224|Proteobacteria,2VQ0U@28216|Betaproteobacteria,472J5@75682|Oxalobacteraceae 28216|Betaproteobacteria J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions def2 - 3.5.1.88 ko:K01462 - - - - ko00000,ko01000 - - - Pep_deformylase k141_299_1 645512.GCWU000246_01691 2.57e-21 95.9 COG0568@1|root,COG0568@2|Bacteria,3TACS@508458|Synergistetes 508458|Synergistetes K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth sigA - - ko:K03086 - - - - ko00000,ko03021 - - - Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4 k141_252_1 644282.Deba_2841 2.45e-73 224.0 COG0437@1|root,COG0437@2|Bacteria,1MU5T@1224|Proteobacteria,42R9D@68525|delta/epsilon subdivisions,2WN5Q@28221|Deltaproteobacteria 28221|Deltaproteobacteria C PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - - - - - - - - - - Fer4_11,Fer4_4,Fer4_7 k141_252_2 644282.Deba_2842 7.55e-20 89.0 COG0243@1|root,COG0243@2|Bacteria,1P01N@1224|Proteobacteria,42M9D@68525|delta/epsilon subdivisions,2WJ43@28221|Deltaproteobacteria 28221|Deltaproteobacteria C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - 1.8.5.5 ko:K08352 ko00920,ko01120,map00920,map01120 - R10149 RC02823 ko00000,ko00001,ko01000,ko02000 5.A.3.5 - - Molybdop_Fe4S4,Molybdopterin,Molydop_binding k141_209_1 323261.Noc_2921 1.05e-47 169.0 COG0459@1|root,COG0459@2|Bacteria,1MURR@1224|Proteobacteria,1RMTB@1236|Gammaproteobacteria,1WWXH@135613|Chromatiales 135613|Chromatiales O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions groL - - ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 - - - ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 - - - Cpn60_TCP1 k141_34_1 2340.JV46_14180 3.22e-16 81.3 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1J56I@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria T (GGDEF) domain - - 3.1.4.52 ko:K21024 ko02025,map02025 - - - ko00000,ko00001,ko01000 - - - EAL,GGDEF,PAS,PAS_3,PAS_9,SBP_bac_3 k141_253_1 1499967.BAYZ01000039_gene2213 1.5e-81 256.0 COG1502@1|root,COG1502@2|Bacteria 2|Bacteria I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol - - - - - - - - - - - - Helicase_C,PLDc_2,ResIII,SNF2_N k141_560_1 1121875.KB907549_gene2005 1.99e-94 299.0 COG1882@1|root,COG1882@2|Bacteria,4NDWW@976|Bacteroidetes,1I0UR@117743|Flavobacteriia 976|Bacteroidetes C Pyruvate formate lyase-like - - 2.3.1.54,4.1.1.83 ko:K00656,ko:K18427 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 - R00212,R06987 RC00004,RC01181,RC02742,RC02833 ko00000,ko00001,ko01000 - - - Gly_radical,PFL-like k141_344_1 1121875.KB907549_gene2005 1.6e-84 274.0 COG1882@1|root,COG1882@2|Bacteria,4NDWW@976|Bacteroidetes,1I0UR@117743|Flavobacteriia 976|Bacteroidetes C Pyruvate formate lyase-like - - 2.3.1.54,4.1.1.83 ko:K00656,ko:K18427 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 - R00212,R06987 RC00004,RC01181,RC02742,RC02833 ko00000,ko00001,ko01000 - - - Gly_radical,PFL-like k141_523_1 1121875.KB907549_gene2005 1.17e-102 321.0 COG1882@1|root,COG1882@2|Bacteria,4NDWW@976|Bacteroidetes,1I0UR@117743|Flavobacteriia 976|Bacteroidetes C Pyruvate formate lyase-like - - 2.3.1.54,4.1.1.83 ko:K00656,ko:K18427 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 - R00212,R06987 RC00004,RC01181,RC02742,RC02833 ko00000,ko00001,ko01000 - - - Gly_radical,PFL-like k141_561_1 1298867.AUES01000126_gene5138 1.85e-69 221.0 COG0517@1|root,COG0517@2|Bacteria,1MXI6@1224|Proteobacteria,2TS6X@28211|Alphaproteobacteria,3JWIG@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Putative transposase - - - - - - - - - - - - Y2_Tnp,Zn_Tnp_IS91 k141_561_2 1366050.N234_36435 