## Thu Aug 29 14:33:42 2024
## emapper-2.1.12
## /data/home/zhuyingjie/miniforge3/envs/eggnog/bin/emapper.py -i /data/home/zhuyingjie/01_Project/01_metagenome/seagrass/mmseqs_cluster/PRJNA882256/SRR21686226/SRR21686226_p_cluster_rep_seq.fasta --output PRJNA882256_SRR21686226 --data_dir /data/software/eggnog_database -m diamond --sensmode fast --output_dir /data/home/zhuyingjie/01_Project/01_metagenome/seagrass/annotation --temp_dir /data/software/eggnog_database/temp --excel --dbmem --cpu 24
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
k141_3917_1	159749.E7BWK8	1.12e-172	515.0	COG0542@1|root,KOG1051@2759|Eukaryota,2XEW9@2836|Bacillariophyta	2836|Bacillariophyta	O	Belongs to the ClpA ClpB family	-	-	-	-	-	-	-	-	-	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
k141_4546_1	555778.Hneap_0141	1.03e-12	69.7	COG1450@1|root,COG1450@2|Bacteria,1MUUA@1224|Proteobacteria,1RPJS@1236|Gammaproteobacteria,1WWUD@135613|Chromatiales	135613|Chromatiales	NU	general secretion pathway protein D	-	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	Secretin,Secretin_N
k141_4546_2	493475.GARC_0935	1.79e-13	71.2	COG3031@1|root,COG3031@2|Bacteria,1RD3I@1224|Proteobacteria,1RQKA@1236|Gammaproteobacteria,465CV@72275|Alteromonadaceae	1236|Gammaproteobacteria	U	General secretion pathway protein C	gspC	GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705	-	ko:K02452	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	PDZ_2,T2SSC
k141_8208_1	159749.E7BWL6	2.98e-155	453.0	COG0443@1|root,KOG0102@2759|Eukaryota,2XAKJ@2836|Bacillariophyta	2759|Eukaryota	O	heat shock	dnaK	GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005739,GO:0006605,GO:0006810,GO:0006886,GO:0006950,GO:0008104,GO:0008144,GO:0008150,GO:0009266,GO:0009408,GO:0009409,GO:0009507,GO:0009526,GO:0009532,GO:0009536,GO:0009570,GO:0009579,GO:0009628,GO:0009941,GO:0010035,GO:0010038,GO:0015031,GO:0015833,GO:0017076,GO:0030554,GO:0031967,GO:0031975,GO:0032553,GO:0032555,GO:0032559,GO:0033036,GO:0033365,GO:0034613,GO:0035639,GO:0036094,GO:0042221,GO:0042886,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0045036,GO:0045184,GO:0046686,GO:0046907,GO:0048046,GO:0050896,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0070727,GO:0071702,GO:0071705,GO:0072594,GO:0072596,GO:0072598,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	ko:K03283	ko03040,ko04010,ko04141,ko04144,ko04213,ko04612,ko04915,ko05134,ko05145,ko05162,ko05164,ko05169,map03040,map04010,map04141,map04144,map04213,map04612,map04915,map05134,map05145,map05162,map05164,map05169	M00353,M00355	-	-	ko00000,ko00001,ko00002,ko01009,ko03009,ko03029,ko03041,ko03051,ko03110,ko04131,ko04147,ko04516	1.A.33.1	-	-	HSP70
k141_9475_1	1178825.ALIH01000013_gene560	1.21e-29	117.0	COG2755@1|root,COG2755@2|Bacteria,4NGTK@976|Bacteroidetes,1HY1A@117743|Flavobacteriia	976|Bacteroidetes	E	G-D-S-L family lipolytic protein	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL
k141_9475_2	1178825.ALIH01000013_gene561	1.05e-53	186.0	COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,4NDX3@976|Bacteroidetes,1HY9Q@117743|Flavobacteriia	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k141_219_1	330084.JNYZ01000020_gene4708	1.74e-09	66.6	COG1506@1|root,COG1506@2|Bacteria,2I2J3@201174|Actinobacteria	201174|Actinobacteria	E	peptidase	-	-	-	-	-	-	-	-	-	-	-	-	DUF1100,Peptidase_S9
k141_3295_2	1173263.Syn7502_00149	9.15e-27	100.0	COG0759@1|root,COG0759@2|Bacteria,1G90B@1117|Cyanobacteria,1H14U@1129|Synechococcus	1117|Cyanobacteria	S	Could be involved in insertion of integral membrane proteins into the membrane	-	-	-	ko:K08998	-	-	-	-	ko00000	-	-	-	Haemolytic
k141_3295_3	857087.Metme_4142	1.63e-24	97.1	COG0594@1|root,COG0594@2|Bacteria,1MZQE@1224|Proteobacteria,1S90M@1236|Gammaproteobacteria,1XFKR@135618|Methylococcales	135618|Methylococcales	J	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme	rnpA	-	3.1.26.5	ko:K03536	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Ribonuclease_P
k141_6400_1	338963.Pcar_1843	1.73e-58	203.0	COG3383@1|root,COG3383@2|Bacteria,1QTZB@1224|Proteobacteria,42SPZ@68525|delta/epsilon subdivisions,2WIV9@28221|Deltaproteobacteria,43VZE@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Molybdopterin oxidoreductase Fe4S4 domain	-	-	1.17.1.10,1.17.1.9	ko:K00123,ko:K05299	ko00630,ko00680,ko00720,ko01100,ko01120,ko01200,map00630,map00680,map00720,map01100,map01120,map01200	M00377	R00134,R00519	RC02796	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_4,Fer4,Fer4_7,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
k141_7009_1	445970.ALIPUT_00035	2.45e-57	192.0	COG0427@1|root,COG0427@2|Bacteria,4NFS3@976|Bacteroidetes,2FNCA@200643|Bacteroidia,22UB7@171550|Rikenellaceae	976|Bacteroidetes	C	Acetyl-CoA hydrolase transferase	-	-	-	-	-	-	-	-	-	-	-	-	AcetylCoA_hyd_C,AcetylCoA_hydro
k141_8822_1	1150469.RSPPHO_03262	0.000132	42.4	2D0VD@1|root,32T9B@2|Bacteria,1N8N8@1224|Proteobacteria,2UT48@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	COG NOG15344 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_3918_1	3075.A0A087S9Z0	2.7e-20	90.9	COG0356@1|root,KOG4665@2759|Eukaryota,37J5M@33090|Viridiplantae,34IHJ@3041|Chlorophyta	3041|Chlorophyta	C	ATP synthase A chain	-	-	-	ko:K02126	ko00190,ko01100,ko04714,ko05010,ko05012,ko05016,map00190,map01100,map04714,map05010,map05012,map05016	M00158	-	-	ko00000,ko00001,ko00002,ko03029	3.A.2.1	-	-	ATP-synt_A
k141_4547_1	292414.TM1040_2389	3e-101	319.0	COG0060@1|root,COG0060@2|Bacteria,1MVBQ@1224|Proteobacteria,2TR3N@28211|Alphaproteobacteria,4NBDK@97050|Ruegeria	28211|Alphaproteobacteria	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1,zf-FPG_IleRS
k141_2078_1	6500.XP_005102740.1	5.92e-107	342.0	COG2801@1|root,KOG0017@2759|Eukaryota,38F42@33154|Opisthokonta,3BA5H@33208|Metazoa,3CZSS@33213|Bilateria	33208|Metazoa	G	K02A2.6-like	-	-	-	-	-	-	-	-	-	-	-	-	RVT_1,rve,zf-H2C2
k141_1457_1	1123276.KB893257_gene2662	1.04e-51	176.0	COG0604@1|root,COG0604@2|Bacteria,4NEYW@976|Bacteroidetes,47J9J@768503|Cytophagia	976|Bacteroidetes	C	NAD(P)H quinone oxidoreductase, PIG3 family	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N_2
k141_5163_1	1163409.UUA_15853	4.35e-25	109.0	COG1835@1|root,COG1835@2|Bacteria,1MV2W@1224|Proteobacteria,1RQS2@1236|Gammaproteobacteria,1X634@135614|Xanthomonadales	135614|Xanthomonadales	I	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
k141_5771_1	426117.M446_1318	6e-93	289.0	COG0129@1|root,COG0129@2|Bacteria,1MV4I@1224|Proteobacteria,2TQRW@28211|Alphaproteobacteria,1JT9W@119045|Methylobacteriaceae	28211|Alphaproteobacteria	EG	Belongs to the IlvD Edd family	MA20_16960	-	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
k141_4548_1	1002340.AFCF01000013_gene2765	7.34e-99	293.0	COG1116@1|root,COG1116@2|Bacteria,1MUIM@1224|Proteobacteria,2TRHM@28211|Alphaproteobacteria,34E13@302485|Phaeobacter	28211|Alphaproteobacteria	P	ATPases associated with a variety of cellular activities	-	-	-	ko:K02049	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	ABC_tran
k141_3297_2	1515746.HR45_08235	6.05e-103	311.0	COG0312@1|root,COG0312@2|Bacteria,1MUSK@1224|Proteobacteria,1RMA5@1236|Gammaproteobacteria,2QA1Z@267890|Shewanellaceae	1236|Gammaproteobacteria	S	PFAM peptidase U62 modulator of DNA gyrase	tldD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564	-	ko:K03568	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
k141_9478_1	159749.E7BWH9	4.67e-118	349.0	COG3854@1|root,2QQ4X@2759|Eukaryota,2XEFS@2836|Bacillariophyta	2836|Bacillariophyta	L	AAA domain	ycf45	-	-	-	-	-	-	-	-	-	-	-	-
k141_3920_1	1280952.HJA_08172	3.4e-85	265.0	COG3004@1|root,COG3004@2|Bacteria,1MW15@1224|Proteobacteria,2TSI5@28211|Alphaproteobacteria,43XAX@69657|Hyphomonadaceae	28211|Alphaproteobacteria	P	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons	nhaA	-	-	ko:K03313	-	-	-	-	ko00000,ko02000	2.A.33.1	-	-	Na_H_antiport_1
k141_7011_1	1415778.JQMM01000001_gene1301	2.49e-131	388.0	COG0651@1|root,COG0651@2|Bacteria,1MV6V@1224|Proteobacteria,1RQK5@1236|Gammaproteobacteria,1J4SZ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	CP	Proton-conducting membrane transporter	-	-	-	ko:K05568	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	Proton_antipo_M
k141_4549_1	983544.Lacal_0202	6.55e-102	315.0	COG0317@1|root,COG0317@2|Bacteria,4NESY@976|Bacteroidetes,1HX98@117743|Flavobacteriia	976|Bacteroidetes	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	relA	-	2.7.6.5	ko:K00951	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
k141_1459_1	351348.Maqu_1920	8.68e-22	92.4	COG4103@1|root,COG4103@2|Bacteria,1N6YZ@1224|Proteobacteria,1SD1K@1236|Gammaproteobacteria,468DI@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	TerB
k141_7574_1	1116472.MGMO_41c00150	1.3e-56	179.0	COG1225@1|root,COG1225@2|Bacteria,1RD4R@1224|Proteobacteria,1RQ7F@1236|Gammaproteobacteria,1XF8T@135618|Methylococcales	135618|Methylococcales	O	Redoxin	-	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
k141_7574_2	396588.Tgr7_0824	7.12e-16	79.7	COG1875@1|root,COG1875@2|Bacteria,1MUX1@1224|Proteobacteria,1RMQN@1236|Gammaproteobacteria,1WWB1@135613|Chromatiales	135613|Chromatiales	T	SMART Nucleotide binding protein, PINc	-	-	-	ko:K07175	-	-	-	-	ko00000	-	-	-	PIN_4,PhoH
k141_8825_1	1283300.ATXB01000002_gene2889	4.38e-88	267.0	COG0656@1|root,COG0656@2|Bacteria,1MX6S@1224|Proteobacteria,1RQA1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Aldo keto	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
k141_6402_1	1411685.U062_00994	1.02e-26	112.0	COG0037@1|root,COG0037@2|Bacteria,1MU85@1224|Proteobacteria,1RN14@1236|Gammaproteobacteria,1J5PD@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	D	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	GO:0002097,GO:0002101,GO:0002136,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016879,GO:0032267,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	6.3.4.19	ko:K04075	-	-	R09597	RC02633,RC02634	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3,TilS,TilS_C
k141_3921_1	391593.RCCS2_09844	1.54e-114	343.0	COG0195@1|root,COG0195@2|Bacteria,1MWT7@1224|Proteobacteria,2TRQN@28211|Alphaproteobacteria,2P2FS@2433|Roseobacter	28211|Alphaproteobacteria	K	Participates in both transcription termination and antitermination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	HHH_5,KH_5,NusA_N,S1
k141_4550_1	525897.Dbac_0952	1.15e-66	217.0	COG0055@1|root,COG0055@2|Bacteria,1N6UZ@1224|Proteobacteria,42MWQ@68525|delta/epsilon subdivisions,2WM69@28221|Deltaproteobacteria,2MG2F@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	-	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
k141_849_1	977880.RALTA_B1630	2.02e-105	325.0	COG2838@1|root,COG2838@2|Bacteria,1MV6Q@1224|Proteobacteria,2VI36@28216|Betaproteobacteria,1K2J2@119060|Burkholderiaceae	28216|Betaproteobacteria	C	PFAM Isocitrate dehydrogenase NADP-dependent monomeric type	icd2	-	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	IDH
k141_9479_1	1370122.JHXQ01000002_gene2852	9.15e-53	180.0	COG3385@1|root,COG3385@2|Bacteria,1R8M9@1224|Proteobacteria,2UI32@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
k141_8209_2	7719.XP_002121256.2	9.02e-133	416.0	COG2801@1|root,KOG0017@2759|Eukaryota,38F42@33154|Opisthokonta,3BA5H@33208|Metazoa,3CWAK@33213|Bilateria,48B0V@7711|Chordata	33208|Metazoa	E	K02A2.6-like	-	-	-	-	-	-	-	-	-	-	-	-	RVT_1,SCAN,rve,zf-CCHC,zf-H2C2
k141_8209_3	10224.XP_006826129.1	1.38e-19	87.8	COG2801@1|root,KOG0017@2759|Eukaryota,38F42@33154|Opisthokonta,3BA5H@33208|Metazoa,3CWAK@33213|Bilateria	33208|Metazoa	E	K02A2.6-like	-	-	-	-	-	-	-	-	-	-	-	-	RVT_1,SCAN,rve,zf-CCHC,zf-H2C2
k141_7575_1	886377.Murru_2406	9.51e-88	280.0	COG0466@1|root,COG0466@2|Bacteria,4NE1G@976|Bacteroidetes,1HX2R@117743|Flavobacteriia	976|Bacteroidetes	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
k141_6403_1	1265507.KB899636_gene1810	9.09e-07	55.8	COG1757@1|root,COG1757@2|Bacteria,1MY5C@1224|Proteobacteria,1RP6I@1236|Gammaproteobacteria,1Y3WM@135624|Aeromonadales	135624|Aeromonadales	C	Na H antiporter	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_antiporter
k141_3922_1	1270196.JCKI01000001_gene3488	1.43e-41	145.0	COG1091@1|root,COG1091@2|Bacteria,4NE3K@976|Bacteroidetes,1IP3S@117747|Sphingobacteriia	976|Bacteroidetes	M	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose	rmlD	-	1.1.1.133	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777	RC00182	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
k141_3922_2	1484460.JSWG01000009_gene176	3.3e-13	68.2	COG1218@1|root,COG1218@2|Bacteria,4NFHY@976|Bacteroidetes,1HXAV@117743|Flavobacteriia	976|Bacteroidetes	P	COG1218 3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase	cysQ	-	3.1.3.7	ko:K01082	ko00920,ko01100,ko01120,ko01130,map00920,map01100,map01120,map01130	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03016	-	-	-	Inositol_P
k141_5168_1	1402135.SUH3_17665	1.23e-68	213.0	COG3916@1|root,COG3916@2|Bacteria,1MWPW@1224|Proteobacteria,2TVJ6@28211|Alphaproteobacteria,3ZUVY@60136|Sulfitobacter	28211|Alphaproteobacteria	QT	Autoinducer synthase	raiI	-	2.3.1.184	ko:K20249	ko00270,ko01100,ko02024,map00270,map01100,map02024	-	R08940	RC00021,RC00039	ko00000,ko00001,ko01000	-	-	-	Autoind_synth
k141_2700_1	159749.K0T004	8.88e-77	273.0	COG2801@1|root,KOG0017@2759|Eukaryota,2XEGG@2836|Bacillariophyta	2836|Bacillariophyta	L	transposition, RNA-mediated	-	-	-	-	-	-	-	-	-	-	-	-	RVT_2,gag_pre-integrs,rve,zf-CCHC
k141_7015_1	981336.F944_01817	2.29e-46	167.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,1MV6G@1224|Proteobacteria,1RMYD@1236|Gammaproteobacteria,3NJ8A@468|Moraxellaceae	1236|Gammaproteobacteria	E	B12 binding domain	metH	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006464,GO:0006479,GO:0006520,GO:0006555,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008213,GO:0008270,GO:0008276,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0019538,GO:0019752,GO:0019842,GO:0031419,GO:0032259,GO:0034641,GO:0035999,GO:0036094,GO:0036211,GO:0042084,GO:0042558,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046872,GO:0046906,GO:0046914,GO:0048037,GO:0050667,GO:0051186,GO:0071704,GO:0097159,GO:0140096,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	iECO103_1326.ECO103_4764,iECUMN_1333.ECUMN_4545	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
k141_3299_1	1049564.TevJSym_ak00800	2.3e-41	139.0	COG1544@1|root,COG1544@2|Bacteria,1MZHW@1224|Proteobacteria,1S8U1@1236|Gammaproteobacteria,1J6HN@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	COG1544 Ribosome-associated protein Y (PSrp-1)	yhbH	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006417,GO:0006448,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0017148,GO:0019222,GO:0022626,GO:0022627,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0043021,GO:0043022,GO:0043024,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0045900,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:1990904,GO:2000112,GO:2000113	-	ko:K05808	-	-	-	-	ko00000,ko03009	-	-	-	Ribosomal_S30AE
k141_3299_2	1049564.TevJSym_ak00810	2.71e-52	177.0	COG1508@1|root,COG1508@2|Bacteria,1MW4V@1224|Proteobacteria,1RMY0@1236|Gammaproteobacteria,1J4HB@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	rpoN	GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0032993,GO:0042802,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141	-	ko:K03092	ko02020,ko05111,map02020,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma54_AID,Sigma54_CBD,Sigma54_DBD
k141_226_1	1342299.Z947_3572	2.3e-110	322.0	COG3638@1|root,COG3638@2|Bacteria,1MVE9@1224|Proteobacteria,2TRR3@28211|Alphaproteobacteria,3ZW1F@60136|Sulfitobacter	28211|Alphaproteobacteria	P	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system	phnC	-	3.6.3.28	ko:K02041	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.9	-	-	ABC_tran
k141_8211_1	768671.ThimaDRAFT_3727	4.97e-29	107.0	2A022@1|root,30N4C@2|Bacteria,1PU9F@1224|Proteobacteria,1SCMU@1236|Gammaproteobacteria,1WYYW@135613|Chromatiales	135613|Chromatiales	S	Domain of unknown function (DUF1840)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1840
k141_8211_2	1408473.JHXO01000010_gene3671	2.36e-08	55.8	COG4677@1|root,COG4677@2|Bacteria,4NEEI@976|Bacteroidetes,2FMFM@200643|Bacteroidia	976|Bacteroidetes	G	Pectinesterase	-	-	3.1.1.11	ko:K01051	ko00040,ko01100,map00040,map01100	M00081	R02362	RC00460,RC00461	ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_3,Pec_lyase,Pectinesterase
k141_4001_2	1121428.DESHY_30084___1	7.29e-28	108.0	COG1014@1|root,COG1014@2|Bacteria,1V1DT@1239|Firmicutes,24HIC@186801|Clostridia,261U9@186807|Peptococcaceae	186801|Clostridia	C	PFAM pyruvate ferredoxin flavodoxin oxidoreductase	iorB	-	1.2.7.8	ko:K00180	-	-	-	-	br01601,ko00000,ko01000	-	-	-	POR
k141_8892_1	526222.Desal_3024	2.89e-108	330.0	COG0459@1|root,COG0459@2|Bacteria,1MURR@1224|Proteobacteria,42M52@68525|delta/epsilon subdivisions,2WIRK@28221|Deltaproteobacteria,2M84Y@213115|Desulfovibrionales	28221|Deltaproteobacteria	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
k141_8284_1	643562.Daes_1429	9.53e-72	219.0	COG2236@1|root,COG2236@2|Bacteria,1MWNE@1224|Proteobacteria,42RSU@68525|delta/epsilon subdivisions,2WMYZ@28221|Deltaproteobacteria,2MB60@213115|Desulfovibrionales	28221|Deltaproteobacteria	F	Acts on guanine, xanthine and to a lesser extent hypoxanthine	gpt	-	2.4.2.22	ko:K00769	ko00230,ko01100,ko01110,map00230,map01100,map01110	-	R01229,R02142	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
k141_2162_1	1229909.NSED_01190	5.31e-117	349.0	COG1053@1|root,arCOG00571@2157|Archaea,41SAM@651137|Thaumarchaeota	651137|Thaumarchaeota	C	fumarate reductase flavoprotein	-	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
k141_5239_1	1131553.JIBI01000020_gene218	7.24e-31	111.0	arCOG05874@1|root,2ZJ01@2|Bacteria,1N8VY@1224|Proteobacteria,2W4ZN@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_1539_1	585423.KR49_09000	1.57e-09	63.5	COG1459@1|root,COG1459@2|Bacteria,1G164@1117|Cyanobacteria,1GYBJ@1129|Synechococcus	1117|Cyanobacteria	U	Type II secretory pathway, component PulF	pilC	-	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
k141_7084_1	1415779.JOMH01000001_gene2803	7.8e-120	358.0	COG0034@1|root,COG0034@2|Bacteria,1MU0V@1224|Proteobacteria,1RMYA@1236|Gammaproteobacteria,1X3ZZ@135614|Xanthomonadales	135614|Xanthomonadales	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_6,Pribosyltran
k141_305_2	159749.E7BWE0	2.8e-122	353.0	COG0805@1|root,2QVCB@2759|Eukaryota	2759|Eukaryota	U	protein transport by the Tat complex	tatC	GO:0000003,GO:0003674,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006810,GO:0006886,GO:0006996,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009507,GO:0009534,GO:0009535,GO:0009536,GO:0009566,GO:0009567,GO:0009579,GO:0009657,GO:0009668,GO:0009977,GO:0009987,GO:0010027,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0019953,GO:0022414,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0031360,GO:0031361,GO:0031976,GO:0031984,GO:0032991,GO:0033036,GO:0033281,GO:0034357,GO:0034613,GO:0042651,GO:0042886,GO:0042887,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043235,GO:0043953,GO:0044422,GO:0044424,GO:0044425,GO:0044434,GO:0044435,GO:0044436,GO:0044444,GO:0044446,GO:0044459,GO:0044464,GO:0044703,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0051704,GO:0055035,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0098796,GO:0098797,GO:1904680	-	ko:K02634,ko:K03118	ko00195,ko01100,ko03060,ko03070,map00195,map01100,map03060,map03070	M00162,M00336	-	-	ko00000,ko00001,ko00002,ko00194,ko02044	2.A.64	-	-	TatC
k141_2163_1	1342299.Z947_1237	2.39e-113	332.0	COG1638@1|root,COG1638@2|Bacteria,1MVHI@1224|Proteobacteria,2TQVT@28211|Alphaproteobacteria,3ZVW5@60136|Sulfitobacter	28211|Alphaproteobacteria	G	Bacterial extracellular solute-binding protein, family 7	dctP_1	-	-	-	-	-	-	-	-	-	-	-	DctP
k141_1540_1	452637.Oter_4259	1.78e-105	313.0	COG0524@1|root,COG0524@2|Bacteria,46TGU@74201|Verrucomicrobia,3K7M0@414999|Opitutae	414999|Opitutae	G	pfkB family carbohydrate kinase	-	-	2.7.1.45	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00061,M00308,M00631	R01541	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PfkB
k141_306_1	309807.SRU_2221	2.04e-52	181.0	COG0165@1|root,COG0165@2|Bacteria,4NFCY@976|Bacteroidetes,1FJSI@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	E	Lyase	argH	GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Lyase_1
k141_5853_1	1122599.AUGR01000012_gene900	4.94e-81	248.0	arCOG03638@1|root,2Z8W3@2|Bacteria,1N2PH@1224|Proteobacteria,1RMI8@1236|Gammaproteobacteria,1XHVP@135619|Oceanospirillales	135619|Oceanospirillales	S	Protein of unknown function (DUF1538)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1538
k141_6479_1	1354722.JQLS01000005_gene3922	6.47e-114	351.0	COG1982@1|root,COG1982@2|Bacteria,1MWK4@1224|Proteobacteria,2TSSN@28211|Alphaproteobacteria,46NNT@74030|Roseovarius	28211|Alphaproteobacteria	E	Orn/Lys/Arg decarboxylase, C-terminal domain	-	-	4.1.1.19	ko:K01584	ko00330,ko01100,map00330,map01100	M00133	R00566	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	OKR_DC_1,OKR_DC_1_C
k141_8810_1	1415778.JQMM01000001_gene750	1.87e-05	49.7	COG1538@1|root,COG1538@2|Bacteria,1MWCJ@1224|Proteobacteria,1RQQV@1236|Gammaproteobacteria,1J52S@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	MU	COG1538 Outer membrane protein	tolC	-	-	ko:K12340	ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133	M00325,M00326,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko02044	1.B.17,2.A.6.2	-	-	OEP
k141_3910_1	1305735.JAFT01000005_gene2519	6.81e-59	193.0	COG0683@1|root,COG0683@2|Bacteria,1MUZU@1224|Proteobacteria,2TS7Z@28211|Alphaproteobacteria,2PF7C@252301|Oceanicola	28211|Alphaproteobacteria	E	Periplasmic binding protein domain	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_5
k141_836_1	159749.E7BWH1	1.45e-208	585.0	28JG1@1|root,2QRV6@2759|Eukaryota,2XEM0@2836|Bacillariophyta	2836|Bacillariophyta	P	One of the components of the core complex of photosystem II (PSII). It binds chlorophyll and helps catalyze the primary light-induced photochemical processes of PSII. PSII is a light- driven water plastoquinone oxidoreductase, using light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation	psbB	-	-	ko:K02704	ko00195,ko01100,map00195,map01100	M00161	-	-	ko00000,ko00001,ko00002,ko00194	-	-	-	PSII
k141_1445_1	267608.RSc2763	4.43e-35	131.0	COG1385@1|root,COG1385@2|Bacteria,1MXCU@1224|Proteobacteria,2VJS2@28216|Betaproteobacteria,1K1P3@119060|Burkholderiaceae	28216|Betaproteobacteria	J	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit	rsmE	-	2.1.1.193	ko:K09761	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_RNA
k141_2685_1	1089552.KI911559_gene2479	8.03e-51	169.0	COG1974@1|root,COG1974@2|Bacteria,1MW80@1224|Proteobacteria,2TT7W@28211|Alphaproteobacteria,2JQV9@204441|Rhodospirillales	204441|Rhodospirillales	K	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair	lexA	-	3.4.21.88	ko:K01356	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	LexA_DNA_bind,Peptidase_S24
k141_7001_1	391593.RCCS2_09854	1.46e-98	310.0	COG0532@1|root,COG0532@2|Bacteria,1MV26@1224|Proteobacteria,2TQMY@28211|Alphaproteobacteria,2P1J9@2433|Roseobacter	28211|Alphaproteobacteria	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,GTP_EFTU_D2,IF-2,IF2_N,IF2_assoc
k141_4538_1	158500.BV97_04400	1.22e-34	134.0	COG1109@1|root,COG1109@2|Bacteria,1MUB3@1224|Proteobacteria,2TUF4@28211|Alphaproteobacteria,2K8IG@204457|Sphingomonadales	204457|Sphingomonadales	G	Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I	-	-	5.4.2.8	ko:K01840	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01818	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
k141_7002_1	1234364.AMSF01000013_gene673	5.47e-62	209.0	COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,1RMQQ@1236|Gammaproteobacteria,1X45G@135614|Xanthomonadales	135614|Xanthomonadales	E	Acetolactate synthase	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
k141_8812_1	382464.ABSI01000013_gene1852	1.16e-66	213.0	COG2801@1|root,COG2801@2|Bacteria,46XGS@74201|Verrucomicrobia,2IVVH@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	HTH-like domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_21,rve
k141_6391_1	1117647.M5M_07135	1.04e-30	121.0	COG1033@1|root,COG1033@2|Bacteria,1MUE1@1224|Proteobacteria,1RNWM@1236|Gammaproteobacteria,1J4YY@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	exporters of the RND superfamily	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
k141_9467_1	35128.Thapsdraft1620	1.83e-148	422.0	COG2022@1|root,2RCR5@2759|Eukaryota,2XEJ1@2836|Bacillariophyta	2836|Bacillariophyta	H	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S	thiG	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009536,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464	-	-	-	-	-	-	-	-	-	-	ThiG
k141_7564_1	1173264.KI913949_gene267	5.66e-24	95.5	COG0784@1|root,COG0784@2|Bacteria,1GQ4W@1117|Cyanobacteria,1HI3B@1150|Oscillatoriales	1117|Cyanobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
k141_6392_1	543913.D521_0370	6.25e-114	348.0	COG2838@1|root,COG2838@2|Bacteria,1MV6Q@1224|Proteobacteria,2VI36@28216|Betaproteobacteria,1KQ7G@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	C	Monomeric isocitrate dehydrogenase	icd2	-	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	IDH
k141_3292_1	639030.JHVA01000001_gene1491	3.44e-08	53.9	COG3247@1|root,COG3247@2|Bacteria,3Y5AN@57723|Acidobacteria,2JJYZ@204432|Acidobacteriia	204432|Acidobacteriia	S	Short repeat of unknown function (DUF308)	-	-	-	-	-	-	-	-	-	-	-	-	DUF308
k141_3292_2	935567.JAES01000004_gene33	0.000124	46.6	COG1502@1|root,COG1502@2|Bacteria,1MUDJ@1224|Proteobacteria,1RMIF@1236|Gammaproteobacteria,1X4QW@135614|Xanthomonadales	135614|Xanthomonadales	I	Cardiolipin synthase	-	-	-	ko:K06132	ko00564,ko01100,map00564,map01100	-	R11062	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2
k141_3914_1	744979.R2A130_3259	4.87e-53	185.0	COG4670@1|root,COG4670@2|Bacteria,1MUJW@1224|Proteobacteria,2TRRK@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	CoA transferase having broad substrate specificity for short-chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons	pct	-	2.8.3.1	ko:K01026	ko00620,ko00640,ko00643,ko01100,ko01120,map00620,map00640,map00643,map01100,map01120	-	R00928,R01449,R05508	RC00012,RC00014,RC00137	ko00000,ko00001,ko01000	-	-	-	CoA_trans
k141_5157_1	159749.E7BWE1	2.72e-64	205.0	2CMAK@1|root,2QPT8@2759|Eukaryota,2XE9B@2836|Bacillariophyta	2836|Bacillariophyta	C	Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions	petA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009536,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464	-	ko:K02634	ko00195,ko01100,map00195,map01100	M00162	-	-	ko00000,ko00001,ko00002,ko00194	-	-	-	Apocytochr_F_C,Apocytochr_F_N
k141_4541_1	56780.SYN_02668	1.82e-15	82.0	COG0451@1|root,COG0451@2|Bacteria,1MX2J@1224|Proteobacteria,42PPG@68525|delta/epsilon subdivisions,2WJGF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM NAD-dependent epimerase dehydratase	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
k141_1450_1	388739.RSK20926_14781	2.86e-14	69.7	COG0394@1|root,COG0394@2|Bacteria,1RH90@1224|Proteobacteria,2U72X@28211|Alphaproteobacteria,2P3HF@2433|Roseobacter	28211|Alphaproteobacteria	T	Belongs to the low molecular weight phosphotyrosine protein phosphatase family	ptpA	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
k141_1450_2	391593.RCCS2_03924	5.21e-50	160.0	2E38C@1|root,32Y82@2|Bacteria,1N7QR@1224|Proteobacteria,2UFKA@28211|Alphaproteobacteria,2P3S1@2433|Roseobacter	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_840_2	1255043.TVNIR_2694	9.25e-43	152.0	COG0859@1|root,COG0859@2|Bacteria,1MYZA@1224|Proteobacteria,1RR6K@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	heptosyltransferase	opsX	-	-	ko:K12982	-	-	-	-	ko00000,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
k141_7567_1	420324.KI912086_gene7387	1.38e-58	193.0	COG3547@1|root,COG3547@2|Bacteria,1MUER@1224|Proteobacteria,2TSGZ@28211|Alphaproteobacteria,1JUJU@119045|Methylobacteriaceae	28211|Alphaproteobacteria	L	PFAM transposase IS116 IS110 IS902 family	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k141_8203_1	435838.HMPREF0786_01670	0.000241	41.2	COG0230@1|root,COG0230@2|Bacteria,1VK90@1239|Firmicutes,4HR2Z@91061|Bacilli,4GZW8@90964|Staphylococcaceae	91061|Bacilli	J	Belongs to the bacterial ribosomal protein bL34 family	rpmH	-	-	ko:K02914	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L34
k141_8203_2	1265507.KB899636_gene1819	1.51e-10	64.7	COG0653@1|root,COG0653@2|Bacteria,1MUJZ@1224|Proteobacteria,1RM9M@1236|Gammaproteobacteria,1Y460@135624|Aeromonadales	135624|Aeromonadales	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	-	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
k141_4542_1	626887.J057_21335	7.91e-51	176.0	COG0174@1|root,COG0174@2|Bacteria,1MU6V@1224|Proteobacteria,1RPNZ@1236|Gammaproteobacteria,465I0@72275|Alteromonadaceae	1236|Gammaproteobacteria	E	Glutamine synthetase, catalytic domain	-	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C
k141_2073_1	1260251.SPISAL_00040	3.72e-136	391.0	COG0752@1|root,COG0752@2|Bacteria,1MVCJ@1224|Proteobacteria,1RMYI@1236|Gammaproteobacteria,1WWUE@135613|Chromatiales	135613|Chromatiales	J	glycyl-tRNA synthetase alpha subunit	glyQ	-	6.1.1.14	ko:K01878	ko00970,map00970	M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2e
k141_6394_1	439496.RBY4I_730	4.73e-172	482.0	COG2801@1|root,COG2801@2|Bacteria,1MVN5@1224|Proteobacteria,2TQK0@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	COG2801 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	HTH_21,rve,rve_3
k141_217_1	580332.Slit_1714	1.37e-73	222.0	COG1146@1|root,COG1146@2|Bacteria,1R4GP@1224|Proteobacteria,2W0BB@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Adenosine-5'-phosphosulfate reductase beta subunit	-	-	1.8.99.2	ko:K00395	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00596	R00860,R04927,R08553	RC00007,RC01239,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	-	APS-reductase_C,Fer4
k141_217_2	580332.Slit_1713	1.38e-111	328.0	2BX2I@1|root,2Z9KR@2|Bacteria,1MXKC@1224|Proteobacteria,2W0AA@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_5766_1	998674.ATTE01000001_gene1411	1.16e-152	442.0	COG0312@1|root,COG0312@2|Bacteria,1MUSK@1224|Proteobacteria,1RMA5@1236|Gammaproteobacteria,4607U@72273|Thiotrichales	1236|Gammaproteobacteria	S	modulator of DNA gyrase	-	-	-	-	-	-	-	-	-	-	-	-	PmbA_TldD
k141_3916_1	388401.RB2150_04953	5.83e-51	165.0	COG0848@1|root,COG0848@2|Bacteria,1MZ6M@1224|Proteobacteria,2UA46@28211|Alphaproteobacteria,3ZHBI@58840|unclassified Rhodobacteraceae	28211|Alphaproteobacteria	U	Biopolymer transport protein	tolR	-	-	ko:K03559,ko:K03560	-	-	-	-	ko00000,ko02000	1.A.30.2.1,1.A.30.2.2	-	-	ExbD
k141_3916_2	391613.RTM1035_18951	4.42e-16	76.6	COG3266@1|root,COG3266@2|Bacteria,1PZDQ@1224|Proteobacteria,2U2MW@28211|Alphaproteobacteria,46Q9N@74030|Roseovarius	28211|Alphaproteobacteria	S	Cell division and transport-associated protein TolA	tolA	-	-	ko:K03646	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	-
k141_6395_1	1121875.KB907547_gene3238	8.1e-85	274.0	COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,4NDX3@976|Bacteroidetes,1HY9Q@117743|Flavobacteriia	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k141_9471_1	382245.ASA_4331	6.99e-32	118.0	COG3415@1|root,COG3415@2|Bacteria,1RFNA@1224|Proteobacteria,1S5WD@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	COG2963 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	HTH_23,HTH_Tnp_1
k141_2692_1	270374.MELB17_19079	1.07e-91	280.0	COG0205@1|root,COG0205@2|Bacteria,1MVN3@1224|Proteobacteria,1RMVY@1236|Gammaproteobacteria,465WX@72275|Alteromonadaceae	1236|Gammaproteobacteria	G	Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions	pfp	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
k141_5251_1	1121007.AUML01000034_gene1778	9.84e-105	305.0	COG0450@1|root,COG0450@2|Bacteria,4NEZZ@976|Bacteroidetes,1I036@117743|Flavobacteriia,2YHW2@290174|Aquimarina	976|Bacteroidetes	O	C-terminal domain of 1-Cys peroxiredoxin	-	-	1.11.1.15	ko:K03386	ko04214,map04214	-	-	-	ko00000,ko00001,ko01000,ko04147	-	-	-	1-cysPrx_C,AhpC-TSA
k141_1551_1	697282.Mettu_2397	1.51e-93	290.0	COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,1RMQQ@1236|Gammaproteobacteria,1XENG@135618|Methylococcales	135618|Methylococcales	H	Thiamine pyrophosphate enzyme, N-terminal TPP binding	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
k141_5252_1	1027273.GZ77_08790	4.99e-68	216.0	COG0761@1|root,COG0761@2|Bacteria,1MU7G@1224|Proteobacteria,1RMN8@1236|Gammaproteobacteria,1XH7J@135619|Oceanospirillales	135619|Oceanospirillales	IM	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis	ispH	-	1.17.7.4	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05884,R08210	RC01137,RC01487	ko00000,ko00001,ko00002,ko01000	-	-	-	LYTB
k141_5864_1	247634.GPB2148_2189	2.94e-13	75.5	COG0501@1|root,COG0501@2|Bacteria,1MVU4@1224|Proteobacteria,1RPJ5@1236|Gammaproteobacteria,1J4XE@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	O	COG0501 Zn-dependent protease with chaperone function	htpX	-	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	Peptidase_M48
k141_932_1	1267535.KB906767_gene2749	4.91e-29	112.0	COG3620@1|root,COG3620@2|Bacteria,3Y6X6@57723|Acidobacteria	57723|Acidobacteria	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
k141_2782_1	159749.K0SZZ0	9.06e-07	53.9	COG2801@1|root,KOG0017@2759|Eukaryota,2XHT0@2836|Bacillariophyta	159749.K0SZZ0|-	O	transposition, RNA-mediated	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_1553_1	1366050.N234_31280	1.67e-134	392.0	COG3396@1|root,COG3396@2|Bacteria,1MXUK@1224|Proteobacteria,2VH89@28216|Betaproteobacteria,1K485@119060|Burkholderiaceae	28216|Betaproteobacteria	S	benzoyl-CoA oxygenase	boxB	-	1.14.13.208	ko:K15512	ko00362,map00362	-	R09555	RC01739	ko00000,ko00001,ko01000	-	-	-	-
k141_7663_1	631454.N177_0638	3.57e-52	181.0	COG0043@1|root,COG0043@2|Bacteria,1MU62@1224|Proteobacteria,2TTSQ@28211|Alphaproteobacteria,1JP5H@119043|Rhodobiaceae	28211|Alphaproteobacteria	H	3-octaprenyl-4-hydroxybenzoate carboxy-lyase	-	-	4.1.1.98	ko:K03182	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04985,R04986	RC00391	ko00000,ko00001,ko00002,ko01000	-	-	-	UbiD
k141_5254_1	1131553.JIBI01000012_gene817	1.27e-24	102.0	COG0111@1|root,COG0111@2|Bacteria,1MU5Z@1224|Proteobacteria,2VIHG@28216|Betaproteobacteria,371V7@32003|Nitrosomonadales	28216|Betaproteobacteria	C	D-isomer specific 2-hydroxyacid dehydrogenase	serA	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
k141_5254_2	1385517.N800_04700	4.19e-50	171.0	COG0077@1|root,COG1605@1|root,COG0077@2|Bacteria,COG1605@2|Bacteria,1MU60@1224|Proteobacteria,1RNRD@1236|Gammaproteobacteria,1X4R7@135614|Xanthomonadales	135614|Xanthomonadales	E	Prephenate dehydratase	pheA	-	4.2.1.51,5.4.99.5	ko:K14170	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R00691,R01373,R01715	RC00360,RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,CM_2,PDT
k141_5866_1	443144.GM21_3094	3.29e-30	112.0	COG2818@1|root,COG2818@2|Bacteria,1R9X5@1224|Proteobacteria,42QWV@68525|delta/epsilon subdivisions,2WMPT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	PFAM Methyladenine glycosylase	tag	-	3.2.2.20	ko:K01246	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Adenine_glyco
k141_5866_2	1038869.AXAN01000009_gene4687	1.48e-25	105.0	COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,2WEKR@28216|Betaproteobacteria,1KHRR@119060|Burkholderiaceae	28216|Betaproteobacteria	E	aminotransferase class I and II	-	-	2.6.1.84	ko:K12252	ko00330,ko01100,map00330,map01100	-	R08197	RC00006,RC00008	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
k141_320_1	1229909.NSED_00590	5.93e-43	148.0	COG1270@1|root,arCOG04274@2157|Archaea,41S6I@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group	cobD	-	6.3.1.10	ko:K02227	ko00860,ko01100,map00860,map01100	M00122	R06529,R07302	RC00090,RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	CobD_Cbib
k141_320_2	1229909.NSED_00595	2.23e-85	258.0	COG0368@1|root,arCOG04338@2157|Archaea,41SI6@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate	cobS	-	2.7.8.26	ko:K02233	ko00860,ko01100,map00860,map01100	M00122	R05223,R11174	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CobS
k141_4642_1	1229909.NSED_01325	2.3e-176	509.0	COG1009@1|root,arCOG01539@2157|Archaea,41SC4@651137|Thaumarchaeota	651137|Thaumarchaeota	C	TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain L	-	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M,Proton_antipo_N
k141_7099_1	870187.Thini_4072	5e-88	284.0	COG0178@1|root,COG0178@2|Bacteria,1MW0W@1224|Proteobacteria,1RMS9@1236|Gammaproteobacteria,4606D@72273|Thiotrichales	72273|Thiotrichales	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
k141_934_1	61273.S3BUW2	3.86e-08	58.5	COG0642@1|root,KOG0519@2759|Eukaryota,391YN@33154|Opisthokonta,3NV7C@4751|Fungi,3QPHU@4890|Ascomycota,216I3@147550|Sordariomycetes,3USWP@5151|Ophiostomatales	4751|Fungi	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	CHK1	GO:0000155,GO:0000160,GO:0001932,GO:0001934,GO:0002831,GO:0002833,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0007154,GO:0007162,GO:0007165,GO:0008150,GO:0008152,GO:0009272,GO:0009365,GO:0009405,GO:0009607,GO:0009893,GO:0009966,GO:0009967,GO:0009987,GO:0010033,GO:0010562,GO:0010570,GO:0010604,GO:0010646,GO:0010647,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0018106,GO:0018193,GO:0018202,GO:0019220,GO:0019222,GO:0019538,GO:0022407,GO:0022408,GO:0023014,GO:0023051,GO:0023052,GO:0023056,GO:0030100,GO:0030155,GO:0030447,GO:0031323,GO:0031325,GO:0031399,GO:0031401,GO:0032268,GO:0032270,GO:0032872,GO:0032874,GO:0032879,GO:0032991,GO:0033554,GO:0033993,GO:0034599,GO:0035556,GO:0036180,GO:0036211,GO:0040007,GO:0040008,GO:0042221,GO:0042325,GO:0042327,GO:0042546,GO:0042710,GO:0043170,GO:0043408,GO:0043410,GO:0043412,GO:0043900,GO:0044010,GO:0044011,GO:0044085,GO:0044182,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044419,GO:0044424,GO:0044464,GO:0044764,GO:0045806,GO:0045927,GO:0045937,GO:0046677,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048584,GO:0050764,GO:0050765,GO:0050789,GO:0050794,GO:0050896,GO:0051040,GO:0051042,GO:0051049,GO:0051051,GO:0051128,GO:0051129,GO:0051171,GO:0051173,GO:0051174,GO:0051246,GO:0051247,GO:0051703,GO:0051704,GO:0051716,GO:0060255,GO:0060627,GO:0061695,GO:0065007,GO:0070302,GO:0070304,GO:0070887,GO:0070994,GO:0071236,GO:0071310,GO:0071396,GO:0071554,GO:0071704,GO:0071840,GO:0071852,GO:0080090,GO:0080134,GO:0080135,GO:0090033,GO:0090605,GO:0090609,GO:0097305,GO:0097306,GO:0097307,GO:0097308,GO:0140096,GO:1900190,GO:1900231,GO:1900428,GO:1900430,GO:1900443,GO:1900445,GO:1901564,GO:1901700,GO:1901701,GO:1902494,GO:1902531,GO:1902533,GO:1902911,GO:1990234	2.7.13.3	ko:K19690	ko02020,map02020	M00516	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	AAA_16,GAF,GAF_2,HATPase_c,HisKA,Pkinase,Response_reg
k141_2174_1	391589.RGAI101_995	4.54e-103	310.0	COG3666@1|root,COG3666@2|Bacteria,1QW5T@1224|Proteobacteria,2TWNW@28211|Alphaproteobacteria,2P5BX@2433|Roseobacter	28211|Alphaproteobacteria	L	L COG3039 Transposase and inactivated derivatives, IS5 family	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_6,DUF772
k141_6494_1	1265503.KB905181_gene3779	2.2e-30	124.0	COG1061@1|root,COG1061@2|Bacteria,1MV9F@1224|Proteobacteria,1RNAN@1236|Gammaproteobacteria,2Q7H4@267889|Colwelliaceae	1236|Gammaproteobacteria	L	helicase superfamily c-terminal domain	yejH	GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009314,GO:0009628,GO:0009987,GO:0010212,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0033554,GO:0034641,GO:0042221,GO:0042493,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051301,GO:0051716,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360	-	ko:K19789	-	-	-	-	ko00000,ko03400	-	-	-	Helicase_C,ResIII
k141_4643_1	35128.Thapsdraft1267	2.64e-144	444.0	COG0085@1|root,KOG0214@2759|Eukaryota,2XEM3@2836|Bacillariophyta	2836|Bacillariophyta	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	-	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009536,GO:0030880,GO:0032991,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0061695,GO:1902494,GO:1990234	-	-	-	-	-	-	-	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
k141_3369_1	105559.Nwat_2727	5.51e-17	83.6	COG0784@1|root,COG2199@1|root,COG2200@1|root,COG0784@2|Bacteria,COG2199@2|Bacteria,COG2200@2|Bacteria,1PJCA@1224|Proteobacteria,1RS4H@1236|Gammaproteobacteria,1WWNV@135613|Chromatiales	135613|Chromatiales	T	PFAM EAL domain	-	-	-	ko:K21025	ko02025,map02025	-	-	-	ko00000,ko00001	-	-	-	EAL,GGDEF,PAS,PAS_8,PAS_9,Response_reg
k141_4001_1	1187851.A33M_0066	9.66e-29	114.0	COG4231@1|root,COG4231@2|Bacteria,1MUKS@1224|Proteobacteria,2TSHH@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	COG4231 Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits	iorA	-	1.2.7.8	ko:K00179	-	-	-	-	br01601,ko00000,ko01000	-	-	-	Fer4_10,POR_N,TPP_enzyme_C
k141_5955_1	522306.CAP2UW1_1586	1.45e-82	260.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,2VH80@28216|Betaproteobacteria,1KQMW@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
k141_3465_1	754476.Q7A_993	3.54e-43	153.0	COG0787@1|root,COG0787@2|Bacteria,1MV0Q@1224|Proteobacteria,1RM8U@1236|Gammaproteobacteria,45ZWW@72273|Thiotrichales	72273|Thiotrichales	E	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	alr	-	5.1.1.1	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N
k141_3465_2	416269.APL_0713	1.79e-09	58.2	COG0305@1|root,COG0305@2|Bacteria,1MUG9@1224|Proteobacteria,1RPM2@1236|Gammaproteobacteria,1Y7T2@135625|Pasteurellales	135625|Pasteurellales	L	it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins	dnaB	GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0032392,GO:0032508,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
k141_1024_1	743299.Acife_2121	4.69e-11	65.9	COG1741@1|root,COG1741@2|Bacteria,1MVSW@1224|Proteobacteria,1RNVS@1236|Gammaproteobacteria,2NE58@225057|Acidithiobacillales	225057|Acidithiobacillales	S	Pirin	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin
k141_4114_1	351016.RAZWK3B_11306	2.91e-42	141.0	2DNPH@1|root,32YF1@2|Bacteria,1NARM@1224|Proteobacteria,2UJNP@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_7191_1	396588.Tgr7_0991	1.17e-121	357.0	COG1894@1|root,COG1894@2|Bacteria,1MV8F@1224|Proteobacteria,1RMUD@1236|Gammaproteobacteria,1WWH3@135613|Chromatiales	135613|Chromatiales	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain	nuoF	-	1.6.5.3	ko:K00335	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_51K,NADH_4Fe-4S,SLBB
k141_6577_1	187272.Mlg_1338	2.12e-134	397.0	COG0029@1|root,COG0029@2|Bacteria,1RBQW@1224|Proteobacteria,1RMMD@1236|Gammaproteobacteria,1WWEZ@135613|Chromatiales	135613|Chromatiales	H	Catalyzes the oxidation of L-aspartate to iminoaspartate	-	-	1.4.3.16	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	M00115	R00357,R00481	RC00006,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
k141_5352_1	331869.BAL199_23799	1.63e-09	58.5	COG0044@1|root,COG0044@2|Bacteria,1MVXY@1224|Proteobacteria,2TSTM@28211|Alphaproteobacteria,4BPRA@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	F	Amidohydrolase family	pyrC	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
k141_5352_2	990285.RGCCGE502_07671	7.43e-07	52.8	COG0010@1|root,COG0010@2|Bacteria,1MVFH@1224|Proteobacteria,2TR41@28211|Alphaproteobacteria,4B9S6@82115|Rhizobiaceae	28211|Alphaproteobacteria	E	Belongs to the arginase family	speB	-	3.5.3.11	ko:K01480	ko00330,ko01100,map00330,map01100	M00133	R01157	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
k141_5352_3	66874.JOFS01000008_gene2539	2.33e-07	53.1	COG0381@1|root,COG0381@2|Bacteria,2GJWS@201174|Actinobacteria	201174|Actinobacteria	M	Belongs to the UDP-N-acetylglucosamine 2-epimerase family	rffE	-	5.1.3.14	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	M00362	R00420	RC00290	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase_2
k141_5956_1	1417296.U879_08100	5.01e-05	44.3	2AKRU@1|root,31BIQ@2|Bacteria,1Q7DM@1224|Proteobacteria,2UEKS@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_5956_2	608538.HTH_1874	2.05e-44	149.0	COG0509@1|root,COG0509@2|Bacteria	2|Bacteria	E	glycine decarboxylation via glycine cleavage system	gcvH	-	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	-	GCV_H
k141_5956_3	1123366.TH3_13184	8.9e-11	59.7	COG0640@1|root,COG0640@2|Bacteria,1N72Q@1224|Proteobacteria,2UFSY@28211|Alphaproteobacteria,2JT9E@204441|Rhodospirillales	204441|Rhodospirillales	K	transcriptional regulators	-	-	-	ko:K22042	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5
k141_9642_1	314264.ROS217_15305	6.59e-79	245.0	COG2931@1|root,COG2931@2|Bacteria,1R6NH@1224|Proteobacteria,2U10I@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	Hint domain	-	-	-	-	-	-	-	-	-	-	-	-	Hint_2
k141_5353_1	1415778.JQMM01000001_gene1070	4.58e-88	267.0	COG1703@1|root,COG1703@2|Bacteria,1MVI0@1224|Proteobacteria,1RP15@1236|Gammaproteobacteria,1J4Q4@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	E	periplasmic protein kinase ArgK and related GTPases of G3E family	argK	GO:0003674,GO:0003824,GO:0003924,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111	-	ko:K07588	-	-	-	-	ko00000,ko01000	-	-	-	ArgK
k141_7761_1	93220.LV28_23595	6.56e-17	83.2	COG1235@1|root,COG1235@2|Bacteria,1R5N4@1224|Proteobacteria,2VKSE@28216|Betaproteobacteria,1K1VX@119060|Burkholderiaceae	28216|Betaproteobacteria	S	beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
k141_1651_1	926561.KB900618_gene244	6.38e-20	93.6	COG5002@1|root,COG5002@2|Bacteria,1TPSK@1239|Firmicutes,24A2N@186801|Clostridia,3WBHI@53433|Halanaerobiales	186801|Clostridia	T	histidine kinase HAMP region domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
k141_7194_1	1131814.JAFO01000001_gene2538	3.68e-76	238.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,2TREJ@28211|Alphaproteobacteria,3F0S9@335928|Xanthobacteraceae	28211|Alphaproteobacteria	C	Acyl-CoA dehydrogenase, middle domain	ivd2	-	1.3.8.4	ko:K00253	ko00280,ko01100,map00280,map01100	M00036	R04095	RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
k141_7194_2	1121479.AUBS01000003_gene4215	6.03e-05	45.1	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,2TQQ7@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	Belongs to the thiolase family	thlA	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
k141_4117_1	1123377.AUIV01000029_gene639	3.72e-37	134.0	COG1678@1|root,COG1678@2|Bacteria,1RCXM@1224|Proteobacteria,1S3YV@1236|Gammaproteobacteria,1X41Z@135614|Xanthomonadales	135614|Xanthomonadales	K	Belongs to the UPF0301 (AlgH) family	algH	-	-	ko:K07735	-	-	-	-	ko00000,ko03000	-	-	-	DUF179
k141_1652_1	795666.MW7_2906	2.62e-22	100.0	COG0243@1|root,COG0243@2|Bacteria,1NR6J@1224|Proteobacteria,2VJQ4@28216|Betaproteobacteria,1K5E8@119060|Burkholderiaceae	28216|Betaproteobacteria	C	Molydopterin dinucleotide binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_6,Fer2,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NAD_binding_1
k141_8988_2	45157.CMV228CT	2.62e-13	63.2	2C8JW@1|root,2SBI8@2759|Eukaryota	2759|Eukaryota	S	photosynthesis	psbJ	-	-	ko:K02711	ko00195,ko01100,map00195,map01100	-	-	-	ko00000,ko00001,ko00194	-	-	-	PsbJ
k141_4118_1	1249627.D779_1574	6.01e-61	195.0	COG2197@1|root,COG2197@2|Bacteria,1NQH7@1224|Proteobacteria,1RNXI@1236|Gammaproteobacteria,1WWCR@135613|Chromatiales	135613|Chromatiales	K	response regulator receiver	-	-	-	ko:K07684	ko02020,map02020	M00471	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
k141_2885_1	436308.Nmar_0061	1.18e-139	396.0	COG5491@1|root,arCOG00452@2157|Archaea,41SJ3@651137|Thaumarchaeota	651137|Thaumarchaeota	D	conserved protein implicated in secretion	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_1028_1	1239415.CM001837_gene1776	1.17e-111	333.0	COG0654@1|root,COG0654@2|Bacteria,4NGIU@976|Bacteroidetes,1HXAE@117743|Flavobacteriia,37E51@326319|Dokdonia	976|Bacteroidetes	CH	FAD binding domain	kmo	-	1.14.13.9	ko:K00486	ko00380,ko01100,map00380,map01100	M00038	R01960	RC00046	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_3
k141_1653_2	159749.E7BWN5	4.71e-39	141.0	COG0201@1|root,2QSNV@2759|Eukaryota	2759|Eukaryota	U	protein transport	secY	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006996,GO:0008150,GO:0009507,GO:0009534,GO:0009535,GO:0009536,GO:0009579,GO:0009657,GO:0009668,GO:0009987,GO:0010027,GO:0016020,GO:0016043,GO:0031976,GO:0031984,GO:0034357,GO:0042651,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044436,GO:0044444,GO:0044446,GO:0044464,GO:0055035,GO:0061024,GO:0071840	-	ko:K10956	ko03060,ko04141,ko04145,ko05110,map03060,map04141,map04145,map05110	M00401	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.4,3.A.5.8,3.A.5.9	-	-	SecY
k141_9646_1	1232683.ADIMK_0725	1.77e-32	123.0	COG4663@1|root,COG4663@2|Bacteria,1MVMD@1224|Proteobacteria,1RY6Q@1236|Gammaproteobacteria,469XK@72275|Alteromonadaceae	1236|Gammaproteobacteria	Q	Bacterial extracellular solute-binding protein, family 7	-	-	-	-	-	-	-	-	-	-	-	-	DctP
k141_5961_2	1131269.AQVV01000014_gene182	1.51e-26	103.0	COG2518@1|root,COG2518@2|Bacteria	2|Bacteria	O	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	pcm	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
k141_7765_1	107636.JQNK01000009_gene3513	5.95e-87	271.0	COG3666@1|root,COG3666@2|Bacteria,1N3QR@1224|Proteobacteria,2TRXG@28211|Alphaproteobacteria,370BU@31993|Methylocystaceae	28211|Alphaproteobacteria	L	Transposase DDE domain	-	-	-	ko:K07487	-	-	-	-	ko00000	-	-	-	DDE_Tnp_1,DDE_Tnp_1_6,DUF772
k141_2272_1	859653.HIMB5_00010610	1.87e-27	112.0	COG0823@1|root,COG0823@2|Bacteria,1MV09@1224|Proteobacteria,2TR03@28211|Alphaproteobacteria,4BPJM@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	U	Involved in the TonB-independent uptake of proteins	tolB	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40,TolB_N
k141_1654_1	227377.CBU_0521	2.94e-44	158.0	COG0402@1|root,COG0402@2|Bacteria,1MVPA@1224|Proteobacteria,1RN13@1236|Gammaproteobacteria,1JGMF@118969|Legionellales	118969|Legionellales	F	Amidohydrolase family	-	-	3.5.4.28,3.5.4.3,3.5.4.31	ko:K01487,ko:K12960	ko00230,ko00270,ko01100,map00230,map00270,map01100	-	R01676,R09660	RC00204,RC00477	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
k141_1654_2	34506.g5968	8.46e-14	70.5	COG0209@1|root,COG2227@1|root,KOG1112@2759|Eukaryota,KOG1270@2759|Eukaryota,38B81@33154|Opisthokonta,3B9IQ@33208|Metazoa,3CUAM@33213|Bilateria,40AHX@6231|Nematoda,1KU4Z@119089|Chromadorea,40WXW@6236|Rhabditida	33208|Metazoa	F	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides	-	-	-	-	-	-	-	-	-	-	-	-	ATP-cone,Ribonuc_red_lgC,Ribonuc_red_lgN
k141_6584_1	237368.SCABRO_00745	7.39e-46	160.0	COG0477@1|root,COG2814@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	ycaD	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
k141_8399_1	279238.Saro_3172	5.98e-22	96.3	COG0667@1|root,COG0667@2|Bacteria,1MVEH@1224|Proteobacteria,2TRHS@28211|Alphaproteobacteria,2K0VS@204457|Sphingomonadales	204457|Sphingomonadales	C	aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
k141_7766_1	519989.ECTPHS_02516	5.62e-61	206.0	COG0768@1|root,COG0768@2|Bacteria,1MV8C@1224|Proteobacteria,1RN9H@1236|Gammaproteobacteria,1WWAT@135613|Chromatiales	135613|Chromatiales	M	Catalyzes cross-linking of the peptidoglycan cell wall	mrdA	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	PBP_dimer,Transpeptidase
k141_9648_1	1443111.JASG01000004_gene3109	3.89e-89	266.0	293ZC@1|root,2ZREC@2|Bacteria,1RDYU@1224|Proteobacteria,2U7U4@28211|Alphaproteobacteria,3ZYEV@60136|Sulfitobacter	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_8991_1	746697.Aeqsu_3149	0.000842	47.0	COG0457@1|root,COG1680@1|root,COG0457@2|Bacteria,COG1680@2|Bacteria,4NI1Z@976|Bacteroidetes,1HYQF@117743|Flavobacteriia	976|Bacteroidetes	V	COG1680 Beta-lactamase class C and other penicillin binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,DUF3471,SusF_SusE
k141_4122_1	157072.XP_008866696.1	7.09e-27	110.0	2CMKC@1|root,2QQNW@2759|Eukaryota	2759|Eukaryota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_3469_1	666509.RCA23_c01120	1.4e-16	82.8	COG0626@1|root,COG0626@2|Bacteria,1MU57@1224|Proteobacteria,2TW14@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	COG0626 Cystathionine beta-lyases cystathionine gamma-synthases	metB	-	2.5.1.48	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017	R00999,R01288,R02508,R03217,R03260,R04944,R04945,R04946	RC00020,RC00056,RC00069,RC00420,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000	-	-	-	Cys_Met_Meta_PP
k141_7198_1	220664.PFL_0797	7.52e-16	75.9	28MU9@1|root,2ZB26@2|Bacteria,1N48H@1224|Proteobacteria,1SRIU@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF3726)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3726
k141_7198_2	1288298.rosmuc_03133	8.18e-71	231.0	COG4367@1|root,COG4367@2|Bacteria,1MU6T@1224|Proteobacteria,2TR0D@28211|Alphaproteobacteria,46P5E@74030|Roseovarius	28211|Alphaproteobacteria	K	negative regulation of transcription, DNA-templated	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_7767_1	666509.RCA23_c18290	1.07e-90	290.0	COG1048@1|root,COG1048@2|Bacteria,1MU9T@1224|Proteobacteria,2TT3T@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate	acnA	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0003994,GO:0005488,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019541,GO:0019679,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0045333,GO:0046459,GO:0047456,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0072350,GO:0097159,GO:1901363	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
k141_1031_2	35128.Thapsdraft1327	2.1e-69	226.0	COG0305@1|root,2QRXQ@2759|Eukaryota,2XEMK@2836|Bacillariophyta	2836|Bacillariophyta	L	DnaB-like helicase N terminal domain	dnaB	-	-	-	-	-	-	-	-	-	-	-	DnaB,DnaB_C
k141_5360_1	1229909.NSED_07185	3.76e-95	284.0	COG0189@1|root,arCOG01589@2157|Archaea,41SE8@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Lysine biosynthesis	-	-	6.3.2.43	ko:K05827	ko00300,ko01100,ko01210,ko01230,map00300,map01100,map01210,map01230	M00031	R09775	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	RimK
k141_7199_1	571166.KI421509_gene2762	7.71e-99	295.0	COG0583@1|root,COG0583@2|Bacteria,1N4P5@1224|Proteobacteria,2TQYX@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
k141_1657_1	1297570.MESS4_510114	3.35e-37	140.0	2DNRB@1|root,32YRN@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_1032_1	1288298.rosmuc_01953	1.13e-63	207.0	COG4949@1|root,COG4949@2|Bacteria,1MVI2@1224|Proteobacteria,2TSQJ@28211|Alphaproteobacteria,46QG4@74030|Roseovarius	28211|Alphaproteobacteria	S	Protein of unknown function (DUF3422)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3422
k141_2275_1	1123360.thalar_03016	2.08e-177	498.0	COG4927@1|root,COG4927@2|Bacteria,1MY0W@1224|Proteobacteria,2TTM1@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	choloylglycine hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	AAT
k141_2275_2	1268622.AVS7_02548	2.38e-19	87.4	COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,2VJJ6@28216|Betaproteobacteria,4AAE9@80864|Comamonadaceae	28216|Betaproteobacteria	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_3
k141_2965_1	45157.CMW021CT	8.45e-54	179.0	COG1005@1|root,KOG4770@2759|Eukaryota	2759|Eukaryota	C	NADH dehydrogenase (quinone) activity	ND1	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005746,GO:0005747,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0006996,GO:0007005,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009507,GO:0009536,GO:0009987,GO:0010033,GO:0010257,GO:0014070,GO:0015979,GO:0015980,GO:0016020,GO:0016043,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0019866,GO:0022607,GO:0022900,GO:0022904,GO:0030425,GO:0030964,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0032981,GO:0032991,GO:0033108,GO:0033194,GO:0034622,GO:0034641,GO:0036477,GO:0042221,GO:0042493,GO:0042773,GO:0042775,GO:0042995,GO:0043005,GO:0043025,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044281,GO:0044297,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044444,GO:0044446,GO:0044455,GO:0044463,GO:0044464,GO:0045271,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0050896,GO:0055086,GO:0055114,GO:0065003,GO:0070469,GO:0071704,GO:0071840,GO:0072521,GO:0097447,GO:0097458,GO:0098796,GO:0098798,GO:0098800,GO:0098803,GO:0120025,GO:0120038,GO:1901135,GO:1901360,GO:1901564,GO:1901700,GO:1902494,GO:1990204	1.6.5.3	ko:K03878,ko:K04257,ko:K05572,ko:K05579	ko00190,ko01100,ko04714,ko04723,ko04740,ko05012,map00190,map01100,map04714,map04723,map04740,map05012	M00142,M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000,ko03029,ko04030	3.D.1.6	-	-	Complex1_49kDa,NADHdh
k141_7271_1	1042326.AZNV01000025_gene505	1.69e-10	62.0	COG1651@1|root,COG1651@2|Bacteria,1RFF4@1224|Proteobacteria,2U5BN@28211|Alphaproteobacteria,4B74W@82115|Rhizobiaceae	28211|Alphaproteobacteria	O	COG1651 Protein-disulfide isomerase	MA20_42440	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_4
k141_7271_2	1122929.KB908223_gene2539	1.13e-28	113.0	COG2230@1|root,COG2230@2|Bacteria,1MX3U@1224|Proteobacteria,2TR8K@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	COG2230 Cyclopropane fatty acid synthase and related methyltransferases	cfa	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006629,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0008825,GO:0009987,GO:0016740,GO:0016741,GO:0030258,GO:0032259,GO:0044237,GO:0044238,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0071704	2.1.1.79	ko:K00574	-	-	-	-	ko00000,ko01000	-	-	-	CMAS
k141_2348_1	583355.Caka_1836	1.12e-84	274.0	COG0341@1|root,COG0342@1|root,COG0341@2|Bacteria,COG0342@2|Bacteria,46SA4@74201|Verrucomicrobia,3K770@414999|Opitutae	414999|Opitutae	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4	-	-	SecD_SecF,Sec_GG
k141_6450_2	44056.XP_009038339.1	1.37e-53	179.0	KOG1207@1|root,KOG1207@2759|Eukaryota	2759|Eukaryota	S	L-xylulose reductase (NAD+) activity	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
k141_894_1	1229909.NSED_09245	3.99e-93	275.0	COG0431@1|root,arCOG04624@2157|Archaea,41T2F@651137|Thaumarchaeota	651137|Thaumarchaeota	S	NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
k141_2746_1	1286106.MPL1_12391	1.73e-06	48.5	COG0073@1|root,COG0143@1|root,COG0073@2|Bacteria,COG0143@2|Bacteria,1MUBY@1224|Proteobacteria,1RMYM@1236|Gammaproteobacteria,45ZT6@72273|Thiotrichales	72273|Thiotrichales	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	-	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g,tRNA_bind
k141_2746_2	550540.Fbal_2235	3.03e-67	209.0	COG4657@1|root,COG4657@2|Bacteria,1MU8X@1224|Proteobacteria,1RQDN@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Part of a membrane complex involved in electron transport	rnfA	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0044464,GO:0055114,GO:0071944	-	ko:K03617	-	-	-	-	ko00000	-	-	-	Rnf-Nqr
k141_1512_1	333138.LQ50_21010	1.73e-28	115.0	COG0006@1|root,COG0006@2|Bacteria,1TSN0@1239|Firmicutes,4HCA3@91061|Bacilli,1ZAZR@1386|Bacillus	91061|Bacilli	E	Creatinase/Prolidase N-terminal domain	-	-	3.4.13.9	ko:K01271	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Creatinase_N,Peptidase_M24
k141_8869_1	571166.KI421509_gene2119	2.52e-82	261.0	COG2812@1|root,COG2812@2|Bacteria,1MVCK@1224|Proteobacteria,2TRPB@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3,DUF3646
k141_3976_1	1229909.NSED_06070	3.02e-45	150.0	arCOG08678@1|root,arCOG08678@2157|Archaea,41SR1@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_3976_2	1229909.NSED_06075	1.41e-21	85.9	arCOG10406@1|root,arCOG10406@2157|Archaea,41SVU@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Zinc finger, C2H2 type	-	-	-	-	-	-	-	-	-	-	-	-	zf-C2H2
k141_3976_3	436308.Nmar_1032	4.46e-17	73.2	COG1996@1|root,arCOG04341@2157|Archaea,41SWH@651137|Thaumarchaeota	651137|Thaumarchaeota	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	-	-	2.7.7.6	ko:K03059	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00184	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021	-	-	-	-
k141_9527_2	35128.Thaps34554	3.74e-55	174.0	2AR4E@1|root,2RMFI@2759|Eukaryota,2XGGX@2836|Bacillariophyta	2836|Bacillariophyta	U	Psb28 protein	-	-	-	ko:K08903	ko00195,ko01100,map00195,map01100	-	-	-	ko00000,ko00001,ko00194	-	-	-	Psb28
k141_2747_1	314264.ROS217_21692	9.11e-102	296.0	COG0231@1|root,COG0231@2|Bacteria,1MW2J@1224|Proteobacteria,2TUWE@28211|Alphaproteobacteria,46PNY@74030|Roseovarius	28211|Alphaproteobacteria	J	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase	efp	-	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
k141_7627_2	472759.Nhal_0785	2e-18	81.3	COG1394@1|root,COG1394@2|Bacteria,1PA1A@1224|Proteobacteria,1S17V@1236|Gammaproteobacteria,1WWE8@135613|Chromatiales	135613|Chromatiales	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	-	-	-	ko:K02120	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_D
k141_5219_2	159749.E7BWK8	3.1e-40	154.0	COG0542@1|root,KOG1051@2759|Eukaryota,2XEW9@2836|Bacillariophyta	2836|Bacillariophyta	O	Belongs to the ClpA ClpB family	-	-	-	-	-	-	-	-	-	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
k141_8259_1	398580.Dshi_1332	1.82e-75	243.0	COG0595@1|root,COG0595@2|Bacteria,1MUGV@1224|Proteobacteria,2TQTR@28211|Alphaproteobacteria	28211|Alphaproteobacteria	H	hydrolase of the metallo-beta-lactamase superfamily	rnjA	-	-	ko:K12574	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	Lactamase_B,Lactamase_B_2,RMMBL
k141_3978_1	713587.THITH_09765	8.45e-10	63.2	COG3055@1|root,COG5640@1|root,COG3055@2|Bacteria,COG5640@2|Bacteria	2|Bacteria	O	serine-type endopeptidase activity	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Calx-beta,PPC,Trypsin
k141_897_1	95619.PM1_0204980	1.81e-61	201.0	COG1466@1|root,COG1466@2|Bacteria,1MWYT@1224|Proteobacteria,1RQRE@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	dna polymerase III delta subunit	holA	GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0032991,GO:0034641,GO:0034645,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:1901360,GO:1901576,GO:1902494,GO:1990234	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delt_C,DNA_pol3_delta
k141_3351_1	396588.Tgr7_1282	1.5e-71	239.0	COG0249@1|root,COG0249@2|Bacteria,1MUGX@1224|Proteobacteria,1RNW3@1236|Gammaproteobacteria,1WVV0@135613|Chromatiales	135613|Chromatiales	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	mutS	-	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
k141_6453_1	269796.Rru_A3780	2.48e-50	171.0	COG2740@1|root,COG2740@2|Bacteria,1RHPR@1224|Proteobacteria,2U9RY@28211|Alphaproteobacteria,2JSPK@204441|Rhodospirillales	204441|Rhodospirillales	K	nucleic-acid-binding protein implicated in transcription termination	-	-	-	ko:K07742	-	-	-	-	ko00000	-	-	-	DUF448,Ribosomal_L7Ae
k141_6453_2	384765.SIAM614_02946	0.000221	44.3	COG0195@1|root,COG0195@2|Bacteria,1MWT7@1224|Proteobacteria,2TRQN@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	Participates in both transcription termination and antitermination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	HHH_5,KH_5,NusA_N,S1
k141_9529_1	861299.J421_3420	1.71e-51	177.0	COG0539@1|root,COG0539@2|Bacteria,1ZSKI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence	-	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
k141_1515_1	571166.KI421509_gene2166	2.79e-92	273.0	COG0066@1|root,COG0066@2|Bacteria,1MVXB@1224|Proteobacteria,2TRRS@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuD	-	4.2.1.33,4.2.1.35	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R10170	RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase_C
k141_5830_2	1335757.SPICUR_08290	7.84e-10	58.5	COG0050@1|root,COG0050@2|Bacteria,1MVC0@1224|Proteobacteria,1RMYX@1236|Gammaproteobacteria,1WWIK@135613|Chromatiales	135613|Chromatiales	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
k141_5221_1	1384056.N787_04715	2.29e-21	98.2	COG0501@1|root,COG0501@2|Bacteria,1MVU4@1224|Proteobacteria,1RPJ5@1236|Gammaproteobacteria,1X4SV@135614|Xanthomonadales	135614|Xanthomonadales	O	Peptidase M48 Ste24p	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
k141_5831_1	686340.Metal_1844	9.98e-84	275.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,1MV6G@1224|Proteobacteria,1RMYD@1236|Gammaproteobacteria,1XE0B@135618|Methylococcales	135618|Methylococcales	H	Vitamin B12 dependent methionine synthase, activation	metH	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
k141_283_1	2850.Phatr20331	4.43e-49	164.0	28JI2@1|root,2QRXA@2759|Eukaryota,2XA6Q@2836|Bacillariophyta	2836|Bacillariophyta	S	Manganese-stabilising protein / photosystem II polypeptide	PsbO	-	-	ko:K02716	ko00195,ko01100,map00195,map01100	-	-	-	ko00000,ko00001,ko00194	-	-	-	MSP
k141_2750_2	1198232.CYCME_2006	2.45e-74	231.0	COG4181@1|root,COG4181@2|Bacteria,1MXG9@1224|Proteobacteria,1RMG1@1236|Gammaproteobacteria,460G3@72273|Thiotrichales	72273|Thiotrichales	Q	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
k141_8944_1	999549.KI421513_gene1890	9.92e-66	210.0	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,2TQQ7@28211|Alphaproteobacteria,280Z5@191028|Leisingera	28211|Alphaproteobacteria	I	Thiolase, C-terminal domain	thlA	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
k141_4692_1	290512.Paes_0783	1.71e-08	62.0	COG1376@1|root,COG2304@1|root,COG2911@1|root,COG2931@1|root,COG3291@1|root,COG4932@1|root,COG5295@1|root,COG1376@2|Bacteria,COG2304@2|Bacteria,COG2911@2|Bacteria,COG2931@2|Bacteria,COG3291@2|Bacteria,COG4932@2|Bacteria,COG5295@2|Bacteria,1FETB@1090|Chlorobi	1090|Chlorobi	QUW	outer membrane adhesin like proteiin	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_2223_1	400682.PAC_15720214	3.29e-31	120.0	COG2801@1|root,KOG0017@2759|Eukaryota,3A5XY@33154|Opisthokonta,3C0JZ@33208|Metazoa	33154|Opisthokonta	L	transposition, RNA-mediated	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_6537_1	948106.AWZT01000015_gene658	7.87e-28	115.0	COG2391@1|root,COG2391@2|Bacteria,1PF9B@1224|Proteobacteria,2VKKD@28216|Betaproteobacteria,1K2C9@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Sulphur transport	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
k141_5306_1	35128.Thapsdraft598	1.25e-38	132.0	COG0711@1|root,2S8NX@2759|Eukaryota,2XFCS@2836|Bacillariophyta	2836|Bacillariophyta	C	ATP synthase subunit b', chloroplastic	atpG	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
k141_5916_1	985054.JQEZ01000003_gene1604	2.11e-66	222.0	COG1185@1|root,COG1185@2|Bacteria,1MVB9@1224|Proteobacteria,2TRH3@28211|Alphaproteobacteria,4N9RY@97050|Ruegeria	28211|Alphaproteobacteria	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	GO:0000175,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0004654,GO:0005488,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:0140098,GO:1901360,GO:1901361,GO:1901363,GO:1901575	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
k141_2834_1	426355.Mrad2831_1122	9.96e-82	255.0	COG0820@1|root,COG0820@2|Bacteria,1MUYK@1224|Proteobacteria,2TQT3@28211|Alphaproteobacteria,1JRAR@119045|Methylobacteriaceae	28211|Alphaproteobacteria	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Radical_SAM
k141_9601_1	37727.XP_002147152.1	1.69e-09	66.2	COG2801@1|root,KOG0017@2759|Eukaryota,38DPC@33154|Opisthokonta,3NUZ7@4751|Fungi,3QNZW@4890|Ascomycota,20FR9@147545|Eurotiomycetes,3SBAR@5042|Eurotiales	4751|Fungi	L	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	RVT_2,Retrotran_gag_2,gag_pre-integrs,rve,zf-CCHC
k141_2224_1	1116472.MGMO_37c00170	3.53e-63	202.0	COG4974@1|root,COG4974@2|Bacteria,1MVNF@1224|Proteobacteria,1RPI8@1236|Gammaproteobacteria,1XDWR@135618|Methylococcales	135618|Methylococcales	D	recombinase XerD	xerD	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
k141_5307_1	1249627.D779_0657	2.36e-55	179.0	COG2065@1|root,COG2065@2|Bacteria,1RI6U@1224|Proteobacteria,1S6WA@1236|Gammaproteobacteria,1WXPI@135613|Chromatiales	135613|Chromatiales	F	phosphoribosyltransferase	pyrR	-	2.4.2.9	ko:K02825	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000,ko03000	-	-	-	Pribosyltran
k141_7716_1	998674.ATTE01000001_gene2402	5.76e-109	322.0	COG4663@1|root,COG4663@2|Bacteria,1MVMD@1224|Proteobacteria,1RNCK@1236|Gammaproteobacteria,45ZWY@72273|Thiotrichales	72273|Thiotrichales	Q	Part of the tripartite ATP-independent periplasmic (TRAP) transport system	-	-	-	-	-	-	-	-	-	-	-	-	DctP
k141_8348_1	1380600.AUYN01000009_gene1366	2.04e-41	147.0	COG1262@1|root,COG1262@2|Bacteria,4NGY2@976|Bacteroidetes,1HXXN@117743|Flavobacteriia	976|Bacteroidetes	S	gliding motility-associated lipoprotein GldK	gldK	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
k141_5308_1	309801.trd_0634	4.5e-13	73.2	COG0631@1|root,COG0631@2|Bacteria,2G6R4@200795|Chloroflexi,27XZK@189775|Thermomicrobia	189775|Thermomicrobia	T	Serine/threonine phosphatases, family 2C, catalytic domain	-	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C
k141_370_1	373903.Hore_18890	2.4e-17	85.9	COG0859@1|root,COG1519@1|root,COG0859@2|Bacteria,COG1519@2|Bacteria,1TT7Z@1239|Firmicutes,24KS2@186801|Clostridia,3WCB0@53433|Halanaerobiales	186801|Clostridia	M	3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase)	-	-	2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15	ko:K02527	ko00540,ko01100,map00540,map01100	M00060,M00080	R04658,R05074,R09763	RC00009,RC00077,RC00247	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT30	-	Glyco_transf_9,Glycos_transf_N
k141_7152_1	909943.HIMB100_00014160	4.89e-98	296.0	COG1290@1|root,COG1290@2|Bacteria,1MV97@1224|Proteobacteria,2TSZ3@28211|Alphaproteobacteria,4BPD0@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	C	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis	petB	-	-	ko:K00412	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002,ko03029	-	-	-	Cytochrom_B_C,Cytochrome_B
k141_1603_1	1177154.Y5S_01705	4.08e-52	186.0	COG2885@1|root,COG2885@2|Bacteria,1QW22@1224|Proteobacteria,1T4AK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Ompa motb domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,OmpA
k141_4695_1	669008.D3W6A9_9CAUD	1.28e-05	50.4	4QCM5@10239|Viruses,4QVZY@35237|dsDNA viruses  no RNA stage,4QQFH@28883|Caudovirales,4QNDH@10744|Podoviridae	10744|Podoviridae	S	Bacteriophage head to tail connecting protein	-	GO:0005575,GO:0008150,GO:0016032,GO:0019012,GO:0019028,GO:0019058,GO:0019068,GO:0019072,GO:0019073,GO:0032991,GO:0044403,GO:0044419,GO:0044423,GO:0046798,GO:0051704	-	-	-	-	-	-	-	-	-	-	-
k141_8349_1	1249627.D779_0852	6.18e-33	130.0	COG4796@1|root,COG4796@2|Bacteria,1QTT6@1224|Proteobacteria,1RN3Z@1236|Gammaproteobacteria,1WWYN@135613|Chromatiales	135613|Chromatiales	U	type IV pilus secretin PilQ	-	-	-	ko:K02666	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	AMIN,STN,Secretin,Secretin_N
k141_5919_2	876044.IMCC3088_1278	2.58e-47	167.0	COG0297@1|root,COG0297@2|Bacteria,1MUGM@1224|Proteobacteria,1RNMP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	Synthesizes alpha-1,4-glucan chains using ADP-glucose	glgA	GO:0000271,GO:0003674,GO:0003824,GO:0004373,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008194,GO:0009011,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033554,GO:0033692,GO:0034637,GO:0034645,GO:0035251,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046527,GO:0050896,GO:0051716,GO:0055114,GO:0071704,GO:1901576	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	iSFV_1184.SFV_3438	Glyco_transf_5,Glycos_transf_1
k141_983_2	713586.KB900536_gene67	2.05e-35	129.0	COG0136@1|root,COG0136@2|Bacteria,1MUHG@1224|Proteobacteria,1RNB6@1236|Gammaproteobacteria,1WWMZ@135613|Chromatiales	135613|Chromatiales	E	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate	asd	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
k141_7718_1	159749.E7BWE1	2.82e-65	207.0	2CMAK@1|root,2QPT8@2759|Eukaryota,2XE9B@2836|Bacillariophyta	2836|Bacillariophyta	C	Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions	petA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009536,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464	-	ko:K02634	ko00195,ko01100,map00195,map01100	M00162	-	-	ko00000,ko00001,ko00002,ko00194	-	-	-	Apocytochr_F_C,Apocytochr_F_N
k141_2227_1	523791.Kkor_2515	4.77e-17	79.7	COG3245@1|root,COG3245@2|Bacteria,1MZBZ@1224|Proteobacteria,1S9Z9@1236|Gammaproteobacteria,1XKPZ@135619|Oceanospirillales	135619|Oceanospirillales	C	cytochrome c5	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
k141_4696_2	537011.PREVCOP_06140	2.78e-14	74.3	COG0097@1|root,COG0097@2|Bacteria,4NGJM@976|Bacteroidetes,2FNEG@200643|Bacteroidia	976|Bacteroidetes	J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center	rplF	GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02933	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L6
k141_1605_1	1244869.H261_12141	1.77e-19	92.8	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2TQS3@28211|Alphaproteobacteria,2JQE1@204441|Rhodospirillales	204441|Rhodospirillales	T	COG2202 FOG PAS PAC domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_3,PAS_9,Response_reg
k141_6542_2	1177928.TH2_19038	2.19e-64	205.0	COG2513@1|root,COG2513@2|Bacteria,1N4VT@1224|Proteobacteria,2TTP8@28211|Alphaproteobacteria,2JPB6@204441|Rhodospirillales	204441|Rhodospirillales	G	COG2513 PEP phosphonomutase and related enzymes	-	-	-	-	-	-	-	-	-	-	-	-	PEP_mutase
k141_3434_1	384765.SIAM614_02591	7.04e-216	607.0	COG3653@1|root,COG3653@2|Bacteria,1MWWY@1224|Proteobacteria,2TT5E@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	COG3653 N-acyl-D-aspartate D-glutamate deacylase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
k141_8351_1	1417296.U879_13720	3.12e-111	333.0	COG3039@1|root,COG3039@2|Bacteria,1MVTU@1224|Proteobacteria,2TVIR@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	hmm pf01609	-	-	-	ko:K07481	-	-	-	-	ko00000	-	-	-	DDE_Tnp_1,DUF772
k141_2229_1	37659.JNLN01000001_gene680	3.27e-44	148.0	COG0096@1|root,COG0096@2|Bacteria,1V3KK@1239|Firmicutes,24HCP@186801|Clostridia,36I6W@31979|Clostridiaceae	186801|Clostridia	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit	rpsH	-	-	ko:K02994	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S8
k141_7720_1	1131269.AQVV01000040_gene1637	5.17e-07	49.3	COG0100@1|root,COG0100@2|Bacteria	2|Bacteria	J	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome	rpsK	GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
k141_7720_2	1192868.CAIU01000012_gene1465	2.12e-46	154.0	COG0099@1|root,COG0099@2|Bacteria,1RD1G@1224|Proteobacteria,2U73D@28211|Alphaproteobacteria,43JTA@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	rpsM	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
k141_985_1	1158294.JOMI01000002_gene3155	2.89e-29	109.0	2DN97@1|root,32W7A@2|Bacteria,4P5E4@976|Bacteroidetes,2FTS2@200643|Bacteroidia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_9605_1	159749.E7BWM4	1.71e-15	75.5	COG0092@1|root,2QV63@2759|Eukaryota	2759|Eukaryota	J	structural constituent of ribosome	rps3	GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009295,GO:0009507,GO:0009526,GO:0009532,GO:0009536,GO:0009570,GO:0009941,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022626,GO:0022627,GO:0031967,GO:0031975,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02982	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KH_2,Ribosomal_S3_C
k141_374_1	2850.Phatrdraft1240	1.64e-31	126.0	COG2801@1|root,KOG0017@2759|Eukaryota,2XEGG@2836|Bacillariophyta	2836|Bacillariophyta	L	transposition, RNA-mediated	-	-	-	-	-	-	-	-	-	-	-	-	RVT_2,gag_pre-integrs,rve,zf-CCHC
k141_7721_1	441769.ABFU01000130_gene2342	7.86e-09	54.3	2EG8N@1|root,33A0G@2|Bacteria,1VMHK@1239|Firmicutes,4HSIH@91061|Bacilli,1ZJWT@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_6543_1	285535.JOEY01000049_gene1405	4.56e-38	146.0	COG1506@1|root,COG1506@2|Bacteria,2H90U@201174|Actinobacteria	201174|Actinobacteria	E	Tannase and feruloyl esterase	-	-	-	-	-	-	-	-	-	-	-	-	Tannase
k141_5923_1	158500.BV97_03964	3.54e-42	152.0	COG5323@1|root,COG5323@2|Bacteria,1MW8S@1224|Proteobacteria,2TREI@28211|Alphaproteobacteria,2K2BG@204457|Sphingomonadales	204457|Sphingomonadales	S	Terminase RNaseH-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Terminase_6,Terminase_6C
k141_8232_1	999550.KI421507_gene2654	5.49e-111	345.0	COG0243@1|root,COG3383@1|root,COG0243@2|Bacteria,COG3383@2|Bacteria,1MW3N@1224|Proteobacteria,2TTPX@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	fdhF	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
k141_252_1	498211.CJA_1448	8.37e-68	223.0	COG0260@1|root,COG0260@2|Bacteria,1MUF9@1224|Proteobacteria,1RNM1@1236|Gammaproteobacteria,1FGHX@10|Cellvibrio	1236|Gammaproteobacteria	E	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides	pepA	GO:0001073,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0004177,GO:0005488,GO:0006139,GO:0006259,GO:0006276,GO:0006310,GO:0006351,GO:0006355,GO:0006508,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0009056,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016787,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019538,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0042150,GO:0043170,GO:0043171,GO:0043244,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:0140096,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1903506,GO:2000112,GO:2001141	3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17,Peptidase_M17_N
k141_5801_1	159749.E7BWJ3	1.9e-200	573.0	28JJ8@1|root,2QRYE@2759|Eukaryota	2759|Eukaryota	C	chlorophyll binding	psaA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009534,GO:0009535,GO:0009536,GO:0009579,GO:0016020,GO:0031976,GO:0031984,GO:0034357,GO:0042651,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044436,GO:0044444,GO:0044446,GO:0044464,GO:0055035	-	ko:K02689,ko:K02690	ko00195,ko01100,map00195,map01100	M00163	-	-	ko00000,ko00001,ko00002,ko00194	-	-	-	PsaA_PsaB
k141_2723_3	251229.Chro_4104	3.17e-47	175.0	COG0653@1|root,COG0653@2|Bacteria,1G1B4@1117|Cyanobacteria,3VID3@52604|Pleurocapsales	1117|Cyanobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	SecA_DEAD,SecA_PP_bind,SecA_SW
k141_7604_1	159749.K0TDD2	1.22e-79	275.0	COG2801@1|root,KOG3098@1|root,KOG0017@2759|Eukaryota,KOG3098@2759|Eukaryota	2759|Eukaryota	S	G-protein coupled peptide receptor activity	-	GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0022857,GO:0051179,GO:0051234,GO:0055085	-	-	-	-	-	-	-	-	-	-	MFS_1,UNC-93
k141_6431_1	620914.JH621255_gene646	3.08e-133	414.0	COG0308@1|root,COG1277@1|root,COG0308@2|Bacteria,COG1277@2|Bacteria,4NF3R@976|Bacteroidetes,1HXJJ@117743|Flavobacteriia,2YHGR@290174|Aquimarina	976|Bacteroidetes	E	ABC-2 family transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_4,Peptidase_M1
k141_3951_1	1297742.A176_05092	9.73e-30	112.0	COG2801@1|root,COG2801@2|Bacteria,1MVXQ@1224|Proteobacteria,42M98@68525|delta/epsilon subdivisions,2WMKB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	PFAM Integrase catalytic	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,HTH_Tnp_1,rve,rve_3
k141_7042_1	2850.Phatr47497	8.08e-36	143.0	2EIR5@1|root,2SP3H@2759|Eukaryota,2XFGP@2836|Bacillariophyta	2836|Bacillariophyta	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_5802_1	1538644.KO02_04330	8.81e-07	54.7	COG4977@1|root,COG4977@2|Bacteria,4NHTS@976|Bacteroidetes,1IPXZ@117747|Sphingobacteriia	976|Bacteroidetes	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
k141_5193_1	1237149.C900_03483	2.78e-64	204.0	COG0101@1|root,COG0101@2|Bacteria,4NFDC@976|Bacteroidetes,47KUM@768503|Cytophagia	976|Bacteroidetes	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
k141_7605_1	1163408.UU9_14345	3.05e-18	89.0	COG0706@1|root,COG0706@2|Bacteria,1MV5M@1224|Proteobacteria,1RMH1@1236|Gammaproteobacteria,1X497@135614|Xanthomonadales	135614|Xanthomonadales	U	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins	yidC	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP,YidC_periplas
k141_254_1	1229909.NSED_01640	3.3e-103	308.0	COG1104@1|root,arCOG00066@2157|Archaea,41SB1@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Cysteine desulfurase	-	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
k141_6432_1	35128.Thapsdraft989	4.27e-19	80.5	COG0268@1|root,2R9BJ@2759|Eukaryota,2XH98@2836|Bacillariophyta	2836|Bacillariophyta	J	Binds directly to 16S ribosomal RNA	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009536,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464	-	-	-	-	-	-	-	-	-	-	Ribosomal_S20p
k141_2111_1	1380394.JADL01000001_gene2244	2.24e-29	123.0	COG1529@1|root,COG1529@2|Bacteria,1QTTJ@1224|Proteobacteria,2TQVK@28211|Alphaproteobacteria,2JPB3@204441|Rhodospirillales	204441|Rhodospirillales	C	COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs	-	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
k141_3952_1	1336803.PHEL49_0763	5.94e-138	402.0	COG0471@1|root,COG0471@2|Bacteria,4NFDK@976|Bacteroidetes,1HX3U@117743|Flavobacteriia,3VV80@52959|Polaribacter	976|Bacteroidetes	P	Di- and tricarboxylate transporters	-	-	-	ko:K14445	-	-	-	-	ko00000,ko02000	2.A.47.1	-	-	Na_sulph_symp
k141_9505_1	1122603.ATVI01000005_gene3810	1.72e-48	166.0	COG0583@1|root,COG0583@2|Bacteria,1MXRP@1224|Proteobacteria,1RQP1@1236|Gammaproteobacteria,1X9YV@135614|Xanthomonadales	135614|Xanthomonadales	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
k141_876_1	187272.Mlg_2591	8.2e-112	337.0	COG1866@1|root,COG1866@2|Bacteria,1MWXN@1224|Proteobacteria,1RPM0@1236|Gammaproteobacteria,1WWJT@135613|Chromatiales	135613|Chromatiales	H	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA	pckA	-	4.1.1.49	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00170	R00341	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPCK_ATP
k141_8236_1	1205908.AKXW01000020_gene1085	6.94e-107	317.0	COG2801@1|root,COG2801@2|Bacteria,1PBHA@1224|Proteobacteria,1RQ7I@1236|Gammaproteobacteria,1XSS2@135623|Vibrionales	135623|Vibrionales	L	Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_32,rve,rve_3
k141_2112_1	35128.Thapsdraft573	1.59e-161	458.0	2CMAK@1|root,2QPT8@2759|Eukaryota,2XE9B@2836|Bacillariophyta	2836|Bacillariophyta	C	Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions	petA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009536,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464	-	ko:K02634	ko00195,ko01100,map00195,map01100	M00162	-	-	ko00000,ko00001,ko00002,ko00194	-	-	-	Apocytochr_F_C,Apocytochr_F_N
k141_5196_1	1121022.ABENE_21950	7.32e-73	229.0	COG3547@1|root,COG3547@2|Bacteria,1MUER@1224|Proteobacteria,2TSGZ@28211|Alphaproteobacteria,2KHQT@204458|Caulobacterales	204458|Caulobacterales	L	PFAM transposase IS116 IS110 IS902 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k141_3326_1	998674.ATTE01000001_gene3030	1.27e-57	186.0	COG4849@1|root,COG4849@2|Bacteria,1RDHG@1224|Proteobacteria,1S125@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	AbiEii
k141_9507_1	83406.HDN1F_32740	1.87e-31	117.0	COG0776@1|root,COG0776@2|Bacteria,1RFWH@1224|Proteobacteria,1S5GE@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Belongs to the bacterial histone-like protein family	VL23_14575	-	-	-	-	-	-	-	-	-	-	-	Bac_DNA_binding
k141_1492_1	429009.Adeg_0212	1.16e-35	126.0	COG0103@1|root,COG0103@2|Bacteria,1V3MQ@1239|Firmicutes,24H94@186801|Clostridia,42G8M@68295|Thermoanaerobacterales	186801|Clostridia	J	Belongs to the universal ribosomal protein uS9 family	rpsI	-	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
k141_1492_2	864702.OsccyDRAFT_3413	7.06e-27	106.0	COG0102@1|root,COG0102@2|Bacteria,1G512@1117|Cyanobacteria,1HAJM@1150|Oscillatoriales	1117|Cyanobacteria	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rplM	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
k141_1492_3	1128427.KB904821_gene4435	4.97e-94	289.0	COG0202@1|root,COG0202@2|Bacteria,1G094@1117|Cyanobacteria,1H8WH@1150|Oscillatoriales	1117|Cyanobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
k141_5806_1	1469613.JT55_07230	1.79e-52	174.0	COG1346@1|root,COG1346@2|Bacteria,1MV81@1224|Proteobacteria,2TSP3@28211|Alphaproteobacteria,3FDAJ@34008|Rhodovulum	28211|Alphaproteobacteria	M	LrgB-like family	lrgB	-	-	-	-	-	-	-	-	-	-	-	LrgB
k141_7608_1	314264.ROS217_09170	2.78e-97	295.0	COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,2TQW5@28211|Alphaproteobacteria,46QKT@74030|Roseovarius	28211|Alphaproteobacteria	G	COG1593 TRAP-type C4-dicarboxylate transport system, large permease component	-	-	-	-	-	-	-	-	-	-	-	-	DctM
k141_7047_1	443143.GM18_0341	1.79e-47	169.0	COG2133@1|root,COG2133@2|Bacteria,1NRFC@1224|Proteobacteria,42YAV@68525|delta/epsilon subdivisions,2WTUF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_2115_1	1265503.KB905164_gene1804	5.38e-51	178.0	COG1524@1|root,COG1524@2|Bacteria,1R5V5@1224|Proteobacteria,1S06C@1236|Gammaproteobacteria,2Q7GQ@267889|Colwelliaceae	1236|Gammaproteobacteria	S	Type I phosphodiesterase / nucleotide pyrophosphatase	pafA	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
k141_9509_1	243233.MCA2013	3.39e-44	157.0	COG0442@1|root,COG0442@2|Bacteria,1MU7E@1224|Proteobacteria,1RN5R@1236|Gammaproteobacteria,1XDV1@135618|Methylococcales	135618|Methylococcales	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS	proS	-	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_edit
k141_5199_1	1197477.IA57_11320	5.88e-66	226.0	2DC13@1|root,2ZCBS@2|Bacteria,4NMSX@976|Bacteroidetes,1I1WF@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_8238_1	247634.GPB2148_1518	2.96e-116	339.0	COG0016@1|root,COG0016@2|Bacteria,1MVD7@1224|Proteobacteria,1RN22@1236|Gammaproteobacteria,1J559@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily	pheS	GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iJN746.PP_2469	Phe_tRNA-synt_N,tRNA-synt_2d
k141_2729_1	398580.Dshi_3430	1.14e-66	206.0	COG4567@1|root,COG4567@2|Bacteria,1RD7J@1224|Proteobacteria,2TSK7@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain	regA	GO:0000156,GO:0000160,GO:0003674,GO:0007154,GO:0007165,GO:0008150,GO:0009987,GO:0023052,GO:0035556,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0060089,GO:0065007	-	ko:K15012	ko02020,map02020	M00523	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg
k141_2729_2	1423144.Gal_03608	1.11e-16	76.6	COG1896@1|root,COG1896@2|Bacteria,1RACF@1224|Proteobacteria,2TUK3@28211|Alphaproteobacteria,34ES1@302485|Phaeobacter	28211|Alphaproteobacteria	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	MA20_42120	-	-	ko:K06952	-	-	-	-	ko00000	-	-	-	HD,HD_3
k141_260_1	159749.K0T6U0	2.94e-48	174.0	COG2801@1|root,2QT1S@2759|Eukaryota	2759|Eukaryota	L	transposition	-	-	-	-	-	-	-	-	-	-	-	-	RVT_1,rve
k141_9510_1	977880.RALTA_A1991	1.04e-68	216.0	COG1028@1|root,COG1028@2|Bacteria,1MUS7@1224|Proteobacteria,2VM6S@28216|Betaproteobacteria,1K3I3@119060|Burkholderiaceae	28216|Betaproteobacteria	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	abmB	GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0010130,GO:0016043,GO:0016491,GO:0016614,GO:0016616,GO:0018913,GO:0018915,GO:0022607,GO:0042537,GO:0043933,GO:0044085,GO:0044237,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:1901360	1.1.1.30	ko:K00019,ko:K07535	ko00072,ko00362,ko00650,ko01100,ko01120,ko01220,map00072,map00362,map00650,map01100,map01120,map01220	M00088,M00540	R01361,R05582	RC00117,RC00154	ko00000,ko00001,ko00002,ko01000	-	-	-	adh_short,adh_short_C2
k141_7610_1	388401.RB2150_05848	8.37e-128	377.0	COG3333@1|root,COG3333@2|Bacteria,1MUKR@1224|Proteobacteria,2TR4Q@28211|Alphaproteobacteria,3ZGWC@58840|unclassified Rhodobacteraceae	28211|Alphaproteobacteria	S	Tripartite tricarboxylate transporter TctA family	-	-	-	ko:K07793	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.80.1	-	-	TctA
k141_7049_1	985255.APHJ01000021_gene1328	1.9e-17	83.2	COG0589@1|root,COG0589@2|Bacteria,4NFZ5@976|Bacteroidetes,1HYE4@117743|Flavobacteriia,2P5I4@244698|Gillisia	976|Bacteroidetes	T	Universal stress protein family	uspA	-	-	-	-	-	-	-	-	-	-	-	Usp
k141_261_2	272942.RCAP_rcc01392	1.74e-11	63.5	COG3191@1|root,COG3191@2|Bacteria,1MWDP@1224|Proteobacteria,2TUI2@28211|Alphaproteobacteria	28211|Alphaproteobacteria	EQ	L-aminopeptidase D-esterase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S58
k141_3957_1	1415756.JQMY01000005_gene3	2.45e-19	78.6	COG3293@1|root,COG3293@2|Bacteria	2|Bacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4096
k141_3957_2	314270.RB2083_3739	5.87e-61	190.0	COG0309@1|root,COG0309@2|Bacteria,1RDJ4@1224|Proteobacteria,2U7HE@28211|Alphaproteobacteria,3ZIJ7@58840|unclassified Rhodobacteraceae	28211|Alphaproteobacteria	O	L COG3293 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_2
k141_329_1	930945.SiRe_0211	4.81e-42	159.0	COG1233@1|root,arCOG01521@2157|Archaea,2XRK8@28889|Crenarchaeota	28889|Crenarchaeota	Q	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase,DAO
k141_5264_1	35128.Thapsdraft1611	1.86e-218	619.0	28JJ8@1|root,2QRYE@2759|Eukaryota,2XEB4@2836|Bacillariophyta	2836|Bacillariophyta	C	PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX. PSI is a plastocyanin cytochrome c6-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn. Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin or cytochrome c6	psaB	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009534,GO:0009535,GO:0009536,GO:0009579,GO:0016020,GO:0016168,GO:0031976,GO:0031984,GO:0034357,GO:0042651,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044436,GO:0044444,GO:0044446,GO:0044464,GO:0046906,GO:0048037,GO:0055035,GO:0097159,GO:1901363	-	ko:K02690	ko00195,ko01100,map00195,map01100	M00163	-	-	ko00000,ko00001,ko00002,ko00194	-	-	-	PsaA_PsaB
k141_4027_1	1232683.ADIMK_0681	9.68e-47	165.0	COG0031@1|root,COG0031@2|Bacteria,1MUBE@1224|Proteobacteria,1RN6J@1236|Gammaproteobacteria,4641I@72275|Alteromonadaceae	1236|Gammaproteobacteria	E	Belongs to the cysteine synthase cystathionine beta- synthase family	cysK	-	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	Glutaredoxin,PALP
k141_7108_1	159749.K0S6F1	1.35e-61	214.0	COG2801@1|root,KOG0017@2759|Eukaryota,2XEDA@2836|Bacillariophyta	2836|Bacillariophyta	L	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	RVT_2
k141_943_1	504487.JCM19302_2551	7.69e-26	99.0	COG0858@1|root,COG0858@2|Bacteria,4NSQJ@976|Bacteroidetes,1I2VE@117743|Flavobacteriia	976|Bacteroidetes	J	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA	rbfA	-	-	ko:K02834	-	-	-	-	ko00000,ko03009	-	-	-	RBFA
k141_943_2	504487.JCM19302_2552	3.44e-26	100.0	COG0346@1|root,COG0346@2|Bacteria,4NNGG@976|Bacteroidetes,1I1YS@117743|Flavobacteriia	976|Bacteroidetes	E	Glyoxalase bleomycin resistance protein dioxygenase	mce	-	5.1.99.1	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R02765,R09979	RC00780,RC02739	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase_4
k141_2185_1	1123360.thalar_02575	1.37e-13	73.2	COG0765@1|root,COG0765@2|Bacteria,1MV3I@1224|Proteobacteria,2TR9C@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	ABC-type amino acid transport system permease component	bztC	-	-	ko:K09971	ko02010,map02010	M00232	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3.18,3.A.1.3.7,3.A.1.3.8	-	-	BPD_transp_1
k141_7675_1	1265313.HRUBRA_01226	2.85e-74	236.0	COG0635@1|root,COG0635@2|Bacteria,1MU76@1224|Proteobacteria,1RN6I@1236|Gammaproteobacteria,1J4XU@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	H	Involved in the biosynthesis of porphyrin-containing compound	yggW	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
k141_5266_1	1469245.JFBG01000067_gene4	8.05e-116	344.0	COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,1RNAM@1236|Gammaproteobacteria,1WWRM@135613|Chromatiales	135613|Chromatiales	G	PFAM TRAP C4-dicarboxylate transport system permease DctM subunit	-	-	-	-	-	-	-	-	-	-	-	-	DctM
k141_2187_1	998674.ATTE01000001_gene3489	6.4e-80	259.0	COG0187@1|root,COG0187@2|Bacteria,1MVKT@1224|Proteobacteria,1RNB2@1236|Gammaproteobacteria,45ZT1@72273|Thiotrichales	72273|Thiotrichales	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
k141_2795_1	207954.MED92_07796	3.6e-104	313.0	COG0621@1|root,COG0621@2|Bacteria,1MURS@1224|Proteobacteria,1RMD8@1236|Gammaproteobacteria,1XHQS@135619|Oceanospirillales	135619|Oceanospirillales	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
k141_5878_1	583355.Caka_2856	2.73e-89	267.0	COG0528@1|root,COG0528@2|Bacteria,46S4W@74201|Verrucomicrobia,3K7UI@414999|Opitutae	414999|Opitutae	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	-	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
k141_5878_2	583355.Caka_2855	0.000147	43.1	COG0233@1|root,COG0233@2|Bacteria,46SVT@74201|Verrucomicrobia,3K7EG@414999|Opitutae	414999|Opitutae	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	-	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
k141_332_1	1026882.MAMP_00796	2.24e-74	243.0	COG5000@1|root,COG5000@2|Bacteria,1MWKZ@1224|Proteobacteria,1RQ8B@1236|Gammaproteobacteria,4604X@72273|Thiotrichales	72273|Thiotrichales	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4
k141_7676_1	159749.K0S5M3	7.77e-19	92.8	2D2UX@1|root,2SP3U@2759|Eukaryota,2XG67@2836|Bacillariophyta	2836|Bacillariophyta	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_6504_1	164328.Phyra75833	1.22e-18	99.4	COG2801@1|root,KOG0017@2759|Eukaryota,3Q8Z1@4776|Peronosporales	164328.Phyra75833|-	L	transposition, RNA-mediated	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_945_1	1282362.AEAC466_21675	1.92e-53	177.0	COG3039@1|root,COG3039@2|Bacteria,1MVDK@1224|Proteobacteria,2TS7B@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DUF772
k141_4532_1	1122201.AUAZ01000024_gene831	7.8e-35	122.0	COG0789@1|root,COG0789@2|Bacteria,1RGYB@1224|Proteobacteria,1S6Y1@1236|Gammaproteobacteria,467A4@72275|Alteromonadaceae	1236|Gammaproteobacteria	K	helix_turn_helix, mercury resistance	VL23_01195	-	-	-	-	-	-	-	-	-	-	-	MerR_1
k141_210_2	195105.CN97_09505	1.16e-51	172.0	COG2264@1|root,COG2264@2|Bacteria,1MUPC@1224|Proteobacteria,2TTP3@28211|Alphaproteobacteria	28211|Alphaproteobacteria	J	Ribosomal protein L11 methyltransferase	prmA	-	-	ko:K02687	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PrmA
k141_6998_1	159749.E7BWN0	1.38e-115	336.0	COG0094@1|root,KOG0398@2759|Eukaryota	2759|Eukaryota	J	structural constituent of ribosome	rpl5	GO:0000027,GO:0000313,GO:0000315,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005761,GO:0005762,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009507,GO:0009536,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0031974,GO:0032543,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070013,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:0098798,GO:0140053,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02931	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L5,Ribosomal_L5_C
k141_6998_2	489825.LYNGBM3L_71940	1.32e-52	169.0	COG0096@1|root,COG0096@2|Bacteria,1G5RQ@1117|Cyanobacteria,1HB6K@1150|Oscillatoriales	1117|Cyanobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit	rps8	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02994	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S8
k141_8873_1	913325.N799_07555	3.7e-70	219.0	COG1192@1|root,COG1192@2|Bacteria,1MV43@1224|Proteobacteria,1RNJK@1236|Gammaproteobacteria,1X30T@135614|Xanthomonadales	135614|Xanthomonadales	D	chromosome partitioning	parA	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
k141_3980_1	1207063.P24_10765	5e-64	204.0	COG0854@1|root,COG0854@2|Bacteria,1MU9W@1224|Proteobacteria,2TTTF@28211|Alphaproteobacteria,2JPM4@204441|Rhodospirillales	204441|Rhodospirillales	H	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate	pdxJ	-	2.6.99.2	ko:K03474	ko00750,ko01100,map00750,map01100	M00124	R05838	RC01476	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxJ
k141_3980_2	1238182.C882_3821	3.91e-13	65.1	COG0736@1|root,COG0736@2|Bacteria,1MZBF@1224|Proteobacteria,2U77S@28211|Alphaproteobacteria,2JSR7@204441|Rhodospirillales	204441|Rhodospirillales	I	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein	acpS	-	2.7.8.7	ko:K00997	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	-	ACPS
k141_4605_1	35128.Thapsdraft598	1.41e-28	107.0	COG0711@1|root,2S8NX@2759|Eukaryota,2XFCS@2836|Bacillariophyta	2836|Bacillariophyta	C	ATP synthase subunit b', chloroplastic	atpG	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
k141_4605_2	159749.E7BWI7	1.22e-70	218.0	2CZSM@1|root,2SBID@2759|Eukaryota,2XFN0@2836|Bacillariophyta	2836|Bacillariophyta	C	ATP synthase subunit b', chloroplastic	atpF	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
k141_899_1	159749.E7BWJ7	6.71e-53	175.0	COG0583@1|root,2S17Z@2759|Eukaryota	2759|Eukaryota	K	DNA-binding transcription factor activity	rbcR	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009536,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
k141_2751_1	1123267.JONN01000001_gene900	4.94e-70	230.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,1NBSJ@1224|Proteobacteria,2TU21@28211|Alphaproteobacteria,2K2JW@204457|Sphingomonadales	204457|Sphingomonadales	C	COG1014 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases, gamma subunit	-	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR,POR_N
k141_3981_1	1458275.AZ34_13810	1.45e-13	71.6	COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,2VHAN@28216|Betaproteobacteria,4AARD@80864|Comamonadaceae	28216|Betaproteobacteria	V	ABC transporter, transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
k141_5832_1	2850.Phatrdraft1240	1.07e-26	116.0	COG2801@1|root,KOG0017@2759|Eukaryota,2XEGG@2836|Bacillariophyta	2836|Bacillariophyta	L	transposition, RNA-mediated	-	-	-	-	-	-	-	-	-	-	-	-	RVT_2,gag_pre-integrs,rve,zf-CCHC
k141_6456_1	4096.XP_009796499.1	4.96e-05	46.2	COG2801@1|root,KOG0017@2759|Eukaryota,37SNQ@33090|Viridiplantae,3GHRQ@35493|Streptophyta	35493|Streptophyta	L	spliceosomal complex assembly	-	-	-	-	-	-	-	-	-	-	-	-	RVT_2
k141_2752_1	391613.RTM1035_05705	8.58e-16	75.9	COG1894@1|root,COG1905@1|root,COG1894@2|Bacteria,COG1905@2|Bacteria,1MV8F@1224|Proteobacteria,2TR1V@28211|Alphaproteobacteria,46PSW@74030|Roseovarius	28211|Alphaproteobacteria	C	COG1905 NADH ubiquinone oxidoreductase 24 kD subunit	nuoEF	-	1.17.1.9	ko:K00122	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	2Fe-2S_thioredx,Complex1_51K,NADH_4Fe-4S,SLBB
k141_2752_2	1123360.thalar_03599	7.48e-63	214.0	COG3383@1|root,COG3383@2|Bacteria,1QTZB@1224|Proteobacteria,2TVZI@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Formate dehydrogenase, alpha subunit	fdhA	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Fer2_4,Fer4,Fer4_7,Fer4_9,Molybdop_Fe4S4,Molybdopterin,Molydop_binding
k141_5224_1	377629.TERTU_3395	1.58e-16	78.6	COG0491@1|root,COG0491@2|Bacteria,1MX4H@1224|Proteobacteria,1RYRB@1236|Gammaproteobacteria,2PN5K@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
k141_5224_2	227377.CBU_0103	9.82e-37	136.0	COG0624@1|root,COG0624@2|Bacteria,1MW20@1224|Proteobacteria,1RPN7@1236|Gammaproteobacteria,1JD6Y@118969|Legionellales	118969|Legionellales	E	Peptidase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
k141_8263_1	518766.Rmar_2595	4.27e-42	149.0	COG0409@1|root,COG0409@2|Bacteria,4NIM8@976|Bacteroidetes	976|Bacteroidetes	O	TIGRFAM hydrogenase expression formation protein HypD	-	-	-	ko:K04654	-	-	-	-	ko00000	-	-	-	HypD
k141_8263_2	497965.Cyan7822_0635	6.51e-07	50.8	COG0309@1|root,COG0309@2|Bacteria,1G1Z7@1117|Cyanobacteria,3KGV9@43988|Cyanothece	1117|Cyanobacteria	O	hydrogenase expression formation protein HypE	hypE	-	-	ko:K04655	-	-	-	-	ko00000	-	-	-	AIRS,AIRS_C
k141_285_1	488538.SAR116_2173	6.84e-140	418.0	COG0404@1|root,COG0665@1|root,COG0404@2|Bacteria,COG0665@2|Bacteria,1MUXJ@1224|Proteobacteria,2TRGS@28211|Alphaproteobacteria,4BR7M@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	C	Belongs to the GcvT family	-	-	1.5.8.4	ko:K00315	ko00260,ko01100,map00260,map01100	-	R01565	RC00181	ko00000,ko00001,ko01000	-	-	-	DAO,FAO_M,GCV_T,GCV_T_C
k141_6457_1	314345.SPV1_01822	1.12e-91	273.0	COG2020@1|root,COG2020@2|Bacteria,1R7G6@1224|Proteobacteria	1224|Proteobacteria	O	Methyl-transferase	-	-	-	-	-	-	-	-	-	-	-	-	ICMT,PEMT
k141_2753_1	316057.RPD_1049	1.73e-16	79.0	COG1454@1|root,COG1454@2|Bacteria,1MVPH@1224|Proteobacteria,2TUHD@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	alcohol dehydrogenase	-	-	1.1.1.1	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	Fe-ADH
k141_3354_1	323261.Noc_0676	3.07e-88	266.0	COG0745@1|root,COG0745@2|Bacteria,1MVCB@1224|Proteobacteria,1RMW7@1236|Gammaproteobacteria,1WYD3@135613|Chromatiales	135613|Chromatiales	K	PFAM Response regulator receiver domain	-	-	-	ko:K07662	ko01503,ko02020,map01503,map02020	M00447,M00727,M00728	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
k141_7634_1	1166130.H650_16415	2.42e-12	61.2	2EG3W@1|root,339VW@2|Bacteria,1NHIR@1224|Proteobacteria,1SGXB@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_903_1	1116472.MGMO_1c00010	1.25e-53	189.0	COG0823@1|root,COG2815@1|root,COG3209@1|root,COG3291@1|root,COG0823@2|Bacteria,COG2815@2|Bacteria,COG3209@2|Bacteria,COG3291@2|Bacteria,1QXQ7@1224|Proteobacteria,1T3G4@1236|Gammaproteobacteria,1XGBG@135618|Methylococcales	135618|Methylococcales	M	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	-	-	-	-	-	-	-	-	-	-	-	-	REJ
k141_1521_1	345341.KUTG_06451	1.11e-12	70.5	COG2267@1|root,COG2267@2|Bacteria,2II4K@201174|Actinobacteria,4EFDB@85010|Pseudonocardiales	201174|Actinobacteria	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4,Abhydrolase_6
k141_287_2	1265505.ATUG01000002_gene1518	5.42e-09	57.4	COG3604@1|root,COG3604@2|Bacteria,1QTT3@1224|Proteobacteria,42Y50@68525|delta/epsilon subdivisions,2WUBF@28221|Deltaproteobacteria,2MPKM@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HTH_8,Sigma54_activat
k141_8876_1	595460.RRSWK_01544	2.7e-100	323.0	COG0086@1|root,COG0086@2|Bacteria,2IXGN@203682|Planctomycetes	203682|Planctomycetes	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
k141_1522_1	1336235.JAEG01000001_gene2541	4.38e-36	131.0	COG1496@1|root,COG1496@2|Bacteria,1MW2H@1224|Proteobacteria,2TTXU@28211|Alphaproteobacteria,4B8QV@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Belongs to the multicopper oxidase YfiH RL5 family	yfiH	-	-	ko:K05810	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase_4
k141_3986_1	1415779.JOMH01000001_gene3284	1.65e-121	361.0	COG0843@1|root,COG0843@2|Bacteria,1MU7S@1224|Proteobacteria,1RPC3@1236|Gammaproteobacteria,1X34C@135614|Xanthomonadales	135614|Xanthomonadales	C	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B	ctaD	-	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
k141_2756_1	555778.Hneap_1843	2.2e-25	105.0	COG5008@1|root,COG5008@2|Bacteria,1QTTX@1224|Proteobacteria,1RN0B@1236|Gammaproteobacteria,1WX4M@135613|Chromatiales	135613|Chromatiales	NU	PFAM Type II secretion system protein E	-	-	-	ko:K02670	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
k141_2756_2	713586.KB900536_gene1707	0.000113	44.7	COG5008@1|root,COG5008@2|Bacteria,1QTTX@1224|Proteobacteria,1RN0B@1236|Gammaproteobacteria,1WX16@135613|Chromatiales	135613|Chromatiales	NU	PFAM Type II secretion system protein E	-	-	-	ko:K02670	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
k141_9537_1	765911.Thivi_4139	2.57e-98	300.0	COG0312@1|root,COG0312@2|Bacteria,1MUSK@1224|Proteobacteria,1RMA5@1236|Gammaproteobacteria,1WWCQ@135613|Chromatiales	1224|Proteobacteria	S	modulator of DNA gyrase	tldD	-	-	ko:K03568	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
k141_7637_1	159749.K0TQC7	1.94e-33	130.0	COG2801@1|root,KOG0017@2759|Eukaryota,2XF4I@2836|Bacillariophyta	159749.K0TQC7|-	L	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_2146_1	395019.Bmul_3313	8.91e-88	268.0	COG0491@1|root,COG0607@1|root,COG0491@2|Bacteria,COG0607@2|Bacteria,1MURA@1224|Proteobacteria,2VJYK@28216|Betaproteobacteria,1K220@119060|Burkholderiaceae	28216|Betaproteobacteria	P	PFAM beta-lactamase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B,Rhodanese
k141_906_2	61273.S3D8L6	4.82e-12	66.2	COG1051@1|root,2S3YT@2759|Eukaryota,3A6H4@33154|Opisthokonta,3P493@4751|Fungi,3QXRC@4890|Ascomycota,21AV8@147550|Sordariomycetes,3UTS4@5151|Ophiostomatales	4751|Fungi	G	NUDIX domain	-	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
k141_7069_1	159749.K0RL31	9.42e-127	406.0	COG2801@1|root,KOG0017@2759|Eukaryota,2XF4I@2836|Bacillariophyta	159749.K0RL31|-	L	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_5838_1	1324957.K933_14288	5.98e-21	95.1	COG3380@1|root,arCOG04623@2157|Archaea,2XUDY@28890|Euryarchaeota,23RZA@183963|Halobacteria	183963|Halobacteria	S	NAD FAD-dependent oxidoreductase	-	-	-	ko:K06955	-	-	-	-	ko00000	-	-	-	Amino_oxidase,NAD_binding_8
k141_1524_1	1245471.PCA10_24130	2.66e-18	79.3	2CIMK@1|root,32S89@2|Bacteria,1N0NJ@1224|Proteobacteria,1S9BM@1236|Gammaproteobacteria,1YGKX@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	S	Protein of unknown function (DUF3302)	yiaW	-	-	-	-	-	-	-	-	-	-	-	DUF3302
k141_1524_2	458817.Shal_0926	2.56e-45	156.0	COG1566@1|root,COG1566@2|Bacteria,1NAMI@1224|Proteobacteria,1RP4N@1236|Gammaproteobacteria,2Q9B3@267890|Shewanellaceae	1236|Gammaproteobacteria	V	PFAM secretion protein HlyD family protein	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
k141_6463_1	1469613.JT55_09940	9.51e-66	223.0	COG5009@1|root,COG5009@2|Bacteria,1MU5A@1224|Proteobacteria,2USBB@28211|Alphaproteobacteria,3FCG1@34008|Rhodovulum	28211|Alphaproteobacteria	M	Transglycosylase	mrcA	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	PCB_OB,Transgly,Transpeptidase
k141_9539_1	1123237.Salmuc_04101	6.51e-94	299.0	COG2844@1|root,COG2844@2|Bacteria,1MV54@1224|Proteobacteria,2TSV0@28211|Alphaproteobacteria	28211|Alphaproteobacteria	O	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen	glnD	GO:0006355,GO:0006464,GO:0006807,GO:0006808,GO:0007154,GO:0007584,GO:0008150,GO:0008152,GO:0009605,GO:0009719,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0009991,GO:0010033,GO:0010243,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0018175,GO:0018177,GO:0019219,GO:0019222,GO:0019538,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031667,GO:0031668,GO:0031669,GO:0031670,GO:0036211,GO:0042221,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0070887,GO:0071310,GO:0071417,GO:0071495,GO:0071496,GO:0071704,GO:0080090,GO:0090293,GO:1901564,GO:1901698,GO:1901699,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141	2.7.7.59	ko:K00990	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	-	-	-	ACT,GlnD_UR_UTase,GlnE,HD,NTP_transf_2
k141_1525_1	272952.HpaP802650	2.17e-05	52.4	2CMKC@1|root,2QQNW@2759|Eukaryota,3Q9GY@4776|Peronosporales	4776|Peronosporales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_8881_1	1242864.D187_003418	8.25e-51	174.0	COG1219@1|root,COG1219@2|Bacteria,1MVQK@1224|Proteobacteria,42MWJ@68525|delta/epsilon subdivisions,2WJ8Q@28221|Deltaproteobacteria,2YUHC@29|Myxococcales	28221|Deltaproteobacteria	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
k141_5840_1	1121422.AUMW01000012_gene2993	6.48e-117	351.0	COG0008@1|root,COG0008@2|Bacteria,1TP8G@1239|Firmicutes,247Y0@186801|Clostridia,2607A@186807|Peptococcaceae	186801|Clostridia	J	PFAM tRNA synthetases class I (E and Q), catalytic domain	glnS	-	6.1.1.18	ko:K01886	ko00970,ko01100,map00970,map01100	M00359,M00360	R03652	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1c,tRNA-synt_1c_C
k141_1526_1	234831.PSM_A1720	0.000921	44.3	COG0628@1|root,COG0628@2|Bacteria,1MXXU@1224|Proteobacteria,1RQCM@1236|Gammaproteobacteria,2PZTM@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	S	AI-2E family transporter	tqsA	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0009372,GO:0009987,GO:0015562,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0044764,GO:0051179,GO:0051234,GO:0051704,GO:0055085,GO:0071944	-	ko:K11744	-	-	-	-	ko00000	-	-	-	AI-2E_transport
k141_1526_2	235909.GK1635	1.12e-11	63.5	COG1225@1|root,COG1225@2|Bacteria,1V058@1239|Firmicutes,4HE2H@91061|Bacilli,1WF9R@129337|Geobacillus	91061|Bacilli	O	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
k141_7641_2	426114.THI_0379	9.93e-09	55.8	COG0266@1|root,COG0266@2|Bacteria,1MVM5@1224|Proteobacteria,2VI10@28216|Betaproteobacteria,1KJ6R@119065|unclassified Burkholderiales	28216|Betaproteobacteria	L	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates	fpg	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
k141_9541_1	398580.Dshi_2290	3.47e-25	105.0	COG3659@1|root,COG3659@2|Bacteria,1R8TI@1224|Proteobacteria,2URIQ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	Carbohydrate-selective porin, OprB family	-	-	-	ko:K07267	-	-	-	-	ko00000,ko02000	1.B.19.1	-	-	OprB
k141_4615_1	985867.AEWF01000002_gene1663	1.34e-81	258.0	COG0459@1|root,COG0459@2|Bacteria,1MURR@1224|Proteobacteria,2TS07@28211|Alphaproteobacteria,47EV8@766|Rickettsiales	766|Rickettsiales	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groEL	-	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
k141_357_2	1229909.NSED_07810	5.94e-44	142.0	arCOG08687@1|root,arCOG08687@2157|Archaea,41SVF@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_5291_1	1260251.SPISAL_04590	3.91e-05	44.3	COG0691@1|root,COG0691@2|Bacteria,1RDFP@1224|Proteobacteria,1S3PT@1236|Gammaproteobacteria,1WX50@135613|Chromatiales	135613|Chromatiales	O	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA	smpB	-	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
k141_9588_1	35128.Thapsdraft2050	2.12e-64	223.0	COG0086@1|root,2RUNH@2759|Eukaryota,2XF5V@2836|Bacillariophyta	2836|Bacillariophyta	H	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC2	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009536,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464	-	-	-	-	-	-	-	-	-	-	RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
k141_2820_1	388467.A19Y_0423	4.93e-36	125.0	COG0185@1|root,COG0185@2|Bacteria,1G6J7@1117|Cyanobacteria,1HBJE@1150|Oscillatoriales	1117|Cyanobacteria	J	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA	rpsS	GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904	-	ko:K02965	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S19
k141_358_1	2340.JV46_19520	1.8e-99	296.0	COG1213@1|root,COG1213@2|Bacteria,1RB54@1224|Proteobacteria,1SFWW@1236|Gammaproteobacteria,1JBGH@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	MobA-like NTP transferase domain	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_3,NTP_transferase
k141_5292_1	1120953.AUBH01000002_gene1393	1.35e-56	196.0	COG1199@1|root,COG1199@2|Bacteria,1MVCU@1224|Proteobacteria,1RMNX@1236|Gammaproteobacteria,465XA@72275|Alteromonadaceae	1236|Gammaproteobacteria	KL	COG1199 Rad3-related DNA helicases	yoaA	GO:0003674,GO:0003824,GO:0004386,GO:0006139,GO:0006259,GO:0006281,GO:0006301,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008026,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0070035,GO:0071704,GO:0090304,GO:1901360	3.6.4.12	ko:K03722	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DEAD_2,Helicase_C_2,ResIII
k141_8936_1	32042.PstZobell_18625	2.75e-59	193.0	COG3039@1|root,COG3039@2|Bacteria,1MUVI@1224|Proteobacteria,1RQVT@1236|Gammaproteobacteria,1Z1TJ@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	L	COG3666 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_6,DUF772
k141_2821_1	314225.ELI_02500	3.49e-32	128.0	COG1020@1|root,COG1020@2|Bacteria,1N7HY@1224|Proteobacteria,2TRZV@28211|Alphaproteobacteria,2K46G@204457|Sphingomonadales	204457|Sphingomonadales	Q	Protein of unknown function (DUF1298)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1298,WES_acyltransf
k141_359_1	1118235.CAJH01000028_gene2004	9.39e-62	210.0	COG0178@1|root,COG0178@2|Bacteria,1MW0W@1224|Proteobacteria,1RMS9@1236|Gammaproteobacteria,1X45Q@135614|Xanthomonadales	135614|Xanthomonadales	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
k141_359_2	396588.Tgr7_2294	5.58e-10	59.3	COG0477@1|root,COG2814@2|Bacteria,1MVSH@1224|Proteobacteria,1RN70@1236|Gammaproteobacteria,1WXE2@135613|Chromatiales	135613|Chromatiales	EGP	PFAM Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
k141_5906_1	1280948.HY36_17900	1.09e-130	378.0	COG2801@1|root,COG2801@2|Bacteria,1MVN5@1224|Proteobacteria,2TQK0@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	COG2801 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	HTH_21,rve,rve_3
k141_3420_1	177437.HRM2_32430	3.46e-14	76.3	COG2009@1|root,2ZBTX@2|Bacteria,1RB22@1224|Proteobacteria,42NAY@68525|delta/epsilon subdivisions,2WMPM@28221|Deltaproteobacteria,2MJ7Q@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Succinate dehydrogenase/Fumarate reductase transmembrane subunit	-	-	-	ko:K00246	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	M00009,M00011,M00150,M00173	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	Sdh_cyt
k141_5293_1	254945.Erum4790	7.17e-24	94.7	COG0713@1|root,COG0713@2|Bacteria,1RH0S@1224|Proteobacteria,2U93P@28211|Alphaproteobacteria,47FFJ@766|Rickettsiales	766|Rickettsiales	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoK	-	1.6.5.3	ko:K00340	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q2
k141_974_1	384765.SIAM614_24162	7.48e-39	144.0	COG4664@1|root,COG4664@2|Bacteria,1R4MZ@1224|Proteobacteria,2TQNR@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	TRAP-type mannitol chloroaromatic compound transport system large permease component	-	-	-	-	-	-	-	-	-	-	-	-	DctM
k141_974_2	909943.HIMB100_00012010	1.06e-34	129.0	COG4665@1|root,COG4665@2|Bacteria,1R4T4@1224|Proteobacteria,2U2FK@28211|Alphaproteobacteria,4BREP@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	Q	TRAP-type mannitol chloroaromatic compound transport system, small permease component	-	-	-	-	-	-	-	-	-	-	-	-	DctQ
k141_6527_1	1089552.KI911559_gene550	5.73e-69	213.0	COG0066@1|root,COG0066@2|Bacteria,1MVXB@1224|Proteobacteria,2TRRS@28211|Alphaproteobacteria,2JPTP@204441|Rhodospirillales	204441|Rhodospirillales	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuD	-	4.2.1.33,4.2.1.35	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R10170	RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase_C
k141_6527_2	1267533.KB906733_gene3344	1.98e-08	54.7	COG0065@1|root,COG0065@2|Bacteria,3Y2ID@57723|Acidobacteria,2JI0J@204432|Acidobacteriia	204432|Acidobacteriia	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuC	-	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase
k141_3421_1	870187.Thini_4125	2.29e-50	169.0	COG2010@1|root,COG2010@2|Bacteria,1MUCW@1224|Proteobacteria,1RPYJ@1236|Gammaproteobacteria,4611A@72273|Thiotrichales	72273|Thiotrichales	C	C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex	-	-	-	ko:K00406	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	Cytochrome_CBB3,FixP_N
k141_7707_1	675812.VHA_003037	1.2e-29	117.0	COG0564@1|root,COG0564@2|Bacteria,1MVDX@1224|Proteobacteria,1RPAN@1236|Gammaproteobacteria,1XT4V@135623|Vibrionales	135623|Vibrionales	J	Responsible for synthesis of pseudouridine from uracil	rluC	GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	5.4.99.24	ko:K06179	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
k141_7707_2	351016.RAZWK3B_03875	3.45e-06	51.2	COG0546@1|root,COG0546@2|Bacteria,1RDA7@1224|Proteobacteria,2U703@28211|Alphaproteobacteria,2P2RN@2433|Roseobacter	28211|Alphaproteobacteria	S	HAD-superfamily hydrolase, subfamily IA, variant 1	ppaX	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
k141_2215_1	391593.RCCS2_11307	9.08e-101	296.0	COG0092@1|root,COG0092@2|Bacteria,1MUAI@1224|Proteobacteria,2TRZ2@28211|Alphaproteobacteria,2P2HT@2433|Roseobacter	28211|Alphaproteobacteria	J	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation	rpsC	GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02982	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KH_2,Ribosomal_S3_C
k141_2215_2	314271.RB2654_11153	7.12e-27	100.0	COG0197@1|root,COG0197@2|Bacteria,1RA0Z@1224|Proteobacteria,2U710@28211|Alphaproteobacteria	28211|Alphaproteobacteria	J	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs	rplP	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904	-	ko:K02878	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L16
k141_975_1	1449076.JOOE01000001_gene2747	2.52e-37	143.0	COG0577@1|root,COG0577@2|Bacteria,1NREW@1224|Proteobacteria,2U1KH@28211|Alphaproteobacteria,2K128@204457|Sphingomonadales	204457|Sphingomonadales	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
k141_7211_2	1229909.NSED_06505	7.72e-139	400.0	COG0045@1|root,arCOG01337@2157|Archaea,41S5M@651137|Thaumarchaeota	651137|Thaumarchaeota	C	ATP-grasp domain	-	-	6.2.1.5	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,Ligase_CoA
k141_5371_1	1049564.TevJSym_al00200	7.66e-99	303.0	COG0493@1|root,COG0493@2|Bacteria,1MU2H@1224|Proteobacteria,1RREP@1236|Gammaproteobacteria,1J5XD@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_20,Fer4_7,NADH_4Fe-4S,Pyr_redox_2,Pyr_redox_3
k141_8412_1	1336235.JAEG01000001_gene2162	1.85e-141	410.0	COG0015@1|root,COG0015@2|Bacteria,1MV4B@1224|Proteobacteria,2TQUE@28211|Alphaproteobacteria,4BA9J@82115|Rhizobiaceae	28211|Alphaproteobacteria	F	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	purB	GO:0003674,GO:0003824,GO:0004018,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016840,GO:0016842,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046033,GO:0046390,GO:0046483,GO:0055086,GO:0070626,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ADSL_C,Lyase_1
k141_4135_1	1229909.NSED_01170	1.39e-17	78.6	COG1413@1|root,arCOG02966@2157|Archaea,41T3Y@651137|Thaumarchaeota	651137|Thaumarchaeota	C	HEAT repeats	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_4135_2	1229909.NSED_01165	3.39e-63	199.0	COG1018@1|root,arCOG02200@2157|Archaea,41S72@651137|Thaumarchaeota	651137|Thaumarchaeota	C	oxidoreductase FAD NAD(P)-binding	-	-	1.18.1.2,1.19.1.1	ko:K00528	-	-	R10159	-	ko00000,ko01000	-	-	-	FAD_binding_6,NAD_binding_1
k141_433_1	1380384.JADN01000007_gene1684	1.06e-28	115.0	COG0308@1|root,COG0308@2|Bacteria,4NE13@976|Bacteroidetes,1HWXD@117743|Flavobacteriia	976|Bacteroidetes	E	aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
k141_433_2	1250006.JHZZ01000001_gene3081	3.82e-18	79.0	2AE6H@1|root,3140B@2|Bacteria,4NSDV@976|Bacteroidetes,1I2EY@117743|Flavobacteriia,3VWI0@52959|Polaribacter	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_7212_1	631362.Thi970DRAFT_03477	1.06e-92	290.0	COG0445@1|root,COG0445@2|Bacteria,1MU6F@1224|Proteobacteria,1RMM1@1236|Gammaproteobacteria,1WXBH@135613|Chromatiales	135613|Chromatiales	D	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34	gidA	-	-	ko:K03495	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko03016,ko03036	-	-	-	GIDA,GIDA_assoc
k141_5372_1	1163409.UUA_08346	4.62e-51	182.0	COG0823@1|root,COG0823@2|Bacteria,1MWYK@1224|Proteobacteria,1RXYW@1236|Gammaproteobacteria,1XD03@135614|Xanthomonadales	135614|Xanthomonadales	U	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	PD40
k141_9003_1	1254432.SCE1572_04135	6.8e-50	172.0	COG2513@1|root,COG2513@2|Bacteria,1N4VT@1224|Proteobacteria,42NZ1@68525|delta/epsilon subdivisions,2WNX5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate	prpB	-	4.1.3.30	ko:K03417	ko00640,map00640	-	R00409	RC00286,RC00287	ko00000,ko00001,ko01000	-	-	-	PEP_mutase
k141_4754_1	583355.Caka_2254	5.48e-46	166.0	COG0573@1|root,COG0573@2|Bacteria,46T46@74201|Verrucomicrobia,3K7GY@414999|Opitutae	414999|Opitutae	P	probably responsible for the translocation of the substrate across the membrane	-	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
k141_6600_1	1167006.UWK_00327	6.62e-117	348.0	COG0004@1|root,COG0004@2|Bacteria,1NR9F@1224|Proteobacteria,42M8M@68525|delta/epsilon subdivisions,2WJE2@28221|Deltaproteobacteria,2MISS@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Ammonium Transporter	-	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
k141_4136_1	111781.Lepto7376_1881	4.86e-13	69.3	2B3PJ@1|root,31WD1@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_4136_2	754035.Mesau_04872	3.33e-08	54.3	COG1595@1|root,COG1595@2|Bacteria,1MZMC@1224|Proteobacteria,2U4IC@28211|Alphaproteobacteria,43KZK@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
k141_4755_1	1380600.AUYN01000009_gene2056	3.66e-102	322.0	COG0542@1|root,COG0542@2|Bacteria,4NE1J@976|Bacteroidetes,1HWVR@117743|Flavobacteriia	976|Bacteroidetes	O	Belongs to the ClpA ClpB family	clpC	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
k141_3482_1	631362.Thi970DRAFT_04762	1.81e-143	417.0	COG0330@1|root,COG0330@2|Bacteria,1MUM2@1224|Proteobacteria,1RMUG@1236|Gammaproteobacteria,1WWWJ@135613|Chromatiales	135613|Chromatiales	O	HflC and HflK could encode or regulate a protease	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
k141_9664_1	870187.Thini_2989	1.63e-104	320.0	COG1217@1|root,COG1217@2|Bacteria,1MV5Q@1224|Proteobacteria,1RMJB@1236|Gammaproteobacteria,45ZNP@72273|Thiotrichales	72273|Thiotrichales	T	GTP-binding protein TypA	-	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2
k141_2289_1	396588.Tgr7_0038	2.72e-70	226.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria,1X04M@135613|Chromatiales	135613|Chromatiales	T	Sigma-54 interaction domain	-	-	-	ko:K07713	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
k141_8416_1	1484460.JSWG01000015_gene1232	1.02e-85	280.0	COG0308@1|root,COG0842@1|root,COG0308@2|Bacteria,COG0842@2|Bacteria,4NF3R@976|Bacteroidetes,1HXJJ@117743|Flavobacteriia	976|Bacteroidetes	E	Peptidase family M1 domain	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC2_membrane_4,ABC2_membrane_5,Peptidase_M1
k141_2903_1	143224.JQMD01000002_gene2628	2.31e-73	233.0	COG1257@1|root,COG1257@2|Bacteria,4NGNG@976|Bacteroidetes,1HY0M@117743|Flavobacteriia	976|Bacteroidetes	I	Belongs to the HMG-CoA reductase family	mvaA	-	1.1.1.88	ko:K00054	ko00900,ko01110,ko01130,map00900,map01110,map01130	-	R02081	RC00004,RC00644	ko00000,ko00001,ko01000	-	-	-	HMG-CoA_red
k141_1049_1	648757.Rvan_2927	1.44e-87	273.0	COG3278@1|root,COG3278@2|Bacteria,1MU18@1224|Proteobacteria,2TR2C@28211|Alphaproteobacteria,3N7QH@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	C	Belongs to the heme-copper respiratory oxidase family	ccoN	GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015672,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0022900,GO:0022904,GO:0034220,GO:0044237,GO:0044464,GO:0045333,GO:0051179,GO:0051234,GO:0055085,GO:0055114,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:1902600	1.9.3.1	ko:K00404	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	COX1
k141_4138_1	159749.E7BWK8	5.88e-104	328.0	COG0542@1|root,KOG1051@2759|Eukaryota,2XEW9@2836|Bacillariophyta	2836|Bacillariophyta	O	Belongs to the ClpA ClpB family	-	-	-	-	-	-	-	-	-	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
k141_7216_1	1379698.RBG1_1C00001G0054	2.48e-100	301.0	COG2502@1|root,COG2502@2|Bacteria,2NNKP@2323|unclassified Bacteria	2|Bacteria	E	Aspartate-ammonia ligase	asnA	GO:0003674,GO:0003824,GO:0004071,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006528,GO:0006529,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009987,GO:0016053,GO:0016211,GO:0016874,GO:0016879,GO:0016880,GO:0019752,GO:0032787,GO:0033554,GO:0034641,GO:0042802,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050896,GO:0051716,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	6.3.1.1	ko:K01914	ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230	-	R00483	RC00010	ko00000,ko00001,ko01000	-	-	iAPECO1_1312.APECO1_2719,iECOK1_1307.ECOK1_4193,iECS88_1305.ECS88_4166,iUMN146_1321.UM146_18910,iUTI89_1310.UTI89_C4299	AsnA
k141_1050_1	1444770.AF72_12610	1.07e-21	95.1	28JKJ@1|root,2Z9DD@2|Bacteria,1MUN2@1224|Proteobacteria	1224|Proteobacteria	S	Phage P22-like portal protein	-	-	-	-	-	-	-	-	-	-	-	-	P22_portal
k141_6604_2	1449351.RISW2_01670	1.9e-64	204.0	COG0508@1|root,COG0508@2|Bacteria,1MU7K@1224|Proteobacteria,2TS31@28211|Alphaproteobacteria,4KN8A@93682|Roseivivax	28211|Alphaproteobacteria	C	2-oxoacid dehydrogenases acyltransferase (catalytic domain)	-	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,E3_binding
k141_5973_1	491952.Mar181_0298	5.62e-84	276.0	COG0458@1|root,COG0458@2|Bacteria,1MUDZ@1224|Proteobacteria,1RPIU@1236|Gammaproteobacteria,1XHKH@135619|Oceanospirillales	135619|Oceanospirillales	F	Carbamoyl-phosphate synthetase ammonia chain	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
k141_3484_1	488538.SAR116_0950	5.16e-96	288.0	COG1173@1|root,COG1173@2|Bacteria,1MUG0@1224|Proteobacteria,2TT4V@28211|Alphaproteobacteria,4BPQN@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	EP	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
k141_1675_2	1147.D082_18590	3.13e-09	52.8	2EHNG@1|root,33BE9@2|Bacteria,1GAFH@1117|Cyanobacteria,1H602@1142|Synechocystis	1117|Cyanobacteria	U	Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions. PetG is required for either the stability or assembly of the cytochrome b6-f complex	petG	-	-	ko:K02640	ko00195,ko01100,map00195,map01100	M00162	-	-	ko00000,ko00001,ko00002,ko00194	-	-	-	PetG
k141_6605_1	196367.JNFG01000026_gene8234	9.96e-19	90.5	COG4166@1|root,COG4166@2|Bacteria,1P91R@1224|Proteobacteria,2VMKG@28216|Betaproteobacteria,1KGI3@119060|Burkholderiaceae	28216|Betaproteobacteria	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	SBP_bac_5
k141_5378_2	765912.Thimo_2222	5.29e-37	132.0	COG0231@1|root,COG0231@2|Bacteria,1MW2J@1224|Proteobacteria,1RPW7@1236|Gammaproteobacteria,1WX8C@135613|Chromatiales	135613|Chromatiales	J	Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-34 is required for alleviation	efp	-	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
k141_2905_1	649747.HMPREF0083_04612	5.64e-10	68.2	COG3547@1|root,COG3547@2|Bacteria,1TP4A@1239|Firmicutes,4HDAB@91061|Bacilli,26R4G@186822|Paenibacillaceae	91061|Bacilli	L	Transposase, IS116	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k141_4759_1	1121033.AUCF01000020_gene662	2.24e-122	365.0	COG0459@1|root,COG0459@2|Bacteria,1MURR@1224|Proteobacteria,2TS07@28211|Alphaproteobacteria,2JPIQ@204441|Rhodospirillales	204441|Rhodospirillales	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	-	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
k141_4141_1	1240350.AMZE01000007_gene2783	7.72e-55	181.0	COG1121@1|root,COG1121@2|Bacteria,1MUDW@1224|Proteobacteria,1RPJT@1236|Gammaproteobacteria,1YXED@136845|Pseudomonas putida group	1236|Gammaproteobacteria	P	Part of the ABC transporter complex ZnuABC involved in zinc import. Responsible for energy coupling to the transport system	znuC	GO:0000041,GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005385,GO:0005488,GO:0005524,GO:0006810,GO:0006811,GO:0006812,GO:0006829,GO:0008144,GO:0008150,GO:0008324,GO:0015075,GO:0015318,GO:0015399,GO:0015405,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022890,GO:0030001,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0043167,GO:0043168,GO:0043492,GO:0046873,GO:0046915,GO:0051179,GO:0051234,GO:0055085,GO:0070838,GO:0071577,GO:0072509,GO:0072511,GO:0097159,GO:0097367,GO:0098655,GO:0098660,GO:0098662,GO:1901265,GO:1901363	-	ko:K09817	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.15.3,3.A.1.15.5	-	iSFV_1184.SFV_1859,iSF_1195.SF1867,iSFxv_1172.SFxv_2092,iS_1188.S1934	ABC_tran
k141_6606_1	1123392.AQWL01000011_gene2257	1.72e-128	374.0	COG0517@1|root,COG0517@2|Bacteria,1MXI6@1224|Proteobacteria,2VJ2W@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	Y2_Tnp,Zn_Tnp_IS91
k141_441_1	1121875.KB907558_gene545	9.69e-100	298.0	2CC76@1|root,3435K@2|Bacteria,4P48D@976|Bacteroidetes,1I9GK@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_4760_1	1185766.DL1_09885	1.76e-54	182.0	COG0216@1|root,COG0216@2|Bacteria,1MV28@1224|Proteobacteria,2TQSV@28211|Alphaproteobacteria,2XMF1@285107|Thioclava	28211|Alphaproteobacteria	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
k141_7784_1	159749.K0T6C5	2.58e-226	684.0	COG2801@1|root,KOG0017@2759|Eukaryota,2XF4I@2836|Bacillariophyta	159749.K0T6C5|-	L	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_5976_1	314264.ROS217_16475	3.08e-46	159.0	COG0683@1|root,COG0683@2|Bacteria,1MV3Y@1224|Proteobacteria,2TU2B@28211|Alphaproteobacteria,46NXM@74030|Roseovarius	28211|Alphaproteobacteria	E	COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component	-	-	-	ko:K01999,ko:K11959	ko02010,ko02024,map02010,map02024	M00237,M00323	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4,3.A.1.4.4,3.A.1.4.5	-	-	Peripla_BP_6,TAT_signal
k141_5976_2	1288298.rosmuc_01021	2.75e-28	107.0	COG1028@1|root,COG1028@2|Bacteria,1MW50@1224|Proteobacteria,2TSYP@28211|Alphaproteobacteria,46NS8@74030|Roseovarius	28211|Alphaproteobacteria	IQ	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	benD	-	1.3.1.25	ko:K05783	ko00362,ko00364,ko00622,ko01100,ko01120,ko01220,map00362,map00364,map00622,map01100,map01120,map01220	M00551	R00813,R05292,R05293,R05309,R05314,R08111,R08112,R08113	RC00271,RC01326,RC01327	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	adh_short,adh_short_C2
k141_3486_1	1123392.AQWL01000008_gene1146	3.02e-49	180.0	COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,2VHCZ@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K07239	-	-	-	-	ko00000	2.A.6.1	-	-	ACR_tran
k141_4331_1	1121271.AUCM01000007_gene3789	6.02e-08	53.1	COG1028@1|root,COG1028@2|Bacteria,1Q3GM@1224|Proteobacteria,2U25Q@28211|Alphaproteobacteria	28211|Alphaproteobacteria	IQ	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
k141_4331_2	1366046.HIMB11_00494	2.33e-58	187.0	COG1083@1|root,COG1083@2|Bacteria,1QACI@1224|Proteobacteria,2UDFZ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	COG1083 CMP-N-acetylneuraminic acid synthetase	ptmB	-	2.7.7.43	ko:K00983	ko00520,ko01100,map00520,map01100	-	R01117,R04215	RC00152	ko00000,ko00001,ko01000	-	-	-	CTP_transf_3
k141_12_1	313598.MED152_08180	4.73e-63	206.0	COG0469@1|root,COG0469@2|Bacteria,4NEEU@976|Bacteroidetes,1HX84@117743|Flavobacteriia,3VW8V@52959|Polaribacter	976|Bacteroidetes	G	Pyruvate kinase, barrel domain	pyk	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PK,PK_C
k141_3098_1	1125863.JAFN01000001_gene2693	2.45e-62	211.0	COG0443@1|root,COG0443@2|Bacteria,1MVEN@1224|Proteobacteria,42M64@68525|delta/epsilon subdivisions,2WIWS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
k141_6799_1	1121935.AQXX01000136_gene4084	1.05e-90	278.0	COG0621@1|root,COG0621@2|Bacteria,1MU7N@1224|Proteobacteria,1RN46@1236|Gammaproteobacteria,1XI9G@135619|Oceanospirillales	135619|Oceanospirillales	H	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12	rimO	-	2.8.4.4	ko:K14441	-	-	R10652	RC00003,RC03217	ko00000,ko01000,ko03009	-	-	-	Radical_SAM,UPF0004
k141_5566_1	1316936.K678_10936	6.61e-107	337.0	COG0060@1|root,COG0060@2|Bacteria,1MVBQ@1224|Proteobacteria,2TR3N@28211|Alphaproteobacteria,2JPW3@204441|Rhodospirillales	204441|Rhodospirillales	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1,zf-FPG_IleRS
k141_7411_1	1049564.TevJSym_ak00590	2.43e-100	308.0	COG0018@1|root,COG0018@2|Bacteria,1MU4J@1224|Proteobacteria,1RPRC@1236|Gammaproteobacteria,1J5IS@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	Arginyl-tRNA synthetase	argS	GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
k141_4332_1	1220582.RRU01S_25_00140	4.58e-92	283.0	COG0446@1|root,COG0446@2|Bacteria,1NR3M@1224|Proteobacteria,2TS0K@28211|Alphaproteobacteria,4B77F@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	oxidoreductase	thcD	-	1.14.13.111,1.18.1.3	ko:K00529,ko:K16968	ko00071,ko00360,ko00920,ko01120,ko01220,map00071,map00360,map00920,map01120,map01220	M00545	R02000,R06782,R06783,R09513	RC00098,RC02556	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	Pyr_redox_2,Reductase_C
k141_3099_1	1288826.MSNKSG1_09578	4.83e-63	207.0	COG0477@1|root,COG2814@2|Bacteria,1N2NP@1224|Proteobacteria,1RP1Y@1236|Gammaproteobacteria,4664N@72275|Alteromonadaceae	1236|Gammaproteobacteria	EGP	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
k141_2484_1	1229909.NSED_08705	4.6e-175	498.0	COG1012@1|root,arCOG01252@2157|Archaea,41T0F@651137|Thaumarchaeota	651137|Thaumarchaeota	C	PFAM Aldehyde dehydrogenase	-	-	1.2.1.16,1.2.1.20,1.2.1.79	ko:K00135,ko:K18601	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	M00027	R00713,R00714,R02401	RC00080	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
k141_14_1	1453496.AT03_15335	5.51e-70	228.0	COG1061@1|root,COG1061@2|Bacteria,1MV9F@1224|Proteobacteria,1RR0U@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	helicase	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,ResIII
k141_1249_2	35128.Thapsdraft1258	5.75e-61	187.0	COG0633@1|root,2S3RJ@2759|Eukaryota,2XGJF@2836|Bacillariophyta	2836|Bacillariophyta	C	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions	-	-	-	ko:K02639	ko00195,map00195	-	-	-	ko00000,ko00001,ko00194	-	-	-	Fer2
k141_1249_3	159749.E7BWJ0	4.9e-05	43.5	COG0335@1|root,KOG1698@2759|Eukaryota,2XFXY@2836|Bacillariophyta	2836|Bacillariophyta	J	Ribosomal protein L19	-	GO:0000313,GO:0000315,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005761,GO:0005762,GO:0005840,GO:0009507,GO:0009536,GO:0015934,GO:0031974,GO:0032991,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044391,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0070013,GO:0098798,GO:1990904	-	-	-	-	-	-	-	-	-	-	Ribosomal_L19
k141_8025_1	10224.XP_006826129.1	2.64e-67	239.0	COG2801@1|root,KOG0017@2759|Eukaryota,38F42@33154|Opisthokonta,3BA5H@33208|Metazoa,3CWAK@33213|Bilateria	33208|Metazoa	E	K02A2.6-like	-	-	-	-	-	-	-	-	-	-	-	-	RVT_1,SCAN,rve,zf-CCHC,zf-H2C2
k141_6801_1	1085623.GNIT_2782	2.13e-92	300.0	COG0591@1|root,COG3437@1|root,COG4251@1|root,COG0591@2|Bacteria,COG3437@2|Bacteria,COG4251@2|Bacteria,1QTSW@1224|Proteobacteria,1T1G2@1236|Gammaproteobacteria,46D5M@72275|Alteromonadaceae	1236|Gammaproteobacteria	T	PAS fold	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4,PAS_7,Response_reg,SSF
k141_8643_2	1396141.BATP01000057_gene3058	6.82e-18	82.8	2CK46@1|root,337US@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Gcw_chp
k141_632_1	1229909.NSED_02600	5.74e-75	232.0	COG1405@1|root,arCOG01981@2157|Archaea,41S8Y@651137|Thaumarchaeota	651137|Thaumarchaeota	K	factor TFIIB	-	-	-	ko:K03124	ko03022,ko05169,ko05203,map03022,map05169,map05203	-	-	-	ko00000,ko00001,ko03021	-	-	-	TFIIB,TF_Zn_Ribbon
k141_632_2	1229909.NSED_02595	1.91e-31	117.0	COG0396@1|root,arCOG04236@2157|Archaea,41SE1@651137|Thaumarchaeota	651137|Thaumarchaeota	O	FeS assembly ATPase SufC	-	-	-	ko:K09013	-	-	-	-	ko00000,ko02000	-	-	-	ABC_tran
k141_7413_1	864051.BurJ1DRAFT_4689	2.72e-57	201.0	COG2132@1|root,COG2132@2|Bacteria,1N9H3@1224|Proteobacteria,2VZQA@28216|Betaproteobacteria,1KNDH@119065|unclassified Burkholderiales	28216|Betaproteobacteria	Q	Multicopper oxidase	-	-	1.16.3.3	ko:K22349	-	-	-	-	ko00000,ko01000	-	-	-	-
k141_9266_2	1097668.BYI23_C011920	7.47e-28	109.0	COG2826@1|root,COG2826@2|Bacteria,1PP49@1224|Proteobacteria,2VI0E@28216|Betaproteobacteria,1K4KX@119060|Burkholderiaceae	28216|Betaproteobacteria	L	PFAM Integrase catalytic	-	-	-	-	-	-	-	-	-	-	-	-	HTH_38,rve
k141_3102_1	1380600.AUYN01000009_gene1794	5.9e-90	266.0	COG0461@1|root,COG0461@2|Bacteria,4NEF8@976|Bacteroidetes,1HXXU@117743|Flavobacteriia	976|Bacteroidetes	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	pyrE	-	2.4.2.10,4.1.1.23	ko:K00762,ko:K13421	ko00240,ko00983,ko01100,map00240,map00983,map01100	M00051	R00965,R01870,R08231	RC00063,RC00409,RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase,Pribosyltran
k141_6184_2	626887.J057_19445	9.2e-05	43.9	COG0564@1|root,COG0564@2|Bacteria,1MVDX@1224|Proteobacteria,1RPAN@1236|Gammaproteobacteria,464VS@72275|Alteromonadaceae	1236|Gammaproteobacteria	J	Responsible for synthesis of pseudouridine from uracil	rluC	GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	5.4.99.24	ko:K06179	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
k141_633_1	1123256.KB907939_gene299	3.79e-23	98.2	COG1999@1|root,COG1999@2|Bacteria,1N6R6@1224|Proteobacteria,1SC88@1236|Gammaproteobacteria,1X800@135614|Xanthomonadales	135614|Xanthomonadales	S	signal sequence binding	-	-	-	-	-	-	-	-	-	-	-	-	SCO1-SenC
k141_1868_1	768671.ThimaDRAFT_0313	1.83e-26	105.0	COG0647@1|root,COG0647@2|Bacteria,1QGX4@1224|Proteobacteria,1RRS1@1236|Gammaproteobacteria,1WW2T@135613|Chromatiales	135613|Chromatiales	G	TIGRFAM HAD-superfamily subfamily IIA hydrolase like protein	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_6,Hydrolase_like
k141_1868_2	1005994.GTGU_01636	7.3e-11	62.0	COG0516@1|root,COG0516@2|Bacteria,1MUJM@1224|Proteobacteria,1RPZY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	F	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides	guaC	GO:0003674,GO:0003824,GO:0003920,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0015949,GO:0015950,GO:0015951,GO:0016491,GO:0016651,GO:0016657,GO:0019637,GO:0019693,GO:0034641,GO:0042802,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564	1.1.1.205,1.7.1.7	ko:K00088,ko:K00364	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R01134,R08240	RC00143,RC00457,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iEC042_1314.EC042_0103,iECIAI39_1322.ECIAI39_0105,iECUMN_1333.ECUMN_0102	IMPDH
k141_18_1	1469613.JT55_01980	1.5e-101	309.0	COG0539@1|root,COG0539@2|Bacteria,1MVAV@1224|Proteobacteria,2TQPV@28211|Alphaproteobacteria,3FCS0@34008|Rhodovulum	28211|Alphaproteobacteria	J	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence	rpsA	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
k141_4954_1	159749.E7BWD8	5.71e-212	593.0	COG0055@1|root,KOG1350@2759|Eukaryota,2XE2T@2836|Bacillariophyta	2836|Bacillariophyta	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpB	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
k141_6804_2	387092.NIS_0230	4.08e-17	77.0	COG0197@1|root,COG0197@2|Bacteria,1RA0Z@1224|Proteobacteria,42QW5@68525|delta/epsilon subdivisions,2YNWG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs	rplP	-	-	ko:K02878	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L16
k141_1869_1	1208323.B30_05302	5.04e-35	130.0	COG0705@1|root,COG0705@2|Bacteria,1MYFP@1224|Proteobacteria,2TSJG@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	membrane protein (homolog of Drosophila rhomboid)	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
k141_1869_2	1122614.JHZF01000013_gene3799	1.51e-08	55.1	COG1594@1|root,COG1594@2|Bacteria,1MWK8@1224|Proteobacteria,2U0YM@28211|Alphaproteobacteria,2PCFP@252301|Oceanicola	28211|Alphaproteobacteria	K	COG1198 Primosomal protein N' (replication factor Y) - superfamily II helicase	-	-	-	-	-	-	-	-	-	-	-	-	zf-RRN7
k141_5569_1	99598.Cal7507_2933	4.95e-31	112.0	COG0051@1|root,COG0051@2|Bacteria,1G5TJ@1117|Cyanobacteria,1HNE4@1161|Nostocales	1117|Cyanobacteria	J	Involved in the binding of tRNA to the ribosomes	rpsJ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02946	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S10
k141_5569_2	159749.E7BWP5	1.06e-248	686.0	COG0050@1|root,KOG0460@2759|Eukaryota,2XBKK@2836|Bacillariophyta	2759|Eukaryota	J	Elongation factor Tu	tufA	GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005634,GO:0005730,GO:0005737,GO:0009295,GO:0009507,GO:0009526,GO:0009532,GO:0009534,GO:0009535,GO:0009536,GO:0009570,GO:0009579,GO:0009941,GO:0016020,GO:0020011,GO:0031967,GO:0031974,GO:0031975,GO:0031976,GO:0031981,GO:0031984,GO:0034357,GO:0042651,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044422,GO:0044424,GO:0044428,GO:0044434,GO:0044435,GO:0044436,GO:0044444,GO:0044446,GO:0044464,GO:0048046,GO:0055035,GO:0070013	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
k141_6186_1	391593.RCCS2_04319	2.79e-136	417.0	COG0587@1|root,COG0587@2|Bacteria,1MUE4@1224|Proteobacteria,2TRUB@28211|Alphaproteobacteria,2P2AF@2433|Roseobacter	28211|Alphaproteobacteria	L	DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase	dnaE2	GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496	2.7.7.7	ko:K02337,ko:K14162	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
k141_1254_1	991905.SL003B_0086	1.74e-49	166.0	COG3153@1|root,COG3153@2|Bacteria,1RHPP@1224|Proteobacteria,2U9DM@28211|Alphaproteobacteria,4BQZB@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	S	Acetyltransferase (GNAT) domain	-	-	-	ko:K03824	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_1,Acetyltransf_7,Acetyltransf_9
k141_3104_1	292459.STH3243	2.62e-06	48.9	COG1171@1|root,COG1171@2|Bacteria,1TP22@1239|Firmicutes,248D5@186801|Clostridia	186801|Clostridia	E	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA	ilvA	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT_4,PALP
k141_5570_1	522373.Smlt3402	8.49e-77	241.0	COG0649@1|root,COG0649@2|Bacteria,1MVIN@1224|Proteobacteria,1RM98@1236|Gammaproteobacteria,1X3JR@135614|Xanthomonadales	135614|Xanthomonadales	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoD	-	1.6.5.3	ko:K00333	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa,Complex1_49kDa
k141_5570_2	1500893.JQNB01000001_gene3173	8.18e-10	57.8	COG1905@1|root,COG1905@2|Bacteria,1MWS2@1224|Proteobacteria,1RN4C@1236|Gammaproteobacteria,1X3TC@135614|Xanthomonadales	135614|Xanthomonadales	C	NADH dehydrogenase	nuoE	-	1.6.5.3	ko:K00334	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx
k141_636_1	1121085.AUCI01000001_gene3431	2.24e-48	171.0	COG3333@1|root,COG3333@2|Bacteria,1TPE7@1239|Firmicutes,4HADN@91061|Bacilli,1ZBVK@1386|Bacillus	91061|Bacilli	S	Tripartite tricarboxylate transporter TctA family	-	-	-	-	-	-	-	-	-	-	-	-	TctA,TctB
k141_1871_1	439496.RBY4I_3797	9.46e-37	125.0	COG3436@1|root,COG3436@2|Bacteria,1RHDW@1224|Proteobacteria,2U7TH@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	IS66 Orf2 family protein	-	-	-	ko:K07484	-	-	-	-	ko00000	-	-	-	TnpB_IS66
k141_1871_2	1247963.JPHU01000004_gene625	1.23e-08	58.5	COG2433@1|root,COG2433@2|Bacteria,1RJ1Q@1224|Proteobacteria,2U9U2@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS66,DDE_Tnp_IS66_C,LZ_Tnp_IS66,zf-IS66
k141_6806_1	570952.ATVH01000014_gene1999	1.82e-38	135.0	COG0400@1|root,COG0400@2|Bacteria,1RA02@1224|Proteobacteria,2TTWP@28211|Alphaproteobacteria,2JS63@204441|Rhodospirillales	204441|Rhodospirillales	S	Phospholipase/Carboxylesterase	-	-	-	ko:K06999	-	-	-	-	ko00000	-	-	-	Abhydrolase_2
k141_6806_2	983920.Y88_3647	2.85e-24	97.8	COG0122@1|root,COG0122@2|Bacteria,1MX9C@1224|Proteobacteria,2TVJ7@28211|Alphaproteobacteria,2K0I0@204457|Sphingomonadales	204457|Sphingomonadales	L	COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase	-	-	3.2.2.21	ko:K01247	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD
k141_8646_1	390874.Tpet_0358	1.87e-72	236.0	COG0500@1|root,COG1181@1|root,COG1181@2|Bacteria,COG2226@2|Bacteria,2GBZA@200918|Thermotogae	200918|Thermotogae	F	Belongs to the D-alanine--D-alanine ligase family	-	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Methyltransf_25
k141_21_1	765913.ThidrDRAFT_0914	2.71e-27	114.0	COG4235@1|root,COG4235@2|Bacteria,1MY4J@1224|Proteobacteria,1RZEA@1236|Gammaproteobacteria,1WWTV@135613|Chromatiales	135613|Chromatiales	O	TIGRFAM Cytochrome c-type biogenesis protein CcmI	-	-	-	ko:K02200	-	-	-	-	ko00000	-	-	-	TPR_16,TPR_2
k141_637_1	384765.SIAM614_00165	4.86e-82	252.0	COG3547@1|root,COG3547@2|Bacteria,1MUER@1224|Proteobacteria,2TQTP@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	Transposase	-	-	-	ko:K07486	-	-	-	-	ko00000	-	-	-	DEDD_Tnp_IS110,Transposase_20
k141_1872_1	1278307.KB906967_gene2490	2.04e-108	325.0	COG3004@1|root,COG3004@2|Bacteria,1MW15@1224|Proteobacteria,1RNDE@1236|Gammaproteobacteria,2QHKE@267894|Psychromonadaceae	1236|Gammaproteobacteria	P	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons	nhaA	-	-	ko:K03313	-	-	-	-	ko00000,ko02000	2.A.33.1	-	-	Na_H_antiport_1
k141_4958_1	1356854.N007_00005	1.45e-79	253.0	COG1190@1|root,COG1190@2|Bacteria,1TP2P@1239|Firmicutes,4H9X4@91061|Bacilli,2791D@186823|Alicyclobacillaceae	91061|Bacilli	J	Belongs to the class-II aminoacyl-tRNA synthetase family	lysS	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
k141_23_1	1343158.SACS_1737	8.89e-107	317.0	COG0468@1|root,COG0468@2|Bacteria,1MU3C@1224|Proteobacteria,2TRPR@28211|Alphaproteobacteria,2JPIZ@204441|Rhodospirillales	204441|Rhodospirillales	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	-	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
k141_6808_1	1123392.AQWL01000001_gene1548	1.25e-37	142.0	COG1538@1|root,COG1538@2|Bacteria,1R7SQ@1224|Proteobacteria,2WBP4@28216|Betaproteobacteria,1KSAD@119069|Hydrogenophilales	119069|Hydrogenophilales	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
k141_9272_1	396588.Tgr7_0191	1.42e-110	343.0	COG0550@1|root,COG0550@2|Bacteria,1MUFZ@1224|Proteobacteria,1RNZ2@1236|Gammaproteobacteria,1WWWP@135613|Chromatiales	135613|Chromatiales	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topo_Zn_Ribbon,Topoisom_bac,Toprim,Toprim_C_rpt,zf-C4_Topoisom
k141_5573_1	472759.Nhal_3799	5.25e-101	299.0	COG0730@1|root,COG0730@2|Bacteria,1R712@1224|Proteobacteria,1S6UI@1236|Gammaproteobacteria,1WXAK@135613|Chromatiales	135613|Chromatiales	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
k141_3723_1	1535422.ND16A_1363	3.21e-98	308.0	28HMZ@1|root,2Z7WD@2|Bacteria,1MU3Q@1224|Proteobacteria,1RRUM@1236|Gammaproteobacteria,2Q6Y5@267889|Colwelliaceae	1236|Gammaproteobacteria	S	Protein of unknown function (DUF3604)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3604
k141_4959_1	1121374.KB891588_gene3291	8.18e-122	364.0	COG4147@1|root,COG4147@2|Bacteria,1MVJ8@1224|Proteobacteria,1RN0R@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	actP	-	-	ko:K14393	-	-	-	-	ko00000,ko02000	2.A.21.7	-	-	SSF
k141_8031_1	305900.GV64_01175	6.85e-146	428.0	COG2303@1|root,COG2303@2|Bacteria,1MV19@1224|Proteobacteria,1RMD2@1236|Gammaproteobacteria,1XHHA@135619|Oceanospirillales	135619|Oceanospirillales	E	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate	betA	-	1.1.99.1	ko:K00108	ko00260,ko01100,map00260,map01100	M00555	R01025	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	GMC_oxred_C,GMC_oxred_N
k141_640_1	1178825.ALIH01000013_gene542	2.82e-63	215.0	COG3292@1|root,COG3292@2|Bacteria,4NDWE@976|Bacteroidetes,1HY9S@117743|Flavobacteriia	976|Bacteroidetes	T	periplasmic ligand-binding sensor domain	-	-	-	-	-	-	-	-	-	-	-	-	Reg_prop
k141_7417_1	1269813.ATUL01000008_gene1531	3.32e-76	238.0	COG0082@1|root,COG0082@2|Bacteria,1MU98@1224|Proteobacteria,1RMQS@1236|Gammaproteobacteria,1WXNW@135613|Chromatiales	135613|Chromatiales	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	-	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_synt
k141_2495_1	159749.K0SZZ0	1.34e-12	72.8	COG2801@1|root,KOG0017@2759|Eukaryota,2XHT0@2836|Bacillariophyta	159749.K0SZZ0|-	O	transposition, RNA-mediated	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_3724_1	7029.ACYPI088512-PA	4.2e-20	94.4	COG2801@1|root,KOG0017@2759|Eukaryota,38DPC@33154|Opisthokonta,3BGB6@33208|Metazoa,3D5G4@33213|Bilateria,41ZUZ@6656|Arthropoda,3SKEY@50557|Insecta	33208|Metazoa	L	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	RVT_2,Retrotran_gag_2,gag_pre-integrs,rve
k141_1260_1	522373.Smlt0567	4.22e-23	102.0	COG0665@1|root,COG0665@2|Bacteria,1MVIZ@1224|Proteobacteria,1RQ50@1236|Gammaproteobacteria,1X45Z@135614|Xanthomonadales	135614|Xanthomonadales	E	Oxidative deamination of D-amino acids	dadA	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006520,GO:0006522,GO:0006524,GO:0006807,GO:0008150,GO:0008152,GO:0008718,GO:0009056,GO:0009063,GO:0009078,GO:0009080,GO:0009987,GO:0016020,GO:0016054,GO:0016491,GO:0016638,GO:0019478,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046144,GO:0046395,GO:0046416,GO:0046436,GO:0055114,GO:0055130,GO:0071704,GO:0071944,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	1.4.5.1	ko:K00285	ko00360,map00360	-	R01374,R09493	RC00006,RC00025	ko00000,ko00001,ko01000	-	-	-	DAO
k141_4960_1	1229909.NSED_01615	2.19e-89	276.0	COG1032@1|root,arCOG01357@2157|Archaea,41S86@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
k141_9274_1	1346791.M529_18385	1.05e-64	200.0	COG3293@1|root,COG3293@2|Bacteria,1N13W@1224|Proteobacteria	1224|Proteobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_2,DUF4096
k141_8649_1	1569209.BBPH01000095_gene1455	8.34e-31	117.0	COG2721@1|root,COG2721@2|Bacteria,1MU9V@1224|Proteobacteria,2TTDT@28211|Alphaproteobacteria,2PV4X@265|Paracoccus	28211|Alphaproteobacteria	G	D-galactarate dehydratase / Altronate hydrolase, C terminus	garD	-	4.2.1.7,4.4.1.24	ko:K16846,ko:K16850	ko00040,ko00270,ko01100,map00040,map00270,map01100	M00631	R01540,R07633	RC00543,RC01785	ko00000,ko00001,ko00002,ko01000	-	-	-	GD_AH_C
k141_8649_2	52598.EE36_11054	5.77e-47	165.0	COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,2TQND@28211|Alphaproteobacteria,3ZVWP@60136|Sulfitobacter	28211|Alphaproteobacteria	H	Aminotransferase class-III	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_3
k141_6190_2	412597.AEPN01000009_gene1773	4.26e-42	149.0	COG0477@1|root,COG2814@2|Bacteria,1MW59@1224|Proteobacteria,2TRA3@28211|Alphaproteobacteria,2PUJP@265|Paracoccus	28211|Alphaproteobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
k141_3725_1	2340.JV46_05690	6.49e-57	188.0	COG2826@1|root,COG2826@2|Bacteria,1PP49@1224|Proteobacteria,1RN7B@1236|Gammaproteobacteria,1JBRQ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	L	L COG2826 Transposase and inactivated derivatives, IS30 family	insI	GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0004803,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006310,GO:0006313,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0030983,GO:0032135,GO:0032196,GO:0032991,GO:0032993,GO:0034641,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363	-	ko:K07482	-	-	-	-	ko00000	-	-	-	HTH_38,rve
k141_4449_1	519989.ECTPHS_00150	2.58e-62	205.0	COG4536@1|root,COG4536@2|Bacteria,1NZ99@1224|Proteobacteria,1RNCE@1236|Gammaproteobacteria,1WWQM@135613|Chromatiales	135613|Chromatiales	P	CBS domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,DUF21
k141_8117_1	1316936.K678_10285	3.05e-95	286.0	COG0031@1|root,COG0031@2|Bacteria,1MUBE@1224|Proteobacteria,2TS33@28211|Alphaproteobacteria,2JQG3@204441|Rhodospirillales	204441|Rhodospirillales	E	Cysteine synthase	cysK	-	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
k141_123_1	1121033.AUCF01000031_gene96	2.48e-88	277.0	COG3243@1|root,COG3243@2|Bacteria,1MU68@1224|Proteobacteria,2TR7S@28211|Alphaproteobacteria,2JQCH@204441|Rhodospirillales	204441|Rhodospirillales	I	Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus	phbC	-	-	ko:K03821	ko00650,map00650	-	R04254	RC00004	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1,PhaC_N
k141_743_1	331869.BAL199_28445	7.05e-126	365.0	COG0330@1|root,COG0330@2|Bacteria,1MV7R@1224|Proteobacteria,2TRP4@28211|Alphaproteobacteria,4BPGN@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	O	HflC and HflK could regulate a protease	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
k141_8907_1	159749.E7BWK3	5.14e-40	133.0	COG1145@1|root,2S26M@2759|Eukaryota,2XGSJ@2836|Bacillariophyta	2836|Bacillariophyta	C	essential for photochemical activity. FB is the terminal electron acceptor of PSI, donating electrons to ferredoxin. The C-terminus interacts with PsaA B D and helps assemble the protein into the PSI complex. Required for binding of PsaD and PsaE to PSI. PSI is a plastocyanin cytochrome c6- ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn	psaC	-	-	ko:K02691	ko00195,ko01100,map00195,map01100	M00163	-	-	ko00000,ko00001,ko00002,ko00194	-	-	-	Fer4
k141_8907_2	35128.Thapsdraft1620	3.4e-122	353.0	COG2022@1|root,2RCR5@2759|Eukaryota,2XEJ1@2836|Bacillariophyta	2836|Bacillariophyta	H	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S	thiG	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009536,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464	-	-	-	-	-	-	-	-	-	-	ThiG
k141_9560_1	1056820.KB900630_gene1428	6.11e-98	307.0	COG1674@1|root,COG1674@2|Bacteria,1MVPI@1224|Proteobacteria,1RM9A@1236|Gammaproteobacteria,2PMX1@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	D	FtsK/SpoIIIE family	ftsK	GO:0000920,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006355,GO:0006950,GO:0006970,GO:0007059,GO:0008094,GO:0008150,GO:0009628,GO:0009651,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0015616,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019219,GO:0019222,GO:0031224,GO:0031226,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0033676,GO:0042221,GO:0042623,GO:0042802,GO:0043085,GO:0043565,GO:0044093,GO:0044425,GO:0044459,GO:0044464,GO:0045893,GO:0045935,GO:0046677,GO:0048518,GO:0048522,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051301,GO:0051716,GO:0060255,GO:0065007,GO:0065009,GO:0070887,GO:0071236,GO:0071944,GO:0080090,GO:0097159,GO:0140097,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
k141_5868_1	367336.OM2255_06590	8.62e-90	291.0	COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,2TS2I@28211|Alphaproteobacteria	28211|Alphaproteobacteria	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	nrdJ	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_2_N,Ribonuc_red_lgC
k141_7666_1	1229909.NSED_02465	1.95e-13	67.8	COG0007@1|root,arCOG00644@2157|Archaea,41S9J@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Belongs to the precorrin methyltransferase family	-	-	2.1.1.107	ko:K02303	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03194	RC00003,RC00871	ko00000,ko00001,ko00002,ko01000	-	-	-	TP_methylase
k141_7666_2	1229909.NSED_02460	2.16e-95	285.0	COG0181@1|root,arCOG04299@2157|Archaea,41S6Z@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps	hemC	-	2.5.1.61	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084	RC02317	ko00000,ko00001,ko00002,ko01000	-	-	-	Porphobil_deam,Porphobil_deamC
k141_4020_1	2880.D7FN76	1.09e-08	59.3	COG2119@1|root,KOG2881@2759|Eukaryota	2759|Eukaryota	L	Golgi calcium ion transport	TMEM165	GO:0000041,GO:0000139,GO:0000322,GO:0000323,GO:0000324,GO:0000329,GO:0003674,GO:0005215,GO:0005384,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005764,GO:0005765,GO:0005768,GO:0005769,GO:0005770,GO:0005773,GO:0005774,GO:0005794,GO:0005795,GO:0005797,GO:0005801,GO:0005802,GO:0006464,GO:0006486,GO:0006487,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0006816,GO:0006828,GO:0006873,GO:0006874,GO:0006875,GO:0006885,GO:0006996,GO:0007033,GO:0007040,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009987,GO:0010008,GO:0012505,GO:0015075,GO:0015077,GO:0015078,GO:0015085,GO:0015291,GO:0015297,GO:0015298,GO:0015299,GO:0015318,GO:0015368,GO:0015369,GO:0015491,GO:0015672,GO:0016020,GO:0016021,GO:0016043,GO:0019538,GO:0019725,GO:0022804,GO:0022857,GO:0022890,GO:0030001,GO:0030003,GO:0030004,GO:0030641,GO:0031090,GO:0031224,GO:0031410,GO:0031901,GO:0031902,GO:0031982,GO:0031984,GO:0031985,GO:0032468,GO:0032472,GO:0032588,GO:0034220,GO:0034645,GO:0035751,GO:0036211,GO:0042592,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044425,GO:0044431,GO:0044433,GO:0044437,GO:0044440,GO:0044444,GO:0044446,GO:0044464,GO:0046873,GO:0046915,GO:0048878,GO:0050801,GO:0051139,GO:0051179,GO:0051234,GO:0051453,GO:0055065,GO:0055067,GO:0055074,GO:0055080,GO:0055082,GO:0055085,GO:0061856,GO:0065007,GO:0065008,GO:0070085,GO:0070588,GO:0070838,GO:0071421,GO:0071704,GO:0071840,GO:0072503,GO:0072507,GO:0072511,GO:0080171,GO:0097708,GO:0098588,GO:0098655,GO:0098660,GO:0098662,GO:0098771,GO:0098791,GO:0098805,GO:0098852,GO:0099516,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	-	-	-	-	-	-	-	-	-	UPF0016
k141_2786_1	1385935.N836_14770	1.38e-27	107.0	COG0522@1|root,COG0522@2|Bacteria,1G03U@1117|Cyanobacteria,1H6WF@1150|Oscillatoriales	1117|Cyanobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rps4	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
k141_2786_2	756067.MicvaDRAFT_3504	1.72e-19	82.0	COG0228@1|root,COG0228@2|Bacteria,1G7XN@1117|Cyanobacteria,1HC4K@1150|Oscillatoriales	1117|Cyanobacteria	J	Belongs to the bacterial ribosomal protein bS16 family	rpsP	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02959	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S16
k141_323_1	1163617.SCD_n01585	6.45e-85	266.0	COG1032@1|root,COG1032@2|Bacteria,1MUMS@1224|Proteobacteria,2VZ32@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
k141_4644_1	314271.RB2654_07321	7.08e-27	105.0	COG1028@1|root,COG1028@2|Bacteria,1MVQW@1224|Proteobacteria,2TTD0@28211|Alphaproteobacteria	28211|Alphaproteobacteria	IQ	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	-	-	1.1.1.304,1.1.1.76	ko:K03366	ko00650,map00650	-	R02855,R02946,R03707,R09078,R10505	RC00205,RC00525	ko00000,ko00001,ko01000	-	-	-	adh_short_C2
k141_4644_2	391626.OAN307_c40920	2.59e-54	178.0	COG1879@1|root,COG1879@2|Bacteria,1NRXG@1224|Proteobacteria,2TW5I@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	ABC-type sugar transport system periplasmic component	MA20_14320	-	-	ko:K10439,ko:K17202,ko:K17205,ko:K17213	ko02010,ko02030,map02010,map02030	M00212,M00590,M00591,M00593	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2,3.A.1.2.1,3.A.1.2.11,3.A.1.2.13,3.A.1.2.15,3.A.1.2.16,3.A.1.2.19	-	-	Peripla_BP_4
k141_8908_1	1307759.JOMJ01000003_gene2337	6.6e-13	68.2	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2WJVV@28221|Deltaproteobacteria,2M817@213115|Desulfovibrionales	28221|Deltaproteobacteria	V	TIGRFAM transporter, hydrophobe amphiphile efflux-1 (HAE1) family	-	-	-	ko:K03296,ko:K18138	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
k141_8908_2	335543.Sfum_3921	6.63e-32	124.0	COG0845@1|root,COG0845@2|Bacteria,1MU78@1224|Proteobacteria,42P19@68525|delta/epsilon subdivisions,2WK00@28221|Deltaproteobacteria,2MR1N@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K19595	-	M00768,M00769	-	-	ko00000,ko00002,ko01504,ko02000	2.A.6.2.25,2.A.6.2.34,8.A.1	-	-	Biotin_lipoyl_2,HlyD_D23
k141_9561_1	484770.UFO1_1843	4.55e-58	203.0	COG0493@1|root,COG1145@1|root,COG0493@2|Bacteria,COG1145@2|Bacteria,1TPR4@1239|Firmicutes,4H9C5@909932|Negativicutes	909932|Negativicutes	CE	Selenate reductase	-	-	1.97.1.9	ko:K12527	ko00450,map00450	-	R07229	RC02420	ko00000,ko00001,ko01000	-	-	-	Fer4_20,NAD_binding_8,Pyr_redox_2
k141_7667_1	1231392.OCGS_0340	5.56e-53	175.0	COG0803@1|root,COG0803@2|Bacteria,1MVW9@1224|Proteobacteria,2TQTF@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	Belongs to the bacterial solute-binding protein 9 family	sitA	-	-	ko:K02077,ko:K09815,ko:K11604	ko02010,map02010	M00242,M00244,M00317	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15,3.A.1.15.3,3.A.1.15.5,3.A.1.15.7,3.A.1.15.9	-	-	ZnuA
k141_1556_1	159749.E7BWI1	1.18e-175	499.0	COG1850@1|root,2QTI9@2759|Eukaryota,2XE5R@2836|Bacillariophyta	2836|Bacillariophyta	Q	RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process. Both reactions occur simultaneously and in competition at the same active site	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009536,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464	4.1.1.39	ko:K01601	ko00630,ko00710,ko01100,ko01120,ko01200,map00630,map00710,map01100,map01120,map01200	M00165,M00166,M00532	R00024,R03140	RC00172,RC00859	ko00000,ko00001,ko00002,ko01000	-	-	-	RuBisCO_large,RuBisCO_large_N
k141_3381_1	4096.XP_009781880.1	1.27e-13	84.0	COG2801@1|root,KOG0017@2759|Eukaryota,37RIF@33090|Viridiplantae	33090|Viridiplantae	O	Cysteine-rich RLK (RECEPTOR-like protein kinase) 8	-	-	-	-	-	-	-	-	-	-	-	-	RVT_2,Retrotran_gag_2,Retrotran_gag_3,Retrotrans_gag,gag_pre-integrs,rve
k141_324_1	83219.PM02_00175	6.27e-96	301.0	COG3264@1|root,COG3264@2|Bacteria,1MWSA@1224|Proteobacteria,2TRKK@28211|Alphaproteobacteria,3ZV00@60136|Sulfitobacter	28211|Alphaproteobacteria	M	Protein of unknown function (DUF3772)	kefA	-	-	ko:K05802	-	-	-	-	ko00000,ko02000	1.A.23.1.1	-	-	DUF3772,MS_channel
k141_9562_1	1207063.P24_11440	4.67e-109	328.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,2TQR1@28211|Alphaproteobacteria,2JPSC@204441|Rhodospirillales	204441|Rhodospirillales	C	belongs to the aldehyde dehydrogenase family	gabD	-	1.2.1.16,1.2.1.20,1.2.1.79	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	M00027	R00713,R00714,R02401	RC00080	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
k141_6497_1	565045.NOR51B_2247	1.39e-15	76.3	COG1629@1|root,COG4773@1|root,COG1629@2|Bacteria,COG4773@2|Bacteria,1QTXJ@1224|Proteobacteria,1T1MR@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	COG1629 Outer membrane receptor proteins, mostly Fe transport	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
k141_7103_1	314262.MED193_18284	4.56e-79	249.0	COG4638@1|root,COG4638@2|Bacteria,1MWXW@1224|Proteobacteria,2TVNW@28211|Alphaproteobacteria,2P23N@2433|Roseobacter	28211|Alphaproteobacteria	P	COG4638 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit	-	-	1.14.13.239,1.14.15.7	ko:K00499,ko:K22443	ko00260,map00260	-	R07409	RC00087	ko00000,ko00001,ko01000	-	-	-	Rieske,Ring_hydroxyl_A
k141_4646_1	1188256.BASI01000002_gene3694	1.19e-26	112.0	COG0144@1|root,COG0144@2|Bacteria,1MV2Q@1224|Proteobacteria,2TS6U@28211|Alphaproteobacteria,3FD13@34008|Rhodovulum	28211|Alphaproteobacteria	J	16S rRNA methyltransferase RsmB/F	sun1	-	2.1.1.176	ko:K03500	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F
k141_4022_1	754476.Q7A_2480	5.33e-93	298.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,1RNBG@1236|Gammaproteobacteria,45ZUW@72273|Thiotrichales	72273|Thiotrichales	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
k141_5871_1	1469245.JFBG01000023_gene1240	9.7e-36	135.0	COG2379@1|root,COG2379@2|Bacteria,1MVIK@1224|Proteobacteria,1RPKA@1236|Gammaproteobacteria,1WXPP@135613|Chromatiales	135613|Chromatiales	G	pfam mofrl	-	-	2.7.1.165	ko:K11529	ko00030,ko00260,ko00561,ko00630,ko00680,ko01100,ko01120,ko01130,ko01200,map00030,map00260,map00561,map00630,map00680,map01100,map01120,map01130,map01200	M00346	R08572	RC00002,RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF4147,MOFRL
k141_2180_1	1207063.P24_10690	7.86e-42	151.0	COG1171@1|root,COG1171@2|Bacteria,1MVWJ@1224|Proteobacteria,2TQN9@28211|Alphaproteobacteria,2JPM3@204441|Rhodospirillales	204441|Rhodospirillales	E	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA	ilvA	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,ACT_4,PALP
k141_326_1	583355.Caka_0724	1.44e-77	246.0	COG1219@1|root,COG1219@2|Bacteria,46SIK@74201|Verrucomicrobia,3K7MK@414999|Opitutae	414999|Opitutae	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	-	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
k141_9565_1	349521.HCH_04903	2.77e-21	93.2	COG3637@1|root,COG3637@2|Bacteria,1R3QN@1224|Proteobacteria,1RY3J@1236|Gammaproteobacteria,1XKR9@135619|Oceanospirillales	135619|Oceanospirillales	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_1560_1	1005048.CFU_0662	1.89e-48	166.0	COG2857@1|root,COG2857@2|Bacteria,1QFU2@1224|Proteobacteria,2VIR6@28216|Betaproteobacteria,473AB@75682|Oxalobacteraceae	28216|Betaproteobacteria	P	Cytochrome C1	petC	-	-	ko:K00413	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002	-	-	-	Cytochrom_C1
k141_1560_2	90814.KL370891_gene518	1.25e-36	135.0	COG1290@1|root,COG1290@2|Bacteria,1MV97@1224|Proteobacteria,1RNCP@1236|Gammaproteobacteria,45ZV4@72273|Thiotrichales	72273|Thiotrichales	C	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis	-	-	-	ko:K00412	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002,ko03029	-	-	-	Cytochrom_B_C,Cytochrome_B
k141_4025_1	272943.RSP_2178	6.31e-13	68.2	COG0550@1|root,COG1754@1|root,COG0550@2|Bacteria,COG1754@2|Bacteria,1MUFZ@1224|Proteobacteria,2TRGN@28211|Alphaproteobacteria,1FB00@1060|Rhodobacter	28211|Alphaproteobacteria	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,Toprim_C_rpt,zf-C4_Topoisom
k141_4025_2	1188256.BASI01000003_gene2821	2.68e-47	169.0	COG0550@1|root,COG1754@1|root,COG0550@2|Bacteria,COG1754@2|Bacteria,1MUFZ@1224|Proteobacteria,2TRGN@28211|Alphaproteobacteria,3FCQB@34008|Rhodovulum	28211|Alphaproteobacteria	G	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,Toprim_C_rpt,zf-C4_Topoisom
k141_4649_2	1240350.AMZE01000092_gene667	2.69e-30	119.0	COG0480@1|root,COG0480@2|Bacteria,1MUCV@1224|Proteobacteria,1RNSZ@1236|Gammaproteobacteria,1YUYU@136845|Pseudomonas putida group	1236|Gammaproteobacteria	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
k141_7106_1	1247726.MIM_c14540	1.41e-31	119.0	COG0846@1|root,COG0846@2|Bacteria,1MUK1@1224|Proteobacteria,2VJUU@28216|Betaproteobacteria,3T1DF@506|Alcaligenaceae	28216|Betaproteobacteria	K	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form	cobB	-	-	-	-	-	-	-	-	-	-	-	SIR2
k141_5874_1	1392488.JHZY01000004_gene2948	1.02e-05	50.1	COG0741@1|root,COG1388@1|root,COG0741@2|Bacteria,COG1388@2|Bacteria,4NEKW@976|Bacteroidetes,1HYXP@117743|Flavobacteriia,2XI8M@283735|Leeuwenhoekiella	976|Bacteroidetes	M	Transglycosylase SLT domain	mltD	-	-	ko:K08307	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	LysM,SLT
k141_5874_2	391615.ABSJ01000026_gene110	4.21e-20	90.9	COG0607@1|root,COG0664@1|root,COG0607@2|Bacteria,COG0664@2|Bacteria,1R9Q1@1224|Proteobacteria,1RSKD@1236|Gammaproteobacteria,1J6A4@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	PT	COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese,cNMP_binding
k141_2792_1	1197906.CAJQ02000003_gene3255	4.61e-138	400.0	COG3666@1|root,COG3666@2|Bacteria,1N3QR@1224|Proteobacteria,2TRXG@28211|Alphaproteobacteria,3JVHX@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	L	Transposase	-	-	-	ko:K07487	-	-	-	-	ko00000	-	-	-	DDE_Tnp_1,DDE_Tnp_1_6,DUF772
k141_942_1	159749.K0T947	1.57e-17	82.4	KOG4585@1|root,KOG4585@2759|Eukaryota,2XGAU@2836|Bacillariophyta	2836|Bacillariophyta	S	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_4
k141_1000_1	2880.D1J768	7.9e-10	56.2	COG0211@1|root,KOG4600@2759|Eukaryota	2759|Eukaryota	J	structural constituent of ribosome	rpl27	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009507,GO:0009526,GO:0009532,GO:0009536,GO:0009570,GO:0009579,GO:0009719,GO:0009725,GO:0009735,GO:0009941,GO:0010033,GO:0031967,GO:0031975,GO:0042221,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0050896	-	ko:K02899	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27
k141_1000_2	321327.CYA_2052	3.67e-21	88.6	COG0261@1|root,COG0261@2|Bacteria,1G6RH@1117|Cyanobacteria,1H0F6@1129|Synechococcus	1117|Cyanobacteria	J	This protein binds to 23S rRNA in the presence of protein L20	rplU	GO:0003674,GO:0003735,GO:0005198	-	ko:K02888	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L21p
k141_4090_1	28229.ND2E_3718	8.62e-28	106.0	2DN04@1|root,32UP0@2|Bacteria,1N3MR@1224|Proteobacteria,1SARX@1236|Gammaproteobacteria,2Q89Y@267889|Colwelliaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_2245_1	1329516.JPST01000021_gene2398	2.01e-08	59.3	COG1737@1|root,COG1737@2|Bacteria,1TP7H@1239|Firmicutes,4HE40@91061|Bacilli,27D05@186824|Thermoactinomycetaceae	91061|Bacilli	K	Helix-turn-helix domain, rpiR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_6,SIS
k141_5936_2	1178825.ALIH01000005_gene153	1.25e-15	75.1	COG0116@1|root,COG0116@2|Bacteria,4NFJM@976|Bacteroidetes,1HZBE@117743|Flavobacteriia	976|Bacteroidetes	L	Belongs to the methyltransferase superfamily	rlmL	-	-	ko:K07444	-	-	-	-	ko00000,ko01000	-	-	-	THUMP,UPF0020
k141_9619_1	314262.MED193_15972	9.73e-45	152.0	COG2801@1|root,COG2801@2|Bacteria,1MVC8@1224|Proteobacteria,2TRX0@28211|Alphaproteobacteria,2P1JZ@2433|Roseobacter	28211|Alphaproteobacteria	L	COG2801 Transposase and inactivated derivatives	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve
k141_9619_2	633131.TR2A62_1822	3.48e-52	165.0	COG2963@1|root,COG2963@2|Bacteria,1N06K@1224|Proteobacteria,2UAJI@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	COG2963 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Tnp_1
k141_2858_2	1027273.GZ77_11140	2.9e-12	70.5	2DA4I@1|root,32TUN@2|Bacteria,1N0WK@1224|Proteobacteria,1S6HI@1236|Gammaproteobacteria,1XK37@135619|Oceanospirillales	135619|Oceanospirillales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_6556_1	56110.Oscil6304_5387	1.89e-11	59.7	COG0333@1|root,COG0333@2|Bacteria,1G8ZP@1117|Cyanobacteria,1HCSZ@1150|Oscillatoriales	1117|Cyanobacteria	J	Belongs to the bacterial ribosomal protein bL32 family	rpmF	-	-	ko:K02911	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_L32p
k141_391_1	1282876.BAOK01000001_gene3447	8.49e-105	329.0	COG2937@1|root,COG2937@2|Bacteria,1MWZ6@1224|Proteobacteria	1224|Proteobacteria	I	Belongs to the GPAT DAPAT family	-	-	2.3.1.15	ko:K00631	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
k141_8964_1	768671.ThimaDRAFT_1300	4.67e-44	152.0	COG1714@1|root,COG1714@2|Bacteria,1RIE9@1224|Proteobacteria,1S566@1236|Gammaproteobacteria,1WY4A@135613|Chromatiales	135613|Chromatiales	S	RDD family	-	-	-	-	-	-	-	-	-	-	-	-	RDD
k141_4092_1	1288298.rosmuc_02416	5.81e-50	164.0	2E4Q0@1|root,32ZIM@2|Bacteria,1N6SU@1224|Proteobacteria,2UFRW@28211|Alphaproteobacteria,46PBC@74030|Roseovarius	28211|Alphaproteobacteria	S	Heavy-metal resistance	-	-	-	-	-	-	-	-	-	-	-	-	Metal_resist
k141_3452_1	1265503.KB905161_gene3234	2e-74	240.0	COG1404@1|root,COG1404@2|Bacteria,1N6G1@1224|Proteobacteria,1RSME@1236|Gammaproteobacteria,2Q5UQ@267889|Colwelliaceae	1236|Gammaproteobacteria	O	Subtilase family	-	-	-	ko:K17734	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S8
k141_1625_1	379731.PST_2311	2.05e-79	254.0	COG2224@1|root,COG2224@2|Bacteria,1MWIF@1224|Proteobacteria,1RQAK@1236|Gammaproteobacteria,1Z0SC@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	C	Isocitrate lyase	aceA	-	4.1.3.1	ko:K01637	ko00630,ko01100,ko01110,ko01120,ko01200,map00630,map01100,map01110,map01120,map01200	M00012	R00479	RC00311,RC00313	ko00000,ko00001,ko00002,ko01000	-	-	-	ICL
k141_7172_1	420324.KI911984_gene5121	3.61e-55	182.0	COG3547@1|root,COG3547@2|Bacteria,1QYJU@1224|Proteobacteria,2U1TU@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k141_5330_1	570268.ANBB01000037_gene2798	9.6e-11	67.4	COG0145@1|root,COG0145@2|Bacteria,2GIYE@201174|Actinobacteria,4EGC9@85012|Streptosporangiales	201174|Actinobacteria	EQ	Hydantoinase/oxoprolinase N-terminal region	-	-	3.5.2.14	ko:K01473	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydant_A_N,Hydantoinase_A
k141_9621_1	1089551.KE386572_gene2100	1.63e-53	182.0	COG0213@1|root,COG0213@2|Bacteria,1MV3H@1224|Proteobacteria,2TS24@28211|Alphaproteobacteria,4BPPS@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	F	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis	deoA	-	2.4.2.4	ko:K00758	ko00240,ko00983,ko01100,ko05219,map00240,map00983,map01100,map05219	-	R01570,R02484,R08222,R08230	RC00063	ko00000,ko00001,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3,PYNP_C
k141_9621_2	1122137.AQXF01000005_gene1107	7.47e-29	112.0	COG5285@1|root,COG5285@2|Bacteria,1Q78R@1224|Proteobacteria,2TSX3@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	Phytanoyl-CoA dioxygenase (PhyH)	-	-	-	-	-	-	-	-	-	-	-	-	PhyH
k141_4713_1	1116472.MGMO_105c00320	4.84e-53	188.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1XH1W@135618|Methylococcales	135618|Methylococcales	T	Histidine Phosphotransfer domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,HAMP,HATPase_c,HisKA,Hpt,Response_reg
k141_1626_1	179408.Osc7112_2439	4.53e-15	82.0	COG2202@1|root,COG2203@1|root,COG3452@1|root,COG4191@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG3452@2|Bacteria,COG4191@2|Bacteria,1G1Z8@1117|Cyanobacteria,1H950@1150|Oscillatoriales	1117|Cyanobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,GAF_2,HATPase_c,HisKA,PAS_3,PAS_4
k141_5331_1	1300350.DSW25_01915	4.26e-13	67.8	COG2003@1|root,COG2003@2|Bacteria,1MXZ5@1224|Proteobacteria,2TQXM@28211|Alphaproteobacteria,3ZWGH@60136|Sulfitobacter	28211|Alphaproteobacteria	L	RadC-like JAB domain	radC	GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360	-	ko:K03630	-	-	-	-	ko00000	-	-	-	RadC
k141_2860_1	1247963.JPHU01000002_gene2631	3.06e-21	94.0	COG0016@1|root,COG0016@2|Bacteria,1MVD7@1224|Proteobacteria,2TS2T@28211|Alphaproteobacteria	28211|Alphaproteobacteria	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily	pheS	GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Phe_tRNA-synt_N,tRNA-synt_2d
k141_2860_2	1260251.SPISAL_03525	7.29e-26	98.6	COG0292@1|root,COG0292@2|Bacteria,1RGU2@1224|Proteobacteria,1S3P3@1236|Gammaproteobacteria,1WYQC@135613|Chromatiales	135613|Chromatiales	J	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit	rplT	-	-	ko:K02887	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L20
k141_1004_1	1380391.JIAS01000017_gene522	2.87e-64	198.0	COG0745@1|root,COG0745@2|Bacteria,1RDNP@1224|Proteobacteria,2U7BP@28211|Alphaproteobacteria,2JS99@204441|Rhodospirillales	204441|Rhodospirillales	KT	COG0784 FOG CheY-like receiver	-	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
k141_8967_1	1122180.Lokhon_02617	1.64e-60	201.0	COG1249@1|root,COG1249@2|Bacteria,1MU2Z@1224|Proteobacteria,2TQS7@28211|Alphaproteobacteria,2P8D9@245186|Loktanella	28211|Alphaproteobacteria	C	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain	gor	GO:0000166,GO:0000302,GO:0000305,GO:0003674,GO:0005488,GO:0005507,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009987,GO:0010035,GO:0017076,GO:0019725,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042221,GO:0042592,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0045454,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0065007,GO:0065008,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901700	1.8.1.7	ko:K00383	ko00480,ko04918,map00480,map04918	-	R00094,R00115	RC00011	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,Pyr_redox_dim
k141_2861_1	572477.Alvin_0031	1.69e-33	129.0	COG0187@1|root,COG1372@1|root,COG0187@2|Bacteria,COG1372@2|Bacteria,1MVKT@1224|Proteobacteria,1RNB2@1236|Gammaproteobacteria,1WVZ4@135613|Chromatiales	135613|Chromatiales	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
k141_2861_2	1370125.AUWT01000015_gene2583	5.83e-20	89.4	COG0188@1|root,COG0188@2|Bacteria,2GJ2Q@201174|Actinobacteria,233TD@1762|Mycobacteriaceae	201174|Actinobacteria	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017076,GO:0017111,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034335,GO:0034641,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0046872,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV,Intein_splicing,LAGLIDADG_3
k141_4203_1	159749.K0R708	4.84e-67	231.0	COG2801@1|root,KOG0017@2759|Eukaryota,2XF4I@2836|Bacillariophyta	159749.K0R708|-	L	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_9068_2	335541.Swol_0785	0.000349	45.4	COG3383@1|root,COG3383@2|Bacteria,1UI1F@1239|Firmicutes,25EAG@186801|Clostridia,42K9F@68298|Syntrophomonadaceae	186801|Clostridia	C	Molybdopterin oxidoreductase Fe4S4 domain	-	-	1.17.1.10,1.6.5.3	ko:K00336,ko:K05299	ko00190,ko00680,ko00720,ko01100,ko01120,ko01200,map00190,map00680,map00720,map01100,map01120,map01200	M00144,M00377	R00134,R11945	RC00061,RC02796	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,Fer4,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
k141_1732_1	595460.RRSWK_04836	1.08e-71	233.0	COG0055@1|root,COG0055@2|Bacteria,2IY7P@203682|Planctomycetes	203682|Planctomycetes	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
k141_2350_1	436308.Nmar_1131	2.87e-107	317.0	COG2132@1|root,arCOG03914@2157|Archaea,41S77@651137|Thaumarchaeota	651137|Thaumarchaeota	Q	PFAM Multicopper oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Cu-oxidase_2,Cu-oxidase_3
k141_499_1	571166.KI421509_gene1933	1.92e-20	85.5	2EB3A@1|root,33542@2|Bacteria,1NE82@1224|Proteobacteria,2UJ6C@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_4206_1	35128.Thapsdraft2050	1.23e-38	147.0	COG0086@1|root,2RUNH@2759|Eukaryota,2XF5V@2836|Bacillariophyta	2836|Bacillariophyta	H	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC2	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009536,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464	-	-	-	-	-	-	-	-	-	-	RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
k141_7841_1	1123037.AUDE01000025_gene3430	2.79e-93	295.0	COG0550@1|root,COG1754@1|root,COG0550@2|Bacteria,COG1754@2|Bacteria,4NF9S@976|Bacteroidetes,1HX5E@117743|Flavobacteriia	976|Bacteroidetes	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,Toprim_C_rpt
k141_2351_1	35128.Thapsdraft1611	2.8e-149	439.0	28JJ8@1|root,2QRYE@2759|Eukaryota,2XEB4@2836|Bacillariophyta	2836|Bacillariophyta	C	PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX. PSI is a plastocyanin cytochrome c6-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn. Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin or cytochrome c6	psaB	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009534,GO:0009535,GO:0009536,GO:0009579,GO:0016020,GO:0016168,GO:0031976,GO:0031984,GO:0034357,GO:0042651,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044436,GO:0044444,GO:0044446,GO:0044464,GO:0046906,GO:0048037,GO:0055035,GO:0097159,GO:1901363	-	ko:K02690	ko00195,ko01100,map00195,map01100	M00163	-	-	ko00000,ko00001,ko00002,ko00194	-	-	-	PsaA_PsaB
k141_6042_1	316055.RPE_3277	2.66e-69	225.0	COG0397@1|root,COG0397@2|Bacteria,1MVK3@1224|Proteobacteria,2TT84@28211|Alphaproteobacteria,3JTYR@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Belongs to the UPF0061 (SELO) family	MA20_28420	-	-	ko:K08997	-	-	-	-	ko00000	-	-	-	UPF0061
k141_2969_1	1122164.JHWF01000001_gene2012	3.57e-39	140.0	COG0407@1|root,COG0407@2|Bacteria,1MUG1@1224|Proteobacteria,1RMDH@1236|Gammaproteobacteria,1JD3S@118969|Legionellales	118969|Legionellales	H	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III	hemE	GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006536,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009064,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019353,GO:0019438,GO:0019752,GO:0033013,GO:0033014,GO:0033526,GO:0034641,GO:0042168,GO:0042440,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
k141_9727_1	322710.Avin_38400	2.09e-20	91.3	COG0589@1|root,COG0589@2|Bacteria,1MVZS@1224|Proteobacteria,1RPAE@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	universal stress protein	ydaA	-	-	ko:K14055	-	-	-	-	ko00000	-	-	-	Usp
k141_1114_1	1229909.NSED_01805	5.23e-166	488.0	COG0013@1|root,arCOG01255@2157|Archaea,41SBJ@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
k141_6043_1	196490.AUEZ01000019_gene521	5.96e-16	80.5	COG0725@1|root,COG0725@2|Bacteria,1PA2T@1224|Proteobacteria,2U1JI@28211|Alphaproteobacteria,3JUZJ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	P	Bacterial extracellular solute-binding protein	-	-	5.3.3.7	ko:K02020,ko:K22003	ko00660,ko02010,map00660,map02010	M00189	R02244	RC00668	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.8	-	-	SBP_bac_11
k141_3549_1	391589.RGAI101_2559	1.54e-93	279.0	COG1028@1|root,COG1028@2|Bacteria,1PEWK@1224|Proteobacteria,2TV4E@28211|Alphaproteobacteria	28211|Alphaproteobacteria	IQ	Short-chain dehydrogenase reductase SDR	MA20_40070	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
k141_9070_2	335659.S23_34660	1.78e-33	127.0	COG3293@1|root,COG3293@2|Bacteria,1PVIT@1224|Proteobacteria,2TURP@28211|Alphaproteobacteria,3JWWQ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	L	Putative transposase of IS4/5 family (DUF4096)	-	-	-	ko:K07492	-	-	-	-	ko00000	-	-	-	DDE_Tnp_1,DUF4096
k141_502_1	1122137.AQXF01000003_gene2151	5.13e-68	221.0	COG1288@1|root,COG1288@2|Bacteria,1MY1J@1224|Proteobacteria,2U2WN@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	C4-dicarboxylate	-	-	-	-	-	-	-	-	-	-	-	-	DcuC
k141_6044_1	639283.Snov_4113	1.67e-19	92.4	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2TR8X@28211|Alphaproteobacteria,3EZ5A@335928|Xanthobacteraceae	28211|Alphaproteobacteria	T	Signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_4,PAS_9
k141_1735_1	1354722.JQLS01000008_gene282	6.78e-106	322.0	COG5360@1|root,COG5360@2|Bacteria,1MUJ4@1224|Proteobacteria,2TR5G@28211|Alphaproteobacteria,46P0G@74030|Roseovarius	28211|Alphaproteobacteria	S	Heparinase II/III-like protein	MA20_25080	-	-	-	-	-	-	-	-	-	-	-	Hepar_II_III
k141_6667_1	765911.Thivi_3073	8.82e-100	300.0	COG1180@1|root,COG1180@2|Bacteria,1NQC1@1224|Proteobacteria,1T0C6@1236|Gammaproteobacteria,1WXH4@135613|Chromatiales	135613|Chromatiales	C	PFAM Radical SAM	-	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
k141_8477_1	936455.KI421499_gene4838	1.31e-22	95.5	COG1194@1|root,COG1194@2|Bacteria,1MUD4@1224|Proteobacteria,2TQVX@28211|Alphaproteobacteria,3JQMI@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	L	FES	mutY	GO:0003674,GO:0003824,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360	-	ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD,NUDIX_4
k141_8477_2	1122135.KB893134_gene3831	1.42e-26	103.0	COG5389@1|root,COG5389@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF721)	MA20_42435	-	-	-	-	-	-	-	-	-	-	-	DUF721
k141_2971_1	298654.FraEuI1c_3473	2.52e-16	83.6	COG0607@1|root,COG2897@1|root,COG0607@2|Bacteria,COG2897@2|Bacteria,2ICZ1@201174|Actinobacteria	201174|Actinobacteria	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
k141_6045_2	1411123.JQNH01000001_gene36	3.23e-49	170.0	COG0677@1|root,COG0677@2|Bacteria,1MUC6@1224|Proteobacteria,2TR5F@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	-	-	1.1.1.136	ko:K13015	ko00520,map00520	-	R00421	RC00291	ko00000,ko00001,ko01000,ko01005	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
k141_1736_1	3694.POPTR_0018s01380.1	3.36e-05	50.4	28P22@1|root,2QVNI@2759|Eukaryota,37SGH@33090|Viridiplantae,3GFX8@35493|Streptophyta,4JTZE@91835|fabids	35493|Streptophyta	J	Ribosomal protein S4	rps4	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0034248,GO:0034250,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:2000112	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S4
k141_3551_1	493475.GARC_1451	3.42e-06	48.9	COG1253@1|root,COG1253@2|Bacteria,1N0IQ@1224|Proteobacteria,1RY1D@1236|Gammaproteobacteria,46A5K@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Domain of unknown function DUF21	-	-	-	-	-	-	-	-	-	-	-	-	DUF21
k141_3551_2	1519464.HY22_03790	2.23e-59	195.0	COG0151@1|root,COG0151@2|Bacteria	2|Bacteria	F	phosphoribosylamine-glycine ligase activity	purD	-	6.3.4.13,6.3.5.5	ko:K01945,ko:K01955	ko00230,ko00240,ko00250,ko01100,ko01110,ko01130,map00230,map00240,map00250,map01100,map01110,map01130	M00048,M00051	R00256,R00575,R01395,R04144,R10948,R10949	RC00002,RC00010,RC00043,RC00090,RC00166,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_3,GARS_A,GARS_C,GARS_N
k141_9730_1	566466.NOR53_3183	2.56e-53	183.0	COG0477@1|root,COG2814@2|Bacteria,1NU31@1224|Proteobacteria	1224|Proteobacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
k141_7845_1	977880.RALTA_A2830	3.99e-31	126.0	COG1529@1|root,COG1529@2|Bacteria,1MUEA@1224|Proteobacteria,2VJBN@28216|Betaproteobacteria,1KGP4@119060|Burkholderiaceae	28216|Betaproteobacteria	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	1.17.1.4	ko:K00087	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103	RC00143	ko00000,ko00001,ko00002,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
k141_2354_1	314264.ROS217_09045	2.98e-66	218.0	COG2211@1|root,COG2211@2|Bacteria,1MWSH@1224|Proteobacteria,2U0DN@28211|Alphaproteobacteria,46QAF@74030|Roseovarius	28211|Alphaproteobacteria	G	BT1 family	-	-	-	-	-	-	-	-	-	-	-	-	BT1
k141_2972_1	981384.AEYW01000014_gene117	3.78e-77	238.0	COG1176@1|root,COG1176@2|Bacteria,1P34V@1224|Proteobacteria,2U1N8@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	ABC-type spermidine putrescine transport system, permease component I	-	-	-	ko:K11071	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	BPD_transp_1
k141_9072_1	1229909.NSED_00420	5.86e-16	72.4	COG0784@1|root,arCOG02391@2157|Archaea,41T9J@651137|Thaumarchaeota	2157|Archaea	T	COG0784 FOG CheY-like receiver	-	-	-	ko:K02485,ko:K02490,ko:K03413	ko02020,ko02024,ko02030,map02020,map02024,map02030	M00485,M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
k141_9072_2	1229909.NSED_00420	4.8e-19	80.5	COG0784@1|root,arCOG02391@2157|Archaea,41T9J@651137|Thaumarchaeota	2157|Archaea	T	COG0784 FOG CheY-like receiver	-	-	-	ko:K02485,ko:K02490,ko:K03413	ko02020,ko02024,ko02030,map02020,map02024,map02030	M00485,M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
k141_9072_3	1229909.NSED_00415	5.06e-51	165.0	COG4276@1|root,arCOG04604@2157|Archaea,41SI9@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
k141_1737_1	938709.AUSH02000017_gene1026	6.71e-28	115.0	COG4942@1|root,COG4942@2|Bacteria,4NH2T@976|Bacteroidetes	976|Bacteroidetes	D	peptidase M23	envC	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
k141_8479_1	488538.SAR116_0950	2.9e-80	246.0	COG1173@1|root,COG1173@2|Bacteria,1MUG0@1224|Proteobacteria,2TT4V@28211|Alphaproteobacteria,4BPQN@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	EP	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
k141_8479_2	1279015.KB908470_gene256	1.33e-08	55.5	COG1123@1|root,COG4172@2|Bacteria,1MU09@1224|Proteobacteria,1RMEI@1236|Gammaproteobacteria,1Y3KS@135624|Aeromonadales	135624|Aeromonadales	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K02031,ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
k141_1118_1	936455.KI421499_gene4563	1.13e-37	143.0	COG1014@1|root,COG4231@1|root,COG1014@2|Bacteria,COG4231@2|Bacteria,1MUKS@1224|Proteobacteria,2TSHH@28211|Alphaproteobacteria,3JSRZ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	Pyruvate ferredoxin/flavodoxin oxidoreductase	MA20_17555	-	1.2.7.8	ko:K04090	-	-	-	-	br01601,ko00000,ko01000	-	-	-	POR,TPP_enzyme_C
k141_7280_1	318586.Pden_3846	9.87e-96	286.0	COG2801@1|root,COG2801@2|Bacteria,1MVXQ@1224|Proteobacteria,2TU72@28211|Alphaproteobacteria,2PWHY@265|Paracoccus	28211|Alphaproteobacteria	L	Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_21,rve,rve_3
k141_2973_2	762376.AXYL_03217	2.14e-29	116.0	COG3119@1|root,COG3119@2|Bacteria,1MUJH@1224|Proteobacteria,2VNDQ@28216|Betaproteobacteria,3T695@506|Alcaligenaceae	28216|Betaproteobacteria	P	Sulfatase	-	-	3.1.6.1,3.1.6.6	ko:K01130,ko:K01133	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase,Sulfatase_C
k141_9073_1	526222.Desal_2832	4.12e-41	150.0	COG2223@1|root,COG2223@2|Bacteria,1MWC7@1224|Proteobacteria,42P53@68525|delta/epsilon subdivisions,2WJ2U@28221|Deltaproteobacteria,2MAG1@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	Major Facilitator Superfamily	-	-	-	ko:K08177	-	-	-	-	ko00000,ko02000	2.A.1.11	-	-	MFS_1
k141_7281_1	998674.ATTE01000001_gene1384	1.46e-93	293.0	COG0480@1|root,COG0480@2|Bacteria,1MUCV@1224|Proteobacteria,1RNNJ@1236|Gammaproteobacteria,4607G@72273|Thiotrichales	72273|Thiotrichales	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	-	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
k141_6670_1	159749.K0SEJ4	1.49e-35	140.0	COG2801@1|root,KOG0017@2759|Eukaryota,2XHU4@2836|Bacillariophyta	159749.K0SEJ4|-	L	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_1120_1	1121875.KB907555_gene372	1.15e-83	256.0	COG0205@1|root,COG0205@2|Bacteria,4NF8F@976|Bacteroidetes,1HWWG@117743|Flavobacteriia	976|Bacteroidetes	G	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	pfkA	-	2.7.1.11	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	M00001,M00345	R00756,R03236,R03237,R03238,R03239,R04779	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	-	-	-	PFK
k141_4829_1	870187.Thini_1490	6.5e-64	204.0	COG0825@1|root,COG0825@2|Bacteria,1MURN@1224|Proteobacteria,1RNN8@1236|Gammaproteobacteria,4605V@72273|Thiotrichales	72273|Thiotrichales	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA	accA	-	2.1.3.15,6.4.1.2	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	ACCA
k141_5442_2	247634.GPB2148_1067	5.21e-19	85.9	COG0815@1|root,COG0815@2|Bacteria,1MUBU@1224|Proteobacteria,1RM8M@1236|Gammaproteobacteria,1J4WW@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	Transfers the fatty acyl group on membrane lipoproteins	lnt	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016021,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0031224,GO:0031226,GO:0034645,GO:0036211,GO:0042157,GO:0042158,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576	-	ko:K03820	-	-	-	-	ko00000,ko01000	-	GT2	iEcSMS35_1347.EcSMS35_0678,iSbBS512_1146.SbBS512_E0590	CN_hydrolase
k141_1739_1	5297.GMQ_23310T0	2.72e-18	92.0	COG2801@1|root,KOG0017@2759|Eukaryota,38DPC@33154|Opisthokonta,3NUZ7@4751|Fungi,3UY7N@5204|Basidiomycota,2YC45@29000|Pucciniomycotina	4751|Fungi	L	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5314,RVT_2,gag_pre-integrs,rve,zf-CCHC
k141_7359_1	1123514.KB905899_gene1841	7.28e-11	60.5	COG1586@1|root,COG1586@2|Bacteria,1RH88@1224|Proteobacteria,1S7BA@1236|Gammaproteobacteria,4619B@72273|Thiotrichales	72273|Thiotrichales	E	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine	speH	-	4.1.1.50	ko:K01611	ko00270,ko00330,ko01100,map00270,map00330,map01100	M00034,M00133	R00178	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	AdoMet_dc
k141_7359_2	1207063.P24_05772	3.16e-63	202.0	COG0421@1|root,COG0421@2|Bacteria,1MVV5@1224|Proteobacteria,2TQZ3@28211|Alphaproteobacteria,2JRG9@204441|Rhodospirillales	204441|Rhodospirillales	E	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	speE	-	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	Spermine_synt_N,Spermine_synth
k141_3640_1	159749.E7BWP5	3.04e-136	396.0	COG0050@1|root,KOG0460@2759|Eukaryota,2XBKK@2836|Bacillariophyta	2759|Eukaryota	J	Elongation factor Tu	tufA	GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005634,GO:0005730,GO:0005737,GO:0009295,GO:0009507,GO:0009526,GO:0009532,GO:0009534,GO:0009535,GO:0009536,GO:0009570,GO:0009579,GO:0009941,GO:0016020,GO:0020011,GO:0031967,GO:0031974,GO:0031975,GO:0031976,GO:0031981,GO:0031984,GO:0034357,GO:0042651,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044422,GO:0044424,GO:0044428,GO:0044434,GO:0044435,GO:0044436,GO:0044444,GO:0044446,GO:0044464,GO:0048046,GO:0055035,GO:0070013	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
k141_6754_1	45157.CMW010CT	2.31e-60	195.0	COG1622@1|root,KOG4767@2759|Eukaryota	2759|Eukaryota	C	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor	COX2	GO:0003674,GO:0003824,GO:0004129,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005746,GO:0005751,GO:0006091,GO:0006119,GO:0006123,GO:0006139,GO:0006140,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0006950,GO:0006979,GO:0007275,GO:0007589,GO:0007595,GO:0008150,GO:0008152,GO:0008324,GO:0009055,GO:0009060,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009266,GO:0009409,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010310,GO:0010562,GO:0010726,GO:0010728,GO:0010729,GO:0010939,GO:0010940,GO:0010941,GO:0010942,GO:0015002,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015672,GO:0015980,GO:0016020,GO:0016021,GO:0016310,GO:0016491,GO:0016675,GO:0016676,GO:0017144,GO:0019219,GO:0019220,GO:0019222,GO:0019637,GO:0019646,GO:0019693,GO:0019866,GO:0022857,GO:0022890,GO:0022900,GO:0022904,GO:0030808,GO:0030810,GO:0030879,GO:0031090,GO:0031224,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031966,GO:0031967,GO:0031975,GO:0032501,GO:0032502,GO:0032991,GO:0034220,GO:0034641,GO:0042773,GO:0042775,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044281,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044444,GO:0044446,GO:0044455,GO:0044464,GO:0045277,GO:0045333,GO:0045935,GO:0045937,GO:0045981,GO:0046034,GO:0046483,GO:0046903,GO:0048513,GO:0048518,GO:0048522,GO:0048731,GO:0048732,GO:0048856,GO:0050789,GO:0050794,GO:0050878,GO:0050896,GO:0051171,GO:0051173,GO:0051174,GO:0051179,GO:0051193,GO:0051194,GO:0051234,GO:0055085,GO:0055086,GO:0055114,GO:0062012,GO:0062013,GO:0065007,GO:0065008,GO:0070069,GO:0070469,GO:0071704,GO:0072521,GO:0080090,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098798,GO:0098800,GO:0098803,GO:1900371,GO:1900373,GO:1900542,GO:1900544,GO:1901135,GO:1901360,GO:1901564,GO:1902600,GO:1903426,GO:1903428,GO:1903578,GO:1903580,GO:2000377,GO:2000379,GO:2001169,GO:2001171	1.9.3.1	ko:K02256,ko:K02261	ko00190,ko01100,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map04260,map04714,map04932,map05010,map05012,map05016	M00154	-	-	ko00000,ko00001,ko00002,ko01000,ko03029	3.D.4.11,3.D.4.7,3.D.4.8	-	-	COX2,COX2_TM
k141_3061_1	270374.MELB17_05067	1.29e-79	256.0	COG4176@1|root,COG4176@2|Bacteria,1MUM4@1224|Proteobacteria,1SK88@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02001	ko02010,map02010	M00208	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	BPD_transp_1
k141_7931_1	95619.PM1_0201590	2.56e-75	238.0	COG1804@1|root,COG1804@2|Bacteria,1MU2K@1224|Proteobacteria,1RNB5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	acyl-CoA transferases carnitine dehydratase	coaT	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
k141_7361_1	583355.Caka_1337	2.26e-65	215.0	COG0187@1|root,COG0187@2|Bacteria,46SEN@74201|Verrucomicrobia,3K7SG@414999|Opitutae	414999|Opitutae	L	DNA topoisomerase type IIA subunit B region 2 domain protein	-	-	-	ko:K02622	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_gyraseB,HATPase_c,Toprim
k141_4907_1	1121935.AQXX01000122_gene5677	1.16e-48	170.0	28KPT@1|root,2ZA7X@2|Bacteria,1MXE6@1224|Proteobacteria,1RYVK@1236|Gammaproteobacteria,1XP1G@135619|Oceanospirillales	135619|Oceanospirillales	S	COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_7932_1	414684.RC1_3366	7e-62	201.0	COG0444@1|root,COG0444@2|Bacteria,1R4KB@1224|Proteobacteria,2TR0J@28211|Alphaproteobacteria,2JPT1@204441|Rhodospirillales	204441|Rhodospirillales	EP	Oligopeptide/dipeptide transporter, C-terminal region	-	-	-	ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
k141_6709_1	998674.ATTE01000001_gene478	3.15e-57	189.0	COG1181@1|root,COG1181@2|Bacteria,1MUTB@1224|Proteobacteria,1RMTM@1236|Gammaproteobacteria,4606P@72273|Thiotrichales	72273|Thiotrichales	F	Belongs to the D-alanine--D-alanine ligase family	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
k141_3016_1	751994.AGIG01000007_gene1242	8.12e-65	209.0	COG1744@1|root,COG1744@2|Bacteria,1MWTM@1224|Proteobacteria,1RYCX@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	ABC-type transport system, periplasmic component surface lipoprotein	-	-	-	ko:K02058	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	Bmp
k141_1777_1	1122135.KB893157_gene424	1.19e-27	111.0	COG0583@1|root,COG0583@2|Bacteria,1N178@1224|Proteobacteria,2TS42@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	Transcriptional regulator, LysR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
k141_1777_2	472175.EL18_00430	1.64e-53	174.0	COG0479@1|root,COG0479@2|Bacteria,1MVHS@1224|Proteobacteria,2U08R@28211|Alphaproteobacteria,43P35@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	C	2Fe-2S iron-sulfur cluster binding domain	frdB	-	1.3.5.4	ko:K00245	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	M00009,M00011,M00150,M00173	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_3,Fer4_17,Fer4_8
k141_8525_1	1484460.JSWG01000004_gene2630	5.75e-31	119.0	COG3743@1|root,COG5557@1|root,COG3743@2|Bacteria,COG5557@2|Bacteria,4NE3X@976|Bacteroidetes,1HY9P@117743|Flavobacteriia	976|Bacteroidetes	C	Polysulphide reductase	nrfD	-	-	ko:K00185	-	-	-	-	ko00000	5.A.3	-	-	NrfD
k141_8525_2	1123037.AUDE01000013_gene577	7.43e-80	239.0	COG2010@1|root,COG2010@2|Bacteria,4NEX9@976|Bacteroidetes,1HXN6@117743|Flavobacteriia	976|Bacteroidetes	C	membrane	actD	-	-	-	-	-	-	-	-	-	-	-	DUF3341
k141_3657_1	1305735.JAFT01000005_gene354	1.47e-06	50.4	COG0501@1|root,COG0501@2|Bacteria,1NK9F@1224|Proteobacteria,2UQWK@28211|Alphaproteobacteria,2PDVI@252301|Oceanicola	28211|Alphaproteobacteria	O	Peptidase family M48	-	-	-	ko:K07387	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M48
k141_3657_2	1224746.B932_3778	3.69e-31	115.0	COG3293@1|root,COG3293@2|Bacteria,1RAR8@1224|Proteobacteria,2U5DG@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	Putative transposase of IS4/5 family (DUF4096)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4096
k141_3657_3	366394.Smed_6151	3.73e-07	53.5	COG3293@1|root,COG3293@2|Bacteria,1P5HD@1224|Proteobacteria,2U54G@28211|Alphaproteobacteria,4BG4F@82115|Rhizobiaceae	28211|Alphaproteobacteria	L	Putative transposase of IS4/5 family (DUF4096)	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_2,DUF4096
k141_1215_1	396588.Tgr7_0841	2.82e-23	102.0	COG1066@1|root,COG1066@2|Bacteria,1MUJQ@1224|Proteobacteria,1RN2E@1236|Gammaproteobacteria,1WWW0@135613|Chromatiales	135613|Chromatiales	O	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function	radA	-	-	ko:K04485	-	-	-	-	ko00000,ko03400	-	-	-	AAA_25,ATPase,ChlI,Lon_C
k141_6776_1	886377.Murru_1577	9.89e-26	104.0	COG0750@1|root,COG0750@2|Bacteria,4NEAR@976|Bacteroidetes,1HXEV@117743|Flavobacteriia	976|Bacteroidetes	M	zinc metalloprotease	rseP	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_M50
k141_6776_2	616991.JPOO01000001_gene2750	5.71e-23	94.0	COG1999@1|root,COG1999@2|Bacteria,4NFH2@976|Bacteroidetes,1HXP2@117743|Flavobacteriia,23FTZ@178469|Arenibacter	976|Bacteroidetes	S	SCO1/SenC	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC
k141_4308_1	1120999.JONM01000002_gene951	2.1e-75	233.0	COG0204@1|root,COG0204@2|Bacteria	2|Bacteria	I	Acyl-transferase	cmk	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase,Cytidylate_kin
k141_2464_1	1349785.BAUG01000023_gene1500	3.1e-79	252.0	COG2759@1|root,COG2759@2|Bacteria,4NG3E@976|Bacteroidetes,1HXR5@117743|Flavobacteriia	976|Bacteroidetes	H	Belongs to the formate--tetrahydrofolate ligase family	fhs	GO:0003674,GO:0003824,GO:0004329,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006144,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009112,GO:0009113,GO:0009256,GO:0009257,GO:0009396,GO:0009987,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0016874,GO:0016879,GO:0018130,GO:0019238,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042440,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046112,GO:0046148,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.4.3	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R00943	RC00026,RC00111	ko00000,ko00001,ko00002,ko01000	-	-	-	FTHFS
k141_9828_1	391937.NA2_20891	1.75e-44	157.0	COG4608@1|root,COG4608@2|Bacteria,1NU4K@1224|Proteobacteria,2TQTV@28211|Alphaproteobacteria,43HDX@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	E	Oligopeptide/dipeptide transporter, C-terminal region	MA20_16745	-	-	ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
k141_1216_1	391624.OIHEL45_10538	8.25e-12	66.2	COG0518@1|root,COG0518@2|Bacteria,1MV9U@1224|Proteobacteria,2TUIN@28211|Alphaproteobacteria	28211|Alphaproteobacteria	F	glutamine amidotransferase	-	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase
k141_3080_1	159749.K0T6C5	3.25e-51	184.0	COG2801@1|root,KOG0017@2759|Eukaryota,2XF4I@2836|Bacillariophyta	159749.K0T6C5|-	L	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_7951_1	159749.K0SXC9	6.04e-57	200.0	29N4Q@1|root,2RVF7@2759|Eukaryota,2XBJX@2836|Bacillariophyta	159749.K0SXC9|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_1217_1	296591.Bpro_1241	3.82e-17	76.6	COG0219@1|root,COG0219@2|Bacteria,1RCY4@1224|Proteobacteria,2VR5W@28216|Betaproteobacteria,4ADKI@80864|Comamonadaceae	28216|Betaproteobacteria	J	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide	trmL	-	2.1.1.207	ko:K03216	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
k141_609_2	391626.OAN307_c30700	9.59e-205	577.0	COG3328@1|root,COG3328@2|Bacteria,1MU4P@1224|Proteobacteria,2TTAW@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_mut
k141_4923_1	1120951.AUBG01000027_gene1834	0.000338	39.3	2EHTW@1|root,33BJI@2|Bacteria,4NVVE@976|Bacteroidetes,1I62I@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_4923_2	980584.AFPB01000023_gene929	2.08e-63	194.0	2B9ZZ@1|root,323DM@2|Bacteria,4NTEB@976|Bacteroidetes,1I2YU@117743|Flavobacteriia	976|Bacteroidetes	S	COG NOG15344 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_4923_3	1123234.AUKI01000010_gene1721	1.11e-99	290.0	2AU0F@1|root,31JKB@2|Bacteria,4NHS6@976|Bacteroidetes,1I02M@117743|Flavobacteriia	976|Bacteroidetes	S	COG NOG14600 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_3659_1	1304885.AUEY01000005_gene800	1.68e-156	456.0	COG1960@1|root,COG1960@2|Bacteria,1R15B@1224|Proteobacteria,42MUT@68525|delta/epsilon subdivisions,2WJ8T@28221|Deltaproteobacteria,2MI3E@213118|Desulfobacterales	28221|Deltaproteobacteria	C	acyl-CoA dehydrogenase	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1
k141_7952_1	1229909.NSED_01465	7.44e-103	306.0	COG0598@1|root,arCOG02265@2157|Archaea,41SZC@651137|Thaumarchaeota	651137|Thaumarchaeota	P	Mg2 transporter protein	-	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
k141_3082_1	1220601.L7TJ79_9CAUD	3.77e-56	191.0	4QCM5@10239|Viruses,4QVZY@35237|dsDNA viruses  no RNA stage,4QQFH@28883|Caudovirales	28883|Caudovirales	S	Bacteriophage head to tail connecting protein	-	GO:0005575,GO:0008150,GO:0016032,GO:0019012,GO:0019028,GO:0019058,GO:0019068,GO:0019072,GO:0019073,GO:0032991,GO:0044403,GO:0044419,GO:0044423,GO:0046798,GO:0051704	-	-	-	-	-	-	-	-	-	-	-
k141_4310_1	1380391.JIAS01000018_gene838	2.09e-147	429.0	COG4671@1|root,COG4671@2|Bacteria,1N1PQ@1224|Proteobacteria,2TSTV@28211|Alphaproteobacteria,2JRG0@204441|Rhodospirillales	204441|Rhodospirillales	S	Glycosyltransferase family 28 C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tran_28_C
k141_7387_1	941639.BCO26_0066	1.31e-07	50.1	2DMNG@1|root,32SP1@2|Bacteria,1VAXC@1239|Firmicutes,4HM1Q@91061|Bacilli,1ZI92@1386|Bacillus	91061|Bacilli	S	COG NOG14552 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_610_1	580332.Slit_2551	1.48e-61	202.0	COG1156@1|root,COG1156@2|Bacteria,1QUQE@1224|Proteobacteria	1224|Proteobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit	-	-	-	ko:K02118	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_ab
k141_610_2	323261.Noc_2083	3.05e-42	155.0	COG1155@1|root,COG1155@2|Bacteria,1MWRR@1224|Proteobacteria,1RSFG@1236|Gammaproteobacteria,1WW9R@135613|Chromatiales	135613|Chromatiales	F	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit	-	-	3.6.3.14,3.6.3.15	ko:K02117	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002,ko01000	3.A.2.2,3.A.2.3	-	-	ATP-synt_ab,ATP-synt_ab_N,ATP-synt_ab_Xtn
k141_6778_1	1111732.AZOD01000055_gene246	1.57e-23	90.9	2EG3W@1|root,339VW@2|Bacteria,1NHIR@1224|Proteobacteria,1SGXB@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_7954_1	983917.RGE_34690	1.99e-18	88.2	COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,1MUKF@1224|Proteobacteria,2VHKP@28216|Betaproteobacteria,1KKBX@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	DNA internalization-related competence protein ComEC Rec2	comA	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131,Lactamase_B
k141_4927_1	1298593.TOL_0315	1e-05	50.1	COG1416@1|root,COG1416@2|Bacteria,1NAV2@1224|Proteobacteria,1SYA3@1236|Gammaproteobacteria,1XM9S@135619|Oceanospirillales	135619|Oceanospirillales	-	-	-	-	-	ko:K09004	-	-	-	-	ko00000	-	-	-	DrsE
k141_6779_1	331678.Cphamn1_2437	2.13e-28	115.0	COG5433@1|root,COG5433@2|Bacteria	2|Bacteria	L	transposase activity	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_4
k141_611_1	159749.K0TP24	4.23e-74	253.0	COG2801@1|root,2QT1S@2759|Eukaryota	2759|Eukaryota	L	transposition	-	-	-	-	-	-	-	-	-	-	-	-	RVT_1,rve
k141_7955_1	89187.ISM_08455	2.66e-58	199.0	COG0443@1|root,COG0443@2|Bacteria,1MVEN@1224|Proteobacteria,2TR5H@28211|Alphaproteobacteria,46NTJ@74030|Roseovarius	28211|Alphaproteobacteria	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
k141_8595_1	314270.RB2083_958	3.33e-91	283.0	COG0459@1|root,COG0459@2|Bacteria,1MURR@1224|Proteobacteria,2TS07@28211|Alphaproteobacteria,3ZGER@58840|unclassified Rhodobacteraceae	28211|Alphaproteobacteria	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
k141_6162_1	1123269.NX02_25820	1.16e-13	72.0	COG4246@1|root,COG4246@2|Bacteria,1N7Y1@1224|Proteobacteria,2TTZW@28211|Alphaproteobacteria,2K10G@204457|Sphingomonadales	204457|Sphingomonadales	S	Esterase-like activity of phytase	-	-	-	-	-	-	-	-	-	-	-	-	Phytase-like
k141_6162_2	1117943.SFHH103_03462	1.5e-61	204.0	COG3385@1|root,COG3385@2|Bacteria,1R821@1224|Proteobacteria,2VG9M@28211|Alphaproteobacteria,4BIX9@82115|Rhizobiaceae	28211|Alphaproteobacteria	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
k141_4928_1	1158292.JPOE01000002_gene1668	3.98e-105	315.0	COG1850@1|root,COG1850@2|Bacteria,1MWEB@1224|Proteobacteria,2VJF4@28216|Betaproteobacteria,1KJRD@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site	cbbL	-	4.1.1.39	ko:K01601	ko00630,ko00710,ko01100,ko01120,ko01200,map00630,map00710,map01100,map01120,map01200	M00165,M00166,M00532	R00024,R03140	RC00172,RC00859	ko00000,ko00001,ko00002,ko01000	-	-	-	RuBisCO_large,RuBisCO_large_N
k141_9191_1	35128.Thapsdraft2063	4.01e-40	147.0	COG3854@1|root,2QQ4X@2759|Eukaryota,2XEFS@2836|Bacillariophyta	2836|Bacillariophyta	L	AAA domain	ycf45	-	-	-	-	-	-	-	-	-	-	-	-
k141_9191_2	395961.Cyan7425_4504	6.65e-17	75.1	COG0236@1|root,COG0236@2|Bacteria,1G9GC@1117|Cyanobacteria,3KIPJ@43988|Cyanothece	1117|Cyanobacteria	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
k141_6163_1	765914.ThisiDRAFT_0009	1.82e-91	293.0	COG0525@1|root,COG0525@2|Bacteria,1MV7B@1224|Proteobacteria,1RNEB@1236|Gammaproteobacteria,1WWJI@135613|Chromatiales	135613|Chromatiales	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	-	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
k141_9192_1	1403819.BATR01000098_gene3230	4.53e-59	199.0	COG0119@1|root,COG0119@2|Bacteria,46S6Z@74201|Verrucomicrobia,2ITQ0@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	LeuA allosteric (dimerisation) domain	-	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
k141_6781_1	159749.K0RB93	2.95e-29	110.0	COG2421@1|root,2QRMK@2759|Eukaryota,2XFTY@2836|Bacillariophyta	2836|Bacillariophyta	E	Acetamidase/Formamidase family	-	-	3.5.1.49	ko:K01455	ko00460,ko00630,ko00910,ko01200,map00460,map00630,map00910,map01200	-	R00524	RC02432,RC02810	ko00000,ko00001,ko01000	-	-	-	FmdA_AmdA
k141_4930_1	1231190.NA8A_19333	3.09e-110	335.0	COG0465@1|root,COG0465@2|Bacteria,1MU6J@1224|Proteobacteria,2TRNK@28211|Alphaproteobacteria,43GXZ@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	-	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
k141_7392_1	1380394.JADL01000011_gene3932	7.06e-64	206.0	COG0075@1|root,COG0075@2|Bacteria,1MWHJ@1224|Proteobacteria,2TQSN@28211|Alphaproteobacteria,2JRM8@204441|Rhodospirillales	204441|Rhodospirillales	E	Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily	phnW	-	2.6.1.37	ko:K03430	ko00440,ko01100,ko01120,map00440,map01100,map01120	-	R04152	RC00008,RC00062	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_5
k141_7392_2	6500.XP_005099940.1	5.84e-25	100.0	COG0637@1|root,2QU58@2759|Eukaryota,39WII@33154|Opisthokonta,3BF9K@33208|Metazoa,3D4RC@33213|Bilateria	33208|Metazoa	S	Haloacid dehalogenase-like hydrolase	-	-	3.11.1.1	ko:K05306	ko00440,ko01100,ko01120,map00440,map01100,map01120	-	R00747	RC00368	ko00000,ko00001,ko01000	-	-	-	HAD_2
k141_1224_1	686340.Metal_0379	1.25e-37	129.0	COG0102@1|root,COG0102@2|Bacteria,1RA11@1224|Proteobacteria,1S280@1236|Gammaproteobacteria,1XF2I@135618|Methylococcales	135618|Methylococcales	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rplM	-	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
k141_1224_2	28229.ND2E_1081	2.52e-55	175.0	COG0103@1|root,COG0103@2|Bacteria,1RD4A@1224|Proteobacteria,1S3Q7@1236|Gammaproteobacteria,2Q6XI@267889|Colwelliaceae	1236|Gammaproteobacteria	J	Belongs to the universal ribosomal protein uS9 family	rpsI	GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
k141_4931_1	1458357.BG58_18545	7.3e-12	71.6	COG3210@1|root,COG3210@2|Bacteria,1MXIP@1224|Proteobacteria,2VJ6Y@28216|Betaproteobacteria,1K3NJ@119060|Burkholderiaceae	28216|Betaproteobacteria	U	family outer membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	ESPR,Haemagg_act
k141_7393_1	1288494.EBAPG3_450	2.39e-142	412.0	COG1850@1|root,COG1850@2|Bacteria,1MWEB@1224|Proteobacteria,2VJF4@28216|Betaproteobacteria,371TS@32003|Nitrosomonadales	28216|Betaproteobacteria	H	RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site	cbbL	-	4.1.1.39	ko:K01601	ko00630,ko00710,ko01100,ko01120,ko01200,map00630,map00710,map01100,map01120,map01200	M00165,M00166,M00532	R00024,R03140	RC00172,RC00859	ko00000,ko00001,ko00002,ko01000	-	-	-	RuBisCO_large,RuBisCO_large_N
k141_9837_1	1250232.JQNJ01000001_gene1739	2.19e-18	89.4	COG1361@1|root,COG3209@1|root,COG1361@2|Bacteria,COG3209@2|Bacteria,4PKBQ@976|Bacteroidetes	976|Bacteroidetes	M	SPTR CHU large protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,DUF11,SprB
k141_7394_2	1121022.ABENE_21950	1.06e-15	76.3	COG3547@1|root,COG3547@2|Bacteria,1MUER@1224|Proteobacteria,2TSGZ@28211|Alphaproteobacteria,2KHQT@204458|Caulobacterales	204458|Caulobacterales	L	PFAM transposase IS116 IS110 IS902 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k141_1226_1	1408287.AXUR01000160_gene210	3.52e-65	205.0	COG0687@1|root,COG0687@2|Bacteria	2|Bacteria	E	Required for the activity of the bacterial periplasmic transport system of putrescine	potD	-	-	ko:K02055	ko02024,map02024	M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11	-	-	SBP_bac_8
k141_616_1	1229909.NSED_02750	6.19e-145	419.0	COG0422@1|root,arCOG02741@2157|Archaea,41S5Z@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Thiamine biosynthesis protein ThiC	-	-	4.1.99.17	ko:K03147	ko00730,ko01100,map00730,map01100	M00127	R03472	RC03251,RC03252	ko00000,ko00001,ko00002,ko01000	-	-	-	ThiC_Rad_SAM
k141_4933_1	1122614.JHZF01000013_gene3063	1.43e-22	102.0	COG2373@1|root,COG2373@2|Bacteria,1MV7J@1224|Proteobacteria,2TSAE@28211|Alphaproteobacteria,2PCME@252301|Oceanicola	28211|Alphaproteobacteria	S	Alpha-2-Macroglobulin	MA20_30110	-	-	ko:K06894	-	-	-	-	ko00000	-	-	-	A2M,A2M_N,A2M_N_2,MG1,PAN_1,Thiol-ester_cl
k141_9196_1	1121403.AUCV01000056_gene3021	1.9e-24	103.0	COG0330@1|root,COG0330@2|Bacteria,1MUM2@1224|Proteobacteria,42NUT@68525|delta/epsilon subdivisions,2WKQX@28221|Deltaproteobacteria,2MI5I@213118|Desulfobacterales	28221|Deltaproteobacteria	O	HflC and HflK could encode or regulate a protease	hflK	-	-	ko:K04088	-	M00742	-	-	ko00000,ko00002,ko01000	-	-	-	Band_7
k141_7833_2	765913.ThidrDRAFT_2344	6.67e-24	99.0	COG2175@1|root,COG2175@2|Bacteria,1R5KS@1224|Proteobacteria,1RZQ2@1236|Gammaproteobacteria,1WXSM@135613|Chromatiales	135613|Chromatiales	Q	Taurine catabolism dioxygenase TauD, TfdA family	-	-	-	-	-	-	-	-	-	-	-	-	TauD
k141_2343_1	467661.RKLH11_3232	1.8e-28	110.0	COG1834@1|root,COG1834@2|Bacteria,1R5UT@1224|Proteobacteria,2U4VJ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	N-dimethylarginine dimethylaminohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidinotransf
k141_2343_2	357804.Ping_2544	5e-30	112.0	COG0500@1|root,COG2226@2|Bacteria,1N0SX@1224|Proteobacteria	1224|Proteobacteria	Q	PFAM Methyltransferase type	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25,Methyltransf_31
k141_6032_1	626887.J057_22515	2.68e-06	50.8	COG3147@1|root,COG3147@2|Bacteria,1NGE3@1224|Proteobacteria,1SCGC@1236|Gammaproteobacteria,468K7@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	protein conserved in bacteria	dedD	-	-	ko:K03749	-	-	-	-	ko00000	-	-	-	SPOR
k141_6032_2	925775.XVE_3022	4.45e-07	52.8	COG0285@1|root,COG0285@2|Bacteria,1MVCH@1224|Proteobacteria,1RMB0@1236|Gammaproteobacteria,1X32Z@135614|Xanthomonadales	135614|Xanthomonadales	H	Belongs to the folylpolyglutamate synthase family	folC	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_C,Mur_ligase_M
k141_4199_1	323261.Noc_0962	1.92e-55	182.0	COG0123@1|root,COG0123@2|Bacteria,1MU7P@1224|Proteobacteria,1RN8W@1236|Gammaproteobacteria,1WZ4R@135613|Chromatiales	135613|Chromatiales	BQ	PFAM histone deacetylase superfamily	-	-	-	ko:K04768	-	-	-	-	ko00000	-	-	-	Hist_deacetyl
k141_6658_1	314285.KT71_02987	2.43e-26	108.0	COG0596@1|root,COG0596@2|Bacteria,1QIT9@1224|Proteobacteria,1SMU1@1236|Gammaproteobacteria,1J9QV@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
k141_9719_1	314264.ROS217_00075	2.45e-113	337.0	COG3666@1|root,COG3666@2|Bacteria,1QW5T@1224|Proteobacteria,2TWNW@28211|Alphaproteobacteria,46RGF@74030|Roseovarius	28211|Alphaproteobacteria	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_6,DUF772
k141_4200_1	570967.JMLV01000001_gene2477	1.64e-127	369.0	COG0568@1|root,COG0568@2|Bacteria,1MVWR@1224|Proteobacteria,2TR9Q@28211|Alphaproteobacteria,2JPF6@204441|Rhodospirillales	204441|Rhodospirillales	K	RNA polymerase sigma	rpoH	-	-	ko:K03089	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r4
k141_5429_1	1524880.A0A076G6J2_9VIRU	1.09e-26	110.0	4QD9Y@10239|Viruses	10239|Viruses	S	Pfam:Terminase_6C	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_7834_1	35128.Thapsdraft2088	4.75e-197	555.0	COG1850@1|root,2QTI9@2759|Eukaryota,2XE5R@2836|Bacillariophyta	2836|Bacillariophyta	Q	RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process. Both reactions occur simultaneously and in competition at the same active site	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009536,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464	4.1.1.39	ko:K01601	ko00630,ko00710,ko01100,ko01120,ko01200,map00630,map00710,map01100,map01120,map01200	M00165,M00166,M00532	R00024,R03140	RC00172,RC00859	ko00000,ko00001,ko00002,ko01000	-	-	-	RuBisCO_large,RuBisCO_large_N
k141_4818_1	314285.KT71_16086	1.84e-64	208.0	COG0583@1|root,COG0583@2|Bacteria,1MU8N@1224|Proteobacteria,1RN7T@1236|Gammaproteobacteria,1J4E3@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	K	Transcriptional regulator	cysB	GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009314,GO:0009628,GO:0010165,GO:0010212,GO:0042802,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0097159,GO:1901363	-	ko:K13634	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,LysR_substrate
k141_9721_1	1121104.AQXH01000001_gene2087	2.4e-42	155.0	COG2987@1|root,COG2987@2|Bacteria,4NF2P@976|Bacteroidetes	976|Bacteroidetes	E	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate	hutU	-	4.2.1.49	ko:K01712	ko00340,ko01100,map00340,map01100	M00045	R02914	RC00804	ko00000,ko00001,ko00002,ko01000	-	-	-	Urocanase,Urocanase_C,Urocanase_N
k141_2345_1	35128.Thapsdraft1545	2.35e-176	500.0	28ISP@1|root,2QR3X@2759|Eukaryota,2XE5P@2836|Bacillariophyta	2836|Bacillariophyta	P	One of the components of the core complex of photosystem II (PSII). It binds chlorophyll and helps catalyze the primary light-induced photochemical processes of PSII. PSII is a light- driven water plastoquinone oxidoreductase, using light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation	-	-	-	ko:K02705	ko00195,ko01100,map00195,map01100	M00161	-	-	ko00000,ko00001,ko00002,ko00194	-	-	-	PSII
k141_9066_1	1415778.JQMM01000001_gene1749	1.06e-112	344.0	COG0542@1|root,COG0542@2|Bacteria,1MV8B@1224|Proteobacteria,1RMH3@1236|Gammaproteobacteria,1J5A1@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	O	Belongs to the ClpA ClpB family	clpA	GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0043335,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564	-	ko:K03694	-	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
k141_1729_2	1229172.JQFA01000002_gene3290	1.6e-11	66.2	COG0520@1|root,COG0520@2|Bacteria,1G30B@1117|Cyanobacteria,1H8VP@1150|Oscillatoriales	1117|Cyanobacteria	E	PFAM Aminotransferase class-V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
k141_4201_1	665029.EAMY_0761	1.31e-13	75.1	COG0585@1|root,COG0585@2|Bacteria,1MXHD@1224|Proteobacteria,1RPRF@1236|Gammaproteobacteria,3X5ZC@551|Erwinia	1236|Gammaproteobacteria	J	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs	truD	GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0016070,GO:0016853,GO:0016866,GO:0034641,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360	5.4.99.27	ko:K06176	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruD
k141_3543_1	425104.Ssed_3707	2.73e-105	316.0	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,1RM93@1236|Gammaproteobacteria,2QB7U@267890|Shewanellaceae	1236|Gammaproteobacteria	I	Belongs to the thiolase family	pcaF	-	2.3.1.16,2.3.1.9	ko:K00626,ko:K00632	ko00071,ko00072,ko00280,ko00281,ko00310,ko00362,ko00380,ko00592,ko00620,ko00630,ko00640,ko00642,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00281,map00310,map00362,map00380,map00592,map00620,map00630,map00640,map00642,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00087,M00088,M00095,M00113,M00373,M00374,M00375	R00238,R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
k141_1731_1	1089439.KB902270_gene2517	4.01e-111	327.0	COG0191@1|root,COG0191@2|Bacteria,1MURX@1224|Proteobacteria,1RQUC@1236|Gammaproteobacteria,45ZXX@72273|Thiotrichales	72273|Thiotrichales	G	Fructose-bisphosphate aldolase, class II, Calvin cycle subtype	-	-	4.1.2.13	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167,M00344,M00345	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	F_bP_aldolase
k141_9723_1	1298593.TOL_3456	8.72e-77	256.0	COG0086@1|root,COG0086@2|Bacteria,1MU3M@1224|Proteobacteria,1RPYH@1236|Gammaproteobacteria,1XH56@135619|Oceanospirillales	135619|Oceanospirillales	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	-	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
k141_5431_1	1095769.CAHF01000011_gene2491	9.74e-69	230.0	COG1009@1|root,COG1009@2|Bacteria,1MW2M@1224|Proteobacteria,2VJ2J@28216|Betaproteobacteria,472FQ@75682|Oxalobacteraceae	28216|Betaproteobacteria	CP	NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus	nuoL	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_C,Proton_antipo_M,Proton_antipo_N
k141_1109_1	639282.DEFDS_0262	1.09e-37	148.0	COG0664@1|root,COG0668@1|root,COG0664@2|Bacteria,COG0668@2|Bacteria	2|Bacteria	M	transmembrane transport	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel,cNMP_binding
k141_496_1	1040989.AWZU01000031_gene3919	1.24e-55	176.0	COG3415@1|root,COG3415@2|Bacteria,1RJ69@1224|Proteobacteria,2UB2N@28211|Alphaproteobacteria,3JYIE@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	L	Transposase	-	-	-	ko:K07499	-	-	-	-	ko00000	-	-	-	HTH_23,HTH_32,HTH_Tnp_IS630,PAX
k141_7886_1	323848.Nmul_A1556	3.65e-09	63.2	COG0642@1|root,COG0784@1|root,COG2198@1|root,COG5002@1|root,COG0784@2|Bacteria,COG2198@2|Bacteria,COG2205@2|Bacteria,COG5002@2|Bacteria,1NRP8@1224|Proteobacteria,2VGZQ@28216|Betaproteobacteria,374RC@32003|Nitrosomonadales	28216|Betaproteobacteria	T	Histidine Phosphotransfer domain	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,HAMP,HATPase_c,HisKA,Hpt,MHYT,PAS,PAS_3,PAS_4,PAS_9,Response_reg,dCache_1
k141_1778_1	1229909.NSED_08925	5.74e-108	326.0	arCOG08793@1|root,arCOG08812@1|root,arCOG08793@2157|Archaea,arCOG08812@2157|Archaea,41SXB@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_5482_1	2850.Phatr40612	9.38e-59	208.0	2D25Z@1|root,2SKKF@2759|Eukaryota,2XEGK@2836|Bacillariophyta	2836|Bacillariophyta	-	-	-	-	-	-	-	-	-	-	-	-	-	-	rve
k141_6094_1	391626.OAN307_c18850	1.13e-12	65.1	COG4681@1|root,COG4681@2|Bacteria,1RDR9@1224|Proteobacteria,2TU26@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	YaeQ
k141_547_1	1049564.TevJSym_ab01480	6.24e-119	351.0	COG0112@1|root,COG0112@2|Bacteria,1MUIS@1224|Proteobacteria,1RMHQ@1236|Gammaproteobacteria,1J4EX@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
k141_547_2	502025.Hoch_1780	3.79e-07	51.2	COG0855@1|root,COG0855@2|Bacteria,1MUM3@1224|Proteobacteria,42NN7@68525|delta/epsilon subdivisions,2WJG7@28221|Deltaproteobacteria,2YUAP@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
k141_7316_1	272943.RSP_0366	1.65e-95	290.0	COG0104@1|root,COG0104@2|Bacteria,1MU5B@1224|Proteobacteria,2TRKY@28211|Alphaproteobacteria,1FAUW@1060|Rhodobacter	28211|Alphaproteobacteria	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
k141_7887_1	247639.MGP2080_12272	2.3e-47	167.0	COG4658@1|root,COG4658@2|Bacteria,1MVY6@1224|Proteobacteria,1T20Y@1236|Gammaproteobacteria,1JC0A@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol	nqrB	-	1.6.5.8	ko:K00347,ko:K03614	-	-	-	-	ko00000,ko01000	-	-	-	NQR2_RnfD_RnfE
k141_8527_1	1304885.AUEY01000050_gene1206	2.38e-56	193.0	COG0151@1|root,COG0151@2|Bacteria,1MUAH@1224|Proteobacteria,42MCI@68525|delta/epsilon subdivisions,2WJ7H@28221|Deltaproteobacteria,2MIPF@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC,GARS_A,GARS_C,GARS_N
k141_5484_1	1237149.C900_02181	1.75e-64	210.0	COG2204@1|root,COG2204@2|Bacteria,4NE72@976|Bacteroidetes,47KVF@768503|Cytophagia	976|Bacteroidetes	T	CheY-like receiver AAA-type ATPase and DNA-binding domains	porX	-	-	-	-	-	-	-	-	-	-	-	PglZ,Response_reg
k141_9118_1	1320556.AVBP01000020_gene239	1.48e-91	278.0	COG4948@1|root,COG4948@2|Bacteria,1MYZE@1224|Proteobacteria,2TU3A@28211|Alphaproteobacteria,43PSR@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	M	Mandelate racemase / muconate lactonizing enzyme, C-terminal domain	-	-	4.2.1.156,4.2.1.42	ko:K20023	ko00053,map00053	-	R05608	RC00543	ko00000,ko00001,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
k141_2401_1	1283300.ATXB01000001_gene679	1.09e-51	182.0	COG0751@1|root,COG0751@2|Bacteria,1MV2F@1224|Proteobacteria,1RNR3@1236|Gammaproteobacteria,1XENS@135618|Methylococcales	135618|Methylococcales	J	Glycyl-tRNA synthetase beta subunit	glyS	-	6.1.1.14	ko:K01879	ko00970,map00970	M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_1,tRNA_synt_2f
k141_7317_1	1123261.AXDW01000002_gene1648	2.31e-115	343.0	COG0372@1|root,COG0372@2|Bacteria,1MUKX@1224|Proteobacteria,1RNDK@1236|Gammaproteobacteria,1X3KV@135614|Xanthomonadales	135614|Xanthomonadales	C	Belongs to the citrate synthase family	gltA	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
k141_5485_1	1122194.AUHU01000003_gene2391	1.44e-63	207.0	COG0577@1|root,COG0577@2|Bacteria,1MX7X@1224|Proteobacteria,1RRH7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	V	ABC-type antimicrobial peptide transport system, permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
k141_7888_1	159749.E7BWP2	2.26e-32	114.0	COG0254@1|root,2S1BJ@2759|Eukaryota	2759|Eukaryota	J	rRNA binding	rpl31	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009526,GO:0009532,GO:0009536,GO:0009570,GO:0009941,GO:0031967,GO:0031975,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464	-	ko:K02909	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31
k141_7318_1	631362.Thi970DRAFT_04271	1.6e-88	275.0	COG0606@1|root,COG0606@2|Bacteria,1MU4R@1224|Proteobacteria,1RMB9@1236|Gammaproteobacteria,1WWMF@135613|Chromatiales	135613|Chromatiales	O	PFAM Magnesium chelatase, ChlI subunit	-	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
k141_548_2	159749.E7BWE4	4.69e-186	522.0	COG0702@1|root,KOG1203@2759|Eukaryota,2XF8I@2836|Bacillariophyta	2836|Bacillariophyta	G	NmrA-like family	ycf39	-	-	-	-	-	-	-	-	-	-	-	NmrA
k141_9120_1	313594.PI23P_05182	4.98e-14	69.3	COG4232@1|root,COG4232@2|Bacteria,4PM8A@976|Bacteroidetes,1IJMD@117743|Flavobacteriia,3VWTB@52959|Polaribacter	976|Bacteroidetes	CO	Highly conserved protein containing a thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	Thioredox_DsbH,Thioredoxin_2,Thioredoxin_7
k141_9120_2	880071.Fleli_3835	1.58e-54	188.0	COG1629@1|root,COG4771@2|Bacteria,4NF05@976|Bacteroidetes,47K7I@768503|Cytophagia	976|Bacteroidetes	P	Outer membrane receptor for ferrienterochelin and colicins	-	-	-	ko:K16089	-	-	-	-	ko00000,ko02000	1.B.14.1,1.B.14.10	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k141_3598_1	314278.NB231_12104	9.31e-74	228.0	COG3384@1|root,COG3384@2|Bacteria,1MXJZ@1224|Proteobacteria,1RR5P@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	dioxygenase	ygiD	GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0046566,GO:0051213,GO:0055114	-	ko:K15777	ko00965,map00965	-	R08836	RC00387	ko00000,ko00001,ko01000	-	-	-	LigB
k141_1165_1	1137281.D778_02033	2.29e-18	84.0	COG1197@1|root,COG1197@2|Bacteria,4NEPA@976|Bacteroidetes,1HWS4@117743|Flavobacteriia	976|Bacteroidetes	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
k141_1165_2	983544.Lacal_0790	5.51e-29	114.0	COG0526@1|root,COG0526@2|Bacteria,4NHEC@976|Bacteroidetes,1HXZF@117743|Flavobacteriia	976|Bacteroidetes	CO	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,DUF4369,Thioredoxin_8
k141_1783_2	159749.E7BWI8	4.57e-45	150.0	COG0712@1|root,KOG1662@2759|Eukaryota,2XERP@2836|Bacillariophyta	2836|Bacillariophyta	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpD	-	-	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	OSCP
k141_7320_1	745014.OMB55_00014460	3.71e-108	334.0	COG3544@1|root,COG3544@2|Bacteria,1N0KY@1224|Proteobacteria,1SBTF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Domain of unknown function (DUF305)	-	-	-	-	-	-	-	-	-	-	-	-	DUF305
k141_4866_1	448385.sce2138	2.02e-09	63.5	COG2132@1|root,COG2132@2|Bacteria,1N9H3@1224|Proteobacteria,437UT@68525|delta/epsilon subdivisions,2WYPB@28221|Deltaproteobacteria,2YUNB@29|Myxococcales	28221|Deltaproteobacteria	Q	Multicopper oxidase	-	-	1.16.3.3	ko:K22349	-	-	-	-	ko00000,ko01000	-	-	-	-
k141_7890_1	1121875.KB907547_gene3041	1.59e-89	275.0	2CC76@1|root,3435K@2|Bacteria,4P48D@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_8532_1	1442598.JABW01000001_gene1816	1.01e-18	90.5	COG2304@1|root,COG2931@1|root,COG4254@1|root,COG2304@2|Bacteria,COG2931@2|Bacteria,COG4254@2|Bacteria,1MU7T@1224|Proteobacteria,43DFT@68525|delta/epsilon subdivisions	1224|Proteobacteria	Q	COG2931, RTX toxins and related Ca2 -binding proteins	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Big_3_2,VWA_2
k141_3023_1	526226.Gbro_4833	9.19e-09	60.5	COG1678@1|root,COG1678@2|Bacteria,2GNRA@201174|Actinobacteria,4GC26@85026|Gordoniaceae	201174|Actinobacteria	K	Uncharacterized ACR, COG1678	-	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K07735	-	-	-	-	ko00000,ko03000	-	-	-	DUF179
k141_3600_1	2340.JV46_03130	2.37e-133	390.0	COG4487@1|root,COG4487@2|Bacteria,1R5G1@1224|Proteobacteria,1RZAP@1236|Gammaproteobacteria,1J9KY@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Uncharacterized protein conserved in bacteria (DUF2130)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2130
k141_1785_1	1304888.ATWF01000001_gene1554	4.79e-85	263.0	COG0050@1|root,COG0050@2|Bacteria,2GF08@200930|Deferribacteres	200930|Deferribacteres	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
k141_4257_1	1198232.CYCME_0743	7.52e-124	362.0	COG0050@1|root,COG0050@2|Bacteria,1MVC0@1224|Proteobacteria,1RMYX@1236|Gammaproteobacteria,45ZSW@72273|Thiotrichales	72273|Thiotrichales	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
k141_5908_1	1288494.EBAPG3_11860	6.4e-38	142.0	COG0642@1|root,COG2205@2|Bacteria,1N17V@1224|Proteobacteria,2WEJE@28216|Betaproteobacteria,372ZN@32003|Nitrosomonadales	28216|Betaproteobacteria	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	cpxA	-	2.7.13.3	ko:K02484,ko:K07640,ko:K07642	ko01503,ko02020,map01503,map02020	M00447,M00450,M00645,M00646,M00648,M00727,M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
k141_7140_1	35128.Thapsdraft1350	1.35e-71	218.0	28NRD@1|root,2QTZ8@2759|Eukaryota,2XFHA@2836|Bacillariophyta	2836|Bacillariophyta	O	Photosystem I reaction centre subunit III	-	-	-	ko:K02694	ko00195,ko01100,map00195,map01100	M00163	-	-	ko00000,ko00001,ko00002,ko00194	-	-	-	PSI_PsaF
k141_2824_1	1380391.JIAS01000014_gene1998	2.12e-61	213.0	COG2902@1|root,COG2902@2|Bacteria,1MXNV@1224|Proteobacteria,2TS89@28211|Alphaproteobacteria,2JPCA@204441|Rhodospirillales	204441|Rhodospirillales	E	NAD-specific glutamate dehydrogenase	gdhA	-	1.4.1.2	ko:K15371	ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100	-	R00243	RC00006,RC02799	ko00000,ko00001,ko01000	-	-	-	Bac_GDH
k141_4684_1	1408433.JHXV01000018_gene3847	6.43e-82	256.0	COG0334@1|root,COG0334@2|Bacteria,4NEBH@976|Bacteroidetes,1HY7D@117743|Flavobacteriia,2PA92@246874|Cryomorphaceae	976|Bacteroidetes	C	Belongs to the Glu Leu Phe Val dehydrogenases family	gdhA	-	1.4.1.4	ko:K00262	ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100	-	R00248	RC00006,RC02799	ko00000,ko00001,ko01000	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
k141_4059_1	243233.MCA0195	3.59e-78	247.0	COG1690@1|root,COG1690@2|Bacteria,1MUHA@1224|Proteobacteria,1RMXH@1236|Gammaproteobacteria,1XE7S@135618|Methylococcales	135618|Methylococcales	S	Belongs to the RtcB family	rtcB	-	6.5.1.3	ko:K14415	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RtcB
k141_8937_1	159749.K0SXC9	2.23e-62	224.0	29N4Q@1|root,2RVF7@2759|Eukaryota,2XBJX@2836|Bacillariophyta	159749.K0SXC9|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_5909_1	998674.ATTE01000001_gene1789	1.06e-40	143.0	COG2896@1|root,COG2896@2|Bacteria,1MW3W@1224|Proteobacteria,1RR68@1236|Gammaproteobacteria,460AH@72273|Thiotrichales	72273|Thiotrichales	H	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate	moaA	-	4.1.99.22	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394	RC03420	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Mob_synth_C,Radical_SAM
k141_5909_2	998674.ATTE01000001_gene1788	1.07e-35	130.0	COG1526@1|root,COG1526@2|Bacteria,1MY28@1224|Proteobacteria,1RYH6@1236|Gammaproteobacteria,45ZY6@72273|Thiotrichales	72273|Thiotrichales	C	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH	fdhD	-	-	ko:K02379	-	-	-	-	ko00000	-	-	-	FdhD-NarQ
k141_6529_2	357804.Ping_2652	2.91e-28	116.0	COG2826@1|root,COG2826@2|Bacteria,1MWI0@1224|Proteobacteria,1RRSE@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	IS30 family	ISPlu1B	-	-	ko:K07482	-	-	-	-	ko00000	-	-	-	HTH_38,rve
k141_2826_1	247634.GPB2148_858	1.19e-30	120.0	COG0477@1|root,COG2814@2|Bacteria,1MVSH@1224|Proteobacteria,1RYB9@1236|Gammaproteobacteria	1236|Gammaproteobacteria	EGP	COG0477 Permeases of the major facilitator superfamily	tetA	-	-	ko:K08151	-	M00668	-	-	ko00000,ko00002,ko01504,ko02000	2.A.1.2.38,2.A.1.2.39,2.A.1.2.4,2.A.1.2.41,2.A.1.2.68,2.A.1.2.75	-	-	MFS_1,Sugar_tr
k141_2826_2	339670.Bamb_5079	2.22e-21	89.7	COG1028@1|root,COG1028@2|Bacteria,1MWGC@1224|Proteobacteria,2VHJE@28216|Betaproteobacteria,1K1EK@119060|Burkholderiaceae	28216|Betaproteobacteria	IQ	PFAM short-chain dehydrogenase reductase SDR	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
k141_3424_1	391937.NA2_00735	9.62e-12	64.7	COG0059@1|root,COG0059@2|Bacteria,1MV7M@1224|Proteobacteria,2TRXI@28211|Alphaproteobacteria,43IM9@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	EH	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate	ilvC	-	1.1.1.86	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R03051,R04439,R04440,R05068,R05069,R05071	RC00726,RC00836,RC00837,RC01726	ko00000,ko00001,ko00002,ko01000	-	-	-	IlvC,IlvN
k141_3424_2	1121935.AQXX01000141_gene2012	3.5e-54	178.0	COG1183@1|root,COG1183@2|Bacteria,1MWD9@1224|Proteobacteria,1RPBB@1236|Gammaproteobacteria,1XIQ5@135619|Oceanospirillales	135619|Oceanospirillales	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pssA	-	2.7.8.8	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	M00093	R01800	RC00002,RC00017,RC02795	ko00000,ko00001,ko00002,ko01000	-	-	-	CDP-OH_P_transf
k141_7710_1	1175306.GWL_40410	2.8e-18	86.3	COG0758@1|root,COG0758@2|Bacteria,1MVF6@1224|Proteobacteria,2VH3W@28216|Betaproteobacteria,47340@75682|Oxalobacteraceae	28216|Betaproteobacteria	LU	DNA recombination-mediator protein A	smf	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A
k141_8938_1	1232410.KI421422_gene2071	2.08e-51	183.0	COG0542@1|root,COG0542@2|Bacteria,1MURH@1224|Proteobacteria,42M9S@68525|delta/epsilon subdivisions,2WJSZ@28221|Deltaproteobacteria,43S73@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
k141_8938_2	570952.ATVH01000017_gene1808	1.02e-05	46.6	COG0044@1|root,COG0044@2|Bacteria,1MVXY@1224|Proteobacteria,2TSTM@28211|Alphaproteobacteria,2JPYU@204441|Rhodospirillales	204441|Rhodospirillales	F	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily	pyrC	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
k141_4061_1	1229909.NSED_01140	1.34e-38	135.0	COG0110@1|root,arCOG01848@2157|Archaea,41SJ0@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Hexapeptide repeat of succinyl-transferase	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
k141_4061_2	436308.Nmar_0246	3.72e-47	151.0	COG2835@1|root,arCOG04124@2157|Archaea,41STB@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Trm112p-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Trm112p
k141_1594_1	1294273.roselon_00420	2.06e-74	235.0	COG4603@1|root,COG4603@2|Bacteria,1MX6V@1224|Proteobacteria,2TRXS@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
k141_5298_1	391613.RTM1035_08979	2.5e-112	327.0	COG0708@1|root,COG0708@2|Bacteria,1MVII@1224|Proteobacteria,2TR5J@28211|Alphaproteobacteria,46NKH@74030|Roseovarius	28211|Alphaproteobacteria	L	COG0708 Exonuclease III	xth	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
k141_6531_1	1238182.C882_0004	1.79e-78	245.0	COG2170@1|root,COG2170@2|Bacteria,1MX4N@1224|Proteobacteria,2TR20@28211|Alphaproteobacteria,2JPF7@204441|Rhodospirillales	204441|Rhodospirillales	H	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity	-	-	-	ko:K06048	-	-	-	-	ko00000,ko01000	-	-	-	GCS2
k141_5911_1	999611.KI421504_gene1954	1.07e-35	133.0	COG0459@1|root,COG0459@2|Bacteria,1MURR@1224|Proteobacteria,2TS07@28211|Alphaproteobacteria,280FA@191028|Leisingera	28211|Alphaproteobacteria	O	TCP-1/cpn60 chaperonin family	groL	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
k141_5911_2	740709.A10D4_05787	4.42e-33	126.0	COG0459@1|root,COG0459@2|Bacteria,1MURR@1224|Proteobacteria,1RMTB@1236|Gammaproteobacteria,2QF5R@267893|Idiomarinaceae	1236|Gammaproteobacteria	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0008144,GO:0008150,GO:0009266,GO:0009314,GO:0009405,GO:0009408,GO:0009628,GO:0009987,GO:0016032,GO:0016462,GO:0016465,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019058,GO:0019068,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0035821,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0044183,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051704,GO:0051817,GO:0052047,GO:0052212,GO:0061077,GO:0097159,GO:0097367,GO:0101031,GO:1901265,GO:1901363,GO:1990220	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
k141_9595_1	1449351.RISW2_10800	2.07e-62	209.0	COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,2TSB1@28211|Alphaproteobacteria,4KKKQ@93682|Roseivivax	28211|Alphaproteobacteria	EH	Belongs to the TPP enzyme family	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
k141_8340_1	1336803.PHEL49_1737	1.98e-25	104.0	COG0550@1|root,COG0551@1|root,COG0550@2|Bacteria,COG0551@2|Bacteria,4NE6R@976|Bacteroidetes,1HWYU@117743|Flavobacteriia,3VVXA@52959|Polaribacter	976|Bacteroidetes	L	Bacterial DNA topoisomeraes I ATP-binding domain	topB	-	5.99.1.2	ko:K03169	-	-	-	-	ko00000,ko01000,ko03032	-	-	-	Topoisom_bac,Toprim
k141_8340_2	1250006.JHZZ01000001_gene2821	1.68e-45	162.0	COG0550@1|root,COG0551@1|root,COG0550@2|Bacteria,COG0551@2|Bacteria,4NE6R@976|Bacteroidetes,1HWYU@117743|Flavobacteriia,3VVXA@52959|Polaribacter	976|Bacteroidetes	L	Bacterial DNA topoisomeraes I ATP-binding domain	topB	-	5.99.1.2	ko:K03169	-	-	-	-	ko00000,ko01000,ko03032	-	-	-	Topoisom_bac,Toprim
k141_4687_2	2880.D1J7C6	1.1e-16	76.3	2CNI2@1|root,2QWGG@2759|Eukaryota	2759|Eukaryota	S	photosynthesis	ycf4	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006091,GO:0008150,GO:0008152,GO:0009507,GO:0009534,GO:0009535,GO:0009536,GO:0009579,GO:0009987,GO:0015979,GO:0016020,GO:0016043,GO:0019684,GO:0022607,GO:0031976,GO:0031984,GO:0034357,GO:0034622,GO:0042651,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043933,GO:0044085,GO:0044237,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044436,GO:0044444,GO:0044446,GO:0044464,GO:0048564,GO:0051082,GO:0055035,GO:0065003,GO:0071840	-	-	-	-	-	-	-	-	-	-	Ycf4
k141_3425_1	670292.JH26_22965	2.64e-76	234.0	COG0861@1|root,COG0861@2|Bacteria,1MWC9@1224|Proteobacteria,2TTT6@28211|Alphaproteobacteria,1JTNI@119045|Methylobacteriaceae	28211|Alphaproteobacteria	P	PFAM Integral membrane protein TerC	terC	-	-	-	-	-	-	-	-	-	-	-	TerC
k141_7144_1	265072.Mfla_0642	3.19e-37	135.0	COG0204@1|root,COG0204@2|Bacteria,1MY51@1224|Proteobacteria,2VNAX@28216|Betaproteobacteria,2KKR3@206350|Nitrosomonadales	206350|Nitrosomonadales	I	Phosphate acyltransferases	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
k141_363_1	1049564.TevJSym_ap00050	1.64e-91	293.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,1RN2C@1236|Gammaproteobacteria,1J57S@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	P	cation transport ATPase	-	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase,YHS
k141_5912_1	371731.Rsw2DRAFT_0670	2.89e-48	162.0	COG0586@1|root,COG0586@2|Bacteria,1Q68Z@1224|Proteobacteria,2UA40@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
k141_6532_1	1232683.ADIMK_0788	6.98e-65	209.0	COG4972@1|root,COG4972@2|Bacteria,1MX8P@1224|Proteobacteria,1RN8S@1236|Gammaproteobacteria,465IC@72275|Alteromonadaceae	1236|Gammaproteobacteria	NU	COG4972 Tfp pilus assembly protein, ATPase PilM	pilM	-	-	ko:K02662	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilM_2
k141_8341_1	292415.Tbd_2803	7.25e-91	273.0	COG0356@1|root,COG0356@2|Bacteria,1MV87@1224|Proteobacteria,2VHR5@28216|Betaproteobacteria,1KRNA@119069|Hydrogenophilales	119069|Hydrogenophilales	C	ATP synthase A chain	-	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
k141_2828_1	1188256.BASI01000001_gene411	6.14e-98	315.0	COG0085@1|root,COG0085@2|Bacteria,1MUC4@1224|Proteobacteria,2TS7S@28211|Alphaproteobacteria,3FCSH@34008|Rhodovulum	28211|Alphaproteobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
k141_364_1	1116369.KB890024_gene1577	2.92e-84	268.0	COG0446@1|root,COG1902@1|root,COG0446@2|Bacteria,COG1902@2|Bacteria,1MVE0@1224|Proteobacteria,2TQV0@28211|Alphaproteobacteria,43HZ9@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	C	NADH flavin oxidoreductase NADH oxidase	stcD	-	-	ko:K21833	-	-	-	-	ko00000	-	-	-	NAD_binding_8,Oxidored_FMN,Pyr_redox_2
k141_3427_1	1121930.AQXG01000001_gene1621	3.51e-20	89.7	COG1796@1|root,COG1796@2|Bacteria	2|Bacteria	L	DNA-directed DNA polymerase activity	polX	-	-	ko:K02347,ko:K04477	-	-	-	-	ko00000,ko03400	-	-	-	DNA_pol_B_palm,DNA_pol_B_thumb,HHH_5,HHH_8,PHP
k141_5301_1	944435.AXAJ01000020_gene5004	2.24e-54	180.0	COG0179@1|root,COG0179@2|Bacteria,1QUQP@1224|Proteobacteria,2VQEI@28216|Betaproteobacteria,1K1V4@119060|Burkholderiaceae	28216|Betaproteobacteria	Q	fumarylacetoacetate (FAA) hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	DUF2437,FAA_hydrolase
k141_2829_1	395019.Bmul_1961	1.5e-30	122.0	COG1529@1|root,COG1529@2|Bacteria,1QTTJ@1224|Proteobacteria,2VHB9@28216|Betaproteobacteria,1K63J@119060|Burkholderiaceae	28216|Betaproteobacteria	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	iorB	-	1.3.99.16	ko:K07303	-	-	-	-	ko00000,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
k141_7146_1	765911.Thivi_2932	1.18e-79	246.0	COG0176@1|root,COG0176@2|Bacteria,1MWQ8@1224|Proteobacteria,1RMS0@1236|Gammaproteobacteria,1WX05@135613|Chromatiales	135613|Chromatiales	H	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	tal	-	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
k141_4689_1	159749.E7BWJ3	9.07e-145	427.0	28JJ8@1|root,2QRYE@2759|Eukaryota	2759|Eukaryota	C	chlorophyll binding	psaA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009534,GO:0009535,GO:0009536,GO:0009579,GO:0016020,GO:0031976,GO:0031984,GO:0034357,GO:0042651,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044436,GO:0044444,GO:0044446,GO:0044464,GO:0055035	-	ko:K02689,ko:K02690	ko00195,ko01100,map00195,map01100	M00163	-	-	ko00000,ko00001,ko00002,ko00194	-	-	-	PsaA_PsaB
k141_7711_2	400682.PAC_15698807	4.84e-08	59.7	COG2801@1|root,KOG0017@2759|Eukaryota,3A8FB@33154|Opisthokonta	33154|Opisthokonta	L	transposition, RNA-mediated	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_7712_1	205918.Psyr_4935	8.55e-23	95.9	COG1088@1|root,COG1088@2|Bacteria,1MU5E@1224|Proteobacteria,1RP7G@1236|Gammaproteobacteria,1Z6YX@136849|Pseudomonas syringae group	1236|Gammaproteobacteria	M	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily	rfbB	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
k141_7712_2	34506.g2403	9.43e-39	144.0	COG1004@1|root,COG1088@1|root,KOG0747@2759|Eukaryota,KOG2666@2759|Eukaryota,39ADA@33154|Opisthokonta,3BF2W@33208|Metazoa,3CWS2@33213|Bilateria,40FTF@6231|Nematoda,1KYEF@119089|Chromadorea,40UIK@6236|Rhabditida	33208|Metazoa	G	Male sterility protein	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase_2,GDP_Man_Dehyd,UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
k141_5303_1	977880.RALTA_A2112	6.7e-107	319.0	COG0133@1|root,COG0133@2|Bacteria,1MUS8@1224|Proteobacteria,2VHV3@28216|Betaproteobacteria,1JZSI@119060|Burkholderiaceae	28216|Betaproteobacteria	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB	GO:0000162,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0042802,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.2.1.20	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
k141_2831_1	1380391.JIAS01000014_gene2168	8.45e-69	221.0	COG1364@1|root,COG1364@2|Bacteria,1MU0T@1224|Proteobacteria,2TS98@28211|Alphaproteobacteria,2JPX5@204441|Rhodospirillales	204441|Rhodospirillales	E	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate	argJ	-	2.3.1.1,2.3.1.35	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259,R02282	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	ArgJ
k141_3429_1	1528106.JRJE01000020_gene2403	2.47e-22	97.4	COG2303@1|root,COG2303@2|Bacteria,1MV19@1224|Proteobacteria,2TQKQ@28211|Alphaproteobacteria,2JV9J@204441|Rhodospirillales	204441|Rhodospirillales	E	GMC oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GMC_oxred_C,GMC_oxred_N
k141_7147_2	1047013.AQSP01000049_gene2263	3.31e-39	147.0	COG0399@1|root,COG0399@2|Bacteria	2|Bacteria	E	UDP-4-amino-4-deoxy-L-arabinose aminotransferase	-	-	2.6.1.102	ko:K13010	ko00520,map00520	-	R10460	RC00006,RC00781	ko00000,ko00001,ko01000,ko01005,ko01007	-	-	-	DegT_DnrJ_EryC1,Y2_Tnp,Zn_Tnp_IS91
k141_366_1	159749.E7BWK9	5.28e-172	494.0	COG0459@1|root,KOG0356@2759|Eukaryota,2XBJD@2836|Bacillariophyta	2759|Eukaryota	O	Belongs to the chaperonin (HSP60) family	groL	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009536,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
k141_6535_1	382464.ABSI01000011_gene2573	4.14e-35	139.0	COG0689@1|root,COG2931@1|root,COG3055@1|root,COG3898@1|root,COG0689@2|Bacteria,COG2931@2|Bacteria,COG3055@2|Bacteria,COG3898@2|Bacteria	2|Bacteria	D	HemY domain protein	-	-	-	ko:K01991,ko:K02498,ko:K20276	ko02024,ko02026,map02024,map02026	-	-	-	ko00000,ko00001,ko02000	1.B.18	-	-	Beta_helix,Cadherin_3,He_PIG,HemolysinCabind,Kelch_1,Laminin_G_3
k141_1598_1	1207063.P24_03261	3.07e-52	178.0	COG3118@1|root,COG3118@2|Bacteria,1MV0R@1224|Proteobacteria,2TS5X@28211|Alphaproteobacteria,2JQCS@204441|Rhodospirillales	204441|Rhodospirillales	O	Thioredoxin	-	-	-	ko:K05838	-	-	-	-	ko00000,ko03110	-	-	-	TPR_19,TPR_20,Thioredoxin
k141_4691_1	2850.Phatr50076	3.77e-93	300.0	KOG4471@1|root,KOG4471@2759|Eukaryota,2XBDR@2836|Bacillariophyta	2836|Bacillariophyta	IU	Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily	-	-	-	-	-	-	-	-	-	-	-	-	Myotub-related
k141_8943_1	498211.CJA_1448	1.68e-82	260.0	COG0260@1|root,COG0260@2|Bacteria,1MUF9@1224|Proteobacteria,1RNM1@1236|Gammaproteobacteria,1FGHX@10|Cellvibrio	1236|Gammaproteobacteria	E	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides	pepA	GO:0001073,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0004177,GO:0005488,GO:0006139,GO:0006259,GO:0006276,GO:0006310,GO:0006351,GO:0006355,GO:0006508,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0009056,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016787,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019538,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0042150,GO:0043170,GO:0043171,GO:0043244,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:0140096,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1903506,GO:2000112,GO:2001141	3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17,Peptidase_M17_N
k141_9600_1	1415756.JQMY01000001_gene1399	1.11e-82	257.0	COG2807@1|root,COG2807@2|Bacteria,1QV77@1224|Proteobacteria,2TT90@28211|Alphaproteobacteria,2PDBQ@252301|Oceanicola	28211|Alphaproteobacteria	P	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
k141_7713_1	279714.FuraDRAFT_0414	2.02e-92	302.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1MU7B@1224|Proteobacteria,2VHUY@28216|Betaproteobacteria,2KPY3@206351|Neisseriales	206351|Neisseriales	E	glutamate synthase	gltB	-	1.4.1.13,1.4.1.14	ko:K00265	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
k141_367_2	983917.RGE_44760	9.04e-80	245.0	COG0057@1|root,COG0057@2|Bacteria,1MU93@1224|Proteobacteria,2VHHG@28216|Betaproteobacteria,1KKA5@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	gapA	GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
k141_2222_1	1163617.SCD_n01186	1.71e-66	218.0	COG4623@1|root,COG4623@2|Bacteria,1MWDS@1224|Proteobacteria,2VKSN@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella	mltF	GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944	-	ko:K18691	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	SBP_bac_3,SLT
k141_6536_1	335543.Sfum_3450	6.95e-60	199.0	COG2270@1|root,COG2270@2|Bacteria,1MWXB@1224|Proteobacteria,42N2B@68525|delta/epsilon subdivisions,2WJS9@28221|Deltaproteobacteria,2MQ4E@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Vacuole effluxer Atg22 like	-	-	-	ko:K06902	ko04138,map04138	-	-	-	ko00000,ko00001,ko02000,ko04131	2.A.1.24,9.A.15.1	-	-	ATG22
k141_444_1	1469245.JFBG01000027_gene1495	1.26e-98	305.0	COG4147@1|root,COG4147@2|Bacteria,1MVJ8@1224|Proteobacteria,1RN0R@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	actP	-	-	ko:K14393	-	-	-	-	ko00000,ko02000	2.A.21.7	-	-	SSF
k141_9013_1	95619.PM1_0211260	4.88e-33	120.0	COG3749@1|root,COG3749@2|Bacteria,1RJR9@1224|Proteobacteria,1S64S@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	protein conserved in bacteria	IV02_15230	-	-	-	-	-	-	-	-	-	-	-	DUF934
k141_9013_2	94624.Bpet4537	8.69e-68	221.0	COG0155@1|root,COG0155@2|Bacteria,1MVVB@1224|Proteobacteria,2VIYX@28216|Betaproteobacteria,3T1UQ@506|Alcaligenaceae	28216|Betaproteobacteria	C	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate	cysI	-	1.8.1.2,1.8.7.1	ko:K00381,ko:K00392	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00176	R00858,R00859,R03600	RC00065	ko00000,ko00001,ko00002,ko01000	-	-	-	NIR_SIR,NIR_SIR_ferr
k141_4763_1	32042.PstZobell_18625	2.26e-50	171.0	COG3039@1|root,COG3039@2|Bacteria,1MUVI@1224|Proteobacteria,1RQVT@1236|Gammaproteobacteria,1Z1TJ@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	L	COG3666 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_6,DUF772
k141_4144_1	1239962.C943_00088	2.4e-62	197.0	COG4660@1|root,COG4660@2|Bacteria,4NHHP@976|Bacteroidetes	976|Bacteroidetes	C	Part of a membrane complex involved in electron transport	rnfE	-	-	ko:K03613	-	-	-	-	ko00000	-	-	-	Rnf-Nqr
k141_1056_1	187272.Mlg_0413	8.07e-78	248.0	COG0312@1|root,COG0312@2|Bacteria,1MUVW@1224|Proteobacteria,1RPJF@1236|Gammaproteobacteria,1WWPA@135613|Chromatiales	135613|Chromatiales	S	modulator of DNA gyrase	-	-	-	ko:K03592	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
k141_4142_1	1123360.thalar_00355	4.24e-24	92.4	COG1977@1|root,COG1977@2|Bacteria,1N0IE@1224|Proteobacteria,2UF4F@28211|Alphaproteobacteria	28211|Alphaproteobacteria	H	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin	moaD	-	-	ko:K03636	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
k141_4142_2	402881.Plav_2273	1.92e-59	187.0	COG0314@1|root,COG0314@2|Bacteria,1RGUX@1224|Proteobacteria,2U73K@28211|Alphaproteobacteria,1JP07@119043|Rhodobiaceae	28211|Alphaproteobacteria	H	MoaE protein	moaE	-	2.8.1.12	ko:K03635	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09395	RC02507	ko00000,ko00001,ko01000	-	-	-	MoaE
k141_442_1	987059.RBXJA2T_15573	1.23e-21	94.7	COG0497@1|root,COG0497@2|Bacteria,1MUNP@1224|Proteobacteria,2VHHA@28216|Betaproteobacteria,1KK5K@119065|unclassified Burkholderiales	28216|Betaproteobacteria	L	May be involved in recombinational repair of damaged DNA	recN	-	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	SMC_N
k141_2294_1	501479.ACNW01000089_gene2449	9.83e-79	249.0	COG3666@1|root,COG3666@2|Bacteria,1N3QR@1224|Proteobacteria,2TRXG@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	Transposase	-	-	-	ko:K07487	-	-	-	-	ko00000	-	-	-	DDE_Tnp_1,DDE_Tnp_1_6,DUF772
k141_7221_1	1123354.AUDR01000015_gene261	2.59e-66	210.0	COG4105@1|root,COG4105@2|Bacteria,1MVS5@1224|Proteobacteria,2VH6I@28216|Betaproteobacteria,1KREX@119069|Hydrogenophilales	119069|Hydrogenophilales	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamD	-	-	ko:K05807	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	YfiO
k141_7785_1	1207063.P24_03241	2.13e-35	135.0	COG2270@1|root,COG2270@2|Bacteria,1MWXB@1224|Proteobacteria,2TSCV@28211|Alphaproteobacteria,2JQ6C@204441|Rhodospirillales	204441|Rhodospirillales	S	Vacuole effluxer Atg22 like	-	-	-	ko:K06902	ko04138,map04138	-	-	-	ko00000,ko00001,ko02000,ko04131	2.A.1.24,9.A.15.1	-	-	ATG22
k141_9011_1	999611.KI421504_gene25	3.84e-96	290.0	COG1454@1|root,COG1454@2|Bacteria,1MVPH@1224|Proteobacteria,2TSX8@28211|Alphaproteobacteria,27ZTW@191028|Leisingera	28211|Alphaproteobacteria	C	Iron-containing alcohol dehydrogenase	mdh1	-	1.1.1.1,1.1.1.61	ko:K00001,ko:K00043	ko00010,ko00071,ko00350,ko00625,ko00626,ko00650,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00010,map00071,map00350,map00625,map00626,map00650,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220	-	R00623,R00754,R01644,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	Fe-ADH
k141_9670_1	159749.E7BWL8	1.21e-13	69.3	COG0088@1|root,KOG1624@2759|Eukaryota	2759|Eukaryota	J	structural constituent of ribosome	rpl4	GO:0000311,GO:0000313,GO:0000315,GO:0003674,GO:0003676,GO:0003723,GO:0003727,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008187,GO:0008266,GO:0009058,GO:0009059,GO:0009507,GO:0009532,GO:0009534,GO:0009535,GO:0009536,GO:0009547,GO:0009570,GO:0009579,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022626,GO:0031976,GO:0031984,GO:0032991,GO:0034357,GO:0034641,GO:0034645,GO:0042651,GO:0043043,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044436,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0055035,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02926	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L4
k141_9670_2	2880.D1J750	1.08e-29	109.0	COG0089@1|root,2SAK4@2759|Eukaryota	2759|Eukaryota	J	rRNA binding	rpl23	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009507,GO:0009536,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02892	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L23
k141_6608_1	446466.Cfla_3006	1.03e-08	60.8	COG2186@1|root,COG2186@2|Bacteria,2GJ82@201174|Actinobacteria	201174|Actinobacteria	K	gntR family	-	-	-	ko:K05799	-	-	-	-	ko00000,ko03000	-	-	-	FCD,GntR
k141_1054_1	1380393.JHVP01000005_gene3589	1.14e-72	231.0	COG1181@1|root,COG1181@2|Bacteria,2I7XS@201174|Actinobacteria,4EWIZ@85013|Frankiales	2|Bacteria	M	Belongs to the D-alanine--D-alanine ligase family	-	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	ATP-grasp,ATP-grasp_4,Dala_Dala_lig_C,Dala_Dala_lig_N
k141_5381_1	1049564.TevJSym_ad00400	2.67e-95	289.0	COG0436@1|root,COG0436@2|Bacteria,1MWS8@1224|Proteobacteria,1RPGJ@1236|Gammaproteobacteria,1J4YQ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	E	COG0436 Aspartate tyrosine aromatic aminotransferase	dapC	-	2.6.1.17	ko:K14261,ko:K14267	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R04475	RC00006	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
k141_4143_1	45351.EDO48449	3.23e-29	117.0	29WUB@1|root,2RXQC@2759|Eukaryota,39WMB@33154|Opisthokonta	33154|Opisthokonta	-	-	-	-	-	-	-	-	-	-	-	-	-	-	PrpF
k141_443_1	543728.Vapar_4498	2.17e-90	281.0	COG3666@1|root,COG3666@2|Bacteria,1N3QR@1224|Proteobacteria,2VIE4@28216|Betaproteobacteria,4AJH7@80864|Comamonadaceae	28216|Betaproteobacteria	L	Transposase domain (DUF772)	-	-	-	ko:K07487	-	-	-	-	ko00000	-	-	-	DDE_Tnp_1,DDE_Tnp_1_6,DUF772
k141_4762_1	264198.Reut_B3773	1.56e-108	330.0	COG0028@1|root,COG0028@2|Bacteria,1MWUB@1224|Proteobacteria,2VMC1@28216|Betaproteobacteria,1K2XV@119060|Burkholderiaceae	28216|Betaproteobacteria	EH	Belongs to the TPP enzyme family	xsc	-	2.3.3.15	ko:K03852	ko00430,map00430	-	R05651	RC02903,RC02909	ko00000,ko00001,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
k141_9671_1	1049564.TevJSym_aq00700	2.83e-50	169.0	COG4658@1|root,COG4658@2|Bacteria,1MVY6@1224|Proteobacteria,1RMEU@1236|Gammaproteobacteria,1J55P@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	U	Part of a membrane complex involved in electron transport	rnfD	-	-	ko:K03614	-	-	-	-	ko00000	-	-	-	NQR2_RnfD_RnfE
k141_9671_2	269482.Bcep1808_3911	3.29e-06	50.1	COG0526@1|root,COG0526@2|Bacteria,1RAW3@1224|Proteobacteria,2VP3Z@28216|Betaproteobacteria,1K0KM@119060|Burkholderiaceae	28216|Betaproteobacteria	CO	Prolipoprotein diacylglyceryl transferase	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,LGT,Redoxin
k141_9074_1	472759.Nhal_0566	3e-98	300.0	COG0154@1|root,COG0154@2|Bacteria,1MUVQ@1224|Proteobacteria,1RP7E@1236|Gammaproteobacteria,1WWC9@135613|Chromatiales	135613|Chromatiales	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
k141_9074_2	1469245.JFBG01000040_gene1722	4.71e-75	239.0	COG0064@1|root,COG0064@2|Bacteria,1MUKG@1224|Proteobacteria,1RP7U@1236|Gammaproteobacteria,1WX4J@135613|Chromatiales	135613|Chromatiales	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	-	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
k141_6672_1	331869.BAL199_22262	3.88e-85	261.0	COG1893@1|root,COG1893@2|Bacteria,1QMH8@1224|Proteobacteria,2TSGW@28211|Alphaproteobacteria	28211|Alphaproteobacteria	H	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_7849_1	713587.THITH_14325	2.24e-128	401.0	COG0085@1|root,COG0085@2|Bacteria,1MUC4@1224|Proteobacteria,1RMK0@1236|Gammaproteobacteria,1WX4P@135613|Chromatiales	135613|Chromatiales	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	-	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
k141_508_1	519989.ECTPHS_05400	9.27e-92	290.0	COG2225@1|root,COG2225@2|Bacteria,1MVEV@1224|Proteobacteria,1RPVI@1236|Gammaproteobacteria,1WXV7@135613|Chromatiales	135613|Chromatiales	C	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA	glcB	-	2.3.3.9	ko:K01638	ko00620,ko00630,ko01100,ko01110,ko01120,ko01200,map00620,map00630,map01100,map01110,map01120,map01200	M00012	R00472	RC00004,RC00308,RC02747	ko00000,ko00001,ko00002,ko01000	-	-	-	Malate_synthase
k141_1122_1	1237149.C900_03873	7.72e-20	90.1	COG1295@1|root,COG1295@2|Bacteria,4NFY6@976|Bacteroidetes,47KA8@768503|Cytophagia	976|Bacteroidetes	S	TIGRFAM YihY family protein (not ribonuclease BN)	yfkH	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
k141_4213_1	159749.K0SPK0	3.14e-41	154.0	COG2801@1|root,2QT1S@2759|Eukaryota	2759|Eukaryota	L	transposition	-	-	-	-	-	-	-	-	-	-	-	-	RVT_1,rve
k141_3555_1	998088.B565_0080	7.34e-80	258.0	COG0210@1|root,COG0210@2|Bacteria,1MU0G@1224|Proteobacteria,1RNJI@1236|Gammaproteobacteria,1Y43B@135624|Aeromonadales	135624|Aeromonadales	L	DNA helicase	uvrD	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
k141_6673_2	404589.Anae109_1894	4.77e-32	121.0	COG0674@1|root,COG0674@2|Bacteria,1NBSJ@1224|Proteobacteria,42MS1@68525|delta/epsilon subdivisions,2WJ97@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM pyruvate flavodoxin ferredoxin oxidoreductase domain protein	-	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR_N
k141_8484_2	83406.HDN1F_37070	9.65e-23	98.6	COG2010@1|root,COG2010@2|Bacteria,1N3PN@1224|Proteobacteria,1RNS0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Nitrite reductase	nirS	-	1.7.2.1,1.7.99.1	ko:K15864	ko00910,ko01120,map00910,map01120	M00529	R00143,R00783,R00785	RC00086,RC02797	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytochrom_D1,Cytochrome_CBB3
k141_1123_1	1116375.VEJY3_04050	1.29e-121	360.0	COG1680@1|root,COG1680@2|Bacteria,1MY01@1224|Proteobacteria,1RNUI@1236|Gammaproteobacteria,1XZIB@135623|Vibrionales	135623|Vibrionales	V	Beta-lactamase	-	-	3.5.2.6	ko:K01467	ko01501,ko02020,map01501,map02020	M00628	R06363	RC01499	ko00000,ko00001,ko00002,ko01000	-	-	-	Beta-lactamase
k141_6051_1	367336.OM2255_03610	1.15e-97	294.0	COG0113@1|root,COG0113@2|Bacteria,1MWMW@1224|Proteobacteria,2TS3F@28211|Alphaproteobacteria	28211|Alphaproteobacteria	H	Belongs to the ALAD family	hemB	GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.2.1.24	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00036	RC00918,RC01781	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ALAD
k141_4832_1	1118153.MOY_10860	1.51e-52	186.0	COG0506@1|root,COG4230@1|root,COG0506@2|Bacteria,COG4230@2|Bacteria,1MV93@1224|Proteobacteria,1RN48@1236|Gammaproteobacteria,1XH7V@135619|Oceanospirillales	135619|Oceanospirillales	CE	Oxidizes proline to glutamate for use as a carbon and nitrogen source	putA	-	1.2.1.88,1.5.5.2	ko:K13821	ko00250,ko00330,ko01100,ko01110,ko01130,map00250,map00330,map01100,map01110,map01130	-	R00245,R00707,R00708,R01253,R04444,R04445,R05051	RC00080,RC00083,RC00216,RC00242,RC00255	ko00000,ko00001,ko01000,ko03000	-	-	-	Aldedh,Pro_dh,Pro_dh-DNA_bdg
k141_4832_2	1203568.HMPREF1484_01404	4.62e-17	80.5	COG1760@1|root,COG1760@2|Bacteria,2GJPA@201174|Actinobacteria,4FBCT@85020|Dermabacteraceae	201174|Actinobacteria	E	Serine dehydratase beta chain	-	-	4.3.1.17	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	-	R00220,R00590	RC00331,RC02600	ko00000,ko00001,ko01000	-	-	-	SDH_alpha,SDH_beta
k141_3556_1	1128421.JAGA01000003_gene2824	2.08e-85	268.0	COG1488@1|root,COG1488@2|Bacteria,2NNUE@2323|unclassified Bacteria	2|Bacteria	H	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP	pncB	GO:0001666,GO:0003674,GO:0003824,GO:0004516,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009605,GO:0009607,GO:0009628,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016763,GO:0016874,GO:0016879,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0019674,GO:0034355,GO:0034641,GO:0034654,GO:0036293,GO:0043094,GO:0043173,GO:0043207,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044403,GO:0044419,GO:0044464,GO:0046483,GO:0046496,GO:0047280,GO:0050896,GO:0051186,GO:0051188,GO:0051701,GO:0051704,GO:0051707,GO:0055086,GO:0070482,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0075136,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.4.21	ko:K00763	ko00760,ko01100,map00760,map01100	-	R01724	RC00033	ko00000,ko00001,ko01000	-	-	iYO844.BSU31750	NAPRTase
k141_5446_1	1342299.Z947_4182	1.1e-107	323.0	COG0277@1|root,COG0277@2|Bacteria,1MU6Y@1224|Proteobacteria,2TSG6@28211|Alphaproteobacteria,3ZVIX@60136|Sulfitobacter	28211|Alphaproteobacteria	C	FAD linked oxidases, C-terminal domain	glcD	-	1.1.3.15	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
k141_1743_1	1229909.NSED_06385	1.7e-52	175.0	COG0372@1|root,arCOG04237@2157|Archaea,41SAN@651137|Thaumarchaeota	651137|Thaumarchaeota	C	TIGRFAM 2-methylcitrate synthase citrate synthase II	-	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
k141_1744_1	1085623.GNIT_0713	5.99e-29	109.0	COG2885@1|root,COG2885@2|Bacteria,1RAB7@1224|Proteobacteria,1SS9U@1236|Gammaproteobacteria,468H0@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	COG2885 Outer membrane protein and related peptidoglycan-associated (lipo)proteins	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
k141_3558_1	883080.HMPREF9697_01356	1.53e-45	162.0	COG1012@1|root,COG1012@2|Bacteria,1QUBI@1224|Proteobacteria,2TSSD@28211|Alphaproteobacteria,3JSCW@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	Aldehyde dehydrogenase family	adhE	-	1.2.1.81,1.2.1.87	ko:K13922,ko:K15515	ko00640,map00640	-	R09097	RC00004,RC00184	ko00000,ko00001,ko01000	-	-	-	Aldedh
k141_2363_1	744979.R2A130_3260	1.06e-104	313.0	COG3243@1|root,COG3243@2|Bacteria,1MU68@1224|Proteobacteria,2VFW2@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	TIGRFAM poly(R)-hydroxyalkanoic acid synthase, class III, PhaC subunit	-	-	-	ko:K03821	ko00650,map00650	-	R04254	RC00004	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1,PhaC_N
k141_6675_1	1269813.ATUL01000013_gene246	9.82e-37	143.0	COG5000@1|root,COG5000@2|Bacteria,1MWKZ@1224|Proteobacteria,1RQ8B@1236|Gammaproteobacteria,1WXE6@135613|Chromatiales	135613|Chromatiales	T	signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,PAS_4,PAS_8
k141_7852_1	1509405.GV67_14030	4.98e-74	239.0	COG3666@1|root,COG3666@2|Bacteria,1QW5T@1224|Proteobacteria,2TWNW@28211|Alphaproteobacteria,4BP2N@82115|Rhizobiaceae	28211|Alphaproteobacteria	L	Transposase DDE domain	tnp*	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_6,DUF772
k141_6054_1	1245469.S58_58300	4.5e-61	204.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,2TR2W@28211|Alphaproteobacteria,3JRKR@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
k141_2982_2	644107.SL1157_1556	1.78e-64	202.0	COG0087@1|root,COG0087@2|Bacteria,1MUST@1224|Proteobacteria,2TRHB@28211|Alphaproteobacteria,4NA1E@97050|Ruegeria	28211|Alphaproteobacteria	J	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit	rplC	-	-	ko:K02906	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L3
k141_7282_2	13735.ENSPSIP00000001067	4.41e-114	363.0	KOG1075@1|root,KOG1075@2759|Eukaryota,39TZY@33154|Opisthokonta,3BI15@33208|Metazoa,3CYKV@33213|Bilateria,487I3@7711|Chordata,4962T@7742|Vertebrata	33208|Metazoa	S	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	2.3.1.15,2.4.2.29	ko:K04257,ko:K13506,ko:K15407	ko00561,ko00564,ko01100,ko01110,ko04740,map00561,map00564,map01100,map01110,map04740	M00089	R00851,R03789,R09380,R10209	RC00004,RC00039,RC00041,RC00063	ko00000,ko00001,ko00002,ko01000,ko01004,ko03016,ko04030	-	-	-	Exo_endo_phos_2,RVT_1
k141_4835_1	159749.E7BWI2	1.37e-17	81.3	COG0719@1|root,2QRGW@2759|Eukaryota,2XEEX@2836|Bacillariophyta	2836|Bacillariophyta	O	Uncharacterized protein family (UPF0051)	-	-	-	-	-	-	-	-	-	-	-	-	UPF0051
k141_4835_2	35128.Thapsdraft1319	1.31e-149	424.0	COG0396@1|root,2QS88@2759|Eukaryota,2XFH5@2836|Bacillariophyta	2836|Bacillariophyta	Q	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
k141_4217_1	1123514.KB905899_gene1880	6.86e-36	128.0	COG3748@1|root,COG3748@2|Bacteria,1RFIZ@1224|Proteobacteria,1S8F8@1236|Gammaproteobacteria,4638B@72273|Thiotrichales	72273|Thiotrichales	S	Urate oxidase N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	Urate_ox_N
k141_7854_1	314278.NB231_08335	1.61e-87	270.0	COG3385@1|root,COG3385@2|Bacteria,1MVRM@1224|Proteobacteria,1RRFT@1236|Gammaproteobacteria,1WZIC@135613|Chromatiales	135613|Chromatiales	L	COG3385 FOG Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
k141_3560_1	1229909.NSED_07060	3.85e-137	399.0	COG2132@1|root,arCOG03914@2157|Archaea,41SZT@651137|Thaumarchaeota	651137|Thaumarchaeota	Q	Multicopper oxidase	-	-	1.7.2.1	ko:K00368	ko00910,ko01120,map00910,map01120	M00529	R00783,R00785	RC00086	ko00000,ko00001,ko00002,ko01000	-	-	-	Cu-oxidase_3
k141_5450_1	1333998.M2A_0661	1.18e-18	80.9	COG0691@1|root,COG0691@2|Bacteria,1RDFP@1224|Proteobacteria,2U71I@28211|Alphaproteobacteria,4BQB6@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	O	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA	smpB	-	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
k141_5450_2	1380394.JADL01000011_gene3885	1.24e-48	162.0	COG1573@1|root,COG1573@2|Bacteria,1MW91@1224|Proteobacteria,2TSUP@28211|Alphaproteobacteria,2JRPT@204441|Rhodospirillales	204441|Rhodospirillales	L	Uracil-DNA glycosylase	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
k141_2366_1	298386.PBPRB0593	2.45e-33	129.0	COG3391@1|root,COG3391@2|Bacteria,1R4KD@1224|Proteobacteria,1S1C1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Domain of unknown function (DUF4842)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4842
k141_514_1	1121937.AUHJ01000008_gene2070	5.4e-49	173.0	COG0209@1|root,COG1372@1|root,COG0209@2|Bacteria,COG1372@2|Bacteria,1MUJ8@1224|Proteobacteria,1RQUR@1236|Gammaproteobacteria,469SP@72275|Alteromonadaceae	1236|Gammaproteobacteria	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	nrdZ	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Intein_splicing,LAGLIDADG_3,Ribonuc_red_lgC,Ribonuc_red_lgN
k141_514_2	1205753.A989_13759	6.58e-11	62.8	COG0209@1|root,COG0209@2|Bacteria,1P4EH@1224|Proteobacteria,1RP1A@1236|Gammaproteobacteria,1X3FG@135614|Xanthomonadales	135614|Xanthomonadales	F	COG0209 Ribonucleotide reductase, alpha subunit	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_8486_1	10228.TriadP63048	2.33e-18	77.8	28JJ8@1|root,2QRYE@2759|Eukaryota	2759|Eukaryota	C	chlorophyll binding	psaB	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009534,GO:0009535,GO:0009536,GO:0009579,GO:0016020,GO:0016168,GO:0031976,GO:0031984,GO:0034357,GO:0042651,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044436,GO:0044444,GO:0044446,GO:0044464,GO:0046906,GO:0048037,GO:0055035,GO:0097159,GO:1901363	-	ko:K02690	ko00195,ko01100,map00195,map01100	M00163	-	-	ko00000,ko00001,ko00002,ko00194	-	-	-	PsaA_PsaB
k141_8486_2	159749.E7BWJ3	1.61e-193	555.0	28JJ8@1|root,2QRYE@2759|Eukaryota	2759|Eukaryota	C	chlorophyll binding	psaA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009534,GO:0009535,GO:0009536,GO:0009579,GO:0016020,GO:0031976,GO:0031984,GO:0034357,GO:0042651,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044436,GO:0044444,GO:0044446,GO:0044464,GO:0055035	-	ko:K02689,ko:K02690	ko00195,ko01100,map00195,map01100	M00163	-	-	ko00000,ko00001,ko00002,ko00194	-	-	-	PsaA_PsaB
k141_9082_1	391595.RLO149_c040770	4.09e-63	210.0	COG3119@1|root,COG3119@2|Bacteria,1MUJH@1224|Proteobacteria,2TSB8@28211|Alphaproteobacteria,2P4EE@2433|Roseobacter	28211|Alphaproteobacteria	P	C-terminal region of aryl-sulfatase	aslA	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	DUF4994,Sulfatase,Sulfatase_C
k141_4219_1	436308.Nmar_1713	8.1e-94	278.0	COG1136@1|root,arCOG00922@2157|Archaea,41T2R@651137|Thaumarchaeota	651137|Thaumarchaeota	E	ABC-type antimicrobial peptide transport system, ATPase component	-	-	-	ko:K02003,ko:K09810	ko02010,map02010	M00255,M00258	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1,3.A.1.125	-	-	ABC_tran
k141_7856_1	1415778.JQMM01000001_gene1067	3.42e-145	429.0	COG1884@1|root,COG1884@2|Bacteria,1MUXX@1224|Proteobacteria,1RSHX@1236|Gammaproteobacteria,1J4JG@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	I	COG1884 Methylmalonyl-CoA mutase, N-terminal domain subunit	scpA	GO:0003674,GO:0003824,GO:0004494,GO:0005488,GO:0008144,GO:0016853,GO:0016866,GO:0019842,GO:0031419,GO:0036094,GO:0046906,GO:0048037,GO:0097159,GO:1901363	5.4.99.2	ko:K01847,ko:K01848	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	iECO111_1330.ECO111_3653,iECO26_1355.ECO26_4004	B12-binding,MM_CoA_mutase
k141_9083_1	1380600.AUYN01000001_gene2473	2.9e-111	328.0	COG1215@1|root,COG1215@2|Bacteria,4PMAY@976|Bacteroidetes,1IJPZ@117743|Flavobacteriia	976|Bacteroidetes	M	glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
k141_2985_1	2850.Phatr39483	0.000711	49.7	2D4B4@1|root,2SUIV@2759|Eukaryota,2XHU1@2836|Bacillariophyta	2836|Bacillariophyta	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_7286_1	1209072.ALBT01000038_gene2447	2.54e-13	75.5	COG4251@1|root,COG4251@2|Bacteria,1NSQ1@1224|Proteobacteria,1RYEF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Histidine kinase	bphP	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HWE_HK,HisKA,PAS_2,PHY,Response_reg
k141_1093_1	1123070.KB899249_gene297	1.83e-49	172.0	COG1538@1|root,COG1538@2|Bacteria,46YW4@74201|Verrucomicrobia,2IU6N@203494|Verrucomicrobiae	203494|Verrucomicrobiae	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
k141_480_1	1333998.M2A_2622	1.25e-70	232.0	COG1154@1|root,COG1154@2|Bacteria,1MUSJ@1224|Proteobacteria,2TRDD@28211|Alphaproteobacteria,4BP5K@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	H	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)	dxs	-	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	-	DXP_synthase_N,Transket_pyr,Transketolase_C
k141_1717_1	159749.E7BWC3	2.07e-50	161.0	COG0199@1|root,KOG1741@2759|Eukaryota,2XGBA@2836|Bacillariophyta	2836|Bacillariophyta	J	Binds 16S rRNA, required for the assembly of 30S particles	-	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009507,GO:0009536,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02954	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S14
k141_1094_1	1502850.FG91_01681	6.54e-70	227.0	COG0204@1|root,COG0560@1|root,COG0204@2|Bacteria,COG0560@2|Bacteria,1MY51@1224|Proteobacteria,2UI5H@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	Phosphate acyltransferases	-	-	2.3.1.51,3.1.3.3	ko:K15781	-	-	-	-	ko00000,ko01000	-	-	-	Acyltransferase,HAD
k141_6648_1	1437882.AZRU01000059_gene4148	2.1e-75	236.0	COG0189@1|root,COG0189@2|Bacteria,1MVUA@1224|Proteobacteria,1RMU0@1236|Gammaproteobacteria,1YDNY@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	H	Belongs to the prokaryotic GSH synthase family	gshB	GO:0000287,GO:0003674,GO:0003824,GO:0004363,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006518,GO:0006575,GO:0006749,GO:0006750,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0019184,GO:0034641,GO:0042398,GO:0043043,GO:0043167,GO:0043169,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0051186,GO:0051188,GO:0071704,GO:1901564,GO:1901566,GO:1901576	6.3.2.3	ko:K01920	ko00270,ko00480,ko01100,map00270,map00480,map01100	M00118	R00497,R10994	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	iECED1_1282.ECED1_3410,iECP_1309.ECP_2941	GSH-S_ATP,GSH-S_N
k141_4187_1	187272.Mlg_0308	4.34e-41	151.0	COG1502@1|root,COG1502@2|Bacteria,1MWUW@1224|Proteobacteria,1RPQG@1236|Gammaproteobacteria,1WXED@135613|Chromatiales	135613|Chromatiales	I	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol	-	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2,PLDc_N
k141_9709_1	234267.Acid_0105	0.000291	48.5	COG1629@1|root,COG1629@2|Bacteria,3Y2N1@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
k141_6021_1	1131269.AQVV01000028_gene45	1.22e-91	280.0	COG0535@1|root,COG0535@2|Bacteria	2|Bacteria	I	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Fer4_14,PCP_red,Radical_SAM,SPASM
k141_9053_1	631454.N177_3617	5.22e-36	130.0	COG0496@1|root,COG0496@2|Bacteria,1MVHE@1224|Proteobacteria,2TQXZ@28211|Alphaproteobacteria,1JN6V@119043|Rhodobiaceae	28211|Alphaproteobacteria	S	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates	surE	-	3.1.3.5	ko:K03787	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	SurE
k141_9053_2	272560.BPSL2600	0.000125	45.4	COG0172@1|root,COG0172@2|Bacteria,1MUJF@1224|Proteobacteria,2VHJJ@28216|Betaproteobacteria,1K2ZR@119060|Burkholderiaceae	28216|Betaproteobacteria	J	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
k141_2332_1	1238182.C882_2101	2.3e-39	136.0	COG2020@1|root,COG2020@2|Bacteria,1MWU6@1224|Proteobacteria,2TU80@28211|Alphaproteobacteria,2JU60@204441|Rhodospirillales	204441|Rhodospirillales	O	methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