5.11e-33 122.0 COG4974@1|root,COG4974@2|Bacteria,1MVAN@1224|Proteobacteria,2VNSH@28216|Betaproteobacteria,1KGQD@119060|Burkholderiaceae 28216|Betaproteobacteria L Phage integrase, N-terminal SAM-like domain - - - ko:K04763 - - - - ko00000,ko03036 - - - Phage_int_SAM_4,Phage_integrase k141_169_1 1517681.HW45_09695 6.48e-58 198.0 COG1524@1|root,COG1524@2|Bacteria,1R5V5@1224|Proteobacteria,1S06C@1236|Gammaproteobacteria,1XUEX@135623|Vibrionales 135623|Vibrionales S Type I phosphodiesterase / nucleotide pyrophosphatase - - - - - - - - - - - - Phosphodiest k141_390_1 314278.NB231_09623 3.97e-113 337.0 COG0399@1|root,COG0399@2|Bacteria,1MUMJ@1224|Proteobacteria,1T3U5@1236|Gammaproteobacteria,1X1MF@135613|Chromatiales 135613|Chromatiales M Putative transposase - - - - - - - - - - - - Y2_Tnp k141_438_1 501479.ACNW01000062_gene2740 8.19e-79 253.0 28HMZ@1|root,2Z7WD@2|Bacteria,1MU3Q@1224|Proteobacteria,2TSGX@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Protein of unknown function (DUF3604) - - - - - - - - - - - - DUF3604 k141_345_1 10658.DPOL_BPPRD 2.16e-21 100.0 4QAWD@10239|Viruses,4QVNG@35237|dsDNA viruses no RNA stage,4QHTW@10656|Tectiviridae 10656|Tectiviridae L DNA binding - GO:0003674,GO:0003824,GO:0003887,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576 - - - - - - - - - - - k141_524_1 1382306.JNIM01000001_gene3555 5.58e-79 263.0 COG0086@1|root,COG0086@2|Bacteria,2G632@200795|Chloroflexi 200795|Chloroflexi K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates rpoC GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5 k141_170_1 1121033.AUCF01000008_gene5661 5.71e-46 157.0 COG0664@1|root,COG0664@2|Bacteria,1R6BV@1224|Proteobacteria,2TU8X@28211|Alphaproteobacteria,2JS1G@204441|Rhodospirillales 204441|Rhodospirillales K Cyclic nucleotide-monophosphate binding domain - - - ko:K01420 - - - - ko00000,ko03000 - - - HTH_Crp_2,cNMP_binding k141_170_2 314278.NB231_15313 2.18e-11 62.8 COG0741@1|root,COG0741@2|Bacteria,1R666@1224|Proteobacteria,1S3XT@1236|Gammaproteobacteria,1X0S8@135613|Chromatiales 135613|Chromatiales M PFAM Lytic transglycosylase catalytic - - - - - - - - - - - - SLT k141_525_1 566466.NOR53_601 9.74e-102 323.0 COG4447@1|root,COG4447@2|Bacteria,1MVIT@1224|Proteobacteria,1RZK1@1236|Gammaproteobacteria,1J9EJ@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S Sortilin, neurotensin receptor 3, - - - - - - - - - - - - Sortilin-Vps10 k141_38_1 411460.RUMTOR_02902 6.17e-11 63.5 2DPDN@1|root,331NP@2|Bacteria,1VFF8@1239|Firmicutes,24S9D@186801|Clostridia 186801|Clostridia S ORF located using Blastx - - - - - - - - - - - - - k141_127_1 1215114.BBIU01000004_gene431 2.45e-35 130.0 COG1250@1|root,COG1250@2|Bacteria,1MV8M@1224|Proteobacteria,1RSQP@1236|Gammaproteobacteria 1236|Gammaproteobacteria C Catalyzes the NAD( )-dependent oxidation of L-carnitine to 3-dehydrocarnitine - - - - - - - - - - - - 3HCDH,3HCDH_N k141_172_1 2340.JV46_22460 0.000466 41.6 COG1760@1|root,COG1760@2|Bacteria,1MUZN@1224|Proteobacteria,1RMJZ@1236|Gammaproteobacteria,1J51J@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria E COG1760 L-serine deaminase - - 4.3.1.17 ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 - R00220,R00590 RC00331,RC02600 ko00000,ko00001,ko01000 - - - SDH_alpha,SDH_beta k141_172_2 1229204.AMYY01000019_gene425 1.01e-22 94.4 COG2166@1|root,COG2166@2|Bacteria,1RI8F@1224|Proteobacteria 1224|Proteobacteria S Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process sufE