k141_1096_2	1230476.C207_02929	7.31e-52	173.0	COG2801@1|root,COG2801@2|Bacteria,1MVXQ@1224|Proteobacteria,2U0FG@28211|Alphaproteobacteria,3JX5H@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	L	COG2801 Transposase and inactivated derivatives	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve,rve_2
k141_8465_1	1128421.JAGA01000002_gene77	6.7e-72	226.0	COG0016@1|root,COG0016@2|Bacteria,2NNNT@2323|unclassified Bacteria	2|Bacteria	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily	pheS	GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Phe_tRNA-synt_N,tRNA-synt_2d
k141_8465_2	1190603.AJYD01000023_gene711	4.42e-09	55.1	2CEUC@1|root,32S0I@2|Bacteria,1MZ90@1224|Proteobacteria,1SATY@1236|Gammaproteobacteria,1Y162@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_6022_1	1380600.AUYN01000007_gene3254	3.16e-111	327.0	COG0714@1|root,COG0714@2|Bacteria,4NDVZ@976|Bacteroidetes,1HWNM@117743|Flavobacteriia	976|Bacteroidetes	S	ATPase family associated with various cellular activities (AAA)	moxR	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
k141_5418_1	243090.RB154	1.15e-21	99.0	COG3386@1|root,COG3386@2|Bacteria	2|Bacteria	G	gluconolactonase activity	-	-	-	-	-	-	-	-	-	-	-	-	ASH,Cadherin,DUF11,DUF4347,DUF5122,He_PIG,Laminin_G_3,SBBP
k141_9710_2	204536.SULAZ_1727	3.08e-06	47.4	COG0100@1|root,COG0100@2|Bacteria,2G43F@200783|Aquificae	200783|Aquificae	J	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome	rpsK	GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
k141_7256_1	713586.KB900536_gene2528	5.7e-95	290.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,1RMWA@1236|Gammaproteobacteria,1WWMG@135613|Chromatiales	135613|Chromatiales	L	DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA	rhlB	-	3.6.4.13	ko:K03732	ko03018,map03018	M00394	-	-	ko00000,ko00001,ko00002,ko01000,ko03019	-	-	-	DEAD,Helicase_C
k141_9054_1	293826.Amet_4336	2.5e-24	101.0	COG1473@1|root,COG1473@2|Bacteria,1TPD7@1239|Firmicutes,248AH@186801|Clostridia,36DRG@31979|Clostridiaceae	186801|Clostridia	E	amidohydrolase	cpsA	-	-	ko:K01436	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
k141_4807_1	1094184.KWO_0100385	1.22e-14	70.9	COG0302@1|root,COG0302@2|Bacteria,1MY3N@1224|Proteobacteria,1RMQM@1236|Gammaproteobacteria,1X3YF@135614|Xanthomonadales	135614|Xanthomonadales	F	GTP cyclohydrolase	folE	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	3.5.4.16	ko:K01495	ko00790,ko01100,map00790,map01100	M00126,M00841,M00842,M00843	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_cyclohydroI
k141_4807_2	930169.B5T_02691	2.04e-19	89.7	COG3386@1|root,COG3386@2|Bacteria,1MX7V@1224|Proteobacteria,1RMQK@1236|Gammaproteobacteria,1XJKP@135619|Oceanospirillales	135619|Oceanospirillales	G	Gluconolactonase	-	-	-	-	-	-	-	-	-	-	-	-	Str_synth
k141_6649_1	10224.XP_006826129.1	1.02e-201	605.0	COG2801@1|root,KOG0017@2759|Eukaryota,38F42@33154|Opisthokonta,3BA5H@33208|Metazoa,3CWAK@33213|Bilateria	33208|Metazoa	E	K02A2.6-like	-	-	-	-	-	-	-	-	-	-	-	-	RVT_1,SCAN,rve,zf-CCHC,zf-H2C2
k141_483_1	436308.Nmar_0320	4.98e-92	272.0	COG0063@1|root,arCOG00018@2157|Archaea,41SHM@651137|Thaumarchaeota	651137|Thaumarchaeota	G	Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX	nnrE	-	5.1.99.6	ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	YjeF_N
k141_483_2	1229909.NSED_01550	6.62e-22	89.7	arCOG00517@1|root,arCOG00517@2157|Archaea,41SHJ@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
k141_5419_1	404589.Anae109_3191	1.37e-58	198.0	COG1719@1|root,COG3829@1|root,COG1719@2|Bacteria,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,42M2E@68525|delta/epsilon subdivisions,2WKAB@28221|Deltaproteobacteria,2YWDZ@29|Myxococcales	28221|Deltaproteobacteria	K	Transcriptional regulator, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Sigma54_activat,V4R,XylR_N
k141_7257_1	1205680.CAKO01000007_gene4425	1.64e-81	254.0	COG0436@1|root,COG0436@2|Bacteria,1MWS8@1224|Proteobacteria,2TRE3@28211|Alphaproteobacteria,2JPZZ@204441|Rhodospirillales	204441|Rhodospirillales	E	Aminotransferase	-	-	-	ko:K14261	-	-	-	-	ko00000,ko01000,ko01007	-	-	-	Aminotran_1_2
k141_4808_2	1541065.JRFE01000059_gene5687	4.22e-08	55.1	COG0399@1|root,COG0399@2|Bacteria,1GJK5@1117|Cyanobacteria,3VKFF@52604|Pleurocapsales	1117|Cyanobacteria	J	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
k141_2335_1	1288298.rosmuc_00732	1.32e-91	280.0	COG1109@1|root,COG1109@2|Bacteria,1MU24@1224|Proteobacteria,2TQWH@28211|Alphaproteobacteria,46NKP@74030|Roseovarius	28211|Alphaproteobacteria	G	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate	glmM	-	5.4.2.10	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	-	R02060	RC00408	ko00000,ko00001,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
k141_6650_1	380358.XALC_1139	3.27e-58	198.0	COG0415@1|root,COG0415@2|Bacteria,1MV9Y@1224|Proteobacteria,1RNGJ@1236|Gammaproteobacteria,1X3VI@135614|Xanthomonadales	135614|Xanthomonadales	L	Belongs to the DNA photolyase family	phr	-	4.1.99.3	ko:K01669	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_photolyase,FAD_binding_7
k141_5420_1	2342.SOPEG_3100	1.59e-11	69.3	COG1520@1|root,COG1520@2|Bacteria,1MXIJ@1224|Proteobacteria,1RN4V@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamB	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0008104,GO:0008150,GO:0008152,GO:0009279,GO:0009987,GO:0016020,GO:0016043,GO:0016491,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031224,GO:0031230,GO:0031241,GO:0031246,GO:0031975,GO:0032991,GO:0033036,GO:0034613,GO:0042802,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044425,GO:0044462,GO:0044464,GO:0045184,GO:0045229,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0055114,GO:0061024,GO:0070727,GO:0071709,GO:0071840,GO:0071944,GO:0072657,GO:0090150,GO:0098552,GO:0098796,GO:1990063	-	ko:K17713	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	PQQ_2,PQQ_3
k141_1721_2	697282.Mettu_1569	2e-38	133.0	COG2905@1|root,COG2905@2|Bacteria,1MZGY@1224|Proteobacteria,1S86K@1236|Gammaproteobacteria,1XF65@135618|Methylococcales	135618|Methylococcales	T	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
k141_6025_1	1187851.A33M_4208	2.44e-69	226.0	COG0493@1|root,COG0493@2|Bacteria,1MU2H@1224|Proteobacteria,2TSE2@28211|Alphaproteobacteria,3FCY5@34008|Rhodovulum	28211|Alphaproteobacteria	E	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster	-	-	-	-	-	-	-	-	-	-	-	-	DHODB_Fe-S_bind,Fer4_20,Pyr_redox_2
k141_485_2	491205.JARQ01000007_gene2991	5e-46	157.0	COG1741@1|root,COG1741@2|Bacteria,4NGJ5@976|Bacteroidetes,1HYY2@117743|Flavobacteriia,3ZPXV@59732|Chryseobacterium	976|Bacteroidetes	T	Belongs to the pirin family	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin
k141_9057_1	7668.SPU_025648-tr	3.38e-07	53.9	KOG4585@1|root,KOG4585@2759|Eukaryota,3A47U@33154|Opisthokonta,3BQSS@33208|Metazoa,3D76C@33213|Bilateria	33208|Metazoa	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_4
k141_4193_1	1173264.KI913949_gene2973	3.53e-08	52.4	COG0268@1|root,COG0268@2|Bacteria,1G7PV@1117|Cyanobacteria,1HC92@1150|Oscillatoriales	1117|Cyanobacteria	J	Binds directly to 16S ribosomal RNA	rpsT	-	-	ko:K02968	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S20p
k141_7259_1	1027273.GZ77_08065	2.87e-26	114.0	COG4584@1|root,COG4584@2|Bacteria,1MU2G@1224|Proteobacteria,1RQA2@1236|Gammaproteobacteria,1XHVQ@135619|Oceanospirillales	135619|Oceanospirillales	L	Transposase and inactivated derivatives COG4584	-	-	-	-	-	-	-	-	-	-	-	-	HTH_24,rve
k141_7827_1	1131269.AQVV01000011_gene2533	5.46e-87	268.0	COG0148@1|root,COG0148@2|Bacteria	2|Bacteria	G	phosphopyruvate hydratase activity	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
k141_1100_1	1245469.S58_14770	4.6e-69	218.0	2C96H@1|root,2Z7Q6@2|Bacteria,1PQG4@1224|Proteobacteria,2U4JC@28211|Alphaproteobacteria,3K2K8@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Sulfotransferase domain	-	-	-	ko:K13472	ko04626,map04626	-	-	-	ko00000,ko00001	-	-	-	Sulfotransfer_3
k141_1722_1	1123247.AUIJ01000014_gene1176	4.73e-29	109.0	COG1309@1|root,COG1309@2|Bacteria,1R7JI@1224|Proteobacteria,2U0P5@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	transcriptional regulator	kstR2	-	-	-	-	-	-	-	-	-	-	-	TetR_C_4,TetR_N
k141_1722_2	1415756.JQMY01000001_gene1970	3.23e-83	253.0	COG1741@1|root,COG1741@2|Bacteria,1MWIP@1224|Proteobacteria,2TRHR@28211|Alphaproteobacteria,2PDT9@252301|Oceanicola	28211|Alphaproteobacteria	S	Pirin	yhhW	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin,Pirin_C
k141_9795_1	1250232.JQNJ01000001_gene1753	8.99e-63	219.0	COG1361@1|root,COG2373@1|root,COG2911@1|root,COG3209@1|root,COG3291@1|root,COG5492@1|root,COG1361@2|Bacteria,COG2373@2|Bacteria,COG2911@2|Bacteria,COG3209@2|Bacteria,COG3291@2|Bacteria,COG5492@2|Bacteria	2|Bacteria	N	domain, Protein	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	CHU_C,DUF11
k141_3628_1	2850.Phatrdraft1240	3.74e-16	84.3	COG2801@1|root,KOG0017@2759|Eukaryota,2XEGG@2836|Bacillariophyta	2836|Bacillariophyta	L	transposition, RNA-mediated	-	-	-	-	-	-	-	-	-	-	-	-	RVT_2,gag_pre-integrs,rve,zf-CCHC
k141_5517_1	215803.DB30_0610	2.84e-12	71.6	COG2854@1|root,COG2854@2|Bacteria	2|Bacteria	Q	intermembrane phospholipid transfer	ttg2D	-	-	ko:K07323	ko02010,map02010	M00210	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27.3	-	-	MlaC
k141_8558_1	400668.Mmwyl1_0248	2.76e-61	201.0	COG2379@1|root,COG2379@2|Bacteria,1MVIK@1224|Proteobacteria,1RPKA@1236|Gammaproteobacteria,1XN7P@135619|Oceanospirillales	135619|Oceanospirillales	G	Domain of unknown function (DUF4147)	-	-	2.7.1.165	ko:K11529	ko00030,ko00260,ko00561,ko00630,ko00680,ko01100,ko01120,ko01130,ko01200,map00030,map00260,map00561,map00630,map00680,map01100,map01120,map01130,map01200	M00346	R08572	RC00002,RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF4147,MOFRL
k141_6742_1	936136.ARRT01000005_gene199	2.57e-84	263.0	COG1861@1|root,COG1861@2|Bacteria,1QU5J@1224|Proteobacteria,2U0ZH@28211|Alphaproteobacteria,4BJ1H@82115|Rhizobiaceae	28211|Alphaproteobacteria	L	Transposase DDE domain group 1	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_4
k141_4280_1	159749.E7BWD3	5.23e-81	273.0	COG0085@1|root,KOG0214@2759|Eukaryota,2XEM3@2836|Bacillariophyta	2836|Bacillariophyta	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	-	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009536,GO:0030880,GO:0032991,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0061695,GO:1902494,GO:1990234	-	-	-	-	-	-	-	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
k141_6131_1	391589.RGAI101_1033	4.78e-69	222.0	COG0508@1|root,COG0508@2|Bacteria,1MUJD@1224|Proteobacteria,2TS5N@28211|Alphaproteobacteria,2P181@2433|Roseobacter	28211|Alphaproteobacteria	C	The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)	sucB	-	2.3.1.61	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R02570,R02571,R08549	RC00004,RC02727,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
k141_3630_1	1120956.JHZK01000027_gene1173	1.34e-67	223.0	COG4231@1|root,COG4231@2|Bacteria,1MUKS@1224|Proteobacteria,2TSHH@28211|Alphaproteobacteria,1JQ6P@119043|Rhodobiaceae	28211|Alphaproteobacteria	C	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain	iorA	-	1.2.7.8	ko:K00179	-	-	-	-	br01601,ko00000,ko01000	-	-	-	Fer4_10,POR_N,TPP_enzyme_C
k141_2434_2	1089439.KB902267_gene5	2.92e-17	75.5	arCOG05874@1|root,2ZJ01@2|Bacteria,1N8VY@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_6744_1	487796.Flav2ADRAFT_0929	9.91e-29	111.0	2FIGN@1|root,34A8Q@2|Bacteria,4P60B@976|Bacteroidetes,1IAC8@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_4897_1	367336.OM2255_12557	2.68e-61	210.0	COG0308@1|root,COG0308@2|Bacteria,1MUCI@1224|Proteobacteria,2TRUM@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	aminopeptidase N	pepN	GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0008270,GO:0016020,GO:0016787,GO:0019538,GO:0033218,GO:0042277,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0070006,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564	3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	DUF3458,DUF3458_C,Peptidase_M1
k141_8559_1	1121935.AQXX01000025_gene1583	2.19e-08	52.4	2EMPC@1|root,33FBT@2|Bacteria,1QNQV@1224|Proteobacteria,1SI44@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_1196_1	765910.MARPU_16370	5.7e-21	89.7	COG3293@1|root,COG3293@2|Bacteria,1RIUE@1224|Proteobacteria,1S88J@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	COG3293 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_2
k141_9799_1	1346330.M472_10795	1.18e-10	68.9	COG1361@1|root,COG2885@1|root,COG3209@1|root,COG3210@1|root,COG4719@1|root,COG1361@2|Bacteria,COG2885@2|Bacteria,COG3209@2|Bacteria,COG3210@2|Bacteria,COG4719@2|Bacteria,4PKBQ@976|Bacteroidetes,1J10X@117747|Sphingobacteriia	976|Bacteroidetes	MU	Domain of unknown function DUF11	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,DUF11,SprB
k141_4899_1	1049564.TevJSym_bb00050	2.7e-45	164.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,1NBSJ@1224|Proteobacteria,1S0WV@1236|Gammaproteobacteria,1J5KF@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases	korA	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR,POR_N
k141_581_1	376733.IT41_17935	2.56e-53	175.0	COG2801@1|root,COG2963@1|root,COG2801@2|Bacteria,COG2963@2|Bacteria,1PBHA@1224|Proteobacteria,2TRQF@28211|Alphaproteobacteria,2PVTX@265|Paracoccus	28211|Alphaproteobacteria	L	Integrase core domain	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_32,rve,rve_3
k141_6134_1	290398.Csal_0597	5.68e-85	257.0	COG0500@1|root,COG2226@2|Bacteria,1MX8I@1224|Proteobacteria,1RMAU@1236|Gammaproteobacteria,1XI77@135619|Oceanospirillales	135619|Oceanospirillales	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2)	ubiE	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
k141_3410_1	981384.AEYW01000022_gene3774	3.6e-62	209.0	COG0457@1|root,COG2114@1|root,COG5616@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG5616@2|Bacteria,1P4BI@1224|Proteobacteria,2TUTZ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc,Response_reg
k141_4669_1	187272.Mlg_0982	4.1e-86	275.0	COG1298@1|root,COG1298@2|Bacteria,1MUF3@1224|Proteobacteria,1RMSM@1236|Gammaproteobacteria,1WVWU@135613|Chromatiales	135613|Chromatiales	N	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin	flhA	-	-	ko:K02400	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	FHIPEP
k141_8925_1	1380367.JIBC01000006_gene640	2.84e-99	307.0	COG0021@1|root,COG0021@2|Bacteria,1MUEY@1224|Proteobacteria,2TQUX@28211|Alphaproteobacteria,3ZWST@60136|Sulfitobacter	28211|Alphaproteobacteria	G	Belongs to the transketolase family	tktA	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
k141_6517_1	78898.MVEG_07943T0	4.92e-126	375.0	COG0129@1|root,KOG2448@2759|Eukaryota,38F28@33154|Opisthokonta,3NUBR@4751|Fungi,1GS3V@112252|Fungi incertae sedis	4751|Fungi	E	Dehydratase family	ILV3	GO:0003674,GO:0003824,GO:0004160,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006082,GO:0006520,GO:0006549,GO:0006551,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0019752,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
k141_5284_1	313590.MED134_05254	2.56e-90	289.0	COG0178@1|root,COG0178@2|Bacteria,4NEHM@976|Bacteroidetes,1HXI7@117743|Flavobacteriia,37ESK@326319|Dokdonia	976|Bacteroidetes	L	ABC transporter	uvrA1	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	AAA_21,ABC_tran
k141_9581_1	1121875.KB907547_gene2914	1.62e-44	161.0	COG2172@1|root,COG2208@1|root,COG2172@2|Bacteria,COG2208@2|Bacteria,4NMVU@976|Bacteroidetes	976|Bacteroidetes	KT	Histidine kinase-like ATPase domain	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	HATPase_c_2,SpoIIE
k141_8325_1	688270.Celal_1200	7.56e-127	391.0	COG0060@1|root,COG0060@2|Bacteria,4NEYT@976|Bacteroidetes,1HX3Y@117743|Flavobacteriia,1F851@104264|Cellulophaga	976|Bacteroidetes	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1
k141_1580_1	765911.Thivi_0612	6.68e-49	162.0	COG0854@1|root,COG0854@2|Bacteria,1MU9W@1224|Proteobacteria,1RMS5@1236|Gammaproteobacteria,1WXFG@135613|Chromatiales	135613|Chromatiales	H	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate	pdxJ	-	2.6.99.2	ko:K03474	ko00750,ko01100,map00750,map01100	M00124	R05838	RC01476	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxJ
k141_964_1	1116375.VEJY3_04050	8.51e-195	550.0	COG1680@1|root,COG1680@2|Bacteria,1MY01@1224|Proteobacteria,1RNUI@1236|Gammaproteobacteria,1XZIB@135623|Vibrionales	135623|Vibrionales	V	Beta-lactamase	-	-	3.5.2.6	ko:K01467	ko01501,ko02020,map01501,map02020	M00628	R06363	RC01499	ko00000,ko00001,ko00002,ko01000	-	-	-	Beta-lactamase
k141_964_2	754477.Q7C_285	1.8e-08	56.2	COG0585@1|root,COG0585@2|Bacteria,1MXHD@1224|Proteobacteria,1RPRF@1236|Gammaproteobacteria,460GW@72273|Thiotrichales	72273|Thiotrichales	J	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs	truD	-	5.4.99.27	ko:K06176	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruD
k141_6518_1	1123400.KB904769_gene2854	2.99e-46	154.0	COG1981@1|root,COG1981@2|Bacteria,1RHGS@1224|Proteobacteria,1S5XY@1236|Gammaproteobacteria,460VS@72273|Thiotrichales	72273|Thiotrichales	S	PFAM Uncharacterised protein family (UPF0093)	-	-	-	ko:K08973	-	-	-	-	ko00000	-	-	-	UPF0093
k141_5361_2	519989.ECTPHS_12622	2.43e-20	88.2	COG3087@1|root,COG3087@2|Bacteria,1RCC0@1224|Proteobacteria,1SWTF@1236|Gammaproteobacteria,1WZTX@135613|Chromatiales	135613|Chromatiales	D	Sporulation related domain	-	-	-	-	-	-	-	-	-	-	-	-	SPOR
k141_8994_1	1437882.AZRU01000010_gene542	9.22e-30	108.0	COG2331@1|root,COG2331@2|Bacteria,1N6Q9@1224|Proteobacteria,1SCJS@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Regulatory protein, FmdB family	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
k141_8994_2	1046724.KB889893_gene3127	3.27e-18	83.2	COG0173@1|root,COG0173@2|Bacteria,1MUXB@1224|Proteobacteria,1RNMI@1236|Gammaproteobacteria,46435@72275|Alteromonadaceae	1236|Gammaproteobacteria	J	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)	aspS	GO:0003674,GO:0003824,GO:0004812,GO:0004815,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006422,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	iSFV_1184.SFV_1868	GAD,tRNA-synt_2,tRNA_anti-codon
k141_1033_1	1122134.KB893651_gene2046	3.65e-16	80.1	COG1506@1|root,COG1506@2|Bacteria,1P6E1@1224|Proteobacteria,1RPRK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	peptidase	dpp4	-	3.4.14.5	ko:K01278	ko04974,map04974	-	-	-	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	-	-	-	DPPIV_N,Peptidase_S9
k141_1033_2	290633.GOX0892	8.93e-25	103.0	COG0178@1|root,COG0178@2|Bacteria,1MW0W@1224|Proteobacteria,2TQK9@28211|Alphaproteobacteria,2JP8R@204441|Rhodospirillales	204441|Rhodospirillales	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
k141_4125_1	1229909.NSED_00425	2e-90	281.0	COG0642@1|root,arCOG02358@2157|Archaea	2157|Archaea	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
k141_8403_1	1336803.PHEL49_2081	1.62e-74	238.0	COG5492@1|root,COG5492@2|Bacteria,4PM9P@976|Bacteroidetes,1I0RN@117743|Flavobacteriia,3VX02@52959|Polaribacter	976|Bacteroidetes	N	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_2
k141_3472_1	159749.K0RA91	2.16e-87	288.0	2D0ZX@1|root,2SG6M@2759|Eukaryota,2XFQF@2836|Bacillariophyta	2836|Bacillariophyta	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_422_1	159749.K0S4X1	6.88e-15	78.6	COG2801@1|root,KOG0017@2759|Eukaryota,2XHI8@2836|Bacillariophyta	159749.K0S4X1|-	L	transposition, RNA-mediated	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_7771_1	1122201.AUAZ01000027_gene2178	5.17e-87	281.0	COG3383@1|root,COG3383@2|Bacteria,1QTZB@1224|Proteobacteria,1T1JA@1236|Gammaproteobacteria,469S2@72275|Alteromonadaceae	1236|Gammaproteobacteria	C	NADH-ubiquinone oxidoreductase-G iron-sulfur binding region	fdhF	GO:0003674,GO:0003824,GO:0003954,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009987,GO:0015942,GO:0015944,GO:0016491,GO:0016651,GO:0016999,GO:0017144,GO:0019752,GO:0030151,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704	1.17.1.9,1.17.99.7	ko:K00123,ko:K22015	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	iECBD_1354.ECBD_3953	Fer2_4,Fer4,Fer4_7,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
k141_2890_1	1269813.ATUL01000001_gene992	2.46e-128	376.0	COG0206@1|root,COG0206@2|Bacteria,1MV2X@1224|Proteobacteria,1RPZS@1236|Gammaproteobacteria,1WXJ6@135613|Chromatiales	135613|Chromatiales	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
k141_1034_1	596320.NEIFL0001_1390	1.03e-20	87.8	COG0424@1|root,COG0424@2|Bacteria,1RH6H@1224|Proteobacteria,2VQC3@28216|Betaproteobacteria,2KR56@206351|Neisseriales	206351|Neisseriales	D	Maf-like protein	-	-	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
k141_1034_2	83406.HDN1F_06220	4.51e-33	127.0	COG1530@1|root,COG1530@2|Bacteria,1MV65@1224|Proteobacteria,1RMIW@1236|Gammaproteobacteria,1J5GF@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	COG1530 Ribonucleases G and E	rng	GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005856,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008996,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360	-	ko:K08301	-	-	-	-	ko00000,ko01000,ko03009,ko03019	-	-	-	RNase_E_G,S1
k141_1659_1	572480.Arnit_3065	3.32e-47	167.0	COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,42PNH@68525|delta/epsilon subdivisions,2YRFG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	EH	Thiamine pyrophosphate enzyme, central domain	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
k141_5363_1	391616.OA238_c24740	3.27e-50	167.0	COG2826@1|root,COG2826@2|Bacteria,1PP49@1224|Proteobacteria,2TRVA@28211|Alphaproteobacteria	1224|Proteobacteria	L	COG2826 Transposase and inactivated derivatives, IS30 family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_38,rve
k141_8404_1	998674.ATTE01000001_gene3662	3.78e-83	256.0	COG0142@1|root,COG0142@2|Bacteria,1MUK6@1224|Proteobacteria,1RPR7@1236|Gammaproteobacteria,45ZXK@72273|Thiotrichales	72273|Thiotrichales	H	Belongs to the FPP GGPP synthase family	-	-	2.5.1.90	ko:K02523	ko00900,ko01110,map00900,map01110	-	R09248	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	-	polyprenyl_synt
k141_9652_1	1150469.RSPPHO_03277	9.53e-20	85.9	COG1216@1|root,COG1216@2|Bacteria	2|Bacteria	V	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
k141_2277_1	1305735.JAFT01000005_gene598	1.34e-16	77.4	COG2264@1|root,COG2264@2|Bacteria,1MUPC@1224|Proteobacteria,2TTP3@28211|Alphaproteobacteria,2PC7J@252301|Oceanicola	28211|Alphaproteobacteria	J	Ribosomal protein L11 methyltransferase	prmA	-	-	ko:K02687	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PrmA
k141_2277_2	1354722.JQLS01000008_gene1974	1.07e-57	190.0	COG2807@1|root,COG2807@2|Bacteria,1QV77@1224|Proteobacteria,2TT90@28211|Alphaproteobacteria,46Q2P@74030|Roseovarius	28211|Alphaproteobacteria	P	COG0477 Permeases of the major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
k141_5967_1	2340.JV46_05690	3.84e-176	499.0	COG2826@1|root,COG2826@2|Bacteria,1PP49@1224|Proteobacteria,1RN7B@1236|Gammaproteobacteria,1JBRQ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	L	L COG2826 Transposase and inactivated derivatives, IS30 family	insI	GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0004803,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006310,GO:0006313,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0030983,GO:0032135,GO:0032196,GO:0032991,GO:0032993,GO:0034641,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363	-	ko:K07482	-	-	-	-	ko00000	-	-	-	HTH_38,rve
k141_1660_1	1121875.KB907548_gene1479	1.2e-60	195.0	COG0331@1|root,COG0331@2|Bacteria,4NE1D@976|Bacteroidetes,1HWU7@117743|Flavobacteriia	976|Bacteroidetes	I	malonyl coa-acyl carrier protein transacylase	fabD	-	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
k141_7203_1	3880.AES58588	4.16e-07	50.4	2CY54@1|root,2S23H@2759|Eukaryota,3896T@33090|Viridiplantae,3GY43@35493|Streptophyta,4JWBW@91835|fabids	35493|Streptophyta	S	Ribosomal protein S10p/S20e	rps10	-	-	ko:K02946	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S10
k141_8997_2	765914.ThisiDRAFT_1370	7.15e-45	155.0	COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,1T1HN@1236|Gammaproteobacteria,1WY5A@135613|Chromatiales	135613|Chromatiales	V	pfam abc	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
k141_6591_1	748247.AZKH_p0290	2.09e-61	204.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,2VH80@28216|Betaproteobacteria,2KW5T@206389|Rhodocyclales	206389|Rhodocyclales	IQ	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
k141_6591_2	1449351.RISW2_10800	3.42e-83	263.0	COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,2TSB1@28211|Alphaproteobacteria,4KKKQ@93682|Roseivivax	28211|Alphaproteobacteria	EH	Belongs to the TPP enzyme family	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
k141_7773_1	1219045.BV98_000615	1.84e-19	92.8	COG0845@1|root,COG5569@1|root,COG0845@2|Bacteria,COG5569@2|Bacteria,1MVAS@1224|Proteobacteria,2TTGG@28211|Alphaproteobacteria,2K25T@204457|Sphingomonadales	204457|Sphingomonadales	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K07798	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4,8.A.1	-	-	CusF_Ec,HlyD_D23,HlyD_D4
k141_1036_1	886293.Sinac_7282	7.71e-76	243.0	COG0119@1|root,COG0119@2|Bacteria,2IX7Z@203682|Planctomycetes	203682|Planctomycetes	H	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)	leuA	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
k141_2892_1	1547437.LL06_23815	2.25e-37	135.0	COG0626@1|root,COG0626@2|Bacteria,1MU57@1224|Proteobacteria,2TW14@28211|Alphaproteobacteria,43MS4@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	E	Cys/Met metabolism PLP-dependent enzyme	metB	-	2.5.1.48	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017	R00999,R01288,R02508,R03217,R03260,R04944,R04945,R04946	RC00020,RC00056,RC00069,RC00420,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000	-	-	-	Cys_Met_Meta_PP
k141_2892_2	1569209.BBPH01000025_gene211	7.6e-46	157.0	COG1162@1|root,COG1162@2|Bacteria,1MUEF@1224|Proteobacteria,2TR5R@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit	rsgA	-	3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100	-	R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009	-	-	-	RsgA_GTPase
k141_2278_1	506534.Rhein_1765	6.75e-33	131.0	COG4774@1|root,COG4774@2|Bacteria,1NMCN@1224|Proteobacteria,1T3TQ@1236|Gammaproteobacteria,1X2RZ@135613|Chromatiales	135613|Chromatiales	P	TonB dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
k141_5968_1	1353276.JADR01000008_gene945	5.17e-82	258.0	COG3505@1|root,COG3505@2|Bacteria,4NFHI@976|Bacteroidetes,1HWU1@117743|Flavobacteriia	976|Bacteroidetes	U	Type IV secretory pathway	-	-	-	-	-	-	-	-	-	-	-	-	T4SS-DNA_transf,TrwB_AAD_bind
k141_7204_1	1111732.AZOD01000006_gene78	2.88e-48	171.0	COG0497@1|root,COG0497@2|Bacteria,1MUNP@1224|Proteobacteria,1RNPZ@1236|Gammaproteobacteria,1X3M2@135614|Xanthomonadales	135614|Xanthomonadales	L	May be involved in recombinational repair of damaged DNA	recN	-	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	SMC_N
k141_1661_1	2850.Phatr43482	3.21e-66	228.0	COG0639@1|root,2S28V@2759|Eukaryota,2XBQK@2836|Bacillariophyta	2836|Bacillariophyta	T	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
k141_8998_1	391593.RCCS2_12864	5.35e-104	333.0	COG0086@1|root,COG0086@2|Bacteria,1MU3M@1224|Proteobacteria,2TRHV@28211|Alphaproteobacteria,2P11Y@2433|Roseobacter	28211|Alphaproteobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03046,ko:K13797	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
k141_425_1	234621.RER_55630	8.6e-18	84.3	COG0596@1|root,COG0596@2|Bacteria	2|Bacteria	S	hydrolase activity, acting on ester bonds	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
k141_8407_1	502025.Hoch_0991	2.33e-41	147.0	COG2801@1|root,COG2801@2|Bacteria,1P5SB@1224|Proteobacteria,4313Z@68525|delta/epsilon subdivisions,2WX2K@28221|Deltaproteobacteria,2Z2QP@29|Myxococcales	28221|Deltaproteobacteria	L	Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	rve
k141_2279_1	1469613.JT55_16875	1.64e-92	276.0	COG0284@1|root,COG0284@2|Bacteria,1MW2C@1224|Proteobacteria,2TTB3@28211|Alphaproteobacteria,3FD32@34008|Rhodovulum	28211|Alphaproteobacteria	F	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)	pyrF	GO:0003674,GO:0003824,GO:0004590,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase
k141_5365_1	478741.JAFS01000002_gene786	7.46e-103	314.0	COG0517@1|root,COG1994@1|root,COG0517@2|Bacteria,COG1994@2|Bacteria,46SM2@74201|Verrucomicrobia,37GEE@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS,Peptidase_M50
k141_7775_1	1123288.SOV_1c02950	2.31e-21	97.8	COG0243@1|root,COG0243@2|Bacteria,1TPZG@1239|Firmicutes,4H4MY@909932|Negativicutes	909932|Negativicutes	C	Anaerobic dimethyl sulfoxide reductase, A subunit, DmsA YnfE	-	-	1.8.5.3	ko:K07306	ko00920,map00920	-	R09501	RC02555	ko00000,ko00001,ko01000,ko02000	5.A.3.3	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
k141_5969_1	323261.Noc_2109	2.65e-63	216.0	COG0508@1|root,COG1249@1|root,COG0508@2|Bacteria,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,1RMFF@1236|Gammaproteobacteria,1WWGK@135613|Chromatiales	135613|Chromatiales	C	Pyridine nucleotide-disulphide oxidoreductase, dimerisation	-	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding,Pyr_redox_2,Pyr_redox_dim
k141_426_1	436308.Nmar_0386	2.22e-77	232.0	COG0250@1|root,arCOG01920@2157|Archaea,41SM6@651137|Thaumarchaeota	651137|Thaumarchaeota	K	Transcription elongation factor Spt5	spt5	-	-	ko:K02601	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KOW,Spt5-NGN
k141_426_2	1229909.NSED_01865	2.08e-31	110.0	COG2443@1|root,arCOG02204@2157|Archaea,41TA4@651137|Thaumarchaeota	651137|Thaumarchaeota	U	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation	-	-	-	ko:K07342	ko03060,ko04141,ko04145,ko05110,map03060,map04141,map04145,map05110	M00401	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.7,3.A.5.8,3.A.5.9	-	-	-
k141_4750_1	247634.GPB2148_596	9.47e-32	121.0	COG2269@1|root,COG2269@2|Bacteria,1MU97@1224|Proteobacteria,1RMR9@1236|Gammaproteobacteria,1J5W0@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	Elongation factor P--(R)-beta-lysine ligase	epmA	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006430,GO:0006464,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016746,GO:0016755,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0052868,GO:0071704,GO:0071915,GO:0072580,GO:0072581,GO:0090304,GO:0140096,GO:1901360,GO:1901564,GO:1901566,GO:1901576	-	ko:K04568	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	tRNA-synt_2
k141_1039_1	1250232.JQNJ01000001_gene1509	3.4e-55	190.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,4NHS5@976|Bacteroidetes,1HZ0Y@117743|Flavobacteriia	976|Bacteroidetes	EU	peptidase	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
k141_4130_1	1250232.JQNJ01000001_gene1216	1.88e-71	218.0	COG0346@1|root,COG0346@2|Bacteria,4NNGG@976|Bacteroidetes,1I1YS@117743|Flavobacteriia	976|Bacteroidetes	E	Glyoxalase bleomycin resistance protein dioxygenase	mce	-	5.1.99.1	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R02765,R09979	RC00780,RC02739	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase_4
k141_7776_2	314230.DSM3645_25392	6.21e-21	94.7	COG2931@1|root,COG3209@1|root,COG2931@2|Bacteria,COG3209@2|Bacteria,2IYH3@203682|Planctomycetes	203682|Planctomycetes	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_5970_1	305900.GV64_09505	6.8e-43	157.0	COG0845@1|root,COG0845@2|Bacteria,1MVAS@1224|Proteobacteria,1RPBZ@1236|Gammaproteobacteria,1XIE5@135619|Oceanospirillales	135619|Oceanospirillales	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K07798	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4,8.A.1	-	-	CusF_Ec,HlyD_D23
k141_3477_1	1411123.JQNH01000001_gene170	5.09e-102	310.0	COG0493@1|root,COG0493@2|Bacteria,1MU2H@1224|Proteobacteria,2TSE2@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	glutamate synthase	gltD	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	Fer4_20,Pyr_redox_2
k141_9657_1	159749.K0RL31	6.82e-19	90.9	COG2801@1|root,KOG0017@2759|Eukaryota,2XF4I@2836|Bacillariophyta	159749.K0RL31|-	L	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_1040_1	159749.K0RTY6	3.26e-134	385.0	COG0464@1|root,KOG0730@2759|Eukaryota,2XFQN@2836|Bacillariophyta	2836|Bacillariophyta	O	ATPase family associated with various cellular activities (AAA)	cbbX	-	-	-	-	-	-	-	-	-	-	-	AAA
k141_2895_1	1089552.KI911559_gene3649	5.39e-130	382.0	COG1861@1|root,COG1861@2|Bacteria,1QU5J@1224|Proteobacteria,2U0ZH@28211|Alphaproteobacteria,2JU7J@204441|Rhodospirillales	204441|Rhodospirillales	L	DDE (Asp,Asp,Glu) domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_4
k141_429_1	1089552.KI911559_gene3317	3.16e-25	106.0	COG0111@1|root,COG0111@2|Bacteria,1MU5Z@1224|Proteobacteria,2TR0F@28211|Alphaproteobacteria,2JPYH@204441|Rhodospirillales	204441|Rhodospirillales	EH	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family	serA	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C,ACT
k141_4132_1	1122963.AUHB01000003_gene3982	6.1e-46	163.0	COG4653@1|root,COG4653@2|Bacteria,1MWU1@1224|Proteobacteria,2TSSY@28211|Alphaproteobacteria,36XN3@31993|Methylocystaceae	28211|Alphaproteobacteria	S	Phage capsid family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S78,Phage_capsid
k141_7209_1	411466.ACTODO_00001	1.73e-23	91.7	2DMHR@1|root,32RMI@2|Bacteria,2HC0U@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_1041_1	1122134.KB893650_gene1198	9.61e-64	213.0	COG0441@1|root,COG0441@2|Bacteria,1MUP2@1224|Proteobacteria,1RMYE@1236|Gammaproteobacteria,1XI6X@135619|Oceanospirillales	135619|Oceanospirillales	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	-	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD
k141_2282_1	748247.AZKH_4287	2.04e-21	92.4	COG2070@1|root,COG2070@2|Bacteria,1N52W@1224|Proteobacteria,2VJ45@28216|Betaproteobacteria,2KVWV@206389|Rhodocyclales	206389|Rhodocyclales	S	2-nitropropane dioxygenase	-	-	1.13.12.16	ko:K00459	ko00910,map00910	-	R00025	RC02541,RC02759	ko00000,ko00001,ko01000	-	-	-	NMO
k141_5369_2	935557.ATYB01000014_gene4198	4.81e-35	127.0	COG3840@1|root,COG3840@2|Bacteria,1MV78@1224|Proteobacteria,2U7TZ@28211|Alphaproteobacteria,4BM62@82115|Rhizobiaceae	28211|Alphaproteobacteria	P	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system	thiQ	-	-	ko:K02062	ko02010,map02010	M00191	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.19	-	-	ABC_tran
k141_4751_1	159749.E7BWJ7	1.61e-144	415.0	COG0583@1|root,2S17Z@2759|Eukaryota	2759|Eukaryota	K	DNA-binding transcription factor activity	rbcR	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009536,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
k141_198_1	521719.ATXQ01000002_gene2582	2.96e-58	195.0	COG0477@1|root,COG2814@2|Bacteria,1MW59@1224|Proteobacteria,1RNUU@1236|Gammaproteobacteria,1YFM4@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
k141_5747_1	1469245.JFBG01000015_gene1020	2.7e-77	241.0	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,1RM93@1236|Gammaproteobacteria,1WW4A@135613|Chromatiales	135613|Chromatiales	I	Belongs to the thiolase family	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
k141_3273_1	398720.MED217_06027	5.28e-26	110.0	2DB82@1|root,2Z7PX@2|Bacteria,4NEW5@976|Bacteroidetes,1HXZZ@117743|Flavobacteriia,2XIYG@283735|Leeuwenhoekiella	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
k141_7550_1	2850.Phatr40238	3.13e-19	86.7	290ZN@1|root,2R7V7@2759|Eukaryota,2XGZN@2836|Bacillariophyta	2836|Bacillariophyta	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_2673_1	90813.JQMT01000001_gene232	8.43e-24	91.3	COG1841@1|root,COG1841@2|Bacteria,1N6ZE@1224|Proteobacteria,1SC8N@1236|Gammaproteobacteria,4617P@72273|Thiotrichales	72273|Thiotrichales	J	Ribosomal protein L30	rpmD	-	-	ko:K02907	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L30
k141_2673_2	314278.NB231_08002	1.22e-44	150.0	COG0200@1|root,COG0200@2|Bacteria,1RDC8@1224|Proteobacteria,1S3P6@1236|Gammaproteobacteria,1WYR5@135613|Chromatiales	135613|Chromatiales	J	binds to the 23S rRNA	rplO	-	-	ko:K02876	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27A
k141_7642_1	1122599.AUGR01000022_gene1626	9.48e-52	166.0	COG1432@1|root,COG1432@2|Bacteria,1MUAE@1224|Proteobacteria,1S47Z@1236|Gammaproteobacteria,1XJQI@135619|Oceanospirillales	135619|Oceanospirillales	S	nuclease	-	-	-	-	-	-	-	-	-	-	-	-	NYN
k141_7642_2	511.JT27_06725	5.42e-07	51.6	COG0500@1|root,COG2226@2|Bacteria,1MXDY@1224|Proteobacteria,2VJJM@28216|Betaproteobacteria	28216|Betaproteobacteria	Q	Methyltransferase domain	-	-	2.1.1.187	ko:K00563	-	-	R07233	RC00003	ko00000,ko01000,ko03009	-	-	-	Methyltransf_11,Methyltransf_25
k141_5229_1	1123228.AUIH01000018_gene3535	4.61e-85	262.0	COG0686@1|root,COG0686@2|Bacteria,1QTX1@1224|Proteobacteria,1T1JB@1236|Gammaproteobacteria,1XI6J@135619|Oceanospirillales	135619|Oceanospirillales	E	Belongs to the AlaDH PNT family	ald	-	1.4.1.1	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	-	R00396	RC00008	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
k141_295_1	1123355.JHYO01000027_gene2041	4.61e-19	91.7	COG1639@1|root,COG2197@1|root,COG1639@2|Bacteria,COG2197@2|Bacteria,1R6YN@1224|Proteobacteria,2U3FG@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	HDOD,Response_reg
k141_3361_1	1205680.CAKO01000029_gene5075	7.15e-45	158.0	COG4799@1|root,COG4799@2|Bacteria,1MVAX@1224|Proteobacteria,2TRI1@28211|Alphaproteobacteria,2JQVU@204441|Rhodospirillales	204441|Rhodospirillales	I	COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)	-	-	2.1.3.15,6.4.1.3	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	M00373,M00741	R01859	RC00097,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
k141_3361_2	999550.KI421507_gene2054	5.44e-41	150.0	COG4770@1|root,COG4770@2|Bacteria,1P6RE@1224|Proteobacteria,2TRC2@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	Acetyl propionyl-CoA carboxylase alpha subunit	pccA	-	6.4.1.3	ko:K01965	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	M00373,M00741	R01859	RC00097,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2
k141_912_1	404589.Anae109_1293	1.18e-45	162.0	COG0649@1|root,COG0649@2|Bacteria,1MVIN@1224|Proteobacteria,42M9G@68525|delta/epsilon subdivisions,2WIS7@28221|Deltaproteobacteria,2YU4Q@29|Myxococcales	28221|Deltaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0016020,GO:0044424,GO:0044464,GO:0071944	1.6.5.3	ko:K00333,ko:K13378	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa,Complex1_49kDa
k141_6468_1	1123256.KB907926_gene845	1.26e-35	131.0	COG0631@1|root,COG0631@2|Bacteria,1R7UF@1224|Proteobacteria,1RQUV@1236|Gammaproteobacteria,1X4AA@135614|Xanthomonadales	135614|Xanthomonadales	T	phosphatase	-	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C_2
k141_9544_1	1353537.TP2_16485	1.01e-34	128.0	COG0725@1|root,COG0725@2|Bacteria,1PA2T@1224|Proteobacteria,2U1JI@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	Extracellular solute-binding protein	-	-	5.3.3.7	ko:K02020,ko:K22003	ko00660,ko02010,map00660,map02010	M00189	R02244	RC00668	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.8	-	-	SBP_bac_11
k141_7075_2	864069.MicloDRAFT_00005790	4.61e-12	63.2	COG2801@1|root,COG2801@2|Bacteria,1N4JW@1224|Proteobacteria,2UEHC@28211|Alphaproteobacteria,1JZ63@119045|Methylobacteriaceae	28211|Alphaproteobacteria	L	HTH-like domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_21
k141_7075_3	1288826.MSNKSG1_13832	1.46e-20	85.5	COG2963@1|root,COG2963@2|Bacteria,1N28U@1224|Proteobacteria,1S9BK@1236|Gammaproteobacteria,46B8H@72275|Alteromonadaceae	1236|Gammaproteobacteria	L	Transposase	-	-	-	ko:K07483	-	-	-	-	ko00000	-	-	-	HTH_Tnp_1
k141_8275_1	371731.Rsw2DRAFT_1834	3.37e-22	95.9	COG5476@1|root,COG5476@2|Bacteria,1MX4P@1224|Proteobacteria,2TS1C@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Involved in peptidolytic degradation of cyclic heptapeptide hepatotoxin microcystin (MC)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1485,MlrC_C
k141_8275_2	207954.MED92_09471	4.88e-46	151.0	COG1607@1|root,COG1607@2|Bacteria,1MZAZ@1224|Proteobacteria,1SA9N@1236|Gammaproteobacteria,1XKRU@135619|Oceanospirillales	135619|Oceanospirillales	I	hydrolase	-	-	-	ko:K10806	ko01040,map01040	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	4HBT
k141_3994_2	1009858.BUMPG002_CDS00074	2.01e-13	66.2	COG0048@1|root,COG0048@2|Bacteria,1RCWY@1224|Proteobacteria,1S3WB@1236|Gammaproteobacteria,37DA6@32199|Buchnera	1236|Gammaproteobacteria	J	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit	rpsL	GO:0000372,GO:0000375,GO:0000376,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008380,GO:0009058,GO:0009059,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010604,GO:0010628,GO:0015935,GO:0016070,GO:0019219,GO:0019222,GO:0019538,GO:0019843,GO:0022626,GO:0022627,GO:0031323,GO:0031325,GO:0032991,GO:0033120,GO:0034336,GO:0034337,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043484,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045935,GO:0046483,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990145,GO:1990904	-	ko:K02950	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosom_S12_S23
k141_2763_1	903818.KI912269_gene491	2.71e-55	193.0	COG0438@1|root,COG0438@2|Bacteria,3Y68X@57723|Acidobacteria	57723|Acidobacteria	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
k141_7645_1	502025.Hoch_5836	9.26e-36	137.0	COG2355@1|root,COG2355@2|Bacteria,1MWEW@1224|Proteobacteria,42NXB@68525|delta/epsilon subdivisions,2WMBF@28221|Deltaproteobacteria,2YXC1@29|Myxococcales	28221|Deltaproteobacteria	E	Membrane dipeptidase (Peptidase family M19)	-	-	3.4.13.19	ko:K01273	-	-	-	-	ko00000,ko00537,ko01000,ko01002,ko04147	-	-	-	Peptidase_M19
k141_7076_1	105420.BBPO01000047_gene1665	3.18e-31	125.0	COG0515@1|root,COG0515@2|Bacteria,2GMPZ@201174|Actinobacteria,2NNBK@228398|Streptacidiphilus	201174|Actinobacteria	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
k141_6470_1	396588.Tgr7_0714	3.88e-90	288.0	COG0308@1|root,COG0308@2|Bacteria,1MUCI@1224|Proteobacteria,1RMA7@1236|Gammaproteobacteria,1WWVT@135613|Chromatiales	135613|Chromatiales	E	PFAM peptidase M1, membrane alanine aminopeptidase	pepN	-	3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	DUF3458,DUF3458_C,Peptidase_M1
k141_5844_1	218284.CCDN010000008_gene4139	9.56e-33	126.0	COG3547@1|root,COG3547@2|Bacteria,1V427@1239|Firmicutes,4HGY6@91061|Bacilli,1ZERT@1386|Bacillus	91061|Bacilli	L	PFAM transposase IS116 IS110 IS902 family	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k141_8276_1	1150469.RSPPHO_02659	9.26e-45	158.0	COG0773@1|root,COG0773@2|Bacteria,1MV68@1224|Proteobacteria,2TRT0@28211|Alphaproteobacteria,2JQAK@204441|Rhodospirillales	204441|Rhodospirillales	M	Belongs to the MurCDEF family	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
k141_8276_2	272943.RSP_2107	2.01e-12	68.2	COG0707@1|root,COG0707@2|Bacteria,1MVIB@1224|Proteobacteria,2TSEY@28211|Alphaproteobacteria,1FBKF@1060|Rhodobacter	28211|Alphaproteobacteria	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
k141_914_1	391626.OAN307_c03800	1.28e-69	222.0	COG2826@1|root,COG2826@2|Bacteria,1PP49@1224|Proteobacteria,2TRVA@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	COG2826 Transposase and inactivated derivatives, IS30 family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_38,rve
k141_3364_1	1354722.JQLS01000005_gene3919	5.33e-103	309.0	COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,2TQND@28211|Alphaproteobacteria,46NHC@74030|Roseovarius	28211|Alphaproteobacteria	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_3
k141_7077_1	1121921.KB898706_gene3358	0.000284	42.4	COG0712@1|root,COG0712@2|Bacteria,1MVRH@1224|Proteobacteria,1S8X2@1236|Gammaproteobacteria,2PNMJ@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	C	ATP synthase delta (OSCP) subunit	atpH	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0036442,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	iSF_1195.SF3815,iSFxv_1172.SFxv_4157,iS_1188.S3953	OSCP
k141_7077_2	998674.ATTE01000001_gene191	1.74e-64	211.0	COG0056@1|root,COG0056@2|Bacteria,1MUG7@1224|Proteobacteria,1RP4V@1236|Gammaproteobacteria,460AE@72273|Thiotrichales	72273|Thiotrichales	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
k141_915_1	864051.BurJ1DRAFT_4233	7.9e-08	56.2	COG0845@1|root,COG0845@2|Bacteria,1MXGH@1224|Proteobacteria,2VIDH@28216|Betaproteobacteria,1KIWE@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
k141_915_2	455436.DS989810_gene396	1.99e-06	50.4	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,464X3@72275|Alteromonadaceae	1236|Gammaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k141_2765_1	1190606.AJYG01000100_gene1018	1.64e-87	270.0	COG1883@1|root,COG1883@2|Bacteria,1MV0G@1224|Proteobacteria,1RP3W@1236|Gammaproteobacteria,1XTU0@135623|Vibrionales	135623|Vibrionales	C	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit	oadB	-	4.1.1.3	ko:K01572	ko00620,ko01100,map00620,map01100	-	R00217	RC00040	ko00000,ko00001,ko01000,ko02000	3.B.1.1.1	-	-	OAD_beta
k141_3997_1	794903.OPIT5_02440	3.51e-64	216.0	COG0480@1|root,COG0480@2|Bacteria,46SFV@74201|Verrucomicrobia,3K7PT@414999|Opitutae	414999|Opitutae	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
k141_8887_1	378806.STAUR_1988	4.78e-141	413.0	COG1609@1|root,COG1609@2|Bacteria,1R5GE@1224|Proteobacteria,42R8F@68525|delta/epsilon subdivisions,2WMTS@28221|Deltaproteobacteria	1224|Proteobacteria	K	Rhodopirellula transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISAZ013
k141_300_1	1349785.BAUG01000045_gene2275	3.38e-30	115.0	COG0144@1|root,COG0144@2|Bacteria,4NEV7@976|Bacteroidetes,1HXH7@117743|Flavobacteriia	976|Bacteroidetes	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family	rsmB	-	2.1.1.176	ko:K03500	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F,Methyltr_RsmF_N
k141_5846_1	754476.Q7A_2094	3.54e-51	176.0	COG1173@1|root,COG1173@2|Bacteria,1MU26@1224|Proteobacteria,1RND6@1236|Gammaproteobacteria,45ZVZ@72273|Thiotrichales	72273|Thiotrichales	P	inner membrane component	-	-	-	ko:K02034,ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1
k141_5846_2	754476.Q7A_2095	2.83e-06	48.5	COG0761@1|root,COG0761@2|Bacteria,1MU7G@1224|Proteobacteria,1RMN8@1236|Gammaproteobacteria,46075@72273|Thiotrichales	72273|Thiotrichales	IM	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis	ispH	-	1.17.7.4	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05884,R08210	RC01137,RC01487	ko00000,ko00001,ko00002,ko01000	-	-	-	LYTB
k141_3366_1	1123057.P872_23320	1.66e-39	141.0	COG0524@1|root,COG0524@2|Bacteria,4NIHI@976|Bacteroidetes,47NUW@768503|Cytophagia	976|Bacteroidetes	G	Belongs to the carbohydrate kinase PfkB family	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
k141_3366_2	666509.RCA23_c09180	3.2e-12	67.4	COG2937@1|root,COG2937@2|Bacteria,1MWZ6@1224|Proteobacteria,2TSDK@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	Belongs to the GPAT DAPAT family	plsB	-	2.3.1.15	ko:K00631	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
k141_7648_1	398580.Dshi_3398	1.57e-85	254.0	COG3335@1|root,COG3335@2|Bacteria,1P76X@1224|Proteobacteria,2U16U@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3
k141_8888_1	472759.Nhal_3925	6.92e-22	95.9	COG3017@1|root,COG3017@2|Bacteria,1N02T@1224|Proteobacteria,1S91E@1236|Gammaproteobacteria,1WZK9@135613|Chromatiales	135613|Chromatiales	M	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein	lolB	-	-	ko:K02494	-	-	-	-	ko00000	-	-	-	LolB
k141_8279_1	545264.KB898758_gene2679	1.84e-59	195.0	COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,1RNV0@1236|Gammaproteobacteria,1WWAB@135613|Chromatiales	135613|Chromatiales	U	Type II secretion system	-	-	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
k141_5847_1	207954.MED92_18008	1.58e-39	146.0	COG0018@1|root,COG0018@2|Bacteria,1MU4J@1224|Proteobacteria,1RPRC@1236|Gammaproteobacteria,1XIJZ@135619|Oceanospirillales	135619|Oceanospirillales	J	Catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA	argS	-	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
k141_5236_1	375286.mma_1976	3.99e-95	288.0	COG0489@1|root,COG0489@2|Bacteria,1MU7R@1224|Proteobacteria,2VIMV@28216|Betaproteobacteria,472SB@75682|Oxalobacteraceae	28216|Betaproteobacteria	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	mrp	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	FeS_assembly_P,ParA
k141_7080_1	435908.IDSA_11385	3.66e-57	192.0	COG0577@1|root,COG0577@2|Bacteria,1QSVW@1224|Proteobacteria,1RPBM@1236|Gammaproteobacteria,2QG93@267893|Idiomarinaceae	1236|Gammaproteobacteria	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
k141_3999_1	1190606.AJYG01000006_gene2344	4.36e-48	156.0	COG0347@1|root,COG0347@2|Bacteria,1RI28@1224|Proteobacteria,1S62Z@1236|Gammaproteobacteria,1XXA8@135623|Vibrionales	135623|Vibrionales	K	Belongs to the P(II) protein family	VV0993	-	-	-	-	-	-	-	-	-	-	-	-
k141_916_1	321332.CYB_1580	2.16e-43	152.0	COG0202@1|root,COG0202@2|Bacteria,1G094@1117|Cyanobacteria,1GZAY@1129|Synechococcus	1117|Cyanobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
k141_916_2	159749.E7BWN8	2.42e-63	196.0	COG0100@1|root,KOG0408@2759|Eukaryota	2759|Eukaryota	J	rRNA binding	rps11	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009536,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	Ribosomal_S11,Ribosomal_S13
k141_916_3	197221.22293824	3.68e-39	134.0	COG0099@1|root,COG0099@2|Bacteria,1G5S9@1117|Cyanobacteria	1117|Cyanobacteria	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	rpsM	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
k141_2159_1	38654.XP_006029730.1	1.45e-21	95.1	2CXPK@1|root,2RYWI@2759|Eukaryota,3A0FF@33154|Opisthokonta,3BPTP@33208|Metazoa,3D6SN@33213|Bilateria,48FM6@7711|Chordata,49CCX@7742|Vertebrata	33208|Metazoa	S	Transposase (partial DDE domain)	-	-	2.1.1.43	ko:K11433	ko00310,map00310	-	R03875,R03938,R04866,R04867	RC00003,RC00060,RC00181,RC00496	ko00000,ko00001,ko01000,ko03036	-	-	-	DDE_3,HTH_Tnp_Tc3_2,Transposase_1
k141_4624_1	1229909.NSED_09680	1.26e-34	123.0	arCOG01806@1|root,arCOG01806@2157|Archaea,41T2B@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_4624_2	1229909.NSED_09675	8.8e-66	212.0	COG1252@1|root,arCOG01067@2157|Archaea	2157|Archaea	C	COG1252 NADH dehydrogenase, FAD-containing subunit	ndh2	-	1.6.99.3	ko:K03885	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
k141_3368_2	926562.Oweho_2327	7.62e-05	44.7	COG4783@1|root,COG4783@2|Bacteria,4PKN7@976|Bacteroidetes,1IJEQ@117743|Flavobacteriia,2PARI@246874|Cryomorphaceae	976|Bacteroidetes	S	Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
k141_4000_2	35128.Thapsdraft2073	1.09e-114	342.0	28JG1@1|root,2QRV6@2759|Eukaryota,2XEM0@2836|Bacillariophyta	2836|Bacillariophyta	P	One of the components of the core complex of photosystem II (PSII). It binds chlorophyll and helps catalyze the primary light-induced photochemical processes of PSII. PSII is a light- driven water plastoquinone oxidoreductase, using light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation	psbB	-	-	ko:K02704	ko00195,ko01100,map00195,map01100	M00161	-	-	ko00000,ko00001,ko00002,ko00194	-	-	-	PSII
k141_2767_1	4555.Si020795m	6.75e-69	223.0	COG0843@1|root,KOG4769@2759|Eukaryota,37QZZ@33090|Viridiplantae,3GEEJ@35493|Streptophyta,3KME8@4447|Liliopsida,3IAIW@38820|Poales	35493|Streptophyta	C	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B	cox1	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005746,GO:0005751,GO:0006091,GO:0006119,GO:0006123,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009060,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015672,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0016310,GO:0017144,GO:0019637,GO:0019646,GO:0019693,GO:0019866,GO:0022900,GO:0022904,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0032991,GO:0034220,GO:0034641,GO:0042773,GO:0042775,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044281,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044444,GO:0044446,GO:0044455,GO:0044464,GO:0045277,GO:0045333,GO:0046034,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0055114,GO:0070069,GO:0070469,GO:0071704,GO:0072521,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098798,GO:0098800,GO:0098803,GO:1901135,GO:1901360,GO:1901564,GO:1902600	1.9.3.1	ko:K02256	ko00190,ko01100,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map04260,map04714,map04932,map05010,map05012,map05016	M00154	-	-	ko00000,ko00001,ko00002,ko01000,ko03029	3.D.4.11,3.D.4.7,3.D.4.8	-	-	COX1
k141_2767_2	1284775.HMPREF1640_13630	1.37e-07	61.2	COG3344@1|root,COG3344@2|Bacteria,4NG38@976|Bacteroidetes,2FNYW@200643|Bacteroidia	976|Bacteroidetes	L	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	Intron_maturas2,RVT_1
k141_4785_1	1049564.TevJSym_aj00810	1.02e-103	325.0	COG0243@1|root,COG0243@2|Bacteria,1P01N@1224|Proteobacteria,1RQK9@1236|Gammaproteobacteria,1J907@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Molybdopterin oxidoreductase Fe4S4 domain	ttrA	-	1.8.5.5,1.8.5.6	ko:K08352,ko:K08357,ko:K21307	ko00920,ko01100,ko01120,ko02020,map00920,map01100,map01120,map02020	-	R10149,R10150,R11487	RC00168,RC02823,RC03109	ko00000,ko00001,ko01000,ko02000	5.A.3.10,5.A.3.5	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding,TAT_signal
k141_6001_1	1265505.ATUG01000002_gene1044	1.6e-53	182.0	COG4591@1|root,COG4591@2|Bacteria,1RBRA@1224|Proteobacteria,42R8Y@68525|delta/epsilon subdivisions,2WMXR@28221|Deltaproteobacteria,2MMUC@213118|Desulfobacterales	28221|Deltaproteobacteria	M	ABC-type transport system involved in lipoprotein release permease component	-	-	-	-	-	-	-	-	-	-	-	-	FtsX
k141_4167_1	545276.KB898729_gene1711	2.5e-71	228.0	COG0174@1|root,COG0174@2|Bacteria,1MUGQ@1224|Proteobacteria,1RMD1@1236|Gammaproteobacteria,1WVZ2@135613|Chromatiales	135613|Chromatiales	E	TIGRFAM glutamine synthetase, type I	glnA	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
k141_1700_1	388399.SSE37_06194	9.6e-26	105.0	COG0683@1|root,COG0683@2|Bacteria,1MWJ1@1224|Proteobacteria,2TT0T@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	ABC-type branched-chain amino acid transport systems, periplasmic component	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
k141_8446_1	309807.SRU_1574	2.9e-38	140.0	COG0667@1|root,COG0667@2|Bacteria,4NEDK@976|Bacteroidetes,1FJJ9@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	C	Aldo/keto reductase family	tas	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
k141_9689_2	1229172.JQFA01000004_gene1346	1.25e-40	139.0	COG0222@1|root,COG0222@2|Bacteria,1G6XE@1117|Cyanobacteria,1HB00@1150|Oscillatoriales	1117|Cyanobacteria	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation	rplL	-	-	ko:K02935	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L12,Ribosomal_L12_N
k141_6633_1	1216007.AOPM01000107_gene402	2e-31	110.0	2E4EA@1|root,32Z9I@2|Bacteria,1N7HE@1224|Proteobacteria,1SDU5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_1701_1	1002340.AFCF01000050_gene1526	2.52e-80	250.0	COG0045@1|root,COG0045@2|Bacteria,1MVCE@1224|Proteobacteria,2TRXK@28211|Alphaproteobacteria,34DRT@302485|Phaeobacter	28211|Alphaproteobacteria	F	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit	mtkA	-	6.2.1.5,6.2.1.9	ko:K01903,ko:K14067	ko00020,ko00630,ko00640,ko00660,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00630,map00640,map00660,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00346,M00374,M00620	R00405,R01256,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,Ligase_CoA
k141_8447_1	1121434.AULY01000009_gene1859	1.37e-35	139.0	COG0642@1|root,COG0642@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,42M0Y@68525|delta/epsilon subdivisions,2WJCX@28221|Deltaproteobacteria,2MH92@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	PFAM ATP-binding region ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISMED2,7TMR-DISM_7TM,CHASE,DUF3365,GAF_2,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_9,PilJ,Response_reg,dCache_1
k141_9037_1	448385.sce4236	2.28e-75	253.0	COG0060@1|root,COG0060@2|Bacteria,1MVBQ@1224|Proteobacteria,42MKB@68525|delta/epsilon subdivisions,2WJ4W@28221|Deltaproteobacteria,2YUFE@29|Myxococcales	28221|Deltaproteobacteria	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1
k141_6003_1	1499967.BAYZ01000026_gene1558	2.83e-58	197.0	COG0376@1|root,COG0376@2|Bacteria,2NQNQ@2323|unclassified Bacteria	2|Bacteria	P	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity	katG	GO:0000302,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016684,GO:0016999,GO:0017001,GO:0017144,GO:0020037,GO:0033554,GO:0034599,GO:0034614,GO:0035690,GO:0042221,GO:0042493,GO:0042542,GO:0042737,GO:0042743,GO:0042744,GO:0044237,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0046906,GO:0048037,GO:0050896,GO:0051186,GO:0051187,GO:0051716,GO:0055114,GO:0070301,GO:0070887,GO:0071236,GO:0072593,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901363,GO:1901700,GO:1901701,GO:1990748	1.11.1.21	ko:K03782	ko00360,ko00380,ko00940,ko00983,ko01100,ko01110,map00360,map00380,map00940,map00983,map01100,map01110	-	R00602,R00698,R02596,R02670,R03919,R04007,R07443,R11906	RC00034,RC00213,RC00767,RC02141	ko00000,ko00001,ko01000	-	-	-	peroxidase
k141_469_1	583355.Caka_2045	1.28e-17	92.4	COG0771@1|root,COG2911@1|root,COG2931@1|root,COG0771@2|Bacteria,COG2911@2|Bacteria,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	murD	-	3.4.21.10,6.3.2.13,6.3.2.9	ko:K01317,ko:K01925,ko:K01928,ko:K01932	ko00300,ko00471,ko00550,ko01100,map00300,map00471,map00550,map01100	-	R02783,R02788	RC00064,RC00090,RC00141	ko00000,ko00001,ko01000,ko01002,ko01011,ko04131	-	-	-	DUF1727,Mur_ligase_C,Mur_ligase_M
k141_4787_1	552396.HMPREF0863_01118	3.46e-09	59.7	COG0072@1|root,COG0072@2|Bacteria,1TP98@1239|Firmicutes,3VP34@526524|Erysipelotrichia	526524|Erysipelotrichia	J	Psort location Cytoplasmic, score	pheT	-	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
k141_2317_1	1278307.KB907042_gene2340	1.03e-59	195.0	COG3547@1|root,COG3547@2|Bacteria,1MUER@1224|Proteobacteria,1RMAQ@1236|Gammaproteobacteria,2QIHE@267894|Psychromonadaceae	1236|Gammaproteobacteria	L	PFAM transposase IS116 IS110 IS902 family protein	-	-	-	ko:K07486	-	-	-	-	ko00000	-	-	-	DEDD_Tnp_IS110,Transposase_20
k141_8515_1	1122135.KB893134_gene3411	2.49e-74	233.0	COG1131@1|root,COG1131@2|Bacteria,1MUW7@1224|Proteobacteria,2TR2Q@28211|Alphaproteobacteria	28211|Alphaproteobacteria	V	ABC transporter	yadG	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
k141_2388_1	1121875.KB907547_gene3137	5.09e-72	217.0	COG1145@1|root,COG1145@2|Bacteria	2|Bacteria	C	4fe-4S ferredoxin, iron-sulfur binding domain protein	fdx1	-	-	ko:K03522,ko:K05337	-	-	-	-	ko00000,ko04147	-	-	-	Fer4,Fer4_7
k141_3006_1	13035.Dacsa_3560	3.56e-99	301.0	COG0174@1|root,COG0174@2|Bacteria,1G3WU@1117|Cyanobacteria	1117|Cyanobacteria	E	Glutamine synthetase, catalytic domain	-	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C
k141_6702_1	631362.Thi970DRAFT_04763	6.36e-152	432.0	COG0330@1|root,COG0330@2|Bacteria,1MV7R@1224|Proteobacteria,1RMF2@1236|Gammaproteobacteria,1X0ZR@135613|Chromatiales	135613|Chromatiales	O	HflC and HflK could regulate a protease	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
k141_2389_1	488538.SAR116_0230	2.19e-21	89.4	COG0625@1|root,COG0625@2|Bacteria,1RD2G@1224|Proteobacteria,2U7CB@28211|Alphaproteobacteria,4BS4I@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	O	Glutathione S-transferase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	GST_C,GST_C_2,GST_N_3
k141_2389_2	391593.RCCS2_09274	7.8e-55	182.0	COG0621@1|root,COG0621@2|Bacteria,1MUCS@1224|Proteobacteria,2TRYD@28211|Alphaproteobacteria,2P13Q@2433|Roseobacter	28211|Alphaproteobacteria	J	MiaB-like tRNA modifying enzyme	mtaB	GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016782,GO:0034470,GO:0034641,GO:0034660,GO:0035596,GO:0035598,GO:0035600,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0050497,GO:0071704,GO:0090304,GO:1901360	2.8.4.5	ko:K18707	-	-	R10649	RC00003,RC03221	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,UPF0004
k141_6084_1	697282.Mettu_2523	6.82e-94	299.0	COG0525@1|root,COG0525@2|Bacteria,1MV7B@1224|Proteobacteria,1RNEB@1236|Gammaproteobacteria,1XEJP@135618|Methylococcales	135618|Methylococcales	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	-	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
k141_539_1	985255.APHJ01000027_gene846	7.23e-68	225.0	COG2866@1|root,COG2866@2|Bacteria,4NF5T@976|Bacteroidetes,1HYNG@117743|Flavobacteriia,2P5SY@244698|Gillisia	976|Bacteroidetes	E	Zinc carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
k141_9106_2	159749.K0T1H7	3.98e-05	45.4	COG2801@1|root,KOG0017@2759|Eukaryota,2XEGY@2836|Bacillariophyta	2836|Bacillariophyta	L	transposition, RNA-mediated	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_1153_1	765698.Mesci_2630	1.01e-120	355.0	COG2072@1|root,COG2072@2|Bacteria,1MWPJ@1224|Proteobacteria,2TSQA@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	Flavoprotein involved in K transport	-	-	-	ko:K07222	-	-	-	-	ko00000	-	-	-	Pyr_redox_3
k141_1770_1	349521.HCH_00020	1.23e-13	71.2	COG0241@1|root,COG0241@2|Bacteria,1RDGR@1224|Proteobacteria,1S3UD@1236|Gammaproteobacteria,1XJQG@135619|Oceanospirillales	135619|Oceanospirillales	E	D,D-heptose 1,7-bisphosphate phosphatase	gmhB	-	3.1.3.82,3.1.3.83	ko:K03273	ko00540,ko01100,map00540,map01100	M00064	R05647,R09771	RC00017	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hydrolase_like
k141_1770_2	1397528.Q671_16080	5.03e-06	47.8	COG0751@1|root,COG0751@2|Bacteria,1MV2F@1224|Proteobacteria,1RNR3@1236|Gammaproteobacteria,1XH7W@135619|Oceanospirillales	135619|Oceanospirillales	J	Glycyl-tRNA synthetase beta subunit	glyS	-	6.1.1.14	ko:K01879	ko00970,map00970	M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_1,tRNA_synt_2f
k141_7307_1	35128.Thapsdraft1720	2.56e-06	48.5	COG0465@1|root,KOG0731@2759|Eukaryota,2XEEJ@2836|Bacillariophyta	2836|Bacillariophyta	O	Acts as a processive, ATP-dependent zinc metallopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	AAA,Peptidase_M41
k141_6085_1	926566.Terro_3850	4.58e-45	163.0	COG0055@1|root,COG0055@2|Bacteria,3Y2PU@57723|Acidobacteria,2JIDM@204432|Acidobacteriia	204432|Acidobacteriia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
k141_2391_1	1232410.KI421425_gene1549	3.35e-54	191.0	COG4105@1|root,COG4105@2|Bacteria,1QVQ9@1224|Proteobacteria,43CT2@68525|delta/epsilon subdivisions,2X80K@28221|Deltaproteobacteria,43TUA@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6
k141_5476_1	1283284.AZUK01000001_gene2308	2.13e-26	97.8	arCOG05874@1|root,2ZJ01@2|Bacteria,1N8VY@1224|Proteobacteria,1SHGZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_3009_1	1076550.LH22_17170	9.81e-27	104.0	2CC49@1|root,2ZBQQ@2|Bacteria,1RA92@1224|Proteobacteria,1S3BM@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF1367)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1367
k141_1155_1	1123037.AUDE01000015_gene2633	3.33e-25	99.8	COG3358@1|root,COG3358@2|Bacteria,4NNWJ@976|Bacteroidetes,1I20T@117743|Flavobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF1684)	-	-	-	ko:K09164	-	-	-	-	ko00000	-	-	-	DUF1684
k141_6086_1	391615.ABSJ01000045_gene2018	1.02e-40	143.0	COG1825@1|root,COG1825@2|Bacteria,1RDH0@1224|Proteobacteria,1S46A@1236|Gammaproteobacteria,1J5QI@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance	ctc	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02897	ko03010,map03010	M00178	-	-	ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L25p,Ribosomal_TL5_C
k141_9109_1	1304885.AUEY01000013_gene3130	1.97e-12	66.6	COG0766@1|root,COG0766@2|Bacteria,1MUH7@1224|Proteobacteria,42MJT@68525|delta/epsilon subdivisions,2WJ7W@28221|Deltaproteobacteria,2MHNI@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
k141_9109_2	396588.Tgr7_0743	1.16e-51	169.0	COG0040@1|root,COG0040@2|Bacteria,1MUCY@1224|Proteobacteria,1RNAX@1236|Gammaproteobacteria,1WX3P@135613|Chromatiales	135613|Chromatiales	E	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity	hisG	-	2.4.2.17	ko:K00765	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002,ko01000	-	-	-	HisG
k141_2392_1	1121904.ARBP01000041_gene4948	1.02e-27	109.0	COG1390@1|root,COG1390@2|Bacteria,4NTEY@976|Bacteroidetes	976|Bacteroidetes	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	-	-	-	ko:K02121	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_B,vATP-synt_E
k141_5477_1	1255043.TVNIR_3223	7.68e-96	289.0	COG0059@1|root,COG0059@2|Bacteria,1MV7M@1224|Proteobacteria,1RNA8@1236|Gammaproteobacteria,1WWXU@135613|Chromatiales	135613|Chromatiales	EH	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate	ilvC	-	1.1.1.86	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R03051,R04439,R04440,R05068,R05069,R05071	RC00726,RC00836,RC00837,RC01726	ko00000,ko00001,ko00002,ko01000	-	-	-	IlvC,IlvN
k141_1156_1	1223410.KN050846_gene1546	1.82e-76	251.0	COG2091@1|root,COG2091@2|Bacteria,4NFQ6@976|Bacteroidetes,1HWM8@117743|Flavobacteriia	976|Bacteroidetes	H	Carbohydrate family 9 binding domain-like	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
k141_3589_1	96561.Dole_0120	1.66e-56	188.0	COG0505@1|root,COG0505@2|Bacteria,1MUB9@1224|Proteobacteria,42KZG@68525|delta/epsilon subdivisions,2WIQ5@28221|Deltaproteobacteria,2MIKI@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Belongs to the CarA family	carA	-	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_sm_chain,GATase
k141_4246_1	641526.ADIWIN_1270	4.8e-30	112.0	COG1235@1|root,COG1235@2|Bacteria,4NDWB@976|Bacteroidetes,1HX58@117743|Flavobacteriia	976|Bacteroidetes	S	of the beta-lactamase superfamily I	phnP	-	3.1.4.55	ko:K06167	ko00440,map00440	-	R10205	RC00296	ko00000,ko00001,ko01000	-	-	-	Lactamase_B_2
k141_4246_2	886377.Murru_3035	4.11e-09	56.6	2CEU1@1|root,32S0H@2|Bacteria,4NM9W@976|Bacteroidetes,1I2DG@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_1774_1	1250232.JQNJ01000001_gene1753	2.16e-42	158.0	COG1361@1|root,COG2373@1|root,COG2911@1|root,COG3209@1|root,COG3291@1|root,COG5492@1|root,COG1361@2|Bacteria,COG2373@2|Bacteria,COG2911@2|Bacteria,COG3209@2|Bacteria,COG3291@2|Bacteria,COG5492@2|Bacteria	2|Bacteria	N	domain, Protein	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	CHU_C,DUF11
k141_542_1	45351.EDO30364	1.11e-07	60.5	KOG3594@1|root,KOG3594@2759|Eukaryota,38CZH@33154|Opisthokonta,3B9B2@33208|Metazoa	33208|Metazoa	Z	condensed mesenchymal cell proliferation	-	-	-	ko:K16669	ko04391,ko04392,map04391,map04392	-	-	-	ko00000,ko00001,ko04516	-	-	-	Cadherin
k141_6706_1	493475.GARC_2202	2.18e-55	194.0	COG2755@1|root,COG2755@2|Bacteria,1MXTS@1224|Proteobacteria,1RTPH@1236|Gammaproteobacteria,46419@72275|Alteromonadaceae	1236|Gammaproteobacteria	E	Concanavalin A-like lectin/glucanases superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3
k141_7311_1	246200.SPO2657	3.95e-20	89.0	COG2515@1|root,COG2515@2|Bacteria,1MVYF@1224|Proteobacteria,2TRCB@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Catalyzes a cyclopropane ring-opening reaction, the irreversible conversion of 1-aminocyclopropane-1-carboxylate (ACC) to ammonia and alpha-ketobutyrate. Allows growth on ACC as a nitrogen source	cuyA	GO:0000096,GO:0000098,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006520,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009987,GO:0016054,GO:0016829,GO:0016846,GO:0019752,GO:0019842,GO:0030170,GO:0034011,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044273,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901575	4.4.1.15,4.4.1.25	ko:K05396,ko:K17950	ko00270,map00270	-	R01874,R07634	RC00382,RC01784	ko00000,ko00001,ko01000	-	-	-	PALP
k141_7311_2	1121937.AUHJ01000009_gene1465	1.61e-27	112.0	COG0277@1|root,COG0277@2|Bacteria,1MU6Y@1224|Proteobacteria,1RQX2@1236|Gammaproteobacteria,465JD@72275|Alteromonadaceae	1236|Gammaproteobacteria	C	FAD linked oxidases, C-terminal domain	-	-	1.1.3.15	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
k141_3590_1	1380387.JADM01000008_gene857	2.9e-55	195.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,1XH3T@135619|Oceanospirillales	135619|Oceanospirillales	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k141_8521_1	395493.BegalDRAFT_0618	1.26e-77	240.0	COG0682@1|root,COG0682@2|Bacteria,1MVE3@1224|Proteobacteria,1RMVK@1236|Gammaproteobacteria,45ZW9@72273|Thiotrichales	72273|Thiotrichales	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
k141_4856_2	164328.Phyra72549	1.81e-30	133.0	COG2801@1|root,KOG0017@2759|Eukaryota,3QHRW@4776|Peronosporales	4776|Peronosporales	L	transposition, RNA-mediated	-	-	-	-	-	-	-	-	-	-	-	-	RVT_2
k141_2395_1	1278073.MYSTI_06468	2.57e-104	320.0	COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,42MHP@68525|delta/epsilon subdivisions,2WIQG@28221|Deltaproteobacteria,2YWF0@29|Myxococcales	28221|Deltaproteobacteria	I	Acetyl-coenzyme A synthetase N-terminus	acsA	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
k141_2396_1	2340.JV46_16860	1e-57	194.0	COG0452@1|root,COG0452@2|Bacteria,1MVQP@1224|Proteobacteria,1RMKQ@1236|Gammaproteobacteria,1J4KE@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	coaBC	GO:0000166,GO:0003674,GO:0003824,GO:0004632,GO:0004633,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0010181,GO:0015936,GO:0015937,GO:0016829,GO:0016830,GO:0016831,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032553,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	4.1.1.36,6.3.2.5	ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	iEC042_1314.EC042_3945,iECUMN_1333.ECUMN_4154,iJN746.PP_5285,iSBO_1134.SBO_3641	DFP,Flavoprotein
k141_9114_2	1249627.D779_3352	1.74e-34	131.0	COG0085@1|root,COG0085@2|Bacteria,1MUC4@1224|Proteobacteria,1RMK0@1236|Gammaproteobacteria,1WX4P@135613|Chromatiales	135613|Chromatiales	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	-	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
k141_3015_1	1122609.AUGT01000022_gene680	5.79e-14	75.9	COG0010@1|root,COG0010@2|Bacteria,2GJA6@201174|Actinobacteria,4DPV9@85009|Propionibacteriales	201174|Actinobacteria	E	Arginase family	-	-	3.5.3.11	ko:K01480	ko00330,ko01100,map00330,map01100	M00133	R01157	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
k141_4858_1	290397.Adeh_0837	8.9e-26	105.0	28PU4@1|root,2ZCF6@2|Bacteria,1RBK2@1224|Proteobacteria,43B3E@68525|delta/epsilon subdivisions,2X6H4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_546_1	1123037.AUDE01000033_gene3471	8.71e-78	238.0	COG0500@1|root,COG2226@2|Bacteria,4NE6P@976|Bacteroidetes,1HXEZ@117743|Flavobacteriia	976|Bacteroidetes	Q	Methyltransferase	rebM	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
k141_4249_1	159749.K0RL31	8.5e-31	128.0	COG2801@1|root,KOG0017@2759|Eukaryota,2XF4I@2836|Bacillariophyta	159749.K0RL31|-	L	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_7885_1	28258.KP05_08250	9.43e-110	328.0	COG0124@1|root,COG0124@2|Bacteria,1MV2K@1224|Proteobacteria,1RPHI@1236|Gammaproteobacteria,1XIK3@135619|Oceanospirillales	135619|Oceanospirillales	J	histidyl-tRNA synthetase	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
k141_8533_1	159749.K0S109	6.05e-14	70.1	2CZQV@1|root,2SBAE@2759|Eukaryota	2759|Eukaryota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_6718_1	187272.Mlg_1338	1.21e-105	321.0	COG0029@1|root,COG0029@2|Bacteria,1RBQW@1224|Proteobacteria,1RMMD@1236|Gammaproteobacteria,1WWEZ@135613|Chromatiales	135613|Chromatiales	H	Catalyzes the oxidation of L-aspartate to iminoaspartate	-	-	1.4.3.16	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	M00115	R00357,R00481	RC00006,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
k141_5488_1	7070.TC005160-PA	4.93e-12	76.6	COG2801@1|root,KOG0017@2759|Eukaryota,38F42@33154|Opisthokonta,3BA5H@33208|Metazoa,3CWAK@33213|Bilateria,41WI3@6656|Arthropoda,3SIRK@50557|Insecta	33208|Metazoa	O	K02A2.6-like	-	-	-	-	-	-	-	-	-	-	-	-	Asp_protease_2,RVT_1,Retrotrans_gag,gag-asp_proteas,rve,zf-CCHC,zf-H2C2
k141_552_1	1040989.AWZU01000009_gene1175	1.35e-10	65.1	COG0277@1|root,COG0277@2|Bacteria,1MU6Y@1224|Proteobacteria,2TR2Z@28211|Alphaproteobacteria,3JS63@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	FAD linked oxidases, C-terminal domain	dld	GO:0003674,GO:0003824,GO:0004457,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008720,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016491,GO:0016614,GO:0016616,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019866,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0034641,GO:0034654,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046034,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	1.1.1.303,1.1.1.4,1.1.2.4	ko:K00004,ko:K00102	ko00620,ko00650,map00620,map00650	-	R00197,R02855,R02946,R10504	RC00044,RC00205,RC00525	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
k141_552_2	935840.JAEQ01000019_gene2093	2.85e-27	108.0	COG1414@1|root,COG1414@2|Bacteria,1MUNW@1224|Proteobacteria,2TSY8@28211|Alphaproteobacteria,43J36@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	K	Transcriptional regulator	iclR	-	-	ko:K13641	-	-	-	-	ko00000,ko03000	-	-	-	HTH_IclR,IclR
k141_2407_1	1323663.AROI01000016_gene346	2.98e-73	234.0	COG1752@1|root,COG1752@2|Bacteria,1PDQ2@1224|Proteobacteria,1RMWI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	esterase of the alpha-beta hydrolase superfamily	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
k141_1167_1	1123518.ARWI01000001_gene1885	7.39e-41	151.0	COG0793@1|root,COG0793@2|Bacteria,1MU39@1224|Proteobacteria,1RMSR@1236|Gammaproteobacteria,45ZP3@72273|Thiotrichales	72273|Thiotrichales	M	Belongs to the peptidase S41A family	-	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_S41
k141_3025_1	1038860.AXAP01000048_gene6850	1.58e-54	188.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,2TR2W@28211|Alphaproteobacteria,3JU6X@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	IQ	AMP-binding enzyme C-terminal domain	MA20_18580	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
k141_7324_1	159749.K0TQC7	1.56e-31	129.0	COG2801@1|root,KOG0017@2759|Eukaryota,2XF4I@2836|Bacillariophyta	159749.K0TQC7|-	L	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_4870_1	159749.E7BWH6	1.5e-25	100.0	COG0450@1|root,KOG0852@2759|Eukaryota,2XFG5@2836|Bacillariophyta	2836|Bacillariophyta	O	Redoxin	ycf42	-	1.11.1.15	ko:K03386	ko04214,map04214	-	-	-	ko00000,ko00001,ko01000,ko04147	-	-	-	AhpC-TSA
k141_6102_1	930169.B5T_02380	8.75e-156	447.0	COG1219@1|root,COG1219@2|Bacteria,1MVQK@1224|Proteobacteria,1RN9N@1236|Gammaproteobacteria,1XH3A@135619|Oceanospirillales	135619|Oceanospirillales	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	-	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
k141_1788_1	1000565.METUNv1_02589	3.55e-44	148.0	COG0512@1|root,COG0512@2|Bacteria,1MV5Y@1224|Proteobacteria,2VHGQ@28216|Betaproteobacteria,2KVJD@206389|Rhodocyclales	206389|Rhodocyclales	EH	anthranilate	trpG	-	4.1.3.27	ko:K01658	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
k141_1788_2	666684.AfiDRAFT_1905	4.44e-11	63.9	COG0457@1|root,COG1413@1|root,COG0457@2|Bacteria,COG1413@2|Bacteria,1MX2U@1224|Proteobacteria,2TVI2@28211|Alphaproteobacteria,3JUS1@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	Cytochrome c554 and c-prime	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554,HEAT_2,Paired_CXXCH_1,TPR_14,TPR_16,TPR_19,TPR_2,TPR_8
k141_554_1	1342299.Z947_3576	1.54e-141	408.0	COG0477@1|root,COG2814@2|Bacteria,1MUXC@1224|Proteobacteria,2TRR7@28211|Alphaproteobacteria	28211|Alphaproteobacteria	EGP	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
k141_6103_1	1502724.FF80_03596	6.96e-40	136.0	COG0662@1|root,COG0662@2|Bacteria,1N51T@1224|Proteobacteria,2UCDE@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
k141_7326_1	391615.ABSJ01000054_gene1458	1.26e-64	216.0	COG1199@1|root,COG1199@2|Bacteria,1MVCU@1224|Proteobacteria,1RMNX@1236|Gammaproteobacteria,1J5D0@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	KL	HELICc2	yoaA	GO:0003674,GO:0003824,GO:0004386,GO:0006139,GO:0006259,GO:0006281,GO:0006301,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008026,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0070035,GO:0071704,GO:0090304,GO:1901360	3.6.4.12	ko:K03722	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DEAD_2,Helicase_C_2,ResIII
k141_9246_1	159749.E7BWK8	8.94e-111	347.0	COG0542@1|root,KOG1051@2759|Eukaryota,2XEW9@2836|Bacillariophyta	2836|Bacillariophyta	O	Belongs to the ClpA ClpB family	-	-	-	-	-	-	-	-	-	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
k141_9249_1	50452.A0A087G8H9	8.57e-05	48.9	COG2801@1|root,KOG0017@2759|Eukaryota,37THH@33090|Viridiplantae	33090|Viridiplantae	L	Mitochondrial protein	-	-	-	-	-	-	-	-	-	-	-	-	RVT_2
k141_8010_1	1090320.KB900605_gene2144	5.18e-91	275.0	COG3547@1|root,COG3547@2|Bacteria,1MUER@1224|Proteobacteria,2TQTP@28211|Alphaproteobacteria,2K2SD@204457|Sphingomonadales	204457|Sphingomonadales	L	Transposase	-	-	-	ko:K07486	-	-	-	-	ko00000	-	-	-	DEDD_Tnp_IS110,Transposase_20
k141_8013_1	395493.BegalDRAFT_0160	3.41e-56	187.0	COG1721@1|root,COG1721@2|Bacteria,1Q7RR@1224|Proteobacteria,1RNNP@1236|Gammaproteobacteria,460QI@72273|Thiotrichales	72273|Thiotrichales	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
k141_8013_2	765912.Thimo_2934	6.15e-23	95.9	COG0714@1|root,COG0714@2|Bacteria,1MUFN@1224|Proteobacteria,1RN5G@1236|Gammaproteobacteria,1X2CM@135613|Chromatiales	135613|Chromatiales	S	associated with various cellular activities	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
k141_8015_1	164328.Phyra74019	2.54e-22	104.0	29994@1|root,2RGAU@2759|Eukaryota,3QHY8@4776|Peronosporales	4776|Peronosporales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_7
k141_8016_1	83219.PM02_12705	5.1e-157	464.0	COG4664@1|root,COG4665@1|root,COG4664@2|Bacteria,COG4665@2|Bacteria,1R4MZ@1224|Proteobacteria,2TQNR@28211|Alphaproteobacteria,3ZW8Y@60136|Sulfitobacter	28211|Alphaproteobacteria	Q	Tripartite ATP-independent periplasmic transporter, DctM component	-	-	-	-	-	-	-	-	-	-	-	-	DctM,DctQ
k141_5553_1	391626.OAN307_c30510	1.19e-81	248.0	COG2801@1|root,COG2801@2|Bacteria,1MVC8@1224|Proteobacteria,2TRX0@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	COG2801 Transposase and inactivated derivatives	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve
k141_5553_2	766499.C357_01850	2.91e-59	187.0	COG2801@1|root,COG2963@1|root,COG2801@2|Bacteria,COG2963@2|Bacteria,1N8W3@1224|Proteobacteria,2UBXZ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	Transposase	-	-	-	ko:K07483	-	-	-	-	ko00000	-	-	-	HTH_Tnp_1
k141_2469_1	1229909.NSED_07735	4.66e-143	420.0	COG1389@1|root,arCOG01165@2157|Archaea,41SJ2@651137|Thaumarchaeota	651137|Thaumarchaeota	L	Relaxes both positive and negative superturns and exhibits a strong decatenase activity	top6B	-	5.99.1.3	ko:K03167	-	-	-	-	ko00000,ko01000,ko03032	-	-	-	HATPase_c,Topo-VIb_trans
k141_6787_1	391626.OAN307_c39080	5.85e-47	155.0	COG0735@1|root,COG0735@2|Bacteria,1MZIW@1224|Proteobacteria,2U9G4@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	Belongs to the Fur family	zur	-	-	ko:K09823	ko02024,map02024	-	-	-	ko00000,ko00001,ko03000	-	-	-	FUR
k141_6787_2	78245.Xaut_3903	2.83e-07	52.0	COG0410@1|root,COG0410@2|Bacteria,1MVVC@1224|Proteobacteria,2TR61@28211|Alphaproteobacteria,3EYUN@335928|Xanthobacteraceae	28211|Alphaproteobacteria	E	ATPases associated with a variety of cellular activities	livF	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
k141_4319_1	314225.ELI_08070	5.85e-08	52.8	COG0099@1|root,COG0099@2|Bacteria,1RD1G@1224|Proteobacteria,2U73D@28211|Alphaproteobacteria,2K4E3@204457|Sphingomonadales	204457|Sphingomonadales	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	rpsM	-	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
k141_4319_2	82508.K1UZX8	2.17e-71	228.0	COG1845@1|root,KOG4664@2759|Eukaryota,39ASV@33154|Opisthokonta,3NUQM@4751|Fungi,3V05G@5204|Basidiomycota	4751|Fungi	C	Subunits I, II and III form the functional core of the enzyme complex	cox3	GO:0003674,GO:0003824,GO:0004129,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005746,GO:0005751,GO:0006091,GO:0006119,GO:0006123,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009055,GO:0009060,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015002,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015672,GO:0015980,GO:0016020,GO:0016021,GO:0016310,GO:0016491,GO:0016675,GO:0016676,GO:0017144,GO:0019637,GO:0019646,GO:0019693,GO:0019866,GO:0022857,GO:0022890,GO:0022900,GO:0022904,GO:0031090,GO:0031224,GO:0031966,GO:0031967,GO:0031975,GO:0032991,GO:0034220,GO:0034641,GO:0042773,GO:0042775,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044281,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044444,GO:0044446,GO:0044455,GO:0044464,GO:0045277,GO:0045333,GO:0046034,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0055114,GO:0070069,GO:0070469,GO:0071704,GO:0072521,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098798,GO:0098800,GO:0098803,GO:1901135,GO:1901360,GO:1901564,GO:1902600	-	ko:K02262	ko00190,ko01100,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map04260,map04714,map04932,map05010,map05012,map05016	M00154	-	-	ko00000,ko00001,ko00002,ko03029	3.D.4.11,3.D.4.7,3.D.4.8	-	-	COX3
k141_617_1	1122137.AQXF01000001_gene3084	1.26e-30	129.0	COG2931@1|root,COG3210@1|root,COG2931@2|Bacteria,COG3210@2|Bacteria,1MU7T@1224|Proteobacteria,2TRVY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	COG2931 RTX toxins and related Ca2 -binding proteins	-	-	-	ko:K07004	-	-	-	-	ko00000	-	-	-	Calx-beta,DUF4347,HemolysinCabind,P_proprotein,Peptidase_M10,Peptidase_M10_C,Peptidase_S8
k141_1853_1	519989.ECTPHS_08788	8.85e-69	217.0	COG1475@1|root,COG1475@2|Bacteria,1MW2E@1224|Proteobacteria,1RN65@1236|Gammaproteobacteria,1WWNZ@135613|Chromatiales	135613|Chromatiales	K	Belongs to the ParB family	-	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
k141_5554_1	1218084.BBJK01000152_gene7607	1.09e-19	91.3	COG1028@1|root,COG1028@2|Bacteria,1PFUB@1224|Proteobacteria,2VP9J@28216|Betaproteobacteria,1K7UG@119060|Burkholderiaceae	28216|Betaproteobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
k141_6788_1	247490.KSU1_D0949	5.18e-78	245.0	COG0674@1|root,COG0674@2|Bacteria	2|Bacteria	C	oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor	porA	GO:0003674,GO:0003824,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016054,GO:0016491,GO:0016625,GO:0016903,GO:0019752,GO:0033609,GO:0033611,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0055114,GO:0071704,GO:1901575	1.2.7.1,1.2.7.10	ko:K00169,ko:K19070	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR_N
k141_9252_2	1305735.JAFT01000005_gene3633	9.84e-05	49.3	COG0845@1|root,COG0845@2|Bacteria,1MUFW@1224|Proteobacteria,2U2CU@28211|Alphaproteobacteria,2PFYN@252301|Oceanicola	28211|Alphaproteobacteria	M	Barrel-sandwich domain of CusB or HlyD membrane-fusion	-	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	HlyD_D23
k141_3705_1	234267.Acid_6181	9.61e-60	203.0	COG3379@1|root,COG3379@2|Bacteria,3Y7EC@57723|Acidobacteria	57723|Acidobacteria	S	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
k141_6172_1	1265313.HRUBRA_01563	5.3e-85	265.0	COG3547@1|root,COG3547@2|Bacteria,1QYJU@1224|Proteobacteria,1RN0A@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Transposase IS116 IS110 IS902	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k141_8020_1	398580.Dshi_0268	2.78e-96	311.0	COG0085@1|root,COG0085@2|Bacteria,1MUC4@1224|Proteobacteria,2TS7S@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
k141_6789_1	1430440.MGMSRv2_1764	1.51e-87	270.0	COG0536@1|root,COG0536@2|Bacteria,1MUGZ@1224|Proteobacteria,2TR5I@28211|Alphaproteobacteria,2JQWN@204441|Rhodospirillales	204441|Rhodospirillales	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	-	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	GTP1_OBG,MMR_HSR1
k141_4321_1	261292.Nit79A3_0042	2.27e-15	73.9	COG0356@1|root,COG0356@2|Bacteria,1MV87@1224|Proteobacteria,2VNK8@28216|Betaproteobacteria,3725X@32003|Nitrosomonadales	28216|Betaproteobacteria	C	it plays a direct role in the translocation of protons across the membrane	-	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
k141_4321_2	525897.Dbac_0947	3.25e-45	148.0	COG0636@1|root,COG0636@2|Bacteria,1NAIE@1224|Proteobacteria,42UFU@68525|delta/epsilon subdivisions,2WQ4V@28221|Deltaproteobacteria,2MCKY@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	-	-	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
k141_2473_1	1122176.KB903598_gene4581	5.86e-24	106.0	COG4935@1|root,COG4935@2|Bacteria,4NEN7@976|Bacteroidetes	976|Bacteroidetes	O	Pfam Proprotein convertase	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin_3,P_proprotein,Reprolysin_4
k141_1238_1	391593.RCCS2_12789	2.39e-135	391.0	COG0050@1|root,COG0050@2|Bacteria,1MVC0@1224|Proteobacteria,2TQP8@28211|Alphaproteobacteria,2P1WV@2433|Roseobacter	28211|Alphaproteobacteria	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
k141_4322_1	215803.DB30_5112	2.93e-19	87.8	COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,42M2E@68525|delta/epsilon subdivisions,2WKAB@28221|Deltaproteobacteria,2YWDZ@29|Myxococcales	28221|Deltaproteobacteria	K	Transcriptional regulator, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Sigma54_activat,V4R,XylR_N
k141_3706_1	713586.KB900536_gene2596	3.28e-139	407.0	COG0006@1|root,COG0006@2|Bacteria,1MUZS@1224|Proteobacteria,1RN0W@1236|Gammaproteobacteria,1WWJH@135613|Chromatiales	135613|Chromatiales	E	peptidase M24B, X-Pro dipeptidase aminopeptidase	-	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	AMP_N,Peptidase_M24
k141_8635_1	1298867.AUES01000126_gene5138	3.3e-60	196.0	COG0517@1|root,COG0517@2|Bacteria,1MXI6@1224|Proteobacteria,2TS6X@28211|Alphaproteobacteria,3JWIG@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Putative transposase	-	-	-	-	-	-	-	-	-	-	-	-	Y2_Tnp,Zn_Tnp_IS91
k141_8635_2	391616.OA238_c16390	1.17e-124	364.0	COG4974@1|root,COG4974@2|Bacteria,1MVAN@1224|Proteobacteria,2UDDB@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	Phage integrase, N-terminal SAM-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
k141_2475_1	388739.RSK20926_16662	1.23e-97	291.0	COG1018@1|root,COG1018@2|Bacteria,1MW37@1224|Proteobacteria,2TVXU@28211|Alphaproteobacteria,2P5AJ@2433|Roseobacter	28211|Alphaproteobacteria	C	COG1018 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1	fpr	-	1.18.1.2,1.19.1.1	ko:K00528	-	-	R10159	-	ko00000,ko01000	-	-	-	FAD_binding_6,NAD_binding_1
k141_1855_1	1120792.JAFV01000001_gene47	3.36e-06	48.1	COG3666@1|root,COG3666@2|Bacteria,1QW5T@1224|Proteobacteria,2TWNW@28211|Alphaproteobacteria,36Y0Y@31993|Methylocystaceae	28211|Alphaproteobacteria	L	Transposase DDE domain	tnp*	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_6,DUF772
k141_1855_2	366394.Smed_5052	6.02e-35	129.0	COG3335@1|root,COG3415@1|root,COG3335@2|Bacteria,COG3415@2|Bacteria,1P76X@1224|Proteobacteria,2U16U@28211|Alphaproteobacteria,4BC2J@82115|Rhizobiaceae	28211|Alphaproteobacteria	L	Transposase and inactivated	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,HTH_23
k141_1855_3	1040989.AWZU01000010_gene4290	9.44e-22	89.4	COG3335@1|root,COG3335@2|Bacteria,1P76X@1224|Proteobacteria,2U16U@28211|Alphaproteobacteria,3JUDA@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	L	DDE superfamily endonuclease	-	-	-	ko:K07494	-	-	-	-	ko00000	-	-	-	DDE_3,HTH_23
k141_9254_1	395019.Bmul_0305	3.1e-132	414.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1MU7B@1224|Proteobacteria,2VHUY@28216|Betaproteobacteria,1K0VQ@119060|Burkholderiaceae	28216|Betaproteobacteria	E	glutamate synthase	gltB	-	1.4.1.13,1.4.1.14,1.4.7.1	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	-	R00021,R00093,R00114,R00248,R10086	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
k141_8636_1	1131269.AQVV01000036_gene1492	9.6e-100	320.0	COG0085@1|root,COG0085@2|Bacteria	2|Bacteria	K	DNA-directed 5'-3' RNA polymerase activity	rpoB	GO:0000428,GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030880,GO:0032774,GO:0032991,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234	2.7.7.6	ko:K03043,ko:K13797	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
k141_7407_1	247633.GP2143_00942	5.03e-82	259.0	COG4147@1|root,COG4147@2|Bacteria,1MVJ8@1224|Proteobacteria,1RN0R@1236|Gammaproteobacteria,1J589@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	actP	-	-	ko:K14393	-	-	-	-	ko00000,ko02000	2.A.21.7	-	-	SSF
k141_7_1	247490.KSU1_C1449	5.24e-71	226.0	28HMZ@1|root,2Z7WD@2|Bacteria,2J2EK@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF3604)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3604
k141_9256_1	4577.GRMZM2G161242_P01	0.000905	48.5	KOG0118@1|root,KOG0118@2759|Eukaryota,37M86@33090|Viridiplantae,3GGB2@35493|Streptophyta,3KRIP@4447|Liliopsida,3I7ZC@38820|Poales	35493|Streptophyta	A	Zinc knuckle	-	GO:0001101,GO:0003674,GO:0003676,GO:0003677,GO:0003682,GO:0003723,GO:0003729,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005730,GO:0006355,GO:0006950,GO:0008150,GO:0009266,GO:0009409,GO:0009414,GO:0009415,GO:0009628,GO:0009889,GO:0009890,GO:0009892,GO:0009893,GO:0010035,GO:0010468,GO:0010556,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0016604,GO:0016607,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031490,GO:0031974,GO:0031981,GO:0033120,GO:0042221,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043484,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044451,GO:0044464,GO:0045892,GO:0045934,GO:0045935,GO:0048024,GO:0048026,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050684,GO:0050685,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0070013,GO:0080090,GO:0097159,GO:1901363,GO:1901700,GO:1902679,GO:1903311,GO:1903313,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141	-	ko:K12885	ko03040,map03040	-	-	-	ko00000,ko00001,ko03041	-	-	-	RRM_1,zf-CCHC
k141_3094_1	768671.ThimaDRAFT_2565	1.03e-28	117.0	COG4942@1|root,COG4942@2|Bacteria,1MY3E@1224|Proteobacteria,1RPQP@1236|Gammaproteobacteria,1WX4I@135613|Chromatiales	135613|Chromatiales	D	PFAM peptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
k141_5032_1	1380600.AUYN01000009_gene1765	2.12e-88	285.0	COG0341@1|root,COG0342@1|root,COG0341@2|Bacteria,COG0342@2|Bacteria,4NE1X@976|Bacteroidetes,1HY03@117743|Flavobacteriia	976|Bacteroidetes	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
k141_8093_1	1229909.NSED_08980	1.27e-11	63.5	COG0540@1|root,arCOG00911@2157|Archaea,41S6H@651137|Thaumarchaeota	651137|Thaumarchaeota	F	aspartate carbamoyltransferase	pyrB	-	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
k141_8093_2	436308.Nmar_1687	4.27e-75	226.0	COG1781@1|root,arCOG04229@2157|Archaea,41SJT@651137|Thaumarchaeota	651137|Thaumarchaeota	F	Involved in allosteric regulation of aspartate carbamoyltransferase	pyrI	-	-	ko:K00610	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002	-	-	-	PyrI,PyrI_C
k141_4420_1	460265.Mnod_4838	1.45e-58	197.0	COG0028@1|root,COG0028@2|Bacteria,1MXDW@1224|Proteobacteria,2TT9X@28211|Alphaproteobacteria,1JSHK@119045|Methylobacteriaceae	28211|Alphaproteobacteria	EH	Belongs to the TPP enzyme family	oxc	-	4.1.1.8	ko:K01577	ko00630,ko01100,map00630,map01100	-	R01908	RC00620	ko00000,ko00001,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
k141_5645_1	765914.ThisiDRAFT_0270	1.02e-61	204.0	COG0593@1|root,COG0593@2|Bacteria,1MU5H@1224|Proteobacteria,1RNHP@1236|Gammaproteobacteria,1WW6C@135613|Chromatiales	135613|Chromatiales	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	-	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
k141_6878_1	1297742.A176_06744	2.85e-12	71.2	COG0617@1|root,COG0617@2|Bacteria,1MVCS@1224|Proteobacteria,42QKZ@68525|delta/epsilon subdivisions,2WJ74@28221|Deltaproteobacteria,2YU8X@29|Myxococcales	28221|Deltaproteobacteria	H	Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control	pcnB	-	2.7.7.19,2.7.7.72	ko:K00970,ko:K00974	ko03013,ko03018,map03013,map03018	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	PolyA_pol,PolyA_pol_RNAbd,PolyA_pol_arg_C
k141_8708_1	1469245.JFBG01000097_gene1350	2.95e-98	296.0	COG0683@1|root,COG0683@2|Bacteria,1MWQB@1224|Proteobacteria	1224|Proteobacteria	E	COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
k141_3176_1	1411123.JQNH01000001_gene302	8.21e-59	199.0	COG0747@1|root,COG0747@2|Bacteria,1MUZH@1224|Proteobacteria,2TQQH@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	ABC-type dipeptide transport system periplasmic component	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
k141_5646_1	323097.Nham_2531	6.65e-50	179.0	COG3459@1|root,COG3459@2|Bacteria,1MVNX@1224|Proteobacteria,2TSAJ@28211|Alphaproteobacteria,3JWMN@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	M	Glycosyl hydrolase 36 superfamily, catalytic domain	ndvB	GO:0003674,GO:0003824,GO:0016740,GO:0016757	2.4.1.321	ko:K13688,ko:K18786	-	-	R10832	RC00397	ko00000,ko01000,ko01003	-	GH94,GT84	-	Glyco_hydro_36,Glyco_transf_36,Glycoamylase
k141_6879_1	667632.KB890169_gene5008	2.84e-64	198.0	COG0822@1|root,COG0822@2|Bacteria,1RD5K@1224|Proteobacteria,2VQ2I@28216|Betaproteobacteria,1K6Y7@119060|Burkholderiaceae	28216|Betaproteobacteria	C	A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters	iscU	-	-	ko:K04488	-	-	-	-	ko00000	-	-	-	NifU_N
k141_6879_2	948565.AFFP02000004_gene728	7.52e-28	109.0	COG1104@1|root,COG1104@2|Bacteria,1MU1C@1224|Proteobacteria,1RNCD@1236|Gammaproteobacteria,1Y7JT@135625|Pasteurellales	135625|Pasteurellales	H	Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
k141_5034_1	1123401.JHYQ01000005_gene247	3.79e-82	257.0	COG0247@1|root,COG0247@2|Bacteria,1MUMH@1224|Proteobacteria,1RNBY@1236|Gammaproteobacteria,4637B@72273|Thiotrichales	72273|Thiotrichales	C	Fe-S oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_8
k141_7471_1	436308.Nmar_0091	1.21e-16	76.6	COG0842@1|root,arCOG01467@2157|Archaea,41SH0@651137|Thaumarchaeota	651137|Thaumarchaeota	V	ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
k141_7471_2	1229909.NSED_00150	8.33e-78	239.0	COG1131@1|root,arCOG00196@2157|Archaea,41S9H@651137|Thaumarchaeota	651137|Thaumarchaeota	V	ABC-type multidrug transport system, ATPase component	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
k141_8095_1	243159.AFE_0893	7.88e-20	88.2	COG0182@1|root,COG0182@2|Bacteria,1MUPM@1224|Proteobacteria,1RMGC@1236|Gammaproteobacteria,2NC3M@225057|Acidithiobacillales	225057|Acidithiobacillales	J	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)	mtnA	-	5.3.1.23	ko:K08963	ko00270,ko01100,map00270,map01100	M00034	R04420	RC01151	ko00000,ko00001,ko00002,ko01000	-	-	-	IF-2B
k141_6270_1	870187.Thini_0877	1.65e-46	164.0	COG0843@1|root,COG0843@2|Bacteria,1QJ23@1224|Proteobacteria,1SKBI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Cytochrome C and Quinol oxidase polypeptide I	-	-	-	-	-	-	-	-	-	-	-	-	COX1
k141_4423_1	911045.PSE_5008	1.62e-25	108.0	COG2871@1|root,COG2871@2|Bacteria,1QTUV@1224|Proteobacteria,2TWD7@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway	nqrF	-	1.6.5.8	ko:K00351,ko:K16246	ko00361,ko00362,ko00623,ko01100,ko01120,ko01220,map00361,map00362,map00623,map01100,map01120,map01220	M00548	R03560,R03608,R10042,R10043	RC00046,RC00490	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_6,Fer2,NAD_binding_1,PepSY_TM
k141_3178_1	526222.Desal_1903	1.58e-26	114.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42MXI@68525|delta/epsilon subdivisions,2WIX9@28221|Deltaproteobacteria,2M8PP@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	histidine kinase HAMP region domain protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal,PAS,PAS_4,PAS_9,dCache_1
k141_5648_1	472759.Nhal_2016	5.11e-53	182.0	COG5008@1|root,COG5008@2|Bacteria,1QTTX@1224|Proteobacteria,1RN0B@1236|Gammaproteobacteria,1WX16@135613|Chromatiales	135613|Chromatiales	NU	PFAM Type II secretion system protein E	-	-	-	ko:K02670	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
k141_8096_1	1342302.JASC01000014_gene1973	2.22e-53	183.0	COG1007@1|root,COG1007@2|Bacteria,1MV56@1224|Proteobacteria,2TQMX@28211|Alphaproteobacteria,3ZWJ7@60136|Sulfitobacter	28211|Alphaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
k141_6271_1	290400.Jann_2848	1.57e-79	250.0	COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,2TQND@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	bioA	-	2.6.1.18	ko:K00822	ko00280,ko00410,ko00640,ko01100,map00280,map00410,map00640,map01100	-	R00907,R04187	RC00008,RC00062,RC00160	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_3
k141_8711_1	1266914.ATUK01000010_gene1220	6.94e-87	266.0	COG0492@1|root,COG0492@2|Bacteria,1MV15@1224|Proteobacteria,1RMEX@1236|Gammaproteobacteria,1WWPK@135613|Chromatiales	135613|Chromatiales	C	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
k141_4424_1	4565.Traes_3AS_6706B4CCE.1	4.35e-11	62.4	COG1290@1|root,KOG4663@2759|Eukaryota,37PDF@33090|Viridiplantae,3GF4E@35493|Streptophyta,3KT2J@4447|Liliopsida,3IGFM@38820|Poales	35493|Streptophyta	C	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis	cob	-	-	ko:K00412	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002,ko03029	-	-	-	Cytochrom_B_C,Cytochrome_B
k141_4424_2	243365.CV_0600	7.11e-09	57.8	COG0843@1|root,COG0843@2|Bacteria,1MU7S@1224|Proteobacteria,2VHGU@28216|Betaproteobacteria,2KQHZ@206351|Neisseriales	206351|Neisseriales	C	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B	coxA	-	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
k141_6882_1	1262449.CP6013_3696	7.76e-23	97.4	COG3344@1|root,COG3344@2|Bacteria,1TP9A@1239|Firmicutes,24VWQ@186801|Clostridia,36TFH@31979|Clostridiaceae	186801|Clostridia	L	Reverse transcriptase	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_99_1	4565.EPlTAEP00000010100	1.28e-109	337.0	COG1007@1|root,KOG4668@2759|Eukaryota,37NNE@33090|Viridiplantae,3GBUN@35493|Streptophyta,3KM7Q@4447|Liliopsida,3IE0D@38820|Poales	35493|Streptophyta	C	Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone	-	-	1.6.5.3	ko:K03883	ko00190,ko01100,ko04714,ko04723,ko05012,map00190,map01100,map04714,map04723,map05012	M00142	R11945	RC00061	ko00000,ko00001,ko00002,ko01000,ko03029	3.D.1.6	-	-	NADH5_C,Proton_antipo_M,Proton_antipo_N
k141_2570_1	583355.Caka_1758	6.4e-96	293.0	COG1233@1|root,COG1233@2|Bacteria,46YTW@74201|Verrucomicrobia,3K7V6@414999|Opitutae	414999|Opitutae	Q	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
k141_5037_1	1211114.ALIP01000098_gene1816	2.88e-93	297.0	COG0542@1|root,COG0542@2|Bacteria,1MURH@1224|Proteobacteria,1RN55@1236|Gammaproteobacteria,1X499@135614|Xanthomonadales	135614|Xanthomonadales	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
k141_1957_1	1105367.CG50_03105	6.79e-09	58.5	COG0277@1|root,COG0277@2|Bacteria,1MU6Y@1224|Proteobacteria,2TRYI@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	COG0277 FAD FMN-containing dehydrogenases	-	-	-	-	-	-	-	-	-	-	-	-	FAD-oxidase_C,FAD_binding_4
k141_1957_2	1458357.BG58_13120	1.01e-29	117.0	COG0028@1|root,COG0028@2|Bacteria,1MWVW@1224|Proteobacteria,2VQU4@28216|Betaproteobacteria,1K2YI@119060|Burkholderiaceae	28216|Betaproteobacteria	EH	Belongs to the TPP enzyme family	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
k141_4425_1	504487.JCM19302_1314	4.97e-90	276.0	COG1983@1|root,COG1983@2|Bacteria,4NG3T@976|Bacteroidetes,1HX01@117743|Flavobacteriia	976|Bacteroidetes	KT	PspC domain	-	-	-	ko:K03973	-	-	-	-	ko00000,ko02048,ko03000	-	-	-	DUF2807,PspC
k141_100_1	314345.SPV1_04343	4.05e-32	114.0	COG0776@1|root,COG0776@2|Bacteria,1MZ5B@1224|Proteobacteria	1224|Proteobacteria	L	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions	hupB	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
k141_5038_1	1454004.AW11_02554	6.63e-53	174.0	COG0400@1|root,COG0400@2|Bacteria,1RA02@1224|Proteobacteria,2VJ6G@28216|Betaproteobacteria,1KQ05@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	S	General function prediction only	estB	-	-	ko:K06999	-	-	-	-	ko00000	-	-	-	Abhydrolase_2
k141_7474_1	1342299.Z947_1128	1.99e-55	185.0	COG3515@1|root,COG3515@2|Bacteria,1NK35@1224|Proteobacteria,2VBD2@28211|Alphaproteobacteria,3ZVXN@60136|Sulfitobacter	28211|Alphaproteobacteria	S	ImpA, N-terminal, type VI secretion system	-	-	-	-	-	-	-	-	-	-	-	-	ImpA_N
k141_722_1	1122236.KB905143_gene276	4.19e-11	68.2	COG0019@1|root,COG0019@2|Bacteria,1MUA6@1224|Proteobacteria,2VI3M@28216|Betaproteobacteria,2KKUY@206350|Nitrosomonadales	206350|Nitrosomonadales	E	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine	lysA	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
k141_5722_1	313598.MED152_10030	3.49e-75	227.0	COG0782@1|root,COG0782@2|Bacteria,4NNH6@976|Bacteroidetes,1I18I@117743|Flavobacteriia,3VW7V@52959|Polaribacter	976|Bacteroidetes	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	-	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
k141_8162_1	89187.ISM_07825	5.3e-113	345.0	COG0446@1|root,COG1902@1|root,COG0446@2|Bacteria,COG1902@2|Bacteria,1MVE0@1224|Proteobacteria,2TQV0@28211|Alphaproteobacteria,46NKF@74030|Roseovarius	28211|Alphaproteobacteria	C	COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_FMN,Pyr_redox_2
k141_4499_1	1442598.JABW01000006_gene692	2.9e-12	71.2	COG3385@1|root,COG3385@2|Bacteria,1RM2A@1224|Proteobacteria,42WE3@68525|delta/epsilon subdivisions,2YSH2@29547|Epsilonproteobacteria	68525|delta/epsilon subdivisions	L	Transposase DDE domain group 1	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_4
k141_3873_1	1278073.MYSTI_05851	1.8e-49	177.0	COG0737@1|root,COG0737@2|Bacteria,1MX03@1224|Proteobacteria,42Q71@68525|delta/epsilon subdivisions,2WK8Q@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	Belongs to the 5'-nucleotidase family	-	-	3.1.3.5	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	5_nucleotid_C,Metallophos
k141_2650_1	977880.RALTA_A1227	1.64e-64	216.0	COG0204@1|root,COG0204@2|Bacteria,1MWDY@1224|Proteobacteria,2VJ4I@28216|Betaproteobacteria,1K1BW@119060|Burkholderiaceae	28216|Betaproteobacteria	I	Glycerol acyltransferase	aas	-	2.3.1.40,6.2.1.20	ko:K05939	ko00071,ko00564,map00071,map00564	-	R01406,R04864	RC00014,RC00039,RC00041	ko00000,ko00001,ko01000	-	-	-	Acyltransferase,MFS_1
k141_5723_1	1380387.JADM01000004_gene2801	1.28e-74	244.0	COG0210@1|root,COG0210@2|Bacteria,1MU0G@1224|Proteobacteria,1RNJI@1236|Gammaproteobacteria,1XIU4@135619|Oceanospirillales	135619|Oceanospirillales	L	Unwinds DNA duplexes with 3' to 5' polarity with respect to the bound strand and initiates unwinding most effectively when a single-stranded region is present	uvrD	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
k141_6965_1	247639.MGP2080_09076	2.45e-59	196.0	COG1960@1|root,COG1960@2|Bacteria,1MU2V@1224|Proteobacteria,1S3EX@1236|Gammaproteobacteria,1J7QG@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
k141_176_1	765912.Thimo_0083	8.43e-43	154.0	COG4972@1|root,COG4972@2|Bacteria,1MX8P@1224|Proteobacteria,1RN8S@1236|Gammaproteobacteria,1WXGR@135613|Chromatiales	135613|Chromatiales	NU	TIGRFAM type IV pilus assembly protein PilM	-	-	-	ko:K02662	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilM_2
k141_7534_1	1116472.MGMO_116c00330	7.3e-67	225.0	COG0058@1|root,COG0058@2|Bacteria,1MW4J@1224|Proteobacteria,1RN8P@1236|Gammaproteobacteria,1XDP7@135618|Methylococcales	135618|Methylococcales	F	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties	-	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	Phosphorylase
k141_1413_1	102129.Lepto7375DRAFT_6427	9.07e-05	49.3	COG1595@1|root,COG1595@2|Bacteria,1G34M@1117|Cyanobacteria,1HA6K@1150|Oscillatoriales	1117|Cyanobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
k141_6351_1	314278.NB231_07327	3.85e-83	273.0	COG1197@1|root,COG1197@2|Bacteria,1MUXG@1224|Proteobacteria,1RNCU@1236|Gammaproteobacteria,1WWJQ@135613|Chromatiales	135613|Chromatiales	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
k141_4502_1	35128.Thapsdraft1327	6.34e-15	75.1	COG0305@1|root,2QRXQ@2759|Eukaryota,2XEMK@2836|Bacillariophyta	2836|Bacillariophyta	L	DnaB-like helicase N terminal domain	dnaB	-	-	-	-	-	-	-	-	-	-	-	DnaB,DnaB_C
k141_8778_1	1249627.D779_1971	1.9e-70	229.0	COG3344@1|root,COG3344@2|Bacteria,1MVI1@1224|Proteobacteria,1RQP7@1236|Gammaproteobacteria,1X044@135613|Chromatiales	135613|Chromatiales	L	PFAM Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	GIIM,RVT_1
k141_2653_1	1208323.B30_12157	1.89e-120	351.0	COG0825@1|root,COG0825@2|Bacteria,1MURN@1224|Proteobacteria,2TR6V@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA	accA	-	2.1.3.15,6.4.1.2	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	ACCA
k141_1414_1	391589.RGAI101_1915	5.67e-05	50.4	COG0697@1|root,COG0697@2|Bacteria,1RFZW@1224|Proteobacteria,2TRXD@28211|Alphaproteobacteria,2P2NG@2433|Roseobacter	28211|Alphaproteobacteria	EG	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily	-	-	-	-	-	-	-	-	-	-	-	-	EamA
k141_4503_1	1304275.C41B8_18186	9.8e-40	151.0	COG0243@1|root,COG0243@2|Bacteria,1P01N@1224|Proteobacteria,1SYHR@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Molybdop_Fe4S4,Molybdopterin
k141_5119_2	317619.ANKN01000163_gene505	8.86e-33	121.0	COG1451@1|root,COG1451@2|Bacteria,1G6GG@1117|Cyanobacteria	1117|Cyanobacteria	S	Metal-dependent hydrolase	-	-	-	ko:K07043	-	-	-	-	ko00000	-	-	-	DUF45
k141_3257_1	640081.Dsui_1456	3.08e-94	292.0	COG2203@1|root,COG2206@1|root,COG2203@2|Bacteria,COG2206@2|Bacteria,1MV37@1224|Proteobacteria,2VJ21@28216|Betaproteobacteria,2KVJ8@206389|Rhodocyclales	206389|Rhodocyclales	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	3.1.4.17	ko:K01120	ko00230,map00230	-	R00191,R01234	RC00296	ko00000,ko00001,ko01000	-	-	-	FHA,GAF,HD,HD_5
k141_8779_1	314285.KT71_12795	3.2e-37	140.0	COG0624@1|root,COG0624@2|Bacteria,1R96A@1224|Proteobacteria,1RSD6@1236|Gammaproteobacteria,1J8ZH@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	E	Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
k141_2654_1	1547437.LL06_17135	1.65e-27	114.0	COG1233@1|root,COG1233@2|Bacteria,1MV2R@1224|Proteobacteria,2TSR0@28211|Alphaproteobacteria,43GY1@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	Q	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase,NAD_binding_8
k141_8167_1	751994.AGIG01000028_gene1918	1.52e-67	214.0	COG0224@1|root,COG0224@2|Bacteria,1MU28@1224|Proteobacteria,1RNWJ@1236|Gammaproteobacteria,1J4Q3@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0036442,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	iSSON_1240.SSON_3886,iYL1228.KPN_04138	ATP-synt
k141_1415_1	697282.Mettu_0785	8.19e-82	258.0	COG0129@1|root,COG0129@2|Bacteria,1MUTQ@1224|Proteobacteria,1RMP2@1236|Gammaproteobacteria,1XESA@135618|Methylococcales	135618|Methylococcales	H	Belongs to the IlvD Edd family	ilvD	-	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
k141_179_1	768706.Desor_2211	3.26e-23	100.0	COG4974@1|root,COG4974@2|Bacteria,1TR57@1239|Firmicutes,24ACW@186801|Clostridia,26128@186807|Peptococcaceae	186801|Clostridia	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
k141_4504_1	452637.Oter_3626	2.93e-49	168.0	COG0517@1|root,COG1994@1|root,COG0517@2|Bacteria,COG1994@2|Bacteria,46SM2@74201|Verrucomicrobia,3K9SZ@414999|Opitutae	414999|Opitutae	S	Peptidase M50	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_801_1	159749.E7BWE0	2.43e-91	273.0	COG0805@1|root,2QVCB@2759|Eukaryota	2759|Eukaryota	U	protein transport by the Tat complex	tatC	GO:0000003,GO:0003674,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006810,GO:0006886,GO:0006996,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009507,GO:0009534,GO:0009535,GO:0009536,GO:0009566,GO:0009567,GO:0009579,GO:0009657,GO:0009668,GO:0009977,GO:0009987,GO:0010027,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0019953,GO:0022414,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0031360,GO:0031361,GO:0031976,GO:0031984,GO:0032991,GO:0033036,GO:0033281,GO:0034357,GO:0034613,GO:0042651,GO:0042886,GO:0042887,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043235,GO:0043953,GO:0044422,GO:0044424,GO:0044425,GO:0044434,GO:0044435,GO:0044436,GO:0044444,GO:0044446,GO:0044459,GO:0044464,GO:0044703,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0051704,GO:0055035,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0098796,GO:0098797,GO:1904680	-	ko:K02634,ko:K03118	ko00195,ko01100,ko03060,ko03070,map00195,map01100,map03060,map03070	M00162,M00336	-	-	ko00000,ko00001,ko00002,ko00194,ko02044	2.A.64	-	-	TatC
k141_8781_1	1396141.BATP01000045_gene1824	1.08e-114	342.0	COG5557@1|root,COG5557@2|Bacteria,46S9S@74201|Verrucomicrobia,2ITK9@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	Polysulphide reductase, NrfD	-	-	-	ko:K00185	-	-	-	-	ko00000	5.A.3	-	-	NrfD
k141_5122_1	1484460.JSWG01000008_gene2061	4.55e-18	84.3	COG0811@1|root,COG0811@2|Bacteria,4NFIX@976|Bacteroidetes,1HXWI@117743|Flavobacteriia	976|Bacteroidetes	U	Mota tolq exbb proton channel	exbB	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
k141_803_1	932213.SPM24T3_23472	3.97e-56	183.0	COG1028@1|root,COG1028@2|Bacteria,1MU6X@1224|Proteobacteria,1RMBB@1236|Gammaproteobacteria,4017V@613|Serratia	1236|Gammaproteobacteria	IQ	Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis	-	-	1.1.1.100,1.1.1.36	ko:K00023,ko:K00059	ko00061,ko00333,ko00630,ko00650,ko00780,ko01040,ko01100,ko01120,ko01130,ko01200,ko01212,map00061,map00333,map00630,map00650,map00780,map01040,map01100,map01120,map01130,map01200,map01212	M00083,M00373,M00572	R01779,R01977,R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00103,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
k141_5241_1	1395571.TMS3_0124540	2.12e-74	238.0	COG3666@1|root,COG3666@2|Bacteria,1N3QR@1224|Proteobacteria,1S01K@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	COG3666 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_6,DUF772
k141_7086_1	278957.ABEA03000218_gene252	2.07e-31	125.0	COG4992@1|root,COG4992@2|Bacteria,46UBT@74201|Verrucomicrobia,3K8TC@414999|Opitutae	414999|Opitutae	E	Aminotransferase class-III	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_3
k141_4629_1	870187.Thini_3053	3.74e-59	192.0	COG0462@1|root,COG0462@2|Bacteria,1MUV7@1224|Proteobacteria,1RY55@1236|Gammaproteobacteria,461QU@72273|Thiotrichales	72273|Thiotrichales	F	N-terminal domain of ribose phosphate pyrophosphokinase	-	-	-	-	-	-	-	-	-	-	-	-	Pribosyltran,Pribosyltran_N
k141_4629_2	1122137.AQXF01000004_gene1656	4.43e-10	60.5	COG0213@1|root,COG0213@2|Bacteria,1MV3H@1224|Proteobacteria,2TS24@28211|Alphaproteobacteria	28211|Alphaproteobacteria	F	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis	-	GO:0003674,GO:0003824,GO:0004645,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016757,GO:0016758,GO:0044424,GO:0044444,GO:0044464	2.4.2.4	ko:K00758	ko00240,ko00983,ko01100,ko05219,map00240,map00983,map01100,map05219	-	R01570,R02484,R08222,R08230	RC00063	ko00000,ko00001,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3,PYNP_C
k141_5854_1	765913.ThidrDRAFT_0081	1.11e-48	175.0	COG4232@1|root,COG4232@2|Bacteria,1MU8W@1224|Proteobacteria,1RPF7@1236|Gammaproteobacteria,1WWWW@135613|Chromatiales	135613|Chromatiales	CO	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps	dsbD	-	1.8.1.8	ko:K04084	-	-	-	-	ko00000,ko01000,ko03110	5.A.1.1	-	-	DsbC,DsbD,Thioredoxin_7
k141_3372_1	1229909.NSED_08500	2.35e-09	57.0	arCOG08777@1|root,arCOG08647@2157|Archaea,41SNX@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_3372_2	1229909.NSED_08495	1.25e-44	152.0	arCOG08035@1|root,arCOG08035@2157|Archaea,41SQD@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_307_1	761193.Runsl_0284	4.59e-36	140.0	COG2366@1|root,COG2366@2|Bacteria,4NGXQ@976|Bacteroidetes,47JE7@768503|Cytophagia	976|Bacteroidetes	S	Penicillin amidase	-	-	3.5.1.97	ko:K07116	-	-	-	-	ko00000,ko01000	-	-	-	Penicil_amidase
k141_7652_2	999611.KI421504_gene2534	1.89e-62	192.0	COG2963@1|root,COG2963@2|Bacteria,1N1AA@1224|Proteobacteria,2UC5K@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Tnp_1
k141_7652_3	999611.KI421504_gene2535	6.21e-191	533.0	COG2801@1|root,COG2801@2|Bacteria,1MVXQ@1224|Proteobacteria,2TU72@28211|Alphaproteobacteria,2829J@191028|Leisingera	28211|Alphaproteobacteria	L	HTH-like domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_21,rve,rve_3
k141_1542_1	1121374.KB891576_gene438	1.45e-80	251.0	COG0686@1|root,COG0686@2|Bacteria,1QTX1@1224|Proteobacteria,1T1JB@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Belongs to the AlaDH PNT family	ald	-	1.4.1.1	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	-	R00396	RC00008	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
k141_8288_1	2340.JV46_27420	3.21e-33	124.0	COG2143@1|root,COG2143@2|Bacteria,1R72D@1224|Proteobacteria,1RSDK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	Thioredoxin-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_2
k141_8288_2	543913.D521_0307	1.23e-59	199.0	COG0662@1|root,COG0836@1|root,COG0662@2|Bacteria,COG0836@2|Bacteria,1MV39@1224|Proteobacteria,2VI4S@28216|Betaproteobacteria,1KQF2@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	M	Mannose-6-phosphate isomerase	cpsB	-	2.7.7.13,5.3.1.8	ko:K00971,ko:K16011	ko00051,ko00520,ko01100,ko01110,ko01130,ko02025,map00051,map00520,map01100,map01110,map01130,map02025	M00114,M00361,M00362	R00885,R01819	RC00002,RC00376	ko00000,ko00001,ko00002,ko01000	-	-	-	MannoseP_isomer,NTP_transferase
k141_4006_1	1121875.KB907548_gene1635	1.37e-130	390.0	COG1680@1|root,COG1680@2|Bacteria,4NI1Z@976|Bacteroidetes,1HYQF@117743|Flavobacteriia	976|Bacteroidetes	V	COG1680 Beta-lactamase class C and other penicillin binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
k141_3375_1	290400.Jann_3703	2.06e-105	322.0	COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,2TRKS@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	acsA	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
k141_8897_1	1121875.KB907546_gene2680	1.54e-120	359.0	COG0308@1|root,COG0308@2|Bacteria,4NGUB@976|Bacteroidetes,1HXVD@117743|Flavobacteriia	976|Bacteroidetes	E	peptidase M1	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
k141_5245_1	1336803.PHEL49_1245	1.17e-68	221.0	COG1668@1|root,COG1668@2|Bacteria,4NFSZ@976|Bacteroidetes,1HXQA@117743|Flavobacteriia,3VV0K@52959|Polaribacter	976|Bacteroidetes	CP	ABC-2 family transporter protein	natB	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
k141_4007_1	1041146.ATZB01000008_gene2192	5.47e-46	167.0	28HMZ@1|root,2Z7WD@2|Bacteria,1MU3Q@1224|Proteobacteria,2TSGX@28211|Alphaproteobacteria,4BCDP@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Protein of unknown function (DUF3604)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3604
k141_5857_1	2850.Phatr34423	7.92e-85	285.0	COG2801@1|root,KOG0017@2759|Eukaryota,2XEGG@2836|Bacillariophyta	2836|Bacillariophyta	L	transposition, RNA-mediated	-	-	-	-	-	-	-	-	-	-	-	-	RVT_2,gag_pre-integrs,rve,zf-CCHC
k141_7091_1	523791.Kkor_2455	4.78e-55	194.0	COG0403@1|root,COG1003@1|root,COG0403@2|Bacteria,COG1003@2|Bacteria,1MUDP@1224|Proteobacteria,1RND3@1236|Gammaproteobacteria,1XH72@135619|Oceanospirillales	135619|Oceanospirillales	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvP	-	1.4.4.2	ko:K00281,ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko00002,ko01000	-	-	-	GDC-P
k141_312_1	391595.RLO149_c025620	2.51e-64	206.0	COG4105@1|root,COG4105@2|Bacteria,1MVS5@1224|Proteobacteria,2TRZ5@28211|Alphaproteobacteria,2P2AR@2433|Roseobacter	28211|Alphaproteobacteria	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamD	-	-	ko:K05807	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	YfiO
k141_8898_1	1205680.CAKO01000010_gene3923	0.000194	41.6	COG0721@1|root,COG0721@2|Bacteria,1MZQP@1224|Proteobacteria,2UBSZ@28211|Alphaproteobacteria,2JU0Q@204441|Rhodospirillales	204441|Rhodospirillales	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatC	-	6.3.5.6,6.3.5.7	ko:K02435	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Glu-tRNAGln
k141_4634_1	396588.Tgr7_2279	1.58e-81	264.0	COG0495@1|root,COG0495@2|Bacteria,1MV47@1224|Proteobacteria,1RP14@1236|Gammaproteobacteria,1WW5E@135613|Chromatiales	135613|Chromatiales	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	-	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
k141_6484_1	1185652.USDA257_c45500	3.49e-92	283.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,2TQKE@28211|Alphaproteobacteria,4B7TB@82115|Rhizobiaceae	28211|Alphaproteobacteria	I	acyl-CoA dehydrogenase	acdA	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
k141_2776_1	1530186.JQEY01000010_gene2812	6.27e-27	108.0	COG0706@1|root,COG0706@2|Bacteria,1MV5M@1224|Proteobacteria,2TSTJ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	U	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins	yidC	GO:0002790,GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0032940,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP,YidC_periplas
k141_2776_2	1188256.BASI01000001_gene359	3.94e-40	141.0	COG3217@1|root,COG3217@2|Bacteria,1MVSP@1224|Proteobacteria,2U1ST@28211|Alphaproteobacteria,3FDUD@34008|Rhodovulum	28211|Alphaproteobacteria	S	MOSC domain	-	-	-	ko:K07140	-	-	-	-	ko00000	-	-	-	MOSC,MOSC_N
k141_1546_1	335659.S23_62080	1.25e-83	275.0	COG1014@1|root,COG4231@1|root,COG1014@2|Bacteria,COG4231@2|Bacteria,1MUKS@1224|Proteobacteria,2TSHH@28211|Alphaproteobacteria,3JVSS@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	Pyruvate ferredoxin/flavodoxin oxidoreductase	MA20_06130	-	1.2.7.8	ko:K04090	-	-	-	-	br01601,ko00000,ko01000	-	-	-	POR,TPP_enzyme_C
k141_3376_1	937777.Deipe_0520	9.02e-44	166.0	COG0471@1|root,COG0490@1|root,COG0471@2|Bacteria,COG0490@2|Bacteria,1WMCG@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	P	Citrate transporter	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS,TrkA_C
k141_925_2	1396141.BATP01000059_gene2546	3.09e-12	63.9	2CIV9@1|root,34A52@2|Bacteria,46W0H@74201|Verrucomicrobia,2IUYN@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Control of competence regulator ComK, YlbF/YmcA	-	-	-	-	-	-	-	-	-	-	-	-	Com_YlbF
k141_8290_1	990285.RGCCGE502_16880	1.77e-33	118.0	COG0234@1|root,COG0234@2|Bacteria,1MZ2X@1224|Proteobacteria,2U9AQ@28211|Alphaproteobacteria,4BFJE@82115|Rhizobiaceae	28211|Alphaproteobacteria	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	-	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
k141_8290_2	1382359.JIAL01000001_gene1678	2.39e-62	206.0	COG0459@1|root,COG0459@2|Bacteria,3Y37I@57723|Acidobacteria,2JIV1@204432|Acidobacteriia	204432|Acidobacteriia	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	-	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
k141_2777_1	395493.BegalDRAFT_2979	6.23e-18	85.1	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,1RMBS@1236|Gammaproteobacteria,45ZSX@72273|Thiotrichales	72273|Thiotrichales	NU	Type II IV secretion system protein	pilB	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE,T2SSE_N
k141_4010_1	204773.HEAR3184	5.91e-15	79.3	COG0457@1|root,COG0745@1|root,COG0457@2|Bacteria,COG0745@2|Bacteria,1NNCT@1224|Proteobacteria,2VK0Z@28216|Betaproteobacteria,475T4@75682|Oxalobacteraceae	28216|Betaproteobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,TPR_16
k141_3377_1	1286106.MPL1_09707	1.03e-45	149.0	COG0100@1|root,COG0100@2|Bacteria,1RD0A@1224|Proteobacteria,1S3Q2@1236|Gammaproteobacteria,460IQ@72273|Thiotrichales	72273|Thiotrichales	J	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome	rpsK	-	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
k141_3377_2	187272.Mlg_0482	2.71e-80	243.0	COG0522@1|root,COG0522@2|Bacteria,1MW0U@1224|Proteobacteria,1RQ38@1236|Gammaproteobacteria,1WW34@135613|Chromatiales	135613|Chromatiales	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	-	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
k141_1547_1	1123401.JHYQ01000003_gene2167	6.02e-61	198.0	COG4658@1|root,COG4658@2|Bacteria,1MVY6@1224|Proteobacteria,1RMEU@1236|Gammaproteobacteria,45ZZZ@72273|Thiotrichales	72273|Thiotrichales	C	Part of a membrane complex involved in electron transport	-	-	-	ko:K03614	-	-	-	-	ko00000	-	-	-	NQR2_RnfD_RnfE
k141_7093_1	1131813.AQVT01000001_gene2871	9.82e-24	99.0	29Q66@1|root,30B54@2|Bacteria,1N9YZ@1224|Proteobacteria,2TS6J@28211|Alphaproteobacteria,1JSG9@119045|Methylobacteriaceae	28211|Alphaproteobacteria	S	Domain of unknown function (DUF4166)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4166
k141_5859_1	349521.HCH_05222	7.24e-101	301.0	COG1180@1|root,COG1180@2|Bacteria,1NQC1@1224|Proteobacteria,1RW3Z@1236|Gammaproteobacteria,1XI20@135619|Oceanospirillales	135619|Oceanospirillales	O	Pyruvate formate lyase-activating protein	-	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Radical_SAM
k141_2778_1	70448.Q0P3F5	1.26e-98	307.0	COG1007@1|root,KOG4668@2759|Eukaryota,37NNE@33090|Viridiplantae,34KBF@3041|Chlorophyta	3041|Chlorophyta	C	NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus	nad5	-	1.6.5.3	ko:K03883	ko00190,ko01100,ko04714,ko04723,ko05012,map00190,map01100,map04714,map04723,map05012	M00142	R11945	RC00061	ko00000,ko00001,ko00002,ko01000,ko03029	3.D.1.6	-	-	Proton_antipo_M,Proton_antipo_N
k141_928_1	1120953.AUBH01000004_gene3155	6.33e-84	272.0	COG0525@1|root,COG0525@2|Bacteria,1MV7B@1224|Proteobacteria,1RNEB@1236|Gammaproteobacteria,465F9@72275|Alteromonadaceae	1236|Gammaproteobacteria	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	GO:0000287,GO:0002161,GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006417,GO:0006418,GO:0006438,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0016070,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019222,GO:0019538,GO:0019752,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0034248,GO:0034250,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045727,GO:0045903,GO:0046483,GO:0046872,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0052689,GO:0060255,GO:0061475,GO:0065007,GO:0065008,GO:0071704,GO:0080090,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:2000112	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iECH74115_1262.ECH74115_5779,iECNA114_1301.ECNA114_4481,iECO26_1355.ECO26_5428,iECSP_1301.ECSP_5359,iECs_1301.ECs5235,iG2583_1286.G2583_5088,iJN746.PP_0977,iSBO_1134.SBO_4182,iSSON_1240.SSON_4443,iYL1228.KPN_04663,iZ_1308.Z5870	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
k141_4012_1	1535422.ND16A_1363	3.12e-102	315.0	28HMZ@1|root,2Z7WD@2|Bacteria,1MU3Q@1224|Proteobacteria,1RRUM@1236|Gammaproteobacteria,2Q6Y5@267889|Colwelliaceae	1236|Gammaproteobacteria	S	Protein of unknown function (DUF3604)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3604
k141_8901_1	1283284.AZUK01000001_gene1295	4.21e-32	119.0	COG2003@1|root,COG2003@2|Bacteria,1MXZ5@1224|Proteobacteria,1RP86@1236|Gammaproteobacteria,1Y3ZB@135624|Aeromonadales	135624|Aeromonadales	E	Belongs to the UPF0758 family	radC	-	-	ko:K03630	-	-	-	-	ko00000	-	-	-	RadC
k141_8901_2	272624.lpg2488	3.82e-29	115.0	COG0452@1|root,COG0452@2|Bacteria,1MVQP@1224|Proteobacteria,1RMKQ@1236|Gammaproteobacteria,1JCDH@118969|Legionellales	118969|Legionellales	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	dfp	-	4.1.1.36,6.3.2.5	ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
k141_7659_2	717774.Marme_2542	6.23e-64	207.0	COG0104@1|root,COG0104@2|Bacteria,1MU5B@1224|Proteobacteria,1RNEW@1236|Gammaproteobacteria,1XH80@135619|Oceanospirillales	135619|Oceanospirillales	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	-	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
k141_316_1	587753.EY04_00215	6.48e-43	160.0	COG2373@1|root,COG2931@1|root,COG2373@2|Bacteria,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	DUF4214,DUF4347,He_PIG,PATR
k141_4638_2	7739.XP_002590018.1	1.72e-23	95.1	2D0S2@1|root,2SF6P@2759|Eukaryota	2759|Eukaryota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_4013_2	1231391.AMZF01000022_gene1225	3.38e-24	97.4	COG4319@1|root,COG4319@2|Bacteria,1NDE4@1224|Proteobacteria	1224|Proteobacteria	S	Domain of unknown function (DUF4440)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440
k141_6489_1	1352941.M877_02775	1.96e-82	255.0	COG0075@1|root,COG0075@2|Bacteria,2GM5F@201174|Actinobacteria	201174|Actinobacteria	E	Aminotransferase	-	-	2.6.1.44,2.6.1.45,2.6.1.51	ko:K00830	ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146	M00346,M00532	R00369,R00372,R00585,R00588	RC00006,RC00008,RC00018	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
k141_2870_1	1244869.H261_14835	2.93e-112	330.0	COG1077@1|root,COG1077@2|Bacteria,1MUMW@1224|Proteobacteria,2TTQ2@28211|Alphaproteobacteria,2JPHS@204441|Rhodospirillales	204441|Rhodospirillales	D	Rod shape-determining protein MreB	mreB	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
k141_6566_1	472759.Nhal_1736	4.74e-90	271.0	COG0390@1|root,COG0390@2|Bacteria,1MV2N@1224|Proteobacteria,1RSGA@1236|Gammaproteobacteria,1WW8S@135613|Chromatiales	135613|Chromatiales	S	PFAM conserved	-	-	-	ko:K02069	-	M00211	-	-	ko00000,ko00002,ko02000	9.B.25.1	-	-	UPF0014
k141_7747_1	1266908.AQPB01000052_gene702	1.82e-28	111.0	COG2143@1|root,COG2143@2|Bacteria,1R72D@1224|Proteobacteria,1RSDK@1236|Gammaproteobacteria,1WVUU@135613|Chromatiales	135613|Chromatiales	O	Thioredoxin-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_2
k141_7747_2	697282.Mettu_0698	1.36e-32	123.0	COG0304@1|root,COG0304@2|Bacteria,1MU1X@1224|Proteobacteria,1RMDE@1236|Gammaproteobacteria,1XDY1@135618|Methylococcales	135618|Methylococcales	IQ	Belongs to the beta-ketoacyl-ACP synthases family	fabB	-	2.3.1.41	ko:K00647	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
k141_8976_1	768671.ThimaDRAFT_0070	1.29e-75	241.0	COG4942@1|root,COG4942@2|Bacteria,1MXRZ@1224|Proteobacteria,1RR9E@1236|Gammaproteobacteria,1WYAD@135613|Chromatiales	135613|Chromatiales	D	Protein of unknown function (DUF3375)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3375
k141_4102_1	439496.RBY4I_2589	3.23e-44	155.0	COG3246@1|root,COG3246@2|Bacteria,1MXEF@1224|Proteobacteria,2U387@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	beta-keto acid cleavage enzyme	-	-	-	-	-	-	-	-	-	-	-	-	BKACE
k141_7180_1	314265.R2601_10179	3.02e-39	134.0	COG0605@1|root,COG0605@2|Bacteria,1MVW2@1224|Proteobacteria,2TU3T@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	Destroys radicals which are normally produced within the cells and which are toxic to biological systems	sodB	-	1.15.1.1	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Fe_C,Sod_Fe_N
k141_7180_2	1305735.JAFT01000005_gene3427	7.61e-14	70.9	COG2962@1|root,COG2962@2|Bacteria,1MX5G@1224|Proteobacteria,2TV8D@28211|Alphaproteobacteria,2PE0H@252301|Oceanicola	28211|Alphaproteobacteria	S	EamA-like transporter family	rarD	-	-	ko:K05786	-	-	-	-	ko00000,ko02000	2.A.7.7	-	-	EamA
k141_5340_1	991905.SL003B_0087	6.57e-139	410.0	COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,2TRKS@28211|Alphaproteobacteria,4BP7M@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	I	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	acsA	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
k141_3456_2	2850.Phatr37403	4.52e-69	209.0	2BG5J@1|root,2S18N@2759|Eukaryota,2XHTV@2836|Bacillariophyta	2836|Bacillariophyta	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_3456_3	159749.K0SBX2	1.07e-32	114.0	2DZEY@1|root,2S6ZB@2759|Eukaryota	2759|Eukaryota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_9630_1	42565.FP66_02350	1.83e-39	134.0	COG0251@1|root,COG0251@2|Bacteria,1MZ3J@1224|Proteobacteria,1S5XS@1236|Gammaproteobacteria,1XJX9@135619|Oceanospirillales	135619|Oceanospirillales	J	endoribonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
k141_9630_2	247634.GPB2148_720	8.82e-25	104.0	COG1200@1|root,COG1200@2|Bacteria,1MWN2@1224|Proteobacteria,1RMMQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	GO:0003674,GO:0003678,GO:0003724,GO:0003824,GO:0004003,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0008186,GO:0009314,GO:0009379,GO:0009628,GO:0009987,GO:0010501,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051276,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:0140098,GO:1901360,GO:1902494	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
k141_7181_1	1195246.AGRI_01430	5.76e-54	191.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,464X3@72275|Alteromonadaceae	1236|Gammaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran,DUF805
k141_6567_1	472759.Nhal_0523	2.56e-97	295.0	COG0499@1|root,COG0499@2|Bacteria,1MUQ2@1224|Proteobacteria,1RMW8@1236|Gammaproteobacteria,1WVY5@135613|Chromatiales	135613|Chromatiales	H	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine	ahcY	-	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
k141_5947_1	2340.JV46_26680	8.63e-74	232.0	COG1740@1|root,COG1740@2|Bacteria,1MWAC@1224|Proteobacteria,1RNTJ@1236|Gammaproteobacteria,1JB7M@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	NiFe/NiFeSe hydrogenase small subunit C-terminal	-	-	1.12.99.6	ko:K06282	ko00633,ko01120,map00633,map01120	-	R08034	RC00250	ko00000,ko00001,ko01000	-	-	-	NiFe_hyd_SSU_C,Oxidored_q6
k141_9631_1	247633.GP2143_01915	1.25e-76	236.0	COG1028@1|root,COG1028@2|Bacteria,1N4J7@1224|Proteobacteria,1RQ0S@1236|Gammaproteobacteria	1236|Gammaproteobacteria	IQ	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	-	-	1.1.1.175	ko:K22185	ko00040,map00040	-	R01429	RC00066	ko00000,ko00001,ko01000	-	-	-	adh_short_C2
k141_8383_1	391626.OAN307_c25790	2.44e-97	291.0	COG1609@1|root,COG1609@2|Bacteria,1MXQ1@1224|Proteobacteria,2U2CW@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	helix_turn _helix lactose operon repressor	rbtR	-	-	ko:K02529,ko:K03435	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_1,Peripla_BP_4
k141_7182_1	234267.Acid_4075	9.4e-60	202.0	COG4993@1|root,COG4993@2|Bacteria,3Y6WZ@57723|Acidobacteria	57723|Acidobacteria	C	Pyrrolo-quinoline quinone	-	-	1.1.5.2	ko:K00117	ko00030,ko01100,ko01110,ko01130,map00030,map01100,map01110,map01130	-	R06620	RC00066	ko00000,ko00001,ko01000	-	-	-	Cytochrome_CBB3,PQQ,PQQ_2
k141_1639_1	909943.HIMB100_00017020	2.49e-68	215.0	COG1024@1|root,COG1024@2|Bacteria,1MWZC@1224|Proteobacteria,2TRYS@28211|Alphaproteobacteria,4BPKP@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	I	enoyl-CoA hydratase isomerase family	-	-	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
k141_3458_1	1042209.HK44_028090	2.34e-56	186.0	COG3547@1|root,COG3547@2|Bacteria,1MUER@1224|Proteobacteria,1RMAQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k141_2418_1	266809.PM03_01345	7.16e-95	300.0	COG0404@1|root,COG0665@1|root,COG0404@2|Bacteria,COG0665@2|Bacteria,1MUXJ@1224|Proteobacteria,2TRGS@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Belongs to the GcvT family	dmgdh2	-	1.5.8.4	ko:K00315	ko00260,ko01100,map00260,map01100	-	R01565	RC00181	ko00000,ko00001,ko01000	-	-	-	DAO,FAO_M,GCV_T,GCV_T_C
k141_562_1	1229909.NSED_09560	7.15e-137	395.0	COG0446@1|root,arCOG01064@2157|Archaea,41SZR@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.5.4	ko:K17218	ko00920,map00920	-	R10152	RC03155	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
k141_562_2	436308.Nmar_1784	1.89e-11	59.3	arCOG08810@1|root,arCOG08810@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_6113_1	391626.OAN307_c03800	2.52e-121	355.0	COG2826@1|root,COG2826@2|Bacteria,1PP49@1224|Proteobacteria,2TRVA@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	COG2826 Transposase and inactivated derivatives, IS30 family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_38,rve
k141_5500_1	1301098.PKB_0474	3.46e-17	81.3	COG1525@1|root,COG1525@2|Bacteria,1RKRQ@1224|Proteobacteria,1S7UH@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	nuclease	-	-	-	-	-	-	-	-	-	-	-	-	SNase
k141_5500_2	762983.HMPREF9444_01369	9.3e-29	105.0	COG0254@1|root,COG0254@2|Bacteria,1MZ69@1224|Proteobacteria,1SCMH@1236|Gammaproteobacteria,1Y4TI@135624|Aeromonadales	135624|Aeromonadales	J	Binds the 23S rRNA	rpmE	-	-	ko:K02909	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31
k141_7335_1	717774.Marme_2976	1.48e-85	263.0	COG0564@1|root,COG0564@2|Bacteria,1MUBN@1224|Proteobacteria,1RN7F@1236|Gammaproteobacteria,1XHHX@135619|Oceanospirillales	135619|Oceanospirillales	J	Responsible for synthesis of pseudouridine from uracil	rluD	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
k141_4271_1	1046714.AMRX01000008_gene804	8.02e-10	61.6	COG0845@1|root,COG0845@2|Bacteria,1MUFW@1224|Proteobacteria,1RQJ9@1236|Gammaproteobacteria,466HH@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	HlyD_D23
k141_4271_2	1046714.AMRX01000008_gene805	3.41e-48	171.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,4648N@72275|Alteromonadaceae	1236|Gammaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	acrF	-	-	ko:K18138	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
k141_2419_1	857293.CAAU_1898	3.88e-23	95.5	COG2884@1|root,COG2884@2|Bacteria,1TP58@1239|Firmicutes,248HW@186801|Clostridia,36DHJ@31979|Clostridiaceae	186801|Clostridia	D	cell division ATP-binding protein FtsE	ftsE	-	-	ko:K09812	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	ABC_tran
k141_2419_2	998088.B565_3684	5.68e-34	129.0	COG0552@1|root,COG0552@2|Bacteria,1MUDU@1224|Proteobacteria,1RNIN@1236|Gammaproteobacteria,1Y3KZ@135624|Aeromonadales	135624|Aeromonadales	D	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components	ftsY	-	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
k141_3613_1	941449.dsx2_3263	1.56e-64	214.0	COG0166@1|root,COG0166@2|Bacteria,1MUFP@1224|Proteobacteria,42MNB@68525|delta/epsilon subdivisions,2WJ0I@28221|Deltaproteobacteria,2MG34@213115|Desulfovibrionales	28221|Deltaproteobacteria	G	Belongs to the GPI family	pgi	-	5.3.1.9	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI
k141_4880_1	1283284.AZUK01000001_gene591	2.11e-08	61.6	COG3344@1|root,COG3344@2|Bacteria,1MVI1@1224|Proteobacteria,1RQP7@1236|Gammaproteobacteria,1Y6AP@135624|Aeromonadales	135624|Aeromonadales	L	Group II intron, maturase-specific domain	-	-	-	-	-	-	-	-	-	-	-	-	GIIM,RVT_1
k141_8545_1	1246459.KB898362_gene3330	3.77e-24	100.0	COG0154@1|root,COG0154@2|Bacteria,1MUVQ@1224|Proteobacteria,2TRFY@28211|Alphaproteobacteria,4B9SV@82115|Rhizobiaceae	28211|Alphaproteobacteria	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
k141_8545_2	1123237.Salmuc_01107	5.24e-95	290.0	COG0154@1|root,COG0154@2|Bacteria,1MUVQ@1224|Proteobacteria,2TRFY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
k141_3033_1	1121106.JQKB01000028_gene4234	1.8e-31	120.0	COG0462@1|root,COG0462@2|Bacteria,1MW21@1224|Proteobacteria,2TR4Y@28211|Alphaproteobacteria,2JPJR@204441|Rhodospirillales	204441|Rhodospirillales	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	prs	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran,Pribosyltran_N
k141_4272_1	391624.OIHEL45_16936	6.94e-52	175.0	COG2148@1|root,COG2148@2|Bacteria,1MV6W@1224|Proteobacteria,2U7DN@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	COG2148 Sugar transferases involved in lipopolysaccharide synthesis	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf
k141_6730_1	571166.KI421510_gene288	3.1e-138	412.0	COG3451@1|root,COG3451@2|Bacteria,1MXH0@1224|Proteobacteria,2TR1U@28211|Alphaproteobacteria	28211|Alphaproteobacteria	U	type IV secretion	-	-	-	ko:K03199	ko03070,map03070	M00333	-	-	ko00000,ko00001,ko00002,ko02044	3.A.7	-	-	AAA_10,CagE_TrbE_VirB
k141_7337_1	1288298.rosmuc_00995	3.02e-97	284.0	COG1764@1|root,COG1764@2|Bacteria,1RHVR@1224|Proteobacteria,2U7CX@28211|Alphaproteobacteria,46NPJ@74030|Roseovarius	28211|Alphaproteobacteria	O	redox protein, regulator of disulfide bond formation	-	-	-	-	-	-	-	-	-	-	-	-	OsmC
k141_4881_1	754477.Q7C_1737	1.03e-97	291.0	COG0115@1|root,COG0115@2|Bacteria,1MVB0@1224|Proteobacteria,1RP6Z@1236|Gammaproteobacteria,4603P@72273|Thiotrichales	72273|Thiotrichales	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
k141_8546_1	413404.Rmag_0859	3.68e-93	283.0	COG5557@1|root,COG5557@2|Bacteria,1MXP7@1224|Proteobacteria,1SMKH@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Polysulphide reductase, NrfD	-	-	-	ko:K00185	-	-	-	-	ko00000	5.A.3	-	-	NrfD
k141_6731_1	391613.RTM1035_05943	3.24e-102	322.0	COG0403@1|root,COG1003@1|root,COG0403@2|Bacteria,COG1003@2|Bacteria,1MUDP@1224|Proteobacteria,2TSFF@28211|Alphaproteobacteria,46QJB@74030|Roseovarius	28211|Alphaproteobacteria	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvP	-	1.4.4.2	ko:K00281,ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko00002,ko01000	-	-	-	Aminotran_5,GDC-P
k141_4882_1	1123517.JOMR01000001_gene1183	2.66e-40	152.0	COG0471@1|root,COG0471@2|Bacteria,1MU0K@1224|Proteobacteria,1RMI1@1236|Gammaproteobacteria,462HB@72273|Thiotrichales	72273|Thiotrichales	P	Sodium:sulfate symporter transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS,TrkA_C
k141_3035_1	1229909.NSED_04520	3.92e-105	312.0	arCOG03562@1|root,arCOG03562@2157|Archaea,41SY7@651137|Thaumarchaeota	651137|Thaumarchaeota	O	AhpC/TSA family	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
k141_9138_1	1238182.C882_2938	6.34e-46	152.0	COG0222@1|root,COG0222@2|Bacteria,1RGU4@1224|Proteobacteria,2U9FX@28211|Alphaproteobacteria,2JSU1@204441|Rhodospirillales	204441|Rhodospirillales	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation	rplL	-	-	ko:K02935	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L12,Ribosomal_L12_N
k141_9138_2	1121123.AUAO01000003_gene2292	7.19e-05	44.7	COG0244@1|root,COG0244@2|Bacteria,1RAN5@1224|Proteobacteria,2U592@28211|Alphaproteobacteria,2KG8X@204458|Caulobacterales	204458|Caulobacterales	J	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors	rplJ	-	-	ko:K02864	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L10
k141_6116_1	1535287.JP74_08845	5.97e-08	55.5	COG3191@1|root,COG3191@2|Bacteria,1MWDP@1224|Proteobacteria,2TUI2@28211|Alphaproteobacteria,3N8AD@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	EQ	Peptidase family S58	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S58
k141_6116_2	1121935.AQXX01000078_gene1557	2.41e-15	80.5	COG3127@1|root,COG3127@2|Bacteria,1MU9R@1224|Proteobacteria,1RM8Y@1236|Gammaproteobacteria,1XHVX@135619|Oceanospirillales	135619|Oceanospirillales	Q	ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	-
k141_4883_1	13689.BV96_02131	1.85e-29	115.0	COG0604@1|root,COG0604@2|Bacteria,1MWBD@1224|Proteobacteria,2U2WR@28211|Alphaproteobacteria,2K0RJ@204457|Sphingomonadales	204457|Sphingomonadales	C	Zinc-binding dehydrogenase	-	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N,ADH_zinc_N_2
k141_5504_1	1123237.Salmuc_03791	1.26e-95	293.0	COG1008@1|root,COG1008@2|Bacteria,1MV7V@1224|Proteobacteria,2TSNK@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	NADH ubiquinone oxidoreductase subunit 4 (chain M)	nuoM	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q5_N,Proton_antipo_M
k141_7908_1	118166.JH976537_gene4619	5.54e-59	192.0	COG1234@1|root,COG1234@2|Bacteria	2|Bacteria	L	tRNA 3'-trailer cleavage	-	-	3.1.26.11	ko:K00784	ko03013,map03013	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	Lactamase_B_2
k141_2422_2	159749.E7BWI9	2.93e-122	362.0	COG0056@1|root,KOG1353@2759|Eukaryota,2XEPU@2836|Bacillariophyta	2836|Bacillariophyta	F	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	-	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
k141_6732_1	1123237.Salmuc_04823	2.03e-121	359.0	COG3278@1|root,COG3278@2|Bacteria,1MU18@1224|Proteobacteria,2TR2C@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Belongs to the heme-copper respiratory oxidase family	ccoN	GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015672,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0022900,GO:0022904,GO:0034220,GO:0044237,GO:0044464,GO:0045333,GO:0051179,GO:0051234,GO:0055085,GO:0055114,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:1902600	1.9.3.1	ko:K00404	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	COX1
k141_5586_1	159749.K0T6U0	1.77e-54	194.0	COG2801@1|root,2QT1S@2759|Eukaryota	2759|Eukaryota	L	transposition	-	-	-	-	-	-	-	-	-	-	-	-	RVT_1,rve
k141_3122_1	404589.Anae109_0189	6.15e-60	211.0	COG1924@1|root,COG3580@1|root,COG3581@1|root,COG1924@2|Bacteria,COG3580@2|Bacteria,COG3581@2|Bacteria,1PKG6@1224|Proteobacteria,42MY4@68525|delta/epsilon subdivisions,2WJFI@28221|Deltaproteobacteria,2YVGM@29|Myxococcales	28221|Deltaproteobacteria	I	CoA-substrate-specific enzyme activase	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG,DUF2229
k141_8042_1	159749.E7BWJ0	3.1e-18	81.6	COG0335@1|root,KOG1698@2759|Eukaryota,2XFXY@2836|Bacillariophyta	2836|Bacillariophyta	J	Ribosomal protein L19	-	GO:0000313,GO:0000315,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005761,GO:0005762,GO:0005840,GO:0009507,GO:0009536,GO:0015934,GO:0031974,GO:0032991,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044391,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0070013,GO:0098798,GO:1990904	-	-	-	-	-	-	-	-	-	-	Ribosomal_L19
k141_40_1	1499967.BAYZ01000113_gene2944	1.71e-100	302.0	COG0050@1|root,COG0050@2|Bacteria,2NNQV@2323|unclassified Bacteria	2|Bacteria	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
k141_1889_1	1026882.MAMP_03108	6.33e-30	116.0	COG0849@1|root,COG0849@2|Bacteria,1MUSR@1224|Proteobacteria,1RMXY@1236|Gammaproteobacteria,46048@72273|Thiotrichales	72273|Thiotrichales	D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring	ftsA	-	-	ko:K03590	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036,ko04812	-	-	-	FtsA,SHS2_FTSA
k141_1889_2	765912.Thimo_3105	1.92e-46	160.0	COG0206@1|root,COG0206@2|Bacteria,1MV2X@1224|Proteobacteria,1RPZS@1236|Gammaproteobacteria,1WXJ6@135613|Chromatiales	135613|Chromatiales	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
k141_656_1	913325.N799_13260	9.19e-44	157.0	COG2010@1|root,COG2132@1|root,COG2010@2|Bacteria,COG2132@2|Bacteria,1MV74@1224|Proteobacteria,1RXZF@1236|Gammaproteobacteria,1X3IK@135614|Xanthomonadales	135614|Xanthomonadales	CQ	Multicopper oxidase	-	-	1.7.2.1	ko:K00368	ko00910,ko01120,map00910,map01120	M00529	R00783,R00785	RC00086	ko00000,ko00001,ko00002,ko01000	-	-	-	Cu-oxidase,Cu-oxidase_3,Cytochrome_CBB3
k141_3737_1	412597.AEPN01000003_gene3359	0.000206	41.6	COG1872@1|root,COG1872@2|Bacteria,1PURW@1224|Proteobacteria,2V4QN@28211|Alphaproteobacteria,2PXMN@265|Paracoccus	28211|Alphaproteobacteria	S	DUF167	-	-	-	ko:K09131	-	-	-	-	ko00000	-	-	-	DUF167
k141_3737_2	89187.ISM_11545	1.33e-28	104.0	2CNWN@1|root,32SHY@2|Bacteria,1MZMG@1224|Proteobacteria,2UCKI@28211|Alphaproteobacteria,46R4R@74030|Roseovarius	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_8661_1	631362.Thi970DRAFT_04763	4.23e-92	280.0	COG0330@1|root,COG0330@2|Bacteria,1MV7R@1224|Proteobacteria,1RMF2@1236|Gammaproteobacteria,1X0ZR@135613|Chromatiales	135613|Chromatiales	O	HflC and HflK could regulate a protease	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
k141_4971_1	1121875.KB907549_gene2005	5.77e-112	346.0	COG1882@1|root,COG1882@2|Bacteria,4NDWW@976|Bacteroidetes,1I0UR@117743|Flavobacteriia	976|Bacteroidetes	C	Pyruvate formate lyase-like	-	-	2.3.1.54,4.1.1.83	ko:K00656,ko:K18427	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	-	R00212,R06987	RC00004,RC01181,RC02742,RC02833	ko00000,ko00001,ko01000	-	-	-	Gly_radical,PFL-like
k141_6819_1	159749.K0SIV8	3.75e-29	106.0	2E0DG@1|root,2S7U6@2759|Eukaryota,2XHN2@2836|Bacillariophyta	2836|Bacillariophyta	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_6819_2	7029.ACYPI073473-PA	0.000381	43.5	2EA4H@1|root,2SZ18@2759|Eukaryota,38VIS@33154|Opisthokonta,3C5X1@33208|Metazoa,3DR66@33213|Bilateria,428IV@6656|Arthropoda,3SSBM@50557|Insecta	7029.ACYPI073473-PA|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_4360_1	118161.KB235922_gene4468	6.65e-32	129.0	COG0072@1|root,COG0072@2|Bacteria,1G0AT@1117|Cyanobacteria,3VIPX@52604|Pleurocapsales	1117|Cyanobacteria	J	TIGRFAM phenylalanyl-tRNA synthetase, beta subunit, non-spirochete bacterial	pheT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
k141_1891_1	1249997.JHZW01000002_gene892	2.73e-109	342.0	COG4447@1|root,COG4447@2|Bacteria,4NESU@976|Bacteroidetes,1HXIG@117743|Flavobacteriia,2PG13@252356|Maribacter	976|Bacteroidetes	S	Sortilin, neurotensin receptor 3,	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
k141_3738_1	1229909.NSED_05785	5.98e-12	61.2	arCOG10569@1|root,arCOG10569@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_3738_3	1229909.NSED_06005	9.87e-25	99.4	arCOG03042@1|root,arCOG03042@2157|Archaea	2157|Archaea	KLT	PFAM Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_16,TPR_2,TPR_8
k141_1278_1	744980.TRICHSKD4_4797	1.22e-46	168.0	COG0330@1|root,COG0330@2|Bacteria,1MW1D@1224|Proteobacteria,2TRE5@28211|Alphaproteobacteria	28211|Alphaproteobacteria	O	SPFH domain / Band 7 family	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
k141_43_1	314264.ROS217_16381	9.65e-61	197.0	COG0697@1|root,COG0697@2|Bacteria,1NDKG@1224|Proteobacteria,2U0DF@28211|Alphaproteobacteria,46NV9@74030|Roseovarius	28211|Alphaproteobacteria	EG	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily	-	-	-	-	-	-	-	-	-	-	-	-	EamA
k141_8662_1	479434.Sthe_2777	1.14e-22	92.4	COG2080@1|root,COG2080@2|Bacteria,2GBCT@200795|Chloroflexi,27YT4@189775|Thermomicrobia	189775|Thermomicrobia	C	2Fe-2S -binding domain protein	-	-	1.2.5.3	ko:K03518	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Fer2_2
k141_8662_2	457415.HMPREF1006_00496	1.8e-06	52.4	COG1529@1|root,COG1529@2|Bacteria,3TA0C@508458|Synergistetes	508458|Synergistetes	C	aldehyde oxidase and xanthine dehydrogenase a b hammerhead	-	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
k141_6820_2	1123367.C666_04165	4.61e-35	126.0	COG3663@1|root,COG3663@2|Bacteria,1REPV@1224|Proteobacteria,2VRAT@28216|Betaproteobacteria,2KWSB@206389|Rhodocyclales	206389|Rhodocyclales	L	G T U mismatch-specific DNA glycosylase	mug	-	-	-	-	-	-	-	-	-	-	-	UDG
k141_5591_1	713587.THITH_14555	1.06e-65	214.0	COG1290@1|root,COG1290@2|Bacteria,1MV97@1224|Proteobacteria,1RNCP@1236|Gammaproteobacteria,1WWQP@135613|Chromatiales	135613|Chromatiales	C	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis	petB	-	-	ko:K00412	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002,ko03029	-	-	-	Cytochrom_B_C,Cytochrome_B
k141_8044_1	391619.PGA1_c23130	4.14e-184	519.0	COG0006@1|root,COG0006@2|Bacteria,1MVX5@1224|Proteobacteria,2TRMK@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Xaa-Pro aminopeptidase	-	-	3.4.13.9	ko:K01271	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Creatinase_N,Peptidase_M24
k141_6207_2	1073999.BN137_2538	4e-17	82.0	COG3209@1|root,COG3209@2|Bacteria,1MVV1@1224|Proteobacteria,1SKYM@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	COG3209 Rhs family protein	-	-	-	-	-	-	-	-	-	-	-	-	RHS,RHS_repeat
k141_7428_1	391595.RLO149_p630100	1.91e-59	188.0	COG3293@1|root,COG3293@2|Bacteria,1QXE6@1224|Proteobacteria,2TX8K@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_2
k141_1893_1	748247.AZKH_0280	5.04e-29	116.0	COG0204@1|root,COG0204@2|Bacteria,1MWDY@1224|Proteobacteria,2VJ4I@28216|Betaproteobacteria,2KV3W@206389|Rhodocyclales	206389|Rhodocyclales	I	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase,MFS_1
k141_4362_1	1342301.JASD01000008_gene1300	1.15e-121	349.0	COG0127@1|root,COG0127@2|Bacteria,1MUK5@1224|Proteobacteria,2TV4B@28211|Alphaproteobacteria,3ZUU7@60136|Sulfitobacter	28211|Alphaproteobacteria	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions	rdgB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	Ham1p_like
k141_3125_1	1089552.KI911559_gene3324	1.04e-30	124.0	COG1148@1|root,COG1148@2|Bacteria,1QUQG@1224|Proteobacteria,2TWJ4@28211|Alphaproteobacteria,2JYYR@204441|Rhodospirillales	204441|Rhodospirillales	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4
k141_660_1	371731.Rsw2DRAFT_0369	4.98e-96	295.0	COG1328@1|root,COG1328@2|Bacteria,1N1EN@1224|Proteobacteria,2TU2D@28211|Alphaproteobacteria	28211|Alphaproteobacteria	F	Protein of unknown function (DUF3029)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3029
k141_1894_1	384765.SIAM614_02606	1.39e-83	257.0	COG2367@1|root,COG2367@2|Bacteria,1NMW4@1224|Proteobacteria,2UBDH@28211|Alphaproteobacteria	28211|Alphaproteobacteria	V	Beta-lactamase	-	-	3.5.2.6	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	M00627,M00628	R06363	RC01499	ko00000,ko00001,ko00002,ko01000,ko01504	-	-	-	Beta-lactamase2,Peptidase_S13
k141_8045_1	314271.RB2654_17346	5.6e-152	431.0	COG0074@1|root,COG0074@2|Bacteria,1MUGA@1224|Proteobacteria,2TQKB@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit	sucD	-	6.2.1.5	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_binding,Ligase_CoA
k141_4974_1	1380384.JADN01000006_gene2580	2.11e-75	234.0	COG1878@1|root,COG1878@2|Bacteria,4NFYB@976|Bacteroidetes,1IIVK@117743|Flavobacteriia	976|Bacteroidetes	S	Putative cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Cyclase
k141_9292_1	35128.Thapsdraft2073	9.34e-175	498.0	28JG1@1|root,2QRV6@2759|Eukaryota,2XEM0@2836|Bacillariophyta	2836|Bacillariophyta	P	One of the components of the core complex of photosystem II (PSII). It binds chlorophyll and helps catalyze the primary light-induced photochemical processes of PSII. PSII is a light- driven water plastoquinone oxidoreductase, using light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation	psbB	-	-	ko:K02704	ko00195,ko01100,map00195,map01100	M00161	-	-	ko00000,ko00001,ko00002,ko00194	-	-	-	PSII
k141_3127_1	398578.Daci_4903	1.24e-07	55.5	COG2812@1|root,COG2812@2|Bacteria,1MVCK@1224|Proteobacteria,2VIE0@28216|Betaproteobacteria,4ABHQ@80864|Comamonadaceae	28216|Betaproteobacteria	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3,DNA_pol3_tau_5
k141_1282_1	488538.SAR116_0767	6.49e-61	197.0	COG5285@1|root,COG5285@2|Bacteria,1R6VR@1224|Proteobacteria,2U42H@28211|Alphaproteobacteria,4BQR5@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	Q	Phytanoyl-CoA dioxygenase (PhyH)	-	-	-	-	-	-	-	-	-	-	-	-	PhyH
k141_47_1	1342299.Z947_3907	8.17e-82	266.0	COG0404@1|root,COG0665@1|root,COG0404@2|Bacteria,COG0665@2|Bacteria,1MUXJ@1224|Proteobacteria,2TRGS@28211|Alphaproteobacteria,3ZYAD@60136|Sulfitobacter	28211|Alphaproteobacteria	E	Sarcosine oxidase, gamma subunit family	Sardh	GO:0000166,GO:0001505,GO:0003674,GO:0003824,GO:0005488,GO:0005542,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006082,GO:0006520,GO:0006575,GO:0006576,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008480,GO:0009056,GO:0009063,GO:0009308,GO:0009310,GO:0009987,GO:0016054,GO:0016491,GO:0016645,GO:0019695,GO:0019752,GO:0019842,GO:0031406,GO:0031974,GO:0033218,GO:0034641,GO:0035999,GO:0036094,GO:0042133,GO:0042135,GO:0042219,GO:0042402,GO:0042426,GO:0042558,GO:0043167,GO:0043168,GO:0043177,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043603,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046395,GO:0046483,GO:0046653,GO:0046997,GO:0048037,GO:0050660,GO:0050662,GO:0051186,GO:0055114,GO:0065007,GO:0065008,GO:0070013,GO:0071704,GO:0072341,GO:0097159,GO:0097164,GO:1901052,GO:1901053,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	1.5.3.19	ko:K19191	ko00760,ko01120,map00760,map01120	-	R10102	RC00060,RC00557	ko00000,ko00001,ko01000	-	-	-	DAO,FAO_M,GCV_T,GCV_T_C
k141_9293_1	765910.MARPU_03940	3.45e-111	321.0	COG0717@1|root,COG0717@2|Bacteria,1MV2J@1224|Proteobacteria,1RMCD@1236|Gammaproteobacteria,1WW5U@135613|Chromatiales	135613|Chromatiales	F	Belongs to the dCTP deaminase family	dcd	-	3.5.4.13	ko:K01494	ko00240,ko01100,map00240,map01100	M00053	R00568,R02325	RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	DCD,dUTPase
k141_2514_1	754477.Q7C_2282	2.94e-99	300.0	COG0452@1|root,COG0452@2|Bacteria,1MVQP@1224|Proteobacteria,1RMKQ@1236|Gammaproteobacteria,46038@72273|Thiotrichales	72273|Thiotrichales	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	-	-	4.1.1.36,6.3.2.5	ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
k141_7430_1	1123393.KB891333_gene2641	2.47e-93	299.0	COG0577@1|root,COG0577@2|Bacteria,1MW6D@1224|Proteobacteria,2VKF8@28216|Betaproteobacteria,1KSFY@119069|Hydrogenophilales	119069|Hydrogenophilales	V	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX
k141_2621_1	633131.TR2A62_2358	2.02e-13	65.1	COG1917@1|root,COG1917@2|Bacteria,1N7QJ@1224|Proteobacteria,2UFRZ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	PFAM Cupin 2 conserved barrel domain protein	MA20_03790	-	-	ko:K21700	-	-	-	-	ko00000	-	-	-	Cupin_2
k141_2621_2	1294273.roselon_03390	9.65e-67	216.0	COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,2TQND@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.18	ko:K00822	ko00280,ko00410,ko00640,ko01100,map00280,map00410,map00640,map01100	-	R00907,R04187	RC00008,RC00062,RC00160	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_3
k141_3226_1	1479237.JMLY01000001_gene2703	2.58e-89	272.0	COG2933@1|root,COG2933@2|Bacteria,1MWBM@1224|Proteobacteria,1RMSB@1236|Gammaproteobacteria,4643K@72275|Alteromonadaceae	1236|Gammaproteobacteria	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily	rlmM	GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070677,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.186	ko:K06968	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ
k141_6324_1	519989.ECTPHS_14004	1.35e-12	68.9	COG3344@1|root,COG3344@2|Bacteria,1MVI1@1224|Proteobacteria,1RQP7@1236|Gammaproteobacteria,1WVZP@135613|Chromatiales	135613|Chromatiales	L	reverse transcriptase	-	-	-	-	-	-	-	-	-	-	-	-	RVT_1
k141_145_1	1238182.C882_1088	5.55e-66	202.0	COG0347@1|root,COG0347@2|Bacteria,1RGWK@1224|Proteobacteria,2U73Z@28211|Alphaproteobacteria,2JS4R@204441|Rhodospirillales	204441|Rhodospirillales	K	Belongs to the P(II) protein family	glnB	GO:0003674,GO:0006808,GO:0008150,GO:0030234,GO:0050789,GO:0050790,GO:0065007,GO:0065009,GO:0098772	-	ko:K04751	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	P-II
k141_145_2	1279038.KB907339_gene1416	9.42e-39	141.0	COG0174@1|root,COG0174@2|Bacteria,1MUGQ@1224|Proteobacteria,2TSCR@28211|Alphaproteobacteria,2JPN8@204441|Rhodospirillales	204441|Rhodospirillales	E	glutamine synthetase	glnA	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
k141_5086_1	1415778.JQMM01000001_gene818	4.22e-112	335.0	COG0174@1|root,COG0174@2|Bacteria,1MUGQ@1224|Proteobacteria,1RMD1@1236|Gammaproteobacteria,1J4KI@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	E	glutamine synthetase	glnA	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	iJN746.PP_5046	Gln-synt_C,Gln-synt_N
k141_8750_2	1163617.SCD_n00081	2.67e-34	127.0	COG0189@1|root,COG0189@2|Bacteria,1MVUA@1224|Proteobacteria,2VIZ3@28216|Betaproteobacteria	28216|Betaproteobacteria	H	Belongs to the prokaryotic GSH synthase family	gshB	-	6.3.2.3	ko:K01920	ko00270,ko00480,ko01100,map00270,map00480,map01100	M00118	R00497,R10994	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	GSH-S_ATP,GSH-S_N
k141_3845_1	91464.S7335_4991	7.66e-78	245.0	COG2421@1|root,COG2421@2|Bacteria,1G2PU@1117|Cyanobacteria,1GZVX@1129|Synechococcus	1117|Cyanobacteria	C	Acetamidase/Formamidase family	-	-	3.5.1.49	ko:K01455	ko00460,ko00630,ko00910,ko01200,map00460,map00630,map00910,map01200	-	R00524	RC02432,RC02810	ko00000,ko00001,ko01000	-	-	-	FmdA_AmdA
k141_4473_1	1333998.M2A_0511	8.46e-100	314.0	COG0525@1|root,COG0525@2|Bacteria,1MV7B@1224|Proteobacteria,2TS9E@28211|Alphaproteobacteria,4BPCE@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
k141_2008_1	864051.BurJ1DRAFT_3700	1.36e-14	80.9	COG0726@1|root,COG0823@1|root,COG2911@1|root,COG2931@1|root,COG3210@1|root,COG3420@1|root,COG0726@2|Bacteria,COG0823@2|Bacteria,COG2911@2|Bacteria,COG2931@2|Bacteria,COG3210@2|Bacteria,COG3420@2|Bacteria,1MU7T@1224|Proteobacteria,2WI67@28216|Betaproteobacteria,1KMDS@119065|unclassified Burkholderiales	28216|Betaproteobacteria	MQU	Domain of unknown function (DUF4347)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4347
k141_2623_1	314345.SPV1_03033	2.19e-25	101.0	COG1432@1|root,COG1432@2|Bacteria,1MX5C@1224|Proteobacteria	1224|Proteobacteria	T	OST-HTH/LOTUS domain	-	-	-	-	-	-	-	-	-	-	-	-	NYN,OST-HTH
k141_7509_1	10228.TriadP63021	1.81e-31	123.0	COG0072@1|root,KOG2472@2759|Eukaryota,3A7RT@33154|Opisthokonta,3BXEE@33208|Metazoa	33208|Metazoa	J	phenylalanine--tRNA ligase beta	-	-	-	-	-	-	-	-	-	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
k141_3228_1	765912.Thimo_1854	3.67e-11	63.5	COG0475@1|root,COG0475@2|Bacteria,1QTSD@1224|Proteobacteria,1T1FK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	Sodium hydrogen exchanger	-	-	-	ko:K03455	-	-	-	-	ko00000	2.A.37	-	-	Na_H_Exchanger
k141_5699_1	1415779.JOMH01000001_gene2452	2.42e-22	93.6	COG0811@1|root,COG0811@2|Bacteria,1PKF8@1224|Proteobacteria,1RRWP@1236|Gammaproteobacteria,1X605@135614|Xanthomonadales	135614|Xanthomonadales	U	MotA/TolQ/ExbB proton channel family	-	-	-	-	-	-	-	-	-	-	-	-	MotA_ExbB
k141_6326_1	1237149.C900_03169	5.7e-57	187.0	COG2159@1|root,COG2159@2|Bacteria,4NG9U@976|Bacteroidetes,47MDV@768503|Cytophagia	976|Bacteroidetes	S	PFAM Amidohydrolase 2	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
k141_147_1	595494.Tola_1848	1.85e-100	309.0	COG0511@1|root,COG5016@1|root,COG0511@2|Bacteria,COG5016@2|Bacteria,1QTTG@1224|Proteobacteria,1RNG6@1236|Gammaproteobacteria,1Y6CQ@135624|Aeromonadales	135624|Aeromonadales	C	Conserved carboxylase domain	-	-	6.4.1.1	ko:K01960	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	M00173,M00620	R00344	RC00040,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_lipoyl,HMGL-like,PYC_OADA
k141_2624_1	1121106.JQKB01000050_gene3792	1.27e-19	89.7	COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,2TXJ2@28211|Alphaproteobacteria,2JPEA@204441|Rhodospirillales	204441|Rhodospirillales	T	Histidine kinase	-	-	2.7.13.3	ko:K10715	ko02020,ko02024,map02020,map02024	M00517	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,Hpt,Response_reg
k141_2624_2	713586.KB900536_gene2212	3.42e-25	105.0	COG5002@1|root,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,1T1JE@1236|Gammaproteobacteria,1X2QR@135613|Chromatiales	135613|Chromatiales	T	Histidine Phosphotransfer domain	-	-	2.7.13.3	ko:K10715	ko02020,ko02024,map02020,map02024	M00517	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,Hpt,Response_reg
k141_4475_1	1116375.VEJY3_04050	3.08e-97	296.0	COG1680@1|root,COG1680@2|Bacteria,1MY01@1224|Proteobacteria,1RNUI@1236|Gammaproteobacteria,1XZIB@135623|Vibrionales	135623|Vibrionales	V	Beta-lactamase	-	-	3.5.2.6	ko:K01467	ko01501,ko02020,map01501,map02020	M00628	R06363	RC01499	ko00000,ko00001,ko00002,ko01000	-	-	-	Beta-lactamase
k141_7510_1	765913.ThidrDRAFT_0380	5.79e-18	89.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RRXX@1236|Gammaproteobacteria,1WXC2@135613|Chromatiales	135613|Chromatiales	T	response regulator receiver	-	-	-	ko:K13599	ko02020,map02020	M00498	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
k141_3230_1	1232683.ADIMK_3475	3.53e-97	291.0	COG0601@1|root,COG0601@2|Bacteria,1MWXF@1224|Proteobacteria,1RSBZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
k141_5090_1	95619.PM1_0224510	1.39e-20	95.9	COG2911@1|root,COG2931@1|root,COG2982@1|root,COG2911@2|Bacteria,COG2931@2|Bacteria,COG2982@2|Bacteria,1MU7T@1224|Proteobacteria,1RNK8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	COG2931 RTX toxins and related Ca2 -binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	DUF4214,DUF4347,He_PIG,HemolysinCabind,PA14,VWA_2
k141_4476_1	1410620.SHLA_15c000840	2.19e-41	152.0	COG5362@1|root,COG5410@1|root,COG5362@2|Bacteria,COG5410@2|Bacteria,1NKZK@1224|Proteobacteria,2U0EG@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	TIGRFAM Phage	-	-	-	-	-	-	-	-	-	-	-	-	Terminase_6C
k141_5701_1	1318628.MARLIPOL_10111	3.75e-55	192.0	COG2133@1|root,COG2133@2|Bacteria,1MV2E@1224|Proteobacteria,1RNGN@1236|Gammaproteobacteria,465UX@72275|Alteromonadaceae	1236|Gammaproteobacteria	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3,GSDH
k141_3848_2	478741.JAFS01000001_gene1408	1.39e-65	209.0	COG1940@1|root,COG1940@2|Bacteria,46T0E@74201|Verrucomicrobia	74201|Verrucomicrobia	GK	PFAM ROK family protein	-	-	-	-	-	-	-	-	-	-	-	-	ROK
k141_5091_2	1537994.JQFW01000014_gene1205	1.49e-10	65.1	COG3118@1|root,COG3118@2|Bacteria	2|Bacteria	O	belongs to the thioredoxin family	celD	-	-	ko:K20444,ko:K20543	-	-	-	-	ko00000,ko01000,ko01005,ko02000	1.B.55.3,4.D.1.3	GT2,GT4	-	Acetyltransf_6,BCSC_C,Glyco_transf_41,TPR_16
k141_6941_1	1122176.KB903531_gene2867	9.71e-114	347.0	COG1506@1|root,COG1506@2|Bacteria,4NF70@976|Bacteroidetes	976|Bacteroidetes	EU	Dipeptidyl peptidase IV (DPP IV) N-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	DPPIV_N,Peptidase_S9
k141_773_1	314278.NB231_14788	3.71e-84	268.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,1RPCU@1236|Gammaproteobacteria,1WWF4@135613|Chromatiales	135613|Chromatiales	S	ABC transporter	-	-	-	ko:K15738	-	-	-	-	ko00000,ko02000	3.A.1.120.6	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
k141_4478_1	768671.ThimaDRAFT_0873	3.29e-20	90.5	COG3653@1|root,COG3653@2|Bacteria,1MWWY@1224|Proteobacteria,1TFGB@1236|Gammaproteobacteria,1X1MI@135613|Chromatiales	135613|Chromatiales	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
k141_6330_1	1120999.JONM01000016_gene228	8.87e-15	75.5	COG4254@1|root,COG4254@2|Bacteria,1MYBD@1224|Proteobacteria,2VSSC@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Sporulation related domain	-	-	-	-	-	-	-	-	-	-	-	-	FecR,SPOR
k141_9410_1	765910.MARPU_16735	1.63e-74	240.0	COG0706@1|root,COG0706@2|Bacteria,1MV5M@1224|Proteobacteria,1RMH1@1236|Gammaproteobacteria,1WWKE@135613|Chromatiales	135613|Chromatiales	U	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins	yidC	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP,YidC_periplas
k141_2628_1	697282.Mettu_2580	1.1e-116	352.0	COG1138@1|root,COG1138@2|Bacteria,1MUQS@1224|Proteobacteria,1RMY5@1236|Gammaproteobacteria,1XEQK@135618|Methylococcales	135618|Methylococcales	O	Cytochrome c-type biogenesis protein CcmF	ccmF	-	-	ko:K02198	-	-	-	-	ko00000,ko02000	9.B.14.1	-	-	CcmF_C,Cytochrom_C_asm
k141_6942_1	1298608.JCM18900_11705	6.04e-93	283.0	COG4638@1|root,COG4638@2|Bacteria,1MWXW@1224|Proteobacteria,1S02J@1236|Gammaproteobacteria,3NT7A@468|Moraxellaceae	1236|Gammaproteobacteria	P	Ring hydroxylating alpha subunit (catalytic domain)	-	-	1.14.15.7	ko:K00499	ko00260,map00260	-	R07409	RC00087	ko00000,ko00001,ko01000	-	-	-	Rieske,Ring_hydroxyl_A
k141_7016_1	247634.GPB2148_990	5.16e-98	303.0	28HMZ@1|root,2Z7WD@2|Bacteria,1MU3Q@1224|Proteobacteria,1RRUM@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF3604)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3604
k141_7578_1	240016.ABIZ01000001_gene352	5.15e-81	252.0	COG0133@1|root,COG0133@2|Bacteria,46SHR@74201|Verrucomicrobia,2ITRB@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	-	-	4.2.1.20	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
k141_2083_1	472759.Nhal_1619	1.2e-138	420.0	COG0243@1|root,COG3383@1|root,COG0243@2|Bacteria,COG3383@2|Bacteria,1MW3N@1224|Proteobacteria,1RN6N@1236|Gammaproteobacteria,1X01G@135613|Chromatiales	135613|Chromatiales	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
k141_1464_1	159749.K0RL31	2.56e-39	148.0	COG2801@1|root,KOG0017@2759|Eukaryota,2XF4I@2836|Bacillariophyta	159749.K0RL31|-	L	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_5170_1	35128.Thapsdraft1339	1.77e-92	270.0	28I81@1|root,2QQIC@2759|Eukaryota,2XFIZ@2836|Bacillariophyta	2836|Bacillariophyta	S	PsaD	psaD	-	-	ko:K02692	ko00195,ko01100,map00195,map01100	M00163	-	-	ko00000,ko00001,ko00002,ko00194	-	-	-	PsaD
k141_3925_1	349521.HCH_03020	2.91e-83	272.0	COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,1SP6I@1236|Gammaproteobacteria,1XHSN@135619|Oceanospirillales	135619|Oceanospirillales	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K07787	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4	-	-	ACR_tran
k141_227_1	338969.Rfer_4042	1.1e-12	68.2	COG1950@1|root,COG1950@2|Bacteria,1N1DF@1224|Proteobacteria,2VUY1@28216|Betaproteobacteria,4AEEK@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM Membrane protein of	-	-	-	ko:K08972	-	-	-	-	ko00000	-	-	-	Phage_holin_4_2
k141_5171_1	1137281.D778_02343	9.51e-58	184.0	COG3762@1|root,COG3762@2|Bacteria,4NQIT@976|Bacteroidetes,1I266@117743|Flavobacteriia	976|Bacteroidetes	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	TPM_phosphatase
k141_1465_1	67593.Physo137253	4.74e-26	112.0	COG2801@1|root,2RRWG@2759|Eukaryota,3QH6N@4776|Peronosporales	4776|Peronosporales	L	transposition	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_228_1	1196083.SALWKB12_1449	1.52e-23	95.1	COG0522@1|root,COG0522@2|Bacteria,1MW0U@1224|Proteobacteria,2VGZH@28216|Betaproteobacteria,2KPY9@206351|Neisseriales	206351|Neisseriales	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	-	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
k141_228_2	1298593.TOL_3425	1.43e-37	135.0	COG0202@1|root,COG0202@2|Bacteria,1MU75@1224|Proteobacteria,1RMU3@1236|Gammaproteobacteria,1XH9U@135619|Oceanospirillales	135619|Oceanospirillales	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	-	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
k141_8213_1	1189620.AJXL01000008_gene2281	5.38e-41	155.0	COG0474@1|root,COG0474@2|Bacteria,4NERM@976|Bacteroidetes,1HY67@117743|Flavobacteriia,2NUEZ@237|Flavobacterium	976|Bacteroidetes	P	Cation transport ATPase (P-type)	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
k141_853_1	159749.E7BWI2	5.2e-232	647.0	COG0719@1|root,2QRGW@2759|Eukaryota,2XEEX@2836|Bacillariophyta	2836|Bacillariophyta	O	Uncharacterized protein family (UPF0051)	-	-	-	-	-	-	-	-	-	-	-	-	UPF0051
k141_2085_2	1158614.I592_00158	1.87e-06	53.5	COG1061@1|root,COG3886@1|root,COG1061@2|Bacteria,COG3886@2|Bacteria,1TQ62@1239|Firmicutes,4HAJ1@91061|Bacilli,4B101@81852|Enterococcaceae	91061|Bacilli	L	helicase superfamily c-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF3427,Helicase_C,PLDc_2,ResIII
k141_5779_1	1123376.AUIU01000013_gene1772	0.000191	48.9	COG0840@1|root,COG2972@1|root,COG0840@2|Bacteria,COG2972@2|Bacteria,3J11V@40117|Nitrospirae	40117|Nitrospirae	T	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K02660	ko02020,ko02025,map02020,map02025	-	-	-	ko00000,ko00001,ko02035,ko02044	-	-	-	HAMP,MCPsignal
k141_4556_1	375451.RD1_0104	7.21e-83	250.0	2DB77@1|root,2Z7K3@2|Bacteria,1NHMC@1224|Proteobacteria,2U06K@28211|Alphaproteobacteria,2P2NQ@2433|Roseobacter	28211|Alphaproteobacteria	C	Photosynthetic reaction centre protein	pufL	-	-	ko:K08928	ko02020,map02020	M00597	-	-	ko00000,ko00001,ko00002,ko00194	-	-	-	Photo_RC
k141_6408_1	243090.RB11266	3.11e-42	148.0	COG1409@1|root,COG1409@2|Bacteria	2|Bacteria	S	acid phosphatase activity	cpdA	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Metallophos_2
k141_5780_1	626887.J057_16785	1.44e-21	99.0	COG0457@1|root,COG0457@2|Bacteria,1QX0H@1224|Proteobacteria,1T32E@1236|Gammaproteobacteria,46D4D@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6
k141_3303_1	1342299.Z947_1586	1.38e-112	328.0	COG2801@1|root,COG2801@2|Bacteria,1MVN5@1224|Proteobacteria,2TQK0@28211|Alphaproteobacteria,3ZWSZ@60136|Sulfitobacter	28211|Alphaproteobacteria	L	Integrase core domain	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve,rve_3
k141_9486_1	1249627.D779_3177	5.88e-25	100.0	COG2242@1|root,COG2242@2|Bacteria,1R79F@1224|Proteobacteria,1RY3Z@1236|Gammaproteobacteria,1WX5D@135613|Chromatiales	135613|Chromatiales	H	protein methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
k141_9486_2	110663.KI911558_gene1727	1.75e-14	71.6	COG2954@1|root,COG2954@2|Bacteria,1G5NQ@1117|Cyanobacteria,1H05R@1129|Synechococcus	1117|Cyanobacteria	S	protein conserved in bacteria	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	CYTH
k141_7582_1	1123257.AUFV01000006_gene443	3.11e-11	63.5	COG3178@1|root,COG3178@2|Bacteria,1MXCH@1224|Proteobacteria,1RQ1Q@1236|Gammaproteobacteria,1X4P2@135614|Xanthomonadales	135614|Xanthomonadales	S	Phosphotransferase	-	-	2.7.1.221	ko:K07102	ko00520,ko01100,map00520,map01100	-	R08968,R11024	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	APH
k141_854_1	565045.NOR51B_2490	5.01e-27	112.0	COG0823@1|root,COG0823@2|Bacteria,1MV09@1224|Proteobacteria,1RMCY@1236|Gammaproteobacteria,1J4F8@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	U	Involved in the TonB-independent uptake of proteins	tolB	GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006810,GO:0008104,GO:0008150,GO:0009719,GO:0009987,GO:0010033,GO:0010243,GO:0015031,GO:0015833,GO:0015893,GO:0017038,GO:0019904,GO:0030288,GO:0030313,GO:0031975,GO:0032153,GO:0032991,GO:0033036,GO:0042221,GO:0042493,GO:0042597,GO:0042886,GO:0042891,GO:0043213,GO:0044464,GO:0044877,GO:0045184,GO:0046677,GO:0046678,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0070887,GO:0071236,GO:0071237,GO:0071310,GO:0071417,GO:0071495,GO:0071702,GO:0071705,GO:1901652,GO:1901653,GO:1901698,GO:1901699,GO:1901700,GO:1901701	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40,TolB_N
k141_854_2	1123256.KB907932_gene2931	3.15e-08	57.4	COG3064@1|root,COG3064@2|Bacteria,1NDEI@1224|Proteobacteria,1T2B3@1236|Gammaproteobacteria,1X89R@135614|Xanthomonadales	135614|Xanthomonadales	M	TonB C terminal	-	-	-	-	-	-	-	-	-	-	-	-	TonB_2
k141_5172_3	136037.KDR07346	2.93e-54	180.0	COG0852@1|root,KOG1713@2759|Eukaryota,38BAK@33154|Opisthokonta,3B9TX@33208|Metazoa,3CTAV@33213|Bilateria,41TR8@6656|Arthropoda,3SHA9@50557|Insecta	33208|Metazoa	C	Belongs to the complex I 30 kDa subunit family	NDUFS3	GO:0001558,GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005746,GO:0005747,GO:0005759,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006996,GO:0007005,GO:0008137,GO:0008150,GO:0008152,GO:0009055,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009966,GO:0009968,GO:0009987,GO:0010257,GO:0010646,GO:0010648,GO:0010941,GO:0015980,GO:0016020,GO:0016043,GO:0016310,GO:0016491,GO:0016604,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0019866,GO:0022607,GO:0022900,GO:0022904,GO:0023051,GO:0023057,GO:0030308,GO:0030964,GO:0031090,GO:0031966,GO:0031967,GO:0031974,GO:0031975,GO:0031981,GO:0032981,GO:0032991,GO:0033108,GO:0034622,GO:0034641,GO:0040008,GO:0042773,GO:0042775,GO:0042981,GO:0043066,GO:0043067,GO:0043069,GO:0043209,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044281,GO:0044422,GO:0044424,GO:0044425,GO:0044428,GO:0044429,GO:0044444,GO:0044446,GO:0044451,GO:0044455,GO:0044464,GO:0045271,GO:0045333,GO:0045926,GO:0046034,GO:0046483,GO:0048519,GO:0048523,GO:0048583,GO:0048585,GO:0050136,GO:0050789,GO:0050794,GO:0051128,GO:0055086,GO:0055114,GO:0060548,GO:0065003,GO:0065007,GO:0070013,GO:0070469,GO:0071704,GO:0071840,GO:0072521,GO:0072593,GO:0098796,GO:0098798,GO:0098800,GO:0098803,GO:1901135,GO:1901360,GO:1901564,GO:1902494,GO:1902531,GO:1902532,GO:1990204,GO:2001233,GO:2001234,GO:2001242,GO:2001243	1.6.5.3,1.6.99.3	ko:K03936	ko00190,ko01100,ko04714,ko04723,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map04714,map04723,map04932,map05010,map05012,map05016	M00143	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1.6	-	-	Complex1_30kDa
k141_3928_1	1173020.Cha6605_3178	1.14e-68	215.0	COG0522@1|root,COG0522@2|Bacteria,1G03U@1117|Cyanobacteria	1117|Cyanobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rps4	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
k141_3304_1	911045.PSE_4812	2.29e-75	237.0	COG4663@1|root,COG4663@2|Bacteria,1MVMD@1224|Proteobacteria,2TS4J@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	Part of the tripartite ATP-independent periplasmic (TRAP) transport system	-	-	-	-	-	-	-	-	-	-	-	-	DctP
k141_7163_1	999549.KI421513_gene3233	2.32e-65	211.0	COG0150@1|root,COG0150@2|Bacteria,1MURG@1224|Proteobacteria,2TR6G@28211|Alphaproteobacteria,2818C@191028|Leisingera	28211|Alphaproteobacteria	F	AIR synthase related protein, C-terminal domain	purM	-	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
k141_4083_1	1342299.Z947_3119	1.82e-10	59.7	COG4105@1|root,COG4105@2|Bacteria,1MVS5@1224|Proteobacteria,2TRZ5@28211|Alphaproteobacteria,3ZUWT@60136|Sulfitobacter	28211|Alphaproteobacteria	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamD	-	-	ko:K05807	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	YfiO
k141_4083_2	391624.OIHEL45_11163	4.47e-74	240.0	COG0497@1|root,COG0497@2|Bacteria,1MUNP@1224|Proteobacteria,2TREW@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	May be involved in recombinational repair of damaged DNA	recN	-	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	SMC_N
k141_8959_1	2340.JV46_05690	1.43e-133	387.0	COG2826@1|root,COG2826@2|Bacteria,1PP49@1224|Proteobacteria,1RN7B@1236|Gammaproteobacteria,1JBRQ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	L	L COG2826 Transposase and inactivated derivatives, IS30 family	insI	GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0004803,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006310,GO:0006313,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0030983,GO:0032135,GO:0032196,GO:0032991,GO:0032993,GO:0034641,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363	-	ko:K07482	-	-	-	-	ko00000	-	-	-	HTH_38,rve
k141_995_1	857087.Metme_0981	5.41e-87	263.0	COG0708@1|root,COG0708@2|Bacteria,1MVII@1224|Proteobacteria,1RN4H@1236|Gammaproteobacteria,1XEVR@135618|Methylococcales	135618|Methylococcales	L	Endonuclease/Exonuclease/phosphatase family	-	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
k141_5929_1	7176.CPIJ004938-PA	3.93e-10	64.7	COG3119@1|root,KOG3731@2759|Eukaryota,39MZA@33154|Opisthokonta,3CPIJ@33208|Metazoa,3E5PF@33213|Bilateria,41VPH@6656|Arthropoda,3SH99@50557|Insecta,44Z14@7147|Diptera,45F6G@7148|Nematocera	33208|Metazoa	G	Iduronate 2-sulfatase	-	-	3.1.6.13	ko:K01136	ko00531,ko01100,ko04142,map00531,map01100,map04142	M00076,M00078	R07812,R07821	-	ko00000,ko00001,ko00002,ko01000	-	-	-	Sulfatase
k141_3446_1	351016.RAZWK3B_20086	9.99e-19	84.7	COG4372@1|root,COG4372@2|Bacteria,1MUCX@1224|Proteobacteria,2TR59@28211|Alphaproteobacteria,2P2RV@2433|Roseobacter	28211|Alphaproteobacteria	S	COG3436 Transposase and inactivated derivatives	-	-	-	ko:K07484	-	-	-	-	ko00000	-	-	-	DDE_Tnp_IS66,DDE_Tnp_IS66_C,LZ_Tnp_IS66,zf-IS66
k141_3446_2	351016.RAZWK3B_20096	2.41e-67	205.0	COG3436@1|root,COG3436@2|Bacteria,1MZFT@1224|Proteobacteria,2U7MB@28211|Alphaproteobacteria,2P3P7@2433|Roseobacter	28211|Alphaproteobacteria	L	COG3436 Transposase and inactivated derivatives	-	-	-	ko:K07484	-	-	-	-	ko00000	-	-	-	TnpB_IS66
k141_385_1	436308.Nmar_1585	3.05e-109	323.0	COG0079@1|root,arCOG04273@2157|Archaea,41SGU@651137|Thaumarchaeota	651137|Thaumarchaeota	E	PFAM Aminotransferase class I and II	-	-	4.1.1.81	ko:K04720	ko00860,map00860	-	R06530	RC00517	ko00000,ko00001,ko01000	-	-	-	Aminotran_1_2
k141_2241_1	1249997.JHZW01000001_gene4157	2.44e-118	347.0	COG0343@1|root,COG0343@2|Bacteria,4NE15@976|Bacteroidetes,1HXAZ@117743|Flavobacteriia,2PGE8@252356|Maribacter	976|Bacteroidetes	J	Queuine tRNA-ribosyltransferase	tgt	-	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
k141_386_1	583355.Caka_1187	4.31e-70	222.0	COG2114@1|root,COG2114@2|Bacteria	2|Bacteria	T	Pfam Adenylate and Guanylate cyclase catalytic domain	-	-	3.1.3.3,4.6.1.1	ko:K01768,ko:K07315	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000,ko03021	-	-	-	Guanylate_cyc,HAMP,Response_reg,dCache_1
k141_4086_1	1205680.CAKO01000038_gene1921	4.95e-97	288.0	COG0479@1|root,COG0479@2|Bacteria,1MVHS@1224|Proteobacteria,2TQYF@28211|Alphaproteobacteria,2JPYJ@204441|Rhodospirillales	204441|Rhodospirillales	C	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family	sdhB	-	1.3.5.1,1.3.5.4	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_3,Fer4_17,Fer4_8
k141_7166_2	857087.Metme_4542	2.46e-122	356.0	COG0752@1|root,COG0752@2|Bacteria,1MVCJ@1224|Proteobacteria,1RMYI@1236|Gammaproteobacteria,1XDMU@135618|Methylococcales	135618|Methylococcales	J	glycyl-tRNA synthetase	glyQ	-	6.1.1.14	ko:K01878	ko00970,map00970	M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2e
k141_7732_1	1128421.JAGA01000003_gene3726	5.33e-07	50.4	COG1012@1|root,COG1012@2|Bacteria,2NNWB@2323|unclassified Bacteria	2|Bacteria	C	Belongs to the aldehyde dehydrogenase family	aldA	-	1.2.1.3,1.2.1.8	ko:K00128,ko:K00130,ko:K00138	ko00010,ko00053,ko00071,ko00260,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00260,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135,M00555	R00264,R00631,R00710,R00711,R00904,R01752,R01986,R02549,R02565,R02566,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
k141_7732_2	666509.RCA23_c01320	1.22e-80	248.0	COG0274@1|root,COG0274@2|Bacteria,1N8AG@1224|Proteobacteria,2TS26@28211|Alphaproteobacteria	28211|Alphaproteobacteria	F	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate	deoC	-	4.1.2.4	ko:K01619	ko00030,map00030	-	R01066	RC00436,RC00437	ko00000,ko00001,ko01000	-	-	-	DeoC
k141_5932_1	1232683.ADIMK_0341	8.31e-58	191.0	COG0707@1|root,COG0707@2|Bacteria,1MVIB@1224|Proteobacteria,1RMQ3@1236|Gammaproteobacteria,464K0@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008194,GO:0008375,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0050511,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	iSFV_1184.SFV_0083,iSF_1195.SF0087,iSFxv_1172.SFxv_0091,iS_1188.S0089	Glyco_tran_28_C,Glyco_transf_28
k141_3448_1	2850.Phatr18826	8.99e-32	127.0	COG1132@1|root,KOG0054@2759|Eukaryota,2XBJJ@2836|Bacillariophyta	2836|Bacillariophyta	Q	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_membrane,ABC_tran
k141_3448_2	2850.Phatr18826	2.03e-17	80.9	COG1132@1|root,KOG0054@2759|Eukaryota,2XBJJ@2836|Bacillariophyta	2836|Bacillariophyta	Q	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_membrane,ABC_tran
k141_5325_1	999550.KI421507_gene1945	1.19e-104	314.0	COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,2TRPK@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Aminotransferase	aatA	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
k141_4707_1	1116375.VEJY3_01090	1.8e-75	239.0	COG0677@1|root,COG0677@2|Bacteria,1MUC6@1224|Proteobacteria,1RMX0@1236|Gammaproteobacteria,1XSY5@135623|Vibrionales	135623|Vibrionales	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	-	-	-	ko:K02474	ko00520,map00520	-	R06894	RC00291	ko00000,ko00001,ko01000,ko01005	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
k141_8367_1	1158165.KB898872_gene1156	4.06e-06	49.7	COG2010@1|root,COG2010@2|Bacteria,1NE41@1224|Proteobacteria,1SFE5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
k141_3449_1	111781.Lepto7376_2297	2.09e-69	225.0	COG0069@1|root,COG2146@1|root,COG0069@2|Bacteria,COG2146@2|Bacteria,1G0XM@1117|Cyanobacteria,1H8GB@1150|Oscillatoriales	1117|Cyanobacteria	E	PFAM Conserved region in glutamate synthase	-	-	-	-	-	-	-	-	-	-	-	-	Glu_synthase
k141_2243_1	981223.AIED01000057_gene2655	1.14e-35	135.0	COG0399@1|root,COG0399@2|Bacteria,1MUMJ@1224|Proteobacteria,1RSDY@1236|Gammaproteobacteria,3NKKZ@468|Moraxellaceae	1236|Gammaproteobacteria	M	Putative transposase	-	-	-	-	-	-	-	-	-	-	-	-	Y2_Tnp,Zn_Tnp_IS91
k141_2243_2	1127673.GLIP_0766	1.05e-05	47.8	COG0399@1|root,COG0399@2|Bacteria,1MUMJ@1224|Proteobacteria,1RSDY@1236|Gammaproteobacteria,469FZ@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	Transposase zinc-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Y2_Tnp,Zn_Tnp_IS91
k141_5326_1	1085623.GNIT_2957	1.14e-30	119.0	COG0845@1|root,COG0845@2|Bacteria,1PDUT@1224|Proteobacteria,1RQKD@1236|Gammaproteobacteria,4665P@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	HlyD family secretion protein	-	-	-	ko:K02005,ko:K13888	-	M00709	-	-	ko00000,ko00002,ko02000	8.A.1	-	-	HlyD_3,HlyD_D23,OEP
k141_5326_2	411684.HPDFL43_03701	4.25e-14	72.4	COG0577@1|root,COG0577@2|Bacteria,1MW6D@1224|Proteobacteria,2TTJZ@28211|Alphaproteobacteria,43JFR@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	V	COG0577 ABC-type antimicrobial peptide transport system, permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
k141_4708_1	1120949.KB903294_gene3562	3.29e-52	175.0	COG3959@1|root,COG3959@2|Bacteria,2GJ6M@201174|Actinobacteria,4DDKR@85008|Micromonosporales	201174|Actinobacteria	G	Transketolase, thiamine diphosphate binding domain	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
k141_8368_1	159749.E7BWF3	1.93e-17	84.0	2CACG@1|root,2RWZ1@2759|Eukaryota,2XE6M@2836|Bacillariophyta	2836|Bacillariophyta	S	Uncharacterised protein family	ycf90	-	-	-	-	-	-	-	-	-	-	-	YCF90
k141_1622_1	203275.BFO_0497	1.16e-42	158.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,4NFBK@976|Bacteroidetes,2FM6S@200643|Bacteroidia	976|Bacteroidetes	E	Dienelactone hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S9
k141_7734_1	391595.RLO149_c016090	3.19e-61	196.0	COG1741@1|root,COG1741@2|Bacteria,1MWIP@1224|Proteobacteria,2TRHR@28211|Alphaproteobacteria,2P1GM@2433|Roseobacter	28211|Alphaproteobacteria	S	Pirin	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin,Pirin_C
k141_6026_1	997350.HMPREF9129_1230	4.52e-30	122.0	COG0515@1|root,COG0515@2|Bacteria,1TP3F@1239|Firmicutes,2492G@186801|Clostridia,22GF2@1570339|Peptoniphilaceae	186801|Clostridia	KLT	Kinase domain protein	prkC	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
k141_6652_1	1123355.JHYO01000007_gene445	5.89e-07	51.6	COG1664@1|root,COG1664@2|Bacteria,1MZN0@1224|Proteobacteria,2U5DW@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	Integral membrane protein CcmA involved in cell shape determination	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
k141_6652_2	1380391.JIAS01000020_gene1461	3.95e-31	121.0	COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,2TQZE@28211|Alphaproteobacteria,2JRC1@204441|Rhodospirillales	204441|Rhodospirillales	M	Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
k141_1101_1	436308.Nmar_0354	5.71e-14	67.4	COG0048@1|root,arCOG04255@2157|Archaea,41SIB@651137|Thaumarchaeota	651137|Thaumarchaeota	J	With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits	rps12	-	-	ko:K02950	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosom_S12_S23
k141_1101_2	436308.Nmar_0353	2.21e-86	255.0	COG0195@1|root,arCOG01760@2157|Archaea,41SJQ@651137|Thaumarchaeota	651137|Thaumarchaeota	K	Participates in transcription termination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KH_2
k141_4195_1	631362.Thi970DRAFT_00496	3.97e-59	197.0	28K6U@1|root,2Z9V7@2|Bacteria,1MYVN@1224|Proteobacteria,1S0GU@1236|Gammaproteobacteria,1WW9K@135613|Chromatiales	135613|Chromatiales	S	TIGRFAM carboxysome shell carbonic anhydrase	-	-	-	-	-	-	-	-	-	-	-	-	CsoSCA
k141_7828_1	1121875.KB907549_gene2005	1.08e-149	446.0	COG1882@1|root,COG1882@2|Bacteria,4NDWW@976|Bacteroidetes,1I0UR@117743|Flavobacteriia	976|Bacteroidetes	C	Pyruvate formate lyase-like	-	-	2.3.1.54,4.1.1.83	ko:K00656,ko:K18427	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	-	R00212,R06987	RC00004,RC01181,RC02742,RC02833	ko00000,ko00001,ko01000	-	-	-	Gly_radical,PFL-like
k141_9715_1	450851.PHZ_c2212	3.33e-48	169.0	COG5323@1|root,COG5323@2|Bacteria,1R0EP@1224|Proteobacteria,2TYQ7@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Terminase RNaseH-like domain	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_8471_1	1279019.ARQK01000060_gene2216	1.77e-63	206.0	COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,1RMCS@1236|Gammaproteobacteria,1WWP0@135613|Chromatiales	135613|Chromatiales	E	Belongs to the DegT DnrJ EryC1 family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
k141_3535_1	7668.SPU_014898-tr	1.28e-81	258.0	KOG1075@1|root,KOG1075@2759|Eukaryota,3A35Z@33154|Opisthokonta,3BQYF@33208|Metazoa,3D7GC@33213|Bilateria	33208|Metazoa	S	Ribonuclease H protein	-	-	-	-	-	-	-	-	-	-	-	-	RVT_1
k141_5424_1	1121871.AUAT01000011_gene504	7.52e-37	133.0	COG0605@1|root,COG0605@2|Bacteria,1TPXT@1239|Firmicutes,4HA6U@91061|Bacilli,27DUT@186827|Aerococcaceae	91061|Bacilli	P	Destroys radicals which are normally produced within the cells and which are toxic to biological systems	sodA	GO:0005575,GO:0005576	1.15.1.1	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Fe_C,Sod_Fe_N
k141_6653_2	202698.XP_007389360.1	1.01e-15	75.5	KOG4853@1|root,KOG4853@2759|Eukaryota,3AB25@33154|Opisthokonta,3P6T1@4751|Fungi,3V6Q2@5204|Basidiomycota,22CXY@155619|Agaricomycetes	4751|Fungi	S	encoded within the 25S rRNA gene on the opposite strand	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0008150,GO:0019222,GO:0031323,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043457,GO:0043467,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0065007	-	-	-	-	-	-	-	-	-	-	-
k141_9716_1	1415778.JQMM01000001_gene29	1.24e-50	172.0	COG0809@1|root,COG0809@2|Bacteria,1MUH3@1224|Proteobacteria,1RMKW@1236|Gammaproteobacteria,1J4SK@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	queA	GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009314,GO:0009451,GO:0009628,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046116,GO:0046483,GO:0050896,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
k141_2340_1	1041146.ATZB01000008_gene2192	4.28e-57	198.0	28HMZ@1|root,2Z7WD@2|Bacteria,1MU3Q@1224|Proteobacteria,2TSGX@28211|Alphaproteobacteria,4BCDP@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Protein of unknown function (DUF3604)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3604
k141_7262_1	998674.ATTE01000001_gene2262	7.45e-55	187.0	COG0750@1|root,COG0750@2|Bacteria,1MU91@1224|Proteobacteria,1RMIX@1236|Gammaproteobacteria,460AB@72273|Thiotrichales	72273|Thiotrichales	M	zinc metalloprotease	-	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_M50
k141_6029_1	595537.Varpa_4424	1.39e-71	226.0	COG2230@1|root,COG2230@2|Bacteria,1MUW5@1224|Proteobacteria,2VI5F@28216|Betaproteobacteria,4ACT9@80864|Comamonadaceae	28216|Betaproteobacteria	M	Mycolic acid cyclopropane synthetase	-	-	2.1.1.79	ko:K00574	-	-	-	-	ko00000,ko01000	-	-	-	CMAS
k141_9061_1	1049564.TevJSym_aj00080	2.63e-21	91.7	COG3637@1|root,COG3637@2|Bacteria,1RDPZ@1224|Proteobacteria,1S4GQ@1236|Gammaproteobacteria,1JADW@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl
k141_9061_2	1121935.AQXX01000098_gene1656	1.44e-13	69.3	COG3807@1|root,COG3807@2|Bacteria,1RE8W@1224|Proteobacteria,1S4BU@1236|Gammaproteobacteria,1XPIQ@135619|Oceanospirillales	135619|Oceanospirillales	S	COG3103 SH3 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl,SH3_3,SH3_4
k141_8472_1	1026882.MAMP_01952	6.5e-53	191.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,460B2@72273|Thiotrichales	72273|Thiotrichales	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
k141_1726_1	35128.Thapsdraft989	2.56e-31	112.0	COG0268@1|root,2R9BJ@2759|Eukaryota,2XH98@2836|Bacillariophyta	2836|Bacillariophyta	J	Binds directly to 16S ribosomal RNA	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009536,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464	-	-	-	-	-	-	-	-	-	-	Ribosomal_S20p
k141_7263_2	754476.Q7A_1272	8.97e-42	142.0	COG0669@1|root,COG0669@2|Bacteria,1RD9F@1224|Proteobacteria,1S41J@1236|Gammaproteobacteria,460XS@72273|Thiotrichales	72273|Thiotrichales	H	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	-	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
k141_6030_1	384765.SIAM614_02611	4.34e-17	80.1	COG1228@1|root,COG1228@2|Bacteria,1MVAF@1224|Proteobacteria,2TTYC@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	COG1228 Imidazolonepropionase and related amidohydrolases	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
k141_5426_1	351016.RAZWK3B_10306	2.7e-41	145.0	COG0739@1|root,COG0739@2|Bacteria,1PVZJ@1224|Proteobacteria,2TRAB@28211|Alphaproteobacteria,2P1NV@2433|Roseobacter	28211|Alphaproteobacteria	M	COG0739 Membrane proteins related to metalloendopeptidases	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
k141_5426_2	1354722.JQLS01000008_gene2502	2.58e-19	86.7	COG0542@1|root,COG0542@2|Bacteria,1MV8B@1224|Proteobacteria,2TQUZ@28211|Alphaproteobacteria,46NEK@74030|Roseovarius	28211|Alphaproteobacteria	O	ATP-dependent Clp protease ATP-binding subunit ClpA	clpA	GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0043335,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564	-	ko:K03694	-	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
k141_490_1	1229909.NSED_09330	1.42e-77	236.0	COG1010@1|root,arCOG00647@2157|Archaea,41S6W@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Tetrapyrrole (Corrin/Porphyrin) Methylases	-	-	2.1.1.131	ko:K05934	ko00860,ko01100,map00860,map01100	-	R05180,R05809	RC00003,RC01293,RC03471	ko00000,ko00001,ko01000	-	-	-	TP_methylase
k141_490_2	1229909.NSED_09335	4.07e-09	56.2	arCOG08764@1|root,arCOG08764@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_9062_1	436308.Nmar_0224	1.76e-32	122.0	COG1109@1|root,arCOG00767@2157|Archaea,41S74@651137|Thaumarchaeota	651137|Thaumarchaeota	G	Belongs to the phosphohexose mutase family	-	-	5.4.2.2,5.4.2.8	ko:K15778	ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00114	R00959,R01057,R01818,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
k141_9062_2	1229909.NSED_00940	1e-21	90.9	COG0788@1|root,arCOG02826@2157|Archaea,41S78@651137|Thaumarchaeota	651137|Thaumarchaeota	F	Formyl transferase	-	-	3.5.1.10	ko:K01433	ko00630,ko00670,map00630,map00670	-	R00944	RC00026,RC00111	ko00000,ko00001,ko01000	-	-	-	ACT_6,Formyl_trans_N
k141_7264_1	396588.Tgr7_2330	1.23e-87	288.0	COG0086@1|root,COG0086@2|Bacteria,1MU3M@1224|Proteobacteria,1RPYH@1236|Gammaproteobacteria,1WVVI@135613|Chromatiales	135613|Chromatiales	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	-	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
k141_7832_1	1121378.KB899697_gene2908	4.1e-30	120.0	COG0534@1|root,COG0534@2|Bacteria	2|Bacteria	V	drug transmembrane transporter activity	norM	-	-	ko:K03327	-	-	-	-	ko00000,ko02000	2.A.66.1	-	-	MatE
k141_9063_1	870187.Thini_2948	1.63e-92	291.0	COG2225@1|root,COG2225@2|Bacteria,1MVEV@1224|Proteobacteria,1RPVI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA	glcB	GO:0000287,GO:0003674,GO:0003824,GO:0004474,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009436,GO:0009987,GO:0016054,GO:0016740,GO:0016746,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046185,GO:0046395,GO:0046487,GO:0046872,GO:0046912,GO:0071704,GO:0072329,GO:1901575	2.3.3.9	ko:K01638	ko00620,ko00630,ko01100,ko01110,ko01120,ko01200,map00620,map00630,map01100,map01110,map01120,map01200	M00012	R00472	RC00004,RC00308,RC02747	ko00000,ko00001,ko00002,ko01000	-	-	iECSF_1327.ECSF_2799,iECW_1372.ECW_m3242,iEKO11_1354.EKO11_0745,iWFL_1372.ECW_m3242	Malate_synthase
k141_9673_1	388401.RB2150_12331	1.45e-35	127.0	COG2227@1|root,COG2227@2|Bacteria,1MU89@1224|Proteobacteria,2TRIK@28211|Alphaproteobacteria,3ZGMP@58840|unclassified Rhodobacteraceae	28211|Alphaproteobacteria	H	O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway	ubiG	-	2.1.1.222,2.1.1.64	ko:K00568	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04988,R05614,R08769,R08781	RC00003,RC00392,RC01895	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11,Methyltransf_23
k141_9673_2	1123360.thalar_03374	5.84e-34	125.0	COG0596@1|root,COG0596@2|Bacteria,1MWW8@1224|Proteobacteria,2TS53@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Belongs to the peptidase S33 family	pip	-	3.4.11.5	ko:K01259	ko00330,map00330	-	R00135	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Abhydrolase_1
k141_7224_1	1380391.JIAS01000006_gene2502	2.61e-39	145.0	COG0472@1|root,COG0472@2|Bacteria,1MUTK@1224|Proteobacteria,2TRUG@28211|Alphaproteobacteria,2JQ3T@204441|Rhodospirillales	204441|Rhodospirillales	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	-	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	-	Glycos_transf_4,MraY_sig1
k141_4764_1	1353537.TP2_00220	1.3e-07	53.5	COG0374@1|root,COG0374@2|Bacteria,1MWFJ@1224|Proteobacteria,2TSH1@28211|Alphaproteobacteria,2XP7H@285107|Thioclava	28211|Alphaproteobacteria	C	Belongs to the NiFe NiFeSe hydrogenase large subunit family	hupL	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	1.12.99.6	ko:K06281	ko00633,ko01120,map00633,map01120	-	R08034	RC00250	ko00000,ko00001,ko01000	-	-	-	NiFeSe_Hases
k141_2298_1	391615.ABSJ01000046_gene2114	2.24e-50	172.0	COG1638@1|root,COG1638@2|Bacteria	2|Bacteria	G	carbohydrate transport	-	-	-	ko:K11688,ko:K21395	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.56.1	-	-	DctP
k141_9015_1	2340.JV46_07630	1.11e-130	382.0	COG1850@1|root,COG1850@2|Bacteria,1MWEB@1224|Proteobacteria,1RRMX@1236|Gammaproteobacteria,1J7UP@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	G	Ribulose bisphosphate carboxylase large chain, catalytic domain	cbbL	-	4.1.1.39	ko:K01601	ko00630,ko00710,ko01100,ko01120,ko01200,map00630,map00710,map01100,map01120,map01200	M00165,M00166,M00532	R00024,R03140	RC00172,RC00859	ko00000,ko00001,ko00002,ko01000	-	-	-	RuBisCO_large,RuBisCO_large_N
k141_9674_1	1229909.NSED_00850	9.33e-85	254.0	arCOG08023@1|root,arCOG08023@2157|Archaea,41SKK@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Zinc finger domain	-	-	-	-	-	-	-	-	-	-	-	-	zinc_ribbon_2
k141_8426_1	497964.CfE428DRAFT_4431	0.000421	48.5	COG1361@1|root,COG1520@1|root,COG1572@1|root,COG3227@1|root,COG1361@2|Bacteria,COG1520@2|Bacteria,COG1572@2|Bacteria,COG3227@2|Bacteria	2|Bacteria	E	Zinc metalloprotease (Elastase)	-	-	-	ko:K20274	ko02024,map02024	-	-	-	ko00000,ko00001,ko01002	-	-	-	CHU_C,FTP,PQQ_2,Peptidase_M36
k141_4765_1	935848.JAEN01000016_gene2341	5.77e-80	250.0	COG1282@1|root,COG1282@2|Bacteria,1MUP4@1224|Proteobacteria,2TQN1@28211|Alphaproteobacteria,2PUDE@265|Paracoccus	28211|Alphaproteobacteria	C	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane	pntB	-	1.6.1.2	ko:K00325	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	PNTB
k141_5384_1	1134474.O59_003688	1.21e-70	220.0	COG0321@1|root,COG0321@2|Bacteria,1MU6A@1224|Proteobacteria,1RMXQ@1236|Gammaproteobacteria,1FGMW@10|Cellvibrio	1236|Gammaproteobacteria	H	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate	lipB	GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016053,GO:0016415,GO:0016740,GO:0016746,GO:0016747,GO:0016772,GO:0016779,GO:0016874,GO:0016879,GO:0016979,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019222,GO:0019538,GO:0019752,GO:0032787,GO:0033819,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048519,GO:0050789,GO:0051186,GO:0051188,GO:0051604,GO:0060255,GO:0065007,GO:0071704,GO:0072330,GO:0140096,GO:1901360,GO:1901362,GO:1901564,GO:1901576	2.3.1.181	ko:K03801	ko00785,ko01100,map00785,map01100	-	R07766,R07769	RC00039,RC00992,RC02867	ko00000,ko00001,ko01000	-	-	iECSF_1327.ECSF_0569,iSFV_1184.SFV_0696,iSFxv_1172.SFxv_0718	BPL_LplA_LipB
k141_6613_1	314345.SPV1_01822	1.44e-78	239.0	COG2020@1|root,COG2020@2|Bacteria,1R7G6@1224|Proteobacteria	1224|Proteobacteria	O	Methyl-transferase	-	-	-	-	-	-	-	-	-	-	-	-	ICMT,PEMT
k141_5982_2	398578.Daci_0333	5.73e-25	103.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,2VHQD@28216|Betaproteobacteria,4AAXG@80864|Comamonadaceae	28216|Betaproteobacteria	C	PFAM Aldehyde dehydrogenase	-	-	1.2.1.3,1.2.1.8	ko:K00128,ko:K00130	ko00010,ko00053,ko00071,ko00260,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00260,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135,M00555	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02565,R02566,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
k141_4147_1	1229909.NSED_01330	2.05e-39	142.0	COG1007@1|root,arCOG01540@2157|Archaea,41SDU@651137|Thaumarchaeota	651137|Thaumarchaeota	C	NADH ubiquinone oxidoreductase subunit 2 (Chain N)	-	-	1.5.98.3	ko:K22169	-	-	-	-	ko00000,ko01000	3.D.9.1	-	-	Proton_antipo_M
k141_4147_2	1229909.NSED_01325	1.34e-56	192.0	COG1009@1|root,arCOG01539@2157|Archaea,41SC4@651137|Thaumarchaeota	651137|Thaumarchaeota	C	TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain L	-	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M,Proton_antipo_N
k141_1684_1	159749.E7BWC8	1.65e-73	226.0	COG0081@1|root,KOG1569@2759|Eukaryota,2XFIB@2836|Bacillariophyta	2836|Bacillariophyta	J	Binds directly to 23S rRNA. Might be involved in E site tRNA release	-	GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009507,GO:0009536,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	-	-	-	-	-	-	-	-	-	Ribosomal_L1
k141_6614_1	713586.KB900536_gene91	1.71e-76	247.0	COG0493@1|root,COG1143@1|root,COG0493@2|Bacteria,COG1143@2|Bacteria,1MU2H@1224|Proteobacteria,1RREP@1236|Gammaproteobacteria,1WWDT@135613|Chromatiales	135613|Chromatiales	C	PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_20,Fer4_7,Pyr_redox_2
k141_9017_1	83406.HDN1F_19210	5.2e-43	150.0	COG0218@1|root,COG0218@2|Bacteria,1MY3Z@1224|Proteobacteria,1RNJP@1236|Gammaproteobacteria,1JA7U@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	D	Necessary for normal cell division and for the maintenance of normal septation	engB	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0017076,GO:0019001,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	ko:K03978	-	-	-	-	ko00000,ko03036	-	-	-	MMR_HSR1
k141_449_1	998088.B565_1514	1.2e-24	100.0	COG4215@1|root,COG4215@2|Bacteria,1MY2N@1224|Proteobacteria,1RNYD@1236|Gammaproteobacteria,1Y47J@135624|Aeromonadales	135624|Aeromonadales	P	ABC transporter	-	-	-	ko:K10024	ko02010,map02010	M00235	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3.11	-	-	BPD_transp_1
k141_449_2	287.DR97_5018	5.03e-10	60.5	COG0834@1|root,COG0834@2|Bacteria,1NT2J@1224|Proteobacteria,1S077@1236|Gammaproteobacteria,1YEK3@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	ET	Ligated ion channel L-glutamate- and glycine-binding site	aotJ	-	-	ko:K09997,ko:K10014,ko:K10022	ko02010,map02010	M00226,M00229,M00235	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3.1,3.A.1.3.11,3.A.1.3.3	-	-	SBP_bac_3
k141_8429_1	89187.ISM_05100	5.54e-51	172.0	COG2177@1|root,COG2177@2|Bacteria,1MXKQ@1224|Proteobacteria,2TSNT@28211|Alphaproteobacteria,46NCZ@74030|Roseovarius	28211|Alphaproteobacteria	D	COG2177 Cell division protein	ftsX	-	-	ko:K09811	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	-
k141_1061_1	348824.LPU83_pLPU83a_0068	3.26e-103	301.0	COG3335@1|root,COG3335@2|Bacteria,1RB1C@1224|Proteobacteria,2U367@28211|Alphaproteobacteria,4BC4T@82115|Rhizobiaceae	28211|Alphaproteobacteria	L	protein y4pE y4sA	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3
k141_9018_1	90813.JQMT01000001_gene1784	5.56e-10	57.0	COG3536@1|root,COG3536@2|Bacteria,1MZ5M@1224|Proteobacteria,1S8TB@1236|Gammaproteobacteria,460YN@72273|Thiotrichales	72273|Thiotrichales	S	Protein of unknown function (DUF971)	-	-	-	-	-	-	-	-	-	-	-	-	DUF971
k141_9018_2	1027273.GZ77_12555	9.04e-56	181.0	COG0500@1|root,COG2226@2|Bacteria,1MX8I@1224|Proteobacteria,1RMAU@1236|Gammaproteobacteria,1XI77@135619|Oceanospirillales	135619|Oceanospirillales	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2)	ubiE	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
k141_4150_1	1049564.TevJSym_au00010	1.27e-33	133.0	COG4105@1|root,COG4105@2|Bacteria,1QVQ9@1224|Proteobacteria,1RSIG@1236|Gammaproteobacteria,1J8QI@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6
k141_5985_1	546274.EIKCOROL_01699	2.99e-55	176.0	COG0522@1|root,COG0522@2|Bacteria,1MW0U@1224|Proteobacteria,2VGZH@28216|Betaproteobacteria,2KPY9@206351|Neisseriales	206351|Neisseriales	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	-	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
k141_5985_2	1479235.KK366039_gene2492	6.19e-21	90.5	COG0202@1|root,COG0202@2|Bacteria,1MU75@1224|Proteobacteria,1RMU3@1236|Gammaproteobacteria,1XH9U@135619|Oceanospirillales	135619|Oceanospirillales	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	-	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
k141_3494_1	1255043.TVNIR_0911	5.89e-29	119.0	COG4584@1|root,COG4584@2|Bacteria,1MU2G@1224|Proteobacteria,1RQA2@1236|Gammaproteobacteria,1WYPQ@135613|Chromatiales	135613|Chromatiales	L	PFAM Integrase catalytic	-	-	-	-	-	-	-	-	-	-	-	-	rve
k141_7793_1	551275.KB899544_gene916	3.62e-69	231.0	COG1033@1|root,COG1033@2|Bacteria,1MUE1@1224|Proteobacteria,2TWVC@28211|Alphaproteobacteria,440R8@69657|Hyphomonadaceae	28211|Alphaproteobacteria	S	Sterol-sensing domain of SREBP cleavage-activation	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
k141_8431_1	247634.GPB2148_1008	2.1e-60	197.0	COG0505@1|root,COG0505@2|Bacteria,1MUB9@1224|Proteobacteria,1RMAW@1236|Gammaproteobacteria,1J4TG@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	F	Belongs to the CarA family	carA	GO:0000050,GO:0003674,GO:0003824,GO:0004088,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005951,GO:0006082,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006520,GO:0006525,GO:0006526,GO:0006541,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019627,GO:0019637,GO:0019693,GO:0019752,GO:0019856,GO:0032991,GO:0034641,GO:0034654,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046394,GO:0046483,GO:0055086,GO:0071704,GO:0071941,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	iAPECO1_1312.APECO1_1950,iUTI89_1310.UTI89_C0036,ic_1306.c0040	CPSase_sm_chain,GATase
k141_1686_1	7213.XP_004527970.1	2.1e-15	77.4	COG0236@1|root,COG0304@1|root,KOG1394@2759|Eukaryota,KOG1748@2759|Eukaryota,38H9Y@33154|Opisthokonta,3BF6J@33208|Metazoa,3CYM9@33213|Bilateria,41XX5@6656|Arthropoda,3SKFX@50557|Insecta,44XVE@7147|Diptera	33208|Metazoa	I	Transferase activity, transferring acyl groups other than amino-acyl groups. It is involved in the biological process described with fatty acid biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	Ketoacyl-synt_C,PP-binding,ketoacyl-synt
k141_9020_1	396588.Tgr7_2002	4.77e-73	233.0	COG2256@1|root,COG2256@2|Bacteria,1MUVS@1224|Proteobacteria,1RPBY@1236|Gammaproteobacteria,1WVV4@135613|Chromatiales	135613|Chromatiales	L	AAA ATPase, central domain protein	-	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA,AAA_assoc_2,MgsA_C,RuvB_N
k141_9678_1	1121374.KB891577_gene3210	7.1e-112	337.0	COG0843@1|root,COG0843@2|Bacteria,1MU7S@1224|Proteobacteria,1RNUX@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B	-	-	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
k141_5389_1	1229909.NSED_09590	2.43e-38	129.0	arCOG08808@1|root,arCOG08808@2157|Archaea,41T95@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_5389_2	436308.Nmar_1792	8.99e-39	142.0	COG0459@1|root,arCOG01257@2157|Archaea,41SDG@651137|Thaumarchaeota	651137|Thaumarchaeota	O	PFAM TCP-1 cpn60 chaperonin family	-	-	-	ko:K22447	-	-	-	-	ko00000,ko03110	-	-	-	Cpn60_TCP1
k141_4152_1	1110502.TMO_3516	4.68e-44	157.0	COG2114@1|root,COG2114@2|Bacteria,1MWHK@1224|Proteobacteria,2TR2J@28211|Alphaproteobacteria,2JQ73@204441|Rhodospirillales	204441|Rhodospirillales	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc
k141_5987_1	1049564.TevJSym_at00760	1.16e-101	309.0	COG3808@1|root,COG3808@2|Bacteria,1MUQ3@1224|Proteobacteria,1RN4K@1236|Gammaproteobacteria,1J5F2@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na( ) movement across the membrane	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase
k141_2919_1	1121859.KB890738_gene3175	1.75e-31	120.0	COG1381@1|root,COG1381@2|Bacteria,4NIBQ@976|Bacteroidetes,47K9Z@768503|Cytophagia	976|Bacteroidetes	L	Involved in DNA repair and RecF pathway recombination	recO	-	-	ko:K03584	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecO_C,RecO_N
k141_9021_1	1007105.PT7_3003	1.19e-97	294.0	COG4266@1|root,COG4266@2|Bacteria,1MXJK@1224|Proteobacteria,2VKRI@28216|Betaproteobacteria,3T765@506|Alcaligenaceae	28216|Betaproteobacteria	F	Allantoicase repeat	alc	-	3.5.3.4	ko:K01477	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R02422	RC00379,RC00712	ko00000,ko00001,ko00002,ko01000	-	-	-	Allantoicase
k141_3496_1	555779.Dthio_PD3543	1.8e-43	157.0	COG2251@1|root,COG2251@2|Bacteria,1QUUG@1224|Proteobacteria,43CSJ@68525|delta/epsilon subdivisions,2X807@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Domain of unknown function(DUF2779)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2779
k141_1064_1	196367.JNFG01000034_gene7522	3.89e-35	134.0	COG5421@1|root,COG5421@2|Bacteria,1R3NX@1224|Proteobacteria,2VZHX@28216|Betaproteobacteria,1K341@119060|Burkholderiaceae	28216|Betaproteobacteria	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
k141_9680_2	1121441.AUCX01000007_gene1206	2.72e-24	94.0	COG4430@1|root,COG4430@2|Bacteria,1QZ57@1224|Proteobacteria,43DEF@68525|delta/epsilon subdivisions,2X8KC@28221|Deltaproteobacteria,2MHIS@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Putative tRNA binding domain	-	-	-	ko:K06878	-	-	-	-	ko00000	-	-	-	tRNA_bind
k141_1065_1	686578.AFFX01000012_gene2042	4.6e-48	167.0	COG0111@1|root,COG0111@2|Bacteria,1N5TD@1224|Proteobacteria,1RMFW@1236|Gammaproteobacteria	1236|Gammaproteobacteria	H	Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate	pdxB	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0033711,GO:0034641,GO:0036001,GO:0036094,GO:0042364,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055114,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	1.1.1.290	ko:K03473	ko00750,ko01100,map00750,map01100	M00124	R04210	RC00084	ko00000,ko00001,ko00002,ko01000	-	-	iZ_1308.Z3582	2-Hacid_dh,2-Hacid_dh_C,DUF3410
k141_2306_1	742766.HMPREF9455_01069	1.76e-49	171.0	COG0649@1|root,COG0649@2|Bacteria,4NF02@976|Bacteroidetes,2FWV4@200643|Bacteroidia,231G8@171551|Porphyromonadaceae	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoD	-	1.6.5.3	ko:K00333	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_49kDa
k141_1142_2	203122.Sde_3099	3.14e-06	50.4	COG1305@1|root,COG4196@1|root,COG1305@2|Bacteria,COG4196@2|Bacteria,1MVAG@1224|Proteobacteria,1RMX2@1236|Gammaproteobacteria,464EZ@72275|Alteromonadaceae	1236|Gammaproteobacteria	E	Putative amidoligase enzyme (DUF2126)	IV02_11925	-	-	-	-	-	-	-	-	-	-	-	Bact_transglu_N,DUF2126,Transglut_core
k141_4233_1	159749.K0R914	3.44e-63	221.0	COG2801@1|root,KOG0017@2759|Eukaryota,2XEDA@2836|Bacillariophyta	159749.K0R914|-	L	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_7296_1	713586.KB900536_gene3059	4e-90	278.0	COG0195@1|root,COG0195@2|Bacteria,1MWT7@1224|Proteobacteria,1RNQS@1236|Gammaproteobacteria,1WVXP@135613|Chromatiales	135613|Chromatiales	K	Participates in both transcription termination and antitermination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	HHH_5,KH_5,NusA_N,S1
k141_9097_1	1415756.JQMY01000001_gene2224	5.96e-96	290.0	COG4603@1|root,COG4603@2|Bacteria,1MX6V@1224|Proteobacteria,2TUGD@28211|Alphaproteobacteria,2PCB4@252301|Oceanicola	28211|Alphaproteobacteria	S	Branched-chain amino acid transport system / permease component	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
k141_2998_1	1049564.TevJSym_an00030	2.22e-76	245.0	COG0737@1|root,COG0737@2|Bacteria,1MX03@1224|Proteobacteria,1RPX3@1236|Gammaproteobacteria,1J7AF@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	F	5'-nucleotidase, C-terminal domain	soxB	-	-	ko:K17224	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	-	-	-	5_nucleotid_C
k141_4234_1	1085623.GNIT_0389	1.14e-102	311.0	COG2509@1|root,COG2509@2|Bacteria,1MV6P@1224|Proteobacteria,1RPTW@1236|Gammaproteobacteria,465F5@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	FAD-dependent dehydrogenases	IV02_08645	-	-	ko:K07137	-	-	-	-	ko00000	-	-	-	Amino_oxidase
k141_5464_1	83219.PM02_03925	5.07e-22	92.0	COG0681@1|root,COG0681@2|Bacteria,1MXUF@1224|Proteobacteria,2TR9N@28211|Alphaproteobacteria,3ZWD4@60136|Sulfitobacter	28211|Alphaproteobacteria	U	Signal peptidase I	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24
k141_5464_2	985054.JQEZ01000002_gene3674	1.81e-80	240.0	COG0736@1|root,COG0736@2|Bacteria,1MZBF@1224|Proteobacteria,2U77S@28211|Alphaproteobacteria,4NBZZ@97050|Ruegeria	28211|Alphaproteobacteria	I	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein	acpS	-	2.7.8.7	ko:K00997	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	-	ACPS
k141_5464_3	371731.Rsw2DRAFT_2263	1.39e-05	46.2	COG0854@1|root,COG0854@2|Bacteria,1MU9W@1224|Proteobacteria,2TTTF@28211|Alphaproteobacteria,1FB2F@1060|Rhodobacter	28211|Alphaproteobacteria	H	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate	pdxJ	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	2.6.99.2	ko:K03474	ko00750,ko01100,map00750,map01100	M00124	R05838	RC01476	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxJ
k141_4847_2	317025.Tcr_1757	2.43e-59	192.0	COG0637@1|root,COG0637@2|Bacteria,1QTT8@1224|Proteobacteria,1T1GC@1236|Gammaproteobacteria,460VF@72273|Thiotrichales	72273|Thiotrichales	S	Haloacid dehalogenase-like hydrolase	-	-	3.1.3.5	ko:K20881	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
k141_2999_1	1282876.BAOK01000001_gene2389	6.35e-57	198.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,2TQRZ@28211|Alphaproteobacteria,4BPTW@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	S	ABC transporter	yheS	GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0008144,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
k141_4894_2	1049564.TevJSym_af00810	3.69e-59	187.0	COG0655@1|root,COG0655@2|Bacteria,1MW7N@1224|Proteobacteria,1S23B@1236|Gammaproteobacteria,1J5TT@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Belongs to the WrbA family	wrbA	-	1.6.5.2	ko:K03809	ko00130,ko01110,map00130,map01110	-	R02964,R03643,R03816	RC00819	ko00000,ko00001,ko01000	-	-	-	FMN_red
k141_9151_1	290397.Adeh_3845	1.99e-49	171.0	COG0312@1|root,COG0312@2|Bacteria,1RBJZ@1224|Proteobacteria,42YBE@68525|delta/epsilon subdivisions,2WUP7@28221|Deltaproteobacteria,2YZ4Y@29|Myxococcales	28221|Deltaproteobacteria	L	Putative modulator of DNA gyrase	-	-	-	ko:K03592	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
k141_2594_1	1250005.PHEL85_2612	4.06e-90	284.0	COG0457@1|root,COG0457@2|Bacteria,4NDTY@976|Bacteroidetes,1HYM1@117743|Flavobacteriia	976|Bacteroidetes	S	Cytochrome c554 and c-prime	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554,HEAT_2,Paired_CXXCH_1,TPR_19,TPR_8
k141_2594_2	1250005.PHEL85_2612	7.99e-31	122.0	COG0457@1|root,COG0457@2|Bacteria,4NDTY@976|Bacteroidetes,1HYM1@117743|Flavobacteriia	976|Bacteroidetes	S	Cytochrome c554 and c-prime	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554,HEAT_2,Paired_CXXCH_1,TPR_19,TPR_8
k141_3820_1	1122599.AUGR01000017_gene3011	6.24e-10	62.8	COG1520@1|root,COG1520@2|Bacteria,1MXIJ@1224|Proteobacteria,1RN4V@1236|Gammaproteobacteria,1XIXJ@135619|Oceanospirillales	135619|Oceanospirillales	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamB	-	-	ko:K17713	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	PQQ_2,PQQ_3
k141_3820_2	90813.JQMT01000001_gene1360	7.24e-28	110.0	COG1160@1|root,COG1160@2|Bacteria,1MU9S@1224|Proteobacteria,1RMSF@1236|Gammaproteobacteria,4604V@72273|Thiotrichales	72273|Thiotrichales	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	-	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
k141_3203_1	1123296.JQKE01000107_gene739	2.49e-05	47.8	COG2377@1|root,COG2377@2|Bacteria,1MV4E@1224|Proteobacteria,2VHCE@28216|Betaproteobacteria,2KPIM@206351|Neisseriales	206351|Neisseriales	F	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling	anmK	-	2.7.1.170	ko:K09001	-	-	-	-	ko00000,ko01000	-	-	-	AnmK,DAGK_prokar
k141_3203_2	1046724.KB889828_gene2833	2.41e-34	130.0	COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,1RM7S@1236|Gammaproteobacteria,4640S@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	COG0739 Membrane proteins related to metalloendopeptidases	yebA	-	-	-	-	-	-	-	-	-	-	-	OapA,OapA_N,Peptidase_M23
k141_6908_1	247639.MGP2080_15509	3.69e-09	55.5	COG0494@1|root,COG0494@2|Bacteria,1RCZM@1224|Proteobacteria,1RS3S@1236|Gammaproteobacteria,1JAKZ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	L	NUDIX domain	mutT	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008413,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017110,GO:0030145,GO:0033554,GO:0034641,GO:0035539,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044715,GO:0044716,GO:0046483,GO:0046872,GO:0046914,GO:0047429,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	iE2348C_1286.E2348C_0104,iSDY_1059.SDY_0129	NUDIX,NUDIX_4,TMP-TENI
k141_6908_2	715451.ambt_02245	2.23e-49	177.0	COG0653@1|root,COG0653@2|Bacteria,1MUJZ@1224|Proteobacteria,1RM9M@1236|Gammaproteobacteria,464S6@72275|Alteromonadaceae	1236|Gammaproteobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	GO:0000166,GO:0002790,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006457,GO:0006605,GO:0006810,GO:0006886,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032940,GO:0032991,GO:0033036,GO:0033220,GO:0034613,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042802,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061077,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
k141_8118_1	391593.RCCS2_15969	4.38e-32	121.0	COG0849@1|root,COG0849@2|Bacteria,1MUSR@1224|Proteobacteria,2TQZB@28211|Alphaproteobacteria,2P1E8@2433|Roseobacter	28211|Alphaproteobacteria	D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring	ftsA	-	-	ko:K03590	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036,ko04812	-	-	-	FtsA,SHS2_FTSA
k141_8118_2	391593.RCCS2_15974	3.29e-28	111.0	COG0206@1|root,COG0206@2|Bacteria,1MV2X@1224|Proteobacteria,2TS1Q@28211|Alphaproteobacteria,2P1WU@2433|Roseobacter	28211|Alphaproteobacteria	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
k141_4451_1	296591.Bpro_4411	5.99e-33	127.0	COG0583@1|root,COG0583@2|Bacteria,1MX2A@1224|Proteobacteria,2VQNG@28216|Betaproteobacteria,4AIZS@80864|Comamonadaceae	28216|Betaproteobacteria	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
k141_8119_2	1144672.F966_00451	5.2e-14	73.2	COG0399@1|root,COG0399@2|Bacteria,1MUMJ@1224|Proteobacteria,1RSDY@1236|Gammaproteobacteria,3NKKZ@468|Moraxellaceae	1236|Gammaproteobacteria	M	Putative transposase	-	-	-	-	-	-	-	-	-	-	-	-	Y2_Tnp,Zn_Tnp_IS91
k141_1985_1	367336.OM2255_13037	2.82e-05	45.1	COG1638@1|root,COG1638@2|Bacteria,1PG0D@1224|Proteobacteria,2TTUQ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	transport system periplasmic component	-	-	-	-	-	-	-	-	-	-	-	-	DctP
k141_1985_2	1288298.rosmuc_00541	6.24e-71	219.0	COG3090@1|root,COG3090@2|Bacteria,1NK6X@1224|Proteobacteria,2TV38@28211|Alphaproteobacteria,46Q1H@74030|Roseovarius	28211|Alphaproteobacteria	G	Tripartite ATP-independent periplasmic transporters, DctQ component	-	-	-	-	-	-	-	-	-	-	-	-	DctQ
k141_8735_1	317025.Tcr_0817	2.52e-45	148.0	COG0838@1|root,COG0838@2|Bacteria,1RGUT@1224|Proteobacteria,1S644@1236|Gammaproteobacteria,460WP@72273|Thiotrichales	72273|Thiotrichales	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoA	-	1.6.5.3	ko:K00330	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q4
k141_8735_2	187272.Mlg_1969	6.24e-60	187.0	COG0377@1|root,COG0377@2|Bacteria,1MUI2@1224|Proteobacteria,1RP4R@1236|Gammaproteobacteria,1WW6I@135613|Chromatiales	135613|Chromatiales	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoB	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
k141_125_1	338966.Ppro_3708	6.56e-42	148.0	COG3677@1|root,COG3677@2|Bacteria,1MXYX@1224|Proteobacteria	1224|Proteobacteria	L	Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS1595,Zn_Tnp_IS1595
k141_1368_1	517417.Cpar_1700	2.86e-111	333.0	COG3004@1|root,COG3004@2|Bacteria,1FDWE@1090|Chlorobi	1090|Chlorobi	P	) H( ) antiporter that extrudes sodium in exchange for external protons	nhaA	-	-	ko:K03313	-	-	-	-	ko00000,ko02000	2.A.33.1	-	-	Na_H_antiport_1
k141_2597_1	396588.Tgr7_0274	3.65e-18	89.7	29DE2@1|root,300BX@2|Bacteria,1NC7M@1224|Proteobacteria,1SFWA@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_5064_1	246200.SPO2033	2.52e-99	313.0	COG0013@1|root,COG0013@2|Bacteria,1MU9A@1224|Proteobacteria,2TQV4@28211|Alphaproteobacteria,4NB7C@97050|Ruegeria	28211|Alphaproteobacteria	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
k141_1369_1	1049564.TevJSym_ag01050	8.42e-76	231.0	COG0242@1|root,COG0242@2|Bacteria,1RA2P@1224|Proteobacteria,1S247@1236|Gammaproteobacteria,1J5V6@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
k141_6299_1	411684.HPDFL43_12653	4.5e-71	231.0	COG5598@1|root,COG5598@2|Bacteria,1MWJN@1224|Proteobacteria,2TR0V@28211|Alphaproteobacteria,43H6V@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	H	Trimethylamine methyltransferase	mttB2	-	2.1.1.250	ko:K14083	ko00680,ko01120,ko01200,map00680,map01120,map01200	M00563	R09124,R10016	RC00035,RC00732,RC01144,RC02984	ko00000,ko00001,ko00002,ko01000	-	-	-	MTTB
k141_8736_1	488538.SAR116_2173	1.44e-145	433.0	COG0404@1|root,COG0665@1|root,COG0404@2|Bacteria,COG0665@2|Bacteria,1MUXJ@1224|Proteobacteria,2TRGS@28211|Alphaproteobacteria,4BR7M@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	C	Belongs to the GcvT family	-	-	1.5.8.4	ko:K00315	ko00260,ko01100,map00260,map01100	-	R01565	RC00181	ko00000,ko00001,ko01000	-	-	-	DAO,FAO_M,GCV_T,GCV_T_C
k141_9382_1	9597.XP_008950705.1	2.66e-42	157.0	COG0458@1|root,KOG0370@2759|Eukaryota,38CAC@33154|Opisthokonta,3B9FF@33208|Metazoa,3CS9A@33213|Bilateria,4804V@7711|Chordata,490QX@7742|Vertebrata,3J7SX@40674|Mammalia,35JF3@314146|Euarchontoglires,4MB3P@9443|Primates,4N0A5@9604|Hominidae	33208|Metazoa	F	Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase	CAD	GO:0000050,GO:0000052,GO:0000166,GO:0001882,GO:0001884,GO:0002119,GO:0002134,GO:0002164,GO:0003674,GO:0003824,GO:0004070,GO:0004087,GO:0004088,GO:0004151,GO:0004672,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005829,GO:0006082,GO:0006139,GO:0006206,GO:0006207,GO:0006213,GO:0006220,GO:0006221,GO:0006228,GO:0006464,GO:0006468,GO:0006520,GO:0006525,GO:0006526,GO:0006541,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007275,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009208,GO:0009209,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009605,GO:0009653,GO:0009719,GO:0009725,GO:0009791,GO:0009887,GO:0009987,GO:0009991,GO:0010033,GO:0010243,GO:0016053,GO:0016301,GO:0016310,GO:0016363,GO:0016597,GO:0016740,GO:0016741,GO:0016743,GO:0016772,GO:0016773,GO:0016787,GO:0016810,GO:0016812,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0017144,GO:0018107,GO:0018130,GO:0018193,GO:0018210,GO:0019103,GO:0019240,GO:0019438,GO:0019538,GO:0019627,GO:0019637,GO:0019693,GO:0019752,GO:0019856,GO:0019899,GO:0022612,GO:0030424,GO:0030554,GO:0031406,GO:0031667,GO:0031974,GO:0031981,GO:0032501,GO:0032502,GO:0032549,GO:0032551,GO:0032553,GO:0032555,GO:0032557,GO:0032559,GO:0032868,GO:0032991,GO:0033267,GO:0034399,GO:0034404,GO:0034641,GO:0034654,GO:0035295,GO:0035639,GO:0036094,GO:0036211,GO:0036477,GO:0042221,GO:0042455,GO:0042594,GO:0042802,GO:0042995,GO:0043005,GO:0043025,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043177,GO:0043195,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043434,GO:0043436,GO:0043603,GO:0043604,GO:0043679,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0044297,GO:0044306,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044456,GO:0044463,GO:0044464,GO:0045202,GO:0046051,GO:0046112,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046394,GO:0046483,GO:0046777,GO:0046872,GO:0046914,GO:0048513,GO:0048565,GO:0048731,GO:0048732,GO:0048856,GO:0050896,GO:0055086,GO:0055123,GO:0060465,GO:0070013,GO:0070335,GO:0070406,GO:0071704,GO:0071941,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:0097458,GO:0098793,GO:0120025,GO:0120038,GO:0140096,GO:0150034,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901652,GO:1901657,GO:1901659,GO:1901698,GO:1901700,GO:1905905	2.1.3.2,3.5.2.3,6.3.5.5	ko:K11540	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R01397,R01993,R10948,R10949	RC00002,RC00010,RC00043,RC00064,RC00632,RC02750,RC02798,RC02850,RC03314	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	Amidohydro_1,CPSase_L_D2,CPSase_L_D3,CPSase_sm_chain,GATase,MGS,OTCace,OTCace_N
k141_747_1	945021.TEH_06310	1.23e-69	224.0	COG0624@1|root,COG0624@2|Bacteria,1TR99@1239|Firmicutes,4HDRQ@91061|Bacilli,4B1KI@81852|Enterococcaceae	91061|Bacilli	E	Peptidase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
k141_7491_1	159749.K0SZZ0	2.28e-42	160.0	COG2801@1|root,KOG0017@2759|Eukaryota,2XHT0@2836|Bacillariophyta	159749.K0SZZ0|-	O	transposition, RNA-mediated	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_8121_1	264402.Cagra.5120s0021.1.p	2.95e-89	275.0	COG1290@1|root,KOG4663@2759|Eukaryota,37PDF@33090|Viridiplantae,3GF4E@35493|Streptophyta	35493|Streptophyta	C	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis	cob	-	-	ko:K00412	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002,ko03029	-	-	-	Cytochrom_B_C,Cytochrome_B
k141_4454_1	1116375.VEJY3_22691	2.26e-39	132.0	COG2963@1|root,COG2963@2|Bacteria,1N04F@1224|Proteobacteria,1S6GJ@1236|Gammaproteobacteria,1Y27B@135623|Vibrionales	135623|Vibrionales	L	Transposase	-	-	-	ko:K07483	-	-	-	-	ko00000	-	-	-	HTH_Tnp_1
k141_4454_2	1122197.ATWI01000009_gene1620	4.14e-29	110.0	COG2801@1|root,COG2801@2|Bacteria,1MVXQ@1224|Proteobacteria,1RPEW@1236|Gammaproteobacteria,467PH@72275|Alteromonadaceae	1236|Gammaproteobacteria	L	COG2801 Transposase and inactivated derivatives	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve
k141_1988_1	1123371.ATXH01000012_gene1415	3.22e-51	179.0	COG0442@1|root,COG0442@2|Bacteria,2GH47@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS	proS	-	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_edit
k141_2599_1	1121904.ARBP01000003_gene6352	1.04e-87	272.0	COG2610@1|root,COG2610@2|Bacteria,4NJ5B@976|Bacteroidetes,47K2S@768503|Cytophagia	976|Bacteroidetes	EG	PFAM Gluconate transporter	-	-	-	ko:K03299	-	-	-	-	ko00000,ko02000	2.A.8	-	-	GntP_permease
k141_3207_1	998674.ATTE01000001_gene3388	1.76e-29	108.0	2CQ1K@1|root,32SKA@2|Bacteria,1N0TP@1224|Proteobacteria,1T00Z@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Tripartite tricarboxylate transporter TctB family	-	-	-	-	-	-	-	-	-	-	-	-	TctB
k141_3207_2	388401.RB2150_05838	3.43e-53	176.0	COG3181@1|root,COG3181@2|Bacteria,1MXEX@1224|Proteobacteria,2TTSX@28211|Alphaproteobacteria,3ZGPR@58840|unclassified Rhodobacteraceae	28211|Alphaproteobacteria	S	protein conserved in bacteria	-	-	-	ko:K07795	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.80.1	-	-	TctC
k141_1989_1	1500890.JQNL01000001_gene3246	1.35e-40	134.0	COG0361@1|root,COG0361@2|Bacteria,1MZFU@1224|Proteobacteria,1S8WZ@1236|Gammaproteobacteria,1X7HF@135614|Xanthomonadales	135614|Xanthomonadales	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
k141_5681_1	1250232.JQNJ01000001_gene250	4.56e-93	283.0	COG1730@1|root,COG1730@2|Bacteria,4NHZT@976|Bacteroidetes,1HZM3@117743|Flavobacteriia	976|Bacteroidetes	O	unfolded protein binding	-	-	-	-	-	-	-	-	-	-	-	-	Porin_O_P
k141_7492_1	1121875.KB907551_gene965	1.75e-53	173.0	28KEX@1|root,2ZA14@2|Bacteria,4PAQ1@976|Bacteroidetes,1I8NT@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_2600_1	123214.PERMA_0680	8.78e-09	55.8	COG1136@1|root,COG1136@2|Bacteria,2G3W9@200783|Aquificae	200783|Aquificae	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
k141_2600_2	1283300.ATXB01000001_gene1556	2.24e-05	50.8	COG0577@1|root,COG0577@2|Bacteria,1PBKH@1224|Proteobacteria,1T1FT@1236|Gammaproteobacteria,1XEGW@135618|Methylococcales	135618|Methylococcales	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
k141_5066_1	1157708.KB907463_gene734	5.03e-91	278.0	COG5008@1|root,COG5008@2|Bacteria,1QTTX@1224|Proteobacteria,2VIWS@28216|Betaproteobacteria,4AB13@80864|Comamonadaceae	28216|Betaproteobacteria	NU	PFAM Type II secretion system protein E	pilU	-	-	ko:K02670	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
k141_5066_2	768671.ThimaDRAFT_2549	4.83e-05	45.4	COG5008@1|root,COG5008@2|Bacteria,1QTTX@1224|Proteobacteria,1RN0B@1236|Gammaproteobacteria,1WX4M@135613|Chromatiales	135613|Chromatiales	NU	PFAM Type II secretion system protein E	-	-	-	ko:K02670	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
k141_8738_1	1279019.ARQK01000039_gene457	2.36e-106	323.0	COG4108@1|root,COG4108@2|Bacteria,1MU7X@1224|Proteobacteria,1RMFT@1236|Gammaproteobacteria,1WX2I@135613|Chromatiales	135613|Chromatiales	J	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP	prfC	-	-	ko:K02837	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,RF3_C
k141_1990_1	1288298.rosmuc_03228	1.07e-53	176.0	COG1526@1|root,COG1526@2|Bacteria,1MY28@1224|Proteobacteria,2VFYH@28211|Alphaproteobacteria,46PK3@74030|Roseovarius	28211|Alphaproteobacteria	C	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH	fdhD	-	-	ko:K02379	-	-	-	-	ko00000	-	-	-	FdhD-NarQ
k141_1990_2	1123501.KB902312_gene2580	0.000191	43.5	COG1296@1|root,COG1296@2|Bacteria,1MVGN@1224|Proteobacteria,2TVIA@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	branched-chain amino acid permease (azaleucine resistance)	azlC	-	-	-	-	-	-	-	-	-	-	-	AzlC
k141_9385_1	880073.Calab_1929	3.2e-46	164.0	COG2204@1|root,COG2204@2|Bacteria,2NNPN@2323|unclassified Bacteria	2|Bacteria	T	COGs COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains	-	-	-	ko:K02481,ko:K07714	ko02020,map02020	M00500	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
k141_5067_1	713586.KB900536_gene2898	1.94e-70	226.0	COG0247@1|root,COG0247@2|Bacteria,1MWTK@1224|Proteobacteria,1RQ9M@1236|Gammaproteobacteria,1WX1I@135613|Chromatiales	135613|Chromatiales	C	Cysteine-rich domain	-	-	-	-	-	-	-	-	-	-	-	-	CCG
k141_3209_1	640081.Dsui_3398	5.46e-82	255.0	COG2826@1|root,COG2826@2|Bacteria,1PP49@1224|Proteobacteria,2VI0E@28216|Betaproteobacteria,2KVNH@206389|Rhodocyclales	206389|Rhodocyclales	L	PFAM Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_38,rve
k141_131_1	754477.Q7C_243	9.21e-53	177.0	COG0530@1|root,COG0530@2|Bacteria,1MU3R@1224|Proteobacteria,1RMRD@1236|Gammaproteobacteria,45ZX2@72273|Thiotrichales	72273|Thiotrichales	P	PFAM sodium calcium exchanger	-	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
k141_9386_1	983548.Krodi_0113	5.84e-60	210.0	COG1361@1|root,COG2304@1|root,COG3209@1|root,COG5384@1|root,COG1361@2|Bacteria,COG2304@2|Bacteria,COG3209@2|Bacteria,COG5384@2|Bacteria,4PKBQ@976|Bacteroidetes,1IJ7S@117743|Flavobacteriia,37E64@326319|Dokdonia	976|Bacteroidetes	M	SPTR CHU large protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,DUF11,HYR,SdrD_B,SprB
k141_2603_1	391593.RCCS2_11492	9.47e-90	266.0	COG0088@1|root,COG0088@2|Bacteria,1MXPF@1224|Proteobacteria,2TRUT@28211|Alphaproteobacteria,2P1R4@2433|Roseobacter	28211|Alphaproteobacteria	J	Forms part of the polypeptide exit tunnel	rplD	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02926	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L4
k141_6917_1	1333998.M2A_2826	2.34e-83	263.0	COG0539@1|root,COG0539@2|Bacteria,1MVAV@1224|Proteobacteria,2TQPV@28211|Alphaproteobacteria,4BPNS@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	J	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence	rpsA	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
k141_1992_1	89187.ISM_13990	2.07e-102	314.0	COG0441@1|root,COG0441@2|Bacteria,1MUP2@1224|Proteobacteria,2TQWI@28211|Alphaproteobacteria,46PNQ@74030|Roseovarius	28211|Alphaproteobacteria	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	-	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD
k141_2604_1	1110502.TMO_0632	2.91e-67	224.0	COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,2TS8E@28211|Alphaproteobacteria,2JPNR@204441|Rhodospirillales	204441|Rhodospirillales	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	1.1.1.35	ko:K07516	ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212	M00087	R01975,R04737,R04739,R04741,R04743,R04745,R04748,R05305	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000	-	-	-	3HCDH,3HCDH_N,ECH_1
k141_4459_1	1238182.C882_2454	4.47e-75	235.0	COG0414@1|root,COG0414@2|Bacteria,1MV1S@1224|Proteobacteria,2TS2D@28211|Alphaproteobacteria,2JQ4D@204441|Rhodospirillales	204441|Rhodospirillales	H	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate	panC	-	6.3.2.1	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R02473	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_ligase
k141_6305_1	391593.RCCS2_02023	8.52e-135	392.0	COG0174@1|root,COG0174@2|Bacteria,1MUGQ@1224|Proteobacteria,2TSCR@28211|Alphaproteobacteria,2P20Y@2433|Roseobacter	28211|Alphaproteobacteria	H	glutamine synthetase	glnA	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
k141_3829_1	472175.EL18_02129	1.65e-05	45.8	COG0766@1|root,COG0766@2|Bacteria,1MUH7@1224|Proteobacteria,2TRPH@28211|Alphaproteobacteria,43HNN@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
k141_3829_2	1446473.JHWH01000052_gene2515	3.11e-23	96.3	2CN5Z@1|root,32SGB@2|Bacteria,1N1FB@1224|Proteobacteria,2UBV1@28211|Alphaproteobacteria,2PWMB@265|Paracoccus	28211|Alphaproteobacteria	S	Protein of unknown function (DUF2948)	MA20_21100	-	-	-	-	-	-	-	-	-	-	-	DUF2948
k141_6919_1	1123393.KB891332_gene2686	9.66e-46	157.0	COG1721@1|root,COG1721@2|Bacteria,1Q7RR@1224|Proteobacteria,2VNZY@28216|Betaproteobacteria	28216|Betaproteobacteria	S	conserved protein (some members contain a von Willebrand factor type A (vWA) domain)	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
k141_6919_2	438753.AZC_3381	1.76e-07	52.4	COG0714@1|root,COG0714@2|Bacteria,1MUFN@1224|Proteobacteria,2TT2Y@28211|Alphaproteobacteria,3F0DP@335928|Xanthobacteraceae	28211|Alphaproteobacteria	S	ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
k141_7494_1	1469557.JSWF01000033_gene1606	6.97e-82	270.0	COG0308@1|root,COG0308@2|Bacteria,4NF3R@976|Bacteroidetes,1HXJJ@117743|Flavobacteriia	976|Bacteroidetes	E	Peptidase family M1 domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
k141_8740_1	159749.K0TFP4	1.13e-26	116.0	2D2SH@1|root,2SNVM@2759|Eukaryota	2759|Eukaryota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Helitron_like_N
k141_2074_3	159749.E7BWM9	4.25e-34	118.0	COG0198@1|root,KOG1708@2759|Eukaryota	2759|Eukaryota	J	structural constituent of ribosome	rpl24	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009507,GO:0009526,GO:0009532,GO:0009536,GO:0009570,GO:0009657,GO:0009941,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022625,GO:0022626,GO:0031967,GO:0031975,GO:0032544,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02895	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KOW,ribosomal_L24
k141_7006_1	1049564.TevJSym_bb00130	7.11e-37	143.0	COG5009@1|root,COG5009@2|Bacteria,1MU5A@1224|Proteobacteria,1RM7J@1236|Gammaproteobacteria,1J4BX@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	penicillin-binding protein	mrcA	GO:0000270,GO:0003674,GO:0003824,GO:0004180,GO:0004185,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006023,GO:0006024,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0008360,GO:0008658,GO:0008955,GO:0009002,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0016758,GO:0016787,GO:0017171,GO:0019538,GO:0022603,GO:0022604,GO:0030203,GO:0031224,GO:0031226,GO:0031406,GO:0033218,GO:0033293,GO:0034645,GO:0036094,GO:0042221,GO:0042546,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044425,GO:0044459,GO:0044464,GO:0046677,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051128,GO:0065007,GO:0065008,GO:0070008,GO:0070011,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:0140096,GO:1901135,GO:1901137,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	PCB_OB,Transgly,Transpeptidase
k141_218_2	159749.E7BWP3	3.91e-78	233.0	COG0048@1|root,KOG1750@2759|Eukaryota	2759|Eukaryota	J	structural constituent of ribosome	rps12	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009507,GO:0009532,GO:0009534,GO:0009536,GO:0009570,GO:0009579,GO:0009987,GO:0010467,GO:0019538,GO:0031976,GO:0031984,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02950,ko:K02992	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosom_S12_S23
k141_7570_1	870187.Thini_0394	2.51e-58	182.0	COG0278@1|root,COG0278@2|Bacteria,1MZ4V@1224|Proteobacteria,1S640@1236|Gammaproteobacteria,460ZB@72273|Thiotrichales	72273|Thiotrichales	C	Belongs to the glutaredoxin family. Monothiol subfamily	grxD	-	-	ko:K07390	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Glutaredoxin
k141_8820_1	1122599.AUGR01000012_gene900	9.29e-70	219.0	arCOG03638@1|root,2Z8W3@2|Bacteria,1N2PH@1224|Proteobacteria,1RMI8@1236|Gammaproteobacteria,1XHVP@135619|Oceanospirillales	135619|Oceanospirillales	S	Protein of unknown function (DUF1538)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1538
k141_3294_2	27923.ML13539a-PA	2.28e-08	66.2	COG2801@1|root,KOG0017@2759|Eukaryota,38DPC@33154|Opisthokonta,3BS5J@33208|Metazoa	33208|Metazoa	L	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	RVT_2,rve
k141_7007_1	857087.Metme_0873	3.72e-135	404.0	COG0296@1|root,COG0296@2|Bacteria,1QTVN@1224|Proteobacteria,1RQSK@1236|Gammaproteobacteria,1XEQR@135618|Methylococcales	135618|Methylococcales	G	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position	glgB	-	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_48
k141_5769_1	648757.Rvan_3425	1.57e-65	213.0	COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,2TS06@28211|Alphaproteobacteria,3N640@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	E	Aminotransferase class I and II	aspB	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
k141_3074_2	391589.RGAI101_852	1.82e-05	47.4	COG0697@1|root,COG0697@2|Bacteria,1R67M@1224|Proteobacteria,2U7N9@28211|Alphaproteobacteria	28211|Alphaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
k141_4299_1	1380387.JADM01000004_gene2844	2.35e-167	478.0	COG0055@1|root,COG0055@2|Bacteria,1MUFU@1224|Proteobacteria,1RN6U@1236|Gammaproteobacteria,1XIMC@135619|Oceanospirillales	135619|Oceanospirillales	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
k141_2453_2	159749.E7BWH7	2.54e-10	56.2	2E9KB@1|root,2SFXQ@2759|Eukaryota	2759|Eukaryota	J	Ribosomal protein L35	rpl35	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009536,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464	-	-	-	-	-	-	-	-	-	-	Ribosomal_L35p
k141_5545_1	1121875.KB907548_gene1369	1.39e-39	148.0	2EAVS@1|root,334X4@2|Bacteria,4NWJY@976|Bacteroidetes,1I6CS@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_1840_1	391593.RCCS2_09944	7.84e-90	277.0	COG4424@1|root,COG4424@2|Bacteria,1QGYC@1224|Proteobacteria,2TRKU@28211|Alphaproteobacteria,2P21H@2433|Roseobacter	28211|Alphaproteobacteria	S	Sulfotransferase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_2
k141_6150_1	272568.GDI2093	5.71e-54	174.0	COG3415@1|root,COG3415@2|Bacteria,1NBHM@1224|Proteobacteria,2UAIZ@28211|Alphaproteobacteria,2JTA0@204441|Rhodospirillales	204441|Rhodospirillales	L	Winged helix-turn helix	-	-	-	-	-	-	-	-	-	-	-	-	HTH_28,HTH_29,HTH_32,HTH_33
k141_6150_2	316056.RPC_4057	2.12e-80	243.0	COG3335@1|root,COG3335@2|Bacteria,1RDBN@1224|Proteobacteria,2VFA9@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	transposable element conserved	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3
k141_601_1	159749.K0RTY6	8.2e-159	449.0	COG0464@1|root,KOG0730@2759|Eukaryota,2XFQN@2836|Bacillariophyta	2836|Bacillariophyta	O	ATPase family associated with various cellular activities (AAA)	cbbX	-	-	-	-	-	-	-	-	-	-	-	AAA
k141_3649_1	159749.E7BWF3	5.64e-40	150.0	2CACG@1|root,2RWZ1@2759|Eukaryota,2XE6M@2836|Bacillariophyta	2836|Bacillariophyta	S	Uncharacterised protein family	ycf90	-	-	-	-	-	-	-	-	-	-	-	YCF90
k141_3649_5	159749.K0S4J3	8.33e-100	292.0	2CNI2@1|root,2QWGG@2759|Eukaryota,2XE1A@2836|Bacillariophyta	2836|Bacillariophyta	C	Seems to be required for the assembly of the photosystem I complex	ycf4	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009536,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464	-	-	-	-	-	-	-	-	-	-	Ycf4
k141_8580_1	1207063.P24_02221	5.78e-108	322.0	COG0045@1|root,COG0045@2|Bacteria,1MVCE@1224|Proteobacteria,2TRXK@28211|Alphaproteobacteria,2JPG4@204441|Rhodospirillales	204441|Rhodospirillales	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit	sucC	-	6.2.1.5	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,Ligase_CoA
k141_9181_1	1198232.CYCME_0743	3.18e-156	446.0	COG0050@1|root,COG0050@2|Bacteria,1MVC0@1224|Proteobacteria,1RMYX@1236|Gammaproteobacteria,45ZSW@72273|Thiotrichales	72273|Thiotrichales	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
k141_3076_1	172045.KS04_13080	1.22e-12	72.8	COG0578@1|root,COG0578@2|Bacteria,4NEYG@976|Bacteroidetes,1HZVQ@117743|Flavobacteriia,34PZ1@308865|Elizabethkingia	976|Bacteroidetes	C	C-terminal domain of alpha-glycerophosphate oxidase	glpD	-	1.1.5.3	ko:K00111	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	DAO,DAO_C
k141_1841_1	1408419.JHYG01000002_gene1088	1.65e-72	238.0	COG5265@1|root,COG5265@2|Bacteria,1NSKS@1224|Proteobacteria,2UQAG@28211|Alphaproteobacteria,2JR6D@204441|Rhodospirillales	204441|Rhodospirillales	V	COG5265 ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
k141_4300_1	530564.Psta_0876	2.63e-70	220.0	2DKJT@1|root,309RD@2|Bacteria,2J13B@203682|Planctomycetes	203682|Planctomycetes	S	Chlorite dismutase	-	-	-	-	-	-	-	-	-	-	-	-	Chlor_dismutase
k141_4918_1	1415780.JPOG01000001_gene3302	3.27e-09	65.1	COG2911@1|root,COG2911@2|Bacteria,1MUVD@1224|Proteobacteria,1RMMF@1236|Gammaproteobacteria,1X41H@135614|Xanthomonadales	135614|Xanthomonadales	S	Pathogenicity protein	-	-	-	ko:K09800	-	-	-	-	ko00000,ko02000	-	-	-	TamB
k141_3650_1	196367.JNFG01000020_gene4833	3.08e-16	78.2	COG0665@1|root,COG0665@2|Bacteria,1MU7M@1224|Proteobacteria,2VPYG@28216|Betaproteobacteria,1JZQX@119060|Burkholderiaceae	28216|Betaproteobacteria	E	fad dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
k141_3650_2	1207063.P24_17837	6.21e-24	102.0	COG0154@1|root,COG0154@2|Bacteria,1MW3Z@1224|Proteobacteria,2TS56@28211|Alphaproteobacteria,2JR2A@204441|Rhodospirillales	204441|Rhodospirillales	J	Amidase	-	-	3.5.1.4	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	-	R02540,R03096,R03180,R03909,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000	-	-	-	Amidase
k141_9182_1	999549.KI421513_gene1948	6.87e-71	237.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,2TRJF@28211|Alphaproteobacteria,280B9@191028|Leisingera	28211|Alphaproteobacteria	L	Helix-hairpin-helix class 2 (Pol1 family) motifs	polA	GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
k141_603_1	627192.SLG_21140	1.89e-95	282.0	COG3335@1|root,COG3335@2|Bacteria,1P76X@1224|Proteobacteria,2U16U@28211|Alphaproteobacteria,2K5DS@204457|Sphingomonadales	204457|Sphingomonadales	L	Transposase or inactivated derivative	-	-	-	ko:K07494	-	-	-	-	ko00000	-	-	-	DDE_3
k141_7377_1	1122599.AUGR01000001_gene162	2.43e-10	64.3	COG1999@1|root,COG1999@2|Bacteria,1PC4H@1224|Proteobacteria,1SWXI@1236|Gammaproteobacteria,1XM93@135619|Oceanospirillales	135619|Oceanospirillales	S	signal sequence binding	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_7377_2	1123261.AXDW01000009_gene76	1.19e-06	50.4	COG0109@1|root,COG0109@2|Bacteria,1MW3S@1224|Proteobacteria,1RNHC@1236|Gammaproteobacteria,1X3GV@135614|Xanthomonadales	135614|Xanthomonadales	O	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group	cyoE	GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.141	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	M00154	R07411	RC01786	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	-	-	-	UbiA
k141_7943_1	313598.MED152_13374	2.64e-44	147.0	COG0454@1|root,COG0456@2|Bacteria,4NNG9@976|Bacteroidetes,1I23X@117743|Flavobacteriia,3VWER@52959|Polaribacter	976|Bacteroidetes	K	Acetyltransferase (GNAT) domain	yjgM	-	-	ko:K03828	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_1
k141_9822_1	1265313.HRUBRA_02349	2.33e-24	106.0	COG2931@1|root,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria	1224|Proteobacteria	Q	COG2931, RTX toxins and related Ca2 -binding proteins	aprA	GO:0003674,GO:0003824,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009405,GO:0010467,GO:0016485,GO:0016787,GO:0019538,GO:0031638,GO:0043170,GO:0044238,GO:0044419,GO:0051604,GO:0051704,GO:0071704,GO:0140096,GO:1901564	3.4.24.40	ko:K01406	ko01503,map01503	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	P_proprotein,Peptidase_M10,Peptidase_M10_C,Peptidase_S8,Reprolysin_4,Reprolysin_5
k141_2458_1	203122.Sde_2263	9.18e-62	197.0	28I6Z@1|root,2Z89U@2|Bacteria,1R8YM@1224|Proteobacteria,1S0GG@1236|Gammaproteobacteria,467DP@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	von Willebrand factor (vWF) type A domain	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_4303_1	1237149.C900_03511	2.43e-56	186.0	COG1960@1|root,COG1960@2|Bacteria,4NEHA@976|Bacteroidetes,47K4J@768503|Cytophagia	976|Bacteroidetes	I	acyl-CoA dehydrogenase	acdA	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
k141_4920_1	388739.RSK20926_18232	2.94e-67	209.0	COG0629@1|root,COG0629@2|Bacteria,1RCWT@1224|Proteobacteria,2U5BZ@28211|Alphaproteobacteria,2P2VX@2433|Roseobacter	28211|Alphaproteobacteria	L	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism	ssb	GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
k141_2459_1	1168065.DOK_17190	4.7e-36	129.0	COG2003@1|root,COG2003@2|Bacteria,1MXZ5@1224|Proteobacteria,1RP86@1236|Gammaproteobacteria,1J57Q@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	E	Belongs to the UPF0758 family	radC	GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360	-	ko:K03630	-	-	-	-	ko00000	-	-	-	RadC
k141_2459_2	1208321.D104_08015	0.000509	42.0	COG0452@1|root,COG0452@2|Bacteria,1MVQP@1224|Proteobacteria,1RMKQ@1236|Gammaproteobacteria,1XIHN@135619|Oceanospirillales	135619|Oceanospirillales	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	coaBC	-	4.1.1.36,6.3.2.5	ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
k141_1843_1	314230.DSM3645_08952	0.00039	42.0	COG2104@1|root,COG2104@2|Bacteria,2J1D0@203682|Planctomycetes	203682|Planctomycetes	H	Thiamine biosynthesis	-	-	-	ko:K03154	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
k141_1843_2	552396.HMPREF0863_01118	4.39e-17	84.7	COG0072@1|root,COG0072@2|Bacteria,1TP98@1239|Firmicutes,3VP34@526524|Erysipelotrichia	526524|Erysipelotrichia	J	Psort location Cytoplasmic, score	pheT	-	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
k141_3654_1	472759.Nhal_0269	1.95e-78	243.0	COG2890@1|root,COG2890@2|Bacteria,1MX8Q@1224|Proteobacteria,1RPHQ@1236|Gammaproteobacteria,1WWX2@135613|Chromatiales	135613|Chromatiales	J	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue	prmB	-	2.1.1.298	ko:K07320	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03009	-	-	-	MTS
k141_7946_1	631362.Thi970DRAFT_01521	9.03e-95	285.0	COG0152@1|root,COG0152@2|Bacteria,1MUR9@1224|Proteobacteria,1RNNY@1236|Gammaproteobacteria,1WVZH@135613|Chromatiales	135613|Chromatiales	F	SAICAR synthetase	purC	-	6.3.2.6	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04591	RC00064,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	SAICAR_synt
k141_9185_1	748247.AZKH_1503	2.36e-83	261.0	COG1690@1|root,COG1690@2|Bacteria,1MUHA@1224|Proteobacteria,2VJ89@28216|Betaproteobacteria,2KZ3A@206389|Rhodocyclales	206389|Rhodocyclales	S	tRNA-splicing ligase RtcB	-	-	6.5.1.3	ko:K14415	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RtcB
k141_7947_1	1231190.NA8A_19333	4.44e-98	303.0	COG0465@1|root,COG0465@2|Bacteria,1MU6J@1224|Proteobacteria,2TRNK@28211|Alphaproteobacteria,43GXZ@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	-	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
k141_4305_1	488538.SAR116_1537	1.43e-77	239.0	COG1346@1|root,COG1346@2|Bacteria,1MV81@1224|Proteobacteria,2TSP3@28211|Alphaproteobacteria,4BQ8J@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	M	LrgB-like family	-	-	-	-	-	-	-	-	-	-	-	-	LrgB
k141_4922_1	391593.RCCS2_01753	4.42e-45	146.0	2C5FY@1|root,311X9@2|Bacteria,1Q4IC@1224|Proteobacteria,2VB06@28211|Alphaproteobacteria,2P3X6@2433|Roseobacter	28211|Alphaproteobacteria	S	EF hand	-	-	-	-	-	-	-	-	-	-	-	-	EF-hand_5
k141_4922_2	314232.SKA53_05568	3.24e-23	92.8	COG0440@1|root,COG0440@2|Bacteria,1RAGN@1224|Proteobacteria,2U5CW@28211|Alphaproteobacteria,2P8MT@245186|Loktanella	28211|Alphaproteobacteria	E	ACT domain	ilvH	-	2.2.1.6	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,ACT_5,ALS_ss_C
k141_2461_1	187272.Mlg_2412	2.94e-40	145.0	COG1838@1|root,COG1951@1|root,COG1838@2|Bacteria,COG1951@2|Bacteria,1MUV9@1224|Proteobacteria,1RN8U@1236|Gammaproteobacteria,1WWUB@135613|Chromatiales	135613|Chromatiales	C	Catalyzes the reversible hydration of fumarate to (S)- malate	-	-	4.2.1.2	ko:K01676	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumerase,Fumerase_C
k141_8587_1	1229909.NSED_01945	6.47e-114	338.0	COG5253@1|root,arCOG04169@2157|Archaea,41S9X@651137|Thaumarchaeota	651137|Thaumarchaeota	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	-	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	Plug_translocon,SecY
k141_7948_1	991905.SL003B_2882	7.25e-48	169.0	COG0747@1|root,COG0747@2|Bacteria,1MUZH@1224|Proteobacteria,2TU1J@28211|Alphaproteobacteria,4BQCE@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	E	Bacterial extracellular solute-binding proteins, family 5 Middle	gsiB	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
k141_7383_1	1096769.Pelub83DRAFT_0415	3.64e-32	112.0	2FDFA@1|root,345GY@2|Bacteria,1P1RR@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_9187_1	1131269.AQVV01000022_gene2245	1.57e-45	162.0	COG0815@1|root,COG0815@2|Bacteria	2|Bacteria	M	Transfers the fatty acyl group on membrane lipoproteins	lnt	-	-	ko:K03820	-	-	-	-	ko00000,ko01000	-	GT2	-	CN_hydrolase
k141_1214_1	402626.Rpic_3514	1.33e-80	254.0	COG0056@1|root,COG0056@2|Bacteria,1MUG7@1224|Proteobacteria,2VHQU@28216|Betaproteobacteria,1K1JD@119060|Burkholderiaceae	28216|Betaproteobacteria	F	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
k141_6775_1	1366046.HIMB11_01703	2.77e-50	178.0	COG0404@1|root,COG0665@1|root,COG0404@2|Bacteria,COG0665@2|Bacteria,1MUXJ@1224|Proteobacteria,2TRGS@28211|Alphaproteobacteria,3ZH34@58840|unclassified Rhodobacteraceae	28211|Alphaproteobacteria	E	Belongs to the GcvT family	dmgdh4	-	1.5.8.4	ko:K00315	ko00260,ko01100,map00260,map01100	-	R01565	RC00181	ko00000,ko00001,ko01000	-	-	-	DAO,FAO_M,GCV_T,GCV_T_C
k141_7949_1	717785.HYPMC_0791	8.75e-24	96.7	COG3665@1|root,COG3665@2|Bacteria,1N9DM@1224|Proteobacteria,2V8BH@28211|Alphaproteobacteria,3N8WU@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	S	Domain of unknown function (DUF1989)	-	-	-	ko:K09967	-	-	-	-	ko00000	-	-	-	DUF1989
k141_26_1	292415.Tbd_0655	2.16e-125	364.0	COG1071@1|root,COG1071@2|Bacteria,1MU5R@1224|Proteobacteria,2VIIQ@28216|Betaproteobacteria	28216|Betaproteobacteria	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	pdhA	-	1.2.4.1	ko:K00161,ko:K21416	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh
k141_6191_1	1415778.JQMM01000001_gene1253	2.45e-90	287.0	COG1067@1|root,COG1067@2|Bacteria,1MWGB@1224|Proteobacteria,1RMPC@1236|Gammaproteobacteria,1J4HR@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	O	Belongs to the peptidase S16 family	ycbZ	-	-	ko:K04770	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	AAA_32,Lon_C
k141_1262_1	391615.ABSJ01000039_gene1845	3.42e-46	156.0	COG0357@1|root,COG0357@2|Bacteria,1MY0K@1224|Proteobacteria,1RMRZ@1236|Gammaproteobacteria,1J6CC@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	Specifically methylates the N7 position of guanine in position 527 of 16S rRNA	rsmG	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.170	ko:K03501	-	-	-	-	ko00000,ko01000,ko03009,ko03036	-	-	-	GidB
k141_4347_1	1161935.H9D1G9_9CAUD	1.14e-08	60.1	4QAIV@10239|Viruses,4QYFZ@35237|dsDNA viruses  no RNA stage,4QSMH@28883|Caudovirales,4QNFF@10744|Podoviridae	10744|Podoviridae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_7419_2	159749.E7BWI5	7.24e-45	145.0	COG0636@1|root,KOG0232@2759|Eukaryota,2XGQC@2836|Bacillariophyta	2836|Bacillariophyta	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpH	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
k141_3727_1	1123401.JHYQ01000015_gene1409	1.43e-120	355.0	COG1850@1|root,COG1850@2|Bacteria,1MWEB@1224|Proteobacteria,1RRMX@1236|Gammaproteobacteria,4604Y@72273|Thiotrichales	72273|Thiotrichales	G	RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site	cbbL	-	4.1.1.39	ko:K01601	ko00630,ko00710,ko01100,ko01120,ko01200,map00630,map00710,map01100,map01120,map01200	M00165,M00166,M00532	R00024,R03140	RC00172,RC00859	ko00000,ko00001,ko00002,ko01000	-	-	-	RuBisCO_large,RuBisCO_large_N
k141_3112_1	1168065.DOK_01059	3.08e-66	213.0	COG4974@1|root,COG4974@2|Bacteria,1MVAN@1224|Proteobacteria,1RMSS@1236|Gammaproteobacteria,1J5GB@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	L	Phage integrase family	int	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
k141_6813_1	1121921.KB898708_gene1592	1e-85	265.0	COG1219@1|root,COG1219@2|Bacteria,1MVQK@1224|Proteobacteria,1RN9N@1236|Gammaproteobacteria,2PN7X@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	O	ClpX C4-type zinc finger	clpX	GO:0000166,GO:0000502,GO:0002020,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009376,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0019899,GO:0019904,GO:0030163,GO:0030164,GO:0030554,GO:0031597,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043335,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051301,GO:0051704,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0097718,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1904949,GO:1905368,GO:1905369	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
k141_3728_1	290512.Paes_0086	7.8e-12	65.9	COG3344@1|root,COG3344@2|Bacteria,1FECV@1090|Chlorobi	1090|Chlorobi	L	PFAM RNA-directed DNA polymerase (Reverse transcriptase)	-	-	2.7.7.49	ko:K00986	-	-	-	-	ko00000,ko01000	-	-	-	RVT_1
k141_28_1	395493.BegalDRAFT_3412	1.32e-106	326.0	COG2414@1|root,COG2414@2|Bacteria,1MWBB@1224|Proteobacteria,1RSCT@1236|Gammaproteobacteria,4624S@72273|Thiotrichales	72273|Thiotrichales	C	Aldehyde ferredoxin oxidoreductase, N-terminal domain	-	-	1.2.7.5	ko:K03738	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00309	R08571	RC00242	ko00000,ko00001,ko00002,ko01000	-	-	-	AFOR_C,AFOR_N
k141_5578_1	1123399.AQVE01000030_gene1363	4.52e-101	306.0	COG0064@1|root,COG0064@2|Bacteria,1MUKG@1224|Proteobacteria,1RP7U@1236|Gammaproteobacteria,45ZYW@72273|Thiotrichales	72273|Thiotrichales	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	-	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
k141_6193_1	502025.Hoch_1346	4.04e-16	78.6	COG3576@1|root,COG3576@2|Bacteria,1NBWC@1224|Proteobacteria,42X9X@68525|delta/epsilon subdivisions,2X3AH@28221|Deltaproteobacteria,2YV4Q@29|Myxococcales	28221|Deltaproteobacteria	S	Pfam:Pyridox_oxidase	-	-	-	ko:K07006	-	-	-	-	ko00000	-	-	-	Putative_PNPOx
k141_2500_1	1283300.ATXB01000001_gene2403	2.98e-60	201.0	COG0433@1|root,COG0433@2|Bacteria,1MUSH@1224|Proteobacteria,1RXZ7@1236|Gammaproteobacteria,1XE3M@135618|Methylococcales	135618|Methylococcales	S	AAA-like domain	-	-	-	ko:K06915	-	-	-	-	ko00000	-	-	-	DUF853,DUF87
k141_645_1	2850.Phatr49710	3.8e-22	100.0	KOG4428@1|root,KOG4428@2759|Eukaryota,2XFBN@2836|Bacillariophyta	2836|Bacillariophyta	T	phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_1880_1	391593.RCCS2_09014	2.91e-36	137.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2TQQ9@28211|Alphaproteobacteria,2P283@2433|Roseobacter	28211|Alphaproteobacteria	T	Sensory box histidine kinase response regulator	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,PAS_4,PAS_7,Response_reg
k141_1880_2	391593.RCCS2_09009	1.87e-39	136.0	COG0745@1|root,COG0745@2|Bacteria,1MWER@1224|Proteobacteria,2TUCU@28211|Alphaproteobacteria,2P2P2@2433|Roseobacter	28211|Alphaproteobacteria	K	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
k141_6815_1	472759.Nhal_0595	1.86e-99	307.0	COG1217@1|root,COG1217@2|Bacteria,1MV5Q@1224|Proteobacteria,1RMJB@1236|Gammaproteobacteria,1WW7K@135613|Chromatiales	135613|Chromatiales	T	GTP-binding protein TypA	-	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2
k141_5580_1	545264.KB898750_gene207	1e-82	267.0	COG0466@1|root,COG0466@2|Bacteria,1MUV2@1224|Proteobacteria,1RPCB@1236|Gammaproteobacteria,1WWYF@135613|Chromatiales	135613|Chromatiales	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
k141_6194_1	1249627.D779_0842	8.98e-51	174.0	COG0635@1|root,COG0635@2|Bacteria,1MU76@1224|Proteobacteria,1RN6I@1236|Gammaproteobacteria,1WW8U@135613|Chromatiales	135613|Chromatiales	H	Involved in the biosynthesis of porphyrin-containing compound	-	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
k141_9278_1	411459.RUMOBE_04123	1.34e-06	47.4	2EU6P@1|root,33MP7@2|Bacteria,1VM14@1239|Firmicutes,24U4C@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_8036_1	159749.E7BWL6	2.65e-91	285.0	COG0443@1|root,KOG0102@2759|Eukaryota,2XAKJ@2836|Bacillariophyta	2759|Eukaryota	O	heat shock	dnaK	GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005739,GO:0006605,GO:0006810,GO:0006886,GO:0006950,GO:0008104,GO:0008144,GO:0008150,GO:0009266,GO:0009408,GO:0009409,GO:0009507,GO:0009526,GO:0009532,GO:0009536,GO:0009570,GO:0009579,GO:0009628,GO:0009941,GO:0010035,GO:0010038,GO:0015031,GO:0015833,GO:0017076,GO:0030554,GO:0031967,GO:0031975,GO:0032553,GO:0032555,GO:0032559,GO:0033036,GO:0033365,GO:0034613,GO:0035639,GO:0036094,GO:0042221,GO:0042886,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0045036,GO:0045184,GO:0046686,GO:0046907,GO:0048046,GO:0050896,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0070727,GO:0071702,GO:0071705,GO:0072594,GO:0072596,GO:0072598,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	ko:K03283	ko03040,ko04010,ko04141,ko04144,ko04213,ko04612,ko04915,ko05134,ko05145,ko05162,ko05164,ko05169,map03040,map04010,map04141,map04144,map04213,map04612,map04915,map05134,map05145,map05162,map05164,map05169	M00353,M00355	-	-	ko00000,ko00001,ko00002,ko01009,ko03009,ko03029,ko03041,ko03051,ko03110,ko04131,ko04147,ko04516	1.A.33.1	-	-	HSP70
k141_6816_1	754477.Q7C_1336	9.44e-63	196.0	COG0127@1|root,COG0127@2|Bacteria,1MUK5@1224|Proteobacteria,1S27C@1236|Gammaproteobacteria,460I5@72273|Thiotrichales	72273|Thiotrichales	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions	rdgB	-	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	Ham1p_like
k141_6816_2	75379.Tint_2671	4.51e-18	82.8	COG0635@1|root,COG0635@2|Bacteria,1MU76@1224|Proteobacteria,2VHBB@28216|Betaproteobacteria,1KKAT@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Involved in the biosynthesis of porphyrin-containing compound	hemN2	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
k141_4966_1	525897.Dbac_3177	9.63e-53	172.0	28I53@1|root,2Z88I@2|Bacteria,1NE5N@1224|Proteobacteria,42QRB@68525|delta/epsilon subdivisions,2WMSD@28221|Deltaproteobacteria,2MEW9@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF3750)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3750
k141_8654_1	1304275.C41B8_10985	7.44e-41	140.0	COG0817@1|root,COG0817@2|Bacteria,1MUJI@1224|Proteobacteria,1RQPJ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group	ruvC	GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576	3.1.22.4	ko:K01159	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvC
k141_8654_2	1112274.KI911560_gene836	3.27e-15	72.4	COG0632@1|root,COG0632@2|Bacteria,1MWJR@1224|Proteobacteria,2VJ98@28216|Betaproteobacteria,2KM9H@206350|Nitrosomonadales	206350|Nitrosomonadales	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB	ruvA	-	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_C,RuvA_N
k141_2501_1	986075.CathTA2_0066	6.31e-25	95.9	arCOG05874@1|root,2ZJ01@2|Bacteria,1V450@1239|Firmicutes,4HFPA@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_1882_1	436308.Nmar_1398	1.91e-27	110.0	COG3593@1|root,arCOG03235@2157|Archaea,41SZV@651137|Thaumarchaeota	651137|Thaumarchaeota	L	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_15
k141_1882_2	1229909.NSED_07585	2.25e-87	277.0	arCOG08705@1|root,arCOG08705@2157|Archaea,41SXV@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_6818_1	1122603.ATVI01000010_gene988	3.75e-07	57.0	COG0515@1|root,COG3710@1|root,COG0515@2|Bacteria,COG3710@2|Bacteria,1NI1Y@1224|Proteobacteria,1S2FD@1236|Gammaproteobacteria,1X4HE@135614|Xanthomonadales	135614|Xanthomonadales	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,TPR_10,TPR_12,TPR_8,Trans_reg_C
k141_4968_1	159749.E7BWK6	2.87e-67	217.0	COG0464@1|root,KOG0730@2759|Eukaryota	2759|Eukaryota	O	ATP binding	ycf46	-	-	-	-	-	-	-	-	-	-	-	AAA
k141_1269_1	367336.OM2255_07970	6.43e-57	197.0	COG0086@1|root,COG0086@2|Bacteria,1MU3M@1224|Proteobacteria,2TRHV@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03046,ko:K13797	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
k141_7423_1	1307759.JOMJ01000001_gene2382	4.78e-82	255.0	COG4134@1|root,COG4134@2|Bacteria,1MWJ7@1224|Proteobacteria,42PFD@68525|delta/epsilon subdivisions,2WKQG@28221|Deltaproteobacteria,2M9UX@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Bacterial extracellular solute-binding protein	-	-	-	ko:K02055,ko:K05777	ko02024,map02024	M00192,M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11	-	-	SBP_bac_8
k141_1883_1	1122218.KB893654_gene2273	4.13e-73	243.0	COG0653@1|root,COG0653@2|Bacteria,1MUJZ@1224|Proteobacteria,2TTBF@28211|Alphaproteobacteria,1JTJZ@119045|Methylobacteriaceae	28211|Alphaproteobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	GO:0000166,GO:0002790,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015627,GO:0015628,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032940,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:0098776,GO:1901265,GO:1901363,GO:1904680	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
k141_6197_1	477228.YO5_11035	8.21e-48	167.0	COG2850@1|root,COG2850@2|Bacteria,1MW30@1224|Proteobacteria,1RN2Q@1236|Gammaproteobacteria,1Z0Y6@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	S	A domain family that is part of the cupin metalloenzyme superfamily.	ycfD	GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0009987,GO:0016491,GO:0016705,GO:0016706,GO:0018193,GO:0018195,GO:0019538,GO:0030961,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043687,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0046872,GO:0046914,GO:0051213,GO:0055114,GO:0071704,GO:1901564	1.14.11.47	ko:K18850	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Cupin_4
k141_8038_1	1123269.NX02_11135	1.36e-72	222.0	COG0521@1|root,COG0521@2|Bacteria,1R9W2@1224|Proteobacteria,2TTA8@28211|Alphaproteobacteria,2K0DJ@204457|Sphingomonadales	204457|Sphingomonadales	H	May be involved in the biosynthesis of molybdopterin	moaB	-	2.7.7.75	ko:K03638	ko00790,ko01100,map00790,map01100	-	R09726	RC00002	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth
k141_3118_1	1123355.JHYO01000025_gene2102	2.69e-100	307.0	COG1866@1|root,COG1866@2|Bacteria,1MWXN@1224|Proteobacteria,2TRC4@28211|Alphaproteobacteria,36XGE@31993|Methylocystaceae	28211|Alphaproteobacteria	C	Phosphoenolpyruvate carboxykinase	pckA	GO:0003674,GO:0003824,GO:0004611,GO:0004612,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0008150,GO:0008152,GO:0009058,GO:0016051,GO:0016829,GO:0016830,GO:0016831,GO:0019318,GO:0019319,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0071704,GO:1901576	4.1.1.49	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00170	R00341	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPCK_ATP
k141_1270_1	526225.Gobs_1101	0.00034	48.5	COG4733@1|root,COG4733@2|Bacteria,2HH13@201174|Actinobacteria,4EW6W@85013|Frankiales	201174|Actinobacteria	S	Fibronectin type 3 domain	-	-	-	-	-	-	-	-	-	-	-	-	fn3
k141_1884_1	1535422.ND16A_0740	2.74e-144	419.0	COG3119@1|root,COG3119@2|Bacteria,1MUJH@1224|Proteobacteria,1RN2V@1236|Gammaproteobacteria,2Q7EB@267889|Colwelliaceae	1236|Gammaproteobacteria	P	PFAM sulfatase	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
k141_2502_3	1116472.MGMO_69c00070	1.74e-11	63.9	COG1961@1|root,COG1961@2|Bacteria,1R3XB@1224|Proteobacteria	1224|Proteobacteria	L	Resolvase	tnpR	-	-	ko:K14060	-	-	-	-	ko00000	-	-	-	HTH_7,Resolvase
k141_1272_1	1449049.JONW01000003_gene2105	1.86e-05	46.2	COG4630@1|root,COG4630@2|Bacteria,1MWI1@1224|Proteobacteria,2TR3Q@28211|Alphaproteobacteria,2KIGC@204458|Caulobacterales	204458|Caulobacterales	F	TIGRFAM xanthine dehydrogenase, small subunit	-	-	1.17.1.4	ko:K13481	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103	RC00143	ko00000,ko00001,ko00002,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5,Fer2,Fer2_2
k141_1272_2	1487953.JMKF01000035_gene1186	4.05e-47	154.0	COG2351@1|root,COG2351@2|Bacteria,1G806@1117|Cyanobacteria,1HBWH@1150|Oscillatoriales	1117|Cyanobacteria	S	Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily	-	-	3.5.2.17	ko:K07127	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R06601	RC03393	ko00000,ko00001,ko00002,ko01000,ko02000	9.B.35.1.2,9.B.35.2	-	-	Transthyretin
k141_36_1	2340.JV46_15490	8.03e-71	215.0	COG2923@1|root,COG2923@2|Bacteria,1N8RV@1224|Proteobacteria,1SD0S@1236|Gammaproteobacteria,1J7BW@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	P	Belongs to the DsrF TusC family	tusC	GO:0002097,GO:0002098,GO:0002143,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1902494,GO:1990228,GO:1990234	-	ko:K07236	ko04122,map04122	-	-	-	ko00000,ko00001,ko03016	-	-	-	DrsE
k141_6200_1	247633.GP2143_12566	3.76e-18	88.6	COG1198@1|root,COG1198@2|Bacteria,1MUUZ@1224|Proteobacteria,1RPZ7@1236|Gammaproteobacteria,1J4R4@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006276,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010212,GO:0010332,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042221,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0046677,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,ResIII
k141_9284_1	545264.KB898747_gene433	3.25e-40	152.0	COG0591@1|root,COG4191@1|root,COG0591@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,1T44V@1236|Gammaproteobacteria,1WWXN@135613|Chromatiales	135613|Chromatiales	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_4
k141_3734_1	546266.NEIMUCOT_05882	2.81e-13	67.4	COG1762@1|root,COG1762@2|Bacteria,1RD0E@1224|Proteobacteria,2VRDH@28216|Betaproteobacteria,2KR2M@206351|Neisseriales	206351|Neisseriales	G	PTS IIA-like nitrogen-regulatory protein PtsN	ptsN	-	-	ko:K02806	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	-	-	-	PTS_EIIA_2
k141_3734_2	765914.ThisiDRAFT_0195	1.22e-53	179.0	COG1660@1|root,COG1660@2|Bacteria,1MVX6@1224|Proteobacteria,1RNJX@1236|Gammaproteobacteria,1WW9Z@135613|Chromatiales	135613|Chromatiales	S	Displays ATPase and GTPase activities	-	-	-	ko:K06958	-	-	-	-	ko00000,ko03019	-	-	-	ATP_bind_2
k141_4357_1	765913.ThidrDRAFT_3356	1.52e-107	338.0	COG0305@1|root,COG1372@1|root,COG0305@2|Bacteria,COG1372@2|Bacteria,1MUG9@1224|Proteobacteria,1RPM2@1236|Gammaproteobacteria,1WW1X@135613|Chromatiales	135613|Chromatiales	L	it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins	-	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C,Intein_splicing,LAGLIDADG_3
k141_6201_1	1198232.CYCME_2176	3.51e-83	262.0	COG0459@1|root,COG0459@2|Bacteria,1MURR@1224|Proteobacteria,1RMTB@1236|Gammaproteobacteria,4600M@72273|Thiotrichales	72273|Thiotrichales	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	-	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
k141_5585_1	644076.SCH4B_4719	1.48e-18	84.0	COG2253@1|root,COG2253@2|Bacteria,1MWST@1224|Proteobacteria,2TSSG@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Nucleotidyl transferase AbiEii toxin, Type IV TA system	-	-	-	-	-	-	-	-	-	-	-	-	AbiEii
k141_5585_2	1469245.JFBG01000047_gene2191	4.88e-52	171.0	COG5340@1|root,COG5340@2|Bacteria,1MY3Y@1224|Proteobacteria,1S00U@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	Transcriptional regulator, AbiEi antitoxin N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AbiEi_3,AbiEi_3_N
k141_8041_1	395493.BegalDRAFT_1394	6.12e-56	192.0	COG5265@1|root,COG5265@2|Bacteria,1NSKS@1224|Proteobacteria,1T1W9@1236|Gammaproteobacteria,46223@72273|Thiotrichales	72273|Thiotrichales	V	involved in Fe-S cluster assembly	-	-	-	-	-	-	-	-	-	-	-	-	ABC_membrane,ABC_tran
k141_6202_1	1461694.ATO9_01160	2.59e-67	217.0	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,2TQQ7@28211|Alphaproteobacteria,2PCC0@252301|Oceanicola	28211|Alphaproteobacteria	I	Belongs to the thiolase family	vraB	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
k141_3735_1	1131269.AQVV01000010_gene2470	3.31e-116	355.0	COG1048@1|root,COG1048@2|Bacteria	2|Bacteria	C	aconitate hydratase activity	acnA	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
k141_1888_1	1347368.HG964405_gene6101	1.98e-33	133.0	COG3391@1|root,COG4632@1|root,COG4733@1|root,COG3391@2|Bacteria,COG4632@2|Bacteria,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	tagL	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Flg_new,NAGPA,SLH
k141_6884_2	396588.Tgr7_2192	3.82e-60	200.0	COG0247@1|root,COG0247@2|Bacteria,1NZIG@1224|Proteobacteria,1RYPW@1236|Gammaproteobacteria,1WXQI@135613|Chromatiales	135613|Chromatiales	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_17,Fer4_8
k141_8713_1	1121943.KB899992_gene2227	3.41e-50	171.0	COG0216@1|root,COG0216@2|Bacteria,1MV28@1224|Proteobacteria,1RM7Q@1236|Gammaproteobacteria,1XHU3@135619|Oceanospirillales	135619|Oceanospirillales	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
k141_4426_1	272123.Anacy_2414	7.67e-29	104.0	2E88X@1|root,332MV@2|Bacteria,1G9GY@1117|Cyanobacteria,1HPBN@1161|Nostocales	1117|Cyanobacteria	S	One of the components of the core complex of photosystem II (PSII), required for its stability and or assembly. PSII is a light-driven water plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation. It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation	psbH	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0009521,GO:0009523,GO:0009579,GO:0016020,GO:0030075,GO:0030096,GO:0032991,GO:0034357,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044422,GO:0044424,GO:0044425,GO:0044436,GO:0044444,GO:0044459,GO:0044464,GO:0071944,GO:0098796,GO:0098797	-	ko:K02709	ko00195,ko01100,map00195,map01100	-	-	-	ko00000,ko00001,ko00194	-	-	iJN678.psbH	PsbH
k141_9357_2	666685.R2APBS1_2394	4.97e-49	164.0	COG0755@1|root,COG0755@2|Bacteria,1MU61@1224|Proteobacteria,1RP3R@1236|Gammaproteobacteria,1X357@135614|Xanthomonadales	135614|Xanthomonadales	O	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes	ccmC	-	-	ko:K02195	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	-	Cytochrom_C_asm
k141_724_1	99598.Cal7507_5569	3.16e-14	69.3	COG1396@1|root,COG1396@2|Bacteria,1G7Q5@1117|Cyanobacteria	1117|Cyanobacteria	K	PFAM Helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
k141_724_2	118161.KB235918_gene77	3.19e-47	154.0	COG4679@1|root,COG4679@2|Bacteria,1G6N5@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM Phage derived protein Gp49-like (DUF891)	-	-	-	-	-	-	-	-	-	-	-	-	Gp49
k141_6275_1	1197477.IA57_10865	5.16e-47	162.0	COG1538@1|root,COG1538@2|Bacteria,4NDXW@976|Bacteroidetes,1HXSD@117743|Flavobacteriia	976|Bacteroidetes	MU	PFAM Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
k141_6275_2	1296416.JACB01000001_gene3337	2.02e-40	149.0	COG3696@1|root,COG3696@2|Bacteria,4P36A@976|Bacteroidetes,1IJ7V@117743|Flavobacteriia,2YIRB@290174|Aquimarina	976|Bacteroidetes	P	AcrB/AcrD/AcrF family	-	-	-	ko:K07787,ko:K15726	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.2,2.A.6.1.4	-	-	ACR_tran
k141_4429_1	349102.Rsph17025_1682	0.000293	42.4	COG1175@1|root,COG1175@2|Bacteria,1MVF1@1224|Proteobacteria,2TST1@28211|Alphaproteobacteria,1FB63@1060|Rhodobacter	28211|Alphaproteobacteria	P	PFAM binding-protein-dependent transport systems inner membrane component	smoF	-	-	ko:K10228	ko02010,map02010	M00200	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.5	-	-	BPD_transp_1
k141_4429_2	311402.Avi_3567	1.34e-49	169.0	COG1653@1|root,COG1653@2|Bacteria,1MUNZ@1224|Proteobacteria,2TSYG@28211|Alphaproteobacteria,4B72C@82115|Rhizobiaceae	28211|Alphaproteobacteria	G	ABC transporter substrate-binding protein	smoE	-	-	ko:K02027,ko:K10227	ko02010,map02010	M00200,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.5	-	-	SBP_bac_1
k141_2575_1	666685.R2APBS1_1243	7.27e-13	70.9	COG4970@1|root,COG4970@2|Bacteria,1NGHS@1224|Proteobacteria,1SGGC@1236|Gammaproteobacteria,1X7JS@135614|Xanthomonadales	135614|Xanthomonadales	NU	Type II transport protein GspH	-	-	-	ko:K08084	-	-	-	-	ko00000,ko02044	3.A.15.2	-	-	GspH,N_methyl
k141_8115_1	1122918.KB907252_gene2941	2.88e-36	135.0	COG3239@1|root,COG3239@2|Bacteria,1TP3B@1239|Firmicutes,4H9TS@91061|Bacilli,26RAC@186822|Paenibacillaceae	91061|Bacilli	I	Fatty acid desaturase	des	-	1.14.19.23,1.14.19.45	ko:K10255	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase
k141_8732_1	269796.Rru_A2432	6.89e-47	163.0	COG2022@1|root,COG2022@2|Bacteria,1N0N5@1224|Proteobacteria,2TSXS@28211|Alphaproteobacteria,2JPMG@204441|Rhodospirillales	204441|Rhodospirillales	H	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S	thiG	-	2.8.1.10	ko:K03149	ko00730,ko01100,map00730,map01100	-	R10247	RC03096,RC03097,RC03461	ko00000,ko00001,ko01000	-	-	-	ThiG,ThiS
k141_6293_1	485913.Krac_3352	1.38e-24	107.0	COG2909@1|root,COG2909@2|Bacteria,2G7WA@200795|Chloroflexi	200795|Chloroflexi	K	intracellular signal transduction	-	-	-	-	-	-	-	-	-	-	-	-	BTAD
k141_121_1	1116472.MGMO_50c00030	3.29e-75	244.0	COG0653@1|root,COG0653@2|Bacteria,1MUJZ@1224|Proteobacteria,1RM9M@1236|Gammaproteobacteria,1XDPU@135618|Methylococcales	1224|Proteobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	-	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	Helicase_C,SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
k141_742_1	1265503.KB905164_gene1823	2.34e-22	97.1	COG1806@1|root,COG1806@2|Bacteria,1MUHU@1224|Proteobacteria,1RPHX@1236|Gammaproteobacteria,2Q6FN@267889|Colwelliaceae	1236|Gammaproteobacteria	F	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation dephosphorylation	ydiA	GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0030234,GO:0044424,GO:0044444,GO:0044464,GO:0050790,GO:0065007,GO:0065009,GO:0098772	2.7.11.33,2.7.4.28	ko:K09773	-	-	-	-	ko00000,ko01000	-	-	-	Kinase-PPPase
k141_8116_1	768671.ThimaDRAFT_0873	1.55e-42	154.0	COG3653@1|root,COG3653@2|Bacteria,1MWWY@1224|Proteobacteria,1TFGB@1236|Gammaproteobacteria,1X1MI@135613|Chromatiales	135613|Chromatiales	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
k141_3201_1	435908.IDSA_11395	3.45e-54	184.0	COG0845@1|root,COG0845@2|Bacteria,1NQDN@1224|Proteobacteria,1RRFE@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
k141_5060_1	530564.Psta_4082	5.6e-40	153.0	COG3209@1|root,COG4932@1|root,COG3209@2|Bacteria,COG4932@2|Bacteria,2IYH3@203682|Planctomycetes	203682|Planctomycetes	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Dockerin_1,SdrD_B
k141_8733_1	1415778.JQMM01000001_gene554	6.39e-18	82.4	COG0445@1|root,COG0445@2|Bacteria,1MU6F@1224|Proteobacteria,1RMM1@1236|Gammaproteobacteria,1J4X7@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	D	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34	gidA	GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009451,GO:0009628,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0050896,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363	-	ko:K03495	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko03016,ko03036	-	-	-	GIDA,GIDA_assoc
k141_8733_2	1242864.D187_000932	2.68e-11	66.2	COG0596@1|root,COG0596@2|Bacteria,1R6KU@1224|Proteobacteria	1224|Proteobacteria	G	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4
k141_2043_1	644283.Micau_1274	2.68e-28	115.0	COG2203@1|root,COG2208@1|root,COG2203@2|Bacteria,COG2208@2|Bacteria,2GKEF@201174|Actinobacteria,4DGRE@85008|Micromonosporales	201174|Actinobacteria	T	Serine phosphatase RsbU, regulator of sigma subunit	-	-	-	-	-	-	-	-	-	-	-	-	GAF,SpoIIE