GO:0003674,GO:0006464,GO:0006790,GO:0006807,GO:0006950,GO:0006979,GO:0008047,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0019538,GO:0022607,GO:0030234,GO:0031162,GO:0031163,GO:0036211,GO:0043085,GO:0043170,GO:0043412,GO:0044085,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050790,GO:0050896,GO:0065007,GO:0065009,GO:0071704,GO:0071840,GO:0097163,GO:0098772,GO:0140104,GO:1901564 - ko:K02426 - - - - ko00000 - - iSBO_1134.SBO_1451,iSFV_1184.SFV_1702,iSF_1195.SF1708,iSFxv_1172.SFxv_1916,iS_1188.S1841,iSbBS512_1146.SbBS512_E1880 SufE k141_526_2 196367.JNFG01000034_gene7502 1.22e-29 114.0 COG3391@1|root,COG3391@2|Bacteria,1RERQ@1224|Proteobacteria,2WH2J@28216|Betaproteobacteria,1KIH2@119060|Burkholderiaceae 28216|Betaproteobacteria S Low-density lipoprotein-receptor YWTD domain - - - - - - - - - - - - - k141_81_1 1449976.KALB_3084 9.95e-14 76.6 COG1574@1|root,COG1574@2|Bacteria,2GJVW@201174|Actinobacteria,4E1CM@85010|Pseudonocardiales 201174|Actinobacteria S Amidohydrolase family - - - - - - - - - - - - Amidohydro_3 k141_40_1 449447.MAE_25760 8.49e-34 119.0 COG4680@1|root,COG4680@2|Bacteria,1G7BW@1117|Cyanobacteria 1117|Cyanobacteria S protein conserved in bacteria - - - ko:K19166 - - - - ko00000,ko01000,ko02048 - - - HigB_toxin k141_128_1 497964.CfE428DRAFT_1133 1.82e-35 132.0 COG0385@1|root,COG0385@2|Bacteria,46U6P@74201|Verrucomicrobia 74201|Verrucomicrobia S Sodium Bile acid symporter family - - - - - - - - - - - - SBF k141_349_1 1278307.KB906996_gene3004 2.66e-87 271.0 COG1600@1|root,COG1600@2|Bacteria,1N0WQ@1224|Proteobacteria 1224|Proteobacteria C dehalogenase - - 1.21.99.5 ko:K21647 ko00625,ko01100,ko01120,map00625,map01100,map01120 - R05499,R05500,R05501 RC00268,RC01398 ko00000,ko00001,ko01000 - - - Dehalogenase,Fer4_16 k141_482_1 2342.SOPEG_2124 1.38e-08 58.5 COG0795@1|root,COG0795@2|Bacteria,1MUF2@1224|Proteobacteria,1RMN5@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Permease lptF GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015221,GO:0015399,GO:0015405,GO:0015437,GO:0015920,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0032991,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043190,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1901264,GO:1901505,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - ko:K07091 ko02010,map02010 M00320 - - ko00000,ko00001,ko00002,ko02000 1.B.42.1 - iECED1_1282.ECED1_5114,iUMNK88_1353.UMNK88_5207 YjgP_YjgQ k141_41_1 768671.ThimaDRAFT_4428 5.02e-49 167.0 COG3547@1|root,COG3547@2|Bacteria,1NGR7@1224|Proteobacteria,1RMF9@1236|Gammaproteobacteria,1WZPM@135613|Chromatiales 135613|Chromatiales L Transposase IS116/IS110/IS902 family - - - - - - - - - - - - DEDD_Tnp_IS110,Transposase_20 k141_129_1 1397527.Q670_06625 4.78e-54 180.0 COG1702@1|root,COG1702@2|Bacteria,1MVDV@1224|Proteobacteria,1RP2Y@1236|Gammaproteobacteria,1XID6@135619|Oceanospirillales 135619|Oceanospirillales T Phosphate starvation-inducible protein PhoH phoH - - ko:K06217 - - - - ko00000 - - - PhoH k141_527_1 247633.GP2143_14751 3.11e-95 281.0 COG0231@1|root,COG0231@2|Bacteria,1MW2J@1224|Proteobacteria,1RPW7@1236|Gammaproteobacteria,1J4HC@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria J Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-34 is required for alleviation efp GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006414,GO:0006417,GO:0006448,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0017148,GO:0019222,GO:0019538,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0045900,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0071704,GO:0072344,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2000112,GO:2000113,GO:2001124,GO:2001125 - ko:K02356 - - - - ko00000,ko03012 - - - EFP,EFP_N,Elong-fact-P_C k141_527_2 494416.AYXN01000030_gene2037 1.19e-13 71.2 COG1509@1|root,COG1509@2|Bacteria,1MUPJ@1224|Proteobacteria,1RM84@1236|Gammaproteobacteria,3NJDI@468|Moraxellaceae 1236|Gammaproteobacteria C 4Fe-4S single cluster domain epmB GO:0003674,GO:0003824,GO:0005488,GO:0016853,GO:0016866,GO:0016869,GO:0048037,GO:0051536,GO:0051539,GO:0051540 5.4.3.2 ko:K01843,ko:K19810 ko00310,map00310 - R00461 RC00303 ko00000,ko00001,ko01000,ko03012 - - iECH74115_1262.ECH74115_5662,iECIAI39_1322.ECIAI39_4611,iS_1188.S4569 Fer4_12,Fer4_14,Radical_SAM k141_351_1 686578.AFFX01000001_gene1047 1.39e-45 165.0 COG1766@1|root,COG1766@2|Bacteria,1MUQR@1224|Proteobacteria,1RN6T@1236|Gammaproteobacteria 1236|Gammaproteobacteria N The M ring may be actively involved in energy transduction fliF - - ko:K02409 ko02040,map02040 - - - ko00000,ko00001,ko02035,ko02044 3.A.6.2,3.A.6.3 - - YscJ_FliF,YscJ_FliF_C k141_87_1 313603.FB2170_16831 1.05e-06 49.7 COG1082@1|root,COG1082@2|Bacteria,4NKFY@976|Bacteroidetes,1I3V7@117743|Flavobacteriia 976|Bacteroidetes G Xylose isomerase-like TIM barrel - - - - - - - - - - - - AP_endonuc_2 k141_87_2 387631.Asulf_01565 2.67e-31 115.0 COG1853@1|root,arCOG02017@2157|Archaea,2XXVW@28890|Euryarchaeota,24720@183980|Archaeoglobi 183980|Archaeoglobi S Flavin reductase like domain - - 1.16.1.10 ko:K18915 - - - - ko00000,ko01000 - - - Flavin_Reduct k141_305_2 416269.APL_0509 2.57e-93 300.0 COG5511@1|root,COG5511@2|Bacteria,1MVN4@1224|Proteobacteria,1RRK4@1236|Gammaproteobacteria,1Y7IC@135625|Pasteurellales 135625|Pasteurellales S Bacteriophage capsid protein - - - - - - - - - - - - Phage_portal_2 k141_305_3 936573.HMPREF1147_1716 6.76e-05 44.3 2FCAH@1|root,344E5@2|Bacteria,1W0GH@1239|Firmicutes,4H858@909932|Negativicutes 909932|Negativicutes - - - - - - - - - - - - - - - k141_305_4 657322.FPR_26880 6.8e-139 424.0 COG5525@1|root,COG5525@2|Bacteria,1TQBY@1239|Firmicutes,248DP@186801|Clostridia,3WGMP@541000|Ruminococcaceae 186801|Clostridia S Phage terminase large subunit (GpA) - - - - - - - - - - - - Terminase_GpA k141_306_1 522306.CAP2UW1_3683 1.38e-36 136.0 COG5433@1|root,COG5433@2|Bacteria,1MXI8@1224|Proteobacteria,2W66H@28216|Betaproteobacteria 28216|Betaproteobacteria L PFAM Transposase, IS4-like - - - - - - - - - - - - - k141_306_2 522306.CAP2UW1_3683 1.61e-34 129.0 COG5433@1|root,COG5433@2|Bacteria,1MXI8@1224|Proteobacteria,2W66H@28216|Betaproteobacteria 28216|Betaproteobacteria L PFAM Transposase, IS4-like - - - - - - - - - - - - - k141_583_1 580332.Slit_1617 8.58e-56 191.0 COG0374@1|root,COG0374@2|Bacteria,1MWFJ@1224|Proteobacteria,2VJ52@28216|Betaproteobacteria 28216|Betaproteobacteria C Belongs to the NiFe NiFeSe hydrogenase large subunit family - - 1.12.99.6 ko:K06281 ko00633,ko01120,map00633,map01120 - R08034 RC00250 ko00000,ko00001,ko01000 - - - NiFeSe_Hases k141_188_1 1313172.YM304_05290 4.09e-78 240.0 COG2207@1|root,COG2207@2|Bacteria,2GNMI@201174|Actinobacteria 201174|Actinobacteria K transcriptional regulator - - - - - - - - - - - - AraC_N,HTH_18 k141_366_1 1283283.ATXA01000003_gene1560 5.69e-58 190.0 COG3386@1|root,COG3386@2|Bacteria,2GNV1@201174|Actinobacteria,4EUXG@85013|Frankiales 201174|Actinobacteria G SMP-30/Gluconolaconase/LRE-like region - - - ko:K14274 ko00040,map00040 - R02427 RC00713 ko00000,ko00001,ko01000 - - - SGL k141_57_1 1168478.I6R115_9CAUD 1.07e-22 101.0 4QBUC@10239|Viruses,4QVRG@35237|dsDNA viruses no RNA stage,4QQGQ@28883|Caudovirales,4QMEK@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k141_413_1 