k141_2043_2	1192868.CAIU01000020_gene2783	1.66e-20	90.5	COG1001@1|root,COG1001@2|Bacteria,1MVFP@1224|Proteobacteria,2TR1X@28211|Alphaproteobacteria,43H7K@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	F	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family	-	-	3.5.4.2	ko:K01486	ko00230,ko01100,map00230,map01100	-	R01244	RC00477	ko00000,ko00001,ko01000	-	-	-	Adenine_deam_C,Amidohydro_1
k141_5127_1	909943.HIMB100_00004090	3.15e-79	250.0	COG3333@1|root,COG3333@2|Bacteria,1MUKR@1224|Proteobacteria,2TR4Q@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Protein conserved in bacteria	-	-	-	ko:K07793	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.80.1	-	-	TctA
k141_9443_1	589924.Ferp_1683	8.81e-59	197.0	COG0683@1|root,arCOG01020@2157|Archaea,2XVWV@28890|Euryarchaeota,245XV@183980|Archaeoglobi	183980|Archaeoglobi	E	Periplasmic binding protein domain	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
k141_3265_1	330214.NIDE3046	2.64e-59	206.0	COG0466@1|root,COG0466@2|Bacteria,3J0DQ@40117|Nitrospirae	40117|Nitrospirae	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	-	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
k141_7541_1	1381123.AYOD01000016_gene2643	1.83e-46	170.0	COG1178@1|root,COG1178@2|Bacteria,1MWCF@1224|Proteobacteria,2TQKC@28211|Alphaproteobacteria,43GPK@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	P	thiamine ABC transporter	thiP	-	-	ko:K02063	ko02010,map02010	M00191	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.19	-	-	BPD_transp_1
k141_2044_2	635013.TherJR_2634	5.1e-07	55.8	COG0845@1|root,COG0845@2|Bacteria,1TT2M@1239|Firmicutes,24BJV@186801|Clostridia,2676T@186807|Peptococcaceae	186801|Clostridia	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
k141_3885_1	2850.Phatr43299	2.03e-21	94.0	COG1132@1|root,KOG0054@2759|Eukaryota	2759|Eukaryota	V	ATPase activity, coupled to transmembrane movement of substances	MRPA	-	-	ko:K05666	ko01523,ko01524,ko02010,ko04976,map01523,map01524,map02010,map04976	-	-	-	ko00000,ko00001,ko02000	3.A.1.208.2	-	-	ABC_membrane,ABC_tran
k141_810_1	225937.HP15_759	4.11e-13	68.6	COG0806@1|root,COG0806@2|Bacteria,1MWQR@1224|Proteobacteria,1RNJ2@1236|Gammaproteobacteria,467CY@72275|Alteromonadaceae	1236|Gammaproteobacteria	J	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes	rimM	GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0022607,GO:0022613,GO:0022618,GO:0030490,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360	-	ko:K02860	-	-	-	-	ko00000,ko03009	-	-	-	PRC,RimM
k141_810_2	1385510.N781_12320	6.39e-21	90.5	COG0336@1|root,COG0336@2|Bacteria,1TPBV@1239|Firmicutes,4HBFV@91061|Bacilli,2Y9DJ@289201|Pontibacillus	91061|Bacilli	J	Belongs to the RNA methyltransferase TrmD family	trmD	GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	tRNA_m1G_MT
k141_9444_1	1229909.NSED_09350	1.12e-63	195.0	COG1594@1|root,arCOG00579@2157|Archaea,41SS3@651137|Thaumarchaeota	651137|Thaumarchaeota	K	Belongs to the archaeal rpoM eukaryotic RPA12 RPB9 RPC11 RNA polymerase family	-	-	-	ko:K03057	ko01100,map01100	-	-	-	br01611,ko00000,ko03021	-	-	-	TFIIS_C
k141_9444_2	1229909.NSED_09345	2.48e-09	56.6	COG0592@1|root,arCOG00488@2157|Archaea,41S6E@651137|Thaumarchaeota	651137|Thaumarchaeota	L	Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication	pcn	-	-	ko:K04802	ko03030,ko03410,ko03420,ko03430,ko04110,ko04530,ko05161,ko05166,map03030,map03410,map03420,map03430,map04110,map04530,map05161,map05166	M00295	-	-	ko00000,ko00001,ko00002,ko03032,ko03400	-	-	-	PCNA_C,PCNA_N
k141_6979_1	511051.CSE_07150	1.72e-34	135.0	COG0074@1|root,COG0074@2|Bacteria	2|Bacteria	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit	sucD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009361,GO:0032991,GO:0042709,GO:0044424,GO:0044444,GO:0044464,GO:0045239,GO:1902494	6.2.1.5	ko:K01902,ko:K02381	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_binding,Ligase_CoA
k141_2045_1	1122614.JHZF01000005_gene325	7.13e-134	400.0	COG3451@1|root,COG3451@2|Bacteria,1MXH0@1224|Proteobacteria,2TR1U@28211|Alphaproteobacteria,2PD49@252301|Oceanicola	28211|Alphaproteobacteria	U	Type IV secretion system protein B4	virB4	-	-	ko:K03199	ko03070,map03070	M00333	-	-	ko00000,ko00001,ko00002,ko02044	3.A.7	-	-	AAA_10,CagE_TrbE_VirB,TrwB_AAD_bind
k141_2663_1	159749.K0STS1	9.82e-49	177.0	COG2801@1|root,KOG0017@2759|Eukaryota,2XEDA@2836|Bacillariophyta	2836|Bacillariophyta	L	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	RVT_2
k141_7542_1	1234664.AMRO01000056_gene301	3.87e-40	136.0	arCOG05874@1|root,2ZJ01@2|Bacteria,1V450@1239|Firmicutes,4HFPA@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_4515_1	1121875.KB907551_gene1135	1.43e-41	145.0	COG0180@1|root,COG0180@2|Bacteria,4NETX@976|Bacteroidetes,1HY8G@117743|Flavobacteriia	976|Bacteroidetes	J	Belongs to the class-I aminoacyl-tRNA synthetase family	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
k141_1425_1	998674.ATTE01000001_gene642	2.88e-54	183.0	COG0141@1|root,COG0141@2|Bacteria,1MUUF@1224|Proteobacteria,1RMZD@1236|Gammaproteobacteria,460BB@72273|Thiotrichales	72273|Thiotrichales	E	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine	hisD	-	1.1.1.23	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01158,R01163,R03012	RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000	-	-	-	Histidinol_dh
k141_3268_1	391038.Bphy_7491	6.68e-57	198.0	COG2609@1|root,COG2609@2|Bacteria,1MV21@1224|Proteobacteria,2VHP1@28216|Betaproteobacteria,1K4GC@119060|Burkholderiaceae	28216|Betaproteobacteria	C	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	aceE1	GO:0000287,GO:0003674,GO:0003824,GO:0004738,GO:0005488,GO:0005515,GO:0008150,GO:0008152,GO:0016491,GO:0016903,GO:0019842,GO:0030976,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0046872,GO:0046983,GO:0048037,GO:0050662,GO:0055114,GO:0097159,GO:1901363,GO:1901681	1.2.4.1	ko:K00163	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_C,Transketolase_N
k141_6364_1	211586.SO_4533	1.79e-11	64.3	COG3335@1|root,COG3415@1|root,COG3335@2|Bacteria,COG3415@2|Bacteria,1RCFZ@1224|Proteobacteria,1S2QS@1236|Gammaproteobacteria,2QEEF@267890|Shewanellaceae	1236|Gammaproteobacteria	L	Winged helix-turn helix	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,HTH_32
k141_6364_2	1429916.X566_00575	8.01e-59	187.0	COG3415@1|root,COG3415@2|Bacteria,1RDMQ@1224|Proteobacteria,2U7PU@28211|Alphaproteobacteria,3K38Q@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	L	Winged helix-turn helix	-	-	-	-	-	-	-	-	-	-	-	-	HTH_29,HTH_32,HTH_33
k141_191_1	318161.Sden_3580	8.3e-14	69.7	COG2801@1|root,COG2801@2|Bacteria,1MZ45@1224|Proteobacteria,1RSNX@1236|Gammaproteobacteria,2QAE4@267890|Shewanellaceae	1236|Gammaproteobacteria	L	Winged helix-turn helix	ylbG	-	-	-	-	-	-	-	-	-	-	-	HTH_29,rve,rve_2,rve_3
k141_4517_1	1249634.D781_4340	4.82e-13	73.9	COG0642@1|root,COG2205@2|Bacteria,1MUAK@1224|Proteobacteria,1RPP2@1236|Gammaproteobacteria,401SD@613|Serratia	1236|Gammaproteobacteria	T	in high osmolarity EnvZ autophosphorylates itself and transfers phosphoryl group to OmpR	envZ	GO:0000155,GO:0000160,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0004721,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006468,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009898,GO:0009987,GO:0016020,GO:0016021,GO:0016301,GO:0016310,GO:0016311,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0016787,GO:0016788,GO:0016791,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0031224,GO:0031226,GO:0035556,GO:0036211,GO:0042578,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0046777,GO:0047484,GO:0048583,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0071704,GO:0071944,GO:0080134,GO:0098552,GO:0098562,GO:0140096,GO:1901564	2.7.13.3	ko:K07638	ko02020,ko02026,map02020,map02026	M00445,M00742,M00743	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
k141_6982_1	712898.Pvag_0191	6.04e-23	101.0	COG0001@1|root,COG0001@2|Bacteria,1MUY5@1224|Proteobacteria,1RM7N@1236|Gammaproteobacteria,3VXSM@53335|Pantoea	1236|Gammaproteobacteria	H	Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate during the porphyrin biosynthesis pathway	hemL	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016853,GO:0016866,GO:0016869,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042286,GO:0042440,GO:0042802,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0046501,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	iUMNK88_1353.UMNK88_158	Aminotran_3
k141_1427_1	998674.ATTE01000001_gene3921	3.33e-55	189.0	COG3333@1|root,COG3333@2|Bacteria,1MUKR@1224|Proteobacteria,1RQPW@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	TctA
k141_2048_2	1379270.AUXF01000002_gene1761	9.48e-14	72.0	COG0477@1|root,COG2814@2|Bacteria,1ZT84@142182|Gemmatimonadetes	142182|Gemmatimonadetes	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
k141_5132_1	159749.E7BWC8	1.04e-28	109.0	COG0081@1|root,KOG1569@2759|Eukaryota,2XFIB@2836|Bacillariophyta	2836|Bacillariophyta	J	Binds directly to 23S rRNA. Might be involved in E site tRNA release	-	GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009507,GO:0009536,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	-	-	-	-	-	-	-	-	-	Ribosomal_L1
k141_5132_2	159749.E7BWC7	3.02e-85	252.0	COG0080@1|root,KOG3257@2759|Eukaryota	2759|Eukaryota	J	rRNA binding	rpl11	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009507,GO:0009526,GO:0009532,GO:0009536,GO:0009570,GO:0009941,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0031967,GO:0031975,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02863,ko:K02867	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L11,Ribosomal_L11_N
k141_4518_1	1396141.BATP01000003_gene5166	4.08e-96	299.0	COG0370@1|root,COG0370@2|Bacteria,46SH4@74201|Verrucomicrobia,2ITUZ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Ferrous iron transport protein B C terminus	-	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoB_C,FeoB_N,Gate
k141_9446_1	331869.BAL199_03119	1.5e-136	397.0	COG1804@1|root,COG1804@2|Bacteria,1MU2K@1224|Proteobacteria,2TR7Q@28211|Alphaproteobacteria,4BPJW@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	C	acyl-CoA transferases carnitine dehydratase	MA20_43260	-	2.8.3.16	ko:K07749	-	-	-	-	ko00000,ko01000	-	-	-	CoA_transf_3
k141_7545_1	1122135.KB893171_gene2153	1.3e-55	182.0	COG0510@1|root,COG0510@2|Bacteria,1N77Z@1224|Proteobacteria,2TRW6@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	Choline kinase	-	-	-	-	-	-	-	-	-	-	-	-	APH,Choline_kinase
k141_815_1	1381123.AYOD01000035_gene3567	4.36e-88	268.0	COG3367@1|root,COG3367@2|Bacteria,1MVEX@1224|Proteobacteria,2TS0Y@28211|Alphaproteobacteria,43IFA@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	Domain of unknown function (DUF1611_N) Rossmann-like domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF1611,DUF1611_N
k141_6367_1	156889.Mmc1_1104	9.77e-44	153.0	COG3000@1|root,COG3000@2|Bacteria,1MW5G@1224|Proteobacteria,2TU63@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	COG3000 Sterol desaturase	-	-	-	-	-	-	-	-	-	-	-	-	FA_hydroxylase
k141_5133_1	1121875.KB907561_gene523	8.81e-41	139.0	COG0607@1|root,COG0607@2|Bacteria	2|Bacteria	P	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
k141_5133_2	118005.AWNK01000015_gene1025	8.79e-06	47.8	COG0192@1|root,COG0192@2|Bacteria	2|Bacteria	H	methionine adenosyltransferase activity	metK	GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
k141_3891_1	1187851.A33M_0952	3.81e-54	184.0	COG0119@1|root,COG0119@2|Bacteria,1MUNQ@1224|Proteobacteria,2TSCJ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)	-	-	-	-	-	-	-	-	-	-	-	-	HMGL-like
k141_6368_1	756272.Plabr_3518	9.35e-27	110.0	COG0265@1|root,COG0823@1|root,COG2234@1|root,COG0265@2|Bacteria,COG0823@2|Bacteria,COG2234@2|Bacteria,2IX8E@203682|Planctomycetes	203682|Planctomycetes	O	PA domain	-	-	-	-	-	-	-	-	-	-	-	-	PA,PD40,PDZ_2,Peptidase_M28
k141_1429_1	1123247.AUIJ01000003_gene1940	5.29e-81	268.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1MU7B@1224|Proteobacteria,2TRHQ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	glutamate synthase	gltB	-	1.4.1.13,1.4.1.14,1.4.7.1	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	-	R00021,R00093,R00114,R00248,R10086	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
k141_8793_1	754477.Q7C_2511	7.11e-51	161.0	COG0776@1|root,COG0776@2|Bacteria,1MZ5B@1224|Proteobacteria,1S8VH@1236|Gammaproteobacteria,4617D@72273|Thiotrichales	72273|Thiotrichales	L	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions	hupB	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
k141_2050_1	983545.Glaag_2186	1.45e-57	192.0	COG1253@1|root,COG1253@2|Bacteria,1N0IQ@1224|Proteobacteria,1RY1D@1236|Gammaproteobacteria,46A5K@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Domain of unknown function DUF21	-	-	-	-	-	-	-	-	-	-	-	-	DUF21
k141_9448_1	1384054.N790_11550	9.78e-09	55.8	COG1846@1|root,COG1846@2|Bacteria,1N1CJ@1224|Proteobacteria,1SCUJ@1236|Gammaproteobacteria,1X6IP@135614|Xanthomonadales	135614|Xanthomonadales	K	MarR family transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	MarR_2
k141_9448_2	768066.HELO_1509	9.52e-31	116.0	COG3483@1|root,COG3483@2|Bacteria,1MW68@1224|Proteobacteria,1RXYM@1236|Gammaproteobacteria,1XMHQ@135619|Oceanospirillales	135619|Oceanospirillales	E	Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety	kynA	-	1.13.11.11	ko:K00453	ko00380,ko01100,map00380,map01100	M00038	R00678	RC00356	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_dioxygenase
k141_5134_2	1049564.TevJSym_ag01080	2.3e-45	152.0	COG2922@1|root,COG2922@2|Bacteria,1RD5F@1224|Proteobacteria,1S43X@1236|Gammaproteobacteria,1J6PQ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF494)	smg	-	-	ko:K03747	-	-	-	-	ko00000	-	-	-	DUF494
k141_6985_1	1163408.UU9_15532	5.76e-34	134.0	COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,1RMZ8@1236|Gammaproteobacteria,1X486@135614|Xanthomonadales	135614|Xanthomonadales	I	3-hydroxyacyl-coa dehydrogenase	fadJ	-	1.1.1.35,4.2.1.17,5.1.2.3	ko:K01782	ko00071,ko00280,ko00281,ko00310,ko00362,ko00380,ko00410,ko00640,ko00650,ko00903,ko00930,ko01040,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00071,map00280,map00281,map00310,map00362,map00380,map00410,map00640,map00650,map00903,map00930,map01040,map01100,map01110,map01120,map01130,map01200,map01212	M00032,M00087	R01975,R03026,R03045,R03276,R04137,R04170,R04203,R04204,R04224,R04737,R04738,R04739,R04740,R04741,R04744,R04745,R04746,R04748,R04749,R05066,R05305,R06411,R06412,R06941,R06942,R07935,R07951,R08093,R08094	RC00029,RC00099,RC00117,RC00241,RC00525,RC00831,RC00834,RC00896,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	3HCDH,3HCDH_N,ECH_1
k141_8182_1	1380380.JIAX01000008_gene1938	3.84e-24	102.0	COG1167@1|root,COG1167@2|Bacteria,1MVGT@1224|Proteobacteria,2TRK7@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs	-	-	-	ko:K00375	-	-	-	-	ko00000,ko03000	-	-	-	Aminotran_1_2,GntR
k141_817_1	316275.VSAL_I0639	2.2e-73	236.0	COG0511@1|root,COG5016@1|root,COG0511@2|Bacteria,COG5016@2|Bacteria,1QTTG@1224|Proteobacteria,1RNG6@1236|Gammaproteobacteria,1XT1B@135623|Vibrionales	135623|Vibrionales	CI	oxaloacetate	oadA	-	4.1.1.3	ko:K01571	ko00620,ko01100,map00620,map01100	-	R00217	RC00040	ko00000,ko00001,ko01000,ko02000	3.B.1.1.1	-	-	Biotin_lipoyl,HMGL-like,PYC_OADA
k141_5745_1	69328.PVLB_00340	3.35e-53	186.0	COG3203@1|root,COG3203@2|Bacteria,1MXEB@1224|Proteobacteria,1RPY8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Protein of unknown function (DUF1302)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1302
k141_4521_1	65672.G4T9D2	1.64e-14	79.3	COG2801@1|root,KOG0017@2759|Eukaryota,38DPC@33154|Opisthokonta,3NUZ7@4751|Fungi,3UY7N@5204|Basidiomycota,227R3@155619|Agaricomycetes,3H58M@355688|Agaricomycetes incertae sedis	4751|Fungi	L	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	RVT_2,gag_pre-integrs,rve
k141_8794_1	1229909.NSED_06095	1.33e-132	384.0	COG1980@1|root,arCOG04180@2157|Archaea,41S67@651137|Thaumarchaeota	651137|Thaumarchaeota	G	Catalyzes two subsequent steps in gluconeogenesis the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3-phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P)	fbp	-	3.1.3.11,4.1.2.13	ko:K01622	ko00010,ko00030,ko00051,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00003	R00762,R01068,R01070,R02568,R04780	RC00017,RC00438,RC00439	ko00000,ko00001,ko00002,ko01000	-	-	-	FBPase_3
k141_6370_1	391593.RCCS2_01728	6.51e-84	258.0	COG0834@1|root,COG1652@1|root,COG0834@2|Bacteria,COG1652@2|Bacteria,1RGJ7@1224|Proteobacteria,2U8HA@28211|Alphaproteobacteria,2P598@2433|Roseobacter	28211|Alphaproteobacteria	ET	protein containing LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	LysM,SBP_bac_3
k141_2052_1	391008.Smal_3808	8.84e-49	167.0	COG0382@1|root,COG0382@2|Bacteria,1MV4Q@1224|Proteobacteria,1RMZ1@1236|Gammaproteobacteria,1X3CT@135614|Xanthomonadales	135614|Xanthomonadales	H	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate	ubiA	-	2.5.1.39	ko:K03179	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R05000,R05615	RC00209,RC02895	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
k141_1431_1	338963.Pcar_3003	8.76e-42	157.0	COG1538@1|root,COG1538@2|Bacteria,1MYXE@1224|Proteobacteria,42TA7@68525|delta/epsilon subdivisions,2WR7T@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
k141_6371_1	1229909.NSED_00030	2.69e-120	369.0	COG1615@1|root,arCOG06128@2157|Archaea,41SCS@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Uncharacterised protein family (UPF0182)	-	-	-	ko:K09118	-	-	-	-	ko00000	-	-	-	UPF0182
k141_197_1	55529.AAC35681	3.95e-60	191.0	COG0457@1|root,KOG1124@2759|Eukaryota	2759|Eukaryota	O	cellular component assembly	FKBPL	GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006091,GO:0008150,GO:0008152,GO:0009314,GO:0009579,GO:0009628,GO:0009987,GO:0015979,GO:0016043,GO:0019684,GO:0022603,GO:0022607,GO:0031647,GO:0034622,GO:0043933,GO:0044085,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0045765,GO:0048564,GO:0050789,GO:0050793,GO:0050821,GO:0050896,GO:0051239,GO:0060688,GO:0065003,GO:0065007,GO:0065008,GO:0071840,GO:1901342,GO:1905330,GO:1905553,GO:2000026	-	ko:K20097	-	-	-	-	ko00000,ko03110	-	-	-	TPR_1,TPR_16,TPR_2
k141_5746_1	159749.E7BWC1	4.88e-95	279.0	28NRD@1|root,2QTZ8@2759|Eukaryota,2XFHA@2836|Bacillariophyta	2836|Bacillariophyta	O	Photosystem I reaction centre subunit III	-	-	-	ko:K02694	ko00195,ko01100,map00195,map01100	M00163	-	-	ko00000,ko00001,ko00002,ko00194	-	-	-	PSI_PsaF
k141_8795_1	1123366.TH3_08017	2.29e-133	396.0	COG4263@1|root,COG4263@2|Bacteria,1MVIH@1224|Proteobacteria,2TTB5@28211|Alphaproteobacteria,2JR4S@204441|Rhodospirillales	204441|Rhodospirillales	C	Nitrous-oxide reductase is part of a bacterial respiratory system which is activated under anaerobic conditions in the presence of nitrate or nitrous oxide	nosZ	-	1.7.2.4	ko:K00376	ko00910,ko01120,map00910,map01120	M00529	R02804	RC02861	ko00000,ko00001,ko00002,ko01000	-	-	-	Cupredoxin_1
k141_2053_2	1297570.MESS4_370116	7.47e-24	102.0	COG5598@1|root,COG5598@2|Bacteria,1MX73@1224|Proteobacteria,2TS1M@28211|Alphaproteobacteria,43R7W@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	H	Trimethylamine methyltransferase (MTTB)	-	-	-	-	-	-	-	-	-	-	-	-	MTTB
k141_3895_1	391589.RGAI101_553	3.84e-49	160.0	2B1WH@1|root,30C4Q@2|Bacteria,1R3E9@1224|Proteobacteria,2U7UN@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	MAPEG family	-	-	-	-	-	-	-	-	-	-	-	-	MAPEG
k141_231_1	756272.Plabr_2991	4.33e-82	255.0	COG0798@1|root,COG0798@2|Bacteria,2IY8H@203682|Planctomycetes	203682|Planctomycetes	P	COG0798 Arsenite efflux pump ACR3 and related	-	-	-	ko:K03325	-	-	-	-	ko00000,ko02000	2.A.59	-	-	SBF
k141_2088_1	266809.PM03_10305	9.6e-103	307.0	COG1960@1|root,COG1960@2|Bacteria,1MUK0@1224|Proteobacteria,2TSAC@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	acyl-CoA dehydrogenase	gcdH	-	1.3.8.6	ko:K00252	ko00071,ko00310,ko00362,ko00380,ko01100,ko01120,ko01130,map00071,map00310,map00362,map00380,map01100,map01120,map01130	M00032	R02487,R02488,R10074	RC00052,RC00156	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
k141_7022_1	1453501.JELR01000001_gene2902	4.22e-64	207.0	COG0150@1|root,COG0150@2|Bacteria,1MURG@1224|Proteobacteria,1RNZZ@1236|Gammaproteobacteria,4644R@72275|Alteromonadaceae	1236|Gammaproteobacteria	F	Phosphoribosylformylglycinamidine cyclo-ligase	purM	GO:0003674,GO:0003824,GO:0004641,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016882,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	iECSF_1327.ECSF_2340	AIRS,AIRS_C
k141_8217_1	398580.Dshi_0063	2.55e-29	112.0	COG0483@1|root,COG0483@2|Bacteria,1MV4W@1224|Proteobacteria,2TV4R@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	Inositol monophosphatase	suhB2	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
k141_8217_2	1402135.SUH3_10875	6.98e-44	154.0	COG0312@1|root,COG0312@2|Bacteria,1MUVW@1224|Proteobacteria,2TSAV@28211|Alphaproteobacteria,3ZVKN@60136|Sulfitobacter	28211|Alphaproteobacteria	S	Putative modulator of DNA gyrase	pmbA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564	-	ko:K03592	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
k141_1470_1	1229909.NSED_04515	3.97e-76	231.0	COG5491@1|root,arCOG00452@2157|Archaea,41T30@651137|Thaumarchaeota	651137|Thaumarchaeota	D	conserved protein implicated in secretion	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_4559_2	35128.Thapsdraft1439	3.3e-51	166.0	291AN@1|root,2ST4Q@2759|Eukaryota,2XG4M@2836|Bacillariophyta	2836|Bacillariophyta	S	Protein of unknown function (DUF1257)	ycf35	-	-	-	-	-	-	-	-	-	-	-	DUF1257
k141_856_1	1122176.KB903551_gene4251	3.82e-63	219.0	COG3696@1|root,COG3696@2|Bacteria,4P36A@976|Bacteroidetes,1IR8E@117747|Sphingobacteriia	976|Bacteroidetes	P	AcrB/AcrD/AcrF family	-	-	-	ko:K07787,ko:K15726	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.2,2.A.6.1.4	-	-	ACR_tran
k141_8834_1	666509.RCA23_c01640	2.17e-140	423.0	COG0243@1|root,COG0243@2|Bacteria,1P01N@1224|Proteobacteria,2U1PA@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	psrA	-	1.8.5.6	ko:K21307	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R11487	RC00168	ko00000,ko00001,ko01000	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
k141_9487_1	35128.Thapsdraft1327	1.78e-189	541.0	COG0305@1|root,2QRXQ@2759|Eukaryota,2XEMK@2836|Bacillariophyta	2836|Bacillariophyta	L	DnaB-like helicase N terminal domain	dnaB	-	-	-	-	-	-	-	-	-	-	-	DnaB,DnaB_C
k141_8218_1	1229909.NSED_01425	2.7e-104	317.0	COG1245@1|root,arCOG00187@2157|Archaea,41S8K@651137|Thaumarchaeota	651137|Thaumarchaeota	E	RNase L inhibitor, RLI	-	-	-	ko:K06174	-	-	-	-	ko00000,ko03009	-	-	-	ABC_tran,Fer4,RLI
k141_7023_1	384765.SIAM614_29256	1.11e-77	247.0	COG3004@1|root,COG3004@2|Bacteria,1MW15@1224|Proteobacteria,2TSI5@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons	nhaA	-	-	ko:K03313	-	-	-	-	ko00000,ko02000	2.A.33.1	-	-	Na_H_antiport_1,Thioredoxin_4
k141_6412_1	111781.Lepto7376_1831	6.04e-11	62.4	COG0300@1|root,COG0300@2|Bacteria,1GQM8@1117|Cyanobacteria,1HHZ1@1150|Oscillatoriales	1117|Cyanobacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
k141_6412_2	754436.JCM19237_4369	9.92e-30	113.0	COG4461@1|root,COG4461@2|Bacteria,1R6Q3@1224|Proteobacteria,1S2QD@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	LprI,MliC
k141_5784_2	35128.Thapsdraft1342	1.89e-32	118.0	28NVH@1|root,2QVFH@2759|Eukaryota,2XFNZ@2836|Bacillariophyta	2836|Bacillariophyta	C	Photosystem I reaction centre subunit XI	psaL	-	-	ko:K02699	ko00195,ko01100,map00195,map01100	-	-	-	ko00000,ko00001,ko00194	-	-	-	PsaL
k141_2707_1	1121033.AUCF01000028_gene345	9.87e-12	70.5	COG0457@1|root,COG0457@2|Bacteria,1MUZK@1224|Proteobacteria,2TS0U@28211|Alphaproteobacteria,2JPRT@204441|Rhodospirillales	204441|Rhodospirillales	M	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_9,TPR_1,TPR_11,TPR_16,TPR_2,TPR_4,TPR_8
k141_235_1	388401.RB2150_00452	1.07e-64	207.0	COG2084@1|root,COG2084@2|Bacteria,1PU4S@1224|Proteobacteria,2TT0X@28211|Alphaproteobacteria,3ZG3J@58840|unclassified Rhodobacteraceae	28211|Alphaproteobacteria	I	3-hydroxyisobutyrate dehydrogenase	-	-	1.1.1.31	ko:K00020	ko00280,ko01100,map00280,map01100	-	R05066	RC00099	ko00000,ko00001,ko01000	-	-	-	NAD_binding_11,NAD_binding_2
k141_8836_1	319225.Plut_0421	3.06e-40	148.0	COG0662@1|root,COG0836@1|root,COG0662@2|Bacteria,COG0836@2|Bacteria,1FEDY@1090|Chlorobi	1090|Chlorobi	M	Cupin 2, conserved barrel domain protein	-	-	2.7.7.13,5.3.1.8	ko:K16011	ko00051,ko00520,ko01100,ko01110,ko01130,ko02025,map00051,map00520,map01100,map01110,map01130,map02025	M00114,M00362	R00885,R01819	RC00002,RC00376	ko00000,ko00001,ko00002,ko01000	-	-	-	MannoseP_isomer,NTP_transferase
k141_2092_1	105559.Nwat_0845	3.36e-121	360.0	COG3119@1|root,COG3119@2|Bacteria,1MUJH@1224|Proteobacteria,1RN2V@1236|Gammaproteobacteria,1WVZV@135613|Chromatiales	135613|Chromatiales	P	PFAM Sulfatase	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase,Sulfatase_C
k141_5785_1	880073.Calab_0834	4.46e-17	87.8	COG3385@1|root,COG3385@2|Bacteria,2NRDU@2323|unclassified Bacteria	2|Bacteria	L	Transposase DDE domain group 1	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_4
k141_1473_1	1384056.N787_00810	1e-66	217.0	COG3039@1|root,COG3039@2|Bacteria,1MUVI@1224|Proteobacteria,1RQVT@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	COG3666 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_6,DUF772
k141_8220_1	95619.PM1_0217380	2.41e-94	290.0	COG0504@1|root,COG0504@2|Bacteria,1MUIT@1224|Proteobacteria,1RM92@1236|Gammaproteobacteria	1236|Gammaproteobacteria	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	GO:0003674,GO:0003824,GO:0003883,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006220,GO:0006221,GO:0006241,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009208,GO:0009209,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046036,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	iECO103_1326.ECO103_3323,iPC815.YPO3377	CTP_synth_N,GATase
k141_7026_1	570967.JMLV01000010_gene1137	1.4e-82	248.0	COG0094@1|root,COG0094@2|Bacteria,1MUU9@1224|Proteobacteria,2TQPF@28211|Alphaproteobacteria,2JRV3@204441|Rhodospirillales	204441|Rhodospirillales	J	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits	rplE	-	-	ko:K02931	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L5,Ribosomal_L5_C
k141_5177_1	999141.GME_10356	2.88e-113	339.0	COG0056@1|root,COG0056@2|Bacteria,1MUG7@1224|Proteobacteria,1RP4V@1236|Gammaproteobacteria,1XHRG@135619|Oceanospirillales	135619|Oceanospirillales	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
k141_3933_1	345073.VC395_2572	1.24e-35	125.0	COG0736@1|root,COG0736@2|Bacteria,1MZBF@1224|Proteobacteria,1S98P@1236|Gammaproteobacteria,1XXAM@135623|Vibrionales	135623|Vibrionales	I	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein	acpS	GO:0003674,GO:0003824,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008897,GO:0009058,GO:0016740,GO:0016772,GO:0016780,GO:0044238,GO:0071704,GO:1901576	2.7.8.7	ko:K00997	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	-	ACPS
k141_3933_2	1225184.ALXE01000026_gene1505	1.08e-10	61.2	COG0854@1|root,COG0854@2|Bacteria,1MU9W@1224|Proteobacteria,1RMS5@1236|Gammaproteobacteria,3VZF7@53335|Pantoea	1236|Gammaproteobacteria	H	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate	pdxJ	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042802,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	2.6.99.2	ko:K03474	ko00750,ko01100,map00750,map01100	M00124	R05838	RC01476	ko00000,ko00001,ko00002,ko01000	-	-	iAF1260.b2564,iB21_1397.B21_02422,iBWG_1329.BWG_2328,iEC55989_1330.EC55989_2852,iECBD_1354.ECBD_1117,iECB_1328.ECB_02458,iECDH10B_1368.ECDH10B_2732,iECDH1ME8569_1439.ECDH1ME8569_2491,iECD_1391.ECD_02458,iECH74115_1262.ECH74115_3800,iECIAI1_1343.ECIAI1_2675,iECO103_1326.ECO103_3142,iECO111_1330.ECO111_3290,iECO26_1355.ECO26_3611,iECSE_1348.ECSE_2852,iECSP_1301.ECSP_3509,iECW_1372.ECW_m2792,iECs_1301.ECs3430,iEKO11_1354.EKO11_1169,iEcDH1_1363.EcDH1_1104,iEcE24377_1341.EcE24377A_2850,iEcHS_1320.EcHS_A2719,iEcolC_1368.EcolC_1113,iG2583_1286.G2583_3145,iJO1366.b2564,iJR904.b2564,iWFL_1372.ECW_m2792,iY75_1357.Y75_RS13390	PdxJ
k141_3308_1	4533.OB0092G10050.1	8.29e-19	89.7	COG2801@1|root,KOG0017@2759|Eukaryota,37YYP@33090|Viridiplantae,3GQD7@35493|Streptophyta,3M3FD@4447|Liliopsida,3IKKZ@38820|Poales	35493|Streptophyta	L	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	RVT_2
k141_8838_1	1265313.HRUBRA_01563	1.72e-79	250.0	COG3547@1|root,COG3547@2|Bacteria,1QYJU@1224|Proteobacteria,1RN0A@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Transposase IS116 IS110 IS902	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k141_7027_1	1828.JOKB01000054_gene975	8.7e-14	77.8	COG0154@1|root,COG0154@2|Bacteria,2GUUU@201174|Actinobacteria,4FZ4G@85025|Nocardiaceae	201174|Actinobacteria	J	Amidase	amdA	-	3.5.1.4	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	-	R02540,R03096,R03180,R03909,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000	-	-	-	Amidase
k141_237_2	1149133.ppKF707_5246	1.17e-91	278.0	COG0181@1|root,COG0181@2|Bacteria,1MU56@1224|Proteobacteria,1RMQ8@1236|Gammaproteobacteria,1YCYZ@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	H	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps	hemC	GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018065,GO:0018130,GO:0018160,GO:0018193,GO:0018198,GO:0019438,GO:0019538,GO:0033013,GO:0033014,GO:0034641,GO:0036211,GO:0042168,GO:0042440,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.61	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084	RC02317	ko00000,ko00001,ko00002,ko01000	-	-	iEC55989_1330.EC55989_4275,iECH74115_1262.ECH74115_5243,iECIAI1_1343.ECIAI1_3991,iECO103_1326.ECO103_4362,iECO111_1330.ECO111_4628,iECO26_1355.ECO26_4784,iECSE_1348.ECSE_4086,iEKO11_1354.EKO11_4554,iPC815.YPO3849	Porphobil_deam,Porphobil_deamC
k141_7589_1	298386.PBPRA1402	2.91e-72	228.0	COG4663@1|root,COG4663@2|Bacteria,1MVMD@1224|Proteobacteria,1RNCK@1236|Gammaproteobacteria,1XV1B@135623|Vibrionales	135623|Vibrionales	Q	Part of the tripartite ATP-independent periplasmic (TRAP) transport system	-	-	-	-	-	-	-	-	-	-	-	-	DctP
k141_2094_1	1122135.KB893138_gene1123	6.67e-52	177.0	COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,2TQMJ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system	-	-	3.6.3.30	ko:K02010,ko:K02052	ko02010,ko02024,map02010,map02024	M00190,M00193	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.10,3.A.1.11	-	-	ABC_tran,TOBE_2
k141_9521_1	1123290.AUDQ01000011_gene1594	1.44e-07	58.2	COG2132@1|root,COG2132@2|Bacteria,1TQSU@1239|Firmicutes,4HDD6@91061|Bacilli,26DPQ@186818|Planococcaceae	91061|Bacilli	Q	Multicopper oxidase	cotA	GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0016679,GO:0016682,GO:0016722,GO:0052716,GO:0055114	1.16.3.3	ko:K06324	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3
k141_6444_1	2340.JV46_12860	2.86e-122	375.0	COG1049@1|root,COG1049@2|Bacteria,1MVCR@1224|Proteobacteria,1RNMC@1236|Gammaproteobacteria,1J58B@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Belongs to the aconitase IPM isomerase family	acnB	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0003994,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006081,GO:0006082,GO:0006091,GO:0006097,GO:0006099,GO:0006101,GO:0006417,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009056,GO:0009060,GO:0009062,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0010608,GO:0015980,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017001,GO:0017144,GO:0019222,GO:0019541,GO:0019543,GO:0019626,GO:0019629,GO:0019752,GO:0031323,GO:0031326,GO:0032268,GO:0032787,GO:0034248,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046395,GO:0046459,GO:0046487,GO:0047456,GO:0048037,GO:0050789,GO:0050794,GO:0051171,GO:0051246,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0060255,GO:0065007,GO:0071704,GO:0072329,GO:0072350,GO:0080090,GO:0097159,GO:1901363,GO:1901575,GO:2000112	4.2.1.3,4.2.1.99	ko:K01682	ko00020,ko00630,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173	R01324,R01325,R01900,R04425	RC00497,RC00498,RC00618,RC01153	br01601,ko00000,ko00001,ko00002,ko01000	-	-	iECIAI1_1343.ECIAI1_0116,iPC815.YPO3415	Aconitase,Aconitase_2_N,Aconitase_B_N
k141_6444_2	545276.KB898724_gene2048	5.4e-53	179.0	COG0372@1|root,COG0372@2|Bacteria,1MUKX@1224|Proteobacteria,1RNDK@1236|Gammaproteobacteria,1WWHU@135613|Chromatiales	135613|Chromatiales	C	Belongs to the citrate synthase family	gltA	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
k141_2740_1	1049564.TevJSym_bh00110	2.53e-06	50.8	COG2304@1|root,COG2304@2|Bacteria,1MXQ7@1224|Proteobacteria,1RMDX@1236|Gammaproteobacteria,1J577@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	protein containing a von Willebrand factor type A (vWA) domain	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA,VWA_2
k141_2740_2	1121377.KB906403_gene3028	2.76e-08	58.9	COG2304@1|root,COG2304@2|Bacteria,1WJG3@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	von Willebrand factor, type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	BatA,VWA_2
k141_8251_1	867900.Celly_1324	1.34e-126	366.0	COG0330@1|root,COG0330@2|Bacteria,4NEP5@976|Bacteroidetes,1HWKG@117743|Flavobacteriia,1F8BY@104264|Cellulophaga	976|Bacteroidetes	O	COGs COG0330 Membrane protease subunits stomatin prohibitin homologs	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
k141_890_1	867900.Celly_1250	2.57e-41	140.0	COG0328@1|root,COG3341@1|root,COG0328@2|Bacteria,COG3341@2|Bacteria,4NI01@976|Bacteroidetes,1HXD6@117743|Flavobacteriia	976|Bacteroidetes	L	double-stranded RNA RNA-DNA hybrid binding protein	rnhA	-	3.1.26.4	ko:K03469	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	Cauli_VI,RNase_H
k141_275_1	34506.g723	1.75e-58	202.0	COG0458@1|root,KOG0370@2759|Eukaryota,38CAC@33154|Opisthokonta,3B9FF@33208|Metazoa,3CS9A@33213|Bilateria,40G12@6231|Nematoda,1KYNR@119089|Chromadorea,40UXW@6236|Rhabditida	33208|Metazoa	F	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity	-	-	-	-	-	-	-	-	-	-	-	-	CPSase_L_D2,CPSase_L_D3,CPSase_sm_chain,DapB_C,DapB_N,GATase,MGS
k141_7056_1	349965.yinte0001_12080	4.33e-80	252.0	COG0031@1|root,COG3620@1|root,COG0031@2|Bacteria,COG3620@2|Bacteria,1MUBE@1224|Proteobacteria,1RN6J@1236|Gammaproteobacteria,41FTG@629|Yersinia	1236|Gammaproteobacteria	EK	Domain in cystathionine beta-synthase and other proteins.	cysK	-	2.5.1.47,4.2.1.22	ko:K01697,ko:K01738	ko00260,ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021,M00035,M00338	R00891,R00897,R01290,R03601,R04859,R04942	RC00020,RC00056,RC00069,RC00256,RC00489,RC01246,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	CBS,PALP
k141_8252_2	1040986.ATYO01000002_gene4419	2.38e-40	143.0	COG0006@1|root,COG0006@2|Bacteria,1MWUT@1224|Proteobacteria,2TT29@28211|Alphaproteobacteria,43GYW@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	E	Creatinase/Prolidase N-terminal domain	y4tM	-	3.4.13.9,3.5.4.44	ko:K01271,ko:K15783	ko00260,ko01100,map00260,map01100	-	R09800	RC02661	ko00000,ko00001,ko01000,ko01002	-	-	-	Creatinase_N,Peptidase_M24
k141_2130_1	754477.Q7C_2088	3.84e-72	222.0	COG3647@1|root,COG3647@2|Bacteria,1RGJN@1224|Proteobacteria	1224|Proteobacteria	S	Membrane	-	-	-	ko:K08984	-	-	-	-	ko00000	-	-	-	DUF2238
k141_891_1	1056820.KB900633_gene2074	3.83e-66	219.0	COG1080@1|root,COG1080@2|Bacteria,1MUT8@1224|Proteobacteria,1RN6R@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)	-	-	2.7.3.9	ko:K08483	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	8.A.7	-	-	PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C
k141_3972_1	1085623.GNIT_3064	1.43e-113	333.0	COG0418@1|root,COG0418@2|Bacteria,1MUYP@1224|Proteobacteria,1RNEN@1236|Gammaproteobacteria,4642S@72275|Alteromonadaceae	1236|Gammaproteobacteria	F	Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate	pyrC	GO:0003674,GO:0003824,GO:0004151,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0046872,GO:0046914,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	iSBO_1134.SBO_2002,iYL1228.KPN_01074	Amidohydro_1
k141_2743_1	1229909.NSED_09565	2.6e-100	295.0	COG4221@1|root,arCOG01265@2157|Archaea,41S66@651137|Thaumarchaeota	651137|Thaumarchaeota	I	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
k141_892_1	999549.KI421513_gene1478	2.88e-46	160.0	COG0517@1|root,COG0517@2|Bacteria,1MXI6@1224|Proteobacteria,2TS6X@28211|Alphaproteobacteria,2814J@191028|Leisingera	28211|Alphaproteobacteria	S	Putative transposase	-	-	-	-	-	-	-	-	-	-	-	-	Y2_Tnp,Zn_Tnp_IS91
k141_3974_1	1122614.JHZF01000011_gene933	7.85e-14	70.5	28HR5@1|root,2Z7YN@2|Bacteria,1QV7P@1224|Proteobacteria,2UH1A@28211|Alphaproteobacteria,2PE6K@252301|Oceanicola	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Phage_connect_1
k141_3974_2	1317124.DW2_03479	1.29e-15	73.2	COG5614@1|root,COG5614@2|Bacteria,1N0CB@1224|Proteobacteria,2UBY8@28211|Alphaproteobacteria,2XNJ3@285107|Thioclava	28211|Alphaproteobacteria	S	Phage head-tail joining protein	-	-	-	-	-	-	-	-	-	-	-	-	Phage_H_T_join
k141_1510_1	717774.Marme_0481	1.71e-24	97.4	2ANPA@1|root,31DNS@2|Bacteria,1RHTE@1224|Proteobacteria,1S78C@1236|Gammaproteobacteria,1XKP9@135619|Oceanospirillales	135619|Oceanospirillales	S	Protein of unknown function (DUF3833)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3833
k141_2132_1	1123274.KB899418_gene2365	2.87e-75	249.0	COG0460@1|root,COG0527@1|root,COG0460@2|Bacteria,COG0527@2|Bacteria,2J5C6@203691|Spirochaetes	203691|Spirochaetes	E	Amino acid kinase family	-	-	1.1.1.3,2.7.2.4	ko:K12524	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00017,M00018,M00526,M00527	R00480,R01773,R01775	RC00002,RC00043,RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT,ACT_7,Homoserine_dh,NAD_binding_3
k141_5825_1	498211.CJA_2001	1.35e-106	332.0	COG1049@1|root,COG1049@2|Bacteria,1MVCR@1224|Proteobacteria,1RNMC@1236|Gammaproteobacteria,1FG9J@10|Cellvibrio	1236|Gammaproteobacteria	C	Aconitate B N-terminal domain	acnB	-	4.2.1.3,4.2.1.99	ko:K01682	ko00020,ko00630,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173	R01324,R01325,R01900,R04425	RC00497,RC00498,RC00618,RC01153	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_2_N,Aconitase_B_N
k141_8255_1	521674.Plim_0176	3.83e-93	286.0	COG0055@1|root,COG0055@2|Bacteria,2IY7P@203682|Planctomycetes	203682|Planctomycetes	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
k141_8868_1	937777.Deipe_0633	3.77e-36	131.0	COG0039@1|root,COG0039@2|Bacteria,1WJHY@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	Catalyzes the reversible oxidation of malate to oxaloacetate	mdh	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006107,GO:0006108,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009060,GO:0009117,GO:0009987,GO:0015980,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0016999,GO:0017144,GO:0019362,GO:0019637,GO:0019674,GO:0019752,GO:0030060,GO:0034641,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0045333,GO:0046483,GO:0046496,GO:0051186,GO:0055086,GO:0055114,GO:0071704,GO:0072350,GO:0072524,GO:1901360,GO:1901564	1.1.1.37	ko:K00024	ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740	R00342,R07136	RC00031	ko00000,ko00001,ko00002,ko01000	-	-	-	Ldh_1_C,Ldh_1_N
k141_3975_1	1415756.JQMY01000005_gene97	5.1e-18	85.5	COG3547@1|root,COG3547@2|Bacteria,1MUER@1224|Proteobacteria,2TSGZ@28211|Alphaproteobacteria,2PFSQ@252301|Oceanicola	28211|Alphaproteobacteria	L	Transposase IS116/IS110/IS902 family	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k141_2133_4	1144672.F966_03383	8.33e-06	48.1	COG3772@1|root,COG3772@2|Bacteria,1MZJD@1224|Proteobacteria,1S99W@1236|Gammaproteobacteria,3NKTC@468|Moraxellaceae	1236|Gammaproteobacteria	G	Phage lysozyme	-	-	3.2.1.17	ko:K01185	-	-	-	-	ko00000,ko01000	-	-	-	Phage_lysozyme
k141_4601_1	1396141.BATP01000004_gene5882	4.3e-73	233.0	COG2059@1|root,COG2059@2|Bacteria,46V8S@74201|Verrucomicrobia,2IUYF@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Chromate transporter	-	-	-	-	-	-	-	-	-	-	-	-	Chromate_transp
k141_945_2	935565.JAEM01000001_gene288	1.03e-19	81.3	COG2963@1|root,COG2963@2|Bacteria,1N06K@1224|Proteobacteria,2U9BK@28211|Alphaproteobacteria,2PXQ7@265|Paracoccus	28211|Alphaproteobacteria	L	Transposase	-	-	-	ko:K07483	-	-	-	-	ko00000	-	-	-	HTH_Tnp_1
k141_5879_1	1089551.KE386572_gene956	1.49e-50	176.0	COG0154@1|root,COG0154@2|Bacteria,1MW3Z@1224|Proteobacteria,2TS56@28211|Alphaproteobacteria,4BQ88@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	J	Amidase	MA20_16525	-	3.5.1.4	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	-	R02540,R03096,R03180,R03909,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000	-	-	-	Amidase
k141_2189_1	1121931.AUHG01000012_gene2833	1.55e-46	159.0	COG0526@1|root,COG0526@2|Bacteria,4NNNN@976|Bacteroidetes,1I2HW@117743|Flavobacteriia	976|Bacteroidetes	CO	COG0526, thiol-disulfide isomerase and thioredoxins	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
k141_8911_1	35128.Thapsdraft2050	0.0	1583.0	COG0086@1|root,2RUNH@2759|Eukaryota,2XF5V@2836|Bacillariophyta	2836|Bacillariophyta	H	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC2	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009536,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464	-	-	-	-	-	-	-	-	-	-	RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
k141_334_1	1492922.GY26_07245	1.05e-15	79.7	COG0697@1|root,COG0697@2|Bacteria,1RBFV@1224|Proteobacteria,1S416@1236|Gammaproteobacteria,1JBIJ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
k141_5268_1	305700.B447_17236	1.62e-13	71.2	COG5569@1|root,COG5569@2|Bacteria,1N8CJ@1224|Proteobacteria,2VVSU@28216|Betaproteobacteria,2KX75@206389|Rhodocyclales	206389|Rhodocyclales	S	Copper binding periplasmic protein CusF	-	-	-	-	-	-	-	-	-	-	-	-	CusF_Ec
k141_9568_1	1134474.O59_002611	2.5e-76	235.0	COG0528@1|root,COG0528@2|Bacteria,1MV3N@1224|Proteobacteria,1RMHX@1236|Gammaproteobacteria,1FH1R@10|Cellvibrio	1236|Gammaproteobacteria	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	-	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
k141_4029_1	1120983.KB894572_gene3159	4.01e-39	144.0	COG3333@1|root,COG3333@2|Bacteria,1MUKR@1224|Proteobacteria,2TVI3@28211|Alphaproteobacteria,1JN67@119043|Rhodobiaceae	28211|Alphaproteobacteria	S	Tripartite tricarboxylate transporter TctA family	-	-	-	-	-	-	-	-	-	-	-	-	TctA
k141_2190_1	1298863.AUEP01000019_gene3529	3.17e-67	212.0	COG0500@1|root,COG2226@2|Bacteria,2GJSF@201174|Actinobacteria,4DT5X@85009|Propionibacteriales	201174|Actinobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
k141_1567_1	35128.Thapsdraft1378	1.95e-144	410.0	COG0356@1|root,KOG4665@2759|Eukaryota,2XF1K@2836|Bacillariophyta	2836|Bacillariophyta	P	it plays a direct role in the translocation of protons across the membrane	atpI	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
k141_9569_1	1232683.ADIMK_0873	1.18e-82	254.0	COG0057@1|root,COG0057@2|Bacteria,1MU93@1224|Proteobacteria,1RMBM@1236|Gammaproteobacteria,464U3@72275|Alteromonadaceae	1236|Gammaproteobacteria	G	Catalyzes the NAD-dependent conversion of D-erythrose 4- phosphate to 4-phosphoerythronate	epd	GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016491,GO:0016620,GO:0016903,GO:0017144,GO:0018130,GO:0019318,GO:0019438,GO:0019637,GO:0034641,GO:0036094,GO:0042364,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0043891,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046483,GO:0048001,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055114,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	1.2.1.12,1.2.1.72	ko:K00134,ko:K03472	ko00010,ko00710,ko00750,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map00750,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00124,M00165,M00166,M00308,M00552	R01061,R01825	RC00149,RC00242	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	iYL1228.KPN_03356	Gp_dh_C,Gp_dh_N
k141_8310_1	998674.ATTE01000001_gene2402	3.7e-104	310.0	COG4663@1|root,COG4663@2|Bacteria,1MVMD@1224|Proteobacteria,1RNCK@1236|Gammaproteobacteria,45ZWY@72273|Thiotrichales	72273|Thiotrichales	Q	Part of the tripartite ATP-independent periplasmic (TRAP) transport system	-	-	-	-	-	-	-	-	-	-	-	-	DctP
k141_6507_1	1502770.JQMG01000001_gene522	2.13e-21	97.8	COG0823@1|root,COG0823@2|Bacteria,1MV09@1224|Proteobacteria,2VH9R@28216|Betaproteobacteria,2KKVW@206350|Nitrosomonadales	206350|Nitrosomonadales	U	Involved in the TonB-independent uptake of proteins	tolB	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40,TolB_N
k141_948_1	35128.Thapsdraft1611	5.01e-54	187.0	28JJ8@1|root,2QRYE@2759|Eukaryota,2XEB4@2836|Bacillariophyta	2836|Bacillariophyta	C	PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX. PSI is a plastocyanin cytochrome c6-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn. Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin or cytochrome c6	psaB	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009534,GO:0009535,GO:0009536,GO:0009579,GO:0016020,GO:0016168,GO:0031976,GO:0031984,GO:0034357,GO:0042651,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044436,GO:0044444,GO:0044446,GO:0044464,GO:0046906,GO:0048037,GO:0055035,GO:0097159,GO:1901363	-	ko:K02690	ko00195,ko01100,map00195,map01100	M00163	-	-	ko00000,ko00001,ko00002,ko00194	-	-	-	PsaA_PsaB
k141_4031_1	580332.Slit_2117	2.65e-79	248.0	COG0475@1|root,COG0475@2|Bacteria,1PK6U@1224|Proteobacteria,2WAEY@28216|Betaproteobacteria,44WJS@713636|Nitrosomonadales	28216|Betaproteobacteria	P	Sodium/hydrogen exchanger family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
k141_6508_2	1249627.D779_3353	1.68e-81	269.0	COG0086@1|root,COG0086@2|Bacteria,1MU3M@1224|Proteobacteria,1RPYH@1236|Gammaproteobacteria,1WVVI@135613|Chromatiales	135613|Chromatiales	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	-	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
k141_4656_1	479434.Sthe_0529	1.04e-28	115.0	COG2141@1|root,COG2141@2|Bacteria,2G5MF@200795|Chloroflexi,27Z35@189775|Thermomicrobia	189775|Thermomicrobia	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
k141_2193_1	335992.SAR11_0880	1.92e-51	168.0	COG0740@1|root,COG0740@2|Bacteria,1MV46@1224|Proteobacteria,2TR5M@28211|Alphaproteobacteria,4BPGS@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	OU	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
k141_1569_1	1173028.ANKO01000090_gene3472	3.12e-18	84.7	COG1051@1|root,COG1051@2|Bacteria,1FZVE@1117|Cyanobacteria,1H72E@1150|Oscillatoriales	1117|Cyanobacteria	F	ADP-ribose pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
k141_2800_1	5465.ENH79409	1.38e-05	52.4	COG0500@1|root,KOG1269@2759|Eukaryota,38CU5@33154|Opisthokonta,3PBRQ@4751|Fungi,3R302@4890|Ascomycota,21DEQ@147550|Sordariomycetes,1EZ4H@1028384|Glomerellales	4751|Fungi	H	Catalyzes the methyl transfer from S-adenosyl-methionine to the C-24 of zymosterol to form fecosterol	-	-	2.1.1.41	ko:K00559	ko00100,ko01100,ko01110,ko01130,map00100,map01100,map01110,map01130	M00102	R04427,R07481	RC00003,RC01154	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11,Sterol_MT_C
k141_3397_1	1541065.JRFE01000014_gene1863	2.13e-65	219.0	COG3733@1|root,COG3733@2|Bacteria,1G2YB@1117|Cyanobacteria,3VMF5@52604|Pleurocapsales	1117|Cyanobacteria	Q	Copper amine oxidase, enzyme domain	-	-	1.4.3.21	ko:K00276	ko00260,ko00350,ko00360,ko00410,ko00950,ko00960,ko01100,ko01110,map00260,map00350,map00360,map00410,map00950,map00960,map01100,map01110	-	R02382,R02529,R02613,R03139,R04027,R04300,R06154,R06740	RC00062,RC00189,RC00676,RC01052	ko00000,ko00001,ko01000	-	-	-	Cu_amine_oxid,Cu_amine_oxidN2,Cu_amine_oxidN3
k141_4032_1	694431.DESACE_01900	2.35e-15	75.9	COG0094@1|root,COG0094@2|Bacteria,1MUU9@1224|Proteobacteria,42QS6@68525|delta/epsilon subdivisions,2WMPD@28221|Deltaproteobacteria,2M6GT@213113|Desulfurellales	28221|Deltaproteobacteria	J	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits	rplE	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02931	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L5,Ribosomal_L5_C
k141_4032_2	1158318.ATXC01000001_gene1264	1.41e-30	113.0	COG0093@1|root,COG0093@2|Bacteria,2G41F@200783|Aquificae	200783|Aquificae	J	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome	rplN	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904	-	ko:K02874	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L14
k141_6509_1	159749.K0SGQ3	3.4e-10	65.9	2E06H@1|root,2S7MZ@2759|Eukaryota	2759|Eukaryota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	LysM
k141_5272_1	1111732.AZOD01000004_gene990	4.19e-28	110.0	COG0042@1|root,COG0042@2|Bacteria,1MV5V@1224|Proteobacteria,1RMJP@1236|Gammaproteobacteria,1X3G9@135614|Xanthomonadales	135614|Xanthomonadales	J	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	dusB	-	-	ko:K05540	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Dus
k141_1570_1	1469245.JFBG01000052_gene2169	1.6e-100	299.0	COG4177@1|root,COG4177@2|Bacteria,1NPII@1224|Proteobacteria	1224|Proteobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
k141_9572_1	572477.Alvin_2695	7.71e-49	167.0	COG2304@1|root,COG2304@2|Bacteria,1MXQ7@1224|Proteobacteria,1RMDX@1236|Gammaproteobacteria,1WVYS@135613|Chromatiales	135613|Chromatiales	S	PFAM von Willebrand factor type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA
k141_5273_1	234267.Acid_6263	2.87e-29	120.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
k141_4657_1	164328.Phyra85164	7.6e-21	94.4	KOG3105@1|root,KOG3105@2759|Eukaryota	2759|Eukaryota	CH	DNA binding	SMIM13	-	-	-	-	-	-	-	-	-	-	-	BrkDBD,DDE_1,HTH_Tnp_Tc5,HTH_psq
k141_1571_1	1229909.NSED_08255	4.93e-107	308.0	arCOG08676@1|root,arCOG08676@2157|Archaea,41SCF@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Archaeal ammonia monooxygenase subunit A (AmoA)	-	-	1.14.18.3,1.14.99.39	ko:K10944	ko00680,ko00910,ko01100,ko01120,ko01200,map00680,map00910,map01100,map01120,map01200	M00174,M00528,M00804	R00148,R09518	RC00173,RC02797	ko00000,ko00001,ko00002,ko01000	-	-	-	Archaeal_AmoA
k141_3399_1	452637.Oter_1515	5.02e-48	167.0	COG0845@1|root,COG0845@2|Bacteria,46UZZ@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Biotin-lipoyl like	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
k141_8314_1	1117647.M5M_11105	6.68e-99	306.0	COG0187@1|root,COG0187@2|Bacteria,1MVH1@1224|Proteobacteria,1RMCI@1236|Gammaproteobacteria,1J4HN@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	L	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule	parE	-	-	ko:K02622	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
k141_7683_1	414684.RC1_3169	2.6e-52	176.0	COG0647@1|root,COG0647@2|Bacteria,1MU9Y@1224|Proteobacteria,2TUH0@28211|Alphaproteobacteria,2JQ8Q@204441|Rhodospirillales	204441|Rhodospirillales	G	sugar phosphatases of the HAD superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase,Hydrolase_6,Hydrolase_like
k141_7160_1	388401.RB2150_13191	4.67e-25	103.0	COG2303@1|root,COG2303@2|Bacteria,1MV19@1224|Proteobacteria,2TQKQ@28211|Alphaproteobacteria,3ZGR9@58840|unclassified Rhodobacteraceae	1224|Proteobacteria	C	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate	-	-	1.1.99.1	ko:K00108	ko00260,ko01100,map00260,map01100	M00555	R01025	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	GMC_oxred_C,GMC_oxred_N
k141_7160_2	335284.Pcryo_1018	1.8e-08	55.8	COG0665@1|root,COG0665@2|Bacteria,1MVIZ@1224|Proteobacteria,1RQ50@1236|Gammaproteobacteria,3NMBN@468|Moraxellaceae	1236|Gammaproteobacteria	E	FAD dependent oxidoreductase	-	-	1.4.5.1	ko:K00285	ko00360,map00360	-	R01374,R09493	RC00006,RC00025	ko00000,ko00001,ko01000	-	-	-	DAO
k141_5316_1	1131269.AQVV01000028_gene29	4.44e-100	297.0	COG1262@1|root,COG1262@2|Bacteria	2|Bacteria	T	PFAM Formylglycine-generating sulfatase enzyme	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
k141_991_1	1229909.NSED_05405	7.24e-92	291.0	COG0417@1|root,arCOG15272@2157|Archaea,41S91@651137|Thaumarchaeota	651137|Thaumarchaeota	L	DNA polymerase	-	-	2.7.7.7	ko:K02319	ko00230,ko00240,ko01100,ko03030,map00230,map00240,map01100,map03030	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032	-	-	-	DNA_pol_B,DNA_pol_B_exo1
k141_991_2	436308.Nmar_0949	4.17e-14	66.2	COG4095@1|root,arCOG05022@2157|Archaea,41SUZ@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Sugar efflux transporter for intercellular exchange	-	-	-	ko:K15383	-	-	-	-	ko00000,ko02000	9.A.58.2	-	-	MtN3_slv
k141_9608_1	1238182.C882_2403	6.67e-13	67.0	2C068@1|root,30N9J@2|Bacteria,1RG08@1224|Proteobacteria,2UBBZ@28211|Alphaproteobacteria,2JS3N@204441|Rhodospirillales	204441|Rhodospirillales	S	Protein of unknown function (DUF3035)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3035
k141_9608_2	414684.RC1_3588	1.33e-31	122.0	COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,2TRFB@28211|Alphaproteobacteria,2JQCK@204441|Rhodospirillales	204441|Rhodospirillales	S	Belongs to the peptidase M16 family	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
k141_2847_1	570967.JMLV01000001_gene2876	4.53e-83	267.0	COG2609@1|root,COG2609@2|Bacteria,1MV21@1224|Proteobacteria,2TSZ9@28211|Alphaproteobacteria,2JQNV@204441|Rhodospirillales	204441|Rhodospirillales	C	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	-	-	1.2.4.1	ko:K00163	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	DXP_synthase_N,Transket_pyr,Transketolase_N
k141_3441_2	595460.RRSWK_02241	8.89e-44	154.0	COG4301@1|root,COG4301@2|Bacteria,2IXEH@203682|Planctomycetes	203682|Planctomycetes	S	Histidine-specific methyltransferase, SAM-dependent	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_33
k141_5925_1	10228.TriadP63021	2.39e-89	280.0	COG0072@1|root,KOG2472@2759|Eukaryota,3A7RT@33154|Opisthokonta,3BXEE@33208|Metazoa	33208|Metazoa	J	phenylalanine--tRNA ligase beta	-	-	-	-	-	-	-	-	-	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
k141_4700_1	1229909.NSED_01480	1.45e-22	88.6	COG1698@1|root,arCOG04308@2157|Archaea,41SRP@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Belongs to the UPF0147 family	-	-	-	ko:K09721	-	-	-	-	ko00000	-	-	-	UPF0147
k141_4700_2	1229909.NSED_01485	1.07e-63	195.0	COG2146@1|root,arCOG02852@2157|Archaea,41SSE@651137|Thaumarchaeota	651137|Thaumarchaeota	P	Rieske 2Fe-2S	-	-	-	ko:K05710	ko00360,ko01120,ko01220,map00360,map01120,map01220	M00545	R06782,R06783	RC00098	br01602,ko00000,ko00001,ko00002	-	-	-	Rieske
k141_1613_1	1294273.roselon_01728	9.88e-122	354.0	COG0039@1|root,COG0039@2|Bacteria,1MV57@1224|Proteobacteria,2TSV6@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Catalyzes the reversible oxidation of malate to oxaloacetate	mdh	GO:0003674,GO:0003824,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0016999,GO:0017144,GO:0019752,GO:0030060,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350	1.1.1.37	ko:K00024	ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740	R00342,R07136	RC00031	ko00000,ko00001,ko00002,ko01000	-	-	-	Ldh_1_C,Ldh_1_N
k141_4080_1	1380391.JIAS01000004_gene2992	3.56e-63	207.0	COG0665@1|root,COG0665@2|Bacteria,1PERE@1224|Proteobacteria,2U1FT@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
k141_6547_1	639283.Snov_2843	5.17e-78	248.0	COG0277@1|root,COG0277@2|Bacteria,1MUKV@1224|Proteobacteria,2TVCQ@28211|Alphaproteobacteria,3F0JJ@335928|Xanthobacteraceae	28211|Alphaproteobacteria	C	FAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_4
k141_8956_1	2850.Phatr47650	4.58e-106	348.0	2D25Z@1|root,2SKKF@2759|Eukaryota,2XEGK@2836|Bacillariophyta	2836|Bacillariophyta	-	-	-	-	-	-	-	-	-	-	-	-	-	-	rve
k141_992_1	391624.OIHEL45_01650	0.000521	42.4	COG1214@1|root,COG1214@2|Bacteria,1MXPH@1224|Proteobacteria,2TTM2@28211|Alphaproteobacteria	28211|Alphaproteobacteria	O	COG1214 Inactive homolog of metal-dependent proteases	yeaZ	-	2.3.1.234	ko:K01409,ko:K14742	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
k141_992_2	1123247.AUIJ01000012_gene871	3.34e-86	257.0	COG0694@1|root,COG0694@2|Bacteria,1MVQ1@1224|Proteobacteria,2TUD1@28211|Alphaproteobacteria	28211|Alphaproteobacteria	O	COG0694 Thioredoxin-like proteins and domains	nifU	-	-	-	-	-	-	-	-	-	-	-	Nfu_N,NifU
k141_4701_2	1128912.GMES_1845	5.56e-10	60.8	2CBG9@1|root,32RTB@2|Bacteria,1R86M@1224|Proteobacteria,1RNNN@1236|Gammaproteobacteria,466UG@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Type II secretion system (T2SS), protein N	gspN	GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705	-	ko:K02463	ko05111,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSN
k141_6548_1	575540.Isop_0553	1.26e-56	193.0	COG0056@1|root,COG0056@2|Bacteria,2IXN5@203682|Planctomycetes	203682|Planctomycetes	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
k141_993_1	391626.OAN307_c05680	1.71e-117	345.0	COG2826@1|root,COG2826@2|Bacteria,1PP49@1224|Proteobacteria,2TRVA@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	COG2826 Transposase and inactivated derivatives, IS30 family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_38,rve
k141_3443_1	518766.Rmar_2129	1.22e-97	298.0	COG0334@1|root,COG0334@2|Bacteria,4NEBH@976|Bacteroidetes,1FIWI@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	C	Belongs to the Glu Leu Phe Val dehydrogenases family	gdhA	-	1.4.1.3	ko:K00261	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
k141_2238_1	1082931.KKY_2603	2.42e-101	299.0	COG1484@1|root,COG1484@2|Bacteria,1MWQX@1224|Proteobacteria,2TRGY@28211|Alphaproteobacteria,3N8SG@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	L	IstB-like ATP binding protein	-	-	-	-	-	-	-	-	-	-	-	-	IstB_IS21
k141_6549_1	102129.Lepto7375DRAFT_5059	2.63e-94	296.0	COG0028@1|root,COG2146@1|root,COG0028@2|Bacteria,COG2146@2|Bacteria,1G4R6@1117|Cyanobacteria,1HAC6@1150|Oscillatoriales	1117|Cyanobacteria	H	Thiamine pyrophosphate enzyme, central domain	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
k141_383_2	1123237.Salmuc_02989	1.28e-75	232.0	COG0854@1|root,COG0854@2|Bacteria,1MU9W@1224|Proteobacteria,2TTTF@28211|Alphaproteobacteria	28211|Alphaproteobacteria	H	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate	pdxJ	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	2.6.99.2	ko:K03474	ko00750,ko01100,map00750,map01100	M00124	R05838	RC01476	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxJ
k141_1616_1	1189612.A33Q_0460	2.64e-16	77.4	COG0201@1|root,COG0201@2|Bacteria,4NEPU@976|Bacteroidetes,47JRD@768503|Cytophagia	976|Bacteroidetes	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	-	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
k141_1616_2	1237149.C900_01055	1.17e-47	158.0	COG0200@1|root,COG0200@2|Bacteria,4NNFQ@976|Bacteroidetes,47PP0@768503|Cytophagia	976|Bacteroidetes	J	Binds to the 23S rRNA	rplO	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02876	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27A
k141_1763_1	159749.K0S5M3	4.53e-47	172.0	2D2UX@1|root,2SP3U@2759|Eukaryota,2XG67@2836|Bacillariophyta	2836|Bacillariophyta	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_2382_1	1502851.FG93_02612	8.55e-30	114.0	COG0266@1|root,COG0266@2|Bacteria,1MVM5@1224|Proteobacteria,2TS4C@28211|Alphaproteobacteria,3JRJ8@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	L	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates	fpg	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
k141_2382_2	1185766.DL1_17745	2.32e-72	223.0	COG0500@1|root,COG2226@2|Bacteria,1MX8I@1224|Proteobacteria,2TRWR@28211|Alphaproteobacteria,2XMNM@285107|Thioclava	28211|Alphaproteobacteria	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2)	ubiE	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
k141_1145_1	1131269.AQVV01000003_gene722	2.18e-76	241.0	COG0460@1|root,COG0460@2|Bacteria	2|Bacteria	E	homoserine dehydrogenase activity	hom	GO:0003674,GO:0003824,GO:0004412,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009088,GO:0009987,GO:0016020,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0030312,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.3	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00017,M00018	R01773,R01775	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1294,iSB619.SA_RS06610	ACT,Homoserine_dh,NAD_binding_3
k141_532_1	335659.S23_68310	1.9e-15	73.9	COG3764@1|root,COG3764@2|Bacteria,1P806@1224|Proteobacteria,2U0A5@28211|Alphaproteobacteria,3JWBT@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	M	Sortase family	-	-	3.4.22.70	ko:K07284	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Sortase
k141_532_2	1333998.M2A_2366	2.49e-12	69.3	COG2304@1|root,COG2304@2|Bacteria,1MW8K@1224|Proteobacteria,2TV9Y@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	von Willebrand factor, type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VIT,VWA_3
k141_7298_1	765910.MARPU_00630	2.41e-98	295.0	COG0714@1|root,COG0714@2|Bacteria,1MUFN@1224|Proteobacteria,1RP45@1236|Gammaproteobacteria,1WXIF@135613|Chromatiales	135613|Chromatiales	S	associated with various cellular activities	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
k141_7870_2	35128.Thapsdraft1287	1.09e-254	707.0	COG0056@1|root,KOG1353@2759|Eukaryota,2XEPU@2836|Bacillariophyta	2836|Bacillariophyta	F	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	-	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
k141_1764_1	1380394.JADL01000010_gene4306	1.19e-84	266.0	COG0001@1|root,COG0001@2|Bacteria,1MUY5@1224|Proteobacteria,2U3S7@28211|Alphaproteobacteria,2JR3P@204441|Rhodospirillales	204441|Rhodospirillales	H	Aminotransferase class-III	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_3
k141_533_1	159749.K0RL31	9.91e-36	139.0	COG2801@1|root,KOG0017@2759|Eukaryota,2XF4I@2836|Bacillariophyta	159749.K0RL31|-	L	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_5467_1	666509.RCA23_c04970	3.24e-120	352.0	COG1062@1|root,COG1062@2|Bacteria,1MUK4@1224|Proteobacteria,2TT67@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily	adhC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0008150,GO:0008152,GO:0015945,GO:0034308,GO:0044281,GO:0044424,GO:0044464,GO:0071704,GO:1901615	1.1.1.1,1.1.1.284	ko:K00121	ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R06983,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01715,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
k141_3578_1	269799.Gmet_0975	7.01e-34	135.0	COG4796@1|root,COG4796@2|Bacteria,1QTT6@1224|Proteobacteria,42MKN@68525|delta/epsilon subdivisions,2WJV6@28221|Deltaproteobacteria,43UJ4@69541|Desulfuromonadales	28221|Deltaproteobacteria	U	PFAM type II and III secretion system protein	pilQ	-	-	ko:K02666	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	AMIN,STN,Secretin,Secretin_N
k141_9101_1	2340.JV46_17820	2.39e-21	97.4	COG1538@1|root,COG1538@2|Bacteria,1MWCJ@1224|Proteobacteria,1RQQV@1236|Gammaproteobacteria,1J52S@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	MU	COG1538 Outer membrane protein	tolC	-	-	ko:K12340	ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133	M00325,M00326,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko02044	1.B.17,2.A.6.2	-	-	OEP
k141_6077_1	1485544.JQKP01000011_gene758	1.1e-68	216.0	COG0284@1|root,COG0284@2|Bacteria,1MW2C@1224|Proteobacteria,2VJRD@28216|Betaproteobacteria,44VEZ@713636|Nitrosomonadales	28216|Betaproteobacteria	F	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)	pyrF	-	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase
k141_1146_1	5691.EAN79747	2.77e-56	196.0	COG0209@1|root,KOG1112@2759|Eukaryota,3XTBM@5653|Kinetoplastida	5653|Kinetoplastida	F	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides	-	-	1.17.4.1	ko:K10807	ko00230,ko00240,ko00480,ko00983,ko01100,map00230,map00240,map00480,map00983,map01100	M00053	R02017,R02019,R02024,R08363,R08364,R11893	RC00613,RC01003	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	ATP-cone,Ribonuc_red_lgC,Ribonuc_red_lgN
k141_1146_2	2880.D8LG29	1.68e-28	114.0	COG0209@1|root,KOG1112@2759|Eukaryota	2759|Eukaryota	F	ribonucleoside-diphosphate reductase activity	RNR1	GO:0000166,GO:0003674,GO:0003824,GO:0004550,GO:0004748,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005739,GO:0005829,GO:0005971,GO:0006139,GO:0006165,GO:0006213,GO:0006220,GO:0006221,GO:0006235,GO:0006240,GO:0006259,GO:0006260,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009116,GO:0009117,GO:0009119,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009185,GO:0009186,GO:0009189,GO:0009193,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009218,GO:0009219,GO:0009221,GO:0009259,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0010035,GO:0010038,GO:0016301,GO:0016310,GO:0016491,GO:0016725,GO:0016728,GO:0016740,GO:0016772,GO:0016776,GO:0017076,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0019693,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046062,GO:0046075,GO:0046131,GO:0046385,GO:0046483,GO:0046686,GO:0046704,GO:0046939,GO:0050896,GO:0051063,GO:0055086,GO:0055114,GO:0061731,GO:0071704,GO:0072527,GO:0072528,GO:0090304,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1902494,GO:1990204	1.17.4.1	ko:K10807	ko00230,ko00240,ko00480,ko00983,ko01100,map00230,map00240,map00480,map00983,map01100	M00053	R02017,R02019,R02024,R08363,R08364,R11893	RC00613,RC01003	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	ATP-cone,Ribonuc_red_lgC,Ribonuc_red_lgN
k141_7300_1	1121875.KB907547_gene3100	6.5e-80	249.0	COG2115@1|root,COG2115@2|Bacteria,4NEBQ@976|Bacteroidetes,1HXW8@117743|Flavobacteriia	976|Bacteroidetes	G	Catalyzes the interconversion of D-xylose to D-xylulose	xylA	-	5.3.1.5	ko:K01805	ko00040,ko00051,ko01100,map00040,map00051,map01100	-	R00878,R01432	RC00376,RC00516	ko00000,ko00001,ko01000	-	-	-	-
k141_1765_1	1127673.GLIP_1262	5.3e-22	96.7	COG2211@1|root,COG2211@2|Bacteria,1MWT1@1224|Proteobacteria,1RMID@1236|Gammaproteobacteria,46CM4@72275|Alteromonadaceae	1236|Gammaproteobacteria	G	MFS/sugar transport protein	melB1	-	-	ko:K03292,ko:K16210	-	-	-	-	ko00000,ko02000	2.A.2,2.A.2.5	-	-	MFS_2
k141_1765_2	1379270.AUXF01000003_gene3412	2.21e-32	124.0	COG2211@1|root,COG2211@2|Bacteria,1ZV78@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	MFS/sugar transport protein	-	-	-	ko:K03292	-	-	-	-	ko00000	2.A.2	-	-	MFS_2
k141_534_1	391589.RGAI101_287	3.31e-102	306.0	COG1594@1|root,COG1594@2|Bacteria,1MWK8@1224|Proteobacteria,2U0YM@28211|Alphaproteobacteria,2P1BB@2433|Roseobacter	28211|Alphaproteobacteria	K	COG1198 Primosomal protein N' (replication factor Y) - superfamily II helicase	-	-	-	-	-	-	-	-	-	-	-	-	zf-RRN7
k141_2384_1	911045.PSE_1690	3.08e-74	240.0	COG0581@1|root,COG0581@2|Bacteria,1MUWB@1224|Proteobacteria,2TQYQ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	phosphate transport system permease	pstA	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1,DUF3333
k141_3001_2	1268237.G114_11145	9.84e-37	136.0	COG0845@1|root,COG0845@2|Bacteria,1MUI8@1224|Proteobacteria,1RNK4@1236|Gammaproteobacteria,1Y3MF@135624|Aeromonadales	135624|Aeromonadales	M	secretion protein HlyD family	-	-	-	ko:K12542	-	M00330	-	-	ko00000,ko00002,ko02000,ko02044	3.A.1.109.4,8.A.1	-	-	Biotin_lipoyl_2,HlyD,HlyD_3
k141_8509_1	1123247.AUIJ01000002_gene2356	2.76e-39	134.0	COG0346@1|root,COG0346@2|Bacteria,1N116@1224|Proteobacteria,2UC5P@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	COG0346 Lactoylglutathione lyase and related lyases	-	-	-	ko:K07032	-	-	-	-	ko00000	-	-	-	Glyoxalase
k141_5468_1	395493.BegalDRAFT_0212	1.79e-156	449.0	COG3278@1|root,COG3278@2|Bacteria,1MU18@1224|Proteobacteria,1RM7I@1236|Gammaproteobacteria,460AT@72273|Thiotrichales	72273|Thiotrichales	C	Belongs to the heme-copper respiratory oxidase family	-	-	1.9.3.1	ko:K00404	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	COX1
k141_4851_1	246200.SPO1064	2.42e-26	110.0	COG0631@1|root,COG0631@2|Bacteria,1MVE7@1224|Proteobacteria,2U6K4@28211|Alphaproteobacteria,4NAQ5@97050|Ruegeria	28211|Alphaproteobacteria	T	Serine/threonine phosphatases, family 2C, catalytic domain	-	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C_2
k141_6697_1	452638.Pnec_1707	2.82e-52	180.0	COG1207@1|root,COG1207@2|Bacteria,1MUPH@1224|Proteobacteria,2VH54@28216|Betaproteobacteria,1K0PE@119060|Burkholderiaceae	28216|Betaproteobacteria	M	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain	glmU	-	2.3.1.157,2.7.7.23	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00362	R00416,R05332	RC00002,RC00004,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,Hexapep_2,NTP_transf_3
k141_3579_2	1128427.KB904821_gene2642	1.62e-78	255.0	COG0443@1|root,COG0443@2|Bacteria,1G0AK@1117|Cyanobacteria	1117|Cyanobacteria	O	Heat shock 70 kDa protein	-	-	-	-	-	-	-	-	-	-	-	-	HSP70
k141_1148_1	396588.Tgr7_1528	1.92e-83	259.0	COG1322@1|root,COG1322@2|Bacteria,1MWHV@1224|Proteobacteria,1RMB8@1236|Gammaproteobacteria,1WYRX@135613|Chromatiales	135613|Chromatiales	S	RmuC family	-	-	-	ko:K09760	-	-	-	-	ko00000	-	-	-	RmuC
k141_2385_1	754476.Q7A_815	5.41e-64	207.0	COG5345@1|root,COG5345@2|Bacteria,1MWVH@1224|Proteobacteria,1RP5X@1236|Gammaproteobacteria,4625H@72273|Thiotrichales	72273|Thiotrichales	S	protein conserved in bacteria (DUF2333)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2333
k141_6698_1	1469245.JFBG01000054_gene2114	1.11e-78	256.0	COG0404@1|root,COG0665@1|root,COG0404@2|Bacteria,COG0665@2|Bacteria,1MUXJ@1224|Proteobacteria,1RZZE@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Belongs to the GcvT family	-	-	-	-	-	-	-	-	-	-	-	-	DAO,FAO_M,GCV_T,GCV_T_C
k141_4237_3	159749.K0TBF7	2.78e-10	63.9	COG2801@1|root,KOG0017@2759|Eukaryota,2XEDA@2836|Bacillariophyta	2836|Bacillariophyta	L	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	RVT_2
k141_9103_2	398527.Bphyt_4194	3.25e-22	94.0	COG0583@1|root,COG0583@2|Bacteria,1MWY0@1224|Proteobacteria,2VIUZ@28216|Betaproteobacteria,1K0MZ@119060|Burkholderiaceae	28216|Betaproteobacteria	K	transcriptional Regulator, LysR family	-	-	-	ko:K03566	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_1,LysR_substrate
k141_9753_1	1574422.A0A0A1ENW9_9CIRC	4.78e-13	73.6	4QB1C@10239|Viruses,4QUKV@29258|ssDNA viruses	10239|Viruses	S	ATPase activity, uncoupled	-	GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039682,GO:0039684,GO:0039687,GO:0039693,GO:0044403,GO:0044419,GO:0051704	-	-	-	-	-	-	-	-	-	-	-
k141_4853_1	35128.Thapsdraft974	1.54e-20	83.2	2CRSZ@1|root,2R904@2759|Eukaryota,2XHB9@2836|Bacillariophyta	2836|Bacillariophyta	S	Protein of unknown function (DUF751)	ycf33	-	-	-	-	-	-	-	-	-	-	-	DUF751
k141_5470_2	45151.EDU40024	6.16e-17	75.9	COG0185@1|root,KOG0899@2759|Eukaryota,3A5KT@33154|Opisthokonta,3P54F@4751|Fungi,3QXC1@4890|Ascomycota,202UV@147541|Dothideomycetes	4751|Fungi	J	Belongs to the universal ribosomal protein uS19 family	RSM19	GO:0000028,GO:0000313,GO:0000314,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005761,GO:0005763,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0031974,GO:0032543,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0065003,GO:0070013,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0098798,GO:0140053,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	-	-	-	-	-	-	-	-	-	Ribosomal_S19
k141_5470_3	55529.EKX36269	7.52e-23	95.5	COG0090@1|root,KOG0438@2759|Eukaryota	2759|Eukaryota	J	structural constituent of ribosome	-	-	-	-	-	-	-	-	-	-	-	-	Ribosomal_L2,Ribosomal_L2_C
k141_3003_1	111781.Lepto7376_0868	9.56e-89	281.0	COG0443@1|root,COG0443@2|Bacteria,1G1BJ@1117|Cyanobacteria,1H8YA@1150|Oscillatoriales	1117|Cyanobacteria	O	Heat shock 70 kDa protein	dnaK2	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
k141_7874_1	1163617.SCD_n01883	4.47e-60	206.0	COG1148@1|root,COG1908@1|root,COG1148@2|Bacteria,COG1908@2|Bacteria,1MWAG@1224|Proteobacteria,2WEVG@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Methyl-viologen-reducing hydrogenase, delta subunit	-	-	-	ko:K16886	-	-	-	-	ko00000	-	-	-	Fer4,FlpD,Pyr_redox_2
k141_7874_2	1049564.TevJSym_ag00680	3.49e-33	125.0	COG1148@1|root,COG1148@2|Bacteria,1Q0ZF@1224|Proteobacteria,1RYIC@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	FAD dependent oxidoreductase	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388,ko:K16885	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_oxidored,Pyr_redox_2
k141_3581_1	648757.Rvan_0600	2.76e-95	289.0	COG2221@1|root,COG2221@2|Bacteria,1MWY5@1224|Proteobacteria,2U4HS@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	sulfite reductase	-	-	1.8.99.5	ko:K11180	ko00633,ko00920,ko01100,ko01120,map00633,map00920,map01100,map01120	M00596	R00295,R00861,R08035	RC00065,RC01760	ko00000,ko00001,ko00002,ko01000	-	-	-	NIR_SIR,NIR_SIR_ferr
k141_2386_1	159749.E7BWP5	8.76e-62	200.0	COG0050@1|root,KOG0460@2759|Eukaryota,2XBKK@2836|Bacillariophyta	2759|Eukaryota	J	Elongation factor Tu	tufA	GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005634,GO:0005730,GO:0005737,GO:0009295,GO:0009507,GO:0009526,GO:0009532,GO:0009534,GO:0009535,GO:0009536,GO:0009570,GO:0009579,GO:0009941,GO:0016020,GO:0020011,GO:0031967,GO:0031974,GO:0031975,GO:0031976,GO:0031981,GO:0031984,GO:0034357,GO:0042651,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044422,GO:0044424,GO:0044428,GO:0044434,GO:0044435,GO:0044436,GO:0044444,GO:0044446,GO:0044464,GO:0048046,GO:0055035,GO:0070013	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
k141_2386_2	159749.E7BWP4	1.17e-87	259.0	COG0049@1|root,KOG3291@2759|Eukaryota	2759|Eukaryota	J	rRNA binding	rps7	GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009507,GO:0009536,GO:0009579,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02992	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S7
k141_6700_1	616991.JPOO01000003_gene1296	4.52e-142	410.0	COG2871@1|root,COG2871@2|Bacteria,4NFKC@976|Bacteroidetes,1HWV9@117743|Flavobacteriia,23H1R@178469|Arenibacter	976|Bacteroidetes	C	Oxidoreductase FAD-binding domain	nqrF	-	1.6.5.8	ko:K00351	-	-	-	-	ko00000,ko01000	-	-	-	FAD_binding_6,Fer2,NAD_binding_1
k141_4239_1	349521.HCH_06958	8.28e-60	196.0	COG0133@1|root,COG0133@2|Bacteria,1MUS8@1224|Proteobacteria,1RNVE@1236|Gammaproteobacteria,1XIEQ@135619|Oceanospirillales	135619|Oceanospirillales	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	-	-	4.2.1.20	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
k141_2387_1	930169.B5T_04373	3.91e-38	146.0	COG0210@1|root,COG0210@2|Bacteria,1MU0G@1224|Proteobacteria,1RNJI@1236|Gammaproteobacteria,1XIU4@135619|Oceanospirillales	135619|Oceanospirillales	L	Unwinds DNA duplexes with 3' to 5' polarity with respect to the bound strand and initiates unwinding most effectively when a single-stranded region is present	uvrD	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
k141_7305_1	292.DM42_6612	3.59e-69	224.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,2VHQD@28216|Betaproteobacteria,1K09N@119060|Burkholderiaceae	28216|Betaproteobacteria	C	Aldehyde dehydrogenase	-	-	1.2.1.3,1.2.1.8	ko:K00128,ko:K00130	ko00010,ko00053,ko00071,ko00260,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00260,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135,M00555	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02565,R02566,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
k141_7962_1	84531.JMTZ01000012_gene2933	1.57e-64	219.0	COG1629@1|root,COG4771@2|Bacteria,1MWKN@1224|Proteobacteria,1RMM6@1236|Gammaproteobacteria,1X2Y6@135614|Xanthomonadales	135614|Xanthomonadales	P	TonB-dependent Receptor Plug Domain	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
k141_9198_1	94122.Shewana3_2767	1.43e-53	181.0	COG1024@1|root,COG1024@2|Bacteria,1MU0B@1224|Proteobacteria,1RN07@1236|Gammaproteobacteria,2QA0W@267890|Shewanellaceae	1236|Gammaproteobacteria	I	PFAM Enoyl-CoA hydratase isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_2
k141_8603_1	439496.RBY4I_658	2.09e-163	468.0	COG0008@1|root,COG0008@2|Bacteria,1MUCR@1224|Proteobacteria,2TRCI@28211|Alphaproteobacteria	28211|Alphaproteobacteria	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX1	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
k141_9200_1	1430440.MGMSRv2_3751	1.67e-11	60.5	2E4EA@1|root,32Z9I@2|Bacteria,1N7HE@1224|Proteobacteria,2UG09@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_7400_1	998088.B565_1910	1.02e-85	277.0	COG0188@1|root,COG0188@2|Bacteria,1MUGG@1224|Proteobacteria,1RN03@1236|Gammaproteobacteria,1Y403@135624|Aeromonadales	135624|Aeromonadales	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
k141_7966_1	644076.SCH4B_0196	1.82e-77	236.0	COG4584@1|root,COG4584@2|Bacteria,1MWIV@1224|Proteobacteria,2TTHU@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	PFAM Integrase catalytic region	-	-	-	-	-	-	-	-	-	-	-	-	HTH_29,rve
k141_1230_1	130081.XP_005704986.1	5.85e-42	154.0	COG1333@1|root,2QRFF@2759|Eukaryota	2759|Eukaryota	O	cytochrome complex assembly	ccs1	-	-	ko:K07399	-	-	-	-	ko00000	-	-	-	ResB
k141_9201_1	698440.XP_007297771.1	1.31e-19	99.0	COG2801@1|root,KOG0017@2759|Eukaryota,38DPC@33154|Opisthokonta,3NUZ7@4751|Fungi,3QNZW@4890|Ascomycota	4751|Fungi	L	retrotransposon	-	-	-	-	-	-	-	-	-	-	-	-	RVT_2,Retrotran_gag_2,rve
k141_7968_1	2850.Phatr9509	2.85e-15	76.3	COG0445@1|root,KOG2667@2759|Eukaryota,2XFHH@2836|Bacillariophyta	2836|Bacillariophyta	U	Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC)	-	-	-	ko:K20367	-	-	-	-	ko00000,ko04131	-	-	-	COPIIcoated_ERV,ERGIC_N
k141_9202_1	436308.Nmar_1773	1.07e-95	293.0	COG0668@1|root,arCOG01568@2157|Archaea,41SYX@651137|Thaumarchaeota	651137|Thaumarchaeota	M	Mechanosensitive ion channel	-	-	-	ko:K05802	-	-	-	-	ko00000,ko02000	1.A.23.1.1	-	-	MS_channel
k141_8606_1	261292.Nit79A3_0953	4.75e-68	228.0	COG3039@1|root,COG3039@2|Bacteria,1R6NB@1224|Proteobacteria,2W14S@28216|Betaproteobacteria	28216|Betaproteobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_1233_1	999550.KI421507_gene1148	1.46e-58	183.0	2DNR3@1|root,32YQ5@2|Bacteria,1N6UX@1224|Proteobacteria,2UG7C@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440
k141_9848_1	1049564.TevJSym_aj00300	4.53e-36	135.0	COG0707@1|root,COG0707@2|Bacteria,1MVIB@1224|Proteobacteria,1RMQ3@1236|Gammaproteobacteria,1J4FG@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008194,GO:0008375,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0050511,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	iSFV_1184.SFV_0083,iSF_1195.SF0087,iSFxv_1172.SFxv_0091,iS_1188.S0089	Glyco_tran_28_C,Glyco_transf_28
k141_3675_2	159749.K0RL31	1.02e-12	69.7	COG2801@1|root,KOG0017@2759|Eukaryota,2XF4I@2836|Bacillariophyta	159749.K0RL31|-	L	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_7975_1	1380391.JIAS01000001_gene2815	2.38e-73	239.0	COG0633@1|root,COG3894@1|root,COG0633@2|Bacteria,COG3894@2|Bacteria,1MV6C@1224|Proteobacteria,2TUJB@28211|Alphaproteobacteria,2JQGJ@204441|Rhodospirillales	204441|Rhodospirillales	C	Domain of unknown function (DUF4445)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4445,Fer2
k141_3678_1	367336.OM2255_08696	1.16e-70	216.0	COG0251@1|root,COG0251@2|Bacteria,1RHMZ@1224|Proteobacteria,2U9H4@28211|Alphaproteobacteria	28211|Alphaproteobacteria	J	translation initiation inhibitor, yjgF family	-	-	-	-	-	-	-	-	-	-	-	-	YjgF_endoribonc
k141_8611_1	153948.NAL212_2466	8.03e-47	159.0	COG3039@1|root,COG3039@2|Bacteria,1Q94R@1224|Proteobacteria,2WC7J@28216|Betaproteobacteria,374EG@32003|Nitrosomonadales	28216|Betaproteobacteria	L	PFAM Transposase, IS4-like	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DUF772
k141_8612_1	744979.R2A130_3345	2.88e-105	310.0	COG3639@1|root,COG3639@2|Bacteria,1MUD6@1224|Proteobacteria,2TTVG@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	COG3639 ABC-type phosphate phosphonate transport system permease component	phnE_2	-	-	ko:K02042	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	BPD_transp_1
k141_7977_1	633131.TR2A62_1875	1.5e-46	165.0	COG0382@1|root,COG0382@2|Bacteria,1MXCM@1224|Proteobacteria,2TS0Z@28211|Alphaproteobacteria	28211|Alphaproteobacteria	H	COG0382 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	HAD,UbiA
k141_7977_2	314271.RB2654_21418	2.13e-48	160.0	COG0300@1|root,COG0300@2|Bacteria,1NGXF@1224|Proteobacteria,2TTWH@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	MA20_24385	-	-	-	-	-	-	-	-	-	-	-	adh_short
k141_6680_1	1267533.KB906738_gene2329	7.53e-87	272.0	COG0459@1|root,COG0459@2|Bacteria,3Y37I@57723|Acidobacteria,2JIV1@204432|Acidobacteriia	204432|Acidobacteriia	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	-	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
k141_6058_1	929562.Emtol_3462	4.74e-68	224.0	COG0034@1|root,COG0034@2|Bacteria,4NFSM@976|Bacteroidetes,47JRN@768503|Cytophagia	976|Bacteroidetes	F	PFAM Glutamine amidotransferase, class-II	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_6,GATase_7
k141_5452_1	2340.JV46_05960	1.74e-60	210.0	COG0458@1|root,COG0458@2|Bacteria,1MUDZ@1224|Proteobacteria,1RPIU@1236|Gammaproteobacteria,1J5E8@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	F	Carbamoyl-phosphate synthetase ammonia chain	carB	GO:0000050,GO:0000166,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005951,GO:0006082,GO:0006139,GO:0006206,GO:0006220,GO:0006221,GO:0006520,GO:0006525,GO:0006526,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016053,GO:0016597,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0018130,GO:0019438,GO:0019627,GO:0019637,GO:0019693,GO:0019752,GO:0019856,GO:0030554,GO:0031406,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046394,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0071941,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	iAF1260.b0033,iBWG_1329.BWG_0031,iECDH10B_1368.ECDH10B_0034,iECDH1ME8569_1439.ECDH1ME8569_0031,iECUMN_1333.ECUMN_0034,iEcDH1_1363.EcDH1_3566,iJN746.PP_4723,iJO1366.b0033,iJR904.b0033,iPC815.YPO0482,iY75_1357.Y75_RS00170,iYL1228.KPN_00041	CPSase_L_D2,CPSase_L_D3,MGS
k141_2368_1	616991.JPOO01000001_gene3453	1.05e-85	263.0	COG0801@1|root,COG1428@1|root,COG0801@2|Bacteria,COG1428@2|Bacteria,4NGE8@976|Bacteroidetes,1HWTH@117743|Flavobacteriia,23GV2@178469|Arenibacter	976|Bacteroidetes	FH	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)	folK	-	2.7.6.3	ko:K00950	ko00790,ko01100,map00790,map01100	M00126,M00841	R03503	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HPPK,dNK
k141_7858_1	998674.ATTE01000001_gene2236	1.63e-66	217.0	COG0076@1|root,COG0076@2|Bacteria,1MWUX@1224|Proteobacteria,1RY33@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	decarboxylase	-	-	4.1.1.105,4.1.1.28	ko:K01593	ko00350,ko00360,ko00380,ko00901,ko00950,ko00965,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00350,map00360,map00380,map00901,map00950,map00965,map01100,map01110,map04726,map04728,map05030,map05031,map05034	M00037,M00042	R00685,R00699,R00736,R02080,R02701,R04909	RC00299	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyridoxal_deC
k141_9086_1	401053.AciPR4_0872	1.22e-70	224.0	COG1077@1|root,COG1077@2|Bacteria,3Y3VC@57723|Acidobacteria,2JHQ2@204432|Acidobacteriia	204432|Acidobacteriia	D	cell shape determining protein MreB	-	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
k141_9742_1	406817.XNC1_4455	1.13e-86	256.0	COG3293@1|root,COG3293@2|Bacteria,1RBFK@1224|Proteobacteria,1S22S@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Pfam Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4096
k141_567_1	1209072.ALBT01000061_gene976	9.55e-97	289.0	COG0106@1|root,COG0106@2|Bacteria,1MW6S@1224|Proteobacteria,1RN3M@1236|Gammaproteobacteria,1FGZ8@10|Cellvibrio	1236|Gammaproteobacteria	E	Histidine biosynthesis protein	hisA	-	5.3.1.16,5.3.1.24	ko:K01814,ko:K01817	ko00340,ko00400,ko01100,ko01110,ko01130,ko01230,map00340,map00400,map01100,map01110,map01130,map01230	M00023,M00026	R03509,R04640	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
k141_567_2	713586.KB900536_gene2347	1.18e-29	111.0	COG0118@1|root,COG0118@2|Bacteria,1MU4X@1224|Proteobacteria,1RRP3@1236|Gammaproteobacteria,1WWF1@135613|Chromatiales	135613|Chromatiales	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR	hisH	-	-	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
k141_8549_1	765914.ThisiDRAFT_2074	1.57e-89	273.0	COG0473@1|root,COG0473@2|Bacteria,1MUH4@1224|Proteobacteria,1RMZQ@1236|Gammaproteobacteria,1WVY0@135613|Chromatiales	135613|Chromatiales	CE	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate	leuB	-	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
k141_7909_1	159749.E7BWK9	2.03e-67	219.0	COG0459@1|root,KOG0356@2759|Eukaryota,2XBJD@2836|Bacillariophyta	2759|Eukaryota	O	Belongs to the chaperonin (HSP60) family	groL	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009536,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
k141_1181_1	309807.SRU_1182	1.38e-68	233.0	COG0841@1|root,COG0841@2|Bacteria,4NDZG@976|Bacteroidetes,1FIX7@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
k141_6733_1	743720.Psefu_0421	8.87e-35	136.0	COG5009@1|root,COG5009@2|Bacteria,1MU5A@1224|Proteobacteria,1RM7J@1236|Gammaproteobacteria,1YXQ8@136845|Pseudomonas putida group	1236|Gammaproteobacteria	M	Penicillin-binding protein 1A	mrcA	GO:0000270,GO:0003674,GO:0003824,GO:0004180,GO:0004185,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006023,GO:0006024,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0008360,GO:0008658,GO:0008955,GO:0009002,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0016758,GO:0016787,GO:0017171,GO:0019538,GO:0022603,GO:0022604,GO:0030203,GO:0031224,GO:0031226,GO:0031406,GO:0033218,GO:0033293,GO:0034645,GO:0036094,GO:0042221,GO:0042546,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044425,GO:0044459,GO:0044464,GO:0046677,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051128,GO:0065007,GO:0065008,GO:0070008,GO:0070011,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:0140096,GO:1901135,GO:1901137,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	PCB_OB,Transgly,Transpeptidase
k141_4273_2	35128.Thapsdraft1754	2.33e-55	201.0	COG2801@1|root,KOG0017@2759|Eukaryota,2XEDA@2836|Bacillariophyta	2836|Bacillariophyta	L	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	RVT_2
k141_5506_1	1231392.OCGS_0309	1.22e-114	340.0	COG0055@1|root,COG0055@2|Bacteria,1MUFU@1224|Proteobacteria,2TRGP@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
k141_3618_1	428125.CLOLEP_00476	2.88e-30	119.0	COG1180@1|root,COG1180@2|Bacteria,1TPK2@1239|Firmicutes,24871@186801|Clostridia	186801|Clostridia	C	glycyl-radical enzyme activating protein family	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM
k141_6118_1	159749.E7BWD9	2.76e-76	229.0	COG0355@1|root,KOG1758@2759|Eukaryota	2759|Eukaryota	C	proton-transporting ATP synthase activity, rotational mechanism	atpE	GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02114,ko:K02134	ko00190,ko00195,ko01100,ko04714,ko05010,ko05012,ko05016,map00190,map00195,map01100,map04714,map05010,map05012,map05016	M00157,M00158	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_DE,ATP-synt_DE_N,PPR
k141_7341_1	323261.Noc_2381	1.53e-85	276.0	COG0542@1|root,COG0542@2|Bacteria,1MURH@1224|Proteobacteria,1RN55@1236|Gammaproteobacteria,1WWC8@135613|Chromatiales	135613|Chromatiales	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
k141_1807_1	694440.JOMF01000006_gene581	7.3e-21	91.7	COG0548@1|root,arCOG00862@2157|Archaea,2XTW9@28890|Euryarchaeota,2N912@224756|Methanomicrobia	224756|Methanomicrobia	E	Belongs to the acetylglutamate kinase family. ArgB subfamily	argB	-	2.7.2.8	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R02649	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
k141_1807_2	688246.Premu_0863	1.43e-17	85.1	COG0078@1|root,COG0078@2|Bacteria,4NEYX@976|Bacteroidetes,2FNR9@200643|Bacteroidia	976|Bacteroidetes	E	Belongs to the ATCase OTCase family	argF	GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.1.3.11,2.1.3.9	ko:K09065,ko:K13043	ko00220,ko01100,ko01230,map00220,map01100,map01230	M00845	R07245,R08937	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
k141_6734_1	314264.ROS217_07330	3.47e-11	63.2	COG1177@1|root,COG1177@2|Bacteria,1MUQD@1224|Proteobacteria,2U1YB@28211|Alphaproteobacteria,46NZR@74030|Roseovarius	28211|Alphaproteobacteria	P	COG1177 ABC-type spermidine putrescine transport system, permease component II	-	-	-	ko:K02053	ko02024,map02024	M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11	-	-	BPD_transp_1
k141_3039_1	690850.Desaf_0046	8.77e-68	223.0	COG0008@1|root,COG0008@2|Bacteria,1MUC8@1224|Proteobacteria,42MAX@68525|delta/epsilon subdivisions,2WJ5B@28221|Deltaproteobacteria,2M7XR@213115|Desulfovibrionales	28221|Deltaproteobacteria	J	PFAM Glutamyl glutaminyl-tRNA synthetase, class Ic, catalytic	glnS	-	6.1.1.18	ko:K01886	ko00970,ko01100,map00970,map01100	M00359,M00360	R03652	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	GatB_Yqey,tRNA-synt_1c,tRNA-synt_1c_C
k141_4274_1	1229909.NSED_07060	5.49e-136	395.0	COG2132@1|root,arCOG03914@2157|Archaea,41SZT@651137|Thaumarchaeota	651137|Thaumarchaeota	Q	Multicopper oxidase	-	-	1.7.2.1	ko:K00368	ko00910,ko01120,map00910,map01120	M00529	R00783,R00785	RC00086	ko00000,ko00001,ko00002,ko01000	-	-	-	Cu-oxidase_3
k141_3619_1	436308.Nmar_1066	1.61e-117	346.0	COG0017@1|root,arCOG00406@2157|Archaea,41S93@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)	-	-	-	-	-	-	-	-	-	-	-	-	tRNA-synt_2,tRNA_anti-codon
k141_6119_1	394.NGR_a02050	2.19e-61	194.0	COG3415@1|root,COG3415@2|Bacteria,1RDMQ@1224|Proteobacteria,2U6V9@28211|Alphaproteobacteria,4BEPN@82115|Rhizobiaceae	28211|Alphaproteobacteria	L	protein y4pG y4sC	-	-	-	-	-	-	-	-	-	-	-	-	HTH_29,HTH_32,HTH_33
k141_7912_1	68170.KL590544_gene764	4.63e-72	231.0	COG2152@1|root,COG2152@2|Bacteria,2HNS8@201174|Actinobacteria,4EA2Q@85010|Pseudonocardiales	201174|Actinobacteria	G	beta-1,4-mannooligosaccharide phosphorylase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_130
k141_8551_1	4932.YHR031C	1.54e-07	61.2	COG0507@1|root,KOG0987@2759|Eukaryota,38G42@33154|Opisthokonta,3NTY9@4751|Fungi,3QPI6@4890|Ascomycota,3RR5B@4891|Saccharomycetes,3RY67@4893|Saccharomycetaceae	4751|Fungi	L	5' to 3' DNA replicative helicase recruited to paused replisomes to promote fork progression throughout nonhistone protein-DNA complexes, naturally occurring impediments that are encountered in each S phase where replication forks pauses. Required for timely replication of the telomere and subtelomeric DNA and for wild-type levels of telomeric silencing. Involved in DNA repair during stalled replication fork, regulation of fragile sites expression and essential for genome stability. Plays also a role in mtDNA replication. Has G-quadruplex (G4) unwinding activity and can suppress G4-induced genome instability when PIF1 levels are low	RRM3	GO:0000002,GO:0000228,GO:0000781,GO:0000784,GO:0000785,GO:0000790,GO:0000792,GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0004857,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005657,GO:0005694,GO:0005720,GO:0005724,GO:0005737,GO:0005739,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006275,GO:0006725,GO:0006807,GO:0006996,GO:0007005,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010521,GO:0010556,GO:0010558,GO:0010605,GO:0010639,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019219,GO:0019222,GO:0030234,GO:0031297,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031933,GO:0031974,GO:0031981,GO:0032204,GO:0032205,GO:0032210,GO:0032211,GO:0032392,GO:0032508,GO:0033043,GO:0033044,GO:0034641,GO:0034645,GO:0042623,GO:0043086,GO:0043139,GO:0043141,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043596,GO:0044092,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044444,GO:0044446,GO:0044454,GO:0044464,GO:0044806,GO:0045005,GO:0045934,GO:0046483,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051052,GO:0051053,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051276,GO:0051338,GO:0051348,GO:0051972,GO:0051974,GO:0060255,GO:0065007,GO:0065008,GO:0065009,GO:0070013,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0071932,GO:0080090,GO:0090304,GO:0090329,GO:0097046,GO:0098687,GO:0098772,GO:0140097,GO:1901360,GO:1901576,GO:1904356,GO:1904357,GO:2000112,GO:2000113,GO:2000278,GO:2000279,GO:2000621,GO:2001251	3.6.4.12	ko:K15255	-	-	-	-	ko00000,ko01000,ko03029,ko03032	-	-	-	Herpes_Helicase,PIF1
k141_6735_1	640081.Dsui_3398	2.45e-71	227.0	COG2826@1|root,COG2826@2|Bacteria,1PP49@1224|Proteobacteria,2VI0E@28216|Betaproteobacteria,2KVNH@206389|Rhodocyclales	206389|Rhodocyclales	L	PFAM Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_38,rve
k141_3040_1	1127673.GLIP_0461	5.96e-13	74.3	COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,1NAZC@1224|Proteobacteria,1S063@1236|Gammaproteobacteria,464UR@72275|Alteromonadaceae	1236|Gammaproteobacteria	P	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
k141_9143_1	396588.Tgr7_1594	3.32e-110	329.0	COG1350@1|root,COG1350@2|Bacteria,1N07Y@1224|Proteobacteria,1RMGK@1236|Gammaproteobacteria,1WWHA@135613|Chromatiales	135613|Chromatiales	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	-	-	4.2.1.20	ko:K06001	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
k141_2424_1	1035839.AFNK01000029_gene1333	1.48e-09	52.8	2DR8E@1|root,33ANS@2|Bacteria,1NI69@1224|Proteobacteria,1SH0M@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_4887_1	1177154.Y5S_01713	3.09e-63	218.0	COG4105@1|root,COG4105@2|Bacteria,1QVQ9@1224|Proteobacteria,1RSIG@1236|Gammaproteobacteria,1XI5R@135619|Oceanospirillales	135619|Oceanospirillales	S	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16
k141_6120_1	278197.PEPE_1403	4.31e-05	44.3	COG0097@1|root,COG0097@2|Bacteria,1V1FC@1239|Firmicutes,4HFQD@91061|Bacilli,3F4G5@33958|Lactobacillaceae	91061|Bacilli	J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center	rplF	GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02933	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L6
k141_6120_2	326297.Sama_0227	5.12e-56	177.0	COG0096@1|root,COG0096@2|Bacteria,1RDG3@1224|Proteobacteria,1S452@1236|Gammaproteobacteria,2QBN5@267890|Shewanellaceae	1236|Gammaproteobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit	rpsH	GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009894,GO:0009987,GO:0010467,GO:0010468,GO:0010608,GO:0015935,GO:0016043,GO:0019219,GO:0019222,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0031323,GO:0031329,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043487,GO:0043488,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0061013,GO:0065003,GO:0065007,GO:0065008,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903311,GO:1990904	-	ko:K02994	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S8
k141_570_1	886293.Sinac_4025	5.06e-83	275.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,2IXZY@203682|Planctomycetes	203682|Planctomycetes	T	COG0515 Serine threonine protein	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_10,TPR_11,TPR_12,TPR_8,WD40
k141_7913_1	706587.Desti_0038	6.89e-21	96.7	COG0457@1|root,COG1352@1|root,COG0457@2|Bacteria,COG1352@2|Bacteria,1R6N1@1224|Proteobacteria,42NZW@68525|delta/epsilon subdivisions,2WMDS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	NT	PFAM MCP methyltransferase, CheR-type	-	-	2.1.1.80	ko:K00575	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheR,TPR_16,TPR_8
k141_9144_1	488538.SAR116_0069	1.93e-59	199.0	COG5598@1|root,COG5598@2|Bacteria,1R6EK@1224|Proteobacteria,2U3G2@28211|Alphaproteobacteria	28211|Alphaproteobacteria	H	Trimethylamine methyltransferase (MTTB)	-	-	2.1.1.250	ko:K14083	ko00680,ko01120,ko01200,map00680,map01120,map01200	M00563	R09124,R10016	RC00035,RC00732,RC01144,RC02984	ko00000,ko00001,ko00002,ko01000	-	-	-	MTTB
k141_7343_1	493475.GARC_4958	6e-42	152.0	COG1194@1|root,COG1194@2|Bacteria,1MUD4@1224|Proteobacteria,1RMBT@1236|Gammaproteobacteria,4642P@72275|Alteromonadaceae	1236|Gammaproteobacteria	L	COG1194 A G-specific DNA glycosylase	mutY	GO:0003674,GO:0003824,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360	-	ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD,NUDIX_4
k141_6121_1	1163409.UUA_04133	4.07e-11	60.5	COG2963@1|root,COG2963@2|Bacteria	2|Bacteria	L	transposase activity	-	-	-	ko:K07483	-	-	-	-	ko00000	-	-	-	HTH_Tnp_1
k141_6121_2	1163408.UU9_09252	4.77e-67	211.0	COG2801@1|root,COG2801@2|Bacteria,1MVXQ@1224|Proteobacteria,1RYX7@1236|Gammaproteobacteria,1XCRJ@135614|Xanthomonadales	135614|Xanthomonadales	L	DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_21,rve
k141_1810_1	998674.ATTE01000001_gene4144	6.25e-71	229.0	COG2303@1|root,COG2303@2|Bacteria,1MV19@1224|Proteobacteria,1RMD2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate	-	-	1.1.99.1	ko:K00108	ko00260,ko01100,map00260,map01100	M00555	R01025	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	GMC_oxred_C,GMC_oxred_N
k141_6737_1	998674.ATTE01000001_gene2233	2.98e-84	273.0	COG1643@1|root,COG1643@2|Bacteria,1MUEQ@1224|Proteobacteria,1RR1B@1236|Gammaproteobacteria,461TY@72273|Thiotrichales	72273|Thiotrichales	L	ATP-dependent helicase HrpB	-	-	3.6.4.13	ko:K03579	-	-	-	-	ko00000,ko01000	-	-	-	DEAD,HA2,Helicase_C,HrpB_C
k141_3622_1	1122218.KB893654_gene2031	2.82e-14	72.4	COG0795@1|root,COG0795@2|Bacteria,1MUF2@1224|Proteobacteria,2TQUB@28211|Alphaproteobacteria,1JR2M@119045|Methylobacteriaceae	28211|Alphaproteobacteria	S	PFAM permease YjgP YjgQ family protein	MA20_28210	-	-	ko:K07091	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
k141_7915_1	1123270.ATUR01000002_gene2354	1.14e-85	258.0	COG0047@1|root,COG0047@2|Bacteria,1MU4Y@1224|Proteobacteria,2TS67@28211|Alphaproteobacteria,2K0NC@204457|Sphingomonadales	204457|Sphingomonadales	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purQ	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase_5
k141_572_1	985054.JQEZ01000002_gene3823	1.85e-14	78.6	COG0810@1|root,COG0810@2|Bacteria,1QW8M@1224|Proteobacteria,2TWSZ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	Domain of unknown function (DUF4173)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4173
k141_3043_1	998674.ATTE01000001_gene3423	6.27e-87	274.0	COG1960@1|root,COG1960@2|Bacteria,1MU20@1224|Proteobacteria,1RNV1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	acyl-CoA dehydrogenase	-	-	-	ko:K20035	ko00920,map00920	-	R11130	RC03363	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_C,Acyl-CoA_dh_M,Acyl-CoA_dh_N,AcylCoA_DH_N
k141_7344_1	406817.XNC1_4455	7.95e-32	115.0	COG3293@1|root,COG3293@2|Bacteria,1RBFK@1224|Proteobacteria,1S22S@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Pfam Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4096
k141_2427_1	159749.K0S2B0	3.36e-29	119.0	2E3BA@1|root,2SAF2@2759|Eukaryota,2XG0Z@2836|Bacillariophyta	2836|Bacillariophyta	S	FG-GAP repeat	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP_2
k141_4278_1	1049564.TevJSym_bd00260	1.51e-61	205.0	COG0247@1|root,COG0247@2|Bacteria,1MWTK@1224|Proteobacteria,1RQ9M@1236|Gammaproteobacteria,1J7KN@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Cysteine-rich domain	glpC	GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0022900,GO:0043167,GO:0043169,GO:0044237,GO:0044464,GO:0045333,GO:0046872,GO:0048037,GO:0051536,GO:0051540,GO:0055114,GO:0071944	1.1.5.3	ko:K00113,ko:K11473	ko00564,ko00630,ko01100,ko01110,ko01120,ko01130,map00564,map00630,map01100,map01110,map01120,map01130	-	R00475,R00848	RC00029,RC00042	ko00000,ko00001,ko01000	-	-	-	CCG,Fer4_8
k141_4891_1	1207063.P24_02626	1.36e-19	87.4	COG0584@1|root,COG0584@2|Bacteria,1MW6Z@1224|Proteobacteria,2V78M@28211|Alphaproteobacteria,2JSGH@204441|Rhodospirillales	204441|Rhodospirillales	C	Glycerophosphoryl diester phosphodiesterase family	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
k141_9147_1	272943.RSP_1913	1.57e-85	255.0	COG2057@1|root,COG2057@2|Bacteria,1RA4V@1224|Proteobacteria,2TQS5@28211|Alphaproteobacteria,1FAXB@1060|Rhodobacter	28211|Alphaproteobacteria	H	TIGRFAM 3-oxoacid CoA-transferase, B subunit	scoB	-	2.8.3.5	ko:K01029	ko00072,ko00280,ko00650,map00072,map00280,map00650	-	R00410	RC00014	ko00000,ko00001,ko01000	-	-	-	CoA_trans
k141_1188_1	1123366.TH3_10246	3.23e-76	252.0	COG1530@1|root,COG1530@2|Bacteria,1MV65@1224|Proteobacteria,2TRX2@28211|Alphaproteobacteria,2JPPJ@204441|Rhodospirillales	204441|Rhodospirillales	J	Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs	rne	-	3.1.26.12	ko:K08300,ko:K08301	ko03018,map03018	M00394	-	-	ko00000,ko00001,ko00002,ko01000,ko03009,ko03019	-	-	-	RNase_E_G,S1
k141_6738_1	998674.ATTE01000001_gene2101	2.9e-91	281.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,1RVXM@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	belongs to the aldehyde dehydrogenase family	-	-	-	ko:K22187	ko00040,map00040	-	R11768	RC00080	ko00000,ko00001,ko01000	-	-	-	Aldedh
k141_6738_2	351016.RAZWK3B_19726	6.53e-40	141.0	COG2355@1|root,COG2355@2|Bacteria,1MWEW@1224|Proteobacteria,2TR5C@28211|Alphaproteobacteria,2P0Z9@2433|Roseobacter	28211|Alphaproteobacteria	E	COG2355 Zn-dependent dipeptidase, microsomal dipeptidase homolog	-	-	3.4.13.19	ko:K01273	-	-	-	-	ko00000,ko00537,ko01000,ko01002,ko04147	-	-	-	Peptidase_M19
k141_7345_1	999541.bgla_1g25490	4.19e-05	45.4	COG0330@1|root,COG0330@2|Bacteria,1MUM8@1224|Proteobacteria,2VHBD@28216|Betaproteobacteria,1K0SQ@119060|Burkholderiaceae	28216|Betaproteobacteria	O	PFAM band 7 protein	qmcA	-	-	-	-	-	-	-	-	-	-	-	Band_7,Band_7_C
k141_7345_2	63737.Npun_R2254	1.65e-30	115.0	COG0637@1|root,COG0637@2|Bacteria,1G7W5@1117|Cyanobacteria,1HQUJ@1161|Nostocales	1117|Cyanobacteria	S	TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
k141_2428_1	585423.KR49_04430	9.38e-37	147.0	COG2931@1|root,COG4932@1|root,COG2931@2|Bacteria,COG4932@2|Bacteria	2|Bacteria	M	domain protein	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Calx-beta,SdrD_B
k141_1814_1	1380394.JADL01000005_gene5357	4.44e-16	74.3	COG1607@1|root,COG1607@2|Bacteria,1MZAZ@1224|Proteobacteria,2U93J@28211|Alphaproteobacteria,2JSPZ@204441|Rhodospirillales	204441|Rhodospirillales	I	Thioesterase superfamily	-	-	-	ko:K10806	ko01040,map01040	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	4HBT
k141_1814_2	754476.Q7A_2225	1.05e-45	164.0	COG0397@1|root,COG0397@2|Bacteria,1MVK3@1224|Proteobacteria,1RNCS@1236|Gammaproteobacteria,45ZY7@72273|Thiotrichales	72273|Thiotrichales	S	Belongs to the UPF0061 (SELO) family	-	-	-	-	-	-	-	-	-	-	-	-	UPF0061
k141_576_1	562970.Btus_2406	2.1e-62	206.0	COG0247@1|root,COG1139@1|root,COG0247@2|Bacteria,COG1139@2|Bacteria,1TREQ@1239|Firmicutes,4H9UI@91061|Bacilli,278ZI@186823|Alicyclobacillaceae	91061|Bacilli	C	Domain of unknown function (DUF3390)	yvfW	-	-	ko:K18929	-	-	-	-	ko00000	-	-	-	DUF3390,Fer4_8,LUD_dom
k141_1190_1	382464.ABSI01000014_gene1479	2.95e-91	288.0	COG2217@1|root,COG2217@2|Bacteria,46S9Z@74201|Verrucomicrobia,2ITMQ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	E1-E2 ATPase	-	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,Hydrolase,YHS
k141_7917_1	281687.CJA31272	9.89e-17	73.9	2EA4H@1|root,2SGDU@2759|Eukaryota,3A53V@33154|Opisthokonta	33154|Opisthokonta	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_1815_1	697282.Mettu_3586	1.14e-53	187.0	COG0642@1|root,COG2205@2|Bacteria,1N17V@1224|Proteobacteria,1RNG1@1236|Gammaproteobacteria,1XF81@135618|Methylococcales	135618|Methylococcales	T	Signal transduction histidine kinase, subgroup 1, dimerisation phosphoacceptor region	-	-	2.7.13.3	ko:K07640	ko01503,ko02020,map01503,map02020	M00447,M00727,M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
k141_1191_1	1270196.JCKI01000007_gene2297	7.5e-23	98.6	COG0405@1|root,COG0405@2|Bacteria,4NF2H@976|Bacteroidetes,1IP46@117747|Sphingobacteriia	976|Bacteroidetes	E	PFAM Gamma-glutamyltranspeptidase	ggt	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
k141_1191_2	269798.CHU_0416	1.28e-26	108.0	COG2304@1|root,COG2319@1|root,COG2885@1|root,COG2304@2|Bacteria,COG2319@2|Bacteria,COG2885@2|Bacteria,4P1CD@976|Bacteroidetes,47U5D@768503|Cytophagia	976|Bacteroidetes	M	OmpA family	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Laminin_G_3,OmpA,VWA
k141_5523_1	1408418.JNJH01000004_gene1996	1.01e-44	153.0	COG3665@1|root,COG3665@2|Bacteria,1N9DM@1224|Proteobacteria,2TU1Z@28211|Alphaproteobacteria,2JSD5@204441|Rhodospirillales	204441|Rhodospirillales	S	Domain of unknown function (DUF1989)	-	-	-	ko:K09967	-	-	-	-	ko00000	-	-	-	DUF1989
k141_7923_1	1229909.NSED_08165	4.29e-133	397.0	COG1048@1|root,arCOG01697@2157|Archaea,41SE6@651137|Thaumarchaeota	651137|Thaumarchaeota	C	aconitate hydratase	-	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
k141_1198_2	1121918.ARWE01000001_gene2159	1.68e-52	177.0	COG1290@1|root,COG1290@2|Bacteria,1MV97@1224|Proteobacteria,42MD6@68525|delta/epsilon subdivisions,2WPA2@28221|Deltaproteobacteria,43TZT@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Cytochrome b(C-terminal)/b6/petD	cbcW	-	-	ko:K00412	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002,ko03029	-	-	-	Cytochrom_B_C,Cytochrom_B_N_2,Cytochrom_C,Cytochrome_B,Cytochrome_CBB3
k141_1822_1	28229.ND2E_0360	1.13e-103	319.0	COG0480@1|root,COG0480@2|Bacteria,1MUCV@1224|Proteobacteria,1RNNJ@1236|Gammaproteobacteria,2Q65E@267889|Colwelliaceae	1236|Gammaproteobacteria	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA2	GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
k141_6136_1	566466.NOR53_2749	7.06e-22	94.0	COG1233@1|root,COG1233@2|Bacteria,1MV2R@1224|Proteobacteria,1RXCF@1236|Gammaproteobacteria,1J80P@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	Q	Q COG1233 Phytoene dehydrogenase and related proteins	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
k141_6136_2	247639.MGP2080_04855	1.52e-56	190.0	COG1233@1|root,COG1233@2|Bacteria,1MV2R@1224|Proteobacteria,1RSGI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	COG1233 Phytoene dehydrogenase and related proteins	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
k141_7354_2	745014.OMB55_00012650	7.45e-11	66.6	COG1894@1|root,COG1894@2|Bacteria,1MV8F@1224|Proteobacteria,1RMUD@1236|Gammaproteobacteria,1J9NX@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	NADH ubiquinone oxidoreductase, NADH-binding (51 kD) subunit	fdsB	-	-	ko:K00124	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001	-	-	-	Complex1_51K,NADH_4Fe-4S,SLBB
k141_5524_1	1461694.ATO9_06435	5.62e-121	358.0	COG3278@1|root,COG3278@2|Bacteria,1MU18@1224|Proteobacteria,2TR2C@28211|Alphaproteobacteria,2PC7Q@252301|Oceanicola	28211|Alphaproteobacteria	O	Cytochrome C and Quinol oxidase polypeptide I	ccoN	GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015672,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0022900,GO:0022904,GO:0034220,GO:0044237,GO:0044464,GO:0045333,GO:0051179,GO:0051234,GO:0055085,GO:0055114,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:1902600	1.9.3.1	ko:K00404	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	COX1
k141_6748_1	391593.RCCS2_04724	1.64e-154	450.0	COG0028@1|root,COG0028@2|Bacteria,1MWUB@1224|Proteobacteria,2TTAQ@28211|Alphaproteobacteria,2P1TC@2433|Roseobacter	28211|Alphaproteobacteria	H	COG0028 Thiamine pyrophosphate-requiring enzymes acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase	xsc	-	2.3.3.15	ko:K03852	ko00430,map00430	-	R05651	RC02903,RC02909	ko00000,ko00001,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
k141_1199_1	1286106.MPL1_07308	7.69e-86	276.0	COG0013@1|root,COG0013@2|Bacteria,1MU9A@1224|Proteobacteria,1RMWZ@1236|Gammaproteobacteria,45ZUH@72273|Thiotrichales	72273|Thiotrichales	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
k141_1199_2	1117319.PSPO_00747	2.18e-10	60.8	COG2137@1|root,COG2137@2|Bacteria,1N6P6@1224|Proteobacteria,1SCMF@1236|Gammaproteobacteria,2Q0J9@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	S	Modulates RecA activity	recX	GO:0003674,GO:0005488,GO:0005515,GO:0006282,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0019219,GO:0019222,GO:0019899,GO:0030234,GO:0031323,GO:0031668,GO:0033554,GO:0043086,GO:0044092,GO:0048583,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051052,GO:0051171,GO:0051716,GO:0060255,GO:0065007,GO:0065009,GO:0071496,GO:0080090,GO:0080134,GO:0080135,GO:0098772,GO:2001020	-	ko:K03565	-	-	-	-	ko00000,ko03400	-	-	-	RecX
k141_9161_1	1151116.Q7S_02085	4.9e-46	159.0	COG0688@1|root,COG0688@2|Bacteria,1MVT4@1224|Proteobacteria,1RN1U@1236|Gammaproteobacteria,3FF5H@34037|Rahnella	1236|Gammaproteobacteria	I	Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily	psd	GO:0003674,GO:0003824,GO:0004609,GO:0006629,GO:0006644,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0071704,GO:0090407,GO:1901576	4.1.1.65	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	M00093	R02055	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	iECNA114_1301.ECNA114_4379,iECSF_1327.ECSF_4049	PS_Dcarbxylase
k141_8563_1	70448.Q0P3F6	2.41e-154	451.0	COG1008@1|root,KOG4845@2759|Eukaryota,37KP8@33090|Viridiplantae,34JA9@3041|Chlorophyta	3041|Chlorophyta	C	Proton-conducting membrane transporter	nad4	-	1.6.5.3	ko:K03881	ko00190,ko01100,ko04714,ko04723,ko05012,map00190,map01100,map04714,map04723,map05012	M00142	R11945	RC00061	ko00000,ko00001,ko00002,ko01000,ko03029	3.D.1.6	-	-	Proton_antipo_M
k141_4287_1	240016.ABIZ01000001_gene844	3.66e-110	322.0	COG2801@1|root,COG2801@2|Bacteria,46V43@74201|Verrucomicrobia	74201|Verrucomicrobia	L	HTH-like domain	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve
k141_2437_1	314262.MED193_06769	4.44e-93	280.0	COG0115@1|root,COG0115@2|Bacteria,1MVB0@1224|Proteobacteria,2U23D@28211|Alphaproteobacteria	28211|Alphaproteobacteria	EH	Branched-chain amino acid aminotransferase 4-amino-4-deoxychorismate lyase	-	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
k141_5526_1	1138822.PL11_00175	2.48e-11	64.7	COG1247@1|root,COG1247@2|Bacteria,1V3V3@1239|Firmicutes,4HHNY@91061|Bacilli,3F70T@33958|Lactobacillaceae	91061|Bacilli	M	Acetyltransferase (GNAT) domain	ywnH	GO:0003674,GO:0003824,GO:0006464,GO:0006473,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564	2.3.1.183	ko:K03823	ko00440,ko01130,map00440,map01130	-	R08871,R08938	RC00004,RC00064	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_1,Acetyltransf_3,Acetyltransf_4
k141_3056_1	471881.PROPEN_01034	3.2e-60	201.0	COG0615@1|root,COG2870@1|root,COG0615@2|Bacteria,COG2870@2|Bacteria,1MV3Z@1224|Proteobacteria,1RMAJ@1236|Gammaproteobacteria,3Z19Y@583|Proteus	1236|Gammaproteobacteria	F	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose	hldE	GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008219,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0012501,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016779,GO:0019200,GO:0033692,GO:0033785,GO:0033786,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046401,GO:0046835,GO:0070566,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509	2.7.1.167,2.7.7.70	ko:K03272,ko:K21344	ko00540,ko01100,map00540,map01100	M00064	R05644,R05646	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	iECH74115_1262.ECH74115_4363,iECSP_1301.ECSP_4025,iECs_1301.ECs3935,iPC815.YPO0654,iZ_1308.Z4405	CTP_transf_like,PfkB
k141_6140_1	765914.ThisiDRAFT_1678	1.4e-38	130.0	COG0093@1|root,COG0093@2|Bacteria,1RCWZ@1224|Proteobacteria,1S3Z3@1236|Gammaproteobacteria,1WY84@135613|Chromatiales	135613|Chromatiales	J	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome	rplN	-	-	ko:K02874	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L14
k141_6140_2	2340.JV46_07280	5.15e-32	114.0	COG0186@1|root,COG0186@2|Bacteria,1MZIK@1224|Proteobacteria,1S8SS@1236|Gammaproteobacteria,1J6GF@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA	rpsQ	GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046677,GO:0050896,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02961	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S17
k141_6140_3	1304275.C41B8_17753	1.78e-14	67.8	COG0255@1|root,COG0255@2|Bacteria,1N6PR@1224|Proteobacteria,1SCBN@1236|Gammaproteobacteria	1236|Gammaproteobacteria	J	Belongs to the universal ribosomal protein uL29 family	rpmC	GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02904	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L29
k141_4904_2	258594.RPA4691	1.78e-42	155.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,2TQR7@28211|Alphaproteobacteria,3JSI9@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	NT	chemotaxis	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal
k141_7928_2	143224.JQMD01000002_gene4115	8.42e-71	221.0	COG0174@1|root,COG0174@2|Bacteria,4NGG2@976|Bacteroidetes,1HXPA@117743|Flavobacteriia	976|Bacteroidetes	E	glutamine synthetase	glnII	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
k141_1202_1	35128.Thapsdraft1676	3.88e-73	225.0	COG0052@1|root,KOG0832@2759|Eukaryota,2XE8D@2836|Bacillariophyta	2836|Bacillariophyta	J	Ribosomal protein S2	-	GO:0000313,GO:0000314,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005761,GO:0005763,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009507,GO:0009536,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0031974,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0070013,GO:0071704,GO:0098798,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	-	-	-	-	-	-	-	-	-	Ribosomal_S2
k141_7358_1	1380391.JIAS01000003_gene1909	6.12e-97	308.0	COG1042@1|root,COG1042@2|Bacteria,1MW98@1224|Proteobacteria,2TR24@28211|Alphaproteobacteria,2JV15@204441|Rhodospirillales	204441|Rhodospirillales	C	CoA binding domain	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_5,CoA_binding_2,Succ_CoA_lig
k141_6752_1	292564.Cyagr_0134	3.61e-29	118.0	COG0014@1|root,COG0014@2|Bacteria,1G1NS@1117|Cyanobacteria,22RYZ@167375|Cyanobium	1117|Cyanobacteria	E	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate	proA	GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114	1.2.1.41	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	M00015	R03313	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
k141_3639_1	159749.K0T686	3.18e-61	217.0	COG2801@1|root,KOG0017@2759|Eukaryota,2XHU4@2836|Bacillariophyta	159749.K0T686|-	L	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_1203_1	394221.Mmar10_0677	6.91e-48	173.0	COG1033@1|root,COG1033@2|Bacteria,1MUE1@1224|Proteobacteria,2TWVC@28211|Alphaproteobacteria,440R8@69657|Hyphomonadaceae	28211|Alphaproteobacteria	S	Sterol-sensing domain of SREBP cleavage-activation	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
k141_5530_1	247633.GP2143_13416	1.37e-83	259.0	COG2262@1|root,COG2262@2|Bacteria,1MUA0@1224|Proteobacteria,1RN7V@1236|Gammaproteobacteria,1J4RK@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0003924,GO:0005488,GO:0005524,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006414,GO:0006417,GO:0006464,GO:0006468,GO:0006518,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006996,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016043,GO:0016310,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0018105,GO:0018193,GO:0018209,GO:0019001,GO:0019222,GO:0019538,GO:0019843,GO:0022411,GO:0030554,GO:0031323,GO:0031326,GO:0032268,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0032790,GO:0032984,GO:0032988,GO:0034248,GO:0034641,GO:0034645,GO:0035639,GO:0036094,GO:0036211,GO:0036289,GO:0043021,GO:0043022,GO:0043023,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051246,GO:0060255,GO:0065007,GO:0071704,GO:0071826,GO:0071840,GO:0072344,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008,GO:2000112	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
k141_9165_1	1121004.ATVC01000078_gene1191	1.36e-40	137.0	COG0718@1|root,COG0718@2|Bacteria,1RGZD@1224|Proteobacteria,2VSJ2@28216|Betaproteobacteria,2KRFE@206351|Neisseriales	206351|Neisseriales	L	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection	ybaB	-	-	ko:K09747	-	-	-	-	ko00000	-	-	-	YbaB_DNA_bd
k141_8050_1	1207063.P24_08444	5.78e-74	239.0	COG0146@1|root,COG0146@2|Bacteria,1QU46@1224|Proteobacteria,2TVYU@28211|Alphaproteobacteria,2JV59@204441|Rhodospirillales	204441|Rhodospirillales	EQ	Hydantoinase B/oxoprolinase	-	-	3.5.2.14	ko:K01474	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydantoinase_B
k141_3743_1	391593.RCCS2_02113	3.46e-94	281.0	COG1560@1|root,COG1560@2|Bacteria,1MVNI@1224|Proteobacteria,2TS2H@28211|Alphaproteobacteria,2P2PF@2433|Roseobacter	28211|Alphaproteobacteria	M	COG1560 Lauroyl myristoyl acyltransferase	msbB	-	2.3.1.241	ko:K02517	ko00540,ko01100,map00540,map01100	M00060	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Lip_A_acyltrans
k141_6829_1	1283300.ATXB01000001_gene1697	7.64e-74	229.0	COG0356@1|root,COG0356@2|Bacteria,1MV87@1224|Proteobacteria,1S0SN@1236|Gammaproteobacteria,1XFZV@135618|Methylococcales	135618|Methylococcales	C	ATP synthase A chain	-	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
k141_6216_1	268739.Nmlp_2092	1.33e-12	73.2	COG0531@1|root,arCOG00009@2157|Archaea,2XT6Y@28890|Euryarchaeota,241EB@183963|Halobacteria	183963|Halobacteria	E	amino acid	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease,AA_permease_2
k141_4979_1	159749.K0R914	6.14e-49	181.0	COG2801@1|root,KOG0017@2759|Eukaryota,2XEDA@2836|Bacillariophyta	159749.K0R914|-	L	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_3134_1	290400.Jann_0583	2.51e-76	237.0	COG0087@1|root,COG0087@2|Bacteria,1MUST@1224|Proteobacteria,2TRHB@28211|Alphaproteobacteria	28211|Alphaproteobacteria	J	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit	rplC	-	-	ko:K02906	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L3
k141_2520_1	522306.CAP2UW1_3192	5.39e-72	234.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,2VHEI@28216|Betaproteobacteria,1KQHG@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
k141_1903_1	467200.ACFA01000069_gene4390	3.38e-07	55.8	COG2340@1|root,COG2340@2|Bacteria,2GNN0@201174|Actinobacteria	201174|Actinobacteria	T	Cysteine-rich secretory protein family	-	-	-	-	-	-	-	-	-	-	-	-	CAP,TerD
k141_7434_1	751994.AGIG01000035_gene357	2.42e-102	315.0	COG0737@1|root,COG0737@2|Bacteria,1MX03@1224|Proteobacteria,1RPX3@1236|Gammaproteobacteria,1J7VQ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	F	5'-nucleotidase, C-terminal domain	soxB	-	-	ko:K17224	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	-	-	-	5_nucleotid_C
k141_9300_1	1380600.AUYN01000009_gene1308	5.38e-52	172.0	COG0382@1|root,COG0382@2|Bacteria,4NM5C@976|Bacteroidetes,1HWRB@117743|Flavobacteriia	976|Bacteroidetes	H	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_8671_1	1116375.VEJY3_04050	5.71e-135	396.0	COG1680@1|root,COG1680@2|Bacteria,1MY01@1224|Proteobacteria,1RNUI@1236|Gammaproteobacteria,1XZIB@135623|Vibrionales	135623|Vibrionales	V	Beta-lactamase	-	-	3.5.2.6	ko:K01467	ko01501,ko02020,map01501,map02020	M00628	R06363	RC01499	ko00000,ko00001,ko00002,ko01000	-	-	-	Beta-lactamase
k141_2521_1	235909.GK1589	1.4e-25	109.0	COG0534@1|root,COG0534@2|Bacteria,1TP5U@1239|Firmicutes,4HA4W@91061|Bacilli,1WEPF@129337|Geobacillus	91061|Bacilli	V	MatE	norM	GO:0003674,GO:0005215,GO:0006810,GO:0006855,GO:0008150,GO:0015238,GO:0015893,GO:0022857,GO:0042221,GO:0042493,GO:0042891,GO:0042895,GO:0046677,GO:0050896,GO:0051179,GO:0051234,GO:0055085	-	ko:K03327	-	-	-	-	ko00000,ko02000	2.A.66.1	-	-	MatE
k141_55_1	159749.E7BWJ8	6.49e-54	170.0	COG0261@1|root,2S7IP@2759|Eukaryota	2759|Eukaryota	J	rRNA binding	rpl21	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009536,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464	-	-	-	-	-	-	-	-	-	-	Ribosomal_L21p
k141_9301_1	240015.ACP_1725	1.36e-56	195.0	COG1215@1|root,COG1215@2|Bacteria,3Y31I@57723|Acidobacteria,2JIKW@204432|Acidobacteriia	204432|Acidobacteriia	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3
k141_4371_1	351016.RAZWK3B_00565	3.55e-48	157.0	COG3415@1|root,COG3415@2|Bacteria,1RM0K@1224|Proteobacteria,2UBBP@28211|Alphaproteobacteria,2P4UD@2433|Roseobacter	28211|Alphaproteobacteria	L	COG3415 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	HTH_29
k141_8672_1	377629.TERTU_1412	5.52e-35	128.0	COG4974@1|root,COG4974@2|Bacteria,1NY1A@1224|Proteobacteria,1RN33@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Transposase	-	-	-	ko:K07484	-	-	-	-	ko00000	-	-	-	DDE_Tnp_IS66,DDE_Tnp_IS66_C,LZ_Tnp_IS66,zf-IS66
k141_6219_1	1380394.JADL01000001_gene2702	1.51e-09	56.2	COG0782@1|root,COG0782@2|Bacteria,1RCXW@1224|Proteobacteria,2U5JU@28211|Alphaproteobacteria,2JS6I@204441|Rhodospirillales	204441|Rhodospirillales	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	-	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
k141_6219_2	504728.K649_08795	4e-08	55.8	COG1522@1|root,COG1522@2|Bacteria,1WN04@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	K	transcriptional regulator	-	-	-	ko:K03719	-	-	-	-	ko00000,ko03000,ko03036	-	-	-	AsnC_trans_reg,HTH_24,HTH_AsnC-type
k141_8053_2	159749.K0RF60	8.16e-18	78.6	28WH7@1|root,2R399@2759|Eukaryota,2XH85@2836|Bacillariophyta	2836|Bacillariophyta	G	Controls the interaction of photosystem II (PSII) cores with the light-harvesting antenna	psbZ	-	-	ko:K02724	ko00195,ko01100,map00195,map01100	-	-	-	ko00000,ko00001,ko00194	-	-	-	Ycf9
k141_56_1	391613.RTM1035_04465	2.21e-44	159.0	COG4591@1|root,COG4591@2|Bacteria,1MVV7@1224|Proteobacteria,2TRBX@28211|Alphaproteobacteria,46QED@74030|Roseovarius	28211|Alphaproteobacteria	M	COG4591 ABC-type transport system, involved in lipoprotein release, permease component	lolC	-	-	ko:K09808	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125	-	-	FtsX,MacB_PCD
k141_3138_1	314270.RB2083_191	2.2e-29	116.0	COG2270@1|root,COG2270@2|Bacteria,1MWXB@1224|Proteobacteria,2TSCV@28211|Alphaproteobacteria,3ZG39@58840|unclassified Rhodobacteraceae	28211|Alphaproteobacteria	S	Permeases of the major facilitator superfamily	MA20_25070	-	-	ko:K06902	ko04138,map04138	-	-	-	ko00000,ko00001,ko02000,ko04131	2.A.1.24,9.A.15.1	-	-	ATG22
k141_6220_1	545697.HMPREF0216_00313	1e-65	216.0	COG1012@1|root,COG1012@2|Bacteria,1TRGK@1239|Firmicutes,2480V@186801|Clostridia,36EKW@31979|Clostridiaceae	186801|Clostridia	C	PFAM Aldehyde dehydrogenase	eutE	-	1.2.1.10,1.2.1.87	ko:K00132,ko:K13922	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	-	R00228,R01172,R09097	RC00004,RC00184,RC01195	ko00000,ko00001,ko01000	-	-	-	Aldedh
k141_1906_1	1144319.PMI16_01965	4.36e-13	69.7	COG0313@1|root,COG0313@2|Bacteria,1MU0E@1224|Proteobacteria,2VHI1@28216|Betaproteobacteria,472SF@75682|Oxalobacteraceae	28216|Betaproteobacteria	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA	rsmI	-	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
k141_8673_1	1348583.ATLH01000031_gene2070	3.55e-11	62.4	COG0457@1|root,COG0457@2|Bacteria,4NH2K@976|Bacteroidetes,1I1JW@117743|Flavobacteriia,1F8PN@104264|Cellulophaga	976|Bacteroidetes	S	TPR repeat	batC	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8
k141_8673_2	616991.JPOO01000003_gene2143	4.1e-65	215.0	COG0457@1|root,COG0457@2|Bacteria,4NERG@976|Bacteroidetes,1HYP9@117743|Flavobacteriia,23GUC@178469|Arenibacter	976|Bacteroidetes	S	Oxygen tolerance	batD	-	-	-	-	-	-	-	-	-	-	-	BatD,TPR_2
k141_4984_1	1207063.P24_03396	1.63e-52	177.0	COG5360@1|root,COG5360@2|Bacteria,1MUJ4@1224|Proteobacteria,2TR5G@28211|Alphaproteobacteria,2JQ9J@204441|Rhodospirillales	204441|Rhodospirillales	S	Heparinase II/III-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Hepar_II_III,Hepar_II_III_N
k141_8054_1	880072.Desac_0027	4.06e-20	94.0	COG0739@1|root,COG0739@2|Bacteria,1NESH@1224|Proteobacteria,42MGB@68525|delta/epsilon subdivisions,2WJ7F@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM Peptidase M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
k141_1907_1	426355.Mrad2831_5856	3.19e-06	54.7	COG1529@1|root,COG1529@2|Bacteria,1MUEA@1224|Proteobacteria,2TQMW@28211|Alphaproteobacteria,1JTKB@119045|Methylobacteriaceae	28211|Alphaproteobacteria	C	Aldehyde oxidase and xanthine dehydrogenase, a b hammerhead	-	-	1.2.5.3	ko:K03520	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
k141_4985_1	420662.Mpe_A0485	5.75e-39	144.0	COG0138@1|root,COG0138@2|Bacteria,1MUDQ@1224|Proteobacteria,2VJPX@28216|Betaproteobacteria,1KJPZ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	F	Bifunctional purine biosynthesis protein PurH	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
k141_3140_1	400682.PAC_15709510	2.19e-52	173.0	COG2096@1|root,2SQFR@2759|Eukaryota,3ANIU@33154|Opisthokonta,3C1SW@33208|Metazoa	33208|Metazoa	S	Cobalamin adenosyltransferase	-	-	2.5.1.17	ko:K00798	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	Cob_adeno_trans
k141_5607_1	172088.AUGA01000006_gene8023	1.07e-41	141.0	COG0640@1|root,COG0640@2|Bacteria,1R9XP@1224|Proteobacteria,2U5PE@28211|Alphaproteobacteria,3JY7B@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	K	Winged helix DNA-binding domain	MA20_23570	-	-	-	-	-	-	-	-	-	-	-	HTH_34
k141_3128_1	1123037.AUDE01000049_gene841	4.75e-17	75.1	2AH5B@1|root,317F2@2|Bacteria,4P8DB@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_4975_1	159749.K0TQC7	2.38e-49	185.0	COG2801@1|root,KOG0017@2759|Eukaryota,2XF4I@2836|Bacillariophyta	159749.K0TQC7|-	L	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_9294_1	754477.Q7C_2159	3.65e-31	115.0	COG1994@1|root,COG1994@2|Bacteria,1NSFF@1224|Proteobacteria,1S4N8@1236|Gammaproteobacteria,460HE@72273|Thiotrichales	72273|Thiotrichales	S	Peptidase M50	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50
k141_9294_2	247634.GPB2148_1456	2.6e-33	120.0	COG0009@1|root,COG0009@2|Bacteria,1MVPM@1224|Proteobacteria,1RNU8@1236|Gammaproteobacteria,1J4HA@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	Belongs to the SUA5 family	yciO	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	-	-	-	-	-	-	-	-	-	Sua5_yciO_yrdC
k141_6212_1	698761.RTCIAT899_CH13400	1.72e-88	270.0	COG0673@1|root,COG0673@2|Bacteria,1MV7C@1224|Proteobacteria,2TQM1@28211|Alphaproteobacteria,4B7T6@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	2-dehydrogenase	idhA	-	1.1.1.18,1.1.1.369	ko:K00010	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	-	R01183,R09951	RC00182	ko00000,ko00001,ko01000	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
k141_6825_1	351348.Maqu_0484	1.12e-46	167.0	COG3071@1|root,COG3071@2|Bacteria,1MU7A@1224|Proteobacteria,1RMRG@1236|Gammaproteobacteria,46647@72275|Alteromonadaceae	1236|Gammaproteobacteria	H	enzyme of heme biosynthesis	hemY	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K02498	-	-	-	-	ko00000	-	-	-	HemY_N,TPR_2
k141_5597_1	83219.PM02_12700	7.46e-120	350.0	COG4663@1|root,COG4663@2|Bacteria,1MUXI@1224|Proteobacteria,2TQVW@28211|Alphaproteobacteria,3ZUZN@60136|Sulfitobacter	28211|Alphaproteobacteria	Q	Bacterial extracellular solute-binding protein, family 7	-	-	-	-	-	-	-	-	-	-	-	-	DctP
k141_664_1	653948.CCA15972	1.96e-67	230.0	COG1678@1|root,KOG1567@2759|Eukaryota	2759|Eukaryota	K	ribonucleoside-diphosphate reductase activity	RNR2	GO:0003674,GO:0003824,GO:0004748,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005829,GO:0005971,GO:0006139,GO:0006213,GO:0006220,GO:0006221,GO:0006240,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009147,GO:0009148,GO:0009165,GO:0009185,GO:0009186,GO:0009189,GO:0009193,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009215,GO:0009216,GO:0009218,GO:0009219,GO:0009221,GO:0009259,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016491,GO:0016725,GO:0016728,GO:0018130,GO:0019438,GO:0019637,GO:0019692,GO:0019693,GO:0032991,GO:0034641,GO:0034654,GO:0042278,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046062,GO:0046131,GO:0046385,GO:0046483,GO:0046704,GO:0051063,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0061731,GO:0071704,GO:0072521,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1902494,GO:1990204	1.17.4.1	ko:K10808	ko00230,ko00240,ko00480,ko00983,ko01100,ko04115,map00230,map00240,map00480,map00983,map01100,map04115	M00053	R02017,R02019,R02024,R08363,R08364,R11893	RC00613,RC01003	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	iMM904.YGR180C,iMM904.YJL026W,iND750.YGR180C,iND750.YJL026W	Ribonuc_red_sm
k141_3130_1	95619.PM1_0218220	1.95e-82	255.0	COG2255@1|root,COG2255@2|Bacteria,1MU38@1224|Proteobacteria,1RNWY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	GO:0000725,GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007154,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009314,GO:0009378,GO:0009411,GO:0009416,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0031668,GO:0032392,GO:0032508,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071496,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
k141_2516_1	1229909.NSED_08185	2.33e-47	153.0	COG2947@1|root,arCOG08640@2157|Archaea,41SK6@651137|Thaumarchaeota	651137|Thaumarchaeota	S	EVE domain	-	-	-	-	-	-	-	-	-	-	-	-	EVE
k141_6826_1	998674.ATTE01000001_gene369	3.58e-82	259.0	COG4108@1|root,COG4108@2|Bacteria,1MU7X@1224|Proteobacteria,1RMFT@1236|Gammaproteobacteria,4605B@72273|Thiotrichales	72273|Thiotrichales	J	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP	prfC	-	-	ko:K02837	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,RF3_C
k141_50_1	522306.CAP2UW1_2267	6.38e-80	249.0	COG2133@1|root,COG2133@2|Bacteria,1MVK5@1224|Proteobacteria,2VIRC@28216|Betaproteobacteria	28216|Betaproteobacteria	G	sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	GSDH,SGL
k141_1286_1	1229909.NSED_02665	2.44e-91	267.0	COG0231@1|root,arCOG04277@2157|Archaea,41SNP@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Functions by promoting the formation of the first peptide bond	eif5a	-	-	ko:K03263	-	-	-	-	ko00000,ko03012	-	-	-	eIF-5a
k141_1286_2	436308.Nmar_0528	2.41e-09	56.2	arCOG08739@1|root,arCOG08739@2157|Archaea,41SN6@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_3741_1	1096930.L284_20735	1.2e-84	259.0	COG3039@1|root,COG3039@2|Bacteria,1MVDK@1224|Proteobacteria,2TS7B@28211|Alphaproteobacteria,2K3KK@204457|Sphingomonadales	204457|Sphingomonadales	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DUF772
k141_8049_1	493475.GARC_1472	6.87e-38	141.0	COG0556@1|root,COG0556@2|Bacteria,1MUFK@1224|Proteobacteria,1RN6Z@1236|Gammaproteobacteria,4645B@72275|Alteromonadaceae	1236|Gammaproteobacteria	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009314,GO:0009380,GO:0009628,GO:0032991,GO:0042802,GO:0044424,GO:0044464,GO:0050896,GO:1902494,GO:1905347,GO:1905348,GO:1990391	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
k141_8049_2	1122164.JHWF01000003_gene2081	1.34e-22	96.3	COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,1RNN0@1236|Gammaproteobacteria,1JD44@118969|Legionellales	118969|Legionellales	E	DegT/DnrJ/EryC1/StrS aminotransferase family	aatA	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
k141_1287_1	305700.B447_19254	1.36e-16	81.3	COG0334@1|root,COG0334@2|Bacteria,1MUMF@1224|Proteobacteria,2VIZ7@28216|Betaproteobacteria,2KUWM@206389|Rhodocyclales	206389|Rhodocyclales	E	Belongs to the Glu Leu Phe Val dehydrogenases family	-	-	1.4.1.3	ko:K00261	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
k141_9297_1	1286106.MPL1_01747	1.36e-142	411.0	COG0192@1|root,COG0192@2|Bacteria,1MUFQ@1224|Proteobacteria,1RNV6@1236|Gammaproteobacteria,45ZZ4@72273|Thiotrichales	72273|Thiotrichales	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	-	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
k141_3132_1	323261.Noc_1604	1.87e-79	264.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1MU7B@1224|Proteobacteria,1RN2W@1236|Gammaproteobacteria,1WWAR@135613|Chromatiales	135613|Chromatiales	E	glutamate synthase	-	-	1.4.1.13,1.4.1.14	ko:K00265	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
k141_3742_1	436308.Nmar_1652	2.05e-99	313.0	COG4257@1|root,arCOG06267@1|root,arCOG03564@2157|Archaea,arCOG06267@2157|Archaea,41S5S@651137|Thaumarchaeota	651137|Thaumarchaeota	V	resistance protein	-	-	-	ko:K14166	-	-	-	-	ko00000,ko02000	-	-	-	CopC,CopD
k141_5600_1	765914.ThisiDRAFT_2023	9.52e-98	295.0	COG0133@1|root,COG0133@2|Bacteria,1MUS8@1224|Proteobacteria,1RP4D@1236|Gammaproteobacteria,1WW9F@135613|Chromatiales	135613|Chromatiales	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB	-	4.2.1.20	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
k141_8107_1	1123514.KB905899_gene842	8.23e-77	251.0	COG0577@1|root,COG0577@2|Bacteria,1MW6D@1224|Proteobacteria,1RN49@1236|Gammaproteobacteria	1236|Gammaproteobacteria	V	COG0577 ABC-type antimicrobial peptide transport system permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
k141_9365_1	6412.HelroP173533	4.48e-15	83.6	KOG1864@1|root,KOG1864@2759|Eukaryota	2759|Eukaryota	O	ubiquitinyl hydrolase activity	-	-	3.4.19.12	ko:K11366,ko:K11850,ko:K11854	-	-	-	-	ko00000,ko01000,ko01002,ko03021,ko03036,ko04121	-	-	-	OTU,UCH,UCH_1
k141_3190_1	187272.Mlg_0224	2.05e-12	65.1	COG3023@1|root,COG3023@2|Bacteria,1RDHU@1224|Proteobacteria,1S3PG@1236|Gammaproteobacteria,1WWUP@135613|Chromatiales	135613|Chromatiales	V	PFAM N-acetylmuramoyl-L-alanine amidase family 2	-	-	3.5.1.28	ko:K03806	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	Amidase_2
k141_3190_2	1279038.KB907342_gene2657	2.62e-18	84.3	COG1385@1|root,COG1385@2|Bacteria,1MXCU@1224|Proteobacteria,2TS0N@28211|Alphaproteobacteria,2JRPI@204441|Rhodospirillales	204441|Rhodospirillales	J	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit	rsmE	-	2.1.1.193	ko:K09761	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_RNA
k141_5663_1	765911.Thivi_2181	1.21e-13	73.9	COG1199@1|root,COG1199@2|Bacteria,1QW37@1224|Proteobacteria,1T2R3@1236|Gammaproteobacteria,1X2NJ@135613|Chromatiales	135613|Chromatiales	KL	ATP-dependent helicase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_1356_1	561231.Pecwa_4095	1.61e-34	135.0	COG1012@1|root,COG1012@2|Bacteria,1QUBI@1224|Proteobacteria,1RP7H@1236|Gammaproteobacteria,1MRRK@122277|Pectobacterium	1236|Gammaproteobacteria	C	Aldehyde dehydrogenase family	pduP	-	1.2.1.87	ko:K04021,ko:K13922	ko00620,ko00640,ko01100,ko01120,map00620,map00640,map01100,map01120	-	R00228,R09097	RC00004,RC00184,RC01195	ko00000,ko00001,ko01000	-	-	iAPECO1_1312.APECO1_2291,iECED1_1282.ECED1_3458	Aldedh
k141_8108_1	1229909.NSED_03235	1.92e-118	341.0	arCOG01781@1|root,arCOG01781@2157|Archaea,41T0U@651137|Thaumarchaeota	651137|Thaumarchaeota	Q	Protein of unknown function (DUF1698)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
k141_3809_1	153948.NAL212_0278	2.49e-64	221.0	COG3459@1|root,COG3459@2|Bacteria,1MVNX@1224|Proteobacteria,2VKDG@28216|Betaproteobacteria,371PE@32003|Nitrosomonadales	28216|Betaproteobacteria	G	Glycosyl hydrolase 36 superfamily, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_36,Glyco_transf_36,Glycoamylase
k141_3191_1	754477.Q7C_2395	2.46e-159	454.0	COG0050@1|root,COG0050@2|Bacteria,1MVC0@1224|Proteobacteria,1RMYX@1236|Gammaproteobacteria,45ZSW@72273|Thiotrichales	72273|Thiotrichales	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
k141_2585_1	1123393.KB891317_gene2439	5.78e-41	143.0	2BX2I@1|root,2Z9KR@2|Bacteria,1MXKC@1224|Proteobacteria,2W0AA@28216|Betaproteobacteria,1KS9S@119069|Hydrogenophilales	119069|Hydrogenophilales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_6287_1	10228.TriadP63021	3.88e-39	144.0	COG0072@1|root,KOG2472@2759|Eukaryota,3A7RT@33154|Opisthokonta,3BXEE@33208|Metazoa	33208|Metazoa	J	phenylalanine--tRNA ligase beta	-	-	-	-	-	-	-	-	-	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
k141_5051_1	595460.RRSWK_01848	4.43e-53	177.0	COG0702@1|root,COG0702@2|Bacteria	2|Bacteria	GM	epimerase	CT0995	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10
k141_9368_1	425104.Ssed_3758	1.44e-108	323.0	COG3303@1|root,COG3303@2|Bacteria,1P8CP@1224|Proteobacteria,1RQGG@1236|Gammaproteobacteria,2QAV3@267890|Shewanellaceae	1236|Gammaproteobacteria	C	Seven times multi-haem cytochrome CxxCH	-	-	1.7.2.6	ko:K10535	ko00910,ko01120,map00910,map01120	M00528,M00804	R10164	RC00383	ko00000,ko00001,ko00002,ko01000	-	-	-	Multi-haem_cyto
k141_3192_2	998088.B565_3017	8.34e-08	53.1	COG0162@1|root,COG0162@2|Bacteria,1MVUQ@1224|Proteobacteria,1RPKC@1236|Gammaproteobacteria,1Y3YK@135624|Aeromonadales	135624|Aeromonadales	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	-	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
k141_6899_1	1229204.AMYY01000010_gene607	1.89e-33	120.0	COG0066@1|root,COG0066@2|Bacteria,1MVXB@1224|Proteobacteria,2TRRS@28211|Alphaproteobacteria,4BQ1T@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuD	-	4.2.1.33,4.2.1.35	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R10170	RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase_C
k141_6899_2	633149.Bresu_3088	3.29e-36	134.0	COG0065@1|root,COG0065@2|Bacteria,1MVYR@1224|Proteobacteria,2TR6K@28211|Alphaproteobacteria,2KF2D@204458|Caulobacterales	204458|Caulobacterales	H	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuC	-	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase
k141_3811_1	572477.Alvin_0439	3.45e-24	97.1	COG2010@1|root,COG2010@2|Bacteria,1NDHN@1224|Proteobacteria,1S700@1236|Gammaproteobacteria,1WYGG@135613|Chromatiales	135613|Chromatiales	C	Planctomycete cytochrome C	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1
k141_8110_1	768671.ThimaDRAFT_4227	3.15e-69	224.0	COG1249@1|root,COG1249@2|Bacteria,1MU2Z@1224|Proteobacteria,1RMC0@1236|Gammaproteobacteria,1WVV8@135613|Chromatiales	135613|Chromatiales	C	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family	-	-	1.8.1.7	ko:K00383	ko00480,ko04918,map00480,map04918	-	R00094,R00115	RC00011	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,Pyr_redox_dim
k141_735_1	1267533.KB906740_gene119	2.63e-24	100.0	COG5485@1|root,COG5485@2|Bacteria	2|Bacteria	S	SnoaL-like polyketide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL
k141_7483_1	1229909.NSED_08290	1.6e-08	52.4	arCOG10587@1|root,arCOG10587@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_7483_2	1229909.NSED_08285	2.38e-62	190.0	arCOG08672@1|root,arCOG08672@2157|Archaea,41SU2@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_1974_1	1216966.BAUC01000026_gene1344	1.89e-35	137.0	COG0046@1|root,COG0047@1|root,COG0046@2|Bacteria,COG0047@2|Bacteria,1MYN4@1224|Proteobacteria,1RMRN@1236|Gammaproteobacteria	1236|Gammaproteobacteria	F	Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate	purL	GO:0000166,GO:0003674,GO:0003824,GO:0004642,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006520,GO:0006541,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009064,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016874,GO:0016879,GO:0016884,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	iECH74115_1262.ECH74115_3792,iECO111_1330.ECO111_3283,iECSP_1301.ECSP_3501,iECs_1301.ECs3423,iG2583_1286.G2583_3088,iJN746.PP_1037,ic_1306.c3080	AIRS_C,GATase_5
k141_4443_1	498211.CJA_3034	2.8e-22	103.0	COG1196@1|root,COG1196@2|Bacteria,1NKHW@1224|Proteobacteria	1224|Proteobacteria	D	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_116_1	616991.JPOO01000003_gene903	2.92e-70	213.0	2EBGV@1|root,335HF@2|Bacteria,4NV5E@976|Bacteroidetes,1I6Q2@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_3813_1	980584.AFPB01000148_gene1469	1.22e-124	360.0	COG1131@1|root,COG1131@2|Bacteria,4NFWM@976|Bacteroidetes,1HXEB@117743|Flavobacteriia	976|Bacteroidetes	V	COG1131 ABC-type multidrug transport system ATPase component	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
k141_737_1	292415.Tbd_2537	1.97e-12	72.8	COG3746@1|root,COG3746@2|Bacteria,1MY3M@1224|Proteobacteria,2VIIP@28216|Betaproteobacteria,1KSJ3@119069|Hydrogenophilales	119069|Hydrogenophilales	P	phosphate-selective porin O and P	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_5668_1	1121875.KB907550_gene675	1.58e-53	177.0	COG3203@1|root,COG3203@2|Bacteria	2|Bacteria	M	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	Alginate_exp,BBP2,Porin_2,Porin_4
k141_117_1	1269813.ATUL01000005_gene1886	3.73e-39	136.0	COG0359@1|root,COG0359@2|Bacteria,1RD0R@1224|Proteobacteria,1S3WS@1236|Gammaproteobacteria,1WYD2@135613|Chromatiales	135613|Chromatiales	J	binds to the 23S rRNA	rplI	-	-	ko:K02939	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L9_C,Ribosomal_L9_N
k141_6290_2	159749.E7BWI8	1.54e-91	272.0	COG0712@1|root,KOG1662@2759|Eukaryota,2XERP@2836|Bacillariophyta	2836|Bacillariophyta	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpD	-	-	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	OSCP
k141_1976_1	391593.RCCS2_10695	1.51e-114	347.0	COG1185@1|root,COG1185@2|Bacteria,1MVB9@1224|Proteobacteria,2TRH3@28211|Alphaproteobacteria,2P1NH@2433|Roseobacter	28211|Alphaproteobacteria	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	GO:0000175,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0004654,GO:0005488,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:0140098,GO:1901360,GO:1901361,GO:1901363,GO:1901575	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
k141_5669_1	317025.Tcr_0917	1.48e-58	195.0	COG1301@1|root,COG1301@2|Bacteria,1MU0Q@1224|Proteobacteria,1RMEN@1236|Gammaproteobacteria,4604B@72273|Thiotrichales	72273|Thiotrichales	C	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family	-	-	-	ko:K03309	-	-	-	-	ko00000	2.A.23	-	-	SDF
k141_3197_1	644107.SL1157_0038	4.28e-103	310.0	COG0683@1|root,COG0683@2|Bacteria,1MUCB@1224|Proteobacteria,2TRWV@28211|Alphaproteobacteria,4NBNG@97050|Ruegeria	28211|Alphaproteobacteria	E	branched-chain amino acid	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6,TAT_signal
k141_8729_1	1123504.JQKD01000046_gene1177	1.56e-59	202.0	COG0370@1|root,COG0370@2|Bacteria,1MUZC@1224|Proteobacteria,2VIRG@28216|Betaproteobacteria,4A9RM@80864|Comamonadaceae	28216|Betaproteobacteria	P	Ferrous iron transport protein B	feoB	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoB_C,FeoB_N,Gate
k141_4444_1	7091.BGIBMGA002632-TA	9.69e-83	273.0	COG0343@1|root,KOG1075@1|root,KOG1075@2759|Eukaryota,KOG3909@2759|Eukaryota,39TZY@33154|Opisthokonta,3BI15@33208|Metazoa,3CYKV@33213|Bilateria,420TT@6656|Arthropoda,3SQX5@50557|Insecta,449FF@7088|Lepidoptera	33208|Metazoa	J	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	2.3.1.15,2.4.2.29	ko:K13506,ko:K15407	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R03789,R09380,R10209	RC00004,RC00039,RC00041,RC00063	ko00000,ko00001,ko00002,ko01000,ko01004,ko03016	-	-	-	Exo_endo_phos_2,RVT_1
k141_6903_1	626887.J057_04075	2.07e-28	110.0	COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,1RMIR@1236|Gammaproteobacteria,465Y3@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	COG0739 Membrane proteins related to metalloendopeptidases	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
k141_6903_2	1454004.AW11_01943	1.11e-44	162.0	COG0653@1|root,COG0653@2|Bacteria,1MUJZ@1224|Proteobacteria,2VHDH@28216|Betaproteobacteria,1KPQR@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	-	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
k141_4445_1	1121033.AUCF01000004_gene5012	1.47e-65	224.0	COG1197@1|root,COG1197@2|Bacteria,1MUXG@1224|Proteobacteria,2TR2H@28211|Alphaproteobacteria,2JPMN@204441|Rhodospirillales	204441|Rhodospirillales	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
k141_1364_1	767434.Fraau_2193	5.69e-13	71.2	COG0489@1|root,COG0489@2|Bacteria,1MU7R@1224|Proteobacteria,1RMJF@1236|Gammaproteobacteria,1X4VI@135614|Xanthomonadales	135614|Xanthomonadales	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	mrp	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	FeS_assembly_P,ParA
k141_2591_1	2340.JV46_05690	5.88e-128	375.0	COG2826@1|root,COG2826@2|Bacteria,1PP49@1224|Proteobacteria,1RN7B@1236|Gammaproteobacteria,1JBRQ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	L	L COG2826 Transposase and inactivated derivatives, IS30 family	insI	GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0004803,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006310,GO:0006313,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0030983,GO:0032135,GO:0032196,GO:0032991,GO:0032993,GO:0034641,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363	-	ko:K07482	-	-	-	-	ko00000	-	-	-	HTH_38,rve
k141_7487_1	159749.E7BWK6	2.79e-87	271.0	COG0464@1|root,KOG0730@2759|Eukaryota	2759|Eukaryota	O	ATP binding	ycf46	-	-	-	-	-	-	-	-	-	-	-	AAA
k141_6292_1	1229909.NSED_08785	4.77e-11	58.5	COG2118@1|root,arCOG04179@2157|Archaea,41SR0@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Belongs to the PDCD5 family	-	-	-	ko:K06875	-	-	-	-	ko00000	-	-	-	dsDNA_bind
k141_6292_2	436308.Nmar_1622	1.94e-212	589.0	COG0604@1|root,arCOG01458@2157|Archaea,41SZ9@651137|Thaumarchaeota	651137|Thaumarchaeota	C	PFAM Alcohol dehydrogenase GroES-like domain	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
k141_5058_1	1121374.KB891591_gene3523	9.97e-114	330.0	COG1183@1|root,COG1183@2|Bacteria,1NC8D@1224|Proteobacteria,1S13Z@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	CDP-alcohol phosphatidyltransferase	-	-	2.7.8.8	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	M00093	R01800	RC00002,RC00017,RC02795	ko00000,ko00001,ko00002,ko01000	-	-	-	CDP-OH_P_transf
k141_2592_1	1049564.TevJSym_bc00190	1.24e-65	211.0	COG1559@1|root,COG1559@2|Bacteria,1MUQF@1224|Proteobacteria,1RMWD@1236|Gammaproteobacteria,1J56S@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation	mltG	GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006807,GO:0008150,GO:0008152,GO:0008932,GO:0008933,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0030203,GO:0030288,GO:0030313,GO:0031224,GO:0031226,GO:0031975,GO:0042597,GO:0043170,GO:0044425,GO:0044459,GO:0044464,GO:0061783,GO:0071704,GO:0071944,GO:1901135,GO:1901564	-	ko:K07082	-	-	-	-	ko00000	-	-	-	YceG
k141_7156_1	940282.CADQ01000012_gene2586	1.08e-14	72.4	COG3039@1|root,COG3039@2|Bacteria,1MVDK@1224|Proteobacteria,2TS7B@28211|Alphaproteobacteria,2JQR2@204441|Rhodospirillales	204441|Rhodospirillales	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DUF772
k141_7722_1	1121271.AUCM01000003_gene1836	7.64e-21	89.7	COG0501@1|root,COG0501@2|Bacteria,1MUV4@1224|Proteobacteria,2TS3N@28211|Alphaproteobacteria	28211|Alphaproteobacteria	O	Belongs to the peptidase M48B family	htpX	-	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	Peptidase_M48
k141_7722_2	391613.RTM1035_06423	5.52e-42	140.0	COG0824@1|root,COG0824@2|Bacteria,1MZB3@1224|Proteobacteria,2U7CU@28211|Alphaproteobacteria,46P54@74030|Roseovarius	28211|Alphaproteobacteria	S	Thioesterase-like superfamily	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT_2
k141_987_1	1207063.P24_07579	5.55e-07	56.6	COG2271@1|root,COG2271@2|Bacteria,1QU9E@1224|Proteobacteria,2TWHH@28211|Alphaproteobacteria,2JR0J@204441|Rhodospirillales	204441|Rhodospirillales	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
k141_1608_1	1408445.JHXP01000038_gene2061	4.36e-48	162.0	COG0388@1|root,COG0388@2|Bacteria,1MUUB@1224|Proteobacteria,1RNVZ@1236|Gammaproteobacteria,1JCNT@118969|Legionellales	118969|Legionellales	S	Carbon-nitrogen hydrolase	ramA	-	-	ko:K11206	-	-	-	-	ko00000,ko01000	-	-	-	CN_hydrolase
k141_1608_2	1033802.SSPSH_001829	1.45e-06	50.4	COG0312@1|root,COG0312@2|Bacteria,1MUSK@1224|Proteobacteria,1RMA5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	'responsible for the proteolytic maturation of the E. coli pMccB17 plasmid-encoded microcin B17, an exported protein that targets the essential topoisomerase II DNA gyrase	tldD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564	-	ko:K03568	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
k141_2232_1	767434.Fraau_0646	6.61e-74	246.0	COG0085@1|root,COG0085@2|Bacteria,1MUC4@1224|Proteobacteria,1RMK0@1236|Gammaproteobacteria,1X3ME@135614|Xanthomonadales	135614|Xanthomonadales	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
k141_2232_2	1118235.CAJH01000065_gene3564	4.55e-39	144.0	COG0086@1|root,COG0086@2|Bacteria,1MU3M@1224|Proteobacteria,1RPYH@1236|Gammaproteobacteria,1X3IQ@135614|Xanthomonadales	135614|Xanthomonadales	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
k141_7723_1	345219.Bcoa_2468	2.32e-56	187.0	COG2896@1|root,COG2896@2|Bacteria,1TP89@1239|Firmicutes,4HAKQ@91061|Bacilli,1ZCD4@1386|Bacillus	91061|Bacilli	H	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate	moaA	-	4.1.99.22	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394	RC03420	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Mob_synth_C,Radical_SAM
k141_5924_1	159749.E7BWL7	1.51e-111	323.0	COG0087@1|root,KOG3141@2759|Eukaryota,2XD8K@2836|Bacillariophyta	2836|Bacillariophyta	J	Belongs to the universal ribosomal protein uL3 family	-	-	-	ko:K02906	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L3
k141_5924_2	159749.E7BWL8	3.92e-55	179.0	COG0088@1|root,KOG1624@2759|Eukaryota	2759|Eukaryota	J	structural constituent of ribosome	rpl4	GO:0000311,GO:0000313,GO:0000315,GO:0003674,GO:0003676,GO:0003723,GO:0003727,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008187,GO:0008266,GO:0009058,GO:0009059,GO:0009507,GO:0009532,GO:0009534,GO:0009535,GO:0009536,GO:0009547,GO:0009570,GO:0009579,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022626,GO:0031976,GO:0031984,GO:0032991,GO:0034357,GO:0034641,GO:0034645,GO:0042651,GO:0043043,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044436,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0055035,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02926	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L4
k141_8355_1	1163617.SCD_n01883	1.59e-83	268.0	COG1148@1|root,COG1908@1|root,COG1148@2|Bacteria,COG1908@2|Bacteria,1MWAG@1224|Proteobacteria,2WEVG@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Methyl-viologen-reducing hydrogenase, delta subunit	-	-	-	ko:K16886	-	-	-	-	ko00000	-	-	-	Fer4,FlpD,Pyr_redox_2
k141_4077_1	414684.RC1_0621	1.41e-66	213.0	COG0275@1|root,COG0275@2|Bacteria,1MUT4@1224|Proteobacteria,2TRQA@28211|Alphaproteobacteria,2JPTV@204441|Rhodospirillales	204441|Rhodospirillales	J	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH	-	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
k141_5315_1	1101189.AQUO01000002_gene733	3.53e-66	213.0	COG2801@1|root,COG2801@2|Bacteria,1MVC8@1224|Proteobacteria,2TRX0@28211|Alphaproteobacteria,2PWUE@265|Paracoccus	28211|Alphaproteobacteria	L	HTH-like domain	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve
k141_6545_1	398580.Dshi_3565	1.87e-24	100.0	COG1364@1|root,COG1364@2|Bacteria,1MU0T@1224|Proteobacteria,2TS98@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate	argJ	GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.3.1.1,2.3.1.35	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259,R02282	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	ArgJ
k141_6545_2	376733.IT41_10515	3.94e-57	179.0	COG0494@1|root,COG0494@2|Bacteria,1RCZM@1224|Proteobacteria,2U7A4@28211|Alphaproteobacteria,2PX71@265|Paracoccus	28211|Alphaproteobacteria	L	NUDIX domain	mutT	GO:0003674,GO:0003824,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	Acetyltransf_3,NUDIX,NUDIX_4
k141_9607_1	1122214.AQWH01000016_gene1589	4.17e-09	54.7	COG2963@1|root,COG2963@2|Bacteria,1RHKX@1224|Proteobacteria,2U9TV@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	COG2963 Transposase and inactivated derivatives	-	-	-	ko:K07483	-	-	-	-	ko00000	-	-	-	HTH_Tnp_1
k141_9607_2	1123360.thalar_02506	9.4e-187	524.0	COG2801@1|root,COG2963@1|root,COG2801@2|Bacteria,COG2963@2|Bacteria,1PBHA@1224|Proteobacteria,2TRQF@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	COG2801 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	HTH_32,rve
k141_3440_1	400668.Mmwyl1_2433	3.33e-32	118.0	COG0121@1|root,COG0121@2|Bacteria,1QJEB@1224|Proteobacteria,1S6PH@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Glutamine amidotransferase	-	-	-	-	-	-	-	-	-	-	-	-	GATase_4
k141_6621_1	391589.RGAI101_2960	4.62e-07	50.8	COG3221@1|root,COG3221@2|Bacteria,1MXD8@1224|Proteobacteria,2TQMQ@28211|Alphaproteobacteria,2P1SH@2433|Roseobacter	28211|Alphaproteobacteria	P	COG3221 ABC-type phosphate phosphonate transport system, periplasmic component	phnD	-	-	ko:K02044	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	Phosphonate-bd
k141_6621_2	1415756.JQMY01000001_gene2893	1.27e-70	219.0	COG3638@1|root,COG3638@2|Bacteria,1MVE9@1224|Proteobacteria,2TRR3@28211|Alphaproteobacteria,2PCWU@252301|Oceanicola	28211|Alphaproteobacteria	P	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system	phnC	GO:0003674,GO:0003824,GO:0005215,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015399,GO:0015405,GO:0015416,GO:0015604,GO:0015605,GO:0015698,GO:0015716,GO:0015748,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0034220,GO:0042623,GO:0042626,GO:0043225,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0098656,GO:0099133	3.6.3.28	ko:K02041	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.9	-	-	ABC_tran
k141_9024_1	1121374.KB891575_gene1581	4.07e-19	92.0	COG0643@1|root,COG2198@1|root,COG0643@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,1RMS6@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	COG0643 Chemotaxis protein histidine kinase and related kinases	chpA	-	-	ko:K02487,ko:K06596	ko02020,ko02025,map02020,map02025	M00507	-	-	ko00000,ko00001,ko00002,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt,Response_reg
k141_9682_1	998674.ATTE01000001_gene3151	1.17e-108	335.0	COG0404@1|root,COG0665@1|root,COG0404@2|Bacteria,COG0665@2|Bacteria,1QV5I@1224|Proteobacteria,1SK44@1236|Gammaproteobacteria,463WS@72273|Thiotrichales	1236|Gammaproteobacteria	E	FAD dependent oxidoreductase central domain	-	-	-	-	-	-	-	-	-	-	-	-	DAO,FAO_M,GCV_T,GCV_T_C
k141_4156_1	1354722.JQLS01000008_gene3139	8.2e-86	254.0	COG1762@1|root,COG1762@2|Bacteria,1RD0E@1224|Proteobacteria,2U7B0@28211|Alphaproteobacteria,46PI0@74030|Roseovarius	28211|Alphaproteobacteria	G	PTS IIA-like nitrogen-regulatory protein PtsN	ptsN	-	-	ko:K02806	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	-	-	-	PTS_EIIA_2
k141_2307_1	504472.Slin_0591	1.51e-39	146.0	COG3828@1|root,COG3828@2|Bacteria,4NFMU@976|Bacteroidetes,47K27@768503|Cytophagia	976|Bacteroidetes	S	Trehalose utilisation	-	-	-	-	-	-	-	-	-	-	-	-	ThuA
k141_2923_1	318586.Pden_4986	1.19e-40	146.0	COG1597@1|root,COG1597@2|Bacteria,1QV26@1224|Proteobacteria,2TVE3@28211|Alphaproteobacteria,2PWTG@265|Paracoccus	28211|Alphaproteobacteria	I	Diacylglycerol kinase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	NAD_kinase
k141_2923_2	426114.THI_0482	2.47e-24	99.0	COG1071@1|root,COG1071@2|Bacteria,1MU5R@1224|Proteobacteria,2VN57@28216|Betaproteobacteria,1KK8N@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Dehydrogenase E1 component	acoA	-	1.2.4.1	ko:K00161,ko:K21416	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh
k141_4157_1	1207063.P24_11335	1.92e-80	255.0	COG0747@1|root,COG0747@2|Bacteria,1MUP8@1224|Proteobacteria,2TQXX@28211|Alphaproteobacteria,2JQIA@204441|Rhodospirillales	204441|Rhodospirillales	E	COG0747 ABC-type dipeptide transport system, periplasmic component	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
k141_4777_1	491915.Aflv_0218	8.61e-14	75.1	COG0010@1|root,COG0010@2|Bacteria,1TP2A@1239|Firmicutes,4HA7S@91061|Bacilli,21WYH@150247|Anoxybacillus	91061|Bacilli	E	Arginase family	-	-	3.5.3.11	ko:K01480	ko00330,ko01100,map00330,map01100	M00133	R01157	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
k141_9026_1	472759.Nhal_3948	3.05e-109	329.0	COG0056@1|root,COG0056@2|Bacteria,1MUG7@1224|Proteobacteria,1RP4V@1236|Gammaproteobacteria,1WVYR@135613|Chromatiales	135613|Chromatiales	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
k141_3501_1	1265503.KB905161_gene3239	2.64e-63	211.0	COG2271@1|root,COG2271@2|Bacteria,1MXUC@1224|Proteobacteria,1RRF8@1236|Gammaproteobacteria,2Q7GP@267889|Colwelliaceae	1236|Gammaproteobacteria	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
k141_7795_1	3847.GLYMA13G11980.1	4.58e-21	99.0	2CUMQ@1|root,2RN4M@2759|Eukaryota,37U2D@33090|Viridiplantae,3GX5D@35493|Streptophyta,4JTXP@91835|fabids	35493|Streptophyta	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_459_2	269796.Rru_A3734	3.08e-45	156.0	COG0008@1|root,COG0008@2|Bacteria,1MUN7@1224|Proteobacteria,2TR2V@28211|Alphaproteobacteria,2JPHU@204441|Rhodospirillales	204441|Rhodospirillales	J	Belongs to the class-I aminoacyl-tRNA synthetase family	gluQ	-	-	ko:K01894	-	-	-	-	ko00000,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1c
k141_5994_1	525897.Dbac_2155	1.07e-06	47.0	COG2721@1|root,COG2721@2|Bacteria,1MZBN@1224|Proteobacteria,42TXF@68525|delta/epsilon subdivisions,2WQVR@28221|Deltaproteobacteria,2MCFF@213115|Desulfovibrionales	28221|Deltaproteobacteria	G	SAF domain	-	-	4.4.1.24	ko:K16845	ko00270,map00270	-	R07633	RC01785	ko00000,ko00001,ko01000	-	-	-	SAF
k141_5994_2	1569209.BBPH01000095_gene1455	2.07e-116	342.0	COG2721@1|root,COG2721@2|Bacteria,1MU9V@1224|Proteobacteria,2TTDT@28211|Alphaproteobacteria,2PV4X@265|Paracoccus	28211|Alphaproteobacteria	G	D-galactarate dehydratase / Altronate hydrolase, C terminus	garD	-	4.2.1.7,4.4.1.24	ko:K16846,ko:K16850	ko00040,ko00270,ko01100,map00040,map00270,map01100	M00631	R01540,R07633	RC00543,RC01785	ko00000,ko00001,ko00002,ko01000	-	-	-	GD_AH_C
k141_9683_1	1121875.KB907546_gene2207	4.61e-286	788.0	COG5476@1|root,COG5476@2|Bacteria,4NG23@976|Bacteroidetes,1I0K5@117743|Flavobacteriia	2|Bacteria	S	MlrC C-terminus	-	-	-	ko:K19048	-	-	-	-	ko00000,ko02048	-	-	-	DUF1485,MlrC_C
k141_3502_2	1037409.BJ6T_06980	1.77e-13	70.1	COG3381@1|root,COG3381@2|Bacteria,1MWWM@1224|Proteobacteria,2TU06@28211|Alphaproteobacteria,3JTAZ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Nitrate reductase delta subunit	torD	-	-	-	-	-	-	-	-	-	-	-	Nitrate_red_del
k141_6625_1	1367847.JCM7686_1946	7.98e-10	59.3	COG0174@1|root,COG0174@2|Bacteria,1MU6V@1224|Proteobacteria,2TRCP@28211|Alphaproteobacteria,2PU10@265|Paracoccus	28211|Alphaproteobacteria	E	Glutamine synthetase, catalytic domain	glnA1	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C
k141_6625_2	305900.GV64_09615	1.28e-49	171.0	COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,1RNW9@1236|Gammaproteobacteria,1XI3H@135619|Oceanospirillales	135619|Oceanospirillales	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.113	ko:K12256	ko00330,ko01100,map00330,map01100	-	R08714	RC00008,RC00062	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_3
k141_7796_2	1415779.JOMH01000001_gene2363	1.13e-26	106.0	COG2020@1|root,COG2020@2|Bacteria,1MWU6@1224|Proteobacteria,1S2PS@1236|Gammaproteobacteria,1X6TI@135614|Xanthomonadales	135614|Xanthomonadales	O	NnrU protein	-	-	-	-	-	-	-	-	-	-	-	-	NnrU
k141_4778_1	1504981.KO116_3212	2.14e-98	301.0	COG3666@1|root,COG3666@2|Bacteria,1N3QR@1224|Proteobacteria,1S01K@1236|Gammaproteobacteria,1XR9F@135619|Oceanospirillales	135619|Oceanospirillales	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DUF772
k141_7239_1	1123393.KB891316_gene2126	5.14e-70	229.0	COG1331@1|root,COG1331@2|Bacteria,1MUUT@1224|Proteobacteria,2VKKI@28216|Betaproteobacteria,1KS50@119069|Hydrogenophilales	119069|Hydrogenophilales	O	Protein of unknown function, DUF255	-	-	-	-	-	-	-	-	-	-	-	-	Thioredox_DsbH
k141_5995_1	891968.Anamo_1626	3.3e-26	110.0	COG1032@1|root,COG1032@2|Bacteria	2|Bacteria	C	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,DUF4070,Radical_SAM
k141_7240_1	3075.A0A087S9Z0	5.73e-46	158.0	COG0356@1|root,KOG4665@2759|Eukaryota,37J5M@33090|Viridiplantae,34IHJ@3041|Chlorophyta	3041|Chlorophyta	C	ATP synthase A chain	-	-	-	ko:K02126	ko00190,ko01100,ko04714,ko05010,ko05012,ko05016,map00190,map01100,map04714,map05010,map05012,map05016	M00158	-	-	ko00000,ko00001,ko00002,ko03029	3.A.2.1	-	-	ATP-synt_A
k141_9029_1	158500.BV97_02944	7.23e-40	145.0	COG3039@1|root,COG3039@2|Bacteria,1MVTU@1224|Proteobacteria,2TVIR@28211|Alphaproteobacteria,2KC5I@204457|Sphingomonadales	204457|Sphingomonadales	L	hmm pf01609	-	-	-	ko:K07481	-	-	-	-	ko00000	-	-	-	-
k141_2312_1	1380367.JIBC01000006_gene302	2.09e-73	235.0	COG5323@1|root,COG5323@2|Bacteria,1MW8S@1224|Proteobacteria,2TREI@28211|Alphaproteobacteria,3ZVEA@60136|Sulfitobacter	28211|Alphaproteobacteria	S	Terminase RNaseH-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Terminase_3,Terminase_6,Terminase_6C
k141_3505_1	1031711.RSPO_c02458	6.01e-69	233.0	COG0188@1|root,COG0188@2|Bacteria,1MUGG@1224|Proteobacteria,2VJ5Q@28216|Betaproteobacteria,1K0UC@119060|Burkholderiaceae	28216|Betaproteobacteria	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
k141_4780_1	1150469.RSPPHO_02404	8.98e-80	261.0	COG0188@1|root,COG0188@2|Bacteria,1MUGG@1224|Proteobacteria,2TSPQ@28211|Alphaproteobacteria,2JPVX@204441|Rhodospirillales	204441|Rhodospirillales	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
k141_463_1	631362.Thi970DRAFT_04435	3.66e-43	154.0	COG0372@1|root,COG0372@2|Bacteria,1MUKX@1224|Proteobacteria,1RS8H@1236|Gammaproteobacteria,1WWVZ@135613|Chromatiales	135613|Chromatiales	C	Belongs to the citrate synthase family	-	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
k141_8442_1	1229909.NSED_00615	4.8e-80	253.0	COG1001@1|root,arCOG00693@2157|Archaea,41SZH@651137|Thaumarchaeota	651137|Thaumarchaeota	F	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family	ade	-	3.5.4.2	ko:K01486	ko00230,ko01100,map00230,map01100	-	R01244	RC00477	ko00000,ko00001,ko01000	-	-	-	Adenine_deam_C,Amidohydro_1
k141_8442_2	1229909.NSED_00610	2.52e-59	183.0	COG1631@1|root,arCOG04109@2157|Archaea,41SQZ@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Binds to the 23S rRNA	rpl44e	-	-	ko:K02929	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L44
k141_9031_1	1123399.AQVE01000031_gene212	3.55e-33	129.0	COG1322@1|root,COG1322@2|Bacteria,1MWHV@1224|Proteobacteria,1RMB8@1236|Gammaproteobacteria,46007@72273|Thiotrichales	72273|Thiotrichales	S	DNA recombination protein RmuC	-	-	-	ko:K09760	-	-	-	-	ko00000	-	-	-	RmuC
k141_4163_1	570952.ATVH01000014_gene2080	8.63e-24	104.0	COG0771@1|root,COG0771@2|Bacteria,1MVYD@1224|Proteobacteria,2TTE8@28211|Alphaproteobacteria,2JP8X@204441|Rhodospirillales	204441|Rhodospirillales	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	IlvN,Mur_ligase_C,Mur_ligase_M
k141_464_1	1370121.AUWS01000006_gene5230	2.16e-10	61.2	COG1680@1|root,COG1680@2|Bacteria,2GK3A@201174|Actinobacteria,235N6@1762|Mycobacteriaceae	201174|Actinobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
k141_464_2	1469245.JFBG01000080_gene297	1.43e-54	182.0	COG4948@1|root,COG4948@2|Bacteria,1MURK@1224|Proteobacteria,1RPIT@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Catalyzes the dehydration of D-galactonate to 2-keto-3- deoxy-D-galactonate	-	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C,MR_MLE_N
k141_1072_1	83406.HDN1F_06760	1.85e-61	200.0	COG0206@1|root,COG0206@2|Bacteria,1MV2X@1224|Proteobacteria,1RPZS@1236|Gammaproteobacteria,1J5BU@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0022607,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034622,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043933,GO:0044085,GO:0044424,GO:0044464,GO:0051258,GO:0051301,GO:0065003,GO:0071840,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
k141_9032_1	187272.Mlg_0335	5.53e-54	180.0	COG0123@1|root,COG0123@2|Bacteria,1MU7P@1224|Proteobacteria,1RN8W@1236|Gammaproteobacteria,1WXNB@135613|Chromatiales	135613|Chromatiales	BQ	PFAM Histone deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Hist_deacetyl
k141_3507_1	1449076.JOOE01000002_gene1170	0.000285	42.4	COG0756@1|root,COG0756@2|Bacteria,1RA7P@1224|Proteobacteria,2U7B5@28211|Alphaproteobacteria,2K4E7@204457|Sphingomonadales	204457|Sphingomonadales	F	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA	dut	-	3.6.1.23	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	M00053	R02100,R11896	RC00002	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	dUTPase
k141_3507_2	991905.SL003B_2352	5.44e-12	68.2	COG0187@1|root,COG0187@2|Bacteria,1MVH1@1224|Proteobacteria,2TQZV@28211|Alphaproteobacteria,4BPE0@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	L	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule	parE	-	-	ko:K02622	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
k141_8444_2	1121015.N789_00780	4.65e-10	60.1	COG0498@1|root,COG0498@2|Bacteria,1MUWQ@1224|Proteobacteria,1RQ0H@1236|Gammaproteobacteria,1X541@135614|Xanthomonadales	135614|Xanthomonadales	E	Threonine synthase	thrC	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP,Thr_synth_N
k141_4165_1	1469613.JT55_15430	1.19e-108	320.0	COG2433@1|root,COG2433@2|Bacteria,1RJ1Q@1224|Proteobacteria,2U9U2@28211|Alphaproteobacteria,3FEBY@34008|Rhodovulum	28211|Alphaproteobacteria	S	IS66 C-terminal element	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS66,DDE_Tnp_IS66_C,LZ_Tnp_IS66,zf-IS66
k141_1074_1	1342299.Z947_2793	5.3e-74	242.0	COG0784@1|root,COG4191@1|root,COG0784@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2TQQ9@28211|Alphaproteobacteria,3ZVXR@60136|Sulfitobacter	28211|Alphaproteobacteria	T	His Kinase A (phosphoacceptor) domain	cckA	-	2.7.13.3	ko:K13587	ko02020,ko04112,map02020,map04112	M00512	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,PAS,PAS_4,PAS_8,PAS_9,Response_reg
k141_8445_1	748247.AZKH_p0152	1.14e-70	233.0	COG0145@1|root,COG0145@2|Bacteria,1MU2Y@1224|Proteobacteria,2W359@28216|Betaproteobacteria	28216|Betaproteobacteria	EQ	Hydantoinase/oxoprolinase N-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	Hydant_A_N,Hydantoinase_A
k141_1242_1	71139.XP_010068635.1	1.61e-12	74.3	COG2801@1|root,KOG0017@2759|Eukaryota,37RIF@33090|Viridiplantae	33090|Viridiplantae	O	Cysteine-rich RLK (RECEPTOR-like protein kinase) 8	-	-	-	-	-	-	-	-	-	-	-	-	RVT_2,Retrotran_gag_2,Retrotran_gag_3,gag_pre-integrs,rve
k141_6794_1	391589.RGAI101_1653	1.69e-123	364.0	COG4584@1|root,COG4584@2|Bacteria,1MWIV@1224|Proteobacteria,2TQKF@28211|Alphaproteobacteria,2P1WD@2433|Roseobacter	28211|Alphaproteobacteria	L	COG4584 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	rve
k141_1859_1	413404.Rmag_0037	1.3e-46	159.0	COG1845@1|root,COG1845@2|Bacteria,1MUCK@1224|Proteobacteria,1RN9D@1236|Gammaproteobacteria,1J4UE@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3	coxC	-	1.9.3.1	ko:K02276	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.6	-	-	COX3
k141_1859_2	1384056.N787_06945	6.43e-11	61.2	COG3175@1|root,COG3175@2|Bacteria,1RDTU@1224|Proteobacteria,1S5XA@1236|Gammaproteobacteria,1X5Z6@135614|Xanthomonadales	135614|Xanthomonadales	O	cytochrome c oxidase assembly protein	cox11	-	-	ko:K02258	ko00190,ko01100,ko04714,map00190,map01100,map04714	M00154	-	-	ko00000,ko00001,ko00002,ko03029	3.D.4.8	-	-	CtaG_Cox11
k141_4327_1	95619.PM1_0201695	2.45e-115	345.0	COG2987@1|root,COG2987@2|Bacteria,1MU4W@1224|Proteobacteria,1RP89@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate	hutU	-	4.2.1.49	ko:K01712	ko00340,ko01100,map00340,map01100	M00045	R02914	RC00804	ko00000,ko00001,ko00002,ko01000	-	-	-	Urocanase,Urocanase_C,Urocanase_N
k141_3710_1	460265.Mnod_7407	3.39e-72	240.0	COG0466@1|root,COG0466@2|Bacteria,1MUV2@1224|Proteobacteria,2TR4E@28211|Alphaproteobacteria,1JR4X@119045|Methylobacteriaceae	28211|Alphaproteobacteria	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
k141_9_1	767817.Desgi_0556	2.1e-49	170.0	COG0517@1|root,COG0517@2|Bacteria,1TQ4J@1239|Firmicutes,24B68@186801|Clostridia,260BK@186807|Peptococcaceae	186801|Clostridia	S	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	Y2_Tnp,Zn_Tnp_IS91
k141_8023_1	1049564.TevJSym_bh00140	1.53e-39	139.0	COG0714@1|root,COG0714@2|Bacteria,1MUFN@1224|Proteobacteria,1RN5G@1236|Gammaproteobacteria,1J4N9@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	COG0714 MoxR-like ATPases	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
k141_8023_2	1049564.TevJSym_bh00130	2.4e-53	176.0	COG1721@1|root,COG1721@2|Bacteria,1Q7RR@1224|Proteobacteria,1RNNP@1236|Gammaproteobacteria,1J5XC@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	conserved protein (some members contain a von Willebrand factor type A (vWA) domain)	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
k141_624_1	999611.KI421504_gene945	4.78e-26	102.0	COG0410@1|root,COG0410@2|Bacteria,1MVVC@1224|Proteobacteria,2TT8N@28211|Alphaproteobacteria,27ZGN@191028|Leisingera	28211|Alphaproteobacteria	E	ABC transporter	livF1	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
k141_624_2	1123501.KB902298_gene3647	1.2e-37	135.0	2E2MA@1|root,32XQG@2|Bacteria,1N2RU@1224|Proteobacteria,2UE7B@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_3095_1	545264.KB898744_gene2063	7.97e-68	218.0	COG0126@1|root,COG0126@2|Bacteria,1MUNU@1224|Proteobacteria,1RMUQ@1236|Gammaproteobacteria,1WX6Z@135613|Chromatiales	135613|Chromatiales	F	Belongs to the phosphoglycerate kinase family	pgk	-	2.7.2.3	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01512	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
k141_3095_2	312153.Pnuc_1816	1.58e-13	70.9	COG0469@1|root,COG0469@2|Bacteria,1MU21@1224|Proteobacteria,2VHN5@28216|Betaproteobacteria,1K3DK@119060|Burkholderiaceae	28216|Betaproteobacteria	G	Belongs to the pyruvate kinase family	pykA	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PK,PK_C
k141_7409_1	765914.ThisiDRAFT_1039	5.45e-60	204.0	COG0568@1|root,COG0568@2|Bacteria,1MVNJ@1224|Proteobacteria,1RMQI@1236|Gammaproteobacteria,1WWD1@135613|Chromatiales	135613|Chromatiales	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	rpoD	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_ner,Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
k141_9259_1	1117647.M5M_18620	2.78e-92	278.0	COG0010@1|root,COG0010@2|Bacteria,1MVFH@1224|Proteobacteria,1RMH5@1236|Gammaproteobacteria,1J4M3@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	E	Belongs to the arginase family	speB	-	3.5.3.11,3.5.3.7,3.5.3.8	ko:K01479,ko:K01480,ko:K12255	ko00330,ko00340,ko01100,map00330,map00340,map01100	M00045,M00133	R01157,R01990,R02285	RC00024,RC00221,RC00329,RC00681	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
k141_1861_1	382464.ABSI01000020_gene286	2.06e-96	301.0	COG1529@1|root,COG1529@2|Bacteria	2|Bacteria	C	xanthine dehydrogenase activity	-	-	1.3.99.16	ko:K07303	-	-	-	-	ko00000,ko01000	-	-	-	Ald_Xan_dh_C2
k141_5564_1	159749.E7BWK8	1.32e-79	262.0	COG0542@1|root,KOG1051@2759|Eukaryota,2XEW9@2836|Bacillariophyta	2836|Bacillariophyta	O	Belongs to the ClpA ClpB family	-	-	-	-	-	-	-	-	-	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
k141_4948_1	697282.Mettu_3066	1.39e-47	162.0	COG2518@1|root,COG2518@2|Bacteria,1MXQC@1224|Proteobacteria,1S2WI@1236|Gammaproteobacteria,1XEYK@135618|Methylococcales	135618|Methylococcales	O	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	-	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
k141_11_1	161156.JQKW01000007_gene624	3.99e-08	57.4	COG1522@1|root,COG1522@2|Bacteria,2GGYH@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	K	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	HTH_AsnC-type
k141_11_2	285535.JOEY01000097_gene3184	8.77e-13	65.1	COG0318@1|root,COG0318@2|Bacteria,2GIUC@201174|Actinobacteria	201174|Actinobacteria	IQ	PFAM AMP-dependent synthetase and ligase	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
k141_2482_1	566466.NOR53_3441	2.34e-73	235.0	COG3666@1|root,COG3666@2|Bacteria,1N3QR@1224|Proteobacteria,1S01K@1236|Gammaproteobacteria,1J7W3@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	L	L COG3666 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_6,DUF772
k141_1862_1	247633.GP2143_14621	6.24e-23	102.0	COG0183@1|root,COG0183@2|Bacteria,1MVPC@1224|Proteobacteria,1S3XA@1236|Gammaproteobacteria,1J7WA@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	I	COG0183 Acetyl-CoA acetyltransferase	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	-
k141_6179_1	1121939.L861_10150	4.61e-21	90.9	COG0517@1|root,COG0517@2|Bacteria,1QV5F@1224|Proteobacteria,1S8MF@1236|Gammaproteobacteria,1XRFN@135619|Oceanospirillales	135619|Oceanospirillales	S	BON domain	-	-	-	-	-	-	-	-	-	-	-	-	BON,CBS
k141_6179_2	93220.LV28_04600	4.61e-07	51.2	COG1652@1|root,COG1652@2|Bacteria,1RD8K@1224|Proteobacteria,2VR7C@28216|Betaproteobacteria,1K875@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Peptidoglycan-binding LysM	ygaU	-	-	-	-	-	-	-	-	-	-	-	BON,LysM
k141_1307_1	1229909.NSED_08340	3.4e-73	233.0	COG0031@1|root,COG0607@1|root,arCOG01430@2157|Archaea,arCOG02021@2157|Archaea,41SYY@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Pyridoxal-phosphate dependent enzyme	-	-	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
k141_5004_1	436308.Nmar_1790	1.34e-138	402.0	COG0174@1|root,arCOG01909@2157|Archaea,41SD6@651137|Thaumarchaeota	651137|Thaumarchaeota	E	TIGRFAM glutamine synthetase, type I	-	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
k141_2540_2	313603.FB2170_06770	5.03e-52	181.0	COG0209@1|root,COG0209@2|Bacteria,4NEHQ@976|Bacteroidetes,1HXGF@117743|Flavobacteriia	976|Bacteroidetes	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	nrd	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_lgC,Ribonuc_red_lgN
k141_2541_1	1238182.C882_3364	2.05e-120	363.0	COG4666@1|root,COG4666@2|Bacteria,1MUNB@1224|Proteobacteria,2TQY9@28211|Alphaproteobacteria,2JQKH@204441|Rhodospirillales	204441|Rhodospirillales	S	Tripartite ATP-independent periplasmic transporter, DctM component	-	-	-	-	-	-	-	-	-	-	-	-	DUF3394,DctM
k141_8690_2	926569.ANT_25720	3.45e-48	162.0	COG4555@1|root,COG4555@2|Bacteria	2|Bacteria	CP	ABC transporter	natA	-	3.6.3.7	ko:K09697	ko02010,ko02020,map02010,map02020	M00253	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.115	-	iYO844.BSU02750	ABC_tran
k141_5626_1	159749.E7BWK4	2.52e-212	589.0	28IP8@1|root,2QR09@2759|Eukaryota,2XF0J@2836|Bacillariophyta	2836|Bacillariophyta	C	Photosynthetic reaction centre protein	psbA	-	1.10.3.9	ko:K02703	ko00195,ko01100,map00195,map01100	M00161	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	-	-	-	Photo_RC
k141_6852_1	1229909.NSED_00360	2.24e-125	366.0	COG0436@1|root,arCOG01131@2157|Archaea,41S8G@651137|Thaumarchaeota	651137|Thaumarchaeota	E	DegT/DnrJ/EryC1/StrS aminotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
k141_6852_2	436308.Nmar_0176	3.39e-07	50.1	arCOG10518@1|root,arCOG10518@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_4395_1	396588.Tgr7_0343	1.32e-23	90.1	2E4KB@1|root,32ZFA@2|Bacteria,1N6R9@1224|Proteobacteria,1SFP8@1236|Gammaproteobacteria,1WZH8@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_4395_2	1158756.AQXQ01000012_gene1996	4.61e-65	202.0	COG1047@1|root,COG1047@2|Bacteria,1REQ1@1224|Proteobacteria,1S2MS@1236|Gammaproteobacteria,1WY6J@135613|Chromatiales	135613|Chromatiales	O	Peptidyl-prolyl cis-trans	-	-	5.2.1.8	ko:K03775	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	-
k141_3769_1	384765.SIAM614_02581	2.58e-214	605.0	COG3653@1|root,COG3653@2|Bacteria,1MWWY@1224|Proteobacteria,2TT5E@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	COG3653 N-acyl-D-aspartate D-glutamate deacylase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
k141_9327_1	1229909.NSED_01660	5.29e-27	105.0	arCOG08643@1|root,arCOG08716@1|root,arCOG08643@2157|Archaea,arCOG08716@2157|Archaea,41T3H@651137|Thaumarchaeota	651137|Thaumarchaeota	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_9327_2	436308.Nmar_0344	1.16e-38	137.0	arCOG08643@1|root,arCOG08643@2157|Archaea,41T2H@651137|Thaumarchaeota	651137|Thaumarchaeota	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_8691_1	519989.ECTPHS_00370	1.8e-100	300.0	COG1600@1|root,COG1600@2|Bacteria,1MV1H@1224|Proteobacteria,1RMD9@1236|Gammaproteobacteria,1WWZ4@135613|Chromatiales	135613|Chromatiales	C	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)	queG	-	1.17.99.6	ko:K18979	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF1730,Fer4_16
k141_7452_1	1238182.C882_2045	1.38e-54	176.0	COG5501@1|root,COG5501@2|Bacteria,1RH4J@1224|Proteobacteria,2U72E@28211|Alphaproteobacteria,2JTAQ@204441|Rhodospirillales	204441|Rhodospirillales	S	sulfur oxidation protein (SoxY)	-	-	-	ko:K17226	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	-	-	-	SoxY
k141_6853_1	384765.SIAM614_23397	6.7e-99	295.0	COG0798@1|root,COG0798@2|Bacteria,1MUXY@1224|Proteobacteria,2TSVJ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	COG0798 Arsenite efflux pump ACR3 and related permeases	arsB	-	-	ko:K03325	-	-	-	-	ko00000,ko02000	2.A.59	-	-	SBF
k141_5627_1	1430440.MGMSRv2_1684	3.24e-104	315.0	COG0114@1|root,COG0114@2|Bacteria,1MUQI@1224|Proteobacteria,2TQM7@28211|Alphaproteobacteria,2JP9U@204441|Rhodospirillales	204441|Rhodospirillales	C	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate	fumC	-	4.2.1.2	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	M00009,M00011,M00173,M00376	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	FumaraseC_C,Lyase_1
k141_2543_1	391589.RGAI101_391	9.23e-120	346.0	COG1484@1|root,COG1484@2|Bacteria,1MWQX@1224|Proteobacteria,2TS16@28211|Alphaproteobacteria,2P2TI@2433|Roseobacter	28211|Alphaproteobacteria	L	COG1484 DNA replication protein	-	-	-	-	-	-	-	-	-	-	-	-	IstB_IS21
k141_8073_1	631362.Thi970DRAFT_02962	2.91e-13	69.7	COG0578@1|root,COG0578@2|Bacteria,1MUMY@1224|Proteobacteria,1RMGP@1236|Gammaproteobacteria,1WXTF@135613|Chromatiales	135613|Chromatiales	C	PFAM FAD dependent oxidoreductase	-	-	1.1.3.21,1.1.5.3	ko:K00105,ko:K00111	ko00564,ko01110,map00564,map01110	-	R00846,R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	DAO,DAO_C
k141_8073_2	1469245.JFBG01000044_gene1866	8.45e-39	131.0	COG5477@1|root,COG5477@2|Bacteria,1N7WT@1224|Proteobacteria,1SETA@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Predicted small integral membrane protein (DUF2160)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2160
k141_9328_1	1121405.dsmv_3368	4.65e-06	48.1	COG0069@1|root,COG2218@1|root,COG0069@2|Bacteria,COG2218@2|Bacteria,1MU7B@1224|Proteobacteria,42MF7@68525|delta/epsilon subdivisions,2WJJR@28221|Deltaproteobacteria,2MICM@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Conserved region in glutamate synthase	-	-	2.1.1.21	ko:K22083	ko00680,ko01120,map00680,map01120	-	R01586	RC00554	ko00000,ko00001,ko01000	-	-	-	Fer4,Fer4_10,Fer4_7,Fer4_9,GXGXG,Glu_syn_central,Glu_synthase
k141_9328_2	1380391.JIAS01000017_gene710	3.82e-63	206.0	COG0174@1|root,COG0174@2|Bacteria,1MUGQ@1224|Proteobacteria,2TTWE@28211|Alphaproteobacteria,2JRBD@204441|Rhodospirillales	204441|Rhodospirillales	E	Glutamine synthetase, catalytic domain	-	-	6.3.4.12	ko:K01949	-	-	-	-	ko00000,ko01000	-	-	-	Gln-synt_C
k141_8692_2	411154.GFO_3002	6.92e-21	92.0	COG1228@1|root,COG1228@2|Bacteria,4NGGD@976|Bacteroidetes,1I07B@117743|Flavobacteriia	976|Bacteroidetes	Q	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,SnoaL_2
k141_3771_1	1249997.JHZW01000003_gene3107	9.53e-97	298.0	COG1132@1|root,COG1132@2|Bacteria,4NE2D@976|Bacteroidetes,1HWWR@117743|Flavobacteriia,2PGCB@252356|Maribacter	976|Bacteroidetes	V	ABC transporter transmembrane region	msbA	-	-	ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106	-	-	ABC_membrane,ABC_tran
k141_5009_1	985054.JQEZ01000002_gene3273	1.13e-78	240.0	COG2326@1|root,COG2326@2|Bacteria,1MVE2@1224|Proteobacteria,2TSU8@28211|Alphaproteobacteria,4N9U1@97050|Ruegeria	28211|Alphaproteobacteria	S	Polyphosphate kinase 2 (PPK2)	ppk2	GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008976,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0044237	2.7.4.1	ko:K22468	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PPK2
k141_5628_1	1123278.KB893597_gene2713	3.44e-31	122.0	COG1609@1|root,COG1609@2|Bacteria,4NDW6@976|Bacteroidetes,47ME3@768503|Cytophagia	976|Bacteroidetes	K	PFAM Periplasmic binding protein LacI transcriptional regulator	-	-	-	ko:K02529,ko:K05499	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_1,Peripla_BP_3
k141_2544_1	1469245.JFBG01000014_gene2042	9.02e-97	292.0	COG1173@1|root,COG1173@2|Bacteria,1MUG0@1224|Proteobacteria,1RN08@1236|Gammaproteobacteria,1X2PA@135613|Chromatiales	1236|Gammaproteobacteria	EP	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
k141_1932_1	1120998.AUFC01000051_gene568	5.26e-13	63.9	2DQE0@1|root,33689@2|Bacteria,1VH8J@1239|Firmicutes,24WJ6@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_3772_1	35128.Thapsdraft2050	1.34e-51	182.0	COG0086@1|root,2RUNH@2759|Eukaryota,2XF5V@2836|Bacillariophyta	2836|Bacillariophyta	H	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC2	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009536,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464	-	-	-	-	-	-	-	-	-	-	RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
k141_3159_1	1002340.AFCF01000025_gene987	2.55e-101	302.0	COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,2TQMJ@28211|Alphaproteobacteria,34F90@302485|Phaeobacter	28211|Alphaproteobacteria	E	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system	potA	-	-	ko:K02052	ko02024,map02024	M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11	-	-	ABC_tran,TOBE_2
k141_7454_1	580332.Slit_1715	4.42e-150	437.0	COG1053@1|root,COG1053@2|Bacteria,1NZBR@1224|Proteobacteria,2VHJ5@28216|Betaproteobacteria,44WIW@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Fumarate reductase flavoprotein C-term	-	-	1.8.99.2	ko:K00394	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00596	R00860,R04927,R08553	RC00007,RC01239,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
k141_3773_1	326442.PSHAb0486	7.97e-27	114.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,2Q46H@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	V	AcrB/AcrD/AcrF family	-	-	-	ko:K18138	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
k141_78_1	159749.E7BWD2	4.21e-186	538.0	COG0086@1|root,2RUNJ@2759|Eukaryota,2XENN@2836|Bacillariophyta	2836|Bacillariophyta	H	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	-	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009536,GO:0030880,GO:0032991,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0061695,GO:1902494,GO:1990234	-	-	-	-	-	-	-	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3
k141_78_2	35128.Thapsdraft1267	3.78e-282	810.0	COG0085@1|root,KOG0214@2759|Eukaryota,2XEM3@2836|Bacillariophyta	2836|Bacillariophyta	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	-	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009536,GO:0030880,GO:0032991,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0061695,GO:1902494,GO:1990234	-	-	-	-	-	-	-	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
k141_9331_1	887898.HMPREF0551_1193	8.83e-54	182.0	COG4992@1|root,COG4992@2|Bacteria,1MV3C@1224|Proteobacteria,2VHEB@28216|Betaproteobacteria,1K4TY@119060|Burkholderiaceae	28216|Betaproteobacteria	E	Aminotransferase	argD	-	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
k141_1316_1	83406.HDN1F_28520	1.26e-19	93.6	COG2937@1|root,COG2937@2|Bacteria,1MWZ6@1224|Proteobacteria,1RM7K@1236|Gammaproteobacteria,1J527@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	I	Belongs to the GPAT DAPAT family	plsB	GO:0003674,GO:0003824,GO:0004366,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006082,GO:0006629,GO:0006631,GO:0006644,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008374,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016020,GO:0016021,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0019752,GO:0031224,GO:0031226,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0071704,GO:0071944,GO:0090407,GO:1901576	2.3.1.15	ko:K00631	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	iECs_1301.ECs5024,iG2583_1286.G2583_4866	Acyltransferase
k141_1934_1	1287276.X752_06515	4.68e-66	213.0	COG4603@1|root,COG4603@2|Bacteria,1MX6V@1224|Proteobacteria,2TUGD@28211|Alphaproteobacteria,43GW8@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
k141_6858_1	1504981.KO116_3985	2.9e-13	69.3	COG1109@1|root,COG1109@2|Bacteria,1MU24@1224|Proteobacteria,1RMR2@1236|Gammaproteobacteria,1XH2Q@135619|Oceanospirillales	135619|Oceanospirillales	G	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate	glmM	-	5.4.2.10	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	-	R02060	RC00408	ko00000,ko00001,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
k141_6858_2	435908.IDSA_02105	1.64e-40	142.0	COG0294@1|root,COG0294@2|Bacteria,1MUIR@1224|Proteobacteria,1RM8G@1236|Gammaproteobacteria,2QF19@267893|Idiomarinaceae	1236|Gammaproteobacteria	H	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives	folP	GO:0003674,GO:0003824,GO:0004156,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042221,GO:0042364,GO:0042398,GO:0042493,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0046655,GO:0046656,GO:0050896,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.15	ko:K00796	ko00790,ko01100,map00790,map01100	M00126,M00841	R03066,R03067	RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	iECO103_1326.ECO103_3924,iPC815.YPO3501	Pterin_bind
k141_7455_1	314345.SPV1_00857	1.15e-71	231.0	COG2270@1|root,COG2270@2|Bacteria,1MWXB@1224|Proteobacteria	1224|Proteobacteria	S	Major facilitator Superfamily	MA20_25070	-	-	ko:K06902	ko04138,map04138	-	-	-	ko00000,ko00001,ko02000,ko04131	2.A.1.24,9.A.15.1	-	-	ATG22
k141_5013_1	1415756.JQMY01000001_gene924	5.33e-20	93.2	COG0665@1|root,COG0665@2|Bacteria,1MVM6@1224|Proteobacteria,2TRM7@28211|Alphaproteobacteria,2PDPC@252301|Oceanicola	28211|Alphaproteobacteria	E	COG0665 Glycine D-amino acid oxidases (deaminating)	-	-	1.5.3.1	ko:K00303	ko00260,ko01100,map00260,map01100	-	R00610	RC00060,RC00557	ko00000,ko00001,ko01000	-	-	-	DAO
k141_3162_1	159749.K0TMA8	1.17e-19	93.2	COG0563@1|root,KOG3078@2759|Eukaryota	2759|Eukaryota	F	adenylate kinase activity	-	-	2.7.4.3,2.7.4.6	ko:K18533,ko:K19788	ko00230,ko00240,ko01100,ko01110,ko01130,map00230,map00240,map01100,map01110,map01130	M00049,M00052,M00053	R00124,R00127,R00156,R00330,R00570,R00722,R01137,R01547,R01857,R02093,R02326,R02331,R03530	RC00002	ko00000,ko00001,ko00002,ko01000,ko03036	-	-	-	ADK,DUF1995,YchF-GTPase_C
k141_2549_1	932213.SPM24T3_20629	7.46e-36	131.0	COG0566@1|root,COG0566@2|Bacteria,1MWBE@1224|Proteobacteria,1RMPR@1236|Gammaproteobacteria,3ZZPZ@613|Serratia	1236|Gammaproteobacteria	J	Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA	trmH	GO:0001510,GO:0002128,GO:0002938,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008175,GO:0008757,GO:0009020,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0106050,GO:0140098,GO:0140101,GO:1901360	2.1.1.34	ko:K00556	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylas_C,SpoU_methylase
k141_9334_1	1410634.JHVD01000035_gene2161	8.3e-13	70.1	COG1115@1|root,COG1115@2|Bacteria,2GIU2@201174|Actinobacteria	201174|Actinobacteria	E	amino acid carrier protein	alaP	-	-	ko:K03310	-	-	-	-	ko00000	2.A.25	-	-	Na_Ala_symp
k141_6248_1	7029.ACYPI56840-PA	2.14e-18	93.6	COG2801@1|root,KOG0017@2759|Eukaryota,38F42@33154|Opisthokonta,3BA5H@33208|Metazoa,3DDWX@33213|Bilateria,42228@6656|Arthropoda,3SPN5@50557|Insecta,3ED9B@33342|Paraneoptera	33208|Metazoa	L	zinc finger	-	-	-	-	-	-	-	-	-	-	-	-	RVP,RVT_1,Retrotrans_gag,rve,zf-CCHC
k141_6248_2	202698.XP_007378181.1	8.41e-13	73.6	COG2801@1|root,KOG0017@2759|Eukaryota,38DPC@33154|Opisthokonta,3NUZ7@4751|Fungi,3UY7N@5204|Basidiomycota,227R3@155619|Agaricomycetes,3H58M@355688|Agaricomycetes incertae sedis	4751|Fungi	L	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	RVT_2,Retrotran_gag_2,gag_pre-integrs,rve
k141_3681_1	1283299.AUKG01000003_gene204	4.23e-15	74.7	COG0372@1|root,COG0372@2|Bacteria,2GJ7E@201174|Actinobacteria,4CPID@84995|Rubrobacteria	84995|Rubrobacteria	C	Belongs to the citrate synthase family	-	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
k141_7978_1	519989.ECTPHS_07331	5.09e-105	331.0	COG0567@1|root,COG0567@2|Bacteria,1MVBF@1224|Proteobacteria,1RN8K@1236|Gammaproteobacteria,1WWM2@135613|Chromatiales	135613|Chromatiales	C	Dehydrogenase E1 component	sucA	-	1.2.4.2	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R00621,R01933,R01940,R03316,R08549	RC00004,RC00027,RC00627,RC02743,RC02833,RC02883	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr
k141_9213_1	1120970.AUBZ01000002_gene907	4.62e-19	82.0	COG5405@1|root,COG5405@2|Bacteria,1MVF2@1224|Proteobacteria,1RP7P@1236|Gammaproteobacteria,4643Y@72275|Alteromonadaceae	1236|Gammaproteobacteria	O	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery	hslV	GO:0000166,GO:0000287,GO:0000502,GO:0003674,GO:0003824,GO:0004175,GO:0004298,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009266,GO:0009376,GO:0009408,GO:0009628,GO:0009987,GO:0016043,GO:0016787,GO:0017076,GO:0019538,GO:0019904,GO:0022607,GO:0030163,GO:0030554,GO:0031597,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034214,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0050896,GO:0051259,GO:0051603,GO:0065003,GO:0070003,GO:0070011,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1904949,GO:1905368,GO:1905369	3.4.25.2	ko:K01419	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Proteasome
k141_9213_2	349124.Hhal_1204	2.09e-58	193.0	COG1220@1|root,COG1220@2|Bacteria,1MVK9@1224|Proteobacteria,1RMYV@1236|Gammaproteobacteria,1WWCI@135613|Chromatiales	135613|Chromatiales	O	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis	hslU	-	-	ko:K03667	-	-	-	-	ko00000,ko03110	-	-	-	AAA_2,ClpB_D2-small
k141_3684_1	671143.DAMO_0297	9.63e-31	124.0	COG5617@1|root,COG5617@2|Bacteria	2|Bacteria	M	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
k141_9215_1	391593.RCCS2_02855	2.57e-76	238.0	COG4177@1|root,COG4177@2|Bacteria,1MUPI@1224|Proteobacteria,2TTN2@28211|Alphaproteobacteria,2P1CB@2433|Roseobacter	28211|Alphaproteobacteria	P	COG4177 ABC-type branched-chain amino acid transport system, permease component	urtC	-	-	ko:K11961	ko02010,map02010	M00323	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4.4,3.A.1.4.5	-	-	BPD_transp_2
k141_9215_2	391593.RCCS2_02860	6.29e-21	88.2	COG4674@1|root,COG4674@2|Bacteria,1MUBR@1224|Proteobacteria,2TQVJ@28211|Alphaproteobacteria,2P1JD@2433|Roseobacter	28211|Alphaproteobacteria	S	transport system, ATPase component	urtD	-	-	ko:K11962	ko02010,map02010	M00323	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4.4,3.A.1.4.5	-	-	ABC_tran,BCA_ABC_TP_C
k141_7982_1	1121104.AQXH01000001_gene1194	2.61e-86	268.0	COG1012@1|root,COG1012@2|Bacteria,4NEB7@976|Bacteroidetes,1INYZ@117747|Sphingobacteriia	976|Bacteroidetes	C	Belongs to the aldehyde dehydrogenase family	aldB	-	1.2.1.3	ko:K00128,ko:K00138	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00711,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
k141_3685_1	1042375.AFPL01000036_gene3004	1.26e-39	140.0	COG3327@1|root,COG3327@2|Bacteria,1R4IF@1224|Proteobacteria,1RR7B@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	phenylacetic acid degradation operon negative regulatory protein	paaX	GO:0000976,GO:0000984,GO:0001017,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0006082,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006805,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009059,GO:0009404,GO:0009407,GO:0009410,GO:0009636,GO:0009850,GO:0009852,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010124,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0010817,GO:0016054,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019439,GO:0019748,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0032774,GO:0032787,GO:0034641,GO:0034645,GO:0034654,GO:0042178,GO:0042221,GO:0042445,GO:0042447,GO:0042537,GO:0043170,GO:0043254,GO:0043436,GO:0043565,GO:0044087,GO:0044212,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044282,GO:0045892,GO:0045934,GO:0046395,GO:0046483,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051716,GO:0060255,GO:0065007,GO:0065008,GO:0070887,GO:0071466,GO:0071704,GO:0072329,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:0098754,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901575,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141	-	ko:K02616	-	-	-	-	ko00000,ko03000	-	-	-	PaaX,PaaX_C
k141_3685_2	1122222.AXWR01000004_gene1690	3.96e-18	84.7	COG1012@1|root,COG2030@1|root,COG1012@2|Bacteria,COG2030@2|Bacteria,1WI85@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	CI	TIGRFAM phenylacetic acid degradation protein paaN	paaZ	-	1.2.1.91,3.3.2.12	ko:K02618	ko00360,ko01120,map00360,map01120	-	R09820,R09836	RC00080,RC02667	ko00000,ko00001,ko01000	-	-	-	Aldedh,MaoC_dehydratas
k141_9216_1	944435.AXAJ01000004_gene2275	6.49e-95	291.0	COG0624@1|root,COG0624@2|Bacteria,1MVUX@1224|Proteobacteria,2W17A@28216|Betaproteobacteria,1KGWW@119060|Burkholderiaceae	28216|Betaproteobacteria	E	the allantoate amidohydrolase from Escherichia coli forms a dimer and binds zinc ions for catalytic activity and catalyzes the conversion of allantoate to (S)-ureidoglycolate and ammonia	-	-	3.5.1.6,3.5.1.87	ko:K06016	ko00240,ko01100,map00240,map01100	M00046	R00905,R04666	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	Peptidase_M20
k141_7983_1	1249997.JHZW01000003_gene2851	1.64e-08	59.7	COG2207@1|root,COG2207@2|Bacteria,4NFVC@976|Bacteroidetes,1HX7J@117743|Flavobacteriia,2PI2I@252356|Maribacter	976|Bacteroidetes	K	Protein of unknown function (DUF4242)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4242,HTH_18
k141_3686_1	765912.Thimo_2520	2.27e-62	205.0	COG4591@1|root,COG4591@2|Bacteria,1R4Q2@1224|Proteobacteria,1RQW0@1236|Gammaproteobacteria,1X1HR@135613|Chromatiales	135613|Chromatiales	M	ABC-type transport system, involved in lipoprotein release, permease component	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
k141_9217_1	1250006.JHZZ01000001_gene225	4.69e-90	269.0	COG0705@1|root,COG0705@2|Bacteria,4NGT3@976|Bacteroidetes,1HXF0@117743|Flavobacteriia,3VW46@52959|Polaribacter	976|Bacteroidetes	S	Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
k141_3687_1	1123070.KB899263_gene1754	9.16e-07	50.4	COG1183@1|root,COG1183@2|Bacteria,46SK0@74201|Verrucomicrobia,2ITHZ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	I	CDP-alcohol phosphatidyltransferase	-	-	2.7.8.8	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	M00093	R01800	RC00002,RC00017,RC02795	ko00000,ko00001,ko00002,ko01000	-	-	-	CDP-OH_P_transf
k141_3687_2	316057.RPD_1841	3.6e-53	179.0	COG0473@1|root,COG0473@2|Bacteria,1MUH4@1224|Proteobacteria,2TSBB@28211|Alphaproteobacteria,3JTGC@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	CE	Isocitrate/isopropylmalate dehydrogenase	MA20_16515	-	1.1.1.83,1.1.1.93,4.1.1.73	ko:K07246	ko00630,ko00650,map00630,map00650	-	R00215,R01751,R02545,R06180	RC00084,RC00105,RC00594	ko00000,ko00001,ko01000	-	-	-	Iso_dh
k141_7986_1	436308.Nmar_1492	3.27e-20	88.6	arCOG03272@1|root,arCOG03272@2157|Archaea	436308.Nmar_1492|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_7986_2	1229909.NSED_08205	1.24e-20	85.1	arCOG10585@1|root,arCOG10585@2157|Archaea,41SW6@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_9222_1	388401.RB2150_01414	5.29e-86	265.0	COG0156@1|root,COG0156@2|Bacteria,1MVVH@1224|Proteobacteria,2TQXI@28211|Alphaproteobacteria,3ZH06@58840|unclassified Rhodobacteraceae	28211|Alphaproteobacteria	H	5-aminolevulinic acid synthase	hemA	-	2.3.1.37	ko:K00643	ko00260,ko00860,ko01100,ko01110,map00260,map00860,map01100,map01110	-	R00830	RC00004,RC02815	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
k141_9223_2	159749.E7BWD8	1.67e-121	359.0	COG0055@1|root,KOG1350@2759|Eukaryota,2XE2T@2836|Bacillariophyta	2836|Bacillariophyta	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpB	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
k141_3691_1	331869.BAL199_15348	1.26e-58	199.0	COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,2TSZ8@28211|Alphaproteobacteria,4BPKK@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	EH	COG0028 Thiamine pyrophosphate-requiring enzymes acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase	alsS	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
k141_3691_2	1207063.P24_12157	9.98e-28	109.0	COG1960@1|root,COG1960@2|Bacteria,1MX17@1224|Proteobacteria,2TTRE@28211|Alphaproteobacteria,2JRJN@204441|Rhodospirillales	204441|Rhodospirillales	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
k141_7992_2	35128.Thaps25022	7.27e-35	133.0	COG1022@1|root,KOG1256@2759|Eukaryota,2XFPU@2836|Bacillariophyta	2836|Bacillariophyta	I	AMP-binding enzyme	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding
k141_9225_1	396595.TK90_1471	2.49e-32	119.0	COG2877@1|root,COG2877@2|Bacteria,1MV91@1224|Proteobacteria,1RMGQ@1236|Gammaproteobacteria,1WWZU@135613|Chromatiales	135613|Chromatiales	M	3-deoxy-D-manno-octulosonic acid 8-phosphate synthase	kdsA	-	2.5.1.55	ko:K01627	ko00540,ko01100,map00540,map01100	M00063	R03254	RC00435	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	DAHP_synth_1
k141_9225_2	1437824.BN940_05711	2.76e-30	117.0	COG0148@1|root,COG0148@2|Bacteria,1MU1N@1224|Proteobacteria,2VH7Y@28216|Betaproteobacteria,3T1EX@506|Alcaligenaceae	28216|Betaproteobacteria	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	GO:0000015,GO:0000287,GO:0003674,GO:0003824,GO:0004634,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005856,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0032991,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043167,GO:0043169,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046872,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902494	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
k141_3693_1	439497.RR11_613	1.81e-28	107.0	COG1846@1|root,COG1846@2|Bacteria,1RIX7@1224|Proteobacteria,2U94M@28211|Alphaproteobacteria,4NAR8@97050|Ruegeria	28211|Alphaproteobacteria	K	helix_turn_helix multiple antibiotic resistance protein	petP	-	-	-	-	-	-	-	-	-	-	-	MarR_2
k141_3693_2	1002340.AFCF01000062_gene672	2.19e-39	137.0	COG0745@1|root,COG0745@2|Bacteria,1MY3D@1224|Proteobacteria,2TSQF@28211|Alphaproteobacteria,34E2B@302485|Phaeobacter	28211|Alphaproteobacteria	K	Transcriptional regulatory protein, C terminal	petR	-	-	ko:K07659	ko02020,ko02026,map02020,map02026	M00445,M00742,M00743	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
k141_7994_1	1121940.AUDZ01000016_gene40	1.9e-98	292.0	COG0410@1|root,COG0410@2|Bacteria,1MUR3@1224|Proteobacteria,1RQZM@1236|Gammaproteobacteria,1XI4N@135619|Oceanospirillales	135619|Oceanospirillales	E	COG0410 ABC-type branched-chain amino acid transport systems, ATPase component	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
k141_7994_2	264198.Reut_B3782	8.25e-06	47.0	COG0411@1|root,COG0411@2|Bacteria,1MX51@1224|Proteobacteria	1224|Proteobacteria	E	amino acid	braF-2	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
k141_9228_1	391593.RCCS2_17206	1.88e-115	350.0	COG0046@1|root,COG0046@2|Bacteria,1MYN4@1224|Proteobacteria,2TRGM@28211|Alphaproteobacteria,2P1U4@2433|Roseobacter	28211|Alphaproteobacteria	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
k141_3696_1	159749.K0S4R8	6.19e-31	130.0	COG0507@1|root,KOG0987@2759|Eukaryota	2759|Eukaryota	L	G-quadruplex DNA unwinding	-	-	-	-	-	-	-	-	-	-	-	-	PIF1
k141_8624_1	35128.Thapsdraft1426	7.59e-22	86.3	28WH7@1|root,2R399@2759|Eukaryota,2XH85@2836|Bacillariophyta	2836|Bacillariophyta	G	Controls the interaction of photosystem II (PSII) cores with the light-harvesting antenna	psbZ	-	-	ko:K02724	ko00195,ko01100,map00195,map01100	-	-	-	ko00000,ko00001,ko00194	-	-	-	Ycf9
k141_8624_5	35128.Thapsdraft93	4.02e-52	181.0	2CACG@1|root,2RWZ1@2759|Eukaryota,2XE6M@2836|Bacillariophyta	2836|Bacillariophyta	S	Uncharacterised protein family	ycf90	-	-	-	-	-	-	-	-	-	-	-	YCF90
k141_9232_1	1286106.MPL1_03298	3.01e-75	243.0	COG1570@1|root,COG1570@2|Bacteria,1MUA4@1224|Proteobacteria,1RNAZ@1236|Gammaproteobacteria,460FW@72273|Thiotrichales	72273|Thiotrichales	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseA	-	3.1.11.6	ko:K03601	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
k141_7996_1	7070.TC001428-PA	4.24e-09	68.2	COG2801@1|root,KOG0017@2759|Eukaryota,38F42@33154|Opisthokonta,3BA5H@33208|Metazoa,3CWAK@33213|Bilateria,41WI3@6656|Arthropoda,3SIRK@50557|Insecta	33208|Metazoa	O	K02A2.6-like	-	-	-	-	-	-	-	-	-	-	-	-	Asp_protease_2,RVT_1,Retrotrans_gag,gag-asp_proteas,rve,zf-CCHC,zf-H2C2
k141_3700_1	1355374.JARU01000001_gene433	2.16e-13	73.2	COG1629@1|root,COG4771@2|Bacteria,1MWKN@1224|Proteobacteria,42MNM@68525|delta/epsilon subdivisions,2YN4N@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	TonB dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
k141_9242_1	1137799.GZ78_14485	0.000792	43.1	COG2801@1|root,COG2801@2|Bacteria,1MVC8@1224|Proteobacteria,1RXYF@1236|Gammaproteobacteria,1XHWD@135619|Oceanospirillales	135619|Oceanospirillales	L	HTH-like domain	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve,rve_3
k141_8002_1	159749.K0RL31	1.5e-42	177.0	COG2801@1|root,KOG0017@2759|Eukaryota,2XF4I@2836|Bacillariophyta	159749.K0RL31|-	L	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_8004_1	1449350.OCH239_20470	2.11e-40	144.0	COG0483@1|root,COG0483@2|Bacteria,1PPJ0@1224|Proteobacteria,2TQTX@28211|Alphaproteobacteria,4KK4R@93682|Roseivivax	28211|Alphaproteobacteria	G	Inositol monophosphatase	hisN	-	3.1.3.15,3.1.3.25,3.1.3.93	ko:K01092,ko:K18649	ko00053,ko00340,ko00521,ko00562,ko01100,ko01110,ko01230,ko04070,map00053,map00340,map00521,map00562,map01100,map01110,map01230,map04070	M00026,M00114,M00131	R01185,R01186,R01187,R03013,R07674	RC00017,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
k141_5027_1	985054.JQEZ01000001_gene2872	1.74e-70	226.0	COG3039@1|root,COG3039@2|Bacteria,1MUVI@1224|Proteobacteria,2TSA7@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_6,DUF772
k141_5640_1	1410676.JNKL01000035_gene1089	5.38e-15	70.1	COG0268@1|root,COG0268@2|Bacteria,1MZ94@1224|Proteobacteria,1S9AI@1236|Gammaproteobacteria,1Y4NK@135624|Aeromonadales	135624|Aeromonadales	J	Binds directly to 16S ribosomal RNA	rpsT	-	-	ko:K02968	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S20p
k141_5640_2	187272.Mlg_0848	1.14e-42	150.0	COG0263@1|root,COG0263@2|Bacteria,1MUBG@1224|Proteobacteria,1RM7X@1236|Gammaproteobacteria,1WWMC@135613|Chromatiales	135613|Chromatiales	E	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate	proB	-	2.7.2.11	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	M00015	R00239	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,PUA
k141_5028_1	983545.Glaag_0689	1.13e-07	58.2	COG0845@1|root,COG0845@2|Bacteria,1MVFN@1224|Proteobacteria,1RNN6@1236|Gammaproteobacteria,466K4@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	Biotin-lipoyl like	-	-	-	ko:K18990	-	M00720	-	-	ko00000,ko00002,ko02000	2.A.6.2.30,8.A.1	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
k141_1333_1	1229909.NSED_01325	1.32e-150	441.0	COG1009@1|root,arCOG01539@2157|Archaea,41SC4@651137|Thaumarchaeota	651137|Thaumarchaeota	C	TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain L	-	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M,Proton_antipo_N
k141_8090_1	426114.THI_0212	2.34e-32	129.0	COG3459@1|root,COG3459@2|Bacteria,1MVNX@1224|Proteobacteria,2VKDG@28216|Betaproteobacteria	28216|Betaproteobacteria	G	carbohydrate binding	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_36,Glyco_transf_36,Glycoamylase
k141_1950_1	1469613.JT55_00105	4.75e-80	254.0	COG0111@1|root,COG0111@2|Bacteria,1MU5Z@1224|Proteobacteria,2TR0F@28211|Alphaproteobacteria,3FCGV@34008|Rhodovulum	28211|Alphaproteobacteria	EH	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain	serA	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C,ACT
k141_5641_1	631362.Thi970DRAFT_00974	5.08e-37	135.0	COG0809@1|root,COG0809@2|Bacteria,1MUH3@1224|Proteobacteria,1RMKW@1236|Gammaproteobacteria,1WW5P@135613|Chromatiales	135613|Chromatiales	J	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	queA	-	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
k141_5641_2	1123054.KB907715_gene51	1.62e-34	128.0	COG0343@1|root,COG0343@2|Bacteria,1MUCA@1224|Proteobacteria,1RMY3@1236|Gammaproteobacteria,1WWQ8@135613|Chromatiales	135613|Chromatiales	J	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	tgt	-	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
k141_3174_1	331869.BAL199_16283	8.6e-47	160.0	COG4123@1|root,COG4123@2|Bacteria,1MXEQ@1224|Proteobacteria,2TUBR@28211|Alphaproteobacteria,4BQP0@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	S	Methyltransferase small domain	yfiC	-	2.1.1.223	ko:K15460	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	MTS
k141_3789_2	35128.Thapsdraft997	2.99e-10	60.5	COG0086@1|root,2RUNJ@2759|Eukaryota,2XENN@2836|Bacillariophyta	2836|Bacillariophyta	H	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	-	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009536,GO:0030880,GO:0032991,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0061695,GO:1902494,GO:1990234	-	-	-	-	-	-	-	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3
k141_92_2	159749.E7BWJ3	2.6e-227	643.0	28JJ8@1|root,2QRYE@2759|Eukaryota	2759|Eukaryota	C	chlorophyll binding	psaA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009534,GO:0009535,GO:0009536,GO:0009579,GO:0016020,GO:0031976,GO:0031984,GO:0034357,GO:0042651,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044436,GO:0044444,GO:0044446,GO:0044464,GO:0055035	-	ko:K02689,ko:K02690	ko00195,ko01100,map00195,map01100	M00163	-	-	ko00000,ko00001,ko00002,ko00194	-	-	-	PsaA_PsaB
k141_5029_1	1469245.JFBG01000056_gene2467	2.89e-86	274.0	28JZQ@1|root,2Z9PN@2|Bacteria,1N2WN@1224|Proteobacteria,1S4QJ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_715_1	5037.XP_001535788.1	1.79e-14	77.8	COG2801@1|root,KOG0017@2759|Eukaryota,38DPC@33154|Opisthokonta,3NUZ7@4751|Fungi,3QNZW@4890|Ascomycota,20FR9@147545|Eurotiomycetes,3B52A@33183|Onygenales	4751|Fungi	L	to reverse transcriptase	-	-	2.1.1.310	ko:K14835	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	DDE_1,RVT_2,gag_pre-integrs,rve
k141_6875_1	400682.PAC_15699223	3.27e-59	197.0	COG2801@1|root,KOG0017@2759|Eukaryota,38F42@33154|Opisthokonta,3BA5H@33208|Metazoa	33208|Metazoa	OU	K02A2.6-like	-	-	-	-	-	-	-	-	-	-	-	-	RVT_1
k141_8091_1	95619.PM1_0216640	1.03e-98	305.0	COG0608@1|root,COG0608@2|Bacteria,1MU1M@1224|Proteobacteria,1RMF4@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Single-stranded-DNA-specific exonuclease	recJ	GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008297,GO:0008409,GO:0009314,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0033554,GO:0034641,GO:0035312,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0045145,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
k141_1335_1	1411685.U062_02290	3.97e-72	227.0	COG0429@1|root,COG0429@2|Bacteria,1MWV1@1224|Proteobacteria,1RN39@1236|Gammaproteobacteria,1J5UY@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	hydrolase of the alpha beta-hydrolase fold	-	-	-	ko:K07019	-	-	-	-	ko00000	-	-	-	Abhydrolase_1,Abhydrolase_6,Hydrolase_4
k141_6266_2	314271.RB2654_07114	1.76e-92	278.0	COG0329@1|root,COG0329@2|Bacteria,1Q3N4@1224|Proteobacteria,2U64R@28211|Alphaproteobacteria	28211|Alphaproteobacteria	EM	Belongs to the DapA family	-	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
k141_7468_1	349163.Acry_0366	2.34e-162	474.0	COG0465@1|root,COG0465@2|Bacteria,1MU6J@1224|Proteobacteria,2TSYQ@28211|Alphaproteobacteria,2JV0M@204441|Rhodospirillales	204441|Rhodospirillales	O	FtsH Extracellular	-	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
k141_5031_1	314278.NB231_05601	1.42e-70	226.0	COG0772@1|root,COG0772@2|Bacteria,1MVDB@1224|Proteobacteria,1RMIV@1236|Gammaproteobacteria,1WWCK@135613|Chromatiales	135613|Chromatiales	M	Peptidoglycan polymerase that is essential for cell division	ftsW	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
k141_717_1	1027273.GZ77_17190	2.4e-07	57.4	COG2982@1|root,COG2982@2|Bacteria,1NVUY@1224|Proteobacteria,1RPFM@1236|Gammaproteobacteria,1XI8B@135619|Oceanospirillales	135619|Oceanospirillales	M	protein involved in outer membrane biogenesis	-	-	-	ko:K07289	-	-	-	-	ko00000	-	-	-	AsmA
k141_6877_1	1121935.AQXX01000140_gene1030	1.91e-17	81.3	COG4166@1|root,COG4166@2|Bacteria,1P91R@1224|Proteobacteria,1RN57@1236|Gammaproteobacteria,1XHY0@135619|Oceanospirillales	135619|Oceanospirillales	E	Peptide ABC transporter substrate-binding protein	-	-	-	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	SBP_bac_5
k141_6877_2	1121935.AQXX01000140_gene1031	8.04e-47	159.0	COG0601@1|root,COG0601@2|Bacteria,1MU8Z@1224|Proteobacteria,1RNJ1@1236|Gammaproteobacteria,1XJ29@135619|Oceanospirillales	135619|Oceanospirillales	P	transporter, permease	-	-	-	ko:K02033,ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1
k141_8707_1	7070.TC001491-PA	1.78e-07	59.3	COG2801@1|root,KOG0017@2759|Eukaryota,38F42@33154|Opisthokonta,3BA5H@33208|Metazoa,3CWAK@33213|Bilateria,41WI3@6656|Arthropoda,3SIRK@50557|Insecta	33208|Metazoa	O	K02A2.6-like	-	-	-	-	-	-	-	-	-	-	-	-	Baculo_F,RVT_1,rve
k141_5948_1	1122135.KB893137_gene1235	2.8e-34	126.0	COG4177@1|root,COG4177@2|Bacteria,1MV66@1224|Proteobacteria,2TT64@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Belongs to the binding-protein-dependent transport system permease family	MA20_22605	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
k141_5948_2	1380347.JNII01000006_gene1129	2.71e-15	75.5	COG0410@1|root,COG0410@2|Bacteria,2GKSQ@201174|Actinobacteria,4ESPS@85013|Frankiales	201174|Actinobacteria	E	High-affinity branched-chain amino acid transport protein (ABC superfamily	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
k141_404_1	1280001.BAOA01000033_gene2228	6.35e-24	92.0	2E4EA@1|root,32Z9I@2|Bacteria,1N7HE@1224|Proteobacteria,1SDU5@1236|Gammaproteobacteria,1XYY5@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_9632_1	1238182.C882_0535	5.57e-94	283.0	COG0191@1|root,COG0191@2|Bacteria,1MURX@1224|Proteobacteria,2TSAD@28211|Alphaproteobacteria,2JQ1D@204441|Rhodospirillales	204441|Rhodospirillales	G	Fructose-bisphosphate aldolase class-II	cbbA	-	4.1.2.13	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167,M00344,M00345	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	F_bP_aldolase
k141_7183_1	1123376.AUIU01000002_gene1663	1.74e-91	290.0	COG0466@1|root,COG0466@2|Bacteria,3J0DQ@40117|Nitrospirae	40117|Nitrospirae	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	-	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
k141_6569_1	159749.K0SEJ4	1.44e-36	142.0	COG2801@1|root,KOG0017@2759|Eukaryota,2XHU4@2836|Bacillariophyta	159749.K0SEJ4|-	L	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_7750_1	1127673.GLIP_0274	2.88e-36	129.0	COG4535@1|root,COG4535@2|Bacteria,1QTU8@1224|Proteobacteria,1RMKX@1236|Gammaproteobacteria,4658M@72275|Alteromonadaceae	1236|Gammaproteobacteria	P	Mg2 and Co2 transporter CorC	corC	GO:0001897,GO:0001906,GO:0001907,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0009405,GO:0009987,GO:0016020,GO:0019835,GO:0019836,GO:0031640,GO:0035821,GO:0044003,GO:0044004,GO:0044179,GO:0044364,GO:0044403,GO:0044419,GO:0044464,GO:0044764,GO:0051701,GO:0051704,GO:0051715,GO:0051801,GO:0051817,GO:0051818,GO:0051883,GO:0052331,GO:0071944	-	ko:K06189	-	-	-	-	ko00000,ko02000	9.A.40.1.2	-	-	CBS,CorC_HlyC
k141_7750_2	493475.GARC_0241	2e-29	117.0	COG0815@1|root,COG0815@2|Bacteria,1MUBU@1224|Proteobacteria,1RM8M@1236|Gammaproteobacteria,46473@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	Transfers the fatty acyl group on membrane lipoproteins	lnt	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016021,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0031224,GO:0031226,GO:0034645,GO:0036211,GO:0042157,GO:0042158,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576	-	ko:K03820	-	-	-	-	ko00000,ko01000	-	GT2	iEcSMS35_1347.EcSMS35_0678,iSbBS512_1146.SbBS512_E0590	CN_hydrolase
k141_8384_1	395494.Galf_2270	2.49e-51	171.0	COG0142@1|root,COG0142@2|Bacteria,1MWNG@1224|Proteobacteria,2VHQV@28216|Betaproteobacteria,44V0J@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Polyprenyl synthetase	ispA	-	2.5.1.1,2.5.1.10	ko:K00795	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364	R01658,R02003	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
k141_8384_2	1131553.JIBI01000065_gene1016	2.57e-09	54.3	COG1722@1|root,COG1722@2|Bacteria,1PTYP@1224|Proteobacteria,2VVQV@28216|Betaproteobacteria,373KV@32003|Nitrosomonadales	28216|Betaproteobacteria	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseB	-	3.1.11.6	ko:K03602	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_S
k141_3459_1	870187.Thini_3708	1.82e-116	350.0	COG0459@1|root,COG0459@2|Bacteria,1MURR@1224|Proteobacteria,1RMTB@1236|Gammaproteobacteria,4600M@72273|Thiotrichales	72273|Thiotrichales	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	-	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
k141_4728_1	1207063.P24_17533	5.04e-60	197.0	COG0014@1|root,COG0014@2|Bacteria,1MUGJ@1224|Proteobacteria,2TS83@28211|Alphaproteobacteria,2JQNS@204441|Rhodospirillales	204441|Rhodospirillales	E	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate	proA	-	1.2.1.41	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	M00015	R03313	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
k141_4108_1	349521.HCH_05197	2.99e-42	154.0	COG5000@1|root,COG5000@2|Bacteria,1QUG9@1224|Proteobacteria,1T1Y1@1236|Gammaproteobacteria,1XRTE@135619|Oceanospirillales	135619|Oceanospirillales	T	His Kinase A (phosphoacceptor) domain	-	-	2.7.13.3	ko:K10942	ko02020,ko05111,map02020,map05111	M00515	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,PAS_8
k141_405_1	1207063.P24_16040	5.17e-98	303.0	COG3333@1|root,COG3333@2|Bacteria,1MUKR@1224|Proteobacteria,2TR4Q@28211|Alphaproteobacteria,2JQDH@204441|Rhodospirillales	204441|Rhodospirillales	S	Tripartite tricarboxylate transporter TctA family	-	-	-	ko:K07793	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.80.1	-	-	TctA
k141_2261_1	999550.KI421507_gene3246	9.26e-55	188.0	COG2303@1|root,COG2303@2|Bacteria,1MV19@1224|Proteobacteria,2TQKQ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate	alkJ2	-	1.1.99.1	ko:K00108	ko00260,ko01100,map00260,map01100	M00555	R01025	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	GMC_oxred_C,GMC_oxred_N
k141_9634_1	398720.MED217_04592	1.09e-64	210.0	COG4225@1|root,COG4225@2|Bacteria,4NFWI@976|Bacteroidetes,1HZCS@117743|Flavobacteriia,2XJR9@283735|Leeuwenhoekiella	976|Bacteroidetes	S	unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins	-	-	3.2.1.172	ko:K15532	-	-	-	-	ko00000,ko01000	-	GH105	-	Glyco_hydro_88
k141_6571_1	1144275.COCOR_01695	8.72e-33	127.0	COG3268@1|root,COG3268@2|Bacteria,1MVI3@1224|Proteobacteria,431ET@68525|delta/epsilon subdivisions,2WWV2@28221|Deltaproteobacteria,2YX5R@29|Myxococcales	28221|Deltaproteobacteria	S	Saccharopine dehydrogenase NADP binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Sacchrp_dh_NADP
k141_4109_1	1278309.KB907099_gene2798	3.98e-109	328.0	COG1760@1|root,COG1760@2|Bacteria,1MUZN@1224|Proteobacteria,1RMJZ@1236|Gammaproteobacteria,1XIF9@135619|Oceanospirillales	135619|Oceanospirillales	E	Serine dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	SDH_alpha,SDH_beta
k141_5950_1	502025.Hoch_2359	3.13e-60	209.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2WJ8D@28221|Deltaproteobacteria,2YXGU@29|Myxococcales	28221|Deltaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
k141_7753_1	751994.AGIG01000030_gene780	2.25e-11	63.2	COG0842@1|root,COG0842@2|Bacteria,1MUH1@1224|Proteobacteria,1RP0Z@1236|Gammaproteobacteria,1J4RI@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	V	COG0842 ABC-type multidrug transport system, permease component	yadH	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
k141_7753_2	493475.GARC_2149	1.25e-37	137.0	COG1131@1|root,COG1131@2|Bacteria,1MUW7@1224|Proteobacteria,1RMC5@1236|Gammaproteobacteria,465BH@72275|Alteromonadaceae	1236|Gammaproteobacteria	V	COG1131 ABC-type multidrug transport system, ATPase component	yadG	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0009314,GO:0009628,GO:0010165,GO:0010212,GO:0016020,GO:0044464,GO:0050896,GO:0071944	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
k141_4730_1	425104.Ssed_1377	2.52e-27	112.0	COG0657@1|root,COG0657@2|Bacteria,1RD8A@1224|Proteobacteria,1S3TH@1236|Gammaproteobacteria,2QAZF@267890|Shewanellaceae	1236|Gammaproteobacteria	I	PFAM Alpha beta hydrolase fold-3 domain protein	aes	-	3.1.1.83	ko:K14731	ko00903,ko00930,ko01220,map00903,map00930,map01220	-	R03751,R06390,R06391,R06392,R06393	RC00713,RC00983,RC01505	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_3
k141_5951_1	159749.K0TQC7	1.96e-29	121.0	COG2801@1|root,KOG0017@2759|Eukaryota,2XF4I@2836|Bacillariophyta	159749.K0TQC7|-	L	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_1644_1	375451.RD1_4061	3.21e-104	324.0	COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,2TS19@28211|Alphaproteobacteria,2P1XW@2433|Roseobacter	28211|Alphaproteobacteria	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	nrdZ	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_lgC,Ribonuc_red_lgN
k141_8388_1	1229909.NSED_00220	2.46e-83	251.0	COG0090@1|root,arCOG04067@2157|Archaea,41SCT@651137|Thaumarchaeota	651137|Thaumarchaeota	J	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity	rpl2	-	-	ko:K02886	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L2,Ribosomal_L2_C
k141_3462_1	404380.Gbem_1577	2e-40	151.0	COG1201@1|root,COG1201@2|Bacteria,1MUSW@1224|Proteobacteria,42Q75@68525|delta/epsilon subdivisions,2WMDY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	DEAD DEAH box	-	-	-	ko:K03724	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DEAD_assoc,Helicase_C
k141_2263_1	159749.E7BWJ2	6.64e-156	457.0	28JJ8@1|root,2QRYE@2759|Eukaryota,2XEB4@2836|Bacillariophyta	2836|Bacillariophyta	C	PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX. PSI is a plastocyanin cytochrome c6-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn. Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin or cytochrome c6	psaB	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009534,GO:0009535,GO:0009536,GO:0009579,GO:0016020,GO:0016168,GO:0031976,GO:0031984,GO:0034357,GO:0042651,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044436,GO:0044444,GO:0044446,GO:0044464,GO:0046906,GO:0048037,GO:0055035,GO:0097159,GO:1901363	-	ko:K02690	ko00195,ko01100,map00195,map01100	M00163	-	-	ko00000,ko00001,ko00002,ko00194	-	-	-	PsaA_PsaB
k141_1021_1	439235.Dalk_2704	1.75e-94	283.0	292MF@1|root,2ZQ5C@2|Bacteria,1RCYR@1224|Proteobacteria,42RFG@68525|delta/epsilon subdivisions,2WPKN@28221|Deltaproteobacteria,2MK0P@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF3047)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3047
k141_4112_1	595460.RRSWK_01365	3.87e-70	227.0	COG5361@1|root,COG5361@2|Bacteria,2IYY0@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF1214)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1214,DUF1254
k141_2879_1	671143.DAMO_1445	2.44e-61	212.0	COG0417@1|root,COG1205@1|root,COG0417@2|Bacteria,COG1205@2|Bacteria,2NNKJ@2323|unclassified Bacteria	2|Bacteria	L	Domain of unknown function (DUF1998)	yprA	GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360	2.7.7.7	ko:K02336,ko:K06877	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DNA_pol_B,DNA_pol_B_exo1,DUF1998,Helicase_C
k141_3463_1	1403313.AXBR01000008_gene612	1.43e-05	50.8	COG0443@1|root,COG0443@2|Bacteria,1TP1J@1239|Firmicutes,4HA9S@91061|Bacilli,1ZAZ2@1386|Bacillus	91061|Bacilli	O	Heat shock 70 kDa protein	dnaK	GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0008150,GO:0009986,GO:0030246,GO:0030247,GO:0044464,GO:0051704,GO:0098630,GO:0098743,GO:2001065	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
k141_409_1	1036674.A28LD_1031	2.62e-06	54.7	COG3428@1|root,COG3428@2|Bacteria,1R51P@1224|Proteobacteria,1RNVC@1236|Gammaproteobacteria,2QG68@267893|Idiomarinaceae	1236|Gammaproteobacteria	S	Bacterial PH domain	-	-	-	ko:K08981	-	-	-	-	ko00000	-	-	-	bPH_2
k141_5953_1	382464.ABSI01000012_gene2200	3.73e-56	196.0	COG0457@1|root,COG5616@1|root,COG0457@2|Bacteria,COG5616@2|Bacteria	2|Bacteria	S	cAMP biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,TPR_11,TPR_16,TPR_7,TPR_8,Trans_reg_C
k141_7189_1	1307437.J139_12118	3.5e-52	179.0	COG1207@1|root,COG1207@2|Bacteria,1MUPH@1224|Proteobacteria,1RNKE@1236|Gammaproteobacteria,2Q077@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	M	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain	glmU	GO:0000270,GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0003977,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006022,GO:0006023,GO:0006024,GO:0006040,GO:0006047,GO:0006048,GO:0006139,GO:0006629,GO:0006725,GO:0006793,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009225,GO:0009226,GO:0009252,GO:0009273,GO:0009987,GO:0016051,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0016772,GO:0016779,GO:0018130,GO:0019134,GO:0019438,GO:0030203,GO:0033692,GO:0034637,GO:0034641,GO:0034645,GO:0034654,GO:0042546,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046349,GO:0046483,GO:0046872,GO:0055086,GO:0070569,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1903509	2.3.1.157,2.7.7.23	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00362	R00416,R05332	RC00002,RC00004,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	iECED1_1282.ECED1_4420,iYL1228.KPN_04135	Hexapep,Hexapep_2,NTP_transf_3
k141_1646_1	1384054.N790_02135	7.22e-05	50.4	COG0457@1|root,COG0457@2|Bacteria,1MVMG@1224|Proteobacteria,1RWPV@1236|Gammaproteobacteria,1X68T@135614|Xanthomonadales	135614|Xanthomonadales	S	Sulfotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_3
k141_3464_1	1120983.KB894572_gene3112	9.17e-76	251.0	COG0365@1|root,COG0654@1|root,COG0365@2|Bacteria,COG0654@2|Bacteria,1MUF5@1224|Proteobacteria,2TR3P@28211|Alphaproteobacteria,1JNCA@119043|Rhodobiaceae	28211|Alphaproteobacteria	I	AMP-binding enzyme C-terminal domain	-	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C,FAD_binding_3
k141_410_1	1229909.NSED_00960	1.31e-42	139.0	COG2075@1|root,arCOG01950@2157|Archaea,41T7M@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Binds to the 23S rRNA	rpl24e	-	-	ko:K02896	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L24e
k141_410_2	1229909.NSED_00955	2.9e-34	118.0	COG2053@1|root,arCOG04314@2157|Archaea,41ST6@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Belongs to the eukaryotic ribosomal protein eS28 family	rps28e	-	-	ko:K02979	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S28e
k141_410_3	1229909.NSED_00950	1.15e-45	149.0	COG1358@1|root,arCOG01751@2157|Archaea,41SMS@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Multifunctional RNA-binding protein that recognizes the K-turn motif in ribosomal RNA, the RNA component of RNase P, box H ACA, box C D and box C' D' sRNAs	rpl7ae	-	-	ko:K02936	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03009,ko03011	-	-	-	Ribosomal_L7Ae
k141_4113_2	35128.Thapsdraft1243	1.03e-36	124.0	COG0267@1|root,2S7HT@2759|Eukaryota,2XH5S@2836|Bacillariophyta	2836|Bacillariophyta	J	Ribosomal protein L33	rpl33	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009536,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464	-	-	-	-	-	-	-	-	-	-	Ribosomal_L33
k141_4113_3	35128.Thapsdraft1251	3.35e-32	113.0	KOG3162@1|root,KOG3162@2759|Eukaryota,2XH9V@2836|Bacillariophyta	2836|Bacillariophyta	J	Ribosomal protein S18	-	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009507,GO:0009536,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	-	-	-	-	-	-	-	-	-	Ribosomal_S18
k141_7758_1	1089550.ATTH01000001_gene123	2.44e-18	88.2	COG4867@1|root,COG4867@2|Bacteria,4NFMA@976|Bacteroidetes,1FIKS@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	von Willebrand factor (vWF) type A domain	-	-	-	-	-	-	-	-	-	-	-	-	VWA_2
k141_4734_1	1121479.AUBS01000014_gene1155	3.15e-75	245.0	COG0145@1|root,COG0145@2|Bacteria,1MU2Y@1224|Proteobacteria,2TQZ6@28211|Alphaproteobacteria	28211|Alphaproteobacteria	EQ	N-methylhydantoinase A acetone carboxylase, beta subunit	-	-	3.5.2.14	ko:K01473	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydant_A_N,Hydantoinase_A
k141_9702_1	1121878.AUGL01000021_gene2815	1.08e-81	260.0	28HMZ@1|root,2Z7WD@2|Bacteria,1MU3Q@1224|Proteobacteria,1RRUM@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF3604)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3604
k141_7817_1	83219.PM02_09605	1.43e-100	297.0	COG4176@1|root,COG4176@2|Bacteria,1QTTE@1224|Proteobacteria,2TS3U@28211|Alphaproteobacteria,3ZWYZ@60136|Sulfitobacter	28211|Alphaproteobacteria	E	Binding-protein-dependent transport system inner membrane component	choW	-	-	ko:K02001	ko02010,map02010	M00208	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	BPD_transp_1
k141_4800_1	1392490.JHZX01000001_gene2168	3.86e-15	74.7	COG3934@1|root,COG3934@2|Bacteria,4NHVX@976|Bacteroidetes,1HY3I@117743|Flavobacteriia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	-	-	-	-	-	-	-	-	-	-	-	-	Cellulase,Glyco_hydro_2_C
k141_4800_2	313594.PI23P_11502	7.56e-36	134.0	COG3934@1|root,COG3934@2|Bacteria,4NHVX@976|Bacteroidetes,1HY3I@117743|Flavobacteriia,3VUZD@52959|Polaribacter	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	-	-	-	-	-	-	-	-	-	-	-	-	Cellulase,Glyco_hydro_2_C
k141_9048_1	1121937.AUHJ01000026_gene24	1.96e-68	217.0	COG3547@1|root,COG3547@2|Bacteria,1MUER@1224|Proteobacteria,1RMAQ@1236|Gammaproteobacteria,465EU@72275|Alteromonadaceae	1236|Gammaproteobacteria	L	COG3547 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k141_1090_1	1158165.KB898872_gene761	5.48e-20	94.0	COG1520@1|root,COG1520@2|Bacteria,1MXIJ@1224|Proteobacteria,1RN4V@1236|Gammaproteobacteria,1WWQT@135613|Chromatiales	135613|Chromatiales	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamB	-	-	ko:K17713	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	PQQ_2,PQQ_3
k141_1714_1	1270193.JARP01000002_gene643	1.84e-12	61.6	COG0236@1|root,COG0236@2|Bacteria,4NS6C@976|Bacteroidetes,1I3VI@117743|Flavobacteriia,2NX59@237|Flavobacterium	976|Bacteroidetes	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
k141_1714_2	1178825.ALIH01000003_gene2168	3.84e-43	145.0	COG0299@1|root,COG0299@2|Bacteria,4NNZP@976|Bacteroidetes,1I19R@117743|Flavobacteriia	976|Bacteroidetes	F	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate	purN	-	2.1.2.2	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	Formyl_trans_N
k141_8460_1	1485545.JQLW01000006_gene297	2.14e-48	176.0	COG0515@1|root,COG4252@1|root,COG0515@2|Bacteria,COG4252@2|Bacteria,1MV1P@1224|Proteobacteria	1224|Proteobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	CHASE2,Pkinase
k141_478_1	159749.E7BWI1	7.03e-116	344.0	COG1850@1|root,2QTI9@2759|Eukaryota,2XE5R@2836|Bacillariophyta	2836|Bacillariophyta	Q	RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process. Both reactions occur simultaneously and in competition at the same active site	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009536,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464	4.1.1.39	ko:K01601	ko00630,ko00710,ko01100,ko01120,ko01200,map00630,map00710,map01100,map01120,map01200	M00165,M00166,M00532	R00024,R03140	RC00172,RC00859	ko00000,ko00001,ko00002,ko01000	-	-	-	RuBisCO_large,RuBisCO_large_N
k141_1091_1	357804.Ping_0439	9.46e-15	73.6	COG0726@1|root,COG0726@2|Bacteria,1P78Y@1224|Proteobacteria,1TDBB@1236|Gammaproteobacteria,2QHKN@267894|Psychromonadaceae	1236|Gammaproteobacteria	G	polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_1715_1	1122614.JHZF01000016_gene498	6.05e-107	318.0	COG0665@1|root,COG0665@2|Bacteria,1MVM6@1224|Proteobacteria,2TRM7@28211|Alphaproteobacteria,2PDPC@252301|Oceanicola	28211|Alphaproteobacteria	E	COG0665 Glycine D-amino acid oxidases (deaminating)	soxB3	-	1.5.3.1	ko:K00303	ko00260,ko01100,map00260,map01100	-	R00610	RC00060,RC00557	ko00000,ko00001,ko01000	-	-	-	DAO
k141_7819_1	1049564.TevJSym_ag00880	2.44e-139	411.0	COG1053@1|root,COG1053@2|Bacteria,1NZBR@1224|Proteobacteria,1RZ0U@1236|Gammaproteobacteria,1JAJ9@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Fumarate reductase flavoprotein C-term	aprA	-	1.8.99.2	ko:K00394	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00596	R00860,R04927,R08553	RC00007,RC01239,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
k141_6646_1	1449126.JQKL01000010_gene417	5.38e-10	59.7	COG1354@1|root,COG1354@2|Bacteria,1TRW3@1239|Firmicutes,249VW@186801|Clostridia,269NT@186813|unclassified Clostridiales	186801|Clostridia	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves	scpA	-	-	ko:K05896	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpA
k141_6646_2	330214.NIDE3366	1.56e-51	175.0	COG0180@1|root,COG0180@2|Bacteria,3J0A0@40117|Nitrospirae	40117|Nitrospirae	J	tRNA synthetases class I (W and Y)	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
k141_9706_1	1123400.KB904813_gene2991	1.3e-62	202.0	COG0583@1|root,COG0583@2|Bacteria,1MWY0@1224|Proteobacteria,1RP7Q@1236|Gammaproteobacteria,461BK@72273|Thiotrichales	72273|Thiotrichales	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
k141_6018_1	1150626.PHAMO_30062	3.49e-138	411.0	COG1185@1|root,COG1185@2|Bacteria,1MVB9@1224|Proteobacteria,2TRH3@28211|Alphaproteobacteria,2JPZ2@204441|Rhodospirillales	204441|Rhodospirillales	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	-	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
k141_760_2	1123399.AQVE01000025_gene1967	4.97e-53	171.0	COG0290@1|root,COG0290@2|Bacteria,1RDD2@1224|Proteobacteria,1S4E6@1236|Gammaproteobacteria,460MP@72273|Thiotrichales	72273|Thiotrichales	J	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins	infC	-	-	ko:K02520	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	IF3_C,IF3_N
k141_7501_1	467661.RKLH11_3631	4.29e-131	379.0	COG2801@1|root,COG2963@1|root,COG2801@2|Bacteria,COG2963@2|Bacteria,1PBHA@1224|Proteobacteria,2TRQF@28211|Alphaproteobacteria,3ZI18@58840|unclassified Rhodobacteraceae	28211|Alphaproteobacteria	L	L COG2801 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	HTH_32,rve,rve_3
k141_5078_1	89187.ISM_04945	3.82e-125	371.0	COG0843@1|root,COG0843@2|Bacteria,1MU7S@1224|Proteobacteria,2TQP1@28211|Alphaproteobacteria,46PUE@74030|Roseovarius	28211|Alphaproteobacteria	C	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B	ctaD	GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015672,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0022900,GO:0022904,GO:0034220,GO:0044237,GO:0044464,GO:0045333,GO:0051179,GO:0051234,GO:0055085,GO:0055114,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:1902600	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
k141_8134_1	1342299.Z947_953	1.46e-37	137.0	COG1541@1|root,COG1541@2|Bacteria,1MV1W@1224|Proteobacteria,2TRVF@28211|Alphaproteobacteria,3ZVEC@60136|Sulfitobacter	28211|Alphaproteobacteria	H	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)	paaF	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C_2
k141_8134_2	1090320.KB900605_gene3045	9.69e-14	70.5	COG1012@1|root,COG2030@1|root,COG1012@2|Bacteria,COG2030@2|Bacteria,1MWD4@1224|Proteobacteria,2TUPI@28211|Alphaproteobacteria,2K1V8@204457|Sphingomonadales	204457|Sphingomonadales	CI	MaoC like domain	-	-	1.2.1.91,3.3.2.12	ko:K02618	ko00360,ko01120,map00360,map01120	-	R09820,R09836	RC00080,RC02667	ko00000,ko00001,ko01000	-	-	-	Aldedh,MaoC_dehydratas
k141_1378_1	243090.RB3320	1.14e-54	186.0	COG5361@1|root,COG5361@2|Bacteria,2IYY0@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF1214)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1214,DUF1254
k141_4466_2	159749.E7BWD2	0.0	900.0	COG0086@1|root,2RUNJ@2759|Eukaryota,2XENN@2836|Bacillariophyta	2836|Bacillariophyta	H	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	-	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009536,GO:0030880,GO:0032991,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0061695,GO:1902494,GO:1990234	-	-	-	-	-	-	-	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3
k141_5690_1	290398.Csal_3286	1.93e-89	277.0	COG0056@1|root,COG0056@2|Bacteria,1MUG7@1224|Proteobacteria,1RP4V@1236|Gammaproteobacteria,1XHRG@135619|Oceanospirillales	135619|Oceanospirillales	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
k141_5079_1	1123368.AUIS01000003_gene1740	1.98e-53	184.0	COG0793@1|root,COG0793@2|Bacteria,1MU39@1224|Proteobacteria,1RMSR@1236|Gammaproteobacteria,2NC02@225057|Acidithiobacillales	225057|Acidithiobacillales	M	Belongs to the peptidase S41A family	-	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_S41
k141_6316_1	2850.Phatr49367	3.95e-27	114.0	2EHC8@1|root,2SN1N@2759|Eukaryota,2XFZ0@2836|Bacillariophyta	2836|Bacillariophyta	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_762_1	861299.J421_0610	0.000229	45.8	COG0515@1|root,COG0515@2|Bacteria,1ZUF3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
k141_762_2	1211115.ALIQ01000198_gene438	1.43e-29	112.0	COG2084@1|root,COG2084@2|Bacteria,1MWR4@1224|Proteobacteria,2U157@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	3-hydroxyisobutyrate dehydrogenase	MA20_14105	-	1.1.1.31	ko:K00020	ko00280,ko01100,map00280,map01100	-	R05066	RC00099	ko00000,ko00001,ko01000	-	-	-	NAD_binding_11,NAD_binding_2
k141_3222_1	160488.PP_4872	5.89e-96	301.0	COG1032@1|root,COG1032@2|Bacteria,1MUG3@1224|Proteobacteria,1RN9V@1236|Gammaproteobacteria,1YWNZ@136845|Pseudomonas putida group	1236|Gammaproteobacteria	C	UPF0313 protein	ygiQ	-	-	-	-	-	-	-	-	-	-	-	DUF3362,Radical_SAM,Radical_SAM_N
k141_4467_2	1123501.KB902313_gene2933	4.09e-66	207.0	COG2993@1|root,COG2993@2|Bacteria,1MXEY@1224|Proteobacteria,2TRGW@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	COG2993 Cbb3-type cytochrome oxidase, cytochrome c subunit	ccoO	-	-	ko:K00405	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	FixO
k141_2002_1	398580.Dshi_3398	2.9e-74	225.0	COG3335@1|root,COG3335@2|Bacteria,1P76X@1224|Proteobacteria,2U16U@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3
k141_3838_1	935261.JAGL01000019_gene594	2.03e-52	179.0	COG0404@1|root,COG0404@2|Bacteria,1R3WG@1224|Proteobacteria,2U0M4@28211|Alphaproteobacteria,43HEW@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	E	Belongs to the GcvT family	-	-	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
k141_2616_1	1469245.JFBG01000030_gene1547	4.36e-68	221.0	COG0628@1|root,COG0628@2|Bacteria,1MXXU@1224|Proteobacteria,1RQCM@1236|Gammaproteobacteria,1WXT8@135613|Chromatiales	135613|Chromatiales	S	PFAM Uncharacterised protein family UPF0118	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
k141_9398_1	754476.Q7A_1338	1.99e-44	149.0	COG2993@1|root,COG2993@2|Bacteria,1MXEY@1224|Proteobacteria,1RPU6@1236|Gammaproteobacteria,460P4@72273|Thiotrichales	72273|Thiotrichales	C	TIGRFAM cytochrome c oxidase, cbb3-type, subunit II	-	-	-	ko:K00405	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	FixO
k141_9398_2	754476.Q7A_1337	6.55e-47	160.0	COG3278@1|root,COG3278@2|Bacteria,1MU18@1224|Proteobacteria,1RM7I@1236|Gammaproteobacteria,460AT@72273|Thiotrichales	72273|Thiotrichales	C	Belongs to the heme-copper respiratory oxidase family	-	-	1.9.3.1	ko:K00404	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	COX1
k141_5081_1	658187.LDG_8696	5.65e-61	197.0	COG0451@1|root,COG0451@2|Bacteria,1MU7J@1224|Proteobacteria,1RPTA@1236|Gammaproteobacteria,1JDMP@118969|Legionellales	118969|Legionellales	M	Polysaccharide biosynthesis protein	capI	-	5.1.3.6	ko:K08679	ko00520,ko01100,map00520,map01100	-	R01385	RC00289	ko00000,ko00001,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
k141_140_2	159749.E7BWK9	6.22e-207	585.0	COG0459@1|root,KOG0356@2759|Eukaryota,2XBJD@2836|Bacillariophyta	2759|Eukaryota	O	Belongs to the chaperonin (HSP60) family	groL	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009536,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
k141_7504_1	1121374.KB891586_gene2439	5.34e-11	64.7	COG4774@1|root,COG4774@2|Bacteria,1QXWU@1224|Proteobacteria,1T3IF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
k141_6417_1	94624.Bpet2748	3.54e-39	140.0	COG0436@1|root,COG0436@2|Bacteria,1MWS8@1224|Proteobacteria,2VI7S@28216|Betaproteobacteria,3T1HH@506|Alcaligenaceae	28216|Betaproteobacteria	E	Aminotransferase	alaC	-	-	ko:K14261	-	-	-	-	ko00000,ko01000,ko01007	-	-	-	Aminotran_1_2
k141_7028_1	1385519.N801_12760	1.91e-68	221.0	COG0446@1|root,COG0446@2|Bacteria,2GRTN@201174|Actinobacteria,4FFV5@85021|Intrasporangiaceae	201174|Actinobacteria	S	Oxidoreductase	-	-	1.8.5.4	ko:K17218	ko00920,map00920	-	R10152	RC03155	ko00000,ko00001,ko01000	-	-	-	DsrC,Pyr_redox_2
k141_7590_1	1120953.AUBH01000007_gene1692	5.54e-105	320.0	COG0146@1|root,COG0146@2|Bacteria,1QU46@1224|Proteobacteria,1T2DW@1236|Gammaproteobacteria,46AGN@72275|Alteromonadaceae	1236|Gammaproteobacteria	EQ	Hydantoinase B/oxoprolinase	hyuB	-	3.5.2.14	ko:K01474	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydantoinase_B
k141_2095_1	1366046.HIMB11_02734	4.77e-16	74.7	COG1309@1|root,COG1309@2|Bacteria,1MUUY@1224|Proteobacteria,2TUIH@28211|Alphaproteobacteria,3ZGSV@58840|unclassified Rhodobacteraceae	28211|Alphaproteobacteria	K	Transcriptional regulator, TetR family	MA20_04045	-	-	-	-	-	-	-	-	-	-	-	TetR_N,WHG
k141_2095_2	314270.RB2083_580	1.08e-28	107.0	2AS6X@1|root,31HJW@2|Bacteria,1RGYJ@1224|Proteobacteria,2U9UH@28211|Alphaproteobacteria,3ZHNA@58840|unclassified Rhodobacteraceae	28211|Alphaproteobacteria	S	K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit	MA20_04040	-	-	-	-	-	-	-	-	-	-	-	DUF2852
k141_3936_2	998674.ATTE01000001_gene3120	9.76e-54	182.0	COG2987@1|root,COG2987@2|Bacteria,1MU4W@1224|Proteobacteria,1RP89@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate	hutU	GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006547,GO:0006548,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009987,GO:0016054,GO:0016153,GO:0016829,GO:0016835,GO:0016836,GO:0019439,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046395,GO:0046483,GO:0046700,GO:0052803,GO:0052805,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	4.2.1.49	ko:K01712	ko00340,ko01100,map00340,map01100	M00045	R02914	RC00804	ko00000,ko00001,ko00002,ko01000	-	-	-	Urocanase,Urocanase_C,Urocanase_N
k141_2711_1	983548.Krodi_1133	0.000785	48.1	COG2217@1|root,COG2217@2|Bacteria,4NERS@976|Bacteroidetes,1HWUI@117743|Flavobacteriia	976|Bacteroidetes	P	heavy metal translocating P-type ATPase	silP	-	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
k141_5181_1	583355.Caka_2655	6.25e-87	264.0	COG4974@1|root,COG4974@2|Bacteria,46U04@74201|Verrucomicrobia,3K7J0@414999|Opitutae	414999|Opitutae	D	Belongs to the 'phage' integrase family. XerC subfamily	-	-	-	ko:K03733	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
k141_3937_1	2850.Phatr35627	8.37e-39	141.0	2C4NG@1|root,2S7DX@2759|Eukaryota,2XB21@2836|Bacillariophyta	2836|Bacillariophyta	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_8223_1	327079.R9NVJ9	3.73e-62	212.0	COG0843@1|root,COG1622@1|root,KOG4767@2759|Eukaryota,KOG4769@2759|Eukaryota,38FF8@33154|Opisthokonta,3NUKK@4751|Fungi,3UZNV@5204|Basidiomycota,3N583@452284|Ustilaginomycotina	4751|Fungi	C	Cytochrome C oxidase subunit II, transmembrane domain	cox2	GO:0003674,GO:0003824,GO:0004129,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005746,GO:0005751,GO:0006091,GO:0006119,GO:0006123,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009055,GO:0009060,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015002,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015672,GO:0015980,GO:0016020,GO:0016021,GO:0016310,GO:0016491,GO:0016675,GO:0016676,GO:0017144,GO:0019637,GO:0019646,GO:0019693,GO:0019866,GO:0022857,GO:0022890,GO:0022900,GO:0022904,GO:0031090,GO:0031224,GO:0031966,GO:0031967,GO:0031975,GO:0032991,GO:0034220,GO:0034641,GO:0042773,GO:0042775,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044281,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044444,GO:0044446,GO:0044455,GO:0044464,GO:0045277,GO:0045333,GO:0046034,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0055114,GO:0070069,GO:0070469,GO:0071704,GO:0072521,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098798,GO:0098800,GO:0098803,GO:1901135,GO:1901360,GO:1901564,GO:1902600	-	ko:K02261	ko00190,ko01100,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map04260,map04714,map04932,map05010,map05012,map05016	M00154	-	-	ko00000,ko00001,ko00002,ko03029	3.D.4.11,3.D.4.7,3.D.4.8	-	-	COX2,COX2_TM
k141_2712_1	391626.OAN307_c03620	1.41e-77	239.0	COG1177@1|root,COG1177@2|Bacteria,1PVR0@1224|Proteobacteria,2U1TA@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	ABC-type spermidine putrescine transport system, permease component II	-	-	-	ko:K11070	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	BPD_transp_1
k141_4566_2	391616.OA238_c46050	1.2e-199	559.0	COG3328@1|root,COG3328@2|Bacteria,1MU4P@1224|Proteobacteria,2TTAW@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_mut
k141_8841_1	497321.C664_10058	2.56e-66	213.0	COG0162@1|root,COG0162@2|Bacteria,1MVUQ@1224|Proteobacteria,2VHF7@28216|Betaproteobacteria,2KUT9@206389|Rhodocyclales	206389|Rhodocyclales	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	-	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
k141_5182_1	439496.RBY4I_730	6e-62	197.0	COG2801@1|root,COG2801@2|Bacteria,1MVN5@1224|Proteobacteria,2TQK0@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	COG2801 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	HTH_21,rve,rve_3
k141_240_1	1237149.C900_01639	6.76e-96	285.0	COG1309@1|root,COG1309@2|Bacteria,4NQ99@976|Bacteroidetes,47QGN@768503|Cytophagia	976|Bacteroidetes	K	PFAM Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
k141_6420_1	497964.CfE428DRAFT_3367	1.09e-60	203.0	COG3344@1|root,COG3344@2|Bacteria,46UR2@74201|Verrucomicrobia	74201|Verrucomicrobia	L	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	GIIM,RVT_1
k141_3311_1	9555.ENSPANP00000000003	1.15e-49	172.0	COG0843@1|root,KOG4769@2759|Eukaryota,38JQ7@33154|Opisthokonta,3BGCX@33208|Metazoa,3CVN2@33213|Bilateria,484GM@7711|Chordata,490P8@7742|Vertebrata,3JD2N@40674|Mammalia,35MKX@314146|Euarchontoglires,4MP2D@9443|Primates,35ZXE@314294|Cercopithecoidea	33208|Metazoa	Q	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B	COX1	GO:0003674,GO:0003824,GO:0004129,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005746,GO:0005750,GO:0005751,GO:0006091,GO:0006119,GO:0006123,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0006950,GO:0006979,GO:0007275,GO:0007399,GO:0007417,GO:0007420,GO:0007568,GO:0008150,GO:0008152,GO:0008324,GO:0009055,GO:0009060,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009628,GO:0009987,GO:0010033,GO:0010035,GO:0010038,GO:0015002,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015672,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0016310,GO:0016491,GO:0016675,GO:0016676,GO:0017144,GO:0019637,GO:0019646,GO:0019693,GO:0019866,GO:0021549,GO:0022037,GO:0022857,GO:0022890,GO:0022900,GO:0022904,GO:0030902,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0032501,GO:0032502,GO:0032991,GO:0034220,GO:0034641,GO:0042221,GO:0042773,GO:0042775,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044281,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044444,GO:0044446,GO:0044455,GO:0044464,GO:0045275,GO:0045277,GO:0045333,GO:0046034,GO:0046483,GO:0046686,GO:0046688,GO:0048513,GO:0048731,GO:0048856,GO:0050896,GO:0051179,GO:0051234,GO:0051597,GO:0051602,GO:0055085,GO:0055086,GO:0055114,GO:0060322,GO:0070069,GO:0070469,GO:0071704,GO:0072521,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098798,GO:0098800,GO:0098803,GO:1901135,GO:1901360,GO:1901564,GO:1902494,GO:1902600,GO:1990204	1.9.3.1	ko:K02256	ko00190,ko01100,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map04260,map04714,map04932,map05010,map05012,map05016	M00154	-	-	ko00000,ko00001,ko00002,ko01000,ko03029	3.D.4.11,3.D.4.7,3.D.4.8	-	-	COX1,COX2
k141_1480_1	1380387.JADM01000008_gene947	1.29e-17	79.0	COG3108@1|root,COG3108@2|Bacteria,1QDAN@1224|Proteobacteria	1224|Proteobacteria	S	peptidase M15A	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M15_3
k141_241_1	292564.Cyagr_1154	1.68e-66	217.0	COG1282@1|root,COG1282@2|Bacteria,1G2AX@1117|Cyanobacteria,22RXF@167375|Cyanobium	1117|Cyanobacteria	C	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane	pntB	-	1.6.1.2	ko:K00325	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	PNTB
k141_2099_1	501479.ACNW01000060_gene2561	7.85e-88	281.0	COG2183@1|root,COG2183@2|Bacteria,1MUA7@1224|Proteobacteria,2TTSC@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	Transcriptional accessory protein	tex	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009314,GO:0009628,GO:0010212,GO:0044424,GO:0044444,GO:0044464,GO:0050896	-	ko:K06959	-	-	-	-	ko00000	-	-	-	HHH_3,S1,Tex_N,Tex_YqgF
k141_866_1	1121912.AUHD01000001_gene2690	7.17e-55	184.0	COG2979@1|root,COG2979@2|Bacteria,4PKCN@976|Bacteroidetes,1IJ7M@117743|Flavobacteriia	976|Bacteroidetes	S	LETM1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	LETM1
k141_866_2	1121007.AUML01000003_gene2564	4.39e-07	47.8	COG4807@1|root,COG4807@2|Bacteria,4NSYM@976|Bacteroidetes,1I3ZP@117743|Flavobacteriia,2YJX5@290174|Aquimarina	976|Bacteroidetes	S	Protein of unknown function (DUF1456)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1456
k141_4569_1	1535422.ND16A_0740	2.25e-90	279.0	COG3119@1|root,COG3119@2|Bacteria,1MUJH@1224|Proteobacteria,1RN2V@1236|Gammaproteobacteria,2Q7EB@267889|Colwelliaceae	1236|Gammaproteobacteria	P	PFAM sulfatase	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
k141_1481_1	196367.JNFG01000202_gene2638	2.64e-129	385.0	COG1960@1|root,COG1960@2|Bacteria,1MU20@1224|Proteobacteria,2VGZD@28216|Betaproteobacteria,1K5NT@119060|Burkholderiaceae	28216|Betaproteobacteria	I	Acyl-CoA dehydrogenase N terminal	-	-	-	ko:K20035	ko00920,map00920	-	R11130	RC03363	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_C,Acyl-CoA_dh_M,Acyl-CoA_dh_N,AcylCoA_DH_N
k141_5185_2	314275.MADE_1018360	1.71e-15	75.5	COG0568@1|root,COG0568@2|Bacteria,1MVWR@1224|Proteobacteria,1RMFR@1236|Gammaproteobacteria,464GZ@72275|Alteromonadaceae	1236|Gammaproteobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes	rpoH	GO:0000150,GO:0000976,GO:0000984,GO:0000985,GO:0000988,GO:0000990,GO:0001017,GO:0001046,GO:0001047,GO:0001067,GO:0001121,GO:0001130,GO:0001131,GO:0001140,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006310,GO:0006351,GO:0006352,GO:0006355,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009009,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016020,GO:0016070,GO:0016987,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031421,GO:0032774,GO:0032991,GO:0032993,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0045893,GO:0045935,GO:0046483,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:0140097,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2000142,GO:2001141	-	ko:K03089	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r4
k141_8844_1	1366046.HIMB11_02971	3.43e-93	299.0	COG0403@1|root,COG1003@1|root,COG0403@2|Bacteria,COG1003@2|Bacteria,1MUDP@1224|Proteobacteria,2TSFF@28211|Alphaproteobacteria,3ZH27@58840|unclassified Rhodobacteraceae	28211|Alphaproteobacteria	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvP	-	1.4.4.2	ko:K00281,ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko00002,ko01000	-	-	-	Aminotran_5,GDC-P
k141_868_2	1300345.LF41_2520	4.27e-33	123.0	COG3485@1|root,COG3485@2|Bacteria,1MUYX@1224|Proteobacteria,1RQHU@1236|Gammaproteobacteria,1X3TP@135614|Xanthomonadales	135614|Xanthomonadales	Q	protocatechuate 3,4-dioxygenase	pcaH	-	1.13.11.3	ko:K00449	ko00362,ko00624,ko01100,ko01120,ko01220,map00362,map00624,map01100,map01120,map01220	-	R01631,R03549	RC00388,RC00953	br01602,ko00000,ko00001,ko01000	-	-	-	Dioxygenase_C,PCDO_beta_N
k141_2715_2	13037.EHJ65566	1.23e-33	129.0	KOG1075@1|root,KOG1075@2759|Eukaryota,39TZY@33154|Opisthokonta,3BI15@33208|Metazoa,3CYKV@33213|Bilateria,420TT@6656|Arthropoda,3SQX5@50557|Insecta,449FF@7088|Lepidoptera	33208|Metazoa	J	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	2.3.1.15,2.4.2.29	ko:K13506,ko:K15407	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R03789,R09380,R10209	RC00004,RC00039,RC00041,RC00063	ko00000,ko00001,ko00002,ko01000,ko01004,ko03016	-	-	-	Exo_endo_phos_2,RVT_1
k141_3314_1	2850.Phatr29887	5.12e-38	142.0	COG1488@1|root,KOG2511@2759|Eukaryota,2XAYD@2836|Bacillariophyta	2836|Bacillariophyta	H	nicotinate phosphoribosyltransferase activity	-	-	6.3.4.21	ko:K00763	ko00760,ko01100,map00760,map01100	-	R01724	RC00033	ko00000,ko00001,ko01000	-	-	-	NAPRTase
k141_8228_1	1089550.ATTH01000001_gene1196	6.99e-65	216.0	COG2225@1|root,COG2225@2|Bacteria,4NF5H@976|Bacteroidetes,1FJVN@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	C	Malate synthase	aceB	-	2.3.3.9	ko:K01638	ko00620,ko00630,ko01100,ko01110,ko01120,ko01200,map00620,map00630,map01100,map01110,map01120,map01200	M00012	R00472	RC00004,RC00308,RC02747	ko00000,ko00001,ko00002,ko01000	-	-	-	Malate_synthase
k141_1482_1	391593.RCCS2_13664	6.25e-29	113.0	COG0541@1|root,COG0541@2|Bacteria,1MVIA@1224|Proteobacteria,2TQSW@28211|Alphaproteobacteria,2P19X@2433|Roseobacter	28211|Alphaproteobacteria	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components	ffh	-	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
k141_1482_2	391593.RCCS2_13644	1.2e-45	148.0	COG1605@1|root,COG1605@2|Bacteria,1MZTQ@1224|Proteobacteria,2UCMC@28211|Alphaproteobacteria,2P38J@2433|Roseobacter	28211|Alphaproteobacteria	E	COG1605 Chorismate mutase	tyrA	-	5.4.99.5	ko:K04092	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R01715	RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	CM_2
k141_8229_1	412965.COSY_0882	3.45e-08	56.2	COG0471@1|root,COG0471@2|Bacteria,1MU0K@1224|Proteobacteria,1RMI1@1236|Gammaproteobacteria,1J8SM@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	P	Citrate transporter	sac1	-	-	-	-	-	-	-	-	-	-	-	CitMHS,TrkA_C
k141_2103_1	395493.BegalDRAFT_1391	1.25e-65	205.0	COG0386@1|root,COG0386@2|Bacteria,1RD1R@1224|Proteobacteria,1S425@1236|Gammaproteobacteria,4610J@72273|Thiotrichales	72273|Thiotrichales	O	Belongs to the glutathione peroxidase family	-	-	-	-	-	-	-	-	-	-	-	-	GSHPx
k141_3799_1	1316936.K678_16600	2.85e-50	181.0	COG0642@1|root,COG1352@1|root,COG2201@1|root,COG1352@2|Bacteria,COG2201@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,2TWP9@28211|Alphaproteobacteria,2JYV4@204441|Rhodospirillales	204441|Rhodospirillales	T	Protein-glutamate methylesterase	-	-	2.1.1.80,3.1.1.61	ko:K13924	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,CheR,CheR_N,GerE,HATPase_c,HisKA,PAS_10,Response_reg
k141_5042_1	1121440.AUMA01000011_gene2420	1.27e-16	76.6	2B047@1|root,31SEM@2|Bacteria,1RHZY@1224|Proteobacteria,42V93@68525|delta/epsilon subdivisions,2WVVI@28221|Deltaproteobacteria,2MCS3@213115|Desulfovibrionales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_103_1	35128.Thapsdraft1720	9.1e-126	377.0	COG0465@1|root,KOG0731@2759|Eukaryota,2XEEJ@2836|Bacillariophyta	2836|Bacillariophyta	O	Acts as a processive, ATP-dependent zinc metallopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	AAA,Peptidase_M41
k141_8716_1	991905.SL003B_2510	1.88e-42	158.0	COG0847@1|root,COG2905@1|root,COG0847@2|Bacteria,COG2905@2|Bacteria,1MW8U@1224|Proteobacteria,2TRZC@28211|Alphaproteobacteria,4BQ0X@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	LT	Putative nucleotidyltransferase substrate binding domain	-	-	2.7.7.7	ko:K02342,ko:K07182	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	CBS,DUF294,DUF294_C,RNase_T
k141_5655_1	545264.KB898751_gene2622	1.26e-102	315.0	COG0504@1|root,COG0504@2|Bacteria,1MUIT@1224|Proteobacteria,1RM92@1236|Gammaproteobacteria,1WWJ8@135613|Chromatiales	135613|Chromatiales	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_synth_N,GATase
k141_2576_1	644107.SL1157_2215	6.8e-30	112.0	COG3638@1|root,COG3638@2|Bacteria,1MVE9@1224|Proteobacteria,2TRR3@28211|Alphaproteobacteria,4NB95@97050|Ruegeria	28211|Alphaproteobacteria	P	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system	phnC	-	3.6.3.28	ko:K02041	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.9	-	-	ABC_tran
k141_2576_2	981384.AEYW01000004_gene1805	7.72e-39	139.0	COG3221@1|root,COG3221@2|Bacteria,1MWFF@1224|Proteobacteria,2TUB4@28211|Alphaproteobacteria,4NB06@97050|Ruegeria	28211|Alphaproteobacteria	P	ABC transporter, phosphonate, periplasmic substrate-binding protein	-	-	-	ko:K02044	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	Phosphonate-bd
k141_4430_2	1188256.BASI01000001_gene675	3.87e-19	84.0	2CD0I@1|root,32RWS@2|Bacteria,1N0MC@1224|Proteobacteria,2U9CM@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Domain of unknown function (DUF4399)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4399
k141_726_1	1280380.KR100_07520	8.81e-99	313.0	COG0542@1|root,COG0542@2|Bacteria,1G0ZH@1117|Cyanobacteria,1GYXV@1129|Synechococcus	1117|Cyanobacteria	O	Belongs to the ClpA ClpB family	clpC	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
k141_1348_1	391165.GbCGDNIH1_0566	3.71e-39	134.0	COG0094@1|root,COG0094@2|Bacteria,1MUU9@1224|Proteobacteria,2TQPF@28211|Alphaproteobacteria,2JRV3@204441|Rhodospirillales	204441|Rhodospirillales	J	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits	rplE	-	-	ko:K02931	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L5,Ribosomal_L5_C
k141_1348_2	743836.AYNA01000109_gene2126	2.4e-37	127.0	COG0199@1|root,COG0199@2|Bacteria,1MZDT@1224|Proteobacteria,2UC01@28211|Alphaproteobacteria,36YQ4@31993|Methylocystaceae	28211|Alphaproteobacteria	J	Ribosomal protein S14p/S29e	rpsN	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02954	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S14
k141_5656_1	760192.Halhy_5180	7.16e-09	62.4	COG3829@1|root,COG3829@2|Bacteria,4PM5Y@976|Bacteroidetes,1IP1G@117747|Sphingobacteriia	976|Bacteroidetes	KT	COGs COG3604 Transcriptional regulator containing GAF AAA-type ATPase and DNA binding domains	-	-	-	ko:K15836	-	-	-	-	ko00000,ko03000	-	-	-	GAF,GAF_2,HTH_8,PAS_9,Response_reg,Sigma54_activat,cNMP_binding
k141_8102_1	257310.BB1104	2.46e-17	84.0	COG4638@1|root,COG4638@2|Bacteria,1MWXW@1224|Proteobacteria,2VJT8@28216|Betaproteobacteria,3T4UT@506|Alcaligenaceae	28216|Betaproteobacteria	P	Ring hydroxylating alpha subunit (catalytic domain)	-	-	-	-	-	-	-	-	-	-	-	-	Rieske,Ring_hydroxyl_A
k141_8102_3	52598.EE36_11274	5.27e-19	85.9	COG0154@1|root,COG0154@2|Bacteria,1MWRI@1224|Proteobacteria,2TTJU@28211|Alphaproteobacteria,3ZVY7@60136|Sulfitobacter	28211|Alphaproteobacteria	J	Amidase	-	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
k141_9363_1	1178825.ALIH01000013_gene559	1.44e-116	347.0	COG0055@1|root,COG0055@2|Bacteria,4NF1Q@976|Bacteroidetes,1HWM2@117743|Flavobacteriia	976|Bacteroidetes	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
k141_3802_1	1121101.HMPREF1532_01927	2.7e-74	246.0	COG1472@1|root,COG1472@2|Bacteria,4NE90@976|Bacteroidetes,2FMCU@200643|Bacteroidia,4AK8A@815|Bacteroidaceae	976|Bacteroidetes	G	glycosyl hydrolase, family 3	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
k141_4433_1	1380600.AUYN01000001_gene2326	7.41e-66	207.0	2C0G9@1|root,310GM@2|Bacteria,4NHU0@976|Bacteroidetes,1HYZT@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_9364_1	1121875.KB907546_gene2495	1.32e-103	328.0	28HKI@1|root,2Z7VC@2|Bacteria,4NFS2@976|Bacteroidetes,1HYBU@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_2579_1	216596.RL3171	2.23e-20	91.7	COG2020@1|root,COG2020@2|Bacteria,1R7G6@1224|Proteobacteria,2VG1Y@28211|Alphaproteobacteria,4BFJ4@82115|Rhizobiaceae	28211|Alphaproteobacteria	O	Isoprenylcysteine carboxyl methyltransferase (ICMT) family	-	-	-	-	-	-	-	-	-	-	-	-	ICMT,PEMT
k141_1351_1	1198232.CYCME_1842	2.27e-09	56.6	COG2993@1|root,COG2993@2|Bacteria,1MXEY@1224|Proteobacteria,1RPU6@1236|Gammaproteobacteria,460P4@72273|Thiotrichales	72273|Thiotrichales	C	TIGRFAM cytochrome c oxidase, cbb3-type, subunit II	-	-	-	ko:K00405	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	FixO
k141_1351_2	395493.BegalDRAFT_0212	5.89e-56	188.0	COG3278@1|root,COG3278@2|Bacteria,1MU18@1224|Proteobacteria,1RM7I@1236|Gammaproteobacteria,460AT@72273|Thiotrichales	72273|Thiotrichales	C	Belongs to the heme-copper respiratory oxidase family	-	-	1.9.3.1	ko:K00404	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	COX1
k141_107_1	879212.DespoDRAFT_02688	8.94e-37	137.0	COG1013@1|root,COG1013@2|Bacteria,1R5BF@1224|Proteobacteria,42MRV@68525|delta/epsilon subdivisions,2WK9C@28221|Deltaproteobacteria,2MJ4G@213118|Desulfobacterales	28221|Deltaproteobacteria	C	TIGRFAM pyruvate ferredoxin flavodoxin oxidoreductase, beta subunit	porB	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFO_beta_C,TPP_enzyme_C
k141_7476_1	102232.GLO73106DRAFT_00034260	3.36e-33	117.0	COG0211@1|root,COG0211@2|Bacteria,1G7RW@1117|Cyanobacteria	1117|Cyanobacteria	J	Belongs to the bacterial ribosomal protein bL27 family	rpmA	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02899	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27
k141_7476_2	159749.E7BWK0	1.3e-292	826.0	COG0653@1|root,2QS7I@2759|Eukaryota,2XADP@2836|Bacillariophyta	2759|Eukaryota	U	Protein translocase subunit secA	secA	-	-	-	-	-	-	-	-	-	-	-	SecA_DEAD,SecA_PP_bind,SecA_SW
k141_3186_3	159749.E7BWM5	8.83e-83	246.0	COG0197@1|root,KOG3422@2759|Eukaryota	2759|Eukaryota	J	rRNA binding	MRPL16	GO:0000048,GO:0000313,GO:0000314,GO:0000315,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0003824,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005759,GO:0005761,GO:0005762,GO:0005763,GO:0005829,GO:0005840,GO:0006412,GO:0006414,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009507,GO:0009526,GO:0009532,GO:0009536,GO:0009570,GO:0009941,GO:0009987,GO:0010467,GO:0015934,GO:0015935,GO:0016020,GO:0016043,GO:0016740,GO:0016746,GO:0016755,GO:0019538,GO:0019843,GO:0019866,GO:0022411,GO:0022625,GO:0022626,GO:0031090,GO:0031966,GO:0031967,GO:0031974,GO:0031975,GO:0032543,GO:0032984,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044429,GO:0044434,GO:0044435,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070013,GO:0070125,GO:0070126,GO:0071704,GO:0071840,GO:0097159,GO:0098798,GO:0140053,GO:0140096,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02874,ko:K02878,ko:K10756	ko03010,ko03030,ko03420,ko03430,map03010,map03030,map03420,map03430	M00178,M00179,M00289,M00295	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03032,ko03036,ko03400	-	-	-	Ribosomal_L16
k141_3186_4	159749.E7BWM4	6.07e-102	300.0	COG0092@1|root,2QV63@2759|Eukaryota	2759|Eukaryota	J	structural constituent of ribosome	rps3	GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009295,GO:0009507,GO:0009526,GO:0009532,GO:0009536,GO:0009570,GO:0009941,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022626,GO:0022627,GO:0031967,GO:0031975,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02982	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KH_2,Ribosomal_S3_C
k141_3186_5	159749.E7BWM3	5.74e-67	206.0	COG0091@1|root,KOG1711@2759|Eukaryota	2759|Eukaryota	J	structural constituent of ribosome	rpl22	GO:0000313,GO:0000315,GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005761,GO:0005762,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009507,GO:0009526,GO:0009532,GO:0009536,GO:0009570,GO:0009941,GO:0009987,GO:0010467,GO:0015934,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0031967,GO:0031974,GO:0031975,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044429,GO:0044434,GO:0044435,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070013,GO:0071704,GO:0098798,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02890,ko:K02982	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L22
k141_5659_1	59538.XP_005977360.1	9.88e-81	266.0	COG0265@1|root,COG0465@1|root,KOG0731@2759|Eukaryota,KOG1320@2759|Eukaryota,38FRA@33154|Opisthokonta,3BEA7@33208|Metazoa,3CR69@33213|Bilateria,48125@7711|Chordata,492S9@7742|Vertebrata,3JC82@40674|Mammalia,4J3RZ@91561|Cetartiodactyla	33208|Metazoa	O	AFG3-like protein	-	-	-	ko:K08956	-	-	-	-	ko00000,ko01000,ko01002,ko03110	-	-	-	AAA,Peptidase_M41
k141_8104_1	1169143.KB911055_gene2513	1.29e-96	293.0	COG3547@1|root,COG3547@2|Bacteria,1MUER@1224|Proteobacteria,2VJ5H@28216|Betaproteobacteria,1K2CZ@119060|Burkholderiaceae	28216|Betaproteobacteria	L	transposase IS116 IS110 IS902 family	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k141_1967_1	1121875.KB907560_gene527	9.46e-47	152.0	2DMHR@1|root,32RMI@2|Bacteria,4NS7M@976|Bacteroidetes,1I3YS@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_109_1	717785.HYPMC_3593	3.91e-99	303.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,2TQR1@28211|Alphaproteobacteria,3N666@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	C	Belongs to the aldehyde dehydrogenase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldedh
k141_3187_1	713586.KB900536_gene1176	1.14e-109	351.0	COG0086@1|root,COG0086@2|Bacteria,1MU3M@1224|Proteobacteria,1RPYH@1236|Gammaproteobacteria,1WVVI@135613|Chromatiales	135613|Chromatiales	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	-	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
k141_6282_1	35128.Thapsdraft1267	1.49e-77	263.0	COG0085@1|root,KOG0214@2759|Eukaryota,2XEM3@2836|Bacillariophyta	2836|Bacillariophyta	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	-	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009536,GO:0030880,GO:0032991,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0061695,GO:1902494,GO:1990234	-	-	-	-	-	-	-	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
k141_8105_1	204773.HEAR0284	2.02e-10	63.2	COG0277@1|root,COG0277@2|Bacteria,1MU6Y@1224|Proteobacteria,2VH8M@28216|Betaproteobacteria,472AD@75682|Oxalobacteraceae	28216|Betaproteobacteria	C	Glycolate oxidase subunit GlcD	glcD	-	1.1.2.4,1.1.3.15,1.1.5.12	ko:K00102,ko:K00104,ko:K03777	ko00620,ko00630,ko01100,ko01110,ko01120,ko01130,map00620,map00630,map01100,map01110,map01120,map01130	-	R00197,R00475,R00704,R11591	RC00042,RC00044	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
k141_6894_1	237727.NAP1_04995	2.81e-36	136.0	COG1752@1|root,COG1752@2|Bacteria,1N5SK@1224|Proteobacteria,2UP09@28211|Alphaproteobacteria,2K9EB@204457|Sphingomonadales	204457|Sphingomonadales	S	Domain of unknown function (DUF3336)	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	DUF3336,Patatin
k141_6894_2	1159870.KB907784_gene3472	7.36e-22	94.7	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,2VHAT@28216|Betaproteobacteria,3T1C9@506|Alcaligenaceae	28216|Betaproteobacteria	IQ	Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II	-	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
k141_3188_1	644107.SL1157_1794	1.84e-77	246.0	COG4176@1|root,COG4176@2|Bacteria,1MUM4@1224|Proteobacteria,2TRF1@28211|Alphaproteobacteria,4NBVN@97050|Ruegeria	28211|Alphaproteobacteria	E	ABC transporter, permease protein	-	-	-	ko:K02001	ko02010,map02010	M00208	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	BPD_transp_1
k141_7478_1	1121939.L861_14220	7.18e-119	352.0	COG0141@1|root,COG0141@2|Bacteria,1MUUF@1224|Proteobacteria,1RPDZ@1236|Gammaproteobacteria,1XN3H@135619|Oceanospirillales	135619|Oceanospirillales	E	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine	-	-	1.1.1.308	ko:K15509	-	-	-	-	ko00000,ko01000	-	-	-	Histidinol_dh
k141_8721_1	1229909.NSED_08930	6.02e-34	123.0	arCOG10597@1|root,arCOG10597@2157|Archaea	2157|Archaea	O	serine-type endopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_8721_2	1229909.NSED_08935	1.49e-40	141.0	COG3794@1|root,arCOG02926@2157|Archaea	2157|Archaea	C	PFAM blue (type 1) copper domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind
k141_6895_1	748658.KB907312_gene1825	3.44e-37	143.0	COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,1RZDK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
k141_5662_1	83219.PM02_17320	2.31e-99	294.0	COG0411@1|root,COG0411@2|Bacteria,1MX51@1224|Proteobacteria,2VEYC@28211|Alphaproteobacteria,3ZVTF@60136|Sulfitobacter	28211|Alphaproteobacteria	E	Branched-chain amino acid ATP-binding cassette transporter	MA20_09940	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
k141_731_1	640081.Dsui_0846	7.73e-18	83.2	COG0445@1|root,COG0445@2|Bacteria,1MU6F@1224|Proteobacteria,2VIGG@28216|Betaproteobacteria,2KUAA@206389|Rhodocyclales	206389|Rhodocyclales	D	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34	gidA	-	-	ko:K03495	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko03016,ko03036	-	-	-	GIDA,GIDA_assoc
k141_731_2	439375.Oant_3596	3.59e-08	57.0	COG4166@1|root,COG4166@2|Bacteria,1P91R@1224|Proteobacteria,2TT6P@28211|Alphaproteobacteria,1J1SX@118882|Brucellaceae	28211|Alphaproteobacteria	E	Bacterial extracellular solute-binding proteins, family 5 Middle	oppA	-	-	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	SBP_bac_5
k141_4437_1	391598.FBBAL38_08949	5.88e-51	164.0	COG0757@1|root,COG0757@2|Bacteria,4NNHU@976|Bacteroidetes,1I20S@117743|Flavobacteriia	976|Bacteroidetes	E	Catalyzes a trans-dehydration via an enolate intermediate	aroQ	-	4.2.1.10	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03084	RC00848	ko00000,ko00001,ko00002,ko01000	-	-	-	DHquinase_II
k141_3807_1	2903.EOD12544	1.92e-24	101.0	COG3310@1|root,2SXKE@2759|Eukaryota	2903.EOD12544|-	S	Protein of unknown function (DUF1415)	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_111_1	391616.OA238_c00440	1.31e-21	92.0	COG0191@1|root,COG0191@2|Bacteria,1MURX@1224|Proteobacteria,2TSAD@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	Fructose-bisphosphate aldolase, class II, Calvin cycle subtype	cbbA	-	4.1.2.13	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167,M00344,M00345	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	F_bP_aldolase
k141_1355_1	1122614.JHZF01000013_gene3786	2.89e-27	106.0	COG0115@1|root,COG0115@2|Bacteria,1MVAT@1224|Proteobacteria,2TR7R@28211|Alphaproteobacteria,2PCH5@252301|Oceanicola	28211|Alphaproteobacteria	EH	Amino-transferase class IV	dat	-	2.6.1.21	ko:K00824	ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100	-	R01148,R01582,R02459,R02851,R02924,R05053	RC00006,RC00008,RC00025	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_4
k141_1355_2	1121479.AUBS01000027_gene455	2.8e-73	229.0	COG4948@1|root,COG4948@2|Bacteria,1MW76@1224|Proteobacteria,2TR16@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	Belongs to the mandelate racemase muconate lactonizing enzyme family	ycjG	GO:0003674,GO:0003824,GO:0016853,GO:0016854,GO:0016855	5.1.1.20	ko:K19802	-	-	R10938	RC03309	ko00000,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
k141_1969_1	443218.AS9A_4280	1.01e-20	95.5	COG2826@1|root,COG2826@2|Bacteria,2GMZX@201174|Actinobacteria,2346K@1762|Mycobacteriaceae	201174|Actinobacteria	L	PFAM Integrase	-	-	-	-	-	-	-	-	-	-	-	-	HTH_32,HTH_38,rve
k141_6998_3	1174528.JH992898_gene2300	3.33e-27	105.0	COG0097@1|root,COG0097@2|Bacteria,1G4ZT@1117|Cyanobacteria,1JHYC@1189|Stigonemataceae	1117|Cyanobacteria	J	Ribosomal protein L6	rpl6	GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02933	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L6
k141_5151_1	1385515.N791_08310	1.8e-42	150.0	COG1475@1|root,COG1475@2|Bacteria,1MW2E@1224|Proteobacteria,1RN65@1236|Gammaproteobacteria,1X3IJ@135614|Xanthomonadales	135614|Xanthomonadales	K	Belongs to the ParB family	parB	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
k141_5152_1	571166.KI421509_gene4104	2.25e-64	210.0	COG2239@1|root,COG2239@2|Bacteria,1MW24@1224|Proteobacteria,2U4XB@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	MgtE intracellular N domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,MgtE,MgtE_N
k141_9465_1	391593.RCCS2_03654	1.02e-113	332.0	COG1494@1|root,COG1494@2|Bacteria,1MUB1@1224|Proteobacteria,2TSPE@28211|Alphaproteobacteria,2P2IM@2433|Roseobacter	28211|Alphaproteobacteria	G	COG1494 Fructose-1,6-bisphosphatase sedoheptulose 1,7-bisphosphatase and related proteins	glpX	-	3.1.3.11,3.1.3.37	ko:K02446,ko:K11532	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00165,M00167	R00762,R01845,R04780	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FBPase_glpX
k141_6999_1	398578.Daci_3352	1.75e-51	184.0	COG2010@1|root,COG4993@1|root,COG2010@2|Bacteria,COG4993@2|Bacteria,1MUQX@1224|Proteobacteria,2VHVH@28216|Betaproteobacteria,4AAF0@80864|Comamonadaceae	28216|Betaproteobacteria	C	Pyrrolo-quinoline quinone	exaA1	-	1.1.2.9,1.1.9.1	ko:K17760,ko:K20936	-	-	-	-	ko00000,ko01000	-	-	-	Cytochrome_CBB3,PQQ
k141_835_1	1123399.AQVE01000009_gene3123	4.58e-51	168.0	COG2878@1|root,COG2878@2|Bacteria,1MUWU@1224|Proteobacteria,1RNSJ@1236|Gammaproteobacteria,460FE@72273|Thiotrichales	72273|Thiotrichales	C	Part of a membrane complex involved in electron transport	-	-	-	ko:K03616	-	-	-	-	ko00000	-	-	-	FeS,Fer4_21
k141_835_2	765912.Thimo_0962	3.06e-19	89.0	COG4656@1|root,COG4656@2|Bacteria,1QTUI@1224|Proteobacteria,1RMIM@1236|Gammaproteobacteria,1WWSK@135613|Chromatiales	135613|Chromatiales	C	Part of a membrane complex involved in electron transport	-	-	-	ko:K03615	-	-	-	-	ko00000	-	-	-	Complex1_51K,Fer4_10,Fer4_7,Fer4_8,RnfC_N,SLBB
k141_2066_1	1122135.KB893134_gene3919	1.64e-17	82.4	COG3660@1|root,COG3660@2|Bacteria,1R70U@1224|Proteobacteria,2TQWV@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	Nucleoside-diphosphate-sugar epimerase	-	-	-	ko:K07276	-	-	-	-	ko00000	-	-	-	Mito_fiss_Elm1
k141_2066_2	1224746.B932_2389	2.22e-14	71.2	COG0583@1|root,COG0583@2|Bacteria,1MV5N@1224|Proteobacteria,2TRAX@28211|Alphaproteobacteria,2JPCC@204441|Rhodospirillales	204441|Rhodospirillales	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
k141_8809_1	1380391.JIAS01000011_gene4815	1.66e-23	96.7	COG0500@1|root,COG2226@2|Bacteria,1PHAK@1224|Proteobacteria,2V856@28211|Alphaproteobacteria,2JY4W@204441|Rhodospirillales	204441|Rhodospirillales	Q	Mycolic acid cyclopropane synthetase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
k141_8809_2	1446473.JHWH01000010_gene767	8.72e-06	50.4	COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,2TQMJ@28211|Alphaproteobacteria,2PWCI@265|Paracoccus	28211|Alphaproteobacteria	E	Belongs to the ABC transporter superfamily	-	-	-	ko:K02052	ko02024,map02024	M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11	-	-	ABC_tran,TOBE_2
k141_1444_1	331869.BAL199_02564	9.13e-56	183.0	COG1077@1|root,COG1077@2|Bacteria,1MUMW@1224|Proteobacteria,2TTQ2@28211|Alphaproteobacteria,4BPMK@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	D	TIGRFAM cell shape determining protein, MreB Mrl family	mreB	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
k141_4536_1	89187.ISM_10685	4.1e-25	102.0	COG0626@1|root,COG0626@2|Bacteria,1MU57@1224|Proteobacteria,2TW14@28211|Alphaproteobacteria,46Q1G@74030|Roseovarius	28211|Alphaproteobacteria	E	COG0626 Cystathionine beta-lyases cystathionine gamma-synthases	metB	-	2.5.1.48	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017	R00999,R01288,R02508,R03217,R03260,R04944,R04945,R04946	RC00020,RC00056,RC00069,RC00420,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000	-	-	-	Cys_Met_Meta_PP
k141_4536_2	571166.KI421509_gene1647	2.93e-31	113.0	COG2236@1|root,COG2236@2|Bacteria,1MWNE@1224|Proteobacteria,2TUXK@28211|Alphaproteobacteria	28211|Alphaproteobacteria	F	Acts on guanine, xanthine and to a lesser extent hypoxanthine	gpt	-	2.4.2.22	ko:K00769	ko00230,ko01100,ko01110,map00230,map01100,map01110	-	R01229,R02142	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
k141_6388_1	247639.MGP2080_04950	2.57e-54	185.0	COG3202@1|root,COG3202@2|Bacteria,1MVP5@1224|Proteobacteria,1RNY6@1236|Gammaproteobacteria,1JAB2@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	COG3202 ATP ADP translocase	-	-	-	ko:K03301	-	-	-	-	ko00000	2.A.12	-	-	MFS_1,TLC
k141_7561_1	349163.Acry_1610	1.26e-29	115.0	COG0026@1|root,COG0026@2|Bacteria,1MU70@1224|Proteobacteria,2TRSV@28211|Alphaproteobacteria,2JPSW@204441|Rhodospirillales	204441|Rhodospirillales	F	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)	purK	-	6.3.4.18	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07404	RC01927	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp
k141_7561_2	269796.Rru_A1050	2.44e-49	161.0	COG0041@1|root,COG0041@2|Bacteria,1RCWJ@1224|Proteobacteria,2U58D@28211|Alphaproteobacteria,2JRTF@204441|Rhodospirillales	204441|Rhodospirillales	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purE	-	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC
k141_5153_1	1266925.JHVX01000004_gene1189	2.31e-22	92.8	COG2945@1|root,COG2945@2|Bacteria,1MUDY@1224|Proteobacteria,2VJ8M@28216|Betaproteobacteria,372ZS@32003|Nitrosomonadales	28216|Betaproteobacteria	S	hydrolase of the alpha beta superfamily	-	-	-	ko:K07018	-	-	-	-	ko00000	-	-	-	Hydrolase_4,Peptidase_S15
k141_5153_2	85643.Tmz1t_2676	0.000142	44.3	COG4992@1|root,COG4992@2|Bacteria,1MV3C@1224|Proteobacteria,2VHEB@28216|Betaproteobacteria,2KUN2@206389|Rhodocyclales	206389|Rhodocyclales	E	acetylornithine aminotransferase	argD	-	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
k141_7000_1	1408418.JNJH01000012_gene3537	1.1e-70	236.0	COG1529@1|root,COG1529@2|Bacteria,1MUEA@1224|Proteobacteria,2TQMW@28211|Alphaproteobacteria,2JZI6@204441|Rhodospirillales	204441|Rhodospirillales	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
k141_4715_1	744980.TRICHSKD4_3485	3.12e-12	66.2	COG0493@1|root,COG0493@2|Bacteria,1MU2H@1224|Proteobacteria,2TQK5@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases	preT	-	1.3.1.1	ko:K17722	ko00240,ko00410,ko00770,ko01100,map00240,map00410,map00770,map01100	M00046	R00977,R01414,R11026	RC00072,RC00123	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4_20,Pyr_redox_2
k141_4715_2	1238182.C882_0551	4.5e-67	215.0	COG0167@1|root,COG1146@1|root,COG0167@2|Bacteria,COG1146@2|Bacteria,1MXER@1224|Proteobacteria,2TSPK@28211|Alphaproteobacteria,2JQPY@204441|Rhodospirillales	204441|Rhodospirillales	CF	4Fe-4S dicluster domain	-	-	1.3.1.1	ko:K17723	ko00240,ko00410,ko00770,ko01100,map00240,map00410,map00770,map01100	M00046	R00977,R01414,R11026	RC00072,RC00123	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh,Fer4_21
k141_8968_1	391626.OAN307_c43440	2.22e-96	291.0	COG3677@1|root,COG3677@2|Bacteria,1REPF@1224|Proteobacteria,2U8CB@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	ISXO2-like transposase domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS1595,Zn_Tnp_IS1595
k141_2250_1	57918.XP_004298683.1	5.18e-39	139.0	COG0048@1|root,COG0459@1|root,KOG0356@2759|Eukaryota,KOG1750@2759|Eukaryota,37UKS@33090|Viridiplantae,3GIMC@35493|Streptophyta,4JU73@91835|fabids	35493|Streptophyta	J	Ribosomal protein S12/S23	rps12	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464	-	ko:K02950	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosom_S12_S23
k141_4097_2	686578.AFFX01000006_gene3306	1.78e-75	240.0	COG3637@1|root,COG3637@2|Bacteria,1R3Z1@1224|Proteobacteria	1224|Proteobacteria	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_2864_1	13035.Dacsa_2837	3.94e-10	65.9	COG2304@1|root,COG2834@1|root,COG2931@1|root,COG3209@1|root,COG5184@1|root,COG2304@2|Bacteria,COG2834@2|Bacteria,COG2931@2|Bacteria,COG3209@2|Bacteria,COG5184@2|Bacteria,1G1WI@1117|Cyanobacteria	1117|Cyanobacteria	Q	PFAM Bacterial pre-peptidase C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,Cadherin,Calx-beta,PPC
k141_8376_1	1120999.JONM01000009_gene321	6.63e-56	181.0	COG0175@1|root,COG0175@2|Bacteria,1MXUR@1224|Proteobacteria,2VIR0@28216|Betaproteobacteria,2KQ7F@206351|Neisseriales	206351|Neisseriales	C	Reduction of activated sulfate into sulfite	cysH	-	1.8.4.10,1.8.4.8	ko:K00390	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00176	R02021	RC00007,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	-	PAPS_reduct
k141_8376_2	1121115.AXVN01000104_gene847	3.53e-05	45.8	COG0175@1|root,COG0175@2|Bacteria,1U1VN@1239|Firmicutes,248Y9@186801|Clostridia,3Y143@572511|Blautia	186801|Clostridia	H	Phosphoadenosine phosphosulfate reductase family	cysD	-	1.8.4.10,1.8.4.8,2.7.7.4	ko:K00390,ko:K00957	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R02021,R04929	RC00007,RC02809,RC02862,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	PAPS_reduct
k141_6561_1	159749.K0S1E8	1.49e-54	204.0	COG2801@1|root,KOG0017@2759|Eukaryota,2XEGG@2836|Bacillariophyta	2836|Bacillariophyta	L	transposition, RNA-mediated	-	-	-	-	-	-	-	-	-	-	-	-	RVT_2,gag_pre-integrs,rve,zf-CCHC
k141_3455_1	159749.K0TDD2	5.93e-35	138.0	COG2801@1|root,KOG3098@1|root,KOG0017@2759|Eukaryota,KOG3098@2759|Eukaryota	2759|Eukaryota	S	G-protein coupled peptide receptor activity	-	GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0022857,GO:0051179,GO:0051234,GO:0055085	-	-	-	-	-	-	-	-	-	-	MFS_1,UNC-93
k141_2252_1	1354722.JQLS01000008_gene3799	7.98e-96	288.0	COG0116@1|root,COG0116@2|Bacteria,1MUQM@1224|Proteobacteria,2TSWI@28211|Alphaproteobacteria,46Q3V@74030|Roseovarius	28211|Alphaproteobacteria	L	N6-adenine-specific DNA methylase	rlmL	-	2.1.1.173,2.1.1.264	ko:K07444,ko:K12297	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	THUMP,UPF0020
k141_397_1	187272.Mlg_0893	7.05e-13	67.4	COG1815@1|root,COG1815@2|Bacteria,1MZ8P@1224|Proteobacteria,1S9DS@1236|Gammaproteobacteria,1WYJC@135613|Chromatiales	135613|Chromatiales	N	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body	-	-	-	ko:K02387	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod
k141_6562_2	909943.HIMB100_00004090	4.7e-58	194.0	COG3333@1|root,COG3333@2|Bacteria,1MUKR@1224|Proteobacteria,2TR4Q@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Protein conserved in bacteria	-	-	-	ko:K07793	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.80.1	-	-	TctA
k141_7743_1	246197.MXAN_0581	1.42e-22	95.1	COG0290@1|root,COG0290@2|Bacteria,1RDD2@1224|Proteobacteria,42RHA@68525|delta/epsilon subdivisions,2WNQW@28221|Deltaproteobacteria,2YVAJ@29|Myxococcales	28221|Deltaproteobacteria	J	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins	infC	GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008	-	ko:K02520	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	IF3_C,IF3_N
k141_8971_2	1122214.AQWH01000016_gene1610	2.19e-17	80.9	COG0398@1|root,COG0398@2|Bacteria,1RDZ2@1224|Proteobacteria,2U8CD@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	membrane	ydjZ	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
k141_5941_1	666509.RCA23_c10640	5.49e-19	81.6	COG3193@1|root,COG3193@2|Bacteria,1N08N@1224|Proteobacteria,2U5ES@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	protein possibly involved in utilization of glycolate and propanediol	-	-	-	-	-	-	-	-	-	-	-	-	Haem_degrading
k141_5941_2	1123237.Salmuc_05100	9.44e-75	250.0	COG2225@1|root,COG5265@1|root,COG2225@2|Bacteria,COG5265@2|Bacteria,1MVEV@1224|Proteobacteria,2TS9R@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA	glcB	-	2.3.3.9	ko:K01638	ko00620,ko00630,ko01100,ko01110,ko01120,ko01200,map00620,map00630,map01100,map01110,map01120,map01200	M00012	R00472	RC00004,RC00308,RC02747	ko00000,ko00001,ko00002,ko01000	-	-	-	Malate_synthase
k141_6563_2	13035.Dacsa_1788	5.33e-18	87.8	COG1404@1|root,COG1404@2|Bacteria,1G0DF@1117|Cyanobacteria	1117|Cyanobacteria	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	HemolysinCabind,Peptidase_S8
k141_1010_2	331869.BAL199_12091	1.43e-60	194.0	COG4221@1|root,COG4221@2|Bacteria,1MWXS@1224|Proteobacteria,2TQYY@28211|Alphaproteobacteria,4BPDX@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	S	KR domain	MA20_32450	-	-	-	-	-	-	-	-	-	-	-	adh_short
k141_5337_1	1238182.C882_3989	4.55e-25	105.0	COG4663@1|root,COG4663@2|Bacteria,1MVMD@1224|Proteobacteria,2TS4J@28211|Alphaproteobacteria,2JPP5@204441|Rhodospirillales	204441|Rhodospirillales	Q	Part of the tripartite ATP-independent periplasmic (TRAP) transport system	-	-	-	-	-	-	-	-	-	-	-	-	DctP
k141_9627_1	763034.HMPREF9446_01166	3.17e-112	345.0	COG1048@1|root,COG1048@2|Bacteria,4NDZT@976|Bacteroidetes,2FMDQ@200643|Bacteroidia,4AM3U@815|Bacteroidaceae	976|Bacteroidetes	C	Psort location Cytoplasmic, score	acnA	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
k141_399_1	1282876.BAOK01000001_gene948	1.49e-43	153.0	COG0410@1|root,COG0410@2|Bacteria,1MVVC@1224|Proteobacteria,2TSA6@28211|Alphaproteobacteria,4BQ2W@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	E	Amino acid amide ABC transporter ATP-binding protein 2, HAAT family	MA20_22615	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
k141_4720_1	522306.CAP2UW1_1124	6.44e-148	433.0	COG0446@1|root,COG0607@1|root,COG0446@2|Bacteria,COG0607@2|Bacteria,1NR3M@1224|Proteobacteria,2VJKF@28216|Betaproteobacteria	28216|Betaproteobacteria	P	FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	-	ko:K04085	ko04122,map04122	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	DrsE_2,Pyr_redox_2,Pyr_redox_dim,Rhodanese,TusA
k141_5942_1	765912.Thimo_0970	2.3e-52	176.0	COG0613@1|root,COG0613@2|Bacteria,1MWIH@1224|Proteobacteria,1RNCG@1236|Gammaproteobacteria,1WXKB@135613|Chromatiales	135613|Chromatiales	S	pfam php	-	-	3.1.3.97	ko:K07053	-	-	R00188,R11188	RC00078	ko00000,ko01000	-	-	-	PHP
k141_1011_1	472759.Nhal_2603	5.45e-81	265.0	COG0243@1|root,COG0437@1|root,COG0243@2|Bacteria,COG0437@2|Bacteria,1MU1B@1224|Proteobacteria,1SYJH@1236|Gammaproteobacteria,1WWTE@135613|Chromatiales	135613|Chromatiales	C	PFAM 4Fe-4S	-	-	-	ko:K00184,ko:K21308	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R11487	RC00168	ko00000,ko00001	5.A.3	-	-	Fer4_11,Fer4_4,Fer4_7
k141_1634_1	1380600.AUYN01000009_gene1211	4.73e-84	256.0	COG1409@1|root,COG1409@2|Bacteria,4NKP0@976|Bacteroidetes,1HY1S@117743|Flavobacteriia	976|Bacteroidetes	S	Calcineurin-like phosphoesterase	-	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	Metallophos,SASA
k141_5943_1	1392498.JQLH01000001_gene1489	2.1e-70	238.0	COG2911@1|root,COG2911@2|Bacteria,4NF7F@976|Bacteroidetes,1HWKQ@117743|Flavobacteriia,2PG8A@252356|Maribacter	976|Bacteroidetes	S	TamB, inner membrane protein subunit of TAM complex	-	-	-	-	-	-	-	-	-	-	-	-	TamB
k141_8379_1	159749.K0TBF7	2.33e-84	286.0	COG2801@1|root,KOG0017@2759|Eukaryota,2XEDA@2836|Bacillariophyta	2836|Bacillariophyta	L	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	RVT_2
k141_1012_1	504487.JCM19302_3302	2.64e-52	169.0	COG2884@1|root,COG2884@2|Bacteria,4NEP2@976|Bacteroidetes,1HY06@117743|Flavobacteriia	976|Bacteroidetes	D	atp-binding protein	ftsE	-	-	ko:K09812	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	ABC_tran
k141_9628_1	1101189.AQUO01000002_gene733	1.95e-43	149.0	COG2801@1|root,COG2801@2|Bacteria,1MVC8@1224|Proteobacteria,2TRX0@28211|Alphaproteobacteria,2PWUE@265|Paracoccus	28211|Alphaproteobacteria	L	HTH-like domain	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve
k141_9628_2	1207063.P24_18864	2.46e-54	171.0	COG2963@1|root,COG2963@2|Bacteria,1N06K@1224|Proteobacteria,2VEYA@28211|Alphaproteobacteria,2JYNY@204441|Rhodospirillales	204441|Rhodospirillales	L	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Tnp_1
k141_2869_1	1380394.JADL01000009_gene3286	1.02e-64	217.0	COG5426@1|root,COG5426@2|Bacteria,1MVWA@1224|Proteobacteria,2TQNQ@28211|Alphaproteobacteria,2JQ89@204441|Rhodospirillales	204441|Rhodospirillales	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_7746_1	314264.ROS217_17015	2.56e-05	45.1	2AEEA@1|root,31493@2|Bacteria,1PTRU@1224|Proteobacteria,2VB8R@28211|Alphaproteobacteria,46R8F@74030|Roseovarius	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_7746_2	391589.RGAI101_2101	4.02e-68	216.0	COG1469@1|root,COG1469@2|Bacteria,1MV1B@1224|Proteobacteria,2TUES@28211|Alphaproteobacteria,2P1VS@2433|Roseobacter	28211|Alphaproteobacteria	S	Converts GTP to 7,8-dihydroneopterin triphosphate	folE2	-	3.5.4.16	ko:K09007	ko00790,ko01100,map00790,map01100	M00126	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	GCHY-1
k141_7807_1	713586.KB900536_gene1835	8.97e-40	150.0	COG4796@1|root,COG4796@2|Bacteria,1QTT6@1224|Proteobacteria,1RN3Z@1236|Gammaproteobacteria,1WWYN@135613|Chromatiales	135613|Chromatiales	U	type IV pilus secretin PilQ	-	-	-	ko:K02666	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	AMIN,STN,Secretin,Secretin_N
k141_4788_1	985054.JQEZ01000003_gene1300	4.04e-46	163.0	COG3845@1|root,COG3845@2|Bacteria,1NT0H@1224|Proteobacteria,2UPJ8@28211|Alphaproteobacteria,4N9U3@97050|Ruegeria	28211|Alphaproteobacteria	S	ATPases associated with a variety of cellular activities	rbsA4	-	3.6.3.17	ko:K02056	-	M00221	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.2	-	-	ABC_tran
k141_4788_2	391616.OA238_c14520	7.09e-08	52.8	COG1172@1|root,COG1172@2|Bacteria,1MX7D@1224|Proteobacteria,2TT59@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K10440	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	BPD_transp_2
k141_4171_1	159749.K0RFD6	3.88e-27	115.0	29KWX@1|root,2RU66@2759|Eukaryota,2XCA0@2836|Bacillariophyta	2836|Bacillariophyta	-	-	-	-	-	ko:K11497	-	-	-	-	ko00000,ko03036	-	-	-	-
k141_5399_1	10228.TriadP63066	1.82e-132	380.0	COG0719@1|root,2QRGW@2759|Eukaryota,39YBY@33154|Opisthokonta,3BMZB@33208|Metazoa	33208|Metazoa	O	Uncharacterized protein family (UPF0051)	-	-	-	-	-	-	-	-	-	-	-	-	UPF0051
k141_1704_1	396588.Tgr7_0454	1.5e-104	319.0	COG1178@1|root,COG1178@2|Bacteria,1MWEV@1224|Proteobacteria,1RP55@1236|Gammaproteobacteria,1WWS0@135613|Chromatiales	135613|Chromatiales	P	inner membrane component	-	-	-	ko:K02011	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	BPD_transp_1
k141_7808_1	159749.K0S1E8	1.07e-46	172.0	COG2801@1|root,KOG0017@2759|Eukaryota,2XEGG@2836|Bacillariophyta	2836|Bacillariophyta	L	transposition, RNA-mediated	-	-	-	-	-	-	-	-	-	-	-	-	RVT_2,gag_pre-integrs,rve,zf-CCHC
k141_9038_1	313628.LNTAR_10606	1.52e-25	113.0	COG3666@1|root,COG3666@2|Bacteria	2|Bacteria	-	-	tnp15	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_6,DUF772
k141_5400_1	1229909.NSED_07870	4.4e-24	95.1	arCOG08730@1|root,arCOG08730@2157|Archaea,41SNH@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_471_1	246200.SPO0702	6.96e-113	332.0	COG4608@1|root,COG4608@2|Bacteria,1NU4K@1224|Proteobacteria,2TQTV@28211|Alphaproteobacteria,4NC03@97050|Ruegeria	28211|Alphaproteobacteria	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
k141_4173_1	493475.GARC_0239	7.55e-23	92.4	COG0319@1|root,COG0319@2|Bacteria,1MZ67@1224|Proteobacteria,1S6BS@1236|Gammaproteobacteria,467I5@72275|Alteromonadaceae	1236|Gammaproteobacteria	J	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA	ybeY	GO:0000469,GO:0000478,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0005488,GO:0006139,GO:0006355,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016072,GO:0016151,GO:0016787,GO:0016788,GO:0016892,GO:0016894,GO:0019219,GO:0019222,GO:0019538,GO:0022613,GO:0030490,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043244,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:2000112,GO:2001141	-	ko:K07042	-	-	-	-	ko00000,ko03009	-	-	-	UPF0054
k141_4173_2	1127673.GLIP_0272	4.81e-44	152.0	COG1702@1|root,COG1702@2|Bacteria,1MVDV@1224|Proteobacteria,1RP2Y@1236|Gammaproteobacteria,464W4@72275|Alteromonadaceae	1236|Gammaproteobacteria	T	COG1702 Phosphate starvation-inducible protein PhoH	ybeZ	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K06217	-	-	-	-	ko00000	-	-	-	PhoH
k141_4790_1	1547437.LL06_26180	9.63e-96	283.0	COG3335@1|root,COG3335@2|Bacteria,1P76X@1224|Proteobacteria,2VBH8@28211|Alphaproteobacteria,43P72@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3
k141_2935_1	582899.Hden_0695	3.84e-15	74.7	2AKRU@1|root,31BIQ@2|Bacteria,1Q7DM@1224|Proteobacteria,2UEKS@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_472_1	396588.Tgr7_1274	5.62e-80	245.0	COG0378@1|root,COG0378@2|Bacteria,1MVBD@1224|Proteobacteria,1RN9Y@1236|Gammaproteobacteria,1WWGI@135613|Chromatiales	135613|Chromatiales	KO	TIGRFAM Hydrogenase accessory protein HypB	-	-	-	ko:K04652	-	-	-	-	ko00000,ko03110	-	-	-	cobW
k141_6636_1	1305735.JAFT01000005_gene1328	5.54e-81	248.0	COG2857@1|root,COG2857@2|Bacteria,1QFU2@1224|Proteobacteria,2TUHX@28211|Alphaproteobacteria,2PD5H@252301|Oceanicola	28211|Alphaproteobacteria	C	Cytochrome C1 family	petC	-	-	ko:K00413	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002	-	-	-	Cytochrom_C1
k141_6636_2	1300350.DSW25_02270	6.2e-07	50.4	COG1290@1|root,COG1290@2|Bacteria,1MV97@1224|Proteobacteria,2TSZ3@28211|Alphaproteobacteria,3ZVR0@60136|Sulfitobacter	28211|Alphaproteobacteria	C	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis	petB	-	-	ko:K00410,ko:K00412	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002,ko03029	-	-	-	Cytochrom_B_C,Cytochrom_C1,Cytochrome_B
k141_9040_2	391937.NA2_00250	2.25e-60	192.0	COG2151@1|root,COG2151@2|Bacteria,1RF3S@1224|Proteobacteria,2TRQW@28211|Alphaproteobacteria,43K72@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	Iron-sulfur cluster assembly protein	paaJ	-	-	ko:K02612	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001	-	-	-	FeS_assembly_P
k141_8451_1	1121875.KB907546_gene2199	1.05e-166	480.0	COG3653@1|root,COG3653@2|Bacteria,4NHDD@976|Bacteroidetes,1I2RR@117743|Flavobacteriia	976|Bacteroidetes	Q	PFAM D-aminoacylase, C-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,Amidohydro_3
k141_2936_1	243924.LT42_16005	4.58e-31	114.0	COG0723@1|root,COG0723@2|Bacteria,1RAA2@1224|Proteobacteria,1RP9H@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis	petA	-	1.10.2.2	ko:K00411	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002,ko01000	-	-	-	Rieske,UCR_Fe-S_N
k141_2936_2	713587.THITH_14555	1.84e-76	241.0	COG1290@1|root,COG1290@2|Bacteria,1MV97@1224|Proteobacteria,1RNCP@1236|Gammaproteobacteria,1WWQP@135613|Chromatiales	135613|Chromatiales	C	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis	petB	-	-	ko:K00412	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002,ko03029	-	-	-	Cytochrom_B_C,Cytochrome_B
k141_473_1	204773.HEAR3342	3.64e-125	383.0	COG0243@1|root,COG0243@2|Bacteria,1P01N@1224|Proteobacteria,2W94M@28216|Betaproteobacteria,47825@75682|Oxalobacteraceae	28216|Betaproteobacteria	C	Molybdopterin oxidoreductase Fe4S4 domain	-	-	1.8.5.6	ko:K21307	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R11487	RC00168	ko00000,ko00001,ko01000	-	-	-	Molybdopterin,Molydop_binding
k141_6637_1	1229909.NSED_01340	6.97e-36	126.0	COG5424@1|root,arCOG06031@2157|Archaea,41SJK@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Iron-containing redox enzyme	-	-	1.3.3.11	ko:K06137	-	-	-	-	ko00000,ko01000	-	-	-	-
k141_6637_2	1229909.NSED_01335	4.99e-25	100.0	COG0142@1|root,arCOG01727@2157|Archaea,41SC6@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Belongs to the FPP GGPP synthase family	-	-	2.5.1.90	ko:K02523	ko00900,ko01110,map00900,map01110	-	R09248	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	-	polyprenyl_synt
k141_7932_2	305900.GV64_00725	2.1e-43	149.0	COG1173@1|root,COG1173@2|Bacteria,1MU26@1224|Proteobacteria,1RND6@1236|Gammaproteobacteria,1XH9S@135619|Oceanospirillales	135619|Oceanospirillales	EP	N-terminal TM domain of oligopeptide transport permease C	-	-	-	ko:K02034,ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1,OppC_N
k141_3063_1	159749.K0R914	3.16e-41	154.0	COG2801@1|root,KOG0017@2759|Eukaryota,2XEDA@2836|Bacillariophyta	159749.K0R914|-	L	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_9168_1	1530186.JQEY01000010_gene2849	1.55e-110	342.0	COG0542@1|root,COG0542@2|Bacteria,1MURH@1224|Proteobacteria,2TRKI@28211|Alphaproteobacteria	28211|Alphaproteobacteria	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
k141_6756_1	592015.HMPREF1705_02026	2.97e-43	149.0	COG0778@1|root,COG0778@2|Bacteria,3TCD8@508458|Synergistetes	508458|Synergistetes	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
k141_1206_2	981085.XP_010103454.1	6.86e-56	193.0	COG1034@1|root,KOG2282@2759|Eukaryota,37RAU@33090|Viridiplantae,3GFDF@35493|Streptophyta,4JJZI@91835|fabids	35493|Streptophyta	C	Belongs to the complex I 75 kDa subunit family	-	-	1.6.5.3,1.6.99.3	ko:K03934	ko00190,ko01100,ko04714,ko04723,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map04714,map04723,map04932,map05010,map05012,map05016	M00143	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1.6	-	-	Fer2_4,Molybdopterin,NADH-G_4Fe-4S_3,NADH_dhqG_C
k141_8568_1	1380394.JADL01000009_gene3336	4.88e-65	207.0	COG0625@1|root,COG0625@2|Bacteria,1RC4Y@1224|Proteobacteria,2U6JK@28211|Alphaproteobacteria,2JTHK@204441|Rhodospirillales	204441|Rhodospirillales	O	Glutathione S-transferase, N-terminal domain	-	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C,GST_C_2,GST_N,GST_N_3
k141_3641_1	104355.XP_007871309.1	1.03e-13	64.7	2E1I0@1|root,2S8UZ@2759|Eukaryota,3A9DK@33154|Opisthokonta,3Q6KM@4751|Fungi,3V5DS@5204|Basidiomycota	4751|Fungi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_3064_1	391595.RLO149_c007340	7.7e-62	204.0	COG2376@1|root,COG2376@2|Bacteria,1MVSR@1224|Proteobacteria,2TTK3@28211|Alphaproteobacteria,2P15S@2433|Roseobacter	28211|Alphaproteobacteria	G	Dak2	dhaK	-	2.7.1.28,2.7.1.29,4.6.1.15	ko:K00863	ko00051,ko00561,ko00680,ko01100,ko01120,ko01200,ko04622,map00051,map00561,map00680,map01100,map01120,map01200,map04622	M00344	R01011,R01059	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Dak1,Dak2
k141_3064_2	1123229.AUBC01000003_gene2170	2.23e-19	86.3	COG3842@1|root,COG3842@2|Bacteria,1QYZ3@1224|Proteobacteria,2TT89@28211|Alphaproteobacteria,3JUMF@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	TOBE domain	smoK	-	-	ko:K10112	ko02010,map02010	M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1	-	-	ABC_tran,TOBE_2
k141_9810_1	1178825.ALIH01000020_gene2745	1.16e-06	55.1	COG4932@1|root,COG4932@2|Bacteria,4NKIK@976|Bacteroidetes,1IK2U@117743|Flavobacteriia	976|Bacteroidetes	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_5535_1	292415.Tbd_1646	6.43e-47	159.0	COG1150@1|root,COG1150@2|Bacteria,1RHH3@1224|Proteobacteria,2W0PC@28216|Betaproteobacteria,1KSVN@119069|Hydrogenophilales	119069|Hydrogenophilales	C	4Fe-4S dicluster domain	-	-	-	ko:K16887	-	-	-	-	ko00000	-	-	-	Fer4_17
k141_6758_1	633131.TR2A62_1834	1.03e-34	129.0	COG0044@1|root,COG0044@2|Bacteria,1MW10@1224|Proteobacteria,2TSQH@28211|Alphaproteobacteria	28211|Alphaproteobacteria	F	COG0044 Dihydroorotase and related cyclic amidohydrolases	dht	-	3.5.2.2	ko:K01464	ko00240,ko00410,ko00770,ko00983,ko01100,map00240,map00410,map00770,map00983,map01100	M00046	R02269,R03055,R08227	RC00632,RC00680	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Amidohydro_1
k141_6758_2	391593.RCCS2_08564	2.19e-60	196.0	COG0624@1|root,COG0624@2|Bacteria,1MVUX@1224|Proteobacteria,2TR5X@28211|Alphaproteobacteria,2P1EJ@2433|Roseobacter	28211|Alphaproteobacteria	E	COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases	amaB	GO:0003674,GO:0005488,GO:0005515,GO:0042802	3.5.1.6,3.5.1.87	ko:K06016	ko00240,ko01100,map00240,map01100	M00046	R00905,R04666	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
k141_2445_1	517418.Ctha_0006	3.26e-17	84.7	COG0188@1|root,COG0188@2|Bacteria,1FDDQ@1090|Chlorobi	1090|Chlorobi	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
k141_5536_1	1380394.JADL01000005_gene5393	1.22e-82	260.0	COG1008@1|root,COG1008@2|Bacteria,1MV7V@1224|Proteobacteria,2TSNK@28211|Alphaproteobacteria,2JPNK@204441|Rhodospirillales	204441|Rhodospirillales	C	COG1008 NADH ubiquinone oxidoreductase subunit 4 (chain M)	nuoM	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q5_N,Proton_antipo_M
k141_1833_1	204773.HEAR1583	1.53e-30	114.0	COG4454@1|root,COG4454@2|Bacteria,1R91G@1224|Proteobacteria,2VSDP@28216|Betaproteobacteria,474YT@75682|Oxalobacteraceae	28216|Betaproteobacteria	P	Copper binding proteins, plastocyanin/azurin family	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind,Cupredoxin_1,CusF_Ec
k141_1833_2	1265502.KB905930_gene1422	1.42e-20	89.7	COG2132@1|root,COG2132@2|Bacteria,1MU0J@1224|Proteobacteria,2VM67@28216|Betaproteobacteria,4A9NI@80864|Comamonadaceae	28216|Betaproteobacteria	Q	PFAM multicopper oxidase type	-	-	1.16.3.3	ko:K22348	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase_2,Cu-oxidase_3
k141_4910_1	1131812.JQMS01000001_gene914	1.27e-68	216.0	COG0224@1|root,COG0224@2|Bacteria,4NECM@976|Bacteroidetes,1HX6V@117743|Flavobacteriia,2NTZB@237|Flavobacterium	976|Bacteroidetes	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	-	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
k141_8570_1	330214.NIDE3074	6.58e-77	243.0	COG0541@1|root,COG0541@2|Bacteria,3J0DT@40117|Nitrospirae	40117|Nitrospirae	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY	ffh	-	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
k141_4293_1	1038866.KB902802_gene7125	2.13e-69	218.0	COG0410@1|root,COG0410@2|Bacteria,1MVVC@1224|Proteobacteria,2TR61@28211|Alphaproteobacteria,3JUH1@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	AAA domain, putative AbiEii toxin, Type IV TA system	MA20_19430	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,DLIC
k141_9172_1	394221.Mmar10_0175	7.03e-66	207.0	COG3316@1|root,COG3316@2|Bacteria,1P9SM@1224|Proteobacteria,2TV17@28211|Alphaproteobacteria,43XZD@69657|Hyphomonadaceae	28211|Alphaproteobacteria	L	COG3316 Transposase and inactivated derivatives	-	-	-	ko:K07498	-	-	-	-	ko00000	-	-	-	DDE_Tnp_IS240
k141_6144_1	1229909.NSED_08695	1.84e-43	145.0	COG1303@1|root,arCOG01857@2157|Archaea,41SIR@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs	-	-	2.1.1.206	ko:K07254	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Trm56
k141_6144_2	1229909.NSED_08700	1.95e-62	194.0	COG1675@1|root,arCOG04270@2157|Archaea,41SJ8@651137|Thaumarchaeota	651137|Thaumarchaeota	K	Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes. Seems to translocate with the RNA polymerase following initiation and acts by binding to the non template strand of the transcription bubble in elongation complexes	tfe	-	-	ko:K03136	ko03022,ko05169,ko05203,map03022,map05169,map05203	-	-	-	ko00000,ko00001,ko03021	-	-	-	TFIIE_alpha
k141_4911_1	411684.HPDFL43_02864	8.35e-39	149.0	COG2304@1|root,COG2911@1|root,COG2931@1|root,COG2304@2|Bacteria,COG2911@2|Bacteria,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,2TRVY@28211|Alphaproteobacteria,43I5T@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	Q	COG2931 RTX toxins and related Ca2 -binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	An_peroxidase,Cadherin,DUF4214,HCBP_related,HemolysinCabind,Metallophos
k141_6760_1	394.NGR_c24980	2.73e-98	295.0	COG3335@1|root,COG3335@2|Bacteria,1MW7X@1224|Proteobacteria,2TTH8@28211|Alphaproteobacteria,4BDG3@82115|Rhizobiaceae	28211|Alphaproteobacteria	L	leucine-zipper of insertion element IS481	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,HTH_23,HTH_29,HTH_32
k141_8571_1	384765.SIAM614_22787	1.78e-34	130.0	COG1894@1|root,COG1894@2|Bacteria,1MV8F@1224|Proteobacteria,2TR1V@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Dehydrogenase	-	-	1.12.1.2,1.6.5.3	ko:K00335,ko:K18005	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx,Complex1_51K,NADH_4Fe-4S,SLBB
k141_8571_2	384765.SIAM614_22782	3.3e-41	142.0	COG3383@1|root,COG3383@2|Bacteria,1MXTC@1224|Proteobacteria,2U6Y9@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	4Fe-4S single cluster domain	-	-	1.12.1.2	ko:K18006	-	-	-	-	ko00000,ko01000	-	-	-	Fer2_4,Fer4_15,NADH-G_4Fe-4S_3
k141_3645_2	1297570.MESS4_260012	2.14e-16	79.3	COG0263@1|root,COG0263@2|Bacteria,1MUBG@1224|Proteobacteria,2TRKB@28211|Alphaproteobacteria,43IP6@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	E	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate	proB	GO:0003674,GO:0003824,GO:0004349,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0018130,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.2.11	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	M00015	R00239	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,PUA
k141_4294_1	391626.OAN307_c03800	2.99e-137	397.0	COG2826@1|root,COG2826@2|Bacteria,1PP49@1224|Proteobacteria,2TRVA@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	COG2826 Transposase and inactivated derivatives, IS30 family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_38,rve
k141_3646_1	1449065.JMLL01000013_gene2882	1.32e-72	231.0	COG4992@1|root,COG4992@2|Bacteria,1MV3C@1224|Proteobacteria,2TSGT@28211|Alphaproteobacteria,43H9S@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	E	acetylornithine aminotransferase	rocD	GO:0003674,GO:0005488,GO:0005515,GO:0008144,GO:0019842,GO:0030170,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363	2.6.1.11,2.6.1.13,2.6.1.17	ko:K00819,ko:K00821	ko00220,ko00300,ko00330,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map00330,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R00667,R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
k141_6145_1	1158756.AQXQ01000008_gene2371	2.59e-55	183.0	COG2081@1|root,COG2081@2|Bacteria,1MUGC@1224|Proteobacteria,1RNCW@1236|Gammaproteobacteria,1WXWG@135613|Chromatiales	135613|Chromatiales	S	fumarate reductase succinate dehydrogenase flavoprotein domain protein	-	-	-	ko:K07007	-	-	-	-	ko00000	-	-	-	HI0933_like
k141_6145_2	1485544.JQKP01000005_gene370	1.49e-36	127.0	COG3012@1|root,COG3012@2|Bacteria,1MZZK@1224|Proteobacteria,2VTZE@28216|Betaproteobacteria,44VZG@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Belongs to the UPF0225 family	ychJ	-	-	ko:K09858	-	-	-	-	ko00000	-	-	-	SEC-C
k141_1834_1	159749.E7BWP2	4.32e-08	50.4	COG0254@1|root,2S1BJ@2759|Eukaryota	2759|Eukaryota	J	rRNA binding	rpl31	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009526,GO:0009532,GO:0009536,GO:0009570,GO:0009941,GO:0031967,GO:0031975,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464	-	ko:K02909	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31
k141_596_1	1121933.AUHH01000009_gene842	1.66e-67	220.0	COG0277@1|root,COG0277@2|Bacteria,2GK5U@201174|Actinobacteria,4DPV2@85009|Propionibacteriales	201174|Actinobacteria	C	PFAM FAD linked oxidase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	BBE,FAD_binding_4
k141_6146_1	314264.ROS217_18497	2.41e-111	326.0	COG1351@1|root,COG1351@2|Bacteria,1MWY8@1224|Proteobacteria,2TTER@28211|Alphaproteobacteria,46PEX@74030|Roseovarius	28211|Alphaproteobacteria	H	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant	thyX	-	2.1.1.148	ko:K03465	ko00240,ko00670,ko01100,map00240,map00670,map01100	-	R06613	RC00022,RC00332	ko00000,ko00001,ko01000	-	-	-	Thy1
k141_9175_1	10228.TriadP63021	3.77e-44	156.0	COG0072@1|root,KOG2472@2759|Eukaryota,3A7RT@33154|Opisthokonta,3BXEE@33208|Metazoa	33208|Metazoa	J	phenylalanine--tRNA ligase beta	-	-	-	-	-	-	-	-	-	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
k141_9815_1	1121930.AQXG01000001_gene1459	1.16e-46	171.0	COG0708@1|root,COG2373@1|root,COG2911@1|root,COG2931@1|root,COG3210@1|root,COG5306@1|root,COG0708@2|Bacteria,COG2373@2|Bacteria,COG2911@2|Bacteria,COG2931@2|Bacteria,COG3210@2|Bacteria,COG5306@2|Bacteria,4NXBA@976|Bacteroidetes,1IZ5A@117747|Sphingobacteriia	976|Bacteroidetes	Q	alpha-L-arabinofuranosidase	-	-	-	-	-	-	-	-	-	-	-	-	Invasin_D3
k141_4913_1	998674.ATTE01000001_gene279	7.85e-116	347.0	COG5598@1|root,COG5598@2|Bacteria,1MWJN@1224|Proteobacteria,1S1SA@1236|Gammaproteobacteria	1236|Gammaproteobacteria	H	Trimethylamine methyltransferase (MTTB)	-	-	-	-	-	-	-	-	-	-	-	-	MTTB
k141_3070_1	1123399.AQVE01000013_gene307	1.85e-94	289.0	COG0719@1|root,COG0719@2|Bacteria,1MVKY@1224|Proteobacteria,1RQ65@1236|Gammaproteobacteria,45ZMX@72273|Thiotrichales	72273|Thiotrichales	O	FeS assembly protein SufB	sufB	-	-	ko:K09014	-	-	-	-	ko00000	-	-	-	UPF0051
k141_4297_1	167539.Pro_0271	2.78e-06	55.1	COG1109@1|root,COG1109@2|Bacteria,1G0RP@1117|Cyanobacteria,1MKJW@1212|Prochloraceae	1117|Cyanobacteria	G	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate	glmM	-	5.4.2.10	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	-	R02060	RC00408	ko00000,ko00001,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
k141_7372_1	998674.ATTE01000001_gene3154	9.16e-80	248.0	COG0665@1|root,COG0665@2|Bacteria,1MVM6@1224|Proteobacteria,1RRHH@1236|Gammaproteobacteria,46084@72273|Thiotrichales	72273|Thiotrichales	E	FAD dependent oxidoreductase	-	-	1.5.3.1	ko:K00303	ko00260,ko01100,map00260,map01100	-	R00610	RC00060,RC00557	ko00000,ko00001,ko01000	-	-	-	DAO
k141_2450_1	443144.GM21_1631	3.92e-59	203.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,42M51@68525|delta/epsilon subdivisions,2WIPP@28221|Deltaproteobacteria,43TCZ@69541|Desulfuromonadales	28221|Deltaproteobacteria	NU	General secretory system II, protein E domain protein	pilB	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE,T2SSE_N,cNMP_binding
k141_1837_1	391593.RCCS2_14664	5.52e-85	269.0	COG4770@1|root,COG4770@2|Bacteria,1P6RE@1224|Proteobacteria,2TRC2@28211|Alphaproteobacteria,2P25M@2433|Roseobacter	28211|Alphaproteobacteria	I	COG4770 Acetyl propionyl-CoA carboxylase, alpha subunit	pccA	-	6.4.1.3	ko:K01965	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	M00373,M00741	R01859	RC00097,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2
k141_6764_1	118168.MC7420_6572	9.75e-06	43.9	2EI42@1|root,33BVG@2|Bacteria,1GAFT@1117|Cyanobacteria,1HDJ7@1150|Oscillatoriales	1117|Cyanobacteria	S	Manganese-binding polypeptide with L-arginine metabolizing enzyme activity. Component of the core of photosystem II	psbY	-	-	ko:K02723	ko00195,ko01100,map00195,map01100	-	-	-	ko00000,ko00001,ko00194	-	-	-	PsbY
k141_1913_1	67593.Physo108886	5.09e-27	114.0	COG2801@1|root,KOG0017@2759|Eukaryota,3QHRW@4776|Peronosporales	67593.Physo108886|-	L	transposition, RNA-mediated	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_6227_1	7739.XP_002590018.1	9.2e-15	73.2	2D0S2@1|root,2SF6P@2759|Eukaryota	2759|Eukaryota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_9311_1	391595.RLO149_c017560	4.44e-130	375.0	COG2826@1|root,COG2826@2|Bacteria,1PP49@1224|Proteobacteria,2TRVA@28211|Alphaproteobacteria,2P2YR@2433|Roseobacter	28211|Alphaproteobacteria	L	COG2826 Transposase and inactivated derivatives, IS30 family	-	-	-	ko:K07482	-	-	-	-	ko00000	-	-	-	HTH_38,rve
k141_63_1	35128.Thapsdraft1267	0.0	931.0	COG0085@1|root,KOG0214@2759|Eukaryota,2XEM3@2836|Bacillariophyta	2836|Bacillariophyta	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	-	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009536,GO:0030880,GO:0032991,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0061695,GO:1902494,GO:1990234	-	-	-	-	-	-	-	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
k141_5615_1	765910.MARPU_10910	8.46e-127	367.0	COG2221@1|root,COG2221@2|Bacteria,1MVZQ@1224|Proteobacteria,1RQXZ@1236|Gammaproteobacteria,1WWM7@135613|Chromatiales	135613|Chromatiales	C	reductase, dissimilatory-type beta subunit	dsrB	-	1.8.99.5	ko:K11181	ko00633,ko00920,ko01100,ko01120,map00633,map00920,map01100,map01120	M00596	R00295,R00861,R08035	RC00065,RC01760	ko00000,ko00001,ko00002,ko01000	-	-	-	NIR_SIR,NIR_SIR_ferr
k141_677_1	35128.Thapsdraft1396	2.67e-53	169.0	COG0335@1|root,KOG1698@2759|Eukaryota,2XFXY@2836|Bacillariophyta	2836|Bacillariophyta	J	Ribosomal protein L19	-	GO:0000313,GO:0000315,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005761,GO:0005762,GO:0005840,GO:0009507,GO:0009536,GO:0015934,GO:0031974,GO:0032991,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044391,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0070013,GO:0098798,GO:1990904	-	-	-	-	-	-	-	-	-	-	Ribosomal_L19
k141_4992_1	1390370.O203_17980	3.49e-63	216.0	COG1752@1|root,COG4775@1|root,COG1752@2|Bacteria,COG4775@2|Bacteria,1MUM9@1224|Proteobacteria,1RRSK@1236|Gammaproteobacteria,1YEC5@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	M	Patatin-like phospholipase	plpD	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Bac_surface_Ag,POTRA,Patatin
k141_8060_1	1282876.BAOK01000001_gene1503	1.62e-94	304.0	COG0587@1|root,COG0587@2|Bacteria,1MUE4@1224|Proteobacteria,2TRUB@28211|Alphaproteobacteria,4BRG8@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	L	DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase	dnaE2	GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496	2.7.7.7	ko:K02337,ko:K14162	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
k141_9313_1	1235457.C404_04035	2.03e-66	217.0	COG0364@1|root,COG0364@2|Bacteria,1MUN0@1224|Proteobacteria,2VHS1@28216|Betaproteobacteria,1K0N4@119060|Burkholderiaceae	28216|Betaproteobacteria	G	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone	zwf	-	1.1.1.363,1.1.1.49	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	M00004,M00006,M00008	R00835,R02736,R10907	RC00001,RC00066	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	G6PD_C,G6PD_N
k141_6840_2	1335757.SPICUR_06140	9.3e-37	134.0	COG0604@1|root,COG0604@2|Bacteria,1MX8A@1224|Proteobacteria,1RQ9K@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	alcohol dehydrogenase	-	-	1.1.1.1,1.6.5.5	ko:K00001,ko:K00344	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
k141_6840_3	187272.Mlg_2059	5.94e-34	125.0	COG0604@1|root,COG0604@2|Bacteria,1MX8A@1224|Proteobacteria,1RQ9K@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	alcohol dehydrogenase	-	-	1.1.1.1,1.6.5.5	ko:K00001,ko:K00344	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
k141_1916_1	880072.Desac_2373	2.98e-07	53.1	COG3009@1|root,COG3009@2|Bacteria,1N8BW@1224|Proteobacteria,42UW2@68525|delta/epsilon subdivisions,2WQFD@28221|Deltaproteobacteria,2MS52@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	ABC-type transport auxiliary lipoprotein component	-	-	-	ko:K09857	-	-	-	-	ko00000	-	-	-	ABC_trans_aux
k141_678_1	1137799.GZ78_22295	6.58e-23	94.7	COG0356@1|root,COG0356@2|Bacteria,1MV87@1224|Proteobacteria,1RPHK@1236|Gammaproteobacteria,1XH68@135619|Oceanospirillales	135619|Oceanospirillales	C	it plays a direct role in the translocation of protons across the membrane	atpB	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
k141_678_2	187272.Mlg_2874	5.23e-31	111.0	COG0636@1|root,32S3K@2|Bacteria,1N1NA@1224|Proteobacteria,1S9MD@1236|Gammaproteobacteria,1WYXA@135613|Chromatiales	135613|Chromatiales	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpE	-	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
k141_6841_1	1218075.BAYA01000069_gene7118	6.99e-07	55.1	COG0517@1|root,COG0517@2|Bacteria,1MXI6@1224|Proteobacteria,2VJ2W@28216|Betaproteobacteria,1K2WR@119060|Burkholderiaceae	28216|Betaproteobacteria	S	transposase	-	-	-	-	-	-	-	-	-	-	-	-	Y2_Tnp,Zn_Tnp_IS91
k141_679_1	411477.PARMER_01283	8.99e-62	211.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,4NETS@976|Bacteroidetes,2FRBH@200643|Bacteroidia,22ZE0@171551|Porphyromonadaceae	976|Bacteroidetes	EU	Dipeptidyl peptidase IV (DPP IV) N-terminal region	-	-	3.4.14.5	ko:K01278	ko04974,map04974	-	-	-	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	-	-	-	DPPIV_N,Peptidase_S9
k141_1917_1	402881.Plav_2256	2.65e-77	235.0	COG0193@1|root,COG0193@2|Bacteria,1MX1P@1224|Proteobacteria,2TT6Q@28211|Alphaproteobacteria,1JNT3@119043|Rhodobiaceae	28211|Alphaproteobacteria	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
k141_8062_1	1123393.KB891316_gene1080	3.67e-44	159.0	COG1018@1|root,COG1018@2|Bacteria,1REP4@1224|Proteobacteria,2VPWB@28216|Betaproteobacteria,1KSZT@119069|Hydrogenophilales	119069|Hydrogenophilales	C	2Fe-2S iron-sulfur cluster binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer2
k141_1299_1	436308.Nmar_0549	3.35e-63	201.0	COG1685@1|root,arCOG01025@2157|Archaea,41SGZ@651137|Thaumarchaeota	651137|Thaumarchaeota	E	GHMP kinases N terminal domain	aroK	-	2.7.1.71	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
k141_1299_2	436308.Nmar_0550	5.19e-21	89.0	COG0169@1|root,arCOG01033@2157|Archaea,41S6G@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	aroE	-	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	-	Shikimate_DH,Shikimate_dh_N
k141_7521_1	2340.JV46_14900	1.34e-78	260.0	COG0587@1|root,COG0587@2|Bacteria,1MUIF@1224|Proteobacteria,1RP0K@1236|Gammaproteobacteria,1J4NP@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	L	DNA polymerase III, alpha subunit	dnaE	GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032991,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044776,GO:0046483,GO:0061695,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
k141_1401_1	991905.SL003B_1905	5.18e-14	75.1	COG0471@1|root,COG0569@1|root,COG0471@2|Bacteria,COG0569@2|Bacteria,1MU0K@1224|Proteobacteria,2TSFS@28211|Alphaproteobacteria,4BRKT@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	P	Citrate transporter	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS,TrkA_C
k141_8766_1	684719.HIMB114_00007080	4.62e-05	45.8	COG0305@1|root,COG0305@2|Bacteria,1MUG9@1224|Proteobacteria,2TSF9@28211|Alphaproteobacteria,4BPP7@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	L	it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins	dnaB	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
k141_8152_1	3885.XP_007152280.1	5.83e-52	172.0	COG0097@1|root,KOG3254@2759|Eukaryota,37NEG@33090|Viridiplantae,3GFDU@35493|Streptophyta,4JESA@91835|fabids	35493|Streptophyta	J	Belongs to the universal ribosomal protein uL6 family	-	GO:0000003,GO:0003006,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0007275,GO:0008150,GO:0009507,GO:0009526,GO:0009532,GO:0009536,GO:0009570,GO:0009719,GO:0009725,GO:0009735,GO:0009790,GO:0009791,GO:0009793,GO:0009941,GO:0010033,GO:0010154,GO:0016020,GO:0022414,GO:0031967,GO:0031975,GO:0032501,GO:0032502,GO:0042221,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0048316,GO:0048608,GO:0048731,GO:0048856,GO:0050896,GO:0061458,GO:0097159,GO:1901363	-	ko:K02933	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L6
k141_8152_2	159749.E7BWN3	1.69e-70	214.0	COG5560@1|root,KOG1870@2759|Eukaryota	2759|Eukaryota	O	ubiquitinyl hydrolase activity	rpl18	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005730,GO:0005737,GO:0008097,GO:0009507,GO:0009526,GO:0009532,GO:0009536,GO:0009570,GO:0009941,GO:0019843,GO:0031967,GO:0031974,GO:0031975,GO:0031981,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044422,GO:0044424,GO:0044428,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0070013,GO:0097159,GO:1901363	-	ko:K02881	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L18p
k141_3245_1	935863.AWZR01000003_gene2795	7.39e-117	345.0	COG1960@1|root,COG1960@2|Bacteria,1MUK0@1224|Proteobacteria,1RNBX@1236|Gammaproteobacteria,1X45S@135614|Xanthomonadales	135614|Xanthomonadales	I	Acyl-CoA dehydrogenase	gcdH	-	1.3.8.6	ko:K00252	ko00071,ko00310,ko00362,ko00380,ko01100,ko01120,ko01130,map00071,map00310,map00362,map00380,map01100,map01120,map01130	M00032	R02487,R02488,R10074	RC00052,RC00156	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
k141_2027_1	436308.Nmar_1794	3.14e-103	327.0	COG1933@1|root,arCOG04447@2157|Archaea,41SYW@651137|Thaumarchaeota	651137|Thaumarchaeota	L	Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase	polC	-	2.7.7.7	ko:K02322	ko00230,ko00240,ko01100,ko03030,map00230,map00240,map01100,map03030	M00264	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032	-	-	-	PolC_DP2
k141_9423_1	742817.HMPREF9449_01594	7.05e-37	139.0	COG1228@1|root,COG1228@2|Bacteria,4NFI3@976|Bacteroidetes,2FR1W@200643|Bacteroidia,22ZT6@171551|Porphyromonadaceae	976|Bacteroidetes	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
k141_1402_2	7668.SPU_010256-tr	5.36e-33	130.0	KOG1075@1|root,KOG1075@2759|Eukaryota	7668.SPU_010256-tr|-	E	Ribonuclease H protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_5106_1	1229909.NSED_01530	3.64e-106	316.0	COG0148@1|root,arCOG01169@2157|Archaea,41SE9@651137|Thaumarchaeota	651137|Thaumarchaeota	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
k141_8153_1	504472.Slin_5085	2.34e-116	354.0	COG0376@1|root,COG0376@2|Bacteria,4NG30@976|Bacteroidetes,47KR2@768503|Cytophagia	976|Bacteroidetes	P	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity	katG	-	1.11.1.21	ko:K03782	ko00360,ko00380,ko00940,ko00983,ko01100,ko01110,map00360,map00380,map00940,map00983,map01100,map01110	-	R00602,R00698,R02596,R02670,R03919,R04007,R07443,R11906	RC00034,RC00213,RC00767,RC02141	ko00000,ko00001,ko01000	-	-	-	peroxidase
k141_9424_1	488538.SAR116_1075	2.5e-70	235.0	COG1048@1|root,COG1048@2|Bacteria,1MU9T@1224|Proteobacteria,2TT3T@28211|Alphaproteobacteria,4BPGQ@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	C	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate	acnA	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0003994,GO:0005488,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019541,GO:0019679,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0045333,GO:0046459,GO:0047456,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0072350,GO:0097159,GO:1901363	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
k141_3864_2	159749.E7BWM8	8.94e-73	219.0	COG0093@1|root,KOG0901@2759|Eukaryota	2759|Eukaryota	J	large ribosomal subunit rRNA binding	rpl14	GO:0000313,GO:0000315,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005761,GO:0005762,GO:0005829,GO:0005840,GO:0008150,GO:0009507,GO:0009532,GO:0009534,GO:0009536,GO:0009547,GO:0009570,GO:0009579,GO:0009719,GO:0009725,GO:0009735,GO:0010033,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0031974,GO:0031976,GO:0031984,GO:0032991,GO:0042221,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043253,GO:0044391,GO:0044422,GO:0044424,GO:0044429,GO:0044434,GO:0044435,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0070013,GO:0070180,GO:0097159,GO:0098798,GO:1901363,GO:1990904	-	ko:K02874	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L14,Ribosomal_L16
k141_3864_3	159749.E7BWM7	2.3e-42	139.0	COG0186@1|root,KOG1740@2759|Eukaryota	2759|Eukaryota	J	rRNA binding	rps17	GO:0000313,GO:0000314,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005761,GO:0005763,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009507,GO:0009536,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0031974,GO:0032543,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070013,GO:0071704,GO:0098798,GO:0140053,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02961	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S17
k141_3246_1	760117.JN27_11630	6.85e-61	202.0	COG4630@1|root,COG4630@2|Bacteria,1MWI1@1224|Proteobacteria,2VI0J@28216|Betaproteobacteria,472BH@75682|Oxalobacteraceae	28216|Betaproteobacteria	F	CO dehydrogenase flavoprotein C-terminal domain	xdhA	-	1.17.1.4	ko:K13481	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103	RC00143	ko00000,ko00001,ko00002,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5,Fer2,Fer2_2
k141_6340_1	349521.HCH_02536	4.87e-51	174.0	COG0475@1|root,COG0475@2|Bacteria,1QTSD@1224|Proteobacteria,1T1FK@1236|Gammaproteobacteria,1XHU6@135619|Oceanospirillales	135619|Oceanospirillales	P	Sodium/hydrogen exchanger family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
k141_7524_2	1120949.KB903299_gene6047	1.6e-19	87.0	COG1136@1|root,COG1136@2|Bacteria,2IBG3@201174|Actinobacteria,4DHT0@85008|Micromonosporales	201174|Actinobacteria	V	ATPases associated with a variety of cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
k141_4492_1	159749.E7BWF1	1.91e-19	78.6	2EGUI@1|root,2SFCU@2759|Eukaryota	2759|Eukaryota	U	One of the components of the core complex of photosystem II (PSII). PSII is a light-driven water plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation. It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation. This subunit is found at the monomer-monomer interface and is required for correct PSII assembly and or dimerization	psbL	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009534,GO:0009535,GO:0009536,GO:0009579,GO:0016020,GO:0031976,GO:0031984,GO:0034357,GO:0042651,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044436,GO:0044444,GO:0044446,GO:0044464,GO:0055035	-	ko:K02713	ko00195,ko01100,map00195,map01100	-	-	-	ko00000,ko00001,ko00194	-	-	-	PsbL
k141_4492_2	2880.D1J7D4	9.45e-22	84.7	2E87T@1|root,2SEUE@2759|Eukaryota	2759|Eukaryota	A	photosynthetic electron transport chain	psbF	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009534,GO:0009535,GO:0009536,GO:0009579,GO:0016020,GO:0031976,GO:0031984,GO:0034357,GO:0042651,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044436,GO:0044444,GO:0044446,GO:0044464,GO:0055035	-	ko:K02708	ko00195,ko01100,map00195,map01100	M00161	-	-	ko00000,ko00001,ko00002,ko00194	-	-	-	Cytochrom_B559
k141_4492_3	35128.Thapsdraft1387	1.48e-56	175.0	2CHYC@1|root,2S3QA@2759|Eukaryota,2XGKP@2836|Bacillariophyta	2836|Bacillariophyta	C	This b-type cytochrome is tightly associated with the reaction center of photosystem II (PSII). PSII is a light-driven water plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation. It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation	psbE	-	-	ko:K02707	ko00195,ko01100,map00195,map01100	M00161	-	-	ko00000,ko00001,ko00002,ko00194	-	-	-	Cytochrom_B559,Cytochrom_B559a
k141_5716_1	883126.HMPREF9710_00633	1.15e-108	343.0	COG1703@1|root,COG1884@1|root,COG2185@1|root,COG1703@2|Bacteria,COG1884@2|Bacteria,COG2185@2|Bacteria,1MUXX@1224|Proteobacteria,2VIT2@28216|Betaproteobacteria,478JZ@75682|Oxalobacteraceae	28216|Betaproteobacteria	EI	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly	icmF	-	5.4.99.2,5.4.99.63,5.4.99.64	ko:K01847,ko:K01848,ko:K14447,ko:K20906	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R00833,R09292	RC00395,RC02835	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,MM_CoA_mutase
k141_2030_1	1033802.SSPSH_002497	1.37e-29	112.0	COG0558@1|root,COG0558@2|Bacteria,1P1W5@1224|Proteobacteria	1224|Proteobacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	-	-	2.7.8.5	ko:K00995	ko00564,ko01100,map00564,map01100	-	R01801	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
k141_6958_1	1122176.KB903546_gene979	5.48e-67	208.0	COG0694@1|root,COG0694@2|Bacteria,4NG0Q@976|Bacteroidetes,1IQ4T@117747|Sphingobacteriia	976|Bacteroidetes	O	PFAM Scaffold protein Nfu NifU N terminal	-	-	-	-	-	-	-	-	-	-	-	-	Nfu_N,NifU
k141_787_1	159749.E7BWN5	1.45e-138	405.0	COG0201@1|root,2QSNV@2759|Eukaryota	2759|Eukaryota	U	protein transport	secY	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006996,GO:0008150,GO:0009507,GO:0009534,GO:0009535,GO:0009536,GO:0009579,GO:0009657,GO:0009668,GO:0009987,GO:0010027,GO:0016020,GO:0016043,GO:0031976,GO:0031984,GO:0034357,GO:0042651,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044436,GO:0044444,GO:0044446,GO:0044464,GO:0055035,GO:0061024,GO:0071840	-	ko:K10956	ko03060,ko04141,ko04145,ko05110,map03060,map04141,map04145,map05110	M00401	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.4,3.A.5.8,3.A.5.9	-	-	SecY
k141_787_2	159749.E7BWN4	8.44e-86	256.0	COG0098@1|root,KOG0877@2759|Eukaryota	2759|Eukaryota	J	structural constituent of ribosome	rps5	GO:0000313,GO:0000314,GO:0003002,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005739,GO:0005759,GO:0005761,GO:0005763,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006950,GO:0006996,GO:0007275,GO:0007389,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009409,GO:0009507,GO:0009532,GO:0009534,GO:0009535,GO:0009536,GO:0009570,GO:0009579,GO:0009628,GO:0009657,GO:0009955,GO:0009987,GO:0010035,GO:0010038,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0031974,GO:0031976,GO:0031984,GO:0032501,GO:0032502,GO:0032544,GO:0032991,GO:0034357,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042221,GO:0042254,GO:0042651,GO:0043043,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044429,GO:0044434,GO:0044435,GO:0044436,GO:0044444,GO:0044446,GO:0044464,GO:0046483,GO:0046686,GO:0048856,GO:0050896,GO:0055035,GO:0070013,GO:0071704,GO:0071840,GO:0090304,GO:0098798,GO:1901259,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02988	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S5,Ribosomal_S5_C
k141_8770_1	1116472.MGMO_17c00180	1.28e-75	250.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1MUT8@1224|Proteobacteria,1RN6R@1236|Gammaproteobacteria,1XDY0@135618|Methylococcales	135618|Methylococcales	G	Belongs to the PEP-utilizing enzyme family	ppdK	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
k141_4493_1	886293.Sinac_7397	6.9e-101	309.0	COG1861@1|root,COG1861@2|Bacteria,2J3F7@203682|Planctomycetes	203682|Planctomycetes	M	PFAM Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_4
k141_2031_1	639283.Snov_1675	2.38e-99	314.0	COG0178@1|root,COG0178@2|Bacteria,1MW0W@1224|Proteobacteria,2TQK9@28211|Alphaproteobacteria,3EYWG@335928|Xanthobacteraceae	28211|Alphaproteobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
k141_6959_1	383381.EH30_01975	7.91e-11	62.8	COG3749@1|root,COG3749@2|Bacteria,1RJR9@1224|Proteobacteria,2UA02@28211|Alphaproteobacteria,2K4PM@204457|Sphingomonadales	204457|Sphingomonadales	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF934
k141_169_1	35128.Thapsdraft1611	6.47e-157	458.0	28JJ8@1|root,2QRYE@2759|Eukaryota,2XEB4@2836|Bacillariophyta	2836|Bacillariophyta	C	PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX. PSI is a plastocyanin cytochrome c6-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn. Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin or cytochrome c6	psaB	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009534,GO:0009535,GO:0009536,GO:0009579,GO:0016020,GO:0016168,GO:0031976,GO:0031984,GO:0034357,GO:0042651,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044436,GO:0044444,GO:0044446,GO:0044464,GO:0046906,GO:0048037,GO:0055035,GO:0097159,GO:1901363	-	ko:K02690	ko00195,ko01100,map00195,map01100	M00163	-	-	ko00000,ko00001,ko00002,ko00194	-	-	-	PsaA_PsaB
k141_6344_1	1131269.AQVV01000004_gene632	6.97e-49	172.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF4114
k141_9429_1	1354722.JQLS01000008_gene651	1.72e-48	156.0	COG1734@1|root,COG1734@2|Bacteria,1N8K6@1224|Proteobacteria,2UCF1@28211|Alphaproteobacteria,46R0X@74030|Roseovarius	28211|Alphaproteobacteria	T	Prokaryotic dksA/traR C4-type zinc finger	dskA	-	-	-	-	-	-	-	-	-	-	-	zf-dskA_traR
k141_8772_2	765911.Thivi_2388	4.76e-29	110.0	COG0253@1|root,COG0253@2|Bacteria,1MWDH@1224|Proteobacteria,1RMGV@1236|Gammaproteobacteria,1WVYQ@135613|Chromatiales	135613|Chromatiales	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	dapF	-	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	DAP_epimerase
k141_2033_1	1313301.AUGC01000012_gene1320	3.14e-67	212.0	COG0300@1|root,COG0300@2|Bacteria,4NEMK@976|Bacteroidetes	976|Bacteroidetes	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
k141_5111_1	570967.JMLV01000001_gene2788	3.43e-71	235.0	COG0317@1|root,COG0317@2|Bacteria,1MU44@1224|Proteobacteria,2TQNY@28211|Alphaproteobacteria,2JPK1@204441|Rhodospirillales	204441|Rhodospirillales	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	relA	-	2.7.6.5	ko:K00951	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
k141_5720_1	1122180.Lokhon_01289	3.02e-81	256.0	COG0114@1|root,COG0114@2|Bacteria,1MUQI@1224|Proteobacteria,2TQM7@28211|Alphaproteobacteria,2P8X5@245186|Loktanella	28211|Alphaproteobacteria	C	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate	fumC	GO:0003674,GO:0003824,GO:0004333,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006106,GO:0006108,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350	4.2.1.2	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	M00009,M00011,M00173,M00376	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	FumaraseC_C,Lyase_1
k141_6962_1	1238182.C882_1477	1.6e-91	275.0	COG0559@1|root,COG0559@2|Bacteria,1MYEW@1224|Proteobacteria,2TQQZ@28211|Alphaproteobacteria,2JRFC@204441|Rhodospirillales	204441|Rhodospirillales	E	Branched-chain amino acid transport system / permease component	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
k141_7529_1	720554.Clocl_2665	1.04e-61	213.0	COG0318@1|root,COG0318@2|Bacteria,1UZQF@1239|Firmicutes,25ECZ@186801|Clostridia,3WJ0C@541000|Ruminococcaceae	186801|Clostridia	IQ	Phosphopantetheine attachment site	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,KR,PP-binding
k141_2034_1	425104.Ssed_1747	1.52e-66	228.0	COG0366@1|root,COG1409@1|root,COG0366@2|Bacteria,COG1409@2|Bacteria,1PKTM@1224|Proteobacteria,1RWFT@1236|Gammaproteobacteria,2QDDA@267890|Shewanellaceae	1236|Gammaproteobacteria	G	Bacterial Ig-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,Metallophos,Pur_ac_phosph_N
k141_6346_1	2340.JV46_19510	7.28e-129	375.0	COG0436@1|root,COG0436@2|Bacteria,1MX43@1224|Proteobacteria,1RZ0G@1236|Gammaproteobacteria,1JAJY@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	E	Cys/Met metabolism PLP-dependent enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
k141_3250_1	455436.DS989811_gene1713	8.73e-59	184.0	2AU0F@1|root,31JKB@2|Bacteria,1RGGF@1224|Proteobacteria,1S5B2@1236|Gammaproteobacteria,466CW@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	COG NOG14600 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_793_1	1219031.BBJR01000050_gene1637	1.87e-82	259.0	COG1012@1|root,COG1012@2|Bacteria,1MUHV@1224|Proteobacteria,2VI0N@28216|Betaproteobacteria,4A9T8@80864|Comamonadaceae	28216|Betaproteobacteria	C	TIGRFAM methylmalonate-semialdehyde dehydrogenase	-	-	1.2.1.18,1.2.1.27	ko:K00140	ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200	M00013	R00705,R00706,R00922,R00935	RC00004,RC02723,RC02817	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
k141_6429_1	99598.Cal7507_1888	6.97e-25	95.9	COG0335@1|root,COG0335@2|Bacteria,1G5QG@1117|Cyanobacteria,1HNFQ@1161|Nostocales	1117|Cyanobacteria	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	rplS	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
k141_5190_2	1286632.P278_14900	1.86e-08	56.6	2DMPB@1|root,32SV8@2|Bacteria,4NSG4@976|Bacteroidetes,1I3FJ@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_2722_2	713586.KB900536_gene1021	3.37e-17	79.0	COG0437@1|root,COG0437@2|Bacteria,1NBU3@1224|Proteobacteria,1RRYZ@1236|Gammaproteobacteria,1WVZM@135613|Chromatiales	135613|Chromatiales	C	PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein	-	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_11,Fer4_7
k141_8231_1	159749.K0SXC9	4.78e-126	416.0	29N4Q@1|root,2RVF7@2759|Eukaryota,2XBJX@2836|Bacillariophyta	159749.K0SXC9|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_5800_1	367336.OM2255_04090	2.83e-53	172.0	COG0047@1|root,COG0047@2|Bacteria,1MU4Y@1224|Proteobacteria,2TS67@28211|Alphaproteobacteria	28211|Alphaproteobacteria	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purQ	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase_5
k141_5800_2	391613.RTM1035_07744	3.67e-32	113.0	COG1828@1|root,COG1828@2|Bacteria,1N83G@1224|Proteobacteria,2UF7S@28211|Alphaproteobacteria,46R5S@74030|Roseovarius	28211|Alphaproteobacteria	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purS	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	PurS
k141_9500_1	745411.B3C1_11469	8.65e-43	154.0	COG0733@1|root,COG0733@2|Bacteria,1MUZJ@1224|Proteobacteria,1RPCT@1236|Gammaproteobacteria,1J5IR@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	U	Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family	-	-	-	ko:K03308	-	-	-	-	ko00000	2.A.22.4,2.A.22.5	-	-	SNF
k141_1489_1	648885.KB316283_gene3067	1.33e-72	230.0	COG1533@1|root,COG1533@2|Bacteria,1MW0H@1224|Proteobacteria,2TQQB@28211|Alphaproteobacteria,1JRVU@119045|Methylobacteriaceae	28211|Alphaproteobacteria	L	SMART Elongator protein 3 MiaB NifB	MA20_42330	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
k141_251_1	1381751.JAJB01000015_gene2199	1.13e-19	95.5	COG1042@1|root,COG1042@2|Bacteria,2GKN1@201174|Actinobacteria,4F8DM@85019|Brevibacteriaceae	201174|Actinobacteria	C	CoA binding domain	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_5,CoA_binding_2,Succ_CoA_lig
k141_4488_1	1122180.Lokhon_02898	8.15e-19	84.3	2CGGD@1|root,32S3Y@2|Bacteria,1N74K@1224|Proteobacteria,2UFXV@28211|Alphaproteobacteria,2P95F@245186|Loktanella	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4177
k141_2639_1	1198232.CYCME_0386	2.8e-142	421.0	COG0480@1|root,COG0480@2|Bacteria,1MUCV@1224|Proteobacteria,1RNNJ@1236|Gammaproteobacteria,4607G@72273|Thiotrichales	72273|Thiotrichales	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	-	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
k141_5102_1	1379270.AUXF01000001_gene1915	2.62e-58	197.0	COG1502@1|root,COG1502@2|Bacteria	2|Bacteria	I	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol	CP_0318	-	-	ko:K06131,ko:K06132	ko00564,ko01100,map00564,map01100	-	R07390,R11062	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2
k141_3243_1	768671.ThimaDRAFT_4388	2.83e-34	130.0	COG1205@1|root,COG1205@2|Bacteria,1QU0I@1224|Proteobacteria,1S0XD@1236|Gammaproteobacteria,1WXNC@135613|Chromatiales	135613|Chromatiales	L	DEAD DEAH box	-	-	-	ko:K06877	-	-	-	-	ko00000	-	-	-	DEAD,DUF1998,Helicase_C
k141_3243_2	545276.KB898733_gene2547	3.1e-77	250.0	COG1205@1|root,COG1205@2|Bacteria,1QU0I@1224|Proteobacteria,1S0XD@1236|Gammaproteobacteria,1WXNC@135613|Chromatiales	135613|Chromatiales	L	DEAD DEAH box	-	-	-	ko:K06877	-	-	-	-	ko00000	-	-	-	DEAD,DUF1998,Helicase_C
k141_6337_1	986075.CathTA2_0069	7.26e-105	323.0	COG3344@1|root,COG3344@2|Bacteria,1TP9A@1239|Firmicutes,4H9NW@91061|Bacilli	91061|Bacilli	L	reverse transcriptase	-	-	-	-	-	-	-	-	-	-	-	-	GIIM,RVT_1
k141_784_1	570952.ATVH01000013_gene2650	1.29e-78	260.0	COG1196@1|root,COG1196@2|Bacteria,1MUAQ@1224|Proteobacteria,2TRQG@28211|Alphaproteobacteria,2JQ9K@204441|Rhodospirillales	204441|Rhodospirillales	D	Required for chromosome condensation and partitioning	smc	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N
k141_4489_1	553385.JEMF01000002_gene2837	1.05e-20	87.8	COG2166@1|root,COG2166@2|Bacteria,1RI8F@1224|Proteobacteria,1S65C@1236|Gammaproteobacteria,1XK9I@135619|Oceanospirillales	135619|Oceanospirillales	S	SufE protein probably involved in Fe-S center assembly	sufE	-	-	ko:K02426	-	-	-	-	ko00000	-	-	-	SufE
k141_4524_1	227086.JGI_V11_26979	2.5e-07	52.4	COG0099@1|root,KOG3311@2759|Eukaryota	2759|Eukaryota	J	rRNA binding	rps13	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
k141_6374_1	309807.SRU_2686	1.65e-56	194.0	COG0661@1|root,COG0661@2|Bacteria,4NDUP@976|Bacteroidetes,1FJEM@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	ABC1 family	-	-	-	ko:K03688	-	-	-	-	ko00000	-	-	-	ABC1
k141_199_1	519442.Huta_1362	3.3e-22	99.0	COG0113@1|root,arCOG04300@2157|Archaea,2XSZ8@28890|Euryarchaeota,23S4G@183963|Halobacteria	183963|Halobacteria	H	Belongs to the ALAD family	hemB	-	4.2.1.24	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00036	RC00918,RC01781	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ALAD
k141_5749_1	1250005.PHEL85_3265	9.94e-103	327.0	COG0495@1|root,COG0495@2|Bacteria,4NE5K@976|Bacteroidetes,1HY4A@117743|Flavobacteriia,3VVGU@52959|Polaribacter	976|Bacteroidetes	J	Leucyl-tRNA synthetase, Domain 2	leuS	GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,DUF559,tRNA-synt_1,tRNA-synt_1_2
k141_823_1	436308.Nmar_1653	2.78e-35	126.0	COG1108@1|root,arCOG01006@2157|Archaea,41SG2@651137|Thaumarchaeota	651137|Thaumarchaeota	P	ABC 3 transport family	-	-	-	ko:K09816	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ABC-3
k141_823_2	1229909.NSED_08955	2.42e-92	274.0	COG1121@1|root,arCOG00201@2157|Archaea,41S7E@651137|Thaumarchaeota	651137|Thaumarchaeota	E	PFAM ABC transporter	-	-	-	ko:K09817	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ABC_tran
k141_7551_1	159749.E7BWK4	1.35e-107	318.0	28IP8@1|root,2QR09@2759|Eukaryota,2XF0J@2836|Bacillariophyta	2836|Bacillariophyta	C	Photosynthetic reaction centre protein	psbA	-	1.10.3.9	ko:K02703	ko00195,ko01100,map00195,map01100	M00161	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	-	-	-	Photo_RC
k141_7551_2	159749.E7BWK5	9.63e-20	87.8	COG1333@1|root,2QRFF@2759|Eukaryota	2759|Eukaryota	O	cytochrome complex assembly	ccs1	-	-	ko:K07399	-	-	-	-	ko00000	-	-	-	ResB
k141_2675_1	391593.RCCS2_11969	1.36e-130	379.0	COG1035@1|root,COG1035@2|Bacteria,1MWJC@1224|Proteobacteria,2TVFE@28211|Alphaproteobacteria,2P1XK@2433|Roseobacter	28211|Alphaproteobacteria	C	Coenzyme F420 hydrogenase/dehydrogenase, beta subunit N-term	frhB	-	1.12.98.1	ko:K00441	ko00680,ko01100,ko01120,map00680,map01100,map01120	-	R03025	RC02628	ko00000,ko00001,ko01000	-	-	-	FrhB_FdhB_C,FrhB_FdhB_N
k141_1436_1	1049564.TevJSym_ax00200	5.63e-54	179.0	COG1085@1|root,COG1085@2|Bacteria,1MU3E@1224|Proteobacteria,1SJJV@1236|Gammaproteobacteria,1J77S@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	H	Galactose-1-phosphate uridyl transferase, N-terminal domain	galT	-	-	-	-	-	-	-	-	-	-	-	DUF4921,GalP_UDP_tr_C,GalP_UDP_transf
k141_201_1	926550.CLDAP_29120	1.85e-96	288.0	COG0667@1|root,COG0667@2|Bacteria,2G5V3@200795|Chloroflexi	200795|Chloroflexi	C	PFAM aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
k141_8799_1	351016.RAZWK3B_19386	1.2e-12	64.7	2DMH1@1|root,32RGM@2|Bacteria,1RJJQ@1224|Proteobacteria,2UAB5@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_8799_2	314232.SKA53_13666	6.03e-12	68.9	COG0699@1|root,COG0699@2|Bacteria,1R93D@1224|Proteobacteria,2U0MH@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	GTPases (dynamin-related)	-	-	-	-	-	-	-	-	-	-	-	-	Dynamin_N,MMR_HSR1
k141_5750_1	1499967.BAYZ01000012_gene2484	7.77e-28	106.0	COG4577@1|root,COG4577@2|Bacteria	2|Bacteria	CQ	ethanolamine catabolic process	-	-	-	-	-	-	-	-	-	-	-	-	BMC
k141_5750_2	1405498.SSIM_13425	5.36e-29	110.0	COG0274@1|root,COG0274@2|Bacteria,1TPAJ@1239|Firmicutes,4HAAJ@91061|Bacilli,4GY02@90964|Staphylococcaceae	91061|Bacilli	F	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate	deoC	GO:0003674,GO:0003824,GO:0004139,GO:0005975,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009262,GO:0009264,GO:0009987,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576	4.1.2.4	ko:K01619	ko00030,map00030	-	R01066	RC00436,RC00437	ko00000,ko00001,ko01000	-	-	iSB619.SA_RS00835	DeoC
k141_9455_1	159749.K0RF56	2.72e-57	180.0	28NVH@1|root,2QVFH@2759|Eukaryota,2XFNZ@2836|Bacillariophyta	2836|Bacillariophyta	C	Photosystem I reaction centre subunit XI	psaL	-	-	ko:K02699	ko00195,ko01100,map00195,map01100	-	-	-	ko00000,ko00001,ko00194	-	-	-	PsaL
k141_2057_1	396588.Tgr7_3313	2.55e-66	211.0	COG1475@1|root,COG1475@2|Bacteria,1MW2E@1224|Proteobacteria,1RN65@1236|Gammaproteobacteria,1WWNZ@135613|Chromatiales	135613|Chromatiales	K	Belongs to the ParB family	-	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
k141_4527_1	159749.E7BWE0	1.96e-55	182.0	COG0805@1|root,2QVCB@2759|Eukaryota	2759|Eukaryota	U	protein transport by the Tat complex	tatC	GO:0000003,GO:0003674,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006810,GO:0006886,GO:0006996,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009507,GO:0009534,GO:0009535,GO:0009536,GO:0009566,GO:0009567,GO:0009579,GO:0009657,GO:0009668,GO:0009977,GO:0009987,GO:0010027,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0019953,GO:0022414,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0031360,GO:0031361,GO:0031976,GO:0031984,GO:0032991,GO:0033036,GO:0033281,GO:0034357,GO:0034613,GO:0042651,GO:0042886,GO:0042887,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043235,GO:0043953,GO:0044422,GO:0044424,GO:0044425,GO:0044434,GO:0044435,GO:0044436,GO:0044444,GO:0044446,GO:0044459,GO:0044464,GO:0044703,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0051704,GO:0055035,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0098796,GO:0098797,GO:1904680	-	ko:K02634,ko:K03118	ko00195,ko01100,ko03060,ko03070,map00195,map01100,map03060,map03070	M00162,M00336	-	-	ko00000,ko00001,ko00002,ko00194,ko02044	2.A.64	-	-	TatC
k141_202_1	1415779.JOMH01000001_gene444	2.05e-09	58.5	COG1028@1|root,COG1028@2|Bacteria,1MUUV@1224|Proteobacteria,1RMJU@1236|Gammaproteobacteria,1X51Z@135614|Xanthomonadales	135614|Xanthomonadales	IQ	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	-	-	1.5.1.33	ko:K03793	-	-	-	-	ko00000,ko01000	-	-	-	adh_short_C2
k141_202_2	102129.Lepto7375DRAFT_2176	1e-07	53.9	COG0596@1|root,COG0596@2|Bacteria,1G2GI@1117|Cyanobacteria	1117|Cyanobacteria	S	Alpha/beta hydrolase family	-	-	3.8.1.5	ko:K01563	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05284,R05367,R05368,R05369,R05370,R07669,R07670	RC01317,RC01340,RC01341,RC02013	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1
k141_3277_1	935840.JAEQ01000001_gene2976	1.59e-71	236.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,2TR2W@28211|Alphaproteobacteria,43IM3@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	IQ	AMP-binding enzyme C-terminal domain	fadD	GO:0001676,GO:0003674,GO:0003824,GO:0004467,GO:0005488,GO:0005504,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006163,GO:0006629,GO:0006631,GO:0006635,GO:0006637,GO:0006644,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009056,GO:0009058,GO:0009062,GO:0009117,GO:0009150,GO:0009259,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009898,GO:0009987,GO:0015645,GO:0016020,GO:0016042,GO:0016054,GO:0016405,GO:0016874,GO:0016877,GO:0016878,GO:0019395,GO:0019637,GO:0019693,GO:0019752,GO:0030258,GO:0031406,GO:0032787,GO:0033293,GO:0033865,GO:0033875,GO:0034032,GO:0034440,GO:0034641,GO:0035383,GO:0036041,GO:0036094,GO:0043167,GO:0043168,GO:0043177,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044249,GO:0044255,GO:0044281,GO:0044282,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0046395,GO:0046483,GO:0050896,GO:0051186,GO:0055086,GO:0055114,GO:0070538,GO:0071704,GO:0071944,GO:0072329,GO:0072521,GO:0090407,GO:0098552,GO:0098562,GO:1901135,GO:1901360,GO:1901564,GO:1901575,GO:1901576	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
k141_8800_1	1177154.Y5S_01949	4.94e-51	170.0	COG0218@1|root,COG0218@2|Bacteria,1MY3Z@1224|Proteobacteria,1RNJP@1236|Gammaproteobacteria,1XJCE@135619|Oceanospirillales	135619|Oceanospirillales	D	Necessary for normal cell division and for the maintenance of normal septation	engB	-	-	ko:K03978	-	-	-	-	ko00000,ko03036	-	-	-	MMR_HSR1
k141_2677_1	1267005.KB911263_gene1340	7.79e-37	142.0	COG0204@1|root,COG0318@1|root,COG0204@2|Bacteria,COG0318@2|Bacteria,1MWDY@1224|Proteobacteria,2TTGI@28211|Alphaproteobacteria,3N9E8@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	I	Phosphate acyltransferases	aas	-	2.3.1.40,6.2.1.20	ko:K05939	ko00071,ko00564,map00071,map00564	-	R01406,R04864	RC00014,RC00039,RC00041	ko00000,ko00001,ko01000	-	-	-	AMP-binding,Acyltransferase,MFS_1
k141_2058_1	28258.KP05_14345	9.09e-38	145.0	COG3419@1|root,COG3419@2|Bacteria,1NUAV@1224|Proteobacteria,1RPV3@1236|Gammaproteobacteria,1XISX@135619|Oceanospirillales	135619|Oceanospirillales	NU	Tfp pilus assembly protein, tip-associated adhesin PilY1	-	-	-	ko:K02674	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	Neisseria_PilC
k141_9457_1	7029.ACYPI009432-PA	5.86e-08	55.8	COG2801@1|root,KOG0017@2759|Eukaryota,38F42@33154|Opisthokonta,3BA5H@33208|Metazoa,3CZSS@33213|Bilateria,4225E@6656|Arthropoda,3SQX6@50557|Insecta	33208|Metazoa	L	K02A2.6-like	-	-	-	-	-	-	-	-	-	-	-	-	MULE,RVT_1,gag-asp_proteas,rve
k141_9457_2	6326.BUX.s00116.914	1.57e-20	94.4	COG2801@1|root,KOG0017@2759|Eukaryota,38F42@33154|Opisthokonta,3BA5H@33208|Metazoa,3CZSS@33213|Bilateria,40FA2@6231|Nematoda,1KXU9@119089|Chromadorea	33208|Metazoa	L	K02A2.6-like	-	-	-	-	-	-	-	-	-	-	-	-	Asp_protease_2,RVT_1,gag-asp_proteas,rve,zf-CCHC
k141_3899_1	56110.Oscil6304_0825	2.54e-44	147.0	COG0292@1|root,COG0292@2|Bacteria,1G5NZ@1117|Cyanobacteria,1HAZX@1150|Oscillatoriales	1117|Cyanobacteria	J	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit	rplT	GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904	-	ko:K02887	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L20
k141_3899_2	159749.E7BWH7	2.98e-27	100.0	2E9KB@1|root,2SFXQ@2759|Eukaryota	2759|Eukaryota	J	Ribosomal protein L35	rpl35	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009536,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464	-	-	-	-	-	-	-	-	-	-	Ribosomal_L35p
k141_3899_3	35128.Thapsdraft308	5.91e-06	44.7	2E6G4@1|root,2S9HV@2759|Eukaryota,2XH2Q@2836|Bacillariophyta	2836|Bacillariophyta	S	Photosystem I reaction centre subunit IV / PsaE	-	-	-	ko:K02693	ko00195,ko01100,map00195,map01100	M00163	-	-	ko00000,ko00001,ko00002,ko00194	-	-	-	PSI_PsaE
k141_6994_1	930169.B5T_04315	1.27e-67	212.0	COG0842@1|root,COG0842@2|Bacteria,1MUH1@1224|Proteobacteria,1RP0Z@1236|Gammaproteobacteria,1XHEP@135619|Oceanospirillales	135619|Oceanospirillales	V	Transport permease protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
k141_6994_2	523791.Kkor_1989	1.53e-26	109.0	COG1033@1|root,COG1033@2|Bacteria,1MUE1@1224|Proteobacteria,1RN01@1236|Gammaproteobacteria,1XIAS@135619|Oceanospirillales	135619|Oceanospirillales	S	of the RND superfamily	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
k141_2679_1	754477.Q7C_1799	3.79e-86	266.0	COG0621@1|root,COG0621@2|Bacteria,1MURS@1224|Proteobacteria,1RMD8@1236|Gammaproteobacteria,45ZTA@72273|Thiotrichales	72273|Thiotrichales	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
k141_205_1	999141.GME_18238	2.47e-38	129.0	COG1145@1|root,COG1145@2|Bacteria,1MZ6H@1224|Proteobacteria,1S8ZV@1236|Gammaproteobacteria,1XKGB@135619|Oceanospirillales	135619|Oceanospirillales	C	Ferredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Fer4
k141_205_2	717773.Thicy_0272	4.97e-48	158.0	COG0669@1|root,COG0669@2|Bacteria,1RD9F@1224|Proteobacteria,1S41J@1236|Gammaproteobacteria,460XS@72273|Thiotrichales	72273|Thiotrichales	H	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	-	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
k141_9458_1	402777.KB235903_gene430	3.94e-20	82.4	2AFZF@1|root,3163A@2|Bacteria,1GG27@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_7555_1	521674.Plim_0176	2.25e-85	265.0	COG0055@1|root,COG0055@2|Bacteria,2IY7P@203682|Planctomycetes	203682|Planctomycetes	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
k141_829_1	580332.Slit_2403	5.34e-34	121.0	COG0440@1|root,COG0440@2|Bacteria,1RAGN@1224|Proteobacteria,2VH1H@28216|Betaproteobacteria,44VPP@713636|Nitrosomonadales	28216|Betaproteobacteria	E	ACT domain	ilvH	GO:0003674,GO:0003824,GO:0003984,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005948,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234	2.2.1.6	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT_5,ALS_ss_C
k141_829_2	1304275.C41B8_08590	5.49e-08	55.5	COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,1RMQQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	H	acetolactate synthase	ilvI	GO:0000287,GO:0003674,GO:0003824,GO:0003984,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0019842,GO:0030976,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901681	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	iAPECO1_1312.APECO1_1907,iB21_1397.B21_00078,iBWG_1329.BWG_0073,iECBD_1354.ECBD_3539,iECB_1328.ECB_00079,iECD_1391.ECD_00079,iUTI89_1310.UTI89_C0085,iYL1228.KPN_00082	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
k141_9459_1	1047013.AQSP01000103_gene1160	3.8e-73	240.0	COG1770@1|root,COG1770@2|Bacteria,2NNMF@2323|unclassified Bacteria	2|Bacteria	E	Prolyl oligopeptidase, N-terminal beta-propeller domain	ptrB	GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0070011,GO:0070012,GO:0071704,GO:0140096,GO:1901564	3.4.21.83	ko:K01354	ko05142,ko05143,map05142,map05143	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S9,Peptidase_S9_N
k141_5146_1	610130.Closa_1194	2.51e-06	54.7	COG2755@1|root,COG2755@2|Bacteria,1VB5D@1239|Firmicutes,25GFQ@186801|Clostridia	186801|Clostridia	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	DUF4886
k141_6996_1	1242864.D187_001133	9.86e-44	157.0	COG3268@1|root,COG3268@2|Bacteria,1MVI3@1224|Proteobacteria,431ET@68525|delta/epsilon subdivisions,2WWV2@28221|Deltaproteobacteria,2YX5R@29|Myxococcales	28221|Deltaproteobacteria	S	Saccharopine dehydrogenase NADP binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Sacchrp_dh_NADP
k141_6382_1	1316936.K678_14632	3.68e-101	326.0	COG0086@1|root,COG0739@1|root,COG0086@2|Bacteria,COG0739@2|Bacteria,1MU3M@1224|Proteobacteria,2TRHV@28211|Alphaproteobacteria,2JQ0E@204441|Rhodospirillales	204441|Rhodospirillales	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	-	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
k141_5756_1	998088.B565_0757	8.53e-87	266.0	COG0407@1|root,COG0407@2|Bacteria,1MUG1@1224|Proteobacteria,1RMDH@1236|Gammaproteobacteria,1Y46X@135624|Aeromonadales	135624|Aeromonadales	H	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III	hemE	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
k141_831_2	1286171.EAL2_808p02740	5.39e-08	58.2	COG3344@1|root,COG3344@2|Bacteria,1TP9A@1239|Firmicutes,248M4@186801|Clostridia,25XSM@186806|Eubacteriaceae	186801|Clostridia	L	Group II intron, maturase-specific domain	ltrA	-	-	-	-	-	-	-	-	-	-	-	GIIM,RVT_1
k141_7556_1	314345.SPV1_09909	5.34e-30	109.0	COG0048@1|root,COG0048@2|Bacteria,1RCWY@1224|Proteobacteria	1224|Proteobacteria	J	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit	rpsL	GO:0000372,GO:0000375,GO:0000376,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008380,GO:0009058,GO:0009059,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010604,GO:0010628,GO:0015935,GO:0016070,GO:0019219,GO:0019222,GO:0019538,GO:0019843,GO:0022626,GO:0022627,GO:0031323,GO:0031325,GO:0032991,GO:0033120,GO:0034336,GO:0034337,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043484,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045935,GO:0046483,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990145,GO:1990904	-	ko:K02950	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosom_S12_S23
k141_4531_1	1229909.NSED_09200	7.2e-141	399.0	COG0638@1|root,arCOG00970@2157|Archaea,41T1N@651137|Thaumarchaeota	651137|Thaumarchaeota	O	Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation	-	-	3.4.25.1	ko:K03433	ko03050,map03050	M00342,M00343	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03051	-	-	-	Proteasome
k141_4531_2	1229909.NSED_09195	1.93e-112	341.0	COG1782@1|root,arCOG00543@2157|Archaea,41T05@651137|Thaumarchaeota	651137|Thaumarchaeota	S	RNA-metabolising metallo-beta-lactamase	-	-	-	ko:K07041	-	-	-	-	ko00000	-	-	-	Beta-Casp,KH_7,Lactamase_B_6,RMMBL
k141_9461_1	616991.JPOO01000003_gene2671	5.29e-109	318.0	COG1418@1|root,COG1418@2|Bacteria,4NEZY@976|Bacteroidetes,1HX55@117743|Flavobacteriia,23FQM@178469|Arenibacter	976|Bacteroidetes	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	ko:K06950	-	-	-	-	ko00000	-	-	-	HD
k141_8194_1	400682.PAC_15706553	2.11e-59	192.0	COG3324@1|root,2SZND@2759|Eukaryota	2759|Eukaryota	S	Glyoxalase-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
k141_3964_1	1071400.LBUCD034_1602	1.24e-23	99.8	COG1484@1|root,COG1484@2|Bacteria,1TPPI@1239|Firmicutes,4HD0T@91061|Bacilli,3FB7E@33958|Lactobacillaceae	91061|Bacilli	L	Bacterial dnaA  protein	-	-	-	-	-	-	-	-	-	-	-	-	IstB_IS21
k141_8246_1	765912.Thimo_2840	1.58e-89	277.0	COG0201@1|root,COG0201@2|Bacteria,1MVU7@1224|Proteobacteria,1RNJV@1236|Gammaproteobacteria,1WWJA@135613|Chromatiales	135613|Chromatiales	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	-	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
k141_3337_1	330779.Saci_1109	0.000303	44.7	COG1250@1|root,arCOG00249@2157|Archaea,2XPQ7@28889|Crenarchaeota	28889|Crenarchaeota	I	3-hydroxyacyl-CoA dehydrogenase	-	-	1.1.1.35,4.2.1.17	ko:K15016	ko00720,ko01120,ko01200,map00720,map01120,map01200	M00374,M00375	R01975,R03026	RC00117,RC00831	ko00000,ko00001,ko00002,ko01000	-	-	-	3HCDH,3HCDH_N,ECH_1
k141_3337_2	644282.Deba_0088	1.6e-62	204.0	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,42RU7@68525|delta/epsilon subdivisions,2WNTU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	Belongs to the thiolase family	-	-	2.3.1.16,2.3.1.9	ko:K00626,ko:K00632	ko00071,ko00072,ko00280,ko00281,ko00310,ko00362,ko00380,ko00592,ko00620,ko00630,ko00640,ko00642,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00281,map00310,map00362,map00380,map00592,map00620,map00630,map00640,map00642,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00087,M00088,M00095,M00113,M00373,M00374,M00375	R00238,R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
k141_5816_1	207954.MED92_02269	2.91e-83	254.0	arCOG03638@1|root,2Z8W3@2|Bacteria,1N2PH@1224|Proteobacteria,1RMI8@1236|Gammaproteobacteria,1XHVP@135619|Oceanospirillales	135619|Oceanospirillales	S	Protein of unknown function (DUF1538)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1538
k141_6441_2	926550.CLDAP_25740	7.73e-29	114.0	COG5322@1|root,COG5322@2|Bacteria,2G7SR@200795|Chloroflexi	200795|Chloroflexi	S	oxidoreductase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_2736_1	913325.N799_01330	2.22e-132	409.0	COG1703@1|root,COG1884@1|root,COG2185@1|root,COG1703@2|Bacteria,COG1884@2|Bacteria,COG2185@2|Bacteria,1MUXX@1224|Proteobacteria,1RSHX@1236|Gammaproteobacteria,1X3T3@135614|Xanthomonadales	135614|Xanthomonadales	EI	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly	icmF	-	5.4.99.13	ko:K11942	-	-	-	-	ko00000,ko01000	-	-	-	ArgK,B12-binding,MM_CoA_mutase
k141_9517_1	296587.XP_002506544.1	1.42e-09	58.2	2CR0U@1|root,2R6FS@2759|Eukaryota	2759|Eukaryota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	MTHFR
k141_886_1	1323663.AROI01000006_gene2875	1.27e-94	293.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,1RMBS@1236|Gammaproteobacteria	1236|Gammaproteobacteria	NU	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB	gspE	-	-	ko:K02454	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSE,T2SSE_N
k141_5209_2	1336235.JAEG01000009_gene2860	1.04e-27	114.0	COG1172@1|root,COG1172@2|Bacteria,1PH79@1224|Proteobacteria,2VBDY@28211|Alphaproteobacteria,4BADE@82115|Rhizobiaceae	28211|Alphaproteobacteria	G	Branched-chain amino acid transport system / permease component	-	-	-	ko:K10440	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	BPD_transp_2
k141_2737_3	396588.Tgr7_2496	7.25e-11	63.2	COG0642@1|root,COG2205@2|Bacteria,1N58A@1224|Proteobacteria,1RP34@1236|Gammaproteobacteria,1WYRG@135613|Chromatiales	135613|Chromatiales	T	Histidine kinase	-	-	2.7.13.3	ko:K07711	ko02020,ko02024,map02020,map02024	M00502	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
k141_8863_1	243090.RB2845	7.84e-24	105.0	COG2010@1|root,COG2010@2|Bacteria,2IXDW@203682|Planctomycetes	203682|Planctomycetes	C	Planctomycete cytochrome C	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt2,PSD1
k141_6443_1	1229909.NSED_02600	2.02e-37	133.0	COG1405@1|root,arCOG01981@2157|Archaea,41S8Y@651137|Thaumarchaeota	651137|Thaumarchaeota	K	factor TFIIB	-	-	-	ko:K03124	ko03022,ko05169,ko05203,map03022,map05169,map05203	-	-	-	ko00000,ko00001,ko03021	-	-	-	TFIIB,TF_Zn_Ribbon
k141_6443_2	1229909.NSED_02605	4.06e-46	149.0	COG3277@1|root,arCOG02466@2157|Archaea,41SVG@651137|Thaumarchaeota	651137|Thaumarchaeota	J	RNA-binding protein involved in rRNA processing	-	-	-	ko:K07569	-	-	-	-	ko00000,ko03009	-	-	-	Gar1
k141_1504_1	1121456.ATVA01000003_gene3026	2.33e-42	158.0	COG1042@1|root,COG1042@2|Bacteria,1NU6B@1224|Proteobacteria,42NAU@68525|delta/epsilon subdivisions,2WJHX@28221|Deltaproteobacteria,2M8HI@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	ATP-grasp domain	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_5,CoA_binding_2,Succ_CoA_lig
k141_9519_1	926690.KE386573_gene457	2.71e-22	92.4	arCOG07549@1|root,arCOG07549@2157|Archaea,2XY0C@28890|Euryarchaeota,23WIQ@183963|Halobacteria	183963|Halobacteria	S	Domain of unknown function (DUF4864)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4864
k141_7053_1	159749.K0RL31	2.35e-108	373.0	COG2801@1|root,KOG0017@2759|Eukaryota,2XF4I@2836|Bacillariophyta	159749.K0RL31|-	L	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_5819_1	857087.Metme_0137	2.39e-99	315.0	COG0060@1|root,COG0060@2|Bacteria,1MVBQ@1224|Proteobacteria,1RMTF@1236|Gammaproteobacteria,1XDWG@135618|Methylococcales	135618|Methylococcales	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1,zf-FPG_IleRS
k141_2126_1	371731.Rsw2DRAFT_2900	7.21e-132	384.0	COG0842@1|root,COG0842@2|Bacteria,1MW5R@1224|Proteobacteria,2TU59@28211|Alphaproteobacteria,1FCIQ@1060|Rhodobacter	28211|Alphaproteobacteria	V	ABC-2 family transporter protein	MA20_09460	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
k141_888_1	391165.GbCGDNIH1_1649	3.86e-26	100.0	COG2127@1|root,COG2127@2|Bacteria,1MZU8@1224|Proteobacteria,2U982@28211|Alphaproteobacteria,2JSWP@204441|Rhodospirillales	204441|Rhodospirillales	S	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation	clpS	-	-	ko:K06891	-	-	-	-	ko00000	-	-	-	ClpS
k141_888_2	391165.GbCGDNIH1_1751	2.58e-46	166.0	COG0542@1|root,COG0542@2|Bacteria,1MV8B@1224|Proteobacteria,2TQUZ@28211|Alphaproteobacteria,2JPMS@204441|Rhodospirillales	204441|Rhodospirillales	O	Belongs to the ClpA ClpB family	clpA	-	-	ko:K03694	-	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
k141_4595_1	1286106.MPL1_01453	4.29e-21	87.8	2E4XG@1|root,32ZRD@2|Bacteria,1N79W@1224|Proteobacteria,1SCEN@1236|Gammaproteobacteria,461BY@72273|Thiotrichales	72273|Thiotrichales	S	tryptophan synthase subunit beta	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_5820_1	1121396.KB892900_gene2129	7.17e-15	79.3	COG1657@1|root,COG2374@1|root,COG2931@1|root,COG3291@1|root,COG4733@1|root,COG4932@1|root,COG5306@1|root,COG1657@2|Bacteria,COG2374@2|Bacteria,COG2931@2|Bacteria,COG3291@2|Bacteria,COG4733@2|Bacteria,COG4932@2|Bacteria,COG5306@2|Bacteria,1MWIT@1224|Proteobacteria,42W2M@68525|delta/epsilon subdivisions,2WRTW@28221|Deltaproteobacteria,2MKVR@213118|Desulfobacterales	28221|Deltaproteobacteria	M	PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	PKD,VCBS
k141_273_2	391735.Veis_4968	2.38e-43	147.0	COG1786@1|root,COG1786@2|Bacteria,1RFUH@1224|Proteobacteria,2VSAS@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Protein of unknown function DUF126	-	-	-	ko:K09128	-	-	-	-	ko00000	-	-	-	DUF126
k141_4046_1	159749.K0RA91	4.05e-28	116.0	2D0ZX@1|root,2SG6M@2759|Eukaryota,2XFQF@2836|Bacillariophyta	2836|Bacillariophyta	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_5899_1	1547437.LL06_09305	2.91e-86	263.0	COG0601@1|root,COG0601@2|Bacteria,1MU8Z@1224|Proteobacteria,2TSIY@28211|Alphaproteobacteria,43I9Y@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	EP	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
k141_2813_2	891968.Anamo_0467	5.12e-08	54.7	COG0086@1|root,COG0086@2|Bacteria,3TAAP@508458|Synergistetes	508458|Synergistetes	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	-	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
k141_351_1	351016.RAZWK3B_20281	2.74e-92	290.0	COG0855@1|root,COG0855@2|Bacteria,1MUM3@1224|Proteobacteria,2TRBP@28211|Alphaproteobacteria,2P2AI@2433|Roseobacter	28211|Alphaproteobacteria	H	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
k141_1581_1	1005999.GLGR_1103	6.92e-57	186.0	COG3132@1|root,COG3132@2|Bacteria,1RA13@1224|Proteobacteria,1RQUQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Belongs to the UPF0502 family	yceH	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K09915	-	-	-	-	ko00000	-	-	-	DUF480
k141_7698_1	1380394.JADL01000001_gene2809	8.94e-70	219.0	COG1173@1|root,COG1173@2|Bacteria,1MWMX@1224|Proteobacteria,2TQZR@28211|Alphaproteobacteria,2JPIC@204441|Rhodospirillales	204441|Rhodospirillales	EP	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
k141_966_2	1144275.COCOR_04085	3.7e-57	192.0	COG2072@1|root,COG2072@2|Bacteria,1MU71@1224|Proteobacteria,437U8@68525|delta/epsilon subdivisions,2X33W@28221|Deltaproteobacteria,2YU3R@29|Myxococcales	28221|Deltaproteobacteria	C	Flavin-binding monooxygenase-like	ethA	-	-	-	-	-	-	-	-	-	-	-	FMO-like,NAD_binding_8
k141_2210_1	349124.Hhal_0572	2.2e-61	206.0	COG3263@1|root,COG3263@2|Bacteria,1MVKV@1224|Proteobacteria,1RMCA@1236|Gammaproteobacteria,1WXRK@135613|Chromatiales	135613|Chromatiales	P	Sodium hydrogen exchanger	-	-	-	ko:K11105	-	-	-	-	ko00000,ko02000	2.A.36.6	-	-	CorC_HlyC,Na_H_Exchanger,TrkA_C
k141_9583_2	1449342.JQMR01000001_gene2372	1.32e-19	87.8	COG0517@1|root,COG0517@2|Bacteria,1V7SC@1239|Firmicutes,4HGJP@91061|Bacilli,27G4C@186828|Carnobacteriaceae	91061|Bacilli	S	Domain in cystathionine beta-synthase and other proteins.	acuB	GO:0003674,GO:0003824,GO:0003938,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	-	ko:K04767	-	-	-	-	ko00000	-	-	-	ACT,CBS
k141_5286_1	1353529.M899_2367	1.26e-68	214.0	COG2209@1|root,COG2209@2|Bacteria,1R33S@1224|Proteobacteria,42N3Q@68525|delta/epsilon subdivisions,2WJSA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol	nqrE	-	1.6.5.8	ko:K00350	-	-	-	-	ko00000,ko01000	-	-	-	Rnf-Nqr
k141_4676_1	765910.MARPU_10625	6.47e-48	173.0	COG0557@1|root,COG0557@2|Bacteria,1MUS6@1224|Proteobacteria,1RMQE@1236|Gammaproteobacteria,1WXF0@135613|Chromatiales	135613|Chromatiales	K	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs	rnr	-	-	ko:K12573	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	HTH_12,OB_RNB,RNB,S1
k141_3414_1	395493.BegalDRAFT_1705	3.75e-05	47.0	COG3225@1|root,COG3225@2|Bacteria,1MY63@1224|Proteobacteria,1RP5E@1236|Gammaproteobacteria,461IW@72273|Thiotrichales	72273|Thiotrichales	N	Gliding motility protein GldG	-	-	-	-	-	-	-	-	-	-	-	-	ABC_transp_aux
k141_6521_2	1131269.AQVV01000004_gene599	2.65e-34	132.0	COG3225@1|root,COG3225@2|Bacteria	2|Bacteria	-	-	gldG	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC_transp_aux
k141_8931_1	1424334.W822_20685	4.94e-20	94.4	COG0497@1|root,COG0497@2|Bacteria,1MUNP@1224|Proteobacteria,2VHHA@28216|Betaproteobacteria,3T2NZ@506|Alcaligenaceae	28216|Betaproteobacteria	L	May be involved in recombinational repair of damaged DNA	recN	-	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	SMC_N
k141_354_1	1190603.AJYD01000029_gene4454	9.53e-36	146.0	COG2931@1|root,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,1RNK8@1236|Gammaproteobacteria,1XSBS@135623|Vibrionales	135623|Vibrionales	Q	COG2931 RTX toxins and related Ca2 -binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_7134_2	159749.E7BWC8	1.79e-54	177.0	COG0081@1|root,KOG1569@2759|Eukaryota,2XFIB@2836|Bacillariophyta	2836|Bacillariophyta	J	Binds directly to 23S rRNA. Might be involved in E site tRNA release	-	GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009507,GO:0009536,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	-	-	-	-	-	-	-	-	-	Ribosomal_L1
k141_7701_1	314345.SPV1_05467	8.72e-81	256.0	COG1233@1|root,COG1233@2|Bacteria,1MV2R@1224|Proteobacteria	1224|Proteobacteria	Q	COG1233 Phytoene dehydrogenase and related proteins	-	-	1.3.99.23,5.2.1.13	ko:K09516,ko:K09835	ko00830,ko00906,ko01100,ko01110,map00830,map00906,map01100,map01110	M00097	R07163,R07512	RC01835,RC01960	ko00000,ko00001,ko00002,ko01000	-	-	-	Amino_oxidase,NAD_binding_8
k141_3415_1	856793.MICA_2253	2.06e-16	78.2	COG0681@1|root,COG0681@2|Bacteria,1MXUF@1224|Proteobacteria,2TR9N@28211|Alphaproteobacteria,4BQ0P@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	U	Belongs to the peptidase S26 family	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
k141_3415_2	331869.BAL199_24674	8.07e-36	129.0	COG0571@1|root,COG0571@2|Bacteria,1MUQ6@1224|Proteobacteria,2TTIA@28211|Alphaproteobacteria,4BQBW@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	J	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism	rnc	GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	-	-	-	Ribonucleas_3_3,dsrm
k141_8331_1	631362.Thi970DRAFT_03598	2.99e-88	276.0	COG0511@1|root,COG5016@1|root,COG0511@2|Bacteria,COG5016@2|Bacteria,1QTTG@1224|Proteobacteria,1RNG6@1236|Gammaproteobacteria,1WW0Z@135613|Chromatiales	135613|Chromatiales	CI	TIGRFAM Oxaloacetate decarboxylase, alpha subunit	-	-	4.1.1.3	ko:K01571	ko00620,ko01100,map00620,map01100	-	R00217	RC00040	ko00000,ko00001,ko01000,ko02000	3.B.1.1.1	-	-	Biotin_lipoyl,HMGL-like,PYC_OADA
k141_9586_1	1535422.ND16A_3571	2.87e-12	65.9	COG3547@1|root,COG3547@2|Bacteria,1MUER@1224|Proteobacteria,1RMAQ@1236|Gammaproteobacteria,2Q707@267889|Colwelliaceae	1236|Gammaproteobacteria	L	Transposase	-	-	-	ko:K07486	-	-	-	-	ko00000	-	-	-	DEDD_Tnp_IS110,Transposase_20
k141_4678_1	985054.JQEZ01000001_gene1789	2.76e-70	224.0	COG3547@1|root,COG3547@2|Bacteria,1MUER@1224|Proteobacteria,2TSGZ@28211|Alphaproteobacteria,4NCKA@97050|Ruegeria	28211|Alphaproteobacteria	L	Transposase IS116/IS110/IS902 family	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k141_5290_1	159749.K0RZE4	2.38e-31	127.0	COG2801@1|root,KOG0017@2759|Eukaryota,2XEGG@2836|Bacillariophyta	2836|Bacillariophyta	L	transposition, RNA-mediated	-	-	-	-	-	-	-	-	-	-	-	-	RVT_2,gag_pre-integrs,rve,zf-CCHC
k141_5903_1	1337093.MBE-LCI_0459	6.77e-88	268.0	COG0379@1|root,COG0379@2|Bacteria,1MWQU@1224|Proteobacteria,2TRPG@28211|Alphaproteobacteria,2P9E0@245186|Loktanella	28211|Alphaproteobacteria	H	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate	nadA	-	2.5.1.72	ko:K03517	ko00760,ko01100,map00760,map01100	M00115	R04292	RC01119	ko00000,ko00001,ko00002,ko01000	-	-	-	NadA
k141_3416_1	414684.RC1_1465	6.4e-99	301.0	COG0174@1|root,COG0174@2|Bacteria,1MU6V@1224|Proteobacteria,2TRCP@28211|Alphaproteobacteria,2JQHA@204441|Rhodospirillales	204441|Rhodospirillales	E	Glutamine synthetase, catalytic domain	-	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C
k141_8933_1	1229909.NSED_09540	3.33e-83	250.0	COG1514@1|root,arCOG01736@2157|Archaea,41SP7@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester	-	-	3.1.4.58	ko:K01975	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	LigT_PEase
k141_6522_1	351016.RAZWK3B_11321	2.17e-48	157.0	2AU0F@1|root,31JKB@2|Bacteria,1RGGF@1224|Proteobacteria,2U8PC@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	COG NOG14600 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_356_1	159749.K0SZZ0	8.35e-65	211.0	COG2801@1|root,KOG0017@2759|Eukaryota,2XHT0@2836|Bacillariophyta	159749.K0SZZ0|-	O	transposition, RNA-mediated	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_2211_1	768671.ThimaDRAFT_0847	4.35e-157	465.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,1SA31@1236|Gammaproteobacteria	1224|Proteobacteria	T	SMART ATP-binding region, ATPase-like	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3
k141_2211_2	1510531.JQJJ01000010_gene2235	1.3e-44	155.0	COG4566@1|root,COG4566@2|Bacteria,1R47Z@1224|Proteobacteria,2TSQS@28211|Alphaproteobacteria,3JYF7@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
k141_970_1	159749.E7BWK6	6.85e-159	458.0	COG0464@1|root,KOG0730@2759|Eukaryota	2759|Eukaryota	O	ATP binding	ycf46	-	-	-	-	-	-	-	-	-	-	-	AAA
k141_7136_1	744980.TRICHSKD4_0428	1.04e-88	276.0	COG0069@1|root,COG4638@1|root,COG0069@2|Bacteria,COG4638@2|Bacteria,1MU7B@1224|Proteobacteria,2TRWC@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Belongs to the glutamate synthase family	-	-	-	-	-	-	-	-	-	-	-	-	Glu_synthase,Rieske,zf-CDGSH
k141_5904_1	1250232.JQNJ01000001_gene3055	6.02e-26	108.0	COG3055@1|root,COG3291@1|root,COG3055@2|Bacteria,COG3291@2|Bacteria,4NHHD@976|Bacteroidetes,1HWPE@117743|Flavobacteriia	976|Bacteroidetes	M	Di-glucose binding within endoplasmic reticulum	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG,Kelch_1,Kelch_6,Malectin,PKD
k141_5904_2	472759.Nhal_0469	3.47e-20	88.6	COG0767@1|root,COG0767@2|Bacteria,1MVPN@1224|Proteobacteria,1RYHN@1236|Gammaproteobacteria,1WXIV@135613|Chromatiales	135613|Chromatiales	Q	Permease MlaE	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE,STAS_2
k141_8332_1	768671.ThimaDRAFT_0364	1.03e-76	247.0	COG3046@1|root,COG3046@2|Bacteria,1MUHX@1224|Proteobacteria,1RNUM@1236|Gammaproteobacteria,1WW3E@135613|Chromatiales	135613|Chromatiales	S	Deoxyribodipyrimidine photo-lyase-related protein	-	-	-	ko:K06876	-	-	-	-	ko00000	-	-	-	DPRP
k141_2819_1	570952.ATVH01000013_gene2982	2.68e-35	128.0	COG0131@1|root,COG0131@2|Bacteria,1MWBS@1224|Proteobacteria,2TTVV@28211|Alphaproteobacteria,2JPDI@204441|Rhodospirillales	204441|Rhodospirillales	E	imidazoleglycerol-phosphate dehydratase	hisB	-	4.2.1.19	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03457	RC00932	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPD
k141_2525_1	1121935.AQXX01000117_gene5090	1.02e-87	268.0	COG0547@1|root,COG0547@2|Bacteria,1MUPV@1224|Proteobacteria,1RNXV@1236|Gammaproteobacteria,1XIT8@135619|Oceanospirillales	135619|Oceanospirillales	E	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)	trpD	-	2.4.2.18	ko:K00766	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R01073	RC00440	ko00000,ko00001,ko00002,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3
k141_6222_1	697282.Mettu_0416	3.59e-90	283.0	COG1449@1|root,COG1449@2|Bacteria,1P2YJ@1224|Proteobacteria,1RPDG@1236|Gammaproteobacteria,1XE57@135618|Methylococcales	135618|Methylococcales	G	Belongs to the glycosyl hydrolase 57 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_57
k141_4986_1	305700.B447_14489	1.22e-70	225.0	COG3748@1|root,COG3748@2|Bacteria,1MWHB@1224|Proteobacteria,2VIC0@28216|Betaproteobacteria,2KV1G@206389|Rhodocyclales	206389|Rhodocyclales	S	Pfam:DUF989	-	-	-	-	-	-	-	-	-	-	-	-	Urate_ox_N
k141_9305_1	1089552.KI911559_gene289	8.07e-85	266.0	COG0606@1|root,COG0606@2|Bacteria,1MU4R@1224|Proteobacteria,2TQU6@28211|Alphaproteobacteria,2JP8C@204441|Rhodospirillales	204441|Rhodospirillales	O	ATPase with chaperone activity	-	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
k141_8055_1	1229909.NSED_01675	2.78e-131	405.0	COG0086@1|root,arCOG04256@2157|Archaea,arCOG04257@2157|Archaea,41SB2@651137|Thaumarchaeota	651137|Thaumarchaeota	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA2	-	2.7.7.6	ko:K03041	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00184	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
k141_1288_1	2850.Phatrdraft1240	1.3e-141	455.0	COG2801@1|root,KOG0017@2759|Eukaryota,2XEGG@2836|Bacillariophyta	2836|Bacillariophyta	L	transposition, RNA-mediated	-	-	-	-	-	-	-	-	-	-	-	-	RVT_2,gag_pre-integrs,rve,zf-CCHC
k141_3749_1	439235.Dalk_1994	5.6e-39	147.0	COG1032@1|root,COG1032@2|Bacteria,1MY2Y@1224|Proteobacteria,42NG3@68525|delta/epsilon subdivisions,2WJ95@28221|Deltaproteobacteria,2MJ57@213118|Desulfobacterales	28221|Deltaproteobacteria	C	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,DUF4070,Radical_SAM
k141_671_1	391619.PGA1_c33770	4.71e-64	212.0	COG4176@1|root,COG4176@2|Bacteria,1MUM4@1224|Proteobacteria,2TRF1@28211|Alphaproteobacteria,34DRJ@302485|Phaeobacter	28211|Alphaproteobacteria	U	Binding-protein-dependent transport system inner membrane component	proW	-	-	ko:K02001	ko02010,map02010	M00208	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	BPD_transp_1,DUF2628
k141_6835_1	1157708.KB907453_gene4473	2.81e-61	200.0	COG2230@1|root,COG2230@2|Bacteria,1MUW5@1224|Proteobacteria,2VI5F@28216|Betaproteobacteria,4ACT9@80864|Comamonadaceae	28216|Betaproteobacteria	M	Mycolic acid cyclopropane synthetase	-	-	2.1.1.79	ko:K00574	-	-	-	-	ko00000,ko01000	-	-	-	CMAS
k141_4987_1	498211.CJA_1374	2.64e-11	62.0	COG0640@1|root,COG0640@2|Bacteria,1N72Q@1224|Proteobacteria,1SCH5@1236|Gammaproteobacteria,1FHG3@10|Cellvibrio	1236|Gammaproteobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	ko:K22042	-	-	-	-	ko00000,ko03000	-	-	-	HTH_20,HTH_5
k141_4987_2	380394.Lferr_0210	1.52e-47	155.0	COG3439@1|root,COG3439@2|Bacteria,1RH9Z@1224|Proteobacteria,1T9P7@1236|Gammaproteobacteria,2NDUI@225057|Acidithiobacillales	225057|Acidithiobacillales	S	Domain of unknown function DUF302	-	-	-	-	-	-	-	-	-	-	-	-	DUF302
k141_61_1	1229909.NSED_09595	1.37e-139	409.0	COG0459@1|root,arCOG01257@2157|Archaea,41SDG@651137|Thaumarchaeota	651137|Thaumarchaeota	O	PFAM TCP-1 cpn60 chaperonin family	-	-	-	ko:K22447	-	-	-	-	ko00000,ko03110	-	-	-	Cpn60_TCP1
k141_5610_1	159749.K0R2H2	4.13e-16	82.8	2D443@1|root,2STT2@2759|Eukaryota	159749.K0R2H2|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_9307_1	396588.Tgr7_0351	1.28e-42	142.0	COG1146@1|root,COG1146@2|Bacteria,1R4GP@1224|Proteobacteria,1RXXW@1236|Gammaproteobacteria,1WVWW@135613|Chromatiales	135613|Chromatiales	C	reductase beta subunit	-	-	1.8.99.2	ko:K00395	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00596	R00860,R04927,R08553	RC00007,RC01239,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	-	APS-reductase_C,Fer4,Fer4_9
k141_6837_1	983545.Glaag_2764	2.02e-75	248.0	COG0495@1|root,COG0495@2|Bacteria,1MV47@1224|Proteobacteria,1RP14@1236|Gammaproteobacteria,464DK@72275|Alteromonadaceae	1236|Gammaproteobacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	iECOK1_1307.ECOK1_0652,iECS88_1305.ECS88_0684,iNRG857_1313.NRG857_02925,iPC815.YPO2610	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
k141_3751_1	310453.XP_007589306.1	3.4e-16	80.9	2CNPV@1|root,2S41B@2759|Eukaryota,38GK6@33154|Opisthokonta,3NZSP@4751|Fungi,3QM55@4890|Ascomycota,1ZYFI@147541|Dothideomycetes	4751|Fungi	S	nad dependent epimerase	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_4988_1	1121875.KB907548_gene1635	6.64e-131	390.0	COG1680@1|root,COG1680@2|Bacteria,4NI1Z@976|Bacteroidetes,1HYQF@117743|Flavobacteriia	976|Bacteroidetes	V	COG1680 Beta-lactamase class C and other penicillin binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
k141_674_1	999611.KI421504_gene366	6.89e-90	271.0	COG4177@1|root,COG4177@2|Bacteria,1PVB1@1224|Proteobacteria,2U2W8@28211|Alphaproteobacteria,28116@191028|Leisingera	28211|Alphaproteobacteria	E	Branched-chain amino acid transport system / permease component	-	-	-	ko:K01997,ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
k141_674_2	351016.RAZWK3B_08034	2.61e-06	48.1	COG0559@1|root,COG0559@2|Bacteria,1MU25@1224|Proteobacteria,2TSDS@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
k141_5612_1	1449351.RISW2_09315	3.22e-102	328.0	COG0553@1|root,COG0827@1|root,COG0553@2|Bacteria,COG0827@2|Bacteria,1MXQH@1224|Proteobacteria,2TR5V@28211|Alphaproteobacteria	28211|Alphaproteobacteria	KL	methylase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_34,Helicase_C_4,MTS
k141_2527_1	649638.Trad_2469	7.51e-10	63.9	COG3842@1|root,COG3842@2|Bacteria,1WIWM@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	P	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system	potA	-	3.6.3.31	ko:K11072	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.11.1	-	-	ABC_tran,TOBE_2
k141_2527_2	314264.ROS217_17462	6.62e-08	53.1	COG0687@1|root,COG0687@2|Bacteria,1N1BN@1224|Proteobacteria,2U2AP@28211|Alphaproteobacteria,46NI7@74030|Roseovarius	28211|Alphaproteobacteria	E	Bacterial extracellular solute-binding protein	-	-	-	ko:K11069	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	SBP_bac_8,TAT_signal
k141_8058_1	1485544.JQKP01000012_gene2124	2.84e-27	113.0	COG0001@1|root,COG0001@2|Bacteria,1MUY5@1224|Proteobacteria,2VHK9@28216|Betaproteobacteria,44V4H@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Aminotransferase class-III	hemL	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
k141_1292_1	1265313.HRUBRA_02845	9.52e-89	278.0	COG0442@1|root,COG0442@2|Bacteria,1MU7E@1224|Proteobacteria,1RN5R@1236|Gammaproteobacteria,1J4UV@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS	proS	GO:0002161,GO:0003674,GO:0003824,GO:0004812,GO:0004827,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006433,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0043906,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iUTI89_1310.UTI89_C0210	HGTP_anticodon,tRNA-synt_2b,tRNA_edit
k141_4379_1	396588.Tgr7_3057	3.06e-52	183.0	COG1022@1|root,COG1022@2|Bacteria,1MU4D@1224|Proteobacteria,1RPNE@1236|Gammaproteobacteria,1WVYG@135613|Chromatiales	135613|Chromatiales	I	PFAM AMP-dependent synthetase	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
k141_3143_1	35128.Thapsdraft1447	4.16e-41	137.0	28RUB@1|root,2QYHP@2759|Eukaryota,2XG8B@2836|Bacillariophyta	2836|Bacillariophyta	J	Binds together with S18 to 16S ribosomal RNA	rps6	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009536,GO:0019843,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0070181,GO:0097159,GO:1901363	-	-	-	-	-	-	-	-	-	-	Ribosomal_S6
k141_3143_2	35128.Thapsdraft1441	5.31e-173	489.0	COG0755@1|root,2QU0T@2759|Eukaryota,2XFBW@2836|Bacillariophyta	2836|Bacillariophyta	P	Required during biogenesis of c-type cytochromes (cytochrome c6 and cytochrome f) at the step of heme attachment	ccsA	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm
k141_8678_1	1049564.TevJSym_an00130	5.42e-45	155.0	COG2981@1|root,COG2981@2|Bacteria,1MVFT@1224|Proteobacteria,1RMQT@1236|Gammaproteobacteria,1J5RJ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	U	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway	cysZ	GO:0000096,GO:0000097,GO:0000103,GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006082,GO:0006520,GO:0006534,GO:0006790,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0008150,GO:0008152,GO:0008271,GO:0008272,GO:0008324,GO:0008509,GO:0008512,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009675,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015103,GO:0015116,GO:0015291,GO:0015293,GO:0015294,GO:0015295,GO:0015296,GO:0015318,GO:0015672,GO:0015698,GO:0016020,GO:0016021,GO:0016053,GO:0019344,GO:0019752,GO:0022804,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0034220,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044425,GO:0044459,GO:0044464,GO:0046394,GO:0051179,GO:0051234,GO:0055085,GO:0071704,GO:0071944,GO:0072348,GO:0098655,GO:0098656,GO:0098660,GO:0098661,GO:0098662,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901682,GO:1902358,GO:1902600	-	ko:K06203	-	-	-	-	ko00000	-	-	iJR904.b2413,iYL1228.KPN_02760	EI24
k141_4380_1	1298867.AUES01000066_gene4685	1.25e-36	141.0	COG1572@1|root,COG1572@2|Bacteria,1QVRG@1224|Proteobacteria	1224|Proteobacteria	G	PFAM SMP-30 Gluconolaconase	-	-	-	ko:K20952	ko05111,map05111	-	-	-	ko00000,ko00001	-	-	-	Beta-prism_lec,Calx-beta,DUF5122
k141_2529_1	688270.Celal_2387	4.82e-34	135.0	COG3210@1|root,COG3266@1|root,COG3468@1|root,COG4733@1|root,COG5644@1|root,COG3210@2|Bacteria,COG3266@2|Bacteria,COG3468@2|Bacteria,COG4733@2|Bacteria,COG5644@2|Bacteria,4PKI0@976|Bacteroidetes,1HYWF@117743|Flavobacteriia,1F9Y8@104264|Cellulophaga	976|Bacteroidetes	U	PFAM Collagen triple helix repeat (20 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Collagen
k141_8127_1	314264.ROS217_07525	1.38e-45	157.0	COG0489@1|root,COG0489@2|Bacteria,1MWQC@1224|Proteobacteria,2TXN9@28211|Alphaproteobacteria,46RPW@74030|Roseovarius	28211|Alphaproteobacteria	D	CobQ/CobB/MinD/ParA nucleotide binding domain	-	-	-	-	-	-	-	-	-	-	-	-	CbiA,ParA
k141_753_1	159749.E7BWI0	3.57e-92	270.0	COG4451@1|root,2QTPB@2759|Eukaryota	2759|Eukaryota	C	ribulose-bisphosphate carboxylase activity	rbcS	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009536,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464	4.1.1.39	ko:K01602	ko00630,ko00710,ko01100,ko01120,ko01200,map00630,map00710,map01100,map01120,map01200	M00165,M00166,M00532	R00024,R03140	RC00172,RC00859	ko00000,ko00001,ko00002,ko01000	-	-	iRC1080.CRv4_Au5_s2_g9202_t1	RbcS,RuBisCO_small
k141_753_2	35128.Thapsdraft2088	5.17e-168	480.0	COG1850@1|root,2QTI9@2759|Eukaryota,2XE5R@2836|Bacillariophyta	2836|Bacillariophyta	Q	RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process. Both reactions occur simultaneously and in competition at the same active site	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009536,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464	4.1.1.39	ko:K01601	ko00630,ko00710,ko01100,ko01120,ko01200,map00630,map00710,map01100,map01120,map01200	M00165,M00166,M00532	R00024,R03140	RC00172,RC00859	ko00000,ko00001,ko00002,ko01000	-	-	-	RuBisCO_large,RuBisCO_large_N
k141_3830_1	1288298.rosmuc_01146	2.02e-79	255.0	COG1198@1|root,COG1198@2|Bacteria,1MUUZ@1224|Proteobacteria,2TQTQ@28211|Alphaproteobacteria,46NP0@74030|Roseovarius	28211|Alphaproteobacteria	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C
k141_3830_2	1288298.rosmuc_01147	1.34e-57	189.0	COG2807@1|root,COG2807@2|Bacteria,1QV77@1224|Proteobacteria,2TT90@28211|Alphaproteobacteria,46Q2P@74030|Roseovarius	28211|Alphaproteobacteria	P	COG0477 Permeases of the major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
k141_133_2	7029.ACYPI073473-PA	4.19e-05	45.4	2EA4H@1|root,2SZ18@2759|Eukaryota,38VIS@33154|Opisthokonta,3C5X1@33208|Metazoa,3DR66@33213|Bilateria,428IV@6656|Arthropoda,3SSBM@50557|Insecta	7029.ACYPI073473-PA|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_6921_1	768671.ThimaDRAFT_1436	1.93e-83	251.0	COG0036@1|root,COG0036@2|Bacteria,1MUZM@1224|Proteobacteria,1RN3K@1236|Gammaproteobacteria,1WX9I@135613|Chromatiales	135613|Chromatiales	G	Belongs to the ribulose-phosphate 3-epimerase family	-	-	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
k141_8741_2	1380391.JIAS01000015_gene186	1.78e-39	146.0	COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,2TS19@28211|Alphaproteobacteria,2JQ7S@204441|Rhodospirillales	204441|Rhodospirillales	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	-	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_lgC,Ribonuc_red_lgN
k141_1995_1	35128.Thapsdraft1342	5.32e-69	211.0	28NVH@1|root,2QVFH@2759|Eukaryota,2XFNZ@2836|Bacillariophyta	2836|Bacillariophyta	C	Photosystem I reaction centre subunit XI	psaL	-	-	ko:K02699	ko00195,ko01100,map00195,map01100	-	-	-	ko00000,ko00001,ko00194	-	-	-	PsaL
k141_134_1	981384.AEYW01000004_gene1802	1.01e-90	286.0	COG1178@1|root,COG1178@2|Bacteria,1MXZZ@1224|Proteobacteria,2TT7F@28211|Alphaproteobacteria,4NDSA@97050|Ruegeria	28211|Alphaproteobacteria	P	Binding-protein-dependent transport system inner membrane component	fbpB	-	-	ko:K02011	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	BPD_transp_1
k141_5074_1	1121875.KB907558_gene545	4.29e-86	262.0	2CC76@1|root,3435K@2|Bacteria,4P48D@976|Bacteroidetes,1I9GK@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_8742_1	1122180.Lokhon_00501	5.12e-125	388.0	COG1674@1|root,COG1674@2|Bacteria,1MVPI@1224|Proteobacteria,2TR48@28211|Alphaproteobacteria,2P81B@245186|Loktanella	28211|Alphaproteobacteria	D	COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins	ftsK	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
k141_5684_1	1042377.AFPJ01000020_gene2040	5.89e-84	265.0	COG0405@1|root,COG0405@2|Bacteria,1MUV6@1224|Proteobacteria,1RMIT@1236|Gammaproteobacteria,465WS@72275|Alteromonadaceae	1236|Gammaproteobacteria	E	Gamma-glutamyltranspeptidase	ggt_2	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
k141_135_1	1342301.JASD01000008_gene3457	3.54e-102	313.0	COG1217@1|root,COG1217@2|Bacteria,1MV5Q@1224|Proteobacteria,2TR63@28211|Alphaproteobacteria,3ZVQ0@60136|Sulfitobacter	28211|Alphaproteobacteria	T	Elongation factor G C-terminus	typA	GO:0000027,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006996,GO:0008150,GO:0009266,GO:0009408,GO:0009409,GO:0009628,GO:0009987,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071826,GO:0071840	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2
k141_8130_1	1304883.KI912532_gene224	8.16e-50	171.0	COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,2VI01@28216|Betaproteobacteria,2KU9I@206389|Rhodocyclales	206389|Rhodocyclales	E	Aminotransferase	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
k141_5075_1	338969.Rfer_2504	1.89e-92	278.0	COG0022@1|root,COG0022@2|Bacteria,1R8KB@1224|Proteobacteria,2VKQ0@28216|Betaproteobacteria,4AD06@80864|Comamonadaceae	1224|Proteobacteria	C	Transketolase, C-terminal domain	-	-	1.2.4.1	ko:K00162,ko:K21417	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
k141_9392_1	1123237.Salmuc_00331	2.77e-95	291.0	COG4584@1|root,COG4584@2|Bacteria,1MWIV@1224|Proteobacteria,2TQKF@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	COG4584 Transposase and inactivated derivatives	istA	-	-	-	-	-	-	-	-	-	-	-	rve
k141_7498_1	439497.RR11_2293	1.02e-104	309.0	COG0039@1|root,COG0039@2|Bacteria,1MV57@1224|Proteobacteria,2TSV6@28211|Alphaproteobacteria,4NAU0@97050|Ruegeria	28211|Alphaproteobacteria	C	Catalyzes the reversible oxidation of malate to oxaloacetate	mdh	GO:0003674,GO:0003824,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0016999,GO:0017144,GO:0019752,GO:0030060,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350	1.1.1.37	ko:K00024	ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740	R00342,R07136	RC00031	ko00000,ko00001,ko00002,ko01000	-	-	-	Ldh_1_C,Ldh_1_N
k141_6924_1	977880.RALTA_B1962	2.96e-57	192.0	COG0457@1|root,COG0457@2|Bacteria,1N01S@1224|Proteobacteria,2VPBZ@28216|Betaproteobacteria,1K3AW@119060|Burkholderiaceae	28216|Betaproteobacteria	S	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_136_1	1121875.KB907547_gene3451	1.27e-91	285.0	COG5010@1|root,COG5010@2|Bacteria	2|Bacteria	-	-	M1-734	-	-	ko:K07272,ko:K20543,ko:K21007	ko02025,map02025	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01005,ko02000	1.B.55.3	-	-	SMI1_KNR4
k141_1998_1	7029.ACYPI066762-PA	3.05e-13	75.1	KOG1075@1|root,KOG1075@2759|Eukaryota	7029.ACYPI066762-PA|-	E	Ribonuclease H protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_1374_2	159749.K0T6C5	1.6e-109	379.0	COG2801@1|root,KOG0017@2759|Eukaryota,2XF4I@2836|Bacillariophyta	159749.K0T6C5|-	L	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_8744_1	1380358.JADJ01000007_gene3191	4.17e-86	271.0	COG0169@1|root,COG0408@1|root,COG0169@2|Bacteria,COG0408@2|Bacteria,1MWMF@1224|Proteobacteria,1RMM8@1236|Gammaproteobacteria,1XIDG@135619|Oceanospirillales	135619|Oceanospirillales	H	Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX	hemF	GO:0003674,GO:0005488,GO:0005515,GO:0042802,GO:0042803,GO:0046983	1.3.3.3	ko:K00228	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03220	RC00884	ko00000,ko00001,ko00002,ko01000	-	-	-	Coprogen_oxidas
k141_8131_1	1157708.KB907478_gene1212	5e-24	97.8	COG0596@1|root,COG0596@2|Bacteria,1NJ2B@1224|Proteobacteria,2W052@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
k141_8131_2	984962.XP_009547325.1	5.48e-12	69.7	COG4266@1|root,KOG4145@2759|Eukaryota,38E3W@33154|Opisthokonta,3NWKI@4751|Fungi,3UYQF@5204|Basidiomycota,224Q3@155619|Agaricomycetes,3H0TB@355688|Agaricomycetes incertae sedis	4751|Fungi	F	Allantoicase	DAL2	GO:0000050,GO:0000255,GO:0000256,GO:0003674,GO:0003824,GO:0004037,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009987,GO:0016787,GO:0016810,GO:0016813,GO:0017144,GO:0019627,GO:0034641,GO:0042737,GO:0043603,GO:0043604,GO:0043605,GO:0044237,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0046483,GO:0046700,GO:0071704,GO:0071941,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576	3.5.3.4,4.3.2.3	ko:K01477,ko:K01483	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R00776,R02422	RC00153,RC00379,RC00712	ko00000,ko00001,ko00002,ko01000	-	-	-	Allantoicase,Ureidogly_lyase
k141_7499_1	1380394.JADL01000001_gene2789	2.23e-61	206.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,2TS7G@28211|Alphaproteobacteria,2JPZX@204441|Rhodospirillales	204441|Rhodospirillales	S	COG0488 ATPase components of ABC transporters with duplicated ATPase domains	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,ABC_tran_Xtn
k141_5076_1	35128.Thapsdraft1545	2.53e-219	611.0	28ISP@1|root,2QR3X@2759|Eukaryota,2XE5P@2836|Bacillariophyta	2836|Bacillariophyta	P	One of the components of the core complex of photosystem II (PSII). It binds chlorophyll and helps catalyze the primary light-induced photochemical processes of PSII. PSII is a light- driven water plastoquinone oxidoreductase, using light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation	-	-	-	ko:K02705	ko00195,ko01100,map00195,map01100	M00161	-	-	ko00000,ko00001,ko00002,ko00194	-	-	-	PSII
k141_5687_1	1229909.NSED_08500	1.25e-141	441.0	arCOG08777@1|root,arCOG08647@2157|Archaea,41SNX@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_3218_3	545276.KB898735_gene1292	1.99e-10	61.2	COG0469@1|root,COG0469@2|Bacteria,1MU21@1224|Proteobacteria,1RMW3@1236|Gammaproteobacteria,1WXEF@135613|Chromatiales	135613|Chromatiales	G	Belongs to the pyruvate kinase family	-	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PK,PK_C
k141_5077_1	983920.Y88_2542	1.62e-103	315.0	COG0843@1|root,COG0843@2|Bacteria,1MU7S@1224|Proteobacteria,2TQP1@28211|Alphaproteobacteria,2K034@204457|Sphingomonadales	204457|Sphingomonadales	C	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B	ctaD	-	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
k141_2000_1	1122614.JHZF01000013_gene3611	1.7e-44	150.0	COG4181@1|root,COG4181@2|Bacteria,1MXG9@1224|Proteobacteria,2TS0J@28211|Alphaproteobacteria,2PCA5@252301|Oceanicola	28211|Alphaproteobacteria	Q	ATPases associated with a variety of cellular activities	ybbA	GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0008144,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
k141_2000_2	398580.Dshi_2677	6.93e-66	208.0	COG2755@1|root,COG2755@2|Bacteria,1RCXZ@1224|Proteobacteria,2U74E@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	COG2755 Lysophospholipase L1 and related esterases	tesA	-	3.1.1.5	ko:K10804	ko01040,map01040	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	Lipase_GDSL_2
k141_6926_1	595460.RRSWK_00979	3.44e-83	267.0	COG1523@1|root,COG1523@2|Bacteria,2IXJM@203682|Planctomycetes	203682|Planctomycetes	G	Belongs to the glycosyl hydrolase 13 family	-	-	3.2.1.68	ko:K01214	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R09995,R11261	-	ko00000,ko00001,ko00002,ko01000	-	CBM48,GH13	-	Alpha-amylase,CBM_48
k141_760_1	357804.Ping_2217	4.33e-18	77.4	COG0291@1|root,COG0291@2|Bacteria,1N6V4@1224|Proteobacteria,1SCHI@1236|Gammaproteobacteria,2QIDF@267894|Psychromonadaceae	1236|Gammaproteobacteria	J	Belongs to the bacterial ribosomal protein bL35 family	rpmI	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02916	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L35p
k141_1484_1	998674.ATTE01000001_gene3868	5.5e-54	191.0	COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,1RMZ8@1236|Gammaproteobacteria,460C5@72273|Thiotrichales	72273|Thiotrichales	I	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain	-	-	1.1.1.35	ko:K07516	ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212	M00087	R01975,R04737,R04739,R04741,R04743,R04745,R04748,R05305	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000	-	-	-	3HCDH,3HCDH_N,ACBP,ECH_1
k141_5186_3	159749.E7BWM0	1.5e-171	481.0	COG0090@1|root,KOG0438@2759|Eukaryota	2759|Eukaryota	J	structural constituent of ribosome	rpl2	GO:0000027,GO:0000313,GO:0000315,GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005761,GO:0005762,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009507,GO:0009526,GO:0009532,GO:0009536,GO:0009570,GO:0009941,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0031967,GO:0031974,GO:0031975,GO:0032543,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044429,GO:0044434,GO:0044435,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0065003,GO:0070013,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:0098798,GO:0140053,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02886,ko:K02965	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L2,Ribosomal_L2_C
k141_3316_1	382464.ABSI01000007_gene4090	3.35e-137	404.0	COG1274@1|root,COG1274@2|Bacteria,46UB8@74201|Verrucomicrobia,2ITQG@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle	pckG	-	4.1.1.32	ko:K01596	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko03320,ko04068,ko04151,ko04152,ko04910,ko04920,ko04922,ko04931,ko04964,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map03320,map04068,map04151,map04152,map04910,map04920,map04922,map04931,map04964	M00003	R00431,R00726	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPCK_C,PEPCK_N
k141_3944_1	1043205.AFYF01000018_gene977	5.87e-63	216.0	COG1703@1|root,COG1884@1|root,COG1703@2|Bacteria,COG1884@2|Bacteria,2GM65@201174|Actinobacteria,4FE5C@85021|Intrasporangiaceae	201174|Actinobacteria	EI	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly	icmF	GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016853,GO:0016866,GO:0019637,GO:0019693,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0043603,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0047727,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564	5.4.99.13,5.4.99.2	ko:K01848,ko:K11942	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	ArgK,B12-binding,MM_CoA_mutase
k141_869_1	7425.NV17808-PA	2.86e-16	90.1	COG2801@1|root,KOG0017@2759|Eukaryota,38DPC@33154|Opisthokonta,3BI7U@33208|Metazoa,3CTS1@33213|Bilateria,41WYJ@6656|Arthropoda,3SH01@50557|Insecta	33208|Metazoa	L	Encoded by	-	-	-	-	-	-	-	-	-	-	-	-	DUF4219,RVT_2,Retrotran_gag_2,gag_pre-integrs,rve,zf-CCHC
k141_7036_1	159749.E7BWD1	1.71e-38	147.0	COG0086@1|root,2RUNH@2759|Eukaryota,2XF5V@2836|Bacillariophyta	2836|Bacillariophyta	H	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC2	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009536,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464	-	-	-	-	-	-	-	-	-	-	RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
k141_9497_1	1234595.C725_0210	4.24e-09	60.8	COG1007@1|root,COG1007@2|Bacteria,1MV56@1224|Proteobacteria,2TQMX@28211|Alphaproteobacteria,4BPBD@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
k141_5187_1	382464.ABSI01000012_gene2004	1.02e-43	152.0	COG1595@1|root,COG1595@2|Bacteria,46VAN@74201|Verrucomicrobia,2IUN6@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
k141_6427_1	1366046.HIMB11_02415	1.24e-80	251.0	COG0683@1|root,COG0683@2|Bacteria,1PF5W@1224|Proteobacteria,2V88D@28211|Alphaproteobacteria,3ZIK4@58840|unclassified Rhodobacteraceae	28211|Alphaproteobacteria	E	Receptor family ligand binding region	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_3945_1	391008.Smal_0690	2.39e-52	176.0	COG2890@1|root,COG2890@2|Bacteria,1MXCQ@1224|Proteobacteria,1RNGK@1236|Gammaproteobacteria,1X4AP@135614|Xanthomonadales	135614|Xanthomonadales	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif	prmC	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0032259,GO:0036009,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS,Methyltransf_31
k141_2106_1	338963.Pcar_2557	1.4e-62	214.0	COG0744@1|root,COG0744@2|Bacteria,1QTST@1224|Proteobacteria,42Q00@68525|delta/epsilon subdivisions,2WJEM@28221|Deltaproteobacteria,43UHA@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Bifunctional transglycosylase second domain	mrcB	-	2.4.1.129,3.4.16.4	ko:K05365	ko00550,map00550	-	R04519	RC00005,RC00049	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase,UB2H
k141_5798_1	35128.Thapsdraft2063	2.2e-76	244.0	COG3854@1|root,2QQ4X@2759|Eukaryota,2XEFS@2836|Bacillariophyta	2836|Bacillariophyta	L	AAA domain	ycf45	-	-	-	-	-	-	-	-	-	-	-	-
k141_7601_1	748671.LCRIS_00062	0.000569	40.4	2DMNG@1|root,32SP1@2|Bacteria,1VAXC@1239|Firmicutes,4HM1Q@91061|Bacilli,3F8QG@33958|Lactobacillaceae	91061|Bacilli	S	COG NOG14552 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_2720_1	195253.Syn6312_0707	1.29e-67	221.0	COG2244@1|root,COG2244@2|Bacteria,1G2RT@1117|Cyanobacteria,1H1X8@1129|Synechococcus	1117|Cyanobacteria	S	Membrane protein involved in the export of O-antigen and teichoic acid	-	-	-	ko:K03328	-	-	-	-	ko00000	2.A.66.2	-	-	Polysacc_synt_3
k141_4576_1	96561.Dole_0194	2.11e-47	172.0	COG0243@1|root,COG0243@2|Bacteria,1NSXR@1224|Proteobacteria,43BQI@68525|delta/epsilon subdivisions	1224|Proteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	ddhA	GO:0005575,GO:0005623,GO:0042597,GO:0044464	1.17.99.2,1.7.5.1,1.8.2.4,1.8.5.3	ko:K00370,ko:K07306,ko:K10700,ko:K16964,ko:K17050	ko00642,ko00910,ko00920,ko01100,ko01120,ko01220,ko02020,map00642,map00910,map00920,map01100,map01120,map01220,map02020	M00529,M00530,M00804	R00798,R01106,R05745,R09497,R09500,R09501	RC00275,RC02555,RC02812	ko00000,ko00001,ko00002,ko01000,ko02000	5.A.3.1,5.A.3.3,5.A.3.8,5.A.3.9	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding,TAT_signal
k141_8850_1	102129.Lepto7375DRAFT_0116	1.31e-72	238.0	COG1523@1|root,COG1523@2|Bacteria,1G0PW@1117|Cyanobacteria,1H8QW@1150|Oscillatoriales	1117|Cyanobacteria	G	Belongs to the glycosyl hydrolase 13 family	-	-	3.2.1.68	ko:K01214	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R09995,R11261	-	ko00000,ko00001,ko00002,ko01000	-	CBM48,GH13	-	Alpha-amylase,CBM_48
k141_250_1	1342302.JASC01000014_gene1179	5.87e-34	119.0	COG3193@1|root,COG3193@2|Bacteria,1N08N@1224|Proteobacteria,2U5ES@28211|Alphaproteobacteria,3ZX7Y@60136|Sulfitobacter	28211|Alphaproteobacteria	S	Haem-degrading	MA20_43165	-	-	-	-	-	-	-	-	-	-	-	Haem_degrading
k141_7040_1	388401.RB2150_16142	1.66e-85	266.0	COG0651@1|root,COG0651@2|Bacteria,1QU5Z@1224|Proteobacteria,2U1B0@28211|Alphaproteobacteria	28211|Alphaproteobacteria	CP	Formate hydrogenlyase subunit 3 Multisubunit Na H antiporter, MnhD subunit	nuoL2	-	1.6.5.3	ko:K00341,ko:K05568	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000,ko02000	2.A.63.1,2.A.63.2,3.D.1	-	-	Proton_antipo_M,Proton_antipo_N
k141_7120_2	1411685.U062_00597	5.53e-19	87.4	COG1309@1|root,COG1309@2|Bacteria,1NB8F@1224|Proteobacteria,1S0YA@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	ko:K19047	-	-	-	-	ko00000,ko03000	-	-	-	TetR_N
k141_2804_1	65393.PCC7424_2802	6.51e-69	223.0	COG2403@1|root,COG2403@2|Bacteria,1G1FF@1117|Cyanobacteria,3KH0Q@43988|Cyanothece	1117|Cyanobacteria	S	cyclic 2,3-diphosphoglycerate synthetase activity	-	-	-	-	-	-	-	-	-	-	-	-	cobW
k141_3401_1	1208321.D104_18465	1.95e-10	63.2	COG1525@1|root,COG1525@2|Bacteria,1RKRQ@1224|Proteobacteria,1S7UH@1236|Gammaproteobacteria,1XM37@135619|Oceanospirillales	135619|Oceanospirillales	L	nuclease	-	-	-	-	-	-	-	-	-	-	-	-	SNase
k141_3401_2	545276.KB898727_gene509	6.32e-33	114.0	COG0254@1|root,COG0254@2|Bacteria,1MZ69@1224|Proteobacteria,1SCMH@1236|Gammaproteobacteria,1WZ1M@135613|Chromatiales	135613|Chromatiales	J	50S ribosomal protein L31	rpmE	-	-	ko:K02909	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31
k141_4036_1	292415.Tbd_1987	2.73e-48	162.0	COG1183@1|root,COG1183@2|Bacteria,1MWD9@1224|Proteobacteria,2VIME@28216|Betaproteobacteria,1KRAD@119069|Hydrogenophilales	119069|Hydrogenophilales	I	CDP-alcohol phosphatidyltransferase	-	-	2.7.8.8	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	M00093	R01800	RC00002,RC00017,RC02795	ko00000,ko00001,ko00002,ko01000	-	-	-	CDP-OH_P_transf
k141_4036_2	2340.JV46_05730	7.83e-15	73.2	COG0059@1|root,COG0059@2|Bacteria,1MV7M@1224|Proteobacteria,1RNA8@1236|Gammaproteobacteria,1J4GH@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	EH	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate	ilvC	GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004455,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0022607,GO:0036094,GO:0042802,GO:0043167,GO:0043169,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0048037,GO:0050661,GO:0050662,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0097159,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.86	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R03051,R04439,R04440,R05068,R05069,R05071	RC00726,RC00836,RC00837,RC01726	ko00000,ko00001,ko00002,ko01000	-	-	iEC042_1314.EC042_4152,iECABU_c1320.ECABU_c42560,iECED1_1282.ECED1_4460,iECO103_1326.ECO103_4390,iECO111_1330.ECO111_4600,iECO26_1355.ECO26_4812,iECP_1309.ECP_3967,iECSE_1348.ECSE_4057,iECUMN_1333.ECUMN_4300,iEcE24377_1341.EcE24377A_4285,iEcSMS35_1347.EcSMS35_4140,iJN746.PP_4678,iLF82_1304.LF82_1103	IlvC,IlvN
k141_4660_1	1229909.NSED_09040	1.61e-116	347.0	COG0004@1|root,arCOG04397@2157|Archaea,41SY0@651137|Thaumarchaeota	651137|Thaumarchaeota	P	Ammonium Transporter	-	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
k141_955_1	102129.Lepto7375DRAFT_3100	1.58e-38	132.0	COG0454@1|root,COG0456@2|Bacteria,1G8NU@1117|Cyanobacteria	1117|Cyanobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
k141_955_2	1192868.CAIU01000017_gene2376	4.76e-08	54.3	COG4143@1|root,COG4143@2|Bacteria,1MUBB@1224|Proteobacteria,2TTS4@28211|Alphaproteobacteria,43HI9@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	H	thiamine ABC transporter	tbpA	-	-	ko:K02064	ko02010,map02010	M00191	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.19	-	-	SBP_bac_1,SBP_bac_11,SBP_bac_6,SBP_bac_8
k141_7685_1	985054.JQEZ01000001_gene1953	1.08e-100	300.0	COG2801@1|root,COG2801@2|Bacteria,1MZ45@1224|Proteobacteria,2TTG7@28211|Alphaproteobacteria,4NDQZ@97050|Ruegeria	28211|Alphaproteobacteria	L	Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_29,rve,rve_3
k141_5277_1	1440774.Y900_027895	2.89e-29	120.0	COG0493@1|root,COG1144@1|root,COG0493@2|Bacteria,COG1144@2|Bacteria,2GJ0A@201174|Actinobacteria,236N6@1762|Mycobacteriaceae	201174|Actinobacteria	C	glutamate synthase	preT	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_20,Pyr_redox_2,Pyr_redox_3
k141_5889_1	1026882.MAMP_02981	1.02e-69	223.0	COG0303@1|root,COG0303@2|Bacteria,1MVD5@1224|Proteobacteria,1RMQU@1236|Gammaproteobacteria,45ZST@72273|Thiotrichales	72273|Thiotrichales	H	MoeA N-terminal region (domain I and II)	-	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MobB,MoeA_C,MoeA_N,NTP_transf_3
k141_2199_2	1250005.PHEL85_1917	1.59e-39	136.0	COG0664@1|root,COG0664@2|Bacteria,4NFIS@976|Bacteroidetes,1HXJ2@117743|Flavobacteriia,3VVUS@52959|Polaribacter	976|Bacteroidetes	K	Crp-like helix-turn-helix domain	-	-	-	ko:K01420	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
k141_956_1	682795.AciX8_1836	3.79e-12	72.0	COG4695@1|root,COG4695@2|Bacteria,3Y8AU@57723|Acidobacteria,2JN55@204432|Acidobacteriia	204432|Acidobacteriia	S	Phage portal protein	-	-	-	-	-	-	-	-	-	-	-	-	Phage_portal
k141_2806_1	1173028.ANKO01000189_gene416	1.91e-58	194.0	COG3307@1|root,COG3307@2|Bacteria,1FZV9@1117|Cyanobacteria,1HA5W@1150|Oscillatoriales	1117|Cyanobacteria	M	O-antigen ligase like membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
k141_7123_1	929562.Emtol_1650	1.75e-07	58.2	COG1572@1|root,COG1572@2|Bacteria,4NDY7@976|Bacteroidetes,47KIF@768503|Cytophagia	976|Bacteroidetes	S	Peptidase family C25	porU	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C25
k141_1575_1	1283300.ATXB01000002_gene2925	1.09e-121	369.0	COG0398@1|root,COG1249@1|root,COG0398@2|Bacteria,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,1RQTU@1236|Gammaproteobacteria,1XE1B@135618|Methylococcales	135618|Methylococcales	C	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Pyr_redox_dim,SNARE_assoc
k141_9577_1	1229909.NSED_09455	1.34e-53	181.0	COG0484@1|root,arCOG02846@2157|Archaea,41T1F@651137|Thaumarchaeota	651137|Thaumarchaeota	O	DnaJ molecular chaperone homology domain	-	-	-	-	-	-	-	-	-	-	-	-	DnaJ
k141_4037_1	35128.Thapsdraft1720	8.42e-157	457.0	COG0465@1|root,KOG0731@2759|Eukaryota,2XEEJ@2836|Bacillariophyta	2836|Bacillariophyta	O	Acts as a processive, ATP-dependent zinc metallopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	AAA,Peptidase_M41
k141_341_1	946362.XP_004988086.1	7.97e-211	594.0	COG0649@1|root,KOG2870@2759|Eukaryota,38E8K@33154|Opisthokonta	33154|Opisthokonta	C	quinone binding	NDUFS2	GO:0003674,GO:0003824,GO:0003954,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005746,GO:0005747,GO:0005759,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0006996,GO:0007005,GO:0008137,GO:0008150,GO:0008152,GO:0009055,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0010257,GO:0015980,GO:0016020,GO:0016043,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0019866,GO:0019899,GO:0022607,GO:0022900,GO:0022904,GO:0030964,GO:0031090,GO:0031625,GO:0031966,GO:0031967,GO:0031974,GO:0031975,GO:0031981,GO:0032981,GO:0032991,GO:0033108,GO:0034622,GO:0034641,GO:0042221,GO:0042493,GO:0042773,GO:0042775,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044281,GO:0044389,GO:0044422,GO:0044424,GO:0044425,GO:0044428,GO:0044429,GO:0044444,GO:0044446,GO:0044455,GO:0044464,GO:0045271,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0050896,GO:0055086,GO:0055114,GO:0065003,GO:0070013,GO:0070469,GO:0071704,GO:0071840,GO:0072521,GO:0098796,GO:0098798,GO:0098800,GO:0098803,GO:1901135,GO:1901360,GO:1901564,GO:1902494,GO:1990204	1.6.5.3,1.6.99.3	ko:K03935	ko00190,ko01100,ko04714,ko04723,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map04714,map04723,map04932,map05010,map05012,map05016	M00143	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1.6	-	-	Complex1_49kDa
k141_4662_1	1349785.BAUG01000006_gene535	4.92e-27	108.0	COG0149@1|root,COG0149@2|Bacteria,4NE2F@976|Bacteroidetes,1HY7Y@117743|Flavobacteriia	976|Bacteroidetes	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
k141_5890_1	1121912.AUHD01000005_gene1508	1.2e-76	236.0	COG0294@1|root,COG0294@2|Bacteria,4NEYJ@976|Bacteroidetes,1HXJ4@117743|Flavobacteriia	976|Bacteroidetes	H	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives	folP	-	2.5.1.15	ko:K00796	ko00790,ko01100,map00790,map01100	M00126,M00841	R03066,R03067	RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
k141_957_1	1038866.KB902792_gene3128	6.17e-10	55.8	COG2963@1|root,COG2963@2|Bacteria,1MZ3D@1224|Proteobacteria,2UBSS@28211|Alphaproteobacteria,3JZCD@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	L	Transposase	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_Tnp_1
k141_8319_1	291985.CCSI01000004_gene828	2.99e-96	310.0	COG4447@1|root,COG4447@2|Bacteria,1MVIT@1224|Proteobacteria,2VEV5@28211|Alphaproteobacteria,2K7TR@204457|Sphingomonadales	204457|Sphingomonadales	S	K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
k141_8918_1	159749.K0S1E8	1.8e-72	265.0	COG2801@1|root,KOG0017@2759|Eukaryota,2XEGG@2836|Bacillariophyta	2836|Bacillariophyta	L	transposition, RNA-mediated	-	-	-	-	-	-	-	-	-	-	-	-	RVT_2,gag_pre-integrs,rve,zf-CCHC
k141_1576_1	130081.XP_005705004.1	1.88e-104	313.0	COG0050@1|root,KOG0460@2759|Eukaryota	2759|Eukaryota	J	translation elongation factor activity	tufA	GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005634,GO:0005730,GO:0005737,GO:0009295,GO:0009507,GO:0009526,GO:0009532,GO:0009534,GO:0009535,GO:0009536,GO:0009570,GO:0009579,GO:0009941,GO:0016020,GO:0020011,GO:0031967,GO:0031974,GO:0031975,GO:0031976,GO:0031981,GO:0031984,GO:0034357,GO:0042651,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044422,GO:0044424,GO:0044428,GO:0044434,GO:0044435,GO:0044436,GO:0044444,GO:0044446,GO:0044464,GO:0048046,GO:0055035,GO:0070013	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
k141_2201_2	35128.Thapsdraft1013	4.83e-46	154.0	COG0450@1|root,KOG0852@2759|Eukaryota,2XFG5@2836|Bacillariophyta	2836|Bacillariophyta	O	Redoxin	ycf42	-	1.11.1.15	ko:K03386	ko04214,map04214	-	-	-	ko00000,ko00001,ko01000,ko04147	-	-	-	AhpC-TSA
k141_342_1	641526.ADIWIN_2258	2.89e-79	264.0	COG0308@1|root,COG1277@1|root,COG0308@2|Bacteria,COG1277@2|Bacteria,4NF3R@976|Bacteroidetes,1HXJJ@117743|Flavobacteriia	976|Bacteroidetes	E	Peptidase family M1 domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
k141_6514_1	391165.GbCGDNIH1_1036	3.53e-80	251.0	COG0766@1|root,COG0766@2|Bacteria,1MUH7@1224|Proteobacteria,2TRPH@28211|Alphaproteobacteria,2JQG0@204441|Rhodospirillales	204441|Rhodospirillales	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
k141_4039_1	983545.Glaag_3057	5.4e-21	97.1	COG1404@1|root,COG1404@2|Bacteria,1MVJE@1224|Proteobacteria,1RQ2M@1236|Gammaproteobacteria,4683H@72275|Alteromonadaceae	1236|Gammaproteobacteria	O	Peptidase inhibitor I9	-	-	-	-	-	-	-	-	-	-	-	-	Inhibitor_I9,PA,Peptidase_S8
k141_959_1	1122139.KB907862_gene677	7.05e-57	189.0	COG0055@1|root,COG0055@2|Bacteria,1MUFU@1224|Proteobacteria,1RN6U@1236|Gammaproteobacteria,1XIMC@135619|Oceanospirillales	135619|Oceanospirillales	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
k141_959_2	572477.Alvin_0047	9.56e-13	64.7	COG0355@1|root,COG0355@2|Bacteria,1RHE4@1224|Proteobacteria,1S25H@1236|Gammaproteobacteria,1WY0Q@135613|Chromatiales	135613|Chromatiales	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpC	-	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_DE,ATP-synt_DE_N
k141_5280_1	1121878.AUGL01000007_gene1270	7.64e-73	233.0	COG2224@1|root,COG2224@2|Bacteria,1MWIF@1224|Proteobacteria,1RQAK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Isocitrate lyase	aceA	-	4.1.3.1	ko:K01637	ko00630,ko01100,ko01110,ko01120,ko01200,map00630,map01100,map01110,map01120,map01200	M00012	R00479	RC00311,RC00313	ko00000,ko00001,ko00002,ko01000	-	-	-	ICL
k141_343_2	644107.SL1157_3041	2.06e-46	159.0	COG0343@1|root,COG0343@2|Bacteria,1MUCA@1224|Proteobacteria,2TR87@28211|Alphaproteobacteria,4NAYS@97050|Ruegeria	28211|Alphaproteobacteria	F	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	tgt	-	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