1196324.A374_14170 1.4e-24 108.0 COG1804@1|root,COG1804@2|Bacteria,1TP54@1239|Firmicutes,4HABI@91061|Bacilli 91061|Bacilli C acyl-CoA transferases carnitine dehydratase - - - - - - - - - - - - CoA_transf_3 k141_323_1 323850.Shew_0809 4.93e-45 166.0 COG0493@1|root,COG3383@1|root,COG0493@2|Bacteria,COG3383@2|Bacteria,1MU2H@1224|Proteobacteria,1SMV9@1236|Gammaproteobacteria,2Q94Z@267890|Shewanellaceae 1236|Gammaproteobacteria C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - 1.17.1.9 ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 - R00519 RC02796 ko00000,ko00001,ko01000 - - - Fer2_4,Fer4,Fer4_20,Fer4_7,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,Pyr_redox_2 k141_500_1 929562.Emtol_2853 2.79e-10 63.2 COG2197@1|root,COG2197@2|Bacteria,4NQSY@976|Bacteroidetes,47QHW@768503|Cytophagia 976|Bacteroidetes KT helix_turn_helix, Lux Regulon - - - - - - - - - - - - GerE k141_147_1 1282361.ABAC402_16960 7.21e-06 54.3 COG2911@1|root,COG2931@1|root,COG2911@2|Bacteria,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,2TRVY@28211|Alphaproteobacteria 28211|Alphaproteobacteria Q COG2931 RTX toxins and related Ca2 -binding proteins - - 3.4.24.40 ko:K01406 ko01503,map01503 - - - ko00000,ko00001,ko01000,ko01002 - - - CBM_6,DUF4214,He_PIG,Peptidase_M10,Peptidase_M10_C k141_368_1 262768.PAM_492 2.9e-21 89.0 2B9ZZ@1|root,323DM@2|Bacteria,3WUUY@544448|Tenericutes 544448|Tenericutes S COG NOG15344 non supervised orthologous group - - - - - - - - - - - - - k141_585_1 1280001.BAOA01000031_gene5175 1.47e-60 211.0 COG2911@1|root,COG2931@1|root,COG2911@2|Bacteria,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,1RNK8@1236|Gammaproteobacteria 1236|Gammaproteobacteria Q COG2931 RTX toxins and related Ca2 -binding proteins - - - - - - - - - - - - Cadherin_3,Calx-beta,He_PIG,OmpA_membrane,VWA_2,fn3 k141_501_1 1121106.JQKB01000018_gene4929 9.86e-24 99.4 COG2080@1|root,COG2080@2|Bacteria,1RB3F@1224|Proteobacteria,2VF0C@28211|Alphaproteobacteria,2JRTI@204441|Rhodospirillales 204441|Rhodospirillales C [2Fe-2S] binding domain - - - - - - - - - - - - Fer2,Fer2_2 k141_538_1 1123257.AUFV01000017_gene3736 3.45e-38 138.0 COG4582@1|root,COG4582@2|Bacteria,1MW69@1224|Proteobacteria,1RNPD@1236|Gammaproteobacteria,1X5Y2@135614|Xanthomonadales 135614|Xanthomonadales D Cell division protein - - - - - - - - - - - - ZapD k141_324_1 1232410.KI421425_gene1550 3.74e-61 206.0 COG0457@1|root,COG0457@2|Bacteria,1MXSS@1224|Proteobacteria,42Z0Q@68525|delta/epsilon subdivisions,2WU0G@28221|Deltaproteobacteria,43T6R@69541|Desulfuromonadales 28221|Deltaproteobacteria S Tetratricopeptide repeat - - - - - - - - - - - - - k141_456_1 1255043.TVNIR_0754 1.93e-52 185.0 COG3385@1|root,COG3385@2|Bacteria,1MXYG@1224|Proteobacteria,1S0CA@1236|Gammaproteobacteria,1WXQT@135613|Chromatiales 135613|Chromatiales L Transposase IS4 family - - - - - - - - - - - - DDE_Tnp_1,DUF4338,Dimer_Tnp_Tn5,Tnp_DNA_bind k141_369_1 1397528.Q671_08630 4.4e-93 286.0 COG3344@1|root,COG3344@2|Bacteria,1MVI1@1224|Proteobacteria,1RQP7@1236|Gammaproteobacteria,1XNSE@135619|Oceanospirillales 135619|Oceanospirillales L Reverse transcriptase (RNA-dependent DNA polymerase) - - - - - - - - - - - - RVT_1 k141_107_1 1231391.AMZF01000036_gene2992 3.76e-32 122.0 COG0418@1|root,COG0418@2|Bacteria,1MUYP@1224|Proteobacteria,2VH6F@28216|Betaproteobacteria,3T2E6@506|Alcaligenaceae 28216|Betaproteobacteria F Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate pyrC - 3.5.2.3 ko:K01465 ko00240,ko01100,map00240,map01100 M00051 R01993 RC00632 ko00000,ko00001,ko00002,ko01000 - - - Amidohydro_1 k141_283_1 498761.HM1_2438 2.03e-21 96.7 COG0484@1|root,COG0484@2|Bacteria,1TP00@1239|Firmicutes,248EM@186801|Clostridia 186801|Clostridia O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins dnaJ - - ko:K03686 - - - - ko00000,ko03029,ko03110 - - - DnaJ,DnaJ_C,DnaJ_CXXCXGXG k141_238_1 1026882.MAMP_01504 2.46e-09 63.2 COG1570@1|root,COG1570@2|Bacteria,1MUA4@1224|Proteobacteria,1RNAZ@1236|Gammaproteobacteria,460FW@72273|Thiotrichales 72273|Thiotrichales L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides xseA - 3.1.11.6 ko:K03601 ko03430,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - Exonuc_VII_L,tRNA_anti_2 k141_588_1 1116472.MGMO_3c00040 1.35e-36 134.0 COG3344@1|root,COG3344@2|Bacteria,1MVI1@1224|Proteobacteria,1RQP7@1236|Gammaproteobacteria,1XFDE@135618|Methylococcales 135618|Methylococcales L PFAM RNA-directed DNA polymerase (reverse transcriptase) - - - - - - - - - - - - GIIM,RVT_1 k141_108_1 765913.ThidrDRAFT_1847 3.42e-43 151.0 COG0577@1|root,COG0577@2|Bacteria,1MVN1@1224|Proteobacteria,1RNVN@1236|Gammaproteobacteria,1WXQU@135613|Chromatiales 135613|Chromatiales V MacB-like periplasmic core domain - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD k141_108_2 765912.Thimo_2507 3.73e-54 175.0 COG1136@1|root,COG1136@2|Bacteria,1RA1K@1224|Proteobacteria,1S275@1236|Gammaproteobacteria,1WWZ2@135613|Chromatiales 135613|Chromatiales V pfam abc - - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran k141_284_1 1047013.AQSP01000122_gene2249 8.39e-90 281.0 28NDD@1|root,2ZBG6@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - DDE_Tnp_1 k141_504_2 270374.MELB17_01265 6.14e-28 114.0 COG4584@1|root,COG4584@2|Bacteria,1MWIV@1224|Proteobacteria,1RQ9W@1236|Gammaproteobacteria,468AQ@72275|Alteromonadaceae 1236|Gammaproteobacteria L COG4584 Transposase and inactivated derivatives - - - - - - - - - - - - HTH_23,rve k141_19_1 384676.PSEEN1869 8.01e-103 310.0 COG1219@1|root,COG1219@2|Bacteria,1MVQK@1224|Proteobacteria,1RN9N@1236|Gammaproteobacteria 1236|Gammaproteobacteria O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP clpX GO:0000166,GO:0000502,GO:0002020,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009376,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0019899,GO:0019904,GO:0030163,GO:0030164,GO:0030554,GO:0031597,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043335,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051301,GO:0051704,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0097718,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1904949,GO:1905368,GO:1905369 - ko:K03544 ko04112,map04112 - - - ko00000,ko00001,ko03110 - - - AAA_2,ClpB_D2-small,zf-C4_ClpX k141_542_1 502025.Hoch_0562 3.27e-25 107.0 COG2006@1|root,COG2006@2|Bacteria,1QMGX@1224|Proteobacteria,42PRJ@68525|delta/epsilon subdivisions,2WMFN@28221|Deltaproteobacteria,2Z073@29|Myxococcales 28221|Deltaproteobacteria S Domain of unknown function (DUF362) - - - - - - - - - - - - DUF362 k141_64_1 1045856.EcWSU1_04131 1.88e-51 165.0 COG0048@1|root,COG0048@2|Bacteria,1RCWY@1224|Proteobacteria,1S3WB@1236|Gammaproteobacteria,3X287@547|Enterobacter 1236|Gammaproteobacteria J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit rpsL GO:0000372,GO:0000375,GO:0000376,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008380,GO:0009058,GO:0009059,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010604,GO:0010628,GO:0015935,GO:0016070,GO:0019219,GO:0019222,GO:0019538,GO:0019843,GO:0022626,GO:0022627,GO:0031323,GO:0031325,GO:0032991,GO:0033120,GO:0034336,GO:0034337,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043484,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045935,GO:0046483,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990145,GO:1990904 - ko:K02950 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosom_S12_S23 k141_459_1 367336.OM2255_06000 6.96e-114 335.0 COG4663@1|root,COG4663@2|Bacteria,1MUXI@1224|Proteobacteria,2TQVW@28211|Alphaproteobacteria 28211|Alphaproteobacteria Q Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - - - - - - - - - - DctP k141_240_1 717774.Marme_1747 1.35e-09 58.2 COG0501@1|root,COG0501@2|Bacteria,1MUNA@1224|Proteobacteria,1RMZ6@1236|Gammaproteobacteria,1XIXM@135619|Oceanospirillales 135619|Oceanospirillales O peptidase - - - - - - - - - - - - Peptidase_M48 k141_285_1 1255043.TVNIR_0754 7.05e-49 176.0 COG3385@1|root,COG3385@2|Bacteria,1MXYG@1224|Proteobacteria,1S0CA@1236|Gammaproteobacteria,1WXQT@135613|Chromatiales 135613|Chromatiales L Transposase IS4 family - - - - - - - - - - - - DDE_Tnp_1,DUF4338,Dimer_Tnp_Tn5,Tnp_DNA_bind k141_241_1 1243664.CAVL020000041_gene3929 3.72e-35 132.0 COG2801@1|root,COG2801@2|Bacteria,1UYSY@1239|Firmicutes,4HTKB@91061|Bacilli 91061|Bacilli L Integrase core domain - - - - - - - - - - - - rve k141_460_1 1286631.X805_01340 2.55e-05 52.4 COG0745@1|root,COG0745@2|Bacteria,1NDDT@1224|Proteobacteria,2VX06@28216|Betaproteobacteria,1KNSG@119065|unclassified Burkholderiales 28216|Betaproteobacteria K Transcriptional regulatory protein, C terminal - - - ko:K07657 ko02020,map02020 M00434 - - ko00000,ko00001,ko00002,ko02022 - - - Trans_reg_C k141_21_1 396595.TK90_0985 7.52e-79 256.0 COG0659@1|root,COG0659@2|Bacteria,1MWDF@1224|Proteobacteria,1SYC8@1236|Gammaproteobacteria,1WXY0@135613|Chromatiales 135613|Chromatiales P Sulfate transporter antisigma-factor antagonist STAS - - - - - - - - - - - - STAS,Sulfate_transp k141_111_1 517418.Ctha_0930 2.59e-52 176.0 COG1294@1|root,COG1294@2|Bacteria,1FDE9@1090|Chlorobi 1090|Chlorobi C Cytochrome d ubiquinol oxidase, subunit II - - 1.10.3.14 ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00153 R11325 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.4.3 - - Cyt_bd_oxida_II k141_421_1 571.MC52_30130 9.61e-23 100.0 COG3385@1|root,COG3385@2|Bacteria,1RBZF@1224|Proteobacteria,1S381@1236|Gammaproteobacteria 1236|Gammaproteobacteria L Transposase DDE domain - - - - - - - - - - - - DDE_Tnp_1 k141_593_1 105559.Nwat_2358 1.76e-29 109.0 COG5573@1|root,COG5573@2|Bacteria,1RKIK@1224|Proteobacteria,1SBYM@1236|Gammaproteobacteria,1X2IA@135613|Chromatiales 135613|Chromatiales S PIN domain - - - - - - - - - - - - PIN k141_593_2 1379270.AUXF01000002_gene1303 1.06e-15 72.4 2DR3J@1|root,33A0M@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k141_546_1 1123517.JOMR01000001_gene1107 6.13e-81 264.0 COG0188@1|root,COG0188@2|Bacteria,1MUGG@1224|Proteobacteria,1RN03@1236|Gammaproteobacteria,45ZYT@72273|Thiotrichales 72273|Thiotrichales L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner gyrA - 5.99.1.3 ko:K02469 - - - - ko00000,ko01000,ko03032,ko03400 - - - DNA_gyraseA_C,DNA_topoisoIV k141_243_1 1313172.YM304_05300 1.17e-103 308.0 COG1028@1|root,COG1028@2|Bacteria,2GIYQ@201174|Actinobacteria 201174|Actinobacteria IQ Belongs to the short-chain dehydrogenases reductases (SDR) family - - - - - - - - - - - - adh_short k141_462_1 111781.Lepto7376_1010 4.15e-43 159.0 COG1262@1|root,COG4249@1|root,COG1262@2|Bacteria,COG4249@2|Bacteria 2|Bacteria S B-1 B cell differentiation - - - - - - - - - - - - FGE-sulfatase,PEGA,Peptidase_C14,TIR_2 