k141_2807_1	35128.Thapsdraft467	8.43e-153	429.0	COG1290@1|root,KOG4663@2759|Eukaryota,2XETT@2836|Bacillariophyta	2836|Bacillariophyta	C	Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions	petB	-	-	ko:K02635	ko00195,ko01100,map00195,map01100	M00162	-	-	ko00000,ko00001,ko00002,ko00194	-	-	-	Cytochrome_B
k141_2807_2	35128.Thapsdraft466	8.31e-108	311.0	COG1290@1|root,KOG4663@2759|Eukaryota,2XEDT@2836|Bacillariophyta	2836|Bacillariophyta	C	Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions	petD	-	-	ko:K02637	ko00195,ko01100,map00195,map01100	M00162	-	-	ko00000,ko00001,ko00002,ko00194	-	-	-	Cytochrom_B_C
k141_9578_2	159749.K0TQC7	3.67e-32	135.0	COG2801@1|root,KOG0017@2759|Eukaryota,2XF4I@2836|Bacillariophyta	159749.K0TQC7|-	L	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_4041_1	1229909.NSED_06440	7.03e-42	145.0	COG1454@1|root,arCOG00984@2157|Archaea,41SFC@651137|Thaumarchaeota	651137|Thaumarchaeota	C	PFAM Iron-containing alcohol dehydrogenase	-	-	-	ko:K18602	ko00720,ko01120,map00720,map01120	-	R09289	RC00087	ko00000,ko00001,ko01000	-	-	-	Fe-ADH
k141_4041_2	1229909.NSED_06435	6.34e-36	130.0	COG2141@1|root,arCOG02410@2157|Archaea,41SBM@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Luciferase-like monooxygenase	-	-	-	ko:K14728	-	-	-	-	ko00000,ko01000	-	-	-	Bac_luciferase
k141_5281_1	3880.AES92424	1.07e-10	61.2	2DSTA@1|root,2S6GN@2759|Eukaryota,37W7A@33090|Viridiplantae,3GK4J@35493|Streptophyta	35493|Streptophyta	S	Protein of unknown function (DUF2647)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2647
k141_4667_1	1430440.MGMSRv2_0647	1.43e-66	217.0	COG3039@1|root,COG3039@2|Bacteria,1MUVI@1224|Proteobacteria,2TSA7@28211|Alphaproteobacteria,2JQQ1@204441|Rhodospirillales	204441|Rhodospirillales	L	Transposase domain (DUF772)	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_6,DUF772
k141_9579_1	391603.FBALC1_08878	1.87e-127	363.0	28IZY@1|root,2Z8X8@2|Bacteria,4NKJG@976|Bacteroidetes,1I02H@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_4042_1	1121904.ARBP01000019_gene2716	1.86e-24	100.0	COG1225@1|root,COG1225@2|Bacteria,4NSHI@976|Bacteroidetes,47RHQ@768503|Cytophagia	976|Bacteroidetes	O	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
k141_6516_1	622637.KE124774_gene3742	1.08e-69	224.0	COG0137@1|root,COG0137@2|Bacteria,1MV0Y@1224|Proteobacteria,2TTGS@28211|Alphaproteobacteria,36XMZ@31993|Methylocystaceae	28211|Alphaproteobacteria	E	Arginosuccinate synthase	argG	GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Arginosuc_synth
k141_2205_1	1173024.KI912149_gene4970	6.33e-52	185.0	COG0709@1|root,COG1252@1|root,COG0709@2|Bacteria,COG1252@2|Bacteria,1G21Z@1117|Cyanobacteria,1JGXG@1189|Stigonemataceae	1117|Cyanobacteria	CE	Pyridine nucleotide-disulphide oxidoreductase	selD	-	2.7.9.3	ko:K01008	ko00450,ko01100,map00450,map01100	-	R03595	RC00002,RC02878	ko00000,ko00001,ko01000,ko03016	-	-	-	AIRS,AIRS_C,Pyr_redox_2
k141_8924_1	1469557.JSWF01000032_gene3217	1.28e-74	232.0	COG0820@1|root,COG0820@2|Bacteria,4NFH5@976|Bacteroidetes,1HY6T@117743|Flavobacteriia	976|Bacteroidetes	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Fer4_14,Radical_SAM
k141_5896_1	452659.RrIowa_0579	3.5e-16	75.5	COG0838@1|root,COG0838@2|Bacteria,1RGUT@1224|Proteobacteria,2U72Q@28211|Alphaproteobacteria,47FH2@766|Rickettsiales	766|Rickettsiales	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoA	-	1.6.5.3	ko:K00330	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q4
k141_5896_2	1238182.C882_3838	1.58e-27	110.0	COG1622@1|root,COG1622@2|Bacteria,1MWHZ@1224|Proteobacteria,2TRK6@28211|Alphaproteobacteria,2JPNT@204441|Rhodospirillales	204441|Rhodospirillales	C	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)	-	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2,COX2_TM
k141_2283_2	1054213.HMPREF9946_04155	3.58e-34	129.0	COG3004@1|root,COG3004@2|Bacteria,1MW15@1224|Proteobacteria,2TSI5@28211|Alphaproteobacteria,2JQU5@204441|Rhodospirillales	204441|Rhodospirillales	P	) H( ) antiporter that extrudes sodium in exchange for external protons	nhaA	-	-	ko:K03313	-	-	-	-	ko00000,ko02000	2.A.33.1	-	-	Na_H_antiport_1
k141_8411_1	406818.XBJ1_3918	1.48e-69	221.0	COG2826@1|root,COG2826@2|Bacteria,1MWI0@1224|Proteobacteria,1RRSE@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	IS30 family	ISPlu1B	-	-	ko:K07482	-	-	-	-	ko00000	-	-	-	HTH_38,rve
k141_8411_2	864051.BurJ1DRAFT_0114	8.56e-30	113.0	COG1943@1|root,COG1943@2|Bacteria,1MX0E@1224|Proteobacteria,2VKGR@28216|Betaproteobacteria,1KNJ7@119065|unclassified Burkholderiales	28216|Betaproteobacteria	L	Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	HTH_28,Y1_Tnp
k141_4752_2	713586.KB900536_gene1018	1.52e-101	308.0	COG0247@1|root,COG0247@2|Bacteria,1NZIG@1224|Proteobacteria,1RYPW@1236|Gammaproteobacteria,1WXQI@135613|Chromatiales	135613|Chromatiales	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_17,Fer4_8
k141_1668_2	1137281.D778_02685	6.43e-24	97.8	COG2259@1|root,COG2259@2|Bacteria,4NK73@976|Bacteroidetes,1I0YP@117743|Flavobacteriia	976|Bacteroidetes	S	Doxx family	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_7211_1	436308.Nmar_1124	1.98e-21	90.5	COG0074@1|root,arCOG01339@2157|Archaea,41SEU@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit	sucD	-	6.2.1.5	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_binding,Ligase_CoA
k141_9742_2	686340.Metal_0121	1.17e-42	147.0	COG3293@1|root,COG3385@1|root,COG3293@2|Bacteria,COG3385@2|Bacteria,1RBFK@1224|Proteobacteria,1S22S@1236|Gammaproteobacteria,1XGGK@135618|Methylococcales	135618|Methylococcales	L	PFAM Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DUF4096
k141_1752_1	6087.XP_004212749.1	7.96e-18	88.6	COG2801@1|root,KOG0017@2759|Eukaryota,38F42@33154|Opisthokonta,3BA5H@33208|Metazoa	33208|Metazoa	OU	K02A2.6-like	-	-	-	-	-	-	-	-	-	-	-	-	Asp_protease_2,RVT_1,gag-asp_proteas,rve
k141_7288_1	526225.Gobs_2965	1.2e-86	276.0	COG0508@1|root,COG1249@1|root,COG0508@2|Bacteria,COG1249@2|Bacteria,2GIXY@201174|Actinobacteria	201174|Actinobacteria	C	Dehydrogenase	lpdA_1	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Biotin_lipoyl,Pyr_redox_2,Pyr_redox_dim
k141_6683_1	767434.Fraau_0028	1.27e-55	185.0	COG0429@1|root,COG0429@2|Bacteria,1MWV1@1224|Proteobacteria,1RN39@1236|Gammaproteobacteria,1X3GG@135614|Xanthomonadales	135614|Xanthomonadales	S	hydrolase of the alpha beta-hydrolase fold	-	-	-	ko:K07019	-	-	-	-	ko00000	-	-	-	Abhydrolase_1,Abhydrolase_6,Hydrolase_4
k141_1134_1	159749.K0SPK0	2.67e-21	99.4	COG2801@1|root,2QT1S@2759|Eukaryota	2759|Eukaryota	L	transposition	-	-	-	-	-	-	-	-	-	-	-	-	RVT_1,rve
k141_5453_1	713587.THITH_01425	1.13e-36	127.0	COG1047@1|root,COG1047@2|Bacteria,1REQ1@1224|Proteobacteria,1S2MS@1236|Gammaproteobacteria,1WY6J@135613|Chromatiales	135613|Chromatiales	O	Peptidyl-prolyl cis-trans	-	-	5.2.1.8	ko:K03775	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	-
k141_5453_2	396595.TK90_0066	1.35e-67	206.0	2BK43@1|root,32EHP@2|Bacteria,1RDAC@1224|Proteobacteria,1S4CA@1236|Gammaproteobacteria,1WY9U@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_5453_3	765913.ThidrDRAFT_1496	6.41e-116	349.0	COG1053@1|root,COG1053@2|Bacteria,1NZBR@1224|Proteobacteria,1RZ0U@1236|Gammaproteobacteria,1WW7B@135613|Chromatiales	135613|Chromatiales	C	reductase, alpha subunit	-	-	1.8.99.2	ko:K00394	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00596	R00860,R04927,R08553	RC00007,RC01239,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
k141_519_1	1121104.AQXH01000001_gene1412	2.21e-42	161.0	COG0841@1|root,COG0841@2|Bacteria,4NGCI@976|Bacteroidetes	976|Bacteroidetes	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
k141_3566_1	1121937.AUHJ01000006_gene2437	2.67e-92	278.0	COG0714@1|root,COG0714@2|Bacteria,1MUFN@1224|Proteobacteria,1RN5G@1236|Gammaproteobacteria,464NM@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
k141_2372_1	1121479.AUBS01000036_gene2957	1.26e-30	114.0	COG4584@1|root,COG4584@2|Bacteria,1MWIV@1224|Proteobacteria,2TQKF@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	COG4584 Transposase and inactivated derivatives	istA	-	-	-	-	-	-	-	-	-	-	-	rve
k141_2372_2	1417296.U879_07350	1.57e-75	231.0	COG1484@1|root,COG1484@2|Bacteria,1MWQX@1224|Proteobacteria,2TRGY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	DNA replication protein	-	-	-	-	-	-	-	-	-	-	-	-	IstB_IS21
k141_520_1	501479.ACNW01000074_gene1956	2.19e-77	238.0	COG1386@1|root,COG1386@2|Bacteria,1PUA6@1224|Proteobacteria,2TU64@28211|Alphaproteobacteria	28211|Alphaproteobacteria	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves	scpB	-	-	ko:K06024	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpB
k141_5454_1	1278309.KB907100_gene1988	1.85e-113	334.0	COG0407@1|root,COG0407@2|Bacteria,1MUG1@1224|Proteobacteria,1RMDH@1236|Gammaproteobacteria,1XH3P@135619|Oceanospirillales	135619|Oceanospirillales	H	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III	hemE	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
k141_2989_1	622637.KE124774_gene3666	8.12e-64	211.0	COG5433@1|root,COG5433@2|Bacteria,1MY25@1224|Proteobacteria,2U0Y8@28211|Alphaproteobacteria,36ZP7@31993|Methylocystaceae	28211|Alphaproteobacteria	L	Transposase DDE domain group 1	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_4
k141_4225_1	1232410.KI421426_gene1329	8.28e-35	133.0	COG0744@1|root,COG0744@2|Bacteria,1RB3Z@1224|Proteobacteria,43B0J@68525|delta/epsilon subdivisions,2WN47@28221|Deltaproteobacteria,43SG0@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors	-	-	-	-	-	-	-	-	-	-	-	-	Transgly
k141_7862_1	880073.Calab_1751	1.02e-72	227.0	COG3264@1|root,COG3264@2|Bacteria,2NPZR@2323|unclassified Bacteria	2|Bacteria	M	Mechanosensitive ion channel	kefA	-	-	ko:K05802,ko:K22051	-	-	-	-	ko00000,ko02000	1.A.23.1.1,1.A.23.1.2,1.A.23.1.3	-	-	MS_channel
k141_8494_1	467661.RKLH11_1541	2.59e-22	91.3	COG1522@1|root,COG1522@2|Bacteria,1MX7R@1224|Proteobacteria,2VG6E@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	transcriptional regulator, AsnC family	-	-	-	ko:K03719	-	-	-	-	ko00000,ko03000,ko03036	-	-	-	AsnC_trans_reg,HTH_24,HTH_AsnC-type
k141_8494_2	224914.BMEII0748	1.45e-08	55.8	COG1071@1|root,COG1071@2|Bacteria,1MU5R@1224|Proteobacteria,2TSEI@28211|Alphaproteobacteria,1J21P@118882|Brucellaceae	28211|Alphaproteobacteria	C	2-oxoisovalerate dehydrogenase E1 alpha subunit N terminal	bkdA1	-	1.2.4.4	ko:K00166	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,OxoDH_E1alpha_N
k141_9089_1	211586.SO_4030	5.05e-74	246.0	COG0178@1|root,COG0178@2|Bacteria,1MW0W@1224|Proteobacteria,1RMS9@1236|Gammaproteobacteria,2Q9A7@267890|Shewanellaceae	1236|Gammaproteobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009314,GO:0009380,GO:0009381,GO:0009628,GO:0009987,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0033554,GO:0034641,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1902494,GO:1905347,GO:1905348,GO:1990391	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
k141_5455_1	367336.OM2255_05340	4.59e-70	220.0	COG4177@1|root,COG4177@2|Bacteria,1MUPI@1224|Proteobacteria,2TSID@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
k141_5455_2	593907.Celgi_3120	9.69e-08	53.1	COG1131@1|root,COG1131@2|Bacteria,2GJ0Y@201174|Actinobacteria,4F299@85016|Cellulomonadaceae	201174|Actinobacteria	V	PFAM ABC transporter related	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
k141_8495_1	105559.Nwat_0345	2.43e-74	234.0	COG4972@1|root,COG4972@2|Bacteria,1MX8P@1224|Proteobacteria,1RN8S@1236|Gammaproteobacteria,1WXGR@135613|Chromatiales	135613|Chromatiales	NU	TIGRFAM type IV pilus assembly protein PilM	-	-	-	ko:K02662	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilM_2
k141_9090_1	580332.Slit_0478	6.87e-45	164.0	COG2202@1|root,COG5001@1|root,COG2202@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,44W6J@713636|Nitrosomonadales	28216|Betaproteobacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4118,EAL,GGDEF,PAS,PAS_3,PAS_4,PAS_9,Phosphonate-bd
k141_2991_1	331869.BAL199_03109	3.1e-60	196.0	COG3181@1|root,COG3181@2|Bacteria,1PHI8@1224|Proteobacteria,2TUWU@28211|Alphaproteobacteria,4BR61@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
k141_7864_1	1187851.A33M_3194	4.79e-74	234.0	COG1024@1|root,COG1024@2|Bacteria,1QY95@1224|Proteobacteria,2U4PY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	3.7.1.21	ko:K07539	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00541	R05593,R05594,R10696	RC01430,RC01431,RC03237	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
k141_9091_1	258594.RPA0963	5.78e-94	291.0	COG0374@1|root,COG0374@2|Bacteria,1MWFJ@1224|Proteobacteria,2TSH1@28211|Alphaproteobacteria,3JR0F@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	Belongs to the NiFe NiFeSe hydrogenase large subunit family	hupL	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	1.12.99.6	ko:K06281	ko00633,ko01120,map00633,map01120	-	R08034	RC00250	ko00000,ko00001,ko01000	-	-	-	NiFeSe_Hases
k141_9744_1	106648.BBLJ01000078_gene4472	4.23e-10	67.8	COG2801@1|root,COG2801@2|Bacteria,1MVXQ@1224|Proteobacteria,1RY3S@1236|Gammaproteobacteria,3NT9C@468|Moraxellaceae	1236|Gammaproteobacteria	L	DDE domain	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve
k141_4228_1	1415754.JQMK01000002_gene1979	5.21e-11	62.0	COG0174@1|root,COG0174@2|Bacteria,1MU6V@1224|Proteobacteria,1RPNZ@1236|Gammaproteobacteria,46AV5@72275|Alteromonadaceae	1236|Gammaproteobacteria	E	Glutamine synthetase, catalytic domain	-	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C
k141_4228_2	467661.RKLH11_3608	1.07e-89	273.0	COG1454@1|root,COG1454@2|Bacteria,1MVPH@1224|Proteobacteria,2TSX8@28211|Alphaproteobacteria,3ZGT8@58840|unclassified Rhodobacteraceae	28211|Alphaproteobacteria	C	COG1454 Alcohol dehydrogenase, class IV	mdh1	-	1.1.1.1,1.1.1.61	ko:K00001,ko:K00043	ko00010,ko00071,ko00350,ko00625,ko00626,ko00650,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00010,map00071,map00350,map00625,map00626,map00650,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220	-	R00623,R00754,R01644,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	Fe-ADH
k141_2375_1	1123073.KB899241_gene2851	8.93e-77	238.0	COG0568@1|root,COG0568@2|Bacteria,1MVWR@1224|Proteobacteria,1RMFR@1236|Gammaproteobacteria,1X3U9@135614|Xanthomonadales	135614|Xanthomonadales	K	RNA polymerase sigma factor RpoH	rpoH	-	-	ko:K03089	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r4
k141_7291_1	565045.NOR51B_398	2.13e-95	295.0	COG3067@1|root,COG3067@2|Bacteria,1MV0F@1224|Proteobacteria,1RPE3@1236|Gammaproteobacteria,1J506@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	P	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons	nhaB	GO:0003674,GO:0005215,GO:0005451,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0006873,GO:0006885,GO:0008150,GO:0008324,GO:0009987,GO:0010035,GO:0010038,GO:0010226,GO:0015075,GO:0015077,GO:0015078,GO:0015081,GO:0015291,GO:0015297,GO:0015298,GO:0015299,GO:0015318,GO:0015385,GO:0015491,GO:0015672,GO:0016020,GO:0019725,GO:0022804,GO:0022857,GO:0022890,GO:0030001,GO:0030003,GO:0030004,GO:0030641,GO:0034220,GO:0035725,GO:0042221,GO:0042592,GO:0044464,GO:0045851,GO:0046873,GO:0048878,GO:0050801,GO:0050896,GO:0051179,GO:0051234,GO:0051452,GO:0051453,GO:0055067,GO:0055080,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:0098771,GO:0099516,GO:1902600	-	ko:K03314	-	-	-	-	ko00000,ko02000	2.A.34.1	-	iECP_1309.ECP_1229,iLF82_1304.LF82_1485,iNRG857_1313.NRG857_06055,iUTI89_1310.UTI89_C1372	NhaB
k141_9092_1	768066.HELO_3017	4.58e-67	212.0	COG0854@1|root,COG0854@2|Bacteria,1MU9W@1224|Proteobacteria,1RMS5@1236|Gammaproteobacteria,1XHGB@135619|Oceanospirillales	135619|Oceanospirillales	H	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate	pdxJ	-	2.6.99.2	ko:K03474	ko00750,ko01100,map00750,map01100	M00124	R05838	RC01476	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxJ
k141_3571_1	1232410.KI421418_gene2141	3.54e-63	201.0	COG2930@1|root,COG2930@2|Bacteria,1RHV6@1224|Proteobacteria,42TN0@68525|delta/epsilon subdivisions,2WQ75@28221|Deltaproteobacteria,43UN4@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Las17-binding protein actin regulator	-	-	-	-	-	-	-	-	-	-	-	-	Ysc84
k141_6068_1	314278.NB231_05746	1.95e-98	295.0	COG0517@1|root,COG0794@1|root,COG0517@2|Bacteria,COG0794@2|Bacteria,1MUXD@1224|Proteobacteria,1RMT9@1236|Gammaproteobacteria,1WWFJ@135613|Chromatiales	135613|Chromatiales	M	Arabinose 5-phosphate isomerase	-	-	5.3.1.13	ko:K06041	ko00540,ko01100,map00540,map01100	M00063	R01530	RC00541	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CBS,SIS
k141_1758_2	1123073.KB899241_gene2178	1.92e-41	147.0	COG4266@1|root,COG4266@2|Bacteria,1MXJK@1224|Proteobacteria,1RR90@1236|Gammaproteobacteria,1X9PW@135614|Xanthomonadales	135614|Xanthomonadales	F	Allantoicase repeat	-	-	3.5.3.4	ko:K01477	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R02422	RC00379,RC00712	ko00000,ko00001,ko00002,ko01000	-	-	-	Allantoicase
k141_525_1	414684.RC1_3365	4.46e-29	111.0	COG1173@1|root,COG1173@2|Bacteria,1MU26@1224|Proteobacteria,2TTEV@28211|Alphaproteobacteria,2JRED@204441|Rhodospirillales	204441|Rhodospirillales	EP	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components	-	-	-	ko:K02034,ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1,OppC_N
k141_525_2	998088.B565_1392	6.35e-31	118.0	COG0444@1|root,COG0444@2|Bacteria,1R4KB@1224|Proteobacteria,1SMBI@1236|Gammaproteobacteria,1Y55K@135624|Aeromonadales	135624|Aeromonadales	P	Belongs to the ABC transporter superfamily	oppD	-	-	ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
k141_3572_1	566466.NOR53_564	6.06e-70	226.0	COG0251@1|root,COG0667@1|root,COG0251@2|Bacteria,COG0667@2|Bacteria,1MXIU@1224|Proteobacteria,1SAUW@1236|Gammaproteobacteria,1J8U9@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	CJ	Endoribonuclease L-PSP	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red,Ribonuc_L-PSP
k141_6069_2	1121918.ARWE01000001_gene2666	1.37e-07	49.7	COG0211@1|root,COG0211@2|Bacteria,1MZGH@1224|Proteobacteria,42THK@68525|delta/epsilon subdivisions,2WQ2U@28221|Deltaproteobacteria,43SMI@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Ribosomal L27 protein	rpmA	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02899	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27
k141_526_1	570967.JMLV01000020_gene415	9.58e-109	332.0	COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,2TQJR@28211|Alphaproteobacteria,2JQA5@204441|Rhodospirillales	204441|Rhodospirillales	I	COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases	-	-	6.2.1.17	ko:K01908	ko00640,ko01100,map00640,map01100	-	R00926,R01354	RC00004,RC00043,RC00070,RC02816	ko00000,ko00001,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
k141_9094_1	1229909.NSED_06920	1.13e-78	243.0	COG0489@1|root,arCOG01846@1|root,arCOG00585@2157|Archaea,arCOG01846@2157|Archaea,41SF1@651137|Thaumarchaeota	651137|Thaumarchaeota	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	-	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	FeS_assembly_P,ParA
k141_7866_1	159749.E7BWC2	1.19e-208	594.0	COG0465@1|root,KOG0731@2759|Eukaryota,2XEEJ@2836|Bacillariophyta	2836|Bacillariophyta	O	Acts as a processive, ATP-dependent zinc metallopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	AAA,Peptidase_M41
k141_1759_1	70448.Q0P3F5	1.09e-106	331.0	COG1007@1|root,KOG4668@2759|Eukaryota,37NNE@33090|Viridiplantae,34KBF@3041|Chlorophyta	3041|Chlorophyta	C	NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus	nad5	-	1.6.5.3	ko:K03883	ko00190,ko01100,ko04714,ko04723,ko05012,map00190,map01100,map04714,map04723,map05012	M00142	R11945	RC00061	ko00000,ko00001,ko00002,ko01000,ko03029	3.D.1.6	-	-	Proton_antipo_M,Proton_antipo_N
k141_6689_1	113355.CM001775_gene3188	2.84e-31	110.0	2DNQR@1|root,32YKU@2|Bacteria,1G9K3@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_527_1	2340.JV46_07510	2.81e-58	202.0	COG1033@1|root,COG1033@2|Bacteria,1MUE1@1224|Proteobacteria,1RPIP@1236|Gammaproteobacteria,1J96Q@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	MMPL family	VP1286	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
k141_7867_1	522306.CAP2UW1_2822	2.99e-41	145.0	COG1215@1|root,COG1215@2|Bacteria,1RA75@1224|Proteobacteria,2VQQD@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
k141_6690_1	1415756.JQMY01000001_gene1371	1.52e-120	356.0	COG0165@1|root,COG0165@2|Bacteria,1MUTU@1224|Proteobacteria,2TR4H@28211|Alphaproteobacteria,2PCFM@252301|Oceanicola	28211|Alphaproteobacteria	E	Argininosuccinate lyase C-terminal	argH	GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ASL_C2,Lyase_1
k141_4232_2	1122599.AUGR01000036_gene919	2.36e-14	71.2	COG0690@1|root,COG0690@2|Bacteria,1RDI9@1224|Proteobacteria,1S3PA@1236|Gammaproteobacteria,1XKF5@135619|Oceanospirillales	135619|Oceanospirillales	U	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation	secE	-	-	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecE
k141_4844_1	1237149.C900_00918	1.83e-90	294.0	COG1197@1|root,COG1197@2|Bacteria,4NEPA@976|Bacteroidetes,47K49@768503|Cytophagia	976|Bacteroidetes	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
k141_1141_1	1229909.NSED_01150	2.41e-103	305.0	COG0673@1|root,arCOG01622@2157|Archaea,41SZ6@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	1.1.1.374	ko:K18855	-	-	-	-	ko00000,ko01000	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
k141_2380_1	1123393.KB891317_gene2441	7.05e-119	356.0	COG1053@1|root,COG1053@2|Bacteria,1NZBR@1224|Proteobacteria,2VHJ5@28216|Betaproteobacteria,1KSUD@119069|Hydrogenophilales	119069|Hydrogenophilales	C	Fumarate reductase flavoprotein C-term	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_2,Succ_DH_flav_C
k141_6149_3	1157634.KB912988_gene4378	2.47e-07	52.4	COG0451@1|root,COG0451@2|Bacteria,2I2EG@201174|Actinobacteria	201174|Actinobacteria	GM	epimerase dehydratase	-	-	4.2.1.46,5.1.3.2	ko:K01710,ko:K01784	ko00052,ko00520,ko00521,ko00523,ko00525,ko01055,ko01100,ko01130,map00052,map00520,map00521,map00523,map00525,map01055,map01100,map01130	M00361,M00362,M00632,M00793	R00291,R02984,R06513	RC00289,RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
k141_4792_1	1267535.KB906767_gene4695	8.21e-95	290.0	COG0719@1|root,COG0719@2|Bacteria,3Y2IX@57723|Acidobacteria	57723|Acidobacteria	O	Uncharacterized protein family (UPF0051)	-	-	-	ko:K09014	-	-	-	-	ko00000	-	-	-	UPF0051
k141_8452_1	983544.Lacal_0034	3.28e-68	208.0	COG0290@1|root,COG0290@2|Bacteria,4NIZ5@976|Bacteroidetes,1I178@117743|Flavobacteriia	976|Bacteroidetes	J	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins	infC	GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008	-	ko:K02520	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	IF3_C,IF3_N
k141_8452_2	391603.FBALC1_10362	3.88e-27	99.4	COG0291@1|root,COG0291@2|Bacteria,4NUVR@976|Bacteroidetes,1I52P@117743|Flavobacteriia	976|Bacteroidetes	J	Belongs to the bacterial ribosomal protein bL35 family	rpmI	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02916	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L35p
k141_9696_1	572477.Alvin_0921	2.55e-66	211.0	COG0012@1|root,COG0012@2|Bacteria,1MVM4@1224|Proteobacteria,1RMBI@1236|Gammaproteobacteria,1WWWF@135613|Chromatiales	135613|Chromatiales	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
k141_1707_1	382464.ABSI01000010_gene3896	1.08e-74	232.0	COG2801@1|root,COG2801@2|Bacteria,46VBX@74201|Verrucomicrobia,2IUPH@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	Homeodomain-like domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_32,rve
k141_1082_1	1229909.NSED_00560	3.01e-144	411.0	COG0109@1|root,arCOG00479@2157|Archaea,41SFH@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group	-	-	2.5.1.141	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	M00154	R07411	RC01786	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	-	-	-	UbiA
k141_7812_1	1137799.GZ78_22295	8.25e-95	286.0	COG0356@1|root,COG0356@2|Bacteria,1MV87@1224|Proteobacteria,1RPHK@1236|Gammaproteobacteria,1XH68@135619|Oceanospirillales	135619|Oceanospirillales	C	it plays a direct role in the translocation of protons across the membrane	atpB	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
k141_6638_1	443144.GM21_4047	1.99e-81	252.0	COG3547@1|root,COG3547@2|Bacteria,1MXKJ@1224|Proteobacteria,42RYH@68525|delta/epsilon subdivisions,2WNT0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	PFAM transposase IS116 IS110 IS902 family	-	-	-	ko:K07486	-	-	-	-	ko00000	-	-	-	DEDD_Tnp_IS110,Transposase_20
k141_5405_1	349521.HCH_06449	3.81e-66	224.0	COG3127@1|root,COG3127@2|Bacteria,1MU9R@1224|Proteobacteria,1RM8Y@1236|Gammaproteobacteria,1XHVX@135619|Oceanospirillales	135619|Oceanospirillales	Q	ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	-
k141_3519_1	1484460.JSWG01000003_gene757	3.47e-84	254.0	COG3279@1|root,COG3279@2|Bacteria,4NPHA@976|Bacteroidetes,1IIN4@117743|Flavobacteriia	976|Bacteroidetes	T	LytTr DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
k141_3519_2	1123278.KB893581_gene974	0.000212	44.3	COG2972@1|root,COG2972@2|Bacteria,4NH51@976|Bacteroidetes,47MBJ@768503|Cytophagia	976|Bacteroidetes	T	regulator of cell autolysis	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_5,His_kinase
k141_2325_1	331869.BAL199_11087	8.68e-58	190.0	COG1158@1|root,COG1158@2|Bacteria,1MUCF@1224|Proteobacteria,2TRB4@28211|Alphaproteobacteria,4BP7U@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
k141_8456_1	1235803.C825_00029	7.43e-18	87.0	COG1893@1|root,COG1893@2|Bacteria,4NMFF@976|Bacteroidetes,2FNZU@200643|Bacteroidia,22XU7@171551|Porphyromonadaceae	976|Bacteroidetes	H	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid	panE	-	1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000	-	-	-	ApbA,ApbA_C
k141_6640_1	1485544.JQKP01000012_gene2151	1.66e-06	49.3	COG0339@1|root,COG0339@2|Bacteria,1MU1K@1224|Proteobacteria,2VHPQ@28216|Betaproteobacteria,44VER@713636|Nitrosomonadales	28216|Betaproteobacteria	E	PFAM peptidase M3A and M3B thimet oligopeptidase F	prlC	-	3.4.24.70	ko:K01414	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3
k141_6640_2	51511.ENSCSAVP00000007785	1.12e-35	134.0	COG1249@1|root,KOG0405@2759|Eukaryota,39J8D@33154|Opisthokonta,3BDB0@33208|Metazoa,3D06N@33213|Bilateria,482J2@7711|Chordata	33208|Metazoa	Q	glutathione-disulfide reductase activity	GSR	GO:0000003,GO:0000166,GO:0000302,GO:0000303,GO:0000305,GO:0002931,GO:0003674,GO:0003824,GO:0004362,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005829,GO:0005886,GO:0006091,GO:0006139,GO:0006518,GO:0006575,GO:0006725,GO:0006749,GO:0006790,GO:0006807,GO:0006950,GO:0006979,GO:0007276,GO:0007283,GO:0007568,GO:0007584,GO:0008150,GO:0008152,GO:0009055,GO:0009605,GO:0009636,GO:0009897,GO:0009986,GO:0009987,GO:0009991,GO:0010033,GO:0010035,GO:0010038,GO:0010039,GO:0010041,GO:0014823,GO:0015036,GO:0015037,GO:0015038,GO:0015949,GO:0016020,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0018996,GO:0019953,GO:0022404,GO:0022414,GO:0022900,GO:0031667,GO:0031974,GO:0032501,GO:0032502,GO:0032504,GO:0033189,GO:0033218,GO:0033273,GO:0033554,GO:0033993,GO:0034599,GO:0034641,GO:0035094,GO:0036094,GO:0042221,GO:0042277,GO:0042303,GO:0042395,GO:0042493,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043295,GO:0043603,GO:0044237,GO:0044238,GO:0044281,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044444,GO:0044446,GO:0044459,GO:0044464,GO:0044703,GO:0045471,GO:0046483,GO:0046677,GO:0046686,GO:0046983,GO:0048037,GO:0048232,GO:0048609,GO:0050660,GO:0050661,GO:0050662,GO:0050896,GO:0051186,GO:0051704,GO:0051716,GO:0055086,GO:0055114,GO:0070013,GO:0070887,GO:0071704,GO:0071944,GO:0072341,GO:0097159,GO:0097237,GO:0097305,GO:0098552,GO:0098622,GO:0098754,GO:0098869,GO:1900750,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901681,GO:1901700,GO:1990748	1.8.1.7	ko:K00383	ko00480,ko04918,map00480,map04918	-	R00094,R00115	RC00011	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,Pyr_redox_dim
k141_6012_2	1123247.AUIJ01000009_gene3062	1.27e-48	171.0	COG0021@1|root,COG0021@2|Bacteria,1MUEY@1224|Proteobacteria,2TQUX@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate	tktA	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
k141_9045_1	1335757.SPICUR_09150	5.8e-08	55.8	COG0677@1|root,COG0677@2|Bacteria,1MUC6@1224|Proteobacteria,1RMX0@1236|Gammaproteobacteria,1WW96@135613|Chromatiales	135613|Chromatiales	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	-	-	-	ko:K02474	ko00520,map00520	-	R06894	RC00291	ko00000,ko00001,ko01000,ko01005	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
k141_5407_1	1035308.AQYY01000002_gene505	2.32e-05	50.1	COG1752@1|root,COG1752@2|Bacteria,1UUVB@1239|Firmicutes,24HQS@186801|Clostridia,262JF@186807|Peptococcaceae	186801|Clostridia	T	esterase of the alpha-beta hydrolase	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
k141_5407_2	247634.GPB2148_462	8.89e-11	62.4	COG3119@1|root,COG3119@2|Bacteria,1MUJH@1224|Proteobacteria,1RN2V@1236|Gammaproteobacteria,1J88Q@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	P	COG3119 Arylsulfatase A and related enzymes	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase,Sulfatase_C
k141_3521_1	70448.Q0P3F5	4.91e-85	270.0	COG1007@1|root,KOG4668@2759|Eukaryota,37NNE@33090|Viridiplantae,34KBF@3041|Chlorophyta	3041|Chlorophyta	C	NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus	nad5	-	1.6.5.3	ko:K03883	ko00190,ko01100,ko04714,ko04723,ko05012,map00190,map01100,map04714,map04723,map05012	M00142	R11945	RC00061	ko00000,ko00001,ko00002,ko01000,ko03029	3.D.1.6	-	-	Proton_antipo_M,Proton_antipo_N
k141_1087_1	357804.Ping_2510	1.13e-69	218.0	COG0395@1|root,COG0395@2|Bacteria,1MUWS@1224|Proteobacteria,1T9YD@1236|Gammaproteobacteria,2QJ3T@267894|Psychromonadaceae	1236|Gammaproteobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
k141_6013_1	1499967.BAYZ01000013_gene6421	9.1e-26	109.0	COG1012@1|root,COG1012@2|Bacteria,2NQI9@2323|unclassified Bacteria	2|Bacteria	C	Aldehyde dehydrogenase family	eutE	GO:0003674,GO:0003824,GO:0004029,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114	1.2.1.87	ko:K04021,ko:K13922	ko00620,ko00640,ko01100,ko01120,map00620,map00640,map01100,map01120	-	R00228,R09097	RC00004,RC00184,RC01195	ko00000,ko00001,ko01000	-	-	-	Aldedh
k141_6013_2	398578.Daci_3673	0.000709	42.0	COG1804@1|root,COG1804@2|Bacteria,1MVY1@1224|Proteobacteria,2VKB0@28216|Betaproteobacteria,4ACU4@80864|Comamonadaceae	28216|Betaproteobacteria	C	PFAM L-carnitine dehydratase bile acid-inducible protein F	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
k141_6641_1	948106.AWZT01000016_gene202	5.88e-128	376.0	COG1140@1|root,COG1140@2|Bacteria,1MW9Q@1224|Proteobacteria,2VJ1V@28216|Betaproteobacteria,1K0UD@119060|Burkholderiaceae	28216|Betaproteobacteria	C	nitrate reductase beta subunit	narH	-	1.7.5.1	ko:K00371,ko:K17051	ko00910,ko01120,ko02020,map00910,map01120,map02020	M00529,M00530,M00804	R00798,R01106,R09497	RC02812	ko00000,ko00001,ko00002,ko01000,ko02000	5.A.3.1,5.A.3.8	-	-	Fer4_11,Nitr_red_bet_C
k141_8457_1	266835.14027468	1.11e-21	93.2	COG3293@1|root,COG3293@2|Bacteria,1P5HD@1224|Proteobacteria,2TUQI@28211|Alphaproteobacteria,43M7H@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	L	Transposase DDE domain	-	-	-	ko:K07492	-	-	-	-	ko00000	-	-	-	DDE_Tnp_1,DDE_Tnp_1_2,DUF4096
k141_8457_2	627192.SLG_18330	1.68e-51	165.0	COG0309@1|root,COG0309@2|Bacteria,1RDJ4@1224|Proteobacteria,2U7HE@28211|Alphaproteobacteria,2K3ZP@204457|Sphingomonadales	204457|Sphingomonadales	O	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_2,DUF4096
k141_6642_1	1211115.ALIQ01000206_gene4729	2.7e-41	145.0	COG2084@1|root,COG2084@2|Bacteria,1MUGU@1224|Proteobacteria,2TT50@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases	glxR	-	1.1.1.60	ko:K00042	ko00630,ko01100,map00630,map01100	-	R01745,R01747	RC00099	ko00000,ko00001,ko01000	-	-	-	NAD_binding_11,NAD_binding_2
k141_6105_1	1211777.BN77_0686	7.11e-71	224.0	COG4143@1|root,COG4143@2|Bacteria,1MUBB@1224|Proteobacteria,2TTS4@28211|Alphaproteobacteria,4B8QF@82115|Rhizobiaceae	28211|Alphaproteobacteria	H	ABC-type thiamine transport system, periplasmic component	tbpA	-	-	ko:K02064	ko02010,map02010	M00191	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.19	-	-	SBP_bac_1,SBP_bac_11,SBP_bac_6,SBP_bac_8
k141_4263_1	143224.JQMD01000002_gene174	8.38e-06	52.8	COG3940@1|root,COG3940@2|Bacteria,4NQXR@976|Bacteroidetes	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 43 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_43
k141_3605_1	391008.Smal_2621	5.55e-63	202.0	COG1131@1|root,COG1131@2|Bacteria,1R3XF@1224|Proteobacteria,1S0MM@1236|Gammaproteobacteria,1X3B4@135614|Xanthomonadales	135614|Xanthomonadales	V	abc transporter atp-binding protein	nodI	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
k141_7328_1	1123073.KB899241_gene3025	1.77e-25	96.3	COG4391@1|root,COG4391@2|Bacteria,1N7QM@1224|Proteobacteria,1SHHF@1236|Gammaproteobacteria,1X821@135614|Xanthomonadales	135614|Xanthomonadales	S	protein conserved in bacteria	VL23_05015	-	-	-	-	-	-	-	-	-	-	-	zf-CHCC
k141_556_1	998088.B565_0493	2.54e-119	357.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,1RQ36@1236|Gammaproteobacteria,1Y3TY@135624|Aeromonadales	135624|Aeromonadales	L	Belongs to the DEAD box helicase family	-	-	3.6.4.13	ko:K05591	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	DEAD,DbpA,Helicase_C
k141_5492_1	293826.Amet_3897	7.38e-19	87.8	COG3415@1|root,COG3415@2|Bacteria,1U5WP@1239|Firmicutes,24RC3@186801|Clostridia	186801|Clostridia	L	Homeodomain-like domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_32
k141_5492_2	1123278.KB893449_gene1160	1.2e-15	73.6	COG3415@1|root,COG3415@2|Bacteria	2|Bacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	HTH_32
k141_7897_1	234267.Acid_5112	3.54e-75	236.0	COG0092@1|root,COG0092@2|Bacteria,3Y3ZN@57723|Acidobacteria	57723|Acidobacteria	J	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation	rpsC	-	-	ko:K02982	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KH_2,Ribosomal_S3_C
k141_3606_1	977880.RALTA_A1001	1.77e-16	79.3	COG4630@1|root,COG4630@2|Bacteria,1MWI1@1224|Proteobacteria,2VI0J@28216|Betaproteobacteria,1K1BZ@119060|Burkholderiaceae	28216|Betaproteobacteria	C	Xanthine dehydrogenase small subunit	xdhA	-	1.17.1.4	ko:K13481	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103	RC00143	ko00000,ko00001,ko00002,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5,Fer2,Fer2_2
k141_3606_2	1232683.ADIMK_3963	1.29e-07	52.4	COG3845@1|root,COG3845@2|Bacteria,1NT0H@1224|Proteobacteria,1T1GV@1236|Gammaproteobacteria,46D9T@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	ATPases associated with a variety of cellular activities	-	-	3.6.3.17	ko:K02056	-	M00221	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.2	-	-	ABC_tran
k141_8539_1	331869.BAL199_27975	5.98e-37	138.0	COG2807@1|root,COG2807@2|Bacteria,1QUCZ@1224|Proteobacteria,2TY3D@28211|Alphaproteobacteria,4BTDY@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	P	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
k141_7329_1	159749.E7BWH1	1.09e-131	385.0	28JG1@1|root,2QRV6@2759|Eukaryota,2XEM0@2836|Bacillariophyta	2836|Bacillariophyta	P	One of the components of the core complex of photosystem II (PSII). It binds chlorophyll and helps catalyze the primary light-induced photochemical processes of PSII. PSII is a light- driven water plastoquinone oxidoreductase, using light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation	psbB	-	-	ko:K02704	ko00195,ko01100,map00195,map01100	M00161	-	-	ko00000,ko00001,ko00002,ko00194	-	-	-	PSII
k141_1793_1	754477.Q7C_2373	1.21e-66	219.0	COG0661@1|root,COG0661@2|Bacteria,1MU1Z@1224|Proteobacteria,1RNQM@1236|Gammaproteobacteria,45ZT8@72273|Thiotrichales	72273|Thiotrichales	S	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis	ubiB	-	-	ko:K03688	-	-	-	-	ko00000	-	-	-	ABC1
k141_6107_1	331869.BAL199_20875	4.48e-55	180.0	COG4176@1|root,COG4176@2|Bacteria,1QTTE@1224|Proteobacteria,2TS3U@28211|Alphaproteobacteria,4BPF1@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	P	Binding-protein-dependent transport system inner membrane component	choW	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006836,GO:0008150,GO:0015695,GO:0015696,GO:0015871,GO:0016020,GO:0044464,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944	-	ko:K02001	ko02010,map02010	M00208	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	BPD_transp_1
k141_6107_2	314271.RB2654_08682	8.75e-11	62.4	COG4175@1|root,COG4175@2|Bacteria,1MU86@1224|Proteobacteria,2TS8Y@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	COG4175 ABC-type proline glycine betaine transport system ATPase component	choV	-	3.6.3.32	ko:K02000	ko02010,map02010	M00208	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.12	-	-	ABC_tran
k141_7898_1	391624.OIHEL45_20126	3.65e-99	297.0	COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,2TQMR@28211|Alphaproteobacteria	28211|Alphaproteobacteria	V	ABC-type multidrug transport system ATPase and permease	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
k141_4265_1	1217720.ALOX01000101_gene874	6.91e-101	302.0	COG0109@1|root,COG0109@2|Bacteria,1MW3S@1224|Proteobacteria,2TRD8@28211|Alphaproteobacteria,2JPAB@204441|Rhodospirillales	204441|Rhodospirillales	O	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group	ctaB	-	2.5.1.141	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	M00154	R07411	RC01786	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	-	-	-	UbiA
k141_5494_1	1232437.KL662016_gene1174	2.79e-83	251.0	COG3328@1|root,COG3328@2|Bacteria,1MU4P@1224|Proteobacteria,43AA7@68525|delta/epsilon subdivisions,2X2GR@28221|Deltaproteobacteria,2MPBD@213118|Desulfobacterales	28221|Deltaproteobacteria	L	MULE transposase domain	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_mut
k141_4875_1	349124.Hhal_1005	6.17e-120	350.0	COG1077@1|root,COG1077@2|Bacteria,1MUMW@1224|Proteobacteria,1RN82@1236|Gammaproteobacteria,1WW91@135613|Chromatiales	135613|Chromatiales	D	TIGRFAM Cell shape determining protein MreB Mrl	-	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
k141_1794_1	338966.Ppro_1841	3.7e-38	136.0	COG2801@1|root,COG2801@2|Bacteria,1PBHA@1224|Proteobacteria	1224|Proteobacteria	L	Transposase and inactivated derivatives	-	-	2.7.7.49	ko:K00986,ko:K07497	-	-	-	-	ko00000,ko01000	-	-	-	HTH_32,rve,rve_3
k141_558_2	1137281.D778_00449	6.85e-108	316.0	COG0157@1|root,COG0157@2|Bacteria,4NDXF@976|Bacteroidetes,1HXPC@117743|Flavobacteriia	976|Bacteroidetes	H	Belongs to the NadC ModD family	nadC	-	2.4.2.19	ko:K00767	ko00760,ko01100,map00760,map01100	M00115	R03348	RC02877	ko00000,ko00001,ko00002,ko01000	-	-	-	QRPTase_C,QRPTase_N
k141_7331_1	713586.KB900536_gene2156	1.68e-08	53.1	COG1832@1|root,COG1832@2|Bacteria	2|Bacteria	S	CoA binding domain	-	-	-	ko:K06929	-	-	-	-	ko00000	-	-	-	CoA_binding_2
k141_7331_2	697282.Mettu_1568	2.69e-40	139.0	COG1495@1|root,COG1495@2|Bacteria,1RIJE@1224|Proteobacteria,1S6WD@1236|Gammaproteobacteria,1XEYA@135618|Methylococcales	135618|Methylococcales	O	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein	dsbB	-	-	ko:K03611	-	-	-	-	ko00000,ko03110	5.A.2.1	-	-	DsbB
k141_559_1	1317118.ATO8_21461	5.85e-27	107.0	COG3547@1|root,COG3547@2|Bacteria,1MUER@1224|Proteobacteria,2TQTP@28211|Alphaproteobacteria,4KNPA@93682|Roseivivax	28211|Alphaproteobacteria	L	Transposase IS116/IS110/IS902 family	-	-	-	ko:K07486	-	-	-	-	ko00000	-	-	-	DEDD_Tnp_IS110,Transposase_20
k141_4877_1	87626.PTD2_19992	5.36e-76	243.0	COG0659@1|root,COG0659@2|Bacteria,1MVWV@1224|Proteobacteria,1RMCN@1236|Gammaproteobacteria,2PZVA@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	P	COG0659 Sulfate permease and related transporters (MFS superfamily)	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,STAS_2,Sulfate_transp
k141_8541_1	766499.C357_13917	2.6e-98	290.0	COG1845@1|root,COG1845@2|Bacteria,1MUCK@1224|Proteobacteria,2TQWA@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	heme copper-type cytochrome quinol oxidase, subunit 3	ctaE	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	1.9.3.1	ko:K02276	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.6	-	-	COX3
k141_6725_1	159749.E7BWC5	3.4e-234	646.0	COG1239@1|root,2QRUY@2759|Eukaryota,2XEQ7@2836|Bacillariophyta	2836|Bacillariophyta	Q	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX	-	-	-	-	-	-	-	-	-	-	-	-	Mg_chelatase
k141_2416_2	1327990.S0A059_9CAUD	1.56e-10	61.6	4QAIK@10239|Viruses,4QUPH@35237|dsDNA viruses  no RNA stage,4QPEB@28883|Caudovirales,4QNC3@10744|Podoviridae	10744|Podoviridae	S	endonuclease activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_560_1	1288298.rosmuc_03285	3.43e-93	279.0	COG0686@1|root,COG0686@2|Bacteria,1MXDG@1224|Proteobacteria,2TSFN@28211|Alphaproteobacteria,46PNW@74030|Roseovarius	28211|Alphaproteobacteria	C	Saccharopine dehydrogenase	sdh	-	1.5.1.7	ko:K00290	ko00300,ko00310,ko01100,ko01110,ko01130,ko01230,map00300,map00310,map01100,map01110,map01130,map01230	M00030,M00032	R00715	RC00217,RC01532	ko00000,ko00001,ko00002,ko01000	-	-	-	AlaDh_PNT_N
k141_4268_1	391593.RCCS2_05694	3.07e-71	222.0	COG0697@1|root,COG0697@2|Bacteria,1MXJ6@1224|Proteobacteria,2U5CF@28211|Alphaproteobacteria,2P2BX@2433|Roseobacter	28211|Alphaproteobacteria	EG	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily	-	-	-	-	-	-	-	-	-	-	-	-	EamA
k141_9131_1	1223410.KN050846_gene2613	3.2e-30	116.0	COG1663@1|root,COG1663@2|Bacteria,4NE2I@976|Bacteroidetes,1HWU8@117743|Flavobacteriia	976|Bacteroidetes	M	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA)	lpxK	-	2.7.1.130	ko:K00912	ko00540,ko01100,map00540,map01100	M00060	R04657	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	LpxK
k141_9131_2	1484460.JSWG01000012_gene1444	3.59e-34	130.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,4NDXU@976|Bacteroidetes,1HYZK@117743|Flavobacteriia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg,TPR_12,TPR_8
k141_7901_1	991905.SL003B_1051	1.14e-79	254.0	COG0028@1|root,COG0028@2|Bacteria,1MX3Q@1224|Proteobacteria,2U2RW@28211|Alphaproteobacteria	28211|Alphaproteobacteria	EH	Belongs to the TPP enzyme family	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
k141_3029_1	71139.XP_010026635.1	1.86e-28	132.0	COG2801@1|root,KOG0017@2759|Eukaryota,37RIF@33090|Viridiplantae,3GHHW@35493|Streptophyta	35493|Streptophyta	L	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	RVT_2,Retrotran_gag_3
k141_6111_1	765910.MARPU_11200	8.22e-85	263.0	COG1073@1|root,COG1765@1|root,COG1073@2|Bacteria,COG1765@2|Bacteria,1N2BT@1224|Proteobacteria,1RMZV@1236|Gammaproteobacteria,1X2SU@135613|Chromatiales	135613|Chromatiales	O	OsmC-like protein	-	-	-	ko:K06889,ko:K07397	-	-	-	-	ko00000	-	-	-	Hydrolase_4,OsmC
k141_7333_1	1286106.MPL1_05884	1.13e-111	340.0	COG0326@1|root,COG0326@2|Bacteria,1MUUE@1224|Proteobacteria,1RNWD@1236|Gammaproteobacteria,4600N@72273|Thiotrichales	72273|Thiotrichales	O	Molecular chaperone. Has ATPase activity	htpG	-	-	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	-	-	-	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	-	-	-	HATPase_c,HATPase_c_3,HSP90
k141_4878_1	998674.ATTE01000001_gene2279	5.86e-128	380.0	COG2759@1|root,COG2759@2|Bacteria,1MUR8@1224|Proteobacteria,1RME6@1236|Gammaproteobacteria,46012@72273|Thiotrichales	72273|Thiotrichales	F	Belongs to the formate--tetrahydrofolate ligase family	fhs	-	6.3.4.3	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R00943	RC00026,RC00111	ko00000,ko00001,ko00002,ko01000	-	-	-	FTHFS
k141_6727_1	1231392.OCGS_0177	2.92e-21	97.1	COG0863@1|root,COG1475@1|root,COG0863@2|Bacteria,COG1475@2|Bacteria,1MVH7@1224|Proteobacteria,2TRNA@28211|Alphaproteobacteria	28211|Alphaproteobacteria	KL	Belongs to the N(4) N(6)-methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	N6_N4_Mtase,ParBc
k141_9315_2	244582.JQAK01000022_gene652	1.89e-33	120.0	2DNPH@1|root,32YF1@2|Bacteria,1NARM@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_680_1	317013.NY99_09640	2.37e-39	149.0	COG2352@1|root,COG2352@2|Bacteria,1MUD5@1224|Proteobacteria,1RPTP@1236|Gammaproteobacteria,1X4MI@135614|Xanthomonadales	135614|Xanthomonadales	C	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle	ppc	GO:0003674,GO:0003824,GO:0004611,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008964,GO:0016829,GO:0016830,GO:0016831,GO:0044424,GO:0044444,GO:0044464	4.1.1.31	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	M00168,M00170,M00171,M00172,M00173,M00346,M00374	R00345	RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPcase
k141_2533_1	1415778.JQMM01000001_gene152	1.17e-60	207.0	COG0210@1|root,COG0210@2|Bacteria,1MU0G@1224|Proteobacteria,1RNJI@1236|Gammaproteobacteria,1J4ZV@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	L	it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction	rep	GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006725,GO:0006807,GO:0006996,GO:0007049,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022402,GO:0032392,GO:0032508,GO:0034641,GO:0034645,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044786,GO:0044787,GO:0046483,GO:0050896,GO:0051276,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576	3.6.4.12	ko:K03656,ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
k141_1918_1	583355.Caka_2992	1.48e-101	305.0	COG0126@1|root,COG0126@2|Bacteria,46SI9@74201|Verrucomicrobia,3K76C@414999|Opitutae	414999|Opitutae	G	Phosphoglycerate kinase	pgk	-	2.7.2.3	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01512	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
k141_6842_1	6334.EFV62422	9.52e-22	102.0	COG2801@1|root,KOG0017@2759|Eukaryota,38VHA@33154|Opisthokonta,3C3G8@33208|Metazoa,3DK75@33213|Bilateria	33208|Metazoa	L	gag-polypeptide of LTR copia-type	-	-	-	-	-	-	-	-	-	-	-	-	DUF4219,Retrotran_gag_2
k141_3760_1	35128.Thapsdraft1611	9.43e-56	190.0	28JJ8@1|root,2QRYE@2759|Eukaryota,2XEB4@2836|Bacillariophyta	2836|Bacillariophyta	C	PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX. PSI is a plastocyanin cytochrome c6-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn. Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin or cytochrome c6	psaB	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009534,GO:0009535,GO:0009536,GO:0009579,GO:0016020,GO:0016168,GO:0031976,GO:0031984,GO:0034357,GO:0042651,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044436,GO:0044444,GO:0044446,GO:0044464,GO:0046906,GO:0048037,GO:0055035,GO:0097159,GO:1901363	-	ko:K02690	ko00195,ko01100,map00195,map01100	M00163	-	-	ko00000,ko00001,ko00002,ko00194	-	-	-	PsaA_PsaB
k141_4384_1	35128.Thapsdraft1611	3.06e-256	717.0	28JJ8@1|root,2QRYE@2759|Eukaryota,2XEB4@2836|Bacillariophyta	2836|Bacillariophyta	C	PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX. PSI is a plastocyanin cytochrome c6-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn. Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin or cytochrome c6	psaB	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009534,GO:0009535,GO:0009536,GO:0009579,GO:0016020,GO:0016168,GO:0031976,GO:0031984,GO:0034357,GO:0042651,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044436,GO:0044444,GO:0044446,GO:0044464,GO:0046906,GO:0048037,GO:0055035,GO:0097159,GO:1901363	-	ko:K02690	ko00195,ko01100,map00195,map01100	M00163	-	-	ko00000,ko00001,ko00002,ko00194	-	-	-	PsaA_PsaB
k141_7444_1	666509.RCA23_c12630	1.67e-83	249.0	COG2801@1|root,COG2801@2|Bacteria,1MVN5@1224|Proteobacteria,2TQK0@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	COG2801 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	HTH_21,rve_3
k141_9316_1	297246.lpp2759	5.67e-67	215.0	COG1290@1|root,COG1290@2|Bacteria,1MV97@1224|Proteobacteria,1RNCP@1236|Gammaproteobacteria,1JDGW@118969|Legionellales	118969|Legionellales	C	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis	petB	-	-	ko:K00412	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002,ko03029	-	-	-	Cytochrom_B_C,Cytochrome_B
k141_9316_2	1123228.AUIH01000067_gene2147	1.33e-06	51.6	COG1290@1|root,COG1290@2|Bacteria,1MV97@1224|Proteobacteria,1RNCP@1236|Gammaproteobacteria,1XHEG@135619|Oceanospirillales	135619|Oceanospirillales	C	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis	petB	-	-	ko:K00412	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002,ko03029	-	-	-	Cytochrom_B_C,Cytochrome_B
k141_681_1	1131269.AQVV01000014_gene210	3.56e-59	206.0	COG2844@1|root,COG2844@2|Bacteria	2|Bacteria	O	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen	glnD	-	1.1.1.3,1.4.1.2,2.7.7.19,2.7.7.42,2.7.7.59,2.7.7.72,2.7.7.89	ko:K00003,ko:K00970,ko:K00974,ko:K00982,ko:K00990,ko:K06950,ko:K15371	ko00220,ko00250,ko00260,ko00270,ko00300,ko00430,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,ko02020,ko03013,ko03018,map00220,map00250,map00260,map00270,map00300,map00430,map00910,map01100,map01110,map01120,map01130,map01230,map02020,map03013,map03018	M00017,M00018	R00243,R01773,R01775,R09382,R09383,R09384,R09386	RC00006,RC00078,RC00087,RC02799	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	ACT,GlnD_UR_UTase,HD,NTP_transf_2,PolyA_pol,PolyA_pol_RNAbd
k141_1301_1	1288298.rosmuc_02132	1.26e-84	263.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,2TR2W@28211|Alphaproteobacteria,46PKH@74030|Roseovarius	28211|Alphaproteobacteria	IQ	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II	-	-	-	ko:K18661	ko00280,map00280	-	R03383	RC00004,RC00137	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C
k141_5618_2	35128.Thapsdraft2028	2.49e-15	70.5	2CHHR@1|root,2T9WD@2759|Eukaryota,2XH4A@2836|Bacillariophyta	2836|Bacillariophyta	U	Preprotein translocase SecG subunit	secG	-	-	-	-	-	-	-	-	-	-	-	SecG
k141_7445_1	1122194.AUHU01000007_gene317	3.35e-83	265.0	COG0018@1|root,COG0018@2|Bacteria,1MU4J@1224|Proteobacteria,1RPRC@1236|Gammaproteobacteria,464F2@72275|Alteromonadaceae	1236|Gammaproteobacteria	J	Arginyl-tRNA synthetase	argS	GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	iECABU_c1320.ECABU_c21380,iECNA114_1301.ECNA114_1940,iECSE_1348.ECSE_2111,iECSF_1327.ECSF_1736,iEcolC_1368.EcolC_1756,iJN746.PP_5089,iLF82_1304.LF82_0128,iNRG857_1313.NRG857_09405,iUMNK88_1353.UMNK88_2348,ic_1306.c2291	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
k141_4998_1	1128912.GMES_2362	3.7e-53	187.0	COG0086@1|root,COG0086@2|Bacteria,1MU3M@1224|Proteobacteria,1RPYH@1236|Gammaproteobacteria,46403@72275|Alteromonadaceae	1236|Gammaproteobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	GO:0000428,GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030880,GO:0032774,GO:0032991,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
k141_70_1	1380367.JIBC01000005_gene3339	6.98e-69	223.0	COG0520@1|root,COG0520@2|Bacteria,1NIKU@1224|Proteobacteria,2U0AC@28211|Alphaproteobacteria,3ZV25@60136|Sulfitobacter	28211|Alphaproteobacteria	E	Aminotransferase class-V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
k141_6845_1	754477.Q7C_1445	7.36e-40	145.0	COG3437@1|root,COG3437@2|Bacteria,1MUB8@1224|Proteobacteria,1RPH3@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Response regulator containing a CheY-like receiver domain and an HD-GYP domain	rpfG	-	-	ko:K07814,ko:K13815	ko02020,ko02024,map02020,map02024	M00517	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HD,HD_5,Response_reg
k141_1922_1	1203554.HMPREF1476_02136	3.01e-28	117.0	COG1452@1|root,COG1452@2|Bacteria,1MUJC@1224|Proteobacteria,2VIJ7@28216|Betaproteobacteria,4PQR3@995019|Sutterellaceae	28216|Betaproteobacteria	M	Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane	lptD	-	-	ko:K04744	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	OstA,OstA_C
k141_4999_1	1049564.TevJSym_ah00170	7.74e-79	247.0	COG0686@1|root,COG0686@2|Bacteria,1QTX1@1224|Proteobacteria,1T1JB@1236|Gammaproteobacteria,1J4WY@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Belongs to the AlaDH PNT family	ald	-	1.4.1.1	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	-	R00396	RC00008	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
k141_9320_1	1265313.HRUBRA_02120	6.07e-38	143.0	COG4623@1|root,COG4623@2|Bacteria,1MWDS@1224|Proteobacteria,1RM8W@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella	mltF2	GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944	-	ko:K18691	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	SBP_bac_3,SLT
k141_6846_1	189753.AXAS01000006_gene2449	4.84e-22	100.0	COG1752@1|root,COG1752@2|Bacteria,1Q82E@1224|Proteobacteria,2TU9N@28211|Alphaproteobacteria,3JTC1@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Esterase of the alpha-beta hydrolase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Patatin
k141_3764_1	1304275.C41B8_08770	2.91e-84	278.0	COG0525@1|root,COG0525@2|Bacteria,1MV7B@1224|Proteobacteria,1RNEB@1236|Gammaproteobacteria	1236|Gammaproteobacteria	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	GO:0000287,GO:0002161,GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006417,GO:0006418,GO:0006438,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0016070,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019222,GO:0019538,GO:0019752,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0034248,GO:0034250,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045727,GO:0045903,GO:0046483,GO:0046872,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0052689,GO:0060255,GO:0061475,GO:0065007,GO:0065008,GO:0071704,GO:0080090,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:2000112	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iECH74115_1262.ECH74115_5779,iECNA114_1301.ECNA114_4481,iECO26_1355.ECO26_5428,iECSP_1301.ECSP_5359,iECs_1301.ECs5235,iG2583_1286.G2583_5088,iJN746.PP_0977,iSBO_1134.SBO_4182,iSSON_1240.SSON_4443,iYL1228.KPN_04663,iZ_1308.Z5870	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
k141_5000_1	929712.KI912613_gene4087	2.5e-14	77.4	COG5362@1|root,COG5410@1|root,COG5362@2|Bacteria,COG5410@2|Bacteria,2IEA1@201174|Actinobacteria	201174|Actinobacteria	S	TIGRFAM Phage	-	-	-	-	-	-	-	-	-	-	-	-	Terminase_6,Terminase_6C
k141_3765_1	391595.RLO149_c019570	2.28e-111	323.0	COG0745@1|root,COG0745@2|Bacteria,1MWVI@1224|Proteobacteria,2TRSP@28211|Alphaproteobacteria,2P21A@2433|Roseobacter	28211|Alphaproteobacteria	K	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	ctrA	GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141	-	ko:K02483,ko:K13584	ko02020,ko04112,map02020,map04112	M00512	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
k141_686_1	1042377.AFPJ01000024_gene815	6.35e-43	154.0	COG1253@1|root,COG1253@2|Bacteria,1MWT3@1224|Proteobacteria,1RQBC@1236|Gammaproteobacteria,465JI@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	COG1253 Hemolysins and related proteins containing CBS domains	-	-	-	-	-	-	-	-	-	-	-	-	CBS,DUF21
k141_9321_1	159749.E7BWL6	2.24e-141	416.0	COG0443@1|root,KOG0102@2759|Eukaryota,2XAKJ@2836|Bacillariophyta	2759|Eukaryota	O	heat shock	dnaK	GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005739,GO:0006605,GO:0006810,GO:0006886,GO:0006950,GO:0008104,GO:0008144,GO:0008150,GO:0009266,GO:0009408,GO:0009409,GO:0009507,GO:0009526,GO:0009532,GO:0009536,GO:0009570,GO:0009579,GO:0009628,GO:0009941,GO:0010035,GO:0010038,GO:0015031,GO:0015833,GO:0017076,GO:0030554,GO:0031967,GO:0031975,GO:0032553,GO:0032555,GO:0032559,GO:0033036,GO:0033365,GO:0034613,GO:0035639,GO:0036094,GO:0042221,GO:0042886,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0045036,GO:0045184,GO:0046686,GO:0046907,GO:0048046,GO:0050896,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0070727,GO:0071702,GO:0071705,GO:0072594,GO:0072596,GO:0072598,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	ko:K03283	ko03040,ko04010,ko04141,ko04144,ko04213,ko04612,ko04915,ko05134,ko05145,ko05162,ko05164,ko05169,map03040,map04010,map04141,map04144,map04213,map04612,map04915,map05134,map05145,map05162,map05164,map05169	M00353,M00355	-	-	ko00000,ko00001,ko00002,ko01009,ko03009,ko03029,ko03041,ko03051,ko03110,ko04131,ko04147,ko04516	1.A.33.1	-	-	HSP70
k141_1924_1	314265.R2601_00765	1.95e-41	148.0	COG1721@1|root,COG1721@2|Bacteria,1Q7RR@1224|Proteobacteria,2TTXZ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	conserved protein (some members contain a von Willebrand factor type A (vWA) domain)	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
k141_2538_1	2850.Phatr43345	1.15e-75	251.0	2D0ZX@1|root,2SG6M@2759|Eukaryota,2XFQF@2836|Bacillariophyta	2836|Bacillariophyta	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_8068_1	411471.SUBVAR_06307	3.03e-36	138.0	COG1640@1|root,COG1640@2|Bacteria,1W5VQ@1239|Firmicutes,25E46@186801|Clostridia,3WGN6@541000|Ruminococcaceae	186801|Clostridia	G	Psort location Cytoplasmic, score	-	-	2.4.1.25	ko:K00705	ko00500,ko01100,map00500,map01100	-	R05196	RC00049	ko00000,ko00001,ko01000	-	GH77	-	Glyco_hydro_77
k141_687_1	1038869.AXAN01000016_gene1409	8.74e-19	84.0	COG4566@1|root,COG4566@2|Bacteria,1N6WR@1224|Proteobacteria,2WEMY@28216|Betaproteobacteria,1KHSU@119060|Burkholderiaceae	28216|Betaproteobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
k141_6848_1	1304885.AUEY01000080_gene1033	1.95e-66	216.0	COG2801@1|root,COG2801@2|Bacteria,1PFYJ@1224|Proteobacteria,439VW@68525|delta/epsilon subdivisions,2X5A0@28221|Deltaproteobacteria,2MP3D@213118|Desulfobacterales	28221|Deltaproteobacteria	L	Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_6238_1	1123401.JHYQ01000028_gene3161	6.21e-49	167.0	COG5473@1|root,COG5473@2|Bacteria,1MVRU@1224|Proteobacteria,1RPJA@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF2189
k141_1925_2	1260251.SPISAL_07495	6.49e-23	92.0	COG0049@1|root,COG0049@2|Bacteria,1MXC8@1224|Proteobacteria,1RN77@1236|Gammaproteobacteria,1WWE7@135613|Chromatiales	135613|Chromatiales	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA	rpsG	-	-	ko:K02992	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S7
k141_5624_1	768671.ThimaDRAFT_0575	4.06e-70	228.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,1RPN9@1236|Gammaproteobacteria,1WWMD@135613|Chromatiales	135613|Chromatiales	S	of ABC transporters with duplicated ATPase	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,ABC_tran_Xtn
k141_9322_1	887898.HMPREF0551_1896	2.61e-19	81.3	COG0198@1|root,COG0198@2|Bacteria,1MZQD@1224|Proteobacteria,2VUC6@28216|Betaproteobacteria,1K8C0@119060|Burkholderiaceae	28216|Betaproteobacteria	J	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit	rplX	-	-	ko:K02895	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KOW,ribosomal_L24
k141_9322_2	391615.ABSJ01000049_gene1556	6.82e-66	205.0	COG0094@1|root,COG0094@2|Bacteria,1MUU9@1224|Proteobacteria,1RPE1@1236|Gammaproteobacteria,1J50H@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits	rplE	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02931	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L5,Ribosomal_L5_C
k141_1306_1	349521.HCH_03646	1.56e-40	153.0	COG0642@1|root,COG0784@1|root,COG4564@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,COG4564@2|Bacteria,1NRP8@1224|Proteobacteria,1SKTW@1236|Gammaproteobacteria,1XH82@135619|Oceanospirillales	135619|Oceanospirillales	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,Response_reg,dCache_2,sCache_2
k141_1926_1	1461694.ATO9_00280	7.35e-17	79.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1MU7B@1224|Proteobacteria,2TRHQ@28211|Alphaproteobacteria,2PD7X@252301|Oceanicola	28211|Alphaproteobacteria	E	Glutamate synthase central domain	gltB	-	1.4.1.13,1.4.1.14,1.4.7.1	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	-	R00021,R00093,R00114,R00248,R10086	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
k141_1926_2	1288298.rosmuc_00108	4.64e-62	203.0	COG0493@1|root,COG0493@2|Bacteria,1MU2H@1224|Proteobacteria,2TSE2@28211|Alphaproteobacteria,46NDT@74030|Roseovarius	28211|Alphaproteobacteria	C	COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases	gltD	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	Fer4_20,Pyr_redox_2
k141_2617_1	391593.RCCS2_01429	1.21e-22	92.0	COG1399@1|root,COG1399@2|Bacteria,1N7C2@1224|Proteobacteria,2UC4J@28211|Alphaproteobacteria,2P38X@2433|Roseobacter	28211|Alphaproteobacteria	S	Uncharacterized ACR, COG1399	-	-	-	ko:K07040	-	-	-	-	ko00000	-	-	-	DUF177
k141_2617_2	391593.RCCS2_01434	3.32e-36	122.0	COG0333@1|root,COG0333@2|Bacteria,1Q46H@1224|Proteobacteria,2VAP6@28211|Alphaproteobacteria,2P3KJ@2433|Roseobacter	28211|Alphaproteobacteria	J	Belongs to the bacterial ribosomal protein bL32 family	rpmF	-	-	ko:K02911	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_L32p
k141_1381_1	290397.Adeh_3633	2.39e-14	69.7	COG1100@1|root,COG1100@2|Bacteria,1R6NS@1224|Proteobacteria,42NIX@68525|delta/epsilon subdivisions,2WJ44@28221|Deltaproteobacteria,2YU2F@29|Myxococcales	28221|Deltaproteobacteria	S	ADP-ribosylation factor family	mglA	GO:0008150,GO:0032879,GO:0032880,GO:0050789,GO:0065007	-	ko:K06883	-	-	-	-	ko00000	-	-	-	Arf,Ras
k141_1381_2	1254432.SCE1572_42245	2.67e-45	150.0	COG1100@1|root,COG1100@2|Bacteria,1R6NS@1224|Proteobacteria,42NIX@68525|delta/epsilon subdivisions,2WJ44@28221|Deltaproteobacteria,2YU2F@29|Myxococcales	28221|Deltaproteobacteria	S	ADP-ribosylation factor family	mglA	GO:0008150,GO:0032879,GO:0032880,GO:0050789,GO:0065007	-	ko:K06883	-	-	-	-	ko00000	-	-	-	Arf,Ras
k141_1381_3	1121918.ARWE01000001_gene254	6.25e-15	71.6	COG2018@1|root,COG2018@2|Bacteria,1RDN5@1224|Proteobacteria,42S13@68525|delta/epsilon subdivisions,2WNKB@28221|Deltaproteobacteria,43T83@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	PFAM Roadblock LC7 family protein	mglB	-	-	-	-	-	-	-	-	-	-	-	Robl_LC7
k141_764_1	1027273.GZ77_17760	1.51e-26	108.0	COG1752@1|root,COG1752@2|Bacteria,1MU6Z@1224|Proteobacteria,1RPW6@1236|Gammaproteobacteria,1XIC5@135619|Oceanospirillales	135619|Oceanospirillales	S	Esterase of the alpha-beta hydrolase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_141_1	1430331.EP10_06260	3.9e-07	54.7	COG3335@1|root,COG3335@2|Bacteria,1V41H@1239|Firmicutes,4HH52@91061|Bacilli,1WEBA@129337|Geobacillus	91061|Bacilli	L	PFAM Integrase catalytic region	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,HTH_29,HTH_33
k141_3224_1	666509.RCA23_c23400	1.15e-109	320.0	COG3316@1|root,COG3316@2|Bacteria,1P9SM@1224|Proteobacteria,2TV17@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	COG3316 Transposase and inactivated derivatives	-	-	-	ko:K07498	-	-	-	-	ko00000	-	-	-	DDE_Tnp_IS240
k141_3840_1	862908.BMS_1128	4.39e-61	192.0	COG1432@1|root,COG1432@2|Bacteria,1QC1U@1224|Proteobacteria,42TAH@68525|delta/epsilon subdivisions,2WPYX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	NYN domain	-	-	-	-	-	-	-	-	-	-	-	-	NYN
k141_1382_1	32042.PstZobell_05343	2.25e-34	135.0	COG3459@1|root,COG3459@2|Bacteria,1MVNX@1224|Proteobacteria,1RMW9@1236|Gammaproteobacteria,1Z06B@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	G	Cellobiose phosphorylase	chbP	-	2.4.1.20,2.4.1.280	ko:K00702,ko:K13688,ko:K18675	ko00500,ko00520,ko01100,map00500,map00520,map01100	-	R00952,R09942	RC00049	ko00000,ko00001,ko01000,ko01003	-	GH94,GT36,GT84	-	Glyco_hydro_36,Glyco_transf_36,Glycoamylase
k141_5694_1	1229909.NSED_08875	4.11e-108	331.0	COG0640@1|root,COG1328@1|root,arCOG01680@2157|Archaea,arCOG04889@2157|Archaea,41SBG@651137|Thaumarchaeota	651137|Thaumarchaeota	FK	Anaerobic ribonucleoside-triphosphate reductase	-	-	1.1.98.6	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R11633,R11634,R11635,R11636	RC00613	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-cone,HTH_20,NRDD
k141_4470_1	1547437.LL06_26705	1.06e-27	114.0	COG2271@1|root,COG2271@2|Bacteria,1MVV4@1224|Proteobacteria,2TS66@28211|Alphaproteobacteria,43K0R@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
k141_8139_1	247639.MGP2080_08791	1.75e-84	258.0	COG1410@1|root,COG1410@2|Bacteria,1MV6G@1224|Proteobacteria,1RZF4@1236|Gammaproteobacteria,1J9S4@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	E	COG1410 Methionine synthase I, cobalamin-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Pterin_bind
k141_5083_1	504487.JCM19302_4140	8.28e-157	447.0	COG0008@1|root,COG0008@2|Bacteria,4NFCC@976|Bacteroidetes,1HXAH@117743|Flavobacteriia	976|Bacteroidetes	J	Catalyzes a two-step reaction, first charging a glutamine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA	glnS	-	6.1.1.18	ko:K01886	ko00970,ko01100,map00970,map01100	M00359,M00360	R03652	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1c,tRNA-synt_1c_C
k141_9401_1	1229909.NSED_01295	1.25e-134	388.0	COG0649@1|root,arCOG01548@2157|Archaea,41S62@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Belongs to the complex I 49 kDa subunit family	-	-	1.6.5.3	ko:K00333	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_49kDa
k141_1383_1	743721.Psesu_1779	3.83e-22	95.5	COG0114@1|root,COG0114@2|Bacteria,1MUQI@1224|Proteobacteria,1RNUS@1236|Gammaproteobacteria,1X3ED@135614|Xanthomonadales	135614|Xanthomonadales	C	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate	fumC	-	4.2.1.2	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	M00009,M00011,M00173,M00376	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	FumaraseC_C,Lyase_1
k141_1383_2	574966.KB898647_gene2502	1.13e-44	158.0	COG0015@1|root,COG0015@2|Bacteria,1MV4B@1224|Proteobacteria,1RN93@1236|Gammaproteobacteria,1XHPF@135619|Oceanospirillales	135619|Oceanospirillales	F	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	purB	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ASL_C,Lyase_1
k141_5695_1	1191523.MROS_0927	8.97e-33	126.0	COG2208@1|root,COG2208@2|Bacteria	2|Bacteria	T	phosphoserine phosphatase activity	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	-
k141_8748_1	367336.OM2255_11430	6.19e-112	331.0	COG0687@1|root,COG0687@2|Bacteria,1N9KN@1224|Proteobacteria,2TXYK@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Spermidine putrescine-binding periplasmic protein	-	-	-	ko:K11069	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	SBP_bac_8
k141_5084_1	1346791.M529_03845	1.59e-108	318.0	COG4974@1|root,COG4974@2|Bacteria,1NY1A@1224|Proteobacteria,2UTXZ@28211|Alphaproteobacteria,2KEK1@204457|Sphingomonadales	204457|Sphingomonadales	L	Transposase IS66 family	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS66,DDE_Tnp_IS66_C,LZ_Tnp_IS66,zf-IS66
k141_2005_1	573370.DMR_16480	3.14e-08	51.6	2DMNG@1|root,32SP1@2|Bacteria,1NAN7@1224|Proteobacteria,430M6@68525|delta/epsilon subdivisions,2WVZ8@28221|Deltaproteobacteria,2MF5N@213115|Desulfovibrionales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_7506_1	159749.K0TBT8	2.09e-25	115.0	COG2801@1|root,KOG0017@2759|Eukaryota,2XEGG@2836|Bacillariophyta	159749.K0TBT8|-	L	transposition, RNA-mediated	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_144_1	416348.Hlac_1706	2.85e-06	51.6	COG0589@1|root,arCOG00449@2157|Archaea,2XU1P@28890|Euryarchaeota,23SZU@183963|Halobacteria	183963|Halobacteria	T	COG0589 Universal stress protein UspA and related nucleotide-binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	Fer2,Usp
k141_144_2	713586.KB900536_gene2867	1.98e-16	80.1	COG3213@1|root,COG3213@2|Bacteria,1MUJK@1224|Proteobacteria,1RMCR@1236|Gammaproteobacteria,1WXCQ@135613|Chromatiales	135613|Chromatiales	P	PFAM NnrS family protein	-	-	-	ko:K07234	-	-	-	-	ko00000	-	-	-	NnrS
k141_5696_1	909663.KI867150_gene2732	9.76e-90	271.0	COG2152@1|root,COG2152@2|Bacteria,1MX8M@1224|Proteobacteria,42QDF@68525|delta/epsilon subdivisions,2WMG5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	beta-1,4-mannooligosaccharide phosphorylase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_130
k141_3843_1	1080067.BAZH01000021_gene2997	5.66e-57	187.0	COG1187@1|root,COG1187@2|Bacteria,1MUCE@1224|Proteobacteria,1RQU0@1236|Gammaproteobacteria,3WWRP@544|Citrobacter	1236|Gammaproteobacteria	J	S4 RNA-binding domain	rluB	GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	5.4.99.22	ko:K06178	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
k141_2006_1	935261.JAGL01000079_gene1065	8.86e-68	221.0	COG4372@1|root,COG4372@2|Bacteria,1MUCX@1224|Proteobacteria,2TR59@28211|Alphaproteobacteria,43KZJ@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	Transposase C of IS166 homeodomain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS66,DDE_Tnp_IS66_C,LZ_Tnp_IS66,zf-IS66
k141_1384_1	1122135.KB893134_gene3130	1.54e-41	149.0	COG0001@1|root,COG0001@2|Bacteria,1MUY5@1224|Proteobacteria,2TU8Q@28211|Alphaproteobacteria	28211|Alphaproteobacteria	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3,CTP_transf_3
k141_1384_2	247639.MGP2080_04855	4.46e-21	91.7	COG1233@1|root,COG1233@2|Bacteria,1MV2R@1224|Proteobacteria,1RSGI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	COG1233 Phytoene dehydrogenase and related proteins	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
k141_8602_1	1208321.D104_08780	2.29e-37	132.0	COG2049@1|root,COG2049@2|Bacteria,1MWRB@1224|Proteobacteria,1RQIQ@1236|Gammaproteobacteria,1XHH1@135619|Oceanospirillales	135619|Oceanospirillales	E	Allophanate hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	CT_C_D
k141_8602_2	225937.HP15_2687	5.36e-12	64.7	COG1984@1|root,COG1984@2|Bacteria,1MU9H@1224|Proteobacteria,1RR39@1236|Gammaproteobacteria,466NG@72275|Alteromonadaceae	1236|Gammaproteobacteria	E	Allophanate hydrolase subunit 2	-	-	-	-	-	-	-	-	-	-	-	-	CT_A_B
k141_5017_1	391595.RLO149_c020160	8.22e-104	311.0	COG1494@1|root,COG1494@2|Bacteria,1MUB1@1224|Proteobacteria,2TSPE@28211|Alphaproteobacteria,2P2IM@2433|Roseobacter	28211|Alphaproteobacteria	G	COG1494 Fructose-1,6-bisphosphatase sedoheptulose 1,7-bisphosphatase and related proteins	glpX	-	3.1.3.11,3.1.3.37	ko:K02446,ko:K11532	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00165,M00167	R00762,R01845,R04780	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FBPase_glpX
k141_2552_1	1231392.OCGS_1604	2.79e-117	356.0	COG0317@1|root,COG0317@2|Bacteria,1MU44@1224|Proteobacteria,2TQNY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	spoT	-	2.7.6.5,3.1.7.2	ko:K00951,ko:K01139	ko00230,map00230	-	R00336,R00429	RC00002,RC00078	ko00000,ko00001,ko01000,ko03009	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
k141_3778_1	1298593.TOL_0598	2.82e-62	200.0	COG0030@1|root,COG0030@2|Bacteria,1MVNU@1224|Proteobacteria,1RMHW@1236|Gammaproteobacteria,1XIZA@135619|Oceanospirillales	135619|Oceanospirillales	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	-	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
k141_3778_2	1268635.Loa_00363	4.67e-26	105.0	COG0262@1|root,COG1995@1|root,COG0262@2|Bacteria,COG1995@2|Bacteria,1MX5W@1224|Proteobacteria,1RNZV@1236|Gammaproteobacteria,1JCGN@118969|Legionellales	118969|Legionellales	H	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)	pdxA	-	1.1.1.262	ko:K00097	ko00750,ko01100,map00750,map01100	M00124	R05681,R05837,R07406	RC00089,RC00675,RC01475	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxA
k141_4404_1	159749.E7BWH1	1.98e-89	277.0	28JG1@1|root,2QRV6@2759|Eukaryota,2XEM0@2836|Bacillariophyta	2836|Bacillariophyta	P	One of the components of the core complex of photosystem II (PSII). It binds chlorophyll and helps catalyze the primary light-induced photochemical processes of PSII. PSII is a light- driven water plastoquinone oxidoreductase, using light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation	psbB	-	-	ko:K02704	ko00195,ko01100,map00195,map01100	M00161	-	-	ko00000,ko00001,ko00002,ko00194	-	-	-	PSII
k141_2553_1	684719.HIMB114_00002320	5.8e-55	183.0	COG3181@1|root,COG3181@2|Bacteria,1PHI8@1224|Proteobacteria,2V8Q7@28211|Alphaproteobacteria,4BT4N@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
k141_3779_1	713586.KB900536_gene1177	9.71e-79	262.0	COG0085@1|root,COG0085@2|Bacteria,1MUC4@1224|Proteobacteria,1RMK0@1236|Gammaproteobacteria,1WX4P@135613|Chromatiales	135613|Chromatiales	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	-	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
k141_6252_1	1220582.RRU01S_07_04700	5.95e-24	96.3	COG2249@1|root,COG2249@2|Bacteria,1PW1D@1224|Proteobacteria,2U1SJ@28211|Alphaproteobacteria,4BMW1@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Flavodoxin-like fold	-	-	-	-	-	-	-	-	-	-	-	-	Flavodoxin_2
k141_6252_2	754035.Mesau_03605	1.67e-26	107.0	COG0402@1|root,COG0402@2|Bacteria,1MX34@1224|Proteobacteria,2U0Z1@28211|Alphaproteobacteria,43K30@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	F	Amidohydrolase family	codAch2	GO:0003674,GO:0003824,GO:0016787,GO:0016810,GO:0016814,GO:0019239,GO:0050228,GO:0050279	3.5.4.1	ko:K01485	ko00240,ko00330,ko01100,map00240,map00330,map01100	-	R00974,R01411,R02922	RC00074,RC00514,RC00809	ko00000,ko00001,ko01000	-	-	-	Amidohydro_3
k141_5018_1	1380394.JADL01000011_gene3947	4.89e-105	317.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,2TRJV@28211|Alphaproteobacteria,2JP8V@204441|Rhodospirillales	204441|Rhodospirillales	C	Aldehyde dehydrogenase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldedh
k141_7458_1	698769.JFBD01000003_gene2892	1.53e-19	90.9	COG3344@1|root,COG3344@2|Bacteria,1TP9A@1239|Firmicutes,4HC0U@91061|Bacilli,4C6RM@84406|Virgibacillus	91061|Bacilli	L	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	GIIM,RVT_1
k141_6864_1	1178482.BJB45_11275	1.76e-57	192.0	COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,1RYJ7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	Tripartite ATP-independent periplasmic transporter, DctM component	-	-	-	-	-	-	-	-	-	-	-	-	DctM
k141_9339_1	234267.Acid_6720	1.26e-55	189.0	COG1228@1|root,COG1228@2|Bacteria,3Y6Y2@57723|Acidobacteria	57723|Acidobacteria	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
k141_1941_1	95619.PM1_0209115	8.29e-29	118.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1T1IW@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains	fleQ	-	-	ko:K10941	ko02020,ko02025,ko05111,map02020,map02025,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	FleQ,HTH_8,Sigma54_activat
k141_5019_1	35128.Thapsdraft1327	8.13e-65	212.0	COG0305@1|root,2QRXQ@2759|Eukaryota,2XEMK@2836|Bacillariophyta	2836|Bacillariophyta	L	DnaB-like helicase N terminal domain	dnaB	-	-	-	-	-	-	-	-	-	-	-	DnaB,DnaB_C
k141_5633_1	634500.EbC_42660	6.04e-13	68.2	COG0524@1|root,COG3892@1|root,COG0524@2|Bacteria,COG3892@2|Bacteria,1MV6I@1224|Proteobacteria,1RQGH@1236|Gammaproteobacteria,3X4NZ@551|Erwinia	1236|Gammaproteobacteria	G	myo-inositol catabolism protein	iolC	-	2.7.1.92	ko:K03338	ko00562,ko01100,ko01120,map00562,map01100,map01120	-	R05661	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	DUF2090,KduI,PfkB
k141_704_2	330214.NIDE1310	2.29e-53	169.0	COG0051@1|root,COG0051@2|Bacteria,3J0P3@40117|Nitrospirae	40117|Nitrospirae	J	Involved in the binding of tRNA to the ribosomes	rpsJ	-	-	ko:K02946	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S10
k141_1942_1	566466.NOR53_2596	8.54e-68	221.0	COG5361@1|root,COG5361@2|Bacteria,1NX2A@1224|Proteobacteria,1RZYZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	s cog5361	-	-	-	-	-	-	-	-	-	-	-	-	DUF1214,DUF1254
k141_8084_1	644107.SL1157_2090	4.39e-111	332.0	COG0154@1|root,COG0154@2|Bacteria,1MUVQ@1224|Proteobacteria,2TRFY@28211|Alphaproteobacteria,4NARI@97050|Ruegeria	28211|Alphaproteobacteria	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
k141_4408_1	620914.JH621247_gene3071	8.9e-22	86.7	COG0184@1|root,COG0184@2|Bacteria,4NS7U@976|Bacteroidetes,1I3ZI@117743|Flavobacteriia,2YJVI@290174|Aquimarina	976|Bacteroidetes	J	Ribosomal_S15	rpsO	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
k141_5634_1	159749.K0QZP2	2.81e-26	112.0	COG0507@1|root,COG2801@1|root,KOG0017@2759|Eukaryota,KOG0987@2759|Eukaryota,2XG4E@2836|Bacillariophyta	2759|Eukaryota	L	PIF1-like helicase	-	-	-	-	-	-	-	-	-	-	-	-	Helitron_like_N,PIF1
k141_87_2	4096.XP_009781880.1	1.24e-10	71.6	COG2801@1|root,KOG0017@2759|Eukaryota,37RIF@33090|Viridiplantae	33090|Viridiplantae	O	Cysteine-rich RLK (RECEPTOR-like protein kinase) 8	-	-	-	-	-	-	-	-	-	-	-	-	RVT_2,Retrotran_gag_2,Retrotran_gag_3,Retrotrans_gag,gag_pre-integrs,rve
k141_5021_1	631362.Thi970DRAFT_02744	4.73e-32	128.0	COG0591@1|root,COG0591@2|Bacteria,1MUBI@1224|Proteobacteria,1RMXU@1236|Gammaproteobacteria,1WXIE@135613|Chromatiales	135613|Chromatiales	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K11928	-	-	-	-	ko00000,ko02000	2.A.21.2	-	-	SSF
k141_707_1	1380600.AUYN01000007_gene3142	2.09e-120	364.0	COG0557@1|root,COG0557@2|Bacteria,4NE7T@976|Bacteroidetes,1HWPN@117743|Flavobacteriia	976|Bacteroidetes	J	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs	rnr	-	-	ko:K12573,ko:K12585	ko03018,map03018	M00391	-	-	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	OB_RNB,RNB,S1
k141_4411_1	35128.Thaps21858	5.28e-77	249.0	COG0488@1|root,KOG0927@2759|Eukaryota,2XEI2@2836|Bacillariophyta	2836|Bacillariophyta	S	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,ABC_tran_Xtn
k141_1946_1	391596.PBAL39_19854	1.6e-54	178.0	COG1611@1|root,COG1611@2|Bacteria,4NF20@976|Bacteroidetes,1IQFQ@117747|Sphingobacteriia	976|Bacteroidetes	S	Belongs to the LOG family	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
k141_8700_1	632245.CLP_4449	4.15e-14	68.2	2CW0Y@1|root,32SYT@2|Bacteria,1V76P@1239|Firmicutes,25FS4@186801|Clostridia,36UZ5@31979|Clostridiaceae	186801|Clostridia	S	the current gene model (or a revised gene model) may contain a premature stop	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_5023_1	382464.ABSI01000005_gene1340	1.45e-91	280.0	COG2895@1|root,COG2895@2|Bacteria,46SN4@74201|Verrucomicrobia,2ITI4@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily	-	-	2.7.1.25,2.7.7.4	ko:K00955	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176	R00509,R00529,R04928,R04929	RC00002,RC00078,RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_EFTU
k141_1329_2	1288826.MSNKSG1_00086	2.31e-18	82.8	COG0313@1|root,COG0313@2|Bacteria,1MU0E@1224|Proteobacteria,1RM7U@1236|Gammaproteobacteria,463Z3@72275|Alteromonadaceae	1236|Gammaproteobacteria	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA	rsmI	GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070677,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
k141_1947_1	1304275.C41B8_08590	4.19e-100	308.0	COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,1RMQQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	H	acetolactate synthase	ilvI	GO:0000287,GO:0003674,GO:0003824,GO:0003984,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0019842,GO:0030976,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901681	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	iAPECO1_1312.APECO1_1907,iB21_1397.B21_00078,iBWG_1329.BWG_0073,iECBD_1354.ECBD_3539,iECB_1328.ECB_00079,iECD_1391.ECD_00079,iUTI89_1310.UTI89_C0085,iYL1228.KPN_00082	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
k141_3170_1	1458427.BAWN01000033_gene1902	3.54e-110	326.0	COG1740@1|root,COG1740@2|Bacteria,1MWAC@1224|Proteobacteria,2VK03@28216|Betaproteobacteria,4AD7X@80864|Comamonadaceae	28216|Betaproteobacteria	C	NiFe/NiFeSe hydrogenase small subunit C-terminal	hoxK	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	1.12.99.6	ko:K06282	ko00633,ko01120,map00633,map01120	-	R08034	RC00250	ko00000,ko00001,ko01000	-	-	-	NiFe_hyd_SSU_C,Oxidored_q6
k141_6259_1	1026882.MAMP_02952	7.32e-29	119.0	COG0668@1|root,COG0668@2|Bacteria,1MY0I@1224|Proteobacteria,1RQKY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	mechanosensitive ion channel	ybiO	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K22044	-	-	-	-	ko00000,ko02000	1.A.23.3	-	-	MS_channel
k141_5638_1	521098.Aaci_1468	4.31e-16	79.0	COG1426@1|root,COG1426@2|Bacteria,1V1N7@1239|Firmicutes,4HKW3@91061|Bacilli	91061|Bacilli	S	Protein conserved in bacteria	ymfM	-	-	ko:K15539	-	-	-	-	ko00000	-	-	-	DUF4115,HTH_25
k141_3786_2	159749.E7BWH3	1.3e-19	79.3	2EFVA@1|root,2S8EW@2759|Eukaryota	2759|Eukaryota	U	photosynthesis	psbN	-	-	ko:K02715	-	-	-	-	ko00000	-	-	-	PsbN
k141_8701_1	666685.R2APBS1_0378	2.09e-48	170.0	COG0773@1|root,COG0773@2|Bacteria,1MUC5@1224|Proteobacteria,1RMMT@1236|Gammaproteobacteria,1X4Y7@135614|Xanthomonadales	135614|Xanthomonadales	M	Reutilizes the intact tripeptide L-alanyl-gamma-D- glutamyl-meso-diaminopimelate by linking it to UDP-N- acetylmuramate	mpl	-	6.3.2.45	ko:K02558	-	-	-	-	ko00000,ko01000	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
k141_2557_1	754477.Q7C_1916	3.7e-09	55.1	COG0711@1|root,COG0711@2|Bacteria,1RHZ0@1224|Proteobacteria,1S402@1236|Gammaproteobacteria,460SP@72273|Thiotrichales	72273|Thiotrichales	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	atpF	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
k141_2557_2	754477.Q7C_1915	4.01e-71	218.0	COG0712@1|root,COG0712@2|Bacteria,1MVRH@1224|Proteobacteria,1S8X2@1236|Gammaproteobacteria,46125@72273|Thiotrichales	72273|Thiotrichales	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpH	-	-	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	OSCP
k141_9346_1	1293048.CBMB010000004_gene1624	4.21e-28	116.0	COG1884@1|root,arCOG04232@2157|Archaea,2XU3F@28890|Euryarchaeota,23THD@183963|Halobacteria	183963|Halobacteria	I	COG1884 Methylmalonyl-CoA mutase, N-terminal domain subunit	mmcA2	-	5.4.99.2	ko:K01848	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
k141_6870_1	1408418.JNJH01000007_gene1350	1.11e-19	95.9	COG1007@1|root,COG1007@2|Bacteria,1MV56@1224|Proteobacteria,2TQMX@28211|Alphaproteobacteria,2JQ1V@204441|Rhodospirillales	204441|Rhodospirillales	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
k141_6870_2	45157.CMW005CT	4.74e-22	96.3	COG0839@1|root,2S66Q@2759|Eukaryota	2759|Eukaryota	C	NADH-ubiquinone/plastoquinone oxidoreductase chain 6	nad6	-	1.6.5.3	ko:K03884	ko00190,ko01100,ko04714,ko04723,ko05012,map00190,map01100,map04714,map04723,map05012	M00142	R11945	RC00061	ko00000,ko00001,ko00002,ko01000,ko03029	3.D.1.6	-	-	Oxidored_q3
k141_8088_1	314285.KT71_07969	6.45e-99	305.0	COG0465@1|root,COG0465@2|Bacteria,1MU6J@1224|Proteobacteria,1RME8@1236|Gammaproteobacteria,1J4WR@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	GO:0000166,GO:0003674,GO:0003824,GO:0004175,GO:0004176,GO:0004222,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0008270,GO:0009056,GO:0009057,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030145,GO:0030163,GO:0030554,GO:0031224,GO:0031226,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043273,GO:0044238,GO:0044425,GO:0044459,GO:0044464,GO:0046872,GO:0046914,GO:0070011,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0098796,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
k141_5639_1	159749.K0S109	6.02e-20	87.8	2CZQV@1|root,2SBAE@2759|Eukaryota	2759|Eukaryota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_1331_1	1229909.NSED_00640	1.21e-163	469.0	COG0519@1|root,arCOG00085@2157|Archaea,41SDI@651137|Thaumarchaeota	651137|Thaumarchaeota	F	Catalyzes the synthesis of GMP from XMP	guaA	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase
k141_2559_1	314285.KT71_02272	7.76e-105	319.0	COG0568@1|root,COG0568@2|Bacteria,1MVNJ@1224|Proteobacteria,1RMQI@1236|Gammaproteobacteria,1J4NF@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	rpoD	GO:0000988,GO:0000990,GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006352,GO:0006355,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016987,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031326,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043254,GO:0044087,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2000142,GO:2001141	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_ner,Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
k141_6871_1	519989.ECTPHS_07102	4.85e-24	103.0	COG1007@1|root,COG1007@2|Bacteria,1MV56@1224|Proteobacteria,1RPJB@1236|Gammaproteobacteria,1WW6G@135613|Chromatiales	135613|Chromatiales	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
k141_6871_2	399795.CtesDRAFT_PD3939	1.05e-10	62.4	COG1008@1|root,COG1008@2|Bacteria,1MV7V@1224|Proteobacteria,2VIAX@28216|Betaproteobacteria,4AAN9@80864|Comamonadaceae	28216|Betaproteobacteria	C	TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M	nuoM	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q5_N,Proton_antipo_M
k141_7466_1	754477.Q7C_2677	2.56e-62	194.0	COG1399@1|root,COG1399@2|Bacteria,1PGKW@1224|Proteobacteria,1RRK3@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	metal-binding, possibly nucleic acid-binding protein	yceD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K07040	-	-	-	-	ko00000	-	-	-	DUF177
k141_7466_2	1286106.MPL1_07822	4.45e-29	104.0	COG0333@1|root,COG0333@2|Bacteria,1N6RF@1224|Proteobacteria,1SC9G@1236|Gammaproteobacteria,46158@72273|Thiotrichales	72273|Thiotrichales	J	Belongs to the bacterial ribosomal protein bL32 family	rpmF	-	-	ko:K02911	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_L32p
k141_9349_1	745014.OMB55_00009970	1.56e-77	244.0	COG0015@1|root,COG0015@2|Bacteria,1MV4B@1224|Proteobacteria,1RN93@1236|Gammaproteobacteria,1J4V5@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	F	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	purB	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ASL_C,Lyase_1
k141_1949_1	159749.E7BWD0	1.95e-82	249.0	COG0052@1|root,KOG0832@2759|Eukaryota,2XE8D@2836|Bacillariophyta	2836|Bacillariophyta	J	Ribosomal protein S2	-	GO:0000313,GO:0000314,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005761,GO:0005763,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009507,GO:0009536,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0031974,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0070013,GO:0071704,GO:0098798,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	-	-	-	-	-	-	-	-	-	Ribosomal_S2
k141_4489_2	992406.RIA_0281	2.48e-31	112.0	COG0759@1|root,COG0759@2|Bacteria,4NV1N@976|Bacteroidetes,1I3W5@117743|Flavobacteriia	976|Bacteroidetes	S	Could be involved in insertion of integral membrane proteins into the membrane	yidD	-	-	ko:K08998	-	-	-	-	ko00000	-	-	-	Haemolytic
k141_2640_1	1123060.JONP01000008_gene4531	6.43e-19	84.0	COG1250@1|root,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,2TR8E@28211|Alphaproteobacteria,2JPY1@204441|Rhodospirillales	204441|Rhodospirillales	I	Dehydrogenase	hbdA	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
k141_5103_1	1121013.P873_11290	7.38e-64	204.0	COG0057@1|root,COG0057@2|Bacteria,1MU93@1224|Proteobacteria,1RMBM@1236|Gammaproteobacteria,1X34S@135614|Xanthomonadales	135614|Xanthomonadales	G	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	gapA	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
k141_5103_2	34506.g1329	1.39e-05	46.2	COG0057@1|root,COG0126@1|root,KOG0657@2759|Eukaryota,KOG1367@2759|Eukaryota,38DPH@33154|Opisthokonta,3BA6Z@33208|Metazoa,3CRFX@33213|Bilateria,40FCJ@6231|Nematoda,1KUTI@119089|Chromadorea,40XK7@6236|Rhabditida	33208|Metazoa	G	Glyceraldehyde-3-phosphate dehydrogenase	-	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
k141_6953_1	398580.Dshi_3303	1.01e-98	298.0	COG2370@1|root,COG2370@2|Bacteria,1MV6Z@1224|Proteobacteria,2TSX2@28211|Alphaproteobacteria	28211|Alphaproteobacteria	O	membrane	-	-	-	-	-	-	-	-	-	-	-	-	HupE_UreJ_2
k141_164_1	1250005.PHEL85_1317	6.91e-61	205.0	COG0376@1|root,COG0376@2|Bacteria,4NG30@976|Bacteroidetes,1HWMX@117743|Flavobacteriia,3VVYV@52959|Polaribacter	976|Bacteroidetes	C	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity	katG	-	1.11.1.21	ko:K03782	ko00360,ko00380,ko00940,ko00983,ko01100,ko01110,map00360,map00380,map00940,map00983,map01100,map01110	-	R00602,R00698,R02596,R02670,R03919,R04007,R07443,R11906	RC00034,RC00213,RC00767,RC02141	ko00000,ko00001,ko01000	-	-	-	peroxidase
k141_2550_1	330214.NIDE3420	1.26e-15	76.6	COG0472@1|root,COG0472@2|Bacteria	2|Bacteria	M	phospho-N-acetylmuramoyl-pentapeptide-transferase activity	-	-	2.7.8.33,2.7.8.35	ko:K02851	-	-	R08856	RC00002	ko00000,ko01000,ko01003,ko01005	-	-	-	CoA_binding_3,Glycos_transf_4
k141_3776_1	1288826.MSNKSG1_01983	1.6e-116	347.0	COG3239@1|root,COG3239@2|Bacteria,1MY4I@1224|Proteobacteria,1S726@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	Fatty acid desaturase	-	-	1.14.19.23,1.14.19.45	ko:K10255	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase
k141_8079_1	318161.Sden_0468	4.97e-58	189.0	COG0407@1|root,COG0407@2|Bacteria,1MUG1@1224|Proteobacteria,1RMDH@1236|Gammaproteobacteria,2Q9CE@267890|Shewanellaceae	1236|Gammaproteobacteria	H	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III	hemE	GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006536,GO:0006725,GO:0006778,GO:0006779,GO:0006780,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009064,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019353,GO:0019438,GO:0019752,GO:0033013,GO:0033014,GO:0033526,GO:0034641,GO:0042168,GO:0042440,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046394,GO:0046483,GO:0046501,GO:0046502,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	iPC815.YPO3734,iSBO_1134.SBO_4018	URO-D
k141_8079_2	697282.Mettu_1128	1.83e-13	68.6	COG0284@1|root,COG0284@2|Bacteria,1MW2C@1224|Proteobacteria,1RNJR@1236|Gammaproteobacteria,1XEBB@135618|Methylococcales	135618|Methylococcales	F	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)	pyrF	GO:0003674,GO:0003824,GO:0004590,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase
k141_5016_1	1178825.ALIH01000019_gene1228	6.22e-84	249.0	COG0622@1|root,COG0622@2|Bacteria,4NM4G@976|Bacteroidetes,1I19W@117743|Flavobacteriia	976|Bacteroidetes	S	Phosphoesterase	-	-	-	ko:K07095	-	-	-	-	ko00000	-	-	-	Metallophos_2
k141_700_1	1127673.GLIP_1446	2.02e-87	266.0	COG0179@1|root,COG0179@2|Bacteria,1MV0V@1224|Proteobacteria,1RNYV@1236|Gammaproteobacteria,465V2@72275|Alteromonadaceae	1236|Gammaproteobacteria	Q	COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)	uptA	-	3.7.1.2	ko:K16171	ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120	M00044	R01364	RC00326,RC00446	ko00000,ko00001,ko00002,ko01000	-	-	-	FAA_hydrolase
k141_8696_1	35128.Thapsdraft633	3.54e-57	203.0	2D4B4@1|root,2SUIV@2759|Eukaryota,2XHU1@2836|Bacillariophyta	2836|Bacillariophyta	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_1938_1	391593.RCCS2_12569	1.44e-60	195.0	COG1984@1|root,COG1984@2|Bacteria,1MU9H@1224|Proteobacteria,2TS7P@28211|Alphaproteobacteria,2P0XR@2433|Roseobacter	28211|Alphaproteobacteria	E	COG1984 Allophanate hydrolase subunit 2	MA20_13140	-	3.5.1.54	ko:K01457	ko00220,ko00791,ko01100,ko01120,map00220,map00791,map01100,map01120	-	R00005	RC02756	ko00000,ko00001,ko01000	-	-	-	CT_A_B
k141_1938_2	314232.SKA53_14436	8.5e-35	125.0	COG1540@1|root,COG1540@2|Bacteria,1MUYV@1224|Proteobacteria,2TQUC@28211|Alphaproteobacteria,2P9W1@245186|Loktanella	28211|Alphaproteobacteria	S	LamB/YcsF family	-	-	-	ko:K07160	-	-	-	-	ko00000	-	-	-	LamB_YcsF
k141_5629_1	159749.K0RL31	2.21e-223	676.0	COG2801@1|root,KOG0017@2759|Eukaryota,2XF4I@2836|Bacillariophyta	159749.K0RL31|-	L	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_9336_1	1131553.JIBI01000035_gene2030	5.73e-23	102.0	COG0535@1|root,COG0535@2|Bacteria,1MU07@1224|Proteobacteria,2W8V7@28216|Betaproteobacteria,372JU@32003|Nitrosomonadales	28216|Betaproteobacteria	S	Radical SAM superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM
k141_83_2	467661.RKLH11_3059	7.84e-30	115.0	COG3279@1|root,COG3300@1|root,COG3279@2|Bacteria,COG3300@2|Bacteria,1PXIQ@1224|Proteobacteria,2TT3B@28211|Alphaproteobacteria,3ZI00@58840|unclassified Rhodobacteraceae	28211|Alphaproteobacteria	KT	LytTr DNA-binding domain	coxC	GO:0006355,GO:0006808,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141	-	ko:K21696	-	-	-	-	ko00000,ko03000	-	-	-	LytTR,MHYT
k141_1321_1	1167006.UWK_01312	9.14e-81	268.0	COG0167@1|root,COG0493@1|root,COG0167@2|Bacteria,COG0493@2|Bacteria,1MU2H@1224|Proteobacteria	1224|Proteobacteria	C	glutamate synthase	ygfK	GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0016491,GO:0043167,GO:0043169,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0055114	1.97.1.9	ko:K12527	ko00450,map00450	-	R07229	RC02420	ko00000,ko00001,ko01000	-	-	-	Fer4_20,Pyr_redox_2,Pyr_redox_3
k141_6862_1	46429.BV95_03723	3.49e-57	186.0	COG0778@1|root,COG0778@2|Bacteria,1PG8V@1224|Proteobacteria,2U6HW@28211|Alphaproteobacteria,2K9X8@204457|Sphingomonadales	204457|Sphingomonadales	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
k141_8697_1	1168059.KB899087_gene4045	7.3e-105	311.0	COG0022@1|root,COG0022@2|Bacteria,1R8KB@1224|Proteobacteria,2TRFK@28211|Alphaproteobacteria,3EY87@335928|Xanthobacteraceae	28211|Alphaproteobacteria	C	Transketolase, pyrimidine binding domain	-	-	-	ko:K21417	-	-	-	-	ko00000,ko01000	-	-	-	Transket_pyr,Transketolase_C
k141_701_1	331869.BAL199_28445	4.66e-144	412.0	COG0330@1|root,COG0330@2|Bacteria,1MV7R@1224|Proteobacteria,2TRP4@28211|Alphaproteobacteria,4BPGN@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	O	HflC and HflK could regulate a protease	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
k141_4403_1	1121937.AUHJ01000018_gene212	1.35e-31	122.0	COG0340@1|root,COG1654@1|root,COG0340@2|Bacteria,COG1654@2|Bacteria,1MWCC@1224|Proteobacteria,1RNGC@1236|Gammaproteobacteria,465FU@72275|Alteromonadaceae	1236|Gammaproteobacteria	K	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon	birA	GO:0000166,GO:0000976,GO:0000984,GO:0001017,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0004077,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0006082,GO:0006464,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009305,GO:0009374,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0017053,GO:0017076,GO:0017144,GO:0018130,GO:0018271,GO:0019538,GO:0019752,GO:0019842,GO:0030554,GO:0031406,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0032991,GO:0033218,GO:0033293,GO:0034641,GO:0035639,GO:0036094,GO:0036211,GO:0042364,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043565,GO:0043603,GO:0043604,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0046983,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681,GO:1990837	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_C,BPL_LplA_LipB,HTH_11
k141_5704_2	1123070.KB899254_gene1253	3.41e-31	113.0	COG0222@1|root,COG0222@2|Bacteria,46SWC@74201|Verrucomicrobia,2IUI8@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation	rplL	-	-	ko:K02935	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L12,Ribosomal_L12_N
k141_8143_1	323261.Noc_2088	1.28e-23	103.0	COG1527@1|root,COG1527@2|Bacteria,1R7PV@1224|Proteobacteria,1S0C2@1236|Gammaproteobacteria,1WWZK@135613|Chromatiales	135613|Chromatiales	C	(C AC39) subunit	-	-	-	ko:K02119	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	vATP-synt_AC39
k141_8756_1	196490.AUEZ01000017_gene3211	1.93e-89	291.0	COG1014@1|root,COG4231@1|root,COG1014@2|Bacteria,COG4231@2|Bacteria,1MUKS@1224|Proteobacteria,2TSHH@28211|Alphaproteobacteria,3JVSS@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	Pyruvate ferredoxin/flavodoxin oxidoreductase	MA20_06130	-	1.2.7.8	ko:K04090	-	-	-	-	br01601,ko00000,ko01000	-	-	-	POR,TPP_enzyme_C
k141_7513_1	247633.GP2143_14311	8.36e-55	186.0	COG3202@1|root,COG3202@2|Bacteria,1MVP5@1224|Proteobacteria,1RNY6@1236|Gammaproteobacteria,1JAB2@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	COG3202 ATP ADP translocase	-	-	-	ko:K03301	-	-	-	-	ko00000	2.A.12	-	-	MFS_1,TLC
k141_2629_1	351016.RAZWK3B_13129	1.65e-58	187.0	COG4105@1|root,COG4105@2|Bacteria,1MVS5@1224|Proteobacteria,2TRZ5@28211|Alphaproteobacteria,2P2AR@2433|Roseobacter	28211|Alphaproteobacteria	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamD	-	-	ko:K05807	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	YfiO
k141_2629_2	1288298.rosmuc_02916	1.58e-48	168.0	COG0497@1|root,COG0497@2|Bacteria,1MUNP@1224|Proteobacteria,2TREW@28211|Alphaproteobacteria,46NKA@74030|Roseovarius	28211|Alphaproteobacteria	L	May be involved in recombinational repair of damaged DNA	recN	-	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	SMC_N
k141_4480_1	1127673.GLIP_1210	1.43e-107	327.0	COG4805@1|root,COG4805@2|Bacteria,1MUBX@1224|Proteobacteria,1RMT7@1236|Gammaproteobacteria,466B9@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Bacterial protein of unknown function (DUF885)	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
k141_6943_1	1123229.AUBC01000015_gene4692	3.02e-42	149.0	COG1226@1|root,2Z7ZD@2|Bacteria,1MXKM@1224|Proteobacteria,2TSNZ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	Ion transport protein	-	-	-	ko:K08714	-	-	-	-	ko00000,ko02000	1.A.1.14	-	-	Ion_trans
k141_6943_2	159087.Daro_0960	7.75e-14	70.9	COG1009@1|root,COG1009@2|Bacteria,1MW2M@1224|Proteobacteria,2VJ2J@28216|Betaproteobacteria,2KUJW@206389|Rhodocyclales	206389|Rhodocyclales	CP	COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit	nuoL	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M,Proton_antipo_N
k141_5094_1	983545.Glaag_2024	2.74e-83	262.0	COG0318@1|root,COG0318@2|Bacteria,1MUMC@1224|Proteobacteria,1RMGS@1236|Gammaproteobacteria,46625@72275|Alteromonadaceae	1236|Gammaproteobacteria	IQ	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II	alkK	-	6.2.1.44	ko:K20034	ko00920,map00920	-	R10820	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C
k141_1390_1	1229909.NSED_01105	3.5e-104	302.0	COG1146@1|root,arCOG04548@2157|Archaea,41SI0@651137|Thaumarchaeota	651137|Thaumarchaeota	C	PFAM 4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4
k141_6332_1	2340.JV46_26720	3.01e-103	315.0	COG0374@1|root,COG0374@2|Bacteria,1MWFJ@1224|Proteobacteria,1RMC3@1236|Gammaproteobacteria,1JARP@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Nickel-dependent hydrogenase	hydB	-	1.12.5.1,1.12.99.6	ko:K05922,ko:K06281	ko00633,ko01120,map00633,map01120	-	R08034	RC00250	ko00000,ko00001,ko01000	-	-	-	NiFeSe_Hases
k141_5705_1	52598.EE36_16987	1.06e-112	332.0	COG0472@1|root,COG0472@2|Bacteria,1MUTK@1224|Proteobacteria,2TRUG@28211|Alphaproteobacteria,3ZVDE@60136|Sulfitobacter	28211|Alphaproteobacteria	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	-	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	-	Glycos_transf_4,MraY_sig1
k141_2630_1	252305.OB2597_01082	2.18e-55	180.0	COG3090@1|root,COG3090@2|Bacteria,1R3YK@1224|Proteobacteria,2TU4N@28211|Alphaproteobacteria,2PDZU@252301|Oceanicola	28211|Alphaproteobacteria	G	Tripartite ATP-independent periplasmic transporters, DctQ component	dctQ	-	-	ko:K11689	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.56.1	-	-	DctQ
k141_4481_1	640081.Dsui_0126	2.87e-56	189.0	COG0247@1|root,COG1139@1|root,COG0247@2|Bacteria,COG1139@2|Bacteria,1MV6J@1224|Proteobacteria,2VJ3Y@28216|Betaproteobacteria,2KU8D@206389|Rhodocyclales	206389|Rhodocyclales	C	Domain of unknown function (DUF3390)	-	-	-	ko:K18929	-	-	-	-	ko00000	-	-	-	DUF3390,Fer4_8,LUD_dom
k141_9412_1	589873.EP13_12695	5.51e-100	297.0	COG0171@1|root,COG0171@2|Bacteria,1QHZ4@1224|Proteobacteria,1SZSC@1236|Gammaproteobacteria,46CZK@72275|Alteromonadaceae	1236|Gammaproteobacteria	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source	nadE	GO:0003674,GO:0003824,GO:0003952,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008795,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016874,GO:0016879,GO:0016880,GO:0016884,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0033554,GO:0034355,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043094,GO:0043173,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0050896,GO:0051186,GO:0051188,GO:0051716,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	6.3.1.5	ko:K01916	ko00760,ko01100,map00760,map01100	M00115	R00189	RC00100	ko00000,ko00001,ko00002,ko01000	-	-	iETEC_1333.ETEC_1772,iSFV_1184.SFV_1480,iSF_1195.SF1486,iSFxv_1172.SFxv_1676,iS_1188.S1603	NAD_synthase
k141_8145_1	1121405.dsmv_2298	2.52e-85	275.0	COG0045@1|root,COG1042@1|root,COG1247@1|root,COG0045@2|Bacteria,COG1042@2|Bacteria,COG1247@2|Bacteria,1MW98@1224|Proteobacteria,42KZW@68525|delta/epsilon subdivisions,2WIQB@28221|Deltaproteobacteria,2MIWX@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM CoA-binding domain protein	acs	-	6.2.1.13	ko:K01905,ko:K09181,ko:K22224	ko00010,ko00620,ko00640,ko01100,ko01120,map00010,map00620,map00640,map01100,map01120	-	R00229,R00920	RC00004,RC00012,RC00014	ko00000,ko00001,ko01000,ko01004	-	-	-	ATP-grasp_5,Acetyltransf_1,Acetyltransf_3,CoA_binding_2,Succ_CoA_lig
k141_776_2	159749.E7BWM9	7.34e-35	120.0	COG0198@1|root,KOG1708@2759|Eukaryota	2759|Eukaryota	J	structural constituent of ribosome	rpl24	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009507,GO:0009526,GO:0009532,GO:0009536,GO:0009570,GO:0009657,GO:0009941,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022625,GO:0022626,GO:0031967,GO:0031975,GO:0032544,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02895	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KOW,ribosomal_L24
k141_776_3	159749.E7BWN0	4.84e-63	199.0	COG0094@1|root,KOG0398@2759|Eukaryota	2759|Eukaryota	J	structural constituent of ribosome	rpl5	GO:0000027,GO:0000313,GO:0000315,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005761,GO:0005762,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009507,GO:0009536,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0031974,GO:0032543,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070013,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:0098798,GO:0140053,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02931	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L5,Ribosomal_L5_C
k141_153_2	7029.ACYPI073473-PA	1.6e-05	48.9	2EA4H@1|root,2SZ18@2759|Eukaryota,38VIS@33154|Opisthokonta,3C5X1@33208|Metazoa,3DR66@33213|Bilateria,428IV@6656|Arthropoda,3SSBM@50557|Insecta	7029.ACYPI073473-PA|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_4482_1	391613.RTM1035_17147	9.24e-29	107.0	COG0711@1|root,COG0711@2|Bacteria,1MZGU@1224|Proteobacteria,2UBVW@28211|Alphaproteobacteria,46Q8X@74030|Roseovarius	28211|Alphaproteobacteria	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	atpF2	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
k141_4482_2	985054.JQEZ01000002_gene3709	4.84e-26	97.8	COG0636@1|root,COG0636@2|Bacteria,1MZBU@1224|Proteobacteria,2UFPN@28211|Alphaproteobacteria,4NCM0@97050|Ruegeria	28211|Alphaproteobacteria	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpE	-	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
k141_3235_1	159749.K0S6F1	4.65e-67	233.0	COG2801@1|root,KOG0017@2759|Eukaryota,2XEDA@2836|Bacillariophyta	2836|Bacillariophyta	L	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	RVT_2
k141_7515_1	1278073.MYSTI_02808	8.51e-12	65.5	COG3342@1|root,COG3342@2|Bacteria,1MWQT@1224|Proteobacteria	1224|Proteobacteria	S	major pilin protein fima	MA20_16755	-	-	-	-	-	-	-	-	-	-	-	DUF1028
k141_7515_2	565045.NOR51B_2784	6.67e-40	146.0	COG2234@1|root,COG2234@2|Bacteria,1NE83@1224|Proteobacteria,1RN9P@1236|Gammaproteobacteria,1J5NE@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	peptidase	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
k141_8146_1	555778.Hneap_0209	1.01e-23	99.0	COG0174@1|root,COG0174@2|Bacteria,1MUGQ@1224|Proteobacteria,1RMD1@1236|Gammaproteobacteria,1WVZ2@135613|Chromatiales	135613|Chromatiales	E	TIGRFAM glutamine synthetase, type I	glnA	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
k141_6945_1	857087.Metme_0805	6.67e-131	389.0	COG0459@1|root,COG0459@2|Bacteria,1MURR@1224|Proteobacteria,1RMTB@1236|Gammaproteobacteria,1XER9@135618|Methylococcales	135618|Methylococcales	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	-	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
k141_2017_1	653733.Selin_2609	1.87e-26	113.0	COG0243@1|root,COG0243@2|Bacteria	2|Bacteria	C	molybdopterin cofactor binding	-	-	1.8.5.5	ko:K08352	ko00920,ko01120,map00920,map01120	-	R10149	RC02823	ko00000,ko00001,ko01000,ko02000	5.A.3.5	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding,TAT_signal
k141_5096_1	1342302.JASC01000002_gene74	6.93e-79	249.0	COG0577@1|root,COG0577@2|Bacteria,1MVN1@1224|Proteobacteria,2TTEF@28211|Alphaproteobacteria	1224|Proteobacteria	V	ABC-type antimicrobial peptide transport system, permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	MacB_PCD
k141_2632_1	713586.KB900536_gene3031	1.26e-125	376.0	COG0443@1|root,COG0443@2|Bacteria,1MVEN@1224|Proteobacteria,1RMDD@1236|Gammaproteobacteria,1WVW2@135613|Chromatiales	135613|Chromatiales	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
k141_1393_1	1415780.JPOG01000001_gene2810	5.99e-79	242.0	COG0714@1|root,COG0714@2|Bacteria,1MV5I@1224|Proteobacteria,1RQ62@1236|Gammaproteobacteria,1X3MM@135614|Xanthomonadales	135614|Xanthomonadales	S	AAA domain (Cdc48 subfamily)	-	-	-	-	-	-	-	-	-	-	-	-	AAA,AAA_5
k141_5707_1	715226.ABI_10250	9.37e-18	88.2	COG2373@1|root,COG2931@1|root,COG2373@2|Bacteria,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,2TRVY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	COG2931 RTX toxins and related Ca2 -binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	HemolysinCabind
k141_8147_1	754436.JCM19237_4254	3.84e-22	100.0	COG2982@1|root,COG2982@2|Bacteria,1NVUY@1224|Proteobacteria,1RPFM@1236|Gammaproteobacteria,1XSC9@135623|Vibrionales	135623|Vibrionales	M	protein involved in outer membrane biogenesis	asmA	-	-	ko:K07289	-	-	-	-	ko00000	-	-	-	AsmA
k141_3856_1	472759.Nhal_0064	3.03e-78	241.0	COG1845@1|root,COG1845@2|Bacteria,1MUCK@1224|Proteobacteria,1RN9D@1236|Gammaproteobacteria,1WX89@135613|Chromatiales	135613|Chromatiales	C	PFAM cytochrome c oxidase, subunit III	-	-	1.9.3.1	ko:K02276	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.6	-	-	COX3
k141_8760_1	1173028.ANKO01000017_gene194	5.21e-32	128.0	COG0745@1|root,COG2203@1|root,COG2208@1|root,COG0745@2|Bacteria,COG2203@2|Bacteria,COG2208@2|Bacteria,1G3MK@1117|Cyanobacteria,1H9X2@1150|Oscillatoriales	1117|Cyanobacteria	T	PFAM Sporulation stage II, protein E C-terminal	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	GAF,GAF_2,HAMP,SpoIIE
k141_156_2	1116472.MGMO_94c00440	1.75e-50	162.0	COG0139@1|root,COG0139@2|Bacteria,1MW67@1224|Proteobacteria,1RMV4@1236|Gammaproteobacteria,1XF4K@135618|Methylococcales	135618|Methylococcales	E	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP	hisI	GO:0000105,GO:0003674,GO:0003824,GO:0004635,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016787,GO:0016810,GO:0016814,GO:0018130,GO:0019238,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	3.5.4.19	ko:K01496	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04037	RC01055	ko00000,ko00001,ko00002,ko01000	-	-	-	PRA-CH
k141_6946_1	420324.KI912080_gene8208	7.77e-124	363.0	COG0517@1|root,COG0517@2|Bacteria,1MXI6@1224|Proteobacteria,2TS6X@28211|Alphaproteobacteria,1JX9I@119045|Methylobacteriaceae	28211|Alphaproteobacteria	S	Putative transposase	-	-	-	-	-	-	-	-	-	-	-	-	Y2_Tnp,Zn_Tnp_IS91
k141_5097_1	159749.E7BWH1	4.08e-143	415.0	28JG1@1|root,2QRV6@2759|Eukaryota,2XEM0@2836|Bacillariophyta	2836|Bacillariophyta	P	One of the components of the core complex of photosystem II (PSII). It binds chlorophyll and helps catalyze the primary light-induced photochemical processes of PSII. PSII is a light- driven water plastoquinone oxidoreductase, using light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation	psbB	-	-	ko:K02704	ko00195,ko01100,map00195,map01100	M00161	-	-	ko00000,ko00001,ko00002,ko00194	-	-	-	PSII
k141_1394_1	243233.MCA0290	6.04e-132	388.0	COG0518@1|root,COG0519@1|root,COG0518@2|Bacteria,COG0519@2|Bacteria,1MU2A@1224|Proteobacteria,1RP81@1236|Gammaproteobacteria,1XDZD@135618|Methylococcales	135618|Methylococcales	F	Catalyzes the synthesis of GMP from XMP	guaA	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase
k141_8148_1	519989.ECTPHS_11050	2.6e-95	294.0	COG1053@1|root,COG1053@2|Bacteria,1MU5M@1224|Proteobacteria,1RMU2@1236|Gammaproteobacteria,1WW72@135613|Chromatiales	135613|Chromatiales	C	Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily	sdhA	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
k141_3239_1	1120953.AUBH01000010_gene87	1.19e-50	182.0	COG1629@1|root,COG4771@2|Bacteria,1N6JG@1224|Proteobacteria,1RP10@1236|Gammaproteobacteria,465FE@72275|Alteromonadaceae	1236|Gammaproteobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
k141_5710_1	713587.THITH_15600	5.12e-33	120.0	COG2922@1|root,COG2922@2|Bacteria,1RD5F@1224|Proteobacteria,1S43X@1236|Gammaproteobacteria,1WYZ6@135613|Chromatiales	135613|Chromatiales	S	Belongs to the Smg family	smg	-	-	ko:K03747	-	-	-	-	ko00000	-	-	-	DUF494
k141_3858_1	1116472.MGMO_53c00190	1.02e-48	170.0	COG0303@1|root,COG0303@2|Bacteria,1MVD5@1224|Proteobacteria,1RMQU@1236|Gammaproteobacteria,1XEJX@135618|Methylococcales	135618|Methylococcales	H	MoeA N-terminal region (domain I	-	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
k141_2020_1	2850.Phatr47185	1.25e-16	80.1	2CXRQ@1|root,2RZ9T@2759|Eukaryota	2759|Eukaryota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3
k141_2020_2	2850.Phatr47185	7.44e-28	112.0	2CXRQ@1|root,2RZ9T@2759|Eukaryota	2759|Eukaryota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3
k141_6948_1	1158150.KB906247_gene2368	6.72e-37	129.0	COG0242@1|root,COG0242@2|Bacteria,1RA2P@1224|Proteobacteria,1S247@1236|Gammaproteobacteria,1WXF4@135613|Chromatiales	135613|Chromatiales	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
k141_8149_1	35128.Thapsdraft2050	1.74e-49	179.0	COG0086@1|root,2RUNH@2759|Eukaryota,2XF5V@2836|Bacillariophyta	2836|Bacillariophyta	H	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC2	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009536,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464	-	-	-	-	-	-	-	-	-	-	RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
k141_8762_1	35128.Thapsdraft308	3.1e-30	108.0	2E6G4@1|root,2S9HV@2759|Eukaryota,2XH2Q@2836|Bacillariophyta	2836|Bacillariophyta	S	Photosystem I reaction centre subunit IV / PsaE	-	-	-	ko:K02693	ko00195,ko01100,map00195,map01100	M00163	-	-	ko00000,ko00001,ko00002,ko00194	-	-	-	PSI_PsaE
k141_4485_2	1120956.JHZK01000007_gene2921	7.61e-52	167.0	COG0607@1|root,COG0607@2|Bacteria,1RHQZ@1224|Proteobacteria,2U9DZ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	rhodanese-related sulfurtransferase	MA20_01310	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
k141_4485_3	998088.B565_3779	7.62e-24	95.1	COG3040@1|root,COG3040@2|Bacteria,1RDAI@1224|Proteobacteria,1S3PW@1236|Gammaproteobacteria,1Y4GK@135624|Aeromonadales	135624|Aeromonadales	M	Lipocalin-like domain	-	-	-	ko:K03098	-	-	-	-	ko00000,ko04147	-	-	-	Lipocalin_2
k141_5711_1	159087.Daro_1547	2.08e-82	265.0	COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,2VH0Y@28216|Betaproteobacteria,2KU6T@206389|Rhodocyclales	206389|Rhodocyclales	I	3-hydroxyacyl-CoA dehydrogenase	-	-	1.1.1.35,4.2.1.17,5.1.2.3	ko:K01782	ko00071,ko00280,ko00281,ko00310,ko00362,ko00380,ko00410,ko00640,ko00650,ko00903,ko00930,ko01040,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00071,map00280,map00281,map00310,map00362,map00380,map00410,map00640,map00650,map00903,map00930,map01040,map01100,map01110,map01120,map01130,map01200,map01212	M00032,M00087	R01975,R03026,R03045,R03276,R04137,R04170,R04203,R04204,R04224,R04737,R04738,R04739,R04740,R04741,R04744,R04745,R04746,R04748,R04749,R05066,R05305,R06411,R06412,R06941,R06942,R07935,R07951,R08093,R08094	RC00029,RC00099,RC00117,RC00241,RC00525,RC00831,RC00834,RC00896,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	3HCDH,3HCDH_N,ECH_1
k141_9418_1	205922.Pfl01_2765	4.89e-89	274.0	COG2826@1|root,COG2826@2|Bacteria,1PP49@1224|Proteobacteria,1RN7B@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	COG2826 Transposase and inactivated derivatives, IS30 family	insI	GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0004803,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006310,GO:0006313,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0030983,GO:0032135,GO:0032196,GO:0032991,GO:0032993,GO:0034641,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363	-	ko:K07482	-	-	-	-	ko00000	-	-	-	HTH_38,rve
k141_4486_1	1131553.JIBI01000010_gene1362	1.35e-73	241.0	COG0475@1|root,COG1226@1|root,COG0475@2|Bacteria,COG1226@2|Bacteria,1MV34@1224|Proteobacteria,2VHQQ@28216|Betaproteobacteria,374MC@32003|Nitrosomonadales	28216|Betaproteobacteria	P	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family	kefB	-	-	ko:K03455	-	-	-	-	ko00000	2.A.37	-	-	Na_H_Exchanger,TrkA_C,TrkA_N
k141_3241_1	1229909.NSED_00015	2.08e-158	446.0	COG0648@1|root,arCOG01894@2157|Archaea,41SDW@651137|Thaumarchaeota	651137|Thaumarchaeota	L	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin	nfo	-	3.1.21.2	ko:K01151	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AP_endonuc_2
k141_782_1	314232.SKA53_08954	5.42e-122	362.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,2TS7G@28211|Alphaproteobacteria,2P83Z@245186|Loktanella	28211|Alphaproteobacteria	S	ABC transporter	chvD	-	-	ko:K15738	-	-	-	-	ko00000,ko02000	3.A.1.120.6	-	-	ABC_tran,ABC_tran_Xtn
k141_6950_1	1197906.CAJQ02000014_gene362	3.73e-50	162.0	COG3415@1|root,COG3415@2|Bacteria,1N7CS@1224|Proteobacteria,2UFAY@28211|Alphaproteobacteria,3K4UF@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	HTH_23,HTH_Tnp_IS630
k141_4487_1	207954.MED92_17728	2.46e-36	134.0	COG1622@1|root,COG1622@2|Bacteria,1MWHZ@1224|Proteobacteria,1RP4H@1236|Gammaproteobacteria,1XIU7@135619|Oceanospirillales	135619|Oceanospirillales	C	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)	coxB	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2,COX2_TM,Cytochrome_CBB3
k141_3860_1	1089552.KI911559_gene494	4.31e-100	305.0	COG2317@1|root,COG2317@2|Bacteria,1MW7T@1224|Proteobacteria,2TSMY@28211|Alphaproteobacteria,2JP9Q@204441|Rhodospirillales	204441|Rhodospirillales	E	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues	-	-	3.4.17.19	ko:K01299	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M32
k141_1398_1	349521.HCH_05202	1.7e-103	316.0	COG0511@1|root,COG5016@1|root,COG0511@2|Bacteria,COG5016@2|Bacteria,1QTTG@1224|Proteobacteria,1RNG6@1236|Gammaproteobacteria,1XIFS@135619|Oceanospirillales	135619|Oceanospirillales	CI	Oxaloacetate decarboxylase	oadA	-	4.1.1.3	ko:K01571	ko00620,ko01100,map00620,map01100	-	R00217	RC00040	ko00000,ko00001,ko01000,ko02000	3.B.1.1.1	-	-	Biotin_lipoyl,HMGL-like,PYC_OADA
k141_8764_1	392500.Swoo_4378	5.53e-90	293.0	28HKI@1|root,2Z7VC@2|Bacteria,1MW0I@1224|Proteobacteria,1RQ5H@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_4507_1	765913.ThidrDRAFT_2532	2.22e-29	119.0	COG3864@1|root,COG3864@2|Bacteria,1MY13@1224|Proteobacteria,1RXX2@1236|Gammaproteobacteria,1WX24@135613|Chromatiales	135613|Chromatiales	S	VWA-like domain (DUF2201)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2201,DUF2201_N
k141_5123_1	768671.ThimaDRAFT_0205	4.4e-73	229.0	COG1087@1|root,COG1087@2|Bacteria,1MUHI@1224|Proteobacteria,1RMTU@1236|Gammaproteobacteria,1WWNR@135613|Chromatiales	135613|Chromatiales	M	Belongs to the NAD(P)-dependent epimerase dehydratase family	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
k141_7538_1	765910.MARPU_04075	3.59e-19	85.1	COG1212@1|root,COG1212@2|Bacteria,1MUUU@1224|Proteobacteria,1RMAE@1236|Gammaproteobacteria,1WWTZ@135613|Chromatiales	135613|Chromatiales	M	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria	kdsB	-	2.7.7.38	ko:K00979	ko00540,ko01100,map00540,map01100	M00063	R03351,R11396	RC00152,RC00910	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_3
k141_7538_2	1348635.BBJY01000008_gene1837	4.45e-53	176.0	COG0494@1|root,COG0494@2|Bacteria,1RDMW@1224|Proteobacteria,1RPZV@1236|Gammaproteobacteria,1XUUC@135623|Vibrionales	135623|Vibrionales	L	COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes	nudF	-	3.6.1.13	ko:K01515	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
k141_805_1	266834.SMc02498	1.18e-07	52.8	COG0712@1|root,COG0712@2|Bacteria,1MVRH@1224|Proteobacteria,2U5IC@28211|Alphaproteobacteria,4BA3I@82115|Rhizobiaceae	28211|Alphaproteobacteria	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpH	-	-	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	OSCP
k141_805_2	675635.Psed_4310	6.28e-26	104.0	COG4948@1|root,COG4948@2|Bacteria,2GKSK@201174|Actinobacteria,4E0SP@85010|Pseudonocardiales	201174|Actinobacteria	M	Mandelate racemase / muconate lactonizing enzyme, C-terminal domain	-	-	5.1.2.2	ko:K01781	ko00627,ko01120,map00627,map01120	-	R03791,R04161	RC00998	ko00000,ko00001,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
k141_5124_1	526227.Mesil_0294	4.51e-85	267.0	COG0033@1|root,COG0033@2|Bacteria,1WJDJ@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	Phosphoglucomutase phosphomannomutase alpha beta alpha domain I	-	-	5.4.2.2	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00549	R00959,R01057,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
k141_1419_2	1348657.M622_18965	7.61e-19	88.2	COG1538@1|root,COG1538@2|Bacteria,1MWB0@1224|Proteobacteria,2VIIW@28216|Betaproteobacteria,2KU7C@206389|Rhodocyclales	206389|Rhodocyclales	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
k141_6358_1	1541065.JRFE01000017_gene110	1.15e-18	81.6	COG3195@1|root,COG3195@2|Bacteria,1G67T@1117|Cyanobacteria,3VJTW@52604|Pleurocapsales	1117|Cyanobacteria	S	OHCU decarboxylase	-	-	4.1.1.97	ko:K13485	ko00230,ko01100,map00230,map01100	M00546	R06604	RC01551	ko00000,ko00001,ko00002,ko01000	-	-	-	OHCU_decarbox
k141_6358_2	342113.DM82_2607	9.73e-57	186.0	COG4266@1|root,COG4266@2|Bacteria,1MXJK@1224|Proteobacteria,2VKRI@28216|Betaproteobacteria,1K1GK@119060|Burkholderiaceae	28216|Betaproteobacteria	F	Belongs to the allantoicase family	alc	-	3.5.3.4	ko:K01477	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R02422	RC00379,RC00712	ko00000,ko00001,ko00002,ko01000	-	-	-	Allantoicase
k141_2658_1	1484460.JSWG01000012_gene1325	4.14e-29	106.0	COG0099@1|root,COG0099@2|Bacteria,4NNGZ@976|Bacteroidetes,1I1ZW@117743|Flavobacteriia	976|Bacteroidetes	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	rpsM	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
k141_2658_2	991.IW20_05255	2.64e-42	138.0	COG0361@1|root,COG0361@2|Bacteria,4NS6S@976|Bacteroidetes,1I3WQ@117743|Flavobacteriia,2NX5N@237|Flavobacterium	976|Bacteroidetes	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
k141_2658_3	1178825.ALIH01000001_gene2611	5.39e-11	61.6	COG0201@1|root,COG0201@2|Bacteria,4NEPU@976|Bacteroidetes,1HWR7@117743|Flavobacteriia	976|Bacteroidetes	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	-	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
k141_9440_1	402881.Plav_2107	4e-30	115.0	COG0057@1|root,COG0057@2|Bacteria,1MU93@1224|Proteobacteria,2TR6E@28211|Alphaproteobacteria,1JN30@119043|Rhodobiaceae	28211|Alphaproteobacteria	G	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain	gapA	GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
k141_9440_2	1500897.JQNA01000002_gene2578	6.01e-27	109.0	COG0021@1|root,COG0021@2|Bacteria,1MUEY@1224|Proteobacteria,2VIUD@28216|Betaproteobacteria,1K5JX@119060|Burkholderiaceae	28216|Betaproteobacteria	G	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
k141_5734_1	159749.E7BWK9	3.02e-106	321.0	COG0459@1|root,KOG0356@2759|Eukaryota,2XBJD@2836|Bacillariophyta	2759|Eukaryota	O	Belongs to the chaperonin (HSP60) family	groL	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009536,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
k141_2659_1	1304877.KI519399_gene3600	7.04e-12	70.9	COG3852@1|root,COG3852@2|Bacteria,1NTTH@1224|Proteobacteria,2UQ4Q@28211|Alphaproteobacteria,3K6T5@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	T	Histidine kinase-like ATPases	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_4,PAS_9,Response_reg
k141_186_1	1205680.CAKO01000002_gene2502	1.01e-11	70.9	COG1042@1|root,COG1042@2|Bacteria,1MW98@1224|Proteobacteria,2TR24@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	COG1042 Acyl-CoA synthetase (NDP forming)	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_5,CoA_binding_2,Succ_CoA_lig
k141_807_2	1123367.C666_18585	1.27e-18	86.7	COG1377@1|root,COG1377@2|Bacteria,1MUWI@1224|Proteobacteria,2VIH0@28216|Betaproteobacteria,2KVJ0@206389|Rhodocyclales	206389|Rhodocyclales	N	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin	flhB	-	-	ko:K02401	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	Bac_export_2
k141_8786_1	195105.CN97_04985	1.3e-78	248.0	COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,2TRFB@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Belongs to the peptidase M16 family	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
k141_5126_1	1269813.ATUL01000008_gene1542	1.23e-81	259.0	COG0443@1|root,COG0443@2|Bacteria,1MVEN@1224|Proteobacteria,1RMDD@1236|Gammaproteobacteria,1WVW2@135613|Chromatiales	135613|Chromatiales	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
k141_5126_2	96561.Dole_0069	7.82e-11	62.0	COG0576@1|root,COG0576@2|Bacteria,1RH8T@1224|Proteobacteria,42TM2@68525|delta/epsilon subdivisions,2WQ0U@28221|Deltaproteobacteria,2MJZ6@213118|Desulfobacterales	28221|Deltaproteobacteria	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	GO:0000166,GO:0000774,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0017076,GO:0030234,GO:0030554,GO:0036094,GO:0044424,GO:0044444,GO:0044464,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
k141_6360_1	396588.Tgr7_1289	1.82e-119	366.0	COG0013@1|root,COG0013@2|Bacteria,1MU9A@1224|Proteobacteria,1RMWZ@1236|Gammaproteobacteria,1WXPB@135613|Chromatiales	135613|Chromatiales	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
k141_9442_1	215803.DB30_5881	1.51e-45	166.0	COG3391@1|root,COG3391@2|Bacteria,1R7E0@1224|Proteobacteria,42Z2U@68525|delta/epsilon subdivisions,2WTYD@28221|Deltaproteobacteria,2YX64@29|Myxococcales	28221|Deltaproteobacteria	S	Cytochrome D1 heme domain	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_D1
k141_6976_1	1231392.OCGS_1842	6.49e-18	82.8	COG0683@1|root,COG0683@2|Bacteria,1QURG@1224|Proteobacteria,2TS62@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component	MA20_24635	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_6
k141_6976_2	391593.RCCS2_13374	6.64e-100	316.0	COG2844@1|root,COG2844@2|Bacteria,1MV54@1224|Proteobacteria,2TSV0@28211|Alphaproteobacteria,2P108@2433|Roseobacter	28211|Alphaproteobacteria	O	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen	glnD	GO:0006355,GO:0006464,GO:0006807,GO:0006808,GO:0007154,GO:0007584,GO:0008150,GO:0008152,GO:0009605,GO:0009719,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0009991,GO:0010033,GO:0010243,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0018175,GO:0018177,GO:0019219,GO:0019222,GO:0019538,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031667,GO:0031668,GO:0031669,GO:0031670,GO:0036211,GO:0042221,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0070887,GO:0071310,GO:0071417,GO:0071495,GO:0071496,GO:0071704,GO:0080090,GO:0090293,GO:1901564,GO:1901698,GO:1901699,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141	2.7.7.59	ko:K00990	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	-	-	-	ACT,GlnD_UR_UTase,GlnE,HD,NTP_transf_2
k141_4512_1	1260251.SPISAL_04670	5.86e-104	317.0	COG0559@1|root,COG1413@1|root,COG0559@2|Bacteria,COG1413@2|Bacteria,1MVND@1224|Proteobacteria,1RQXD@1236|Gammaproteobacteria,1WVWT@135613|Chromatiales	135613|Chromatiales	U	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01997,ko:K11960	ko02010,ko02024,map02010,map02024	M00237,M00323	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4,3.A.1.4.4,3.A.1.4.5	-	-	BPD_transp_2,HEAT_2
k141_8787_1	269482.Bcep1808_5202	1.23e-07	54.3	COG0300@1|root,COG0300@2|Bacteria,1NT7C@1224|Proteobacteria,2VK40@28216|Betaproteobacteria,1K4G5@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
k141_1495_1	556268.OFAG_00774	1.15e-74	243.0	COG0465@1|root,COG0465@2|Bacteria,1MU6J@1224|Proteobacteria,2VHEM@28216|Betaproteobacteria,478MR@75682|Oxalobacteraceae	28216|Betaproteobacteria	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	-	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
k141_2730_1	313603.FB2170_03805	2.96e-72	220.0	COG2335@1|root,COG2335@2|Bacteria,4NMPI@976|Bacteroidetes,1I1DK@117743|Flavobacteriia	976|Bacteroidetes	M	COG2335 Secreted and surface protein containing fasciclin-like repeats	-	-	-	-	-	-	-	-	-	-	-	-	Fasciclin
k141_2730_2	1443665.JACA01000047_gene5266	3.1e-38	142.0	COG4263@1|root,COG4263@2|Bacteria,4NFNE@976|Bacteroidetes,1HYUT@117743|Flavobacteriia,2YHS1@290174|Aquimarina	976|Bacteroidetes	C	Nitrous oxide reductase	nosZ	-	1.7.2.4	ko:K00376	ko00910,ko01120,map00910,map01120	M00529	R02804	RC02861	ko00000,ko00001,ko00002,ko01000	-	-	-	-
k141_6434_1	159749.K0S1E8	3.09e-74	277.0	COG2801@1|root,KOG0017@2759|Eukaryota,2XEGG@2836|Bacillariophyta	2836|Bacillariophyta	L	transposition, RNA-mediated	-	-	-	-	-	-	-	-	-	-	-	-	RVT_2,gag_pre-integrs,rve,zf-CCHC
k141_880_1	1049564.TevJSym_bi00160	3.14e-06	48.9	COG4398@1|root,COG4398@2|Bacteria,1MUX9@1224|Proteobacteria,1RPGR@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	PFAM FIST C domain	-	-	-	-	-	-	-	-	-	-	-	-	FIST,FIST_C
k141_880_2	1167006.UWK_02758	3.32e-24	99.0	COG1409@1|root,COG1409@2|Bacteria,1Q9IR@1224|Proteobacteria,42QM7@68525|delta/epsilon subdivisions,2WKP5@28221|Deltaproteobacteria,2MIHX@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
k141_9511_1	870187.Thini_0482	2.43e-56	190.0	COG1100@1|root,COG1100@2|Bacteria,1R1W9@1224|Proteobacteria,1SK3H@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Domain of unknown function (DUF697)	-	-	-	-	-	-	-	-	-	-	-	-	DUF697,MMR_HSR1
k141_5809_1	1288494.EBAPG3_23180	3.22e-65	217.0	COG0358@1|root,COG0358@2|Bacteria,1MUHC@1224|Proteobacteria,2VHI9@28216|Betaproteobacteria,3721A@32003|Nitrosomonadales	28216|Betaproteobacteria	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB_bind,DnaG_DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2
k141_2731_1	1300345.LF41_345	1.89e-15	72.4	COG0848@1|root,COG0848@2|Bacteria,1MZ6M@1224|Proteobacteria,1S8RS@1236|Gammaproteobacteria,1X7NG@135614|Xanthomonadales	135614|Xanthomonadales	U	Biopolymer transport protein	tolR	-	-	ko:K03560	-	-	-	-	ko00000,ko02000	1.A.30.2.2	-	-	ExbD
k141_2731_2	1249627.D779_1782	1.08e-53	174.0	COG0811@1|root,COG0811@2|Bacteria,1NCWW@1224|Proteobacteria,1RMD4@1236|Gammaproteobacteria,1WWA0@135613|Chromatiales	135613|Chromatiales	U	PFAM MotA TolQ ExbB proton channel	-	-	-	ko:K03562	ko01120,map01120	-	-	-	ko00000,ko02000	1.A.30.2.2	-	-	MotA_ExbB
k141_8241_1	991905.SL003B_2452	2.16e-21	95.9	COG2084@1|root,COG2084@2|Bacteria,1P0X0@1224|Proteobacteria,2U255@28211|Alphaproteobacteria,4BSC8@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	I	NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase	-	-	1.1.1.31	ko:K00020	ko00280,ko01100,map00280,map01100	-	R05066	RC00099	ko00000,ko00001,ko01000	-	-	-	NAD_binding_11,NAD_binding_2
k141_882_1	1541065.JRFE01000024_gene1098	1.17e-17	84.7	COG2197@1|root,COG2823@1|root,COG2197@2|Bacteria,COG2823@2|Bacteria,1GJ85@1117|Cyanobacteria,3VM7B@52604|Pleurocapsales	1117|Cyanobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
k141_2732_1	697282.Mettu_0289	1.1e-71	229.0	COG2843@1|root,COG2843@2|Bacteria,1P1MG@1224|Proteobacteria,1RSI9@1236|Gammaproteobacteria,1XFZ3@135618|Methylococcales	135618|Methylococcales	M	Bacterial capsule synthesis protein PGA_cap	-	-	-	-	-	-	-	-	-	-	-	-	PGA_cap
k141_7052_1	519989.ECTPHS_03879	8.94e-54	180.0	COG0189@1|root,COG0189@2|Bacteria,1MVUA@1224|Proteobacteria,1RMU0@1236|Gammaproteobacteria,1WVY1@135613|Chromatiales	135613|Chromatiales	HJ	Belongs to the prokaryotic GSH synthase family	gshB	-	6.3.2.3	ko:K01920	ko00270,ko00480,ko01100,map00270,map00480,map01100	M00118	R00497,R10994	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	GSH-S_ATP,GSH-S_N
k141_7613_1	266265.Bxe_C1060	1.49e-35	140.0	COG0145@1|root,COG0145@2|Bacteria,1MU2Y@1224|Proteobacteria,2VJUZ@28216|Betaproteobacteria,1K22A@119060|Burkholderiaceae	28216|Betaproteobacteria	EQ	5-oxoprolinase	-	-	3.5.2.14	ko:K01473	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydant_A_N,Hydantoinase_A
k141_5202_1	631362.Thi970DRAFT_04753	2.09e-71	234.0	COG0659@1|root,COG0659@2|Bacteria,1MWDF@1224|Proteobacteria,1SYC8@1236|Gammaproteobacteria,1WWSA@135613|Chromatiales	135613|Chromatiales	U	sulphate transporter	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
k141_5811_1	1265313.HRUBRA_01276	6.28e-60	199.0	COG1249@1|root,COG1249@2|Bacteria,1MU2Z@1224|Proteobacteria,1RMC0@1236|Gammaproteobacteria,1J54W@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family	gor	GO:0000166,GO:0003674,GO:0003824,GO:0004362,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015036,GO:0015037,GO:0015038,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0048037,GO:0050660,GO:0050662,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071949,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901265,GO:1901363,GO:1990748	1.8.1.7	ko:K00383	ko00480,ko04918,map00480,map04918	-	R00094,R00115	RC00011	ko00000,ko00001,ko01000	-	-	iZ_1308.Z4900	Pyr_redox_2,Pyr_redox_dim
k141_1498_1	1132855.KB913035_gene2112	2.47e-86	260.0	COG0664@1|root,COG0664@2|Bacteria,1NEQM@1224|Proteobacteria,2VH1V@28216|Betaproteobacteria,2KMFB@206350|Nitrosomonadales	206350|Nitrosomonadales	K	Transcriptional regulator, Crp Fnr family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Crp_2
k141_8860_1	990285.RGCCGE502_15545	2.9e-27	116.0	COG1228@1|root,COG1228@2|Bacteria,1MVAF@1224|Proteobacteria,2TTYC@28211|Alphaproteobacteria,4B8Y3@82115|Rhizobiaceae	28211|Alphaproteobacteria	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
k141_6437_1	159749.E7BWK7	3.36e-41	139.0	291AN@1|root,2ST4Q@2759|Eukaryota,2XG4M@2836|Bacillariophyta	2836|Bacillariophyta	S	Protein of unknown function (DUF1257)	ycf35	-	-	-	-	-	-	-	-	-	-	-	DUF1257
k141_2733_1	522306.CAP2UW1_0017	1.07e-35	137.0	COG0480@1|root,COG0480@2|Bacteria,1MVVY@1224|Proteobacteria,2VKWB@28216|Betaproteobacteria,1KR83@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	J	Elongation factor G, domain IV	-	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU
k141_265_1	391595.RLO149_c001700	4.62e-109	333.0	COG0446@1|root,COG1902@1|root,COG0446@2|Bacteria,COG1902@2|Bacteria,1MVE0@1224|Proteobacteria,2TQV0@28211|Alphaproteobacteria,2P1GE@2433|Roseobacter	28211|Alphaproteobacteria	C	COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family	fadH	-	1.3.1.34	ko:K00219	-	-	-	-	ko00000,ko01000	-	-	-	Oxidored_FMN,Pyr_redox_2
k141_3334_1	1380391.JIAS01000020_gene1642	1.81e-38	137.0	COG5285@1|root,COG5285@2|Bacteria,1MWD5@1224|Proteobacteria,2TWPJ@28211|Alphaproteobacteria,2JTE1@204441|Rhodospirillales	204441|Rhodospirillales	Q	Phytanoyl-CoA dioxygenase (PhyH)	-	-	-	-	-	-	-	-	-	-	-	-	PhyH
k141_3961_1	1317118.ATO8_08696	1.82e-68	221.0	COG4536@1|root,COG4536@2|Bacteria,1NZ99@1224|Proteobacteria,2TVZH@28211|Alphaproteobacteria,4KKQ8@93682|Roseivivax	28211|Alphaproteobacteria	P	Domain of unknown function DUF21	corB	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	CBS,CorC_HlyC,DUF21
k141_8243_1	391616.OA238_c17540	2.38e-132	380.0	COG4974@1|root,COG4974@2|Bacteria,1MVAN@1224|Proteobacteria,2UDDB@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	Phage integrase, N-terminal SAM-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
k141_2120_1	555778.Hneap_0344	1.56e-16	76.6	COG0099@1|root,COG0099@2|Bacteria,1RD1G@1224|Proteobacteria,1S3NX@1236|Gammaproteobacteria,1WYHF@135613|Chromatiales	135613|Chromatiales	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	rpsM	-	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
k141_5812_1	413404.Rmag_0035	1.6e-57	195.0	COG0843@1|root,COG0843@2|Bacteria,1MU7S@1224|Proteobacteria,1RPC3@1236|Gammaproteobacteria,1J4DV@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B	ctaD	-	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	iJN746.PP_0104	COX1
k141_7614_2	178901.AmDm5_1377	5.97e-87	263.0	COG2801@1|root,COG2801@2|Bacteria,1MVXQ@1224|Proteobacteria,2U0FG@28211|Alphaproteobacteria,2JZN8@204441|Rhodospirillales	204441|Rhodospirillales	L	HTH-like domain	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve
k141_5204_1	1174528.JH992898_gene5118	2.67e-88	288.0	COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1146@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1146@2|Bacteria,1G2E2@1117|Cyanobacteria,1JJJ8@1189|Stigonemataceae	1117|Cyanobacteria	C	Domain of unknown function	nifJ	GO:0003674,GO:0003824,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0016491,GO:0050896,GO:0055114	1.2.7.1	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00173,M00307	R01196,R10866	RC00004,RC02742	br01601,ko00000,ko00001,ko00002,ko01000	-	-	iJN678.nifJ	EKR,Fer4_16,PFOR_II,POR,POR_N,TPP_enzyme_C
k141_9514_1	998674.ATTE01000001_gene2787	3.35e-109	327.0	COG0404@1|root,COG0404@2|Bacteria,1MV96@1224|Proteobacteria,1RN2A@1236|Gammaproteobacteria,46064@72273|Thiotrichales	72273|Thiotrichales	E	The glycine cleavage system catalyzes the degradation of glycine	gcvT	-	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
k141_3962_1	420324.KI912025_gene65	1.54e-42	157.0	COG3243@1|root,COG3243@2|Bacteria,1MU68@1224|Proteobacteria,2TR7S@28211|Alphaproteobacteria,1JUA7@119045|Methylobacteriaceae	28211|Alphaproteobacteria	I	alpha beta hydrolase fold	-	-	-	ko:K03821	ko00650,map00650	-	R04254	RC00004	ko00000,ko00001,ko01000	-	-	-	PHBC_N,PhaC_N
k141_8244_1	367336.OM2255_09646	1.6e-112	330.0	COG0136@1|root,COG0136@2|Bacteria,1MUHG@1224|Proteobacteria,2TSRD@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate	asd	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
k141_266_1	946362.XP_004995507.1	5.4e-07	58.5	COG2801@1|root,KOG0017@2759|Eukaryota,38F42@33154|Opisthokonta	33154|Opisthokonta	G	retrotransposable element Tf2 155 kDa protein type 1-like	-	-	-	-	-	-	-	-	-	-	-	-	PNMA,RVT_1,gag-asp_proteas,rve,zf-CCHC,zf-H2C2
k141_4591_1	67593.Physo137253	1.58e-39	152.0	COG2801@1|root,2RRWG@2759|Eukaryota,3QH6N@4776|Peronosporales	4776|Peronosporales	L	transposition	-	-	-	-	-	-	-	-	-	-	-	-	-
k141_2734_1	35128.Thapsdraft1039	3.04e-91	269.0	2CXNY@1|root,2RYSJ@2759|Eukaryota,2XEME@2836|Bacillariophyta	2836|Bacillariophyta	C	Low-potential cytochrome c that plays a role in the oxygen-evolving complex of photosystem II	-	-	-	ko:K02720	ko00195,ko01100,map00195,map01100	-	-	-	ko00000,ko00001,ko00194	-	-	-	Cytochrom_C550
k141_2734_2	35128.Thapsdraft1037	3.74e-43	143.0	2901P@1|root,2SANI@2759|Eukaryota,2XGBV@2836|Bacillariophyta	2836|Bacillariophyta	S	Ycf66 protein N-terminus	ycf66	-	-	-	-	-	-	-	-	-	-	-	Ycf66_N
k141_3963_1	1123366.TH3_20663	5.6e-15	71.6	COG2096@1|root,COG2096@2|Bacteria,1RDUF@1224|Proteobacteria,2U5J1@28211|Alphaproteobacteria,2JRV2@204441|Rhodospirillales	204441|Rhodospirillales	S	Cobalamin adenosyltransferase	-	-	2.5.1.17	ko:K00798	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	Cob_adeno_trans
k141_883_1	159749.K0RGG6	1.4e-260	713.0	2CNIT@1|root,2QWJF@2759|Eukaryota	2759|Eukaryota	C	photosynthetic electron transport in photosystem II	psbD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009536,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464	1.10.3.9	ko:K02706	ko00195,ko01100,map00195,map01100	M00161	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	-	-	-	PSII,Photo_RC
k141_883_2	35128.Thapsdraft1545	4.4e-127	372.0	28ISP@1|root,2QR3X@2759|Eukaryota,2XE5P@2836|Bacillariophyta	2836|Bacillariophyta	P	One of the components of the core complex of photosystem II (PSII). It binds chlorophyll and helps catalyze the primary light-induced photochemical processes of PSII. PSII is a light- driven water plastoquinone oxidoreductase, using light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation	-	-	-	ko:K02705	ko00195,ko01100,map00195,map01100	M00161	-	-	ko00000,ko00001,ko00002,ko00194	-	-	-	PSII
## 3327 queries scanned
## Total time (seconds): 48.927574157714844
## Rate: 68.00 q/s