k141_332_1 1198232.CYCME_1869 4.43e-159 456.0 COG1883@1|root,COG1883@2|Bacteria,1MV0G@1224|Proteobacteria,1RP3W@1236|Gammaproteobacteria,460AC@72273|Thiotrichales 72273|Thiotrichales C decarboxylase, beta subunit - - 4.1.1.3 ko:K01572 ko00620,ko01100,map00620,map01100 - R00217 RC00040 ko00000,ko00001,ko01000,ko02000 3.B.1.1.1 - - OAD_beta k141_547_1 1121447.JONL01000022_gene3718 1.5e-33 117.0 2B9ZZ@1|root,323DM@2|Bacteria,1MZ6J@1224|Proteobacteria,42WB2@68525|delta/epsilon subdivisions,2WWEJ@28221|Deltaproteobacteria,2MFC3@213115|Desulfovibrionales 28221|Deltaproteobacteria S COG NOG15344 non supervised orthologous group - - - - - - - - - - - - - k141_377_1 357804.Ping_3663 8.82e-46 160.0 2A7JS@1|root,30WHN@2|Bacteria,1PI6M@1224|Proteobacteria,1ST85@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k141_510_1 765912.Thimo_0459 2.72e-113 338.0 COG3344@1|root,COG3344@2|Bacteria,1MVI1@1224|Proteobacteria,1RQP7@1236|Gammaproteobacteria,1WVZP@135613|Chromatiales 135613|Chromatiales L reverse transcriptase - - - - - - - - - - - - RVT_1 k141_463_1 765913.ThidrDRAFT_3979 6.44e-75 234.0 COG1052@1|root,COG1052@2|Bacteria,1MU2D@1224|Proteobacteria,1RPM1@1236|Gammaproteobacteria,1WW4Q@135613|Chromatiales 135613|Chromatiales CH D-isomer specific 2-hydroxyacid dehydrogenase - - 1.1.1.29 ko:K00018 ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200 M00346 R00717,R01388 RC00031,RC00042 ko00000,ko00001,ko00002,ko01000 - - - 2-Hacid_dh,2-Hacid_dh_C k141_423_1 1454004.AW11_02365 5.36e-86 272.0 COG3385@1|root,COG3385@2|Bacteria,1RA6A@1224|Proteobacteria,2VUMQ@28216|Betaproteobacteria 28216|Betaproteobacteria L PFAM Transposase, IS4-like - - - - - - - - - - - - DDE_Tnp_1,DDE_Tnp_1_4 k141_548_1 400668.Mmwyl1_0277 9.5e-56 184.0 COG3547@1|root,COG3547@2|Bacteria,1NGR7@1224|Proteobacteria,1RMF9@1236|Gammaproteobacteria,1XKC6@135619|Oceanospirillales 135619|Oceanospirillales L Transposase - - - - - - - - - - - - DEDD_Tnp_IS110,Transposase_20 k141_115_1 396588.Tgr7_0061 1.33e-22 96.7 COG0661@1|root,COG0661@2|Bacteria,1MU1Z@1224|Proteobacteria,1RNQM@1236|Gammaproteobacteria,1WWEC@135613|Chromatiales 135613|Chromatiales S Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis ubiB - - ko:K03688 - - - - ko00000 - - - ABC1 k141_115_2 227377.CBU_2018 4.62e-11 63.5 COG3165@1|root,COG3165@2|Bacteria,1R1CM@1224|Proteobacteria,1S1SM@1236|Gammaproteobacteria,1JCD7@118969|Legionellales 118969|Legionellales S SCP-2 sterol transfer family - - - ko:K03690 - - - - ko00000 - - - SCP2 k141_333_1 1122225.AULQ01000011_gene131 3.63e-35 137.0 COG1361@1|root,COG2152@1|root,COG1361@2|Bacteria,COG2152@2|Bacteria,4NMB8@976|Bacteroidetes,1HYNW@117743|Flavobacteriia 976|Bacteroidetes M C-terminal domain of CHU protein family - - - - - - - - - - - - CHU_C,DUF11,He_PIG,SdrD_B,SprB k141_158_1 887062.HGR_07521 1.05e-19 91.7 COG1538@1|root,COG1538@2|Bacteria,1MWCJ@1224|Proteobacteria,2VHG1@28216|Betaproteobacteria,4ABVD@80864|Comamonadaceae 28216|Betaproteobacteria MU TIGRFAM type I secretion outer membrane protein, TolC tolC - - ko:K12340 ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133 M00325,M00326,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821 - - ko00000,ko00001,ko00002,ko01504,ko02000,ko02044 1.B.17,2.A.6.2 - - OEP k141_511_1 1179773.BN6_51450 3.35e-50 169.0 COG0500@1|root,COG2226@2|Bacteria,2I35J@201174|Actinobacteria,4E5YH@85010|Pseudonocardiales 201174|Actinobacteria Q Methyltransferase domain - - - - - - - - - - - - Methyltransf_25 ## 207 queries scanned ## Total time (seconds): 37.938536405563354 ## Rate: 5.46 q/s